#GeneID,Symbol,GeneInfo,Localization,Process,Function,# elements 1,casTLE Effect 1,casTLE Score 1,# elements 2,casTLE Effect 2,casTLE Score 2,Combo casTLE Effect,Combo casTLE Score,Signed Combo casTLE Score,casTLE p-value,5% FDR,10% FDR,Minimum Effect Estimate,Maximum Effect Estimate
ENSMUSG00000055943,EMC7,ER membrane protein complex subunit 7,membrane|integral component of membrane|ER membrane protein complex|,biological_process|,molecular_function|carbohydrate binding|,10,2,140,10,1.8,208,1.9,347,347,1.00E-05,1,1,1.6,2.3
ENSMUSG00000033096,APMAP,adipocyte plasma membrane associated protein,cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,biosynthetic process|,arylesterase activity|strictosidine synthase activity|,10,2.2,125,10,2.3,177,2.2,302,302,1.00E-05,1,1,1.9,2.7
ENSMUSG00000047260,EMC6,ER membrane protein complex subunit 6,endoplasmic reticulum|membrane|integral component of membrane|ER membrane protein complex|,biological_process|,molecular_function|,10,3,137,10,2.8,128,2.8,264,264,1.00E-05,1,1,2.5,3.6
ENSMUSG00000098387,PET117,PET117 homolog (S. cerevisiae),mitochondrion|,None,None,10,2.6,109,10,2.3,151,2.5,259,259,1.00E-05,1,1,2.2,3.1
ENSMUSG00000030725,LIPT2,lipoyl(octanoyl) transferase 2 (putative),cytoplasm|mitochondrion|,cellular protein modification process|biological_process|lipoate biosynthetic process|,"protein binding|octanoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|ligase activity|lipoyl(octanoyl) transferase activity|",10,3.3,103,10,3.2,130,3.2,233,233,1.00E-05,1,1,2.9,4.1
ENSMUSG00000041346,WRAP53,"WD repeat containing, antisense to Trp53",nucleus|telomerase holoenzyme complex|cytoplasm|Cajal body|,telomere formation via telomerase|positive regulation of telomerase activity|,RNA binding|,10,2,69.9,10,1.5,152,1.7,219,219,1.00E-05,1,1,1.4,2.3
ENSMUSG00000024965,FERMT3,fermitin family homolog 3 (Drosophila),podosome|membrane|cell junction|cell projection|extracellular vesicular exosome|,cell adhesion|leukocyte cell-cell adhesion|leukocyte cell-cell adhesion|integrin-mediated signaling pathway|integrin activation|integrin activation|regulation of cell-cell adhesion mediated by integrin|regulation of cell-cell adhesion mediated by integrin|substrate adhesion-dependent cell spreading|platelet aggregation|,integrin binding|integrin binding|protein binding|,10,1.3,92.7,10,1.3,125,1.3,217,217,1.00E-05,1,1,1.1,1.7
ENSMUSG00000021786,OXSM,"3-oxoacyl-ACP synthase, mitochondrial",mitochondrion|mitochondrion|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|acyl-CoA metabolic process|metabolic process|short-chain fatty acid biosynthetic process|medium-chain fatty acid biosynthetic process|,"catalytic activity|3-oxoacyl-[acyl-carrier-protein] synthase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|",10,1.9,89.9,10,1.5,121,1.6,209,209,1.00E-05,1,1,1.4,2.2
ENSMUSG00000033809,ALG3,"asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,mannosylation|,"alpha-1,3-mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity|",10,1.1,83.3,10,1.4,107,1.2,188,188,1.00E-05,1,1,1,1.6
ENSMUSG00000030842,LAMTOR1,"late endosomal/lysosomal adaptor, MAPK and MTOR activator 1",lysosome|endosome|Golgi apparatus|plasma membrane|membrane|late endosome membrane|intracellular membrane-bounded organelle|membrane raft|extracellular vesicular exosome|Ragulator complex|,regulation of receptor recycling|endosome organization|lysosome organization|regulation of cholesterol esterification|regulation of cholesterol efflux|cell growth|positive regulation of TOR signaling|lysosome localization|endosome localization|cellular protein localization|cellular protein localization|cholesterol homeostasis|positive regulation of MAPK cascade|positive regulation of GTPase activity|regulation of cholesterol import|cellular response to amino acid stimulus|,guanyl-nucleotide exchange factor activity|protein binding|protein complex scaffold|,10,1.2,79.9,10,1,73.5,1.1,152,152,1.00E-05,1,1,0.9,1.4
ENSMUSG00000038888,CTU1,cytosolic thiouridylase subunit 1 homolog (S. pombe),cytoplasm|mitochondrion|,tRNA wobble uridine modification|tRNA processing|biological_process|tRNA thio-modification|,"tRNA binding|molecular_function|telomerase activity|RNA binding|RNA helicase activity|DNA primase activity|sulfate adenylyltransferase activity|RNA guanylyltransferase activity|tRNA guanylyltransferase activity|mannose-phosphate guanylyltransferase activity|transferase activity|DNA/RNA helicase activity|CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity|phospholactate guanylyltransferase activity|ATP:coenzyme F420 adenylyltransferase activity|UDP-N-acetylgalactosamine diphosphorylase activity|",10,2,44.7,10,1.3,107,1.4,149,149,1.00E-05,1,1,1.2,2.2
ENSMUSG00000060216,ARRB2,"arrestin, beta 2",intracellular|nucleus|cytoplasm|plasma membrane|coated pit|postsynaptic density|membrane|basolateral plasma membrane|endocytic vesicle|cytoplasmic vesicle|dendritic spine|postsynaptic membrane|,"regulation of protein phosphorylation|regulation of protein phosphorylation|positive regulation of protein phosphorylation|G-protein coupled receptor internalization|desensitization of G-protein coupled receptor protein signaling pathway by arrestin|positive regulation of receptor internalization|transcription from RNA polymerase II promoter|transport|endocytosis|signal transduction|transforming growth factor beta receptor signaling pathway|G-protein coupled receptor signaling pathway|adult walking behavior|regulation of G-protein coupled receptor protein signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|negative regulation of signal transduction|protein transport|protein ubiquitination|negative regulation of protein ubiquitination|positive regulation of protein ubiquitination|receptor internalization|negative regulation of NF-kappaB transcription factor activity|positive regulation of synaptic transmission, dopaminergic|negative regulation of interleukin-1 beta production|negative regulation of interleukin-12 production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|positive regulation of peptidyl-serine phosphorylation|negative regulation of toll-like receptor signaling pathway|negative regulation of GTPase activity|negative regulation of smooth muscle cell apoptotic process|follicle-stimulating hormone signaling pathway|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of natural killer cell mediated cytotoxicity|positive regulation of peptidyl-tyrosine phosphorylation|detection of temperature stimulus involved in sensory perception of pain|positive regulation of protein kinase B signaling|positive regulation of protein kinase B signaling|positive regulation of calcium ion transport|cell chemotaxis|regulation of androgen receptor signaling pathway|positive regulation of ERK1 and ERK2 cascade|negative regulation of release of cytochrome c from mitochondria|positive regulation of DNA biosynthetic process|",G-protein coupled receptor binding|receptor binding|protein binding|enzyme binding|protein domain specific binding|ubiquitin protein ligase binding|alpha-1A adrenergic receptor binding|alpha-1B adrenergic receptor binding|angiotensin receptor binding|type 1 angiotensin receptor binding|D1 dopamine receptor binding|follicle-stimulating hormone receptor binding|type 2A serotonin receptor binding|protein complex binding|protein complex scaffold|protein kinase B binding|mitogen-activated protein kinase binding|14-3-3 protein binding|,10,1.2,98.1,10,0.9,52.5,1.1,148,148,1.00E-05,1,1,0.9,1.4
ENSMUSG00000019864,RTN4IP1,reticulon 4 interacting protein 1,mitochondrion|mitochondrion|,oxidation-reduction process|,zinc ion binding|oxidoreductase activity|,10,2,37.5,10,1.7,96.1,1.7,133,133,1.00E-05,1,1,1.5,2.4
ENSMUSG00000091780,SCO2,SCO cytochrome oxidase deficient homolog 2 (yeast),nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|myofibril|,eye development|in utero embryonic development|muscle system process|copper ion transport|cellular copper ion homeostasis|respiratory chain complex IV assembly|response to activity|respiratory electron transport chain|copper ion homeostasis|,copper ion binding|metal ion binding|,9,3,61.5,8,1.4,73.2,1.4,131,131,1.00E-05,1,1,1.2,3.3
ENSMUSG00000020718,POLG2,"polymerase (DNA directed), gamma 2, accessory subunit",mitochondrion|mitochondrial nucleoid|extracellular vesicular exosome|,DNA replication|DNA-dependent DNA replication|DNA repair|DNA biosynthetic process|,DNA binding|DNA-directed DNA polymerase activity|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|identical protein binding|,10,2.4,50,10,2,68.7,2.1,117,117,1.00E-05,1,1,1.7,2.8
ENSMUSG00000035142,NUBPL,nucleotide binding protein-like,mitochondrion|mitochondrion|,mitochondrial respiratory chain complex I assembly|mitochondrion morphogenesis|,"nucleotide binding|ATP binding|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,2,47.7,10,1.9,65.7,1.9,113,113,1.00E-05,1,1,1.6,2.7
ENSMUSG00000020132,RAB21,"RAB21, member RAS oncogene family",endosome|endoplasmic reticulum|Golgi apparatus|membrane|cytoplasmic vesicle|extracellular vesicular exosome|,GTP catabolic process|transport|small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|,10,-1.1,72.7,10,-0.9,41.3,-1,113,-113,1.00E-05,1,1,-1.3,-0.8
ENSMUSG00000003778,BRD8,bromodomain containing 8,Swr1 complex|nucleus|mitochondrion|NuA4 histone acetyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|regulation of growth|histone H4 acetylation|histone H2A acetylation|",molecular_function|,10,1.8,43.4,10,1.9,67.7,1.8,111,111,1.00E-05,1,1,1.4,2.4
ENSMUSG00000029670,ING3,"inhibitor of growth family, member 3",Swr1 complex|nucleus|nucleolus|cytoplasm|Piccolo NuA4 histone acetyltransferase complex|NuA4 histone acetyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|regulation of growth|positive regulation of apoptotic process|histone H4 acetylation|histone H2A acetylation|",histone acetyltransferase activity|zinc ion binding|methylated histone binding|metal ion binding|,10,1.5,25.3,10,1.2,86,1.3,109,109,4.00E-05,1,1,1.1,1.8
ENSMUSG00000022299,SLC25A32,"solute carrier family 25, member 32",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,2.4,45.1,10,2,63.1,2.1,107,107,5.00E-05,1,1,1.7,2.8
ENSMUSG00000027195,HSD17B12,hydroxysteroid (17-beta) dehydrogenase 12,endoplasmic reticulum|membrane|integral component of membrane|extracellular matrix|,lipid metabolic process|steroid biosynthetic process|metabolic process|positive regulation of cell-substrate adhesion|extracellular matrix organization|oxidation-reduction process|,"fibronectin binding|estradiol 17-beta-dehydrogenase activity|collagen binding|heparin binding|oxidoreductase activity|enoyl-[acyl-carrier-protein] reductase activity|2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity|cis-2,3-dihydrodiol DDT dehydrogenase activity|trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity|cis-chlorobenzene dihydrodiol dehydrogenase activity|2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity|trans-1,2-dihydrodiolphenanthrene dehydrogenase activity|3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity|benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity|benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity|citronellyl-CoA dehydrogenase activity|menthone dehydrogenase activity|phthalate 3,4-cis-dihydrodiol dehydrogenase activity|cinnamate reductase activity|NADPH-dependent curcumin reductase activity|NADPH-dependent dihydrocurcumin reductase activity|",10,1.3,49.9,10,1.4,58,1.4,107,107,5.00E-05,1,1,1,1.8
ENSMUSG00000026810,DPM2,dolichol-phosphate (beta-D) mannosyltransferase 2,glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|dolichol-phosphate-mannose synthase complex|perinuclear region of cytoplasm|,GPI anchor biosynthetic process|macromolecule biosynthetic process|dolichol metabolic process|regulation of protein stability|regulation of catalytic activity|mannosylation|,"dolichyl-phosphate beta-D-mannosyltransferase activity|dolichyl-phosphate beta-D-mannosyltransferase activity|protein binding|transferase activity|transferase activity, transferring glycosyl groups|enzyme regulator activity|",10,0.7,17.2,10,1.4,86.9,1.3,99.4,99.4,6.00E-05,1,1,0.9,1.7
ENSMUSG00000018442,DERL2,"Der1-like domain family, member 2",intracellular|cell|early endosome|late endosome|endoplasmic reticulum|endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,"suckling behavior|response to unfolded protein|positive regulation of cell proliferation|positive regulation of cell growth|ER-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum unfolded protein response|retrograde protein transport, ER to cytosol|retrograde protein transport, ER to cytosol|",molecular_function|,9,0.9,25.3,10,1.1,73.1,1,97.3,97.3,6.00E-05,1,1,0.8,1.4
ENSMUSG00000028013,PPA2,pyrophosphatase (inorganic) 2,cytoplasm|mitochondrion|extracellular vesicular exosome|,phosphate-containing compound metabolic process|dephosphorylation|,magnesium ion binding|inorganic diphosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,2.5,47.4,10,1.1,46.3,1,91.7,91.7,8.00E-05,1,1,0.7,2.4
ENSMUSG00000026500,COX20,COX20 Cox2 chaperone,mitochondrion|mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,9,1,44.6,9,1.1,46.1,1.1,90.1,90.1,8.00E-05,1,1,0.8,1.4
ENSMUSG00000002846,TIMMDC1,translocase of inner mitochondrial membrane domain containing 1,nucleus|mitochondrion|mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1,23.2,10,1.6,69.4,1.5,89.3,89.3,8.00E-05,1,1,1.1,2.2
ENSMUSG00000034807,COLGALT1,N/A,None,None,None,10,1,35.2,10,1.5,52.2,1,85.6,85.6,0.0001,1,1,0.7,1.6
ENSMUSG00000067274,RPLP0,"ribosomal protein, large, P0",intracellular|nucleus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|extracellular vesicular exosome|,translational elongation|ribosome biogenesis|cellular response to interleukin-4|,structural constituent of ribosome|poly(A) RNA binding|,5,2.2,24.6,7,1.8,54.3,2.1,77.6,77.6,0.00016,1,1,1.7,3.7
ENSMUSG00000022386,TRMU,tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase,cytoplasm|mitochondrion|,tRNA processing|biological_process|,tRNA binding|nucleotide binding|molecular_function|RNA binding|ATP binding|transferase activity|sulfurtransferase activity|,8,1,13.2,8,1.7,66.9,1.7,77.3,77.3,0.00019,1,1,1.4,2.6
ENSMUSG00000019809,PEX3,peroxisomal biogenesis factor 3,nucleus|peroxisome|peroxisomal membrane|integral component of peroxisomal membrane|endoplasmic reticulum|cytosol|integral component of plasma membrane|membrane|membrane|integral component of membrane|protein-lipid complex|intracellular membrane-bounded organelle|protein complex|,peroxisome organization|peroxisome membrane biogenesis|protein import into peroxisome membrane|,lipid binding|protein dimerization activity|,10,0.8,17.7,10,1.3,60.2,1.1,74.6,74.6,0.00023,1,1,0.8,1.6
ENSMUSG00000022021,DIAP3,diaphanous homolog 3 (Drosophila),nucleus|cytoplasm|,cellular component organization|actin cytoskeleton organization|,actin binding|Rho GTPase binding|,10,0.9,18.4,10,1,54.9,1,72.9,72.9,0.0003,1,1,0.8,1.4
ENSMUSG00000045973,SLC25A51,"solute carrier family 25, member 51",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,1.2,14.4,10,1.7,59.3,1.6,72.2,72.2,0.00035,1,1,1.3,2.4
ENSMUSG00000031729,IST1,increased sodium tolerance 1 homolog (yeast),endoplasmic reticulum-Golgi intermediate compartment|centrosome|cytosol|midbody|cytoplasmic vesicle|extracellular vesicular exosome|Flemming body|,cytokinesis|cell cycle|protein localization|abscission|viral release from host cell|establishment of protein localization|positive regulation of proteolysis|viral capsid secondary envelopment|positive regulation of collateral sprouting|cell division|,protein binding|protein domain specific binding|protein complex binding|MIT domain binding|,8,-0.9,18.5,9,-1.3,55.4,-1.3,71.7,-71.7,0.00038,1,1,-1.7,-0.9
ENSMUSG00000094130,RPP14,ribonuclease P 14 subunit,cellular_component|nucleus|,tRNA processing|biological_process|,ribonuclease P activity|ribonuclease activity|hydrolase activity|,10,1.9,32.7,10,1,40.2,1.2,69.6,69.6,0.00049,1,1,0.9,2.2
ENSMUSG00000024208,UQCC2,ubiquinol-cytochrome c reductase complex assembly factor 2,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|mitochondrial matrix|membrane|mitochondrial nucleoid|,regulation of oxidative phosphorylation|regulation of oxidative phosphorylation|regulation of insulin secretion|regulation of skeletal muscle cell differentiation|,molecular_function|,10,1.1,33.7,10,1.5,37.4,1.3,69.3,69.3,0.0005,1,1,0.8,1.9
ENSMUSG00000021241,ISCA2,iron-sulfur cluster assembly 2 homolog (S. cerevisiae),mitochondrion|,biological_process|iron-sulfur cluster assembly|,molecular_function|structural molecule activity|metal ion binding|iron-sulfur cluster binding|,9,0.8,25.6,9,1,42,1,67.1,67.1,0.00061,1,1,0.8,1.4
ENSMUSG00000020078,VPS26A,vacuolar protein sorting 26 homolog A (yeast),cytoplasm|endosome|endosome|cytosol|membrane|vesicle|intracellular membrane-bounded organelle|extracellular vesicular exosome|,"transport|protein transport|retrograde transport, endosome to Golgi|",protein binding|,10,0.8,27.1,10,0.7,37.9,0.7,64,64,0.00072,1,1,0.6,1
ENSMUSG00000029625,CPSF4,cleavage and polyadenylation specific factor 4,nucleus|mRNA cleavage and polyadenylation specificity factor complex|,mRNA processing|biological_process|,nucleic acid binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,9,1.5,25.4,9,0.8,42.4,1.1,63.8,63.8,0.00073,1,1,0.7,1.6
ENSMUSG00000078572,1810043H04RIK,RIKEN cDNA 1810043H04 gene,mitochondrion|,biological_process|,molecular_function|,10,2.2,26.5,10,1.5,39.5,1.8,62.6,62.6,0.00086,1,1,1.3,3.1
ENSMUSG00000015002,EFR3A,EFR3 homolog A (S. cerevisiae),cornified envelope|intracellular|plasma membrane|membrane|extracellular vesicular exosome|,single organismal cell-cell adhesion|,protein homodimerization activity|,10,1.3,15.6,10,1.1,46.1,1.1,61.2,61.2,0.00102,1,1,0.7,1.6
ENSMUSG00000028646,RRAGC,Ras-related GTP binding C,nucleus|cytoplasm|lysosome|intracellular membrane-bounded organelle|,GTP catabolic process|GTP catabolic process|,nucleotide binding|GTPase activity|GTPase activity|GTP binding|GDP binding|protein heterodimerization activity|,8,1.1,36.9,8,0.8,25,0.9,60.8,60.8,0.00113,1,1,0.7,1.4
ENSMUSG00000020573,PIK3CG,"phosphoinositide-3-kinase, catalytic, gamma polypeptide","cytoplasm|plasma membrane|phosphatidylinositol 3-kinase complex|phosphatidylinositol 3-kinase complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex|membrane|",angiogenesis|immune system process|positive regulation of acute inflammatory response|protein phosphorylation|endocytosis|chemotaxis|inflammatory response|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|negative regulation of triglyceride catabolic process|phosphatidylinositol 3-kinase signaling|phosphorylation|secretory granule localization|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol-3-phosphate biosynthetic process|positive regulation of MAP kinase activity|phosphatidylinositol phosphorylation|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|positive regulation of protein kinase B signaling|hepatocyte apoptotic process|negative regulation of fibroblast apoptotic process|,"nucleotide binding|protein serine/threonine kinase activity|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|1-phosphatidylinositol-4-phosphate 3-kinase activity|ephrin receptor binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|",10,-1,49.8,10,-0.7,11.7,-0.8,59.8,-59.8,0.00124,1,1,-1.3,-0.6
ENSMUSG00000032349,ELOVL5,"ELOVL family member 5, elongation of long chain fatty acids (yeast)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,"lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation, monounsaturated fatty acid|fatty acid elongation, polyunsaturated fatty acid|very long-chain fatty acid biosynthetic process|",fatty acid elongase activity|transferase activity|,10,0.7,18.2,10,1,42.9,0.9,59.6,59.6,0.00124,1,1,0.7,1.2
ENSMUSG00000049960,MRPS16,mitochondrial ribosomal protein S16,intracellular|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|biological_process|,molecular_function|structural constituent of ribosome|,10,0.8,19,10,0.9,40.7,0.8,59.2,59.2,0.0013,1,1,0.7,1.2
ENSMUSG00000038900,RPL12,ribosomal protein L12,nucleus|nucleolus|cytoplasm|membrane|cytosolic large ribosomal subunit|extracellular vesicular exosome|,None,protein binding|poly(A) RNA binding|,9,1,12.2,9,1,46.9,1,58.7,58.7,0.00133,1,1,0.8,1.5
ENSMUSG00000005907,PEX1,peroxisomal biogenesis factor 1,cytoplasm|peroxisome|peroxisome|peroxisomal membrane|cytosol|membrane|intracellular membrane-bounded organelle|,ATP catabolic process|protein targeting to peroxisome|transport|peroxisome organization|protein transport|protein import into peroxisome matrix|microtubule-based peroxisome localization|,"nucleotide binding|ATP binding|protein C-terminus binding|lipid binding|protein complex binding|ATPase activity, coupled|",9,1.4,24.1,10,1.1,34.7,1.2,58,58,0.00144,1,1,0.9,1.8
ENSMUSG00000032178,ILF3,interleukin enhancer binding factor 3,nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|membrane|ribonucleoprotein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|protein methylation|negative regulation of translation|negative regulation of viral genome replication|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|defense response to virus|",DNA binding|DNA binding|RNA binding|double-stranded RNA binding|enzyme binding|poly(A) RNA binding|,10,-0.5,11.5,10,-0.9,49.8,-0.9,56.9,-56.9,0.00162,1,1,-1.2,-0.7
ENSMUSG00000056851,PCBP2,poly(rC) binding protein 2,nucleus|cytoplasm|membrane|ribonucleoprotein complex|extracellular vesicular exosome|,immune system process|proteasome-mediated ubiquitin-dependent protein catabolic process|innate immune response|negative regulation of defense response to virus|defense response to virus|,DNA binding|RNA binding|enzyme binding|ubiquitin protein ligase binding|poly(A) RNA binding|,10,0.6,18.4,10,0.6,34.8,0.6,52.8,52.8,0.00281,0,1,0.5,0.9
ENSMUSG00000026457,ADIPOR1,adiponectin receptor 1,plasma membrane|plasma membrane|plasma membrane|membrane|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|hormone-mediated signaling pathway|hormone-mediated signaling pathway|fatty acid oxidation|fatty acid oxidation|negative regulation of cell growth|leptin-mediated signaling pathway|adiponectin-activated signaling pathway|adiponectin-activated signaling pathway|adiponectin-activated signaling pathway|positive regulation of JAK-STAT cascade|positive regulation of insulin receptor signaling pathway|,receptor activity|protein binding|protein kinase binding|hormone binding|hormone binding|hormone binding|identical protein binding|protein heterodimerization activity|adiponectin binding|,10,0.7,20.5,10,0.5,32.9,0.6,52.7,52.7,0.00284,0,1,0.4,0.9
ENSMUSG00000015711,PRUNE,prune homolog (Drosophila),nucleus|cytoplasm|cell junction|,biological_process|,molecular_function|inorganic diphosphatase activity|pyrophosphatase activity|hydrolase activity|metal ion binding|,10,0.8,13.8,10,0.9,39.1,0.9,52.5,52.5,0.00293,0,1,0.6,1.3
ENSMUSG00000020630,RNASEH1,ribonuclease H1,nucleus|cytoplasm|mitochondrion|mitochondrion|,"mitochondrial DNA replication|RNA phosphodiester bond hydrolysis, endonucleolytic|",magnesium ion binding|nucleic acid binding|nuclease activity|endonuclease activity|RNA-DNA hybrid ribonuclease activity|RNA-DNA hybrid ribonuclease activity|hydrolase activity|protein homodimerization activity|metal ion binding|,10,2.3,25.3,10,2.4,27,2.4,51.7,51.7,0.00318,0,1,2,3.7
ENSMUSG00000027998,PLRG1,"pleiotropic regulator 1, PRL1 homolog (Arabidopsis)",nucleus|spliceosomal complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|protein localization to nucleus|positive regulation of G1/S transition of mitotic cell cycle|,molecular_function|,9,0.6,7.07,9,1.7,49.1,1.7,51.6,51.6,0.00321,0,1,0.9,2.6
ENSMUSG00000032059,ALG9,"asparagine-linked glycosylation 9 (alpha 1,2 mannosyltransferase)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,None,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity|dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity|",10,0.8,25.4,10,0.7,26.1,0.7,51,51,0.00349,0,1,0.5,1.1
ENSMUSG00000049482,CTU2,cytosolic thiouridylase subunit 2 homolog (S. pombe),cytoplasm|protein complex|,tRNA wobble uridine modification|tRNA processing|biological_process|tRNA thio-modification|,tRNA binding|molecular_function|,10,1.2,28.5,10,0.6,26.3,0.9,50.9,50.9,0.00353,0,1,0.6,1.4
ENSMUSG00000092074,DYNLT1A,dynein light chain Tctex-type 1A,cellular_component|,biological_process|,identical protein binding|,10,1.1,42.4,10,0.6,11.8,0.9,50.8,50.8,0.00359,0,1,0.6,1.4
ENSMUSG00000095677,DYNLT1F,dynein light chain Tctex-type 1F,cellular_component|,biological_process|,identical protein binding|,10,1.1,42.4,10,0.6,11.8,0.9,50.8,50.8,0.00359,0,1,0.6,1.4
ENSMUSG00000018677,SLC25A39,"solute carrier family 25, member 39",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,heme biosynthetic process|transport|,None,10,1.1,21.7,10,0.5,29.7,0.9,50.5,50.5,0.00375,0,1,0.5,1.4
ENSMUSG00000039640,MRPL12,mitochondrial ribosomal protein L12,intracellular|mitochondrion|mitochondrion|mitochondrial ribosome|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,"transcription from mitochondrial promoter|translation|positive regulation of transcription, DNA-templated|",structural constituent of ribosome|,10,0.8,3.74,9,1.6,48,1.6,49.2,49.2,0.00456,0,1,1,2.7
ENSMUSG00000025508,RPLP2,"ribosomal protein, large P2",intracellular|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translational elongation|,molecular_function|structural constituent of ribosome|,5,1.7,11,5,1.4,38.8,1.5,48.7,48.7,0.00493,0,1,1.1,2.6
ENSMUSG00000005882,UQCC1,ubiquinol-cytochrome c reductase complex assembly factor 1,mitochondrion|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|,biological_process|,molecular_function|,10,0.6,7.74,10,1.4,41.5,1.3,47,47,0.00646,0,0,0.6,1.9
ENSMUSG00000018661,COG1,component of oligomeric golgi complex 1,Golgi apparatus|membrane|Golgi transport complex|,transport|protein transport|,None,8,0.8,13.6,9,1,33.4,0.9,45.9,45.9,0.0073,0,0,0.6,1.4
ENSMUSG00000024829,MRPL21,mitochondrial ribosomal protein L21,intracellular|mitochondrion|ribosome|ribonucleoprotein complex|,translation|biological_process|,RNA binding|structural constituent of ribosome|poly(A) RNA binding|,9,0.9,19.9,9,1.6,28.6,1.5,45.5,45.5,0.00758,0,0,0.7,2.2
ENSMUSG00000030619,EED,embryonic ectoderm development,sex chromatin|nucleus|nucleus|chromosome|cytoplasm|ESC/E(Z) complex|ESC/E(Z) complex|pronucleus|,"regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone methylation|histone methylation|positive regulation of histone H3-K27 methylation|",chromatin binding|protein binding|histone methyltransferase activity|identical protein binding|,10,0.8,20.2,10,0.8,25.3,0.8,45.1,45.1,0.00795,0,0,0.6,1.1
ENSMUSG00000021607,MRPL36,mitochondrial ribosomal protein L36,intracellular|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,10,1.3,25.7,10,1.1,17.8,1.1,42.9,42.9,0.00984,0,0,0.8,1.9
ENSMUSG00000030432,RPL28,ribosomal protein L28,intracellular|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|dendrite|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|cell body|extracellular vesicular exosome|,translation|,structural constituent of ribosome|poly(A) RNA binding|,8,1.1,26.3,9,-1.5,28.2,-1.4,42.7,-42.7,0.0101,0,0,-2.6,-1
ENSMUSG00000079677,FDX1L,ferredoxin 1-like,mitochondrion|,transport|biological_process|oxidation-reduction process|,"electron carrier activity|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",9,0.6,11.3,8,1.3,35.9,1.1,42.7,42.7,0.0101,0,0,0.7,1.7
ENSMUSG00000024902,MRPL11,mitochondrial ribosomal protein L11,mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,8,1,8.73,9,1.9,36.3,1.9,42.5,42.5,0.0103,0,0,1,3.1
ENSMUSG00000046330,RPL37A,ribosomal protein L37a,intracellular|nucleus|ribosome|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,structural constituent of ribosome|poly(A) RNA binding|metal ion binding|,5,-1.2,41.7,4,-0.4,3.01,-1.1,41.9,-41.9,0.0108,0,0,-1.9,-0.8
ENSMUSG00000025825,ISCU,IscU iron-sulfur cluster scaffold homolog (E. coli),cytoplasm|mitochondrion|mitochondrion|cytosol|,iron-sulfur cluster assembly|,iron ion binding|protein complex scaffold|metal ion binding|iron-sulfur cluster binding|,9,0.1,0.211,9,1.5,43.6,1.5,41.1,41.1,0.0116,0,0,0.9,2.7
ENSMUSG00000046573,LYRM4,LYR motif containing 4,nucleus|mitochondrion|,biological_process|,molecular_function|,7,1.2,22.7,7,0.9,17.1,1,39,39,0.0143,0,0,0.7,1.7
ENSMUSG00000055334,SNUPN,snurportin 1,nucleus|cytoplasm|extracellular vesicular exosome|,protein import into nucleus|transport|snRNA import into nucleus|,molecular_function|RNA binding|protein transporter activity|,10,1,28,10,0.5,13.3,0.7,38.5,38.5,0.0149,0,0,0.4,1.2
ENSMUSG00000023723,MRPS23,mitochondrial ribosomal protein S23,mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|nuclear membrane|intermediate filament cytoskeleton|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,0.8,23.6,9,1,14.8,1,37.8,37.8,0.0157,0,0,0.5,1.5
ENSMUSG00000032939,NUP93,nucleoporin 93,nucleus|nuclear pore|membrane|membrane|nuclear membrane|nuclear periphery|,transport|protein transport|mRNA transport|nuclear pore complex assembly|,structural constituent of nuclear pore|,9,-0.7,7.49,8,1.1,33.2,1,37.1,37.1,0.0167,0,0,0.7,1.7
ENSMUSG00000027222,PEX16,peroxisomal biogenesis factor 16,peroxisome|peroxisomal membrane|peroxisomal membrane|integral component of peroxisomal membrane|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,protein targeting to peroxisome|peroxisome organization|peroxisome membrane biogenesis|protein import into peroxisome matrix|protein to membrane docking|ER-dependent peroxisome organization|protein import into peroxisome membrane|protein localization to endoplasmic reticulum|,protein C-terminus binding|,10,0.7,12.4,10,0.8,24.9,0.8,36.6,36.6,0.0173,0,0,0.6,1.1
ENSMUSG00000003226,RANBP2,RAN binding protein 2,nucleus|nuclear pore|mitochondrion|membrane|,protein peptidyl-prolyl isomerization|protein folding|transport|protein transport|negative regulation of glucokinase activity|intracellular transport|mRNA transport|regulation of gluconeogenesis involved in cellular glucose homeostasis|,"RNA binding|peptidyl-prolyl cis-trans isomerase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,1.4,11.7,10,0.9,24.5,1,34.7,34.7,0.0205,0,0,0.7,1.7
ENSMUSG00000039018,MTG1,mitochondrial GTPase 1 homolog (S. cerevisiae),mitochondrion|mitochondrial inner membrane|mitochondrial matrix|mitochondrial ribosome|membrane|,GTP catabolic process|GTP catabolic process|regulation of translation|ribosome biogenesis|regulation of respiratory system process|regulation of mitochondrial translation|,nucleotide binding|GTPase activity|GTPase activity|GTP binding|,10,0.5,7.92,10,1.7,33,1.6,34.3,34.3,0.0212,0,0,0.7,2.3
ENSMUSG00000062232,RAPGEF2,Rap guanine nucleotide exchange factor (GEF) 2,intracellular|cytoplasm|endosome|late endosome|plasma membrane|membrane|cell junction|neuron projection|neuronal cell body|protein complex|synapse|perinuclear region of cytoplasm|,blood vessel development|neuron migration|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|neuropeptide signaling pathway|small GTPase mediated signal transduction|multicellular organismal development|nervous system development|negative regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of neuron projection development|cAMP-mediated signaling|cAMP-mediated signaling|ventricular system development|forebrain neuron development|cell differentiation|neuron projection development|neuron projection development|brain-derived neurotrophic factor receptor signaling pathway|positive regulation of protein binding|positive regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|Rap protein signal transduction|positive regulation of Rap GTPase activity|positive regulation of Rap GTPase activity|positive regulation of Rap GTPase activity|nerve growth factor signaling pathway|positive regulation of cAMP-mediated signaling|positive regulation of protein kinase activity|positive regulation of protein kinase activity|negative regulation of melanin biosynthetic process|regulation of synaptic plasticity|negative regulation of dendrite morphogenesis|negative regulation of dendrite morphogenesis|regulation of small GTPase mediated signal transduction|establishment of endothelial barrier|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cellular response to cAMP|cellular response to cAMP|cellular response to cAMP|cellular response to cGMP|adenylate cyclase-activating adrenergic receptor signaling pathway|regulation of cell junction assembly|cellular response to nerve growth factor stimulus|positive regulation of cAMP-dependent protein kinase activity|positive regulation of cAMP-dependent protein kinase activity|positive regulation of dendritic cell apoptotic process|positive regulation of dendritic cell apoptotic process|positive regulation of vasculogenesis|positive regulation of neuron migration|,guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|GTPase activator activity|Rap guanyl-nucleotide exchange factor activity|Rap guanyl-nucleotide exchange factor activity|Rap guanyl-nucleotide exchange factor activity|protein kinase binding|PDZ domain binding|beta-1 adrenergic receptor binding|Rap GTPase activator activity|WW domain binding|,9,-0.3,3.38,9,-0.8,33.2,-0.6,33.7,-33.7,0.0227,0,0,-1.2,-0.4
ENSMUSG00000038880,MRPS34,mitochondrial ribosomal protein S34,mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,10,0.6,9.33,9,0.8,24.7,0.7,33.3,33.3,0.0234,0,0,0.5,1.2
ENSMUSG00000003299,MRPL4,mitochondrial ribosomal protein L4,mitochondrion|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,8,-0.9,6.41,9,1.3,29.4,1.2,33.2,33.2,0.0236,0,0,0.7,1.9
ENSMUSG00000030763,LCMT1,leucine carboxyl methyltransferase 1,cytosol|,protein methylation|protein methylation|protein methylation|C-terminal protein methylation|regulation of glucose metabolic process|negative regulation of protein complex assembly|methylation|regulation of apoptotic process|regulation of mitotic cell cycle spindle assembly checkpoint|,protein C-terminal carboxyl O-methyltransferase activity|methyltransferase activity|protein methyltransferase activity|transferase activity|,10,1.5,16.5,10,0.9,18.8,0.9,32.8,32.8,0.0243,0,0,0.7,1.8
ENSMUSG00000028136,SNX27,sorting nexin family member 27,immunological synapse|intracellular|cell|nucleus|cytoplasm|endosome|early endosome|membrane|retromer complex|WASH complex|,"transport|intracellular protein transport|signal transduction|endosome to lysosome transport|protein transport|endosomal transport|endosomal transport|retrograde transport, endosome to plasma membrane|",protein binding|lipid binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol binding|,10,1,15.6,10,0.6,17.7,0.7,32.2,32.2,0.0258,0,0,0.4,1.2
ENSMUSG00000058793,CDS2,CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2,mitochondrion|mitochondrial inner membrane|endoplasmic reticulum|endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|phototransduction|phospholipid biosynthetic process|glycosylation|,"phosphatidate cytidylyltransferase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|nucleotidyltransferase activity|",10,0.3,0.137,10,1.2,33.7,1.2,32.1,32.1,0.026,0,0,0.7,1.9
ENSMUSG00000064326,SIVA1,"SIVA1, apoptosis-inducing factor",nucleus|nucleoplasm|cytoplasm|mitochondrion|,apoptotic process|activation-induced cell death of T cells|response to virus|negative regulation of NF-kappaB transcription factor activity|extrinsic apoptotic signaling pathway|positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|,virus receptor activity|tumor necrosis factor receptor binding|CD27 receptor binding|CD27 receptor binding|zinc ion binding|metal ion binding|,10,0.8,16.5,10,0.6,14.8,0.7,30.3,30.3,0.0312,0,0,0.5,1.1
ENSMUSG00000038209,ITLN1,intelectin 1 (galactofuranose binding),extracellular region|plasma membrane|membrane|anchored component of membrane|brush border membrane|receptor complex|membrane raft|extracellular vesicular exosome|,positive regulation of protein phosphorylation|response to nematode|positive regulation of glucose import|,carbohydrate binding|,9,0.8,8.59,9,1,21.2,0.9,29.2,29.2,0.035,0,0,0.5,1.4
ENSMUSG00000062381,VPS28,vacuolar protein sorting 28 (yeast),ESCRT I complex|cytoplasm|endosome|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,transport|protein transport|negative regulation of protein ubiquitination|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|,protein binding|,7,1,13.2,7,0.8,16.2,0.8,28.8,28.8,0.0364,0,0,0.6,1.5
ENSMUSG00000067825,PEX26,peroxisomal biogenesis factor 26,peroxisome|integral component of peroxisomal membrane|membrane|integral component of membrane|,transport|protein transport|protein import into peroxisome matrix|protein import into peroxisome membrane|,protein C-terminus binding|protein complex binding|ATPase binding|,10,1,16.6,10,0.7,12.5,0.7,28.5,28.5,0.0377,0,0,0.4,1.3
ENSMUSG00000020459,MTIF2,mitochondrial translational initiation factor 2,intracellular|mitochondrion|mitochondrion|mitochondrion|,translation|translational initiation|biological_process|,nucleotide binding|translation initiation factor activity|GTPase activity|GTP binding|poly(A) RNA binding|,10,0.8,20.3,10,0.6,8.04,0.7,27.3,27.3,0.0433,0,0,0.5,1.3
ENSMUSG00000018848,RARS,arginyl-tRNA synthetase,nucleus|cytoplasm|mitochondrion|membrane|aminoacyl-tRNA synthetase multienzyme complex|extracellular vesicular exosome|,translation|tRNA aminoacylation for protein translation|arginyl-tRNA aminoacylation|,tRNA binding|nucleotide binding|aminoacyl-tRNA ligase activity|arginine-tRNA ligase activity|ATP binding|ligase activity|arginine binding|,10,-0.8,7.77,9,1,25.9,0.9,26.9,26.9,0.0456,0,0,0.5,1.5
ENSMUSG00000020003,PEX7,peroxisomal biogenesis factor 7,intracellular|cell|cytoplasm|peroxisome|peroxisomal matrix|cytosol|cytosol|,neuron migration|endochondral ossification|protein targeting to peroxisome|fatty acid beta-oxidation|transport|peroxisome organization|ether lipid biosynthetic process|protein transport|protein import into peroxisome matrix|protein import into peroxisome matrix|,peroxisome matrix targeting signal-2 binding|enzyme binding|protein homodimerization activity|,10,1,27.6,10,0.3,3.18,0.8,26.8,26.8,0.0462,0,0,0.4,1.7
ENSMUSG00000025868,HIGD2A,"HIG1 domain family, member 2A",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|negative regulation of apoptotic process|oxidation-reduction process|mitochondrial respiratory chain supercomplex assembly|,molecular_function|,10,-0.6,13.4,10,-0.7,14.1,-0.7,26.8,-26.8,0.0462,0,0,-1,-0.4
ENSMUSG00000050244,HEATR1,HEAT repeat containing 1,nucleus|nucleolus|mitochondrion|membrane|,biological_process|,poly(A) RNA binding|,5,1.1,15.8,4,0.8,12.1,0.9,26.8,26.8,0.0462,0,0,0.6,1.8
ENSMUSG00000027636,SLA2,Src-like-adaptor 2,cytoplasm|endosome|late endosome|plasma membrane|membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|,negative regulation of transcription from RNA polymerase II promoter|immune system process|positive regulation of signal transduction|positive regulation of signal transduction|T cell activation|negative regulation of calcium-mediated signaling|,SH3/SH2 adaptor activity|SH3/SH2 adaptor activity|protein binding|protein N-terminus binding|,10,1.8,25.7,10,0.8,3.07,1.7,25.9,25.9,0.0513,0,0,0.9,2.9
ENSMUSG00000033294,NOC4L,nucleolar complex associated 4 homolog (S. cerevisiae),nucleus|nucleolus|membrane|integral component of membrane|,biological_process|ribosome biogenesis|,poly(A) RNA binding|,9,0.7,10.3,8,0.5,16.4,0.7,25.7,25.7,0.0524,0,0,0.4,1.1
ENSMUSG00000027170,EIF3M,"eukaryotic translation initiation factor 3, subunit M","cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex, eIF3m|",cytoplasmic translational initiation|translation|translational initiation|,translation initiation factor activity|translation initiation factor binding|,5,0.8,2.38,8,-1,25.8,-1,25.3,-25.3,0.0552,0,0,-1.7,-0.7
ENSMUSG00000022905,KPNA1,karyopherin (importin) alpha 1,nucleus|cytoplasm|dendrite|,protein import into nucleus|transport|protein transport|positive regulation of protein import into nucleus|,protein binding|protein transporter activity|,10,0.5,7.26,10,0.4,18.3,0.5,24.9,24.9,0.0581,0,0,0.3,0.8
ENSMUSG00000037935,SMARCE1,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1",nuclear chromatin|nucleus|SWI/SNF complex|SWI/SNF complex|transcriptional repressor complex|protein complex|npBAF complex|nBAF complex|,"nucleosome disassembly|chromatin remodeling|nervous system development|metabolic process|chromatin modification|ATP-dependent chromatin remodeling|negative regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|DNA binding|RNA binding|protein binding|N-acetyltransferase activity|ligand-dependent nuclear receptor binding|nucleosomal DNA binding|protein N-terminus binding|,10,0.7,9.08,10,0.6,15.6,0.6,24.2,24.2,0.0635,0,0,0.4,1
ENSMUSG00000047187,RAB2A,"RAB2A, member RAS oncogene family",Golgi membrane|intracellular|cell|nucleus|lysosomal membrane|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|neuronal cell body|extracellular vesicular exosome|,GTP catabolic process|transport|intracellular protein transport|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|,nucleotide binding|GTPase activity|GTP binding|GDP binding|,10,0.8,19.5,10,0.3,9.14,0.6,23.7,23.7,0.0675,0,0,0.3,1
ENSMUSG00000051378,KIF18B,kinesin family member 18B,astral microtubule|nucleus|cytoplasm|cytoskeleton|kinesin complex|microtubule|plasma membrane|microtubule plus-end|,mitotic cell cycle|microtubule-based movement|microtubule depolymerization|cell cycle|mitotic nuclear division|metabolic process|cell division|regulation of cell division|,nucleotide binding|motor activity|microtubule motor activity|ATP binding|microtubule binding|kinesin binding|,10,0.5,7.76,10,0.4,16.3,0.5,23.6,23.6,0.0683,0,0,0.3,0.8
ENSMUSG00000035199,ARL6IP5,ADP-ribosylation factor-like 6 interacting protein 5,cytoplasm|endoplasmic reticulum|cytoskeleton|membrane|integral component of membrane|extracellular vesicular exosome|,intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of mitochondrial membrane potential|L-glutamate transport|positive regulation of stress-activated MAPK cascade|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of transport|,protein binding|protein C-terminus binding|,10,2,22.8,10,0.6,6.11,1.9,23.5,23.5,0.0691,0,0,0.4,4
ENSMUSG00000026887,MRRF,mitochondrial ribosome recycling factor,mitochondrion|,translation|ribosome disassembly|,molecular_function|,10,0.3,0.555,10,1.2,25.6,1.2,23.3,23.3,0.0709,0,0,0.4,2
ENSMUSG00000039427,ALG1,"asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,biological_process|,"molecular_function|chitobiosyldiphosphodolichol beta-mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",9,-0.4,5.89,9,0.7,18,0.8,23,23,0.0736,0,0,0.5,1.3
ENSMUSG00000029048,RER1,RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae),endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|cell surface|membrane|integral component of membrane|integral component of Golgi membrane|,"retrograde vesicle-mediated transport, Golgi to ER|neuromuscular junction development|skeletal muscle acetylcholine-gated channel clustering|positive regulation of establishment of protein localization to plasma membrane|",acetylcholine receptor binding|,10,0.3,1.5,10,1.5,25.7,1.5,22.9,22.9,0.0746,0,0,0.9,3
ENSMUSG00000040940,ARHGEF1,Rho guanine nucleotide exchange factor (GEF) 1,cytoplasm|plasma membrane|membrane|,regulation of Rho protein signal transduction|termination of G-protein coupled receptor signaling pathway|negative regulation of cell death|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|poly(A) RNA binding|,10,-0.3,5.68,10,-0.5,18,-0.4,22.7,-22.7,0.0767,0,0,-0.8,-0.3
ENSMUSG00000020832,ERAL1,Era (G-protein)-like 1 (E. coli),intracellular|cytoplasm|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|actin cytoskeleton|membrane|intermediate filament cytoskeleton|,ribosomal small subunit assembly|ribosome biogenesis|,nucleotide binding|RNA binding|GTP binding|rRNA binding|ribosomal small subunit binding|poly(A) RNA binding|,9,0.6,10.7,9,0.9,12.9,0.8,22.7,22.7,0.0767,0,0,0.5,1.4
ENSMUSG00000031153,GRIPAP1,GRIP1 associated protein 1,endosome|blood microparticle|,None,protein binding|,9,0.8,10.3,9,0.7,12.6,0.7,22.5,22.5,0.0787,0,0,0.4,1.1
ENSMUSG00000070953,RABEPK,Rab9 effector protein with kelch motifs,cytoplasm|endosome|plasma membrane|membrane|intracellular membrane-bounded organelle|,None,None,10,0.6,12.2,10,0.5,10.7,0.5,22.3,22.3,0.0809,0,0,0.3,0.9
ENSMUSG00000036769,WDR44,WD repeat domain 44,cytoplasm|endosome|Golgi apparatus|microtubule|membrane|perinuclear region of cytoplasm|,regulation of cell migration|,Rab GTPase binding|,10,-0.6,5.34,10,1.1,21.8,1.1,22.1,22.1,0.0834,0,0,0.2,1.8
ENSMUSG00000038070,CNTLN,"centlein, centrosomal protein",cytoplasm|cytoplasm|centriole|cytoskeleton|extracellular vesicular exosome|,centriole-centriole cohesion|protein localization to organelle|,"protein kinase binding|protein domain specific binding|protein binding, bridging|",10,0.1,0.368,10,1.5,25,1.5,21.9,21.9,0.0858,0,0,1,3
ENSMUSG00000001909,TRMT1,tRNA methyltransferase 1,cellular_component|,tRNA processing|biological_process|methylation|,tRNA binding|RNA binding|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|transferase activity|poly(A) RNA binding|metal ion binding|,10,0.6,8.01,10,0.6,14.3,0.6,21.9,21.9,0.0858,0,0,0.4,1
ENSMUSG00000025209,PEO1,progressive external ophthalmoplegia 1 (human),mitochondrion|mitochondrion|mitochondrial nucleoid|,DNA replication|mitochondrial DNA replication|mitochondrial DNA replication|DNA unwinding involved in DNA replication|transcription from mitochondrial promoter|DNA duplex unwinding|protein hexamerization|protein homooligomerization|,nucleotide binding|protease binding|DNA helicase activity|DNA helicase activity|single-stranded DNA binding|helicase activity|ATP binding|hydrolase activity|5'-3' DNA helicase activity|,10,0.8,14.6,9,0.4,10.6,0.6,21.7,21.7,0.0883,0,0,0.3,1.1
ENSMUSG00000029221,SLC30A9,"solute carrier family 30 (zinc transporter), member 9",nucleus|cytoplasm|cytoskeleton|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|ion transport|cation transport|zinc ion transport|positive regulation of transcription from RNA polymerase II promoter|transmembrane transport|regulation of RNA biosynthetic process|",chromatin binding|cation transmembrane transporter activity|ligand-dependent nuclear receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|,10,-0.3,2.97,10,-2.1,24.2,-2.1,21.5,-21.5,0.0907,0,0,-4,-1.7
ENSMUSG00000000131,XPO6,exportin 6,nucleus|nucleolus|cytoplasm|plasma membrane|,protein export from nucleus|transport|intracellular protein transport|protein transport|,Ran GTPase binding|protein transporter activity|,10,-0.6,11.7,10,-0.5,10.2,-0.6,21.2,-21.2,0.0946,0,0,-0.9,-0.3
ENSMUSG00000026037,ORC2,"origin recognition complex, subunit 2",chromatin|heterochromatin|origin recognition complex|condensed chromosome inner kinetochore|nucleus|nuclear origin of replication recognition complex|nuclear origin of replication recognition complex|plasma membrane|membrane|,DNA replication|,DNA replication origin binding|,10,0.1,0.147,10,-1.5,23.7,-1.5,20.8,-20.8,0.0999,0,0,-3,-0.7
ENSMUSG00000020283,PEX13,peroxisomal biogenesis factor 13,peroxisome|peroxisome|peroxisomal membrane|peroxisomal membrane|integral component of peroxisomal membrane|membrane|membrane|integral component of membrane|,"fatty acid alpha-oxidation|neuron migration|suckling behavior|transport|locomotory behavior|protein transport|protein import into peroxisome matrix, docking|protein import into peroxisome matrix, docking|cerebral cortex cell migration|microtubule-based peroxisome localization|",peroxisome targeting sequence binding|,10,0.3,3.06,10,0.6,19.1,0.6,20.8,20.8,0.0999,0,0,0.4,1.1
ENSMUSG00000027601,MTFR1,mitochondrial fission regulator 1,cytoplasm|mitochondrion|mitochondrion|plasma membrane|,aerobic respiration|,None,10,-0.3,2.62,10,1.4,23.7,1.4,20.7,20.7,0.101,0,0,0.9,2
ENSMUSG00000033365,IPO13,importin 13,nucleus|cytoplasm|,glucocorticoid receptor import into nucleus|protein import into nucleus|transport|intracellular protein transport|protein transport|,Ran GTPase binding|glucocorticoid receptor binding|,10,0.7,20.6,9,-1.3,13.6,0.6,20.7,20.7,0.101,0,0,0.3,1.4
ENSMUSG00000019774,MTRF1L,mitochondrial translational release factor 1-like,cytoplasm|mitochondrion|mitochondrion|,translation|translational termination|,"molecular_function|translation release factor activity|translation release factor activity, codon specific|",10,0.9,16.2,10,0.4,6.81,0.6,20.7,20.7,0.101,0,0,0.3,1.2
ENSMUSG00000027255,ARFGAP2,ADP-ribosylation factor GTPase activating protein 2,nucleolus|cytoplasm|Golgi apparatus|plasma membrane|membrane|,transport|protein transport|vesicle-mediated transport|regulation of ARF GTPase activity|,GTPase activator activity|ARF GTPase activator activity|zinc ion binding|metal ion binding|,10,-0.4,1.66,10,1.6,24.2,1.6,20.7,20.7,0.101,0,0,1.3,3
ENSMUSG00000032066,BCO2,beta-carotene oxygenase 2,intracellular|mitochondrion|,carotenoid metabolic process|carotene metabolic process|carotene metabolic process|carotene catabolic process|carotene catabolic process|retinoic acid metabolic process|retinal metabolic process|regulation of mitochondrial membrane potential|oxidation-reduction process|oxidation-reduction process|regulation of reactive oxygen species metabolic process|,"oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|metal ion binding|dioxygenase activity|",10,-0.1,0.29,10,1.4,24,1.4,20.6,20.6,0.102,0,0,0.9,2
ENSMUSG00000036435,EXOC1,exocyst complex component 1,membrane|,transport|exocytosis|biological_process|protein transport|,molecular_function|,10,1.3,10.4,10,0.5,11.8,0.7,20.4,20.4,0.105,0,0,0.4,1.4
ENSMUSG00000025224,GBF1,golgi-specific brefeldin A-resistance factor 1,mitochondrion|peroxisome|endoplasmic reticulum lumen|Golgi apparatus|Golgi stack|cis-Golgi network|trans-Golgi network|membrane|,vesicle-mediated transport|positive regulation of GTPase activity|,ARF guanyl-nucleotide exchange factor activity|protein binding|,10,-1.2,23.8,10,0.5,6.65,-1.2,20.4,-20.4,0.105,0,0,-2,-0.9
ENSMUSG00000001445,MRPL10,mitochondrial ribosomal protein L10,mitochondrion|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,ribosome biogenesis|,structural constituent of ribosome|poly(A) RNA binding|,10,1,12.2,10,0.9,8.36,0.9,20,20,0.112,0,0,0.4,1.6
ENSMUSG00000010914,PDHX,"pyruvate dehydrogenase complex, component X",mitochondrion|,metabolic process|,"transferase activity, transferring acyl groups|",10,-0.5,12.9,10,-0.6,7.09,-0.5,19.6,-19.6,0.118,0,0,-0.9,-0.3
ENSMUSG00000025580,EIF4A3,eukaryotic translation initiation factor 4A3,nucleus|nucleus|cytoplasm|membrane|exon-exon junction complex|catalytic step 2 spliceosome|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|ATP catabolic process|negative regulation of translation|positive regulation of translation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of mRNA splicing, via spliceosome|embryonic cranial skeleton morphogenesis|",mRNA binding|ATP-dependent RNA helicase activity|ATP binding|poly(A) binding|poly(A) RNA binding|,7,1.6,19.5,7,-0.8,3.11,1.5,19.6,19.6,0.118,0,0,0.7,2.5
ENSMUSG00000020946,GOSR2,golgi SNAP receptor complex member 2,Golgi membrane|endoplasmic reticulum membrane|Golgi apparatus|Golgi stack|membrane|membrane|integral component of membrane|,transport|protein transport|vesicle-mediated transport|,None,10,1,9.48,10,0.8,10.5,0.9,19.4,19.4,0.122,0,0,0.6,1.7
ENSMUSG00000040034,NUP43,nucleoporin 43,"chromosome, centromeric region|kinetochore|nucleus|nuclear pore|chromosome|nuclear pore outer ring|",transport|cell cycle|chromosome segregation|mitotic nuclear division|protein transport|mRNA transport|cell division|,molecular_function|,8,1,12.8,8,0.5,8.11,0.7,19.4,19.4,0.122,0,0,0.3,1.5
ENSMUSG00000022407,ADSL,adenylosuccinate lyase,mitochondrion|cytosol|,purine nucleotide metabolic process|purine nucleotide biosynthetic process|AMP biosynthetic process|AMP biosynthetic process|response to nutrient|metabolic process|aerobic respiration|purine ribonucleotide biosynthetic process|ribonucleoside monophosphate biosynthetic process|protein tetramerization|,"catalytic activity|N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity|N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity|lyase activity|(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity|",7,0.5,3.15,8,1,18,0.9,19.2,19.2,0.125,0,0,0.5,1.7
ENSMUSG00000037772,MRPL23,mitochondrial ribosomal protein L23,intracellular|nucleolus|mitochondrion|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,nucleotide binding|structural constituent of ribosome|,9,0.4,1.55,10,0.7,19,0.6,18.8,18.8,0.133,0,0,0.4,1.1
ENSMUSG00000003438,TIMM50,translocase of inner mitochondrial membrane 50,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane presequence translocase complex|membrane|integral component of membrane|nuclear speck|,release of cytochrome c from mitochondria|protein dephosphorylation|transport|mitochondrial membrane organization|protein transport|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|interleukin-2 receptor binding|ribonucleoprotein complex binding|,10,0.8,11.9,10,-1.4,20.1,-1.3,18,-18,0.146,0,0,-2,-0.2
ENSMUSG00000045100,SLC25A26,"solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|S-adenosyl-L-methionine transport|transmembrane transport|S-adenosyl-L-methionine transmembrane transport|,S-adenosyl-L-methionine transmembrane transporter activity|,10,0.7,7.97,10,1,11.6,0.8,17.9,17.9,0.147,0,0,0.4,1.5
ENSMUSG00000024797,VPS51,vacuolar protein sorting 51 homolog (S. cerevisiae),GARP complex|Golgi apparatus|,"transport|lipid transport|autophagy|protein transport|retrograde transport, endosome to Golgi|",molecular_function|,9,-0.4,2.06,8,-1.4,19.1,-1.3,17.7,-17.7,0.15,0,0,-2,-0.4
ENSMUSG00000034206,POLQ,"polymerase (DNA directed), theta",None,ATP catabolic process|DNA replication|DNA-dependent DNA replication|DNA repair|DNA repair|DNA biosynthetic process|,DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|single-stranded DNA-dependent ATPase activity|,10,0.4,4.03,10,0.5,13.9,0.5,17.5,17.5,0.153,0,0,0.3,0.9
ENSMUSG00000043702,PDE12,phosphodiesterase 12,mitochondrion|,mRNA processing|biological_process|,"molecular_function|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|photoreceptor cyclic-nucleotide phosphodiesterase activity|nuclease activity|exonuclease activity|poly(A)-specific ribonuclease activity|hydrolase activity|7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity|metal ion binding|inositol phosphosphingolipid phospholipase activity|inositol phosphorylceramide phospholipase activity|mannosyl-inositol phosphorylceramide phospholipase activity|mannosyl-diinositol phosphorylceramide phospholipase activity|",10,-0.5,10.3,10,-0.3,7.83,-0.5,17.3,-17.3,0.155,0,0,-0.8,-0.2
ENSMUSG00000096141,DNAH7A,"dynein, axonemal, heavy chain 7A",cilium|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0.9,6.39,10,1.1,11.5,1,17,17,0.159,0,0,0.6,1.9
ENSMUSG00000032101,DDX25,DEAD (Asp-Glu-Ala-Asp) box polypeptide 25,nucleus|nucleus|cytoplasm|cytoplasm|chromatoid body|,ATP catabolic process|ATP catabolic process|mRNA export from nucleus|regulation of translation|transport|multicellular organismal development|spermatogenesis|spermatid development|cell differentiation|mRNA transport|,nucleotide binding|nucleic acid binding|RNA binding|RNA helicase activity|ATP-dependent RNA helicase activity|helicase activity|ATP binding|hydrolase activity|ATPase activity|,10,0.7,12.1,10,0.5,5.88,0.6,16.9,16.9,0.16,0,0,0.3,1.3
ENSMUSG00000032288,IMP3,"IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)",intracellular|nucleus|nucleolus|nucleolus|ribonucleoprotein complex|,rRNA processing|ribosome biogenesis|,RNA binding|rRNA binding|snoRNP binding|poly(A) RNA binding|,6,-1.2,19.3,6,0.3,0.799,-1.1,16.7,-16.7,0.162,0,0,-2,-0.5
ENSMUSG00000038011,DNAH10,"dynein, axonemal, heavy chain 10",axonemal dynein complex|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|,10,-0.2,1.46,10,1.1,19.9,1.1,16.6,16.6,0.163,0,0,0.4,2
ENSMUSG00000014301,PAM16,presequence translocase-asssociated motor 16 homolog (S. cerevisiae),cytoplasm|mitochondrion|mitochondrial inner membrane|,DNA biosynthetic process|negative regulation of apoptotic signaling pathway|,molecular_function|,7,0.6,9.82,7,-1,8.87,0.6,16.6,16.6,0.163,0,0,0.3,1.1
ENSMUSG00000025858,GET4,golgi to ER traffic protein 4 homolog (S. cerevisiae),cytoplasm|cytosol|BAT3 complex|,transport|tail-anchored membrane protein insertion into ER membrane|,molecular_function|,10,0.2,1.26,10,0.5,16.6,0.5,16.4,16.4,0.165,0,0,0.3,0.9
ENSMUSG00000022313,UTP23,"UTP23, small subunit (SSU) processome component, homolog (yeast)",cellular_component|nucleus|small-subunit processome|,rRNA processing|biological_process|ribosome biogenesis|,poly(A) RNA binding|,9,0.6,10.8,9,0.9,5.83,0.8,15.6,15.6,0.175,0,0,0.3,1.3
ENSMUSG00000024091,VAPA,"vesicle-associated membrane protein, associated protein A",endoplasmic reticulum|endoplasmic reticulum|plasma membrane|tight junction|microtubule cytoskeleton|membrane|integral component of membrane|vesicle|perinuclear region of cytoplasm|,signal transduction|cell death|neuron projection development|positive regulation of I-kappaB kinase/NF-kappaB signaling|protein localization to endoplasmic reticulum|,signal transducer activity|structural molecule activity|protein heterodimerization activity|,10,0.6,5.09,10,0.5,10.9,0.5,15.5,15.5,0.176,0,0,0.3,0.9
ENSMUSG00000001417,RHBG,Rhesus blood group-associated B glycoprotein,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|spectrin-associated cytoskeleton|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|cytoplasmic vesicle|anchored component of plasma membrane|,transport|organic cation transport|ammonium transport|ammonium transport|transepithelial ammonium transport|ammonium transmembrane transport|ammonium transmembrane transport|,ammonium transmembrane transporter activity|ammonium transmembrane transporter activity|ankyrin binding|,10,1.1,10.5,10,1,5.33,1,15.4,15.4,0.177,0,0,0.7,2
ENSMUSG00000023041,KRT6B,keratin 6B,intermediate filament|extracellular vesicular exosome|,morphogenesis of an epithelium|keratinization|intermediate filament organization|,None,10,-0.1,0.329,10,0.6,17.4,0.5,15.3,15.3,0.178,0,0,0.3,1
ENSMUSG00000026645,OLAH,oleoyl-ACP hydrolase,cellular_component|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|biosynthetic process|,"molecular_function|oleoyl-[acyl-carrier-protein] hydrolase activity|myristoyl-[acyl-carrier-protein] hydrolase activity|palmitoyl-[acyl-carrier-protein] hydrolase activity|acyl-[acyl-carrier-protein] hydrolase activity|hydrolase activity|hydrolase activity, acting on ester bonds|",10,1.3,17,10,0.3,2.39,1.2,15.1,15.1,0.181,0,0,0.3,1.9
ENSMUSG00000051391,YWHAG,"tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide",intracellular|cell|cytoplasm|membrane|membrane-bounded vesicle|extracellular vesicular exosome|,protein targeting|cellular response to insulin stimulus|regulation of neuron differentiation|regulation of synaptic plasticity|oxidation-reduction process|,monooxygenase activity|protein kinase C binding|insulin-like growth factor receptor binding|protein binding|oxidoreductase activity|protein domain specific binding|receptor tyrosine kinase binding|poly(A) RNA binding|,10,0.5,6.85,10,0.4,8.56,0.5,14.9,14.9,0.183,0,0,0.2,0.9
ENSMUSG00000010406,MRPL52,mitochondrial ribosomal protein L52,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,9,-0.4,4.91,9,0.7,14.3,0.7,14.9,14.9,0.183,0,0,0.3,1.4
ENSMUSG00000028861,MRPS15,mitochondrial ribosomal protein S15,intracellular|mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|nuclear membrane|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,10,1.2,17.4,10,-0.4,1.27,1.2,14.9,14.9,0.183,0,0,0.5,1.9
ENSMUSG00000068697,MYOZ1,myozenin 1,nucleus|actin cytoskeleton|actin cytoskeleton|cell projection|,None,protein binding|FATZ binding|,10,-1.1,16.3,10,-0.4,1.34,-0.9,14.9,-14.9,0.183,0,0,-1.9,-0.3
ENSMUSG00000033213,AA467197,expressed sequence AA467197,nucleus|mitochondrion|,biological_process|,molecular_function|,10,1.2,18,10,-0.2,1.19,1.2,14.8,14.8,0.185,0,0,0.7,2
ENSMUSG00000037933,BICD2,bicaudal D homolog 2 (Drosophila),intracellular|cell|cytoplasm|Golgi apparatus|Golgi apparatus|cytoskeleton|plasma membrane|cytoplasmic vesicle|,transport|microtubule-based movement|minus-end-directed organelle transport along microtubule|microtubule anchoring at microtubule organizing center|,protein binding|Rab GTPase binding|,10,0.2,1.01,10,0.4,14.3,0.4,14.7,14.7,0.186,0,0,0.2,0.8
ENSMUSG00000024683,MRPL16,mitochondrial ribosomal protein L16,mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|rRNA binding|,10,0.8,7.69,10,0.8,7.31,0.8,14.6,14.6,0.187,0,0,0.4,1.4
ENSMUSG00000037531,MRPL47,mitochondrial ribosomal protein L47,mitochondrion|mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,translation|biological_process|,molecular_function|structural constituent of ribosome|,8,0.7,9.44,8,0.7,5.51,0.7,14.6,14.6,0.187,0,0,0.4,1.3
ENSMUSG00000021243,FCF1,FCF1 small subunit (SSU) processome component homolog (S. cerevisiae),cellular_component|nucleus|small-subunit processome|,rRNA processing|biological_process|ribosome biogenesis|,poly(A) RNA binding|,9,1.1,14,9,-1.1,8.21,0.7,14.5,14.5,0.188,0,0,0.3,1.8
ENSMUSG00000021076,ACTR10,ARP10 actin-related protein 10,cytoplasm|cytoskeleton|dynactin complex|,microtubule-based movement|,protein binding|,10,-0.6,3.54,9,0.6,17.1,0.6,14.4,14.4,0.189,0,0,0.3,1.3
ENSMUSG00000009995,TAZ,tafazzin,nucleus|mitochondrion|cytosol|membrane|,muscle contraction|heart development|skeletal muscle tissue development|hemopoiesis|cardiolipin biosynthetic process|mitochondrial respiratory chain complex I assembly|cristae formation|mitochondrial ATP synthesis coupled electron transport|phosphatidylglycerol metabolic process|cardiac muscle tissue development|cardiac muscle contraction|,1-acylglycerophosphocholine O-acyltransferase activity|,10,-1.1,14.6,10,-0.2,4.23,-0.3,14.2,-14.2,0.192,0,0,-1.7,-0.2
ENSMUSG00000029319,COQ2,"coenzyme Q2 homolog, prenyltransferase (yeast)",mitochondrion|membrane|integral component of membrane|,glycerol metabolic process|ubiquinone biosynthetic process|isoprenoid biosynthetic process|biosynthetic process|,4-hydroxybenzoate decaprenyltransferase activity|prenyltransferase activity|transferase activity|4-hydroxybenzoate nonaprenyltransferase activity|,10,0.5,4.49,10,1,11,0.9,14.1,14.1,0.193,0,0,0.2,1.6
ENSMUSG00000020628,TRAPPC12,trafficking protein particle complex 12,cellular_component|,transport|biological_process|vesicle-mediated transport|,molecular_function|,10,0.2,1.03,10,0.4,14,0.4,13.9,13.9,0.196,0,0,0.2,0.8
ENSMUSG00000022706,MRPL40,mitochondrial ribosomal protein L40,nucleolus|mitochondrion|mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,biological_process|,poly(A) RNA binding|,8,0.4,3.27,8,0.9,13,0.8,13.8,13.8,0.197,0,0,0.3,1.4
ENSMUSG00000020477,MRPS24,mitochondrial ribosomal protein S24,mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,biological_process|,structural constituent of ribosome|poly(A) RNA binding|,10,0.7,12.3,9,0.4,3.42,0.6,13.5,13.5,0.2,0,0,0.3,1.2
ENSMUSG00000002930,PPP1R17,"protein phosphatase 1, regulatory subunit 17",cytosol|,regulation of phosphatase activity|negative regulation of catalytic activity|negative regulation of catalytic activity|,protein phosphatase inhibitor activity|protein serine/threonine phosphatase inhibitor activity|phosphatase inhibitor activity|,10,1.2,16.5,10,-0.5,5.53,1,13.4,13.4,0.202,0,0,0.6,1.9
ENSMUSG00000018819,LSP1,lymphocyte specific 1,plasma membrane|membrane|membrane|extracellular vesicular exosome|,apoptotic process|chemotaxis|defense response|cytoskeleton organization|signal transduction|,actin binding|signal transducer activity|,10,1.2,16,10,-0.2,1.9,1.1,13.4,13.4,0.202,0,0,0.4,2
ENSMUSG00000022427,TOMM22,translocase of outer mitochondrial membrane 22 homolog (yeast),mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane translocase complex|mitochondrial inner membrane|membrane|membrane|integral component of membrane|,transport|intracellular protein transport|protein transport|protein import into mitochondrial outer membrane|,protein binding|protein transmembrane transporter activity|,10,1,13.3,10,-0.3,4.56,0.7,13.4,13.4,0.202,0,0,0.2,1.7
ENSMUSG00000037149,DDX1,DEAD (Asp-Glu-Ala-Asp) box polypeptide 1,nucleus|cytoplasm|cytoplasmic stress granule|cytoplasmic stress granule|membrane|ribonucleoprotein complex|cleavage body|tRNA-splicing ligase complex|,"ATP catabolic process|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|response to virus|DNA duplex unwinding|response to exogenous dsRNA|nucleic acid phosphodiester bond hydrolysis|regulation of RNA biosynthetic process|",nucleotide binding|nucleic acid binding|DNA binding|chromatin binding|transcription cofactor activity|RNA binding|double-stranded RNA binding|helicase activity|nuclease activity|exonuclease activity|protein binding|ATP binding|ATP-dependent helicase activity|poly(A) binding|hydrolase activity|DNA/RNA helicase activity|poly(A) RNA binding|,10,1.5,5.43,10,0.7,10.2,0.8,13.2,13.2,0.204,0,0,0.4,1.9
ENSMUSG00000016833,MRPS18C,mitochondrial ribosomal protein S18C,intracellular|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,10,0.2,1.19,10,0.7,14.2,0.7,13.1,13.1,0.205,0,0,0.3,1.3
ENSMUSG00000051811,COX6B2,cytochrome c oxidase subunit VIb polypeptide 2,mitochondrion|mitochondrial crista|,biological_process|,molecular_function|cytochrome-c oxidase activity|,9,1.2,15.6,9,0.2,0.427,1.1,12.9,12.9,0.208,0,0,0.3,2
ENSMUSG00000029916,AGK,acylglycerol kinase,mitochondrion|mitochondrion|membrane|intracellular membrane-bounded organelle|,protein kinase C-activating G-protein coupled receptor signaling pathway|metabolic process|phosphorylation|ceramide biosynthetic process|lipid phosphorylation|,nucleotide binding|lipid kinase activity|ceramide kinase activity|NAD+ kinase activity|diacylglycerol kinase activity|ATP binding|kinase activity|transferase activity|acylglycerol kinase activity|,10,-0.6,6.79,10,-0.5,6.83,-0.6,12.9,-12.9,0.208,0,0,-1.1,-0.3
ENSMUSG00000044763,TRMT10C,tRNA methyltransferase 10C,nucleus|mitochondrion|mitochondrion|mitochondrial nucleoid|,mitochondrial RNA 5'-end processing|tRNA processing|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,0.6,8.19,9,-0.7,6.37,0.6,12.8,12.8,0.209,0,0,0.3,1.2
ENSMUSG00000035948,ACSS3,acyl-CoA synthetase short-chain family member 3,mitochondrion|,biological_process|metabolic process|,nucleotide binding|molecular_function|catalytic activity|acetate-CoA ligase activity|ATP binding|ligase activity|,10,1.2,15.6,10,0.2,1.11,1.1,12.8,12.8,0.209,0,0,0.2,1.9
ENSMUSG00000005069,PEX5,peroxisomal biogenesis factor 5,intracellular|intracellular|cell|cytoplasm|mitochondrion|peroxisome|peroxisomal membrane|peroxisomal membrane|peroxisomal matrix|Golgi apparatus|cytosol|cytosol|membrane|protein complex|,"very long-chain fatty acid metabolic process|neuron migration|protein targeting to peroxisome|protein targeting to peroxisome|protein targeting to peroxisome|fatty acid beta-oxidation|transport|mitochondrion organization|mitochondrial membrane organization|endoplasmic reticulum organization|peroxisome organization|peroxisome organization|protein transport|protein import into peroxisome matrix|protein import into peroxisome matrix|protein import into peroxisome matrix|protein import into peroxisome matrix, docking|protein import into peroxisome matrix, docking|protein import into peroxisome matrix, translocation|cerebral cortex cell migration|cerebral cortex neuron differentiation|positive regulation of multicellular organism growth|cellular lipid metabolic process|protein import into peroxisome membrane|cell development|neuromuscular process|protein tetramerization|negative regulation of protein homotetramerization|",peroxisome targeting sequence binding|peroxisome targeting sequence binding|peroxisome matrix targeting signal-1 binding|peroxisome matrix targeting signal-1 binding|peroxisome matrix targeting signal-1 binding|protein C-terminus binding|protein C-terminus binding|enzyme binding|small GTPase binding|protein N-terminus binding|,10,0.6,9.25,10,0.4,4.46,0.5,12.8,12.8,0.209,0,0,0.2,0.9
ENSMUSG00000037805,RPL10A,ribosomal protein L10A,nucleus|nucleolus|cytoplasm|mitochondrion|ribosome|large ribosomal subunit|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,RNA binding|structural constituent of ribosome|poly(A) RNA binding|,7,0.9,4.26,6,0.6,9.31,0.6,12.7,12.7,0.21,0,0,0.3,1.5
ENSMUSG00000033852,PLA2G4B,"phospholipase A2, group IVB (cytosolic)",cytoplasm|cytosol|membrane|cytoplasmic vesicle|,lipid metabolic process|metabolic process|phospholipid catabolic process|lipid catabolic process|glycerophospholipid catabolic process|,phospholipase activity|lysophospholipase activity|phospholipase A2 activity|hydrolase activity|metal ion binding|calcium-dependent phospholipase A2 activity|,10,1,12,10,0.3,3.14,0.6,12.7,12.7,0.21,0,0,0.2,1.6
ENSMUSG00000035629,1700021K19RIK,RIKEN cDNA 1700021K19 gene,lysosome|endosome|early endosome|late endosome|,endocytosis|autophagy|negative regulation of autophagy|negative regulation of endocytosis|,molecular_function|,10,0.4,7.09,10,0.3,5.97,0.4,12.6,12.6,0.212,0,0,0.2,0.8
ENSMUSG00000036291,AP5M1,"adaptor-related protein complex 5, mu 1 subunit",cytoplasm|lysosome|endosome|late endosome|cytosol|membrane|AP-type membrane coat adaptor complex|clathrin adaptor complex|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|endosomal transport|,None,10,-0.4,8.15,10,-0.3,4.68,-0.4,12.4,-12.4,0.215,0,0,-0.8,-0.2
ENSMUSG00000070372,CAPZA1,"capping protein (actin filament) muscle Z-line, alpha 1",cytoplasm|cytoskeleton|cell-cell junction|F-actin capping protein complex|membrane|cortical cytoskeleton|extracellular vesicular exosome|WASH complex|,actin cytoskeleton organization|barbed-end actin filament capping|actin filament capping|,actin binding|protein binding|protein binding|actin filament binding|,10,0.3,4.68,10,0.5,8.94,0.4,12.3,12.3,0.216,0,0,0.2,0.8
ENSMUSG00000073643,WDFY1,WD repeat and FYVE domain containing 1,nucleus|early endosome|cytosol|,biological_process|,1-phosphatidylinositol binding|metal ion binding|,10,0.3,2.82,10,0.4,9.66,0.4,12.1,12.1,0.219,0,0,0.2,0.7
ENSMUSG00000058006,MDN1,midasin homolog (yeast),nucleus|nucleolus|cytoplasm|membrane|intermediate filament cytoskeleton|,biological_process|,nucleotide binding|molecular_function|ATP binding|,9,1.7,7.34,9,0.8,8.74,1.5,11.9,11.9,0.222,0,0,0.6,2.7
ENSMUSG00000019143,HARS2,"histidyl-tRNA synthetase 2, mitochondrial (putative)",cytoplasm|mitochondrion|,translation|tRNA aminoacylation for protein translation|histidyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA ligase activity|histidine-tRNA ligase activity|ATP binding|ligase activity|poly(A) RNA binding|,8,1.4,12.8,8,0.4,2.52,1.3,11.8,11.8,0.223,0,0,0.7,2
ENSMUSG00000030879,MRPL17,mitochondrial ribosomal protein L17,intracellular|mitochondrion|mitochondrial inner membrane|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,mitochondrial genome maintenance|translation|,structural constituent of ribosome|protein domain specific binding|,9,-0.8,1.65,9,0.8,14.8,0.8,11.8,11.8,0.223,0,0,0.3,1.6
ENSMUSG00000006169,CLINT1,clathrin interactor 1,nucleus|cytoplasm|Golgi apparatus|membrane|membrane|clathrin-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|,endocytosis|clathrin coat assembly|,lipid binding|clathrin binding|,10,0.5,8.7,10,0.3,4.21,0.4,11.8,11.8,0.223,0,0,0.2,0.8
ENSMUSG00000041842,FHDC1,FH2 domain containing 1,cellular_component|,biological_process|,molecular_function|,10,1.4,7.54,10,0.6,8.01,0.7,11.8,11.8,0.223,0,0,0.4,2
ENSMUSG00000026568,MPC2,mitochondrial pyruvate carrier 2,intracellular|cell|nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,pyruvate metabolic process|transport|mitochondrial pyruvate transport|,pyruvate transmembrane transporter activity|,10,-0.3,3.16,10,-0.3,8.93,-0.3,11.7,-11.7,0.225,0,0,-0.6,-0.2
ENSMUSG00000030168,ADIPOR2,adiponectin receptor 2,plasma membrane|plasma membrane|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|hormone-mediated signaling pathway|fatty acid oxidation|negative regulation of cell growth|adiponectin-activated signaling pathway|adiponectin-activated signaling pathway|positive regulation of glucose import|,receptor activity|hormone binding|hormone binding|identical protein binding|protein heterodimerization activity|adiponectin binding|,10,0,0,10,1.1,13.6,1,11.7,11.7,0.225,0,0,0.3,2
ENSMUSG00000029480,DHX37,DEAH (Asp-Glu-Ala-His) box polypeptide 37,cellular_component|,biological_process|,nucleotide binding|helicase activity|ATP binding|hydrolase activity|,9,0.5,4.86,9,0.4,7.44,0.4,11.6,11.6,0.226,0,0,0.2,1.1
ENSMUSG00000041258,ZFP236,zinc finger protein 236,cellular_component|,biological_process|,molecular_function|,9,-0.9,14.6,9,0.2,1.18,-0.9,11.4,-11.4,0.229,0,0,-1.8,-0.5
ENSMUSG00000028420,TMEM38B,transmembrane protein 38B,nucleus|endoplasmic reticulum|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|monovalent inorganic cation transport|potassium ion transmembrane transport|,cation channel activity|potassium channel activity|,9,0.3,1.62,9,0.4,10.1,0.3,11.3,11.3,0.231,0,0,0.2,0.7
ENSMUSG00000025981,COQ10B,coenzyme Q10 homolog B (S. cerevisiae),mitochondrion|mitochondrial inner membrane|membrane|,biological_process|,molecular_function|,10,-0.8,14.5,10,0.3,8.49,-0.8,11.3,-11.3,0.231,0,0,-2,0.2
ENSMUSG00000042705,COMMD10,COMM domain containing 10,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.491,10,-0.5,12.4,-0.4,11,-11,0.235,0,0,-1,-0.2
ENSMUSG00000069184,ZFP72,zinc finger protein 72,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.5,0.722,10,-0.5,10.4,-0.5,10.9,-10.9,0.237,0,0,-1,-0.2
ENSMUSG00000050043,TMX2,thioredoxin-related transmembrane protein 2,cellular_component|,biological_process|,molecular_function|,9,1.4,11.5,8,0.4,2.83,1.1,10.7,10.7,0.24,0,0,0.3,2.2
ENSMUSG00000008035,MID1IP1,Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)),nucleus|cytoplasm|cytosol|cytoskeleton|microtubule|microtubule cytoskeleton|,lipid metabolic process|negative regulation of microtubule depolymerization|positive regulation of fatty acid biosynthetic process|regulation of lipid biosynthetic process|protein polymerization|positive regulation of ligase activity|,protein binding|protein C-terminus binding|,10,-0.4,6.68,10,-0.2,5.03,-0.3,10.6,-10.6,0.242,0,0,-0.7,-0.1
ENSMUSG00000047635,2810006K23RIK,RIKEN cDNA 2810006K23 gene,cellular_component|mitochondrion|,translation|translational termination|biological_process|,molecular_function|translation release factor activity|,9,-0.4,5.96,9,-0.5,4.99,-0.4,10.5,-10.5,0.244,0,0,-1.4,-0.1
ENSMUSG00000041203,2310036O22RIK,RIKEN cDNA 2310036O22 gene,cellular_component|,biological_process|,molecular_function|,9,0.3,0.993,9,0.5,10.1,0.4,10.4,10.4,0.245,0,0,0.2,1
ENSMUSG00000000568,HNRNPD,heterogeneous nuclear ribonucleoprotein D,nucleus|cytoplasm|cytosol|virion|viral nucleocapsid|ribonucleoprotein complex|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of circadian rhythm|regulation of mRNA stability|positive regulation of translation|mRNA stabilization|rhythmic process|circadian regulation of translation|",nucleotide binding|nucleic acid binding|DNA binding|RNA binding|protein binding|telomeric DNA binding|poly(A) RNA binding|,10,-0.5,2.94,10,0.4,10.5,0.4,10.4,10.4,0.245,0,0,0.2,1
ENSMUSG00000036632,ALG5,asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase),endoplasmic reticulum|membrane|membrane|integral component of membrane|,determination of left/right symmetry|,"dolichyl-phosphate beta-glucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.4,4.49,10,0.3,6.49,0.3,10.4,10.4,0.245,0,0,0.2,0.7
ENSMUSG00000017631,ABR,active BCR-related gene,intracellular|cytosol|plasma membrane|membrane|,signal transduction|brain development|actin cytoskeleton organization|negative regulation of cell migration|response to lipopolysaccharide|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|inner ear morphogenesis|negative regulation of neutrophil degranulation|positive regulation of GTPase activity|negative regulation of inflammatory response|positive regulation of phagocytosis|neuromuscular process controlling balance|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|Rac GTPase activator activity|Rac GTPase activator activity|,10,-0.3,3.2,10,-0.3,7.32,-0.3,10.2,-10.2,0.249,0,0,-0.7,-0.1
ENSMUSG00000027433,XRN2,5'-3' exoribonuclease 2,nucleus|nucleus|nucleolus|membrane|aggresome|,"DNA catabolic process, exonucleolytic|nucleobase-containing compound metabolic process|DNA repair|DNA recombination|transcription, DNA-templated|DNA-templated transcription, termination|regulation of transcription, DNA-templated|mRNA processing|microtubule-based process|cell growth|RNA metabolic process|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|nucleic acid binding|nuclease activity|exonuclease activity|5'-3' exoribonuclease activity|protein binding|zinc ion binding|5'-3' exonuclease activity|hydrolase activity|poly(A) RNA binding|metal ion binding|,9,0.3,1.56,10,1,11.2,0.4,10.1,10.1,0.251,0,0,0.1,1.7
ENSMUSG00000020111,MICU1,mitochondrial calcium uptake 1,mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|mitochondrial intermembrane space|membrane|integral component of mitochondrial membrane|calcium channel complex|uniplex complex|,transport|ion transport|calcium ion transport|mitochondrial calcium ion transport|calcium ion import into mitochondrion|protein homooligomerization|mitochondrial calcium ion homeostasis|positive regulation of mitochondrial calcium ion concentration|calcium ion import|,calcium ion binding|calcium ion binding|protein binding|metal ion binding|protein heterodimerization activity|protein heterodimerization activity|,10,1.2,13.4,10,-0.5,2.15,1.1,10,10,0.253,0,0,0.3,2
ENSMUSG00000024414,MRPL27,mitochondrial ribosomal protein L27,intracellular|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,1.3,8.94,10,0.3,6.88,0.4,9.97,9.97,0.253,0,0,0.2,1.7
ENSMUSG00000008683,RPS15A,ribosomal protein S15A,cytoplasm|mitochondrion|membrane|cytosolic small ribosomal subunit|extracellular vesicular exosome|,positive regulation of cell proliferation|response to virus|positive regulation of cell cycle|,structural constituent of ribosome|poly(A) RNA binding|,6,-0.9,3.38,5,0.9,9.55,0.8,9.75,9.75,0.258,0,0,0.3,1.9
ENSMUSG00000032621,SREK1,splicing regulatory glutamine/lysine-rich protein 1,nucleus|spliceosomal complex|mitochondrion|intracellular membrane-bounded organelle|,mRNA processing|biological_process|RNA splicing|,nucleotide binding|nucleic acid binding|poly(A) RNA binding|,10,0.4,2.34,10,0.3,7.65,0.3,9.62,9.62,0.26,0,0,0.1,0.7
ENSMUSG00000038982,BLOC1S5,"biogenesis of lysosomal organelles complex-1, subunit 5, muted",intracellular|cell|transport vesicle|BLOC-1 complex|BLOC-1 complex|,anterograde axon cargo transport|vesicle-mediated transport|neuron projection development|melanosome transport|otolith morphogenesis|endosome to melanosome transport|developmental pigmentation|anterograde synaptic vesicle transport|positive regulation of pigment cell differentiation|,protein binding|,10,0.9,5.65,10,0.5,5.41,0.6,9.56,9.56,0.261,0,0,0.2,1.5
ENSMUSG00000019863,QRSL1,glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1,mitochondrion|glutamyl-tRNA(Gln) amidotransferase complex|,translation|mitochondrial translation|glutaminyl-tRNAGln biosynthesis via transamidation|,"nucleotide binding|ATP binding|ligase activity|carbon-nitrogen ligase activity, with glutamine as amido-N-donor|glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity|",9,0.3,0.815,9,1,11.2,1,9.53,9.53,0.262,0,0,0.1,2
ENSMUSG00000030037,MRPL53,mitochondrial ribosomal protein L53,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,10,0.1,0.106,10,0.8,12.1,0.8,9.39,9.39,0.265,0,0,0.5,1.9
ENSMUSG00000027424,MGME1,mitochondrial genome maintainance exonuclease 1,mitochondrion|mitochondrion|,"mitochondrial genome maintenance|DNA catabolic process, exonucleolytic|mitochondrial DNA replication|mitochondrial DNA replication|DNA repair|cellular response to DNA damage stimulus|mitochondrial DNA repair|",nuclease activity|exonuclease activity|single-stranded DNA exodeoxyribonuclease activity|single-stranded DNA exodeoxyribonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,0,0,10,1,11.9,1,9.34,9.34,0.266,0,0,0.1,1.7
ENSMUSG00000051169,RPUSD3,RNA pseudouridylate synthase domain containing 3,cellular_component|,pseudouridine synthesis|RNA modification|,RNA binding|pseudouridine synthase activity|poly(A) RNA binding|,10,-0.4,6.3,10,-0.5,3.31,-0.4,9.21,-9.21,0.269,0,0,-0.9,-0.1
ENSMUSG00000030780,BC017158,cDNA sequence BC017158,membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.5,5.82,10,0.6,3.46,0.6,8.92,8.92,0.275,0,0,0.2,1.2
ENSMUSG00000066235,POMGNT2,"protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2",endoplasmic reticulum|membrane|integral component of membrane|,protein O-linked glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|protein O-GlcNAc transferase activity|",10,-0.6,7.38,10,-1.2,4.57,-1.1,8.89,-8.89,0.276,0,0,-1.8,-0.3
ENSMUSG00000025982,SF3B1,"splicing factor 3b, subunit 1",nucleus|nucleus|spliceosomal complex|U12-type spliceosomal complex|intracellular membrane-bounded organelle|catalytic step 2 spliceosome|,"RNA splicing, via transesterification reactions|mRNA splicing, via spliceosome|mRNA processing|RNA splicing|anterior/posterior pattern specification|",chromatin binding|protein binding|poly(A) RNA binding|,9,-0.9,10.2,9,0.6,10.1,0.5,8.88,8.88,0.276,0,0,-1.6,1.9
ENSMUSG00000034037,FGD5,"FYVE, RhoGEF and PH domain containing 5",cellular_component|cytoplasm|endosome|endoplasmic reticulum|Golgi apparatus|cytoskeleton|plasma membrane|membrane|cell projection|,biological_process|regulation of Rho protein signal transduction|,molecular_function|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|metal ion binding|,10,-0.3,0.869,10,0.3,9.83,0.3,8.59,8.59,0.283,0,0,0.1,0.8
ENSMUSG00000049760,2410015M20RIK,RIKEN cDNA 2410015M20 gene,mitochondrion|,biological_process|,molecular_function|,10,1,3.61,10,0.8,5.84,0.9,8.57,8.57,0.284,0,0,-0.1,2
ENSMUSG00000042426,DHX29,DEAH (Asp-Glu-Ala-His) box polypeptide 29,cytoplasm|mitochondrion|eukaryotic 43S preinitiation complex|,translation|translational initiation|biological_process|,nucleotide binding|nucleic acid binding|translation initiation factor activity|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|ribosomal small subunit binding|poly(A) RNA binding|,10,0.2,2.28,10,0.5,8.26,0.4,8.43,8.43,0.287,0,0,-0.5,1.3
ENSMUSG00000026798,COQ4,coenzyme Q4 homolog (yeast),mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,ubiquinone biosynthetic process|biological_process|,molecular_function|,10,0.1,0.425,10,0.9,11.1,0.8,8.4,8.4,0.288,0,0,0.4,1.9
ENSMUSG00000024181,MRPL28,mitochondrial ribosomal protein L28,intracellular|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,10,0.5,5.21,9,0.3,4.31,0.4,8.38,8.38,0.288,0,0,0.1,1
ENSMUSG00000040824,SNRPD2,small nuclear ribonucleoprotein D2,nucleus|spliceosomal complex|U1 snRNP|U4 snRNP|U12-type spliceosomal complex|cytoplasm|cytosol|virion|viral nucleocapsid|ribonucleoprotein complex|small nuclear ribonucleoprotein complex|methylosome|pICln-Sm protein complex|SMN-Sm protein complex|extracellular vesicular exosome|catalytic step 2 spliceosome|,spliceosomal snRNP assembly|mRNA processing|RNA splicing|,poly(A) RNA binding|,7,0.5,3.16,6,0.8,6.08,0.6,8.32,8.32,0.29,0,0,0.1,2
ENSMUSG00000062981,MRPL42,mitochondrial ribosomal protein L42,mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|plasma membrane|ribonucleoprotein complex|,biological_process|,poly(A) RNA binding|,10,0.4,2.31,10,0.7,6.5,0.7,8.21,8.21,0.293,0,0,0.1,2
ENSMUSG00000057541,PUS7,pseudouridylate synthase 7 homolog (S. cerevisiae),cellular_component|,biological_process|,enzyme binding|poly(A) RNA binding|,10,0.4,5.16,10,0.3,3.81,0.3,8.21,8.21,0.293,0,0,0.1,0.8
ENSMUSG00000015023,DDX19A,DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a,nucleus|nuclear pore|cytoplasm|membrane|membrane|,transport|protein transport|positive regulation of apoptotic process|mRNA transport|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|hydrolase activity|,9,0.5,6.01,9,0.3,3.99,0.3,8.19,8.19,0.293,0,0,0.1,0.9
ENSMUSG00000013662,ATAD1,"ATPase family, AAA domain containing 1",mitochondrion|peroxisome|peroxisomal membrane|plasma membrane|membrane|membrane|cell junction|synapse|postsynaptic membrane|,"positive regulation of receptor internalization|ATP catabolic process|learning|memory|negative regulation of synaptic transmission, glutamatergic|",nucleotide binding|protein binding|ATP binding|hydrolase activity|ATPase activity|,10,-0.1,0.487,10,-0.3,8.55,-0.3,8.11,-8.11,0.295,0,0,-0.8,-0.1
ENSMUSG00000044957,PP2D1,protein phosphatase 2C-like domain containing 1,cellular_component|,biological_process|,molecular_function|catalytic activity|,10,-1,11,10,-0.1,0.417,-1,8.07,-8.07,0.297,0,0,-1.9,-0.2
ENSMUSG00000016619,NUP50,nucleoporin 50,intracellular|cell|nucleus|nuclear pore|nuclear pore|ribonucleoprotein complex|nuclear membrane|,neural tube formation|nucleocytoplasmic transport|,nucleocytoplasmic transporter activity|protein binding|,10,1.3,10.5,10,0.2,3.51,1.3,8.03,8.03,0.298,0,0,0.3,2
ENSMUSG00000034226,RHOV,"ras homolog gene family, member V",cellular_component|intracellular|endosome|plasma membrane|membrane|,signal transduction|small GTPase mediated signal transduction|,nucleotide binding|GTP binding|metal ion binding|,10,0.4,6.53,10,0.3,1.96,0.4,8.02,8.02,0.298,0,0,0.1,0.9
ENSMUSG00000052962,MRPL35,mitochondrial ribosomal protein L35,intracellular|mitochondrion|ribosome|ribonucleoprotein complex|,translation|biological_process|,molecular_function|structural constituent of ribosome|,10,-0.7,8.07,10,0.8,2.46,0.7,7.75,7.75,0.306,0,0,-1.1,2
ENSMUSG00000012535,TNPO3,transportin 3,nucleus|cytoplasm|intracellular membrane-bounded organelle|,transport|protein transport|splicing factor protein import into nucleus|,molecular_function|,7,0.2,0.567,7,0.9,9.12,0.8,7.68,7.68,0.308,0,0,0.3,1.9
ENSMUSG00000037363,LETM2,leucine zipper-EF-hand containing transmembrane protein 2,cellular_component|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.5,6.41,10,0.3,1.95,0.4,7.64,7.64,0.309,0,0,0.1,1.1
ENSMUSG00000049134,NRAP,nebulin-related anchoring protein,fascia adherens|muscle tendon junction|myofibril|,actin cytoskeleton organization|,actin binding|protein binding|zinc ion binding|vinculin binding|metal ion binding|muscle alpha-actinin binding|,10,0.1,0.0928,10,0.9,9.38,0.8,7.55,7.55,0.311,0,0,0.4,2
ENSMUSG00000078919,DPM1,dolichol-phosphate (beta-D) mannosyltransferase 1,nucleus|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|dolichol-phosphate-mannose synthase complex|intracellular membrane-bounded organelle|,GPI anchor biosynthetic process|GPI anchor biosynthetic process|dolichol metabolic process|dolichol metabolic process|GDP-mannose metabolic process|protein mannosylation|protein O-linked mannosylation|mannosylation|,dolichyl-phosphate-mannose-protein mannosyltransferase activity|dolichyl-phosphate beta-D-mannosyltransferase activity|dolichyl-phosphate beta-D-mannosyltransferase activity|mannose binding|alcohol binding|,1,0.8,3.89,1,0.6,4.19,0.7,7.53,7.53,0.312,0,0,0.4,2
ENSMUSG00000019763,RMND1,required for meiotic nuclear division 1 homolog (S. cerevisiae),mitochondrion|mitochondrion|,translation|biological_process|,molecular_function|,10,-0.3,2.73,10,-0.4,5.43,-0.4,7.5,-7.5,0.312,0,0,-1,-0.1
ENSMUSG00000058267,MRPS14,mitochondrial ribosomal protein S14,intracellular|mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|nuclear membrane|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,9,0.3,1.02,9,0.4,7.11,0.3,7.46,7.46,0.314,0,0,0.1,1.1
ENSMUSG00000027420,BFSP1,"beaded filament structural protein 1, in lens-CP94",cytoplasm|cytoplasm|mitochondrion|cytoskeleton|intermediate filament|plasma membrane|actin cytoskeleton|membrane|,cell maturation|lens fiber cell development|,structural molecule activity|structural constituent of eye lens|protein binding|,10,-0.2,0.901,10,1,10.7,1,7.41,7.41,0.315,0,0,0.2,2
ENSMUSG00000020709,ADAP2,ArfGAP with dual PH domains 2,cytoplasm|mitochondrial envelope|cytosol|plasma membrane|membrane|,heart development|regulation of ARF GTPase activity|inositol lipid-mediated signaling|,"GTPase activator activity|1-phosphatidylinositol binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|ARF GTPase activator activity|zinc ion binding|phosphatidylinositol-3,4-bisphosphate binding|inositol 1,3,4,5 tetrakisphosphate binding|metal ion binding|",10,0,0,10,0.4,9.27,0.4,7.3,7.3,0.319,0,0,0,1.2
ENSMUSG00000032643,FHL3,four and a half LIM domains 3,stress fiber|nucleus|Z disc|,actin cytoskeleton organization|,actin binding|protein binding|zinc ion binding|metal ion binding|,10,0.1,0.095,10,0.4,8.78,0.4,7.28,7.28,0.319,0,0,0,1.2
ENSMUSG00000074211,SDHAF1,succinate dehydrogenase complex assembly factor 1,mitochondrion|mitochondrion|,mitochondrial respiratory chain complex II assembly|,molecular_function|,3,0.8,4.91,3,0.4,3.56,0.6,7.12,7.12,0.324,0,0,0.2,1.9
ENSMUSG00000079025,GSDMC,gasdermin C,cytoplasm|mitochondrion|microtubule organizing center|,biological_process|,molecular_function|,10,0.4,3.23,10,0.5,4.22,0.5,7.1,7.1,0.325,0,0,0.1,1.3
ENSMUSG00000038838,VARS2,"valyl-tRNA synthetase 2, mitochondrial (putative)",mitochondrion|,translation|tRNA aminoacylation for protein translation|valyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA editing activity|aminoacyl-tRNA ligase activity|valine-tRNA ligase activity|ATP binding|ligase activity|,8,-0.3,1.27,8,0.4,7.67,0.4,7.1,7.1,0.325,0,0,-0.4,1.1
ENSMUSG00000025555,FARP1,"FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)",cytoplasm|cytosol|cytoskeleton|plasma membrane|membrane|extrinsic component of membrane|cell junction|dendrite|extrinsic component of cytoplasmic side of plasma membrane|cell projection|neuron projection|synapse|,multicellular organismal development|synapse assembly|negative regulation of phosphatase activity|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|dendrite morphogenesis|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|cytoskeletal protein binding|Rac guanyl-nucleotide exchange factor activity|Rac GTPase binding|,10,-0.6,5.87,10,-0.2,1.99,-0.5,6.92,-6.92,0.331,0,0,-1.5,0.3
ENSMUSG00000038013,WIPF2,"WAS/WASL interacting protein family, member 2",cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|actin binding|,10,1.1,8.33,10,0.4,0.518,0.6,6.86,6.86,0.333,0,0,0.2,1.9
ENSMUSG00000040029,IPO8,importin 8,nucleus|cytoplasm|integral component of plasma membrane|,ATP catabolic process|transport|intracellular protein transport|protein transport|transmembrane transport|,"Ran GTPase binding|ATPase activity, coupled to transmembrane movement of substances|",10,-0.2,2.59,10,-0.3,4.5,-0.3,6.76,-6.76,0.336,0,0,-0.7,0
ENSMUSG00000035248,ZCCHC6,"zinc finger, CCHC domain containing 6",cellular_component|,RNA 3'-end processing|,nucleic acid binding|zinc ion binding|transferase activity|nucleotidyltransferase activity|poly(A) RNA binding|metal ion binding|RNA uridylyltransferase activity|,10,-0.3,5.13,10,-0.3,1.79,-0.3,6.62,-6.62,0.342,0,0,-0.9,0.1
ENSMUSG00000026784,PDSS1,"prenyl (solanesyl) diphosphate synthase, subunit 1",mitochondrion|,ubiquinone biosynthetic process|ubiquinone biosynthetic process|isoprenoid biosynthetic process|isoprenoid biosynthetic process|protein heterotetramerization|,trans-hexaprenyltranstransferase activity|trans-hexaprenyltranstransferase activity|transferase activity|metal ion binding|protein heterodimerization activity|protein heterodimerization activity|trans-octaprenyltranstransferase activity|,10,0.2,1.87,10,0.5,6.02,0.5,6.61,6.61,0.342,0,0,0,1.5
ENSMUSG00000079614,SEH1L,SEH1-like (S. cerevisiae,"chromosome, centromeric region|kinetochore|nucleus|nuclear pore|chromosome|nuclear pore outer ring|",cytokine production involved in inflammatory response|transport|nuclear pore organization|cell cycle|chromosome segregation|mitotic nuclear division|mitotic metaphase plate congression|protein transport|defense response to Gram-positive bacterium|mRNA transport|cell division|attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|,molecular_function|,9,0.3,2.23,10,0.6,5.42,0.5,6.6,6.6,0.342,0,0,-0.9,1.4
ENSMUSG00000003955,FAM162A,"family with sequence similarity 162, member A",nucleus|cytoplasm|mitochondrion|mitochondrion|membrane|integral component of membrane|extracellular vesicular exosome|,apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|transformed cell apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|neuron apoptotic process|neuron apoptotic process|cellular response to hypoxia|cellular response to hypoxia|positive regulation of release of cytochrome c from mitochondria|positive regulation of release of cytochrome c from mitochondria|,molecular_function|,10,-1.4,9.87,10,-0.1,0.589,-1.3,6.51,-6.51,0.346,0,0,-2,-0.5
ENSMUSG00000025362,RPS26,ribosomal protein S26,nucleolus|cytoplasm|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|extracellular vesicular exosome|,negative regulation of RNA splicing|,mRNA binding|poly(A) RNA binding|,5,0.6,3.53,5,0.9,4.08,0.8,6.44,6.44,0.348,0,0,-0.7,2
ENSMUSG00000027485,BPIFB1,"BPI fold containing family B, member 1",extracellular region|extracellular space|extracellular vesicular exosome|,innate immune response in mucosa|immune system process|negative regulation of toll-like receptor 4 signaling pathway|innate immune response|,lipid binding|,10,-1,6.06,10,-0.6,2.1,-0.8,6.42,-6.42,0.349,0,0,-2,-0.3
ENSMUSG00000028386,SLC46A2,"solute carrier family 46, member 2",plasma membrane|cell surface|membrane|integral component of membrane|,transport|T cell homeostasis|regulation of T cell differentiation|thymus development|transmembrane transport|negative regulation of T cell apoptotic process|,molecular_function|transporter activity|,10,0.4,0.995,10,0.3,5.66,0.3,6.36,6.36,0.352,0,0,0,1
ENSMUSG00000029036,ATAD3A,"ATPase family, AAA domain containing 3A",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial nucleoid|,cell growth|negative regulation of apoptotic process|,nucleotide binding|molecular_function|ATP binding|,6,0.7,3.52,5,0.4,4.04,0.4,6.34,6.34,0.353,0,0,0.1,1.7
ENSMUSG00000057388,MRPL18,mitochondrial ribosomal protein L18,extracellular space|mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,transport|rRNA import into mitochondrion|,RNA binding|5S rRNA binding|,10,-0.1,0.0187,10,0.7,9.07,0.7,6.28,6.28,0.355,0,0,-0.9,2
ENSMUSG00000022412,MIEF1,mitochondrial elongation factor 1,mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,mitochondrial fission|positive regulation of mitochondrial fission|positive regulation of mitochondrial fission|,nucleotide binding|GDP binding|identical protein binding|ADP binding|,10,0.6,4.43,10,0.4,2.34,0.5,6.26,6.26,0.355,0,0,0.1,1.4
ENSMUSG00000056293,GSDMC2,gasdermin C2,cytoplasm|mitochondrion|microtubule organizing center|,biological_process|,molecular_function|,10,0,0,10,0.3,6.87,0.3,6.25,6.25,0.356,0,0,0,0.9
ENSMUSG00000071528,USMG5,upregulated during skeletal muscle growth 5,mitochondrion|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,4,-0.6,2.74,4,0.8,4.84,0.8,6.23,6.23,0.357,0,0,-0.8,2
ENSMUSG00000032803,CDV3,carnitine deficiency-associated gene expressed in ventricle 3,nucleolus|cytoplasm|cytoplasm|,biological_process|,molecular_function|,10,-0.3,0.996,10,-0.3,5.47,-0.3,6.21,-6.21,0.357,0,0,-1,0
ENSMUSG00000031916,COG8,component of oligomeric golgi complex 8,Golgi apparatus|membrane|membrane|Golgi transport complex|,transport|biological_process|protein transport|,molecular_function|,8,0.4,3.3,8,0.6,3.79,0.4,6.19,6.19,0.358,0,0,-0.3,1.4
ENSMUSG00000059434,GCKR,glucokinase regulatory protein,intracellular|cell|nucleus|nucleus|nucleoplasm|cytoplasm|mitochondrion|cytosol|,"protein import into nucleus, translocation|protein import into nucleus, translocation|cellular glucose homeostasis|carbohydrate metabolic process|response to fructose|negative regulation of glucokinase activity|negative regulation of glucokinase activity|positive regulation of glucokinase activity|protein localization to nucleus|negative regulation of catalytic activity|urate metabolic process|triglyceride homeostasis|",enzyme inhibitor activity|enzyme binding|protein domain specific binding|carbohydrate binding|fructose-6-phosphate binding|,10,0.3,1.76,10,0.4,4.67,0.4,6.08,6.08,0.363,0,0,-0.2,1.4
ENSMUSG00000062257,OPCML,opioid binding protein/cell adhesion molecule-like,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.3,3.48,10,-0.2,2.92,-0.3,6.08,-6.08,0.363,0,0,-0.8,0.1
ENSMUSG00000054312,MRPS21,mitochondrial ribosomal protein S21,mitochondrion|mitochondrial inner membrane|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,9,-0.9,6.45,10,0.5,3.07,-0.8,6.08,-6.08,0.363,0,0,-2,0.6
ENSMUSG00000033557,FAM20B,"family with sequence similarity 20, member B",Golgi apparatus|membrane|integral component of membrane|,phosphorylation|,"nucleotide binding|ATP binding|phosphofructokinase activity|phosphorylase kinase regulator activity|cobinamide kinase activity|phytol kinase activity|kinase activity|phosphatidylinositol phosphate kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|phenol kinase activity|cyclin-dependent protein kinase activating kinase regulator activity|inositol tetrakisphosphate 2-kinase activity|heptose 7-phosphate kinase activity|aminoglycoside phosphotransferase activity|phosphatidylinositol 3-kinase activity|eukaryotic elongation factor-2 kinase regulator activity|eukaryotic elongation factor-2 kinase activator activity|LPPG:FO 2-phospho-L-lactate transferase activity|cytidine kinase activity|glycerate 2-kinase activity|(S)-lactate 2-kinase activity|phosphoserine:homoserine phosphotransferase activity|L-seryl-tRNA(Sec) kinase activity|phosphocholine transferase activity|polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide kinase activity|GTP-dependent polynucleotide kinase activity|farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|geraniol kinase activity|geranylgeraniol kinase activity|CTP:geranylgeraniol kinase activity|prenol kinase activity|1-phosphatidylinositol-5-kinase activity|1-phosphatidylinositol-3-phosphate 4-kinase activity|phosphatidylinositol-3,4-bisphosphate 5-kinase activity|phosphatidylinositol bisphosphate kinase activity|inositol-3,4,6-trisphosphate 1-kinase activity|inositol 5-diphosphate pentakisphosphate 5-kinase activity|inositol diphosphate tetrakisphosphate kinase activity|",10,0,0,10,0.3,6.85,0.3,6.07,6.07,0.363,0,0,-0.1,0.8
ENSMUSG00000024381,BIN1,bridging integrator 1,nucleus|cytoplasm|synaptic vesicle|Z disc|T-tubule|axon|I band|node of Ranvier|axon initial segment|varicosity|axon terminus|cerebellar mossy fiber|lipid tube|,endocytosis|multicellular organismal development|regulation of endocytosis|cell differentiation|muscle cell differentiation|positive regulation of apoptotic process|positive regulation of GTPase activity|regulation of neuron differentiation|positive regulation of endocytosis|positive regulation of astrocyte differentiation|lipid tube assembly|regulation of cell cycle arrest|,protein binding|protein complex binding|identical protein binding|protein heterodimerization activity|tau protein binding|GTPase binding|,10,-0.3,4.05,10,-0.2,2.38,-0.3,5.97,-5.97,0.367,0,0,-1.1,0.1
ENSMUSG00000038072,GALNT11,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11,cellular_component|Golgi apparatus|membrane|integral component of membrane|,Notch signaling pathway|protein O-linked glycosylation via threonine|,"polypeptide N-acetylgalactosaminyltransferase activity|Notch binding|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-0.3,2.04,10,-0.3,4.19,-0.3,5.93,-5.93,0.369,0,0,-1,0
ENSMUSG00000069844,SCO1,SCO cytochrome oxidase deficient homolog 1 (yeast),mitochondrion|mitochondrial inner membrane|myofibril|,copper ion transport|cellular copper ion homeostasis|biological_process|respiratory chain complex IV assembly|,molecular_function|copper ion binding|metal ion binding|,9,0.3,2.49,9,0.5,4.36,0.5,5.91,5.91,0.369,0,0,-0.7,1.3
ENSMUSG00000094724,RNASET2B,ribonuclease T2B,extracellular space|lysosome|endoplasmic reticulum lumen|extracellular vesicular exosome|,RNA phosphodiester bond hydrolysis|,ribonuclease activity|,10,0.4,3.21,10,0.8,4.25,0.3,5.87,5.87,0.371,0,0,0.1,1.5
ENSMUSG00000023912,SLC25A27,"solute carrier family 25, member 27",mitochondrion|mitochondrion|membrane|integral component of membrane|neuronal cell body|apical part of cell|,transport|positive regulation of cell proliferation|negative regulation of mitochondrial membrane potential|cellular triglyceride homeostasis|negative regulation of apoptotic process|regulation of glucose import|negative regulation of mitochondrial calcium ion concentration|neuron death|,molecular_function|,10,0.1,0.347,10,0.3,5.93,0.3,5.8,5.8,0.374,0,0,-0.1,0.9
ENSMUSG00000020437,MYO1G,myosin IG,plasma membrane|membrane|membrane|myosin complex|extracellular vesicular exosome|,biological_process|,nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|,10,0.5,5.84,10,0.2,1.46,0.4,5.79,5.79,0.375,0,0,-0.2,1.5
ENSMUSG00000095687,RNASET2A,ribonuclease T2A,extracellular space|lysosome|endoplasmic reticulum lumen|extracellular vesicular exosome|,RNA phosphodiester bond hydrolysis|,ribonuclease activity|,10,0.4,3.21,10,0.8,4.18,0.3,5.77,5.77,0.376,0,0,0.1,1.5
ENSMUSG00000073702,RPL31,ribosomal protein L31,intracellular|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,structural constituent of ribosome|poly(A) RNA binding|,7,-0.6,6.24,7,0.2,2.85,-0.4,5.63,-5.63,0.382,0,0,-1.7,0.9
ENSMUSG00000019214,CHTF18,"CTF18, chromosome transmission fidelity factor 18",nucleus|cytoplasm|membrane|,DNA replication|cell cycle|reciprocal meiotic recombination|male meiosis|spermatogenesis|negative regulation of chromosome segregation|,nucleotide binding|molecular_function|DNA binding|ATP binding|,10,-0.5,0.503,10,0.6,7.59,0.6,5.58,5.58,0.384,0,0,-0.3,1.7
ENSMUSG00000028140,MRPL9,mitochondrial ribosomal protein L9,intracellular|mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,9,-0.3,2.72,10,0.8,3.57,0.8,5.52,5.52,0.387,0,0,-0.3,2
ENSMUSG00000038400,PMEPA1,"prostate transmembrane protein, androgen induced 1",cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,protein binding|WW domain binding|,10,-1.4,8.97,10,0.5,0.976,-1.4,5.52,-5.52,0.387,0,0,-2,0
ENSMUSG00000014551,MRPS25,mitochondrial ribosomal protein S25,mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,biological_process|,structural constituent of ribosome|,10,0.4,3.41,9,-0.9,8.54,-0.8,5.51,-5.51,0.387,0,0,-2,0.5
ENSMUSG00000055184,FAM72A,"family with sequence similarity 72, member A",cytoplasm|mitochondrion|cytosol|membrane|,negative regulation of brain-derived neurotrophic factor-activated receptor activity|positive regulation of apoptotic process|,molecular_function|,9,-0.4,1.48,9,-0.6,4.45,-0.5,5.5,-5.5,0.388,0,0,-1.5,0
ENSMUSG00000028292,RARS2,"arginyl-tRNA synthetase 2, mitochondrial",cytoplasm|mitochondrion|,translation|tRNA aminoacylation for protein translation|arginyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA ligase activity|arginine-tRNA ligase activity|ATP binding|ligase activity|poly(A) RNA binding|,8,1.6,2.57,10,0.5,7.47,0.5,5.49,5.49,0.388,0,0,0.1,2.5
ENSMUSG00000022698,NAA50,"N(alpha)-acetyltransferase 50, NatE catalytic subunit",cytoplasm|cytoplasm|NatA complex|extracellular vesicular exosome|,"N-terminal protein amino acid acetylation|histone H4 acetylation|mitotic sister chromatid cohesion, centromeric|","dihydrolipoamide branched chain acyltransferase activity|peptide alpha-N-acetyltransferase activity|sterol O-acyltransferase activity|protein binding|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|H4 histone acetyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",9,0.3,1.77,8,0.3,3.98,0.3,5.47,5.47,0.389,0,0,-0.4,1.2
ENSMUSG00000060519,TOR3A,"torsin family 3, member A",cytoplasm|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|extracellular vesicular exosome|,ATP catabolic process|chaperone mediated protein folding requiring cofactor|,nucleotide binding|3-dehydroquinate dehydratase activity|protein binding|ATP binding|ATPase activity|,10,0.1,0.442,10,0.3,5.41,0.3,5.44,5.44,0.39,0,0,-0.2,1
ENSMUSG00000054065,PKP3,plakophilin 3,nucleus|plasma membrane|spot adherens junction|cell junction|desmosome|,desmosome assembly|cell adhesion|single organismal cell-cell adhesion|establishment of protein localization to plasma membrane|,protein binding|cell adhesion molecule binding|,10,-0.5,7.98,10,0.1,0.886,-0.4,5.43,-5.43,0.391,0,0,-1.3,0.3
ENSMUSG00000016200,SYT14,synaptotagmin XIV,membrane|integral component of membrane|,biological_process|,phospholipid binding|protein homodimerization activity|protein heterodimerization activity|,10,-1,7.52,10,-0.2,1.11,-0.9,5.39,-5.39,0.392,0,0,-2,0.1
ENSMUSG00000059668,KRT4,keratin 4,nucleus|intermediate filament|cell surface|keratin filament|keratin filament|intermediate filament cytoskeleton|,cytoskeleton organization|embryo development|epithelial cell differentiation|negative regulation of epithelial cell proliferation|,structural molecule activity|protein heterodimerization activity|,10,-0.3,2.39,10,0.4,4.13,0.4,5.32,5.32,0.395,0,0,-0.5,1
ENSMUSG00000038302,LACE1,lactation elevated 1,mitochondrion|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0.3,3.14,10,0.3,2.42,0.3,5.27,5.27,0.397,0,0,0,1
ENSMUSG00000044496,2510039O18RIK,RIKEN cDNA 2510039O18 gene,membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.56,10,0.4,3.98,0.4,5.26,5.26,0.398,0,0,0,1.1
ENSMUSG00000038762,ABCF1,"ATP-binding cassette, sub-family F (GCN20), member 1",nucleus|nuclear envelope|nucleoplasm|cytoplasm|ribosome|membrane|polysomal ribosome|,translational initiation|positive regulation of translation|,nucleotide binding|ATP binding|translation activator activity|ATPase activity|ribosome binding|poly(A) RNA binding|,9,0.3,1.36,9,0.8,6.05,0.6,5.26,5.26,0.398,0,0,0,1.8
ENSMUSG00000034209,RASL10A,"RAS-like, family 10, member A",cellular_component|nucleus|plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0.8,3.63,10,0.4,2.09,0.5,5.2,5.2,0.401,0,0,0,1.6
ENSMUSG00000018008,CYTH4,cytohesin 4,plasma membrane|plasma membrane|membrane|,regulation of cell adhesion|regulation of ARF protein signal transduction|positive regulation of GTPase activity|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|lipid binding|,10,0.2,0.859,10,0.7,5.58,0.6,5.13,5.13,0.404,0,0,-0.1,1.6
ENSMUSG00000034064,POGLUT1,protein O-glucosyltransferase 1,endoplasmic reticulum|endoplasmic reticulum lumen|extracellular vesicular exosome|,protein O-linked glycosylation|protein O-linked glycosylation|regulation of Notch signaling pathway|cardiovascular system development|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|protein xylosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|UDP-glucosyltransferase activity|UDP-glucosyltransferase activity|UDP-xylosyltransferase activity|UDP-xylosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.3,1.2,10,0.4,4.32,0.4,5.12,5.12,0.404,0,0,-0.8,1.2
ENSMUSG00000024533,SPIRE1,spire homolog 1 (Drosophila),intracellular|cell|cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|cell cortex|membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle|cleavage furrow|,transport|protein transport|vesicle-mediated transport|actin cytoskeleton organization|actin cytoskeleton organization|cleavage furrow formation|polar body extrusion after meiotic divisions|intracellular transport|Golgi vesicle transport|establishment of meiotic spindle localization|establishment of meiotic spindle localization|formin-nucleated actin cable assembly|,molecular_function|actin binding|,10,0.1,0.219,10,-0.8,7.87,-0.7,5.1,-5.1,0.405,0,0,-1.9,0.2
ENSMUSG00000015341,GOLGA7,"golgi autoantigen, golgin subfamily a, 7",Golgi membrane|palmitoyltransferase complex|Golgi apparatus|Golgi stack|membrane|intrinsic component of Golgi membrane|extracellular vesicular exosome|,Golgi to plasma membrane transport|peptidyl-L-cysteine S-palmitoylation|Golgi to plasma membrane protein transport|protein stabilization|,molecular_function|,10,1.1,6.79,10,0,0,1,5.1,5.1,0.405,0,0,0.2,2
ENSMUSG00000021772,NKIRAS1,NFKB inhibitor interacting Ras-like protein 1,cellular_component|cytoplasm|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,-0.3,1.62,10,-0.6,4.55,-0.4,5.02,-5.02,0.409,0,0,-1.5,0.2
ENSMUSG00000064068,MTX1,metaxin 1,mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|integral component of membrane|,protein targeting to mitochondrion|transport|protein transport|,None,9,0.7,7.33,10,0.1,0.311,0.6,4.98,4.98,0.411,0,0,0,1.7
ENSMUSG00000022601,RPL24,ribosomal protein L24,ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,ribosomal large subunit assembly|translation|translation|mitotic cell cycle checkpoint|exit from mitosis|optic nerve development|retinal ganglion cell axon guidance|retina development in camera-type eye|,structural constituent of ribosome|poly(A) RNA binding|,7,0.9,7.05,6,-0.2,0.886,0.6,4.92,4.92,0.414,0,0,-0.6,2
ENSMUSG00000031557,PLEKHA2,"pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2",nucleus|cytoplasm|plasma membrane|membrane|protein complex|,positive regulation of cell-matrix adhesion|,fibronectin binding|protein binding|1-phosphatidylinositol binding|lipid binding|PDZ domain binding|laminin binding|,10,-1,3.53,10,0.6,6.96,0.5,4.86,4.86,0.418,0,0,-1.2,2
ENSMUSG00000038240,PDSS2,"prenyl (solanesyl) diphosphate synthase, subunit 2",cytoplasm|mitochondrion|,ubiquinone biosynthetic process|ubiquinone biosynthetic process|isoprenoid biosynthetic process|isoprenoid biosynthetic process|regulation of body fluid levels|protein heterotetramerization|,trans-hexaprenyltranstransferase activity|trans-hexaprenyltranstransferase activity|transferase activity|protein heterodimerization activity|protein heterodimerization activity|trans-octaprenyltranstransferase activity|,10,0.4,2.43,10,0.2,2.84,0.3,4.82,4.82,0.42,0,0,-0.2,1.2
ENSMUSG00000032536,TRAK1,"trafficking protein, kinesin binding 1",nucleus|cytoplasm|mitochondrion|endosome|early endosome|,endosome to lysosome transport|,GABA receptor binding|,10,-0.4,4.71,10,-0.9,2.5,-0.5,4.8,-4.8,0.421,0,0,-1.9,0.1
ENSMUSG00000026827,GPD2,"glycerol phosphate dehydrogenase 2, mitochondrial",mitochondrion|mitochondrial inner membrane|glycerol-3-phosphate dehydrogenase complex|membrane|,glycerol-3-phosphate metabolic process|glycerol-3-phosphate metabolic process|gluconeogenesis|NADH metabolic process|multicellular organism growth|camera-type eye development|oxidation-reduction process|,glycerol-3-phosphate dehydrogenase [NAD+] activity|glycerol-3-phosphate dehydrogenase activity|calcium ion binding|oxidoreductase activity|metal ion binding|sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity|sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity|,10,-0.1,0.296,10,0.5,7.02,0.2,4.71,4.71,0.426,0,0,-0.1,1.4
ENSMUSG00000020415,PTTG1,pituitary tumor-transforming gene 1,nucleus|cytoplasm|,regulation of cell growth|DNA repair|cellular response to DNA damage stimulus|cell cycle|chromosome segregation|mitotic nuclear division|negative regulation of cell proliferation|cellular process|negative regulation of endopeptidase activity|homologous chromosome segregation|chromosome organization|cell division|,cysteine-type endopeptidase inhibitor activity|SH3 domain binding|heat shock protein binding|ribosome binding|,10,0.5,4.78,10,0.6,0.141,0.5,4.7,4.7,0.426,0,0,0,1.4
ENSMUSG00000025157,ZDHHC16,"zinc finger, DHHC domain containing 16",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,apoptotic process|protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.1,0.285,10,0.3,4.99,0.3,4.7,4.7,0.426,0,0,-0.1,1
ENSMUSG00000025016,TM9SF3,transmembrane 9 superfamily member 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.33,10,0.3,3.52,0.3,4.55,4.55,0.434,0,0,-0.2,1.1
ENSMUSG00000030801,KAT8,K(lysine) acetyltransferase 8,histone acetyltransferase complex|kinetochore|nucleus|chromosome|nuclear membrane|MLL1 complex|MSL complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone acetylation|myeloid cell differentiation|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|","histone acetyltransferase activity|transcription factor binding|acetyltransferase activity|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|enzyme binding|methylated histone binding|histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|metal ion binding|histone acetyltransferase activity (H4-K16 specific)|",2,0.4,1.29,3,0.3,3.49,0.3,4.49,4.49,0.438,0,0,-0.5,2
ENSMUSG00000063316,RPL27,ribosomal protein L27,nucleus|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,None,poly(A) RNA binding|,3,0,0,2,0.5,5.55,0.4,4.41,4.41,0.443,0,0,-0.3,2
ENSMUSG00000044042,FMN1,formin 1,nucleus|cytoplasm|cytoskeleton|actin filament|plasma membrane|microtubule cytoskeleton|membrane|cell junction|,kidney development|gene expression|positive regulation of actin filament polymerization|forelimb morphogenesis|hindlimb morphogenesis|actin nucleation|skeletal system morphogenesis|dendrite morphogenesis|dendrite morphogenesis|positive regulation of actin nucleation|positive regulation of focal adhesion assembly|limb development|ureteric bud invasion|,actin binding|protein binding|microtubule binding|SH3 domain binding|,10,1.8,6.6,10,0.5,0.649,1.7,4.39,4.39,0.444,0,0,0.1,3
ENSMUSG00000026860,SH3GLB2,SH3-domain GRB2-like endophilin B2,cytoplasm|,biological_process|,molecular_function|,10,-0.3,2.32,10,0.4,6.73,0.3,4.37,4.37,0.445,0,0,-0.7,1.3
ENSMUSG00000009647,MCU,mitochondrial calcium uniporter,intracellular|cell|mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial inner membrane|calcium channel complex|uniplex complex|,transport|ion transport|calcium ion transport|mitochondrial calcium ion transport|mitochondrial calcium ion transport|calcium-mediated signaling|positive regulation of insulin secretion|protein complex oligomerization|calcium ion import into mitochondrion|glucose homeostasis|mitochondrial calcium ion homeostasis|positive regulation of mitochondrial calcium ion concentration|positive regulation of mitochondrial calcium ion concentration|transmembrane transport|calcium ion transmembrane transport|,calcium channel activity|protein binding|uniporter activity|identical protein binding|,10,0,0,10,0.2,5.09,0.2,4.33,4.33,0.448,0,0,-0.6,1
ENSMUSG00000021216,TUBAL3,"tubulin, alpha-like 3",cytoplasm|cytoskeleton|microtubule|protein complex|,GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,0,0,10,0.4,4.78,0.3,4.3,4.3,0.449,0,0,-0.4,1.3
ENSMUSG00000066952,MYO1H,myosin 1H,myosin complex|,None,nucleotide binding|motor activity|actin binding|ATP binding|,10,0.3,2.58,10,0.2,2.13,0.2,4.28,4.28,0.451,0,0,-0.4,1
ENSMUSG00000029390,TMED2,transmembrane emp24 domain trafficking protein 2,endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|integral component of membrane|COPI-coated vesicle|zymogen granule membrane|intracellular membrane-bounded organelle|,in utero embryonic development|somitogenesis|neural tube closure|embryonic placenta development|heart looping|intracellular protein transport|Golgi organization|positive regulation of gene expression|somite rostral/caudal axis specification|negative regulation of GTPase activity|multicellular organism growth|post-anal tail morphogenesis|protein targeting to plasma membrane|,molecular_function|,10,0.1,0.487,10,0.3,4.62,0.3,4.28,4.28,0.451,0,0,-0.2,1.1
ENSMUSG00000000374,TRAPPC10,trafficking protein particle complex 10,cellular_component|Golgi apparatus|,transport|biological_process|vesicle-mediated transport|,molecular_function|,10,-0.4,2,10,-0.4,2.54,-0.4,4.28,-4.28,0.451,0,0,-1.4,0.4
ENSMUSG00000050967,CREG2,cellular repressor of E1A-stimulated genes 2,extracellular region|endoplasmic reticulum|Golgi apparatus|,biological_process|oxidation-reduction process|,molecular_function|FMN binding|oxidoreductase activity|,10,0.3,2.09,10,0.2,2.78,0.2,4.23,4.23,0.454,0,0,-0.9,1.2
ENSMUSG00000031994,ADAMTS8,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8",extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|,metalloendopeptidase activity|heparin binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0.3,5.69,0.3,4.23,4.23,0.454,0,0,-0.4,1.2
ENSMUSG00000038453,SRCIN1,SRC kinase signaling inhibitor 1,cytoplasm|cytoskeleton|plasma membrane|postsynaptic density|actin cytoskeleton|actin cytoskeleton|membrane|lamellipodium|cell junction|filopodium|axon|dendrite|cell projection|neuron projection|neuronal cell body|synapse|postsynaptic membrane|,exocytosis|negative regulation of cell adhesion|regulation of cell migration|substrate adhesion-dependent cell spreading|negative regulation of protein secretion|regulation of dendritic spine morphogenesis|positive regulation of protein tyrosine kinase activity|negative regulation of protein tyrosine kinase activity|,protein binding|protein kinase binding|protein domain specific binding|,10,0.5,1.11,10,0.4,3.34,0.4,4.2,4.2,0.455,0,0,-0.2,1.4
ENSMUSG00000022656,PVRL3,poliovirus receptor-related 3,plasma membrane|cell-cell junction|cell-cell adherens junction|membrane|integral component of membrane|cell junction|apical junction complex|synapse|postsynaptic membrane|,lens morphogenesis in camera-type eye|cell adhesion|homophilic cell adhesion|fertilization|single organismal cell-cell adhesion|retina morphogenesis in camera-type eye|,protein binding|protein homodimerization activity|cell adhesion molecule binding|,10,0.5,3.42,10,0.3,1.12,0.4,4.18,4.18,0.457,0,0,-0.1,1.6
ENSMUSG00000037375,HHAT,hedgehog acyltransferase,endoplasmic reticulum|membrane|integral component of membrane|,smoothened signaling pathway|multicellular organismal development|protein palmitoylation|,"nucleotide binding|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|GTP binding|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.2,0.382,10,1,5.89,1,4.18,4.18,0.457,0,0,-0.2,2
ENSMUSG00000051329,NUP160,nucleoporin 160,kinetochore|nucleus|nuclear pore|nuclear pore|nuclear pore outer ring|,mRNA export from nucleus|mRNA export from nucleus|transport|protein transport|mRNA transport|,nucleocytoplasmic transporter activity|nucleocytoplasmic transporter activity|,2,0.4,1.85,2,0.3,2.72,0.3,4.16,4.16,0.458,0,0,-0.7,2
ENSMUSG00000039956,MRAP,melanocortin 2 receptor accessory protein,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,positive regulation of cAMP biosynthetic process|protein localization to cell surface|brown fat cell differentiation|,corticotropin hormone receptor binding|type 3 melanocortin receptor binding|type 4 melanocortin receptor binding|type 5 melanocortin receptor binding|type 1 melanocortin receptor binding|,10,0.1,0.345,10,0.5,4.78,0.5,4.16,4.16,0.458,0,0,-1.2,1.5
ENSMUSG00000032403,2300009A05RIK,RIKEN cDNA 2300009A05 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.2,0.675,10,0.3,3.79,0.3,4.15,4.15,0.458,0,0,-0.2,1.2
ENSMUSG00000077450,RAB11B,"RAB11B, member RAS oncogene family",cell|cytoplasm|mitochondrion|endosome|synaptic vesicle|membrane|cytoplasmic membrane-bounded vesicle|cell junction|cytoplasmic vesicle|synapse|phagocytic vesicle|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|,"receptor recycling|GTP catabolic process|GTP catabolic process|transport|small GTPase mediated signal transduction|protein transport|melanosome transport|transferrin transport|insulin secretion involved in cellular response to glucose stimulus|regulation of anion transport|constitutive secretory pathway|regulated secretory pathway|regulated secretory pathway|cellular response to acidity|retrograde transport, endosome to plasma membrane|regulation of protein localization to cell surface|regulation of endocytic recycling|",nucleotide binding|GTPase activity|GTPase activity|protein binding|GTP binding|GTP binding|GDP binding|,10,0.3,2.55,10,0.2,2.28,0.3,4.11,4.11,0.461,0,0,-0.3,1.1
ENSMUSG00000001497,PAX9,paired box 9,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|endoderm development|organ morphogenesis|odontogenesis|regulation of odontogenesis|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|face morphogenesis|cellular response to growth factor stimulus|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.4,3.45,10,-0.3,1.25,-0.3,4.1,-4.1,0.461,0,0,-1.3,0.5
ENSMUSG00000033542,ARHGEF5,Rho guanine nucleotide exchange factor (GEF) 5,None,myeloid dendritic cell chemotaxis|actin cytoskeleton organization|regulation of Rho GTPase activity|positive regulation of Rho GTPase activity|positive regulation of podosome assembly|,guanyl-nucleotide exchange factor activity|protein binding|,10,-0.1,0.00214,10,0.7,5.79,0.2,4.03,4.03,0.466,0,0,-0.1,1.7
ENSMUSG00000052698,TLN2,talin 2,ruffle|cytoplasm|cytoskeleton|plasma membrane|fascia adherens|focal adhesion|actin cytoskeleton|membrane|cell junction|synapse|,cytoskeletal anchoring at plasma membrane|cell adhesion|,actin binding|insulin receptor binding|structural molecule activity|structural constituent of cytoskeleton|,10,0,0,10,0.5,6.13,0.4,4.01,4.01,0.467,0,0,-0.3,1.4
ENSMUSG00000046603,TCAIM,"T cell activation inhibitor, mitochondrial",mitochondrion|mitochondrion|,biological_process|,molecular_function|,10,0.3,2.07,10,0.5,2.23,0.4,3.97,3.97,0.47,0,0,-1,1.2
ENSMUSG00000013155,ENKD1,enkurin domain containing 1,cytoplasmic microtubule|microtubule cytoskeleton|,biological_process|,molecular_function|,10,0.2,1.88,10,0.2,2.31,0.2,3.93,3.93,0.472,0,0,-0.2,1.2
ENSMUSG00000037860,AIM2,absent in melanoma 2,nucleus|cytoplasm|cytoplasm|AIM2 inflammasome complex|AIM2 inflammasome complex|,activation of innate immune response|activation of innate immune response|positive regulation of defense response to virus by host|immune system process|apoptotic process|inflammatory response|negative regulation of NF-kappaB transcription factor activity|positive regulation of protein oligomerization|positive regulation of interleukin-1 beta production|positive regulation of interleukin-1 beta production|positive regulation of interleukin-1 beta production|tumor necrosis factor-mediated signaling pathway|cellular response to interferon-beta|cellular response to drug|innate immune response|interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|positive regulation of NF-kappaB transcription factor activity|pyroptosis|pyroptosis|positive regulation of cysteine-type endopeptidase activity|positive regulation of cysteine-type endopeptidase activity|positive regulation of cysteine-type endopeptidase activity|,DNA binding|double-stranded DNA binding|double-stranded DNA binding|protein binding|identical protein binding|identical protein binding|,10,0.5,3.46,10,0.2,1.11,0.4,3.91,3.91,0.474,0,0,-0.3,1.3
ENSMUSG00000009876,COX4I2,cytochrome c oxidase subunit IV isoform 2,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex IV|membrane|mitochondrial membrane|,oxidation-reduction process|hydrogen ion transmembrane transport|hydrogen ion transmembrane transport|,cytochrome-c oxidase activity|cytochrome-c oxidase activity|,10,0,0,10,0.3,4.21,0.3,3.9,3.9,0.474,0,0,-0.2,1.3
ENSMUSG00000026342,SLC35F5,"solute carrier family 35, member F5",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0.4,2,10,0.2,2.22,0.3,3.86,3.86,0.477,0,0,-0.3,1.2
ENSMUSG00000033705,STARD9,START domain containing 9,nucleus|cytoplasm|cytoskeleton|kinesin complex|microtubule|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|lipid binding|,10,-0.5,4.85,10,0,0,-0.4,3.82,-3.82,0.479,0,0,-1.5,0.3
ENSMUSG00000039539,SGCZ,sarcoglycan zeta,cytoplasm|cytoskeleton|plasma membrane|sarcoglycan complex|membrane|integral component of membrane|,membrane organization|,protein binding|,10,-0.9,2,10,-1.1,2.61,-1,3.82,-3.82,0.479,0,0,-2,0.2
ENSMUSG00000014606,SLC25A11,"solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|,transporter activity|poly(A) RNA binding|,10,0.4,2.71,10,0.5,1.39,0.4,3.76,3.76,0.484,0,0,-0.3,1.6
ENSMUSG00000066278,VPS37B,vacuolar protein sorting 37B (yeast),ESCRT I complex|endosome|membrane|midbody|extracellular vesicular exosome|,transport|protein transport|,molecular_function|,10,0.6,4.25,10,0.2,1.44,0.3,3.76,3.76,0.484,0,0,-0.1,1.4
ENSMUSG00000026848,TOR1B,"torsin family 1, member B",nucleus|nuclear envelope|nuclear envelope|cytoplasm|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|membrane|extracellular vesicular exosome|,ATP catabolic process|endoplasmic reticulum organization|chaperone mediated protein folding requiring cofactor|protein homooligomerization|protein homooligomerization|nuclear membrane organization|,nucleotide binding|protein binding|ATP binding|hydrolase activity|ATPase activity|,10,0.6,5.85,10,0.1,0.234,0.4,3.75,3.75,0.484,0,0,0,1.6
ENSMUSG00000018909,ARRB1,"arrestin, beta 1",chromatin|intracellular|nucleus|cytoplasm|cytosol|cytosol|plasma membrane|coated pit|postsynaptic density|membrane|basolateral plasma membrane|pseudopodium|cytoplasmic vesicle|cell projection|dendritic spine|postsynaptic membrane|,"activation of MAPK activity|negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|G-protein coupled receptor internalization|positive regulation of receptor internalization|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transport|endocytosis|signal transduction|G-protein coupled receptor signaling pathway|phototransduction|regulation of G-protein coupled receptor protein signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|negative regulation of signal transduction|protein transport|protein ubiquitination|negative regulation of protein ubiquitination|positive regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|positive regulation of protein binding|negative regulation of interleukin-6 production|negative regulation of interleukin-8 production|positive regulation of peptidyl-serine phosphorylation|negative regulation of GTPase activity|positive regulation of smooth muscle cell apoptotic process|positive regulation of Rho protein signal transduction|positive regulation of histone acetylation|positive regulation of insulin secretion involved in cellular response to glucose stimulus|follicle-stimulating hormone signaling pathway|stress fiber assembly|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of GTPase activity|positive regulation of transcription from RNA polymerase II promoter|negative regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of histone H4 acetylation|",GTPase activator activity|insulin-like growth factor receptor binding|protein binding|transcription factor binding|estrogen receptor binding|mitogen-activated protein kinase kinase binding|ubiquitin protein ligase binding|alpha-1A adrenergic receptor binding|alpha-1B adrenergic receptor binding|angiotensin receptor binding|follicle-stimulating hormone receptor binding|V2 vasopressin receptor binding|AP-2 adaptor complex binding|clathrin adaptor activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|transcription regulatory region DNA binding|ion channel binding|protein phosphorylated amino acid binding|phosphoprotein binding|,10,-0.1,0.0263,10,0.7,6.53,0.6,3.7,3.7,0.488,0,0,-0.7,1.8
ENSMUSG00000028234,RPS20,ribosomal protein S20,intracellular|cytoplasm|ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,RNA binding|structural constituent of ribosome|poly(A) RNA binding|,7,0,0,6,0.6,5.7,0.5,3.69,3.69,0.489,0,0,-1.1,1.9
ENSMUSG00000028412,SLC44A1,"solute carrier family 44, member 1",mitochondrion|mitochondrial outer membrane|plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|choline transport|ion transmembrane transport|,choline transmembrane transporter activity|,10,0.8,5.06,10,0.2,2.4,0.2,3.69,3.69,0.489,0,0,0,1.7
ENSMUSG00000026492,TFB2M,"transcription factor B2, mitochondrial",mitochondrion|mitochondrial matrix|mitochondrial nucleoid|,"rRNA modification|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|transcription from mitochondrial promoter|transcription initiation from mitochondrial promoter|rRNA methylation|methylation|positive regulation of transcription, DNA-templated|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|transcription cofactor activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.6,5.68,10,0.7,4.71,-0.4,3.67,-3.67,0.49,0,0,-1.5,1.5
ENSMUSG00000002486,TCHP,"trichoplein, keratin filament binding",cytoplasm|mitochondrion|centrosome|cytoskeleton|plasma membrane|membrane|keratin filament|apical cortex|,apoptotic process|negative regulation of cell growth|,molecular_function|,10,0.7,3.97,10,0.3,1.13,0.5,3.62,3.62,0.494,0,0,-0.2,1.7
ENSMUSG00000004843,CHMP2B,charged multivesicular body protein 2B,intracellular|nucleus|cytoplasm|mitochondrion|endosome|membrane|extracellular vesicular exosome|,transport|protein transport|,protein domain specific binding|,10,0.1,0.483,10,0.3,3.55,0.3,3.6,3.6,0.495,0,0,-0.2,1.3
ENSMUSG00000019791,HINT3,histidine triad nucleotide binding protein 3,nucleus|nucleolus|cytoplasm|mitochondrion|extracellular vesicular exosome|,biological_process|,nucleotide binding|catalytic activity|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.6,3.29,10,-0.3,0.722,-0.4,3.57,-3.57,0.497,0,0,-1.7,0.4
ENSMUSG00000040717,IL17RD,interleukin 17 receptor D,nucleus|Golgi apparatus|plasma membrane|membrane|integral component of membrane|,None,metal ion binding|,10,0.1,0.318,10,0.5,4.1,0.2,3.56,3.56,0.498,0,0,-0.5,1.5
ENSMUSG00000030257,SRGAP3,SLIT-ROBO Rho GTPase activating protein 3,intracellular|,signal transduction|,GTPase activator activity|protein binding|,10,-0.2,2.22,10,-0.2,1.57,-0.2,3.56,-3.56,0.498,0,0,-1.1,0.6
ENSMUSG00000068290,DDRGK1,DDRGK domain containing 1,endoplasmic reticulum|,biological_process|,molecular_function|,10,0,0,10,0.4,3.9,0.4,3.54,3.54,0.499,0,0,-0.2,1.5
ENSMUSG00000041977,ARHGEF11,Rho guanine nucleotide exchange factor (GEF) 11,cytoplasm|,"G-protein coupled receptor signaling pathway|Rho protein signal transduction|positive regulation of transcription, DNA-templated|",G-protein coupled receptor binding|guanyl-nucleotide exchange factor activity|protein binding|,10,-0.1,0.202,10,0.3,4.41,0.3,3.5,3.5,0.502,0,0,-0.5,1.3
ENSMUSG00000029254,STAP1,signal transducing adaptor family member 1,nucleus|cytoplasm|mitochondrion|protein complex|,transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of signal transduction|myeloid cell differentiation|,SH3/SH2 adaptor activity|protein binding|,10,-0.5,5.64,10,-0.1,0.277,-0.4,3.49,-3.49,0.503,0,0,-1.5,0.2
ENSMUSG00000002733,PLEKHA3,"pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3",Golgi apparatus|membrane|,None,phospholipid binding|1-phosphatidylinositol binding|lipid binding|,10,0,0,10,0.3,4.19,0.3,3.48,3.48,0.504,0,0,-0.3,1.3
ENSMUSG00000004561,METTL17,methyltransferase like 17,mitochondrion|ribosome|ribonucleoprotein complex|,translation|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|copper ion binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,2.14,10,-0.2,1.54,-0.2,3.45,-3.45,0.506,0,0,-1.2,0.3
ENSMUSG00000024883,RIN1,Ras and Rab interactor 1,cytoplasm|cytoskeleton|plasma membrane|membrane|dendrite|neuronal cell body|,endocytosis|signal transduction|memory|associative learning|negative regulation of synaptic plasticity|,GTPase activator activity|Ras GTPase binding|,10,0.3,0.607,10,0.5,3.32,0.5,3.44,3.44,0.507,0,0,-0.3,1.6
ENSMUSG00000060807,SERPINA6,"serine (or cysteine) peptidase inhibitor, clade A, member 6",extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|,transport|glucocorticoid metabolic process|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|steroid binding|steroid binding|steroid binding|lipid binding|,10,0.5,4.45,10,0.1,0.555,0.3,3.43,3.43,0.508,0,0,-0.3,1.3
ENSMUSG00000044086,LMOD3,leiomodin 3 (fetal),cellular_component|,biological_process|,molecular_function|,9,0,0,9,0.4,4.44,0.3,3.43,3.43,0.508,0,0,-0.4,1.5
ENSMUSG00000042298,TTC19,tetratricopeptide repeat domain 19,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,mitochondrial respiratory chain complex III assembly|,protein binding|,10,-0.2,1.49,10,-0.2,2.14,-0.2,3.4,-3.4,0.51,0,0,-1.2,0.5
ENSMUSG00000021361,TMEM14C,transmembrane protein 14C,mitochondrion|membrane|integral component of membrane|,heme biosynthetic process|biological_process|,molecular_function|,9,0,0,9,0.6,4.75,0.5,3.37,3.37,0.512,0,0,-0.7,1.6
ENSMUSG00000027599,ARMC1,armadillo repeat containing 1,mitochondrion|,biological_process|metal ion transport|,metal ion binding|,10,-0.2,0.845,10,0.4,5.08,0.3,3.32,3.32,0.516,0,0,-0.5,1.4
ENSMUSG00000024911,FIBP,fibroblast growth factor (acidic) intracellular binding protein,nucleus|membrane|extracellular vesicular exosome|,biological_process|,fibroblast growth factor binding|,10,0.1,0.12,10,0.2,3.87,0.2,3.31,3.31,0.516,0,0,-0.5,1.2
ENSMUSG00000032413,RASA2,RAS p21 protein activator 2,intracellular|cytoplasm|plasma membrane|membrane|intrinsic component of the cytoplasmic side of the plasma membrane|,signal transduction|positive regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|intracellular signal transduction|negative regulation of Ras protein signal transduction|regulation of small GTPase mediated signal transduction|,GTPase activator activity|Ras GTPase activator activity|Ras GTPase activator activity|metal ion binding|,10,0.2,0.392,10,0.4,3.33,0.3,3.31,3.31,0.516,0,0,-0.3,1.4
ENSMUSG00000028760,EIF4G3,"eukaryotic translation initiation factor 4 gamma, 3",cellular_component|,positive regulation of protein phosphorylation|translation|translational initiation|regulation of translation|spermatogenesis|positive regulation of translation|positive regulation of meiosis I|,RNA binding|translation initiation factor activity|protein binding|poly(A) RNA binding|,10,0.1,0.17,10,0.4,3.87,0.3,3.3,3.3,0.517,0,0,-0.2,1.4
ENSMUSG00000052273,DNAH3,"dynein, axonemal, heavy chain 3",cellular_component|cytoplasm|cytoskeleton|microtubule|cilium|dynein complex|cell projection|,microtubule-based movement|biological_process|,nucleotide binding|molecular_function|motor activity|microtubule motor activity|ATP binding|,10,-0.2,1.09,10,0.6,3.54,0.6,3.23,3.23,0.523,0,0,-0.4,1.7
ENSMUSG00000026950,NEB,nebulin,striated muscle thin filament|myofibril|Z disc|Z disc|protein complex|contractile fiber|extracellular vesicular exosome|,regulation of actin filament length|sarcomere organization|,None,10,-0.3,1.44,10,-0.4,2.11,-0.4,3.22,-3.22,0.524,0,0,-1.4,0.4
ENSMUSG00000074639,BC089597,cDNA sequence BC089597,cellular_component|,biological_process|,molecular_function|,10,0.9,2.79,10,-0.8,3.02,-0.7,3.19,-3.19,0.526,0,0,-1.8,1.4
ENSMUSG00000036992,NXT1,NTF2-related export protein 1,intracellular|nucleus|nuclear pore|cytoplasm|,RNA export from nucleus|protein export from nucleus|transport|protein transport|mRNA transport|,protein binding|Ran GTPase binding|,10,-0.1,0.256,10,0.5,5.15,0.5,3.19,3.19,0.526,0,0,-0.3,1.7
ENSMUSG00000046338,GPAT2,"glycerol-3-phosphate acyltransferase 2, mitochondrial",mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,glycerol-3-phosphate metabolic process|lipid metabolic process|metabolic process|phospholipid biosynthetic process|triglyceride biosynthetic process|cellular lipid metabolic process|,"glycerol-3-phosphate O-acyltransferase activity|O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.2,1.37,10,0.3,4.47,0.3,3.18,3.18,0.527,0,0,-0.8,1.3
ENSMUSG00000057134,ADO,2-aminoethanethiol (cysteamine) dioxygenase,mitochondrion|,oxidation-reduction process|,protein binding|oxidoreductase activity|metal ion binding|cysteamine dioxygenase activity|dioxygenase activity|,10,0.3,0.25,10,0.2,3.19,0.3,3.18,3.18,0.527,0,0,-0.4,1.3
ENSMUSG00000042354,GNL3,guanine nucleotide binding protein-like 3 (nucleolar),extracellular space|nucleus|nucleoplasm|nucleolus|nucleolus|membrane|,GTP catabolic process|cell proliferation|regulation of cell proliferation|ribosome biogenesis|,nucleotide binding|GTPase activity|protein binding|GTP binding|GTP binding|poly(A) RNA binding|,8,0.4,2.68,8,-0.3,1.4,0.4,3.17,3.17,0.527,0,0,-0.6,1.8
ENSMUSG00000024132,ECI1,enoyl-Coenzyme A delta isomerase 1,mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|metabolic process|,catalytic activity|dodecenoyl-CoA delta-isomerase activity|dodecenoyl-CoA delta-isomerase activity|isomerase activity|identical protein binding|,10,-0.3,2.96,10,-0.3,0.36,-0.3,3.15,-3.15,0.529,0,0,-1.3,0.4
ENSMUSG00000019054,FIS1,fission 1 (mitochondrial outer membrane) homolog (yeast),mitochondrion|mitochondrion|mitochondrial outer membrane|peroxisome|peroxisome|integral component of peroxisomal membrane|endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|protein complex|,mitochondrial fission|mitochondrial fission|mitochondrion degradation|release of cytochrome c from mitochondria|protein targeting to mitochondrion|apoptotic process|positive regulation of cytosolic calcium ion concentration|mitochondrial fusion|regulation of mitochondrion organization|peroxisome fission|peroxisome fission|negative regulation of endoplasmic reticulum calcium ion concentration|calcium-mediated signaling using intracellular calcium source|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|mitochondrial fragmentation involved in apoptotic process|protein homooligomerization|positive regulation of mitochondrial calcium ion concentration|mitochondrion morphogenesis|positive regulation of mitochondrial fission|positive regulation of protein targeting to membrane|positive regulation of intrinsic apoptotic signaling pathway|,receptor binding|,10,-0.3,1.67,10,-0.2,1.82,-0.2,3.15,-3.15,0.529,0,0,-1.3,0.5
ENSMUSG00000018999,SLC35B4,"solute carrier family 35, member B4",Golgi apparatus|membrane|integral component of membrane|,regulation of gluconeogenesis|transport|carbohydrate transport|UDP-N-acetylglucosamine transport|UDP-xylose transport|ion transmembrane transport|transmembrane transport|pyrimidine nucleotide-sugar transmembrane transport|,UDP-N-acetylglucosamine transmembrane transporter activity|UDP-xylose transmembrane transporter activity|,10,0.2,1.46,10,0.3,2.05,0.3,3.15,3.15,0.529,0,0,-0.5,1.3
ENSMUSG00000002059,RAB34,"RAB34, member RAS oncogene family",ruffle|intracellular|cell|cytoplasm|early endosome|Golgi apparatus|Golgi stack|membrane|cytoplasmic vesicle|vesicle|Golgi cisterna|phagocytic vesicle|perinuclear region of cytoplasm|extracellular vesicular exosome|,GTP catabolic process|transport|endocytosis|small GTPase mediated signal transduction|protein transport|antigen processing and presentation|lysosome localization|Golgi to plasma membrane protein transport|Golgi to plasma membrane protein transport|protein localization to plasma membrane|phagosome maturation|phagosome-lysosome fusion|,nucleotide binding|GTPase activity|protein binding|GTP binding|guanyl nucleotide binding|,10,0,0,10,0.4,4.58,0.3,3.12,3.12,0.532,0,0,-0.6,1.4
ENSMUSG00000039632,CCDC151,coiled-coil domain containing 151,cellular_component|,biological_process|,molecular_function|,10,0.8,0.992,10,0.8,2.33,0.8,3.11,3.11,0.532,0,0,-0.2,1.9
ENSMUSG00000021373,CAP2,"CAP, adenylate cyclase-associated protein, 2 (yeast)",plasma membrane|membrane|,cell morphogenesis|cytoskeleton organization|,actin binding|,10,0.6,2.5,10,0.3,1.51,0.4,3.1,3.1,0.533,0,0,-0.2,1.6
ENSMUSG00000079508,APOO,apolipoprotein O,mitochondrion|,biological_process|,molecular_function|,10,-0.1,0.0899,10,-0.3,3.36,-0.3,3.1,-3.1,0.533,0,0,-1.5,0.5
ENSMUSG00000029499,PXMP2,peroxisomal membrane protein 2,cytoplasm|mitochondrion|peroxisome|peroxisomal membrane|membrane|membrane|integral component of membrane|protein complex|,None,None,10,0.1,0.708,10,0.2,2.62,0.2,3.1,3.1,0.533,0,0,-1,1.2
ENSMUSG00000030824,NUCB1,nucleobindin 1,extracellular space|cytoplasm|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|membrane|extracellular vesicular exosome|,None,DNA binding|calcium ion binding|metal ion binding|,10,-0.5,3.88,10,0.2,2.02,-0.3,3.1,-3.1,0.533,0,0,-1.5,0.6
ENSMUSG00000020848,DOC2B,"double C2, beta",cell|cytoplasm|plasma membrane|plasma membrane|synaptic vesicle|membrane|SNARE complex|,transport|protein localization|positive regulation of vesicle fusion|positive regulation of insulin secretion|positive regulation of calcium ion-dependent exocytosis|calcium ion-dependent exocytosis of neurotransmitter|calcium ion-dependent exocytosis of neurotransmitter|,transporter activity|protein binding|calcium-dependent phospholipid binding|syntaxin binding|,10,-0.2,0.568,10,0.8,5.53,0.3,3.05,3.05,0.537,0,0,-0.3,1.9
ENSMUSG00000019831,WASF1,"WAS protein family, member 1",cytoplasm|mitochondrion|mitochondrial outer membrane|cytoskeleton|lamellipodium|cell junction|SCAR complex|synapse|,Rac protein signal transduction|actin cytoskeleton organization|lamellipodium morphogenesis|positive regulation of Arp2/3 complex-mediated actin nucleation|,actin binding|protein binding|protein complex binding|Rac GTPase binding|,10,-0.3,3.06,10,-0.1,0.759,-0.2,3.05,-3.05,0.537,0,0,-1.3,0.5
ENSMUSG00000030616,SYTL2,synaptotagmin-like 2,nucleus|cytoplasm|Golgi apparatus|plasma membrane|plasma membrane|membrane|extrinsic component of plasma membrane|melanosome|exocytic vesicle|,intracellular protein transport|exocytosis|exocytosis|vesicle docking involved in exocytosis|negative regulation of phosphatase activity|positive regulation of mucus secretion|,"phosphatidylserine binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|Rab GTPase binding|phosphatase binding|neurexin family protein binding|",10,-0.3,1.75,10,-0.4,1.66,-0.3,3.05,-3.05,0.537,0,0,-1.4,0.7
ENSMUSG00000026469,XPR1,xenotropic and polytropic retrovirus receptor 1,plasma membrane|membrane|integral component of membrane|,response to virus|response to virus|,virus receptor activity|receptor activity|,10,-0.5,2.7,10,-0.6,0.764,-0.5,3.05,-3.05,0.537,0,0,-1.7,0.4
ENSMUSG00000032739,PRAM1,PML-RAR alpha-regulated adaptor molecule 1,cellular_component|,integrin-mediated signaling pathway|regulation of neutrophil degranulation|,molecular_function|lipid binding|,10,-0.1,0.237,10,0.4,4.95,0.3,3.04,3.04,0.538,0,0,-0.5,1.5
ENSMUSG00000022999,LMBR1L,limb region 1 like,cellular_component|plasma membrane|membrane|integral component of membrane|,endocytosis|biological_process|,molecular_function|,10,0.1,0.196,10,0.2,3.09,0.2,3.02,3.02,0.54,0,0,-0.5,1.3
ENSMUSG00000034706,DNAIC2,"dynein, axonemal, intermediate chain 2",cytoplasm|cytoskeleton|axonemal dynein complex|microtubule|cilium|axoneme|dynein complex|cell projection|,metabolic process|cell projection organization|cilium assembly|,motor activity|microtubule motor activity|protein binding|,9,0.4,0.835,9,0.2,2.46,0.2,3.01,3.01,0.541,0,0,-0.3,1.6
ENSMUSG00000038352,ARL5C,ADP-ribosylation factor-like 5C,cellular_component|intracellular|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0,0,10,-0.2,3.5,-0.2,3.01,-3.01,0.541,0,0,-1.3,0.6
ENSMUSG00000039577,NPHP4,nephronophthisis 4 (juvenile) homolog (human),cytoplasm|centrosome|cytoskeleton|cell-cell junction|tight junction|cilium|cell junction|photoreceptor connecting cilium|cell projection|ribbon synapse|,sperm motility|photoreceptor cell outer segment organization|photoreceptor cell maintenance|retina development in camera-type eye|,protein binding|,10,-0.2,2.77,10,-0.1,0.709,-0.2,3,-3,0.542,0,0,-1.3,0.5
ENSMUSG00000036278,MACROD1,MACRO domain containing 1,nucleus|mitochondrion|,cellular response to DNA damage stimulus|purine nucleoside metabolic process|protein de-ADP-ribosylation|,"purine-specific mismatch base pair DNA N-glycosylase activity|histone deacetylase activity|uracil DNA N-glycosylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|single-strand selective uracil DNA N-glycosylase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|DNA N-glycosylase activity|deacetylase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|DNA-3-methylbase glycosylase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0.3,2.8,10,0.2,0.54,0.3,2.98,2.98,0.543,0,0,-0.3,1.5
ENSMUSG00000024451,ARAP3,"ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3",ruffle|intracellular|cytoplasm|cytoskeleton|plasma membrane|membrane|lamellipodium|cell projection|,signal transduction|regulation of cell shape|negative regulation of cell migration|regulation of ARF GTPase activity|positive regulation of Rho GTPase activity|negative regulation of Rac protein signal transduction|negative regulation of Rho protein signal transduction|,"GTPase activator activity|Rho GTPase activator activity|protein binding|phosphatidylinositol-3,4,5-trisphosphate binding|ARF GTPase activator activity|zinc ion binding|phosphatidylinositol-3,4-bisphosphate binding|metal ion binding|",10,-0.4,4.23,10,-0.1,0.262,-0.3,2.94,-2.94,0.547,0,0,-1.4,0.5
ENSMUSG00000037826,PPM1K,protein phosphatase 1K (PP2C domain containing),mitochondrion|mitochondrion|,protein dephosphorylation|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,1,4.97,10,0.2,0.575,0.3,2.93,2.93,0.547,0,0,-0.1,2
ENSMUSG00000035811,UGT2B35,"UDP glucuronosyltransferase 2 family, polypeptide B35",intracellular membrane-bounded organelle|extracellular vesicular exosome|,None,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-1.4,6.23,10,0.2,1.89,-1.4,2.93,-2.93,0.547,0,0,-2,0.4
ENSMUSG00000020780,SRP68,signal recognition particle 68,"nucleus|nucleolus|cytoplasm|signal recognition particle, endoplasmic reticulum targeting|ribonucleoprotein complex|",SRP-dependent cotranslational protein targeting to membrane|response to drug|,RNA binding|signal recognition particle binding|7S RNA binding|endoplasmic reticulum signal peptide binding|poly(A) RNA binding|,9,-0.3,1.86,10,-0.2,1.56,-0.3,2.91,-2.91,0.549,0,0,-1.4,0.8
ENSMUSG00000069072,SLC7A14,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 14",membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|negative regulation of phosphatase activity|,molecular_function|amino acid transmembrane transporter activity|,10,0.8,0.625,10,-0.3,3.4,-0.3,2.9,-2.9,0.55,0,0,-1.2,1.5
ENSMUSG00000078954,ARHGAP8,Rho GTPase activating protein 8,intracellular|,signal transduction|positive regulation of Rho GTPase activity|,GTPase activator activity|Rho GTPase activator activity|,10,-0.3,3.4,10,-0.1,0.0573,-0.3,2.89,-2.89,0.551,0,0,-1.3,0.9
ENSMUSG00000003429,RPS11,ribosomal protein S11,intracellular|ribosome|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,osteoblast differentiation|translation|,RNA binding|structural constituent of ribosome|rRNA binding|poly(A) RNA binding|,7,0.6,0.193,6,0.7,2.9,0.7,2.86,2.86,0.554,0,0,-0.2,2
ENSMUSG00000055553,KXD1,KxDL motif containing 1,BLOC-1 complex|,vesicle-mediated transport|,protein binding|,10,0.4,2.88,10,0.9,2.03,0.7,2.86,2.86,0.554,0,0,-0.3,1.8
ENSMUSG00000031176,DYNLT3,dynein light chain Tctex-type 3,"chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|cytoskeleton|cytoplasmic dynein complex|microtubule|dynein complex|",transport|cell cycle|mitotic nuclear division|regulation of mitotic cell cycle|cell division|,motor activity|identical protein binding|,10,0.5,4.16,10,0.1,0.101,0.4,2.81,2.81,0.558,0,0,-0.4,2
ENSMUSG00000040124,GORAB,"golgin, RAB6-interacting",nucleus|cytoplasm|cytoplasm|Golgi apparatus|,biological_process|,protein binding|,10,0.7,4.27,10,0.1,0.839,0.2,2.8,2.8,0.559,0,0,-0.1,1.7
ENSMUSG00000037979,CCDC92,coiled-coil domain containing 92,cytoplasm|centriole|cytoskeleton|,biological_process|,molecular_function|,10,0.1,0.239,10,0.4,3.75,0.3,2.79,2.79,0.56,0,0,-0.3,1.5
ENSMUSG00000037287,TBCEL,tubulin folding cofactor E-like,cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,-0.2,1.19,10,0.3,3.25,0.3,2.77,2.77,0.561,0,0,-0.9,1.4
ENSMUSG00000069041,SLC25A31,"solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|cilium|membrane|integral component of membrane|cell projection|,transport|transmembrane transport|,transporter activity|,10,0.1,0.512,10,0.3,3.02,0.3,2.76,2.76,0.562,0,0,-0.4,1.5
ENSMUSG00000064138,FAM172A,"family with sequence similarity 172, member A",extracellular region|endoplasmic reticulum|,None,None,10,0.2,2.01,10,-0.3,2.05,0.2,2.75,2.75,0.563,0,0,-0.9,1.2
ENSMUSG00000005881,ERGIC3,ERGIC and golgi 3,endoplasmic reticulum|Golgi apparatus|membrane|membrane|integral component of membrane|,transport|biological_process|vesicle-mediated transport|,molecular_function|,10,0.9,1.82,10,0.3,2.4,0.2,2.74,2.74,0.564,0,0,-0.6,1.9
ENSMUSG00000055044,PDLIM1,PDZ and LIM domain 1 (elfin),transcription factor complex|cytoplasm|cytoskeleton|,"regulation of transcription, DNA-templated|",transcription coactivator activity|protein binding|zinc ion binding|metal ion binding|,10,-0.4,2.98,10,0.1,0.898,-0.3,2.73,-2.73,0.565,0,0,-1.5,0.5
ENSMUSG00000039783,KMO,kynurenine 3-monooxygenase (kynurenine 3-hydroxylase),mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|integral component of membrane|extracellular vesicular exosome|,tryptophan catabolic process|metabolic process|response to salt stress|pyridine nucleotide biosynthetic process|tryptophan catabolic process to kynurenine|NAD metabolic process|quinolinate biosynthetic process|oxidation-reduction process|kynurenine metabolic process|,monooxygenase activity|kynurenine 3-monooxygenase activity|NAD(P)H oxidase activity|oxidoreductase activity|flavin adenine dinucleotide binding|,10,-0.1,0.0251,10,0.3,3.83,0.2,2.71,2.71,0.566,0,0,-0.5,1.4
ENSMUSG00000044912,SYT16,synaptotagmin XVI,integral component of membrane|,exocytosis|biological_process|,protein binding|phospholipid binding|protein homodimerization activity|protein heterodimerization activity|,10,-0.1,0.198,10,0.5,4.19,0.5,2.71,2.71,0.566,0,0,-0.3,1.7
ENSMUSG00000024292,CYP4F14,"cytochrome P450, family 4, subfamily f, polypeptide 14",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,icosanoid metabolic process|arachidonic acid metabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|arachidonic acid monooxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|leukotriene-B4 20-monooxygenase activity|arachidonic acid binding|tocopherol omega-hydroxylase activity|alpha-tocopherol omega-hydroxylase activity|",10,-0.7,2.25,10,-0.5,0.788,-0.5,2.67,-2.67,0.57,0,0,-1.8,0.6
ENSMUSG00000022938,FAM3B,"family with sequence similarity 3, member B",extracellular region|extracellular space|cell|nuclear envelope lumen|extracellular vesicular exosome|,apoptotic process|insulin secretion|insulin secretion|,cytokine activity|,10,0,0,10,0.2,3.65,0.2,2.67,2.67,0.57,0,0,-0.5,1.4
ENSMUSG00000029151,SLC30A3,"solute carrier family 30 (zinc transporter), member 3",cytoplasm|late endosome|membrane|integral component of membrane|cell junction|synaptic vesicle membrane|cytoplasmic vesicle|neuron projection|synapse|,transport|ion transport|cation transport|zinc ion transport|detoxification of zinc ion|sequestering of zinc ion|positive regulation of transport|transmembrane transport|regulation of sequestering of zinc ion|regulation of sequestering of zinc ion|,cation transmembrane transporter activity|,10,-0.2,0.767,10,-0.3,2.21,-0.3,2.63,-2.63,0.573,0,0,-1.5,0.5
ENSMUSG00000032342,MTO1,mitochondrial translation optimization 1 homolog (S. cerevisiae),mitochondrion|mitochondrion|mitochondrion|,tRNA wobble uridine modification|tRNA processing|oxidation-reduction process|mitochondrial tRNA wobble uridine modification|,poly(A) RNA binding|flavin adenine dinucleotide binding|,9,-0.1,0.707,9,-1,4.48,-0.2,2.61,-2.61,0.575,0,0,-2,0.1
ENSMUSG00000037938,CHCHD5,coiled-coil-helix-coiled-coil-helix domain containing 5,cellular_component|mitochondrion|,biological_process|,molecular_function|,10,-0.3,3.6,10,0.8,1.52,-0.2,2.61,-2.61,0.575,0,0,-1,1.8
ENSMUSG00000023094,MSRB2,methionine sulfoxide reductase B2,mitochondrion|,response to oxidative stress|actin filament polymerization|protein repair|oxidation-reduction process|,"actin binding|peptide-methionine (S)-S-oxide reductase activity|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor|peptide-methionine (R)-S-oxide reductase activity|metal ion binding|methionine-R-sulfoxide reductase activity|",10,0.7,5.38,10,0,0,0.5,2.58,2.58,0.578,0,0,-0.1,1.8
ENSMUSG00000020695,MRC2,"mannose receptor, C type 2",cell surface|membrane|integral component of membrane|,osteoblast differentiation|endocytosis|collagen catabolic process|,collagen binding|collagen binding|carbohydrate binding|,10,0.1,0.248,10,0.2,2.66,0.2,2.57,2.57,0.579,0,0,-0.6,1.4
ENSMUSG00000027522,STX16,syntaxin 16,nucleolus|Golgi apparatus|membrane|integral component of membrane|SNARE complex|intracellular membrane-bounded organelle|,"transport|intracellular protein transport|intra-Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|retrograde transport, endosome to Golgi|",SNAP receptor activity|protein binding|,10,-0.1,0.0852,10,-0.3,3.34,-0.3,2.56,-2.56,0.58,0,0,-1.4,0.5
ENSMUSG00000035615,FRMPD1,FERM and PDZ domain containing 1,cytoplasm|cytoskeleton|plasma membrane|membrane|extracellular vesicular exosome|,signal transduction|biological_process|,molecular_function|,10,-0.2,0.663,10,-0.2,2.07,-0.2,2.55,-2.55,0.581,0,0,-1.6,0.8
ENSMUSG00000032841,PRR5L,proline rich 5 like,intracellular|mitochondrion|TORC2 complex|,negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|negative regulation of signal transduction|regulation of fibroblast migration|regulation of fibroblast migration|positive regulation of phosphatidylinositol 3-kinase signaling|TORC2 signaling|TORC2 signaling|,ubiquitin protein ligase binding|,10,0.2,1.48,10,0.2,1.24,0.2,2.53,2.53,0.583,0,0,-0.8,1.4
ENSMUSG00000001053,N4BP3,NEDD4 binding protein 3,membrane|cytoplasmic vesicle|,biological_process|,protein binding|,10,-0.5,4.91,10,0.1,0.125,-0.4,2.52,-2.52,0.584,0,0,-1.7,0.4
ENSMUSG00000020038,CRY1,cryptochrome 1 (photolyase-like),nucleus|nucleolus|cytoplasm|mitochondrion|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|gluconeogenesis|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|DNA damage induced protein phosphorylation|circadian rhythm|circadian rhythm|protein-chromophore linkage|lipid storage|response to insulin|circadian regulation of gene expression|circadian regulation of gene expression|response to glucagon|glucose homeostasis|regulation of circadian rhythm|negative regulation of circadian rhythm|negative regulation of circadian rhythm|entrainment of circadian clock by photoperiod|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|rhythmic process|response to stimulus|regulation of DNA damage checkpoint|negative regulation of glucocorticoid receptor signaling pathway|negative regulation of glucocorticoid receptor signaling pathway|negative regulation of glucocorticoid secretion|",nucleotide binding|transcription factor binding transcription factor activity|core promoter sequence-specific DNA binding|core promoter binding|double-stranded DNA binding|double-stranded DNA binding|DNA photolyase activity|protein binding|transcription factor binding|photoreceptor activity|kinase binding|protein kinase binding|phosphatase binding|nuclear hormone receptor binding|nuclear hormone receptor binding|histone deacetylase binding|,10,-0.8,1.13,10,0.2,2.02,0.2,2.51,2.51,0.585,0,0,-1.8,0.9
ENSMUSG00000045854,LYRM2,LYR motif containing 2,mitochondrion|,biological_process|,molecular_function|,9,-0.2,0.738,9,0.4,3.12,0.4,2.48,2.48,0.587,0,0,-1.3,1.6
ENSMUSG00000030050,GKN1,gastrokine 1,extracellular region|secretory granule|,positive regulation of cell proliferation|positive regulation of cell division|,growth factor activity|,10,0.1,0.00257,10,0.2,2.81,0.2,2.46,2.46,0.589,0,0,-0.8,1.4
ENSMUSG00000034126,POMT2,protein-O-mannosyltransferase 2,endoplasmic reticulum|membrane|integral component of membrane|,protein O-linked glycosylation|,"mannosyltransferase activity|dolichyl-phosphate-mannose-protein mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0.2,1.38,10,0.2,1.24,0.2,2.43,2.43,0.592,0,0,-0.4,1.6
ENSMUSG00000056078,LIPM,"lipase, family member M",cellular_component|extracellular region|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|hydrolase activity, acting on ester bonds|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.4,1.44,10,0.3,4.41,0.3,2.4,2.4,0.595,0,0,-1.3,1.3
ENSMUSG00000037351,ACTR1B,"ARP1 actin-related protein 1B, centractin beta",cytoplasm|centrosome|cytoskeleton|membrane|extracellular vesicular exosome|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0.3,2.81,0.3,2.38,2.38,0.597,0,0,-0.4,1.6
ENSMUSG00000004748,MTFP1,mitochondrial fission process 1,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,mitochondrial fission|apoptotic process|mitochondrial membrane organization|,molecular_function|,10,0.1,0.439,10,0.3,2.35,0.3,2.38,2.38,0.597,0,0,-0.3,1.5
ENSMUSG00000025577,CBX2,chromobox 2,euchromatin|heterochromatin|nucleus|nucleus|PcG protein complex|PcG protein complex|PRC1 complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|development of primary sexual characteristics|",DNA binding|chromatin binding|protein binding|methylated histone binding|,10,0.1,0.499,10,-0.4,4.87,-0.3,2.38,-2.38,0.597,0,0,-1.5,0.7
ENSMUSG00000021731,MRPS30,mitochondrial ribosomal protein S30,cellular_component|mitochondrion|ribosome|ribonucleoprotein complex|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,10,1.4,4.59,10,0.3,3.15,1.4,2.36,2.36,0.599,0,0,-0.7,2
ENSMUSG00000021696,ELOVL7,"ELOVL family member 7, elongation of long chain fatty acids (yeast)",endoplasmic reticulum|membrane|integral component of membrane|,"lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation, saturated fatty acid|fatty acid elongation, polyunsaturated fatty acid|very long-chain fatty acid biosynthetic process|",transferase activity|,10,0.3,0.624,10,0.2,2.01,0.2,2.36,2.36,0.599,0,0,-1.2,1.5
ENSMUSG00000033845,MRPL15,mitochondrial ribosomal protein L15,mitochondrion|mitochondrion|mitochondrial large ribosomal subunit|ribosome|large ribosomal subunit|ribonucleoprotein complex|,mitochondrial genome maintenance|translation|,structural constituent of ribosome|poly(A) RNA binding|,10,-0.7,1.35,10,-0.7,1.16,-0.7,2.34,-2.34,0.601,0,0,-1.9,1.1
ENSMUSG00000046756,MRPS7,mitchondrial ribosomal protein S7,mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,-0.1,0.293,10,-0.9,3.39,-0.2,2.33,-2.33,0.602,0,0,-2,0.6
ENSMUSG00000034156,BZRAP1,benzodiazepine receptor associated protein 1,cytoplasm|mitochondrion|,biological_process|,benzodiazepine receptor binding|,10,0.3,2.63,10,0.1,0.279,0.2,2.33,2.33,0.602,0,0,-0.5,1.5
ENSMUSG00000019312,GRB7,growth factor receptor bound protein 7,cytoplasm|cytosol|cytosol|plasma membrane|focal adhesion|cytoplasmic stress granule|membrane|cell junction|cell projection|,signal transduction|positive regulation of signal transduction|negative regulation of translation|positive regulation of cell migration|stress granule assembly|,RNA binding|SH3/SH2 adaptor activity|protein binding|lipid binding|protein kinase binding|phosphatidylinositol binding|identical protein binding|,10,0.1,0.0869,10,0.7,4.62,0.6,2.28,2.28,0.607,0,0,-0.2,1.9
ENSMUSG00000035505,COX18,cytochrome c oxidase assembly protein 18,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial inner membrane|,respiratory chain complex IV assembly|protein transport|protein insertion into mitochondrial membrane|protein insertion into membrane|,protein transporter activity|,10,0.1,0.587,9,0.3,2.04,0.2,2.28,2.28,0.607,0,0,-1,1.4
ENSMUSG00000021809,NUDT13,nudix (nucleoside diphosphate linked moiety X)-type motif 13,mitochondrion|,biological_process|,GPI-anchor transamidase activity|hydrolase activity|metal ion binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0.3,1.44,10,0.2,1.23,0.2,2.28,2.28,0.607,0,0,-0.4,1.7
ENSMUSG00000030309,CAPRIN2,caprin family member 2,nucleus|cytoplasm|mitochondrion|centrosome|receptor complex|,negative regulation of translation|cell differentiation|negative regulation of cell growth|positive regulation of protein binding|positive regulation of peptidyl-serine phosphorylation|regulation of growth|positive regulation of transcription from RNA polymerase II promoter|positive regulation of dendrite morphogenesis|positive regulation of dendritic spine morphogenesis|positive regulation of canonical Wnt signaling pathway|,RNA binding|receptor binding|,9,-0.2,0.573,9,0.6,2.92,0.5,2.26,2.26,0.608,0,0,-0.5,1.8
ENSMUSG00000021339,MRS2,MRS2 magnesium homeostasis factor homolog (S. cerevisiae),mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|magnesium ion transport|,molecular_function|magnesium ion transmembrane transporter activity|,10,0.2,0.796,10,0.2,1.62,0.2,2.25,2.25,0.609,0,0,-0.5,1.5
ENSMUSG00000044365,CXXC4,CXXC finger 4,cytoplasm|cytoplasm|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|,Wnt signaling pathway|negative regulation of Wnt signaling pathway|,DNA binding|zinc ion binding|PDZ domain binding|metal ion binding|,10,0.3,1.55,10,0.7,2.56,0.5,2.25,2.25,0.609,0,0,-0.4,1.8
ENSMUSG00000029032,ARHGEF16,Rho guanine nucleotide exchange factor (GEF) 16,cytoplasm|,activation of Rac GTPase activity|activation of Cdc42 GTPase activity|regulation of Rho protein signal transduction|cell chemotaxis|positive regulation of establishment of protein localization to plasma membrane|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho GTPase binding|PDZ domain binding|receptor tyrosine kinase binding|,10,-0.6,2.06,10,-0.2,1.38,-0.3,2.23,-2.23,0.611,0,0,-1.8,0.7
ENSMUSG00000086040,WIPF3,"WAS/WASL interacting protein family, member 3",cytoplasm|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,actin binding|SH3 domain binding|,10,0,0,10,0.2,3.11,0.2,2.23,2.23,0.611,0,0,-0.7,1.5
ENSMUSG00000005474,MYL10,"myosin, light chain 10, regulatory",mitochondrion|mitochondrion|,biological_process|,calcium ion binding|metal ion binding|,10,0,0,10,0.3,3.22,0.2,2.22,2.22,0.613,0,0,-1.4,1.2
ENSMUSG00000010021,KIF19A,kinesin family member 19A,cytoplasm|cytoskeleton|kinesin complex|microtubule|cilium|axoneme|cell projection|,microtubule-based movement|axonemal microtubule depolymerization|plus-end specific microtubule depolymerization|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|plus-end-directed microtubule motor activity|,10,0.2,1.07,10,0.2,1.32,0.2,2.21,2.21,0.614,0,0,-1.2,1.1
ENSMUSG00000061906,UGT2B38,"UDP glucuronosyltransferase 2 family, polypeptide B38",endoplasmic reticulum|,None,glucuronosyltransferase activity|transferase activity|,10,0,0,10,-0.2,3.47,-0.2,2.2,-2.2,0.615,0,0,-1.4,0.8
ENSMUSG00000022280,RNF19A,ring finger protein 19A,cytoplasm|cytoskeleton|membrane|integral component of membrane|,None,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.405,10,0.2,2.15,0.2,2.18,2.18,0.617,0,0,-0.6,1.5
ENSMUSG00000024163,MAPK8IP3,mitogen-activated protein kinase 8 interacting protein 3,Golgi membrane|cytoplasm|smooth endoplasmic reticulum|Golgi apparatus|plasma membrane|dendrite|axolemma|cytoplasmic vesicle|cell projection|neuron projection|,in utero embryonic development|JNK cascade|activation of JUN kinase activity|axon guidance|respiratory gaseous exchange|protein localization|post-embryonic development|positive regulation of signal transduction|regulation of gene expression|vesicle-mediated transport|phosphorylation|forebrain development|positive regulation of JUN kinase activity|positive regulation of neuron differentiation|regulation of JNK cascade|lung alveolus development|lung morphogenesis|,MAP-kinase scaffold activity|MAP-kinase scaffold activity|protein binding|JUN kinase binding|kinase activity|transferase activity|kinesin binding|mitogen-activated protein kinase kinase binding|mitogen-activated protein kinase kinase binding|mitogen-activated protein kinase kinase kinase binding|,10,0.2,1.64,10,0.4,0.833,0.3,2.18,2.18,0.617,0,0,-0.5,1.6
ENSMUSG00000039852,RERE,arginine glutamic acid dipeptide (RE) repeats,histone deacetylase complex|nucleus|,"chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0.1,0.186,10,0.2,2.31,0.2,2.17,2.17,0.618,0,0,-0.6,1.5
ENSMUSG00000073468,SFT2D1,SFT2 domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.3,1.62,10,0.7,1.94,0.6,2.15,2.15,0.62,0,0,-0.5,1.9
ENSMUSG00000043079,SYNPO,synaptopodin,stress fiber|cytoplasm|cytoskeleton|plasma membrane|tight junction|actin cytoskeleton|actin cytoskeleton|membrane|cell junction|dendrite|cell projection|dendritic spine|synapse|postsynaptic membrane|,cortical cytoskeleton organization|positive regulation of actin filament bundle assembly|regulation of stress fiber assembly|,actin binding|,10,-0.3,2.58,10,-0.1,0.233,-0.2,2.14,-2.14,0.621,0,0,-1.5,0.7
ENSMUSG00000024524,GNAL,"guanine nucleotide binding protein, alpha stimulating, olfactory type",heterotrimeric G-protein complex|heterotrimeric G-protein complex|,response to amphetamine|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|adenylate cyclase-activating dopamine receptor signaling pathway|sensory perception of smell|response to caffeine|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|signal transducer activity|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|metal ion binding|toxin receptor binding|,10,0,0,10,0.9,4.77,0.9,2.14,2.14,0.621,0,0,-0.1,2
ENSMUSG00000028057,RIT1,Ras-like without CAAX 1,intracellular|plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|Ras protein signal transduction|,nucleotide binding|protein binding|GTP binding|,10,-0.2,0.537,10,-0.2,1.76,-0.2,2.14,-2.14,0.621,0,0,-1.6,0.7
ENSMUSG00000037202,PRF1,perforin 1 (pore forming protein),extracellular region|extracellular space|endosome|plasma membrane|membrane|membrane|integral component of membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|cytolytic granule|,defense response to tumor cell|immune response to tumor cell|apoptotic process|circadian rhythm|cytolysis|cytolysis|protein homooligomerization|protein homooligomerization|defense response to virus|transmembrane transport|transmembrane transport|,calcium ion binding|wide pore channel activity|wide pore channel activity|metal ion binding|,10,0.2,0.909,10,0.2,1.38,0.2,2.13,2.13,0.622,0,0,-0.4,1.6
ENSMUSG00000073988,TTPA,tocopherol (alpha) transfer protein,intracellular|cell|cytoplasm|late endosome|cytosol|,placenta development|embryonic placenta development|transport|response to pH|response to toxic substance|vitamin E metabolic process|vitamin E metabolic process|intermembrane transport|vitamin transport|intracellular pH reduction|negative regulation of cell death|negative regulation of establishment of blood-brain barrier|,"transporter activity|phosphatidylinositol-4,5-bisphosphate binding|lipid binding|vitamin E binding|vitamin E binding|vitamin E binding|vitamin binding|phosphatidylinositol-3,4-bisphosphate binding|",10,0.4,2.36,10,0.2,0.194,0.3,2.1,2.1,0.625,0,0,-0.6,1.5
ENSMUSG00000027534,SNX16,sorting nexin 16,cytoplasm|lysosome|endosome|early endosome|late endosome|membrane|extrinsic component of endosome membrane|,protein targeting to lysosome|transport|endosome to lysosome transport|protein transport|early endosome to late endosome transport|,lipid binding|phosphatidylinositol binding|identical protein binding|,10,-0.8,0.695,10,0.4,3.31,0.3,2.07,2.07,0.628,0,0,-1.6,1.4
ENSMUSG00000040852,PLEKHH2,"pleckstrin homology domain containing, family H (with MyTH4 domain) member 2",cytoplasm|cytoskeleton|plasma membrane|membrane|lamellipodium|cortical actin cytoskeleton|cell projection|,negative regulation of actin filament depolymerization|,actin binding|protein binding|identical protein binding|,10,0.9,2.6,10,0.3,0.888,0.4,2.07,2.07,0.628,0,0,-0.5,1.9
ENSMUSG00000001156,MXD1,MAX dimerization protein 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|protein binding|protein dimerization activity|,10,0.2,1.12,10,0.1,1.15,0.2,2.07,2.07,0.628,0,0,-0.6,1.6
ENSMUSG00000024869,NUDT8,nudix (nucleoside diphosphate linked moiety X)-type motif 8,mitochondrion|,biological_process|,"thiamine-pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|",10,-0.2,1.45,10,-0.2,0.744,-0.2,2.04,-2.04,0.631,0,0,-1.5,0.7
ENSMUSG00000034401,SPATA6,spermatogenesis associated 6,cellular_component|extracellular region|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,0.2,0.597,10,0.2,1.58,0.2,2.03,2.03,0.632,0,0,-0.7,1.5
ENSMUSG00000060176,KIF27,kinesin family member 27,cytoplasm|cytoskeleton|kinesin complex|microtubule|cilium|cell projection|extracellular vesicular exosome|,epithelial cilium movement|microtubule-based movement|ventricular system development|cell projection organization|cilium assembly|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|,10,0.2,1.93,10,0.1,0.375,0.2,2.03,2.03,0.632,0,0,-0.5,1.6
ENSMUSG00000019880,RSPO3,R-spondin 3 homolog (Xenopus laevis),extracellular region|,Wnt signaling pathway|response to stimulus|canonical Wnt signaling pathway|branching involved in labyrinthine layer morphogenesis|,receptor binding|receptor binding|frizzled binding|heparin binding|,10,0.1,0.267,10,-0.2,2.66,-0.1,2.02,-2.02,0.633,0,0,-1.3,1
ENSMUSG00000024068,SPAST,spastin,nucleus|nucleus|cytoplasm|endosome|endoplasmic reticulum|cytoskeleton|microtubule|microtubule cytoskeleton|microtubule cytoskeleton|membrane|integral component of membrane|midbody|cytoplasmic vesicle|extracellular vesicular exosome|,"microtubule bundle formation|ATP catabolic process|ER to Golgi vesicle-mediated transport|cell cycle|cytokinesis, completion of separation|multicellular organismal development|nervous system development|metabolic process|cell differentiation|protein hexamerization|microtubule severing|microtubule severing|microtubule severing|microtubule severing|protein homooligomerization|cell division|",nucleotide binding|catalytic activity|ATP binding|microtubule binding|microtubule-severing ATPase activity|hydrolase activity|alpha-tubulin binding|beta-tubulin binding|,10,-0.3,1.55,10,-0.9,2.94,-0.2,2.02,-2.02,0.633,0,0,-1.9,0.1
ENSMUSG00000098112,BIN2,bridging integrator 2,phagocytic cup|podosome|,"phagocytosis, engulfment|cell chemotaxis|podosome assembly|membrane tubulation|",phospholipid binding|,10,-0.1,0.169,10,-0.2,2.49,-0.2,2.01,-2.01,0.634,0,0,-1.3,1.2
ENSMUSG00000024697,GNA14,"guanine nucleotide binding protein, alpha 14",heterotrimeric G-protein complex|heterotrimeric G-protein complex|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|phospholipase C-activating dopamine receptor signaling pathway|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|signal transducer activity|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,0,0,10,0.4,3.84,0.4,2,2,0.635,0,0,-0.4,1.7
ENSMUSG00000041164,ZMIZ2,"zinc finger, MIZ-type containing 2",nucleus|mitochondrion|nuclear replication fork|,positive regulation of transcription from RNA polymerase II promoter|,zinc ion binding|ligand-dependent nuclear receptor transcription coactivator activity|metal ion binding|,10,-0.3,0.496,10,0.2,2.59,0.2,1.99,1.99,0.636,0,0,-1.2,1.3
ENSMUSG00000079657,RAB26,"RAB26, member RAS oncogene family",Golgi membrane|Golgi apparatus|membrane|secretory granule membrane|intrinsic component of plasma membrane|cytoplasmic vesicle|,transport|small GTPase mediated signal transduction|protein transport|regulation of exocytosis|exocrine system development|Golgi to plasma membrane protein transport|regulated secretory pathway|,nucleotide binding|protein binding|GTP binding|GMP binding|,10,0.2,0.53,10,0.2,1.6,0.2,1.98,1.98,0.637,0,0,-0.7,1.5
ENSMUSG00000032449,SLC25A36,"solute carrier family 25, member 36",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|response to estradiol|transmembrane transport|,molecular_function|,10,0,0,10,-0.3,3.74,-0.2,1.98,-1.98,0.637,0,0,-1.7,0.5
ENSMUSG00000038670,MYBPC2,"myosin binding protein C, fast-type",cytoskeleton|myosin filament|,muscle contraction|cell adhesion|,actin binding|structural constituent of cytoskeleton|,10,-0.2,0.343,10,-0.8,3.12,-0.2,1.97,-1.97,0.638,0,0,-1.8,1.1
ENSMUSG00000034473,SEC22A,SEC22 vesicle trafficking protein homolog A (S. cerevisiae),intracellular|cell|endoplasmic reticulum|membrane|integral component of membrane|,transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,None,10,-0.3,2,10,0.4,2.97,0.4,1.96,1.96,0.639,0,0,-0.7,1.7
ENSMUSG00000021928,EBPL,emopamil binding protein-like,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|sterol metabolic process|,molecular_function|cholestenol delta-isomerase activity|,10,1.6,0.857,10,-0.3,2.17,-0.2,1.96,-1.96,0.639,0,0,-1.9,2.3
ENSMUSG00000028082,SH3D19,SH3 domain protein D19,nucleus|cytoplasm|Golgi apparatus|plasma membrane|,cytoskeleton organization|regulation of cell morphogenesis|positive regulation of membrane protein ectodomain proteolysis|,protein binding|proline-rich region binding|,10,0.3,1.28,10,0.2,0.946,0.2,1.95,1.95,0.641,0,0,-0.5,1.6
ENSMUSG00000004665,CNN2,calponin 2,stress fiber|membrane|extracellular vesicular exosome|,positive regulation of gene expression|hemopoiesis|negative regulation of cell migration|actomyosin structure organization|regulation of actin filament-based process|wound healing|regulation of cell proliferation|negative regulation of phagocytosis|cellular response to mechanical stimulus|,actin binding|calmodulin binding|,9,-0.5,2.87,9,-0.1,0.253,-0.4,1.95,-1.95,0.641,0,0,-1.9,0.5
ENSMUSG00000039156,STIM2,stromal interaction molecule 2,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|cellular calcium ion homeostasis|activation of store-operated calcium channel activity|positive regulation of calcium ion transport|calcium ion transmembrane transport|,calcium channel regulator activity|calcium ion binding|protein binding|store-operated calcium channel activity|metal ion binding|,10,-0.3,1.48,10,0.3,2.76,0.2,1.95,1.95,0.641,0,0,-1.2,1.2
ENSMUSG00000021532,FASTKD3,FAST kinase domains 3,mitochondrion|mitochondrion|,cellular respiration|cellular respiration|,protein kinase activity|poly(A) RNA binding|,10,-0.2,1.96,10,-0.1,0.226,-0.2,1.92,-1.92,0.644,0,0,-1.7,0.5
ENSMUSG00000004961,SYT5,synaptotagmin V,endosome|synaptic vesicle|membrane|integral component of membrane|cell junction|dense core granule|cytoplasmic vesicle|neuron projection|neuronal cell body|synapse|perinuclear region of cytoplasm|,transport|calcium ion-dependent exocytosis|,transporter activity|calcium-dependent phospholipid binding|syntaxin binding|clathrin binding|metal ion binding|protein heterodimerization activity|,10,0.2,0.391,10,0.3,1.91,0.2,1.89,1.89,0.647,0,0,-1,1.4
ENSMUSG00000041957,PKP2,plakophilin 2,nucleus|intermediate filament|plasma membrane|cell-cell junction|adherens junction|adherens junction|intercalated disc|intercalated disc|cell junction|desmosome|,desmosome assembly|heart development|negative regulation of cell proliferation|gap junction assembly|single organismal cell-cell adhesion|negative regulation of cell migration|adherens junction maintenance|intermediate filament bundle assembly|maintenance of organ identity|ventricular cardiac muscle tissue morphogenesis|lipid homeostasis|cardiac muscle cell action potential|cardiac muscle cell action potential involved in contraction|ventricular cardiac muscle cell action potential|cell-cell signaling involved in cardiac conduction|bundle of His cell to Purkinje myocyte communication|regulation of heart rate by cardiac conduction|regulation of tight junction assembly|,protein kinase C binding|protein binding|intermediate filament binding|protein complex scaffold|,10,-0.3,1.82,10,0.2,2.83,0.2,1.88,1.88,0.648,0,0,-1.7,0.7
ENSMUSG00000017978,CADPS2,Ca2+-dependent activator protein for secretion 2,membrane|cytoplasmic membrane-bounded vesicle|cell junction|cytoplasmic vesicle|presynaptic membrane|synapse|postsynaptic membrane|,transport|exocytosis|cellular response to starvation|protein transport|synaptic vesicle priming|positive regulation of exocytosis|,protein binding|lipid binding|metal ion binding|,10,0,0,10,0.2,2.25,0.2,1.83,1.83,0.654,0,0,-0.7,1.6
ENSMUSG00000035836,UGT2B1,"UDP glucuronosyltransferase 2 family, polypeptide B1",intracellular membrane-bounded organelle|,cellular glucuronidation|biphenyl catabolic process|,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,10,-0.8,4.91,-0.8,1.82,-1.82,0.655,0,0,-2,1.3
ENSMUSG00000033658,DDX19B,DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b,nuclear envelope|membrane|extracellular vesicular exosome|,biological_process|,nucleotide binding|molecular_function|helicase activity|ATP binding|hydrolase activity|,10,0.4,3.9,10,0,0,0.2,1.81,1.81,0.656,0,0,-1.7,1.2
ENSMUSG00000049090,ZADH2,"zinc binding alcohol dehydrogenase, domain containing 2",mitochondrion|peroxisome|,oxidation-reduction process|,zinc ion binding|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.3,0.754,10,0.2,1.18,0.2,1.78,1.78,0.659,0,0,-0.7,1.6
ENSMUSG00000031711,ZFP330,zinc finger protein 330,"chromosome, centromeric region|nucleus|chromosome|nucleolus|midbody|",None,zinc ion binding|metal ion binding|,10,1.4,4.94,10,-0.6,0.651,1.4,1.78,1.78,0.659,0,0,-0.7,2
ENSMUSG00000037306,MAN1C1,"mannosidase, alpha, class 1C, member 1",Golgi apparatus|,mannose metabolic process|proteoglycan biosynthetic process|,"mannosyl-oligosaccharide 1,2-alpha-mannosidase activity|calcium ion binding|",10,0.3,2.19,10,0,0,0.3,1.75,1.75,0.663,0,0,-0.5,1.7
ENSMUSG00000063450,SYNE2,"spectrin repeat containing, nuclear envelope 2",nucleus|nuclear envelope|nuclear envelope|nuclear envelope|nuclear outer membrane|cytoplasm|mitochondrion|cytoskeleton|plasma membrane|focal adhesion|membrane|integral component of membrane|aggresome|sarcoplasmic reticulum|myofibril|Z disc|Z disc|lamellipodium membrane|filopodium membrane|nuclear membrane|nuclear membrane|nuclear lumen|SUN-KASH complex|intermediate filament cytoskeleton|,nuclear envelope organization|nuclear migration|establishment or maintenance of cell polarity|fibroblast migration|positive regulation of cell migration|nuclear migration along microfilament|protein localization to nucleus|centrosome localization|centrosome localization|cytoskeletal anchoring at nuclear membrane|,actin binding|,10,0.1,0.00079,10,-0.5,4.09,-0.3,1.74,-1.74,0.664,0,0,-1.8,0.7
ENSMUSG00000058022,ADTRP,androgen dependent TFPI regulating protein,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0729,10,0.6,2.63,0.5,1.71,1.71,0.667,0,0,-0.3,1.8
ENSMUSG00000021303,GNG4,"guanine nucleotide binding protein (G protein), gamma 4",heterotrimeric G-protein complex|plasma membrane|membrane|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|negative regulation of cell growth|,GTPase activity|signal transducer activity|,10,-0.1,0.0661,10,0.5,2.48,0.4,1.71,1.71,0.667,0,0,-0.5,1.8
ENSMUSG00000055923,AASDH,aminoadipate-semialdehyde dehydrogenase,cellular_component|,lipid metabolic process|fatty acid metabolic process|biological_process|metabolic process|oxidation-reduction process|,"nucleotide binding|molecular_function|catalytic activity|acyl-CoA ligase activity|L-aminoadipate-semialdehyde dehydrogenase activity|succinate-CoA ligase activity|ATP binding|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity|fatty acid ligase activity|oxidoreductase activity|ligase activity|3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity|benzoyl acetate-CoA ligase activity|2,4-dichlorobenzoate-CoA ligase activity|pivalate-CoA ligase activity|cyclopropanecarboxylate-CoA ligase activity|adipate-CoA ligase activity|citronellyl-CoA ligase activity|mentha-1,3-dione-CoA ligase activity|thiophene-2-carboxylate-CoA ligase activity|2,4,4-trimethylpentanoate-CoA ligase activity|cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity|3-hydroxypropionyl-CoA synthetase activity|perillic acid:CoA ligase (ADP-forming) activity|perillic acid:CoA ligase (AMP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity|pristanate-CoA ligase activity|malonyl-CoA synthetase activity|",10,0.1,0.144,10,0.2,1.86,0.2,1.71,1.71,0.667,0,0,-0.7,1.6
ENSMUSG00000011257,PABPC4,"poly(A) binding protein, cytoplasmic 4",nucleus|cytoplasm|cytoplasmic stress granule|ribonucleoprotein complex|,biological_process|,RNA binding|poly(A) binding|poly(U) RNA binding|poly(A) RNA binding|,10,0.4,0.548,10,0.2,1.49,0.2,1.7,1.7,0.668,0,0,-1,1.6
ENSMUSG00000024645,TIMM21,tranlocase of inner mitochondrial membrane 21,mitochondrion|mitochondrial inner membrane presequence translocase complex|membrane|integral component of membrane|,transport|protein transport|protein import into mitochondrial matrix|mitochondrial respiratory chain complex I assembly|mitochondrial respiratory chain complex IV assembly|,molecular_function|,10,0.3,0.773,10,0.5,1.42,0.3,1.7,1.7,0.668,0,0,-0.5,1.7
ENSMUSG00000022995,ENAH,enabled homolog (Drosophila),stress fiber|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|focal adhesion|actin cytoskeleton|lamellipodium|cell junction|filopodium|cell projection|synapse|,neural tube closure|cellular component movement|actin filament organization|multicellular organismal development|nervous system development|axon guidance|axon guidance|actin polymerization or depolymerization|actin cytoskeleton organization|cell differentiation|intracellular transport|,actin binding|protein binding|profilin binding|SH3 domain binding|WW domain binding|,10,0.2,0.259,10,-1,3.86,-0.3,1.69,-1.69,0.669,0,0,-2,0.3
ENSMUSG00000021704,MTX3,metaxin 3,cellular_component|,biological_process|,molecular_function|,10,0.3,0.826,10,0.8,2.41,0.2,1.69,1.69,0.669,0,0,-0.2,1.9
ENSMUSG00000027669,GNB4,"guanine nucleotide binding protein (G protein), beta 4",lysosomal membrane|heterotrimeric G-protein complex|cell body|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|,GTPase activity|signal transducer activity|protein complex binding|,10,-0.2,0.17,10,0.2,3.05,0.2,1.67,1.67,0.671,0,0,-1,1.5
ENSMUSG00000028240,CYP7A1,"cytochrome P450, family 7, subfamily a, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,lipid metabolic process|bile acid biosynthetic process|cholesterol catabolic process|cholesterol catabolic process|steroid metabolic process|cholesterol metabolic process|cholesterol homeostasis|oxidation-reduction process|regulation of bile acid biosynthetic process|positive regulation of bile acid biosynthetic process|cellular response to glucose stimulus|cellular response to cholesterol|,"monooxygenase activity|iron ion binding|cholesterol 7-alpha-monooxygenase activity|cholesterol 7-alpha-monooxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|",10,-0.5,2.07,10,-0.2,0.496,-0.3,1.66,-1.66,0.672,0,0,-1.8,0.4
ENSMUSG00000042759,APOBR,apolipoprotein B receptor,plasma membrane|membrane|membrane|very-low-density lipoprotein particle|low-density lipoprotein particle|chylomicron|,lipid metabolic process|triglyceride metabolic process|transport|lipid transport|receptor-mediated endocytosis|steroid metabolic process|cholesterol metabolic process|,lipoprotein particle receptor activity|very-low-density lipoprotein particle receptor activity|,10,0.1,0.226,10,0.1,1.55,0.1,1.66,1.66,0.672,0,0,-1,1.5
ENSMUSG00000090523,GYPC,glycophorin C,plasma membrane|membrane|membrane|integral component of membrane|cortical cytoskeleton|cortical cytoskeleton|,biological_process|,molecular_function|,10,-0.1,0.0952,10,-0.4,2.55,-0.2,1.65,-1.65,0.674,0,0,-1.7,0.9
ENSMUSG00000054889,DSP,desmoplakin,cornified envelope|nucleus|cytoplasm|mitochondrion|cytoskeleton|intermediate filament|plasma membrane|cell-cell junction|fascia adherens|intercalated disc|intercalated disc|membrane|basolateral plasma membrane|cell junction|desmosome|desmosome|extracellular vesicular exosome|,desmosome organization|ventricular compact myocardium morphogenesis|single organismal cell-cell adhesion|peptide cross-linking|keratinocyte differentiation|adherens junction organization|skin development|intermediate filament cytoskeleton organization|intermediate filament organization|protein localization to adherens junction|ventricular cardiac muscle cell action potential|bundle of His cell to Purkinje myocyte communication|regulation of heart rate by cardiac conduction|,"protein kinase C binding|structural molecule activity|protein binding|protein binding, bridging|poly(A) RNA binding|cell adhesion molecule binding|scaffold protein binding|",9,0.2,0.572,9,-0.3,1.75,0.2,1.64,1.64,0.675,0,0,-1.3,1.3
ENSMUSG00000027324,RPUSD2,RNA pseudouridylate synthase domain containing 2,cellular_component|,pseudouridine synthesis|RNA modification|,RNA binding|pseudouridine synthase activity|poly(A) RNA binding|,10,0.4,2.3,10,0.1,0.333,0.2,1.64,1.64,0.675,0,0,-1.1,1.6
ENSMUSG00000041791,CAPZA3,"capping protein (actin filament) muscle Z-line, alpha 3",acrosomal vesicle|acrosomal vesicle|nucleus|cytoplasm|F-actin capping protein complex|membrane|cortical cytoskeleton|WASH complex|,spermatid development|actin cytoskeleton organization|actin filament capping|,actin binding|,10,0.1,0.547,10,0.2,1.23,0.1,1.64,1.64,0.675,0,0,-1.3,1.2
ENSMUSG00000019789,HEY2,hairy/enhancer-of-split related with YRPW motif 2,nucleus|nucleus|transcription factor complex|cytoplasm|Sin3 complex|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|blood vessel development|vasculogenesis|muscular septum morphogenesis|outflow tract morphogenesis|atrioventricular valve development|pulmonary valve morphogenesis|tricuspid valve morphogenesis|tricuspid valve formation|endocardial cushion to mesenchymal transition involved in heart valve formation|cardiac ventricle morphogenesis|cardiac left ventricle morphogenesis|cardiac right ventricle morphogenesis|ventricular trabecula myocardium morphogenesis|cardiac muscle hypertrophy|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|pattern specification process|pattern specification process|anterior/posterior axis specification|positive regulation of heart rate|regulation of gene expression|negative regulation of gene expression|negative regulation of cardiac muscle cell apoptotic process|mesenchymal cell development|cardiac muscle hypertrophy in response to stress|ascending aorta morphogenesis|dorsal aorta morphogenesis|umbilical cord morphogenesis|cell fate commitment|regulation of auditory receptor cell differentiation|negative regulation of Notch signaling pathway|negative regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|ventricular cardiac muscle cell development|positive regulation of cardiac muscle cell proliferation|cardiac epithelial to mesenchymal transition|heart trabecula formation|cardiac septum morphogenesis|ventricular septum morphogenesis|atrial septum morphogenesis|negative regulation of transcription initiation from RNA polymerase II promoter|labyrinthine layer blood vessel development|artery development|arterial endothelial cell differentiation|cardiac vascular smooth muscle cell development|coronary vasculature morphogenesis|pulmonary artery morphogenesis|Notch signaling involved in heart development|protein-DNA complex assembly|cochlea development|cochlea development|negative regulation of transcription regulatory region DNA binding|negative regulation of transcription regulatory region DNA binding|negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|regulation of vasculogenesis|",RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|protein binding transcription factor activity|RNA polymerase II activating transcription factor binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|microsatellite binding|microsatellite binding|histone deacetylase binding|sequence-specific DNA binding|sequence-specific DNA binding|protein dimerization activity|,10,0,0,10,-0.4,2.57,-0.2,1.6,-1.6,0.679,0,0,-1.6,0.7
ENSMUSG00000035459,STAB2,stabilin 2,cytoplasm|plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,endocytosis|receptor-mediated endocytosis|cell adhesion|regulation of gene expression|regulation of blood coagulation|defense response to bacterium|,low-density lipoprotein receptor activity|scavenger receptor activity|hyaluronic acid binding|low-density lipoprotein particle binding|,10,-0.1,0.723,10,-0.1,0.972,-0.1,1.57,-1.57,0.683,0,0,-1.5,1.1
ENSMUSG00000034659,TMEM109,transmembrane protein 109,intracellular|nucleus|endoplasmic reticulum|membrane|integral component of membrane|sarcoplasmic reticulum|nuclear membrane|extracellular vesicular exosome|,intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of cell death|cellular response to gamma radiation|,protein binding|,10,0,0,10,0.3,2.6,0.2,1.57,1.57,0.683,0,0,-1,1.4
ENSMUSG00000035620,RIC8B,resistance to inhibitors of cholinesterase 8 homolog B (C. elegans),cytoplasm|centrosome|,None,guanyl-nucleotide exchange factor activity|,10,-0.3,0.576,10,0.1,1.33,0.1,1.55,1.55,0.686,0,0,-1.6,1.1
ENSMUSG00000003559,AS3MT,arsenic (+3 oxidation state) methyltransferase,cytoplasm|mitochondrion|cytosol|,toxin metabolic process|arsonoacetate metabolic process|methylation|response to arsenic-containing substance|response to arsenic-containing substance|,methyltransferase activity|transferase activity|arsenite methyltransferase activity|arsenite methyltransferase activity|methylarsonite methyltransferase activity|,10,0,0,10,0.4,3.24,0.4,1.54,1.54,0.687,0,0,-0.7,1.7
ENSMUSG00000063884,PTCD3,pentatricopeptide repeat domain 3,mitochondrion|mitochondrion|,regulation of translation|mitochondrial translation|,RNA binding|rRNA binding|ribosomal small subunit binding|poly(A) RNA binding|,10,0.4,1.61,10,-0.8,1.08,0.3,1.54,1.54,0.687,0,0,-1.8,1.2
ENSMUSG00000019992,MTFR2,mitochondrial fission regulator 2,mitochondrion|,mitochondrial fission|mitochondrion organization|aerobic respiration|,molecular_function|,10,-0.3,1.68,10,0.2,1.21,-0.4,1.54,-1.54,0.687,0,0,-1.7,0.7
ENSMUSG00000039716,DOCK3,dedicator of cyto-kinesis 3,cytoplasm|cytoplasm|,small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|protein binding|SH3 domain binding|,10,-0.2,0.904,10,0.3,1.55,-0.2,1.54,-1.54,0.687,0,0,-1.2,1.3
ENSMUSG00000001768,RIN2,Ras and Rab interactor 2,cellular_component|cytoplasm|,endocytosis|signal transduction|biological_process|,molecular_function|GTPase activator activity|,10,0,0,10,0.4,3.14,0.4,1.53,1.53,0.688,0,0,-0.6,1.7
ENSMUSG00000038807,RAP1GAP2,RAP1 GTPase activating protein 2,cytoplasm|cytoplasm|centrosome|nuclear membrane|neuron projection|,negative regulation of neuron projection development|negative regulation of neuron projection development|positive regulation of Rap GTPase activity|regulation of small GTPase mediated signal transduction|,GTPase activator activity|Rap GTPase activator activity|,10,-0.1,0.0655,10,0.3,2.5,0.2,1.53,1.53,0.688,0,0,-0.9,1.6
ENSMUSG00000089911,HIAT1,hippocampus abundant gene transcript 1,plasma membrane|membrane|integral component of membrane|,transport|carbohydrate transport|transmembrane transport|,transporter activity|,9,0,0,9,-0.3,3.73,-0.3,1.53,-1.53,0.688,0,0,-1.5,1
ENSMUSG00000039050,OSBPL2,oxysterol binding protein-like 2,cellular_component|,transport|lipid transport|biological_process|,lipid binding|cholesterol binding|,10,0.1,0.213,10,0.2,1.51,0.2,1.53,1.53,0.688,0,0,-1.4,1.1
ENSMUSG00000017664,SLC35C2,"solute carrier family 35, member C2",endoplasmic reticulum-Golgi intermediate compartment|cis-Golgi network|membrane|integral component of membrane|,transport|negative regulation of gene expression|fucosylation|protein O-linked fucosylation|protein O-linked fucosylation|positive regulation of Notch signaling pathway|,molecular_function|,10,0.4,0.298,10,0.2,1.74,0.2,1.52,1.52,0.689,0,0,-0.6,1.8
ENSMUSG00000006021,KPTN,kaptin,cellular_component|cytoplasm|cell projection|,biological_process|,molecular_function|actin binding|,10,-0.2,1.97,10,0.1,0.652,-0.2,1.52,-1.52,0.689,0,0,-1.1,1.4
ENSMUSG00000015314,SLAMF6,SLAM family member 6,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,None,receptor activity|,10,0.9,2.51,10,-0.3,2.46,-0.3,1.52,-1.52,0.689,0,0,-0.9,2
ENSMUSG00000018740,SLC25A35,"solute carrier family 25, member 35",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0.7,1.83,10,0.1,0.513,0.3,1.51,1.51,0.69,0,0,-0.3,1.9
ENSMUSG00000039844,RAPGEF1,Rap guanine nucleotide exchange factor (GEF) 1,early endosome|,blood vessel development|signal transduction|positive regulation of signal transduction|positive regulation of neuron projection development|single organismal cell-cell adhesion|Rap protein signal transduction|positive regulation of Rap GTPase activity|nerve growth factor signaling pathway|positive regulation of GTPase activity|negative regulation of Ras protein signal transduction|platelet-derived growth factor receptor signaling pathway|negative regulation of protein kinase B signaling|establishment of endothelial barrier|negative regulation of ERK1 and ERK2 cascade|cellular response to cAMP|negative regulation of canonical Wnt signaling pathway|regulation of cell junction assembly|cellular response to nerve growth factor stimulus|negative regulation of neural precursor cell proliferation|,signal transducer activity|SH3/SH2 adaptor activity|guanyl-nucleotide exchange factor activity|protein binding|Rap guanyl-nucleotide exchange factor activity|,10,0.1,0.433,10,-0.4,2.67,-0.2,1.5,-1.5,0.691,0,0,-1.6,0.9
ENSMUSG00000014633,CMC2,COX assembly mitochondrial protein 2,mitochondrion|,biological_process|,molecular_function|,10,0.3,2.09,10,-0.1,1.03,0.3,1.5,1.5,0.691,0,0,-0.8,1.5
ENSMUSG00000000740,RPL13,ribosomal protein L13,intracellular|nucleus|nucleolus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,6,0.3,0.318,7,0.4,1.4,0.3,1.49,1.49,0.692,0,0,-0.7,2
ENSMUSG00000022217,EMC9,ER membrane protein complex subunit 9,cytoplasm|ER membrane protein complex|,None,None,10,-0.3,2.62,10,0,0,-0.2,1.48,-1.48,0.694,0,0,-1.6,0.8
ENSMUSG00000027489,NECAB3,N-terminal EF-hand calcium binding protein 3,Golgi cis cisterna|Golgi cis cisterna|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|,protein metabolic process|protein metabolic process|regulation of amyloid precursor protein biosynthetic process|,calcium ion binding|protein binding|metal ion binding|,10,0.4,1.94,10,0,0,0.3,1.47,1.47,0.695,0,0,-0.6,1.6
ENSMUSG00000018882,MRPL45,mitochondrial ribosomal protein L45,mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,poly(A) RNA binding|,10,-0.1,0.513,10,-0.3,1.24,-0.2,1.47,-1.47,0.695,0,0,-1.6,0.7
ENSMUSG00000027739,RAB33B,"RAB33B, member RAS oncogene family",Golgi apparatus|Golgi lumen|Golgi lumen|membrane|extracellular vesicular exosome|,"transport|autophagy|small GTPase mediated signal transduction|protein transport|regulation of retrograde vesicle-mediated transport, Golgi to ER|regulation of autophagic vacuole assembly|",nucleotide binding|protein binding|GTP binding|,10,-0.1,0.147,10,-0.4,1.89,-0.3,1.46,-1.46,0.696,0,0,-1.6,0.8
ENSMUSG00000052911,LAMB2,"laminin, beta 2",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basal lamina|laminin-3 complex|laminin-3 complex|extracellular matrix|laminin complex|synapse|extracellular vesicular exosome|,cell morphogenesis involved in differentiation|cell adhesion|axon guidance|neuromuscular junction development|visual perception|astrocyte development|Schwann cell development|neuron projection development|axon extension involved in regeneration|synapse organization|retina development in camera-type eye|metanephric glomerular visceral epithelial cell development|metanephric glomerular basement membrane development|,integrin binding|,10,-0.1,0.398,10,-0.2,1.18,-0.2,1.45,-1.45,0.697,0,0,-1.4,1.1
ENSMUSG00000018322,TOMM34,translocase of outer mitochondrial membrane 34,nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|membrane|,protein targeting to mitochondrion|,protein binding|heat shock protein binding|,10,0.1,0.493,10,0.2,1.12,0.2,1.45,1.45,0.697,0,0,-0.6,1.7
ENSMUSG00000037010,APLN,apelin,extracellular space|perinuclear region of cytoplasm|,regulation of the force of heart contraction|signal transduction|G-protein coupled receptor signaling pathway|feeding behavior|positive regulation of cell proliferation|positive regulation of heat generation|positive regulation of phosphorylation|drinking behavior|regulation of respiratory gaseous exchange|negative regulation of blood pressure|negative regulation of vasoconstriction|positive regulation of vasodilation|regulation of body fluid levels|positive regulation of corticotropin secretion|positive regulation of corticotropin-releasing hormone secretion|,receptor binding|hormone activity|apelin receptor binding|,10,0.4,0.79,10,0.7,1.23,0.6,1.44,1.44,0.698,0,0,-0.4,1.9
ENSMUSG00000008206,CERS4,ceramide synthase 4,nucleus|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|sphingolipid biosynthetic process|ceramide biosynthetic process|,DNA binding|sphingosine N-acyltransferase activity|,10,-0.1,0.098,10,0.4,3.68,0.4,1.44,1.44,0.698,0,0,-0.6,1.7
ENSMUSG00000070979,ACTL7A,actin-like 7a,male germ cell nucleus|nucleus|cytoplasm|Golgi apparatus|cytoskeleton|motile cilium|protein complex|,None,None,10,-0.3,2.18,10,-0.1,0.218,-0.1,1.43,-1.43,0.7,0,0,-1.7,0.7
ENSMUSG00000067780,PI15,peptidase inhibitor 15,extracellular region|,negative regulation of peptidase activity|,peptidase inhibitor activity|,10,0.3,0.963,10,0.1,0.684,0.2,1.42,1.42,0.701,0,0,-0.7,1.6
ENSMUSG00000022106,RCBTB2,regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2,acrosomal vesicle|,biological_process|,molecular_function|,10,-0.4,2.04,10,-0.1,0.255,-0.2,1.42,-1.42,0.701,0,0,-1.9,0.5
ENSMUSG00000040543,PITPNM3,PITPNM family member 3,cellular_component|intracellular|membrane|,transport|biological_process|,lipid binding|metal ion binding|,10,-0.5,2.4,10,0.8,3.06,0.2,1.4,1.4,0.703,0,0,-1.3,1.8
ENSMUSG00000029233,SRD5A3,steroid 5 alpha-reductase 3,cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|,dolichol-linked oligosaccharide biosynthetic process|dolichol-linked oligosaccharide biosynthetic process|lipid metabolic process|polyprenol catabolic process|polyprenol catabolic process|dolichol metabolic process|dolichol metabolic process|oxidation-reduction process|,"3-oxo-5-alpha-steroid 4-dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor|cholestenone 5-alpha-reductase activity|",10,-0.3,1.49,10,0.1,0.152,-0.2,1.39,-1.39,0.704,0,0,-1.5,1
ENSMUSG00000026413,PKP1,plakophilin 1,nucleus|plasma membrane|cell junction|desmosome|intracellular membrane-bounded organelle|extracellular vesicular exosome|,cell adhesion|single organismal cell-cell adhesion|intermediate filament bundle assembly|,protein binding|lamin binding|,10,0,0,10,0.3,3.28,0.2,1.39,1.39,0.704,0,0,-0.7,1.7
ENSMUSG00000024851,PITPNM1,"phosphatidylinositol transfer protein, membrane-associated 1",intracellular|cytoplasm|endoplasmic reticulum|Golgi apparatus|lipid particle|membrane|,transport|protein transport|,phospholipid binding|metal ion binding|,10,0,0,10,0.2,2.2,0.2,1.38,1.38,0.706,0,0,-0.8,1.6
ENSMUSG00000044447,DOCK5,dedicator of cytokinesis 5,cytoplasm|,small GTPase mediated signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|,10,0.8,1.23,10,0.2,1.01,0.1,1.34,1.34,0.711,0,0,-0.4,2
ENSMUSG00000024327,SLC39A7,"solute carrier family 39 (zinc transporter), member 7",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,transport|ion transport|zinc ion transport|metal ion transport|transmembrane transport|,protein binding|metal ion transmembrane transporter activity|,9,0.3,2.28,10,-0.1,0.201,0.2,1.33,1.33,0.713,0,0,-0.8,1.6
ENSMUSG00000024972,LGALS12,"lectin, galactose binding, soluble 12",intracellular|nucleus|mitochondrion|,apoptotic process|intrinsic apoptotic signaling pathway|,carbohydrate binding|lactose binding|,10,0,0,10,0.2,1.57,0.2,1.33,1.33,0.713,0,0,-1,1.5
ENSMUSG00000030727,RABEP2,"rabaptin, RAB GTPase binding effector protein 2",nucleus|cytoplasm|endosome|,transport|endocytosis|protein transport|,GTPase activator activity|growth factor activity|,10,-0.1,0.076,10,-0.2,1.54,-0.1,1.32,-1.32,0.714,0,0,-1.2,1.5
ENSMUSG00000035172,PLEKHH3,"pleckstrin homology domain containing, family H (with MyTH4 domain) member 3",extracellular space|cytoskeleton|,signal transduction|biological_process|,molecular_function|,10,0.2,0.499,10,0.1,0.983,0.1,1.31,1.31,0.715,0,0,-1,1.5
ENSMUSG00000027247,ARHGAP1,Rho GTPase activating protein 1,ruffle|intracellular|cytoplasm|plasma membrane|cell leading edge|extracellular vesicular exosome|,signal transduction|small GTPase mediated signal transduction|positive regulation of Rho GTPase activity|positive regulation of Rac GTPase activity|regulation of GTPase activity|,GTPase activator activity|Rho GTPase activator activity|Rho GTPase activator activity|protein binding|SH3 domain binding|Rac GTPase activator activity|,10,-0.2,0.812,10,-0.2,0.601,-0.2,1.3,-1.3,0.716,0,0,-1.5,1
ENSMUSG00000019797,1700021F05RIK,RIKEN cDNA 1700021F05 gene,mitochondrion|mitochondrion|,biological_process|,molecular_function|,10,-0.2,0.914,10,-0.1,0.698,-0.2,1.3,-1.3,0.716,0,0,-1.6,0.9
ENSMUSG00000030222,RERG,"RAS-like, estrogen-regulated, growth-inhibitor",nucleus|cytoplasm|cytosol|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|negative regulation of cell proliferation|response to hormone|negative regulation of cell growth|,nucleotide binding|GTPase activity|GTP binding|,10,0,0,10,-0.2,1.88,-0.2,1.29,-1.29,0.718,0,0,-1.7,0.8
ENSMUSG00000027777,SCHIP1,schwannomin interacting protein 1,cytoplasm|,luteinization|kidney development|nitrogen compound metabolic process|estrogen metabolic process|female gonad development|post-embryonic development|fibroblast migration|platelet-derived growth factor receptor signaling pathway|skeletal system morphogenesis|smooth muscle tissue development|palate development|face morphogenesis|,protein binding|identical protein binding|protein homodimerization activity|,10,0.3,0.393,10,0.3,1.01,0.3,1.29,1.29,0.718,0,0,-0.6,1.8
ENSMUSG00000024471,MYOT,myotilin,cytoplasm|cytoskeleton|plasma membrane|membrane|Z disc|Z disc|,biological_process|,actin binding|alpha-actinin binding|,10,0.3,0.872,10,0.1,0.758,0.2,1.28,1.28,0.719,0,0,-1,1.4
ENSMUSG00000000359,REM1,rad and gem related GTP binding protein 1,cellular_component|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|biological_process|,nucleotide binding|calmodulin binding|GTP binding|,10,0.9,1.92,10,0.2,0.922,0.2,1.28,1.28,0.719,0,0,-0.2,2
ENSMUSG00000067424,ZFP563,zinc finger protein 563,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.3,1.22,10,0.1,0.316,0.2,1.28,1.28,0.719,0,0,-0.7,1.7
ENSMUSG00000022438,PARVB,"parvin, beta",cytoplasm|cytoskeleton|plasma membrane|focal adhesion|membrane|lamellipodium|cell junction|cell projection|,cell adhesion|cell projection assembly|lamellipodium assembly|actin cytoskeleton reorganization|establishment or maintenance of cell polarity regulating cell shape|,actin binding|protein binding|,10,-0.1,0.689,10,0.8,2.09,-0.1,1.27,-1.27,0.72,0,0,-0.7,2
ENSMUSG00000046095,KRT32,keratin 32,intermediate filament|,None,structural molecule activity|,10,0.2,0.889,10,0.1,0.503,0.2,1.27,1.27,0.72,0,0,-0.9,1.6
ENSMUSG00000037788,VOPP1,"vesicular, overexpressed in cancer, prosurvival protein 1",endosome|membrane|integral component of membrane|cytoplasmic vesicle membrane|integral component of organelle membrane|cytoplasmic vesicle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|",signal transducer activity|,10,0,0,10,-0.2,1.86,-0.2,1.26,-1.26,0.721,0,0,-1.6,0.9
ENSMUSG00000033355,RTP4,receptor transporter protein 4,cytoplasm|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|protein targeting to membrane|,molecular_function|,10,0.2,0.341,10,0.6,1.43,0.4,1.25,1.25,0.723,0,0,-0.5,1.8
ENSMUSG00000038831,RALGPS1,Ral GEF with PH domain and SH3 binding motif 1,cellular_component|cytoplasm|plasma membrane|membrane|,small GTPase mediated signal transduction|regulation of Ral protein signal transduction|positive regulation of Ral GTPase activity|,guanyl-nucleotide exchange factor activity|Ral guanyl-nucleotide exchange factor activity|,10,-0.1,0.945,10,-0.1,0.388,-0.1,1.23,-1.23,0.725,0,0,-1.6,0.9
ENSMUSG00000030747,DGAT2,diacylglycerol O-acyltransferase 2,mitochondrion|endoplasmic reticulum|endoplasmic reticulum|lipid particle|membrane|integral component of membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,glycerol metabolic process|lipid metabolic process|triglyceride biosynthetic process|triglyceride biosynthetic process|triglyceride biosynthetic process|lipid storage|lipid storage|low-density lipoprotein particle clearance|long-chain fatty-acyl-CoA metabolic process|long-chain fatty-acyl-CoA metabolic process|cellular triglyceride homeostasis|cholesterol homeostasis|diacylglycerol metabolic process|diacylglycerol metabolic process|fatty acid homeostasis|fat pad development|cellular response to oleic acid|regulation of plasma lipoprotein particle levels|,"2-acylglycerol O-acyltransferase activity|diacylglycerol O-acyltransferase activity|diacylglycerol O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|protein homodimerization activity|retinol O-fatty-acyltransferase activity|",10,0.7,1.88,10,0.1,0.0906,0.1,1.23,1.23,0.725,0,0,-0.4,2
ENSMUSG00000018672,COPZ2,"coatomer protein complex, subunit zeta 2",cytoplasm|Golgi apparatus|membrane|COPI vesicle coat|COPI-coated vesicle|cytoplasmic vesicle|,transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|,10,0,0,10,0.3,2.22,0.2,1.23,1.23,0.725,0,0,-0.7,1.7
ENSMUSG00000026592,TEX35,testis expressed 35,nucleus|microtubule cytoskeleton|,biological_process|,molecular_function|,10,-0.8,1.09,10,0.5,1.05,0.2,1.22,1.22,0.727,0,0,-1.8,1.3
ENSMUSG00000045917,6330416G13RIK,RIKEN cDNA 6330416G13 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,1.27,10,0.1,0.484,-0.2,1.2,-1.2,0.729,0,0,-1.1,1.6
ENSMUSG00000038180,SPAG4,sperm associated antigen 4,cytoplasm|cytoskeleton|microtubule|cilium|membrane|integral component of membrane|cell projection|,biological_process|,identical protein binding|,10,0.3,1.72,10,0,0,0.3,1.2,1.2,0.729,0,0,-0.7,1.7
ENSMUSG00000001089,LUZP1,leucine zipper protein 1,nucleus|membrane|,ventricular septum development|neural fold bending|artery development|,molecular_function|,10,0,0,10,0.2,1.94,0.2,1.18,1.18,0.732,0,0,-0.7,1.8
ENSMUSG00000039457,PPL,periplakin,nucleus|cytoplasm|mitochondrion|cytoskeleton|plasma membrane|membrane|extrinsic component of plasma membrane|cell junction|extracellular vesicular exosome|,keratinization|,protein binding|,10,-0.1,0.0634,10,0.1,1.68,0.1,1.18,1.18,0.732,0,0,-1.2,1.5
ENSMUSG00000023216,EPB4.2,erythrocyte protein band 4.2,cytoplasm|cytoskeleton|plasma membrane|membrane|cortical cytoskeleton|,cell morphogenesis|regulation of cell shape|peptide cross-linking|hemoglobin metabolic process|erythrocyte maturation|spleen development|ion homeostasis|iron ion homeostasis|,protein-glutamine gamma-glutamyltransferase activity|,10,-0.1,0.219,10,-0.3,1.38,-0.2,1.17,-1.17,0.733,0,0,-1.6,0.9
ENSMUSG00000058420,SYT17,synaptotagmin XVII,trans-Golgi network|synaptic vesicle|membrane|,transport|exocytosis|biological_process|,molecular_function|transporter activity|,10,0.2,1.17,10,-0.9,1.22,0.2,1.17,1.17,0.733,0,0,-2,1
ENSMUSG00000079055,SLC8A3,"solute carrier family 8 (sodium/calcium exchanger), member 3",mitochondrion|microtubule|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|sarcolemma|cell projection|neuronal cell body|dendritic spine|,hematopoietic progenitor cell differentiation|sodium ion transport|metal ion transport|sodium ion transmembrane transport|calcium ion transport into cytosol|calcium ion transmembrane transport|cellular response to cAMP|calcium ion export from cell|calcium ion import into cell|,calcium:sodium antiporter activity|calcium:cation antiporter activity|,10,0,0,10,0.4,3.03,0.4,1.15,1.15,0.736,0,0,-0.5,1.9
ENSMUSG00000041360,D19BWG1357E,"DNA segment, Chr 19, Brigham & Women's Genetics 1357 expressed",nucleus|nucleolus|endoplasmic reticulum|,biological_process|,RNA binding|poly(A) RNA binding|,10,0.9,2.14,10,0.1,0.261,0.2,1.12,1.12,0.74,0,0,-0.3,2
ENSMUSG00000052852,REEP1,receptor accessory protein 1,cytoplasm|mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|,protein insertion into membrane|endoplasmic reticulum tubular network organization|,microtubule binding|olfactory receptor binding|,10,1,3.96,10,-0.5,3.69,-0.4,1.11,-1.11,0.742,0,0,-1,2
ENSMUSG00000028148,THEM5,thioesterase superfamily member 5,mitochondrion|mitochondrial matrix|,lipid metabolic process|fatty acid metabolic process|long-chain fatty-acyl-CoA metabolic process|cardiolipin acyl-chain remodeling|,palmitoyl-CoA hydrolase activity|hydrolase activity|,10,0,0,10,-0.6,3.4,-0.4,1.11,-1.11,0.742,0,0,-1.9,0.6
ENSMUSG00000029442,WDR66,WD repeat domain 66,cellular_component|,biological_process|,molecular_function|,9,0.2,0.5,10,0.2,0.692,0.2,1.1,1.1,0.743,0,0,-1,1.7
ENSMUSG00000066877,NCK2,non-catalytic region of tyrosine kinase adaptor protein 2,cytoplasm|endoplasmic reticulum|vesicle membrane|,regulation of translation|actin filament organization|cell migration|lamellipodium assembly|positive regulation of actin filament polymerization|positive regulation of T cell proliferation|positive regulation of transcription from RNA polymerase II promoter|,None,10,-0.1,0.282,10,0.2,2.06,0.1,1.09,1.09,0.744,0,0,-1.4,1.3
ENSMUSG00000047565,ACOT10,acyl-CoA thioesterase 10,mitochondrion|mitochondrion|,acyl-CoA metabolic process|,"CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0.4,2.16,10,0.1,0.0156,0.3,1.08,1.08,0.746,0,0,-0.4,1.9
ENSMUSG00000044294,KRT84,keratin 84,intermediate filament|keratin filament|intermediate filament cytoskeleton|,regulation of keratinocyte differentiation|,structural molecule activity|structural constituent of epidermis|,10,0,0,10,0.3,2.71,0.2,1.08,1.08,0.746,0,0,-0.7,1.7
ENSMUSG00000054146,KRT15,keratin 15,nucleus|intermediate filament|extracellular vesicular exosome|,None,structural molecule activity|scaffold protein binding|,10,0.1,0.0679,10,0.2,1.37,0.2,1.07,1.07,0.747,0,0,-1.1,1.4
ENSMUSG00000025733,RHOT2,"ras homolog gene family, member T2",intracellular|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|extracellular vesicular exosome|,small GTPase mediated signal transduction|cellular homeostasis|mitochondrion transport along microtubule|mitochondrial outer membrane permeabilization|,nucleotide binding|GTPase activity|calcium ion binding|GTP binding|hydrolase activity|metal ion binding|,10,0,0,10,0.2,1.35,0.2,1.07,1.07,0.747,0,0,-0.9,1.6
ENSMUSG00000050138,KCNK12,"potassium channel, subfamily K, member 12",cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.1,0.167,10,0.1,0.98,0.1,1.06,1.06,0.749,0,0,-0.9,1.7
ENSMUSG00000053461,HHIPL2,hedgehog interacting protein-like 2,cellular_component|extracellular region|,carbohydrate metabolic process|biological_process|,"molecular_function|catalytic activity|oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor|quinone binding|",10,0,0,10,0.2,1.85,0.2,1.06,1.06,0.749,0,0,-0.8,1.7
ENSMUSG00000050989,SEPN1,"selenoprotein N, 1",cellular_component|,respiratory system process|mitochondrion organization|skeletal muscle satellite cell differentiation|positive regulation of skeletal muscle cell proliferation|response to muscle activity involved in regulation of muscle adaptation|multicellular organismal response to stress|cellular response to oxidative stress|skeletal muscle tissue regeneration|lung alveolus development|skeletal muscle fiber development|cellular response to caffeine|,molecular_function|,10,0.1,0.211,10,0.2,0.976,0.1,1.06,1.06,0.749,0,0,-0.6,1.8
ENSMUSG00000006191,CDKAL1,CDK5 regulatory subunit associated protein 1-like 1,endoplasmic reticulum|rough endoplasmic reticulum|membrane|membrane|integral component of membrane|,tRNA processing|RNA modification|tRNA methylthiolation|macromolecule modification|maintenance of translational fidelity|,"catalytic activity|transferase activity|N6-threonylcarbomyladenosine methylthiotransferase activity|Kdo transferase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0,0,10,0.3,2.45,0.2,1.05,1.05,0.75,0,0,-1,1.6
ENSMUSG00000060012,KIF13B,kinesin family member 13B,cytoplasm|microtubule|axon|,regulation of axonogenesis|,nucleotide binding|ATP binding|protein kinase binding|14-3-3 protein binding|,10,0,0,10,0.3,2.15,0.2,1.05,1.05,0.75,0,0,-0.8,1.7
ENSMUSG00000008734,GPRC5B,"G protein-coupled receptor, family C, group 5, member B",extracellular space|nucleus|nucleolus|plasma membrane|cell surface|membrane|integral component of membrane|intracellular membrane-bounded organelle|membrane raft|membrane raft|extracellular vesicular exosome|,positive regulation of protein phosphorylation|signal transduction|G-protein coupled receptor signaling pathway|locomotory behavior|positive regulation of neuron projection development|glucose homeostasis|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of neuron differentiation|positive regulation of protein kinase activity|positive regulation of protein kinase activity|positive regulation of inflammatory response|positive regulation of macrophage cytokine production|positive regulation of protein tyrosine kinase activity|positive regulation of canonical Wnt signaling pathway|,signal transducer activity|G-protein coupled receptor activity|protein kinase binding|protein kinase binding|protein kinase activator activity|,10,-0.1,0.206,10,-0.5,1.68,-0.3,1.04,-1.04,0.751,0,0,-1.6,1.3
ENSMUSG00000027624,EPB4.1L1,erythrocyte protein band 4.1-like 1,cytoplasm|cytoskeleton|extrinsic component of membrane|protein complex|synaptic membrane|,cortical actin cytoskeleton organization|,actin binding|receptor binding|structural molecule activity|protein binding|cytoskeletal protein binding|,10,0,0,10,-1,1.7,0.2,1.04,1.04,0.751,0,0,-2,0.9
ENSMUSG00000025931,PAQR8,progestin and adipoQ receptor family member VIII,plasma membrane|membrane|integral component of membrane|,multicellular organismal development|cell differentiation|steroid hormone mediated signaling pathway|oogenesis|response to steroid hormone|,steroid hormone receptor activity|steroid binding|lipid binding|,10,0.3,0.939,10,-0.5,0.741,0.1,1.03,1.03,0.753,0,0,-1.6,1.2
ENSMUSG00000021879,DNAH12,"dynein, axonemal, heavy chain 12",cellular_component|cytoplasm|cytoskeleton|microtubule|cilium|dynein complex|cell projection|,microtubule-based movement|biological_process|,nucleotide binding|molecular_function|motor activity|microtubule motor activity|ATP binding|ATPase activity|,10,0.4,1.37,10,0,0,0.4,1.03,1.03,0.753,0,0,-0.6,1.8
ENSMUSG00000074643,CPNE1,copine I,extracellular vesicular exosome|,biological_process|,phosphatidylserine binding|protein binding|,10,0,0,10,0.2,2.04,0.2,1.01,1.01,0.756,0,0,-1.1,1.5
ENSMUSG00000060187,LRRC10,leucine rich repeat containing 10,nucleus|mitochondrion|cytoskeleton|myofibril|sarcomere|,cardiac muscle cell development|,actin binding|alpha-actinin binding|,10,0.1,0.0224,10,-0.2,1.46,-0.1,1,-1,0.757,0,0,-1.3,1.4
ENSMUSG00000048065,CYB5R2,cytochrome b5 reductase 2,nucleus|mitochondrion|membrane|,lipid metabolic process|steroid biosynthetic process|steroid metabolic process|sterol biosynthetic process|oxidation-reduction process|,"cytochrome-b5 reductase activity, acting on NAD(P)H|oxidoreductase activity|",10,-0.1,0.381,10,0.2,1.01,0.1,0.991,0.991,0.759,0,0,-1.1,1.5
ENSMUSG00000034006,PQLC1,PQ loop repeat containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.755,10,0.1,0.408,0.2,0.99,0.99,0.759,0,0,-1.3,1.4
ENSMUSG00000036123,SLC9A3,"solute carrier family 9 (sodium/hydrogen exchanger), member 3",plasma membrane|plasma membrane|brush border|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|brush border membrane|brush border membrane|membrane-bounded vesicle|extracellular vesicular exosome|,regulation of sodium ion transport|transport|ion transport|sodium ion transport|sodium ion transport|regulation of pH|regulation of pH|receptor-mediated endocytosis|sodium ion transmembrane transport|sodium ion transmembrane transport|hydrogen ion transmembrane transport|,antiporter activity|sodium:proton antiporter activity|sodium:proton antiporter activity|PDZ domain binding|,10,0.1,0.349,10,0.2,0.791,0.2,0.989,0.989,0.759,0,0,-1,1.6
ENSMUSG00000017747,GHDC,GH3 domain containing,nucleus|endoplasmic reticulum|membrane|,None,None,10,0.3,1.37,10,0.1,0.214,0.1,0.987,0.987,0.759,0,0,-0.8,1.7
ENSMUSG00000048442,SMIM5,small integral membrane protein 5,membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.6,2.29,9,0.9,2.92,-0.2,0.986,-0.986,0.76,0,0,-1.3,2
ENSMUSG00000021687,SCAMP1,secretory carrier membrane protein 1,cell|endosome|Golgi apparatus|trans-Golgi network|synaptic vesicle|membrane|integral component of membrane|clathrin-coated vesicle|synaptic vesicle membrane|zymogen granule membrane|synapse|recycling endosome membrane|,transport|exocytosis|endocytosis|protein transport|,protein binding|protein domain specific binding|,10,0.3,1.25,10,0.1,0.217,0.2,0.985,0.985,0.76,0,0,-0.6,1.8
ENSMUSG00000025816,SEC61A2,"Sec61, alpha subunit 2 (S. cerevisiae)",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,transport|protein transport|,ribosome binding|,10,0.1,0.0934,10,0.2,1.03,0.2,0.978,0.978,0.761,0,0,-0.9,1.6
ENSMUSG00000019853,HEBP2,heme binding protein 2,cytoplasm|cytoplasm|mitochondrion|extracellular vesicular exosome|,negative regulation of mitochondrial membrane potential|positive regulation of necrotic cell death|positive regulation of mitochondrial membrane permeability|,molecular_function|,10,0.1,0.19,10,0.1,0.87,0.1,0.977,0.977,0.761,0,0,-1.4,1.4
ENSMUSG00000049422,CHCHD10,coiled-coil-helix-coiled-coil-helix domain containing 10,mitochondrion|mitochondrion|,oxidative phosphorylation|ATP biosynthetic process|negative regulation of ATP citrate synthase activity|,molecular_function|,10,0.8,2.64,10,-0.1,1.08,-0.1,0.968,-0.968,0.762,0,0,-0.6,2
ENSMUSG00000070704,UGT2B36,"UDP glucuronosyltransferase 2 family, polypeptide B36",intracellular membrane-bounded organelle|extracellular vesicular exosome|,biological_process|,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,10,0.5,3.17,0.4,0.962,0.962,0.763,0,0,-0.8,1.8
ENSMUSG00000042148,COX10,cytochrome c oxidase assembly protein 10,mitochondrion|mitochondrion|membrane|integral component of membrane|mitochondrial membrane|,mitochondrial fission|heme biosynthetic process|heme a biosynthetic process|heme a biosynthetic process|heme a biosynthetic process|mitochondrion organization|respiratory chain complex IV assembly|aerobic respiration|cytochrome complex assembly|protein farnesylation|cellular respiration|heme O biosynthetic process|hydrogen ion transmembrane transport|,"cytochrome-c oxidase activity|farnesyltranstransferase activity|prenyltransferase activity|protein geranylgeranyltransferase activity|protein prenyltransferase activity|4-hydroxybenzoate octaprenyltransferase activity|protoheme IX farnesyltransferase activity|transferase activity|(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity|cadaverine aminopropyltransferase activity|agmatine aminopropyltransferase activity|1,4-dihydroxy-2-naphthoate octaprenyltransferase activity|trans-pentaprenyltranstransferase activity|ATP dimethylallyltransferase activity|ADP dimethylallyltransferase activity|",9,0,0,9,0.2,1.35,0.1,0.961,0.961,0.763,0,0,-1.4,1.4
ENSMUSG00000037994,SLC9B2,"solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2",mitochondrion|membrane|integral component of membrane|,transport|ion transport|cation transport|sodium ion transport|proton transport|transmembrane transport|,antiporter activity|solute:proton antiporter activity|,10,0.1,0.0525,10,0.1,0.979,0.1,0.955,0.955,0.764,0,0,-1,1.6
ENSMUSG00000003721,INSIG2,insulin induced gene 2,endoplasmic reticulum|membrane|integral component of membrane|SREBP-SCAP-Insig complex|,lipid metabolic process|triglyceride metabolic process|cholesterol biosynthetic process|response to sterol depletion|steroid metabolic process|cholesterol metabolic process|negative regulation of steroid biosynthetic process|sterol biosynthetic process|SREBP signaling pathway|inner ear morphogenesis|middle ear morphogenesis|negative regulation of fatty acid biosynthetic process|palate development|cranial suture morphogenesis|,protein binding|transcription factor binding|,10,0,0,10,0.2,1.4,0.1,0.953,0.953,0.764,0,0,-1,1.7
ENSMUSG00000022629,KIF21A,kinesin family member 21A,cytoplasm|cytoskeleton|kinesin complex|microtubule|cell projection|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,0.4,1.52,10,0,0,0.2,0.949,0.949,0.765,0,0,-0.5,1.8
ENSMUSG00000079469,PIGB,"phosphatidylinositol glycan anchor biosynthesis, class B",endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|membrane|integral component of membrane|,GPI anchor metabolic process|GPI anchor biosynthetic process|mannosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.2,0.989,10,-0.1,0.254,-0.1,0.936,-0.936,0.767,0,0,-1.5,1.2
ENSMUSG00000043003,RASEF,RAS and EF hand domain containing,cellular_component|cytoplasm|,small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTP binding|,10,0,0,10,0.7,3.39,0.2,0.93,0.93,0.768,0,0,-1,1.9
ENSMUSG00000063558,AOX1,aldehyde oxidase 1,cytoplasm|extracellular vesicular exosome|,oxidation-reduction process|,"catalytic activity|aldehyde oxidase activity|aldehyde oxidase activity|iron ion binding|UDP-N-acetylmuramate dehydrogenase activity|electron carrier activity|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|molybdopterin cofactor binding|metal ion binding|flavin adenine dinucleotide binding|NAD binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,0.2,0.582,10,0.1,0.439,0.2,0.923,0.923,0.769,0,0,-0.9,1.7
ENSMUSG00000001507,ITGA3,integrin alpha 3,plasma membrane|plasma membrane|integrin complex|external side of plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|growth cone|integrin alpha3-beta1 complex|receptor complex|synapse|perinuclear region of cytoplasm|extracellular vesicular exosome|,neuron migration|cell adhesion|integrin-mediated signaling pathway|memory|positive regulation of gene expression|positive regulation of epithelial cell migration|positive regulation of cell-substrate adhesion|positive regulation of neuron projection development|negative regulation of cell projection organization|,fibronectin binding|integrin binding|protein binding|collagen binding|protein domain specific binding|laminin binding|protein heterodimerization activity|,10,0.1,0.17,10,0.2,0.843,0.2,0.92,0.92,0.769,0,0,-0.9,1.7
ENSMUSG00000033991,TTC37,tetratricopeptide repeat domain 37,nucleus|cytoplasm|transcriptionally active chromatin|Ski complex|,biological_process|,molecular_function|,9,0.1,0.255,9,0.2,0.775,0.2,0.916,0.916,0.77,0,0,-1,1.7
ENSMUSG00000048027,RGMB,repulsive guidance molecule family member B,endoplasmic reticulum-Golgi intermediate compartment|plasma membrane|membrane|anchored component of membrane|anchored component of plasma membrane|,"cell adhesion|signal transduction|BMP signaling pathway|positive regulation of transcription, DNA-templated|",identical protein binding|,10,-0.1,0.0517,10,-0.2,1.05,-0.2,0.914,-0.914,0.77,0,0,-1.5,1.1
ENSMUSG00000042523,DNAL1,"dynein, axonemal, light chain 1",cellular_component|,biological_process|,molecular_function|,10,0.2,0.592,10,0.1,0.432,0.1,0.905,0.905,0.772,0,0,-0.9,1.8
ENSMUSG00000002831,PLIN4,perilipin 4,cytoplasm|lipid particle|plasma membrane|membrane|,None,None,10,0,0,10,0.2,1.9,0.2,0.896,0.896,0.773,0,0,-0.8,1.7
ENSMUSG00000020334,SLC22A4,"solute carrier family 22 (organic cation transporter), member 4",mitochondrion|mitochondrion|membrane|integral component of membrane|apical plasma membrane|,amino acid transmembrane transport|triglyceride metabolic process|transport|ion transport|sodium ion transport|carnitine metabolic process|organic cation transport|organic cation transport|quaternary ammonium group transport|quaternary ammonium group transport|carnitine transport|carnitine transport|ion transmembrane transport|transmembrane transport|modified amino acid transport|carnitine transmembrane transport|carnitine transmembrane transport|,nucleotide binding|transporter activity|ATP binding|ion transmembrane transporter activity|organic cation transmembrane transporter activity|carnitine transmembrane transporter activity|carnitine transmembrane transporter activity|symporter activity|cation:cation antiporter activity|quaternary ammonium group transmembrane transporter activity|transmembrane transporter activity|PDZ domain binding|,10,0,0,10,0.9,3.72,0.9,0.888,0.888,0.774,0,0,-0.2,2
ENSMUSG00000000194,GPR107,G protein-coupled receptor 107,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.09,10,0.1,0.724,0.1,0.887,0.887,0.775,0,0,-1,1.8
ENSMUSG00000022867,USP25,ubiquitin specific peptidase 25,proteasome complex|nucleus|cytoplasm|,proteolysis|ubiquitin-dependent protein catabolic process|protein K63-linked deubiquitination|protein K48-linked deubiquitination|,ubiquitin-specific protease activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|SUMO binding|ubiquitinyl hydrolase activity|,10,0.4,1.45,10,0,0,0.1,0.883,0.883,0.775,0,0,-0.6,1.9
ENSMUSG00000032330,COX7A2,cytochrome c oxidase subunit VIIa 2,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain|membrane|extracellular vesicular exosome|,biological_process|,molecular_function|cytochrome-c oxidase activity|electron carrier activity|,10,-0.1,0.0944,10,-0.2,0.982,-0.1,0.88,-0.88,0.776,0,0,-1.6,1.1
ENSMUSG00000086784,ISOC2A,isochorismatase domain containing 2a,nucleus|cytoplasm|mitochondrion|,metabolic process|protein destabilization|,molecular_function|catalytic activity|,10,0.3,1.4,10,0.1,0.291,0.1,0.871,0.871,0.777,0,0,-1,1.6
ENSMUSG00000029557,FTSJ2,FtsJ homolog 2 (E. coli),nucleus|nucleolus|mitochondrion|,RNA methylation|rRNA processing|rRNA methylation|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,0.191,10,0.3,1.11,0.2,0.866,0.866,0.778,0,0,-1.5,1.2
ENSMUSG00000098207,ARL14,ADP-ribosylation factor-like 14,cellular_component|intracellular|cytoplasmic vesicle|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0,0,10,-0.1,0.969,-0.1,0.836,-0.836,0.783,0,0,-1.5,1.2
ENSMUSG00000034891,SNCB,"synuclein, beta",nucleus|cytoplasm|mitochondrion|Golgi apparatus|growth cone|neuronal cell body|terminal bouton|axon terminus|synapse|,synaptic transmission|dopamine metabolic process|negative regulation of neuron apoptotic process|synapse organization|,calcium ion binding|alpha-tubulin binding|beta-tubulin binding|,10,0,0,10,0.2,1.45,0.1,0.835,0.835,0.783,0,0,-0.9,1.7
ENSMUSG00000044150,A830080D01RIK,RIKEN cDNA A830080D01 gene,cellular_component|mitochondrion|,biological_process|,molecular_function|,9,0,0,9,0.2,1.37,0.1,0.824,0.824,0.784,0,0,-1.1,1.7
ENSMUSG00000027953,SLC50A1,"solute carrier family 50 (sugar transporter), member 1",nucleus|Golgi apparatus|plasma membrane|endomembrane system|membrane|integral component of membrane|,"DNA recombination|transport|carbohydrate transport|glucoside transport|positive regulation of gene expression, epigenetic|transmembrane transport|",glucoside transmembrane transporter activity|,10,0.5,1.49,10,0.1,0.195,0.3,0.822,0.822,0.785,0,0,-0.6,1.8
ENSMUSG00000036908,UNC93B1,unc-93 homolog B1 (C. elegans),intracellular|cell|lysosome|endosome|endosome|endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|cytoplasmic vesicle|early phagosome|,toll-like receptor signaling pathway|immune system process|intracellular protein transport|antigen processing and presentation of exogenous peptide antigen via MHC class II|toll-like receptor 3 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 7 signaling pathway|toll-like receptor 7 signaling pathway|toll-like receptor 9 signaling pathway|toll-like receptor 9 signaling pathway|innate immune response|defense response to virus|,protein binding|Toll-like receptor binding|,10,-0.1,0.326,10,-0.1,0.567,-0.1,0.82,-0.82,0.785,0,0,-1.6,1.1
ENSMUSG00000000325,ARVCF,armadillo repeat gene deleted in velo-cardio-facial syndrome,nucleus|cytoplasm|plasma membrane|,cell adhesion|multicellular organismal development|single organismal cell-cell adhesion|calcium-dependent cell-cell adhesion|,protein binding|,10,0.1,0.24,10,0.2,0.756,0.2,0.813,0.813,0.786,0,0,-0.9,1.7
ENSMUSG00000044807,ZFP354C,zinc finger protein 354C,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.2,0.54,10,0.2,0.346,0.2,0.813,0.813,0.786,0,0,-1,1.6
ENSMUSG00000028601,ECHDC2,enoyl Coenzyme A hydratase domain containing 2,cellular_component|mitochondrion|,lipid metabolic process|fatty acid metabolic process|metabolic process|,catalytic activity|lyase activity|,10,0.2,0.887,10,0,0,0.2,0.809,0.809,0.787,0,0,-0.7,1.8
ENSMUSG00000027487,CDK5RAP1,CDK5 regulatory subunit associated protein 1,cellular_component|cytoplasm|,regulation of cyclin-dependent protein serine/threonine kinase activity|tRNA modification|RNA modification|macromolecule modification|negative regulation of cyclin-dependent protein serine/threonine kinase activity|,"catalytic activity|transferase activity|protein complex binding|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.2,0.625,10,-0.2,2.22,-0.2,0.807,-0.807,0.787,0,0,-1.3,1.4
ENSMUSG00000040532,ABHD11,abhydrolase domain containing 11,mitochondrion|,biological_process|,molecular_function|catalytic activity|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0.1,0.361,10,0.2,0.624,0.1,0.805,0.805,0.788,0,0,-0.8,1.8
ENSMUSG00000023755,RHEBL1,Ras homolog enriched in brain like 1,cytoplasm|plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|TOR signaling|positive regulation of NF-kappaB transcription factor activity|,nucleotide binding|GTP binding|,10,-0.1,0.272,10,0.6,2.33,0.1,0.804,0.804,0.788,0,0,-0.6,2
ENSMUSG00000047415,GPR68,G protein-coupled receptor 68,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of insulin secretion|positive regulation of insulin secretion involved in cellular response to glucose stimulus|negative regulation of monocyte differentiation|cellular response to pH|positive regulation of osteoclast development|,signal transducer activity|G-protein coupled receptor activity|,10,0.1,0.048,10,-0.2,1.7,-0.1,0.804,-0.804,0.788,0,0,-1.4,1.4
ENSMUSG00000019158,TMEM160,transmembrane protein 160,mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.16,10,0,0,0.1,0.8,0.8,0.788,0,0,-1,1.7
ENSMUSG00000014444,PIEZO1,piezo-type mechanosensitive ion channel component 1,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|cation transport|positive regulation of integrin activation|positive regulation of cell-cell adhesion mediated by integrin|ion transmembrane transport|regulation of membrane potential|detection of mechanical stimulus|,cation channel activity|cation channel activity|mechanically-gated ion channel activity|,10,0,0,10,0.1,1,0.1,0.795,0.795,0.789,0,0,-1.2,1.5
ENSMUSG00000022964,TMEM50B,transmembrane protein 50B,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,None,None,10,0,0,10,0.7,3.28,0.1,0.784,0.784,0.791,0,0,-0.3,2
ENSMUSG00000005674,TOMM40L,translocase of outer mitochondrial membrane 40 homolog-like (yeast),mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|protein complex|pore complex|,transport|ion transport|biological_process|protein transport|transmembrane transport|,molecular_function|porin activity|,10,0.1,0.418,10,0.2,0.55,0.1,0.784,0.784,0.791,0,0,-1,1.6
ENSMUSG00000047719,UBIAD1,UbiA prenyltransferase domain containing 1,nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,ubiquinone biosynthetic process|menaquinone biosynthetic process|vitamin K biosynthetic process|,"prenyltransferase activity|protein geranylgeranyltransferase activity|protein prenyltransferase activity|4-hydroxybenzoate octaprenyltransferase activity|protoheme IX farnesyltransferase activity|antioxidant activity|transferase activity|(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity|cadaverine aminopropyltransferase activity|agmatine aminopropyltransferase activity|1,4-dihydroxy-2-naphthoate octaprenyltransferase activity|trans-pentaprenyltranstransferase activity|ATP dimethylallyltransferase activity|ADP dimethylallyltransferase activity|",10,0,0,10,0.2,1.94,0.1,0.779,0.779,0.792,0,0,-0.9,1.7
ENSMUSG00000056328,MYH1,"myosin, heavy polypeptide 1, skeletal muscle, adult",cytoplasm|muscle myosin complex|intercalated disc|myosin complex|A band|myosin filament|cytoplasmic ribonucleoprotein granule|,muscle contraction|,nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|,10,-0.7,2.38,10,-0.1,0.464,-0.2,0.777,-0.777,0.792,0,0,-2,0.4
ENSMUSG00000022704,QTRTD1,queuine tRNA-ribosyltransferase domain containing 1,cytoplasm|mitochondrion|,tRNA modification|tRNA processing|queuosine biosynthetic process|,"protein binding|zinc ion binding|queuine tRNA-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-0.1,0.274,10,0.4,2.06,0.3,0.739,0.739,0.798,0,0,-0.7,1.8
ENSMUSG00000017670,ELMO2,engulfment and cell motility 2,cytoplasm|cytosol|cytoskeleton|membrane|,phagocytosis|apoptotic process|cell chemotaxis|,SH3 domain binding|receptor tyrosine kinase binding|,10,0,0,10,0.3,2.04,0.2,0.739,0.739,0.798,0,0,-0.7,1.8
ENSMUSG00000024818,SLC25A45,"solute carrier family 25, member 45",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0.1,0.471,10,0.1,0.335,0.1,0.738,0.738,0.798,0,0,-1,1.7
ENSMUSG00000025026,ADD3,adducin 3 (gamma),condensed nuclear chromosome|cytoplasm|cytoskeleton|cytoskeleton|plasma membrane|cell-cell junction|cell cortex|membrane|,response to drug|,actin binding|protein kinase C binding|structural molecule activity|calmodulin binding|,10,0.1,0.000389,10,0.2,1.04,0.2,0.737,0.737,0.799,0,0,-0.5,2
ENSMUSG00000032548,SLCO2A1,"solute carrier organic anion transporter family, member 2a1",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|prostaglandin transport|ion transmembrane transport|,transporter activity|prostaglandin transmembrane transporter activity|,10,0.3,0.865,10,0.1,0.0498,0.2,0.73,0.73,0.8,0,0,-0.5,1.9
ENSMUSG00000002365,SNX9,sorting nexin 9,intracellular|cell|cytoplasm|cytoplasm|endosome|Golgi apparatus|trans-Golgi network|plasma membrane|plasma membrane|membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic membrane-bounded vesicle|clathrin-coated vesicle|cytoplasmic vesicle membrane|extrinsic component of cytoplasmic side of plasma membrane|cytoplasmic vesicle|cell projection|extracellular vesicular exosome|,mitotic cytokinesis|transport|intracellular protein transport|intracellular protein transport|endocytosis|receptor-mediated endocytosis|cell cycle|mitotic nuclear division|protein transport|endosomal transport|positive regulation of protein oligomerization|cleavage furrow formation|positive regulation of GTPase activity|cell division|lipid tube assembly|,protein binding|1-phosphatidylinositol binding|lipid binding|ubiquitin protein ligase binding|phosphatidylinositol binding|protein homodimerization activity|,10,0,0,10,0.1,1.13,0.1,0.724,0.724,0.801,0,0,-1.1,1.7
ENSMUSG00000001285,MYG1,melanocyte proliferating gene 1,nucleus|mitochondrion|extracellular vesicular exosome|,locomotory exploration behavior|,molecular_function|,10,-0.2,0.424,10,-0.1,0.469,-0.1,0.71,-0.71,0.803,0,0,-1.5,1.1
ENSMUSG00000032180,TMED1,transmembrane emp24 domain containing 1,endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|plasma membrane|membrane|integral component of membrane|,transport|protein transport|,None,10,0,0,10,0.1,0.961,0.1,0.704,0.704,0.804,0,0,-1.2,1.6
ENSMUSG00000062729,PPOX,protoporphyrinogen oxidase,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|intrinsic component of mitochondrial inner membrane|integral component of mitochondrial inner membrane|mitochondrial membrane|,porphyrin-containing compound biosynthetic process|heme biosynthetic process|heme biosynthetic process|protoporphyrinogen IX metabolic process|oxidation-reduction process|oxidation-reduction process|,oxygen-dependent protoporphyrinogen oxidase activity|oxygen-dependent protoporphyrinogen oxidase activity|oxidoreductase activity|,10,0,0,10,0.3,0.991,0.2,0.699,0.699,0.805,0,0,-1.6,1.4
ENSMUSG00000017688,HNF4G,"hepatocyte nuclear factor 4, gamma",nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|steroid hormone mediated signaling pathway|positive regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.3,1.88,10,0,0,-0.2,0.693,-0.693,0.806,0,0,-1.7,0.8
ENSMUSG00000021596,MCTP1,"multiple C2 domains, transmembrane 1",integral component of membrane|,biological_process|,calcium ion binding|,9,0,0,9,-0.1,0.821,-0.1,0.692,-0.692,0.806,0,0,-1.7,1.2
ENSMUSG00000039321,UTS2R,urotensin 2 receptor,early endosome|plasma membrane|membrane|integral component of membrane|recycling endosome|,"negative regulation of glomerular filtration|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|regulation of blood pressure|positive regulation of circadian sleep/wake cycle, wakefulness|positive regulation of cell growth|negative regulation of urine volume|negative regulation of renal sodium excretion|regulation of vasodilation|positive regulation of angiogenesis|negative regulation of blood pressure|positive regulation of blood pressure|positive regulation of vasoconstriction|positive regulation of circadian sleep/wake cycle, REM sleep|positive regulation of fibroblast proliferation|",urotensin II receptor activity|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0.2,1.52,0.1,0.69,0.69,0.806,0,0,-1.3,1.4
ENSMUSG00000039063,ECHDC3,enoyl Coenzyme A hydratase domain containing 3,mitochondrion|,biological_process|metabolic process|,molecular_function|catalytic activity|,10,0.4,3.2,10,-0.2,0.556,0.3,0.689,0.689,0.806,0,0,-0.9,1.7
ENSMUSG00000026939,TMEM141,transmembrane protein 141,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.96,10,-0.4,0.876,0.2,0.685,0.685,0.807,0,0,-1.4,1.3
ENSMUSG00000042189,TEKT3,tektin 3,acrosomal membrane|nucleus|cytoplasm|cytoskeleton|microtubule|cilium|sperm flagellum|cell projection|extracellular vesicular exosome|,sperm motility|cilium morphogenesis|regulation of fertilization|,None,10,-0.1,0.0432,10,0.2,0.964,0.1,0.674,0.674,0.809,0,0,-1.2,1.4
ENSMUSG00000025909,SNTG1,"syntrophin, gamma 1",nucleus|cytoplasm|cytoskeleton|ruffle membrane|,None,actin binding|protein C-terminus binding|,10,0.1,0.351,10,0.1,0.385,0.1,0.674,0.674,0.809,0,0,-1,1.7
ENSMUSG00000054455,VAPB,"vesicle-associated membrane protein, associated protein B and C",endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|,cellular calcium ion homeostasis|response to unfolded protein|activation of signaling protein activity involved in unfolded protein response|modulation by virus of host morphology or physiology|endoplasmic reticulum unfolded protein response|positive regulation of viral genome replication|,structural molecule activity|enzyme binding|protein homodimerization activity|protein heterodimerization activity|beta-tubulin binding|,10,0.3,1.52,10,0,0,0.2,0.67,0.67,0.809,0,0,-1,1.6
ENSMUSG00000037126,PSD,pleckstrin and Sec7 domain containing,plasma membrane|membrane|integral component of membrane|integral component of membrane|cell junction|cell projection|,neuron differentiation|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|phospholipid binding|,10,-0.3,1.22,10,0.2,1.26,0.1,0.666,0.666,0.81,0,0,-1.7,1.1
ENSMUSG00000033318,GSTT2,"glutathione S-transferase, theta 2",nucleus|cytoplasm|cytosol|,glutathione metabolic process|,glutathione transferase activity|transferase activity|,10,0.2,0.779,10,0.1,0.0772,0.1,0.657,0.657,0.811,0,0,-0.9,1.9
ENSMUSG00000028943,ESPN,espin,cytoplasm|cytoskeleton|microvillus|brush border|brush border|actin cytoskeleton|actin cytoskeleton|cell junction|filamentous actin|stereocilium bundle|stereocilium bundle tip|cell projection|,sensory perception of sound|locomotory behavior|parallel actin filament bundle assembly|actin filament bundle assembly|positive regulation of filopodium assembly|positive regulation of filopodium assembly|negative regulation of cytoskeleton organization|actin filament network formation|,actin binding|protein binding|SH3 domain binding|actin filament binding|,10,0,0,10,0.2,1.32,0.1,0.657,0.657,0.811,0,0,-1.2,1.6
ENSMUSG00000040740,SLC25A34,"solute carrier family 25, member 34",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,9,-0.1,0.109,9,-0.1,0.6,-0.1,0.651,-0.651,0.812,0,0,-1.7,1
ENSMUSG00000055194,ACTBL2,"actin, beta-like 2",extracellular space|cytoplasm|cytoskeleton|extracellular vesicular exosome|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,-0.1,0.378,10,-0.1,0.331,-0.1,0.649,-0.649,0.813,0,0,-1.8,0.9
ENSMUSG00000001349,CNN1,calponin 1,cytoskeleton|,actomyosin structure organization|,actin binding|calmodulin binding|,10,-0.1,0.0571,10,0.1,1.06,0.1,0.649,0.649,0.813,0,0,-1.4,1.4
ENSMUSG00000056494,CNGB3,cyclic nucleotide gated channel beta 3,photoreceptor outer segment|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|transmembrane transporter complex|,"transport|ion transport|cation transport|cation transport|visual perception|phototransduction, visible light|cyclic nucleotide metabolic process|ion transmembrane transport|regulation of ion transmembrane transport|regulation of membrane potential|response to stimulus|transmembrane transport|potassium ion transmembrane transport|",nucleotide binding|ion channel activity|intracellular cAMP activated cation channel activity|intracellular cGMP activated cation channel activity|intracellular cGMP activated cation channel activity|voltage-gated potassium channel activity|protein binding|cGMP binding|cGMP binding|cGMP binding|,10,0.2,1.21,10,0,0,0.2,0.647,0.647,0.813,0,0,-0.7,1.9
ENSMUSG00000032370,LACTB,"lactamase, beta",cytoplasm|mitochondrion|mitochondrion|,None,cysteine-type peptidase activity|hydrolase activity|,10,-0.1,0.61,10,-0.1,0.0924,-0.1,0.646,-0.646,0.813,0,0,-1.7,1
ENSMUSG00000029348,ASPHD2,aspartate beta-hydroxylase domain containing 2,membrane|membrane|integral component of membrane|,biological_process|peptidyl-amino acid modification|oxidation-reduction process|,"sulfonate dioxygenase activity|molecular_function|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.1,0.0244,10,0.2,1.39,0.1,0.635,0.635,0.815,0,0,-1,1.7
ENSMUSG00000025169,OGFOD3,2-oxoglutarate and iron-dependent oxygenase domain containing 3,membrane|membrane|integral component of membrane|extracellular vesicular exosome|,oxidation-reduction process|,"sulfonate dioxygenase activity|molecular_function|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|L-ascorbic acid binding|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0,0,10,0.7,2.21,0.1,0.632,0.632,0.815,0,0,-0.5,2
ENSMUSG00000034593,MYO5A,myosin VA,"ruffle|photoreceptor outer segment|cell|cytoplasm|cytoplasm|cytoplasm|Golgi apparatus|intermediate filament|synaptic vesicle|membrane|myosin complex|secretory granule|secretory granule|axon|insulin-responsive compartment|microtubule plus-end|melanosome|actomyosin|actomyosin, myosin complex part|neuron projection|neuronal cell body|neuronal cell body|","melanin metabolic process|transport|exocytosis|synaptic transmission|visual perception|metabolic process|protein transport|vesicle-mediated transport|regulation of exocytosis|actin filament-based movement|actin filament-based movement|vesicle transport along actin filament|vesicle transport along actin filament|insulin secretion|melanocyte differentiation|regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|locomotion involved in locomotory behavior|secretory granule localization|secretory granule localization|melanosome localization|melanosome transport|melanosome transport|cellular response to insulin stimulus|melanin biosynthetic process|odontogenesis|myelination|anagen|long-chain fatty acid biosynthetic process|pigmentation|pigmentation|developmental pigmentation|synapse organization|neuromuscular process controlling balance|endoplasmic reticulum localization|protein localization to plasma membrane|",microfilament motor activity|microfilament motor activity|SNARE binding|nucleotide binding|motor activity|motor activity|actin binding|calcium ion binding|protein binding|calmodulin binding|ATP binding|syntaxin-1 binding|Rab GTPase binding|ATP-dependent protein binding|poly(A) RNA binding|protein heterodimerization activity|protein dimerization activity|calcium-dependent protein binding|,9,0,0,9,-0.5,2.39,-0.2,0.614,-0.614,0.818,0,0,-1.9,1.1
ENSMUSG00000053483,USP21,ubiquitin specific peptidase 21,nucleus|nucleus|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|ubiquitin-dependent protein catabolic process|chromatin modification|histone deubiquitination|positive regulation of transcription, DNA-templated|",transcription coactivator activity|ubiquitin thiolesterase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|cysteine-type peptidase activity|hydrolase activity|NEDD8-specific protease activity|ubiquitinyl hydrolase activity|metal ion binding|,10,0,0,10,0.1,0.786,0.1,0.605,0.605,0.82,0,0,-1.3,1.5
ENSMUSG00000026602,NPHS2,"nephrosis 2, podocin",plasma membrane|integral component of plasma membrane|cell-cell junction|membrane|integral component of membrane|intrinsic component of the cytoplasmic side of the plasma membrane|intrinsic component of the cytoplasmic side of the plasma membrane|slit diaphragm|slit diaphragm|protein complex|membrane raft|extracellular vesicular exosome|,excretion|actin cytoskeleton reorganization|,protein binding|,10,0,0,10,0.2,0.956,0.1,0.599,0.599,0.821,0,0,-0.9,1.7
ENSMUSG00000032454,RBP2,"retinol binding protein 2, cellular",cytoplasm|cytosol|,retinoid metabolic process|transport|,transporter activity|retinoid binding|lipid binding|retinal binding|retinol binding|,10,0,0,10,0.2,0.955,0.1,0.597,0.597,0.821,0,0,-0.9,1.8
ENSMUSG00000048216,GPR85,G protein-coupled receptor 85,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|intracellular signal transduction|,signal transducer activity|G-protein coupled receptor activity|receptor signaling protein activity|,10,0.3,1.18,10,0,0,0.1,0.589,0.589,0.822,0,0,-1.2,1.6
ENSMUSG00000027457,SNPH,syntaphilin,mitochondrion|cytoplasmic microtubule|plasma membrane|membrane|integral component of membrane|cell junction|mitochondrial membrane|presynaptic membrane|neuron projection|neuronal cell body|synapse|,vesicle fusion|negative regulation of endocytosis|,syntaxin-1 binding|,10,0.5,1.13,10,0,0,0.1,0.588,0.588,0.823,0,0,-0.6,1.9
ENSMUSG00000001100,POLDIP2,"polymerase (DNA-directed), delta interacting protein 2",nucleus|mitochondrion|mitochondrion|mitochondrial nucleoid|,mitochondrion morphogenesis|,"DNA binding|protein binding, bridging|",10,-0.2,1.5,10,-0.7,0.109,-0.3,0.588,-0.588,0.823,0,0,-1.8,0.8
ENSMUSG00000041598,CDC42EP4,CDC42 effector protein (Rho GTPase binding) 4,cytoplasm|cytoskeleton|plasma membrane|actin cytoskeleton|microtubule cytoskeleton|membrane|,Rho protein signal transduction|regulation of cell shape|positive regulation of pseudopodium assembly|,protein binding|poly(A) RNA binding|,10,0.2,0.606,10,-0.2,1.34,-0.1,0.585,-0.585,0.823,0,0,-1.3,1.5
ENSMUSG00000002500,RPL3L,ribosomal protein L3-like,ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|,biological_process|,molecular_function|,10,0.1,0.186,10,0.3,0.752,0.1,0.585,0.585,0.823,0,0,-0.9,1.8
ENSMUSG00000020083,2010107G23RIK,RIKEN cDNA 2010107G23 gene,cellular_component|membrane|integral component of membrane|,biological_process|,protein binding|,10,0,0,10,0.3,1.58,0.2,0.584,0.584,0.823,0,0,-1.1,1.6
ENSMUSG00000062526,MPPE1,metallophosphoesterase 1,cellular_component|Golgi apparatus|membrane|integral component of membrane|,GPI anchor biosynthetic process|transport|biological_process|vesicle-mediated transport|,molecular_function|nuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0.2,1.65,10,-0.1,0.043,0.1,0.578,0.578,0.824,0,0,-1,1.7
ENSMUSG00000072825,CEP170B,centrosomal protein 170B,cellular_component|cytoplasm|cytoskeleton|microtubule|,biological_process|,molecular_function|,9,0.2,0.376,9,0.1,0.266,0.1,0.575,0.575,0.825,0,0,-1.8,1.3
ENSMUSG00000020080,HKDC1,hexokinase domain containing 1,cytosol|,cellular glucose homeostasis|carbohydrate metabolic process|glycolytic process|phosphorylation|carbohydrate phosphorylation|glucose 6-phosphate metabolic process|,"nucleotide binding|glucokinase activity|hexokinase activity|ATP binding|fructokinase activity|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|mannokinase activity|",10,0.3,1.38,10,0,0,0.1,0.57,0.57,0.826,0,0,-1.4,1.5
ENSMUSG00000037669,1110057K04RIK,RIKEN cDNA 1110057K04 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.109,10,-0.5,1.16,-0.2,0.562,-0.562,0.827,0,0,-1.9,0.7
ENSMUSG00000019851,PERP,"PERP, TP53 apoptosis effector",mitochondrion|Golgi apparatus|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|,desmosome organization|apoptotic process|cell adhesion|heterotypic cell-cell adhesion|positive regulation of proteolysis|intrinsic apoptotic signaling pathway by p53 class mediator|amelogenesis|activation of cysteine-type endopeptidase activity|,None,10,-0.2,1.13,10,0.2,0.274,-0.1,0.549,-0.549,0.829,0,0,-1.3,1.5
ENSMUSG00000090110,MTCP1,mature T cell proliferation 1,mitochondrion|mitochondrion|,None,None,7,0.6,2.19,7,0,0,0.2,0.537,0.537,0.831,0,0,-0.7,2
ENSMUSG00000023963,CYP39A1,"cytochrome P450, family 39, subfamily a, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,lipid metabolic process|bile acid biosynthetic process|bile acid biosynthetic process|cholesterol catabolic process|digestion|steroid metabolic process|lipid catabolic process|bile acid catabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|steroid 7-alpha-hydroxylase activity|oxysterol 7-alpha-hydroxylase activity|oxysterol 7-alpha-hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|24-hydroxycholesterol 7alpha-hydroxylase activity|metal ion binding|",10,0,0,10,-0.5,2.96,-0.4,0.529,-0.529,0.833,0,0,-1.9,0.7
ENSMUSG00000061702,TMEM91,transmembrane protein 91,cellular_component|membrane|integral component of membrane|,hematopoietic progenitor cell differentiation|response to biotic stimulus|,molecular_function|,10,0,0,10,-0.2,1.53,-0.1,0.527,-0.527,0.833,0,0,-1.6,1.1
ENSMUSG00000026383,EPB4.1L5,erythrocyte protein band 4.1-like 5,nucleus|cytoplasm|cytoskeleton|plasma membrane|plasma membrane|focal adhesion|extrinsic component of membrane|cell junction|cell leading edge|ruffle membrane|,"cell morphogenesis involved in differentiation|in utero embryonic development|somitogenesis|epithelial to mesenchymal transition|neural plate morphogenesis|positive regulation of cell-matrix adhesion|epithelial cell morphogenesis|apical constriction|substrate-dependent cell migration, cell attachment to substrate|ectoderm development|endoderm development|mesoderm development|mesoderm migration involved in gastrulation|unidimensional cell growth|posttranscriptional regulation of gene expression|positive regulation of epithelial cell migration|positive regulation of epithelial to mesenchymal transition|negative regulation of cell-cell adhesion|actin cytoskeleton organization|actin cytoskeleton organization|actomyosin structure organization|negative regulation of protein binding|positive regulation of protein binding|somite rostral/caudal axis specification|axial mesoderm development|axial mesoderm morphogenesis|paraxial mesoderm development|embryonic foregut morphogenesis|positive regulation of focal adhesion assembly|regulation of establishment of protein localization|left/right axis specification|cellular response to transforming growth factor beta stimulus|",protein binding|cytoskeletal protein binding|protein domain specific binding|,10,0.2,0.966,10,0,0,0.1,0.525,0.525,0.834,0,0,-1.2,1.6
ENSMUSG00000006587,SNAI3,snail family zinc finger 3,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.219,10,-0.3,0.982,0.1,0.521,0.521,0.834,0,0,-1.4,1.4
ENSMUSG00000048096,LMOD1,leiomodin 1 (smooth muscle),cytoplasm|cytoskeleton|,None,molecular_function|actin binding|tropomyosin binding|,10,0.2,0.325,10,0.3,0.253,0.2,0.521,0.521,0.834,0,0,-1.1,1.6
ENSMUSG00000038811,GNGT2,"guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2",heterotrimeric G-protein complex|plasma membrane|membrane|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|,10,-0.1,0.501,10,-0.1,0.0606,-0.1,0.515,-0.515,0.835,0,0,-1.5,1.3
ENSMUSG00000042179,PNLIPRP1,pancreatic lipase related protein 1,extracellular region|extracellular space|,lipid metabolic process|,catalytic activity|triglyceride lipase activity|lipase activity|metal ion binding|,10,0.2,1.26,10,-0.2,0.276,0.1,0.503,0.503,0.837,0,0,-1.3,1.4
ENSMUSG00000025287,ACOT9,acyl-CoA thioesterase 9,mitochondrion|,acyl-CoA metabolic process|,"acetyl-CoA hydrolase activity|protein binding|CoA hydrolase activity|palmitoyl-CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0.5,3.25,10,-0.1,0.352,0.4,0.503,0.503,0.837,0,0,-0.5,1.9
ENSMUSG00000079002,C030006K11RIK,RIKEN cDNA C030006K11 gene,mitochondrion|,biological_process|,molecular_function|,10,0.1,0.00458,10,0.1,0.534,0.1,0.495,0.495,0.839,0,0,-1.5,1.3
ENSMUSG00000023999,KIF6,kinesin family member 6,male germ cell nucleus|microtubule|,None,nucleotide binding|ATP binding|,9,-0.2,0.621,10,-0.1,0.0419,-0.1,0.494,-0.494,0.839,0,0,-1.4,1.5
ENSMUSG00000057315,ARHGAP24,Rho GTPase activating protein 24,intracellular|cytoplasm|cytoskeleton|focal adhesion|cell junction|cell projection|,"angiogenesis|signal transduction|multicellular organismal development|cell differentiation|activation of Rac GTPase activity|negative regulation of Rac protein signal transduction|wound healing, spreading of epidermal cells|negative regulation of ruffle assembly|",GTPase activator activity|Rac GTPase activator activity|,10,-0.1,0.639,10,0,0,-0.1,0.493,-0.493,0.839,0,0,-1.8,1
ENSMUSG00000006219,FBLIM1,filamin binding LIM protein 1,stress fiber|cytoplasm|cytoskeleton|cell junction|,cell adhesion|regulation of cell shape|single organismal cell-cell adhesion|regulation of integrin activation|,zinc ion binding|filamin binding|metal ion binding|,10,0.4,0.85,10,0,0,0.3,0.49,0.49,0.84,0,0,-0.7,1.8
ENSMUSG00000035139,SECISBP2,SECIS binding protein 2,nucleus|mitochondrion|ribonucleoprotein complex|,biological_process|,RNA binding|mRNA 3'-UTR binding|protein binding|selenocysteine insertion sequence binding|ribonucleoprotein complex binding|poly(A) RNA binding|,10,0.1,0.152,10,0.2,0.57,0.1,0.485,0.485,0.841,0,0,-1.2,1.5
ENSMUSG00000052727,MAP1B,microtubule-associated protein 1B,intracellular|cell|cytoplasm|cytosol|cytoskeleton|microtubule|microtubule associated complex|microtubule associated complex|plasma membrane|postsynaptic density|cell junction|axon|dendrite|growth cone|cell projection|neuronal cell body|perikaryon|synapse|perinuclear region of cytoplasm|,microtubule cytoskeleton organization|microtubule bundle formation|microtubule bundle formation|microtubule-based process|negative regulation of microtubule depolymerization|nervous system development|axonogenesis|cellular process|dendrite development|positive regulation of microtubule polymerization|negative regulation of intracellular transport|positive regulation of neuron differentiation|positive regulation of axon extension|positive regulation of axon extension|mitochondrion transport along microtubule|axon extension|establishment of monopolar cell polarity|,actin binding|protein binding|cytoskeletal regulatory protein binding|phospholipid binding|microtubule binding|protein complex binding|,10,0,0,10,0.1,0.659,0.1,0.482,0.482,0.841,0,0,-1.2,1.6
ENSMUSG00000020021,FGD6,"FYVE, RhoGEF and PH domain containing 6",cellular_component|cytoplasm|cytoskeleton|,biological_process|regulation of Rho protein signal transduction|,molecular_function|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|metal ion binding|,10,-0.5,1.65,10,0,0,-0.1,0.48,-0.48,0.841,0,0,-2,0.6
ENSMUSG00000037408,CNNM4,cyclin M4,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|visual perception|biological_process|biomineral tissue development|response to stimulus|,molecular_function|adenyl nucleotide binding|,10,0.2,0.256,10,0.1,0.341,0.1,0.474,0.474,0.842,0,0,-1.7,1.2
ENSMUSG00000022829,STXBP5L,syntaxin binding protein 5-like,cytoplasm|plasma membrane|membrane|integral component of membrane|,transport|exocytosis|protein transport|vesicle-mediated transport|regulation of exocytosis|glucose homeostasis|negative regulation of insulin secretion|positive regulation of protein secretion|,syntaxin binding|,10,0,0,10,-0.2,0.762,-0.1,0.474,-0.474,0.842,0,0,-1.7,1.1
ENSMUSG00000022003,SLC25A30,"solute carrier family 25, member 30",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|transmembrane transport|,molecular_function|,10,0.8,1.33,10,0,0,-0.1,0.474,-0.474,0.842,0,0,-0.7,2
ENSMUSG00000025986,SLC39A10,"solute carrier family 39 (zinc transporter), member 10",cellular_component|membrane|integral component of membrane|,transport|ion transport|zinc ion transport|biological_process|metal ion transport|transmembrane transport|,molecular_function|metal ion transmembrane transporter activity|,10,-0.1,0.548,10,0.3,1.37,0.2,0.468,0.468,0.843,0,0,-1.2,1.5
ENSMUSG00000028919,ARHGEF19,Rho guanine nucleotide exchange factor (GEF) 19,None,positive regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|regulation of Rho protein signal transduction|wound healing|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|,10,-0.2,0.709,10,-0.1,0.0491,-0.1,0.466,-0.466,0.844,0,0,-1.6,1.2
ENSMUSG00000033088,TRIOBP,TRIO and F-actin binding protein,nucleus|cytoplasm|cytoskeleton|actin cytoskeleton|,cell cycle|mitotic nuclear division|cell division|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion-dependent cell spreading|,actin binding|ubiquitin protein ligase binding|actin filament binding|,10,0,0,10,0.1,0.506,0.1,0.464,0.464,0.844,0,0,-1.4,1.5
ENSMUSG00000019996,MAP7,microtubule-associated protein 7,cytoplasm|cytoskeleton|microtubule|plasma membrane|microtubule cytoskeleton|membrane|,microtubule cytoskeleton organization|cell morphogenesis|microtubule bundle formation|glycosphingolipid metabolic process|response to osmotic stress|response to osmotic stress|nucleus organization|germ cell development|spermatogenesis|cell proliferation|fertilization|response to retinoic acid|Leydig cell differentiation|organ growth|homeostasis of number of cells|Sertoli cell development|protein localization to plasma membrane|,receptor binding|protein binding|,10,0,0,10,0.2,0.909,0.1,0.462,0.462,0.844,0,0,-1.2,1.6
ENSMUSG00000090273,PRR22,proline rich 22,cellular_component|,biological_process|,molecular_function|,10,0.4,2.23,10,-0.2,0.604,0.1,0.459,0.459,0.845,0,0,-0.6,2
ENSMUSG00000032579,HEMK1,HemK methyltransferase family member 1,mitochondrion|,protein methylation|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|nucleic acid binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,-0.1,0.036,9,-0.2,0.6,-0.1,0.457,-0.457,0.845,0,0,-1.5,1.4
ENSMUSG00000073609,D2HGDH,D-2-hydroxyglutarate dehydrogenase,mitochondrion|mitochondrion|,response to manganese ion|response to manganese ion|response to zinc ion|response to zinc ion|response to cobalt ion|response to cobalt ion|cellular protein metabolic process|cellular protein metabolic process|oxidation-reduction process|,"catalytic activity|UDP-N-acetylmuramate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|limonene-1,2-diol dehydrogenase activity|flavin adenine dinucleotide binding|(R)-2-hydroxyglutarate dehydrogenase activity|(R)-2-hydroxyglutarate dehydrogenase activity|",10,0,0,10,-0.1,0.519,-0.1,0.455,-0.455,0.846,0,0,-1.7,1.1
ENSMUSG00000038525,ARMC10,armadillo repeat containing 10,mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|regulation of growth|,molecular_function|,10,0,0,10,0.1,0.558,0.1,0.447,0.447,0.847,0,0,-1.1,1.7
ENSMUSG00000028127,ABCD3,"ATP-binding cassette, sub-family D (ALD), member 3",mitochondrion|mitochondrion|mitochondrial inner membrane|peroxisome|peroxisome|peroxisomal membrane|peroxisomal membrane|peroxisomal matrix|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,ATP catabolic process|fatty acid beta-oxidation|transport|peroxisome organization|very long-chain fatty acid catabolic process|transmembrane transport|,"nucleotide binding|protein binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|protein homodimerization activity|protein self-association|",10,0.2,0.095,10,0.1,0.408,0.1,0.445,0.445,0.847,0,0,-1.4,1.4
ENSMUSG00000029179,ZCCHC4,"zinc finger, CCHC domain containing 4",cellular_component|,biological_process|methylation|,nucleic acid binding|methyltransferase activity|zinc ion binding|transferase activity|metal ion binding|,10,0,0,10,0.3,1.91,0.2,0.437,0.437,0.848,0,0,-0.7,1.9
ENSMUSG00000079598,CLEC2L,"C-type lectin domain family 2, member L",cellular_component|membrane|integral component of membrane|,biological_process|,carbohydrate binding|,10,0.2,0.336,10,-0.2,1.57,-0.1,0.432,-0.432,0.849,0,0,-1.7,1.1
ENSMUSG00000032740,CCDC88A,coiled coil domain containing 88A,intracellular|cytoplasm|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|membrane|lamellipodium|cytoplasmic vesicle|cell projection|,regulation of protein phosphorylation|DNA replication|regulation of DNA replication|nervous system development|regulation of neuron projection development|cell migration|lamellipodium assembly|TOR signaling|activation of protein kinase B activity|regulation of actin cytoskeleton organization|regulation of cell proliferation|membrane organization|,actin binding|protein binding|microtubule binding|phosphatidylinositol binding|protein homodimerization activity|protein kinase B binding|protein kinase B binding|,10,0.1,0.188,10,-0.2,1.96,-0.2,0.424,-0.424,0.851,0,0,-1.3,1.5
ENSMUSG00000027350,CHGB,chromogranin B,extracellular region|secretory granule|,None,protein binding|,10,-0.1,0.111,10,0.3,2.29,0.2,0.419,0.419,0.852,0,0,-0.8,1.8
ENSMUSG00000000340,DBT,dihydrolipoamide branched chain transacylase E2,mitochondrion|mitochondrion|mitochondrial nucleoid|,metabolic process|,"transferase activity|transferase activity, transferring acyl groups|dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity|",10,-0.2,0.734,10,0,0,-0.1,0.41,-0.41,0.853,0,0,-1.5,1.3
ENSMUSG00000075700,SELT,selenoprotein T,cell|endoplasmic reticulum|,response to glucose|pancreas development|insulin secretion involved in cellular response to glucose stimulus|glucose homeostasis|cell redox homeostasis|,selenium binding|,10,-0.1,0.314,10,-0.1,0.131,-0.1,0.406,-0.406,0.854,0,0,-1.6,1.2
ENSMUSG00000029154,CWH43,cell wall biogenesis 43 C-terminal homolog (S. cerevisiae),cellular_component|membrane|integral component of membrane|,GPI anchor biosynthetic process|biological_process|,molecular_function|,10,0.2,0.877,10,0,0,0.1,0.404,0.404,0.854,0,0,-0.8,1.9
ENSMUSG00000030986,DHX32,DEAH (Asp-Glu-Ala-His) box polypeptide 32,cellular_component|nucleus|mitochondrion|,biological_process|,nucleotide binding|molecular_function|helicase activity|ATP binding|hydrolase activity|,10,0,0,10,-0.6,0.94,0.1,0.402,0.402,0.855,0,0,-2,0.8
ENSMUSG00000020620,ABCA8B,"ATP-binding cassette, sub-family A (ABC1), member 8b",mitochondrial inner membrane|plasma membrane|membrane|integral component of membrane|,ATP catabolic process|transport|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,0,0,10,0.2,1.1,0.1,0.4,0.4,0.855,0,0,-1.1,1.7
ENSMUSG00000054894,ATP5S,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit S","mitochondrion|mitochondrial inner membrane|membrane|proton-transporting ATP synthase complex, coupling factor F(o)|",ATP biosynthetic process|transport|ion transport|proton transport|,metal ion binding|,9,0,0,9,0.1,0.532,0.1,0.397,0.397,0.856,0,0,-1.3,1.6
ENSMUSG00000024510,FTMT,ferritin mitochondrial,nucleus|mitochondrion|mitochondrion|,iron ion transport|cellular iron ion homeostasis|cellular iron ion homeostasis|positive regulation of cell proliferation|positive regulation of transferase activity|positive regulation of lyase activity|positive regulation of oxidoreductase activity|oxidation-reduction process|,ferroxidase activity|iron ion binding|ferric iron binding|oxidoreductase activity|metal ion binding|,10,-0.1,0.102,10,-0.2,0.698,-0.1,0.393,-0.393,0.856,0,0,-1.6,1.1
ENSMUSG00000036985,ZDHHC9,"zinc finger, DHHC domain containing 9",palmitoyltransferase complex|cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|intrinsic component of Golgi membrane|,peptidyl-L-cysteine S-palmitoylation|protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|Ras palmitoyltransferase activity|metal ion binding|",10,0,0,10,0.1,0.725,0.1,0.387,0.387,0.857,0,0,-1.1,1.7
ENSMUSG00000033917,GDE1,glycerophosphodiester phosphodiesterase 1,cytoplasm|integral component of plasma membrane|membrane|integral component of membrane|,glycerol metabolic process|lipid metabolic process|G-protein coupled receptor signaling pathway|,phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|metal ion binding|glycerophosphoinositol glycerophosphodiesterase activity|,9,-0.1,0.0265,9,-0.1,0.389,-0.1,0.381,-0.381,0.858,0,0,-1.1,1.9
ENSMUSG00000021432,SLC35B3,"solute carrier family 35, member B3",mitochondrion|Golgi apparatus|membrane|integral component of membrane|,transport|transmembrane transport|,None,10,-0.2,2.31,10,-1.1,1.12,-0.2,0.378,-0.378,0.859,0,0,-2,0.3
ENSMUSG00000030554,SYNM,"synemin, intermediate filament protein",cytoplasm|cytoskeleton|intermediate filament|adherens junction|membrane|Z disc|cell junction|costamere|neurofilament cytoskeleton|,biological_process|,"structural molecule activity|structural constituent of cytoskeleton|protein binding|structural constituent of muscle|vinculin binding|intermediate filament binding|protein binding, bridging|",10,0,0,10,-0.3,1.16,-0.1,0.376,-0.376,0.859,0,0,-1.5,1.2
ENSMUSG00000025656,ARHGEF9,CDC42 guanine nucleotide exchange factor (GEF) 9,cytoplasm|cell cortex|cell cortex|,small GTPase mediated signal transduction|regulation of Rho protein signal transduction|receptor clustering|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0,0,10,0.1,1.08,0.1,0.374,0.374,0.86,0,0,-1.1,1.7
ENSMUSG00000041444,ARHGAP32,Rho GTPase activating protein 32,intracellular|cytoplasm|endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|cell cortex|actin cytoskeleton|membrane|cell junction|cell projection|synapse|postsynaptic membrane|,signal transduction|Rho protein signal transduction|positive regulation of GTPase activity|,GTPase activator activity|phosphatidylinositol binding|,10,0,0,10,0.4,1.04,0.3,0.364,0.364,0.861,0,0,-0.9,1.8
ENSMUSG00000015355,CD48,CD48 antigen,plasma membrane|external side of plasma membrane|membrane|membrane|integral component of membrane|anchored component of membrane|protein complex|membrane raft|anchored component of plasma membrane|extracellular vesicular exosome|,signal transduction|T cell activation|mast cell activation|,antigen binding|receptor activity|protein binding|,10,-0.1,0.182,10,-0.1,0.215,-0.1,0.362,-0.362,0.861,0,0,-1.1,1.8
ENSMUSG00000030276,TTLL3,"tubulin tyrosine ligase-like family, member 3",cytoplasm|cytoskeleton|microtubule|cilium|axoneme|microtubule cytoskeleton|cell projection|,cellular protein modification process|protein polyglycylation|protein polyglycylation|cilium assembly|,"UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.673,10,-0.1,0.943,-0.1,0.359,-0.359,0.862,0,0,-1,1.6
ENSMUSG00000029263,PIGG,"phosphatidylinositol glycan anchor biosynthesis, class G",endoplasmic reticulum|membrane|,GPI anchor biosynthetic process|,CP2 mannose-ethanolamine phosphotransferase activity|,10,0,0,10,0.1,0.409,0.1,0.352,0.352,0.863,0,0,-1.4,1.5
ENSMUSG00000032026,REXO2,"REX2, RNA exonuclease 2 homolog (S. cerevisiae)",nucleus|nucleolus|mitochondrion|mitochondrion|focal adhesion|,nucleobase-containing compound metabolic process|nucleic acid phosphodiester bond hydrolysis|nucleic acid phosphodiester bond hydrolysis|,"nucleic acid binding|nuclease activity|exonuclease activity|3'-5' exonuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|",10,0,0,10,-0.1,0.398,-0.1,0.35,-0.35,0.863,0,0,-1.5,1.3
ENSMUSG00000048424,RANBP3L,RAN binding protein 3-like,cellular_component|,biological_process|intracellular transport|,molecular_function|,10,0,0,10,0.2,1.4,0.1,0.347,0.347,0.864,0,0,-1,1.7
ENSMUSG00000031202,RAB39B,"RAB39B, member RAS oncogene family",intracellular|Golgi apparatus|Golgi apparatus|plasma membrane|membrane|,transport|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|synapse organization|,nucleotide binding|GTP binding|,10,0.3,1.61,10,0,0,0.1,0.345,0.345,0.864,0,0,-1.2,1.5
ENSMUSG00000025380,FSCN2,"fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)",cytoplasm|cytoskeleton|actin cytoskeleton|stereocilium|cell projection|,eye photoreceptor cell development|,"actin binding|protein binding, bridging|actin filament binding|",10,-0.3,1.21,10,0,0,-0.1,0.345,-0.345,0.864,0,0,-1.9,0.8
ENSMUSG00000003484,CYP4F18,"cytochrome P450, family 4, subfamily f, polypeptide 18",cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|apical plasma membrane|intracellular membrane-bounded organelle|,very long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|regulation of blood pressure|drug metabolic process|arachidonic acid metabolic process|epoxygenase P450 pathway|negative regulation of blood coagulation|negative regulation of icosanoid secretion|positive regulation of icosanoid secretion|leukotriene B4 catabolic process|vitamin E metabolic process|vitamin K biosynthetic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|arachidonic acid epoxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|alkane 1-monooxygenase activity|heme binding|metal ion binding|vitamin-K-epoxide reductase (warfarin-sensitive) activity|leukotriene-B4 20-monooxygenase activity|arachidonic acid omega-hydroxylase activity|tocopherol omega-hydroxylase activity|alpha-tocopherol omega-hydroxylase activity|tocotrienol omega-hydroxylase activity|",10,0.2,0.642,10,0,0,0.1,0.344,0.344,0.864,0,0,-0.9,1.9
ENSMUSG00000022100,XPO7,exportin 7,intracellular|cell|nucleus|nuclear pore|cytoplasm|,protein export from nucleus|transport|intracellular protein transport|nucleocytoplasmic transport|protein transport|mRNA transport|,nuclear export signal receptor activity|protein binding|Ran GTPase binding|,10,0,0,10,-1,1.89,0.1,0.337,0.337,0.866,0,0,-2,0.7
ENSMUSG00000041028,GHITM,growth hormone inducible transmembrane protein,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|extracellular vesicular exosome|,apoptotic process|,None,10,-0.1,0.578,10,0,0,-0.1,0.332,-0.332,0.867,0,0,-1.7,1.1
ENSMUSG00000029729,ZKSCAN1,zinc finger with KRAB and SCAN domains 1,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0.2,0.665,0.1,0.325,0.325,0.868,0,0,-1,1.7
ENSMUSG00000040797,IQSEC3,IQ motif and Sec7 domain 3,nucleus|cytoplasm|cell junction|postsynaptic membrane|inhibitory synapse|,actin cytoskeleton organization|regulation of ARF protein signal transduction|activation of ARF GTPase activity|positive regulation of GTPase activity|regulation of small GTPase mediated signal transduction|,ARF guanyl-nucleotide exchange factor activity|protein binding|,10,0.2,1.66,10,0,0,0.1,0.323,0.323,0.868,0,0,-1,1.7
ENSMUSG00000051439,CD14,CD14 antigen,extracellular space|plasma membrane|cell surface|membrane|anchored component of membrane|membrane raft|extracellular vesicular exosome|,response to molecule of bacterial origin|immune system process|inflammatory response|positive regulation of tumor necrosis factor production|response to tumor necrosis factor|innate immune response|positive regulation of endocytosis|positive regulation of cytokine secretion|cellular response to lipopolysaccharide|cellular response to lipoteichoic acid|,lipopolysaccharide binding|lipoteichoic acid binding|,10,0.2,1.69,10,-0.3,0.652,0.1,0.322,0.322,0.868,0,0,-1.2,1.6
ENSMUSG00000058997,VWA8,von Willebrand factor A domain containing 8,extracellular region|mitochondrion|,biological_process|,nucleotide binding|molecular_function|ATP binding|ATPase activity|,10,-0.1,0.139,10,-0.1,0.213,-0.1,0.32,-0.32,0.869,0,0,-1.3,1.6
ENSMUSG00000017588,KRT27,keratin 27,cytoplasm|intermediate filament|,hair follicle morphogenesis|,structural molecule activity|,10,0.5,1.62,10,0.1,0.107,0.3,0.32,0.32,0.869,0,0,-0.6,1.9
ENSMUSG00000032531,AMOTL2,angiomotin-like 2,intracellular|endosome|tight junction|apical plasma membrane|cytoplasmic vesicle|,Wnt signaling pathway|hippo signaling|,protein binding|identical protein binding|,10,-0.1,0.273,10,0.3,1.9,0.2,0.319,0.319,0.869,0,0,-1.5,1.4
ENSMUSG00000057778,CYB5D2,cytochrome b5 domain containing 2,extracellular region|,nervous system development|positive regulation of neuron differentiation|,heme binding|,10,0,0,10,0.1,0.519,0.1,0.316,0.316,0.869,0,0,-1.1,1.8
ENSMUSG00000043485,KRT34,keratin 34,extracellular space|intermediate filament|extracellular vesicular exosome|,None,structural molecule activity|,10,0.3,1.13,10,-0.5,1.23,0.1,0.311,0.311,0.87,0,0,-1.8,1.1
ENSMUSG00000014245,PIGL,"phosphatidylinositol glycan anchor biosynthesis, class L",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,GPI anchor biosynthetic process|,N-acetylglucosaminylphosphatidylinositol deacetylase activity|hydrolase activity|,10,-0.1,0.52,10,0.1,0.721,-0.1,0.308,-0.308,0.871,0,0,-1.4,1.4
ENSMUSG00000025421,HDHD2,haloacid dehalogenase-like hydrolase domain containing 2,extracellular vesicular exosome|,None,enzyme binding|metal ion binding|,10,0.2,0.31,10,-0.1,0.35,-0.1,0.307,-0.307,0.871,0,0,-1.6,1.3
ENSMUSG00000070570,SLC17A7,"solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7",synaptic vesicle|membrane|integral component of membrane|cell junction|synaptic vesicle membrane|cytoplasmic vesicle|neuron projection|intracellular organelle|cerebellar mossy fiber|synapse|synapse|presynaptic active zone|excitatory synapse|excitatory synapse|,"transport|ion transport|sodium ion transport|phosphate ion transport|neurotransmitter transport|synaptic transmission|long-term memory|synaptic transmission, glutamatergic|phosphate ion transmembrane transport|sodium ion transmembrane transport|sequestering of neurotransmitter|sodium-dependent phosphate transport|response to stimulus|L-glutamate import|L-glutamate import|L-glutamate import|transmembrane transport|regulation of excitatory postsynaptic membrane potential|",inorganic phosphate transmembrane transporter activity|symporter activity|sodium:inorganic phosphate symporter activity|sodium-dependent phosphate transmembrane transporter activity|,10,0,0,10,0.3,0.928,0.1,0.302,0.302,0.872,0,0,-1.1,1.7
ENSMUSG00000030495,SLC7A10,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 10",integral component of plasma membrane|membrane|integral component of membrane|dendrite|,amino acid transmembrane transport|transport|amino acid transport|neutral amino acid transport|neutral amino acid transport|D-alanine transport|D-serine transport|,protein binding|amino acid transmembrane transporter activity|neutral amino acid transmembrane transporter activity|neutral amino acid transmembrane transporter activity|,10,0,0,10,0.1,0.457,0.1,0.299,0.299,0.872,0,0,-1,1.8
ENSMUSG00000018858,ICT1,immature colon carcinoma transcript 1,mitochondrion|mitochondrion|mitochondrial large ribosomal subunit|,translation|translational termination|mitochondrial translational termination|,"translation release factor activity|aminoacyl-tRNA hydrolase activity|translation release factor activity, codon nonspecific|hydrolase activity|",10,0.1,0.109,10,-0.1,0.487,-0.1,0.298,-0.298,0.872,0,0,-1.6,1.2
ENSMUSG00000047766,LRRC49,leucine rich repeat containing 49,cellular_component|cytoplasm|cytoskeleton|microtubule|,biological_process|,molecular_function|,10,0.8,0.0311,10,0.1,0.692,0.1,0.296,0.296,0.873,0,0,-0.6,2
ENSMUSG00000029208,GUF1,GUF1 GTPase homolog (S. cerevisiae),mitochondrion|mitochondrial inner membrane|membrane|,translation|biological_process|,nucleotide binding|GTPase activity|GTP binding|hydrolase activity|,10,-0.1,1.15,10,0.1,1.18,-0.1,0.293,-0.293,0.873,0,0,-1.5,1.3
ENSMUSG00000034958,ATCAY,"ataxia, cerebellar, Cayman type homolog (human)",cytoplasm|mitochondrion|cell junction|axon|dendrite|mitochondrial membrane|cell projection|neuron projection|neuron projection|synapse|,transport|apoptotic process|nervous system development|neuron projection development|neuron projection development|regulation of protein localization|mitochondrion distribution|negative regulation of glutamate metabolic process|,kinesin binding|,10,-0.2,0.773,10,0.2,0.984,0.1,0.288,0.288,0.874,0,0,-1.3,1.5
ENSMUSG00000017721,PIGT,"phosphatidylinositol glycan anchor biosynthesis, class T",cytoplasm|endoplasmic reticulum|membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|GPI-anchor transamidase complex|,GPI anchor biosynthetic process|attachment of GPI anchor to protein|neuron differentiation|neuron apoptotic process|,GPI-anchor transamidase activity|,10,-0.1,0.00707,10,-0.6,1.02,-0.2,0.286,-0.286,0.874,0,0,-2,0.6
ENSMUSG00000026155,SMAP1,small ArfGAP 1,cytoplasm|plasma membrane|membrane|,regulation of ARF GTPase activity|positive regulation of GTPase activity|positive regulation of erythrocyte differentiation|regulation of clathrin-mediated endocytosis|,GTPase activator activity|ARF GTPase activator activity|zinc ion binding|clathrin binding|metal ion binding|,10,1.5,1.49,10,-0.9,3.37,-0.2,0.286,-0.286,0.874,0,0,-2,2.4
ENSMUSG00000041199,RPUSD1,RNA pseudouridylate synthase domain containing 1,cellular_component|,pseudouridine synthesis|RNA modification|,RNA binding|pseudouridine synthase activity|,10,-0.1,0.13,10,0.2,0.487,0.1,0.282,0.282,0.875,0,0,-1.1,1.6
ENSMUSG00000056515,RAB31,"RAB31, member RAS oncogene family",endosome|early endosome|early endosome|late endosome|Golgi apparatus|trans-Golgi network|membrane|cytoplasmic vesicle|trans-Golgi network membrane|phagocytic vesicle|,small GTPase mediated signal transduction|protein transport|receptor internalization|cellular response to insulin stimulus|Golgi to plasma membrane protein transport|regulated secretory pathway|Golgi vesicle transport|phagosome maturation|,nucleotide binding|GTP binding|GDP binding|,9,-0.6,1.46,9,0.1,0.771,0.1,0.281,0.281,0.875,0,0,-2,0.9
ENSMUSG00000020788,ATP2A3,"ATPase, Ca++ transporting, ubiquitous",nucleus|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|sarcoplasmic reticulum|,ATP catabolic process|transport|ion transport|cation transport|calcium ion transport|calcium ion transmembrane transport|,nucleotide binding|calcium-transporting ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,0,0,10,0.2,1.2,0.1,0.28,0.28,0.875,0,0,-0.9,1.8
ENSMUSG00000033475,TOMM6,translocase of outer mitochondrial membrane 6 homolog (yeast),mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane translocase complex|membrane|,transport|biological_process|protein transport|,molecular_function|,10,0,0,10,-0.1,0.507,-0.1,0.274,-0.274,0.876,0,0,-1.4,1.5
ENSMUSG00000028369,SVEP1,"sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1",extracellular region|cytoplasm|membrane|,cell adhesion|biological_process|,chromatin binding|calcium ion binding|,10,0,0,10,-0.2,1.26,-0.1,0.27,-0.27,0.877,0,0,-1.5,1.3
ENSMUSG00000037161,MGARP,mitochondria localized glutamic acid rich protein,intracellular|cell|mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|,protein targeting to mitochondrion|anterograde axon cargo transport|retrograde axon cargo transport|positive regulation of mitochondrion organization|axon transport of mitochondrion|cellular response to steroid hormone stimulus|cellular response to hypoxia|cellular response to gonadotropin-releasing hormone|,protein binding|,10,0.2,0.318,10,-0.1,0.376,0.1,0.265,0.265,0.878,0,0,-1.2,1.5
ENSMUSG00000034574,DAAM1,dishevelled associated activator of morphogenesis 1,stress fiber|stress fiber|cytoplasm|plasma membrane|membrane|,cellular component organization|actin cytoskeleton organization|,actin binding|protein binding|Rho GTPase binding|identical protein binding|,10,0.2,0.99,10,0,0,0.1,0.261,0.261,0.879,0,0,-1.1,1.7
ENSMUSG00000026669,MCM10,minichromosome maintenance deficient 10 (S. cerevisiae),nucleus|nucleolus|cytoplasm|,DNA replication|cell proliferation|,DNA binding|identical protein binding|metal ion binding|,10,0,0,10,0.1,0.439,0.1,0.258,0.258,0.879,0,0,-1.1,1.7
ENSMUSG00000042686,JPH1,junctophilin 1,endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|junctional sarcoplasmic reticulum membrane|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|Z disc|junctional membrane complex|,muscle organ development|,structural constituent of muscle|,10,0,0,10,-0.1,0.488,-0.1,0.25,-0.25,0.881,0,0,-1.7,1.2
ENSMUSG00000020903,STX8,syntaxin 8,lysosomal membrane|membrane|integral component of membrane|SNARE complex|SNARE complex|late endosome membrane|,transport|intracellular protein transport|vesicle fusion|vesicle fusion|endosome to lysosome transport|vesicle-mediated transport|,SNARE binding|SNAP receptor activity|ubiquitin protein ligase binding|,10,0.2,0.545,10,0,0,0.1,0.244,0.244,0.882,0,0,-1.1,1.7
ENSMUSG00000015092,EDF1,endothelial differentiation-related factor 1,nucleus|transcription factor TFIID complex|nucleolus|cytoplasm|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell differentiation|positive regulation of DNA binding|regulation of RNA biosynthetic process|",DNA binding|transcription coactivator activity|calmodulin binding|sequence-specific DNA binding|poly(A) RNA binding|,10,-0.1,0.205,10,0.4,0.805,0.4,0.243,0.243,0.882,0,0,-0.7,1.9
ENSMUSG00000051879,KRT71,keratin 71,intermediate filament|keratin filament|,cytoskeleton organization|hair follicle morphogenesis|,structural molecule activity|structural constituent of cytoskeleton|,10,-0.2,1.88,10,0,0,-0.1,0.24,-0.24,0.882,0,0,-1.7,1
ENSMUSG00000042289,HSD3B7,"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,regulation of cell growth|steroid biosynthetic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|3-beta-hydroxy-delta5-steroid dehydrogenase activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",9,0,0,9,0.1,0.312,0.1,0.24,0.24,0.882,0,0,-1,1.9
ENSMUSG00000027508,PAG1,phosphoprotein associated with glycosphingolipid microdomains 1,intracellular|plasma membrane|plasma membrane|membrane|integral component of membrane|membrane raft|membrane raft|,immune system process|intracellular signal transduction|intracellular signal transduction|regulation of T cell activation|regulation of T cell activation|negative regulation of T cell activation|,protein binding|SH2 domain binding|,10,0,0,10,-0.5,1.24,-0.1,0.235,-0.235,0.883,0,0,-2,0.7
ENSMUSG00000030972,ACSM5,acyl-CoA synthetase medium-chain family member 5,cellular_component|mitochondrion|,lipid metabolic process|fatty acid metabolic process|biological_process|metabolic process|,nucleotide binding|molecular_function|catalytic activity|ATP binding|ligase activity|metal ion binding|butyrate-CoA ligase activity|,10,-0.1,0.154,10,0.1,0.904,0.1,0.228,0.228,0.885,0,0,-1.4,1.4
ENSMUSG00000025971,9430016H08RIK,RIKEN cDNA 9430016H08 gene,cellular_component|mitochondrion|,biological_process|,molecular_function|,10,0,0,10,0.2,1.12,0.1,0.227,0.227,0.885,0,0,-1.4,1.3
ENSMUSG00000030905,CRYM,"crystallin, mu",nucleus|cytoplasm|mitochondrion|cytosol|extracellular vesicular exosome|,negative regulation of transcription from RNA polymerase II promoter|mitochondrial transport|sensory perception of sound|thyroid hormone metabolic process|oxidation-reduction process|thyroid hormone transport|,transcription corepressor activity|oxidoreductase activity|hormone binding|protein homodimerization activity|thiomorpholine-carboxylate dehydrogenase activity|NADP binding|thyroid hormone binding|,10,0,0,10,0.2,0.821,0.1,0.223,0.223,0.886,0,0,-1.2,1.7
ENSMUSG00000039886,TMEM120A,transmembrane protein 120A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.405,-0.1,0.22,-0.22,0.886,0,0,-1.8,1
ENSMUSG00000045288,USH1G,Usher syndrome 1G,cytoplasm|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|,sensory perception of sound|sensory perception of sound|inner ear morphogenesis|photoreceptor cell maintenance|sensory perception of light stimulus|equilibrioception|inner ear receptor cell differentiation|,protein binding|spectrin binding|protein homodimerization activity|,10,0.3,1.92,10,-0.1,0.263,0.2,0.214,0.214,0.887,0,0,-1.5,1.3
ENSMUSG00000063296,TMEM117,transmembrane protein 117,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.38,10,0,0,-0.1,0.212,-0.212,0.888,0,0,-1.8,0.9
ENSMUSG00000039585,MYO9A,myosin IXa,intracellular|membrane|integral component of membrane|myosin complex|,signal transduction|intracellular signal transduction|positive regulation of GTPase activity|,nucleotide binding|motor activity|actin binding|GTPase activator activity|ATP binding|metal ion binding|,10,0.2,0.0111,10,0.1,0.336,0.1,0.209,0.209,0.888,0,0,-0.9,1.9
ENSMUSG00000029581,FSCN1,"fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)",stress fiber|ruffle|cytoplasm|cytoskeleton|plasma membrane|microvillus|actin cytoskeleton|lamellipodium|cell junction|filopodium|filopodium|dendrite|growth cone|cell projection|extracellular vesicular exosome|invadopodium|,cell migration|cell migration|actin cytoskeleton organization|cell motility|actin filament bundle assembly|actin filament bundle assembly|,"actin binding|protein binding|drug binding|drug binding|protein binding, bridging|poly(A) RNA binding|actin filament binding|actin filament binding|",10,0.2,0.434,10,-0.1,0.204,0.1,0.203,0.203,0.889,0,0,-1.2,1.7
ENSMUSG00000025141,MYADML2,myeloid-associated differentiation marker-like 2,cytoplasm|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.195,10,-0.1,0.416,-0.1,0.2,-0.2,0.89,0,0,-1.6,1.2
ENSMUSG00000090399,NAV1,neuron navigator 1,cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|,microtubule bundle formation|neuron migration|multicellular organismal development|nervous system development|cell differentiation|,nucleotide binding|ATP binding|,10,0,0,10,0.2,0.315,0.2,0.194,0.194,0.891,0,0,-0.6,2
ENSMUSG00000061306,SLC38A10,"solute carrier family 38, member 10",Golgi apparatus|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|amino acid transport|bone development|,molecular_function|,10,0.3,0.606,10,0,0,0.1,0.193,0.193,0.891,0,0,-1.8,1.1
ENSMUSG00000028167,BDH2,"3-hydroxybutyrate dehydrogenase, type 2",cytoplasm|extracellular vesicular exosome|,fatty acid beta-oxidation|metabolic process|siderophore biosynthetic process|epithelial cell differentiation|iron ion homeostasis|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|3-hydroxybutyrate dehydrogenase activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|NAD binding|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,-0.1,0.00257,10,0.1,0.657,0.1,0.185,0.185,0.892,0,0,-1.4,1.4
ENSMUSG00000061322,DNAIC1,"dynein, axonemal, intermediate chain 1",cytoplasm|cytoskeleton|microtubule|cilium|dynein complex|cell projection|,epithelial cilium movement|,motor activity|,10,0,0,10,0.1,0.259,0.1,0.185,0.185,0.892,0,0,-1.2,1.7
ENSMUSG00000026255,EFHD1,EF hand domain containing 1,mitochondrion|mitochondrial inner membrane|extracellular vesicular exosome|,neuron projection development|,calcium ion binding|metal ion binding|,10,0,0,10,0.2,0.813,0.1,0.181,0.181,0.893,0,0,-1.6,1.3
ENSMUSG00000035151,ELMOD2,ELMO/CED-12 domain containing 2,cytoskeleton|membrane|,phagocytosis|positive regulation of GTPase activity|regulation of defense response to virus|,GTPase activator activity|,10,0,0,10,0.1,0.666,0.1,0.179,0.179,0.893,0,0,-1.5,1.3
ENSMUSG00000004892,BCAN,brevican,extracellular region|proteinaceous extracellular matrix|extracellular space|dendrite|anchored component of membrane|synapse|,cell adhesion|hippocampus development|,hyaluronic acid binding|carbohydrate binding|,10,0,0,10,-0.1,0.223,-0.1,0.177,-0.177,0.893,0,0,-1.7,1.1
ENSMUSG00000039232,STX11,syntaxin 11,cell|Golgi apparatus|membrane|,T cell mediated cytotoxicity|transport|intracellular protein transport|protein transport|vesicle-mediated transport|natural killer cell mediated cytotoxicity|neutrophil degranulation|cytotoxic T cell degranulation|natural killer cell degranulation|,SNAP receptor activity|,10,0,0,10,-0.1,0.327,-0.1,0.172,-0.172,0.894,0,0,-1.7,1.2
ENSMUSG00000025645,CCDC51,coiled-coil domain containing 51,nucleus|mitochondrion|mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0,0,10,-0.1,0.44,-0.1,0.168,-0.168,0.895,0,0,-1.7,1.2
ENSMUSG00000043157,ARL11,ADP-ribosylation factor-like 11,cellular_component|intracellular|,hematopoietic progenitor cell differentiation|small GTPase mediated signal transduction|,nucleotide binding|GTP binding|,10,0,0,10,0.2,0.99,0.1,0.168,0.168,0.895,0,0,-0.9,1.9
ENSMUSG00000039519,CYP7B1,"cytochrome P450, family 7, subfamily b, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,lipid metabolic process|bile acid biosynthetic process|digestion|memory|circadian rhythm|steroid metabolic process|cholesterol metabolic process|negative regulation of intracellular estrogen receptor signaling pathway|positive regulation of epithelial cell proliferation|oxidation-reduction process|prostate gland epithelium morphogenesis|,"monooxygenase activity|iron ion binding|oxysterol 7-alpha-hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|25-hydroxycholesterol 7alpha-hydroxylase activity|metal ion binding|",10,0,0,10,-0.1,0.535,-0.1,0.164,-0.164,0.895,0,0,-1.5,1.4
ENSMUSG00000022223,SDR39U1,"short chain dehydrogenase/reductase family 39U, member 1",nucleus|,biological_process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|molecular_function|catalytic activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|coenzyme binding|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.1,0.112,10,0.1,0.0568,0.1,0.153,0.153,0.897,0,0,-1,1.8
ENSMUSG00000030086,CHCHD6,coiled-coil-helix-coiled-coil-helix domain containing 6,mitochondrion|mitochondrial inner membrane|membrane|,cellular response to DNA damage stimulus|cristae formation|,molecular_function|,10,-0.2,0.877,10,0.8,2.93,-0.1,0.153,-0.153,0.897,0,0,-0.7,2
ENSMUSG00000016495,PLGRKT,"plasminogen receptor, C-terminal lysine transmembrane protein",mitochondrion|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,chemotaxis|inflammatory response|positive regulation of plasminogen activation|,protein binding|,10,0,0,10,-0.5,1.51,0.1,0.151,0.151,0.897,0,0,-1.9,0.9
ENSMUSG00000020514,MRPL22,mitochondrial ribosomal protein L22,mitochondrion|ribosome|large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,0.2,0.802,10,-0.1,0.941,0.1,0.151,0.151,0.897,0,0,-0.9,1.8
ENSMUSG00000026755,ARPC5L,"actin related protein 2/3 complex, subunit 5-like",cytoplasm|cytoskeleton|extracellular vesicular exosome|,biological_process|regulation of actin filament polymerization|,molecular_function|actin binding|,10,-0.1,0.211,10,0,0,-0.1,0.15,-0.15,0.898,0,0,-1.8,1.1
ENSMUSG00000052396,MOGAT2,monoacylglycerol O-acyltransferase 2,endoplasmic reticulum|membrane|integral component of membrane|,glycerol metabolic process|lipid metabolic process|diacylglycerol biosynthetic process|triglyceride biosynthetic process|monoacylglycerol metabolic process|intestinal absorption|,"2-acylglycerol O-acyltransferase activity|2-acylglycerol O-acyltransferase activity|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|",10,0,0,10,-0.1,0.285,-0.1,0.141,-0.141,0.899,0,0,-1.9,1
ENSMUSG00000051998,LAX1,lymphocyte transmembrane adaptor 1,cell|cytoplasm|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|,inactivation of MAPK activity|immune system process|immune response|intracellular signal transduction|B cell activation|lymphocyte activation|immunoglobulin secretion|antigen receptor-mediated signaling pathway|negative regulation of T cell activation|,protein kinase binding|SH2 domain binding|,10,0.1,0.14,10,-0.1,0.125,-0.1,0.137,-0.137,0.9,0,0,-1.5,1.3
ENSMUSG00000075402,KRT76,keratin 76,nucleus|intermediate filament|keratin filament|,biological_process|,molecular_function|structural molecule activity|,10,0,0,10,-0.2,1.07,-0.2,0.133,-0.133,0.901,0,0,-1.7,1.1
ENSMUSG00000024592,C330018D20RIK,RIKEN cDNA C330018D20 gene,mitochondrion|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,-0.1,0.377,10,0.1,0.57,-0.1,0.132,-0.132,0.901,0,0,-1.5,1.3
ENSMUSG00000026096,OSGEPL1,O-sialoglycoprotein endopeptidase-like 1,mitochondrion|,tRNA processing|,"transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,0,0,10,0.3,0.987,0.1,0.129,0.129,0.901,0,0,-1.2,1.6
ENSMUSG00000020238,NCLN,nicalin homolog (zebrafish),endoplasmic reticulum|membrane|membrane|integral component of membrane|,biological_process|regulation of signal transduction|,molecular_function|,10,-0.8,1.33,10,0,0,0.1,0.128,0.128,0.901,0,0,-2,1
ENSMUSG00000004394,TMED4,transmembrane emp24 protein transport domain containing 4,endoplasmic reticulum|membrane|integral component of membrane|extracellular vesicular exosome|,transport|signal transduction|protein transport|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|,10,-0.2,1.41,10,0,0,-0.1,0.126,-0.126,0.902,0,0,-1.8,1
ENSMUSG00000026047,KDELC1,KDEL (Lys-Asp-Glu-Leu) containing 1,endoplasmic reticulum|endoplasmic reticulum lumen|,None,None,10,0.3,1.3,10,0,0,0.1,0.125,0.125,0.902,0,0,-0.7,2
ENSMUSG00000031889,D230025D16RIK,RIKEN cDNA D230025D16 gene,trans-Golgi network|membrane|dendrite|synaptic vesicle membrane|,Golgi to plasma membrane protein transport|,receptor binding|glutamate receptor binding|,10,-0.1,0.443,10,0.1,0.219,0.1,0.122,0.122,0.902,0,0,-1.4,1.6
ENSMUSG00000040370,LYRM5,LYR motif containing 5,mitochondrion|,biological_process|,molecular_function|,5,-0.2,0.506,5,0,0,-0.1,0.122,-0.122,0.902,0,0,-1.8,1.6
ENSMUSG00000040822,1700123O20RIK,RIKEN cDNA 1700123O20 gene,cellular_component|mitochondrion|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.469,-0.1,0.122,-0.122,0.902,0,0,-2,0.9
ENSMUSG00000021620,ACOT12,acyl-CoA thioesterase 12,cytoplasm|cytosol|cytosol|,acetyl-CoA metabolic process|lipid metabolic process|fatty acid metabolic process|acyl-CoA metabolic process|,acetyl-CoA hydrolase activity|acetyl-CoA hydrolase activity|ATP binding|lipid binding|hydrolase activity|,10,-0.1,0.147,10,0.1,0.114,-0.1,0.121,-0.121,0.903,0,0,-1.4,1.5
ENSMUSG00000023021,CERS5,ceramide synthase 5,nucleus|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|sphingolipid biosynthetic process|ceramide biosynthetic process|ceramide biosynthetic process|,DNA binding|transferase activity|sphingosine N-acyltransferase activity|sphingosine N-acyltransferase activity|,10,0.1,0.313,10,-0.1,0.4,-0.1,0.113,-0.113,0.904,0,0,-1.2,1.6
ENSMUSG00000033157,ABHD10,abhydrolase domain containing 10,mitochondrion|mitochondrion|cytosol|,glucuronoside catabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|hydrolase activity|",10,0,0,10,-0.1,0.109,-0.1,0.0983,-0.0983,0.907,0,0,-1.5,1.4
ENSMUSG00000031467,AGPAT5,"1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)",nucleus|mitochondrion|mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|,hematopoietic progenitor cell differentiation|lipid metabolic process|acylglycerol metabolic process|metabolic process|phospholipid biosynthetic process|,"1-acylglycerol-3-phosphate O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.1,0.38,10,0.1,0.808,0.1,0.0975,0.0975,0.907,0,0,-1.4,1.5
ENSMUSG00000053746,PTRH1,peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae),mitochondrion|,None,aminoacyl-tRNA hydrolase activity|hydrolase activity|poly(A) RNA binding|,10,0.2,0.558,10,0,0,0.1,0.0966,0.0966,0.907,0,0,-1.3,1.5
ENSMUSG00000030657,XYLT1,xylosyltransferase 1,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,glycosaminoglycan biosynthetic process|proteoglycan biosynthetic process|cellular response to heat|negative regulation of axon regeneration|,"acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|protein xylosyltransferase activity|",10,0.2,0.717,10,-0.1,0.183,-0.1,0.0938,-0.0938,0.907,0,0,-1.1,1.8
ENSMUSG00000096549,PRICKLE4,prickle homolog 4 (Drosophila),cellular_component|,biological_process|,molecular_function|,2,-0.3,0.767,2,0,0,-0.2,0.0919,-0.0919,0.907,0,0,-2,1.7
ENSMUSG00000037234,HOOK3,hook homolog 3 (Drosophila),pericentriolar material|cell|cytoplasm|cytoplasm|Golgi apparatus|cis-Golgi network|centrosome|microtubule organizing center|cytoskeleton|microtubule|HOPS complex|centriolar satellite|FHF complex|,transport|endosome organization|lysosome organization|endosome to lysosome transport|protein transport|interkinetic nuclear migration|cytoplasmic microtubule organization|microtubule anchoring at centrosome|early endosome to late endosome transport|negative regulation of neurogenesis|Golgi localization|protein localization to centrosome|neuronal stem cell maintenance|,protein binding|microtubule binding|identical protein binding|,10,0.2,0.821,10,0,0,0.1,0.0895,0.0895,0.908,0,0,-1.2,1.6
ENSMUSG00000031488,RAB11FIP1,RAB11 family interacting protein 1 (class I),cytoplasm|endosome|membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|,transport|biological_process|protein transport|,molecular_function|,10,0,0,10,0.1,0.116,0.1,0.0882,0.0882,0.908,0,0,-1.2,1.8
ENSMUSG00000032194,KANK2,KN motif and ankyrin repeat domains 2,cytoplasm|mitochondrion|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|negative regulation of cell proliferation|negative regulation of intracellular estrogen receptor signaling pathway|negative regulation of programmed cell death|negative regulation of stress fiber assembly|negative regulation of G1/S transition of mitotic cell cycle|",molecular_function|,10,0.3,1.44,10,0,0,0.1,0.0878,0.0878,0.908,0,0,-0.9,1.8
ENSMUSG00000022371,COL14A1,"collagen, type XIV, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|interstitial matrix|extracellular space|extracellular matrix|extracellular vesicular exosome|,ventricular cardiac muscle tissue development|cell adhesion|collagen fibril organization|homeostasis of number of cells within a tissue|regulation of cell growth involved in cardiac muscle cell development|,poly(A) RNA binding|,10,-0.7,2.4,10,0.1,0.179,-0.1,0.0838,-0.0838,0.909,0,0,-2,0.6
ENSMUSG00000030045,MRPL19,mitochondrial ribosomal protein L19,intracellular|nucleus|mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|nuclear membrane|,translation|,structural constituent of ribosome|,10,0.1,0.175,10,0.4,0.332,0.1,0.0795,0.0795,0.91,0,0,-0.9,1.9
ENSMUSG00000042078,SVOP,SV2 related protein,synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,transport|ion transmembrane transport|transmembrane transport|,ion transmembrane transporter activity|transmembrane transporter activity|,10,-0.1,0.332,10,-0.5,0.425,-0.2,0.0774,-0.0774,0.91,0,0,-1.9,0.8
ENSMUSG00000047842,DIRAS2,"DIRAS family, GTP-binding RAS-like 2",plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,-0.2,0.986,10,0.9,2.92,0.1,0.0714,0.0714,0.911,0,0,-0.7,2
ENSMUSG00000092009,MYH15,"myosin, heavy chain 15",myosin complex|,biological_process|,nucleotide binding|actin binding|ATP binding|,10,0.2,0.358,10,-0.1,0.587,-0.1,0.069,-0.069,0.911,0,0,-1.3,1.6
ENSMUSG00000034361,CPNE2,copine II,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.9,2.82,-0.1,0.0671,-0.0671,0.911,0,0,-0.5,2
ENSMUSG00000031982,ARV1,ARV1 homolog (yeast),cellular_component|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|bile acid metabolic process|cholesterol transport|regulation of cholesterol metabolic process|,molecular_function|,10,-0.1,0.307,10,0.1,0.598,0.1,0.0576,0.0576,0.913,0,0,-1.4,1.4
ENSMUSG00000019978,EPB4.1L2,erythrocyte protein band 4.1-like 2,cytoplasm|cytoskeleton|plasma membrane|COP9 signalosome|actin cytoskeleton|membrane|extrinsic component of membrane|extracellular vesicular exosome|,regulation of cell shape|actin cytoskeleton organization|cortical actin cytoskeleton organization|,actin binding|structural molecule activity|protein binding|cytoskeletal protein binding|spectrin binding|spectrin binding|PH domain binding|,10,-0.1,0.169,10,0.1,0.259,0.1,0.0509,0.0509,0.914,0,0,-1.5,1.4
ENSMUSG00000042473,TBC1D8B,"TBC1 domain family, member 8B",cellular_component|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|calcium ion binding|,10,0.2,0.57,10,-0.4,1.39,0.1,0.05,0.05,0.914,0,0,-1.6,1.2
ENSMUSG00000032203,PIGB,"phosphatidylinositol glycan anchor biosynthesis, class B",endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|membrane|integral component of membrane|,GPI anchor metabolic process|GPI anchor biosynthetic process|mannosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,-0.2,0.926,-0.1,0.0455,-0.0455,0.915,0,0,-1.5,1.4
ENSMUSG00000024349,TMEM173,transmembrane protein 173,cytoplasm|mitochondrion|mitochondrial outer membrane|peroxisome|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|Golgi apparatus|plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,"activation of innate immune response|activation of innate immune response|positive regulation of defense response to virus by host|immune system process|apoptotic process|positive regulation of protein binding|positive regulation of type I interferon production|interferon-beta production|interferon-beta production|positive regulation of protein import into nucleus, translocation|cellular response to interferon-beta|positive regulation of transcription factor import into nucleus|innate immune response|innate immune response|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|defense response to virus|cellular response to exogenous dsRNA|",nucleotide binding|protein binding|transcription factor binding|protein kinase binding|ubiquitin protein ligase binding|cyclic-di-GMP binding|cyclic-di-GMP binding|identical protein binding|protein homodimerization activity|cyclic-GMP-AMP binding|,10,0,0,10,0.2,0.777,0.1,0.0424,0.0424,0.916,0,0,-1.4,1.5
ENSMUSG00000032564,CPNE4,copine IV,cellular_component|,biological_process|,protein binding|,10,-0.2,0.482,10,0,0,-0.1,0.0364,-0.0364,0.917,0,0,-1.6,1.3
ENSMUSG00000052085,DOCK8,dedicator of cytokinesis 8,membrane|cell leading edge|,immunological synapse formation|small GTPase mediated signal transduction|dendritic cell migration|dendritic cell migration|positive regulation of GTPase activity|memory T cell proliferation|negative regulation of T cell apoptotic process|,guanyl-nucleotide exchange factor activity|,10,0,0,10,0.1,0.448,0.1,0.0231,0.0231,0.919,0,0,-1.1,1.8
ENSMUSG00000007122,CASQ1,calsequestrin 1,intracellular|cytoplasm|mitochondrion|mitochondrion|Golgi apparatus|terminal cisterna|terminal cisterna lumen|sarcoplasmic reticulum|sarcoplasmic reticulum|sarcoplasmic reticulum|myofibril|T-tubule|I band|sarcoplasmic reticulum lumen|sarcolemma|intracellular membrane-bounded organelle|,regulation of muscle contraction|endoplasmic reticulum organization|response to heat|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion|regulation of sequestering of calcium ion|,calcium ion binding|,10,0.2,0.252,10,0,0,-0.1,0.0225,-0.0225,0.919,0,0,-1.5,1.4
ENSMUSG00000036825,SSX2IP,"synovial sarcoma, X breakpoint 2 interacting protein",nucleus|cytoplasm|cytoskeleton|cell-cell adherens junction|cell junction|cell leading edge|centriolar satellite|protein complex|,cell adhesion|regulation of Rac protein signal transduction|centrosome organization|regulation of cell motility|,protein binding|protein domain specific binding|,10,0.2,0.571,10,0,0,0.1,0.0206,0.0206,0.919,0,0,-1.1,1.8
ENSMUSG00000029098,ACOX3,"acyl-Coenzyme A oxidase 3, pristanoyl",mitochondrion|peroxisome|peroxisomal matrix|membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|metabolic process|fatty acid beta-oxidation using acyl-CoA oxidase|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|acyl-CoA oxidase activity|receptor binding|fatty acid binding|pristanoyl-CoA oxidase activity|pristanoyl-CoA oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|flavin adenine dinucleotide binding|",10,0.2,0.92,10,0,0,0.1,0.0183,0.0183,0.92,0,0,-1.1,1.7
ENSMUSG00000007610,GTPBP3,GTP binding protein 3,intracellular|nucleus|mitochondrion|mitochondrion|,GTP catabolic process|tRNA modification|tRNA processing|,nucleotide binding|GTPase activity|GTP binding|,10,0,0,10,-0.2,1.01,-0.1,0.0153,-0.0153,0.92,0,0,-1.6,1.3
ENSMUSG00000026849,TOR1A,"torsin family 1, member A (torsin A)",nucleus|nuclear envelope|cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|cytoskeleton|synaptic vesicle|membrane|cell junction|secretory granule|growth cone|cytoplasmic vesicle membrane|cytoplasmic vesicle|nuclear membrane|extrinsic component of endoplasmic reticulum membrane|cell projection|neuron projection|intracellular membrane-bounded organelle|synapse|extracellular vesicular exosome|,"protein deneddylation|ATP catabolic process|response to oxidative stress|organelle organization|nuclear envelope organization|cell adhesion|neuron projection development|protein localization to nucleus|protein localization to nucleus|wound healing, spreading of cells|intermediate filament cytoskeleton organization|synaptic vesicle transport|chaperone mediated protein folding requiring cofactor|protein homooligomerization|protein homooligomerization|regulation of dopamine uptake involved in synaptic transmission|chaperone-mediated protein folding|ER-associated misfolded protein catabolic process|nuclear membrane organization|nuclear membrane organization|chaperone-mediated protein transport|positive regulation of synaptic vesicle endocytosis|regulation of protein localization to cell surface|",nucleotide binding|protein binding|ATP binding|cytoskeletal protein binding|cytoskeletal protein binding|hydrolase activity|ATPase activity|kinesin binding|misfolded protein binding|,10,0,0,10,-0.1,0.973,-0.1,0.0134,-0.0134,0.92,0,0,-1.4,1.5
ENSMUSG00000030470,CSRP3,cysteine and glycine-rich protein 3,nucleus|cytoplasm|cytoskeleton|Z disc|Z disc|,regulation of the force of heart contraction|cardiac muscle hypertrophy|cellular calcium ion homeostasis|multicellular organismal development|muscle organ development|cell differentiation|protein localization to organelle|protein localization to organelle|detection of muscle stretch|detection of muscle stretch|cardiac muscle tissue development|cardiac myofibril assembly|cardiac muscle contraction|cardiac muscle contraction|,protein binding|zinc ion binding|structural constituent of muscle|structural constituent of muscle|telethonin binding|telethonin binding|actinin binding|metal ion binding|,10,-0.1,0.293,10,0.1,0.506,0.1,0.0117,0.0117,0.92,0,0,-1.3,1.6
ENSMUSG00000034875,NUDT19,nudix (nucleoside diphosphate linked moiety X)-type motif 19,mitochondrion|peroxisome|,None,"thiamine-pyrophosphatase activity|receptor binding|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|",9,-0.1,0.241,9,0,0,-0.1,0.0116,-0.0116,0.92,0,0,-2,0.9
ENSMUSG00000054428,ATPIF1,ATPase inhibitory factor 1,mitochondrion|mitochondrion|mitochondrial proton-transporting ATP synthase complex|cell surface|,negative regulation of endothelial cell proliferation|heme biosynthetic process|heme biosynthetic process|erythrocyte differentiation|erythrocyte differentiation|negative regulation of nucleotide metabolic process|negative regulation of hydrolase activity|reactive oxygen species metabolic process|positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|,enzyme inhibitor activity|protein binding|ATPase inhibitor activity|angiostatin binding|ATPase binding|,10,0.9,1.96,10,0.1,0.0872,0.1,0.00941,0.00941,0.921,0,0,-0.7,2
ENSMUSG00000031505,CARKD,carbohydrate kinase domain containing,mitochondrion|,biological_process|,nucleotide binding|molecular_function|ATP binding|lyase activity|ATP-dependent NAD(P)H-hydrate dehydratase activity|,10,-0.3,1.12,10,0.1,0.234,-0.1,0.00388,-0.00388,0.922,0,0,-1.6,1.2
ENSMUSG00000051920,RSPO2,R-spondin 2 homolog (Xenopus laevis),extracellular region|cell surface|,osteoblast differentiation|Wnt signaling pathway|bone mineralization|embryonic forelimb morphogenesis|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic hindlimb morphogenesis|response to stimulus|lung growth|epithelial tube branching involved in lung morphogenesis|trachea cartilage morphogenesis|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,receptor binding|heparin binding|,10,-0.1,0.248,10,-0.7,0.232,-0.1,0.00194,-0.00194,0.922,0,0,-2,0.6
ENSMUSG00000040452,CDH12,cadherin 12,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|,calcium ion binding|metal ion binding|,10,0.1,0.136,10,0.5,0.19,0.1,9.54E-05,0.0000954,0.922,0,0,-0.7,2
ENSMUSG00000022307,OXR1,oxidation resistance 1,nucleus|nucleolus|nucleolus|mitochondrion|,adult walking behavior|negative regulation of neuron apoptotic process|oxidation-reduction process|cellular response to hydroperoxide|,oxidoreductase activity|,10,0.1,0.0828,10,-0.6,0.496,0.2,5.93E-06,0.00000593,0.922,0,0,-1.6,1.5
ENSMUSG00000045394,EPCAM,epithelial cell adhesion molecule,plasma membrane|tight junction|cell surface|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|lateral plasma membrane|cell junction|extracellular vesicular exosome|,positive regulation of cell proliferation|signal transduction involved in regulation of gene expression|positive regulation of transcription from RNA polymerase II promoter|stem cell differentiation|negative regulation of cell-cell adhesion mediated by cadherin|positive regulation of stem cell proliferation|,protein complex binding|,10,0.1,0.256,10,-1.1,2.14,0,0,0,0.922,0,0,-2,0.9
ENSMUSG00000025578,CBX8,chromobox 8,ubiquitin ligase complex|nuclear chromatin|heterochromatin|nucleus|nucleus|nucleus|PcG protein complex|PcG protein complex|PRC1 complex|,"negative regulation of transcription from RNA polymerase II promoter|chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone ubiquitination|",single-stranded RNA binding|ubiquitin-protein transferase activity|protein binding|methylated histone binding|,10,-0.4,0.06,10,-0.1,0.0822,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000001247,LSR,lipolysis stimulated lipoprotein receptor,plasma membrane|membrane|integral component of membrane|very-low-density lipoprotein particle|low-density lipoprotein particle|chylomicron|extracellular vesicular exosome|,liver development|receptor-mediated endocytosis|embryo development|regulation of lipid metabolic process|lipoprotein transport|,low-density lipoprotein particle binding|lipoprotein particle receptor activity|,10,0,0,10,0.1,0.084,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000031098,SYT8,synaptotagmin VIII,cytoplasm|plasma membrane|synaptic vesicle|membrane|integral component of membrane|cytoplasmic vesicle|membrane-bounded vesicle|,transport|acrosome reaction|,transporter activity|clathrin binding|calcium-dependent protein binding|,10,0.3,1.59,10,-0.1,0.193,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000043895,S1PR2,sphingosine-1-phosphate receptor 2,plasma membrane|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of excitatory postsynaptic membrane potential|positive regulation of establishment of endothelial barrier|,G-protein coupled receptor binding|signal transducer activity|G-protein coupled receptor activity|integrin binding|sphingosine-1-phosphate receptor activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000038342,MLXIP,MLX interacting protein,nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|nucleocytoplasmic transport|",DNA binding|protein binding|protein dimerization activity|,10,0.1,0.397,10,0,0,0,0,0,0.922,0,0,-1.8,1.2
ENSMUSG00000030546,PLIN1,perilipin 1,endoplasmic reticulum|lipid particle|lipid particle|cytosol|,lipid metabolic process|lipid catabolic process|,protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000030768,DISP1,dispatched homolog 1 (Drosophila),membrane|integral component of membrane|,smoothened signaling pathway|patched ligand maturation|patched ligand maturation|multicellular organismal development|determination of left/right symmetry|pattern specification process|embryonic pattern specification|dorsal/ventral pattern formation|dorsal/ventral pattern formation|peptide transport|peptide transport|diaphragm development|,hedgehog receptor activity|peptide transporter activity|,10,-0.1,0.419,10,0,0,0,0,0,0.922,0,0,-1.7,1.4
ENSMUSG00000071661,ZBTB3,zinc finger and BTB domain containing 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000033707,LRRC24,leucine rich repeat containing 24,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.244,0,0,0,0.922,0,0,-0.9,2
ENSMUSG00000034829,NXNL1,nucleoredoxin-like 1,nucleus|mitochondrion|membrane|,None,None,10,0,0,10,0,0,0,0,0,0.922,0,0,-0.8,2
ENSMUSG00000032232,CGNL1,cingulin-like 1,tight junction|actin cytoskeleton|myosin complex|cell junction|apical junction complex|,biological_process|,molecular_function|motor activity|,9,0,0,10,-0.8,2.13,0,0,0,0.922,0,0,-2,0.6
ENSMUSG00000020847,RPH3AL,rabphilin 3A-like (without C2 domains),cytoplasm|membrane|secretory granule|secretory granule membrane|cytoplasmic vesicle|,intracellular protein transport|exocytosis|regulation of calcium ion-dependent exocytosis|glucose homeostasis|negative regulation of G-protein coupled receptor protein signaling pathway|positive regulation of protein secretion|,protein binding|Rab GTPase binding|LIM domain binding|metal ion binding|,10,0.9,2.21,10,0,0,0,0,0,0.922,0,0,-0.4,2
ENSMUSG00000038046,RNMTL1,RNA methyltransferase like 1,mitochondrion|,RNA processing|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,-0.3,0.245,0,0,0,0.922,0,0,-1.8,1.1
ENSMUSG00000020988,L2HGDH,L-2-hydroxyglutarate dehydrogenase,mitochondrion|mitochondrion|mitochondrion|integral component of membrane|integral component of membrane|,cellular protein metabolic process|oxidation-reduction process|,oxidoreductase activity|2-hydroxyglutarate dehydrogenase activity|2-hydroxyglutarate dehydrogenase activity|,10,0.4,1.07,10,0,0,0,0,0,0.922,0,0,-0.7,2
ENSMUSG00000016552,FOXRED2,FAD-dependent oxidoreductase domain containing 2,endoplasmic reticulum|endoplasmic reticulum lumen|,ER-associated ubiquitin-dependent protein catabolic process|oxidation-reduction process|,glycoprotein binding|oxidoreductase activity|flavin adenine dinucleotide binding|,10,-0.1,0.317,10,0,0,0,0,0,0.922,0,0,-1.6,1.5
ENSMUSG00000020868,XYLT2,xylosyltransferase II,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,glycosaminoglycan biosynthetic process|proteoglycan biosynthetic process|heparin biosynthetic process|,"acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|protein xylosyltransferase activity|",10,0,0,10,0.1,0.211,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000040751,LAT2,"linker for activation of T cells family, member 2",intracellular|plasma membrane|membrane|integral component of membrane|membrane raft|membrane raft|extracellular vesicular exosome|,immune system process|calcium-mediated signaling|intracellular signal transduction|B cell activation|B cell activation|mast cell degranulation|B cell receptor signaling pathway|B cell receptor signaling pathway|,SH2 domain binding|,10,-0.1,0.0542,10,0.1,0.587,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000064254,ETHE1,ethylmalonic encephalopathy 1,nucleus|cytoplasm|mitochondrion|mitochondrion|,glutathione metabolic process|oxidation-reduction process|hydrogen sulfide metabolic process|,iron ion binding|oxidoreductase activity|metal ion binding|sulfur dioxygenase activity|dioxygenase activity|,10,0.1,0.369,10,0,0,0,0,0,0.922,0,0,-1.3,1.8
ENSMUSG00000057425,UGT2B37,"UDP glucuronosyltransferase 2 family, polypeptide B37",mitochondrial inner membrane|endoplasmic reticulum|,biological_process|,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.1,0.0169,10,0,0,0,0,0,0.922,0,0,-1.6,1.4
ENSMUSG00000024146,CRIPT,cysteine-rich PDZ-binding protein,cytoplasm|postsynaptic density|cell junction|dendrite|cell projection|neuronal cell body|dendritic spine|dendritic shaft|synapse|,cytoplasmic microtubule organization|protein localization to microtubule|establishment of protein localization|regulation of postsynaptic density protein 95 clustering|,microtubule binding|PDZ domain binding|protein complex binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.9,1.1
ENSMUSG00000049122,FRMD3,FERM domain containing 3,cellular_component|cytoplasm|cytoskeleton|membrane|integral component of membrane|extrinsic component of membrane|,biological_process|,molecular_function|cytoskeletal protein binding|,10,-0.4,0.411,10,0,0,0,0,0,0.922,0,0,-2,0.9
ENSMUSG00000037523,MAVS,mitochondrial antiviral signaling protein,intracellular|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|peroxisome|peroxisomal membrane|membrane|integral component of membrane|mitochondrial membrane|,"positive regulation of protein phosphorylation|activation of innate immune response|positive regulation of defense response to virus by host|positive regulation of defense response to virus by host|immune system process|signal transduction|signal transduction|positive regulation of type I interferon production|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|positive regulation of protein import into nucleus, translocation|RIG-I signaling pathway|defense response to bacterium|positive regulation of transcription factor import into nucleus|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of viral genome replication|negative regulation of viral genome replication|innate immune response|positive regulation of transcription from RNA polymerase II promoter|positive regulation of sequence-specific DNA binding transcription factor activity|defense response to virus|positive regulation of type I interferon-mediated signaling pathway|cellular response to exogenous dsRNA|positive regulation of chemokine (C-C motif) ligand 5 production|positive regulation of IP-10 production|regulation of peroxisome organization|regulation of peroxisome organization|",signal transducer activity|signal transducer activity|protein binding|protein kinase binding|CARD domain binding|,10,-0.1,0.137,10,0,0,0,0,0,0.922,0,0,-1.6,1.3
ENSMUSG00000029491,PDE6B,"phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide",membrane|,signal transduction|visual perception|detection of light stimulus|GMP metabolic process|response to stimulus|cytosolic calcium ion homeostasis|retina development in camera-type eye|,"3',5'-cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|3',5'-cyclic-GMP phosphodiesterase activity|",9,0,0,9,-0.6,2.05,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000031246,SH3BGRL,SH3-binding domain glutamic acid-rich protein like,extracellular space|extracellular vesicular exosome|,biological_process|,molecular_function|SH3 domain binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000024511,RAB27B,"RAB27B, member RAS oncogene family",Golgi apparatus|Golgi stack|membrane|apical plasma membrane|trans-Golgi network transport vesicle|secretory granule membrane|multivesicular body membrane|zymogen granule membrane|extracellular vesicular exosome|,GTP catabolic process|small GTPase mediated signal transduction|protein transport|regulation of exocytosis|positive regulation of exocytosis|multivesicular body sorting pathway|,nucleotide binding|GTPase activity|protein binding|GTP binding|GTP binding|GDP binding|protein domain specific binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000022765,SNAP29,synaptosomal-associated protein 29,cytoplasm|centrosome|membrane|cell junction|SNARE complex|neuron projection|synapse|,autophagic vacuole fusion|transport|autophagy|protein transport|,syntaxin binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000029152,OCIAD1,OCIA domain containing 1,mitochondrion|endosome|membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.6,1.5
ENSMUSG00000029314,AGPAT9,1-acylglycerol-3-phosphate O-acyltransferase 9,endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,lipid metabolic process|metabolic process|phospholipid biosynthetic process|triglyceride biosynthetic process|triglyceride biosynthetic process|regulation of TOR signaling|,"1-acylglycerol-3-phosphate O-acyltransferase activity|glycerol-3-phosphate O-acyltransferase activity|glycerol-3-phosphate O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.4,1.29,10,0.3,1.27,0,0,0,0.922,0,0,-1.7,1.2
ENSMUSG00000022048,DPYSL2,dihydropyrimidinase-like 2,cytoplasm|mitochondrion|cytosol|cytoskeleton|microtubule|membrane|axon|dendrite|dendrite|growth cone|neuron projection|neuronal cell body|neuronal cell body|terminal bouton|protein complex|extracellular vesicular exosome|,pyrimidine nucleobase catabolic process|endocytosis|cytoskeleton organization|multicellular organismal development|nervous system development|positive regulation of glutamate secretion|cell differentiation|regulation of neuron differentiation|synaptic vesicle transport|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|protein kinase binding|",10,0.1,0.415,10,-0.2,0.57,0,0,0,0.922,0,0,-1.3,1.6
ENSMUSG00000089943,UGT1A5,"UDP glucuronosyltransferase 1 family, polypeptide A5",endoplasmic reticulum|,cellular glucuronidation|,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|enzyme binding|protein homodimerization activity|protein heterodimerization activity|",5,0,0,5,0,0,0,0,0,0.922,0,0,-1.5,1.9
ENSMUSG00000038515,GRTP1,GH regulated TBC protein 1,None,regulation of Rab GTPase activity|,GTPase activator activity|Rab GTPase activator activity|,10,0.2,0.0334,10,0,0,0,0,0,0.922,0,0,-1.1,1.9
ENSMUSG00000030732,CHRDL2,chordin-like 2,extracellular region|extracellular space|,ossification|multicellular organismal development|cell differentiation|negative regulation of BMP signaling pathway|cartilage development|,protein binding|,10,0.1,0.215,10,-0.1,0.148,0,0,0,0.922,0,0,-1.2,1.7
ENSMUSG00000035592,KRT33A,keratin 33A,extracellular space|intermediate filament|,biological_process|,structural molecule activity|protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1,1.9
ENSMUSG00000026142,RHBDD1,rhomboid domain containing 1,mitochondrion|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|endoplasmic reticulum quality control compartment|,proteolysis|apoptotic process|spermatogenesis|positive regulation of protein processing|cell differentiation|ER-associated ubiquitin-dependent protein catabolic process|membrane protein intracellular domain proteolysis|membrane protein proteolysis|membrane protein proteolysis|cellular response to unfolded protein|cellular response to UV|negative regulation of apoptotic process|negative regulation of apoptotic process|post-translational protein modification|positive regulation of protein catabolic process|positive regulation of protein catabolic process|spermatid differentiation|positive regulation of secretion|positive regulation of secretion|,endopeptidase activity|endopeptidase activity|serine-type endopeptidase activity|serine-type endopeptidase activity|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.0213,10,0.1,0.596,0,0,0,0.922,0,0,-1.7,1.2
ENSMUSG00000035606,KY,kyphoscoliosis peptidase,cytoplasm|cytoskeleton|Z disc|,proteolysis|muscle organ development|neuromuscular junction development|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000006930,HAP1,huntingtin-associated protein 1,intracellular|cell|cytoplasmic membrane-bounded vesicle|dendrite|growth cone|neuron projection|axon terminus|perinuclear region of cytoplasm|,protein localization|positive regulation of neuron projection development|vesicle transport along microtubule|,receptor binding|protein binding|protein domain specific binding|,10,0,0,10,0.1,0.0346,0,0,0,0.922,0,0,-1.1,1.9
ENSMUSG00000039103,NEXN,nexilin,cytoplasm|cytoskeleton|cell-substrate adherens junction|Z disc|Z disc|cell junction|,protein phosphorylation|regulation of cell migration|regulation of cell migration|cardiac muscle fiber development|regulation of cytoskeleton organization|,actin binding|calmodulin-dependent protein kinase activity|structural constituent of muscle|actin filament binding|actin filament binding|,10,0.1,0.03,10,0,0,0,0,0,0.922,0,0,-1.2,1.7
ENSMUSG00000025277,ABHD6,abhydrolase domain containing 6,mitochondrion|membrane|integral component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|extracellular vesicular exosome|,negative regulation of cell migration|long term synaptic depression|regulation of endocannabinoid signaling pathway|,catalytic activity|hydrolase activity|acylglycerol lipase activity|acylglycerol lipase activity|,10,0.2,0.637,10,0,0,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000011751,SPTBN4,"spectrin beta, non-erythrocytic 4",cytoplasm|cytoplasm|plasma membrane|adherens junction|spectrin|spectrin|membrane|nuclear matrix|nuclear matrix|PML body|PML body|axon|node of Ranvier|node of Ranvier|paranode region of axon|neuronal cell body|axon initial segment|axon initial segment|axon hillock|cell body fiber|,regulation of sodium ion transport|axonogenesis|sensory perception of sound|adult walking behavior|fertilization|negative regulation of heart rate|transmission of nerve impulse|central nervous system projection neuron axonogenesis|reproductive process|adult behavior|regulation of peptidyl-serine phosphorylation|cellular protein localization|positive regulation of multicellular organism growth|clustering of voltage-gated sodium channels|cardiac conduction|establishment of protein localization to plasma membrane|,actin binding|protein binding|phosphatase binding|ankyrin binding|ankyrin binding|ankyrin binding|spectrin binding|,10,0.2,0.886,10,0,0,0,0,0,0.922,0,0,-2,1
ENSMUSG00000026028,TRAK2,"trafficking protein, kinesin binding 2",nucleus|cytoplasm|mitochondrion|plasma membrane|,regulation of transcription from RNA polymerase II promoter|protein O-linked glycosylation|protein targeting|,receptor binding|enzyme binding|GABA receptor binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000003411,RAB3B,"RAB3B, member RAS oncogene family",cytoplasm|cytosol|plasma membrane|synaptic vesicle|membrane|secretory granule|vesicle|perinuclear region of cytoplasm|extracellular vesicular exosome|,transport|small GTPase mediated signal transduction|protein transport|regulation of exocytosis|peptidyl-cysteine methylation|antigen processing and presentation|positive regulation of dopamine uptake involved in synaptic transmission|regulation of vesicle size|,nucleotide binding|protein binding|GTP binding|GDP binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000031556,TM2D2,TM2 domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.467,10,0,0,0,0,0,0.922,0,0,-1,1.9
ENSMUSG00000043155,HPDL,4-hydroxyphenylpyruvate dioxygenase-like,cellular_component|,biological_process|aromatic amino acid family metabolic process|oxidation-reduction process|,"molecular_function|4-hydroxyphenylpyruvate dioxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen|3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity|1,2-dihydroxynaphthalene dioxygenase activity|1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity|1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity|1,2-dihydroxy-8-methylnaphthalene dioxygenase activity|2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity|2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity|metal ion binding|dioxygenase activity|",10,0.1,0.62,10,0,0,0,0,0,0.922,0,0,-1.1,1.9
ENSMUSG00000043162,PYURF,Pigy upstream reading frame,glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|mitochondrion|endoplasmic reticulum membrane|endoplasmic reticulum membrane|plasma membrane|,GPI anchor biosynthetic process|GPI anchor biosynthetic process|positive regulation of metabolic process|,molecular_function|,10,0,0,10,0.1,0.0884,0,0,0,0.922,0,0,-1.4,1.6
ENSMUSG00000039714,CPLX3,complexin 3,cell|cytosol|plasma membrane|membrane|cell junction|synapse|,transport|neurotransmitter transport|exocytosis|synaptic vesicle exocytosis|insulin secretion|regulation of neurotransmitter secretion|,SNARE binding|neurotransmitter transporter activity|syntaxin binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000007041,CLIC1,chloride intracellular channel 1,extracellular space|nucleus|nuclear envelope|cytoplasm|mitochondrion|plasma membrane|membrane|membrane|integral component of membrane|chloride channel complex|perinuclear region of cytoplasm|extracellular vesicular exosome|blood microparticle|,transport|ion transport|chloride transport|regulation of ion transmembrane transport|positive regulation of osteoblast differentiation|regulation of mitochondrial membrane potential|regulation of mitochondrial membrane potential|chloride transmembrane transport|,voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|,10,0,0,10,0.1,0.18,0,0,0,0.922,0,0,-1,1.9
ENSMUSG00000020913,KRT24,keratin 24,cytoplasm|intermediate filament|intermediate filament cytoskeleton|,biological_process|,structural molecule activity|,10,0.1,0.554,10,0,0,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000020570,SYPL,synaptophysin-like protein,synaptic vesicle|membrane|integral component of membrane|secretory granule|integral component of synaptic vesicle membrane|cytoplasmic vesicle|extracellular vesicular exosome|,transport|,transporter activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-0.8,2
ENSMUSG00000063698,SFXN4,sideroflexin 4,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,transport|ion transport|cation transport|biological_process|iron ion homeostasis|transmembrane transport|,molecular_function|cation transmembrane transporter activity|,10,-0.1,0.125,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000041126,H2AFV,"H2A histone family, member V",nucleosome|nucleus|chromosome|,biological_process|,DNA binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.7
ENSMUSG00000029923,RAB19,"RAB19, member RAS oncogene family",plasma membrane|membrane|extracellular vesicular exosome|,small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTP binding|,10,-0.2,0.752,10,0.3,0.921,0,0,0,0.922,0,0,-1.1,1.8
ENSMUSG00000057723,KRT33B,keratin 33B,extracellular space|intermediate filament|,None,structural molecule activity|,10,0,0,10,0.3,0.828,0,0,0,0.922,0,0,-0.8,2
ENSMUSG00000062797,L7RN6,"lethal, Chr 7, Rinchik 6",intracellular|nucleus|cytoplasm|cytosol|cell junction|extracellular vesicular exosome|,protein import into nucleus|transport|Golgi organization|protein transport|lung development|cellular response to heat|,protein transporter activity|Hsp70 protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.8,1.3
ENSMUSG00000026475,RGS16,regulator of G-protein signaling 16,cytoplasm|cytoplasm|plasma membrane|membrane raft|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.7,1.4
ENSMUSG00000090145,UGT1A6B,"UDP glucuronosyltransferase 1 family, polypeptide A6B",endoplasmic reticulum|intracellular membrane-bounded organelle|protein complex|extracellular vesicular exosome|,biological_process|,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|enzyme binding|protein complex binding|protein homodimerization activity|protein heterodimerization activity|",5,0,0,5,0,0,0,0,0,0.922,0,0,-1.9,1.6
ENSMUSG00000038742,ANGPTL6,angiopoietin-like 6,extracellular region|secretory granule|,angiogenesis|multicellular organismal development|cell differentiation|,None,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000025158,RFNG,RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|extracellular vesicular exosome|,multicellular organismal development|pattern specification process|nervous system development|cell differentiation|positive regulation of protein binding|negative regulation of Notch signaling pathway|positive regulation of Notch signaling pathway|,"transferase activity|transferase activity, transferring glycosyl groups|O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity|metal ion binding|",10,0.1,0.14,10,0,0,0,0,0,0.922,0,0,-1.3,1.8
ENSMUSG00000091813,CES2H,carboxylesterase 2H,cellular_component|,biological_process|,hydrolase activity|carboxylic ester hydrolase activity|,10,-0.1,0.0334,10,0,0,0,0,0,0.922,0,0,-1,1.9
ENSMUSG00000033021,GMPPA,GDP-mannose pyrophosphorylase A,cellular_component|cytoplasm|,biosynthetic process|,molecular_function|transferase activity|nucleotidyltransferase activity|,10,0,0,10,0.3,0.364,0,0,0,0.922,0,0,-1,1.8
ENSMUSG00000031819,EMC8,ER membrane protein complex subunit 8,cytoplasm|mitochondrion|membrane|ER membrane protein complex|,biological_process|,molecular_function|,5,0,0,5,0,0,0,0,0,0.922,0,0,-1.6,1.8
ENSMUSG00000002289,ANGPTL4,angiopoietin-like 4,extracellular region|extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|blood microparticle|,angiogenesis|cellular response to starvation|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of lipid metabolic process|negative regulation of lipoprotein lipase activity|negative regulation of lipoprotein lipase activity|protein homooligomerization|triglyceride homeostasis|negative regulation of endothelial cell apoptotic process|,enzyme inhibitor activity|,10,0,0,10,0.4,0.35,0,0,0,0.922,0,0,-0.9,1.9
ENSMUSG00000032470,MRAS,muscle and microspikes RAS,plasma membrane|membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|,nucleotide binding|GTP binding|GTP-dependent protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1,2
ENSMUSG00000031861,LPAR2,lysophosphatidic acid receptor 2,cell surface|membrane|integral component of membrane|endocytic vesicle|,activation of MAPK activity|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of Rho protein signal transduction|positive regulation of MAPK cascade|,signal transducer activity|G-protein coupled receptor activity|PDZ domain binding|,10,0,0,10,0.3,0.71,0,0,0,0.922,0,0,-1,1.9
ENSMUSG00000037697,DDHD1,DDHD domain containing 1,cellular_component|cytoplasm|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|metal ion binding|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0,0,10,-0.1,0.207,0,0,0,0.922,0,0,-1.7,1.4
ENSMUSG00000061802,ARMC4,armadillo repeat containing 4,nucleus|cytoplasm|cytoskeleton|cilium|axoneme|cell projection|ciliary base|,cilium movement|ventricular system development|cell projection organization|outer dynein arm assembly|left/right axis specification|,molecular_function|,9,0.2,0.335,9,0,0,0,0,0,0.922,0,0,-1.3,1.8
ENSMUSG00000032556,BFSP2,"beaded filament structural protein 2, phakinin",cytoplasm|cytoplasm|cytoskeleton|intermediate filament|plasma membrane|membrane|,cytoskeleton organization|visual perception|intermediate filament cytoskeleton organization|cell maturation|response to stimulus|lens fiber cell development|,structural molecule activity|structural constituent of eye lens|protein binding|,10,0.2,0.0704,10,0,0,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000025155,DUS1L,dihydrouridine synthase 1-like (S. cerevisiae),cellular_component|,tRNA processing|oxidation-reduction process|,"catalytic activity|oxidoreductase activity|enoyl-[acyl-carrier-protein] reductase activity|tRNA dihydrouridine synthase activity|2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity|cis-2,3-dihydrodiol DDT dehydrogenase activity|trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity|cis-chlorobenzene dihydrodiol dehydrogenase activity|2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity|trans-1,2-dihydrodiolphenanthrene dehydrogenase activity|3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity|benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity|benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity|citronellyl-CoA dehydrogenase activity|menthone dehydrogenase activity|phthalate 3,4-cis-dihydrodiol dehydrogenase activity|cinnamate reductase activity|flavin adenine dinucleotide binding|NADPH-dependent curcumin reductase activity|NADPH-dependent dihydrocurcumin reductase activity|",10,0.1,0.0787,10,-0.6,0.817,0,0,0,0.922,0,0,-1.9,1
ENSMUSG00000020911,KRT19,keratin 19,intermediate filament|dystrophin-associated glycoprotein complex|Z disc|sarcolemma|costamere|extracellular vesicular exosome|cell periphery|,sarcomere organization|cell differentiation involved in embryonic placenta development|,structural molecule activity|structural constituent of muscle|protein complex binding|,10,-0.1,0.247,10,0.1,0.435,0,0,0,0.922,0,0,-1.4,1.6
ENSMUSG00000018554,YBX2,Y box protein 2,nucleus|cytoplasm|cytoplasm|polysome|ribonucleoprotein complex|,"regulation of transcription, DNA-templated|spermatid development|negative regulation of translation|mRNA stabilization|oogenesis|negative regulation of binding|",nucleic acid binding|DNA binding|chromatin binding|RNA binding|mRNA binding|mRNA 3'-UTR binding|lipid binding|ribonucleoprotein complex binding|translation regulator activity|,10,0,0,10,-0.2,1.18,0,0,0,0.922,0,0,-1.5,1.4
ENSMUSG00000060376,BCKDHA,"branched chain ketoacid dehydrogenase E1, alpha polypeptide",mitochondrion|mitochondrion|mitochondrial alpha-ketoglutarate dehydrogenase complex|,metabolic process|branched-chain amino acid catabolic process|oxidation-reduction process|,"alpha-ketoacid dehydrogenase activity|3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor|protein complex binding|metal ion binding|",10,-0.1,0.0992,10,0,0,0,0,0,0.922,0,0,-1.7,1.2
ENSMUSG00000022878,ADIPOQ,"adiponectin, C1Q and collagen domain containing",extracellular region|collagen trimer|extracellular space|extracellular space|endoplasmic reticulum|cell surface|extracellular vesicular exosome|,"positive regulation of protein phosphorylation|glucose metabolic process|glucose metabolic process|fatty acid beta-oxidation|response to glucose|response to glucose|positive regulation of signal transduction|negative regulation of platelet-derived growth factor receptor signaling pathway|negative regulation of platelet-derived growth factor receptor signaling pathway|positive regulation of protein kinase A signaling|negative regulation of macrophage derived foam cell differentiation|negative regulation of tumor necrosis factor-mediated signaling pathway|positive regulation of cholesterol efflux|regulation of glucose metabolic process|negative regulation of smooth muscle cell migration|fatty acid oxidation|negative regulation of cell migration|negative regulation of granulocyte differentiation|negative regulation of protein autophosphorylation|positive regulation of cellular protein metabolic process|negative regulation of tumor necrosis factor production|positive regulation of interleukin-8 production|cellular response to insulin stimulus|cellular response to insulin stimulus|positive regulation of myeloid cell apoptotic process|adiponectin-activated signaling pathway|negative regulation of heterotypic cell-cell adhesion|low-density lipoprotein particle clearance|response to tumor necrosis factor|cellular response to drug|glucose homeostasis|glucose homeostasis|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of MAP kinase activity|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|negative regulation of macrophage differentiation|negative regulation of low-density lipoprotein particle receptor biosynthetic process|negative regulation of gluconeogenesis|negative regulation of blood pressure|positive regulation of blood pressure|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of fatty acid metabolic process|positive regulation of glucose import|negative regulation of hormone secretion|negative regulation of smooth muscle cell proliferation|negative regulation of inflammatory response|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of phagocytosis|negative regulation of synaptic transmission|brown fat cell differentiation|protein homooligomerization|membrane depolarization|membrane hyperpolarization|protein heterotrimerization|negative regulation of ERK1 and ERK2 cascade|detection of oxidative stress|cellular response to cAMP|positive regulation of monocyte chemotactic protein-1 production|cellular response to epinephrine stimulus|protein localization to plasma membrane|negative regulation of intracellular protein transport|negative regulation of receptor binding|negative regulation of DNA biosynthetic process|positive regulation of glycogen (starch) synthase activity|positive regulation of metanephric glomerular visceral epithelial cell development|positive regulation of cAMP-dependent protein kinase activity|positive regulation of cAMP-dependent protein kinase activity|positive regulation of renal albumin absorption|positive regulation of renal albumin absorption|negative regulation of platelet-derived growth factor receptor-alpha signaling pathway|negative regulation of metanephric mesenchymal cell migration|",receptor binding|hormone activity|hormone activity|hormone activity|protein binding|sialic acid binding|identical protein binding|protein homodimerization activity|,10,-0.2,1.06,10,0,0,0,0,0,0.922,0,0,-1.7,1.2
ENSMUSG00000020961,STON2,stonin 2,nucleolus|cytoplasm|synaptic vesicle|membrane|cell junction|clathrin adaptor complex|clathrin-coated vesicle|neuron projection|synapse|,hematopoietic progenitor cell differentiation|intracellular protein transport|endocytosis|synaptic transmission|vesicle-mediated transport|regulation of endocytosis|synaptic vesicle endocytosis|,protein binding|,10,0,0,10,-0.1,0.209,0,0,0,0.922,0,0,-1.9,1
ENSMUSG00000033847,PLA2G4C,"phospholipase A2, group IVC (cytosolic, calcium-independent)",nuclear envelope|nucleoplasm|cell cortex|,glycerophospholipid catabolic process|,calcium-independent phospholipase A2 activity|,10,0,0,10,0.1,0.496,0,0,0,0.922,0,0,-1.3,1.6
ENSMUSG00000070639,LRRC8B,"leucine rich repeat containing 8 family, member B",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0,0,10,-0.6,0.593,0,0,0,0.922,0,0,-2,0.7
ENSMUSG00000021078,TOMM20L,translocase of outer mitochondrial membrane 20 homolog (yeast)-like,mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane translocase complex|membrane|integral component of membrane|,protein targeting|intracellular protein transport|,molecular_function|,10,0.3,0.138,10,0,0,0,0,0,0.922,0,0,-0.8,2
ENSMUSG00000036523,GREB1,gene regulated by estrogen in breast cancer protein,membrane|integral component of membrane|,None,None,10,0.4,0.856,10,0,0,0,0,0,0.922,0,0,-0.8,2
ENSMUSG00000041642,KIF21B,kinesin family member 21B,cytoplasm|cytoskeleton|kinesin complex|microtubule|cell projection|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000028758,KIF17,kinesin family member 17,intracellular|cell|cytoplasm|cytoskeleton|kinesin complex|microtubule|cilium|axoneme|microtubule cytoskeleton|intraciliary transport particle B|photoreceptor connecting cilium|ciliary basal body|ciliary basal body|periciliary membrane compartment|,transport|microtubule-based process|microtubule-based movement|protein transport|vesicle-mediated transport|protein complex localization|intraciliary transport|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|,10,0.1,0.28,10,0,0,0,0,0,0.922,0,0,-1.2,1.7
ENSMUSG00000036718,MICALL2,MICAL-like 2,stress fiber|intracellular|cell|cytoplasm|endosome|cytoskeleton|plasma membrane|cell-cell junction|tight junction|membrane|cell junction|actin filament bundle|cell projection|neuron projection|recycling endosome|,actin filament polymerization|actin filament polymerization|neuron projection development|neuron projection development|actin cytoskeleton reorganization|endocytic recycling|endocytic recycling|substrate adhesion-dependent cell spreading|tight junction assembly|,protein binding|zinc ion binding|Rab GTPase binding|filamin binding|filamin binding|actinin binding|metal ion binding|actin filament binding|,10,0,0,10,-0.1,0.149,0,0,0,0.922,0,0,-1.6,1.4
ENSMUSG00000052369,TMEM106C,transmembrane protein 106C,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000036295,LRRN3,"leucine rich repeat protein 3, neuronal",plasma membrane|membrane|integral component of membrane|clathrin adaptor complex|,positive regulation of protein phosphorylation|,protein complex binding|,10,0.1,0.386,10,-0.1,0.505,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000053411,CBX7,chromobox 7,nuclear chromatin|heterochromatin|nucleus|nucleus|cytoplasm|PcG protein complex|PRC1 complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|sebaceous gland development|",chromatin binding|RNA binding|single-stranded RNA binding|methylated histone binding|,10,0.2,0.614,10,0,0,0,0,0,0.922,0,0,-1.3,1.8
ENSMUSG00000090425,EFNA5,ephrin A5,plasma membrane|membrane|anchored component of membrane|anchored component of external side of plasma membrane|anchored component of plasma membrane|,multicellular organismal development|nervous system development|axon guidance|axon guidance|brain development|regulation of cell-cell adhesion|regulation of cell-cell adhesion|cell differentiation|retinal ganglion cell axon guidance|regulation of Rac GTPase activity|regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|regulation of actin cytoskeleton organization|ephrin receptor signaling pathway|ephrin receptor signaling pathway|positive regulation of peptidyl-tyrosine phosphorylation|negative chemotaxis|regulation of focal adhesion assembly|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of microtubule cytoskeleton organization|,protein binding|chemorepellent activity|ephrin receptor binding|ephrin receptor binding|,10,-0.1,0.0255,10,0,0,0,0,0,0.922,0,0,-1.8,1
ENSMUSG00000029128,RAB28,"RAB28, member RAS oncogene family",cellular_component|cytoplasm|cytoskeleton|plasma membrane|membrane|ciliary rootlet|ciliary basal body|cell projection|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|GDP binding|,10,-0.2,0.5,10,0,0,0,0,0,0.922,0,0,-1.7,1.1
ENSMUSG00000045007,TUBG2,"tubulin, gamma 2",pericentriolar material|gamma-tubulin complex|cytoplasm|centrosome|cytoskeleton|microtubule|spindle microtubule|cytoplasmic microtubule|protein complex|,GTP catabolic process|microtubule-based process|microtubule nucleation|cytoplasmic microtubule organization|protein polymerization|,nucleotide binding|GTPase activity|GTP binding|,9,-0.2,0.188,9,0,0,0,0,0,0.922,0,0,-1.8,1.2
ENSMUSG00000030770,PARVA,"parvin, alpha",nucleus|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|focal adhesion|actin cytoskeleton|membrane|lamellipodium|cell junction|protein complex|,angiogenesis|sprouting angiogenesis|outflow tract septum morphogenesis|chemotaxis|cell adhesion|establishment or maintenance of cell polarity|regulation of cell shape|cell projection organization|actin cytoskeleton organization|actin cytoskeleton reorganization|heterotypic cell-cell adhesion|substrate adhesion-dependent cell spreading|substrate adhesion-dependent cell spreading|protein heterooligomerization|cilium morphogenesis|actin-mediated cell contraction|smooth muscle cell chemotaxis|,actin binding|protein binding|,10,-0.2,0.941,10,0.2,0.631,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000034467,DYNLRB2,dynein light chain roadblock-type 2,cytoplasm|cytoskeleton|cytoplasmic dynein complex|microtubule|dynein complex|extracellular vesicular exosome|,transport|biological_process|,motor activity|protein binding|,10,-0.1,0.0506,10,0,0,0,0,0,0.922,0,0,-1.7,1.3
ENSMUSG00000047507,BAIAP3,BAI1-associated protein 3,cellular_component|,G-protein coupled receptor signaling pathway|,molecular_function|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.7,1.4
ENSMUSG00000048142,NAT8L,N-acetyltransferase 8-like,cytoplasm|mitochondrion|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|mitochondrial membrane|intracellular membrane-bounded organelle|,metabolic process|positive regulation of dopamine uptake involved in synaptic transmission|,"N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|aspartate N-acetyltransferase activity|aspartate N-acetyltransferase activity|",10,0,0,10,-0.1,0.339,0,0,0,0.922,0,0,-1.5,1.5
ENSMUSG00000028467,GBA2,glucosidase beta 2,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|glucosylceramide catabolic process|metabolic process|bile acid metabolic process|glycoside catabolic process|central nervous system neuron development|,"catalytic activity|glucosylceramidase activity|beta-glucosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.3,0.481,10,0,0,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000024736,TMEM132A,transmembrane protein 132A,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,negative regulation of programmed cell death|,molecular_function|,10,0.2,0.171,10,-0.9,1.45,0,0,0,0.922,0,0,-2,1.2
ENSMUSG00000007907,CABS1,"calcium binding protein, spermatid specific 1",cytoplasm|mitochondrion|mitochondrial inner membrane|motile cilium|cell projection|,spermatogenesis|biological_process|,calcium ion binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.1,1.9
ENSMUSG00000035954,DOCK4,dedicator of cytokinesis 4,cytoplasm|cytosol|membrane|stereocilium|stereocilium bundle|,small GTPase mediated signal transduction|positive regulation of Rac GTPase activity|cell chemotaxis|,guanyl-nucleotide exchange factor activity|SH3 domain binding|PDZ domain binding|Rac GTPase activator activity|receptor tyrosine kinase binding|Rac GTPase binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000021460,AUH,AU RNA binding protein/enoyl-coenzyme A hydratase,mitochondrion|,"nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|metabolic process|branched-chain amino acid catabolic process|",RNA binding|mRNA 3'-UTR binding|catalytic activity|enoyl-CoA hydratase activity|enoyl-CoA hydratase activity|methylglutaconyl-CoA hydratase activity|lyase activity|,10,0.1,0.432,10,0,0,0,0,0,0.922,0,0,-1.6,1.4
ENSMUSG00000092164,RERGL,RERG/RAS-like,cellular_component|,biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0.1,0.00342,10,0,0,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000015488,CACFD1,calcium channel flower domain containing 1,cellular_component|membrane|integral component of membrane|integral component of synaptic vesicle membrane|,biological_process|synaptic vesicle endocytosis|,molecular_function|calcium channel activity|,10,0.1,0.232,10,0,0,0,0,0,0.922,0,0,-1.3,1.8
ENSMUSG00000021738,ATXN7,ataxin 7,nucleus|nucleus|cytoplasm|cytoplasm|cytoskeleton|microtubule cytoskeleton|,"microtubule cytoskeleton organization|transcription, DNA-templated|regulation of transcription, DNA-templated|histone deubiquitination|negative regulation of phosphorylation|negative regulation of insulin-like growth factor receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|",chromatin binding|protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.7,1.4
ENSMUSG00000014503,PKD2L2,polycystic kidney disease 2-like 2,membrane|integral component of membrane|,transport|ion transport|detection of mechanical stimulus|calcium ion transmembrane transport|,calcium channel activity|calcium ion binding|,10,-0.1,0.00706,10,0,0,0,0,0,0.922,0,0,-1.7,1.4
ENSMUSG00000079685,ULBP1,UL16 binding protein 1,integral component of plasma membrane|external side of plasma membrane|anchored component of plasma membrane|,positive regulation of immune response to tumor cell|natural killer cell activation|positive regulation of interferon-gamma production|positive regulation of natural killer cell activation|natural killer cell mediated cytotoxicity|susceptibility to natural killer cell mediated cytotoxicity|positive regulation of macrophage activation|positive regulation of nitric oxide biosynthetic process|,natural killer cell lectin-like receptor binding|natural killer cell lectin-like receptor binding|,10,0.1,0.0837,10,-0.1,0.271,0,0,0,0.922,0,0,-1.2,1.7
ENSMUSG00000044518,FOXE3,forkhead box E3,nucleus|transcription factor complex|,"eye development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|camera-type eye development|cell development|positive regulation of epithelial cell proliferation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,-0.1,0.297,0,0,0,0.922,0,0,-1.7,1.3
ENSMUSG00000016637,IFT27,intraflagellar transport 27,intracellular|cell|centrosome|cilium|cilium|intraciliary transport particle B|cell projection|sperm midpiece|sperm principal piece|,small GTPase mediated signal transduction|intraciliary transport|,nucleotide binding|protein binding|GTP binding|,10,0,0,10,-0.1,0.201,0,0,0,0.922,0,0,-1.6,1.4
ENSMUSG00000042102,DMGDH,dimethylglycine dehydrogenase precursor,cytoplasm|mitochondrion|mitochondrion|,glycine metabolic process|glycine catabolic process|tetrahydrofolate interconversion|oxidation-reduction process|,aminomethyltransferase activity|folic acid binding|oxidoreductase activity|poly(A) RNA binding|dimethylglycine dehydrogenase activity|flavin adenine dinucleotide binding|,10,0.1,0.0282,10,-0.1,0.391,0,0,0,0.922,0,0,-1.2,1.7
ENSMUSG00000018620,MMP20,matrix metallopeptidase 20 (enamelysin),extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|extracellular matrix disassembly|protein catabolic process|amelogenesis|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000032109,NLRX1,NLR family member X1,mitochondrion|mitochondrial outer membrane|membrane|,immune system process|viral process|negative regulation of interferon-beta production|negative regulation of interleukin-6 production|negative regulation of RIG-I signaling pathway|negative regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|negative regulation of innate immune response|negative regulation of inflammatory response|,nucleotide binding|protein binding|ATP binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000028102,PEX11B,peroxisomal biogenesis factor 11 beta,mitochondrion|peroxisome|peroxisomal membrane|integral component of peroxisomal membrane|membrane|membrane|integral component of membrane|protein complex|extracellular vesicular exosome|,peroxisome organization|cell adhesion|integrin-mediated signaling pathway|peroxisome fission|regulation of peroxisome size|protein homooligomerization|,protein homodimerization activity|,10,0.2,0.726,10,0,0,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000004187,KIFC2,kinesin family member C2,cytoplasm|cytoskeleton|kinesin complex|microtubule|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,0,0,10,-0.1,0.532,0,0,0,0.922,0,0,-1.3,1.6
ENSMUSG00000053253,NDFIP2,Nedd4 family interacting protein 2,cytoplasm|mitochondrion|endosome|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,signal transduction|negative regulation of gene expression|positive regulation of protein ubiquitination|negative regulation of transporter activity|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of protein transport|,signal transducer activity|WW domain binding|,10,0.2,0.723,10,0,0,0,0,0,0.922,0,0,-1.3,1.6
ENSMUSG00000090000,IER3IP1,immediate early response 3 interacting protein 1,endoplasmic reticulum|Golgi apparatus|membrane|membrane|integral component of membrane|,regulation of fibroblast apoptotic process|,molecular_function|,10,0.1,0.203,10,0,0,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000026676,CCDC3,coiled-coil domain containing 3,extracellular region|endoplasmic reticulum|,biological_process|,molecular_function|,10,0.2,0.358,10,0,0,0,0,0,0.922,0,0,-1.3,1.6
ENSMUSG00000062309,RPP25,ribonuclease P/MRP 25 subunit,nucleus|,tRNA processing|biological_process|,nucleic acid binding|RNA binding|ribonuclease P activity|hydrolase activity|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000037737,ACTRT3,actin related protein T3,male germ cell nucleus|nucleus|cytoplasm|cytoskeleton|,None,protein binding|,10,0,0,10,-0.1,0.376,0,0,0,0.922,0,0,-1.7,1.3
ENSMUSG00000022032,SCARA5,"scavenger receptor class A, member 5 (putative)",plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|,transport|ion transport|cellular iron ion homeostasis|endocytosis|receptor-mediated endocytosis|regulation of gene expression|regulation of blood coagulation|cellular response to heat|iron ion transmembrane transport|iron ion homeostasis|protein homotrimerization|,scavenger receptor activity|protein binding|ferritin receptor activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.6,1.5
ENSMUSG00000048330,RIC3,resistance to inhibitors of cholinesterase 3 homolog (C. elegans),endoplasmic reticulum|membrane|integral component of membrane|,"protein folding|positive regulation of cytosolic calcium ion concentration|synaptic transmission, cholinergic|cellular protein complex assembly|",acetylcholine receptor binding|protein binding involved in protein folding|,10,0,0,10,0.1,0.0432,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000028228,CPNE3,copine III,cytosol|extracellular vesicular exosome|,protein phosphorylation|,protein serine/threonine kinase activity|poly(A) RNA binding|,10,0.1,0.0194,10,-0.7,0.485,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000038936,SCCPDH,saccharopine dehydrogenase (putative),nucleus|mitochondrion|mitochondrion|lipid particle|membrane|midbody|,biological_process|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.1,0.338,10,0,0,0,0,0,0.922,0,0,-1.4,1.6
ENSMUSG00000025732,FAM195A,"family with sequence similarity 195, member A",cellular_component|,biological_process|,protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000028470,HINT2,histidine triad nucleotide binding protein 2,mitochondrion|mitochondrion|,lipid metabolic process|steroid biosynthetic process|apoptotic process|biological_process|,nucleotide binding|catalytic activity|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.1,0.062,10,0,0,0,0,0,0.922,0,0,-1.6,1.5
ENSMUSG00000060180,MYH13,"myosin, heavy polypeptide 13, skeletal muscle",myosin complex|myofibril|extracellular vesicular exosome|,cellular response to starvation|,nucleotide binding|actin binding|ATP binding|,10,0.1,0.173,10,0,0,0,0,0,0.922,0,0,-1.2,1.7
ENSMUSG00000034853,ACOT11,acyl-CoA thioesterase 11,intracellular|cytoplasm|extracellular vesicular exosome|,fatty acid metabolic process|intracellular signal transduction|,"lipid binding|CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0.1,0.266,10,-0.1,0.181,0,0,0,0.922,0,0,-1,1.8
ENSMUSG00000032875,ARHGEF17,Rho guanine nucleotide exchange factor (GEF) 17,None,actin cytoskeleton organization|regulation of Rho protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,-0.1,0.586,10,0,0,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000042476,ABCB4,"ATP-binding cassette, sub-family B (MDR/TAP), member 4",Golgi membrane|plasma membrane|membrane|integral component of membrane|apical plasma membrane|intercellular canaliculus|,ATP catabolic process|transport|transmembrane transport|,"nucleotide binding|ATP binding|xenobiotic-transporting ATPase activity|hydrolase activity|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,0,0,10,0.1,0.221,0,0,0,0.922,0,0,-1.5,1.4
ENSMUSG00000024978,GPAM,"glycerol-3-phosphate acyltransferase, mitochondrial",mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|plasma membrane|membrane|integral component of membrane|mitochondrial membrane|,lipid metabolic process|fatty acid metabolic process|acyl-CoA metabolic process|triglyceride metabolic process|glycerophospholipid metabolic process|metabolic process|phospholipid biosynthetic process|response to glucose|positive regulation of triglyceride biosynthetic process|response to activity|triglyceride biosynthetic process|cellular response to insulin stimulus|positive regulation of multicellular organism growth|positive regulation of activated T cell proliferation|cellular lipid metabolic process|regulation of cytokine secretion|defense response to virus|fatty acid homeostasis|phospholipid homeostasis|negative regulation of activation-induced cell death of T cells|interleukin-2 secretion|,"glycerol-3-phosphate O-acyltransferase activity|glycerol-3-phosphate O-acyltransferase activity|glycerol-3-phosphate O-acyltransferase activity|O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.2,0.45,10,0,0,0,0,0,0.922,0,0,-1.5,1.5
ENSMUSG00000026014,RAPH1,Ras association (RalGDS/AF-6) and pleckstrin homology domains 1,cell leading edge|,axon extension|,protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000045664,CDC42EP2,CDC42 effector protein (Rho GTPase binding) 2,cytoplasm|cytoskeleton|plasma membrane|microtubule cytoskeleton|membrane|,regulation of cell shape|actin cytoskeleton organization|positive regulation of actin filament polymerization|positive regulation of pseudopodium assembly|positive regulation of Rho GTPase activity|,opioid peptide activity|Rho GTPase activator activity|GTP-Rho binding|,10,0.1,0.416,10,0,0,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000052301,DOC2A,"double C2, alpha",lysosome|synaptic vesicle|membrane|cell junction|cytoplasmic vesicle|neuron projection|synapse|,transport|exocytosis|regulation of calcium ion-dependent exocytosis|regulation of calcium ion-dependent exocytosis|,transporter activity|calcium-dependent phospholipid binding|,10,0.1,0.148,10,-0.6,0.345,0,0,0,0.922,0,0,-2,1
ENSMUSG00000050520,CLDN8,claudin 8,endoplasmic reticulum|plasma membrane|tight junction|membrane|integral component of membrane|basolateral plasma membrane|cell junction|,None,structural molecule activity|protein binding|,10,0,0,10,0.1,0.0499,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000054619,METTL7A1,methyltransferase like 7A1,extracellular vesicular exosome|,biological_process|methylation|,molecular_function|methyltransferase activity|transferase activity|,10,-0.8,1.57,10,0.2,0.166,0,0,0,0.922,0,0,-2,1
ENSMUSG00000041351,RAP1GAP,Rap1 GTPase-activating protein,Golgi apparatus|cytosol|membrane|,regulation of Ras GTPase activity|positive regulation of Rap GTPase activity|regulation of small GTPase mediated signal transduction|,GTPase activator activity|Ras GTPase binding|GTPase regulator activity|protein homodimerization activity|Rap GTPase activator activity|,10,0.1,0.0193,10,0.5,0.487,0,0,0,0.922,0,0,-0.9,1.9
ENSMUSG00000038188,SCARF1,"scavenger receptor class F, member 1",membrane|integral component of membrane|,receptor-mediated endocytosis|cell adhesion|positive regulation of neuron projection development|neuron remodeling|dendrite development|positive regulation of axon regeneration|,scavenger receptor activity|protein binding|low-density lipoprotein particle binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-0.9,2
ENSMUSG00000032198,DOCK6,dedicator of cytokinesis 6,cellular_component|cytoplasm|,small GTPase mediated signal transduction|biological_process|,molecular_function|guanyl-nucleotide exchange factor activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.8
ENSMUSG00000028923,NECAP2,NECAP endocytosis associated 2,intracellular|plasma membrane|membrane|clathrin vesicle coat|cytoplasmic vesicle|,transport|endocytosis|biological_process|protein transport|,molecular_function|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.6,1.4
ENSMUSG00000021913,OGDHL,oxoglutarate dehydrogenase-like,cellular_component|,biological_process|,molecular_function|,10,0.1,0.301,10,0,0,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000023439,GNB3,"guanine nucleotide binding protein (G protein), beta 3",heterotrimeric G-protein complex|neuron projection|cell body|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|,GTPase activity|signal transducer activity|spectrin binding|GTPase binding|,10,0.1,0.174,10,0,0,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000041729,CORO2B,"coronin, actin binding protein, 2B",cytoplasm|cytoskeleton|actin cytoskeleton|membrane|,actin cytoskeleton organization|,actin binding|actin filament binding|,10,-0.2,0.612,10,0.3,0.172,0,0,0,0.922,0,0,-1.5,1.5
ENSMUSG00000039987,PHTF2,putative homeodomain transcription factor 2,nucleus|endoplasmic reticulum|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|,10,0.2,0.356,10,-0.1,0.17,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000032589,BSN,bassoon,cytoplasm|cytoskeleton|extrinsic component of membrane|cell junction|axon|dendrite|neuron projection|neuron projection terminus|synapse|synapse|presynaptic active zone|presynaptic active zone|excitatory synapse|,None,protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.7
ENSMUSG00000034312,IQSEC1,IQ motif and Sec7 domain 1,nucleus|nucleolus|membrane|cell junction|cell junction|intracellular membrane-bounded organelle|,actin cytoskeleton organization|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|,10,0,0,10,-0.4,1.13,0,0,0,0.922,0,0,-1.6,1.4
ENSMUSG00000032890,RIMS3,regulating synaptic membrane exocytosis 3,cell|cell junction|synapse|,transport|neurotransmitter transport|exocytosis|calcium ion-dependent exocytosis|regulation of membrane potential|regulation of synaptic vesicle exocytosis|,ion channel binding|,10,0,0,10,-0.1,0.36,0,0,0,0.922,0,0,-1.6,1.4
ENSMUSG00000026979,PSD4,pleckstrin and Sec7 domain containing 4,plasma membrane|membrane|membrane|cell junction|,neuron differentiation|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|lipid binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000019731,SLC35E1,"solute carrier family 35, member E1",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0,0,10,0.1,0.326,0,0,0,0.922,0,0,-1.3,1.6
ENSMUSG00000019823,MICAL1,"microtubule associated monooxygenase, calponin and LIM domain containing 1",cytoplasm|cytoskeleton|,negative regulation of protein phosphorylation|sulfur oxidation|actin filament depolymerization|actin filament depolymerization|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|oxidation-reduction process|oxidation-reduction process|,"actin binding|actin binding|monooxygenase activity|protein binding|zinc ion binding|3-(3-hydroxyphenyl)propionate hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen|SH3 domain binding|Rab GTPase binding|4-chlorobenzaldehyde oxidase activity|3,5-xylenol methylhydroxylase activity|phenylacetate hydroxylase activity|4-nitrophenol 4-monooxygenase activity|dimethyl sulfide monooxygenase activity|alpha-pinene monooxygenase [NADH] activity|phenanthrene 9,10-monooxygenase activity|1-hydroxy-2-naphthoate hydroxylase activity|toluene 4-monooxygenase activity|xylene monooxygenase activity|dibenzothiophene monooxygenase activity|6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|chlorophenol 4-monooxygenase activity|carbon disulfide oxygenase activity|toluene 2-monooxygenase activity|1-hydroxy-2-oxolimonene 1,2-monooxygenase activity|phenanthrene 1,2-monooxygenase activity|tetrahydrofuran hydroxylase activity|styrene monooxygenase activity|toluene-4-sulfonate monooxygenase activity|toluene-sulfonate methyl-monooxygenase activity|3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|2-hydroxy-phenylacetate hydroxylase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity|phenanthrene 3,4-monooxygenase activity|toluene 3-monooxygenase activity|4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity|limonene monooxygenase activity|2-methylnaphthalene hydroxylase activity|1-methylnaphthalene hydroxylase activity|bisphenol A hydroxylase A activity|salicylate 5-hydroxylase activity|isobutylamine N-hydroxylase activity|branched-chain dodecylbenzene sulfonate monooxygenase activity|3-HSA hydroxylase activity|4-hydroxypyridine-3-hydroxylase activity|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity|6-hydroxynicotinate 3-monooxygenase activity|metal ion binding|tocotrienol omega-hydroxylase activity|FAD binding|thalianol hydroxylase activity|",10,0,0,10,0,0,0,0,0,0.922,0,0,-1.7,1.3
ENSMUSG00000028575,EQTN,"equatorin, sperm acrosome associated",inner acrosomal membrane|acrosomal membrane|outer acrosomal membrane|cell|nucleus|cytoplasm|early endosome|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,acrosome assembly|endocytosis|fusion of sperm to egg plasma membrane|acrosomal vesicle exocytosis|,protein binding|,10,0,0,10,0.1,0.306,0,0,0,0.922,0,0,-1.2,1.8
ENSMUSG00000068742,CRY2,cryptochrome 2 (photolyase-like),intracellular|cell|nucleus|nucleus|cytoplasm|mitochondrion|,"negative regulation of transcription from RNA polymerase II promoter|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein import into nucleus|circadian rhythm|protein-chromophore linkage|lipid storage|negative regulation of phosphoprotein phosphatase activity|response to insulin|circadian regulation of gene expression|circadian regulation of gene expression|glucose homeostasis|regulation of circadian rhythm|negative regulation of circadian rhythm|entrainment of circadian clock by photoperiod|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|rhythmic process|response to stimulus|negative regulation of glucocorticoid receptor signaling pathway|negative regulation of glucocorticoid secretion|",nucleotide binding|transcription regulatory region sequence-specific DNA binding|transcription factor binding transcription factor activity|DNA binding|damaged DNA binding|single-stranded DNA binding|DNA photolyase activity|protein binding|photoreceptor activity|kinase binding|protein kinase binding|phosphatase binding|nuclear hormone receptor binding|ubiquitin binding|FAD binding|,10,-0.1,0.126,10,0,0,0,0,0,0.922,0,0,-1.6,1.5
ENSMUSG00000024600,SLC27A6,"solute carrier family 27 (fatty acid transporter), member 6",endoplasmic reticulum|,long-chain fatty acid metabolic process|,long-chain fatty acid-CoA ligase activity|very long-chain fatty acid-CoA ligase activity|,10,0,0,10,0.1,0.444,0,0,0,0.922,0,0,-1.1,1.8
ENSMUSG00000005973,RCN1,reticulocalbin 1,endoplasmic reticulum|,in utero embryonic development|camera-type eye development|,calcium ion binding|metal ion binding|,10,0.2,0.451,10,0,0,0,0,0,0.922,0,0,-1.3,1.8
ENSMUSG00000050132,SARM1,sterile alpha and HEAT/Armadillo motif containing 1,cytoplasm|mitochondrion|mitochondrion|microtubule|microtubule cytoskeleton|cell junction|dendrite|extrinsic component of mitochondrial outer membrane|cell projection|synapse|,immune system process|signal transduction|nervous system development|response to glucose|cell differentiation|regulation of apoptotic process|innate immune response|regulation of dendrite morphogenesis|regulation of neuron death|,protein binding|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.4,1.6
ENSMUSG00000021314,AMPH,amphiphysin,cell|cytoplasm|cytoskeleton|synaptic vesicle|membrane|cell junction|leading edge membrane|cytoplasmic vesicle|axon terminus|synapse|,learning|synaptic vesicle endocytosis|,protein binding|phospholipid binding|protein C-terminus binding|protein complex binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.1,1.9
ENSMUSG00000024319,VPS52,vacuolar protein sorting 52 (yeast),cellular_component|endosome|Golgi apparatus|membrane|,transport|ectodermal cell differentiation|protein transport|embryonic ectodermal digestive tract development|,molecular_function|,10,0,0,10,-0.9,1.62,0,0,0,0.922,0,0,-2,0.7
ENSMUSG00000031327,CHIC1,cysteine-rich hydrophobic domain 1,cellular_component|plasma membrane|membrane|cytoplasmic vesicle|,biological_process|,molecular_function|,10,0,0,10,0.2,0.428,0,0,0,0.922,0,0,-1.3,1.7
ENSMUSG00000010607,PIGYL,"phosphatidylinositol glycan anchor biosynthesis, class Y-like",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,GPI anchor biosynthetic process|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.6,1.5
ENSMUSG00000041831,SYTL3,synaptotagmin-like 3,membrane|extrinsic component of plasma membrane|,intracellular protein transport|exocytosis|,protein binding|phospholipid binding|calcium-dependent phospholipid binding|zinc ion binding|Rab GTPase binding|neurexin family protein binding|,10,0,0,10,0.1,0.156,0,0,0,0.922,0,0,-1.4,1.6
ENSMUSG00000032092,MPZL2,myelin protein zero-like 2,plasma membrane|membrane|integral component of membrane|,cell adhesion|single organismal cell-cell adhesion|T cell differentiation in thymus|,molecular_function|,10,0,0,10,-1.1,1.38,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000001120,PCBP3,poly(rC) binding protein 3,nucleus|cytoplasm|cytosol|ribonucleoprotein complex|,None,DNA binding|RNA binding|poly(A) RNA binding|,10,-0.4,1.18,10,0,0,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000045625,PIGZ,"phosphatidylinositol glycan anchor biosynthesis, class Z",endoplasmic reticulum|membrane|integral component of membrane|,GPI anchor biosynthetic process|mannosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.4,0.504,10,0,0,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000000811,TXNRD3,thioredoxin reductase 3,nucleus|cytoplasm|endoplasmic reticulum|intracellular membrane-bounded organelle|,glutathione metabolic process|transport|multicellular organismal development|spermatogenesis|cell differentiation|cell redox homeostasis|oxidation-reduction process|,"thioredoxin-disulfide reductase activity|protein binding|electron carrier activity|protein disulfide oxidoreductase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor|flavin adenine dinucleotide binding|NADP binding|",10,0.1,0.336,10,-0.1,0.685,0,0,0,0.922,0,0,-1.6,1.3
ENSMUSG00000076435,ACSF2,acyl-CoA synthetase family member 2,mitochondrion|,lipid metabolic process|fatty acid metabolic process|biological_process|metabolic process|,"nucleotide binding|molecular_function|catalytic activity|acyl-CoA ligase activity|succinate-CoA ligase activity|ATP binding|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity|fatty acid ligase activity|ligase activity|3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity|benzoyl acetate-CoA ligase activity|2,4-dichlorobenzoate-CoA ligase activity|pivalate-CoA ligase activity|cyclopropanecarboxylate-CoA ligase activity|adipate-CoA ligase activity|citronellyl-CoA ligase activity|mentha-1,3-dione-CoA ligase activity|thiophene-2-carboxylate-CoA ligase activity|2,4,4-trimethylpentanoate-CoA ligase activity|cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity|3-hydroxypropionyl-CoA synthetase activity|perillic acid:CoA ligase (ADP-forming) activity|perillic acid:CoA ligase (AMP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity|pristanate-CoA ligase activity|malonyl-CoA synthetase activity|",10,0,0,10,0,0,0,0,0,0.922,0,0,-0.8,2
ENSMUSG00000039914,COQ10A,coenzyme Q10 homolog A (yeast),cellular_component|,biological_process|,molecular_function|,10,0.1,0.154,10,-0.1,0.0371,0,0,0,0.922,0,0,-1.5,1.5
ENSMUSG00000038213,TAPBPL,TAP binding protein-like,cellular_component|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,negative regulation of antigen processing and presentation of peptide antigen via MHC class I|,protein complex binding|,10,0,0,10,0.1,0.117,0,0,0,0.922,0,0,-1.5,1.5
ENSMUSG00000046352,GJB2,"gap junction protein, beta 2",cytoplasm|plasma membrane|gap junction|gap junction|connexon complex|membrane|integral component of membrane|lateral plasma membrane|cell junction|,cell communication|sensory perception of sound|transmembrane transport|,gap junction channel activity|protein binding|,10,-0.1,0.064,10,0.1,0.683,0,0,0,0.922,0,0,-1.4,1.5
ENSMUSG00000039678,TBC1D13,"TBC1 domain family, member 13",cellular_component|,biological_process|regulation of Rab GTPase activity|,GTPase activator activity|Rab GTPase activator activity|protein binding|,10,-0.1,0.0266,10,0,0,0,0,0,0.922,0,0,-1.5,1.5
ENSMUSG00000043865,TAS2R118,"taste receptor, type 2, member 118",endoplasmic reticulum|trans-Golgi network|external side of plasma membrane|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|bitter taste receptor activity|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.5,1.6
ENSMUSG00000040220,GAS8,growth arrest specific 8,cytoplasm|Golgi apparatus|cytoskeleton|microtubule|microtubule|cilium|motile cilium|cell projection|,sperm motility|cellular protein localization|cell motility|,Rab GTPase binding|,10,0,0,10,0.1,0.126,0,0,0,0.922,0,0,-1.4,1.6
ENSMUSG00000035735,DAGLA,"diacylglycerol lipase, alpha",plasma membrane|membrane|integral component of membrane|varicosity|,lipid metabolic process|neuroblast proliferation|lipid catabolic process|arachidonic acid metabolic process|arachidonic acid metabolic process|neurogenesis|neurotransmitter biosynthetic process|neurotransmitter biosynthetic process|diacylglycerol catabolic process|endocannabinoid signaling pathway|,"phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|metal ion binding|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.1,0.259,10,0,0,0,0,0,0.922,0,0,-1.1,1.8
ENSMUSG00000039179,TEKT5,tektin 5,nucleus|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.922,0,0,-1.8,1.2
ENSMUSG00000031200,MTCP1,mature T cell proliferation 1,mitochondrion|mitochondrion|,None,None,10,0.8,1.12,10,0,0,0,0,0,0.922,0,0,-0.6,2
ENSMUSG00000038608,DOCK10,dedicator of cytokinesis 10,membrane|extracellular vesicular exosome|,small GTPase mediated signal transduction|regulation of cell migration|positive regulation of Rho GTPase activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho GTPase binding|,10,0.2,1.06,10,-1.1,1.74,0,0,0,0.922,0,0,-2,0.8
ENSMUSG00000035780,UGT2A3,"UDP glucuronosyltransferase 2 family, polypeptide A3",cellular_component|membrane|integral component of membrane|,metabolic process|cellular glucuronidation|,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,0.1,0.0952,10,-0.1,0.572,0,0,0,0.922,0,0,-1.2,1.7
ENSMUSG00000029580,ACTB,"actin, beta",nuclear chromatin|extracellular space|cytoplasm|cytosol|cytoskeleton|postsynaptic density|membrane|axon|ribonucleoprotein complex|cortical cytoskeleton|NuA4 histone acetyltransferase complex|cytoplasmic ribonucleoprotein granule|protein complex|extracellular vesicular exosome|MLL5-L complex|blood microparticle|,axonogenesis|ATP-dependent chromatin remodeling|,nucleotide binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|protein binding|ATP binding|kinesin binding|protein kinase binding|Tat protein binding|nucleosomal DNA binding|nitric-oxide synthase binding|,9,2.5,106,9,2.9,217,2.8,322,322,1.00E-05,1,1,2.4,3.4
ENSMUSG00000031156,SLC35A2,"solute carrier family 35 (UDP-galactose transporter), member A2",Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,transport|carbohydrate transport|nucleotide-sugar transport|UDP-galactose transmembrane transport|,nucleotide-sugar transmembrane transporter activity|sugar:proton symporter activity|UDP-galactose transmembrane transporter activity|UDP-galactose transmembrane transporter activity|,10,1.6,46,10,1.7,181,1.7,227,227,1.00E-05,1,1,1.4,2.1
ENSMUSG00000021611,TERT,telomerase reverse transcriptase,"chromosome, telomeric region|nucleus|nucleoplasm|chromosome|telomerase holoenzyme complex|cytoplasm|PML body|ribonucleoprotein complex|",RNA-dependent DNA replication|telomere maintenance via telomerase|DNA strand elongation|telomere formation via telomerase|DNA biosynthetic process|replicative senescence|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,DNA binding|telomerase activity|telomerase activity|telomeric template RNA reverse transcriptase activity|RNA-directed DNA polymerase activity|protein binding|transferase activity|nucleotidyltransferase activity|protein homodimerization activity|metal ion binding|telomeric RNA binding|,10,2.3,80.5,10,2.1,125,2.2,205,205,1.00E-05,1,1,1.9,2.7
ENSMUSG00000032306,MPI,mannose phosphate isomerase,cytoplasm|extracellular vesicular exosome|,carbohydrate metabolic process|GDP-mannose biosynthetic process|,mannose-6-phosphate isomerase activity|zinc ion binding|isomerase activity|metal ion binding|,10,1.6,64.4,10,2.2,116,1.8,179,179,1.00E-05,1,1,1.4,2.4
ENSMUSG00000037487,UBR5,ubiquitin protein ligase E3 component n-recognin 5,nucleus|nucleus|cytoplasm|cytoplasm|membrane|,"protein polyubiquitination|DNA repair|cellular response to DNA damage stimulus|positive regulation of protein import into nucleus, translocation|positive regulation of catenin import into nucleus|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|progesterone receptor signaling pathway|progesterone receptor signaling pathway|positive regulation of canonical Wnt signaling pathway|negative regulation of histone H2A K63-linked ubiquitination|negative regulation of double-strand break repair|","RNA binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin-ubiquitin ligase activity|ubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,2.5,54.6,10,2.1,108,2.3,161,161,1.00E-05,1,1,1.8,3
ENSMUSG00000032633,FLCN,folliculin,nucleus|cytoplasm|plasma membrane|midbody|cell-cell contact zone|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|regulation of protein phosphorylation|positive regulation of protein phosphorylation|cell-cell junction assembly|positive regulation of gene expression|negative regulation of gene expression|negative regulation of mitochondrion organization|negative regulation of angiogenesis|hemopoiesis|negative regulation of cell growth|negative regulation of cell migration|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|TOR signaling|regulation of TOR signaling|negative regulation of TOR signaling|positive regulation of TOR signaling|regulation of cytokinesis|negative regulation of Rho protein signal transduction|regulation of histone acetylation|positive regulation of cell adhesion|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of protein kinase B signaling|negative regulation of ERK1 and ERK2 cascade|negative regulation of protein localization to nucleus|negative regulation of cell proliferation involved in kidney development|negative regulation of cellular respiration|negative regulation of mitochondrial DNA metabolic process|negative regulation of muscle tissue development|negative regulation of post-translational protein modification|negative regulation of energy homeostasis|regulation of pro-B cell differentiation|negative regulation of ATP biosynthetic process|positive regulation of intrinsic apoptotic signaling pathway|",protein binding|protein complex binding|,10,1.5,45.7,10,1.4,101,1.5,146,146,1.00E-05,1,1,1.1,1.9
ENSMUSG00000004980,HNRNPA2B1,heterogeneous nuclear ribonucleoprotein A2/B1,nucleus|nucleus|spliceosomal complex|cytoplasm|membrane|virion|viral nucleocapsid|ribonucleoprotein complex|catalytic step 2 spliceosome|,"negative regulation of transcription from RNA polymerase II promoter|mRNA processing|RNA splicing|negative regulation of mRNA splicing, via spliceosome|negative regulation of mRNA splicing, via spliceosome|RNA transport|",nucleotide binding|nucleic acid binding|RNA binding|RNA binding|single-stranded telomeric DNA binding|poly(A) RNA binding|pre-mRNA intronic binding|,10,1.7,45.2,10,1.5,93.9,1.7,139,139,1.00E-05,1,1,1.4,2.1
ENSMUSG00000074622,MAFB,"v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)",nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|segment specification|respiratory gaseous exchange|rhombomere 5 development|rhombomere 6 development|T cell differentiation in thymus|brain segmentation|inner ear morphogenesis|negative regulation of erythrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|thymus development|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|,10,1.3,50.6,10,2.2,85.7,1.4,134,134,1.00E-05,1,1,1.2,2.3
ENSMUSG00000014859,E2F4,E2F transcription factor 4,nucleus|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|,"regulation of transcription involved in G1/S transition of mitotic cell cycle|regulation of transcription involved in G1/S transition of mitotic cell cycle|mitotic cell cycle|epithelial cell development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|cell volume homeostasis|cell cycle|blood circulation|regulation of cell size|organ morphogenesis|regulation of cell proliferation|cilium assembly|regulation of cell cycle|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein domain specific binding|,10,2,64.2,10,1.2,62.7,1.8,124,124,1.00E-05,1,1,1.3,2.3
ENSMUSG00000015961,ADSS,"adenylosuccinate synthetase, non muscle",cytoplasm|plasma membrane|,purine nucleotide biosynthetic process|AMP biosynthetic process|AMP biosynthetic process|GTP catabolic process|aspartate metabolic process|IMP metabolic process|,nucleotide binding|adenylosuccinate synthase activity|adenylosuccinate synthase activity|GTP binding|ligase activity|metal ion binding|,10,1,40,10,1.2,69.8,1.2,109,109,1.00E-05,1,1,0.9,1.7
ENSMUSG00000001525,TUBB5,"tubulin, beta 5 class I",nucleus|nucleus|nuclear envelope lumen|cytoplasm|cytoskeleton|microtubule|microtubule|cytoplasmic ribonucleoprotein granule|protein complex|cell body|tubulin complex|extracellular vesicular exosome|,GTP catabolic process|microtubule-based process|microtubule-based process|cellular process|spindle assembly|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|protein domain specific binding|protein complex binding|GTPase activating protein binding|MHC class I protein binding|,10,1.1,21.6,10,1.5,85.9,1.4,106,106,1.00E-05,1,1,1,2
ENSMUSG00000042308,SETD1A,SET domain containing 1A,nucleus|nucleus|histone methyltransferase complex|Set1C/COMPASS complex|,peptidyl-lysine methylation|stem cell maintenance|methylation|histone H3-K4 methylation|histone H3-K4 methylation|positive regulation of neural precursor cell proliferation|positive regulation of stem cell proliferation|,methyltransferase activity|transferase activity|histone methyltransferase activity (H3-K4 specific)|,10,0.8,21.8,9,1.8,88.3,1.7,103,103,1.00E-05,1,1,1.2,2.2
ENSMUSG00000025134,ALYREF,Aly/REF export factor,nucleus|spliceosomal complex|cytoplasm|,mRNA processing|transport|RNA splicing|mRNA transport|,nucleotide binding|nucleic acid binding|single-stranded DNA binding|RNA binding|,8,2.6,39.3,8,1.5,65.6,2.4,100,100,1.00E-05,1,1,1,3.6
ENSMUSG00000034349,SMC4,structural maintenance of chromosomes 4,condensin complex|nucleus|chromosome|cytoplasm|,cell cycle|mitotic nuclear division|mitotic chromosome condensation|meiotic chromosome condensation|chromosome condensation|meiotic chromosome segregation|chromosome organization|cell division|kinetochore organization|,nucleotide binding|protein binding|ATP binding|protein heterodimerization activity|,10,1.2,23.8,10,1.4,74.2,1.3,97,97,1.00E-05,1,1,1,1.8
ENSMUSG00000022314,RAD21,RAD21 homolog (S. pombe),"nuclear chromosome|chromosome, centromeric region|chromatin|nucleus|chromosome|cohesin complex|membrane|nuclear meiotic cohesin complex|",DNA repair|regulation of transcription from RNA polymerase II promoter|apoptotic process|cellular response to DNA damage stimulus|cell cycle|chromosome segregation|mitotic nuclear division|cell division|protein localization to chromatin|,protein binding|,10,1.4,28.4,10,1.3,68.4,1.4,96.3,96.3,1.00E-05,1,1,1.1,1.9
ENSMUSG00000021240,ABCD4,"ATP-binding cassette, sub-family D (ALD), member 4",endoplasmic reticulum membrane|membrane|integral component of membrane|,transport|cobalamin metabolic process|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,1,20.6,10,1.7,74.6,1.4,92.9,92.9,1.00E-05,1,1,1,2
ENSMUSG00000029752,ASNS,asparagine synthetase,None,asparagine biosynthetic process|glutamine metabolic process|metabolic process|cellular amino acid biosynthetic process|cellular response to glucose starvation|negative regulation of apoptotic process|positive regulation of mitotic cell cycle|,nucleotide binding|asparagine synthase (glutamine-hydrolyzing) activity|ATP binding|ligase activity|protein homodimerization activity|cofactor binding|,10,1,45.9,10,1.8,47.3,1.1,91.4,91.4,1.00E-05,1,1,0.9,1.8
ENSMUSG00000073982,RHOG,"ras homolog gene family, member G",intracellular|plasma membrane|membrane|extracellular vesicular exosome|,"GTP catabolic process|small GTPase mediated signal transduction|Rho protein signal transduction|Rac protein signal transduction|actin cytoskeleton organization|activation of Rac GTPase activity|positive regulation of transcription, DNA-templated|cell chemotaxis|positive regulation of establishment of protein localization to plasma membrane|regulation of ruffle assembly|",nucleotide binding|GTPase activity|protein binding|GTP binding|,10,0.9,37.6,10,1.2,49.9,1.1,85.9,85.9,1.00E-05,1,1,0.7,1.5
ENSMUSG00000022508,BCL6,B cell leukemia/lymphoma 6,intracellular|nucleus|nucleus|replication fork|,"protein import into nucleus, translocation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|cell morphogenesis|negative regulation of cell-matrix adhesion|immune system process|germinal center formation|negative regulation of type 2 immune response|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|inflammatory response|cellular response to DNA damage stimulus|Rho protein signal transduction|spermatogenesis|protein localization|negative regulation of cell proliferation|actin cytoskeleton organization|B cell differentiation|negative regulation of cell growth|positive regulation of B cell proliferation|positive regulation of histone deacetylation|regulation of Rho GTPase activity|negative regulation of mast cell cytokine production|negative regulation of Rho protein signal transduction|type 2 immune response|regulation of cell proliferation|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of memory T cell differentiation|negative regulation of cell differentiation|negative regulation of T-helper 2 cell differentiation|positive regulation of neuron differentiation|negative regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of isotype switching to IgE isotypes|negative regulation of isotype switching to IgE isotypes|erythrocyte development|regulation of inflammatory response|positive regulation of cellular component movement|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|chromatin DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|,10,1.2,49.9,10,0.9,37.8,1.1,84.5,84.5,1.00E-05,1,1,0.8,1.5
ENSMUSG00000031197,VBP1,von Hippel-Lindau binding protein 1,nucleus|cytoplasm|cytoplasm|prefoldin complex|intracellular membrane-bounded organelle|,protein folding|,unfolded protein binding|,10,1.2,47.6,10,1.1,34.3,1.1,81.5,81.5,1.00E-05,1,1,0.9,1.5
ENSMUSG00000039067,PSMD7,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 7",proteasome complex|nucleus|proteasome regulatory particle|membrane|extracellular vesicular exosome|,None,None,10,2.3,40.5,10,1.5,43.9,2,81.3,81.3,1.00E-05,1,1,1.2,3
ENSMUSG00000049932,H2AFX,"H2A histone family, member X","chromosome, telomeric region|chromatin|nucleosome|nuclear chromatin|condensed nuclear chromosome|male germ cell nucleus|XY body|nucleus|nucleus|replication fork|chromosome|site of double-strand break|site of double-strand break|",double-strand break repair via homologous recombination|DNA repair|DNA repair|DNA recombination|cellular response to DNA damage stimulus|cell cycle|meiotic nuclear division|spermatogenesis|,DNA binding|damaged DNA binding|protein binding|enzyme binding|histone binding|protein heterodimerization activity|,9,1.3,38,9,1.5,39.5,1.4,77,77,2.00E-05,1,1,1,1.8
ENSMUSG00000075706,GPX4,glutathione peroxidase 4,nucleus|nucleus|nuclear envelope|cytoplasm|mitochondrion|mitochondrial inner membrane|cytosol|extracellular vesicular exosome|,chromatin organization|glutathione metabolic process|response to oxidative stress|multicellular organismal development|spermatogenesis|hydrogen peroxide catabolic process|regulation of inflammatory response|oxidation-reduction process|,peroxidase activity|glutathione peroxidase activity|glutathione peroxidase activity|selenium binding|oxidoreductase activity|glutathione binding|phospholipid-hydroperoxide glutathione peroxidase activity|,10,1.7,19.8,10,2.1,58.1,1.9,76.5,76.5,2.00E-05,1,1,1.6,3
ENSMUSG00000059743,FDPS,farnesyl diphosphate synthetase,nucleus|cytoplasm|mitochondrion|mitochondrial matrix|peroxisome|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|isoprenoid biosynthetic process|sterol biosynthetic process|farnesyl diphosphate biosynthetic process|positive regulation of cholesterol biosynthetic process|positive regulation of cell growth involved in cardiac muscle cell development|,dimethylallyltranstransferase activity|farnesyltranstransferase activity|geranyltranstransferase activity|transferase activity|poly(A) RNA binding|metal ion binding|,10,0.7,18.3,10,2.2,64.1,1.3,75.3,75.3,5.00E-05,1,1,1.1,2.3
ENSMUSG00000022443,MYH9,"myosin, heavy polypeptide 9, non-muscle",stress fiber|stress fiber|ruffle|immunological synapse|immunological synapse|uropod|uropod|nucleus|cytoplasm|cytoplasm|spindle|actomyosin contractile ring|cytosol|cytoskeleton|plasma membrane|plasma membrane|cell-cell adherens junction|cell cortex|COP9 signalosome|integrin complex|actin cytoskeleton|membrane|myosin complex|myosin II complex|myosin II complex|cortical cytoskeleton|cell leading edge|neuromuscular junction|cleavage furrow|actomyosin|protein complex|extracellular vesicular exosome|myosin II filament|,meiotic spindle organization|cell morphogenesis involved in differentiation|cytokinesis|angiogenesis|in utero embryonic development|establishment of T cell polarity|ATP catabolic process|membrane protein ectodomain proteolysis|cellular component movement|cell adhesion|myoblast fusion|regulation of cell shape|regulation of cell shape|protein transport|single organismal cell-cell adhesion|actin filament-based movement|platelet formation|actomyosin structure organization|actin cytoskeleton reorganization|uropod organization|blood vessel endothelial cell migration|establishment of meiotic spindle localization|,microfilament motor activity|nucleotide binding|motor activity|actin binding|protein binding|calmodulin binding|ATP binding|ATPase activity|actin-dependent ATPase activity|protein homodimerization activity|protein anchor|ADP binding|poly(A) RNA binding|actin filament binding|,10,1,44.4,10,0.9,29.1,1,73.1,73.1,7.00E-05,1,1,0.7,1.3
ENSMUSG00000042275,PELO,pelota homolog (Drosophila),cellular_component|nucleus|cytoplasm|,"cell cycle|cell proliferation|chromosome organization|cell division|nuclear-transcribed mRNA catabolic process, non-stop decay|nuclear-transcribed mRNA catabolic process, no-go decay|RNA surveillance|",molecular_function|nuclease activity|endonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,1.8,22.9,10,2,50.7,1.9,73,73,7.00E-05,1,1,1.2,2.5
ENSMUSG00000061607,MDC1,mediator of DNA damage checkpoint 1,nucleus|chromosome|focal adhesion|,DNA repair|cellular response to DNA damage stimulus|cell cycle|,protein C-terminus binding|FHA domain binding|,10,0.9,13,10,1.7,62.1,1.5,72.1,72.1,7.00E-05,1,1,0.9,2.3
ENSMUSG00000059923,GRB2,growth factor receptor bound protein 2,intracellular|nucleus|cytoplasm|cytoplasm|endosome|Golgi apparatus|plasma membrane|cell-cell junction|COP9 signalosome|COP9 signalosome|vesicle membrane|membrane|protein complex|extracellular vesicular exosome|Grb2-EGFR complex|,Ras protein signal transduction|aging|insulin receptor signaling pathway|fibroblast growth factor receptor signaling pathway|positive regulation of signal transduction|cell differentiation|positive regulation of actin filament polymerization|receptor internalization|signal transduction in response to DNA damage|regulation of MAPK cascade|anatomical structure formation involved in morphogenesis|protein heterooligomerization|branching involved in labyrinthine layer morphogenesis|cellular response to ionizing radiation|positive regulation of reactive oxygen species metabolic process|,phosphotyrosine binding|SH3/SH2 adaptor activity|epidermal growth factor receptor binding|neurotrophin TRKA receptor binding|protein binding|SH3 domain binding|protein kinase binding|protein phosphatase binding|protein domain specific binding|protein domain specific binding|identical protein binding|insulin receptor substrate binding|poly(A) RNA binding|ephrin receptor binding|ephrin receptor binding|phosphoprotein binding|,9,1,23.4,8,1.4,48.1,1.1,70.9,70.9,7.00E-05,1,1,0.8,1.7
ENSMUSG00000030744,RPS3,ribosomal protein S3,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|ribosome|endomembrane system|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|dendrite|ribonucleoprotein complex|ruffle membrane|extracellular vesicular exosome|NF-kappaB complex|,"DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|cytoplasmic translation|DNA repair|translation|negative regulation of NF-kappaB transcription factor activity|regulation of apoptotic process|negative regulation of DNA repair|positive regulation of NF-kappaB transcription factor activity|nucleic acid phosphodiester bond hydrolysis|positive regulation of DNA N-glycosylase activity|positive regulation of apoptotic signaling pathway|",damaged DNA binding|RNA binding|mRNA binding|structural constituent of ribosome|structural constituent of ribosome|DNA-(apurinic or apyrimidinic site) lyase activity|DNA-(apurinic or apyrimidinic site) lyase activity|endonuclease activity|enzyme binding|protein kinase binding|poly(A) RNA binding|protein kinase A binding|NF-kappaB binding|,6,1.4,19.2,8,1.6,51.5,1.5,70,70,7.00E-05,1,1,1.1,2.3
ENSMUSG00000026728,VIM,vimentin,cytoplasm|cytoplasm|peroxisome|cytosol|cytoskeleton|intermediate filament|intermediate filament|plasma membrane|plasma membrane|axon|cell leading edge|cell projection|cell projection|neuron projection|cell body|type III intermediate filament|intermediate filament cytoskeleton|perinuclear region of cytoplasm|extracellular vesicular exosome|,positive regulation of gene expression|negative regulation of neuron projection development|astrocyte development|intermediate filament-based process|intermediate filament organization|regulation of axonogenesis|Bergmann glial cell differentiation|positive regulation of glial cell proliferation|SMAD protein signal transduction|lens fiber cell development|regulation of Schwann cell migration|,glycoprotein binding|double-stranded RNA binding|structural molecule activity|structural constituent of cytoskeleton|structural constituent of eye lens|protein binding|protein C-terminus binding|kinase binding|protein kinase binding|identical protein binding|protein phosphatase 2A binding|scaffold protein binding|,10,0.7,28.1,10,0.9,42.9,0.9,70,70,7.00E-05,1,1,0.7,1.2
ENSMUSG00000024613,TCOF1,"Treacher Collins Franceschetti syndrome 1, homolog",nucleus|nucleolus|cytoplasm|,transport|transcription of nuclear large rRNA transcript from RNA polymerase I promoter|,poly(A) RNA binding|,10,2.2,15.2,10,1.7,53,1.9,66.7,66.7,0.0001,1,1,1.5,3.4
ENSMUSG00000020413,HUS1,Hus1 homolog (S. pombe),nucleus|nucleolus|cytoplasm|checkpoint clamp complex|,DNA damage checkpoint|DNA damage checkpoint|double-strand break repair via homologous recombination|regulation of protein phosphorylation|DNA repair|protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|mitotic cell cycle checkpoint|negative regulation of DNA replication|response to UV|response to UV|embryo development|cellular response to ionizing radiation|,None,10,0.9,11.5,10,1.6,57.5,1.4,66.1,66.1,0.00011,1,1,0.9,2.2
ENSMUSG00000000148,BRAT1,BRCA1-associated ATM activator 1,nucleus|membrane|,response to ionizing radiation|,None,10,1.4,26.1,10,1.8,40.2,1.5,65.6,65.6,0.00013,1,1,0.9,2.1
ENSMUSG00000094624,GM4836,predicted gene 4836,cellular_component|,biological_process|,molecular_function|,6,1.2,17,5,1.4,49,1.3,65.3,65.3,0.00014,1,1,1,1.9
ENSMUSG00000021048,MTHFD1,"methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase",cytoplasm|mitochondrion|cytosol|membrane|extracellular vesicular exosome|,histidine biosynthetic process|purine nucleotide biosynthetic process|one-carbon metabolic process|metabolic process|cellular amino acid biosynthetic process|methionine biosynthetic process|folic acid-containing compound biosynthetic process|oxidation-reduction process|,nucleotide binding|catalytic activity|formate-tetrahydrofolate ligase activity|methenyltetrahydrofolate cyclohydrolase activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|ATP binding|oxidoreductase activity|hydrolase activity|ligase activity|,10,1.2,22.8,10,1.7,41.9,1.4,63.6,63.6,0.00017,1,1,0.9,2
ENSMUSG00000070348,CCND1,cyclin D1,cyclin-dependent protein kinase holoenzyme complex|cyclin-dependent protein kinase holoenzyme complex|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|tight junction|membrane|transcriptional repressor complex|,"regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|re-entry into mitotic cell cycle|positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|cellular response to DNA damage stimulus|cell cycle|lactation|lactation|positive regulation of cell proliferation|response to organonitrogen compound|positive regulation of G2/M transition of mitotic cell cycle|Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of epithelial cell differentiation|endoplasmic reticulum unfolded protein response|mitotic G1 DNA damage checkpoint|Leydig cell differentiation|mammary gland epithelial cell proliferation|positive regulation of mammary gland epithelial cell proliferation|fat cell differentiation|positive regulation of cyclin-dependent protein serine/threonine kinase activity|regulation of protein kinase activity|cell division|regulation of cell cycle|canonical Wnt signaling pathway|mammary gland alveolus development|mammary gland alveolus development|response to UV-A|negative regulation of cell cycle arrest|cellular response to organic substance|regulation of G1/S transition of mitotic cell cycle|",transcription corepressor activity|protein kinase activity|protein binding|transcription factor binding|kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|enzyme binding|protein kinase binding|protein kinase binding|protein complex binding|histone deacetylase binding|proline-rich region binding|,9,1.7,31.5,10,1,33.9,1.1,61.3,61.3,0.00026,1,1,0.9,1.9
ENSMUSG00000020708,PSMC5,"protease (prosome, macropain) 26S subunit, ATPase 5",proteasome complex|nucleus|holo TFIIH complex|cytoplasm|proteasome regulatory particle|membrane|inclusion body|proteasome accessory complex|cytoplasmic vesicle|nuclear proteasome complex|cytosolic proteasome complex|extracellular vesicular exosome|blood microparticle|,"ATP catabolic process|proteolysis|protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of transcription, DNA-templated|positive regulation of inclusion body assembly|",nucleotide binding|receptor binding|protein binding|ATP binding|transcription factor binding|transcription factor binding|peptidase activity|hydrolase activity|ATPase activity|TBP-class protein binding|thyrotropin-releasing hormone receptor binding|,10,0.7,15.3,10,1.2,48.5,0.9,61.1,61.1,0.00026,1,1,0.7,1.4
ENSMUSG00000020048,HSP90B1,"heat shock protein 90, beta (Grp94), member 1",nucleus|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum membrane|smooth endoplasmic reticulum|cytosol|plasma membrane|membrane|midbody|perinuclear region of cytoplasm|extracellular vesicular exosome|,response to hypoxia|protein folding|response to stress|ER-associated ubiquitin-dependent protein catabolic process|actin rod assembly|negative regulation of apoptotic process|regulation of phosphoprotein phosphatase activity|cellular response to ATP|,nucleotide binding|RNA binding|protein binding|ATP binding|protein phosphatase binding|virion binding|low-density lipoprotein particle receptor binding|unfolded protein binding|,10,1.4,19.3,10,1.1,41.9,1.4,60.7,60.7,0.00027,1,1,1,1.8
ENSMUSG00000024844,BANF1,barrier to autointegration factor 1,nucleus|chromosome|cytoplasm|extracellular vesicular exosome|,DNA integration|establishment of integrated proviral latency|,DNA binding|DNA binding|,9,1.6,17.3,9,1.3,44.8,1.4,60.6,60.6,0.00027,1,1,0.9,2
ENSMUSG00000005687,BCAS2,breast carcinoma amplified sequence 2,nucleus|spliceosomal complex|cell junction|,mRNA processing|biological_process|RNA splicing|,molecular_function|,10,1.9,25.1,10,1.3,37.4,1.7,60.1,60.1,0.00028,1,1,1,2.4
ENSMUSG00000036202,RIF1,Rap1 interacting factor 1 homolog (yeast),"chromosome, telomeric region|female pronucleus|male pronucleus|nucleus|nucleus|chromosome|nucleolus|cytoplasm|cytoskeleton|plasma membrane|",cellular response to DNA damage stimulus|cell cycle|stem cell maintenance|,protein binding|,10,0.8,7.49,10,1.2,51.8,1.1,58.1,58.1,0.00039,1,1,0.8,1.6
ENSMUSG00000000290,ITGB2,integrin beta 2,plasma membrane|integrin complex|cell surface|cell surface|membrane|membrane|integral component of membrane|receptor complex|membrane raft|extracellular vesicular exosome|,leukocyte migration involved in inflammatory response|cell adhesion|cell adhesion|leukocyte cell-cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|multicellular organismal development|single organismal cell-cell adhesion|single organismal cell-cell adhesion|natural killer cell activation|neutrophil chemotaxis|neutrophil chemotaxis|endothelial cell migration|cellular extravasation|cellular extravasation|positive regulation of nitric oxide biosynthetic process|positive regulation of angiogenesis|regulation of peptidyl-tyrosine phosphorylation|activated T cell proliferation|positive regulation of NF-kappaB transcription factor activity|,glycoprotein binding|receptor activity|protein binding|protein kinase binding|protein complex binding|metal ion binding|protein heterodimerization activity|cell adhesion molecule binding|,10,0.7,23.9,10,1,35,0.8,57.4,57.4,0.00046,1,1,0.7,1.3
ENSMUSG00000031754,NUDT21,nudix (nucleoside diphosphate linked moiety X)-type motif 21,nucleus|centrosome|mRNA cleavage factor complex|paraspeckles|,mRNA polyadenylation|mRNA cleavage|mRNA processing|protein tetramerization|,RNA binding|mRNA binding|hydrolase activity|AU-rich element binding|protein homodimerization activity|histone deacetylase binding|poly(A) RNA binding|,10,0.9,29,10,1.2,29.1,1.1,56.9,56.9,0.00049,1,1,0.8,1.5
ENSMUSG00000052293,TAF9,"TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor",PCAF complex|nucleus|transcription factor TFIID complex|STAGA complex|transcription factor TFTC complex|pre-snoRNP complex|MLL1 complex|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|positive regulation of cell growth|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|histone H3 acetylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein stabilization|positive regulation of response to cytokine stimulus|response to interleukin-1|",p53 binding|DNA binding|DNA binding|transcription coactivator activity|histone acetyltransferase activity|activating transcription factor binding|transcription regulatory region DNA binding|protein heterodimerization activity|C2H2 zinc finger domain binding|,10,1,20,10,1.3,37.9,1.2,56.6,56.6,0.00053,1,1,0.8,1.6
ENSMUSG00000020184,MDM2,transformed mouse 3T3 cell double minute 2,nucleus|nucleus|nucleoplasm|nucleolus|nucleolus|cytoplasm|cytoplasm|cytosol|plasma membrane|nuclear body|protein complex|synapse|,"negative regulation of transcription from RNA polymerase II promoter|protein complex assembly|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|traversing start control point of mitotic cell cycle|positive regulation of gene expression|negative regulation of gene expression|negative regulation of protein processing|protein ubiquitination|protein ubiquitination|peptidyl-lysine modification|protein catabolic process|protein destabilization|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|protein localization to nucleus|regulation of protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of DNA damage response, signal transduction by p53 class mediator|establishment of protein localization|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of mitotic cell cycle|positive regulation of protein export from nucleus|negative regulation of cell cycle arrest|","p53 binding|p53 binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|enzyme binding|ubiquitin protein ligase binding|identical protein binding|peroxisome proliferator activated receptor binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|scaffold protein binding|",8,1.2,28.2,8,1.2,28.6,1.2,56.4,56.4,0.00054,1,1,0.9,1.7
ENSMUSG00000021958,PINX1,"PIN2/TERF1 interacting, telomerase inhibitor 1","nuclear chromosome|chromosome, centromeric region|kinetochore|chromosome, telomeric region|nucleus|chromosome|nucleolus|nucleolus|spindle|",telomere maintenance via telomerase|mitotic metaphase plate congression|,nucleic acid binding|protein binding|telomeric RNA binding|,10,0.9,21.5,10,1.7,35.6,0.9,56,56,0.00056,1,1,0.7,1.7
ENSMUSG00000067567,HDAC8,histone deacetylase 8,histone deacetylase complex|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|sister chromatid cohesion|chromatin modification|histone deacetylation|regulation of cohesin localization to chromatin|",histone deacetylase activity|transcription factor binding|hydrolase activity|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|histone deacetylase activity (H4-K16 specific)|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,0.8,21.7,10,1,34.5,0.9,55.6,55.6,0.00059,1,1,0.7,1.2
ENSMUSG00000022967,IFNAR1,interferon (alpha and beta) receptor 1,membrane|integral component of membrane|,cytokine-mediated signaling pathway|positive regulation of interferon-gamma production|T cell activation|type I interferon biosynthetic process|positive regulation of interleukin-1 beta secretion|defense response to virus|,phosphoribosylamine-glycine ligase activity|interferon receptor activity|,9,0.6,18.1,10,0.8,38,0.8,55,55,0.00065,1,1,0.6,1.1
ENSMUSG00000051768,XRCC1,X-ray repair complementing defective repair in Chinese hamster cells 1,nucleus|nucleus|,single strand break repair|DNA repair|base-excision repair|base-excision repair|cellular response to DNA damage stimulus|hippocampus development|,damaged DNA binding|,9,1.1,12.4,9,1,42.1,1.1,54,54,0.00076,1,1,0.8,1.7
ENSMUSG00000026812,TSC1,tuberous sclerosis 1,cytoplasm|cytoplasm|cytosol|cytoskeleton|actin filament|cell cortex|membrane|lamellipodium|growth cone|TSC1-TSC2 complex|TSC1-TSC2 complex|intracellular membrane-bounded organelle|protein complex|,kidney development|neural tube closure|regulation of cell-matrix adhesion|rRNA export from nucleus|regulation of translation|potassium ion transport|potassium ion transport|cell-matrix adhesion|nervous system development|negative regulation of cell proliferation|negative regulation of cell proliferation|embryo development|negative regulation of translation|hippocampus development|cerebral cortex development|cell projection organization|negative regulation of TOR signaling|negative regulation of TOR signaling|regulation of Ras GTPase activity|activation of Rho GTPase activity|response to insulin|regulation of actin cytoskeleton organization|regulation of actin cytoskeleton organization|myelination|regulation of phosphoprotein phosphatase activity|negative regulation of cell size|negative regulation of cell size|regulation of protein kinase activity|negative regulation of insulin receptor signaling pathway|synapse organization|protein stabilization|protein heterooligomerization|regulation of stress fiber assembly|regulation of cell cycle|regulation of focal adhesion assembly|positive regulation of focal adhesion assembly|cardiac muscle cell differentiation|,protein binding|GTPase regulator activity|GTPase regulator activity|GTPase activating protein binding|protein N-terminus binding|protein N-terminus binding|chaperone binding|,10,1.8,20,10,1.7,33.6,1.7,53,53,0.0009,1,1,1.2,2.5
ENSMUSG00000021709,ERBB2IP,Erbb2 interacting protein,intracellular|nucleus|cytoplasm|plasma membrane|membrane|basolateral plasma membrane|cell junction|hemidesmosome|,protein targeting|,integrin binding|protein binding|,10,0.9,34.1,10,0.9,19.2,0.9,52.8,52.8,0.00095,1,1,0.7,1.3
ENSMUSG00000025337,SBDS,Shwachman-Bodian-Diamond syndrome homolog (human),spindle pole|nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|cytoskeleton|,inner cell mass cell proliferation|rRNA processing|rRNA processing|cell proliferation|bone mineralization|leukocyte chemotaxis|ribosome biogenesis|mature ribosome assembly|ribosomal large subunit biogenesis|mitotic spindle stabilization|bone marrow development|,RNA binding|microtubule binding|rRNA binding|ribosome binding|poly(A) RNA binding|,9,0.2,0.708,9,1.6,55.7,1.6,52.8,52.8,0.00095,1,1,1.1,2.8
ENSMUSG00000002102,PSMC3,"proteasome (prosome, macropain) 26S subunit, ATPase 3",proteasome complex|cytoplasmic mRNA processing body|nucleus|cytoplasm|membrane|proteasome accessory complex|perinuclear region of cytoplasm|,blastocyst development|protein catabolic process|,nucleotide binding|ATP binding|hydrolase activity|,9,1,26.9,9,1.1,25.6,1,52.1,52.1,0.00102,1,1,0.7,1.5
ENSMUSG00000031922,CEP57,centrosomal protein 57,intracellular|cell|nucleus|nucleus|cytoplasm|cytoplasm|Golgi apparatus|centrosome|centrosome|cytoskeleton|microtubule|microtubule|microtubule cytoskeleton|,"protein import into nucleus, translocation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|microtubule anchoring|protein homooligomerization|",protein binding|microtubule binding|fibroblast growth factor binding|fibroblast growth factor binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|gamma-tubulin binding|,8,0.9,7.09,9,1.5,46.4,1.5,51.4,51.4,0.00115,1,1,1,2.6
ENSMUSG00000000282,MNT,max binding protein,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell aging|regulation of cell cycle|negative regulation of apoptotic signaling pathway|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|protein dimerization activity|,10,0.9,24.6,10,0.7,26.4,0.8,50.2,50.2,0.00143,1,1,0.6,1.3
ENSMUSG00000059436,MAX,Max protein,nucleus|cytoplasm|PML body|dendrite|cell projection|MLL1 complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|protein complex assembly|negative regulation of gene expression|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein complex binding|protein homodimerization activity|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|,10,1,27.2,10,2.3,29.1,1.4,49.8,49.8,0.00152,1,1,1.2,2.8
ENSMUSG00000021116,EIF2S1,"eukaryotic translation initiation factor 2, subunit 1 alpha",nucleus|cytoplasm|eukaryotic translation initiation factor 2 complex|eukaryotic translation initiation factor 2B complex|cytoplasmic stress granule|membrane|extracellular vesicular exosome|,translation|translation|translational initiation|regulation of translation|regulation of translational initiation in response to stress|protein autophosphorylation|,RNA binding|translation initiation factor activity|protein binding|ribosome binding|poly(A) RNA binding|,9,2,17.9,9,1.5,33.2,1.8,49.5,49.5,0.00158,1,1,1.1,2.8
ENSMUSG00000028684,UROD,uroporphyrinogen decarboxylase,cytoplasm|cytosol|cytosol|,porphyrin-containing compound biosynthetic process|heme biosynthetic process|heme metabolic process|uroporphyrinogen III metabolic process|,uroporphyrinogen decarboxylase activity|uroporphyrinogen decarboxylase activity|uroporphyrinogen decarboxylase activity|ferrous iron binding|lyase activity|carboxy-lyase activity|,10,0.9,22.3,10,2,30.7,1.1,49.2,49.2,0.00165,1,1,0.9,2.3
ENSMUSG00000005566,TRIM28,tripartite motif-containing 28,chromatin|intracellular|nucleus|nucleus|nucleoplasm|nuclear euchromatin|nuclear heterochromatin|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|epithelial to mesenchymal transition|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|embryo implantation|protein ubiquitination|protein sumoylation|positive regulation of transcription factor import into nucleus|DNA methylation involved in embryo development|innate immune response|positive regulation of DNA repair|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|protein autophosphorylation|protein oligomerization|convergent extension involved in axis elongation|embryonic placenta morphogenesis|negative regulation of DNA demethylation|negative regulation of viral release from host cell|regulation of genetic imprinting|","DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription corepressor activity|protein kinase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|Krueppel-associated box domain binding|sequence-specific DNA binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|chromo shadow domain binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,-0.5,15.8,9,-1.9,35.8,-0.6,48.8,-48.8,0.00177,1,1,-1.8,-0.5
ENSMUSG00000021178,PSMC1,"protease (prosome, macropain) 26S subunit, ATPase 1",proteasome complex|nucleus|cytoplasm|proteasome regulatory particle|membrane|proteasome accessory complex|,protein catabolic process|,nucleotide binding|ATP binding|hydrolase activity|TBP-class protein binding|poly(A) RNA binding|,10,0.8,14.4,10,1.6,36.5,0.8,48.7,48.7,0.00179,1,1,0.6,1.8
ENSMUSG00000045092,S1PR1,sphingosine-1-phosphate receptor 1,endosome|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|intrinsic component of plasma membrane|,angiogenesis|blood vessel maturation|cardiac muscle tissue growth involved in heart morphogenesis|sphingosine-1-phosphate signaling pathway|sphingosine-1-phosphate signaling pathway|chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|brain development|positive regulation of cell proliferation|cell migration|lamellipodium assembly|regulation of cell adhesion|positive regulation of cell migration|regulation of bone mineralization|actin cytoskeleton reorganization|positive regulation of Ras GTPase activity|regulation of bone resorption|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle cell proliferation|positive regulation of positive chemotaxis|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|negative regulation of stress fiber assembly|heart trabecula morphogenesis|T cell migration|,G-protein coupled receptor binding|signal transducer activity|G-protein coupled receptor activity|sphingosine-1-phosphate receptor activity|sphingosine-1-phosphate receptor activity|sphingolipid binding|,10,-0.8,13.6,10,-1.7,36.4,-1,46.5,-46.5,0.00244,0,1,-2.5,-0.6
ENSMUSG00000011752,PGAM1,phosphoglycerate mutase 1,nucleus|cytoplasm|cytosol|membrane|extracellular vesicular exosome|,glycolytic process|regulation of glycolytic process|metabolic process|regulation of pentose-phosphate shunt|respiratory burst|,"catalytic activity|bisphosphoglycerate mutase activity|bisphosphoglycerate 2-phosphatase activity|phosphoglycerate mutase activity|phosphoglycerate mutase activity|hydrolase activity|isomerase activity|intramolecular transferase activity, phosphotransferases|protein kinase binding|",9,2.2,43.6,9,1,5.75,2.1,45.7,45.7,0.0026,0,1,1.3,3.4
ENSMUSG00000002870,MCM2,minichromosome maintenance deficient 2 mitotin (S. cerevisiae),chromatin|nucleus|nucleus|nuclear origin of replication recognition complex|cytoplasm|microtubule cytoskeleton|MCM complex|,DNA replication|DNA unwinding involved in DNA replication|DNA replication initiation|DNA replication initiation|nucleosome assembly|cell cycle|cellular response to interleukin-4|,nucleotide binding|DNA binding|DNA helicase activity|DNA replication origin binding|helicase activity|ATP binding|hydrolase activity|histone binding|metal ion binding|,10,1,9.43,10,1.5,36.6,1.2,45.2,45.2,0.00274,0,1,0.7,2.1
ENSMUSG00000035842,DDX11,DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11,nuclear chromatin|spindle pole|nucleus|nucleus|midbody|,nucleobase-containing compound metabolic process|ATP catabolic process|cell cycle|sister chromatid cohesion|,"nucleotide binding|nucleic acid binding|DNA binding|RNA binding|ATP-dependent DNA helicase activity|helicase activity|ATP binding|ATP-dependent helicase activity|DNA-dependent ATPase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.9,17.9,10,1.3,26.7,0.9,43.8,43.8,0.00308,0,1,0.6,1.5
ENSMUSG00000005442,CIC,capicua homolog (Drosophila),nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|lung alveolus development|lung alveolus development|",DNA binding|chromatin binding|protein binding|,10,-0.9,15,10,-0.9,28.6,-0.9,43.2,-43.2,0.00325,0,1,-1.3,-0.6
ENSMUSG00000058301,UPF1,UPF1 regulator of nonsense transcripts homolog (yeast),chromatin|nucleus|cytoplasm|exon-exon junction complex|supraspliceosomal complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|nuclear-transcribed mRNA catabolic process|ATP catabolic process|DNA replication|DNA repair|regulation of translational termination|dosage compensation by inactivation of X chromosome|histone mRNA catabolic process|",nucleotide binding|DNA binding|chromatin binding|RNA binding|ATP-dependent RNA helicase activity|helicase activity|ATP binding|zinc ion binding|hydrolase activity|poly(A) RNA binding|metal ion binding|,9,1.1,15.7,10,1.4,27.6,1.3,42.5,42.5,0.00341,0,1,0.9,1.9
ENSMUSG00000022248,RAD1,RAD1 homolog (S. pombe),nucleus|intracellular membrane-bounded organelle|,DNA damage checkpoint|DNA repair|cellular response to DNA damage stimulus|cellular response to ionizing radiation|nucleic acid phosphodiester bond hydrolysis|,nuclease activity|exonuclease activity|3'-5' exonuclease activity|exodeoxyribonuclease III activity|hydrolase activity|,8,0.3,1.78,10,1.6,44.1,1.3,42.4,42.4,0.00345,0,1,0.7,2.3
ENSMUSG00000027323,RAD51,RAD51 homolog,nuclear chromosome|condensed chromosome|condensed nuclear chromosome|synaptonemal complex|lateral element|nucleus|nucleus|nucleolus|cytoplasm|mitochondrion|cytoskeleton|PML body|perinuclear region of cytoplasm|,double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|ATP catabolic process|DNA metabolic process|DNA unwinding involved in DNA replication|DNA repair|DNA recombination|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|meiotic nuclear division|reciprocal meiotic recombination|regulation of double-strand break repair via homologous recombination|positive regulation of DNA ligation|protein homooligomerization|cellular response to ionizing radiation|cellular response to camptothecin|,nucleotide binding|DNA binding|damaged DNA binding|double-stranded DNA binding|single-stranded DNA binding|protein binding|ATP binding|protein C-terminus binding|DNA-dependent ATPase activity|identical protein binding|single-stranded DNA-dependent ATPase activity|DNA polymerase binding|,9,1.9,10.1,8,1.9,32.4,1.9,42.2,42.2,0.0035,0,1,1.3,3
ENSMUSG00000025410,DCTN2,dynactin 2,kinetochore|cell|cytoplasm|cytoplasm|centrosome|centrosome|cytoskeleton|dynactin complex|dynactin complex|microtubule|membrane|dynein complex|growth cone|vesicle|extracellular vesicular exosome|,microtubule-based process|mitotic spindle organization|mitotic spindle organization|mitotic nuclear division|cell proliferation|melanosome transport|,motor activity|protein binding|spectrin binding|,10,1.3,26.4,10,0.9,16.5,1.1,41.4,41.4,0.00371,0,1,0.8,1.6
ENSMUSG00000006998,PSMD2,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 2",proteasome complex|proteasome regulatory particle|membrane|proteasome accessory complex|extracellular vesicular exosome|,regulation of protein catabolic process|,protein binding|enzyme regulator activity|,10,0.9,16.6,10,1.9,28.3,1,41.4,41.4,0.00371,0,1,0.8,2.4
ENSMUSG00000006398,CDC20,cell division cycle 20,nucleus|anaphase-promoting complex|cytoplasm|centrosome|cytoskeleton|protein complex|perinuclear region of cytoplasm|,cell cycle|mitotic nuclear division|nervous system development|positive regulation of cell proliferation|cell differentiation|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|positive regulation of synaptic plasticity|regulation of meiosis|regulation of dendrite development|cell division|activation of anaphase-promoting complex activity|positive regulation of synapse maturation|,protein binding|protein C-terminus binding|enzyme binding|,8,1.6,6.59,9,1.7,34.7,1.7,40.9,40.9,0.00381,0,1,1.2,2.7
ENSMUSG00000042029,NCAPG2,"non-SMC condensin II complex, subunit G2",nucleus|membrane|,inner cell mass cell proliferation|cell cycle|mitotic nuclear division|chromosome condensation|cell division|,protein binding|methylated histone binding|,10,2,29.3,10,1.3,12.9,1.9,40.5,40.5,0.00401,0,1,1.2,3.1
ENSMUSG00000024742,FEN1,flap structure specific endonuclease 1,nucleus|nucleus|nucleolus|mitochondrion|membrane|,"DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|DNA replication|DNA repair|cellular response to DNA damage stimulus|memory|DNA replication, removal of RNA primer|nucleic acid phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, endonucleolytic|","magnesium ion binding|DNA binding|DNA binding|catalytic activity|nuclease activity|endonuclease activity|RNA-DNA hybrid ribonuclease activity|exonuclease activity|5'-3' exonuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|5'-flap endonuclease activity|manganese ion binding|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|flap endonuclease activity|",10,1.6,8.46,10,1.4,32.4,1.5,40.3,40.3,0.00409,0,1,0.9,2.4
ENSMUSG00000025159,MMS19,MMS19 (MET18 S. cerevisiae),nucleus|cytoplasm|spindle|cytoskeleton|membrane|MMXD complex|CIA complex|,"DNA metabolic process|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|chromosome segregation|iron-sulfur cluster assembly|positive regulation of transcription, DNA-templated|",transcription coactivator activity|estrogen receptor binding|,10,1.1,14.6,10,2.1,29.3,2,40.3,40.3,0.00409,0,1,1,2.9
ENSMUSG00000001833,7-Sep,septin 7,"chromosome, centromeric region|kinetochore|stress fiber|nucleus|chromosome|nucleolus|cytoplasm|cytoskeleton|plasma membrane|cilium|cell cortex|actin cytoskeleton|microtubule cytoskeleton|membrane|septin complex|cell projection|axon terminus|synapse|extracellular vesicular exosome|",cell cycle|mitotic nuclear division|protein heterooligomerization|cell division|,nucleotide binding|protein binding|GTP binding|identical protein binding|,10,-0.8,2.57,10,1.3,41.8,1.3,40.2,40.2,0.00412,0,1,0.8,2
ENSMUSG00000020914,TOP2A,topoisomerase (DNA) II alpha,nuclear chromosome|condensed chromosome|nucleus|nucleus|nucleoplasm|nucleolus|nucleolus|centriole|DNA topoisomerase complex (ATP-hydrolyzing)|DNA topoisomerase complex (ATP-hydrolyzing)|protein complex|,resolution of meiotic recombination intermediates|sister chromatid segregation|hematopoietic progenitor cell differentiation|ATP catabolic process|ATP catabolic process|DNA metabolic process|DNA topological change|DNA topological change|DNA ligation|DNA unwinding involved in DNA replication|mitotic recombination|cellular response to DNA damage stimulus|chromosome segregation|chromosome segregation|chromosome segregation|chromosome condensation|apoptotic chromosome condensation|apoptotic chromosome condensation|embryonic cleavage|positive regulation of apoptotic process|mitotic DNA integrity checkpoint|positive regulation of viral genome replication|positive regulation of single stranded viral RNA replication via double stranded DNA intermediate|positive regulation of transcription from RNA polymerase II promoter|,"nucleotide binding|magnesium ion binding|DNA binding|chromatin binding|DNA topoisomerase activity|DNA topoisomerase type II (ATP-hydrolyzing) activity|DNA topoisomerase type II (ATP-hydrolyzing) activity|DNA topoisomerase type II (ATP-hydrolyzing) activity|protein kinase C binding|ATP binding|protein C-terminus binding|DNA-dependent ATPase activity|drug binding|DNA binding, bending|isomerase activity|enzyme binding|protein homodimerization activity|histone deacetylase binding|ubiquitin binding|sequence-specific DNA binding|structure-specific DNA binding|poly(A) RNA binding|metal ion binding|protein heterodimerization activity|",9,1.1,22.7,10,1.3,18.4,1.2,40.2,40.2,0.00412,0,1,0.8,1.8
ENSMUSG00000038943,PRC1,protein regulator of cytokinesis 1,nucleus|cytoplasm|spindle|cytoskeleton|microtubule|plasma membrane|microtubule cytoskeleton|,microtubule cytoskeleton organization|cytokinesis|cell cycle|cell division|,microtubule binding|protein kinase binding|identical protein binding|,10,1.2,30.9,10,0.7,10.2,1.1,40.1,40.1,0.00413,0,1,0.8,1.6
ENSMUSG00000029363,RFC5,replication factor C (activator 1) 5,nucleus|DNA replication factor C complex|,DNA replication|,nucleotide binding|DNA binding|ATP binding|,10,1.3,22.2,10,2.2,22.3,2.1,40,40,0.00416,0,1,1.2,3.3
ENSMUSG00000001755,COASY,Coenzyme A synthase,nucleus|cytoplasm|mitochondrion|mitochondrial matrix|extracellular vesicular exosome|,metabolic process|biosynthetic process|coenzyme A biosynthetic process|coenzyme A biosynthetic process|coenzyme A biosynthetic process|phosphorylation|,nucleotide binding|catalytic activity|dephospho-CoA kinase activity|dephospho-CoA kinase activity|dephospho-CoA kinase activity|pantetheine-phosphate adenylyltransferase activity|pantetheine-phosphate adenylyltransferase activity|pantetheine-phosphate adenylyltransferase activity|pantetheine-phosphate adenylyltransferase activity|ATP binding|kinase activity|transferase activity|nucleotidyltransferase activity|,10,1.9,14.3,10,1.8,26.1,1.8,39.9,39.9,0.0042,0,1,1.3,3.1
ENSMUSG00000075232,AMD1,S-adenosylmethionine decarboxylase 1,cytosol|,in utero embryonic development|polyamine biosynthetic process|spermine biosynthetic process|spermidine biosynthetic process|,adenosylmethionine decarboxylase activity|adenosylmethionine decarboxylase activity|protein binding|lyase activity|carboxy-lyase activity|putrescine binding|,6,0.9,22.5,6,1.3,18.4,1.2,39.9,39.9,0.0042,0,1,0.7,1.8
ENSMUSG00000038346,ZFP384,zinc finger protein 384,nucleus|focal adhesion|,nucleocytoplasmic transport|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein secretion|,SH3 domain binding|sequence-specific DNA binding|,10,0.7,10.1,10,1.1,31.4,0.8,39.5,39.5,0.00436,0,1,0.6,1.4
ENSMUSG00000034342,CBL,Casitas B-lineage lymphoma,nucleus|cytoplasm|plasma membrane|membrane|flotillin complex|,cell surface receptor signaling pathway|positive regulation of phosphatidylinositol 3-kinase signaling|regulation of signaling|negative regulation of apoptotic process|,"phosphotyrosine binding|ubiquitin-protein transferase activity|signal transducer activity|calcium ion binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|SH3 domain binding|SH3 domain binding|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|ephrin receptor binding|ephrin receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1.2,20,10,1.4,19.5,1.3,39,39,0.00452,0,1,0.8,2.1
ENSMUSG00000002257,DEF6,differentially expressed in FDCP 6,nucleus|cytoplasm|plasma membrane|cell-cell junction|membrane|membrane|,None,protein binding|,10,0.5,15.1,10,0.7,24.7,0.6,38.8,38.8,0.00458,0,1,0.5,1
ENSMUSG00000030061,UBA3,ubiquitin-like modifier activating enzyme 3,nucleus|nucleus|cytosol|,"mitotic cell cycle|cellular protein modification process|cell cycle|endomitotic cell cycle|protein neddylation|negative regulation of transcription, DNA-templated|regulation of cell cycle|","nucleotide binding|catalytic activity|protein binding|ATP binding|small protein activating enzyme activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ligand-dependent nuclear receptor binding|ribosomal S6-glutamic acid ligase activity|NEDD8 activating enzyme activity|NEDD8 activating enzyme activity|NEDD8 activating enzyme activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein heterodimerization activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1.4,16.1,10,1.5,23.1,1.5,38.7,38.7,0.00461,0,1,1.1,2.6
ENSMUSG00000029250,POLR2B,polymerase (RNA) II (DNA directed) polypeptide B,"nucleus|nucleus|DNA-directed RNA polymerase II, core complex|membrane|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|chromatin binding|DNA-directed RNA polymerase activity|transferase activity|nucleotidyltransferase activity|ribonucleoside binding|poly(A) RNA binding|metal ion binding|,7,0.5,5.25,7,1.7,37,0.8,38.5,38.5,0.00471,0,1,0.6,2.3
ENSMUSG00000066979,BUB3,budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae),"chromosome, centromeric region|kinetochore|nucleus|chromosome|",mitotic sister chromatid segregation|cell cycle|chromosome segregation|mitotic nuclear division|meiotic nuclear division|attachment of spindle microtubules to kinetochore|cell division|regulation of chromosome segregation|spindle assembly checkpoint|spindle assembly checkpoint|,None,8,1.1,20,7,1,19,1,38.4,38.4,0.00478,0,1,0.7,1.6
ENSMUSG00000021039,SNW1,SNW domain containing 1,chromatin|nucleus|spliceosomal complex|positive transcription elongation factor complex b|nuclear matrix|catalytic step 2 spliceosome|SMAD3-SMAD4 protein complex|,"negative regulation of transcription from RNA polymerase II promoter|mRNA splicing, via spliceosome|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|positive regulation of transforming growth factor beta receptor signaling pathway|skeletal muscle cell differentiation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation by host of viral transcription|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of mRNA splicing, via spliceosome|retinoic acid receptor signaling pathway|regulation of retinoic acid receptor signaling pathway|positive regulation of neurogenesis|positive regulation of histone H3-K4 methylation|regulation of vitamin D receptor signaling pathway|positive regulation of vitamin D receptor signaling pathway|cellular response to retinoic acid|cellular response to retinoic acid|",transcription coactivator activity|transcription corepressor activity|Notch binding|protein binding|nuclear hormone receptor binding|vitamin D receptor binding|retinoic acid receptor binding|poly(A) RNA binding|SMAD binding|,10,1.3,27.1,10,1,13.1,1.2,38.2,38.2,0.0049,0,1,0.8,1.7
ENSMUSG00000002748,BAZ1B,"bromodomain adjacent to zinc finger domain, 1B",condensed chromosome|nucleus|centromeric heterochromatin|nuclear replication fork|,"heart morphogenesis|double-strand break repair|chromatin assembly or disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|phosphorylation|histone phosphorylation|peptidyl-tyrosine phosphorylation|chromatin-mediated maintenance of transcription|positive regulation of receptor activity|",nucleotide binding|chromatin binding|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|zinc ion binding|kinase activity|transferase activity|histone kinase activity|histone binding|metal ion binding|lysine-acetylated histone binding|vitamin D receptor activator activity|,9,1,14.4,9,1.9,26.5,1.8,37.7,37.7,0.00515,0,1,0.8,2.5
ENSMUSG00000078789,DPH1,DPH1 homolog (S. cerevisiae),nucleus|cytoplasm|,cell proliferation|peptidyl-diphthamide biosynthetic process from peptidyl-histidine|,protein binding|,10,0.3,2.17,10,1,37.4,0.9,36.8,36.8,0.00563,0,1,0.5,1.7
ENSMUSG00000039244,E130309D02RIK,RIKEN cDNA E130309D02 gene,cellular_component|,biological_process|,molecular_function|,10,0.8,12.5,10,2,29.1,1.1,36,36,0.00611,0,0,0.9,2.7
ENSMUSG00000062867,IMPDH2,inosine 5'-phosphate dehydrogenase 2,nucleus|cytoplasm|peroxisomal membrane|membrane|extracellular vesicular exosome|,purine nucleotide biosynthetic process|purine nucleotide biosynthetic process|GMP biosynthetic process|lymphocyte proliferation|protein homotetramerization|oxidation-reduction process|cellular response to interleukin-4|,nucleotide binding|DNA binding|RNA binding|catalytic activity|IMP dehydrogenase activity|IMP dehydrogenase activity|oxidoreductase activity|adenyl nucleotide binding|metal ion binding|,8,1.6,1.77,9,1.6,34.3,1.6,35.7,35.7,0.00635,0,0,1.1,2.8
ENSMUSG00000038685,RTEL1,regulator of telomere elongation helicase 1,nucleus|,telomere maintenance|telomere maintenance|nucleobase-containing compound metabolic process|ATP catabolic process|DNA repair|cellular response to DNA damage stimulus|regulation of double-strand break repair via homologous recombination|DNA duplex unwinding|,"nucleotide binding|nucleic acid binding|DNA binding|ATP-dependent DNA helicase activity|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,1.6,27.7,10,0.9,12.1,1.1,35.2,35.2,0.00665,0,0,0.9,2.1
ENSMUSG00000030603,PSMC4,"proteasome (prosome, macropain) 26S subunit, ATPase, 4",proteasome complex|nucleus|cytoplasm|membrane|inclusion body|proteasome accessory complex|cytosolic proteasome complex|,blastocyst development|protein catabolic process|,nucleotide binding|ATP binding|hydrolase activity|,9,1.9,17.6,9,0.9,21.5,1.1,34.9,34.9,0.00678,0,0,0.6,2.2
ENSMUSG00000031787,KATNB1,katanin p80 (WD40-containing) subunit B 1,spindle pole|nucleus|cytoplasm|centrosome|cytoskeleton|microtubule|katanin complex|membrane|axon|axon|growth cone|midbody|neuronal cell body|,ATP catabolic process|negative regulation of microtubule depolymerization|cell cycle|mitotic nuclear division|positive regulation of cell death|positive regulation of neuron projection development|positive regulation of microtubule depolymerization|microtubule severing|cell division|,protein binding|microtubule binding|microtubule-severing ATPase activity|dynein binding|protein heterodimerization activity|,10,0.6,2.79,10,1.1,33,1,34.3,34.3,0.00729,0,0,0.7,1.5
ENSMUSG00000031530,DUSP4,dual specificity phosphatase 4,nucleus|,inactivation of MAPK activity|endoderm formation|protein dephosphorylation|protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,10,0.7,21.6,10,0.7,13.1,0.7,34.3,34.3,0.00729,0,0,0.5,1
ENSMUSG00000005625,PSMD4,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 4","proteasome complex|nucleus|cytoplasm|proteasome regulatory particle, base subcomplex|proteasome accessory complex|",ubiquitin-dependent protein catabolic process|,identical protein binding|poly(A) RNA binding|,10,1.1,30.2,10,-1.7,16.8,1,34.1,34.1,0.00742,0,0,0.7,1.6
ENSMUSG00000032555,TOPBP1,topoisomerase (DNA) II binding protein 1,condensed nuclear chromosome|male germ cell nucleus|nucleus|chromosome|chromosome|cytoplasm|cytoskeleton|plasma membrane|PML body|,DNA repair|cellular response to DNA damage stimulus|reciprocal meiotic recombination|response to ionizing radiation|,DNA binding|identical protein binding|,9,0.9,12.7,10,1,21.8,0.9,34,34,0.00747,0,0,0.7,1.6
ENSMUSG00000024824,RAD9A,RAD9 homolog A,nucleus|nucleus|cytoplasm|checkpoint clamp complex|,cell cycle checkpoint|DNA damage checkpoint|DNA damage checkpoint|DNA repair|cellular response to DNA damage stimulus|response to radiation|intra-S DNA damage checkpoint|cellular response to ionizing radiation|nucleic acid phosphodiester bond hydrolysis|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage|,nuclease activity|exonuclease activity|protein binding|3'-5' exonuclease activity|exodeoxyribonuclease III activity|hydrolase activity|SH3 domain binding|enzyme binding|protein kinase binding|histone deacetylase binding|,5,1.1,23.9,5,1.1,10.3,1.1,33.8,33.8,0.00762,0,0,0.8,1.8
ENSMUSG00000021244,YLPM1,YLP motif containing 1,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|regulation of telomere maintenance|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|poly(A) RNA binding|,10,-0.4,8.99,10,-0.8,27.9,-0.6,33.4,-33.4,0.00795,0,0,-1.1,-0.4
ENSMUSG00000005103,WDR1,WD repeat domain 1,cytoplasm|cytoskeleton|actin filament|actin cytoskeleton|cell junction|cell projection|extracellular vesicular exosome|,sensory perception of sound|regulation of oligodendrocyte differentiation|,actin binding|,10,1,11.7,10,0.8,22,1,33,33,0.00825,0,0,0.6,1.4
ENSMUSG00000032171,PIN1,protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1,nucleus|cytoplasm|midbody|,protein peptidyl-prolyl isomerization|positive regulation of protein phosphorylation|protein folding|cell cycle|negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of Rho GTPase activity|regulation of cytokinesis|regulation of cytokinesis|regulation of cell proliferation|positive regulation of ubiquitin-protein transferase activity|regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of ERK1 and ERK2 cascade|negative regulation of cell motility|,peptidyl-prolyl cis-trans isomerase activity|protein binding|isomerase activity|mitogen-activated protein kinase kinase binding|GTPase activating protein binding|phosphoserine binding|phosphothreonine binding|,10,0.6,15.6,10,0.6,17.9,0.6,33,33,0.00825,0,0,0.4,0.9
ENSMUSG00000008958,VPS72,vacuolar protein sorting 72 (yeast),nucleus|protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|somatic stem cell maintenance|",DNA binding|,10,0.5,5.02,10,1.6,31.9,1.2,32.4,32.4,0.00874,0,0,0.6,2.5
ENSMUSG00000024140,EPAS1,endothelial PAS domain protein 1,nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|cytoplasm|,"angiogenesis|response to hypoxia|response to hypoxia|embryonic placenta development|blood vessel remodeling|regulation of heart rate|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to oxidative stress|response to oxidative stress|mitochondrion organization|signal transduction|multicellular organismal development|visual perception|hemopoiesis|cell differentiation|erythrocyte differentiation|lung development|norepinephrine metabolic process|surfactant homeostasis|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|myoblast fate commitment|cellular response to hypoxia|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|signal transducer activity|transcription factor binding|transcription factor binding|histone acetyltransferase binding|sequence-specific DNA binding|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|,10,0.6,14.6,10,1.1,20.4,0.8,32.3,32.3,0.00884,0,0,0.5,1.3
ENSMUSG00000005378,WBSCR22,Williams Beuren syndrome chromosome region 22,cellular_component|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|biological_process|metabolic process|chromatin modification|ribosome biogenesis|",methyltransferase activity|poly(A) RNA binding|,9,0.9,21.5,9,0.6,13.2,0.8,32,32,0.00916,0,0,0.5,1.3
ENSMUSG00000070844,VMN2R42,"vomeronasal 2, receptor 42",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,6,1,11.3,6,1.3,21.2,1.2,31.3,31.3,0.01,0,0,0.8,1.9
ENSMUSG00000026914,PSMD14,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 14","proteasome complex|proteasome complex|nucleus|proteasome regulatory particle, lid subcomplex|proteasome accessory complex|extracellular vesicular exosome|",double-strand break repair via homologous recombination|DNA repair|double-strand break repair via nonhomologous end joining|proteolysis|cellular response to DNA damage stimulus|positive regulation of endopeptidase activity|regulation of proteasomal protein catabolic process|protein K63-linked deubiquitination|,endopeptidase activity|ubiquitin thiolesterase activity|protein binding|peptidase activity|metallopeptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|metal ion binding|endopeptidase activator activity|proteasome binding|,10,0.8,7.12,10,2.2,29,2.1,31,31,0.0104,0,0,1.1,3.4
ENSMUSG00000030846,TIAL1,Tia1 cytotoxic granule-associated RNA binding protein-like 1,nucleus|cytoplasm|cytoplasmic stress granule|extracellular vesicular exosome|,apoptotic process|germ cell development|positive regulation of cell proliferation|stem cell division|,nucleotide binding|nucleic acid binding|RNA binding|protein binding|AU-rich element binding|poly(A) RNA binding|,9,-0.7,17,9,-0.6,13.1,-0.7,29.7,-29.7,0.0126,0,0,-1.1,-0.5
ENSMUSG00000063694,CYCS,"cytochrome c, somatic",nucleus|mitochondrion|mitochondrion|cytosol|cytosol|,apoptotic DNA fragmentation|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|hydrogen peroxide metabolic process|,"electron carrier activity|heme binding|electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity|",9,0.9,16.3,9,1.1,13.7,0.9,29.5,29.5,0.0129,0,0,0.7,1.6
ENSMUSG00000002728,NAA20,"N(alpha)-acetyltransferase 20, NatB catalytic subunit",intracellular|nucleus|cytoplasm|,None,"peptide alpha-N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",9,1.3,5.19,9,1.9,25.5,1.9,29.2,29.2,0.0135,0,0,1.3,3
ENSMUSG00000021018,POLR2H,polymerase (RNA) II (DNA directed) polypeptide H,"nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase I complex|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase I activity|RNA polymerase II activity|RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|,8,1.9,4.08,8,1.9,25.2,1.9,28.9,28.9,0.0142,0,0,1.5,2.9
ENSMUSG00000028702,RAD54L,RAD54 like (S. cerevisiae),nucleus|,double-strand break repair via homologous recombination|DNA strand renaturation|DNA repair|double-strand break repair|cellular response to DNA damage stimulus|response to ionizing radiation|response to drug|chromosome organization|,"nucleotide binding|DNA binding|helicase activity|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|annealing helicase activity|",10,1,19.2,10,0.6,12.2,0.8,28.7,28.7,0.0147,0,0,0.5,1.3
ENSMUSG00000035674,NDUFA3,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,0.6,4.96,10,2.3,28.4,2.3,28.3,28.3,0.0155,0,0,1.2,3.5
ENSMUSG00000048755,MCAT,malonyl CoA:ACP acyltransferase (mitochondrial),mitochondrion|mitochondrion|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|metabolic process|,catalytic activity|[acyl-carrier-protein] S-malonyltransferase activity|transferase activity|poly(A) RNA binding|,10,0.8,15.2,10,0.6,14.2,0.7,28.3,28.3,0.0155,0,0,0.5,1.2
ENSMUSG00000057506,BLOC1S2,"biogenesis of lysosomal organelles complex-1, subunit 2",gamma-tubulin complex|intracellular|cell|nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|centrosome|centrosome|cytosol|cytoskeleton|BLOC-1 complex|BLOC-1 complex|BLOC-1 complex|recycling endosome|,"anterograde axon cargo transport|positive regulation of cell proliferation|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|neuron projection development|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|anterograde synaptic vesicle transport|mitochondrial outer membrane permeabilization|mitochondrial outer membrane permeabilization|",protein binding|protein C-terminus binding|gamma-tubulin binding|,10,0.8,14.4,10,1,14.9,0.9,28.3,28.3,0.0155,0,0,0.6,1.3
ENSMUSG00000020755,SAP30BP,SAP30 binding protein,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|positive regulation of cell death|",None,10,0.3,1.13,10,2.6,31.3,2.6,28.3,28.3,0.0155,0,0,1.6,4.5
ENSMUSG00000021548,CCNH,cyclin H,"nucleus|nucleus|holo TFIIH complex|DNA-directed RNA polymerase II, holoenzyme|cyclin-dependent protein kinase activating kinase holoenzyme complex|TFIIK complex|","regulation of cyclin-dependent protein serine/threonine kinase activity|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|protein phosphorylation|cell cycle|phosphorylation|positive regulation of transcription from RNA polymerase II promoter|regulation of cell cycle|",cyclin-dependent protein serine/threonine kinase activity|DNA-dependent ATPase activity|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|protein kinase binding|,10,1.2,11,10,1.1,17.5,1.1,28.1,28.1,0.0159,0,0,0.8,1.7
ENSMUSG00000009863,SDHB,"succinate dehydrogenase complex, subunit B, iron sulfur (Ip)",mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial respiratory chain complex II|membrane|respiratory chain complex II|extracellular vesicular exosome|,tricarboxylic acid cycle|succinate metabolic process|transport|respiratory electron transport chain|oxidation-reduction process|,"succinate dehydrogenase (ubiquinone) activity|electron carrier activity|oxidoreductase activity|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|3 iron, 4 sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,1.2,15.8,10,0.9,14.2,1.1,28,28,0.0162,0,0,0.7,1.7
ENSMUSG00000028560,USP1,ubiquitin specific peptidase 1,nucleus|,skeletal system development|DNA repair|regulation of DNA repair|proteolysis|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|response to UV|protein deubiquitination|monoubiquitinated protein deubiquitination|,ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0.6,3.17,10,1,25.7,0.9,27.9,27.9,0.0165,0,0,0.5,1.7
ENSMUSG00000008690,NCAPH2,"non-SMC condensin II complex, subunit H2",nucleus|membrane|,chromosome condensation|T cell differentiation in thymus|,None,10,0,0,10,1.7,31.2,1.7,27.8,27.8,0.0168,0,0,0.6,2.6
ENSMUSG00000090137,UBA52,ubiquitin A-52 residue ribosomal protein fusion product 1,intracellular|,None,None,1,0,0,1,2.2,28.7,2.1,27.7,27.7,0.0171,0,0,1.8,4
ENSMUSG00000001767,CRNKL1,"Crn, crooked neck-like 1 (Drosophila)",intracellular|nucleus|spliceosomal complex|catalytic step 2 spliceosome|,"spliceosomal complex assembly|mRNA splicing, via spliceosome|RNA processing|mRNA processing|RNA splicing|",RNA binding|poly(A) RNA binding|,10,0.4,1.74,10,1.5,28.3,0.7,26.8,26.8,0.0197,0,0,0.4,2.5
ENSMUSG00000032116,STT3A,"STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,protein glycosylation|protein N-linked glycosylation via asparagine|co-translational protein modification|,"oligosaccharyl transferase activity|dolichyl-diphosphooligosaccharide-protein glycotransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,1.2,10.7,10,0.9,17.3,1.1,26.4,26.4,0.0209,0,0,0.7,1.7
ENSMUSG00000030611,MRPS11,mitochondrial ribosomal protein S11,mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,10,0.8,14,10,0.9,13,0.8,26.3,26.3,0.0212,0,0,0.6,1.3
ENSMUSG00000024393,PRRC2A,proline-rich coiled-coil 2A,nucleus|cytoplasm|membrane|extracellular vesicular exosome|,biological_process|,poly(A) RNA binding|,10,-0.6,12.4,10,-0.6,13.4,-0.6,25.3,-25.3,0.0251,0,0,-1,-0.4
ENSMUSG00000057322,RPL38,ribosomal protein L38,intracellular|ribosome|cytosolic large ribosomal subunit|ribonucleoprotein complex|eukaryotic 80S initiation complex|,skeletal system development|skeletal system development|ossification|translation|regulation of translation|sensory perception of sound|90S preribosome assembly|middle ear morphogenesis|axial mesoderm development|,molecular_function|structural constituent of ribosome|,9,1.5,19.4,8,0.9,7.69,1.3,24.9,24.9,0.0267,0,0,0.8,2.3
ENSMUSG00000027835,PDCD10,programmed cell death 10,cytoplasm|Golgi apparatus|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,angiogenesis|apoptotic process|positive regulation of cell proliferation|negative regulation of apoptotic process|positive regulation of MAP kinase activity|,protein binding|protein homodimerization activity|protein N-terminus binding|,10,1,23.8,10,0.4,2.76,0.8,24.9,24.9,0.0267,0,0,0.6,1.5
ENSMUSG00000019738,POLR2I,polymerase (RNA) II (DNA directed) polypeptide I,"nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|","maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter|transcription-coupled nucleotide-excision repair|transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|",nucleic acid binding|DNA binding|DNA-directed RNA polymerase activity|zinc ion binding|metal ion binding|,10,0.5,8.95,10,0.9,17.4,0.8,24.9,24.9,0.0267,0,0,0.5,1.2
ENSMUSG00000006215,ZBTB17,zinc finger and BTB domain containing 17,nucleus|,"gastrulation with mouth forming second|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|ectoderm development|positive regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,0.6,4.92,10,0.8,20.2,0.7,24.6,24.6,0.0281,0,0,0.4,1.4
ENSMUSG00000031928,MRE11A,meiotic recombination 11 homolog A (S. cerevisiae),"chromosome, telomeric region|chromatin|nuclear chromatin|condensed nuclear chromosome|nucleus|nucleus|nucleoplasm|Mre11 complex|Mre11 complex|site of double-strand break|site of double-strand break|perinuclear region of cytoplasm|",telomere maintenance|DNA metabolic process|DNA repair|base-excision repair|nucleotide-excision repair|double-strand break repair|cellular response to DNA damage stimulus|sister chromatid cohesion|mitotic G2 DNA damage checkpoint|meiotic nuclear division|synapsis|cell proliferation|intra-S DNA damage checkpoint|positive regulation of protein autophosphorylation|DNA duplex unwinding|negative regulation of DNA endoreduplication|positive regulation of kinase activity|chromosome organization|nucleic acid phosphodiester bond hydrolysis|,DNA binding|ATP-dependent DNA helicase activity|nuclease activity|endonuclease activity|exonuclease activity|protein C-terminus binding|3'-5' exonuclease activity|hydrolase activity|manganese ion binding|,10,0.9,17.9,10,0.8,6.9,0.8,24.3,24.3,0.0294,0,0,0.4,1.3
ENSMUSG00000027641,RBL1,retinoblastoma-like 1 (p107),nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|cell cycle|chromatin modification|regulation of lipid kinase activity|regulation of cell cycle|",protein binding|transcription factor binding|,10,1.2,8.28,10,0.8,16.6,1.1,24.2,24.2,0.03,0,0,0.7,1.8
ENSMUSG00000019773,FBXO5,F-box protein 5,nucleus|cytoplasm|cytoplasm|spindle|cytoskeleton|,oocyte maturation|oocyte maturation|cell cycle|spindle assembly involved in female meiosis I|mitotic nuclear division|regulation of mitotic cell cycle|vesicle organization|regulation of meiosis|negative regulation of meiosis|microtubule polymerization|spindle assembly|cell division|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle|inhibition of mitotic anaphase-promoting complex activity|positive regulation of meiosis I|,protein binding|protein kinase binding|metal ion binding|,10,0.8,12.4,10,1.2,12.5,0.9,24.1,24.1,0.0304,0,0,0.6,1.7
ENSMUSG00000021377,DEK,DEK oncogene (DNA binding),nucleus|,chromatin modification|regulation of double-strand break repair|regulation of double-strand break repair via nonhomologous end joining|,nucleic acid binding|DNA binding|histone binding|poly(A) RNA binding|,10,0.9,14.1,10,0.7,10.6,0.8,24,24,0.0308,0,0,0.6,1.4
ENSMUSG00000028032,PAPSS1,3'-phosphoadenosine 5'-phosphosulfate synthase 1,sulfate adenylyltransferase complex (ATP)|,sulfate assimilation|metabolic process|phosphorylation|3'-phosphoadenosine 5'-phosphosulfate biosynthetic process|,nucleotide binding|catalytic activity|adenylylsulfate kinase activity|sulfate adenylyltransferase (ATP) activity|ATP binding|kinase activity|transferase activity|nucleotidyltransferase activity|,10,0.6,9.49,10,0.7,14.8,0.6,23.8,23.8,0.0318,0,0,0.4,1
ENSMUSG00000005610,EIF4G2,"eukaryotic translation initiation factor 4, gamma 2",cytoplasm|membrane|eukaryotic translation initiation factor 4F complex|,translation|translational initiation|regulation of translation|regulation of translational initiation|regulation of translational initiation|,"RNA binding|translation initiation factor activity|translation initiation factor activity|protein binding|translation factor activity, nucleic acid binding|poly(A) RNA binding|",10,1.1,20.5,10,0.8,4.03,1,23.6,23.6,0.0328,0,0,0.7,1.7
ENSMUSG00000022477,ACO2,"aconitase 2, mitochondrial",nucleus|mitochondrion|mitochondrion|,tricarboxylic acid cycle|citrate metabolic process|isocitrate metabolic process|metabolic process|,"aconitate hydratase activity|aconitate hydratase activity|iron ion binding|lyase activity|metal ion binding|iron-sulfur cluster binding|3 iron, 4 sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.5,10.5,10,0.7,13.7,0.6,23.6,23.6,0.0328,0,0,0.4,1.1
ENSMUSG00000027331,KNSTRN,kinetochore-localized astrin/SPAG5 binding,"chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|microtubule plus-end|mitotic spindle|",mitotic sister chromatid segregation|cell cycle|spindle organization|chromosome segregation|mitotic nuclear division|cell division|regulation of attachment of spindle microtubules to kinetochore|,protein binding|,10,0.9,1.85,10,2.4,24.3,2.4,23.5,23.5,0.0334,0,0,1.8,4
ENSMUSG00000025474,TUBGCP2,"tubulin, gamma complex associated protein 2",spindle pole|cytoplasm|centrosome|microtubule organizing center|cytoskeleton|microtubule|membrane|,microtubule cytoskeleton organization|biological_process|,molecular_function|,10,0.3,2.9,10,2.1,26.1,2.1,23.5,23.5,0.0334,0,0,1.4,4
ENSMUSG00000071573,RNLS,"renalase, FAD-dependent amine oxidase",cellular_component|extracellular region|extracellular space|,regulation of systemic arterial blood pressure|cardiac left ventricle morphogenesis|epinephrine metabolic process|norepinephrine metabolic process|dopamine metabolic process|phosphate ion homeostasis|oxidation-reduction process|heart contraction|response to norepinephrine|response to salt|,oxidoreductase activity|,9,0,0,10,1.5,26.3,1.5,23,23,0.0363,0,0,0.8,3
ENSMUSG00000041431,CCNB1,cyclin B1,spindle pole|condensed nuclear chromosome outer kinetochore|nucleus|nucleus|cytoplasm|centrosome|cytoskeleton|membrane|,regulation of cyclin-dependent protein serine/threonine kinase activity|oocyte maturation|in utero embryonic development|negative regulation of protein phosphorylation|protein complex assembly|protein phosphorylation|cell cycle|mitotic nuclear division|mitotic metaphase plate congression|negative regulation of gene expression|histone phosphorylation|positive regulation of mRNA 3'-end processing|positive regulation of histone phosphorylation|mitotic spindle stabilization|positive regulation of mitotic cell cycle|cell division|regulation of cell cycle|positive regulation of attachment of spindle microtubules to kinetochore|positive regulation of cardiac muscle cell proliferation|regulation of chromosome condensation|mitotic spindle checkpoint|,patched binding|protein binding|kinase activity|protein kinase binding|protein complex binding|histone kinase activity|,10,1.6,1.55,10,1.2,22.3,1.3,22.9,22.9,0.037,0,0,0.8,2.6
ENSMUSG00000035262,AMH,anti-Mullerian hormone,extracellular region|extracellular space|cytoplasm|,ovarian follicle development|preantral ovarian follicle growth|urogenital system development|Mullerian duct regression|positive regulation of gene expression|positive regulation of NF-kappaB transcription factor activity|,receptor binding|transforming growth factor beta receptor binding|growth factor activity|,10,0,0,10,1.5,25.7,1.5,22.4,22.4,0.0402,0,0,0.6,2.9
ENSMUSG00000049717,LIG4,"ligase IV, DNA, ATP-dependent",condensed chromosome|nucleus|chromosome|cytoplasm|plasma membrane|focal adhesion|DNA-dependent protein kinase-DNA ligase 4 complex|DNA-dependent protein kinase-DNA ligase 4 complex|DNA ligase IV complex|DNA ligase IV complex|nonhomologous end joining complex|,"single strand break repair|in utero embryonic development|pro-B cell differentiation|DNA replication|DNA ligation|DNA ligation|DNA ligation|lagging strand elongation|DNA repair|nucleotide-excision repair|nucleotide-excision repair, DNA gap filling|double-strand break repair|double-strand break repair|double-strand break repair|double-strand break repair via nonhomologous end joining|double-strand break repair via nonhomologous end joining|DNA recombination|cellular response to DNA damage stimulus|cell cycle|central nervous system development|central nervous system development|cell proliferation|response to X-ray|response to ionizing radiation|response to gamma radiation|T cell differentiation in thymus|V(D)J recombination|V(D)J recombination|V(D)J recombination|immunoglobulin V(D)J recombination|T cell receptor V(D)J recombination|somatic stem cell maintenance|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|isotype switching|positive regulation of fibroblast proliferation|positive regulation of neurogenesis|DNA ligation involved in DNA recombination|DNA ligation involved in DNA repair|DNA ligation involved in DNA repair|chromosome organization|cell division|neuron apoptotic process|DNA biosynthetic process|",nucleotide binding|DNA binding|DNA ligase activity|DNA ligase (ATP) activity|DNA ligase (ATP) activity|protein binding|ATP binding|ATP binding|protein C-terminus binding|ligase activity|metal ion binding|,10,0.3,4.21,10,1.7,24.1,1.7,22.3,22.3,0.0409,0,0,0.6,2.8
ENSMUSG00000030435,U2AF2,U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2,nucleus|spliceosomal complex|nuclear speck|nuclear speck|virion|viral nucleocapsid|ribonucleoprotein complex|,"mRNA processing|RNA splicing|negative regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|enzyme binding|poly(A) RNA binding|C2H2 zinc finger domain binding|,10,1.5,13.3,8,0.9,11.5,1.4,22.2,22.2,0.0416,0,0,0.9,2.2
ENSMUSG00000003037,RAB8A,"RAB8A, member RAS oncogene family",endosome|Golgi apparatus|centrosome|plasma membrane|plasma membrane|cilium|cilium|cilium|postsynaptic density|membrane|cytoplasmic membrane-bounded vesicle|trans-Golgi network transport vesicle|dendrite|cytoplasmic vesicle|nonmotile primary cilium|nonmotile primary cilium|ciliary basal body|cell projection|neuronal cell body|phagocytic vesicle|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|,GTP catabolic process|transport|vesicle docking involved in exocytosis|small GTPase mediated signal transduction|axonogenesis|protein transport|cell projection organization|cellular response to insulin stimulus|regulation of protein localization|cilium assembly|regulation of long-term neuronal synaptic plasticity|Golgi vesicle fusion to target membrane|regulation of protein transport|protein localization to plasma membrane|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|protein kinase binding|,10,0.9,21,10,0.5,4.03,0.8,22.1,22.1,0.0423,0,0,0.4,1.4
ENSMUSG00000021149,GTPBP4,GTP binding protein 4,nucleus|nucleolus|cytoplasm|Golgi apparatus|membrane|nuclear membrane|perinuclear region of cytoplasm|,regulation of cyclin-dependent protein serine/threonine kinase activity|osteoblast differentiation|GTP catabolic process|negative regulation of DNA replication|negative regulation of cell proliferation|negative regulation of cell-cell adhesion|negative regulation of cell migration|negative regulation of protein ubiquitination|negative regulation of collagen binding|ribosome biogenesis|protein stabilization|,nucleotide binding|GTPase activity|GTP binding|poly(A) RNA binding|,10,0.8,15.5,10,0.4,8.38,0.6,22.1,22.1,0.0423,0,0,0.4,1
ENSMUSG00000025860,XIAP,X-linked inhibitor of apoptosis,nucleus|cytoplasm|cytoplasm|cytosol|protein complex|perinuclear region of cytoplasm|,apoptotic process|Wnt signaling pathway|protein ubiquitination|positive regulation of protein ubiquitination|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of neuron apoptotic process|neuron apoptotic process|positive regulation of canonical Wnt signaling pathway|positive regulation of protein linear polyubiquitination|inhibition of cysteine-type endopeptidase activity involved in apoptotic process|,"protease binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|scaffold protein binding|",10,-0.7,15.6,10,-1,7.61,-0.8,22,-22,0.043,0,0,-1.4,-0.4
ENSMUSG00000005233,SPC25,"SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)","chromosome, centromeric region|kinetochore|condensed chromosome kinetochore|nucleus|chromosome|Ndc80 complex|",cell cycle|mitotic spindle organization|chromosome segregation|mitotic nuclear division|cell division|,molecular_function|,9,0.9,18,10,1,4.2,0.9,21.8,21.8,0.0446,0,0,0.5,1.6
ENSMUSG00000022193,PSMB5,"proteasome (prosome, macropain) subunit, beta type 5",proteasome complex|nucleus|cytoplasm|proteasome core complex|extracellular vesicular exosome|,proteolysis|response to oxidative stress|proteasome-mediated ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,0.6,14.7,10,0.5,7.82,0.5,21.8,21.8,0.0446,0,0,0.4,0.9
ENSMUSG00000028447,DCTN3,dynactin 3,"chromosome, centromeric region|kinetochore|chromosome|cytoplasm|centrosome|cytoskeleton|dynactin complex|dynactin complex|microtubule associated complex|perinuclear region of cytoplasm|",cytokinesis|microtubule-based process|cell cycle|mitotic nuclear division|cell division|,molecular_function|,9,0.5,4.82,10,0.8,18.2,0.8,21.7,21.7,0.0453,0,0,0.4,1.4
ENSMUSG00000008855,HDAC5,histone deacetylase 5,histone deacetylase complex|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|Golgi apparatus|cytosol|nuclear body|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|osteoblast development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|inflammatory response|nervous system development|heart development|regulation of myotube differentiation|negative regulation of myotube differentiation|chromatin modification|histone deacetylation|histone deacetylation|B cell differentiation|multicellular organismal response to stress|B cell activation|response to cocaine|response to cocaine|response to drug|regulation of protein binding|negative regulation of osteoblast differentiation|negative regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of skeletal muscle fiber development|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of striated muscle cell differentiation|renal tubule morphogenesis|cellular response to fluid shear stress|negative regulation of cell migration involved in sprouting angiogenesis|positive regulation of neural precursor cell proliferation|positive regulation of stem cell proliferation|",core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding|transcription corepressor activity|transcription corepressor activity|histone deacetylase activity|histone deacetylase activity|protein kinase C binding|protein binding|transcription factor binding|transcription factor binding|transcription factor binding|hydrolase activity|protein kinase binding|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|histone deacetylase activity (H4-K16 specific)|transcription regulatory region DNA binding|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|repressing transcription factor binding|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,-0.4,13,10,-0.6,9.68,-0.5,21.7,-21.7,0.0453,0,0,-0.9,-0.3
ENSMUSG00000027959,SASS6,spindle assembly 6 homolog (C. elegans),cytoplasm|centrosome|centriole|centriole|cytoskeleton|deuterosome|,cell cycle|centriole replication|centrosome duplication|,molecular_function|,10,-0.2,0.479,10,1.1,24.8,1,21.6,21.6,0.046,0,0,0.7,1.8
ENSMUSG00000025366,ESYT1,extended synaptotagmin-like protein 1,endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,transport|lipid transport|,lipid binding|metal ion binding|,10,0.3,5.59,10,0.6,17.3,0.5,21.6,21.6,0.046,0,0,0.4,1
ENSMUSG00000078941,TAF9,"TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor",PCAF complex|nucleus|transcription factor TFIID complex|STAGA complex|transcription factor TFTC complex|pre-snoRNP complex|MLL1 complex|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|positive regulation of cell growth|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|histone H3 acetylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein stabilization|positive regulation of response to cytokine stimulus|response to interleukin-1|",p53 binding|DNA binding|DNA binding|transcription coactivator activity|histone acetyltransferase activity|activating transcription factor binding|transcription regulatory region DNA binding|protein heterodimerization activity|C2H2 zinc finger domain binding|,9,0.8,15,9,1,7.18,0.8,21.6,21.6,0.046,0,0,0.5,1.5
ENSMUSG00000036850,MRPL41,mitochondrial ribosomal protein L41,mitochondrion|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|apoptotic process|cell cycle|,structural constituent of ribosome|poly(A) RNA binding|,10,0.7,0.617,10,0.9,20.8,0.9,21.1,21.1,0.0499,0,0,0.6,1.5
ENSMUSG00000041840,HAUS1,"HAUS augmin-like complex, subunit 1",cytoplasm|centrosome|cytoskeleton|microtubule|HAUS complex|,cell cycle|mitotic nuclear division|spindle assembly|centrosome organization|cell division|,molecular_function|,10,1.3,20.5,10,0.7,2.46,1.2,20.9,20.9,0.0517,0,0,0.9,1.9
ENSMUSG00000002416,NDUFB2,"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,0.6,13.8,10,0.5,7.36,0.6,20.6,20.6,0.0547,0,0,0.4,1
ENSMUSG00000002835,CHAF1A,"chromatin assembly factor 1, subunit A (p150)",nuclear chromatin|nucleus|CAF-1 complex|protein complex|,"DNA replication|DNA repair|DNA replication-dependent nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle|chromatin assembly|",protein binding|identical protein binding|chromo shadow domain binding|,10,1.5,12.4,10,-1.9,23.4,-1.9,20.4,-20.4,0.0567,0,0,-3,1.6
ENSMUSG00000040383,AQR,aquarius,nucleus|spliceosomal complex|membrane|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|mRNA processing|biological_process|RNA splicing|",RNA binding|poly(A) RNA binding|,9,0.7,13.9,8,0.5,7.21,0.6,20,20,0.0609,0,0,0.4,1.1
ENSMUSG00000072258,TAF1A,"TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A",RNA polymerase I transcription factor complex|nucleus|microtubule cytoskeleton|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase I promoter|",DNA binding|protein binding|,10,0.6,9.42,10,0.6,11,0.6,20,20,0.0609,0,0,0.4,1
ENSMUSG00000025487,PSMD13,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 13",proteasome complex|nucleus|proteasome regulatory particle|membrane|proteasome accessory complex|extracellular vesicular exosome|,proteolysis|meiosis I|,endopeptidase activity|,10,1.9,20.8,9,-1.4,7.54,1.8,19.8,19.8,0.0633,0,0,1,3.5
ENSMUSG00000037808,FAM76B,"family with sequence similarity 76, member B",nucleus|nuclear membrane|,biological_process|,molecular_function|,10,-0.7,2.34,10,1.6,22.9,1.6,19.8,19.8,0.0633,0,0,1,3
ENSMUSG00000024370,CDC23,CDC23 cell division cycle 23,intracellular|anaphase-promoting complex|,mitotic G1 phase|cell cycle|mitotic nuclear division|mitotic metaphase plate congression|regulation of mitotic metaphase/anaphase transition|cell division|protein K11-linked ubiquitination|,molecular_function|,9,0.8,15.1,10,0.5,6.32,0.7,19.8,19.8,0.0633,0,0,0.4,1.2
ENSMUSG00000032410,XRN1,5'-3' exoribonuclease 1,cytoplasmic mRNA processing body|cytoplasm|membrane|,"telomere maintenance|nuclear-transcribed mRNA catabolic process|RNA processing|meiotic nuclear division|cell aging|rRNA catabolic process|nuclear mRNA surveillance|histone mRNA catabolic process|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|nucleic acid binding|DNA binding|RNA binding|nuclease activity|exonuclease activity|5'-3' exoribonuclease activity|5'-3' exonuclease activity|hydrolase activity|poly(A) RNA binding|,10,0.6,5.64,10,0.8,14.5,0.7,19.7,19.7,0.0645,0,0,0.4,1.1
ENSMUSG00000024218,TAF11,"TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|Golgi apparatus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|positive regulation by host of viral transcription|",DNA binding|transcription coactivator activity|vitamin D receptor binding|thyroid hormone receptor binding|protein heterodimerization activity|protein N-terminus binding|,10,-0.9,5.27,10,1.3,20.8,0.5,19.6,19.6,0.0656,0,0,0.3,1.8
ENSMUSG00000027285,HAUS2,"HAUS augmin-like complex, subunit 2",nucleus|cytoplasm|Golgi apparatus|centrosome|cytoskeleton|microtubule|HAUS complex|,cell cycle|mitotic nuclear division|microtubule organizing center organization|spindle assembly|centrosome organization|cell division|,molecular_function|,10,0.1,0.154,10,2.1,22.9,2.1,19.5,19.5,0.0669,0,0,1.6,4
ENSMUSG00000045521,TSSK2,testis-specific serine kinase 2,acrosomal vesicle|nucleus|cytoplasm|centriole|cytoskeleton|cytoplasmic vesicle|,protein phosphorylation|multicellular organismal development|spermatogenesis|spermatid development|phosphorylation|cell differentiation|protein autophosphorylation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.5,2.33,10,1.8,22.7,1.8,19.3,19.3,0.0691,0,0,1.3,3
ENSMUSG00000020594,PUM2,pumilio RNA-binding family member 2,cytoplasm|cytoplasmic stress granule|dendrite|nuclear membrane|neuronal cell body|perinuclear region of cytoplasm|,regulation of translation|stress granule assembly|stress granule assembly|,RNA binding|protein binding|poly(A) RNA binding|,10,-0.7,14.2,10,-0.7,5.06,-0.7,18.9,-18.9,0.0739,0,0,-1.2,-0.4
ENSMUSG00000072845,TMPRSS11A,"transmembrane protease, serine 11a",cellular_component|extracellular region|integral component of plasma membrane|membrane|integral component of membrane|,proteolysis|cell cycle|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.554,10,-2,22.2,-2,18.8,-18.8,0.0749,0,0,-4,-1.5
ENSMUSG00000032185,CARM1,coactivator-associated arginine methyltransferase 1,nucleus|nucleus|cytoplasm|cytosol|,"regulation of growth plate cartilage chondrocyte proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein methylation|positive regulation of cell proliferation|positive regulation of cell proliferation|pathogenesis|chromatin modification|histone methylation|histone methylation|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|intracellular steroid hormone receptor signaling pathway|intracellular estrogen receptor signaling pathway|negative regulation of protein binding|methylation|regulation of intracellular estrogen receptor signaling pathway|histone arginine methylation|histone H3-R2 methylation|histone H3-R17 methylation|positive regulation of fat cell differentiation|response to cAMP|endochondral bone morphogenesis|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|transcription coactivator activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|ligand-dependent nuclear receptor transcription coactivator activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|histone methyltransferase activity (H3-R17 specific)|histone methyltransferase activity|histone methyltransferase activity|protein homodimerization activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|transcription regulatory region DNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|lysine-acetylated histone binding|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,0.6,9.22,8,0.6,9.9,0.6,18.7,18.7,0.076,0,0,0.4,1.1
ENSMUSG00000026496,PARP1,"poly (ADP-ribose) polymerase family, member 1",nucleus|nucleus|nucleus|nuclear envelope|nucleoplasm|transcription factor complex|nucleolus|nucleolus|cytoplasm|membrane|protein complex|,"telomere maintenance|DNA metabolic process|DNA repair|base-excision repair|double-strand break repair|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein ADP-ribosylation|cellular response to DNA damage stimulus|transforming growth factor beta receptor signaling pathway|protein autoprocessing|signal transduction involved in regulation of gene expression|cellular response to insulin stimulus|regulation of growth rate|DNA damage response, detection of DNA damage|positive regulation of transcription from RNA polymerase II promoter|positive regulation of SMAD protein import into nucleus|protein poly-ADP-ribosylation|cellular response to superoxide|positive regulation of transcription regulatory region DNA binding|","DNA binding|NAD+ ADP-ribosyltransferase activity|protein binding|transcription factor binding|zinc ion binding|transferase activity|transferase activity, transferring glycosyl groups|enzyme binding|identical protein binding|poly(A) RNA binding|metal ion binding|protein N-terminus binding|NAD binding|R-SMAD binding|",10,0.5,8.9,10,0.5,10.2,0.5,18.7,18.7,0.076,0,0,0.3,0.8
ENSMUSG00000046179,E2F8,E2F transcription factor 8,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|placenta development|sprouting angiogenesis|sprouting angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell cycle|cell proliferation|negative regulation of cytokinesis|positive regulation of DNA endoreduplication|cell cycle comprising mitosis without cytokinesis|positive regulation of transcription from RNA polymerase II promoter|trophoblast giant cell differentiation|chorionic trophoblast cell differentiation|hepatocyte differentiation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|core promoter binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|identical protein binding|protein homodimerization activity|,10,-0.4,3.45,10,-0.6,15.4,-0.5,18.3,-18.3,0.0795,0,0,-1.3,-0.3
ENSMUSG00000027427,POLR3F,polymerase (RNA) III (DNA directed) polypeptide F,nucleus|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|,"immune system process|transcription, DNA-templated|positive regulation of interferon-beta production|innate immune response|positive regulation of innate immune response|defense response to virus|",RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|,10,-1.3,2.88,10,1.2,18.6,1,18.3,18.3,0.0795,0,0,0.7,1.9
ENSMUSG00000026245,FARSB,"phenylalanyl-tRNA synthetase, beta subunit",cytoplasm|membrane|,translation|phenylalanyl-tRNA aminoacylation|,nucleotide binding|magnesium ion binding|RNA binding|aminoacyl-tRNA ligase activity|phenylalanine-tRNA ligase activity|ATP binding|ligase activity|,9,0.9,12.4,10,0.5,7.36,0.7,18.3,18.3,0.0795,0,0,0.4,1.3
ENSMUSG00000028599,TNFRSF1B,"tumor necrosis factor receptor superfamily, member 1b",intracellular|nucleus|membrane|membrane|integral component of membrane|axon|neuronal cell body|varicosity|membrane raft|membrane raft|perinuclear region of cytoplasm|,inflammatory response|immune response|cell surface receptor signaling pathway|cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage|programmed cell death|tumor necrosis factor-mediated signaling pathway|negative regulation of inflammatory response|RNA destabilization|positive regulation of membrane protein ectodomain proteolysis|cellular response to lipopolysaccharide|extrinsic apoptotic signaling pathway|,tumor necrosis factor-activated receptor activity|tumor necrosis factor-activated receptor activity|protein binding|ubiquitin protein ligase binding|,10,0.8,13.8,10,0.4,6.51,0.6,18.3,18.3,0.0795,0,0,0.4,1.1
ENSMUSG00000021952,XPO4,exportin 4,nucleus|cytoplasm|,transport|protein transport|positive regulation of protein export from nucleus|,None,10,0.5,7.7,10,1.2,12.9,0.8,18.1,18.1,0.081,0,0,0.3,1.5
ENSMUSG00000025204,NDUFB8,NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial respiratory chain complex I|endoplasmic reticulum|membrane|integral component of membrane|respiratory chain|,"mitochondrial electron transport, NADH to ubiquinone|transport|biological_process|oxidation-reduction process|",molecular_function|NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|,10,0.9,17.9,10,0.3,2.2,0.9,18.1,18.1,0.081,0,0,0.4,1.6
ENSMUSG00000027353,MCM8,minichromosome maintenance deficient 8 (S. cerevisiae),nucleus|MCM8-MCM9 complex|MCM8-MCM9 complex|,double-strand break repair via homologous recombination|DNA replication|DNA repair|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|cell cycle|female gamete generation|male gamete generation|,nucleotide binding|molecular_function|DNA binding|helicase activity|ATP binding|hydrolase activity|,10,0.6,6.48,10,1.2,13.4,0.8,17.8,17.8,0.0834,0,0,0.3,1.7
ENSMUSG00000029725,PPP1R35,"protein phosphatase 1, regulatory subunit 35",cellular_component|,negative regulation of phosphatase activity|,protein phosphatase inhibitor activity|phosphatase binding|,10,0.5,8.43,10,0.7,10,0.6,17.8,17.8,0.0834,0,0,0.3,1.2
ENSMUSG00000020409,SLU7,SLU7 splicing factor homolog (S. cerevisiae),nucleus|spliceosomal complex|cytoplasm|membrane|nuclear speck|small nuclear ribonucleoprotein complex|intracellular membrane-bounded organelle|catalytic step 2 spliceosome|,"RNA splicing, via transesterification reactions|alternative mRNA splicing, via spliceosome|mRNA 3'-splice site recognition|mRNA processing|intracellular protein transport|RNA splicing|cellular response to heat|",second spliceosomal transesterification activity|nucleic acid binding|zinc ion binding|pre-mRNA 3'-splice site binding|metal ion binding|,10,0.8,11.5,10,0.7,6.78,0.7,17.8,17.8,0.0834,0,0,0.4,1.3
ENSMUSG00000029726,MEPCE,methylphosphate capping enzyme,cellular_component|,negative regulation of transcription from RNA polymerase II promoter|RNA methylation|snRNA metabolic process|methylation|negative regulation of chromatin binding|snRNA modification|positive regulation of G1/S transition of mitotic cell cycle|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,1.2,17.7,10,0.4,1.55,1.1,17.7,17.7,0.0839,0,0,0.8,2
ENSMUSG00000029819,NPY,neuropeptide Y,extracellular region|extracellular space|,neuropeptide signaling pathway|regulation of blood pressure|,G-protein coupled receptor binding|G-protein coupled receptor binding|hormone activity|neuropeptide Y receptor binding|,10,-0.6,0.347,10,-1.8,19.6,-1.7,17.7,-17.7,0.0839,0,0,-3,-0.3
ENSMUSG00000033054,NPAT,nuclear protein in the AT region,nucleus|nucleoplasm|cytoplasm|Cajal body|Gemini of coiled bodies|,"regulation of transcription involved in G1/S transition of mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|regulation of gene expression|positive regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription corepressor activity|protein C-terminus binding|protein N-terminus binding|,9,0.5,3.16,9,1.4,17.3,1.3,17.5,17.5,0.0853,0,0,0.5,2
ENSMUSG00000024026,GLO1,glyoxalase 1,extracellular vesicular exosome|,carbohydrate metabolic process|regulation of transcription from RNA polymerase II promoter|glutathione metabolic process|methylglyoxal metabolic process|osteoclast differentiation|negative regulation of apoptotic process|,lactoylglutathione lyase activity|lactoylglutathione lyase activity|zinc ion binding|zinc ion binding|lyase activity|metal ion binding|,10,0.8,17.6,10,0.2,1.41,0.7,17.5,17.5,0.0853,0,0,0.4,1.3
ENSMUSG00000036093,ARL5A,ADP-ribosylation factor-like 5A,cellular_component|intracellular|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0.7,17.2,10,0.2,1.38,0.7,17.4,17.4,0.086,0,0,0.4,1.3
ENSMUSG00000025574,TK1,thymidine kinase 1,cytoplasm|,DNA replication|deoxyribonucleoside monophosphate biosynthetic process|nucleotide biosynthetic process|nucleotide biosynthetic process|phosphorylation|thymidine metabolic process|protein homotetramerization|,nucleotide binding|thymidine kinase activity|ATP binding|zinc ion binding|kinase activity|transferase activity|nucleoside kinase activity|identical protein binding|metal ion binding|,6,0.5,6.56,6,0.7,11.4,0.7,17.3,17.3,0.0867,0,0,0.4,1.4
ENSMUSG00000014769,PSMB1,"proteasome (prosome, macropain) subunit, beta type 1",proteasome complex|nucleus|cytoplasm|proteasome core complex|extracellular vesicular exosome|,proteolysis|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,9,0.9,13.1,9,0.5,5.03,0.8,17.2,17.2,0.0873,0,0,0.4,1.5
ENSMUSG00000029623,PDAP1,PDGFA associated protein 1,extracellular space|,platelet-derived growth factor receptor signaling pathway|,poly(A) RNA binding|platelet-derived growth factor binding|,10,0.5,11.1,10,0.4,6.33,0.5,17,17,0.0884,0,0,0.3,0.8
ENSMUSG00000055041,COMMD5,COMM domain containing 5,nucleus|,None,molecular_function|,10,0.8,13.8,10,-1.1,17,0.8,16.9,16.9,0.089,0,0,-1.4,2
ENSMUSG00000024515,SMAD4,SMAD family member 4,nuclear chromatin|intracellular|nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|cytoplasm|centrosome|activin responsive factor complex|protein complex|SMAD protein complex|,"branching involved in ureteric bud morphogenesis|response to hypoxia|in utero embryonic development|gastrulation with mouth forming second|kidney development|atrioventricular valve formation|epithelial to mesenchymal transition involved in endocardial cushion formation|positive regulation of cell proliferation involved in heart valve morphogenesis|cardiac septum development|brainstem development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|SMAD protein complex assembly|gastrulation|axon guidance|endoderm development|mesoderm development|cell proliferation|negative regulation of cell proliferation|anterior/posterior pattern specification|positive regulation of epithelial to mesenchymal transition|positive regulation of pathway-restricted SMAD protein phosphorylation|neural crest cell differentiation|regulation of transforming growth factor beta receptor signaling pathway|negative regulation of cell growth|BMP signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of BMP signaling pathway|somite rostral/caudal axis specification|regulation of transforming growth factor beta2 production|intracellular signal transduction|atrioventricular canal development|endothelial cell activation|regulation of cell proliferation|regulation of cell proliferation|negative regulation of protein catabolic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|developmental growth|neuron fate commitment|tissue morphogenesis|sebaceous gland development|formation of anatomical boundary|regulation of binding|regulation of hair follicle development|palate development|positive regulation of SMAD protein import into nucleus|SMAD protein signal transduction|negative regulation of cell death|endocardial cell differentiation|response to transforming growth factor beta|metanephric mesenchyme morphogenesis|nephrogenic mesenchyme morphogenesis|","core promoter proximal region sequence-specific DNA binding|protein binding transcription factor activity|RNA polymerase II transcription factor binding transcription factor activity|RNA polymerase II transcription factor binding|DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|collagen binding|transforming growth factor beta receptor, common-partner cytoplasmic mediator activity|filamin binding|identical protein binding|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|SMAD binding|metal ion binding|I-SMAD binding|R-SMAD binding|",10,0.4,4.34,10,0.5,13.1,0.5,16.6,16.6,0.0908,0,0,0.2,0.8
ENSMUSG00000021615,XRCC4,X-ray repair complementing defective repair in Chinese hamster cells 4,nucleus|centrosome|cytosol|DNA-dependent protein kinase-DNA ligase 4 complex|DNA-dependent protein kinase-DNA ligase 4 complex|cell junction|DNA ligase IV complex|nonhomologous end joining complex|,in utero embryonic development|pro-B cell differentiation|DNA ligation|DNA repair|double-strand break repair|double-strand break repair|double-strand break repair via nonhomologous end joining|double-strand break repair via nonhomologous end joining|DNA recombination|cellular response to DNA damage stimulus|central nervous system development|response to X-ray|response to X-ray|response to ionizing radiation|response to gamma radiation|T cell differentiation in thymus|V(D)J recombination|immunoglobulin V(D)J recombination|negative regulation of neuron apoptotic process|isotype switching|positive regulation of fibroblast proliferation|positive regulation of neurogenesis|DNA ligation involved in DNA repair|positive regulation of ligase activity|,DNA binding|protein C-terminus binding|,10,0.5,3.79,10,1.1,13.7,0.7,16.4,16.4,0.092,0,0,0.3,1.5
ENSMUSG00000024191,BNIP1,BCL2/adenovirus E1B interacting protein 1,nuclear envelope|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|SNARE complex|intracellular membrane-bounded organelle|,transport|autophagy|apoptotic process|endoplasmic reticulum organization|protein transport|vesicle-mediated transport|endoplasmic reticulum membrane fusion|,SNAP receptor activity|,10,1.5,7.4,10,0.7,11.8,0.8,16.3,16.3,0.0927,0,0,0.4,1.8
ENSMUSG00000072582,PTRH2,peptidyl-tRNA hydrolase 2,mitochondrion|mitochondrion|cytosol|membrane|,negative regulation of gene expression|positive regulation of anoikis|negative regulation of anoikis|,aminoacyl-tRNA hydrolase activity|hydrolase activity|,10,0.6,10.6,10,0.5,6.06,0.5,16.1,16.1,0.0937,0,0,0.3,1
ENSMUSG00000000751,RPA1,replication protein A1,condensed chromosome|condensed nuclear chromosome|lateral element|male germ cell nucleus|nucleus|nucleus|DNA replication factor A complex|cytoplasm|actin cytoskeleton|PML body|,telomere maintenance|double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|in utero embryonic development|DNA replication|DNA repair|base-excision repair|nucleotide-excision repair|mismatch repair|DNA recombination|cellular response to DNA damage stimulus|meiotic nuclear division|positive regulation of cell proliferation|hemopoiesis|homeostasis of number of cells within a tissue|chromosome organization|,nucleic acid binding|DNA binding|chromatin binding|damaged DNA binding|single-stranded DNA binding|metal ion binding|,8,0.2,1.25,8,1.1,17,0.8,16.1,16.1,0.0937,0,0,0.3,1.7
ENSMUSG00000019850,TNFAIP3,"tumor necrosis factor, alpha-induced protein 3",nucleus|cytoplasm|cytoplasm|lysosome|centrosome|extracellular vesicular exosome|,B-1 B cell homeostasis|response to molecule of bacterial origin|response to molecule of bacterial origin|marginal zone B cell differentiation|negative regulation of granuloma formation|regulation of germinal center formation|regulation of immunoglobulin production|negative regulation of chronic inflammatory response|proteolysis|apoptotic process|inflammatory response|metabolic process|response to wounding|negative regulation of autophagy|protein deubiquitination|negative regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|response to muramyl dipeptide|negative regulation of interleukin-1 beta production|negative regulation of interleukin-2 production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|negative regulation of heterotypic cell-cell adhesion|negative regulation of toll-like receptor 3 signaling pathway|negative regulation of toll-like receptor 5 signaling pathway|protein K11-linked deubiquitination|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|regulation of innate immune response|positive regulation of protein catabolic process|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of innate immune response|negative regulation of smooth muscle cell proliferation|negative regulation of inflammatory response|negative regulation of inflammatory response|negative regulation of B cell activation|negative regulation of cell death|cellular response to hydrogen peroxide|negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway|negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway|protein K63-linked deubiquitination|protein K63-linked deubiquitination|protein K48-linked ubiquitination|protein K48-linked deubiquitination|cellular response to lipopolysaccharide|tolerance induction to lipopolysaccharide|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of hepatocyte proliferation|negative regulation of CD40 signaling pathway|negative regulation of endothelial cell apoptotic process|,"protease binding|DNA binding|catalytic activity|ubiquitin thiolesterase activity|ubiquitin-protein transferase activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|hydrolase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|kinase binding|ubiquitin binding|protein self-association|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,2.61,10,-0.9,16,-0.6,15.9,-15.9,0.0948,0,0,-1.4,-0.3
ENSMUSG00000003731,KPNA6,karyopherin (importin) alpha 6,intracellular|cell|nucleus|cytoplasm|membrane|,protein import into nucleus|transport|protein transport|positive regulation of transcription from RNA polymerase II promoter|maternal process involved in female pregnancy|,protein binding|protein transporter activity|,10,0.8,7.6,10,0.5,9.5,0.7,15.9,15.9,0.0948,0,0,0.3,1.2
ENSMUSG00000007029,VARS,valyl-tRNA synthetase,mitochondrion|,translation|tRNA aminoacylation for protein translation|valyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA editing activity|aminoacyl-tRNA ligase activity|valine-tRNA ligase activity|ATP binding|ligase activity|,10,-0.5,6.74,10,-1.7,15.1,-1.6,15.9,-15.9,0.0948,0,0,-3,0.6
ENSMUSG00000036835,PSENEN,presenilin enhancer 2 homolog (C. elegans),endoplasmic reticulum|Golgi apparatus|integral component of plasma membrane|membrane|integral component of membrane|,membrane protein ectodomain proteolysis|Notch signaling pathway|Notch receptor processing|protein processing|positive regulation of catalytic activity|,protein binding|,10,-0.9,6.34,10,0.8,17.3,0.7,15.8,15.8,0.0955,0,0,0.4,1.4
ENSMUSG00000039128,CDC123,cell division cycle 123,cytoplasm|,cell cycle|cell division|,molecular_function|,9,1,13.7,9,0.6,3.53,0.9,15.7,15.7,0.096,0,0,0.4,1.7
ENSMUSG00000018697,AATF,apoptosis antagonizing transcription factor,nucleus|nucleus|nucleolus|nucleolus|cytoplasm|cytoplasm|Golgi apparatus|centrosome|focal adhesion|,"cell adhesion|regulation of mitotic cell cycle|negative regulation of superoxide anion generation|embryonic cleavage|ribosome biogenesis|negative regulation of amyloid precursor protein biosynthetic process|negative regulation of apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of reactive oxygen species metabolic process|",sequence-specific DNA binding transcription factor activity|protein binding|protein domain specific binding|leucine zipper domain binding|poly(A) RNA binding|tau protein binding|,9,1,10.4,9,1,5.69,1,15.7,15.7,0.096,0,0,0.6,1.9
ENSMUSG00000024382,ERCC3,"excision repair cross-complementing rodent repair deficiency, complementation group 3",core TFIIH complex|nucleus|holo TFIIH complex|,"nucleotide-excision repair, DNA duplex unwinding|ATP catabolic process|DNA topological change|DNA repair|transcription-coupled nucleotide-excision repair|nucleotide-excision repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|apoptotic process|cellular response to DNA damage stimulus|response to oxidative stress|protein localization|response to UV|UV protection|nucleotide-excision repair, DNA incision|hair cell differentiation|positive regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|regulation of mitotic cell cycle phase transition|",nucleotide binding|DNA binding|ATP-dependent DNA helicase activity|helicase activity|protein kinase activity|ATP binding|GTP binding|protein C-terminus binding|DNA-dependent ATPase activity|RNA polymerase II carboxy-terminal domain kinase activity|RNA polymerase II carboxy-terminal domain kinase activity|hydrolase activity|ATPase activity|dATP binding|peptide binding|3'-5' DNA helicase activity|protein N-terminus binding|,10,0.7,11.8,10,1.1,5.24,0.8,15.7,15.7,0.096,0,0,0.4,1.5
ENSMUSG00000025234,ARIH1,ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila),cytoplasm|,ubiquitin-dependent protein catabolic process|protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,11.4,10,-0.5,4.71,-0.5,15.7,-15.7,0.096,0,0,-1,-0.3
ENSMUSG00000038641,AKR1D1,"aldo-keto reductase family 1, member D1",cytoplasm|cytosol|extracellular vesicular exosome|,lipid metabolic process|bile acid biosynthetic process|cholesterol catabolic process|digestion|steroid metabolic process|C21-steroid hormone metabolic process|androgen metabolic process|lipid catabolic process|bile acid catabolic process|oxidation-reduction process|,oxidoreductase activity|3-oxo-5-beta-steroid 4-dehydrogenase activity|delta4-3-oxosteroid 5beta-reductase activity|,10,0.2,1.33,10,1.3,17.7,1.3,15.6,15.6,0.0966,0,0,0.3,2
ENSMUSG00000029344,TPST2,protein-tyrosine sulfotransferase 2,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,peptidyl-tyrosine sulfation|fusion of sperm to egg plasma membrane|prevention of polyspermy|,protein-tyrosine sulfotransferase activity|transferase activity|,10,0.4,4.85,10,0.5,11.4,0.5,15.6,15.6,0.0966,0,0,0.2,0.8
ENSMUSG00000021235,COQ6,coenzyme Q6 homolog (yeast),mitochondrion|mitochondrion|Golgi apparatus|cell projection|,ubiquinone biosynthetic process|biological_process|metabolic process|oxidation-reduction process|,"molecular_function|monooxygenase activity|3-(3-hydroxyphenyl)propionate hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen|4-chlorobenzaldehyde oxidase activity|3,5-xylenol methylhydroxylase activity|phenylacetate hydroxylase activity|4-nitrophenol 4-monooxygenase activity|dimethyl sulfide monooxygenase activity|alpha-pinene monooxygenase [NADH] activity|phenanthrene 9,10-monooxygenase activity|1-hydroxy-2-naphthoate hydroxylase activity|toluene 4-monooxygenase activity|xylene monooxygenase activity|dibenzothiophene monooxygenase activity|6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|chlorophenol 4-monooxygenase activity|carbon disulfide oxygenase activity|toluene 2-monooxygenase activity|1-hydroxy-2-oxolimonene 1,2-monooxygenase activity|phenanthrene 1,2-monooxygenase activity|tetrahydrofuran hydroxylase activity|styrene monooxygenase activity|toluene-4-sulfonate monooxygenase activity|toluene-sulfonate methyl-monooxygenase activity|3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|2-hydroxy-phenylacetate hydroxylase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity|phenanthrene 3,4-monooxygenase activity|toluene 3-monooxygenase activity|4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity|limonene monooxygenase activity|2-methylnaphthalene hydroxylase activity|1-methylnaphthalene hydroxylase activity|bisphenol A hydroxylase A activity|salicylate 5-hydroxylase activity|isobutylamine N-hydroxylase activity|branched-chain dodecylbenzene sulfonate monooxygenase activity|3-HSA hydroxylase activity|4-hydroxypyridine-3-hydroxylase activity|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity|6-hydroxynicotinate 3-monooxygenase activity|flavin adenine dinucleotide binding|tocotrienol omega-hydroxylase activity|thalianol hydroxylase activity|",10,0.4,5.67,10,0.6,10.8,0.5,15.6,15.6,0.0966,0,0,0.3,1
ENSMUSG00000041958,PIGS,"phosphatidylinositol glycan anchor biosynthesis, class S",endoplasmic reticulum|membrane|membrane|integral component of membrane|GPI-anchor transamidase complex|,GPI anchor biosynthetic process|attachment of GPI anchor to protein|,GPI-anchor transamidase activity|,10,0.5,6.65,10,0.5,9.23,0.5,15.5,15.5,0.0972,0,0,0.3,0.9
ENSMUSG00000058624,GDA,guanine deaminase,extracellular vesicular exosome|,guanine catabolic process|,"protein binding|zinc ion binding|guanine deaminase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|metal ion binding|",10,1.3,5.01,10,1.3,10.8,1.3,15.5,15.5,0.0972,0,0,0.9,2
ENSMUSG00000038160,ATG5,autophagy related 5,cytoplasm|autophagic vacuole|autophagic vacuole|axoneme|membrane|pre-autophagosomal structure membrane|ER-mitochondrion membrane contact site|,autophagic vacuole assembly|blood vessel remodeling|immune system process|regulation of cytokine secretion involved in immune response|autophagy|apoptotic process|response to fungus|negative regulation of protein ubiquitination|negative stranded viral RNA replication|vasodilation|response to drug|negative regulation of apoptotic process|post-translational protein modification|innate immune response|otolith development|regulation of release of sequestered calcium ion into cytosol|ventricular cardiac muscle cell development|heart contraction|positive regulation of mucus secretion|regulation of cilium assembly|regulation of reactive oxygen species metabolic process|,protein binding|,10,-0.5,6.99,10,-1,9.69,-0.5,15.3,-15.3,0.0983,0,0,-1.3,-0.2
ENSMUSG00000027620,RBM39,RNA binding motif protein 39,nucleus|nucleus|microtubule organizing center|microtubule cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|regulation of RNA biosynthetic process|",nucleotide binding|nucleic acid binding|transcription coactivator activity|RNA binding|protein binding|poly(A) RNA binding|,8,0.7,7.24,8,0.6,8.63,0.6,15.1,15.1,0.0995,0,0,0.3,1.2
ENSMUSG00000064179,TNNT1,"troponin T1, skeletal, slow",troponin complex|,skeletal muscle contraction|regulation of muscle contraction|slow-twitch skeletal muscle fiber contraction|negative regulation of muscle contraction|,tropomyosin binding|troponin T binding|,10,1,12.3,10,1.1,3.02,1.1,14.9,14.9,0.101,0,0,0.7,1.9
ENSMUSG00000025583,RPTOR,"regulatory associated protein of MTOR, complex 1",cytoplasm|lysosome|lysosomal membrane|dendrite|TORC1 complex|neuronal cell body|,positive regulation of endothelial cell proliferation|regulation of cell size|cell growth|cellular response to nutrient levels|TOR signaling|positive regulation of TOR signaling|regulation of phosphorylation|positive regulation of transcription from RNA polymerase III promoter|cellular response to amino acid stimulus|positive regulation of protein serine/threonine kinase activity|,RNA polymerase III type 1 promoter DNA binding|RNA polymerase III type 2 promoter DNA binding|RNA polymerase III type 3 promoter DNA binding|TFIIIC-class transcription factor binding|protein binding|protein kinase binding|protein complex binding|14-3-3 protein binding|,10,0.7,9.8,10,0.6,5.73,0.7,14.9,14.9,0.101,0,0,0.4,1.3
ENSMUSG00000074781,UBE2N,ubiquitin-conjugating enzyme E2N,ubiquitin ligase complex|nucleus|nucleus|cytoplasm|UBC13-MMS2 complex|UBC13-UEV1A complex|protein complex|extracellular vesicular exosome|,double-strand break repair via homologous recombination|DNA double-strand break processing|DNA repair|postreplication repair|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|protein ubiquitination|protein ubiquitination|histone ubiquitination|positive regulation of histone modification|regulation of histone ubiquitination|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of DNA repair|T cell receptor signaling pathway|T cell receptor signaling pathway|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of ubiquitin-protein transferase activity|protein K63-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|ubiquitin binding|poly(A) RNA binding|,9,0.8,9.6,7,0.9,5.61,0.8,14.7,14.7,0.102,0,0,0.4,1.5
ENSMUSG00000031701,DNAJA2,"DnaJ (Hsp40) homolog, subfamily A, member 2",nucleus|cytosol|membrane|extracellular vesicular exosome|,protein folding|response to heat|protein refolding|,glycoprotein binding|ATP binding|heat shock protein binding|metal ion binding|unfolded protein binding|chaperone binding|,10,1,11.2,10,0.7,5.22,0.9,14.5,14.5,0.103,0,0,0.4,1.6
ENSMUSG00000054823,WHSC1L1,Wolf-Hirschhorn syndrome candidate 1-like 1 (human),nucleus|chromosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone methylation|peptidyl-lysine methylation|methylation|histone lysine methylation|",methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|metal ion binding|,10,-0.9,7.12,10,-0.5,8.58,-0.5,14.5,-14.5,0.103,0,0,-1.1,-0.2
ENSMUSG00000068220,LGALS1,"lectin, galactose binding, soluble 1",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|intracellular|nucleus|cytoplasm|cell surface|extracellular matrix|extracellular vesicular exosome|,plasma cell differentiation|apoptotic process|heterophilic cell-cell adhesion|signal transduction|negative regulation of cell-substrate adhesion|negative regulation of neuron projection development|T cell costimulation|positive regulation of erythrocyte aggregation|positive regulation of I-kappaB kinase/NF-kappaB signaling|myoblast differentiation|,glycoprotein binding|signal transducer activity|protein binding|galactose binding|galactoside binding|carbohydrate binding|lactose binding|protein homodimerization activity|laminin binding|poly(A) RNA binding|,10,0.6,13.2,10,1,2.16,0.6,14.5,14.5,0.103,0,0,0.4,1.3
ENSMUSG00000023456,TPI1,triosephosphate isomerase 1,extracellular space|nucleus|extracellular vesicular exosome|,glucose metabolic process|gluconeogenesis|glycolytic process|pentose-phosphate shunt|multicellular organismal development|metabolic process|embryo development|glyceraldehyde-3-phosphate metabolic process|,catalytic activity|triose-phosphate isomerase activity|triose-phosphate isomerase activity|triose-phosphate isomerase activity|isomerase activity|,8,0.4,3.07,8,1,13.6,1,14.4,14.4,0.104,0,0,0.5,1.7
ENSMUSG00000022150,DAB2,"disabled 2, mitogen-responsive phosphoprotein",nucleus|nucleolus|cytoplasm|plasma membrane|plasma membrane|coated pit|membrane|apical plasma membrane|clathrin coat of coated pit|clathrin-coated vesicle membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|transforming growth factor beta receptor homodimeric complex|extracellular vesicular exosome|,"cell morphogenesis involved in differentiation|in utero embryonic development|positive regulation of receptor recycling|positive regulation of protein phosphorylation|transport|endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|pinocytosis|apoptotic process|activation of JUN kinase activity|multicellular organismal development|endoderm development|excretion|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of neuron projection development|protein transport|Wnt signaling pathway|cell differentiation|negative regulation of cell growth|positive regulation of cell migration|positive regulation of transforming growth factor beta receptor signaling pathway|negative regulation of protein binding|positive regulation of aldosterone biosynthetic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of transcription elongation from RNA polymerase II promoter|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of cell adhesion|positive regulation of cell adhesion|positive regulation of endocytosis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|clathrin coat assembly|clathrin coat assembly|response to steroid hormone|negative regulation of epithelial cell proliferation|positive regulation of SMAD protein import into nucleus|negative regulation of androgen receptor signaling pathway|negative regulation of ERK1 and ERK2 cascade|cellular response to epidermal growth factor stimulus|cellular response to transforming growth factor beta stimulus|negative regulation of canonical Wnt signaling pathway|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of Wnt signaling pathway, planar cell polarity pathway|regulation of Rho-dependent protein serine/threonine kinase activity|positive regulation of clathrin-mediated endocytosis|positive regulation of clathrin-mediated endocytosis|positive regulation of early endosome to late endosome transport|positive regulation of aldosterone secretion|positive regulation of integrin-mediated signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|","integrin binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|protein C-terminus binding|clathrin binding|phosphatidylinositol binding|AP-2 adaptor complex binding|clathrin adaptor activity|clathrin adaptor activity|cargo receptor activity|cargo receptor activity|SMAD binding|",10,0.1,0.0902,10,1.3,17.1,1.2,14.3,14.3,0.105,0,0,0.3,1.9
ENSMUSG00000028932,PSMC2,"proteasome (prosome, macropain) 26S subunit, ATPase 2",proteasome complex|cytoplasmic mRNA processing body|nucleus|cytoplasm|membrane|proteasome accessory complex|,osteoblast differentiation|ATP catabolic process|ubiquitin-dependent protein catabolic process|protein catabolic process|,nucleotide binding|protein binding|ATP binding|hydrolase activity|ATPase activity|TBP-class protein binding|,10,1,11.2,9,0.5,4.64,0.8,14.1,14.1,0.106,0,0,0.2,1.5
ENSMUSG00000027823,GMPS,guanine monophosphate synthetase,cytoplasm|cytosol|,purine nucleotide biosynthetic process|GMP biosynthetic process|glutamine metabolic process|,nucleotide binding|GMP synthase activity|GMP synthase (glutamine-hydrolyzing) activity|ATP binding|pyrophosphatase activity|ligase activity|,9,1.1,11.9,9,0.4,5.84,0.8,14,14,0.107,0,0,0.3,1.6
ENSMUSG00000028826,TMEM57,transmembrane protein 57,nucleus|membrane|integral component of membrane|axon|nuclear membrane|cell projection|neuron projection|neuron projection terminus|synapse|,biological_process|,molecular_function|,10,-0.6,12.4,10,0.7,3.95,-0.5,13.9,-13.9,0.107,0,0,-1,-0.3
ENSMUSG00000024853,SF3B2,"splicing factor 3b, subunit 2",nucleus|spliceosomal complex|U12-type spliceosomal complex|catalytic step 2 spliceosome|,biological_process|,protein binding|poly(A) RNA binding|,10,0.5,6.98,9,0.6,7.42,0.5,13.8,13.8,0.108,0,0,0.3,1
ENSMUSG00000052833,SAE1,SUMO1 activating enzyme subunit 1,nucleus|nucleus|cytosol|intracellular membrane-bounded organelle|,cellular protein modification process|regulation of mitotic cell cycle|protein sumoylation|protein sumoylation|SMT3-dependent protein catabolic process|,catalytic activity|protein C-terminus binding|small protein activating enzyme activity|ligase activity|SUMO activating enzyme activity|SUMO activating enzyme activity|ATP-dependent protein binding|protein heterodimerization activity|,10,0.9,7.53,9,0.6,7.88,0.8,13.5,13.5,0.11,0,0,0.4,1.5
ENSMUSG00000056501,CEBPB,"CCAAT/enhancer binding protein (C/EBP), beta","condensed chromosome, centromeric region|nuclear chromatin|nucleus|nucleus|cytoplasm|nuclear matrix|nuclear matrix|","embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell differentiation|neuron differentiation|response to lipopolysaccharide|mammary gland epithelial cell proliferation|response to endoplasmic reticulum stress|negative regulation of neuron apoptotic process|regulation of interleukin-6 biosynthetic process|fat cell differentiation|fat cell differentiation|positive regulation of fat cell differentiation|positive regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|brown fat cell differentiation|mammary gland epithelial cell differentiation|regulation of transcription involved in cell fate commitment|cellular response to amino acid stimulus|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|glucocorticoid receptor binding|protein homodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding|protein heterodimerization activity|protein heterodimerization activity|,10,0.3,4.37,10,0.5,9.94,0.5,13.5,13.5,0.11,0,0,0.2,0.8
ENSMUSG00000032254,KIF23,kinesin family member 23,nucleus|cytoplasm|centrosome|spindle|cytoskeleton|kinesin complex|microtubule|midbody|intercellular bridge|mitotic spindle|centralspindlin complex|,cytokinesis|microtubule-based movement|cell cycle|mitotic nuclear division|positive regulation of cytokinesis|spindle midzone assembly involved in mitosis|cell division|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,9,0.6,9.05,10,0.6,4.69,0.6,13.4,13.4,0.111,0,0,0.3,1.3
ENSMUSG00000032485,SCAP,SREBF chaperone,endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|protein complex|,response to hypoxia|lipid metabolic process|steroid metabolic process|cholesterol metabolic process|regulation of fatty acid metabolic process|response to insulin|SREBP signaling pathway|regulation of fatty acid biosynthetic process|regulation of cholesterol biosynthetic process|,protein binding|cholesterol binding|protein complex binding|,10,0.5,6.5,10,0.6,7.01,0.5,13,13,0.114,0,0,0.2,0.9
ENSMUSG00000066149,CDC26,cell division cycle 26,nucleus|anaphase-promoting complex|,cell cycle|mitotic nuclear division|regulation of mitotic metaphase/anaphase transition|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell division|protein K11-linked ubiquitination|,molecular_function|,10,0.6,4.49,10,1.3,11.1,0.9,13,13,0.114,0,0,0.3,1.9
ENSMUSG00000068600,HEMT1,hematopoietic cell transcript 1,cellular_component|,biological_process|,molecular_function|,10,1.5,5.88,10,0.6,10.1,0.7,12.7,12.7,0.117,0,0,0.3,1.9
ENSMUSG00000030096,SLC6A6,"solute carrier family 6 (neurotransmitter transporter, taurine), member 6",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,beta-alanine transport|amino acid transmembrane transport|transport|neurotransmitter transport|taurine transport|taurine transport|taurine transport|organic acid transport|sodium ion transmembrane transport|,beta-alanine transmembrane transporter activity|neurotransmitter:sodium symporter activity|taurine transmembrane transporter activity|taurine:sodium symporter activity|symporter activity|taurine binding|,10,0.5,5.9,10,0.4,7.12,0.5,12.6,12.6,0.118,0,0,0.2,0.9
ENSMUSG00000017144,RND3,Rho family GTPase 3,intracellular|Golgi apparatus|membrane|extracellular vesicular exosome|,small GTPase mediated signal transduction|,nucleotide binding|protein binding|GTP binding|,10,0,0,10,1.3,15.6,1.3,12.4,12.4,0.12,0,0,0.3,2
ENSMUSG00000033066,GAS7,growth arrest specific 7,ruffle|cytoplasm|actin filament|,multicellular organismal development|nervous system development|regulation of cell shape|actin filament polymerization|cell differentiation|neuron differentiation|neuron projection morphogenesis|actin filament bundle assembly|,actin filament binding|,10,0.5,5.36,10,0.8,8.17,0.7,12.3,12.3,0.121,0,0,0.3,1.2
ENSMUSG00000031756,CENPN,centromere protein N,"chromosome, centromeric region|kinetochore|nucleus|chromosome|",chromosome segregation|mitotic nuclear division|biological_process|centromere complex assembly|,molecular_function|,10,1.1,13.9,10,0.2,0.992,1.1,12.2,12.2,0.122,0,0,0.4,2
ENSMUSG00000034575,PAPD7,PAP associated domain containing 7,nucleus|cytoplasm|,DNA replication|cell cycle|mitotic nuclear division|response to drug|cell division|,molecular_function|DNA binding|DNA-directed DNA polymerase activity|polynucleotide adenylyltransferase activity|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,0.3,3.03,10,0.5,10.4,0.4,12.2,12.2,0.122,0,0,0.2,0.8
ENSMUSG00000046010,ZFP830,zinc finger protein 830,nucleus|nucleus|nucleus|chromosome|cytoplasm|nuclear speck|,blastocyst growth|cell cycle|mitotic nuclear division|multicellular organismal development|nuclear cell cycle DNA replication|mitotic DNA damage checkpoint|chromosome organization|cell division|intestinal epithelial structure maintenance|,molecular_function|metal ion binding|,10,0.6,6.19,10,0.8,6.5,0.7,12.2,12.2,0.122,0,0,0.3,1.2
ENSMUSG00000031016,WEE1,WEE 1 homolog 1 (S. pombe),nucleus|cytoplasm|,microtubule cytoskeleton organization|protein phosphorylation|cell cycle|mitotic nuclear division|phosphorylation|peptidyl-tyrosine phosphorylation|establishment of cell polarity|neuron projection morphogenesis|neuron projection morphogenesis|cell division|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.5,6.62,10,-0.8,12.3,0.7,12.1,12.1,0.123,0,0,-1.1,2
ENSMUSG00000023826,PARK2,"Parkinson disease (autosomal recessive, juvenile) 2, parkin",Golgi membrane|ubiquitin ligase complex|intracellular|nucleus|cytoplasm|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|synaptic vesicle|postsynaptic density|membrane|aggresome|cell junction|cytoplasmic vesicle|cell projection|neuron projection|protein complex|membrane raft|synapse|postsynaptic membrane|perinuclear region of cytoplasm|,"protein polyubiquitination|mitochondrion degradation|negative regulation of protein phosphorylation|synaptic transmission, dopaminergic|startle response|transcription, DNA-templated|regulation of transcription, DNA-templated|ubiquitin-dependent protein catabolic process|protein monoubiquitination|autophagy|response to unfolded protein|learning|locomotory behavior|cell death|adult locomotory behavior|regulation of autophagy|protein ubiquitination|protein ubiquitination|protein metabolic process|negative regulation of actin filament bundle assembly|negative regulation of glucokinase activity|synaptic transmission, glutamatergic|norepinephrine metabolic process|dopamine metabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of neuron apoptotic process|cellular protein catabolic process|negative regulation of insulin secretion|regulation of neurotransmitter secretion|regulation of synaptic transmission|dopamine uptake involved in synaptic transmission|protein autoubiquitination|negative regulation of cell death|protein K63-linked ubiquitination|aggresome assembly|protein K48-linked ubiquitination|neuron death|negative regulation of release of cytochrome c from mitochondria|negative regulation of neuron death|regulation of reactive oxygen species metabolic process|","ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|kinase binding|protein kinase binding|PDZ domain binding|ubiquitin protein ligase binding|protein complex binding|identical protein binding|ubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|chaperone binding|ubiquitin protein ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|ubiquitin-specific protease binding|",10,0,0,10,1.3,15.5,1.3,12.1,12.1,0.123,0,0,0.4,2
ENSMUSG00000012443,KIF11,kinesin family member 11,spindle pole|cytoplasm|spindle|cytoskeleton|kinesin complex|microtubule|spindle microtubule|membrane|mitotic spindle|,microtubule-based movement|cell cycle|spindle organization|mitotic nuclear division|mitotic centrosome separation|cell division|spindle assembly involved in mitosis|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|protein kinase binding|protein complex binding|,7,-1,13.7,9,-0.2,0.384,-0.9,11.8,-11.8,0.126,0,0,-1.7,-0.4
ENSMUSG00000024603,DCTN4,dynactin 4,cytoplasm|centrosome|cytoskeleton|cytoplasmic dynein complex|dynactin complex|,biological_process|,protein N-terminus binding|,10,0.5,5.47,10,0.6,6.6,0.6,11.6,11.6,0.128,0,0,0.2,1
ENSMUSG00000034330,PLCG2,"phospholipase C, gamma 2",intracellular|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,follicular B cell differentiation|lipid metabolic process|phosphatidylinositol biosynthetic process|signal transduction|positive regulation of cytosolic calcium ion concentration|phospholipid catabolic process|regulation of gene expression|lipid catabolic process|B cell differentiation|response to magnesium ion|activation of store-operated calcium channel activity|response to lipopolysaccharide|inositol trisphosphate biosynthetic process|response to ATP|intracellular signal transduction|negative regulation of programmed cell death|T cell receptor signaling pathway|B cell receptor signaling pathway|release of sequestered calcium ion into cytosol|release of sequestered calcium ion into cytosol|,phosphatidylinositol phospholipase C activity|phospholipase C activity|signal transducer activity|protein binding|phosphoric diester hydrolase activity|hydrolase activity|,10,0.4,3.6,10,0.9,10.4,0.8,11.5,11.5,0.129,0,0,0.3,1.3
ENSMUSG00000031450,GRK1,G protein-coupled receptor kinase 1,membrane|,protein phosphorylation|signal transduction|visual perception|photoreceptor cell morphogenesis|response to light stimulus|phosphorylation|regulation of rhodopsin mediated signaling pathway|termination of G-protein coupled receptor signaling pathway|positive regulation of phosphorylation|negative regulation of apoptotic process|protein autophosphorylation|response to stimulus|post-embryonic retina morphogenesis in camera-type eye|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|G-protein coupled receptor kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|rhodopsin kinase activity|",10,-0.1,0.0518,10,1.3,14.6,1.3,11.4,11.4,0.13,0,0,0.4,2
ENSMUSG00000007880,ARID1A,AT rich interactive domain 1A (SWI-like),nuclear chromatin|nuclear chromatin|intracellular|nucleus|SWI/SNF complex|SWI/SNF complex|npBAF complex|nBAF complex|BAF-type complex|,"negative regulation of transcription from RNA polymerase II promoter|neural tube closure|cardiac chamber development|optic cup formation involved in camera-type eye development|chromatin organization|nucleosome disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|chromatin modification|intracellular estrogen receptor signaling pathway|androgen receptor signaling pathway|forebrain development|glucocorticoid receptor signaling pathway|ATP-dependent chromatin remodeling|positive regulation of transcription, DNA-templated|placenta blood vessel development|",DNA binding|protein binding|ligand-dependent nuclear receptor binding|nucleosome binding|,10,0.6,5.59,10,0.4,6.55,0.5,11.4,11.4,0.13,0,0,0.2,1
ENSMUSG00000033020,POLR2F,polymerase (RNA) II (DNA directed) polypeptide F,"nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase III complex|nucleolus|DNA-directed RNA polymerase I complex|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase I activity|RNA polymerase II activity|RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|,10,0.3,1.84,10,0.6,10.7,0.5,11.3,11.3,0.131,0,0,0.2,1
ENSMUSG00000044894,UQCRQ,"ubiquinol-cytochrome c reductase, complex III subunit VII",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|ubiquinol-cytochrome-c reductase activity|,10,0.1,0.35,10,0.5,12.2,0.5,11.2,11.2,0.132,0,0,0.2,1
ENSMUSG00000037742,EEF1A1,eukaryotic translation elongation factor 1 alpha 1,extracellular space|nucleus|nucleolus|cytoplasm|cytoplasm|plasma membrane|membrane|extracellular vesicular exosome|,translation|translational elongation|protein homooligomerization|cellular response to epidermal growth factor stimulus|,nucleotide binding|mRNA binding|translation elongation factor activity|GTPase activity|protein binding|GTP binding|protein kinase binding|poly(A) RNA binding|,8,-0.9,6.22,8,0.5,6.39,0.7,11,11,0.134,0,0,-1.4,2
ENSMUSG00000036199,NDUFA13,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13",nucleus|nucleoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain|mitochondrial respiratory chain complex I|mitochondrial membrane|extracellular vesicular exosome|,"negative regulation of cell growth|protein import into mitochondrial inner membrane|negative regulation of transcription, DNA-templated|oxidation-reduction process|reactive oxygen species metabolic process|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway|",NADH dehydrogenase activity|ATP binding|NADH dehydrogenase (ubiquinone) activity|,10,0.7,5.47,10,0.5,6.55,0.5,11,11,0.134,0,0,0.3,1.1
ENSMUSG00000045948,MRPS12,mitochondrial ribosomal protein S12,intracellular|mitochondrion|ribosome|small ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,0.6,5.38,10,0.4,6.23,0.5,10.9,10.9,0.136,0,0,0.2,1.1
ENSMUSG00000073489,IFI204,interferon activated gene 204,nucleus|nucleoplasm|nucleolus|cytoplasm|membrane|nuclear speck|,regulation of transcription from RNA polymerase II promoter|cellular response to interferon-beta|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of osteoblast differentiation|inner ear development|regulation of RNA biosynthetic process|,double-stranded DNA binding|double-stranded DNA binding|transcription cofactor activity|protein binding|transcription factor binding|poly(A) RNA binding|,10,0.4,6.46,10,0.5,4.97,0.4,10.9,10.9,0.136,0,0,0.2,1
ENSMUSG00000029681,BCL7B,B cell CLL/lymphoma 7B,cellular_component|,biological_process|,molecular_function|,10,0.9,8.64,10,0.3,4.28,0.3,10.9,10.9,0.136,0,0,0.1,1.3
ENSMUSG00000036977,ANAPC10,anaphase promoting complex subunit 10,anaphase-promoting complex|cytoplasm|,cell cycle|mitotic nuclear division|regulation of mitotic metaphase/anaphase transition|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell division|protein K11-linked ubiquitination|,molecular_function|,10,-1.5,1.09,10,0.7,13,0.6,10.8,10.8,0.137,0,0,0.2,1.5
ENSMUSG00000024401,TNF,tumor necrosis factor,phagocytic cup|extracellular region|extracellular space|extracellular space|intracellular|intracellular|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|secretory granule|membrane raft|membrane raft|recycling endosome|,"protein import into nucleus, translocation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|activation of MAPKKK activity|activation of MAPK activity|cell activation|positive regulation of cytokine production|regulation of protein phosphorylation|positive regulation of protein phosphorylation|negative regulation of L-glutamate transport|chronic inflammatory response to antigenic stimulus|negative regulation of cytokine secretion involved in immune response|positive regulation of chronic inflammatory response to antigenic stimulus|positive regulation of humoral immune response mediated by circulating immunoglobulin|glucose metabolic process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|transformed cell apoptotic process|transformed cell apoptotic process|defense response|inflammatory response|inflammatory response|inflammatory response|immune response|humoral immune response|signal transduction|JNK cascade|multicellular organismal development|cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|intrinsic apoptotic signaling pathway in response to DNA damage|response to virus|organ morphogenesis|positive regulation of gene expression|negative regulation of gene expression|negative regulation of alkaline phosphatase activity|calcium-mediated signaling|extracellular matrix organization|osteoclast differentiation|sequestering of triglyceride|positive regulation of protein complex assembly|positive regulation of fever generation|lipopolysaccharide-mediated signaling pathway|negative regulation of interleukin-6 production|positive regulation of chemokine production|positive regulation of interferon-gamma production|positive regulation of interleukin-18 production|positive regulation of interleukin-6 production|receptor biosynthetic process|positive regulation of peptidyl-serine phosphorylation|tumor necrosis factor-mediated signaling pathway|tumor necrosis factor-mediated signaling pathway|positive regulation of heterotypic cell-cell adhesion|regulation of cell proliferation|positive regulation of NF-kappaB import into nucleus|positive regulation of NF-kappaB import into nucleus|defense response to bacterium|positive regulation of apoptotic process|positive regulation of programmed cell death|regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of protein complex disassembly|positive regulation of protein complex disassembly|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of MAP kinase activity|protein kinase B signaling|positive regulation of JUN kinase activity|positive regulation of neuron apoptotic process|negative regulation of growth of symbiont in host|negative regulation of viral genome replication|positive regulation of chemokine biosynthetic process|cellular extravasation|positive regulation of interleukin-8 biosynthetic process|positive regulation of nitric oxide biosynthetic process|negative regulation of osteoblast differentiation|regulation of osteoclast differentiation|positive regulation of osteoclast differentiation|positive regulation of action potential|positive regulation of mitosis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of translational initiation by iron|negative regulation of glucose import|negative regulation of glucose import|positive regulation of JNK cascade|positive regulation of JNK cascade|positive regulation of smooth muscle cell proliferation|regulation of protein secretion|positive regulation of cytokine secretion|positive regulation of inflammatory response|regulation of insulin secretion|positive regulation of synaptic transmission|defense response to Gram-positive bacterium|leukocyte migration|leukocyte tethering or rolling|detection of mechanical stimulus involved in sensory perception of pain|negative regulation of lipid catabolic process|regulation of immunoglobulin secretion|positive regulation of membrane protein ectodomain proteolysis|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of protein transport|response to glucocorticoid|positive regulation of NFAT protein import into nucleus|positive regulation of hair follicle development|positive regulation of protein kinase B signaling|positive regulation of vitamin D biosynthetic process|positive regulation of calcidiol 1-monooxygenase activity|epithelial cell proliferation involved in salivary gland morphogenesis|regulation of branching involved in salivary gland morphogenesis|regulation of branching involved in salivary gland morphogenesis|negative regulation of branching involved in lung morphogenesis|cellular response to lipopolysaccharide|cellular response to amino acid stimulus|cellular response to nicotine|cellular response to organic cyclic compound|positive regulation of podosome assembly|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway|necroptotic signaling pathway|necroptotic signaling pathway|positive regulation of protein localization to cell surface|positive regulation of chemokine (C-X-C motif) ligand 2 production|regulation of reactive oxygen species metabolic process|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|",protease binding|protease binding|cytokine activity|cytokine activity|tumor necrosis factor receptor binding|tumor necrosis factor receptor binding|tumor necrosis factor receptor binding|tumor necrosis factor receptor binding|protein binding|identical protein binding|transcription regulatory region DNA binding|,10,-0.4,7.13,10,-0.5,4.07,-0.4,10.8,-10.8,0.137,0,0,-0.9,-0.2
ENSMUSG00000028309,RNF20,ring finger protein 20,ubiquitin ligase complex|nucleus|HULC complex|,"protein polyubiquitination|regulation of transcription, DNA-templated|ubiquitin-dependent protein catabolic process|histone monoubiquitination|chromatin modification|histone ubiquitination|negative regulation of cell migration|positive regulation of histone methylation|histone H2B ubiquitination|positive regulation of transcription, DNA-templated|","p53 binding|chromatin binding|transcription coactivator activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|histone binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.5,6.87,10,0.4,4.33,0.5,10.7,10.7,0.138,0,0,0.2,1
ENSMUSG00000072235,TUBA1A,"tubulin, alpha 1A",nucleus|cytoplasm|cytoskeleton|microtubule|cytoplasmic microtubule|cytoplasmic ribonucleoprotein granule|protein complex|extracellular vesicular exosome|,GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|protein binding|GTP binding|protein domain specific binding|,8,0.8,12.7,8,0,0,0.8,10.6,10.6,0.139,0,0,0.3,1.7
ENSMUSG00000024908,PPP6R3,"protein phosphatase 6, regulatory subunit 3",nucleus|cytoplasm|plasma membrane|,regulation of phosphoprotein phosphatase activity|,protein phosphatase binding|,10,0.6,9.07,10,0.3,2.5,0.5,10.6,10.6,0.139,0,0,0.2,1
ENSMUSG00000021120,PIGH,"phosphatidylinositol glycan anchor biosynthesis, class H",glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|cytoplasm|,biological_process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|phosphatidylinositol N-acetylglucosaminyltransferase activity|",10,0.2,1.34,10,0.6,11,0.5,10.6,10.6,0.139,0,0,0.2,1.1
ENSMUSG00000026024,ALS2,amyotrophic lateral sclerosis 2 (juvenile),ruffle|intracellular|cell|nucleus|cytoplasm|cytoplasm|early endosome|centrosome|centrosome|cytosol|postsynaptic density|membrane|lamellipodium|axon|dendrite|growth cone|vesicle|neuron projection|neuronal cell body|dendritic spine|intracellular membrane-bounded organelle|protein complex|,"behavioral fear response|receptor recycling|response to oxidative stress|endosome organization|lysosomal transport|axonogenesis|neuromuscular junction development|locomotory behavior|protein localization|cell death|vesicle organization|endosomal transport|Rac protein signal transduction|regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|synaptic transmission, glutamatergic|positive regulation of protein kinase activity|neuron projection morphogenesis|protein homooligomerization|positive regulation of protein serine/threonine kinase activity|",guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rab GTPase activator activity|protein binding|Rab guanyl-nucleotide exchange factor activity|Rab GTPase binding|Rac GTPase activator activity|Rac guanyl-nucleotide exchange factor activity|identical protein binding|protein homodimerization activity|protein serine/threonine kinase activator activity|Rac GTPase binding|,10,0.1,0.354,10,1.3,13.2,1.3,10.3,10.3,0.143,0,0,0.3,2
ENSMUSG00000051316,TAF7,"TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|transcription factor TFIID complex|cytoplasm|Golgi apparatus|positive transcription elongation factor complex b|transcription factor TFTC complex|MLL1 complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|negative regulation of protein kinase activity|intracellular estrogen receptor signaling pathway|negative regulation of histone acetylation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|transcription factor binding|histone acetyltransferase binding|histone acetyltransferase binding|vitamin D receptor binding|transcription regulatory region DNA binding|thyroid hormone receptor binding|,10,0.5,3.88,10,0.7,7.04,0.6,10.3,10.3,0.143,0,0,0.2,1.4
ENSMUSG00000032123,DPAGT1,dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase),endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,UDP-N-acetylglucosamine metabolic process|protein N-linked glycosylation|dolichol-linked oligosaccharide biosynthetic process|dolichol-linked oligosaccharide biosynthetic process|dolichol metabolic process|dolichol biosynthetic process|,"UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity|UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity|UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity|phospho-N-acetylmuramoyl-pentapeptide-transferase activity|transferase activity|transferase activity, transferring glycosyl groups|",8,1.6,2.4,8,0.9,10.2,1.2,10.3,10.3,0.143,0,0,0.5,2.5
ENSMUSG00000067873,HTATSF1,HIV TAT specific factor 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.4,3.91,10,1,8.84,0.9,10.3,10.3,0.143,0,0,0.3,1.7
ENSMUSG00000001134,UXT,ubiquitously expressed transcript,gamma-tubulin complex|gamma-tubulin complex|nucleus|nucleus|cytoplasm|centrosome|centrosome|microtubule organizing center|cytoskeleton|cytoskeleton|prefoldin complex|,"negative regulation of transcription from RNA polymerase II promoter|microtubule cytoskeleton organization|microtubule cytoskeleton organization|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein folding|centrosome organization|centrosome organization|",RNA polymerase II transcription corepressor activity|chromatin binding|beta-tubulin binding|beta-tubulin binding|unfolded protein binding|,10,0.6,12.7,10,-0.5,4.08,0.6,10.2,10.2,0.144,0,0,0.2,1.5
ENSMUSG00000032000,BIRC3,baculoviral IAP repeat-containing 3,nucleus|cytoplasm|protein complex|membrane raft|,apoptotic process|protein ubiquitination|positive regulation of protein ubiquitination|negative regulation of phosphorylation|regulation of apoptotic process|protein heterooligomerization|regulation of necroptotic process|negative regulation of necroptotic process|necroptotic process|negative regulation of reactive oxygen species metabolic process|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.7,5.63,10,-0.4,5.38,-0.5,10.2,-10.2,0.144,0,0,-1.2,-0.2
ENSMUSG00000030591,PSMD8,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 8",proteasome complex|nucleus|proteasome regulatory particle|proteasome accessory complex|extracellular vesicular exosome|,proteolysis|,molecular_function|,10,0.4,3.75,10,0.6,7.47,0.5,10.2,10.2,0.144,0,0,0.2,1
ENSMUSG00000058076,SDHC,"succinate dehydrogenase complex, subunit C, integral membrane protein",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|succinate dehydrogenase complex|,tricarboxylic acid cycle|transport|oxidation-reduction process|,"succinate dehydrogenase activity|electron carrier activity|oxidoreductase activity, acting on the CH-CH group of donors|metal ion binding|",10,0.9,9.56,10,0.3,2.26,0.3,9.76,9.76,0.15,0,0,0.2,1.7
ENSMUSG00000028149,RAP1GDS1,"RAP1, GTP-GDP dissociation stimulator 1",mitochondrion|endoplasmic reticulum|cytosol|extracellular vesicular exosome|,vascular smooth muscle contraction|myosin filament assembly|positive regulation of Rho GTPase activity|negative regulation of endoplasmic reticulum calcium ion concentration|positive regulation of mitochondrial calcium ion concentration|,molecular_function|,10,0.8,6.57,10,1.1,4.01,0.8,9.75,9.75,0.151,0,0,0.3,1.7
ENSMUSG00000059552,TRP53,transformation related protein 53,chromatin|chromatin|nuclear chromatin|intracellular|nucleus|nucleus|nucleoplasm|replication fork|transcription factor complex|transcription factor complex|transcription factor TFIID complex|nucleolus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrion|mitochondrial matrix|endoplasmic reticulum|cytosol|cytosol|nuclear matrix|nuclear body|PML body|protein complex|,"protein import into nucleus, translocation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|DNA strand renaturation|in utero embryonic development|somitogenesis|release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|T cell proliferation involved in immune response|B cell lineage commitment|T cell lineage commitment|positive regulation of leukocyte migration|response to ischemia|nucleotide-excision repair|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein complex assembly|apoptotic process|apoptotic process|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|response to oxidative stress|response to oxidative stress|ER overload response|cell cycle|cell cycle arrest|transforming growth factor beta receptor signaling pathway|multicellular organismal development|gastrulation|negative regulation of neuroblast proliferation|central nervous system development|cell aging|cell aging|protein localization|negative regulation of DNA replication|negative regulation of DNA replication|negative regulation of cell proliferation|negative regulation of cell proliferation|determination of adult lifespan|rRNA transcription|response to UV|response to UV|response to salt stress|embryo development ending in birth or egg hatching|response to X-ray|response to gamma radiation|response to gamma radiation|response to gamma radiation|positive regulation of cardiac muscle cell apoptotic process|programmed cell death|cerebellum development|negative regulation of cell growth|DNA damage response, signal transduction by p53 class mediator|DNA damage response, signal transduction by p53 class mediator|DNA damage response, signal transduction by p53 class mediator|negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of histone deacetylation|chromatin assembly|mitotic G1 DNA damage checkpoint|mitotic G1 DNA damage checkpoint|positive regulation of protein oligomerization|T cell differentiation in thymus|regulation of tissue remodeling|cellular protein localization|cellular response to UV|multicellular organism growth|positive regulation of mitochondrial membrane permeability|regulation of cell proliferation|regulation of cell proliferation|cellular response to glucose starvation|response to drug|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of fibroblast proliferation|negative regulation of fibroblast proliferation|embryonic organ development|negative regulation of smooth muscle cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|regulation of catalytic activity|protein tetramerization|chromosome organization|neuron apoptotic process|neuron apoptotic process|regulation of intracellular pH|regulation of cell cycle|regulation of cell cycle|regulation of thymocyte apoptotic process|positive regulation of thymocyte apoptotic process|necroptotic process|positive regulation of cell cycle arrest|cellular response to ionizing radiation|cellular response to ionizing radiation|mitotic cell cycle arrest|intrinsic apoptotic signaling pathway by p53 class mediator|intrinsic apoptotic signaling pathway by p53 class mediator|intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of release of cytochrome c from mitochondria|positive regulation of cell aging|replicative senescence|oxidative stress-induced premature senescence|oligodendrocyte apoptotic process|negative regulation of macromitophagy|regulation of mitochondrial membrane permeability involved in apoptotic process|negative regulation of DNA biosynthetic process|negative regulation of reactive oxygen species metabolic process|positive regulation of reactive oxygen species metabolic process|positive regulation of intrinsic apoptotic signaling pathway|",RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding|transcription cofactor binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|protease binding|p53 binding|DNA binding|DNA binding|chromatin binding|chromatin binding|damaged DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|copper ion binding|protein binding|ATP binding|protein C-terminus binding|transcription factor binding|enzyme binding|protein kinase binding|protein phosphatase binding|receptor tyrosine kinase binding|ubiquitin protein ligase binding|histone deacetylase regulator activity|histone acetyltransferase binding|identical protein binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|protein heterodimerization activity|protein N-terminus binding|chaperone binding|protein phosphatase 2A binding|MDM2/MDM4 family protein binding|,10,-0.5,6.65,10,-0.3,4.01,-0.3,9.69,-9.69,0.151,0,0,-0.8,-0.1
ENSMUSG00000025856,PDGFA,"platelet derived growth factor, alpha",extracellular region|extracellular space|extracellular space|microvillus|cell surface|membrane|,angiogenesis|hair follicle development|positive regulation of mesenchymal cell proliferation|multicellular organismal development|blood coagulation|positive regulation of cell proliferation|positive regulation of cell proliferation|response to wounding|organ morphogenesis|organ morphogenesis|negative regulation of phosphatidylinositol biosynthetic process|negative regulation of platelet activation|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of phosphatidylinositol 3-kinase signaling|regulation of smooth muscle cell migration|cell projection assembly|actin cytoskeleton organization|positive regulation of cell migration|positive regulation of cell migration|positive regulation of protein autophosphorylation|positive regulation of protein autophosphorylation|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway|positive regulation of MAP kinase activity|positive regulation of MAP kinase activity|positive regulation of MAPK cascade|skin development|positive regulation of DNA replication|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|positive regulation of fibroblast proliferation|lung alveolus development|digestive tract development|regulation of peptidyl-tyrosine phosphorylation|negative chemotaxis|positive regulation of cell division|positive regulation of protein kinase B signaling|regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|,platelet-derived growth factor receptor binding|platelet-derived growth factor receptor binding|platelet-derived growth factor receptor binding|collagen binding|growth factor activity|protein homodimerization activity|protein heterodimerization activity|platelet-derived growth factor binding|,10,-1,2.95,10,-1.2,7.24,-1.1,9.62,-9.62,0.152,0,0,-2,-0.6
ENSMUSG00000026083,EIF5B,eukaryotic translation initiation factor 5B,cellular_component|cytoplasm|,translation|translational initiation|regulation of translational initiation|,nucleotide binding|translation initiation factor activity|GTPase activity|GTP binding|poly(A) RNA binding|,10,0.5,9.17,10,0.2,1.59,0.4,9.6,9.6,0.153,0,0,0.1,0.9
ENSMUSG00000049252,LRP1B,low density lipoprotein-related protein 1B (deleted in tumors),membrane|integral component of membrane|receptor complex|,endocytosis|receptor-mediated endocytosis|,low-density lipoprotein receptor activity|calcium ion binding|protein binding|,9,-0.5,1.16,9,0.7,11.6,0.6,9.59,9.59,0.153,0,0,0.2,1.5
ENSMUSG00000064128,CENPJ,centromere protein J,cytoplasm|centrosome|centriole|cytoskeleton|microtubule|,centriole replication|astral microtubule nucleation|positive regulation of JAK-STAT cascade|regulation of centriole replication|microtubule polymerization|regulation of RNA biosynthetic process|,transcription coactivator activity|protein binding|tubulin binding|protein kinase binding|protein domain specific binding|gamma-tubulin binding|,10,0.4,3.39,10,0.6,6.89,0.6,9.27,9.27,0.158,0,0,0.2,1.2
ENSMUSG00000035198,TUBG1,"tubulin, gamma 1",pericentriolar material|condensed nuclear chromosome|spindle pole|gamma-tubulin complex|cytoplasm|cytoplasm|centrosome|centrosome|centriole|microtubule organizing center|polar microtubule|cytoskeleton|microtubule|spindle microtubule|cytoplasmic microtubule|cilium|cell leading edge|nonmotile primary cilium|ciliary basal body|protein complex|apical part of cell|,GTP catabolic process|microtubule-based process|microtubule nucleation|mitotic spindle organization|regulation of mitosis|cytoplasmic microtubule organization|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|protein binding|GTP binding|,7,0.7,5.98,8,0.5,3.8,0.7,9.26,9.26,0.158,0,0,0.3,1.5
ENSMUSG00000024943,SMC5,structural maintenance of chromosomes 5,"chromosome, telomeric region|nucleus|nucleus|chromosome|PML body|cell junction|Smc5-Smc6 complex|",telomere maintenance via recombination|double-strand break repair via homologous recombination|DNA repair|DNA recombination|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|positive regulation of maintenance of mitotic sister chromatid cohesion|positive regulation of mitotic metaphase/anaphase transition|cell division|cellular senescence|,nucleotide binding|molecular_function|ATP binding|,10,0.4,6.28,10,0.3,3.64,0.3,9.24,9.24,0.158,0,0,0.1,0.9
ENSMUSG00000071650,GANAB,alpha glucosidase 2 alpha neutral subunit,endoplasmic reticulum|Golgi apparatus|membrane|glucosidase II complex|extracellular vesicular exosome|,carbohydrate metabolic process|N-glycan processing|metabolic process|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|protein binding|glucosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|glucan 1,3-alpha-glucosidase activity|poly(A) RNA binding|",10,0.4,5.82,10,0.4,3.71,0.4,9.17,9.17,0.159,0,0,0.1,0.9
ENSMUSG00000029687,EZH2,enhancer of zeste homolog 2 (Drosophila),nuclear chromatin|nuclear chromatin|nucleus|nucleus|chromosome|cytoplasm|ESC/E(Z) complex|ESC/E(Z) complex|pronucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|regulation of protein phosphorylation|DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of gene expression|negative regulation of gene expression|positive regulation of epithelial to mesenchymal transition|regulation of gliogenesis|skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration|chromatin modification|histone methylation|cerebellar cortex development|methylation|positive regulation of Ras GTPase activity|negative regulation of transcription elongation from RNA polymerase II promoter|regulation of cell proliferation|positive regulation of MAP kinase activity|negative regulation of epidermal cell differentiation|negative regulation of gene expression, epigenetic|negative regulation of transcription, DNA-templated|negative regulation of retinoic acid receptor signaling pathway|regulation of neurogenesis|negative regulation of striated muscle cell differentiation|cellular response to hydrogen peroxide|G1 to G0 transition|histone H3-K27 methylation|histone H3-K27 methylation|protein localization to chromatin|positive regulation of protein serine/threonine kinase activity|negative regulation of G1/S transition of mitotic cell cycle|",regulatory region DNA binding|core promoter binding|chromatin binding|chromatin binding|RNA binding|RNA binding|protein binding|methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|chromatin DNA binding|histone methyltransferase activity|histone methyltransferase activity|sequence-specific DNA binding|,10,-0.4,9.09,10,-0.2,1.39,-0.4,9.17,-9.17,0.159,0,0,-0.9,-0.1
ENSMUSG00000021965,SKA3,spindle and kinetochore associated complex subunit 3,"chromosome, centromeric region|kinetochore|condensed chromosome outer kinetochore|chromosome|cytoplasm|cytoskeleton|microtubule|spindle microtubule|",cell cycle|chromosome segregation|mitotic nuclear division|regulation of microtubule polymerization or depolymerization|cell division|,molecular_function|,10,0.6,1.39,10,0.5,8.3,0.5,9.14,9.14,0.16,0,0,0.2,1.2
ENSMUSG00000027878,NOTCH2,notch 2,cell|nucleus|nucleus|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cilium|cell surface|membrane|membrane|integral component of membrane|receptor complex|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|cell fate determination|cell fate determination|placenta development|heart looping|morphogenesis of an epithelial sheet|inflammatory response to antigenic stimulus|pulmonary valve morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|humoral immune response|cell cycle arrest|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|determination of left/right symmetry|positive regulation of cell proliferation|negative regulation of cell proliferation|organ morphogenesis|cell growth|cell differentiation|embryonic limb morphogenesis|positive regulation of BMP signaling pathway|wound healing|defense response to bacterium|myeloid dendritic cell differentiation|positive regulation of apoptotic process|positive regulation of osteoclast differentiation|positive regulation of Ras protein signal transduction|bone remodeling|regulation of developmental process|atrial septum morphogenesis|placenta blood vessel development|ciliary body morphogenesis|left/right axis specification|interleukin-4 secretion|",calcium ion binding|protein binding|enzyme binding|NF-kappaB binding|,10,-0.4,5.7,10,-0.3,3.69,-0.3,9,-9,0.163,0,0,-0.7,-0.1
ENSMUSG00000051413,PLAGL2,pleiomorphic adenoma gene-like 2,nucleus|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|lipid metabolic process|post-embryonic development|chylomicron assembly|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of intrinsic apoptotic signaling pathway|,sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|sequence-specific DNA binding|metal ion binding|,10,0.6,5.22,10,0.4,4.87,0.5,8.98,8.98,0.163,0,0,0.2,1.1
ENSMUSG00000010057,NPRL2,nitrogen permease regulator-like 2,None,protein phosphorylation|negative regulation of kinase activity|,protein kinase activity|GTPase activator activity|,10,0.5,6.15,10,0.4,3.34,0.4,8.93,8.93,0.164,0,0,0.1,1.1
ENSMUSG00000026605,CENPF,centromere protein F,"chromosome, centromeric region|spindle pole|condensed chromosome outer kinetochore|nucleus|nucleus|nucleus|nuclear envelope|cytoplasm|spindle|nuclear matrix|midbody|pronucleus|","mitotic G2 phase|mitotic M phase|mitotic cell cycle|chromosome segregation|regulation of G2/M transition of mitotic cell cycle|protein transport|regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|metaphase plate congression|",protein C-terminus binding|transcription factor binding|protein homodimerization activity|dynein binding|,10,0.6,10.5,10,0.1,0.00894,0.5,8.79,8.79,0.167,0,0,0.2,1.3
ENSMUSG00000027509,RAE1,RAE1 RNA export 1 homolog (S. pombe),nucleus|nucleolus|cytoplasm|,cellular response to organic cyclic compound|,None,10,1.1,10.2,10,0.4,2.36,1.1,8.68,8.68,0.169,0,0,0.4,1.9
ENSMUSG00000029599,DDX54,DEAD (Asp-Glu-Ala-Asp) box polypeptide 54,nucleus|nucleolus|membrane|,"ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|RNA processing|RNA metabolic process|regulation of RNA biosynthetic process|","nucleotide binding|nucleic acid binding|transcription corepressor activity|RNA binding|ATP-dependent RNA helicase activity|helicase activity|receptor binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|estrogen receptor binding|poly(A) RNA binding|",10,0.8,4.94,10,0.9,4.17,0.8,8.68,8.68,0.169,0,0,0.3,1.6
ENSMUSG00000031229,ATRX,alpha thalassemia/mental retardation syndrome X-linked homolog (human),"nuclear chromosome|chromosome, telomeric region|heterochromatin|intracellular|nucleus|nucleus|chromosome|nucleolus|cytoplasm|mitochondrion|telomeric heterochromatin|SWI/SNF superfamily-type complex|","ATP catabolic process|DNA repair|nucleosome assembly|DNA replication-independent nucleosome assembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|spermatogenesis|positive regulation of nuclear cell cycle DNA replication|chromatin modification|DNA damage response, signal transduction by p53 class mediator|forebrain development|replication fork processing|positive regulation of telomere maintenance|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|Sertoli cell development|seminiferous tubule development|cellular response to hydroxyurea|negative regulation of telomeric RNA transcription from RNA pol II promoter|",nucleotide binding|DNA binding|chromatin binding|helicase activity|protein binding|ATP binding|zinc ion binding|DNA translocase activity|hydrolase activity|methylated histone binding|histone binding|histone binding|metal ion binding|chromo shadow domain binding|,10,-0.8,9.7,10,-0.2,1.03,-0.5,8.53,-8.53,0.172,0,0,-1.6,-0.2
ENSMUSG00000009013,DYNLL1,dynein light chain LC8-type 1,kinetochore|nucleus|cytoplasm|mitochondrion|centrosome|cytosol|cytoskeleton|cytoplasmic dynein complex|cytoplasmic dynein complex|microtubule|microtubule associated complex|COP9 signalosome|membrane|membrane|dynein complex|extracellular vesicular exosome|mitotic spindle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|apoptotic process|microtubule-based process|microtubule-based movement|negative regulation of phosphorylation|negative regulation of catalytic activity|negative regulation of nitric oxide biosynthetic process|regulation of catalytic activity|",motor activity|enzyme inhibitor activity|protein binding|protein C-terminus binding|enzyme binding|protein domain specific binding|nitric-oxide synthase regulator activity|protein homodimerization activity|,10,-0.2,1.73,10,-0.5,8.54,-0.5,8.46,-8.46,0.173,0,0,-1.1,-0.1
ENSMUSG00000031954,CFDP1,craniofacial development protein 1,basement membrane|,cell adhesion|multicellular organismal development|regulation of cell shape|regulation of cell proliferation|negative regulation of fibroblast apoptotic process|,None,10,0.8,3.07,10,0.8,5.71,0.8,8.44,8.44,0.174,0,0,0.4,1.7
ENSMUSG00000036144,MEOX2,mesenchyme homeobox 2,nucleus|cytoplasm|,"angiogenesis|somite specification|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|skeletal muscle tissue development|positive regulation of transcription from RNA polymerase II promoter|palate development|limb development|neuron death|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|,10,0,0,10,0.7,10.8,0.7,8.38,8.38,0.175,0,0,0.2,1.4
ENSMUSG00000057836,XLR3A,X-linked lymphocyte-regulated 3A,cellular_component|,biological_process|,molecular_function|,3,-1,7.27,3,-0.4,2.74,-1,8.35,-8.35,0.175,0,0,-2,1.8
ENSMUSG00000052056,ZFP217,zinc finger protein 217,histone deacetylase complex|nucleoplasm|,"regulation of transcription, DNA-templated|cell aging|negative regulation of transcription, DNA-templated|",transcription regulatory region DNA binding|,10,0.1,0.454,10,0.5,9.19,0.4,8.29,8.29,0.177,0,0,0.1,1
ENSMUSG00000060073,PSMA3,"proteasome (prosome, macropain) subunit, alpha type 3","proteasome complex|nucleus|cytoplasm|proteasome core complex|proteasome core complex|proteasome core complex, alpha-subunit complex|extracellular vesicular exosome|",proteolysis|ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|protein binding|peptidase activity|hydrolase activity|,6,1.1,8.62,7,-0.9,1.52,0.9,8.28,8.28,0.177,0,0,-1.3,2
ENSMUSG00000032350,GCLC,"glutamate-cysteine ligase, catalytic subunit",cytosol|glutamate-cysteine ligase complex|glutamate-cysteine ligase complex|,"cysteine metabolic process|glutamate metabolic process|glutathione metabolic process|glutathione biosynthetic process|glutathione biosynthetic process|glutathione biosynthetic process|response to oxidative stress|apoptotic mitochondrial changes|response to heat|response to xenobiotic stimulus|response to hormone|L-ascorbic acid metabolic process|negative regulation of protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|cell redox homeostasis|negative regulation of transcription, DNA-templated|response to arsenic-containing substance|regulation of blood vessel size|response to nitrosative stress|regulation of mitochondrial depolarization|negative regulation of extrinsic apoptotic signaling pathway|",nucleotide binding|magnesium ion binding|glutamate-cysteine ligase activity|glutamate-cysteine ligase activity|glutamate-cysteine ligase activity|ATP binding|glutamate binding|ligase activity|ADP binding|protein heterodimerization activity|protein heterodimerization activity|coenzyme binding|,10,1.4,5.97,10,0.6,4.76,0.6,8.21,8.21,0.178,0,0,0.2,2.2
ENSMUSG00000043858,NUP62,nucleoporin 62,nucleus|nuclear envelope|nuclear pore|nuclear pore|cytoplasm|cytoskeleton|ribonucleoprotein complex|nuclear membrane|nuclear membrane|intracellular membrane-bounded organelle|,"transcription, DNA-templated|transport|cell surface receptor signaling pathway|cell aging|cell death|negative regulation of cell proliferation|negative regulation of cell proliferation|protein transport|cell migration|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of apoptotic process|negative regulation of programmed cell death|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of MAP kinase activity|positive regulation of transcription, DNA-templated|negative regulation of Ras protein signal transduction|mRNA transport|",protein binding|structural constituent of nuclear pore|receptor signaling complex scaffold activity|SH2 domain binding|ubiquitin binding|thyroid hormone receptor binding|PTB domain binding|,10,-0.1,0.655,10,-0.8,10.1,-0.8,8.2,-8.2,0.178,0,0,-1.7,-0.2
ENSMUSG00000062352,ITGB1BP1,integrin beta 1 binding protein 1,ruffle|ruffle|nucleus|cytoplasm|cytosol|cytoskeleton|plasma membrane|membrane|lamellipodium|lamellipodium|cell projection|perinuclear region of cytoplasm|extracellular vesicular exosome|cell periphery|,"angiogenesis|blood vessel endothelial cell proliferation involved in sprouting angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of protein kinase activity|negative regulation of cell adhesion involved in substrate-bound cell migration|cell adhesion|cell-matrix adhesion|Notch signaling pathway|integrin-mediated signaling pathway|positive regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of endothelial cell migration|negative regulation of fibroblast migration|protein transport|cell differentiation|regulation of cell adhesion|biomineral tissue development|negative regulation of protein binding|activation of protein kinase B activity|integrin activation|regulation of cell adhesion mediated by integrin|tube formation|cellular response to vascular endothelial growth factor stimulus|regulation of Cdc42 GTPase activity|receptor clustering|cellular response to fibroblast growth factor stimulus|positive regulation of Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|regulation of blood vessel size|myoblast migration|positive regulation of stress fiber assembly|positive regulation of cell division|positive regulation of focal adhesion assembly|negative regulation of focal adhesion assembly|negative regulation of focal adhesion assembly|positive regulation of protein kinase B signaling|negative regulation of ERK1 and ERK2 cascade|negative regulation of cell migration involved in sprouting angiogenesis|positive regulation of protein targeting to membrane|negative regulation of protein targeting to membrane|negative regulation of substrate adhesion-dependent cell spreading|negative regulation of substrate adhesion-dependent cell spreading|regulation of integrin-mediated signaling pathway|regulation of integrin-mediated signaling pathway|",GDP-dissociation inhibitor activity|integrin binding|protein binding|protein C-terminus binding|protein transporter activity|kinase binding|protein kinase binding|protein complex binding|,10,0.7,4.57,10,0.3,4.9,0.6,8.19,8.19,0.179,0,0,0.1,1.2
ENSMUSG00000039488,CNTN5,contactin 5,cytoplasm|plasma membrane|membrane|anchored component of membrane|,cell adhesion|sensory perception of sound|,None,10,-0.7,5.02,10,-0.4,4.54,-0.5,8.15,-8.15,0.179,0,0,-1.2,-0.1
ENSMUSG00000033417,CACUL1,"CDK2 associated, cullin domain 1",cellular_component|cullin-RING ubiquitin ligase complex|,G1/S transition of mitotic cell cycle|ubiquitin-dependent protein catabolic process|cell cycle|positive regulation of cell proliferation|positive regulation of protein kinase activity|,protein kinase binding|ubiquitin protein ligase binding|,10,0.4,3.43,10,0.3,5.1,0.4,8.12,8.12,0.18,0,0,0.1,0.9
ENSMUSG00000026743,MLLT10,"myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10",nucleus|cytoplasm|,positive regulation of transcription from RNA polymerase II promoter|,zinc ion binding|metal ion binding|,10,0,0,10,-1.5,11.4,-1.5,8.06,-8.06,0.181,0,0,-3,-0.2
ENSMUSG00000030403,VASP,vasodilator-stimulated phosphoprotein,cytoplasm|cytoskeleton|plasma membrane|tight junction|focal adhesion|focal adhesion|membrane|lamellipodium|cell junction|filopodium|cell projection|extracellular vesicular exosome|,neural tube closure|axon guidance|actin polymerization or depolymerization|actin cytoskeleton organization|positive regulation of actin filament polymerization|protein homotetramerization|,actin binding|protein binding|profilin binding|SH3 domain binding|,10,-0.3,4.57,10,-0.3,3.81,-0.3,8.04,-8.04,0.182,0,0,-0.7,-0.1
ENSMUSG00000039193,NLRC4,"NLR family, CARD domain containing 4",cell|cytoplasm|cytosol|IPAF inflammasome complex|,activation of innate immune response|immune system process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|inflammatory response|detection of bacterium|detection of bacterium|defense response to bacterium|defense response to bacterium|regulation of apoptotic process|positive regulation of apoptotic process|regulation of cysteine-type endopeptidase activity involved in apoptotic process|innate immune response|interleukin-1 beta secretion|interleukin-1 beta secretion|positive regulation of NF-kappaB transcription factor activity|protein homooligomerization|pyroptosis|,nucleotide binding|ATP binding|identical protein binding|protein homodimerization activity|,10,-1,11.2,10,0.2,0.0705,-1,8.02,-8.02,0.182,0,0,-2,1.6
ENSMUSG00000023224,SERPING1,"serine (or cysteine) peptidase inhibitor, clade G, member 1",extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|blood microparticle|,"negative regulation of complement activation, lectin pathway|immune system process|complement activation, classical pathway|blood coagulation|hemostasis|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|regulation of blood coagulation|fibrinolysis|innate immune response|negative regulation of complement activation|",complement binding|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.9,5.63,10,-1.2,11.3,-1.1,7.98,-7.98,0.183,0,0,-2,0.8
ENSMUSG00000037343,TAF2,"TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|transcription factor TFIID complex|transcription factor TFTC complex|,"G2/M transition of mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",metallopeptidase activity|zinc ion binding|transcription regulatory region DNA binding|,9,0.4,7.94,9,-0.7,4.18,-0.8,7.97,-7.97,0.183,0,0,-2,1.3
ENSMUSG00000095264,GM2854,predicted gene 2854,None,None,None,3,0.9,8.9,3,0.3,0.163,0.8,7.97,7.97,0.183,0,0,0.4,2
ENSMUSG00000058729,LIN9,lin-9 homolog (C. elegans),nucleus|transcriptional repressor complex|,"DNA replication|transcription, DNA-templated|cell cycle|",None,9,0.4,7.72,10,0.3,0.485,0.4,7.93,7.93,0.184,0,0,0.1,1
ENSMUSG00000028426,RAD23B,RAD23b homolog (S. cerevisiae),proteasome complex|nucleus|cytoplasm|XPC complex|,"nucleotide-excision repair, DNA damage recognition|DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|spermatogenesis|regulation of proteasomal ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|",damaged DNA binding|protein binding|polyubiquitin binding|,10,0.8,9.87,10,0.1,0.0756,0.8,7.87,7.87,0.186,0,0,0.2,1.7
ENSMUSG00000030726,POLD3,"polymerase (DNA-directed), delta 3, accessory subunit",nucleus|mitochondrion|,"DNA replication|DNA-dependent DNA replication|nucleotide-excision repair, DNA gap filling|",DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|,9,-0.5,4.39,9,1.1,7.11,0.7,7.86,7.86,0.186,0,0,-0.4,2
ENSMUSG00000030047,ARHGAP25,Rho GTPase activating protein 25,intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,-0.5,2.82,10,-0.5,5.38,-0.5,7.86,-7.86,0.186,0,0,-1,-0.1
ENSMUSG00000071646,MTA2,"metastasis-associated gene family, member 2",histone deacetylase complex|nuclear chromatin|nucleus|nucleus|transcription factor complex|membrane|NuRD complex|NuRD complex|NuRD complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|DNA methylation|DNA packaging|chromatin remodeling|regulation of transcription, DNA-templated|histone deacetylation|ATP-dependent chromatin remodeling|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|transcription factor binding transcription factor activity|RNA polymerase II transcription factor binding|RNA polymerase II repressing transcription factor binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|histone deacetylase activity|protein binding|zinc ion binding|nucleosomal DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0.8,3.28,10,0.9,4.88,0.8,7.79,7.79,0.187,0,0,0.2,1.8
ENSMUSG00000045996,POLR2K,polymerase (RNA) II (DNA directed) polypeptide K,"nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase I complex|","transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",RNA polymerase I activity|RNA polymerase II activity|RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|metal ion binding|,9,-0.2,0.593,9,0.9,9.91,0.9,7.77,7.77,0.188,0,0,0.4,1.9
ENSMUSG00000024989,CEP55,centrosomal protein 55,cytoplasm|centrosome|cytoskeleton|membrane|midbody|midbody|intercellular bridge|,mitotic cytokinesis|cell cycle|mitotic nuclear division|establishment of protein localization|cell division|,protein binding|,10,0.7,10.3,10,-0.6,7.83,0.6,7.76,7.76,0.188,0,0,-0.7,2
ENSMUSG00000047757,FANCB,"Fanconi anemia, complementation group B",nucleus|Fanconi anaemia nuclear complex|,DNA repair|cellular response to DNA damage stimulus|biological_process|,molecular_function|,10,0.9,10.1,10,-0.8,1.69,0.8,7.75,7.75,0.188,0,0,-1.2,2
ENSMUSG00000026361,CDC73,"cell division cycle 73, Paf1/RNA polymerase II complex component",nucleus|Cdc73/Paf1 complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|endodermal cell fate commitment|transcription, DNA-templated|mRNA polyadenylation|cell cycle|negative regulation of cell proliferation|histone monoubiquitination|Wnt signaling pathway|stem cell maintenance|positive regulation of Wnt signaling pathway|positive regulation of mRNA 3'-end processing|protein destabilization|positive regulation of transcription elongation from RNA polymerase II promoter|histone H2B ubiquitination|negative regulation of myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|negative regulation of fibroblast proliferation|negative regulation of epithelial cell proliferation|cellular response to lipopolysaccharide|negative regulation of G1/S transition of mitotic cell cycle|",RNA polymerase II core binding|protein binding|,8,1.3,5.06,8,-0.6,6.23,-0.5,7.71,-7.71,0.189,0,0,-1.6,1.6
ENSMUSG00000050310,RICTOR,"RPTOR independent companion of MTOR, complex 2",TORC2 complex|TORC2 complex|,positive regulation of endothelial cell proliferation|multicellular organismal development|embryo development|positive regulation of actin filament polymerization|actin cytoskeleton reorganization|TOR signaling|positive regulation of TOR signaling|regulation of Rac GTPase activity|regulation of actin cytoskeleton organization|regulation of phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|regulation of protein kinase B signaling|regulation of protein kinase B signaling|positive regulation of protein kinase B signaling|,protein binding|ribosome binding|,10,0.4,6.52,10,0.8,2.09,0.5,7.7,7.7,0.19,0,0,0.1,1.1
ENSMUSG00000007613,TGFBR1,"transforming growth factor, beta receptor I",endosome|plasma membrane|caveola|tight junction|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|cell junction|protein complex|receptor complex|membrane raft|,"activation of MAPKK activity|skeletal system development|angiogenesis|in utero embryonic development|kidney development|blastocyst development|epithelial to mesenchymal transition|negative regulation of endothelial cell proliferation|lens development in camera-type eye|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|apoptotic process|signal transduction|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|heart development|positive regulation of cell proliferation|germ cell migration|embryo development|post-embryonic development|anterior/posterior pattern specification|regulation of gene expression|positive regulation of pathway-restricted SMAD protein phosphorylation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|cell differentiation|collagen fibril organization|positive regulation of cell growth|regulation of protein ubiquitination|negative regulation of chondrocyte differentiation|regulation of growth|negative regulation of apoptotic process|regulation of protein binding|endothelial cell migration|response to estrogen|negative regulation of endothelial cell differentiation|positive regulation of transcription, DNA-templated|protein autophosphorylation|thymus development|neuron fate commitment|embryonic cranial skeleton morphogenesis|skeletal system morphogenesis|artery morphogenesis|cell motility|positive regulation of cellular component movement|positive regulation of filopodium assembly|positive regulation of protein kinase B signaling|parathyroid gland development|palate development|palate development|pharyngeal system development|pathway-restricted SMAD protein phosphorylation|positive regulation of SMAD protein import into nucleus|response to cholesterol|response to cholesterol|cellular response to transforming growth factor beta stimulus|cellular response to transforming growth factor beta stimulus|positive regulation of apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta receptor activity, type I|type II transforming growth factor beta receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|ubiquitin protein ligase binding|protein complex binding|SMAD binding|SMAD binding|metal ion binding|protein heterodimerization activity|transforming growth factor beta binding|transforming growth factor beta binding|transforming growth factor beta binding|I-SMAD binding|",10,-0.5,2.6,10,-0.4,5.35,-0.4,7.59,-7.59,0.192,0,0,-1,-0.1
ENSMUSG00000024795,KIF20B,kinesin family member 20B,nucleus|nucleoplasm|cytoplasm|centrosome|cytoskeleton|microtubule|,neural tube closure|ATP catabolic process|microtubule-based movement|cell cycle|mitotic nuclear division|regulation of mitosis|cell division|regulation of establishment of protein localization|regulation of establishment of cell polarity|regulation of neuron migration|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|ATPase activity|WW domain binding|,10,-0.1,0.0114,10,-1.1,10.4,-1,7.48,-7.48,0.195,0,0,-1.9,-0.2
ENSMUSG00000038774,ASCC3,activating signal cointegrator 1 complex subunit 3,intracellular|nucleus|cytoplasm|Golgi apparatus|membrane|,"ATP catabolic process|DNA repair|DNA dealkylation involved in DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell proliferation|DNA duplex unwinding|",nucleotide binding|nucleic acid binding|helicase activity|ATP binding|hydrolase activity|ATP-dependent 3'-5' DNA helicase activity|poly(A) RNA binding|,10,0.6,6.93,10,0.3,1.46,0.5,7.43,7.43,0.196,0,0,0.1,1.2
ENSMUSG00000018286,PSMB6,"proteasome (prosome, macropain) subunit, beta type 6",proteasome complex|nucleus|cytoplasm|proteasome core complex|extracellular vesicular exosome|,proteolysis|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,8,0.6,5.22,8,0.4,2.74,0.6,7.39,7.39,0.197,0,0,0.1,1.4
ENSMUSG00000020329,POLRMT,polymerase (RNA) mitochondrial (DNA directed),mitochondrion|mitochondrion|mitochondrial nucleoid|,"transcription, DNA-templated|transcription from mitochondrial promoter|",DNA binding|DNA-directed RNA polymerase activity|transferase activity|nucleotidyltransferase activity|poly(A) RNA binding|,10,0.7,10,10,0,0,0.6,7.37,7.37,0.197,0,0,0.2,1.6
ENSMUSG00000026134,PRIM2,"DNA primase, p58 subunit",primosome complex|,"DNA replication|DNA replication, synthesis of RNA primer|transcription, DNA-templated|","DNA binding|telomerase activity|RNA helicase activity|DNA primase activity|DNA-directed RNA polymerase activity|sulfate adenylyltransferase activity|RNA guanylyltransferase activity|tRNA guanylyltransferase activity|mannose-phosphate guanylyltransferase activity|transferase activity|nucleotidyltransferase activity|DNA/RNA helicase activity|CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity|phospholactate guanylyltransferase activity|ATP:coenzyme F420 adenylyltransferase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|UDP-N-acetylgalactosamine diphosphorylase activity|",10,0.5,6.52,10,0.3,1.77,0.5,7.31,7.31,0.199,0,0,0.1,1.2
ENSMUSG00000031862,ATP13A1,ATPase type 13A1,endoplasmic reticulum|membrane|membrane|integral component of membrane|,transport|cation transport|,nucleotide binding|molecular_function|ATP binding|hydrolase activity|ATPase activity|cation-transporting ATPase activity|metal ion binding|,10,0.4,3.98,10,0.5,3.7,0.4,7.24,7.24,0.2,0,0,0.1,1.1
ENSMUSG00000026281,DTYMK,deoxythymidylate kinase,mitochondrion|mitochondrial intermembrane space|mitochondrial matrix|,dTDP biosynthetic process|dTDP biosynthetic process|dTTP biosynthetic process|nucleotide biosynthetic process|phosphorylation|nucleotide phosphorylation|nucleotide phosphorylation|nucleoside monophosphate phosphorylation|cellular response to growth factor stimulus|,nucleotide binding|thymidylate kinase activity|thymidylate kinase activity|ATP binding|kinase activity|transferase activity|nucleoside phosphate kinase activity|,7,-0.1,0.102,7,1.1,9.38,1,7.2,7.2,0.201,0,0,0.2,2
ENSMUSG00000040548,TEX2,testis expressed gene 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.1,4.72,10,1,2.9,1,7.19,7.19,0.202,0,0,0.5,2
ENSMUSG00000060509,XCR1,chemokine (C motif) receptor 1,intracellular|cell|plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|response to cytokine|release of sequestered calcium ion into cytosol|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|,10,0.7,10.1,10,-0.3,2.44,0.7,7.18,7.18,0.202,0,0,-0.4,2
ENSMUSG00000016541,ATXN10,ataxin 10,extracellular space|cytoplasm|cytosol|plasma membrane|membrane|dendrite|neuronal cell body|perinuclear region of cytoplasm|,nervous system development|neuron projection development|,protein binding|identical protein binding|,10,0.2,1.32,10,0.8,8.52,0.5,7.14,7.14,0.203,0,0,0.2,1.5
ENSMUSG00000019210,ATP6V1E1,"ATPase, H+ transporting, lysosomal V1 subunit E1","cytoplasm|mitochondrion|lysosomal membrane|endosome|cytosol|microvillus|apical plasma membrane|proton-transporting two-sector ATPase complex, catalytic domain|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|,"protein binding|hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrolase activity|proton-transporting ATPase activity, rotational mechanism|ATPase binding|",9,1,5.07,9,0.4,3.88,0.7,7.07,7.07,0.205,0,0,0.2,1.7
ENSMUSG00000022945,CHAF1B,"chromatin assembly factor 1, subunit B (p60)",nuclear chromatin|nucleus|nucleoplasm|cytosol|CAF-1 complex|protein complex|,"DNA replication|DNA repair|DNA replication-dependent nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle|chromatin assembly|",protein binding|,9,0.2,1.18,9,0.9,8.53,0.9,7.03,7.03,0.206,0,0,0.2,1.7
ENSMUSG00000031818,COX4I1,cytochrome c oxidase subunit IV isoform 1,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|membrane|extracellular vesicular exosome|,None,cytochrome-c oxidase activity|,10,0.2,1.85,10,1,6.81,0.6,7.01,7.01,0.206,0,0,0.1,1.7
ENSMUSG00000004530,CORO1C,"coronin, actin binding protein 1C",cytoplasm|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|cell projection|,actin cortical patch assembly|phagocytosis|actin cytoskeleton organization|actin cytoskeleton organization|,actin binding|actin filament binding|,10,0.4,4.6,10,0.5,2.79,0.5,7.01,7.01,0.206,0,0,0.1,1.3
ENSMUSG00000035401,2210018M11RIK,RIKEN cDNA 2210018M11 gene,nucleus|,"DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|chromatin modification|",protein binding|protein homodimerization activity|,9,-0.1,0.405,9,0.7,9.03,0.6,7,7,0.207,0,0,0.1,1.8
ENSMUSG00000004872,PAX3,paired box 3,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|neural crest cell migration|neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|heart development|muscle organ development|cell proliferation|positive regulation of cell proliferation|regulation of somitogenesis|regulation of somitogenesis|cell migration|spinal cord association neuron differentiation|neural tube development|skeletal muscle cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|developmental pigmentation|neuron fate commitment|cardiac muscle cell differentiation|mammary gland specification|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|sequence-specific DNA binding|HMG box domain binding|,10,-0.5,4.27,10,-0.5,3.05,-0.5,6.99,-6.99,0.207,0,0,-1.2,-0.1
ENSMUSG00000063229,LDHA,lactate dehydrogenase A,nucleus|cytoplasm|mitochondrion|cytosol|membrane|sperm fibrous sheath|extracellular vesicular exosome|,carbohydrate metabolic process|glycolytic process|lactate biosynthetic process from pyruvate|cellular response to extracellular stimulus|cellular carbohydrate metabolic process|oxidation-reduction process|,"catalytic activity|L-lactate dehydrogenase activity|L-lactate dehydrogenase activity|protein binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|",10,0,0,10,0.6,9.29,0.6,6.91,6.91,0.21,0,0,0.1,1.6
ENSMUSG00000007815,RHOA,"ras homolog gene family, member A",intracellular|nucleus|cytoplasm|mitochondrion|cytosol|cytosol|cytosol|cytoskeleton|plasma membrane|cell cortex|membrane|lamellipodium|axon|ruffle membrane|cell projection|apical junction complex|extracellular vesicular exosome|,cell morphogenesis|GTP catabolic process|GTP catabolic process|regulation of transcription from RNA polymerase II promoter|cytoskeleton organization|cell cycle|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|small GTPase mediated signal transduction|Rho protein signal transduction|skeletal muscle tissue development|cerebral cortex cell migration|forebrain radial glial cell differentiation|actin cytoskeleton organization|cell differentiation|positive regulation of cell growth|regulation of cell migration|androgen receptor signaling pathway|positive regulation of actin filament polymerization|stress-activated protein kinase signaling cascade|positive regulation of cytokinesis|negative regulation of intracellular steroid hormone receptor signaling pathway|regulation of osteoblast proliferation|cleavage furrow formation|response to drug|negative regulation of I-kappaB kinase/NF-kappaB signaling|stress fiber assembly|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|apical junction assembly|apical junction assembly|negative regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|ossification involved in bone maturation|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of smooth muscle contraction|regulation of dendrite development|cell division|positive regulation of stress fiber assembly|regulation of calcium ion transport|negative regulation of cell death|trabecula morphogenesis|positive regulation of podosome assembly|spindle assembly involved in mitosis|regulation of neural precursor cell proliferation|,nucleotide binding|GTPase activity|GTPase activity|GTPase activity|protein binding|GTP binding|myosin binding|GDP binding|protein domain specific binding|,10,1.1,5.18,10,0.4,4.24,0.8,6.87,6.87,0.211,0,0,0.1,1.8
ENSMUSG00000039842,MCPH1,"microcephaly, primary autosomal recessive 1",cell|cytoplasm|cytoskeleton|,establishment of mitotic spindle orientation|regulation of gene expression|regulation of gene expression|cerebral cortex development|regulation of kinase activity|regulation of centrosome cycle|regulation of inflammatory response|bone development|regulation of chromosome condensation|protein localization to centrosome|neuronal stem cell maintenance|,identical protein binding|,10,0.6,1.88,10,0.5,5.39,0.5,6.8,6.8,0.213,0,0,-0.2,1.5
ENSMUSG00000000028,CDC45,cell division cycle 45,nucleus|centrosome|,DNA replication|DNA replication initiation|cell cycle|cell division|,None,10,0.6,4.1,10,-1.3,9.28,-1.3,6.72,-6.72,0.216,0,0,-3,-0.1
ENSMUSG00000042043,TBCA,tubulin cofactor A,nucleolus|cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|extracellular vesicular exosome|,tubulin complex assembly|,poly(A) RNA binding|unfolded protein binding|,8,-0.1,0.0852,8,0.9,9.02,0.9,6.71,6.71,0.216,0,0,0.3,1.9
ENSMUSG00000006498,PTBP1,polypyrimidine tract binding protein 1,nucleus|membrane|extracellular vesicular exosome|,"regulation of alternative mRNA splicing, via spliceosome|mRNA processing|RNA splicing|negative regulation of RNA splicing|negative regulation of mRNA splicing, via spliceosome|negative regulation of muscle cell differentiation|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|pre-mRNA binding|poly(A) RNA binding|,10,1.3,5.84,10,0.6,2.45,1,6.69,6.69,0.217,0,0,0.4,2
ENSMUSG00000001924,UBA1,ubiquitin-like modifier activating enzyme 1,heterochromatin|nucleus|nucleus|cytoplasm|mitochondrion|lysosomal membrane|cytosol|endosome membrane|desmosome|rough endoplasmic reticulum membrane|extracellular vesicular exosome|,cellular protein modification process|cellular response to DNA damage stimulus|protein ubiquitination|modification-dependent protein catabolic process|,nucleotide binding|catalytic activity|ubiquitin activating enzyme activity|ubiquitin-protein transferase activity|protein binding|ATP binding|small protein activating enzyme activity|ligase activity|poly(A) RNA binding|,9,1.1,7.29,9,-0.6,3.43,0.9,6.63,6.63,0.218,0,0,-0.9,2
ENSMUSG00000028381,UGCG,UDP-glucose ceramide glucosyltransferase,Golgi apparatus|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|,"ceramide glucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.2,1.25,10,-0.9,8.45,-0.9,6.62,-6.62,0.219,0,0,-1.9,-0.1
ENSMUSG00000031209,HEPH,hephaestin,intracellular|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|perinuclear region of cytoplasm|,transport|ion transport|copper ion transport|iron ion transport|iron ion transport|cellular iron ion homeostasis|erythrocyte differentiation|iron ion homeostasis|oxidation-reduction process|,ferroxidase activity|copper ion binding|ferrous iron binding|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|epoxyqueuosine reductase activity|,10,0.5,2.33,10,0.5,4.59,0.5,6.61,6.61,0.219,0,0,0.1,1.4
ENSMUSG00000028636,PPCS,phosphopantothenoylcysteine synthetase,extracellular vesicular exosome|,coenzyme A biosynthetic process|,phosphopantothenate--cysteine ligase activity|ligase activity|,8,0,0,8,0.4,8.58,0.4,6.57,6.57,0.22,0,0,-0.1,1.2
ENSMUSG00000042590,IPO11,importin 11,intracellular|cell|nucleus|cytoplasm|,ribosomal protein import into nucleus|transport|intracellular protein transport|protein transport|,protein binding|Ran GTPase binding|protein transporter activity|,10,1.8,7.89,10,0.3,2.49,0.4,6.55,6.55,0.22,0,0,0.2,2.7
ENSMUSG00000049739,ZFP646,zinc finger protein 646,cellular_component|,biological_process|,molecular_function|,10,0.6,8.2,10,-0.2,0.651,0.5,6.5,6.5,0.222,0,0,0,1.5
ENSMUSG00000071076,JUND,jun D proto-oncogene,nucleus|protein complex|,"osteoblast development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of osteoblast differentiation|positive regulation of transcription from RNA polymerase II promoter|cellular response to calcium ion|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|ligand-dependent nuclear receptor binding|enzyme binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,-0.3,1.74,10,-0.3,5.03,-0.3,6.47,-6.47,0.223,0,0,-0.8,0
ENSMUSG00000000171,SDHD,"succinate dehydrogenase complex, subunit D, integral membrane protein",mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial inner membrane|membrane|integral component of membrane|,tricarboxylic acid cycle|transport|regulation of catecholamine secretion|oxidation-reduction process|cellular response to hypoxia|,succinate dehydrogenase activity|succinate dehydrogenase activity|metal ion binding|,10,0.4,7.27,10,-0.8,7.35,0.4,6.45,6.45,0.224,0,0,-1.4,1.3
ENSMUSG00000004267,ENO2,"enolase 2, gamma neuronal",phosphopyruvate hydratase complex|photoreceptor inner segment|extracellular space|intracellular|cytoplasm|cytoplasm|plasma membrane|membrane|neuron projection|neuronal cell body|perikaryon|extracellular vesicular exosome|synaptic membrane|,glycolytic process|,magnesium ion binding|phosphopyruvate hydratase activity|lyase activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,0.5,6.27,10,0.2,1.06,0.4,6.4,6.4,0.225,0,0,0,1.3
ENSMUSG00000033933,VHL,von Hippel-Lindau tumor suppressor,nucleus|cytoplasm|mitochondrion|cytosol|cilium|membrane|VCB complex|intermediate filament cytoskeleton|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|response to hypoxia|regulation of transcription, DNA-templated|proteasomal protein catabolic process|protein ubiquitination|protein catabolic process|neuron differentiation|extracellular matrix organization|regulation of catecholamine metabolic process|blood vessel endothelial cell migration|positive regulation of transcription, DNA-templated|protein heterooligomerization|negative regulation of transcription from RNA polymerase II promoter in response to hypoxia|regulation of thymocyte apoptotic process|negative regulation of thymocyte apoptotic process|regulation of apoptotic signaling pathway|",protein binding|transcription factor binding|enzyme binding|protein complex binding|protein complex binding|,9,0.3,1.6,9,1.1,7.11,0.9,6.37,6.37,0.227,0,0,-0.3,2
ENSMUSG00000031271,SERPINA7,"serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7",extracellular region|extracellular space|extracellular vesicular exosome|,post-embryonic development|negative regulation of endopeptidase activity|regulation of proteolysis|response to vitamin A|response to drug|thyroid hormone transport|,serine-type endopeptidase inhibitor activity|hormone binding|,10,-1,2.36,10,-1,4.31,-1,6.36,-6.36,0.227,0,0,-2,-0.3
ENSMUSG00000029020,MFN2,mitofusin 2,mitochondrion|mitochondrion|mitochondrial outer membrane|cytosol|microtubule cytoskeleton|membrane|integral component of membrane|intrinsic component of mitochondrial outer membrane|,blastocyst formation|GTP catabolic process|protein targeting to mitochondrion|mitochondrial membrane organization|multicellular organismal development|mitochondrial fusion|mitochondrial fusion|protein localization to pre-autophagosomal structure|negative regulation of Ras protein signal transduction|camera-type eye morphogenesis|negative regulation of smooth muscle cell proliferation|mitochondrion localization|,nucleotide binding|GTPase activity|protein binding|GTP binding|hydrolase activity|ubiquitin protein ligase binding|GTPase binding|,9,0.2,0.707,9,0.6,7.09,0.5,6.34,6.34,0.228,0,0,0.1,1.4
ENSMUSG00000020515,CNOT8,"CCR4-NOT transcription complex, subunit 8",intracellular|nucleus|cytoplasm|CCR4-NOT complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|positive regulation of cell proliferation|gene silencing by RNA|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|nucleic acid binding|RNA binding|nuclease activity|exonuclease activity|poly(A)-specific ribonuclease activity|hydrolase activity|metal ion binding|,10,-0.4,3.65,10,-0.3,3.04,-0.3,6.33,-6.33,0.228,0,0,-0.9,0
ENSMUSG00000029209,GNPDA2,glucosamine-6-phosphate deaminase 2,nucleus|cytoplasm|,carbohydrate metabolic process|N-acetylglucosamine metabolic process|,glucosamine-6-phosphate deaminase activity|hydrolase activity|,10,1.2,7.89,10,0.4,0.874,0.9,6.28,6.28,0.23,0,0,0.2,2
ENSMUSG00000028693,NASP,nuclear autoantigenic sperm protein (histone-binding),nuclear chromatin|nucleus|nucleus|cytoplasm|protein complex|,blastocyst development|DNA replication|DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|transport|cell cycle|cell proliferation|protein transport|histone exchange|,protein binding|histone binding|Hsp90 protein binding|,10,1,7.81,10,-0.2,0.439,0.8,6.21,6.21,0.232,0,0,-0.8,2
ENSMUSG00000021624,CD180,CD180 antigen,plasma membrane|membrane|integral component of membrane|,B cell proliferation involved in immune response|immune system process|inflammatory response|positive regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signaling pathway|innate immune response|cellular response to lipopolysaccharide|,None,10,0.4,0.828,10,1.2,7.37,0.3,6.21,6.21,0.232,0,0,0.2,2
ENSMUSG00000026072,IL1R1,"interleukin 1 receptor, type I",extracellular region|extracellular space|nucleus|plasma membrane|cell surface|cell surface|postsynaptic density|membrane|integral component of membrane|axon|protein complex|,signal transduction|response to radiation|heat acclimation|cytokine-mediated signaling pathway|regulation of inflammatory response|interleukin-1-mediated signaling pathway|response to interleukin-1|,"protease binding|signal transducer activity|interleukin-1 receptor activity|interleukin-1 receptor activity|interleukin-1, Type I, activating receptor activity|platelet-derived growth factor receptor binding|protein binding|ionotropic glutamate receptor binding|",10,-0.7,2.19,10,-0.4,4.69,-0.4,6.19,-6.19,0.233,0,0,-1.2,0
ENSMUSG00000029387,GTF2H3,"general transcription factor IIH, polypeptide 3",core TFIIH complex|nucleus|holo TFIIH complex|,"ATP catabolic process|DNA repair|nucleotide-excision repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|cellular response to DNA damage stimulus|",protein kinase activity|DNA-dependent ATPase activity|RNA polymerase II carboxy-terminal domain kinase activity|metal ion binding|protein N-terminus binding|,9,0.3,0.477,9,0.5,6.15,0.4,6.13,6.13,0.234,0,0,0,1.2
ENSMUSG00000000827,TPD52L2,tumor protein D52-like 2,cytoplasm|perinuclear region of cytoplasm|,biological_process|,protein homodimerization activity|poly(A) RNA binding|protein heterodimerization activity|,10,1,7.25,10,0.4,0.727,0.8,6.13,6.13,0.234,0,0,0.1,1.8
ENSMUSG00000058013,11-Sep,septin 11,stress fiber|cytoplasm|cytoskeleton|cell junction|septin complex|cell projection|synapse|extracellular vesicular exosome|,cell cycle|protein heterooligomerization|cell division|,nucleotide binding|molecular_function|GTP binding|,10,0.3,3.67,10,0.3,2.75,0.3,6.1,6.1,0.236,0,0,0,1.1
ENSMUSG00000022369,MTBP,"Mdm2, transformed 3T3 cell double minute p53 binding protein",kinetochore|kinetochore|chromatin|,cell cycle|cell cycle arrest|traversing start control point of mitotic cell cycle|negative regulation of cell proliferation|protein localization to kinetochore|negative regulation of mitosis|mitotic spindle checkpoint|,protein binding|,10,1.2,8.85,10,-0.1,0.155,1,6.05,6.05,0.238,0,0,0.2,2
ENSMUSG00000003072,ATP5D,"ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit","mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)|mitochondrion|mitochondrial envelope|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|proton-transporting ATP synthase complex|proton-transporting ATP synthase complex, catalytic core F(1)|",ADP biosynthetic process|ATP catabolic process|ATP biosynthetic process|transport|ion transport|ATP synthesis coupled proton transport|proton transport|ATP metabolic process|hydrogen ion transmembrane transport|,"hydrogen ion transmembrane transporter activity|ATPase activity|ATPase activity|protein complex binding|proton-transporting ATP synthase activity, rotational mechanism|proton-transporting ATPase activity, rotational mechanism|",10,0.2,0.441,10,0.6,7.29,0.6,6.05,6.05,0.238,0,0,0.1,1.5
ENSMUSG00000016559,H3F3B,"H3 histone, family 3B",nuclear chromosome|nuclear nucleosome|nucleus|nucleus|protein complex|extracellular vesicular exosome|,osteoblast differentiation|nucleus organization|muscle cell differentiation|regulation of centromere complex assembly|negative regulation of chromosome condensation|,RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|nucleosomal DNA binding|,10,-0.7,6.24,10,-0.1,0.511,-0.7,5.93,-5.93,0.242,0,0,-1.7,1
ENSMUSG00000032702,KANK1,KN motif and ankyrin repeat domains 1,nucleus|cytoplasm|ruffle membrane|,negative regulation of neuron projection development|positive regulation of Wnt signaling pathway|negative regulation of cell migration|negative regulation of actin filament polymerization|negative regulation of Rho protein signal transduction|positive regulation of catenin import into nucleus|negative regulation of insulin receptor signaling pathway|positive regulation of wound healing|negative regulation of substrate adhesion-dependent cell spreading|negative regulation of ruffle assembly|regulation of establishment of cell polarity|negative regulation of lamellipodium morphogenesis|,beta-catenin binding|,10,-0.6,8.02,10,-0.1,0.179,-0.5,5.89,-5.89,0.243,0,0,-1.6,-0.1
ENSMUSG00000034453,POLR3B,polymerase (RNA) III (DNA directed) polypeptide B,nucleus|DNA-directed RNA polymerase III complex|,"immune system process|transcription, DNA-templated|positive regulation of interferon-beta production|innate immune response|positive regulation of innate immune response|defense response to virus|",DNA binding|DNA-directed RNA polymerase activity|transferase activity|nucleotidyltransferase activity|ribonucleoside binding|metal ion binding|,10,0.5,3.88,10,0.5,2.27,0.5,5.85,5.85,0.245,0,0,-0.2,1.7
ENSMUSG00000031715,SMARCA5,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5",condensed chromosome|nucleus|nucleus|chromatin silencing complex|NURF complex|ISWI-type complex|RSF complex|nuclear replication fork|,"chromatin silencing at rDNA|ATP catabolic process|double-strand break repair|chromatin assembly or disassembly|nucleosome assembly|chromatin remodeling|chromatin remodeling|chromatin remodeling|DNA-templated transcription, initiation|embryo development|chromatin modification|nucleosome positioning|ATP-dependent chromatin remodeling|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|","nucleotide binding|nucleic acid binding|DNA binding|chromatin binding|helicase activity|protein binding|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|ATPase activity|nucleosome binding|histone binding|",10,0.9,8.97,10,-0.3,0.0332,0.9,5.83,5.83,0.246,0,0,0.1,2
ENSMUSG00000038871,BPGM,"2,3-bisphosphoglycerate mutase",cellular_component|,glycolytic process|metabolic process|erythrocyte development|,"molecular_function|catalytic activity|bisphosphoglycerate mutase activity|bisphosphoglycerate 2-phosphatase activity|phosphoglycerate mutase activity|hydrolase activity|isomerase activity|intramolecular transferase activity, phosphotransferases|",10,1.2,9.22,10,-0.1,0.369,1.1,5.82,5.82,0.246,0,0,0.3,2
ENSMUSG00000078284,CDC73,"cell division cycle 73, Paf1/RNA polymerase II complex component",nucleus|Cdc73/Paf1 complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|endodermal cell fate commitment|transcription, DNA-templated|mRNA polyadenylation|cell cycle|negative regulation of cell proliferation|histone monoubiquitination|Wnt signaling pathway|stem cell maintenance|positive regulation of Wnt signaling pathway|positive regulation of mRNA 3'-end processing|protein destabilization|positive regulation of transcription elongation from RNA polymerase II promoter|histone H2B ubiquitination|negative regulation of myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|negative regulation of fibroblast proliferation|negative regulation of epithelial cell proliferation|cellular response to lipopolysaccharide|negative regulation of G1/S transition of mitotic cell cycle|",RNA polymerase II core binding|protein binding|,4,0.5,6.82,4,-0.1,0.23,0.5,5.79,5.79,0.247,0,0,0.1,2
ENSMUSG00000037313,TACC3,"transforming, acidic coiled-coil containing protein 3",cytoplasm|cytoplasm|centrosome|centrosome|centrosome|,microtubule cytoskeleton organization|response to hypoxia|cell proliferation|cerebral cortex development|neurogenesis|interkinetic nuclear migration|hemopoiesis|astral microtubule organization|regulation of microtubule-based process|cytoplasmic sequestering of transcription factor|regulation of cell cycle|,protein binding|protein domain specific binding|,10,0.6,6.38,10,-0.8,3.37,0.5,5.75,5.75,0.249,0,0,-1,1.6
ENSMUSG00000025651,UQCRC1,ubiquinol-cytochrome c reductase core protein 1,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex III|membrane|respiratory chain|,"mitochondrial electron transport, ubiquinol to cytochrome c|transport|oxidation-reduction process|",catalytic activity|protein binding|protein complex binding|metal ion binding|,10,0.4,3.55,10,0.4,2.49,0.4,5.73,5.73,0.25,0,0,-0.2,1.3
ENSMUSG00000062510,NSL1,"NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)","MIS12/MIND type complex|chromosome, centromeric region|kinetochore|nucleus|chromosome|",cell cycle|chromosome segregation|mitotic nuclear division|biological_process|cell division|,molecular_function|,8,1.7,4.9,9,0.4,3.43,0.3,5.73,5.73,0.25,0,0,0.1,2.8
ENSMUSG00000027079,CLP1,"CLP1, cleavage and polyadenylation factor I subunit",tRNA-intron endonuclease complex|nucleus|mRNA cleavage factor complex|,"tRNA splicing, via endonucleolytic cleavage and ligation|mRNA processing|tRNA processing|cell death|phosphorylation|cerebellar cortex development|cerebellar cortex development|targeting of mRNA for destruction involved in RNA interference|mRNA 3'-end processing|siRNA loading onto RISC involved in RNA interference|",nucleotide binding|ATP binding|kinase activity|transferase activity|ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity|polydeoxyribonucleotide kinase activity|ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity|,8,0.2,0.621,8,0.8,6.95,0.6,5.72,5.72,0.25,0,0,-1.3,2
ENSMUSG00000029430,RAN,"RAN, member RAS oncogene family",chromatin|nucleus|nucleus|cytoplasm|cytoplasm|membrane|protein complex|extracellular vesicular exosome|,ribosomal large subunit export from nucleus|ribosomal small subunit export from nucleus|GTP catabolic process|protein import into nucleus|protein export from nucleus|transport|intracellular protein transport|nucleocytoplasmic transport|cell cycle|mitotic nuclear division|signal transduction|small GTPase mediated signal transduction|protein transport|actin cytoskeleton organization|positive regulation of protein binding|cellular protein localization|cellular protein complex localization|cell division|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|protein domain specific binding|poly(A) RNA binding|,4,0.5,3.94,4,0.3,2.26,0.4,5.66,5.66,0.252,0,0,-1.1,1.9
ENSMUSG00000033156,CST10,cystatin 10 (chondrocytes),extracellular region|cytosol|extracellular vesicular exosome|,chondrocyte differentiation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|cell maturation|,cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.5,4.72,10,0.2,1.92,0.5,5.63,5.63,0.254,0,0,-0.1,1.4
ENSMUSG00000068036,MLLT4,"myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4",nucleus|cytoplasm|cytoplasm|plasma membrane|cell-cell junction|adherens junction|cell-cell adherens junction|cell-cell adherens junction|cell junction|cell junction|apical part of cell|,cell adhesion|signal transduction|,protein binding|LIM domain binding|cell adhesion molecule binding|,10,0.5,0.0843,10,0.4,5.79,0.4,5.61,5.61,0.255,0,0,-0.1,1.2
ENSMUSG00000049583,GRM5,"glutamate receptor, metabotropic 5",cytoplasm|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|postsynaptic density|postsynaptic density|membrane|integral component of membrane|neuron projection|dendritic spine|dendritic shaft|extracellular vesicular exosome|astrocyte projection|,"activation of MAPKKK activity|desensitization of G-protein coupled receptor protein signaling pathway|regulation of transcription, DNA-templated|protein phosphorylation|signal transduction|G-protein coupled receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|synaptic transmission|learning|locomotory behavior|locomotory behavior|negative regulation of locomotion|regulation of long-term neuronal synaptic plasticity|positive regulation of long-term neuronal synaptic plasticity|cognition|regulation of synaptic transmission, glutamatergic|",PLC activating G-protein coupled glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|protein binding|glutamate receptor activity|glutamate receptor activity|A2A adenosine receptor binding|,10,1.2,7.24,10,0.3,2.35,0.4,5.59,5.59,0.255,0,0,-0.3,2
ENSMUSG00000071937,ADAM25,a disintegrin and metallopeptidase domain 25 (testase 2),cellular_component|membrane|integral component of membrane|,proteolysis|multicellular organismal development|spermatogenesis|cell differentiation|,metalloendopeptidase activity|integrin binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.6,0.333,10,-0.4,5.4,-0.5,5.51,-5.51,0.259,0,0,-1.3,0.3
ENSMUSG00000024400,WDR33,WD repeat domain 33,collagen trimer|nucleus|nucleus|,mRNA processing|biological_process|,poly(A) RNA binding|,10,0.5,3.16,10,0.4,2.6,0.4,5.46,5.46,0.261,0,0,-0.5,1.3
ENSMUSG00000032177,PDE4A,"phosphodiesterase 4A, cAMP specific",nucleus|cytoplasm|cytoplasm|cytosol|perinuclear region of cytoplasm|,cAMP catabolic process|cAMP catabolic process|signal transduction|sensory perception of smell|regulation of protein kinase A signaling|cellular response to drug|regulation of cAMP-mediated signaling|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|cAMP binding|metal ion binding|",10,-0.7,2.92,10,-0.4,3.71,-0.5,5.46,-5.46,0.261,0,0,-1.5,0.1
ENSMUSG00000020974,POLE2,"polymerase (DNA directed), epsilon 2 (p59 subunit)",nucleus|epsilon DNA polymerase complex|intracellular membrane-bounded organelle|,DNA replication|DNA-dependent DNA replication|,DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|,10,0.2,0.238,10,1,6.22,0.6,5.45,5.45,0.261,0,0,0.1,1.9
ENSMUSG00000028820,SFPQ,splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated),nucleus|nucleoplasm|cytoplasm|nuclear matrix|paraspeckles|paraspeckles|,"negative regulation of transcription from RNA polymerase II promoter|alternative mRNA splicing, via spliceosome|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|cellular response to DNA damage stimulus|RNA splicing|regulation of circadian rhythm|negative regulation of circadian rhythm|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|rhythmic process|histone H3 deacetylation|",nucleotide binding|transcription regulatory region sequence-specific DNA binding|core promoter binding|nucleic acid binding|DNA binding|RNA binding|protein binding|poly(A) RNA binding|,9,0,0,9,-1.3,8.69,-1.2,5.43,-5.43,0.262,0,0,-2,0.3
ENSMUSG00000074916,CHST14,carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14,Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,carbohydrate metabolic process|carbohydrate biosynthetic process|dermatan sulfate biosynthetic process|dermatan sulfate proteoglycan metabolic process|,N-acetylgalactosamine 4-O-sulfotransferase activity|protein binding|sulfotransferase activity|transferase activity|,10,0.6,4.88,10,0.2,1.68,0.5,5.32,5.32,0.267,0,0,0,1.4
ENSMUSG00000074476,SPC24,"SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)","chromosome, centromeric region|kinetochore|nucleus|chromosome|nucleolus|Ndc80 complex|",cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,8,0.8,6.15,9,-0.3,0.9,0.7,5.3,5.3,0.268,0,0,0.1,2
ENSMUSG00000043131,MOB1A,MOB kinase activator 1A,intracellular|extracellular vesicular exosome|,hippo signaling|,metal ion binding|,10,0.4,5.62,10,0.1,0.295,0.4,5.3,5.3,0.268,0,0,0,1.2
ENSMUSG00000027208,FGF7,fibroblast growth factor 7,extracellular region|extracellular space|cell|Golgi apparatus|,ovarian follicle development|phosphatidylcholine biosynthetic process|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|phospholipid biosynthetic process|mesenchymal cell proliferation|positive regulation of keratinocyte proliferation|lung development|hair follicle morphogenesis|actin cytoskeleton reorganization|protein localization to cell surface|wound healing|surfactant homeostasis|positive regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|positive regulation of keratinocyte migration|positive regulation of cell division|branching involved in salivary gland morphogenesis|positive regulation of epithelial cell proliferation involved in lung morphogenesis|regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling|secretion by lung epithelial cell involved in lung growth|,receptor binding|fibroblast growth factor receptor binding|type 2 fibroblast growth factor receptor binding|protein binding|growth factor activity|heparin binding|chemoattractant activity|,10,-0.5,3.3,10,-1,3.37,-0.5,5.27,-5.27,0.269,0,0,-1.8,-0.1
ENSMUSG00000021771,VDAC2,voltage-dependent anion channel 2,nucleus|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial nucleoid|pore complex|extracellular vesicular exosome|,transport|ion transport|anion transport|negative regulation of protein polymerization|regulation of anion transport|transmembrane transport|negative regulation of intrinsic apoptotic signaling pathway|,nucleotide binding|protein binding|voltage-gated anion channel activity|porin activity|,10,-0.8,4.28,9,1.2,8.58,1.2,5.25,5.25,0.27,0,0,-0.9,2
ENSMUSG00000018654,IKZF1,IKAROS family zinc finger 1,nucleus|transcription factor complex|centromeric heterochromatin|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|natural killer cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|multicellular organismal development|chromatin modification|hemopoiesis|B cell differentiation|T cell differentiation|forebrain development|positive regulation of multicellular organism growth|positive regulation of multicellular organism growth|positive regulation of neutrophil differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|lymph node development|thymus development|Peyer's patch development|gland development|positive regulation of NK T cell differentiation|retina development in camera-type eye|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|protein heterodimerization activity|,10,-0.2,0.493,10,-0.3,5.18,-0.3,5.17,-5.17,0.273,0,0,-0.9,0.1
ENSMUSG00000068921,DAP3,death associated protein 3,nucleus|nucleolus|mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial ribosome|ribosome|small ribosomal subunit|ribonucleoprotein complex|,apoptotic process|apoptotic mitochondrial changes|,poly(A) RNA binding|,10,0,0,10,0.4,5.4,0.4,5.16,5.16,0.274,0,0,0,1.3
ENSMUSG00000020817,RABEP1,"rabaptin, RAB GTPase binding effector protein 1",cytoplasm|endosome|endosome|endocytic vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|,transport|endocytosis|apoptotic process|protein transport|,GTPase activator activity|protein binding|growth factor activity|protein homodimerization activity|,10,0.7,1.78,10,0.4,4.29,0.5,5.09,5.09,0.277,0,0,0,1.5
ENSMUSG00000020133,2310011J03RIK,RIKEN cDNA 2310011J03 gene,cellular_component|,biological_process|,molecular_function|,10,-0.4,4.99,10,-0.4,0.287,-0.4,5.07,-5.07,0.277,0,0,-1.2,0.4
ENSMUSG00000037465,KLF10,Kruppel-like factor 10,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|bone mineralization|somatic stem cell maintenance|positive regulation of osteoclast differentiation|",nucleic acid binding|DNA binding|metal ion binding|,10,0.4,3.16,10,-1.1,7.08,0.4,5,5,0.281,0,0,-1.9,0.8
ENSMUSG00000024507,HSD17B4,hydroxysteroid (17-beta) dehydrogenase 4,mitochondrion|peroxisome|peroxisome|peroxisomal membrane|membrane|intracellular membrane-bounded organelle|,very long-chain fatty acid metabolic process|osteoblast differentiation|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|fatty acid beta-oxidation|metabolic process|androgen metabolic process|estrogen metabolic process|very long-chain fatty-acyl-CoA metabolic process|medium-chain fatty-acyl-CoA metabolic process|oxidation-reduction process|Sertoli cell development|,"3-hydroxyacyl-CoA dehydrogenase activity|receptor binding|oxidoreductase activity|long-chain-enoyl-CoA hydratase activity|lyase activity|isomerase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity|protein homodimerization activity|17-beta-hydroxysteroid dehydrogenase (NAD+) activity|",9,0.4,1.9,9,0.3,3.39,0.3,4.99,4.99,0.281,0,0,-0.2,1.2
ENSMUSG00000025395,PRIM1,"DNA primase, p49 subunit",membrane|primosome complex|,"DNA replication|DNA replication, synthesis of RNA primer|transcription, DNA-templated|","telomerase activity|RNA helicase activity|DNA primase activity|DNA-directed RNA polymerase activity|sulfate adenylyltransferase activity|protein binding|RNA guanylyltransferase activity|tRNA guanylyltransferase activity|mannose-phosphate guanylyltransferase activity|transferase activity|nucleotidyltransferase activity|DNA/RNA helicase activity|CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity|phospholactate guanylyltransferase activity|ATP:coenzyme F420 adenylyltransferase activity|metal ion binding|UDP-N-acetylgalactosamine diphosphorylase activity|",10,0.2,1.23,10,0.5,4.63,0.5,4.97,4.97,0.282,0,0,-1.6,1.2
ENSMUSG00000024233,LYZL1,lysozyme-like 1,cellular_component|extracellular region|,biological_process|metabolic process|cell wall macromolecule catabolic process|,"molecular_function|lysozyme activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,1.2,7.4,10,0.1,0.405,1.1,4.95,4.95,0.283,0,0,0.2,2
ENSMUSG00000063524,ENO1,"enolase 1, alpha non-neuron",extracellular space|nucleus|cytoplasm|membrane|extrinsic component of plasma membrane|neuron projection|extracellular vesicular exosome|synaptic membrane|,in utero embryonic development|positive regulation of binding|cellular response to acid|,RNA binding|phosphopyruvate hydratase activity|phosphopyruvate hydratase activity|protein homodimerization activity|poly(A) RNA binding|protein heterodimerization activity|protein heterodimerization activity|,10,1.3,4.85,10,0.8,1.36,1,4.87,4.87,0.287,0,0,0.3,2
ENSMUSG00000022220,ADCY4,adenylate cyclase 4,intracellular|cytoplasm|plasma membrane|membrane|integral component of membrane|dendrite|protein complex|,cAMP biosynthetic process|cAMP biosynthetic process|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|cyclic nucleotide biosynthetic process|intracellular signal transduction|,nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|ATP binding|lyase activity|phosphorus-oxygen lyase activity|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,-0.6,6.04,10,0,0,-0.5,4.81,-4.81,0.29,0,0,-1.5,0.1
ENSMUSG00000022757,TFG,Trk-fused gene,extracellular vesicular exosome|,signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|protein binding|identical protein binding|,10,0.7,3.48,10,0.4,1.98,0.7,4.76,4.76,0.292,0,0,-1.1,1.6
ENSMUSG00000005698,CTCF,CCCTC-binding factor,"chromosome, centromeric region|condensed chromosome|nucleus|nucleus|nucleoplasm|chromosome|","negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|DNA methylation|DNA methylation|regulation of gene expression by genetic imprinting|regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|chromosome segregation|dosage compensation by inactivation of X chromosome|maintenance of DNA methylation|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|chromatin modification|nucleosome positioning|regulation of histone methylation|regulation of histone acetylation|regulation of gene expression, epigenetic|regulation of molecular function, epigenetic|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|chromatin insulator sequence binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,1.2,7.86,10,-0.1,0.295,1.2,4.74,4.74,0.293,0,0,-0.4,2
ENSMUSG00000036427,GPI1,glucose phosphate isomerase 1,extracellular region|extracellular space|nucleus|cytoplasm|cytosol|plasma membrane|plasma membrane|membrane|neuron projection|ciliary membrane|extracellular vesicular exosome|,angiogenesis|in utero embryonic development|mesoderm formation|carbohydrate metabolic process|gluconeogenesis|glycolytic process|glycolytic process|methylglyoxal biosynthetic process|erythrocyte homeostasis|glucose homeostasis|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of neuron apoptotic process|aldehyde catabolic process|glucose 6-phosphate metabolic process|glycolytic process through glucose-6-phosphate|,glucose-6-phosphate isomerase activity|glucose-6-phosphate isomerase activity|glucose-6-phosphate isomerase activity|cytokine activity|protein binding|growth factor activity|isomerase activity|intramolecular transferase activity|monosaccharide binding|,10,1.2,8.1,10,-0.7,6.65,1.1,4.72,4.72,0.294,0,0,-1.1,2
ENSMUSG00000000759,TUBGCP3,"tubulin, gamma complex associated protein 3",spindle pole|cytoplasm|centrosome|centriole|microtubule organizing center|polar microtubule|cytoskeleton|microtubule|membrane|,microtubule cytoskeleton organization|microtubule nucleation|biological_process|,gamma-tubulin binding|,9,0.6,3.08,9,0.4,2.15,0.6,4.71,4.71,0.295,0,0,0,1.6
ENSMUSG00000021823,VCL,vinculin,stress fiber|cytoplasm|cytoskeleton|actin filament|plasma membrane|cell-cell junction|adherens junction|cell-cell adherens junction|fascia adherens|focal adhesion|focal adhesion|focal adhesion|intercalated disc|actin cytoskeleton|membrane|Z disc|cell junction|sarcolemma|costamere|costamere|protein complex|extracellular vesicular exosome|,morphogenesis of an epithelium|cell adhesion|lamellipodium assembly|regulation of cell migration|adherens junction assembly|protein localization to cell surface|apical junction assembly|epithelial cell-cell adhesion|,dystroglycan binding|actin binding|structural molecule activity|protein binding|Rho GTPase binding|alpha-catenin binding|,10,0.4,3.8,10,-1.1,4.65,0.4,4.7,4.7,0.295,0,0,-1.9,0.9
ENSMUSG00000073878,GM13304,predicted gene 13304,cellular_component|,biological_process|,molecular_function|,10,-0.3,3.48,10,-0.3,1.46,-0.3,4.68,-4.68,0.296,0,0,-1.1,0.3
ENSMUSG00000095675,CCL21B,chemokine (C-C motif) ligand 21B (leucine),external side of plasma membrane|,leukocyte chemotaxis|negative regulation of myeloid cell differentiation|cell chemotaxis|,chemokine activity|chemokine activity|chemokine receptor binding|,10,-0.3,3.48,10,-0.3,1.46,-0.3,4.68,-4.68,0.296,0,0,-1.1,0.3
ENSMUSG00000000600,KRIT1,"KRIT1, ankyrin repeat containing",extracellular space|cytoplasm|cytoskeleton|microtubule|plasma membrane|cell-cell junction|membrane|cell junction|protein complex|,angiogenesis|negative regulation of endothelial cell proliferation|negative regulation of endothelial cell migration|negative regulation of angiogenesis|negative regulation of angiogenesis|positive regulation of protein binding|cell redox homeostasis|cell redox homeostasis|regulation of catalytic activity|regulation of establishment of cell polarity|regulation of establishment of cell polarity|negative regulation of endothelial cell apoptotic process|,"small GTPase regulator activity|protein binding|phosphatidylinositol-4,5-bisphosphate binding|microtubule binding|protein complex binding|",10,0.2,1.07,10,0.6,4.4,0.3,4.66,4.66,0.297,0,0,-1.5,2
ENSMUSG00000049401,OGFR,opioid growth factor receptor,nucleus|cytoplasm|membrane|,regulation of growth|,receptor activity|,10,0.9,7.83,10,-0.1,0.341,0.9,4.66,4.66,0.297,0,0,0.1,1.9
ENSMUSG00000053469,TG,thyroglobulin,extracellular region|extracellular space|extracellular space|endoplasmic reticulum|Golgi apparatus|protein complex|perinuclear region of cytoplasm|,thyroid hormone generation|thyroid hormone generation|response to pH|iodide transport|regulation of myelination|thyroid hormone metabolic process|hormone biosynthetic process|transcytosis|,receptor binding|hormone activity|protein complex binding|protein homodimerization activity|anion binding|chaperone binding|,10,0.5,4.44,10,0.2,1.41,0.4,4.66,4.66,0.297,0,0,-0.1,1.4
ENSMUSG00000091971,HSPA1A,heat shock protein 1A,nucleus|cytoplasm|cytoplasm|mitochondrion|centriole|cytosol|COP9 signalosome|inclusion body|aggresome|basolateral plasma membrane|apical plasma membrane|nuclear speck|ribonucleoprotein complex|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|blood microparticle|,telomere maintenance|ATP catabolic process|DNA repair|protein folding|response to heat|response to heat|,"protease binding|double-stranded RNA binding|ATP binding|ATPase activity|enzyme binding|heat shock protein binding|ubiquitin protein ligase binding|ATPase activity, coupled|protein binding involved in protein folding|poly(A) RNA binding|protein N-terminus binding|NF-kappaB binding|unfolded protein binding|",10,0.4,0.953,10,0.4,3.92,0.4,4.63,4.63,0.299,0,0,-0.1,1.3
ENSMUSG00000068349,GML,GPI anchored molecule like protein,cellular_component|,biological_process|,molecular_function|,10,0.2,1.17,10,1.1,4.69,0.2,4.61,4.61,0.3,0,0,0,2
ENSMUSG00000022292,RRM2B,ribonucleotide reductase M2 B (TP53 inducible),nucleus|cytoplasm|mitochondrion|mitochondrion|extracellular vesicular exosome|,kidney development|renal system process|DNA replication|mitochondrial DNA replication|DNA repair|cellular response to DNA damage stimulus|response to oxidative stress|deoxyribonucleoside diphosphate metabolic process|deoxyribonucleoside triphosphate metabolic process|deoxyribonucleotide biosynthetic process|oxidation-reduction process|negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator|,"ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor|oxidoreductase activity|metal ion binding|",10,0.5,2.86,10,0.4,2.03,0.4,4.6,4.6,0.301,0,0,-0.1,1.4
ENSMUSG00000043241,UPF2,UPF2 regulator of nonsense transcripts homolog (yeast),nucleus|cytoplasm|exon-exon junction complex|perinuclear region of cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|liver development|response to unfolded protein|organ regeneration|",None,10,1.1,7.25,10,-0.8,2.38,0.9,4.58,4.58,0.301,0,0,-0.4,2
ENSMUSG00000076747,TCRG-V5,"T cell receptor gamma, variable 5",None,None,None,10,0.6,3.64,10,0.4,1.37,0.6,4.57,4.57,0.302,0,0,-0.1,1.6
ENSMUSG00000044502,BOD1,biorientation of chromosomes in cell division 1,"chromosome, centromeric region|kinetochore|cellular_component|chromosome|cytoplasm|cytoskeleton|",cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,10,0.5,5.25,10,0.1,0.461,0.4,4.52,4.52,0.305,0,0,-0.2,1.4
ENSMUSG00000022387,BRD1,bromodomain containing 1,nucleus|MOZ/MORF histone acetyltransferase complex|,histone H3 acetylation|,histone binding|metal ion binding|,10,0.3,1.45,10,0.6,4.1,0.5,4.51,4.51,0.305,0,0,0,1.6
ENSMUSG00000049470,AFF4,"AF4/FMR2 family, member 4",nucleus|nucleus|nucleolus|mitochondrion|,"transcription, DNA-templated|regulation of transcription, DNA-templated|spermatid development|",protein binding|,10,-0.4,3.79,10,-0.7,1.89,-0.6,4.48,-4.48,0.307,0,0,-1.6,0.7
ENSMUSG00000036306,LZTS1,"leucine zipper, putative tumor suppressor 1",cytoplasm|plasma membrane|postsynaptic density|membrane|apical plasma membrane|cell junction|cell projection|neuron projection|dendritic spine|dendritic shaft|cell body|synapse|postsynaptic membrane|,cell cycle|negative regulation of macroautophagy|regulation of synaptic plasticity|regulation of dendrite morphogenesis|,None,10,-0.5,2.62,10,-0.5,2.12,-0.5,4.47,-4.47,0.308,0,0,-1.5,0.1
ENSMUSG00000036526,CARD11,"caspase recruitment domain family, member 11",immunological synapse|cytoplasm|plasma membrane|plasma membrane|membrane|T cell receptor complex|membrane raft|,positive regulation of cytokine production|signal transduction|positive regulation of B cell proliferation|T cell costimulation|positive regulation of T cell proliferation|regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|thymic T cell selection|positive regulation of interleukin-2 biosynthetic process|regulation of B cell differentiation|regulation of T cell differentiation|regulation of immune response|positive regulation of T cell activation|positive regulation of NF-kappaB transcription factor activity|,protein binding|CARD domain binding|,10,0.4,3.6,10,0.3,1.27,0.4,4.46,4.46,0.308,0,0,-0.3,1.4
ENSMUSG00000040276,PACSIN1,protein kinase C and casein kinase substrate in neurons 1,cell|cytoplasm|cytoplasm|plasma membrane|membrane|cell junction|COPI-coated vesicle|cytoplasmic vesicle|ruffle membrane|cell projection|neuron projection|axon terminus|synapse|perinuclear region of cytoplasm|,endocytosis|cytoskeleton organization|actin filament organization|signal transduction|negative regulation of endocytosis|synaptic vesicle endocytosis|neuron development|neuron projection morphogenesis|protein localization to membrane|establishment of protein localization to plasma membrane|membrane tubulation|membrane tubulation|positive regulation of dendrite development|,protein binding|phospholipid binding|phospholipid binding|cytoskeletal protein binding|lipid binding|,10,0,0,10,0.6,5.83,0.3,4.44,4.44,0.309,0,0,-0.1,1.4
ENSMUSG00000015120,UBE2I,ubiquitin-conjugating enzyme E2I,fibrillar center|nucleus|cytoplasm|nuclear body|nuclear body|PML body|dendrite|synapse|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cellular protein modification process|cell cycle|chromosome segregation|mitotic nuclear division|multicellular organismal development|regulation of receptor activity|viral process|protein ubiquitination|protein sumoylation|positive regulation of intracellular steroid hormone receptor signaling pathway|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of transcription, DNA-templated|positive regulation of sequence-specific DNA binding transcription factor activity|cell division|","nucleotide binding|ubiquitin-protein transferase activity|protein binding|ATP binding|protein C-terminus binding|transcription factor binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|SUMO ligase activity|enzyme binding|HLH domain binding|bHLH transcription factor binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|RING-like zinc finger domain binding|",10,0.7,5.25,10,0.2,0.97,0.6,4.43,4.43,0.31,0,0,-0.1,2
ENSMUSG00000026182,TNP1,transition protein 1,nucleosome|male germ cell nucleus|male germ cell nucleus|nucleus|nucleus|chromosome|,multicellular organismal development|spermatogenesis|cell differentiation|,DNA binding|,10,0.5,4.61,10,0.2,1.13,0.4,4.43,4.43,0.31,0,0,-0.2,1.5
ENSMUSG00000041624,GUCY1A2,"guanylate cyclase 1, soluble, alpha 2",membrane|integral component of membrane|,cGMP biosynthetic process|positive regulation of cGMP biosynthetic process|,nucleotide binding|guanylate cyclase activity|lyase activity|,10,-0.4,4.79,10,0.8,3,-0.4,4.43,-4.43,0.31,0,0,-1.3,1.3
ENSMUSG00000028893,SESN2,sestrin 2,intracellular|nucleus|cytoplasm|mitochondrion|,regulation of protein phosphorylation|fatty acid beta-oxidation|autophagy|mitochondrion organization|response to glucose|response to glucose|mitochondrial DNA metabolic process|response to insulin|response to insulin|glucose homeostasis|protein kinase B signaling|glucose import|triglyceride homeostasis|regulation of gluconeogenesis involved in cellular glucose homeostasis|regulation of response to reactive oxygen species|regulation of cAMP-dependent protein kinase activity|,None,10,1.2,7.49,10,-0.2,0.916,1.2,4.42,4.42,0.311,0,0,0.1,2
ENSMUSG00000038023,ATP6V0A2,"ATPase, H+ transporting, lysosomal V0 subunit A2","vacuolar proton-transporting V-type ATPase, V0 domain|acrosomal vesicle|cytoplasm|lysosomal membrane|endosome|plasma membrane|membrane|integral component of membrane|proton-transporting V-type ATPase, V0 domain|",transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|,protein binding|hydrogen ion transmembrane transporter activity|,10,-1.6,7.92,10,0,0,-0.2,4.42,-4.42,0.311,0,0,-2.9,0.3
ENSMUSG00000046731,KCTD11,potassium channel tetramerisation domain containing 11,cytoplasm|,cell cycle|multicellular organismal development|nervous system development|negative regulation of neuroblast proliferation|cell differentiation|regulation of growth|regulation of cell proliferation|positive regulation of neuron differentiation|negative regulation of smoothened signaling pathway|protein homooligomerization|,molecular_function|,10,1.2,7.61,10,0.1,0.0404,1.1,4.41,4.41,0.311,0,0,0.2,2
ENSMUSG00000035949,FBXW2,F-box and WD-40 domain protein 2,cytoplasm|,None,protein binding|,10,-0.4,2.23,10,0.7,4.85,0.4,4.4,4.4,0.312,0,0,-0.8,1.5
ENSMUSG00000003131,PAFAH1B2,"platelet-activating factor acetylhydrolase, isoform 1b, subunit 2",nucleolus|cytoplasm|cytoplasm|cytosol|plasma membrane|extracellular vesicular exosome|,lipid metabolic process|cellular component movement|spermatogenesis|spermatogenesis|lipid catabolic process|positive regulation of macroautophagy|,1-alkyl-2-acetylglycerophosphocholine esterase activity|protein binding|hydrolase activity|protein homodimerization activity|protein heterodimerization activity|platelet-activating factor acetyltransferase activity|,10,-0.3,4.21,10,-0.2,0.868,-0.3,4.39,-4.39,0.313,0,0,-1.2,0.8
ENSMUSG00000024346,PFDN1,prefoldin 1,cellular_component|prefoldin complex|,protein folding|telencephalon development|cerebellum development|actin cytoskeleton organization|B cell activation|,molecular_function|unfolded protein binding|,10,0.2,0.964,10,0.5,4.7,0.4,4.38,4.38,0.313,0,0,-0.2,1.3
ENSMUSG00000079478,SSSCA1,Sjogren's syndrome/scleroderma autoantigen 1 homolog (human),cellular_component|,biological_process|,protein binding|identical protein binding|,10,0.4,5.62,10,0.1,0.325,0.4,4.37,4.37,0.314,0,0,-0.2,1.4
ENSMUSG00000028329,XPA,"xeroderma pigmentosum, complementation group A",intracellular|nucleus|nucleus|DNA replication factor A complex|cytoplasm|Golgi apparatus|intercellular bridge|,DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|response to oxidative stress|intrinsic apoptotic signaling pathway in response to DNA damage|response to UV|response to toxic substance|multicellular organism growth|,DNA binding|damaged DNA binding|protein domain specific binding|protein homodimerization activity|metal ion binding|,10,-0.4,5.4,10,0.2,0.595,-0.4,4.35,-4.35,0.315,0,0,-1.5,0.3
ENSMUSG00000021619,ATG10,autophagy related 10,intracellular|intracellular|cytoplasm|,protein lipidation|transport|autophagy|autophagy|protein transport|positive regulation of protein modification process|protein modification by small protein conjugation|protein modification by small protein conjugation|autophagy in response to ER overload|,"protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|Atg12 ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,0.556,10,-0.5,5.59,-0.4,4.33,-4.33,0.316,0,0,-1.4,0.7
ENSMUSG00000055994,NOD2,nucleotide-binding oligomerization domain containing 2,intracellular|cytoplasm|cytoplasm|cytoplasm|cytosol|cytoskeleton|plasma membrane|COP9 signalosome|cell surface|vesicle|protein complex|,innate immune response in mucosa|activation of immune response|cytokine production involved in immune response|immune system process|immunoglobulin production involved in immunoglobulin mediated immune response|positive regulation of dendritic cell antigen processing and presentation|negative regulation of T cell mediated immunity|positive regulation of dendritic cell cytokine production|positive regulation of type 2 immune response|negative regulation of inflammatory response to antigenic stimulus|positive regulation of humoral immune response mediated by circulating immunoglobulin|defense response|inflammatory response|positive regulation of antibacterial peptide biosynthetic process|positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|signal transduction|positive regulation of cell proliferation|detection of biotic stimulus|detection of bacterium|maintenance of gastrointestinal epithelium|positive regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|response to peptidoglycan|response to peptidoglycan|response to muramyl dipeptide|response to muramyl dipeptide|response to muramyl dipeptide|response to lipopolysaccharide|detection of muramyl dipeptide|negative regulation of interferon-gamma production|negative regulation of interleukin-12 production|negative regulation of interleukin-12 production|negative regulation of interleukin-18 production|negative regulation of interleukin-2 production|negative regulation of tumor necrosis factor production|positive regulation of interleukin-1 beta production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-12 production|positive regulation of interleukin-17 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of stress-activated MAPK cascade|positive regulation of stress-activated MAPK cascade|negative regulation of toll-like receptor 2 signaling pathway|activation of MAPK activity involved in innate immune response|intracellular signal transduction|defense response to bacterium|regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to exogenous dsRNA|positive regulation of MAPK cascade|positive regulation of phosphatidylinositol 3-kinase activity|negative regulation of growth of symbiont in host|innate immune response|positive regulation of innate immune response|positive regulation of Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|positive regulation of JNK cascade|positive regulation of epithelial cell proliferation|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|regulation of inflammatory response|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of phagocytosis|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|positive regulation of B cell activation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein oligomerization|positive regulation of oxidoreductase activity|positive regulation of nitric-oxide synthase biosynthetic process|positive regulation of prostaglandin-endoperoxide synthase activity|positive regulation of ERK1 and ERK2 cascade|nucleotide-binding oligomerization domain containing 2 signaling pathway|nucleotide-binding oligomerization domain containing 2 signaling pathway|cellular response to peptidoglycan|cellular response to muramyl dipeptide|macrophage inflammatory protein-1 alpha production|regulation of neutrophil chemotaxis|negative regulation of macrophage apoptotic process|positive regulation of prostaglandin-E synthase activity|,"nucleotide binding|protein binding|ATP binding|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|enzyme binding|protein kinase binding|muramyl dipeptide binding|muramyl dipeptide binding|peptidoglycan binding|peptidoglycan binding|CARD domain binding|",10,-0.5,1.81,10,-0.4,2.79,-0.4,4.32,-4.32,0.317,0,0,-1.3,0.6
ENSMUSG00000031010,USP9X,"ubiquitin specific peptidase 9, X chromosome",cytoplasm|cytoplasm|membrane|growth cone|apical part of cell|,in utero embryonic development|neuron migration|proteolysis|ubiquitin-dependent protein catabolic process|cell cycle|chromosome segregation|mitotic nuclear division|transforming growth factor beta receptor signaling pathway|post-embryonic development|protein deubiquitination|cerebellar cortex structural organization|hippocampus development|BMP signaling pathway|axon extension|axon extension|cell division|cellular response to transforming growth factor beta stimulus|neuron projection extension|,protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|co-SMAD binding|,10,1,3.23,10,0.9,1.33,1,4.3,4.3,0.318,0,0,0.1,2
ENSMUSG00000027966,COL11A1,"collagen, type XI, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type XI trimer|extracellular matrix|extracellular matrix|,cartilage condensation|chondrocyte development|heart morphogenesis|proteoglycan metabolic process|visual perception|sensory perception of sound|collagen fibril organization|collagen fibril organization|tendon development|tendon development|inner ear morphogenesis|embryonic skeletal system morphogenesis|skeletal system morphogenesis|detection of mechanical stimulus involved in sensory perception of sound|cartilage development|ventricular cardiac muscle tissue morphogenesis|,molecular_function|extracellular matrix structural constituent|metal ion binding|,10,1,3.18,10,1,1.31,1,4.24,4.24,0.321,0,0,0,2
ENSMUSG00000026110,MGAT4A,"mannoside acetylglucosaminyltransferase 4, isoenzyme A",extracellular region|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,carbohydrate metabolic process|,"alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|metal ion binding|",10,-0.8,6.61,10,-0.1,0.327,-0.2,4.24,-4.24,0.321,0,0,-1.8,-0.1
ENSMUSG00000043263,PYHIN1,"pyrin and HIN domain family, member 1",nucleus|nucleolus|cytoplasm|membrane|,cellular response to interferon-beta|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,10,0.3,2.22,10,0.5,3.24,0.5,4.23,4.23,0.322,0,0,-0.1,1.5
ENSMUSG00000021338,LRRC16A,leucine rich repeat containing 16A,nucleus|cytoplasm|lamellipodium|lamellipodium|filamentous actin|extracellular vesicular exosome|,cell migration|lamellipodium assembly|positive regulation of cell migration|positive regulation of cell migration|positive regulation of actin filament polymerization|ruffle organization|urate metabolic process|positive regulation of stress fiber assembly|positive regulation of stress fiber assembly|barbed-end actin filament uncapping|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of lamellipodium organization|positive regulation of lamellipodium organization|negative regulation of barbed-end actin filament capping|,protein complex binding|protein complex binding|,10,-0.6,0.434,10,-0.4,4.22,-0.4,4.19,-4.19,0.324,0,0,-1.4,0.1
ENSMUSG00000069135,FGFR1OP,Fgfr1 oncogene partner,nucleus|cytoplasm|centrosome|microtubule organizing center|cytoskeleton|perinuclear region of cytoplasm|,negative regulation of protein kinase activity|positive regulation of cell proliferation|positive regulation of cell growth|positive regulation of cell migration|microtubule anchoring|negative regulation of protein tyrosine kinase activity|,protein kinase binding|protein tyrosine kinase inhibitor activity|protein homodimerization activity|,10,0,0,10,0.5,5.87,0.4,4.18,4.18,0.325,0,0,-0.1,1.4
ENSMUSG00000020432,TCN2,transcobalamin 2,extracellular region|extracellular space|extracellular vesicular exosome|,transport|ion transport|cobalt ion transport|cobalamin metabolic process|cobalamin transport|,cobalamin binding|cobalamin binding|metal ion binding|,10,0.2,1.59,10,0.5,3.51,0.4,4.16,4.16,0.326,0,0,-0.1,1.5
ENSMUSG00000062203,GSPT1,G1 to S phase transition 1,None,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|translation|translational termination|protein methylation|",nucleotide binding|translation release factor activity|GTPase activity|GTP binding|poly(A) RNA binding|,10,-0.8,5.11,10,0.3,2.14,0.3,4.14,4.14,0.327,0,0,-1.8,0.7
ENSMUSG00000066043,PHACTR4,phosphatase and actin regulator 4,intracellular|cytoplasm|lamellipodium|cell projection|,neural crest cell migration|neural tube closure|Rho protein signal transduction|multicellular organismal development|nervous system development|actin cytoskeleton organization|positive regulation of catalytic activity|positive regulation of catalytic activity|enteric nervous system development|regulation of cell cycle|closure of optic fissure|negative regulation of integrin-mediated signaling pathway|,actin binding|protein phosphatase inhibitor activity|protein phosphatase 1 binding|protein phosphatase type 1 activator activity|protein phosphatase type 1 activator activity|,10,-1,3.7,10,0.3,3.79,0.3,4.1,4.1,0.33,0,0,-1.9,0.9
ENSMUSG00000047126,CLTC,"clathrin, heavy polypeptide (Hc)",mitochondrion|spindle|coated pit|membrane|membrane coat|clathrin coat|clathrin coat of trans-Golgi network vesicle|clathrin coat of coated pit|clathrin-coated vesicle|T-tubule|cytoplasmic vesicle|Myb complex|sarcolemma|protein complex|extracellular vesicular exosome|clathrin complex|,osteoblast differentiation|intracellular protein transport|receptor-mediated endocytosis|Golgi organization|mitotic nuclear division|vesicle-mediated transport|receptor internalization|transferrin transport|spindle assembly involved in mitosis|negative regulation of hyaluronan biosynthetic process|,double-stranded RNA binding|structural molecule activity|protein C-terminus binding|ankyrin binding|heat shock protein binding|clathrin light chain binding|peptide binding|poly(A) RNA binding|,9,-0.4,1.96,6,-0.6,2.44,-0.5,4.1,-4.1,0.33,0,0,-1.7,0.3
ENSMUSG00000062270,MORF4L1,mortality factor 4 like 1,nucleus|Sin3 complex|NuA4 histone acetyltransferase complex|,"double-strand break repair via homologous recombination|DNA repair|DNA recombination|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell proliferation|chromatin modification|histone deacetylation|regulation of growth|histone H4 acetylation|histone H2A acetylation|",chromatin binding|protein binding|protein N-terminus binding|,10,-0.2,0.572,10,0.8,6.33,0.7,4.09,4.09,0.331,0,0,-0.2,1.7
ENSMUSG00000028973,ABCB8,"ATP-binding cassette, sub-family B (MDR/TAP), member 8",nucleus|nucleolus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,ATP catabolic process|transport|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,-0.3,2.21,10,-0.4,2.14,-0.4,4.08,-4.08,0.331,0,0,-1.4,0.6
ENSMUSG00000036403,CEP135,centrosomal protein 135,cytoplasm|centrosome|centriole|cytoskeleton|,centriole replication|centriole-centriole cohesion|,protein C-terminus binding|,10,0.3,1.25,10,0.6,3.78,0.4,4.06,4.06,0.333,0,0,-0.1,1.4
ENSMUSG00000020317,THEG,testicular haploid expressed gene,nucleus|cytoplasm|,multicellular organismal development|spermatogenesis|cell differentiation|,protein binding|,10,0.3,2.51,10,1.1,3.07,0.2,4.03,4.03,0.334,0,0,-0.2,1.8
ENSMUSG00000090812,SAMD15,sterile alpha motif domain containing 15,cellular_component|,biological_process|,molecular_function|,10,0.5,5.37,10,-0.9,1.99,0.5,4.03,4.03,0.334,0,0,-1.3,1.5
ENSMUSG00000038366,LASP1,LIM and SH3 protein 1,cytoplasm|cytoskeleton|focal adhesion|cortical actin cytoskeleton|extracellular vesicular exosome|,transport|ion transport|ion transmembrane transport|,actin binding|protein binding|zinc ion binding|ion transmembrane transporter activity|metal ion binding|actin filament binding|,10,0.3,2.62,10,0.3,1.66,0.3,4.03,4.03,0.334,0,0,-0.2,1.2
ENSMUSG00000005413,HMOX1,heme oxygenase (decycling) 1,nucleus|nucleus|nucleolus|endoplasmic reticulum|cytosol|caveola|membrane|intracellular membrane-bounded organelle|,angiogenesis|wound healing involved in inflammatory response|heme oxidation|apoptotic process|response to oxidative stress|small GTPase mediated signal transduction|regulation of blood pressure|cell death|negative regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of muscle cell apoptotic process|negative regulation of mast cell cytokine production|erythrocyte homeostasis|regulation of transcription from RNA polymerase II promoter in response to iron|response to nicotine|intracellular signal transduction|heme catabolic process|heme metabolic process|response to hydrogen peroxide|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of mast cell degranulation|negative regulation of DNA binding|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of neuron apoptotic process|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|response to estrogen|positive regulation of angiogenesis|positive regulation of smooth muscle cell proliferation|negative regulation of smooth muscle cell proliferation|regulation of sequence-specific DNA binding transcription factor activity|protein homooligomerization|iron ion homeostasis|oxidation-reduction process|cellular response to arsenic-containing substance|cellular response to cadmium ion|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|,heme oxygenase (decyclizing) activity|phospholipase D activity|signal transducer activity|oxidoreductase activity|enzyme binding|heme binding|protein homodimerization activity|metal ion binding|,10,-0.2,1.72,10,-0.2,2.56,-0.2,4.03,-4.03,0.334,0,0,-1.1,0.3
ENSMUSG00000039217,IL18,interleukin 18,extracellular region|extracellular space|extracellular space|cytoplasm|apical plasma membrane|extracellular vesicular exosome|,MAPK cascade|angiogenesis|angiogenesis|response to hypoxia|inflammatory response|inflammatory response|immune response|extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of gene expression|positive regulation of smooth muscle cell migration|natural killer cell activation|regulation of cell adhesion|regulation of cell adhesion|sleep|sleep|lipopolysaccharide-mediated signaling pathway|positive regulation of chemokine production|positive regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of interferon-gamma production|positive regulation of interferon-gamma production|positive regulation of interleukin-17 production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|positive regulation of natural killer cell proliferation|positive regulation of superoxide anion generation|positive regulation of collagen biosynthetic process|negative regulation of neutrophil apoptotic process|T-helper 1 type immune response|T-helper 1 type immune response|interferon-gamma biosynthetic process|positive regulation of activated T cell proliferation|positive regulation of activated T cell proliferation|interleukin-13 biosynthetic process|positive regulation of NF-kappaB import into nucleus|positive regulation of apoptotic process|positive regulation of vascular permeability|positive regulation of neuron apoptotic process|positive regulation of smooth muscle cell proliferation|negative regulation of peptidyl-tyrosine phosphorylation|detection of mechanical stimulus involved in sensory perception of pain|positive regulation of NK T cell proliferation|cellular response to peptide hormone stimulus|cellular response to organic cyclic compound|positive regulation of male germ cell proliferation|positive regulation of blood vessel remodeling|,cytokine activity|,10,-0.5,2.97,10,0.4,3.17,-0.7,4.03,-4.03,0.334,0,0,-1.9,0.7
ENSMUSG00000046755,KIF2B,kinesin family member 2B,"chromosome, centromeric region|kinetochore|nucleus|chromosome|nucleolus|cytoplasm|cytoskeleton|kinesin complex|microtubule|microtubule cytoskeleton|",microtubule-based movement|microtubule depolymerization|cell cycle|mitotic nuclear division|cell division|regulation of chromosome segregation|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,1.1,4.43,10,0,0,0.9,4,4,0.336,0,0,0.1,2
ENSMUSG00000079563,PGLYRP2,peptidoglycan recognition protein 2,extracellular region|membrane|extracellular vesicular exosome|,pattern recognition receptor signaling pathway|immune system process|peptidoglycan catabolic process|detection of bacterium|negative regulation of interferon-gamma production|negative regulation of natural killer cell differentiation involved in immune response|growth of symbiont in host|regulation of inflammatory response|defense response to Gram-positive bacterium|,zinc ion binding|N-acetylmuramoyl-L-alanine amidase activity|peptidoglycan receptor activity|hydrolase activity|peptidoglycan binding|metal ion binding|,10,0.2,0.614,10,0.4,4.1,0.3,3.98,3.98,0.337,0,0,-0.2,1.2
ENSMUSG00000031503,COL4A2,"collagen, type IV, alpha 2",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type IV trimer|basement membrane|extracellular matrix|intracellular membrane-bounded organelle|extracellular vesicular exosome|,"angiogenesis|transcription, DNA-templated|negative regulation of angiogenesis|",extracellular matrix structural constituent|,10,0.2,1.26,10,0.5,3.46,0.3,3.96,3.96,0.339,0,0,-0.1,1.3
ENSMUSG00000036940,KDM1A,lysine (K)-specific demethylase 1A,nuclear chromatin|nuclear chromatin|nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|protein demethylation|multicellular organismal development|cell proliferation|regulation of primitive erythrocyte differentiation|chromatin modification|pituitary gland development|granulocyte differentiation|negative regulation of protein binding|histone H3-K9 demethylation|histone H3-K9 demethylation|regulation of transcription by chromatin organization|histone H3-K4 demethylation|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of erythrocyte differentiation|positive regulation of megakaryocyte differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hormone biosynthetic process|positive regulation of sequence-specific DNA binding transcription factor activity|negative regulation of histone H3-K4 methylation|negative regulation of histone H3-K9 methylation|muscle cell development|oxidation-reduction process|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of neural precursor cell proliferation|positive regulation of stem cell proliferation|",RNA polymerase II transcription factor binding|p53 binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|transcription factor binding|N-ethylmaleimide reductase activity|oxidoreductase activity|enzyme binding|enzyme binding|ligand-dependent nuclear receptor transcription coactivator activity|demethylase activity|histone demethylase activity|histone demethylase activity (H3-K4 specific)|histone demethylase activity (H3-K9 specific)|histone demethylase activity (H3-dimethyl-K4 specific)|MRF binding|MRF binding|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|transcription regulatory region DNA binding|flavin adenine dinucleotide binding|androgen receptor binding|epoxyqueuosine reductase activity|,9,0.2,0.704,9,0.4,3.72,0.3,3.95,3.95,0.339,0,0,-0.2,1.5
ENSMUSG00000021224,NUMB,numb gene homolog (Drosophila),nucleus|cytoplasm|early endosome|membrane|basolateral plasma membrane|extrinsic component of plasma membrane|apical part of cell|apical part of cell|,multicellular organismal development|nervous system development|neuroblast proliferation|axonogenesis|axonogenesis|lateral ventricle development|neuroblast division in subventricular zone|positive regulation of polarized epithelial cell differentiation|forebrain development|adherens junction organization|regulation of neuron differentiation|negative regulation of Notch signaling pathway|positive regulation of neurogenesis|positive regulation of dendrite morphogenesis|lung epithelial cell differentiation|,protein binding|beta-catenin binding|alpha-catenin binding|cadherin binding|,10,0.1,0.434,10,0.8,5.76,0.8,3.94,3.94,0.34,0,0,-0.1,1.8
ENSMUSG00000025804,CCR1,chemokine (C-C motif) receptor 1,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|neuronal cell body|,calcium ion transport|cellular calcium ion homeostasis|exocytosis|chemotaxis|inflammatory response|immune response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|cell-cell signaling|metabolic process|negative regulation of gene expression|myeloid cell differentiation|negative regulation of bone mineralization|leukocyte chemotaxis|leukocyte chemotaxis|positive regulation of osteoclast differentiation|negative regulation of innate immune response|positive regulation of calcium ion transport|chemokine-mediated signaling pathway|chemokine-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade|positive regulation of monocyte chemotaxis|,phosphatidylinositol phospholipase C activity|signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|C-C chemokine receptor activity|C-C chemokine binding|chemokine (C-C motif) ligand 7 binding|chemokine (C-C motif) ligand 5 binding|,10,-0.3,2.5,10,-0.4,1.72,-0.3,3.94,-3.94,0.34,0,0,-1.3,0.2
ENSMUSG00000004667,POLR2E,polymerase (RNA) II (DNA directed) polypeptide E,"nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase I complex|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase I activity|RNA polymerase II activity|RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|,9,0.5,3.83,8,0.8,0.582,0.6,3.93,3.93,0.341,0,0,-0.2,1.8
ENSMUSG00000041491,CEP78,centrosomal protein 78,cytoplasm|centrosome|cytoskeleton|,biological_process|,molecular_function|,10,0.5,3.72,10,0.2,0.937,0.5,3.84,3.84,0.346,0,0,-0.1,1.5
ENSMUSG00000038843,GCNT1,"glucosaminyl (N-acetyl) transferase 1, core 2",extracellular space|Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|Golgi cisterna|,glycoprotein biosynthetic process|tissue morphogenesis|leukocyte tethering or rolling|cell adhesion molecule production|kidney morphogenesis|,"beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,1.4,2.6,10,-0.9,5.13,-0.4,3.8,-3.8,0.349,0,0,-2,1.3
ENSMUSG00000029415,SDAD1,SDA1 domain containing 1,nucleus|nucleolus|,ribosomal large subunit export from nucleus|transport|biological_process|protein transport|actin cytoskeleton organization|ribosome biogenesis|ribosomal large subunit biogenesis|,molecular_function|,9,1.5,2.61,7,-0.3,1.62,-0.3,3.79,-3.79,0.35,0,0,-1.2,2.7
ENSMUSG00000022085,PEBP4,phosphatidylethanolamine binding protein 4,cellular_component|lysosome|,biological_process|,molecular_function|,10,-0.4,3.01,10,-0.2,1.15,-0.3,3.77,-3.77,0.351,0,0,-1.2,0.8
ENSMUSG00000019794,KATNA1,katanin p60 (ATPase-containing) subunit A1,spindle pole|nucleus|cytoplasm|lipid particle|centrosome|spindle|cytoskeleton|microtubule|plasma membrane|axon|axon|growth cone|midbody|neuronal cell body|,microtubule bundle formation|neuron migration|ATP catabolic process|cell cycle|mitotic nuclear division|meiotic nuclear division|protein localization|negative regulation of neuron projection development|cytoplasmic microtubule organization|microtubule severing|microtubule severing|cell division|mitotic interphase|,nucleotide binding|protein binding|ATP binding|microtubule binding|microtubule-severing ATPase activity|hydrolase activity|ATPase activity|dynein binding|protein heterodimerization activity|,10,0.3,2.19,10,0.4,1.9,0.3,3.76,3.76,0.352,0,0,-1,1.4
ENSMUSG00000024365,CYP21A1,"cytochrome P450, family 21, subfamily a, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,steroid biosynthetic process|C21-steroid hormone biosynthetic process|mineralocorticoid biosynthetic process|progesterone metabolic process|oxidation-reduction process|,"monooxygenase activity|steroid 21-monooxygenase activity|steroid binding|iron ion binding|lipid binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|",10,0.7,3.19,10,0.1,1.01,0.7,3.76,3.76,0.352,0,0,-0.2,1.8
ENSMUSG00000079184,MPHOSPH8,M-phase phosphoprotein 8,nuclear nucleosome|nucleus|nuclear heterochromatin|nucleolus|cytoplasm|plasma membrane|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of DNA methylation|negative regulation of transcription, DNA-templated|",methylated histone binding|,10,-0.5,2.48,10,-0.5,1.5,-0.5,3.74,-3.74,0.353,0,0,-1.6,0.3
ENSMUSG00000059669,TAF1B,"TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B",RNA polymerase I transcription factor complex|nucleus|extracellular vesicular exosome|RNA polymerase I core factor complex|,"RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase I promoter|transcription from RNA polymerase I promoter|",RNA polymerase I CORE element sequence-specific DNA binding|RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity|DNA binding|protein binding|metal ion binding|,10,0.7,4.72,10,-0.8,1.42,0.5,3.74,3.74,0.353,0,0,-1.1,1.8
ENSMUSG00000023051,TARBP2,TAR (HIV) RNA binding protein 2,nucleus|cytoplasm|RISC complex|,regulation of translation|production of siRNA involved in RNA interference|targeting of mRNA for destruction involved in RNA interference|gene silencing by RNA|pre-miRNA processing|miRNA loading onto RISC involved in gene silencing by miRNA|positive regulation of viral genome replication|regulation of viral transcription|negative regulation of defense response to virus by host|,RNA binding|double-stranded RNA binding|protein binding|siRNA binding|protein homodimerization activity|,10,0.3,1.54,10,0.2,2.42,0.3,3.72,3.72,0.354,0,0,-0.2,1.3
ENSMUSG00000061731,EXT1,exostoses (multiple) 1,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|intrinsic component of endoplasmic reticulum membrane|,"ossification|glycosaminoglycan biosynthetic process|gastrulation|axon guidance|axon guidance|brain development|endoderm development|mesoderm development|heparan sulfate proteoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process|olfactory bulb development|cellular polysaccharide biosynthetic process|embryonic skeletal joint development|","acetylglucosaminyltransferase activity|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|protein homodimerization activity|protein heterodimerization activity|glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity|",10,0.7,1.39,10,0.3,3.77,0.4,3.72,3.72,0.354,0,0,-0.1,1.6
ENSMUSG00000039959,HIP1,huntingtin interacting protein 1,nucleus|cytoplasm|Golgi apparatus|membrane|clathrin-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|endocytosis|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell death|cell differentiation|regulation of apoptotic process|positive regulation of receptor-mediated endocytosis|positive regulation of receptor-mediated endocytosis|clathrin coat assembly|apoptotic signaling pathway|",actin binding|protein binding|phospholipid binding|clathrin binding|phosphatidylinositol binding|,10,0.3,3.29,10,0.2,1.03,0.2,3.71,3.71,0.355,0,0,-0.4,1.2
ENSMUSG00000031821,GINS2,GINS complex subunit 2 (Psf2 homolog),cellular_component|nucleus|,DNA replication|biological_process|,molecular_function|,10,0.5,3.76,10,-0.6,1.23,0.5,3.7,3.7,0.355,0,0,-0.8,1.7
ENSMUSG00000059481,PLG,plasminogen,extracellular region|extracellular space|plasma membrane|cell surface|extrinsic component of plasma membrane|extrinsic component of external side of plasma membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|blood microparticle|,proteolysis|blood coagulation|hemostasis|negative regulation of cell-substrate adhesion|negative regulation of angiogenesis|extracellular matrix disassembly|tissue regeneration|fibrinolysis|myoblast differentiation|muscle cell cellular homeostasis|tissue remodeling|proteolysis involved in cellular protein catabolic process|negative regulation of fibrinolysis|positive regulation of fibrinolysis|trophoblast giant cell differentiation|labyrinthine layer blood vessel development|mononuclear cell migration|,catalytic activity|endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|protein domain specific binding|apolipoprotein binding|,10,0.2,0.8,10,0.3,3.33,0.2,3.69,3.69,0.356,0,0,-0.2,1.4
ENSMUSG00000042333,TNFRSF14,"tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)",external side of plasma membrane|,positive regulation of cytokine secretion involved in immune response|negative regulation of alpha-beta T cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|positive regulation of T cell migration|,protein binding|ubiquitin protein ligase binding|,10,1,5.58,10,0.2,0.468,0.3,3.69,3.69,0.356,0,0,-0.1,2
ENSMUSG00000044542,PROP1,paired like homeodomain factor 1,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|blood vessel development|regulation of transcription, DNA-templated|organ morphogenesis|dorsal/ventral pattern formation|cell migration|hypothalamus cell differentiation|adenohypophysis development|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|gland development|hypophysis morphogenesis|canonical Wnt signaling pathway|somatotropin secreting cell differentiation|",DNA binding|chromatin binding|protein binding|beta-catenin binding|protein C-terminus binding|sequence-specific DNA binding|,10,-1,6,10,0.2,0.539,-0.9,3.67,-3.67,0.357,0,0,-2,0
ENSMUSG00000053475,TNFAIP6,tumor necrosis factor alpha induced protein 6,extracellular space|,cell adhesion|positive regulation of cell migration|,hyaluronic acid binding|,10,0,0,10,-1.6,6.79,-0.2,3.67,-3.67,0.357,0,0,-2.9,0
ENSMUSG00000005161,PRDX2,peroxiredoxin 2,cytoplasm|mitochondrion|cytosol|extracellular vesicular exosome|,activation of MAPK activity|respiratory burst involved in inflammatory response|response to oxidative stress|response to oxidative stress|regulation of hydrogen peroxide metabolic process|removal of superoxide radicals|removal of superoxide radicals|positive regulation of blood coagulation|negative regulation of lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|response to lipopolysaccharide|cellular response to oxidative stress|T cell proliferation|hydrogen peroxide metabolic process|hydrogen peroxide catabolic process|regulation of apoptotic process|negative regulation of neuron apoptotic process|negative regulation of T cell differentiation|thymus development|homeostasis of number of cells|oxidation-reduction process|negative regulation of reactive oxygen species metabolic process|negative regulation of extrinsic apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,peroxidase activity|protein binding|thioredoxin peroxidase activity|thioredoxin peroxidase activity|thioredoxin peroxidase activity|selenium binding|antioxidant activity|oxidoreductase activity|peroxiredoxin activity|,10,0.5,3.46,10,-1.2,6.85,-1.1,3.66,-3.66,0.358,0,0,-2,0.8
ENSMUSG00000036151,TM6SF2,transmembrane 6 superfamily member 2,membrane|integral component of membrane|,None,None,10,0.7,0.539,10,-0.8,4.12,0.6,3.63,3.63,0.36,0,0,-1.4,1.7
ENSMUSG00000026662,SEPHS1,selenophosphate synthetase 1,nucleus|cytoplasm|plasma membrane|membrane|nuclear membrane|,biological_process|phosphorylation|,"nucleotide binding|catalytic activity|selenide, water dikinase activity|ATP binding|kinase activity|transferase activity|protein homodimerization activity|protein heterodimerization activity|",10,-0.5,3.71,10,0.2,0.958,-0.5,3.63,-3.63,0.36,0,0,-1.6,0.7
ENSMUSG00000055723,RRAS2,related RAS viral (r-ras) oncogene homolog 2,intracellular|plasma membrane|membrane|extracellular vesicular exosome|,osteoblast differentiation|GTP catabolic process|signal transduction|small GTPase mediated signal transduction|Ras protein signal transduction|cellular process|cellular process|positive regulation of cell migration|,nucleotide binding|protein binding|GTP binding|,10,0.4,2.81,10,0.2,1.26,0.3,3.61,3.61,0.361,0,0,-1,1.4
ENSMUSG00000025925,TERF1,telomeric repeat binding factor 1,"chromosome, telomeric region|nuclear telomere cap complex|nuclear telomere cap complex|nuclear chromosome, telomeric region|nucleus|nucleus|chromosome|nucleolus|cytoplasm|spindle|cytoskeleton|",telomere maintenance|age-dependent telomere shortening|activation of cysteine-type endopeptidase activity involved in apoptotic process|telomere maintenance via telomerase|cell cycle|mitotic nuclear division|mitotic spindle assembly checkpoint|negative regulation of DNA replication|telomere maintenance via telomere shortening|positive regulation of microtubule polymerization|negative regulation of telomere maintenance via telomerase|positive regulation of apoptotic process|positive regulation of mitosis|positive regulation of mitotic cell cycle|protein homooligomerization|cell division|negative regulation of telomerase activity|,"DNA binding|chromatin binding|double-stranded telomeric DNA binding|protein binding|microtubule binding|DNA binding, bending|telomeric DNA binding|telomeric DNA binding|protein homodimerization activity|protein heterodimerization activity|",10,0.4,5.86,10,-0.3,1.46,0.3,3.61,3.61,0.361,0,0,-0.6,1.4
ENSMUSG00000061665,CD2AP,CD2-associated protein,ruffle|cytoplasm|cytoskeleton|plasma membrane|cell-cell junction|cell cortex|endocytic vesicle|cell leading edge|filamentous actin|cell projection|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,cell cycle|mitotic nuclear division|vesicle organization|single organismal cell-cell adhesion|cell migration|negative regulation of transforming growth factor beta1 production|proteasome-mediated ubiquitin-dependent protein catabolic process|regulation of receptor-mediated endocytosis|cell division|positive regulation of protein localization to nucleus|regulation of actin cytoskeleton reorganization|,vascular endothelial growth factor receptor binding|protein binding|beta-catenin binding|protein C-terminus binding|SH3 domain binding|protein complex binding|cadherin binding|,10,-0.9,3.58,10,-0.3,1.86,-0.5,3.61,-3.61,0.361,0,0,-1.8,0
ENSMUSG00000036777,ANLN,"anillin, actin binding protein",nucleus|cytoplasm|actomyosin contractile ring|cytoskeleton|actin cytoskeleton|intracellular membrane-bounded organelle|,mitotic cytokinesis|hematopoietic progenitor cell differentiation|cell cycle|mitotic nuclear division|cell division|,actin binding|,10,0.7,5.69,10,0.1,0.657,0.6,3.6,3.6,0.362,0,0,-0.1,1.8
ENSMUSG00000029003,MAD2L2,MAD2 mitotic arrest deficient-like 2,nucleus|anaphase-promoting complex|cytoplasm|spindle|cytoskeleton|zeta DNA polymerase complex|,"negative regulation of transcription from RNA polymerase II promoter|regulation of cell growth|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|actin filament organization|cell cycle|mitotic nuclear division|negative regulation of epithelial to mesenchymal transition|negative regulation of transcription by competitive promoter binding|positive regulation of peptidyl-serine phosphorylation|negative regulation of protein catabolic process|DNA damage response, signal transduction resulting in transcription|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription, DNA-templated|cell division|negative regulation of mitotic anaphase-promoting complex activity|negative regulation of canonical Wnt signaling pathway|negative regulation of cell-cell adhesion mediated by cadherin|negative regulation of transcription regulatory region DNA binding|",RNA polymerase II activating transcription factor binding|JUN kinase binding|,9,0.3,2.93,9,0.8,1.5,0.4,3.6,3.6,0.362,0,0,-0.3,1.6
ENSMUSG00000005087,CD44,CD44 antigen,nucleus|cytoplasm|Golgi apparatus|plasma membrane|plasma membrane|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|protein complex|extracellular vesicular exosome|,"regulation of cell growth|branching involved in ureteric bud morphogenesis|wound healing involved in inflammatory response|positive regulation of adaptive immune response|negative regulation of mature B cell apoptotic process|cell adhesion|cell adhesion|positive regulation of gene expression|Wnt signaling pathway|cell migration|hyaluronan catabolic process|neuron projection development|positive regulation of neutrophil apoptotic process|positive regulation of peptidyl-serine phosphorylation|positive regulation of peptidyl-serine phosphorylation|positive regulation of heterotypic cell-cell adhesion|macrophage fusion|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of DNA damage response, signal transduction by p53 class mediator|cellular response to fibroblast growth factor stimulus|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|branching involved in prostate gland morphogenesis|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|monocyte aggregation|positive regulation of monocyte aggregation|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|",hyalurononglucosaminidase activity|transmembrane signaling receptor activity|transmembrane signaling receptor activity|epidermal growth factor receptor binding|protein binding|hyaluronic acid binding|hyaluronic acid binding|hyaluronic acid binding|protein kinase binding|cytokine binding|phosphoprotein binding|,10,0.3,2.28,10,0.2,1.64,0.2,3.6,3.6,0.362,0,0,-0.6,1.2
ENSMUSG00000024979,TECTB,tectorin beta,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|plasma membrane|membrane|anchored component of membrane|,sensory perception of sound|,extracellular matrix structural constituent|extracellular matrix structural constituent|,10,-0.7,4.81,10,-0.2,0.937,-0.6,3.58,-3.58,0.364,0,0,-1.6,1.4
ENSMUSG00000045967,GPR158,G protein-coupled receptor 158,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|protein localization to plasma membrane|,signal transducer activity|G-protein coupled receptor activity|protein binding|,10,0.2,0.286,10,-1.2,6.51,-1.2,3.57,-3.57,0.364,0,0,-2,0
ENSMUSG00000037138,AFF3,"AF4/FMR2 family, member 3",nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|response to tumor necrosis factor|embryonic hindlimb morphogenesis|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|,9,-0.4,1.26,9,-0.3,2.58,-0.3,3.52,-3.52,0.367,0,0,-1.4,0.8
ENSMUSG00000030314,ATG7,autophagy related 7,pre-autophagosomal structure|cytoplasm|cytosol|axoneme|,mitochondrion degradation|liver development|protein lipidation|C-terminal protein lipidation|cellular amino acid metabolic process|transport|autophagy|cellular response to nitrogen starvation|organelle organization|mitochondrion organization|adult walking behavior|cellular response to starvation|post-embryonic development|positive regulation of autophagy|protein transport|macroautophagy|positive regulation of macroautophagy|protein ubiquitination|cerebellar Purkinje cell layer development|pyramidal neuron development|central nervous system neuron axonogenesis|cerebral cortex development|protein catabolic process|neuron projection development|regulation of protein ubiquitination|positive regulation of protein modification process|positive regulation of protein modification process|protein modification by small protein conjugation|piecemeal microautophagy of nucleus|negative stranded viral RNA replication|response to starvation|positive regulation of apoptotic process|negative regulation of apoptotic process|late nucleophagy|positive regulation of protein catabolic process|neurological system process|cardiac muscle cell development|membrane organization|positive regulation of mucus secretion|cellular response to hyperoxia|,catalytic activity|ubiquitin activating enzyme activity|protein binding|transcription factor binding|Atg12 activating enzyme activity|Atg8 activating enzyme|protein homodimerization activity|,10,0.1,0.424,10,-0.5,6.06,-0.4,3.5,-3.5,0.369,0,0,-1.4,0.4
ENSMUSG00000029217,TEC,tec protein tyrosine kinase,cytoplasm|cytoskeleton|plasma membrane|cell-cell junction|membrane|,immune system process|protein phosphorylation|integrin-mediated signaling pathway|regulation of platelet activation|phosphorylation|peptidyl-tyrosine phosphorylation|intracellular signal transduction|B cell receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.5,1.75,10,0.3,2.3,0.4,3.49,3.49,0.37,0,0,-0.6,1.5
ENSMUSG00000089929,BCL2A1B,B cell leukemia/lymphoma 2 related protein A1b,mitochondrial outer membrane|,intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of apoptotic process|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of intrinsic apoptotic signaling pathway|,protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|BH domain binding|,7,-0.2,0.674,7,0.6,4.8,0.5,3.47,3.47,0.371,0,0,-0.6,1.8
ENSMUSG00000024151,MSH2,mutS homolog 2 (E. coli),nuclear chromosome|intracellular|nucleus|nucleus|nucleus|membrane|MutSalpha complex|MutSalpha complex|MutSbeta complex|MutSbeta complex|,meiotic mismatch repair|in utero embryonic development|somatic recombination of immunoglobulin genes involved in immune response|oxidative phosphorylation|ATP catabolic process|ATP catabolic process|DNA repair|DNA repair|mismatch repair|mismatch repair|mismatch repair|mismatch repair|postreplication repair|postreplication repair|double-strand break repair|meiotic gene conversion|cellular response to DNA damage stimulus|cell cycle|cell cycle arrest|germ cell development|determination of adult lifespan|male gonad development|intrinsic apoptotic signaling pathway in response to DNA damage|response to X-ray|response to UV-B|somatic hypermutation of immunoglobulin genes|somatic hypermutation of immunoglobulin genes|somatic recombination of immunoglobulin gene segments|somatic recombination of immunoglobulin gene segments|B cell mediated immunity|B cell differentiation|intra-S DNA damage checkpoint|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of neuron apoptotic process|maintenance of DNA repeat elements|maintenance of DNA repeat elements|negative regulation of reciprocal meiotic recombination|isotype switching|negative regulation of DNA recombination|negative regulation of DNA recombination|positive regulation of helicase activity|,nucleotide binding|magnesium ion binding|four-way junction DNA binding|four-way junction DNA binding|Y-form DNA binding|heteroduplex DNA loop binding|double-strand/single-strand DNA junction binding|DNA binding|DNA binding|damaged DNA binding|double-stranded DNA binding|single-stranded DNA binding|ATP binding|protein C-terminus binding|DNA-dependent ATPase activity|ATPase activity|ATPase activity|centromeric DNA binding|enzyme binding|protein kinase binding|mismatched DNA binding|mismatched DNA binding|guanine/thymine mispair binding|guanine/thymine mispair binding|guanine/thymine mispair binding|single base insertion or deletion binding|dinucleotide insertion or deletion binding|single guanine insertion binding|single thymine insertion binding|dinucleotide repeat insertion binding|oxidized purine DNA binding|MutLalpha complex binding|protein homodimerization activity|ADP binding|,10,0.1,0.285,10,0.5,4.61,0.4,3.42,3.42,0.375,0,0,-0.1,1.6
ENSMUSG00000028896,RCC1,regulator of chromosome condensation 1,nuclear chromatin|condensed nuclear chromosome|nucleus|cytoplasm|nuclear membrane|,G1/S transition of mitotic cell cycle|cell cycle|mitotic spindle organization|chromosome segregation|mitotic nuclear division|regulation of mitosis|positive regulation of Ran GTPase activity|positive regulation of Ran GTPase activity|spindle assembly|cell division|,DNA binding|chromatin binding|guanyl-nucleotide exchange factor activity|Ran guanyl-nucleotide exchange factor activity|Ran guanyl-nucleotide exchange factor activity|nucleosomal DNA binding|histone binding|,10,0.4,3.72,10,-0.9,3.79,0.3,3.42,3.42,0.375,0,0,-1.8,1
ENSMUSG00000095607,TRAV5-4,T cell receptor alpha variable 5-4,None,None,None,10,0.2,1.56,10,0.3,2.09,0.3,3.41,3.41,0.375,0,0,-1.3,1
ENSMUSG00000035242,OAZ1,ornithine decarboxylase antizyme 1,None,polyamine metabolic process|negative regulation of catalytic activity|negative regulation of catalytic activity|positive regulation of protein catabolic process|,enzyme inhibitor activity|protein binding|ornithine decarboxylase inhibitor activity|ornithine decarboxylase inhibitor activity|ornithine decarboxylase inhibitor activity|enzyme binding|protein heterodimerization activity|,10,0.3,3.22,10,-0.3,0.472,0.3,3.4,3.4,0.376,0,0,-0.7,1.3
ENSMUSG00000031370,ZRSR2,"zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2",nucleus|spliceosomal complex|U12-type spliceosomal complex|nucleolus|ribonucleoprotein complex|,"spliceosomal complex assembly|mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|pre-mRNA 3'-splice site binding|metal ion binding|,10,0.3,0.617,10,-1.2,6.76,-1.2,3.4,-3.4,0.376,0,0,-2,0.2
ENSMUSG00000028965,TNFRSF9,"tumor necrosis factor receptor superfamily, member 9",extracellular space|external side of plasma membrane|membrane|integral component of membrane|,regulation of cell proliferation|protein homotrimerization|negative regulation of interleukin-10 secretion|negative regulation of interleukin-12 secretion|,receptor activity|cytokine binding|,10,0.3,2.44,10,0.5,1.25,0.4,3.38,3.38,0.377,0,0,-0.4,1.3
ENSMUSG00000025558,DOCK9,dedicator of cytokinesis 9,membrane|membrane|,small GTPase mediated signal transduction|positive regulation of Rho GTPase activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho GTPase binding|,10,0.4,5.86,10,-0.1,0.486,0.4,3.38,3.38,0.377,0,0,-0.7,1.5
ENSMUSG00000024050,WIZ,widely-interspaced zinc finger motifs,nucleus|nucleus|extracellular vesicular exosome|,positive regulation of nuclear cell cycle DNA replication|protein stabilization|protein stabilization|protein heterotrimerization|protein heterotrimerization|,protein binding|metal ion binding|SET domain binding|,10,0.2,0.455,10,0.3,3.38,0.3,3.38,3.38,0.377,0,0,-0.7,1.5
ENSMUSG00000003974,GRM3,"glutamate receptor, metabotropic 3",plasma membrane|integral component of plasma membrane|postsynaptic density|membrane|integral component of membrane|axon|presynaptic membrane|neuron projection|dendritic spine|postsynaptic membrane|presynaptic active zone|astrocyte projection|,"signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|sensory perception of pain|synaptic transmission, glutamatergic|regulation of synaptic transmission|regulation of sensory perception of pain|regulation of synaptic transmission, glutamatergic|",group II metabotropic glutamate receptor activity|group II metabotropic glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|calcium channel regulator activity|,10,-0.5,0.0653,10,-0.4,3.51,-0.4,3.36,-3.36,0.379,0,0,-1.4,0.3
ENSMUSG00000022996,WNT10B,"wingless-type MMTV integration site family, member 10B",extracellular region|proteinaceous extracellular matrix|extracellular space|,G2/M transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|lipid metabolic process|cell cycle arrest|signal transduction|smoothened signaling pathway|cell-cell signaling|multicellular organismal development|positive regulation of cell proliferation|organ morphogenesis|positive regulation of G2/M transition of mitotic cell cycle|myoblast differentiation involved in skeletal muscle regeneration|Wnt signaling pathway|Wnt signaling pathway|neuron differentiation|positive regulation of bone mineralization|positive regulation of epithelial cell differentiation|regulation of proteasomal ubiquitin-dependent protein catabolic process|regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of apoptotic process|skeletal muscle tissue regeneration|cell fate commitment|regulation of fat cell differentiation|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|positive regulation of osteoblast differentiation|positive regulation of ossification|positive regulation of ossification|positive regulation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of skeletal muscle tissue development|skeletal muscle fiber development|negative regulation of epithelial cell proliferation|protein stabilization|sensory perception of taste|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of protein metabolic process|positive regulation of anagen|canonical Wnt signaling pathway|canonical Wnt signaling pathway|bone trabecula formation|fungiform papilla development|cellular response to organic substance|cellular response to cAMP|cellular response to parathyroid hormone stimulus|cellular response to organic cyclic compound|hematopoietic stem cell proliferation|hematopoietic stem cell proliferation|positive regulation of canonical Wnt signaling pathway|,receptor binding|frizzled binding|,10,0.4,2.77,10,0.7,1.12,0.4,3.35,3.35,0.379,0,0,-0.3,1.6
ENSMUSG00000006715,GMNN,geminin,nucleus|cytoplasm|,"regulation of DNA replication|protein complex assembly|cell cycle|negative regulation of DNA replication|organ morphogenesis|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|",transcription corepressor activity|protein binding|histone deacetylase binding|repressing transcription factor binding|,10,-0.5,3.47,10,0.5,1.25,-0.3,3.35,-3.35,0.379,0,0,-1.3,1.3
ENSMUSG00000037446,TULP1,tubby like protein 1,photoreceptor outer segment|photoreceptor inner segment|extracellular region|cytoplasm|plasma membrane|membrane|cell junction|cell projection|synapse|,retina homeostasis|phagocytosis|G-protein coupled receptor signaling pathway|visual perception|phototransduction|detection of visible light|dendrite development|eye photoreceptor cell development|photoreceptor cell maintenance|positive regulation of phagocytosis|response to stimulus|detection of light stimulus involved in visual perception|retina development in camera-type eye|,"protein binding|phosphatidylinositol-4,5-bisphosphate binding|G-protein coupled photoreceptor activity|actin filament binding|",10,0.5,5.14,10,0,0,0.4,3.27,3.27,0.385,0,0,-0.3,1.6
ENSMUSG00000020687,CDC27,cell division cycle 27,nucleus|anaphase-promoting complex|cytoplasm|centrosome|spindle microtubule|,cell cycle|metaphase/anaphase transition of mitotic cell cycle|cell division|protein K11-linked ubiquitination|,protein phosphatase binding|,9,-1,3.35,10,1.1,5.48,1.1,3.27,3.27,0.385,0,0,-1.3,2
ENSMUSG00000052372,IL1RAPL1,interleukin 1 receptor accessory protein-like 1,cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|dendrite|cell projection|postsynaptic membrane|,heterophilic cell-cell adhesion|signal transduction|regulation of neuron projection development|neuron differentiation|regulation of ion transmembrane transport|negative regulation of exocytosis|positive regulation of dendrite morphogenesis|calcium ion transmembrane transport|presynaptic membrane assembly|,receptor binding|voltage-gated calcium channel activity|protein binding|,10,0.3,0.243,10,0.9,3.93,0.7,3.26,3.26,0.386,0,0,-0.1,1.8
ENSMUSG00000005886,NCOA2,nuclear receptor coactivator 2,nucleus|nucleus|cytoplasm|rough endoplasmic reticulum|Golgi apparatus|microtubule|postsynaptic density|dendrite|neuronal cell body|dendritic spine|presynaptic active zone|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|regulation of glucose metabolic process|negative regulation of transcription, DNA-templated|positive regulation of female receptivity|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of receptor activity|positive regulation of glucocorticoid receptor signaling pathway|",DNA binding|chromatin binding|transcription coactivator activity|transcription coactivator activity|histone acetyltransferase activity|signal transducer activity|receptor binding|protein binding|transcription factor binding|ligand-dependent nuclear receptor binding|PDZ domain binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity|thyroid hormone receptor coactivator activity|protein complex binding|progesterone receptor binding|nuclear hormone receptor binding|glucocorticoid receptor binding|retinoic acid receptor binding|retinoid X receptor binding|thyroid hormone receptor binding|protein dimerization activity|DNA polymerase binding|,10,0.3,3.11,10,0.1,0.87,0.2,3.26,3.26,0.386,0,0,-0.3,1.4
ENSMUSG00000059173,PDE1A,"phosphodiesterase 1A, calmodulin-dependent",nucleus|cytoplasm|neuronal cell body|,cAMP catabolic process|signal transduction|regulation of smooth muscle cell apoptotic process|cGMP catabolic process|regulation of smooth muscle cell proliferation|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|calmodulin binding|phosphoric diester hydrolase activity|hydrolase activity|cGMP binding|metal ion binding|calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity|",10,0.2,1.07,10,0.2,2.37,0.2,3.22,3.22,0.389,0,0,-1.8,0.9
ENSMUSG00000019470,XAB2,XPA binding protein 2,intracellular|nucleus|spliceosomal complex|membrane|catalytic step 2 spliceosome|,"blastocyst development|DNA repair|transcription-coupled nucleotide-excision repair|transcription, DNA-templated|RNA processing|mRNA processing|cellular response to DNA damage stimulus|RNA splicing|",molecular_function|,10,-0.6,6.06,10,0.3,0.867,-0.6,3.21,-3.21,0.39,0,0,-1.7,0.7
ENSMUSG00000048109,RBM15,RNA binding motif protein 15,nucleus|nucleus|,negative regulation of transcription from RNA polymerase II promoter|patterning of blood vessels|positive regulation of transcription of Notch receptor target|negative regulation of myeloid cell differentiation|negative regulation of myeloid cell differentiation|spleen development|ventricular septum morphogenesis|placenta blood vessel development|,protein binding|poly(A) RNA binding|,10,-0.4,0.862,10,-0.6,2.88,-0.5,3.16,-3.16,0.394,0,0,-1.6,0.2
ENSMUSG00000027552,E2F5,E2F transcription factor 5,nucleus|nucleus|nuclear envelope|transcription factor complex|cytoplasm|sarcoplasm|,"G1/S transition of mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|organ morphogenesis|regulation of cell cycle|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|,10,0.3,3.8,10,0,0,0.3,3.09,3.09,0.399,0,0,-1.1,1.2
ENSMUSG00000040205,CUZD1,CUB and zona pellucida-like domains 1,membrane|integral component of membrane|integral component of membrane|cytoplasmic vesicle|zymogen granule|zymogen granule membrane|,cell cycle|cell adhesion|female pregnancy|hormone-mediated signaling pathway|trypsinogen activation|cell division|,None,10,0.1,0.343,10,-0.6,4.96,-0.3,3.09,-3.09,0.399,0,0,-1.6,0.4
ENSMUSG00000032293,IREB2,iron responsive element binding protein 2,cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|cytosol|,regulation of translation|protoporphyrinogen IX biosynthetic process|cellular iron ion homeostasis|cellular iron ion homeostasis|cellular iron ion homeostasis|metabolic process|post-embryonic development|regulation of gene expression|negative regulation of translation|erythrocyte homeostasis|intestinal absorption|,"RNA binding|iron-responsive element binding|iron-responsive element binding|translation repressor activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0,0,10,0.3,4.16,0.3,3.09,3.09,0.399,0,0,-0.9,1.3
ENSMUSG00000019979,APAF1,apoptotic peptidase activating factor 1,nucleus|cytoplasm|cytosol|cytosol|apoptosome|apoptosome|extracellular vesicular exosome|,neural tube closure|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|defense response|multicellular organismal development|brain development|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|cardiac muscle cell apoptotic process|forebrain development|regulation of apoptotic process|protein homooligomerization|neuron apoptotic process|cellular response to transforming growth factor beta stimulus|regulation of apoptotic DNA fragmentation|positive regulation of apoptotic signaling pathway|,nucleotide binding|ATP binding|cysteine-type endopeptidase activator activity involved in apoptotic process|heat shock protein binding|identical protein binding|identical protein binding|ADP binding|,10,0,0,10,-0.4,4.15,-0.3,3.08,-3.08,0.4,0,0,-1.3,1.3
ENSMUSG00000022681,NTAN1,N-terminal Asn amidase,nucleus|cytoplasm|,memory|adult locomotory behavior|,"histone deacetylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|",10,0.4,0.74,10,0.4,2.53,0.4,3.08,3.08,0.4,0,0,-0.3,1.7
ENSMUSG00000034098,FSTL5,follistatin-like 5,extracellular region|,biological_process|,calcium ion binding|metal ion binding|,10,0.4,0.47,10,-0.7,3.88,-0.3,3.06,-3.06,0.401,0,0,-1.7,0.7
ENSMUSG00000020053,IGF1,insulin-like growth factor 1,extracellular region|interstitial matrix|extracellular space|extracellular space|intracellular|neuronal cell body|,"cell activation|regulation of protein phosphorylation|blood vessel remodeling|blood vessel remodeling|regulation of translation|nervous system development|memory|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|glial cell differentiation|positive regulation of cardiac muscle hypertrophy|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of phosphatidylinositol 3-kinase signaling|skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration|muscle hypertrophy|myotube cell development|positive regulation of smooth muscle cell migration|positive regulation of cerebellar granule cell precursor proliferation|water homeostasis|proteoglycan biosynthetic process|positive regulation of cell growth|lung development|mammary gland development|exocrine pancreas development|regulation of establishment or maintenance of cell polarity|regulation of intracellular steroid hormone receptor signaling pathway|positive regulation of protein import into nucleus, translocation|negative regulation of smooth muscle cell apoptotic process|multicellular organism growth|bone mineralization involved in bone maturation|positive regulation of activated T cell proliferation|regulation of cell proliferation|positive regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of DNA binding|positive regulation of MAPK cascade|positive regulation of insulin-like growth factor receptor signaling pathway|myoblast differentiation|positive regulation of fat cell differentiation|positive regulation of osteoblast differentiation|positive regulation of glycogen biosynthetic process|positive regulation of DNA replication|positive regulation of glycolytic process|positive regulation of mitosis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of glucose import|positive regulation of Ras protein signal transduction|insulin-like growth factor receptor signaling pathway|insulin-like growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of fibroblast proliferation|lung alveolus development|lung alveolus development|cell development|positive regulation of smooth muscle cell proliferation|branching morphogenesis of an epithelial tube|inner ear development|chondroitin sulfate proteoglycan biosynthetic process|positive regulation of epithelial cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|detection of mechanical stimulus involved in sensory perception|regulation of protein metabolic process|myoblast proliferation|positive regulation of protein kinase B signaling|regulation of calcium ion transport|lung vasculature development|lung vasculature development|lung lobe morphogenesis|lung lobe morphogenesis|Type I pneumocyte differentiation|Type II pneumocyte differentiation|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis|prostate gland growth|prostate gland growth|prostate gland epithelium morphogenesis|prostate gland stromal morphogenesis|negative regulation of androgen receptor signaling pathway|negative regulation of ERK1 and ERK2 cascade|positive regulation of calcineurin-NFAT signaling cascade|positive regulation of protein serine/threonine kinase activity|positive regulation of steroid hormone biosynthetic process|negative regulation of release of cytochrome c from mitochondria|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of neuron death|positive regulation of myoblast proliferation|negative regulation of extrinsic apoptotic signaling pathway|",insulin receptor binding|insulin-like growth factor receptor binding|insulin-like growth factor receptor binding|integrin binding|hormone activity|steroid binding|protein binding|growth factor activity|protein serine/threonine kinase activator activity|,10,0.6,5.81,10,0,0,0.5,3.06,3.06,0.401,0,0,-0.2,1.8
ENSMUSG00000028252,CCNC,cyclin C,"nucleus|DNA-directed RNA polymerase II, holoenzyme|mediator complex|","regulation of cyclin-dependent protein serine/threonine kinase activity|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of cell cycle|",protein kinase binding|,10,0.4,3.71,10,0.1,0.355,0.3,3.05,3.05,0.402,0,0,-0.3,1.6
ENSMUSG00000070002,ELL,elongation factor RNA polymerase II,nucleus|transcription elongation factor complex|nuclear speck|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription elongation from RNA polymerase II promoter|negative regulation of phosphatase activity|",phosphatase binding|,10,0.3,1.79,10,0.5,1.74,0.3,3.05,3.05,0.402,0,0,-0.6,1.5
ENSMUSG00000034252,SENP6,SUMO/sentrin specific peptidase 6,nucleus|cytoplasm|,proteolysis|protein desumoylation|protein modification by small protein removal|regulation of spindle assembly|regulation of kinetochore assembly|,nucleic acid binding|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|SUMO-specific protease activity|,10,0.1,0.616,10,0.5,2.98,0.2,3.05,3.05,0.402,0,0,-0.7,1.4
ENSMUSG00000025912,MYBL1,myeloblastosis oncogene-like 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|,10,0.1,0.135,10,0.5,4.38,0.5,3.04,3.04,0.403,0,0,-0.5,1.8
ENSMUSG00000032812,ARAP1,"ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1",intracellular|cytoplasm|Golgi apparatus|trans-Golgi network|plasma membrane|membrane|cytoplasmic vesicle|,positive regulation of receptor recycling|signal transduction|regulation of cell shape|regulation of ARF GTPase activity|positive regulation of Cdc42 GTPase activity|regulation of cellular component movement|positive regulation of filopodium assembly|negative regulation of stress fiber assembly|,"GTPase activator activity|Rho GTPase activator activity|phosphatidylinositol-3,4,5-trisphosphate binding|ARF GTPase activator activity|zinc ion binding|type 1 angiotensin receptor binding|metal ion binding|",10,0.2,1.63,10,0.3,1.65,0.3,3.04,3.04,0.403,0,0,-0.7,1.3
ENSMUSG00000021068,NIN,ninein,spindle pole|cell|nucleolus|cytoplasm|centrosome|centrosome|centriole|cytoskeleton|microtubule|,microtubule anchoring at centrosome|centrosome-templated microtubule nucleation|,nucleotide binding|calcium ion binding|protein binding|GTP binding|kinase binding|,10,0.1,0.0468,10,0.3,3.88,0.3,3.04,3.04,0.403,0,0,-0.7,1.4
ENSMUSG00000064109,HCST,hematopoietic cell signal transducer,cell surface|membrane|integral component of membrane|,positive regulation of phosphatidylinositol 3-kinase signaling|,receptor binding|protein binding|phosphatidylinositol 3-kinase binding|,10,0.3,2.96,10,0.1,0.592,0.2,3.04,3.04,0.403,0,0,-0.5,1.4
ENSMUSG00000003282,PLAG1,pleiomorphic adenoma gene 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of gene expression|negative regulation of gene expression|gland morphogenesis|multicellular organism growth|organ growth|positive regulation of transcription from RNA polymerase II promoter|positive regulation of glial cell proliferation|prostate gland growth|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.3,1.79,10,-0.2,1.47,-0.2,3.02,-3.02,0.404,0,0,-1.3,0.5
ENSMUSG00000023940,SGOL1,shugoshin-like 1 (S. pombe),"chromosome, centromeric region|chromosome, centromeric region|kinetochore|kinetochore|kinetochore|condensed chromosome, centromeric region|condensed nuclear chromosome, centromeric region|spindle pole|nucleus|chromosome|cytoplasm|centrosome|cytoskeleton|mitotic cohesin complex|",cell cycle|chromosome segregation|mitotic nuclear division|attachment of spindle microtubules to kinetochore|centriole-centriole cohesion|centriole-centriole cohesion|meiotic chromosome segregation|cell division|,kinase binding|,10,2.2,6.62,10,-0.6,1.75,2.1,3.02,3.02,0.404,0,0,-0.8,4
ENSMUSG00000006344,GGT5,gamma-glutamyltransferase 5,plasma membrane|membrane|integral component of membrane|,proteolysis|glutathione metabolic process|glutathione biosynthetic process|inflammatory response|leukotriene biosynthetic process|,"gamma-glutamyltransferase activity|gamma-glutamyltransferase activity|peptidase activity|transferase activity|transferase activity, transferring acyl groups|hydrolase activity|glutathione hydrolase activity|",10,-0.9,5.26,10,0,0,-0.8,3.01,-3.01,0.405,0,0,-2,0.1
ENSMUSG00000028186,UOX,urate oxidase,mitochondrion|peroxisome|peroxisome|,purine nucleobase metabolic process|oxidation-reduction process|,urate oxidase activity|oxidoreductase activity|,10,-0.2,0.404,10,-1,5.32,-0.9,3.01,-3.01,0.405,0,0,-2,0
ENSMUSG00000033813,TCEA1,transcription elongation factor A (SII) 1,nucleus|nucleoplasm|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|erythrocyte differentiation|regulation of DNA-templated transcription, elongation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|protein binding|zinc ion binding|metal ion binding|,10,-0.4,0.68,10,1.1,5,0.3,3.01,3.01,0.405,0,0,-0.4,2
ENSMUSG00000038729,AKAP2,A kinase (PRKA) anchor protein 2,protein complex|,actin filament organization|transmembrane receptor protein serine/threonine kinase signaling pathway|protein localization|protein heterooligomerization|,protein domain specific binding|protein kinase A binding|,10,1.3,6.22,10,-0.6,3.67,1.2,3.01,3.01,0.405,0,0,-0.9,2
ENSMUSG00000039745,HTATIP2,"HIV-1 tat interactive protein 2, homolog (human)",nucleus|nuclear envelope|nuclear envelope|cytoplasm|cytoplasm|membrane|,angiogenesis|apoptotic process|multicellular organismal development|cell differentiation|positive regulation of programmed cell death|regulation of angiogenesis|regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter during mitosis|protein autophosphorylation|nuclear import|nuclear import|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|protein serine/threonine kinase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.9,1.95,10,0.4,1.77,0.7,2.98,2.98,0.408,0,0,-0.3,1.9
ENSMUSG00000021367,EDN1,endothelin 1,extracellular region|extracellular space|extracellular space|cytoplasm|Weibel-Palade body|basal part of cell|rough endoplasmic reticulum lumen|,negative regulation of transcription from RNA polymerase II promoter|skeletal system development|prostaglandin biosynthetic process|patterning of blood vessels|response to hypoxia|in utero embryonic development|histamine secretion|regulation of systemic arterial blood pressure by endothelin|regulation of pH|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|protein kinase C-activating G-protein coupled receptor signaling pathway|cell-cell signaling|heart development|respiratory gaseous exchange|body fluid secretion|regulation of blood pressure|regulation of blood pressure|positive regulation of cell proliferation|positive regulation of cell proliferation|dorsal/ventral pattern formation|positive regulation of heart rate|positive regulation of cardiac muscle hypertrophy|positive regulation of receptor biosynthetic process|neural crest cell development|phosphatidylinositol 3-kinase signaling|artery smooth muscle contraction|vein smooth muscle contraction|glucose transport|cell growth|regulation of vasoconstriction|sensory perception of pain|calcium-mediated signaling|peptide hormone secretion|nitric oxide transport|positive regulation of cell migration|negative regulation of cAMP biosynthetic process|negative regulation of cAMP biosynthetic process|phospholipase D-activating G-protein coupled receptor signaling pathway|negative regulation of cellular protein metabolic process|positive regulation of prostaglandin secretion|negative regulation of smooth muscle cell apoptotic process|intracellular signal transduction|positive regulation of urine volume|positive regulation of urine volume|positive regulation of renal sodium excretion|epithelial fluid transport|vasoconstriction|protein kinase C deactivation|middle ear morphogenesis|positive regulation of odontogenesis|superoxide anion generation|rhythmic excitation|positive regulation of MAP kinase activity|positive regulation of JUN kinase activity|positive regulation of cell size|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle contraction|positive regulation of smooth muscle contraction|positive regulation of hormone secretion|negative regulation of hormone secretion|inositol phosphate-mediated signaling|blood vessel morphogenesis|positive regulation of smooth muscle cell proliferation|regulation of blood vessel size|cartilage development|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|negative regulation of nitric-oxide synthase biosynthetic process|membrane depolarization|regulation of sensory perception of pain|positive regulation of sarcomere organization|positive regulation of prostaglandin-endoperoxide synthase activity|positive regulation of neutrophil chemotaxis|,receptor binding|cytokine activity|hormone activity|protein binding|endothelin A receptor binding|endothelin A receptor binding|endothelin B receptor binding|,10,0.1,0.182,10,0.8,5.01,0.7,2.94,2.94,0.411,0,0,-0.3,1.8
ENSMUSG00000006134,CRKL,v-crk sarcoma virus CT10 oncogene homolog (avian)-like,cytoplasm|extracellular vesicular exosome|,blood vessel development|pattern specification process|heart development|organ morphogenesis|anterior/posterior pattern specification|thymus development|parathyroid gland development|,protein binding|poly(A) RNA binding|,10,0.3,1.97,10,1.1,3.44,0.3,2.92,2.92,0.413,0,0,-0.2,2
ENSMUSG00000028864,HGF,hepatocyte growth factor,extracellular space|membrane|,activation of MAPK activity|cell morphogenesis|liver development|proteolysis|cell proliferation|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of cell migration|positive regulation of myelination|cellular response to hepatocyte growth factor stimulus|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of angiogenesis|hepatocyte growth factor receptor signaling pathway|hepatocyte growth factor receptor signaling pathway|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|myoblast proliferation|cell chemotaxis|regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling|regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling|positive regulation of neuron projection regeneration|negative regulation of release of cytochrome c from mitochondria|negative regulation of hydrogen peroxide-mediated programmed cell death|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of DNA biosynthetic process|,catalytic activity|serine-type endopeptidase activity|growth factor activity|chemoattractant activity|identical protein binding|protein heterodimerization activity|,10,0.6,5.26,10,-0.1,0.145,0.6,2.91,2.91,0.414,0,0,-0.5,1.9
ENSMUSG00000020492,SKA2,spindle and kinetochore associated complex subunit 2,"chromosome, centromeric region|kinetochore|condensed chromosome outer kinetochore|chromosome|cytoplasm|cytoskeleton|microtubule|spindle microtubule|",mitotic anaphase|cell cycle|chromosome segregation|mitotic nuclear division|regulation of microtubule polymerization or depolymerization|cell division|,microtubule binding|,6,0.3,1.94,6,0.2,1.3,0.3,2.9,2.9,0.414,0,0,-0.9,1.8
ENSMUSG00000022863,BTG3,B cell translocation gene 3,cytoplasm|,negative regulation of mitotic cell cycle|,protein binding|,9,0,0,9,-0.5,4.39,-0.4,2.9,-2.9,0.414,0,0,-1.7,0.3
ENSMUSG00000052139,BRE,brain and reproductive organ-expressed protein,nuclear ubiquitin ligase complex|nucleus|cytoplasm|BRCA1-A complex|BRISC complex|,DNA repair|double-strand break repair|apoptotic process|cellular response to DNA damage stimulus|response to ionizing radiation|chromatin modification|G2 DNA damage checkpoint|positive regulation of DNA repair|,tumor necrosis factor receptor binding|tumor necrosis factor receptor binding|polyubiquitin binding|,10,0.3,1.75,10,0.3,1.34,0.3,2.89,2.89,0.415,0,0,-0.3,1.6
ENSMUSG00000019841,REV3L,"REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)",nucleus|chromosome|zeta DNA polymerase complex|zeta DNA polymerase complex|,nucleobase-containing compound metabolic process|DNA replication|DNA-dependent DNA replication|DNA repair|cellular response to DNA damage stimulus|translesion synthesis|,"nucleotide binding|nucleic acid binding|DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",9,0.2,0.832,8,0.4,2.44,0.3,2.87,2.87,0.417,0,0,-0.4,1.7
ENSMUSG00000024642,TLE4,"transducin-like enhancer of split 4, homolog of Drosophila E(spl)",nucleus|nucleus|neuron part|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|Wnt signaling pathway|negative regulation of transcription, DNA-templated|",chromatin binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription corepressor activity|transcription corepressor activity|protein binding|repressing transcription factor binding|,10,0,0,10,0.6,5.03,0.5,2.86,2.86,0.418,0,0,-0.2,1.7
ENSMUSG00000026098,PMS1,postmeiotic segregation increased 1 (S. cerevisiae),MutLalpha complex|,ATP catabolic process|mismatch repair|,single-stranded DNA binding|ATPase activity|,10,0.7,3.5,10,0,0,0.7,2.85,2.85,0.419,0,0,-0.4,1.9
ENSMUSG00000014767,TBP,TATA box binding protein,RNA polymerase I transcription factor complex|female pronucleus|male pronucleus|nucleus|nucleus|transcription factor TFIID complex|transcription factor TFIIA complex|nuclear euchromatin|cytoplasm|pronucleus|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase III promoter|transcription from RNA polymerase III promoter|positive regulation of transcription, DNA-templated|",RNA polymerase II repressing transcription factor binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|transcription regulatory region DNA binding|repressing transcription factor binding|,10,0.2,0.385,10,0.4,2.78,0.3,2.85,2.85,0.419,0,0,-0.7,1.5
ENSMUSG00000020932,GFAP,glial fibrillary acidic protein,cytoplasm|cytoplasm|intermediate filament|membrane|cell projection|cell body|astrocyte projection|,response to wounding|positive regulation of Schwann cell proliferation|negative regulation of neuron projection development|negative regulation of neuron projection development|astrocyte development|extracellular matrix organization|neuron projection regeneration|intermediate filament-based process|intermediate filament organization|intermediate filament organization|regulation of neurotransmitter uptake|Bergmann glial cell differentiation|positive regulation of glial cell proliferation|long-term synaptic potentiation|,integrin binding|structural molecule activity|structural constituent of cytoskeleton|protein binding|kinase binding|,10,0.5,3.36,10,0.1,0.403,0.5,2.83,2.83,0.42,0,0,-0.3,1.6
ENSMUSG00000073016,UPRT,uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae),nucleus|cytoplasm|,UMP biosynthetic process|,molecular_function|,10,0.6,5.31,10,-0.2,1.33,0.5,2.83,2.83,0.42,0,0,-0.5,1.7
ENSMUSG00000018476,KDM6B,KDM1 lysine (K)-specific demethylase 6B,nucleus|,inflammatory response|chromatin modification|histone demethylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|oxidation-reduction process|cellular response to hydrogen peroxide|histone H3-K27 demethylation|,"sulfonate dioxygenase activity|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|sequence-specific DNA binding|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|histone demethylase activity (H3-K27 specific)|",10,0.3,1.43,9,0.3,1.59,0.3,2.82,2.82,0.421,0,0,-1,1.6
ENSMUSG00000024429,GNL1,guanine nucleotide binding protein-like 1,nucleus|cytosol|,GTP catabolic process|cellular response to DNA damage stimulus|ribosome biogenesis|,nucleotide binding|GTPase activity|GTP binding|,10,0.1,0.258,10,0.4,3.68,0.4,2.81,2.81,0.422,0,0,-0.4,1.6
ENSMUSG00000091898,TNNC1,"troponin C, cardiac/slow skeletal",nucleus|mitochondrion|troponin complex|actin cytoskeleton|contractile fiber|,diaphragm contraction|regulation of muscle contraction|response to metal ion|regulation of muscle filament sliding speed|regulation of ATPase activity|ventricular cardiac muscle tissue morphogenesis|cardiac muscle contraction|,calcium ion binding|troponin I binding|troponin T binding|protein homodimerization activity|metal ion binding|calcium-dependent protein binding|actin filament binding|,10,-0.7,1.18,10,0.6,3.14,0.4,2.8,2.8,0.423,0,0,-1.3,1.6
ENSMUSG00000035045,ZC3H12B,zinc finger CCCH-type containing 12B,cellular_component|,biological_process|,molecular_function|,10,0.1,0.025,10,-0.3,3.92,-0.2,2.8,-2.8,0.423,0,0,-1.3,0.6
ENSMUSG00000026965,ANAPC2,anaphase promoting complex subunit 2,nucleus|anaphase-promoting complex|cullin-RING ubiquitin ligase complex|,ubiquitin-dependent protein catabolic process|cell cycle|mitotic nuclear division|nervous system development|cell differentiation|positive regulation of synaptic plasticity|positive regulation of axon extension|positive regulation of dendrite morphogenesis|cell division|protein K11-linked ubiquitination|positive regulation of synapse maturation|,ubiquitin protein ligase binding|,10,0.3,0.833,10,0.6,2.73,-0.6,2.79,-2.79,0.424,0,0,-1.5,1.3
ENSMUSG00000024909,EFEMP2,epidermal growth factor-containing fibulin-like extracellular matrix protein 2,extracellular region|proteinaceous extracellular matrix|membrane|extracellular vesicular exosome|,blood coagulation|,transmembrane signaling receptor activity|calcium ion binding|,10,0.2,0.748,10,0.3,2.34,0.3,2.79,2.79,0.424,0,0,-0.4,1.6
ENSMUSG00000021944,GATA4,GATA binding protein 4,nuclear chromatin|nucleus|nucleus|,"in utero embryonic development|gastrulation with mouth forming second|endoderm formation|heart looping|heart morphogenesis|outflow tract morphogenesis|atrioventricular valve morphogenesis|atrioventricular valve morphogenesis|atrioventricular valve formation|mitral valve formation|tricuspid valve formation|endocardial cushion development|endocardial cushion development|endocardial cushion development|cardiac right ventricle morphogenesis|ventricular cardiac muscle tissue development|cardiac septum development|ventricular septum development|atrial septum primum morphogenesis|atrial septum secundum morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell-cell signaling|spermatogenesis|heart development|male gonad development|response to mechanical stimulus|regulation of gene expression|regulation of gene expression|negative regulation of autophagy|positive regulation vascular endothelial growth factor production|cardiac muscle hypertrophy in response to stress|signal transduction involved in regulation of gene expression|BMP signaling pathway|positive regulation of BMP signaling pathway|response to retinoic acid|embryonic heart tube development|embryonic heart tube anterior/posterior pattern specification|tube morphogenesis|skeletal muscle cell differentiation|atrioventricular canal development|response to drug|response to estrogen|positive regulation of angiogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic digestive tract morphogenesis|embryonic morphogenesis|embryonic foregut morphogenesis|cardiac muscle tissue development|cardiac muscle cell differentiation|cardiac muscle cell differentiation|cardiac muscle cell differentiation|Sertoli cell differentiation|regulation of cardiac muscle cell proliferation|positive regulation of cardiac muscle cell proliferation|canonical Wnt signaling pathway|transdifferentiation|SMAD protein signal transduction|atrial septum morphogenesis|lung morphogenesis|lung lobe formation|diaphragm morphogenesis|intestinal epithelial cell differentiation|vasculogenesis involved in coronary vascular morphogenesis|cell growth involved in cardiac muscle cell development|cellular response to gonadotropin stimulus|cellular response to follicle-stimulating hormone stimulus|epithelial cell fate commitment|seminiferous tubule development|regulation of cardiac muscle cell contraction|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor binding transcription factor activity|RNA polymerase II transcription factor binding transcription factor activity|enhancer sequence-specific DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|transcription factor binding|zinc ion binding|activating transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|NFAT protein binding|co-SMAD binding|,10,0.3,3.68,10,0.1,0.0575,0.3,2.77,2.77,0.426,0,0,-0.4,1.6
ENSMUSG00000055435,MAF,avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|cytokine production|lens development in camera-type eye|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of gene expression|regulation of chondrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell development|inner ear development|lens fiber cell differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|sequence-specific DNA binding|protein heterodimerization activity|,10,0.3,1.54,10,0.2,1.73,0.2,2.75,2.75,0.428,0,0,-0.5,1.5
ENSMUSG00000050931,SGMS2,sphingomyelin synthase 2,Golgi apparatus|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|integral component of Golgi membrane|integral component of Golgi membrane|integral component of cell outer membrane|,lipid metabolic process|sphingolipid metabolic process|sphingomyelin biosynthetic process|sphingomyelin biosynthetic process|phosphorylation|,kinase activity|transferase activity|sphingomyelin synthase activity|ceramide cholinephosphotransferase activity|ceramide cholinephosphotransferase activity|,9,0.1,0.258,10,0.4,3.65,0.3,2.74,2.74,0.429,0,0,-0.3,1.5
ENSMUSG00000033306,LPP,LIM domain containing preferred translocation partner in lipoma,nucleus|cytoplasm|focal adhesion|cell junction|,cell adhesion|,protein binding|zinc ion binding|metal ion binding|,10,-0.5,4.52,10,-0.1,0.0227,-0.4,2.69,-2.69,0.433,0,0,-1.7,0.2
ENSMUSG00000037013,SS18,"synovial sarcoma translocation, Chromosome 18",nucleus|cytoplasmic microtubule|npBAF complex|,"microtubule cytoskeleton organization|cell morphogenesis|cell morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|cytoskeleton organization|intracellular signal transduction|response to drug|positive regulation of transcription from RNA polymerase II promoter|ephrin receptor signaling pathway|neuronal stem cell maintenance|",ligand-dependent nuclear receptor transcription coactivator activity|,10,0.3,0.688,10,0.4,2.4,0.3,2.67,2.67,0.435,0,0,-1.1,1.3
ENSMUSG00000049436,UPK1B,uroplakin 1B,membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,epithelial cell differentiation|,None,10,0,0,10,-0.4,4.32,-0.3,2.66,-2.66,0.436,0,0,-1.5,0.4
ENSMUSG00000058135,GSTM1,"glutathione S-transferase, mu 1",extracellular region|cytoplasm|protein complex|,glutathione metabolic process|metabolic process|cellular response to drug|,glutathione transferase activity|steroid binding|protein binding|nickel cation binding|transferase activity|protein homodimerization activity|protein homodimerization activity|protein heterodimerization activity|,10,1,2.86,10,0.2,1.84,0.2,2.66,2.66,0.436,0,0,-0.5,2
ENSMUSG00000032498,MLH1,mutL homolog 1 (E. coli),condensed chromosome|condensed chromosome|condensed nuclear chromosome|synaptonemal complex|synaptonemal complex|male germ cell nucleus|nucleus|chromosome|chiasma|membrane|mismatch repair complex|MutLalpha complex|,nuclear-transcribed mRNA poly(A) tail shortening|resolution of meiotic recombination intermediates|somatic recombination of immunoglobulin genes involved in immune response|ATP catabolic process|DNA repair|mismatch repair|mismatch repair|mismatch repair|double-strand break repair via nonhomologous end joining|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|cell cycle|male meiosis chromosome segregation|meiotic nuclear division|meiotic nuclear division|synapsis|reciprocal meiotic recombination|male meiosis|spermatogenesis|intrinsic apoptotic signaling pathway in response to DNA damage|somatic hypermutation of immunoglobulin genes|somatic recombination of immunoglobulin gene segments|meiotic metaphase I plate congression|meiotic chromosome segregation|isotype switching|negative regulation of mitotic recombination|oogenesis|spindle midzone assembly involved in meiosis|,single-stranded DNA binding|single-stranded DNA binding|ATP binding|ATPase activity|mismatched DNA binding|guanine/thymine mispair binding|guanine/thymine mispair binding|MutSalpha complex binding|structure-specific DNA binding|,10,0.4,4.33,10,-0.1,0.0303,0.3,2.65,2.65,0.437,0,0,-0.4,1.6
ENSMUSG00000069495,EPC2,enhancer of polycomb homolog 2 (Drosophila),cellular_component|nucleus|Piccolo NuA4 histone acetyltransferase complex|NuA4 histone acetyltransferase complex|,"DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|biological_process|chromatin modification|",molecular_function|,10,0.2,1.45,10,0.2,1.39,0.2,2.65,2.65,0.437,0,0,-0.5,1.5
ENSMUSG00000075249,FSIP2,fibrous sheath-interacting protein 2,mitochondrion|motile cilium|,biological_process|,protein binding|,10,0,0,10,0.6,4.96,0.5,2.65,2.65,0.437,0,0,-1.1,2
ENSMUSG00000009293,UBE2G2,ubiquitin-conjugating enzyme E2G 2,endoplasmic reticulum|cytosol|cytosol|,protein N-linked glycosylation via asparagine|ER-associated ubiquitin-dependent protein catabolic process|ER-associated ubiquitin-dependent protein catabolic process|protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|,8,0.3,1.38,8,0.9,2.63,0.5,2.61,2.61,0.441,0,0,-0.1,1.9
ENSMUSG00000021115,VRK1,vaccinia related kinase 1,nucleus|nucleus|cytoplasm|Golgi stack|cytoskeleton|,protein phosphorylation|protein phosphorylation|cell cycle|mitotic nuclear division|phosphorylation|histone H3-S10 phosphorylation|protein autophosphorylation|protein autophosphorylation|cell division|histone H3-T3 phosphorylation|Golgi disassembly|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|nucleosomal histone binding|histone kinase activity (H3-S10 specific)|histone kinase activity (H3-T3 specific)|",10,0.4,3.41,10,0,0,0.4,2.6,2.6,0.442,0,0,-0.3,1.8
ENSMUSG00000069919,HBA-A1,"hemoglobin alpha, adult chain 1",hemoglobin complex|membrane|cytosolic small ribosomal subunit|haptoglobin-hemoglobin complex|extracellular vesicular exosome|blood microparticle|,in utero embryonic development|erythrocyte development|,peroxidase activity|haptoglobin binding|,2,-0.2,0.369,2,0.7,3.61,0.7,2.58,2.58,0.443,0,0,-1.2,2
ENSMUSG00000029482,AACS,acetoacetyl-CoA synthetase,cytoplasm|cytosol|,liver development|lipid metabolic process|fatty acid metabolic process|response to nutrient|metabolic process|response to organonitrogen compound|response to organic cyclic compound|positive regulation of insulin secretion|response to oleic acid|response to drug|response to ethanol|cellular response to glucose stimulus|,nucleotide binding|catalytic activity|ATP binding|ligase activity|acetoacetate-CoA ligase activity|butyrate-CoA ligase activity|,10,-0.9,4.66,10,-0.2,0.265,-0.8,2.57,-2.57,0.444,0,0,-2,0.4
ENSMUSG00000022051,BNIP3L,BCL2/adenovirus E1B interacting protein 3-like,nucleus|nuclear envelope|nuclear envelope|mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial outer membrane|mitochondrial outer membrane|endoplasmic reticulum|endoplasmic reticulum|cytosol|membrane|integral component of membrane|,apoptotic process|mitochondrial protein catabolic process|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of programmed cell death|defense response to virus|defense response to virus|mitochondrial outer membrane permeabilization|,protein binding|lamin binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|protein heterodimerization activity|,10,0.2,1.53,10,-0.3,1.92,0.3,2.56,2.56,0.445,0,0,-1,1.2
ENSMUSG00000028393,ALAD,"aminolevulinate, delta-, dehydratase",extracellular space|nucleus|cytosol|extracellular vesicular exosome|,porphyrin-containing compound biosynthetic process|heme biosynthetic process|heme biosynthetic process|response to nutrient|metabolic process|response to organic substance|response to metal ion|response to zinc ion|tetrapyrrole biosynthetic process|response to drug|response to ethanol|response to arsenic-containing substance|response to cadmium ion|protein homooligomerization|cellular response to interleukin-4|,catalytic activity|porphobilinogen synthase activity|porphobilinogen synthase activity|zinc ion binding|lyase activity|lead ion binding|identical protein binding|identical protein binding|metal ion binding|,10,-0.2,0.831,10,-0.2,1.91,-0.2,2.56,-2.56,0.445,0,0,-1.4,0.6
ENSMUSG00000025892,GRIA4,"glutamate receptor, ionotropic, AMPA4 (alpha 4)",plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|dendrite|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|kainate selective glutamate receptor complex|cell projection|neuronal cell body|terminal bouton|synapse|synapse|postsynaptic membrane|,"transport|ion transport|synaptic transmission|ion transmembrane transport|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|regulation of synaptic transmission|positive regulation of synaptic transmission, glutamatergic|",receptor activity|ionotropic glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|,10,-0.4,1.68,10,-0.8,1.18,-0.3,2.54,-2.54,0.447,0,0,-1.8,0.2
ENSMUSG00000035818,PLEKHS1,"pleckstrin homology domain containing, family S member 1",cellular_component|,biological_process|,molecular_function|,10,-0.2,1.29,10,-0.3,1.44,-0.3,2.54,-2.54,0.447,0,0,-1.5,0.5
ENSMUSG00000031832,TAF1C,"TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C",RNA polymerase I transcription factor complex|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase I promoter|",DNA binding|protein binding|,10,0.4,2.92,10,0.1,0.0124,0.4,2.53,2.53,0.448,0,0,-0.9,1.6
ENSMUSG00000032299,COMMD4,COMM domain containing 4,cytoplasm|,biological_process|,molecular_function|,10,-0.6,0.31,10,-0.3,2.54,-0.3,2.51,-2.51,0.45,0,0,-1.3,1.5
ENSMUSG00000022542,12-Sep,septin 12,spindle|microtubule cytoskeleton|midbody|perinuclear region of cytoplasm|sperm annulus|,None,nucleotide binding|GTP binding|protein homodimerization activity|,10,1.3,5.69,10,-0.1,0.343,1.2,2.51,2.51,0.45,0,0,-0.2,2
ENSMUSG00000038170,PDE4DIP,phosphodiesterase 4D interacting protein (myomegalin),nucleus|cytoplasm|Golgi apparatus|Golgi apparatus|centrosome|centrosome|cytoskeleton|myofibril|myofibril|,cellular protein complex assembly|cellular protein complex assembly|,protein binding|enzyme binding|enzyme binding|,10,1.3,5.19,10,0.1,0.347,1.2,2.5,2.5,0.45,0,0,-0.2,2
ENSMUSG00000024812,TJP2,tight junction protein 2,nucleus|cytoplasm|plasma membrane|plasma membrane|gap junction|tight junction|cell surface|membrane|cell junction|cell junction|,None,protein binding|protein C-terminus binding|,10,0,0,10,-0.4,3.42,-0.3,2.5,-2.5,0.45,0,0,-1.5,0.4
ENSMUSG00000025597,KLHL4,kelch-like 4,None,biological_process|,molecular_function|,10,-0.2,0.488,10,0.4,2.56,0.2,2.48,2.48,0.452,0,0,-0.7,1.4
ENSMUSG00000066512,KLK1B5,kallikrein 1-related peptidase b5,nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.4,2.96,10,-1.2,5.74,-1.2,2.47,-2.47,0.453,0,0,-2,0.7
ENSMUSG00000029621,ARPC1A,"actin related protein 2/3 complex, subunit 1A",cytoplasm|cytoskeleton|Arp2/3 protein complex|extracellular vesicular exosome|,biological_process|regulation of actin filament polymerization|,molecular_function|actin binding|,10,-0.4,4.98,10,0.2,0.474,-0.4,2.47,-2.47,0.453,0,0,-1.6,0.9
ENSMUSG00000042961,EGFLAM,"EGF-like, fibronectin type III and laminin G domains",extracellular region|proteinaceous extracellular matrix|basement membrane|interstitial matrix|cell junction|extracellular matrix|synapse|,positive regulation of cell-substrate adhesion|peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|extracellular matrix organization|,protein binding|glycosaminoglycan binding|,10,0.4,2.62,10,-0.4,0.387,0.4,2.47,2.47,0.453,0,0,-0.7,1.7
ENSMUSG00000011958,BNIP2,BCL2/adenovirus E1B interacting protein 2,nuclear envelope|cytoplasm|centriole|cytosol|spindle pole centrosome|intracellular membrane-bounded organelle|,blastocyst development|apoptotic process|apoptotic process|positive regulation of MAPK cascade|positive regulation of MAPK cascade|positive regulation of neuron differentiation|positive regulation of small GTPase mediated signal transduction|striated muscle cell differentiation|centrosome organization|,identical protein binding|,10,0.2,0.527,10,0.4,2.45,0.4,2.46,2.46,0.454,0,0,-0.8,1.6
ENSMUSG00000032815,FANCA,"Fanconi anemia, complementation group A",nucleus|nucleolus|cytoplasm|Fanconi anaemia nuclear complex|,DNA repair|cellular response to DNA damage stimulus|male meiosis|male gonad development|female gonad development|regulation of cell proliferation|,None,10,-0.4,3.34,10,0.4,0.793,-0.3,2.44,-2.44,0.456,0,0,-1.4,1
ENSMUSG00000023885,THBS2,thrombospondin 2,extracellular region|basement membrane|extracellular matrix|,cell adhesion|negative regulation of angiogenesis|negative regulation of angiogenesis|positive regulation of synapse assembly|,calcium ion binding|protein binding|heparin binding|,10,0.2,1.14,10,0.5,1.82,0.2,2.44,2.44,0.456,0,0,-1.2,1.5
ENSMUSG00000022074,TNFRSF10B,"tumor necrosis factor receptor superfamily, member 10b",membrane|integral component of membrane|,apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|signal transduction|extrinsic apoptotic signaling pathway via death domain receptors|TRAIL-activated apoptotic signaling pathway|regulation of apoptotic process|extrinsic apoptotic signaling pathway|,protease binding|transcription factor binding|cysteine-type endopeptidase activator activity involved in apoptotic process|TRAIL binding|,10,0.1,0.535,10,0.3,2.32,0.2,2.42,2.42,0.458,0,0,-0.8,1.4
ENSMUSG00000038542,PCID2,PCI domain containing 2,cellular_component|,"negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of mRNA stability|positive regulation of B cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|spleen development|positive regulation of mitotic cell cycle spindle assembly checkpoint|positive regulation of mitotic cell cycle spindle assembly checkpoint|negative regulation of cysteine-type endopeptidase activity|",None,10,0.6,3.31,10,0.2,0.0805,0.4,2.39,2.39,0.461,0,0,-0.7,1.8
ENSMUSG00000053465,HS6ST3,heparan sulfate 6-O-sulfotransferase 3,membrane|integral component of membrane|,"heparan sulfate proteoglycan biosynthetic process, enzymatic modification|","N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,-0.6,0.263,10,-0.4,2.5,-0.4,2.35,-2.35,0.465,0,0,-1.6,1
ENSMUSG00000026285,PDCD1,programmed cell death 1,external side of plasma membrane|membrane|integral component of membrane|,immune system process|apoptotic process|,protein binding|,10,-0.2,0.324,10,-0.3,2.24,-0.2,2.33,-2.33,0.467,0,0,-1.4,0.9
ENSMUSG00000037526,ATG14,autophagy related 14,nucleus|cytoplasm|autophagic vacuole|autophagic vacuole|endoplasmic reticulum|axoneme|membrane|pre-autophagosomal structure membrane|pre-autophagosomal structure membrane|ER-mitochondrion membrane contact site|phagocytic vesicle|,autophagic vacuole assembly|autophagic vacuole assembly|autophagy|endosome to lysosome transport|positive regulation of autophagy|regulation of triglyceride metabolic process|,protein binding|,10,-0.1,0.0163,10,0.3,2.85,0.2,2.33,2.33,0.467,0,0,-1.4,1.2
ENSMUSG00000036023,PARP2,"poly (ADP-ribose) polymerase family, member 2",nucleus|nucleus|nucleoplasm|nucleoplasm|nucleolus|nucleolus|,DNA repair|base-excision repair|protein ADP-ribosylation|extrinsic apoptotic signaling pathway|,"DNA binding|NAD+ ADP-ribosyltransferase activity|protein binding|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.5,4.6,10,0,0,-0.4,2.32,-2.32,0.468,0,0,-1.6,1.2
ENSMUSG00000046186,CD109,CD109 antigen,cellular_component|extracellular region|extracellular space|plasma membrane|membrane|anchored component of membrane|,negative regulation of protein phosphorylation|hair follicle development|negative regulation of peptidase activity|negative regulation of keratinocyte proliferation|negative regulation of transforming growth factor beta receptor signaling pathway|regulation of keratinocyte differentiation|negative regulation of wound healing|osteoclast fusion|,endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|transforming growth factor beta binding|,10,0.3,2.77,10,0.1,0.149,0.2,2.32,2.32,0.468,0,0,-0.5,1.5
ENSMUSG00000022219,CIDEB,"cell death-inducing DNA fragmentation factor, alpha subunit-like effector B",intracellular|lipid particle|cytosol|,apoptotic process|regulation of apoptotic process|execution phase of apoptosis|,identical protein binding|,10,-0.2,0.865,10,-0.6,1.78,-0.2,2.32,-2.32,0.468,0,0,-1.6,1.5
ENSMUSG00000034341,WBP2,WW domain binding protein 2,nuclear chromatin|,"transcription from RNA polymerase II promoter|establishment of protein localization|positive regulation of gene expression, epigenetic|positive regulation of transcription from RNA polymerase II promoter|cellular response to estrogen stimulus|positive regulation of histone H3-K14 acetylation|",RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II transcription coactivator activity|protein binding|chromatin DNA binding|,10,-0.5,4.97,10,0.1,0.572,0.4,2.31,2.31,0.469,0,0,-1.3,1.4
ENSMUSG00000031950,GABARAPL2,gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2,Golgi membrane|Golgi membrane|autophagic vacuole membrane|intracellular|intracellular|cell|cytoplasm|autophagic vacuole|Golgi apparatus|cytoplasmic vesicle|,transport|intra-Golgi vesicle-mediated transport|autophagy|protein transport|negative regulation of proteasomal protein catabolic process|,protein binding|,10,-0.9,4.34,10,0.7,4.2,0.3,2.31,2.31,0.469,0,0,-1.9,1.3
ENSMUSG00000031710,UCP1,"uncoupling protein 1 (mitochondrial, proton carrier)",mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial membrane|,regulation of transcription from RNA polymerase II promoter|transport|mitochondrial transport|proton transport|proton transport|transmembrane transport|,protein binding|oxidative phosphorylation uncoupler activity|oxidative phosphorylation uncoupler activity|,10,0,0,10,0.6,4.03,0.2,2.3,2.3,0.469,0,0,-0.5,1.7
ENSMUSG00000036779,PAPD5,PAP associated domain containing 5,cellular_component|nucleus|cytoplasm|,rRNA processing|mRNA processing|cell cycle|mitotic nuclear division|cell division|histone mRNA catabolic process|,DNA binding|DNA-directed DNA polymerase activity|polynucleotide adenylyltransferase activity|transferase activity|nucleotidyltransferase activity|poly(A) RNA binding|metal ion binding|,10,0.1,0.545,10,0.4,2.19,0.2,2.3,2.3,0.469,0,0,-0.6,1.5
ENSMUSG00000006005,TPR,"translocated promoter region, nuclear basket protein","chromosome, centromeric region|kinetochore|nucleus|nuclear envelope|nuclear envelope|nuclear pore|nuclear pore|chromosome|cytoplasm|cytoskeleton|cytoplasmic dynein complex|membrane|extrinsic component of membrane|nuclear membrane|nuclear periphery|nuclear periphery|nuclear inclusion body|nuclear inclusion body|nuclear pore nuclear basket|mitotic spindle|",negative regulation of transcription from RNA polymerase II promoter|MAPK import into nucleus|RNA import into nucleus|RNA export from nucleus|protein import into nucleus|transport|cell cycle|mitotic nuclear division|mitotic spindle assembly checkpoint|regulation of mitotic sister chromatid separation|protein transport|positive regulation of heterochromatin assembly|mRNA export from nucleus in response to heat stress|cellular response to heat|cellular response to interferon-alpha|positive regulation of protein import into nucleus|negative regulation of translational initiation|positive regulation of protein export from nucleus|negative regulation of RNA export from nucleus|mRNA transport|cell division|response to epidermal growth factor|positive regulation of mitotic cell cycle spindle assembly checkpoint|positive regulation of intracellular protein transport|regulation of spindle assembly involved in mitosis|,chromatin binding|mRNA binding|nucleocytoplasmic transporter activity|protein binding|tubulin binding|heat shock protein binding|protein homodimerization activity|poly(A) RNA binding|mitogen-activated protein kinase binding|dynein complex binding|,10,-0.1,0.242,10,-0.5,3.16,-0.4,2.29,-2.29,0.471,0,0,-1.6,0.4
ENSMUSG00000021364,ELOVL2,"elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2",endoplasmic reticulum|membrane|integral component of membrane|,"very long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation, polyunsaturated fatty acid|fatty acid elongation, polyunsaturated fatty acid|fatty acid elongation, polyunsaturated fatty acid|very long-chain fatty acid biosynthetic process|very long-chain fatty acid biosynthetic process|very long-chain fatty acid biosynthetic process|","fatty acid elongase activity|fatty acid elongase activity|transferase activity|transferase activity, transferring acyl groups other than amino-acyl groups|",10,-0.2,0.639,10,0.5,3.23,0.4,2.29,2.29,0.471,0,0,-0.8,1.6
ENSMUSG00000002814,TOP3A,topoisomerase (DNA) III alpha,chromosome|PML body|,DNA topological change|,nucleic acid binding|DNA binding|DNA topoisomerase activity|DNA topoisomerase type I activity|zinc ion binding|isomerase activity|metal ion binding|,8,0.1,0.32,8,0.3,2.36,0.3,2.28,2.28,0.471,0,0,-1.4,1.6
ENSMUSG00000043091,TUBA1C,"tubulin, alpha 1C",nucleus|cytoplasm|cytoskeleton|microtubule|cytoplasmic microtubule|protein complex|,GTP catabolic process|microtubule-based process|biological_process|protein polymerization|,nucleotide binding|molecular_function|GTPase activity|structural constituent of cytoskeleton|GTP binding|,6,-0.1,0.0173,6,0.6,3.57,0.5,2.28,2.28,0.471,0,0,-0.8,2
ENSMUSG00000038060,DLEC1,deleted in lung and esophageal cancer 1,cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0.8,2.73,0.6,2.26,2.26,0.474,0,0,-0.3,1.9
ENSMUSG00000058672,TUBB2A,"tubulin, beta 2A class IIA",nucleus|cytoplasm|cytoskeleton|microtubule|protein complex|extracellular vesicular exosome|,GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,-0.1,0.477,10,0.3,2.6,0.2,2.26,2.26,0.474,0,0,-1.1,1.3
ENSMUSG00000040562,GSTM2,"glutathione S-transferase, mu 2",cytoplasm|cytosol|plasma membrane|protein complex|,glutathione metabolic process|metabolic process|nitrobenzene metabolic process|xenobiotic catabolic process|cellular detoxification of nitrogen compound|,glutathione transferase activity|glutathione transferase activity|transferase activity|enzyme binding|protein homodimerization activity|protein homodimerization activity|glutathione binding|protein heterodimerization activity|,10,0.5,4.88,10,0,0,0.5,2.24,2.24,0.476,0,0,-0.5,1.8
ENSMUSG00000024120,LRPPRC,leucine-rich PPR-motif containing,condensed nuclear chromosome|nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrion|cytoskeleton|microtubule|membrane|membrane|ribonucleoprotein complex|mitochondrial nucleoid|perinuclear region of cytoplasm|,"negative regulation of mitochondrial RNA catabolic process|negative regulation of mitochondrial RNA catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transport|mRNA transport|regulation of mitochondrial translation|",DNA binding|single-stranded DNA binding|RNA binding|protein binding|poly(A) RNA binding|beta-tubulin binding|,10,0.7,2.6,10,0.3,1.37,0.3,2.22,2.22,0.478,0,0,-0.3,1.8
ENSMUSG00000094686,CCL21A,chemokine (C-C motif) ligand 21A (serine),None,lymph node development|induction of positive chemotaxis|cell chemotaxis|positive regulation of T cell migration|,chemokine activity|chemokine receptor binding|,10,-0.3,2.09,10,-0.2,0.307,-0.3,2.22,-2.22,0.478,0,0,-1.4,1.2
ENSMUSG00000017861,MYBL2,myeloblastosis oncogene-like 2,nucleus|nucleus|Myb complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell cycle|positive regulation of transcription from RNA polymerase II promoter|spindle assembly involved in mitosis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|,10,0.7,0.953,10,0.3,2.25,0.5,2.21,2.21,0.479,0,0,-0.4,1.9
ENSMUSG00000044339,ALKBH2,"alkB, alkylation repair homolog 2 (E. coli)",nucleus|,DNA repair|DNA dealkylation involved in DNA repair|cellular response to DNA damage stimulus|oxidative DNA demethylation|oxidation-reduction process|DNA demethylation|,"ferrous iron binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|cytosine C-5 DNA demethylase activity|cytosine C-5 DNA demethylase activity|",10,0.3,1.97,9,0.1,0.553,0.2,2.21,2.21,0.479,0,0,-0.5,1.7
ENSMUSG00000005262,UFD1L,ubiquitin fusion degradation 1 like,nucleus|cytoplasm|,ubiquitin-dependent protein catabolic process|,receptor binding|protein complex binding|,10,0.3,2.3,10,0.1,0.162,0.2,2.21,2.21,0.479,0,0,-0.9,1.5
ENSMUSG00000022613,MIOX,myo-inositol oxygenase,cytoplasm|extracellular vesicular exosome|,inositol catabolic process|oxidation-reduction process|,"aldo-keto reductase (NADP) activity|iron ion binding|ferric iron binding|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H|metal ion binding|inositol oxygenase activity|NADP binding|",10,0.8,4.65,10,0.1,0.0255,0.6,2.2,2.2,0.48,0,0,-0.2,2
ENSMUSG00000028255,CLCA3,chloride channel calcium activated 3,extracellular region|microvillus|integral component of membrane|secretory granule|zymogen granule membrane|,transport|ion transport|calcium ion transport|chloride transport|chloride transmembrane transport|,chloride channel activity|,10,-0.3,2.46,10,-0.1,0.39,-0.2,2.2,-2.2,0.48,0,0,-1.4,1.3
ENSMUSG00000040537,ADAM22,a disintegrin and metallopeptidase domain 22,extracellular region|membrane|integral component of membrane|,proteolysis|integrin-mediated signaling pathway|adult locomotory behavior|Schwann cell differentiation|myelination in peripheral nervous system|gliogenesis|,metalloendopeptidase activity|protein binding|metallopeptidase activity|zinc ion binding|,10,-0.4,2,10,-0.2,0.738,-0.3,2.18,-2.18,0.482,0,0,-1.6,0.5
ENSMUSG00000019817,PLAGL1,pleiomorphic adenoma gene-like 1,nucleus|nucleus|cytoplasm|Golgi apparatus|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|regulation of gene expression|skeletal muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter|,RNA polymerase II regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|protein binding|metal ion binding|,10,-0.6,1.2,10,0.2,1.21,0.2,2.17,2.17,0.483,0,0,-1.4,1.3
ENSMUSG00000004895,PRCC,papillary renal cell carcinoma (translocation-associated),nucleus|intracellular membrane-bounded organelle|,mitotic cell cycle checkpoint|,molecular_function|,10,0.2,0.29,10,-0.5,3.68,-0.4,2.15,-2.15,0.485,0,0,-1.6,0.7
ENSMUSG00000051147,NAT2,N-acetyltransferase 2 (arylamine N-acetyltransferase),cytoplasm|cytosol|,metabolic process|,"arylamine N-acetyltransferase activity|arylamine N-acetyltransferase activity|arylamine N-acetyltransferase activity|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,1.3,5.55,10,-0.5,3.66,1.2,2.15,2.15,0.485,0,0,-1,2
ENSMUSG00000060445,SYCP2,synaptonemal complex protein 2,synaptonemal complex|synaptonemal complex|lateral element|nucleus|chromosome|,mitotic G1 phase|cell cycle|meiotic nuclear division|male meiosis|female meiotic division|fertilization|organ morphogenesis|negative regulation of apoptotic process|male genitalia morphogenesis|cell division|,DNA binding|protein binding|protein heterodimerization activity|,10,0.3,1.49,10,0.3,0.802,0.3,2.13,2.13,0.488,0,0,-0.5,1.7
ENSMUSG00000021177,TDP1,tyrosyl-DNA phosphodiesterase 1,nucleus|,single strand break repair|single strand break repair|DNA repair|DNA repair|double-strand break repair|cellular response to DNA damage stimulus|,"double-stranded DNA binding|single-stranded DNA binding|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|photoreceptor cyclic-nucleotide phosphodiesterase activity|nuclease activity|exonuclease activity|phosphoric diester hydrolase activity|hydrolase activity|3'-tyrosyl-DNA phosphodiesterase activity|7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity|inositol phosphosphingolipid phospholipase activity|inositol phosphorylceramide phospholipase activity|mannosyl-inositol phosphorylceramide phospholipase activity|mannosyl-diinositol phosphorylceramide phospholipase activity|",10,0.4,2.83,10,0.1,0.325,0.3,2.12,2.12,0.489,0,0,-0.6,1.6
ENSMUSG00000053870,FPGT,fucose-1-phosphate guanylyltransferase,cellular_component|,biological_process|,molecular_function|transferase activity|nucleotidyltransferase activity|,10,0.1,0.326,10,-0.3,3.72,-0.2,2.12,-2.12,0.489,0,0,-1.4,0.9
ENSMUSG00000049734,TREX1,three prime repair exonuclease 1,nucleus|nucleolus|cytoplasm|endoplasmic reticulum|membrane|,"DNA catabolic process, exonucleolytic|DNA metabolic process|cellular response to interferon-beta|nucleic acid phosphodiester bond hydrolysis|",nucleic acid binding|double-stranded DNA binding|single-stranded DNA binding|nuclease activity|exonuclease activity|protein binding|3'-5'-exodeoxyribonuclease activity|3'-5' exonuclease activity|exodeoxyribonuclease III activity|hydrolase activity|MutLalpha complex binding|MutSalpha complex binding|adenyl deoxyribonucleotide binding|protein homodimerization activity|metal ion binding|,10,-0.3,1.92,10,1,1.07,-0.2,2.09,-2.09,0.492,0,0,-1.3,1.7
ENSMUSG00000020581,AGR2,anterior gradient 2,extracellular region|mitochondrion|endoplasmic reticulum|,lung goblet cell differentiation|mucus secretion|,dystroglycan binding|,10,-0.1,0.206,10,-0.6,3.64,-0.5,2.08,-2.08,0.493,0,0,-1.7,0.2
ENSMUSG00000030878,CDR2,cerebellar degeneration-related 2,cytoplasm|,biological_process|,molecular_function|,10,-0.1,0.0675,10,-0.9,4.36,-0.3,2.06,-2.06,0.495,0,0,-1.9,0.1
ENSMUSG00000027479,MAPRE1,"microtubule-associated protein, RP/EB family, member 1",cytoplasm|Golgi apparatus|centrosome|spindle|cytoskeleton|microtubule|microtubule|cytoplasmic microtubule|microtubule cytoskeleton|cortical microtubule cytoskeleton|cell projection membrane|microtubule plus-end|cell projection|,cell cycle|mitotic nuclear division|regulation of microtubule polymerization|negative regulation of microtubule polymerization|protein localization to microtubule|protein localization to microtubule|cell division|positive regulation of microtubule plus-end binding|positive regulation of microtubule plus-end binding|,protein binding|microtubule binding|poly(A) RNA binding|microtubule plus-end binding|,10,0,0,10,1.1,3.36,0.2,2.06,2.06,0.495,0,0,-0.3,2
ENSMUSG00000005057,SH2B2,SH2B adaptor protein 2,stress fiber|ruffle|cytoplasm|cytoplasm|actin filament|plasma membrane|plasma membrane|membrane|,B-1 B cell homeostasis|nervous system development|insulin receptor signaling pathway|positive regulation of signal transduction|positive regulation of signal transduction|cytokine-mediated signaling pathway|regulation of metabolic process|actin cytoskeleton organization|actin cytoskeleton organization|intracellular signal transduction|intracellular signal transduction|glucose homeostasis|negative regulation of glucose import|regulation of JAK-STAT cascade|regulation of Ras protein signal transduction|regulation of immune response|antigen receptor-mediated signaling pathway|brown fat cell differentiation|,signal transducer activity|transmembrane receptor protein tyrosine kinase adaptor activity|SH3/SH2 adaptor activity|SH3/SH2 adaptor activity|protein binding|JAK pathway signal transduction adaptor activity|identical protein binding|,10,0,0,10,0.3,2.87,0.3,2.05,2.05,0.497,0,0,-0.5,1.6
ENSMUSG00000022615,TYMP,thymidine phosphorylase,None,pyrimidine nucleobase metabolic process|pyrimidine nucleoside metabolic process|chemotaxis|metabolic process|organ morphogenesis|,"phosphorylase activity|thymidine phosphorylase activity|pyrimidine-nucleoside phosphorylase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring pentosyl groups|",10,0.1,0.398,10,0.3,1.95,0.2,2.04,2.04,0.498,0,0,-0.6,1.6
ENSMUSG00000019777,HDAC2,histone deacetylase 2,histone deacetylase complex|chromatin|nuclear chromatin|nuclear chromatin|heterochromatin|nucleus|nucleus|replication fork|transcription factor complex|cytoplasm|Sin3 complex|NuRD complex|transcriptional repressor complex|ESC/E(Z) complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|maintenance of chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|protein deacetylation|positive regulation of cell proliferation|positive regulation of cell proliferation|epidermal cell differentiation|positive regulation of receptor biosynthetic process|negative regulation of neuron projection development|negative regulation of neuron projection development|dendrite development|chromatin modification|histone deacetylation|histone deacetylation|histone deacetylation|hippocampus development|neuron differentiation|circadian regulation of gene expression|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|ATP-dependent chromatin remodeling|negative regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of proteolysis|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|positive regulation of oligodendrocyte differentiation|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of protein kinase B signaling|cardiac muscle cell development|negative regulation of cardiac muscle cell proliferation|regulation of sarcomere organization|hair follicle placode formation|eyelid development in camera-type eye|fungiform papilla formation|histone H3 deacetylation|histone H4 deacetylation|negative regulation of canonical Wnt signaling pathway|regulation of protein deacetylation|negative regulation of intrinsic apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|core promoter binding|RNA polymerase II repressing transcription factor binding|chromatin binding|sequence-specific DNA binding transcription factor activity|histone deacetylase activity|histone deacetylase activity|histone deacetylase activity|protein binding|transcription factor binding|transcription factor binding|hydrolase activity|deacetylase activity|enzyme binding|enzyme binding|heat shock protein binding|histone deacetylase activity (H3-K14 specific)|chromatin DNA binding|nucleosomal DNA binding|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|protein deacetylase activity|protein deacetylase activity|histone deacetylase activity (H4-K16 specific)|Krueppel-associated box domain binding|sequence-specific DNA binding|poly(A) RNA binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,-0.4,3.72,10,0,0,-0.3,2.04,-2.04,0.498,0,0,-1.6,0.5
ENSMUSG00000000326,COMT,catechol-O-methyltransferase,cytoplasm|mitochondrion|cytosol|membrane|integral component of membrane|axon|dendrite|dendritic spine|cell body|postsynaptic membrane|extracellular vesicular exosome|,catecholamine metabolic process|female pregnancy|learning|short-term memory|estrogen metabolic process|catechol-containing compound metabolic process|cellular response to phosphate starvation|methylation|negative regulation of renal sodium excretion|neurotransmitter catabolic process|dopamine metabolic process|dopamine metabolic process|dopamine catabolic process|negative regulation of dopamine metabolic process|response to pain|multicellular organismal reproductive process|negative regulation of smooth muscle cell proliferation|positive regulation of homocysteine metabolic process|regulation of sensory perception of pain|,magnesium ion binding|methyltransferase activity|O-methyltransferase activity|catechol O-methyltransferase activity|catechol O-methyltransferase activity|catechol O-methyltransferase activity|transferase activity|metal ion binding|,10,-0.4,1.96,10,-0.1,0.224,-0.4,2.03,-2.03,0.499,0,0,-1.5,1.2
ENSMUSG00000030979,UROS,uroporphyrinogen III synthase,mitochondrion|cytosol|,porphyrin-containing compound biosynthetic process|porphyrin-containing compound biosynthetic process|uroporphyrinogen III biosynthetic process|heme biosynthetic process|tetrapyrrole biosynthetic process|,uroporphyrinogen-III synthase activity|uroporphyrinogen-III synthase activity|uroporphyrinogen-III synthase activity|uroporphyrinogen-III synthase activity|lyase activity|cofactor binding|,10,-0.2,0.176,10,-0.2,1.98,-0.2,2.02,-2.02,0.5,0,0,-1.5,0.8
ENSMUSG00000000555,ITGA5,integrin alpha 5 (fibronectin receptor alpha),cytoplasm|cell-cell junction|focal adhesion|integrin complex|external side of plasma membrane|cell surface|membrane|integral component of membrane|ruffle membrane|synapse|,cell-substrate junction assembly|cell adhesion|heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|integrin-mediated signaling pathway|memory|positive regulation of cell-substrate adhesion|positive regulation of cell migration|cell-substrate adhesion|cell-cell adhesion mediated by integrin|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of anoikis|,epidermal growth factor receptor binding|integrin binding|integrin binding|protein binding|metal ion binding|cell adhesion molecule binding|,10,0.3,0.651,10,0.3,1.53,0.3,2.02,2.02,0.5,0,0,-0.4,1.7
ENSMUSG00000034329,BRIP1,BRCA1 interacting protein C-terminal helicase 1,nucleus|cytoplasm|nuclear membrane|,nucleobase-containing compound metabolic process|DNA repair|regulation of transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|negative regulation of cell proliferation|,"nucleotide binding|nucleic acid binding|DNA binding|ATP-dependent DNA helicase activity|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.3,2.47,10,0.1,0.164,0.2,2.01,2.01,0.501,0,0,-0.7,1.5
ENSMUSG00000022429,DMC1,"DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination","chromosome, telomeric region|condensed nuclear chromosome|nucleus|nucleus|chromosome|",ovarian follicle development|oocyte maturation|DNA metabolic process|DNA repair|cell cycle|meiotic nuclear division|synapsis|reciprocal meiotic recombination|male meiosis I|gamete generation|spermatogenesis|spermatid development|,nucleotide binding|DNA binding|ATP binding|DNA-dependent ATPase activity|,10,0.5,2.95,10,-0.4,2.47,-0.3,2.01,-2.01,0.501,0,0,-1.2,1.5
ENSMUSG00000002190,CLGN,calmegin,nuclear envelope|endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|,protein folding|protein complex assembly|meiotic nuclear division|multicellular organismal development|spermatogenesis|single fertilization|binding of sperm to zona pellucida|cell differentiation|,calcium ion binding|protein binding|protein binding involved in protein folding|unfolded protein binding|,10,0.5,4.69,10,-0.2,0.872,0.4,1.99,1.99,0.504,0,0,-0.6,1.8
ENSMUSG00000052534,PBX1,pre B cell leukemia homeobox 1,nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|,"urogenital system development|branching involved in ureteric bud morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|steroid biosynthetic process|multicellular organismal development|sex differentiation|positive regulation of cell proliferation|organ morphogenesis|anterior/posterior pattern specification|proximal/distal pattern formation|proximal/distal pattern formation|positive regulation of G2/M transition of mitotic cell cycle|cell differentiation|regulation of ossification|adrenal gland development|embryonic limb morphogenesis|embryonic hemopoiesis|regulation of cell proliferation|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|spleen development|spleen development|thymus development|embryonic organ development|embryonic skeletal system development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|protein heterodimerization activity|,10,0.3,0.972,10,0.2,1.23,0.2,1.99,1.99,0.504,0,0,-0.5,1.7
ENSMUSG00000030225,DERA,2-deoxyribose-5-phosphate aldolase homolog (C. elegans),cytoplasm|extracellular vesicular exosome|,deoxyribonucleotide catabolic process|deoxyribonucleoside catabolic process|,catalytic activity|deoxyribose-phosphate aldolase activity|lyase activity|,10,0.6,2.54,10,0.1,0.0545,0.5,1.99,1.99,0.504,0,0,-0.4,1.9
ENSMUSG00000022070,BORA,"bora, aurora kinase A activator",meiotic spindle|,cell cycle|mitotic nuclear division|regulation of mitosis|regulation of protein localization|cell division|regulation of mitotic spindle organization|,protein kinase binding|,10,0.3,2.24,10,0.1,0.259,0.2,1.98,1.98,0.505,0,0,-0.7,1.6
ENSMUSG00000032743,D430042O09RIK,RIKEN cDNA D430042O09 gene,extracellular space|nucleus|plasma membrane|,biological_process|,molecular_function|,10,0,0,10,-1.3,5.3,-1.2,1.98,-1.98,0.505,0,0,-2,0.2
ENSMUSG00000042453,RELN,reelin,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|cytoplasm|cytoplasm|axon|dendrite|dendrite|neuron projection|neuronal cell body|perikaryon|,"cell morphogenesis involved in differentiation|neuron migration|neuron migration|neuron migration|proteolysis|cell adhesion|multicellular organismal development|axon guidance|central nervous system development|brain development|brain development|long-term memory|locomotory behavior|locomotory behavior|associative learning|glial cell differentiation|regulation of gene expression|positive regulation of neuron projection development|positive regulation of phosphatidylinositol 3-kinase signaling|dendrite development|dendrite development|cell migration|peptidyl-tyrosine phosphorylation|spinal cord patterning|dentate gyrus development|hippocampus development|cerebral cortex tangential migration|layer formation in cerebral cortex|cerebral cortex development|forebrain development|positive regulation of TOR signaling|positive regulation of CREB transcription factor activity|protein localization to synapse|reelin-mediated signaling pathway|thyroid hormone metabolic process|positive regulation of protein kinase activity|positive regulation of protein kinase activity|response to pain|positive regulation of peptidyl-tyrosine phosphorylation|regulation of behavior|regulation of synaptic transmission|positive regulation of small GTPase mediated signal transduction|positive regulation of synaptic transmission, glutamatergic|positive regulation of synaptic transmission, glutamatergic|positive regulation of dendritic spine morphogenesis|positive regulation of dendritic spine morphogenesis|positive regulation of protein tyrosine kinase activity|positive regulation of synapse maturation|postsynaptic density assembly|N-methyl-D-aspartate receptor clustering|postsynaptic density protein 95 clustering|receptor localization to synapse|lateral motor column neuron migration|positive regulation of long-term synaptic potentiation|positive regulation of lateral motor column neuron migration|regulation of N-methyl-D-aspartate selective glutamate receptor activity|positive regulation of excitatory postsynaptic membrane potential|positive regulation of excitatory postsynaptic membrane potential|positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|",peptidase activity|serine-type peptidase activity|hydrolase activity|metal ion binding|lipoprotein particle receptor binding|very-low-density lipoprotein particle receptor binding|,10,0.2,0.528,10,-1,5.13,-1,1.97,-1.97,0.506,0,0,-2,0.3
ENSMUSG00000005078,JKAMP,JNK1/MAPK8-associated membrane protein,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,response to unfolded protein|ER-associated ubiquitin-dependent protein catabolic process|,ubiquitin protein ligase binding|,10,0.2,1.66,10,0.2,0.43,0.2,1.95,1.95,0.508,0,0,-0.7,1.6
ENSMUSG00000057265,CCDC176,coiled-coil domain containing 176,cellular_component|cytoplasm|cytoskeleton|cilium|cell projection|,biological_process|,molecular_function|,10,0,0,10,0.7,4.5,0.6,1.94,1.94,0.509,0,0,-0.4,1.8
ENSMUSG00000032688,MALT1,mucosa associated lymphoid tissue lymphoma translocation gene 1,intracellular|nucleus|nucleolus|cytoplasm|cytosol|protein complex|,B-1 B cell differentiation|positive regulation of T cell cytokine production|proteolysis|apoptotic process|I-kappaB kinase/NF-kappaB signaling|activation of NF-kappaB-inducing kinase activity|response to fungus|protein ubiquitination|positive regulation of interleukin-2 production|T cell proliferation|B cell activation|regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|T cell receptor signaling pathway|T cell receptor signaling pathway|regulation of T cell receptor signaling pathway|positive regulation of T cell activation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|nuclear export|protein oligomerization|,protease binding|cysteine-type endopeptidase activity|ubiquitin-protein transferase activity|signal transducer activity|protein binding|peptidase activity|hydrolase activity|kinase activator activity|protein self-association|,10,-0.9,4.79,10,0,0,-0.9,1.94,-1.94,0.509,0,0,-2,0
ENSMUSG00000002326,GMPR2,guanosine monophosphate reductase 2,cellular_component|GMP reductase complex|,purine nucleobase metabolic process|nucleotide metabolic process|monocyte differentiation|GMP catabolic process|oxidation-reduction process|,catalytic activity|GMP reductase activity|oxidoreductase activity|metal ion binding|,10,0.2,0.958,10,0.2,1.13,0.2,1.93,1.93,0.51,0,0,-0.8,1.6
ENSMUSG00000033904,CCP110,centriolar coiled coil protein 110,cytoplasm|centrosome|centriole|cytoskeleton|protein complex|,centriole replication|cell projection organization|regulation of cytokinesis|centrosome duplication|,protein binding|,10,0.4,2.73,10,-0.3,0.0467,0.3,1.92,1.92,0.512,0,0,-0.8,1.7
ENSMUSG00000043099,HIC1,hypermethylated in cancer 1,chromatin|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|Wnt signaling pathway|negative regulation of Wnt signaling pathway|positive regulation of DNA damage response, signal transduction by p53 class mediator|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|histone deacetylase binding|sequence-specific DNA binding|metal ion binding|,10,1.5,2.3,10,1,0.793,1.3,1.92,1.92,0.512,0,0,-0.1,3
ENSMUSG00000044248,VMN1R45,vomeronasal 1 receptor 45,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|response to pheromone|,signal transducer activity|G-protein coupled receptor activity|pheromone receptor activity|,9,0.3,2.67,9,0,0,0.2,1.91,1.91,0.513,0,0,-0.7,1.7
ENSMUSG00000038539,ATF5,activating transcription factor 5,nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|post-embryonic development|regulation of gene expression|olfactory bulb interneuron differentiation|olfactory bulb interneuron development|olfactory lobe development|multicellular organism growth|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|negative regulation of astrocyte differentiation|negative regulation of neurogenesis|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|heat shock protein binding|sequence-specific DNA binding|,10,0.1,0.183,10,0.9,2.8,0.2,1.91,1.91,0.513,0,0,-0.6,1.9
ENSMUSG00000021198,UNC79,unc-79 homolog (C. elegans),cellular_component|membrane|integral component of membrane|,adult behavior|multicellular organism growth|behavioral response to ethanol|,molecular_function|,10,-0.5,4.08,10,0.1,0.25,0.2,1.88,1.88,0.516,0,0,-1.5,1
ENSMUSG00000039269,2300002M23RIK,RIKEN cDNA 2300002M23 gene,extracellular region|proteinaceous extracellular matrix|interstitial matrix|extracellular matrix|,extracellular matrix organization|,fibronectin binding|collagen binding|glycosaminoglycan binding|hyaluronic acid binding|heparin binding|laminin binding|collagen V binding|,10,0.1,0.0148,10,0.2,2.09,0.2,1.85,1.85,0.52,0,0,-0.7,1.6
ENSMUSG00000091964,BC037034,cDNA sequence BC037034,cellular_component|,biological_process|,molecular_function|,1,0,0,1,-0.7,2.44,-0.6,1.85,-1.85,0.52,0,0,-2,1.5
ENSMUSG00000027442,CST8,cystatin 8 (cystatin-related epididymal spermatogenic),extracellular region|cytoplasm|cell surface|,negative regulation of peptidase activity|,cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.4,4.02,10,-0.2,0.888,0.3,1.84,1.84,0.521,0,0,-1.1,1.4
ENSMUSG00000094443,GM4975,predicted gene 4975,None,None,None,10,0.3,2.12,10,0,0,0.2,1.82,1.82,0.524,0,0,-0.8,1.6
ENSMUSG00000066129,KNDC1,kinase non-catalytic C-lobe domain (KIND) containing 1,intracellular|dendrite|guanyl-nucleotide exchange factor complex|neuronal cell body|,positive regulation of protein phosphorylation|protein phosphorylation|small GTPase mediated signal transduction|phosphorylation|cerebellar granule cell differentiation|positive regulation of Ras GTPase activity|regulation of dendrite morphogenesis|regulation of dendrite development|regulation of small GTPase mediated signal transduction|,"protein serine/threonine kinase activity|guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|protein binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.573,10,0.2,1.39,0.2,1.82,1.82,0.524,0,0,-0.8,1.6
ENSMUSG00000002731,PRKRA,"protein kinase, interferon inducible double stranded RNA dependent activator",intracellular|cytoplasm|membrane|,protein phosphorylation|positive regulation of cell proliferation|production of siRNA involved in RNA interference|gene silencing by RNA|cellular response to oxidative stress|outer ear morphogenesis|middle ear morphogenesis|skeletal system morphogenesis|positive regulation of intrinsic apoptotic signaling pathway|,RNA binding|protein binding|protein kinase binding|protein homodimerization activity|poly(A) RNA binding|,9,-1,4.64,9,0.4,1.23,-0.9,1.81,-1.81,0.525,0,0,-2,0.7
ENSMUSG00000026141,COL19A1,"collagen, type XIX, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|,cell adhesion|multicellular organismal development|muscle organ development|skeletal muscle tissue development|cell differentiation|extracellular matrix organization|,None,9,-0.2,0.386,9,0.6,3.08,0.3,1.8,1.8,0.526,0,0,-1.1,1.6
ENSMUSG00000038526,CAR14,carbonic anhydrase 14,membrane|integral component of membrane|,regulation of pH|carbon dioxide transport|,carbonate dehydratase activity|carbonate dehydratase activity|lyase activity|metal ion binding|,10,-0.3,1.32,10,1.1,2.89,-0.3,1.79,-1.79,0.527,0,0,-0.8,2
ENSMUSG00000092118,FANCF,"Fanconi anemia, complementation group F",Fanconi anaemia nuclear complex|Fanconi anaemia nuclear complex|,ovarian follicle development|cellular response to DNA damage stimulus|spermatogenesis|protein ubiquitination|,ubiquitin-protein transferase activity|,10,0.2,1.34,10,0.2,0.588,0.2,1.79,1.79,0.527,0,0,-0.7,1.6
ENSMUSG00000027643,GHRH,growth hormone releasing hormone,extracellular region|extracellular space|extracellular space|intracellular|cell|neuron projection|terminal bouton|perikaryon|axon terminus|,"adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cardiac muscle cell apoptotic process|cAMP-mediated signaling|adenohypophysis development|growth hormone secretion|growth hormone secretion|growth hormone secretion|positive regulation of cAMP metabolic process|positive regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|response to food|positive regulation of multicellular organism growth|positive regulation of multicellular organism growth|positive regulation of multicellular organism growth|circadian sleep/wake cycle, non-REM sleep|positive regulation of transcription, DNA-templated|positive regulation of circadian sleep/wake cycle, non-REM sleep|positive regulation of hormone secretion|positive regulation of growth hormone secretion|",hormone activity|protein binding|growth hormone-releasing hormone activity|growth hormone-releasing hormone receptor binding|growth hormone-releasing hormone receptor binding|,10,0,0,10,0.3,3.05,0.2,1.79,1.79,0.527,0,0,-0.5,1.8
ENSMUSG00000020849,YWHAE,"tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide",cytoplasm|mitochondrion|kinesin complex|membrane|axon|extracellular vesicular exosome|,neuron migration|neuron migration|protein targeting|hippocampus development|cerebral cortex development|negative regulation of protein dephosphorylation|oxidation-reduction process|regulation of membrane repolarization|regulation of potassium ion transmembrane transporter activity|negative regulation of peptidyl-serine dephosphorylation|,monooxygenase activity|protein binding|potassium channel regulator activity|oxidoreductase activity|enzyme binding|protein domain specific binding|MHC class II protein complex binding|protein complex binding|histone deacetylase binding|ion channel binding|poly(A) RNA binding|protein heterodimerization activity|phosphoserine binding|phosphoprotein binding|,10,0.3,2.1,10,-0.4,1.93,0.2,1.78,1.78,0.528,0,0,-1.1,1.4
ENSMUSG00000022449,ADAMTS20,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|,proteolysis|integrin-mediated signaling pathway|positive regulation of signal transduction|extracellular matrix organization|negative regulation of apoptotic process|positive regulation of melanocyte differentiation|positive regulation of melanocyte differentiation|regulation of developmental pigmentation|regulation of developmental pigmentation|,endopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.9,1.55,10,0.2,1.63,0.2,1.77,1.77,0.53,0,0,-0.8,1.9
ENSMUSG00000036768,KIF15,kinesin family member 15,cytoplasm|cytoskeleton|kinesin complex|microtubule|membrane|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,-0.1,0.0293,10,-0.3,2.05,-0.3,1.76,-1.76,0.531,0,0,-1.6,0.8
ENSMUSG00000024805,PCGF5,polycomb group ring finger 5,nucleus|nucleolus|centrosome|PcG protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|zinc ion binding|metal ion binding|,10,-0.1,0.301,10,1,1.68,-0.2,1.76,-1.76,0.531,0,0,-1,1.9
ENSMUSG00000027425,CSRP2BP,cysteine and glycine-rich protein 2 binding protein,nucleus|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|cytoplasm|,G2/M transition of mitotic cell cycle|embryo development|histone acetylation|histone H3 acetylation|,histone acetyltransferase activity|protein binding|N-acetyltransferase activity|,10,-0.4,2.25,10,0.1,0.327,-0.3,1.75,-1.75,0.532,0,0,-1.7,0.8
ENSMUSG00000002996,HBP1,high mobility group box transcription factor 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Wnt signaling pathway|positive regulation of potassium ion transport|",DNA binding|RNA binding|protein binding|,10,-0.2,1.16,10,-0.4,0.907,-0.4,1.74,-1.74,0.533,0,0,-1.7,0.6
ENSMUSG00000016664,PACSIN2,protein kinase C and casein kinase substrate in neurons 2,nucleus|cytoplasm|cytoplasm|endosome|cytosol|cytoskeleton|plasma membrane|caveola|caveola|cell-cell junction|membrane|extrinsic component of membrane|cytoplasmic vesicle|cell projection|intracellular membrane-bounded organelle|recycling endosome membrane|extracellular vesicular exosome|,endocytosis|signal transduction|phosphorylation|actin cytoskeleton organization|protein localization to endosome|negative regulation of endocytosis|cell projection morphogenesis|caveola assembly|caveolin-mediated endocytosis|membrane tubulation|membrane tubulation|,protein binding|cytoskeletal protein binding|lipid binding|kinase activity|transferase activity|identical protein binding|phosphatidic acid binding|,10,0.2,0.841,10,0.3,1.12,0.2,1.74,1.74,0.533,0,0,-0.5,1.7
ENSMUSG00000022105,RB1,retinoblastoma 1,nucleus|nucleus|transcription factor complex|spindle|PML body|Rb-E2F complex|,"G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|negative regulation of protein kinase activity|cell cycle|cell cycle arrest|regulation of mitotic cell cycle|negative regulation of cell proliferation|negative regulation of cell proliferation|chromatin modification|neuron differentiation|sister chromatid biorientation|neuron projection development|maintenance of mitotic sister chromatid cohesion|glial cell apoptotic process|skeletal muscle cell differentiation|neuron maturation|negative regulation of apoptotic process|enucleate erythrocyte differentiation|regulation of lipid kinase activity|myoblast differentiation|positive regulation of macrophage differentiation|negative regulation of cell cycle|positive regulation of mitotic metaphase/anaphase transition|negative regulation of smoothened signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|digestive tract development|cell morphogenesis involved in neuron differentiation|negative regulation of epithelial cell proliferation|striated muscle cell differentiation|cell division|neuron apoptotic process|regulation of cell cycle|protein localization to chromosome, centromeric region|regulation of cohesin localization to chromatin|negative regulation of transcription involved in G1/S transition of mitotic cell cycle|hepatocyte apoptotic process|hepatocyte apoptotic process|negative regulation of G1/S transition of mitotic cell cycle|",core promoter binding|RNA polymerase II activating transcription factor binding|DNA binding|protein binding|transcription factor binding|transcription factor binding|enzyme binding|kinase binding|ubiquitin protein ligase binding|identical protein binding|phosphoprotein binding|,9,1,3.26,9,0.1,0.335,0.7,1.69,1.69,0.54,0,0,-0.2,2
ENSMUSG00000090626,TEX9,testis expressed gene 9,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,3.35,0.3,1.68,1.68,0.541,0,0,-0.9,1.5
ENSMUSG00000006362,CBFA2T3,"core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)",intracellular|nucleus|Golgi apparatus|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell differentiation|granulocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|",chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,0.2,0.262,10,-0.3,2.45,-0.2,1.68,-1.68,0.541,0,0,-1.4,1.1
ENSMUSG00000024525,IMPA2,inositol (myo)-1(or 4)-monophosphatase 2,cytoplasm|,inositol metabolic process|dephosphorylation|phosphatidylinositol phosphorylation|inositol phosphate dephosphorylation|,inositol monophosphate 1-phosphatase activity|inositol monophosphate 1-phosphatase activity|hydrolase activity|protein homodimerization activity|metal ion binding|inositol monophosphate 3-phosphatase activity|inositol monophosphate 4-phosphatase activity|inositol monophosphate phosphatase activity|,10,-0.2,1.1,10,-0.2,0.703,-0.2,1.67,-1.67,0.542,0,0,-1.7,0.7
ENSMUSG00000030838,USH1C,Usher syndrome 1C,photoreceptor outer segment|photoreceptor inner segment|cytoplasm|cytoskeleton|plasma membrane|stereocilium|apical part of cell|synapse|,G2/M transition of mitotic cell cycle|sensory perception of sound|sensory perception of sound|parallel actin filament bundle assembly|inner ear morphogenesis|auditory receptor cell differentiation|photoreceptor cell maintenance|neuromuscular process controlling balance|sensory perception of light stimulus|equilibrioception|actin filament bundle assembly|,protein binding|spectrin binding|myosin tail binding|,10,0.2,1.9,10,-0.1,0.29,0.2,1.67,1.67,0.542,0,0,-0.9,1.5
ENSMUSG00000029095,ABLIM2,actin-binding LIM protein 2,cytoplasm|actin cytoskeleton|myofibril|,"transcription, DNA-templated|cytoskeleton organization|actin cytoskeleton organization|positive regulation of transcription from RNA polymerase II promoter|",molecular_function|actin binding|zinc ion binding|metal ion binding|,10,-0.2,1.41,10,-0.3,0.393,-0.3,1.66,-1.66,0.544,0,0,-1.6,0.7
ENSMUSG00000029605,OAS1B,2'-5' oligoadenylate synthetase 1B,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,immune system process|immune response|response to virus|negative regulation of viral genome replication|innate immune response|defense response to virus|,RNA binding|double-stranded RNA binding|protein binding|ATP binding|transferase activity|,10,-0.2,0.634,10,-0.3,1.32,-0.2,1.66,-1.66,0.544,0,0,-1.6,0.7
ENSMUSG00000031511,ARHGEF7,Rho guanine nucleotide exchange factor (GEF7),cytoplasm|focal adhesion|lamellipodium|cell junction|growth cone|cell projection|neuron projection|neuronal cell body|protein complex|,hematopoietic progenitor cell differentiation|small GTPase mediated signal transduction|nervous system development|lamellipodium assembly|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of apoptotic process|positive regulation of GTPase activity|astrocyte cell migration|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|protein kinase binding|protein kinase binding|,10,-0.3,1.34,10,-0.4,0.531,-0.4,1.65,-1.65,0.545,0,0,-1.7,0.7
ENSMUSG00000038644,POLD1,"polymerase (DNA directed), delta 1, catalytic subunit",nucleotide-excision repair complex|nucleus|nucleus|cytoplasm|membrane|aggresome|delta DNA polymerase complex|delta DNA polymerase complex|,"mitotic S phase|DNA synthesis involved in DNA repair|nucleobase-containing compound metabolic process|DNA replication|DNA-dependent DNA replication|DNA-dependent DNA replication|base-excision repair, gap-filling|base-excision repair, gap-filling|nucleotide-excision repair, DNA gap filling|nucleotide-excision repair, DNA gap filling|regulation of mitotic cell cycle|DNA replication, removal of RNA primer|DNA replication proofreading|fatty acid homeostasis|DNA biosynthetic process|DNA biosynthetic process|nucleic acid phosphodiester bond hydrolysis|","nucleotide binding|nucleic acid binding|DNA binding|chromatin binding|DNA-directed DNA polymerase activity|DNA-directed DNA polymerase activity|nuclease activity|exonuclease activity|3'-5' exonuclease activity|transferase activity|nucleotidyltransferase activity|hydrolase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.3,1.3,10,-0.3,1.28,-0.3,1.65,-1.65,0.545,0,0,-1.5,1
ENSMUSG00000021835,BMP4,bone morphogenetic protein 4,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|cytoplasm|membrane-bounded vesicle|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|activation of MAPKK activity|skeletal system development|skeletal system development|ossification|angiogenesis|ovarian follicle development|blood vessel development|osteoblast differentiation|osteoblast differentiation|metanephros development|metanephros development|ureteric bud development|ureteric bud development|ureteric bud development|branching involved in ureteric bud morphogenesis|branching involved in ureteric bud morphogenesis|mesoderm formation|organ induction|kidney development|kidney development|kidney development|neural tube closure|positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|vasculature development|endochondral ossification|blood vessel endothelial cell proliferation involved in sprouting angiogenesis|chondrocyte differentiation|hematopoietic progenitor cell differentiation|hematopoietic progenitor cell differentiation|lymphoid progenitor cell differentiation|renal system process|BMP signaling pathway involved in heart induction|secondary heart field specification|type B pancreatic cell development|mesenchymal to epithelial transition involved in metanephros morphogenesis|common-partner SMAD protein phosphorylation|multicellular organismal development|germ cell development|mesodermal cell fate determination|heart development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|post-embryonic development|post-embryonic development|tissue development|anterior/posterior axis specification|specification of organ position|regulation of cell fate commitment|regulation of gene expression|regulation of gene expression|positive regulation of endothelial cell migration|positive regulation of endothelial cell migration|positive regulation of gene expression|negative regulation of gene expression|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of cell death|telencephalon development|dorsal/ventral neural tube patterning|telencephalon regionalization|telencephalon regionalization|pituitary gland development|cell differentiation|erythrocyte differentiation|monocyte differentiation|macrophage differentiation|lung development|embryonic limb morphogenesis|embryonic limb morphogenesis|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|positive regulation of BMP signaling pathway|forebrain development|forebrain development|positive regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of protein binding|negative regulation of chondrocyte differentiation|positive regulation of collagen biosynthetic process|negative regulation of T cell differentiation in thymus|negative regulation of immature T cell proliferation in thymus|protein localization to nucleus|embryonic hindlimb morphogenesis|tendon cell differentiation|deltoid tuberosity development|growth|negative regulation of phosphorylation|odontogenesis of dentin-containing tooth|odontogenesis of dentin-containing tooth|odontogenesis|regulation of odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|camera-type eye development|camera-type eye development|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|steroid hormone mediated signaling pathway|negative regulation of MAP kinase activity|cell fate commitment|regulation of cell differentiation|regulation of cell differentiation|positive regulation of cell differentiation|positive regulation of endothelial cell differentiation|positive regulation of epidermal cell differentiation|negative regulation of myoblast differentiation|positive regulation of neuron differentiation|positive regulation of osteoblast differentiation|positive regulation of ossification|positive regulation of ossification|negative regulation of cell cycle|negative regulation of mitosis|negative regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|lung alveolus development|mesodermal cell differentiation|intermediate mesodermal cell differentiation|camera-type eye morphogenesis|embryonic morphogenesis|anatomical structure formation involved in morphogenesis|regulation of smooth muscle cell proliferation|positive regulation of smooth muscle cell proliferation|neuron fate commitment|neuron fate commitment|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|embryonic skeletal system development|negative regulation of oligodendrocyte differentiation|smooth muscle tissue development|branching morphogenesis of an epithelial tube|positive regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|positive chemotaxis|smooth muscle cell differentiation|regulation of smooth muscle cell differentiation|regulation of smooth muscle cell differentiation|cartilage development|cardiac muscle cell differentiation|positive regulation of cardiac muscle fiber development|inner ear receptor cell differentiation|lens induction in camera-type eye|embryonic skeletal joint morphogenesis|embryonic skeletal joint morphogenesis|bone development|cranial suture morphogenesis|positive regulation of SMAD protein import into nucleus|regulation of pathway-restricted SMAD protein phosphorylation|SMAD protein signal transduction|SMAD protein signal transduction|lung morphogenesis|epithelium development|bronchus development|trachea development|trachea formation|epithelial tube branching involved in lung morphogenesis|branching involved in prostate gland morphogenesis|bud elongation involved in lung branching|epithelial cell proliferation involved in lung morphogenesis|bud dilation involved in lung branching|prostate gland morphogenesis|negative regulation of cell death|mammary gland formation|epithelial-mesenchymal cell signaling|negative regulation of prostatic bud formation|negative regulation of prostatic bud formation|regulation of branching involved in prostate gland morphogenesis|regulation of morphogenesis of a branching structure|regulation of cartilage development|positive regulation of cartilage development|positive regulation of branching involved in lung morphogenesis|BMP signaling pathway involved in ureter morphogenesis|BMP signaling pathway involved in renal system segmentation|pulmonary artery endothelial tube morphogenesis|negative regulation of thymocyte apoptotic process|positive regulation of ERK1 and ERK2 cascade|cellular response to growth factor stimulus|cellular response to dexamethasone stimulus|BMP signaling pathway involved in nephric duct formation|renal system development|negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway|specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway|glomerular capillary formation|negative regulation of glomerular mesangial cell proliferation|mesenchymal cell differentiation involved in kidney development|ureter epithelial cell differentiation|ureter smooth muscle cell differentiation|negative regulation of mesenchymal cell proliferation involved in ureter development|metanephric collecting duct development|positive regulation of kidney development|positive regulation of branching involved in ureteric bud morphogenesis|negative regulation of branching involved in ureteric bud morphogenesis|negative regulation of branching involved in ureteric bud morphogenesis|negative regulation of glomerulus development|negative regulation of metanephric S-shaped body morphogenesis|negative regulation of metanephric comma-shaped body morphogenesis|positive regulation of DNA-dependent DNA replication|negative regulation of cell proliferation involved in heart morphogenesis|mesenchymal cell differentiation involved in renal system development|",cytokine activity|protein binding|growth factor activity|heparin binding|chemoattractant activity|protein homodimerization activity|BMP receptor binding|,10,0.2,0.742,10,0.2,1.04,0.2,1.65,1.65,0.545,0,0,-0.9,1.5
ENSMUSG00000029397,RCHY1,ring finger and CHY zinc finger domain containing 1,ubiquitin ligase complex|nucleus|cytoplasm|,protein ubiquitination|positive regulation of protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein autoubiquitination|,"p53 binding|ubiquitin-protein transferase activity|receptor binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.523,10,-0.4,2.04,-0.4,1.65,-1.65,0.545,0,0,-1.7,0.7
ENSMUSG00000020474,POLM,"polymerase (DNA directed), mu",nucleus|,DNA repair|DNA recombination|cellular response to DNA damage stimulus|somatic hypermutation of immunoglobulin genes|B cell differentiation|,DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|DNA polymerase activity|metal ion binding|,9,0.2,1.58,9,0.1,0.195,0.2,1.64,1.64,0.546,0,0,-0.9,1.7
ENSMUSG00000055022,CNTN1,contactin 1,plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,cell adhesion|Notch signaling pathway|positive regulation of gene expression|positive regulation of sodium ion transport|positive regulation of neuron projection development|cerebellum development|neuron projection development|,glycoprotein binding|protein binding|carbohydrate binding|,10,0.1,0.171,10,0.2,1.73,0.2,1.64,1.64,0.546,0,0,-0.7,1.6
ENSMUSG00000071533,PCNP,PEST proteolytic signal containing nuclear protein,nucleus|,cell cycle|protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|,None,10,-0.1,0.579,10,-0.2,1.34,-0.2,1.64,-1.64,0.546,0,0,-1.5,1.1
ENSMUSG00000025958,CREB1,cAMP responsive element binding protein 1,chromatin|nuclear chromatin|nuclear chromatin|nucleus|nucleus|transcription factor complex|transcription factor complex|nuclear euchromatin|mitochondrion|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|transforming growth factor beta receptor signaling pathway|axonogenesis|lactation|memory|circadian rhythm|regulation of cell size|response to organic substance|negative regulation of transcription by competitive promoter binding|pituitary gland development|cell differentiation|mammary gland development|positive regulation of transforming growth factor beta3 production|secretory granule organization|response to glucagon|positive regulation of multicellular organism growth|response to drug|regulation of circadian rhythm|regulation of apoptotic process|positive regulation of fat cell differentiation|positive regulation of osteoclast differentiation|positive regulation of transcription, DNA-templated|positive regulation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hormone secretion|positive regulation of lipid biosynthetic process|rhythmic process|protein stabilization|lung epithelium development|lung saccule development|Type I pneumocyte differentiation|cellular response to zinc ion|cellular response to growth factor stimulus|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|enzyme binding|histone acetyltransferase binding|cAMP response element binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.3,1.25,10,1,1.89,0.2,1.63,1.63,0.547,0,0,-0.7,1.9
ENSMUSG00000004446,BID,BH3 interacting domain death agonist,intracellular|cell|cytoplasm|mitochondrion|mitochondrion|mitochondrion|cytosol|cytosol|membrane|integral component of mitochondrial membrane|extracellular vesicular exosome|,release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|protein targeting to mitochondrion|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|apoptotic mitochondrial changes|regulation of protein oligomerization|positive regulation of protein oligomerization|positive regulation of protein homooligomerization|positive regulation of protein homooligomerization|regulation of cell proliferation|signal transduction in response to DNA damage|regulation of apoptotic process|positive regulation of apoptotic process|protein homooligomerization|establishment of protein localization to membrane|positive regulation of release of cytochrome c from mitochondria|positive regulation of release of cytochrome c from mitochondria|extrinsic apoptotic signaling pathway|hepatocyte apoptotic process|mitochondrial outer membrane permeabilization|regulation of mitochondrial membrane permeability involved in apoptotic process|regulation of G1/S transition of mitotic cell cycle|positive regulation of extrinsic apoptotic signaling pathway|,protein binding|ubiquitin protein ligase binding|,10,0,0,10,-0.3,3.38,-0.2,1.63,-1.63,0.547,0,0,-1.5,1
ENSMUSG00000019861,GOPC,golgi associated PDZ and coiled-coil motif containing,cytoplasm|Golgi apparatus|Golgi apparatus|plasma membrane|membrane|cell junction|trans-Golgi network transport vesicle|cell projection|protein complex|synapse|postsynaptic membrane|,transport|autophagy|spermatid nucleus differentiation|protein transport|regulation of catalytic activity|protein homooligomerization|,small GTPase regulator activity|frizzled binding|protein binding|protein C-terminus binding|protein homodimerization activity|ion channel binding|,10,0.4,2.79,10,0,0,0.2,1.61,1.61,0.55,0,0,-0.9,1.5
ENSMUSG00000025384,2310003H01RIK,RIKEN cDNA 2310003H01 gene,nucleus|cytoplasm|Fanconi anaemia nuclear complex|intermediate filament cytoskeleton|,DNA repair|cellular response to DNA damage stimulus|biological_process|,molecular_function|DNA binding|,10,0.1,0.428,10,0.2,1.32,0.2,1.61,1.61,0.55,0,0,-0.8,1.6
ENSMUSG00000070808,GLTSCR1,glioma tumor suppressor candidate region gene 1,cellular_component|,biological_process|,molecular_function|,10,0.4,1.4,10,0.2,0.741,0.3,1.6,1.6,0.551,0,0,-0.8,1.7
ENSMUSG00000041565,L3MBTL4,l(3)mbt-like 4 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|",molecular_function|sequence-specific DNA binding transcription factor activity|zinc ion binding|,10,-0.1,0.00181,10,0.3,3.07,0.2,1.59,1.59,0.552,0,0,-0.9,1.6
ENSMUSG00000026840,LAMC3,laminin gamma 3,extracellular region|proteinaceous extracellular matrix|basement membrane|,cell morphogenesis involved in differentiation|cell adhesion|visual perception|astrocyte development|retina development in camera-type eye|,None,10,-0.1,0.247,10,-0.3,1.97,-0.2,1.59,-1.59,0.552,0,0,-1.6,0.7
ENSMUSG00000038760,TRHR,thyrotropin releasing hormone receptor,plasma membrane|cell surface|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of protein homodimerization activity|,signal transducer activity|G-protein coupled receptor activity|thyrotropin-releasing hormone receptor activity|protein homodimerization activity|,10,0.2,0.774,10,0.2,0.94,0.2,1.58,1.58,0.554,0,0,-1.1,1.4
ENSMUSG00000021025,NFKBIA,"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha",nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytosol|plasma membrane|protein complex|,"protein import into nucleus, translocation|cytoplasmic sequestering of NF-kappaB|regulation of gene expression|negative regulation of macrophage derived foam cell differentiation|positive regulation of cholesterol efflux|negative regulation of lipid storage|lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|positive regulation of cellular protein metabolic process|response to muramyl dipeptide|response to lipopolysaccharide|toll-like receptor 4 signaling pathway|regulation of cell proliferation|cytoplasmic sequestering of transcription factor|response to exogenous dsRNA|negative regulation of myeloid cell differentiation|negative regulation of Notch signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|nucleotide-binding oligomerization domain containing 1 signaling pathway|nucleotide-binding oligomerization domain containing 2 signaling pathway|",protein binding|nuclear localization sequence binding|enzyme binding|heat shock protein binding|ubiquitin protein ligase binding|protein complex binding|identical protein binding|NF-kappaB binding|,10,-0.2,1.23,10,-0.7,0.572,-0.2,1.57,-1.57,0.555,0,0,-1.8,0.9
ENSMUSG00000038894,IRS2,insulin receptor substrate 2,cytoplasm|cytosol|plasma membrane|,positive regulation of mesenchymal cell proliferation|negative regulation of B cell apoptotic process|signal transduction|brain development|cell proliferation|positive regulation of cell proliferation|insulin receptor signaling pathway|insulin receptor signaling pathway|response to glucose|negative regulation of plasma membrane long-chain fatty acid transport|positive regulation of glucose metabolic process|positive regulation of cell migration|mammary gland development|positive regulation of B cell proliferation|positive regulation of fatty acid beta-oxidation|positive regulation of insulin secretion|cellular response to insulin stimulus|cellular response to insulin stimulus|negative regulation of kinase activity|positive regulation of glycogen biosynthetic process|positive regulation of glucose import|,signal transducer activity|insulin receptor binding|protein binding|protein kinase binding|protein phosphatase binding|protein domain specific binding|phosphatidylinositol 3-kinase binding|phosphatidylinositol 3-kinase binding|14-3-3 protein binding|,10,0.6,1.1,10,-1.1,4.79,-1.1,1.56,-1.56,0.556,0,0,-2,1.3
ENSMUSG00000046207,PIK3R6,"phosphoinositide-3-kinase, regulatory subunit 6","cytoplasm|1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex|membrane|",angiogenesis|G-protein coupled receptor signaling pathway|positive regulation of MAP kinase activity|regulation of phosphatidylinositol 3-kinase activity|positive regulation of angiogenesis|,"phosphatidylinositol-4,5-bisphosphate 3-kinase activity|1-phosphatidylinositol-3-kinase regulator activity|",10,0.1,0.152,10,0.2,1.87,0.2,1.56,1.56,0.556,0,0,-0.8,1.6
ENSMUSG00000031446,CUL4A,cullin 4A,cullin-RING ubiquitin ligase complex|Cul4A-RING E3 ubiquitin ligase complex|Cul4-RING E3 ubiquitin ligase complex|,DNA repair|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|positive regulation of cell proliferation|viral process|hemopoiesis|negative regulation of granulocyte differentiation|somatic stem cell maintenance|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of protein catabolic process|regulation of protein metabolic process|positive regulation of G1/S transition of mitotic cell cycle|regulation of DNA damage checkpoint|regulation of nucleotide-excision repair|,protein binding|ubiquitin protein ligase binding|,10,0.3,1.37,10,0.1,0.437,0.2,1.54,1.54,0.559,0,0,-1.1,1.5
ENSMUSG00000044477,ZFAND3,"zinc finger, AN1-type domain 3",cellular_component|,biological_process|,DNA binding|zinc ion binding|metal ion binding|,10,0.1,0.352,10,0.2,1.51,0.2,1.54,1.54,0.559,0,0,-0.8,1.6
ENSMUSG00000036599,CHST12,carbohydrate sulfotransferase 12,Golgi apparatus|membrane|membrane|integral component of membrane|,carbohydrate metabolic process|carbohydrate biosynthetic process|chondroitin sulfate biosynthetic process|dermatan sulfate biosynthetic process|,sulfotransferase activity|transferase activity|chondroitin 4-sulfotransferase activity|,10,0.2,1.22,10,0.1,0.448,0.2,1.53,1.53,0.56,0,0,-0.7,1.7
ENSMUSG00000032086,BACE1,beta-site APP cleaving enzyme 1,endosome|late endosome|multivesicular body|endoplasmic reticulum|Golgi apparatus|trans-Golgi network|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|cytoplasmic vesicle|,proteolysis|proteolysis|beta-amyloid metabolic process|,beta-amyloid binding|endopeptidase activity|aspartic-type endopeptidase activity|protein binding|peptidase activity|hydrolase activity|enzyme binding|,10,0.2,1.01,10,0.4,0.836,0.3,1.53,1.53,0.56,0,0,-1.6,1.5
ENSMUSG00000079597,GM5483,predicted gene 5483,None,None,None,2,0,0,2,0.6,2.35,0.6,1.52,1.52,0.561,0,0,-1.4,2
ENSMUSG00000002393,NR2F6,"nuclear receptor subfamily 2, group F, member 6",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|entrainment of circadian clock by photoperiod|steroid hormone mediated signaling pathway|neuron development|detection of temperature stimulus involved in sensory perception of pain|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.2,0.943,10,-0.2,0.687,-0.2,1.51,-1.51,0.563,0,0,-1.5,1.1
ENSMUSG00000015468,NOTCH4,notch 4,nucleus|plasma membrane|cell surface|membrane|integral component of membrane|,"patterning of blood vessels|morphogenesis of a branching structure|endothelial cell morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|Notch signaling pathway|multicellular organismal development|embryo development|cell differentiation|mammary gland development|endothelial cell differentiation|negative regulation of endothelial cell differentiation|regulation of developmental process|",calcium ion binding|protein binding|,10,0.2,0.781,10,0.3,1.17,0.3,1.51,1.51,0.563,0,0,-0.5,1.8
ENSMUSG00000030324,RHO,rhodopsin,photoreceptor outer segment|photoreceptor outer segment|photoreceptor inner segment|photoreceptor inner segment|Golgi apparatus|plasma membrane|cell-cell junction|membrane|integral component of membrane|rough endoplasmic reticulum membrane|photoreceptor outer segment membrane|photoreceptor inner segment membrane|,"protein phosphorylation|signal transduction|G-protein coupled receptor signaling pathway|visual perception|phototransduction|response to light stimulus|detection of light stimulus|red, far-red light phototransduction|rhodopsin mediated signaling pathway|protein-chromophore linkage|response to stimulus|sensory perception of light stimulus|retina development in camera-type eye|cellular response to light stimulus|",signal transducer activity|G-protein coupled receptor activity|protein binding|photoreceptor activity|retinal binding|spectrin binding|metal ion binding|,10,0,0,10,-0.4,3.66,-0.3,1.51,-1.51,0.563,0,0,-1.6,0.9
ENSMUSG00000032356,RASGRF1,RAS protein-specific guanine nucleotide-releasing factor 1,intracellular|cytosol|growth cone|,small GTPase mediated signal transduction|cell proliferation|neuron projection development|positive regulation of Ras GTPase activity|activation of Rac GTPase activity|regulation of Rac protein signal transduction|regulation of Rho protein signal transduction|intracellular signal transduction|regulation of Ras protein signal transduction|positive regulation of Ras protein signal transduction|regulation of synaptic plasticity|regulation of neuronal synaptic plasticity|regulation of small GTPase mediated signal transduction|regulation of N-methyl-D-aspartate selective glutamate receptor activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|protein C-terminus binding|protein kinase binding|glutamate receptor binding|,10,0.2,0.75,10,0.2,0.873,0.2,1.5,1.5,0.564,0,0,-0.9,1.6
ENSMUSG00000025422,AGAP2,"ArfGAP with GTPase domain, ankyrin repeat and PH domain 2",intracellular|nucleus|nucleolus|cytoplasm|mitochondrion|endosome|membrane|,GTP catabolic process|small GTPase mediated signal transduction|positive regulation of phosphatidylinositol 3-kinase signaling|endosomal transport|actin cytoskeleton organization|regulation of ARF GTPase activity|positive regulation of mammary gland epithelial cell proliferation|positive regulation of mammary gland epithelial cell proliferation|negative regulation of protein catabolic process|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of GTPase activity|regulation of phosphatidylinositol 3-kinase activity|positive regulation of protein kinase activity|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JAK-STAT cascade|mammary gland alveolus development|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,nucleotide binding|GTPase activity|GTPase activator activity|protein binding|ATP binding|GTP binding|ARF GTPase activator activity|zinc ion binding|protein kinase binding|protein kinase activator activity|phosphatidylinositol 3-kinase regulator activity|metal ion binding|,10,0.3,2.25,10,0,0,0.3,1.5,1.5,0.564,0,0,-0.8,1.5
ENSMUSG00000020484,XBP1,X-box binding protein 1,nucleus|,"epithelial cell maturation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|endoplasmic reticulum unfolded protein response|exocrine pancreas development|response to drug|glucose homeostasis|positive regulation of transcription from RNA polymerase II promoter|response to electrical stimulus|serotonin secretion, neurotransmission|epithelial cell maturation involved in salivary gland development|positive regulation of endoplasmic reticulum unfolded protein response|positive regulation of proteasomal protein catabolic process|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.5,0.913,10,0.3,0.864,0.4,1.49,1.49,0.566,0,0,-0.9,1.8
ENSMUSG00000029171,PGM1,phosphoglucomutase 1,cytoplasm|cytosol|,carbohydrate metabolic process|glycogen biosynthetic process|glucose metabolic process|galactose catabolic process|,"magnesium ion binding|phosphoglucomutase activity|phosphoglucomutase activity|phosphopentomutase activity|isomerase activity|intramolecular transferase activity, phosphotransferases|metal ion binding|",10,0.2,1.25,10,0.1,0.551,0.2,1.49,1.49,0.566,0,0,-1.1,1.5
ENSMUSG00000025316,BANP,BTG3 associated nuclear protein,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|multicellular organismal development|chromatin modification|protein localization to nucleus|negative regulation of protein catabolic process|",p53 binding|DNA binding|protein binding|,10,-0.2,0.544,10,0.4,2.79,0.3,1.49,1.49,0.566,0,0,-1,1.4
ENSMUSG00000021219,RGS6,regulator of G-protein signaling 6,cytoplasm|cytoplasm|Golgi apparatus|heterotrimeric G-protein complex|plasma membrane|membrane|protein complex|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of signal transduction|intracellular signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|positive regulation of neuron differentiation|,signal transducer activity|GTPase activator activity|GTPase activator activity|protein binding|protein domain specific binding|,10,0.3,2.4,10,-0.3,0.127,0.2,1.47,1.47,0.569,0,0,-0.9,1.6
ENSMUSG00000017165,GAST,gastrin,extracellular region|,signal transduction|G-protein coupled receptor signaling pathway|,hormone activity|protein binding|,10,0.2,1.13,10,0.2,0.462,0.2,1.47,1.47,0.569,0,0,-0.9,1.6
ENSMUSG00000020608,SMC6,structural maintenance of chromosomes 6,"chromosome, telomeric region|intracellular|nucleus|chromosome|nucleolus|PML body|Smc5-Smc6 complex|",telomere maintenance via recombination|double-strand break repair via homologous recombination|DNA repair|DNA recombination|cellular response to DNA damage stimulus|cellular senescence|,nucleotide binding|molecular_function|ATP binding|,9,-1.5,3.31,9,0.3,2,-1.4,1.47,-1.47,0.569,0,0,-2.9,0.7
ENSMUSG00000038508,GDF15,growth differentiation factor 15,extracellular region|extracellular space|extracellular vesicular exosome|,None,cytokine activity|growth factor activity|,10,-0.9,4.65,10,0,0,-0.9,1.46,-1.46,0.57,0,0,-2,0.3
ENSMUSG00000033544,ANGPTL1,angiopoietin-like 1,extracellular region|extracellular space|extracellular vesicular exosome|,transmembrane receptor protein tyrosine kinase signaling pathway|,receptor binding|,10,-0.2,0.818,10,-0.2,0.759,-0.2,1.45,-1.45,0.571,0,0,-1.4,1.2
ENSMUSG00000034959,5031414D18RIK,RIKEN cDNA 5031414D18 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.139,10,-0.2,1.72,-0.2,1.45,-1.45,0.571,0,0,-1.4,1.1
ENSMUSG00000027869,HSD3B6,"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6",mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|endoplasmic reticulum|membrane|integral component of membrane|,steroid biosynthetic process|metabolic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|catalytic activity|3-beta-hydroxy-delta5-steroid dehydrogenase activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|steroid delta-isomerase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|isomerase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,-0.2,1.04,10,-0.2,0.498,-0.2,1.43,-1.43,0.574,0,0,-1.1,1.7
ENSMUSG00000005824,TNFSF14,"tumor necrosis factor (ligand) superfamily, member 14",extracellular region|extracellular space|plasma membrane|membrane|integral component of membrane|,immune response|release of cytoplasmic sequestered NF-kappaB|positive regulation of T cell chemotaxis|T cell costimulation|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|,receptor binding|cytokine activity|tumor necrosis factor receptor binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|,10,0.1,0.383,10,0.2,1.27,0.2,1.42,1.42,0.575,0,0,-1,1.6
ENSMUSG00000060475,WTAP,Wilms tumour 1-associating protein,nucleus|nucleus|nucleoplasm|nuclear speck|nuclear membrane|MIS complex|,"regulation of alternative mRNA splicing, via spliceosome|mRNA processing|cell cycle|multicellular organismal development|RNA splicing|mRNA methylation|",None,10,0.4,2.54,10,-0.1,0.25,-0.2,1.4,-1.4,0.578,0,0,-1.4,1.4
ENSMUSG00000079566,SPIN2D,"spindlin family, member 2D",cellular_component|,biological_process|,molecular_function|,6,-1.1,3.06,6,0.3,0.944,-1,1.4,-1.4,0.578,0,0,-2,1
ENSMUSG00000040596,POGK,pogo transposable element with KRAB domain,cellular_component|intracellular|nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|biological_process|",nucleic acid binding|DNA binding|,10,0.5,2.25,10,0.2,0.219,0.3,1.4,1.4,0.578,0,0,-1.2,1.6
ENSMUSG00000030051,APLF,aprataxin and PNKP like factor,nucleus|cytoplasm|site of double-strand break|,"single strand break repair|DNA catabolic process, endonucleolytic|DNA repair|double-strand break repair|double-strand break repair|cellular response to DNA damage stimulus|regulation of isotype switching|positive regulation of DNA ligation|nucleic acid phosphodiester bond hydrolysis|",nucleotide binding|DNA-(apurinic or apyrimidinic site) lyase activity|endodeoxyribonuclease activity|3'-5' exonuclease activity|lyase activity|metal ion binding|,10,0.2,0.729,10,-0.5,2.89,-0.5,1.4,-1.4,0.578,0,0,-1.6,1
ENSMUSG00000038909,KAT7,K(lysine) acetyltransferase 7,histone acetyltransferase complex|nucleus|nucleoplasm|cytoplasm|,"DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H3 acetylation|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K12 acetylation|","sequence-specific DNA binding transcription factor activity|histone acetyltransferase activity|zinc ion binding|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|metal ion binding|",10,0.3,2.1,10,-0.4,3.06,-0.3,1.38,-1.38,0.581,0,0,-1.5,1.1
ENSMUSG00000032854,UGT8A,UDP galactosyltransferase 8A,intracellular|cell|membrane|integral component of membrane|,protein localization to paranode region of axon|lipid metabolic process|sphingolipid metabolic process|cytoskeleton organization|axon cargo transport|metabolic process|glycolipid biosynthetic process|paranodal junction assembly|myelination|neuron projection morphogenesis|,"2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity|ceramide glucosyltransferase activity|UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,0.2,1.88,10,0.1,0.0143,0.2,1.38,1.38,0.581,0,0,-0.8,1.7
ENSMUSG00000042642,FLAD1,"RFad1, flavin adenine dinucleotide synthetase, homolog (yeast)",cellular_component|cytoplasm|,FAD biosynthetic process|Mo-molybdopterin cofactor biosynthetic process|metabolic process|,nucleotide binding|catalytic activity|FMN adenylyltransferase activity|ATP binding|transferase activity|nucleotidyltransferase activity|,10,0.1,0.784,10,0.2,0.742,0.2,1.38,1.38,0.581,0,0,-0.7,1.7
ENSMUSG00000027871,HSD3B1,"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1",mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|,steroid biosynthetic process|metabolic process|oxidation-reduction process|,"catalytic activity|3-beta-hydroxy-delta5-steroid dehydrogenase activity|steroid delta-isomerase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|isomerase activity|",10,0.2,0.748,10,0.1,0.858,0.2,1.38,1.38,0.581,0,0,-1,1.6
ENSMUSG00000012483,RPA3,replication protein A3,nucleus|DNA replication factor A complex|,double-strand break repair via homologous recombination|DNA replication|DNA repair|base-excision repair|nucleotide-excision repair|mismatch repair|DNA recombination|cellular response to DNA damage stimulus|regulation of mitotic cell cycle|regulation of cell proliferation|,DNA binding|damaged DNA binding|single-stranded DNA binding|,8,0.2,1.14,8,-0.2,0.465,0.2,1.37,1.37,0.582,0,0,-1.2,1.6
ENSMUSG00000056215,LRGUK,leucine-rich repeats and guanylate kinase domain containing,nucleus|cytoplasm|,biological_process|phosphorylation|,nucleotide binding|molecular_function|ATP binding|kinase activity|transferase activity|,9,-0.2,0.18,9,-0.5,2.07,-0.4,1.37,-1.37,0.582,0,0,-1.9,0.5
ENSMUSG00000018377,VEZF1,vascular endothelial zinc finger 1,nucleus|,angiogenesis|endothelial cell development|,None,10,0,0,10,-0.8,3.34,-0.3,1.37,-1.37,0.582,0,0,-2,0.3
ENSMUSG00000042508,DMTF1,cyclin D binding myb-like transcription factor 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|",DNA binding|chromatin binding|,10,-0.2,0.48,10,-0.2,0.991,-0.2,1.36,-1.36,0.583,0,0,-1.5,1.1
ENSMUSG00000031097,TNNI2,"troponin I, skeletal, fast 2",nucleus|troponin complex|,"skeletal muscle contraction|regulation of muscle contraction|positive regulation of transcription, DNA-templated|",actin binding|troponin T binding|metal ion binding|,10,0.3,1.39,10,0.1,0.23,0.2,1.36,1.36,0.583,0,0,-0.9,1.7
ENSMUSG00000022548,APOD,apolipoprotein D,extracellular region|extracellular space|intracellular|cytoplasm|endoplasmic reticulum|cytosolic ribosome|dendrite|neuronal cell body|perinuclear region of cytoplasm|extracellular vesicular exosome|,response to reactive oxygen species|response to reactive oxygen species|glucose metabolic process|lipid metabolic process|transport|negative regulation of platelet-derived growth factor receptor signaling pathway|negative regulation of protein import into nucleus|negative regulation of smooth muscle cell proliferation|negative regulation of focal adhesion assembly|negative regulation of lipoprotein lipid oxidation|negative regulation of lipoprotein lipid oxidation|negative regulation of monocyte chemotactic protein-1 production|negative regulation of cytokine production involved in inflammatory response|negative regulation of smooth muscle cell-matrix adhesion|negative regulation of T cell migration|,transporter activity|lipid binding|cholesterol binding|small molecule binding|,10,-0.2,1.26,10,-0.1,0.307,-0.2,1.36,-1.36,0.583,0,0,-1.6,0.9
ENSMUSG00000027776,IL12A,interleukin 12a,extracellular region|extracellular space|extracellular space|cytoplasm|interleukin-12 complex|interleukin-12 complex|interleukin-12 complex|,positive regulation of T cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|immune response|cell cycle arrest|response to UV-B|cell migration|response to lipopolysaccharide|negative regulation of interleukin-17 production|positive regulation of interferon-gamma production|positive regulation of interferon-gamma production|positive regulation of natural killer cell activation|positive regulation of mononuclear cell proliferation|positive regulation of smooth muscle cell apoptotic process|positive regulation of T cell proliferation|positive regulation of tyrosine phosphorylation of Stat4 protein|defense response to protozoan|positive regulation of T cell differentiation|positive regulation of cell adhesion|positive regulation of natural killer cell mediated cytotoxicity|negative regulation of smooth muscle cell proliferation|positive regulation of lymphocyte proliferation|positive regulation of NK T cell activation|extrinsic apoptotic signaling pathway|,cytokine activity|cytokine activity|cytokine activity|interleukin-12 receptor binding|growth factor activity|interleukin-12 beta subunit binding|interleukin-12 beta subunit binding|interleukin-27 binding|protein heterodimerization activity|,10,0.6,3.6,10,0,0,0.5,1.36,1.36,0.583,0,0,-0.5,2
ENSMUSG00000017499,CDC6,cell division cycle 6,spindle pole|nucleus|cytoplasm|cytoplasm|Golgi apparatus|spindle|spindle midzone|,DNA replication|cell cycle|mitotic nuclear division|regulation of mitotic metaphase/anaphase transition|positive regulation of cytokinesis|cell division|positive regulation of chromosome segregation|,nucleotide binding|chromatin binding|ATP binding|kinase binding|,10,-0.6,2.89,10,0.2,1.52,0.2,1.35,1.35,0.585,0,0,-1.7,1.1
ENSMUSG00000015354,PCOLCE2,procollagen C-endopeptidase enhancer 2,extracellular region|extracellular vesicular exosome|,positive regulation of peptidase activity|,collagen binding|heparin binding|peptidase activator activity|,10,-0.2,1.87,10,0.1,0.445,-0.2,1.34,-1.34,0.586,0,0,-1.4,1.2
ENSMUSG00000024403,ATP6V1G2,"ATPase, H+ transporting, lysosomal V1 subunit G2",vacuolar proton-transporting V-type ATPase complex|integral component of synaptic vesicle membrane|,ATP catabolic process|transport|ion transport|proton transport|hydrogen ion transmembrane transport|,"protein binding|hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|ATPase activity|",10,0.1,0.288,10,0.2,1.33,0.2,1.33,1.33,0.588,0,0,-0.9,1.6
ENSMUSG00000030579,TYROBP,TYRO protein tyrosine kinase binding protein,cell surface|membrane|integral component of membrane|,macrophage activation involved in immune response|neutrophil activation involved in immune response|integrin-mediated signaling pathway|phosphorylation|regulation of osteoclast development|,receptor binding|protein binding|kinase activity|transferase activity|identical protein binding|,10,0.2,1.06,10,0.1,0.452,0.2,1.33,1.33,0.588,0,0,-0.7,1.7
ENSMUSG00000033762,RECQL4,RecQ protein-like 4,nucleus|cytoplasm|membrane|,DNA strand renaturation|skeletal system development|ATP catabolic process|DNA replication|DNA recombination|positive regulation of cell proliferation|DNA duplex unwinding|pigmentation|negative regulation of sister chromatid cohesion|skeletal system morphogenesis|,nucleotide binding|bubble DNA binding|nucleic acid binding|helicase activity|ATP binding|ATP-dependent helicase activity|zinc ion binding|hydrolase activity|annealing helicase activity|ATP-dependent 3'-5' DNA helicase activity|metal ion binding|,10,0.3,1.66,10,0.1,0.15,0.2,1.32,1.32,0.589,0,0,-1,1.6
ENSMUSG00000030339,LTBR,lymphotoxin B receptor,membrane|integral component of membrane|,apoptotic process|myeloid dendritic cell differentiation|positive regulation of JNK cascade|lymph node development|positive regulation of extrinsic apoptotic signaling pathway|,protein binding|ubiquitin protein ligase binding|identical protein binding|,10,-0.2,1.31,10,0.4,1.31,-0.2,1.3,-1.3,0.592,0,0,-1.5,1.4
ENSMUSG00000030417,PDCD5,programmed cell death 5,nucleus|cytoplasm|extracellular vesicular exosome|,apoptotic process|positive regulation of apoptotic process|,molecular_function|,10,0.6,3.14,10,0.1,0.092,0.1,1.3,1.3,0.592,0,0,-0.3,1.9
ENSMUSG00000037705,TECTA,tectorin alpha,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,cell-matrix adhesion|sensory perception of sound|,extracellular matrix structural constituent|extracellular matrix structural constituent|protein binding|,10,0.2,0.776,10,0.2,0.637,0.2,1.3,1.3,0.592,0,0,-1.1,1.4
ENSMUSG00000020383,IL13,interleukin 13,extracellular region|extracellular space|extracellular space|cytoplasm|external side of plasma membrane|,microglial cell activation|positive regulation of immunoglobulin production|immune response|regulation of proton transport|positive regulation of B cell proliferation|positive regulation of connective tissue growth factor production|negative regulation of NAD(P)H oxidase activity|response to nicotine|positive regulation of tyrosine phosphorylation of Stat6 protein|positive regulation of macrophage activation|positive regulation of ion transport|positive regulation of smooth muscle cell proliferation|positive regulation of protein secretion|positive regulation of release of sequestered calcium ion into cytosol|cellular response to cytokine stimulus|negative regulation of transforming growth factor beta production|negative regulation of neuron death|positive regulation of pancreatic stellate cell proliferation|,cytokine activity|cytokine receptor binding|interleukin-13 receptor binding|,10,0.1,0.332,10,0.3,1.36,0.2,1.29,1.29,0.594,0,0,-0.7,1.7
ENSMUSG00000027398,IL1B,interleukin 1 beta,extracellular region|extracellular space|extracellular space|intracellular|secretory granule|vesicle|,"negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|activation of MAPK activity|fever generation|positive regulation of protein phosphorylation|inflammatory response|immune response|positive regulation of cytosolic calcium ion concentration|aging|memory|negative regulation of cell proliferation|response to carbohydrate|positive regulation vascular endothelial growth factor production|positive regulation vascular endothelial growth factor production|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|negative regulation of glucose transport|positive regulation of cell death|negative regulation of glutamate secretion|cytokine-mediated signaling pathway|hyaluronan biosynthetic process|neutrophil chemotaxis|sequestering of triglyceride|positive regulation of fever generation|lipopolysaccharide-mediated signaling pathway|positive regulation of prostaglandin secretion|response to lipopolysaccharide|response to lipopolysaccharide|interleukin-1 beta production|positive regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of interferon-gamma production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-8 production|positive regulation of stress-activated MAPK cascade|positive regulation of immature T cell proliferation in thymus|response to ATP|response to ATP|positive regulation of heterotypic cell-cell adhesion|social behavior|ectopic germ cell programmed cell death|positive regulation of myosin light chain kinase activity|cellular response to drug|positive regulation of T cell proliferation|positive regulation of NF-kappaB import into nucleus|positive regulation of apoptotic process|regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of MAP kinase activity|protein kinase B signaling|positive regulation of JUN kinase activity|positive regulation of chemokine biosynthetic process|positive regulation of interleukin-2 biosynthetic process|positive regulation of interleukin-6 biosynthetic process|positive regulation of nitric oxide biosynthetic process|negative regulation of neuron differentiation|positive regulation of glial cell differentiation|positive regulation of angiogenesis|negative regulation of lipid metabolic process|positive regulation of mitosis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|positive regulation of JNK cascade|positive regulation of JNK cascade|negative regulation of insulin receptor signaling pathway|positive regulation of astrocyte differentiation|negative regulation of neurogenesis|regulation of insulin secretion|leukocyte migration|negative regulation of lipid catabolic process|positive regulation of lipid catabolic process|positive regulation of membrane protein ectodomain proteolysis|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of cell division|positive regulation of calcidiol 1-monooxygenase activity|negative regulation of adiponectin secretion|positive regulation of ERK1 and ERK2 cascade|monocyte aggregation|cellular response to organic substance|cellular response to organic cyclic compound|positive regulation of monocyte chemotactic protein-1 production|positive regulation of neutrophil chemotaxis|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of branching morphogenesis of a nerve|negative regulation of neural precursor cell proliferation|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|",receptor binding|cytokine activity|cytokine activity|interleukin-1 receptor binding|protein domain specific binding|,10,0,0,10,0.2,1.66,0.2,1.29,1.29,0.594,0,0,-1,1.7
ENSMUSG00000027602,MAP1LC3A,microtubule-associated protein 1 light chain 3 alpha,autophagic vacuole membrane|autophagic vacuole membrane|cytoplasm|late endosome|autophagic vacuole|autophagic vacuole|cytosol|cytoskeleton|microtubule|microtubule cytoskeleton|membrane|organelle membrane|cytoplasmic vesicle|,autophagic vacuole assembly|mitochondrion degradation|autophagy|,protein binding|phospholipid binding|microtubule binding|phosphatidylethanolamine binding|,10,-0.4,1.49,10,-0.1,0.392,-0.2,1.27,-1.27,0.597,0,0,-1.4,1.6
ENSMUSG00000064293,CNTN4,contactin 4,extracellular region|plasma membrane|membrane|anchored component of membrane|,cell adhesion|nervous system development|neuron projection development|negative regulation of neuron differentiation|,None,9,-0.5,2.4,9,0.1,0.168,-0.4,1.27,-1.27,0.597,0,0,-1.8,0.8
ENSMUSG00000044340,PHLPP1,PH domain and leucine rich repeat protein phosphatase 1,nucleus|nucleoplasm|cytoplasm|membrane|nuclear membrane|,protein dephosphorylation|apoptotic process|entrainment of circadian clock|negative regulation of protein kinase B signaling|negative regulation of protein kinase C signaling|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,0.1,0.0434,10,0.2,1.35,0.1,1.27,1.27,0.597,0,0,-0.7,1.9
ENSMUSG00000019920,LIMS1,LIM and senescent cell antigen-like domains 1,plasma membrane|focal adhesion|focal adhesion|focal adhesion|membrane|cell junction|protein complex|perinuclear region of cytoplasm|,"cell-matrix adhesion|establishment or maintenance of cell polarity|single organismal cell-cell adhesion|chordate embryonic development|negative regulation of apoptotic process|cell-cell junction organization|negative regulation of transcription, DNA-templated|negative regulation of epithelial cell proliferation|protein heterooligomerization|negative regulation of neural precursor cell proliferation|negative regulation of hepatocyte proliferation|positive regulation of integrin-mediated signaling pathway|",protein binding|zinc ion binding|metal ion binding|,10,0.7,3.29,10,0.1,0.145,0.2,1.26,1.26,0.599,0,0,-0.3,1.9
ENSMUSG00000003555,CYP17A1,"cytochrome P450, family 17, subfamily a, polypeptide 1",mitochondrion|endoplasmic reticulum|membrane|axon|cell projection|neuronal cell body|neuronal cell body|intracellular membrane-bounded organelle|,steroid biosynthetic process|glucocorticoid biosynthetic process|steroid metabolic process|hormone biosynthetic process|progesterone metabolic process|oxidation-reduction process|positive regulation of steroid hormone biosynthetic process|,"monooxygenase activity|steroid 17-alpha-monooxygenase activity|steroid 17-alpha-monooxygenase activity|steroid 17-alpha-monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|lyase activity|heme binding|metal ion binding|17-alpha-hydroxyprogesterone aldolase activity|",10,0.3,1.84,10,-0.1,0.13,0.2,1.25,1.25,0.6,0,0,-0.8,1.6
ENSMUSG00000019467,ARHGEF25,Rho guanine nucleotide exchange factor (GEF) 25,cytoplasm|plasma membrane|membrane|myofibril|,regulation of Rho protein signal transduction|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|,10,0.2,0.62,10,0.2,0.735,0.2,1.25,1.25,0.6,0,0,-0.9,1.6
ENSMUSG00000022015,TNFSF11,"tumor necrosis factor (ligand) superfamily, member 11",extracellular region|extracellular space|intracellular|cytoplasm|plasma membrane|membrane|integral component of membrane|,ossification|osteoclast proliferation|monocyte chemotaxis|immune response|activation of JUN kinase activity|multicellular organismal development|organ morphogenesis|cytokine-mediated signaling pathway|cell differentiation|osteoclast differentiation|osteoclast differentiation|osteoclast differentiation|osteoclast differentiation|tumor necrosis factor-mediated signaling pathway|mammary gland epithelial cell proliferation|positive regulation of homotypic cell-cell adhesion|positive regulation of phosphorylation|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of MAP kinase activity|bone resorption|regulation of osteoclast differentiation|positive regulation of osteoclast differentiation|positive regulation of osteoclast differentiation|positive regulation of osteoclast differentiation|positive regulation of bone resorption|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|lymph node development|positive regulation of T cell activation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein homooligomerization|positive regulation of corticotropin-releasing hormone secretion|positive regulation of protein kinase B signaling|calcium ion homeostasis|mammary gland alveolus development|ERK1 and ERK2 cascade|positive regulation of fever generation by positive regulation of prostaglandin secretion|TNFSF11-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling|positive regulation of intracellular signal transduction|positive regulation of osteoclast development|,cytokine activity|tumor necrosis factor receptor binding|protein binding|tumor necrosis factor receptor superfamily binding|,10,0,0,10,-0.5,3,-0.2,1.25,-1.25,0.6,0,0,-1.8,0.5
ENSMUSG00000031502,COL4A1,"collagen, type IV, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type IV trimer|collagen type IV trimer|basement membrane|,angiogenesis|patterning of blood vessels|brain development|neuromuscular junction development|blood vessel morphogenesis|retinal blood vessel morphogenesis|renal tubule morphogenesis|cellular response to amino acid stimulus|basement membrane organization|,extracellular matrix structural constituent|platelet-derived growth factor binding|,10,0.3,1.58,10,-0.6,3.43,-0.3,1.24,-1.24,0.601,0,0,-1.8,1.1
ENSMUSG00000040732,ERG,avian erythroblastosis virus E-26 (v-ets) oncogene related,nucleus|cytoplasm|ribonucleoprotein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.7,3.89,10,0.1,0.0549,-0.4,1.24,-1.24,0.601,0,0,-2,0.4
ENSMUSG00000074129,RPL13A,ribosomal protein L13A,nucleus|ribosome|large ribosomal subunit|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|ribonucleoprotein complex|GAIT complex|GAIT complex|,translation|regulation of translation|negative regulation of translation|negative regulation of translation|response to lipopolysaccharide|regulation of homeostatic process|macrophage chemotaxis|lung morphogenesis|cellular response to interferon-gamma|cellular response to interferon-gamma|negative regulation of formation of translation preinitiation complex|,mRNA binding|structural constituent of ribosome|poly(A) RNA binding|,9,-0.1,0.0849,9,1.1,4.19,1.1,1.23,1.23,0.603,0,0,-0.4,2
ENSMUSG00000001506,COL1A1,"collagen, type I, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen trimer|collagen type I trimer|collagen type I trimer|collagen type I trimer|extracellular space|cytoplasm|endoplasmic reticulum|Golgi apparatus|secretory granule|extracellular matrix|extracellular matrix|,"skeletal system development|skeletal system development|blood vessel development|blood vessel development|intramembranous ossification|endochondral ossification|visual perception|sensory perception of sound|positive regulation of epithelial to mesenchymal transition|negative regulation of cell-substrate adhesion|protein transport|collagen fibril organization|positive regulation of cell migration|collagen biosynthetic process|protein localization to nucleus|tooth mineralization|wound healing|skin development|skin morphogenesis|positive regulation of transcription, DNA-templated|skeletal system morphogenesis|embryonic skeletal system development|face morphogenesis|bone trabecula formation|cartilage development involved in endochondral bone morphogenesis|protein heterotrimerization|cellular response to amino acid stimulus|positive regulation of canonical Wnt signaling pathway|",extracellular matrix structural constituent|protein binding|identical protein binding|metal ion binding|platelet-derived growth factor binding|,10,0.2,1.09,10,0.2,0.235,0.2,1.23,1.23,0.603,0,0,-1.3,1.5
ENSMUSG00000005547,CYP2A5,"cytochrome P450, family 2, subfamily a, polypeptide 5",cytoplasmic microtubule|,heme metabolic process|oxidation-reduction process|cellular response to cadmium ion|,coumarin 7-hydroxylase activity|enzyme binding|heme binding|,10,-0.2,0.92,10,0.4,1.66,0.3,1.23,1.23,0.603,0,0,-1.1,1.7
ENSMUSG00000036478,BTG1,"B cell translocation gene 1, anti-proliferative",nucleus|cytoplasm|,protein methylation|negative regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of catalytic activity|positive regulation of endothelial cell differentiation|positive regulation of myoblast differentiation|positive regulation of angiogenesis|positive regulation of fibroblast apoptotic process|,protein binding|enzyme binding|,10,-0.1,0.738,10,-0.1,0.589,-0.1,1.22,-1.22,0.605,0,0,-1.7,0.9
ENSMUSG00000021318,GLI3,GLI-Kruppel family member GLI3,nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cilium|cilium|mediator complex|nuclear speck|transcriptional repressor complex|cell projection|primary cilium|primary cilium|,"negative regulation of transcription from RNA polymerase II promoter|metanephros development|branching involved in ureteric bud morphogenesis|in utero embryonic development|kidney development|positive regulation of neuroblast proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|smoothened signaling pathway|pattern specification process|axon guidance|central nervous system development|central nervous system development|brain development|hindgut morphogenesis|heart development|negative regulation of cell proliferation|negative regulation of cell proliferation|anterior/posterior pattern specification|dorsal/ventral pattern formation|proximal/distal pattern formation|proximal/distal pattern formation|regulation of gene expression|protein processing|spinal cord dorsal/ventral patterning|spinal cord motor neuron differentiation|telencephalon development|pallium development|subpallium development|optic nerve morphogenesis|hippocampus development|smoothened signaling pathway involved in ventral spinal cord interneuron specification|smoothened signaling pathway involved in spinal cord motor neuron cell fate specification|forebrain dorsal/ventral pattern formation|cerebral cortex radial glia guided migration|forebrain radial glial cell differentiation|neural tube development|lateral ganglionic eminence cell proliferation|melanocyte differentiation|lung development|lung development|embryonic limb morphogenesis|embryonic limb morphogenesis|mammary gland development|forebrain development|positive regulation of chondrocyte differentiation|T cell differentiation in thymus|limb morphogenesis|limb morphogenesis|tube development|regulation of cell proliferation|positive regulation of protein import into nucleus|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|embryonic digit morphogenesis|regulation of apoptotic process|camera-type eye development|negative regulation of apoptotic process|tongue development|negative thymic T cell selection|negative thymic T cell selection|regulation of cell differentiation|negative regulation of cell differentiation|negative regulation of neuron differentiation|positive regulation of osteoblast differentiation|positive regulation of osteoblast differentiation|negative regulation of smoothened signaling pathway|negative regulation of smoothened signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T cell differentiation|embryonic digestive tract morphogenesis|embryonic digestive tract development|developmental growth|camera-type eye morphogenesis|embryonic morphogenesis|anatomical structure formation involved in morphogenesis|neuron fate commitment|embryonic skeletal system morphogenesis|oligodendrocyte differentiation|branching morphogenesis of an epithelial tube|inner ear development|anatomical structure development|palate development|limb development|limb development|frontal suture morphogenesis|lambdoid suture morphogenesis|sagittal suture morphogenesis|mammary gland specification|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|artery development|anterior semicircular canal development|lateral semicircular canal development|cell differentiation involved in kidney development|thymocyte apoptotic process|thymocyte apoptotic process|negative regulation of canonical Wnt signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|beta-catenin binding|histone acetyltransferase binding|histone deacetylase binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,-0.4,2.62,-0.3,1.22,-1.22,0.605,0,0,-1.7,0.6
ENSMUSG00000026349,CCNT2,cyclin T2,nucleus|,None,None,10,0.7,3.96,10,0,0,0.7,1.22,1.22,0.605,0,0,-0.2,2
ENSMUSG00000005575,UBE2M,ubiquitin-conjugating enzyme E2M,extracellular vesicular exosome|,cellular protein modification process|protein ubiquitination|positive regulation of neuron apoptotic process|protein neddylation|,"nucleotide binding|ubiquitin-protein transferase activity|ATP binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|NEDD8 ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,2.27,10,0.8,4.05,0.7,1.22,1.22,0.605,0,0,-1.1,1.9
ENSMUSG00000038567,CYP24A1,"cytochrome P450, family 24, subfamily a, polypeptide 1",mitochondrion|,response to vitamin D|vitamin D metabolic process|vitamin D metabolic process|oxidation-reduction process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|25-hydroxycholecalciferol-24-hydroxylase activity|25-hydroxycholecalciferol-24-hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity|metal ion binding|",10,-0.3,2.03,10,0,0,-0.2,1.21,-1.21,0.606,0,0,-1.6,0.9
ENSMUSG00000032420,NT5E,"5' nucleotidase, ecto",cytoplasm|plasma membrane|plasma membrane|cell surface|membrane|anchored component of membrane|extracellular vesicular exosome|synaptic membrane|,purine nucleotide biosynthetic process|AMP catabolic process|AMP catabolic process|nucleotide catabolic process|dephosphorylation|dephosphorylation|adenosine metabolic process|adenosine biosynthetic process|negative regulation of inflammatory response|,"nucleotide binding|ferrous iron binding|5'-nucleotidase activity|5'-nucleotidase activity|hydrolase activity|hydrolase activity, acting on ester bonds|metal ion binding|",10,-0.1,0.467,10,-0.1,0.811,-0.1,1.18,-1.18,0.611,0,0,-1.7,0.9
ENSMUSG00000026879,GSN,gelsolin,ruffle|extracellular region|extracellular space|cytoplasm|cytosol|cytoskeleton|actin cytoskeleton|lamellipodium|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|blood microparticle|,apoptotic process|actin polymerization or depolymerization|vesicle-mediated transport|cell projection organization|actin filament polymerization|regulation of cell adhesion|phosphatidylinositol-mediated signaling|actin filament severing|actin filament capping|cilium morphogenesis|cellular response to cadmium ion|,actin binding|protein binding|metal ion binding|,10,0.1,0.116,10,0.6,2.42,0.2,1.17,1.17,0.613,0,0,-0.6,1.8
ENSMUSG00000096581,BCL2A1D,B cell leukemia/lymphoma 2 related protein A1d,mitochondrial outer membrane|,intrinsic apoptotic signaling pathway in response to DNA damage|T cell differentiation|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|T cell receptor signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of intrinsic apoptotic signaling pathway|,protein homodimerization activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|protein heterodimerization activity|protein heterodimerization activity|BH domain binding|,10,0.4,1.07,10,0.2,0.574,0.3,1.17,1.17,0.613,0,0,-0.8,1.7
ENSMUSG00000005892,TRH,thyrotropin releasing hormone,extracellular region|nucleus|cytoplasm|plasma membrane|secretory granule|,histamine metabolic process|adult walking behavior|hormone-mediated signaling pathway|negative regulation of glutamate secretion|positive regulation of gamma-aminobutyric acid secretion|positive regulation of insulin secretion|eating behavior|negative regulation of feeding behavior|,hormone activity|neuropeptide hormone activity|protein binding|thyrotropin-releasing hormone activity|thyrotropin-releasing hormone activity|,10,0.3,2.08,10,0,0,0.2,1.17,1.17,0.613,0,0,-0.8,1.7
ENSMUSG00000032515,CSRNP1,cysteine-serine-rich nuclear protein 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|apoptotic process|post-embryonic development|positive regulation of transcription from RNA polymerase II promoter|platelet-derived growth factor receptor signaling pathway|skeletal system morphogenesis|palate development|face morphogenesis|",RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.6,2,10,0.5,1.16,-0.5,1.17,-1.17,0.613,0,0,-1.6,1.4
ENSMUSG00000023990,TFEB,transcription factor EB,nucleus|transcription factor complex|cytoplasm|,"embryonic placenta development|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|autophagy|humoral immune response|lysosome organization|positive regulation of autophagy|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|,10,-0.2,0.344,10,-0.2,0.912,-0.2,1.16,-1.16,0.614,0,0,-1.6,0.9
ENSMUSG00000041852,TCF20,transcription factor 20,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|transcription regulatory region DNA binding|poly(A) RNA binding|metal ion binding|,10,0.4,1.21,10,0.2,0.207,0.3,1.16,1.16,0.614,0,0,-0.8,1.8
ENSMUSG00000032400,ZWILCH,zwilch kinetochore protein,"chromosome, centromeric region|kinetochore|chromosome|",cell cycle|mitotic nuclear division|mitotic cell cycle checkpoint|cell division|,molecular_function|,9,1.6,1.71,9,0.4,2.27,0.2,1.16,1.16,0.614,0,0,-0.1,3
ENSMUSG00000039983,CCDC32,coiled-coil domain containing 32,cellular_component|,biological_process|,molecular_function|,10,0.3,2.52,10,-0.1,0.145,0.4,1.16,1.16,0.614,0,0,-0.5,1.9
ENSMUSG00000071054,SAFB,scaffold attachment factor B,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|intracellular estrogen receptor signaling pathway|growth|hormone metabolic process|positive regulation of transcription from RNA polymerase II promoter|regulation of mRNA processing|",nucleotide binding|core promoter binding|nucleic acid binding|DNA binding|chromatin binding|RNA binding|protein binding|protein kinase binding|sequence-specific DNA binding|poly(A) RNA binding|,10,1,2.83,10,0.1,0.41,0.8,1.15,1.15,0.616,0,0,-0.3,2
ENSMUSG00000093809,BCL2A1A,B cell leukemia/lymphoma 2 related protein A1a,cytoplasm|mitochondrial outer membrane|,B cell homeostasis|negative regulation of B cell apoptotic process|apoptotic process|intrinsic apoptotic signaling pathway in response to DNA damage|regulation of apoptotic process|negative regulation of apoptotic process|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of intrinsic apoptotic signaling pathway|,protein binding|protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|BH domain binding|,9,0.3,2.13,9,0,0,0.2,1.15,1.15,0.616,0,0,-1.1,1.5
ENSMUSG00000030505,PRMT3,protein arginine N-methyltransferase 3,cytoplasm|cytosol|ribosome|,"regulation of transcription, DNA-templated|protein methylation|peptidyl-arginine methylation|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|negative regulation of protein ubiquitination|methylation|histone arginine methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|modified amino acid binding|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.2,1.39,10,-0.2,0.997,0.2,1.15,1.15,0.616,0,0,-1.1,1.5
ENSMUSG00000056910,VMN2R107,"vomeronasal 2, receptor 107",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0.5,3.53,10,-0.1,0.476,0.5,1.15,1.15,0.616,0,0,-0.5,1.9
ENSMUSG00000032253,PHIP,pleckstrin homology domain interacting protein,intracellular|cell|nucleus|extracellular vesicular exosome|,"regulation of protein phosphorylation|protein import into nucleus|cytoskeleton organization|positive regulation of cell proliferation|positive regulation of cell proliferation|insulin receptor signaling pathway|positive regulation of peptidyl-threonine phosphorylation|regulation of cell morphogenesis|positive regulation of peptidyl-serine phosphorylation|regulation of growth|negative regulation of apoptotic process|positive regulation of insulin-like growth factor receptor signaling pathway|positive regulation of mitosis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of extrinsic apoptotic signaling pathway|",insulin receptor binding|protein binding|lysine-acetylated histone binding|,10,0.2,0.518,10,0.2,0.717,0.2,1.14,1.14,0.617,0,0,-0.9,1.7
ENSMUSG00000029591,UNG,uracil DNA glycosylase,nucleus|mitochondrion|mitochondrion|,DNA repair|base-excision repair|cellular response to DNA damage stimulus|metabolic process|somatic hypermutation of immunoglobulin genes|somatic recombination of immunoglobulin gene segments|somatic recombination of immunoglobulin gene segments|negative regulation of apoptotic process|,"uracil DNA N-glycosylase activity|uracil DNA N-glycosylase activity|uracil DNA N-glycosylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hydrolase activity, hydrolyzing N-glycosyl compounds|uridine nucleosidase activity|",10,-0.1,0.629,10,-0.4,1.07,-0.2,1.14,-1.14,0.617,0,0,-1.7,0.8
ENSMUSG00000028411,APTX,aprataxin,chromatin|nuclear chromatin|nucleus|nucleoplasm|nucleoplasm|nucleolus|,"single strand break repair|single strand break repair|DNA catabolic process, exonucleolytic|DNA catabolic process, exonucleolytic|DNA ligation|DNA repair|double-strand break repair|cellular response to DNA damage stimulus|dephosphorylation|regulation of protein stability|response to hydrogen peroxide|polynucleotide 3' dephosphorylation|",DNA binding|chromatin binding|damaged DNA binding|double-stranded DNA binding|double-stranded RNA binding|catalytic activity|GPI-anchor transamidase activity|phosphoglycolate phosphatase activity|hydrolase activity|DNA 5'-adenosine monophosphate hydrolase activity|DNA 5'-adenosine monophosphate hydrolase activity|polynucleotide 3'-phosphatase activity|metal ion binding|protein N-terminus binding|phosphoprotein binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,0.3,1.73,0.2,1.14,1.14,0.617,0,0,-0.8,1.7
ENSMUSG00000026048,ERCC5,"excision repair cross-complementing rodent repair deficiency, complementation group 5","nucleus|DNA replication factor A complex|holo TFIIH complex|DNA-directed RNA polymerase II, holoenzyme|intermediate filament cytoskeleton|","DNA catabolic process, endonucleolytic|DNA repair|transcription-coupled nucleotide-excision repair|nucleotide-excision repair|nucleotide-excision repair, DNA incision, 3'-to lesion|cellular response to DNA damage stimulus|determination of adult lifespan|response to UV|response to UV|UV protection|UV protection|UV protection|response to UV-C|multicellular organism growth|negative regulation of apoptotic process|","bubble DNA binding|DNA binding|double-stranded DNA binding|single-stranded DNA binding|catalytic activity|nuclease activity|endonuclease activity|endodeoxyribonuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|protein homodimerization activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|protein N-terminus binding|",10,0.1,0.047,10,0.5,1.66,0.2,1.13,1.13,0.619,0,0,-0.6,1.8
ENSMUSG00000054766,SET,SET nuclear oncogene,nucleus|nucleus|cytoplasm|endoplasmic reticulum|protein complex|perinuclear region of cytoplasm|,"nucleosome assembly|negative regulation of neuron apoptotic process|negative regulation of transcription, DNA-templated|",DNA binding|,10,0.2,0.462,10,0.5,1.5,0.4,1.13,1.13,0.619,0,0,-0.6,1.8
ENSMUSG00000000134,TFE3,transcription factor E3,nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|,"immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|humoral immune response|regulation of osteoclast differentiation|positive regulation of cell adhesion|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|,10,-0.4,1.08,10,-0.1,0.158,-0.4,1.12,-1.12,0.62,0,0,-1.8,0.6
ENSMUSG00000001761,SMO,smoothened homolog (Drosophila),cytoplasm|cytoplasm|cytoplasm|Golgi apparatus|plasma membrane|plasma membrane|plasma membrane|caveola|cilium|postsynaptic density|membrane|integral component of membrane|dendrite|cell projection|neuronal cell body|neuronal cell body|intracellular membrane-bounded organelle|dendritic growth cone|axonal growth cone|ciliary membrane|extracellular vesicular exosome|primary cilium|,negative regulation of transcription from RNA polymerase II promoter|ossification|vasculogenesis|osteoblast differentiation|in utero embryonic development|cell fate specification|neural crest cell migration|heart looping|positive regulation of neuroblast proliferation|positive regulation of mesenchymal cell proliferation|heart morphogenesis|determination of left/right asymmetry in lateral mesoderm|type B pancreatic cell development|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|smoothened signaling pathway|smoothened signaling pathway|smoothened signaling pathway|positive regulation of hh target transcription factor activity|multicellular organismal development|spermatogenesis|determination of left/right symmetry|ventral midline determination|pattern specification process|central nervous system development|midgut development|positive regulation of cell proliferation|gonad development|anterior/posterior pattern specification|dorsal/ventral pattern formation|cardioblast differentiation|regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|floor plate formation|facial nerve development|cerebellar cortex morphogenesis|thalamus development|dorsal/ventral neural tube patterning|smoothened signaling pathway involved in ventral spinal cord patterning|smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation|central nervous system neuron differentiation|adenohypophysis development|negative regulation of epithelial cell differentiation|exocrine pancreas development|hair follicle morphogenesis|embryonic camera-type eye development|neuron projection regeneration|otolith morphogenesis|protein localization to nucleus|multicellular organism growth|multicellular organism growth|positive regulation of protein import into nucleus|odontogenesis of dentin-containing tooth|muscle cell fate commitment|negative regulation of apoptotic process|negative regulation of DNA binding|negative regulation of DNA binding|positive regulation of smoothened signaling pathway|positive regulation of transcription from RNA polymerase II promoter|cell development|embryonic digestive tract morphogenesis|digestive tract development|embryonic organ development|developmental growth|neuron fate commitment|embryonic neurocranium morphogenesis|embryonic viscerocranium morphogenesis|skeletal muscle fiber development|semicircular canal morphogenesis|axon extension involved in axon guidance|axon extension involved in axon guidance|forebrain morphogenesis|positive regulation of epithelial cell proliferation|protein stabilization|myoblast migration|negative regulation of hair follicle development|canonical Wnt signaling pathway|detection of cell density by contact stimulus involved in contact inhibition|atrial septum morphogenesis|mammary gland epithelial cell differentiation|epithelial-mesenchymal cell signaling|ciliary receptor clustering involved in smoothened signaling pathway|somite development|pancreas morphogenesis|mesenchymal to epithelial transition involved in metanephric renal vesicle formation|positive regulation of branching involved in ureteric bud morphogenesis|regulation of stem cell maintenance|regulation of heart morphogenesis|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|patched binding|drug binding|drug binding|Wnt-protein binding|PDZ domain binding|Wnt-activated receptor activity|,10,-0.4,1.7,10,-0.1,0.412,-0.2,1.11,-1.11,0.622,0,0,-1.8,0.6
ENSMUSG00000054509,PARP4,"poly (ADP-ribose) polymerase family, member 4",nucleus|cytoplasm|spindle|spindle microtubule|membrane|extracellular vesicular exosome|,cellular protein modification process|inflammatory response|cell death|,NAD+ ADP-ribosyltransferase activity|enzyme binding|,10,0.2,1.01,10,0.1,0.265,0.2,1.11,1.11,0.622,0,0,-1.1,1.5
ENSMUSG00000032192,GNB5,"guanine nucleotide binding protein (G protein), beta 5",nucleus|cytosol|plasma membrane|protein complex|cell body|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of voltage-gated calcium channel activity|,signal transducer activity|protein binding|G-protein gamma-subunit binding|GTPase activating protein binding|chaperone binding|,10,0.6,1.93,10,0.3,0.134,0.5,1.11,1.11,0.622,0,0,-0.3,2
ENSMUSG00000037847,NMRK1,nicotinamide riboside kinase 1,cellular_component|,biological_process|phosphorylation|pyridine nucleotide biosynthetic process|,nucleotide binding|molecular_function|ATP binding|kinase activity|transferase activity|metal ion binding|ribosylnicotinamide kinase activity|,10,0.8,0.718,10,-0.2,1.8,-0.2,1.1,-1.1,0.623,0,0,-1.5,1.7
ENSMUSG00000031723,TXNL4B,thioredoxin-like 4B,nucleus|spliceosomal complex|,"mRNA splicing, via spliceosome|mRNA processing|cell cycle|mitotic nuclear division|positive regulation of cell proliferation|RNA splicing|",molecular_function|,10,0.6,3.08,10,0,0,0.5,1.09,1.09,0.625,0,0,-1.1,1.8
ENSMUSG00000005580,ADCY9,adenylate cyclase 9,plasma membrane|membrane|integral component of membrane|axon|dendrite|,cAMP biosynthetic process|cAMP biosynthetic process|cAMP biosynthetic process|activation of adenylate cyclase activity|cyclic nucleotide biosynthetic process|intracellular signal transduction|,nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|ATP binding|lyase activity|phosphorus-oxygen lyase activity|metal ion binding|,10,-0.6,1.28,10,0.1,0.134,0.2,1.09,1.09,0.625,0,0,-1.7,1
ENSMUSG00000065954,TACC1,"transforming, acidic coiled-coil containing protein 1",nucleus|cytoplasm|cytoskeleton|microtubule cytoskeleton|intermediate filament cytoskeleton|,microtubule cytoskeleton organization|cell cycle|cell proliferation|cerebral cortex development|neurogenesis|interkinetic nuclear migration|regulation of microtubule-based process|cell division|,protein domain specific binding|,10,0.3,2.73,10,-0.5,2.33,0.2,1.09,1.09,0.625,0,0,-1.6,1.1
ENSMUSG00000019961,TMPO,thymopoietin,chromatin|nucleus|nuclear envelope|nuclear inner membrane|chromosome|membrane|membrane|integral component of membrane|nuclear membrane|,"regulation of transcription, DNA-templated|",DNA binding|protein binding|,10,0,0,10,-0.2,1.5,-0.2,1.08,-1.08,0.627,0,0,-1.7,0.9
ENSMUSG00000054106,TRY4,trypsin 4,extracellular space|extracellular vesicular exosome|,proteolysis|,serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.0242,10,0.5,1.93,0.2,1.08,1.08,0.627,0,0,-0.8,1.6
ENSMUSG00000031397,TKTL1,transketolase-like 1,cellular_component|nucleus|cytoplasm|,metabolic process|,catalytic activity|transketolase activity|transferase activity|metal ion binding|,10,-1,2.01,10,-0.4,1.6,-0.9,1.08,-1.08,0.627,0,0,-2,1.1
ENSMUSG00000078566,BNIP3,BCL2/adenovirus E1B interacting protein 3,intracellular|nucleus|nuclear envelope|nuclear envelope|nucleoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial outer membrane|mitochondrial outer membrane|endoplasmic reticulum|membrane|integral component of membrane|dendrite|integral component of mitochondrial outer membrane|mitochondrial membrane|mitochondrial membrane|,response to hypoxia|apoptotic process|cell death|granzyme-mediated apoptotic signaling pathway|negative regulation of mitochondrial fusion|mitochondrial protein catabolic process|positive regulation of apoptotic process|positive regulation of programmed cell death|positive regulation of programmed cell death|positive regulation of protein complex disassembly|mitochondrial fragmentation involved in apoptotic process|negative regulation of membrane potential|regulation of mitochondrial membrane permeability|autophagic cell death|brown fat cell differentiation|neuron apoptotic process|defense response to virus|cellular response to hydrogen peroxide|cellular response to cobalt ion|cellular response to hypoxia|reactive oxygen species metabolic process|positive regulation of mitochondrial fission|positive regulation of release of cytochrome c from mitochondria|intrinsic apoptotic signaling pathway|intrinsic apoptotic signaling pathway|mitochondrial outer membrane permeabilization|mitochondrial outer membrane permeabilization|intrinsic apoptotic signaling pathway in response to hypoxia|,identical protein binding|protein homodimerization activity|protein homodimerization activity|protein heterodimerization activity|GTPase binding|,10,0.1,0.0143,10,0.7,3.43,0.6,1.07,1.07,0.628,0,0,-0.3,1.9
ENSMUSG00000050335,LGALS3,"lectin, galactose binding, soluble 3",immunological synapse|immunological synapse|extracellular region|proteinaceous extracellular matrix|extracellular space|nucleus|nucleus|spliceosomal complex|cytoplasm|cytoplasm|mitochondrial inner membrane|external side of plasma membrane|membrane|extracellular matrix|extracellular vesicular exosome|,skeletal system development|immune system process|monocyte chemotaxis|mRNA processing|RNA splicing|cell differentiation|extracellular matrix organization|neutrophil chemotaxis|regulation of T cell proliferation|innate immune response|negative regulation of endocytosis|negative regulation of endocytosis|eosinophil chemotaxis|macrophage chemotaxis|negative regulation of T cell receptor signaling pathway|positive chemotaxis|regulation of T cell apoptotic process|mononuclear cell migration|positive regulation of mononuclear cell migration|positive regulation of calcium ion import|regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of immunological synapse formation|negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of extrinsic apoptotic signaling pathway|,protein binding|IgE binding|carbohydrate binding|chemoattractant activity|laminin binding|poly(A) RNA binding|,10,0.3,2.64,10,-0.4,0.944,0.2,1.07,1.07,0.628,0,0,-1.3,1.4
ENSMUSG00000032591,MST1,macrophage stimulating 1 (hepatocyte growth factor-like),extracellular region|extracellular vesicular exosome|,proteolysis|embryo implantation|,catalytic activity|serine-type endopeptidase activity|,10,-0.1,0.296,10,-0.4,1.72,-0.1,1.06,-1.06,0.63,0,0,-1.8,0.8
ENSMUSG00000028464,TPM2,"tropomyosin 2, beta",cytoplasm|cytoskeleton|muscle thin filament tropomyosin|,muscle contraction|,actin binding|structural constituent of cytoskeleton|protein binding|,10,0,0,10,0.2,1.78,0.2,1.06,1.06,0.63,0,0,-1,1.6
ENSMUSG00000021192,GOLGA5,"golgi autoantigen, golgin subfamily a, 5",Golgi cis cisterna|Golgi trans cisterna|Golgi membrane|Golgi membrane|Golgi apparatus|Golgi medial cisterna|cis-Golgi network|membrane|membrane|integral component of membrane|COPI-coated vesicle membrane|Golgi cisterna|,"retrograde transport, vesicle recycling within Golgi|Golgi organization|Golgi vesicle transport|","protein binding|Rab GTPase binding|protein binding, bridging|protein homodimerization activity|",10,-0.1,0.515,10,-0.2,0.904,-0.2,1.05,-1.05,0.632,0,0,-1.7,0.9
ENSMUSG00000026875,TRAF1,TNF receptor-associated factor 1,cytoplasm|,apoptotic process|signal transduction|regulation of apoptotic process|positive regulation of NF-kappaB transcription factor activity|regulation of extrinsic apoptotic signaling pathway|,tumor necrosis factor receptor binding|protein binding|zinc ion binding|ubiquitin protein ligase binding|thioesterase binding|,10,0,0,10,0.3,1.63,0.2,1.04,1.04,0.633,0,0,-1,1.6
ENSMUSG00000020458,RTN4,reticulon 4,intracellular|nuclear envelope|nuclear envelope|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|integral component of endoplasmic reticulum membrane|cell projection|neuron projection|neuronal cell body|neuronal cell body|myelin sheath|protein complex|extracellular vesicular exosome|,angiogenesis|nervous system development|axonal fasciculation|axonal fasciculation|negative regulation of neuron projection development|cerebral cortex radial glia guided migration|negative regulation of cell growth|regulation of cell migration|negative regulation of axon extension|negative regulation of axon extension|negative regulation of axon extension|positive regulation of dopamine secretion|negative regulation of neuron differentiation|positive regulation of glial cell differentiation|regulation of axon regeneration|negative regulation of axonogenesis|regulation of sensory perception of pain|regulation of nervous system development|cardiac epithelial to mesenchymal transition|negative regulation of neuron projection regeneration|endoplasmic reticulum tubular network organization|regulation of branching morphogenesis of a nerve|regulation of branching morphogenesis of a nerve|,protein binding|protein complex binding|poly(A) RNA binding|,10,0,0,10,0.2,1.75,0.2,1.04,1.04,0.633,0,0,-0.9,1.6
ENSMUSG00000033751,GADD45GIP1,"growth arrest and DNA-damage-inducible, gamma interacting protein 1",nucleus|mitochondrion|,cell cycle|,None,10,0,0,10,0.4,2.75,0.4,1.03,1.03,0.635,0,0,-0.5,1.9
ENSMUSG00000003873,BAX,BCL2-associated X protein,intracellular|intracellular|cell|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane|mitochondrial permeability transition pore complex|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|cytosol|cytosol|membrane|membrane|integral component of membrane|mitochondrial membrane|mitochondrial membrane|pore complex|extracellular vesicular exosome|Bcl-2 family protein complex|BAX complex|BAX complex|,ovarian follicle development|ovarian follicle development|neuron migration|leukocyte homeostasis|T cell homeostatic proliferation|B cell homeostasis|B cell homeostasis|B cell apoptotic process|B cell apoptotic process|kidney development|release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|blood vessel remodeling|myeloid cell homeostasis|B cell negative selection|B cell homeostatic proliferation|positive regulation of B cell apoptotic process|glycosphingolipid metabolic process|regulation of nitrogen utilization|apoptotic process|apoptotic process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|transformed cell apoptotic process|cellular response to DNA damage stimulus|inner mitochondrial membrane organization|outer mitochondrial membrane organization|germ cell development|spermatogenesis|spermatogenesis|nervous system development|sex differentiation|mitochondrial fusion|mitochondrial fusion|cell proliferation|cell proliferation|negative regulation of cell proliferation|male gonad development|male gonad development|extrinsic apoptotic signaling pathway via death domain receptors|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|apoptotic mitochondrial changes|apoptotic mitochondrial changes|fertilization|response to wounding|response to toxic substance|response to toxic substance|response to salt stress|post-embryonic development|response to ionizing radiation|response to ionizing radiation|establishment or maintenance of transmembrane electrochemical gradient|response to gamma radiation|positive regulation of calcium ion transport into cytosol|hypothalamus development|cerebral cortex development|negative regulation of protein binding|positive regulation of protein oligomerization|negative regulation of endoplasmic reticulum calcium ion concentration|release of matrix enzymes from mitochondria|negative regulation of peptidyl-serine phosphorylation|regulation of mammary gland epithelial cell proliferation|cellular response to UV|limb morphogenesis|ectopic germ cell programmed cell death|ectopic germ cell programmed cell death|odontogenesis of dentin-containing tooth|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of protein homodimerization activity|regulation of protein heterodimerization activity|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|mitochondrial fragmentation involved in apoptotic process|development of secondary sexual characteristics|cellular respiration|retinal cell programmed cell death|positive regulation of developmental pigmentation|negative regulation of fibroblast proliferation|spermatid differentiation|post-embryonic camera-type eye morphogenesis|response to axon injury|homeostasis of number of cells|homeostasis of number of cells|homeostasis of number of cells within a tissue|protein oligomerization|protein homooligomerization|protein homooligomerization|positive regulation of release of sequestered calcium ion into cytosol|neuron apoptotic process|neuron apoptotic process|regulation of cell cycle|transmembrane transport|Sertoli cell proliferation|retina development in camera-type eye|positive regulation of apoptotic process involved in mammary gland involution|vagina development|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|thymocyte apoptotic process|mitochondrion morphogenesis|cellular response to organic substance|intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of release of cytochrome c from mitochondria|apoptotic signaling pathway|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|intrinsic apoptotic signaling pathway|activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|positive regulation of endoplasmic reticulum unfolded protein response|regulation of mitochondrial membrane permeability involved in apoptotic process|positive regulation of mitochondrial membrane permeability involved in apoptotic process|apoptotic process involved in patterning of blood vessels|apoptotic process involved in embryonic digit morphogenesis|regulation of mitochondrial membrane permeability involved in programmed necrotic cell death|positive regulation of apoptotic DNA fragmentation|retinal cell apoptotic process|B cell receptor apoptotic signaling pathway|negative regulation of apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of intrinsic apoptotic signaling pathway|positive regulation of intrinsic apoptotic signaling pathway|,protein binding|lipid binding|channel activity|channel activity|heat shock protein binding|protein complex binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|chaperone binding|BH domain binding|BH3 domain binding|,10,0.1,0.179,10,0.2,1.14,0.2,1.02,1.02,0.637,0,0,-1.2,1.5
ENSMUSG00000031673,CDH11,cadherin 11,cytoplasm|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|corticospinal tract morphogenesis|,calcium ion binding|metal ion binding|,10,0.3,2.58,10,-0.3,1.43,0.2,1.02,1.02,0.637,0,0,-1.1,1.5
ENSMUSG00000031844,HSD17B2,hydroxysteroid (17-beta) dehydrogenase 2,membrane|integral component of membrane|intracellular membrane-bounded organelle|,in utero embryonic development|placenta development|lipid metabolic process|steroid biosynthetic process|androgen biosynthetic process|estrogen biosynthetic process|metabolic process|response to retinoic acid|oxidation-reduction process|,estradiol 17-beta-dehydrogenase activity|oxidoreductase activity|testosterone dehydrogenase (NAD+) activity|,10,0.4,2.81,10,0,0,0.3,1.02,1.02,0.637,0,0,-0.5,1.9
ENSMUSG00000022770,DLG1,"discs, large homolog 1 (Drosophila)",immunological synapse|basal lamina|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|microtubule|plasma membrane|plasma membrane|cell-cell junction|cell-cell adherens junction|tight junction|cytoplasmic side of plasma membrane|basal plasma membrane|postsynaptic density|postsynaptic density|membrane|basolateral plasma membrane|basolateral plasma membrane|basolateral plasma membrane|lateral plasma membrane|cell junction|cell junction|T-tubule|cell projection membrane|neuromuscular junction|node of Ranvier|myelin sheath abaxonal region|presynaptic membrane|neuron projection|lateral loop|membrane raft|synapse|postsynaptic membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|MPP7-DLG1-LIN7 complex|,ureteric bud development|branching involved in ureteric bud morphogenesis|immunological synapse formation|endothelial cell proliferation|lens development in camera-type eye|T cell cytokine production|actin filament organization|protein localization|protein localization|positive regulation of cell proliferation|single organismal cell-cell adhesion|peristalsis|positive regulation of actin filament polymerization|cortical actin cytoskeleton organization|membrane raft organization|regulation of myelination|activation of protein kinase activity|regulation of protein localization|positive regulation of multicellular organism growth|T cell activation|negative regulation of T cell proliferation|regulation of membrane potential|regulation of membrane potential|amyloid precursor protein metabolic process|positive regulation of potassium ion transport|negative regulation of mitotic cell cycle|reproductive structure development|positive regulation of developmental growth|embryonic skeletal system morphogenesis|tissue morphogenesis|smooth muscle tissue development|negative regulation of epithelial cell proliferation|negative regulation of protein kinase B signaling|hard palate development|tight junction assembly|protein localization to plasma membrane|positive regulation of establishment of protein localization to plasma membrane|,protein binding|protein C-terminus binding|potassium channel regulator activity|protein kinase binding|phosphatase binding|PDZ domain binding|mitogen-activated protein kinase kinase binding|protein complex scaffold|ionotropic glutamate receptor binding|ion channel binding|L27 domain binding|,9,0,0,9,-0.2,1.67,-0.2,1.01,-1.01,0.638,0,0,-1.7,1
ENSMUSG00000040151,HS2ST1,heparan sulfate 2-O-sulfotransferase 1,Golgi apparatus|membrane|membrane|integral component of membrane|,"heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process|heparin metabolic process|ureteric bud formation|","N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,-0.4,2.36,10,0,0,-0.2,1.01,-1.01,0.638,0,0,-1.5,1.4
ENSMUSG00000023088,ABCC1,"ATP-binding cassette, sub-family C (CFTR/MRP), member 1",cytoplasm|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|extracellular vesicular exosome|,ATP catabolic process|transport|drug transmembrane transport|response to oxidative stress|plasma membrane long-chain fatty acid transport|positive regulation of cell migration|phospholipid efflux|glutathione transmembrane transport|response to drug|xenobiotic transport|daunorubicin transport|drug export|transmembrane transport|cell chemotaxis|negative regulation of neuron death|,"nucleotide binding|transporter activity|long-chain fatty acid transporter activity|ATP binding|xenobiotic-transporting ATPase activity|drug transmembrane transporter activity|glutathione S-conjugate-exporting ATPase activity|efflux transmembrane transporter activity|hydrolase activity|ATPase activity|lipid-transporting ATPase activity|glutathione transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of substances|sphingolipid transporter activity|",10,0.1,0.294,10,0.3,1.04,0.2,1.01,1.01,0.638,0,0,-0.9,1.7
ENSMUSG00000023092,FHL1,four and a half LIM domains 1,nucleus|cytoplasm|plasma membrane|,regulation of membrane depolarization|multicellular organismal development|negative regulation of G2/M transition of mitotic cell cycle|cell differentiation|negative regulation of cell growth|positive regulation of potassium ion transport|regulation of potassium ion transmembrane transporter activity|negative regulation of G1/S transition of mitotic cell cycle|,zinc ion binding|ion channel binding|metal ion binding|,10,0.3,1.13,10,0.2,0.287,0.2,1.01,1.01,0.638,0,0,-0.8,1.8
ENSMUSG00000037362,NOV,nephroblastoma overexpressed gene,extracellular region|axon|dendrite|extracellular matrix|neuronal cell body|intracellular membrane-bounded organelle|,regulation of cell growth|regulation of gene expression|,insulin-like growth factor binding|growth factor activity|,10,0.3,1.64,10,-0.2,0.0184,0.2,1.01,1.01,0.638,0,0,-1,1.7
ENSMUSG00000031162,GATA1,GATA binding protein 1,nucleus|nucleus|transcription factor complex|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell-cell signaling|negative regulation of cell proliferation|male gonad development|regulation of glycoprotein biosynthetic process|regulation of glycoprotein biosynthetic process|regulation of definitive erythrocyte differentiation|regulation of definitive erythrocyte differentiation|myeloid cell differentiation|erythrocyte differentiation|erythrocyte differentiation|erythrocyte differentiation|megakaryocyte differentiation|megakaryocyte differentiation|megakaryocyte differentiation|megakaryocyte differentiation|platelet formation|platelet formation|negative regulation of bone mineralization|positive regulation of osteoblast proliferation|embryonic hemopoiesis|eosinophil fate commitment|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of erythrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell development|erythrocyte development|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|platelet aggregation|platelet aggregation|transcriptional activation by promoter-enhancer looping|dendritic cell differentiation|cellular response to thyroid hormone stimulus|negative regulation of transcription regulatory region DNA binding|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|","transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II transcription factor binding|enhancer sequence-specific DNA binding|p53 binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|DNA binding, bending|chromatin DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|C2H2 zinc finger domain binding|",10,0,0,10,-0.2,1.52,-0.2,1,-1,0.64,0,0,-1.6,1
ENSMUSG00000076430,HUS1B,Hus1 homolog b (S. pombe),cellular_component|nucleolus|checkpoint clamp complex|,DNA damage checkpoint|DNA repair|biological_process|,molecular_function|,9,0.1,0.0617,10,0.2,1.3,0.2,0.998,0.998,0.64,0,0,-1,1.7
ENSMUSG00000026436,ELK4,"ELK4, member of ETS oncogene family",nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|histone H3 deacetylation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.9,1.66,10,0,0,0.8,0.994,0.994,0.641,0,0,-0.4,2
ENSMUSG00000006281,TEP1,telomerase associated protein 1,"chromosome, telomeric region|nucleus|chromosome|telomerase holoenzyme complex|cytoplasm|nuclear matrix|ribonucleoprotein complex|",telomere maintenance via recombination|RNA-dependent DNA replication|,nucleotide binding|telomerase activity|RNA binding|ATP binding|,9,0.4,0.813,10,0.8,0.349,0.4,0.986,0.986,0.642,0,0,-0.6,1.9
ENSMUSG00000001656,HOXC11,homeobox C11,nucleus|cytoplasm|,"skeletal system development|metanephros development|organ induction|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|anterior/posterior pattern specification|proximal/distal pattern formation|embryonic digit morphogenesis|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal joint morphogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|,10,0.1,0.336,10,0.2,0.729,0.1,0.977,0.977,0.644,0,0,-0.9,1.7
ENSMUSG00000022772,SENP5,SUMO/sentrin specific peptidase 5,nucleus|nucleolus|intracellular membrane-bounded organelle|,proteolysis|cell cycle|biological_process|cell division|,molecular_function|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0,0,10,0.2,1.94,0.2,0.973,0.973,0.645,0,0,-1.2,1.5
ENSMUSG00000028465,TLN1,talin 1,ruffle|cytoplasm|microtubule organizing center|cytoskeleton|plasma membrane|focal adhesion|focal adhesion|actin cytoskeleton|membrane|cell junction|cell projection|extracellular vesicular exosome|,cytoskeletal anchoring at plasma membrane|cell-substrate junction assembly|cell adhesion|cortical actin cytoskeleton organization|,actin binding|insulin receptor binding|integrin binding|structural molecule activity|structural constituent of cytoskeleton|protein binding|vinculin binding|LIM domain binding|protein complex binding|,10,0,0,10,0.2,1.9,0.2,0.972,0.972,0.645,0,0,-1.4,1.4
ENSMUSG00000029651,MTUS2,microtubule associated tumor suppressor candidate 2,cytoplasm|centrosome|cytoskeleton|microtubule|cytoplasmic microtubule|,None,microtubule binding|protein homodimerization activity|,10,-0.2,0.972,10,-0.1,0.296,-0.1,0.964,-0.964,0.646,0,0,-1.4,1.3
ENSMUSG00000004668,ABCA13,"ATP-binding cassette, sub-family A (ABC1), member 13",cellular_component|membrane|integral component of membrane|,transport|biological_process|,nucleotide binding|ATP binding|ATPase activity|,10,-0.5,2.28,10,0,0,-0.2,0.956,-0.956,0.647,0,0,-1.8,0.7
ENSMUSG00000028310,PPP3R2,"protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II)",None,glycogen metabolic process|defense response|sperm displacement|dephosphorylation|,calcium-dependent protein serine/threonine phosphatase activity|calcium ion binding|metal ion binding|,10,0.2,0.0805,10,0.2,0.94,0.2,0.944,0.944,0.649,0,0,-0.8,1.7
ENSMUSG00000015647,LAMA5,"laminin, alpha 5",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basal lamina|laminin-1 complex|laminin-5 complex|extracellular space|nucleus|extracellular matrix|laminin-10 complex|laminin-10 complex|extracellular vesicular exosome|,branching involved in ureteric bud morphogenesis|morphogenesis of a polarized epithelium|neural crest cell migration|hair follicle development|cell adhesion|integrin-mediated signaling pathway|muscle organ development|organ morphogenesis|morphogenesis of embryonic epithelium|cell migration|regulation of cell adhesion|lung development|regulation of cell migration|substrate adhesion-dependent cell spreading|regulation of cell proliferation|cilium assembly|odontogenesis of dentin-containing tooth|regulation of embryonic development|branching morphogenesis of an epithelial tube|branching involved in salivary gland morphogenesis|establishment of protein localization to plasma membrane|,receptor binding|integrin binding|integrin binding|protein binding|,10,-0.2,0.63,10,-0.3,0.458,-0.2,0.942,-0.942,0.65,0,0,-1.6,1.1
ENSMUSG00000033308,DPYD,dihydropyrimidine dehydrogenase,cytoplasm|cytosol|cytosol|,purine nucleobase catabolic process|pyrimidine nucleobase catabolic process|pyrimidine nucleobase catabolic process|thymine catabolic process|uracil catabolic process|thymidine catabolic process|UMP biosynthetic process|response to nutrient|circadian rhythm|uracil metabolic process|response to drug|oxidation-reduction process|,"nucleotide binding|uracil binding|catalytic activity|dihydroorotate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|dihydropyrimidine dehydrogenase (NADP+) activity|dihydropyrimidine dehydrogenase (NADP+) activity|protein homodimerization activity|metal ion binding|NADP binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0,0,10,-0.2,1.63,-0.2,0.931,-0.931,0.652,0,0,-1.7,0.9
ENSMUSG00000031628,CASP3,caspase 3,nucleus|cytoplasm|cytoplasm|cytosol|death-inducing signaling complex|membrane raft|,B cell homeostasis|release of cytochrome c from mitochondria|proteolysis|proteolysis|proteolysis|apoptotic process|apoptotic process|cellular response to DNA damage stimulus|heart development|sensory perception of sound|learning or memory|extrinsic apoptotic signaling pathway via death domain receptors|intrinsic apoptotic signaling pathway in response to oxidative stress|response to UV|response to UV|response to wounding|response to glucose|protein processing|neuron differentiation|keratinocyte differentiation|erythrocyte differentiation|erythrocyte differentiation|negative regulation of B cell proliferation|glial cell apoptotic process|intracellular signal transduction|response to hydrogen peroxide|T cell homeostasis|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of catalytic activity|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|cell fate commitment|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of cell cycle|negative regulation of activated T cell proliferation|neuron apoptotic process|neuron apoptotic process|neuron apoptotic process|cellular response to organic substance|extrinsic apoptotic signaling pathway in absence of ligand|execution phase of apoptosis|execution phase of apoptosis|execution phase of apoptosis|execution phase of apoptosis|regulation of apoptotic DNA fragmentation|,protease binding|aspartic-type endopeptidase activity|aspartic-type endopeptidase activity|cysteine-type endopeptidase activity|cysteine-type endopeptidase activity|cyclin-dependent protein serine/threonine kinase inhibitor activity|death receptor binding|protein binding|peptidase activity|peptidase activity|peptidase activity|peptidase activity|cysteine-type peptidase activity|cysteine-type peptidase activity|phospholipase A2 activator activity|hydrolase activity|protein complex binding|cysteine-type endopeptidase activity involved in apoptotic process|cysteine-type endopeptidase activity involved in apoptotic process|cysteine-type endopeptidase activity involved in execution phase of apoptosis|cysteine-type endopeptidase activity involved in execution phase of apoptosis|,10,-0.1,0.307,10,-0.3,1.22,-0.2,0.913,-0.913,0.655,0,0,-1.7,0.9
ENSMUSG00000000346,DAZAP2,DAZ associated protein 2,nucleus|transcription factor complex|cytoplasm|,None,protein binding|WW domain binding|,10,0,0,10,0.2,1.35,0.1,0.91,0.91,0.656,0,0,-1.3,1.5
ENSMUSG00000000184,CCND2,cyclin D2,cyclin-dependent protein kinase holoenzyme complex|chromatin|nucleus|nucleus|cytoplasm|cytosol|membrane|nuclear membrane|,regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|positive regulation of protein phosphorylation|cell cycle|positive regulation of cell proliferation|positive regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of epithelial cell proliferation|cell division|regulation of cell cycle|,protein binding|protein kinase binding|,10,0,0,10,0.9,1.48,0.1,0.909,0.909,0.656,0,0,-0.4,2
ENSMUSG00000039960,RHOU,"ras homolog gene family, member U",intracellular|Golgi apparatus|plasma membrane|membrane|cell junction|cell projection|,G1/S transition of mitotic cell cycle|GTP catabolic process|cytoskeleton organization|small GTPase mediated signal transduction|regulation of cell shape|regulation of cell shape|Rac protein signal transduction|actin cytoskeleton organization|,nucleotide binding|GTPase activity|GTP binding|metal ion binding|,9,0,0,9,-0.3,1.69,-0.3,0.906,-0.906,0.657,0,0,-1.9,0.7
ENSMUSG00000020150,GAMT,guanidinoacetate methyltransferase,cell projection|extracellular vesicular exosome|,creatine biosynthetic process|creatine biosynthetic process|spermatogenesis|organ morphogenesis|methylation|regulation of multicellular organism growth|S-adenosylhomocysteine metabolic process|S-adenosylmethionine metabolic process|,methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|transferase activity|guanidinoacetate N-methyltransferase activity|protein homodimerization activity|,10,0.2,1.03,10,0.1,0.056,0.1,0.897,0.897,0.658,0,0,-1.1,1.6
ENSMUSG00000031158,TIMM17B,translocase of inner mitochondrial membrane 17b,mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane presequence translocase complex|membrane|integral component of membrane|integral component of mitochondrial inner membrane|,transport|intracellular protein transport|protein transport|,P-P-bond-hydrolysis-driven protein transmembrane transporter activity|,10,-0.2,0.693,10,-0.2,0.282,-0.2,0.896,-0.896,0.658,0,0,-1.5,1.1
ENSMUSG00000020364,ZFP354A,zinc finger protein 354A,intracellular|nucleus|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nucleolar fragmentation|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.4,0.211,10,0.2,0.81,0.3,0.879,0.879,0.661,0,0,-0.7,1.9
ENSMUSG00000038607,GNG10,"guanine nucleotide binding protein (G protein), gamma 10",heterotrimeric G-protein complex|plasma membrane|membrane|extracellular vesicular exosome|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|,9,0,0,9,-0.3,2.27,-0.2,0.877,-0.877,0.662,0,0,-1.8,0.9
ENSMUSG00000021572,CEP72,centrosomal protein 72,cytoplasm|centrosome|cytoskeleton|,spindle organization|gamma-tubulin complex localization|,identical protein binding|,10,-1,2.64,10,1,1.24,0.1,0.876,0.876,0.662,0,0,-2,1.4
ENSMUSG00000024899,PAPSS2,3'-phosphoadenosine 5'-phosphosulfate synthase 2,None,sulfate assimilation|blood coagulation|metabolic process|phosphorylation|bone development|,nucleotide binding|catalytic activity|adenylylsulfate kinase activity|sulfate adenylyltransferase (ATP) activity|ATP binding|kinase activity|transferase activity|nucleotidyltransferase activity|,10,-0.9,3.25,10,0.1,0.235,-0.8,0.871,-0.871,0.663,0,0,-2,1
ENSMUSG00000026527,RGS7,regulator of G protein signaling 7,nucleus|cytoplasm|cytosol|heterotrimeric G-protein complex|plasma membrane|plasma membrane|protein complex|dendrite terminus|,G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|negative regulation of signal transduction|intracellular signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,signal transducer activity|GTPase activator activity|GTPase activator activity|protein binding|G-protein beta-subunit binding|,10,0,0,10,1,2.34,1,0.869,0.869,0.663,0,0,-0.2,2
ENSMUSG00000009633,G0S2,G0/G1 switch gene 2,mitochondrion|,apoptotic process|extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|,None,10,0,0,10,0.6,3.7,0.6,0.869,0.869,0.663,0,0,-0.4,1.9
ENSMUSG00000064302,CLASP1,CLIP associating protein 1,"chromosome, centromeric region|kinetochore|chromosome|cytoplasm|Golgi apparatus|centrosome|kinetochore microtubule|cytoskeleton|microtubule|spindle microtubule|cytoplasmic microtubule|cytoplasmic microtubule|cell cortex|membrane|cortical microtubule cytoskeleton|centrosomal corona|extracellular vesicular exosome|",microtubule cytoskeleton organization|microtubule bundle formation|microtubule nucleation|negative regulation of microtubule depolymerization|negative regulation of microtubule depolymerization|cell cycle|mitotic nuclear division|exit from mitosis|microtubule organizing center organization|negative regulation of microtubule polymerization or depolymerization|microtubule anchoring|establishment of spindle orientation|cell division|,protein binding|microtubule binding|microtubule binding|kinetochore binding|microtubule plus-end binding|,10,-0.2,0.481,10,-0.3,0.58,-0.2,0.868,-0.868,0.663,0,0,-1.8,0.6
ENSMUSG00000022389,TEF,thyrotroph embryonic factor,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|sequence-specific DNA binding|protein heterodimerization activity|,10,-0.6,3.55,10,0,0,-0.5,0.864,-0.864,0.664,0,0,-1.9,0.5
ENSMUSG00000036816,ATOH7,atonal homolog 7 (Drosophila),nucleus|,"neural retina development|neural retina development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|circadian rhythm|entrainment of circadian clock|optic nerve development|cell differentiation|",DNA binding|protein dimerization activity|,10,0.2,0.334,10,0.2,0.603,0.2,0.86,0.86,0.665,0,0,-1.6,1.2
ENSMUSG00000071347,C1QTNF9,C1q and tumor necrosis factor related protein 9,extracellular region|collagen trimer|extracellular vesicular exosome|,None,hormone activity|,10,0.7,3.08,10,0,0,0.1,0.848,0.848,0.667,0,0,-0.4,2
ENSMUSG00000056267,CEP70,centrosomal protein 70,nucleus|cytoplasm|centrosome|cytoskeleton|nuclear membrane|,biological_process|,molecular_function|,9,-0.2,0.654,9,-0.1,0.297,-0.2,0.842,-0.842,0.668,0,0,-1.8,1
ENSMUSG00000029714,GIGYF1,GRB10 interacting GYF protein 1,cellular_component|,insulin-like growth factor receptor signaling pathway|,protein binding|,10,0.2,1.45,10,0,0,0.1,0.838,0.838,0.669,0,0,-1.4,1.4
ENSMUSG00000015745,PLEKHO1,"pleckstrin homology domain containing, family O member 1",nucleus|cytoplasm|membrane|,None,None,10,-0.4,0.879,10,0.2,0.351,-0.2,0.829,-0.829,0.671,0,0,-1.7,0.9
ENSMUSG00000038332,SESN1,sestrin 1,nucleus|,regulation of protein kinase B signaling|regulation of response to reactive oxygen species|,molecular_function|,10,-0.7,2.55,10,-0.1,0.104,-0.1,0.823,-0.823,0.672,0,0,-1.9,1.2
ENSMUSG00000026928,CARD9,"caspase recruitment domain family, member 9",cytoplasm|,immune system process|I-kappaB kinase/NF-kappaB signaling|response to fungus|response to peptidoglycan|response to muramyl dipeptide|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of stress-activated MAPK cascade|positive regulation of stress-activated MAPK cascade|response to drug|regulation of tumor necrosis factor biosynthetic process|regulation of apoptotic process|response to exogenous dsRNA|regulation of interleukin-2 biosynthetic process|innate immune response|positive regulation of innate immune response|regulation of interleukin-6 biosynthetic process|positive regulation of JNK cascade|positive regulation of JNK cascade|defense response to Gram-positive bacterium|defense response to virus|,protein binding|protein domain specific binding|protein homodimerization activity|CARD domain binding|,10,0,0,10,0.3,2.39,0.3,0.811,0.811,0.674,0,0,-0.8,1.8
ENSMUSG00000022598,PSCA,prostate stem cell antigen,membrane|extracellular vesicular exosome|,None,None,10,0,0,10,0.2,1.34,0.1,0.811,0.811,0.674,0,0,-1,1.7
ENSMUSG00000004939,NMRK2,nicotinamide riboside kinase 2,intracellular|,phosphorylation|pyridine nucleotide biosynthetic process|negative regulation of myoblast differentiation|,nucleotide binding|protein binding|ATP binding|kinase activity|transferase activity|metal ion binding|ribosylnicotinamide kinase activity|,10,-0.2,1.37,10,0,0,-0.1,0.81,-0.81,0.674,0,0,-1.6,1.1
ENSMUSG00000026609,USH2A,"Usher syndrome 2A (autosomal recessive, mild)",photoreceptor inner segment|stereocilia ankle link|stereocilia ankle link complex|extracellular region|basement membrane|basement membrane|cytoplasm|plasma membrane|membrane|integral component of membrane|apical plasma membrane|photoreceptor connecting cilium|stereocilium|stereocilium bundle|cell projection|neuronal cell body|terminal bouton|synapse|stereocilium membrane|,visual perception|sensory perception of sound|photoreceptor cell maintenance|photoreceptor cell maintenance|maintenance of organ identity|response to stimulus|sensory perception of light stimulus|inner ear receptor cell differentiation|,protein binding|collagen binding|collagen binding|myosin binding|,10,0.4,2.88,10,-0.1,0.167,0.3,0.808,0.808,0.674,0,0,-0.7,1.8
ENSMUSG00000002233,RHOC,"ras homolog gene family, member C",intracellular|nucleus|cytosol|plasma membrane|membrane|cleavage furrow|extracellular vesicular exosome|,cytokinesis|signal transduction|small GTPase mediated signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|apical junction assembly|apical junction assembly|,nucleotide binding|signal transducer activity|protein binding|GTP binding|,10,0.3,0.669,10,0.1,0.45,0.3,0.807,0.807,0.674,0,0,-0.5,1.9
ENSMUSG00000024339,TAP2,"transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)",extracellular region|endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|MHC class I peptide loading complex|TAP complex|intracellular membrane-bounded organelle|host cell|,"positive regulation of T cell mediated cytotoxicity|positive regulation of T cell mediated cytotoxicity|positive regulation of T cell mediated cytotoxicity|response to molecule of bacterial origin|immune system process|antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent|antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent|antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent|antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent|positive regulation of antigen processing and presentation of peptide antigen via MHC class I|positive regulation of antigen processing and presentation of peptide antigen via MHC class I|ATP catabolic process|protein complex assembly|transport|protein transport|peptide transport|intracellular transport of viral protein in host cell|antigen processing and presentation of endogenous peptide antigen via MHC class I|protection from natural killer cell mediated cytotoxicity|cytosol to ER transport|peptide antigen transport|transmembrane transport|transmembrane transport|","nucleotide binding|transporter activity|protein binding|ATP binding|peptide transporter activity|peptide antigen-transporting ATPase activity|ATPase activity|MHC class Ib protein binding|MHC class I protein binding|MHC class I protein binding|peptide antigen binding|ATPase activity, coupled to transmembrane movement of substances|protein homodimerization activity|ADP binding|TAP1 binding|TAP1 binding|TAP2 binding|tapasin binding|protein heterodimerization activity|",10,0,0,10,0.3,2.02,0.2,0.802,0.802,0.675,0,0,-0.7,1.9
ENSMUSG00000059049,FREM1,Fras1 related extracellular matrix protein 1,extracellular region|proteinaceous extracellular matrix|basement membrane|integral component of membrane|,cell communication|cell adhesion|cell-matrix adhesion|multicellular organismal development|craniofacial suture morphogenesis|,carbohydrate binding|metal ion binding|,10,0.1,0.269,10,0.2,0.617,0.1,0.8,0.8,0.676,0,0,-0.9,1.7
ENSMUSG00000037111,SETD7,SET domain containing (lysine methyltransferase) 7,nucleus|chromosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|peptidyl-lysine monomethylation|peptidyl-lysine dimethylation|methylation|histone lysine methylation|",p53 binding|methyltransferase activity|protein-lysine N-methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|,10,-0.5,1.98,10,-0.1,0.34,-0.3,0.798,-0.798,0.676,0,0,-1.7,1
ENSMUSG00000032274,CYP19A1,"cytochrome P450, family 19, subfamily a, polypeptide 1",cytoplasm|endoplasmic reticulum|cytosol|synaptic vesicle|membrane|neuronal cell body|terminal bouton|dendritic spine|axon terminus|synapse|,estrogen biosynthetic process|C21-steroid hormone metabolic process|androgen metabolic process|androgen metabolic process|negative regulation of bone resorption|regulation of synapse structure and activity|oxidation-reduction process|prostate gland growth|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|metal ion binding|aromatase activity|",10,0,0,10,-0.2,1.93,-0.2,0.798,-0.798,0.676,0,0,-1.6,1.1
ENSMUSG00000025225,NFKB2,"nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100",nucleus|nucleus|cytoplasm|cytosol|Bcl3/NF-kappaB2 complex|,"follicular dendritic cell differentiation|germinal center formation|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|extracellular matrix organization|NIK/NF-kappaB signaling|lymph node development|spleen development|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.3,0.4,10,-0.2,0.5,-0.2,0.796,-0.796,0.676,0,0,-1.6,1.1
ENSMUSG00000028163,NFKB1,"nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105",nucleus|nucleus|cytoplasm|mitochondrion|cytosol|cytosol|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|response to oxidative stress|signal transduction|negative regulation of calcidiol 1-monooxygenase activity|negative regulation of apoptotic process|negative regulation of interleukin-12 biosynthetic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|lymph node development|negative regulation of inflammatory response|cellular response to lipopolysaccharide|cellular response to nicotine|cellular response to interleukin-6|cellular response to peptide hormone stimulus|positive regulation of canonical Wnt signaling pathway|positive regulation of hyaluronan biosynthetic process|positive regulation of miRNA metabolic process|",regulatory region DNA binding|transcription regulatory region sequence-specific DNA binding|nucleic acid binding transcription factor activity|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|heat shock protein binding|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.1,0.334,10,0.2,0.667,0.1,0.795,0.795,0.676,0,0,-0.9,1.7
ENSMUSG00000055170,IFNG,interferon gamma,extracellular region|extracellular space|extracellular space|intracellular|cell|external side of plasma membrane|,"protein import into nucleus, translocation|negative regulation of transcription from RNA polymerase II promoter|neutrophil apoptotic process|regulation of the force of heart contraction|positive regulation of mesenchymal cell proliferation|adaptive immune response|CD8-positive, alpha-beta T cell differentiation involved in immune response|negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|regulation of transcription, DNA-templated|apoptotic process|inflammatory cell apoptotic process|immune response|humoral immune response|cell cycle arrest|negative regulation of cell proliferation|response to virus|antigen processing and presentation|neutrophil chemotaxis|neutrophil chemotaxis|endoplasmic reticulum unfolded protein response|negative regulation of myelination|positive regulation of synaptic transmission, cholinergic|negative regulation of interleukin-17 production|positive regulation of interleukin-12 production|positive regulation of interleukin-12 production|positive regulation of interleukin-23 production|positive regulation of tumor necrosis factor production|positive regulation of peptidyl-serine phosphorylation of STAT protein|positive regulation of smooth muscle cell apoptotic process|regulation of growth|positive regulation of T cell proliferation|positive regulation of tyrosine phosphorylation of Stat1 protein|defense response to bacterium|defense response to protozoan|negative regulation of growth of symbiont in host|negative regulation of growth of symbiont involved in interaction with host|positive regulation of chemokine biosynthetic process|positive regulation of chemokine biosynthetic process|positive regulation of interleukin-12 biosynthetic process|positive regulation of MHC class II biosynthetic process|positive regulation of interleukin-6 biosynthetic process|positive regulation of interleukin-6 biosynthetic process|positive regulation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthetic process|positive regulation of neuron differentiation|positive regulation of osteoclast differentiation|positive regulation of cell adhesion|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of isotype switching to IgG isotypes|negative regulation of smooth muscle cell proliferation|positive regulation of interleukin-1 beta secretion|regulation of immune response|regulation of insulin secretion|sensory perception of mechanical stimulus|positive regulation of membrane protein ectodomain proteolysis|defense response to virus|positive regulation of killing of cells of other organism|positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity|positive regulation of fructose 1,6-bisphosphate metabolic process|positive regulation of vitamin D biosynthetic process|positive regulation of calcidiol 1-monooxygenase activity|cellular response to lipopolysaccharide|cellular response to interleukin-18|negative regulation of metanephric nephron tubule epithelial cell differentiation|extrinsic apoptotic signaling pathway|regulation of neuronal action potential|positive regulation of tumor necrosis factor (ligand) superfamily member 11 production|regulation of hepatocyte proliferation|",cytokine activity|interferon-gamma receptor binding|protein binding|,10,-0.1,0.0228,10,-0.2,1.05,-0.1,0.795,-0.795,0.676,0,0,-1.6,1.1
ENSMUSG00000058756,THRA,thyroid hormone receptor alpha,nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|cytosol|,"cartilage condensation|ossification|regulation of thyroid hormone mediated signaling pathway|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|learning or memory|regulation of heart contraction|female courtship behavior|response to cold|hormone-mediated signaling pathway|organ morphogenesis|positive regulation of myotube differentiation|negative regulation of RNA polymerase II transcriptional preinitiation complex assembly|erythrocyte differentiation|intracellular receptor signaling pathway|thyroid gland development|regulation of myeloid cell apoptotic process|cytoplasmic sequestering of transcription factor|steroid hormone mediated signaling pathway|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of female receptivity|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of lipid catabolic process|Type I pneumocyte differentiation|negative regulation of DNA-templated transcription, initiation|",steroid receptor RNA activator RNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|single-stranded RNA binding|single-stranded RNA binding|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|thyroid hormone receptor activity|thyroid hormone receptor activity|protein binding|transcription factor binding|zinc ion binding|TBP-class protein binding|protein domain specific binding|chromatin DNA binding|protein complex binding|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|intronic transcription regulatory region DNA binding|metal ion binding|protein heterodimerization activity|protein dimerization activity|thyroid hormone binding|,10,0.1,0.404,10,0.1,0.46,0.1,0.792,0.792,0.677,0,0,-0.8,1.9
ENSMUSG00000029455,ALDH2,"aldehyde dehydrogenase 2, mitochondrial",mitochondrion|mitochondrion|extracellular vesicular exosome|,metabolic process|negative regulation of apoptotic process|oxidation-reduction process|,"aldehyde dehydrogenase (NAD) activity|protein binding|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|identical protein binding|NADH binding|",10,-0.2,0.742,10,-0.8,0.712,-0.3,0.79,-0.79,0.677,0,0,-2,0.5
ENSMUSG00000034601,2700049A03RIK,RIKEN cDNA 2700049A03 gene,cytoplasm|centrosome|centrosome|cytoskeleton|ciliary basal body|,smoothened signaling pathway|cell projection organization|cilium assembly|cilium morphogenesis|regulation of establishment of protein localization|,protein binding|,10,0.2,0.951,10,0,0,0.2,0.779,0.779,0.679,0,0,-0.7,1.9
ENSMUSG00000029772,AHCYL2,S-adenosylhomocysteine hydrolase-like 2,cellular_component|,one-carbon metabolic process|,adenosylhomocysteinase activity|hydrolase activity|,10,0.2,1.23,10,0,0,0.1,0.778,0.778,0.68,0,0,-1.8,1.1
ENSMUSG00000063713,KLK1B24,kallikrein 1-related peptidase b24,nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.2,1.38,-0.1,0.776,-0.776,0.68,0,0,-1.9,0.7
ENSMUSG00000042115,KLHDC8A,kelch domain containing 8A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,1.51,0.1,0.774,0.774,0.68,0,0,-0.8,1.8
ENSMUSG00000040040,IFT88,intraflagellar transport 88,acrosomal membrane|outer acrosomal membrane|cytoplasm|trans-Golgi network|centrosome|centriole|cytoskeleton|cilium|cilium|axoneme|intraciliary transport particle B|motile primary cilium|photoreceptor connecting cilium|ciliary basal body|ciliary basal body|cell projection|apical part of cell|kinocilium|primary cilium|axonemal basal plate|ciliary tip|ciliary base|,eye development|kidney development|liver development|epithelial cell morphogenesis|Notch signaling pathway|smoothened signaling pathway|smoothened signaling pathway|sperm axoneme assembly|spermatid nucleus elongation|determination of left/right symmetry|nervous system development|brain development|brain development|heart development|protein localization|epidermis development|regulation of smoothened signaling pathway|organ morphogenesis|anterior/posterior pattern specification|dorsal/ventral pattern formation|spinal cord dorsal/ventral patterning|telencephalon development|cell projection organization|lung development|pancreas development|cytoplasmic microtubule organization|response to fluid shear stress|epidermal stem cell homeostasis|cilium assembly|regulation of odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|embryonic digit morphogenesis|positive regulation of insulin-like growth factor receptor signaling pathway|regulation of fat cell differentiation|forebrain morphogenesis|negative regulation of epithelial cell proliferation|cardiac muscle cell differentiation|palate development|inner ear receptor stereocilium organization|inner ear receptor stereocilium organization|limb development|cilium morphogenesis|cardiac septum morphogenesis|lung vasculature development|heart formation|regulation of protein processing|cochlea development|regulation of cilium assembly|regulation of autophagic vacuole assembly|,protein binding|kinesin binding|,10,-0.4,2.99,10,0.2,0.64,-0.3,0.772,-0.772,0.681,0,0,-1.5,1.2
ENSMUSG00000022847,THPO,thrombopoietin,extracellular region|extracellular space|,positive regulation of protein phosphorylation|cell proliferation|myeloid cell differentiation|thrombopoietin-mediated signaling pathway|positive regulation of megakaryocyte differentiation|positive regulation of protein kinase B signaling|positive regulation of ERK1 and ERK2 cascade|,receptor binding|cytokine activity|hormone activity|,10,0,0,10,0.2,1.2,0.1,0.763,0.763,0.682,0,0,-1.1,1.6
ENSMUSG00000029449,RHOF,"ras homolog gene family, member f",intracellular|cytoplasm|cytoskeleton|plasma membrane|membrane|extracellular vesicular exosome|,actin filament organization|small GTPase mediated signal transduction|,nucleotide binding|GTP binding|,10,0,0,10,-0.5,2.88,-0.2,0.762,-0.762,0.683,0,0,-1.9,0.4
ENSMUSG00000027876,REG4,"regenerating islet-derived family, member 4",extracellular region|extracellular space|cytoplasm|cytoplasm|,biological_process|,heparin binding|carbohydrate binding|mannan binding|,10,0.2,0.75,10,0.1,0.188,0.1,0.762,0.762,0.683,0,0,-1.3,1.5
ENSMUSG00000041974,SPIDR,scaffolding protein involved in DNA repair,nuclear chromosome|nucleus|,double-strand break repair via homologous recombination|DNA repair|DNA recombination|cellular response to DNA damage stimulus|regulation of double-strand break repair via homologous recombination|positive regulation of protein complex assembly|regulation of establishment of protein localization to chromosome|cellular response to ionizing radiation|cellular response to hydroxyurea|cellular response to camptothecin|positive regulation of double-strand break repair|,molecular_function|,10,0.8,0.673,10,-0.2,1.11,0.1,0.759,0.759,0.683,0,0,-0.8,1.9
ENSMUSG00000000486,1-Sep,septin 1,cytoplasm|cytoskeleton|septin complex|,cell cycle|cell division|,nucleotide binding|GTP binding|,10,0.4,1.75,10,-0.7,2.53,-0.6,0.758,-0.758,0.683,0,0,-1.8,1.2
ENSMUSG00000028212,CCNE2,cyclin E2,nucleus|,regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|DNA replication initiation|cell cycle|regulation of protein kinase activity|cell division|regulation of cell cycle|,cyclin-dependent protein serine/threonine kinase regulator activity|protein kinase binding|,10,0,0,10,-0.2,1.49,-0.1,0.756,-0.756,0.684,0,0,-1.7,1.3
ENSMUSG00000021253,TGFB3,"transforming growth factor, beta 3",extracellular region|extracellular space|nucleus|cytoplasm|cell surface|secretory granule|T-tubule|extracellular matrix|extracellular matrix|neuronal cell body|,"activation of MAPK activity|response to hypoxia|in utero embryonic development|transforming growth factor beta receptor signaling pathway|SMAD protein import into nucleus|negative regulation of DNA replication|negative regulation of cell proliferation|negative regulation of cell proliferation|embryo development|organ morphogenesis|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of macrophage cytokine production|cell growth|negative regulation of transforming growth factor beta receptor signaling pathway|mammary gland development|response to progesterone|positive regulation of collagen biosynthetic process|growth|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of neuron apoptotic process|response to estrogen|cell-cell junction organization|positive regulation of DNA replication|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|lung alveolus development|embryonic neurocranium morphogenesis|positive regulation of protein secretion|positive regulation of filopodium assembly|positive regulation of cell division|palate development|face morphogenesis|positive regulation of SMAD protein import into nucleus|detection of hypoxia|cellular response to growth factor stimulus|",type II transforming growth factor beta receptor binding|transforming growth factor beta receptor binding|growth factor activity|type I transforming growth factor beta receptor binding|identical protein binding|protein heterodimerization activity|transforming growth factor beta binding|,10,0,0,10,-0.2,1.37,-0.2,0.756,-0.756,0.684,0,0,-1.6,1.1
ENSMUSG00000022114,SPRY2,sprouty homolog 2 (Drosophila),cell|cytoplasm|cytoskeleton|microtubule|plasma membrane|membrane|cell projection|,establishment of mitotic spindle orientation|multicellular organismal development|sensory perception of sound|negative regulation of cell proliferation|regulation of signal transduction|positive regulation of gene expression|negative regulation of peptidyl-threonine phosphorylation|lung development|positive regulation of peptidyl-serine phosphorylation|negative regulation of Ras GTPase activity|negative regulation of fibroblast growth factor receptor signaling pathway|negative regulation of fibroblast growth factor receptor signaling pathway|inner ear morphogenesis|inner ear morphogenesis|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of MAP kinase activity|cell fate commitment|cell fate commitment|negative regulation of Ras protein signal transduction|branching morphogenesis of an epithelial tube|negative regulation of neurotrophin TRK receptor signaling pathway|positive regulation of protein kinase B signaling|lung morphogenesis|lung growth|bud elongation involved in lung branching|respiratory system development|negative regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of protein serine/threonine kinase activity|,protein binding|protein kinase binding|protein serine/threonine kinase activator activity|,10,-0.1,0.36,10,-0.1,0.464,-0.1,0.755,-0.755,0.684,0,0,-1.6,1.2
ENSMUSG00000028717,TAL1,T cell acute lymphocytic leukemia 1,histone deacetylase complex|nuclear chromatin|nucleus|nucleus|transcription factor complex|transcription factor complex|transcription factor complex|Lsd1/2 complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|locomotory behavior|spinal cord association neuron differentiation|hemopoiesis|myeloid cell differentiation|myeloid cell differentiation|cell differentiation|neuron differentiation|erythrocyte differentiation|erythrocyte differentiation|erythrocyte differentiation|megakaryocyte differentiation|platelet formation|positive regulation of protein complex assembly|embryonic hemopoiesis|megakaryocyte development|regulation of cell proliferation|erythrocyte maturation|cell fate commitment|regulation of myeloid cell differentiation|positive regulation of erythrocyte differentiation|positive regulation of erythrocyte differentiation|positive regulation of chromatin assembly or disassembly|positive regulation of transcription, DNA-templated|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|generation of neurons|positive regulation of cell division|astrocyte fate commitment|definitive hemopoiesis|hemangioblast cell differentiation|hematopoietic stem cell differentiation|regulation of mast cell differentiation|regulation of stem cell maintenance|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor binding|DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|enzyme binding|histone deacetylase binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|E-box binding|E-box binding|,10,0.2,0.569,10,-0.2,0.594,0.2,0.747,0.747,0.686,0,0,-1.3,1.4
ENSMUSG00000050332,AMER1,APC membrane recruitment 1,nucleus|cytoplasm|plasma membrane|membrane|,kidney development|Wnt signaling pathway|bone development|adipose tissue development|regulation of canonical Wnt signaling pathway|mesenchymal cell differentiation involved in kidney development|negative regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,"phosphatidylinositol-4,5-bisphosphate binding|beta-catenin binding|lipid binding|",10,0.1,0.477,10,0.1,0.333,0.1,0.743,0.743,0.687,0,0,-0.9,1.8
ENSMUSG00000090315,VMN2R104,"vomeronasal 2, receptor 104",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0.2,1.15,10,0.1,0.00694,0.2,0.739,0.739,0.687,0,0,-0.9,1.7
ENSMUSG00000046449,C77370,expressed sequence C77370,nucleus|delta DNA polymerase complex|,"mitotic S phase|base-excision repair, gap-filling|nucleotide-excision repair, DNA gap filling|multicellular organismal development|regulation of mitotic cell cycle|nervous system development|DNA replication, removal of RNA primer|DNA replication proofreading|DNA biosynthetic process|nucleic acid phosphodiester bond hydrolysis|",DNA-directed DNA polymerase activity|3'-5' exonuclease activity|,10,-0.6,2.77,10,0.1,0.0307,-0.4,0.735,-0.735,0.688,0,0,-1.9,0.7
ENSMUSG00000062762,EI24,etoposide induced 2.4 mRNA,intracellular|nucleus|cytoplasm|endoplasmic reticulum|membrane|membrane|integral component of membrane|,autophagy|apoptotic process|intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of cell growth|response to drug|neuromuscular process controlling balance|positive regulation of intrinsic apoptotic signaling pathway|,molecular_function|,10,-0.1,0.0103,10,-0.3,0.864,-0.2,0.734,-0.734,0.688,0,0,-1.8,0.8
ENSMUSG00000079434,NEU2,neuraminidase 2,cytoplasm|cytosol|,carbohydrate metabolic process|lipid metabolic process|ganglioside catabolic process|metabolic process|oligosaccharide catabolic process|positive regulation of myotube differentiation|lipid catabolic process|positive regulation of myoblast differentiation|,"exo-alpha-sialidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|exo-alpha-(2->3)-sialidase activity|exo-alpha-(2->6)-sialidase activity|exo-alpha-(2->8)-sialidase activity|",10,0.4,2.46,10,-0.1,0.0903,0.3,0.733,0.733,0.689,0,0,-0.8,1.8
ENSMUSG00000015243,ABCA1,"ATP-binding cassette, sub-family A (ABC1), member 1",Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|endocytic vesicle|high-density lipoprotein particle|intracellular membrane-bounded organelle|membrane raft|phagocytic vesicle|perinuclear region of cytoplasm|,"peptide secretion|ATP catabolic process|protein lipidation|transport|phagocytosis, engulfment|lysosome organization|G-protein coupled receptor signaling pathway|cholesterol metabolic process|cholesterol metabolic process|positive regulation of cholesterol efflux|phospholipid transport|endosomal transport|cholesterol transport|positive regulation of cAMP biosynthetic process|intracellular cholesterol transport|regulation of Cdc42 protein signal transduction|cholesterol efflux|cholesterol efflux|cholesterol efflux|phospholipid efflux|phospholipid efflux|phospholipid efflux|ion transmembrane transport|high-density lipoprotein particle assembly|apolipoprotein A-I-mediated signaling pathway|lipoprotein metabolic process|lipoprotein biosynthetic process|lipoprotein biosynthetic process|cholesterol homeostasis|reverse cholesterol transport|reverse cholesterol transport|phospholipid translocation|interleukin-1 beta secretion|transmembrane transport|phospholipid homeostasis|platelet dense granule organization|cellular response to lipopolysaccharide|cellular response to retinoic acid|","nucleotide binding|receptor binding|protein binding|ATP binding|phospholipid transporter activity|phospholipid transporter activity|phospholipid transporter activity|anion transmembrane transporter activity|ATPase activity|cholesterol transporter activity|cholesterol transporter activity|cholesterol transporter activity|syntaxin binding|small GTPase binding|apolipoprotein binding|apolipoprotein A-I binding|apolipoprotein A-I receptor activity|ATPase activity, coupled to transmembrane movement of substances|ATPase binding|",10,0,0,10,-0.2,1.05,-0.2,0.731,-0.731,0.689,0,0,-1.7,1
ENSMUSG00000026283,ING5,"inhibitor of growth family, member 5",nucleus|MOZ/MORF histone acetyltransferase complex|,"DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|protein acetylation|negative regulation of cell proliferation|negative regulation of cell proliferation|chromatin modification|histone acetylation|positive regulation of apoptotic process|histone H3 acetylation|positive regulation of transcription, DNA-templated|negative regulation of growth|positive regulation of apoptotic signaling pathway|",chromatin binding|chromatin binding|zinc ion binding|methylated histone binding|metal ion binding|,10,0,0,10,-0.3,1.73,-0.3,0.73,-0.73,0.689,0,0,-1.7,0.9
ENSMUSG00000000381,WAP,whey acidic protein,extracellular region|,negative regulation of peptidase activity|,peptidase inhibitor activity|nutrient reservoir activity|,10,0,0,10,0.2,1.11,0.1,0.725,0.725,0.69,0,0,-0.9,1.7
ENSMUSG00000017548,SUZ12,suppressor of zeste 12 homolog (Drosophila),sex chromatin|nucleus|nucleus|chromosome|ESC/E(Z) complex|ESC/E(Z) complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|chromatin modification|histone methylation|histone methylation|histone ubiquitination|negative regulation of cell differentiation|",chromatin binding|RNA binding|protein binding|methylated histone binding|histone methyltransferase activity|sequence-specific DNA binding|metal ion binding|,10,-0.3,1.59,10,0,0,-0.1,0.713,-0.713,0.693,0,0,-1.7,1
ENSMUSG00000023046,IGFBP6,insulin-like growth factor binding protein 6,extracellular region|extracellular space|cytoplasm|Golgi apparatus|extracellular vesicular exosome|,regulation of cell growth|,insulin-like growth factor binding|growth factor binding|insulin-like growth factor I binding|insulin-like growth factor II binding|,10,0.3,1.23,10,0,0,0.2,0.704,0.704,0.694,0,0,-0.7,1.8
ENSMUSG00000094601,GM5926,predicted gene 5926,cellular_component|,biological_process|,molecular_function|,1,0.1,0.0173,1,0.4,0.94,0.3,0.699,0.699,0.695,0,0,-1.7,2
ENSMUSG00000039410,PRDM16,PR domain containing 16,nucleus|nucleus|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|neurogenesis|cell differentiation|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of granulocyte differentiation|somatic stem cell maintenance|regulation of cellular respiration|tongue development|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|white fat cell differentiation|brown fat cell differentiation|brown fat cell differentiation|palate development|",nucleic acid binding|DNA binding|transcription coactivator activity|protein binding|sequence-specific DNA binding|sequence-specific DNA binding|SMAD binding|metal ion binding|,10,-0.6,3.4,10,0.1,0.0998,-0.4,0.699,-0.699,0.695,0,0,-1.9,0.7
ENSMUSG00000030595,NFKBIB,"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta",nucleus|cytoplasm|cytosol|,signal transduction|cytoplasmic sequestering of NF-kappaB|,protein binding|,10,0.5,3.43,10,0,0,0.5,0.697,0.697,0.696,0,0,-1,1.9
ENSMUSG00000049709,NLRP10,"NLR family, pyrin domain containing 10",cytoplasm|plasma membrane|membrane|extrinsic component of plasma membrane|,immune system process|positive regulation of T-helper 1 type immune response|defense response|helper T cell enhancement of adaptive immune response|dendritic cell migration|innate immune response|defense response to Gram-negative bacterium|defense response to fungus|positive regulation of T-helper 17 type immune response|positive regulation of interleukin-8 secretion|positive regulation of interleukin-6 secretion|,nucleotide binding|ATP binding|,10,0,0,10,-0.2,1.61,-0.1,0.695,-0.695,0.696,0,0,-1.6,1.1
ENSMUSG00000038146,NOTCH3,notch 3,nucleus|cytoplasm|plasma membrane|integral component of plasma membrane|actin cytoskeleton|membrane|integral component of membrane|receptor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|cell differentiation|forebrain development|negative regulation of cell differentiation|negative regulation of neuron differentiation|positive regulation of smooth muscle cell proliferation|neuron fate commitment|regulation of developmental process|",calcium ion binding|protein binding|enzyme binding|,10,0.3,0.587,10,0.2,0.205,0.2,0.695,0.695,0.696,0,0,-1.1,1.7
ENSMUSG00000005994,TYRP1,tyrosinase-related protein 1,endosome membrane|membrane|integral component of membrane|clathrin-coated endocytic vesicle membrane|melanosome membrane|melanosome|,melanin metabolic process|melanin biosynthetic process from tyrosine|metabolic process|melanocyte differentiation|melanosome organization|melanin biosynthetic process|acetoacetic acid metabolic process|pigmentation|oxidation-reduction process|,"monooxygenase activity|copper ion binding|protein binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen|6-hydroxy pseudo-oxynicotine monooxygenase activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|",10,0,0,10,0.5,1.86,0.1,0.693,0.693,0.696,0,0,-0.8,1.8
ENSMUSG00000031328,FLNA,"filamin, alpha",nucleus|cytoplasm|trans-Golgi network|cytosol|cytoskeleton|actin filament|plasma membrane|actin cytoskeleton|membrane|cortical cytoskeleton|Myb complex|neuronal cell body|dendritic shaft|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|apical dendrite|,epithelial to mesenchymal transition|adenylate cyclase-inhibiting dopamine receptor signaling pathway|cell projection organization|actin cytoskeleton organization|actin cytoskeleton reorganization|protein localization to cell surface|negative regulation of protein catabolic process|cilium assembly|mRNA transcription from RNA polymerase II promoter|positive regulation of transcription factor import into nucleus|receptor clustering|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of sequence-specific DNA binding transcription factor activity|early endosome to late endosome transport|establishment of protein localization|protein stabilization|cytoplasmic sequestering of protein|actin crosslink formation|spindle assembly involved in mitosis|,glycoprotein binding|actin binding|signal transducer activity|protein kinase C binding|protein binding|transcription factor binding|Rho GTPase binding|Ral GTPase binding|small GTPase binding|mu-type opioid receptor binding|Fc-gamma receptor I complex binding|protein homodimerization activity|poly(A) RNA binding|SMAD binding|Rac GTPase binding|actin filament binding|,10,0.1,0.192,10,0.1,0.56,0.1,0.69,0.69,0.697,0,0,-1,2
ENSMUSG00000024833,POLA2,"polymerase (DNA directed), alpha 2",nucleus|nucleus|alpha DNA polymerase:primase complex|cytoplasm|,"protein import into nucleus, translocation|DNA replication|DNA replication|DNA-dependent DNA replication|DNA replication initiation|DNA biosynthetic process|",DNA binding|DNA-directed DNA polymerase activity|protein binding|protein heterodimerization activity|,9,1.5,1.68,10,-0.5,0.633,1.3,0.687,0.687,0.698,0,0,-0.8,3
ENSMUSG00000035678,TNFSF9,"tumor necrosis factor (ligand) superfamily, member 9",extracellular space|plasma membrane|membrane|integral component of membrane|,immune response|positive regulation of interferon-gamma production|positive regulation of interleukin-12 production|positive regulation of interleukin-6 production|positive regulation of activated T cell proliferation|regulation of cell proliferation|myeloid dendritic cell differentiation|positive regulation of cytotoxic T cell differentiation|,receptor binding|cytokine activity|tumor necrosis factor receptor binding|tumor necrosis factor receptor superfamily binding|,10,0.1,0.273,10,0.1,0.475,0.1,0.686,0.686,0.698,0,0,-1.4,1.5
ENSMUSG00000016194,HSD11B1,hydroxysteroid 11-beta dehydrogenase 1,cytoplasm|endoplasmic reticulum|rough endoplasmic reticulum|membrane|membrane|integral component of membrane|nuclear membrane|intracellular membrane-bounded organelle|apical part of cell|,lipid metabolic process|glucocorticoid biosynthetic process|glucocorticoid catabolic process|metabolic process|steroid metabolic process|lung development|regulation of pentose-phosphate shunt|oxidation-reduction process|,11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity|11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity|11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity|steroid binding|oxidoreductase activity|NADP binding|11-beta-hydroxysteroid dehydrogenase (NADP+) activity|,10,0.1,0.348,10,-0.2,1.46,-0.2,0.685,-0.685,0.698,0,0,-1.5,1.2
ENSMUSG00000039943,PLCB4,"phospholipase C, beta 4",nucleus|cytoplasm|smooth endoplasmic reticulum|postsynaptic density|dendrite|,signal transduction|negative regulation of potassium ion transport|,signal transducer activity|protein binding|mitogen-activated protein kinase binding|,10,0.2,0.697,10,0.1,0.103,0.1,0.677,0.677,0.7,0,0,-1.1,1.6
ENSMUSG00000030994,D7ERTD443E,"DNA segment, Chr 7, ERATO Doi 443, expressed",cytoplasm|centrosome|cytoskeleton|actin cytoskeleton|,cellular response to DNA damage stimulus|mitotic G2 DNA damage checkpoint|response to UV|response to ionizing radiation|negative regulation of cell growth|protein stabilization|,histone deacetylase binding|,10,-0.4,1.54,10,0,0,-0.3,0.673,-0.673,0.701,0,0,-1.1,1.8
ENSMUSG00000063133,KLK1B1,kallikrein 1-related peptidase b1,nucleus|,tissue kallikrein-kinin cascade|bradykinin biosynthetic process|regulation of systemic arterial blood pressure|left ventricular cardiac muscle tissue morphogenesis|proteolysis|vasodilation|cardiac muscle contraction|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,0.644,10,-0.1,0.168,-0.1,0.673,-0.673,0.701,0,0,-1.6,1.1
ENSMUSG00000056429,TGOLN1,trans-golgi network protein,Golgi apparatus|trans-Golgi network|trans-Golgi network|plasma membrane|membrane|integral component of membrane|,None,None,10,-0.1,0.352,10,-0.3,0.492,-0.2,0.665,-0.665,0.702,0,0,-1.7,0.9
ENSMUSG00000021188,TRIP11,thyroid hormone receptor interactor 11,inner acrosomal membrane|acrosomal membrane|outer acrosomal membrane|nucleus|Golgi apparatus|cis-Golgi network|,ventricular septum development|,protein binding|,9,1.5,3.76,9,-0.9,2.24,1.4,0.661,0.661,0.703,0,0,-1.5,2.9
ENSMUSG00000029552,TES,testis derived transcript,nucleus|cytoplasm|cell junction|protein complex|,negative regulation of cell proliferation|regulation of cell proliferation|,zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,0.2,1.1,0.2,0.654,0.654,0.704,0,0,-1.7,1.3
ENSMUSG00000032402,SMAD3,SMAD family member 3,nuclear chromatin|intracellular|nucleus|nucleus|nuclear inner membrane|transcription factor complex|cytoplasm|cytoplasm|plasma membrane|protein complex|receptor complex|SMAD protein complex|SMAD2-SMAD3 protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|skeletal system development|osteoblast differentiation|response to hypoxia|in utero embryonic development|mesoderm formation|somitogenesis|liver development|negative regulation of protein phosphorylation|heart looping|osteoblast development|immune system development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transport|activation of cysteine-type endopeptidase activity involved in apoptotic process|immune response|cell cycle arrest|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|SMAD protein complex assembly|gastrulation|endoderm development|negative regulation of cell proliferation|embryonic pattern specification|positive regulation of alkaline phosphatase activity|positive regulation of epithelial to mesenchymal transition|regulation of striated muscle tissue development|regulation of transforming growth factor beta receptor signaling pathway|regulation of transforming growth factor beta receptor signaling pathway|evasion or tolerance of host defenses by virus|signal transduction involved in regulation of gene expression|negative regulation of cell growth|positive regulation of cell migration|positive regulation of bone mineralization|thyroid gland development|positive regulation of chondrocyte differentiation|positive regulation of interleukin-1 beta production|regulation of transforming growth factor beta2 production|positive regulation of transforming growth factor beta3 production|activin receptor signaling pathway|negative regulation of osteoblast proliferation|positive regulation of catenin import into nucleus|intracellular signal transduction|nodal signaling pathway|T cell activation|negative regulation of protein catabolic process|positive regulation of transcription factor import into nucleus|negative regulation of apoptotic process|cell-cell junction organization|negative regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|paraxial mesoderm morphogenesis|developmental growth|embryonic foregut morphogenesis|embryonic cranial skeleton morphogenesis|regulation of epithelial cell proliferation|negative regulation of inflammatory response|regulation of immune response|protein stabilization|positive regulation of positive chemotaxis|regulation of binding|positive regulation of stress fiber assembly|positive regulation of focal adhesion assembly|pericardium development|transdifferentiation|SMAD protein signal transduction|negative regulation of wound healing|lens fiber cell differentiation|positive regulation of canonical Wnt signaling pathway|extrinsic apoptotic signaling pathway|activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|positive regulation of gene expression involved in extracellular matrix organization|","core promoter proximal region sequence-specific DNA binding|protein binding transcription factor activity|RNA polymerase II activating transcription factor binding|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transforming growth factor beta receptor binding|protein binding|collagen binding|beta-catenin binding|transcription factor binding|transcription factor binding|zinc ion binding|enzyme binding|protein kinase binding|phosphatase binding|transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity|chromatin DNA binding|ubiquitin protein ligase binding|protein homodimerization activity|ubiquitin binding|bHLH transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|SMAD binding|metal ion binding|co-SMAD binding|R-SMAD binding|",10,0,0,10,0.3,1.22,0.1,0.654,0.654,0.704,0,0,-0.8,1.8
ENSMUSG00000024397,AIF1,allograft inflammatory factor 1,ruffle|phagocytic cup|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytoskeleton|actin filament|actin filament|plasma membrane|membrane|lamellipodium|lamellipodium|ruffle membrane|ruffle membrane|cell projection|perikaryon|perinuclear region of cytoplasm|,"microglial cell activation|positive regulation of protein phosphorylation|phagocytosis, engulfment|negative regulation of gene expression|positive regulation of muscle hyperplasia|Rac protein signal transduction|actin filament polymerization|positive regulation of cell migration|positive regulation of T cell proliferation|negative regulation of apoptotic process|positive regulation of nitric oxide biosynthetic process|positive regulation of smooth muscle cell proliferation|negative regulation of smooth muscle cell proliferation|actin filament bundle assembly|actin filament bundle assembly|negative regulation of smooth muscle cell chemotaxis|positive regulation of smooth muscle cell chemotaxis|positive regulation of monocyte chemotaxis|ruffle assembly|ruffle assembly|positive regulation of G1/S transition of mitotic cell cycle|positive regulation of T cell migration|",actin binding|calcium ion binding|protein binding|metal ion binding|actin filament binding|,10,-0.1,0.604,10,0.1,0.328,-0.1,0.654,-0.654,0.704,0,0,-1.5,1.3
ENSMUSG00000027793,CCNA1,cyclin A1,nucleus|cytoplasm|cytoskeleton|microtubule cytoskeleton|,regulation of cyclin-dependent protein serine/threonine kinase activity|cell cycle|mitotic nuclear division|meiotic nuclear division|multicellular organismal development|spermatogenesis|regulation of G2/M transition of mitotic cell cycle|cell differentiation|cell division|regulation of cell cycle|,protein binding|protein kinase binding|,10,-0.1,0.347,10,-0.1,0.365,-0.1,0.652,-0.652,0.705,0,0,-1.6,1.1
ENSMUSG00000003477,INMT,indolethylamine N-methyltransferase,cytoplasm|cytosol|cytosol|,amine metabolic process|response to toxic substance|methylation|methylation|,thioether S-methyltransferase activity|methyltransferase activity|transferase activity|amine N-methyltransferase activity|,10,0.3,0.278,10,0.2,0.441,0.2,0.651,0.651,0.705,0,0,-0.6,1.9
ENSMUSG00000024474,IK,IK cytokine,nucleus|,None,identical protein binding|,10,-1.4,2.99,10,0.1,0.562,-0.1,0.65,-0.65,0.705,0,0,-3,0.6
ENSMUSG00000029638,GLCCI1,glucocorticoid induced transcript 1,cytoplasm|,None,protein binding|,10,-0.3,2.18,10,0,0,-0.2,0.649,-0.649,0.705,0,0,-1.8,0.8
ENSMUSG00000073910,MOB3B,MOB kinase activator 3B,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.2,0.954,10,0,0,-0.1,0.647,-0.647,0.706,0,0,-1.7,1
ENSMUSG00000021065,FUT8,fucosyltransferase 8,cytoplasm|Golgi apparatus|membrane|membrane|integral component of membrane|Golgi cisterna membrane|extracellular vesicular exosome|,transforming growth factor beta receptor signaling pathway|integrin-mediated signaling pathway|respiratory gaseous exchange|cell migration|protein N-linked glycosylation via asparagine|protein glycosylation in Golgi|fucosylation|N-glycan fucosylation|receptor metabolic process|GDP-L-fucose metabolic process|,"glycoprotein 6-alpha-L-fucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|SH3 domain binding|alpha-(1->6)-fucosyltransferase activity|",10,-0.2,0.521,10,-0.1,0.335,-0.2,0.638,-0.638,0.708,0,0,-1.6,1.1
ENSMUSG00000002983,RELB,avian reticuloendotheliosis viral (v-rel) oncogene related B,nucleus|nucleus|cytoplasm|cytosol|cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of gene expression|antigen processing and presentation|NIK/NF-kappaB signaling|T-helper 1 type immune response|myeloid dendritic cell differentiation|T-helper 1 cell differentiation|cellular response to osmotic stress|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0.2,0.258,10,0.1,0.52,0.2,0.636,0.636,0.708,0,0,-1.3,1.5
ENSMUSG00000022707,GBE1,"glucan (1,4-alpha-), branching enzyme 1",extracellular vesicular exosome|,carbohydrate metabolic process|glycogen biosynthetic process|,"catalytic activity|1,4-alpha-glucan branching enzyme activity|hydrolase activity, hydrolyzing O-glycosyl compounds|transferase activity|transferase activity, transferring glycosyl groups|carbohydrate binding|cation binding|",10,1.4,2.7,10,-0.4,2.6,-0.3,0.635,-0.635,0.708,0,0,-1,2
ENSMUSG00000025480,SYCE1,synaptonemal complex central element protein 1,synaptonemal complex|central element|nucleus|chromosome|,cell cycle|meiotic nuclear division|meiotic prophase I|synaptonemal complex assembly|cell division|synaptonemal complex organization|,protein binding|,10,0.5,2.84,10,0,0,0.2,0.63,0.63,0.709,0,0,-0.5,1.9
ENSMUSG00000017897,EYA2,eyes absent 2 homolog (Drosophila),nucleus|cytoplasm|cytoplasm|mitochondrion|centrosome|,"DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein dephosphorylation|cellular response to DNA damage stimulus|multicellular organismal development|striated muscle tissue development|chromatin modification|histone dephosphorylation|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|extrinsic apoptotic signaling pathway in absence of ligand|mitochondrial outer membrane permeabilization|",magnesium ion binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|metal ion binding|,10,0.2,1.11,10,0,0,0.1,0.629,0.629,0.71,0,0,-0.9,1.8
ENSMUSG00000078773,RAD54B,RAD54 homolog B (S. cerevisiae),None,double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|ATP catabolic process|cellular response to DNA damage stimulus|response to ionizing radiation|response to drug|,DNA translocase activity|,10,0,0,10,0.1,0.731,0.1,0.62,0.62,0.711,0,0,-1.2,1.6
ENSMUSG00000025278,FLNB,"filamin, beta",stress fiber|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|extracellular vesicular exosome|,skeletal muscle tissue development|,actin binding|protein binding|identical protein binding|poly(A) RNA binding|,10,0,0,10,-0.1,0.705,-0.1,0.618,-0.618,0.712,0,0,-1.5,1.3
ENSMUSG00000026587,ASTN1,astrotactin 1,endosome|external side of plasma membrane|membrane|integral component of membrane|,neuron migration|neuron migration|cell adhesion|neuron cell-cell adhesion|locomotory behavior|single organismal cell-cell adhesion|cell migration|,protein binding|,10,0.2,1.92,10,0,0,0.1,0.617,0.617,0.712,0,0,-0.9,1.8
ENSMUSG00000024927,RELA,v-rel reticuloendotheliosis viral oncogene homolog A (avian),nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytosol|cytosol|protein complex|NF-kappaB complex|,"negative regulation of transcription from RNA polymerase II promoter|liver development|hair follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|defense response|inflammatory response|positive regulation of cell proliferation|response to bacterium|organ morphogenesis|response to organic substance|response to UV-B|positive regulation of Schwann cell differentiation|cytokine-mediated signaling pathway|positive regulation of chondrocyte differentiation|response to muramyl dipeptide|negative regulation of protein catabolic process|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of interleukin-12 biosynthetic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of insulin receptor signaling pathway|regulation of inflammatory response|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|cellular response to hydrogen peroxide|nucleotide-binding oligomerization domain containing 2 signaling pathway|response to interleukin-1|cellular response to nicotine|cellular response to interleukin-1|cellular response to interleukin-6|cellular response to tumor necrosis factor|cellular response to peptide hormone stimulus|positive regulation of miRNA metabolic process|negative regulation of extrinsic apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|enzyme binding|protein kinase binding|protein kinase binding|ubiquitin protein ligase binding|protein complex binding|activating transcription factor binding|phosphate ion binding|identical protein binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein N-terminus binding|NF-kappaB binding|repressing transcription factor binding|ankyrin repeat binding|,10,0.1,0.164,10,0.1,0.507,0.1,0.615,0.615,0.713,0,0,-1,1.7
ENSMUSG00000024293,ESCO1,establishment of cohesion 1 homolog 1 (S. cerevisiae),chromatin|nucleus|chromosome|,regulation of DNA replication|cell cycle|sister chromatid cohesion|post-translational protein acetylation|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|metal ion binding|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,-1.3,1.67,10,-0.1,0.573,-0.1,0.614,-0.614,0.713,0,0,-2,0.5
ENSMUSG00000025746,IL6,interleukin 6,extracellular region|extracellular space|extracellular space|cell|cytoplasm|interleukin-6 receptor complex|external side of plasma membrane|,"neutrophil apoptotic process|neutrophil apoptotic process|neutrophil apoptotic process|hepatic immune response|positive regulation of acute inflammatory response|negative regulation of protein kinase activity|acute-phase response|inflammatory response|immune response|positive regulation of cell proliferation|negative regulation of cell proliferation|regulation of cell shape|response to wounding|regulation of vascular endothelial growth factor production|positive regulation of gene expression|cell growth|cytokine-mediated signaling pathway|endocrine pancreas development|neuron projection development|positive regulation of chemokine production|positive regulation of interleukin-6 production|negative regulation of collagen biosynthetic process|positive regulation of peptidyl-serine phosphorylation|positive regulation of protein import into nucleus, translocation|positive regulation of T cell proliferation|T cell activation|regulation of cell proliferation|positive regulation of tyrosine phosphorylation of Stat3 protein|defense response to protozoan|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of MAPK cascade|negative regulation of chemokine biosynthetic process|negative regulation of chemokine biosynthetic process|regulation of circadian sleep/wake cycle, non-REM sleep|positive regulation of nitric oxide biosynthetic process|cell redox homeostasis|positive regulation of T-helper 2 cell differentiation|positive regulation of neuron differentiation|negative regulation of gluconeogenesis|positive regulation of translation|positive regulation of DNA replication|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JAK-STAT cascade|muscle cell cellular homeostasis|negative regulation of hormone secretion|negative regulation of muscle organ development|positive regulation of smooth muscle cell proliferation|positive regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|negative regulation of cytokine secretion|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of B cell activation|positive regulation of immunoglobulin secretion|positive regulation of sequence-specific DNA binding transcription factor activity|response to glucocorticoid|defense response to virus|positive regulation of protein kinase B signaling|positive regulation of transmission of nerve impulse|branching involved in salivary gland morphogenesis|branching involved in salivary gland morphogenesis|epithelial cell proliferation involved in salivary gland morphogenesis|glucagon secretion|interleukin-6-mediated signaling pathway|interleukin-6-mediated signaling pathway|cellular response to hydrogen peroxide|positive regulation of ERK1 and ERK2 cascade|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|T-helper 17 cell lineage commitment|negative regulation of neuron death|",receptor binding|cytokine activity|cytokine activity|interleukin-6 receptor binding|interleukin-6 receptor binding|interleukin-6 receptor binding|protein binding|growth factor activity|,10,-0.3,1.4,10,0,0,-0.2,0.614,-0.614,0.713,0,0,-1.8,0.7
ENSMUSG00000036585,FGF1,fibroblast growth factor 1,extracellular region|extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|nucleus|nucleolus|cytoplasm|cytosol|,"angiogenesis|organ induction|positive regulation of protein phosphorylation|multicellular organismal development|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|cell differentiation|lung development|positive regulation of cell migration|cellular response to heat|positive regulation of cholesterol biosynthetic process|positive regulation of angiogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of epithelial cell proliferation|positive regulation of cell division|cardiac muscle cell proliferation|branch elongation involved in ureteric bud branching|vasculogenesis involved in coronary vascular morphogenesis|mesonephric epithelium development|positive regulation of intracellular signal transduction|",receptor binding|fibroblast growth factor receptor binding|protein binding|growth factor activity|heparin binding|Hsp70 protein binding|S100 protein binding|,10,0.1,0.0642,10,-0.4,1.68,-0.1,0.614,-0.614,0.713,0,0,-1.4,1.6
ENSMUSG00000011831,EVI5,ecotropic viral integration site 5,nucleus|cytoplasm|Golgi apparatus|cytoskeleton|intracellular membrane-bounded organelle|,cell cycle|regulation of Rab GTPase activity|cell division|,Rab GTPase activator activity|,10,0.3,0.497,10,-0.2,0.78,0.2,0.611,0.611,0.714,0,0,-1,1.7
ENSMUSG00000015342,XK,Kell blood group precursor (McLeod phenotype) homolog,membrane|integral component of membrane|,transport|amino acid transport|,None,10,0,0,10,-0.4,2.97,-0.3,0.61,-0.61,0.714,0,0,-1.6,1.3
ENSMUSG00000022382,WNT7B,"wingless-type MMTV integration site family, member 7B",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|cytoplasm|plasma membrane|cell surface|,in utero embryonic development|vasculature development|metanephros morphogenesis|signal transduction|signal transduction|activation of JUN kinase activity|cell-cell signaling|multicellular organismal development|positive regulation of cell proliferation|positive regulation of gene expression|Wnt signaling pathway|Wnt signaling pathway|establishment or maintenance of polarity of embryonic epithelium|cell proliferation in forebrain|central nervous system vasculogenesis|neuron differentiation|lung development|neuron projection development|oxygen homeostasis|regulation of cell projection size|odontogenesis of dentin-containing tooth|homeostatic process|cellular metabolic process|cell fate commitment|positive regulation of osteoblast differentiation|negative regulation of smoothened signaling pathway|positive regulation of JNK cascade|positive regulation of JNK cascade|embryonic organ development|neuron projection morphogenesis|stem cell development|negative regulation of neurogenesis|synapse organization|smooth muscle cell differentiation|anatomical structure regression|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|lung morphogenesis|lung epithelium development|lobar bronchus development|lung-associated mesenchyme development|trachea cartilage morphogenesis|developmental growth involved in morphogenesis|embryonic placenta morphogenesis|chorio-allantoic fusion|renal inner medulla development|renal outer medulla development|outer medullary collecting duct development|inner medullary collecting duct development|metanephric collecting duct development|metanephric epithelium development|metanephric loop of Henle development|apoptotic process involved in patterning of blood vessels|positive regulation of receptor activity|,receptor binding|frizzled binding|protein binding|receptor agonist activity|,10,0.1,0.186,10,0.1,0.478,0.1,0.608,0.608,0.714,0,0,-1,1.7
ENSMUSG00000072720,MYO18B,myosin XVIIIb,myosin complex|unconventional myosin complex|Z disc|filamentous actin|,vasculogenesis|in utero embryonic development|cardiac muscle fiber development|,nucleotide binding|molecular_function|ATP binding|,10,0.1,0.729,10,0,0,0.1,0.605,0.605,0.715,0,0,-1.1,1.6
ENSMUSG00000021285,PPP1R13B,"protein phosphatase 1, regulatory (inhibitor) subunit 13B",nucleus|cytoplasm|plasma membrane|,apoptotic process|negative regulation of cell cycle|intrinsic apoptotic signaling pathway by p53 class mediator|,transcription factor binding|,10,0.5,3.01,10,0,0,0.4,0.603,0.603,0.715,0,0,-0.4,2
ENSMUSG00000039005,TLR4,toll-like receptor 4,cytoplasm|plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|membrane raft|lipopolysaccharide receptor complex|perinuclear region of cytoplasm|,activation of MAPK activity|microglial cell activation|activation of innate immune response|toll-like receptor signaling pathway|B cell proliferation involved in immune response|immune system process|nitric oxide production involved in inflammatory response|MyD88-dependent toll-like receptor signaling pathway|innate immune response-activating signal transduction|leukotriene metabolic process|inflammatory response|immune response|response to oxidative stress|signal transduction|activation of NF-kappaB-inducing kinase activity|I-kappaB phosphorylation|response to bacterium|positive regulation of platelet activation|positive regulation of B cell proliferation|lipopolysaccharide-mediated signaling pathway|lipopolysaccharide-mediated signaling pathway|lipopolysaccharide-mediated signaling pathway|response to lipopolysaccharide|response to lipopolysaccharide|response to lipopolysaccharide|detection of lipopolysaccharide|detection of lipopolysaccharide|interferon-gamma production|negative regulation of interferon-gamma production|negative regulation of interleukin-17 production|negative regulation of interleukin-23 production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|positive regulation of chemokine production|positive regulation of chemokine production|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|positive regulation of interferon-gamma production|positive regulation of interleukin-1 production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of stress-activated MAPK cascade|toll-like receptor 4 signaling pathway|macrophage activation|macrophage activation|positive regulation of NF-kappaB import into nucleus|positive regulation of tumor necrosis factor biosynthetic process|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of DNA binding|positive regulation of interleukin-12 biosynthetic process|innate immune response|positive regulation of MHC class II biosynthetic process|positive regulation of interferon-beta biosynthetic process|positive regulation of interleukin-1 biosynthetic process|positive regulation of interleukin-13 biosynthetic process|positive regulation of interleukin-6 biosynthetic process|positive regulation of interleukin-8 biosynthetic process|positive regulation of nitric oxide biosynthetic process|response to ethanol|mast cell activation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|positive regulation of JNK cascade|positive regulation of lymphocyte proliferation|regulation of cytokine secretion|regulation of inflammatory response|positive regulation of inflammatory response|positive regulation of peptidyl-tyrosine phosphorylation|defense response to Gram-negative bacterium|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of nitric-oxide synthase biosynthetic process|regulation of sensory perception of pain|intestinal epithelial structure maintenance|positive regulation of macrophage cytokine production|negative regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway|positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway|response to fatty acid|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|cellular response to lipoteichoic acid|,lipopolysaccharide binding|lipopolysaccharide receptor activity|receptor activity|transmembrane signaling receptor activity|protein binding|phosphatidylinositol 3-kinase binding|,10,-0.3,0.801,10,0.1,0.483,0.1,0.603,0.603,0.715,0,0,-1.6,1.2
ENSMUSG00000041566,TSSK1,testis-specific serine kinase 1,acrosomal vesicle|cytoplasm|cytoplasmic vesicle|motile cilium|cell projection|,protein phosphorylation|multicellular organismal development|spermatogenesis|spermatid development|phosphorylation|cell differentiation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.2,0.464,10,0.5,0.647,0.2,0.6,0.6,0.716,0,0,-0.7,1.8
ENSMUSG00000024653,SCGB1A1,"secretoglobin, family 1A, member 1 (uteroglobin)",extracellular region|extracellular space|intracellular|nuclear envelope|cytoplasm|cytoplasm|endoplasmic reticulum|rough endoplasmic reticulum|secretory granule|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of interferon-gamma production|negative regulation of interleukin-13 production|negative regulation of interleukin-13 production|negative regulation of interleukin-4 production|negative regulation of interleukin-4 production|negative regulation of interleukin-5 production|negative regulation of interleukin-5 production|response to cytokine|negative regulation of T cell proliferation|regulation of mRNA stability|regulation of inflammatory response|,phospholipase A2 inhibitor activity|,10,-0.7,0.494,10,0.4,2.74,0.2,0.599,0.599,0.716,0,0,-1.6,1.4
ENSMUSG00000024201,KDM4B,lysine (K)-specific demethylase 4B,nucleus|focal adhesion|cell junction|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|oxidation-reduction process|","sulfonate dioxygenase activity|zinc ion binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.1,0.304,10,0.1,0.337,0.1,0.586,0.586,0.719,0,0,-1.1,1.7
ENSMUSG00000078249,HMGA1-RS1,"high mobility group AT-hook I, related sequence 1",nucleus|senescence-associated heterochromatin focus|,"DNA catabolic process, endonucleolytic|regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|DNA-(apurinic or apyrimidinic site) lyase activity|transcription factor binding|enzyme binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoic acid receptor binding|peroxisome proliferator activated receptor binding|retinoid X receptor binding|5'-deoxyribose-5-phosphate lyase activity|,8,0.9,2.53,8,0.1,0.223,0.1,0.584,0.584,0.72,0,0,-0.4,2
ENSMUSG00000029176,ANAPC4,anaphase promoting complex subunit 4,nucleus|anaphase-promoting complex|,cell cycle|mitotic nuclear division|regulation of mitotic metaphase/anaphase transition|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell division|protein K11-linked ubiquitination|,protein phosphatase binding|,9,0.6,2.22,10,0.1,0.138,-0.1,0.578,-0.578,0.721,0,0,-0.8,1.9
ENSMUSG00000049811,FAM161A,"family with sequence similarity 161, member A",cytoplasm|centrosome|cytoskeleton|cilium|photoreceptor connecting cilium|photoreceptor connecting cilium|ciliary basal body|ciliary basal body|cell projection|,cell projection organization|cilium assembly|,molecular_function|,10,0,0,10,0.2,1.05,0.1,0.577,0.577,0.721,0,0,-1.5,1.5
ENSMUSG00000036192,RORB,RAR-related orphan receptor beta,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|G-protein coupled receptor signaling pathway|multicellular organismal development|visual perception|amacrine cell differentiation|eye photoreceptor cell development|regulation of circadian rhythm|steroid hormone mediated signaling pathway|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|retinal rod cell development|retinal cone cell development|rhythmic process|response to stimulus|retina development in camera-type eye|cellular response to retinoic acid|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|transcription factor binding|zinc ion binding|melatonin receptor activity|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0.3,2.4,0.3,0.574,0.574,0.722,0,0,-0.5,2
ENSMUSG00000043384,GPRASP1,G protein-coupled receptor associated sorting protein 1,nucleus|cytoplasm|,endosome to lysosome transport|G-protein coupled receptor catabolic process|,protein binding|,10,-0.3,1.54,10,0,0,-0.2,0.573,-0.573,0.722,0,0,-1.4,1.6
ENSMUSG00000031595,PDGFRL,platelet-derived growth factor receptor-like,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.1,0.421,10,0.2,0.223,0.2,0.572,0.572,0.722,0,0,-0.7,1.9
ENSMUSG00000070469,ADAMTSL3,ADAMTS-like 3,cellular_component|,biological_process|,molecular_function|,10,0.9,2.1,10,0.1,0.0723,0.1,0.572,0.572,0.722,0,0,-0.6,2
ENSMUSG00000039298,CDK5RAP2,CDK5 regulatory subunit associated protein 2,pericentriolar material|spindle pole|cell|cytoplasm|Golgi apparatus|centrosome|centrosome|cytoskeleton|microtubule|cell junction|perinuclear region of cytoplasm|extracellular vesicular exosome|,"establishment of mitotic spindle orientation|microtubule cytoskeleton organization|microtubule bundle formation|chromosome segregation|brain development|neurogenesis|negative regulation of neuron differentiation|positive regulation of transcription, DNA-templated|negative regulation of centriole replication|centrosome organization|regulation of spindle checkpoint|",protein binding|calmodulin binding|microtubule binding|tubulin binding|protein kinase binding|protein complex binding|transcription regulatory region DNA binding|,10,0.4,0.187,10,0.1,0.799,0.1,0.568,0.568,0.723,0,0,-1,1.7
ENSMUSG00000020321,MDH1,"malate dehydrogenase 1, NAD (soluble)",extracellular space|cytoplasm|mitochondrion|centrosome|cytosol|extracellular vesicular exosome|,carbohydrate metabolic process|tricarboxylic acid cycle|oxaloacetate metabolic process|malate metabolic process|NADH metabolic process|NAD metabolic process|cellular carbohydrate metabolic process|oxidation-reduction process|,"catalytic activity|oxidoreductase activity|malate dehydrogenase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|L-malate dehydrogenase activity|NAD binding|",10,0,0,10,0.2,0.739,0.1,0.567,0.567,0.723,0,0,-1.1,1.7
ENSMUSG00000022434,FAM118A,"family with sequence similarity 118, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.56,10,-0.1,0.0261,0.2,0.565,0.565,0.724,0,0,-0.9,1.8
ENSMUSG00000020865,ABCC3,"ATP-binding cassette, sub-family C (CFTR/MRP), member 3",integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,ATP catabolic process|transport|drug transmembrane transport|lipid transport|canalicular bile acid transport|drug transport|ion transmembrane transport|xenobiotic transport|transmembrane transport|,"nucleotide binding|transporter activity|ATP binding|xenobiotic-transporting ATPase activity|drug transmembrane transporter activity|bile acid-exporting ATPase activity|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,0,0,10,-0.4,2.35,-0.1,0.563,-0.563,0.724,0,0,-1.8,0.8
ENSMUSG00000025056,NR0B1,"nuclear receptor subfamily 0, group B, member 1",nucleus|nucleus|cytoplasm|cytoplasm|membrane|polysomal ribosome|polysomal ribosome|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|steroid biosynthetic process|spermatogenesis|sex determination|protein localization|gonad development|male gonad development|male gonad development|cell differentiation|male sex determination|male sex determination|adrenal gland development|adrenal gland development|intracellular receptor signaling pathway|negative regulation of intracellular steroid hormone receptor signaling pathway|Leydig cell differentiation|response to immobilization stress|steroid hormone mediated signaling pathway|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|Sertoli cell differentiation|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|transcription corepressor activity|transcription corepressor activity|RNA binding|RNA binding|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|transcription factor binding|protein domain specific binding|DNA hairpin binding|steroid hormone receptor binding|protein homodimerization activity|sequence-specific DNA binding|AF-2 domain binding|,10,-0.1,0.0693,10,-0.2,0.618,-0.1,0.562,-0.562,0.725,0,0,-1.1,1.7
ENSMUSG00000079334,NAT6,N-acetyltransferase 6,cytoplasm|,biological_process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",9,0.1,0.324,9,0.3,0.695,0.2,0.551,0.551,0.727,0,0,-1.2,1.6
ENSMUSG00000041193,PLA2G5,"phospholipase A2, group V",extracellular region|Golgi apparatus|plasma membrane|cell surface|membrane|perinuclear region of cytoplasm|,lipid metabolic process|phospholipid metabolic process|platelet activating factor biosynthetic process|lipid catabolic process|leukotriene biosynthetic process|arachidonic acid secretion|arachidonic acid secretion|,phospholipase A2 activity|receptor binding|calcium ion binding|heparin binding|hydrolase activity|metal ion binding|calcium-dependent phospholipase A2 activity|,10,0.2,0.546,10,-0.1,0.502,-0.1,0.544,-0.544,0.729,0,0,-1.3,1.5
ENSMUSG00000028453,FANCG,"Fanconi anemia, complementation group G",nucleus|nucleolus|cytoplasm|mitochondrion|plasma membrane|Fanconi anaemia nuclear complex|,ovarian follicle development|DNA repair|cellular response to DNA damage stimulus|mitochondrion organization|spermatid development|response to radiation|,None,9,0.2,1.74,9,0,0,0.1,0.54,0.54,0.73,0,0,-0.9,1.9
ENSMUSG00000002058,UNC119,unc-119 homolog (C. elegans),spindle pole|cytoplasm|centrosome|cytoskeleton|intercellular bridge|spindle midzone|,"transport|cytokinesis, completion of separation|visual perception|protein transport|lipoprotein transport|lipoprotein transport|response to stimulus|positive regulation of protein tyrosine kinase activity|negative regulation of clathrin-mediated endocytosis|negative regulation of caveolin-mediated endocytosis|",protein binding|lipid binding|,10,0.1,0.458,10,0.1,0.131,0.1,0.539,0.539,0.73,0,0,-1.1,1.7
ENSMUSG00000035781,R3HDM4,R3H domain containing 4,cellular_component|nucleus|,biological_process|,molecular_function|nucleic acid binding|,10,0.3,0.0874,10,-0.6,2.43,-0.5,0.535,-0.535,0.731,0,0,-1.9,0.9
ENSMUSG00000061046,HAGHL,hydroxyacylglutathione hydrolase-like,cellular_component|,glutathione biosynthetic process|biological_process|,"molecular_function|hydroxyacylglutathione hydrolase activity|zinc ion binding|CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|metal ion binding|acyl-CoA hydrolase activity|",10,0,0,10,0.3,1.4,0.2,0.535,0.535,0.731,0,0,-1,1.7
ENSMUSG00000054136,ADM2,adrenomedullin 2,extracellular region|,angiogenesis|protein phosphorylation|adenylate cyclase-activating G-protein coupled receptor signaling pathway|digestion|feeding behavior|positive regulation of gene expression|positive regulation of angiogenesis|negative regulation of blood pressure|,hormone activity|protein complex binding|,10,0.4,2.47,10,-0.1,0.58,0.3,0.534,0.534,0.731,0,0,-0.9,1.7
ENSMUSG00000023930,CRISP2,cysteine-rich secretory protein 2,extracellular region|,single organismal cell-cell adhesion|,None,10,0,0,10,0.3,1.75,0.2,0.533,0.533,0.731,0,0,-0.9,1.7
ENSMUSG00000043051,DISC1,disrupted in schizophrenia 1,nucleus|cytoplasm|mitochondrion|mitochondrion|endoplasmic reticulum|centrosome|centrosome|centrosome|cytoskeleton|kinesin complex|microtubule|plasma membrane|membrane|cell junction|dynein complex|axon|ciliary basal body|cell body|synapse|postsynaptic membrane|perinuclear region of cytoplasm|,microtubule cytoskeleton organization|neuron migration|neuron migration|positive regulation of cell-matrix adhesion|positive regulation of neuroblast proliferation|positive regulation of neuroblast proliferation|multicellular organismal development|nervous system development|protein localization|regulation of neuron projection development|regulation of neuron projection development|positive regulation of neuron projection development|Wnt signaling pathway|cerebral cortex radially oriented cell migration|cell proliferation in forebrain|pyramidal neuron migration|positive regulation of Wnt signaling pathway|positive regulation of Wnt signaling pathway|TOR signaling|cellular protein localization|cilium assembly|positive regulation of axon extension|mitochondrial calcium ion homeostasis|canonical Wnt signaling pathway|regulation of dendritic spine development|regulation of synapse maturation|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,protein binding|kinesin binding|protein complex binding|,10,0.3,2.03,10,0,0,0.2,0.531,0.531,0.732,0,0,-1,1.7
ENSMUSG00000027695,PLD1,phospholipase D1,cytoplasm|lysosomal membrane|endosome|endoplasmic reticulum|Golgi apparatus|membrane|membrane|lamellipodium|vesicle|Golgi cisterna|intracellular membrane-bounded organelle|,lipid metabolic process|phosphatidic acid biosynthetic process|metabolic process|phospholipid biosynthetic process|phospholipid catabolic process|lipid catabolic process|positive regulation of cell migration|response to peptide hormone|defense response to Gram-positive bacterium|,catalytic activity|phospholipase D activity|hydrolase activity|phosphatidylinositol binding|N-acylphosphatidylethanolamine-specific phospholipase D activity|,10,0,0,10,-0.2,0.951,-0.2,0.521,-0.521,0.734,0,0,-1.7,1
ENSMUSG00000019966,KITL,kit ligand,extracellular region|extracellular space|cytoplasm|cytoskeleton|plasma membrane|membrane|integral component of membrane|,ovarian follicle development|neural crest cell migration|positive regulation of myeloid leukocyte differentiation|cell adhesion|germ cell development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of mast cell apoptotic process|embryonic hemopoiesis|ectopic germ cell programmed cell death|negative regulation of apoptotic process|positive regulation of MAP kinase activity|positive regulation of melanocyte differentiation|positive regulation of DNA replication|positive regulation of Ras protein signal transduction|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of mast cell proliferation|extrinsic apoptotic signaling pathway in absence of ligand|,cytokine activity|stem cell factor receptor binding|protein binding|growth factor activity|,10,0,0,10,0.1,0.955,0.1,0.516,0.516,0.736,0,0,-0.9,1.8
ENSMUSG00000045438,COX19,cytochrome c oxidase assembly protein 19,cytoplasm|,biological_process|,molecular_function|,10,-0.5,0.986,10,0.9,0.133,-0.2,0.515,-0.515,0.736,0,0,-1.2,1.9
ENSMUSG00000036461,ELF1,E74-like factor 1,nucleus|nucleus|,"regulation of cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of T cell receptor signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.4,1.09,10,0.1,0.0266,0.3,0.513,0.513,0.736,0,0,-0.7,1.9
ENSMUSG00000036073,GALT,galactose-1-phosphate uridyl transferase,Golgi apparatus|,carbohydrate metabolic process|galactose metabolic process|galactose metabolic process|UDP-glucose catabolic process|,catalytic activity|UDP-glucose:hexose-1-phosphate uridylyltransferase activity|UDP-glucose:hexose-1-phosphate uridylyltransferase activity|zinc ion binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,0,0,10,-0.2,1.8,-0.1,0.513,-0.513,0.736,0,0,-1.8,0.9
ENSMUSG00000016349,EEF1A2,eukaryotic translation elongation factor 1 alpha 2,nucleus|cytoplasm|eukaryotic translation elongation factor 1 complex|neuronal cell body|,translation|translational elongation|positive regulation of apoptotic process|,nucleotide binding|translation elongation factor activity|GTPase activity|GTP binding|,10,0.3,1.88,10,0,0,0.2,0.513,0.513,0.736,0,0,-1.1,1.7
ENSMUSG00000018965,YWHAH,"tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide",cytoplasm|plasma membrane|intercalated disc|extracellular vesicular exosome|,"regulation of sodium ion transport|regulation of sodium ion transport|glucocorticoid catabolic process|intracellular protein transport|cytoskeleton organization|regulation of mitosis|glucocorticoid receptor signaling pathway|negative regulation of apoptotic process|positive regulation of transcription, DNA-templated|negative regulation of dendrite morphogenesis|membrane depolarization during action potential|membrane depolarization during action potential|regulation of sodium ion transmembrane transporter activity|regulation of sodium ion transmembrane transporter activity|",actin binding|protein binding|sodium channel regulator activity|sodium channel regulator activity|enzyme binding|protein domain specific binding|glucocorticoid receptor binding|ion channel binding|ion channel binding|protein heterodimerization activity|,10,0.3,1.36,10,0,0,0.3,0.507,0.507,0.738,0,0,-0.8,1.8
ENSMUSG00000066090,INSL5,insulin-like 5,extracellular region|,None,hormone activity|,10,0,0,10,-0.2,1.17,-0.1,0.506,-0.506,0.738,0,0,-1.8,1
ENSMUSG00000054843,ATRNL1,attractin like 1,cellular_component|plasma membrane|membrane|integral component of membrane|,G-protein coupled receptor signaling pathway|multicellular organismal development|,receptor activity|protein binding|carbohydrate binding|,10,0.1,0.149,10,0.3,1.02,0.2,0.505,0.505,0.738,0,0,-0.5,2
ENSMUSG00000031133,ARHGEF6,Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6,cell-cell junction|lamellipodium|cell projection|,lamellipodium assembly|regulation of Rho protein signal transduction|intracellular signal transduction|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|,10,0,0,10,-0.2,1.22,-0.1,0.505,-0.505,0.738,0,0,-1.7,1.1
ENSMUSG00000014599,CSF1,colony stimulating factor 1 (macrophage),extracellular region|extracellular space|plasma membrane|membrane|integral component of membrane|receptor complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,ossification|positive regulation of cell-matrix adhesion|osteoclast proliferation|immune system process|developmental process involved in reproduction|inflammatory response|cell proliferation|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of macrophage derived foam cell differentiation|macrophage differentiation|regulation of ossification|osteoclast differentiation|positive regulation of cell migration|positive regulation of cellular protein metabolic process|positive regulation of mononuclear cell proliferation|positive regulation of multicellular organism growth|odontogenesis|positive regulation of odontogenesis of dentin-containing tooth|innate immune response|positive regulation of macrophage differentiation|positive regulation of macrophage differentiation|positive regulation of monocyte differentiation|positive regulation of osteoclast differentiation|positive regulation of osteoclast differentiation|positive regulation of osteoclast differentiation|positive regulation of osteoclast differentiation|positive regulation of protein kinase activity|positive regulation of Ras protein signal transduction|homeostasis of number of cells within a tissue|branching involved in mammary gland duct morphogenesis|mammary gland fat development|mammary duct terminal end bud growth|,cytokine activity|macrophage colony-stimulating factor receptor binding|protein binding|growth factor activity|protein homodimerization activity|protein homodimerization activity|,10,0,0,10,0.3,1.45,0.3,0.502,0.502,0.739,0,0,-0.6,2
ENSMUSG00000053838,NUDCD3,NudC domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0.8,0.789,10,0.2,0.514,0.1,0.5,0.5,0.739,0,0,-0.5,2
ENSMUSG00000070425,TRPC2,"transient receptor potential cation channel, subfamily C, member 2",Golgi membrane|nucleus|nuclear envelope|endoplasmic reticulum membrane|plasma membrane|microvillus|endomembrane system|membrane|integral component of membrane|dendrite membrane|,"single strand break repair|inter-male aggressive behavior|territorial aggressive behavior|transport|ion transport|calcium ion transport|positive regulation of cytosolic calcium ion concentration|acrosome reaction|female courtship behavior|regulation of gene expression|response to pheromone|mating behavior, sex discrimination|transmembrane transport|calcium ion transmembrane transport|negative regulation of male mating behavior|","damaged DNA binding|ion channel activity|calcium channel activity|protein binding|calmodulin binding|store-operated calcium channel activity|diacylglycerol binding|inositol 1,4,5 trisphosphate binding|",10,1,3.72,10,0,0,1,0.497,0.497,0.74,0,0,-0.4,2
ENSMUSG00000055980,IRS1,insulin receptor substrate 1,intracellular|nucleus|cytoplasm|cytosol|plasma membrane|plasma membrane|insulin receptor complex|caveola|ciliary basal body|intracellular membrane-bounded organelle|,positive regulation of mesenchymal cell proliferation|signal transduction|insulin receptor signaling pathway|regulation of gene expression|positive regulation of glucose metabolic process|phosphatidylinositol 3-kinase signaling|lipid catabolic process|positive regulation of cell migration|mammary gland development|response to caffeine|positive regulation of fatty acid beta-oxidation|response to insulin|cellular response to insulin stimulus|cellular response to insulin stimulus|protein localization to nucleus|protein localization to nucleus|positive regulation of phosphorylation|response to peptide hormone|protein kinase B signaling|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of glycogen biosynthetic process|positive regulation of glucose import|negative regulation of insulin receptor signaling pathway|positive regulation of insulin receptor signaling pathway|negative regulation of insulin secretion|insulin-like growth factor receptor signaling pathway|protein heterooligomerization|positive regulation of glucagon secretion|negative regulation of somatostatin secretion|positive regulation of glucose import in response to insulin stimulus|,signal transducer activity|transmembrane receptor protein tyrosine kinase adaptor activity|protein kinase C binding|insulin receptor binding|insulin-like growth factor receptor binding|protein binding|protein kinase binding|protein kinase binding|protein domain specific binding|SH2 domain binding|phosphatidylinositol 3-kinase binding|phosphatidylinositol 3-kinase binding|,10,0.1,0.116,10,0.1,0.422,0.1,0.493,0.493,0.741,0,0,-1.7,1.2
ENSMUSG00000031997,TRPC6,"transient receptor potential cation channel, subfamily C, member 6",plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|slit diaphragm|,transport|ion transport|calcium ion transport|positive regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration|positive regulation of ion transmembrane transporter activity|positive regulation of calcium ion transport|transmembrane transport|cellular response to hydrogen peroxide|calcium ion transmembrane transport|,"ion channel activity|cation channel activity|calcium channel activity|protein binding|store-operated calcium channel activity|inositol 1,4,5 trisphosphate binding|",10,0,0,10,-0.2,1.07,-0.2,0.49,-0.49,0.742,0,0,-1.4,1.3
ENSMUSG00000025499,HRAS,Harvey rat sarcoma virus oncogene,intracellular|Golgi apparatus|plasma membrane|membrane|intracellular membrane-bounded organelle|,positive regulation of protein phosphorylation|GTP catabolic process|endocytosis|apoptotic process|cell cycle arrest|mitotic cell cycle checkpoint|signal transduction|small GTPase mediated signal transduction|Ras protein signal transduction|Ras protein signal transduction|cell aging|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of gene expression|negative regulation of gene expression|positive regulation of cell migration|positive regulation of Rac GTPase activity|negative regulation of Rho GTPase activity|positive regulation of MAP kinase activity|positive regulation of MAPK cascade|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of DNA replication|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|positive regulation of Ras protein signal transduction|regulation of long-term neuronal synaptic plasticity|positive regulation of epithelial cell proliferation|protein heterooligomerization|positive regulation of ERK1 and ERK2 cascade|positive regulation of wound healing|cellular senescence|intrinsic apoptotic signaling pathway|intrinsic apoptotic signaling pathway|positive regulation of ruffle assembly|positive regulation of actin cytoskeleton reorganization|positive regulation of miRNA metabolic process|,nucleotide binding|protein binding|GTP binding|GTP binding|protein C-terminus binding|,10,-0.1,0.229,10,-0.1,0.298,-0.1,0.481,-0.481,0.744,0,0,-1.5,1.3
ENSMUSG00000035958,TDP2,tyrosyl-DNA phosphodiesterase 2,nucleus|cytoplasm|PML body|intercellular bridge|,DNA repair|double-strand break repair|cellular response to DNA damage stimulus|nucleic acid phosphodiester bond hydrolysis|,"magnesium ion binding|single-stranded DNA binding|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|photoreceptor cyclic-nucleotide phosphodiesterase activity|nuclease activity|endonuclease activity|phosphoric diester hydrolase activity|hydrolase activity|manganese ion binding|tyrosyl-RNA phosphodiesterase activity|7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity|metal ion binding|inositol phosphosphingolipid phospholipase activity|inositol phosphorylceramide phospholipase activity|mannosyl-inositol phosphorylceramide phospholipase activity|mannosyl-diinositol phosphorylceramide phospholipase activity|5'-tyrosyl-DNA phosphodiesterase activity|",10,0.1,0.00987,10,0.1,0.514,0.1,0.481,0.481,0.744,0,0,-0.9,1.9
ENSMUSG00000047492,INHBE,inhibin beta E,extracellular region|,None,hormone activity|growth factor activity|,10,-0.2,0.779,10,0,0,-0.1,0.478,-0.478,0.745,0,0,-1,2
ENSMUSG00000045322,TLR9,toll-like receptor 9,cytoplasm|lysosome|endosome|endoplasmic reticulum|plasma membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|cytoplasmic vesicle|early phagosome|,microglial cell activation|toll-like receptor signaling pathway|response to molecule of bacterial origin|immune system process|MyD88-dependent toll-like receptor signaling pathway|inflammatory response|immune response|signal transduction|I-kappaB phosphorylation|response to virus|positive regulation of autophagy|maintenance of gastrointestinal epithelium|negative regulation of NF-kappaB transcription factor activity|negative regulation of interleukin-6 production|negative regulation of interleukin-8 production|positive regulation of chemokine production|positive regulation of interferon-beta production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-18 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|negative regulation of toll-like receptor signaling pathway|positive regulation of toll-like receptor signaling pathway|toll-like receptor 9 signaling pathway|positive regulation of NF-kappaB import into nucleus|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of JUN kinase activity|positive regulation of interferon-gamma biosynthetic process|innate immune response|positive regulation of interferon-alpha biosynthetic process|positive regulation of interferon-beta biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of cytokine secretion|regulation of inflammatory response|positive regulation of inflammatory response|defense response to Gram-negative bacterium|positive regulation of NF-kappaB transcription factor activity|defense response to virus|defense response to virus|positive regulation of nitric-oxide synthase biosynthetic process|,transmembrane signaling receptor activity|interleukin-1 receptor binding|protein binding|siRNA binding|unmethylated CpG binding|,10,-0.2,0.649,10,0,0,-0.1,0.477,-0.477,0.745,0,0,-1.6,1.2
ENSMUSG00000040760,APPL1,"adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1",nucleus|endosome|cytosol|endosome membrane|vesicle membrane|membrane|NuRD complex|extracellular vesicular exosome|,cell cycle|cell proliferation|regulation of glucose import|regulation of establishment of protein localization to plasma membrane|,identical protein binding|protein kinase B binding|,10,-0.4,1.35,10,0,0,-0.2,0.471,-0.471,0.746,0,0,-2,0.6
ENSMUSG00000034394,LIF,leukemia inhibitory factor,extracellular region|extracellular space|cytoplasm|,blood vessel remodeling|transcription from RNA polymerase II promoter|immune response|embryo implantation|embryo implantation|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of neuron projection development|negative regulation of angiogenesis|stem cell maintenance|stem cell maintenance|lung development|organ regeneration|positive regulation of peptidyl-serine phosphorylation|positive regulation of peptidyl-serine phosphorylation of STAT protein|tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of MAPK cascade|regulation of cell differentiation|positive regulation of macrophage differentiation|negative regulation of meiosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|decidualization|decidualization|negative regulation of hormone secretion|lung alveolus development|muscle organ morphogenesis|neuron development|astrocyte differentiation|positive regulation of astrocyte differentiation|leukemia inhibitory factor signaling pathway|stem cell differentiation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of corticotropin secretion|retina development in camera-type eye|maternal process involved in female pregnancy|transdifferentiation|lung vasculature development|lung lobe morphogenesis|trophoblast giant cell differentiation|spongiotrophoblast differentiation|negative regulation of ERK1 and ERK2 cascade|positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|regulation of metanephric nephron tubule epithelial cell differentiation|positive regulation of protein localization to nucleus|positive regulation of histone H3-K27 acetylation|,RNA polymerase II transcription factor recruiting transcription factor activity|receptor binding|cytokine activity|cytokine activity|leukemia inhibitory factor receptor binding|growth factor activity|growth factor activity|,10,-0.6,0.375,10,-1,0.78,-0.7,0.47,-0.47,0.746,0,0,-2,0.3
ENSMUSG00000024659,ANXA1,annexin A1,cornified envelope|extracellular space|nucleus|cytoplasm|plasma membrane|cilium|cell surface|membrane|mitochondrial membrane|sarcolemma|mast cell granule|cell projection|protein complex|extracellular vesicular exosome|,DNA strand renaturation|neutrophil homeostasis|neutrophil homeostasis|ATP catabolic process|signal transduction|cell surface receptor signaling pathway|peptide cross-linking|insulin secretion|keratinocyte differentiation|positive regulation of vesicle fusion|positive regulation of prostaglandin biosynthetic process|DNA duplex unwinding|positive regulation of neutrophil apoptotic process|DNA rewinding|regulation of cell proliferation|positive regulation of apoptotic process|negative regulation of catalytic activity|alpha-beta T cell differentiation|arachidonic acid secretion|negative regulation of protein secretion|cellular response to hydrogen peroxide|prolactin secretion|cellular response to glucocorticoid stimulus|neutrophil clearance|positive regulation of G1/S transition of mitotic cell cycle|negative regulation of phospholipase A2 activity|negative regulation of interleukin-8 secretion|,"single-stranded DNA binding|single-stranded DNA binding|single-stranded RNA binding|helicase activity|phospholipase inhibitor activity|structural molecule activity|calcium ion binding|protein binding|phospholipid binding|calcium-dependent phospholipid binding|phospholipase A2 inhibitor activity|protein binding, bridging|double-stranded DNA-dependent ATPase activity|annealing helicase activity|protein homodimerization activity|calcium-dependent protein binding|",10,0.3,1.21,10,0,0,0.1,0.47,0.47,0.746,0,0,-1.1,1.7
ENSMUSG00000074934,GREM1,gremlin 1,extracellular region|extracellular space|extracellular space|cell surface|cell surface|,"cell morphogenesis|angiogenesis|branching involved in ureteric bud morphogenesis|cell migration involved in sprouting angiogenesis|positive regulation of receptor internalization|negative regulation of leukocyte chemotaxis|positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|mesenchymal to epithelial transition involved in metanephros morphogenesis|signal transduction|signal transduction|activation of transmembrane receptor protein tyrosine kinase activity|cell-cell signaling|positive regulation of cell proliferation|organ morphogenesis|proximal/distal pattern formation|regulation of epithelial to mesenchymal transition|collagen fibril organization|negative regulation of cell growth|embryonic limb morphogenesis|negative regulation of bone mineralization|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of osteoblast proliferation|positive regulation of NF-kappaB import into nucleus|endothelial cell migration|positive regulation of angiogenesis|positive regulation of angiogenesis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of bone remodeling|determination of dorsal identity|positive regulation of NF-kappaB transcription factor activity|regulation of focal adhesion assembly|positive regulation of telomerase activity|negative regulation of pathway-restricted SMAD protein phosphorylation|ureteric bud formation|positive regulation of protein tyrosine kinase activity|negative regulation of monocyte chemotaxis|negative regulation of canonical Wnt signaling pathway|positive regulation of branching involved in ureteric bud morphogenesis|negative regulation of branching involved in ureteric bud morphogenesis|negative regulation of osteoclast proliferation|positive regulation of peptidyl-tyrosine autophosphorylation|negative regulation of bone trabecula formation|negative regulation of bone mineralization involved in bone maturation|positive regulation of receptor activity|positive regulation of receptor activity|positive regulation of cardiac muscle cell differentiation|",cytokine activity|transmembrane receptor protein tyrosine kinase activator activity|vascular endothelial growth factor receptor 2 binding|heparan sulfate proteoglycan binding|receptor agonist activity|,10,0,0,10,0.4,2.58,0.4,0.466,0.466,0.747,0,0,-0.6,1.9
ENSMUSG00000000869,IL4,interleukin 4,extracellular region|extracellular space|extracellular space|external side of plasma membrane|,"microglial cell activation|positive regulation of protein phosphorylation|innate immune response in mucosa|positive regulation of defense response to virus by host|T-helper 1 cell lineage commitment|negative regulation of acute inflammatory response|negative regulation of chronic inflammatory response|immune response|cholesterol metabolic process|positive regulation of cell proliferation|regulation of proton transport|positive regulation of B cell proliferation|B cell costimulation|positive regulation of interleukin-10 production|positive regulation of interleukin-13 production|T-helper 2 cell cytokine production|positive regulation of T cell proliferation|positive regulation of activated T cell proliferation|B cell activation|positive regulation of tyrosine phosphorylation of Stat5 protein|defense response to protozoan|negative regulation of macrophage activation|negative regulation of nitric oxide biosynthetic process|T-helper 2 cell differentiation|positive regulation of chemokine biosynthetic process|positive regulation of MHC class II biosynthetic process|positive regulation of T cell differentiation|negative regulation of osteoclast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of isotype switching to IgE isotypes|positive regulation of isotype switching to IgG isotypes|regulation of inflammatory response|positive regulation of peptidyl-tyrosine phosphorylation|regulation of immune response|negative regulation of T cell activation|positive regulation of B cell activation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of mononuclear cell migration|dendritic cell differentiation|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of T-helper 17 cell differentiation|positive regulation of eosinophil chemotaxis|negative regulation of extrinsic apoptotic signaling pathway|",cytokine activity|cytokine receptor binding|interleukin-4 receptor binding|growth factor activity|,10,0.1,0.162,10,-0.2,1.13,-0.2,0.46,-0.46,0.749,0,0,-1.6,1.1
ENSMUSG00000042207,KDM5B,lysine (K)-specific demethylase 5B,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H3-K4 demethylation|histone H3-K4 demethylation|histone H3-K4 demethylation, trimethyl-H3-K4-specific|negative regulation of transcription, DNA-templated|oxidation-reduction process|","sulfonate dioxygenase activity|DNA binding|transcription corepressor activity|protein binding|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|histone demethylase activity (H3-K4 specific)|histone demethylase activity (H3-trimethyl-K4 specific)|histone demethylase activity (H3-dimethyl-K4 specific)|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.2,0.364,10,-0.3,0.206,-0.2,0.46,-0.46,0.749,0,0,-1.7,1
ENSMUSG00000032366,TPM1,"tropomyosin 1, alpha",cytoplasm|cytoskeleton|muscle thin filament tropomyosin|myofibril|filamentous actin|protein complex|,in utero embryonic development|positive regulation of heart rate by epinephrine|embryo development|muscle filament sliding|negative regulation of cell migration|ruffle organization|positive regulation of ATPase activity|wound healing|regulation of ATPase activity|positive regulation of cell adhesion|positive regulation of stress fiber assembly|actin filament capping|ventricular cardiac muscle tissue morphogenesis|cardiac muscle contraction|cardiac muscle contraction|,actin binding|structural constituent of cytoskeleton|protein homodimerization activity|protein N-terminus binding|actin filament binding|,10,-0.2,1.56,10,0,0,-0.1,0.458,-0.458,0.749,0,0,-1.1,1.8
ENSMUSG00000007655,CAV1,"caveolin 1, caveolae protein",Golgi membrane|acrosomal membrane|intracellular|intracellular|cytoplasm|mitochondrion|endosome|peroxisomal membrane|endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|lipid particle|cytosol|plasma membrane|plasma membrane|integral component of plasma membrane|caveola|caveola|caveola|focal adhesion|cilium|cell cortex|basal plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|cytoplasmic vesicle|protein complex|protein complex|membrane raft|membrane raft|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|inactivation of MAPK activity|angiogenesis|vasculogenesis|response to hypoxia|negative regulation of endothelial cell proliferation|negative regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|negative regulation of cytokine-mediated signaling pathway|regulation of the force of heart contraction|response to ischemia|regulation of the force of heart contraction by chemical signal|triglyceride metabolic process|calcium ion transport|cellular calcium ion homeostasis|cellular calcium ion homeostasis|endocytosis|regulation of smooth muscle contraction|skeletal muscle tissue development|lactation|protein localization|negative regulation of cell proliferation|response to mechanical stimulus|positive regulation of signal transduction|negative regulation of signal transduction|positive regulation of calcium ion transport into cytosol|negative regulation of muscle cell apoptotic process|positive regulation of peptidase activity|vesicle organization|regulation of fatty acid metabolic process|lipid storage|regulation of blood coagulation|negative regulation of BMP signaling pathway|negative regulation of epithelial cell differentiation|mammary gland development|positive regulation of microtubule polymerization|T cell costimulation|negative regulation of protein ubiquitination|negative regulation of protein ubiquitination|negative regulation of protein binding|maintenance of protein location in cell|response to progesterone|negative regulation of peptidyl-serine phosphorylation|positive regulation of peptidyl-serine phosphorylation|cholesterol efflux|nitric oxide homeostasis|vasoconstriction|negative regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|cholesterol homeostasis|negative regulation of MAP kinase activity|negative regulation of MAPK cascade|response to estrogen|response to estrogen|negative regulation of nitric oxide biosynthetic process|negative regulation of neuron differentiation|positive regulation of endocytosis|positive regulation of vasoconstriction|positive regulation of vasoconstriction|negative regulation of JAK-STAT cascade|negative regulation of JAK-STAT cascade|negative regulation of JAK-STAT cascade|microtubule polymerization|negative regulation of pinocytosis|positive regulation of metalloenzyme activity|negative regulation of smooth muscle cell proliferation|negative regulation of nitric-oxide synthase activity|protein oligomerization|protein homooligomerization|cytosolic calcium ion homeostasis|response to calcium ion|membrane depolarization|regulation of peptidase activity|calcium ion homeostasis|mammary gland involution|negative regulation of ERK1 and ERK2 cascade|caveola assembly|caveola assembly|cellular response to mechanical stimulus|cellular response to hyperoxia|caveolin-mediated endocytosis|negative regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|apoptotic signaling pathway|receptor internalization involved in canonical Wnt signaling pathway|negative regulation of anoikis|negative regulation of anoikis|positive regulation of extrinsic apoptotic signaling pathway|positive regulation of intrinsic apoptotic signaling pathway|negative regulation of cation channel activity|,SNARE binding|receptor binding|structural molecule activity|protein binding|peptidase activator activity|enzyme binding|kinase binding|syntaxin binding|nitric-oxide synthase binding|,10,0.1,0.227,10,-0.1,0.519,-0.1,0.456,-0.456,0.75,0,0,-1.2,1.7
ENSMUSG00000063063,CTNNA2,"catenin (cadherin associated protein), alpha 2",cytoplasm|cytoskeleton|plasma membrane|adherens junction|cell-cell adherens junction|actin cytoskeleton|membrane|basolateral plasma membrane|lamellipodium|cell junction|axon|cell projection|,cell adhesion|multicellular organismal development|axonogenesis|radial glia guided migration of Purkinje cell|cell differentiation|dendrite morphogenesis|brain morphogenesis|regulation of synapse structural plasticity|prepulse inhibition|,structural molecule activity|cadherin binding|,10,-0.2,0.357,10,-0.1,0.152,-0.1,0.455,-0.455,0.75,0,0,-1.7,1.1
ENSMUSG00000052221,PPP1R36,"protein phosphatase 1, regulatory subunit 36",cellular_component|,negative regulation of phosphatase activity|,protein phosphatase inhibitor activity|phosphatase binding|,10,-0.4,1.59,10,0.5,0.855,-0.2,0.455,-0.455,0.75,0,0,-1.7,1.3
ENSMUSG00000004651,TYR,tyrosinase,cytoplasm|membrane|integral component of membrane|melanosome|perinuclear region of cytoplasm|,metabolic process|cell proliferation|melanin biosynthetic process|pigmentation|pigmentation|thymus development|oxidation-reduction process|oxidation-reduction process|,monooxygenase activity|monophenol monooxygenase activity|monophenol monooxygenase activity|copper ion binding|protein binding|oxidoreductase activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,9,-0.2,1.46,9,0.4,0.415,-0.1,0.455,-0.455,0.75,0,0,-1.4,1.5
ENSMUSG00000095754,SPIN2F,"spindlin family, member 2F",cellular_component|,biological_process|,molecular_function|,10,0.1,0.476,9,0.1,0.0115,0.1,0.447,0.447,0.752,0,0,-1.2,1.7
ENSMUSG00000057329,BCL2,B cell leukemia/lymphoma 2,intracellular|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|cytosol|membrane|membrane|integral component of membrane|nuclear membrane|nuclear membrane|mitochondrial membrane|myelin sheath|pore complex|,"protein polyubiquitination|cell morphogenesis|response to acid|ossification|ovarian follicle development|metanephros development|ureteric bud development|branching involved in ureteric bud morphogenesis|branching involved in ureteric bud morphogenesis|behavioral fear response|leukocyte homeostasis|B cell homeostasis|kidney development|kidney development|release of cytochrome c from mitochondria|regulation of cell-matrix adhesion|lymphocyte homeostasis|lymphocyte homeostasis|lymphoid progenitor cell differentiation|B cell lineage commitment|T cell lineage commitment|immune system development|response to ischemia|renal system process|protein dephosphorylation|melanin metabolic process|regulation of nitrogen utilization|cellular calcium ion homeostasis|apoptotic process|apoptotic process|cellular response to DNA damage stimulus|response to oxidative stress|actin filament organization|axonogenesis|cell aging|cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|male gonad development|extrinsic apoptotic signaling pathway via death domain receptors|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to oxidative stress|apoptotic mitochondrial changes|response to toxic substance|response to toxic substance|post-embryonic development|post-embryonic development|organ morphogenesis|response to iron ion|response to UV-B|response to gamma radiation|regulation of gene expression|negative regulation of calcium ion transport into cytosol|regulation of glycoprotein biosynthetic process|mesenchymal cell development|positive regulation of neuron maturation|positive regulation of smooth muscle cell migration|cell growth|single organismal cell-cell adhesion|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|cochlear nucleus development|gland morphogenesis|regulation of transmembrane transporter activity|hemopoiesis|B cell differentiation|T cell differentiation|negative regulation of ossification|positive regulation of cell growth|negative regulation of cell growth|melanocyte differentiation|melanocyte differentiation|negative regulation of cell migration|positive regulation of B cell proliferation|hair follicle morphogenesis|axon regeneration|regulation of protein stability|endoplasmic reticulum calcium ion homeostasis|glomerulus development|negative regulation of cellular pH reduction|regulation of protein localization|negative regulation of myeloid cell apoptotic process|T cell differentiation in thymus|positive regulation of peptidyl-serine phosphorylation|negative regulation of osteoblast proliferation|response to cytokine|response to cytokine|response to nicotine|organ growth|growth|positive regulation of multicellular organism growth|B cell proliferation|cellular response to glucose starvation|response to drug|response to drug|response to hydrogen peroxide|regulation of apoptotic process|T cell homeostasis|T cell homeostasis|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of programmed cell death|positive regulation of catalytic activity|CD8-positive, alpha-beta T cell lineage commitment|pigmentation|regulation of protein homodimerization activity|regulation of protein heterodimerization activity|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|ear development|ear development|regulation of viral genome replication|positive regulation of melanocyte differentiation|negative regulation of mitotic cell cycle|negative regulation of retinal cell programmed cell death|regulation of mitochondrial membrane permeability|focal adhesion assembly|developmental pigmentation|developmental pigmentation|regulation of developmental pigmentation|positive regulation of developmental pigmentation|positive regulation of developmental pigmentation|spleen development|spleen development|thymus development|thymus development|response to steroid hormone|digestive tract morphogenesis|developmental growth|oocyte development|positive regulation of skeletal muscle fiber development|pigment granule organization|homeostasis of number of cells within a tissue|regulation of catalytic activity|B cell receptor signaling pathway|response to glucocorticoid|response to glucocorticoid|neuron apoptotic process|neuron apoptotic process|defense response to virus|regulation of cell cycle|regulation of mitochondrial membrane potential|regulation of calcium ion transport|transmembrane transport|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|cellular response to organic substance|cellular response to hypoxia|reactive oxygen species metabolic process|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of G1/S transition of mitotic cell cycle|negative regulation of G1/S transition of mitotic cell cycle|negative regulation of anoikis|negative regulation of apoptotic signaling pathway|negative regulation of apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway|",protease binding|protein binding|transcription factor binding|channel activity|channel inhibitor activity|protein phosphatase binding|ubiquitin protein ligase binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|BH domain binding|BH3 domain binding|protein phosphatase 2A binding|,10,0,0,10,0.3,1.31,0.2,0.446,0.446,0.753,0,0,-1,1.7
ENSMUSG00000025880,SMAD7,SMAD family member 7,intracellular|nucleus|nucleus|transcription factor complex|cytoplasm|plasma membrane|cell-cell adherens junction|catenin complex|protein complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transforming growth factor beta receptor signaling pathway|negative regulation of peptidyl-threonine phosphorylation|negative regulation of peptidyl-threonine phosphorylation|negative regulation of transcription by competitive promoter binding|regulation of transforming growth factor beta receptor signaling pathway|regulation of transforming growth factor beta receptor signaling pathway|positive regulation of cell-cell adhesion|positive regulation of cell-cell adhesion|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of protein ubiquitination|positive regulation of protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|regulation of activin receptor signaling pathway|negative regulation of peptidyl-serine phosphorylation|negative regulation of peptidyl-serine phosphorylation|adherens junction assembly|cellular protein complex localization|intracellular signal transduction|negative regulation of sequence-specific DNA binding transcription factor activity|artery morphogenesis|protein stabilization|negative regulation of ubiquitin-protein transferase activity|ventricular cardiac muscle tissue morphogenesis|regulation of cardiac muscle contraction|regulation of ventricular cardiac muscle cell membrane depolarization|pathway-restricted SMAD protein phosphorylation|negative regulation of pathway-restricted SMAD protein phosphorylation|ventricular septum morphogenesis|cellular response to transforming growth factor beta stimulus|cellular response to transforming growth factor beta stimulus|","DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|collagen binding|beta-catenin binding|transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity|ubiquitin protein ligase binding|type I transforming growth factor beta receptor binding|transcription regulatory region DNA binding|metal ion binding|activin binding|I-SMAD binding|",10,0.2,0.882,10,0,0,0.1,0.442,0.442,0.754,0,0,-1.5,1.4
ENSMUSG00000034205,LOXL2,lysyl oxidase-like 2,basement membrane|extracellular space|nucleus|,"epithelial to mesenchymal transition|endothelial cell proliferation|sprouting angiogenesis|cellular protein modification process|histone modification|protein deamination|collagen fibril organization|endothelial cell migration|negative regulation of transcription, DNA-templated|response to copper ion|oxidation-reduction process|",chromatin binding|transcription corepressor activity|protein-lysine 6-oxidase activity|methylated histone binding|oligosaccharide binding|,10,-0.1,0.528,10,0.2,1.05,0.1,0.441,0.441,0.754,0,0,-1.2,1.6
ENSMUSG00000008136,FHL2,four and a half LIM domains 2,nucleus|nucleus|cytoplasm|focal adhesion|actin cytoskeleton|Z disc|M band|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|response to hormone|negative regulation of apoptotic process|negative regulation of transcription, DNA-templated|",protein binding|transcription factor binding|zinc ion binding|identical protein binding|metal ion binding|,10,-0.1,0.357,10,-0.4,0.334,-0.1,0.44,-0.44,0.754,0,0,-1.7,1.1
ENSMUSG00000039062,ANPEP,alanyl (membrane) aminopeptidase,extracellular space|lysosomal membrane|endoplasmic reticulum-Golgi intermediate compartment|external side of plasma membrane|vesicle membrane|membrane|integral component of membrane|vesicle lumen|extracellular vesicular exosome|,angiogenesis|proteolysis|cellular aromatic compound metabolic process|multicellular organismal development|cell differentiation|negative regulation of renal sodium excretion|,aminopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|peptide binding|metal ion binding|,10,0.2,0.805,10,-0.2,0.992,-0.1,0.439,-0.439,0.754,0,0,-1.3,1.5
ENSMUSG00000062181,CES3B,carboxylesterase 3B,endoplasmic reticulum|extracellular vesicular exosome|,biological_process|,hydrolase activity|carboxylic ester hydrolase activity|,10,0.2,0.564,10,0.1,0.128,0.1,0.431,0.431,0.757,0,0,-1,1.8
ENSMUSG00000026193,FN1,fibronectin 1,extracellular region|fibrinogen complex|proteinaceous extracellular matrix|proteinaceous extracellular matrix|basement membrane|basement membrane|basal lamina|extracellular space|endoplasmic reticulum-Golgi intermediate compartment|apical plasma membrane|extracellular matrix|extracellular matrix|extracellular matrix|extracellular vesicular exosome|blood microparticle|,angiogenesis|cell activation|acute-phase response|cell-substrate junction assembly|cell adhesion|cell-matrix adhesion|cell-matrix adhesion|calcium-independent cell-matrix adhesion|glial cell migration|regulation of cell shape|positive regulation of peptidase activity|peptide cross-linking|extracellular matrix organization|positive regulation of cell migration|substrate adhesion-dependent cell spreading|wound healing|negative regulation of apoptotic process|positive regulation of axon extension|positive regulation of chemotaxis|cellular response to mercury ion|cellular response to interleukin-1|,protease binding|integrin binding|protein binding|heparin binding|peptidase activator activity|mercury ion binding|,10,0,0,10,-0.1,0.688,-0.1,0.427,-0.427,0.758,0,0,-1.7,1.2
ENSMUSG00000069053,UBA1Y,"ubiquitin-activating enzyme, Chr Y",nucleus|cytosol|,cellular protein modification process|protein ubiquitination|modification-dependent protein catabolic process|,nucleotide binding|catalytic activity|ubiquitin activating enzyme activity|ubiquitin-protein transferase activity|ATP binding|small protein activating enzyme activity|ligase activity|,10,-0.1,0.378,10,0.6,1.01,-0.1,0.424,-0.424,0.759,0,0,-1.6,1.5
ENSMUSG00000021033,GSTZ1,glutathione transferase zeta 1 (maleylacetoacetate isomerase),cytoplasm|mitochondrion|,L-phenylalanine catabolic process|tyrosine catabolic process|glutathione metabolic process|metabolic process|aromatic amino acid family metabolic process|,catalytic activity|glutathione transferase activity|glutathione transferase activity|maleylacetoacetate isomerase activity|maleylacetoacetate isomerase activity|transferase activity|isomerase activity|protein homodimerization activity|,10,0,0,10,-0.2,0.665,-0.1,0.423,-0.423,0.759,0,0,-2,0.7
ENSMUSG00000060177,KLK1B22,kallikrein 1-related peptidase b22,nucleus|,proteolysis|zymogen activation|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.0969,10,-0.2,0.929,-0.2,0.422,-0.422,0.759,0,0,-1.9,0.8
ENSMUSG00000029723,TSC22D4,"TSC22 domain family, member 4",nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|response to osmotic stress|",sequence-specific DNA binding transcription factor activity|protein binding|,10,0.1,0.0871,10,0.1,0.374,0.1,0.422,0.422,0.759,0,0,-1.1,1.7
ENSMUSG00000062074,WISP3,WNT1 inducible signaling pathway protein 3,cellular_component|extracellular region|,regulation of cell growth|negative regulation of cell proliferation|negative regulation of angiogenesis|,molecular_function|insulin-like growth factor binding|growth factor activity|,10,-0.5,0.88,10,0,0,-0.1,0.421,-0.421,0.759,0,0,-2,0.7
ENSMUSG00000029378,AREG,amphiregulin,extracellular space|intracellular|nucleus|cytoplasm|cell surface|membrane|integral component of membrane|,epidermal growth factor receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cell proliferation|glial cell proliferation|neuron projection development|response to estradiol|positive regulation of phosphorylation|negative regulation of osteoblast differentiation|positive regulation of DNA replication|response to glucocorticoid|dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis|mammary gland branching involved in thelarche|mammary gland alveolus development|epithelial cell proliferation involved in mammary gland duct elongation|,cytokine activity|epidermal growth factor receptor binding|growth factor activity|,10,-0.1,0.494,10,0,0,-0.1,0.416,-0.416,0.76,0,0,-1.7,1.1
ENSMUSG00000031592,PCM1,pericentriolar material 1,pericentriolar material|cell|cytoplasm|cytoplasm|centrosome|centrosome|centrosome|cytoskeleton|cilium|membrane|nuclear membrane|centriolar satellite|centriolar satellite|ciliary basal body|cell projection|protein complex|,interkinetic nuclear migration|cell projection organization|cytoplasmic microtubule organization|microtubule anchoring|microtubule anchoring at centrosome|intraciliary transport involved in cilium morphogenesis|cilium assembly|negative regulation of neurogenesis|centrosome organization|protein localization to centrosome|positive regulation of intracellular protein transport|neuronal stem cell maintenance|,protein binding|,10,-0.2,0.31,10,-0.2,0.144,-0.2,0.414,-0.414,0.761,0,0,-1.6,1.1
ENSMUSG00000068205,MACROD2,MACRO domain containing 2,nucleus|,cellular response to DNA damage stimulus|purine nucleoside metabolic process|protein de-ADP-ribosylation|,"purine-specific mismatch base pair DNA N-glycosylase activity|histone deacetylase activity|uracil DNA N-glycosylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|single-strand selective uracil DNA N-glycosylase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|DNA N-glycosylase activity|deacetylase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|DNA-3-methylbase glycosylase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0,0,10,0.3,1.38,0.2,0.413,0.413,0.761,0,0,-0.8,1.8
ENSMUSG00000030790,ADM,adrenomedullin,extracellular region|extracellular space|cytoplasm|,vasculogenesis|neural tube closure|regulation of the force of heart contraction|G-protein coupled receptor internalization|cAMP biosynthetic process|positive regulation of cytosolic calcium ion concentration|heart development|androgen metabolic process|positive regulation of cell proliferation|negative regulation of cell proliferation|response to wounding|positive regulation of heart rate|positive regulation of cAMP biosynthetic process|neuron projection regeneration|receptor internalization|response to lipopolysaccharide|positive regulation of apoptotic process|negative regulation of vascular permeability|positive regulation of angiogenesis|negative regulation of vasoconstriction|positive regulation of vasodilation|hormone secretion|developmental growth|calcium ion homeostasis|branching involved in labyrinthine layer morphogenesis|spongiotrophoblast layer development|vascular smooth muscle cell development|positive regulation of vasculogenesis|,hormone activity|adrenomedullin receptor binding|,10,-0.6,1.24,10,0.2,0.278,-0.3,0.411,-0.411,0.761,0,0,-1.9,0.7
ENSMUSG00000005640,INSRR,insulin receptor-related receptor,integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,protein phosphorylation|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|phosphorylation|peptidyl-tyrosine phosphorylation|male sex determination|actin cytoskeleton reorganization|protein autophosphorylation|protein autophosphorylation|cellular response to alkalinity|cellular response to alkalinity|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphatidylinositol 3-kinase binding|insulin receptor substrate binding|",10,0,0,10,-0.2,0.849,-0.1,0.403,-0.403,0.763,0,0,-1.7,1.1
ENSMUSG00000019326,AOC3,"amine oxidase, copper containing 3",extracellular space|cytoplasm|plasma membrane|microvillus|cell surface|membrane|integral component of membrane|intracellular membrane-bounded organelle|,leukocyte migration involved in inflammatory response|positive regulation of acute inflammatory response|positive regulation of leukocyte migration|cation transport|cell adhesion|regulation of blood pressure|amine metabolic process|positive regulation of glucose transport|ion transmembrane transport|response to immobilization stress|eating behavior|response to antibiotic|oxidation-reduction process|,cation channel activity|copper ion binding|calcium ion binding|primary amine oxidase activity|oxidoreductase activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|quinone binding|tryptamine:oxygen oxidoreductase (deaminating) activity|aminoacetone:oxygen oxidoreductase(deaminating) activity|aliphatic-amine oxidase activity|phenethylamine:oxygen oxidoreductase (deaminating) activity|,10,0,0,10,0.1,1.07,0.1,0.398,0.398,0.765,0,0,-1.1,1.8
ENSMUSG00000024029,TFF3,"trefoil factor 3, intestinal",extracellular region|proteinaceous extracellular matrix|secretory granule|extracellular vesicular exosome|,None,None,10,0.1,0.396,10,0.1,0.0392,0.1,0.398,0.398,0.765,0,0,-0.9,1.8
ENSMUSG00000019768,ESR1,estrogen receptor 1 (alpha),nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|Golgi apparatus|plasma membrane|membrane|T-tubule|neuron projection|terminal bouton|perikaryon|protein complex|perinuclear region of cytoplasm|,"antral ovarian follicle growth|epithelial cell development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|androgen metabolic process|male gonad development|negative regulation of gene expression|positive regulation of phospholipase C activity|cell growth|intracellular steroid hormone receptor signaling pathway|intracellular estrogen receptor signaling pathway|intracellular receptor signaling pathway|response to estradiol|regulation of apoptotic process|negative regulation of I-kappaB kinase/NF-kappaB signaling|steroid hormone mediated signaling pathway|negative regulation of sequence-specific DNA binding transcription factor activity|regulation of neuron apoptotic process|response to estrogen|positive regulation of nitric oxide biosynthetic process|positive regulation of epidermal growth factor receptor signaling pathway|negative regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of glucose import|positive regulation of fibroblast proliferation|positive regulation of retinoic acid receptor signaling pathway|negative regulation of smooth muscle cell proliferation|positive regulation of nitric-oxide synthase activity|positive regulation of sequence-specific DNA binding transcription factor activity|Sertoli cell proliferation|uterus development|vagina development|prostate epithelial cord elongation|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis|regulation of branching involved in prostate gland morphogenesis|mammary gland branching involved in pregnancy|mammary gland alveolus development|epithelial cell proliferation involved in mammary gland duct elongation|positive regulation of ERK1 and ERK2 cascade|cellular response to estrogen stimulus|cellular response to estradiol stimulus|negative regulation of triglyceride metabolic process|negative regulation of neuron death|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|steroid binding|protein binding|beta-catenin binding|transcription factor binding|zinc ion binding|lipid binding|enzyme binding|estrogen receptor activity|type 1 metabotropic glutamate receptor binding|protein complex binding|estrogen response element binding|estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|hormone binding|identical protein binding|sequence-specific DNA binding|metal ion binding|,10,0.1,0.033,10,0.1,0.4,0.1,0.397,0.397,0.765,0,0,-1,1.8
ENSMUSG00000022892,APP,amyloid beta (A4) precursor protein,extracellular space|intracellular|cell|nuclear envelope lumen|cytoplasm|cytoplasm|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|plasma membrane|plasma membrane|coated pit|cell-cell junction|cell surface|membrane|membrane|integral component of membrane|ER to Golgi transport vesicle|axon|axon|cytoplasmic vesicle|neuromuscular junction|ciliary rootlet|neuron projection|neuron projection|intracellular membrane-bounded organelle|receptor complex|membrane raft|apical part of cell|perinuclear region of cytoplasm|perinuclear region of cytoplasm|spindle midzone|extracellular vesicular exosome|,suckling behavior|mRNA polyadenylation|regulation of translation|protein phosphorylation|cellular copper ion homeostasis|cellular copper ion homeostasis|endocytosis|apoptotic process|response to oxidative stress|cell adhesion|regulation of epidermal growth factor-activated receptor activity|Notch signaling pathway|nervous system development|axonogenesis|mating behavior|locomotory behavior|axon cargo transport|axon cargo transport|cholesterol metabolic process|cholesterol metabolic process|adult locomotory behavior|visual learning|negative regulation of peptidase activity|regulation of gene expression|negative regulation of endopeptidase activity|positive regulation of peptidase activity|positive regulation of G2/M transition of mitotic cell cycle|axon midline choice point recognition|neuron remodeling|dendrite development|dendrite development|extracellular matrix organization|forebrain development|neuron projection development|ionotropic glutamate receptor signaling pathway|regulation of multicellular organism growth|regulation of protein binding|regulation of protein binding|negative regulation of neuron differentiation|negative regulation of neuron differentiation|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|collateral sprouting in absence of injury|regulation of synapse structure and activity|neuromuscular process controlling balance|synaptic growth at neuromuscular junction|protein homooligomerization|neuron apoptotic process|neuron apoptotic process|smooth endoplasmic reticulum calcium ion homeostasis|,DNA binding|serine-type endopeptidase inhibitor activity|receptor binding|protein binding|heparin binding|peptidase activator activity|enzyme binding|peptidase inhibitor activity|acetylcholine receptor binding|identical protein binding|metal ion binding|transition metal ion binding|PTB domain binding|growth factor receptor binding|,10,0,0,10,-0.2,0.596,-0.1,0.396,-0.396,0.765,0,0,-1.7,1.2
ENSMUSG00000062908,ACADM,"acyl-Coenzyme A dehydrogenase, medium chain",nucleus|mitochondrion|mitochondrion|mitochondrial matrix|axon|mitochondrial membrane|extracellular vesicular exosome|,"liver development|glycogen biosynthetic process|organic acid metabolic process|regulation of gluconeogenesis|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|heart development|metabolic process|response to cold|carnitine metabolic process|post-embryonic development|carnitine metabolic process, CoA-linked|carnitine metabolic process, CoA-linked|fatty acid beta-oxidation using acyl-CoA dehydrogenase|fatty acid beta-oxidation using acyl-CoA dehydrogenase|response to starvation|carnitine biosynthetic process|protein homotetramerization|medium-chain fatty acid metabolic process|medium-chain fatty acid metabolic process|medium-chain fatty acid catabolic process|cardiac muscle cell differentiation|oxidation-reduction process|","fatty-acyl-CoA binding|acyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|isomerase activity|identical protein binding|flavin adenine dinucleotide binding|medium-chain-acyl-CoA dehydrogenase activity|medium-chain-acyl-CoA dehydrogenase activity|",10,0,0,10,-0.9,1.94,-0.4,0.393,-0.393,0.766,0,0,-2,1.1
ENSMUSG00000020950,FOXG1,forkhead box G1,nucleus|,"positive regulation of neuroblast proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|regulation of mitotic cell cycle|dorsal/ventral pattern formation|regulation of gene expression|axon midline choice point recognition|pyramidal neuron migration|central nervous system neuron development|cerebral cortex development|neurogenesis|forebrain development|inner ear morphogenesis|inner ear morphogenesis|negative regulation of neuron differentiation|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|neuron fate determination|cell morphogenesis involved in neuron differentiation|regulation of cell cycle|regulation of neural precursor cell proliferation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,1,3.09,0.1,0.386,0.386,0.768,0,0,-0.4,2
ENSMUSG00000020326,CCNG1,cyclin G1,nucleus|dendrite|neuronal cell body|perinuclear region of cytoplasm|,syncytium formation|cell cycle|mitotic nuclear division|mitotic G2 DNA damage checkpoint|negative regulation of apoptotic process|cell division|regulation of cell cycle|,protein domain specific binding|,10,0,0,10,0.3,1.03,0.2,0.386,0.386,0.768,0,0,-2,1
ENSMUSG00000045691,THTPA,thiamine triphosphatase,cytoplasm|,thiamine metabolic process|dephosphorylation|thiamine diphosphate metabolic process|,magnesium ion binding|hydrolase activity|metal ion binding|thiamin-triphosphatase activity|thiamin-triphosphatase activity|,10,-0.1,0.0392,10,-0.7,1.09,-0.1,0.382,-0.382,0.769,0,0,-2,0.7
ENSMUSG00000003346,ABHD17A,abhydrolase domain containing 17A,extracellular region|membrane|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.3,1.3,10,0.1,0.0406,-0.1,0.378,-0.378,0.77,0,0,-1.3,1.6
ENSMUSG00000011256,ADAM19,a disintegrin and metallopeptidase domain 19 (meltrin beta),membrane|integral component of membrane|,proteolysis|membrane protein ectodomain proteolysis|integrin-mediated signaling pathway|heart development|,metalloendopeptidase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|SH3 domain binding|metal ion binding|,10,0.1,0.476,10,0,0,0.1,0.374,0.374,0.771,0,0,-1.1,1.8
ENSMUSG00000066640,FBXL18,F-box and leucine-rich repeat protein 18,cellular_component|,biological_process|,molecular_function|,10,0.1,0.22,10,0.1,0.189,0.1,0.373,0.373,0.771,0,0,-1.5,1.5
ENSMUSG00000002459,RGS20,regulator of G-protein signaling 20,nucleus|cytoplasm|Golgi apparatus|plasma membrane|membrane|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|GTPase activator activity|,10,-0.1,0.0781,10,-0.1,0.328,-0.1,0.372,-0.372,0.771,0,0,-1.6,1.2
ENSMUSG00000022129,DCT,dopachrome tautomerase,cytoplasm|cytosol|membrane|integral component of membrane|melanosome|,positive regulation of neuroblast proliferation|melanin biosynthetic process from tyrosine|metabolic process|ventricular zone neuroblast division|melanin biosynthetic process|pigmentation|developmental pigmentation|cell development|,dopachrome isomerase activity|dopachrome isomerase activity|oxidoreductase activity|isomerase activity|metal ion binding|,10,0,0,10,0.3,1.01,0.1,0.369,0.369,0.772,0,0,-0.9,1.8
ENSMUSG00000068129,CST7,cystatin F (leukocystatin),extracellular region|,negative regulation of peptidase activity|,cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0.2,1.47,0.1,0.368,0.368,0.772,0,0,-1.2,1.6
ENSMUSG00000031196,F8,coagulation factor VIII,extracellular region|extracellular space|,"proteolysis|acute-phase response|cell adhesion|blood coagulation|blood coagulation, intrinsic pathway|hemostasis|platelet activation|oxidation-reduction process|",serine-type endopeptidase activity|copper ion binding|oxidoreductase activity|metal ion binding|,10,-0.3,0.575,10,-0.1,0.00379,-0.2,0.366,-0.366,0.773,0,0,-1.7,1
ENSMUSG00000026641,USF1,upstream transcription factor 1,nucleus|transcription factor complex|transcription factor complex|,"positive regulation of transcription from RNA polymerase II promoter by glucose|positive regulation of transcription from RNA polymerase II promoter by glucose|response to hypoxia|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to UV|late viral transcription|cellular response to insulin stimulus|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|lipid homeostasis|",DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|enzyme binding|protein kinase binding|protein homodimerization activity|histone deacetylase binding|bHLH transcription factor binding|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|,10,-0.4,0.713,10,0.1,0.529,0.1,0.365,0.365,0.773,0,0,-1.8,1
ENSMUSG00000003227,EDAR,ectodysplasin-A receptor,plasma membrane|membrane|integral component of membrane|apical part of cell|,hair follicle development|hair follicle development|apoptotic process|signal transduction|multicellular organismal development|cell differentiation|positive regulation of NF-kappaB import into nucleus|odontogenesis of dentin-containing tooth|pigmentation|salivary gland cavitation|,receptor activity|,10,0.1,0.142,10,0.1,0.258,0.1,0.365,0.365,0.773,0,0,-1.3,1.6
ENSMUSG00000039828,WDR70,WD repeat domain 70,cellular_component|,biological_process|,enzyme binding|,10,0,0,10,0.2,1.08,0.1,0.365,0.365,0.773,0,0,-0.9,1.8
ENSMUSG00000053519,KCNIP1,Kv channel-interacting protein 1,plasma membrane|membrane|dendrite|potassium channel complex|neuronal cell body|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|positive regulation of action potential|potassium ion transmembrane transport|,voltage-gated ion channel activity|potassium channel activity|calcium ion binding|potassium channel regulator activity|ion channel binding|metal ion binding|protein heterodimerization activity|protein N-terminus binding|,10,0,0,10,0.1,0.458,0.1,0.364,0.364,0.773,0,0,-1.2,1.6
ENSMUSG00000056947,MAB21L1,mab-21-like 1 (C. elegans),nucleus|,multicellular organismal development|positive regulation of cell proliferation|camera-type eye development|,None,10,-0.2,0.637,10,0.2,0.827,0.1,0.363,0.363,0.774,0,0,-1.3,1.5
ENSMUSG00000047146,TET1,tet methylcytosine dioxygenase 1,nucleus|,"inner cell mass cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein O-linked glycosylation|chromatin modification|stem cell maintenance|regulation of DNA methylation|positive regulation of transcription from RNA polymerase II promoter|oxidation-reduction process|DNA demethylation|DNA demethylation|DNA demethylation|negative regulation of methylation-dependent chromatin silencing|",DNA binding|iron ion binding|protein binding|zinc ion binding|oxidoreductase activity|structure-specific DNA binding|metal ion binding|dioxygenase activity|methylcytosine dioxygenase activity|methylcytosine dioxygenase activity|,10,0,0,10,0.3,1,0.2,0.36,0.36,0.774,0,0,-1.2,1.5
ENSMUSG00000071322,TCP10A,t-complex protein 10a,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,1.97,0.3,0.359,0.359,0.775,0,0,-0.6,1.9
ENSMUSG00000021488,NSD1,nuclear receptor-binding SET-domain protein 1,nucleus|nucleus|chromosome|histone methyltransferase complex|,"negative regulation of transcription from RNA polymerase II promoter|gastrulation with mouth forming second|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|histone H3-K36 methylation|histone H3-K36 methylation|chromatin modification|histone methylation|peptidyl-lysine methylation|methylation|histone H4-K20 methylation|positive regulation of transcription, DNA-templated|",chromatin binding|transcription cofactor activity|transcription cofactor activity|transcription corepressor activity|protein binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|estrogen receptor binding|histone methyltransferase activity|histone methyltransferase activity (H4-K20 specific)|retinoic acid receptor binding|metal ion binding|retinoid X receptor binding|thyroid hormone receptor binding|histone methyltransferase activity (H3-K36 specific)|histone methyltransferase activity (H3-K36 specific)|androgen receptor binding|,10,0.2,1.3,10,-0.2,0.547,0.1,0.357,0.357,0.775,0,0,-1.4,1.3
ENSMUSG00000031310,ZMYM3,"zinc finger, MYM-type 3",nucleus|,cytoskeleton organization|regulation of cell morphogenesis|,zinc ion binding|metal ion binding|,10,-0.2,0.539,10,-0.1,0.0207,-0.1,0.353,-0.353,0.776,0,0,-1.6,1.2
ENSMUSG00000020463,SMEK2,"SMEK homolog 2, suppressor of mek1 (Dictyostelium)",nucleus|cytoplasm|cytoskeleton|protein phosphatase 4 complex|,protein dephosphorylation|regulation of lipid metabolic process|positive regulation of gluconeogenesis|,protein binding|,10,-0.7,3.2,10,0.2,0.815,0.1,0.353,0.353,0.776,0,0,-2,0.9
ENSMUSG00000032369,PLSCR1,phospholipid scramblase 1,nucleus|nucleus|nucleolus|Golgi apparatus|cytosol|cytosol|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|extracellular matrix|membrane raft|extracellular vesicular exosome|,transcription from RNA polymerase II promoter|phosphatidylserine biosynthetic process|apoptotic process|immune response|positive regulation of gene expression|phospholipid transport|phospholipid scrambling|phospholipid scrambling|myeloid cell differentiation|negative regulation of protein binding|regulation of mast cell activation|response to interferon-alpha|response to interferon-beta|positive regulation of apoptotic process|negative regulation of viral genome replication|negative regulation of viral genome replication|positive regulation of innate immune response|positive regulation of innate immune response|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|defense response to virus|regulation of Fc receptor mediated stimulatory signaling pathway|phosphatidylserine exposure on apoptotic cell surface|intrinsic apoptotic signaling pathway|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity|,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|epidermal growth factor receptor binding|calcium ion binding|SH3 domain binding|phospholipid scramblase activity|enzyme binding|CD4 receptor binding|,10,0.7,2.99,10,-0.1,0.553,0.1,0.353,0.353,0.776,0,0,-0.6,2
ENSMUSG00000041846,SMEK1,"SMEK homolog 1, suppressor of mek1 (Dictyostelium)",nucleus|cytoplasm|cytoskeleton|protein phosphatase 4 complex|,protein dephosphorylation|positive regulation of gluconeogenesis|,protein binding|,10,0.1,0.076,10,0.1,0.309,0.1,0.352,0.352,0.776,0,0,-1,1.8
ENSMUSG00000039542,NCAM1,neural cell adhesion molecule 1,cytoplasm|plasma membrane|cell-cell junction|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|axon|growth cone|anchored component of membrane|neuronal cell body|neuronal cell body|extracellular vesicular exosome|,regulation of exocyst assembly|cell adhesion|cell surface receptor signaling pathway|aging|learning or memory|response to lead ion|response to fluoxetine|thalamus development|neuron projection development|multicellular organismal response to stress|homotypic cell-cell adhesion|response to cocaine|neuron development|positive regulation of calcium-mediated signaling|regulation of sensory perception of pain|positive regulation of cardiac muscle cell proliferation|negative regulation of cell death|,protein binding|heparin binding|phosphatase binding|LRR domain binding|identical protein binding|,10,0,0,10,0.1,0.484,0.1,0.35,0.35,0.777,0,0,-1.3,1.6
ENSMUSG00000008813,TPPP2,tubulin polymerization-promoting protein family member 2,cellular_component|cytoplasm|,biological_process|,molecular_function|calcium ion binding|,10,-0.1,0.306,10,-0.1,0.0711,-0.1,0.345,-0.345,0.778,0,0,-1.6,1.2
ENSMUSG00000013483,CARD14,"caspase recruitment domain family, member 14",cytoplasm|,positive regulation of protein phosphorylation|apoptotic process|tumor necrosis factor-mediated signaling pathway|regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of NF-kappaB transcription factor activity|,CARD domain binding|,10,0.2,1.42,10,-0.2,0.341,0.2,0.345,0.345,0.778,0,0,-1.1,1.7
ENSMUSG00000072214,5-Sep,septin 5,stress fiber|cytoplasm|cytoskeleton|plasma membrane|cell cortex|synaptic vesicle|synaptic vesicle|septin complex|cleavage furrow|terminal bouton|axon terminus|synapse|,cell cycle|regulation of exocytosis|positive regulation of exocytosis|cell division|,nucleotide binding|protein binding|GTP binding|GDP binding|syntaxin binding|phosphatidylinositol binding|protein homodimerization activity|,10,0.3,1.13,10,0,0,0.1,0.343,0.343,0.779,0,0,-1,1.8
ENSMUSG00000006262,MOB1B,MOB kinase activator 1B,nucleus|cytoplasm|extracellular vesicular exosome|,phosphorylation|hippo signaling|positive regulation of phosphorylation|positive regulation of catalytic activity|protein autophosphorylation|,kinase activity|transferase activity|kinase activator activity|kinase binding|metal ion binding|,10,0.1,0.22,10,0.1,0.151,0.1,0.338,0.338,0.78,0,0,-1.8,1
ENSMUSG00000024868,DKK1,dickkopf homolog 1 (Xenopus laevis),extracellular region|extracellular space|plasma membrane|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis involved in differentiation|endoderm formation|mesoderm formation|hair follicle development|regulation of receptor internalization|multicellular organismal development|endoderm development|Wnt signaling pathway|regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|embryonic limb morphogenesis|negative regulation of BMP signaling pathway|forebrain development|negative regulation of protein complex assembly|response to retinoic acid|negative regulation of peptidyl-serine phosphorylation|negative regulation of mesodermal cell fate specification|regulation of endodermal cell fate specification|negative regulation of skeletal muscle tissue development|head morphogenesis|face morphogenesis|negative regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|Wnt signaling pathway involved in somitogenesis|extracellular negative regulation of signal transduction|negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of receptor activity|negative regulation of cardiac muscle cell differentiation|,protein binding|receptor antagonist activity|low-density lipoprotein particle receptor binding|,10,0.1,0.155,10,0.1,0.21,0.1,0.333,0.333,0.781,0,0,-1.2,1.7
ENSMUSG00000040229,GPR34,G protein-coupled receptor 34,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,-0.2,1.12,-0.1,0.332,-0.332,0.781,0,0,-1.7,1.1
ENSMUSG00000060579,FHIT,fragile histidine triad gene,nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|extracellular vesicular exosome|,"purine nucleotide metabolic process|DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|nucleotide metabolic process|diadenosine triphosphate catabolic process|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|intrinsic apoptotic signaling pathway by p53 class mediator|",nucleotide binding|catalytic activity|nickel cation binding|hydrolase activity|hydrolase activity|ubiquitin protein ligase binding|identical protein binding|bis(5'-adenosyl)-triphosphatase activity|bis(5'-adenosyl)-triphosphatase activity|,10,0,0,10,0.4,0.948,0.1,0.329,0.329,0.782,0,0,-1.3,1.7
ENSMUSG00000020390,UBE2B,ubiquitin-conjugating enzyme E2B,chromatin|nuclear chromatin|XY body|nucleus|replication fork|cytoplasm|plasma membrane|membrane|HULC complex|,protein polyubiquitination|in utero embryonic development|DNA repair|postreplication repair|maintenance of chromatin silencing|ubiquitin-dependent protein catabolic process|protein monoubiquitination|cellular response to DNA damage stimulus|spermatogenesis|sperm axoneme assembly|response to UV|positive regulation of reciprocal meiotic recombination|protein ubiquitination|regulation of histone modification|negative regulation of histone phosphorylation|histone H2A ubiquitination|response to drug|negative regulation of apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of cAMP-mediated signaling|protein stabilization|chiasma assembly|protein autoubiquitination|canonical Wnt signaling pathway|histone lysine demethylation|synaptonemal complex organization|protein K63-linked ubiquitination|protein K48-linked ubiquitination|protein K11-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|ubiquitin protein ligase binding|,10,-0.2,0.577,10,0,0,-0.1,0.328,-0.328,0.782,0,0,-1.7,1.2
ENSMUSG00000022504,CIITA,class II transactivator,nucleus|cell surface|PML body|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|phosphorylation|response to interferon-gamma|response to interferon-gamma|positive regulation of MHC class I biosynthetic process|positive regulation of MHC class II biosynthetic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|response to antibiotic|","nucleotide binding|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|ATP binding|GTP binding|protein C-terminus binding|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|kinase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|protein complex binding|activating transcription factor binding|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|transcription regulatory region DNA binding|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0,0,10,-0.3,1.67,-0.2,0.325,-0.325,0.783,0,0,-1.7,1.1
ENSMUSG00000036503,RNF13,ring finger protein 13,nucleus|cytoplasm|lysosome|lysosomal membrane|lysosomal membrane|endosome|membrane|integral component of membrane|late endosome membrane|,protein autoubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.8,1.92,10,-0.1,0.135,0.1,0.318,0.318,0.785,0,0,-1.1,2
ENSMUSG00000032698,LMO2,LIM domain only 2,nucleus|transcription factor complex|protein complex|,embryonic hemopoiesis|mRNA transcription from RNA polymerase II promoter|negative regulation of erythrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cellular response to thyroid hormone stimulus|,RNA polymerase II regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|protein binding|zinc ion binding|bHLH transcription factor binding|metal ion binding|cofactor binding|E-box binding|,10,0,0,10,-0.3,1.66,-0.2,0.317,-0.317,0.785,0,0,-1.7,1
ENSMUSG00000025964,ADAM23,a disintegrin and metallopeptidase domain 23,extracellular region|plasma membrane|membrane|integral component of membrane|,proteolysis|cell adhesion|,metalloendopeptidase activity|protein binding|metallopeptidase activity|zinc ion binding|,10,-0.1,0.308,10,-0.1,0.0389,-0.1,0.317,-0.317,0.785,0,0,-1.9,1
ENSMUSG00000036986,PML,promyelocytic leukemia,intracellular|nucleus|nucleus|nucleoplasm|cytoplasm|endosome|endoplasmic reticulum|cytosol|membrane|nuclear matrix|nuclear matrix|PML body|PML body|PML body|nuclear membrane|extrinsic component of endoplasmic reticulum membrane|,"response to hypoxia|response to hypoxia|regulation of protein phosphorylation|positive regulation of defense response to virus by host|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|protein complex assembly|protein targeting|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cell cycle arrest|cell cycle arrest|transforming growth factor beta receptor signaling pathway|common-partner SMAD protein phosphorylation|SMAD protein import into nucleus|cell aging|negative regulation of cell proliferation|negative regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to oxidative stress|response to UV|response to gamma radiation|regulation of calcium ion transport into cytosol|viral process|negative regulation of angiogenesis|negative regulation of angiogenesis|myeloid cell differentiation|negative regulation of cell growth|PML body organization|PML body organization|positive regulation of histone deacetylation|negative regulation of telomere maintenance via telomerase|endoplasmic reticulum calcium ion homeostasis|circadian regulation of gene expression|negative regulation of translation in response to oxidative stress|response to cytokine|regulation of circadian rhythm|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|entrainment of circadian clock by photoperiod|proteasome-mediated ubiquitin-dependent protein catabolic process|innate immune response|innate immune response|cell fate commitment|regulation of MHC class I biosynthetic process|negative regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|retinoic acid receptor signaling pathway|rhythmic process|protein stabilization|maintenance of protein location in nucleus|defense response to virus|negative regulation of telomerase activity|positive regulation of apoptotic process involved in mammary gland involution|branching involved in mammary gland duct morphogenesis|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|cellular response to interleukin-4|intrinsic apoptotic signaling pathway by p53 class mediator|cellular senescence|extrinsic apoptotic signaling pathway|negative regulation of viral release from host cell|negative regulation of viral release from host cell|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of double-strand break repair|regulation of RNA biosynthetic process|positive regulation of apoptotic signaling pathway|positive regulation of apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|",DNA binding|transcription coactivator activity|transcription coactivator activity|protein binding|zinc ion binding|ubiquitin protein ligase binding|SUMO binding|protein homodimerization activity|SMAD binding|metal ion binding|protein heterodimerization activity|cobalt ion binding|,10,-0.2,0.968,10,0,0,-0.1,0.317,-0.317,0.785,0,0,-1.2,1.7
ENSMUSG00000052516,ROBO2,roundabout homolog 2 (Drosophila),cell surface|membrane|integral component of membrane|axolemma|extracellular vesicular exosome|,metanephros development|ureteric bud development|ureteric bud development|chemotaxis|homophilic cell adhesion|signal transduction|multicellular organismal development|nervous system development|axon guidance|axon guidance|axon midline choice point recognition|olfactory bulb interneuron development|cell differentiation|retinal ganglion cell axon guidance|positive regulation of axonogenesis|negative regulation of negative chemotaxis|,protein binding|axon guidance receptor activity|identical protein binding|protein heterodimerization activity|,10,-0.1,0.196,10,-0.1,0.143,-0.1,0.309,-0.309,0.788,0,0,-1.7,1.1
ENSMUSG00000004655,AQP1,aquaporin 1,cell|nucleus|cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|brush border|brush border|basal plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|symbiont-containing vacuole|symbiont-containing vacuole membrane|axon|brush border membrane|nuclear membrane|dense core granule membrane|neuronal cell body membrane|sarcolemma|neuron projection|axon terminus|apical part of cell|extracellular vesicular exosome|extracellular vesicular exosome|,glomerular filtration|renal water transport|cGMP biosynthetic process|transport|potassium ion transport|water transport|water transport|water transport|water transport|water transport|cell volume homeostasis|positive regulation of lamellipodium assembly|positive regulation of epithelial cell migration|carbon dioxide transport|organic cation transport|ammonium transport|glycerol transport|sensory perception of pain|cellular homeostasis|water homeostasis|nitric oxide transport|positive regulation of cell migration|establishment or maintenance of actin cytoskeleton polarity|secretion by cell|secretory granule organization|cellular response to stress|carbohydrate transmembrane transport|cellular response to UV|transepithelial water transport|carbon dioxide transmembrane transport|wound healing|response to drug|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|lipid digestion|positive regulation of angiogenesis|positive regulation of saliva secretion|positive regulation of fibroblast proliferation|camera-type eye morphogenesis|corticotropin secretion|transmembrane transport|renal water absorption|renal water absorption|cellular response to hydrogen peroxide|cellular response to inorganic substance|cellular response to mechanical stimulus|cellular response to copper ion|cellular response to mercury ion|cellular response to retinoic acid|cellular response to cAMP|cellular response to hypoxia|cellular response to salt stress|cellular hyperosmotic response|cellular response to dexamethasone stimulus|cellular response to nitric oxide|potassium ion transmembrane transport|potassium ion transmembrane transport|ammonium transmembrane transport|maintenance of symbiont-containing vacuole by host|maintenance of symbiont-containing vacuole by host|,transporter activity|intracellular cGMP activated cation channel activity|potassium channel activity|water transmembrane transporter activity|water transmembrane transporter activity|ammonium transmembrane transporter activity|potassium ion transmembrane transporter activity|glycerol transmembrane transporter activity|water channel activity|water channel activity|transmembrane transporter activity|nitric oxide transmembrane transporter activity|carbon dioxide transmembrane transporter activity|ephrin receptor binding|,10,0.7,1.92,10,0,0,0.1,0.307,0.307,0.788,0,0,-1,2
ENSMUSG00000048388,FAM171B,"family with sequence similarity 171, member B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.151,10,-0.2,1.03,-0.1,0.304,-0.304,0.789,0,0,-1.5,1.3
ENSMUSG00000030336,CD27,CD27 antigen,cell|external side of plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,apoptotic process|B cell proliferation|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of interferon-gamma biosynthetic process|positive regulation of T cell differentiation|positive regulation of JNK cascade|immunoglobulin secretion|negative regulation of T cell apoptotic process|extrinsic apoptotic signaling pathway|,protein binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|,10,-0.1,0.138,10,1,2.53,0.2,0.303,0.303,0.789,0,0,-0.5,2
ENSMUSG00000009097,TBX1,T-box 1,nucleus|nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|blood vessel development|blood vessel development|patterning of blood vessels|cell fate specification|cell fate specification|neural crest cell migration|positive regulation of protein phosphorylation|lymph vessel development|blood vessel remodeling|positive regulation of mesenchymal cell proliferation|heart morphogenesis|outflow tract septum morphogenesis|outflow tract morphogenesis|outflow tract morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|determination of left/right symmetry|pattern specification process|pattern specification process|mesoderm development|heart development|heart development|heart development|heart development|muscle organ development|sensory perception of sound|cell proliferation|positive regulation of cell proliferation|anterior/posterior pattern specification|anterior/posterior pattern specification|vagus nerve morphogenesis|epithelial cell differentiation|thyroid gland development|thyroid gland development|social behavior|aorta morphogenesis|aorta morphogenesis|ear morphogenesis|inner ear morphogenesis|outer ear morphogenesis|middle ear morphogenesis|odontogenesis of dentin-containing tooth|muscle cell fate commitment|positive regulation of MAPK cascade|tongue morphogenesis|cellular response to fibroblast growth factor stimulus|negative regulation of cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|retinoic acid receptor signaling pathway|blood vessel morphogenesis|thymus development|thymus development|thymus development|muscle organ morphogenesis|embryonic cranial skeleton morphogenesis|embryonic viscerocranium morphogenesis|embryonic viscerocranium morphogenesis|semicircular canal morphogenesis|artery morphogenesis|artery morphogenesis|positive regulation of epithelial cell proliferation|parathyroid gland development|parathyroid gland development|soft palate development|soft palate development|pharyngeal system development|pharyngeal system development|pharyngeal system development|pharyngeal system development|face morphogenesis|muscle tissue morphogenesis|coronary artery morphogenesis|coronary artery morphogenesis|enamel mineralization|otic vesicle morphogenesis|positive regulation of secondary heart field cardioblast proliferation|cochlea morphogenesis|cochlea morphogenesis|mesenchymal cell apoptotic process|regulation of organ morphogenesis|regulation of organ morphogenesis|positive regulation of tongue muscle cell differentiation|negative regulation of mesenchymal cell apoptotic process|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding|,10,-0.1,0.0338,10,-0.1,0.296,-0.1,0.302,-0.302,0.79,0,0,-1.7,1.2
ENSMUSG00000028191,BCL10,B cell leukemia/lymphoma 10,immunological synapse|intracellular|nucleus|cytoplasm|cytoplasm|cytoplasm|lysosome|cytosol|cytosol|cytoplasmic microtubule|membrane|CBM complex|T cell receptor complex|protein complex|membrane raft|lipopolysaccharide receptor complex|perinuclear region of cytoplasm|,"B cell apoptotic process|neural tube closure|negative regulation of mature B cell apoptotic process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cellular defense response|I-kappaB kinase/NF-kappaB signaling|I-kappaB kinase/NF-kappaB signaling|cell death|response to fungus|immunoglobulin mediated immune response|positive regulation of protein ubiquitination|response to food|positive regulation of phosphorylation|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of interleukin-8 biosynthetic process|mast cell activation|positive regulation of transcription, DNA-templated|T cell receptor signaling pathway|regulation of T cell receptor signaling pathway|positive regulation of T cell activation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein oligomerization|protein homooligomerization|protein heterooligomerization|T cell apoptotic process|positive regulation of execution phase of apoptosis|positive regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|",protease binding|transcription coactivator activity|protein binding|protein C-terminus binding|transcription factor binding|cysteine-type endopeptidase activator activity involved in apoptotic process|kinase activator activity|enzyme binding|kinase binding|protein kinase binding|ubiquitin protein ligase binding|protein homodimerization activity|ubiquitin binding|protein kinase B binding|protein self-association|protein heterodimerization activity|NF-kappaB binding|NF-kappaB binding|,10,0,0,10,-0.1,0.53,-0.1,0.3,-0.3,0.79,0,0,-1.8,1.1
ENSMUSG00000024304,CDH2,cadherin 2,plasma membrane|cell-cell junction|cell-cell junction|adherens junction|cell-cell adherens junction|fascia adherens|fascia adherens|intercalated disc|intercalated disc|membrane|integral component of membrane|apical plasma membrane|catenin complex|lamellipodium|T-tubule|protein complex|synapse|synapse|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|synapse assembly|single organismal cell-cell adhesion|calcium-dependent cell-cell adhesion|calcium-dependent cell-cell adhesion|cell migration|regulation of myelination|regulation of protein localization|regulation of Rho protein signal transduction|positive regulation of MAPK cascade|blood vessel morphogenesis|regulation of axonogenesis|striated muscle cell differentiation|protein heterooligomerization|negative regulation of canonical Wnt signaling pathway|,calcium ion binding|protein binding|beta-catenin binding|protein kinase binding|protein phosphatase binding|protein complex binding|alpha-catenin binding|gamma-catenin binding|metal ion binding|nitric-oxide synthase binding|,10,0,0,10,-0.4,1.5,-0.1,0.298,-0.298,0.791,0,0,-1.8,0.9
ENSMUSG00000047281,SFN,stratifin,extracellular region|nucleus|cytoplasm|cytoplasm|extracellular vesicular exosome|,regulation of cyclin-dependent protein serine/threonine kinase activity|release of cytochrome c from mitochondria|keratinocyte development|intrinsic apoptotic signaling pathway in response to DNA damage|regulation of epidermal cell division|negative regulation of keratinocyte proliferation|keratinocyte differentiation|positive regulation of cell growth|keratinization|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|skin development|skin development|positive regulation of epidermal cell differentiation|positive regulation of protein export from nucleus|regulation of cell cycle|establishment of skin barrier|,protein binding|protein kinase binding|protein domain specific binding|phosphoprotein binding|,10,-0.3,0.964,10,0,0,-0.1,0.298,-0.298,0.791,0,0,-1.4,1.7
ENSMUSG00000030970,CTBP2,C-terminal binding protein 2,nucleus|nucleus|transcriptional repressor complex|cell junction|synapse|,"transcription, DNA-templated|regulation of transcription, DNA-templated|metabolic process|cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|white fat cell differentiation|oxidation-reduction process|","transcription corepressor activity|transcription corepressor activity|protein binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|NAD binding|",10,0,0,10,-0.1,0.441,-0.1,0.292,-0.292,0.792,0,0,-1.6,1.3
ENSMUSG00000025147,MOB2,MOB kinase activator 2,nucleus|nucleolus|cytoplasm|cytoplasm|neuron projection terminus|,positive regulation of protein phosphorylation|positive regulation of neuron projection development|actin cytoskeleton organization|,molecular_function|metal ion binding|,10,-0.1,0.164,10,-0.3,0.371,-0.1,0.286,-0.286,0.794,0,0,-1.9,0.8
ENSMUSG00000060181,SLC35E3,"solute carrier family 35, member E3",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.539,10,0,0,0.1,0.286,0.286,0.794,0,0,-1.3,1.6
ENSMUSG00000020044,TIMP3,tissue inhibitor of metalloproteinase 3,extracellular region|proteinaceous extracellular matrix|basement membrane|nucleus|cytoplasm|extracellular matrix|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of proteolysis|negative regulation of membrane protein ectodomain proteolysis|cellular response to organic substance|,enzyme inhibitor activity|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|metal ion binding|,10,0.3,0.588,10,-0.1,0.291,-0.1,0.278,-0.278,0.796,0,0,-1.2,1.7
ENSMUSG00000027478,DNMT3B,DNA methyltransferase 3B,"chromosome, centromeric region|heterochromatin|nucleus|nucleus|nuclear heterochromatin|cytoplasm|intracellular membrane-bounded organelle|","negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|DNA methylation|DNA methylation|methylation-dependent chromatin silencing|regulation of gene expression by genetic imprinting|DNA methylation on cytosine within a CG sequence|positive regulation of gene expression|protein complex localization|methylation|positive regulation of neuron differentiation|negative regulation of gene expression, epigenetic|negative regulation of transcription, DNA-templated|S-adenosylhomocysteine metabolic process|S-adenosylmethioninamine metabolic process|positive regulation of histone H3-K4 methylation|negative regulation of histone H3-K9 methylation|cellular response to amino acid stimulus|C-5 methylation of cytosine|","DNA binding|DNA binding|transcription corepressor activity|DNA (cytosine-5-)-methyltransferase activity|DNA (cytosine-5-)-methyltransferase activity|DNA (cytosine-5-)-methyltransferase activity|protein binding|methyltransferase activity|transferase activity|unmethylated CpG binding|metal ion binding|DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates|",10,0.1,0.393,10,0,0,0.1,0.271,0.271,0.798,0,0,-1.7,1.2
ENSMUSG00000034613,PPM1H,protein phosphatase 1H (PP2C domain containing),cellular_component|,biological_process|,molecular_function|catalytic activity|phosphoprotein phosphatase activity|hydrolase activity|,10,0.3,2.18,10,-0.1,0.254,-0.1,0.27,-0.27,0.798,0,0,-1.2,1.6
ENSMUSG00000022969,IL10RB,"interleukin 10 receptor, beta",membrane|integral component of membrane|extracellular vesicular exosome|,cytokine-mediated signaling pathway|,interleukin-10 receptor activity|protein binding|,7,0,0,7,0.2,0.591,0.1,0.27,0.27,0.798,0,0,-1.1,2
ENSMUSG00000014030,PAX5,paired box 5,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|nervous system development|organ morphogenesis|cell differentiation|skeletal muscle cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of histone H3-K9 methylation|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0,0,10,-0.4,1.41,-0.1,0.269,-0.269,0.798,0,0,-1.9,0.8
ENSMUSG00000032532,CCK,cholecystokinin,extracellular region|extracellular space|axon|dendrite|neuronal cell body|axon initial segment|terminal bouton|axon hillock|perikaryon|,behavioral fear response|neuron migration|release of cytochrome c from mitochondria|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|protein kinase C-activating G-protein coupled receptor signaling pathway|axonogenesis|positive regulation of cell proliferation|negative regulation of appetite|positive regulation of protein oligomerization|eating behavior|eating behavior|positive regulation of apoptotic process|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of mitochondrial depolarization|regulation of sensory perception of pain|,hormone activity|neuropeptide hormone activity|neuropeptide hormone activity|protein binding|,10,0,0,10,0.2,0.575,0.1,0.266,0.266,0.799,0,0,-1.1,1.7
ENSMUSG00000041523,UPK2,uroplakin 2,plasma membrane|membrane|integral component of membrane|apical plasma membrane|integral component of endoplasmic reticulum membrane|extracellular vesicular exosome|,epithelial cell differentiation|membrane organization|,None,10,1.1,3.39,10,0,0,1,0.26,0.26,0.801,0,0,-0.3,2
ENSMUSG00000039530,TUSC3,tumor suppressor candidate 3,mitochondrion|endoplasmic reticulum|oligosaccharyltransferase complex|membrane|integral component of membrane|,transport|magnesium ion transport|ion transmembrane transport|cell redox homeostasis|cognition|,magnesium ion transmembrane transporter activity|,9,0,0,9,-0.2,0.605,-0.1,0.256,-0.256,0.802,0,0,-1.7,1.2
ENSMUSG00000022261,SDC2,syndecan 2,membrane|integral component of membrane|neuronal cell body|synapse|,nervous system development|cell differentiation|regulation of dendrite morphogenesis|,protein binding|cytoskeletal protein binding|PDZ domain binding|,10,0,0,10,0.4,2.62,0.3,0.254,0.254,0.803,0,0,-1,1.7
ENSMUSG00000024912,FOSL1,fos-like antigen 1,nucleus|cytosol|presynaptic membrane|neuron projection|intracellular membrane-bounded organelle|,"in utero embryonic development|regulation of transcription, DNA-templated|vitellogenesis|negative regulation of cell proliferation|cellular response to extracellular stimulus|positive regulation of apoptotic process|positive regulation of cell cycle|positive regulation of sequence-specific DNA binding transcription factor activity|placenta blood vessel development|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.2,0.802,0.1,0.254,0.254,0.803,0,0,-0.8,2
ENSMUSG00000022884,EIF4A2,eukaryotic translation initiation factor 4A2,None,translation|translational initiation|,nucleotide binding|nucleic acid binding|RNA binding|translation initiation factor activity|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,0,0,9,-0.7,1.35,-0.3,0.254,-0.254,0.803,0,0,-2,0.5
ENSMUSG00000020826,NOS2,"nitric oxide synthase 2, inducible",extracellular space|intracellular|intracellular|nucleus|cytoplasm|cytoplasm|peroxisome|cytosol|cytosol|vesicle membrane|cortical cytoskeleton|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,response to hypoxia|arginine catabolic process|arginine catabolic process|superoxide metabolic process|nitric oxide biosynthetic process|nitric oxide biosynthetic process|inflammatory response|nitric oxide mediated signal transduction|negative regulation of gene expression|negative regulation of gene expression|peptidyl-cysteine S-nitrosylation|positive regulation of guanylate cyclase activity|response to lipopolysaccharide|regulation of cell proliferation|negative regulation of protein catabolic process|defense response to bacterium|defense response to bacterium|negative regulation of blood pressure|regulation of protein kinase activity|positive regulation of vasodilation|regulation of insulin secretion|positive regulation of killing of cells of other organism|oxidation-reduction process|cellular response to lipopolysaccharide|cellular response to interferon-gamma|,actin binding|NADPH-hemoprotein reductase activity|nitric-oxide synthase activity|nitric-oxide synthase activity|receptor binding|iron ion binding|protein binding|calmodulin binding|beta-catenin binding|cAMP-dependent protein kinase regulator activity|FMN binding|oxidoreductase activity|protein kinase binding|heme binding|tetrahydrobiopterin binding|arginine binding|protein homodimerization activity|protein homodimerization activity|cadherin binding|metal ion binding|flavin adenine dinucleotide binding|NADP binding|nitric-oxide synthase binding|Hsp90 protein binding|,10,-0.1,0.135,10,-0.1,0.143,-0.1,0.253,-0.253,0.803,0,0,-1.6,1.3
ENSMUSG00000043822,ADAMTSL5,ADAMTS-like 5,microfibril|extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular matrix|,biological_process|,heparin binding|,10,0,0,10,0.1,0.339,0.1,0.248,0.248,0.804,0,0,-0.9,1.9
ENSMUSG00000029838,PTN,pleiotrophin,extracellular region|proteinaceous extracellular matrix|endoplasmic reticulum|,ossification|learning|bone mineralization|positive regulation of cell division|,growth factor activity|heparin binding|,10,0,0,10,-0.2,0.823,-0.1,0.247,-0.247,0.805,0,0,-1.4,1.5
ENSMUSG00000001482,DEF8,differentially expressed in FDCP 8,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|zinc ion binding|metal ion binding|,10,0.2,0.538,10,0,0,0.1,0.246,0.246,0.805,0,0,-1.2,1.6
ENSMUSG00000024301,KIFC5B,kinesin family member C5B,membrane|,biological_process|,molecular_function|,10,0,0,10,0.2,0.855,0.1,0.245,0.245,0.805,0,0,-1.2,1.6
ENSMUSG00000026012,CD28,CD28 antigen,immunological synapse|plasma membrane|external side of plasma membrane|external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|membrane raft|,positive regulation of inflammatory response to antigenic stimulus|immune response|positive regulation of signal transduction|positive regulation of phosphatidylinositol 3-kinase signaling|T cell costimulation|T cell costimulation|T cell costimulation|T cell costimulation|positive regulation of T cell proliferation|positive regulation of T cell proliferation|positive regulation of T cell proliferation|T cell activation|negative thymic T cell selection|regulatory T cell differentiation|positive regulation of interleukin-2 biosynthetic process|positive regulation of interleukin-2 biosynthetic process|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of alpha-beta T cell proliferation|positive regulation of alpha-beta T cell proliferation|positive regulation of isotype switching to IgG isotypes|T cell receptor signaling pathway|positive regulation of protein kinase B signaling|apoptotic signaling pathway|,protease binding|SH3/SH2 adaptor activity|protein homodimerization activity|,9,0,0,9,-0.6,1.62,-0.2,0.245,-0.245,0.805,0,0,-1.8,1.3
ENSMUSG00000032009,SESN3,sestrin 3,cellular_component|nucleus|,response to insulin|glucose homeostasis|regulation of protein kinase B signaling|regulation of response to reactive oxygen species|,molecular_function|,10,0.3,1.25,10,-0.2,1.21,-0.1,0.243,-0.243,0.806,0,0,-1,1.7
ENSMUSG00000032612,USP4,ubiquitin specific peptidase 4 (proto-oncogene),nucleus|cytoplasm|plasma membrane|,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|negative regulation of protein ubiquitination|regulation of protein stability|protein localization to cell surface|,ubiquitin thiolesterase activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|adenosine receptor binding|ubiquitinyl hydrolase activity|identical protein binding|metal ion binding|,10,0.2,0.425,10,-0.2,0.627,-0.1,0.241,-0.241,0.806,0,0,-1.5,1.3
ENSMUSG00000024790,SAC3D1,SAC3 domain containing 1,nucleus|cytoplasm|centrosome|spindle|cytoskeleton|microtubule cytoskeleton|,cell cycle|mitotic nuclear division|negative regulation of JAK-STAT cascade|regulation of immune response|spindle assembly|centrosome duplication|cell division|,protein binding|,10,0.3,1.73,10,-0.1,0.0833,0.1,0.238,0.238,0.807,0,0,-0.9,1.8
ENSMUSG00000033880,LGALS3BP,"lectin, galactoside-binding, soluble, 3 binding protein",extracellular region|proteinaceous extracellular matrix|extracellular space|membrane|extracellular matrix|extracellular vesicular exosome|blood microparticle|,receptor-mediated endocytosis|cell adhesion|,scavenger receptor activity|scavenger receptor activity|protein binding|,10,-0.2,0.481,10,0,0,-0.1,0.237,-0.237,0.807,0,0,-1.5,1.4
ENSMUSG00000034457,EDA2R,ectodysplasin A2 receptor,intracellular|integral component of plasma membrane|membrane|integral component of membrane|,multicellular organismal development|programmed cell death|cell differentiation|positive regulation of JNK cascade|positive regulation of NF-kappaB transcription factor activity|intrinsic apoptotic signaling pathway by p53 class mediator|,receptor activity|,10,0.2,0.277,10,-0.2,0.425,-0.1,0.236,-0.236,0.807,0,0,-1.4,1.5
ENSMUSG00000014773,DLL1,delta-like 1 (Drosophila),plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,in utero embryonic development|somitogenesis|somite specification|heart looping|cell communication|Notch signaling pathway|Notch signaling pathway|cell-cell signaling|multicellular organismal development|determination of left/right symmetry|compartment pattern specification|nervous system development|organ morphogenesis|auditory receptor cell fate commitment|cell differentiation|negative regulation of interleukin-10 production|inner ear morphogenesis|odontogenesis of dentin-containing tooth|auditory receptor cell differentiation|negative regulation of cell differentiation|negative regulation of auditory receptor cell differentiation|negative regulation of myeloid cell differentiation|negative regulation of neuron differentiation|positive regulation of Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|inner ear development|regulation of neurogenesis|Notch signaling involved in heart development|left/right axis specification|,Notch binding|Notch binding|calcium ion binding|protein binding|,10,0.4,0.83,10,0.1,0.104,0.2,0.234,0.234,0.808,0,0,-0.8,1.9
ENSMUSG00000028602,TNFRSF8,"tumor necrosis factor receptor superfamily, member 8",membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|positive regulation of tumor necrosis factor biosynthetic process|positive regulation of apoptotic process|positive regulation of TRAIL biosynthetic process|positive regulation of NF-kappaB transcription factor activity|,transmembrane signaling receptor activity|,10,0.3,0.656,10,0.1,0.0487,0.1,0.234,0.234,0.808,0,0,-0.9,1.9
ENSMUSG00000024892,PCX,pyruvate carboxylase,mitochondrion|mitochondrion|mitochondrial inner membrane|,pyruvate metabolic process|gluconeogenesis|oxaloacetate metabolic process|lipid metabolic process|metabolic process|,nucleotide binding|DNA binding|catalytic activity|biotin carboxylase activity|pyruvate carboxylase activity|ATP binding|biotin binding|ligase activity|carboxylic acid binding|metal ion binding|,10,0.2,0.471,10,-0.1,0.128,0.2,0.233,0.233,0.808,0,0,-1,1.7
ENSMUSG00000038780,SMURF1,SMAD specific E3 ubiquitin protein ligase 1,nucleus|cytoplasm|cytoplasm|plasma membrane|membrane|axon|neuronal cell body|extracellular vesicular exosome|,protein polyubiquitination|protein export from nucleus|transforming growth factor beta receptor signaling pathway|protein ubiquitination|protein ubiquitination|cell differentiation|cell differentiation|negative regulation of ossification|BMP signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|ubiquitin-dependent SMAD protein catabolic process|receptor catabolic process|protein localization to cell surface|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|I-SMAD binding|R-SMAD binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,1.11,10,0,0,0.1,0.232,0.232,0.809,0,0,-1.6,1.3
ENSMUSG00000040046,TPH1,tryptophan hydroxylase 1,neuron projection|,metabolic process|aromatic amino acid family metabolic process|negative regulation of ossification|serotonin biosynthetic process|bone remodeling|oxidation-reduction process|mammary gland alveolus development|,"monooxygenase activity|tryptophan 5-monooxygenase activity|tryptophan 5-monooxygenase activity|iron ion binding|oxidoreductase activity|amino acid binding|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen|metal ion binding|",10,0.3,0.351,10,0.1,0.174,0.1,0.231,0.231,0.809,0,0,-0.7,1.9
ENSMUSG00000042303,SGSM3,small G protein signaling modulator 3,cytoplasm|gap junction|,cell cycle|cell cycle arrest|regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|positive regulation of protein catabolic process|regulation of catalytic activity|,small GTPase regulator activity|Rab GTPase activator activity|protein binding|Rab GTPase binding|,10,-0.1,0.397,10,-1,1.21,-0.1,0.23,-0.23,0.809,0,0,-2,0.7
ENSMUSG00000028017,EGF,epidermal growth factor,extracellular space|extracellular space|intracellular|lysosomal membrane|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,"activation of MAPKK activity|angiogenesis|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|STAT protein import into nucleus|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of peptidyl-threonine phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of cerebellar granule cell precursor proliferation|positive regulation of catenin import into nucleus|positive regulation of phosphorylation|positive regulation of DNA binding|positive regulation of MAP kinase activity|positive regulation of epidermal growth factor-activated receptor activity|positive regulation of mitosis|positive regulation of transcription, DNA-templated|branching morphogenesis of an epithelial tube|regulation of protein secretion|regulation of peptidyl-tyrosine phosphorylation|negative regulation of secretion|regulation of protein transport|mammary gland alveolus development|ERK1 and ERK2 cascade|regulation of calcium ion import|negative regulation of cholesterol efflux|positive regulation of hyaluronan biosynthetic process|regulation of protein localization to cell surface|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|",epidermal growth factor receptor binding|epidermal growth factor receptor binding|calcium ion binding|protein binding|growth factor activity|,10,0,0,10,0.2,0.697,0.1,0.226,0.226,0.81,0,0,-1.3,1.5
ENSMUSG00000003545,FOSB,FBJ osteosarcoma oncogene B,nucleus|,"regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular response to calcium ion|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.1,0.198,10,0.2,0.102,0.1,0.226,0.226,0.81,0,0,-1,1.7
ENSMUSG00000001604,TCEA3,"transcription elongation factor A (SII), 3",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of DNA-templated transcription, elongation|",nucleic acid binding|DNA binding|zinc ion binding|metal ion binding|,10,0.1,0.536,10,0,0,0.1,0.225,0.225,0.81,0,0,-1.1,1.7
ENSMUSG00000081683,FZD10,frizzled homolog 10 (Drosophila),cytoplasm|cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|cell projection|,vasculature development|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|multicellular organismal development|brain development|gonad development|embryo development|Wnt signaling pathway|positive regulation of Rac GTPase activity|regulation of actin cytoskeleton organization|negative regulation of Rho GTPase activity|non-canonical Wnt signaling pathway via JNK cascade|positive regulation of JUN kinase activity|canonical Wnt signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|Wnt-protein binding|PDZ domain binding|Wnt-activated receptor activity|,10,0,0,10,-0.1,0.261,-0.1,0.223,-0.223,0.811,0,0,-1.5,1.3
ENSMUSG00000025407,GLI1,GLI-Kruppel family member GLI1,nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|cytosol|cilium|intracellular membrane-bounded organelle|primary cilium|,"osteoblast differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|signal transduction|smoothened signaling pathway|smoothened signaling pathway|smoothened signaling pathway|multicellular organismal development|spermatogenesis|ventral midline development|positive regulation of cell proliferation|epidermal cell differentiation|dorsal/ventral pattern formation|proximal/distal pattern formation|cerebellar cortex morphogenesis|smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation|pituitary gland development|cell differentiation|lung development|positive regulation of DNA replication|positive regulation of smoothened signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|notochord regression|negative regulation of canonical Wnt signaling pathway|",nucleic acid binding|DNA binding|DNA binding|chromatin binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|microtubule binding|transcription regulatory region DNA binding|metal ion binding|,10,0.1,0.103,10,0.1,0.138,0.1,0.22,0.22,0.811,0,0,-0.9,1.9
ENSMUSG00000033826,DNAH8,"dynein, axonemal, heavy chain 8",cytoplasm|cytoskeleton|microtubule|cilium|dynein complex|cell projection|sperm principal piece|,microtubule-based movement|biological_process|,nucleotide binding|molecular_function|motor activity|microtubule motor activity|ATP binding|ATPase activity|,10,0.1,0.284,10,0.2,0.076,0.2,0.217,0.217,0.812,0,0,-0.7,2
ENSMUSG00000022546,GPT,"glutamic pyruvic transaminase, soluble",cytoplasm|extracellular vesicular exosome|,biosynthetic process|,catalytic activity|L-alanine:2-oxoglutarate aminotransferase activity|transaminase activity|transferase activity|pyridoxal phosphate binding|,10,0,0,10,1.1,2.57,0.1,0.216,0.216,0.813,0,0,-0.9,2
ENSMUSG00000031803,B3GNT3,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3",cellular_component|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|biological_process|,"molecular_function|galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity|",10,0,0,10,0.1,0.514,0.1,0.215,0.215,0.813,0,0,-1,1.9
ENSMUSG00000022130,TGDS,"TDP-glucose 4,6-dehydratase",cellular_component|,biological_process|nucleotide-sugar metabolic process|,"molecular_function|catalytic activity|dTDP-glucose 4,6-dehydratase activity|lyase activity|coenzyme binding|",10,0.1,0.299,10,-0.1,0.642,-0.1,0.214,-0.214,0.813,0,0,-1.4,1.5
ENSMUSG00000006389,MPL,myeloproliferative leukemia virus oncogene,plasma membrane|membrane|integral component of membrane|,regulation of chemokine production|homeostasis of number of cells|,cytokine receptor activity|,10,0,0,10,0.2,0.622,0.1,0.214,0.214,0.813,0,0,-1.3,1.5
ENSMUSG00000031239,ITM2A,integral membrane protein 2A,membrane|integral component of membrane|,None,None,10,-0.7,1.31,10,0,0,-0.1,0.209,-0.209,0.814,0,0,-2,0.7
ENSMUSG00000071658,GNG3,"guanine nucleotide binding protein (G protein), gamma 3",heterotrimeric G-protein complex|plasma membrane|membrane|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|,G-protein coupled receptor binding|GTPase activity|signal transducer activity|type 1 angiotensin receptor binding|,10,0,0,10,0.1,0.304,0.1,0.209,0.209,0.814,0,0,-1.5,1.4
ENSMUSG00000026826,NR4A2,"nuclear receptor subfamily 4, group A, member 2",nucleus|nucleus|cytoplasm|,"response to hypoxia|neuron migration|response to amphetamine|transcription, DNA-templated|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|nervous system development|adult locomotory behavior|post-embryonic development|response to inorganic substance|gene expression|regulation of gene expression|death|response to insecticide|central nervous system projection neuron axonogenesis|central nervous system neuron differentiation|habenula development|neuron differentiation|intracellular receptor signaling pathway|cellular response to extracellular stimulus|cellular response to extracellular stimulus|cellular response to oxidative stress|regulation of dopamine metabolic process|dopamine biosynthetic process|dopamine metabolic process|neuron maturation|positive regulation of catalytic activity|steroid hormone mediated signaling pathway|negative regulation of neuron apoptotic process|regulation of respiratory gaseous exchange|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|general adaptation syndrome|dopaminergic neuron differentiation|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,0,0,10,-0.4,0.766,-0.1,0.205,-0.205,0.815,0,0,-1.9,0.9
ENSMUSG00000031551,IDO1,"indoleamine 2,3-dioxygenase 1",cytoplasm|cytosol|smooth muscle contractile fiber|stereocilium bundle|,cytokine production involved in inflammatory response|positive regulation of T cell tolerance induction|positive regulation of chronic inflammatory response|positive regulation of type 2 immune response|tryptophan catabolic process|defense response|inflammatory response|tryptophan catabolic process to kynurenine|tryptophan catabolic process to kynurenine|response to lipopolysaccharide|negative regulation of interleukin-10 production|positive regulation of interleukin-12 production|multicellular organismal response to stress|kynurenic acid biosynthetic process|swimming behavior|negative regulation of T cell proliferation|positive regulation of apoptotic process|negative regulation of activated T cell proliferation|oxidation-reduction process|negative regulation of T cell apoptotic process|,"tryptophan 2,3-dioxygenase activity|tryptophan 2,3-dioxygenase activity|protein binding|oxidoreductase activity|amino acid binding|oxygen binding|heme binding|indoleamine 2,3-dioxygenase activity|metal ion binding|dioxygenase activity|",10,0,0,10,-0.2,0.585,-0.1,0.203,-0.203,0.816,0,0,-1.7,1.1
ENSMUSG00000008822,ACYP1,"acylphosphatase 1, erythrocyte (common) type",extracellular vesicular exosome|,biological_process|,acylphosphatase activity|hydrolase activity|,10,-0.1,0.294,10,0.1,0.278,0.1,0.202,0.202,0.816,0,0,-1.3,1.6
ENSMUSG00000037032,APBB1,"amyloid beta (A4) precursor protein-binding, family B, member 1",nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|membrane|lamellipodium|growth cone|presynaptic membrane|cell projection|dendritic spine|protein complex|synapse|postsynaptic membrane|perinuclear region of cytoplasm|,"neuron migration|double-strand break repair|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|cell cycle arrest|axon guidance|visual learning|chromatin modification|actin filament-based movement|extracellular matrix organization|negative regulation of cell growth|positive regulation of apoptotic process|histone H4 acetylation|negative regulation of neuron differentiation|positive regulation of DNA repair|positive regulation of DNA repair|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein secretion|negative regulation of thymidylate synthase biosynthetic process|protein stabilization|",beta-amyloid binding|beta-amyloid binding|chromatin binding|protein binding|transcription factor binding|protein complex binding|histone acetyltransferase binding|histone binding|proline-rich region binding|,10,0.1,0.476,10,-0.1,0.176,0.1,0.196,0.196,0.818,0,0,-1.2,1.6
ENSMUSG00000032624,EML4,echinoderm microtubule associated protein like 4,cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|membrane|mitotic spindle|,negative regulation of microtubule depolymerization|,molecular_function|,10,0,0,10,-0.2,0.51,-0.1,0.193,-0.193,0.819,0,0,-1.4,1.6
ENSMUSG00000023186,VWA5A,von Willebrand factor A domain containing 5A,None,biological_process|,molecular_function|,10,-0.1,0.321,10,0.2,0.645,-0.1,0.193,-0.193,0.819,0,0,-0.9,1.8
ENSMUSG00000030093,WNT7A,"wingless-type MMTV integration site family, member 7A",extracellular region|proteinaceous extracellular matrix|extracellular space|cell|cell surface|extracellular matrix|,"embryonic axis specification|cartilage condensation|chondrocyte differentiation|signal transduction|cell-cell signaling|neurotransmitter secretion|multicellular organismal development|asymmetric protein localization|positive regulation of cell proliferation|organ morphogenesis|dorsal/ventral pattern formation|skeletal muscle satellite cell activation|skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration|Wnt signaling pathway|cerebellar granule cell differentiation|cell proliferation in forebrain|central nervous system vasculogenesis|establishment of cell polarity|embryonic limb morphogenesis|regulation of axon diameter|somatic stem cell maintenance|embryonic forelimb morphogenesis|embryonic forelimb morphogenesis|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic hindlimb morphogenesis|forelimb morphogenesis|hindlimb morphogenesis|non-canonical Wnt signaling pathway|Wnt signaling pathway involved in wound healing, spreading of epidermal cells|regulation of cell proliferation|embryonic digit morphogenesis|negative regulation of apoptotic process|skin morphogenesis|response to estrogen|cell fate commitment|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|positive regulation of JNK cascade|somatic stem cell division|reproductive structure development|skeletal system morphogenesis|stem cell development|negative regulation of neurogenesis|regulation of axonogenesis|synapse organization|synapse organization|cartilage development|positive regulation of synapse assembly|positive regulation of synapse assembly|palate development|positive regulation of epithelial cell proliferation involved in wound healing|uterus development|oviduct development|canonical Wnt signaling pathway|canonical Wnt signaling pathway|limb development|uterus morphogenesis|positive regulation of canonical Wnt signaling pathway|positive regulation of receptor activity|",receptor binding|receptor binding|frizzled binding|frizzled binding|cytokine activity|protein binding|receptor agonist activity|,10,0.1,0.348,10,0,0,0.1,0.192,0.192,0.819,0,0,-1.2,1.7
ENSMUSG00000059939,9430015G10RIK,RIKEN cDNA 9430015G10 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.386,10,0,0,-0.1,0.189,-0.189,0.82,0,0,-1.7,1.2
ENSMUSG00000020647,NCOA1,nuclear receptor coactivator 1,nuclear chromatin|nucleus|cytoplasm|neuron projection|,"positive regulation of transcription from RNA polymerase II promoter by galactose|positive regulation of transcription from RNA polymerase II promoter by galactose|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|response to estradiol|response to retinoic acid|response to progesterone|cellular response to hormone stimulus|positive regulation of apoptotic process|histone H4 acetylation|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of female receptivity|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|male mating behavior|labyrinthine layer morphogenesis|regulation of cellular response to drug|regulation of RNA biosynthetic process|","RNA polymerase II regulatory region DNA binding|DNA binding|chromatin binding|transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|histone acetyltransferase activity|signal transducer activity|protein binding|transcription factor binding|transcription factor binding|transferase activity|transferase activity, transferring acyl groups|ligand-dependent nuclear receptor binding|enzyme binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|protein complex binding|progesterone receptor binding|nuclear hormone receptor binding|retinoic acid receptor binding|retinoid X receptor binding|protein dimerization activity|protein N-terminus binding|",10,-0.5,2.16,10,0.1,0.248,0.1,0.188,0.188,0.82,0,0,-2,0.8
ENSMUSG00000013622,ATRAID,all-trans retinoic acid induced differentiation factor,nucleus|nuclear envelope|plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,regulation of gene expression|cell differentiation|positive regulation of bone mineralization|negative regulation of osteoblast proliferation|positive regulation of osteoblast differentiation|negative regulation of cyclin catabolic process|,molecular_function|,10,0.1,0.488,10,0,0,0.1,0.185,0.185,0.821,0,0,-1.6,1.3
ENSMUSG00000030201,LRP6,low density lipoprotein receptor-related protein 6,cell|early endosome|early endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|plasma membrane|caveola|caveola|cell surface|cell surface|membrane|integral component of membrane|cytoplasmic vesicle|neuronal cell body|neuronal cell body|receptor complex|synapse|synapse|,"gastrulation with mouth forming second|somitogenesis|neural tube closure|neural tube closure|negative regulation of protein phosphorylation|heart looping|morphogenesis of an epithelium|positive regulation of mesenchymal cell proliferation|pericardium morphogenesis|axis elongation|regulation of transcription, DNA-templated|negative regulation of protein kinase activity|endocytosis|receptor-mediated endocytosis|positive regulation of cytosolic calcium ion concentration|synaptic transmission|synaptic transmission|multicellular organismal development|embryonic pattern specification|dorsal/ventral axis specification|anterior/posterior pattern specification|anterior/posterior pattern specification|neural crest formation|neural crest formation|neural crest cell differentiation|Wnt signaling pathway|Wnt signaling pathway|single organismal cell-cell adhesion|cerebellum morphogenesis|thalamus development|cerebral cortex cell migration|forebrain radial glial cell differentiation|forebrain generation of neurons|Wnt signaling pathway involved in forebrain neuroblast division|Wnt signaling pathway involved in forebrain neuroblast division|neural tube development|formation of radial glial scaffolds|cerebral cortex development|negative regulation of Wnt signaling pathway|embryonic limb morphogenesis|forebrain development|midbrain development|midbrain-hindbrain boundary development|negative regulation of smooth muscle cell apoptotic process|limb morphogenesis|limb morphogenesis|embryonic forelimb morphogenesis|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic hindlimb morphogenesis|external genitalia morphogenesis|post-anal tail morphogenesis|post-anal tail morphogenesis|cell migration involved in gastrulation|regulation of cell proliferation|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|embryonic digit morphogenesis|positive regulation of apoptotic process|Wnt signaling pathway involved in dorsal/ventral axis specification|Wnt signaling pathway involved in dorsal/ventral axis specification|negative regulation of fat cell differentiation|positive regulation of ossification|positive regulation of bone resorption|positive regulation of cell cycle|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|bone remodeling|embryonic camera-type eye morphogenesis|generation of neurons|skeletal system morphogenesis|negative regulation of epithelial cell proliferation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|response to folic acid|palate development|convergent extension|retina morphogenesis in camera-type eye|embryonic retina morphogenesis in camera-type eye|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|regulation of cell development|face morphogenesis|bone morphogenesis|branching involved in mammary gland duct morphogenesis|trachea cartilage morphogenesis|mammary placode formation|mammary gland duct morphogenesis|canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|cellular response to cholesterol|dopaminergic neuron differentiation|negative regulation of protein serine/threonine kinase activity|primitive streak formation|receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|Wnt signaling pathway involved in somitogenesis|axis elongation involved in somitogenesis|positive regulation of canonical Wnt signaling pathway|toxin transport|toxin transport|negative regulation of non-canonical Wnt signaling pathway|positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification|negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis|negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis|negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis|negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis|negative regulation of planar cell polarity pathway involved in pericardium morphogenesis|negative regulation of planar cell polarity pathway involved in neural tube closure|",low-density lipoprotein receptor activity|low-density lipoprotein receptor activity|receptor binding|frizzled binding|protein binding|coreceptor activity|Wnt-protein binding|Wnt-protein binding|kinase inhibitor activity|toxin transporter activity|apolipoprotein binding|identical protein binding|protein homodimerization activity|Wnt-activated receptor activity|coreceptor activity involved in Wnt signaling pathway|,10,0,0,10,-0.4,0.902,-0.1,0.182,-0.182,0.822,0,0,-1.9,0.9
ENSMUSG00000022311,CSMD3,CUB and Sushi multiple domains 3,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.203,10,0.3,0.913,0.1,0.182,0.182,0.822,0,0,-1.1,1.7
ENSMUSG00000089669,TNFSF13,"tumor necrosis factor (ligand) superfamily, member 13",extracellular region|extracellular space|cytoplasm|external side of plasma membrane|membrane|extracellular vesicular exosome|,immune system process|immunoglobulin production in mucosal tissue|positive regulation of germinal center formation|immune response|positive regulation of cell proliferation|immunoglobulin mediated immune response|positive regulation of isotype switching to IgA isotypes|positive regulation of isotype switching to IgA isotypes|regulation of immune response|,cytokine activity|tumor necrosis factor receptor binding|,10,0.2,0.0927,10,-0.7,0.376,-0.1,0.181,-0.181,0.822,0,0,-1.9,0.9
ENSMUSG00000020674,PXDN,peroxidasin homolog (Drosophila),extracellular region|proteinaceous extracellular matrix|extracellular space|endoplasmic reticulum|extracellular matrix|extracellular matrix|,response to oxidative stress|extracellular matrix organization|extracellular matrix organization|hydrogen peroxide catabolic process|oxidation-reduction process|,peroxidase activity|extracellular matrix structural constituent|oxidoreductase activity|heme binding|metal ion binding|,10,0.1,0.233,10,-0.1,0.217,0.1,0.179,0.179,0.823,0,0,-1.3,1.6
ENSMUSG00000040112,MRPS35,mitochondrial ribosomal protein S35,cytoplasm|mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,poly(A) RNA binding|,10,-0.2,0.532,10,0,0,-0.1,0.179,-0.179,0.823,0,0,-1.6,1.2
ENSMUSG00000024193,PHF1,PHD finger protein 1,nucleus|cytoplasm|cytoskeleton|ESC/E(Z) complex|site of double-strand break|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|chromatin modification|negative regulation of histone H3-K27 methylation|positive regulation of histone H3-K27 methylation|",protein binding|zinc ion binding|methylated histone binding|methylated histone binding|metal ion binding|,10,0,0,10,-0.1,0.354,-0.1,0.175,-0.175,0.824,0,0,-1.9,1
ENSMUSG00000021983,ATP8A2,"ATPase, aminophospholipid transporter-like, class I, type 8A, member 2",endosome|Golgi apparatus|plasma membrane|membrane|integral component of membrane|cell projection|,involuntary skeletal muscle contraction|ATP catabolic process|transport|cation transport|lipid transport|axonogenesis|aging|positive regulation of neuron projection development|phospholipid transport|neuron projection development|positive regulation of multicellular organism growth|eating behavior|skin development|phospholipid translocation|neuron development|neuromuscular process controlling posture|neurofilament cytoskeleton organization|positive regulation of phospholipid translocation|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,0,0,10,0.2,0.739,0.1,0.173,0.173,0.824,0,0,-1.3,1.6
ENSMUSG00000020680,TAF15,"TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|cytoplasm|,biological_process|,poly(A) RNA binding|,10,-0.8,0.967,10,0,0,0.1,0.173,0.173,0.824,0,0,-2,1
ENSMUSG00000059003,GRIN2A,"glutamate receptor, ionotropic, NMDA2A (epsilon 1)",endoplasmic reticulum|plasma membrane|synaptic vesicle|cell surface|postsynaptic density|postsynaptic density|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|presynaptic membrane|presynaptic membrane|neuron projection|neuron projection|terminal bouton|dendritic spine|synapse|postsynaptic membrane|neuronal postsynaptic density|,"action potential|startle response|startle response|response to amphetamine|transport|ion transport|cation transport|calcium ion transport|calcium ion transport|synaptic transmission|synaptic transmission|learning or memory|learning|memory|memory|locomotory behavior|protein localization|protein localization|visual learning|response to wounding|response to wounding|positive regulation of cell death|sensory perception of pain|neurogenesis|sleep|directional locomotion|ion transmembrane transport|ion transmembrane transport|regulation of ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|locomotion|negative regulation of protein catabolic process|regulation of membrane potential|dopamine metabolic process|serotonin metabolic process|response to drug|positive regulation of apoptotic process|response to ethanol|response to ethanol|regulation of synaptic plasticity|regulation of long-term neuronal synaptic plasticity|rhythmic process|regulation of synaptic transmission|protein tetramerization|regulation of sensory perception of pain|regulation of postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|calcium ion transmembrane transport|cellular response to amino acid stimulus|cellular response to zinc ion|positive regulation of excitatory postsynaptic membrane potential|",receptor activity|ionotropic glutamate receptor activity|ionotropic glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|receptor binding|transporter activity|ion channel activity|extracellular-glutamate-gated ion channel activity|extracellular-glutamate-gated ion channel activity|cation channel activity|cation channel activity|calcium channel activity|calcium channel activity|protein binding|zinc ion binding|glutamate binding|protein kinase binding|voltage-gated cation channel activity|protein complex binding|glutamate receptor binding|neurotransmitter binding|metal ion binding|protein heterodimerization activity|protein dimerization activity|cell adhesion molecule binding|ATPase binding|scaffold protein binding|,10,0,0,10,0.2,0.811,0.1,0.172,0.172,0.824,0,0,-0.7,2
ENSMUSG00000060201,SPINK7,"serine peptidase inhibitor, Kazal type 7 (putative)",cellular_component|extracellular region|,biological_process|negative regulation of peptidase activity|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0.1,0.726,0.1,0.17,0.17,0.825,0,0,-1.2,1.7
ENSMUSG00000024598,FBN2,fibrillin 2,microfibril|extracellular region|extracellular region|proteinaceous extracellular matrix|,embryonic limb morphogenesis|positive regulation of bone mineralization|limb morphogenesis|sequestering of TGFbeta in extracellular matrix|positive regulation of osteoblast differentiation|bone trabecula formation|,extracellular matrix structural constituent|calcium ion binding|,10,0,0,10,-0.1,0.212,-0.1,0.167,-0.167,0.826,0,0,-1.7,1.2
ENSMUSG00000033900,MAP9,microtubule-associated protein 9,astral microtubule|cytoplasm|aster|cytoskeleton|microtubule|microtubule cytoskeleton|mitotic spindle|mitotic spindle midzone|,cytokinesis|cell cycle|mitotic nuclear division|regulation of mitosis|spindle assembly|cell division|spindle assembly involved in mitosis|,None,10,0.2,0.56,10,-0.1,0.213,0.1,0.164,0.164,0.827,0,0,-1.4,1.4
ENSMUSG00000038968,KLK1B16,kallikrein 1-related peptidase b16,nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.353,10,0,0,0.1,0.163,0.163,0.827,0,0,-1.1,1.8
ENSMUSG00000020893,PER1,period circadian clock 1,nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|regulation of sodium ion transport|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|circadian rhythm|circadian rhythm|posttranscriptional regulation of gene expression|circadian regulation of gene expression|circadian regulation of gene expression|circadian regulation of gene expression|regulation of hair cycle|regulation of circadian rhythm|negative regulation of I-kappaB kinase/NF-kappaB signaling|entrainment of circadian clock by photoperiod|histone H3 acetylation|histone H3 acetylation|histone H4 acetylation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of JNK cascade|rhythmic process|response to cAMP|histone H3 deacetylation|circadian regulation of translation|regulation of cytokine production involved in inflammatory response|regulation of p38MAPK cascade|negative regulation of glucocorticoid receptor signaling pathway|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|transcription factor binding transcription factor activity|signal transducer activity|protein binding|transcription factor binding|kinase binding|kinase binding|chromatin DNA binding|ubiquitin protein ligase binding|E-box binding|,10,0,0,10,0.1,0.332,0.1,0.163,0.163,0.827,0,0,-1.2,1.7
ENSMUSG00000023959,CLIC5,chloride intracellular channel 5,cytoplasm|Golgi apparatus|cytoskeleton|actin cytoskeleton|membrane|integral component of membrane|stereocilium|stereocilium bundle|chloride channel complex|extracellular vesicular exosome|,response to dietary excess|diet induced thermogenesis|transport|ion transport|chloride transport|sensory perception of sound|protein localization|regulation of ion transmembrane transport|neuromuscular process controlling balance|auditory receptor cell stereocilium organization|chloride transmembrane transport|,voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|,10,0.1,0.0373,10,0.1,0.14,0.1,0.162,0.162,0.827,0,0,-1.2,1.7
ENSMUSG00000034826,NUP54,nucleoporin 54,nucleus|nuclear pore|membrane|,protein targeting|transport|nucleocytoplasmic transport|protein transport|mRNA transport|,nucleocytoplasmic transporter activity|,10,-0.1,0.482,10,0.2,0.686,-0.1,0.159,-0.159,0.828,0,0,-1.5,1.4
ENSMUSG00000063730,HSD3B2,"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2",mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|endoplasmic reticulum|membrane|integral component of membrane|,steroid biosynthetic process|metabolic process|oxidation-reduction process|,"catalytic activity|3-beta-hydroxy-delta5-steroid dehydrogenase activity|steroid delta-isomerase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|isomerase activity|",10,0.2,0.995,10,-0.2,0.521,0.1,0.157,0.157,0.829,0,0,-1.6,1.2
ENSMUSG00000040254,SEMA3D,"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D",extracellular region|membrane|,multicellular organismal development|nervous system development|cell differentiation|,receptor activity|,10,0.4,0.775,10,-0.2,1.32,-0.1,0.154,-0.154,0.829,0,0,-1.2,1.7
ENSMUSG00000016382,PLS3,plastin 3 (T-isoform),cytoplasm|stereocilium|,bone development|,actin binding|calcium ion binding|metal ion binding|,10,0.3,1.56,10,0,0,0.2,0.151,0.151,0.83,0,0,-1.2,1.7
ENSMUSG00000025156,GPS1,G protein pathway suppressor 1,nucleus|cytoplasm|COP9 signalosome|COP9 signalosome|,cullin deneddylation|,protein binding|,10,0.2,0.878,10,0,0,0.1,0.151,0.151,0.83,0,0,-1.3,1.6
ENSMUSG00000001435,COL18A1,"collagen, type XVIII, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|basement membrane|extracellular space|extracellular matrix|extracellular vesicular exosome|,angiogenesis|angiogenesis|endothelial cell morphogenesis|cell adhesion|multicellular organismal development|positive regulation of cell proliferation|Wnt signaling pathway|extracellular matrix organization|positive regulation of cell migration|positive regulation of endothelial cell apoptotic process|,structural molecule activity|identical protein binding|metal ion binding|,9,-0.1,0.0972,9,-0.2,0.132,-0.1,0.149,-0.149,0.831,0,0,-1.8,1.2
ENSMUSG00000031372,TREX2,three prime repair exonuclease 2,nucleus|,"DNA catabolic process, exonucleolytic|DNA metabolic process|DNA repair|cellular response to DNA damage stimulus|",magnesium ion binding|nucleic acid binding|nuclease activity|exonuclease activity|3'-5'-exodeoxyribonuclease activity|exodeoxyribonuclease III activity|hydrolase activity|protein homodimerization activity|metal ion binding|,10,-0.2,0.799,10,0.7,0.451,-0.1,0.146,-0.146,0.831,0,0,-1.3,1.8
ENSMUSG00000019899,LAMA2,"laminin, alpha 2",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basal lamina|basal lamina|laminin-1 complex|sarcolemma|dendritic spine|extracellular vesicular exosome|,"cell adhesion|axon guidance|regulation of cell adhesion|regulation of cell migration|positive regulation of synaptic transmission, cholinergic|regulation of embryonic development|",receptor binding|,10,-0.2,0.235,10,0,0,-0.1,0.145,-0.145,0.832,0,0,-1.7,1.2
ENSMUSG00000025218,POLL,"polymerase (DNA directed), lambda",nucleus|,"DNA replication|DNA-dependent DNA replication|DNA repair|base-excision repair, gap-filling|nucleotide-excision repair|nucleotide-excision repair|cellular response to DNA damage stimulus|DNA biosynthetic process|",DNA binding|DNA-directed DNA polymerase activity|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|lyase activity|DNA polymerase activity|metal ion binding|,10,-0.1,0.432,10,0.3,1.26,-0.1,0.144,-0.144,0.832,0,0,-1.1,1.8
ENSMUSG00000031790,MMP15,matrix metallopeptidase 15,integral component of plasma membrane|membrane|integral component of membrane|extracellular matrix|,proteolysis|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.1,0.232,-0.1,0.142,-0.142,0.833,0,0,-1.2,1.8
ENSMUSG00000023249,PARP3,"poly (ADP-ribose) polymerase family, member 3",site of double-strand break|site of double-strand break|,telomere maintenance|double-strand break repair|double-strand break repair|protein ADP-ribosylation|positive regulation of DNA ligation|regulation of mitotic spindle organization|protein localization to site of double-strand break|,NAD+ ADP-ribosyltransferase activity|transferase activity|,10,0.3,1.06,10,0,0,0.2,0.141,0.141,0.833,0,0,-0.8,1.9
ENSMUSG00000047730,FCGBP,Fc fragment of IgG binding protein,proteinaceous extracellular matrix|extracellular vesicular exosome|,biological_process|,protein binding|,10,-0.1,0.0638,10,-0.1,0.0882,-0.1,0.138,-0.138,0.834,0,0,-1.2,1.8
ENSMUSG00000011382,DHDH,dihydrodiol dehydrogenase (dimeric),cellular_component|,metabolic process|D-xylose catabolic process|oxidation-reduction process|,"oxidoreductase activity|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity|D-xylose 1-dehydrogenase (NADP+) activity|",10,0,0,10,0.1,0.896,0.1,0.134,0.134,0.835,0,0,-1,1.9
ENSMUSG00000017652,CD40,CD40 antigen,extracellular region|extracellular space|cytoplasm|plasma membrane|plasma membrane|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|CD40 receptor complex|CD40 receptor complex|intracellular membrane-bounded organelle|extracellular vesicular exosome|,positive regulation of protein phosphorylation|immune system process|immune response-regulating cell surface receptor signaling pathway|cellular calcium ion homeostasis|cellular calcium ion homeostasis|inflammatory response|positive regulation of B cell proliferation|positive regulation of B cell proliferation|positive regulation of interleukin-12 production|positive regulation of Rac GTPase activity|B cell activation|positive regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of Cdc42 GTPase activity|positive regulation of MAP kinase activity|protein kinase B signaling|positive regulation of transcription from RNA polymerase II promoter|positive regulation of isotype switching to IgG isotypes|regulation of immune response|regulation of immunoglobulin secretion|positive regulation of NF-kappaB transcription factor activity|defense response to virus|positive regulation of protein kinase C signaling|positive regulation of endothelial cell apoptotic process|,antigen binding|protein binding|enzyme binding|ubiquitin protein ligase binding|,10,0.1,0.794,10,0,0,0.1,0.131,0.131,0.836,0,0,-1.9,1
ENSMUSG00000032418,ME1,"malic enzyme 1, NADP(+)-dependent, cytosolic",cytoplasm|mitochondrion|cytosol|,malate metabolic process|malate metabolic process|response to hormone|protein tetramerization|oxidation-reduction process|,malic enzyme activity|malic enzyme activity|malate dehydrogenase (decarboxylating) (NAD+) activity|malate dehydrogenase (decarboxylating) (NADP+) activity|malate dehydrogenase (decarboxylating) (NADP+) activity|malate dehydrogenase (decarboxylating) (NADP+) activity|malate dehydrogenase (decarboxylating) (NADP+) activity|protein binding|oxaloacetate decarboxylase activity|oxidoreductase activity|manganese ion binding|metal ion binding|NADP binding|NAD binding|,10,0,0,10,0.4,1.08,-0.1,0.13,-0.13,0.836,0,0,-1.3,1.5
ENSMUSG00000071723,GSPT2,G1 to S phase transition 2,cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|translation|cell cycle|",nucleotide binding|GTPase activity|GTP binding|poly(A) RNA binding|,10,0,0,10,-0.2,0.694,-0.1,0.128,-0.128,0.837,0,0,-1.5,1.4
ENSMUSG00000027164,TRAF6,TNF receptor-associated factor 6,intracellular|nucleus|nucleolus|cytoplasm|mitochondrion|lipid particle|cytosol|plasma membrane|cytoplasmic side of plasma membrane|CD40 receptor complex|protein complex|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|protein polyubiquitination|ossification|neural tube closure|immune system process|positive regulation of T cell cytokine production|protein complex assembly|immune response|signal transduction|signal transduction|I-kappaB kinase/NF-kappaB signaling|activation of NF-kappaB-inducing kinase activity|JNK cascade|organ morphogenesis|protein ubiquitination|protein ubiquitination|protein ubiquitination|cytokine-mediated signaling pathway|antigen processing and presentation of exogenous peptide antigen via MHC class II|osteoclast differentiation|positive regulation of lipopolysaccharide-mediated signaling pathway|activation of protein kinase activity|positive regulation of interleukin-2 production|T-helper 1 type immune response|positive regulation of T cell proliferation|odontogenesis of dentin-containing tooth|regulation of apoptotic process|myeloid dendritic cell differentiation|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of JUN kinase activity|positive regulation of interleukin-12 biosynthetic process|positive regulation of interleukin-6 biosynthetic process|bone resorption|positive regulation of osteoclast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|bone remodeling|cell development|positive regulation of smooth muscle cell proliferation|T cell receptor signaling pathway|regulation of immunoglobulin secretion|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein autoubiquitination|protein autoubiquitination|interleukin-1-mediated signaling pathway|interleukin-1-mediated signaling pathway|protein K63-linked ubiquitination|protein K63-linked ubiquitination|response to interleukin-1|cellular response to lipopolysaccharide|positive regulation of transcription regulatory region DNA binding|","ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|signal transducer activity|tumor necrosis factor receptor binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein kinase binding|mitogen-activated protein kinase kinase kinase binding|ubiquitin conjugating enzyme binding|ubiquitin protein ligase binding|thioesterase binding|histone deacetylase binding|protein kinase B binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein N-terminus binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,0.988,10,0.1,0.241,0.1,0.124,0.124,0.838,0,0,-1.9,0.9
ENSMUSG00000034690,NLRP4C,"NLR family, pyrin domain containing 4C",extracellular vesicular exosome|,inflammatory response|biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0.1,0.306,0.1,0.119,0.119,0.839,0,0,-1.1,1.8
ENSMUSG00000030077,CHL1,cell adhesion molecule with homology to L1CAM,extracellular region|proteinaceous extracellular matrix|plasma membrane|membrane|integral component of membrane|dendrite|apical part of cell|,neuron migration|cell adhesion|multicellular organismal development|nervous system development|axon guidance|adult locomotory behavior|cell differentiation|neuron projection development|exploration behavior|negative regulation of neuron apoptotic process|cognition|,protease binding|protein binding|,10,-0.1,0.382,10,0.2,1.07,0.1,0.117,0.117,0.84,0,0,-1.1,1.8
ENSMUSG00000037386,RIMS2,regulating synaptic membrane exocytosis 2,intracellular|cell|cell junction|neuron projection|protein complex|synapse|,transport|neurotransmitter transport|intracellular protein transport|exocytosis|calcium ion-dependent exocytosis|regulation of exocytosis|cAMP-mediated signaling|insulin secretion|insulin secretion|regulation of membrane potential|calcium ion-dependent exocytosis of neurotransmitter|regulation of synaptic vesicle exocytosis|,protein binding|Rab GTPase binding|protein domain specific binding|ion channel binding|metal ion binding|protein heterodimerization activity|,10,0.2,0.983,10,0,0,0.1,0.113,0.113,0.841,0,0,-1,1.8
ENSMUSG00000028654,MYCL,"v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)",nucleus|,"regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein dimerization activity|,10,0.4,1.57,10,0,0,0.1,0.112,0.112,0.841,0,0,-1,1.9
ENSMUSG00000030246,LDHB,lactate dehydrogenase B,cytoplasm|mitochondrion|membrane|extracellular vesicular exosome|,carbohydrate metabolic process|lactate metabolic process|glycolytic process|lactate biosynthetic process from pyruvate|NAD metabolic process|cellular carbohydrate metabolic process|oxidation-reduction process|,"catalytic activity|lactate dehydrogenase activity|L-lactate dehydrogenase activity|L-lactate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|kinase binding|identical protein binding|NAD binding|",10,0.1,0.0408,10,0.1,0.0819,0.1,0.112,0.112,0.841,0,0,-1.3,1.6
ENSMUSG00000005225,PLEKHA8,"pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8",cytoplasm|Golgi apparatus|trans-Golgi network|membrane|,transport|lipid transport|ER to Golgi ceramide transport|glycolipid transport|,lipid binding|glycolipid transporter activity|glycolipid binding|phosphatidylinositol-4-phosphate binding|ceramide binding|,10,-0.1,0.0502,10,0.2,0.3,0.1,0.112,0.112,0.841,0,0,-1.4,1.5
ENSMUSG00000049612,OMG,oligodendrocyte myelin glycoprotein,plasma membrane|membrane|anchored component of membrane|myelin sheath|,cell adhesion|central nervous system myelination|neuron projection regeneration|regulation of collateral sprouting of intact axon in response to injury|,identical protein binding|protein homodimerization activity|,10,0,0,10,0.9,0.993,0.1,0.111,0.111,0.842,0,0,-0.9,2
ENSMUSG00000031432,PRPS1,phosphoribosyl pyrophosphate synthetase 1,ribose phosphate diphosphokinase complex|protein complex|,5-phosphoribose 1-diphosphate biosynthetic process|purine nucleobase metabolic process|purine nucleotide biosynthetic process|AMP biosynthetic process|nervous system development|ribonucleoside monophosphate biosynthetic process|nucleotide biosynthetic process|phosphorylation|ribose phosphate metabolic process|urate biosynthetic process|cellular biosynthetic process|hypoxanthine biosynthetic process|,nucleotide binding|magnesium ion binding|ribose phosphate diphosphokinase activity|ATP binding|AMP binding|kinase activity|transferase activity|GDP binding|carbohydrate binding|protein homodimerization activity|ADP binding|metal ion binding|,10,-0.4,1.41,10,0,0,0.1,0.111,0.111,0.842,0,0,-1.8,1
ENSMUSG00000019971,CEP290,centrosomal protein 290,gamma-tubulin complex|nucleus|cytoplasm|centrosome|centrosome|cytosol|cytoskeleton|cilium|membrane|photoreceptor connecting cilium|centriolar satellite|centriolar satellite|TCTN-B9D complex|ciliary basal body|cell projection|protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|establishment or maintenance of cell polarity|protein transport|cell projection organization|regulation of cAMP metabolic process|cilium assembly|positive regulation of transcription, DNA-templated|retina development in camera-type eye|cilium morphogenesis|regulation of establishment of protein localization|positive regulation of intracellular protein transport|",protein binding|,10,-0.7,1.42,10,-0.1,0.212,-0.1,0.109,-0.109,0.842,0,0,-1.9,0.8
ENSMUSG00000029131,DNAJB6,"DnaJ (Hsp40) homolog, subfamily B, member 6",nucleus|nucleus|cytoplasm|cytoplasm|cytosol|membrane|Z disc|perinuclear region of cytoplasm|,"protein folding|actin cytoskeleton organization|extracellular matrix organization|positive regulation of ATPase activity|protein localization to nucleus|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|intermediate filament organization|negative regulation of transcription, DNA-templated|chorio-allantoic fusion|syncytiotrophoblast cell differentiation involved in labyrinthine layer development|chorion development|chaperone-mediated protein folding|negative regulation of inclusion body assembly|",ATPase activator activity|DNA binding|protein binding|heat shock protein binding|protein binding involved in protein folding|unfolded protein binding|chaperone binding|,10,-0.1,0.33,10,0.2,0.393,-0.1,0.108,-0.108,0.842,0,0,-1.6,1.2
ENSMUSG00000036822,TOPORS,"topoisomerase I binding, arginine/serine-rich",ubiquitin ligase complex|spindle pole|gamma-tubulin complex|nucleus|nucleus|centriole|PML body|PML body|nuclear speck|photoreceptor connecting cilium|photoreceptor connecting cilium|ciliary basal body|ciliary basal body|,"ubiquitin-dependent protein catabolic process|protein monoubiquitination|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|intrinsic apoptotic signaling pathway in response to DNA damage|protein sumoylation|protein localization to nucleus|regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of transcription, DNA-templated|positive regulation of ubiquitin-protein transferase activity|maintenance of protein location in nucleus|protein K48-linked ubiquitination|","DNA binding|antigen binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|DNA topoisomerase binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.1,0.369,-0.1,0.104,-0.104,0.843,0,0,-1,2
ENSMUSG00000059409,PPP2R5D,"protein phosphatase 2, regulatory subunit B', delta",None,regulation of protein phosphorylation|positive regulation of neuron projection development|regulation of protein autophosphorylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of neurotrophin TRK receptor signaling pathway|cellular response to growth factor stimulus|,protein binding|,10,0.1,0.111,10,0.9,0.305,0.1,0.103,0.103,0.844,0,0,-0.7,2
ENSMUSG00000020063,SIRT1,sirtuin 1,chromatin|nuclear chromatin|nucleus|nucleus|nuclear envelope|nuclear inner membrane|nucleoplasm|chromatin silencing complex|nuclear euchromatin|nuclear heterochromatin|nuclear heterochromatin|cytoplasm|mitochondrion|PML body|rDNA heterochromatin|ESC/E(Z) complex|,"single strand break repair|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|chromatin silencing at rDNA|pyrimidine dimer repair by nucleotide-excision repair|pyrimidine dimer repair by nucleotide-excision repair|DNA synthesis involved in DNA repair|angiogenesis|ovulation from ovarian follicle|cellular glucose homeostasis|positive regulation of protein phosphorylation|positive regulation of adaptive immune response|chromatin organization|establishment of chromatin silencing|maintenance of chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|protein deacetylation|protein deacetylation|protein deacetylation|triglyceride mobilization|apoptotic process|cellular response to DNA damage stimulus|response to oxidative stress|multicellular organismal development|spermatogenesis|regulation of mitotic cell cycle|muscle organ development|positive regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage|cellular response to starvation|positive regulation of cholesterol efflux|regulation of glucose metabolic process|positive regulation of macroautophagy|positive regulation of macroautophagy|protein ubiquitination|histone deacetylation|histone deacetylation|histone deacetylation|histone deacetylation|peptidyl-lysine acetylation|cell differentiation|negative regulation of cell growth|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of prostaglandin biosynthetic process|protein destabilization|positive regulation of chromatin silencing|negative regulation of TOR signaling|negative regulation of TOR signaling|regulation of endodeoxyribonuclease activity|negative regulation of NF-kappaB transcription factor activity|response to insulin|regulation of protein import into nucleus, translocation|regulation of smooth muscle cell apoptotic process|peptidyl-lysine deacetylation|cellular triglyceride homeostasis|regulation of peroxisome proliferator activated receptor signaling pathway|regulation of cell proliferation|negative regulation of phosphorylation|negative regulation of phosphorylation|response to hydrogen peroxide|behavioral response to starvation|cholesterol homeostasis|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of MHC class II biosynthetic process|negative regulation of fat cell differentiation|positive regulation of DNA repair|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of insulin receptor signaling pathway|white fat cell differentiation|negative regulation of helicase activity|positive regulation of histone H3-K9 methylation|negative regulation of protein kinase B signaling|negative regulation of protein kinase B signaling|fatty acid homeostasis|negative regulation of androgen receptor signaling pathway|cellular response to hydrogen peroxide|regulation of bile acid biosynthetic process|histone H3 deacetylation|histone H3 deacetylation|cellular response to tumor necrosis factor|cellular response to hypoxia|cellular response to ionizing radiation|negative regulation of neuron death|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|positive regulation of macrophage apoptotic process|negative regulation of cAMP-dependent protein kinase activity|positive regulation of cAMP-dependent protein kinase activity|positive regulation of cAMP-dependent protein kinase activity|negative regulation of cellular response to testosterone stimulus|negative regulation of peptidyl-lysine acetylation|negative regulation of cellular senescence|positive regulation of cellular senescence|regulation of RNA biosynthetic process|","p53 binding|p53 binding|transcription corepressor activity|transcription corepressor activity|histone deacetylase activity|protein binding|protein C-terminus binding|transcription factor binding|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|NAD-dependent histone deacetylase activity|NAD-dependent histone deacetylase activity|NAD-dependent histone deacetylase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|deacetylase activity|deacetylase activity|enzyme binding|enzyme binding|protein domain specific binding|protein deacetylase activity|protein deacetylase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|NAD-dependent protein deacetylase activity|NAD-dependent protein deacetylase activity|histone binding|identical protein binding|HLH domain binding|bHLH transcription factor binding|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|N-acetylgalactosamine-6-phosphate deacetylase activity|mitogen-activated protein kinase binding|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|NAD+ binding|keratin filament binding|",10,-0.1,0.257,10,0,0,-0.1,0.101,-0.101,0.844,0,0,-1.7,1.3
ENSMUSG00000032494,TDGF1,teratocarcinoma-derived growth factor 1,extracellular region|extracellular space|extracellular space|nucleus|cytoplasm|Golgi apparatus|plasma membrane|cell surface|cell surface|membrane|apical plasma membrane|extrinsic component of plasma membrane|anchored component of membrane|membrane raft|perinuclear region of cytoplasm|,"activation of MAPK activity|vasculogenesis|in utero embryonic development|morphogenesis of a branching structure|positive regulation of cell-matrix adhesion|cell migration involved in sprouting angiogenesis|gastrulation|heart development|heart development|positive regulation of cell proliferation|anterior/posterior axis specification, embryo|anterior/posterior axis specification|regulation of signal transduction|regulation of signal transduction|positive regulation of endothelial cell migration|peptidyl-serine phosphorylation|cell differentiation|regulation of cell migration|positive regulation of cell migration|positive regulation of cell migration|BMP signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|cellular response to hepatocyte growth factor stimulus|nodal signaling pathway|nodal signaling pathway|negative regulation of apoptotic process|cellular response to fibroblast growth factor stimulus|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fibroblast proliferation|positive regulation of peptidyl-tyrosine phosphorylation|cardiac muscle cell differentiation|canonical Wnt signaling pathway|cellular response to interferon-gamma|cellular response to interleukin-6|cellular response to tumor necrosis factor|cellular response to epidermal growth factor stimulus|",receptor binding|protein binding|growth factor activity|coreceptor activity|Wnt-protein binding|nodal binding|type I activin receptor binding|,10,0.1,0.18,10,0,0,0.1,0.101,0.101,0.844,0,0,-1.2,1.7
ENSMUSG00000045083,LINGO2,leucine rich repeat and Ig domain containing 2,membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.112,10,0,0,-0.1,0.0985,-0.0985,0.845,0,0,-1.8,1.1
ENSMUSG00000029167,PPARGC1A,"peroxisome proliferative activated receptor, gamma, coactivator 1 alpha",nucleus|nucleus|cytosol|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mitochondrion organization|positive regulation of mitochondrion organization|regulation of cell death|response to muscle activity|negative regulation of smooth muscle cell migration|respiratory electron transport chain|positive regulation of cellular metabolic process|circadian regulation of gene expression|cellular response to oxidative stress|regulation of circadian rhythm|negative regulation of neuron apoptotic process|negative regulation of glycolytic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fatty acid oxidation|rhythmic process|positive regulation of smooth muscle cell proliferation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|neuron death|positive regulation of cellular respiration|positive regulation of mitochondrial DNA metabolic process|positive regulation of muscle tissue development|negative regulation of receptor activity|regulation of N-methyl-D-aspartate selective glutamate receptor activity|positive regulation of energy homeostasis|positive regulation of ATP biosynthetic process|",nucleotide binding|nucleic acid binding|DNA binding|chromatin binding|transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|RNA binding|protein binding|transcription factor binding|ligand-dependent nuclear receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|chromatin DNA binding|sequence-specific DNA binding|,10,0,0,10,0.3,0.434,0.1,0.0965,0.0965,0.846,0,0,-1.2,1.7
ENSMUSG00000043631,ECM2,"extracellular matrix protein 2, female organ and adipocyte specific",extracellular region|proteinaceous extracellular matrix|interstitial matrix|extracellular matrix|,positive regulation of cell-substrate adhesion|extracellular matrix organization|,collagen binding|heparin binding|collagen V binding|,10,0,0,10,0.1,0.792,0.1,0.0953,0.0953,0.846,0,0,-1.4,1.6
ENSMUSG00000051592,CCNB3,cyclin B3,nucleus|,regulation of cyclin-dependent protein serine/threonine kinase activity|cell cycle|meiotic nuclear division|biological_process|regulation of G2/M transition of mitotic cell cycle|cell division|,molecular_function|protein kinase binding|,10,-0.2,0.185,10,0.4,1.11,0.1,0.0896,0.0896,0.847,0,0,-1.4,1.5
ENSMUSG00000031385,PLXNB3,plexin B3,intracellular|plasma membrane|membrane|integral component of membrane|,positive regulation of endothelial cell proliferation|negative regulation of cell adhesion|signal transduction|multicellular organismal development|nervous system development|negative regulation of lamellipodium assembly|negative regulation of cell migration|negative regulation of GTPase activity|positive chemotaxis|cell chemotaxis|semaphorin-plexin signaling pathway|,receptor activity|protein binding|semaphorin receptor activity|protein domain specific binding|Rho GDP-dissociation inhibitor binding|,10,-0.2,0.464,10,0,0,-0.1,0.0896,-0.0896,0.847,0,0,-1.1,1.9
ENSMUSG00000062825,ACTG1,"actin, gamma, cytoplasmic 1",extracellular space|nucleus|cytoplasm|cytoskeleton|actin cytoskeleton|membrane|myofibril|filamentous actin|costamere|extracellular vesicular exosome|blood microparticle|,sarcomere organization|,nucleotide binding|structural constituent of cytoskeleton|protein binding|ATP binding|identical protein binding|,10,0,0,10,0.1,0.422,0.1,0.0889,0.0889,0.848,0,0,-1.4,1.6
ENSMUSG00000016206,H2-M3,"histocompatibility 2, M region locus 3",external side of plasma membrane|membrane|MHC class Ib protein complex|,"positive regulation of T cell mediated cytotoxicity|positive regulation of T cell mediated cytotoxicity|response to molecule of bacterial origin|alpha-beta T cell activation involved in immune response|antigen processing and presentation of endogenous peptide antigen via MHC class Ib|antigen processing and presentation of exogenous peptide antigen via MHC class Ib|antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent|positive regulation of T cell tolerance induction|immune response-inhibiting cell surface receptor signaling pathway|positive regulation of interferon-gamma production|positive regulation of interleukin-12 production|negative regulation of T cell proliferation|defense response to bacterium|defense response to bacterium|positive regulation of nitric oxide biosynthetic process|positive regulation of regulatory T cell differentiation|positive regulation of natural killer cell mediated cytotoxicity|negative regulation of dendritic cell differentiation|",receptor binding|peptide antigen binding|peptide antigen binding|,10,-0.4,1.52,10,0,0,-0.2,0.0879,-0.0879,0.848,0,0,-1.9,0.8
ENSMUSG00000031201,BRCC3,"BRCA1/BRCA2-containing complex, subunit 3",ubiquitin ligase complex|nuclear ubiquitin ligase complex|nucleus|BRCA1-A complex|BRISC complex|,DNA repair|double-strand break repair|proteolysis|cellular response to DNA damage stimulus|response to X-ray|response to ionizing radiation|chromatin modification|G2 DNA damage checkpoint|positive regulation of DNA repair|regulation of catalytic activity|protein K63-linked deubiquitination|histone H2A K63-linked deubiquitination|,ubiquitin thiolesterase activity|ubiquitin-specific protease activity|protein binding|peptidase activity|metallopeptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|enzyme regulator activity|polyubiquitin binding|metal ion binding|,10,-0.1,0.0385,10,0.2,0.17,-0.1,0.0869,-0.0869,0.848,0,0,-1.4,1.5
ENSMUSG00000047514,TSPYL1,"testis-specific protein, Y-encoded-like 1",nucleus|,nucleosome assembly|,enzyme binding|,10,0,0,10,0.1,0.288,0.1,0.0865,0.0865,0.848,0,0,-1.4,1.6
ENSMUSG00000069769,MSI2,musashi RNA-binding protein 2,cytoplasm|polysome|,stem cell development|,nucleotide binding|nucleic acid binding|RNA binding|single-stranded RNA binding|poly(U) RNA binding|poly(A) RNA binding|,10,-0.4,1.22,10,0.1,0.193,-0.1,0.0851,-0.0851,0.849,0,0,-1.4,1.6
ENSMUSG00000026420,IL24,interleukin 24,extracellular region|extracellular space|endoplasmic reticulum|,apoptotic process|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell migration|serine phosphorylation of STAT3 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|,cytokine activity|protein binding|,10,0.5,0.938,10,-0.2,0.666,-0.1,0.0794,-0.0794,0.85,0,0,-1.2,1.7
ENSMUSG00000021919,CHAT,choline acetyltransferase,mitochondrion|axon|neuron projection|neuron projection|neuronal cell body|,synaptic transmission|neuromuscular synaptic transmission|muscle organ development|establishment of synaptic specificity at neuromuscular junction|memory|rhythmic behavior|adult walking behavior|acetylcholine biosynthetic process|dendrite development|neuron differentiation|neurotransmitter biosynthetic process|rhythmic excitation|,"choline O-acetyltransferase activity|choline O-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|choline binding|",10,-0.5,0.313,10,0.1,0.535,0.1,0.0775,0.0775,0.851,0,0,-1.9,1.1
ENSMUSG00000028938,GALNTL5,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5,endosome|membrane|integral component of membrane|,spermatogenesis|spermatid development|spermatid development|cell differentiation|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0,0,10,0.1,0.283,0.1,0.0749,0.0749,0.851,0,0,-1.2,1.7
ENSMUSG00000029361,NOS1,"nitric oxide synthase 1, neuronal",photoreceptor inner segment|nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|cytosol|cytosol|cytoskeleton|plasma membrane|vesicle membrane|postsynaptic density|membrane|sarcoplasmic reticulum|dendrite|nuclear membrane|sarcolemma|sarcolemma|azurophil granule|cell projection|protein complex|membrane raft|synapse|synapse|perinuclear region of cytoplasm|,"regulation of sodium ion transport|arginine catabolic process|nitric oxide biosynthetic process|nitric oxide biosynthetic process|striated muscle contraction|nitric oxide mediated signal transduction|regulation of heart contraction|negative regulation of cell proliferation|response to heat|peptidyl-cysteine S-nitrosylation|peptidyl-cysteine S-nitrosylation|positive regulation of guanylate cyclase activity|multicellular organismal response to stress|positive regulation of histone acetylation|exogenous drug catabolic process|negative regulation of apoptotic process|negative regulation of potassium ion transport|response to peptide hormone|response to estrogen|negative regulation of blood pressure|negative regulation of blood pressure|negative regulation of heart contraction|positive regulation of transcription, DNA-templated|negative regulation of vasoconstriction|positive regulation of vasodilation|positive regulation of vasodilation|positive regulation of transcription from RNA polymerase II promoter|negative regulation of insulin secretion|behavioral response to cocaine|negative regulation of hydrolase activity|negative regulation of cytosolic calcium ion concentration|negative regulation of serotonin uptake|negative regulation of calcium ion transport|regulation of sensory perception of pain|oxidation-reduction process|cellular response to mechanical stimulus|cellular response to growth factor stimulus|positive regulation of long-term synaptic potentiation|positive regulation of neuron death|positive regulation of sodium ion transmembrane transport|",NADPH-hemoprotein reductase activity|nitric-oxide synthase activity|nitric-oxide synthase activity|iron ion binding|protein binding|calmodulin binding|FMN binding|oxidoreductase activity|sodium channel regulator activity|enzyme binding|heme binding|protein homodimerization activity|ion channel binding|cadmium ion binding|metal ion binding|flavin adenine dinucleotide binding|NADP binding|scaffold protein binding|,10,-0.2,0.219,10,0,0,-0.1,0.068,-0.068,0.853,0,0,-1.7,1.1
ENSMUSG00000039994,TIMELESS,timeless circadian clock 1,nuclear chromatin|nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|branching involved in ureteric bud morphogenesis|kidney development|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|multicellular organismal development|embryo development|lung development|regulation of circadian rhythm|positive regulation of circadian rhythm|cell cycle phase transition|negative regulation of transcription, DNA-templated|rhythmic process|branching morphogenesis of an epithelial tube|cell division|",protein binding|protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,0.2,0.875,0.1,0.0659,0.0659,0.854,0,0,-1.4,1.5
ENSMUSG00000073542,CEP76,centrosomal protein 76,cytoplasm|centrosome|centriole|cytoskeleton|protein complex|,regulation of centriole replication|,molecular_function|,10,-0.3,1.35,10,0.1,0.0111,-0.1,0.065,-0.065,0.854,0,0,-1.5,1.3
ENSMUSG00000031077,FADD,Fas (TNFRSF6)-associated via death domain,cytoplasm|cytosol|death-inducing signaling complex|CD95 death-inducing signaling complex|neuron projection|protein complex|cell body|membrane raft|ripoptosome|,"positive regulation of T cell mediated cytotoxicity|immune system process|positive regulation of adaptive immune response|apoptotic process|signal transduction|T cell differentiation|positive regulation of interferon-gamma production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|T cell differentiation in thymus|TRAIL-activated apoptotic signaling pathway|positive regulation of activated T cell proliferation|regulation of apoptotic process|T cell homeostasis|positive regulation of apoptotic process|innate immune response|positive regulation of macrophage differentiation|positive regulation of proteolysis|positive regulation of transcription from RNA polymerase II promoter|lymph node development|spleen development|thymus development|cardiac muscle tissue development|protein heterooligomerization|defense response to virus|positive regulation of type I interferon-mediated signaling pathway|negative regulation of necroptotic process|negative regulation of activation-induced cell death of T cells|motor neuron apoptotic process|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|activation of cysteine-type endopeptidase activity|necroptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation|positive regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|",protease binding|death receptor binding|tumor necrosis factor receptor binding|protein binding|protein complex binding|tumor necrosis factor receptor superfamily binding|death effector domain binding|identical protein binding|,8,-0.6,0.871,9,0.9,0.244,0.1,0.0631,0.0631,0.854,0,0,-1.6,1.7
ENSMUSG00000019997,CTGF,connective tissue growth factor,extracellular region|proteinaceous extracellular matrix|extracellular space|Golgi apparatus|cis-Golgi network|cytosol|cell cortex|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,cartilage condensation|ossification|angiogenesis|angiogenesis|regulation of cell growth|tissue homeostasis|positive regulation of protein phosphorylation|DNA replication|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|positive regulation of gene expression|negative regulation of gene expression|positive regulation of cell death|cell migration|cell differentiation|lung development|regulation of chondrocyte differentiation|positive regulation of collagen biosynthetic process|intracellular signal transduction|chondrocyte proliferation|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of cell differentiation|positive regulation of JNK cascade|positive regulation of cell activation|positive regulation of stress fiber assembly|cytosolic calcium ion transport|positive regulation of cardiac muscle contraction|negative regulation of cell death|connective tissue development|extracellular matrix constituent secretion|positive regulation of G0 to G1 transition|positive regulation of ERK1 and ERK2 cascade|reactive oxygen species metabolic process|,fibronectin binding|integrin binding|insulin-like growth factor binding|growth factor activity|heparin binding|,10,0.1,0.157,10,-0.2,1.15,-0.1,0.0593,-0.0593,0.855,0,0,-1.5,1.3
ENSMUSG00000020891,ALOX8,arachidonate 8-lipoxygenase,intracellular|cytoplasm|cytosol|cytoskeleton|plasma membrane|membrane|extrinsic component of membrane|,lipid metabolic process|negative regulation of cell proliferation|positive regulation of macrophage derived foam cell differentiation|arachidonic acid metabolic process|arachidonic acid metabolic process|lipoxygenase pathway|lipoxygenase pathway|positive regulation of peroxisome proliferator activated receptor signaling pathway|linoleic acid metabolic process|positive regulation of keratinocyte differentiation|negative regulation of cell cycle|negative regulation of growth|hepoxilin biosynthetic process|oxidation-reduction process|positive regulation of chemokine secretion|,"iron ion binding|calcium ion binding|lipid binding|linoleate 13S-lipoxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|2,3-dihydroxy DDT 1,2-dioxygenase activity|phenanthrene dioxygenase activity|2,2',3-trihydroxybiphenyl dioxygenase activity|1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity|5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity|1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity|protocatechuate 3,4-dioxygenase type II activity|2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity|3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity|2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity|carbazole 1,9a-dioxygenase activity|dihydroxydibenzothiophene dioxygenase activity|1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity|styrene dioxygenase activity|3,4-dihydroxyphenanthrene dioxygenase activity|hydroquinone 1,2-dioxygenase activity|p-cumate 2,3-dioxygenase activity|2,3-dihydroxy-p-cumate dioxygenase activity|3,5-dichlorocatechol 1,2-dioxygenase activity|2-aminophenol 1,6-dioxygenase activity|2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity|chlorocatechol 1,2-dioxygenase activity|catechol dioxygenase activity|dihydroxyfluorene dioxygenase activity|5-aminosalicylate dioxygenase activity|3-hydroxy-2-naphthoate 2,3-dioxygenase activity|benzo(a)pyrene 11,12-dioxygenase activity|benzo(a)pyrene 4,5-dioxygenase activity|4,5-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 9,10-dioxygenase activity|9,10-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 7,8-dioxygenase activity|7,8-dihydroxy benzo(a)pyrene dioxygenase activity|1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity|2-mercaptobenzothiazole dioxygenase activity|pyridine-3,4-diol dioxygenase activity|pyrene dioxygenase activity|4,5-dihydroxypyrene dioxygenase activity|phenanthrene-4-carboxylate dioxygenase activity|tetrachlorobenzene dioxygenase activity|4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity|2,3-dihydroxydiphenyl ether dioxygenase activity|diphenyl ether 1,2-dioxygenase activity|arachidonate 8(S)-lipoxygenase activity|metal ion binding|4-hydroxycatechol 1,2-dioxygenase activity|arachidonate 8(R)-lipoxygenase activity|arachidonate 15-lipoxygenase activity|dioxygenase activity|",10,0,0,10,0.4,1.11,0.1,0.0589,0.0589,0.855,0,0,-0.8,1.9
ENSMUSG00000073491,PYDC4,pyrin domain containing 4,nucleus|nucleolus|cytoplasm|membrane|,biological_process|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,10,0,0,10,0.4,1.14,0.1,0.0555,0.0555,0.856,0,0,-1,1.8
ENSMUSG00000046049,RP1L1,retinitis pigmentosa 1 homolog (human)-like 1,photoreceptor outer segment|cytoplasm|cytoskeleton|cilium|axoneme|photoreceptor connecting cilium|cell projection|extracellular vesicular exosome|,visual perception|cell projection organization|intracellular signal transduction|photoreceptor cell development|photoreceptor cell maintenance|photoreceptor cell maintenance|response to stimulus|,molecular_function|,10,0.5,1.12,10,0,0,0.1,0.054,0.054,0.857,0,0,-0.8,2
ENSMUSG00000030724,CD19,CD19 antigen,external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,B cell receptor signaling pathway|positive regulation of release of sequestered calcium ion into cytosol|,None,10,0,0,10,0.2,0.362,0.1,0.0536,0.0536,0.857,0,0,-1.4,1.5
ENSMUSG00000041219,ARHGAP11A,Rho GTPase activating protein 11A,intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,0,0,10,0.2,0.269,0.1,0.0533,0.0533,0.857,0,0,-1.3,1.6
ENSMUSG00000025658,CNKSR2,connector enhancer of kinase suppressor of Ras 2,cytoplasm|Golgi apparatus|plasma membrane|membrane|neuron projection|neuronal cell body|postsynaptic membrane|extracellular vesicular exosome|,regulation of signal transduction|intracellular signal transduction|,protein kinase binding|identical protein binding|,9,0.3,0.986,10,-0.2,0.522,-0.1,0.0517,-0.0517,0.857,0,0,-1.3,1.6
ENSMUSG00000055320,TEAD1,TEA domain family member 1,intracellular|nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|Golgi apparatus|,"embryonic heart tube morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|notochord development|hippo signaling|hippo signaling|regulation of cell proliferation|positive regulation of transcription from RNA polymerase II promoter|paraxial mesoderm development|lateral mesoderm development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|,10,0.2,0.179,10,-0.1,0.057,-0.1,0.0515,-0.0515,0.857,0,0,-1.3,1.6
ENSMUSG00000020307,CDC34,cell division cycle 34,nucleus|cytoplasm|,protein polyubiquitination|cell cycle|protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of neuron apoptotic process|negative regulation of cAMP-mediated signaling|protein K48-linked ubiquitination|positive regulation of inclusion body assembly|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0.6,0.262,10,-0.2,0.403,0.1,0.0501,0.0501,0.858,0,0,-1,1.9
ENSMUSG00000002603,TGFB1,"transforming growth factor, beta 1",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|nucleus|cytoplasm|microvillus|cell surface|secretory granule|axon|extracellular matrix|neuronal cell body|blood microparticle|,"protein import into nucleus, translocation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|skeletal system development|morphogenesis of a branching structure|cell activation|epithelial to mesenchymal transition|negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|regulation of sodium ion transport|chondrocyte differentiation|hematopoietic progenitor cell differentiation|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains|tolerance induction to self antigen|protein phosphorylation|protein phosphorylation|protein export from nucleus|ATP biosynthetic process|phosphate-containing compound metabolic process|cellular calcium ion homeostasis|defense response|inflammatory response|inflammatory response|cell cycle arrest|mitotic cell cycle checkpoint|epidermal growth factor receptor signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|common-partner SMAD protein phosphorylation|SMAD protein complex assembly|SMAD protein import into nucleus|negative regulation of neuroblast proliferation|endoderm development|skeletal muscle tissue development|negative regulation of DNA replication|cell proliferation|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|germ cell migration|defense response to fungus, incompatible interaction|organ morphogenesis|response to organic substance|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|positive regulation of fibroblast migration|positive regulation of peptidyl-threonine phosphorylation|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of macrophage cytokine production|cell growth|regulation of striated muscle tissue development|regulation of transforming growth factor beta receptor signaling pathway|evasion or tolerance of host defenses by virus|negative regulation of cell-cell adhesion|hyaluronan catabolic process|T cell differentiation|negative regulation of ossification|negative regulation of cell growth|negative regulation of cell growth|positive regulation of cell migration|mammary gland development|positive regulation of histone deacetylation|organ regeneration|positive regulation of protein complex assembly|positive regulation of exit from mitosis|lipopolysaccharide-mediated signaling pathway|positive regulation of cellular protein metabolic process|response to estradiol|response to progesterone|positive regulation of interleukin-17 production|positive regulation of interleukin-17 production|receptor catabolic process|positive regulation of superoxide anion generation|mononuclear cell proliferation|positive regulation of collagen biosynthetic process|positive regulation of collagen biosynthetic process|positive regulation of peptidyl-serine phosphorylation|positive regulation of histone acetylation|positive regulation of protein dephosphorylation|growth|wound healing|T cell activation|T cell activation|regulation of cell proliferation|negative regulation of T cell proliferation|regulation of protein import into nucleus|positive regulation of protein import into nucleus|positive regulation of odontogenesis|myelination|myeloid dendritic cell differentiation|T cell homeostasis|positive regulation of apoptotic process|positive regulation of MAP kinase activity|protein kinase B signaling|positive regulation of blood vessel endothelial cell migration|negative regulation of blood vessel endothelial cell migration|positive regulation of phosphatidylinositol 3-kinase activity|regulatory T cell differentiation|regulatory T cell differentiation|cell-cell junction organization|negative regulation of fat cell differentiation|negative regulation of myoblast differentiation|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of isotype switching to IgA isotypes|lymph node development|negative regulation of skeletal muscle tissue development|positive regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|positive regulation of protein secretion|negative regulation of phagocytosis|negative regulation of immune response|negative regulation of T cell activation|positive regulation of chemotaxis|positive regulation of NF-kappaB transcription factor activity|regulation of binding|regulation of DNA binding|positive regulation of smooth muscle cell differentiation|negative regulation of release of sequestered calcium ion into cytosol|positive regulation of cell division|positive regulation of protein kinase B signaling|pathway-restricted SMAD protein phosphorylation|pathway-restricted SMAD protein phosphorylation|positive regulation of SMAD protein import into nucleus|mammary gland branching involved in thelarche|branch elongation involved in mammary gland duct branching|regulation of branching involved in mammary gland duct morphogenesis|regulation of cartilage development|lens fiber cell differentiation|response to cholesterol|positive regulation of cell cycle arrest|cellular response to growth factor stimulus|cellular response to organic cyclic compound|cellular response to dexamethasone stimulus|cellular response to transforming growth factor beta stimulus|cellular response to transforming growth factor beta stimulus|extracellular matrix assembly|extracellular matrix assembly|positive regulation of branching involved in ureteric bud morphogenesis|extrinsic apoptotic signaling pathway|negative regulation of hyaluronan biosynthetic process|positive regulation of protein localization to nucleus|positive regulation of NAD+ ADP-ribosyltransferase activity|regulation of actin cytoskeleton reorganization|regulation of miRNA metabolic process|positive regulation of transcription regulatory region DNA binding|",glycoprotein binding|antigen binding|type II transforming growth factor beta receptor binding|transforming growth factor beta receptor binding|transforming growth factor beta receptor binding|protein binding|growth factor activity|enzyme binding|protein homodimerization activity|protein heterodimerization activity|protein N-terminus binding|,10,-0.1,0.204,10,0,0,-0.1,0.0498,-0.0498,0.858,0,0,-1.5,1.4
ENSMUSG00000022178,AJUBA,ajuba LIM protein,cytoplasmic mRNA processing body|nucleus|nucleus|transcription factor complex|cytoplasm|cytosol|cytoskeleton|plasma membrane|cell-cell junction|focal adhesion|membrane|lamellipodium|cell junction|,"negative regulation of transcription from RNA polymerase II promoter|response to hypoxia|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|cell adhesion|calcium-dependent cell-cell adhesion|lamellipodium assembly|regulation of cell migration|regulation of cell migration|gene silencing by RNA|positive regulation of cellular biosynthetic process|positive regulation of protein complex assembly|negative regulation of kinase activity|positive regulation of kinase activity|cellular protein localization|gene silencing by miRNA|wound healing, spreading of epidermal cells|negative regulation of hippo signaling|regulation of GTPase activity|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of MAP kinase activity|glycerophospholipid biosynthetic process|focal adhesion assembly|regulation of cellular response to hypoxia|positive regulation of gene silencing by miRNA|regulation of RNA biosynthetic process|",chromatin binding|transcription corepressor activity|transcription corepressor activity|transcription corepressor activity|protein binding|zinc ion binding|alpha-catenin binding|alpha-catenin binding|metal ion binding|actin filament binding|,10,0,0,10,0.2,1.13,0.1,0.0494,0.0494,0.858,0,0,-1.2,1.7
ENSMUSG00000062906,HDAC10,histone deacetylase 10,histone deacetylase complex|nucleus|nucleoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|protein deacetylation|chromatin modification|histone deacetylation|negative regulation of transcription, DNA-templated|",histone deacetylase activity|hydrolase activity|enzyme binding|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|protein deacetylase activity|histone deacetylase activity (H4-K16 specific)|histone deacetylase binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,0,0,10,0.4,1.19,0.1,0.0493,0.0493,0.858,0,0,-0.9,1.9
ENSMUSG00000068580,ZFYVE19,"zinc finger, FYVE domain containing 19",cytoplasm|centrosome|cytoskeleton|midbody|cleavage furrow|,cell cycle|abscission|cytokinesis checkpoint|negative regulation of cytokinesis|cell division|,zinc ion binding|lipid binding|phosphatidylinositol-3-phosphate binding|metal ion binding|,10,0,0,10,0.3,0.739,0.1,0.0462,0.0462,0.859,0,0,-1.2,1.6
ENSMUSG00000072115,ANG,"angiogenin, ribonuclease, RNase A family, 5",extracellular region|proteinaceous extracellular matrix|basement membrane|basal lamina|extracellular space|nucleus|growth cone|angiogenin-PRI complex|neuronal cell body|extracellular vesicular exosome|,angiogenesis|response to hypoxia|positive regulation of endothelial cell proliferation|diacylglycerol biosynthetic process|response to stress|activation of phospholipase C activity|multicellular organismal development|central nervous system development|rRNA transcription|response to hormone|cell migration|negative regulation of translation|cell differentiation|activation of protein kinase B activity|activation of phospholipase A2 activity|positive regulation of phosphorylation|negative regulation of smooth muscle cell proliferation|positive regulation of protein secretion|RNA phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis|,nucleic acid binding|DNA binding|RNA binding|actin binding|nuclease activity|endonuclease activity|ribonuclease activity|ribonuclease activity|receptor binding|copper ion binding|heparin binding|hydrolase activity|peptide binding|,10,0.3,2.18,10,-0.2,0.823,-0.1,0.0451,-0.0451,0.859,0,0,-1.7,1.4
ENSMUSG00000050222,IL17D,interleukin 17D,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.00806,10,0.1,0.0734,0.1,0.0447,0.0447,0.859,0,0,-1.3,1.6
ENSMUSG00000040855,REPS2,RALBP1 associated Eps domain containing protein 2,cellular_component|cytoplasm|,biological_process|,molecular_function|calcium ion binding|metal ion binding|,10,0,0,10,-0.1,0.41,-0.1,0.0446,-0.0446,0.859,0,0,-1.5,1.4
ENSMUSG00000051498,TLR6,toll-like receptor 6,plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|Toll-like receptor 2-Toll-like receptor 6 protein complex|,microglial cell activation|toll-like receptor signaling pathway|immune system process|MyD88-dependent toll-like receptor signaling pathway|inflammatory response|immune response|signal transduction|response to bacterial lipoprotein|toll-like receptor 6 signaling pathway|T-helper 1 type immune response|detection of diacyl bacterial lipopeptide|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of JUN kinase activity|positive regulation of interleukin-12 biosynthetic process|innate immune response|positive regulation of interleukin-6 biosynthetic process|nitric oxide metabolic process|regulation of cytokine secretion|cellular response to diacyl bacterial lipopeptide|,transmembrane signaling receptor activity|diacyl lipopeptide binding|protein heterodimerization activity|lipopeptide binding|lipopeptide binding|,10,0,0,10,0.2,0.543,0.1,0.0436,0.0436,0.86,0,0,-0.9,1.9
ENSMUSG00000019820,UTRN,utrophin,nucleus|cytoplasm|plasma membrane|dystrophin-associated glycoprotein complex|filopodium|growth cone|cortical actin cytoskeleton|filopodium membrane|neuromuscular junction|neuromuscular junction|protein complex|synapse|extracellular vesicular exosome|contractile ring|,positive regulation of cell-matrix adhesion|adult somatic muscle development|neuromuscular junction development|,actin binding|integrin binding|protein binding|vinculin binding|protein kinase binding|actin filament binding|,9,0.2,1.15,9,0,0,0.1,0.0434,0.0434,0.86,0,0,-1.2,1.8
ENSMUSG00000048910,FAM220A,"family with sequence similarity 220, member A",cellular_component|nucleus|,biological_process|,molecular_function|,10,0.1,0.109,10,0,0,0.1,0.0428,0.0428,0.86,0,0,-1.3,1.6
ENSMUSG00000030350,PRMT8,protein arginine N-methyltransferase 8,cytoplasm|cytosol|plasma membrane|plasma membrane|plasma membrane|membrane|,"regulation of transcription, DNA-templated|protein methylation|histone methylation|peptidyl-arginine methylation|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|methylation|histone arginine methylation|histone arginine methylation|histone H4-R3 methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N monomethyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|identical protein binding|protein homodimerization activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|histone methyltransferase activity (H4-R3 specific)|protein heterodimerization activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0.2,1.16,0.1,0.0418,0.0418,0.86,0,0,-1.2,1.7
ENSMUSG00000030059,TMF1,TATA element modulatory factor 1,cell|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|membrane|,"acrosome assembly|positive regulation of cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|spermatid development|spermatid nucleus differentiation|male gonad development|negative regulation of gene expression|sperm motility|luteinizing hormone secretion|Leydig cell differentiation|defense response to bacterium|negative regulation of apoptotic process|regulation of proteasomal protein catabolic process|cellular response to organic cyclic compound|positive regulation of testosterone secretion|",DNA binding|protein binding|,10,-0.1,0.179,10,0,0,-0.1,0.0407,-0.0407,0.86,0,0,-1.8,1
ENSMUSG00000027750,POSTN,"periostin, osteoblast specific factor",extracellular region|proteinaceous extracellular matrix|Golgi apparatus|trans-Golgi network|extracellular matrix|,cell adhesion|cell adhesion|regulation of Notch signaling pathway|tissue development|extracellular matrix organization|,heparin binding|,10,-0.2,0.465,10,0,0,0.1,0.0403,0.0403,0.861,0,0,-1.3,1.6
ENSMUSG00000036928,STAG3,stromal antigen 3,"chromosome, centromeric region|condensed nuclear chromosome|synaptonemal complex|lateral element|transverse filament|male germ cell nucleus|extracellular space|nucleus|chromosome|nucleolus|meiotic cohesin complex|meiotic cohesin complex|nuclear meiotic cohesin complex|",cell cycle|chromosome segregation|male meiosis sister chromatid cohesion|female meiosis sister chromatid cohesion|meiotic nuclear division|,protein binding|,10,0.1,0.144,10,0,0,0.1,0.0368,0.0368,0.861,0,0,-1.3,1.6
ENSMUSG00000047878,A4GALT,"alpha 1,4-galactosyltransferase",Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,globoside biosynthetic process|globoside biosynthetic process|lipid metabolic process|plasma membrane organization|,"galactosyltransferase activity|toxic substance binding|transferase activity|transferase activity, transferring glycosyl groups|lactosylceramide 4-alpha-galactosyltransferase activity|lactosylceramide 4-alpha-galactosyltransferase activity|",10,0,0,10,0.2,0.433,0.1,0.0336,0.0336,0.862,0,0,-1.3,1.5
ENSMUSG00000048978,NRSN1,neurensin 1,membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|transport vesicle|growth cone|neuron projection|neuronal cell body|,biological_process|,molecular_function|,10,0,0,10,0.2,0.653,0.1,0.0336,0.0336,0.862,0,0,-1.1,1.8
ENSMUSG00000028476,RECK,reversion-inducing-cysteine-rich protein with kazal motifs,plasma membrane|membrane|anchored component of membrane|,blood vessel maturation|blood vessel maturation|embryo implantation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|extracellular matrix organization|positive regulation of Notch signaling pathway|,endopeptidase inhibitor activity|endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.2,0.486,10,0,0,0.1,0.0286,0.0286,0.863,0,0,-1,1.8
ENSMUSG00000038690,ATP5J2,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2","mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|nucleus|mitochondrion|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|integral component of membrane|proton-transporting ATP synthase complex, coupling factor F(o)|extracellular vesicular exosome|",ATP catabolic process|ATP biosynthetic process|transport|ion transport|proton transport|ATP metabolic process|,ATPase activity|,10,0.1,0.0521,10,-0.2,0.391,-0.2,0.0261,-0.0261,0.864,0,0,-1.9,0.8
ENSMUSG00000000957,MMP14,matrix metallopeptidase 14 (membrane-inserted),cytoplasm|cytoplasm|membrane|integral component of membrane|extracellular matrix|,"ossification|endochondral ossification|regulation of transcription, DNA-templated|proteolysis|response to hormone|positive regulation of peptidase activity|cell migration|positive regulation of cell growth|lung development|positive regulation of cell migration|collagen catabolic process|zymogen activation|chondrocyte proliferation|embryonic cranial skeleton morphogenesis|branching morphogenesis of an epithelial tube|tissue remodeling|negative regulation of focal adhesion assembly|bone development|craniofacial suture morphogenesis|",sequence-specific DNA binding transcription factor activity|metalloendopeptidase activity|integrin binding|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|peptidase activator activity|hydrolase activity|metal ion binding|,10,0.1,0.00254,10,0.1,0.0225,0.1,0.0228,0.0228,0.865,0,0,-1.1,1.8
ENSMUSG00000037411,SERPINE1,"serine (or cysteine) peptidase inhibitor, clade E, member 1",extracellular region|extracellular space|extracellular space|extracellular matrix|chromaffin granule|,female gonad development|negative regulation of peptidase activity|regulation of receptor activity|positive regulation of gene expression|negative regulation of gene expression|negative regulation of plasminogen activation|negative regulation of plasminogen activation|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|negative regulation of smooth muscle cell migration|positive regulation of blood coagulation|negative regulation of cell migration|positive regulation of interleukin-8 production|negative regulation of cell adhesion mediated by integrin|positive regulation of leukotriene production involved in inflammatory response|cellular response to drug|wound healing|regulation of cell proliferation|regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of fibroblast proliferation|positive regulation of receptor-mediated endocytosis|positive regulation of inflammatory response|positive regulation of coagulation|defense response to Gram-negative bacterium|defense response to Gram-negative bacterium|positive regulation of keratinocyte migration|negative regulation of fibrinolysis|negative regulation of vascular wound healing|negative regulation of vascular wound healing|cellular response to lipopolysaccharide|cellular response to interleukin-1|positive regulation of monocyte chemotaxis|positive regulation of calcium ion import|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of smooth muscle cell-matrix adhesion|negative regulation of endothelial cell apoptotic process|,protease binding|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|receptor binding|protein binding|peptidase inhibitor activity|,10,0,0,10,0.1,0.147,0.1,0.0222,0.0222,0.865,0,0,-1,1.8
ENSMUSG00000030208,EMP1,epithelial membrane protein 1,plasma membrane|membrane|integral component of membrane|,cell growth|,None,10,-1.4,0.339,10,0.3,1.08,0.1,0.0192,0.0192,0.866,0,0,-2,1.1
ENSMUSG00000031536,POLB,"polymerase (DNA directed), beta",synaptonemal complex|intracellular|nucleus|cytoplasm|microtubule|spindle microtubule|,"DNA replication|DNA-dependent DNA replication|DNA-dependent DNA replication|DNA repair|base-excision repair|base-excision repair|base-excision repair, gap-filling|base-excision repair, gap-filling|base-excision repair, gap-filling|pyrimidine dimer repair|cellular response to DNA damage stimulus|intrinsic apoptotic signaling pathway in response to DNA damage|neuron apoptotic process|DNA biosynthetic process|DNA biosynthetic process|",DNA binding|damaged DNA binding|DNA-directed DNA polymerase activity|DNA-directed DNA polymerase activity|microtubule binding|transferase activity|nucleotidyltransferase activity|lyase activity|enzyme binding|DNA polymerase activity|metal ion binding|,10,-0.1,0.0809,10,0,0,-0.1,0.0185,-0.0185,0.866,0,0,-1,1.9
ENSMUSG00000026829,GBGT1,"globoside alpha-1,3-N-acetylgalactosaminyltransferase 1",Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|lipid glycosylation|,"transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|metal ion binding|globoside alpha-N-acetylgalactosaminyltransferase activity|",10,-0.1,0.167,10,0,0,-0.1,0.0183,-0.0183,0.866,0,0,-1.7,1.1
ENSMUSG00000026923,NOTCH1,notch 1,acrosomal vesicle|MAML1-RBP-Jkappa- ICN1 complex|cell|nucleus|nucleus|nucleus|cytoplasm|Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|cell periphery|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|angiogenesis|in utero embryonic development|cell fate specification|epithelial to mesenchymal transition|liver development|heart looping|sprouting angiogenesis|osteoblast fate commitment|positive regulation of neuroblast proliferation|inflammatory response to antigenic stimulus|endocardium development|endocardium morphogenesis|atrioventricular node development|coronary vein morphogenesis|aortic valve morphogenesis|atrioventricular valve morphogenesis|pulmonary valve morphogenesis|mitral valve formation|epithelial to mesenchymal transition involved in endocardial cushion formation|endocardial cushion morphogenesis|cardiac chamber formation|cardiac ventricle morphogenesis|cardiac atrium morphogenesis|cardiac right atrium morphogenesis|cardiac left ventricle morphogenesis|cardiac right ventricle formation|ventricular trabecula myocardium morphogenesis|growth involved in heart morphogenesis|regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|regulation of cardioblast proliferation|Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation|cell migration involved in endocardial cushion formation|pericardium morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|humoral immune response|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|positive regulation of transcription of Notch receptor target|positive regulation of transcription of Notch receptor target|multicellular organismal development|spermatogenesis|determination of left/right symmetry|compartment pattern specification|axonogenesis|axonogenesis|foregut morphogenesis|endoderm development|heart development|heart development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|epidermis development|auditory receptor cell fate commitment|glial cell differentiation|regulation of gene expression|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|negative regulation of cell-substrate adhesion|negative regulation of myotube differentiation|mesenchymal cell development|regulation of somitogenesis|neural tube development|cell differentiation|neuron differentiation|keratinocyte differentiation|negative regulation of ossification|lung development|embryonic limb morphogenesis|regulation of cell migration|positive regulation of cell migration|positive regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|forebrain development|forebrain development|hair follicle morphogenesis|response to muramyl dipeptide|embryonic hindlimb morphogenesis|tube formation|skeletal muscle cell differentiation|cellular response to vascular endothelial growth factor stimulus|regulation of cell proliferation|anagen|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of catalytic activity|cell fate commitment|negative regulation of cell differentiation|positive regulation of endothelial cell differentiation|positive regulation of keratinocyte differentiation|positive regulation of keratinocyte differentiation|negative regulation of myoblast differentiation|negative regulation of neuron differentiation|negative regulation of neuron differentiation|negative regulation of neuron differentiation|negative regulation of osteoblast differentiation|positive regulation of glial cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of calcium ion-dependent exocytosis|positive regulation of JAK-STAT cascade|negative regulation of photoreceptor cell differentiation|somatic stem cell division|somatic stem cell division|neuron fate commitment|astrocyte differentiation|positive regulation of astrocyte differentiation|negative regulation of oligodendrocyte differentiation|branching morphogenesis of an epithelial tube|regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|regulation of neurogenesis|negative regulation of neurogenesis|regulation of developmental process|cardiac muscle tissue morphogenesis|cardiac muscle cell proliferation|positive regulation of cardiac muscle cell proliferation|negative regulation of glial cell proliferation|cardiac epithelial to mesenchymal transition|cardiac septum morphogenesis|ventricular septum morphogenesis|secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development|negative regulation of cell death|prostate gland epithelium morphogenesis|regulation of epithelial cell proliferation involved in prostate gland development|arterial endothelial cell differentiation|venous endothelial cell differentiation|cardiac vascular smooth muscle cell development|endocardial cell differentiation|vasculogenesis involved in coronary vascular morphogenesis|coronary artery morphogenesis|Notch signaling involved in heart development|Notch signaling involved in heart development|Notch signaling involved in heart development|regulation of cell adhesion involved in heart morphogenesis|heart trabecula morphogenesis|positive regulation of transcription from RNA polymerase II promoter in response to hypoxia|left/right axis specification|cellular response to follicle-stimulating hormone stimulus|interleukin-4 secretion|negative regulation of cell migration involved in sprouting angiogenesis|negative regulation of canonical Wnt signaling pathway|positive regulation of ephrin receptor signaling pathway|regulation of extracellular matrix assembly|apoptotic process involved in embryonic digit morphogenesis|negative regulation of stem cell differentiation|negative regulation of anoikis|negative regulation of pro-B cell differentiation|negative regulation of endothelial cell chemotaxis|",core promoter binding|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|chromatin binding|sequence-specific DNA binding transcription factor activity|enzyme inhibitor activity|receptor activity|calcium ion binding|protein binding|enzyme binding|chromatin DNA binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,-0.2,0.233,-0.1,0.0176,-0.0176,0.867,0,0,-1.4,1.6
ENSMUSG00000024959,BAD,BCL2-associated agonist of cell death,intracellular|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|cytosol|cytosol|membrane|,release of cytochrome c from mitochondria|glucose catabolic process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell proliferation|extrinsic apoptotic signaling pathway via death domain receptors|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of mitochondrial membrane potential|suppression by virus of host apoptotic process|suppression by virus of host apoptotic process|cytokine-mediated signaling pathway|positive regulation of insulin secretion|positive regulation of glucokinase activity|positive regulation of insulin secretion involved in cellular response to glucose stimulus|glucose homeostasis|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of cysteine-type endopeptidase activity involved in apoptotic process|type B pancreatic cell proliferation|positive regulation of B cell differentiation|positive regulation of T cell differentiation|positive regulation of proteolysis|ADP metabolic process|ATP metabolic process|regulation of mitochondrial membrane permeability|pore complex assembly|positive regulation of epithelial cell proliferation|positive regulation of apoptotic process by virus|cellular process regulating host cell cycle in response to virus|cellular response to organic substance|cellular response to nicotine|positive regulation of release of cytochrome c from mitochondria|apoptotic signaling pathway|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|extrinsic apoptotic signaling pathway in absence of ligand|extrinsic apoptotic signaling pathway in absence of ligand|intrinsic apoptotic signaling pathway|activation of cysteine-type endopeptidase activity|positive regulation of neuron death|positive regulation of type B pancreatic cell development|,protein binding|phospholipid binding|lipid binding|cysteine-type endopeptidase activator activity involved in apoptotic process|cysteine-type endopeptidase activator activity involved in apoptotic process|protein kinase binding|protein phosphatase binding|protein phosphatase 2B binding|protein kinase B binding|protein heterodimerization activity|,10,-0.1,0.276,10,0,0,-0.1,0.0169,-0.0169,0.867,0,0,-1.6,1.3
ENSMUSG00000039357,FUT11,fucosyltransferase 11,Golgi membrane|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,protein glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.1,0.259,10,-0.2,0.906,-0.1,0.0154,-0.0154,0.867,0,0,-1.5,1.3
ENSMUSG00000066677,PYDC3,pyrin domain containing 3,nucleus|nucleolus|cytoplasm|membrane|,biological_process|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,10,0,0,10,-0.4,2.1,-0.3,0.0154,-0.0154,0.867,0,0,-1.7,1.1
ENSMUSG00000032691,NLRP3,"NLR family, pyrin domain containing 3",cell|cytoplasm|NLRP3 inflammasome complex|,negative regulation of acute inflammatory response|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|inflammatory response|negative regulation of NF-kappaB transcription factor activity|interleukin-1 beta production|interleukin-18 production|negative regulation of NF-kappaB import into nucleus|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|NLRP3 inflammasome complex assembly|interleukin-1 secretion|negative regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|regulation of inflammatory response|negative regulation of inflammatory response|positive regulation of NF-kappaB transcription factor activity|defense response to virus|cellular response to lipopolysaccharide|,nucleotide binding|protein binding|ATP binding|,10,0.2,0.288,10,0,0,0.1,0.0148,0.0148,0.867,0,0,-1.6,1.5
ENSMUSG00000002108,NR1H3,"nuclear receptor subfamily 1, group H, member 3",nuclear chromatin|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|fatty acid biosynthetic process|positive regulation of triglyceride biosynthetic process|positive regulation of receptor biosynthetic process|positive regulation of cholesterol efflux|positive regulation of cholesterol efflux|negative regulation of cholesterol storage|negative regulation of cholesterol storage|intracellular receptor signaling pathway|positive regulation of cellular protein metabolic process|negative regulation of lipid transport|positive regulation of cholesterol transport|response to progesterone|positive regulation of toll-like receptor 4 signaling pathway|cholesterol homeostasis|negative regulation of macrophage activation|apoptotic cell clearance|steroid hormone mediated signaling pathway|cellular lipid metabolic process|positive regulation of fatty acid biosynthetic process|negative regulation of proteolysis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of pinocytosis|negative regulation of inflammatory response|positive regulation of lipoprotein lipase activity|lipid homeostasis|lipid homeostasis|sterol homeostasis|triglyceride homeostasis|triglyceride homeostasis|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|negative regulation of pancreatic juice secretion|negative regulation of secretion of lysosomal enzymes|regulation of cholesterol homeostasis|positive regulation of cholesterol homeostasis|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|zinc ion binding|sterol response element binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|retinoid X receptor binding|protein heterodimerization activity|,10,0,0,10,-0.2,0.52,0.1,0.00627,0.00627,0.87,0,0,-2,1
ENSMUSG00000038210,HOXA11,homeobox A11,nucleus|transcription factor complex|protein-DNA complex|protein complex|,"skeletal system development|skeletal system development|metanephros development|branching involved in ureteric bud morphogenesis|organ induction|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|single fertilization|mesodermal cell fate specification|male gonad development|anterior/posterior pattern specification|dorsal/ventral pattern formation|proximal/distal pattern formation|regulation of gene expression|positive regulation of cell development|embryonic limb morphogenesis|regulation of chondrocyte differentiation|positive regulation of chondrocyte differentiation|embryonic forelimb morphogenesis|embryonic digit morphogenesis|positive regulation of transcription, DNA-templated|developmental growth|uterus development|embryonic skeletal joint morphogenesis|cartilage development involved in endochondral bone morphogenesis|",DNA binding|protein binding|sequence-specific DNA binding|,10,0.7,0.316,10,-0.2,0.108,-0.1,0.00481,-0.00481,0.87,0,0,-1.1,1.9
ENSMUSG00000024975,PDCD4,programmed cell death 4,nucleus|cytoplasm|cytosol|,"apoptotic process|cell aging|negative regulation of transcription, DNA-templated|",RNA binding|protein binding|,10,0,0,10,-0.3,0.548,-0.1,0.00407,-0.00407,0.87,0,0,-1.5,1.4
ENSMUSG00000042515,MUM1L1,melanoma associated antigen (mutated) 1-like 1,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,0.6,10,-0.1,0.0713,0.1,0.00272,0.00272,0.871,0,0,-1,1.8
ENSMUSG00000043811,RTN4R,reticulon 4 receptor,endoplasmic reticulum|plasma membrane|cell surface|membrane|growth cone|anchored component of membrane|,axonogenesis|,protein binding|,10,-0.1,0.105,10,0,0,-0.1,0.00216,-0.00216,0.871,0,0,-2,0.9
ENSMUSG00000004032,GSTM5,"glutathione S-transferase, mu 5",nucleus|cytoplasm|sperm fibrous sheath|extracellular vesicular exosome|,glutathione metabolic process|metabolic process|nitrobenzene metabolic process|xenobiotic catabolic process|cellular detoxification of nitrogen compound|,glutathione transferase activity|glutathione transferase activity|protein binding|transferase activity|enzyme binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|glutathione binding|,10,0,0,10,0.2,0.64,0.1,0.00205,0.00205,0.871,0,0,-1.9,1
ENSMUSG00000033191,TIE1,tyrosine kinase with immunoglobulin-like and EGF-like domains 1,plasma membrane|membrane|integral component of membrane|,angiogenesis|blood vessel development|vasculogenesis|in utero embryonic development|protein phosphorylation|phosphorylation|negative regulation of angiogenesis|negative regulation of cell migration|response to retinoic acid|plasma membrane fusion|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.3,0.45,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000034041,LYL1,lymphoblastomic leukemia 1,nucleus|,"blood vessel maturation|transcription, DNA-templated|regulation of transcription, DNA-templated|B cell differentiation|positive regulation of transcription, DNA-templated|definitive hemopoiesis|",DNA binding|protein dimerization activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000056643,CHST13,carbohydrate (chondroitin 4) sulfotransferase 13,cellular_component|,chondroitin sulfate biosynthetic process|,N-acetylgalactosamine 4-O-sulfotransferase activity|chondroitin 4-sulfotransferase activity|,10,0,0,10,-0.1,0.204,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000030960,METTL10,methyltransferase like 10,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0.1,0.148,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000026208,DES,desmin,intracellular|cytoplasm|cytoskeleton|intermediate filament|fascia adherens|gap junction|Z disc|Z disc|neuromuscular junction|sarcolemma|contractile fiber|type III intermediate filament|,muscle organ development|,structural molecule activity|structural constituent of cytoskeleton|protein binding|cytoskeletal protein binding|identical protein binding|,10,0,0,10,0.1,0.00333,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000039057,MYO16,myosin XVI,intracellular|nucleoplasm|cytoplasm|myosin complex|perinuclear region of cytoplasm|,phosphatidylinositol 3-kinase signaling|neuron projection morphogenesis|,nucleotide binding|motor activity|actin binding|protein binding|ATP binding|,10,0,0,10,0.2,1.03,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000069581,TSPEAR,thrombospondin type laminin G domain and EAR repeats,extracellular region|cell surface|stereocilium|cell projection|ciliary membrane|,sensory perception of sound|,molecular_function|,10,0.5,0.873,10,0,0,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000015363,TRABD,TraB domain containing,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.179,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000044407,QK,quaking,nucleus|cytoplasm|,vasculogenesis|mRNA processing|regulation of translation|transport|multicellular organismal development|spermatid development|axon ensheathment|RNA splicing|positive regulation of gene expression|cell differentiation|myelination|muscle cell differentiation|long-chain fatty acid biosynthetic process|mRNA transport|3'-UTR-mediated mRNA destabilization|,RNA binding|mRNA binding|SH3 domain binding|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000033427,UPB1,"ureidopropionase, beta",cytoplasm|extracellular vesicular exosome|,liver development|nitrogen compound metabolic process|metabolic process|beta-alanine metabolic process|,"catalytic activity|beta-ureidopropionase activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|metal ion binding|",10,0,0,10,0.2,0.491,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000037171,NODAL,nodal,extracellular region|extracellular space|extracellular space|,negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|gastrulation with mouth forming second|mesoderm formation|mesoderm formation|trophectodermal cell differentiation|trophectodermal cellular morphogenesis|neural fold formation|liver development|placenta development|embryonic placenta development|maternal placenta development|vasculature development|heart looping|inhibition of neuroepithelial cell differentiation|transforming growth factor beta receptor signaling pathway|multicellular organismal development|determination of left/right symmetry|determination of left/right symmetry|determination of left/right symmetry|determination of left/right symmetry|gastrulation|nervous system development|brain development|endoderm development|heart development|positive regulation of cell proliferation|embryonic pattern specification|anterior/posterior axis specification|anterior/posterior pattern specification|anterior/posterior pattern specification|regulation of signal transduction|polarity specification of proximal/distal axis|regulation of gastrulation|positive regulation vascular endothelial growth factor production|positive regulation of pathway-restricted SMAD protein phosphorylation|cell migration|stem cell maintenance|stem cell maintenance|positive regulation of cell-cell adhesion|lung development|positive regulation of activin receptor signaling pathway|floor plate morphogenesis|embryonic heart tube development|endodermal cell differentiation|nodal signaling pathway|growth|cell migration involved in gastrulation|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|cell fate commitment|negative regulation of cell differentiation|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|axial mesodermal cell fate specification|mesendoderm development|mesendoderm development|digestive tract morphogenesis|anatomical structure formation involved in morphogenesis|embryonic cranial skeleton morphogenesis|tissue morphogenesis|formation of anatomical boundary|positive regulation of epithelial cell proliferation|positive regulation of sequence-specific DNA binding transcription factor activity|digestive system development|embryonic process involved in female pregnancy|maternal process involved in parturition|positive regulation of SMAD protein import into nucleus|SMAD protein signal transduction|left lung morphogenesis|negative regulation of androgen receptor signaling pathway|epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification|positive regulation of ERK1 and ERK2 cascade|primitive streak formation|transforming growth factor beta receptor signaling pathway involved in primitive streak formation|nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of trophoblast cell migration|negative regulation of chorionic trophoblast cell proliferation|positive regulation of receptor activity|,cytokine activity|protein binding|growth factor activity|receptor agonist activity|type I activin receptor binding|,10,0,0,10,0.2,0.493,0,0,0,0.871,0,0,-1.2,1.7
ENSMUSG00000021938,PSPC1,paraspeckle protein 1,nucleus|nucleoplasm|cytoplasm|paraspeckles|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of circadian rhythm|negative regulation of transcription, DNA-templated|",nucleotide binding|core promoter binding|nucleic acid binding|RNA binding|protein binding|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-2,0.9
ENSMUSG00000025014,DNTT,"deoxynucleotidyltransferase, terminal",nucleus|nucleus|cytoplasm|,DNA metabolic process|DNA modification|,DNA binding|DNA-directed DNA polymerase activity|DNA nucleotidylexotransferase activity|transferase activity|nucleotidyltransferase activity|DNA polymerase activity|metal ion binding|,10,0,0,10,-1.3,2.92,0,0,0,0.871,0,0,-2,0.7
ENSMUSG00000006586,RUNX1T1,"runt-related transcription factor 1; translocated to, 1 (cyclin D-related)",nucleus|nuclear matrix|,"transcription, DNA-templated|regulation of transcription, DNA-templated|fat cell differentiation|regulation of DNA binding|",sequence-specific DNA binding transcription factor activity|protein binding|identical protein binding|protein homodimerization activity|metal ion binding|,10,0,0,10,0.1,0.53,0,0,0,0.871,0,0,-1.5,1.4
ENSMUSG00000034563,CCPG1,cell cycle progression 1,membrane|integral component of membrane|,cell cycle|positive regulation of cell proliferation|positive regulation of cell cycle|positive regulation of transcription from RNA polymerase II promoter|regulation of Rho guanyl-nucleotide exchange factor activity|,protein binding|,10,-0.1,0.0238,10,0.2,0.566,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000029528,PXN,paxillin,nucleus|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|focal adhesion|focal adhesion|lamellipodium|lamellipodium|cell junction|cell leading edge|,activation of MAPK activity|cellular component movement|cytoskeleton organization|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|integrin-mediated signaling pathway|regulation of cell shape|peptidyl-tyrosine phosphorylation|lamellipodium assembly|substrate adhesion-dependent cell spreading|positive regulation of protein kinase activity|focal adhesion assembly|branching morphogenesis of an epithelial tube|growth hormone receptor signaling pathway|,integrin binding|protein binding|beta-catenin binding|zinc ion binding|vinculin binding|protein kinase binding|receptor signaling complex scaffold activity|protein complex binding|metal ion binding|BH4 domain binding|,10,0.1,0.01,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000000182,FGF23,fibroblast growth factor 23,extracellular region|extracellular space|,"fibroblast growth factor receptor signaling pathway|regulation of phosphate transport|positive regulation of vitamin D 24-hydroxylase activity|cell differentiation|regulation of bone mineralization|negative regulation of bone mineralization|cellular phosphate ion homeostasis|vitamin D catabolic process|negative regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|negative regulation of hormone secretion|phosphate ion homeostasis|positive regulation of ERK1 and ERK2 cascade|positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway|",fibroblast growth factor receptor binding|type 1 fibroblast growth factor receptor binding|protein binding|growth factor activity|,10,0,0,10,-0.1,0.238,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000018507,TRPV2,"transient receptor potential cation channel, subfamily V, member 2",intracellular|cytoplasm|plasma membrane|plasma membrane|cell surface|endomembrane system|membrane|integral component of membrane|axon|growth cone membrane|axonal growth cone|cell body|,transport|ion transport|cation transport|calcium ion transport|response to temperature stimulus|response to heat|ion transmembrane transport|positive regulation of axon extension|transmembrane transport|calcium ion transmembrane transport|positive regulation of calcium ion import|,ion channel activity|cation channel activity|cation channel activity|calcium channel activity|,10,0,0,10,0.2,0.291,0,0,0,0.871,0,0,-1.2,1.7
ENSMUSG00000025231,SUFU,suppressor of fused homolog (Drosophila),cell|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|cilium|primary cilium|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|neural tube closure|heart looping|determination of left/right symmetry|spinal cord dorsal/ventral patterning|smoothened signaling pathway involved in ventral spinal cord interneuron specification|smoothened signaling pathway involved in spinal cord motor neuron cell fate specification|cytoplasmic sequestering of transcription factor|skin development|negative regulation of smoothened signaling pathway|negative regulation of smoothened signaling pathway|negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,protein binding|beta-catenin binding|transcription factor binding|protein kinase binding|,10,0.5,1.61,10,0,0,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000022456,3-Sep,septin 3,cytoplasm|cytosol|cytoskeleton|cell junction|septin complex|presynaptic membrane|neuron projection|synapse|,cell cycle|cell division|,nucleotide binding|GTP binding|,10,0,0,10,-0.2,0.927,0,0,0,0.871,0,0,-1.7,1.2
ENSMUSG00000063903,KLK1,kallikrein 1,nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000020287,MPG,N-methylpurine-DNA glycosylase,nucleus|cytoplasm|mitochondrion|mitochondrial nucleoid|,DNA repair|base-excision repair|cellular response to DNA damage stimulus|,DNA binding|catalytic activity|alkylbase DNA N-glycosylase activity|alkylbase DNA N-glycosylase activity|DNA-3-methyladenine glycosylase activity|hydrolase activity|DNA-7-methylguanine glycosylase activity|DNA-7-methyladenine glycosylase activity|DNA-3-methylguanine glycosylase activity|,10,1.4,2.29,10,0,0,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000048078,TENM4,teneurin transmembrane protein 4,nucleus|cytoplasm|integral component of plasma membrane|membrane|integral component of membrane|cell projection|neuron projection|,gastrulation with mouth forming second|signal transduction|multicellular organismal development|cell differentiation|positive regulation of myelination|central nervous system myelin formation|neuron development|positive regulation of oligodendrocyte differentiation|cardiac muscle cell proliferation|cardiac cell fate specification|self proteolysis|positive regulation of gastrulation|,protein homodimerization activity|,10,0,0,10,-0.1,0.135,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000020679,HNF1B,HNF1 homeobox B,cell|nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|endoderm formation|endodermal cell fate specification|kidney development|kidney development|inner cell mass cell differentiation|liver development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|endoderm development|response to glucose|embryo development|anterior/posterior pattern specification|positive regulation of gene expression|insulin secretion|regulation of Wnt signaling pathway|hindbrain development|endocrine pancreas development|circadian regulation of gene expression|regulation of pronephros size|pronephric nephron tubule development|regulation of endodermal cell fate specification|negative regulation of apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic digestive tract morphogenesis|branching morphogenesis of an epithelial tube|pronephros development|genitalia development|epithelial cell proliferation|positive regulation of transcription initiation from RNA polymerase II promoter|epithelium development|ureteric bud elongation|kidney morphogenesis|hepatoblast differentiation|negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis|protein-DNA complex assembly|regulation of branch elongation involved in ureteric bud branching|mesonephric tubule development|nephric duct development|mesonephric duct development|nephric duct formation|mesonephric duct formation|negative regulation of mesenchymal cell apoptotic process involved in metanephros development|",core promoter proximal region DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|protein complex binding|protein homodimerization activity|protein homodimerization activity|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000042750,BEX2,brain expressed X-linked 2,nucleus|transcription factor complex|cytoplasm|,apoptotic process|cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of sequence-specific DNA binding transcription factor activity|,RNA polymerase II activating transcription factor binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000025215,TLX1,"T cell leukemia, homeobox 1",nucleus|,central nervous system development|positive regulation of cell proliferation|neuron differentiation|cell fate commitment|positive regulation of transcription from RNA polymerase II promoter|lymph node development|spleen development|spleen development|organ formation|,DNA binding|protein heterodimerization activity|,10,0.6,0.0479,10,0.1,0.154,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000031952,CHST5,carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5,Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|N-acetylglucosamine metabolic process|N-acetylglucosamine metabolic process|sulfur compound metabolic process|sulfur compound metabolic process|keratan sulfate biosynthetic process|keratan sulfate biosynthetic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.3
ENSMUSG00000033819,PPP1R16A,"protein phosphatase 1, regulatory (inhibitor) subunit 16A",cytosol|plasma membrane|membrane|,biological_process|,molecular_function|,10,0.1,0.311,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000025533,ASL,argininosuccinate lyase,nucleus|cytoplasm|mitochondrial outer membrane|endoplasmic reticulum|neuronal cell body|perikaryon|perinuclear region of cytoplasm|extracellular vesicular exosome|cell body fiber|,urea cycle|argininosuccinate metabolic process|liver development|internal protein amino acid acetylation|cellular amino acid metabolic process|arginine biosynthetic process|locomotory behavior|cellular amino acid biosynthetic process|post-embryonic development|ammonia assimilation cycle|arginine biosynthetic process via ornithine|,catalytic activity|argininosuccinate lyase activity|lyase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000026981,IL1RN,interleukin 1 receptor antagonist,extracellular region|extracellular space|cell|cytoplasm|vesicle|extracellular vesicular exosome|,fever generation|negative regulation of cytokine-mediated signaling pathway|lipid metabolic process|acute-phase response|memory|negative regulation of glutamate secretion|sensory perception of pain|insulin secretion|negative regulation of cell migration|negative regulation of heterotypic cell-cell adhesion|negative regulation of apoptotic process|positive regulation of JUN kinase activity|negative regulation of membrane potential|response to glucocorticoid|extracellular negative regulation of signal transduction|negative regulation of receptor activity|negative regulation of interleukin-1-mediated signaling pathway|,"interleukin-1 receptor binding|interleukin-1, Type I receptor binding|interleukin-1, Type II receptor binding|interleukin-1 receptor antagonist activity|interleukin-1 Type I receptor antagonist activity|interleukin-1 Type II receptor antagonist activity|",10,0.3,0.988,10,0,0,0,0,0,0.871,0,0,-0.9,1.9
ENSMUSG00000074004,B3GNT6,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)",Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000023348,TRIP6,thyroid hormone receptor interactor 6,nucleus|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|cell junction|interleukin-1 receptor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell adhesion|release of cytoplasmic sequestered NF-kappaB|positive regulation of cell migration|",interleukin-1 receptor binding|protein binding|zinc ion binding|kinase binding|poly(A) RNA binding|metal ion binding|,10,-0.1,0.175,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000059248,9-Sep,septin 9,stress fiber|cytoplasm|cytoskeleton|microtubule|actin cytoskeleton|perinuclear region of cytoplasm|,cell cycle|protein heterooligomerization|cell division|,nucleotide binding|GTP binding|,10,0,0,10,-0.1,0.125,0,0,0,0.871,0,0,-1,2
ENSMUSG00000050737,PTGES,prostaglandin E synthase,nuclear envelope lumen|cytoplasm|membrane|integral component of membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|negative regulation of cell proliferation|,prostaglandin-D synthase activity|isomerase activity|glutathione binding|prostaglandin-E synthase activity|,10,-0.1,0.0837,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000039831,ARHGAP29,Rho GTPase activating protein 29,intracellular|,signal transduction|intracellular signal transduction|,GTPase activator activity|protein binding|PDZ domain binding|metal ion binding|,10,0.1,0.286,10,-0.2,0.742,0,0,0,0.871,0,0,-1.5,1.4
ENSMUSG00000020486,4-Sep,septin 4,cytoplasm|mitochondrion|cytoskeleton|septin complex|motile cilium|sperm flagellum|cell projection|sperm part|sperm annulus|,cell cycle|spermatid development|brain development|sperm mitochondrion organization|positive regulation of protein ubiquitination|positive regulation of apoptotic process|sperm capacitation|cell division|positive regulation of intrinsic apoptotic signaling pathway|,nucleotide binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000041075,FZD7,frizzled homolog 7 (Drosophila),cytoplasm|plasma membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|neuron projection membrane|apical part of cell|,"vasculature development|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|Wnt signaling pathway, calcium modulating pathway|multicellular organismal development|axonogenesis|brain development|gonad development|embryo development|negative regulation of cell-substrate adhesion|negative regulation of cell-substrate adhesion|skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration|Wnt signaling pathway|stem cell maintenance|epithelial cell differentiation|T cell differentiation in thymus|substrate adhesion-dependent cell spreading|regulation of catenin import into nucleus|non-canonical Wnt signaling pathway|non-canonical Wnt signaling pathway via JNK cascade|positive regulation of phosphorylation|negative regulation of ectodermal cell fate specification|positive regulation of transcription, DNA-templated|somatic stem cell division|positive regulation of epithelial cell proliferation involved in wound healing|canonical Wnt signaling pathway|canonical Wnt signaling pathway|mesenchymal to epithelial transition|",signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|frizzled binding|protein binding|Wnt-protein binding|Wnt-protein binding|PDZ domain binding|PDZ domain binding|Wnt-activated receptor activity|,10,-0.1,0.208,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000007989,FZD3,frizzled homolog 3 (Drosophila),cytoplasm|cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|axon|dendrite|neuron projection membrane|neuronal cell body|apical part of cell|presynaptic active zone|,establishment of planar polarity|neuron migration|neural tube closure|vasculature development|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|multicellular organismal development|gonad development|Wnt signaling pathway|facial nucleus development|midbrain development|cell proliferation in midbrain|post-anal tail morphogenesis|inner ear morphogenesis|canonical Wnt signaling pathway|canonical Wnt signaling pathway|commissural neuron axon guidance|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|Wnt-protein binding|Wnt-protein binding|PDZ domain binding|PDZ domain binding|Wnt-activated receptor activity|,10,0,0,9,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000017801,MLX,MAX-like protein X,nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|nucleocytoplasmic transport|negative regulation of transcription, DNA-templated|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|protein binding|transcription factor binding|protein homodimerization activity|protein heterodimerization activity|protein dimerization activity|,10,-0.1,0.542,10,0.1,0.241,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000041954,TNFRSF18,"tumor necrosis factor receptor superfamily, member 18",extracellular region|plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,apoptotic process|,protein binding|,10,0,0,10,0.1,0.0578,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000047497,ADAMTS12,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12",extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|cell-matrix adhesion|cell migration|proteoglycan catabolic process|negative regulation of chondrocyte differentiation|regulation of inflammatory response|proteolysis involved in cellular protein catabolic process|cellular response to interleukin-1|cellular response to tumor necrosis factor|cellular response to BMP stimulus|regulation of endothelial tube morphogenesis|negative regulation of hepatocyte growth factor receptor signaling pathway|negative regulation of cellular response to vascular endothelial growth factor stimulus|negative regulation of cellular response to hepatocyte growth factor stimulus|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.126,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000037605,LPHN3,latrophilin 3,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|carbohydrate binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000091956,C2CD4B,C2 calcium-dependent domain containing 4B,nucleolus|focal adhesion|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000017697,ADA,adenosine deaminase,extracellular space|cytoplasm|cytoplasm|lysosome|cytosol|plasma membrane|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|cell junction|cytoplasmic vesicle|dendrite cytoplasm|neuronal cell body|,"response to hypoxia|in utero embryonic development|histamine secretion|trophectodermal cell differentiation|liver development|placenta development|germinal center B cell differentiation|positive regulation of germinal center formation|negative regulation of leukocyte migration|negative regulation of leukocyte migration|negative regulation of mature B cell apoptotic process|adenosine catabolic process|adenosine catabolic process|adenosine catabolic process|deoxyadenosine catabolic process|deoxyadenosine catabolic process|cell adhesion|nucleotide metabolic process|purine ribonucleoside monophosphate biosynthetic process|positive regulation of heart rate|lung development|positive regulation of B cell proliferation|purine nucleotide salvage|positive regulation of T cell differentiation in thymus|response to vitamin E|regulation of cell-cell adhesion mediated by integrin|T cell activation|negative regulation of circadian sleep/wake cycle, non-REM sleep|negative regulation of apoptotic process|hypoxanthine salvage|response to morphine|regulation of T cell differentiation|positive regulation of T cell differentiation|positive regulation of smooth muscle contraction|dATP catabolic process|dATP catabolic process|adenosine metabolic process|hypoxanthine biosynthetic process|inosine biosynthetic process|inosine biosynthetic process|inosine biosynthetic process|xanthine biosynthetic process|positive regulation of alpha-beta T cell differentiation|lung alveolus development|Peyer's patch development|embryonic digestive tract development|negative regulation of inflammatory response|negative regulation of inflammatory response|positive regulation of calcium-mediated signaling|positive regulation of T cell receptor signaling pathway|positive regulation of T cell activation|negative regulation of adenosine receptor signaling pathway|negative regulation of adenosine receptor signaling pathway|negative regulation of penile erection|negative regulation of thymocyte apoptotic process|negative regulation of mucus secretion|negative regulation of mucus secretion|",purine nucleoside binding|adenosine deaminase activity|adenosine deaminase activity|adenosine deaminase activity|zinc ion binding|zinc ion binding|hydrolase activity|deaminase activity|metal ion binding|,10,-0.7,0.32,10,0.1,0.687,0,0,0,0.871,0,0,-2,0.9
ENSMUSG00000026185,IGFBP5,insulin-like growth factor binding protein 5,extracellular region|insulin-like growth factor binding protein complex|,regulation of cell growth|glucose metabolic process|regulation of glucose metabolic process|negative regulation of smooth muscle cell migration|negative regulation of translation|negative regulation of cell migration|hair follicle morphogenesis|regulation of growth|glucose homeostasis|positive regulation of insulin-like growth factor receptor signaling pathway|negative regulation of insulin-like growth factor receptor signaling pathway|negative regulation of insulin-like growth factor receptor signaling pathway|type B pancreatic cell proliferation|negative regulation of osteoblast differentiation|negative regulation of smooth muscle cell proliferation|striated muscle cell differentiation|striated muscle cell differentiation|positive regulation of protein kinase B signaling|mammary gland involution|cellular response to cAMP|cellular response to organic cyclic compound|,fibronectin binding|insulin-like growth factor binding|insulin-like growth factor binding|growth factor binding|insulin-like growth factor I binding|,10,0,0,10,-0.1,0.0105,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000015312,GADD45B,growth arrest and DNA-damage-inducible 45 beta,nucleus|nucleus|cytoplasm|,activation of MAPKKK activity|activation of MAPKK activity|negative regulation of protein kinase activity|apoptotic process|response to stress|multicellular organismal development|cell differentiation|positive regulation of apoptotic process|positive regulation of JNK cascade|regulation of cell cycle|positive regulation of p38MAPK cascade|,protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000036570,FXYD1,FXYD domain-containing ion transport regulator 1,membrane|integral component of membrane|chloride channel complex|,transport|ion transport|chloride transport|cellular calcium ion homeostasis|muscle contraction|,ion channel activity|chloride channel activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.1
ENSMUSG00000029505,EP400,E1A binding protein p400,Swr1 complex|nucleus|nuclear speck|NuA4 histone acetyltransferase complex|,chromatin modification|histone H4 acetylation|histone H2A acetylation|,nucleotide binding|DNA binding|chromatin binding|helicase activity|protein binding|ATP binding|hydrolase activity|,10,-0.1,0.0172,10,0.3,0.478,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000038344,TXLNG,taxilin gamma,nucleus|cytoplasm|cytosol|membrane|nuclear membrane|nuclear membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|regulation of cell cycle process|regulation of bone mineralization|regulation of cell cycle|",protein binding|syntaxin binding|protein heterodimerization activity|protein heterodimerization activity|,10,0,0,10,0.2,0.301,0,0,0,0.871,0,0,-1.9,1
ENSMUSG00000028341,NR4A3,"nuclear receptor subfamily 4, group A, member 3",nucleus|transcription factor complex|,"mesoderm formation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|axon guidance|hippocampus development|adult behavior|inner ear morphogenesis|response to hydrogen peroxide|negative regulation of apoptotic process|steroid hormone mediated signaling pathway|negative regulation of neuron apoptotic process|positive regulation of cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|semicircular canal morphogenesis|neuromuscular process controlling balance|vestibular reflex|positive regulation of leukocyte apoptotic process|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000031165,WAS,Wiskott-Aldrich syndrome homolog (human),intracellular|cell|cytoplasm|cytoskeleton|cell-cell junction|vesicle membrane|extracellular vesicular exosome|,immune response|actin filament organization|actin polymerization or depolymerization|endosomal transport|actin filament polymerization|actin filament-based movement|T cell activation|positive regulation of Arp2/3 complex-mediated actin nucleation|,actin binding|protein binding|identical protein binding|identical protein binding|,10,0.1,0.0829,10,0,0,0,0,0,0.871,0,0,-1.4,1.5
ENSMUSG00000034118,TPST1,protein-tyrosine sulfotransferase 1,Golgi apparatus|membrane|integral component of membrane|,peptidyl-tyrosine sulfation|,protein-tyrosine sulfotransferase activity|transferase activity|,10,0.1,0.0806,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000020828,PLD2,phospholipase D2,nucleus|Golgi apparatus|plasma membrane|plasma membrane|caveola|membrane|lamellipodium|brush border membrane|sarcolemma|,response to hypoxia|G-protein coupled receptor internalization|lipid metabolic process|receptor-mediated endocytosis|metabolic process|phospholipid catabolic process|positive regulation of phosphatidylinositol 3-kinase signaling|response to organic cyclic compound|lipid catabolic process|positive regulation of cell migration|neuron projection development|response to hydrogen peroxide|positive regulation of mast cell degranulation|response to peptide hormone|positive regulation of cell adhesion|positive regulation of receptor-mediated endocytosis|,catalytic activity|phospholipase D activity|phospholipase D activity|protein kinase C binding|hydrolase activity|phosphatidylinositol binding|N-acylphosphatidylethanolamine-specific phospholipase D activity|,10,0,0,10,0.3,1.35,0,0,0,0.871,0,0,-1.3,1.6
ENSMUSG00000021986,AMER2,APC membrane recruitment 2,plasma membrane|membrane|,Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|,"protein binding|phosphatidylinositol-4,5-bisphosphate binding|lipid binding|",10,-0.6,2.27,10,0,0,0,0,0,0.871,0,0,-2,0.6
ENSMUSG00000066441,RDH11,retinol dehydrogenase 11,photoreceptor inner segment|endoplasmic reticulum|membrane|integral component of membrane|,metabolic process|adaptation of rhodopsin mediated signaling|retinol metabolic process|retinal metabolic process|oxidation-reduction process|,oxidoreductase activity|NADP-retinol dehydrogenase activity|,10,0,0,10,0.1,0.337,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000021136,SMOC1,SPARC related modular calcium binding 1,extracellular region|proteinaceous extracellular matrix|basement membrane|,eye development|eye development|signal transduction|multicellular organismal development|positive regulation of cell-substrate adhesion|cell differentiation|extracellular matrix organization|regulation of osteoblast differentiation|limb development|limb development|,calcium ion binding|metal ion binding|extracellular matrix binding|,10,0,0,10,0.2,0.664,0,0,0,0.871,0,0,-1.3,1.6
ENSMUSG00000029833,TRIM24,tripartite motif-containing 24,intracellular|nucleus|nucleus|nuclear euchromatin|perichromatin fibrils|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|negative regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of gene expression|positive regulation of gene expression|protein ubiquitination|protein ubiquitination|protein catabolic process|protein catabolic process|regulation of protein stability|regulation of protein stability|regulation of apoptotic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|protein autophosphorylation|calcium ion homeostasis|regulation of vitamin D receptor signaling pathway|cellular response to estrogen stimulus|regulation of signal transduction by p53 class mediator|regulation of RNA biosynthetic process|","p53 binding|p53 binding|DNA binding|chromatin binding|chromatin binding|transcription coactivator activity|transcription coactivator activity|protein kinase activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ligand-dependent nuclear receptor binding|ribosomal S6-glutamic acid ligase activity|estrogen response element binding|sequence-specific DNA binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|lysine-acetylated histone binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000015950,NCF1,neutrophil cytosolic factor 1,cytoplasm|rough endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|cytosol|plasma membrane|membrane|extrinsic component of membrane|dendrite|NADPH oxidase complex|neuronal cell body|,response to yeast|leukocyte mediated cytotoxicity|respiratory burst involved in defense response|protein targeting to membrane|leukotriene metabolic process|NADP catabolic process|apoptotic process|inflammatory response|cellular defense response|cell proliferation|response to bacterium|superoxide anion generation|superoxide anion generation|defense response to bacterium|respiratory burst|respiratory burst|negative regulation of smooth muscle contraction|hydrogen peroxide biosynthetic process|defense response to Gram-positive bacterium|defense response to fungus|oxidation-reduction process|oxidation-reduction process|neutrophil mediated killing of gram-positive bacterium|neutrophil mediated killing of fungus|,"protein binding|lipid binding|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|SH3 domain binding|phosphatidylinositol binding|phosphatidylinositol-3,4-bisphosphate binding|",10,0.1,0.133,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000037529,PRSS40,"protease, serine 40",extracellular region|cytoplasmic vesicle|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.00941,10,-0.5,1.69,0,0,0,0.871,0,0,-1.9,1
ENSMUSG00000026976,PAX8,paired box 8,nucleus|nucleus|nucleoplasm|transcription factor complex|,"urogenital system development|metanephros development|mesonephros development|transcription, DNA-templated|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|organ morphogenesis|cell differentiation|thyroid gland development|thyroid gland development|thyroid gland development|inner ear morphogenesis|regulation of apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|pronephros development|cellular response to gonadotropin stimulus|positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|metanephric distal convoluted tubule development|metanephric nephron tubule formation|negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis|regulation of metanephric nephron tubule epithelial cell differentiation|positive regulation of branching involved in ureteric bud morphogenesis|negative regulation of mesenchymal cell apoptotic process involved in metanephros development|negative regulation of apoptotic process involved in metanephric collecting duct development|negative regulation of apoptotic process involved in metanephric nephron tubule development|positive regulation of metanephric DCT cell differentiation|positive regulation of thyroid hormone generation|positive regulation of thyroid hormone generation|regulation of thyroid-stimulating hormone secretion|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000035673,SBNO2,strawberry notch homolog 2 (Drosophila),cellular_component|,"macrophage activation involved in immune response|macrophage activation involved in immune response|transcription, DNA-templated|regulation of transcription, DNA-templated|bone mineralization|osteoclast differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of inflammatory response|regulation of inflammatory response|bone trabecula morphogenesis|multinuclear osteoclast differentiation|osteoclast fusion|",protein binding|,10,0,0,10,-0.2,0.0521,0,0,0,0.871,0,0,-1.7,1.2
ENSMUSG00000036136,FAM110C,"family with sequence similarity 110, member C",nucleus|cytoplasm|cytoskeleton|microtubule|cell cortex|,positive regulation of cell migration|positive regulation of protein kinase B signaling|regulation of cell projection assembly|,alpha-tubulin binding|,10,0.2,0.0753,10,0,0,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000001819,HOXD13,homeobox D13,nucleus|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|pattern specification process|anterior/posterior pattern specification|gland morphogenesis|embryonic limb morphogenesis|male genitalia development|limb morphogenesis|limb morphogenesis|regulation of cell proliferation|embryonic digit morphogenesis|positive regulation of transcription from RNA polymerase II promoter|embryonic hindgut morphogenesis|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis|morphogenesis of an epithelial fold|branch elongation of an epithelium|regulation of branching involved in prostate gland morphogenesis|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000032035,ETS1,"E26 avian leukemia oncogene 1, 5' domain",nucleus|nucleus|transcription factor complex|cytoplasm|intercellular bridge|,"immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|positive regulation of endothelial cell migration|regulation of extracellular matrix disassembly|cell differentiation|positive regulation of cell migration|PML body organization|regulation of apoptotic process|positive regulation of erythrocyte differentiation|regulation of angiogenesis|positive regulation of angiogenesis|negative regulation of cell cycle|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|response to antibiotic|cell motility|positive regulation of cellular component movement|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|histone acetyltransferase binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.1
ENSMUSG00000074852,HPSE2,heparanase 2,extracellular region|proteinaceous extracellular matrix|membrane|,carbohydrate metabolic process|biological_process|,"hydrolase activity, acting on glycosyl bonds|heparan sulfate proteoglycan binding|",10,0.1,0.0684,10,0,0,0,0,0,0.871,0,0,-1.1,1.9
ENSMUSG00000062591,TUBB4A,"tubulin, beta 4A class IVA",nucleus|cytoplasm|cytoskeleton|microtubule|cilium|internode region of axon|cell projection|neuronal cell body|myelin sheath|protein complex|,GTP catabolic process|microtubule-based process|cell projection organization|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000036111,LMO1,LIM domain only 1,nucleus|,negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|,protein binding|zinc ion binding|metal ion binding|,10,-0.3,0.85,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000037608,BCLAF1,BCL2-associated transcription factor 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|positive regulation of apoptotic process|regulation of DNA-templated transcription in response to stress|negative regulation of transcription, DNA-templated|positive regulation of DNA-templated transcription, initiation|positive regulation of response to DNA damage stimulus|positive regulation of intrinsic apoptotic signaling pathway|",DNA binding|protein binding|poly(A) RNA binding|,10,0.1,0.123,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000000214,TH,tyrosine hydroxylase,nucleus|cytoplasm|cytoplasm|mitochondrion|smooth endoplasmic reticulum|cytosol|synaptic vesicle|cytoplasmic side of plasma membrane|axon|axon|dendrite|cytoplasmic vesicle membrane|cytoplasmic vesicle|melanosome membrane|neuron projection|neuron projection|neuronal cell body|terminal bouton|perikaryon|perikaryon|,"response to hypoxia|synaptic transmission, dopaminergic|dopamine biosynthetic process from tyrosine|dopamine biosynthetic process from tyrosine|dopamine biosynthetic process from tyrosine|dopamine biosynthetic process from tyrosine|heart development|heart development|visual perception|learning|memory|mating behavior|locomotory behavior|locomotory behavior|regulation of heart contraction|aromatic amino acid family metabolic process|organ morphogenesis|synaptic vesicle amine transport|neurotransmitter biosynthetic process|dopamine biosynthetic process|epinephrine biosynthetic process|norepinephrine biosynthetic process|catecholamine biosynthetic process|eye photoreceptor cell development|eating behavior|eating behavior|response to ethanol|embryonic camera-type eye morphogenesis|oxidation-reduction process|","monooxygenase activity|tyrosine 3-monooxygenase activity|tyrosine 3-monooxygenase activity|iron ion binding|ferrous iron binding|ferric iron binding|oxidoreductase activity|amino acid binding|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen|oxygen binding|protein domain specific binding|tetrahydrobiopterin binding|dopamine binding|metal ion binding|",10,0.1,0.205,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000054630,UGT2B5,"UDP glucuronosyltransferase 2 family, polypeptide B5",mitochondrial inner membrane|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,metabolic process|,"glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000017737,MMP9,matrix metallopeptidase 9,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|protein complex|extracellular vesicular exosome|,skeletal system development|skeletal system development|ossification|positive regulation of leukocyte migration|proteolysis|proteolysis|response to oxidative stress|embryo implantation|transformation of host cell by virus|extracellular matrix organization|extracellular matrix organization|collagen catabolic process|collagen catabolic process|positive regulation of synaptic plasticity|response to drug|positive regulation of apoptotic process|positive regulation of angiogenesis|negative regulation of fibroblast proliferation|tissue remodeling|leukocyte migration|protein oligomerization|positive regulation of keratinocyte migration|cellular response to cell-matrix adhesion|positive regulation of receptor binding|negative regulation of cation channel activity|,fibronectin binding|metalloendopeptidase activity|metalloendopeptidase activity|peptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|protein complex binding|identical protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000000320,ALOX12,arachidonate 12-lipoxygenase,cytoplasm|cytoplasm|cytosol|membrane|sarcolemma|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|cellular component movement|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of endothelial cell migration|positive regulation of gene expression|negative regulation of muscle cell apoptotic process|positive regulation of cell death|arachidonic acid metabolic process|arachidonic acid metabolic process|arachidonic acid metabolic process|lipoxygenase pathway|lipoxygenase pathway|lipoxygenase pathway|fatty acid oxidation|positive regulation of cell growth|positive regulation of cell migration|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of endothelial cell differentiation|positive regulation of angiogenesis|positive regulation of cell adhesion|positive regulation of vasodilation|positive regulation of smooth muscle cell proliferation|hepoxilin biosynthetic process|positive regulation of mitochondrial depolarization|oxidation-reduction process|establishment of skin barrier|negative regulation of platelet aggregation|lipoxin A4 biosynthetic process|lipoxin B4 biosynthetic process|,"arachidonate 12-lipoxygenase activity|arachidonate 12-lipoxygenase activity|iron ion binding|juvenile hormone epoxide hydrolase activity|linoleate 13S-lipoxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|hydrolase activity|epoxide hydrolase B activity|phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity|epoxide hydrolase A activity|phenanthrene-3,4-epoxide hydrolase activity|phenanthrene-1,2-epoxide hydrolase activity|phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity|phenanthrene-epoxide hydrolase activity|phenanthrene-9,10-epoxide hydrolase activity|pyrene-4,5-epoxide hydrolase activity|metal ion binding|dioxygenase activity|",10,0.2,0.148,10,0,0,0,0,0,0.871,0,0,-1.1,1.8
ENSMUSG00000035239,NEU3,neuraminidase 3,plasma membrane|membrane|,carbohydrate metabolic process|lipid metabolic process|ganglioside catabolic process|metabolic process|oligosaccharide catabolic process|lipid catabolic process|,"exo-alpha-sialidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|alpha-sialidase activity|exo-alpha-(2->3)-sialidase activity|exo-alpha-(2->6)-sialidase activity|exo-alpha-(2->8)-sialidase activity|",10,0,0,10,-0.1,0.546,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000015812,GNRH1,gonadotropin releasing hormone 1,extracellular region|extracellular space|,multicellular organismal development|regulation of gene expression|negative regulation of apoptotic process|response to ethanol|response to steroid hormone|regulation of ovarian follicle development|negative regulation of neuron migration|negative regulation of neuron migration|,hormone activity|gonadotropin hormone-releasing hormone activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.5
ENSMUSG00000032118,FEZ1,fasciculation and elongation protein zeta 1 (zygin I),cytoplasm|cytoplasm|mitochondrion|centrosome|cytoskeleton|microtubule|plasma membrane|microtubule cytoskeleton|membrane|axon|dendrite|cell projection|,transport|positive regulation of neuron projection development|positive regulation of neuron differentiation|establishment of mitochondrion localization|,protein kinase C binding|protein binding|gamma-tubulin binding|protein N-terminus binding|,9,-0.2,0.513,9,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000025812,PARD3,par-3 family cell polarity regulator,intracellular|cytoplasm|spindle|cytoskeleton|cell-cell junction|cell-cell junction|adherens junction|cell-cell adherens junction|tight junction|tight junction|cell cortex|membrane|cell junction|cell junction|internode region of axon|neuronal cell body|lateral loop|Schmidt-Lanterman incisure|protein complex|protein complex|axonal growth cone|apical part of cell|,"microtubule cytoskeleton organization|apical constriction|protein targeting to membrane|cell cycle|establishment or maintenance of cell polarity|negative regulation of peptidyl-threonine phosphorylation|single organismal cell-cell adhesion|myelination in peripheral nervous system|positive regulation of myelination|regulation of actin filament-based process|wound healing, spreading of cells|cell division|centrosome localization|regulation of cellular localization|tight junction assembly|establishment of epithelial cell polarity|","protein kinase C binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|lipid binding|protein phosphatase binding|phosphatidylinositol-3-phosphate binding|",10,0,0,10,0.3,0.595,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000004035,GSTM7,"glutathione S-transferase, mu 7",cytoplasm|sarcoplasmic reticulum|extracellular vesicular exosome|,glutathione metabolic process|metabolic process|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|nitrobenzene metabolic process|xenobiotic catabolic process|negative regulation of ryanodine-sensitive calcium-release channel activity|positive regulation of ryanodine-sensitive calcium-release channel activity|cellular detoxification of nitrogen compound|cellular response to caffeine|,glutathione transferase activity|receptor binding|transferase activity|enzyme binding|protein homodimerization activity|glutathione binding|,10,0,0,10,-0.1,0.132,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000024431,NR3C1,"nuclear receptor subfamily 3, group C, member 1",intracellular|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|cytosol|postsynaptic density|membrane|neuron projection|dendritic spine|protein complex|,"regulation of gluconeogenesis|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|glucocorticoid metabolic process|regulation of glucose metabolic process|positive regulation of glutamate secretion|chromatin modification|adrenal gland development|negative regulation of synaptic plasticity|regulation of glucocorticoid biosynthetic process|regulation of cell proliferation|maternal behavior|glucocorticoid receptor signaling pathway|glucocorticoid receptor signaling pathway|negative regulation of vascular permeability|steroid hormone mediated signaling pathway|glucocorticoid mediated signaling pathway|positive regulation of neuron apoptotic process|positive regulation of transcription from RNA polymerase II promoter|response to arsenic-containing substance|chromatin-mediated maintenance of transcription|mammary gland duct morphogenesis|positive regulation of dendritic spine development|positive regulation of cell growth involved in cardiac muscle cell development|cellular response to dexamethasone stimulus|negative regulation of glucocorticoid mediated signaling pathway|positive regulation of glucocorticoid receptor signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II regulatory region DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|transcription coactivator activity|glucocorticoid receptor activity|steroid binding|protein binding|transcription factor binding|zinc ion binding|lipid binding|Hsp70 protein binding|receptor tyrosine kinase binding|heat shock protein binding|protein complex binding|hormone binding|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|protein dimerization activity|Hsp90 protein binding|,10,0,0,10,0.1,0.121,0,0,0,0.871,0,0,-1.3,1.6
ENSMUSG00000034501,PCNXL4,pecanex-like 4 (Drosophila),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000076746,TCRG-V6,"T cell receptor gamma, variable 6",None,None,None,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000020205,PHLDA1,"pleckstrin homology-like domain, family A, member 1",nucleus|cytoplasm|membrane|cytoplasmic vesicle|,apoptotic process|positive regulation of apoptotic process|FasL biosynthetic process|,protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.8
ENSMUSG00000039153,RUNX2,runt related transcription factor 2,nuclear chromatin|nucleus|nucleus|transcription factor complex|cytoplasm|,"skeletal system development|osteoblast differentiation|osteoblast differentiation|endochondral ossification|osteoblast fate commitment|chondrocyte differentiation|chondrocyte differentiation|chondrocyte development|osteoblast development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|positive regulation of cell proliferation|T cell differentiation|regulation of ossification|BMP signaling pathway|positive regulation of chondrocyte differentiation|embryonic forelimb morphogenesis|regulation of fibroblast growth factor receptor signaling pathway|odontogenesis of dentin-containing tooth|regulation of odontogenesis of dentin-containing tooth|regulation of osteoblast differentiation|positive regulation of osteoblast differentiation|positive regulation of osteoblast differentiation|positive regulation of ossification|negative regulation of smoothened signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|cell maturation|embryonic cranial skeleton morphogenesis|skeletal system morphogenesis|stem cell differentiation|cellular response to BMP stimulus|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|ATP binding|transcription factor binding|protein domain specific binding|bHLH transcription factor binding|transcription regulatory region DNA binding|repressing transcription factor binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000003379,CD79A,CD79A antigen (immunoglobulin-associated alpha),multivesicular body|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|B cell receptor complex|membrane raft|,immune system process|cell surface receptor signaling pathway|B cell differentiation|B cell proliferation|B cell activation|B cell receptor signaling pathway|,transmembrane signaling receptor activity|protein binding|,10,0.1,0.0256,10,-0.1,0.157,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000071856,MCC,mutated in colorectal cancers,nucleus|cytoplasm|plasma membrane|,negative regulation of epithelial cell migration|negative regulation of epithelial cell proliferation|negative regulation of canonical Wnt signaling pathway|,None,10,0,0,10,0.3,0.769,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000023011,FAIM2,Fas apoptotic inhibitory molecule 2,plasma membrane|membrane|integral component of membrane|cell junction|membrane raft|membrane raft|synapse|postsynaptic membrane|,response to ischemia|apoptotic process|cerebellum development|cerebellar Purkinje cell layer development|cerebellar granular layer development|cerebellar Purkinje cell differentiation|regulation of neuron apoptotic process|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|negative regulation of apoptotic signaling pathway|,molecular_function|,9,0,0,9,0.1,0.173,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000026770,IL2RA,"interleukin 2 receptor, alpha chain",external side of plasma membrane|cell surface|membrane|integral component of membrane|,inflammatory response to antigenic stimulus|activation-induced cell death of T cells|Notch signaling pathway|interleukin-2-mediated signaling pathway|positive regulation of T cell proliferation|positive regulation of activated T cell proliferation|negative regulation of T cell proliferation|T cell homeostasis|positive regulation of T cell differentiation|regulation of T cell homeostatic proliferation|negative regulation of lymphocyte proliferation|negative regulation of defense response to virus|negative regulation of inflammatory response|negative regulation of immune response|,interleukin-2 receptor activity|interleukin-2 receptor activity|protein binding|drug binding|interleukin-2 binding|,10,0.3,0.0079,10,0,0,0,0,0,0.871,0,0,-1,2
ENSMUSG00000030494,RHPN2,"rhophilin, Rho GTPase binding protein 2",nucleus|cytoplasm|intracellular membrane-bounded organelle|,signal transduction|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1,2
ENSMUSG00000019256,AHR,aryl-hydrocarbon receptor,nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytosol|cytosol|aryl hydrocarbon receptor complex|cytosolic aryl hydrocarbon receptor complex|nuclear aryl hydrocarbon receptor complex|,"negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|ovarian follicle development|blood vessel development|patterning of blood vessels|B cell homeostasis|B cell homeostasis|liver development|B-1 B cell homeostasis|blood vessel remodeling|lymphocyte homeostasis|lymphocyte homeostasis|immune system process|negative regulation of systemic arterial blood pressure|cardiac left ventricle morphogenesis|circumferential growth involved in left ventricle morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|xenobiotic metabolic process|response to stress|response to stress|cell cycle|signal transduction|blood circulation|regulation of blood pressure|response to xenobiotic stimulus|response to xenobiotic stimulus|response to toxic substance|regulation of gene expression|response to organic cyclic compound|B cell differentiation|intracellular receptor signaling pathway|intracellular receptor signaling pathway|prostate gland development|regulation of B cell proliferation|circadian regulation of gene expression|embryonic hemopoiesis|post-embryonic hemopoiesis|camera-type eye development|T cell homeostasis|positive regulation of cell size|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of vasoconstriction|positive regulation of growth|blood vessel morphogenesis|spleen development|reproductive structure development|gland development|smooth muscle tissue development|regulation of blood vessel size|regulation of heart growth|negative regulation of necrotic cell death|venous blood vessel development|kidney morphogenesis|common bile duct development|cellular response to cAMP|glomerulus morphogenesis|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|signal transducer activity|aryl hydrocarbon receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|transcription factor binding|enhancer binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|Hsp90 protein binding|Hsp90 protein binding|E-box binding|,10,0,0,10,-0.2,0.868,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000021055,ESR2,estrogen receptor 2 (beta),nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|plasma membrane|neuron projection|neuronal cell body|perikaryon|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|ovarian follicle development|behavioral fear response|neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|brain development|learning or memory|negative regulation of cell proliferation|hormone-mediated apoptotic signaling pathway|intracellular steroid hormone receptor signaling pathway|intracellular estrogen receptor signaling pathway|response to testosterone|regulation of cell proliferation|positive regulation of apoptotic process|steroid hormone mediated signaling pathway|regulation of neuron apoptotic process|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of behavior|negative regulation of smooth muscle cell proliferation|negative regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|positive regulation of sequence-specific DNA binding transcription factor activity|Sertoli cell proliferation|uterus development|vagina development|negative regulation of cell death|prostate gland epithelium morphogenesis|epithelial cell maturation involved in prostate gland development|negative regulation of androgen receptor signaling pathway|positive regulation of ERK1 and ERK2 cascade|negative regulation of neuron death|negative regulation of reactive oxygen species metabolic process|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|steroid binding|protein binding|zinc ion binding|lipid binding|enzyme binding|estrogen receptor activity|estrogen response element binding|hormone binding|peroxisome proliferator activated receptor binding|sequence-specific DNA binding|metal ion binding|,10,-0.1,0.181,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000004018,FANCL,"Fanconi anemia, complementation group L",nucleus|nuclear envelope|cytoplasm|Fanconi anaemia nuclear complex|,DNA repair|protein monoubiquitination|cellular response to DNA damage stimulus|gamete generation|protein ubiquitination|regulation of cell proliferation|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000024308,TAPBP,TAP binding protein,Golgi membrane|endoplasmic reticulum|endoplasmic reticulum membrane|integral component of plasma membrane|membrane|integral component of membrane|MHC class I peptide loading complex|TAP complex|,"antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent|defense response|antigen processing and presentation of endogenous peptide antigen via MHC class I|peptide antigen stabilization|",protein binding|TAP1 binding|TAP2 binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000038546,RANBP9,RAN binding protein 9,nucleus|nucleus|cytoplasm|cytoplasm|,None,protein binding|Ran GTPase binding|enzyme binding|,10,-0.1,0.314,10,0.2,0.693,0,0,0,0.871,0,0,-1.3,1.6
ENSMUSG00000048349,POU4F1,"POU domain, class 4, transcription factor 1",nuclear chromatin|nucleus|neuron projection|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|suckling behavior|ventricular compact myocardium morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|mesoderm development|cell migration in hindbrain|trigeminal nerve development|central nervous system neuron differentiation|habenula development|neuron differentiation|positive regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|neuron fate specification|sensory system development|peripheral nervous system neuron differentiation|peripheral nervous system neuron development|peripheral nervous system neuron development|regulation of neurogenesis|proprioception involved in equilibrioception|innervation|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,9,0,0,9,0,0,0,0,0,0.871,0,0,-1.5,1.7
ENSMUSG00000037358,4930578C19RIK,RIKEN cDNA 4930578C19 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000030865,CHP2,calcineurin-like EF hand protein 2,nucleus|cytoplasm|plasma membrane|membrane|,transport|sodium ion transport|regulation of pH|positive regulation of cell proliferation|positive regulation of phosphatase activity|protein transport|positive regulation of protein import into nucleus|positive regulation of transcription from RNA polymerase II promoter|positive regulation of calcineurin-NFAT signaling cascade|cellular response to calcium ion|,calcium ion binding|metal ion binding|,10,0.2,0.509,10,-1,1.56,0,0,0,0.871,0,0,-2,1
ENSMUSG00000049119,FAM110B,"family with sequence similarity 110, member B",cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000054793,CADM4,cell adhesion molecule 4,membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|,None,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000027965,OLFM3,olfactomedin 3,extracellular region|extracellular space|Golgi apparatus|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|,eye photoreceptor cell development|,protein binding|,10,0,0,10,-0.2,0.534,0,0,0,0.871,0,0,-1.5,1.4
ENSMUSG00000038668,LPAR1,lysophosphatidic acid receptor 1,cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|endocytic vesicle|dendritic spine|dendritic shaft|,activation of MAPK activity|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cell death|negative regulation of neuron projection development|bleb assembly|positive regulation of Rho protein signal transduction|positive regulation of apoptotic process|positive regulation of MAPK cascade|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|positive regulation of dendritic spine development|positive regulation of smooth muscle cell chemotaxis|,G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|protein binding|phospholipid binding|PDZ domain binding|lysophosphatidic acid receptor activity|,10,0,0,10,-0.4,0.832,0,0,0,0.871,0,0,-1.9,0.9
ENSMUSG00000022146,OSMR,oncostatin M receptor,integral component of plasma membrane|oncostatin-M receptor complex|membrane|integral component of membrane|,cell surface receptor signaling pathway|positive regulation of cell proliferation|response to cytokine|oncostatin-M-mediated signaling pathway|oncostatin-M-mediated signaling pathway|,cytokine receptor activity|oncostatin-M receptor activity|oncostatin-M receptor activity|growth factor binding|,10,0.2,0.665,10,0,0,0,0,0,0.871,0,0,-1.2,1.7
ENSMUSG00000031227,MAGEE1,"melanoma antigen, family E, 1",nucleus|cytoplasm|plasma membrane|dystrophin-associated glycoprotein complex|membrane|dendrite|postsynaptic membrane|perinuclear region of cytoplasm|,biological_process|,protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000070637,GM694,predicted gene 694,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000009733,TFCP2,transcription factor CP2,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",DNA binding|,10,0.6,0.796,10,-0.5,0.383,0,0,0,0.871,0,0,-1.3,1.8
ENSMUSG00000055745,LDOC1L,"leucine zipper, down-regulated in cancer 1-like",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0569,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000025318,JPH3,junctophilin 3,endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|membrane|integral component of membrane|junctional membrane complex|,learning|memory|exploration behavior|locomotion|regulation of neuronal synaptic plasticity|regulation of neuronal synaptic plasticity|neuromuscular process controlling balance|regulation of ryanodine-sensitive calcium-release channel activity|calcium ion transmembrane transport|,calcium-release channel activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000006270,VAX1,ventral anterior homeobox 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|negative regulation of neuroblast proliferation|axon guidance|central nervous system development|brain development|cell differentiation|skeletal muscle cell differentiation|camera-type eye development|palate development|",DNA binding|sequence-specific DNA binding transcription factor activity|chromatin DNA binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000076432,YWHAQ,"tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide",intracellular|cell|cytoplasm|membrane|protein complex|extracellular vesicular exosome|,"protein targeting|signal transduction|small GTPase mediated signal transduction|negative regulation of transcription, DNA-templated|oxidation-reduction process|",monooxygenase activity|protein binding|oxidoreductase activity|protein domain specific binding|protein N-terminus binding|14-3-3 protein binding|,10,0.1,0.385,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000067338,TUBA3B,"tubulin, alpha 3B",nucleus|,biological_process|,molecular_function|,10,0,0,10,0.3,0.854,0,0,0,0.871,0,0,-1.1,1.9
ENSMUSG00000026029,CASP8,caspase 8,nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|microtubule organizing center|cytosol|Noc1p-Noc2p complex|death-inducing signaling complex|CD95 death-inducing signaling complex|neuron projection|protein complex|cell body|membrane raft|ripoptosome|,angiogenesis|neural tube formation|proteolysis|proteolysis|apoptotic process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|heart development|extrinsic apoptotic signaling pathway via death domain receptors|macrophage differentiation|macrophage differentiation|response to tumor necrosis factor|TRAIL-activated apoptotic signaling pathway|regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|response to ethanol|positive regulation of macrophage differentiation|positive regulation of proteolysis|cardiac muscle tissue development|protein heterooligomerization|proteolysis involved in cellular protein catabolic process|negative regulation of necroptotic process|regulation of thymocyte apoptotic process|apoptotic signaling pathway|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway|execution phase of apoptosis|activation of cysteine-type endopeptidase activity|hepatocyte apoptotic process|regulation of apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|,endopeptidase activity|endopeptidase activity|cysteine-type endopeptidase activity|cysteine-type endopeptidase activity|cysteine-type endopeptidase activity|death receptor binding|tumor necrosis factor receptor binding|protein binding|peptidase activity|peptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitin protein ligase binding|protein complex binding|death effector domain binding|death effector domain binding|protein heterodimerization activity|scaffold protein binding|cysteine-type endopeptidase activity involved in apoptotic process|cysteine-type endopeptidase activity involved in apoptotic process|cysteine-type endopeptidase activity involved in apoptotic signaling pathway|,9,0,0,9,0,0,0,0,0,0.871,0,0,-2,0.9
ENSMUSG00000020954,STRN3,"striatin, calmodulin binding protein 3",protein phosphatase type 2A complex|nucleus|nucleoplasm|cytoplasm|Golgi apparatus|plasma membrane|membrane|dendrite|neuronal cell body|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|response to estradiol|negative regulation of intracellular estrogen receptor signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",sequence-specific DNA binding transcription factor activity|calmodulin binding|protein complex binding|protein phosphatase 2A binding|armadillo repeat domain binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000032766,GNG11,"guanine nucleotide binding protein (G protein), gamma 11",heterotrimeric G-protein complex|plasma membrane|membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|,9,0.7,0.34,9,-0.1,0.339,0,0,0,0.871,0,0,-1,2
ENSMUSG00000074743,THBD,thrombomodulin,extracellular space|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|,female pregnancy|blood coagulation|hemostasis|embryo development|negative regulation of coagulation|,transmembrane signaling receptor activity|calcium ion binding|carbohydrate binding|,10,0.1,0.233,10,0,0,0,0,0,0.871,0,0,-1.8,1.3
ENSMUSG00000024421,LAMA3,"laminin, alpha 3",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|laminin-1 complex|laminin-3 complex|laminin-5 complex|cell-cell adherens junction|hemidesmosome|,cell adhesion|single organismal cell-cell adhesion|regulation of cell adhesion|regulation of cell migration|hemidesmosome assembly|regulation of embryonic development|,receptor binding|,10,0,0,10,0.1,0.0118,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000040093,BMF,BCL2 modifying factor,acrosomal vesicle|cytoplasm|actin cytoskeleton|myosin complex|myosin complex|,apoptotic process|positive regulation of protein homooligomerization|anoikis|positive regulation of release of cytochrome c from mitochondria|negative regulation of apoptotic signaling pathway|positive regulation of apoptotic signaling pathway|,protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.7
ENSMUSG00000029671,WNT16,"wingless-type MMTV integration site family, member 16",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|cytoplasm|,multicellular organismal development|positive regulation of gene expression|positive regulation of phosphatidylinositol 3-kinase signaling|Wnt signaling pathway|neuron differentiation|keratinocyte differentiation|keratinocyte proliferation|cell fate commitment|positive regulation of JNK cascade|bone remodeling|cardiac epithelial to mesenchymal transition|negative regulation of cell death|replicative senescence|oxidative stress-induced premature senescence|,receptor binding|frizzled binding|,10,-0.5,1.31,10,0,0,0,0,0,0.871,0,0,-2,0.7
ENSMUSG00000031974,ABCB10,"ATP-binding cassette, sub-family B (MDR/TAP), member 10",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial membrane|,ATP catabolic process|transport|transmembrane transport|,"nucleotide binding|transporter activity|protein binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|protein homodimerization activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000062380,TUBB3,"tubulin, beta 3 class III",intracellular|nucleus|cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|axon|neuronal cell body|protein complex|cell periphery|,GTP catabolic process|microtubule-based process|mitotic nuclear division|axon guidance|axon guidance|neuron differentiation|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|protein binding|GTP binding|peptide binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000042622,MAFF,"v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)",nucleus|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle cell differentiation|regulation of epidermal cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,-0.1,0.651,0,0,0,0.871,0,0,-1.6,1.3
ENSMUSG00000025089,GFRA1,glial cell line derived neurotrophic factor family receptor alpha 1,extracellular space|plasma membrane|external side of plasma membrane|membrane|extrinsic component of membrane|axon|anchored component of membrane|neuronal cell body|receptor complex|extracellular vesicular exosome|,transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|anatomical structure morphogenesis|cell migration|neuron differentiation|neuron projection development|,receptor activity|receptor activity|integrin binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000026043,COL3A1,"collagen, type III, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type III trimer|collagen type III trimer|extracellular space|extracellular matrix|extracellular matrix|,blood vessel development|cell-matrix adhesion|transforming growth factor beta receptor signaling pathway|integrin-mediated signaling pathway|heart development|response to radiation|peptide cross-linking|cerebral cortex development|collagen fibril organization|collagen fibril organization|response to cytokine|positive regulation of Rho protein signal transduction|wound healing|extracellular fibril organization|skin development|digestive tract development|negative regulation of immune response|aorta smooth muscle tissue morphogenesis|cellular response to amino acid stimulus|negative regulation of neuron migration|,integrin binding|extracellular matrix structural constituent|SMAD binding|metal ion binding|platelet-derived growth factor binding|,10,-0.1,0.0273,10,0.4,1.23,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000059970,HSPA2,heat shock protein 2,synaptonemal complex|male germ cell nucleus|nucleus|mitochondrion|cytosol|cell surface|membrane|CatSper complex|extracellular vesicular exosome|blood microparticle|,positive regulation of protein phosphorylation|response to stress|male meiosis|male meiosis I|spermatid development|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle|protein refolding|synaptonemal complex disassembly|negative regulation of inclusion body assembly|,nucleotide binding|protein binding|ATP binding|enzyme binding|unfolded protein binding|glycolipid binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000031383,DUSP9,dual specificity phosphatase 9,cytoplasm|,inactivation of MAPK activity|protein dephosphorylation|phosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|kinase activity|transferase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-2,1
ENSMUSG00000079418,ATG4A,"autophagy related 4A, cysteine peptidase",None,proteolysis|,cysteine-type peptidase activity|,10,-0.5,0.486,10,0,0,0,0,0,0.871,0,0,-1.9,1
ENSMUSG00000066755,TNFSF18,"tumor necrosis factor (ligand) superfamily, member 18",extracellular space|plasma membrane|cell surface|membrane|integral component of membrane|,T cell proliferation involved in immune response|immune system process|immune response|tumor necrosis factor-mediated signaling pathway|regulation of T cell proliferation|positive regulation of NF-kappaB transcription factor activity|,cytokine activity|tumor necrosis factor receptor binding|protein binding|tumor necrosis factor receptor superfamily binding|,10,-0.7,0.896,10,-0.1,0.0135,0,0,0,0.871,0,0,-2,0.6
ENSMUSG00000048776,PTHLH,parathyroid hormone-like peptide,extracellular region|extracellular space|intracellular|nucleus|cytoplasm|Golgi apparatus|,skeletal system development|skeletal system development|endochondral ossification|osteoblast development|adenylate cyclase-activating G-protein coupled receptor signaling pathway|endoderm development|positive regulation of cell proliferation|regulation of gene expression|protein processing|positive regulation of cAMP biosynthetic process|epithelial cell differentiation|regulation of chondrocyte differentiation|negative regulation of chondrocyte differentiation|negative regulation of chondrocyte differentiation|negative regulation of chondrocyte differentiation|negative regulation of chondrocyte differentiation|surfactant homeostasis|negative regulation of sequence-specific DNA binding transcription factor activity|lung alveolus development|mammary gland bud elongation|nipple sheath formation|,hormone activity|hormone activity|peptide hormone receptor binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000023008,FMNL3,formin-like 3,cytoplasm|,cytoskeleton organization|regulation of cell shape|cellular component organization|cell migration|actin cytoskeleton organization|,actin binding|protein binding|Rho GTPase binding|GTPase activating protein binding|,10,0.3,1.22,10,-0.2,0.13,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000038268,OVCA2,candidate tumor suppressor in ovarian cancer 2,nucleus|cytoplasm|cytoplasm|,response to retinoic acid|,molecular_function|,9,0,0,9,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000005836,GATA6,GATA binding protein 6,nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|liver development|outflow tract septum morphogenesis|type B pancreatic cell differentiation|pancreatic A cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|phospholipid metabolic process|endodermal cell fate determination|regulation of gene expression|cardiac muscle hypertrophy in response to stress|positive regulation of BMP signaling pathway|epithelial cell differentiation|pancreas development|negative regulation of transforming growth factor beta1 production|negative regulation of transforming growth factor beta2 production|tube morphogenesis|endodermal cell differentiation|response to drug|positive regulation of apoptotic process|negative regulation of apoptotic process|response to estrogen|positive regulation of angiogenesis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|organ formation|cardiac muscle tissue development|smooth muscle cell differentiation|cardiac muscle cell differentiation|cardiac muscle cell differentiation|positive regulation of cardiac muscle cell proliferation|lung saccule development|Clara cell differentiation|Type II pneumocyte differentiation|intestinal epithelial cell differentiation|cardiac vascular smooth muscle cell differentiation|response to growth factor|positive regulation of cell cycle arrest|cellular response to gonadotropin stimulus|cellular response to hypoxia|cellular response to BMP stimulus|",RNA polymerase II core promoter sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II repressing transcription factor binding|enhancer sequence-specific DNA binding|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|transcription factor binding|zinc ion binding|protein kinase binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,0.2,0.464,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000003541,IER3,immediate early response 3,nucleus|nucleus|membrane|integral component of membrane|,response to protozoan|negative regulation of systemic arterial blood pressure|regulation of DNA repair|mitotic G2 DNA damage checkpoint|intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of apoptotic process|positive regulation of protein catabolic process|negative regulation of glycolytic process|regulation of nucleocytoplasmic transport|negative regulation of inflammatory response|negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|regulation of reactive oxygen species metabolic process|regulation of response to DNA damage stimulus|regulation of response to DNA damage stimulus|,protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000066687,ZBTB16,zinc finger and BTB domain containing 16,nucleus|nucleus|cytosol|plasma membrane|nuclear body|PML body|nuclear speck|nuclear speck|transcriptional repressor complex|,"skeletal system development|mesonephros development|regulation of transcription, DNA-templated|central nervous system development|negative regulation of cell proliferation|embryonic pattern specification|anterior/posterior pattern specification|hemopoiesis|hemopoiesis|embryonic limb morphogenesis|positive regulation of chondrocyte differentiation|protein localization to nucleus|embryonic hindlimb morphogenesis|embryonic hindlimb morphogenesis|forelimb morphogenesis|hindlimb morphogenesis|embryonic digit morphogenesis|positive regulation of apoptotic process|positive regulation of fat cell differentiation|negative regulation of myeloid cell differentiation|positive regulation of ossification|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|male germ-line stem cell asymmetric division|positive regulation of NK T cell differentiation|cartilage development|positive regulation of cartilage development|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein C-terminus binding|protein domain specific binding|identical protein binding|protein homodimerization activity|metal ion binding|,10,-0.1,0.16,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000025907,RB1CC1,RB1-inducible coiled-coil 1,pre-autophagosomal structure|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|nuclear membrane|pre-autophagosomal structure membrane|ULK1-ATG13-FIP200 complex|ULK1-ATG13-FIP200 complex|,"autophagic vacuole assembly|liver development|positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|autophagy|cell cycle|JNK cascade|heart development|regulation of autophagy|negative regulation of apoptotic process|positive regulation of cell size|negative regulation of extrinsic apoptotic signaling pathway|",protein binding|protein kinase binding|,10,0.1,0.0667,10,0,0,0,0,0,0.871,0,0,-1.4,1.5
ENSMUSG00000068327,TLX2,"T cell leukemia, homeobox 2",nucleus|nucleus|cytoplasm|,"mesoderm formation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|enteric nervous system development|negative regulation of dendrite morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000000305,CDH4,cadherin 4,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|axon guidance|positive regulation of axon extension|,calcium ion binding|metal ion binding|,10,0,0,10,0.3,0.729,0,0,0,0.871,0,0,-1.1,1.7
ENSMUSG00000020170,FRS2,fibroblast growth factor receptor substrate 2,cytoplasm|plasma membrane|cell-cell junction|membrane|,"activation of MAPK activity|gastrulation with mouth forming second|organ induction|lens development in camera-type eye|ventricular septum development|transmembrane receptor protein tyrosine kinase signaling pathway|neuroblast proliferation|neuroblast proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|anterior/posterior axis specification, embryo|positive regulation of signal transduction|forebrain development|regulation of apoptotic process|optic placode formation involved in camera-type eye formation|regulation of epithelial cell proliferation|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis|lens fiber cell development|lens fiber cell development|regulation of ERK1 and ERK2 cascade|",transmembrane receptor protein tyrosine kinase adaptor activity|fibroblast growth factor receptor binding|insulin receptor binding|neurotrophin TRKA receptor binding|protein binding|,10,-0.5,0.398,10,0,0,0,0,0,0.871,0,0,-2,0.8
ENSMUSG00000001870,LTBP1,latent transforming growth factor beta binding protein 1,extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular matrix|,transforming growth factor beta receptor signaling pathway|,calcium ion binding|growth factor binding|transforming growth factor beta binding|,10,0,0,10,0.1,0.078,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000041120,NBL1,"neuroblastoma, suppression of tumorigenicity 1",extracellular region|,nervous system development|negative regulation of BMP signaling pathway|sequestering of BMP in extracellular matrix|positive regulation of neuron differentiation|determination of dorsal identity|neuron projection morphogenesis|negative regulation of monocyte chemotaxis|,protein binding|morphogen activity|BMP binding|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000079465,COL4A3,"collagen, type IV, alpha 3",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type IV trimer|collagen type IV trimer|basement membrane|basement membrane|,activation of cysteine-type endopeptidase activity involved in apoptotic process|cell adhesion|cell surface receptor signaling pathway|cell proliferation|negative regulation of angiogenesis|negative regulation of angiogenesis|glomerular basement membrane development|endothelial cell apoptotic process|,integrin binding|extracellular matrix structural constituent|,10,-0.1,0.379,10,0,0,0,0,0,0.871,0,0,-1.9,1.1
ENSMUSG00000019718,L3HYPDH,L-3-hydroxyproline dehydratase (trans-),cellular_component|,metabolic process|metabolic process|,lyase activity|hydro-lyase activity|hydro-lyase activity|trans-L-3-hydroxyproline dehydratase activity|,10,0,0,10,0.2,0.602,0,0,0,0.871,0,0,-1.1,1.8
ENSMUSG00000034111,TMED8,transmembrane emp24 domain containing 8,cellular_component|integral component of membrane|,transport|biological_process|,molecular_function|,10,0,0,10,0.1,0.302,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000028955,VAMP3,vesicle-associated membrane protein 3,intracellular|cell|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|cell junction|clathrin-coated vesicle|secretory granule|clathrin-coated vesicle membrane|SNARE complex|cytoplasmic vesicle|neuron projection|intracellular organelle|intracellular membrane-bounded organelle|synapse|recycling endosome|,"positive regulation of receptor recycling|protein complex assembly|transport|protein transport|vesicle-mediated transport|calcium ion-dependent exocytosis|substrate adhesion-dependent cell spreading|SNARE complex assembly|retrograde transport, endosome to Golgi|Golgi to plasma membrane protein transport|",SNARE binding|protein binding|syntaxin-1 binding|,10,0,0,10,0.2,0.0903,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000004347,PDE1C,phosphodiesterase 1C,cilium|neuronal cell body|,cAMP catabolic process|signal transduction|sensory perception of smell|sensory perception of smell|cGMP catabolic process|negative regulation of insulin secretion|response to calcium ion|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|calmodulin binding|phosphoric diester hydrolase activity|hydrolase activity|cAMP binding|metal ion binding|calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity|",10,0,0,10,0.3,0.574,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000032528,VIPR1,vasoactive intestinal peptide receptor 1,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|vasoactive intestinal polypeptide receptor activity|,10,0.6,0.0151,10,0.2,0.309,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000028458,TESK1,testis specific protein kinase 1,None,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.3,0.241,10,0,0,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000072575,EDDM3B,epididymal protein 3B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000030043,TACR1,tachykinin receptor 1,cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|dendrite|cell body|cell periphery|,"aggressive behavior|positive regulation of leukocyte migration|angiotensin-mediated drinking behavior|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|tachykinin receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|learning or memory|long-term memory|regulation of blood pressure|associative learning|response to heat|response to hormone|response to ozone|positive regulation of epithelial cell migration|response to auditory stimulus|response to organic cyclic compound|regulation of smooth muscle cell migration|sensory perception of pain|positive regulation of synaptic transmission, cholinergic|positive regulation of synaptic transmission, GABAergic|response to nicotine|operant conditioning|positive regulation of renal sodium excretion|sperm ejaculation|eating behavior|positive regulation of vascular permeability|response to ethanol|positive regulation of action potential|positive regulation of blood pressure|positive regulation of ossification|positive regulation of vasoconstriction|positive regulation of saliva secretion|positive regulation of hormone secretion|response to pain|behavioral response to pain|regulation of smooth muscle cell proliferation|positive regulation of lymphocyte proliferation|positive regulation of epithelial cell proliferation|positive regulation of stress fiber assembly|smooth muscle contraction involved in micturition|positive regulation of uterine smooth muscle contraction|",signal transducer activity|G-protein coupled receptor activity|tachykinin receptor activity|substance P receptor activity|,10,0,0,10,-0.3,0.0977,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000021453,GADD45G,growth arrest and DNA-damage-inducible 45 gamma,nucleus|nucleus|cytoplasm|,activation of MAPKKK activity|activation of MAPKK activity|negative regulation of protein kinase activity|apoptotic process|response to stress|multicellular organismal development|cell differentiation|interferon-gamma biosynthetic process|positive regulation of apoptotic process|T-helper 1 cell differentiation|positive regulation of JNK cascade|regulation of cell cycle|positive regulation of p38MAPK cascade|,protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000013415,IGF2BP1,insulin-like growth factor 2 mRNA binding protein 1,nucleus|cytoplasm|cytoplasmic stress granule|dendrite|ribonucleoprotein complex|cell projection|CRD-mediated mRNA stability complex|,RNA localization|regulation of translation|transport|regulation of mRNA stability involved in response to stress|negative regulation of translation|mRNA transport|CRD-mediated mRNA stabilization|,nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|mRNA 3'-UTR binding|poly(A) RNA binding|translation regulator activity|mRNA 5'-UTR binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000092243,GM7030,predicted gene 7030,None,None,None,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000020836,CORO6,coronin 6,actin cytoskeleton|,actin cytoskeleton organization|,actin filament binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000035158,MITF,microphthalmia-associated transcription factor,nucleus|nucleus|protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein complex assembly|multicellular organismal development|regulation of gene expression|Wnt signaling pathway|cell differentiation|osteoclast differentiation|melanocyte differentiation|melanocyte differentiation|regulation of cell proliferation|camera-type eye development|negative regulation of apoptotic process|pigmentation|pigmentation|canonical Wnt signaling pathway involved in negative regulation of apoptotic process|cell fate commitment|regulation of osteoclast differentiation|regulation of osteoclast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|bone remodeling|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|protein dimerization activity|,10,0,0,10,-0.1,0.238,0,0,0,0.871,0,0,-2,0.9
ENSMUSG00000048782,INSC,inscuteable homolog (Drosophila),cell|cytoplasm|apical part of cell|,establishment of mitotic spindle orientation|multicellular organismal development|nervous system development|cell differentiation|lung epithelial cell differentiation|,None,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000038600,ATP6V0A4,"ATPase, H+ transporting, lysosomal V0 subunit A4","vacuolar proton-transporting V-type ATPase, V0 domain|lysosomal membrane|endosome|plasma membrane|brush border|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|vacuolar proton-transporting V-type ATPase complex|vacuolar proton-transporting V-type ATPase complex|vacuolar proton-transporting V-type ATPase complex|brush border membrane|proton-transporting V-type ATPase, V0 domain|apical part of cell|apical part of cell|extracellular vesicular exosome|",ossification|ATP catabolic process|transport|ion transport|regulation of pH|excretion|sensory perception of sound|ATP hydrolysis coupled proton transport|ATP hydrolysis coupled proton transport|proton transport|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrogen ion transmembrane transporter activity|ATPase binding|",10,-0.3,0.535,10,0.9,0.169,0,0,0,0.871,0,0,-1.1,2
ENSMUSG00000029570,LFNG,LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,ovarian follicle development|somitogenesis|female meiotic division|multicellular organismal development|compartment pattern specification|pattern specification process|regulation of Notch signaling pathway|regulation of somitogenesis|regulation of somitogenesis|positive regulation of protein binding|positive regulation of Notch signaling pathway|,"transferase activity|transferase activity, transferring glycosyl groups|O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity|metal ion binding|",10,0.1,0.339,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000029287,TGFBR3,"transforming growth factor, beta receptor III",extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|cytoplasm|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|inhibin-betaglycan-ActRII complex|extracellular vesicular exosome|,blood vessel development|in utero embryonic development|blastocyst development|epithelial to mesenchymal transition|liver development|epicardial cell to mesenchymal cell transition|protein complex assembly|protein phosphorylation|immune response|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor complex assembly|embryo development|negative regulation of epithelial cell migration|negative regulation of epithelial to mesenchymal transition|cell growth|BMP signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|response to follicle-stimulating hormone|response to prostaglandin E|response to luteinizing hormone|intracellular signal transduction|regulation of protein binding|negative regulation of epithelial cell proliferation|regulation of blood vessel size|positive regulation of NF-kappaB transcription factor activity|negative regulation of cellular component movement|ventricular cardiac muscle tissue morphogenesis|palate development|cardiac muscle cell proliferation|definitive hemopoiesis|cardiac epithelial to mesenchymal transition|definitive erythrocyte differentiation|heart trabecula formation|pathway-restricted SMAD protein phosphorylation|pathway-restricted SMAD protein phosphorylation|coronary vasculature development|coronary vasculature morphogenesis|vasculogenesis involved in coronary vascular morphogenesis|visceral serous pericardium development|,"transforming growth factor beta-activated receptor activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta-activated receptor activity|type II transforming growth factor beta receptor binding|transforming growth factor beta receptor binding|protein binding|glycosaminoglycan binding|heparin binding|coreceptor activity|fibroblast growth factor binding|PDZ domain binding|SMAD binding|SMAD binding|activin binding|transforming growth factor beta binding|transforming growth factor beta binding|transforming growth factor beta receptor activity, type III|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000007867,IFT43,intraflagellar transport 43,intracellular|cell|cytoplasm|microtubule organizing center|cytoskeleton|cilium|microtubule cytoskeleton|intraciliary transport particle A|intraciliary transport particle A|,cell projection organization|intraciliary retrograde transport|intraciliary retrograde transport|cilium morphogenesis|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000020333,ACSL6,acyl-CoA synthetase long-chain family member 6,nucleus|mitochondrion|mitochondrial outer membrane|peroxisome|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|triglyceride metabolic process|neuroblast proliferation|metabolic process|phospholipid biosynthetic process|positive regulation of plasma membrane long-chain fatty acid transport|positive regulation of triglyceride biosynthetic process|positive regulation of neuron projection development|fatty acid transport|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|protein binding|ATP binding|ligase activity|enzyme binding|protein homodimerization activity|,10,0,0,10,0.4,0.476,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000032281,ACSBG1,acyl-CoA synthetase bubblegum family member 1,cytoplasm|cytoplasmic vesicle|intracellular membrane-bounded organelle|,very long-chain fatty acid metabolic process|very long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|metabolic process|response to glucocorticoid|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|ATP binding|ligase activity|very long-chain fatty acid-CoA ligase activity|very long-chain fatty acid-CoA ligase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000053334,FICD,FIC domain containing,cellular_component|membrane|integral component of membrane|,protein adenylylation|,nucleotide binding|ATP binding|transferase activity|nucleotidyltransferase activity|protein adenylyltransferase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000027635,DSN1,"DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)","MIS12/MIND type complex|chromosome, centromeric region|kinetochore|nucleus|chromosome|",cell cycle|chromosome segregation|mitotic nuclear division|biological_process|cell division|,molecular_function|,10,0,0,10,-0.1,0.0252,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000011171,VIPR2,vasoactive intestinal peptide receptor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|negative regulation of smooth muscle cell proliferation|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|vasoactive intestinal polypeptide receptor activity|,10,0.7,0.863,10,0,0,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000004098,COL5A3,"collagen, type V, alpha 3",collagen trimer|collagen type V trimer|collagen type V trimer|extracellular matrix|extracellular vesicular exosome|,cell-matrix adhesion|extracellular matrix organization|,structural molecule activity|heparin binding|proteoglycan binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000000125,WNT3,"wingless-type MMTV integration site family, member 3",extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|extracellular matrix|,cell morphogenesis|mesoderm formation|signal transduction|cell-cell signaling|multicellular organismal development|gamete generation|axon guidance|organ morphogenesis|anterior/posterior axis specification|dorsal/ventral axis specification|anterior/posterior pattern specification|positive regulation of gene expression|Wnt signaling pathway|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt signaling pathway involved in osteoblast differentiation|anatomical structure formation involved in morphogenesis|positive regulation of collateral sprouting in absence of injury|negative regulation of axon extension involved in axon guidance|Spemann organizer formation at the anterior end of the primitive streak|canonical Wnt signaling pathway|canonical Wnt signaling pathway|limb development|limb bud formation|head morphogenesis|,receptor binding|frizzled binding|frizzled binding|protein binding|protein domain specific binding|,10,-0.6,0.289,10,-0.1,0.351,0,0,0,0.871,0,0,-2,0.7
ENSMUSG00000089984,FBXO24,F-box protein 24,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.837,0,0,0,0.871,0,0,-1.6,1.3
ENSMUSG00000002799,JAG2,jagged 2,integral component of plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,skeletal system development|in utero embryonic development|cell fate determination|respiratory system process|cell communication|Notch signaling pathway|multicellular organismal development|spermatogenesis|sensory perception of sound|auditory receptor cell fate commitment|morphogenesis of embryonic epithelium|cell differentiation|regulation of cell adhesion|T cell differentiation|regulation of cell proliferation|regulation of cell proliferation|odontogenesis of dentin-containing tooth|gamma-delta T cell differentiation|thymic T cell selection|thymic T cell selection|epithelial cell apoptotic process involved in palatal shelf morphogenesis|,Notch binding|calcium ion binding|protein binding|growth factor activity|growth factor activity|,10,0.1,0.0658,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000039661,DUSP26,dual specificity phosphatase 26 (putative),nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|Golgi apparatus|extracellular vesicular exosome|,negative regulation of transcription from RNA polymerase II promoter|protein dephosphorylation|protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|negative regulation of protein kinase activity by regulation of protein phosphorylation|positive regulation of cell adhesion|negative regulation of ERK1 and ERK2 cascade|positive regulation of peptidyl-serine dephosphorylation|,RNA polymerase II activating transcription factor binding|p53 binding|phosphoserine phosphatase activity|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,0,0,10,-0.7,0.154,0,0,0,0.871,0,0,-2,0.9
ENSMUSG00000022475,HDAC7,histone deacetylase 7,histone deacetylase complex|nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|vasculogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|inflammatory response|cell-cell junction assembly|nervous system development|chromatin modification|histone deacetylation|B cell differentiation|negative regulation of interleukin-2 production|B cell activation|negative regulation of osteoblast differentiation|negative regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of cell migration involved in sprouting angiogenesis|",chromatin binding|transcription corepressor activity|histone deacetylase activity|protein kinase C binding|protein binding|transcription factor binding|hydrolase activity|protein kinase binding|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|activating transcription factor binding|histone deacetylase activity (H4-K16 specific)|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|repressing transcription factor binding|14-3-3 protein binding|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000008305,TLE1,"transducin-like enhancer of split 1, homolog of Drosophila E(spl)",nucleus|nucleus|transcription factor complex|nucleolus|cytoplasm|cytosol|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of gene expression|Wnt signaling pathway|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of transcription, DNA-templated|negative regulation of anoikis|",RNA polymerase II transcription corepressor activity|chromatin binding|transcription corepressor activity|protein binding|transcription factor binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.1,1.9
ENSMUSG00000026646,SUV39H2,suppressor of variegation 3-9 homolog 2 (Drosophila),"chromosome, centromeric region|chromatin|nucleus|chromosome|nuclear heterochromatin|","chromatin assembly or disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|chromatin modification|peptidyl-lysine methylation|cell differentiation|methylation|histone lysine methylation|histone lysine methylation|histone H3-K9 dimethylation|histone H3-K9 trimethylation|negative regulation of circadian rhythm|negative regulation of transcription, DNA-templated|rhythmic process|histone H3-K9 methylation|histone H3-K9 methylation|",transcription regulatory region sequence-specific DNA binding|chromatin binding|protein binding|methyltransferase activity|zinc ion binding|protein methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone-lysine N-methyltransferase activity|metal ion binding|histone methyltransferase activity (H3-K9 specific)|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000031538,PLAT,"plasminogen activator, tissue",extracellular region|extracellular space|extracellular space|cytoplasm|cytoplasm|cell surface|secretory granule|apical part of cell|synapse|extracellular vesicular exosome|,"response to hypoxia|proteolysis|proteolysis|smooth muscle cell migration|plasminogen activation|synaptic transmission, glutamatergic|negative regulation of proteolysis|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|positive regulation of ovulation|",catalytic activity|serine-type endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.3,0.245,0,0,0,0.871,0,0,-1,2
ENSMUSG00000022013,DNAJC15,"DnaJ (Hsp40) homolog, subfamily C, member 15",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,"transport|cellular response to starvation|protein transport|regulation of lipid metabolic process|negative regulation of protein complex assembly|negative regulation of mitochondrial electron transport, NADH to ubiquinone|",protein binding|,10,0.1,0.315,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000038256,BCL9,B cell CLL/lymphoma 9,nucleus|cytoplasm|Golgi apparatus|Golgi apparatus|cis-Golgi network|cis-Golgi network|,myotube differentiation involved in skeletal muscle regeneration|Wnt signaling pathway|somatic stem cell maintenance|skeletal muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter|canonical Wnt signaling pathway|,beta-catenin binding|,10,-0.4,1.85,10,0.2,0.583,0,0,0,0.871,0,0,-1.6,1.2
ENSMUSG00000028362,TNFSF8,"tumor necrosis factor (ligand) superfamily, member 8",extracellular space|membrane|integral component of membrane|,"immune response|CD8-positive, alpha-beta T cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|defense response to Gram-positive bacterium|",cytokine activity|tumor necrosis factor receptor binding|,10,0.1,0.527,10,-0.4,1.49,0,0,0,0.871,0,0,-1.8,1.1
ENSMUSG00000048240,GNG7,"guanine nucleotide binding protein (G protein), gamma 7",heterotrimeric G-protein complex|plasma membrane|membrane|extracellular vesicular exosome|,behavioral fear response|signal transduction|receptor guanylyl cyclase signaling pathway|G-protein coupled receptor signaling pathway|locomotory behavior|regulation of adenylate cyclase activity|,signal transducer activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000051335,GFOD1,glucose-fructose oxidoreductase domain containing 1,cellular_component|extracellular region|,biological_process|metabolic process|oxidation-reduction process|,N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000027656,WISP2,WNT1 inducible signaling pathway protein 2,extracellular region|extracellular space|cytoplasm|plasma membrane|cell surface|extracellular vesicular exosome|,regulation of cell growth|cell adhesion|negative regulation of cell proliferation|,insulin-like growth factor binding|growth factor activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000016520,LNX2,ligand of numb-protein X 2,cellular_component|,protein homooligomerization|,protein binding|zinc ion binding|PDZ domain binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000029207,APBB2,"amyloid beta (A4) precursor protein-binding, family B, member 2",nucleus|cytoplasm|,"neuron migration|regulation of transcription, DNA-templated|cell cycle arrest|axon guidance|actin filament-based movement|extracellular matrix organization|negative regulation of cell growth|positive regulation of apoptotic process|negative regulation of apoptotic process|protein stabilization|",protein binding|transcription factor binding|histone acetyltransferase binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000089762,IER5L,immediate early response 5-like,cellular_component|,biological_process|,molecular_function|,10,0.1,0.432,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000009741,UBP1,upstream binding protein 1,nucleus|,"angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-2,0.8
ENSMUSG00000060275,NRG2,neuregulin 2,None,epidermal growth factor receptor signaling pathway|peptidyl-tyrosine phosphorylation|,epidermal growth factor-activated receptor activity|epidermal growth factor receptor binding|ErbB-3 class receptor binding|,10,-0.4,0.88,10,0,0,0,0,0,0.871,0,0,-1.8,1
ENSMUSG00000049336,TENM2,teneurin transmembrane protein 2,intracellular|nucleus|endoplasmic reticulum|Golgi apparatus|plasma membrane|integral component of plasma membrane|cell-cell junction|membrane|integral component of membrane|cell junction|cell projection|neuron projection|dendritic spine|synapse|postsynaptic membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell adhesion|heterophilic cell-cell adhesion|signal transduction|axon guidance|calcium-mediated signaling using intracellular calcium source|self proteolysis|",receptor binding|protein homodimerization activity|protein heterodimerization activity|cell adhesion molecule binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.9,1.3
ENSMUSG00000059447,HADHB,"hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit",mitochondrion|mitochondrion|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial inner membrane|endoplasmic reticulum|membrane|mitochondrial fatty acid beta-oxidation multienzyme complex|mitochondrial fatty acid beta-oxidation multienzyme complex|mitochondrial nucleoid|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|fatty acid beta-oxidation|metabolic process|oxidation-reduction process|,"fatty-acyl-CoA binding|catalytic activity|3-hydroxyacyl-CoA dehydrogenase activity|acetyl-CoA C-acyltransferase activity|acetyl-CoA C-acyltransferase activity|acetyl-CoA C-acyltransferase activity|enoyl-CoA hydratase activity|long-chain-enoyl-CoA hydratase activity|long-chain-3-hydroxyacyl-CoA dehydrogenase activity|long-chain-3-hydroxyacyl-CoA dehydrogenase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|protein complex binding|poly(A) RNA binding|NAD binding|",10,0,0,10,-0.2,0.273,0,0,0,0.871,0,0,-1.5,1.8
ENSMUSG00000069036,SRY,sex determining region of Chr Y,nucleus|cytoplasm|nuclear transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|sex determination|sex differentiation|male gonad development|negative regulation of gene expression|cell differentiation|male sex determination|","sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|protein binding|calmodulin binding|DNA binding, bending|protein heterodimerization activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000029436,MMP17,matrix metallopeptidase 17,extracellular region|proteinaceous extracellular matrix|plasma membrane|membrane|extracellular matrix|anchored component of membrane|,proteolysis|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1,2
ENSMUSG00000032191,BCL2L10,Bcl2-like 10,nucleus|mitochondrion|mitochondrial outer membrane|cytosol|membrane|membrane|integral component of membrane|,apoptotic process|intrinsic apoptotic signaling pathway in response to DNA damage|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of intrinsic apoptotic signaling pathway|,protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000029385,CCNG2,cyclin G2,nucleus|cytoplasm|,cell cycle|mitotic nuclear division|cell division|regulation of cell cycle|,None,10,0.4,0.305,10,-0.1,0.155,0,0,0,0.871,0,0,-1,2
ENSMUSG00000022510,TRP63,transformation related protein 63,chromatin|nuclear chromatin|intracellular|nucleus|nucleus|nucleoplasm|transcription factor complex|cytoplasm|rough endoplasmic reticulum|cytosol|dendrite|dendrite|neuron projection|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|replicative cell aging|skeletal system development|establishment of planar polarity|morphogenesis of a polarized epithelium|hair follicle development|positive regulation of mesenchymal cell proliferation|epithelial cell development|epithelial cell development|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|apoptotic process|cellular response to DNA damage stimulus|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cell cycle|Notch signaling pathway|multicellular organismal development|pattern specification process|ectoderm and mesoderm interaction|cell aging|epidermis development|organ morphogenesis|proximal/distal pattern formation|response to X-ray|multicellular organismal aging|response to gamma radiation|epidermal cell division|regulation of epidermal cell division|positive regulation of keratinocyte proliferation|cell differentiation|keratinocyte differentiation|embryonic limb morphogenesis|embryonic limb morphogenesis|prostate gland development|epithelial cell differentiation|polarized epithelial cell differentiation|hair follicle morphogenesis|mitotic G1 DNA damage checkpoint|cellular response to UV|post-anal tail morphogenesis|odontogenesis of dentin-containing tooth|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of apoptotic process|regulation of neuron apoptotic process|skin morphogenesis|keratinocyte proliferation|negative regulation of keratinocyte differentiation|negative regulation of keratinocyte differentiation|positive regulation of osteoblast differentiation|positive regulation of Notch signaling pathway|positive regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|sympathetic nervous system development|anatomical structure formation involved in morphogenesis|smooth muscle tissue development|female genitalia morphogenesis|protein tetramerization|protein homotetramerization|neuron apoptotic process|urinary bladder development|cloacal septation|prostatic bud formation|squamous basal epithelial stem cell differentiation involved in prostate gland acinus development|establishment of skin barrier|positive regulation of cell cycle G1/S phase transition|positive regulation of fibroblast apoptotic process|negative regulation of mesoderm development|negative regulation of cellular senescence|regulation of RNA biosynthetic process|positive regulation of apoptotic signaling pathway|",transcription factor binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|p53 binding|DNA binding|chromatin binding|chromatin binding|damaged DNA binding|double-stranded DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein domain specific binding|identical protein binding|identical protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|WW domain binding|,10,-0.1,0.37,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000042129,RASSF4,Ras association (RalGDS/AF-6) domain family member 4,cellular_component|,cell cycle|signal transduction|,molecular_function|,10,0,0,10,0.2,0.694,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000022479,VDR,vitamin D receptor,euchromatin|heterochromatin|dense fibrillar component|nucleus|nuclear heterochromatin|cytosol|caveola|nuclear matrix|T-tubule|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|calcium ion transport|cellular calcium ion homeostasis|multicellular organismal development|lactation|negative regulation of cell proliferation|organ morphogenesis|positive regulation of gene expression|negative regulation of keratinocyte proliferation|positive regulation of vitamin D 24-hydroxylase activity|intracellular receptor signaling pathway|bile acid signaling pathway|steroid hormone mediated signaling pathway|positive regulation of keratinocyte differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|intestinal absorption|regulation of calcium ion transport|positive regulation of apoptotic process involved in mammary gland involution|regulation of calcidiol 1-monooxygenase activity|mammary gland branching involved in pregnancy|vitamin D receptor signaling pathway|apoptotic signaling pathway|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|vitamin D binding|protein binding|zinc ion binding|calcitriol receptor activity|lithocholic acid receptor activity|sequence-specific DNA binding|metal ion binding|retinoid X receptor binding|vitamin D response element binding|calcitriol binding|lithocholic acid binding|,10,0.2,0.435,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000052713,ZFP608,zinc finger protein 608,None,biological_process|,metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000026603,SMYD2,SET and MYND domain containing 2,nucleus|cytoplasm|cytosol|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cell proliferation|histone H3-K36 methylation|chromatin modification|histone methylation|peptidyl-lysine monomethylation|peptidyl-lysine dimethylation|methylation|regulation of DNA damage response, signal transduction by p53 class mediator|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA polymerase II core binding|p53 binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|histone methyltransferase activity (H3-K36 specific)|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.3,0.511,10,0,0,0,0,0,0.871,0,0,-0.9,1.9
ENSMUSG00000029468,P2RX7,"purinergic receptor P2X, ligand-gated ion channel, 7",intracellular|integral component of nuclear inner membrane|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cell-cell junction|external side of plasma membrane|membrane|membrane|integral component of membrane|neuromuscular junction|neuronal cell body|synapse|,activation of MAPK activity|cell morphogenesis|phagolysosome assembly|positive regulation of T cell mediated cytotoxicity|positive regulation of protein phosphorylation|protein phosphorylation|membrane protein ectodomain proteolysis|phospholipid transfer to membrane|transport|ion transport|cation transport|cation transport|calcium ion transport|cell volume homeostasis|membrane budding|inflammatory response|mitochondrion organization|plasma membrane organization|response to mechanical stimulus|response to bacterium|response to organic substance|response to zinc ion|gene expression|positive regulation of calcium ion transport into cytosol|programmed cell death|programmed cell death|positive regulation of glutamate secretion|positive regulation of gamma-aminobutyric acid secretion|response to organic cyclic compound|synaptic vesicle exocytosis|protein processing|sensory perception of pain|cytolysis|cytolysis|positive regulation of bone mineralization|cellular response to extracellular stimulus|bleb assembly|positive regulation of prostaglandin secretion|response to lipopolysaccharide|response to lipopolysaccharide|positive regulation of interleukin-1 beta production|positive regulation of interleukin-6 production|collagen metabolic process|response to ATP|response to ATP|response to ATP|ion transmembrane transport|response to fluid shear stress|purinergic nucleotide receptor signaling pathway|purinergic nucleotide receptor signaling pathway|T cell proliferation|response to drug|T cell homeostasis|positive regulation of apoptotic process|positive regulation of catalytic activity|NAD transport|negative regulation of MAPK cascade|positive regulation of MAPK cascade|multicellular organismal protein catabolic process|phospholipid translocation|positive regulation of ossification|negative regulation of bone resorption|ceramide biosynthetic process|pore complex assembly|pore complex assembly|skeletal system morphogenesis|homeostasis of number of cells within a tissue|positive regulation of protein secretion|positive regulation of cytokine secretion|positive regulation of interleukin-1 alpha secretion|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|defense response to Gram-positive bacterium|release of sequestered calcium ion into cytosol|protein oligomerization|response to calcium ion|response to calcium ion|response to electrical stimulus|membrane depolarization|positive regulation of mitochondrial depolarization|positive regulation of lymphocyte apoptotic process|reactive oxygen species metabolic process|extrinsic apoptotic signaling pathway|,lipopolysaccharide binding|purinergic nucleotide receptor activity|purinergic nucleotide receptor activity|receptor activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|ion channel activity|protein binding|ATP binding|channel activity|channel activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000024529,LOX,lysyl oxidase,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|collagen trimer|nucleus|,blood vessel development|response to hormone|collagen fibril organization|collagen fibril organization|lung development|wound healing|elastic fiber assembly|elastic fiber assembly|response to steroid hormone|oxidation-reduction process|,"protein-lysine 6-oxidase activity|protein-lysine 6-oxidase activity|copper ion binding|protein binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor|metal ion binding|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000029712,ACTL6B,actin-like 6B,nucleus|nucleolus|SWI/SNF complex|SWI/SNF complex|nBAF complex|,"chromatin assembly or disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|chromatin modification|",protein binding|,10,0,0,10,0.1,0.0209,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000068699,FLNC,"filamin C, gamma",cytoplasm|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|sarcoplasm|sarcolemma|,actin filament-based process|muscle fiber development|,actin binding|cytoskeletal protein binding|ankyrin binding|actin filament binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000001496,NKX2-1,NK2 homeobox 1,nucleus|nucleus|nucleoplasm|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|neuron migration|regulation of blood volume by renin-angiotensin|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|phospholipid metabolic process|pattern specification process|axon guidance|brain development|brain development|brain development|endoderm development|locomotory behavior|locomotory behavior|feeding behavior|organ morphogenesis|positive regulation of gene expression|negative regulation of epithelial to mesenchymal transition|telencephalon development|globus pallidus development|globus pallidus development|hippocampus development|cerebral cortex cell migration|forebrain dorsal/ventral pattern formation|forebrain neuron fate commitment|forebrain neuron fate commitment|forebrain neuron differentiation|cerebral cortex GABAergic interneuron differentiation|cerebral cortex neuron differentiation|cerebral cortex neuron differentiation|pituitary gland development|telencephalon cell migration|lung development|lung development|lung development|negative regulation of cell migration|negative regulation of transforming growth factor beta receptor signaling pathway|thyroid gland development|thyroid gland development|thyroid gland development|developmental induction|response to lipopolysaccharide|Leydig cell differentiation|hyperosmotic salinity response|menarche|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|anatomical structure formation involved in morphogenesis|neuron fate commitment|oligodendrocyte differentiation|lung saccule development|Clara cell differentiation|Type II pneumocyte differentiation|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|enzyme binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000021257,ANGEL1,angel homolog 1 (Drosophila),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0885,0,0,0,0.871,0,0,-1.2,1.7
ENSMUSG00000021423,LY86,lymphocyte antigen 86,extracellular region|,immune system process|inflammatory response|positive regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signaling pathway|innate immune response|,None,10,0.4,0.949,10,0,0,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000033059,PYGB,brain glycogen phosphorylase,cytoplasm|membrane|axon|,carbohydrate metabolic process|glycogen metabolic process|glycogen catabolic process|metabolic process|,"catalytic activity|phosphorylase activity|drug binding|glycogen phosphorylase activity|transferase activity|transferase activity, transferring glycosyl groups|pyridoxal phosphate binding|carbohydrate binding|protein homodimerization activity|",10,-0.3,1.1,10,0,0,0,0,0,0.871,0,0,-1.6,1.3
ENSMUSG00000010044,ZMYND10,"zinc finger, MYND domain containing 10",cytoplasm|cytoskeleton|centriolar satellite|,outer dynein arm assembly|inner dynein arm assembly|motile cilium assembly|,molecular_function|metal ion binding|,10,0.2,0.855,10,0,0,0,0,0,0.871,0,0,-1.2,1.7
ENSMUSG00000028497,PTPLAD2,protein tyrosine phosphatase-like A domain containing 2,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|biological_process|,molecular_function|lyase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000020167,TCF3,transcription factor 3,nuclear nucleosome|nuclear chromatin|nucleus|nucleus|transcription factor complex|transcription factor complex|transcription factor complex|cytoplasm|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|natural killer cell differentiation|B cell lineage commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|nervous system development|positive regulation of gene expression|positive regulation of gene expression|lymphocyte differentiation|cell differentiation|positive regulation of B cell proliferation|response to lipopolysaccharide|T cell differentiation in thymus|immunoglobulin V(D)J recombination|immunoglobulin V(D)J recombination|response to drug|histone H3 acetylation|histone H4 acetylation|positive regulation of neuron differentiation|positive regulation of cell cycle|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell development|Peyer's patch development|protein stabilization|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of G1/S transition of mitotic cell cycle|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|transcription factor binding|transcription factor binding|PDZ domain binding|mitogen-activated protein kinase kinase kinase binding|protein homodimerization activity|protein homodimerization activity|bHLH transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|repressing transcription factor binding|vitamin D response element binding|E-box binding|E-box binding|E-box binding|E-box binding|,10,0.5,0.0523,10,0,0,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000035033,TBR1,T-box brain gene 1,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|axon guidance|specification of organ identity|regulation of gene expression|regulation of neuron projection development|commitment of neuronal cell to specific neuron type in forebrain|neuron differentiation|hindbrain development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000026637,TRAF5,TNF receptor-associated factor 5,cytoplasm|centrosome|cytosol|cytoplasmic side of plasma membrane|CD40 receptor complex|,apoptotic process|signal transduction|positive regulation of cell proliferation|protein ubiquitination|regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|,ubiquitin-protein transferase activity|signal transducer activity|protein binding|zinc ion binding|ubiquitin protein ligase binding|thioesterase binding|metal ion binding|,10,0.3,0.738,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000032966,FKBP1A,FK506 binding protein 1a,intracellular|cell|cytoplasm|cytosol|membrane|membrane|Z disc|extracellular matrix|sarcoplasmic reticulum membrane|intracellular membrane-bounded organelle|axon terminus|extracellular vesicular exosome|,protein peptidyl-prolyl isomerization|protein peptidyl-prolyl isomerization|negative regulation of protein phosphorylation|heart morphogenesis|protein folding|muscle contraction|SMAD protein complex assembly|cytokine-mediated signaling pathway|response to caffeine|positive regulation of protein ubiquitination|positive regulation of protein binding|negative regulation of protein phosphatase type 2B activity|regulation of protein localization|regulation of activin receptor signaling pathway|T cell proliferation|positive regulation of I-kappaB kinase/NF-kappaB signaling|extracellular fibril organization|regulation of immune response|release of sequestered calcium ion into cytosol|release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion into cytosol|ventricular cardiac muscle tissue morphogenesis|regulation of ryanodine-sensitive calcium-release channel activity|regulation of ryanodine-sensitive calcium-release channel activity|heart trabecula formation|chaperone-mediated protein folding|regulation of amyloid precursor protein catabolic process|amyloid fibril formation|,peptidyl-prolyl cis-trans isomerase activity|peptidyl-prolyl cis-trans isomerase activity|signal transducer activity|transforming growth factor beta receptor binding|protein binding|FK506 binding|FK506 binding|FK506 binding|drug binding|isomerase activity|calcium channel inhibitor activity|enzyme binding|Hsp70 protein binding|type I transforming growth factor beta receptor binding|protein homodimerization activity|ion channel binding|SMAD binding|activin binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000035342,LZTS2,"leucine zipper, putative tumor suppressor 2",cytoplasm|cytoskeleton|microtubule|midbody|,kidney development|cell cycle|mitotic nuclear division|negative regulation of cell proliferation|positive regulation of cell death|Wnt signaling pathway|negative regulation of Wnt signaling pathway|cell division|renal system development|negative regulation of canonical Wnt signaling pathway|negative regulation of protein localization to nucleus|,None,10,0,0,10,-0.1,0.15,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000024190,DUSP1,dual specificity phosphatase 1,nucleus|cytoplasm|,endoderm formation|protein dephosphorylation|protein dephosphorylation|cell cycle|dephosphorylation|intracellular signal transduction|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of MAP kinase activity|negative regulation of ERK1 and ERK2 cascade|negative regulation of DNA biosynthetic process|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,10,0.4,0.212,10,0,0,0,0,0,0.871,0,0,-1,2
ENSMUSG00000030693,KLK10,kallikrein related-peptidase 10,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000050424,PNMA5,paraneoplastic antigen family 5,cellular_component|,biological_process|,molecular_function|,10,-0.5,0.602,9,0.1,0.183,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000044986,TST,"thiosulfate sulfurtransferase, mitochondrial",extracellular space|mitochondrion|mitochondrion|mitochondrial inner membrane|extracellular vesicular exosome|,epithelial cell differentiation|rRNA import into mitochondrion|rRNA transport|,RNA binding|thiosulfate sulfurtransferase activity|5S rRNA binding|transferase activity|,10,0,0,10,0.1,0.198,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000041132,N4BP2L1,NEDD4 binding protein 2-like 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000025246,TBL1X,transducin (beta)-like 1 X-linked,histone deacetylase complex|nucleus|transcription factor complex|spindle microtubule|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|proteolysis|sensory perception of sound|proteasome-mediated ubiquitin-dependent protein catabolic process|response to estrogen|fat cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|response to steroid hormone|canonical Wnt signaling pathway|",DNA binding|chromatin binding|transcription corepressor activity|transcription corepressor activity|protein binding|beta-catenin binding|protein C-terminus binding|transcription factor binding|protein domain specific binding|histone binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000053644,ALDH7A1,"aldehyde dehydrogenase family 7, member A1",nucleus|cytoplasm|mitochondrion|mitochondrion|extracellular vesicular exosome|,metabolic process|oxidation-reduction process|,"aldehyde dehydrogenase (NAD) activity|L-aminoadipate-semialdehyde dehydrogenase activity|betaine-aldehyde dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|",10,0.5,0.358,10,0.2,0.0782,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000014226,CACYBP,calcyclin binding protein,nucleus|nuclear envelope lumen|cytoplasm|cytoplasm|beta-catenin destruction complex|neuron projection|cell body|extracellular vesicular exosome|,positive regulation of DNA replication|cardiac muscle cell differentiation|response to growth hormone|negative regulation of cell death|,protein binding|protein homodimerization activity|,10,0.1,0.128,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000017386,TRAF4,TNF receptor associated factor 4,nucleus|cytoplasm|cytoskeleton|plasma membrane|tight junction|membrane|cell junction|,apoptotic process|signal transduction|activation of NF-kappaB-inducing kinase activity|multicellular organismal development|respiratory gaseous exchange|protein ubiquitination|respiratory tube development|regulation of apoptotic process|positive regulation of protein kinase activity|positive regulation of JNK cascade|positive regulation of protein homodimerization activity|,ubiquitin-protein transferase activity|tumor necrosis factor receptor binding|zinc ion binding|protein kinase binding|ubiquitin protein ligase binding|thioesterase binding|metal ion binding|WW domain binding|,10,0.3,0.824,10,0,0,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000018765,FXR2,"fragile X mental retardation, autosomal homolog 2",cytoplasm|membrane|extracellular vesicular exosome|,None,RNA binding|protein binding|identical protein binding|poly(A) RNA binding|,10,0,0,10,0.3,0.772,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000024962,VEGFB,vascular endothelial growth factor B,extracellular region|extracellular space|intracellular|membrane|,angiogenesis|positive regulation of endothelial cell proliferation|protein O-linked glycosylation|multicellular organismal development|heart development|negative regulation of gene expression|cell differentiation|positive regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of vascular wound healing|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|induction of positive chemotaxis|positive regulation of cell division|positive regulation of protein kinase B signaling|cardiac muscle contraction|positive regulation of mast cell chemotaxis|coronary vasculature development|positive regulation of ERK1 and ERK2 cascade|,growth factor activity|heparin binding|chemoattractant activity|protein homodimerization activity|vascular endothelial growth factor receptor 1 binding|protein heterodimerization activity|,10,0,0,10,-0.1,0.0636,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000024096,RALBP1,ralA binding protein 1,intracellular|membrane|neuron projection|,ATP catabolic process|transport|endocytosis|mitotic spindle organization|signal transduction|small GTPase mediated signal transduction|positive regulation of Rac GTPase activity|positive regulation of Rac GTPase activity|regulation of GTPase activity|positive regulation of Cdc42 GTPase activity|positive regulation of Cdc42 GTPase activity|negative regulation of smooth muscle cell proliferation|,"GTPase activator activity|GTPase activator activity|protein binding|ATPase activity|Ral GTPase binding|Ral GTPase binding|Rac GTPase activator activity|Rac GTPase activator activity|ATPase activity, coupled to movement of substances|Rac GTPase binding|",10,-0.1,0.0145,10,0.1,0.292,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000041429,NTHL1,nth (endonuclease III)-like 1 (E.coli),nucleus|nucleus|mitochondrion|,"DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|DNA repair|base-excision repair|base-excision repair, AP site formation|nucleotide-excision repair, DNA incision, 5'-to lesion|nucleotide-excision repair, DNA incision, 5'-to lesion|cellular response to DNA damage stimulus|metabolic process|","purine-specific mismatch base pair DNA N-glycosylase activity|DNA binding|double-stranded DNA binding|catalytic activity|DNA-(apurinic or apyrimidinic site) lyase activity|DNA-(apurinic or apyrimidinic site) lyase activity|nuclease activity|endonuclease activity|uracil DNA N-glycosylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|lyase activity|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA N-glycosylase activity|DNA-3-methylbase glycosylase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0,0,10,0.4,0.36,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000021379,ID4,inhibitor of DNA binding 4,nucleus|cytoplasm|,"G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|neuroblast proliferation|brain development|cell proliferation|positive regulation of cell proliferation|hippocampus development|cerebral cortex neuron differentiation|central nervous system myelination|cellular protein localization|fat cell differentiation|negative regulation of fat cell differentiation|negative regulation of neuron differentiation|positive regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of astrocyte differentiation|negative regulation of oligodendrocyte differentiation|",RNA polymerase II transcription factor binding|protein binding|protein dimerization activity|,10,0,0,10,0.1,0.127,0,0,0,0.871,0,0,-1.1,1.9
ENSMUSG00000030111,A2M,alpha-2-macroglobulin,extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,"negative regulation of complement activation, lectin pathway|female pregnancy|negative regulation of peptidase activity|negative regulation of endopeptidase activity|stem cell differentiation|",protease binding|endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|receptor binding|protein binding|growth factor binding|enzyme binding|interleukin-8 binding|interleukin-1 binding|peptidase inhibitor activity|tumor necrosis factor binding|calcium-dependent protein binding|,10,0.1,0.28,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000032508,MYD88,myeloid differentiation primary response gene 88,cytoplasm|cytosol|plasma membrane|postsynaptic density|protein complex|,response to molecule of fungal origin|immune system process|MyD88-dependent toll-like receptor signaling pathway|MyD88-dependent toll-like receptor signaling pathway|inflammatory response|immune response|signal transduction|cell surface receptor signaling pathway|transmembrane receptor protein serine/threonine kinase signaling pathway|JNK cascade|Toll signaling pathway|response to virus|immunoglobulin mediated immune response|cytokine-mediated signaling pathway|lipopolysaccharide-mediated signaling pathway|response to peptidoglycan|response to lipopolysaccharide|response to lipopolysaccharide|positive regulation of interleukin-17 production|positive regulation of interleukin-23 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|regulation of cell proliferation|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of growth of symbiont in host|positive regulation of chemokine biosynthetic process|innate immune response|type I interferon biosynthetic process|positive regulation of JNK cascade|positive regulation of smooth muscle cell proliferation|positive regulation of lymphocyte proliferation|regulation of inflammatory response|defense response to Gram-positive bacterium|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|response to interleukin-1|3'-UTR-mediated mRNA stabilization|establishment of endothelial intestinal barrier|,receptor binding|Toll binding|interleukin-1 receptor binding|protein binding|identical protein binding|TIR domain binding|,10,0,0,10,0.4,1.25,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000057163,PRSS2,"protease, serine 2",extracellular region|extracellular space|,proteolysis|digestion|collagen catabolic process|response to caffeine|response to nicotine|,catalytic activity|serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|metal ion binding|,10,-0.1,0.0339,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000030254,RAD18,RAD18 homolog (S. cerevisiae),chromatin|XY body|nucleus|replication fork|,DNA repair|cellular response to DNA damage stimulus|spermatogenesis|response to UV|negative regulation of DNA recombination|,"Y-form DNA binding|nucleic acid binding|DNA binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|polyubiquitin binding|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000018983,E2F2,E2F transcription factor 2,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|regulation of cell cycle|intrinsic apoptotic signaling pathway by p53 class mediator|lens fiber cell apoptotic process|",core promoter binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000021690,JMY,junction-mediating and regulatory protein,nucleus|nucleus|cytoplasm|cytoskeleton|cell leading edge|,DNA repair|regulation of transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|cell cycle arrest|Arp2/3 complex-mediated actin nucleation|positive regulation of apoptotic process|regulation of DNA-templated transcription in response to stress|positive regulation of sequence-specific DNA binding transcription factor activity|'de novo' actin filament nucleation|actin polymerization-dependent cell motility|intrinsic apoptotic signaling pathway by p53 class mediator|,transcription coactivator activity|actin binding|protein binding|,10,0,0,10,0.3,0.813,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000019302,ATP6V0A1,"ATPase, H+ transporting, lysosomal V0 subunit A1","vacuolar proton-transporting V-type ATPase, V0 domain|nucleus|cytoplasm|cytoplasm|Golgi apparatus|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|proton-transporting V-type ATPase, V0 domain|intracellular membrane-bounded organelle|extracellular vesicular exosome|",transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|,protein binding|hydrogen ion transmembrane transporter activity|ATPase binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000022840,ADCY5,adenylate cyclase 5,endosome|plasma membrane|plasma membrane|plasma membrane|cilium|membrane|integral component of membrane|sarcolemma|cell projection|membrane raft|primary cilium|,adenosine receptor signaling pathway|cAMP biosynthetic process|cAMP biosynthetic process|cAMP biosynthetic process|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|adenylate cyclase-inhibiting dopamine receptor signaling pathway|locomotory behavior|cyclic nucleotide biosynthetic process|intracellular signal transduction|neuromuscular process controlling balance|,nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|adenylate cyclase activity|protein binding|ATP binding|adenylate cyclase binding|calcium- and calmodulin-responsive adenylate cyclase activity|lyase activity|phosphorus-oxygen lyase activity|metal ion binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000028364,TNC,tenascin C,extracellular region|proteinaceous extracellular matrix|basement membrane|interstitial matrix|extracellular space|membrane|extracellular matrix|,osteoblast differentiation|cell adhesion|negative regulation of cell adhesion|neuromuscular junction development|positive regulation of cell proliferation|positive regulation of gene expression|peripheral nervous system axon regeneration|neuron projection development|bud outgrowth involved in lung branching|mesenchymal-epithelial cell signaling involved in prostate gland development|prostate gland epithelium morphogenesis|,fibronectin binding|syndecan binding|,10,-0.1,0.117,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000052525,SPDYA,speedy homolog A (Xenopus laevis),nucleus|nucleus|,G1/S transition of mitotic cell cycle|cellular response to DNA damage stimulus|cell cycle|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cyclin-dependent protein serine/threonine kinase activity|,protein kinase binding|protein kinase binding|,10,0,0,10,-0.6,1.86,0,0,0,0.871,0,0,-2,0.6
ENSMUSG00000020431,ADCY1,adenylate cyclase 1,nucleus|plasma membrane|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cAMP biosynthetic process|cAMP biosynthetic process|cAMP biosynthetic process|activation of adenylate cyclase activity|axonogenesis|long-term memory|cyclic nucleotide biosynthetic process|intracellular signal transduction|regulation of circadian rhythm|rhythmic process|,nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|calmodulin binding|ATP binding|calcium- and calmodulin-responsive adenylate cyclase activity|lyase activity|phosphorus-oxygen lyase activity|metal ion binding|,10,-0.1,0.0134,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000033857,ENGASE,endo-beta-N-acetylglucosaminidase,cellular_component|cytoplasm|,biological_process|metabolic process|,"molecular_function|hydrolase activity|hydrolase activity, acting on glycosyl bonds|mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity|",10,0.7,0.73,10,0,0,0,0,0,0.871,0,0,-0.7,2
ENSMUSG00000002228,PPM1J,protein phosphatase 1J,None,protein dephosphorylation|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein binding|hydrolase activity|,10,0,0,10,-0.2,0.352,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000021009,PTPN21,"protein tyrosine phosphatase, non-receptor type 21",cytoplasm|cytoskeleton|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,10,-0.5,0.353,10,0,0,0,0,0,0.871,0,0,-2,0.8
ENSMUSG00000030498,GAS2,growth arrest specific 2,cytoplasm|cytoskeleton|membrane|,apoptotic process|cell cycle|cell cycle arrest|regulation of cell shape|,None,10,0,0,10,0.1,0.363,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000041845,RHOD,"ras homolog gene family, member D",intracellular|endosome|plasma membrane|membrane|,small GTPase mediated signal transduction|,nucleotide binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000030483,CYP2B10,"cytochrome P450, family 2, subfamily b, polypeptide 10",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,xenobiotic metabolic process|steroid metabolic process|drug metabolic process|cellular ketone metabolic process|exogenous drug catabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|steroid hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|metal ion binding|aromatase activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000034926,DHCR24,24-dehydrocholesterol reductase,nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|cytosol|cytoskeleton|membrane|integral component of membrane|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|cholesterol biosynthetic process|Ras protein signal transduction|protein localization|steroid metabolic process|cholesterol metabolic process|negative regulation of cell proliferation|tissue development|tissue development|sterol metabolic process|sterol biosynthetic process|male genitalia development|plasminogen activation|amyloid precursor protein catabolic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|skin development|oxidation-reduction process|membrane organization|,"catalytic activity|UDP-N-acetylmuramate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor|enzyme binding|peptide antigen binding|delta24-sterol reductase activity|flavin adenine dinucleotide binding|",10,0,0,10,0.1,0.106,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000031520,VEGFC,vascular endothelial growth factor C,extracellular region|extracellular space|membrane|,angiogenesis|positive regulation of cell-matrix adhesion|positive regulation of neuroblast proliferation|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|organ morphogenesis|morphogenesis of embryonic epithelium|cell differentiation|regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of protein autophosphorylation|positive regulation of blood vessel endothelial cell migration|positive regulation of angiogenesis|negative regulation of blood pressure|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|positive regulation of epithelial cell proliferation|positive regulation of protein secretion|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|induction of positive chemotaxis|positive regulation of cell division|positive regulation of mast cell chemotaxis|positive regulation of lymphangiogenesis|,protein binding|growth factor activity|chemoattractant activity|vascular endothelial growth factor receptor 3 binding|vascular endothelial growth factor receptor 3 binding|,10,0,0,10,0.1,0.15,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000027221,CHST1,carbohydrate (keratan sulfate Gal-6) sulfotransferase 1,Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|galactose metabolic process|sulfur compound metabolic process|inflammatory response|keratan sulfate metabolic process|,sulfotransferase activity|transferase activity|keratan sulfotransferase activity|,10,0,0,10,-0.1,0.214,0,0,0,0.871,0,0,-1.5,1.4
ENSMUSG00000050840,CDH20,cadherin 20,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|,calcium ion binding|metal ion binding|,10,0,0,10,-0.2,1,0,0,0,0.871,0,0,-1.6,1.3
ENSMUSG00000009356,LPO,lactoperoxidase,extracellular space|cytoplasm|basolateral plasma membrane|extracellular vesicular exosome|,detection of chemical stimulus involved in sensory perception of bitter taste|thiocyanate metabolic process|defense response to bacterium|oxidation-reduction process|,peroxidase activity|oxidoreductase activity|thiocyanate peroxidase activity|,10,0,0,10,0.1,0.15,0,0,0,0.871,0,0,-1.3,1.8
ENSMUSG00000022935,GRIK1,"glutamate receptor, ionotropic, kainate 1",plasma membrane|ionotropic glutamate receptor complex|ionotropic glutamate receptor complex|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|dendrite|kainate selective glutamate receptor complex|presynaptic membrane|neuronal cell body|terminal bouton|receptor complex|synapse|postsynaptic membrane|neuronal postsynaptic density|,"transport|ion transport|cation transport|nervous system development|positive regulation of gamma-aminobutyric acid secretion|adult behavior|negative regulation of synaptic transmission, GABAergic|positive regulation of synaptic transmission, GABAergic|positive regulation of synaptic transmission, GABAergic|ion transmembrane transport|ion transmembrane transport|regulation of ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|synaptic transmission, glutamatergic|regulation of membrane potential|regulation of membrane potential|regulation of long-term neuronal synaptic plasticity|regulation of short-term neuronal synaptic plasticity|regulation of short-term neuronal synaptic plasticity|behavioral response to pain|membrane depolarization|negative regulation of synaptic transmission, glutamatergic|negative regulation of synaptic transmission, glutamatergic|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|regulation of inhibitory postsynaptic membrane potential|regulation of inhibitory postsynaptic membrane potential|",receptor activity|ionotropic glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|drug binding|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|glutamate binding|voltage-gated cation channel activity|protein homodimerization activity|,10,0,0,10,0.9,0.306,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000055197,FEV,FEV (ETS oncogene family),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|positive regulation of gene expression|cell differentiation|neuron maturation|positive regulation of transcription, DNA-templated|neuron fate specification|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.2,0.337,10,-0.3,0.169,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000024563,SMAD2,SMAD family member 2,nuclear chromatin|intracellular|cell|nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|cytoplasm|activin responsive factor complex|protein complex|SMAD protein complex|SMAD2-SMAD3 protein complex|,"in utero embryonic development|in utero embryonic development|endoderm formation|mesoderm formation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|common-partner SMAD protein phosphorylation|SMAD protein complex assembly|zygotic specification of dorsal/ventral axis|gastrulation|pattern specification process|endoderm development|heart development|negative regulation of cell proliferation|response to glucose|post-embryonic development|embryonic pattern specification|anterior/posterior pattern specification|positive regulation of epithelial to mesenchymal transition|regulation of transforming growth factor beta receptor signaling pathway|signal transduction involved in regulation of gene expression|insulin secretion|lung development|positive regulation of BMP signaling pathway|pancreas development|activin receptor signaling pathway|organ growth|intracellular signal transduction|intracellular signal transduction|nodal signaling pathway|cell fate commitment|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|paraxial mesoderm morphogenesis|developmental growth|embryonic foregut morphogenesis|embryonic cranial skeleton morphogenesis|regulation of binding|palate development|pericardium development|SMAD protein signal transduction|response to cholesterol|positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|","DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transforming growth factor beta receptor binding|protein binding|transcription factor binding|transcription factor binding|phosphatase binding|transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity|ubiquitin protein ligase binding|activating transcription factor binding|type I transforming growth factor beta receptor binding|SMAD binding|SMAD binding|metal ion binding|co-SMAD binding|I-SMAD binding|R-SMAD binding|",10,0.3,0.661,10,-1,1.82,0,0,0,0.871,0,0,-2,1
ENSMUSG00000030465,PSD3,pleckstrin and Sec7 domain containing 3,intracellular|plasma membrane|membrane|cell junction|synapse|postsynaptic membrane|,neuron differentiation|ARF protein signal transduction|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|,10,0.9,0.59,10,0,0,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000041559,FMOD,fibromodulin,extracellular region|proteinaceous extracellular matrix|extracellular space|intracellular|extracellular matrix|extracellular matrix|,None,None,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000038569,RAD9B,RAD9 homolog B,checkpoint clamp complex|,cell cycle checkpoint|DNA damage checkpoint|DNA repair|,None,10,1,2.99,10,-0.1,0.0492,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000053226,DAND5,"DAN domain family, member 5",extracellular region|extracellular region|,determination of left/right asymmetry in lateral mesoderm|ventricular septum development|atrial septum development|determination of left/right symmetry|determination of left/right symmetry|regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|sequestering of nodal from receptor via nodal binding|determination of heart left/right asymmetry|negative regulation of nodal signaling pathway|nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|,protein binding|morphogen activity|,10,0,0,10,0.1,0.174,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000038393,TXNIP,thioredoxin interacting protein,intracellular|cell|nucleus|cytoplasm|cytoplasm|mitochondrial intermembrane space|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|protein import into nucleus|response to oxidative stress|cell cycle|keratinocyte differentiation|regulation of cell proliferation|positive regulation of apoptotic process|negative regulation of catalytic activity|platelet-derived growth factor receptor signaling pathway|negative regulation of cell division|cellular response to tumor cell|",enzyme inhibitor activity|protein binding|ubiquitin protein ligase binding|,10,0,0,10,0.3,0.8,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000063089,KLK1B8,kallikrein 1-related peptidase b8,nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.0679,10,0,0,0,0,0,0.871,0,0,-1.3,1.6
ENSMUSG00000019856,FAM184A,"family with sequence similarity 184, member A",extracellular space|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000038241,CEP250,centrosomal protein 250,cytoplasm|centrosome|centriole|centriole|centriole|cytoskeleton|cilium|spindle pole centrosome|cell projection|protein complex|extracellular vesicular exosome|,mitotic cell cycle|cell cycle|protein localization|centriole-centriole cohesion|regulation of centriole-centriole cohesion|protein localization to organelle|,protein C-terminus binding|protein kinase binding|protein domain specific binding|,10,0,0,10,0.1,0.488,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000054555,ADAM12,a disintegrin and metallopeptidase domain 12 (meltrin alpha),plasma membrane|membrane|integral component of membrane|,proteolysis|cell adhesion|,metalloendopeptidase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|SH3 domain binding|metal ion binding|,10,0,0,10,-0.1,0.549,0,0,0,0.871,0,0,-1.4,1.5
ENSMUSG00000027082,TFPI,tissue factor pathway inhibitor,extracellular region|extracellular space|,blood coagulation|hemostasis|negative regulation of peptidase activity|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.2,0.769,10,-0.2,1.18,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000029546,UNCX,UNC homeobox,nucleus|,"cartilage condensation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|nervous system development|regulation of gene expression|dorsal spinal cord development|olfactory bulb interneuron differentiation|cell differentiation|common myeloid progenitor cell proliferation|regulation of cell differentiation|",DNA binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.7
ENSMUSG00000022994,ADCY6,adenylate cyclase 6,endosome|plasma membrane|plasma membrane|plasma membrane|cilium|membrane|integral component of membrane|microvillus membrane|sarcolemma|cell projection|membrane raft|,cAMP biosynthetic process|cAMP biosynthetic process|cAMP biosynthetic process|activation of adenylate cyclase activity|dopamine receptor signaling pathway|cyclic nucleotide biosynthetic process|negative regulation of neuron projection development|intracellular signal transduction|cellular response to prostaglandin E stimulus|cellular response to catecholamine stimulus|maintenance of protein location in plasma membrane|,SNARE binding|nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|adenylate cyclase activity|receptor binding|ATP binding|calcium- and calmodulin-responsive adenylate cyclase activity|lyase activity|phosphorus-oxygen lyase activity|protein kinase binding|metal ion binding|,10,0.1,0.414,10,-0.1,0.366,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000001157,GMCL1,germ cell-less homolog 1 (Drosophila),nucleus|nuclear envelope|nuclear matrix|,"regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|cell differentiation|",protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000027985,LEF1,lymphoid enhancer binding factor 1,nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|cytoplasm|protein-DNA complex|,"negative regulation of transcription from RNA polymerase II promoter|patterning of blood vessels|osteoblast differentiation|neural crest cell migration|somitogenesis|somitogenesis|epithelial to mesenchymal transition|vasculature development|sprouting angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of epithelial to mesenchymal transition|Wnt signaling pathway|Wnt signaling pathway|Wnt signaling pathway|Wnt signaling pathway|dentate gyrus development|hippocampus development|hypothalamus development|forebrain radial glial cell differentiation|forebrain neuroblast division|forebrain neuron differentiation|formation of radial glial scaffolds|regulation of cell-cell adhesion|negative regulation of cell-cell adhesion|positive regulation of cell-cell adhesion|regulation of Wnt signaling pathway|neutrophil differentiation|neutrophil differentiation|positive regulation of cell growth|embryonic limb morphogenesis|positive regulation of cell migration|BMP signaling pathway|positive regulation of granulocyte differentiation|mammary gland development|negative regulation of interleukin-13 production|negative regulation of interleukin-13 production|negative regulation of interleukin-4 production|negative regulation of interleukin-4 production|negative regulation of interleukin-5 production|negative regulation of interleukin-5 production|T cell receptor V(D)J recombination|B cell proliferation|odontogenesis of dentin-containing tooth|odontogenesis of dentin-containing tooth|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of DNA binding|steroid hormone mediated signaling pathway|tongue development|positive regulation by host of viral transcription|histone H3 acetylation|histone H4 acetylation|T-helper 1 cell differentiation|negative regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|alpha-beta T cell differentiation|eye pigmentation|paraxial mesoderm formation|cell development|muscle fiber development|sensory perception of taste|palate development|anatomical structure regression|canonical Wnt signaling pathway|canonical Wnt signaling pathway|face morphogenesis|cell chemotaxis|apoptotic process involved in morphogenesis|chorio-allantoic fusion|trachea gland development|cellular response to cytokine stimulus|cellular response to interleukin-4|positive regulation of cell proliferation in bone marrow|positive regulation of cell proliferation in bone marrow|negative regulation of apoptotic process in bone marrow|negative regulation of apoptotic process in bone marrow|odontoblast differentiation|odontoblast differentiation|negative regulation of estrogen receptor binding|positive regulation of cell cycle process|negative regulation of canonical Wnt signaling pathway|apoptotic process involved in patterning of blood vessels|","RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|beta-catenin binding|beta-catenin binding|transcription factor binding|DNA binding, bending|estrogen receptor activity|estrogen receptor binding|estrogen receptor binding|enhancer binding|enhancer binding|histone binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|sequence-specific DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|gamma-catenin binding|gamma-catenin binding|armadillo repeat domain binding|armadillo repeat domain binding|C2H2 zinc finger domain binding|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000021536,ADCY2,adenylate cyclase 2,intracellular|cytoplasm|plasma membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|dendrite|protein complex|membrane raft|,cAMP biosynthetic process|cAMP biosynthetic process|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|cyclic nucleotide biosynthetic process|intracellular signal transduction|,nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|ATP binding|adenylate cyclase binding|adenylate cyclase binding|calcium- and calmodulin-responsive adenylate cyclase activity|lyase activity|phosphorus-oxygen lyase activity|G-protein beta/gamma-subunit complex binding|metal ion binding|protein heterodimerization activity|protein heterodimerization activity|,9,0,0,9,-0.1,0.0762,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000078945,NAIP2,"NLR family, apoptosis inhibitory protein 2",extracellular vesicular exosome|IPAF inflammasome complex|,immune system process|apoptotic process|inflammatory response|detection of bacterium|defense response to bacterium|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|innate immune response|pyroptosis|cellular response to estrogen stimulus|,nucleotide binding|ATP binding|metal ion binding|,9,0,0,9,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000027242,WDR76,WD repeat domain 76,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.558,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000022577,LY6H,"lymphocyte antigen 6 complex, locus H",plasma membrane|membrane|anchored component of membrane|,None,None,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000079243,XIRP1,xin actin-binding repeat containing 1,cell-cell adherens junction|fascia adherens|intercalated disc|cell junction|,heart morphogenesis|negative regulation of cell proliferation|actin cytoskeleton organization|regulation of membrane potential|sarcomere organization|cardiac muscle cell development|,actin binding|filamin binding|poly(A) RNA binding|,10,0,0,10,0.1,0.00863,0,0,0,0.871,0,0,-1.2,1.8
ENSMUSG00000097328,TNFSF12,"tumor necrosis factor (ligand) superfamily, member 12",extracellular region|perinuclear region of cytoplasm|,extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|,None,10,0,0,10,0.1,0.214,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000030559,RAB38,"RAB38, member RAS oncogene family",cytoplasm|early endosome|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|membrane|cytoplasmic vesicle|vesicle|melanosome|phagocytic vesicle|,transport|organelle organization|small GTPase mediated signal transduction|protein transport|melanosome organization|endosome to melanosome transport|platelet dense granule organization|protein localization to membrane|phagosome acidification|,nucleotide binding|protein binding|GTP binding|GTP-dependent protein binding|protein complex binding|AP-1 adaptor complex binding|AP-3 adaptor complex binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.9,1.1
ENSMUSG00000028124,GCLM,"glutamate-cysteine ligase, modifier subunit",glutamate-cysteine ligase complex|glutamate-cysteine ligase complex|,cysteine metabolic process|glutamate metabolic process|glutathione metabolic process|glutathione biosynthetic process|glutathione biosynthetic process|response to oxidative stress|response to oxidative stress|apoptotic mitochondrial changes|positive regulation of glutamate-cysteine ligase activity|positive regulation of glutamate-cysteine ligase activity|response to drug|negative regulation of neuron apoptotic process|regulation of blood vessel size|response to nitrosative stress|regulation of mitochondrial depolarization|negative regulation of extrinsic apoptotic signaling pathway|,glutamate-cysteine ligase activity|glutamate-cysteine ligase activity|glutamate-cysteine ligase catalytic subunit binding|glutamate-cysteine ligase catalytic subunit binding|protein heterodimerization activity|protein heterodimerization activity|,10,0,0,10,0.9,0.389,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000022883,ROBO1,roundabout homolog 1 (Drosophila),cytoplasm|cell surface|membrane|integral component of membrane|axon|axolemma|neuronal cell body|,cell migration involved in sprouting angiogenesis|activation of cysteine-type endopeptidase activity involved in apoptotic process|chemotaxis|homophilic cell adhesion|multicellular organismal development|nervous system development|axon guidance|axon guidance|axon guidance|negative regulation of cell proliferation|axon midline choice point recognition|chemorepulsion involved in postnatal olfactory bulb interneuron migration|olfactory bulb interneuron development|cell differentiation|negative regulation of mammary gland epithelial cell proliferation|Roundabout signaling pathway|regulation of dendrite morphogenesis|positive regulation of axonogenesis|negative regulation of negative chemotaxis|mammary duct terminal end bud growth|negative regulation of chemokine-mediated signaling pathway|,protein binding|axon guidance receptor activity|LRR domain binding|identical protein binding|protein heterodimerization activity|,10,-0.2,0.476,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000038530,RGS4,regulator of G-protein signaling 4,cytoplasm|cytoplasm|cytoplasm|cytosol|plasma membrane|plasma membrane|membrane|protein complex|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|positive regulation of GTPase activity|negative regulation of G-protein coupled receptor protein signaling pathway|,G-protein alpha-subunit binding|GTPase activator activity|GTPase activator activity|GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.9
ENSMUSG00000022306,ZFPM2,"zinc finger protein, multitype 2",nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|vasculogenesis|vasculogenesis|in utero embryonic development|outflow tract septum morphogenesis|outflow tract morphogenesis|atrioventricular valve morphogenesis|mitral valve formation|tricuspid valve formation|right ventricular cardiac muscle tissue morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|heart development|lung development|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic organ development|embryonic organ development|cardiac muscle tissue development|cardiac muscle tissue morphogenesis|ventricular septum morphogenesis|negative regulation of cell death|vasculogenesis involved in coronary vascular morphogenesis|positive regulation of male gonad development|negative regulation of female gonad development|",nucleic acid binding transcription factor activity|nucleic acid binding|DNA binding|transcription corepressor activity|protein binding|transcription factor binding|transcription factor binding|metal ion binding|,10,0,0,10,-0.1,0.0935,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000018169,MFNG,MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,multicellular organismal development|pattern specification process|positive regulation of protein binding|positive regulation of Notch signaling pathway|,"protein binding|transferase activity|transferase activity, transferring glycosyl groups|O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity|metal ion binding|",10,0.1,0.00615,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000035273,HPSE,heparanase,extracellular region|proteinaceous extracellular matrix|nucleus|nucleus|lysosome|membrane|intracellular membrane-bounded organelle|membrane raft|,carbohydrate metabolic process|cell adhesion|cell-matrix adhesion|positive regulation vascular endothelial growth factor production|positive regulation of blood coagulation|heparan sulfate proteoglycan catabolic process|positive regulation of osteoblast proliferation|positive regulation of osteoblast proliferation|wound healing|regulation of hair follicle development|positive regulation of hair follicle development|positive regulation of protein kinase B signaling|positive regulation of protein kinase B signaling|angiogenesis involved in wound healing|vascular wound healing|,"hydrolase activity|hydrolase activity, acting on glycosyl bonds|heparanase activity|syndecan binding|protein dimerization activity|",10,0,0,10,0.1,0.258,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000020407,UPP1,uridine phosphorylase 1,cytoplasm|,pyrimidine nucleotide metabolic process|nucleoside metabolic process|nucleotide catabolic process|uridine metabolic process|,"catalytic activity|uridine phosphorylase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring pentosyl groups|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000026825,DNM1,dynamin 1,cytoplasm|cytoskeleton|microtubule|membrane coat|protein complex|,endocytosis|receptor-mediated endocytosis|endosome organization|receptor internalization|,nucleotide binding|GTPase activity|protein binding|GTP binding|protein C-terminus binding|hydrolase activity|protein complex binding|identical protein binding|poly(A) RNA binding|nitric-oxide synthase binding|,10,0.1,0.151,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000020085,AIFM2,"apoptosis-inducing factor, mitochondrion-associated 2",extracellular space|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|lipid particle|cytosol|membrane|integral component of membrane|,apoptotic mitochondrial changes|positive regulation of apoptotic process|positive regulation of apoptotic process|oxidation-reduction process|,DNA binding|electron-transferring-flavoprotein dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|flavin adenine dinucleotide binding|flavin adenine dinucleotide binding|epoxyqueuosine reductase activity|,10,0,0,10,-0.1,0.179,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000015829,TNR,tenascin R,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|nucleus|cytoplasm|cell surface|membrane raft|perineuronal net|,"cell adhesion|neuron cell-cell adhesion|negative regulation of cell adhesion|associative learning|negative regulation of neuron projection development|telencephalon cell migration|negative regulation of cell-cell adhesion|negative regulation of cell-cell adhesion|extracellular matrix organization|negative regulation of axon extension|locomotory exploration behavior|negative regulation of axon extension involved in regeneration|regulation of synaptic transmission|negative regulation of synaptic transmission|synapse organization|neuromuscular process controlling balance|positive regulation of synaptic transmission, glutamatergic|positive regulation of transmission of nerve impulse|long-term synaptic potentiation|",integrin binding|sphingolipid binding|,10,1.5,1.16,10,-0.1,0.221,0,0,0,0.871,0,0,-0.9,3
ENSMUSG00000041476,SMPX,"small muscle protein, X-linked",nucleus|cytoplasm|muscle tendon junction|M band|costamere|contractile fiber|,None,None,10,-0.1,0.0181,9,0,0,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000033016,NFATC1,"nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1",nuclear chromatin|nucleus|transcription factor complex|cytoplasm|,"G1/S transition of mitotic cell cycle|epithelial to mesenchymal transition|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|calcium ion transport|heart development|positive regulation of gene expression|osteoclast differentiation|intracellular signal transduction|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription coactivator binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|mitogen-activated protein kinase p38 binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000052387,TRPM3,"transient receptor potential cation channel, subfamily M, member 3",membrane|integral component of membrane|,transport|ion transport|cation transport|ion transmembrane transport|,cation channel activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000045636,MTUS1,mitochondrial tumor suppressor 1,extracellular space|nucleus|mitochondrion|Golgi apparatus|plasma membrane|membrane|,cell cycle|regulation of macrophage chemotaxis|,molecular_function|,10,-1.1,0.611,10,-0.4,1.14,0,0,0,0.871,0,0,-2,0.8
ENSMUSG00000021189,ATXN3,ataxin 3,nucleus|nucleus|cytoplasm|mitochondrial matrix|cytosol|mitochondrial membrane|nuclear inclusion body|,"microtubule cytoskeleton organization|transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|ubiquitin-dependent protein catabolic process|misfolded or incompletely synthesized protein catabolic process|regulation of cell-substrate adhesion|regulation of cell-substrate adhesion|actin cytoskeleton organization|cellular response to heat|monoubiquitinated protein deubiquitination|exploration behavior|proteasome-mediated ubiquitin-dependent protein catabolic process|intermediate filament cytoskeleton organization|protein K63-linked deubiquitination|protein K48-linked deubiquitination|cellular response to misfolded protein|",RNA polymerase II regulatory region DNA binding|ubiquitin thiolesterase activity|histone deacetylase activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|omega peptidase activity|hydrolase activity|ubiquitin protein ligase binding|ubiquitin protein ligase binding|identical protein binding|ATPase binding|Lys63-specific deubiquitinase activity|Lys48-specific deubiquitinase activity|,10,0,0,10,-0.2,0.487,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000030166,RAD52,RAD52 homolog (S. cerevisiae),nucleus|,double-strand break repair via homologous recombination|DNA repair|DNA recombination|cellular response to DNA damage stimulus|,DNA binding|identical protein binding|,10,0,0,10,0.1,0.39,0,0,0,0.871,0,0,-1.1,1.8
ENSMUSG00000052560,CPNE8,copine VIII,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.6,0.23,10,-0.1,0.0435,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000033111,3830406C13RIK,RIKEN cDNA 3830406C13 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.125,0,0,0,0.871,0,0,-2,1
ENSMUSG00000029999,TGFA,transforming growth factor alpha,extracellular region|extracellular space|nucleus|plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|cytoplasmic vesicle|perinuclear region of cytoplasm|,MAPK cascade|activation of MAPK activity|angiogenesis|protein phosphorylation|epidermal growth factor receptor signaling pathway|positive regulation of cell proliferation|negative regulation of apoptotic process|positive regulation of epidermal growth factor-activated receptor activity|positive regulation of mitosis|negative regulation of cellular process|positive regulation of epithelial cell proliferation|positive regulation of cell division|mammary gland alveolus development|,glycoprotein binding|MAP kinase kinase activity|epidermal growth factor receptor binding|growth factor activity|,10,0.3,0.351,10,0,0,0,0,0,0.871,0,0,-1.1,1.9
ENSMUSG00000018012,RAC3,RAS-related C3 botulinum substrate 3,intracellular|cytoplasm|cytoskeleton|plasma membrane|endomembrane system|membrane|growth cone|filamentous actin|cell projection|neuron projection|neuronal cell body|perinuclear region of cytoplasm|cell periphery|,GTP catabolic process|small GTPase mediated signal transduction|cell projection assembly|actin cytoskeleton organization|neuron projection development|positive regulation of cell adhesion mediated by integrin|neuromuscular process controlling balance|neuromuscular process|positive regulation of substrate adhesion-dependent cell spreading|,nucleotide binding|GTPase activity|protein binding|GTP binding|calcium-dependent protein binding|,10,0,0,10,-0.2,0.736,0,0,0,0.871,0,0,-1.7,1.2
ENSMUSG00000041607,MBP,myelin basic protein,nucleus|cytoplasm|plasma membrane|membrane|internode region of axon|cell projection|neuronal cell body|myelin sheath|cell periphery|,response to toxic substance|myelination|membrane organization|,protease binding|structural constituent of myelin sheath|,10,0.1,0.106,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000021613,HAPLN1,hyaluronan and proteoglycan link protein 1,extracellular region|proteinaceous extracellular matrix|extracellular matrix|,cell adhesion|,hyaluronic acid binding|,10,0.2,0.839,10,-0.8,0.0435,0,0,0,0.871,0,0,-2,1
ENSMUSG00000000385,TMPRSS2,"transmembrane protease, serine 2",extracellular region|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,proteolysis|proteolysis|protein autoprocessing|positive regulation of viral entry into host cell|,catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.2,0.538,0,0,0,0.871,0,0,-1.7,1.2
ENSMUSG00000055301,ADH7,"alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide",extracellular region|intracellular|cytoplasm|,retinoid metabolic process|ethanol metabolic process|ethanol catabolic process|ethanol oxidation|response to bacterium|fatty acid omega-oxidation|retinol metabolic process|retinol metabolic process|retinoic acid metabolic process|response to ethanol|oxidation-reduction process|oxidation-reduction process|extracellular negative regulation of signal transduction|negative regulation of receptor activity|,"alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase activity, zinc-dependent|aldehyde oxidase activity|retinol dehydrogenase activity|retinol dehydrogenase activity|zinc ion binding|oxidoreductase activity|retinol binding|ethanol binding|protein homodimerization activity|metal ion binding|receptor antagonist activity|NAD binding|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000057021,VMN2R-PS159,"vomeronasal 2, receptor, pseudogene 159",None,None,None,10,0,0,10,0.3,0.596,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000004071,CDIP1,cell death inducing Trp53 target 1,nucleus|,apoptotic process|tumor necrosis factor-mediated signaling pathway|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|,None,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000022875,KNG1,kininogen 1,extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,inflammatory response|blood coagulation|hemostasis|negative regulation of peptidase activity|negative regulation of endopeptidase activity|vasodilation|regulation of blood vessel size|,cysteine-type endopeptidase inhibitor activity|receptor binding|peptidase inhibitor activity|,10,0,0,10,-0.1,0.165,0,0,0,0.871,0,0,-1.6,1.3
ENSMUSG00000048387,OSR1,odd-skipped related 1 (Drosophila),nucleus|,"negative regulation of transcription from RNA polymerase II promoter|urogenital system development|metanephros development|ureteric bud development|mesonephros development|chondrocyte differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|gonad development|positive regulation of gene expression|cell differentiation|positive regulation of bone mineralization|negative regulation of epithelial cell differentiation|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic skeletal limb joint morphogenesis|middle ear morphogenesis|odontogenesis|embryonic digit morphogenesis|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|intermediate mesoderm development|pronephros development|stem cell differentiation|positive regulation of epithelial cell proliferation|palate development|embryonic skeletal joint morphogenesis|metanephric mesenchyme development|cell proliferation involved in kidney development|metanephric mesenchyme morphogenesis|mesangial cell development|metanephric mesenchymal cell differentiation|posterior mesonephric tubule development|specification of anterior mesonephric tubule identity|specification of posterior mesonephric tubule identity|mesonephric duct morphogenesis|negative regulation of nephron tubule epithelial cell differentiation|renal vesicle progenitor cell differentiation|ureter urothelium development|metanephric epithelium development|metanephric smooth muscle tissue development|metanephric nephron tubule development|metanephric glomerulus vasculature development|metanephric interstitial cell development|pattern specification involved in metanephros development|embryonic skeletal joint development|metanephric cap mesenchymal cell proliferation involved in metanephros development|positive regulation of gastrulation|",nucleic acid binding|metal ion binding|,10,0,0,10,-0.3,0.566,0,0,0,0.871,0,0,-1.8,1.1
ENSMUSG00000040945,RCC2,regulator of chromosome condensation 2,"chromosome, centromeric region|nucleus|chromosome|cytoplasm|cytoskeleton|microtubule|midbody|chromosome, centromeric core region|mitotic spindle midzone|",mitotic cell cycle|endosome organization|cell cycle|mitotic nuclear division|integrin-mediated signaling pathway|positive regulation of G2/M transition of mitotic cell cycle|regulation of cell migration|negative regulation of GTPase activity|focal adhesion assembly|cell division|negative regulation of focal adhesion assembly|positive regulation of attachment of spindle microtubules to kinetochore|chromosome passenger complex localization to kinetochore|negative regulation of substrate adhesion-dependent cell spreading|,microtubule binding|poly(A) RNA binding|Rac GTPase binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000028417,TAL2,T cell acute lymphocytic leukemia 2,None,"transcription, DNA-templated|regulation of transcription, DNA-templated|post-embryonic development|thalamus development|midbrain development|multicellular organism growth|",DNA binding|protein dimerization activity|,10,0,0,10,0.1,0.0757,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000055694,GDF1,growth differentiation factor 1,None,in utero embryonic development|signal transduction|signal transduction|endoderm development|mesoderm development|,None,10,0.1,0.117,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000030513,PCSK6,proprotein convertase subtilisin/kexin type 6,extracellular space|extracellular space|Golgi apparatus|cell surface|extracellular matrix|,"proteolysis|zygotic determination of anterior/posterior axis, embryo|zygotic determination of anterior/posterior axis, embryo|determination of left/right symmetry|glycoprotein metabolic process|protein processing|protein processing|peptide hormone processing|nerve growth factor production|secretion by cell|",endopeptidase activity|serine-type endopeptidase activity|serine-type endopeptidase activity|heparin binding|peptidase activity|serine-type peptidase activity|hydrolase activity|nerve growth factor binding|,10,0,0,10,-0.1,0.278,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000022376,ADCY8,adenylate cyclase 8,intracellular|plasma membrane|membrane|integral component of membrane|,cAMP biosynthetic process|cAMP biosynthetic process|adenylate cyclase-activating G-protein coupled receptor signaling pathway|long-term memory|cyclic nucleotide biosynthetic process|cAMP-mediated signaling|intracellular signal transduction|,nucleotide binding|adenylate cyclase activity|calmodulin binding|ATP binding|protein C-terminus binding|calcium- and calmodulin-responsive adenylate cyclase activity|lyase activity|phosphorus-oxygen lyase activity|metal ion binding|protein N-terminus binding|,9,-0.2,0.513,9,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000021994,WNT5A,"wingless-type MMTV integration site family, member 5A",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|intracellular|cytoplasm|cell surface|extracellular matrix|,"activation of MAPK activity|ameboidal cell migration|establishment of planar polarity|somitogenesis|neural tube closure|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|heart looping|morphogenesis of an epithelium|positive regulation of mesenchymal cell proliferation|positive regulation of cytokine secretion involved in immune response|type B pancreatic cell development|pericardium morphogenesis|axis elongation|protein phosphorylation|signal transduction|Wnt signaling pathway, calcium modulating pathway|Wnt signaling pathway, calcium modulating pathway|Wnt signaling pathway, calcium modulating pathway|JNK cascade|activation of JUN kinase activity|cell-cell signaling|multicellular organismal development|determination of left/right symmetry|axon guidance|hindgut morphogenesis|midgut development|positive regulation of cell proliferation|positive regulation of cell proliferation|male gonad development|anterior/posterior axis specification, embryo|embryo development|organ morphogenesis|anterior/posterior pattern specification|positive regulation of endothelial cell migration|positive regulation of peptidyl-threonine phosphorylation|positive regulation of T cell chemotaxis|positive regulation of neuron projection development|Wnt signaling pathway|Wnt signaling pathway|cell migration|cell migration|olfactory bulb interneuron development|neural tube development|positive regulation of cell-cell adhesion|cell differentiation|lung development|embryonic limb morphogenesis|negative regulation of BMP signaling pathway|positive regulation of cGMP metabolic process|activation of protein kinase B activity|positive regulation of interferon-gamma production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of peptidyl-serine phosphorylation|cellular protein localization|cellular protein localization|limb morphogenesis|post-anal tail morphogenesis|post-anal tail morphogenesis|non-canonical Wnt signaling pathway via JNK cascade|negative regulation of fibroblast growth factor receptor signaling pathway|wound healing|inner ear morphogenesis|inner ear morphogenesis|embryonic digit morphogenesis|positive regulation of macrophage activation|negative regulation of apoptotic process|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|positive regulation of chemokine biosynthetic process|cell fate commitment|negative regulation of fat cell differentiation|positive regulation of protein catabolic process|positive regulation of angiogenesis|positive regulation of ossification|positive regulation of meiosis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|development of primary male sexual characteristics|positive regulation of fibroblast proliferation|digestive tract morphogenesis|embryonic skeletal system development|genitalia development|neuron projection morphogenesis|negative regulation of axon extension involved in axon guidance|hypophysis morphogenesis|positive regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|positive regulation of inflammatory response|negative chemotaxis|positive regulation of NF-kappaB transcription factor activity|cartilage development|negative regulation of synapse assembly|palate development|convergent extension|convergent extension involved in organogenesis|uterus development|cervix development|vagina development|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|urinary bladder development|face development|positive regulation of type I interferon-mediated signaling pathway|lateral sprouting involved in mammary gland duct morphogenesis|tube closure|mesenchymal-epithelial cell signaling|negative regulation of prostatic bud formation|mammary gland branching involved in thelarche|epithelial cell proliferation involved in mammary gland duct elongation|positive regulation of response to cytokine stimulus|regulation of branching involved in mammary gland duct morphogenesis|regulation of branching involved in mammary gland duct morphogenesis|positive regulation of macrophage cytokine production|positive regulation of cartilage development|positive regulation of cartilage development|planar cell polarity pathway involved in outflow tract morphogenesis|planar cell polarity pathway involved in ventricular septum morphogenesis|planar cell polarity pathway involved in cardiac right atrium morphogenesis|planar cell polarity pathway involved in cardiac muscle tissue morphogenesis|planar cell polarity pathway involved in pericardium morphogenesis|positive regulation of thymocyte apoptotic process|cellular response to molecule of bacterial origin|hematopoietic stem cell proliferation|hematopoietic stem cell proliferation|hematopoietic stem cell proliferation|dopaminergic neuron differentiation|dopaminergic neuron differentiation|negative regulation of mesenchymal cell proliferation|primitive streak formation|positive regulation of protein kinase C signaling|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|cochlea morphogenesis|cochlea morphogenesis|planar cell polarity pathway involved in neural tube closure|positive regulation of cell-cell adhesion mediated by cadherin|positive regulation of interleukin-8 secretion|",sequence-specific DNA binding transcription factor activity|receptor binding|receptor binding|frizzled binding|frizzled binding|frizzled-2 binding|receptor tyrosine kinase-like orphan receptor binding|cytokine activity|protein binding|protein domain specific binding|transcription regulatory region DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000036106,PRR5,proline rich 5 (renal),TORC2 complex|,positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|cell cycle|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of phosphatidylinositol 3-kinase signaling|actin cytoskeleton organization|positive regulation of cell migration|positive regulation of GTPase activity|,GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.1,2
ENSMUSG00000034957,CEBPA,"CCAAT/enhancer binding protein (C/EBP), alpha",nucleus|nucleus|transcription factor complex|transcription factor complex|nuclear matrix|Rb-E2F complex|protein complex|,"urea cycle|negative regulation of transcription from RNA polymerase II promoter|liver development|embryonic placenta development|transcription, DNA-templated|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|mitochondrion organization|cholesterol metabolic process|negative regulation of cell proliferation|cytokine-mediated signaling pathway|myeloid cell differentiation|macrophage differentiation|lung development|regulation of cell proliferation|fat cell differentiation|positive regulation of fat cell differentiation|positive regulation of fat cell differentiation|positive regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase III promoter|cell maturation|inner ear development|white fat cell differentiation|brown fat cell differentiation|cellular response to lithium ion|cellular response to organic cyclic compound|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein domain specific binding|protein complex binding|protein homodimerization activity|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|HMG box domain binding|,10,0,0,10,-0.2,0.76,0,0,0,0.871,0,0,-1.5,1.4
ENSMUSG00000026837,COL5A1,"collagen, type V, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen trimer|collagen type V trimer|basement membrane|extracellular matrix|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,"blood vessel development|heart morphogenesis|cell adhesion|cell migration|collagen fibril organization|collagen fibril organization|collagen fibril organization|collagen biosynthetic process|wound healing, spreading of epidermal cells|tendon development|tendon development|extracellular fibril organization|skin development|skin development|integrin biosynthetic process|eye morphogenesis|regulation of cellular component organization|",extracellular matrix structural constituent|protein binding|heparin binding|proteoglycan binding|platelet-derived growth factor binding|,10,0,0,10,-0.2,1.04,0,0,0,0.871,0,0,-1.1,1.7
ENSMUSG00000050069,GREM2,"gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)",extracellular region|extracellular space|,multicellular organismal development|embryonic body morphogenesis|cytokine-mediated signaling pathway|negative regulation of BMP signaling pathway|sequestering of BMP from receptor via BMP binding|determination of dorsal identity|regulation of cytokine activity|,cytokine activity|heparin binding|BMP binding|protein homodimerization activity|,10,0.3,0.745,10,0,0,0,0,0,0.871,0,0,-0.9,1.9
ENSMUSG00000048264,DIP2C,DIP2 disco-interacting protein 2 homolog C (Drosophila),cellular_component|,biological_process|,molecular_function|,10,0.1,0.139,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000028796,PHC2,polyhomeotic-like 2 (Drosophila),heterochromatin|nucleus|nucleus|PcG protein complex|PcG protein complex|PRC1 complex|,multicellular organismal development|spermatogenesis|,DNA binding|protein binding|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000075053,VDAC3-PS1,"voltage-dependent anion channel 3, pseudogene 1",None,None,None,9,0,0,9,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000079102,DAB2,"disabled 2, mitogen-responsive phosphoprotein",nucleus|nucleolus|cytoplasm|plasma membrane|plasma membrane|coated pit|membrane|apical plasma membrane|clathrin coat of coated pit|clathrin-coated vesicle membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|transforming growth factor beta receptor homodimeric complex|extracellular vesicular exosome|,"cell morphogenesis involved in differentiation|in utero embryonic development|positive regulation of receptor recycling|positive regulation of protein phosphorylation|transport|endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|pinocytosis|apoptotic process|activation of JUN kinase activity|multicellular organismal development|endoderm development|excretion|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of neuron projection development|protein transport|Wnt signaling pathway|cell differentiation|negative regulation of cell growth|positive regulation of cell migration|positive regulation of transforming growth factor beta receptor signaling pathway|negative regulation of protein binding|positive regulation of aldosterone biosynthetic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of transcription elongation from RNA polymerase II promoter|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of cell adhesion|positive regulation of cell adhesion|positive regulation of endocytosis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|clathrin coat assembly|clathrin coat assembly|response to steroid hormone|negative regulation of epithelial cell proliferation|positive regulation of SMAD protein import into nucleus|negative regulation of androgen receptor signaling pathway|negative regulation of ERK1 and ERK2 cascade|cellular response to epidermal growth factor stimulus|cellular response to transforming growth factor beta stimulus|negative regulation of canonical Wnt signaling pathway|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of Wnt signaling pathway, planar cell polarity pathway|regulation of Rho-dependent protein serine/threonine kinase activity|positive regulation of clathrin-mediated endocytosis|positive regulation of clathrin-mediated endocytosis|positive regulation of early endosome to late endosome transport|positive regulation of aldosterone secretion|positive regulation of integrin-mediated signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|","integrin binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|protein C-terminus binding|clathrin binding|phosphatidylinositol binding|AP-2 adaptor complex binding|clathrin adaptor activity|clathrin adaptor activity|cargo receptor activity|cargo receptor activity|SMAD binding|",10,-0.2,0.405,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000020263,APPL2,"adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2",nucleus|cytoplasm|endosome|endosome membrane|membrane|NuRD complex|extracellular vesicular exosome|,cell cycle|cell proliferation|,Rab GTPase binding|,10,0.5,0.0943,10,0,0,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000079492,GM11127,predicted gene 11127,None,None,None,10,0.1,0.702,10,0,0,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000041650,PCCA,"propionyl-Coenzyme A carboxylase, alpha polypeptide",mitochondrion|mitochondrion|,metabolic process|,nucleotide binding|catalytic activity|biotin carboxylase activity|propionyl-CoA carboxylase activity|ATP binding|ligase activity|enzyme binding|metal ion binding|,10,0,0,10,0.8,0.686,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000039323,IGFBP2,insulin-like growth factor binding protein 2,extracellular region|extracellular space|extracellular space|apical plasma membrane|cytoplasmic vesicle|extracellular vesicular exosome|,regulation of cell growth|regulation of growth|positive regulation of activated T cell proliferation|,insulin-like growth factor binding|growth factor binding|insulin-like growth factor I binding|insulin-like growth factor II binding|,10,-0.1,0.581,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000031616,EDNRA,endothelin receptor type A,plasma membrane|membrane|integral component of membrane|T-tubule|nuclear membrane|membrane raft|,patterning of blood vessels|response to hypoxia|in utero embryonic development|histamine secretion|positive regulation of protein phosphorylation|glomerular filtration|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|protein kinase C-activating G-protein coupled receptor signaling pathway|Rho protein signal transduction|heart development|respiratory gaseous exchange|positive regulation of cell proliferation|neural crest cell development|artery smooth muscle contraction|glucose transport|sensory perception of pain|negative regulation of cAMP biosynthetic process|response to lipopolysaccharide|vasoconstriction|vasoconstriction|positive regulation of odontogenesis|negative regulation of apoptotic process|penile erection|response to morphine|fibroblast proliferation|enteric nervous system development|smooth muscle cell proliferation|regulation of epithelial cell proliferation|positive regulation of inflammatory response|positive regulation of release of sequestered calcium ion into cytosol|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|positive regulation of calcium ion transport|head development|positive regulation of ERK1 and ERK2 cascade|cellular response to mechanical stimulus|endothelin receptor signaling pathway|positive regulation of neutrophil chemotaxis|positive regulation of kidney development|,signal transducer activity|G-protein coupled receptor activity|endothelin receptor activity|endothelin receptor activity|protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000032174,ICAM5,"intercellular adhesion molecule 5, telencephalin",plasma membrane|membrane|integral component of membrane|,phagocytosis|cell adhesion|single organismal cell-cell adhesion|,protein binding|,10,0.3,0.734,10,0,0,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000032908,SGPP2,sphingosine-1-phosphate phosphotase 2,endoplasmic reticulum|membrane|integral component of membrane|,sphingosine metabolic process|dephosphorylation|,"catalytic activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|sphingosine-1-phosphate phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0.3,0.364,10,-0.1,0.182,0,0,0,0.871,0,0,-1.3,1.6
ENSMUSG00000027011,UBE2E3,ubiquitin-conjugating enzyme E2E 3,nucleus|cytoplasm|,regulation of growth|protein K63-linked ubiquitination|protein K48-linked ubiquitination|protein K11-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|,10,-0.1,0.18,10,0,0,0,0,0,0.871,0,0,-1.8,1.1
ENSMUSG00000008461,FUT1,fucosyltransferase 1,None,fucosylation|,"galactoside 2-alpha-L-fucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,10,-0.1,0.039,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000021461,FANCC,"Fanconi anemia, complementation group C",chromatin|nucleus|cytoplasm|cytosol|Fanconi anaemia nuclear complex|,myeloid cell homeostasis|myeloid cell homeostasis|DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|gamete generation|germ cell development|removal of superoxide radicals|,None,10,-0.1,0.1,10,0,0,0,0,0,0.871,0,0,-2,1.1
ENSMUSG00000031273,COL4A6,"collagen, type IV, alpha 6",collagen trimer|collagen type IV trimer|basement membrane|,extracellular matrix organization|cellular response to amino acid stimulus|,structural molecule activity|,10,0.3,1.18,10,-0.9,2.82,0,0,0,0.871,0,0,-2,0.9
ENSMUSG00000067370,B3GALT4,"UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4",cellular_component|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|biological_process|,"molecular_function|galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|ganglioside galactosyltransferase activity|",10,0,0,10,-0.1,0.0636,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000024985,TCF7L2,"transcription factor 7 like 2, T cell specific, HMG box",nuclear chromatin|nucleus|nucleus|nucleoplasm|transcription factor complex|cytoplasm|cytosol|protein-DNA complex|beta-catenin-TCF7L2 complex|catenin-TCF7L2 complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|blood vessel development|glycogen metabolic process|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|cell cycle arrest|cell proliferation|cellular response to starvation|response to glucose|post-embryonic development|positive regulation of triglyceride biosynthetic process|positive regulation of heparan sulfate proteoglycan biosynthetic process|oligodendrocyte development|Wnt signaling pathway|Wnt signaling pathway|neural tube development|pituitary gland development|bone mineralization|negative regulation of BMP signaling pathway|embryonic genitalia morphogenesis|regulation of myelination|positive regulation of insulin secretion|positive regulation of insulin secretion|positive regulation of protein binding|secretory granule localization|regulation of hormone metabolic process|somatic stem cell maintenance|somatic stem cell maintenance|multicellular organism growth|catenin import into nucleus|negative regulation of fibroblast growth factor receptor signaling pathway|odontogenesis of dentin-containing tooth|glucose homeostasis|positive regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|maintenance of DNA repeat elements|skin development|canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition|fat cell differentiation|negative regulation of fat cell differentiation|positive regulation of gluconeogenesis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of organ growth|positive regulation of protein export from nucleus|positive regulation of lipid biosynthetic process|embryonic digestive tract morphogenesis|embryonic hindgut morphogenesis|myoblast fate commitment|myoblast fate commitment|regulation of skeletal muscle tissue development|regulation of smooth muscle cell proliferation|regulation of oligodendrocyte differentiation|positive regulation of epithelial cell proliferation|positive regulation of protein kinase B signaling|canonical Wnt signaling pathway|face morphogenesis|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of insulin secretion involved in cellular response to glucose stimulus|negative regulation of canonical Wnt signaling pathway|insulin metabolic process|negative regulation of type B pancreatic cell apoptotic process|negative regulation of extrinsic apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II repressing transcription factor binding|DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|beta-catenin binding|beta-catenin binding|beta-catenin binding|transcription factor binding|protein kinase binding|nuclear hormone receptor binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|gamma-catenin binding|armadillo repeat domain binding|,10,0,0,10,-0.1,0.0129,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000090084,SRPX,sushi-repeat-containing protein,autophagic vacuole|endoplasmic reticulum|,phagolysosome assembly|autophagy|response to endoplasmic reticulum stress|negative regulation of cell proliferation involved in contact inhibition|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,protein binding|,10,0.1,0.067,10,-0.1,0.342,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000024780,CDC37L1,cell division cycle 37-like 1,cytoplasm|,biological_process|,molecular_function|,9,0,0,10,0.1,0.156,0,0,0,0.871,0,0,-1.2,1.9
ENSMUSG00000082229,NAP1L2,nucleosome assembly protein 1-like 2,nucleus|,nucleosome assembly|positive regulation of histone acetylation|positive regulation of neuron differentiation|positive regulation of histone H3-K14 acetylation|regulation of stem cell division|positive regulation of histone H3-K9 acetylation|,chromatin binding|histone binding|,10,0.1,0.0679,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000035637,GRHPR,glyoxylate reductase/hydroxypyruvate reductase,cytoplasm|cytosol|extracellular vesicular exosome|,excretion|metabolic process|dicarboxylic acid metabolic process|protein oligomerization|oxidation-reduction process|,"glycerate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|hydroxypyruvate reductase activity|glyoxylate reductase (NADP) activity|carboxylic acid binding|protein homodimerization activity|NADP binding|NAD binding|NADPH binding|",10,0,0,10,0.1,0.00624,0,0,0,0.871,0,0,-1.1,1.9
ENSMUSG00000020325,FSTL3,follistatin-like 3,extracellular region|extracellular space|extracellular space|nucleus|Golgi apparatus|secretory granule|neuron projection terminus|,"ossification|hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|positive regulation of cell-cell adhesion|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of activin receptor signaling pathway|negative regulation of osteoclast differentiation|positive regulation of transcription from RNA polymerase II promoter|negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway|",fibronectin binding|activin binding|activin binding|,10,0.1,0.116,10,0,0,0,0,0,0.871,0,0,-1.1,1.9
ENSMUSG00000027490,E2F1,E2F transcription factor 1,nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|Rb-E2F complex|,"DNA damage checkpoint|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cell cycle|intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of gene expression|forebrain development|anoikis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fibroblast proliferation|mRNA stabilization|regulation of cell cycle|cellular response to growth factor stimulus|negative regulation of transcription involved in G1/S transition of mitotic cell cycle|intrinsic apoptotic signaling pathway by p53 class mediator|lens fiber cell apoptotic process|regulation of G1/S transition of mitotic cell cycle|",core promoter binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|transcription factor binding|sequence-specific DNA binding|,10,0,0,10,0.4,0.119,0,0,0,0.871,0,0,-1.3,1.6
ENSMUSG00000037373,CTBP1,C-terminal binding protein 1,nucleus|nucleus|transcription factor complex|cytoplasm|cytosol|transcriptional repressor complex|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|Golgi organization|metabolic process|cell differentiation|positive regulation of histone deacetylation|regulation of transcription by chromatin organization|negative regulation of histone acetylation|negative regulation of transcription, DNA-templated|white fat cell differentiation|regulation of cell cycle|oxidation-reduction process|negative regulation of histone H4 acetylation|","C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|RNA polymerase II transcription corepressor activity|sequence-specific DNA binding transcription factor activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|protein binding|transcription factor binding|transcription factor binding|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|protein domain specific binding|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|protein homodimerization activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|NAD binding|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|repressing transcription factor binding|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000019865,NMBR,neuromedin B receptor,cytoplasm|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|bombesin receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|bombesin receptor activity|neuropeptide receptor activity|,9,-0.5,0.17,9,0,0,0,0,0,0.871,0,0,-2,1
ENSMUSG00000059305,VPREB1,pre-B lymphocyte gene 1,plasma membrane|external side of plasma membrane|,cell morphogenesis|immunoglobulin production|immune response|regulation of cell size|regulation of cell size|hemopoiesis|B cell proliferation|B cell proliferation|homeostasis of number of cells|,receptor activity|protein binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.4,1.7
ENSMUSG00000054364,RHOB,"ras homolog gene family, member B",intracellular|nucleus|endosome|cytosol|plasma membrane|plasma membrane|endosome membrane|membrane|membrane|cleavage furrow|extracellular vesicular exosome|,cytokinesis|angiogenesis|transport|apoptotic process|transformed cell apoptotic process|cell adhesion|small GTPase mediated signal transduction|multicellular organismal development|endosome to lysosome transport|protein transport|cell differentiation|positive regulation of apoptotic process|positive regulation of angiogenesis|negative regulation of cell cycle|cellular response to hydrogen peroxide|cellular response to ionizing radiation|,nucleotide binding|protein binding|GTP binding|GDP binding|,10,0,0,10,0.1,0.279,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000037347,CHST7,carbohydrate (N-acetylglucosamino) sulfotransferase 7,Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|N-acetylglucosamine metabolic process|sulfur compound metabolic process|chondroitin sulfate biosynthetic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|chondroitin 6-sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0.4,0.549,10,0,0,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000063015,CCNI,cyclin I,None,regulation of protein kinase activity|regulation of cell cycle|,cyclin-dependent protein serine/threonine kinase regulator activity|,10,0,0,10,0.1,0.253,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000035686,THRSP,thyroid hormone responsive,nucleus|cytoplasm|cytosol|,"transcription, DNA-templated|regulation of transcription, DNA-templated|lipid metabolic process|regulation of triglyceride biosynthetic process|regulation of lipid biosynthetic process|regulation of lipid biosynthetic process|",protein binding|protein homodimerization activity|,10,0,0,10,0.3,0.458,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000073530,PAPPA2,pappalysin 2,extracellular vesicular exosome|,proteolysis|bone morphogenesis|,metalloendopeptidase activity|metallopeptidase activity|,10,0,0,10,0.1,0.109,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000032280,TLE3,"transducin-like enhancer of split 3, homolog of Drosophila E(spl)",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|Wnt signaling pathway|cell differentiation|",protein binding|,10,-0.1,0.153,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000042594,SH2B3,SH2B adaptor protein 3,intracellular|,hemopoiesis|cell differentiation|embryonic hemopoiesis|embryonic hemopoiesis|intracellular signal transduction|,signal transducer activity|protein binding|,10,-0.1,0.214,10,0,0,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000033569,BAI3,brain-specific angiogenesis inhibitor 3,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|negative regulation of angiogenesis|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|,10,0,0,10,-0.1,0.285,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000022894,ADAMTS5,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)",extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|defense response to bacterium|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000020163,UQCR11,"ubiquinol-cytochrome c reductase, complex III subunit XI",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|respiratory chain|,transport|oxidation-reduction process|hydrogen ion transmembrane transport|,ubiquinol-cytochrome-c reductase activity|electron carrier activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000030322,MBD4,methyl-CpG binding domain protein 4,chromatin|intracellular|nucleus|nucleus|cytoplasm|,DNA repair|base-excision repair|DNA methylation|cellular response to DNA damage stimulus|mitotic G2 DNA damage checkpoint|intrinsic apoptotic signaling pathway in response to DNA damage|response to radiation|,purine-specific mismatch base pair DNA N-glycosylase activity|DNA binding|catalytic activity|uracil DNA N-glycosylase activity|pyrimidine-specific mismatch base pair DNA N-glycosylase activity|hydrolase activity|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA-3-methylbase glycosylase activity|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|,10,0.6,0.162,10,-0.7,0.643,0,0,0,0.871,0,0,-1.8,1.6
ENSMUSG00000034771,TLE2,"transducin-like enhancer of split 2, homolog of Drosophila E(spl)",extracellular space|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Wnt signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of canonical Wnt signaling pathway|",transcription corepressor activity|,10,0,0,10,-0.3,0.312,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000039086,SS18L1,synovial sarcoma translocation gene on chromosome 18-like 1,"chromosome, centromeric region|kinetochore|condensed nuclear chromosome, centromeric region|nucleus|chromosome|nuclear body|nBAF complex|","transcription, DNA-templated|regulation of transcription, DNA-templated|dendrite development|chromatin modification|positive regulation of transcription, DNA-templated|regulation of dendrite development|positive regulation of dendrite morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.1,0.126,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000029027,DFFB,"DNA fragmentation factor, beta subunit",nuclear chromatin|nuclear chromatin|intracellular|nucleus|cytoplasm|cytosol|,apoptotic DNA fragmentation|apoptotic DNA fragmentation|apoptotic process|apoptotic chromosome condensation|nucleic acid phosphodiester bond hydrolysis|,DNA binding|GPI-anchor transamidase activity|nuclease activity|deoxyribonuclease activity|deoxyribonuclease activity|protein binding|hydrolase activity|enzyme binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,9,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000018822,SFRP5,secreted frizzled-related sequence protein 5,extracellular region|cytoplasm|plasma membrane|,vasculature development|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|brain development|negative regulation of cell proliferation|gonad development|Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|negative regulation of catenin import into nucleus|post-anal tail morphogenesis|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of JUN kinase activity|digestive tract morphogenesis|negative regulation of protein kinase B signaling|convergent extension involved in axis elongation|canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|regulation of establishment of planar polarity|planar cell polarity pathway involved in neural tube closure|negative regulation of planar cell polarity pathway involved in axis elongation|negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis|,Wnt-protein binding|PDZ domain binding|Wnt-activated receptor activity|,10,0,0,10,-0.1,0.174,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000074277,PHLDB3,"pleckstrin homology-like domain, family B, member 3",cellular_component|,biological_process|,enzyme binding|,10,0.4,1.36,10,-0.2,1.19,0,0,0,0.871,0,0,-1,1.9
ENSMUSG00000031425,PLP1,proteolipid protein (myelin) 1,plasma membrane|membrane|integral component of membrane|myelin sheath|,inflammatory response|integrin-mediated signaling pathway|axon ensheathment|glial cell differentiation|positive regulation of gene expression|astrocyte development|central nervous system myelination|myelination|myelination|myelination|myelination|long-chain fatty acid biosynthetic process|cell maturation|axon development|,structural molecule activity|protein binding|structural constituent of myelin sheath|,10,0,0,10,0,0,0,0,0,0.871,0,0,-2,1.1
ENSMUSG00000043909,TRP53BP1,transformation related protein 53 binding protein 1,"chromosome, centromeric region|kinetochore|chromosome, telomeric region|nucleus|nucleus|replication fork|chromosome|cytoplasm|","DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II activating transcription factor binding|RNA polymerase II transcription cofactor activity|p53 binding|DNA binding|damaged DNA binding|protein binding|transcription factor binding|methylated histone binding|telomeric DNA binding|,10,0,0,10,0.1,0.0995,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000061533,CEP128,centrosomal protein 128,spindle pole|cytoplasm|centriole|microtubule organizing center|cytoskeleton|,biological_process|,molecular_function|,10,0.6,0.532,10,0,0,0,0,0,0.871,0,0,-0.8,2
ENSMUSG00000037795,N4BP2,NEDD4 binding protein 2,cytosol|,phosphorylation|nucleic acid phosphodiester bond hydrolysis|,endonuclease activity|protein binding|ATP binding|ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000017119,NBR1,neighbor of Brca1 gene 1,pre-autophagosomal structure|cytoplasm|lysosome|late endosome|autophagic vacuole|cytosol|membrane|cytoplasmic vesicle|extracellular vesicular exosome|,macroautophagy|regulation of bone mineralization|regulation of stress-activated MAPK cascade|negative regulation of osteoblast differentiation|protein oligomerization|,protein binding|zinc ion binding|ubiquitin binding|metal ion binding|mitogen-activated protein kinase binding|,9,0,0,9,-0.1,0.392,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000019489,CD70,CD70 antigen,extracellular space|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,immune response|extrinsic apoptotic signaling pathway|,protease binding|cytokine activity|tumor necrosis factor receptor binding|,10,0.1,0.0589,10,0,0,0,0,0,0.871,0,0,-1.8,1.1
ENSMUSG00000023830,IGF2R,insulin-like growth factor 2 receptor,extracellular space|nucleus|nuclear envelope lumen|cytoplasm|lysosome|endosome|late endosome|trans-Golgi network|plasma membrane|cell surface|membrane|membrane|integral component of membrane|clathrin coat|endocytic vesicle|trans-Golgi network transport vesicle|perinuclear region of cytoplasm|extracellular vesicular exosome|,liver development|transport|G-protein coupled receptor signaling pathway|response to retinoic acid|regulation of apoptotic process|positive regulation of apoptotic process|,glycoprotein binding|glycoprotein binding|G-protein alpha-subunit binding|retinoic acid binding|G-protein coupled receptor activity|transporter activity|insulin-like growth factor binding|mannose binding|enzyme binding|insulin-like growth factor II binding|identical protein binding|phosphoprotein binding|,10,-0.2,0.333,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000058833,2810428I15RIK,RIKEN cDNA 2810428I15 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000049502,DTX3L,deltex 3-like (Drosophila),nucleus|cytoplasm|,DNA repair|double-strand break repair|cellular response to DNA damage stimulus|histone monoubiquitination|chromatin modification|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|histone binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.2,0.0835,0,0,0,0.871,0,0,-1.4,1.6
ENSMUSG00000058488,KL,klotho,extracellular region|extracellular space|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,acute inflammatory response|carbohydrate metabolic process|energy reserve metabolic process|aging|aging|metabolic process|insulin receptor signaling pathway|fibroblast growth factor receptor signaling pathway|positive regulation of bone mineralization|calcium ion homeostasis|positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-glucuronidase activity|signal transducer activity|fibroblast growth factor receptor binding|protein binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|fibroblast growth factor binding|fibroblast growth factor binding|",10,0,0,10,0,0,0,0,0,0.871,0,0,-2,1
ENSMUSG00000096458,MOAP1,modulator of apoptosis 1,nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|cytosol|,protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|apoptotic process|apoptotic process|extrinsic apoptotic signaling pathway via death domain receptors|intrinsic apoptotic signaling pathway in response to DNA damage|regulation of apoptotic process|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of release of cytochrome c from mitochondria|apoptotic signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|,ubiquitin protein ligase binding|,10,0,0,9,-0.2,0.91,0,0,0,0.871,0,0,-1.6,1.3
ENSMUSG00000048806,IFNB1,"interferon beta 1, fibroblast",extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|B cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|positive regulation of peptidyl-serine phosphorylation of STAT protein|cellular response to interferon-beta|B cell proliferation|B cell proliferation|defense response to bacterium|response to exogenous dsRNA|response to exogenous dsRNA|negative regulation of viral genome replication|innate immune response|regulation of MHC class I biosynthetic process|negative regulation of T cell differentiation|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|type I interferon signaling pathway|negative regulation of T-helper 2 cell cytokine production|positive regulation of apoptotic signaling pathway|,cytokine activity|cytokine activity|cytokine receptor binding|type I interferon receptor binding|,10,1.4,2,10,0,0,0,0,0,0.871,0,0,-0.7,3
ENSMUSG00000019846,LAMA4,"laminin, alpha 4",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basal lamina|laminin-1 complex|extracellular vesicular exosome|,blood vessel development|cell adhesion|regulation of cell adhesion|regulation of cell migration|regulation of embryonic development|brown fat cell differentiation|,receptor binding|,10,-0.1,0.0437,10,0,0,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000020520,GALNT10,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10,Golgi apparatus|membrane|integral component of membrane|,protein O-linked glycosylation|,"polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000067702,TUBA3A,"tubulin, alpha 3A",nucleus|microtubule|cilium|ciliary basal body|,None,None,10,0,0,10,-0.1,0.355,0,0,0,0.871,0,0,-1.4,1.5
ENSMUSG00000039126,PRUNE2,prune homolog 2 (Drosophila),cytoplasm|,apoptotic process|,molecular_function|pyrophosphatase activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000091002,TCERG1L,transcription elongation regulator 1-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.646,0,0,0,0.871,0,0,-0.9,2
ENSMUSG00000003190,BCL2L12,BCL2-like 12 (proline rich),nucleus|membrane|,apoptotic process|regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|inhibition of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of cellular senescence|,p53 binding|,10,0,0,10,0.4,0.66,0,0,0,0.871,0,0,-1,1.8
ENSMUSG00000037321,TAP1,"transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)",extracellular region|mitochondrion|endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|TAP complex|intracellular membrane-bounded organelle|host cell|,immune system process|ATP catabolic process|ATP catabolic process|transport|defense response|protein transport|peptide transport|intracellular transport of viral protein in host cell|antigen processing and presentation of endogenous peptide antigen via MHC class I|protection from natural killer cell mediated cytotoxicity|cytosol to ER transport|transmembrane transport|,"nucleotide binding|transporter activity|ATP binding|peptide transporter activity|peptide transporter activity|ATPase activity|MHC class Ib protein binding|MHC class I protein binding|MHC class I protein binding|peptide antigen binding|ATPase activity, coupled to transmembrane movement of substances|protein homodimerization activity|ADP binding|TAP1 binding|TAP2 binding|tapasin binding|protein heterodimerization activity|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000002249,TEAD3,TEA domain family member 3,intracellular|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|hippo signaling|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription factor binding|DNA binding|sequence-specific DNA binding transcription factor activity|,10,0,0,10,0.3,0.0873,0,0,0,0.871,0,0,-1,2
ENSMUSG00000016477,E2F3,E2F transcription factor 3,nucleus|transcription factor complex|cytoplasm|Golgi apparatus|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|positive regulation of cell proliferation|positive regulation of transcription, DNA-templated|",core promoter binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0,0,10,-0.2,0.684,0,0,0,0.871,0,0,-1.6,1.4
ENSMUSG00000029636,WASF3,"WAS protein family, member 3",cytoplasm|cytoskeleton|lamellipodium|,cytoskeleton organization|regulation of cell shape|oligodendrocyte development|lamellipodium assembly|actin cytoskeleton organization|positive regulation of myelination|positive regulation of myelination|,molecular_function|actin binding|,10,0,0,10,-0.1,0.166,0,0,0,0.871,0,0,-1.7,1.3
ENSMUSG00000037035,INHBB,inhibin beta-B,extracellular region|perinuclear region of cytoplasm|,eye development|response to mechanical stimulus|activin receptor signaling pathway|growth|negative regulation of insulin secretion|positive regulation of follicle-stimulating hormone secretion|negative regulation of follicle-stimulating hormone secretion|negative regulation of hepatocyte growth factor biosynthetic process|oocyte development|positive regulation of ovulation|cellular response to cholesterol|positive regulation of apoptotic signaling pathway|,hormone activity|growth factor activity|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.7,1.4
ENSMUSG00000024032,TFF1,trefoil factor 1,extracellular region|extracellular space|cytoplasm|,negative regulation of cell proliferation|response to wounding|cell differentiation|response to estradiol|,protein binding|growth factor activity|,10,0,0,10,-0.1,0.00262,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000031880,RRAD,Ras-related associated with diabetes,plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|negative regulation of cell growth|,nucleotide binding|protein binding|calmodulin binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000052914,CYP2J6,"cytochrome P450, family 2, subfamily j, polypeptide 6",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,retinoid metabolic process|arachidonic acid metabolic process|epoxygenase P450 pathway|linoleic acid metabolic process|oxidation-reduction process|,"NADPH-hemoprotein reductase activity|monooxygenase activity|iron ion binding|arachidonic acid epoxygenase activity|arachidonic acid 14,15-epoxygenase activity|arachidonic acid 11,12-epoxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|metal ion binding|aromatase activity|linoleic acid epoxygenase activity|",10,-0.5,0.177,10,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000031142,CACNA1F,"calcium channel, voltage-dependent, alpha 1F subunit",photoreceptor outer segment|plasma membrane|voltage-gated calcium channel complex|membrane|integral component of membrane|neuronal cell body|perikaryon|,transport|ion transport|calcium ion transport|cellular calcium ion homeostasis|axonogenesis|visual perception|visual perception|regulation of ion transmembrane transport|dendrite morphogenesis|response to stimulus|detection of light stimulus involved in visual perception|transmembrane transport|retina development in camera-type eye|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|high voltage-gated calcium channel activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.1,2
ENSMUSG00000021222,DCAF4,DDB1 and CUL4 associated factor 4,Cul4-RING E3 ubiquitin ligase complex|,biological_process|,molecular_function|,10,-0.1,0.165,10,0,0,0,0,0,0.871,0,0,-1.2,1.7
ENSMUSG00000020661,DNMT3A,DNA methyltransferase 3A,"chromosome, centromeric region|euchromatin|heterochromatin|nucleus|nucleus|nuclear heterochromatin|cytoplasm|cytoplasm|nuclear matrix|","negative regulation of transcription from RNA polymerase II promoter|DNA methylation|DNA methylation|DNA methylation|methylation-dependent chromatin silencing|methylation-dependent chromatin silencing|regulation of gene expression by genetic imprinting|regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|maintenance of DNA methylation|DNA methylation on cytosine within a CG sequence|chromatin modification|methylation|DNA methylation involved in embryo development|DNA methylation involved in gamete generation|hypermethylation of CpG island|S-adenosylhomocysteine metabolic process|S-adenosylmethioninamine metabolic process|cellular response to amino acid stimulus|C-5 methylation of cytosine|C-5 methylation of cytosine|","DNA binding|DNA binding|chromatin binding|DNA (cytosine-5-)-methyltransferase activity|DNA (cytosine-5-)-methyltransferase activity|DNA (cytosine-5-)-methyltransferase activity|protein binding|methyltransferase activity|transferase activity|unmethylated CpG binding|metal ion binding|DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates|",10,0.1,0.0502,10,0,0,0,0,0,0.871,0,0,-1.5,1.4
ENSMUSG00000037679,INF2,"inverted formin, FH2 and WH2 domain containing",nucleus|cytoplasm|endoplasmic reticulum|perinuclear region of cytoplasm|,cellular component organization|actin cytoskeleton organization|regulation of cellular component size|regulation of mitochondrial fission|,actin binding|Rho GTPase binding|,9,0,0,9,0,0,0,0,0,0.871,0,0,-1.6,1.6
ENSMUSG00000072919,NOXRED1,NADP+ dependent oxidoreductase domain containing 1,cellular_component|,proline biosynthetic process|oxidation-reduction process|,molecular_function|pyrroline-5-carboxylate reductase activity|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.1,0.116,10,0,0,0,0,0,0.871,0,0,-1.3,1.7
ENSMUSG00000050357,RLTPR,"RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing",immunological synapse|cytoplasm|cell-cell junction|F-actin capping protein complex|membrane|,positive regulation of interferon-gamma production|positive regulation of T cell proliferation|establishment of protein localization|positive regulation of regulatory T cell differentiation|thymus development|homeostasis of number of cells|T cell receptor signaling pathway|positive regulation of interleukin-2 secretion|positive regulation of interferon-gamma secretion|,protein binding|,10,-0.2,0.474,10,0.1,0.566,0,0,0,0.871,0,0,-1.7,1.2
ENSMUSG00000027611,PROCR,"protein C receptor, endothelial",centrosome|membrane|integral component of membrane|extracellular vesicular exosome|,immune response|blood coagulation|hemostasis|antigen processing and presentation|negative regulation of coagulation|negative regulation of coagulation|,protein C-terminus binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.6
ENSMUSG00000029119,MAN2B2,"mannosidase 2, alpha B2",extracellular region|lysosome|extracellular vesicular exosome|,carbohydrate metabolic process|mannose metabolic process|metabolic process|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-mannosidase activity|zinc ion binding|mannosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|metal ion binding|",10,0,0,10,0,0,0,0,0,0.871,0,0,-1.6,1.5
ENSMUSG00000002083,BBC3,BCL2 binding component 3,intracellular|mitochondrion|mitochondrion|mitochondrial envelope|endoplasmic reticulum|,release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cellular response to DNA damage stimulus|determination of adult lifespan|negative regulation of cell growth|positive regulation of protein homooligomerization|negative regulation of endoplasmic reticulum calcium ion concentration|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of apoptotic process|positive regulation of neuron apoptotic process|negative regulation of growth|negative regulation of growth|release of sequestered calcium ion into cytosol|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|positive regulation of thymocyte apoptotic process|cellular response to ionizing radiation|intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of release of cytochrome c from mitochondria|apoptotic signaling pathway|execution phase of apoptosis|execution phase of apoptosis|positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|positive regulation of cysteine-type endopeptidase activity|positive regulation of intrinsic apoptotic signaling pathway|,protein binding|,10,0,0,10,-0.2,0.276,0,0,0,0.871,0,0,-1.6,1.3
ENSMUSG00000059824,DBP,D site albumin promoter binding protein,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|circadian rhythm|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.8,1.2
ENSMUSG00000066515,KLK1B3,kallikrein 1-related peptidase b3,nucleus|,proteolysis|intracellular signal transduction|,catalytic activity|serine-type endopeptidase activity|receptor signaling protein activity|growth factor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1.5,1.5
ENSMUSG00000046532,AR,androgen receptor,nuclear chromatin|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|axon|dendrite|protein complex|,"in utero embryonic development|regulation of systemic arterial blood pressure|epithelial cell morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|spermatogenesis|single fertilization|positive regulation of cell proliferation|male gonad development|male gonad development|fertilization|cellular process|regulation of gene expression|male somatic sex determination|androgen receptor signaling pathway|androgen receptor signaling pathway|intracellular receptor signaling pathway|positive regulation of intracellular estrogen receptor signaling pathway|Leydig cell differentiation|multicellular organism growth|positive regulation of phosphorylation|steroid hormone mediated signaling pathway|positive regulation of MAPK cascade|positive regulation of insulin-like growth factor receptor signaling pathway|negative regulation of integrin biosynthetic process|positive regulation of integrin biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase III promoter|male sex differentiation|reproductive structure development|regulation of developmental growth|organ formation|male genitalia morphogenesis|negative regulation of epithelial cell proliferation|regulation of catalytic activity|positive regulation of NF-kappaB transcription factor activity|protein oligomerization|activation of prostate induction by androgen receptor signaling pathway|morphogenesis of an epithelial fold|lateral sprouting involved in mammary gland duct morphogenesis|regulation of prostatic bud formation|prostate gland growth|prostate gland epithelium morphogenesis|epithelial cell differentiation involved in prostate gland development|tertiary branching involved in mammary gland duct morphogenesis|mammary gland alveolus development|reproductive system development|seminiferous tubule development|seminiferous tubule development|regulation of establishment of protein localization to plasma membrane|negative regulation of extrinsic apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|androgen receptor activity|androgen receptor activity|receptor binding|steroid binding|androgen binding|protein binding|beta-catenin binding|transcription factor binding|zinc ion binding|lipid binding|enzyme binding|enzyme binding|protein domain specific binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|androgen receptor binding|POU domain binding|,10,0,0,10,0,0,0,0,0,0.871,0,0,-1,2
ENSMUSG00000035896,RNASE1,"ribonuclease, RNase A family, 1 (pancreatic)",extracellular region|extracellular vesicular exosome|,None,nucleic acid binding|nuclease activity|endonuclease activity|pancreatic ribonuclease activity|hydrolase activity|,10,0,0,10,0.8,0.247,0,0,0,0.871,0,0,-1.5,1.7
ENSMUSG00000021102,GLRX5,glutaredoxin 5 homolog (S. cerevisiae),nucleus|mitochondrion|mitochondrion|,biological_process|cell redox homeostasis|,"molecular_function|electron carrier activity|protein disulfide oxidoreductase activity|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,2,180,10,2.4,164,2.4,342,342,1.00E-05,1,1,1.9,2.8
ENSMUSG00000033216,EEFSEC,"eukaryotic elongation factor, selenocysteine-tRNA-specific",nucleus|cytoplasm|mitochondrion|ribonucleoprotein complex|,selenocysteine incorporation|selenocysteine incorporation|GTP catabolic process|translation|translational elongation|,tRNA binding|nucleotide binding|translation elongation factor activity|GTPase activity|protein binding|GTP binding|selenocysteine insertion sequence binding|ribonucleoprotein complex binding|,10,3.3,139,10,3.9,152,3.8,289,289,1.00E-05,1,1,3.2,4.7
ENSMUSG00000078517,EMC1,ER membrane protein complex subunit 1,membrane|integral component of membrane|ER membrane protein complex|,biological_process|,molecular_function|,10,1.7,149,10,2,116,1.9,263,263,1.00E-05,1,1,1.5,2.4
ENSMUSG00000027131,EMC4,ER membrane protein complex subunit 4,membrane|integral component of membrane|ER membrane protein complex|,apoptotic process|biological_process|,molecular_function|,10,1.5,132,10,2.1,74.5,1.6,206,206,1.00E-05,1,1,1.3,2.2
ENSMUSG00000022711,PMM2,phosphomannomutase 2,cytoplasm|neuronal cell body|extracellular vesicular exosome|,metabolic process|mannose biosynthetic process|,catalytic activity|phosphomannomutase activity|isomerase activity|,10,2.1,102,10,1.6,99,2,199,199,1.00E-05,1,1,1.6,2.5
ENSMUSG00000020744,SLC25A19,"solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19",nucleus|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|transmembrane transport|,None,9,2.6,115,9,2.3,83.7,2.4,198,198,1.00E-05,1,1,2.1,3.3
ENSMUSG00000052533,NUP188,nucleoporin 188,nucleus|nuclear pore|membrane|,transport|protein transport|mRNA transport|,None,6,2.2,126,6,1.8,39.4,2.1,164,164,1.00E-05,1,1,1.6,2.9
ENSMUSG00000040565,BTAF1,"BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae)",cellular_component|,negative regulation of chromatin binding|,molecular_function|,9,2.4,77.4,9,2,65.7,2.3,141,141,1.00E-05,1,1,1.7,2.9
ENSMUSG00000026112,COA5,cytochrome C oxidase assembly factor 5,mitochondrion|mitochondrion|,biological_process|,molecular_function|,10,2.4,83.2,10,2.4,46.3,2.4,129,129,2.00E-05,1,1,1.7,3.1
ENSMUSG00000029911,SSBP1,single-stranded DNA binding protein 1,nucleus|mitochondrion|mitochondrion|mitochondrial nucleoid|extracellular vesicular exosome|,DNA replication|positive regulation of helicase activity|mitochondrion morphogenesis|,DNA binding|chromatin binding|single-stranded DNA binding|poly(A) RNA binding|,9,1.5,109,9,1.2,16.8,1.4,123,123,2.00E-05,1,1,1.1,1.9
ENSMUSG00000059811,ATL2,atlastin GTPase 2,endoplasmic reticulum|membrane|membrane|integral component of membrane|,endoplasmic reticulum organization|Golgi organization|protein homooligomerization|,nucleotide binding|GTPase activity|protein binding|GTP binding|hydrolase activity|identical protein binding|,10,1.4,94.2,10,1.4,19,1.4,113,113,2.00E-05,1,1,1.1,1.8
ENSMUSG00000024668,SDHAF2,succinate dehydrogenase complex assembly factor 2,mitochondrion|mitochondrion|,"mitochondrial electron transport, succinate to ubiquinone|protein dephosphorylation|protein dephosphorylation|negative regulation of epithelial to mesenchymal transition|negative regulation of epithelial to mesenchymal transition|protein-FAD linkage|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|",molecular_function|,10,1.1,61.5,10,3.3,58.7,2,110,110,2.00E-05,1,1,1.9,3.8
ENSMUSG00000032872,CYB5R4,cytochrome b5 reductase 4,cell|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|perinuclear region of cytoplasm|,generation of precursor metabolites and energy|NADP metabolic process|superoxide metabolic process|insulin secretion|heme metabolic process|glucose homeostasis|response to antibiotic|cell development|oxidation-reduction process|oxidation-reduction process|,"NADPH-hemoprotein reductase activity|cytochrome-b5 reductase activity, acting on NAD(P)H|cytochrome-b5 reductase activity, acting on NAD(P)H|cytochrome-b5 reductase activity, acting on NAD(P)H|protein binding|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor|heme binding|heme binding|metal ion binding|flavin adenine dinucleotide binding|",10,1.6,59,10,2,52.9,1.9,110,110,2.00E-05,1,1,1.4,2.8
ENSMUSG00000009470,TNPO1,transportin 1,nucleus|cytoplasm|,transport|intracellular protein transport|protein transport|,protein binding|Ran GTPase binding|poly(A) RNA binding|,10,1.5,81.3,10,1.5,23.4,1.5,104,104,2.00E-05,1,1,1,1.9
ENSMUSG00000046909,TEFM,"transcription elongation factor, mitochondrial",mitochondrion|mitochondrial matrix|ribonucleoprotein complex|mitochondrial nucleoid|,"oxidative phosphorylation|DNA metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from mitochondrial promoter|regulation of catalytic activity|",DNA polymerase processivity factor activity|poly(A) RNA binding|,10,1.8,54.5,10,2.5,49.8,2.5,101,101,3.00E-05,1,1,1.7,3.9
ENSMUSG00000020790,ANKFY1,ankyrin repeat and FYVE domain containing 1,cytoplasm|lysosomal membrane|endosome|endosome membrane|membrane|extracellular vesicular exosome|,endocytosis|,metal ion binding|,10,1.1,44.5,10,1.9,60.9,1.8,101,101,3.00E-05,1,1,1.1,2.4
ENSMUSG00000022856,TMEM41A,transmembrane protein 41a,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1,50.8,10,1.4,44.6,1.3,93,93,3.00E-05,1,1,1,1.7
ENSMUSG00000061904,SLC25A3,"solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|,symporter activity|protein complex binding|,9,1.5,80.8,9,-1.6,22.7,1.5,83.9,83.9,8.00E-05,1,1,1.1,2.3
ENSMUSG00000022889,MRPL39,mitochondrial ribosomal protein L39,mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,mitochondrial genome maintenance|translation|,nucleotide binding|structural constituent of ribosome|poly(A) RNA binding|,10,1.3,74.2,10,0.7,8.3,1.2,80.6,80.6,0.00017,1,1,1,1.8
ENSMUSG00000052146,RPS10,ribosomal protein S10,nucleus|nucleolus|cytoplasm|ribosome|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,None,structural constituent of ribosome|poly(A) RNA binding|,9,1.8,72.3,9,1.2,2.33,1.7,72.9,72.9,0.00052,1,1,1.2,2.8
ENSMUSG00000027176,CSTF3,"cleavage stimulation factor, 3' pre-RNA, subunit 3",intracellular|nucleus|,RNA processing|mRNA processing|,poly(A) RNA binding|,10,0.8,25.9,10,2,55.1,1.8,72.8,72.8,0.00054,1,1,0.8,2.4
ENSMUSG00000020530,GGNBP2,gametogenetin binding protein 2,nucleus|cytoplasm|cytoplasmic vesicle|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,protein binding|,10,2.1,68.2,10,0.8,10.7,1.9,71.9,71.9,0.00054,1,1,1.1,2.5
ENSMUSG00000042323,PBRM1,polybromo 1,kinetochore|nucleus|,"placenta development|blood vessel remodeling|heart morphogenesis|epicardium-derived cardiac endothelial cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|negative regulation of cell proliferation|chromatin modification|positive regulation of transcription, DNA-templated|cardiac vascular smooth muscle cell development|vasculogenesis involved in coronary vascular morphogenesis|",DNA binding|chromatin binding|protein binding|,10,0.9,28.1,10,1.5,47.7,1.1,71.6,71.6,0.00057,1,1,0.8,1.7
ENSMUSG00000017715,PGS1,phosphatidylglycerophosphate synthase 1,mitochondrion|endoplasmic reticulum|,lipid metabolic process|biological_process|metabolic process|phospholipid biosynthetic process|,"nucleotide binding|molecular_function|catalytic activity|ATP binding|CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity|transferase activity|phosphotransferase activity, for other substituted phosphate groups|",10,1.7,59.4,10,0.8,13.8,1.6,71.4,71.4,0.00058,1,1,0.9,2.1
ENSMUSG00000030316,TAMM41,"TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)",mitochondrion|,transport|biological_process|protein transport|,molecular_function|,10,1.3,64.9,10,0.8,6.83,1,70.4,70.4,0.00061,1,1,0.8,1.7
ENSMUSG00000052395,RFT1,RFT1 homolog (S. cerevisiae),cellular_component|membrane|integral component of membrane|,transport|lipid transport|carbohydrate transport|,molecular_function|lipid transporter activity|,8,1.5,68,7,0.8,2.2,1.4,67.9,67.9,0.00066,1,1,1,2.4
ENSMUSG00000062647,RPL7A,ribosomal protein L7A,nucleus|membrane|cytosolic large ribosomal subunit|polysomal ribosome|extracellular vesicular exosome|,None,poly(A) RNA binding|,4,1.4,60.3,4,1.1,7.58,1.4,66.6,66.6,0.0007,1,1,1.1,2
ENSMUSG00000007646,RAD51C,RAD51 homolog C,nucleus|replication fork|cytoplasm|mitochondrion|Rad51B-Rad51C-Rad51D-XRCC2 complex|Rad51C-XRCC3 complex|perinuclear region of cytoplasm|Holliday junction resolvase complex|Holliday junction resolvase complex|,"double-strand break repair via homologous recombination|DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|DNA metabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|female meiosis sister chromatid cohesion|reciprocal meiotic recombination|male meiosis I|spermatogenesis|positive regulation of G2/M transition of mitotic cell cycle|",nucleotide binding|four-way junction DNA binding|DNA binding|ATP binding|DNA-dependent ATPase activity|crossover junction endodeoxyribonuclease activity|crossover junction endodeoxyribonuclease activity|,10,1.4,25.3,10,1.7,41.6,1.5,65.9,65.9,0.0007,1,1,1.2,2.6
ENSMUSG00000023939,MRPL14,mitochondrial ribosomal protein L14,mitochondrion|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,1.3,28.1,10,1.5,36.5,1.3,64.2,64.2,0.00077,1,1,1,2.1
ENSMUSG00000040675,MTHFD1L,methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like,mitochondrion|mitochondrion|membrane|,one-carbon metabolic process|folic acid-containing compound metabolic process|10-formyltetrahydrofolate biosynthetic process|folic acid-containing compound biosynthetic process|formate metabolic process|tetrahydrofolate metabolic process|oxidation-reduction process|,nucleotide binding|catalytic activity|formate-tetrahydrofolate ligase activity|formate-tetrahydrofolate ligase activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|ATP binding|ligase activity|protein homodimerization activity|,10,1.2,55.4,10,0.5,7.4,1,60.6,60.6,0.00094,1,1,0.6,1.5
ENSMUSG00000020843,TIMM22,translocase of inner mitochondrial membrane 22,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|protein transport|,protein binding|,10,0.9,24.9,10,1.7,36.6,1.2,59.7,59.7,0.00101,1,1,0.8,2
ENSMUSG00000034022,CPSF1,cleavage and polyadenylation specific factor 1,nucleus|mRNA cleavage and polyadenylation specificity factor complex|,mRNA polyadenylation|mRNA cleavage|mRNA processing|,nucleic acid binding|RNA binding|mRNA 3'-UTR binding|,7,1.3,31.5,5,1.7,28.5,1.3,58,58,0.00119,1,1,0.9,2.6
ENSMUSG00000030704,RAB6A,"RAB6A, member RAS oncogene family",intracellular|cell|Golgi apparatus|Golgi apparatus|trans-Golgi network|cytosol|membrane|cytoplasmic vesicle|extracellular vesicular exosome|,protein targeting to Golgi|GTP catabolic process|transport|intracellular protein transport|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|peptidyl-cysteine methylation|antigen processing and presentation|positive regulation of ATPase activity|protein localization to Golgi apparatus|,nucleotide binding|ATPase activator activity|GTPase activity|protein binding|GTP binding|protein domain specific binding|ATPase binding|,10,-1.3,28.3,10,-1.4,29.2,-1.3,57.1,-57.1,0.00141,1,1,-2.3,-0.9
ENSMUSG00000025208,MRPL43,mitochondrial ribosomal protein L43,mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,9,2.2,27.7,10,1.8,30.1,2.1,56.5,56.5,0.00147,1,1,1.5,3.4
ENSMUSG00000002984,TOMM40,translocase of outer mitochondrial membrane 40 homolog (yeast),mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane translocase complex|membrane|integral component of membrane|integral component of mitochondrial outer membrane|integral component of mitochondrial membrane|pore complex|extracellular vesicular exosome|,protein targeting to mitochondrion|transport|ion transport|protein transport|transmembrane transport|protein transmembrane transport|,protein transmembrane transporter activity|porin activity|,8,1.1,42.4,8,1.4,14.6,1.2,56.3,56.3,0.00153,1,1,0.8,1.8
ENSMUSG00000021023,1110008L16RIK,RIKEN cDNA 1110008L16 gene,cellular_component|mitochondrion|,tRNA processing|biological_process|,molecular_function|,10,1.4,47.2,10,0.8,10.5,1.2,56.2,56.2,0.00154,1,1,0.8,1.8
ENSMUSG00000031708,TECR,"trans-2,3-enoyl-CoA reductase",nucleus|cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,lipid metabolic process|steroid biosynthetic process|fatty acid elongation|very long-chain fatty acid biosynthetic process|oxidation-reduction process|,"oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|",10,0.9,36.8,10,0.9,19.4,0.9,55.8,55.8,0.00163,1,1,0.7,1.2
ENSMUSG00000030286,EMC3,ER membrane protein complex subunit 3,membrane|integral component of membrane|ER membrane protein complex|,biological_process|,molecular_function|,10,1.1,50.7,10,0.7,7.29,0.8,55.3,55.3,0.00177,1,1,0.6,1.5
ENSMUSG00000090247,BLOC1S1,"biogenesis of lysosomal organelles complex-1, subunit 1",extracellular space|intracellular|cell|cytoplasm|mitochondrion|mitochondrial intermembrane space|mitochondrial intermembrane space|mitochondrial matrix|mitochondrial matrix|cytosol|cytosol|BLOC-1 complex|BLOC-1 complex|extracellular vesicular exosome|,anterograde axon cargo transport|aerobic respiration|peptidyl-lysine acetylation|neuron projection development|anterograde synaptic vesicle transport|,protein binding|,10,2.2,49.2,10,1.3,7.86,2,53.9,53.9,0.00222,0,1,1.2,3
ENSMUSG00000023967,MRPS18A,mitochondrial ribosomal protein S18A,intracellular|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|biological_process|,molecular_function|structural constituent of ribosome|,10,1.4,26.9,10,1.7,28.2,1.4,53.9,53.9,0.00222,0,1,0.8,2.5
ENSMUSG00000005354,TXN2,thioredoxin 2,nucleolus|mitochondrion|mitochondrion|dendrite|neuronal cell body|,glycerol ether metabolic process|transport|cell redox homeostasis|oxidation-reduction process|,peptide-methionine (S)-S-oxide reductase activity|protein disulfide oxidoreductase activity|protein complex binding|peptide-methionine (R)-S-oxide reductase activity|,10,1.9,29.9,10,1.8,24.4,1.8,53.8,53.8,0.00223,0,1,1.3,3.2
ENSMUSG00000028247,COQ3,"coenzyme Q3 homolog, methyltransferase (yeast)",mitochondrion|,glycerol metabolic process|ubiquinone biosynthetic process|methylation|,"hexaprenyldihydroxybenzoate methyltransferase activity|methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|3-demethylubiquinone-9 3-O-methyltransferase activity|transferase activity|",10,1.2,49.4,10,0.6,4.12,1.2,52.9,52.9,0.00261,0,1,0.8,1.8
ENSMUSG00000031068,GLRX3,glutaredoxin 3,cytoplasm|Z disc|extracellular vesicular exosome|,regulation of the force of heart contraction|negative regulation of cardiac muscle hypertrophy|cell redox homeostasis|,protein kinase C binding|protein binding|electron carrier activity|protein disulfide oxidoreductase activity|poly(A) RNA binding|metal ion binding|iron-sulfur cluster binding|,10,0.8,30.1,10,1.6,24.5,0.8,52.7,52.7,0.00268,0,1,0.6,1.5
ENSMUSG00000020549,ELAC2,elaC homolog 2 (E. coli),nucleus|mitochondrion|mitochondrion|,"tRNA processing|mitochondrial tRNA 3'-trailer cleavage, endonucleolytic|",nuclease activity|endonuclease activity|hydrolase activity|poly(A) RNA binding|metal ion binding|,10,1.2,42.7,10,1,10.8,1.1,52.2,52.2,0.00296,0,1,0.6,1.6
ENSMUSG00000032044,RPUSD4,RNA pseudouridylate synthase domain containing 4,mitochondrion|,pseudouridine synthesis|RNA modification|,RNA binding|pseudouridine synthase activity|poly(A) RNA binding|,10,2.2,24.8,10,1.6,29.5,2.1,51.8,51.8,0.00313,0,1,1.4,3.3
ENSMUSG00000047459,DYNLRB1,dynein light chain roadblock-type 1,cytoplasm|centrosome|cytoskeleton|cytoplasmic dynein complex|microtubule|membrane|dynein complex|,transport|visual behavior|,motor activity|protein binding|identical protein binding|,9,1,41.9,10,1.2,10.7,1.1,51.3,51.3,0.00348,0,1,0.8,1.5
ENSMUSG00000029066,MRPL20,mitochondrial ribosomal protein L20,intracellular|mitochondrion|mitochondrial ribosome|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|rRNA binding|poly(A) RNA binding|,10,0.7,17.6,10,1.9,39.6,1.4,51,51,0.00361,0,1,0.7,2.1
ENSMUSG00000020544,COX11,cytochrome c oxidase assembly protein 11,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,negative regulation of glucokinase activity|,copper ion binding|protein binding|,8,1.2,33.9,8,1.1,15.7,1.1,49.1,49.1,0.00524,0,0,0.8,1.7
ENSMUSG00000045538,DDX28,DEAD (Asp-Glu-Ala-Asp) box polypeptide 28,nucleus|mitochondrion|mitochondrion|mitochondrial nucleoid|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,0.5,12.7,10,0.9,38.4,0.8,48.6,48.6,0.00575,0,0,0.4,1.4
ENSMUSG00000052428,TMCO1,transmembrane and coiled-coil domains 1,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-1.4,24.4,10,-1.6,23.3,-1.4,47.2,-47.2,0.00743,0,0,-2.8,-1.1
ENSMUSG00000028622,MRPL37,mitochondrial ribosomal protein L37,mitochondrion|mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|,10,1,33.1,10,1.4,14.6,1,47,47,0.00768,0,0,0.6,1.6
ENSMUSG00000038759,NUP205,nucleoporin 205,nuclear pore|membrane|nuclear membrane|nuclear periphery|,nuclear pore complex assembly|,structural constituent of nuclear pore|,8,1.8,33.8,8,1,16.7,1.6,46.9,46.9,0.00779,0,0,0.9,2.3
ENSMUSG00000049287,IBA57,"IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)",cytoplasm|mitochondrion|,glycine catabolic process|heme biosynthetic process|biological_process|,aminomethyltransferase activity|transferase activity|poly(A) RNA binding|,10,0.9,26.6,10,1.5,21.8,1,46.9,46.9,0.00779,0,0,0.6,1.7
ENSMUSG00000011254,THG1L,tRNA-histidine guanylyltransferase 1-like (S. cerevisiae),cytoplasm|mitochondrion|,tRNA modification|tRNA processing|protein homotetramerization|,nucleotide binding|magnesium ion binding|ATP binding|GTP binding|tRNA guanylyltransferase activity|transferase activity|nucleotidyltransferase activity|identical protein binding|metal ion binding|,9,1,44.4,10,0.5,5.12,1,45.3,45.3,0.0101,0,0,0.5,1.5
ENSMUSG00000067847,ROMO1,reactive oxygen species modulator 1,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,replicative cell aging|positive regulation of cell proliferation|cellular response to reactive oxygen species|defense response to bacterium|positive regulation of reactive oxygen species metabolic process|,molecular_function|,8,1.5,33.2,9,1.1,13.2,1.3,44.9,44.9,0.0108,0,0,0.8,2
ENSMUSG00000000884,GNB1L,"guanine nucleotide binding protein (G protein), beta polypeptide 1-like",cytoplasm|,social behavior|,molecular_function|,10,1.1,39.3,9,1.2,4.61,1.1,43.3,43.3,0.0124,0,0,0.8,1.7
ENSMUSG00000048118,ARID4A,AT rich interactive domain 4A (RBP1-like),nucleus|transcriptional repressor complex|,"regulation of gene expression by genetic imprinting|spermatogenesis|histone H4-K20 trimethylation|histone H4-K20 trimethylation|histone H3-K9 trimethylation|histone H3-K9 trimethylation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|erythrocyte development|histone H3-K4 trimethylation|establishment of Sertoli cell barrier|",None,10,0.8,32.6,10,0.7,10.5,0.8,42.3,42.3,0.0132,0,0,0.6,1.1
ENSMUSG00000028656,CAP1,"CAP, adenylate cyclase-associated protein 1 (yeast)",cytoplasm|plasma membrane|membrane|cortical actin cytoskeleton|extracellular vesicular exosome|,cell morphogenesis|ameboidal cell migration|receptor-mediated endocytosis|cytoskeleton organization|actin cytoskeleton organization|,actin binding|protein binding|,7,1.5,36.8,8,1.1,6.27,1.3,41.8,41.8,0.0136,0,0,0.8,2.2
ENSMUSG00000039001,RPS21,ribosomal protein S21,intracellular|cytoplasm|ribosome|small ribosomal subunit|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|,"endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|translation|translational elongation|ribosomal small subunit biogenesis|",structural constituent of ribosome|poly(A) RNA binding|protein N-terminus binding|,5,0.8,3.53,6,1.6,38.6,1.6,40.2,40.2,0.0148,0,0,0.8,2.5
ENSMUSG00000035772,MRPS2,mitochondrial ribosomal protein S2,intracellular|mitochondrion|ribosome|small ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,9,1.4,30.8,9,1.1,9.19,1.2,39.3,39.3,0.0155,0,0,0.7,1.8
ENSMUSG00000041747,UTP15,"UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)",nucleus|nucleolus|cytoplasm|,rRNA processing|biological_process|,poly(A) RNA binding|,9,0.7,13.7,8,2,28.4,0.8,39,39,0.0158,0,0,0.6,2.3
ENSMUSG00000059070,RPL18,ribosomal protein L18,intracellular|nucleus|nucleolus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,6,0.7,8.92,5,2,35.6,2,38.6,38.6,0.016,0,0,1.1,3.6
ENSMUSG00000020873,SLC35B1,"solute carrier family 35, member B1",endoplasmic reticulum|membrane|integral component of membrane|,transport|carbohydrate transport|transmembrane transport|,None,9,0.9,16.2,9,1.5,23.4,1,38.5,38.5,0.0161,0,0,0.6,1.9
ENSMUSG00000004100,PPAN,peter pan homolog (Drosophila),nucleus|,regulation of cell growth by extracellular stimulus|,poly(A) RNA binding|,8,0.9,19.9,9,1,17.9,1,37.3,37.3,0.0169,0,0,0.8,1.5
ENSMUSG00000050608,MINOS1,mitochondrial inner membrane organizing system 1,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.9,18.4,10,1.6,20.5,1.1,36.1,36.1,0.0179,0,0,0.7,2.4
ENSMUSG00000036376,ABT1,activator of basal transcription 1,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|spinal cord motor neuron differentiation|",nucleotide binding|DNA binding|RNA binding|poly(A) RNA binding|,9,0.5,8.79,8,1.6,31.3,0.8,36,36,0.0179,0,0,0.4,1.8
ENSMUSG00000001056,NHP2,NHP2 ribonucleoprotein,nucleus|nucleolus|cytoplasm|ribonucleoprotein complex|,rRNA processing|biological_process|ribosome biogenesis|,RNA binding|poly(A) RNA binding|,8,0.9,21.9,9,0.9,14.3,0.9,35.8,35.8,0.0181,0,0,0.7,1.4
ENSMUSG00000034880,MRPL34,mitochondrial ribosomal protein L34,intracellular|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,10,0.7,6.14,10,2.3,32.2,1,35.7,35.7,0.0182,0,0,0.9,2.9
ENSMUSG00000045128,RPL18A,ribosomal protein L18A,ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,3,-1.2,33,3,-0.6,4.2,-1.1,35.6,-35.6,0.0184,0,0,-2,-0.7
ENSMUSG00000032103,PUS3,pseudouridine synthase 3,cellular_component|nucleus|,pseudouridine synthesis|tRNA processing|RNA modification|tRNA pseudouridine synthesis|,RNA binding|pseudouridine synthase activity|isomerase activity|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|baruol synthase activity|,10,1,26.4,10,0.7,9.66,0.6,35.5,35.5,0.0184,0,0,0.4,1.2
ENSMUSG00000066232,IPO7,importin 7,intracellular|cell|nucleus|cytoplasm|membrane|,protein import into nucleus|transport|intracellular protein transport|protein transport|innate immune response|,protein binding|Ran GTPase binding|histone binding|,10,1.9,24.2,10,1,14.9,1.7,34.7,34.7,0.0193,0,0,1,2.6
ENSMUSG00000093904,TOMM20,translocase of outer mitochondrial membrane 20 homolog (yeast),mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial outer membrane|mitochondrial outer membrane translocase complex|membrane|integral component of membrane|ER-mitochondrion membrane contact site|,protein targeting|protein targeting to mitochondrion|transport|intracellular protein transport|protein transport|protein transmembrane transport|,P-P-bond-hydrolysis-driven protein transmembrane transporter activity|unfolded protein binding|,8,1.7,31.3,7,-2,23.7,1.5,34.7,34.7,0.0193,0,0,0.7,2.4
ENSMUSG00000087687,PET100,PET100 homolog (S. cerevisiae),cellular_component|mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.5,32.1,10,1.4,2.97,1.4,34.6,34.6,0.0194,0,0,0.8,2.5
ENSMUSG00000027384,NDUFAF5,"NADH dehydrogenase (ubiquinone) complex I, assembly factor 5",mitochondrion|mitochondrial inner membrane|membrane|extrinsic component of mitochondrial inner membrane|,metabolic process|methylation|mitochondrial respiratory chain complex I assembly|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.5,8.29,10,1,29.8,0.9,34.4,34.4,0.0196,0,0,0.6,1.3
ENSMUSG00000027706,SEC62,SEC62 homolog (S. cerevisiae),intracellular|cell|endoplasmic reticulum|membrane|integral component of membrane|,posttranslational protein targeting to membrane|transport|protein transport|,molecular_function|protein transporter activity|,10,2.1,35.1,10,0.5,4.6,2,33.2,33.2,0.0213,0,0,1.1,3.2
ENSMUSG00000037572,WDHD1,WD repeat and HMG-box DNA binding protein 1,"chromosome, centromeric region|nucleus|",RNA processing|regulation of chromosome organization|heterochromatin maintenance|,DNA binding|chromatin binding|RNA binding|protein binding|RNA polymerase binding|,10,1.5,31.5,10,0.9,3.41,1.3,33,33,0.0214,0,0,0.8,2.5
ENSMUSG00000029169,DHX15,DEAH (Asp-Glu-Ala-His) box polypeptide 15,nucleus|U12-type spliceosomal complex|U2-type post-mRNA release spliceosomal complex|,mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|double-stranded RNA binding|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,8,0.7,15.8,9,1.3,19.8,0.9,32.7,32.7,0.022,0,0,0.6,1.6
ENSMUSG00000025439,CLNS1A,"chloride channel, nucleotide-sensitive, 1A",nucleus|cytoplasm|cytosol|cytoskeleton|plasma membrane|methylosome|pICln-Sm protein complex|,spliceosomal snRNP assembly|chloride transport|cell volume homeostasis|,poly(A) RNA binding|,10,0.9,25.8,9,-1.3,9.86,0.9,32.5,32.5,0.0223,0,0,0.5,1.4
ENSMUSG00000021807,2700060E02RIK,RIKEN cDNA 2700060E02 gene,nucleus|cytoplasm|cytoskeleton|actin cytoskeleton|tRNA-splicing ligase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core binding|identical protein binding|poly(A) RNA binding|,10,-1,26.9,10,1.1,7.6,-1,32.5,-32.5,0.0223,0,0,-1.8,-0.6
ENSMUSG00000025137,PCYT2,"phosphate cytidylyltransferase 2, ethanolamine",None,lipid metabolic process|phospholipid biosynthetic process|biosynthetic process|,catalytic activity|ethanolamine-phosphate cytidylyltransferase activity|transferase activity|nucleotidyltransferase activity|,8,0.6,11,9,1.7,25.9,0.9,32.3,32.3,0.0227,0,0,0.4,2.3
ENSMUSG00000062328,RPL17,ribosomal protein L17,intracellular|nucleus|ribosome|large ribosomal subunit|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,2,1.4,31.6,3,0.6,1.29,1.4,31.5,31.5,0.0241,0,0,0.8,2
ENSMUSG00000024999,NOC3L,nucleolar complex associated 3 homolog (S. cerevisiae),nucleus|nucleolus|nuclear speck|,fat cell differentiation|,poly(A) RNA binding|,10,1.6,24.6,10,-1.3,12.6,1.5,30.7,30.7,0.0256,0,0,0.9,2.7
ENSMUSG00000029536,GATC,"glutamyl-tRNA(Gln) amidotransferase, subunit C",mitochondrion|mitochondrion|glutamyl-tRNA(Gln) amidotransferase complex|,translation|regulation of translational fidelity|mitochondrial translation|glutaminyl-tRNAGln biosynthesis via transamidation|,"nucleotide binding|ATP binding|ligase activity|cobyrinate a,c-diamide synthase activity|glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity|",10,-1,30.2,10,-0.4,1.97,-0.9,30.6,-30.6,0.0259,0,0,-1.5,-0.3
ENSMUSG00000032840,2410131K14RIK,RIKEN cDNA 2410131K14 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-1.1,24.3,10,-1.2,5.97,-1.1,29.8,-29.8,0.0277,0,0,-2,-0.8
ENSMUSG00000063787,CHCHD1,coiled-coil-helix-coiled-coil-helix domain containing 1,nucleus|nucleolus|cytoplasm|mitochondrion|mitochondrion|,biological_process|,poly(A) RNA binding|,10,-0.5,19.4,10,-1.1,14.5,-0.7,29.1,-29.1,0.0299,0,0,-1.3,-0.4
ENSMUSG00000026766,MMADHC,"methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria",cellular_component|cytoplasm|mitochondrion|,biological_process|cobalamin metabolic process|,molecular_function|,10,-0.9,28.5,10,-0.3,2.14,-0.9,27.9,-27.9,0.0344,0,0,-1.6,-0.4
ENSMUSG00000018171,VMP1,vacuole membrane protein 1,pre-autophagosomal structure|autophagic vacuole membrane|vacuole|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,autophagy|cell adhesion|embryo implantation|regulation of autophagy|regulation of autophagy|single organismal cell-cell adhesion|cell junction assembly|,molecular_function|,9,0.7,21.7,9,0.9,5.05,0.7,26.3,26.3,0.0427,0,0,0.5,1.1
ENSMUSG00000027357,CRLS1,cardiolipin synthase 1,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,lipid metabolic process|biological_process|phospholipid biosynthetic process|,"molecular_function|cardiolipin synthase activity|transferase activity|phosphotransferase activity, for other substituted phosphate groups|UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity|GDP-mannose:serine-protein mannose-1-phosphotransferase activity|archaetidylserine synthase activity|",10,0.7,16.2,10,0.7,10,0.7,25.8,25.8,0.046,0,0,0.4,1
ENSMUSG00000052798,NUP107,nucleoporin 107,"chromosome, centromeric region|kinetochore|nucleus|nuclear pore|chromosome|centrosome|membrane|membrane|nuclear pore outer ring|nuclear membrane|nuclear periphery|",mRNA export from nucleus|transport|protein transport|mRNA transport|nuclear pore complex assembly|,nucleocytoplasmic transporter activity|structural constituent of nuclear pore|,10,1,5.02,10,-1.8,28.1,-1.8,25,-25,0.0524,0,0,-3,-1.1
ENSMUSG00000007338,MRPL49,mitochondrial ribosomal protein L49,intracellular|mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,translation|biological_process|,molecular_function|structural constituent of ribosome|,9,0.9,22.1,9,0.7,3.65,0.9,24.9,24.9,0.0532,0,0,0.4,1.4
ENSMUSG00000021666,GFM2,"G elongation factor, mitochondrial 2",mitochondrion|mitochondrion|,GTP catabolic process|translation|mitochondrial translation|ribosome disassembly|,nucleotide binding|GTPase activity|GTP binding|,10,0.6,11.4,10,1.2,17.6,0.9,24.8,24.8,0.0538,0,0,0.6,1.5
ENSMUSG00000025940,TMEM70,transmembrane protein 70,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial membrane|,mitochondrial proton-transporting ATP synthase complex assembly|,molecular_function|,10,1.3,23.8,10,0.4,3.95,1.1,24.4,24.4,0.0576,0,0,0.3,1.8
ENSMUSG00000064267,HVCN1,hydrogen voltage-gated channel 1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|integral component of membrane|,transport|ion transport|response to pH|response to zinc ion|response to zinc ion|proton transport|proton transport|ion transmembrane transport|regulation of ion transmembrane transport|transmembrane transport|cellular response to zinc ion|cellular response to pH|,ion channel activity|voltage-gated ion channel activity|voltage-gated proton channel activity|voltage-gated proton channel activity|,10,0,0,10,1.8,27.5,1.8,24.3,24.3,0.0585,0,0,1,3
ENSMUSG00000028889,YRDC,yrdC domain containing (E.coli),mitochondrion|membrane|,negative regulation of transport|,double-stranded RNA binding|protein binding|,9,-1.3,23.6,9,0.9,11,0.8,23.9,23.9,0.0626,0,0,-1.8,2
ENSMUSG00000028998,TOMM7,translocase of outer mitochondrial membrane 7 homolog (yeast),mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane translocase complex|membrane|integral component of membrane|,transport|biological_process|protein transport|protein import into mitochondrial matrix|,molecular_function|,9,0.8,19.9,9,0.5,5.8,0.6,23.5,23.5,0.0672,0,0,0.5,1.1
ENSMUSG00000059602,SYN3,synapsin III,synaptic vesicle|membrane|cell junction|synaptic vesicle membrane|cytoplasmic vesicle|synapse|,neurotransmitter secretion|,nucleotide binding|catalytic activity|ATP binding|,10,1.4,24.1,10,0.4,1.92,1.3,23.5,23.5,0.0672,0,0,0.6,2
ENSMUSG00000032563,MRPL3,mitochondrial ribosomal protein L3,intracellular|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,0.2,0.466,10,2,26.7,2,23.5,23.5,0.0672,0,0,0.8,4
ENSMUSG00000001305,RRP15,ribosomal RNA processing 15 homolog (S. cerevisiae),nucleus|nucleolus|mitochondrion|,biological_process|,molecular_function|,10,0.7,19.2,10,0.4,5.34,0.7,23.4,23.4,0.0683,0,0,0.4,1.2
ENSMUSG00000022337,EMC2,ER membrane protein complex subunit 2,nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|ER membrane protein complex|,biological_process|,molecular_function|,10,0.4,8.51,10,1.4,22.8,1.3,23.3,23.3,0.0695,0,0,0.7,1.9
ENSMUSG00000034211,MRPS17,mitochondrial ribosomal protein S17,intracellular|mitochondrion|ribosome|ribonucleoprotein complex|,translation|biological_process|,molecular_function|RNA binding|structural constituent of ribosome|rRNA binding|,10,0.3,7.35,10,-1.9,26.8,-1.9,23.1,-23.1,0.0718,0,0,-4,-1.3
ENSMUSG00000036678,AAAS,"achalasia, adrenocortical insufficiency, alacrimia",nucleus|nuclear pore|cytoplasm|centrosome|membrane|nuclear membrane|,transport|nucleocytoplasmic transport|learning|fertilization|protein transport|mRNA transport|,molecular_function|,9,0.5,10.5,9,0.9,16.1,0.7,22.9,22.9,0.0744,0,0,0.4,1.1
ENSMUSG00000070565,RASAL2,RAS protein activator like 2,cytoplasm|intrinsic component of the cytoplasmic side of the plasma membrane|,positive regulation of Ras GTPase activity|negative regulation of Ras protein signal transduction|,GTPase activator activity|Ras GTPase activator activity|,10,1.7,25,10,0.4,3.04,1.6,22.9,22.9,0.0744,0,0,1,3
ENSMUSG00000058558,RPL5,ribosomal protein L5,intracellular|nucleus|nucleolus|cytoplasm|ribosome|membrane|aminoacyl-tRNA synthetase multienzyme complex|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,rRNA processing|translation|positive regulation of phosphatase activity|ribosomal large subunit biogenesis|,RNA binding|structural constituent of ribosome|protein binding|5S rRNA binding|rRNA binding|poly(A) RNA binding|,6,-1.1,25.4,6,0.3,3.73,-1.1,22.8,-22.8,0.0757,0,0,-2,-0.7
ENSMUSG00000026623,LPGAT1,lysophosphatidylglycerol acyltransferase 1,cytoplasm|endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|biological_process|metabolic process|phospholipid biosynthetic process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.2,2.84,10,1.7,23.1,0.4,22.6,22.6,0.0785,0,0,0.3,2.7
ENSMUSG00000048439,NUPL2,nucleoporin like 2,nucleus|nuclear pore|membrane|,transport|protein transport|mRNA transport|,poly(A) RNA binding|metal ion binding|,9,-1.1,25.6,9,0.6,1.41,-1.1,22.6,-22.6,0.0785,0,0,-2,-0.6
ENSMUSG00000061979,WBSCR16,Williams-Beuren syndrome chromosome region 16 homolog (human),mitochondrion|,positive regulation of Ran GTPase activity|,Ran guanyl-nucleotide exchange factor activity|poly(A) RNA binding|,5,0.5,4.97,5,1.2,19.7,1.1,22.2,22.2,0.0846,0,0,0.6,1.8
ENSMUSG00000002308,CD320,CD320 antigen,endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,regulation of vitamin metabolic process|,growth factor activity|cobalamin binding|,10,0.4,9.67,10,2.7,23.8,2.6,22.1,22.1,0.086,0,0,1.4,5
ENSMUSG00000034729,MRPS10,mitochondrial ribosomal protein S10,mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|biological_process|,structural constituent of ribosome|,10,1.5,24.2,10,0.3,2.32,1.5,21.9,21.9,0.0892,0,0,0.8,3
ENSMUSG00000036983,TFB1M,"transcription factor B1, mitochondrial",mitochondrion|mitochondrial nucleoid|,"rRNA modification|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|DNA binding|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,1.2,24.4,9,0.2,0.125,1.2,21.9,21.9,0.0892,0,0,0.3,2
ENSMUSG00000060636,RPL35A,ribosomal protein L35A,intracellular|mitochondrion|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,rRNA processing|translation|ribosomal large subunit biogenesis|,structural constituent of ribosome|poly(A) RNA binding|,6,0.5,5.55,6,-1.6,24.7,-1.6,21.8,-21.8,0.0908,0,0,-3,-1.1
ENSMUSG00000032018,SC5D,"sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|fatty acid biosynthetic process|steroid biosynthetic process|steroid metabolic process|sterol biosynthetic process|cholesterol biosynthetic process via lathosterol|oxidation-reduction process|,C-5 sterol desaturase activity|iron ion binding|oxidoreductase activity|lathosterol oxidase activity|,10,-1,25,10,0,0,-1,21.8,-21.8,0.0908,0,0,-2,-0.7
ENSMUSG00000044792,ISCA1,iron-sulfur cluster assembly 1 homolog (S. cerevisiae),mitochondrion|,biological_process|iron-sulfur cluster assembly|,molecular_function|structural molecule activity|metal ion binding|iron-sulfur cluster binding|,7,0.9,13.1,7,1.1,9.02,0.9,21.6,21.6,0.0938,0,0,0.6,1.6
ENSMUSG00000005299,LETM1,leucine zipper-EF-hand containing transmembrane protein 1,mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|membrane|integral component of membrane|,cristae formation|,metal ion binding|,10,0.3,0.731,10,-2.1,25,-2.1,21.4,-21.4,0.0975,0,0,-4,-1.6
ENSMUSG00000006519,CYBA,"cytochrome b-245, alpha polypeptide",cytoplasm|mitochondrion|endosome|Golgi apparatus|plasma membrane|membrane|membrane|apical plasma membrane|dendrite|NADPH oxidase complex|NADPH oxidase complex|neuronal cell body|perinuclear endoplasmic reticulum|,positive regulation of endothelial cell proliferation|negative regulation of glomerular filtration by angiotensin|superoxide metabolic process|transport|inflammatory response|regulation of blood pressure|smooth muscle hypertrophy|cytochrome complex assembly|positive regulation of cell growth|superoxide anion generation|innate immune response|respiratory burst|positive regulation of smooth muscle cell proliferation|hydrogen peroxide biosynthetic process|regulation of release of sequestered calcium ion into cytosol|oxidation-reduction process|positive regulation of mucus secretion|cellular response to organic substance|reactive oxygen species metabolic process|,protein binding|electron carrier activity|superoxide-generating NADPH oxidase activity|oxidoreductase activity|SH3 domain binding|heme binding|metal ion binding|protein heterodimerization activity|,10,1.4,24.2,10,0.1,0.358,1.3,21.2,21.2,0.101,0,0,0.6,2
ENSMUSG00000013736,TRNT1,"tRNA nucleotidyl transferase, CCA-adding, 1",intracellular|mitochondrion|mitochondrion|mitochondrion|,tRNA 3'-terminal CCA addition|RNA processing|tRNA processing|tRNA 3'-end processing|,tRNA binding|nucleotide binding|RNA binding|tRNA adenylyltransferase activity|ATP binding|tRNA nucleotidyltransferase activity|transferase activity|nucleotidyltransferase activity|CTP:tRNA cytidylyltransferase activity|CTP:3'-cytidine-tRNA cytidylyltransferase activity|ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity|,9,-1.2,24.1,8,0.9,13.5,-1.2,21.2,-21.2,0.101,0,0,-2,-0.6
ENSMUSG00000021660,BTF3,basic transcription factor 3,nucleus|cytoplasm|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|transport|protein transport|",poly(A) RNA binding|,10,-1.5,24.5,10,0.1,0.15,-1.5,21.2,-21.2,0.101,0,0,-3,-1.2
ENSMUSG00000021040,SLIRP,SRA stem-loop interacting RNA binding protein,acrosomal vesicle|nucleus|cytoplasm|mitochondrion|mitochondrion|ribonucleoprotein complex|sperm flagellum|perinuclear region of cytoplasm|sperm part|,"negative regulation of mitochondrial RNA catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|spermatid development|single fertilization|sperm motility|mitochondrion morphogenesis|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-1,19.1,10,-1.1,2.32,-1,21.1,-21.1,0.103,0,0,-2,-0.6
ENSMUSG00000021692,DIMT1,DIM1 dimethyladenosine transferase 1-like (S. cerevisiae),nucleus|nucleolus|cytoplasm|,rRNA modification|rRNA processing|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|methyltransferase activity|rRNA methyltransferase activity|rRNA (adenine) methyltransferase activity|transferase activity|poly(A) RNA binding|18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity|",10,-1.2,24.4,10,1.2,14.8,-1.2,21,-21,0.105,0,0,-2,-0.7
ENSMUSG00000040913,FBXW4,F-box and WD-40 domain protein 4,None,positive regulation of mesenchymal cell proliferation|multicellular organismal development|Wnt signaling pathway|embryonic digit morphogenesis|cartilage development|limb development|limb development|,None,10,1.4,23.6,10,0.1,0.629,1.3,21,21,0.105,0,0,0.6,2
ENSMUSG00000025962,FASTKD2,FAST kinase domains 2,mitochondrion|mitochondrion|,cellular respiration|,protein kinase activity|poly(A) RNA binding|,10,-1.2,24.1,10,1.2,0.768,-1.2,21,-21,0.105,0,0,-2,-0.7
ENSMUSG00000020175,RAB36,"RAB36, member RAS oncogene family",cellular_component|Golgi apparatus|membrane|,transport|small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTP binding|,10,1.4,23.8,10,-0.1,0.317,1.4,20.8,20.8,0.11,0,0,0.7,2
ENSMUSG00000022701,2610015P09RIK,RIKEN cDNA 2610015P09 gene,cellular_component|,biological_process|,molecular_function|,10,-1.2,23.8,10,0.2,0.763,-1.1,20.5,-20.5,0.116,0,0,-2,-0.7
ENSMUSG00000024055,CYP4F13,"cytochrome P450, family 4, subfamily f, polypeptide 13",cellular_component|,leukotriene metabolic process|oxidation-reduction process|,monooxygenase activity|oxidoreductase activity|metal ion binding|,10,0.2,1.92,10,1.9,23.4,1.9,20.3,20.3,0.121,0,0,0.6,3
ENSMUSG00000022142,NUP155,nucleoporin 155,intracellular|cell|nucleus|nuclear envelope|nuclear pore|cytoplasm|membrane|membrane|,mRNA export from nucleus|protein import into nucleus|transport|nucleocytoplasmic transport|nuclear envelope organization|protein transport|mRNA transport|atrial cardiac muscle cell action potential|,structural constituent of nuclear pore|,9,0.5,12.6,9,1,8.76,0.7,20.3,20.3,0.121,0,0,0.4,1.2
ENSMUSG00000022439,PARVG,"parvin, gamma",cellular_component|cytoplasm|cytoskeleton|plasma membrane|membrane|cell junction|,cell adhesion|biological_process|actin cytoskeleton reorganization|,actin binding|,10,0,0,10,1.8,23.7,1.8,20.1,20.1,0.127,0,0,0.7,3
ENSMUSG00000036860,MRPL55,mitochondrial ribosomal protein L55,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,10,2.6,21.8,10,-0.6,2.23,2.6,20.1,20.1,0.127,0,0,2.3,5
ENSMUSG00000022865,CXADR,coxsackie virus and adenovirus receptor,acrosomal vesicle|extracellular region|extracellular space|nucleus|plasma membrane|cell-cell junction|cell-cell junction|adherens junction|tight junction|tight junction|intercalated disc|intercalated disc|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apicolateral plasma membrane|cell junction|filopodium|growth cone|neuromuscular junction|neuron projection|neuron projection|protein complex|cell body|membrane raft|,mitochondrion organization|cell adhesion|heterophilic cell-cell adhesion|heart development|epithelial structure maintenance|single organismal cell-cell adhesion|neutrophil chemotaxis|actin cytoskeleton reorganization|homotypic cell-cell adhesion|cell-cell junction organization|gamma-delta T cell activation|cardiac muscle fiber development|defense response to virus|negative regulation of cardiac muscle cell proliferation|positive regulation of epithelial cell proliferation involved in wound healing|transepithelial transport|AV node cell to bundle of His cell communication|,receptor binding|integrin binding|protein binding|beta-catenin binding|beta-catenin binding|PDZ domain binding|identical protein binding|cell adhesion molecule binding|connexin binding|,10,0,0,10,1.9,23.6,1.8,19.9,19.9,0.132,0,0,1,3
ENSMUSG00000002825,QTRT1,queuine tRNA-ribosyltransferase 1,nucleus|cytoplasm|mitochondrion|,tRNA modification|tRNA processing|queuosine biosynthetic process|,"protein binding|queuine tRNA-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-1.3,23.1,10,1.6,18.6,-1.3,19.8,-19.8,0.135,0,0,-2,1.8
ENSMUSG00000028647,MYCBP,c-myc binding protein,nucleus|cytoplasm|centrosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",transcription coactivator activity|,10,0.1,0.0405,10,-1.6,23.4,-1.6,19.8,-19.8,0.135,0,0,-3,-1
ENSMUSG00000039680,MRPS6,mitochondrial ribosomal protein S6,mitochondrion|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|rRNA binding|,9,1.2,20.7,9,0.6,0.893,1,19.7,19.7,0.137,0,0,0.4,1.9
ENSMUSG00000037098,RAB11FIP3,RAB11 family interacting protein 3 (class II),nucleus|cytoplasm|endosome|centrosome|microtubule organizing center|cytoskeleton|membrane|midbody|cleavage furrow|intracellular membrane-bounded organelle|intercellular bridge|recycling endosome|,cytokinesis|transport|cell cycle|endocytic recycling|cell division|,calcium ion binding|protein binding|Rab GTPase binding|ADP-ribosylation factor binding|protein homodimerization activity|metal ion binding|,9,0,0,10,-1.6,22.8,-1.6,19.3,-19.3,0.149,0,0,-3,-1
ENSMUSG00000051586,MICAL3,"microtubule associated monooxygenase, calponin and LIM domain containing 3",nucleus|cytoplasm|cytoskeleton|,exocytosis|cytoskeleton organization|metabolic process|actin filament depolymerization|oxidation-reduction process|,"actin binding|monooxygenase activity|zinc ion binding|3-(3-hydroxyphenyl)propionate hydroxylase activity|oxidoreductase activity|4-chlorobenzaldehyde oxidase activity|3,5-xylenol methylhydroxylase activity|phenylacetate hydroxylase activity|4-nitrophenol 4-monooxygenase activity|dimethyl sulfide monooxygenase activity|alpha-pinene monooxygenase [NADH] activity|phenanthrene 9,10-monooxygenase activity|1-hydroxy-2-naphthoate hydroxylase activity|toluene 4-monooxygenase activity|xylene monooxygenase activity|dibenzothiophene monooxygenase activity|6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|chlorophenol 4-monooxygenase activity|carbon disulfide oxygenase activity|toluene 2-monooxygenase activity|1-hydroxy-2-oxolimonene 1,2-monooxygenase activity|phenanthrene 1,2-monooxygenase activity|tetrahydrofuran hydroxylase activity|styrene monooxygenase activity|toluene-4-sulfonate monooxygenase activity|toluene-sulfonate methyl-monooxygenase activity|3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|2-hydroxy-phenylacetate hydroxylase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity|phenanthrene 3,4-monooxygenase activity|toluene 3-monooxygenase activity|4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity|limonene monooxygenase activity|2-methylnaphthalene hydroxylase activity|1-methylnaphthalene hydroxylase activity|bisphenol A hydroxylase A activity|salicylate 5-hydroxylase activity|isobutylamine N-hydroxylase activity|branched-chain dodecylbenzene sulfonate monooxygenase activity|3-HSA hydroxylase activity|4-hydroxypyridine-3-hydroxylase activity|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity|6-hydroxynicotinate 3-monooxygenase activity|metal ion binding|tocotrienol omega-hydroxylase activity|thalianol hydroxylase activity|",10,0.6,4,10,-1.7,22.7,-1.6,19,-19,0.158,0,0,-3,-1.1
ENSMUSG00000038102,TRAPPC11,trafficking protein particle complex 11,cellular_component|Golgi apparatus|,transport|biological_process|vesicle-mediated transport|,molecular_function|,10,0.5,2.11,10,-1.8,22.5,-1.8,18.9,-18.9,0.161,0,0,-3,-1.2
ENSMUSG00000000959,OXA1L,oxidase assembly 1-like,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial membrane|integral component of mitochondrial membrane|protein complex|,aerobic respiration|negative regulation of ATPase activity|mitochondrial respiratory chain complex I assembly|mitochondrial proton-transporting ATP synthase complex assembly|protein insertion into membrane|protein tetramerization|negative regulation of oxidoreductase activity|mitochondrial respiratory chain complex I biogenesis|,protein homodimerization activity|mitochondrial ribosome binding|,10,-1,21.6,10,0.1,0.0536,-1,18.8,-18.8,0.163,0,0,-2,-0.4
ENSMUSG00000026516,NVL,nuclear VCP-like,nucleus|membrane|,biological_process|,nucleotide binding|ATP binding|poly(A) RNA binding|,8,0.5,6.59,8,1.4,14.8,0.9,18.7,18.7,0.165,0,0,0.5,1.9
ENSMUSG00000027374,MRPS5,mitochondrial ribosomal protein S5,mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,translation|,RNA binding|structural constituent of ribosome|poly(A) RNA binding|,10,-1,20.9,10,0.1,0.515,-1,18.1,-18.1,0.175,0,0,-2,-0.4
ENSMUSG00000000579,DYNLT1C,dynein light chain Tctex-type 1C,cellular_component|,biological_process|,identical protein binding|,4,0.5,12.1,4,0.7,7.23,0.6,18.1,18.1,0.175,0,0,0.3,1.3
ENSMUSG00000045160,BOLA3,bolA-like 3 (E. coli),cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.6,6.55,10,2.5,21.8,2.5,18.1,18.1,0.175,0,0,2.1,5
ENSMUSG00000057363,UXS1,UDP-glucuronate decarboxylase 1,mitochondrion|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,protein tetramerization|,catalytic activity|lyase activity|carboxy-lyase activity|protein homodimerization activity|UDP-glucuronate decarboxylase activity|coenzyme binding|NAD+ binding|,10,0.5,13.7,10,0.7,4.4,0.5,17.4,17.4,0.185,0,0,0.3,0.9
ENSMUSG00000023020,COX14,cytochrome c oxidase assembly protein 14,mitochondrion|mitochondrion|membrane|integral component of membrane|,mitochondrial respiratory chain complex IV assembly|,molecular_function|,10,-0.6,15.4,10,-0.3,2.9,-0.6,17.2,-17.2,0.187,0,0,-0.9,-0.3
ENSMUSG00000057229,ATP5SL,ATP5S-like,mitochondrion|,biological_process|,molecular_function|,10,0.8,9.28,10,0.6,8.11,0.8,16.4,16.4,0.195,0,0,0.3,1.3
ENSMUSG00000044533,RPS2,ribosomal protein S2,nucleus|nucleoplasm|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,ribosomal small subunit assembly|formation of translation preinitiation complex|positive regulation of transferase activity|cellular response to interleukin-4|,mRNA binding|structural constituent of ribosome|fibroblast growth factor binding|enzyme binding|protein complex binding|poly(A) RNA binding|,9,0.3,11.5,9,0.4,5.2,0.4,16.1,16.1,0.197,0,0,0.2,0.6
ENSMUSG00000027668,MFN1,mitofusin 1,mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,GTP catabolic process|multicellular organismal development|mitochondrial fusion|mitochondrial fusion|,nucleotide binding|GTPase activity|protein binding|GTP binding|hydrolase activity|,10,-0.6,16.2,10,-0.3,1.33,-0.6,16,-16,0.198,0,0,-1,-0.3
ENSMUSG00000013701,TIMM23,translocase of inner mitochondrial membrane 23,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial inner membrane presequence translocase complex|mitochondrial intermembrane space|integral component of mitochondrial inner membrane|,None,enzyme binding|,5,-0.8,18,5,1.4,9.72,-0.8,15.9,-15.9,0.198,0,0,-2,1.3
ENSMUSG00000044252,OSBPL1A,oxysterol binding protein-like 1A,nucleus|cytoplasm|endosome|late endosome|extracellular vesicular exosome|,transport|lipid transport|biological_process|,protein binding|lipid binding|cholesterol binding|,10,-0.4,16.1,10,0,0,-0.4,15.4,-15.4,0.201,0,0,-0.8,-0.2
ENSMUSG00000042737,DPM3,dolichyl-phosphate mannosyltransferase polypeptide 3,endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|dolichol-phosphate-mannose synthase complex|,GPI anchor biosynthetic process|regulation of protein stability|,dolichyl-phosphate beta-D-mannosyltransferase activity|,10,0.5,11.8,10,0.4,3.84,0.5,15.3,15.3,0.202,0,0,0.2,0.8
ENSMUSG00000022370,MRPL13,mitochondrial ribosomal protein L13,mitochondrion|mitochondrial ribosome|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,0.7,14.1,10,0.4,2.25,0.6,15.1,15.1,0.203,0,0,0.3,1.1
ENSMUSG00000035704,ALG8,"asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)",cellular_component|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,protein N-linked glycosylation|mannosylation|,"alpha-1,3-mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,0.5,10.6,10,0.6,4.98,0.5,15.1,15.1,0.203,0,0,0.3,0.9
ENSMUSG00000044881,COA4,cytochrome c oxidase assembly factor 4,cellular_component|mitochondrion|,biological_process|,molecular_function|,10,0.6,11.3,10,1.3,7.12,0.9,15,15,0.204,0,0,0.5,1.7
ENSMUSG00000028653,TRIT1,tRNA isopentenyltransferase 1,nucleus|cytoplasm|mitochondrion|,tRNA processing|,nucleotide binding|ATP binding|transferase activity|metal ion binding|tRNA dimethylallyltransferase activity|,10,0.8,14.2,10,0.4,2.12,0.5,14.7,14.7,0.205,0,0,0.3,1.3
ENSMUSG00000021650,PTCD2,pentatricopeptide repeat domain 2,mitochondrion|mitochondrion|,kidney development|liver development|mRNA processing|mitochondrion organization|heart development|regulation of gene expression|muscle fiber development|regulation of mRNA processing|ventricular cardiac muscle tissue morphogenesis|,poly(A) RNA binding|,10,-0.4,12.4,10,-0.3,2.85,-0.4,14.6,-14.6,0.206,0,0,-0.6,-0.2
ENSMUSG00000020180,SNRPD3,small nuclear ribonucleoprotein D3,nucleus|nucleus|spliceosomal complex|U7 snRNP|U1 snRNP|U4 snRNP|U12-type spliceosomal complex|cytoplasm|cytoplasm|cytosol|virion|viral nucleocapsid|ribonucleoprotein complex|methylosome|pICln-Sm protein complex|SMN-Sm protein complex|extracellular vesicular exosome|catalytic step 2 spliceosome|,spliceosomal snRNP assembly|mRNA processing|RNA splicing|,RNA binding|enzyme binding|poly(A) RNA binding|histone pre-mRNA DCP binding|,6,0.7,10.2,5,0.7,4.61,0.7,14.5,14.5,0.206,0,0,0.4,1.5
ENSMUSG00000020290,XPO1,"exportin 1, CRM1 homolog (yeast)",kinetochore|intracellular|cell|nucleus|nucleus|annulate lamellae|cytoplasm|membrane|ribonucleoprotein complex|nuclear membrane|intracellular membrane-bounded organelle|,ribosomal large subunit export from nucleus|ribosomal small subunit export from nucleus|negative regulation of transcription from RNA polymerase II promoter|protein export from nucleus|protein export from nucleus|protein export from nucleus|transport|intracellular protein transport|regulation of centrosome duplication|protein transport|protein localization to nucleus|regulation of protein catabolic process|regulation of protein export from nucleus|mRNA transport|,RNA binding|nucleocytoplasmic transporter activity|protein binding|Ran GTPase binding|protein transporter activity|protein domain specific binding|,8,0.5,6.12,10,1.4,9.74,0.6,14,14,0.209,0,0,0.2,1.7
ENSMUSG00000016257,SLMO2,slowmo homolog 2 (Drosophila),mitochondrion|mitochondrial intermembrane space|,phospholipid transport|,phosphatidic acid transporter activity|,8,0.6,3.7,8,-0.8,12.9,-0.7,13.9,-13.9,0.21,0,0,-1.5,-0.4
ENSMUSG00000016510,MTIF3,mitochondrial translational initiation factor 3,mitochondrion|,formation of translation initiation complex|translation|translational initiation|regulation of translational initiation|regulation of translational initiation|ribosome disassembly|ribosome disassembly|,"translation initiation factor activity|translation factor activity, nucleic acid binding|translation factor activity, nucleic acid binding|ribosomal small subunit binding|ribosomal small subunit binding|",10,-0.4,11.7,10,-0.3,2.58,-0.4,13.8,-13.8,0.21,0,0,-0.8,-0.2
ENSMUSG00000030868,DCTN5,dynactin 5,"chromosome, centromeric region|kinetochore|chromosome|cytoplasm|centrosome|cytoskeleton|dynactin complex|",biological_process|,molecular_function|,7,0.7,14.7,7,0.3,0.124,0.7,13.6,13.6,0.211,0,0,0.4,1.5
ENSMUSG00000035161,INTS6,integrator complex subunit 6,nucleus|actin cytoskeleton|integrator complex|,snRNA processing|,None,10,-0.5,13.4,10,-0.2,1.11,-0.4,13.6,-13.6,0.211,0,0,-0.8,-0.2
ENSMUSG00000056870,GULP1,"GULP, engulfment adaptor PTB domain containing 1",cytoplasm|,"transport|lipid transport|phagocytosis|phagocytosis, engulfment|apoptotic process|",molecular_function|,10,-0.6,16,10,0.1,0.212,-0.5,13.6,-13.6,0.211,0,0,-1.2,-0.3
ENSMUSG00000050323,NDUFAF6,"NADH dehydrogenase (ubiquinone) complex I, assembly factor 6",nucleus|cytoplasm|mitochondrion|mitochondrial inner membrane|membrane|,biosynthetic process|mitochondrial respiratory chain complex I assembly|,molecular_function|transferase activity|,10,0.5,12.6,10,0.5,0.907,0.5,13.2,13.2,0.214,0,0,0.3,0.9
ENSMUSG00000028868,WASF2,"WAS protein family, member 2",ruffle|intracellular|intracellular|cytoplasm|early endosome|cytoskeleton|cell-cell junction|lamellipodium|lamellipodium|SCAR complex|extracellular vesicular exosome|,angiogenesis|ameboidal cell migration|endocytosis|cellular component movement|positive regulation of lamellipodium assembly|Rac protein signal transduction|lamellipodium assembly|actin cytoskeleton organization|actin filament-based movement|megakaryocyte development|negative regulation of stress fiber assembly|lamellipodium morphogenesis|,actin binding|protein binding|protein complex binding|,10,1,5.73,10,-0.8,11.2,-0.8,13.1,-13.1,0.214,0,0,-2,-0.4
ENSMUSG00000029815,MALSU1,mitochondrial assembly of ribosomal large subunit 1,mitochondrion|,ribosomal large subunit biogenesis|negative regulation of mitochondrial translation|,molecular_function|,10,0.8,10.1,10,0.9,3.49,0.8,13.1,13.1,0.214,0,0,0.3,1.4
ENSMUSG00000063362,ALG11,"asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,biosynthetic process|,"molecular_function|GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",9,-0.4,12.5,9,0.7,4.22,-0.4,13,-13,0.215,0,0,-0.8,-0.2
ENSMUSG00000026087,MRPL30,mitochondrial ribosomal protein L30,mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,9,1.2,15.3,9,-0.4,0.747,1.1,13,13,0.215,0,0,0.5,2
ENSMUSG00000030004,NAT8,"N-acetyltransferase 8 (GCN5-related, putative)",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,gastrulation with mouth forming second|gastrulation with mouth forming second|negative regulation of cell adhesion|multicellular organismal development|gastrulation|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,1.2,15,10,0.2,0.745,1.1,12.9,12.9,0.216,0,0,0.4,2
ENSMUSG00000031059,NDUFB11,"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,-0.5,4.5,10,-0.7,9.08,-0.6,12.7,-12.7,0.217,0,0,-1.3,-0.3
ENSMUSG00000003437,PAF1,"Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)",nucleus|Cdc73/Paf1 complex|,"negative regulation of transcription from RNA polymerase II promoter|endodermal cell fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA polyadenylation|histone monoubiquitination|Wnt signaling pathway|stem cell maintenance|positive regulation of mRNA 3'-end processing|positive regulation of transcription elongation from RNA polymerase II promoter|histone H2B ubiquitination|negative regulation of myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|cellular response to lipopolysaccharide|",RNA polymerase II core binding|chromatin binding|protein binding|,6,0.6,13.3,7,0.2,0.683,0.5,12.6,12.6,0.218,0,0,0.3,1.3
ENSMUSG00000056698,ELMOD3,ELMO/CED-12 domain containing 3,cellular_component|cytoplasm|cytoskeleton|cilium|cell projection|,phagocytosis|biological_process|,molecular_function|GTPase activator activity|,10,0.8,10.9,10,0.5,2.22,0.8,12.5,12.5,0.218,0,0,0.3,1.4
ENSMUSG00000032480,DHX30,DEAH (Asp-Glu-Ala-His) box polypeptide 30,cytoplasm|mitochondrion|mitochondrial nucleoid|,biological_process|,nucleotide binding|nucleic acid binding|chromatin binding|RNA binding|double-stranded RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,1,14.5,10,0.3,1.36,0.9,12.5,12.5,0.218,0,0,0.3,1.9
ENSMUSG00000042496,PRDM10,PR domain containing 10,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|DNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.7,7.09,10,0.8,5.93,0.7,12.5,12.5,0.218,0,0,0.4,1.5
ENSMUSG00000023156,RPP14,ribonuclease P 14 subunit,cellular_component|nucleus|,tRNA processing|biological_process|,ribonuclease P activity|ribonuclease activity|hydrolase activity|,9,0.5,4.73,9,0.7,8.46,0.6,12.4,12.4,0.219,0,0,0.3,1
ENSMUSG00000049106,DCAF5,DDB1 and CUL4 associated factor 5,mitochondrion|Cul4-RING E3 ubiquitin ligase complex|,biological_process|,molecular_function|,10,0.5,8.5,10,0.4,4.25,0.4,12.3,12.3,0.22,0,0,0.2,0.7
ENSMUSG00000026097,ORMDL1,ORM1-like 1 (S. cerevisiae),endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,ceramide metabolic process|,molecular_function|,10,-0.2,4.04,10,-0.9,12.1,-0.6,12.2,-12.2,0.22,0,0,-1.3,-0.2
ENSMUSG00000006333,RPS9,ribosomal protein S9,intracellular|nucleus|nucleolus|cytoplasm|ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|regulation of translation|positive regulation of cell proliferation|,RNA binding|structural constituent of ribosome|rRNA binding|poly(A) RNA binding|translation regulator activity|,7,0.6,4.52,7,0.9,9.28,0.7,12.1,12.1,0.221,0,0,0.3,1.5
ENSMUSG00000025817,NUDT5,nudix (nucleoside diphosphate linked moiety X)-type motif 5,nucleus|extracellular vesicular exosome|,nucleobase-containing compound metabolic process|ribonucleoside diphosphate catabolic process|,magnesium ion binding|RNA binding|hydrolase activity|nucleoside-diphosphatase activity|ADP-sugar diphosphatase activity|snoRNA binding|metal ion binding|ADP-ribose diphosphatase activity|,10,0.4,11.2,10,0.7,1.88,0.4,12.1,12.1,0.221,0,0,0.2,0.8
ENSMUSG00000028261,NDUFAF4,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4",mitochondrion|mitochondrion|mitochondrial membrane|,positive regulation of cell proliferation|NADH dehydrogenase complex assembly|mitochondrial respiratory chain complex I assembly|negative regulation of apoptotic process|,molecular_function|calmodulin binding|,10,-1,15.1,10,0.3,0.883,-0.9,12,-12,0.222,0,0,-2,-0.3
ENSMUSG00000001440,KPNB1,karyopherin (importin) beta 1,intracellular|cell|nucleus|nuclear envelope|cytoplasm|membrane|nuclear membrane|protein complex|extracellular vesicular exosome|endoplasmic reticulum tubular network|,protein import into nucleus|protein import into nucleus|ribosomal protein import into nucleus|ribosomal protein import into nucleus|transport|intracellular protein transport|nucleocytoplasmic transport|protein transport|,protein binding|Ran GTPase binding|protein transporter activity|enzyme binding|protein domain specific binding|poly(A) RNA binding|,3,0.6,3.21,4,1,9.82,1,11.9,11.9,0.223,0,0,0.5,1.9
ENSMUSG00000030706,MRPL48,mitochondrial ribosomal protein L48,mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,10,0.4,3.04,10,-1.4,13.8,-1.3,11.1,-11.1,0.23,0,0,-2,0.5
ENSMUSG00000030766,ARHGAP17,Rho GTPase activating protein 17,intracellular|cytoplasm|plasma membrane|tight junction|membrane|cell junction|,actin filament organization|signal transduction|calcium ion-dependent exocytosis|,molecular_function|GTPase activator activity|SH3 domain binding|,10,0.3,5.65,10,0.4,6.29,0.4,11.1,11.1,0.23,0,0,0.2,0.7
ENSMUSG00000027519,RAB22A,"RAB22A, member RAS oncogene family",endosome|early endosome|plasma membrane|actin cytoskeleton|membrane|cytoplasmic vesicle|cell projection|phagocytic vesicle|extracellular vesicular exosome|,GTP catabolic process|transport|endocytosis|small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|,10,0.3,4.01,10,0.7,9.62,0.5,11,11,0.231,0,0,0.2,1.3
ENSMUSG00000019710,MRPL24,mitochondrial ribosomal protein L24,intracellular|mitochondrion|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,10,0.4,10.1,10,0.3,0.926,0.3,10.7,10.7,0.233,0,0,0.2,0.9
ENSMUSG00000067288,RPS28,ribosomal protein S28,intracellular|cytoplasm|ribosome|small ribosomal subunit|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,rRNA processing|rRNA export from nucleus|translation|ribosomal small subunit biogenesis|,structural constituent of ribosome|poly(A) RNA binding|,2,0.2,0.174,2,-1,12.1,-1,10.7,-10.7,0.233,0,0,-2,-0.6
ENSMUSG00000024816,FRMD8,FERM domain containing 8,cellular_component|cytoskeleton|,biological_process|,molecular_function|,10,1.1,9.9,10,0.5,4.33,0.5,10.6,10.6,0.234,0,0,0.2,1.9
ENSMUSG00000034595,PPP1R18,"protein phosphatase 1, regulatory subunit 18",cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|actin binding|phosphatase binding|,10,0.5,5.14,10,0.4,5.72,0.5,10.4,10.4,0.236,0,0,0.2,1.2
ENSMUSG00000015672,MRPL32,mitochondrial ribosomal protein L32,mitochondrion|mitochondrial large ribosomal subunit|ribosome|large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,-0.8,13.5,10,1.2,11.3,-0.8,10.4,-10.4,0.236,0,0,-2,1.4
ENSMUSG00000031527,ERI1,exoribonuclease 1,nucleus|nucleolus|nucleolus|cytoplasm|cytoplasm|histone pre-mRNA 3'end processing complex|,rRNA processing|gene silencing by RNA|rRNA 3'-end processing|nucleic acid phosphodiester bond hydrolysis|,nucleic acid binding|RNA binding|nuclease activity|exonuclease activity|3'-5' exonuclease activity|hydrolase activity|rRNA binding|phosphoric ester hydrolase activity|ribosome binding|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|histone pre-mRNA stem-loop binding|,10,-0.6,3.37,10,-0.6,7.33,-0.6,10.3,-10.3,0.237,0,0,-1.2,-0.2
ENSMUSG00000020823,SEC14L1,SEC14-like 1 (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0.5,9.83,10,0.3,1.98,0.4,10.2,10.2,0.238,0,0,0.2,0.9
ENSMUSG00000047649,CD3EAP,"CD3E antigen, epsilon polypeptide associated protein",nucleus|nucleolus|nucleolus|DNA-directed RNA polymerase I complex|cytoplasm|mitochondrion|,rRNA transcription|,protein binding|poly(A) RNA binding|,9,-0.6,12,9,0.4,1.49,-0.6,10.2,-10.2,0.238,0,0,-1.6,-0.3
ENSMUSG00000004788,EIF2B2,"eukaryotic translation initiation factor 2B, subunit 2 beta",cytoplasm|cytoplasm|eukaryotic translation initiation factor 2B complex|eukaryotic translation initiation factor 2B complex|,ovarian follicle development|translation|translational initiation|regulation of translational initiation|central nervous system development|response to heat|response to glucose|oligodendrocyte development|myelination|response to peptide hormone|positive regulation of GTPase activity|positive regulation of GTPase activity|cellular metabolic process|cellular response to stimulus|,translation initiation factor activity|guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|ATP binding|GTP binding|,7,0.5,9.01,5,-0.8,6.93,0.5,10.2,10.2,0.238,0,0,-0.9,2
ENSMUSG00000018446,C1QBP,"complement component 1, q subcomponent binding protein",extracellular region|extracellular space|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial matrix|cytosol|plasma membrane|cell surface|membrane|,"negative regulation of transcription from RNA polymerase II promoter|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|apoptotic process|complement activation, classical pathway|RNA splicing|phosphatidylinositol 3-kinase signaling|regulation of complement activation|negative regulation of interferon-gamma production|negative regulation of interleukin-12 production|negative regulation of MDA-5 signaling pathway|negative regulation of RIG-I signaling pathway|ribosome biogenesis|mature ribosome assembly|mature ribosome assembly|positive regulation of apoptotic process|innate immune response|positive regulation of cell adhesion|negative regulation of mRNA splicing, via spliceosome|negative regulation of defense response to virus|positive regulation of protein kinase B signaling|positive regulation of mitochondrial translation|positive regulation of neutrophil chemotaxis|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of trophoblast cell migration|positive regulation of dendritic cell chemotaxis|",complement component C1q binding|transcription corepressor activity|mRNA binding|protein kinase C binding|protein binding|hyaluronic acid binding|transcription factor binding|kininogen binding|adrenergic receptor binding|mitochondrial ribosome binding|,10,-0.3,3.75,10,-0.7,9.05,-0.5,10.1,-10.1,0.239,0,0,-1.2,-0.2
ENSMUSG00000021357,EXOC2,exocyst complex component 2,exocyst|exocyst|membrane|intracellular membrane-bounded organelle|,transport|exocytosis|Golgi to plasma membrane transport|protein transport|positive regulation of exocytosis|,Ral GTPase binding|protein N-terminus binding|,9,0.3,2.52,9,0.8,10.9,0.7,9.97,9.97,0.24,0,0,0.1,1.3
ENSMUSG00000027099,MTX2,metaxin 2,mitochondrion|mitochondrial outer membrane|membrane|,protein targeting to mitochondrion|transport|biological_process|protein transport|,molecular_function|,10,0.4,5.23,10,0.7,5.78,0.5,9.94,9.94,0.241,0,0,0.2,1.1
ENSMUSG00000058440,NRF1,nuclear respiratory factor 1,nucleus|transcription factor complex|cytoplasm|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|mitochondrion organization|positive regulation of transcription from RNA polymerase II promoter|response to electrical stimulus|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.7,8.1,10,-1.2,3.47,-0.8,9.81,-9.81,0.242,0,0,-1.9,-0.5
ENSMUSG00000024234,MTPAP,mitochondrial poly(A) polymerase,nucleus|cytoplasm|mitochondrion|mitochondrion|Golgi apparatus|plasma membrane|,"transcription, DNA-templated|mRNA polyadenylation|mRNA processing|histone mRNA catabolic process|",nucleotide binding|magnesium ion binding|UTP binding|RNA binding|polynucleotide adenylyltransferase activity|ATP binding|transferase activity|manganese ion binding|identical protein binding|protein homodimerization activity|poly(A) RNA binding|metal ion binding|,10,-0.9,8.98,10,-0.5,1.44,-0.8,9.61,-9.61,0.245,0,0,-1.8,-0.2
ENSMUSG00000046722,CDC42SE1,CDC42 small effector 1,cytoplasm|cytoskeleton|plasma membrane|cell cortex|membrane|,phagocytosis|small GTPase mediated signal transduction|regulation of cell shape|negative regulation of JNK cascade|,molecular_function|,10,0.5,10.3,10,0.1,0.399,0.5,9.61,9.61,0.245,0,0,0.2,1
ENSMUSG00000022350,E430025E21RIK,RIKEN cDNA E430025E21 gene,cytoplasm|endosome|endosome|endoplasmic reticulum|WASH complex|,endosomal transport|,molecular_function|,10,0.4,5.07,10,0.6,5.16,0.5,9.52,9.52,0.245,0,0,0.2,1
ENSMUSG00000000743,CHMP1A,charged multivesicular body protein 1A,condensed nuclear chromosome|nucleus|cytoplasm|endosome|early endosome|microtubule organizing center|endomembrane system|membrane|nuclear matrix|extracellular vesicular exosome|,"cytokinesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transport|cell cycle|mitotic chromosome condensation|protein transport|vesicle-mediated transport|gene silencing|negative regulation of transcription by glucose|negative regulation of transcription, DNA-templated|cell division|",protein binding|protein domain specific binding|protein homodimerization activity|,10,0.3,5.35,10,0.6,5.4,0.4,9.5,9.5,0.246,0,0,0.1,0.8
ENSMUSG00000029780,NT5C3,"5'-nucleotidase, cytosolic III",cytoplasm|mitochondrion|endoplasmic reticulum|,metabolic process|nucleotide metabolic process|dephosphorylation|dephosphorylation|adenosine metabolic process|,nucleotide binding|magnesium ion binding|5'-nucleotidase activity|5'-nucleotidase activity|transferase activity|hydrolase activity|phosphatase activity|metal ion binding|,10,-0.5,1.86,10,-0.7,8.29,-0.6,9.41,-9.41,0.247,0,0,-1.3,-0.2
ENSMUSG00000037710,CISD1,CDGSH iron sulfur domain 1,mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,regulation of cellular respiration|,"iron ion binding|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,-0.3,1.83,10,-1.3,10.5,-1.1,9.24,-9.24,0.249,0,0,-1.9,-0.2
ENSMUSG00000010097,NXF1,nuclear RNA export factor 1,transcription export complex|intracellular|cell|nucleus|nuclear pore|cytoplasm|nuclear speck|nuclear inclusion body|,RNA export from nucleus|mRNA export from nucleus|transport|poly(A)+ mRNA export from nucleus|mRNA transport|,nucleotide binding|RNA binding|mRNA binding|nucleocytoplasmic transporter activity|protein binding|poly(A) RNA binding|,7,-0.5,8.3,7,-1,2.41,-0.6,9.01,-9.01,0.252,0,0,-2,1.1
ENSMUSG00000032399,RPL4,ribosomal protein L4,nucleus|nucleolus|cytoplasm|ribosome|large ribosomal subunit|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,structural constituent of ribosome|protein binding|poly(A) RNA binding|,3,0.2,0.585,3,1,10.1,1,8.92,8.92,0.253,0,0,0.5,2
ENSMUSG00000039163,CMC1,COX assembly mitochondrial protein 1,mitochondrion|,biological_process|,molecular_function|metal ion binding|,10,-0.8,9.51,10,-0.2,0.407,-0.3,8.83,-8.83,0.254,0,0,-1.4,-0.1
ENSMUSG00000060716,PLEKHH1,"pleckstrin homology domain containing, family H (with MyTH4 domain) member 1",cytoskeleton|,biological_process|,molecular_function|,10,-0.9,11.5,10,0.2,0.483,-0.8,8.68,-8.68,0.256,0,0,-1.9,-0.3
ENSMUSG00000020859,SPAG9,sperm associated antigen 9,cytoplasm|cytoplasm|perinuclear region of cytoplasm|extracellular vesicular exosome|,"activation of MAPK activity|activation of JUN kinase activity|positive regulation of cell migration|retrograde transport, endosome to Golgi|positive regulation of MAPK cascade|positive regulation of neuron differentiation|striated muscle cell differentiation|protein homooligomerization|negative regulation of protein homodimerization activity|",protein binding|JUN kinase binding|kinesin binding|mitogen-activated protein kinase p38 binding|,10,0.5,7.32,10,0.3,3.4,0.5,8.65,8.65,0.257,0,0,0.1,0.9
ENSMUSG00000024082,NDUFAF7,NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 7,extracellular space|mitochondrion|mitochondrion|,mitochondrial respiratory chain complex I assembly|,enzyme binding|,10,0.4,4.17,10,1.2,8.87,0.6,8.51,8.51,0.259,0,0,0.3,1.8
ENSMUSG00000073481,2-Mar,mitochondrial amidoxime reducing component 2,mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|peroxisome|membrane|extracellular vesicular exosome|,nitrate metabolic process|oxidation-reduction process|,catalytic activity|N-ethylmaleimide reductase activity|nitrate reductase activity|oxidoreductase activity|molybdenum ion binding|pyridoxal phosphate binding|molybdopterin cofactor binding|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.3,3.59,10,0.9,6.48,0.4,8.48,8.48,0.259,0,0,0.2,1.4
ENSMUSG00000019173,RAB5C,"RAB5C, member RAS oncogene family",lysosomal membrane|endosome|lipid particle|plasma membrane|membrane|endocytic vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|extracellular vesicular exosome|,GTP catabolic process|transport|endosome organization|small GTPase mediated signal transduction|protein transport|regulation of endocytosis|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|,10,-0.5,3.03,10,0.9,8.75,0.8,8.47,8.47,0.259,0,0,-0.4,2
ENSMUSG00000026248,MRPL44,mitochondrial ribosomal protein L44,mitochondrion|ribosome|ribonucleoprotein complex|,RNA processing|mitochondrial translational elongation|,RNA binding|nuclease activity|endonuclease activity|ribonuclease III activity|bidentate ribonuclease III activity|hydrolase activity|poly(A) RNA binding|,9,-0.6,4.85,9,-1.1,4.62,-0.7,8.1,-8.1,0.265,0,0,-2,-0.1
ENSMUSG00000068523,GNG5,"guanine nucleotide binding protein (G protein), gamma 5",mitochondrion|membrane|extracellular vesicular exosome|,None,PDZ domain binding|,9,0.6,4.07,9,0.6,4.34,0.6,8.06,8.06,0.266,0,0,0.1,1.6
ENSMUSG00000033918,PARL,"presenilin associated, rhomboid-like",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,proteolysis|negative regulation of release of cytochrome c from mitochondria|negative regulation of intrinsic apoptotic signaling pathway|,serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.3,6.95,10,0.5,2.19,0.4,7.92,7.92,0.268,0,0,0.1,1
ENSMUSG00000042410,AGPS,alkylglycerone phosphate synthase,nucleolus|mitochondrion|mitochondrion|peroxisome|peroxisomal membrane|membrane|intracellular membrane-bounded organelle|,lipid metabolic process|lipid biosynthetic process|oxidation-reduction process|,"catalytic activity|alkylglycerone-phosphate synthase activity|UDP-N-acetylmuramate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|transferase activity|flavin adenine dinucleotide binding|",10,-0.3,8.42,10,-0.1,0.218,-0.3,7.91,-7.91,0.268,0,0,-0.7,-0.1
ENSMUSG00000028357,KIF12,kinesin family member 12,cytoplasm|cytoskeleton|kinesin complex|microtubule|extracellular vesicular exosome|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,0,0,10,-1.3,11.1,-1.2,7.82,-7.82,0.269,0,0,-2,-0.2
ENSMUSG00000010392,GOSR1,golgi SNAP receptor complex member 1,Golgi membrane|Golgi membrane|Golgi apparatus|cis-Golgi network|membrane|membrane|integral component of membrane|,"transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|retrograde transport, endosome to Golgi|",SNAP receptor activity|,10,0.1,0.00905,10,1.1,9.94,1.1,7.81,7.81,0.27,0,0,0.3,1.9
ENSMUSG00000035351,NUP37,nucleoporin 37,"chromosome, centromeric region|kinetochore|nucleus|nuclear pore|chromosome|nuclear pore outer ring|",transport|cell cycle|chromosome segregation|mitotic nuclear division|protein transport|mRNA transport|cell division|,molecular_function|,10,0.5,6.74,10,0.4,1.54,0.4,7.7,7.7,0.272,0,0,-0.1,1.1
ENSMUSG00000058966,FAM57B,"family with sequence similarity 57, member B",endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,lipid metabolic process|negative regulation of fat cell differentiation|ceramide biosynthetic process|,sphingosine N-acyltransferase activity|,10,0.5,9.59,10,-0.5,1.92,0.5,7.69,7.69,0.272,0,0,0.1,1.4
ENSMUSG00000036285,NOA1,nitric oxide associated 1,mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|extrinsic component of mitochondrial inner membrane|,GTP catabolic process|apoptotic process|regulation of cell death|regulation of cell death|regulation of cell death|mitochondrial translation|ribosome biogenesis|regulation of cellular respiration|regulation of cellular respiration|,nucleotide binding|GTPase activity|GTP binding|poly(A) RNA binding|,10,0.6,4.13,10,0.4,4.32,0.6,7.65,7.65,0.273,0,0,0.1,1.4
ENSMUSG00000027367,STARD7,START domain containing 7,cellular_component|mitochondrion|,biological_process|,molecular_function|lipid binding|,10,-0.4,8.17,10,-0.1,0.0545,-0.3,7.62,-7.62,0.273,0,0,-1,-0.1
ENSMUSG00000031353,RBBP7,retinoblastoma binding protein 7,nucleus|nucleus|NuRD complex|NuRD complex|ESC/E(Z) complex|,"negative regulation of transcription from RNA polymerase II promoter|DNA replication|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|negative regulation of cell growth|negative regulation of transcription, DNA-templated|cellular heat acclimation|cellular heat acclimation|",RNA binding|protein binding|,10,0.8,7.38,10,0.4,1.19,0.4,7.56,7.56,0.274,0,0,0.2,1.6
ENSMUSG00000041632,MRPS27,mitochondrial ribosomal protein S27,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,10,-0.3,3.71,10,-0.6,4.9,-0.4,7.56,-7.56,0.274,0,0,-1.3,0.3
ENSMUSG00000039089,L3MBTL3,l(3)mbt-like 3 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|myeloid cell differentiation|myeloid cell differentiation|macrophage differentiation|granulocyte differentiation|erythrocyte maturation|",protein binding|,10,0.4,6,10,0.3,1.79,0.4,7.36,7.36,0.278,0,0,0.1,0.9
ENSMUSG00000032263,BCKDHB,"branched chain ketoacid dehydrogenase E1, beta polypeptide",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial alpha-ketoglutarate dehydrogenase complex|,metabolic process|cellular amino acid catabolic process|branched-chain amino acid catabolic process|oxidation-reduction process|,catalytic activity|alpha-ketoacid dehydrogenase activity|3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity|oxidoreductase activity|protein complex binding|,10,-0.7,4.72,10,-0.8,2.98,-0.7,7.26,-7.26,0.28,0,0,-1.7,-0.2
ENSMUSG00000024236,SVIL,supervillin,nucleus|cytoplasm|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|cell junction|cell projection|costamere|,cytoskeleton organization|skeletal muscle tissue development|,actin binding|actin filament binding|,10,0.3,5.93,10,0.4,1.65,0.3,7.23,7.23,0.281,0,0,-0.1,1
ENSMUSG00000052337,IMMT,"inner membrane protein, mitochondrial",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|membrane|integral component of membrane|,mitochondrial calcium ion homeostasis|,protein binding|poly(A) RNA binding|,10,-0.4,4.97,10,-0.5,2.71,-0.4,7.21,-7.21,0.281,0,0,-1.2,-0.1
ENSMUSG00000022668,GTPBP8,GTP-binding protein 8 (putative),mitochondrion|,barrier septum assembly|biological_process|,nucleotide binding|molecular_function|GTP binding|metal ion binding|,10,0.5,1.09,10,0.4,6.38,0.4,7.18,7.18,0.282,0,0,0,1.2
ENSMUSG00000031641,CBR4,carbonyl reductase 4,mitochondrion|mitochondrial matrix|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|metabolic process|daunorubicin metabolic process|doxorubicin metabolic process|protein homotetramerization|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|NAD(P)H dehydrogenase (quinone) activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|N-ethylmaleimide reductase activity|NADPH dehydrogenase (quinone) activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|quinone binding|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|epoxyqueuosine reductase activity|NADPH binding|",10,0.5,5.9,10,0.9,1.76,0.5,7.1,7.1,0.284,0,0,0.1,1.3
ENSMUSG00000002319,IPO4,importin 4,nuclear chromatin|intracellular|cell|nucleus|cytoplasm|membrane|protein complex|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|ribosomal protein import into nucleus|transport|intracellular protein transport|protein transport|ribosome biogenesis|,protein binding|Ran GTPase binding|,10,0.4,6.2,10,0.2,1.25,0.4,6.93,6.93,0.288,0,0,0.1,1
ENSMUSG00000034203,CHCHD4,coiled-coil-helix-coiled-coil-helix domain containing 4,mitochondrion|mitochondrial intermembrane space|,transport|protein transport|protein maturation by protein folding|protein import into mitochondrial intermembrane space|'de novo' posttranslational protein folding|oxidation-reduction process|,protein disulfide oxidoreductase activity|oxidoreductase activity|,10,-0.8,4.34,9,-0.8,2.91,-0.8,6.92,-6.92,0.288,0,0,-1.9,-0.2
ENSMUSG00000028236,SDR16C5,"short chain dehydrogenase/reductase family 16C, member 5",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,metabolic process|retinol metabolic process|retinal metabolic process|keratinocyte proliferation|oxidation-reduction process|,retinol dehydrogenase activity|oxidoreductase activity|,10,-0.8,7.06,10,-0.3,1.63,-0.5,6.86,-6.86,0.289,0,0,-1.5,-0.1
ENSMUSG00000007827,ANKRD26,ankyrin repeat domain 26,centrosome|actin filament|,regulation of lipid metabolic process|regulation of fatty acid metabolic process|negative regulation of multicellular organism growth|glucose homeostasis|negative regulation of fat cell differentiation|negative regulation of organ growth|negative regulation of insulin receptor signaling pathway|regulation of feeding behavior|negative regulation of ERK1 and ERK2 cascade|,protein binding|,10,0.4,7.47,10,0.2,0.292,0.4,6.86,6.86,0.289,0,0,0,1
ENSMUSG00000031949,ADAT1,"adenosine deaminase, tRNA-specific 1",cellular_component|,RNA processing|tRNA processing|,RNA binding|adenosine deaminase activity|tRNA-specific adenosine deaminase activity|tRNA-specific adenosine deaminase activity|hydrolase activity|metal ion binding|,9,0.5,6.8,9,0.2,0.983,0.5,6.73,6.73,0.293,0,0,0.1,1.2
ENSMUSG00000024870,RAB1B,"RAB1B, member RAS oncogene family",cytoplasm|mitochondrion|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|extracellular vesicular exosome|,transport|small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTP binding|,10,0.2,1.2,10,0.4,6.12,0.3,6.67,6.67,0.294,0,0,0,0.9
ENSMUSG00000027305,NDUFAF1,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1",cytoplasm|mitochondrion|,biological_process|,molecular_function|NADH dehydrogenase (ubiquinone) activity|,10,0.3,2.81,10,-1.4,10.1,-1.4,6.66,-6.66,0.295,0,0,-2,0.3
ENSMUSG00000034308,SDR42E1,"short chain dehydrogenase/reductase family 42E, member 1",cellular_component|membrane|integral component of membrane|,steroid biosynthetic process|biological_process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|molecular_function|3-beta-hydroxy-delta5-steroid dehydrogenase activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.7,6.57,10,0.4,0.456,0.3,6.55,6.55,0.298,0,0,0.1,1.4
ENSMUSG00000021751,ACOX2,"acyl-Coenzyme A oxidase 2, branched chain",peroxisome|,lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|metabolic process|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|acyl-CoA oxidase activity|receptor binding|fatty acid binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity|flavin adenine dinucleotide binding|",9,0.3,1.79,9,0.4,4.87,0.4,6.35,6.35,0.303,0,0,-0.2,1.1
ENSMUSG00000060771,TSGA10,testis specific 10,nucleus|cytoplasm|cytoplasm|membrane|motile cilium|neuron projection|,cell projection assembly|,structural molecule activity|protein binding|,10,-0.9,9.42,10,0,0,-0.9,6.34,-6.34,0.304,0,0,-1.8,-0.1
ENSMUSG00000021973,MICU2,mitochondrial calcium uptake 2,mitochondrion|mitochondrion|mitochondrial intermembrane space|calcium channel complex|uniplex complex|,mitochondrial calcium ion transport|mitochondrial calcium ion transport|positive regulation of mitochondrial calcium ion concentration|negative regulation of mitochondrial calcium ion concentration|,calcium ion binding|protein binding|protein heterodimerization activity|protein heterodimerization activity|,9,0.3,4.75,10,0.4,1.95,0.3,6.27,6.27,0.305,0,0,-0.1,1
ENSMUSG00000017686,RHOT1,"ras homolog gene family, member T1",intracellular|mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|,small GTPase mediated signal transduction|cellular homeostasis|mitochondrion transport along microtubule|mitochondrial outer membrane permeabilization|,nucleotide binding|GTPase activity|calcium ion binding|GTP binding|hydrolase activity|metal ion binding|,10,0.5,8.69,10,-1.2,5.26,0.5,6.27,6.27,0.305,0,0,-1.7,1.3
ENSMUSG00000063838,CDC42EP5,CDC42 effector protein (Rho GTPase binding) 5,cytoplasm|cytoplasm|cytoskeleton|plasma membrane|membrane|,JNK cascade|Rho protein signal transduction|regulation of cell shape|positive regulation of actin filament polymerization|positive regulation of pseudopodium assembly|,protein binding|GTP-Rho binding|,9,0.1,0.322,10,-1.4,9.73,-1.4,6.26,-6.26,0.306,0,0,-2,-0.2
ENSMUSG00000063200,NOL7,nucleolar protein 7,nucleus|,biological_process|,poly(A) RNA binding|,10,0.4,4.02,10,0.3,2.62,0.4,6.19,6.19,0.308,0,0,-0.3,1.3
ENSMUSG00000038520,TBC1D17,"TBC1 domain family, member 17",cellular_component|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,-0.2,2.84,10,0.4,7.97,0.4,6.09,6.09,0.311,0,0,-0.4,1
ENSMUSG00000033061,RESP18,regulated endocrine-specific protein 18,extracellular region|endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|secretory granule|perikaryon|rough endoplasmic reticulum lumen|,in utero embryonic development|,molecular_function|,10,0.4,5.03,10,-0.7,3.75,0.4,6.07,6.07,0.312,0,0,-1.2,1.3
ENSMUSG00000037486,ASXL2,additional sex combs like 2 (Drosophila),nuclear chromatin|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|adult heart development|positive regulation of peroxisome proliferator activated receptor signaling pathway|positive regulation of fat cell differentiation|positive regulation of osteoclast differentiation|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|positive regulation of bone mineralization involved in bone maturation|positive regulation of histone H3-K27 trimethylation|",DNA binding|peroxisome proliferator activated receptor binding|metal ion binding|,10,0.4,5.86,10,0.2,0.612,0.4,5.94,5.94,0.316,0,0,0,1
ENSMUSG00000053797,KRT16,keratin 16,nucleus|cytoskeleton|intermediate filament|extracellular vesicular exosome|,aging|negative regulation of cell migration|hair cycle|intermediate filament cytoskeleton organization|,structural molecule activity|structural constituent of cytoskeleton|protein binding|,10,0.2,2.16,10,0.5,5.18,0.4,5.89,5.89,0.317,0,0,0,1.2
ENSMUSG00000058600,RPL30,ribosomal protein L30,intracellular|nucleus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,structural constituent of ribosome|poly(A) RNA binding|,4,0.5,4.37,4,1,3.24,0.6,5.85,5.85,0.319,0,0,-0.6,2
ENSMUSG00000028975,PEX14,peroxisomal biogenesis factor 14,intracellular|nucleolus|peroxisome|peroxisome|peroxisomal membrane|peroxisomal membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|protein complex|,"protein complex assembly|transport|peroxisome organization|protein transport|protein import into peroxisome matrix|protein import into peroxisome matrix, docking|protein import into peroxisome matrix, translocation|negative regulation of protein binding|microtubule anchoring|peroxisome transport along microtubule|negative regulation of sequence-specific DNA binding transcription factor activity|protein import into peroxisome matrix, substrate release|negative regulation of transcription, DNA-templated|protein homooligomerization|negative regulation of protein homotetramerization|",transcription corepressor activity|receptor binding|microtubule binding|protein N-terminus binding|beta-tubulin binding|,9,0.3,4.71,9,0.9,3.12,0.5,5.83,5.83,0.319,0,0,0.1,1.5
ENSMUSG00000022339,EBAG9,estrogen receptor-binding fragment-associated gene 9,Golgi apparatus|plasma membrane|focal adhesion|membrane|integral component of membrane|secretory granule|,apoptotic process|,None,10,-0.3,3.04,10,-0.9,6.18,-0.5,5.74,-5.74,0.322,0,0,-1.7,-0.1
ENSMUSG00000042719,NAA25,"N(alpha)-acetyltransferase 25, NatB auxiliary subunit",cytoplasm|,biological_process|,molecular_function|,6,0.8,6.52,7,-0.2,0.207,0.6,5.73,5.73,0.323,0,0,0,2
ENSMUSG00000022805,MAATS1,"MYCBP-associated, testis expressed 1",cellular_component|cytoplasm|mitochondrion|,biological_process|,molecular_function|,10,-0.4,6.68,10,0.7,2.64,-0.4,5.7,-5.7,0.324,0,0,-1.2,1
ENSMUSG00000070283,NDUFAF3,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3",nucleus|mitochondrion|mitochondrial inner membrane|membrane|,mitochondrial respiratory chain complex I assembly|,molecular_function|,10,0.3,5.07,10,0.9,1.02,0.4,5.67,5.67,0.325,0,0,-0.2,1.3
ENSMUSG00000027086,FASTKD1,FAST kinase domains 1,mitochondrion|mitochondrion|,cellular respiration|,protein kinase activity|poly(A) RNA binding|,10,-0.3,6.08,10,-0.1,0.109,-0.3,5.64,-5.64,0.326,0,0,-1.1,0.1
ENSMUSG00000063273,NAA15,"N(alpha)-acetyltransferase 15, NatA auxiliary subunit",nucleus|transcription factor complex|cytoplasm|cytoplasm|membrane|NatA complex|,"angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|N-terminal protein amino acid acetylation|multicellular organismal development|cell differentiation|negative regulation of apoptotic process|positive regulation of transcription, DNA-templated|protein stabilization|",protein binding|N-acetyltransferase activity|acetyltransferase activity|ribosome binding|ribosome binding|poly(A) RNA binding|,6,0.7,2.48,8,1.1,4.01,0.7,5.51,5.51,0.331,0,0,-0.8,2
ENSMUSG00000041235,CHD7,chromodomain helicase DNA binding protein 7,nucleus|,"skeletal system development|blood vessel development|in utero embryonic development|in utero embryonic development|heart morphogenesis|heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|central nervous system development|adult heart development|sensory perception of sound|locomotory behavior|adult walking behavior|blood circulation|chromatin modification|cranial nerve development|olfactory nerve development|olfactory bulb development|T cell differentiation|female genitalia development|embryonic hindlimb morphogenesis|positive regulation of multicellular organism growth|olfactory behavior|ear morphogenesis|inner ear morphogenesis|inner ear morphogenesis|camera-type eye development|nose development|nose development|semicircular canal morphogenesis|genitalia development|artery morphogenesis|regulation of neurogenesis|cognition|palate development|palate development|retina development in camera-type eye|regulation of growth hormone secretion|limb development|face development|epithelium development|","nucleotide binding|DNA binding|chromatin binding|helicase activity|protein binding|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|",10,-0.3,5.77,10,-0.1,0.211,-0.3,5.45,-5.45,0.333,0,0,-0.9,0.3
ENSMUSG00000037949,ANO10,anoctamin 10,intracellular|intracellular|plasma membrane|plasma membrane|membrane|membrane|integral component of membrane|,cation transport|chloride transport|chloride transmembrane transport|,calcium activated cation channel activity|,10,0.2,0.291,10,-0.7,7.2,-0.5,5.43,-5.43,0.334,0,0,-1.7,-0.1
ENSMUSG00000028906,EPB4.1,erythrocyte protein band 4.1,nucleus|cytoplasm|cytoskeleton|actin cytoskeleton|membrane|extrinsic component of membrane|cortical cytoskeleton|cortical cytoskeleton|protein complex|,regulation of cell shape|actin cytoskeleton organization|cortical actin cytoskeleton organization|positive regulation of protein binding|positive regulation of protein binding|,actin binding|structural molecule activity|calmodulin binding|1-phosphatidylinositol binding|cytoskeletal protein binding|spectrin binding|spectrin binding|,10,0.2,1.69,10,1,7.24,0.9,5.39,5.39,0.335,0,0,0.1,1.7
ENSMUSG00000075467,DNLZ,DNL-type zinc finger,mitochondrion|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,8,-0.7,3.29,8,0.5,4.83,0.6,5.38,5.38,0.336,0,0,-1.2,1.6
ENSMUSG00000035585,TSEN34,tRNA splicing endonuclease 34 homolog (S. cerevisiae),tRNA-intron endonuclease complex|cellular_component|nucleus|,"tRNA-type intron splice site recognition and cleavage|tRNA splicing, via endonucleolytic cleavage and ligation|mRNA processing|tRNA processing|",tRNA-intron endonuclease activity|nucleic acid binding|nuclease activity|protein binding|lyase activity|,9,-0.7,2.94,8,1,5.42,0.8,5.32,5.32,0.338,0,0,-0.7,2
ENSMUSG00000004842,POU1F1,"POU domain, class 1, transcription factor 1",nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|cell fate specification|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|determination of adult lifespan|pituitary gland development|adenohypophysis development|B cell differentiation|positive regulation of inositol trisphosphate biosynthetic process|positive regulation of multicellular organism growth|regulation of insulin-like growth factor receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|nuclear transport|somatotropin secreting cell differentiation|somatotropin secreting cell development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription coactivator activity|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|transcription factor binding|sequence-specific DNA binding|,10,0.1,0.892,10,1.2,8.31,1.2,5.3,5.3,0.339,0,0,0.1,1.9
ENSMUSG00000015143,ACTN1,"actinin, alpha 1",stress fiber|stress fiber|stress fiber|extracellular space|nucleus|cytoplasm|cytoskeleton|plasma membrane|fascia adherens|focal adhesion|focal adhesion|membrane|Z disc|cell junction|secretory granule|cortical cytoskeleton|cortical actin cytoskeleton|dense core granule membrane|cell projection|dendritic spine|extracellular vesicular exosome|,cortical cytoskeleton organization|focal adhesion assembly|actin filament bundle assembly|negative regulation of cellular component movement|actin crosslink formation|,double-stranded RNA binding|actin binding|integrin binding|calcium ion binding|protein binding|vinculin binding|protein domain specific binding|protein homodimerization activity|ion channel binding|metal ion binding|actin filament binding|,10,0.3,2.95,10,0.6,3.53,0.3,5.29,5.29,0.339,0,0,0,1.4
ENSMUSG00000015533,ITGA2,integrin alpha 2,nucleus|plasma membrane|focal adhesion|integrin complex|external side of plasma membrane|cell surface|membrane|integral component of membrane|axon|cell projection|axon terminus|basal part of cell|perinuclear region of cytoplasm|,"positive regulation of leukocyte migration|substrate-dependent cell migration|hypotonic response|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|positive regulation of epithelial cell migration|positive regulation of alkaline phosphatase activity|positive regulation of smooth muscle cell migration|positive regulation of cell projection organization|cell-substrate adhesion|positive regulation of collagen biosynthetic process|positive regulation of collagen binding|cell adhesion mediated by integrin|collagen-activated signaling pathway|positive regulation of DNA binding|skin morphogenesis|establishment of protein localization|positive regulation of translation|positive regulation of cell adhesion|positive regulation of smooth muscle contraction|focal adhesion assembly|positive regulation of smooth muscle cell proliferation|positive regulation of inflammatory response|positive regulation of positive chemotaxis|detection of mechanical stimulus involved in sensory perception of pain|positive regulation of transmission of nerve impulse|positive regulation of phagocytosis, engulfment|",integrin binding|collagen binding|protein complex binding|collagen receptor activity|laminin binding|metal ion binding|protein heterodimerization activity|,10,0.2,4.18,10,0.9,1.52,0.2,5.28,5.28,0.339,0,0,0,1.4
ENSMUSG00000027637,1110008F13RIK,RIKEN cDNA 1110008F13 gene,mitochondrion|,biological_process|,molecular_function|,10,0.3,4.9,10,0.4,0.635,0.4,5.28,5.28,0.339,0,0,-0.2,1
ENSMUSG00000094483,PURB,purine rich element binding protein B,nucleus|nucleus|DNA replication factor A complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cell proliferation|negative regulation of translation|cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|","translation repressor activity, nucleic acid binding|DNA binding|double-stranded DNA binding|single-stranded DNA binding|single-stranded DNA binding|sequence-specific DNA binding transcription factor activity|mRNA binding|protein binding|transcription factor binding|purine-rich negative regulatory element binding|poly(A) RNA binding|SMAD binding|",10,0.2,2.4,10,0.4,3.76,0.3,5.28,5.28,0.339,0,0,0,0.9
ENSMUSG00000022452,SMDT1,single-pass membrane protein with aspartate rich tail 1,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial inner membrane|uniplex complex|,transport|ion transport|calcium ion transport|mitochondrial calcium ion transport|calcium ion import into mitochondrion|mitochondrial calcium ion homeostasis|,molecular_function|,10,0.5,3.09,10,1.1,2.69,0.5,5.26,5.26,0.34,0,0,0,1.7
ENSMUSG00000063804,LIN28B,lin-28 homolog B (C. elegans),nucleus|cytoplasm|,"regulation of transcription, DNA-templated|miRNA catabolic process|gene silencing by RNA|pre-miRNA processing|RNA 3'-end processing|",nucleic acid binding|DNA binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.5,5.83,10,-0.1,0.11,-0.4,5.11,-5.11,0.347,0,0,-1.4,0.1
ENSMUSG00000017754,PLTP,phospholipid transfer protein,extracellular region|extracellular space|,transport|lipid transport|vitamin E biosynthetic process|sperm motility|,lipid binding|,10,0.6,3.22,10,1.1,2.74,0.6,5.04,5.04,0.35,0,0,0.2,1.9
ENSMUSG00000024614,TMX3,thioredoxin-related transmembrane protein 3,endoplasmic reticulum|cell surface|cell surface|membrane|integral component of membrane|,protein folding|response to endoplasmic reticulum stress|cell redox homeostasis|,protein disulfide isomerase activity|isomerase activity|,10,0.7,5.95,10,0.1,0.521,0.3,5.04,5.04,0.35,0,0,0,1.6
ENSMUSG00000008682,RPL10,ribosomal protein L10,cytoplasm|endoplasmic reticulum|membrane|cytosolic large ribosomal subunit|,translation|,structural constituent of ribosome|poly(A) RNA binding|,3,0.8,4.31,2,0.4,1.59,0.8,5.04,5.04,0.35,0,0,0,2
ENSMUSG00000049517,RPS23,ribosomal protein S23,intracellular|nucleolus|cytoplasm|ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,2,0.5,5.26,1,0.1,0.216,0.5,5.02,5.02,0.351,0,0,-0.4,2
ENSMUSG00000027800,TM4SF1,transmembrane 4 superfamily member 1,integral component of plasma membrane|membrane|integral component of membrane|,None,None,10,0.7,3.29,10,1,2.42,0.8,5,5,0.351,0,0,0.1,1.8
ENSMUSG00000041220,ELOVL6,"ELOVL family member 6, elongation of long chain fatty acids (yeast)",endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,"lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation, saturated fatty acid|fatty acid elongation|long-chain fatty acid biosynthetic process|","fatty acid elongase activity|transferase activity|transferase activity, transferring acyl groups other than amino-acyl groups|",10,0.5,2.04,10,1.1,3.32,0.5,4.96,4.96,0.353,0,0,0,1.7
ENSMUSG00000018920,CXCL16,chemokine (C-X-C motif) ligand 16,extracellular space|membrane|integral component of membrane|,receptor-mediated endocytosis|chemotaxis|positive regulation of cell growth|positive regulation of cell migration|response to cytokine|response to interferon-gamma|response to tumor necrosis factor|lymphocyte chemotaxis|cell chemotaxis|,low-density lipoprotein receptor activity|scavenger receptor activity|cytokine activity|chemokine activity|chemokine activity|,10,-0.9,7.3,9,0.1,0.0109,-0.8,4.91,-4.91,0.355,0,0,-1.9,-0.1
ENSMUSG00000023367,TMEM176A,transmembrane protein 176A,membrane|integral component of membrane|,negative regulation of dendritic cell differentiation|,protein binding|,10,0.5,1.45,10,-0.5,5.23,-0.5,4.88,-4.88,0.357,0,0,-1.4,1.6
ENSMUSG00000027710,ACAD9,"acyl-Coenzyme A dehydrogenase family, member 9",nucleus|mitochondrion|mitochondrion|dendrite|,metabolic process|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|short-branched-chain-acyl-CoA dehydrogenase activity|very-long-chain-acyl-CoA dehydrogenase activity|4-methyloctanoyl-CoA dehydrogenase activity|naphthyl-2-methyl-succinyl-CoA dehydrogenase activity|2-methylhexanoyl-CoA dehydrogenase activity|propionyl-CoA dehydrogenase activity|thiol-driven fumarate reductase activity|flavin adenine dinucleotide binding|coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity|coenzyme F420-dependent 2,4-dinitrophenol reductase activity|medium-chain-acyl-CoA dehydrogenase activity|",10,0.3,3.71,10,0.4,1.5,0.3,4.85,4.85,0.358,0,0,-0.1,1.3
ENSMUSG00000063659,ZBTB18,zinc finger and BTB domain containing 18,nucleus|nucleus|microtubule cytoskeleton|intercellular bridge|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|skeletal muscle tissue development|cerebellum development|hippocampus development|cerebral cortex development|negative regulation of transcription, DNA-templated|neuron development|homeostasis of number of cells|regulation of cell division|",nucleic acid binding|DNA binding|sequence-specific DNA binding|metal ion binding|,10,0.2,2.36,10,0.2,2.72,0.2,4.8,4.8,0.361,0,0,-0.1,1
ENSMUSG00000004317,CLCN5,chloride channel 5,lysosomal membrane|endosome|Golgi apparatus|plasma membrane|membrane|integral component of membrane|apical part of cell|apical part of cell|,transport|ion transport|chloride transport|endocytosis|regulation of ion transmembrane transport|regulation of anion transport|transmembrane transport|chloride transmembrane transport|,nucleotide binding|ion channel activity|voltage-gated chloride channel activity|ATP binding|antiporter activity|adenyl nucleotide binding|,10,-0.3,6.63,10,0,0,-0.3,4.76,-4.76,0.362,0,0,-1.1,0.2
ENSMUSG00000020330,HMMR,hyaluronan mediated motility receptor (RHAMM),cytoplasm|membrane|,None,hyaluronic acid binding|,10,0.6,3.62,10,0.2,2.54,0.4,4.72,4.72,0.364,0,0,-0.1,1.3
ENSMUSG00000030825,HSD17B14,hydroxysteroid (17-beta) dehydrogenase 14,cytosol|,steroid catabolic process|oxidation-reduction process|,estradiol 17-beta-dehydrogenase activity|testosterone 17-beta-dehydrogenase (NADP+) activity|,10,-0.3,5.81,10,0.2,0.665,-0.3,4.71,-4.71,0.365,0,0,-1.1,0.5
ENSMUSG00000009418,NAV1,neuron navigator 1,cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|,microtubule bundle formation|neuron migration|multicellular organismal development|nervous system development|cell differentiation|,nucleotide binding|ATP binding|,10,-0.8,7.71,10,0,0,-0.8,4.68,-4.68,0.366,0,0,-2,-0.1
ENSMUSG00000057497,FAM136A,"family with sequence similarity 136, member A",cytoplasm|mitochondrion|,biological_process|,molecular_function|,10,0.4,6.88,10,-0.3,1.36,0.3,4.64,4.64,0.368,0,0,-0.7,1.2
ENSMUSG00000019814,LTV1,LTV1 homolog (S. cerevisiae),nucleus|cytoplasm|,None,None,9,0.2,3.14,10,1,2.61,0.3,4.61,4.61,0.369,0,0,-0.7,1.7
ENSMUSG00000036323,SRP72,signal recognition particle 72,"nucleolus|cytoplasm|endoplasmic reticulum|signal recognition particle, endoplasmic reticulum targeting|signal recognition particle, endoplasmic reticulum targeting|ribonucleoprotein complex|",SRP-dependent cotranslational protein targeting to membrane|response to drug|,signal recognition particle binding|poly(A) RNA binding|,10,-0.7,5.66,10,0.4,4.17,0.5,4.6,4.6,0.37,0,0,-1.6,1.2
ENSMUSG00000079641,RPL39,ribosomal protein L39,extracellular space|intracellular|ribosome|cytosolic large ribosomal subunit|ribonucleoprotein complex|,innate immune response in mucosa|translation|antibacterial humoral response|defense response to Gram-positive bacterium|,molecular_function|structural constituent of ribosome|,1,-0.6,5.01,1,1.3,5.47,1.3,4.52,4.52,0.373,0,0,-1.8,2
ENSMUSG00000024207,ACSBG2,acyl-CoA synthetase bubblegum family member 2,cytoplasm|cytoplasm|mitochondrion|cytosol|membrane|,long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|multicellular organismal development|spermatogenesis|metabolic process|cell differentiation|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|ATP binding|ligase activity|acyl-CoA hydrolase activity|,10,0.3,0.283,10,0.7,5.26,0.6,4.46,4.46,0.377,0,0,-0.1,1.8
ENSMUSG00000033629,PTPLAD1,protein tyrosine phosphatase-like A domain containing 1,intracellular|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|I-kappaB kinase/NF-kappaB signaling|JNK cascade|Rho protein signal transduction|,protein binding|lyase activity|,10,0.7,7.09,10,-0.7,1.17,0.7,4.42,4.42,0.379,0,0,-0.4,2
ENSMUSG00000031985,GNPAT,glyceronephosphate O-acyltransferase,mitochondrion|peroxisome|peroxisomal membrane|peroxisomal matrix|membrane|membrane|,synapse assembly|metabolic process|ether lipid biosynthetic process|ether lipid biosynthetic process|ether lipid biosynthetic process|cerebellum morphogenesis|paranodal junction assembly|myelination|cellular lipid metabolic process|membrane organization|,"catalytic activity|receptor binding|protein binding|O-acyltransferase activity|glycerone-phosphate O-acyltransferase activity|glycerone-phosphate O-acyltransferase activity|glycerone-phosphate O-acyltransferase activity|palmitoyl-CoA hydrolase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.3,2.74,10,-0.3,1.9,-0.3,4.38,-4.38,0.381,0,0,-1.2,0.1
ENSMUSG00000042460,C1GALT1,"core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1",membrane|integral component of membrane|,"angiogenesis|angiogenesis|kidney development|protein O-linked glycosylation|multicellular organismal development|O-glycan processing|O-glycan processing, core 1|cell differentiation|intestinal epithelial cell development|","galactosyltransferase activity|glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0.7,5.27,10,-0.9,1.98,0.6,4.36,4.36,0.382,0,0,-1,1.8
ENSMUSG00000020116,PNO1,partner of NOB1 homolog (S. cerevisiae),nucleus|nucleolus|,biological_process|,RNA binding|poly(A) RNA binding|,8,0.5,1.56,9,-0.4,3.56,-0.5,4.33,-4.33,0.383,0,0,-1.3,1.5
ENSMUSG00000022555,DGAT1,diacylglycerol O-acyltransferase 1,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|intracellular membrane-bounded organelle|,triglyceride biosynthetic process|triglyceride biosynthetic process|lipid storage|insulin secretion|very-low-density lipoprotein particle assembly|long-chain fatty-acyl-CoA metabolic process|diacylglycerol metabolic process|glycerolipid metabolic process|fatty acid homeostasis|,"2-acylglycerol O-acyltransferase activity|diacylglycerol O-acyltransferase activity|diacylglycerol O-acyltransferase activity|fatty acid binding|O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|diacylglycerol binding|retinol O-fatty-acyltransferase activity|",10,-0.8,4,10,1,7.53,0.9,4.27,4.27,0.387,0,0,-1.2,2
ENSMUSG00000013936,MYL2,"myosin, light polypeptide 2, regulatory, cardiac, slow",cytoplasm|cytoskeleton|actin cytoskeleton|myosin complex|myofibril|myofibril|contractile fiber|,heart morphogenesis|heart development|post-embryonic development|negative regulation of cell growth|muscle cell fate specification|muscle fiber development|cardiac myofibril assembly|ventricular cardiac muscle tissue morphogenesis|heart contraction|cardiac muscle contraction|cardiac muscle contraction|,actin monomer binding|calcium ion binding|metal ion binding|,10,-0.4,3.16,10,-0.3,1.48,-0.4,4.24,-4.24,0.388,0,0,-1.4,0.2
ENSMUSG00000078695,CISD3,CDGSH iron sulfur domain 3,mitochondrion|mitochondrion|intracellular membrane-bounded organelle|,biological_process|,"metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,0.2,1.74,10,0.3,2.86,0.2,4.24,4.24,0.388,0,0,-0.2,1.3
ENSMUSG00000020440,ARF5,ADP-ribosylation factor 5,intracellular|cytoplasm|Golgi apparatus|plasma membrane|,transport|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|,nucleotide binding|protein binding|GTP binding|,10,-0.4,5.65,10,0.1,0.15,-0.4,4.23,-4.23,0.389,0,0,-1.3,0.4
ENSMUSG00000061086,MYL4,"myosin, light polypeptide 4",myosin complex|A band|,regulation of the force of heart contraction|positive regulation of ATPase activity|cardiac muscle contraction|,actin monomer binding|calcium ion binding|actin filament binding|,10,0.3,3.14,10,1.2,2.02,0.3,4.19,4.19,0.391,0,0,-0.1,1.6
ENSMUSG00000002767,MRPL2,mitochondrial ribosomal protein L2,intracellular|mitochondrion|mitochondrial large ribosomal subunit|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,0.7,5.41,10,0.2,0.212,0.6,4.18,4.18,0.391,0,0,-0.2,1.8
ENSMUSG00000021474,SFXN1,sideroflexin 1,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|iron ion transport|iron ion transport|erythrocyte differentiation|iron ion homeostasis|transmembrane transport|,molecular_function|cation transmembrane transporter activity|,10,1,3.19,10,0.4,2.67,0.8,4.18,4.18,0.391,0,0,-0.6,2
ENSMUSG00000025212,SFXN3,sideroflexin 3,mitochondrion|mitochondrion|mitochondrion|membrane|integral component of membrane|mitochondrial membrane|,transport|ion transport|cation transport|biological_process|iron ion homeostasis|transmembrane transport|,molecular_function|cation transmembrane transporter activity|,10,0.2,2.65,10,0.5,2.15,0.2,4.17,4.17,0.392,0,0,-0.2,1.2
ENSMUSG00000021486,PRELID1,PRELI domain containing 1,nucleus|mitochondrion|mitochondrion|mitochondrial intermembrane space|mitochondrial intermembrane space|protein complex|,transport|lipid transport|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of mitochondrial membrane potential|positive regulation of endopeptidase activity|phospholipid transport|phospholipid transport|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of T cell differentiation|regulation of mitochondrial membrane potential|positive regulation of T cell apoptotic process|negative regulation of release of cytochrome c from mitochondria|regulation of membrane lipid distribution|positive regulation of cellular respiration|negative regulation of apoptotic DNA fragmentation|positive regulation of phospholipid transport|,phosphatidic acid transporter activity|phosphatidic acid transporter activity|,5,-0.4,4.26,6,-0.2,0.451,-0.4,4.16,-4.16,0.392,0,0,-1.8,0.5
ENSMUSG00000031504,RAB20,"RAB20, member RAS oncogene family",Golgi apparatus|membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|phagocytic vesicle|,transport|small GTPase mediated signal transduction|protein transport|phagosome acidification|phagosome-lysosome fusion|,nucleotide binding|GTP binding|,10,-0.3,4.74,10,-0.1,0.0497,-0.3,4.15,-4.15,0.393,0,0,-1.1,0.4
ENSMUSG00000022621,RABL2,"RAB, member RAS oncogene family-like 2",intraciliary transport particle B|sperm midpiece|,small GTPase mediated signal transduction|single fertilization|sperm motility|cilium assembly|,nucleotide binding|protein binding|GTP binding|,10,0.2,0.882,10,1,3.66,0.6,4.11,4.11,0.395,0,0,0,1.8
ENSMUSG00000062151,UNC13C,unc-13 homolog C (C. elegans),cytoplasm|plasma membrane|membrane|cell junction|synapse|,exocytosis|signal transduction|synaptic transmission|intracellular signal transduction|,non-kinase phorbol ester receptor activity|diacylglycerol binding|metal ion binding|,9,-0.1,0.153,9,-0.5,5.71,-0.3,4.11,-4.11,0.395,0,0,-1.5,0.1
ENSMUSG00000068732,TMEM167B,transmembrane protein 167B,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,2.99,10,-0.7,2.65,-0.3,4.11,-4.11,0.395,0,0,-1.9,1
ENSMUSG00000002372,RANBP3,RAN binding protein 3,nucleus|cytoplasm|,transport|biological_process|protein transport|intracellular transport|,R-SMAD binding|,10,0.3,2.61,10,0.2,1.87,0.2,4.07,4.07,0.398,0,0,-0.2,1.1
ENSMUSG00000005628,TMOD4,tropomodulin 4,cytoplasm|cytoskeleton|striated muscle thin filament|,biological_process|,actin binding|tropomyosin binding|,10,-0.2,0.582,10,0.7,6.13,0.7,4.07,4.07,0.398,0,0,-0.9,1.7
ENSMUSG00000028710,ATPAF1,ATP synthase mitochondrial F1 complex assembly factor 1,mitochondrion|,protein complex assembly|biological_process|,molecular_function|,10,-0.3,4.15,10,-0.1,0.534,-0.3,4.02,-4.02,0.401,0,0,-1.2,0.3
ENSMUSG00000053768,CHCHD3,coiled-coil-helix-coiled-coil-helix domain containing 3,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|inner mitochondrial membrane organization|mitochondrial fusion|",RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|protein binding|phosphatase binding|protein complex scaffold|,10,-0.1,0.0656,10,1.1,6.21,0.8,3.99,3.99,0.402,0,0,0,1.8
ENSMUSG00000000711,RAB5B,"RAB5B, member RAS oncogene family",intracellular|endosome|plasma membrane|membrane|endocytic vesicle|extracellular vesicular exosome|,GTP catabolic process|transport|endosome organization|small GTPase mediated signal transduction|protein transport|antigen processing and presentation|regulation of endocytosis|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|GTP-dependent protein binding|,10,0.4,4.49,10,0.1,0.906,0.4,3.98,3.98,0.403,0,0,-0.1,1.4
ENSMUSG00000090862,RPS13,ribosomal protein S13,intracellular|nucleus|nucleolus|ribosome|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|negative regulation of RNA splicing|,mRNA binding|structural constituent of ribosome|poly(A) RNA binding|,3,-0.5,2.84,3,-0.6,1.38,-0.5,3.95,-3.95,0.405,0,0,-2,0.6
ENSMUSG00000044921,RASSF9,Ras association (RalGDS/AF-6) domain family (N-terminal) member 9,endosome|cytosol|trans-Golgi network transport vesicle membrane|recycling endosome|,signal transduction|intracellular transport|,enzyme binding|protein domain specific binding|,10,-0.3,4.66,10,0,0,-0.2,3.91,-3.91,0.407,0,0,-1.1,0.9
ENSMUSG00000035504,REEP6,receptor accessory protein 6,nucleus|membrane|integral component of membrane|apical part of cell|,biological_process|,protein binding|,10,0.2,1.81,10,0.6,2.85,0.3,3.88,3.88,0.409,0,0,-0.4,1.3
ENSMUSG00000029155,SPATA18,spermatogenesis associated 18,cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|sperm flagellum|intracellular membrane-bounded organelle|,cellular response to DNA damage stimulus|multicellular organismal development|spermatogenesis|cell differentiation|cellular response to stress|mitochondrial protein catabolic process|mitochondrion degradation by induced vacuole formation|,molecular_function|,10,0.4,2.14,10,1.1,3.73,0.7,3.87,3.87,0.41,0,0,-0.1,1.8
ENSMUSG00000026820,PTGES2,prostaglandin E synthase 2,nucleus|cytoplasm|mitochondrion|mitochondrion|Golgi apparatus|cytosol|membrane|integral component of membrane|,"prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|cell redox homeostasis|positive regulation of transcription, DNA-templated|secretion|","DNA binding|L-allo-threonine aldolase activity|electron carrier activity|protein disulfide oxidoreductase activity|lyase activity|isomerase activity|2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity|2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity|2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity|2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity|hexulose-6-phosphate synthase activity|4-hydroxy-2-ketopimelate aldolase activity|D-threonine aldolase activity|prostaglandin-E synthase activity|",10,-0.4,5.08,10,0.2,0.531,-0.3,3.85,-3.85,0.411,0,0,-1.5,0.4
ENSMUSG00000021215,NET1,neuroepithelial cell transforming gene 1,nucleus|cytoplasm|plasma membrane|,positive regulation of Rho GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of apoptotic process|myoblast migration|cellular response to hydrogen peroxide|cellular response to ionizing radiation|positive regulation of substrate adhesion-dependent cell spreading|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|GTP-Rho binding|,10,0.2,2.67,10,0.3,1.46,0.2,3.8,3.8,0.414,0,0,-1.6,0.9
ENSMUSG00000021290,2010107E04RIK,RIKEN cDNA 2010107E04 gene,mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.8,3,10,0.2,1.79,0.2,3.8,3.8,0.414,0,0,-0.1,1.6
ENSMUSG00000042644,ITPR3,"inositol 1,4,5-triphosphate receptor 3",nucleus|nuclear envelope|nuclear outer membrane|nucleoplasm|nucleolus|cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|plasma membrane|integral component of plasma membrane|brush border|membrane|membrane|integral component of membrane|dendrite|neuronal cell body|myelin sheath|receptor complex|apical part of cell|perinuclear region of cytoplasm|,transport|ion transport|calcium ion transport|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|memory|inositol phosphate-mediated signaling|inositol phosphate-mediated signaling|sensory perception of bitter taste|sensory perception of sweet taste|sensory perception of umami taste|protein homooligomerization|protein heterooligomerization|response to calcium ion|transmembrane transport|long-term synaptic potentiation|calcium ion transport into cytosol|calcium ion transmembrane transport|cellular response to cAMP|,"inositol hexakisphosphate binding|ion channel activity|intracellular ligand-gated calcium channel activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|calcium channel activity|calcium ion binding|protein binding|phosphatidylinositol binding|inositol 1,3,4,5 tetrakisphosphate binding|inositol 1,4,5 trisphosphate binding|",10,0.7,4.45,10,0,0,0.8,3.78,3.78,0.416,0,0,-0.1,1.9
ENSMUSG00000054808,ACTN4,actinin alpha 4,stress fiber|stress fiber|stress fiber|extracellular space|nucleus|cytoplasm|cytoplasm|cell-cell junction|Z disc|cell junction|ribonucleoprotein complex|cortical cytoskeleton|pseudopodium|neuron projection|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,transport|protein transport|regulation of apoptotic process|positive regulation of pinocytosis|actin filament bundle assembly|negative regulation of cellular component movement|positive regulation of cellular component movement|positive regulation of cellular component movement|positive regulation of cellular component movement|tight junction assembly|protein localization to tight junction|,nucleoside binding|actin binding|calcium ion binding|protein binding|protein complex binding|protein homodimerization activity|poly(A) RNA binding|metal ion binding|protein N-terminus binding|actin filament binding|actin filament binding|,10,0.3,4.51,10,0.1,0.137,0.3,3.76,3.76,0.417,0,0,-0.3,1.2
ENSMUSG00000052921,ARHGEF15,Rho guanine nucleotide exchange factor (GEF) 15,dendrite|cell projection|,positive regulation of Rho GTPase activity|positive regulation of Rho GTPase activity|regulation of Rho protein signal transduction|regulation of catalytic activity|retina vasculature morphogenesis in camera-type eye|negative regulation of synapse maturation|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|,10,0.1,0.624,10,1.4,5.47,0.2,3.75,3.75,0.418,0,0,0,2.9
ENSMUSG00000030219,ERP27,endoplasmic reticulum protein 27,endoplasmic reticulum|,biological_process|,molecular_function|,10,-0.1,0.38,10,-0.4,4.49,-0.3,3.74,-3.74,0.418,0,0,-1.3,0.3
ENSMUSG00000051735,RINL,Ras and Rab interactor-like,ruffle|actin cytoskeleton|cytoplasmic vesicle|cell projection|,transport|endocytosis|protein transport|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|,10,-0.6,3.28,10,-0.3,1.24,-0.4,3.74,-3.74,0.418,0,0,-1.6,0.1
ENSMUSG00000041064,PIF1,PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae),"nuclear chromosome, telomeric region|nucleus|mitochondrion|",telomere maintenance|ATP catabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|regulation of telomere maintenance|DNA duplex unwinding|negative regulation of telomerase activity|,nucleotide binding|magnesium ion binding|DNA binding|DNA helicase activity|helicase activity|ATP binding|hydrolase activity|single-stranded DNA-dependent ATP-dependent DNA helicase activity|ATP-dependent 5'-3' DNA/RNA helicase activity|telomeric DNA binding|ATP-dependent 5'-3' DNA helicase activity|,10,0.3,2.79,10,0.2,1.21,0.3,3.73,3.73,0.419,0,0,-0.3,1.3
ENSMUSG00000020650,BCAP29,B cell receptor associated protein 29,intracellular|cell|endoplasmic reticulum|membrane|integral component of membrane|,osteoblast differentiation|transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|apoptotic process|protein transport|vesicle-mediated transport|protein localization to endoplasmic reticulum exit site|,None,10,-0.3,5.33,10,0.6,1.55,-0.3,3.72,-3.72,0.419,0,0,-1.2,1
ENSMUSG00000030376,SLC8A2,"solute carrier family 8 (sodium/calcium exchanger), member 2",mitochondrion|microtubule|plasma membrane|membrane|integral component of membrane|cell projection|neuronal cell body|dendritic spine|,sodium ion transport|sodium ion transmembrane transport|calcium ion transport into cytosol|calcium ion export from cell|calcium ion import into cell|,calcium:sodium antiporter activity|,10,-0.3,3.75,10,-0.1,0.266,-0.2,3.7,-3.7,0.421,0,0,-1.2,0.5
ENSMUSG00000071711,MPST,mercaptopyruvate sulfurtransferase,cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|cell junction|neuron projection|synapse|extracellular vesicular exosome|,hydrogen sulfide biosynthetic process|,thiosulfate sulfurtransferase activity|transferase activity|3-mercaptopyruvate sulfurtransferase activity|,10,0.3,4.46,10,-0.1,0.0141,0.2,3.68,3.68,0.422,0,0,-0.6,1.2
ENSMUSG00000021785,NGLY1,N-glycanase 1,nucleus|cytoplasm|cytoplasm|,glycoprotein catabolic process|glycoprotein catabolic process|,peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity|protein binding|hydrolase activity|metal ion binding|,10,-0.3,3.49,10,-0.2,0.393,-0.3,3.66,-3.66,0.423,0,0,-1.3,0.5
ENSMUSG00000036781,RPS27L,ribosomal protein S27-like,intracellular|nucleus|ribosome|ribonucleoprotein complex|,DNA repair|translation|activation of cysteine-type endopeptidase activity involved in apoptotic process|cellular response to DNA damage stimulus|mitotic G1 DNA damage checkpoint|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of translation|,structural constituent of ribosome|translation activator activity|cysteine-type endopeptidase activator activity involved in apoptotic process|poly(A) RNA binding|metal ion binding|,9,-0.7,2.85,9,0.6,2.8,0.5,3.63,3.63,0.425,0,0,-1.4,1.4
ENSMUSG00000022751,NIT2,"nitrilase family, member 2",cytoplasm|mitochondrion|centrosome|extracellular vesicular exosome|,oxaloacetate metabolic process|asparagine metabolic process|glutamine metabolic process|nitrogen compound metabolic process|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|omega-amidase activity|",10,0.2,1.86,10,1,2.36,0.2,3.62,3.62,0.426,0,0,-0.1,1.8
ENSMUSG00000022149,C9,complement component 9,extracellular region|membrane attack complex|cytoplasm|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|blood microparticle|,"immune system process|immune response|complement activation, alternative pathway|complement activation, classical pathway|blood coagulation|cytolysis|innate immune response|",None,10,0.8,1.62,10,0.8,2.19,0.8,3.58,3.58,0.429,0,0,-0.5,1.9
ENSMUSG00000037720,TMEM33,transmembrane protein 33,membrane|integral component of membrane|melanosome|extracellular vesicular exosome|,biological_process|,protein binding|,10,-0.2,3.19,10,-0.2,0.469,-0.2,3.47,-3.47,0.436,0,0,-1,1.4
ENSMUSG00000018599,MIEF2,mitochondrial elongation factor 2,mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,mitochondrion organization|positive regulation of protein homooligomerization|positive regulation of mitochondrial fission|positive regulation of mitochondrial fission|,molecular_function|,10,0.4,1.19,10,0.5,2.6,0.4,3.47,3.47,0.436,0,0,-0.2,1.5
ENSMUSG00000029918,MRPS33,mitochondrial ribosomal protein S33,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,9,0.5,3.83,10,1.2,0.83,0.5,3.45,3.45,0.437,0,0,-0.1,1.9
ENSMUSG00000021027,RALGAPA1,"Ral GTPase activating protein, alpha subunit 1",nucleus|cytoplasm|,"regulation of transcription, DNA-templated|positive regulation of Ran GTPase activity|activation of Ral GTPase activity|regulation of small GTPase mediated signal transduction|",GTPase activator activity|Ran GTPase activator activity|protein binding|Ral GTPase activator activity|protein heterodimerization activity|,10,0.4,0.868,10,0.4,2.79,0.4,3.44,3.44,0.438,0,0,-0.4,1.4
ENSMUSG00000033126,YBEY,ybeY metallopeptidase,nucleus|mitochondrion|,rRNA processing|biological_process|,metalloendopeptidase activity|metal ion binding|,10,0.1,0.671,10,0.4,4.21,0.4,3.4,3.4,0.441,0,0,-0.8,1.3
ENSMUSG00000025369,SMARCC2,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2",nuclear chromatin|nucleus|SWI/SNF complex|SWI/SNF complex|transcriptional repressor complex|protein complex|npBAF complex|nBAF complex|,"negative regulation of transcription from RNA polymerase II promoter|nucleosome disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|chromatin modification|regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment|ATP-dependent chromatin remodeling|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|DNA binding|chromatin binding|protein binding|nucleosomal DNA binding|,10,0.2,1.81,10,0.2,1.83,0.2,3.4,3.4,0.441,0,0,-0.6,1.3
ENSMUSG00000006567,ATP7B,"ATPase, Cu++ transporting, beta polypeptide",intracellular|cell|late endosome|Golgi apparatus|trans-Golgi network|trans-Golgi network|trans-Golgi network|plasma membrane|tight junction|membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|basolateral plasma membrane|perinuclear region of cytoplasm|,ATP catabolic process|transport|ion transport|cation transport|copper ion transport|copper ion transport|copper ion transport|cellular copper ion homeostasis|cellular zinc ion homeostasis|lactation|copper ion import|intracellular copper ion transport|metal ion transport|copper ion transmembrane transport|copper ion transmembrane transport|response to copper ion|sequestering of calcium ion|copper ion export|,nucleotide binding|copper-exporting ATPase activity|copper ion transmembrane transporter activity|copper ion binding|ATP binding|zinc ion binding|hydrolase activity|cation-transporting ATPase activity|copper-transporting ATPase activity|copper-transporting ATPase activity|metal ion binding|,10,0.2,2.64,10,0.7,1.93,0.2,3.38,3.38,0.442,0,0,-1.3,1.4
ENSMUSG00000042198,CHCHD7,coiled-coil-helix-coiled-coil-helix domain containing 7,mitochondrion|,biological_process|,molecular_function|,8,-0.4,4.49,8,0,0,-0.3,3.37,-3.37,0.443,0,0,-1.6,0.7
ENSMUSG00000048489,8430408G22RIK,RIKEN cDNA 8430408G22 gene,mitochondrion|mitochondrion|,biological_process|,molecular_function|,10,0.2,3.13,10,0.4,0.63,0.3,3.33,3.33,0.446,0,0,-0.4,1.2
ENSMUSG00000040667,NUP88,nucleoporin 88,nucleus|nuclear pore|integral component of membrane|pore complex|,transport|ion transport|protein transport|mRNA transport|,porin activity|,10,-0.6,4.14,10,-0.2,0.486,-0.5,3.32,-3.32,0.447,0,0,-1.7,1.1
ENSMUSG00000032459,MRPS22,mitochondrial ribosomal protein S22,mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,biological_process|,structural constituent of ribosome|,10,0.6,2.63,10,1.1,1.67,0.6,3.23,3.23,0.453,0,0,0,1.9
ENSMUSG00000015013,TRAPPC2L,trafficking protein particle complex 2-like,intracellular|cytoplasm|endoplasmic reticulum|Golgi apparatus|,transport|ER to Golgi vesicle-mediated transport|vesicle-mediated transport|,None,10,0.4,3.91,10,-0.3,1.01,0.3,3.23,3.23,0.453,0,0,-0.8,1.4
ENSMUSG00000045316,FAHD1,fumarylacetoacetate hydrolase domain containing 1,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|cytosol|,metabolic process|,catalytic activity|hydrolase activity|acetylpyruvate hydrolase activity|fumarylpyruvate hydrolase activity|metal ion binding|acylpyruvate hydrolase activity|,10,0.3,3.55,10,1.2,1.48,0.3,3.22,3.22,0.454,0,0,-0.3,1.9
ENSMUSG00000045665,MFSD5,major facilitator superfamily domain containing 5,plasma membrane|membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.8,0.248,10,0.8,3.13,0.8,3.2,3.2,0.456,0,0,-0.1,1.8
ENSMUSG00000068614,ACTC1,"actin, alpha, cardiac muscle 1","extracellular space|cytoplasm|cytoskeleton|actin filament|membrane|sarcomere|I band|actomyosin, actin portion|extracellular vesicular exosome|blood microparticle|",ATP catabolic process|actin filament-based movement|skeletal muscle thin filament assembly|actomyosin structure organization|actin-myosin filament sliding|negative regulation of apoptotic process|cardiac myofibril assembly|cardiac muscle tissue morphogenesis|heart contraction|cardiac muscle contraction|actin-mediated cell contraction|,nucleotide binding|ATP binding|ATPase activity|myosin binding|,10,0.5,5.33,10,-0.1,0.251,0.4,3.2,3.2,0.456,0,0,-0.9,1.4
ENSMUSG00000022296,BAALC,"brain and acute leukemia, cytoplasmic",cytoplasm|cytoplasm|membrane|,biological_process|,molecular_function|,10,-0.2,0.694,10,-0.6,4.15,-0.3,3.19,-3.19,0.456,0,0,-1.8,0.3
ENSMUSG00000045180,SHROOM2,shroom family member 2,cytoplasm|cytoskeleton|microtubule|plasma membrane|cell-cell junction|cell-cell adherens junction|tight junction|cell cortex|membrane|apical plasma membrane|apical plasma membrane|cell junction|cortical actin cytoskeleton|cortical actin cytoskeleton|filamentous actin|neuronal cell body|apical junction complex|extracellular vesicular exosome|,lens morphogenesis in camera-type eye|multicellular organismal development|brain development|eye pigment granule organization|cell migration|negative regulation of actin filament depolymerization|establishment of melanosome localization|melanosome organization|camera-type eye development|cellular pigment accumulation|ear development|apical protein localization|cell-cell junction maintenance|camera-type eye morphogenesis|,actin binding|protein binding|beta-catenin binding|protein domain specific binding|actin filament binding|,10,0.3,3.27,10,-0.2,0.381,0.3,3.19,3.19,0.456,0,0,-0.7,1.1
ENSMUSG00000034066,FARP2,"FERM, RhoGEF and pleckstrin domain protein 2",cytoplasm|cytoskeleton|extrinsic component of membrane|,cell adhesion|neuron remodeling|Rac protein signal transduction|osteoclast differentiation|actin cytoskeleton reorganization|positive regulation of Rho GTPase activity|positive regulation of Rac GTPase activity|regulation of integrin activation|regulation of Rho protein signal transduction|semaphorin-plexin signaling pathway|podosome assembly|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|cytoskeletal protein binding|Rac guanyl-nucleotide exchange factor activity|,10,0.3,4.1,10,-0.4,2.92,0.2,3.13,3.13,0.46,0,0,-1,1.1
ENSMUSG00000020464,PNPT1,polyribonucleotide nucleotidyltransferase 1,cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrial intermembrane space|mitochondrial intermembrane space|membrane|mitochondrial degradosome|,"mitochondrial RNA catabolic process|mitochondrial mRNA catabolic process|mitochondrial mRNA catabolic process|positive regulation of mitochondrial RNA catabolic process|mitochondrial RNA 5'-end processing|mitochondrial RNA 3'-end processing|RNA processing|mRNA processing|RNA catabolic process|mRNA catabolic process|transport|cellular response to oxidative stress|cellular response to interferon-beta|RNA import into mitochondrion|rRNA import into mitochondrion|regulation of cellular respiration|RNA polyadenylation|negative regulation of growth|protein homooligomerization|positive regulation of mRNA catabolic process|protein homotrimerization|mitochondrion morphogenesis|nuclear polyadenylation-dependent mRNA catabolic process|mitotic cell cycle arrest|RNA phosphodiester bond hydrolysis, exonucleolytic|mitochondrial mRNA polyadenylation|positive regulation of miRNA catabolic process|regulation of cellular senescence|",3'-5'-exoribonuclease activity|RNA binding|nuclease activity|exonuclease activity|polyribonucleotide nucleotidyltransferase activity|poly(U) RNA binding|transferase activity|nucleotidyltransferase activity|hydrolase activity|poly(G) binding|miRNA binding|poly(A) RNA binding|,10,-0.6,5.48,10,0.4,1.76,-0.6,3.13,-3.13,0.46,0,0,-1.7,0.8
ENSMUSG00000049922,SLC35C1,"solute carrier family 35, member C1",Golgi apparatus|membrane|integral component of membrane|,transport|carbohydrate transport|lipid glycosylation|negative regulation of Notch signaling pathway|transmembrane transport|,None,10,-0.8,3.33,10,-0.3,1.08,-0.7,3.12,-3.12,0.461,0,0,-1.8,0.2
ENSMUSG00000022614,LMF2,lipase maturation factor 2,endoplasmic reticulum|membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.19,10,0.3,2.28,0.2,3.12,3.12,0.461,0,0,-0.3,1.5
ENSMUSG00000040640,ERC2,ELKS/RAB6-interacting/CAST family member 2,cytoplasm|cytoskeleton|postsynaptic density|membrane|cell junction|growth cone|presynaptic membrane|neuron projection|neuronal cell body|terminal bouton|protein complex|synapse|,None,protein binding|PDZ domain binding|protein complex binding|,10,-0.4,5.46,10,0.3,1.31,-0.3,3.08,-3.08,0.464,0,0,-1.2,1.1
ENSMUSG00000063354,SLC39A4,"solute carrier family 39 (zinc transporter), member 4",endosome|plasma membrane|plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic membrane-bounded vesicle|apical plasma membrane|extracellular vesicular exosome|,transport|ion transport|zinc ion transport|cellular zinc ion homeostasis|metal ion transport|cellular response to zinc ion starvation|transmembrane transport|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|metal ion transmembrane transporter activity|,10,-0.3,2.05,10,-0.3,1.19,-0.3,3.03,-3.03,0.468,0,0,-1.3,0.9
ENSMUSG00000033940,BRK1,"BRICK1, SCAR/WAVE actin-nucleating complex subunit",cytoplasm|cytoskeleton|lamellipodium|SCAR complex|extracellular vesicular exosome|,in utero embryonic development|positive regulation of cell proliferation|positive regulation of lamellipodium assembly|Rac protein signal transduction|actin cytoskeleton organization|cell motility|protein homotrimerization|positive regulation of Arp2/3 complex-mediated actin nucleation|,protein complex binding|Rac GTPase binding|,10,-0.3,3.31,10,0.4,0.823,-0.3,3.03,-3.03,0.468,0,0,-1.3,1.1
ENSMUSG00000035900,GRAMD4,GRAM domain containing 4,cellular_component|mitochondrion|membrane|integral component of membrane|,apoptotic process|biological_process|,molecular_function|,10,0.2,1.51,10,0.4,2.41,0.2,3.02,3.02,0.469,0,0,-0.3,1.4
ENSMUSG00000026621,1-Mar,mitochondrial amidoxime reducing component 1,mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|integral component of membrane|,nitrate metabolic process|oxidation-reduction process|,catalytic activity|N-ethylmaleimide reductase activity|nitrate reductase activity|oxidoreductase activity|molybdenum ion binding|pyridoxal phosphate binding|molybdopterin cofactor binding|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0,0,10,0.5,5.74,0.5,3.01,3.01,0.47,0,0,-0.2,1.7
ENSMUSG00000053799,EXOC6,exocyst complex component 6,exocyst|,transport|exocytosis|vesicle docking involved in exocytosis|protein transport|erythrocyte differentiation|,protein binding|,10,-0.1,0.353,10,-0.7,5.05,-0.4,3.01,-3.01,0.47,0,0,-1.8,0.1
ENSMUSG00000079254,ITPRIP,"inositol 1,4,5-triphosphate receptor interacting protein",plasma membrane|membrane|membrane|,negative regulation of protein kinase activity|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|,protein kinase inhibitor activity|protein binding|,10,-0.3,4.39,10,0,0,-0.3,2.99,-2.99,0.472,0,0,-1.4,0.7
ENSMUSG00000066442,MTHFS,"5, 10-methenyltetrahydrofolate synthetase",cytoplasm|mitochondrion|,None,nucleotide binding|ATP binding|folic acid binding|ligase activity|5-formyltetrahydrofolate cyclo-ligase activity|,7,-0.5,4.11,7,0,0,-0.4,2.97,-2.97,0.473,0,0,-1.8,0.7
ENSMUSG00000031840,RAB3A,"RAB3A, member RAS oncogene family",acrosomal vesicle|cell|cytosol|plasma membrane|synaptic vesicle|synaptic vesicle|membrane|axon|terminal bouton|intracellular organelle|protein complex|,respiratory system process|GTP catabolic process|transport|exocytosis|mitochondrion organization|small GTPase mediated signal transduction|neuromuscular synaptic transmission|axonogenesis|post-embryonic development|protein transport|synaptic vesicle exocytosis|synaptic vesicle exocytosis|synaptic vesicle maturation|regulation of exocytosis|lung development|regulation of synaptic vesicle fusion to presynaptic membrane|positive regulation of ATPase activity|maintenance of presynaptic active zone structure|sensory perception of touch|response to electrical stimulus|,nucleotide binding|ATPase activator activity|GTPase activity|protein binding|GTP binding|protein C-terminus binding|GTPase binding|ATPase binding|,10,0.2,1.73,10,0.3,1.48,0.2,2.93,2.93,0.476,0,0,-0.3,1.5
ENSMUSG00000014791,ELMO3,engulfment and cell motility 3,cellular_component|cytoplasm|cytoskeleton|,phagocytosis|apoptotic process|biological_process|,protein binding|SH3 domain binding|,10,0.2,2.44,10,0.2,0.632,0.2,2.89,2.89,0.479,0,0,-0.5,1.3
ENSMUSG00000026380,TFCP2L1,transcription factor CP2-like 1,nucleus|transcription factor complex|cytoplasm|membrane|,"negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|epithelial cell maturation|transcription, DNA-templated|regulation of transcription, DNA-templated|cytoplasm organization|salivary gland development|determination of adult lifespan|positive regulation of growth|",DNA binding|protein binding|,10,0.4,2.5,9,0.3,0.568,0.4,2.88,2.88,0.48,0,0,-0.4,1.5
ENSMUSG00000057133,CHD6,chromodomain helicase DNA binding protein 6,"nucleus|nucleoplasm|DNA-directed RNA polymerase II, core complex|","ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress|","nucleotide binding|transcription cofactor binding|nucleic acid binding|DNA binding|chromatin binding|helicase activity|ATP binding|ATP-dependent helicase activity|DNA-dependent ATPase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides|",10,0.2,1.31,9,0.3,1.94,0.2,2.88,2.88,0.48,0,0,-0.6,1.5
ENSMUSG00000031775,PLLP,plasma membrane proteolipid,membrane|integral component of membrane|compact myelin|membrane raft|extracellular vesicular exosome|,transport|ion transport|,None,10,-0.6,4.47,10,0,0,-0.3,2.84,-2.84,0.483,0,0,-1.7,0.2
ENSMUSG00000056025,CLCA1,chloride channel calcium activated 1,integral component of plasma membrane|,chloride transport|chloride transmembrane transport|,intracellular calcium activated chloride channel activity|,10,0.1,0.308,10,0.6,4.47,0.3,2.84,2.84,0.483,0,0,-0.2,1.9
ENSMUSG00000035296,SGCG,"sarcoglycan, gamma (dystrophin-associated glycoprotein)",cytoplasm|cytoskeleton|plasma membrane|integral component of plasma membrane|dystroglycan complex|sarcoglycan complex|membrane|integral component of membrane|sarcolemma|,membrane organization|,protein binding|,10,0.9,5.16,10,0.2,0.076,0.3,2.82,2.82,0.485,0,0,0,1.9
ENSMUSG00000006850,TMCO6,transmembrane and coiled-coil domains 6,cellular_component|nucleus|cytoplasm|membrane|integral component of membrane|,protein import into nucleus|biological_process|,protein transporter activity|,10,0.2,1.25,10,0.6,2.75,0.4,2.82,2.82,0.485,0,0,-0.4,1.4
ENSMUSG00000020614,FAM20A,"family with sequence similarity 20, member A",extracellular region|extracellular vesicular exosome|,tooth eruption|calcium ion homeostasis|enamel mineralization|enamel mineralization|,molecular_function|,10,0.3,2.03,10,1,1.44,0.3,2.8,2.8,0.487,0,0,-0.5,1.7
ENSMUSG00000046615,ACTRT1,actin-related protein T1,cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,-0.3,3.83,10,1,2.41,-0.3,2.78,-2.78,0.489,0,0,-0.9,1.8
ENSMUSG00000009614,SARDH,sarcosine dehydrogenase,cytoplasm|mitochondrion|mitochondrion|mitochondrial matrix|,glycine catabolic process|tetrahydrofolate interconversion|oxidation-reduction process|,aminomethyltransferase activity|folic acid binding|sarcosine dehydrogenase activity|oxidoreductase activity|flavin adenine dinucleotide binding|,10,0.3,1.86,10,0.2,1.45,0.2,2.76,2.76,0.491,0,0,-0.7,1.4
ENSMUSG00000021273,FDFT1,farnesyl diphosphate farnesyl transferase 1,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|metabolic process|steroid metabolic process|cholesterol metabolic process|isoprenoid biosynthetic process|lipid biosynthetic process|biosynthetic process|sterol biosynthetic process|farnesyl diphosphate metabolic process|oxidation-reduction process|,"catalytic activity|farnesyl-diphosphate farnesyltransferase activity|oxidoreductase activity|transferase activity|transferase activity, transferring alkyl or aryl (other than methyl) groups|squalene synthase activity|",10,0.3,3.88,10,0,0,0.3,2.76,2.76,0.491,0,0,-0.4,1.4
ENSMUSG00000061126,CYP4F39,"cytochrome P450, family 4, subfamily f, polypeptide 39",cellular_component|,biological_process|oxidation-reduction process|,molecular_function|monooxygenase activity|oxidoreductase activity|metal ion binding|,10,-0.6,3.23,10,-0.2,0.713,-0.4,2.74,-2.74,0.493,0,0,-1.7,0.3
ENSMUSG00000060657,MARF1,meiosis arrest female 1,peroxisome|membrane|,double-strand break repair|meiotic nuclear division|female meiotic division|regulation of gene expression|negative regulation of phosphatase activity|cell differentiation|oogenesis|,nucleotide binding|molecular_function|nucleic acid binding|RNA binding|,10,0.2,2.5,10,0.1,0.407,0.2,2.73,2.73,0.493,0,0,-1.1,1.2
ENSMUSG00000011486,SLC25A41,"solute carrier family 25, member 41",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,-0.3,4.92,10,0.4,2.15,-0.3,2.72,-2.72,0.494,0,0,-1.2,1.2
ENSMUSG00000060924,CSMD1,CUB and Sushi multiple domains 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,1.18,10,0.5,2.66,0.3,2.7,2.7,0.496,0,0,-0.6,1.4
ENSMUSG00000057123,GJA5,"gap junction protein, alpha 5",plasma membrane|integral component of plasma membrane|gap junction|gap junction|connexon complex|intercalated disc|membrane|integral component of membrane|cell junction|cell projection|,skeletal system development|blood vessel development|renal system process involved in regulation of systemic arterial blood pressure|regulation of systemic arterial blood pressure|negative regulation of glomerular filtration|outflow tract morphogenesis|cardiac conduction system development|mitral valve development|pulmonary valve formation|ventricular septum development|atrial septum development|septum primum development|atrial ventricular junction remodeling|potassium ion transport|cell communication|cell communication by chemical coupling|cell communication by electrical coupling|positive regulation of cell communication by chemical coupling|gap junction assembly|embryonic limb morphogenesis|embryonic heart tube development|foramen ovale closure|regulation of vasodilation|negative regulation of blood pressure|positive regulation of vasoconstriction|positive regulation of vasodilation|artery morphogenesis|protein oligomerization|transmembrane transport|regulation of cardiac muscle contraction|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of atrial cardiac muscle cell membrane depolarization|regulation of atrial cardiac muscle cell membrane depolarization|regulation of ventricular cardiac muscle cell membrane depolarization|regulation of ventricular cardiac muscle cell membrane depolarization|ventricular septum morphogenesis|atrial septum morphogenesis|cardiac conduction|ventricular cardiac muscle cell action potential|atrial cardiac muscle cell action potential|SA node cell action potential|AV node cell to bundle of His cell communication by electrical coupling|cell communication by electrical coupling involved in cardiac conduction|cell communication by electrical coupling involved in cardiac conduction|cell communication involved in cardiac conduction|AV node cell to bundle of His cell communication|bundle of His cell to Purkinje myocyte communication|regulation of heart rate by cardiac conduction|regulation of renin secretion into blood stream|regulation of membrane depolarization during cardiac muscle cell action potential|vasomotion|,gap junction channel activity|gap junction hemi-channel activity|connexin binding|gap junction channel activity involved in cardiac conduction electrical coupling|gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling|,10,-0.1,0.123,10,-0.6,5.25,-0.5,2.67,-2.67,0.499,0,0,-2,0.2
ENSMUSG00000038816,CTNNAL1,"catenin (cadherin associated protein), alpha-like 1",cytoplasm|cytosol|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|,cell adhesion|Rho protein signal transduction|,structural molecule activity|cadherin binding|,10,0.4,1.42,10,0.4,1.44,0.4,2.67,2.67,0.499,0,0,-0.6,1.5
ENSMUSG00000024799,TM7SF2,transmembrane 7 superfamily member 2,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|receptor complex|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|sterol biosynthetic process|oxidation-reduction process|,"oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor|delta14-sterol reductase activity|",9,-0.1,0.336,9,0.4,5.03,0.4,2.65,2.65,0.501,0,0,-0.5,1.6
ENSMUSG00000029683,LMOD2,leiomodin 2 (cardiac),cellular_component|cytoskeleton|,biological_process|,molecular_function|actin binding|tropomyosin binding|,9,-0.5,3.6,10,-0.2,0.252,-0.4,2.63,-2.63,0.503,0,0,-1.6,0.7
ENSMUSG00000041733,COQ5,"coenzyme Q5 homolog, methyltransferase (yeast)",mitochondrion|,ubiquinone biosynthetic process|biological_process|methylation|,methyltransferase activity|transferase activity|,10,0.4,0.925,10,0.3,2.18,0.3,2.58,2.58,0.507,0,0,-0.5,1.5
ENSMUSG00000002346,SLC25A42,"solute carrier family 25, member 42",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|metabolic process|ADP transport|ATP transport|coenzyme A transmembrane transport|transmembrane transport|AMP transport|,ATP transmembrane transporter activity|ADP transmembrane transporter activity|coenzyme A transmembrane transporter activity|adenosine-diphosphatase activity|AMP transmembrane transporter activity|,10,0.2,0.0881,10,0.7,4.29,0.7,2.57,2.57,0.508,0,0,-0.6,1.7
ENSMUSG00000033576,APOL6,apolipoprotein L 6,cellular_component|,biological_process|,molecular_function|,9,-0.2,2.12,9,-0.2,0.629,-0.2,2.57,-2.57,0.508,0,0,-1.3,1.3
ENSMUSG00000026781,ACBD5,acyl-Coenzyme A binding domain containing 5,nucleus|peroxisome|peroxisome|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,transport|peroxisome degradation|,fatty-acyl-CoA binding|molecular_function|lipid binding|,10,0.1,1.29,10,0.7,2.7,0.2,2.56,2.56,0.509,0,0,-0.3,1.7
ENSMUSG00000032667,PON2,paraoxonase 2,extracellular region|nucleus|mitochondrion|lysosome|plasma membrane|membrane|intracellular membrane-bounded organelle|,aromatic compound catabolic process|,arylesterase activity|hydrolase activity|identical protein binding|metal ion binding|,10,0.2,1.49,10,0.3,1.38,0.3,2.55,2.55,0.51,0,0,-0.5,1.4
ENSMUSG00000039988,ANKRD13C,ankyrin repeat domain 13c,endoplasmic reticulum|endoplasmic reticulum|membrane|perinuclear region of cytoplasm|,protein retention in ER lumen|regulation of receptor biosynthetic process|regulation of anoikis|,receptor binding|,10,0.2,2.53,10,0.1,0.308,0.2,2.53,2.53,0.512,0,0,-0.8,1.2
ENSMUSG00000089774,SLC5A3,"solute carrier family 5 (inositol transporters), member 3",membrane|integral component of membrane|,inositol metabolic process|transport|ion transport|sodium ion transport|peripheral nervous system development|myo-inositol transport|regulation of respiratory gaseous exchange|transmembrane transport|,transporter activity|symporter activity|,10,-0.3,2.1,10,-0.2,0.618,-0.2,2.51,-2.51,0.514,0,0,-1.5,0.7
ENSMUSG00000035392,DENND1A,DENN/MADD domain containing 1A,plasma membrane|membrane|cell junction|clathrin-coated vesicle|clathrin-coated vesicle|dendrite|clathrin-coated vesicle membrane|cytoplasmic vesicle|neuronal cell body|synapse|,transport|endocytosis|protein transport|regulation of Rab protein signal transduction|positive regulation of Rab GTPase activity|synaptic vesicle endocytosis|,guanyl-nucleotide exchange factor activity|protein binding|Rab guanyl-nucleotide exchange factor activity|SH3 domain binding|,10,0.3,2.63,10,0.1,0.265,0.2,2.48,2.48,0.517,0,0,-0.8,1.3
ENSMUSG00000042613,PBXIP1,pre B cell leukemia transcription factor interacting protein 1,nucleus|cytoplasm|cytoskeleton|microtubule|,biological_process|,molecular_function|,10,0.3,2.07,10,0.1,0.584,0.2,2.45,2.45,0.52,0,0,-0.7,1.4
ENSMUSG00000044221,GRSF1,G-rich RNA sequence binding factor 1,cytoplasm|mitochondrion|mitochondrion|mitochondrial nucleoid|,mRNA processing|tRNA processing|anterior/posterior pattern specification|morphogenesis of embryonic epithelium|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.1,0.262,10,-0.6,3.76,-0.3,2.43,-2.43,0.522,0,0,-1.9,0.2
ENSMUSG00000029376,MTHFD2L,methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like,mitochondrion|mitochondrial inner membrane|mitochondrial matrix|membrane|,histidine biosynthetic process|purine nucleotide biosynthetic process|one-carbon metabolic process|metabolic process|cellular amino acid biosynthetic process|methionine biosynthetic process|10-formyltetrahydrofolate metabolic process|folic acid-containing compound biosynthetic process|tetrahydrofolate interconversion|oxidation-reduction process|,catalytic activity|methenyltetrahydrofolate cyclohydrolase activity|methylenetetrahydrofolate dehydrogenase (NAD+) activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|oxidoreductase activity|hydrolase activity|,10,-0.2,3.66,10,0.5,1.75,-0.2,2.42,-2.42,0.523,0,0,-1.1,1.5
ENSMUSG00000079036,ALKBH1,"alkB, alkylation repair homolog 1 (E. coli)",nucleus|nuclear euchromatin|mitochondrion|,"DNA catabolic process, endonucleolytic|in utero embryonic development|neuron migration|placenta development|DNA repair|DNA dealkylation involved in DNA repair|cellular response to DNA damage stimulus|metabolic process|regulation of gene expression|cell differentiation|neuron projection development|RNA repair|negative regulation of neuron apoptotic process|developmental growth|positive chemotaxis|oxidation-reduction process|oxidative demethylation|DNA demethylation|","catalytic activity|DNA-(apurinic or apyrimidinic site) lyase activity|protein binding|ferrous iron binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|lyase activity|chemoattractant activity|metal ion binding|dioxygenase activity|methylcytosine dioxygenase activity|",10,-0.2,2.36,10,0.3,0.434,-0.2,2.39,-2.39,0.526,0,0,-1.4,0.9
ENSMUSG00000024862,KLC2,kinesin light chain 2,intracellular|cell|cytoplasm|cytosol|cytoskeleton|kinesin complex|microtubule|membrane|ciliary rootlet|ciliary rootlet|neuron projection|protein complex|,microtubule-based movement|axon cargo transport|,microtubule motor activity|protein binding|kinesin binding|,10,0.2,1.48,10,0.3,1.38,0.2,2.39,2.39,0.526,0,0,-0.6,1.5
ENSMUSG00000029486,MRPL1,mitochondrial ribosomal protein L1,nucleus|mitochondrion|mitochondrion|mitochondrial large ribosomal subunit|ribosome|large ribosomal subunit|ribonucleoprotein complex|,translation|,RNA binding|structural constituent of ribosome|poly(A) RNA binding|,10,0.1,0.563,10,-0.4,2.26,-0.3,2.38,-2.38,0.527,0,0,-1.5,0.7
ENSMUSG00000029475,KDM2B,lysine (K)-specific demethylase 2B,nucleus|PcG protein complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|chromatin modification|histone demethylation|midbrain-hindbrain boundary morphogenesis|fourth ventricle development|lateral ventricle development|third ventricle development|initiation of neural tube closure|forebrain development|midbrain development|hindbrain development|histone H2A monoubiquitination|negative regulation of neuron apoptotic process|embryonic camera-type eye morphogenesis|oxidation-reduction process|negative regulation of neural precursor cell proliferation|",DNA binding|RNA binding|protein binding|zinc ion binding|oxidoreductase activity|rRNA binding|histone demethylase activity|metal ion binding|dioxygenase activity|histone demethylase activity (H3-K36 specific)|,10,0.1,1.15,10,0.5,2.6,0.2,2.35,2.35,0.53,0,0,-0.3,1.5
ENSMUSG00000030872,GGA2,"golgi associated, gamma adaptin ear containing, ARF binding protein 2",intracellular|endosome|Golgi apparatus|trans-Golgi network|membrane|clathrin adaptor complex|clathrin-coated vesicle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,protein binding|ADP-ribosylation factor binding|,10,-0.5,0.393,10,0.4,2.41,0.4,2.34,2.34,0.531,0,0,-0.8,1.7
ENSMUSG00000069874,IRGM2,immunity-related GTPase family M member 2,Golgi apparatus|symbiont-containing vacuole|,GTP catabolic process|response to interferon-gamma|response to interferon-gamma|defense response to bacterium|defense response to protozoan|,GTPase activity|,10,0.2,2.42,10,0.1,0.14,0.2,2.33,2.33,0.532,0,0,-1,1.4
ENSMUSG00000026991,PKP4,plakophilin 4,spindle pole|cytoplasm|cytoskeleton|plasma membrane|cell-cell junction|cytoplasmic side of plasma membrane|membrane|cell junction|desmosome|midbody|midbody|cell-cell contact zone|perinuclear region of cytoplasm|spindle midzone|mitotic spindle|,cell-cell junction assembly|cell adhesion|positive regulation of gene expression|single organismal cell-cell adhesion|positive regulation of Rho GTPase activity|positive regulation of cytokinesis|,None,10,0.4,4.78,10,-0.2,0.617,0.4,2.33,2.33,0.532,0,0,-0.8,1.5
ENSMUSG00000062127,CTTNBP2NL,CTTNBP2 N-terminal like,cytoplasm|cytoskeleton|actin cytoskeleton|,protein dephosphorylation|protein dephosphorylation|negative regulation of transporter activity|negative regulation of transmembrane transport|,protein phosphatase 2A binding|,10,-0.2,0.687,10,0.6,4.91,0.6,2.32,2.32,0.533,0,0,-0.6,1.7
ENSMUSG00000063415,CYP26B1,"cytochrome P450, family 26, subfamily b, polypeptide 1",cytoplasm|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,cell fate determination|male meiosis|spermatogenesis|proximal/distal pattern formation|positive regulation of gene expression|embryonic limb morphogenesis|retinoic acid catabolic process|retinoic acid catabolic process|retinoic acid metabolic process|tongue morphogenesis|retinoic acid receptor signaling pathway|retinoic acid receptor signaling pathway|negative regulation of retinoic acid receptor signaling pathway|oxidation-reduction process|bone morphogenesis|establishment of skin barrier|cornification|positive regulation of tongue muscle cell differentiation|,"retinoic acid binding|monooxygenase activity|iron ion binding|retinoic acid 4-hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|fluorene oxygenase activity|mono-butyltin dioxygenase activity|tri-n-butyltin dioxygenase activity|di-n-butyltin dioxygenase activity|methylsilanetriol hydroxylase activity|methyl tertiary butyl ether 3-monooxygenase activity|4-nitrocatechol 4-monooxygenase activity|4-chlorophenoxyacetate monooxygenase activity|tert-butanol 2-monooxygenase activity|alpha-pinene monooxygenase activity|dimethylsilanediol hydroxylase activity|ammonia monooxygenase activity|hydroxymethylsilanetriol oxidase activity|2-hydroxyisobutyrate 3-monooxygenase activity|alpha-pinene dehydrogenase activity|heme binding|bisphenol A hydroxylase B activity|2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity|9-fluorenone-3,4-dioxygenase activity|anthracene 9,10-dioxygenase activity|2-(methylthio)benzothiazole monooxygenase activity|2-hydroxybenzothiazole monooxygenase activity|benzothiazole monooxygenase activity|2,6-dihydroxybenzothiazole monooxygenase activity|pinacolone 5-monooxygenase activity|thioacetamide S-oxygenase activity|thioacetamide S-oxide S-oxygenase activity|endosulfan monooxygenase I activity|N-nitrodimethylamine hydroxylase activity|4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity|endosulfan ether monooxygenase activity|pyrene 4,5-monooxygenase activity|pyrene 1,2-monooxygenase activity|1-hydroxypyrene 6,7-monooxygenase activity|1-hydroxypyrene 7,8-monooxygenase activity|phenylboronic acid monooxygenase activity|spheroidene monooxygenase activity|metal ion binding|",10,-0.7,1.67,10,-0.5,0.83,-0.6,2.27,-2.27,0.538,0,0,-1.9,0.2
ENSMUSG00000040483,XAF1,XIAP associated factor 1,nucleus|cytoplasm|mitochondrion|,apoptotic process|negative regulation of protein complex assembly|response to interferon-beta|,metal ion binding|,10,0.4,3.62,10,0.1,0.0821,0.2,2.27,2.27,0.538,0,0,-0.4,1.6
ENSMUSG00000027782,KPNA4,karyopherin (importin) alpha 4,intracellular|cell|nucleus|cytoplasm|extracellular vesicular exosome|,protein import into nucleus|transport|protein transport|,protein binding|protein transporter activity|,10,0.1,0.542,10,1,2.79,0.2,2.23,2.23,0.542,0,0,-0.2,2
ENSMUSG00000061894,ZSCAN20,zinc finger and SCAN domains 20,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|chromatin binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.2,1.32,10,0.2,1.08,0.2,2.23,2.23,0.542,0,0,-0.6,1.5
ENSMUSG00000030245,GOLT1B,golgi transport 1 homolog B (S. cerevisiae),endoplasmic reticulum|Golgi apparatus|membrane|membrane|integral component of membrane|,transport|signal transduction|protein transport|vesicle-mediated transport|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|,10,-0.8,3.32,10,1.2,3.67,-0.8,2.22,-2.22,0.543,0,0,-1.7,1.8
ENSMUSG00000034792,GNA15,"guanine nucleotide binding protein, alpha 15",heterotrimeric G-protein complex|membrane|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration|phospholipase C-activating dopamine receptor signaling pathway|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|signal transducer activity|signal transducer activity|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,-0.4,3.43,10,0,0,-0.3,2.19,-2.19,0.547,0,0,-1.6,0.7
ENSMUSG00000040127,SDR9C7,"4short chain dehydrogenase/reductase family 9C, member 7",nucleolus|cytoplasm|,metabolic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|retinol dehydrogenase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.6,1.27,10,0.2,1.38,0.2,2.19,2.19,0.547,0,0,-0.7,1.8
ENSMUSG00000034903,COBLL1,Cobl-like 1,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,1.84,10,0.2,0.524,0.2,2.18,2.18,0.548,0,0,-1.2,1
ENSMUSG00000049521,CDC42EP1,CDC42 effector protein (Rho GTPase binding) 1,cytoplasm|cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|,Rho protein signal transduction|regulation of cell shape|positive regulation of pseudopodium assembly|,protein binding|,10,0.1,0.109,10,0.6,4.64,0.5,2.18,2.18,0.548,0,0,-0.2,1.9
ENSMUSG00000000416,CTTNBP2,cortactin binding protein 2,cytoplasm|synaptic vesicle|actin cytoskeleton|cell projection|,actin cytoskeleton organization|,cytoskeletal regulatory protein binding|SH3 domain binding|,10,-0.3,3.23,10,0,0,-0.2,2.16,-2.16,0.55,0,0,-1.3,1
ENSMUSG00000029707,FSCN3,"fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)",cytoplasm|cytoskeleton|,spermatid development|,"actin binding|protein binding, bridging|actin filament binding|",10,0.6,3.45,10,0,0,0.2,2.14,2.14,0.552,0,0,-0.4,2
ENSMUSG00000090935,SYNJ2BP,synaptojanin 2 binding protein,intracellular|cell|mitochondrion|mitochondrial outer membrane|integral component of mitochondrial outer membrane|,protein targeting|cytoplasm organization|Rho protein signal transduction|regulation of endocytosis|intracellular distribution of mitochondria|,protein C-terminus binding|,5,-0.1,0.114,5,0.6,4.24,0.6,2.14,2.14,0.552,0,0,-0.9,2
ENSMUSG00000036131,FRMD7,FERM domain containing 7,extracellular space|cytoskeleton|growth cone|cell projection|neuron projection|neuronal cell body|,nervous system development|regulation of neuron projection development|,molecular_function|,10,-0.3,2.44,10,-0.1,0.152,-0.3,2.13,-2.13,0.553,0,0,-1.6,0.6
ENSMUSG00000043463,RAB9B,"RAB9B, member RAS oncogene family",plasma membrane|membrane|cytoplasmic vesicle|phagocytic vesicle|,transport|small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTP binding|GDP binding|,9,0.1,0.682,9,0.2,1.83,0.2,2.1,2.1,0.556,0,0,-0.8,1.6
ENSMUSG00000020949,FKBP3,FK506 binding protein 3,nucleus|endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|protein binding|FK506 binding|isomerase activity|poly(A) RNA binding|,9,-0.3,2.26,9,-0.1,0.391,-0.3,2.1,-2.1,0.556,0,0,-1.5,0.9
ENSMUSG00000034484,SNX2,sorting nexin 2,cytoplasm|endosome|endosome membrane|membrane|cytoplasmic membrane-bounded vesicle|retromer complex|intracellular membrane-bounded organelle|extracellular vesicular exosome|,transport|intracellular protein transport|endocytosis|protein transport|,lipid binding|phosphatidylinositol binding|,10,-0.3,1.5,10,-0.2,0.871,-0.2,2.09,-2.09,0.557,0,0,-1.6,0.5
ENSMUSG00000030138,BMS1,"BMS1 homolog, ribosome assembly protein (yeast)",nucleus|nucleolus|,biological_process|,nucleotide binding|GTP binding|poly(A) RNA binding|,9,-0.3,3.44,9,0.6,0.73,0.5,2.09,2.09,0.557,0,0,-0.9,1.6
ENSMUSG00000019883,ECHDC1,enoyl Coenzyme A hydratase domain containing 1,cytoplasm|cytosol|extracellular vesicular exosome|,metabolic process|,catalytic activity|methylmalonyl-CoA decarboxylase activity|lyase activity|carboxy-lyase activity|,10,-0.2,2.38,10,-0.1,0.0706,-0.2,2.08,-2.08,0.558,0,0,-1.5,0.7
ENSMUSG00000042348,ARL15,ADP-ribosylation factor-like 15,intracellular|extracellular vesicular exosome|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0,0,10,0.3,2.3,0.3,2.07,2.07,0.559,0,0,-0.8,1.5
ENSMUSG00000034463,SCARA3,"scavenger receptor class A, member 3",cellular_component|collagen trimer|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.412,10,0.7,3.26,0.2,2.07,2.07,0.559,0,0,-0.4,1.8
ENSMUSG00000041479,SYT15,synaptotagmin XV,membrane|integral component of membrane|extrinsic component of membrane|,None,None,9,0,0,9,-0.5,3.67,-0.4,2.06,-2.06,0.561,0,0,-1.9,0.4
ENSMUSG00000053025,SV2B,synaptic vesicle glycoprotein 2 b,synaptic vesicle|synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,transport|neurotransmitter transport|synaptic transmission|transmembrane transport|,transporter activity|transmembrane transporter activity|,10,-0.2,0.547,10,-0.5,1.85,-0.3,2.04,-2.04,0.563,0,0,-1.8,0.5
ENSMUSG00000022742,CPOX,coproporphyrinogen oxidase,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|,ATP catabolic process|porphyrin-containing compound biosynthetic process|protoporphyrinogen IX biosynthetic process|heme biosynthetic process|heme biosynthetic process|potassium ion transport|sodium ion transport|sodium ion transmembrane transport|oxidation-reduction process|potassium ion transmembrane transport|,coproporphyrinogen oxidase activity|coproporphyrinogen oxidase activity|structural constituent of eye lens|sodium:potassium-exchanging ATPase activity|oxidoreductase activity|identical protein binding|protein homodimerization activity|,10,-0.2,2.02,10,-0.1,0.336,-0.2,2.01,-2.01,0.566,0,0,-1.4,1
ENSMUSG00000026303,MLPH,melanophilin,stress fiber|intracellular|cell|microtubule organizing center|actin cytoskeleton|cortical actin cytoskeleton|microtubule plus-end|melanosome|melanosome|,protein targeting|intracellular protein transport|melanocyte differentiation|melanosome localization|pigmentation|,actin binding|protein binding|myosin binding|Rab GTPase binding|myosin V binding|metal ion binding|microtubule plus-end binding|,10,0.2,1.38,10,-0.6,4.86,-0.5,1.99,-1.99,0.569,0,0,-1.9,0.5
ENSMUSG00000037747,PHYHIPL,phytanoyl-CoA hydroxylase interacting protein-like,cytoplasm|mitochondrion|,biological_process|,molecular_function|,10,-0.5,1.4,10,-0.2,1.07,-0.3,1.97,-1.97,0.571,0,0,-1.6,1
ENSMUSG00000047945,MARCKSL1,MARCKS-like 1,cytoplasm|plasma membrane|membrane|extracellular vesicular exosome|,positive regulation of cell proliferation|,actin binding|calmodulin binding|,10,-0.2,0.824,10,0.4,4.16,0.4,1.95,1.95,0.573,0,0,-1.1,1.4
ENSMUSG00000026499,ACBD3,acyl-Coenzyme A binding domain containing 3,Golgi membrane|mitochondrion|Golgi apparatus|membrane|membrane|integral component of membrane|,lipid metabolic process|steroid biosynthetic process|transport|,fatty-acyl-CoA binding|,10,0.2,1.29,10,0.4,1.2,0.2,1.95,1.95,0.573,0,0,-0.8,1.5
ENSMUSG00000001313,RND2,Rho family GTPase 2,intracellular|early endosome|membrane|cytoplasmic vesicle|,small GTPase mediated signal transduction|positive regulation of collateral sprouting|,nucleotide binding|protein binding|GTP binding|protein N-terminus binding|,10,0.3,1.67,10,0.3,0.424,0.3,1.95,1.95,0.573,0,0,-0.7,1.6
ENSMUSG00000009646,PLA2G12B,"phospholipase A2, group XIIB",cellular_component|extracellular region|,lipid catabolic process|cholesterol homeostasis|triglyceride homeostasis|,molecular_function|phospholipase A2 activity|calcium ion binding|hydrolase activity|metal ion binding|,10,0.2,0.986,10,0.5,1.7,0.3,1.95,1.95,0.573,0,0,-1.2,1.5
ENSMUSG00000052551,ADARB2,"adenosine deaminase, RNA-specific, B2",nucleus|,RNA processing|mRNA processing|,RNA binding|adenosine deaminase activity|hydrolase activity|poly(A) RNA binding|metal ion binding|,10,0.3,3.56,10,0,0,0.2,1.92,1.92,0.576,0,0,-0.7,1.5
ENSMUSG00000015759,CNIH1,cornichon homolog 1 (Drosophila),cellular_component|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,transport|biological_process|vesicle-mediated transport|intracellular signal transduction|,molecular_function|,10,-0.2,3.51,10,0.3,3.67,-0.2,1.92,-1.92,0.576,0,0,-0.5,1.9
ENSMUSG00000026154,1110058L19RIK,RIKEN cDNA 1110058L19 gene,extracellular region|mitochondrion|,innate immune response|,molecular_function|,9,0.1,1.05,9,0.3,1.16,0.2,1.91,1.91,0.577,0,0,-0.6,1.6
ENSMUSG00000011658,FUZ,fuzzy homolog (Drosophila),cytoplasm|cytoskeleton|extracellular vesicular exosome|,establishment of planar polarity|neural tube closure|neural tube closure|hair follicle development|transport|multicellular organismal development|negative regulation of cell proliferation|regulation of smoothened signaling pathway|embryonic body morphogenesis|protein transport|spinal cord dorsal/ventral patterning|cell projection organization|negative regulation of cell migration|nonmotile primary cilium assembly|nonmotile primary cilium assembly|cilium assembly|positive regulation of cilium assembly|positive regulation of cilium assembly|embryonic skeletal system morphogenesis|negative regulation of canonical Wnt signaling pathway|negative regulation of neural crest formation|negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation|,None,10,0.3,1.74,10,-1.1,1.38,0.3,1.9,1.9,0.578,0,0,-2,0.9
ENSMUSG00000020783,1200014J11RIK,RIKEN cDNA 1200014J11 gene,cellular_component|,biological_process|,nucleotide binding|poly(A) RNA binding|,10,-0.2,2.44,10,0,0,-0.2,1.89,-1.89,0.58,0,0,-1.4,1
ENSMUSG00000025854,FAM20C,"family with sequence similarity 20, member C",extracellular region|extracellular space|extracellular space|Golgi apparatus|extracellular vesicular exosome|,skeletal system development|protein phosphorylation|phosphorylation|positive regulation of bone mineralization|biomineral tissue development|osteoclast maturation|regulation of fibroblast growth factor receptor signaling pathway|positive regulation of osteoblast differentiation|regulation of phosphorus metabolic process|enamel mineralization|odontoblast differentiation|dentinogenesis|,protein serine/threonine kinase activity|calcium ion binding|kinase activity|transferase activity|metal ion binding|,10,-0.1,0.979,10,-0.3,1.13,-0.2,1.87,-1.87,0.582,0,0,-1.4,1
ENSMUSG00000041112,ELMO1,engulfment and cell motility 1,cytoplasm|cytoplasm|cytoskeleton|plasma membrane|plasma membrane|membrane|membrane|,"phagocytosis|phagocytosis, engulfment|phagocytosis, engulfment|apoptotic process|cellular component movement|cellular component movement|Rac protein signal transduction|Rac protein signal transduction|actin filament-based process|actin cytoskeleton organization|actin cytoskeleton organization|",protein binding|SH3 domain binding|,10,0.1,0.332,10,-0.4,3.08,-0.3,1.82,-1.82,0.588,0,0,-1.5,1.1
ENSMUSG00000029101,RGS12,regulator of G-protein signaling 12,nucleus|nucleolus|cytoplasm|cytoplasm|cytosol|plasma membrane|plasma membrane|neuronal cell body|protein complex|apical dendrite|,signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|positive regulation of GTPase activity|regulation of catalytic activity|,G-protein alpha-subunit binding|receptor signaling protein activity|GTPase activator activity|GTPase activator activity|protein binding|GTPase regulator activity|,10,-0.2,1.21,10,-0.7,1.76,-0.2,1.82,-1.82,0.588,0,0,-1.9,0.6
ENSMUSG00000044041,KRT13,keratin 13,nucleus|intermediate filament|keratin filament|intermediate filament cytoskeleton|extracellular vesicular exosome|,cytoskeleton organization|,structural molecule activity|protein binding|,10,0.2,2.43,10,-0.1,0.0931,0.2,1.81,1.81,0.59,0,0,-1.1,1.3
ENSMUSG00000049907,RASL11B,"RAS-like, family 11, member B",membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|,nucleotide binding|GTP binding|,10,0.5,1.3,10,0.4,0.747,0.5,1.79,1.79,0.592,0,0,-0.3,1.8
ENSMUSG00000036790,SLITRK2,"SLIT and NTRK-like family, member 2",membrane|integral component of membrane|,axonogenesis|,molecular_function|,10,0,0,10,1.1,2.86,0.5,1.79,1.79,0.592,0,0,-0.1,2
ENSMUSG00000020396,NEFH,"neurofilament, heavy polypeptide",cytoplasm|mitochondrion|intermediate filament|neurofilament|axon|neurofibrillary tangle|,microtubule cytoskeleton organization|neurofilament bundle assembly|intermediate filament cytoskeleton organization|intermediate filament bundle assembly|intermediate filament bundle assembly|peripheral nervous system neuron axonogenesis|neurofilament cytoskeleton organization|neurofilament cytoskeleton organization|axon development|axon development|regulation of organelle transport along microtubule|,"structural molecule activity|structural constituent of cytoskeleton|protein kinase binding|protein binding, bridging|nutrient reservoir activity|",10,-0.4,2.82,10,0.1,0.0275,-0.3,1.79,-1.79,0.592,0,0,-1.5,0.7
ENSMUSG00000036894,RAP2B,"RAP2B, member of RAS oncogene family",endosome|cytosol|plasma membrane|membrane|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|negative regulation of cell migration|positive regulation of protein autophosphorylation|Rap protein signal transduction|regulation of protein tyrosine kinase activity|,nucleotide binding|GTP binding|GDP binding|protein domain specific binding|,10,0.2,1.88,10,0.2,0.0346,0.2,1.79,1.79,0.592,0,0,-0.7,1.7
ENSMUSG00000020067,MYPN,myopalladin,nucleus|cytoplasm|Z disc|Z disc|Z disc|I band|I band|,sarcomere organization|,actin binding|cytoskeletal protein binding|SH3 domain binding|muscle alpha-actinin binding|,10,-0.2,1.81,10,0.3,0.666,-0.2,1.78,-1.78,0.593,0,0,-1.3,1.3
ENSMUSG00000020354,SGCD,"sarcoglycan, delta (dystrophin-associated glycoprotein)",cytoplasm|cytoskeleton|plasma membrane|integral component of plasma membrane|dystrophin-associated glycoprotein complex|dystroglycan complex|sarcoglycan complex|membrane|integral component of membrane|sarcolemma|,membrane organization|,protein binding|,10,-0.1,1.14,10,-0.2,0.825,-0.2,1.78,-1.78,0.593,0,0,-1.6,0.7
ENSMUSG00000070493,CHCHD2,coiled-coil-helix-coiled-coil-helix domain containing 2,mitochondrion|mitochondrion|,biological_process|,molecular_function|,10,-0.2,1.31,10,-0.2,0.6,-0.2,1.77,-1.77,0.595,0,0,-1.5,0.9
ENSMUSG00000031958,LDHD,lactate dehydrogenase D,mitochondrion|mitochondrial inner membrane|,ATP biosynthetic process|oxidation-reduction process|,"catalytic activity|D-lactate dehydrogenase (cytochrome) activity|protein binding|D-lactate dehydrogenase activity|UDP-N-acetylmuramate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|flavin adenine dinucleotide binding|",10,0.1,0.238,10,-0.4,4.34,-0.4,1.77,-1.77,0.595,0,0,-1.6,0.6
ENSMUSG00000029695,AASS,aminoadipate-semialdehyde synthase,mitochondrion|mitochondrion|intracellular membrane-bounded organelle|,generation of precursor metabolites and energy|metabolic process|L-lysine catabolic process|oxidation-reduction process|,"catalytic activity|oxidoreductase activity|saccharopine dehydrogenase (NADP+, L-lysine-forming) activity|saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity|saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity|",10,0.2,0.786,10,0.2,1.13,0.2,1.77,1.77,0.595,0,0,-0.8,1.6
ENSMUSG00000034219,14-Sep,septin 14,cellular_component|cytoplasm|cytoskeleton|septin complex|,cell cycle|biological_process|cell division|,nucleotide binding|molecular_function|GTP binding|,10,-0.8,4.63,10,0.1,0.324,-0.8,1.77,-1.77,0.595,0,0,-2,0.5
ENSMUSG00000027481,BPIFB2,"BPI fold containing family B, member 2",cellular_component|extracellular region|,biological_process|,lipid binding|,10,-0.1,0.272,10,0.4,4.31,0.4,1.76,1.76,0.596,0,0,-0.6,1.6
ENSMUSG00000091803,COX16,cytochrome c oxidase assembly protein 16,mitochondrion|membrane|integral component of membrane|mitochondrial membrane|,biological_process|,molecular_function|,6,0.3,1.42,6,0.2,0.62,0.3,1.75,1.75,0.597,0,0,-0.9,2
ENSMUSG00000037148,ARHGAP10,Rho GTPase activating protein 10,intracellular|cytoplasm|cytosol|plasma membrane|membrane|,cytoskeleton organization|signal transduction|positive regulation of Rho GTPase activity|negative regulation of apoptotic process|,GTPase activator activity|Rho GTPase activator activity|protein binding|,10,0.3,2.28,10,0,0,0.3,1.74,1.74,0.598,0,0,-0.7,1.6
ENSMUSG00000056148,RDH9,retinol dehydrogenase 9,cellular_component|,9-cis-retinoic acid biosynthetic process|oxidation-reduction process|,retinol dehydrogenase activity|,3,0,0,3,-0.6,3.27,-0.5,1.74,-1.74,0.598,0,0,-1.9,1.8
ENSMUSG00000050174,NUDT6,nudix (nucleoside diphosphate linked moiety X)-type motif 6,cellular_component|nucleus|cytoplasm|mitochondrion|,biological_process|,"thiamine-pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|",10,0,0,10,0.8,2.96,0.7,1.74,1.74,0.598,0,0,-0.3,1.9
ENSMUSG00000042505,ACN9,ACN9 homolog (S. cerevisiae),mitochondrion|mitochondrial intermembrane space|,biological_process|,molecular_function|,10,-0.5,4.1,10,0.5,0.171,-0.5,1.74,-1.74,0.598,0,0,-1.7,1.1
ENSMUSG00000037636,SLC25A43,"solute carrier family 25, member 43",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0.3,2.16,10,0.1,0.295,0.3,1.73,1.73,0.6,0,0,-0.6,1.7
ENSMUSG00000030968,PDILT,"protein disulfide isomerase-like, testis expressed",endoplasmic reticulum|,protein folding|multicellular organismal development|spermatogenesis|spermatid development|cell migration|cell differentiation|cell redox homeostasis|,protein disulfide isomerase activity|protein binding|isomerase activity|peptidyl-proline 4-dioxygenase activity|,10,0.2,2.09,10,0,0,0.2,1.72,1.72,0.601,0,0,-1,1.6
ENSMUSG00000041912,TDRKH,tudor and KH domain containing protein,cytoplasm|mitochondrion|pi-body|piP-body|,male meiosis|spermatogenesis|fertilization|cell differentiation|gene silencing by RNA|piRNA metabolic process|DNA methylation involved in gamete generation|,RNA binding|protein binding|,10,-0.4,1.73,10,-0.2,0.223,-0.4,1.71,-1.71,0.602,0,0,-1.8,0.5
ENSMUSG00000068270,SHROOM4,shroom family member 4,stress fiber|cytoplasm|cytoskeleton|cytoplasmic side of plasma membrane|cytoplasmic side of plasma membrane|basal plasma membrane|actin cytoskeleton|apical plasma membrane|myosin II complex|cortical actin cytoskeleton|filamentous actin|,actin filament organization|multicellular organismal development|brain development|cognition|,actin binding|actin filament binding|,10,-0.2,2.27,10,0,0,-0.2,1.69,-1.69,0.604,0,0,-1.5,0.8
ENSMUSG00000026482,RGL1,"ral guanine nucleotide dissociation stimulator,-like 1",intracellular|,signal transduction|small GTPase mediated signal transduction|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|,10,0.4,1.34,10,-0.8,1.91,-0.6,1.67,-1.67,0.607,0,0,-2,0.8
ENSMUSG00000042761,MRAP2,melanocortin 2 receptor accessory protein 2,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,energy reserve metabolic process|feeding behavior|positive regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|protein localization to cell surface|energy homeostasis|,corticotropin hormone receptor binding|type 3 melanocortin receptor binding|type 4 melanocortin receptor binding|type 4 melanocortin receptor binding|type 5 melanocortin receptor binding|type 1 melanocortin receptor binding|,10,0.1,0.0952,10,0.5,1.93,0.4,1.65,1.65,0.61,0,0,-0.3,1.7
ENSMUSG00000023055,CALCOCO1,calcium binding and coiled coil domain 1,nuclear chromatin|nucleus|nucleus|cytoplasm|intracellular membrane-bounded organelle|,"transcription, DNA-templated|signal transduction|Wnt signaling pathway|intracellular steroid hormone receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of RNA biosynthetic process|",chromatin binding|transcription cofactor activity|transcription coactivator activity|transcription coactivator activity|protein binding|beta-catenin binding|protein C-terminus binding|ligand-dependent nuclear receptor transcription coactivator activity|sequence-specific DNA binding|transcription regulatory region DNA binding|armadillo repeat domain binding|,10,-0.2,2.02,10,0,0,-0.1,1.64,-1.64,0.611,0,0,-1.6,0.9
ENSMUSG00000030759,FAR1,fatty acyl CoA reductase 1,peroxisome|peroxisome|peroxisomal membrane|membrane|integral component of membrane|,lipid metabolic process|ether lipid biosynthetic process|wax biosynthetic process|long-chain fatty-acyl-CoA metabolic process|glycerophospholipid biosynthetic process|oxidation-reduction process|,oxidoreductase activity|long-chain-fatty-acyl-CoA reductase activity|fatty-acyl-CoA reductase (alcohol-forming) activity|,10,-0.3,0.8,10,-0.2,1.03,-0.2,1.64,-1.64,0.611,0,0,-1.5,1.1
ENSMUSG00000035775,KRT20,keratin 20,cytoplasm|intermediate filament|,apoptotic process|cellular response to stress|intermediate filament organization|intermediate filament organization|regulation of protein secretion|,structural molecule activity|protein binding|,10,0.2,1.93,10,0.1,0.00224,0.2,1.64,1.64,0.611,0,0,-0.8,1.5
ENSMUSG00000023010,TMBIM6,transmembrane BAX inhibitor motif containing 6,intracellular|endoplasmic reticulum|membrane|membrane|integral component of membrane|,apoptotic process|response to unfolded protein|endoplasmic reticulum calcium ion homeostasis|negative regulation of apoptotic process|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,None,10,-0.1,0.852,10,-0.3,1.43,-0.2,1.63,-1.63,0.612,0,0,-1.7,0.5
ENSMUSG00000035031,C8A,"complement component 8, alpha polypeptide",extracellular region|membrane attack complex|extracellular space|plasma membrane|membrane|integral component of membrane|blood microparticle|,"immune system process|immune response|complement activation|complement activation, alternative pathway|complement activation, classical pathway|cytolysis|innate immune response|",complement binding|protein complex binding|,10,0,0,10,-0.7,3.8,-0.4,1.63,-1.63,0.612,0,0,-2,0.3
ENSMUSG00000041658,RRAGB,Ras-related GTP binding B,nucleus|cytoplasm|lysosome|lysosomal membrane|Golgi apparatus|intracellular membrane-bounded organelle|,positive regulation of TOR signaling|cellular protein localization|cellular response to amino acid stimulus|,nucleotide binding|GTP binding|guanyl ribonucleotide binding|,10,-0.6,1.62,10,-0.2,1.44,-0.4,1.62,-1.62,0.613,0,0,-1.8,0.4
ENSMUSG00000075229,CCDC58,coiled-coil domain containing 58,mitochondrion|,biological_process|,molecular_function|,10,0.1,0.662,10,0.7,3.22,0.3,1.62,1.62,0.613,0,0,-0.6,1.7
ENSMUSG00000025794,RPL14,ribosomal protein L14,intracellular|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,rRNA processing|translation|ribosomal large subunit biogenesis|,structural constituent of ribosome|poly(A) RNA binding|,7,0.1,0.511,8,-0.6,2.56,0.2,1.62,1.62,0.613,0,0,-2,0.8
ENSMUSG00000052374,ACTN2,actinin alpha 2,cytoplasm|striated muscle thin filament|focal adhesion|sarcomere|Z disc|Z disc|filopodium|cortical actin cytoskeleton|extracellular vesicular exosome|,muscle contraction|microspike assembly|regulation of membrane potential|negative regulation of potassium ion transport|positive regulation of potassium ion transport|focal adhesion assembly|protein homotetramerization|negative regulation of potassium ion transmembrane transporter activity|positive regulation of potassium ion transmembrane transporter activity|negative regulation of protein localization to cell surface|positive regulation of receptor activity|regulation of RNA biosynthetic process|,"actin binding|calcium ion binding|protein binding|cytoskeletal protein binding|cytoskeletal protein binding|LIM domain binding|ligand-dependent nuclear receptor transcription coactivator activity|thyroid hormone receptor coactivator activity|protein binding, bridging|titin binding|identical protein binding|protein homodimerization activity|ion channel binding|metal ion binding|protein dimerization activity|actin filament binding|actin filament binding|FATZ binding|titin Z domain binding|",10,0,0,10,0.4,3.25,0.3,1.61,1.61,0.615,0,0,-0.5,1.6
ENSMUSG00000034248,SLC25A37,"solute carrier family 25, member 37",mitochondrion|,None,None,10,0.2,2.07,10,0.8,0.237,0.2,1.59,1.59,0.617,0,0,-0.4,1.9
ENSMUSG00000026904,SLC4A10,"solute carrier family 4, sodium bicarbonate cotransporter-like, member 10",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,protein glycosylation|transport|ion transport|sodium ion transport|anion transport|regulation of pH|ion transmembrane transport|,transporter activity|inorganic anion exchanger activity|anion transmembrane transporter activity|symporter activity|antiporter activity|anion:anion antiporter activity|,10,0.3,3.18,10,-0.4,0.796,0.2,1.58,1.58,0.619,0,0,-1.5,1.2
ENSMUSG00000039670,OXLD1,oxidoreductase like domain containing 1,mitochondrion|,biological_process|,molecular_function|,10,0.1,0.294,10,0.2,1.64,0.2,1.57,1.57,0.62,0,0,-1,1.5
ENSMUSG00000053291,RAB4B,"RAB4B, member RAS oncogene family",mitochondrion|plasma membrane|membrane|insulin-responsive compartment|perinuclear region of cytoplasm|recycling endosome|,transport|small GTPase mediated signal transduction|protein transport|glucose import|,nucleotide binding|GTP binding|,10,0.1,0.408,10,-0.4,1.88,-0.3,1.56,-1.56,0.621,0,0,-1.7,0.7
ENSMUSG00000062169,CNIH4,cornichon homolog 4 (Drosophila),endoplasmic reticulum|membrane|integral component of membrane|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,-0.3,2.23,-0.2,1.55,-1.55,0.622,0,0,-1.6,0.8
ENSMUSG00000041986,ELMOD1,ELMO/CED-12 domain containing 1,cytoskeleton|,phagocytosis|positive regulation of GTPase activity|,GTPase activator activity|,10,0.8,2.25,10,-0.3,0.785,0.2,1.55,1.55,0.622,0,0,-0.7,1.9
ENSMUSG00000004568,ARHGEF18,rho/rac guanine nucleotide exchange factor (GEF) 18,cytoplasm|apical part of cell|,small GTPase mediated signal transduction|regulation of cell shape|actin cytoskeleton organization|regulation of Rho protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0.2,2.43,10,0,0,0.2,1.55,1.55,0.622,0,0,-0.5,1.8
ENSMUSG00000017817,JPH2,junctophilin 2,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|Z disc|junctional membrane complex|,positive regulation of cytosolic calcium ion concentration|multicellular organismal development|regulation of cardiac muscle tissue development|calcium ion homeostasis|positive regulation of ryanodine-sensitive calcium-release channel activity|calcium ion transmembrane transport|calcium ion transmembrane transport|,"phosphatidylserine binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-5-phosphate binding|calcium-release channel activity|calcium-release channel activity|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-4-phosphate binding|phosphatidic acid binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0.3,0.847,10,0.9,0.919,0.3,1.55,1.55,0.622,0,0,-0.3,1.9
ENSMUSG00000052861,DNAH6,"dynein, axonemal, heavy chain 6",cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,-0.2,2.4,10,0,0,-0.2,1.54,-1.54,0.624,0,0,-1.5,1
ENSMUSG00000068876,CGN,cingulin,tight junction|tight junction|tight junction|myosin complex|cell junction|apical junction complex|,microtubule cytoskeleton organization|epithelial cell morphogenesis|tight junction assembly|,motor activity|protein binding|microtubule binding|,10,0.2,0.812,10,0.4,0.855,0.2,1.5,1.5,0.629,0,0,-0.7,1.7
ENSMUSG00000058569,TMED9,transmembrane emp24 protein transport domain containing 9,Golgi membrane|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,transport|Golgi organization|positive regulation of organelle organization|protein transport|COPI coating of Golgi vesicle|,syntaxin binding|,10,0.3,1.26,10,0.9,0.521,0.3,1.49,1.49,0.631,0,0,-0.5,1.9
ENSMUSG00000015090,PTGDS,prostaglandin D2 synthase (brain),extracellular region|extracellular region|extracellular space|nucleus|cytoplasm|endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|membrane|extracellular vesicular exosome|,"prostaglandin biosynthetic process|prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|transport|regulation of circadian sleep/wake cycle, sleep|",prostaglandin-D synthase activity|prostaglandin-D synthase activity|transporter activity|retinoid binding|retinoid binding|fatty acid binding|isomerase activity|small molecule binding|,10,0,0,10,0.5,3.1,0.4,1.48,1.48,0.632,0,0,-0.6,1.7
ENSMUSG00000030117,GDF3,growth differentiation factor 3,extracellular region|extracellular space|cytoplasm|,skeletal system development|eye development|in utero embryonic development|in utero embryonic development|response to dietary excess|signal transduction|endoderm development|endoderm development|mesoderm development|mesoderm development|regulation of cell fate commitment|negative regulation of BMP signaling pathway|notochord development|somite rostral/caudal axis specification|growth|negative regulation of epidermal cell differentiation|formation of anatomical boundary|primitive streak formation|,cytokine activity|protein binding|growth factor activity|protein kinase binding|,10,0.1,0.096,10,0.2,1.86,0.2,1.48,1.48,0.632,0,0,-0.8,1.6
ENSMUSG00000049493,PLS1,plastin 1 (I-isoform),cytoplasm|extracellular vesicular exosome|,biological_process|,actin binding|calcium ion binding|metal ion binding|,10,0.3,0.78,10,0.9,1.77,0.3,1.48,1.48,0.632,0,0,-0.7,1.9
ENSMUSG00000020056,CCDC53,coiled-coil domain containing 53,actin cytoskeleton|intracellular membrane-bounded organelle|WASH complex|,biological_process|,molecular_function|,10,-0.2,1.51,10,-0.1,0.184,-0.2,1.48,-1.48,0.632,0,0,-1.3,1.6
ENSMUSG00000032513,GORASP1,golgi reassembly stacking protein 1,cytoplasm|Golgi apparatus|membrane|,transport|Golgi organization|protein transport|negative regulation of dendrite morphogenesis|,molecular_function|,10,0.2,1.56,10,0.3,0.0427,0.2,1.47,1.47,0.633,0,0,-1.2,1.4
ENSMUSG00000032314,ETFA,"electron transferring flavoprotein, alpha polypeptide",mitochondrion|mitochondrion|mitochondrial electron transfer flavoprotein complex|extracellular vesicular exosome|,transport|oxidation-reduction process|,electron carrier activity|electron carrier activity|oxidoreductase activity|flavin adenine dinucleotide binding|,10,0.2,0.674,10,0.3,1.07,0.2,1.46,1.46,0.635,0,0,-0.9,1.5
ENSMUSG00000024072,YIPF4,"Yip1 domain family, member 4",endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,biological_process|,molecular_function|,10,0.4,1.19,10,0.2,0.925,0.3,1.46,1.46,0.635,0,0,-1.5,1.2
ENSMUSG00000032202,RAB27A,"RAB27A, member RAS oncogene family",photoreceptor outer segment|intracellular|lysosome|endosome|late endosome|Golgi apparatus|membrane|apical plasma membrane|secretory granule|secretory granule|dendrite|secretory granule membrane|multivesicular body membrane|melanosome|melanosome|extracellular vesicular exosome|exocytic vesicle|,GTP catabolic process|protein targeting|exocytosis|small GTPase mediated signal transduction|blood coagulation|protein transport|vesicle-mediated transport|antigen processing and presentation|melanocyte differentiation|melanosome localization|melanosome transport|cytotoxic T cell degranulation|natural killer cell degranulation|pigmentation|positive regulation of exocytosis|pigment granule localization|pigment granule transport|multivesicular body sorting pathway|,nucleotide binding|GTPase activity|protein binding|GTP binding|GTP binding|GDP binding|protein domain specific binding|myosin V binding|,10,-0.3,1.87,10,-0.1,0.116,-0.2,1.46,-1.46,0.635,0,0,-1.4,1.1
ENSMUSG00000033429,MCEE,methylmalonyl CoA epimerase,mitochondrion|,L-methylmalonyl-CoA metabolic process|,methylmalonyl-CoA epimerase activity|isomerase activity|metal ion binding|,10,-0.5,3.85,10,0.3,1.13,-0.3,1.45,-1.45,0.636,0,0,-1.7,0.7
ENSMUSG00000028165,CISD2,CDGSH iron sulfur domain 2,mitochondrion|mitochondrial outer membrane|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|protein complex|perinuclear region of cytoplasm|,mitochondrion degradation|autophagy|multicellular organismal aging|regulation of autophagy|,"protein homodimerization activity|poly(A) RNA binding|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,0.2,2.06,10,0,0,0.1,1.44,1.44,0.637,0,0,-1.1,1.5
ENSMUSG00000023022,LIMA1,LIM domain and actin binding 1,stress fiber|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|actin cytoskeleton|actin cytoskeleton|,negative regulation of actin filament depolymerization|ruffle organization|actin filament bundle assembly|,actin binding|actin monomer binding|zinc ion binding|metal ion binding|actin filament binding|,10,0.1,0.265,10,1,2.5,0.2,1.44,1.44,0.637,0,0,-0.2,2
ENSMUSG00000037428,VGF,VGF nerve growth factor inducible,extracellular region|extracellular space|cell|secretory granule membrane|cytoplasmic vesicle|neuron projection|neuronal cell body|,ovarian follicle development|response to dietary excess|response to dietary excess|generation of precursor metabolites and energy|generation of precursor metabolites and energy|response to cold|sexual reproduction|insulin secretion|response to insulin|glucose homeostasis|penile erection|regulation of neuronal synaptic plasticity|,neuropeptide hormone activity|,10,-0.5,1.04,10,0.5,4.22,0.5,1.42,1.42,0.64,0,0,-1.2,1.6
ENSMUSG00000035557,KRT17,keratin 17,cytoplasm|intermediate filament|extracellular vesicular exosome|cell periphery|,morphogenesis of an epithelium|signal transduction|positive regulation of cell growth|keratinization|intermediate filament organization|positive regulation of translation|positive regulation of hair follicle development|,structural molecule activity|protein binding|MHC class II receptor activity|MHC class II protein binding|,10,-0.4,2.64,10,0,0,-0.3,1.42,-1.42,0.64,0,0,-1.7,0.8
ENSMUSG00000048920,FKRP,fukutin related protein,extracellular region|extracellular space|extracellular space|endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|Golgi apparatus|plasma membrane|dystrophin-associated glycoprotein complex|membrane|integral component of membrane|sarcolemma|,glycoprotein biosynthetic process|protein processing|,transferase activity|Kdo transferase activity|,10,0.1,0.761,10,0.6,1.11,0.1,1.42,1.42,0.64,0,0,-0.5,1.8
ENSMUSG00000049173,MYOZ3,myozenin 3,cytoplasm|Z disc|,None,protein binding|,9,0.3,2.44,9,0,0,0.2,1.4,1.4,0.643,0,0,-0.6,1.8
ENSMUSG00000019359,GDPD2,glycerophosphodiester phosphodiesterase domain containing 2,cytoplasm|cytoskeleton|plasma membrane|membrane|integral component of membrane|,glycerol metabolic process|lipid metabolic process|,phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|metal ion binding|glycerophosphoinositol inositolphosphodiesterase activity|,10,-0.2,1.55,10,0.3,2.12,0.2,1.39,1.39,0.644,0,0,-1.1,1.2
ENSMUSG00000024887,ASAH2,N-acylsphingosine amidohydrolase 2,mitochondrion|plasma membrane|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|apoptotic process|cell proliferation|response to organic substance|,hydrolase activity|ceramidase activity|,10,0.2,1.42,10,-0.5,0.878,0.2,1.38,1.38,0.646,0,0,-1.5,1.2
ENSMUSG00000028830,AU040320,expressed sequence AU040320,membrane|integral component of membrane|cytoplasmic vesicle|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.4,0.374,10,-0.9,2.24,-0.5,1.37,-1.37,0.647,0,0,-2,1
ENSMUSG00000041115,IQSEC2,IQ motif and Sec7 domain 2,nucleus|cytoplasm|cell junction|,actin cytoskeleton organization|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,ARF guanyl-nucleotide exchange factor activity|protein binding|,10,-0.4,3.67,10,0.4,1.86,-0.4,1.36,-1.36,0.649,0,0,-1.6,1.1
ENSMUSG00000006464,BBS1,Bardet-Biedl syndrome 1 (human),centrosome|motile cilium|BBSome|BBSome|ciliary basal body|,microtubule cytoskeleton organization|neuron migration|retina homeostasis|retina homeostasis|sensory perception of smell|protein localization|photoreceptor cell morphogenesis|fertilization|dendrite development|striatum development|hippocampus development|cerebral cortex development|adult behavior|nonmotile primary cilium assembly|nonmotile primary cilium assembly|nonmotile primary cilium assembly|multicellular organism growth|intraciliary retrograde transport|olfactory behavior|cilium assembly|cilium assembly|hormone metabolic process|Golgi to plasma membrane protein transport|cellular lipid metabolic process|photoreceptor cell maintenance|brain morphogenesis|cartilage development|cilium morphogenesis|regulation of cilium beat frequency involved in ciliary motility|protein localization to cilium|,RNA polymerase II repressing transcription factor binding|receptor binding|patched binding|smoothened binding|phosphoprotein binding|,10,-0.2,0.239,10,-0.3,1.27,-0.2,1.34,-1.34,0.651,0,0,-1.5,1.1
ENSMUSG00000044444,PFN3,profilin 3,cellular_component|nucleus|cytoplasm|cytoskeleton|,purine nucleoside transmembrane transport|ADP transport|ATP transport|actin cytoskeleton organization|ion transmembrane transport|nucleotide transmembrane transport|,actin binding|ATP:ADP antiporter activity|protein binding|lipid binding|,10,-0.4,1.81,10,-0.1,0.2,-0.3,1.34,-1.34,0.651,0,0,-1.7,0.6
ENSMUSG00000070980,ACTL7B,actin-like 7b,cytoplasm|cytoskeleton|,None,None,6,-0.2,0.236,6,0.9,3.71,0.9,1.33,1.33,0.653,0,0,-1.3,2
ENSMUSG00000030214,PLBD1,phospholipase B domain containing 1,cellular_component|lysosome|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.2,1.4,10,0.1,0.152,0.2,1.33,1.33,0.653,0,0,-1,1.5
ENSMUSG00000039096,RSAD1,radical S-adenosyl methionine domain containing 1,cytoplasm|mitochondrion|,porphyrin-containing compound biosynthetic process|oxidation-reduction process|,"catalytic activity|coproporphyrinogen oxidase activity|oxidoreductase activity|short-branched-chain-acyl-CoA dehydrogenase activity|very-long-chain-acyl-CoA dehydrogenase activity|4-methyloctanoyl-CoA dehydrogenase activity|naphthyl-2-methyl-succinyl-CoA dehydrogenase activity|2-methylhexanoyl-CoA dehydrogenase activity|propionyl-CoA dehydrogenase activity|thiol-driven fumarate reductase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity|coenzyme F420-dependent 2,4-dinitrophenol reductase activity|medium-chain-acyl-CoA dehydrogenase activity|",10,0.2,0.866,10,0.3,0.824,0.2,1.32,1.32,0.654,0,0,-0.7,1.7
ENSMUSG00000020029,NUDT4,nudix (nucleoside diphosphate linked moiety X)-type motif 4,cellular_component|cytoplasm|,None,"RNA binding|thiamine-pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|diphosphoinositol-polyphosphate diphosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|snoRNA binding|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|inositol diphosphate tetrakisphosphate diphosphatase activity|inositol bisdiphosphate tetrakisphosphate diphosphatase activity|inositol diphosphate pentakisphosphate diphosphatase activity|inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity|inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity|inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity|inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity|inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity|inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity|",10,0.2,1.22,10,1.1,2.31,0.2,1.32,1.32,0.654,0,0,-1,2
ENSMUSG00000048498,CD300E,CD300e antigen,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,immune system process|biological_process|,molecular_function|,10,0.1,1.09,10,0.1,0.345,0.1,1.32,1.32,0.654,0,0,-0.7,1.8
ENSMUSG00000019852,D10BWG1379E,"DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed",trans-Golgi network|membrane|integral component of membrane|,negative regulation of phosphatase activity|vesicle-mediated transport|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|,10,-0.6,3.45,10,0,0,-0.4,1.31,-1.31,0.656,0,0,-1.9,0.3
ENSMUSG00000002847,PLA1A,phospholipase A1 member A,acrosomal membrane|extracellular region|extracellular vesicular exosome|,lipid metabolic process|biological_process|lipid catabolic process|,"catalytic activity|phospholipase activity|phosphatidylcholine 1-acylhydrolase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.1,1.01,10,-0.2,0.49,-0.1,1.31,-1.31,0.656,0,0,-1.4,1.3
ENSMUSG00000048981,KRT31,keratin 31,extracellular space|intermediate filament|,None,structural molecule activity|,10,0.5,2.49,10,0.1,0.197,0.2,1.28,1.28,0.66,0,0,-0.8,1.8
ENSMUSG00000004630,PCP2,Purkinje cell protein 2 (L7),neuronal cell body|,rhodopsin mediated signaling pathway|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|GTPase regulator activity|,10,0.3,2.23,10,0,0,0.2,1.27,1.27,0.661,0,0,-0.7,1.7
ENSMUSG00000021662,ARHGEF28,Rho guanine nucleotide exchange factor (GEF) 28,cytoplasm|plasma membrane|membrane|,central nervous system neuron axonogenesis|cell differentiation|regulation of Rho protein signal transduction|intracellular signal transduction|neurofilament cytoskeleton organization|,RNA binding|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|metal ion binding|,10,-0.1,0.125,10,-0.8,3.85,-0.5,1.27,-1.27,0.661,0,0,-2,0.2
ENSMUSG00000021608,LPCAT1,lysophosphatidylcholine acyltransferase 1,endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|lipid particle|membrane|membrane|integral component of membrane|,lipid metabolic process|metabolic process|phospholipid biosynthetic process|phosphatidylcholine acyl-chain remodeling|surfactant homeostasis|positive regulation of protein catabolic process|retina development in camera-type eye|negative regulation of phosphatidylcholine biosynthetic process|,"calcium ion binding|transferase activity|transferase activity, transferring acyl groups|metal ion binding|1-alkenylglycerophosphocholine O-acyltransferase activity|1-acylglycerophosphocholine O-acyltransferase activity|1-acylglycerophosphocholine O-acyltransferase activity|1-alkylglycerophosphocholine O-acyltransferase activity|1-alkylglycerophosphocholine O-acetyltransferase activity|",10,0.1,0.802,10,0.6,0.915,0.1,1.27,1.27,0.661,0,0,-0.5,1.9
ENSMUSG00000030922,LYRM1,LYR motif containing 1,mitochondrion|,biological_process|,molecular_function|,10,0.2,2.8,10,0,0,0.2,1.27,1.27,0.661,0,0,-0.9,1.6
ENSMUSG00000060002,CHPT1,choline phosphotransferase 1,Golgi apparatus|membrane|integral component of membrane|,lipid metabolic process|phosphatidylcholine biosynthetic process|phosphatidylcholine biosynthetic process|CDP-choline pathway|platelet activating factor biosynthetic process|phospholipid biosynthetic process|,"diacylglycerol cholinephosphotransferase activity|transferase activity|phosphotransferase activity, for other substituted phosphate groups|metal ion binding|",10,0.1,1.05,10,1.1,1.49,0.2,1.27,1.27,0.661,0,0,-0.3,2
ENSMUSG00000002342,TMEM161A,transmembrane protein 161A,cellular_component|membrane|integral component of membrane|,response to retinoic acid|cellular response to oxidative stress|cellular response to UV|positive regulation of DNA repair|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|,molecular_function|,10,-0.2,2.33,10,0,0,-0.2,1.26,-1.26,0.663,0,0,-1.3,1.2
ENSMUSG00000030681,MVP,major vault protein,nucleus|cytoplasm|cytoskeleton|membrane|ribonucleoprotein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,cell proliferation|negative regulation of signaling|negative regulation of protein autophosphorylation|ERBB signaling pathway|negative regulation of protein tyrosine kinase activity|protein activation cascade|,protein kinase binding|protein phosphatase binding|,10,0.1,0.678,10,0.2,0.866,0.1,1.26,1.26,0.663,0,0,-0.9,1.8
ENSMUSG00000035226,RIMS4,regulating synaptic membrane exocytosis 4,cell junction|synapse|synaptic membrane|,transport|neurotransmitter transport|exocytosis|regulation of membrane potential|regulation of synaptic vesicle exocytosis|,ion channel binding|,10,0,0,10,0.7,3,0.4,1.25,1.25,0.664,0,0,-0.3,1.8
ENSMUSG00000019518,AP4M1,"adaptor-related protein complex AP-4, mu 1",Golgi apparatus|trans-Golgi network|trans-Golgi network|coated pit|membrane|clathrin adaptor complex|extracellular vesicular exosome|,transport|intracellular protein transport|intracellular protein transport|Golgi to endosome transport|protein transport|vesicle-mediated transport|,None,10,0.2,1.66,10,-0.2,0.32,0.1,1.24,1.24,0.666,0,0,-1.6,1
ENSMUSG00000024530,SLMO1,slowmo homolog 1 (Drosophila),mitochondrion|mitochondrial intermembrane space|,phospholipid transport|,phosphatidic acid transporter activity|,10,-0.2,0.894,10,-0.1,0.505,-0.2,1.24,-1.24,0.666,0,0,-1.4,1.2
ENSMUSG00000038224,SERPINF2,"serine (or cysteine) peptidase inhibitor, clade F, member 2",extracellular region|fibrinogen complex|extracellular space|extracellular space|cell surface|extracellular vesicular exosome|blood microparticle|,regulation of blood vessel size by renin-angiotensin|acute-phase response|negative regulation of peptidase activity|negative regulation of plasminogen activation|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|collagen fibril organization|positive regulation of collagen biosynthetic process|positive regulation of collagen biosynthetic process|positive regulation of cell differentiation|positive regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|blood vessel morphogenesis|positive regulation of smooth muscle cell proliferation|positive regulation of stress fiber assembly|negative regulation of fibrinolysis|positive regulation of ERK1 and ERK2 cascade|positive regulation of transforming growth factor beta production|positive regulation of transforming growth factor beta production|,protease binding|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|protein homodimerization activity|,10,-0.2,1.27,10,-0.1,0.18,-0.2,1.22,-1.22,0.669,0,0,-1.3,1.4
ENSMUSG00000025602,ZFP202,zinc finger protein 202,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|metal ion binding|,10,-0.3,2.62,10,0.3,2.93,0.3,1.22,1.22,0.669,0,0,-0.8,1.8
ENSMUSG00000006276,EPS15L1,epidermal growth factor receptor pathway substrate 15-like 1,nucleus|plasma membrane|coated pit|membrane|membrane|clathrin coat of coated pit|,endocytosis|,calcium ion binding|protein binding|metal ion binding|,10,0.2,1.79,10,-0.1,0.194,0.2,1.21,1.21,0.67,0,0,-1.1,1.4
ENSMUSG00000022101,FGF17,fibroblast growth factor 17,extracellular region|,multicellular organismal development|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|,receptor binding|fibroblast growth factor receptor binding|type 1 fibroblast growth factor receptor binding|type 2 fibroblast growth factor receptor binding|growth factor activity|,9,-0.2,1.93,9,0.1,0.547,0.1,1.19,1.19,0.674,0,0,-1.2,1.6
ENSMUSG00000020268,LYRM7,LYR motif containing 7,mitochondrion|,biological_process|,molecular_function|,4,0.4,0.825,4,-0.6,1.87,-0.2,1.19,-1.19,0.674,0,0,-2,1.3
ENSMUSG00000021371,MCUR1,mitochondrial calcium uniporter regulator 1,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial inner membrane|,transport|ion transport|calcium ion transport|mitochondrial calcium ion transport|positive regulation of mitochondrial calcium ion concentration|calcium ion import|,molecular_function|,10,-0.3,1.11,10,-0.1,0.23,-0.2,1.17,-1.17,0.677,0,0,-1.7,0.8
ENSMUSG00000049550,CLIP1,CAP-GLY domain containing linker protein 1,cytoplasm|centrosome|cytoskeleton|microtubule|microtubule|cytoplasmic microtubule|microtubule cytoskeleton|membrane|cytoplasmic vesicle|microtubule plus-end|microtubule plus-end|cell projection|macropinosome|,microtubule bundle formation|transport|positive regulation of microtubule polymerization|,nucleic acid binding|protein binding|microtubule binding|microtubule binding|zinc ion binding|tubulin binding|metal ion binding|microtubule plus-end binding|microtubule plus-end binding|,10,-0.2,1.54,10,0.3,1.09,-0.2,1.17,-1.17,0.677,0,0,-1.1,1.4
ENSMUSG00000052310,SLC39A1,"solute carrier family 39 (zinc transporter), member 1",plasma membrane|membrane|integral component of membrane|,transport|ion transport|zinc ion transport|metal ion transport|transmembrane transport|zinc ion transmembrane transport|zinc ion transmembrane transport|divalent inorganic cation transport|,receptor binding|zinc ion transmembrane transporter activity|metal ion transmembrane transporter activity|,10,0.2,0.295,10,0.2,0.951,0.2,1.15,1.15,0.68,0,0,-0.7,1.7
ENSMUSG00000003062,STARD3NL,STARD3 N-terminal like,lysosomal membrane|endosome|membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,1.85,10,0,0,-0.2,1.14,-1.14,0.682,0,0,-1.6,1
ENSMUSG00000071042,RASGRP3,"RAS, guanyl releasing protein 3",cytoplasm|guanyl-nucleotide exchange factor complex|perinuclear region of cytoplasm|,Ras protein signal transduction|positive regulation of Ras GTPase activity|positive regulation of Rap GTPase activity|regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|Ras GTPase binding|Ras GTPase binding|kinase binding|Rap GTPase activator activity|metal ion binding|,10,0.1,0.624,10,0.3,1,0.2,1.14,1.14,0.682,0,0,-0.7,1.7
ENSMUSG00000067818,MYL9,"myosin, light polypeptide 9, regulatory",stress fiber|myosin complex|myosin II complex|Z disc|,None,calcium ion binding|metal ion binding|,10,0.3,0.516,10,0.4,0.916,0.3,1.14,1.14,0.682,0,0,-0.9,1.6
ENSMUSG00000059741,MYL3,"myosin, light polypeptide 3",myosin complex|A band|I band|,regulation of the force of heart contraction|regulation of striated muscle contraction|metabolic process|ventricular cardiac muscle tissue morphogenesis|cardiac muscle contraction|,motor activity|actin monomer binding|calcium ion binding|,10,-0.2,1.08,10,-0.2,0.146,-0.2,1.13,-1.13,0.683,0,0,-1.6,0.9
ENSMUSG00000030806,STX1B,syntaxin 1B,membrane|integral component of membrane|,transport|neurotransmitter transport|intracellular protein transport|protein transport|vesicle-mediated transport|regulation of exocytosis|,SNARE binding|SNAP receptor activity|protein binding|protein domain specific binding|,10,-0.6,1.86,10,0.4,2.91,0.3,1.12,1.12,0.685,0,0,-1.8,1
ENSMUSG00000052609,PLEKHG3,"pleckstrin homology domain containing, family G (with RhoGef domain) member 3",cellular_component|,biological_process|regulation of Rho protein signal transduction|,molecular_function|Rho guanyl-nucleotide exchange factor activity|,10,0.4,1.74,10,0.1,0.189,0.3,1.1,1.1,0.688,0,0,-0.6,1.7
ENSMUSG00000032946,RASGRP2,"RAS, guanyl releasing protein 2",intracellular|cytoplasm|cytosol|plasma membrane|membrane|cell junction|cell projection|neuron projection|synapse|,small GTPase mediated signal transduction|intracellular signal transduction|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|calcium ion binding|metal ion binding|,10,0.6,2.93,9,-0.1,0.0927,0.2,1.1,1.1,0.688,0,0,-1.7,1.5
ENSMUSG00000021567,NKD2,naked cuticle 2 homolog (Drosophila),cytoplasm|plasma membrane|membrane|basolateral plasma membrane|lateral plasma membrane|cytoplasmic vesicle|cell periphery|,transport|exocytosis|positive regulation of protein processing|Wnt signaling pathway|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|Golgi vesicle fusion to target membrane|protein targeting to plasma membrane|positive regulation of establishment of protein localization to plasma membrane|negative regulation of canonical Wnt signaling pathway|,calcium ion binding|growth factor binding|ubiquitin protein ligase binding|metal ion binding|,10,0.1,0.101,10,0.4,2.55,0.3,1.08,1.08,0.691,0,0,-0.7,1.9
ENSMUSG00000030064,FRMD4B,FERM domain containing 4B,ruffle|extracellular space|cytoplasm|cytoskeleton|,establishment of epithelial cell polarity|,protein binding|,10,-0.1,0.371,10,-0.3,1.4,-0.1,1.06,-1.06,0.695,0,0,-1.5,1.2
ENSMUSG00000032489,KIF9,kinesin family member 9,podosome|cytoplasm|cytoskeleton|kinesin complex|microtubule|vesicle|,microtubule-based movement|extracellular matrix disassembly|regulation of podosome assembly|organelle disassembly|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|protein dimerization activity|,9,0.3,1.56,9,-0.6,1.78,0.3,1.05,1.05,0.697,0,0,-1.8,1.1
ENSMUSG00000095861,DNAH7C,"dynein, axonemal, heavy chain 7C",cellular_component|,biological_process|,molecular_function|,10,-0.6,2.16,10,0.3,1.65,-0.3,1.05,-1.05,0.697,0,0,-1.8,0.9
ENSMUSG00000039285,AZI2,5-azacytidine induced gene 2,cytoplasm|,mitotic cell cycle|cytokine production|I-kappaB kinase/NF-kappaB signaling|interferon-alpha production|interferon-gamma production|interleukin-6 production|tumor necrosis factor production|T cell activation|T cell activation|dendritic cell proliferation|dendritic cell differentiation|,protein binding|,10,0,0,10,-0.4,2.21,-0.2,1.04,-1.04,0.698,0,0,-2,0.3
ENSMUSG00000000295,HDDC2,HD domain containing 2,mitochondrion|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.2,0.174,10,-0.3,0.964,-0.3,1.01,-1.01,0.703,0,0,-1.7,0.8
ENSMUSG00000037542,ALDH8A1,"aldehyde dehydrogenase 8 family, member A1",intracellular|cytoplasm|extracellular vesicular exosome|,metabolic process|retinoic acid metabolic process|retinal metabolic process|retinal metabolic process|9-cis-retinoic acid biosynthetic process|oxidation-reduction process|,"retinal dehydrogenase activity|retinal dehydrogenase activity|3-chloroallyl aldehyde dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|1-hydroxy-2-naphthaldehyde dehydrogenase activity|cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity|2-carboxybenzaldehyde dehydrogenase activity|trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity|benzaldehyde dehydrogenase activity|2-naphthaldehyde dehydrogenase activity|1-naphthaldehyde dehydrogenase activity|4-hydroxymethylsalicyaldehyde dehydrogenase activity|3-methylsalicylaldehyde dehydrogenase activity|oxoglutarate dehydrogenase [NAD(P)+] activity|oxoglutarate dehydrogenase (NAD+) activity|pyruvate dehydrogenase [NAD(P)+] activity|pyruvate dehydrogenase (NAD+) activity|citronellal dehydrogenase activity|geranial dehydrogenase activity|N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity|glyceraldehyde dehydrogenase (NADP) activity|N-acetyl-gamma-aminoadipyl-phosphate reductase activity|glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity|2,5-dioxovalerate dehydrogenase (NAD+) activity|medium-chain-aldehyde dehydrogenase activity|",10,0,0,10,1.4,4.05,1.4,1.01,1.01,0.703,0,0,-0.3,3
ENSMUSG00000022831,HCLS1,hematopoietic cell specific Lyn substrate 1,nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|mitochondrion|,negative regulation of transcription from RNA polymerase II promoter|positive regulation of cell proliferation|response to hormone|positive regulation of phosphatidylinositol 3-kinase signaling|actin filament polymerization|erythrocyte differentiation|regulation of actin filament polymerization|positive regulation of granulocyte differentiation|positive regulation of granulocyte differentiation|positive regulation of peptidyl-serine phosphorylation|positive regulation of tyrosine phosphorylation of STAT protein|positive regulation of transcription factor import into nucleus|positive regulation of macrophage differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of protein kinase B signaling|cellular response to cytokine stimulus|negative regulation of leukocyte apoptotic process|,RNA polymerase II transcription factor binding|actin binding|protein binding|SH3 domain binding|SH3 domain binding|protein kinase binding|protein complex binding|,10,0.1,0.733,10,1.2,1.59,0.2,1.01,1.01,0.703,0,0,-0.2,2
ENSMUSG00000042787,EXOG,"endo/exonuclease (5'-3'), endonuclease G-like",mitochondrion|mitochondrial inner membrane|membrane|,"DNA catabolic process, endonucleolytic|",nucleic acid binding|nuclease activity|endonuclease activity|hydrolase activity|metal ion binding|,10,0.3,1.78,10,-0.3,0.996,0.3,1,1,0.705,0,0,-1.2,1.3
ENSMUSG00000039254,POMT1,protein-O-mannosyltransferase 1,acrosomal vesicle|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|sarcoplasmic reticulum|,protein O-linked glycosylation|extracellular matrix organization|,"mannosyltransferase activity|dolichyl-phosphate-mannose-protein mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0.2,1.85,10,-0.2,0.248,0.2,1,1,0.705,0,0,-1.1,1.5
ENSMUSG00000042770,HEBP1,heme binding protein 1,cytoplasm|mitochondrion|cytosol|extracellular vesicular exosome|,heme metabolic process|,heme binding|,10,-0.1,0.404,10,-0.2,0.996,-0.1,0.997,-0.997,0.705,0,0,-1.4,1.4
ENSMUSG00000001864,AIF1L,allograft inflammatory factor 1-like,cytoplasm|cytoskeleton|actin filament|plasma membrane|focal adhesion|actin cytoskeleton|membrane|cell projection|protein complex|extracellular vesicular exosome|,biological_process|,actin binding|calcium ion binding|metal ion binding|actin filament binding|,10,0.2,1.22,10,0.1,0.103,0.2,0.993,0.993,0.706,0,0,-0.7,1.8
ENSMUSG00000032333,STOML1,stomatin-like 1,cellular_component|membrane|integral component of membrane|,SMAD protein signal transduction|,molecular_function|,10,-0.2,1.4,10,0,0,-0.1,0.99,-0.99,0.707,0,0,-1.2,1.3
ENSMUSG00000048915,EFNA5,ephrin A5,plasma membrane|membrane|anchored component of membrane|anchored component of external side of plasma membrane|anchored component of plasma membrane|,multicellular organismal development|nervous system development|axon guidance|axon guidance|brain development|regulation of cell-cell adhesion|regulation of cell-cell adhesion|cell differentiation|retinal ganglion cell axon guidance|regulation of Rac GTPase activity|regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|regulation of actin cytoskeleton organization|ephrin receptor signaling pathway|ephrin receptor signaling pathway|positive regulation of peptidyl-tyrosine phosphorylation|negative chemotaxis|regulation of focal adhesion assembly|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of microtubule cytoskeleton organization|,protein binding|chemorepellent activity|ephrin receptor binding|ephrin receptor binding|,10,0.1,0.768,10,0.5,0.385,0.1,0.955,0.955,0.712,0,0,-0.9,1.7
ENSMUSG00000030303,FAR2,fatty acyl CoA reductase 2,peroxisome|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|wax biosynthetic process|long-chain fatty-acyl-CoA metabolic process|oxidation-reduction process|,oxidoreductase activity|long-chain-fatty-acyl-CoA reductase activity|fatty-acyl-CoA reductase (alcohol-forming) activity|,10,-0.2,1.11,10,-0.1,0.08,-0.1,0.947,-0.947,0.714,0,0,-1.4,1.2
ENSMUSG00000057604,LMCD1,LIM and cysteine-rich domains 1,extracellular space|nucleus|cytoplasm|extracellular matrix|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of cardiac muscle hypertrophy|regulation of cardiac muscle hypertrophy|positive regulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signaling cascade|regulation of RNA biosynthetic process|",transcription corepressor activity|protein binding|zinc ion binding|metal ion binding|,10,-0.2,0.75,10,-0.1,0.368,-0.2,0.942,-0.942,0.715,0,0,-1.7,0.9
ENSMUSG00000026632,TATDN3,TatD DNase domain containing 3,nucleus|mitochondrion|,DNA catabolic process|nucleic acid phosphodiester bond hydrolysis|,"nuclease activity|deoxyribonuclease activity|hydrolase activity|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|metal ion binding|",10,0.2,0.679,10,-0.2,0.552,0.2,0.937,0.937,0.716,0,0,-1,1.6
ENSMUSG00000021493,PDLIM7,PDZ and LIM domain 7,stress fiber|ruffle|nucleus|cytoplasm|cytoskeleton|focal adhesion|actin cytoskeleton|,ossification|multicellular organismal development|actin cytoskeleton organization|cell differentiation|positive regulation of osteoblast differentiation|,protein binding|zinc ion binding|metal ion binding|,10,0.2,0.501,10,0.2,0.491,0.2,0.91,0.91,0.72,0,0,-1.1,1.6
ENSMUSG00000033389,ARHGAP44,Rho GTPase activating protein 44,intracellular|cytoplasm|endosome|cell junction|leading edge membrane|cell projection|synapse|,signal transduction|,GTPase activator activity|phospholipid binding|,9,-0.7,3.12,9,0,0,-0.2,0.898,-0.898,0.722,0,0,-2,0.5
ENSMUSG00000028845,TEKT2,tektin 2,nucleus|cytoplasm|cytoskeleton|microtubule|cilium|cell projection|,cell projection organization|sperm motility|inner dynein arm assembly|,None,10,-0.2,2.23,10,0.2,0.697,-0.2,0.887,-0.887,0.724,0,0,-1.4,1.2
ENSMUSG00000069170,GPR98,G protein-coupled receptor 98,stereocilia ankle link complex|extracellular region|cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|extracellular vesicular exosome|,cell communication|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|multicellular organismal development|nervous system development|visual perception|sensory perception of sound|sensory perception of sound|single organismal cell-cell adhesion|photoreceptor cell maintenance|maintenance of organ identity|inner ear development|neurological system process|neurological system process|response to stimulus|detection of mechanical stimulus involved in sensory perception of sound|sensory perception of light stimulus|inner ear receptor stereocilium organization|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcium ion binding|calcium ion binding|myosin binding|,9,0.1,0.0871,9,-0.3,1.16,-0.2,0.876,-0.876,0.726,0,0,-1.7,1.1
ENSMUSG00000020875,HOXB9,homeobox B9,nucleus|mitochondrion|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|mammary gland development|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system development|embryonic skeletal system development|canonical Wnt signaling pathway|cell chemotaxis|",DNA binding|sequence-specific DNA binding|,9,0.2,0.717,10,0.1,0.352,0.2,0.873,0.873,0.727,0,0,-1,1.7
ENSMUSG00000040140,TDRD6,tudor domain containing 6,cytoplasm|endoplasmic reticulum|ribonucleoprotein complex|chromatoid body|P granule|,multicellular organismal development|germ cell development|spermatogenesis|cell differentiation|,protein binding|,10,0.2,0.632,10,0.5,0.597,0.2,0.868,0.868,0.728,0,0,-0.6,1.9
ENSMUSG00000022516,NUDT16L1,nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1,cellular_component|cytoplasm|,biological_process|,RNA binding|hydrolase activity|snoRNA binding|poly(A) RNA binding|,10,-0.1,0.0828,10,0.3,1.58,0.3,0.866,0.866,0.728,0,0,-1,1.7
ENSMUSG00000028553,ANGPTL3,angiopoietin-like 3,extracellular region|extracellular space|cell surface|,glycerol metabolic process|fatty acid metabolic process|triglyceride metabolic process|phospholipid metabolic process|cell-matrix adhesion|signal transduction|cholesterol metabolic process|phospholipid catabolic process|negative regulation of phospholipase activity|negative regulation of phospholipase activity|lipid storage|positive regulation of cell migration|cholesterol homeostasis|cholesterol homeostasis|negative regulation of catalytic activity|positive regulation of angiogenesis|positive regulation of lipid metabolic process|artery morphogenesis|positive regulation of lipid catabolic process|negative regulation of lipoprotein lipase activity|lipid homeostasis|acylglycerol homeostasis|acylglycerol homeostasis|phospholipid homeostasis|phospholipid homeostasis|triglyceride homeostasis|triglyceride homeostasis|,enzyme inhibitor activity|phospholipase inhibitor activity|integrin binding|growth factor activity|,10,0.2,0.984,10,0.1,0.0519,0.1,0.865,0.865,0.728,0,0,-1.1,1.6
ENSMUSG00000024069,SLC30A6,"solute carrier family 30 (zinc transporter), member 6",mitochondrion|Golgi apparatus|membrane|integral component of membrane|,transport|ion transport|cation transport|zinc ion transport|Golgi to endosome transport|transmembrane transport|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|cation transmembrane transporter activity|,10,0.1,0.334,10,-0.3,1.72,-0.2,0.852,-0.852,0.731,0,0,-1.4,1.1
ENSMUSG00000015869,PRPSAP1,phosphoribosyl pyrophosphate synthetase-associated protein 1,ribose phosphate diphosphokinase complex|protein complex|,nucleotide biosynthetic process|negative regulation of kinase activity|,magnesium ion binding|ribose phosphate diphosphokinase activity|kinase binding|enzyme regulator activity|,10,0.1,0.0931,10,0.4,1.96,0.2,0.847,0.847,0.731,0,0,-0.5,1.9
ENSMUSG00000024347,PSD2,pleckstrin and Sec7 domain containing 2,membrane|integral component of membrane|cell junction|dendrite|neuronal cell body|,neuron differentiation|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,ARF guanyl-nucleotide exchange factor activity|phospholipid binding|,10,0.2,1.35,10,0,0,0.2,0.845,0.845,0.732,0,0,-0.8,1.8
ENSMUSG00000007279,SCUBE2,"signal peptide, CUB domain, EGF-like 2",extracellular region|extracellular space|extrinsic component of plasma membrane|,biological_process|,calcium ion binding|identical protein binding|,10,-0.1,0.201,10,-0.3,1.14,-0.2,0.844,-0.844,0.732,0,0,-1.5,1.1
ENSMUSG00000003178,MICAL3,"microtubule associated monooxygenase, calponin and LIM domain containing 3",nucleus|cytoplasm|cytoskeleton|,exocytosis|cytoskeleton organization|metabolic process|actin filament depolymerization|oxidation-reduction process|,"actin binding|monooxygenase activity|zinc ion binding|3-(3-hydroxyphenyl)propionate hydroxylase activity|oxidoreductase activity|4-chlorobenzaldehyde oxidase activity|3,5-xylenol methylhydroxylase activity|phenylacetate hydroxylase activity|4-nitrophenol 4-monooxygenase activity|dimethyl sulfide monooxygenase activity|alpha-pinene monooxygenase [NADH] activity|phenanthrene 9,10-monooxygenase activity|1-hydroxy-2-naphthoate hydroxylase activity|toluene 4-monooxygenase activity|xylene monooxygenase activity|dibenzothiophene monooxygenase activity|6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|chlorophenol 4-monooxygenase activity|carbon disulfide oxygenase activity|toluene 2-monooxygenase activity|1-hydroxy-2-oxolimonene 1,2-monooxygenase activity|phenanthrene 1,2-monooxygenase activity|tetrahydrofuran hydroxylase activity|styrene monooxygenase activity|toluene-4-sulfonate monooxygenase activity|toluene-sulfonate methyl-monooxygenase activity|3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|2-hydroxy-phenylacetate hydroxylase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity|phenanthrene 3,4-monooxygenase activity|toluene 3-monooxygenase activity|4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity|limonene monooxygenase activity|2-methylnaphthalene hydroxylase activity|1-methylnaphthalene hydroxylase activity|bisphenol A hydroxylase A activity|salicylate 5-hydroxylase activity|isobutylamine N-hydroxylase activity|branched-chain dodecylbenzene sulfonate monooxygenase activity|3-HSA hydroxylase activity|4-hydroxypyridine-3-hydroxylase activity|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity|6-hydroxynicotinate 3-monooxygenase activity|metal ion binding|tocotrienol omega-hydroxylase activity|thalianol hydroxylase activity|",10,-0.2,0.727,10,1.2,0.266,-0.2,0.832,-0.832,0.734,0,0,-0.9,2
ENSMUSG00000024145,PIGF,"phosphatidylinositol glycan anchor biosynthesis, class F",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|,"phosphotransferase activity, for other substituted phosphate groups|",10,0.4,1.53,10,0.1,0.325,0.4,0.831,0.831,0.734,0,0,-0.6,1.8
ENSMUSG00000019796,LRP11,low density lipoprotein receptor-related protein 11,cellular_component|membrane|integral component of membrane|,endocytosis|biological_process|,molecular_function|,10,-0.3,1.43,10,0,0,-0.2,0.83,-0.83,0.734,0,0,-1.7,0.9
ENSMUSG00000038886,MAN2A2,"mannosidase 2, alpha 2",Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|mannose metabolic process|metabolic process|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity|zinc ion binding|mannosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hydrolase activity, hydrolyzing N-glycosyl compounds|carbohydrate binding|metal ion binding|",10,-0.1,1.13,10,1.1,1.81,-0.1,0.83,-0.83,0.734,0,0,-0.7,2
ENSMUSG00000022159,RAB2B,"RAB2B, member RAS oncogene family",cellular_component|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|,transport|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|positive regulation of exocytosis|,nucleotide binding|GTP binding|,10,-0.2,1.51,10,0.3,0.462,-0.1,0.828,-0.828,0.735,0,0,-1.5,1.2
ENSMUSG00000018387,SHROOM1,shroom family member 1,cytoplasm|cytoskeleton|microtubule|myosin II complex|,cell morphogenesis|actin filament bundle assembly|,actin binding|actin filament binding|,10,-0.1,0.0182,10,0.6,2.26,0.2,0.822,0.822,0.736,0,0,-0.6,1.9
ENSMUSG00000038235,F11R,F11 receptor,plasma membrane|cell-cell junction|tight junction|microtubule cytoskeleton|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|slit diaphragm|extracellular vesicular exosome|,cell adhesion|viral process|epithelial cell differentiation|positive regulation of blood pressure|,protein binding|,10,0.1,1.19,10,0,0,0.1,0.821,0.821,0.736,0,0,-1.5,1.3
ENSMUSG00000029541,CYP2W1,"cytochrome P450, family 2, subfamily w, polypeptide 1",cellular_component|,oxidation-reduction process|,monooxygenase activity|oxidoreductase activity|metal ion binding|,10,-0.1,0.186,10,0.4,1.71,0.2,0.806,0.806,0.739,0,0,-0.8,1.7
ENSMUSG00000018326,YWHAB,"tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide",intracellular|cell|nucleus|cytoplasm|membrane|transcriptional repressor complex|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,"protein targeting|negative regulation of protein dephosphorylation|positive regulation of catalytic activity|negative regulation of transcription, DNA-templated|cytoplasmic sequestering of protein|protein heterooligomerization|oxidation-reduction process|",transcription corepressor activity|monooxygenase activity|protein binding|protein C-terminus binding|oxidoreductase activity|enzyme binding|protein domain specific binding|protein domain specific binding|protein complex binding|histone deacetylase binding|phosphoserine binding|phosphoprotein binding|,9,-0.5,2.23,9,0.4,1.41,0.3,0.796,0.796,0.741,0,0,-1.6,1.2
ENSMUSG00000039754,ALKBH4,"alkB, alkylation repair homolog 4 (E. coli)",nucleus|cytoplasm|midbody|contractile ring|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein demethylation|actomyosin structure organization|cleavage furrow ingression|oxidation-reduction process|","sulfonate dioxygenase activity|actin binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.1,0.262,10,0.3,1.07,0.2,0.793,0.793,0.742,0,0,-1.3,1.4
ENSMUSG00000020469,MYL7,"myosin, light polypeptide 7, regulatory",myosin complex|A band|dendritic spine|,None,calcium ion binding|protein binding|metal ion binding|,10,0.2,0.701,10,0.1,0.362,0.2,0.78,0.78,0.744,0,0,-0.7,1.8
ENSMUSG00000036555,IQCE,IQ motif containing E,mitochondrion|,biological_process|,molecular_function|,10,-0.1,0.343,10,-0.2,0.545,-0.1,0.777,-0.777,0.744,0,0,-1.7,1
ENSMUSG00000030500,SLC17A6,"solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6",early endosome|synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|neuron projection|synapse|,neurotransmitter uptake|transport|ion transport|sodium ion transport|neurotransmitter transport|L-glutamate transport|L-glutamate transport|transmembrane transport|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|L-glutamate transmembrane transporter activity|symporter activity|,10,-0.8,3.56,10,0,0,-0.8,0.775,-0.775,0.745,0,0,-2,0.9
ENSMUSG00000049303,SYT12,synaptotagmin XII,synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,transport|,transporter activity|,10,0,0,10,0.2,1.6,0.1,0.77,0.77,0.746,0,0,-0.9,1.7
ENSMUSG00000020388,PDLIM4,PDZ and LIM domain 4,None,actin cytoskeleton organization|,protein binding|zinc ion binding|actinin binding|metal ion binding|,10,0,0,10,0.3,3.1,0.3,0.767,0.767,0.746,0,0,-0.8,1.9
ENSMUSG00000022722,ARL6,ADP-ribosylation factor-like 6,intracellular|cytoplasm|cytoskeleton|plasma membrane|membrane|cell projection|extracellular vesicular exosome|,protein ADP-ribosylation|transport|small GTPase mediated signal transduction|Ras protein signal transduction|protein transport|Wnt signaling pathway|cell projection organization|cilium assembly|,nucleotide binding|protein binding|GTP binding|metal ion binding|,10,0.4,1.59,10,-0.2,0.71,0.3,0.762,0.762,0.747,0,0,-1,1.7
ENSMUSG00000024770,LIPN,"lipase, family member N",cellular_component|extracellular region|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|hydrolase activity, acting on ester bonds|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.1,0.238,10,0.2,0.912,0.3,0.759,0.759,0.748,0,0,-1,1.6
ENSMUSG00000025509,PNPLA2,patatin-like phospholipase domain containing 2,lipid particle|lipid particle|cytosol|plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|metabolic process|negative regulation of sequestering of triglyceride|negative regulation of sequestering of triglyceride|positive regulation of triglyceride catabolic process|positive regulation of triglyceride catabolic process|lipid catabolic process|triglyceride catabolic process|lipid storage|lipid particle organization|,triglyceride lipase activity|protein binding|hydrolase activity|,9,-0.2,1.89,9,0.1,0.373,-0.2,0.756,-0.756,0.749,0,0,-1.6,1.2
ENSMUSG00000036766,DNER,delta/notch-like EGF-related receptor,early endosome|plasma membrane|membrane|integral component of membrane|dendrite|dendrite|neuronal cell body|,Notch signaling pathway|Notch receptor processing|multicellular organismal development|glial cell differentiation|glial cell differentiation|cell differentiation|skeletal muscle fiber development|,Notch binding|calcium ion binding|,10,-0.2,1.48,10,0,0,-0.1,0.752,-0.752,0.749,0,0,-1.7,1.1
ENSMUSG00000060703,CD302,CD302 antigen,cytoplasm|cell cortex|membrane|membrane|integral component of membrane|filopodium|cell projection|,phagocytosis|,carbohydrate binding|,10,0,0,10,-0.6,1.24,-0.5,0.741,-0.741,0.751,0,0,-2,0.4
ENSMUSG00000024855,PACS1,phosphofurin acidic cluster sorting protein 1,Golgi apparatus|COPI-coated vesicle|perinuclear region of cytoplasm|,protein targeting to Golgi|positive regulation of protein binding|cellular protein localization|protein targeting to plasma membrane|,ion channel binding|,10,-0.3,1.17,10,0.3,1.98,0.2,0.741,0.741,0.751,0,0,-1.1,1.5
ENSMUSG00000056310,TYW1,tRNA-yW synthesizing protein 1 homolog (S. cerevisiae),nucleus|cytoplasm|,tRNA processing|biological_process|oxidation-reduction process|,"nucleotide binding|catalytic activity|iron ion binding|FMN binding|oxidoreductase activity|lyase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.1,0.122,10,0.4,0.994,0.1,0.74,0.74,0.752,0,0,-1,1.8
ENSMUSG00000040146,RGL3,ral guanine nucleotide dissociation stimulator-like 3,intracellular|,signal transduction|small GTPase mediated signal transduction|positive regulation of Ral GTPase activity|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|protein binding|Ral guanyl-nucleotide exchange factor activity|Ras GTPase binding|,10,0.2,0.711,10,0.8,0.721,0.2,0.74,0.74,0.752,0,0,-0.5,1.9
ENSMUSG00000031360,CTPS2,cytidine 5'-triphosphate synthase 2,mitochondrion|,pyrimidine nucleotide biosynthetic process|glutamine metabolic process|,nucleotide binding|CTP synthase activity|ATP binding|ligase activity|,10,-0.2,0.919,10,0.1,0.215,0.2,0.737,0.737,0.752,0,0,-1,1.6
ENSMUSG00000058704,MEMO1,mediator of cell motility 1,nucleus|cytosol|,regulation of microtubule-based process|,peptide binding|,10,-0.1,0.243,10,0.4,0.908,0.4,0.735,0.735,0.752,0,0,-0.7,1.8
ENSMUSG00000034285,NIPSNAP1,4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans),mitochondrion|mitochondrial inner membrane|membrane|synaptic membrane|,sensory perception of pain|,protein binding|neurotransmitter binding|,10,0,0,10,0.4,1.29,0.3,0.735,0.735,0.752,0,0,-1.3,1.4
ENSMUSG00000028173,WLS,wntless homolog (Drosophila),Golgi apparatus|membrane|integral component of membrane|cytoplasmic vesicle|dendrite membrane|dendrite cytoplasm|,mesoderm formation|multicellular organismal development|anterior/posterior axis specification|Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,protein binding|Wnt-protein binding|mu-type opioid receptor binding|,10,-0.4,0.305,10,-0.2,0.508,-0.2,0.729,-0.729,0.754,0,0,-1.8,0.7
ENSMUSG00000033701,ACBD6,acyl-Coenzyme A binding domain containing 6,cytoplasm|,biological_process|,fatty-acyl-CoA binding|molecular_function|lipid binding|,10,-0.2,1.25,10,0,0,-0.1,0.727,-0.727,0.754,0,0,-1.4,1.4
ENSMUSG00000025138,SIRT7,sirtuin 7,nucleus|nucleolus|nucleolus organizer region|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription on exit from mitosis|rRNA transcription|chromatin modification|histone H3 deacetylation|histone H4 deacetylation|","chromatin binding|histone deacetylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|metal ion binding|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|NAD+ binding|NAD-dependent histone deacetylase activity (H3-K18 specific)|",10,-0.2,0.337,10,0.4,1.51,0.2,0.725,0.725,0.754,0,0,-1.8,1
ENSMUSG00000042451,MYBPH,myosin binding protein H,cellular_component|myosin filament|,cell adhesion|biological_process|,molecular_function|,10,-0.3,1.94,10,0,0,-0.2,0.725,-0.725,0.754,0,0,-1.8,0.8
ENSMUSG00000030304,ERGIC2,ERGIC and golgi 2,nucleus|nucleolus|cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,transport|biological_process|vesicle-mediated transport|,molecular_function|,10,-0.2,1.34,10,0,0,-0.2,0.708,-0.708,0.757,0,0,-1.5,1.2
ENSMUSG00000060594,LAYN,layilin,membrane|integral component of membrane|,None,hyaluronic acid binding|carbohydrate binding|,10,0.1,0.855,10,-0.3,1.06,0.1,0.698,0.698,0.759,0,0,-1.5,1.1
ENSMUSG00000031146,PLP2,proteolipid protein 2,plasma membrane|extracellular vesicular exosome|,None,chemokine binding|,9,-0.1,0.442,9,0.2,1.28,0.2,0.693,0.693,0.76,0,0,-1.2,1.6
ENSMUSG00000023072,CEP89,centrosomal protein 89,spindle pole|cytoplasm|mitochondrion|centrosome|centriole|centriole|cytoskeleton|plasma membrane|ciliary transition fiber|,cell projection organization|cilium assembly|,protein binding|,10,0,0,10,0.3,1.21,0.2,0.677,0.677,0.763,0,0,-0.7,1.8
ENSMUSG00000014550,ZFYVE20,"zinc finger, FYVE domain containing 20",endosome|plasma membrane|membrane|intracellular membrane-bounded organelle|,transport|biological_process|protein transport|,Rab GTPase binding|metal ion binding|,10,0.3,0.599,10,1.1,1.97,0.3,0.673,0.673,0.764,0,0,-0.2,2
ENSMUSG00000040848,SFT2D2,SFT2 domain containing 2,membrane|integral component of membrane|extracellular vesicular exosome|,transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|,10,0.1,0.631,10,-0.2,0.833,0.5,0.67,0.67,0.765,0,0,-1,1.8
ENSMUSG00000058354,KRT6A,keratin 6A,intermediate filament|keratin filament|extracellular vesicular exosome|,morphogenesis of an epithelium|Wnt signaling pathway|keratinization|intermediate filament organization|,structural molecule activity|,10,-0.1,0.363,10,-0.3,0.543,-0.1,0.665,-0.665,0.765,0,0,-1.5,1.4
ENSMUSG00000028953,ABCF2,"ATP-binding cassette, sub-family F (GCN20), member 2",mitochondrion|membrane|,biological_process|,nucleotide binding|ATP binding|ATPase activity|,9,-0.1,0.481,9,-0.1,0.243,-0.1,0.663,-0.663,0.766,0,0,-1.5,1.4
ENSMUSG00000020061,MYBPC1,"myosin binding protein C, slow-type",cytoskeleton|,muscle contraction|,structural constituent of cytoskeleton|,10,0.2,0.916,10,0,0,0.1,0.663,0.663,0.766,0,0,-1.5,1.3
ENSMUSG00000006390,ELOVL1,"elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1",endoplasmic reticulum|membrane|membrane|integral component of membrane|,"lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation, saturated fatty acid|sphingolipid biosynthetic process|sphingolipid biosynthetic process|fatty acid elongation, monounsaturated fatty acid|very long-chain fatty acid biosynthetic process|",fatty acid elongase activity|transferase activity|,9,-0.1,0.349,9,-0.2,0.485,-0.1,0.662,-0.662,0.766,0,0,-1.7,1.2
ENSMUSG00000005803,SQRDL,sulfide quinone reductase-like (yeast),mitochondrion|mitochondrial inner membrane|,oxidation-reduction process|,N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.4,1.2,10,-0.1,0.0721,0.3,0.661,0.661,0.766,0,0,-0.8,1.8
ENSMUSG00000038298,PDZK1,PDZ domain containing 1,cytoplasm|plasma membrane|membrane|apical plasma membrane|brush border membrane|microvillus membrane|membrane raft|extracellular vesicular exosome|,transport|carnitine transport|positive regulation of ion transmembrane transport|regulation of anion transport|establishment of protein localization to plasma membrane|positive regulation of protein targeting to membrane|,scavenger receptor binding|protein binding|PDZ domain binding|protein complex binding|,10,-0.1,0.0711,10,0.5,1.81,0.1,0.66,0.66,0.767,0,0,-0.5,2
ENSMUSG00000032606,NICN1,nicolin 1,cellular_component|nucleus|microtubule|,biological_process|,molecular_function|,10,0.5,1.34,10,-0.2,0.919,0.1,0.658,0.658,0.767,0,0,-0.9,1.8
ENSMUSG00000021342,PRL,prolactin,extracellular region|secretory granule|secretory granule|,STAT protein import into nucleus|lactation|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of ossification|mammary gland development|maternal behavior|regulation of JAK-STAT cascade|positive regulation of JAK-STAT cascade|positive regulation of JAK-STAT cascade|positive regulation of epithelial cell proliferation|,prolactin receptor binding|hormone activity|,10,0,0,10,-0.2,0.722,-0.2,0.655,-0.655,0.768,0,0,-1.6,1.2
ENSMUSG00000036362,P2RY13,"purinergic receptor P2Y, G-protein coupled 13",endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|G-protein coupled purinergic nucleotide receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled purinergic nucleotide receptor activity|,10,-0.1,0.593,10,-0.1,0.119,-0.1,0.654,-0.654,0.768,0,0,-1.9,0.9
ENSMUSG00000045107,SAYSD1,SAYSVFN motif domain containing 1,membrane|integral component of membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|,biological_process|,molecular_function|,10,0.1,0.975,10,0,0,0.1,0.653,0.653,0.768,0,0,-1.1,1.6
ENSMUSG00000022783,SPAG6,sperm associated antigen 6,nucleus|cytoplasm|cytoskeleton|microtubule|cilium|microtubule cytoskeleton|cell projection|,spermatogenesis|cell projection organization|sperm motility|,protein binding|,10,0,0,10,0.2,1.2,0.1,0.636,0.636,0.772,0,0,-0.9,1.8
ENSMUSG00000036006,FAM65B,"family with sequence similarity 65, member B",cellular_component|,biological_process|,molecular_function|,10,-0.2,1.21,10,0.1,0.725,-0.1,0.626,-0.626,0.774,0,0,-1.5,1.1
ENSMUSG00000022559,FBXL6,F-box and leucine-rich repeat protein 6,cellular_component|,biological_process|,molecular_function|,10,0.1,0.28,10,0.3,0.932,0.2,0.623,0.623,0.774,0,0,-1.4,1.6
ENSMUSG00000026295,SPP2,secreted phosphoprotein 2,extracellular region|protein complex|extracellular vesicular exosome|,protein complex assembly|bone remodeling|,molecular_function|,10,0.1,0.0164,10,0.4,2.21,0.3,0.617,0.617,0.775,0,0,-0.8,1.7
ENSMUSG00000020935,DCAKD,dephospho-CoA kinase domain containing,mitochondrion|membrane|,biological_process|coenzyme A biosynthetic process|,nucleotide binding|molecular_function|dephospho-CoA kinase activity|ATP binding|,10,-0.1,0.0526,10,0.2,0.645,0.2,0.617,0.617,0.775,0,0,-1.1,1.6
ENSMUSG00000037196,PACRG,PARK2 co-regulated,nucleus|mitochondrion|cilium|cell body|sperm midpiece|,spermatid development|,molecular_function|,10,0.1,0.0297,10,0.3,0.929,0.2,0.613,0.613,0.776,0,0,-0.8,1.9
ENSMUSG00000021217,TSHZ3,teashirt zinc finger family member 3,nucleus|mitochondrion|growth cone|cell projection|,"ureteric bud development|in utero embryonic development|regulation of respiratory gaseous exchange by neurological system process|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|regulation of gene expression|lung development|negative regulation of transcription, DNA-templated|smooth muscle tissue development|musculoskeletal movement|sensory perception of touch|positive regulation of smooth muscle cell differentiation|kidney morphogenesis|ureteric peristalsis|ureter smooth muscle cell differentiation|kidney smooth muscle cell differentiation|",DNA binding|chromatin binding|protein binding|metal ion binding|,10,-0.3,2.12,10,0.1,0.856,-0.3,0.61,-0.61,0.777,0,0,-2,0.5
ENSMUSG00000022442,TTLL1,tubulin tyrosine ligase-like 1,cellular_component|cytoplasm|cytoskeleton|microtubule|,epithelial cilium movement|cellular protein modification process|protein polyglutamylation|axoneme assembly|cilium organization|cilium morphogenesis|,protein binding|ligase activity|,10,0.5,1.34,10,-0.3,1.86,-0.1,0.606,-0.606,0.778,0,0,-1,1.7
ENSMUSG00000032519,SLC25A38,"solute carrier family 25, member 38",cellular_component|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|erythrocyte differentiation|,molecular_function|,10,0.3,0.243,10,-0.3,1,-0.2,0.601,-0.601,0.779,0,0,-1.5,1.3
ENSMUSG00000031169,PORCN,porcupine homolog (Drosophila),endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,glycoprotein metabolic process|Wnt signaling pathway|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|protein binding|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.2,1.34,10,-0.8,2.26,0.1,0.601,0.601,0.779,0,0,-2,0.8
ENSMUSG00000020672,SNTG2,"syntrophin, gamma 2",cytoplasm|cytoskeleton|plasma membrane|membrane|,None,actin binding|PDZ domain binding|,10,0,0,10,-0.3,1.34,-0.1,0.6,-0.6,0.779,0,0,-1.8,0.9
ENSMUSG00000015095,FBXW5,F-box and WD-40 domain protein 5,cytoplasm|SCF ubiquitin ligase complex|SCF ubiquitin ligase complex|Cul4-RING E3 ubiquitin ligase complex|,mitotic nuclear division|protein ubiquitination|protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|centrosome duplication|,protein binding|protein kinase binding|,9,-0.2,0.402,9,-0.1,0.259,-0.2,0.593,-0.593,0.78,0,0,-1.8,0.9
ENSMUSG00000044348,SLC25A53,"solute carrier family 25, member 53",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,-0.2,1.12,10,0.3,0.251,-0.1,0.59,-0.59,0.781,0,0,-1.4,1.4
ENSMUSG00000037353,LETMD1,LETM1 domain containing 1,mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.582,10,0.1,0.0839,0.1,0.585,0.585,0.782,0,0,-1.2,1.6
ENSMUSG00000028700,POMGNT1,"protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase",Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|protein O-linked glycosylation|protein O-linked glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.1,0.43,10,0.2,0.39,0.1,0.584,0.584,0.782,0,0,-1,1.7
ENSMUSG00000037578,PKD2L1,polycystic kidney disease 2-like 1,endoplasmic reticulum|plasma membrane|plasma membrane|cilium|cell surface|membrane|integral component of membrane|nonmotile primary cilium|calcium channel complex|calcium channel complex|cell projection|intracellular membrane-bounded organelle|,detection of chemical stimulus involved in sensory perception of sour taste|transport|ion transport|cation transport|cation transport|calcium ion transport|smoothened signaling pathway|ion transmembrane transport|sodium ion transmembrane transport|sensory perception of sour taste|detection of mechanical stimulus|protein homotrimerization|calcium ion transmembrane transport|cellular response to acidity|potassium ion transmembrane transport|,calcium activated cation channel activity|cation channel activity|cation channel activity|cation channel activity|calcium channel activity|calcium channel activity|calcium channel activity|sodium channel activity|calcium ion binding|calcium ion binding|protein binding|cytoskeletal protein binding|cation transmembrane transporter activity|calcium-activated potassium channel activity|sour taste receptor activity|identical protein binding|muscle alpha-actinin binding|alpha-actinin binding|,10,0,0,10,-0.3,1.33,-0.2,0.58,-0.58,0.783,0,0,-1.8,0.8
ENSMUSG00000015659,SERAC1,serine active site containing 1,nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|extracellular matrix|,GPI anchor metabolic process|lipid metabolic process|intracellular protein transport|phospholipid biosynthetic process|extracellular matrix organization|,"hydrolase activity, acting on ester bonds|",10,0.2,0.826,10,0.1,0.274,0.2,0.579,0.579,0.783,0,0,-1.1,1.6
ENSMUSG00000050705,2310061I04RIK,RIKEN cDNA 2310061I04 gene,mitochondrion|,biological_process|,molecular_function|,10,0.1,0.0594,10,-0.4,1.18,-0.1,0.573,-0.573,0.784,0,0,-1.5,1.2
ENSMUSG00000023861,MPC1,mitochondrial pyruvate carrier 1,intracellular|cell|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,pyruvate metabolic process|transport|mitochondrial pyruvate transport|,pyruvate transmembrane transporter activity|,10,0,0,10,-0.3,0.963,-0.3,0.57,-0.57,0.785,0,0,-1.4,1.4
ENSMUSG00000020375,RUFY1,RUN and FYVE domain containing 1,nucleus|cytoplasm|cytoplasm|endosome|membrane|intracellular membrane-bounded organelle|,transport|endocytosis|protein transport|regulation of endocytosis|,protein binding|lipid binding|protein transporter activity|metal ion binding|,10,0.3,0.809,10,-0.2,0.468,-0.1,0.565,-0.565,0.786,0,0,-1.4,1.4
ENSMUSG00000028354,FMN2,formin 2,intracellular|cell|nucleus|nucleolus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|spindle|cytosol|cytoskeleton|actin filament|plasma membrane|microvillus|cell cortex|actin cytoskeleton|membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle|,transport|response to stress|cellular response to DNA damage stimulus|multicellular organismal development|protein transport|vesicle-mediated transport|meiotic chromosome movement towards spindle pole|polar body extrusion after meiotic divisions|negative regulation of protein catabolic process|negative regulation of apoptotic process|actin nucleation|intracellular transport|oogenesis|actin filament bundle assembly|establishment of meiotic spindle localization|homologous chromosome movement towards spindle pole involved in homologous chromosome segregation|formin-nucleated actin cable assembly|cellular response to hypoxia|,actin binding|,10,0.1,0.283,10,-0.3,1.46,-0.1,0.565,-0.565,0.786,0,0,-1.5,1.2
ENSMUSG00000030279,C2CD5,C2 calcium-dependent domain containing 5,cytoplasm|plasma membrane|plasma membrane|cell cortex|membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle|ruffle membrane|cell projection|,transport|vesicle fusion|positive regulation of glucose transport|protein transport|positive regulation of vesicle fusion|positive regulation of vesicle fusion|cellular response to insulin stimulus|cellular response to insulin stimulus|insulin receptor signaling pathway via phosphatidylinositol 3-kinase|intracellular protein transmembrane transport|protein localization to plasma membrane|protein localization to plasma membrane|positive regulation of protein targeting to membrane|positive regulation of glucose import in response to insulin stimulus|positive regulation of glucose import in response to insulin stimulus|,calcium ion binding|calcium ion binding|calcium-dependent phospholipid binding|lipid binding|,10,0.1,0.39,10,0.4,1.05,0.1,0.563,0.563,0.786,0,0,-0.9,1.8
ENSMUSG00000026589,SEC16B,SEC16 homolog B (S. cerevisiae),endoplasmic reticulum|Golgi apparatus|membrane|intracellular membrane-bounded organelle|,transport|endoplasmic reticulum organization|peroxisome organization|positive regulation of gene expression|protein transport|vesicle-mediated transport|peroxisome fission|COPII vesicle coating|positive regulation of protein exit from endoplasmic reticulum|protein localization to endoplasmic reticulum|,molecular_function|,10,-0.2,1.48,10,0.4,1.93,0.3,0.562,0.562,0.787,0,0,-1.2,1.5
ENSMUSG00000027935,RAB13,"RAB13, member RAS oncogene family",intracellular|cell|cytoplasm|endosome|Golgi apparatus|trans-Golgi network|plasma membrane|cell-cell junction|tight junction|tight junction|membrane|cytoplasmic membrane-bounded vesicle|lateral plasma membrane|extrinsic component of plasma membrane|lamellipodium|cell junction|endocytic vesicle|endocytic vesicle|cytoplasmic vesicle|insulin-responsive compartment|cell projection|neuron projection|recycling endosome|extracellular vesicular exosome|,GTP catabolic process|GTP catabolic process|transport|intracellular protein transport|small GTPase mediated signal transduction|protein kinase A signaling|protein transport|endosomal transport|cortical actin cytoskeleton organization|neuron projection development|endocytic recycling|endocytic recycling|cellular response to insulin stimulus|endothelial cell chemotaxis|tight junction assembly|protein localization to plasma membrane|establishment of protein localization to plasma membrane|establishment of Sertoli cell barrier|protein localization to cell leading edge|,nucleotide binding|GTPase activity|GTPase activity|GTP binding|protein kinase A catalytic subunit binding|,10,0.1,0.182,10,0.4,1.64,0.1,0.561,0.561,0.787,0,0,-0.8,1.7
ENSMUSG00000020641,RSAD2,radical S-adenosyl methionine domain containing 2,mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|endoplasmic reticulum|endoplasmic reticulum membrane|lipid particle|membrane|,"ossification|immune system process|response to virus|response to virus|regulation of ossification|positive regulation of toll-like receptor 7 signaling pathway|positive regulation of toll-like receptor 9 signaling pathway|CD4-positive, alpha-beta T cell activation|CD4-positive, alpha-beta T cell differentiation|negative regulation of viral genome replication|negative regulation of viral genome replication|innate immune response|negative regulation of protein secretion|defense response to virus|defense response to virus|positive regulation of T-helper 2 cell cytokine production|","catalytic activity|protein binding|protein self-association|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.1,0.262,10,0.6,0.586,0.1,0.558,0.558,0.787,0,0,-0.9,1.9
ENSMUSG00000066892,FBXL12,F-box and leucine-rich repeat protein 12,ubiquitin ligase complex|cytoplasm|,ubiquitin-dependent protein catabolic process|,molecular_function|,10,0.1,0.156,10,0.3,1.02,0.2,0.554,0.554,0.788,0,0,-0.9,1.7
ENSMUSG00000025647,SHISA5,shisa family member 5,intracellular|nucleus|nuclear envelope|endoplasmic reticulum|membrane|integral component of membrane|extracellular vesicular exosome|,apoptotic process|signal transduction|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of I-kappaB kinase/NF-kappaB signaling|intrinsic apoptotic signaling pathway by p53 class mediator|,signal transducer activity|WW domain binding|,10,0.1,0.991,10,0,0,0.1,0.553,0.553,0.788,0,0,-0.7,2
ENSMUSG00000033579,FA2H,fatty acid 2-hydroxylase,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,sebaceous gland cell differentiation|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|sphingolipid metabolic process|transport|lipid modification|lipid modification|central nervous system myelin maintenance|peripheral nervous system myelin maintenance|regulation of cell proliferation|regulation of hair cycle|oxidation-reduction process|,iron ion binding|N-ethylmaleimide reductase activity|oxidoreductase activity|heme binding|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|epoxyqueuosine reductase activity|fatty acid alpha-hydroxylase activity|,10,0.1,0.106,10,0.4,0.892,0.5,0.551,0.551,0.789,0,0,-0.6,1.8
ENSMUSG00000028524,SGIP1,SH3-domain GRB2-like (endophilin) interacting protein 1,cytoplasm|plasma membrane|plasma membrane|coated pit|membrane|AP-2 adaptor complex|clathrin-coated vesicle|,response to dietary excess|endocytosis|positive regulation of receptor-mediated endocytosis|membrane tubulation|positive regulation of feeding behavior|positive regulation of energy homeostasis|,protein binding|phospholipid binding|microtubule binding|tubulin binding|tubulin binding|SH3 domain binding|,10,-0.4,0.681,10,0.1,0.369,-0.2,0.548,-0.548,0.789,0,0,-1.8,0.8
ENSMUSG00000061816,MYL1,"myosin, light polypeptide 1",myosin complex|myofibril|contractile fiber|,muscle contraction|cardiac muscle contraction|,calcium ion binding|,10,0.1,1.04,10,1.2,0.378,0.1,0.548,0.548,0.789,0,0,-0.6,2
ENSMUSG00000084128,ESRP2,epithelial splicing regulatory protein 2,nucleus|,mRNA processing|RNA splicing|regulation of RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|poly(A) RNA binding|,10,-0.2,1.7,10,0,0,-0.2,0.543,-0.543,0.79,0,0,-1.3,1.3
ENSMUSG00000026657,FRMD4A,FERM domain containing 4A,cytoplasm|cytoskeleton|tight junction|,establishment of epithelial cell polarity|,"protein binding, bridging|",10,-0.6,2.02,10,0.9,0.564,-0.1,0.531,-0.531,0.793,0,0,-1.9,1.3
ENSMUSG00000059288,CDYL,"chromodomain protein, Y chromosome-like",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|metabolic process|regulation of RNA biosynthetic process|","transcription corepressor activity|catalytic activity|histone acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.5,0.828,10,-0.1,0.0572,-0.2,0.523,-0.523,0.795,0,0,-1.7,1
ENSMUSG00000050270,TMEM220,transmembrane protein 220,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.3,1.27,9,0,0,-0.2,0.521,-0.521,0.795,0,0,-1.6,1.2
ENSMUSG00000055926,GM14137,predicted gene 14137,cellular_component|mitochondrion|,biological_process|,molecular_function|,10,0,0,10,0.3,1.84,0.2,0.516,0.516,0.796,0,0,-0.9,1.8
ENSMUSG00000030652,COQ7,demethyl-Q 7,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,age-dependent response to oxidative stress|in utero embryonic development|neural tube formation|ubiquinone biosynthetic process|response to oxidative stress|response to oxidative stress|determination of adult lifespan|neurogenesis|respiratory electron transport chain|cellular response to oxidative stress|mitochondrial ATP synthesis coupled electron transport|oxidation-reduction process|mitochondrion morphogenesis|,metal ion binding|,10,-0.1,0.35,10,-0.1,0.209,-0.1,0.511,-0.511,0.797,0,0,-1.9,0.9
ENSMUSG00000025129,PPP1R27,"protein phosphatase 1, regulatory subunit 27",cellular_component|,negative regulation of phosphatase activity|,protein phosphatase inhibitor activity|phosphatase binding|,10,-0.2,0.31,10,-0.3,0.276,-0.2,0.509,-0.509,0.798,0,0,-1.7,1
ENSMUSG00000027861,CASQ2,calsequestrin 2,intracellular|cytoplasm|sarcoplasmic reticulum|sarcoplasmic reticulum|Z disc|Z disc|,regulation of heart rate|regulation of muscle contraction|regulation of cell communication by electrical coupling|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|negative regulation of potassium ion transport|sequestering of calcium ion|protein polymerization|cardiac muscle contraction|regulation of membrane repolarization|negative regulation of ryanodine-sensitive calcium-release channel activity|cellular response to caffeine|regulation of cardiac muscle cell contraction|negative regulation of potassium ion transmembrane transporter activity|,protein kinase C binding|calcium ion binding|protein homodimerization activity|,10,0,0,10,-0.5,2.24,-0.1,0.504,-0.504,0.799,0,0,-1.6,1.4
ENSMUSG00000045094,ARHGEF37,Rho guanine nucleotide exchange factor (GEF) 37,cellular_component|cytoplasm|,biological_process|regulation of Rho protein signal transduction|,molecular_function|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0.2,0.219,10,0.2,0.323,0.2,0.496,0.496,0.8,0,0,-1.1,1.6
ENSMUSG00000022946,DOPEY2,dopey family member 2,extracellular vesicular exosome|,transport|protein transport|cognition|,molecular_function|,10,0.8,1.89,10,0,0,0.2,0.494,0.494,0.801,0,0,-0.4,2
ENSMUSG00000028249,SDCBP,syndecan binding protein,extracellular space|intracellular|cytoplasm|plasma membrane|interleukin-5 receptor complex|membrane|extracellular vesicular exosome|blood microparticle|,Ras protein signal transduction|positive regulation of phosphorylation|,glycoprotein binding|frizzled binding|interleukin-5 receptor binding|protein binding|protein C-terminus binding|growth factor binding|neurexin family protein binding|identical protein binding|protein homodimerization activity|syndecan binding|ephrin receptor binding|protein heterodimerization activity|protein N-terminus binding|cell adhesion molecule binding|,10,-0.2,1.3,10,0.1,0.00681,-0.1,0.487,-0.487,0.802,0,0,-1.4,1.3
ENSMUSG00000074577,FAM65C,"family with sequence similarity 65, member C",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.7,3.6,-0.6,0.484,-0.484,0.803,0,0,-2,0.3
ENSMUSG00000024376,EPB4.1L4A,erythrocyte protein band 4.1-like 4a,cytoplasm|cytoskeleton|extrinsic component of membrane|,None,cytoskeletal protein binding|,10,-0.1,0.252,10,1.1,0.747,-0.1,0.481,-0.481,0.803,0,0,-1,2
ENSMUSG00000062773,TEX101,testis expressed gene 101,acrosomal membrane|plasma membrane|membrane|anchored component of membrane|membrane raft|,positive regulation of leukocyte activation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of release of sequestered calcium ion into cytosol|,None,10,0.2,0.355,10,0.2,0.17,0.2,0.479,0.479,0.804,0,0,-0.9,1.8
ENSMUSG00000058587,TMOD3,tropomodulin 3,ruffle|cytoplasm|cytoskeleton|striated muscle thin filament|lamellipodium|filamentous actin|,negative regulation of cellular component movement|pointed-end actin filament capping|,actin binding|tropomyosin binding|microtubule minus-end binding|,10,0.3,1.16,10,0.1,0.0901,0.2,0.476,0.476,0.804,0,0,-1.1,1.7
ENSMUSG00000024997,PRDX3,peroxiredoxin 3,cytoplasm|mitochondrion|mitochondrion|early endosome|cytosol|IkappaB kinase complex|extracellular vesicular exosome|,maternal placenta development|response to oxidative stress|response to oxidative stress|mitochondrion organization|positive regulation of cell proliferation|peptidyl-cysteine oxidation|myeloid cell differentiation|response to lipopolysaccharide|negative regulation of kinase activity|cellular response to oxidative stress|cellular response to reactive oxygen species|response to hydrogen peroxide|hydrogen peroxide catabolic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of neuron apoptotic process|positive regulation of NF-kappaB transcription factor activity|regulation of mitochondrial membrane potential|oxidation-reduction process|,peroxidase activity|protein C-terminus binding|thioredoxin peroxidase activity|antioxidant activity|oxidoreductase activity|kinase binding|protein kinase binding|identical protein binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|peroxiredoxin activity|,10,0.1,1.2,10,-0.4,0.999,0.1,0.472,0.472,0.805,0,0,-1.7,0.9
ENSMUSG00000008090,FGFRL1,fibroblast growth factor receptor-like 1,plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,skeletal system development|heart valve morphogenesis|cell surface receptor signaling pathway|negative regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|peptidyl-tyrosine phosphorylation|negative regulation of fibroblast growth factor receptor signaling pathway|ventricular septum morphogenesis|diaphragm development|,non-tyrosine kinase fibroblast growth factor receptor activity|fibroblast growth factor-activated receptor activity|fibroblast growth factor-activated receptor activity|heparin binding|fibroblast growth factor binding|,10,0.1,0.272,10,-0.2,0.955,0.1,0.47,0.47,0.805,0,0,-1.4,1.4
ENSMUSG00000029015,SLC26A5,"solute carrier family 26, member 5",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|lateral plasma membrane|lateral plasma membrane|,sensory perception of sound|sulfate transport|regulation of cell shape|regulation of membrane potential|transmembrane transport|,protein binding|secondary active sulfate transmembrane transporter activity|sulfate transmembrane transporter activity|spectrin binding|,10,0.1,0.231,10,0.1,0.283,0.1,0.469,0.469,0.806,0,0,-1.2,1.6
ENSMUSG00000000223,DRP2,dystrophin related protein 2,cytoplasm|cytoskeleton|plasma membrane|membrane|dendrite|,synapse organization|,calcium ion binding|protein binding|zinc ion binding|metal ion binding|,10,-0.2,0.495,10,1.1,1.83,-0.1,0.469,-0.469,0.806,0,0,-0.7,2
ENSMUSG00000079043,FASTKD5,FAST kinase domains 5,mitochondrion|mitochondrion|,cellular respiration|,protein kinase activity|poly(A) RNA binding|,10,0.2,0.908,10,0,0,0.1,0.461,0.461,0.808,0,0,-1,1.7
ENSMUSG00000026036,NIF3L1,Ngg1 interacting factor 3-like 1 (S. pombe),cytoplasm|cytoplasm|mitochondrion|,"positive regulation of transcription, DNA-templated|",nucleotide binding|GTP cyclohydrolase I activity|GTP binding|transcription factor binding|hydrolase activity|metal ion binding|,10,0.3,2.05,10,-0.3,1.49,0.2,0.449,0.449,0.81,0,0,-1.3,1.5
ENSMUSG00000028145,THEM4,thioesterase superfamily member 4,cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|cytosol|plasma membrane|membrane|cell projection|,lipid metabolic process|fatty acid metabolic process|apoptotic process|viral process|protein kinase B signaling|regulation of mitochondrial membrane permeability involved in apoptotic process|,palmitoyl-CoA hydrolase activity|hydrolase activity|,10,-0.7,2.25,10,0.6,1.88,0.2,0.443,0.443,0.811,0,0,-1.8,1.3
ENSMUSG00000042985,UPK3B,uroplakin 3B,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,negative regulation of gene expression|,None,10,-0.3,0.551,10,-0.1,0.0378,-0.2,0.439,-0.439,0.812,0,0,-1.7,1.2
ENSMUSG00000029007,AGTRAP,"angiotensin II, type I receptor-associated protein",endoplasmic reticulum|Golgi apparatus|plasma membrane|cell cortex|membrane|integral component of membrane|cytoplasmic vesicle|,regulation of blood pressure|angiotensin-activated signaling pathway|,angiotensin type II receptor activity|protein binding|,10,0.1,0.52,10,-0.1,0.173,0.1,0.432,0.432,0.813,0,0,-1.2,1.5
ENSMUSG00000023791,PIGX,"phosphatidylinositol glycan anchor biosynthesis, class X",cellular_component|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|,molecular_function|,10,-0.1,0.647,10,0,0,-0.1,0.421,-0.421,0.816,0,0,-1.8,1.1
ENSMUSG00000022090,PDLIM2,PDZ and LIM domain 2,stress fiber|cytoplasm|cytoskeleton|focal adhesion|actin cytoskeleton|cortical actin cytoskeleton|extracellular vesicular exosome|,None,zinc ion binding|filamin binding|myosin heavy chain binding|metal ion binding|muscle alpha-actinin binding|alpha-actinin binding|,10,-0.2,0.583,10,-0.1,0.0813,-0.2,0.421,-0.421,0.816,0,0,-1.6,1.2
ENSMUSG00000073678,PGAP1,post-GPI attachment to proteins 1,endoplasmic reticulum|membrane|integral component of membrane|,GPI anchor metabolic process|GPI anchor biosynthetic process|transport|intracellular protein transport|sensory perception of sound|embryonic pattern specification|embryonic pattern specification|anterior/posterior axis specification|anterior/posterior axis specification|protein transport|myo-inositol transport|forebrain regionalization|forebrain regionalization|head development|head development|nucleic acid phosphodiester bond hydrolysis|,"nuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|",10,-0.2,1.31,10,0,0,-0.1,0.419,-0.419,0.816,0,0,-1.5,1.4
ENSMUSG00000031214,OPHN1,oligophrenin 1,intracellular|cell|cytoplasm|actin cytoskeleton|cell junction|dendrite|cell projection|terminal bouton|dendritic spine|synapse|,"endocytosis|signal transduction|nervous system development|actin cytoskeleton organization|regulation of endocytosis|positive regulation of Rho GTPase activity|synaptic vesicle endocytosis|synaptic vesicle endocytosis|regulation of synaptic transmission, glutamatergic|negative regulation of proteasomal protein catabolic process|",actin binding|GTPase activator activity|Rho GTPase activator activity|protein binding|phospholipid binding|ionotropic glutamate receptor binding|,10,-0.4,0.42,10,0.1,0.551,0.1,0.417,0.417,0.816,0,0,-1.8,0.9
ENSMUSG00000021294,KIF26A,kinesin family member 26A,cytoplasm|cytoskeleton|kinesin complex|microtubule|,regulation of cell growth by extracellular stimulus|negative regulation of signal transduction|enteric nervous system development|,nucleotide binding|protein binding|ATP binding|microtubule binding|,10,0.2,1.35,10,-0.1,0.15,0.1,0.4,0.4,0.82,0,0,-1.2,1.6
ENSMUSG00000019906,LIN7A,lin-7 homolog A (C. elegans),cell|plasma membrane|tight junction|membrane|basolateral plasma membrane|cell junction|neuron projection|synapse|postsynaptic membrane|extracellular vesicular exosome|,transport|exocytosis|neurotransmitter secretion|protein transport|synaptic vesicle transport|inner ear development|,protein binding|L27 domain binding|,10,0.7,0.173,10,0.1,0.538,0.1,0.4,0.4,0.82,0,0,-0.6,2
ENSMUSG00000043257,PIGV,"phosphatidylinositol glycan anchor biosynthesis, class V",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|mannosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,-0.3,1.72,-0.1,0.394,-0.394,0.821,0,0,-1.8,0.9
ENSMUSG00000054453,SYTL5,synaptotagmin-like 5,cell|membrane|,intracellular protein transport|exocytosis|,protein binding|Rab GTPase binding|metal ion binding|,10,-0.2,1.06,10,0,0,-0.1,0.386,-0.386,0.823,0,0,-1.7,1.1
ENSMUSG00000054545,UGT1A6A,"UDP glucuronosyltransferase 1 family, polypeptide A6A",mitochondrial inner membrane|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|protein complex|extracellular vesicular exosome|,metabolic process|glucuronate metabolic process|glucuronate metabolic process|,"glucuronosyltransferase activity|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|enzyme binding|protein complex binding|protein homodimerization activity|protein heterodimerization activity|",10,-0.1,0.234,10,0.4,1.58,-0.1,0.383,-0.383,0.824,0,0,-0.9,1.8
ENSMUSG00000091712,SEC14L5,SEC14-like 5 (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,-0.1,0.15,10,-0.2,0.336,-0.1,0.383,-0.383,0.824,0,0,-1.8,0.9
ENSMUSG00000024570,RBFA,ribosome binding factor A,cellular_component|mitochondrion|,rRNA processing|,molecular_function|,10,-0.1,0.817,10,0.1,0.0481,-0.1,0.382,-0.382,0.824,0,0,-1.3,1.5
ENSMUSG00000030982,9030624J02RIK,RIKEN cDNA 9030624J02 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.388,10,-0.1,0.0486,-0.1,0.38,-0.38,0.824,0,0,-1.6,1.4
ENSMUSG00000015733,CAPZA2,"capping protein (actin filament) muscle Z-line, alpha 2",F-actin capping protein complex|membrane|cortical cytoskeleton|extracellular vesicular exosome|WASH complex|,biological_process|actin cytoskeleton organization|actin filament capping|,actin binding|protein binding|,10,0.1,0.285,10,0.1,0.129,0.1,0.378,0.378,0.825,0,0,-1,1.9
ENSMUSG00000021228,ACOT3,acyl-CoA thioesterase 3,peroxisome|cytosol|cytosol|,very long-chain fatty acid metabolic process|very long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|acyl-CoA metabolic process|acyl-CoA metabolic process|saturated monocarboxylic acid metabolic process|unsaturated monocarboxylic acid metabolic process|,palmitoyl-CoA hydrolase activity|hydrolase activity|thiolester hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|,10,-0.1,0.153,10,0.4,1.78,0.4,0.37,0.37,0.826,0,0,-0.7,1.9
ENSMUSG00000038181,CHPF2,chondroitin polymerizing factor 2,membrane|,biological_process|,molecular_function|,10,0.1,0.614,10,0,0,0.1,0.37,0.37,0.826,0,0,-1.3,1.4
ENSMUSG00000056671,PRELID2,PRELI domain containing 2,mitochondrion|mitochondrial intermembrane space|,phospholipid transport|,phosphatidic acid transporter activity|,10,0.2,0.498,10,0.1,0.185,0.2,0.369,0.369,0.827,0,0,-1.1,1.6
ENSMUSG00000017311,PYY,peptide YY,extracellular region|extracellular space|extracellular space|,negative regulation of response to food|eating behavior|,hormone activity|neuropeptide hormone activity|,10,0.2,0.149,10,0.1,0.271,0.1,0.367,0.367,0.827,0,0,-1.3,1.5
ENSMUSG00000028222,CALB1,calbindin 1,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|axon|axon|dendrite|dendrite|neuron projection|neuronal cell body|neuronal cell body|cell body|synapse|extracellular vesicular exosome|,short-term memory|long-term memory|locomotory behavior|regulation of synaptic plasticity|cytosolic calcium ion homeostasis|cellular response to organic substance|,vitamin D binding|calcium ion binding|zinc ion binding|metal ion binding|,10,0.7,1.62,10,-0.1,0.165,-0.1,0.36,-0.36,0.829,0,0,-0.7,2
ENSMUSG00000001588,ACAP1,"ArfGAP with coiled-coil, ankyrin repeat and PH domains 1",endosome|membrane|membrane|,lipid metabolic process|signal transduction|biological_process|lipid catabolic process|regulation of ARF GTPase activity|,molecular_function|signal transducer activity|ARF GTPase activator activity|zinc ion binding|hydrolase activity|metal ion binding|,9,-0.4,0.381,9,0.2,0.604,-0.3,0.359,-0.359,0.829,0,0,-1.7,1.2
ENSMUSG00000022788,FGD4,"FYVE, RhoGEF and PH domain containing 4",cytoplasm|cytoskeleton|actin cytoskeleton|lamellipodium|filopodium|cell projection|,activation of JUN kinase activity|regulation of cell shape|lamellipodium assembly|microspike assembly|regulation of Rho protein signal transduction|,actin binding|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|metal ion binding|actin filament binding|,10,0.1,0.55,10,0,0,0.1,0.356,0.356,0.83,0,0,-1.3,1.6
ENSMUSG00000026304,RAB17,"RAB17, member RAS oncogene family",intracellular|intracellular|cell|endosome|membrane|basolateral plasma membrane|apical plasma membrane|dendrite|melanosome|cell projection|neuronal cell body|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|,immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor|transport|small GTPase mediated signal transduction|protein transport|establishment of melanosome localization|melanosome transport|endocytic recycling|transcytosis|filopodium assembly|regulation of dendrite development|regulation of filopodium assembly|regulation of synapse assembly|,nucleotide binding|protein binding|GTP binding|GDP binding|,10,-0.1,0.811,10,0.1,0.51,0.1,0.356,0.356,0.83,0,0,-1.3,1.5
ENSMUSG00000040706,AGMAT,agmatine ureohydrolase (agmatinase),mitochondrion|extracellular vesicular exosome|,biological_process|spermidine biosynthetic process|putrescine biosynthetic process|,molecular_function|agmatinase activity|hydrolase activity|metal ion binding|,10,0,0,10,0.4,1.79,0.1,0.355,0.355,0.83,0,0,-0.8,1.9
ENSMUSG00000051346,SPRYD4,SPRY domain containing 4,nucleus|mitochondrion|,biological_process|,molecular_function|,10,-0.2,0.872,10,0,0,-0.1,0.344,-0.344,0.832,0,0,-1.6,1.2
ENSMUSG00000013997,NIT1,nitrilase 1,nucleus|cytoplasm|mitochondrion|extracellular vesicular exosome|,nitrogen compound metabolic process|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|",10,-0.1,0.187,10,-0.2,0.211,-0.1,0.342,-0.342,0.833,0,0,-1.7,1.1
ENSMUSG00000031093,DOCK11,dedicator of cytokinesis 11,cellular_component|,small GTPase mediated signal transduction|positive regulation of Rho GTPase activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho GTPase binding|,10,-0.7,1.93,10,0,0,-0.1,0.336,-0.336,0.834,0,0,-2,0.4
ENSMUSG00000062694,CAV3,caveolin 3,cytoplasm|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|caveola|caveola|caveola|cell surface|intercalated disc|dystrophin-associated glycoprotein complex|membrane|Z disc|T-tubule|T-tubule|neuromuscular junction|vesicle|sarcolemma|sarcolemma|sarcolemma|protein complex|membrane raft|,plasma membrane repair|regulation of heart rate|negative regulation of protein kinase activity|triglyceride metabolic process|endocytosis|endocytosis|plasma membrane organization|actin filament organization|positive regulation of cytosolic calcium ion concentration|myoblast fusion|regulation of heart contraction|protein localization|protein localization|positive regulation of cell proliferation|negative regulation of cardiac muscle hypertrophy|negative regulation of cardiac muscle hypertrophy|positive regulation of myotube differentiation|regulation of skeletal muscle contraction|myotube differentiation|regulation of transforming growth factor beta receptor signaling pathway|positive regulation of microtubule polymerization|cytoplasmic microtubule organization|membrane raft organization|regulation of signal transduction by receptor internalization|regulation of membrane potential|regulation of membrane potential|glucose homeostasis|cholesterol homeostasis|negative regulation of MAP kinase activity|negative regulation of MAPK cascade|negative regulation of cell size|muscle cell cellular homeostasis|negative regulation of nitric-oxide synthase activity|regulation of nerve growth factor receptor activity|nucleus localization|regulation of protein kinase B signaling|regulation of calcium ion transport|negative regulation of calcium ion transport|negative regulation of calcium ion transport|cardiac muscle cell development|regulation of cardiac muscle contraction|negative regulation of sarcomere organization|regulation of ventricular cardiac muscle cell membrane repolarization|heart trabecula formation|regulation of ventricular cardiac muscle cell membrane depolarization|regulation of branching involved in mammary gland duct morphogenesis|negative regulation of cell growth involved in cardiac muscle cell development|caveola assembly|caveola assembly|protein localization to plasma membrane|ventricular cardiac muscle cell action potential|establishment of protein localization to plasma membrane|regulation of calcium ion import|regulation of p38MAPK cascade|regulation of membrane depolarization during cardiac muscle cell action potential|negative regulation of potassium ion transmembrane transporter activity|regulation of calcium ion transmembrane transporter activity|negative regulation of potassium ion transmembrane transport|regulation of sodium ion transmembrane transporter activity|positive regulation of caveolin-mediated endocytosis|,calcium channel regulator activity|protein binding|protein C-terminus binding|sodium channel regulator activity|potassium channel inhibitor activity|enzyme binding|protein complex binding|protein complex scaffold|alpha-tubulin binding|ion channel binding|ion channel binding|nitric-oxide synthase binding|connexin binding|connexin binding|,10,0.1,0.744,10,0,0,0.1,0.327,0.327,0.836,0,0,-1.1,1.8
ENSMUSG00000021892,SH3BP5,SH3-domain binding protein 5 (BTK-associated),cytoplasm|mitochondrion|,negative regulation of protein kinase activity|negative regulation of protein kinase activity|intracellular signal transduction|,protein kinase inhibitor activity|SH3 domain binding|,10,0.1,0.499,10,0,0,0.1,0.323,0.323,0.836,0,0,-1,1.9
ENSMUSG00000029260,UGT2B34,"UDP glucuronosyltransferase 2 family, polypeptide B34",cellular_component|,biological_process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|",10,0.3,1.7,10,-0.2,0.428,0.2,0.32,0.32,0.837,0,0,-1.3,1.4
ENSMUSG00000032033,BARX2,BarH-like homeobox 2,nucleus|transcription factor complex|mitochondrion|,"negative regulation of transcription from RNA polymerase II promoter|cartilage condensation|cartilage condensation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|myotube differentiation|catagen|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.2,1.1,10,0.2,0.564,-0.1,0.319,-0.319,0.837,0,0,-1.5,1.3
ENSMUSG00000042707,DNALI1,"dynein, axonemal, light intermediate polypeptide 1",cytoplasm|cytoplasm|axonemal dynein complex|axoneme|axoneme|filopodium|dynein complex|,cilium movement|,motor activity|dynein heavy chain binding|,10,0.1,0.512,10,0,0,0.1,0.319,0.319,0.837,0,0,-0.7,2
ENSMUSG00000021930,SPRYD7,SPRY domain containing 7,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.34,10,0.2,0.746,0.1,0.316,0.316,0.838,0,0,-1.7,1.1
ENSMUSG00000031991,SPATA19,spermatogenesis associated 19,cellular_component|mitochondrion|mitochondrial outer membrane|membrane|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,0.4,1.82,10,-0.5,2.45,0.1,0.311,0.311,0.839,0,0,-1.7,1.2
ENSMUSG00000031860,PBX4,pre B cell leukemia homeobox 4,XY body|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.2,0.56,10,0,0,0.2,0.31,0.31,0.839,0,0,-1.2,1.6
ENSMUSG00000035517,TDRD7,tudor domain containing 7,cytoplasm|mitochondrial matrix|ribonucleoprotein complex|chromatoid body|ribonucleoprotein granule|P granule|,lens morphogenesis in camera-type eye|lens morphogenesis in camera-type eye|multicellular organismal development|germ cell development|spermatogenesis|posttranscriptional regulation of gene expression|cell differentiation|lens fiber cell differentiation|lens fiber cell differentiation|,RNA binding|mRNA binding|protein binding|protein N-terminus binding|,10,0.1,0.491,10,0,0,0.1,0.309,0.309,0.839,0,0,-1,1.8
ENSMUSG00000026494,KIF26B,kinesin family member 26B,cytoplasm|cytoskeleton|kinesin complex|microtubule|,microtubule-based movement|multicellular organismal development|positive regulation of cell-cell adhesion|positive regulation of cell-cell adhesion|establishment of cell polarity|ureteric bud invasion|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,0.8,1.08,10,0.2,0.221,0.1,0.308,0.308,0.839,0,0,-0.7,2
ENSMUSG00000071311,GPR31B,"G protein-coupled receptor 31, D17Leh66b region",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0.3,1.06,0.1,0.308,0.308,0.839,0,0,-1,1.8
ENSMUSG00000054423,CADPS,Ca2+-dependent secretion activator,cell|membrane|cell junction|cytoplasmic vesicle|synapse|,transport|protein transport|vesicle organization|synaptic vesicle priming|positive regulation of calcium ion-dependent exocytosis|catecholamine secretion|,calcium ion binding|protein binding|lipid binding|metal ion binding|,10,-0.3,0.828,10,0,0,-0.3,0.306,-0.306,0.84,0,0,-1.7,1
ENSMUSG00000038844,KIF16B,kinesin family member 16B,intracellular|cell|cytoplasm|endosome|early endosome|cytoskeleton|kinesin complex|microtubule|membrane|,formation of primary germ layer|regulation of receptor recycling|transport|Golgi to endosome transport|microtubule-based movement|epidermal growth factor receptor signaling pathway|endoderm development|fibroblast growth factor receptor signaling pathway|receptor catabolic process|early endosome to late endosome transport|,"nucleotide binding|microtubule motor activity|ATP binding|phosphatidylinositol-3,4,5-trisphosphate binding|microtubule binding|lipid binding|plus-end-directed microtubule motor activity|Rab GTPase binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol binding|phosphatidylinositol-3,4-bisphosphate binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0,0,10,0.4,1.63,0.1,0.304,0.304,0.84,0,0,-0.9,1.8
ENSMUSG00000001844,ZDHHC4,"zinc finger, DHHC domain containing 4",Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|zinc ion binding|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.7,0.339,10,0.1,0.424,0.1,0.296,0.296,0.842,0,0,-0.6,2
ENSMUSG00000061584,LYG2,lysozyme G-like 2,cellular_component|extracellular region|,biological_process|metabolic process|peptidoglycan catabolic process|cell wall macromolecule catabolic process|,"molecular_function|lysozyme activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,-0.1,0.379,10,0.1,0.223,0.1,0.283,0.283,0.845,0,0,-1.1,1.7
ENSMUSG00000026170,CYP27A1,"cytochrome P450, family 27, subfamily a, polypeptide 1",mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial inner membrane|membrane|,cholesterol metabolic process|calcitriol biosynthetic process from calciol|oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|vitamin D3 25-hydroxylase activity|cholesterol 26-hydroxylase activity|metal ion binding|cholestanetriol 26-monooxygenase activity|",10,0,0,10,0.1,0.411,0.1,0.278,0.278,0.846,0,0,-1.2,1.6
ENSMUSG00000038754,ELOVL3,"elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3",endoplasmic reticulum|membrane|integral component of membrane|,"lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation, saturated fatty acid|fatty acid elongation, saturated fatty acid|fatty acid elongation, monounsaturated fatty acid|fatty acid elongation, monounsaturated fatty acid|fatty acid elongation, polyunsaturated fatty acid|very long-chain fatty acid biosynthetic process|very long-chain fatty acid biosynthetic process|",transferase activity|,10,0,0,10,-0.3,2.34,-0.2,0.277,-0.277,0.846,0,0,-1.8,0.8
ENSMUSG00000037946,FGD3,"FYVE, RhoGEF and PH domain containing 3",cytoplasm|cytoskeleton|,regulation of Rho protein signal transduction|filopodium assembly|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|metal ion binding|,10,-0.6,1.66,10,0,0,-0.1,0.276,-0.276,0.846,0,0,-2,0.7
ENSMUSG00000050144,SLC25A44,"solute carrier family 25, member 44",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,-0.1,0.775,10,0,0,-0.1,0.274,-0.274,0.847,0,0,-1.1,1.8
ENSMUSG00000060671,ATP8B2,"ATPase, class I, type 8B, member 2",Golgi apparatus|plasma membrane|membrane|integral component of membrane|,transport|cation transport|lipid transport|phospholipid transport|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|protein binding|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,0.1,0.223,10,0.1,0.0729,0.1,0.27,0.27,0.848,0,0,-1.2,1.7
ENSMUSG00000039043,2610034B18RIK,RIKEN cDNA 2610034B18 gene,lamellipodium|cell projection|,biological_process|,molecular_function|,10,-0.2,0.139,10,0.2,0.751,0.1,0.269,0.269,0.848,0,0,-1.3,1.5
ENSMUSG00000051043,GPRC5C,"G protein-coupled receptor, family C, group 5, member C",mitochondrion|plasma membrane|membrane|integral component of membrane|receptor complex|extracellular vesicular exosome|,signal transduction|G-protein coupled receptor signaling pathway|visual perception|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|sevenless binding|,10,0.1,0.544,10,-0.2,0.252,0.1,0.264,0.264,0.849,0,0,-1.4,1.5
ENSMUSG00000048856,SLC25A47,"solute carrier family 25, member 47",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,-0.2,0.537,10,0,0,-0.1,0.255,-0.255,0.851,0,0,-1.4,1.3
ENSMUSG00000053101,GPR141,G protein-coupled receptor 141,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.1,0.315,10,0,0,0.1,0.246,0.246,0.853,0,0,-1.5,1.5
ENSMUSG00000025176,HOGA1,4-hydroxy-2-oxoglutarate aldolase 1,mitochondrion|extracellular vesicular exosome|,metabolic process|glyoxylate catabolic process|4-hydroxyproline catabolic process|oxalate metabolic process|pyruvate biosynthetic process|glyoxylate metabolic process|,catalytic activity|4-hydroxy-2-oxoglutarate aldolase activity|lyase activity|protein homodimerization activity|,10,1,2.75,10,0.1,0.00906,0.2,0.246,0.246,0.853,0,0,-0.8,2
ENSMUSG00000031367,AP1S2,"adaptor-related protein complex 1, sigma 2 subunit",Golgi apparatus|coated pit|membrane|membrane coat|cytoplasmic vesicle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,molecular_function|protein transporter activity|,10,0,0,10,-0.3,1.07,-0.1,0.246,-0.246,0.853,0,0,-1.7,1
ENSMUSG00000036872,ABCC12,"ATP-binding cassette, sub-family C (CFTR/MRP), member 12",mitochondrion|membrane|integral component of membrane|,transport|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,-0.3,0.861,10,0,0,-0.1,0.234,-0.234,0.856,0,0,-1.5,1.3
ENSMUSG00000021496,PCBD2,pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2,nucleus|mitochondrion|,"tetrahydrobiopterin biosynthetic process|positive regulation of transcription, DNA-templated|protein homotetramerization|protein heterooligomerization|oxidation-reduction process|",phenylalanine 4-monooxygenase activity|protein binding|4-alpha-hydroxytetrahydrobiopterin dehydratase activity|lyase activity|,10,0,0,10,0.3,2.23,0.2,0.232,0.232,0.856,0,0,-0.9,1.8
ENSMUSG00000042032,MAT2B,"methionine adenosyltransferase II, beta",nucleus|mitochondrion|methionine adenosyltransferase complex|,S-adenosylmethionine biosynthetic process|one-carbon metabolic process|extracellular polysaccharide biosynthetic process|regulation of catalytic activity|,dTDP-4-dehydrorhamnose reductase activity|enzyme binding|methionine adenosyltransferase regulator activity|,10,-0.2,1.27,10,0.1,0.333,-0.1,0.231,-0.231,0.857,0,0,-1.2,1.6
ENSMUSG00000036356,CSGALNACT1,chondroitin sulfate N-acetylgalactosaminyltransferase 1,Golgi apparatus|membrane|integral component of membrane|Golgi cisterna membrane|,"endochondral ossification|UDP-N-acetylgalactosamine metabolic process|extracellular matrix organization|chondroitin sulfate metabolic process|chondroitin sulfate biosynthetic process|UDP-glucuronate metabolic process|chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process|cartilage development|",acetylgalactosaminyltransferase activity|peptidoglycan glycosyltransferase activity|glucuronosyltransferase activity|transferase activity|metal ion binding|glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|,10,0,0,10,0.1,0.541,0.1,0.231,0.231,0.857,0,0,-1.2,1.7
ENSMUSG00000051359,NCALD,neurocalcin delta,intracellular|intracellular|cytosol|extracellular vesicular exosome|,regulation of systemic arterial blood pressure|calcium-mediated signaling|,actin binding|calcium ion binding|tubulin binding|clathrin binding|alpha-tubulin binding|metal ion binding|,10,-0.2,1.26,10,0,0,-0.1,0.214,-0.214,0.861,0,0,-1.7,1.1
ENSMUSG00000028434,EPB4.1L4B,erythrocyte protein band 4.1-like 4b,cytoplasm|cytoskeleton|extrinsic component of membrane|apical part of cell|,actomyosin structure organization|,protein binding|cytoskeletal protein binding|,10,0,0,10,0.4,0.857,0.1,0.212,0.212,0.861,0,0,-1,1.7
ENSMUSG00000039787,CERCAM,cerebral endothelial cell adhesion molecule,cellular_component|endoplasmic reticulum|,cell adhesion|lipopolysaccharide biosynthetic process|,molecular_function|,10,-0.2,1.37,10,0.2,0.712,-0.1,0.208,-0.208,0.862,0,0,-1.4,1.4
ENSMUSG00000075254,HEG1,HEG homolog 1 (zebrafish),plasma membrane|cell-cell junction|external side of plasma membrane|cell surface|membrane|integral component of membrane|cell junction|,vasculogenesis|in utero embryonic development|in utero embryonic development|endothelial cell development|endothelial cell morphogenesis|vasculature development|lymph vessel development|lymph circulation|cardiac atrium morphogenesis|cardiac atrium morphogenesis|ventricular trabecula myocardium morphogenesis|ventricular septum development|cell-cell junction assembly|multicellular organismal development|heart development|heart development|post-embryonic development|lung development|multicellular organism growth|cell-cell junction organization|venous blood vessel morphogenesis|regulation of body fluid levels|cardiac muscle tissue growth|pericardium development|pericardium development|positive regulation of fibroblast growth factor production|,calcium ion binding|protein binding|,10,-0.3,1.39,10,0.1,0.786,-0.1,0.205,-0.205,0.863,0,0,-1.6,1.2
ENSMUSG00000039219,ARID4B,AT rich interactive domain 4B (RBP1-like),cellular_component|intracellular|nucleus|,"regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|histone H4-K20 trimethylation|histone H3-K9 trimethylation|positive regulation of transcription from RNA polymerase II promoter|establishment of Sertoli cell barrier|",DNA binding|protein binding|,10,0.1,0.409,10,0,0,0.1,0.199,0.199,0.864,0,0,-0.9,1.9
ENSMUSG00000022679,MPV17L,"Mpv17 transgene, kidney disease mutant-like",cytoplasm|mitochondrion|peroxisome|peroxisome|membrane|integral component of membrane|,negative regulation of hydrogen peroxide biosynthetic process|reactive oxygen species metabolic process|reactive oxygen species metabolic process|negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|,receptor binding|,10,0.1,0.146,10,0.2,0.0937,0.1,0.199,0.199,0.864,0,0,-1.4,1.4
ENSMUSG00000021916,GLT8D1,glycosyltransferase 8 domain containing 1,membrane|membrane|integral component of membrane|,biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",9,-0.3,1.13,9,0.2,0.0754,-0.1,0.194,-0.194,0.865,0,0,-1.7,1.2
ENSMUSG00000032452,CLSTN2,calsyntenin 2,endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|postsynaptic membrane|postsynaptic membrane|,cell adhesion|homophilic cell adhesion|,calcium ion binding|,10,-0.2,0.764,10,0.2,0.474,0.1,0.192,0.192,0.865,0,0,-1.4,1.4
ENSMUSG00000034913,SPERT,spermatid associated,cytoplasmic membrane-bounded vesicle|,biological_process|,molecular_function|,10,0.1,0.26,10,0,0,0.1,0.192,0.192,0.865,0,0,-1.2,1.7
ENSMUSG00000062980,CPED1,cadherin-like and PC-esterase domain containing 1,endoplasmic reticulum|,biological_process|,molecular_function|,10,-0.1,1.1,10,0.1,0.281,-0.1,0.191,-0.191,0.865,0,0,-1.3,1.6
ENSMUSG00000031198,FUNDC2,FUN14 domain containing 2,nucleus|mitochondrion|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.35,-0.1,0.188,-0.188,0.866,0,0,-1.8,1
ENSMUSG00000019890,NTS,neurotensin,extracellular region|cytoplasmic vesicle|,regulation of blood vessel size|,neuropeptide hormone activity|,10,-0.2,0.572,10,0,0,-0.1,0.188,-0.188,0.866,0,0,-1.3,1.7
ENSMUSG00000027371,FAHD2A,fumarylacetoacetate hydrolase domain containing 2A,mitochondrion|,metabolic process|,catalytic activity|GPI-anchor transamidase activity|hydrolase activity|metal ion binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.1,0.529,10,0,0,-0.1,0.185,-0.185,0.867,0,0,-1.1,1.9
ENSMUSG00000036591,ARHGAP21,Rho GTPase activating protein 21,intracellular|cytoplasm|Golgi apparatus|cytoskeleton|membrane|cell junction|cytoplasmic vesicle|,Golgi organization|signal transduction|establishment of Golgi localization|maintenance of Golgi location|organelle transport along microtubule|,molecular_function|GTPase activator activity|,10,-0.1,0.66,10,0,0,-0.1,0.185,-0.185,0.867,0,0,-1.8,1.1
ENSMUSG00000006800,SULF2,sulfatase 2,extracellular space|endoplasmic reticulum|Golgi apparatus|plasma membrane|cell surface|,kidney development|chondrocyte development|glomerular filtration|sulfur compound metabolic process|metabolic process|positive regulation vascular endothelial growth factor production|esophagus smooth muscle contraction|positive regulation of Wnt signaling pathway|heparan sulfate proteoglycan metabolic process|heparan sulfate proteoglycan metabolic process|glomerular basement membrane development|glial cell-derived neurotrophic factor receptor signaling pathway|negative regulation of fibroblast growth factor receptor signaling pathway|embryonic skeletal system development|cartilage development|bone development|innervation|,catalytic activity|arylsulfatase activity|calcium ion binding|N-acetylglucosamine-6-sulfatase activity|N-acetylglucosamine-6-sulfatase activity|sulfuric ester hydrolase activity|hydrolase activity|alkyl sulfatase activity|endosulfan hemisulfate sulfatase activity|endosulfan sulfate hydrolase activity|metal ion binding|,10,0.1,0.0121,10,-0.1,0.345,-0.1,0.179,-0.179,0.868,0,0,-1.8,1.1
ENSMUSG00000027356,FERMT1,fermitin family homolog 1 (Drosophila),cytoplasm|cytosol|cytoskeleton|plasma membrane|focal adhesion|membrane|cell junction|filamentous actin|cell projection|,cell adhesion|keratinocyte proliferation|keratinocyte migration|establishment of epithelial cell polarity|,None,10,0.1,0.312,10,0,0,0.1,0.174,0.174,0.869,0,0,-1.3,1.6
ENSMUSG00000030101,SUMF1,sulfatase modifying factor 1,endoplasmic reticulum|,oxidation-reduction process|,protein binding|dimethyl sulfoxide reductase activity|oxidoreductase activity|tetrachloro-p-hydroquinone reductive dehalogenase activity|protein homodimerization activity|metal ion binding|trichloro-p-hydroquinone reductive dehalogenase activity|,10,-0.1,0.246,10,0.3,1.3,-0.1,0.173,-0.173,0.869,0,0,-1.2,1.6
ENSMUSG00000034295,FHOD3,formin homology 2 domain containing 3,cytoplasm|cytoskeleton|striated muscle thin filament|sarcomere|,actin filament organization|negative regulation of actin filament polymerization|sarcomere organization|sarcomere organization|actin filament network formation|cardiac myofibril assembly|,molecular_function|actin binding|,9,0.1,0.451,10,-0.1,0.154,0.1,0.17,0.17,0.87,0,0,-1.2,1.7
ENSMUSG00000034336,INA,"internexin neuronal intermediate filament protein, alpha",extracellular space|intermediate filament|neurofilament|cytoplasmic ribonucleoprotein granule|,multicellular organismal development|nervous system development|cell differentiation|intermediate filament cytoskeleton organization|neurofilament cytoskeleton organization|,structural molecule activity|protein binding|,10,-0.1,0.519,10,0,0,-0.1,0.163,-0.163,0.871,0,0,-1,1.8
ENSMUSG00000072473,1700024G13RIK,RIKEN cDNA 1700024G13 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,1.44,-0.1,0.162,-0.162,0.872,0,0,-1.7,1.2
ENSMUSG00000029153,OCIAD2,OCIA domain containing 2,mitochondrion|mitochondrial inner membrane|endosome|,biological_process|,molecular_function|,10,-0.2,0.39,10,0.2,0.996,-0.1,0.159,-0.159,0.872,0,0,-1.5,1.3
ENSMUSG00000052632,ASAP2,"ArfGAP with SH3 domain, ankyrin repeat and PH domain 2",cellular_component|cytoplasm|Golgi apparatus|plasma membrane|membrane|,biological_process|regulation of ARF GTPase activity|,molecular_function|GTPase activator activity|ARF GTPase activator activity|zinc ion binding|metal ion binding|,9,0.9,2.3,9,0,0,0.9,0.157,0.157,0.873,0,0,-0.6,2
ENSMUSG00000029767,CALU,calumenin,extracellular region|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum lumen|membrane|sarcoplasmic reticulum|intracellular membrane-bounded organelle|,negative regulation of catalytic activity|,enzyme inhibitor activity|calcium ion binding|calcium ion binding|enzyme binding|metal ion binding|,10,0.2,0.887,10,0,0,0.2,0.152,0.152,0.874,0,0,-1,1.8
ENSMUSG00000002661,ALKBH7,"alkB, alkylation repair homolog 7 (E. coli)",mitochondrion|mitochondrial matrix|mitochondrial matrix|,fatty acid metabolic process|cellular response to DNA damage stimulus|regulation of lipid storage|programmed cell death|oxidation-reduction process|regulation of mitochondrial membrane permeability involved in programmed necrotic cell death|,"sulfonate dioxygenase activity|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.1,0.742,10,0,0,0.1,0.152,0.152,0.874,0,0,-1.5,1.4
ENSMUSG00000051256,JAGN1,jagunal homolog 1 (Drosophila),cellular_component|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,endoplasmic reticulum organization|biological_process|,molecular_function|,10,0,0,10,-0.3,0.845,-0.1,0.152,-0.152,0.874,0,0,-1.7,1
ENSMUSG00000061048,CDH3,cadherin 3,cytoplasm|plasma membrane|plasma membrane|cell-cell adherens junction|membrane|integral component of membrane|,retina homeostasis|cell adhesion|homophilic cell adhesion|positive regulation of gene expression|positive regulation of keratinocyte proliferation|single organismal cell-cell adhesion|hair cycle process|keratinization|positive regulation of monophenol monooxygenase activity|negative regulation of transforming growth factor beta2 production|positive regulation of insulin-like growth factor receptor signaling pathway|positive regulation of melanin biosynthetic process|negative regulation of catagen|canonical Wnt signaling pathway|regulation of hair cycle by canonical Wnt signaling pathway|positive regulation of melanosome transport|,calcium ion binding|metal ion binding|,10,0,0,10,0.9,3.42,0.9,0.15,0.15,0.874,0,0,-0.5,2
ENSMUSG00000041354,RGL2,ral guanine nucleotide dissociation stimulator-like 2,intracellular|,signal transduction|small GTPase mediated signal transduction|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|,10,0,0,10,0.1,0.294,0.1,0.149,0.149,0.874,0,0,-1.3,1.6
ENSMUSG00000037509,ARHGEF4,Rho guanine nucleotide exchange factor (GEF) 4,cytoplasm|,lamellipodium assembly|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of GTPase activity|filopodium assembly|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein domain specific binding|Rac guanyl-nucleotide exchange factor activity|,10,0.1,0.295,10,0,0,0.1,0.148,0.148,0.875,0,0,-1.3,1.6
ENSMUSG00000009145,DQX1,DEAQ RNA-dependent ATPase,cellular_component|nucleus|,ATP catabolic process|,nucleotide binding|helicase activity|ATP binding|hydrolase activity|ATPase activity|,10,-0.1,0.855,10,0.2,0.759,-0.1,0.139,-0.139,0.877,0,0,-1.4,1.5
ENSMUSG00000035041,CREB3L3,cAMP responsive element binding protein 3-like 3,nucleus|endoplasmic reticulum|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to unfolded protein|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.3,0.784,0.1,0.137,0.137,0.877,0,0,-1.6,1.3
ENSMUSG00000030615,TMEM126A,transmembrane protein 126A,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,optic nerve development|,molecular_function|,10,0,0,10,-0.3,1.05,-0.1,0.133,-0.133,0.878,0,0,-1.8,1.1
ENSMUSG00000054855,RND1,Rho family GTPase 1,intracellular|cytoplasm|cytoskeleton|plasma membrane|adherens junction|membrane|,actin filament organization|negative regulation of cell adhesion|small GTPase mediated signal transduction|neuron remodeling|,nucleotide binding|receptor binding|GTP binding|,10,0,0,10,-0.1,0.308,-0.1,0.133,-0.133,0.878,0,0,-1.7,1.2
ENSMUSG00000032549,RAB6B,"RAB6B, member RAS oncogene family",cellular_component|Golgi apparatus|membrane|cytoplasmic vesicle|,transport|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|,nucleotide binding|protein binding|GTP binding|,10,0.2,0.16,10,0,0,0.2,0.133,0.133,0.878,0,0,-1.3,1.6
ENSMUSG00000029156,SGCB,"sarcoglycan, beta (dystrophin-associated glycoprotein)",cytoplasm|cytoskeleton|plasma membrane|integral component of plasma membrane|dystrophin-associated glycoprotein complex|dystroglycan complex|sarcoglycan complex|membrane|integral component of membrane|sarcolemma|,muscle organ development|muscle fiber development|cardiac muscle cell development|membrane organization|vascular smooth muscle cell development|,None,9,0.1,0.507,9,0,0,0.1,0.129,0.129,0.879,0,0,-1.2,1.8
ENSMUSG00000028438,KIF24,kinesin family member 24,cytoplasm|centriole|cytoskeleton|kinesin complex|microtubule|protein complex|,microtubule-based movement|microtubule depolymerization|metabolic process|cell projection organization|cilium assembly|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,-0.1,0.0203,10,0.2,1.17,0.1,0.123,0.123,0.88,0,0,-1,1.8
ENSMUSG00000009281,RARRES2,retinoic acid receptor responder (tazarotene induced) 2,extracellular region|extracellular matrix|extracellular vesicular exosome|,retinoid metabolic process|positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|chemotaxis|defense response|inflammatory response|positive regulation of macrophage chemotaxis|cell differentiation|positive regulation of fat cell differentiation|embryonic digestive tract development|brown fat cell differentiation|positive regulation of chemotaxis|regulation of lipid catabolic process|positive regulation of glucose import in response to insulin stimulus|positive regulation of glucose import in response to insulin stimulus|,receptor binding|protein binding|,10,-0.1,0.284,10,0,0,-0.1,0.113,-0.113,0.882,0,0,-1.6,1.3
ENSMUSG00000029507,PUS1,pseudouridine synthase 1,nuclear chromatin|nucleus|transcription factor complex|nucleolus|mitochondrion|,pseudouridine synthesis|tRNA processing|RNA modification|tRNA pseudouridine synthesis|positive regulation of transcription from RNA polymerase II promoter|,RNA binding|protein binding|pseudouridine synthase activity|pseudouridine synthase activity|isomerase activity|ligand-dependent nuclear receptor transcription coactivator activity|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|poly(A) RNA binding|baruol synthase activity|,10,0.1,0.199,10,0,0,0.1,0.104,0.104,0.884,0,0,-1.2,1.7
ENSMUSG00000027999,PLA2G12A,"phospholipase A2, group XIIA",extracellular region|intracellular|cytoplasm|endoplasmic reticulum|Golgi apparatus|,lipid metabolic process|phospholipid metabolic process|lipid catabolic process|,phospholipase A2 activity|calcium ion binding|hydrolase activity|metal ion binding|,10,0.1,0.325,10,0,0,0.1,0.0971,0.0971,0.885,0,0,-1.3,1.7
ENSMUSG00000019027,DNAH1,"dynein, axonemal, heavy chain 1",axonemal dynein complex|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|,10,-0.5,0.48,10,0.1,0.0379,-0.1,0.0956,-0.0956,0.886,0,0,-1.9,1.1
ENSMUSG00000055775,MYH8,"myosin, heavy polypeptide 8, skeletal muscle, perinatal",cytoplasm|myosin complex|myosin filament|,skeletal muscle contraction|ATP catabolic process|muscle filament sliding|,microfilament motor activity|nucleotide binding|motor activity|actin binding|protein binding|ATP binding|ATPase activity|,10,-0.1,0.0699,10,0.2,0.6,0.1,0.0943,0.0943,0.886,0,0,-1,1.8
ENSMUSG00000030306,TMTC1,transmembrane and tetratricopeptide repeat containing 1,mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.372,10,-0.1,0.215,0.1,0.0888,0.0888,0.887,0,0,-1.2,1.7
ENSMUSG00000021884,HACL1,2-hydroxyacyl-CoA lyase 1,peroxisome|peroxisome|,fatty acid alpha-oxidation|lipid metabolic process|protein oligomerization|,magnesium ion binding|catalytic activity|receptor binding|lyase activity|carbon-carbon lyase activity|thiamine pyrophosphate binding|identical protein binding|metal ion binding|cofactor binding|,10,0.2,1.13,10,0,0,0.1,0.0866,0.0866,0.887,0,0,-1.3,1.5
ENSMUSG00000027575,ARFGAP1,ADP-ribosylation factor GTPase activating protein 1,Golgi membrane|cytoplasm|Golgi apparatus|synapse|,transport|protein transport|vesicle-mediated transport|regulation of ARF GTPase activity|positive regulation of GTPase activity|,GTPase activator activity|protein binding|ARF GTPase activator activity|zinc ion binding|metal ion binding|,10,0,0,10,0.5,1.64,0.1,0.0863,0.0863,0.887,0,0,-1.4,1.6
ENSMUSG00000040322,SLC25A24,"solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24",cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|mitochondrial transport|regulation of cell death|purine nucleoside transmembrane transport|ATP transport|ion transmembrane transport|cellular response to oxidative stress|transmembrane transport|cellular response to calcium ion|nucleotide transmembrane transport|,ATP transmembrane transporter activity|calcium ion binding|metal ion binding|,10,0.1,0.228,10,-0.1,0.325,0.1,0.083,0.083,0.888,0,0,-1.4,1.5
ENSMUSG00000040618,PCK2,phosphoenolpyruvate carboxykinase 2 (mitochondrial),mitochondrion|mitochondrion|extracellular vesicular exosome|,pyruvate metabolic process|gluconeogenesis|oxaloacetate metabolic process|NADH oxidation|positive regulation of insulin secretion|,nucleotide binding|phosphoenolpyruvate carboxykinase activity|phosphoenolpyruvate carboxykinase (GTP) activity|GTP binding|lyase activity|carboxy-lyase activity|purine nucleotide binding|metal ion binding|,10,-0.1,0.0562,10,0.2,0.375,-0.1,0.0772,-0.0772,0.889,0,0,-1.5,1.4
ENSMUSG00000027456,SDCBP2,syndecan binding protein (syntenin) 2,cytoplasm|extracellular vesicular exosome|,biological_process|,protein C-terminus binding|protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,-0.2,0.417,-0.1,0.0731,-0.0731,0.89,0,0,-1,2
ENSMUSG00000089789,RDH1,retinol dehydrogenase 1 (all trans),None,retinoid metabolic process|steroid metabolic process|oxidation-reduction process|,retinol dehydrogenase activity|steroid dehydrogenase activity|,7,-0.1,0.262,7,0,0,-0.1,0.0714,-0.0714,0.891,0,0,-1.7,1.5
ENSMUSG00000075033,NXPE3,"neurexophilin and PC-esterase domain family, member 3",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0957,-0.1,0.0616,-0.0616,0.893,0,0,-1,2
ENSMUSG00000038020,RAPGEFL1,Rap guanine nucleotide exchange factor (GEF)-like 1,None,small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|,10,0,0,10,0.3,0.724,0.3,0.0474,0.0474,0.896,0,0,-0.8,1.9
ENSMUSG00000046000,NAA11,"N(alpha)-acetyltransferase 11, NatA catalytic subunit",nucleus|cytoplasm|NatA complex|,N-terminal protein amino acid acetylation|,"peptide alpha-N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.1,0.491,10,0,0,-0.1,0.0401,-0.0401,0.897,0,0,-1.3,1.7
ENSMUSG00000051276,ACTRT2,actin-related protein T2,cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,-0.1,0.389,10,0.1,0.157,-0.1,0.0379,-0.0379,0.898,0,0,-1.6,1.3
ENSMUSG00000020363,GFPT2,glutamine fructose-6-phosphate transaminase 2,None,carbohydrate metabolic process|glutamine metabolic process|metabolic process|carbohydrate biosynthetic process|,glutamine-fructose-6-phosphate transaminase (isomerizing) activity|transaminase activity|transferase activity|carbohydrate binding|,10,-0.5,0.102,10,-0.1,0.336,-0.1,0.0338,-0.0338,0.898,0,0,-1.9,1
ENSMUSG00000074657,KIF5A,kinesin family member 5A,cytoplasm|kinesin complex|kinesin complex|membrane|axon|ciliary rootlet|neuron projection|neuronal cell body|,None,microtubule motor activity|protein binding|microtubule binding|protein complex binding|,10,-0.2,0.98,10,0.2,1.19,0.1,0.0308,0.0308,0.899,0,0,-1,1.8
ENSMUSG00000045658,PID1,phosphotyrosine interaction domain containing 1,nucleus|cytoplasm|cytoplasm|,negative regulation of protein phosphorylation|positive regulation of gene expression|cellular response to leptin stimulus|positive regulation of transcription from RNA polymerase II promoter|negative regulation of glucose import|negative regulation of insulin receptor signaling pathway|regulation of mitochondrial membrane potential|positive regulation of fat cell proliferation|mitochondrion morphogenesis|cellular response to cytokine stimulus|cellular response to interleukin-6|cellular response to tumor necrosis factor|cellular response to fatty acid|negative regulation of establishment of protein localization to plasma membrane|negative regulation of mitochondrial DNA replication|regulation of G1/S transition of mitotic cell cycle|regulation of reactive oxygen species metabolic process|positive regulation of reactive oxygen species metabolic process|negative regulation of ATP biosynthetic process|positive regulation of ATP biosynthetic process|negative regulation of glucose import in response to insulin stimulus|,protein binding|,10,-0.1,0.22,10,0,0,-0.1,0.0291,-0.0291,0.899,0,0,-1.7,1.2
ENSMUSG00000030672,MYLPF,"myosin light chain, phosphorylatable, fast skeletal muscle",lysosomal membrane|myosin complex|,skeletal muscle tissue development|,calcium ion binding|structural constituent of muscle|metal ion binding|,10,-0.6,1.67,10,0,0,-0.1,0.0228,-0.0228,0.901,0,0,-2,0.9
ENSMUSG00000024124,PRSS30,"protease, serine 30",cellular_component|plasma membrane|membrane|anchored component of membrane|,proteolysis|proteolysis|transport|ion transport|sodium ion transport|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|sodium channel regulator activity|,10,0.3,0.778,10,-0.3,1.35,-0.1,0.00494,-0.00494,0.904,0,0,-1.4,1.4
ENSMUSG00000034282,EVPL,envoplakin,cornified envelope|cytoplasm|cytoskeleton|cell junction|extracellular vesicular exosome|,peptide cross-linking|keratinocyte differentiation|keratinization|,"structural molecule activity|protein binding, bridging|",10,0,0,10,1,0.846,-0.1,0.00367,-0.00367,0.905,0,0,-1,2
ENSMUSG00000028229,RMDN1,regulator of microtubule dynamics 1,cytoplasm|mitochondrion|cytoskeleton|microtubule|,biological_process|,molecular_function|,10,0,0,10,0.4,1.54,0,0,0,0.905,0,0,-0.8,1.9
ENSMUSG00000064165,KRT39,keratin 39,intermediate filament|,biological_process|,structural molecule activity|,9,0,0,9,0,0,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000015247,NIPSNAP3B,nipsnap homolog 3B (C. elegans),nucleus|cytoplasm|mitochondrion|,biological_process|,molecular_function|,10,0,0,10,0.1,0.00579,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000041696,RASL12,"RAS-like, family 12",cellular_component|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.2,1.8
ENSMUSG00000070730,RMDN3,regulator of microtubule dynamics 3,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|cytoskeleton|microtubule|membrane|integral component of membrane|,cellular calcium ion homeostasis|apoptotic process|cell differentiation|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.5
ENSMUSG00000021798,LDB3,LIM domain binding 3,cytoplasm|cytoskeleton|Z disc|Z disc|cell projection|,sarcomere organization|,protein kinase C binding|protein binding|cytoskeletal protein binding|zinc ion binding|metal ion binding|muscle alpha-actinin binding|muscle alpha-actinin binding|,10,0,0,10,0.3,0.839,0,0,0,0.905,0,0,-0.9,1.8
ENSMUSG00000028011,TDO2,"tryptophan 2,3-dioxygenase",None,tryptophan metabolic process|tryptophan catabolic process|tryptophan catabolic process to kynurenine|tryptophan catabolic process to acetyl-CoA|tryptophan catabolic process to acetyl-CoA|oxidation-reduction process|,"tryptophan 2,3-dioxygenase activity|tryptophan 2,3-dioxygenase activity|oxidoreductase activity|amino acid binding|oxygen binding|heme binding|heme binding|metal ion binding|dioxygenase activity|",10,0,0,10,0.1,0.0406,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000027864,PTGFRN,prostaglandin F2 receptor negative regulator,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,lipid particle organization|,None,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000019539,RCN3,"reticulocalbin 3, EF-hand calcium binding domain",endoplasmic reticulum|,biological_process|,calcium ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000003161,SRI,sorcin,intracellular|cell|cytoplasm|mitochondrion|endoplasmic reticulum membrane|smooth endoplasmic reticulum|cytosol|plasma membrane|plasma membrane|membrane|sarcoplasmic reticulum|Z disc|Z disc|T-tubule|axon|vesicle|chromaffin granule membrane|axon terminus|dendritic spine neck|extracellular vesicular exosome|,proteolysis|calcium ion transport|negative regulation of heart rate|positive regulation of insulin secretion involved in cellular response to glucose stimulus|cytoplasmic sequestering of transcription factor|positive regulation of release of sequestered calcium ion into cytosol|regulation of calcium ion transport|negative regulation of ryanodine-sensitive calcium-release channel activity|regulation of cardiac muscle cell contraction|regulation of relaxation of muscle|regulation of high voltage-gated calcium channel activity|regulation of cell communication by electrical coupling involved in cardiac conduction|negative regulation of transcription regulatory region DNA binding|,protease binding|calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|protein binding|metal ion binding|protein heterodimerization activity|repressing transcription factor binding|,10,0,0,10,0.2,0.535,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000058056,PALLD,"palladin, cytoskeletal associated protein",stress fiber|ruffle|podosome|nucleus|nucleus|cytoplasm|cytoskeleton|actin filament|actin filament|cell junction|filopodium|axon|cell projection|neuronal cell body|axonal growth cone|,neuron projection development|ruffle organization|positive regulation of podosome assembly|,actin binding|,10,0.2,0.0156,10,0,0,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000024044,EPB4.1L3,erythrocyte protein band 4.1-like 3,cell|cytoplasm|cytoskeleton|plasma membrane|cell-cell junction|membrane|extrinsic component of membrane|cell junction|axolemma|paranode region of axon|juxtaparanode region of axon|,protein localization to paranode region of axon|apoptotic process|cytoskeletal anchoring at plasma membrane|regulation of cell shape|cortical cytoskeleton organization|cortical actin cytoskeleton organization|paranodal junction assembly|myelin maintenance|neuron projection morphogenesis|protein localization to juxtaparanode region of axon|protein localization to plasma membrane|,actin binding|structural molecule activity|structural constituent of cytoskeleton|cytoskeletal protein binding|,10,0,0,10,0.1,0.124,0,0,0,0.905,0,0,-1.9,1.2
ENSMUSG00000017286,GLOD4,glyoxalase domain containing 4,mitochondrion|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,-1.1,1.97,0,0,0,0.905,0,0,-2,0.9
ENSMUSG00000025504,EPS8L2,EPS8-like 2,ruffle|cytoplasm|plasma membrane|ruffle membrane|protein complex|extracellular vesicular exosome|,Rho protein signal transduction|Rac protein signal transduction|positive regulation of Rho GTPase activity|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|positive regulation of ruffle assembly|,actin binding|Rho guanyl-nucleotide exchange factor activity|Rac guanyl-nucleotide exchange factor activity|actin filament binding|,10,0.4,0.145,10,-0.1,0.0672,0,0,0,0.905,0,0,-1,1.8
ENSMUSG00000003546,KLC4,kinesin light chain 4,cellular_component|cytoplasm|cytoskeleton|kinesin complex|microtubule|,biological_process|,molecular_function|microtubule motor activity|,10,0,0,10,0.1,0.0754,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000022212,CPNE6,copine VI,membrane|axon|dendrite|,biological_process|,phosphatidylserine binding|,10,0.1,0.294,10,-0.1,0.124,0,0,0,0.905,0,0,-1,1.9
ENSMUSG00000024593,MEGF10,multiple EGF-like-domains 10,phagocytic cup|plasma membrane|membrane|integral component of membrane|cell projection|,phagocytosis|cell adhesion|muscle organ development|skeletal muscle satellite cell activation|skeletal muscle satellite cell differentiation|skeletal muscle satellite cell differentiation|skeletal muscle satellite cell proliferation|homotypic cell-cell adhesion|recognition of apoptotic cell|recognition of apoptotic cell|regulation of skeletal muscle tissue development|regulation of muscle cell differentiation|muscle cell development|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.2,1.8
ENSMUSG00000033327,TNXB,tenascin XB,extracellular region|proteinaceous extracellular matrix|fibrillar collagen trimer|extracellular space|extracellular space|intracellular|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|triglyceride metabolic process|cell-matrix adhesion|single organismal cell-cell adhesion|extracellular matrix organization|collagen fibril organization|collagen metabolic process|extracellular fibril organization|regulation of JUN kinase activity|elastic fiber assembly|,collagen binding|heparin binding|,10,0.1,0.0947,10,0.3,0.331,0,0,0,0.905,0,0,-1,1.8
ENSMUSG00000007950,ABHD8,abhydrolase domain containing 8,cellular_component|,biological_process|,molecular_function|catalytic activity|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000035805,MLC1,megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human),cytoplasm|lysosome|endosome|early endosome|endoplasmic reticulum|endoplasmic reticulum|plasma membrane|plasma membrane|caveola|cell-cell junction|cell-cell junction|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|cytoplasmic vesicle|membrane raft|perinuclear region of cytoplasm|recycling endosome|,transport|ion transport|protein transport|vesicle-mediated transport|positive regulation of intracellular transport|regulation of response to osmotic stress|protein oligomerization|cellular response to cholesterol|caveolin-mediated endocytosis|,protein binding|protein transporter activity|protein complex binding|,10,0,0,10,0.1,0.118,0,0,0,0.905,0,0,-1.5,1.4
ENSMUSG00000030545,PEX11A,peroxisomal biogenesis factor 11 alpha,peroxisome|peroxisomal membrane|integral component of peroxisomal membrane|membrane|integral component of membrane|protein complex|,peroxisome organization|signal transduction|peroxisome membrane biogenesis|peroxisome fission|regulation of peroxisome size|brown fat cell differentiation|,protein homodimerization activity|,10,0,0,10,0.1,0.322,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000047193,DYNC2H1,dynein cytoplasmic 2 heavy chain 1,intracellular|cell|cytoplasm|Golgi apparatus|cytoskeleton|microtubule|plasma membrane|cilium|axoneme|membrane|dynein complex|motile primary cilium|cell projection|apical part of cell|extracellular vesicular exosome|,microtubule-based movement|Golgi organization|multicellular organismal development|determination of left/right symmetry|asymmetric protein localization|dorsal/ventral pattern formation|dorsal/ventral pattern formation|protein processing|spinal cord motor neuron differentiation|cell projection organization|neuron differentiation|embryonic limb morphogenesis|forebrain development|intraciliary retrograde transport|cilium assembly|positive regulation of smoothened signaling pathway|cilium morphogenesis|,nucleotide binding|motor activity|microtubule motor activity|ATP binding|ATPase activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.1,2
ENSMUSG00000022255,MTDH,metadherin,nucleus|nucleolus|nucleolus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|tight junction|membrane|integral component of membrane|apical plasma membrane|nuclear body|cell junction|intercellular canaliculus|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|positive regulation of autophagy|lipopolysaccharide-mediated signaling pathway|negative regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of angiogenesis|positive regulation of NF-kappaB transcription factor activity|positive regulation of protein kinase B signaling|,RNA polymerase II transcription factor binding|transcription coactivator activity|double-stranded RNA binding|protein binding|poly(A) RNA binding|NF-kappaB binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000018417,MYO1B,myosin IB,cytoplasm|early endosome|actin filament|plasma membrane|brush border|endosome membrane|myosin complex|filopodium|trans-Golgi network membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|cell periphery|,ATP catabolic process|post-Golgi vesicle-mediated transport|actin filament organization|metabolic process|actin filament-based movement|actin filament bundle assembly|,"microfilament motor activity|nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|actin-dependent ATPase activity|actin filament binding|",10,0.1,0.555,10,0,0,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000029055,PLCH2,"phospholipase C, eta 2",cytoplasm|plasma membrane|membrane|,lipid metabolic process|signal transduction|lipid catabolic process|intracellular signal transduction|phosphatidylinositol metabolic process|,phosphatidylinositol phospholipase C activity|phospholipase C activity|signal transducer activity|calcium ion binding|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|,10,0,0,10,0.3,1.2,0,0,0,0.905,0,0,-1.1,1.8
ENSMUSG00000033187,BC016579,"cDNA sequence, BC016579",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.3,0.601,0,0,0,0.905,0,0,-1.2,1.7
ENSMUSG00000022340,SYBU,syntabulin (syntaxin-interacting),Golgi apparatus|membrane|integral component of membrane|dense body|,regulation of insulin secretion involved in cellular response to glucose stimulus|,microtubule binding|syntaxin-1 binding|kinesin binding|,10,0,0,10,0.3,0.597,0,0,0,0.905,0,0,-1.2,1.7
ENSMUSG00000062007,HSH2D,hematopoietic SH2 domain containing,cytoplasm|mitochondrion|cytosol|,negative regulation of B cell apoptotic process|positive regulation of signal transduction|T cell activation|negative regulation of mitochondrial depolarization|,SH3/SH2 adaptor activity|,10,-0.1,0.628,10,0,0,0,0,0,0.905,0,0,-1.8,1.2
ENSMUSG00000024269,TPGS2,tubulin polyglutamylase complex subunit 2,cellular_component|cytoplasm|cytoskeleton|microtubule|,biological_process|,molecular_function|,10,0,0,10,0.1,0.256,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000028743,AKR7A5,"aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase)",cytoplasm|mitochondrion|Golgi apparatus|extracellular vesicular exosome|,daunorubicin metabolic process|doxorubicin metabolic process|oxidation-reduction process|,"alditol:NADP+ 1-oxidoreductase activity|oxidoreductase activity|phenanthrene-9,10-epoxide hydrolase activity|",10,0.1,0.371,10,0,0,0,0,0,0.905,0,0,-1.4,1.5
ENSMUSG00000031827,COTL1,coactosin-like 1 (Dictyostelium),intracellular|nucleus|cytoplasm|cytoskeleton|membrane|extracellular vesicular exosome|,defense response to fungus|,actin binding|actin binding|protein binding|enzyme binding|enzyme binding|,10,0,0,10,-0.1,0.026,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000046027,STARD5,StAR-related lipid transfer (START) domain containing 5,None,transport|lipid transport|,lipid binding|cholesterol binding|,10,0,0,10,-0.1,0.342,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000022769,SDF2L1,stromal cell-derived factor 2-like 1,endoplasmic reticulum|endoplasmic reticulum|membrane|,response to endoplasmic reticulum stress|regulation of apoptotic process|cellular response to misfolded protein|ER-associated misfolded protein catabolic process|,chaperone binding|ATPase binding|misfolded protein binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1,2
ENSMUSG00000028116,MYOZ2,myozenin 2,cytoplasm|actin cytoskeleton|actin cytoskeleton|Z disc|,None,actin binding|telethonin binding|,10,0,0,10,-0.1,0.153,0,0,0,0.905,0,0,-1.9,1.1
ENSMUSG00000017837,NKIRAS2,NFKB inhibitor interacting Ras-like protein 2,cytoplasm|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|,nucleotide binding|GTP binding|,10,-0.1,0.473,10,0,0,0,0,0,0.905,0,0,-1.3,1.7
ENSMUSG00000015970,CHDH,choline dehydrogenase,mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|membrane|,alcohol metabolic process|glycine betaine biosynthetic process from choline|oxidation-reduction process|,"choline dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|flavin adenine dinucleotide binding|",10,0,0,10,0,0,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000063275,PTPLA,"protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|multicellular organismal development|regulation of G2/M transition of mitotic cell cycle|myotube differentiation|regulation of G1/S transition of mitotic cell cycle|,molecular_function|lyase activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.4,1.8
ENSMUSG00000037905,BRI3BP,Bri3 binding protein,mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.5
ENSMUSG00000027380,ACOXL,acyl-Coenzyme A oxidase-like,peroxisome|,fatty acid metabolic process|fatty acid beta-oxidation|metabolic process|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|acyl-CoA oxidase activity|palmitoyl-CoA oxidase activity|pristanoyl-CoA oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|very-long-chain fatty acyl-CoA oxidase activity|flavin adenine dinucleotide binding|",10,0.3,0.276,10,-0.1,0.0824,0,0,0,0.905,0,0,-1.1,1.8
ENSMUSG00000026339,CCDC93,coiled-coil domain containing 93,cellular_component|,biological_process|,molecular_function|,10,0.4,1.19,10,-0.2,0.603,0,0,0,0.905,0,0,-1.1,1.7
ENSMUSG00000046697,ENPP7,ectonucleotide pyrophosphatase/phosphodiesterase 7,Golgi apparatus|microvillus|,sphingomyelin metabolic process|sphingomyelin catabolic process|negative regulation of DNA replication|negative regulation of cell proliferation|,sphingomyelin phosphodiesterase activity|,10,-0.1,0.272,10,0.1,0.0089,0,0,0,0.905,0,0,-1.7,1.2
ENSMUSG00000029406,PITPNM2,"phosphatidylinositol transfer protein, membrane-associated 2",intracellular|cytoplasm|cytoskeleton|membrane|intracellular membrane-bounded organelle|,transport|biological_process|,phospholipid binding|lipid binding|metal ion binding|,10,-0.1,0.463,10,0.3,0.197,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000029381,SHROOM3,shroom family member 3,cytoplasm|cytoskeleton|microtubule|adherens junction|apical plasma membrane|cell junction|apical junction complex|apical part of cell|,cell morphogenesis|neural tube closure|columnar/cuboidal epithelial cell development|multicellular organismal development|pattern specification process|regulation of cell shape|actin cytoskeleton organization|,actin binding|,10,0.1,0.446,10,-0.3,0.869,0,0,0,0.905,0,0,-2,0.8
ENSMUSG00000042353,FREM3,Fras1 related extracellular matrix protein 3,extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|integral component of membrane|,cell communication|cell adhesion|,metal ion binding|,10,-0.1,0.268,10,0.1,0.464,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000024990,RBP4,"retinol binding protein 4, plasma",extracellular region|extracellular space|extracellular space|protein complex|extracellular vesicular exosome|,eye development|eye development|gluconeogenesis|gluconeogenesis|transport|spermatogenesis|heart development|male gonad development|embryo development|maintenance of gastrointestinal epithelium|lung development|positive regulation of insulin secretion|response to retinoic acid|response to insulin|retinol transport|retinol transport|retinol transport|retinol metabolic process|retinol metabolic process|retinal metabolic process|glucose homeostasis|embryonic organ morphogenesis|embryonic skeletal system development|cardiac muscle tissue development|female genitalia morphogenesis|detection of light stimulus involved in visual perception|positive regulation of immunoglobulin secretion|vitamin transport|retina development in camera-type eye|negative regulation of cardiac muscle cell proliferation|embryonic retina morphogenesis in camera-type eye|uterus development|vagina development|urinary bladder development|heart trabecula formation|,transporter activity|retinoid binding|protein binding|retinal binding|retinol binding|retinol binding|retinol transporter activity|retinol transporter activity|small molecule binding|protein heterodimerization activity|,10,0,0,10,0.1,0.119,0,0,0,0.905,0,0,-1.1,2
ENSMUSG00000034220,GPC1,glypican 1,extracellular region|proteinaceous extracellular matrix|endosome|plasma membrane|membrane|anchored component of membrane|neuronal cell body|membrane raft|membrane raft|extracellular vesicular exosome|,Schwann cell differentiation|heparan sulfate proteoglycan catabolic process|myelin assembly|negative regulation of fibroblast growth factor receptor signaling pathway|,copper ion binding|fibroblast growth factor binding|laminin binding|heparan sulfate proteoglycan binding|collagen V binding|,10,0,0,10,0.1,0.114,0,0,0,0.905,0,0,-1.3,1.7
ENSMUSG00000027400,PDYN,prodynorphin,extracellular region|plasma membrane|,neuropeptide signaling pathway|synaptic transmission|,opioid peptide activity|neuropeptide hormone activity|,10,0.1,0.161,10,0,0,0,0,0,0.905,0,0,-1.3,1.7
ENSMUSG00000032517,MOBP,myelin-associated oligodendrocytic basic protein,cytoplasm|mitochondrion|,intracellular protein transport|nervous system development|,Rab GTPase binding|structural constituent of myelin sheath|structural constituent of myelin sheath|,10,-0.1,0.236,10,0.8,2.62,0,0,0,0.905,0,0,-0.5,2
ENSMUSG00000033987,DNAH17,"dynein, axonemal, heavy chain 17",cellular_component|cytoplasm|cytoskeleton|microtubule|cilium|dynein complex|cell projection|,microtubule-based movement|biological_process|,nucleotide binding|motor activity|microtubule motor activity|protein binding|ATP binding|ATPase activity|,10,0,0,10,-0.1,0.265,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000062373,TMEM65,transmembrane protein 65,mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.5,0.101,0,0,0,0.905,0,0,-1,2
ENSMUSG00000032754,SLC8B1,"solute carrier family 8 (sodium/lithium/calcium exchanger), member B1",mitochondrion|mitochondrial inner membrane|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|integral component of mitochondrial membrane|sarcolemma|,transport|ion transport|sodium ion transport|calcium ion transport|mitochondrial calcium ion transport|mitochondrial calcium ion transport|sodium ion transmembrane transport|sodium ion transmembrane transport|glucose homeostasis|regulation of insulin secretion|response to stimulus|transmembrane transport|calcium ion transmembrane transport|calcium ion transmembrane transport|,calcium:sodium antiporter activity|calcium:sodium antiporter activity|antiporter activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.8,1.3
ENSMUSG00000037890,WDR19,WD repeat domain 19,intracellular|cell|cytoplasm|cytoskeleton|cilium|cilium|intraciliary transport particle A|intraciliary transport particle A|nonmotile primary cilium|motile cilium|photoreceptor connecting cilium|cell projection|,cell morphogenesis|in utero embryonic development|smoothened signaling pathway|cell projection organization|embryonic limb morphogenesis|embryonic camera-type eye development|intraciliary retrograde transport|cilium assembly|cilium assembly|ear morphogenesis|embryonic cranial skeleton morphogenesis|neurological system process|digestive system development|cilium morphogenesis|cilium morphogenesis|cilium morphogenesis|ciliary receptor clustering involved in smoothened signaling pathway|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|myotome development|protein localization to cilium|,molecular_function|,10,-0.1,0.421,10,0,0,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000029656,C8B,"complement component 8, beta polypeptide",extracellular region|membrane attack complex|extracellular space|,"immune system process|immune response|complement activation, alternative pathway|complement activation, classical pathway|cytolysis|innate immune response|",protein complex binding|,10,0,0,10,-0.1,0.0205,0,0,0,0.905,0,0,-1.8,1.3
ENSMUSG00000021262,EVL,Ena-vasodilator stimulated phosphoprotein,cytoplasm|cytoskeleton|focal adhesion|membrane|lamellipodium|cell projection|,axon guidance|actin polymerization or depolymerization|negative regulation of epithelial cell migration|actin filament-based movement|platelet activation|positive regulation of actin filament polymerization|actin nucleation|barbed-end actin filament capping|protein homotetramerization|positive regulation of stress fiber assembly|negative regulation of ruffle assembly|,actin binding|protein binding|profilin binding|SH3 domain binding|,10,0.1,0.27,10,-0.1,0.211,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000025815,DHTKD1,dehydrogenase E1 and transketolase domain containing 1,mitochondrion|,hematopoietic progenitor cell differentiation|generation of precursor metabolites and energy|glycolytic process|tricarboxylic acid cycle|metabolic process|oxidation-reduction process|,"molecular_function|oxoglutarate dehydrogenase (succinyl-transferring) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor|thiamine pyrophosphate binding|",10,-0.1,0.223,10,1.2,0.658,0,0,0,0.905,0,0,-0.9,2
ENSMUSG00000023952,GTPBP2,GTP binding protein 2,intracellular membrane-bounded organelle|,None,nucleotide binding|GTPase activity|GTP binding|,10,-0.1,0.388,10,0,0,0,0,0,0.905,0,0,-1,2
ENSMUSG00000020758,ITGB4,integrin beta 4,basement membrane|cytoplasm|plasma membrane|cell cortex|integrin complex|basal plasma membrane|cell surface|membrane|integral component of membrane|cell junction|hemidesmosome|hemidesmosome|cell leading edge|receptor complex|extracellular vesicular exosome|,autophagy|cell communication|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|multicellular organismal development|response to wounding|hemidesmosome assembly|filopodium assembly|cell motility|,G-protein coupled receptor binding|receptor activity|,10,0,0,10,0.3,1.83,0,0,0,0.905,0,0,-0.7,2
ENSMUSG00000039376,SYNPO2L,synaptopodin 2-like,nucleus|cytoplasm|cytoskeleton|Z disc|,biological_process|,actin binding|protein binding|,9,0,0,10,-0.2,0.637,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000001666,DDT,D-dopachrome tautomerase,cytoplasm|extracellular vesicular exosome|,melanin biosynthetic process|,lyase activity|D-dopachrome decarboxylase activity|,8,0,0,8,-0.1,0.0584,0,0,0,0.905,0,0,-1.7,1.5
ENSMUSG00000044199,S1PR4,sphingosine-1-phosphate receptor 4,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|sphingosine-1-phosphate receptor activity|,10,-0.2,0.263,10,0,0,0,0,0,0.905,0,0,-1.9,1
ENSMUSG00000039529,ATP8B1,"ATPase, class I, type 8B, member 1",endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|apical plasma membrane|brush border membrane|stereocilium|cell projection|,"transport|cation transport|drug transmembrane transport|lipid transport|sensory perception of sound|bile acid metabolic process|phospholipid transport|vestibulocochlear nerve formation|regulation of microvillus assembly|phospholipid translocation|negative regulation of transcription, DNA-templated|inner ear receptor cell development|",nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,-0.1,0.24,10,1.2,0.491,0,0,0,0.905,0,0,-0.8,2
ENSMUSG00000001983,TACO1,translational activator of mitochondrially encoded cytochrome c oxidase I,nucleus|mitochondrion|mitochondrion|,regulation of translation|biological_process|,molecular_function|,10,0,0,10,0.2,0.427,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000021087,RTN1,reticulon 1,endoplasmic reticulum|smooth endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,None,10,0,0,10,0.1,0.283,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000041205,MAP6D1,MAP6 domain containing 1,cytoplasm|Golgi apparatus|Golgi-associated vesicle|cis-Golgi network|cytoskeleton|microtubule|,microtubule cytoskeleton organization|negative regulation of microtubule depolymerization|N-terminal peptidyl-L-cysteine N-palmitoylation|lysosome localization|dendrite morphogenesis|,calmodulin binding|microtubule binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.2,1.8
ENSMUSG00000037211,SPRY1,sprouty homolog 1 (Drosophila),cell|cytoplasm|membrane|,establishment of mitotic spindle orientation|metanephros development|ureteric bud development|ureteric bud development|organ induction|multicellular organismal development|negative regulation of cell proliferation|regulation of signal transduction|negative regulation of Ras GTPase activity|negative regulation of fibroblast growth factor receptor signaling pathway|negative regulation of MAP kinase activity|negative regulation of Ras protein signal transduction|negative regulation of neurotrophin TRK receptor signaling pathway|bud elongation involved in lung branching|negative regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 and ERK2 cascade|,protein binding|,10,0,0,10,-0.2,0.612,0,0,0,0.905,0,0,-2,0.9
ENSMUSG00000009563,TOR2A,"torsin family 2, member A",endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|,chaperone mediated protein folding requiring cofactor|protein homooligomerization|protein homooligomerization|,nucleotide binding|protein binding|ATP binding|,10,0,0,10,-0.6,1.8,0,0,0,0.905,0,0,-2,0.7
ENSMUSG00000022561,GPAA1,GPI anchor attachment protein 1,endoplasmic reticulum|integral component of plasma membrane|membrane|membrane|integral component of membrane|GPI-anchor transamidase complex|,GPI anchor biosynthetic process|,GPI-anchor transamidase activity|GPI anchor binding|,10,0.2,0.461,10,0,0,0,0,0,0.905,0,0,-1.2,1.8
ENSMUSG00000045545,KRT14,keratin 14,intracellular|nucleus|cytoplasm|intermediate filament|keratin filament|keratin filament|extracellular vesicular exosome|cell periphery|,aging|epithelial cell differentiation|epithelial cell differentiation|hair cycle|intermediate filament bundle assembly|,structural molecule activity|protein binding|keratin filament binding|,10,0.1,0.184,10,0,0,0,0,0,0.905,0,0,-1.7,1.2
ENSMUSG00000024391,APOM,apolipoprotein M,extracellular region|extracellular space|very-low-density lipoprotein particle|low-density lipoprotein particle|high-density lipoprotein particle|high-density lipoprotein particle|discoidal high-density lipoprotein particle|discoidal high-density lipoprotein particle|spherical high-density lipoprotein particle|extracellular vesicular exosome|,transport|lipid transport|cholesterol efflux|cholesterol efflux|high-density lipoprotein particle remodeling|high-density lipoprotein particle remodeling|high-density lipoprotein particle assembly|high-density lipoprotein particle clearance|negative regulation of plasma lipoprotein particle oxidation|negative regulation of plasma lipoprotein particle oxidation|lipoprotein metabolic process|reverse cholesterol transport|,lipid transporter activity|phospholipid binding|phospholipid binding|antioxidant activity|antioxidant activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000056296,SYNPR,synaptoporin,synaptic vesicle|membrane|integral component of membrane|cell junction|integral component of synaptic vesicle membrane|integral component of synaptic vesicle membrane|cytoplasmic vesicle|neuron projection|synapse|,transport|,transporter activity|,10,-0.1,0.0676,10,0,0,0,0,0,0.905,0,0,-0.8,2
ENSMUSG00000036257,PNPLA8,patatin-like phospholipase domain containing 8,intracellular|cytoplasm|peroxisome|peroxisomal membrane|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|metabolic process|cell death|lipid catabolic process|arachidonic acid metabolic process|phosphatidylcholine catabolic process|linoleic acid metabolic process|phosphatidylethanolamine catabolic process|arachidonic acid secretion|,lysophospholipase activity|hydrolase activity|calcium-independent phospholipase A2 activity|,10,-0.1,0.275,10,0,0,0,0,0,0.905,0,0,-1.7,1.2
ENSMUSG00000079605,ZBTB9,zinc finger and BTB domain containing 9,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.2,0.228,10,-0.1,0.0147,0,0,0,0.905,0,0,-1.4,1.5
ENSMUSG00000015001,OC90,otoconin 90,extracellular region|proteinaceous extracellular matrix|,phospholipid metabolic process|lipid catabolic process|,phospholipase A2 activity|structural molecule activity|structural molecule activity|calcium ion binding|,9,0,0,9,0.3,1.26,0,0,0,0.905,0,0,-1.1,1.8
ENSMUSG00000001804,DSG4,desmoglein 4,plasma membrane|membrane|integral component of membrane|cell junction|desmosome|,hair follicle development|cell adhesion|homophilic cell adhesion|single organismal cell-cell adhesion|keratinocyte differentiation|BMP signaling pathway|anagen|,calcium ion binding|metal ion binding|,10,0,0,10,0.1,0.0133,0,0,0,0.905,0,0,-1.2,1.9
ENSMUSG00000041052,SLC7A13,"solute carrier family 7, (cationic amino acid transporter, y+ system) member 13",membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|,amino acid transmembrane transporter activity|,9,0,0,10,-0.3,0.807,0,0,0,0.905,0,0,-1.8,1.1
ENSMUSG00000038555,REEP2,receptor accessory protein 2,intracellular|endoplasmic reticulum|cytoplasmic microtubule|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,protein transport into membrane raft|sensory perception of bitter taste|sensory perception of sweet taste|endoplasmic reticulum tubular network organization|,taste receptor binding|,10,0.1,0.0976,10,1.2,0.443,0,0,0,0.905,0,0,-0.8,2
ENSMUSG00000040752,MYH6,"myosin, heavy polypeptide 6, cardiac muscle, alpha",stress fiber|nucleus|cytoplasm|mitochondrion|muscle myosin complex|focal adhesion|myosin complex|myofibril|myofibril|Z disc|myosin filament|,in utero embryonic development|regulation of the force of heart contraction|regulation of the force of heart contraction|regulation of heart rate|regulation of heart rate|ATP catabolic process|muscle contraction|striated muscle contraction|striated muscle contraction|adult heart development|adult heart development|visceral muscle development|regulation of heart contraction|regulation of blood pressure|actin filament-based movement|muscle filament sliding|myofibril assembly|BMP signaling pathway|regulation of ATPase activity|sarcomere organization|cardiac muscle fiber development|atrial cardiac muscle tissue morphogenesis|ventricular cardiac muscle tissue morphogenesis|canonical Wnt signaling pathway|regulation of heart growth|,microfilament motor activity|microfilament motor activity|nucleotide binding|motor activity|actin binding|protein binding|calmodulin binding|ATP binding|ATPase activity|protein kinase binding|actin-dependent ATPase activity|calcium-dependent ATPase activity|identical protein binding|protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,0.3,0.136,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000022303,DCSTAMP,dentrocyte expressed seven transmembrane protein,endosome|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|plasma membrane|integral component of plasma membrane|cell surface|cell surface|endosome membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,immune system process|cell differentiation|negative regulation of cell growth|osteoclast differentiation|positive regulation of macrophage fusion|positive regulation of macrophage fusion|positive regulation of macrophage fusion|cellular response to macrophage colony-stimulating factor stimulus|myeloid dendritic cell differentiation|positive regulation of monocyte differentiation|positive regulation of bone resorption|membrane fusion|membrane fusion|cellular response to interleukin-4|cellular response to tumor necrosis factor|osteoclast fusion|osteoclast fusion|,None,10,0.9,1.33,10,-0.3,0.703,0,0,0,0.905,0,0,-0.8,2
ENSMUSG00000030120,MLF2,myeloid leukemia factor 2,nucleus|cytoplasm|membrane|,defense response|,protein binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000031139,MCF2,mcf.2 transforming sequence,extracellular vesicular exosome|,dendrite development|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|protein binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-0.9,2
ENSMUSG00000052087,RGS14,regulator of G-protein signaling 14,spindle pole|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|centrosome|centrosome|spindle|spindle|cytoskeleton|microtubule|plasma membrane|plasma membrane|plasma membrane|postsynaptic density|membrane|nuclear body|cell junction|dendrite|dendrite|cell projection|dendritic spine|synapse|postsynaptic membrane|,nucleocytoplasmic transport|nucleocytoplasmic transport|response to oxidative stress|cell cycle|spindle organization|spindle organization|chromosome segregation|mitotic nuclear division|signal transduction|G-protein coupled receptor signaling pathway|multicellular organismal development|learning|long-term memory|regulation of G-protein coupled receptor protein signaling pathway|visual learning|negative regulation of signal transduction|zygote asymmetric cell division|negative regulation of synaptic plasticity|intracellular signal transduction|termination of G-protein coupled receptor signaling pathway|negative regulation of MAP kinase activity|positive regulation of GTPase activity|positive regulation of GTPase activity|regulation of DNA-templated transcription in response to stress|platelet-derived growth factor receptor signaling pathway|positive regulation of neurogenesis|cell division|long-term synaptic potentiation|negative regulation of ERK1 and ERK2 cascade|,G-protein alpha-subunit binding|receptor signaling protein activity|GDP-dissociation inhibitor activity|GTPase activator activity|GTPase activator activity|GTPase activator activity|GTPase activator activity|protein binding|microtubule binding|protein kinase binding|receptor signaling complex scaffold activity|GTPase regulator activity|GTPase activating protein binding|,10,0,0,10,-0.3,1.08,0,0,0,0.905,0,0,-1.8,1.1
ENSMUSG00000031461,MYOM2,myomesin 2,mitochondrion|cytoskeleton|M band|,muscle contraction|,structural constituent of cytoskeleton|,10,0,0,10,-0.1,0.395,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000059810,RGS3,regulator of G-protein signaling 3,nucleus|cytoplasm|cytoplasm|plasma membrane|plasma membrane|membrane|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|GTPase activator activity|,10,-0.1,0.499,10,0.3,0.435,0,0,0,0.905,0,0,-1.3,1.5
ENSMUSG00000023484,PRPH,peripherin,intermediate filament|neurofilament|membrane|axon|photoreceptor outer segment membrane|neuronal cell body|C-fiber|type III intermediate filament|,intermediate filament cytoskeleton organization|intermediate filament cytoskeleton organization|,structural molecule activity|protein binding|,10,-0.1,0.0609,10,0.4,2.39,0,0,0,0.905,0,0,-1,1.7
ENSMUSG00000055827,GSDMC3,gasdermin C3,cytoplasm|mitochondrion|microtubule organizing center|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.7
ENSMUSG00000021792,FAM213A,"family with sequence similarity 213, member A",cytoplasm|mitochondrion|extracellular vesicular exosome|,regulation of osteoclast differentiation|oxidation-reduction process|,antioxidant activity|,10,0,0,10,1.1,1.65,0,0,0,0.905,0,0,-0.8,2
ENSMUSG00000030613,CCDC90B,coiled-coil domain containing 90B,mitochondrion|mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.173,10,0.1,0.108,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000071253,SLC25A16,"solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000043284,TMEM11,transmembrane protein 11,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial inner membrane|,mitochondrion organization|,molecular_function|,10,0,0,10,0.1,0.179,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000038244,MICAL2,"microtubule associated monooxygenase, calponin and LIM domain containing 2",nucleus|,cytoskeleton organization|metabolic process|positive regulation of transcription via serum response element binding|sulfur oxidation|sulfur oxidation|actin filament depolymerization|actin filament depolymerization|oxidation-reduction process|,"actin binding|actin binding|monooxygenase activity|zinc ion binding|3-(3-hydroxyphenyl)propionate hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen|4-chlorobenzaldehyde oxidase activity|3,5-xylenol methylhydroxylase activity|phenylacetate hydroxylase activity|4-nitrophenol 4-monooxygenase activity|dimethyl sulfide monooxygenase activity|alpha-pinene monooxygenase [NADH] activity|phenanthrene 9,10-monooxygenase activity|1-hydroxy-2-naphthoate hydroxylase activity|toluene 4-monooxygenase activity|xylene monooxygenase activity|dibenzothiophene monooxygenase activity|6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|chlorophenol 4-monooxygenase activity|carbon disulfide oxygenase activity|toluene 2-monooxygenase activity|1-hydroxy-2-oxolimonene 1,2-monooxygenase activity|phenanthrene 1,2-monooxygenase activity|tetrahydrofuran hydroxylase activity|styrene monooxygenase activity|toluene-4-sulfonate monooxygenase activity|toluene-sulfonate methyl-monooxygenase activity|3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|2-hydroxy-phenylacetate hydroxylase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity|phenanthrene 3,4-monooxygenase activity|toluene 3-monooxygenase activity|4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity|limonene monooxygenase activity|2-methylnaphthalene hydroxylase activity|1-methylnaphthalene hydroxylase activity|bisphenol A hydroxylase A activity|salicylate 5-hydroxylase activity|isobutylamine N-hydroxylase activity|branched-chain dodecylbenzene sulfonate monooxygenase activity|3-HSA hydroxylase activity|4-hydroxypyridine-3-hydroxylase activity|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity|6-hydroxynicotinate 3-monooxygenase activity|NADPH:sulfur oxidoreductase activity|metal ion binding|tocotrienol omega-hydroxylase activity|thalianol hydroxylase activity|",10,0,0,10,0.1,0.0877,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000036533,CDC42EP3,CDC42 effector protein (Rho GTPase binding) 3,cytoplasm|cytoskeleton|actin cytoskeleton|membrane|,biological_process|regulation of cell shape|,protein binding|,10,-0.2,0.954,10,0,0,0,0,0,0.905,0,0,-1.7,1.2
ENSMUSG00000032278,PAQR5,progestin and adipoQ receptor family member V,membrane|integral component of membrane|,multicellular organismal development|cell differentiation|oogenesis|,receptor activity|steroid binding|lipid binding|,10,-0.8,2.24,10,0,0,0,0,0,0.905,0,0,-2,0.6
ENSMUSG00000020340,CYFIP2,cytoplasmic FMR1 interacting protein 2,cytoplasm|membrane|cell junction|neuron projection|synapse|perinuclear region of cytoplasm|extracellular vesicular exosome|,apoptotic process|cell adhesion|single organismal cell-cell adhesion|positive regulation of proteolysis|activation of cysteine-type endopeptidase activity|,protein binding|,10,0,0,10,0.1,0.502,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000026961,LRRC26,leucine rich repeat containing 26,cytoplasm|cytoskeleton|plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|biological_process|,potassium channel regulator activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.4,1.7
ENSMUSG00000031442,MCF2L,mcf.2 transforming sequence-like,extracellular space|intracellular|cytoplasm|plasma membrane|membrane|lamellipodium|,Rho protein signal transduction|positive regulation of Rho GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of transcription from RNA polymerase II promoter|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|1-phosphatidylinositol binding|,10,-0.5,0.863,10,0.1,0.0277,0,0,0,0.905,0,0,-1.8,1.1
ENSMUSG00000059898,DSC3,desmocollin 3,extracellular region|cytoplasm|plasma membrane|membrane|integral component of membrane|cell junction|desmosome|,in utero embryonic development|cell adhesion|homophilic cell adhesion|protein stabilization|,calcium ion binding|gamma-catenin binding|metal ion binding|,10,0,0,10,0.1,0.0813,0,0,0,0.905,0,0,-1.4,1.5
ENSMUSG00000029432,GBAS,glioblastoma amplified sequence,mitochondrion|mitochondrion|,oxidative phosphorylation|ATP biosynthetic process|negative regulation of ATP citrate synthase activity|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.4
ENSMUSG00000041144,DNAH7B,"dynein, axonemal, heavy chain 7B",cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0.2,0.552,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000071454,DTNB,"dystrobrevin, beta",cytoplasm|synapse|,None,calcium ion binding|protein binding|zinc ion binding|metal ion binding|,10,0,0,10,1.3,0.363,0,0,0,0.905,0,0,-0.9,2
ENSMUSG00000030760,ACER3,alkaline ceramidase 3,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|integral component of endoplasmic reticulum membrane|,ceramide metabolic process|positive regulation of cell proliferation|sphingosine biosynthetic process|phytosphingosine biosynthetic process|,"histone deacetylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|phytoceramidase activity|",10,0,0,10,-0.2,0.704,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000034786,GPSM3,"G-protein signalling modulator 3 (AGS3-like, C. elegans)",cytoplasm|,regulation of G-protein coupled receptor protein signaling pathway|,GDP-dissociation inhibitor activity|GTPase regulator activity|,10,0.1,0.237,10,0,0,0,0,0,0.905,0,0,-1.3,1.7
ENSMUSG00000021895,ARHGEF3,Rho guanine nucleotide exchange factor (GEF) 3,intracellular|cytoplasm|,regulation of Rho protein signal transduction|intracellular signal transduction|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0,0,10,0.4,0.678,0,0,0,0.905,0,0,-1,1.9
ENSMUSG00000019478,RAB4A,"RAB4A, member RAS oncogene family",cytoplasm|endosome|cytosol|plasma membrane|membrane|vesicle|insulin-responsive compartment|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|recycling endosome|extracellular vesicular exosome|,GTP catabolic process|transport|small GTPase mediated signal transduction|protein transport|antigen processing and presentation|regulation of endocytosis|Rab protein signal transduction|positive regulation of ATPase activity|,nucleotide binding|ATPase activator activity|GTPase activity|protein binding|GTP binding|protein transporter activity|GDP binding|syntaxin binding|ionotropic glutamate receptor binding|ATPase binding|,10,0,0,10,-0.1,0.0342,0,0,0,0.905,0,0,-1.9,1
ENSMUSG00000028576,IFT74,intraflagellar transport 74,intracellular|cell|nucleus|centrosome|cilium|cilium|intraciliary transport particle B|cytoplasmic vesicle|cell projection|,keratinocyte development|Notch signaling pathway|epidermis development|cell projection organization|positive regulation of cell adhesion mediated by integrin|intraciliary transport involved in cilium morphogenesis|intraciliary transport|intraciliary transport|cilium assembly|cilium assembly|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of epithelial cell proliferation|cilium morphogenesis|,chromatin binding|beta-tubulin binding|beta-tubulin binding|,10,0.3,0.312,10,0,0,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000030588,YIF1B,Yip1 interacting factor homolog B (S. cerevisiae),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,0.0984,10,-0.1,0.0931,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000031727,PMFBP1,polyamine modulated factor 1 binding protein 1,cytoplasm|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0225,0,0,0,0.905,0,0,-1.8,1
ENSMUSG00000043140,TMEM186,transmembrane protein 186,mitochondrion|mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,0.735,10,0,0,0,0,0,0.905,0,0,-1.5,1.4
ENSMUSG00000034472,RASD2,"RASD family, member 2",plasma membrane|membrane|,"synaptic transmission, dopaminergic|GTP catabolic process|signal transduction|small GTPase mediated signal transduction|behavior|locomotory behavior|locomotory behavior|negative regulation of protein ubiquitination|positive regulation of protein sumoylation|regulation of cAMP-mediated signaling|positive regulation of protein kinase B signaling|",nucleotide binding|GTP binding|ubiquitin conjugating enzyme binding|G-protein beta-subunit binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.4,1.7
ENSMUSG00000020308,TPGS1,tubulin polyglutamylase complex subunit 1,cytoplasm|centrosome|cytoskeleton|microtubule|cilium|integral component of membrane|cell projection|,synaptic transmission|multicellular organismal development|spermatogenesis|sperm axoneme assembly|protein polyglutamylation|cell differentiation|adult behavior|vesicle localization|,protein binding|microtubule binding|tubulin binding|tubulin-glutamic acid ligase activity|,10,0,0,10,-0.1,0.138,0,0,0,0.905,0,0,-1,1.9
ENSMUSG00000044456,RIN3,Ras and Rab interactor 3,cytoplasm|endosome|early endosome|cytoplasmic vesicle|,signal transduction|positive regulation of Rab GTPase activity|,GTPase activator activity|Rab guanyl-nucleotide exchange factor activity|Rab GTPase binding|,10,0,0,10,0.1,0.348,0,0,0,0.905,0,0,-2,1
ENSMUSG00000020598,NRCAM,neuronal cell adhesion molecule,plasma membrane|membrane|integral component of membrane|axon|axon initial segment|synapse|,cell adhesion|axon guidance|central nervous system development|protein localization|regulation of neuron projection development|single organismal cell-cell adhesion|neuronal action potential propagation|retinal ganglion cell axon guidance|heterotypic cell-cell adhesion|clustering of voltage-gated sodium channels|clustering of voltage-gated sodium channels|,protein binding|ankyrin binding|protein binding involved in heterotypic cell-cell adhesion|,10,-0.1,0.232,10,0.1,0.293,0,0,0,0.905,0,0,-1.5,1.4
ENSMUSG00000006958,CHRD,chordin,extracellular region|extracellular space|,skeletal system development|osteoblast differentiation|gastrulation with mouth forming second|mesoderm formation|positive regulation of mesenchymal cell proliferation|multicellular organismal development|pattern specification process|central nervous system development|dorsal/ventral pattern formation|BMP signaling pathway involved in spinal cord dorsal/ventral patterning|negative regulation of cell migration|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|forebrain development|negative regulation of osteoblast differentiation|negative regulation of osteoblast differentiation|positive regulation of cell adhesion|,protein binding|heparin binding|syndecan binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.7,1.4
ENSMUSG00000002100,MYBPC3,"myosin binding protein C, cardiac",cytoskeleton|striated muscle myosin thick filament|myofibril|sarcomere|sarcomere|A band|A band|myosin filament|,regulation of heart rate|heart morphogenesis|heart morphogenesis|muscle contraction|cell adhesion|regulation of heart contraction|myosin filament assembly|sarcomere organization|ventricular cardiac muscle tissue morphogenesis|cardiac muscle contraction|,actin binding|structural constituent of cytoskeleton|structural constituent of muscle|myosin binding|myosin heavy chain binding|myosin heavy chain binding|identical protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.5
ENSMUSG00000027483,BPIFA1,"BPI fold containing family A, member 1",extracellular region|extracellular space|microvillus|,immune system process|antibacterial humoral response|antibacterial humoral response|defense response to bacterium|innate immune response|innate immune response|regulation of liquid surface tension|multicellular organismal water homeostasis|negative regulation of single-species biofilm formation in or on host organism|negative regulation of single-species biofilm formation in or on host organism|regulation of sodium ion transmembrane transport|,lipid binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.7,1.4
ENSMUSG00000054474,THNSL2,threonine synthase-like 2 (bacterial),cellular_component|,serine family amino acid catabolic process|dephosphorylation|2-oxobutyrate biosynthetic process|,lyase activity|pyridoxal phosphate binding|(E)-beta-ocimene synthase activity|serine binding|sabinene synthase activity|(-)-E-beta-caryophyllene synthase activity|alpha-humulene synthase activity|,10,-0.1,0.0781,10,0,0,0,0,0,0.905,0,0,-1.8,1.1
ENSMUSG00000035478,MBD3,methyl-CpG binding domain protein 3,chromatin|nuclear chromatin|heterochromatin|nucleus|chromosome|cytoplasm|NuRD complex|protein complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|methylation-dependent chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|tissue development|histone acetylation|ATP-dependent chromatin remodeling|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|DNA binding|chromatin binding|protein binding|methyl-CpG binding|nucleosomal DNA binding|,10,0,0,10,0.4,0.631,0,0,0,0.905,0,0,-0.9,1.8
ENSMUSG00000024228,NUDT12,nudix (nucleoside diphosphate linked moiety X)-type motif 12,nucleus|cytoplasm|peroxisome|,NADP catabolic process|NAD catabolic process|,NAD+ diphosphatase activity|hydrolase activity|NADH pyrophosphatase activity|metal ion binding|,10,-0.1,0.151,10,0,0,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000005873,REEP5,receptor accessory protein 5,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,protein binding|,10,0.1,0.0784,10,0,0,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000030492,SLC7A9,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 9",plasma membrane|membrane|integral component of membrane|brush border membrane|brush border membrane|,amino acid transmembrane transport|transport|amino acid transport|,protein binding|amino acid transmembrane transporter activity|,10,-0.3,0.675,10,0.1,0.15,0,0,0,0.905,0,0,-1.5,1.3
ENSMUSG00000020495,SMG8,"smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)",cellular_component|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of protein kinase activity|",molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.4,1.7
ENSMUSG00000059430,ACTG2,"actin, gamma 2, smooth muscle, enteric",extracellular space|cytoplasm|cytoskeleton|cell periphery|blood microparticle|,None,nucleotide binding|ATP binding|,9,-0.5,0.619,9,0,0,0,0,0,0.905,0,0,-1.9,1.1
ENSMUSG00000061455,STX17,syntaxin 17,autophagic vacuole membrane|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum-Golgi intermediate compartment|cytosol|membrane|integral component of membrane|ER to Golgi transport vesicle|smooth endoplasmic reticulum membrane|SNARE complex|SNARE complex|cytoplasmic vesicle|ER-mitochondrion membrane contact site|,autophagic vacuole fusion|transport|intracellular protein transport|exocytosis|ER to Golgi vesicle-mediated transport|autophagy|Golgi organization|vesicle-mediated transport|protein localization to pre-autophagosomal structure|endoplasmic reticulum-Golgi intermediate compartment organization|,SNARE binding|SNARE binding|SNAP receptor activity|SNAP receptor activity|protein kinase binding|protein phosphatase binding|,10,0,0,10,0.5,2.3,0,0,0,0.905,0,0,-0.6,1.9
ENSMUSG00000054027,NT5DC3,5'-nucleotidase domain containing 3,mitochondrion|cytosol|receptor complex|,biological_process|,"molecular_function|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|metal ion binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0,0,10,0,0,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000053846,LIPG,"lipase, endothelial",extracellular region|extracellular space|,lipid metabolic process|cell proliferation|positive regulation of high-density lipoprotein particle clearance|lipid catabolic process|positive regulation of cholesterol transport|high-density lipoprotein particle remodeling|cholesterol homeostasis|reverse cholesterol transport|regulation of lipoprotein metabolic process|phospholipid homeostasis|,catalytic activity|lipoprotein lipase activity|phospholipase activity|triglyceride lipase activity|heparin binding|phosphatidylcholine 1-acylhydrolase activity|hydrolase activity|,10,0.1,0.249,10,0,0,0,0,0,0.905,0,0,-1.4,1.7
ENSMUSG00000021929,KPNA3,karyopherin (importin) alpha 3,nucleus|cytoplasm|,protein import into nucleus|transport|protein transport|,protein C-terminus binding|protein transporter activity|,10,0,0,10,-0.1,0.0679,0,0,0,0.905,0,0,-0.8,2
ENSMUSG00000010825,GRID2IP,"glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1",plasma membrane|membrane|cell junction|cell projection|dendritic spine|synapse|postsynaptic membrane|,G-protein coupled glutamate receptor signaling pathway|actin cytoskeleton organization|long term synaptic depression|,protein binding|,10,0,0,10,-0.2,0.338,0,0,0,0.905,0,0,-1.6,1.3
ENSMUSG00000042628,ZFYVE1,"zinc finger, FYVE domain containing 1",pre-autophagosomal structure|autophagic vacuole|endoplasmic reticulum|Golgi apparatus|Golgi stack|ER-mitochondrion membrane contact site|perinuclear region of cytoplasm|,negative regulation of phosphatase activity|,"1-phosphatidylinositol binding|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-3,4-bisphosphate binding|metal ion binding|",10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000007097,ATP1A2,"ATPase, Na+/K+ transporting, alpha 2 polypeptide",cytoplasm|endosome|plasma membrane|sodium:potassium-exchanging ATPase complex|caveola|membrane|integral component of membrane|T-tubule|T-tubule|sarcolemma|sarcolemma|neuron projection|dendritic spine|synapse|,neurotransmitter uptake|regulation of the force of heart contraction|regulation of respiratory gaseous exchange by neurological system process|ATP catabolic process|ATP biosynthetic process|transport|ion transport|cation transport|potassium ion transport|sodium ion transport|regulation of muscle contraction|regulation of smooth muscle contraction|regulation of striated muscle contraction|regulation of blood pressure|adult locomotory behavior|visual learning|monovalent inorganic cation transport|ATP hydrolysis coupled proton transport|regulation of vasoconstriction|regulation of vasoconstriction|response to nicotine|sodium ion transmembrane transport|locomotion|negative regulation of heart contraction|negative regulation of striated muscle contraction|negative regulation of cytosolic calcium ion concentration|cellular response to mechanical stimulus|potassium ion transmembrane transport|regulation of cardiac muscle cell contraction|,"nucleotide binding|sodium:potassium-exchanging ATPase activity|protein binding|ATP binding|monovalent inorganic cation transmembrane transporter activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|cation-transporting ATPase activity|metal ion binding|",10,0,0,10,1.1,0.851,0,0,0,0.905,0,0,-0.9,2
ENSMUSG00000022246,RAI14,retinoic acid induced 14,nucleus|cytoplasm|mitochondrion|cytoskeleton|actin cytoskeleton|,None,None,10,0,0,10,0.1,0.1,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000037681,ESYT3,extended synaptotagmin-like protein 3,endoplasmic reticulum|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|extrinsic component of cytoplasmic side of plasma membrane|organelle membrane contact site|,transport|lipid transport|biological_process|,molecular_function|lipid binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000020639,PFN4,"profilin family, member 4",cellular_component|cytoplasm|cytoskeleton|,biological_process|actin cytoskeleton organization|,actin binding|lipid binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.5
ENSMUSG00000064262,GIMAP8,"GTPase, IMAP family member 8",nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|,biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000039697,NCOA7,nuclear receptor coactivator 7,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",ligand-dependent nuclear receptor transcription coactivator activity|nuclear hormone receptor binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1,2
ENSMUSG00000030000,ADD2,adducin 2 (beta),cytoplasm|cytoskeleton|plasma membrane|F-actin capping protein complex|membrane|cytoplasmic membrane-bounded vesicle|,protein complex assembly|ion transport|hemopoiesis|positive regulation of protein binding|barbed-end actin filament capping|actin filament bundle assembly|,actin binding|structural molecule activity|calmodulin binding|spectrin binding|protein homodimerization activity|protein heterodimerization activity|actin filament binding|,10,0.2,0.0564,10,0,0,0,0,0,0.905,0,0,-1.1,1.9
ENSMUSG00000038388,MPP6,"membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,nucleotide phosphorylation|,guanylate kinase activity|protein binding|PDZ domain binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.2,1.9
ENSMUSG00000019986,AHI1,Abelson helper integration site 1,photoreceptor outer segment|cytoplasm|centrosome|centriole|cytoskeleton|cell-cell junction|adherens junction|cilium|cilium|cell junction|nonmotile primary cilium|TCTN-B9D complex|ciliary basal body|ciliary basal body|cell projection|primary cilium|,morphogenesis of a polarized epithelium|heart looping|positive regulation of receptor internalization|vesicle targeting|transmembrane receptor protein tyrosine kinase signaling pathway|central nervous system development|positive regulation of gene expression|retina layer formation|vesicle-mediated transport|cell projection organization|positive regulation of polarized epithelial cell differentiation|hindbrain development|protein localization to organelle|cellular protein localization|cloaca development|photoreceptor cell outer segment organization|photoreceptor cell outer segment organization|pronephric nephron tubule morphogenesis|cilium assembly|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|regulation of behavior|retina development in camera-type eye|cilium morphogenesis|specification of axis polarity|otic vesicle development|,protein binding|,10,0,0,10,0.1,0.117,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000022659,GCSAM,"germinal center associated, signaling and motility",cytoplasm|plasma membrane|membrane|,regulation of B cell receptor signaling pathway|negative regulation of lymphocyte migration|,actin binding|protein kinase binding|myosin II binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000033697,ARHGAP39,Rho GTPase activating protein 39,intracellular|nucleus|cytoskeleton|,signal transduction|,molecular_function|,10,0,0,10,0.1,0.227,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000067369,TRMT2B,TRM2 tRNA methyltransferase 2B,mitochondrion|,tRNA processing|biological_process|methylation|,methyltransferase activity|transferase activity|S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity|,10,0,0,10,-0.6,1.75,0,0,0,0.905,0,0,-1.9,1.3
ENSMUSG00000035559,MPV17L2,MPV17 mitochondrial membrane protein-like 2,mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.6,0.435,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000054052,RDH19,retinol dehydrogenase 19,cellular_component|,biological_process|,None,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000036892,PRODH2,proline dehydrogenase (oxidase) 2,mitochondrion|mitochondrial inner membrane|,proline metabolic process|proline catabolic process|oxidation-reduction process|,proline dehydrogenase activity|oxidoreductase activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000049439,CYP20A1,"cytochrome P450, family 20, subfamily a, polypeptide 1",membrane|membrane|integral component of membrane|,oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|fluorene oxygenase activity|mono-butyltin dioxygenase activity|tri-n-butyltin dioxygenase activity|di-n-butyltin dioxygenase activity|methylsilanetriol hydroxylase activity|methyl tertiary butyl ether 3-monooxygenase activity|4-nitrocatechol 4-monooxygenase activity|4-chlorophenoxyacetate monooxygenase activity|tert-butanol 2-monooxygenase activity|alpha-pinene monooxygenase activity|dimethylsilanediol hydroxylase activity|ammonia monooxygenase activity|hydroxymethylsilanetriol oxidase activity|2-hydroxyisobutyrate 3-monooxygenase activity|alpha-pinene dehydrogenase activity|heme binding|bisphenol A hydroxylase B activity|2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity|9-fluorenone-3,4-dioxygenase activity|anthracene 9,10-dioxygenase activity|2-(methylthio)benzothiazole monooxygenase activity|2-hydroxybenzothiazole monooxygenase activity|benzothiazole monooxygenase activity|2,6-dihydroxybenzothiazole monooxygenase activity|pinacolone 5-monooxygenase activity|thioacetamide S-oxygenase activity|thioacetamide S-oxide S-oxygenase activity|endosulfan monooxygenase I activity|N-nitrodimethylamine hydroxylase activity|4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity|endosulfan ether monooxygenase activity|pyrene 4,5-monooxygenase activity|pyrene 1,2-monooxygenase activity|1-hydroxypyrene 6,7-monooxygenase activity|1-hydroxypyrene 7,8-monooxygenase activity|phenylboronic acid monooxygenase activity|spheroidene monooxygenase activity|metal ion binding|",10,0,0,10,0,0,0,0,0,0.905,0,0,-1.2,1.7
ENSMUSG00000015943,BOLA1,bolA-like 1 (E. coli),extracellular region|mitochondrion|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0106,0,0,0,0.905,0,0,-1.2,1.8
ENSMUSG00000022026,OLFM4,olfactomedin 4,extracellular region|extracellular space|extracellular space|mitochondrion|plasma membrane|specific granule|perinuclear region of cytoplasm|extracellular vesicular exosome|,cell adhesion|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of immune response|protein homooligomerization|positive regulation of substrate adhesion-dependent cell spreading|,protein binding|protein homodimerization activity|cadherin binding|,10,0,0,10,0.8,2.77,0,0,0,0.905,0,0,-1,2
ENSMUSG00000032892,RANGRF,RAN guanine nucleotide release factor,intracellular|cell|nucleus|nucleoplasm|cytoplasm|rough endoplasmic reticulum|caveola|intercalated disc|,regulation of membrane depolarization|regulation of membrane depolarization|transport|ER to Golgi vesicle-mediated transport|nucleocytoplasmic transport|protein transport|protein exit from endoplasmic reticulum|regulation of membrane potential|positive regulation of GTPase activity|positive regulation of establishment of protein localization to plasma membrane|regulation of sodium ion transmembrane transport|regulation of sodium ion transmembrane transport|positive regulation of protein localization to cell surface|regulation of sodium ion transmembrane transporter activity|regulation of sodium ion transmembrane transporter activity|,guanyl-nucleotide exchange factor activity|Ran GTPase binding|Ran GTPase binding|protein transporter activity|sodium channel regulator activity|sodium channel regulator activity|ion channel binding|ion channel binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.1,2
ENSMUSG00000052681,RAP1B,RAS related protein 1b,intracellular|intracellular|cytoplasm|lipid particle|plasma membrane|cell-cell junction|membrane|cell junction|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|cell proliferation|Rap protein signal transduction|negative regulation of calcium ion-dependent exocytosis|establishment of endothelial barrier|positive regulation of ERK1 and ERK2 cascade|cellular response to cAMP|regulation of cell junction assembly|regulation of establishment of cell polarity|negative regulation of synaptic vesicle exocytosis|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|protein complex binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.5
ENSMUSG00000067614,KRT86,keratin 86,extracellular space|intermediate filament|keratin filament|extracellular vesicular exosome|,None,structural molecule activity|,10,0,0,9,0,0,0,0,0,0.905,0,0,-1.4,1.7
ENSMUSG00000034675,DBN1,drebrin 1,intracellular|cell|cytoplasm|plasma membrane|cell-cell junction|gap junction|actin cytoskeleton|membrane|cell junction|,actin filament organization|multicellular organismal development|nervous system development|cell communication by chemical coupling|cell communication by electrical coupling|cell differentiation|maintenance of protein location in cell|,actin binding|protein binding|profilin binding|,10,0,0,10,-0.3,0.589,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000020775,MRPL38,mitochondrial ribosomal protein L38,mitochondrion|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,10,-0.1,0.6,10,0.1,0.308,0,0,0,0.905,0,0,-1.3,1.6
ENSMUSG00000055748,GSDMC4,gasdermin C4,cytoplasm|mitochondrion|microtubule organizing center|,biological_process|,molecular_function|,10,0.2,0.223,10,0,0,0,0,0,0.905,0,0,-1.2,1.7
ENSMUSG00000025036,SFXN2,sideroflexin 2,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|biological_process|iron ion homeostasis|transmembrane transport|,molecular_function|cation transmembrane transporter activity|,10,0,0,10,0.6,0.136,0,0,0,0.905,0,0,-1,2
ENSMUSG00000022973,SYNJ1,synaptojanin 1,cell|cytoplasm|membrane coat|clathrin coat|neuron projection|protein complex|,neurotransmitter transport|learning|positive regulation of gliogenesis|synaptic vesicle priming|synaptic vesicle uncoating|dephosphorylation|response to retinoic acid|response to cytokine|phosphatidylinositol metabolic process|phosphatidylinositol metabolic process|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|phosphatidylinositol-mediated signaling|positive regulation of receptor-mediated endocytosis|synaptic vesicle endocytosis|synaptic vesicle transport|,"phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|protein binding|protein C-terminus binding|SH3 domain binding|protein complex binding|phosphatidylinositol phosphate 5-phosphatase activity|phosphatidylinositol phosphate 5-phosphatase activity|",10,0,0,10,0,0,0,0,0,0.905,0,0,-1,1.9
ENSMUSG00000026417,PIGR,polymeric immunoglobulin receptor,extracellular region|extracellular space|plasma membrane|membrane|integral component of membrane|transport vesicle|receptor complex|recycling endosome membrane|extracellular vesicular exosome|,detection of chemical stimulus involved in sensory perception of bitter taste|immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor|epidermal growth factor receptor signaling pathway|Fc receptor signaling pathway|receptor clustering|,polymeric immunoglobulin receptor activity|epidermal growth factor receptor binding|,10,0,0,10,-0.1,0.0559,0,0,0,0.905,0,0,-1.4,1.8
ENSMUSG00000074628,TLDC2,TBC/LysM associated domain containing 2,cellular_component|,biological_process|,molecular_function|,9,0.1,0.0559,9,0,0,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000022022,MTRF1,mitochondrial translational release factor 1,cytoplasm|mitochondrion|,translation|translational termination|,"molecular_function|translation release factor activity|translation release factor activity, codon specific|",10,0,0,10,0.3,1.19,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000039114,NRN1,neuritin 1,plasma membrane|membrane|cell junction|anchored component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|,nervous system development|axonogenesis|,None,10,0,0,10,-0.2,0.636,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000024049,MYOM1,myomesin 1,cytoplasm|cytoskeleton|sarcomere|M band|myosin filament|,muscle contraction|,structural constituent of cytoskeleton|identical protein binding|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000091251,KISS1,KiSS-1 metastasis-suppressor,extracellular space|cytoplasm|apical plasma membrane|neuron projection|neuronal cell body|,G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell migration|positive regulation of luteinizing hormone secretion|positive regulation of MAPK cascade|positive regulation of synaptic transmission|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|generation of ovulation cycle rhythm|positive regulation of growth hormone secretion|,G-protein coupled receptor binding|protein binding|kisspeptin receptor binding|,10,0.1,0.362,10,0,0,0,0,0,0.905,0,0,-1.2,1.8
ENSMUSG00000027378,NPHP1,nephronophthisis 1 (juvenile) homolog (human),cytoplasm|cytoskeleton|cell-cell junction|tight junction|cilium|cell junction|motile cilium|photoreceptor connecting cilium|ciliary transition zone|cell projection|,spermatogenesis|cell projection organization|cell differentiation|cellular protein localization|photoreceptor cell outer segment organization|spermatid differentiation|retina development in camera-type eye|,protein binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.2,1.7
ENSMUSG00000002781,TMEM143,transmembrane protein 143,mitochondrion|mitochondrion|membrane|integral component of membrane|,hematopoietic progenitor cell differentiation|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.2,1.9
ENSMUSG00000090700,CYP4F40,"cytochrome P450, family 4, subfamily f, polypeptide 40",cellular_component|,oxidation-reduction process|,monooxygenase activity|oxidoreductase activity|metal ion binding|,10,0,0,10,0.2,0.555,0,0,0,0.905,0,0,-1.4,1.5
ENSMUSG00000024846,CST6,cystatin E/M,cornified envelope|extracellular vesicular exosome|,epidermis development|negative regulation of peptidase activity|,cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000031160,ERAS,ES cell-expressed Ras,cellular_component|plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0,0,10,-0.2,0.553,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000050370,CH25H,cholesterol 25-hydroxylase,endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid biosynthetic process|steroid biosynthetic process|steroid metabolic process|cholesterol metabolic process|sterol biosynthetic process|oxidation-reduction process|,cholesterol 25-hydroxylase activity|monooxygenase activity|iron ion binding|steroid hydroxylase activity|oxidoreductase activity|metal ion binding|,10,0.1,0.157,10,0,0,0,0,0,0.905,0,0,-1.3,1.7
ENSMUSG00000022208,JPH4,junctophilin 4,endoplasmic reticulum|smooth endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|dendritic shaft|,learning|regulation of synaptic plasticity|neuromuscular process controlling balance|,molecular_function|,10,-0.3,0.25,10,0.1,0.129,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000042678,MYO15,myosin XV,cytoplasm|cytoskeleton|myosin complex|stereocilium|stereocilium bundle|cell projection|extracellular vesicular exosome|,sensory perception of sound|locomotory behavior|inner ear morphogenesis|,nucleotide binding|motor activity|actin binding|protein binding|ATP binding|,10,0,0,10,0.4,0.79,0,0,0,0.905,0,0,-1.4,1.5
ENSMUSG00000063406,TMED5,transmembrane emp24 protein transport domain containing 5,endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|cis-Golgi network|membrane|integral component of membrane|endoplasmic reticulum exit site|,transport|protein transport|Golgi ribbon formation|,molecular_function|,10,-0.1,0.397,10,0,0,0,0,0,0.905,0,0,-1.2,1.8
ENSMUSG00000061273,MMGT1,membrane magnesium transporter 1,cytoplasm|endosome|early endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|ER membrane protein complex|,transport|cation transport|cobalt ion transport|copper ion transport|ferrous iron transport|magnesium ion transport|iron ion transmembrane transport|,cobalt ion transmembrane transporter activity|ferrous iron transmembrane transporter activity|magnesium ion transmembrane transporter activity|inorganic cation transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.4
ENSMUSG00000036853,MCOLN3,mucolipin 3,cytoplasm|plasma membrane|membrane|integral component of membrane|,transport|ion transport|sensory perception of sound|locomotory behavior|auditory receptor cell differentiation|,None,10,0.3,0.645,10,-1,0.951,0,0,0,0.905,0,0,-2,1
ENSMUSG00000069456,RDH16,retinol dehydrogenase 16,endoplasmic reticulum lumen|integral component of organelle membrane|,9-cis-retinoic acid biosynthetic process|oxidation-reduction process|,retinol dehydrogenase activity|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000035863,PALM,paralemmin,nucleus|cytoplasm|plasma membrane|plasma membrane|membrane|basolateral plasma membrane|apicolateral plasma membrane|filopodium|axon|filopodium membrane|dendrite membrane|dendritic spine membrane|cell projection|neuron spine|,cytoskeleton organization|negative regulation of adenylate cyclase activity|negative regulation of adenylate cyclase activity|protein localization|regulation of cell shape|negative regulation of cAMP biosynthetic process|positive regulation of filopodium assembly|positive regulation of filopodium assembly|synapse maturation|negative regulation of dopamine receptor signaling pathway|positive regulation of dendritic spine development|cellular response to electrical stimulus|protein targeting to plasma membrane|,D3 dopamine receptor binding|,10,0,0,10,0.1,0.042,0,0,0,0.905,0,0,-1.3,1.8
ENSMUSG00000091043,GLYATL3,glycine-N-acyltransferase-like 3,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.6,1.5
ENSMUSG00000046329,SLC25A23,"solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,regulation of oxidative phosphorylation|transport|regulation of cellular respiration|regulation of sequestering of calcium ion|adenine nucleotide transport|transmembrane transport|cellular response to calcium ion|urea homeostasis|,calcium ion binding|metal ion binding|,10,0.1,0.276,10,0,0,0,0,0,0.905,0,0,-1.4,1.6
ENSMUSG00000029769,CCDC136,coiled-coil domain containing 136,mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.9,1.1
ENSMUSG00000022108,ITM2B,integral membrane protein 2B,extracellular region|extracellular space|endosome|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|Golgi-associated vesicle membrane|integral component of organelle membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,negative regulation of amyloid precursor protein biosynthetic process|extrinsic apoptotic signaling pathway in absence of ligand|extrinsic apoptotic signaling pathway in absence of ligand|,beta-amyloid binding|protein binding|ATP binding|,10,0,0,10,-0.1,0.224,0,0,0,0.905,0,0,-1.7,1.3
ENSMUSG00000022808,SNX4,sorting nexin 4,cytoplasm|endosome|cytoplasmic dynein complex|membrane|early endosome membrane|,transport|intracellular protein transport|protein transport|endocytic recycling|,lipid binding|phosphatidylinositol binding|phosphatidylinositol binding|,10,0,0,10,-0.3,1.53,0,0,0,0.905,0,0,-1.7,1.1
ENSMUSG00000090698,APOLD1,apolipoprotein L domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.567,10,0.3,0.916,0,0,0,0.905,0,0,-1.2,1.6
ENSMUSG00000024259,SLC25A46,"solute carrier family 25, member 46",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0,0,10,-0.1,0.00213,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000037243,ZFP692,zinc finger protein 692,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000070939,TGFBRAP1,"transforming growth factor, beta receptor associated protein 1",cytoplasm|membrane|,"regulation of transcription, DNA-templated|intracellular protein transport|signal transduction|vesicle-mediated transport|",small GTPase regulator activity|transforming growth factor beta receptor binding|SMAD binding|,9,0,0,10,0.3,1.04,0,0,0,0.905,0,0,-0.7,2
ENSMUSG00000056656,APOL8,apolipoprotein L 8,membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.5
ENSMUSG00000048616,NOG,noggin,extracellular region|extracellular space|extracellular space|,negative regulation of transcription from RNA polymerase II promoter|skeletal system development|osteoblast differentiation|urogenital system development|ureteric bud development|in utero embryonic development|endoderm formation|mesoderm formation|epithelial to mesenchymal transition|neural plate morphogenesis|neural tube closure|multicellular organismal development|pattern specification process|axon guidance|central nervous system development|brain development|motor neuron axon guidance|dorsal/ventral pattern formation|negative regulation of gene expression|spinal cord development|cell differentiation in hindbrain|neural tube development|pituitary gland development|cell differentiation|negative regulation of cell migration|BMP signaling pathway|regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|somatic stem cell maintenance|wound healing|middle ear morphogenesis|embryonic digit morphogenesis|negative regulation of cell differentiation|regulation of neuron differentiation|negative regulation of osteoblast differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|axial mesoderm development|notochord morphogenesis|anatomical structure formation involved in morphogenesis|anatomical structure formation involved in morphogenesis|embryonic skeletal system development|negative regulation of astrocyte differentiation|negative regulation of astrocyte differentiation|mesenchymal cell differentiation|positive regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|cartilage development|negative regulation of cardiac muscle cell proliferation|limb development|embryonic skeletal joint morphogenesis|negative regulation of cytokine activity|face morphogenesis|negative regulation of pathway-restricted SMAD protein phosphorylation|lung morphogenesis|prostatic bud formation|ureteric bud formation|fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation|negative regulation of cartilage development|somite development|cellular response to BMP stimulus|negative regulation of canonical Wnt signaling pathway|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of glomerulus development|regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation|negative regulation of apoptotic signaling pathway|,cytokine binding|protein complex binding|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.905,0,0,-1.5,1.6
ENSMUSG00000037787,APOPT1,"apoptogenic, mitochondrial 1",mitochondrion|,apoptotic process|positive regulation of smooth muscle cell apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of release of cytochrome c from mitochondria|intrinsic apoptotic signaling pathway|,molecular_function|,9,0,0,9,-0.3,0.922,0,0,0,0.905,0,0,-2,0.9
ENSMUSG00000027377,MALL,"mal, T cell differentiation protein-like",Golgi membrane|plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|clathrin-coated vesicle|membrane raft|,biological_process|,molecular_function|,10,-0.1,0.195,10,0.2,1.15,0,0,0,0.905,0,0,-1.8,1
ENSMUSG00000029713,GNB2,"guanine nucleotide binding protein (G protein), beta 2",extracellular space|cytoplasm|lysosomal membrane|heterotrimeric G-protein complex|membrane|protein complex|cell body|perinuclear region of cytoplasm|extracellular vesicular exosome|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|,GTPase activity|signal transducer activity|calcium channel regulator activity|protein binding|protein complex binding|GTPase binding|,10,5.8,278,10,6,278,5.9,555,555,1.00E-05,1,1,5.6,7
ENSMUSG00000030341,TNFRSF1A,"tumor necrosis factor receptor superfamily, member 1a",Golgi membrane|extracellular space|intracellular|nucleus|mitochondrion|Golgi apparatus|cytosol|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|axon|protein complex|receptor complex|membrane raft|membrane raft|synapse|,"prostaglandin metabolic process|apoptotic process|defense response|inflammatory response|signal transduction|cell surface receptor signaling pathway|intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of gene expression|negative regulation of gene expression|programmed cell death|cytokine-mediated signaling pathway|negative regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of protein import into nucleus, translocation|tumor necrosis factor-mediated signaling pathway|tumor necrosis factor-mediated signaling pathway|positive regulation of tyrosine phosphorylation of Stat1 protein|defense response to bacterium|regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of inflammatory response|positive regulation of inflammatory response|protein heterooligomerization|",protease binding|tumor necrosis factor-activated receptor activity|tumor necrosis factor-activated receptor activity|tumor necrosis factor-activated receptor activity|tumor necrosis factor-activated receptor activity|protein binding|protein complex binding|tumor necrosis factor binding|,10,2.8,218,10,2.4,147,2.6,363,363,1.00E-05,1,1,2.3,3.3
ENSMUSG00000011960,CCNT1,cyclin T1,nucleus|nucleus|positive transcription elongation factor complex b|positive transcription elongation factor complex b|,"regulation of cyclin-dependent protein serine/threonine kinase activity|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|cell cycle|cell division|",DNA binding|chromatin binding|protein binding|snRNA binding|protein kinase binding|transcription regulatory region DNA binding|,10,3,172,10,3.7,147,3.3,317,317,1.00E-05,1,1,2.9,4.2
ENSMUSG00000033220,RAC2,RAS-related C3 botulinum substrate 2,intracellular|nuclear envelope|cytoplasm|membrane|extracellular vesicular exosome|,GTP catabolic process|chemotaxis|G-protein coupled receptor signaling pathway|small GTPase mediated signal transduction|positive regulation of cell proliferation|positive regulation of cell proliferation|cell projection assembly|actin cytoskeleton organization|actin cytoskeleton organization|bone resorption|regulation of respiratory burst|,nucleotide binding|GTPase activity|GTP binding|,9,2.9,76.3,9,3.2,113,3,189,189,1.00E-05,1,1,2.4,3.8
ENSMUSG00000060126,TPT1,"tumor protein, translationally-controlled 1",extracellular space|nucleus|nucleoplasm|cytoplasm|multivesicular body|tubulin complex|,stem cell maintenance|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of ectoderm development|,calcium ion binding|transcription factor binding|poly(A) RNA binding|,10,2.1,117,10,3.3,64.4,2.6,178,178,1.00E-05,1,1,2,3.6
ENSMUSG00000022565,PLEC,plectin,cytoplasm|cytoskeleton|focal adhesion|basal plasma membrane|apical plasma membrane|sarcoplasm|cell junction|hemidesmosome|sarcolemma|contractile fiber|intermediate filament cytoskeleton|perinuclear region of cytoplasm|extracellular vesicular exosome|,response to nutrient|hemidesmosome assembly|,actin binding|structural constituent of cytoskeleton|protein binding|cytoskeletal protein binding|structural constituent of muscle|ankyrin binding|poly(A) RNA binding|protein N-terminus binding|,10,2.4,93.2,10,2.1,71.1,2.4,163,163,1.00E-05,1,1,1.9,3
ENSMUSG00000031887,TRADD,TNFRSF1A-associated via death domain,nucleus|cytoplasm|cytoplasm|cytoskeleton|protein complex|receptor complex|membrane raft|,apoptotic process|signal transduction|regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|protein heterooligomerization|positive regulation of hair follicle development|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway|,"signal transducer activity|tumor necrosis factor receptor binding|protein binding|kinase binding|protein complex binding|identical protein binding|binding, bridging|death domain binding|",10,2.3,89,10,1.6,61.6,1.9,148,148,1.00E-05,1,1,1.6,2.7
ENSMUSG00000020644,ID2,inhibitor of DNA binding 2,chromatin|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|centrosome|cytosol|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|metanephros development|natural killer cell differentiation|natural killer cell differentiation|leukocyte differentiation|membranous septum morphogenesis|bundle of His development|multicellular organismal development|heart development|positive regulation of cell proliferation|entrainment of circadian clock|positive regulation of gene expression|negative regulation of gene expression|negative regulation of gene expression|oligodendrocyte development|regulation of lipid metabolic process|olfactory bulb development|circadian regulation of gene expression|mammary gland epithelial cell proliferation|regulation of circadian rhythm|entrainment of circadian clock by photoperiod|enucleate erythrocyte differentiation|negative regulation of DNA binding|negative regulation of sequence-specific DNA binding transcription factor activity|locomotor rhythm|negative regulation of B cell differentiation|positive regulation of fat cell differentiation|positive regulation of erythrocyte differentiation|positive regulation of macrophage differentiation|negative regulation of neuron differentiation|negative regulation of osteoblast differentiation|positive regulation of blood pressure|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|cell development|cell maturation|lymph node development|Peyer's patch development|embryonic digestive tract morphogenesis|positive regulation of smooth muscle cell proliferation|neuron fate commitment|positive regulation of astrocyte differentiation|negative regulation of oligodendrocyte differentiation|adipose tissue development|mammary gland alveolus development|epithelial cell differentiation involved in mammary gland alveolus development|positive regulation of cell cycle arrest|cellular response to lithium ion|cellular senescence|regulation of G1/S transition of mitotic cell cycle|negative regulation of neural precursor cell proliferation|",protein binding|ion channel binding|protein dimerization activity|,10,1.9,82,10,1.7,57.1,1.8,138,138,1.00E-05,1,1,1.5,2.4
ENSMUSG00000029202,PDS5A,"PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)",chromatin|nucleus|plasma membrane|,negative regulation of DNA replication|,None,10,2.7,67.3,10,2.2,68.2,2.3,134,134,1.00E-05,1,1,1.8,3.1
ENSMUSG00000026219,TRIP12,thyroid hormone receptor interactor 12,nucleus|nucleus|nucleoplasm|cytoplasm|,DNA repair|cellular response to DNA damage stimulus|embryo development|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of histone H2A K63-linked ubiquitination|negative regulation of double-strand break repair|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|thyroid hormone receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,2.3,68.2,10,2.5,57.7,2.3,125,125,1.00E-05,1,1,1.7,3
ENSMUSG00000024974,SMC3,structural maintenance of chromosomes 3,"chromosome, centromeric region|chromatin|lateral element|spindle pole|basement membrane|nucleus|nucleus|chromosome|cytoplasm|nuclear matrix|meiotic cohesin complex|meiotic cohesin complex|nuclear meiotic cohesin complex|",regulation of DNA replication|DNA repair|cellular response to DNA damage stimulus|cell cycle|sister chromatid cohesion|mitotic nuclear division|meiotic nuclear division|meiotic nuclear division|signal transduction|stem cell maintenance|negative regulation of DNA endoreduplication|chromosome organization|cell division|,nucleotide binding|chromatin binding|protein binding|ATP binding|mediator complex binding|dynein binding|protein heterodimerization activity|,8,2.4,68.7,8,2.3,55.9,2.4,124,124,1.00E-05,1,1,1.8,3.2
ENSMUSG00000030057,CNBP,cellular nucleic acid binding protein,nucleus|cytoplasm|endoplasmic reticulum|cytosol|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|single-stranded DNA binding|single-stranded RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,1.9,53.8,10,2.6,69.5,1.9,123,123,1.00E-05,1,1,1.4,2.8
ENSMUSG00000071078,NR2C2AP,nuclear receptor 2C2-associated protein,nucleus|extracellular vesicular exosome|,cell adhesion|biological_process|,molecular_function|,10,3.6,57.6,10,2.7,67.2,2.1,122,122,1.00E-05,1,1,2,4
ENSMUSG00000035845,ALG12,"asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,protein N-linked glycosylation|dolichol-linked oligosaccharide biosynthetic process|mannosylation|,"mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity|",10,1.5,43.4,10,1.7,66.8,1.6,109,109,1.00E-05,1,1,1.3,2.4
ENSMUSG00000022141,NIPBL,Nipped-B homolog (Drosophila),chromatin|nucleus|SMC loading complex|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|heart morphogenesis|outflow tract morphogenesis|cellular response to DNA damage stimulus|cell cycle|mitotic sister chromatid cohesion|brain development|heart development|sensory perception of sound|stem cell maintenance|positive regulation of histone deacetylation|maintenance of mitotic sister chromatid cohesion|cellular protein localization|embryonic forelimb morphogenesis|forelimb morphogenesis|external genitalia morphogenesis|positive regulation of multicellular organism growth|ear morphogenesis|regulation of hair cycle|fat cell differentiation|positive regulation of ossification|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of embryonic development|embryonic digestive tract morphogenesis|developmental growth|eye morphogenesis|regulation of developmental growth|embryonic cranial skeleton morphogenesis|embryonic viscerocranium morphogenesis|cognition|face morphogenesis|gall bladder development|uterus morphogenesis|cellular response to X-ray|",chromatin binding|protein C-terminus binding|mediator complex binding|histone deacetylase binding|protein N-terminus binding|chromo shadow domain binding|,10,1.9,51.5,10,1.5,52.7,1.8,103,103,1.00E-05,1,1,1.2,2.3
ENSMUSG00000030199,ETV6,ets variant 6,nucleus|nucleolus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein domain specific binding|sequence-specific DNA binding|,10,1.5,42.5,10,1.3,49.4,1.4,91.2,91.2,1.00E-05,1,1,1.1,1.9
ENSMUSG00000031858,MAU2,MAU2 chromatid cohesion factor homolog (C. elegans),chromatin|chromatin|nucleus|nucleoplasm|SMC loading complex|,cell cycle|chromosome segregation|mitotic nuclear division|maintenance of mitotic sister chromatid cohesion|cell division|,protein N-terminus binding|,10,1.3,32.2,10,1.7,58.5,1.6,89.3,89.3,1.00E-05,1,1,1.3,2.4
ENSMUSG00000040459,ARGLU1,arginine and glutamate rich 1,nucleus|mitochondrion|,biological_process|,molecular_function|,9,1,26.6,9,2.4,58,1.8,79.4,79.4,1.00E-05,1,1,1.3,2.7
ENSMUSG00000031885,CBFB,core binding factor beta,nucleus|membrane|,ossification|osteoblast differentiation|lymphocyte differentiation|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|cell maturation|definitive hemopoiesis|,DNA binding|transcription coactivator activity|protein binding|,9,2.2,55.2,10,1.3,24.7,1.7,76.1,76.1,1.00E-05,1,1,1.2,2.6
ENSMUSG00000050552,LAMTOR4,"late endosomal/lysosomal adaptor, MAPK and MTOR activator 4",lysosome|intracellular membrane-bounded organelle|Ragulator complex|,regulation of cell size|positive regulation of TOR signaling|positive regulation of GTPase activity|protein localization to lysosome|cellular response to amino acid stimulus|,guanyl-nucleotide exchange factor activity|protein complex scaffold|,10,1.7,40.6,10,1.8,35.9,1.8,76,76,1.00E-05,1,1,1.4,2.3
ENSMUSG00000055024,EP300,E1A binding protein p300,histone acetyltransferase complex|chromatin|nucleus|nucleus|transcription factor complex|cytoplasm|protein-DNA complex|,"negative regulation of transcription from RNA polymerase II promoter|response to hypoxia|response to hypoxia|somitogenesis|positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|internal protein amino acid acetylation|apoptotic process|apoptotic process|cell cycle|heart development|skeletal muscle tissue development|circadian rhythm|response to glucose|organ morphogenesis|positive regulation of glycoprotein biosynthetic process|positive regulation of gene expression|positive regulation of cell death|positive regulation of muscle atrophy|histone acetylation|N-terminal peptidyl-lysine acetylation|N-terminal peptidyl-lysine acetylation|internal peptidyl-lysine acetylation|cell differentiation|positive regulation of cell growth|lung development|negative regulation of cellular metabolic process|positive regulation of cellular metabolic process|positive regulation of protein binding|positive regulation of collagen biosynthetic process|positive regulation of protein import into nucleus, translocation|response to drug|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of DNA binding|protein kinase B signaling|response to estrogen|positive regulation by host of viral transcription|histone H3 acetylation|histone H4 acetylation|histone H4 acetylation|histone H2B acetylation|positive regulation of translation|positive regulation of axon extension|positive regulation of cell size|positive regulation of proteolysis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|positive regulation of protein secretion|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|cartilage development|response to calcium ion|regulation of angiotensin metabolic process|positive regulation of sarcomere organization|negative regulation of cell death|regulation of androgen receptor signaling pathway|protein-DNA complex assembly|response to dexamethasone|regulation of tubulin deacetylation|positive regulation of protein acetylation|negative regulation of miRNA metabolic process|regulation of RNA biosynthetic process|","RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|core promoter binding|RNA polymerase II transcription factor binding|RNA polymerase II activating transcription factor binding|RNA polymerase II activating transcription factor binding|core promoter proximal region DNA binding|p53 binding|p53 binding|DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription cofactor activity|transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|antigen binding|histone acetyltransferase activity|histone acetyltransferase activity|lysine N-acetyltransferase activity|protein binding|beta-catenin binding|transcription factor binding|transcription factor binding|zinc ion binding|acetyltransferase activity|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein kinase binding|chromatin DNA binding|chromatin DNA binding|protein complex binding|activating transcription factor binding|nuclear hormone receptor binding|glucocorticoid receptor binding|peroxisome proliferator activated receptor binding|bHLH transcription factor binding|SMAD binding|metal ion binding|androgen receptor binding|mitogen-activated protein kinase binding|NF-kappaB binding|pre-mRNA intronic binding|",10,1.9,33.1,10,2,41.3,1.9,74,74,1.00E-05,1,1,1.4,2.6
ENSMUSG00000028086,FBXW7,F-box and WD-40 domain protein 7,nucleus|nucleus|nucleoplasm|cytoplasm|endoplasmic reticulum|Golgi apparatus|SCF ubiquitin ligase complex|protein complex|perinuclear region of cytoplasm|,"vasculogenesis|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|sister chromatid cohesion|Notch signaling pathway|protein ubiquitination|protein ubiquitination|lung development|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|negative regulation of DNA endoreduplication|cellular response to UV|positive regulation of epidermal growth factor-activated receptor activity|protein stabilization|positive regulation of ERK1 and ERK2 cascade|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|",sequence-specific DNA binding transcription factor activity|protein binding|identical protein binding|,10,1.7,57.6,10,0.9,18.6,1.5,72.2,72.2,2.00E-05,1,1,1.2,2
ENSMUSG00000063953,AMD2,S-adenosylmethionine decarboxylase 2,cytosol|,polyamine biosynthetic process|spermidine biosynthetic process|,adenosylmethionine decarboxylase activity|adenosylmethionine decarboxylase activity|lyase activity|carboxy-lyase activity|putrescine binding|,8,1.8,28.5,8,2.7,41.1,2.5,67.1,67.1,3.00E-05,1,1,1.8,3.8
ENSMUSG00000022521,CREBBP,CREB binding protein,histone acetyltransferase complex|nuclear chromatin|nuclear chromatin|condensed chromosome outer kinetochore|nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|nuclear body|PML body|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell proliferation|histone acetylation|histone acetylation|N-terminal peptidyl-lysine acetylation|germ-line stem cell maintenance|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of G1/S transition of mitotic cell cycle|","core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|p53 binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription cofactor activity|transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|histone acetyltransferase activity|histone acetyltransferase activity|protein binding|transcription factor binding|transcription factor binding|zinc ion binding|acetyltransferase activity|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|activating transcription factor binding|peroxisome proliferator activated receptor binding|MRF binding|SMAD binding|metal ion binding|",10,1.6,33.4,10,1.4,33.4,1.6,65.8,65.8,6.00E-05,1,1,1.2,2.1
ENSMUSG00000022952,RUNX1,runt related transcription factor 1,basement membrane|nucleus|nucleus|,"skeletal system development|in utero embryonic development|liver development|myeloid progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|central nervous system development|regulation of signal transduction|hemopoiesis|hemopoiesis|myeloid cell differentiation|neuron differentiation|negative regulation of granulocyte differentiation|positive regulation of granulocyte differentiation|hair follicle morphogenesis|response to retinoic acid|embryonic hemopoiesis|positive regulation of angiogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|behavioral response to pain|neuron development|definitive hemopoiesis|regulation of hair follicle cell proliferation|cellular response to transforming growth factor beta stimulus|positive regulation of progesterone secretion|",regulatory region DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|calcium ion binding|protein binding|ATP binding|transcription factor binding|protein homodimerization activity|protein heterodimerization activity|repressing transcription factor binding|,7,1.7,27.7,8,2.7,39.5,2.1,64.6,64.6,8.00E-05,1,1,1.4,3.4
ENSMUSG00000024947,MEN1,multiple endocrine neoplasia 1,chromatin|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|nuclear matrix|cleavage furrow|histone methyltransferase complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|ossification|leukocyte homeostasis|negative regulation of protein phosphorylation|osteoblast fate commitment|osteoblast development|osteoblast development|chromatin remodeling|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle arrest|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|response to UV|embryo development|response to gamma radiation|chromatin modification|histone methylation|hemopoiesis|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of histone methylation|positive regulation of protein binding|regulation of activin receptor signaling pathway|histone lysine methylation|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of cell differentiation|negative regulation of osteoblast differentiation|negative regulation of osteoblast differentiation|negative regulation of osteoblast differentiation|positive regulation of osteoblast differentiation|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of JNK cascade|negative regulation of organ growth|embryonic skeletal system morphogenesis|positive regulation of cell division|negative regulation of telomerase activity|palate development|maternal process involved in female pregnancy|","four-way junction DNA binding|Y-form DNA binding|DNA binding|chromatin binding|double-stranded DNA binding|protein binding|histone-lysine N-methyltransferase activity|protein binding, bridging|sequence-specific DNA binding|transcription regulatory region DNA binding|protein N-terminus binding|R-SMAD binding|",10,-1.8,39.9,10,-0.9,25.3,-1,63.3,-63.3,8.00E-05,1,1,-1.9,-0.6
ENSMUSG00000002812,FLII,flightless I homolog (Drosophila),nucleus|cytoplasm|microtubule organizing center|cytoskeleton|cell junction|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|actin cytoskeleton organization|actin filament severing|",actin binding|protein binding|,10,2,40.1,10,1.8,23.5,1.8,62.7,62.7,9.00E-05,1,1,1.1,2.5
ENSMUSG00000069833,AHNAK,AHNAK nucleoprotein (desmoyokin),nucleus|cytoplasm|lysosomal membrane|cytosol|plasma membrane|plasma membrane|cell-cell junction|actin cytoskeleton|actin cytoskeleton|membrane|T-tubule|vesicle|vesicle|sarcolemma|costamere|cell-cell contact zone|cell-cell contact zone|membrane raft|membrane raft|extracellular vesicular exosome|,regulation of RNA splicing|protein oligomerization|regulation of voltage-gated calcium channel activity|,S100 protein binding|poly(A) RNA binding|structural molecule activity conferring elasticity|,10,1.5,35.6,10,1,28.1,1.4,62.6,62.6,9.00E-05,1,1,1,1.9
ENSMUSG00000015522,ARNT,aryl hydrocarbon receptor nuclear translocator,nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|cytoplasm|,"response to hypoxia|response to hypoxia|embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|response to toxic substance|positive regulation vascular endothelial growth factor production|cell differentiation|intracellular receptor signaling pathway|positive regulation of protein sumoylation|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hormone biosynthetic process|regulation of RNA biosynthetic process|",transcription factor binding transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription coactivator activity|signal transducer activity|aryl hydrocarbon receptor activity|protein binding|transcription factor binding|aryl hydrocarbon receptor binding|enhancer binding|sequence-specific DNA binding|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|,10,1.5,24.8,10,1.4,36.9,1.5,61,61,0.00016,1,1,1.2,2
ENSMUSG00000034165,CCND3,cyclin D3,cyclin-dependent protein kinase holoenzyme complex|nucleus|cytoplasm|membrane|,regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of protein phosphorylation|protein phosphorylation|cell cycle|signal transduction|positive regulation of cell proliferation|hyaluronan biosynthetic process|T cell proliferation|response to peptide hormone|positive regulation of cyclin-dependent protein serine/threonine kinase activity|cell division|regulation of cell cycle|,cyclin-dependent protein serine/threonine kinase activity|protein binding|protein kinase binding|,10,1.2,22.5,10,1.2,30.4,1.2,52.6,52.6,0.00044,1,1,0.9,1.7
ENSMUSG00000026341,ACTR3,ARP3 actin-related protein 3,Golgi membrane|podosome|cell|cytoplasm|cytoskeleton|actin filament|cell-cell junction|membrane|lamellipodium|lamellipodium|hemidesmosome|cell leading edge|cell projection|excitatory synapse|extracellular vesicular exosome|,establishment or maintenance of cell polarity|asymmetric cell division|positive regulation of lamellipodium assembly|meiotic chromosome movement towards spindle pole|cell projection organization|positive regulation of actin filament polymerization|meiotic cytokinesis|regulation of myosin II filament organization|positive regulation of neuron differentiation|positive regulation of dendrite morphogenesis|meiotic cell cycle|positive regulation of filopodium assembly|spindle localization|cilium morphogenesis|,nucleotide binding|actin binding|protein binding|ATP binding|,9,2.8,24.9,10,3.3,28.9,3.2,52.6,52.6,0.00044,1,1,2.4,5.3
ENSMUSG00000000078,KLF6,Kruppel-like factor 6,nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cytokine-mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,1.1,24.9,10,1.1,23.9,1.1,48.4,48.4,0.00083,1,1,0.8,1.7
ENSMUSG00000023004,TUBA1B,"tubulin, alpha 1B",cytoplasm|cytoskeleton|microtubule|cytoplasmic microtubule|protein complex|extracellular vesicular exosome|,GTP catabolic process|microtubule-based process|protein polymerization|cellular response to interleukin-4|,nucleotide binding|double-stranded RNA binding|GTPase activity|structural constituent of cytoskeleton|protein binding|GTP binding|,3,1.8,12.9,5,2.5,34.6,2.4,46,46,0.00136,0,1,1.5,4.1
ENSMUSG00000017210,MED24,mediator complex subunit 24,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|histone acetylation|stem cell maintenance|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|protein heterooligomerization|",RNA polymerase II transcription cofactor activity|transcription cofactor activity|transcription coactivator activity|histone acetyltransferase activity|receptor activity|thyroid hormone receptor binding|,10,2,5.89,10,-2,44.7,-1.9,46,-46,0.00136,0,1,-3,-1.1
ENSMUSG00000031400,G6PDX,glucose-6-phosphate dehydrogenase X-linked,nucleus|cytoplasm|cytosol|cytoplasmic side of plasma membrane|membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,"cytokine production|cytokine production|angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure|vasodilation by angiotensin involved in regulation of systemic arterial blood pressure|carbohydrate metabolic process|glucose metabolic process|pentose-phosphate shunt|cholesterol biosynthetic process|NADP metabolic process|NADPH regeneration|NADP biosynthetic process|NADP biosynthetic process|glutathione metabolic process|glutathione metabolic process|response to oxidative stress|pentose-phosphate shunt, oxidative branch|negative regulation of protein glutathionylation|pentose biosynthetic process|pentose biosynthetic process|pentose biosynthetic process|interleukin-10 production|interleukin-12 production|cellular response to oxidative stress|regulation of multicellular organism growth|erythrocyte maturation|regulation of neuron apoptotic process|response to ethanol|ribose phosphate biosynthetic process|erythrocyte development|glucose 6-phosphate metabolic process|oxidation-reduction process|oxidation-reduction process|",glucose-6-phosphate dehydrogenase activity|glucose-6-phosphate dehydrogenase activity|glucose-6-phosphate dehydrogenase activity|glucose binding|oxidoreductase activity|carbohydrate binding|protein homodimerization activity|protein homodimerization activity|NADP binding|,9,1.8,26.9,7,2.2,20,2.1,45.8,45.8,0.00141,0,1,1.3,3.1
ENSMUSG00000022148,FYB,FYN binding protein,nucleus|cytoplasm|,None,protein complex binding|,10,1.2,23.7,10,1.1,20.3,1.1,43.5,43.5,0.00196,0,1,0.8,1.6
ENSMUSG00000030400,ERCC2,"excision repair cross-complementing rodent repair deficiency, complementation group 2",core TFIIH complex|nucleus|nucleus|holo TFIIH complex|cytoplasm|spindle|cytoskeleton|cyclin-dependent protein kinase activating kinase holoenzyme complex|MMXD complex|,"in utero embryonic development|nucleobase-containing compound metabolic process|ATP catabolic process|DNA repair|transcription-coupled nucleotide-excision repair|nucleotide-excision repair|nucleotide-excision repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|apoptotic process|cellular response to DNA damage stimulus|response to oxidative stress|response to oxidative stress|chromosome segregation|aging|cell proliferation|response to UV|UV protection|UV protection|post-embryonic development|spinal cord development|hair cycle process|extracellular matrix organization|bone mineralization|central nervous system myelin formation|DNA duplex unwinding|nucleotide-excision repair, DNA incision|multicellular organism growth|hair cell differentiation|hair cell differentiation|embryonic cleavage|erythrocyte maturation|positive regulation of DNA binding|skin development|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|hair follicle maturation|hematopoietic stem cell differentiation|regulation of mitotic cell cycle phase transition|","nucleotide binding|nucleic acid binding|DNA binding|ATP-dependent DNA helicase activity|helicase activity|protein kinase activity|ATP binding|protein C-terminus binding|ATP-dependent helicase activity|DNA-dependent ATPase activity|RNA polymerase II carboxy-terminal domain kinase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|5'-3' DNA helicase activity|metal ion binding|protein N-terminus binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",8,2.5,22.9,7,1.6,22.6,2.2,43.2,43.2,0.00204,0,1,1.3,4
ENSMUSG00000025809,ITGB1,integrin beta 1 (fibronectin receptor beta),acrosomal vesicle|basement membrane|cytoplasm|endosome|plasma membrane|plasma membrane|cell-cell junction|adherens junction|focal adhesion|integrin complex|external side of plasma membrane|cell surface|cell surface|intercalated disc|membrane|integral component of membrane|cell junction|hemidesmosome|filopodium|neuromuscular junction|neuromuscular junction|ruffle membrane|integrin alpha3-beta1 complex|integrin alpha7-beta1 complex|integrin alpha7-beta1 complex|integrin alpha9-beta1 complex|myelin sheath abaxonal region|sarcolemma|sarcolemma|cell projection|receptor complex|membrane raft|synapse|extracellular vesicular exosome|,G1/S transition of mitotic cell cycle|in utero embryonic development|cell fate specification|tissue homeostasis|cell migration involved in sprouting angiogenesis|cellular calcium ion homeostasis|cell adhesion|leukocyte cell-cell adhesion|cell-matrix adhesion|cell-matrix adhesion|cell-matrix adhesion|calcium-independent cell-matrix adhesion|integrin-mediated signaling pathway|multicellular organismal development|regulation of G-protein coupled receptor protein signaling pathway|positive regulation of cell proliferation|negative regulation of cell proliferation|germ cell migration|positive regulation of cell-substrate adhesion|positive regulation of neuron projection development|cell migration|formation of radial glial scaffolds|positive regulation of cell migration|neuron projection development|negative regulation of cell projection organization|cell-substrate adhesion|protein transport within lipid bilayer|positive regulation of apoptotic process|positive regulation of MAPK cascade|sarcomere organization|negative regulation of cell differentiation|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of endocytosis|axon extension|axon extension|cardiac muscle tissue development|positive regulation of peptidyl-tyrosine phosphorylation|regulation of cell cycle|cardiac muscle cell differentiation|tight junction assembly|negative regulation of anoikis|,glycoprotein binding|fibronectin binding|protease binding|actin binding|receptor activity|receptor binding|integrin binding|integrin binding|protein binding|collagen binding|kinase binding|protein kinase binding|protein domain specific binding|protein complex binding|peptide binding|laminin binding|laminin binding|metal ion binding|protein heterodimerization activity|cell adhesion molecule binding|alpha-actinin binding|,10,3.5,21.1,10,3.2,21.2,3.5,41.6,41.6,0.00248,0,0,3,5.9
ENSMUSG00000028156,EIF4E,eukaryotic translation initiation factor 4E,cytoplasmic mRNA processing body|cytoplasm|cytoplasm|mRNA cap binding complex|mRNA cap binding complex|cytoplasmic stress granule|eukaryotic translation initiation factor 4F complex|RISC complex|chromatoid body|protein complex|extracellular vesicular exosome|,G1/S transition of mitotic cell cycle|translation|translational initiation|regulation of translation|positive regulation of mitotic cell cycle|,RNA binding|translation initiation factor activity|translation initiation factor activity|protein binding|eukaryotic initiation factor 4G binding|poly(A) RNA binding|,8,0.7,12.3,7,1.3,30.4,1,40.7,40.7,0.00266,0,0,0.7,1.7
ENSMUSG00000028224,NBN,nibrin,"chromosome, telomeric region|nuclear chromosome, telomeric region|intracellular|nucleus|nucleus|replication fork|chromosome|nucleolus|PML body|Mre11 complex|site of double-strand break|nuclear inclusion body|",DNA damage checkpoint|telomere maintenance|in utero embryonic development|blastocyst growth|DNA repair|double-strand break repair|cellular response to DNA damage stimulus|cell cycle|mitotic cell cycle checkpoint|mitotic G2 DNA damage checkpoint|mitotic G2 DNA damage checkpoint|meiotic nuclear division|cell proliferation|positive regulation of cell proliferation|positive regulation of protein autophosphorylation|DNA duplex unwinding|positive regulation of kinase activity|isotype switching|negative regulation of neuron differentiation|regulation of fibroblast proliferation|neuromuscular process controlling balance|intrinsic apoptotic signaling pathway|,damaged DNA binding|ATP-dependent DNA helicase activity|transcription factor binding|protein N-terminus binding|,10,0.7,5.28,10,1.6,38.4,1.4,40.4,40.4,0.00273,0,0,0.8,2
ENSMUSG00000079111,KDELR2,KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2,endoplasmic reticulum|cis-Golgi network|membrane|integral component of membrane|extracellular vesicular exosome|,protein retention in ER lumen|transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|ER retention sequence binding|,10,1.7,23.7,10,0.8,18.9,1.2,39,39,0.00307,0,0,0.7,1.9
ENSMUSG00000030265,KRAS,v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,intracellular|mitochondrion|plasma membrane|membrane|membrane|membrane|membrane raft|,"positive regulation of protein phosphorylation|GTP catabolic process|signal transduction|small GTPase mediated signal transduction|Ras protein signal transduction|Ras protein signal transduction|positive regulation of cell proliferation|visual learning|positive regulation of gene expression|cytokine-mediated signaling pathway|actin cytoskeleton organization|regulation of synaptic transmission, GABAergic|positive regulation of Rac protein signal transduction|positive regulation of MAP kinase activity|negative regulation of neuron apoptotic process|negative regulation of cell differentiation|regulation of long-term neuronal synaptic plasticity|positive regulation of nitric-oxide synthase activity|positive regulation of NF-kappaB transcription factor activity|striated muscle cell differentiation|epithelial tube branching involved in lung morphogenesis|epithelial tube branching involved in lung morphogenesis|",nucleotide binding|GTPase activity|GTPase activity|protein binding|GTP binding|GMP binding|GDP binding|LRR domain binding|protein complex binding|,6,1.9,37.6,6,-1.7,10.9,1.9,38.3,38.3,0.00323,0,0,1.1,3.3
ENSMUSG00000024212,MLLT1,"myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1",nucleus|nucleus|cytoplasm|,negative regulation of protein kinase activity|,protein binding|,10,-0.7,18.9,10,-0.7,19.7,-0.7,38.2,-38.2,0.00328,0,0,-1,-0.5
ENSMUSG00000041147,BRCA2,breast cancer 2,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|centrosome|centrosome|cytoskeleton|secretory granule|BRCA2-MAGE-D1 complex|protein complex|,"double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|cytokinesis|oocyte maturation|inner cell mass cell proliferation|DNA repair|nucleotide-excision repair|double-strand break repair|double-strand break repair|DNA recombination|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cell cycle|male meiosis I|spermatogenesis|spermatogenesis|brain development|cell aging|cell proliferation|female gonad development|intrinsic apoptotic signaling pathway in response to DNA damage|response to X-ray|response to UV-C|response to gamma radiation|hemopoiesis|mammary gland development|homologous chromosome orientation involved in meiotic metaphase I plate congression|regulation of cytokinesis|negative regulation of mammary gland epithelial cell proliferation|multicellular organism growth|regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|chordate embryonic development|histone H3 acetylation|histone H4 acetylation|positive regulation of transcription, DNA-templated|positive regulation of mitotic cell cycle|replication fork protection|chromosome organization|centrosome duplication|centrosome duplication|",protease binding|DNA binding|single-stranded DNA binding|single-stranded DNA binding|protein binding|H3 histone acetyltransferase activity|H4 histone acetyltransferase activity|gamma-tubulin binding|gamma-tubulin binding|,9,2.3,32.8,10,0.7,12.5,0.8,38,38,0.00333,0,0,0.6,2.9
ENSMUSG00000002496,TSC2,tuberous sclerosis 2,intracellular|cell|cytoplasm|cytoplasm|cytoplasm|cytosol|cytoskeleton|caveola|membrane|dendrite|growth cone|TSC1-TSC2 complex|TSC1-TSC2 complex|neuron projection|neuronal cell body|intracellular membrane-bounded organelle|protein complex|membrane raft|perinuclear region of cytoplasm|,response to hypoxia|neural tube closure|negative regulation of protein kinase activity|protein import into nucleus|acute-phase response|signal transduction|heart development|protein localization|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|phosphatidylinositol 3-kinase signaling|negative regulation of phosphatidylinositol 3-kinase signaling|cell projection organization|regulation of endocytosis|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of TOR signaling|negative regulation of TOR signaling|positive regulation of Ras GTPase activity|negative regulation of MAP kinase activity|protein kinase B signaling|protein kinase B signaling|positive regulation of GTPase activity|establishment of protein localization|negative regulation of cell size|regulation of insulin receptor signaling pathway|negative regulation of insulin receptor signaling pathway|insulin-like growth factor receptor signaling pathway|insulin-like growth factor receptor signaling pathway|negative regulation of epithelial cell proliferation|positive chemotaxis|regulation of small GTPase mediated signal transduction|protein homooligomerization|protein heterooligomerization|regulation of cell cycle|regulation of cell cycle|negative regulation of protein kinase B signaling|negative regulation of protein kinase B signaling|,GTPase activator activity|GTPase activator activity|protein binding|phosphatase binding|protein homodimerization activity|protein heterodimerization activity|14-3-3 protein binding|,9,1.7,19.1,9,1.5,19.9,1.6,37.9,37.9,0.00336,0,0,1.1,2.5
ENSMUSG00000022663,ATG3,autophagy related 3,cytoplasmic ubiquitin ligase complex|cytoplasmic ubiquitin ligase complex|cytoplasm|cytosol|cytosol|,autophagic vacuole assembly|mitochondrion degradation|cellular protein modification process|transport|autophagy|protein transport|protein ubiquitination|mitochondrial fragmentation involved in apoptotic process|nucleophagy|regulation of cilium assembly|,"protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|Atg8 ligase activity|Atg12 ligase activity|small conjugating protein ligase activity|enzyme binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-1.1,23.2,10,-0.9,14.6,-1.1,37.2,-37.2,0.00349,0,0,-1.5,-0.8
ENSMUSG00000036980,TAF6,"TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|cytoplasm|transcription factor TFTC complex|MLL1 complex|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|negative regulation of cell proliferation|negative regulation of cell cycle|regulation of sequence-specific DNA binding transcription factor activity|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein heterodimerization activity|,5,1.2,13.2,7,4.9,30.5,4.9,37,37,0.00356,0,0,3.8,8.2
ENSMUSG00000024513,MBD2,methyl-CpG binding domain protein 2,histone deacetylase complex|chromatin|nuclear chromatin|heterochromatin|nucleus|nucleus|cytoplasm|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of Wnt signaling pathway|regulation of cell proliferation|maternal behavior|ATP-dependent chromatin remodeling|cellular protein complex assembly|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|DNA binding|chromatin binding|mRNA binding|methyl-CpG binding|methyl-CpG binding|protein domain specific binding|nucleosomal DNA binding|siRNA binding|C2H2 zinc finger domain binding|,10,-1.1,27.4,10,-0.6,13.5,-1,36.9,-36.9,0.00358,0,0,-1.3,-0.6
ENSMUSG00000041459,TARDBP,TAR DNA binding protein,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|mRNA processing|RNA splicing|negative regulation by host of viral transcription|positive regulation of transcription from RNA polymerase II promoter|3'-UTR-mediated mRNA stabilization|",nucleotide binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|double-stranded DNA binding|RNA binding|mRNA 3'-UTR binding|protein binding|identical protein binding|poly(A) RNA binding|,7,-1.9,26.4,6,-1.3,11.6,-1.8,36.4,-36.4,0.00378,0,0,-3.2,-1
ENSMUSG00000031807,PGLS,6-phosphogluconolactonase,cytoplasm|extracellular vesicular exosome|,"carbohydrate metabolic process|pentose-phosphate shunt|pentose-phosphate shunt, oxidative branch|",hydrolase activity|6-phosphogluconolactonase activity|monosaccharide binding|,10,1.1,20.5,10,0.8,15,1,33.4,33.4,0.00498,0,0,0.6,1.5
ENSMUSG00000006585,CDT1,chromatin licensing and DNA replication factor 1,nucleus|nucleus|,DNA replication checkpoint|DNA replication checkpoint|DNA replication|cell cycle|regulation of DNA-dependent DNA replication initiation|regulation of DNA-dependent DNA replication initiation|regulation of nuclear cell cycle DNA replication|,DNA binding|protein binding|,10,2.5,26.4,9,1.4,9.18,2.1,33.1,33.1,0.00519,0,0,1.1,4.1
ENSMUSG00000031659,ADCY7,adenylate cyclase 7,plasma membrane|membrane|integral component of membrane|,cAMP biosynthetic process|cAMP biosynthetic process|cAMP biosynthetic process|activation of adenylate cyclase activity|cyclic nucleotide biosynthetic process|positive regulation of cAMP biosynthetic process|intracellular signal transduction|cellular response to ethanol|,nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|adenylate cyclase activity|ATP binding|lyase activity|phosphorus-oxygen lyase activity|metal ion binding|,10,0.8,19.7,10,0.7,13.7,0.8,33,33,0.00523,0,0,0.5,1.2
ENSMUSG00000001847,RAC1,RAS-related C3 botulinum substrate 1,Golgi membrane|phagocytic cup|intracellular|cytoplasm|cytoplasm|trans-Golgi network|cytosol|plasma membrane|membrane|membrane|cytoplasmic membrane-bounded vesicle|extrinsic component of plasma membrane|lamellipodium|cytoplasmic vesicle|ruffle membrane|cytoplasmic ribonucleoprotein granule|cell projection|extracellular vesicular exosome|,"positive regulation of protein phosphorylation|auditory receptor cell morphogenesis|mast cell chemotaxis|epithelial cell morphogenesis|GTP catabolic process|GTP catabolic process|endocytosis|phagocytosis, engulfment|cellular component movement|chemotaxis|hyperosmotic response|cytoskeleton organization|actin filament organization|cell adhesion|G-protein coupled receptor signaling pathway|small GTPase mediated signal transduction|axon guidance|cell proliferation|positive regulation of lamellipodium assembly|dendrite development|cell migration|cerebral cortex radially oriented cell migration|embryonic olfactory bulb interneuron precursor migration|lamellipodium assembly|lamellipodium assembly|lamellipodium assembly|actin cytoskeleton organization|actin filament polymerization|regulation of cell migration|regulation of cell migration|positive regulation of actin filament polymerization|ruffle organization|negative regulation of interleukin-23 production|substrate adhesion-dependent cell spreading|positive regulation of phosphatidylinositol 3-kinase activity|engulfment of apoptotic cell|cell-cell junction organization|bone resorption|positive regulation of DNA replication|anatomical structure arrangement|dendrite morphogenesis|cell motility|localization within membrane|Wnt signaling pathway, planar cell polarity pathway|regulation of respiratory burst|semaphorin-plexin signaling pathway|dopaminergic neuron differentiation|protein localization to plasma membrane|cochlea morphogenesis|ruffle assembly|",nucleotide binding|GTPase activity|GTPase activity|protein binding|GTP binding|GTP binding|Rab GTPase binding|enzyme binding|protein kinase binding|GTP-dependent protein binding|thioesterase binding|,10,0.9,17.6,10,1.1,15.8,1,32.6,32.6,0.00543,0,0,0.7,1.5
ENSMUSG00000018841,RAD51D,RAD51 homolog D,"chromosome, telomeric region|nucleus|replication fork|chromosome|centrosome|Rad51B-Rad51C-Rad51D-XRCC2 complex|",telomere maintenance|double-strand break repair via homologous recombination|ATP catabolic process|DNA metabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|strand invasion|,nucleotide binding|four-way junction DNA binding|DNA binding|single-stranded DNA binding|ATP binding|DNA-dependent ATPase activity|gamma-tubulin binding|,7,1.8,32.4,6,0.8,1.18,1.8,31.5,31.5,0.00637,0,0,1,3.3
ENSMUSG00000029414,KNTC1,kinetochore associated 1,"chromosome, centromeric region|kinetochore|spindle pole|nucleus|chromosome|cytoplasm|kinetochore microtubule|cytoskeleton|plasma membrane|actin cytoskeleton|",cell cycle|mitotic nuclear division|mitotic cell cycle checkpoint|cell division|,molecular_function|,8,1.1,6.71,8,2.6,27.7,2.5,31.2,31.2,0.00663,0,0,1.1,4.7
ENSMUSG00000026639,LAMB3,"laminin, beta 3",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basement membrane|laminin-5 complex|,cell adhesion|brown fat cell differentiation|,protein complex binding|,9,2.3,23.7,9,1.7,8.2,2.1,30.9,30.9,0.00692,0,0,1.5,3.9
ENSMUSG00000023505,CDCA3,cell division cycle associated 3,cellular_component|cytoplasm|,cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,10,1.2,18.7,10,1.6,13,1.2,30.9,30.9,0.00692,0,0,0.8,2.1
ENSMUSG00000017428,PSMD11,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 11",proteasome complex|nucleus|proteasome regulatory particle|membrane|proteasome accessory complex|proteasome accessory complex|extracellular vesicular exosome|,ubiquitin-dependent protein catabolic process|proteasome assembly|stem cell differentiation|,protein binding|,6,0.9,12.6,6,1.5,19.5,1.2,30.7,30.7,0.00713,0,0,0.8,2.2
ENSMUSG00000022570,TSTA3,tissue specific transplantation antigen P35B,extracellular vesicular exosome|,metabolic process|GDP-mannose metabolic process|cytolysis|'de novo' GDP-L-fucose biosynthetic process|oxidation-reduction process|,catalytic activity|oxidoreductase activity|isomerase activity|GDP-L-fucose synthase activity|coenzyme binding|,10,0.6,12.6,10,1.1,19.8,0.9,30.4,30.4,0.00746,0,0,0.6,1.4
ENSMUSG00000039509,NUP133,nucleoporin 133,"chromosome, centromeric region|kinetochore|condensed chromosome kinetochore|condensed chromosome outer kinetochore|nucleus|nuclear pore|nuclear pore|chromosome|membrane|nuclear pore outer ring|",mRNA export from nucleus|mRNA export from nucleus|transport|nuclear pore organization|protein transport|paraxial mesoderm development|mRNA transport|,nucleocytoplasmic transporter activity|nucleocytoplasmic transporter activity|,10,2.3,28,10,0.9,6.73,0.9,30.4,30.4,0.00746,0,0,0.7,3.8
ENSMUSG00000025261,HUWE1,"HECT, UBA and WWE domain containing 1",nucleus|nucleus|cytoplasm|cytoplasm|membrane|extracellular vesicular exosome|,protein polyubiquitination|DNA repair|base-excision repair|protein monoubiquitination|cellular response to DNA damage stimulus|histone ubiquitination|cell differentiation|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"DNA binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1.5,11.7,10,1,18.7,1.5,29.8,29.8,0.00802,0,0,0.8,2.1
ENSMUSG00000019969,PSEN1,presenilin 1,kinetochore|intracellular|intracellular|cell|nucleus|nuclear outer membrane|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|lysosomal membrane|lysosomal membrane|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|smooth endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|Golgi apparatus|centrosome|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cell cortex|cell surface|cell surface|membrane|integral component of membrane|apical plasma membrane|Z disc|axon|dendrite|growth cone|cytoplasmic vesicle|neuromuscular junction|neuromuscular junction|nuclear membrane|ciliary rootlet|neuron projection|neuronal cell body|dendritic shaft|membrane-bounded organelle|protein complex|membrane raft|membrane raft|perinuclear region of cytoplasm|gamma-secretase complex|,"autophagic vacuole assembly|negative regulation of transcription from RNA polymerase II promoter|activation of MAPKK activity|blood vessel development|cell fate specification|somitogenesis|somitogenesis|neuron migration|positive regulation of receptor recycling|negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|heart looping|hematopoietic progenitor cell differentiation|T cell activation involved in immune response|myeloid leukocyte differentiation|negative regulation of protein kinase activity|protein glycosylation|proteolysis|membrane protein ectodomain proteolysis|membrane protein ectodomain proteolysis|calcium ion transport|mitochondrial transport|cellular calcium ion homeostasis|autophagy|apoptotic process|cellular response to DNA damage stimulus|response to oxidative stress|response to oxidative stress|cell adhesion|negative regulation of epidermal growth factor-activated receptor activity|regulation of epidermal growth factor-activated receptor activity|Notch signaling pathway|Notch signaling pathway|Notch receptor processing|brain development|heart development|learning or memory|memory|memory|embryo development|embryo development|post-embryonic development|protein transport|L-glutamate transport|choline transport|synaptic vesicle targeting|single organismal cell-cell adhesion|protein processing|protein processing|cerebral cortex cell migration|Cajal-Retzius cell differentiation|dorsal/ventral neural tube patterning|cerebral cortex development|neurogenesis|neuron differentiation|embryonic limb morphogenesis|forebrain development|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|endoplasmic reticulum calcium ion homeostasis|endoplasmic reticulum calcium ion homeostasis|endoplasmic reticulum calcium ion homeostasis|beta-amyloid formation|segmentation|intracellular signal transduction|locomotion|regulation of phosphorylation|anagen|amyloid precursor protein catabolic process|myeloid dendritic cell differentiation|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of catalytic activity|regulation of protein binding|positive regulation of MAP kinase activity|negative regulation of neuron apoptotic process|skin morphogenesis|cellular protein metabolic process|cellular protein metabolic process|cellular protein metabolic process|positive regulation of protein kinase activity|regulation of synaptic plasticity|regulation of synaptic plasticity|thymus development|thymus development|neuron development|skeletal system morphogenesis|brain morphogenesis|beta-amyloid metabolic process|epithelial cell proliferation|negative regulation of axonogenesis|positive regulation of coagulation|T cell receptor signaling pathway|neuron apoptotic process|negative regulation of ubiquitin-protein transferase activity|smooth endoplasmic reticulum calcium ion homeostasis|protein maturation|regulation of synaptic transmission, glutamatergic|canonical Wnt signaling pathway|regulation of resting membrane potential|calcium ion transmembrane transport|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of apoptotic signaling pathway|","endopeptidase activity|endopeptidase activity|endopeptidase activity|aspartic-type endopeptidase activity|calcium channel activity|protein binding|beta-catenin binding|beta-catenin binding|peptidase activity|hydrolase activity|PDZ domain binding|aspartic endopeptidase activity, intramembrane cleaving|cadherin binding|",10,0.7,7.04,10,1.1,24.1,1,29.6,29.6,0.00823,0,0,0.7,1.8
ENSMUSG00000024906,MUS81,MUS81 endonuclease homolog (yeast),nucleus|intercellular bridge|,"DNA catabolic process, endonucleolytic|DNA metabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|response to intra-S DNA damage checkpoint signaling|",DNA binding|nuclease activity|endonuclease activity|hydrolase activity|metal ion binding|3'-flap endonuclease activity|,10,1.2,17.2,10,0.9,13,1.1,29.4,29.4,0.00851,0,0,0.7,1.7
ENSMUSG00000039910,CITED2,"Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2",nuclear chromatin|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|blood vessel development|vasculogenesis|response to hypoxia|response to hypoxia|in utero embryonic development|trophectodermal cell differentiation|neural tube formation|neural tube closure|liver development|embryonic placenta development|vasculature development|vasculature development|heart looping|lens morphogenesis in camera-type eye|hematopoietic progenitor cell differentiation|leukocyte differentiation|outflow tract morphogenesis|regulation of organ formation|endocardial cushion development|ventricular septum development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transforming growth factor beta receptor signaling pathway|multicellular organismal development|determination of left/right symmetry|central nervous system development|peripheral nervous system development|heart development|heart development|heart development|sex determination|cell proliferation|male gonad development|positive regulation of gene expression|negative regulation of gene expression|cranial nerve morphogenesis|positive regulation of cell-cell adhesion|cell differentiation|adrenal gland development|negative regulation of cell migration|positive regulation of transforming growth factor beta receptor signaling pathway|granulocyte differentiation|response to fluid shear stress|positive regulation of peroxisome proliferator activated receptor signaling pathway|adrenal cortex formation|skeletal muscle cell differentiation|negative regulation of apoptotic process|response to estrogen|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|decidualization|spleen development|thymus development|thymus development|embryonic camera-type eye morphogenesis|erythrocyte development|embryonic process involved in female pregnancy|bone morphogenesis|cardiac septum morphogenesis|ventricular septum morphogenesis|embryonic heart tube left/right pattern formation|pulmonary artery morphogenesis|cardiac neural crest cell development involved in heart development|determination of heart left/right asymmetry|negative regulation of transcription from RNA polymerase II promoter in response to hypoxia|left/right axis specification|nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of male gonad development|regulation of RNA biosynthetic process|",RNA polymerase II activating transcription factor binding|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription corepressor activity|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription cofactor activity|transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|transcription corepressor activity|protein binding|histone acetyltransferase binding|SMAD binding|LBD domain binding|,10,-0.7,12.9,10,-1.3,18.9,-1,29.2,-29.2,0.0087,0,0,-1.6,-0.6
ENSMUSG00000039361,PICALM,phosphatidylinositol binding clathrin assembly protein,intracellular|nucleus|endosome|Golgi apparatus|plasma membrane|coated pit|coated pit|synaptic vesicle|membrane|membrane|clathrin coat|AP-2 adaptor complex|clathrin coat of coated pit|clathrin-coated vesicle|cytoplasmic vesicle|presynaptic membrane|neuronal cell body|intracellular membrane-bounded organelle|synapse|postsynaptic membrane|perinuclear region of cytoplasm|neurofibrillary tangle|neuronal postsynaptic density|,"endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|multicellular organismal development|axonogenesis|axonogenesis|cell proliferation|negative regulation of gene expression|vesicle-mediated transport|endosomal transport|hemopoiesis|regulation of endocytosis|receptor internalization|regulation of protein localization|cargo loading into vesicle|positive regulation of transcription, DNA-templated|negative regulation of receptor-mediated endocytosis|clathrin coat assembly|dendrite morphogenesis|dendrite morphogenesis|regulation of protein transport|iron ion homeostasis|clathrin-mediated endocytosis|iron ion import into cell|positive regulation of neuron death|positive regulation of beta-amyloid formation|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|",phospholipid binding|1-phosphatidylinositol binding|SH3 domain binding|clathrin binding|clathrin heavy chain binding|clathrin adaptor activity|identical protein binding|,10,1,9.03,10,1.1,19.4,1,27.8,27.8,0.0108,0,0,0.8,2
ENSMUSG00000070847,VMN2R30,"vomeronasal 2, receptor 30",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,7,2.5,26.2,7,1.1,3.61,2.2,27.3,27.3,0.0114,0,0,1.2,4
ENSMUSG00000058355,ABCE1,"ATP-binding cassette, sub-family E (OABP), member 1",cytoplasm|mitochondrion|membrane|,None,nucleotide binding|ATP binding|ATPase activity|iron-sulfur cluster binding|,7,3.2,29.4,5,0,0,3.2,27.2,27.2,0.0116,0,0,2.4,5.9
ENSMUSG00000049728,ZFP668,zinc finger protein 668,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-1,7.31,10,-0.8,20.4,-0.9,27.2,-27.2,0.0116,0,0,-1.4,-0.6
ENSMUSG00000062078,QK,quaking,nucleus|cytoplasm|,vasculogenesis|mRNA processing|regulation of translation|transport|multicellular organismal development|spermatid development|axon ensheathment|RNA splicing|positive regulation of gene expression|cell differentiation|myelination|muscle cell differentiation|long-chain fatty acid biosynthetic process|mRNA transport|3'-UTR-mediated mRNA destabilization|,RNA binding|mRNA binding|SH3 domain binding|poly(A) RNA binding|,10,1.1,13.8,10,1.8,14.1,1.2,26.7,26.7,0.0126,0,0,0.8,2.2
ENSMUSG00000025979,MOB4,"MOB family member 4, phocein",cytoplasm|Golgi apparatus|cytosol|membrane|neuronal cell body|dendritic spine|perinuclear region of cytoplasm|,transport|,kinase binding|metal ion binding|,8,1.1,15.1,8,0.9,12.7,1,26.7,26.7,0.0126,0,0,0.6,1.5
ENSMUSG00000020235,FZR1,fizzy/cell division cycle 20 related 1 (Drosophila),nucleus|anaphase-promoting complex|nuclear membrane|,DNA repair|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|positive regulation of cell proliferation|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|G2 DNA damage checkpoint|regulation of meiosis|positive regulation of protein catabolic process|cell division|activation of anaphase-promoting complex activity|lens fiber cell differentiation|negative regulation of cell aging|,protein binding|,9,1.3,7.73,8,2.9,22.6,2.8,26.7,26.7,0.0126,0,0,1.8,4.8
ENSMUSG00000022702,HIRA,histone cell cycle regulation defective homolog A (S. cerevisiae),nuclear chromatin|nuclear chromatin|nucleus|protein complex|,"osteoblast differentiation|DNA replication-independent nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|gastrulation|chromatin modification|muscle cell differentiation|",chromatin binding|protein binding|,9,-0.5,15.1,10,-0.8,12.8,-0.6,26.6,-26.6,0.0128,0,0,-1.1,-0.4
ENSMUSG00000041849,CARD6,"caspase recruitment domain family, member 6",cytoplasm|,regulation of I-kappaB kinase/NF-kappaB signaling|,molecular_function|,10,0.9,11.2,10,2.8,22.2,0.8,26.5,26.5,0.0131,0,0,0.6,4.2
ENSMUSG00000016087,FLI1,Friend leukemia integration 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|blood circulation|organ morphogenesis|cellular process|megakaryocyte development|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,8,-1.7,20.2,9,-0.9,9.14,-0.9,26.1,-26.1,0.0138,0,0,-2.2,-0.5
ENSMUSG00000034116,VAV1,vav 1 oncogene,intracellular|cell-cell junction|,phagocytosis|immune response|G-protein coupled receptor signaling pathway|integrin-mediated signaling pathway|small GTPase mediated signal transduction|T cell differentiation|T cell differentiation|neutrophil chemotaxis|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|T cell activation|regulation of GTPase activity|positive regulation of GTPase activity|positive regulation of cell adhesion|reactive oxygen species metabolic process|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|Rac guanyl-nucleotide exchange factor activity|metal ion binding|,10,0.8,18.2,10,0.7,8.28,0.8,26,26,0.0141,0,0,0.5,1.2
ENSMUSG00000041133,SMC1A,structural maintenance of chromosomes 1A,"chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|meiotic cohesin complex|meiotic cohesin complex|",DNA repair|cellular response to DNA damage stimulus|cell cycle|sister chromatid cohesion|mitotic nuclear division|mitotic cell cycle checkpoint|meiotic nuclear division|meiotic nuclear division|stem cell maintenance|negative regulation of DNA endoreduplication|signal transduction in response to DNA damage|chromosome organization|cell division|,nucleotide binding|chromatin binding|chromatin binding|protein binding|ATP binding|mediator complex binding|poly(A) RNA binding|protein heterodimerization activity|,6,1.6,17.4,6,2.1,9.56,2,25.9,25.9,0.0144,0,0,1.1,3.1
ENSMUSG00000035783,ACTA2,"actin, alpha 2, smooth muscle, aorta",extracellular space|cytoplasm|cytoplasm|cytoskeleton|actin cytoskeleton|actin cytoskeleton|smooth muscle contractile fiber|,muscle contraction|regulation of blood pressure|vascular smooth muscle contraction|,nucleotide binding|protein binding|ATP binding|,10,1.5,15.9,10,1.5,10.1,1.5,25.6,25.6,0.0151,0,0,0.9,2.4
ENSMUSG00000018921,PELP1,"proline, glutamic acid and leucine rich protein 1",nucleus|nucleolus|cytoplasm|membrane|MLL1 complex|,"transcription, DNA-templated|biological_process|",poly(A) RNA binding|,8,1.1,7.12,8,1.6,19.4,1.1,25.4,25.4,0.0156,0,0,0.8,2.4
ENSMUSG00000038252,NCAPD2,"non-SMC condensin I complex, subunit D2",nuclear chromosome|condensed chromosome|condensed chromosome|condensin complex|nucleus|chromosome|cytoplasm|cytoplasm|membrane|pronucleus|,cell cycle|mitotic nuclear division|mitotic chromosome condensation|chromosome condensation|cell division|,histone binding|,10,-1.1,10.3,9,1.6,19.6,1.3,25.2,25.2,0.0161,0,0,0.8,2.3
ENSMUSG00000048960,PREX2,"phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2",cellular_component|,G-protein coupled receptor signaling pathway|adult locomotory behavior|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|dendrite morphogenesis|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rac GTPase activator activity|Rac guanyl-nucleotide exchange factor activity|,10,2.6,21.9,10,1.8,4.7,2.3,25.1,25.1,0.0164,0,0,1.7,4.8
ENSMUSG00000047777,PHF13,PHD finger protein 13,nucleus|,mitotic cell cycle|cell cycle|chromosome segregation|mitotic nuclear division|mitotic chromosome condensation|chromatin modification|chromosome condensation|cell division|,chromatin binding|zinc ion binding|metal ion binding|,10,2.1,24.7,10,0.5,3.3,0.6,25.1,25.1,0.0164,0,0,0.4,3.5
ENSMUSG00000021939,CTSB,cathepsin B,extracellular region|extracellular space|nucleolus|cytoplasm|mitochondrion|mitochondrion|lysosome|lysosome|caveola|external side of plasma membrane|cell surface|apical plasma membrane|sarcolemma|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|perinuclear region of cytoplasm|extracellular vesicular exosome|,proteolysis|collagen catabolic process|decidualization|regulation of catalytic activity|proteolysis involved in cellular protein catabolic process|negative regulation of cell death|,endopeptidase activity|cysteine-type endopeptidase activity|collagen binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|kininogen binding|protein complex binding|peptide binding|proteoglycan binding|protein self-association|,10,0.9,11.5,10,0.9,14,0.9,25.1,25.1,0.0164,0,0,0.5,1.3
ENSMUSG00000026005,RPE,ribulose-5-phosphate-3-epimerase,intracellular membrane-bounded organelle|,"carbohydrate metabolic process|pentose-phosphate shunt|metabolic process|pentose-phosphate shunt, non-oxidative branch|","catalytic activity|ribulose-phosphate 3-epimerase activity|isomerase activity|racemase and epimerase activity, acting on carbohydrates and derivatives|carbohydrate binding|identical protein binding|protein homodimerization activity|metal ion binding|monosaccharide binding|",8,1.1,19.3,7,1.5,6.98,1.2,25,25,0.0167,0,0,0.7,2.2
ENSMUSG00000026628,ATF3,activating transcription factor 3,nucleus|nucleus|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|gluconeogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|skeletal muscle cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|identical protein binding|sequence-specific DNA binding|,10,1.4,15.5,10,2.2,11.3,1.6,24.8,24.8,0.0174,0,0,1.1,3
ENSMUSG00000064145,ARIH2,ariadne homolog 2 (Drosophila),nucleus|cytoplasm|,protein polyubiquitination|ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|developmental cell growth|protein K63-linked ubiquitination|protein K48-linked ubiquitination|hematopoietic stem cell proliferation|,"nucleic acid binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,2.5,27.8,10,0.2,0.778,2.5,24.6,24.6,0.0181,0,0,1,5
ENSMUSG00000023170,GPS2,G protein pathway suppressor 2,nucleus|transcriptional repressor complex|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of JNK cascade|,transcription corepressor activity|protein binding|,10,0.8,0.164,10,2.5,26.3,2.5,24.3,24.3,0.019,0,0,1.2,5
ENSMUSG00000060843,CTNNA3,"catenin (cadherin associated protein), alpha 3",cytoplasm|cytoskeleton|fascia adherens|fascia adherens|actin cytoskeleton|lamellipodium|,cell adhesion|single organismal cell-cell adhesion|single organismal cell-cell adhesion|,structural molecule activity|protein binding|cadherin binding|,9,2.6,22.4,9,1.1,5.2,2.3,24.2,24.2,0.0194,0,0,1.3,5
ENSMUSG00000078922,TGTP1,T cell specific GTPase 1,cellular_component|,GTP catabolic process|response to interferon-gamma|response to interferon-alpha|cellular response to interferon-beta|,GTPase activity|GTP binding|,9,2.9,22.1,9,1.3,4.95,2.6,23.4,23.4,0.0227,0,0,1.8,5
ENSMUSG00000018707,DYNC1H1,dynein cytoplasmic 1 heavy chain 1,cytoplasm|centrosome|cytoskeleton|axonemal dynein complex|microtubule|membrane|filopodium|dynein complex|extracellular vesicular exosome|,cilium movement|transport|microtubule-based movement|cytoplasmic mRNA processing body assembly|stress granule assembly|,nucleotide binding|motor activity|microtubule motor activity|protein binding|ATP binding|ATPase activity|poly(A) RNA binding|dynein light intermediate chain binding|,10,2.5,26.2,10,0.3,1.77,2.5,23.1,23.1,0.0239,0,0,1,5
ENSMUSG00000068039,TCP1,t-complex protein 1,pericentriolar material|heterochromatin|acrosomal vesicle|zona pellucida receptor complex|nuclear heterochromatin|cytoplasm|Golgi apparatus|centrosome|microtubule organizing center|chaperonin-containing T-complex|cytoskeleton|microtubule|cell body|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|,nucleotide binding|protein binding|ATP binding|poly(A) RNA binding|unfolded protein binding|,8,1.1,9.79,9,1.8,14.2,1.2,22.8,22.8,0.0252,0,0,0.8,2.4
ENSMUSG00000004535,TAX1BP1,Tax1 (human T cell leukemia virus type I) binding protein 1,None,apoptotic process|negative regulation of NF-kappaB transcription factor activity|negative regulation of apoptotic process|,protein binding|kinase binding|ubiquitin binding|,9,1,13.7,9,1.4,10.5,1.2,22.8,22.8,0.0252,0,0,0.7,2
ENSMUSG00000029554,MAD1L1,MAD1 mitotic arrest deficient 1-like 1,"chromosome, centromeric region|kinetochore|kinetochore|kinetochore|nucleus|nuclear pore|chromosome|cytoplasm|cytoskeleton|actin cytoskeleton|mitotic spindle|",cell cycle|mitotic nuclear division|mitotic spindle assembly checkpoint|cell division|regulation of metaphase plate congression|,None,8,2.3,23,8,0.6,3.13,2,22.8,22.8,0.0252,0,0,0.5,4
ENSMUSG00000022881,RFC4,replication factor C (activator 1) 4,nucleus|DNA replication factor C complex|,DNA replication|,nucleotide binding|DNA binding|ATP binding|,5,2.4,24.5,5,-0.4,1.27,2.4,22.6,22.6,0.0261,0,0,1.5,4
ENSMUSG00000032905,ATG12,autophagy related 12,cytoplasm|membrane|pre-autophagosomal structure membrane|Atg12-Atg5-Atg16 complex|protein complex|,autophagic vacuole assembly|mitochondrion degradation|immune system process|C-terminal protein lipidation|autophagy|autophagy|cellular response to nitrogen starvation|nucleophagy|innate immune response|,protein binding|Atg8 ligase activity|,9,-0.8,15.9,9,-1.7,10.5,-0.9,22.5,-22.5,0.0267,0,0,-2.3,-0.6
ENSMUSG00000071662,POLR2G,polymerase (RNA) II (DNA directed) polypeptide G,"cytoplasmic mRNA processing body|nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|","nuclear-transcribed mRNA catabolic process, exonucleolytic|transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|positive regulation of translational initiation|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|",single-stranded DNA binding|RNA binding|single-stranded RNA binding|DNA-directed RNA polymerase activity|transferase activity|nucleotidyltransferase activity|translation initiation factor binding|,5,3.3,24.1,4,0.5,1.43,3.3,22.3,22.3,0.0278,0,0,2.6,6
ENSMUSG00000024137,E4F1,E4F transcription factor 1,nucleus|nucleus|cytoplasm|spindle|,"negative regulation of transcription from RNA polymerase II promoter|DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|mitotic nuclear division|embryo development|regulation of mitotic cell cycle, embryonic|regulation of cell cycle process|regulation of cell cycle process|regulation of growth|cell division|","RNA polymerase II regulatory region sequence-specific DNA binding|nucleic acid binding|DNA binding|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|cAMP response element binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,2.6,25.2,9,0,0,2.6,22.2,22.2,0.0284,0,0,1.5,5
ENSMUSG00000006373,PGRMC1,progesterone receptor membrane component 1,nucleolus|endoplasmic reticulum|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,None,steroid binding|lipid binding|heme binding|,10,0.3,1.68,10,2.5,23.2,0.5,22,22,0.0295,0,0,0.2,4.6
ENSMUSG00000031751,AMFR,autocrine motility factor receptor,Hrd1p ubiquitin ligase complex|nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|dendrite|growth cone|neuronal cell body|protein complex|perinuclear region of cytoplasm|,protein polyubiquitination|ubiquitin-dependent protein catabolic process|cellular process|ER-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum unfolded protein response|protein oligomerization|,"nucleotide binding|ubiquitin-protein transferase activity|receptor activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1,13.5,10,0.8,8.86,1,21.8,21.8,0.0306,0,0,0.6,1.7
ENSMUSG00000039159,UBE2H,ubiquitin-conjugating enzyme E2H,None,protein K48-linked ubiquitination|protein K11-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0.2,0.0624,10,1.6,23.8,1.6,21.6,21.6,0.0317,0,0,0.9,2.7
ENSMUSG00000056228,CARS2,cysteinyl-tRNA synthetase 2 (mitochondrial)(putative),mitochondrion|cytosol|,translation|tRNA aminoacylation for protein translation|cysteinyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA ligase activity|cysteine-tRNA ligase activity|ATP binding|ligase activity|metal ion binding|,8,1.4,10,8,1.3,11.9,1.4,21.5,21.5,0.0323,0,0,0.8,2.3
ENSMUSG00000037725,CKAP2,cytoskeleton associated protein 2,cytoplasm|centrosome|cytoskeleton|microtubule|cytoplasmic microtubule|cytoplasmic microtubule|,mitotic cytokinesis|apoptotic process|negative regulation of microtubule depolymerization|cell cycle|positive regulation of transcription from RNA polymerase II promoter|,molecular_function|,10,-0.4,3.02,10,-1.9,22.4,-1.8,21.5,-21.5,0.0323,0,0,-2.9,-0.4
ENSMUSG00000036893,EHMT1,euchromatic histone methyltransferase 1,nucleus|nucleus|chromosome|cytoplasm|plasma membrane|,"negative regulation of transcription from RNA polymerase II promoter|DNA methylation|embryo development|chromatin modification|histone methylation|peptidyl-lysine methylation|peptidyl-lysine monomethylation|peptidyl-lysine dimethylation|peptidyl-lysine dimethylation|methylation|histone lysine methylation|negative regulation of transcription, DNA-templated|histone H3-K9 methylation|histone H3-K27 methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|p53 binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|zinc ion binding|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|histone methyltransferase activity (H3-K9 specific)|histone methyltransferase activity (H3-K9 specific)|histone methyltransferase activity (H3-K27 specific)|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|C2H2 zinc finger domain binding|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.8,8.05,10,0.8,13.8,0.8,21.5,21.5,0.0323,0,0,0.5,1.4
ENSMUSG00000032244,FEM1B,feminization 1 homolog b (C. elegans),nucleus|nucleus|cytoplasm|,epithelial cell maturation|apoptotic process|protein ubiquitination|protein ubiquitination|regulation of ubiquitin-protein transferase activity|branching involved in prostate gland morphogenesis|epithelial cell maturation involved in prostate gland development|regulation of extrinsic apoptotic signaling pathway via death domain receptors|regulation of DNA damage checkpoint|,ubiquitin-protein transferase activity|death receptor binding|protein binding|,10,1.5,6.21,10,1,16.2,1,21.3,21.3,0.0334,0,0,0.6,1.9
ENSMUSG00000030451,HERC2,hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2,nucleus|nucleus|cytoplasm|mitochondrial inner membrane|cytoskeleton|membrane|,DNA repair|cellular response to DNA damage stimulus|spermatogenesis|protein ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|heme binding|ubiquitin protein ligase binding|SUMO binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-1.5,15.3,9,-1,7.43,-1.2,21.3,-21.3,0.0334,0,0,-2,-0.4
ENSMUSG00000027905,DDX20,DEAD (Asp-Glu-Ala-Asp) box polypeptide 20,nucleus|cytoplasm|cytosol|membrane|transcriptional repressor complex|SMN complex|SMN-Sm protein complex|,"negative regulation of transcription from RNA polymerase II promoter|spliceosomal snRNP assembly|mRNA processing|RNA splicing|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of transcription, DNA-templated|oogenesis|regulation of steroid biosynthetic process|",nucleotide binding|nucleic acid binding|DNA binding|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|protein domain specific binding|,9,1.3,22,9,-0.4,1.74,1.2,21.2,21.2,0.0339,0,0,0.7,2.1
ENSMUSG00000024791,CDCA5,cell division cycle associated 5,chromatin|nuclear chromatin|nucleus|nucleus|chromosome|cytoplasm|plasma membrane|cohesin complex|cohesin complex|,G1/S transition of mitotic cell cycle|double-strand break repair|cell cycle|mitotic sister chromatid cohesion|mitotic sister chromatid cohesion|mitotic nuclear division|mitotic nuclear division|mitotic chromosome condensation|mitotic metaphase plate congression|cell division|mitotic interphase|regulation of cohesin localization to chromatin|,protein binding|,9,0.3,0.995,9,1.1,22.6,1.1,21.1,21.1,0.0345,0,0,0.6,1.8
ENSMUSG00000044702,PALB2,partner and localizer of BRCA2,nucleus|,double-strand break repair via homologous recombination|somitogenesis|inner cell mass cell proliferation|DNA repair|DNA recombination|cellular response to DNA damage stimulus|mesoderm development|organ morphogenesis|post-anal tail morphogenesis|negative regulation of apoptotic process|,DNA binding|,8,0.5,3.41,7,3,23.3,2.9,21.1,21.1,0.0345,0,0,2,5
ENSMUSG00000059060,RAD51B,RAD51 homolog B,nucleus|replication fork|Rad51B-Rad51C-Rad51D-XRCC2 complex|,double-strand break repair via homologous recombination|ATP catabolic process|DNA metabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|positive regulation of G2/M transition of mitotic cell cycle|,nucleotide binding|four-way junction DNA binding|DNA binding|double-stranded DNA binding|single-stranded DNA binding|ATP binding|DNA-dependent ATPase activity|,10,1.7,18.5,10,0.7,4.88,0.9,21,21,0.0349,0,0,0.5,2.4
ENSMUSG00000078813,LENG1,leukocyte receptor cluster (LRC) member 1,cellular_component|,biological_process|,molecular_function|,10,2.4,23.7,10,-0.6,1.2,2.1,20.8,20.8,0.0364,0,0,0.6,4
ENSMUSG00000051238,SWSAP1,SWIM type zinc finger 7 associated protein 1,nucleus|Shu complex|,double-strand break repair via homologous recombination|ATP catabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|protein stabilization|,DNA binding|single-stranded DNA binding|ATPase activity|,10,0.7,8.41,10,1,13.5,0.7,20.7,20.7,0.0369,0,0,0.5,1.4
ENSMUSG00000025153,FASN,fatty acid synthase,cytoplasm|mitochondrion|Golgi apparatus|plasma membrane|membrane|glycogen granule|extracellular vesicular exosome|,osteoblast differentiation|acetyl-CoA metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|metabolic process|biosynthetic process|oxidation-reduction process|cellular response to interleukin-4|,"catalytic activity|fatty acid synthase activity|[acyl-carrier-protein] S-acetyltransferase activity|[acyl-carrier-protein] S-malonyltransferase activity|3-oxoacyl-[acyl-carrier-protein] synthase activity|3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity|3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity|enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity|oleoyl-[acyl-carrier-protein] hydrolase activity|drug binding|zinc ion binding|myristoyl-[acyl-carrier-protein] hydrolase activity|palmitoyl-[acyl-carrier-protein] hydrolase activity|acyl-[acyl-carrier-protein] hydrolase activity|oxidoreductase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|hydrolase activity|hydrolase activity, acting on ester bonds|lyase activity|3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity|identical protein binding|protein homodimerization activity|poly(A) RNA binding|enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity|3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity|NADPH binding|",10,-0.8,11,10,-0.7,10.2,-0.8,20.7,-20.7,0.0369,0,0,-1.3,-0.4
ENSMUSG00000015656,HSPA8,heat shock protein 8,Prp19 complex|extracellular space|intracellular|nucleus|spliceosomal complex|nucleolus|cytoplasm|cytosol|cytosol|plasma membrane|synaptic vesicle|membrane|membrane|ribonucleoprotein complex|neuron projection|neuronal cell body|protein complex|extracellular vesicular exosome|extracellular vesicular exosome|blood microparticle|,"ATP catabolic process|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|protein folding|response to stress|RNA splicing|protein refolding|negative regulation of transcription, DNA-templated|chaperone mediated protein folding requiring cofactor|chaperone mediated protein folding requiring cofactor|regulation of cell cycle|chaperone-mediated protein folding|clathrin coat disassembly|negative regulation of fibril organization|","nucleotide binding|receptor binding|protein binding|ATP binding|ATPase activity|enzyme binding|MHC class II protein complex binding|heat shock protein binding|ATPase activity, coupled|ATPase activity, coupled|ADP binding|poly(A) RNA binding|unfolded protein binding|unfolded protein binding|",5,2.3,21.2,7,0.9,1.99,2,20.6,20.6,0.0376,0,0,1.1,4
ENSMUSG00000030662,IPO5,importin 5,nucleus|nucleus|cytoplasm|cytoplasm|Golgi apparatus|membrane|nuclear membrane|intracellular membrane-bounded organelle|,NLS-bearing protein import into nucleus|ribosomal protein import into nucleus|transport|intracellular protein transport|protein transport|positive regulation of protein import into nucleus|cellular response to amino acid stimulus|,protein binding|Ran GTPase binding|protein transporter activity|poly(A) RNA binding|,10,0.9,15,10,0.6,6.72,0.9,20.6,20.6,0.0376,0,0,0.5,1.4
ENSMUSG00000026683,NUF2,"NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)","chromosome, centromeric region|kinetochore|nucleus|chromosome|membrane|Ndc80 complex|",cell cycle|mitotic nuclear division|attachment of spindle microtubules to kinetochore|cell division|,molecular_function|,7,2.8,23.4,8,0.3,1.16,2.8,20.5,20.5,0.0384,0,0,2,5
ENSMUSG00000027326,CASC5,cancer susceptibility candidate 5,"chromosome, centromeric region|kinetochore|acrosomal vesicle|nucleus|chromosome|cytoplasm|extracellular vesicular exosome|",cell cycle|chromosome segregation|mitotic nuclear division|attachment of spindle microtubules to kinetochore|negative regulation of phosphatase activity|protein localization to kinetochore|cell division|spindle assembly checkpoint|,molecular_function|,10,1,18.2,10,0.4,3.98,0.9,20.5,20.5,0.0384,0,0,0.6,1.6
ENSMUSG00000013629,CAD,"carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase",nucleus|cytoplasm|cytosol|membrane|nuclear matrix|cell projection|neuronal cell body|terminal bouton|protein complex|extracellular vesicular exosome|,'de novo' pyrimidine nucleobase biosynthetic process|pyrimidine nucleotide biosynthetic process|UTP biosynthetic process|cellular amino acid metabolic process|glutamine catabolic process|nitrogen compound metabolic process|metabolic process|drug metabolic process|peptidyl-threonine phosphorylation|protein autophosphorylation|carbamoyl phosphate biosynthetic process|,"nucleotide binding|UTP binding|catalytic activity|aspartate carbamoyltransferase activity|carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity|dihydroorotase activity|protein kinase activity|ATP binding|zinc ion binding|amino acid binding|transferase activity|carboxyl- or carbamoyltransferase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|ligase activity|enzyme binding|identical protein binding|metal ion binding|",6,1.1,12,5,1,8.75,1,20.4,20.4,0.039,0,0,0.6,1.7
ENSMUSG00000040549,CKAP5,cytoskeleton associated protein 5,spindle pole|gamma-tubulin complex|cytoplasm|centrosome|cytoskeleton|membrane|microtubule plus-end|protein complex|,cell cycle|spindle organization|mitotic nuclear division|establishment or maintenance of microtubule cytoskeleton polarity|centrosome organization|cell division|,microtubule binding|ribonucleoprotein complex binding|,9,0.3,1.56,9,-2.1,23,-2.1,20.4,-20.4,0.039,0,0,-4,-1.2
ENSMUSG00000034192,LSM3,"LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)",nucleus|spliceosomal complex|ribonucleoprotein complex|U4/U6 x U5 tri-snRNP complex|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",RNA binding|U6 snRNA 3'-end binding|poly(A) RNA binding|,4,1.7,3.52,5,1.2,17.5,1.4,20.1,20.1,0.0415,0,0,0.9,2.7
ENSMUSG00000020166,CNOT2,"CCR4-NOT transcription complex, subunit 2",nucleus|cytoplasm|membrane|CCR4-NOT complex|,"negative regulation of transcription from RNA polymerase II promoter|trophectodermal cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|multicellular organismal development|positive regulation of cytoplasmic mRNA processing body assembly|gene silencing by RNA|negative regulation of intracellular estrogen receptor signaling pathway|RNA phosphodiester bond hydrolysis, exonucleolytic|regulation of stem cell maintenance|regulation of stem cell maintenance|",RNA polymerase II transcription corepressor binding|poly(A)-specific ribonuclease activity|,10,-0.6,13.2,10,-0.5,7.58,-0.6,20,-20,0.0424,0,0,-0.9,-0.3
ENSMUSG00000022674,UBE2V2,ubiquitin-conjugating enzyme E2 variant 2,nucleus|UBC13-MMS2 complex|extracellular vesicular exosome|,DNA double-strand break processing|positive regulation of neuron projection development|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|error-free postreplication DNA repair|negative regulation of neuron apoptotic process|positive regulation of DNA repair|positive regulation of synapse assembly|,protein binding|acid-amino acid ligase activity|,9,2.8,23.4,9,-0.5,2.49,2.8,19.9,19.9,0.0433,0,0,2,5
ENSMUSG00000022471,XRCC6,X-ray repair complementing defective repair in Chinese hamster cells 6,nucleus|nucleus|transcription factor complex|chromosome|nucleolus|cytoplasm|cytoplasm|membrane|protein complex|Ku70:Ku80 complex|nonhomologous end joining complex|,"telomere maintenance|DNA repair|double-strand break repair|double-strand break repair via nonhomologous end joining|double-strand break repair via nonhomologous end joining|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|metabolic process|response to ionizing radiation|V(D)J recombination|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of neurogenesis|cellular hyperosmotic salinity response|cellular response to X-ray|",nucleotide binding|nucleic acid binding|DNA binding|damaged DNA binding|double-stranded DNA binding|double-stranded telomeric DNA binding|catalytic activity|ATP-dependent DNA helicase activity|helicase activity|ATP binding|protein C-terminus binding|hydrolase activity|lyase activity|telomeric DNA binding|transcription regulatory region DNA binding|poly(A) RNA binding|5'-deoxyribose-5-phosphate lyase activity|,10,1.2,10.9,10,1,9.6,0.9,19.9,19.9,0.0433,0,0,0.5,1.7
ENSMUSG00000030538,CIB1,calcium and integrin binding 1 (calmyrin),nucleus|nucleoplasm|nucleoplasm|cytoplasm|cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|centrosome|cytoskeleton|plasma membrane|membrane|membrane|lamellipodium|growth cone|filopodium tip|sarcolemma|sarcolemma|cell projection|neuron projection|neuronal cell body|perinuclear region of cytoplasm|extracellular vesicular exosome|cell periphery|,angiogenesis|negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|positive regulation of cell-matrix adhesion|response to ischemia|apoptotic process|apoptotic process|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|negative regulation of microtubule depolymerization|cell cycle|endomitotic cell cycle|cell adhesion|integrin-mediated signaling pathway|spermatogenesis|spermatid development|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of neuron projection development|cell differentiation|platelet formation|positive regulation of cell growth|positive regulation of cell migration|cytoplasmic microtubule organization|positive regulation of cell adhesion mediated by integrin|thrombopoietin-mediated signaling pathway|regulation of cell proliferation|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of megakaryocyte differentiation|positive regulation of metalloenzyme activity|positive regulation of NF-kappaB transcription factor activity|cell division|regulation of cell division|negative regulation of protein kinase B signaling|positive regulation of ERK1 and ERK2 cascade|positive regulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signaling cascade|cellular response to tumor necrosis factor|cellular response to growth factor stimulus|positive regulation of protein serine/threonine kinase activity|positive regulation of establishment of protein localization to plasma membrane|positive regulation of establishment of protein localization to plasma membrane|positive regulation of cell migration involved in sprouting angiogenesis|positive regulation of protein targeting to membrane|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of gene expression involved in extracellular matrix organization|cellular response to nerve growth factor stimulus|positive regulation of male germ cell proliferation|,calcium ion binding|calcium ion binding|protein binding|Ras GTPase binding|protein anchor|protein anchor|ion channel binding|metal ion binding|,10,0.6,7.81,10,0.7,12.4,0.6,19.7,19.7,0.045,0,0,0.4,1.1
ENSMUSG00000034021,PDS5B,"PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)",chromatin|nucleus|,cell cycle|mitotic sister chromatid cohesion|mitotic nuclear division|negative regulation of cell proliferation|regulation of cell proliferation|cell division|,DNA binding|,10,-2.1,22.8,10,0.4,4.69,-2.1,19.6,-19.6,0.046,0,0,-4,-1.2
ENSMUSG00000026708,CENPL,centromere protein L,"chromosome, centromeric region|cellular_component|nucleus|chromosome|",biological_process|,molecular_function|,9,1.3,8.97,8,1.2,10.8,1.2,19.4,19.4,0.0483,0,0,0.8,2.4
ENSMUSG00000043962,THRAP3,thyroid hormone receptor associated protein 3,nucleus|mediator complex|mediator complex|exon-exon junction complex|,"regulation of alternative mRNA splicing, via spliceosome|nuclear-transcribed mRNA catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|mRNA processing|RNA splicing|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of mRNA splicing, via spliceosome|mRNA stabilization|",nucleotide binding|RNA polymerase II transcription cofactor activity|transcription cofactor activity|transcription coactivator activity|receptor activity|ATP binding|poly(A) RNA binding|thyroid hormone receptor binding|phosphoprotein binding|,10,0.9,15,10,1.4,5.29,0.9,19.4,19.4,0.0483,0,0,0.6,1.8
ENSMUSG00000039191,RBPJ,recombination signal binding protein for immunoglobulin kappa J region,MAML1-RBP-Jkappa- ICN1 complex|cell|nucleus|nucleus|nucleus|nucleus|transcription factor complex|nucleolus|cytoplasm|protein-DNA complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|angiogenesis|somitogenesis|somitogenesis|epithelial to mesenchymal transition|heart looping|blood vessel remodeling|inflammatory response to antigenic stimulus|secondary heart field specification|secondary heart field specification|outflow tract morphogenesis|endocardium development|endocardium morphogenesis|epithelial to mesenchymal transition involved in endocardial cushion formation|cardiac left ventricle morphogenesis|ventricular trabecula myocardium morphogenesis|regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|humoral immune response|Notch signaling pathway|Notch signaling pathway|positive regulation of transcription of Notch receptor target|positive regulation of transcription of Notch receptor target|heart development|positive regulation of cell proliferation|negative regulation of cell proliferation|auditory receptor cell fate commitment|epidermal cell fate specification|regulation of gene expression|positive regulation of gene expression|negative regulation of neuron projection development|negative regulation of smooth muscle cell migration|pituitary gland development|hemopoiesis|neuron differentiation|B cell differentiation|keratinocyte differentiation|negative regulation of ossification|positive regulation of BMP signaling pathway|negative regulation of smooth muscle cell apoptotic process|somatic stem cell maintenance|positive regulation of Notch signaling pathway involved in heart induction|dorsal aorta morphogenesis|atrioventricular canal development|defense response to bacterium|myeloid dendritic cell differentiation|cell fate commitment|negative regulation of cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of timing of cell differentiation|positive regulation of smooth muscle cell proliferation|sebaceous gland development|hair follicle maturation|positive regulation of cardiac muscle cell proliferation|Clara cell differentiation|labyrinthine layer blood vessel development|arterial endothelial cell fate commitment|Notch signaling pathway involved in arterial endothelial cell fate commitment|regulation of cell adhesion involved in heart morphogenesis|determination of heart left/right asymmetry|blood vessel lumenization|interleukin-4 secretion|blood vessel endothelial cell fate specification|positive regulation of ERBB signaling pathway|positive regulation of ephrin receptor signaling pathway|positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment|positive regulation of cell proliferation involved in heart morphogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II repressing transcription factor binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein complex binding|sequence-specific DNA binding|protein N-terminus binding|,10,1.1,10.4,10,0.9,9.55,1,19.3,19.3,0.0494,0,0,0.5,1.6
ENSMUSG00000038738,SHANK1,SH3/ankyrin domain gene 1,cytoplasm|plasma membrane|ionotropic glutamate receptor complex|membrane|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|dendrite|neuron projection|dendritic spine|dendritic spine|synapse|postsynaptic membrane|postsynaptic membrane|postsynaptic membrane|excitatory synapse|neuronal postsynaptic density|,protein complex assembly|nervous system development|long-term memory|associative learning|cell differentiation|adult behavior|negative regulation of actin filament bundle assembly|social behavior|social behavior|protein localization to synapse|olfactory behavior|habituation|neuromuscular process controlling balance|determination of affect|righting reflex|synapse maturation|dendritic spine morphogenesis|positive regulation of dendritic spine development|vocalization behavior|vocalization behavior|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|positive regulation of excitatory postsynaptic membrane potential|,protein C-terminus binding|SH3 domain binding|receptor signaling complex scaffold activity|GKAP/Homer scaffold activity|GKAP/Homer scaffold activity|somatostatin receptor binding|protein complex binding|ionotropic glutamate receptor binding|ionotropic glutamate receptor binding|identical protein binding|ankyrin repeat binding|scaffold protein binding|,10,0,0,10,2.9,22.8,2.9,19.2,19.2,0.0506,0,0,2.3,5
ENSMUSG00000027087,ITGAV,integrin alpha V,intracellular|nucleus|plasma membrane|plasma membrane|integrin complex|external side of plasma membrane|cell surface|membrane|integral component of membrane|integrin alphav-beta3 complex|alphav-beta3 integrin-IGF-1-IGF1R complex|extracellular vesicular exosome|,angiogenesis|blood vessel development|cellular calcium ion homeostasis|inflammatory response|cell adhesion|cell-matrix adhesion|positive regulation of cytosolic calcium ion concentration|integrin-mediated signaling pathway|multicellular organismal development|positive regulation of cell proliferation|fertilization|negative regulation of macrophage derived foam cell differentiation|negative regulation of lipid storage|cell migration|cell differentiation|positive regulation of cell migration|cell-substrate adhesion|negative regulation of lipid transport|detection of molecule of bacterial origin|positive regulation of osteoblast proliferation|regulation of ion transmembrane transport|gonad morphogenesis|T cell activation|apoptotic cell clearance|positive regulation of MAPK cascade|endothelial cell migration|regulation of bone resorption|negative regulation of low-density lipoprotein particle receptor biosynthetic process|positive regulation of cell adhesion|focal adhesion assembly|negative regulation of lipoprotein metabolic process|regulation of phagocytosis|regulation of phagocytosis|release of sequestered calcium ion into cytosol|trophoblast giant cell differentiation|ERK1 and ERK2 cascade|calcium ion transmembrane transport|response to nitric oxide|extrinsic apoptotic signaling pathway in absence of ligand|regulation of apoptotic cell clearance|negative regulation of entry of bacterium into host cell|negative regulation of extrinsic apoptotic signaling pathway|,opsonin binding|protein kinase C binding|receptor binding|voltage-gated calcium channel activity|insulin-like growth factor I binding|peptide binding|metal ion binding|protein heterodimerization activity|,10,-0.8,14.6,10,-0.5,6.07,-0.7,19.2,-19.2,0.0506,0,0,-1.2,-0.4
ENSMUSG00000007659,BCL2L1,BCL2-like 1,intracellular|intracellular|nucleus|nucleolus|cytoplasm|mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial outer membrane|mitochondrial outer membrane|mitochondrial outer membrane|mitochondrial inner membrane|centrosome|cytosol|cytoskeleton|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|mitochondrial membrane|synapse|Bcl-2 family protein complex|,cytokinesis|ovarian follicle development|ovarian follicle development|ovarian follicle development|in utero embryonic development|release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|response to ischemia|apoptotic process|mitotic cell cycle checkpoint|germ cell development|germ cell development|spermatogenesis|cell proliferation|positive regulation of cell proliferation|male gonad development|intrinsic apoptotic signaling pathway in response to DNA damage|response to radiation|fertilization|response to virus|suppression by virus of host apoptotic process|response to cytokine|growth|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|response to cycloheximide|regulation of mitochondrial membrane permeability|neuron apoptotic process|neuron apoptotic process|regulation of mitochondrial membrane potential|cellular process regulating host cell cycle in response to virus|mitochondrion morphogenesis|cellular response to amino acid stimulus|cellular response to alkaloid|cellular response to gamma radiation|apoptotic process in bone marrow|negative regulation of establishment of protein localization to plasma membrane|negative regulation of release of cytochrome c from mitochondria|extrinsic apoptotic signaling pathway in absence of ligand|hepatocyte apoptotic process|negative regulation of execution phase of apoptosis|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of anoikis|negative regulation of intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway|,protein binding|protein kinase binding|identical protein binding|protein homodimerization activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|protein heterodimerization activity|protein heterodimerization activity|BH domain binding|BH3 domain binding|MDM2/MDM4 family protein binding|,10,-0.7,13.3,10,-0.6,6.3,-0.7,19,-19,0.0532,0,0,-1.1,-0.4
ENSMUSG00000027845,DCLRE1B,"DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)","chromosome, telomeric region|chromosome, telomeric region|nucleus|chromosome|cytoplasm|centrosome|cytoskeleton|",cell cycle checkpoint|telomere maintenance|DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|telomeric loop formation|protection from non-homologous end joining at telomere|protection from non-homologous end joining at telomere|telomeric 3' overhang formation|nucleic acid phosphodiester bond hydrolysis|nucleic acid phosphodiester bond hydrolysis|,nuclease activity|exonuclease activity|protein binding|5'-3' exonuclease activity|5'-3' exonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,1.7,10.1,10,1,10.5,1.2,18.9,18.9,0.0545,0,0,0.6,2.4
ENSMUSG00000026942,TRAF2,TNF receptor-associated factor 2,cytoplasm|cytosol|cell cortex|cytoplasmic side of plasma membrane|CD40 receptor complex|protein complex|membrane raft|membrane raft|,positive regulation of T cell cytokine production|protein complex assembly|apoptotic process|signal transduction|activation of NF-kappaB-inducing kinase activity|protein catabolic process|positive regulation of interleukin-2 production|tumor necrosis factor-mediated signaling pathway|negative regulation of glial cell apoptotic process|regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of JUN kinase activity|cellular protein complex assembly|regulation of JNK cascade|regulation of immunoglobulin secretion|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein heterooligomerization|protein autoubiquitination|protein homotrimerization|protein K63-linked ubiquitination|cellular response to nitric oxide|positive regulation of protein homodimerization activity|programmed necrotic cell death|positive regulation of extrinsic apoptotic signaling pathway|,"ubiquitin-protein transferase activity|receptor binding|tumor necrosis factor receptor binding|CD40 receptor binding|protein binding|zinc ion binding|lipid binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|enzyme binding|protein phosphatase binding|mitogen-activated protein kinase kinase kinase binding|ubiquitin protein ligase binding|thioesterase binding|protein complex binding|identical protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|sphingolipid binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.8,18,10,1.3,3.15,-0.7,18.9,-18.9,0.0545,0,0,-1.3,-0.4
ENSMUSG00000036751,COX6B1,"cytochrome c oxidase, subunit VIb polypeptide 1",mitochondrion|mitochondrion|mitochondrial inner membrane|,None,cytochrome-c oxidase activity|,10,-0.6,11.5,10,-0.5,7.73,-0.6,18.8,-18.8,0.0558,0,0,-1.1,-0.4
ENSMUSG00000031878,NAE1,NEDD8 activating enzyme E1 subunit 1,nucleus|cytosol|plasma membrane|membrane|,apoptotic process|cell cycle|mitotic DNA replication checkpoint|regulation of apoptotic process|regulation of neuron apoptotic process|protein neddylation|protein neddylation|neuron apoptotic process|,catalytic activity|NEDD8 activating enzyme activity|NEDD8 activating enzyme activity|ubiquitin protein ligase binding|protein heterodimerization activity|,9,-0.7,9.91,10,-0.7,9.19,-0.7,18.7,-18.7,0.057,0,0,-1.1,-0.4
ENSMUSG00000040282,BC052040,cDNA sequence BC052040,cellular_component|,biological_process|,molecular_function|,9,1,9.48,9,0.8,9.94,0.9,18.5,18.5,0.0598,0,0,0.6,1.6
ENSMUSG00000028899,TAF12,"TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor",PCAF complex|nucleus|transcription factor TFIID complex|STAGA complex|STAGA complex|transcription factor TFTC complex|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|histone H3 acetylation|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of RNA biosynthetic process|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|histone acetyltransferase activity|protein binding|transcription factor binding|protein heterodimerization activity|,9,0.4,0.551,10,1,19.5,0.9,18.4,18.4,0.0612,0,0,0.5,2.1
ENSMUSG00000054499,DEDD2,death effector domain-containing DNA binding protein 2,nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|extrinsic apoptotic signaling pathway via death domain receptors|apoptotic nuclear changes|regulation of apoptotic process|positive regulation of extrinsic apoptotic signaling pathway|",molecular_function|DNA binding|,10,-0.4,3.62,10,2.8,21.5,2.8,18.2,18.2,0.064,0,0,2.2,5
ENSMUSG00000032407,U2SURP,U2 snRNP-associated SURP domain containing,nucleus|,RNA processing|biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,9,-1.1,9.65,10,-0.6,11.5,-0.9,18.2,-18.2,0.064,0,0,-1.5,-0.5
ENSMUSG00000022710,USP7,ubiquitin specific peptidase 7,nucleus|nucleus|cytoplasm|cytosol|,DNA repair|transcription-coupled nucleotide-excision repair|proteolysis|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|multicellular organismal development|maintenance of DNA methylation|protein deubiquitination|protein deubiquitination|regulation of protein stability|negative regulation of NF-kappaB transcription factor activity|positive regulation of apoptotic process|regulation of sequence-specific DNA binding transcription factor activity|,p53 binding|cysteine-type endopeptidase activity|cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|ubiquitin-specific protease activity|protein binding|protein C-terminus binding|transcription factor binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitin protein ligase binding|ubiquitinyl hydrolase activity|protein homodimerization activity|,8,2.3,20.9,7,-1.1,9.23,2.3,18,18,0.0668,0,0,0.9,4
ENSMUSG00000022673,MCM4,minichromosome maintenance deficient 4 homolog (S. cerevisiae),nucleus|membrane|MCM complex|,DNA replication|DNA unwinding involved in DNA replication|DNA replication initiation|cell cycle|,nucleotide binding|DNA binding|DNA helicase activity|single-stranded DNA binding|ATP-dependent DNA helicase activity|helicase activity|protein binding|ATP binding|hydrolase activity|,9,-1.1,10,10,1.5,20.3,1.5,17.8,17.8,0.0687,0,0,0.7,2.6
ENSMUSG00000030983,BCCIP,BRCA2 and CDKN1A interacting protein,nucleus|nuclear cyclin-dependent protein kinase holoenzyme complex|,regulation of cyclin-dependent protein serine/threonine kinase activity|DNA repair|cellular response to DNA damage stimulus|cell cycle|neuroendocrine cell differentiation|,kinase regulator activity|poly(A) RNA binding|,9,-1.5,8.77,9,-1.7,9.63,-1.6,17.7,-17.7,0.0696,0,0,-2.8,-1.1
ENSMUSG00000037236,MATR3,matrin 3,nucleus|membrane|,None,nucleotide binding|nucleic acid binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.7,11.6,10,1.6,6.98,-0.7,17.5,-17.5,0.0714,0,0,-1.3,-0.4
ENSMUSG00000030793,PYCARD,PYD and CARD domain containing,extracellular region|nucleus|nucleus|nucleolus|cytoplasm|mitochondrion|endoplasmic reticulum|cytosol|IkappaB kinase complex|neuronal cell body|protein complex|NLRP1 inflammasome complex|NLRP3 inflammasome complex|AIM2 inflammasome complex|,myeloid dendritic cell activation|activation of innate immune response|activation of innate immune response|positive regulation of defense response to virus by host|myeloid dendritic cell activation involved in immune response|immune system process|positive regulation of antigen processing and presentation of peptide antigen via MHC class II|positive regulation of adaptive immune response|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|inflammatory response|regulation of tumor necrosis factor-mediated signaling pathway|positive regulation of actin filament polymerization|regulation of protein stability|negative regulation of NF-kappaB transcription factor activity|regulation of Rac GTPase activity|interleukin-1 beta production|negative regulation of interferon-beta production|positive regulation of interferon-gamma production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|tumor necrosis factor-mediated signaling pathway|positive regulation of activated T cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of cysteine-type endopeptidase activity involved in apoptotic process|macropinocytosis|innate immune response|positive regulation of JNK cascade|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|regulation of inflammatory response|positive regulation of phagocytosis|defense response to Gram-negative bacterium|positive regulation of T cell activation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|defense response to virus|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cellular response to lipopolysaccharide|cellular response to interleukin-1|cellular response to tumor necrosis factor|negative regulation of protein serine/threonine kinase activity|intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of chemokine secretion|positive regulation of chemokine secretion|positive regulation of release of cytochrome c from mitochondria|positive regulation of T cell migration|positive regulation of interleukin-8 secretion|positive regulation of interleukin-6 secretion|positive regulation of cysteine-type endopeptidase activity|positive regulation of interleukin-10 secretion|positive regulation of extrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway|,protease binding|protein binding|peptidase activator activity involved in apoptotic process|Pyrin domain binding|protein homodimerization activity|ion channel binding|,10,0.9,9,10,0.6,9.04,0.9,17.5,17.5,0.0714,0,0,0.5,1.6
ENSMUSG00000032076,CADM1,cell adhesion molecule 1,plasma membrane|plasma membrane|cell-cell junction|synaptic vesicle|membrane|integral component of membrane|basolateral plasma membrane|cell junction|axon|dendrite|neuron projection|synapse|extracellular vesicular exosome|,liver development|immune system process|apoptotic process|cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|multicellular organismal development|spermatogenesis|synapse assembly|cell recognition|cell recognition|unidimensional cell growth|calcium-independent cell-cell adhesion|cell differentiation|susceptibility to natural killer cell mediated cytotoxicity|susceptibility to natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of cytokine secretion|detection of stimulus|detection of stimulus|bone development|,receptor binding|receptor binding|protein binding|PDZ domain binding|protein homodimerization activity|cell adhesion molecule binding|,10,0.9,4.32,10,2.3,16.7,2.2,17.4,17.4,0.0721,0,0,0.8,3.6
ENSMUSG00000005054,CSTB,cystatin B,extracellular space|intracellular|nucleus|nucleolus|cytoplasm|extracellular vesicular exosome|,adult locomotory behavior|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of proteolysis|,protease binding|endopeptidase inhibitor activity|cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|poly(A) RNA binding|,9,-1.3,2.66,8,-1.7,15.7,-1.6,17.3,-17.3,0.0727,0,0,-3,-0.8
ENSMUSG00000029535,TRIAP1,TP53 regulated inhibitor of apoptosis 1,cytoplasm|mitochondrion|mitochondrion|mitochondrial intermembrane space|protein complex|,"transport|lipid transport|apoptotic process|phospholipid transport|DNA damage response, signal transduction by p53 class mediator|cellular response to UV|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of transcription from RNA polymerase II promoter|negative regulation of release of cytochrome c from mitochondria|regulation of membrane lipid distribution|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of phospholipid transport|",p53 binding|phosphatidic acid transporter activity|,6,-1.8,18.1,8,1.1,6.17,-1.8,17.1,-17.1,0.0742,0,0,-4,-0.6
ENSMUSG00000013089,ETV5,ets variant 5,nucleus|nucleus|,"regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|neuromuscular synaptic transmission|locomotory behavior|cell differentiation|cellular response to oxidative stress|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|male germ-line stem cell asymmetric division|regulation of synapse organization|positive regulation of glial cell proliferation|regulation of branching involved in mammary gland duct morphogenesis|skeletal muscle acetylcholine-gated channel clustering|",RNA polymerase II regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,-0.8,9.79,10,-1.1,8.57,-0.9,17.1,-17.1,0.0742,0,0,-1.6,-0.5
ENSMUSG00000052144,PPP4R2,"protein phosphatase 4, regulatory subunit 2",nucleus|nucleus|cytoplasm|cytoskeleton|protein phosphatase 4 complex|protein phosphatase 4 complex|,hematopoietic progenitor cell differentiation|mRNA processing|RNA splicing|regulation of double-strand break repair via homologous recombination|regulation of catalytic activity|,"protein binding|protein phosphatase type 4 regulator activity|protein binding, bridging|",10,1,5.08,10,1.6,12.9,1,16.8,16.8,0.0767,0,0,0.7,2.4
ENSMUSG00000027523,GNAS,"GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus",ruffle|extracellular region|nucleus|cytoplasm|endosome|cytosol|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|plasma membrane|membrane|membrane|membrane|dendrite|intrinsic component of membrane|cytoplasmic vesicle|vesicle|trans-Golgi network membrane|sarcolemma|cell projection|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,skeletal system development|tissue homeostasis|positive regulation of protein phosphorylation|endochondral ossification|energy reserve metabolic process|GTP catabolic process|DNA methylation|regulation of transcription from RNA polymerase II promoter|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|sensory perception of chemical stimulus|post-embryonic development|positive regulation of sodium ion transport|positive regulation of cAMP biosynthetic process|positive regulation of Ras GTPase activity|embryonic hindlimb morphogenesis|multicellular organism growth|negative regulation of renal sodium excretion|negative regulation of multicellular organism growth|post-embryonic body morphogenesis|response to drug|skin development|positive regulation of cAMP-mediated signaling|positive regulation of osteoblast differentiation|positive regulation of osteoclast differentiation|negative regulation of blood pressure|developmental growth|embryonic cranial skeleton morphogenesis|cognition|cartilage development|calcium ion homeostasis|bone development|hair follicle placode formation|platelet aggregation|response to parathyroid hormone|cellular response to prostaglandin E stimulus|genetic imprinting|cellular response to catecholamine stimulus|adenylate cyclase-activating adrenergic receptor signaling pathway|,nucleotide binding|G-protein alpha-subunit binding|GTPase activity|GTPase activity|GTPase activity|signal transducer activity|signal transducer activity|insulin-like growth factor receptor binding|insulin-like growth factor receptor binding|protein binding|GTP binding|guanyl nucleotide binding|protein domain specific binding|G-protein beta-subunit binding|G-protein beta/gamma-subunit complex binding|beta-2 adrenergic receptor binding|beta-2 adrenergic receptor binding|D1 dopamine receptor binding|D1 dopamine receptor binding|mu-type opioid receptor binding|mu-type opioid receptor binding|ionotropic glutamate receptor binding|ionotropic glutamate receptor binding|alpha-tubulin binding|metal ion binding|corticotropin-releasing hormone receptor 1 binding|corticotropin-releasing hormone receptor 1 binding|,10,0.7,5.65,10,0.9,11.7,0.9,16.5,16.5,0.0793,0,0,0.5,1.5
ENSMUSG00000028274,RNGTT,RNA guanylyltransferase and 5'-phosphatase,nucleus|,7-methylguanosine mRNA capping|RNA processing|mRNA processing|protein dephosphorylation|metabolic process|dephosphorylation|,nucleotide binding|catalytic activity|mRNA guanylyltransferase activity|polynucleotide 5'-phosphatase activity|protein tyrosine phosphatase activity|GTP binding|protein tyrosine/serine/threonine phosphatase activity|RNA guanylyltransferase activity|transferase activity|nucleotidyltransferase activity|hydrolase activity|phosphatase activity|triphosphatase activity|,7,-1,14.9,7,-1.2,2.33,-1.1,16.5,-16.5,0.0793,0,0,-1.9,-0.7
ENSMUSG00000025024,SMNDC1,survival motor neuron domain containing 1,nucleus|spliceosomal complex|cytoplasm|intermediate filament cytoskeleton|,mRNA processing|apoptotic process|biological_process|RNA splicing|,RNA binding|poly(A) RNA binding|,8,0.9,8.41,9,0.6,8.75,0.9,16.4,16.4,0.0801,0,0,0.5,1.7
ENSMUSG00000018800,ABCA5,"ATP-binding cassette, sub-family A (ABC1), member 5",lysosome|endosome|late endosome|Golgi apparatus|membrane|integral component of membrane|,transport|negative regulation of macrophage derived foam cell differentiation|cholesterol efflux|high-density lipoprotein particle remodeling|reverse cholesterol transport|,nucleotide binding|ATP binding|ATPase activity|,10,1.2,7.43,10,2.3,11.9,2.2,16.3,16.3,0.0809,0,0,1.1,3.8
ENSMUSG00000031516,DCTN6,dynactin 6,"chromosome, centromeric region|kinetochore|chromosome|cytoplasm|mitochondrion|centrosome|cytoskeleton|dynactin complex|",mitochondrion organization|mitotic spindle organization|lipid biosynthetic process|,catalytic activity|dynein binding|,8,-1,10.7,9,-0.7,5.83,-0.8,16,-16,0.0829,0,0,-1.5,-0.5
ENSMUSG00000038628,POLR3K,polymerase (RNA) III (DNA directed) polypeptide K,nucleus|DNA-directed RNA polymerase III complex|,"immune system process|transcription, DNA-templated|termination of RNA polymerase III transcription|innate immune response|defense response to virus|",RNA polymerase III activity|nucleic acid binding|DNA binding|DNA-directed RNA polymerase activity|zinc ion binding|metal ion binding|,8,1.6,18.2,7,-1,2.62,1.6,15.8,15.8,0.0837,0,0,1,2.9
ENSMUSG00000020074,CCAR1,cell division cycle and apoptosis regulator 1,nuclear envelope lumen|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cell cycle|positive regulation of apoptotic process|regulation of RNA biosynthetic process|",nucleic acid binding|ligand-dependent nuclear receptor transcription coactivator activity|poly(A) RNA binding|,10,1.1,13.3,10,1.3,3.13,1.2,15.8,15.8,0.0837,0,0,0.7,1.9
ENSMUSG00000033392,CLASP2,CLIP associating protein 2,"chromosome, centromeric region|kinetochore|chromosome|cytoplasm|Golgi apparatus|Golgi apparatus|trans-Golgi network|cytoskeleton|microtubule|cytoplasmic microtubule|cytoplasmic microtubule|plasma membrane|cell cortex|membrane|membrane|ruffle membrane|cell projection|",microtubule nucleation|negative regulation of microtubule depolymerization|negative regulation of microtubule depolymerization|negative regulation of microtubule depolymerization|cell cycle|mitotic nuclear division|meiotic nuclear division|establishment or maintenance of cell polarity|cell migration|microtubule organizing center organization|regulation of microtubule polymerization or depolymerization|regulation of microtubule-based process|microtubule anchoring|cell division|,protein binding|microtubule binding|microtubule binding|microtubule plus-end binding|,10,0.9,7.77,10,1.6,9.68,1.2,15.5,15.5,0.0849,0,0,0.6,2.3
ENSMUSG00000057406,WHSC1,Wolf-Hirschhorn syndrome candidate 1 (human),nucleus|nucleus|chromosome|nucleolus|nuclear membrane|,"negative regulation of transcription from RNA polymerase II promoter|membranous septum morphogenesis|atrial septum primum morphogenesis|atrial septum secundum morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|peptidyl-lysine methylation|methylation|histone lysine methylation|bone development|",DNA binding|chromatin binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|metal ion binding|,10,1.5,15.7,10,0.4,1.93,1.4,15.2,15.2,0.0862,0,0,0.6,2.4
ENSMUSG00000036707,CAB39,calcium binding protein 39,intracellular|cytoplasm|extracellular vesicular exosome|,peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|signal transduction by phosphorylation|activation of protein kinase activity|intracellular signal transduction|positive regulation of protein serine/threonine kinase activity|,protein serine/threonine kinase activity|calcium ion binding|kinase binding|protein kinase activator activity|protein serine/threonine kinase activator activity|,7,-0.3,1.72,8,1.5,17.5,1.4,15.2,15.2,0.0862,0,0,0.6,2.6
ENSMUSG00000032218,CCNB2,cyclin B2,nucleus|centrosome|microtubule cytoskeleton|membrane|,regulation of cyclin-dependent protein serine/threonine kinase activity|in utero embryonic development|cell cycle|mitotic nuclear division|growth|T cell homeostasis|thymus development|cell division|regulation of cell cycle|,protein kinase binding|,10,1,9.53,10,0.9,6.14,1,15.1,15.1,0.0867,0,0,0.5,1.6
ENSMUSG00000003360,DDX23,DEAD (Asp-Glu-Ala-Asp) box polypeptide 23,nucleus|U5 snRNP|mitochondrion|plasma membrane|U4/U6 x U5 tri-snRNP complex|extracellular vesicular exosome|catalytic step 2 spliceosome|,None,nucleotide binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,0.8,5.8,10,0.9,9.69,0.8,15,15,0.0871,0,0,0.4,1.4
ENSMUSG00000026872,ZEB2,zinc finger E-box binding homeobox 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|neural crest cell migration|somitogenesis|neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|central nervous system development|hippocampus development|cell proliferation in forebrain|positive regulation of Wnt signaling pathway|positive regulation of JUN kinase activity|positive regulation of transcription from RNA polymerase II promoter|embryonic morphogenesis|",nucleic acid binding|DNA binding|metal ion binding|R-SMAD binding|,9,-1.2,7.35,8,-0.9,8.79,-1.1,14.9,-14.9,0.0875,0,0,-1.8,-0.7
ENSMUSG00000020745,PAFAH1B1,"platelet-activating factor acetylhydrolase, isoform 1b, subunit 1",astral microtubule|kinetochore|intracellular|cell|nucleus|nuclear envelope|nuclear envelope|cytoplasm|centrosome|centrosome|cytosol|cytoskeleton|kinesin complex|microtubule|microtubule associated complex|microtubule associated complex|cell cortex|microtubule cytoskeleton|microtubule cytoskeleton|membrane|axon|growth cone|cell leading edge|motile primary cilium|vesicle|neuron projection|neuronal cell body|perinuclear region of cytoplasm|extracellular vesicular exosome|,establishment of mitotic spindle orientation|microtubule cytoskeleton organization|microtubule cytoskeleton organization|ameboidal cell migration|acrosome assembly|neuron migration|neuron migration|neuron migration|positive regulation of cytokine-mediated signaling pathway|lipid metabolic process|transport|microtubule-based process|cell cycle|mitotic nuclear division|nuclear migration|synaptic transmission|multicellular organismal development|nervous system development|neuroblast proliferation|learning or memory|retrograde axon cargo transport|adult locomotory behavior|adult locomotory behavior|protein secretion|negative regulation of neuron projection development|lipid catabolic process|cell migration|stem cell division|transmission of nerve impulse|corpus callosum morphogenesis|hippocampus development|hippocampus development|layer formation in cerebral cortex|cerebral cortex neuron differentiation|cerebral cortex development|cerebral cortex development|cerebral cortex development|actin cytoskeleton organization|cell differentiation|microtubule organizing center organization|regulation of Rho GTPase activity|osteoclast development|positive regulation of axon extension|positive regulation of mitotic cell cycle|negative regulation of JNK cascade|vesicle transport along microtubule|brain morphogenesis|neuromuscular process controlling balance|neuromuscular process controlling balance|nuclear envelope disassembly|cell division|establishment of centrosome localization|,protein binding|microtubule binding|microtubule binding|protein complex binding|protein homodimerization activity|dynein binding|dynein intermediate chain binding|phosphoprotein binding|,8,1.1,12.6,7,0.8,3.41,0.9,14.8,14.8,0.0879,0,0,0.5,1.7
ENSMUSG00000029649,POMP,proteasome maturation protein,proteasome complex|nucleus|nucleus|cytoplasm|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,proteasome assembly|,protein binding|,7,1.9,10.7,6,1.5,4.84,1.8,14.7,14.7,0.0884,0,0,1.3,2.9
ENSMUSG00000021103,MNAT1,menage a trois 1,nucleus|holo TFIIH complex|cytoplasm|,"G1/S transition of mitotic cell cycle|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein phosphorylation|cell cycle|adult heart development|ventricular system development|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle cell proliferation|response to calcium ion|",protein binding|DNA-dependent ATPase activity|zinc ion binding|RNA polymerase II carboxy-terminal domain kinase activity|metal ion binding|protein N-terminus binding|,10,1,9.1,9,0.8,6.22,0.9,14.6,14.6,0.0888,0,0,0.4,1.5
ENSMUSG00000038379,TTK,Ttk protein kinase,membrane|,protein phosphorylation|mitotic cell cycle checkpoint|phosphorylation|chromosome separation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",7,1.6,13.3,6,1.1,2.37,1.5,14.5,14.5,0.0893,0,0,0.9,2.8
ENSMUSG00000002068,CCNE1,cyclin E1,cyclin-dependent protein kinase holoenzyme complex|nucleus|nucleus|cytoplasm|centrosome|,regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|DNA replication initiation|protein phosphorylation|protein phosphorylation|cell cycle|Wnt signaling pathway|positive regulation of cell differentiation|regulation of protein kinase activity|cell division|regulation of cell cycle|,protein binding|kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|protein kinase binding|protein kinase binding|protein complex binding|,10,-1.1,6.55,10,-1.3,8.53,-1.2,14.5,-14.5,0.0893,0,0,-1.9,-0.4
ENSMUSG00000030612,MRPL46,mitochondrial ribosomal protein L46,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,hydrolase activity|,10,-0.3,3.3,10,1.7,13,1.1,14.4,14.4,0.0897,0,0,0.8,2.5
ENSMUSG00000021156,ZMYND11,"zinc finger, MYND domain containing 11",nucleus|chromosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|regulation of transcription elongation from RNA polymerase II promoter|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of JNK cascade|negative regulation of extrinsic apoptotic signaling pathway|",DNA binding|transcription corepressor activity|zinc ion binding|methylated histone binding|histone binding|metal ion binding|,10,-1,13.7,10,-0.5,1.64,-0.9,14.4,-14.4,0.0897,0,0,-1.6,-0.4
ENSMUSG00000021693,KIF2A,kinesin family member 2A,spindle pole|cytoplasm|lysosome|centrosome|cytoskeleton|kinesin complex|microtubule|spindle microtubule|membrane|,microtubule-based movement|cell cycle|mitotic spindle organization|mitotic nuclear division|multicellular organismal development|nervous system development|cell differentiation|cell division|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,10,1.1,9.49,10,0.6,6.6,0.8,14.3,14.3,0.0902,0,0,0.4,1.6
ENSMUSG00000031311,NONO,"non-POU-domain-containing, octamer binding protein",nucleus|nucleus|membrane|nuclear matrix|paraspeckles|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|cellular response to DNA damage stimulus|circadian rhythm|RNA splicing|regulation of circadian rhythm|negative regulation of transcription, DNA-templated|rhythmic process|",nucleotide binding|core promoter binding|nucleic acid binding|DNA binding|RNA binding|protein binding|identical protein binding|poly(A) RNA binding|,10,0.8,11.6,10,0.8,3.04,0.8,14.3,14.3,0.0902,0,0,0.4,1.5
ENSMUSG00000041238,RBBP8,retinoblastoma binding protein 8,nucleus|transcriptional repressor complex|,"G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|double-strand break repair via homologous recombination|DNA catabolic process, endonucleolytic|blastocyst hatching|DNA repair|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|meiotic nuclear division|DNA double-strand break processing involved in repair via single-strand annealing|G2 DNA damage checkpoint|cell division|",single-stranded DNA endodeoxyribonuclease activity|RNA polymerase II repressing transcription factor binding|RNA polymerase II transcription corepressor activity|DNA binding|damaged DNA binding|nuclease activity|endonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,0.9,7.49,10,0.9,6.98,0.9,14.1,14.1,0.0914,0,0,0.5,1.6
ENSMUSG00000021287,XRCC3,X-ray repair complementing defective repair in Chinese hamster cells 3,nucleus|replication fork|cytoplasm|mitochondrion|Rad51C-XRCC3 complex|perinuclear region of cytoplasm|,"double-strand break repair via homologous recombination|DNA catabolic process, endonucleolytic|DNA metabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|regulation of centrosome duplication|resolution of mitotic recombination intermediates|positive regulation of mitotic cell cycle spindle assembly checkpoint|",nucleotide binding|four-way junction DNA binding|DNA binding|ATP binding|DNA-dependent ATPase activity|crossover junction endodeoxyribonuclease activity|,8,0.7,7.82,7,1.7,10.3,1,14.1,14.1,0.0914,0,0,0.4,2.5
ENSMUSG00000033307,MIF,macrophage migration inhibitory factor,extracellular region|extracellular space|extracellular space|intracellular|nucleus|cytoplasm|cell surface|extracellular vesicular exosome|,"prostaglandin biosynthetic process|positive regulation of protein phosphorylation|brain renin-angiotensin system|immune system process|positive regulation of acute inflammatory response|positive regulation of adaptive immune response|negative regulation of mature B cell apoptotic process|inflammatory response|cell surface receptor signaling pathway|spermatogenesis|cell aging|cell proliferation|negative regulation of gene expression|positive regulation of protein kinase A signaling|positive regulation of smooth muscle cell migration|carboxylic acid metabolic process|DNA damage response, signal transduction by p53 class mediator|positive regulation of B cell proliferation|positive regulation of lipopolysaccharide-mediated signaling pathway|negative regulation of cellular protein metabolic process|negative regulation of myeloid cell apoptotic process|positive regulation of peptidyl-serine phosphorylation|positive regulation of peptidyl-serine phosphorylation|regulation of cell proliferation|positive regulation of phosphorylation|drinking behavior|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of potassium ion transport|positive regulation of MAP kinase activity|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of DNA damage response, signal transduction by p53 class mediator|innate immune response|positive regulation of glycolytic process|positive regulation of glucose import|positive regulation of fibroblast proliferation|positive regulation of fibroblast proliferation|positive regulation of axon regeneration|positive regulation of cytokine secretion|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of immune response|positive chemotaxis|positive regulation of prostaglandin secretion involved in immune response|positive regulation of myeloid leukocyte cytokine production involved in immune response|protein homotrimerization|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|negative regulation of cell cycle arrest|positive regulation of arachidonic acid secretion|negative regulation of cell aging|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of chemokine (C-X-C motif) ligand 2 production|",dopachrome isomerase activity|receptor binding|cytokine activity|cytokine activity|cytokine receptor binding|isomerase activity|protein complex binding|chemoattractant activity|phenylpyruvate tautomerase activity|phenylpyruvate tautomerase activity|,10,-1,7.31,10,-0.9,7.17,-0.9,14.1,-14.1,0.0914,0,0,-1.6,-0.5
ENSMUSG00000032126,HMBS,hydroxymethylbilane synthase,condensed chromosome|nucleus|cytoplasm|axon|,porphyrin-containing compound biosynthetic process|heme biosynthetic process|peptidyl-pyrromethane cofactor linkage|tetrapyrrole biosynthetic process|,hydroxymethylbilane synthase activity|uroporphyrinogen-III synthase activity|transferase activity|carboxylic acid binding|amine binding|coenzyme binding|,10,-0.6,7.26,10,-0.5,7.24,-0.6,14.1,-14.1,0.0914,0,0,-1.1,-0.3
ENSMUSG00000025465,ECHS1,"enoyl Coenzyme A hydratase, short chain, 1, mitochondrial",mitochondrion|mitochondrion|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|metabolic process|,catalytic activity|enoyl-CoA hydratase activity|lyase activity|,10,-1.1,9.1,10,-0.5,6.02,-0.5,13.8,-13.8,0.0929,0,0,-1.4,-0.3
ENSMUSG00000029313,AFF1,"AF4/FMR2 family, member 1",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|,10,-0.3,0.0895,10,-1.6,16.4,-1.6,13.7,-13.7,0.0936,0,0,-3,-0.6
ENSMUSG00000043866,TAF10,"TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor",PCAF complex|nucleus|nucleus|transcription factor TFIID complex|transcription factor TFIID complex|cytoplasm|STAGA complex|transcription factor TFTC complex|perinuclear region of cytoplasm|,"G1/S transition of mitotic cell cycle|liver development|transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|apoptotic process|embryo development|regulation of gene expression|histone deubiquitination|multicellular organism growth|cellular protein complex assembly|histone H3 acetylation|regulation of DNA binding|protein homooligomerization|hepatocyte differentiation|regulation of RNA biosynthetic process|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|histone acetyltransferase activity|enzyme binding|estrogen receptor binding|RNA polymerase binding|,10,0.7,9.9,10,0.7,4.21,0.7,13.7,13.7,0.0936,0,0,0.4,1.3
ENSMUSG00000026234,NCL,nucleolin,nucleus|nucleus|nucleoplasm|nucleolus|nucleolus|cytoplasm|cell cortex|membrane|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|extracellular vesicular exosome|,angiogenesis|positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|,nucleotide binding|nucleic acid binding|DNA binding|RNA binding|RNA binding|protein binding|protein C-terminus binding|telomeric DNA binding|identical protein binding|poly(A) RNA binding|,6,1.2,14,6,-0.9,5.07,1.1,13.6,13.6,0.0941,0,0,0.6,2
ENSMUSG00000025616,USP16,ubiquitin specific peptidase 16,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|proteolysis|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|chromatin modification|histone deubiquitination|monoubiquitinated histone H2A deubiquitination|positive regulation of transcription, DNA-templated|positive regulation of translational elongation|positive regulation of transcription from RNA polymerase II promoter|protein homotetramerization|cell division|histone H2A K63-linked deubiquitination|",transcription coactivator activity|cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|histone binding|ubiquitin binding|metal ion binding|,9,0.4,0.801,9,1.3,14.9,1.2,13.5,13.5,0.0948,0,0,0.5,2.2
ENSMUSG00000021022,PPP2R3C,"protein phosphatase 2, regulatory subunit B'', gamma",nucleus|cytoplasm|centrosome|,B cell homeostasis|regulation of antimicrobial humoral response|activation of protein kinase activity|T cell homeostasis|positive regulation of B cell differentiation|spleen development|regulation of B cell activation|regulation of mitochondrial depolarization|,calcium ion binding|protein binding|metal ion binding|,10,0.9,3.48,10,1,10.3,0.9,13.4,13.4,0.0953,0,0,0.4,1.7
ENSMUSG00000070544,TOP1,topoisomerase (DNA) I,nuclear chromosome|cytoplasmic mRNA processing body|fibrillar center|dense fibrillar component|nucleus|nucleus|nucleoplasm|chromosome|nucleolus|nucleolus|cytoplasm|replication fork protection complex|perikaryon|,DNA replication|DNA topological change|DNA topological change|chromatin remodeling|chromosome segregation|rRNA transcription|embryonic cleavage|,DNA binding|chromatin binding|DNA topoisomerase activity|DNA topoisomerase type I activity|DNA topoisomerase type I activity|DNA topoisomerase type II (ATP-hydrolyzing) activity|isomerase activity|chromatin DNA binding|protein complex binding|poly(A) RNA binding|,9,-0.8,12.2,9,-1.6,4.78,-1.2,13.4,-13.4,0.0953,0,0,-2.3,-0.5
ENSMUSG00000027720,IL2,interleukin 2,extracellular region|extracellular space|extracellular space|,negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|immune system process|negative regulation of B cell apoptotic process|immune response|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|protein kinase C-activating G-protein coupled receptor signaling pathway|positive regulation of B cell proliferation|positive regulation of interferon-gamma production|positive regulation of interleukin-17 production|positive regulation of T cell proliferation|positive regulation of T cell proliferation|positive regulation of T cell proliferation|positive regulation of activated T cell proliferation|positive regulation of activated T cell proliferation|positive regulation of activated T cell proliferation|positive regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of T cell differentiation|positive regulation of regulatory T cell differentiation|negative regulation of heart contraction|positive regulation of transcription from RNA polymerase II promoter|regulation of T cell homeostatic proliferation|positive regulation of isotype switching to IgG isotypes|negative regulation of lymphocyte proliferation|negative regulation of inflammatory response|positive regulation of immunoglobulin secretion|positive regulation of dendritic spine development|extrinsic apoptotic signaling pathway in absence of ligand|,cytokine activity|cytokine activity|cytokine activity|interleukin-2 receptor binding|interleukin-2 receptor binding|growth factor activity|carbohydrate binding|kappa-type opioid receptor binding|glycosphingolipid binding|,10,-0.8,13.7,10,-0.3,1.72,-0.7,13.2,-13.2,0.0967,0,0,-1.3,-0.3
ENSMUSG00000040761,SPEN,"SPEN homolog, transcriptional regulator (Drosophila)",nucleus|nucleus|transcriptional repressor complex|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|Notch signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of neurogenesis|",nucleotide binding|RNA polymerase II transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|single-stranded DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|RNA binding|protein binding|poly(A) RNA binding|,10,-0.8,7.44,10,-0.7,6.11,-0.7,13.2,-13.2,0.0967,0,0,-1.5,-0.4
ENSMUSG00000018736,NDEL1,nuclear distribution gene E-like homolog 1 (A. nidulans),"chromosome, centromeric region|kinetochore|nuclear envelope|chromosome|nucleolus|cytoplasm|centrosome|centrosome|microtubule organizing center|cytoskeleton|kinesin complex|microtubule|microtubule associated complex|axon|axon|cell leading edge|axon hillock|cell body|neurofilament cytoskeleton|",microtubule cytoskeleton organization|neuron migration|inner cell mass cell proliferation|proteolysis|transport|chromosome segregation|mitotic centrosome separation|mitotic centrosome separation|multicellular organismal development|nervous system development|retrograde axon cargo transport|regulation of neuron projection development|regulation of neuron projection development|cell migration|cerebral cortex radially oriented cell migration|central nervous system neuron axonogenesis|cell differentiation|neuron projection development|activation of Cdc42 GTPase activity|positive regulation of axon extension|vesicle transport along microtubule|positive regulation of axon regeneration|nuclear envelope disassembly|centrosome localization|neurofilament cytoskeleton organization|neuron projection extension|,protein binding|microtubule binding|protein complex binding|alpha-tubulin binding|beta-tubulin binding|oligopeptidase activity|,10,0.6,4.8,10,0.9,9.74,0.8,13.1,13.1,0.0974,0,0,0.3,1.3
ENSMUSG00000089960,UGT1A1,"UDP glucuronosyltransferase 1 family, polypeptide A1",endoplasmic reticulum|integral component of plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|cytochrome complex|,metabolic process|response to organic substance|negative regulation of catalytic activity|flavone metabolic process|cellular glucuronidation|flavonoid glucuronidation|xenobiotic glucuronidation|biphenyl catabolic process|negative regulation of cellular glucuronidation|,"retinoic acid binding|enzyme inhibitor activity|steroid binding|glucuronosyltransferase activity|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|enzyme binding|protein homodimerization activity|protein heterodimerization activity|",5,0.6,1.63,5,1.4,13.1,1.3,13.1,13.1,0.0974,0,0,0.7,2.8
ENSMUSG00000020697,LIG3,"ligase III, DNA, ATP-dependent",condensed nuclear chromosome|synaptonemal complex|nucleus|nucleus|chromosome|mitochondrion|,"DNA replication|DNA ligation|lagging strand elongation|DNA repair|base-excision repair, DNA ligation|nucleotide-excision repair|double-strand break repair via nonhomologous end joining|DNA recombination|cellular response to DNA damage stimulus|cell cycle|mitochondrial DNA repair|negative regulation of DNA recombination|DNA ligation involved in DNA repair|cell division|DNA biosynthetic process|",nucleotide binding|DNA binding|DNA ligase activity|DNA ligase (ATP) activity|protein binding|ATP binding|zinc ion binding|ligase activity|metal ion binding|,9,1.2,9.35,9,1.3,4.2,1.2,13.1,13.1,0.0974,0,0,0.5,2.3
ENSMUSG00000005732,RANBP1,RAN binding protein 1,cytoplasm|centrosome|,spindle organization|positive regulation of mitotic centrosome separation|intracellular transport|,GTPase activator activity|,9,-0.9,6.67,8,-1.1,7.11,-0.9,13.1,-13.1,0.0974,0,0,-1.8,-0.5
ENSMUSG00000000126,WNT9A,"wingless-type MMTV integration site family, member 9A",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular vesicular exosome|,mitotic cell cycle checkpoint|multicellular organismal development|negative regulation of cell proliferation|Wnt signaling pathway|neuron differentiation|negative regulation of chondrocyte differentiation|negative regulation of chondrocyte differentiation|embryonic forelimb morphogenesis|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|cell fate commitment|positive regulation of cell differentiation|positive regulation of smoothened signaling pathway|embryonic skeletal system morphogenesis|anatomical structure development|canonical Wnt signaling pathway|negative regulation of cell death|negative regulation of cartilage development|,receptor binding|frizzled binding|protein binding|,10,-1.8,16.3,10,1.3,3.59,-1.8,13,-13,0.0981,0,0,-4,-0.4
ENSMUSG00000028709,MOB3C,MOB kinase activator 3C,cellular_component|,biological_process|phosphorylation|,molecular_function|kinase activity|transferase activity|metal ion binding|,10,-0.5,6.61,10,-0.8,7.99,-0.6,13,-13,0.0981,0,0,-1.2,-0.3
ENSMUSG00000001707,EEF1E1,eukaryotic translation elongation factor 1 epsilon 1,nucleus|cytoplasm|aminoacyl-tRNA synthetase multienzyme complex|extracellular vesicular exosome|,"DNA repair|translation|translational elongation|negative regulation of cell proliferation|embryo development|positive regulation of apoptotic process|positive regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of apoptotic signaling pathway|",translation elongation factor activity|protein binding|,9,-1.2,8.88,9,-0.8,4.63,-1,12.7,-12.7,0.1,0,0,-1.8,-0.6
ENSMUSG00000026162,NHEJ1,nonhomologous end-joining factor 1,nucleus|nucleus|nonhomologous end joining complex|,DNA repair|double-strand break repair|double-strand break repair via nonhomologous end joining|double-strand break repair via nonhomologous end joining|DNA recombination|cellular response to DNA damage stimulus|response to ionizing radiation|response to ionizing radiation|B cell differentiation|B cell differentiation|T cell differentiation|T cell differentiation|,DNA binding|,10,0.9,3.46,10,1,9.66,1,12.7,12.7,0.1,0,0,0.5,1.8
ENSMUSG00000038489,POLR2L,polymerase (RNA) II (DNA directed) polypeptide L,"nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase I complex|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase I activity|RNA polymerase II activity|RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|zinc ion binding|metal ion binding|,4,-0.5,0.855,4,1.5,14.6,1.4,12.6,12.6,0.101,0,0,1,3
ENSMUSG00000025135,ANAPC11,anaphase promoting complex subunit 11,nucleus|anaphase-promoting complex|cytoplasm|,cell cycle|mitotic nuclear division|protein ubiquitination|cell division|protein K11-linked ubiquitination|,ubiquitin-protein transferase activity|zinc ion binding|metal ion binding|,8,-1.3,9.14,8,-0.6,6.56,-0.9,12.6,-12.6,0.101,0,0,-1.9,-0.4
ENSMUSG00000026192,ATIC,5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase,mitochondrion|membrane|extracellular vesicular exosome|,purine nucleotide biosynthetic process|'de novo' IMP biosynthetic process|metabolic process|nucleoside metabolic process|ribonucleotide metabolic process|dihydrofolate metabolic process|tetrahydrofolate biosynthetic process|,catalytic activity|IMP cyclohydrolase activity|phosphoribosylaminoimidazolecarboxamide formyltransferase activity|transferase activity|hydrolase activity|protein homodimerization activity|,6,0.9,7.28,6,1,5.62,0.9,12.4,12.4,0.103,0,0,0.5,1.9
ENSMUSG00000040731,EIF4H,eukaryotic translation initiation factor 4H,cytoplasm|membrane|,translation|translational initiation|sexual reproduction|developmental growth|,nucleotide binding|nucleic acid binding|RNA binding|translation initiation factor activity|poly(A) RNA binding|,10,0.7,1.92,10,0.9,10.9,0.8,12.3,12.3,0.104,0,0,0.3,1.5
ENSMUSG00000007836,HNRNPA0,heterogeneous nuclear ribonucleoprotein A0,nucleus|ribonucleoprotein complex|,inflammatory response|response to lipopolysaccharide|3'-UTR-mediated mRNA stabilization|,nucleotide binding|nucleic acid binding|RNA binding|AU-rich element binding|AU-rich element binding|protein kinase binding|poly(A) RNA binding|,10,0.5,2.81,10,1.2,12.5,1,12.1,12.1,0.105,0,0,0.4,1.8
ENSMUSG00000058290,ESPL1,extra spindle pole bodies 1 (S. cerevisiae),nucleus|cytoplasm|centrosome|,mitotic sister chromatid segregation|mitotic sister chromatid segregation|meiotic spindle organization|proteolysis|chromosome segregation|mitotic nuclear division|meiosis I|homologous chromosome segregation|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,7,1.7,13.6,6,0.4,0.296,1.5,12,12,0.106,0,0,1,2.8
ENSMUSG00000029191,RFC1,replication factor C (activator 1) 1,nucleus|nucleus|DNA replication factor C complex|nucleolus|cytoplasm|Golgi apparatus|cell junction|protein complex|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",nucleotide binding|DNA binding|DNA clamp loader activity|double-stranded DNA binding|ATP binding|protein domain specific binding|sequence-specific DNA binding|,9,0.8,5.39,10,1.2,7.4,0.8,12,12,0.106,0,0,0.4,1.7
ENSMUSG00000015721,NLRP5,"NLR family, pyrin domain containing 5",nucleus|nucleolus|cytoplasm|mitochondrion|cytosol|cell cortex|protein complex|apical cortex|,in utero embryonic development|embryo implantation|fertilization|organ morphogenesis|regulation of protein stability|cellular protein localization|regulation of RNA stability|cellular protein complex assembly|neuron death|,nucleotide binding|protein binding|ATP binding|,10,-1.1,10.1,10,-1.1,1.97,-1.1,11.8,-11.8,0.108,0,0,-1.9,-0.7
ENSMUSG00000001674,DDX18,DEAD (Asp-Glu-Ala-Asp) box polypeptide 18,nucleus|nucleolus|membrane|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,7,1.1,7.98,7,1.2,4.11,1.2,11.7,11.7,0.108,0,0,0.6,2
ENSMUSG00000022814,UMPS,uridine monophosphate synthetase,nucleus|cytoplasm|,'de novo' pyrimidine nucleobase biosynthetic process|pyrimidine nucleotide biosynthetic process|UMP biosynthetic process|metabolic process|nucleoside metabolic process|'de novo' UMP biosynthetic process|,"catalytic activity|orotate phosphoribosyltransferase activity|orotidine-5'-phosphate decarboxylase activity|transferase activity|transferase activity, transferring glycosyl groups|lyase activity|carboxy-lyase activity|",10,0.8,9.91,8,0.8,2.11,0.8,11.7,11.7,0.108,0,0,0.4,1.6
ENSMUSG00000087260,LAMTOR5,"late endosomal/lysosomal adaptor, MAPK and MTOR activator 5",cytoplasm|lysosome|cytosol|Ragulator complex|,regulation of cell size|viral genome replication|positive regulation of TOR signaling|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of GTPase activity|protein localization to lysosome|cellular response to amino acid stimulus|,guanyl-nucleotide exchange factor activity|protein complex scaffold|,9,0.1,0.0547,9,2,14.7,1.9,11.7,11.7,0.108,0,0,1,3.6
ENSMUSG00000019179,MDH2,"malate dehydrogenase 2, NAD (mitochondrial)",nucleus|mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|plasma membrane|extracellular vesicular exosome|,carbohydrate metabolic process|tricarboxylic acid cycle|oxaloacetate metabolic process|malate metabolic process|malate metabolic process|internal protein amino acid acetylation|NADH metabolic process|cellular carbohydrate metabolic process|oxidation-reduction process|,"catalytic activity|oxidoreductase activity|malate dehydrogenase activity|malate dehydrogenase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|L-malate dehydrogenase activity|L-malate dehydrogenase activity|protein self-association|poly(A) RNA binding|malate dehydrogenase (NADP+) activity|",9,-0.6,8.22,9,-0.5,4.01,-0.5,11.7,-11.7,0.108,0,0,-1.1,-0.2
ENSMUSG00000021385,IPPK,"inositol 1,3,4,5,6-pentakisphosphate 2-kinase",intracellular|nucleus|cytoplasm|,phosphorylation|inositol phosphorylation|,nucleotide binding|ATP binding|kinase activity|transferase activity|inositol pentakisphosphate 2-kinase activity|,8,0.9,11.3,8,0.4,1.66,0.8,11.6,11.6,0.109,0,0,0.4,1.7
ENSMUSG00000023932,CDC5L,cell division cycle 5-like (S. pombe),Prp19 complex|nucleus|spliceosomal complex|cytoplasm|membrane|nuclear speck|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|cell cycle|RNA splicing|",DNA binding|chromatin binding|RNA binding|protein domain specific binding|poly(A) RNA binding|WD40-repeat domain binding|,7,1.1,14.1,7,0,0,1.1,11.6,11.6,0.109,0,0,0.4,1.9
ENSMUSG00000035960,APEX1,apurinic/apyrimidinic endonuclease 1,intracellular|nucleus|nucleus|nucleoplasm|transcription factor complex|nucleolus|cytoplasm|cytoplasm|mitochondrion|endoplasmic reticulum|centrosome|nuclear speck|perinuclear region of cytoplasm|,"DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|DNA catabolic process, exonucleolytic|DNA repair|base-excision repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|aging|negative regulation of smooth muscle cell migration|regulation of mRNA stability|cell redox homeostasis|positive regulation of DNA repair|oxidation-reduction process|cellular response to hydrogen peroxide|DNA demethylation|nucleic acid phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, endonucleolytic|positive regulation of G1/S transition of mitotic cell cycle|regulation of RNA biosynthetic process|","DNA binding|damaged DNA binding|transcription coactivator activity|RNA binding|DNA-(apurinic or apyrimidinic site) lyase activity|DNA-(apurinic or apyrimidinic site) lyase activity|nuclease activity|endonuclease activity|endoribonuclease activity|exonuclease activity|double-stranded DNA 3'-5' exodeoxyribonuclease activity|3'-5' exonuclease activity|oxidoreductase activity|hydrolase activity|lyase activity|site-specific endodeoxyribonuclease activity, specific for altered base|chromatin DNA binding|protein complex binding|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|poly(A) RNA binding|retroviral 3' processing activity|metal ion binding|NF-kappaB binding|",9,0,0,9,1.7,14.6,1.7,11.5,11.5,0.11,0,0,0.9,3
ENSMUSG00000020361,HSPA4,heat shock protein 4,nucleus|cytoplasm|mitochondrion|lipid particle|cytosol|extracellular vesicular exosome|,negative regulation of protein phosphorylation|response to stress|response to heat|positive regulation of gene expression|negative regulation of gene expression|positive regulation of protein binding|negative regulation of apoptotic process|negative regulation of DNA binding|protein import into mitochondrial outer membrane|chaperone-mediated protein complex assembly|negative regulation of cell death|,nucleotide binding|RNA polymerase II transcription factor binding|protein binding|ATP binding|protein complex binding|activating transcription factor binding|,9,0.7,1.38,9,1,10.8,0.9,11.4,11.4,0.111,0,0,0.4,1.7
ENSMUSG00000018168,IKZF3,IKAROS family zinc finger 3,nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of B cell proliferation|B cell activation|regulation of apoptotic process|regulation of B cell differentiation|regulation of lymphocyte differentiation|",nucleic acid binding|DNA binding|protein binding|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|protein heterodimerization activity|,10,2.2,14.6,10,0.2,0.316,2.2,11.4,11.4,0.111,0,0,0.4,4
ENSMUSG00000060743,H3F3A,"H3 histone, family 3A",nuclear chromosome|nuclear nucleosome|Barr body|nucleus|protein complex|extracellular vesicular exosome|,osteoblast differentiation|muscle cell differentiation|negative regulation of chromosome condensation|,RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|nucleosomal DNA binding|,6,-1.3,13.6,8,-0.2,0.573,-1.3,11.4,-11.4,0.111,0,0,-2.5,-0.5
ENSMUSG00000029556,HNF1A,HNF1 homeobox A,photoreceptor outer segment|cell|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|protein complex|pronucleus|,"negative regulation of transcription from RNA polymerase II promoter|blastocyst development|liver development|placenta development|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|fatty acid biosynthetic process|bile acid biosynthetic process|heme biosynthetic process|response to oxidative stress|protein localization|cholesterol metabolic process|response to glucose|bile acid and bile salt transport|fatty acid transport|insulin secretion|insulin secretion|regulation of Wnt signaling pathway|embryonic limb morphogenesis|endocrine pancreas development|renal glucose absorption|renal glucose absorption|glucose homeostasis|glucose homeostasis|glucose homeostasis|reverse cholesterol transport|bone resorption|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|glucose import|glucose import|regulation of hormone secretion|paraxial mesoderm formation|reproductive structure development|regulation of insulin secretion|positive regulation of transcription initiation from RNA polymerase II promoter|SMAD protein signal transduction|",RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|transcription cofactor binding|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein homodimerization activity|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|protein dimerization activity|,10,0.9,7.61,10,0.7,4.23,0.9,11.4,11.4,0.111,0,0,0.3,1.6
ENSMUSG00000009905,KDSR,3-ketodihydrosphingosine reductase,endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|3-keto-sphinganine metabolic process|metabolic process|sphingolipid biosynthetic process|oxidation-reduction process|,oxidoreductase activity|3-dehydrosphinganine reductase activity|,9,0.8,9.24,9,1.1,2.71,1,11.3,11.3,0.112,0,0,0.4,1.7
ENSMUSG00000066306,NUMA1,nuclear mitotic apparatus protein 1,spindle pole|cell|nucleus|cytoplasm|spindle microtubule|nuclear matrix|dendrite|neuronal cell body|apical part of cell|,establishment of mitotic spindle orientation|lung epithelial cell differentiation|,microtubule binding|tubulin binding|,10,1,5.89,9,1.1,5.75,1,11.2,11.2,0.113,0,0,0.4,1.8
ENSMUSG00000029730,MCM7,minichromosome maintenance deficient 7 (S. cerevisiae),nucleus|nucleus|cytoplasm|cytosol|membrane|MCM complex|,DNA replication|DNA unwinding involved in DNA replication|DNA replication initiation|cellular response to DNA damage stimulus|cell cycle|cell proliferation|regulation of phosphorylation|,nucleotide binding|DNA binding|DNA helicase activity|single-stranded DNA binding|ATP-dependent DNA helicase activity|helicase activity|protein binding|ATP binding|hydrolase activity|,8,-1.1,9.75,6,0.9,10,0.9,11.2,11.2,0.113,0,0,-1.3,2
ENSMUSG00000052253,ZFP622,zinc finger protein 622,nucleus|nucleolus|cytoplasm|Golgi apparatus|,intrinsic apoptotic signaling pathway in response to oxidative stress|positive regulation of kinase activity|positive regulation of apoptotic process|positive regulation of MAPK cascade|positive regulation of JNK cascade|,nucleic acid binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0.6,5.81,10,1.9,10.9,1.8,11.1,11.1,0.114,0,0,0.8,3.4
ENSMUSG00000031453,RASA3,RAS p21 protein activator 3,intracellular|cytoplasm|intrinsic component of the cytoplasmic side of the plasma membrane|intrinsic component of the cytoplasmic side of the plasma membrane|,signal transduction|positive regulation of Ras GTPase activity|intracellular signal transduction|negative regulation of Ras protein signal transduction|regulation of small GTPase mediated signal transduction|calcium ion transmembrane transport|,GTPase activator activity|Ras GTPase activator activity|calcium-release channel activity|metal ion binding|,9,-0.1,0.388,9,2.4,14.4,2.4,11.1,11.1,0.114,0,0,1.3,4
ENSMUSG00000055491,PPRC1,"peroxisome proliferative activated receptor, gamma, coactivator-related 1",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.6,4,10,0.5,7.59,0.5,11,11,0.116,0,0,0.2,1.3
ENSMUSG00000070691,RUNX3,runt related transcription factor 3,nuclear chromatin|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|chondrocyte differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|axon guidance|hair follicle morphogenesis|neuron projection development|interferon-gamma production|mRNA transcription from RNA polymerase II promoter|negative regulation of cell cycle|cell maturation|negative regulation of epithelial cell proliferation|positive regulation of extrinsic apoptotic signaling pathway|",RNA polymerase II regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|ATP binding|,10,-0.4,3.38,10,-0.6,8.08,-0.6,10.9,-10.9,0.117,0,0,-1.1,-0.2
ENSMUSG00000021109,HIF1A,"hypoxia inducible factor 1, alpha subunit",nucleus|nucleus|transcription factor complex|nucleolus|cytoplasm|cytosol|motile cilium|,"angiogenesis|blood vessel development|response to hypoxia|response to hypoxia|response to hypoxia|response to hypoxia|neural crest cell migration|epithelial to mesenchymal transition|embryonic placenta development|embryonic placenta development|B-1 B cell homeostasis|vasculature development|heart looping|positive regulation of neuroblast proliferation|connective tissue replacement involved in inflammatory response wound healing|outflow tract morphogenesis|cardiac ventricle morphogenesis|lactate metabolic process|regulation of glycolytic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cellular iron ion homeostasis|signal transduction|lactation|positive regulation of cell proliferation|visual learning|regulation of gene expression|vascular endothelial growth factor production|positive regulation vascular endothelial growth factor production|positive regulation of epithelial cell migration|positive regulation of receptor biosynthetic process|response to muscle activity|axon transport of mitochondrion|neural fold elevation formation|cerebral cortex development|cell differentiation|cell differentiation|negative regulation of bone mineralization|positive regulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of TOR signaling|oxygen homeostasis|oxygen homeostasis|regulation of transforming growth factor beta2 production|collagen metabolic process|negative regulation of transcription elongation from RNA polymerase II promoter|embryonic hemopoiesis|positive regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of cell proliferation|hemoglobin biosynthetic process|glucose homeostasis|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|positive regulation of erythrocyte differentiation|positive regulation of transcription, DNA-templated|negative regulation of vasoconstriction|negative regulation of growth|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|muscle cell cellular homeostasis|positive regulation of hormone biosynthetic process|blood vessel morphogenesis|digestive tract morphogenesis|positive regulation of smooth muscle cell proliferation|regulation of catalytic activity|cartilage development|elastin metabolic process|intestinal epithelial cell maturation|epithelial cell differentiation involved in mammary gland alveolus development|retina vasculature development in camera-type eye|positive regulation of transcription from RNA polymerase II promoter in response to hypoxia|regulation of thymocyte apoptotic process|negative regulation of thymocyte apoptotic process|cellular response to hypoxia|cellular response to hypoxia|dopaminergic neuron differentiation|dopaminergic neuron differentiation|negative regulation of mesenchymal cell apoptotic process|",transcription factor binding transcription factor activity|RNA polymerase II transcription factor binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|signal transducer activity|protein binding|transcription factor binding|enzyme binding|protein kinase binding|ubiquitin protein ligase binding|protein complex binding|histone acetyltransferase binding|nuclear hormone receptor binding|histone deacetylase binding|sequence-specific DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|Hsp90 protein binding|,10,0.8,9.01,10,0.6,2.49,0.7,10.9,10.9,0.117,0,0,0.3,1.3
ENSMUSG00000025220,MGEA5,meningioma expressed antigen 5 (hyaluronidase),nucleus|cytoplasm|mitochondrion|membrane|,N-acetylglucosamine metabolic process|protein targeting to membrane|metabolic process|positive regulation of calcium ion transport into cytosol|negative regulation of cardiac muscle adaptation|histone acetylation|positive regulation of cell killing|positive regulation of insulin secretion|positive regulation of protein complex disassembly|positive regulation of proteolysis|dATP metabolic process|positive regulation of glucose import|positive regulation of DNA metabolic process|positive regulation of mitochondrial depolarization|positive regulation of calcium ion transport|negative regulation of protein glycosylation|positive regulation of growth hormone secretion|necrotic cell death|,"catalytic activity|histone acetyltransferase activity|beta-N-acetylglucosaminidase activity|transferase activity|transferase activity, transferring acyl groups|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.6,5.92,10,0.6,5.34,0.6,10.9,10.9,0.117,0,0,0.2,1.2
ENSMUSG00000022594,LYNX1,Ly6/neurotoxin 1,plasma membrane|membrane|extracellular vesicular exosome|,"synaptic transmission, cholinergic|negative regulation of receptor activity|",protein binding|ion channel inhibitor activity|acetylcholine receptor inhibitor activity|,10,1.1,4.82,10,1.1,6.4,1.1,10.9,10.9,0.117,0,0,0.4,1.9
ENSMUSG00000028443,NUDT2,nudix (nucleoside diphosphate linked moiety X)-type motif 2,mitochondrion|,apoptotic process|,nucleotide binding|bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity|GTP binding|bis(5'-nucleosyl)-tetraphosphatase activity|hydrolase activity|,10,1.3,10.4,10,0.4,4.59,0.7,10.9,10.9,0.117,0,0,0.3,2
ENSMUSG00000030062,RPN1,ribophorin I,endoplasmic reticulum|endoplasmic reticulum membrane|rough endoplasmic reticulum|membrane|membrane|integral component of membrane|,protein glycosylation|protein N-linked glycosylation via asparagine|,"dolichyl-diphosphooligosaccharide-protein glycotransferase activity|transferase activity|transferase activity, transferring glycosyl groups|poly(A) RNA binding|",9,-1.3,12.3,9,1.1,8.07,-1.1,10.9,-10.9,0.117,0,0,-3,1
ENSMUSG00000052429,PRMT1,protein arginine N-methyltransferase 1,nucleus|cytoplasm|cytosol|cytosol|protein complex|,"in utero embryonic development|regulation of transcription, DNA-templated|protein methylation|protein methylation|histone methylation|peptidyl-arginine methylation|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|neuron projection development|methylation|peptidyl-arginine N-methylation|peptidyl-arginine omega-N-methylation|histone H4-R3 methylation|histone H4-R3 methylation|negative regulation of megakaryocyte differentiation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|[cytochrome c]-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|snoRNP binding|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N monomethyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|histone methyltransferase activity|identical protein binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|histone methyltransferase activity (H4-R3 specific)|histone methyltransferase activity (H4-R3 specific)|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",7,1.3,10.8,7,-0.5,2.83,1.2,10.8,10.8,0.118,0,0,0.5,2.7
ENSMUSG00000021957,TKT,transketolase,nucleus|peroxisome|endoplasmic reticulum membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,"pentose-phosphate shunt|metabolic process|pentose-phosphate shunt, non-oxidative branch|regulation of growth|glyceraldehyde-3-phosphate biosynthetic process|ribose phosphate biosynthetic process|",magnesium ion binding|catalytic activity|transketolase activity|transketolase activity|transferase activity|carbohydrate binding|thiamine pyrophosphate binding|protein homodimerization activity|metal ion binding|monosaccharide binding|cofactor binding|,8,0.5,3.3,7,0.6,8.06,0.6,10.8,10.8,0.118,0,0,0.3,1.3
ENSMUSG00000020513,TUBD1,"tubulin, delta 1",nucleus|nucleus|cytoplasm|cytoplasm|cytoskeleton|microtubule|protein complex|,GTP catabolic process|microtubule-based process|multicellular organismal development|spermatogenesis|cell differentiation|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,8,0.9,3.36,9,0.8,7.84,0.9,10.7,10.7,0.119,0,0,0.4,1.6
ENSMUSG00000021635,RAD17,RAD17 homolog (S. pombe),"chromosome, telomeric region|nucleus|",DNA damage checkpoint|DNA repair|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|cell cycle|mitotic cell cycle checkpoint|multicellular organismal development|negative regulation of DNA replication|regulation of phosphorylation|,nucleotide binding|ATP binding|,10,1.2,9.6,8,-0.7,3.53,1.1,10.7,10.7,0.119,0,0,0.3,2.5
ENSMUSG00000034168,IRF2BPL,interferon regulatory factor 2 binding protein-like,extracellular space|nucleus|,negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|development of secondary female sexual characteristics|,molecular_function|metal ion binding|,10,-0.3,3.83,10,-0.6,7.82,-0.5,10.6,-10.6,0.12,0,0,-1,-0.2
ENSMUSG00000059439,BCAS3,breast carcinoma amplified sequence 3,nucleus|cytoplasm|cell periphery|,None,None,10,1.4,7.95,10,0.7,5.23,0.9,10.6,10.6,0.12,0,0,0.5,2.2
ENSMUSG00000005779,PSMB4,"proteasome (prosome, macropain) subunit, beta type 4",proteasome complex|nucleus|cytoplasm|proteasome core complex|extracellular vesicular exosome|,negative regulation of inflammatory response to antigenic stimulus|proteolysis|proteolysis involved in cellular protein catabolic process|,lipopolysaccharide binding|endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,5,-1.6,12,6,0.9,1.51,-1.5,10.5,-10.5,0.121,0,0,-3,-0.8
ENSMUSG00000052684,JUN,jun proto-oncogene,nuclear chromatin|nucleus|nucleus|transcription factor complex|transcription factor complex|nuclear euchromatin|cytosol|transcriptional repressor complex|,"angiogenesis|angiogenesis|microglial cell activation|release of cytochrome c from mitochondria|liver development|positive regulation of endothelial cell proliferation|outflow tract morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transforming growth factor beta receptor signaling pathway|SMAD protein import into nucleus|learning|positive regulation of cell proliferation|negative regulation of cell proliferation|response to radiation|cellular process|monocyte differentiation|axon regeneration|negative regulation of protein autophosphorylation|positive regulation of Rho GTPase activity|leading edge cell differentiation|response to drug|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of DNA binding|negative regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|negative regulation by host of viral transcription|positive regulation by host of viral transcription|positive regulation of monocyte differentiation|positive regulation of DNA replication|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fibroblast proliferation|positive regulation of fibroblast proliferation|positive regulation of smooth muscle cell proliferation|cellular response to potassium ion starvation|regulation of cell cycle|membrane depolarization|SMAD protein signal transduction|cellular response to calcium ion|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II activating transcription factor binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription coactivator activity|Rho GTPase activator activity|protein binding|transcription factor binding|enzyme binding|cAMP response element binding|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|poly(A) RNA binding|protein heterodimerization activity|R-SMAD binding|HMG box domain binding|,9,-1.4,5.04,8,1.3,13,1.2,10.4,10.4,0.123,0,0,0.5,2
ENSMUSG00000044485,KLK1B11,kallikrein 1-related peptidase b11,nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-1,2.74,10,-1.7,9.49,-1.6,10.3,-10.3,0.124,0,0,-3,-0.7
ENSMUSG00000021210,AKR1C6,"aldo-keto reductase family 1, member C6",nucleus|cytoplasm|,lipid metabolic process|steroid biosynthetic process|steroid metabolic process|response to drug|response to estrogen|daunorubicin metabolic process|doxorubicin metabolic process|oxidation-reduction process|cellular response to jasmonic acid stimulus|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|retinal dehydrogenase activity|aldo-keto reductase (NADP) activity|estradiol 17-beta-dehydrogenase activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity|androsterone dehydrogenase activity|testosterone 17-beta-dehydrogenase (NADP+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,-1,2.09,10,1.7,13,1.7,10.3,10.3,0.124,0,0,0.9,3
ENSMUSG00000054387,MDM4,transformed mouse 3T3 cell double minute 4,nucleus|,negative regulation of transcription from RNA polymerase II promoter|protein complex assembly|positive regulation of cell proliferation|negative regulation of protein catabolic process|negative regulation of apoptotic process|negative regulation of cell cycle arrest|,protein binding|zinc ion binding|enzyme binding|metal ion binding|,8,1.4,2.17,9,1.5,8.47,1.6,10.3,10.3,0.124,0,0,0.8,2.9
ENSMUSG00000045693,NLRP4E,"NLR family, pyrin domain containing 4E",extracellular vesicular exosome|,inflammatory response|biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,-1.8,13.7,-1.7,10.3,-10.3,0.124,0,0,-3,-0.4
ENSMUSG00000031575,ASH2L,"ash2 (absent, small, or homeotic)-like (Drosophila)",nucleus|histone methyltransferase complex|Set1C/COMPASS complex|MLL1 complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|positive regulation of cell proliferation|chromatin modification|response to estrogen|positive regulation of transcription from RNA polymerase II promoter|histone H3-K4 methylation|",DNA binding|protein binding|histone methyltransferase activity (H3-K4 specific)|transcription regulatory region DNA binding|metal ion binding|,8,0.3,0.702,9,0.9,11.1,0.8,10.2,10.2,0.125,0,0,0.3,1.7
ENSMUSG00000063179,PSTK,phosphoseryl-tRNA kinase,mitochondrion|,selenocysteine incorporation|translation|phosphorylation|,tRNA binding|nucleotide binding|ATP binding|kinase activity|transferase activity|,10,0.5,2.93,9,0.6,7.59,0.5,10.1,10.1,0.126,0,0,0.2,1.5
ENSMUSG00000035726,SUPT16,suppressor of Ty 16,nucleus|chromosome|,"DNA replication|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|",poly(A) RNA binding|,3,-0.5,1.22,4,1.3,10.9,1.2,10,10,0.127,0,0,0.6,2
ENSMUSG00000072082,CCNF,cyclin F,nucleus|cytoplasm|centriole|cytoskeleton|SCF ubiquitin ligase complex|,re-entry into mitotic cell cycle|placenta development|cell cycle|mitotic nuclear division|negative regulation of centrosome duplication|protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cell division|regulation of cell cycle|,None,10,1,12.4,10,-0.9,0.652,0.9,9.98,9.98,0.128,0,0,0.4,1.9
ENSMUSG00000064284,CDPF1,"cysteine rich, DPF motif domain containing 1",cellular_component|,biological_process|,molecular_function|,10,0.8,6.47,10,0.8,3.75,0.8,9.86,9.86,0.129,0,0,0.3,1.5
ENSMUSG00000026113,INPP4A,"inositol polyphosphate-4-phosphatase, type I",None,polyphosphate catabolic process|dephosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|,"phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity|hydrolase activity|phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity|",10,0.9,7.68,10,0.4,3.61,0.5,9.79,9.79,0.131,0,0,0.2,1.3
ENSMUSG00000039176,POLG,"polymerase (DNA directed), gamma",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|gamma DNA polymerase complex|mitochondrial nucleoid|extracellular vesicular exosome|,DNA replication|DNA-dependent DNA replication|mitochondrial DNA replication|aging|DNA biosynthetic process|nucleic acid phosphodiester bond hydrolysis|,protease binding|nucleic acid binding|DNA binding|chromatin binding|DNA-directed DNA polymerase activity|exonuclease activity|protein binding|transferase activity|nucleotidyltransferase activity|,10,0.5,2.48,10,1.3,10.1,1.2,9.74,9.74,0.131,0,0,0.3,2.3
ENSMUSG00000028484,PSIP1,PC4 and SFRS1 interacting protein 1,nucleus|nucleoplasm|nuclear heterochromatin|nuclear periphery|transcriptionally active chromatin|,"mRNA 5'-splice site recognition|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to oxidative stress|response to heat|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription coactivator activity|DNA binding|chromatin binding|activating transcription factor binding|poly(A) RNA binding|supercoiled DNA binding|,10,-0.3,2.74,10,-0.7,7.9,-0.6,9.74,-9.74,0.131,0,0,-1.2,-0.2
ENSMUSG00000000355,MCTS1,malignant T cell amplified sequence 1,cytoplasm|plasma membrane|cytosolic small ribosomal subunit|,"formation of translation preinitiation complex|IRES-dependent translational initiation|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle|ribosome disassembly|regulation of growth|",RNA binding|,7,0.9,5.56,6,1.3,5.1,1.2,9.73,9.73,0.131,0,0,0.5,2
ENSMUSG00000024542,CEP192,centrosomal protein 192,pericentriolar material|cytoplasm|cytoplasm|centrosome|centrosome|centriole|,microtubule nucleation|mitotic spindle assembly checkpoint|negative regulation of phosphatase activity|regulation of centriole replication|regulation of centrosome cycle|spindle assembly|centrosome duplication|regulation of establishment of protein localization|,phosphatase binding|,10,1.4,1.01,10,1.5,9.01,1.5,9.7,9.7,0.132,0,0,0.8,2.8
ENSMUSG00000028884,RPA2,replication protein A2,"chromosome, telomeric region|nucleus|DNA replication factor A complex|PML body|PML body|site of double-strand break|",telomere maintenance|double-strand break repair via homologous recombination|DNA replication|DNA repair|base-excision repair|nucleotide-excision repair|mismatch repair|DNA recombination|cellular response to DNA damage stimulus|regulation of double-strand break repair via homologous recombination|mitotic G1 DNA damage checkpoint|regulation of DNA damage checkpoint|,DNA binding|damaged DNA binding|single-stranded DNA binding|protein binding|enzyme binding|protein phosphatase binding|ubiquitin protein ligase binding|protein N-terminus binding|,7,1.6,9.99,6,0.6,2.79,1.6,9.68,9.68,0.132,0,0,0.6,2.9
ENSMUSG00000028851,NUDC,nuclear distribution gene C homolog (Aspergillus),nucleus|cytoplasm|Golgi apparatus|cytoskeleton|microtubule|,cell cycle|mitotic nuclear division|nuclear migration|cell division|,protein binding|,9,-0.6,6.89,8,1.1,8.12,0.7,9.65,9.65,0.133,0,0,-0.4,2
ENSMUSG00000025001,HELLS,"helicase, lymphoid specific","chromosome, centromeric region|nucleus|centromeric heterochromatin|","urogenital system development|DNA methylation|chromatin silencing|methylation-dependent chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|mitotic nuclear division|multicellular organismal development|maintenance of DNA methylation|lymphocyte differentiation|centromeric heterochromatin assembly|negative regulation of apoptotic process|cell division|negative regulation of intrinsic apoptotic signaling pathway|",nucleotide binding|DNA binding|chromatin binding|helicase activity|protein binding|ATP binding|hydrolase activity|,9,0.8,8.62,9,0.6,1.48,0.8,9.57,9.57,0.134,0,0,0.3,1.6
ENSMUSG00000038335,TSR1,TSR1 20S rRNA accumulation,cellular_component|nucleus|,biological_process|ribosome biogenesis|,poly(A) RNA binding|,7,-0.7,0.924,6,1.1,10.4,0.9,9.53,9.53,0.134,0,0,-1.3,2
ENSMUSG00000031666,RBL2,retinoblastoma-like 2,chromatin|nucleus|nucleus|transcription factor complex|nucleolus|cytoplasm|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|cell cycle|chromatin modification|regulation of lipid kinase activity|regulation of cell cycle|",DNA binding|protein binding|,9,-1,7.72,9,-1.1,2.04,-1,9.44,-9.44,0.136,0,0,-2,-0.6
ENSMUSG00000028394,POLE3,"polymerase (DNA directed), epsilon 3 (p17 subunit)",intracellular|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|epsilon DNA polymerase complex|,histone H3 acetylation|,DNA binding|DNA-directed DNA polymerase activity|protein binding|transferase activity|nucleotidyltransferase activity|sequence-specific DNA binding|protein heterodimerization activity|,10,0.6,3.17,9,1.3,6.66,0.7,9.44,9.44,0.136,0,0,0.4,1.8
ENSMUSG00000008348,UBC,ubiquitin C,nucleus|cytoplasm|,ubiquitin homeostasis|,protease binding|protein binding|poly(A) RNA binding|,10,-0.7,8.02,10,-1.2,2.81,-0.7,9.36,-9.36,0.137,0,0,-1.6,-0.2
ENSMUSG00000026187,XRCC5,X-ray repair complementing defective repair in Chinese hamster cells 5,"nuclear chromosome, telomeric region|nucleus|nucleus|chromosome|cytoplasm|cytoplasm|membrane|protein complex|Ku70:Ku80 complex|nonhomologous end joining complex|","telomere maintenance|DNA repair|double-strand break repair|double-strand break repair|double-strand break repair via nonhomologous end joining|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell proliferation|negative regulation of transcription, DNA-templated|positive regulation of neurogenesis|hematopoietic stem cell differentiation|cellular hyperosmotic salinity response|cellular response to X-ray|","nucleotide binding|DNA binding|damaged DNA binding|double-stranded DNA binding|double-stranded telomeric DNA binding|ATP-dependent DNA helicase activity|helicase activity|ATP binding|protein C-terminus binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|ubiquitin protein ligase binding|telomeric DNA binding|transcription regulatory region DNA binding|poly(A) RNA binding|5'-deoxyribose-5-phosphate lyase activity|",10,0.3,2.42,10,1.2,9.81,0.7,9.29,9.29,0.138,0,0,0.3,1.7
ENSMUSG00000038462,UQCRFS1,"ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex III|membrane|integral component of membrane|mitochondrial membrane|respiratory chain|,transport|oxidation-reduction process|,"protein binding|ubiquinol-cytochrome-c reductase activity|oxidoreductase activity|oxidoreductase activity, acting on diphenols and related substances as donors|protein complex binding|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,0.9,5.75,9,1.4,4.55,1,9.25,9.25,0.139,0,0,-0.9,3
ENSMUSG00000032586,TRAIP,TRAF-interacting protein,nucleus|cytoplasm|,signal transduction|signal transduction|protein ubiquitination|intracellular signal transduction|,"ubiquitin-protein transferase activity|receptor signaling protein activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",8,0.4,3.55,7,1.7,9.92,1.6,9.24,9.24,0.139,0,0,0.5,3
ENSMUSG00000003348,MOB3A,MOB kinase activator 3A,intracellular|,biological_process|,molecular_function|metal ion binding|,10,-0.6,4.82,10,-0.5,4.8,-0.5,9.19,-9.19,0.14,0,0,-1.1,-0.2
ENSMUSG00000066828,VMN2R37,"vomeronasal 2, receptor 37",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,9,-1,11.8,9,0.2,0.259,-1,9.19,-9.19,0.14,0,0,-1.8,-0.3
ENSMUSG00000037369,KDM6A,lysine (K)-specific demethylase 6A,nucleus|nucleus|histone methyltransferase complex|histone methyltransferase complex|,in utero embryonic development|neural tube closure|heart morphogenesis|respiratory system process|heart development|regulation of gene expression|chromatin modification|neural tube development|somite rostral/caudal axis specification|multicellular organism growth|mesodermal cell differentiation|embryonic organ development|notochord morphogenesis|oxidation-reduction process|canonical Wnt signaling pathway|histone H3-K27 demethylation|cardiovascular system development|,"sulfonate dioxygenase activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding|protein binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|identical protein binding|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|histone demethylase activity (H3-K27 specific)|",10,1,9.96,10,2,2.35,0.6,9.16,9.16,0.14,0,0,0.2,2.8
ENSMUSG00000036046,5031439G07RIK,RIKEN cDNA 5031439G07 gene,cellular_component|,biological_process|,molecular_function|,10,0.8,1.48,10,1.7,9.47,1.6,9.15,9.15,0.141,0,0,0.5,3
ENSMUSG00000024740,DDB1,damage specific DNA binding protein 1,extracellular space|nucleus|cytoplasm|Cul4A-RING E3 ubiquitin ligase complex|Cul4B-RING E3 ubiquitin ligase complex|extracellular vesicular exosome|Cul4-RING E3 ubiquitin ligase complex|,DNA repair|cellular response to DNA damage stimulus|Wnt signaling pathway|histone H2A monoubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|UV-damage excision repair|regulation of mitotic cell cycle phase transition|,nucleic acid binding|DNA binding|damaged DNA binding|damaged DNA binding|,7,-0.6,3.22,5,-1.1,7.52,-0.9,9.14,-9.14,0.141,0,0,-2,2.4
ENSMUSG00000002949,TIMM44,translocase of inner mitochondrial membrane 44,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial matrix|membrane|,transport|intracellular protein transport|protein transport|,nucleotide binding|ATP binding|P-P-bond-hydrolysis-driven protein transmembrane transporter activity|enzyme binding|chaperone binding|,9,0.8,2.72,9,1.8,8.28,1.2,9.13,9.13,0.141,0,0,0.5,2.7
ENSMUSG00000031826,USP10,ubiquitin specific peptidase 10,nucleus|cytoplasm|endosome|early endosome|intermediate filament cytoskeleton|,"DNA repair|proteolysis|ubiquitin-dependent protein catabolic process|autophagy|cellular response to DNA damage stimulus|regulation of autophagy|protein deubiquitination|DNA damage response, signal transduction by p53 class mediator|",p53 binding|cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|ion channel binding|poly(A) RNA binding|,10,0.8,9.97,10,0.3,1.27,0.8,9.12,9.12,0.141,0,0,0.3,1.6
ENSMUSG00000015149,SIRT2,sirtuin 2,nucleus|nucleus|chromosome|nuclear heterochromatin|cytoplasm|cytoplasm|centrosome|centriole|spindle|cytosol|cytoskeleton|microtubule|plasma membrane|membrane|midbody|midbody|paranodal junction|paranodal junction|paranode region of axon|cell projection|perikaryon|perikaryon|myelin sheath|myelin sheath|lateral loop|Schmidt-Lanterman incisure|Schmidt-Lanterman incisure|juxtaparanode region of axon|perinuclear region of cytoplasm|mitotic spindle|meiotic spindle|glial cell projection|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|protein deacetylation|protein deacetylation|protein deacetylation|autophagy|cell cycle|mitotic nuclear division|meiotic nuclear division|nervous system development|negative regulation of cell proliferation|negative regulation of autophagy|negative regulation of peptidyl-threonine phosphorylation|phosphatidylinositol 3-kinase signaling|histone deacetylation|myelination in peripheral nervous system|myelination in peripheral nervous system|cell differentiation|regulation of myelination|regulation of myelination|peptidyl-lysine deacetylation|cellular response to hepatocyte growth factor stimulus|negative regulation of protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|protein kinase B signaling|cellular lipid catabolic process|regulation of fat cell differentiation|negative regulation of fat cell differentiation|positive regulation of meiosis|negative regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|hepatocyte growth factor receptor signaling pathway|cell division|regulation of cell cycle|positive regulation of cell division|positive regulation of attachment of spindle microtubules to kinetochore|negative regulation of transcription from RNA polymerase II promoter in response to hypoxia|negative regulation of oligodendrocyte progenitor proliferation|histone H3 deacetylation|histone H3 deacetylation|histone H4 deacetylation|histone H4 deacetylation|cellular response to molecule of bacterial origin|cellular response to hypoxia|cellular response to epinephrine stimulus|tubulin deacetylation|tubulin deacetylation|tubulin deacetylation|positive regulation of oocyte maturation|negative regulation of NLRP3 inflammasome complex assembly|negative regulation of defense response to bacterium|negative regulation of defense response to bacterium|ripoptosome assembly involved in necroptotic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia|","chromatin binding|histone deacetylase activity|histone deacetylase activity|protein binding|transcription factor binding|zinc ion binding|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|protein deacetylase activity|protein deacetylase activity|protein deacetylase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|NAD-dependent protein deacetylase activity|histone acetyltransferase binding|histone deacetylase binding|tubulin deacetylase activity|tubulin deacetylase activity|ubiquitin binding|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|metal ion binding|NAD-dependent histone deacetylase activity (H4-K16 specific)|N-acetylgalactosamine-6-phosphate deacetylase activity|beta-tubulin binding|NAD binding|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|NAD+ binding|",10,0.8,5.28,10,0.8,4.2,0.8,9.12,9.12,0.141,0,0,0.2,1.4
ENSMUSG00000003402,PRKCSH,protein kinase C substrate 80K-H,endoplasmic reticulum|endoplasmic reticulum|glucosidase II complex|,in utero embryonic development|liver development|N-glycan processing|nitrogen compound metabolic process|negative regulation of neuron projection development|phosphorylation|protein heterooligomerization|renal system development|,RNA binding|protein kinase C binding|calcium ion binding|protein binding|kinase activity|transferase activity|ion channel binding|metal ion binding|phosphoprotein binding|,10,0.2,0.972,10,0.9,10.7,0.9,9.05,9.05,0.142,0,0,0.2,1.6
ENSMUSG00000041859,MCM3,minichromosome maintenance deficient 3 (S. cerevisiae),nucleus|nucleus|cytoplasm|centrosome|membrane|MCM complex|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,DNA replication|DNA replication initiation|cell cycle|,nucleotide binding|DNA binding|DNA helicase activity|helicase activity|ATP binding|hydrolase activity|,7,0.9,5.36,8,0.7,4.29,0.8,9.04,9.04,0.143,0,0,0.3,1.7
ENSMUSG00000085793,LIN52,lin-52 homolog (C. elegans),cellular_component|DRM complex|,"transcription, DNA-templated|cell cycle|biological_process|",molecular_function|,8,-0.8,6.37,7,-0.9,3.03,-0.8,9.01,-9.01,0.143,0,0,-2,0.3
ENSMUSG00000026355,MCM6,"minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)",nucleus|nucleus|MCM complex|,DNA replication|DNA unwinding involved in DNA replication|DNA replication initiation|cell cycle|,nucleotide binding|DNA binding|DNA helicase activity|single-stranded DNA binding|ATP-dependent DNA helicase activity|helicase activity|protein binding|ATP binding|hydrolase activity|identical protein binding|,5,1,4.17,4,1.3,5.33,1.3,8.98,8.98,0.144,0,0,0.5,2
ENSMUSG00000027452,ACSS1,acyl-CoA synthetase short-chain family member 1,mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial matrix|,acetyl-CoA biosynthetic process|acetyl-CoA biosynthetic process|metabolic process|acetate biosynthetic process|acetyl-CoA biosynthetic process from acetate|propionate biosynthetic process|,nucleotide binding|catalytic activity|acetate-CoA ligase activity|acetate-CoA ligase activity|ATP binding|AMP binding|ligase activity|,10,1.1,7.57,10,1.4,2.1,1.2,8.97,8.97,0.144,0,0,0.5,2.7
ENSMUSG00000063550,NUP98,nucleoporin 98,kinetochore|nucleus|nuclear envelope|nuclear pore|nucleoplasm|membrane|nuclear pore outer ring|nuclear membrane|nuclear periphery|nuclear inclusion body|nuclear pore nuclear basket|,"protein import into nucleus, docking|DNA replication|transport|protein transport|mRNA transport|nuclear pore complex assembly|",structural constituent of nuclear pore|peptide binding|,10,-1.2,8.33,10,-0.4,2.44,-0.5,8.9,-8.9,0.145,0,0,-1.7,-0.3
ENSMUSG00000003308,KEAP1,kelch-like ECH-associated protein 1,nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|microtubule organizing center|cell-cell adherens junction|focal adhesion|midbody|Cul3-RING ubiquitin ligase complex|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|proteasomal ubiquitin-independent protein catabolic process|negative regulation of gene expression|protein ubiquitination|cytoplasmic sequestering of transcription factor|regulation of epidermal cell differentiation|protein oligomerization|cellular response to interleukin-4|",protein binding|,8,-0.2,0.746,8,-0.9,10.5,-0.9,8.89,-8.89,0.145,0,0,-1.9,-0.4
ENSMUSG00000026536,MNDA,myeloid cell nuclear differentiation antigen,nucleus|nucleolus|cytoplasm|membrane|nuclear speck|nuclear periphery|,biological_process|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,10,-1.5,11.6,10,-0.1,0.227,-1.5,8.87,-8.87,0.145,0,0,-3,-0.5
ENSMUSG00000033075,SENP1,SUMO1/sentrin specific peptidase 1,nucleus|cytoplasm|focal adhesion|nuclear membrane|,proteolysis|activation of cysteine-type endopeptidase activity involved in apoptotic process|multicellular organismal development|regulation of definitive erythrocyte differentiation|protein desumoylation|protein desumoylation|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of transcription from RNA polymerase II promoter|apoptotic signaling pathway|,protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|SUMO-specific protease activity|SUMO-specific protease activity|,10,0.7,7.12,10,0.5,2.14,0.6,8.86,8.86,0.146,0,0,0.2,1.4
ENSMUSG00000037259,DZANK1,double zinc ribbon and ankyrin repeat domains 1,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.8,3.57,10,-0.7,5.7,-0.7,8.85,-8.85,0.146,0,0,-1.6,-0.2
ENSMUSG00000026202,TUBA4A,"tubulin, alpha 4A",cytoplasm|cytoskeleton|microtubule|protein complex|extracellular vesicular exosome|,GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,1.4,1.44,10,1.1,8.1,1.3,8.81,8.81,0.147,0,0,0.4,2.4
ENSMUSG00000079553,KIFC1,kinesin family member C1,intracellular|cell|nucleus|kinesin complex|membrane|endocytic vesicle|spindle pole centrosome|mitotic spindle|,negative regulation of centrosome duplication|vesicle transport along microtubule|minus-end-directed vesicle transport along microtubule|,microtubule motor activity|protein binding|minus-end-directed microtubule motor activity|,10,0.2,0.263,9,1.4,11.4,1.3,8.8,8.8,0.147,0,0,0.6,2
ENSMUSG00000035177,NLRP2,"NLR family, pyrin domain containing 2",cytoplasm|,positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of interleukin-1 beta secretion|,nucleotide binding|ATP binding|Pyrin domain binding|,10,0.5,2.79,10,-0.7,11.5,-0.7,8.78,-8.78,0.147,0,0,-1.6,-0.2
ENSMUSG00000054717,HMGB2,high mobility group box 2,condensed chromosome|extracellular space|nucleus|nucleus|chromosome|cytoplasm|protein complex|perinuclear region of cytoplasm|,"positive regulation of endothelial cell proliferation|base-excision repair, DNA ligation|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|spermatogenesis|spermatid nucleus differentiation|male gonad development|positive regulation of nuclease activity|positive regulation of DNA binding|positive regulation of DNA binding|positive regulation of erythrocyte differentiation|positive regulation of megakaryocyte differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|response to steroid hormone|positive chemotaxis|cell chemotaxis|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|","DNA binding|damaged DNA binding|sequence-specific DNA binding transcription factor activity|DNA binding, bending|protein domain specific binding|chemoattractant activity|transcription regulatory region DNA binding|poly(A) RNA binding|RAGE receptor binding|",10,-0.4,4.41,10,-0.7,5.09,-0.5,8.73,-8.73,0.148,0,0,-1.5,-0.1
ENSMUSG00000041797,ABCA9,"ATP-binding cassette, sub-family A (ABC1), member 9",mitochondrion|membrane|integral component of membrane|,transport|,nucleotide binding|ATP binding|ATPase activity|,10,-1,6.8,10,-1.1,2.36,-1,8.7,-8.7,0.148,0,0,-2,-0.6
ENSMUSG00000026276,2-Sep,septin 2,"exocyst|chromosome, centromeric region|kinetochore|nucleus|chromosome|nucleolus|cytoplasm|actomyosin contractile ring|cytoskeleton|spindle microtubule|plasma membrane|cell cortex|cell surface|actin cytoskeleton|actin cytoskeleton|microtubule cytoskeleton|membrane|midbody|septin complex|ciliary transition zone|cell projection|synapse|perinuclear region of cytoplasm|ciliary membrane|extracellular vesicular exosome|",cytokinesis|regulation of L-glutamate transport|GTP catabolic process|cell cycle|mitotic nuclear division|smoothened signaling pathway|neuron projection development|regulation of protein localization|regulation of protein localization|cilium assembly|regulation of catalytic activity|protein polymerization|cell division|,nucleotide binding|GTPase activity|protein binding|GTP binding|enzyme regulator activity|protein complex scaffold|identical protein binding|,10,-1.1,2.13,10,1.6,11,0.9,8.69,8.69,0.148,0,0,0.5,2.9
ENSMUSG00000036309,SKP1A,S-phase kinase-associated protein 1A,cytosol|SCF ubiquitin ligase complex|SCF ubiquitin ligase complex|Cul7-RING ubiquitin ligase complex|Cul7-RING ubiquitin ligase complex|PcG protein complex|extracellular vesicular exosome|,ubiquitin-dependent protein catabolic process|protein ubiquitination|protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|histone H2A monoubiquitination|,ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|,10,-0.4,2.7,9,1.5,11.8,1.5,8.62,8.62,0.15,0,0,-0.3,3
ENSMUSG00000002210,SMG9,"smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)",intracellular|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|",identical protein binding|,10,0.9,1.66,10,0.6,7.61,0.7,8.54,8.54,0.151,0,0,0.3,1.7
ENSMUSG00000005968,TUFT1,tuftelin 1,extracellular region|cytoplasm|,biomineral tissue development|,protein binding|,9,-0.7,4.83,9,-0.6,4.06,-0.7,8.52,-8.52,0.151,0,0,-1.4,-0.2
ENSMUSG00000031712,IL15,interleukin 15,extracellular region|extracellular space|nucleus|cytoplasm|cytoplasm|cell surface|,natural killer cell differentiation|NK T cell proliferation|immune response|positive regulation of cell proliferation|hyaluronan metabolic process|positive regulation of interleukin-17 production|positive regulation of natural killer cell proliferation|positive regulation of natural killer cell differentiation|positive regulation of natural killer cell differentiation|positive regulation of T cell proliferation|positive regulation of tyrosine phosphorylation of Stat3 protein|extrathymic T cell selection|regulation of T cell differentiation|cell maturation|lymph node development|negative regulation of smooth muscle cell proliferation|regulation of defense response to virus by host|positive regulation of immune response|,cytokine activity|cytokine activity|cytokine receptor binding|,9,-0.5,3.74,9,0.8,7.85,0.6,8.49,8.49,0.152,0,0,-0.8,2
ENSMUSG00000037262,KIN,antigenic determinant of rec-A protein,nucleus|cytoplasm|nuclear matrix|,DNA replication|DNA replication|DNA repair|DNA recombination|mRNA processing|response to stress|cellular response to DNA damage stimulus|,DNA binding|double-stranded DNA binding|RNA binding|metal ion binding|,7,0.7,5.61,6,0.9,3.26,0.7,8.43,8.43,0.153,0,0,0.2,1.7
ENSMUSG00000030610,DET1,de-etiolated homolog 1 (Arabidopsis),cellular_component|nucleus|,biological_process|,molecular_function|,10,0.5,4.14,10,0.7,5.04,0.6,8.39,8.39,0.154,0,0,0.2,1.2
ENSMUSG00000060098,PRMT7,protein arginine N-methyltransferase 7,nucleus|nucleolus|cytoplasm|cytosol|cytosol|plasma membrane|,"spliceosomal snRNP assembly|regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|protein methylation|chromatin modification|histone methylation|peptidyl-arginine methylation|peptidyl-arginine methylation, to symmetrical-dimethyl arginine|peptidyl-arginine methylation, to symmetrical-dimethyl arginine|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|cell differentiation|methylation|histone arginine methylation|histone arginine methylation|DNA methylation involved in gamete generation|histone H4-R3 methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|[myelin basic protein]-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N monomethyltransferase activity|protein-arginine omega-N monomethyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|protein-arginine omega-N symmetric methyltransferase activity|protein-arginine omega-N symmetric methyltransferase activity|ribonucleoprotein complex binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|histone methyltransferase activity (H4-R3 specific)|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,0.0712,10,-0.7,8.99,-0.6,8.39,-8.39,0.154,0,0,-1.5,-0.2
ENSMUSG00000053477,TCF4,transcription factor 4,nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|multicellular organismal development|nervous system development|cell differentiation|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein-DNA complex assembly|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase recruiting transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|TFIIB-class binding transcription factor activity|TFIIB-class transcription factor binding|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|protein C-terminus binding|bHLH transcription factor binding|protein heterodimerization activity|protein dimerization activity|E-box binding|,10,-0.5,4.83,10,-0.4,3.96,-0.4,8.37,-8.37,0.154,0,0,-0.9,-0.1
ENSMUSG00000030042,POLE4,"polymerase (DNA-directed), epsilon 4 (p12 subunit)",intracellular|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|epsilon DNA polymerase complex|,histone H3 acetylation|,molecular_function|DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|sequence-specific DNA binding|protein heterodimerization activity|,9,0.8,7.5,9,1,1.46,0.8,8.35,8.35,0.155,0,0,0.3,1.7
ENSMUSG00000037474,DTL,denticleless homolog (Drosophila),nucleus|chromosome|cytoplasm|centrosome|cytoskeleton|membrane|Cul4A-RING E3 ubiquitin ligase complex|Cul4B-RING E3 ubiquitin ligase complex|intracellular membrane-bounded organelle|,protein polyubiquitination|DNA replication|ubiquitin-dependent protein catabolic process|protein monoubiquitination|cellular response to DNA damage stimulus|response to UV|translesion synthesis|G2 DNA damage checkpoint|regulation of cell cycle|,ubiquitin-protein transferase activity|,6,1.6,3.67,6,1.1,5.26,1.3,8.32,8.32,0.155,0,0,0.4,3
ENSMUSG00000030528,BLM,"Bloom syndrome, RecQ helicase-like","nuclear chromosome|chromosome, telomeric region|lateral element|male germ cell nucleus|intracellular|nucleus|replication fork|nucleolus|cytoplasm|nuclear matrix|PML body|PML body|pronucleus|","regulation of cyclin-dependent protein serine/threonine kinase activity|telomere maintenance|DNA double-strand break processing|DNA strand renaturation|ATP catabolic process|ATP catabolic process|DNA replication|DNA repair|DNA recombination|cellular response to DNA damage stimulus|response to X-ray|replication fork processing|DNA duplex unwinding|DNA duplex unwinding|cellular metabolic process|positive regulation of transcription, DNA-templated|negative regulation of DNA recombination|negative regulation of mitotic recombination|alpha-beta T cell differentiation|positive regulation of alpha-beta T cell proliferation|regulation of binding|protein oligomerization|chromosome organization|negative regulation of cell division|negative regulation of thymocyte apoptotic process|negative regulation of thymocyte apoptotic process|cellular response to ionizing radiation|cellular response to hydroxyurea|cellular response to camptothecin|","nucleotide binding|bubble DNA binding|p53 binding|nucleic acid binding|DNA binding|single-stranded DNA binding|catalytic activity|ATP-dependent DNA helicase activity|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|four-way junction helicase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|ATPase activity|annealing helicase activity|ATP-dependent 3'-5' DNA helicase activity|G-quadruplex DNA binding|",10,0.8,1.44,10,1.5,8.23,0.8,8.31,8.31,0.155,0,0,0.2,2.5
ENSMUSG00000031583,WRN,Werner syndrome homolog (human),intracellular|nucleus|nucleoplasm|nucleoplasm|nucleolus|centrosome|MutLalpha complex|,telomere maintenance|telomere maintenance|telomere maintenance|DNA synthesis involved in DNA repair|replicative cell aging|nucleobase-containing compound metabolic process|ATP catabolic process|DNA metabolic process|DNA metabolic process|DNA replication|DNA replication|DNA repair|base-excision repair|double-strand break repair|DNA recombination|cellular response to DNA damage stimulus|response to oxidative stress|cell aging|metabolic process|cellular response to starvation|response to UV-C|multicellular organismal aging|multicellular organismal aging|replication fork processing|nucleolus to nucleoplasm transport|DNA duplex unwinding|regulation of growth rate|regulation of apoptotic process|cellular metabolic process|positive regulation of hydrolase activity|cellular response to gamma radiation|nucleic acid phosphodiester bond hydrolysis|nucleic acid phosphodiester bond hydrolysis|,nucleotide binding|magnesium ion binding|Y-form DNA binding|bubble DNA binding|nucleic acid binding|DNA binding|DNA helicase activity|catalytic activity|ATP-dependent DNA helicase activity|helicase activity|nuclease activity|exonuclease activity|protein binding|ATP binding|ATP-dependent helicase activity|3'-5' exonuclease activity|3'-5' exonuclease activity|four-way junction helicase activity|hydrolase activity|ATPase activity|manganese ion binding|protein complex binding|phosphoric ester hydrolase activity|protein homodimerization activity|3'-5' DNA helicase activity|ATP-dependent 3'-5' DNA helicase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|G-quadruplex DNA binding|,10,-1.1,4.11,10,-0.6,5.74,-0.7,8.3,-8.3,0.156,0,0,-1.7,-0.3
ENSMUSG00000047407,TGIF1,TGFB-induced factor homeobox 1,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|determination of left/right symmetry|negative regulation of cell proliferation|dorsal/ventral pattern formation|regulation of gastrulation|negative regulation of gene expression|nodal signaling pathway|positive regulation of neuron differentiation|positive regulation of fibroblast proliferation|negative regulation of retinoic acid receptor signaling pathway|retina development in camera-type eye|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|protein binding|JUN kinase binding|co-SMAD binding|,5,0.8,5.49,5,0.6,3.26,0.7,8.29,8.29,0.156,0,0,0.3,1.8
ENSMUSG00000039105,ATP6V1G1,"ATPase, H+ transporting, lysosomal V1 subunit G1",intracellular|lysosomal membrane|lysosomal membrane|cytosol|plasma membrane|plasma membrane|vacuolar proton-transporting V-type ATPase complex|extracellular vesicular exosome|,ATP catabolic process|transport|ion transport|proton transport|hydrogen ion transmembrane transport|,"protein binding|hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|ATPase activity|ATPase binding|",7,-0.9,6.87,8,1.2,3.42,-0.9,8.21,-8.21,0.158,0,0,-2,1.2
ENSMUSG00000020430,PES1,"pescadillo homolog 1, containing BRCT domain (zebrafish)","condensed chromosome|nucleus|nucleoplasm|chromosome|nucleolus|nucleolus|cytoplasm|membrane|preribosome, large subunit precursor|PeBoW complex|PeBoW complex|","maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|rRNA processing|rRNA processing|rRNA processing|nucleolus organization|cell proliferation|protein localization to organelle|ribosome biogenesis|regulation of cell cycle|",protein binding|poly(A) RNA binding|,6,-0.7,6.74,6,1.7,10.9,1.7,8.18,8.18,0.158,0,0,-1,3
ENSMUSG00000020402,VDAC1,voltage-dependent anion channel 1,nucleus|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial inner membrane|plasma membrane|membrane|integral component of membrane|mitochondrial nucleoid|protein complex|pore complex|extracellular vesicular exosome|,behavioral fear response|transport|ion transport|anion transport|mitochondrial calcium ion transport|apoptotic process|synaptic transmission|neuron-neuron synaptic transmission|learning|ion transmembrane transport|regulation of ion transmembrane transport|regulation of anion transport|transmembrane transport|,nucleotide binding|anion channel activity|voltage-gated anion channel activity|voltage-gated anion channel activity|porin activity|protein complex binding|,10,0.5,3.09,10,1.2,7.21,0.9,8.16,8.16,0.159,0,0,0.3,1.8
ENSMUSG00000021147,WDR37,WD repeat domain 37,cellular_component|,biological_process|,molecular_function|,10,-0.7,7.16,10,-0.5,1.34,-0.6,8.16,-8.16,0.159,0,0,-1.4,-0.2
ENSMUSG00000028933,XRCC2,X-ray repair complementing defective repair in Chinese hamster cells 2,nucleus|replication fork|centrosome|Rad51B-Rad51C-Rad51D-XRCC2 complex|,mitotic cell cycle|double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|in utero embryonic development|DNA metabolic process|DNA repair|DNA recombination|cellular response to DNA damage stimulus|response to X-ray|response to gamma radiation|strand invasion|negative regulation of neuron apoptotic process|positive regulation of neurogenesis|centrosome organization|,four-way junction DNA binding|DNA binding|ATP binding|DNA-dependent ATPase activity|,10,0.5,3.17,10,0.7,5.84,0.7,8.11,8.11,0.16,0,0,0.2,1.4
ENSMUSG00000068037,MAS1,MAS1 oncogene,intracellular|plasma membrane|cell surface|membrane|integral component of membrane|,negative regulation of protein phosphorylation|signal transduction|G-protein coupled receptor signaling pathway|activation of NF-kappaB-inducing kinase activity|spermatogenesis|positive regulation of cell proliferation|angiotensin-activated signaling pathway|angiotensin-activated signaling pathway|positive regulation of DNA replication|regulation of inflammatory response|regulation of inflammatory response|positive regulation of inositol phosphate biosynthetic process|protein kinase C signaling|,angiotensin receptor activity|angiotensin receptor activity|signal transducer activity|G-protein coupled receptor activity|peptide hormone binding|peptide binding|,10,0.6,2.32,10,1.7,9.2,1.6,8.07,8.07,0.161,0,0,0.3,2.8
ENSMUSG00000025857,HEATR2,HEAT repeat containing 2,cellular_component|,biological_process|,molecular_function|,10,1.3,3.65,9,0.5,5.05,1.2,8.01,8.01,0.162,0,0,0.2,2.6
ENSMUSG00000033871,PPARGC1B,"peroxisome proliferative activated receptor, gamma, coactivator 1 beta",nucleus|mitochondrion|mediator complex|,"ossification|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from mitochondrial promoter|actin filament organization|positive regulation of alkaline phosphatase activity|intracellular estrogen receptor signaling pathway|cellular response to reactive oxygen species|positive regulation of phosphorylation|positive regulation of osteoclast differentiation|positive regulation of bone resorption|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|bone trabecula formation|positive regulation of receptor activity|",nucleotide binding|RNA polymerase II transcription cofactor activity|nucleic acid binding|RNA binding|protein binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|receptor activator activity|AF-2 domain binding|,9,-0.7,0.648,9,-0.5,7.82,-0.5,7.99,-7.99,0.163,0,0,-1.3,-0.1
ENSMUSG00000031561,TENM3,teneurin transmembrane protein 3,integral component of plasma membrane|membrane|integral component of membrane|cell projection|,cell adhesion|homophilic cell adhesion|signal transduction|positive regulation of neuron projection development|positive regulation of neuron projection development|cell differentiation|camera-type eye morphogenesis|self proteolysis|,protein homodimerization activity|protein heterodimerization activity|,10,2.1,11.2,10,-0.7,0.0881,1.8,7.98,7.98,0.163,0,0,0.3,4
ENSMUSG00000020471,POLD2,"polymerase (DNA directed), delta 2, regulatory subunit",nucleus|delta DNA polymerase complex|,DNA replication|DNA-dependent DNA replication|DNA biosynthetic process|,DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|,7,-0.8,7.66,7,-0.4,1.19,-0.7,7.97,-7.97,0.163,0,0,-2,1.7
ENSMUSG00000029030,TPRGL,transformation related protein 63 regulated like,synaptic vesicle|synaptic vesicle|cell junction|cytoplasmic vesicle|synapse|extracellular vesicular exosome|,biological_process|,protein binding|identical protein binding|,10,-0.6,4.15,10,-0.6,4.17,-0.6,7.97,-7.97,0.163,0,0,-1.3,-0.1
ENSMUSG00000090083,RNF8,ring finger protein 8,"ubiquitin ligase complex|chromosome, telomeric region|nucleus|chromosome|nucleolus|site of double-strand break|",DNA repair|double-strand break repair|double-strand break repair via nonhomologous end joining|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|spermatid development|response to ionizing radiation|protein ubiquitination|chromatin modification|histone H2A ubiquitination|histone H2A ubiquitination|histone H2B ubiquitination|histone exchange|isotype switching|positive regulation of DNA repair|negative regulation of translational elongation|cell division|protein autoubiquitination|protein K63-linked ubiquitination|histone H2A K63-linked ubiquitination|protein K48-linked ubiquitination|,"chromatin binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|histone binding|histone binding|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",1,1.4,7.78,1,0.5,1.05,1.4,7.96,7.96,0.164,0,0,0.5,2
ENSMUSG00000021374,NUP153,nucleoporin 153,nuclear pore|nuclear lamina|nucleolus|cytoplasm|nuclear membrane|nuclear periphery|nuclear inclusion body|protein complex|nuclear pore nuclear basket|,nucleocytoplasmic transport|negative regulation of RNA export from nucleus|nuclear pore complex assembly|,nucleocytoplasmic transporter activity|protein binding|zinc ion binding|Ran GTPase binding|structural constituent of nuclear pore|identical protein binding|protein anchor|,10,-0.7,10.3,10,1.2,3.39,-0.7,7.95,-7.95,0.164,0,0,-2,0.7
ENSMUSG00000079109,PMS2,postmeiotic segregation increased 2 (S. cerevisiae),nucleus|cytoplasm|microtubule cytoskeleton|mismatch repair complex|MutLalpha complex|,ATP catabolic process|DNA repair|mismatch repair|mismatch repair|mismatch repair|mismatch repair|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|meiotic nuclear division|somatic hypermutation of immunoglobulin genes|somatic recombination of immunoglobulin gene segments|,DNA binding|single-stranded DNA binding|single-stranded DNA binding|nuclease activity|endonuclease activity|ATP binding|hydrolase activity|ATPase activity|mismatched DNA binding|single base insertion or deletion binding|MutSalpha complex binding|,10,0.7,6.7,10,0.4,2.14,0.6,7.92,7.92,0.164,0,0,0.2,1.4
ENSMUSG00000028367,TXN1,thioredoxin 1,extracellular region|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|cytosol|cytosol|axon|dendrite|neuronal cell body|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|glycerol ether metabolic process|transport|response to radiation|regulation of protein import into nucleus, translocation|positive regulation of DNA binding|cell redox homeostasis|negative regulation of protein export from nucleus|oxidation-reduction process|oxidation-reduction process|",protein binding|protein disulfide oxidoreductase activity|peptide disulfide oxidoreductase activity|enzyme binding|poly(A) RNA binding|,6,-1.2,5.57,6,-1,2.9,-1.2,7.92,-7.92,0.164,0,0,-2,-0.5
ENSMUSG00000006678,POLA1,"polymerase (DNA directed), alpha 1",chromatin|nucleus|nucleus|nuclear envelope|nucleoplasm|alpha DNA polymerase:primase complex|alpha DNA polymerase:primase complex|cytoplasm|nuclear matrix|,"mitotic S phase|nucleobase-containing compound metabolic process|DNA replication|DNA replication|DNA replication|DNA-dependent DNA replication|DNA replication, synthesis of RNA primer|DNA replication initiation|DNA strand elongation involved in DNA replication|leading strand elongation|lagging strand elongation|double-strand break repair via nonhomologous end joining|double-strand break repair via nonhomologous end joining|cell proliferation|translesion synthesis|DNA biosynthetic process|nucleic acid phosphodiester bond hydrolysis|","nucleotide binding|nucleoside binding|nucleic acid binding|DNA binding|chromatin binding|double-stranded DNA binding|DNA-directed DNA polymerase activity|DNA-directed DNA polymerase activity|DNA primase activity|protein binding|3'-5' exonuclease activity|transferase activity|nucleotidyltransferase activity|purine nucleotide binding|pyrimidine nucleotide binding|metal ion binding|protein heterodimerization activity|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",9,-1.1,3.85,9,-0.8,4.75,-1,7.89,-7.89,0.165,0,0,-2,-0.4
ENSMUSG00000004789,DLST,dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex),nucleus|mitochondrion|mitochondrion|plasma membrane|membrane|intracellular membrane-bounded organelle|oxoglutarate dehydrogenase complex|extracellular vesicular exosome|,tricarboxylic acid cycle|2-oxoglutarate metabolic process|NADH metabolic process|metabolic process|,"dihydrolipoyllysine-residue succinyltransferase activity|transferase activity|transferase activity, transferring acyl groups|heat shock protein binding|chaperone binding|",7,-1,5.53,8,-1.2,2.97,-1.1,7.87,-7.87,0.166,0,0,-2,0.3
ENSMUSG00000028948,NOL9,nucleolar protein 9,nucleus|membrane|,maturation of 5.8S rRNA|rRNA processing|phosphorylation|,"nucleotide binding|RNA binding|ATP binding|phosphofructokinase activity|phosphorylase kinase regulator activity|cobinamide kinase activity|phytol kinase activity|kinase activity|phosphatidylinositol phosphate kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|phenol kinase activity|cyclin-dependent protein kinase activating kinase regulator activity|inositol tetrakisphosphate 2-kinase activity|heptose 7-phosphate kinase activity|aminoglycoside phosphotransferase activity|phosphatidylinositol 3-kinase activity|eukaryotic elongation factor-2 kinase regulator activity|eukaryotic elongation factor-2 kinase activator activity|LPPG:FO 2-phospho-L-lactate transferase activity|cytidine kinase activity|glycerate 2-kinase activity|(S)-lactate 2-kinase activity|phosphoserine:homoserine phosphotransferase activity|L-seryl-tRNA(Sec) kinase activity|phosphocholine transferase activity|polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide kinase activity|GTP-dependent polynucleotide kinase activity|farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|geraniol kinase activity|geranylgeraniol kinase activity|CTP:geranylgeraniol kinase activity|prenol kinase activity|1-phosphatidylinositol-5-kinase activity|1-phosphatidylinositol-3-phosphate 4-kinase activity|phosphatidylinositol-3,4-bisphosphate 5-kinase activity|phosphatidylinositol bisphosphate kinase activity|inositol-3,4,6-trisphosphate 1-kinase activity|inositol 5-diphosphate pentakisphosphate 5-kinase activity|inositol diphosphate tetrakisphosphate kinase activity|",7,0.7,6.95,7,-0.3,1.48,0.7,7.86,7.86,0.166,0,0,-1.7,2
ENSMUSG00000002055,SPAG5,sperm associated antigen 5,"chromosome, centromeric region|kinetochore|kinetochore|chromosome|cytoplasm|spindle|cytoskeleton|microtubule|spindle microtubule|microtubule plus-end|mitotic spindle|",mitotic sister chromatid segregation|cell cycle|spindle organization|chromosome segregation|mitotic nuclear division|cell division|regulation of attachment of spindle microtubules to kinetochore|,microtubule binding|,10,1.5,1.47,10,0.8,7.84,1.3,7.83,7.83,0.166,0,0,0.3,2.5
ENSMUSG00000024073,BIRC6,baculoviral IAP repeat-containing 6,spindle pole|cytoplasm|endosome|Golgi apparatus|trans-Golgi network|microtubule organizing center|cytoskeleton|membrane|membrane|midbody|,placenta development|apoptotic process|cell cycle|mitotic nuclear division|positive regulation of cell proliferation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|protein ubiquitination|protein ubiquitination|regulation of cytokinesis|regulation of cell proliferation|negative regulation of apoptotic process|negative regulation of apoptotic process|cell division|labyrinthine layer development|spongiotrophoblast layer development|negative regulation of extrinsic apoptotic signaling pathway|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|cysteine-type endopeptidase inhibitor activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|peptidase inhibitor activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,1.6,10.7,1.6,7.83,7.83,0.166,0,0,0.3,3
ENSMUSG00000056216,CEBPG,"CCAAT/enhancer binding protein (C/EBP), gamma",nucleus|nucleus|,"nucleosome disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|immune response|mRNA metabolic process|natural killer cell mediated cytotoxicity|enucleate erythrocyte differentiation|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of interferon-gamma biosynthetic process|positive regulation of DNA repair|",DNA binding|DNA binding|double-stranded DNA binding|protein binding|transcription factor binding|transcription factor binding|protein homodimerization activity|sequence-specific DNA binding|protein heterodimerization activity|,10,0,0,10,1.7,10.9,1.6,7.82,7.82,0.167,0,0,-0.3,3
ENSMUSG00000023905,TNFRSF12A,"tumor necrosis factor receptor superfamily, member 12a",ruffle|plasma membrane|cell surface|membrane|integral component of membrane|,"angiogenesis|apoptotic process|substrate-dependent cell migration, cell attachment to substrate|cell adhesion|multicellular organismal development|cell differentiation|positive regulation of apoptotic process|positive regulation of axon extension|regulation of wound healing|extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|",protein binding|,10,0,0,10,1.6,10.7,1.6,7.79,7.79,0.167,0,0,0.2,2.8
ENSMUSG00000015747,VPS45,vacuolar protein sorting 45 (yeast),Golgi membrane|endosome|Golgi apparatus|endosome membrane|membrane|integral component of membrane|,transport|vesicle docking involved in exocytosis|biological_process|protein transport|vesicle-mediated transport|,protein binding|,9,-0.2,0.186,9,1,10.1,0.9,7.79,7.79,0.167,0,0,0.2,1.8
ENSMUSG00000028312,SMC2,structural maintenance of chromosomes 2,nuclear chromosome|condensed chromosome|condensed chromosome|condensin complex|nucleus|chromosome|cytoplasm|extracellular vesicular exosome|,cell cycle|mitotic nuclear division|mitotic chromosome condensation|meiotic chromosome condensation|chromosome condensation|meiotic chromosome segregation|chromosome organization|cell division|kinetochore organization|,nucleotide binding|protein binding|ATP binding|protein heterodimerization activity|,8,0.4,1.65,7,1.1,7.24,0.6,7.72,7.72,0.169,0,0,0.2,1.9
ENSMUSG00000052837,JUNB,jun B proto-oncogene,nucleus|,"vasculogenesis|osteoblast differentiation|in utero embryonic development|trophectodermal cell differentiation|trophectodermal cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular process|osteoclast differentiation|osteoblast proliferation|positive regulation of cell differentiation|decidualization|regulation of cell cycle|embryonic process involved in female pregnancy|labyrinthine layer blood vessel development|cellular response to calcium ion|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0.4,1.48,10,1.7,8.69,1.6,7.68,7.68,0.17,0,0,0.4,3
ENSMUSG00000023919,CENPQ,centromere protein Q,"chromosome, centromeric region|nucleus|chromosome|cytoplasm|intermediate filament cytoskeleton|",None,None,9,1.5,6.12,10,0.7,4.11,0.8,7.67,7.67,0.17,0,0,0.4,2.6
ENSMUSG00000025049,TAF5,"TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|actin cytoskeleton|transcription factor TFTC complex|intracellular membrane-bounded organelle|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|histone acetylation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|histone acetyltransferase activity|transcription regulatory region DNA binding|protein dimerization activity|,7,1,8.78,8,0.4,0.799,0.9,7.65,7.65,0.171,0,0,0.4,2
ENSMUSG00000005893,NR2C2,"nuclear receptor subfamily 2, group C, member 2",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|spermatogenesis|cerebellum development|cell differentiation|positive regulation of embryonic development|steroid hormone mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of behavior|meiotic cell cycle|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,0.9,2.73,10,0.4,5.51,0.5,7.63,7.63,0.171,0,0,0.1,1.5
ENSMUSG00000095770,GM21637,"predicted gene, 21637",None,None,None,6,0.8,4.57,4,0.7,3.43,0.8,7.6,7.6,0.172,0,0,0.2,2
ENSMUSG00000018362,KPNA2,karyopherin (importin) alpha 2,intracellular|cell|nucleus|cytoplasm|membrane|,protein import into nucleus|NLS-bearing protein import into nucleus|,protein binding|nuclear localization sequence binding|protein transporter activity|histone deacetylase binding|poly(A) RNA binding|,8,0.8,4.32,8,1.8,5.92,1.7,7.58,7.58,0.172,0,0,0.7,3
ENSMUSG00000031540,KAT6A,K(lysine) acetyltransferase 6A,nucleosome|nucleus|nucleus|Golgi apparatus|PML body|MOZ/MORF histone acetyltransferase complex|,"heart morphogenesis|heart morphogenesis|nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|protein acetylation|chromatin modification|histone acetylation|myeloid cell differentiation|somatic stem cell maintenance|embryonic hemopoiesis|aorta morphogenesis|aorta morphogenesis|negative regulation of sequence-specific DNA binding transcription factor activity|histone H3 acetylation|histone H3 acetylation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|face morphogenesis|face morphogenesis|cellular senescence|","DNA binding|chromatin binding|histone acetyltransferase activity|protein binding|transcription factor binding|zinc ion binding|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|metal ion binding|",10,-0.7,4.9,10,-0.5,3.2,-0.6,7.57,-7.57,0.173,0,0,-1.4,-0.1
ENSMUSG00000000384,TBRG4,transforming growth factor beta regulated gene 4,mitochondrion|mitochondrion|,cellular respiration|,protein kinase activity|poly(A) RNA binding|,10,-0.7,8.63,10,-0.2,1.26,-0.7,7.56,-7.56,0.173,0,0,-1.5,-0.1
ENSMUSG00000024454,HDAC3,histone deacetylase 3,histone deacetylase complex|chromatin|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|spindle microtubule|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|protein deacetylation|regulation of mitotic cell cycle|chromatin modification|histone deacetylation|histone deacetylation|histone deacetylation|circadian regulation of gene expression|regulation of multicellular organism growth|negative regulation of transcription, DNA-templated|negative regulation of JNK cascade|spindle assembly|",DNA binding|chromatin binding|chromatin binding|transcription corepressor activity|histone deacetylase activity|histone deacetylase activity|histone deacetylase activity|protein binding|transcription factor binding|transcription factor binding|hydrolase activity|enzyme binding|cyclin binding|histone deacetylase activity (H3-K14 specific)|chromatin DNA binding|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|protein deacetylase activity|histone deacetylase activity (H4-K16 specific)|histone deacetylase binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|NAD-dependent histone deacetylase activity (H3-K18 specific)|,7,1.4,9.31,7,-1.2,3.89,1.3,7.55,7.55,0.173,0,0,-0.3,3
ENSMUSG00000004698,HDAC9,histone deacetylase 9,histone deacetylase complex|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|histone methyltransferase complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|inflammatory response|nervous system development|heart development|chromatin modification|histone deacetylation|histone deacetylation|B cell differentiation|cellular response to insulin stimulus|peptidyl-lysine deacetylation|B cell activation|negative regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|regulation of skeletal muscle fiber development|regulation of striated muscle cell differentiation|histone H3 deacetylation|histone H4 deacetylation|positive regulation of cell migration involved in sprouting angiogenesis|",transcription corepressor activity|histone deacetylase activity|protein kinase C binding|protein binding|transcription factor binding|transcription factor binding|hydrolase activity|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|protein deacetylase activity|histone deacetylase activity (H4-K16 specific)|histone deacetylase binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|repressing transcription factor binding|repressing transcription factor binding|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,-0.6,5.85,10,-0.5,2.07,-0.6,7.55,-7.55,0.173,0,0,-1.4,-0.1
ENSMUSG00000022476,POLR3H,polymerase (RNA) III (DNA directed) polypeptide H,nucleus|nucleoplasm|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|centrosome|intracellular membrane-bounded organelle|,"immune system process|nucleobase-containing compound metabolic process|transcription, DNA-templated|transcription from RNA polymerase III promoter|transcription initiation from RNA polymerase III promoter|innate immune response|defense response to virus|",RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|,8,0.3,0.652,7,-1.1,8.67,-1,7.53,-7.53,0.174,0,0,-2,-0.4
ENSMUSG00000055733,NAP1L3,nucleosome assembly protein 1-like 3,cellular_component|nucleus|cytoplasm|,nucleosome assembly|biological_process|,molecular_function|,10,1.4,1.42,10,1,7.45,1,7.45,7.45,0.176,0,0,0.3,2.4
ENSMUSG00000021245,MLH3,mutL homolog 3 (E coli),condensed chromosome|synaptonemal complex|male germ cell nucleus|chiasma|mismatch repair complex|,ATP catabolic process|mismatch repair|mismatch repair|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|synaptonemal complex assembly|male meiosis|female meiosis I|protein localization|,chromatin binding|single-stranded DNA binding|ATPase activity|centromeric DNA binding|,10,0.4,1.72,10,-1.5,8.71,-1.5,7.39,-7.39,0.177,0,0,-3,-0.4
ENSMUSG00000010054,TUSC2,tumor suppressor candidate 2,mitochondrion|,natural killer cell differentiation|natural killer cell differentiation|phagocytosis|inflammatory response|interleukin-15 production|negative regulation of interleukin-17 production|positive regulation of interleukin-10 production|cell maturation|cell maturation|defense response to Gram-negative bacterium|regulation of mitochondrial membrane potential|response to defense-related host reactive oxygen species production|neutrophil mediated killing of gram-negative bacterium|chemokine (C-C motif) ligand 5 production|regulation of reactive oxygen species metabolic process|,molecular_function|,9,-0.4,2.06,10,-0.4,5.6,-0.4,7.35,-7.35,0.178,0,0,-1.1,-0.1
ENSMUSG00000058486,WDR91,WD repeat domain 91,cellular_component|,biological_process|,molecular_function|,10,0.9,5.81,10,2,4.5,1.3,7.33,7.33,0.179,0,0,0.3,3
ENSMUSG00000029866,KEL,Kell blood group,cellular_component|plasma membrane|membrane|integral component of membrane|,proteolysis|,endopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,-0.9,10.3,10,0.2,0.168,-0.8,7.32,-7.32,0.179,0,0,-1.8,-0.3
ENSMUSG00000062997,RPL35,ribosomal protein L35,cytoplasm|membrane|cytosolic large ribosomal subunit|,biological_process|,poly(A) RNA binding|,2,1.4,8.69,2,-1.3,5.98,1.4,7.3,7.3,0.18,0,0,-1.7,2
ENSMUSG00000045690,WDR89,WD repeat domain 89,cellular_component|,biological_process|,molecular_function|,10,0.8,6.15,10,1.9,4.4,1.1,7.29,7.29,0.18,0,0,0.3,2.9
ENSMUSG00000032397,TIPIN,timeless interacting protein,nuclear chromatin|nucleus|nucleus|cytoplasm|cytoplasm|Golgi apparatus|intracellular membrane-bounded organelle|,DNA replication checkpoint|DNA damage checkpoint|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|positive regulation of cell proliferation|response to UV|intra-S DNA damage checkpoint|cell cycle phase transition|replication fork protection|cell division|,protein binding|,8,-0.9,2.72,8,-0.6,5.42,-0.7,7.28,-7.28,0.18,0,0,-1.7,-0.2
ENSMUSG00000034023,FANCD2,"Fanconi anemia, complementation group D2",condensed chromosome|nucleus|nucleus|Golgi apparatus|intracellular membrane-bounded organelle|,DNA repair|cellular response to DNA damage stimulus|cell cycle|synapsis|multicellular organismal development|gamete generation|response to gamma radiation|,protein binding|DNA polymerase binding|,10,1.5,2.99,10,0.9,6.08,1.1,7.25,7.25,0.181,0,0,0.3,2.5
ENSMUSG00000096645,SPIN2E,"spindlin family, member 2E",None,None,None,6,-1.5,8.37,6,-0.4,1.51,-1.4,7.25,-7.25,0.181,0,0,-2.7,-0.2
ENSMUSG00000030796,TEAD2,TEA domain family member 2,intracellular|nucleus|transcription factor complex|,"vasculogenesis|neural tube closure|embryonic heart tube morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|notochord development|hippo signaling|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|paraxial mesoderm development|lateral mesoderm development|negative regulation of cell death|",DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|,10,-1,9.21,10,-0.2,0.689,-1,7.22,-7.22,0.182,0,0,-1.9,-0.3
ENSMUSG00000031262,CENPI,centromere protein I,"chromosome, centromeric region|kinetochore|nucleus|chromosome|",biological_process|centromere complex assembly|,molecular_function|,7,0.8,8.73,8,0.2,0.383,0.8,7.13,7.13,0.184,0,0,0.2,1.8
ENSMUSG00000020739,NUP85,nucleoporin 85,"chromosome, centromeric region|kinetochore|nucleus|nuclear pore|chromosome|cytoplasm|cytoskeleton|plasma membrane|membrane|membrane|nuclear pore outer ring|",transport|chemotaxis|protein transport|cytokine-mediated signaling pathway|lamellipodium assembly|macrophage chemotaxis|mRNA transport|,CCR2 chemokine receptor binding|,7,0.9,6.37,8,-1.3,2.45,0.6,7.12,7.12,0.185,0,0,-0.3,2
ENSMUSG00000022895,ETS2,"E26 avian leukemia oncogene 2, 3' domain",nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|glucocorticoid receptor binding|sequence-specific DNA binding|,10,0.6,7.75,10,0.2,1.34,0.5,7.1,7.1,0.185,0,0,0.1,1.2
ENSMUSG00000031095,CUL4B,cullin 4B,nucleus|cytoplasm|plasma membrane|cullin-RING ubiquitin ligase complex|Cul4B-RING E3 ubiquitin ligase complex|extracellular vesicular exosome|,DNA repair|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|cell cycle|histone H2A monoubiquitination|positive regulation of protein catabolic process|UV-damage excision repair|positive regulation of G1/S transition of mitotic cell cycle|,damaged DNA binding|ubiquitin protein ligase binding|,9,0.8,7.25,9,0.4,0.76,0.7,7.05,7.05,0.187,0,0,0.2,1.6
ENSMUSG00000001855,NUP214,nucleoporin 214,intracellular|cell|nucleus|nuclear pore|focal adhesion|intracellular membrane-bounded organelle|,mRNA export from nucleus|protein import into nucleus|protein export from nucleus|transport|protein transport|mRNA transport|regulation of cell cycle|,nucleocytoplasmic transporter activity|,10,0.7,5.04,9,0.7,2.32,0.7,7.04,7.04,0.187,0,0,-0.1,2
ENSMUSG00000020572,NAMPT,nicotinamide phosphoribosyltransferase,extracellular region|extracellular space|nucleus|cytoplasm|cytoplasm|extracellular vesicular exosome|,NAD biosynthetic process|pyridine nucleotide biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle cell proliferation|positive regulation of nitric-oxide synthase biosynthetic process|,"nicotinate-nucleotide diphosphorylase (carboxylating) activity|cytokine activity|drug binding|transferase activity|transferase activity, transferring glycosyl groups|protein homodimerization activity|nicotinamide phosphoribosyltransferase activity|nicotinamide phosphoribosyltransferase activity|",5,-0.4,2.27,4,1.2,9.31,1.2,7.02,7.02,0.188,0,0,-0.2,2
ENSMUSG00000054728,PHACTR1,phosphatase and actin regulator 1,nucleus|cytoplasm|cytosol|cell junction|synapse|,actomyosin structure organization|actomyosin structure organization|actin cytoskeleton reorganization|regulation of phosphorylation|stress fiber assembly|stress fiber assembly|cell motility|,actin binding|protein phosphatase inhibitor activity|protein phosphatase 1 binding|,10,-0.5,2.26,10,-0.6,5.18,-0.6,7.02,-7.02,0.188,0,0,-1.7,0.2
ENSMUSG00000034274,THOC5,THO complex 5,transcription export complex|THO complex|THO complex part of transcription export complex|nucleus|nucleus|cytoplasm|,"cell morphogenesis|blastocyst development|mRNA processing|mRNA export from nucleus|transport|RNA splicing|regulation of gene expression|regulation of mRNA export from nucleus|stem cell division|cell differentiation|monocyte differentiation|positive regulation of DNA-templated transcription, elongation|negative regulation of macrophage differentiation|viral mRNA export from host cell nucleus|mRNA transport|primitive hemopoiesis|negative regulation of DNA damage checkpoint|regulation of stem cell division|",RNA binding|mRNA binding|protein binding|,10,0.4,0.837,10,1.3,8.57,1.1,6.98,6.98,0.189,0,0,0.3,2.8
ENSMUSG00000041438,CIRH1A,"cirrhosis, autosomal recessive 1A (human)",nucleus|nucleolus|t-UTP complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|maturation of SSU-rRNA|",poly(A) RNA binding|,5,0.3,0.148,5,1.5,8.49,1.5,6.94,6.94,0.19,0,0,0.5,3
ENSMUSG00000007891,CTSD,cathepsin D,extracellular region|extracellular space|mitochondrion|lysosome|lysosome|extracellular matrix|extracellular vesicular exosome|,autophagic vacuole assembly|proteolysis|proteolysis|proteolysis|,endopeptidase activity|aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|peptide binding|,10,0,0,10,-1.7,10.2,-1.6,6.89,-6.89,0.191,0,0,-3,-0.2
ENSMUSG00000021112,MPP5,"membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)",nucleus|cytoplasm|plasma membrane|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|myelin sheath adaxonal region|lateral loop|Schmidt-Lanterman incisure|protein complex|extracellular vesicular exosome|,morphogenesis of an epithelial sheet|plasma membrane organization|peripheral nervous system myelin maintenance|myelin assembly|protein localization to myelin sheath abaxonal region|nucleotide phosphorylation|establishment of protein localization to plasma membrane|,guanylate kinase activity|protein binding|protein domain specific binding|,10,0,0,10,0.9,9.39,0.9,6.87,6.87,0.192,0,0,0.1,1.9
ENSMUSG00000071519,PRSS3,"protease, serine 3",None,proteolysis|,peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.5,4.95,10,-0.4,2.25,-0.4,6.86,-6.86,0.192,0,0,-1.2,-0.1
ENSMUSG00000024286,CCNY,cyclin Y,cytoplasmic cyclin-dependent protein kinase holoenzyme complex|nucleus|plasma membrane|membrane|extracellular vesicular exosome|,regulation of cyclin-dependent protein serine/threonine kinase activity|G2/M transition of mitotic cell cycle|cell cycle|Wnt signaling pathway|positive regulation of cyclin-dependent protein serine/threonine kinase activity|cell division|regulation of canonical Wnt signaling pathway|,cyclin-dependent protein serine/threonine kinase regulator activity|protein kinase binding|,10,-0.5,5.34,10,-0.9,2.18,-0.6,6.83,-6.83,0.193,0,0,-1.5,-0.1
ENSMUSG00000079562,MAEA,macrophage erythroblast attacher,nucleus|cytoplasm|spindle|actomyosin contractile ring|cytoskeleton|plasma membrane|integral component of plasma membrane|actin cytoskeleton|membrane|nuclear matrix|,cytoskeleton organization|cell cycle|cell adhesion|negative regulation of myeloid cell apoptotic process|erythrocyte maturation|erythrocyte development|enucleate erythrocyte development|cell division|,actin binding|actin binding|,9,0.9,7.88,9,0.3,0.667,0.5,6.81,6.81,0.194,0,0,0.1,1.7
ENSMUSG00000031447,LAMP1,lysosomal-associated membrane protein 1,cytoplasm|lysosome|lysosome|endosome|late endosome|late endosome|multivesicular body|multivesicular body|vacuole|plasma membrane|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|dendrite|cytoplasmic vesicle|vesicle|sarcolemma|melanosome|neuronal cell body|cytolytic granule|phagolysosome membrane|extracellular vesicular exosome|alveolar lamellar body|,spermatogenesis|granzyme-mediated apoptotic signaling pathway|positive regulation of natural killer cell degranulation|positive regulation of natural killer cell mediated cytotoxicity|autophagic cell death|protein stabilization|establishment of protein localization to organelle|Golgi to lysosome transport|regulation of organelle transport along microtubule|,protein binding|enzyme binding|protein domain specific binding|,10,-0.8,4.41,10,-0.4,3.12,-0.5,6.79,-6.79,0.195,0,0,-1.5,-0.1
ENSMUSG00000036875,DNA2,DNA replication helicase 2 homolog (yeast),nucleus|mitochondrion|gamma DNA polymerase complex|mitochondrial nucleoid|,"DNA replication checkpoint|DNA double-strand break processing|DNA catabolic process, endonucleolytic|ATP catabolic process|DNA replication|mitochondrial DNA replication|DNA repair|base-excision repair|cellular response to DNA damage stimulus|metabolic process|DNA duplex unwinding|DNA replication, Okazaki fragment processing|DNA replication, removal of RNA primer|mitochondrial DNA repair|positive regulation of DNA replication|","nucleotide binding|DNA binding|catalytic activity|helicase activity|nuclease activity|endonuclease activity|protein binding|ATP binding|hydrolase activity|site-specific endodeoxyribonuclease activity, specific for altered base|5'-flap endonuclease activity|phosphoric ester hydrolase activity|5'-3' DNA helicase activity|single-stranded DNA-dependent ATPase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,1.2,4.67,10,0.6,4.34,0.8,6.79,6.79,0.195,0,0,-0.8,2.9
ENSMUSG00000020576,NBAS,neuroblastoma amplified sequence,membrane|,"nuclear-transcribed mRNA catabolic process|negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|",molecular_function|,9,1.1,4.21,9,1.9,3.85,1.8,6.75,6.75,0.196,0,0,0.4,3.6
ENSMUSG00000028800,HDAC1,histone deacetylase 1,histone deacetylase complex|histone deacetylase complex|chromatin|nuclear chromatin|nuclear chromatin|heterochromatin|nucleus|nucleus|nucleoplasm|transcription factor complex|transcription factor complex|cytoplasm|cytosol|Sin3 complex|NuRD complex|NuRD complex|NuRD complex|transcriptional repressor complex|neuronal cell body|protein complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein deacetylation|endoderm development|endoderm development|circadian rhythm|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|epidermal cell differentiation|positive regulation of receptor biosynthetic process|chromatin modification|histone deacetylation|hippocampus development|neuron differentiation|circadian regulation of gene expression|cellular response to oxidative stress|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|ATP-dependent chromatin remodeling|negative regulation of apoptotic process|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of neuron apoptotic process|negative regulation by host of viral transcription|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|positive regulation of oligodendrocyte differentiation|negative regulation of androgen receptor signaling pathway|hair follicle placode formation|eyelid development in camera-type eye|fungiform papilla formation|histone H3 deacetylation|histone H3 deacetylation|histone H4 deacetylation|histone H4 deacetylation|negative regulation of canonical Wnt signaling pathway|negative regulation of intrinsic apoptotic signaling pathway|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|core promoter binding|core promoter binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II transcription corepressor activity|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|histone deacetylase activity|histone deacetylase activity|protein binding|transcription factor binding|transcription factor binding|hydrolase activity|deacetylase activity|enzyme binding|histone deacetylase activity (H3-K14 specific)|nucleosomal DNA binding|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|protein complex binding|protein deacetylase activity|activating transcription factor binding|histone deacetylase activity (H4-K16 specific)|Krueppel-associated box domain binding|histone deacetylase binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,-0.3,3.14,10,-0.3,3.92,-0.3,6.74,-6.74,0.197,0,0,-0.8,0
ENSMUSG00000027748,TRPC4,"transient receptor potential cation channel, subfamily C, member 4",cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|caveola|cell-cell junction|cell surface|membrane|integral component of membrane|basolateral plasma membrane|cortical cytoskeleton|calcium channel complex|protein complex|membrane raft|,transport|ion transport|calcium ion transport|gamma-aminobutyric acid secretion|oligodendrocyte differentiation|regulation of calcium ion transport|transmembrane transport|calcium ion import|calcium ion transmembrane transport|,"ion channel activity|calcium channel activity|protein binding|beta-catenin binding|store-operated calcium channel activity|store-operated calcium channel activity|cadherin binding|inositol 1,4,5 trisphosphate binding|",9,-0.6,7.07,9,-1.4,2.18,-0.6,6.74,-6.74,0.197,0,0,-2.4,-0.1
ENSMUSG00000051695,PCBP1,poly(rC) binding protein 1,nucleus|membrane|ribonucleoprotein complex|extracellular vesicular exosome|,mRNA processing|positive regulation of translation|,DNA binding|single-stranded DNA binding|RNA binding|RNA binding|protein binding|translation activator activity|poly(A) RNA binding|,9,1.2,8.87,9,0.3,0.753,1.2,6.74,6.74,0.197,0,0,-1.1,3
ENSMUSG00000038679,TRPS1,trichorhinophalangeal syndrome I (human),nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|chondrocyte differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transmembrane receptor protein serine/threonine kinase signaling pathway|regulation of histone deacetylation|regulation of chondrocyte differentiation|negative regulation of transcription, DNA-templated|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.4,6.7,10,-0.9,0.713,-0.5,6.71,-6.71,0.198,0,0,-1.4,0
ENSMUSG00000019845,TUBE1,epsilon-tubulin 1,cytoplasm|cytoskeleton|microtubule|protein complex|,GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|GTP binding|,6,0.7,2.92,7,0.6,4.09,0.7,6.68,6.68,0.199,0,0,0.2,1.8
ENSMUSG00000033577,MYO6,myosin VI,"ruffle|intracellular|cell|nucleus|nucleoplasm|cytoplasm|cytoplasm|Golgi apparatus|plasma membrane|microvillus|coated pit|vesicle membrane|membrane|cytoplasmic membrane-bounded vesicle|myosin complex|DNA-directed RNA polymerase II, holoenzyme|endocytic vesicle|axon|cytoplasmic vesicle|filamentous actin|nuclear membrane|ruffle membrane|cell projection|neuronal cell body|intracellular membrane-bounded organelle|protein complex|apical part of cell|synapse|clathrin-coated endocytic vesicle|perinuclear region of cytoplasm|perinuclear region of cytoplasm|extracellular vesicular exosome|","protein targeting|transport|endocytosis|endocytosis|synaptic transmission|synapse assembly|sensory perception of sound|sensory perception of sound|locomotory behavior|glutamate secretion|protein transport|dendrite development|DNA damage response, signal transduction by p53 class mediator|inner ear morphogenesis|auditory receptor cell differentiation|response to drug|positive regulation of transcription from RNA polymerase II promoter|regulation of synaptic plasticity|inner ear development|regulation of secretion|cellular response to electrical stimulus|",nucleotide binding|motor activity|actin binding|protein binding|calmodulin binding|ATP binding|actin filament binding|,10,1.1,2.31,10,1.2,4.72,1.1,6.68,6.68,0.199,0,0,0.4,2
ENSMUSG00000024231,CUL2,cullin 2,nucleus|VCB complex|cullin-RING ubiquitin ligase complex|Cul2-RING ubiquitin ligase complex|,ubiquitin-dependent protein catabolic process|protein catabolic process|,protein binding|ubiquitin protein ligase binding|protein complex binding|,9,-0.4,1.5,9,-0.8,6.69,-0.6,6.64,-6.64,0.2,0,0,-1.9,0.4
ENSMUSG00000028454,PIGO,"phosphatidylinositol glycan anchor biosynthesis, class O",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|metabolic process|,"catalytic activity|protein binding|transferase activity|phosphotransferase activity, for other substituted phosphate groups|Kdo transferase activity|",10,-0.7,6.09,10,-0.3,1.97,-0.5,6.62,-6.62,0.201,0,0,-1.4,-0.1
ENSMUSG00000005410,MCM5,"minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)",nucleus|membrane|MCM complex|,DNA replication|DNA replication initiation|cell cycle|cell division|,nucleotide binding|DNA binding|DNA helicase activity|helicase activity|ATP binding|hydrolase activity|,8,0.8,2.88,8,-1.2,4.31,0.9,6.57,6.57,0.202,0,0,-1.2,2
ENSMUSG00000030682,CDIPT,CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase),endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|,lipid metabolic process|phosphatidylinositol biosynthetic process|phospholipid biosynthetic process|CDP-diacylglycerol metabolic process|,"CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity|transferase activity|phosphotransferase activity, for other substituted phosphate groups|diacylglycerol binding|manganese ion binding|carbohydrate binding|alcohol binding|",6,-1.1,3.37,6,-1.1,3.52,-1.1,6.57,-6.57,0.202,0,0,-2,0.5
ENSMUSG00000026313,HDAC4,histone deacetylase 4,histone deacetylase complex|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|cytosol|cytosol|transcriptional repressor complex|sarcomere|Z disc|neuromuscular junction|A band|actomyosin|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|skeletal system development|osteoblast development|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|protein deacetylation|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of myotube differentiation|regulation of cardiac muscle contraction by calcium ion signaling|response to denervation involved in regulation of muscle adaptation|chromatin modification|histone deacetylation|positive regulation of protein sumoylation|peptidyl-lysine deacetylation|response to drug|regulation of protein binding|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of osteoblast differentiation|negative regulation of glycolytic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of skeletal muscle fiber development|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of striated muscle cell differentiation|response to interleukin-1|histone H3 deacetylation|histone H4 deacetylation|",core promoter binding|DNA binding|transcription corepressor activity|histone deacetylase activity|protein binding|transcription factor binding|transcription factor binding|zinc ion binding|hydrolase activity|protein kinase binding|potassium ion binding|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|protein deacetylase activity|protein deacetylase activity|activating transcription factor binding|histone deacetylase activity (H4-K16 specific)|histone deacetylase binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|repressing transcription factor binding|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,-0.4,5.64,10,-0.3,1.29,-0.4,6.54,-6.54,0.203,0,0,-1.1,0
ENSMUSG00000039304,TNFSF10,"tumor necrosis factor (ligand) superfamily, member 10",extracellular space|membrane|integral component of membrane|extracellular vesicular exosome|,apoptotic process|immune response|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of release of cytochrome c from mitochondria|positive regulation of extrinsic apoptotic signaling pathway|,cytokine activity|tumor necrosis factor receptor binding|tumor necrosis factor receptor superfamily binding|,10,-0.6,4.82,10,-0.5,2.16,-0.5,6.54,-6.54,0.203,0,0,-1.3,-0.1
ENSMUSG00000020752,RECQL5,RecQ protein-like 5,"nucleus|nucleolus|cytoplasm|DNA-directed RNA polymerase II, holoenzyme|nuclear membrane|",DNA replication|DNA repair|DNA recombination|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|DNA duplex unwinding|negative regulation of transcription elongation from RNA polymerase II promoter|cell division|chromosome separation|,nucleotide binding|RNA polymerase II core binding|nucleic acid binding|DNA helicase activity|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|,10,-0.3,1.99,10,-0.4,4.85,-0.4,6.48,-6.48,0.205,0,0,-1.1,0
ENSMUSG00000033166,DIS3,DIS3 mitotic control homolog (S. cerevisiae),nuclear exosome (RNase complex)|exosome (RNase complex)|nucleus|nucleoplasm|cytoplasm|membrane|,"rRNA processing|rRNA catabolic process|positive regulation of GTPase activity|CUT catabolic process|nucleic acid phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|RNA binding|nuclease activity|endonuclease activity|exonuclease activity|5'-3' exoribonuclease activity|guanyl-nucleotide exchange factor activity|bidentate ribonuclease III activity|hydrolase activity|,8,0.6,1.31,9,0.7,5.54,0.6,6.45,6.45,0.206,0,0,0.1,1.6
ENSMUSG00000073490,AI607873,expressed sequence AI607873,nucleus|nucleolus|cytoplasm|membrane|,biological_process|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,9,0.8,6.59,9,0.4,1.23,0.7,6.4,6.4,0.208,0,0,0.1,1.5
ENSMUSG00000066516,KLK1B21,kallikrein 1-related peptidase b21,extracellular space|nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.5,7.09,10,-0.9,0.0347,-0.6,6.4,-6.4,0.208,0,0,-1.5,-0.1
ENSMUSG00000015971,ACTR8,ARP8 actin-related protein 8,nucleus|chromosome|Ino80 complex|,"DNA repair|DNA recombination|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|biological_process|cell division|",nucleotide binding|molecular_function|ATP binding|,10,1,3.93,10,-0.8,9.02,-0.7,6.32,-6.32,0.211,0,0,-2,1
ENSMUSG00000036858,PTCRA,pre T cell antigen receptor alpha,membrane|integral component of membrane|,negative regulation of thymocyte apoptotic process|,None,10,0.6,3.92,10,1.5,5.09,0.9,6.24,6.24,0.214,0,0,0.1,2.5
ENSMUSG00000028271,GTF2B,general transcription factor IIB,nucleus|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|",core promoter binding|DNA binding|protein binding|transcription factor binding|zinc ion binding|TBP-class protein binding|metal ion binding|thyroid hormone receptor binding|,8,0.6,3.28,8,0.9,3.41,0.7,6.24,6.24,0.214,0,0,0.1,2
ENSMUSG00000046994,MARS2,methionine-tRNA synthetase 2 (mitochondrial),cytoplasm|mitochondrion|mitochondrial matrix|,translation|tRNA aminoacylation for protein translation|methionyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA ligase activity|methionine-tRNA ligase activity|ATP binding|ligase activity|,4,-0.2,0.426,4,-0.9,7.09,-0.8,6.2,-6.2,0.215,0,0,-2,-0.2
ENSMUSG00000025503,TALDO1,transaldolase 1,nucleus|cytoplasm|cytosol|intracellular membrane-bounded organelle|extracellular vesicular exosome|,"carbohydrate metabolic process|fructose 6-phosphate metabolic process|pentose-phosphate shunt|pentose-phosphate shunt, non-oxidative branch|glyceraldehyde-3-phosphate metabolic process|",catalytic activity|sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity|transferase activity|carbohydrate binding|monosaccharide binding|,10,-0.3,3.44,10,-0.3,2.97,-0.3,6.11,-6.11,0.218,0,0,-1.1,0
ENSMUSG00000041415,DICER1,"dicer 1, ribonuclease type III",cytoplasm|endoplasmic reticulum-Golgi intermediate compartment|RISC complex|axon|dendrite|growth cone|,"negative regulation of transcription from RNA polymerase II promoter|meiotic spindle organization|angiogenesis|regulation of protein phosphorylation|hair follicle development|RNA processing|RNA processing|cell proliferation|regulation of Notch signaling pathway|post-embryonic development|zygote asymmetric cell division|regulation of gene expression|negative regulation of Schwann cell proliferation|positive regulation of gene expression|positive regulation of Schwann cell differentiation|rRNA catabolic process|stem cell maintenance|spinal cord motor neuron differentiation|nerve development|olfactory bulb interneuron differentiation|cerebral cortex development|lung development|embryonic limb morphogenesis|production of siRNA involved in RNA interference|production of siRNA involved in RNA interference|production of siRNA involved in RNA interference|targeting of mRNA for destruction involved in RNA interference|gene silencing by RNA|pre-miRNA processing|pre-miRNA processing|hair follicle morphogenesis|regulation of myelination|positive regulation of myelination|peripheral nervous system myelin formation|embryonic hindlimb morphogenesis|production of miRNAs involved in gene silencing by miRNA|multicellular organism growth|regulation of odontogenesis of dentin-containing tooth|regulation of viral genome replication|regulation of cell differentiation|regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|mRNA stabilization|spleen development|digestive tract development|reproductive structure development|regulation of oligodendrocyte differentiation|epidermis morphogenesis|branching morphogenesis of an epithelial tube|neuron projection morphogenesis|anatomical structure development|regulation of neurogenesis|spindle assembly|regulation of RNA metabolic process|defense response to virus|regulation of cell cycle|cardiac muscle cell development|inner ear receptor cell development|negative regulation of glial cell proliferation|intestinal epithelial cell development|regulation of enamel mineralization|hair follicle cell proliferation|RNA phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, endonucleolytic|RNA phosphodiester bond hydrolysis, endonucleolytic|regulation of miRNA metabolic process|positive regulation of miRNA metabolic process|","nucleotide binding|nucleic acid binding|RNA binding|double-stranded RNA binding|helicase activity|nuclease activity|endonuclease activity|ribonuclease III activity|ribonuclease III activity|ribonuclease III activity|protein binding|ATP binding|hydrolase activity|endoribonuclease activity, producing 5'-phosphomonoesters|miRNA binding|metal ion binding|",9,-0.2,0.507,9,1.4,9,1.3,6.11,6.11,0.218,0,0,0,3
ENSMUSG00000027454,GINS1,GINS complex subunit 1 (Psf1 homolog),nucleus|nucleus|cytoplasm|cytoplasm|,inner cell mass cell proliferation|DNA replication|,protein binding|,8,-0.8,1.08,9,0.9,7.24,0.8,6.1,6.1,0.219,0,0,0.1,1.9
ENSMUSG00000029925,TBXAS1,"thromboxane A synthase 1, platelet",endoplasmic reticulum|membrane|integral component of membrane|,prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|cellular chloride ion homeostasis|positive regulation of vasoconstriction|oxidation-reduction process|,"monooxygenase activity|thromboxane-A synthase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|isomerase activity|heme binding|metal ion binding|",10,-1.6,7.12,10,-0.7,1.1,-1.6,6.1,-6.1,0.219,0,0,-3,-0.2
ENSMUSG00000056234,NCOA4,nuclear receptor coactivator 4,mitochondrion|,biological_process|,molecular_function|,10,0.8,4.43,10,0.8,1.97,0.8,6.1,6.1,0.219,0,0,0.1,1.6
ENSMUSG00000005609,CTR9,"Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)",intracellular|nucleus|Cdc73/Paf1 complex|transcriptionally active chromatin|,"negative regulation of transcription from RNA polymerase II promoter|endodermal cell fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|JAK-STAT cascade|histone monoubiquitination|Wnt signaling pathway|stem cell maintenance|stem cell maintenance|positive regulation of transcription elongation from RNA polymerase II promoter|histone H2B ubiquitination|negative regulation of myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of histone H3-K4 methylation|positive regulation of histone H3-K4 methylation|interleukin-6-mediated signaling pathway|cellular response to lipopolysaccharide|histone H3-K4 trimethylation|histone H3-K4 trimethylation|positive regulation of histone H3-K79 methylation|",protein binding|SH2 domain binding|,7,1.1,8.31,8,-0.6,0.348,1.1,6,6,0.223,0,0,-0.6,2
ENSMUSG00000030884,UQCRC2,ubiquinol cytochrome c reductase core protein 2,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex III|mitochondrial respiratory chain complex III|membrane|extracellular vesicular exosome|respiratory chain|,proteolysis|transport|oxidation-reduction process|,catalytic activity|metalloendopeptidase activity|protein complex binding|metal ion binding|,10,-0.7,6.62,9,0.5,2.9,-0.7,5.99,-5.99,0.223,0,0,-1.8,1.4
ENSMUSG00000024130,ABCA3,"ATP-binding cassette, sub-family A (ABC1), member 3",extracellular space|plasma membrane|membrane|integral component of membrane|alveolar lamellar body|alveolar lamellar body membrane|alveolar lamellar body membrane|,transport|,nucleotide binding|ATP binding|ATPase activity|,10,0.4,0.169,10,1.6,8.01,1.6,5.82,5.82,0.23,0,0,0.2,3
ENSMUSG00000027680,FXR1,"fragile X mental retardation gene 1, autosomal homolog",nucleus|cytoplasm|cytoplasm|polysome|membrane|costamere|,multicellular organismal development|muscle organ development|negative regulation of translation|cell differentiation|,G-quadruplex RNA binding|RNA binding|mRNA 3'-UTR binding|protein binding|poly(A) RNA binding|,10,-0.6,0.323,9,1,8.67,1,5.8,5.8,0.231,0,0,0.2,2
ENSMUSG00000037731,THEMIS2,thymocyte selection associated family member 2,nucleus|cytoplasm|,immune system process|inflammatory response|T cell receptor signaling pathway|,protein binding|,10,1.5,1.21,10,0.6,5.88,1.4,5.76,5.76,0.233,0,0,0.2,2.7
ENSMUSG00000029472,ANAPC5,anaphase-promoting complex subunit 5,nucleus|anaphase-promoting complex|,cell cycle|mitotic nuclear division|cell division|protein K11-linked ubiquitination|,protein phosphatase binding|,9,1,2.25,8,-0.4,5.04,-0.4,5.74,-5.74,0.234,0,0,-1.3,1.4
ENSMUSG00000020232,HMG20B,high mobility group 20B,condensed nuclear chromosome|BRCA2-BRAF35 complex|nucleus|nucleus|chromosome|,"chromatin organization|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|chromatin modification|negative regulation of protein sumoylation|skeletal muscle cell differentiation|positive regulation of neuron differentiation|",four-way junction DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein heterodimerization activity|,10,0.6,5.32,10,0.2,1.32,0.5,5.74,5.74,0.234,0,0,0,1.4
ENSMUSG00000028821,SYF2,"SYF2 homolog, RNA splicing factor (S. cerevisiae)",nucleus|nucleus|spliceosomal complex|catalytic step 2 spliceosome|,in utero embryonic development|mRNA processing|mitotic G2 DNA damage checkpoint|gastrulation|RNA splicing|embryonic organ development|,poly(A) RNA binding|,10,1.4,3.53,10,0.6,3.68,0.7,5.71,5.71,0.235,0,0,0.1,2.3
ENSMUSG00000021918,NEK4,NIMA (never in mitosis gene a)-related expressed kinase 4,nucleus|,protein phosphorylation|cell cycle|mitotic nuclear division|phosphorylation|signal transduction by phosphorylation|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.4,3.69,10,1.4,4.24,0.7,5.71,5.71,0.235,0,0,0,2.4
ENSMUSG00000028307,ALDOB,"aldolase B, fructose-bisphosphate",nucleus|cytoplasm|lysosome|microtubule organizing center|cytosol|cytoskeleton|plasma membrane|rough endoplasmic reticulum membrane|smooth endoplasmic reticulum membrane|centriolar satellite|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|extracellular vesicular exosome|,"fructose metabolic process|glycolytic process|NADH oxidation|response to zinc ion|fructose 1,6-bisphosphate metabolic process|positive regulation of ATPase activity|response to peptide hormone|vacuolar proton-transporting V-type ATPase complex assembly|",catalytic activity|fructose-bisphosphate aldolase activity|fructose-bisphosphate aldolase activity|cytoskeletal protein binding|lyase activity|phosphatidylcholine binding|identical protein binding|ATPase binding|fructose binding|,10,0.5,1.04,10,1.7,7.61,1.7,5.71,5.71,0.235,0,0,0.3,3
ENSMUSG00000020923,UBTF,"upstream binding transcription factor, RNA polymerase I",fibrillar center|nucleus|nucleolus|nucleolus|,"chromatin silencing at rDNA|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription elongation from RNA polymerase I promoter|positive regulation of transcription from RNA polymerase I promoter|",DNA binding|protein binding|poly(A) RNA binding|,9,-1.1,7.66,8,0.2,0.921,-1.1,5.68,-5.68,0.236,0,0,-2,0.9
ENSMUSG00000051786,TUBGCP6,"tubulin, gamma complex associated protein 6",centrosome|gamma-tubulin ring complex|membrane|extracellular vesicular exosome|,microtubule nucleation|,microtubule binding|,10,-0.9,7.8,10,-0.2,0.622,-0.9,5.67,-5.67,0.237,0,0,-1.8,-0.1
ENSMUSG00000030695,ALDOA,"aldolase A, fructose-bisphosphate",extracellular space|nucleus|cytoplasm|mitochondrion|actin cytoskeleton|membrane|sperm fibrous sheath|extracellular vesicular exosome|,"fructose metabolic process|glycolytic process|ATP biosynthetic process|striated muscle contraction|regulation of cell shape|fructose 1,6-bisphosphate metabolic process|muscle cell cellular homeostasis|",fructose-bisphosphate aldolase activity|fructose-bisphosphate aldolase activity|cytoskeletal protein binding|poly(A) RNA binding|fructose binding|,7,-0.5,2.49,7,-0.8,3.76,-0.6,5.65,-5.65,0.238,0,0,-1.8,0
ENSMUSG00000021639,GTF2H2,"general transcription factor II H, polypeptide 2",core TFIIH complex|nucleus|holo TFIIH complex|,"G-protein coupled receptor internalization|ATP catabolic process|DNA repair|nucleotide-excision repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|cellular response to DNA damage stimulus|",protein kinase activity|DNA-dependent ATPase activity|zinc ion binding|RNA polymerase II carboxy-terminal domain kinase activity|metal ion binding|protein N-terminus binding|,10,0.7,4.77,9,0.5,1.48,0.6,5.65,5.65,0.238,0,0,-0.8,1.5
ENSMUSG00000029910,MAD2L1,MAD2 mitotic arrest deficient-like 1,"chromosome, centromeric region|kinetochore|kinetochore|kinetochore|spindle pole|nucleus|nuclear pore|chromosome|cytoplasm|cytosol|cytoskeleton|perinuclear region of cytoplasm|mitotic spindle|",mitotic sister chromatid segregation|cell cycle|mitotic nuclear division|mitotic cell cycle checkpoint|mitotic spindle assembly checkpoint|mitotic spindle assembly checkpoint|negative regulation of protein catabolic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of mitotic metaphase/anaphase transition|negative regulation of mitotic cell cycle|cell division|negative regulation of mitotic anaphase-promoting complex activity|positive regulation of mitotic cell cycle spindle assembly checkpoint|positive regulation of mitotic cell cycle spindle assembly checkpoint|,protein binding|identical protein binding|protein homodimerization activity|,6,0.9,4.78,6,2.1,3.73,2,5.65,5.65,0.238,0,0,0.5,3.9
ENSMUSG00000039187,FANCI,"Fanconi anemia, complementation group I",nucleus|membrane|Fanconi anaemia nuclear complex|,DNA repair|cellular response to DNA damage stimulus|cell cycle|positive regulation of protein ubiquitination|positive regulation of protein ubiquitination|,DNA polymerase binding|,10,-1.1,4.36,10,-0.8,1.99,-0.9,5.64,-5.64,0.238,0,0,-1.9,-0.2
ENSMUSG00000036712,CYLD,cylindromatosis (turban tumor syndrome),nucleus|cytoplasm|centrosome|cytosol|cytosol|cytoskeleton|microtubule|cytoplasmic microtubule|plasma membrane|membrane|midbody|extrinsic component of cytoplasmic side of plasma membrane|,proteolysis|ubiquitin-dependent protein catabolic process|regulation of mitotic cell cycle|regulation of mitotic cell cycle|Wnt signaling pathway|protein deubiquitination|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB import into nucleus|negative regulation of T cell differentiation|necroptotic process|regulation of microtubule cytoskeleton organization|protein K63-linked deubiquitination|protein K63-linked deubiquitination|negative regulation of canonical Wnt signaling pathway|ripoptosome assembly involved in necroptotic process|positive regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway|,ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|protein kinase binding|ubiquitinyl hydrolase activity|metal ion binding|Lys63-specific deubiquitinase activity|Lys63-specific deubiquitinase activity|proline-rich region binding|,10,-0.4,4.3,10,-0.3,1.73,-0.3,5.63,-5.63,0.238,0,0,-1.1,0.1
ENSMUSG00000006386,TEK,endothelial-specific receptor tyrosine kinase,stress fiber|extracellular region|cytoplasm|cytoskeleton|actin filament|plasma membrane|integral component of plasma membrane|microvillus|cell-cell junction|basal plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|cell junction|membrane raft|,angiogenesis|angiogenesis|patterning of blood vessels|vasculogenesis|positive regulation of protein phosphorylation|endothelial cell proliferation|regulation of endothelial cell proliferation|sprouting angiogenesis|protein phosphorylation|cell-matrix adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|heart development|positive regulation of endothelial cell migration|positive regulation of endothelial cell migration|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|single organismal cell-cell adhesion|negative regulation of angiogenesis|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|hemopoiesis|regulation of cell migration|positive regulation of vascular endothelial growth factor receptor signaling pathway|response to retinoic acid|regulation of establishment or maintenance of cell polarity|positive regulation of peptidyl-serine phosphorylation|substrate adhesion-dependent cell spreading|intracellular signal transduction|negative regulation of apoptotic process|positive regulation of phosphatidylinositol 3-kinase activity|response to estrogen|regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of cell adhesion|protein autophosphorylation|Tie signaling pathway|Tie signaling pathway|protein oligomerization|positive regulation of focal adhesion assembly|positive regulation of protein kinase B signaling|heart trabecula formation|positive regulation of ERK1 and ERK2 cascade|positive regulation of intracellular signal transduction|positive regulation of actin cytoskeleton reorganization|negative regulation of endothelial cell apoptotic process|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|",10,-0.8,2.97,10,-0.7,2.96,-0.8,5.61,-5.61,0.239,0,0,-1.9,0
ENSMUSG00000022636,ALCAM,activated leukocyte cell adhesion molecule,external side of plasma membrane|membrane|integral component of membrane|axon|neuronal cell body|extracellular vesicular exosome|,cell adhesion|axon guidance|motor neuron axon guidance|,protein binding|,10,-0.4,4.37,10,-0.3,1.58,-0.4,5.58,-5.58,0.241,0,0,-1.5,0.2
ENSMUSG00000033952,ASPM,"asp (abnormal spindle)-like, microcephaly associated (Drosophila)",spindle pole|nucleus|cytoplasm|cytoskeleton|midbody|,neuron migration|neuron migration|positive regulation of neuroblast proliferation|positive regulation of neuroblast proliferation|cell cycle|mitotic nuclear division|spermatogenesis|brain development|forebrain neuroblast division|negative regulation of neuron differentiation|negative regulation of asymmetric cell division|oogenesis|developmental growth|cell division|maintenance of centrosome location|positive regulation of canonical Wnt signaling pathway|,molecular_function|calmodulin binding|,10,0.3,1.02,10,1.5,7.32,0.6,5.58,5.58,0.241,0,0,0.1,2.7
ENSMUSG00000041763,TPP2,tripeptidyl peptidase II,nucleus|cytoplasm|,proteolysis|proteolysis|,aminopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|tripeptidyl-peptidase activity|hydrolase activity|peptide binding|,10,0.7,2.7,10,1.3,3.59,0.7,5.57,5.57,0.241,0,0,0.2,1.9
ENSMUSG00000057130,TXNL4A,thioredoxin-like 4A,nucleus|U5 snRNP|U5 snRNP|cytoplasm|,biological_process|,molecular_function|,6,0.8,4.98,5,0.4,1.59,0.7,5.55,5.55,0.242,0,0,0.1,1.9
ENSMUSG00000029438,BCL7A,B cell CLL/lymphoma 7A,cellular_component|,biological_process|,molecular_function|,10,-0.7,0.768,10,1,6.13,0.8,5.53,5.53,0.243,0,0,-0.5,2
ENSMUSG00000021707,DHFR,dihydrofolate reductase,None,glycine biosynthetic process|one-carbon metabolic process|nucleotide biosynthetic process|response to methotrexate|dihydrofolate metabolic process|tetrahydrofolate metabolic process|tetrahydrofolate biosynthetic process|oxidation-reduction process|,RNA binding|mRNA binding|dihydrofolate reductase activity|dihydrofolate reductase activity|drug binding|oxidoreductase activity|NADP binding|dihydrofolic acid binding|,6,0.6,1.59,6,1.3,5.61,1.2,5.47,5.47,0.245,0,0,0.3,2
ENSMUSG00000005686,AMPD3,adenosine monophosphate deaminase 3,cellular_component|,IMP biosynthetic process|IMP biosynthetic process|nucleotide metabolic process|purine ribonucleoside monophosphate biosynthetic process|IMP salvage|ADP metabolic process|AMP metabolic process|ATP metabolic process|energy homeostasis|,AMP deaminase activity|AMP deaminase activity|AMP deaminase activity|hydrolase activity|deaminase activity|metal ion binding|,10,0,0,10,-0.7,8.17,-0.6,5.46,-5.46,0.246,0,0,-1.7,-0.1
ENSMUSG00000021258,CCNK,cyclin K,cyclin K-CDK12 complex|cyclin K-CDK13 complex|nucleus|,"regulation of cyclin-dependent protein serine/threonine kinase activity|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|cell division|negative regulation of cell cycle arrest|",cyclin-dependent protein serine/threonine kinase activity|RNA polymerase II carboxy-terminal domain kinase activity|protein kinase binding|,6,-1.6,8,5,0.3,1.02,-1.6,5.45,-5.45,0.246,0,0,-3,-0.1
ENSMUSG00000051257,TRAP1A,tumor rejection antigen P1A,nucleus|,None,None,10,0.7,4.38,10,0.4,1.43,0.7,5.44,5.44,0.247,0,0,-0.1,1.7
ENSMUSG00000027951,ADAR,"adenosine deaminase, RNA-specific",nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|membrane|supraspliceosomal complex|,"in utero embryonic development|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|adenosine to inosine editing|adenosine to inosine editing|RNA processing|mRNA processing|protein import into nucleus|protein export from nucleus|response to virus|base conversion or substitution editing|gene silencing by RNA|response to interferon-alpha|negative regulation of apoptotic process|negative regulation of protein kinase activity by regulation of protein phosphorylation|negative regulation of protein kinase activity by regulation of protein phosphorylation|positive regulation of viral genome replication|positive regulation of viral genome replication|negative regulation of viral genome replication|innate immune response|defense response to virus|",DNA binding|left-handed Z-DNA binding|RNA binding|double-stranded RNA binding|double-stranded RNA adenosine deaminase activity|double-stranded RNA adenosine deaminase activity|adenosine deaminase activity|protein binding|hydrolase activity|poly(A) RNA binding|metal ion binding|,5,-1.5,3.94,5,-1,2.64,-1.5,5.44,-5.44,0.247,0,0,-3,-0.4
ENSMUSG00000056612,PPP1R14B,"protein phosphatase 1, regulatory (inhibitor) subunit 14B",cytoplasm|,regulation of phosphorylation|negative regulation of catalytic activity|regulation of catalytic activity|,protein phosphatase inhibitor activity|protein phosphatase type 1 regulator activity|phosphatase inhibitor activity|,9,0.3,1.63,9,1.1,6.12,0.8,5.41,5.41,0.248,0,0,0.2,1.9
ENSMUSG00000023110,PRMT5,protein arginine N-methyltransferase 5,nucleus|nucleus|cytoplasm|cytosol|cytosol|methylosome|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|spliceosomal snRNP assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|protein methylation|chromatin modification|peptidyl-arginine methylation|peptidyl-arginine methylation, to symmetrical-dimethyl arginine|peptidyl-arginine methylation, to symmetrical-dimethyl arginine|methylation|circadian regulation of gene expression|histone arginine methylation|peptidyl-arginine N-methylation|endothelial cell activation|histone H4-R3 methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|core promoter sequence-specific DNA binding|chromatin binding|transcription corepressor activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N symmetric methyltransferase activity|ribonucleoprotein complex binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",6,0.6,1.24,6,0.6,4.44,0.6,5.41,5.41,0.248,0,0,-1.3,1.8
ENSMUSG00000042104,UGGT2,UDP-glucose glycoprotein glucosyltransferase 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.9,7.91,0.9,5.41,5.41,0.248,0,0,0.1,1.8
ENSMUSG00000057667,BLOC1S3,"biogenesis of lysosomal organelles complex-1, subunit 3",intracellular|cell|cytoplasm|cytosol|transport vesicle|BLOC-1 complex|BLOC-1 complex|,eye development|blood coagulation|anterograde axon cargo transport|platelet activation|neuron projection development|melanosome transport|melanosome organization|positive regulation of natural killer cell activation|secretion of lysosomal enzymes|endosome to melanosome transport|response to drug|pigmentation|pigmentation|developmental pigmentation|anterograde synaptic vesicle transport|platelet dense granule organization|,protein binding|,10,0.4,1.73,10,0.5,4.02,0.4,5.39,5.39,0.249,0,0,-0.1,1.3
ENSMUSG00000044338,APLNR,apelin receptor,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|multicellular organismal development|gastrulation|regulation of body fluid levels|,signal transducer activity|G-protein coupled receptor activity|,10,0.8,1,10,1,4.71,0.9,5.38,5.38,0.25,0,0,0.2,1.9
ENSMUSG00000031207,MSN,moesin,uropod|extracellular space|cytoplasm|cytoskeleton|plasma membrane|microvillus|focal adhesion|cytoplasmic side of plasma membrane|cell surface|membrane|basolateral plasma membrane|apical plasma membrane|extrinsic component of membrane|filopodium|T-tubule|secretory granule membrane|filopodium membrane|cell projection|apical part of cell|apical part of cell|cell tip|extracellular vesicular exosome|blood microparticle|,positive regulation of gene expression|establishment of endothelial barrier|regulation of lymphocyte migration|,double-stranded RNA binding|actin binding|receptor binding|cytoskeletal protein binding|protein kinase binding|cell adhesion molecule binding|,10,-0.3,3.35,10,-0.7,3.19,-0.5,5.38,-5.38,0.25,0,0,-1.4,0
ENSMUSG00000022432,SMC1B,structural maintenance of chromosomes 1B,"chromosome, centromeric region|condensed nuclear chromosome|synaptonemal complex|lateral element|nucleus|chromosome|meiotic cohesin complex|meiotic cohesin complex|nuclear meiotic cohesin complex|",cell cycle|sister chromatid cohesion|meiotic nuclear division|chromosome organization|,nucleotide binding|DNA binding|protein binding|ATP binding|,10,0.8,3.68,10,1.3,2.81,0.8,5.33,5.33,0.252,0,0,-0.3,2
ENSMUSG00000071649,B3GAT3,"beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)",Golgi apparatus|cis-Golgi network|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,heparan sulfate proteoglycan biosynthetic process|chondroitin sulfate proteoglycan biosynthetic process|dermatan sulfate proteoglycan biosynthetic process|,galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity|glucuronosyltransferase activity|transferase activity|metal ion binding|,10,0.6,3.21,10,0.4,2.57,0.4,5.31,5.31,0.252,0,0,0,1.6
ENSMUSG00000021359,TFAP2A,"transcription factor AP-2, alpha",nucleus|nucleus|transcription factor complex|cytoplasm|Golgi apparatus|centrosome|cytosol|intracellular membrane-bounded organelle|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|kidney development|neural tube closure|lens morphogenesis in camera-type eye|outflow tract morphogenesis|keratinocyte development|optic vesicle morphogenesis|optic cup structural organization|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|sensory perception of sound|negative regulation of cell proliferation|negative regulation of cell proliferation|embryonic pattern specification|embryonic body morphogenesis|positive regulation of gene expression|negative regulation of transcription by competitive promoter binding|neural crest cell development|anterior neuropore closure|trigeminal nerve development|oculomotor nerve formation|forebrain neuron development|positive regulation of cell migration|positive regulation of bone mineralization|response to lipopolysaccharide|embryonic forelimb morphogenesis|forelimb morphogenesis|negative regulation of epidermal growth factor receptor signaling pathway|inner ear morphogenesis|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|skin development|regulation of cell differentiation|regulation of neuron differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|sympathetic nervous system development|embryonic camera-type eye morphogenesis|embryonic cranial skeleton morphogenesis|skeletal system morphogenesis|epidermis morphogenesis|palate development|lens induction in camera-type eye|face morphogenesis|bone morphogenesis|eyelid development in camera-type eye|cornea development in camera-type eye|positive regulation of tooth mineralization|cellular response to iron ion|basement membrane organization|negative regulation of reactive oxygen species metabolic process|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|core promoter proximal region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription corepressor activity|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription coactivator activity|protein binding|transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein dimerization activity|,10,-1,7.82,10,1.5,3.02,-1,5.26,-5.26,0.255,0,0,-2,2.5
ENSMUSG00000017716,BIRC5,baculoviral IAP repeat-containing 5,"nuclear chromosome|chromosome, centromeric region|kinetochore|condensed chromosome kinetochore|nucleus|chromosome|cytoplasm|cytoplasm|centriole|cytosol|cytoskeleton|microtubule|spindle microtubule|cytoplasmic microtubule|apical plasma membrane|midbody|interphase microtubule organizing center|chromosome passenger complex|","G2/M transition of mitotic cell cycle|microtubule cytoskeleton organization|cytokinesis|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|cell cycle|chromosome segregation|mitotic nuclear division|regulation of mitotic cell cycle|embryo development|negative regulation of peptidase activity|protein complex localization|positive regulation of exit from mitosis|spindle checkpoint|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of neuron apoptotic process|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of mitotic cell cycle|cell division|establishment of chromosome localization|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of type B pancreatic cell proliferation|",cysteine-type endopeptidase inhibitor activity|protein binding|microtubule binding|zinc ion binding|Ran GTPase binding|tubulin binding|enzyme binding|peptidase inhibitor activity|identical protein binding|protein homodimerization activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|metal ion binding|protein heterodimerization activity|cofactor binding|chaperone binding|,4,1,5.37,5,-0.9,6.42,-0.8,5.26,-5.26,0.255,0,0,-2,1.6
ENSMUSG00000053754,CHD8,chromodomain helicase DNA binding protein 8,nucleus|nucleus|protein complex|MLL1 complex|,"in utero embryonic development|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|Wnt signaling pathway|chromatin modification|negative regulation of Wnt signaling pathway|DNA duplex unwinding|ATP-dependent chromatin remodeling|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase III promoter|canonical Wnt signaling pathway|negative regulation of fibroblast apoptotic process|","nucleotide binding|p53 binding|DNA binding|DNA binding|DNA helicase activity|helicase activity|protein binding|ATP binding|beta-catenin binding|DNA-dependent ATPase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides|methylated histone binding|histone binding|armadillo repeat domain binding|",9,-1.4,8.46,9,0,0,-1.4,5.22,-5.22,0.257,0,0,-3,0.3
ENSMUSG00000050732,VAMP8,vesicle-associated membrane protein 8,mitochondrion|lysosome|lysosomal membrane|endosome|early endosome|cell surface|membrane|integral component of membrane|secretory granule|SNARE complex|late endosome membrane|recycling endosome|extracellular vesicular exosome|,autophagic vacuole fusion|protein complex assembly|transport|vesicle fusion|autophagy|protein transport|vesicle-mediated transport|regulation of endocytosis|SNARE complex assembly|viral entry into host cell|membrane fusion|,SNAP receptor activity|protein binding|syntaxin binding|,10,0.2,0.282,10,0.7,5.51,0.6,5.22,5.22,0.257,0,0,0,1.4
ENSMUSG00000019471,CDC37,cell division cycle 37,cytoplasm|cytosol|ruffle membrane|protein complex|extracellular vesicular exosome|,regulation of interferon-gamma-mediated signaling pathway|regulation of type I interferon-mediated signaling pathway|,protein kinase binding|heat shock protein binding|mitogen-activated protein kinase kinase kinase binding|protein kinase B binding|chaperone binding|Hsp90 protein binding|,6,1,6.92,7,-0.7,2.73,0.9,5.21,5.21,0.257,0,0,-0.7,2
ENSMUSG00000035944,TTC38,tetratricopeptide repeat domain 38,cellular_component|,biological_process|,molecular_function|,10,1.2,4.75,10,0.3,2.54,0.3,5.19,5.19,0.258,0,0,-1.3,2.5
ENSMUSG00000045680,TCF21,transcription factor 21,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|ureteric bud development|branching involved in ureteric bud morphogenesis|morphogenesis of a branching structure|kidney development|vasculature development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|sex determination|sex differentiation|organ morphogenesis|branchiomeric skeletal muscle development|epithelial cell differentiation|regulation of histone deacetylation|glomerulus development|positive regulation of transcription from RNA polymerase II promoter|lung alveolus development|spleen development|embryonic digestive tract morphogenesis|reproductive structure development|gland development|Sertoli cell differentiation|palate development|lung morphogenesis|lung vasculature development|bronchiole development|diaphragm development|respiratory system development|negative regulation of androgen receptor signaling pathway|metanephric mesenchymal cell differentiation|metanephric glomerular capillary formation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|protein binding|histone deacetylase binding|bHLH transcription factor binding|protein dimerization activity|androgen receptor binding|E-box binding|,10,0.3,0.823,10,1.6,7.59,1.6,5.17,5.17,0.259,0,0,0.2,3
ENSMUSG00000061132,BLNK,B cell linker,intracellular|cytoplasm|plasma membrane|membrane|,positive regulation of signal transduction|intracellular signal transduction|B cell activation|,SH3/SH2 adaptor activity|protein binding|,10,0.3,3.62,10,0.4,2.02,0.3,5.16,5.16,0.26,0,0,-0.1,1.1
ENSMUSG00000070385,AMPD1,adenosine monophosphate deaminase 1,cellular_component|,nucleotide metabolic process|purine ribonucleoside monophosphate biosynthetic process|response to organic substance|IMP salvage|,AMP deaminase activity|hydrolase activity|deaminase activity|myosin heavy chain binding|metal ion binding|,10,-0.5,3.33,10,-0.3,2.23,-0.4,5.15,-5.15,0.26,0,0,-1.3,0.4
ENSMUSG00000027263,TUBGCP4,"tubulin, gamma complex associated protein 4",spindle pole|cytoplasm|centrosome|microtubule organizing center|cytoskeleton|microtubule|membrane|,microtubule cytoskeleton organization|biological_process|,molecular_function|,8,-0.5,2.65,7,0.4,3.44,-0.6,5.1,-5.1,0.263,0,0,-1.4,1.6
ENSMUSG00000028936,RPL22,ribosomal protein L22,intracellular|nucleus|cytoplasm|ribosome|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|alpha-beta T cell differentiation|,RNA binding|structural constituent of ribosome|heparin binding|poly(A) RNA binding|,10,0.3,1.32,10,0.5,4.09,0.4,5.04,5.04,0.266,0,0,-0.2,1.3
ENSMUSG00000022545,ERCC4,"excision repair cross-complementing rodent repair deficiency, complementation group 4","nucleotide-excision repair complex|nucleotide-excision repair factor 1 complex|nucleotide-excision repair factor 1 complex|chromosome, telomeric region|nuclear chromosome, telomeric region|nucleus|transcription factor TFIID complex|","resolution of meiotic recombination intermediates|telomere maintenance|double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|DNA metabolic process|DNA repair|DNA repair|nucleotide-excision repair|nucleotide-excision repair, DNA incision, 3'-to lesion|nucleotide-excision repair, DNA incision, 5'-to lesion|nucleotide-excision repair, DNA incision, 5'-to lesion|cellular response to DNA damage stimulus|response to UV|UV protection|telomere maintenance via telomere shortening|negative regulation of telomere maintenance|nucleotide-excision repair, DNA incision|nucleotide-excision repair involved in interstrand cross-link repair|",single-stranded DNA endodeoxyribonuclease activity|TFIID-class transcription factor binding|nucleic acid binding|DNA binding|damaged DNA binding|damaged DNA binding|single-stranded DNA binding|single-stranded DNA binding|nuclease activity|endonuclease activity|endodeoxyribonuclease activity|endodeoxyribonuclease activity|protein binding|protein C-terminus binding|hydrolase activity|phosphoric ester hydrolase activity|structure-specific DNA binding|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|protein N-terminus binding|,10,0.7,2.62,10,0.5,3.04,0.5,5.03,5.03,0.266,0,0,-0.1,1.5
ENSMUSG00000042489,CLSPN,claspin,nucleus|chromosome|,DNA replication checkpoint|DNA damage checkpoint|DNA repair|cellular response to DNA damage stimulus|cell cycle|peptidyl-serine phosphorylation|G2 DNA damage checkpoint|activation of protein kinase activity|mitotic DNA replication checkpoint|,DNA secondary structure binding|DNA binding|anaphase-promoting complex binding|,10,-1.2,0.498,10,-0.5,6.66,-0.5,5.03,-5.03,0.266,0,0,-1.7,0
ENSMUSG00000023949,TCTE1,t-complex-associated testis expressed 1,cellular_component|,biological_process|,molecular_function|,10,-1.3,4.97,10,-0.7,2.05,-1.3,5.03,-5.03,0.266,0,0,-2,-0.1
ENSMUSG00000029234,TMEM165,transmembrane protein 165,lysosome|lysosomal membrane|endosome|Golgi apparatus|endosome membrane|membrane|integral component of membrane|trans-Golgi network membrane|intracellular membrane-bounded organelle|,protein N-linked glycosylation|cellular calcium ion homeostasis|Golgi calcium ion transport|regulation of lysosomal lumen pH|,molecular_function|,9,0.5,3.23,9,0.4,2.1,0.5,4.98,4.98,0.269,0,0,-0.9,1.5
ENSMUSG00000059586,NSMCE2,"non-SMC element 2 homolog (MMS21, S. cerevisiae)","chromosome, telomeric region|nucleus|chromosome|PML body|Smc5-Smc6 complex|",telomere maintenance via recombination|double-strand break repair via homologous recombination|DNA repair|DNA recombination|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|positive regulation of maintenance of mitotic sister chromatid cohesion|positive regulation of mitotic metaphase/anaphase transition|cell division|cellular senescence|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,0.3,3.02,9,0.6,2.64,0.5,4.98,4.98,0.269,0,0,0,1.4
ENSMUSG00000028041,ADAM15,a disintegrin and metallopeptidase domain 15 (metargidin),membrane|integral component of membrane|cell junction|cytoplasmic vesicle|cell projection|,angiogenesis|proteolysis|cell adhesion|collagen catabolic process|cardiac epithelial to mesenchymal transition|,metalloendopeptidase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|SH3 domain binding|metal ion binding|,10,-0.3,2.33,9,-0.5,2.92,-0.4,4.96,-4.96,0.27,0,0,-1.3,0.2
ENSMUSG00000027342,PCNA,proliferating cell nuclear antigen,cyclin-dependent protein kinase holoenzyme complex|intracellular|nucleus|nucleus|nucleus|nuclear lamina|replication fork|cytoplasm|centrosome|nuclear replication fork|PCNA complex|extracellular vesicular exosome|PCNA-p21 complex|,"negative regulation of transcription from RNA polymerase II promoter|DNA replication|leading strand elongation|regulation of DNA replication|DNA repair|base-excision repair, gap-filling|mismatch repair|mismatch repair|cellular response to DNA damage stimulus|translesion synthesis|positive regulation of deoxyribonuclease activity|response to lipid|",purine-specific mismatch base pair DNA N-glycosylase activity|DNA binding|protein binding|transcription factor binding|DNA polymerase processivity factor activity|receptor tyrosine kinase binding|dinucleotide insertion or deletion binding|MutLalpha complex binding|identical protein binding|DNA polymerase binding|,1,1.7,6.3,2,-0.1,0.0363,1.7,4.95,4.95,0.27,0,0,-0.2,3
ENSMUSG00000027162,LIN7C,lin-7 homolog C (C. elegans),cell|cytoplasm|plasma membrane|cell-cell junction|tight junction|membrane|cell junction|neuron projection|synapse|synapse|postsynaptic membrane|extracellular vesicular exosome|MPP7-DLG1-LIN7 complex|,morphogenesis of an epithelial sheet|transport|exocytosis|neurotransmitter secretion|protein transport|,protein binding|cytoskeletal protein binding|protein domain specific binding|PDZ domain binding|L27 domain binding|,10,0.2,0.765,10,1.6,7.64,1.6,4.93,4.93,0.271,0,0,0.2,3
ENSMUSG00000005871,APC,adenomatosis polyposis coli,kinetochore|nucleus|nucleus|cytoplasm|cytoplasm|centrosome|cytoskeleton|microtubule|cytoplasmic microtubule|plasma membrane|plasma membrane|cell-cell adherens junction|tight junction|cell cortex|membrane|lateral plasma membrane|lamellipodium|cell junction|axon|dendrite|growth cone|growth cone|beta-catenin destruction complex|cell projection membrane|nuclear membrane|ruffle membrane|Scrib-APC-beta-catenin complex|microtubule plus-end|cell projection|neuron projection|neuronal cell body|protein complex|axonal growth cone|axonal growth cone|neuron projection terminus|synapse|cell body fiber|,mitotic cytokinesis|mitotic cytokinesis|kidney development|hair follicle development|protein complex assembly|cellular response to DNA damage stimulus|negative regulation of microtubule depolymerization|negative regulation of microtubule depolymerization|cell cycle arrest|metaphase/anaphase transition of mitotic cell cycle|metaphase/anaphase transition of mitotic cell cycle|mitotic spindle assembly checkpoint|establishment or maintenance of cell polarity|pattern specification process|axonogenesis|axonogenesis|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|axis specification|anterior/posterior pattern specification|dorsal/ventral pattern formation|proximal/distal pattern formation|Wnt signaling pathway|Wnt signaling pathway|cell migration|cell migration|stem cell maintenance|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|regulation of cell migration|regulation of cell migration|positive regulation of cell migration|positive regulation of cell migration|regulation of epithelial cell differentiation|positive regulation of epithelial cell differentiation|positive regulation of microtubule polymerization|cytoplasmic microtubule organization|neuron projection development|positive regulation of pseudopodium assembly|regulation of microtubule-based process|T cell differentiation in thymus|somatic stem cell maintenance|somatic stem cell maintenance|negative regulation of odontogenesis|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of MAPK cascade|negative regulation of MAPK cascade|skin development|canonical Wnt signaling pathway involved in negative regulation of apoptotic process|canonical Wnt signaling pathway involved in positive regulation of apoptotic process|regulation of cell differentiation|positive regulation of cell differentiation|regulation of osteoblast differentiation|regulation of osteoclast differentiation|positive regulation of protein catabolic process|positive regulation of protein catabolic process|negative regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of cell adhesion|muscle cell cellular homeostasis|thymus development|negative regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|regulation of nitrogen compound metabolic process|chromosome organization|chromosome organization|regulation of cell cycle|positive regulation of cell division|regulation of attachment of spindle microtubules to kinetochore|regulation of attachment of spindle microtubules to kinetochore|retina development in camera-type eye|canonical Wnt signaling pathway|negative regulation of epithelial cell proliferation involved in prostate gland development|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|regulation of glutamate metabolic process|,protease binding|protein binding|beta-catenin binding|beta-catenin binding|beta-catenin binding|microtubule binding|protein kinase regulator activity|protein kinase binding|protein complex binding|gamma-catenin binding|microtubule plus-end binding|microtubule plus-end binding|,10,-0.4,3.93,10,-0.3,1.41,-0.4,4.92,-4.92,0.272,0,0,-1.2,0.2
ENSMUSG00000029204,RHOH,"ras homolog gene family, member H",immunological synapse|intracellular|cytoplasm|cytoplasm|plasma membrane|membrane|,small GTPase mediated signal transduction|T cell differentiation|negative regulation of phosphorylation|negative regulation of catalytic activity|negative regulation of I-kappaB kinase/NF-kappaB signaling|mast cell activation|,nucleotide binding|protein binding|GTP binding|kinase inhibitor activity|,10,2,7.39,10,0.3,0.561,0.3,4.91,4.91,0.272,0,0,0.1,3.8
ENSMUSG00000031386,HCFC1,host cell factor C1,histone acetyltransferase complex|nucleus|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|cytoplasm|cytoplasm|mitochondrion|membrane|neuronal cell body|Set1C/COMPASS complex|SAGA-type complex|MLL5-L complex|MLL1 complex|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell cycle|positive regulation of gene expression|chromatin modification|release from viral latency|regulation of protein complex assembly|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|positive regulation of transcription from RNA polymerase II promoter|protein stabilization|regulation of RNA biosynthetic process|",RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|chromatin binding|transcription coactivator activity|transcription coactivator activity|protein binding|identical protein binding|histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|histone acetyltransferase activity (H4-K16 specific)|,8,-0.7,3.97,8,2,2.19,-0.9,4.86,-4.86,0.275,0,0,-2,2.5
ENSMUSG00000076439,MOG,myelin oligodendrocyte glycoprotein,membrane|integral component of membrane|,cell adhesion|positive regulation of MyD88-dependent toll-like receptor signaling pathway|,None,10,0,0,10,0.7,5.22,0.7,4.85,4.85,0.276,0,0,-0.2,1.7
ENSMUSG00000036594,H2-AA,"histocompatibility 2, class II antigen A, alpha",lysosome|plasma membrane|external side of plasma membrane|membrane|membrane|integral component of membrane|MHC class II protein complex|,immune system process|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|immune response|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|response to interferon-gamma|negative regulation of T cell proliferation|positive regulation of T cell differentiation|antigen processing and presentation of peptide antigen|,protein binding|peptide antigen binding|protein heterodimerization activity|,10,-0.9,4.38,10,-1.2,1.3,-1,4.81,-4.81,0.278,0,0,-2,-0.1
ENSMUSG00000056394,LIG1,"ligase I, DNA, ATP-dependent",nucleus|nucleus|nucleus|chromosome|mitochondrion|Golgi apparatus|intracellular membrane-bounded organelle|,DNA replication|DNA ligation|DNA ligation|lagging strand elongation|DNA repair|double-strand break repair via nonhomologous end joining|DNA recombination|cellular response to DNA damage stimulus|cell cycle|response to hydrogen peroxide|DNA ligation involved in DNA repair|cell division|DNA biosynthetic process|,nucleotide binding|DNA binding|DNA ligase activity|DNA ligase (ATP) activity|ATP binding|ligase activity|metal ion binding|,10,-0.6,3.97,10,-0.3,1.53,-0.5,4.81,-4.81,0.278,0,0,-1.7,0.3
ENSMUSG00000027048,ABCB11,"ATP-binding cassette, sub-family B (MDR/TAP), member 11",Golgi membrane|Golgi apparatus|plasma membrane|membrane|integral component of membrane|apical plasma membrane|apical part of cell|intercellular canaliculus|extracellular vesicular exosome|,ATP catabolic process|transport|drug transmembrane transport|lipid transport|canalicular bile acid transport|canalicular bile acid transport|ion transmembrane transport|response to drug|drug export|transmembrane transport|,"nucleotide binding|ATP binding|canalicular bile acid transmembrane transporter activity|canalicular bile acid transmembrane transporter activity|drug transmembrane transporter activity|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,-1,7.63,10,0,0,-1,4.8,-4.8,0.278,0,0,-2,-0.1
ENSMUSG00000022849,HSPBAP1,Hspb associated protein 1,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.3,0.765,10,1.7,7.33,1.7,4.77,4.77,0.28,0,0,0.3,3
ENSMUSG00000053024,CNTN2,contactin 2,plasma membrane|voltage-gated potassium channel complex|cell surface|membrane|axon|anchored component of membrane|node of Ranvier|neuron projection|neuronal cell body|myelin sheath|juxtaparanode region of axon|synapse|,microtubule cytoskeleton organization|neuron migration|cell adhesion|cell-matrix adhesion|axonogenesis|axon guidance|axon guidance|axonal fasciculation|learning|adult walking behavior|regulation of cell morphogenesis involved in differentiation|positive regulation of protein processing|cerebral cortex GABAergic interneuron migration|central nervous system myelination|regulation of axon diameter|neuron projection development|receptor internalization|cellular protein localization|clustering of voltage-gated potassium channels|negative regulation of neuron differentiation|regulation of neuronal synaptic plasticity|regulation of astrocyte differentiation|positive regulation of adenosine receptor signaling pathway|protein localization to juxtaparanode region of axon|protein localization to juxtaparanode region of axon|establishment of protein localization to juxtaparanode region of axon|presynaptic membrane organization|,glycoprotein binding|protein binding|carbohydrate binding|protein self-association|,10,1.2,5.54,10,0.4,1.41,0.5,4.75,4.75,0.281,0,0,-0.1,2.7
ENSMUSG00000030965,FAM175B,"family with sequence similarity 175, member B",nucleus|cytoplasm|BRISC complex|,cellular response to freezing|,protein binding|polyubiquitin binding|,10,0.6,1.81,10,0.5,3.3,0.5,4.75,4.75,0.281,0,0,-0.2,1.4
ENSMUSG00000034906,NCAPH,"non-SMC condensin I complex, subunit H",condensin complex|nucleus|chromosome|cytoplasm|microtubule cytoskeleton|membrane|,cell cycle|mitotic nuclear division|mitotic chromosome condensation|chromosome condensation|cell division|,None,9,0.5,3.95,9,-0.8,4.26,0.6,4.7,4.7,0.284,0,0,-1.4,1.5
ENSMUSG00000027863,CD2,CD2 antigen,extracellular region|cell-cell junction|external side of plasma membrane|external side of plasma membrane|cytoplasmic side of plasma membrane|cell surface|membrane|integral component of membrane|protein complex|membrane raft|anchored component of plasma membrane|,cell adhesion|single organismal cell-cell adhesion|positive regulation of tumor necrosis factor production|heterotypic cell-cell adhesion|T cell activation|positive regulation of interferon-gamma secretion|positive regulation of interleukin-8 secretion|,glycoprotein binding|antigen binding|receptor activity|receptor binding|protein binding|protein kinase binding|receptor tyrosine kinase binding|protein homodimerization activity|protein homodimerization activity|protein self-association|,10,1.4,1.53,10,-0.6,4.56,-0.4,4.7,-4.7,0.284,0,0,-1.9,1.6
ENSMUSG00000026374,TSN,translin,nucleus|cytoplasm|cytoplasm|,None,DNA binding|single-stranded DNA binding|RNA binding|mRNA binding|nuclease activity|endonuclease activity|protein binding|hydrolase activity|protein complex binding|phosphoric ester hydrolase activity|sequence-specific DNA binding|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,-0.4,3.76,10,1.1,2.83,-0.4,4.69,-4.69,0.284,0,0,-1.2,1.5
ENSMUSG00000026656,FCGR2B,"Fc receptor, IgG, low affinity IIb",extracellular region|cytoplasm|cytoskeleton|plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,"negative regulation of type I hypersensitivity|negative regulation of immunoglobulin production|negative regulation of inflammatory response to antigenic stimulus|negative regulation of acute inflammatory response to antigenic stimulus|negative regulation of humoral immune response mediated by circulating immunoglobulin|phagocytosis, engulfment|defense response|immune response|cell surface receptor signaling pathway|response to bacterium|immunoglobulin mediated immune response|antigen processing and presentation of exogenous peptide antigen via MHC class II|negative regulation of B cell proliferation|negative regulation of interleukin-10 production|intracellular signal transduction|negative regulation of phagocytosis|positive regulation of phagocytosis|negative regulation of immune response|cellular response to molecule of bacterial origin|",receptor signaling protein activity|protein binding|IgG binding|,10,-0.3,0.653,10,-0.4,4.45,-0.3,4.69,-4.69,0.284,0,0,-1.2,0.2
ENSMUSG00000039055,EME1,essential meiotic endonuclease 1 homolog 1 (S. pombe),nuclear chromatin|nucleus|nuclear heterochromatin|cytoplasm|,DNA repair|DNA recombination|cellular response to DNA damage stimulus|response to intra-S DNA damage checkpoint signaling|,DNA binding|nuclease activity|endonuclease activity|protein binding|hydrolase activity|metal ion binding|,10,0,0,10,-1.7,8,-1.6,4.69,-4.69,0.284,0,0,-3,1.1
ENSMUSG00000020994,PNN,pinin,nucleus|spliceosomal complex|cytoplasm|membrane|nuclear speck|cell junction|desmosome|exon-exon junction complex|catalytic step 2 spliceosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|single organismal cell-cell adhesion|",DNA binding|poly(A) RNA binding|,10,-0.4,2.98,10,1.3,2.4,-0.5,4.69,-4.69,0.284,0,0,-1.6,1.4
ENSMUSG00000024420,ZFP521,zinc finger protein 521,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell differentiation|",nucleic acid binding|DNA binding|protein domain specific binding|metal ion binding|,10,-1.1,5.39,10,0.4,1.11,-1,4.64,-4.64,0.287,0,0,-2,0.6
ENSMUSG00000068101,CENPM,centromere protein M,"chromosome, centromeric region|kinetochore|cellular_component|nucleus|chromosome|cytoplasm|",biological_process|,molecular_function|,9,-1.1,6.58,9,0.5,1.38,-1,4.63,-4.63,0.288,0,0,-2,0.6
ENSMUSG00000017221,PSMD3,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 3",proteasome complex|nucleus|cytoplasm|proteasome regulatory particle|membrane|proteasome accessory complex|extracellular vesicular exosome|,regulation of protein catabolic process|,protein binding|enzyme regulator activity|,10,0.4,0.588,8,0.9,5.11,0.5,4.6,4.6,0.29,0,0,-0.2,1.9
ENSMUSG00000035048,ANAPC13,anaphase promoting complex subunit 13,nucleus|anaphase-promoting complex|,cell cycle|mitotic nuclear division|cell division|protein K11-linked ubiquitination|,molecular_function|,9,0.5,2.59,10,0.6,2.37,0.6,4.59,4.59,0.29,0,0,-0.6,1.6
ENSMUSG00000003923,TFAM,"transcription factor A, mitochondrial",nucleus|transcription factor complex|mitochondrion|mitochondrion|mitochondrial nucleoid|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from mitochondrial promoter|transcription initiation from mitochondrial promoter|mitochondrial respiratory chain complex assembly|positive regulation of transcription, DNA-templated|","DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|DNA binding, bending|heat shock protein binding|poly(A) RNA binding|mitochondrial light strand promoter sense binding|",9,-0.8,3.31,7,-0.5,1.7,-0.6,4.57,-4.57,0.291,0,0,-1.8,1
ENSMUSG00000017485,TOP2B,topoisomerase (DNA) II beta,heterochromatin|nucleus|nucleus|nucleoplasm|cytoplasm|cytosol|DNA topoisomerase complex (ATP-hydrolyzing)|,resolution of meiotic recombination intermediates|sister chromatid segregation|neuron migration|ATP catabolic process|ATP catabolic process|DNA metabolic process|DNA topological change|DNA topological change|DNA unwinding involved in DNA replication|mitotic recombination|axonogenesis|forebrain development|mitotic DNA integrity checkpoint|,"nucleotide binding|DNA binding|chromatin binding|DNA topoisomerase activity|DNA topoisomerase type II (ATP-hydrolyzing) activity|DNA topoisomerase type II (ATP-hydrolyzing) activity|protein kinase C binding|protein binding|ATP binding|protein C-terminus binding|DNA binding, bending|isomerase activity|enzyme binding|histone deacetylase binding|metal ion binding|protein heterodimerization activity|",10,-0.4,2.81,9,-0.3,2.13,-0.3,4.57,-4.57,0.291,0,0,-1,1.7
ENSMUSG00000042870,TOM1,target of myb1 homolog (chicken),intracellular|cytoplasm|endosome|early endosome|cytosol|membrane|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|,protein binding|clathrin binding|,10,-0.8,3.76,10,-0.6,1.18,-0.6,4.57,-4.57,0.291,0,0,-1.8,0.4
ENSMUSG00000068798,RAP1A,RAS-related protein-1a,cytoplasm|cytoplasm|endosome|early endosome|late endosome|plasma membrane|membrane|cell junction|guanyl-nucleotide exchange factor complex|neuron projection|perinuclear region of cytoplasm|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|nervous system development|positive regulation of neuron projection development|positive regulation of neuron projection development|protein transport|Rap protein signal transduction|positive regulation of Rap GTPase activity|nerve growth factor signaling pathway|positive regulation of protein kinase activity|establishment of endothelial barrier|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cellular response to cAMP|regulation of cell junction assembly|cellular response to nerve growth factor stimulus|negative regulation of synaptic vesicle exocytosis|positive regulation of vasculogenesis|,nucleotide binding|GTPase activity|protein binding|GTP binding|protein transporter activity|Ras GTPase binding|Rap guanyl-nucleotide exchange factor activity|protein complex binding|,10,0.6,2.82,10,0.9,2.56,0.7,4.57,4.57,0.291,0,0,-0.2,1.8
ENSMUSG00000023175,BSG,basigin,acrosomal membrane|mitochondrion|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|sarcolemma|membrane raft|extracellular vesicular exosome|,protein targeting to plasma membrane|,mannose binding|,10,-0.6,5.34,10,-0.1,0.237,-0.5,4.56,-4.56,0.292,0,0,-1.5,0.1
ENSMUSG00000061524,ZIC2,zinc finger protein of the cerebellum 2,nucleus|cytoplasm|,"neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|central nervous system development|visual perception|cell differentiation|retinal ganglion cell axon guidance|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|developmental pigmentation|positive regulation of sequence-specific DNA binding transcription factor activity|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|chromatin DNA binding|metal ion binding|,10,0.8,2.42,10,0.4,3.26,0.4,4.5,4.5,0.295,0,0,-0.1,1.5
ENSMUSG00000049300,PRMT6,protein arginine N-methyltransferase 6,nucleus|cytosol|,"DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein methylation|cellular response to DNA damage stimulus|chromatin modification|histone methylation|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|methylation|histone arginine methylation|histone H3-R2 methylation|histone H4-R3 methylation|negative regulation of transcription, DNA-templated|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N monomethyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|histone methyltransferase activity|histone binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|histone methyltransferase activity (H4-R3 specific)|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|histone methyltransferase activity (H3-R2 specific)|histone methyltransferase activity (H2A-R3 specific)|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.3,1.55,10,0.6,3.25,0.6,4.48,4.48,0.296,0,0,-0.1,1.5
ENSMUSG00000031241,TBX22,T-box 22,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,2,4.04,10,0.8,3.92,1.6,4.45,4.45,0.298,0,0,-0.1,3
ENSMUSG00000022678,NDE1,nuclear distribution gene E homolog 1 (A nidulans),"chromosome, centromeric region|kinetochore|intracellular|cell|chromosome|cytoplasm|centrosome|centrosome|microtubule organizing center|spindle|cytoskeleton|microtubule|membrane|spindle pole centrosome|",establishment of mitotic spindle orientation|neuron migration|microtubule nucleation|cell cycle|mitotic nuclear division|multicellular organismal development|nervous system development|neuroblast proliferation|cerebral cortex development|cerebral cortex development|cell differentiation|forebrain development|microtubule organizing center organization|vesicle transport along microtubule|centrosome duplication|cell division|establishment of chromosome localization|,protein binding|microtubule binding|protein domain specific binding|identical protein binding|,10,0.4,2.73,10,0.4,1.97,0.4,4.44,4.44,0.299,0,0,-0.2,1.5
ENSMUSG00000005583,MEF2C,myocyte enhancer factor 2C,intracellular|nucleus|nucleus|nucleus|cytoplasm|cytosol|nuclear speck|sarcomere|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|MAPK cascade|MAPK cascade|blood vessel development|osteoblast differentiation|B cell homeostasis|heart looping|endochondral ossification|endochondral ossification|blood vessel remodeling|chondrocyte differentiation|germinal center formation|regulation of germinal center formation|response to ischemia|primary heart field specification|secondary heart field specification|outflow tract morphogenesis|sinoatrial valve morphogenesis|cardiac ventricle formation|cardiac ventricle formation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|apoptotic process|humoral immune response|multicellular organismal development|nervous system development|heart development|skeletal muscle tissue development|muscle cell fate determination|learning or memory|positive regulation of cardiac muscle hypertrophy|positive regulation of gene expression|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|positive regulation of alkaline phosphatase activity|neural crest cell differentiation|cardiac muscle hypertrophy in response to stress|cell differentiation|neuron differentiation|platelet formation|monocyte differentiation|negative regulation of ossification|melanocyte differentiation|positive regulation of bone mineralization|positive regulation of B cell proliferation|cellular response to drug|skeletal muscle cell differentiation|skeletal muscle cell differentiation|cellular response to trichostatin A|B cell proliferation|positive regulation of MAP kinase activity|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|cell fate commitment|regulation of megakaryocyte differentiation|positive regulation of myoblast differentiation|positive regulation of neuron differentiation|positive regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of skeletal muscle tissue development|neuron development|embryonic viscerocranium morphogenesis|embryonic skeletal system morphogenesis|negative regulation of epithelial cell proliferation|B cell receptor signaling pathway|smooth muscle cell differentiation|cardiac muscle cell differentiation|cardiac muscle cell differentiation|ventricular cardiac muscle cell differentiation|palate development|regulation of synaptic activity|positive regulation of cardiac muscle cell proliferation|transdifferentiation|regulation of sarcomere organization|cartilage morphogenesis|renal tubule morphogenesis|cellular response to lipopolysaccharide|cellular response to calcium ion|cellular response to retinoic acid|cellular response to growth factor stimulus|cellular response to parathyroid hormone stimulus|cellular response to fluid shear stress|cellular response to transforming growth factor beta stimulus|positive regulation of cell proliferation in bone marrow|glomerulus morphogenesis|nephron tubule epithelial cell differentiation|positive regulation of protein homodimerization activity|positive regulation of macrophage apoptotic process|positive regulation of cardiac muscle cell differentiation|positive regulation of cardiac muscle cell differentiation|positive regulation of behavioral fear response|epithelial cell proliferation involved in renal tubule morphogenesis|positive regulation of skeletal muscle cell differentiation|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|core promoter proximal region sequence-specific DNA binding|core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|AT DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|activating transcription factor binding|miRNA binding|histone deacetylase binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|HMG box domain binding|,10,-0.9,6.61,10,-0.1,0.241,-0.7,4.44,-4.44,0.299,0,0,-1.9,0
ENSMUSG00000008601,RAB25,"RAB25, member RAS oncogene family",plasma membrane|membrane|pseudopodium|cytoplasmic vesicle|cell projection|extracellular vesicular exosome|,transport|small GTPase mediated signal transduction|positive regulation of cell proliferation|protein transport|pseudopodium organization|,nucleotide binding|protein binding|GTP binding|,10,-0.2,0.428,10,-0.5,5.31,-0.4,4.43,-4.43,0.299,0,0,-1.4,0.4
ENSMUSG00000049653,SPATC1,spermatogenesis and centriole associated 1,cytoplasm|centrosome|centrosome|cytoskeleton|,biological_process|,protein binding|gamma-tubulin binding|,10,0.5,1.08,10,1.6,6.01,1.5,4.43,4.43,0.299,0,0,0.1,3
ENSMUSG00000038845,PHB,prohibitin,nucleus|nucleus|nucleoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|integral component of plasma membrane|membrane|mitochondrial crista|extrinsic component of mitochondrial outer membrane|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|osteoblast differentiation|DNA replication|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of cell proliferation|negative regulation of transcription by competitive promoter binding|histone deacetylation|negative regulation of cell growth|negative regulation of apoptotic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|progesterone receptor signaling pathway|negative regulation of androgen receptor signaling pathway|cellular response to interleukin-6|DNA biosynthetic process|negative regulation of glucocorticoid receptor signaling pathway|",sequence-specific DNA binding RNA polymerase II transcription factor activity|enzyme binding|histone deacetylase binding|transcription regulatory region DNA binding|,8,-1.6,4,8,1.9,3.9,0.5,4.42,4.42,0.3,0,0,-2,3
ENSMUSG00000057236,RBBP4,retinoblastoma binding protein 4,nuclear chromatin|nucleus|nucleus|nucleoplasm|NuRD complex|NuRD complex|NURF complex|CAF-1 complex|ESC/E(Z) complex|ESC/E(Z) complex|protein complex|,"ATP catabolic process|DNA replication|DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|chromatin remodeling|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|chromatin modification|chromatin assembly|ATP-dependent chromatin remodeling|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|protein binding|DNA-dependent ATPase activity|nucleosomal DNA binding|histone deacetylase binding|,6,-0.9,4.45,6,-0.4,0.823,-0.7,4.42,-4.42,0.3,0,0,-2,0.2
ENSMUSG00000030170,WNT5B,"wingless-type MMTV integration site family, member 5B",extracellular region|proteinaceous extracellular matrix|extracellular space|cell surface|extracellular matrix|extracellular vesicular exosome|,signal transduction|cell-cell signaling|multicellular organismal development|organ morphogenesis|Wnt signaling pathway|neuron differentiation|positive regulation of cell migration|cell fate commitment|positive regulation of fat cell differentiation|negative regulation of canonical Wnt signaling pathway|,receptor binding|receptor binding|frizzled binding|protein binding|,10,0.5,1.61,10,0.6,3.08,0.6,4.41,4.41,0.3,0,0,-0.3,1.6
ENSMUSG00000058835,ABI1,abl-interactor 1,intracellular|nucleus|cytoplasm|cytoskeleton|plasma membrane|membrane|lamellipodium|lamellipodium|lamellipodium|cell junction|filopodium|SCAR complex|cell leading edge|cell projection|neuron projection|synapse|postsynaptic membrane|extracellular vesicular exosome|,somitogenesis|cellular component movement|cellular process|cellular process|peptidyl-tyrosine phosphorylation|megakaryocyte development|positive regulation of protein tyrosine kinase activity|lamellipodium morphogenesis|,protein binding|protein tyrosine kinase activator activity|protein complex binding|,9,-0.7,4.76,9,1.2,4.65,-0.8,4.4,-4.4,0.301,0,0,-2,1.5
ENSMUSG00000025950,IDH1,"isocitrate dehydrogenase 1 (NADP+), soluble",cytoplasm|mitochondrion|peroxisome|cytosol|cytosol|extracellular vesicular exosome|,glyoxylate cycle|tricarboxylic acid cycle|isocitrate metabolic process|2-oxoglutarate metabolic process|glutathione metabolic process|response to oxidative stress|response to organic cyclic compound|response to steroid hormone|oxidation-reduction process|,"magnesium ion binding|isocitrate dehydrogenase (NADP+) activity|isocitrate dehydrogenase (NADP+) activity|receptor binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|protein homodimerization activity|metal ion binding|NADP binding|NAD binding|",10,0.7,3.75,10,0.4,1.48,0.5,4.38,4.38,0.302,0,0,-0.1,1.5
ENSMUSG00000022023,WBP4,WW domain binding protein 4,nucleus|spliceosomal complex|plasma membrane|nuclear speck|,"mRNA processing|RNA splicing|mRNA cis splicing, via spliceosome|",nucleic acid binding|protein binding|zinc ion binding|metal ion binding|proline-rich region binding|,10,1,7.14,9,-0.4,2.55,1,4.34,4.34,0.304,0,0,-0.8,2
ENSMUSG00000020185,E2F7,E2F transcription factor 7,intracellular|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|placenta development|sprouting angiogenesis|sprouting angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|cell cycle|negative regulation of cell proliferation|negative regulation of cell proliferation|DNA damage response, signal transduction by p53 class mediator|negative regulation of cytokinesis|positive regulation of DNA endoreduplication|positive regulation of transcription from RNA polymerase II promoter|trophoblast giant cell differentiation|chorionic trophoblast cell differentiation|hepatocyte differentiation|negative regulation of transcription involved in G1/S transition of mitotic cell cycle|negative regulation of G1/S transition of mitotic cell cycle|",RNA polymerase II regulatory region sequence-specific DNA binding|core promoter binding|core promoter binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|transcription corepressor activity|protein binding|identical protein binding|,10,-0.9,6.83,10,1.9,2.17,-0.6,4.33,-4.33,0.305,0,0,-2,1.8
ENSMUSG00000019923,ZWINT,ZW10 interactor,"chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|dendrite|neuron projection|intracellular membrane-bounded organelle|",mitotic sister chromatid segregation|cell cycle|mitotic nuclear division|mitotic cell cycle checkpoint|cell division|establishment of localization in cell|,protein N-terminus binding|,9,-0.8,0.546,8,-1.6,5.33,-1.5,4.32,-4.32,0.306,0,0,-3,0.4
ENSMUSG00000000776,POLR3D,polymerase (RNA) III (DNA directed) polypeptide D,nuclear chromatin|nuclear chromatin|nucleus|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|,"immune system process|transcription, DNA-templated|transcription from RNA polymerase III promoter|positive regulation of interferon-beta production|innate immune response|positive regulation of innate immune response|defense response to virus|",RNA polymerase III activity|DNA binding|chromatin binding|DNA-directed RNA polymerase activity|,10,-0.5,2.69,10,0.8,2.59,-0.4,4.26,-4.26,0.31,0,0,-1.3,1.4
ENSMUSG00000003032,KLF4,Kruppel-like factor 4 (gut),chromatin|nuclear chromatin|nucleus|nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of cell proliferation|epidermal cell differentiation|response to organic substance|negative regulation of phosphatidylinositol 3-kinase signaling|negative regulation of muscle hyperplasia|stem cell maintenance|cell differentiation|post-embryonic camera-type eye development|negative regulation of NF-kappaB transcription factor activity|positive regulation of cellular protein metabolic process|response to retinoic acid|negative regulation of heterotypic cell-cell adhesion|post-embryonic hemopoiesis|regulation of cell proliferation|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of phosphatidylinositol 3-kinase activity|negative regulation of interleukin-8 biosynthetic process|positive regulation of nitric oxide biosynthetic process|fat cell differentiation|regulation of cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hemoglobin biosynthetic process|negative regulation of smooth muscle cell proliferation|epidermis morphogenesis|positive regulation of protein metabolic process|negative regulation of protein kinase B signaling|negative regulation of response to cytokine stimulus|negative regulation of ERK1 and ERK2 cascade|cellular response to growth factor stimulus|cellular response to laminar fluid shear stress|negative regulation of cell migration involved in sprouting angiogenesis|negative regulation of chemokine (C-X-C motif) ligand 2 production|",core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding transcription factor recruiting transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|transcription cofactor binding|nucleic acid binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription factor binding|phosphatidylinositol 3-kinase regulator activity|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0.9,5.34,10,0,0,0.8,4.26,4.26,0.31,0,0,0,1.8
ENSMUSG00000031549,IDO2,"indoleamine 2,3-dioxygenase 2",cytoplasm|,tryptophan catabolic process to kynurenine|tryptophan catabolic process to kynurenine|tryptophan catabolic process to kynurenine|oxidation-reduction process|,"tryptophan 2,3-dioxygenase activity|oxidoreductase activity|2,3-dihydroxy DDT 1,2-dioxygenase activity|phenanthrene dioxygenase activity|2,2',3-trihydroxybiphenyl dioxygenase activity|1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity|5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity|1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity|protocatechuate 3,4-dioxygenase type II activity|2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity|3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity|2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity|carbazole 1,9a-dioxygenase activity|dihydroxydibenzothiophene dioxygenase activity|1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity|styrene dioxygenase activity|3,4-dihydroxyphenanthrene dioxygenase activity|hydroquinone 1,2-dioxygenase activity|p-cumate 2,3-dioxygenase activity|2,3-dihydroxy-p-cumate dioxygenase activity|3,5-dichlorocatechol 1,2-dioxygenase activity|2-aminophenol 1,6-dioxygenase activity|2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity|chlorocatechol 1,2-dioxygenase activity|catechol dioxygenase activity|dihydroxyfluorene dioxygenase activity|heme binding|indoleamine 2,3-dioxygenase activity|indoleamine 2,3-dioxygenase activity|indoleamine 2,3-dioxygenase activity|5-aminosalicylate dioxygenase activity|3-hydroxy-2-naphthoate 2,3-dioxygenase activity|benzo(a)pyrene 11,12-dioxygenase activity|benzo(a)pyrene 4,5-dioxygenase activity|4,5-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 9,10-dioxygenase activity|9,10-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 7,8-dioxygenase activity|7,8-dihydroxy benzo(a)pyrene dioxygenase activity|1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity|2-mercaptobenzothiazole dioxygenase activity|pyridine-3,4-diol dioxygenase activity|pyrene dioxygenase activity|4,5-dihydroxypyrene dioxygenase activity|phenanthrene-4-carboxylate dioxygenase activity|tetrachlorobenzene dioxygenase activity|4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity|2,3-dihydroxydiphenyl ether dioxygenase activity|diphenyl ether 1,2-dioxygenase activity|arachidonate 8(S)-lipoxygenase activity|metal ion binding|4-hydroxycatechol 1,2-dioxygenase activity|dioxygenase activity|",10,0.8,5.57,10,-0.1,0.0806,0.8,4.24,4.24,0.311,0,0,-0.1,1.8
ENSMUSG00000059495,ARHGEF12,Rho guanine nucleotide exchange factor (GEF) 12,cytoplasm|membrane|extracellular vesicular exosome|,G-protein coupled receptor signaling pathway|regulation of Rho protein signal transduction|intracellular signal transduction|termination of G-protein coupled receptor signaling pathway|,G-protein coupled receptor binding|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|,10,-0.9,6.18,10,-0.1,0.125,-0.9,4.23,-4.23,0.312,0,0,-2,0.4
ENSMUSG00000017390,ALDOC,"aldolase C, fructose-bisphosphate",cytoplasm|mitochondrion|axon|extracellular vesicular exosome|,"glycolytic process|apoptotic process|aging|fructose 1,6-bisphosphate metabolic process|protein homotetramerization|protein heterotetramerization|",catalytic activity|fructose-bisphosphate aldolase activity|fructose-bisphosphate aldolase activity|cytoskeletal protein binding|lyase activity|,10,-1,4.16,10,-0.3,1.88,-0.6,4.21,-4.21,0.313,0,0,-1.8,0.1
ENSMUSG00000027284,CDAN1,"congenital dyserythropoietic anemia, type I (human)",nucleus|nucleus|cytoplasm|plasma membrane|endomembrane system|endomembrane system|,chromatin organization|nuclear envelope organization|protein localization|negative regulation of DNA replication|chromatin assembly|,molecular_function|,8,-1.6,3.69,8,0.5,4.97,-1.5,4.19,-4.19,0.314,0,0,-3,1.1
ENSMUSG00000078812,EIF5A,eukaryotic translation initiation factor 5A,nucleus|nucleus|annulate lamellae|nuclear pore|cytoplasm|cytoplasm|endoplasmic reticulum|membrane|membrane|dendrite|neuronal cell body|extracellular vesicular exosome|,mRNA export from nucleus|translation|translational elongation|translational frameshifting|protein export from nucleus|transport|apoptotic process|positive regulation of cell proliferation|peptidyl-lysine modification to peptidyl-hypusine|protein transport|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of translational elongation|positive regulation of translational termination|mRNA transport|positive regulation of muscle cell differentiation|,RNA binding|translation elongation factor activity|U6 snRNA binding|ribosome binding|poly(A) RNA binding|protein N-terminus binding|,5,0.8,5.5,6,0,0,0.8,4.18,4.18,0.315,0,0,-1.1,2
ENSMUSG00000014668,CHFR,checkpoint with forkhead and ring finger domains,nucleus|PML body|,protein polyubiquitination|protein polyubiquitination|mitotic cell cycle|ubiquitin-dependent protein catabolic process|cell cycle|mitotic nuclear division|mitotic cell cycle checkpoint|protein ubiquitination|modification-dependent protein catabolic process|cell division|,"nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.5,3.92,9,0.2,0.903,0.4,4.18,4.18,0.315,0,0,-0.6,1.7
ENSMUSG00000079440,ALPI,"alkaline phosphatase, intestinal",external side of plasma membrane|cell surface|,phosphorus metabolic process|dephosphorylation|,magnesium ion binding|alkaline phosphatase activity|zinc ion binding|hydrolase activity|protein homodimerization activity|,10,0,0,10,1.7,7.38,1.7,4.17,4.17,0.315,0,0,0.3,3
ENSMUSG00000024960,PLCB3,"phospholipase C, beta 3",nucleus|cytosol|sarcolemma|protein complex|,regulation of systemic arterial blood pressure|lipid metabolic process|post-Golgi vesicle-mediated transport|signal transduction|G-protein coupled receptor signaling pathway|synaptic transmission|phospholipid catabolic process|lipid catabolic process|intracellular signal transduction|,phosphatidylinositol phospholipase C activity|phospholipase C activity|signal transducer activity|calcium ion binding|calmodulin binding|phosphoric diester hydrolase activity|hydrolase activity|,10,0.2,0.266,10,1.2,4.39,0.5,4.16,4.16,0.316,0,0,0.1,1.9
ENSMUSG00000057113,NPM1,nucleophosmin 1,granular component|intracellular|cell|nucleus|nucleus|nucleoplasm|nucleoplasm|nucleolus|nucleolus|cytoplasm|cytoplasm|centrosome|centrosome|cytosol|cytoskeleton|large ribosomal subunit|small ribosomal subunit|membrane|nuclear speck|ribonucleoprotein complex|spindle pole centrosome|,"ribosomal large subunit export from nucleus|ribosomal small subunit export from nucleus|DNA repair|nucleosome assembly|rRNA export from nucleus|rRNA export from nucleus|cell volume homeostasis|cell volume homeostasis|nucleocytoplasmic transport|nucleocytoplasmic transport|response to stress|centrosome cycle|cell aging|protein localization|protein localization|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|regulation of centrosome duplication|positive regulation of centrosome duplication|negative regulation of centrosome duplication|cell growth|positive regulation of cellular biosynthetic process|positive regulation of cellular biosynthetic process|protein destabilization|regulation of endodeoxyribonuclease activity|ribosomal large subunit biogenesis|ribosomal large subunit biogenesis|ribosomal small subunit biogenesis|ribosomal small subunit biogenesis|negative regulation of apoptotic process|positive regulation of catalytic activity|regulation of DNA damage response, signal transduction by p53 class mediator|regulation of neuron apoptotic process|negative regulation of protein kinase activity by regulation of protein phosphorylation|positive regulation of translation|positive regulation of DNA replication|positive regulation of protein kinase activity|regulation of centriole replication|negative regulation of mRNA splicing, via spliceosome|positive regulation of DNA metabolic process|positive regulation of NF-kappaB transcription factor activity|protein oligomerization|protein homooligomerization|regulation of cell cycle|regulation of endoribonuclease activity|regulation of eIF2 alpha phosphorylation by dsRNA|","nucleic acid binding|DNA binding|transcription coactivator activity|RNA binding|RNA binding|protein kinase inhibitor activity|protein binding|phosphatidylinositol-3,4,5-trisphosphate binding|rRNA binding|enzyme binding|protein kinase binding|Tat protein binding|histone binding|protein homodimerization activity|ribosomal large subunit binding|ribosomal small subunit binding|poly(A) RNA binding|protein heterodimerization activity|NF-kappaB binding|unfolded protein binding|",8,-0.4,0.808,8,-1,4.65,-0.8,4.14,-4.14,0.317,0,0,-2,0.3
ENSMUSG00000006335,TFPT,TCF3 (E2A) fusion partner,nucleus|nucleolus|cytoplasm|actin filament|Ino80 complex|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cellular response to DNA damage stimulus|positive regulation of apoptotic process|apoptotic signaling pathway|",DNA binding|protein kinase binding|protein heterodimerization activity|,10,-0.4,2.31,10,-0.3,2.09,-0.3,4.12,-4.12,0.319,0,0,-1.4,0.4
ENSMUSG00000028496,MLLT3,"myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3",nucleus|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|segment specification|anterior/posterior pattern specification|negative regulation of canonical Wnt signaling pathway|positive regulation of Wnt signaling pathway, planar cell polarity pathway|",protein binding|,10,-0.4,2.64,10,-1.2,2.69,-0.4,4.11,-4.11,0.319,0,0,-2,0.7
ENSMUSG00000047897,RIPPLY2,ripply2 homolog (zebrafish),nucleus|,ossification|somitogenesis|somitogenesis|Notch signaling pathway|multicellular organismal development|determination of left/right symmetry|axis specification|regulation of gene expression|somite rostral/caudal axis specification|somite rostral/caudal axis specification|post-anal tail morphogenesis|bone morphogenesis|,None,10,0.2,1.06,10,1.1,4.68,0.5,4.11,4.11,0.319,0,0,0,1.9
ENSMUSG00000013787,EHMT2,euchromatic histone lysine N-methyltransferase 2,nucleus|chromosome|,negative regulation of transcription from RNA polymerase II promoter|regulation of DNA replication|regulation of DNA replication|DNA methylation|regulation of transcription from RNA polymerase II promoter|synaptonemal complex assembly|germ cell development|spermatid development|fertilization|DNA methylation on cytosine within a CG sequence|chromatin modification|histone methylation|histone methylation|peptidyl-lysine methylation|peptidyl-lysine dimethylation|methylation|histone lysine methylation|organ growth|histone H3-K9 methylation|histone H3-K9 methylation|histone H3-K27 methylation|histone H3-K27 methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|p53 binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|zinc ion binding|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone-lysine N-methyltransferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|histone methyltransferase activity (H3-K9 specific)|histone methyltransferase activity (H3-K9 specific)|histone methyltransferase activity (H3-K27 specific)|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|C2H2 zinc finger domain binding|C2H2 zinc finger domain binding|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.9,1.24,10,0.6,3.56,0.5,4.1,4.1,0.32,0,0,0,1.7
ENSMUSG00000031028,TUB,tubby candidate gene,extracellular region|nucleus|cytoplasm|cytosol|plasma membrane|membrane|,phagocytosis|G-protein coupled receptor signaling pathway|phototransduction|sensory perception of sound|detection of visible light|multicellular organismal macromolecule metabolic process|positive regulation of phagocytosis|response to stimulus|retina development in camera-type eye|receptor localization to nonmotile primary cilium|,protein binding|G-protein coupled photoreceptor activity|protein complex binding|,10,0,0,10,1.6,7.35,1.6,4.06,4.06,0.322,0,0,0.2,3
ENSMUSG00000020380,RAD50,RAD50 homolog (S. cerevisiae),"chromosome, telomeric region|nuclear chromosome, telomeric region|nuclear chromatin|condensed nuclear chromosome|nucleus|nucleus|nucleoplasm|chromosome|membrane|inclusion body|Mre11 complex|site of double-strand break|pronucleus|perinuclear region of cytoplasm|","regulation of mitotic recombination|DNA catabolic process, endonucleolytic|DNA repair|double-strand break repair|DNA recombination|cellular response to DNA damage stimulus|telomere maintenance via telomerase|cell cycle|meiotic nuclear division|positive regulation of protein autophosphorylation|DNA duplex unwinding|positive regulation of kinase activity|protein heterooligomerization|nucleic acid phosphodiester bond hydrolysis|","single-stranded DNA endodeoxyribonuclease activity|nucleotide binding|DNA binding|ATP-dependent DNA helicase activity|nuclease activity|ATP binding|zinc ion binding|3'-5' exonuclease activity|hydrolase activity|protein binding, bridging|metal ion binding|",9,1.4,4.92,10,0.1,0.0706,-0.5,4.06,-4.06,0.322,0,0,-1.3,2.7
ENSMUSG00000015854,CD5L,CD5 antigen-like,extracellular region|membrane|extracellular vesicular exosome|blood microparticle|,apoptotic process|,scavenger receptor activity|,10,0,0,10,0.6,6.22,0.5,4.04,4.04,0.324,0,0,0,1.9
ENSMUSG00000031448,ADPRHL1,ADP-ribosylhydrolase like 1,cellular_component|,biological_process|protein de-ADP-ribosylation|,magnesium ion binding|molecular_function|ADP-ribosylarginine hydrolase activity|hydrolase activity|,10,-0.2,0.973,10,-0.6,4.43,-0.4,4.04,-4.04,0.324,0,0,-1.7,0.7
ENSMUSG00000054626,XLR,X-linked lymphocyte-regulated,cellular_component|,biological_process|,molecular_function|,9,-0.4,3,9,-0.5,1.27,-0.4,4.02,-4.02,0.325,0,0,-1.6,0.2
ENSMUSG00000058019,CES5A,carboxylesterase 5A,cellular_component|extracellular region|,biological_process|,hydrolase activity|carboxylic ester hydrolase activity|,10,0.7,6.12,10,-0.2,0.153,0.6,4.02,4.02,0.325,0,0,-0.4,1.7
ENSMUSG00000061864,GALNTL6,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-0.6,4.09,10,-0.2,0.721,-0.5,4.02,-4.02,0.325,0,0,-1.7,0.3
ENSMUSG00000029405,G3BP2,GTPase activating protein (SH3 domain) binding protein 2,intracellular|cytoplasm|,transport|small GTPase mediated signal transduction|mRNA transport|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.5,2.19,10,0.7,2.38,0.6,4.02,4.02,0.325,0,0,-0.1,1.5
ENSMUSG00000063568,JAZF1,JAZF zinc finger 1,nucleus|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|transcription corepressor activity|metal ion binding|,10,2.1,7.47,10,0,0,2.1,4.01,4.01,0.326,0,0,0.2,4
ENSMUSG00000027239,MDK,midkine,extracellular region|cytoplasm|cell projection|,"behavioral fear response|multicellular organismal development|short-term memory|response to wounding|response to wounding|cell migration|cerebellar granular layer development|hippocampus development|cell differentiation|adrenal gland development|defecation|negative regulation of neuron apoptotic process|positive regulation of transcription, DNA-templated|regulation of behavior|positive regulation of cell division|negative regulation of neuron death|",growth factor activity|heparin binding|,10,-0.9,2.59,10,-0.3,2.56,-0.4,4,-4,0.327,0,0,-1.7,0.2
ENSMUSG00000028703,LRRC41,leucine rich repeat containing 41,nucleus|cytoplasm|membrane|,biological_process|,protein binding|protein homodimerization activity|,10,0,0,10,1.8,6.74,1.7,4,4,0.327,0,0,-0.1,3
ENSMUSG00000029828,4921507P07RIK,RIKEN cDNA 4921507P07 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,1.31,10,0.6,2.99,0.5,3.97,3.97,0.328,0,0,-0.3,1.5
ENSMUSG00000037992,RARA,"retinoic acid receptor, alpha",nuclear chromatin|nucleus|nucleus|cytoplasm|cytoplasm|dendrite|dendrite|neuron projection|neuronal cell body|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|ureteric bud development|neural tube closure|glandular epithelial cell development|outflow tract septum morphogenesis|growth plate cartilage development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|signal transduction|germ cell development|spermatogenesis|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|male gonad development|positive regulation of gene expression|negative regulation of gene expression|positive regulation of phosphatidylinositol 3-kinase signaling|negative regulation of translation|intracellular estrogen receptor signaling pathway|regulation of granulocyte differentiation|negative regulation of granulocyte differentiation|embryonic camera-type eye development|regulation of myelination|response to estradiol|response to retinoic acid|response to retinoic acid|negative regulation of interferon-gamma production|negative regulation of tumor necrosis factor production|positive regulation of interleukin-13 production|positive regulation of interleukin-4 production|positive regulation of interleukin-5 production|multicellular organism growth|regulation of apoptotic process|negative regulation of apoptotic process|apoptotic cell clearance|steroid hormone mediated signaling pathway|regulation of phosphatidylinositol 3-kinase activity|response to ethanol|negative regulation of cell differentiation|positive regulation of T-helper 2 cell differentiation|positive regulation of neuron differentiation|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of translational initiation|regulation of synaptic plasticity|retinoic acid receptor signaling pathway|retinoic acid receptor signaling pathway|positive regulation of binding|positive regulation of protein kinase B signaling|ventricular cardiac muscle cell differentiation|Sertoli cell fate commitment|limb development|face development|bone development|trachea cartilage development|chondroblast differentiation|negative regulation of cartilage development|positive regulation of ERK1 and ERK2 cascade|cellular response to lipopolysaccharide|cellular response to retinoic acid|cellular response to estrogen stimulus|","translation repressor activity, nucleic acid binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region DNA binding|retinoic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|retinoic acid receptor activity|retinoic acid receptor activity|transcription coactivator activity|transcription corepressor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|receptor binding|protein binding|transcription factor binding|transcription factor binding|drug binding|zinc ion binding|enzyme binding|protein domain specific binding|chromatin DNA binding|phosphatidylinositol 3-kinase regulator activity|protein kinase B binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|retinoic acid-responsive element binding|metal ion binding|protein heterodimerization activity|mRNA 5'-UTR binding|protein kinase A binding|",9,0.3,0.525,9,1.2,4.37,0.4,3.96,3.96,0.329,0,0,-0.1,2
ENSMUSG00000025810,NRP1,neuropilin 1,extracellular space|early endosome|cytosol|neurofilament|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|axon|axon|growth cone|neuronal cell body|sorting endosome|,angiogenesis|angiogenesis|angiogenesis|patterning of blood vessels|neuron migration|sprouting angiogenesis|cell migration involved in sprouting angiogenesis|cell migration involved in sprouting angiogenesis|cell adhesion|multicellular organismal development|nervous system development|axon guidance|axon guidance|axon guidance|axonal fasciculation|heart development|organ morphogenesis|dendrite development|cell migration|peptidyl-tyrosine phosphorylation|trigeminal nerve morphogenesis|nerve development|gonadotrophin-releasing hormone neuronal migration to the hypothalamus|cell differentiation|negative regulation of axon extension|retinal ganglion cell axon guidance|cellular response to hepatocyte growth factor stimulus|endothelial cell chemotaxis|cellular response to vascular endothelial growth factor stimulus|vascular endothelial growth factor signaling pathway|VEGF-activated neuropilin signaling pathway|negative regulation of neuron apoptotic process|platelet-derived growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|hepatocyte growth factor receptor signaling pathway|sympathetic nervous system development|neuron development|regulation of axon extension involved in axon guidance|positive regulation of axon extension involved in axon guidance|negative regulation of axon extension involved in axon guidance|negative regulation of axon extension involved in axon guidance|artery morphogenesis|axon extension involved in axon guidance|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|axonogenesis involved in innervation|dichotomous subdivision of terminal units involved in salivary gland branching|dichotomous subdivision of terminal units involved in salivary gland branching|angiogenesis involved in coronary vascular morphogenesis|cell migration involved in coronary vasculogenesis|coronary artery morphogenesis|retina vasculature morphogenesis in camera-type eye|renal artery morphogenesis|sympathetic ganglion development|positive regulation of ERK1 and ERK2 cascade|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|commissural neuron axon guidance|regulation of retinal ganglion cell axon guidance|sympathetic neuron projection extension|sympathetic neuron projection guidance|neural crest cell migration involved in autonomic nervous system development|semaphorin-plexin signaling pathway involved in neuron projection guidance|positive regulation of retinal ganglion cell axon guidance|VEGF-activated neuropilin signaling pathway involved in axon guidance|protein localization to early endosome|negative regulation of extrinsic apoptotic signaling pathway|,vascular endothelial growth factor-activated receptor activity|vascular endothelial growth factor-activated receptor activity|protein binding|heparin binding|semaphorin receptor activity|semaphorin receptor activity|semaphorin receptor activity|semaphorin receptor activity|growth factor binding|growth factor binding|vascular endothelial growth factor binding|vascular endothelial growth factor binding|metal ion binding|,10,0.5,1.68,10,-0.8,3.64,-0.8,3.96,-3.96,0.329,0,0,-1.9,0.6
ENSMUSG00000009471,MYOD1,myogenic differentiation 1,nuclear chromatin|nucleus|nucleus|transcription factor complex|cytoplasm|myofibril|,"regulation of alternative mRNA splicing, via spliceosome|regulation of alternative mRNA splicing, via spliceosome|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|muscle organ development|muscle organ development|myoblast fate determination|skeletal muscle tissue development|skeletal muscle tissue development|skeletal muscle tissue development|skeletal muscle tissue development|cellular response to starvation|myotube cell development|myotube differentiation involved in skeletal muscle regeneration|cell differentiation|skeletal muscle cell differentiation|skeletal muscle cell differentiation|positive regulation of skeletal muscle tissue regeneration|regulation of RNA splicing|skeletal muscle fiber adaptation|histone H3 acetylation|histone H4 acetylation|myoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|skeletal muscle fiber development|striated muscle cell differentiation|positive regulation of muscle cell differentiation|cardiac muscle cell differentiation|cellular response to glucocorticoid stimulus|cellular response to estradiol stimulus|cellular response to oxygen levels|positive regulation of myoblast fusion|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|core promoter binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|enzyme binding|chromatin DNA binding|ubiquitin protein ligase binding|nuclear hormone receptor binding|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|,10,0,0,10,1.7,6.78,1.7,3.95,3.95,0.33,0,0,0.3,3
ENSMUSG00000026768,ITGA8,integrin alpha 8,integrin complex|postsynaptic density|membrane|integral component of membrane|dendritic spine membrane|perikaryon|apical part of cell|,metanephros development|metanephros development|cell adhesion|integrin-mediated signaling pathway|multicellular organismal development|nervous system development|memory|cell projection organization|cell differentiation|extracellular matrix organization|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|inner ear morphogenesis|establishment of protein localization|smooth muscle tissue development|positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|,metal ion binding|,10,-0.5,3.76,10,-0.3,0.621,-0.5,3.95,-3.95,0.33,0,0,-1.5,0.2
ENSMUSG00000036845,LIN37,lin-37 homolog (C. elegans),cellular_component|transcriptional repressor complex|,cell cycle|biological_process|,molecular_function|,10,0.3,0.374,10,1.2,4.63,0.5,3.95,3.95,0.33,0,0,-0.1,2
ENSMUSG00000025551,FGF14,fibroblast growth factor 14,extracellular region|intracellular|nucleus|,JNK cascade|synaptic transmission|nervous system development|adult locomotory behavior|positive regulation of sodium ion transport|neuromuscular process|,receptor binding|growth factor activity|heparin binding|,10,-0.3,1.53,10,-0.6,3.29,-0.4,3.91,-3.91,0.332,0,0,-1.5,0.3
ENSMUSG00000020271,FBXW11,F-box and WD-40 domain protein 11,nucleus|cytoplasm|centrosome|cytosol|SCF ubiquitin ligase complex|SCF ubiquitin ligase complex|,"protein polyubiquitination|protein polyubiquitination|protein dephosphorylation|cell cycle|Wnt signaling pathway|protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|protein destabilization|negative regulation of NF-kappaB import into nucleus|positive regulation of circadian rhythm|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of proteolysis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|rhythmic process|",ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|protein dimerization activity|,9,-0.5,1.69,8,-0.5,2.46,-0.5,3.9,-3.9,0.333,0,0,-1.6,0.8
ENSMUSG00000018143,MAFK,"v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|",transcription regulatory region sequence-specific DNA binding|transcription cofactor binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0.3,1.64,10,1.4,4.37,0.6,3.9,3.9,0.333,0,0,-0.4,2.7
ENSMUSG00000033790,TUBGCP5,"tubulin, gamma complex associated protein 5",spindle pole|nucleus|cytoplasm|centrosome|microtubule organizing center|cytoskeleton|microtubule|gamma-tubulin ring complex|,microtubule cytoskeleton organization|microtubule nucleation|,microtubule binding|,10,-0.7,4.03,10,-0.3,0.947,-0.7,3.87,-3.87,0.335,0,0,-1.7,1.4
ENSMUSG00000026196,BARD1,BRCA1 associated RING domain 1,nucleus|nucleus|cytoplasm|BRCA1-BARD1 complex|intracellular membrane-bounded organelle|BRCA1-A complex|,DNA repair|cellular response to DNA damage stimulus|regulation of phosphorylation|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of protein export from nucleus|protein K6-linked ubiquitination|,"RNA binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein heterodimerization activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,-1,4.49,9,-0.3,0.708,-0.6,3.87,-3.87,0.335,0,0,-2,0.1
ENSMUSG00000056987,FAM71D,"family with sequence similarity 71, member D",nucleus|cytoplasm|,biological_process|,molecular_function|,9,0.8,3.63,10,0.3,2.12,0.5,3.86,3.86,0.336,0,0,-0.2,1.7
ENSMUSG00000080268,BRMS1,breast cancer metastasis-suppressor 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cellular process|negative regulation of NF-kappaB transcription factor activity|negative regulation of transcription, DNA-templated|positive regulation of protein deacetylation|positive regulation of anoikis|",protein binding|NF-kappaB binding|,10,0.2,0.312,10,1.3,6.41,1.2,3.86,3.86,0.336,0,0,-0.2,2
ENSMUSG00000049940,PGRMC2,progesterone receptor membrane component 2,membrane|membrane|integral component of membrane|,biological_process|,steroid binding|protein binding|lipid binding|heme binding|,10,0.4,1.95,10,1.2,3.03,0.5,3.86,3.86,0.336,0,0,-0.1,2
ENSMUSG00000021094,DHRS7,dehydrogenase/reductase (SDR family) member 7,membrane|,biological_process|metabolic process|oxidation-reduction process|,"oxidoreductase activity|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|versicolorin reductase activity|ketoreductase activity|",10,0.7,4.37,10,-0.3,1.19,0.6,3.85,3.85,0.336,0,0,-0.5,1.7
ENSMUSG00000032310,CYP1A2,"cytochrome P450, family 1, subfamily a, polypeptide 2",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,steroid catabolic process|cellular aromatic compound metabolic process|porphyrin-containing compound metabolic process|toxin biosynthetic process|toxin metabolic process|post-embryonic development|alkaloid metabolic process|regulation of gene expression|monoterpenoid metabolic process|drug metabolic process|drug metabolic process|dibenzo-p-dioxin metabolic process|lung development|monocarboxylic acid metabolic process|drug catabolic process|exogenous drug catabolic process|cellular respiration|heterocycle metabolic process|hydrogen peroxide biosynthetic process|oxidation-reduction process|oxidation-reduction process|oxidative demethylation|cellular response to cadmium ion|oxidative deethylation|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|enzyme binding|heme binding|demethylase activity|caffeine oxidase activity|metal ion binding|aromatase activity|",10,1.4,6.65,10,0.2,0.558,1.4,3.84,3.84,0.337,0,0,0,2.8
ENSMUSG00000063428,DDO,D-aspartate oxidase,peroxisome|,aspartate metabolic process|aspartate catabolic process|insemination|grooming behavior|D-amino acid catabolic process|D-amino acid catabolic process|hormone metabolic process|oxidation-reduction process|oxidation-reduction process|,"D-amino-acid oxidase activity|receptor binding|D-aspartate oxidase activity|D-aspartate oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor|cofactor binding|cofactor binding|",10,-0.1,0.248,10,2.3,7.04,2.3,3.83,3.83,0.338,0,0,0.1,4
ENSMUSG00000033335,DNM2,dynamin 2,nucleus|cytoplasm|Golgi apparatus|cytoskeleton|microtubule|plasma membrane|membrane|cell junction|protein complex|synapse|postsynaptic membrane|clathrin-coated endocytic vesicle|extracellular vesicular exosome|,endocytosis|receptor-mediated endocytosis|receptor internalization|transferrin transport|,nucleotide binding|GTPase activity|protein binding|GTP binding|hydrolase activity|protein kinase binding|protein complex binding|,8,0.7,2.34,6,0.8,1.79,0.7,3.83,3.83,0.338,0,0,-0.3,2
ENSMUSG00000031103,ELF4,E74-like factor 4 (ets domain transcription factor),nucleus|nucleus|PML body|,"natural killer cell proliferation|NK T cell proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,1,1.25,10,0.5,3.45,0.5,3.83,3.83,0.338,0,0,-0.1,1.7
ENSMUSG00000058258,IDI1,isopentenyl-diphosphate delta isomerase,mitochondrion|peroxisome|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|isoprenoid biosynthetic process|sterol biosynthetic process|,magnesium ion binding|isopentenyl-diphosphate delta-isomerase activity|hydrolase activity|isomerase activity|manganese ion binding|metal ion binding|,9,0.8,6.45,9,-0.5,1.82,0.7,3.82,3.82,0.338,0,0,-1.6,1.8
ENSMUSG00000026510,TRP53BP2,transformation related protein 53 binding protein 2,nucleus|cytoplasm|perinuclear region of cytoplasm|,apoptotic process|cell cycle|central nervous system development|heart development|embryo development ending in birth or egg hatching|response to ionizing radiation|intrinsic apoptotic signaling pathway by p53 class mediator|,SH3 domain binding|identical protein binding|NF-kappaB binding|,10,0.3,0.703,10,-1.1,6.08,-1.1,3.8,-3.8,0.34,0,0,-2,0.3
ENSMUSG00000038612,MCL1,myeloid cell leukemia sequence 1,nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial matrix|cytosol|membrane|membrane|integral component of membrane|Bcl-2 family protein complex|,apoptotic process|multicellular organismal development|intrinsic apoptotic signaling pathway in response to DNA damage|apoptotic mitochondrial changes|cell differentiation|response to cytokine|regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|extrinsic apoptotic signaling pathway in absence of ligand|extrinsic apoptotic signaling pathway in absence of ligand|execution phase of apoptosis|negative regulation of anoikis|regulation of response to DNA damage stimulus|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of intrinsic apoptotic signaling pathway|,protein binding|protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|BH domain binding|BH3 domain binding|BH3 domain binding|,10,0,0,10,1.2,5.1,0.7,3.8,3.8,0.34,0,0,0,2
ENSMUSG00000031824,6430548M08RIK,RIKEN cDNA 6430548M08 gene,cellular_component|,biological_process|,molecular_function|,10,0.7,1.51,10,0.9,2.67,0.8,3.79,3.79,0.34,0,0,-0.1,1.8
ENSMUSG00000031603,FGF20,fibroblast growth factor 20,extracellular region|,positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|cell differentiation|regulation of cardiac muscle cell proliferation|inner ear receptor cell differentiation|positive regulation of ERK1 and ERK2 cascade|,receptor binding|fibroblast growth factor receptor binding|growth factor activity|,10,-0.4,5.45,10,0.1,0.00986,-0.4,3.79,-3.79,0.34,0,0,-1.5,0.4
ENSMUSG00000002900,LAMB1,laminin B1,extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basement membrane|basal lamina|laminin-1 complex|laminin-1 complex|laminin-2 complex|extracellular space|extracellular matrix|laminin complex|laminin-8 complex|laminin-10 complex|laminin-10 complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,cell adhesion|negative regulation of cell adhesion|embryo implantation|learning or memory|cell migration|neuronal-glial interaction involved in cerebral cortex radial glia guided migration|positive regulation of cell migration|neuron projection development|neuron projection development|substrate adhesion-dependent cell spreading|odontogenesis|,integrin binding|extracellular matrix structural constituent|protein binding|enzyme binding|glycosphingolipid binding|,10,-0.4,5.31,9,0.1,0.139,-0.3,3.77,-3.77,0.342,0,0,-1.4,0.7
ENSMUSG00000020883,FBXL20,F-box and leucine-rich repeat protein 20,cellular_component|cytoplasm|,behavioral fear response|,protein binding|,9,1,5.95,9,-0.1,0.134,-0.5,3.76,-3.76,0.342,0,0,-1.1,2
ENSMUSG00000030750,NSMCE1,non-SMC element 1 homolog (S. cerevisiae),"chromosome, telomeric region|nucleus|chromosome|cytoplasm|Smc5-Smc6 complex|intracellular membrane-bounded organelle|",DNA repair|DNA recombination|cellular response to DNA damage stimulus|protein ubiquitination|intracellular signal transduction|positive regulation of response to DNA damage stimulus|,"ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.6,2.99,9,-0.3,1.22,0.6,3.73,3.73,0.345,0,0,-0.5,1.7
ENSMUSG00000058239,USF2,upstream transcription factor 2,nucleus|nucleus|,"positive regulation of transcription from RNA polymerase II promoter by glucose|positive regulation of transcription from RNA polymerase II promoter by glucose|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|lactation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|lipid homeostasis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|bHLH transcription factor binding|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|,10,0.3,1.43,10,0.6,3.06,0.5,3.73,3.73,0.345,0,0,-0.8,1.5
ENSMUSG00000017776,CRK,v-crk sarcoma virus CT10 oncogene homolog (avian),cytoplasm|plasma membrane|actin cytoskeleton|membrane|extracellular vesicular exosome|,positive regulation of signal transduction|phosphorylation|regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|regulation of actin cytoskeleton organization|regulation of Rac protein signal transduction|ephrin receptor signaling pathway|,"SH3/SH2 adaptor activity|protein binding|kinase activity|transferase activity|protein domain specific binding|protein binding, bridging|SH2 domain binding|protein phosphorylated amino acid binding|ephrin receptor binding|ephrin receptor binding|",10,0.8,5.59,10,-0.3,0.853,0.7,3.72,3.72,0.345,0,0,-0.4,1.9
ENSMUSG00000021114,ATP6V1D,"ATPase, H+ transporting, lysosomal V1 subunit D",lysosomal membrane|centrosome|cilium|membrane|vacuolar proton-transporting V-type ATPase complex|extracellular vesicular exosome|,transport|ion transport|proton transport|cell projection organization|cilium assembly|protein localization to cilium|,"ATPase activity, coupled to transmembrane movement of substances|",10,0.6,4.18,10,0.2,0.863,0.5,3.71,3.71,0.346,0,0,-0.5,1.7
ENSMUSG00000032285,DNAJA4,"DnaJ (Hsp40) homolog, subfamily A, member 4",cytosol|membrane|,protein folding|response to heat|protein refolding|negative regulation of inclusion body assembly|,ATP binding|heat shock protein binding|metal ion binding|unfolded protein binding|chaperone binding|,10,0.8,3.4,10,1,0.737,0.9,3.67,3.67,0.349,0,0,0,1.9
ENSMUSG00000066513,KLK1B4,kallikrein 1-related pepidase b4,intracellular|nucleus|,proteolysis|small GTPase mediated signal transduction|positive regulation of phosphatidylinositol 3-kinase activity|,catalytic activity|serine-type endopeptidase activity|receptor signaling protein activity|growth factor activity|metal ion binding|,10,-0.5,4.31,10,-0.1,0.0332,-0.4,3.66,-3.66,0.35,0,0,-1.7,0.5
ENSMUSG00000026686,LMX1A,LIM homeobox transcription factor 1 alpha,nucleus|,"regulation of cell growth|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|axon guidance|central nervous system development|brain development|regulation of gene expression|dentate gyrus development|cerebellum development|hippocampus development|central nervous system neuron differentiation|neuron differentiation|midbrain development|negative regulation of neuron differentiation|dopaminergic neuron differentiation|",DNA binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.6,2.35,10,-0.4,1.64,-0.4,3.65,-3.65,0.35,0,0,-1.7,0.3
ENSMUSG00000028172,TACR3,tachykinin receptor 3,nucleus|cytoplasm|plasma membrane|membrane|integral component of membrane|dendrite membrane|neuronal cell body membrane|,signal transduction|G-protein coupled receptor signaling pathway|tachykinin receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|positive regulation of heart rate|response to estradiol|regulation of dopamine metabolic process|response to cocaine|hyperosmotic salinity response|positive regulation of blood pressure|regulation of feeding behavior|positive regulation of uterine smooth muscle contraction|,signal transducer activity|G-protein coupled receptor activity|tachykinin receptor activity|,10,1.1,6.6,10,0,0,1.1,3.65,3.65,0.35,0,0,-0.2,2
ENSMUSG00000038416,CDC16,CDC16 cell division cycle 16,nucleus|anaphase-promoting complex|cytoplasm|centrosome|spindle microtubule|,cell cycle|mitotic nuclear division|cell division|protein K11-linked ubiquitination|,protein binding|,6,-1.1,3.5,4,-0.5,1.21,-1,3.63,-3.63,0.352,0,0,-2,1.3
ENSMUSG00000016918,SULF1,sulfatase 1,extracellular space|endoplasmic reticulum|Golgi apparatus|plasma membrane|cell surface|membrane raft|,kidney development|negative regulation of endothelial cell proliferation|chondrocyte development|glomerular filtration|sulfur compound metabolic process|apoptotic process|metabolic process|positive regulation vascular endothelial growth factor production|esophagus smooth muscle contraction|negative regulation of angiogenesis|positive regulation of Wnt signaling pathway|heparan sulfate proteoglycan metabolic process|heparan sulfate proteoglycan metabolic process|negative regulation of cell migration|positive regulation of BMP signaling pathway|glomerular basement membrane development|glial cell-derived neurotrophic factor receptor signaling pathway|regulation of fibroblast growth factor receptor signaling pathway|negative regulation of fibroblast growth factor receptor signaling pathway|negative regulation of fibroblast growth factor receptor signaling pathway|negative regulation of fibroblast growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|embryonic skeletal system development|cartilage development|bone development|innervation|negative regulation of prostatic bud formation|,catalytic activity|arylsulfatase activity|calcium ion binding|N-acetylglucosamine-6-sulfatase activity|N-acetylglucosamine-6-sulfatase activity|sulfuric ester hydrolase activity|hydrolase activity|alkyl sulfatase activity|endosulfan hemisulfate sulfatase activity|endosulfan sulfate hydrolase activity|metal ion binding|,10,-0.7,6.44,10,0.1,0.181,-0.6,3.62,-3.62,0.353,0,0,-1.8,0.4
ENSMUSG00000038914,DIDO1,death inducer-obliterator 1,nucleus|cytoplasm|cytoskeleton|,"transcription, DNA-templated|apoptotic process|apoptotic signaling pathway|",zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0.6,4.98,10,0.1,0.0388,0.6,3.61,3.61,0.353,0,0,-0.1,1.6
ENSMUSG00000054612,MGMT,O-6-methylguanine-DNA methyltransferase,nucleus|membrane|,DNA repair|DNA dealkylation involved in DNA repair|DNA dealkylation involved in DNA repair|cellular response to DNA damage stimulus|methylation|regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of DNA repair|negative regulation of cell death|,DNA binding|catalytic activity|methylated-DNA-[protein]-cysteine S-methyltransferase activity|calcium ion binding|methyltransferase activity|transferase activity|metal ion binding|,10,-0.8,3.42,10,1.6,6.29,-0.5,3.61,-3.61,0.353,0,0,-1.3,2.9
ENSMUSG00000022235,CMBL,carboxymethylenebutenolidase-like (Pseudomonas),cytoplasm|extracellular vesicular exosome|,biological_process|,molecular_function|nuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,0.9,3.94,10,-0.2,0.765,0.9,3.61,3.61,0.353,0,0,-0.4,1.9
ENSMUSG00000041577,PRELP,proline arginine-rich end leucine-rich repeat,extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular vesicular exosome|,cell aging|,extracellular matrix structural constituent|heparin binding|,10,1.4,6.43,10,0,0,1.4,3.6,3.6,0.354,0,0,0.1,3
ENSMUSG00000028549,ITGB3BP,integrin beta 3 binding protein (beta3-endonexin),"chromosome, centromeric region|kinetochore|nucleus|chromosome|","transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cell cycle|mitotic nuclear division|integrin-mediated signaling pathway|centromere-specific nucleosome assembly|cell division|",molecular_function|,9,0.4,1.77,9,0.5,2.09,0.4,3.6,3.6,0.354,0,0,-1.1,1.6
ENSMUSG00000026021,SUMO1,SMT3 suppressor of mif two 3 homolog 1 (yeast),fibrillar center|nucleus|nucleus|nucleolus|cytoplasm|membrane|nuclear body|PML body|PML body|PML body|dendrite|nuclear membrane|synapse|,"regulation of transcription, DNA-templated|response to stress|protein sumoylation|protein sumoylation|protein sumoylation|PML body organization|positive regulation of protein complex assembly|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of DNA binding|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|palate development|protein localization to nuclear pore|",protein binding|transcription factor binding|SUMO ligase activity|ubiquitin protein ligase binding|poly(A) RNA binding|,10,-0.4,3.65,10,-0.7,0.242,-0.5,3.6,-3.6,0.354,0,0,-1.7,0.1
ENSMUSG00000006599,GTF2H1,"general transcription factor II H, polypeptide 1",core TFIIH complex|nucleus|nucleus|holo TFIIH complex|,"ATP catabolic process|DNA repair|nucleotide-excision repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|cellular response to DNA damage stimulus|positive regulation of transcription from RNA polymerase II promoter|",protein kinase activity|DNA-dependent ATPase activity|RNA polymerase II carboxy-terminal domain kinase activity|,9,1.5,6.2,10,0.2,0.692,1.5,3.57,3.57,0.357,0,0,0.1,2.9
ENSMUSG00000026125,PRSS39,"protease, serine 39",extracellular region|cytoplasmic vesicle|,proteolysis|,catalytic activity|serine-type endopeptidase activity|,10,0.5,1.04,10,0.3,3,0.4,3.57,3.57,0.357,0,0,-0.3,1.4
ENSMUSG00000019866,AIM1,absent in melanoma 1,cellular_component|,biological_process|,molecular_function|,10,1,0.949,10,1.1,2.86,1,3.56,3.56,0.357,0,0,-0.1,2
ENSMUSG00000020737,HN1,hematological and neurological expressed sequence 1,cellular_component|nucleus|,biological_process|,molecular_function|,10,0.4,1.17,10,0.4,2.6,0.4,3.55,3.55,0.358,0,0,-0.5,1.8
ENSMUSG00000038429,USP5,ubiquitin specific peptidase 5 (isopeptidase T),cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|protein K48-linked deubiquitination|,protein binding|peptidase activity|cysteine-type peptidase activity|omega peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|metal ion binding|,8,0.3,1.22,8,0.6,3.12,0.5,3.54,3.54,0.359,0,0,-0.8,1.6
ENSMUSG00000048701,CCDC6,coiled-coil domain containing 6,cytoplasm|cytoskeleton|,biological_process|,molecular_function|SH3 domain binding|,10,0.3,0.645,10,-1.3,5.92,-1.2,3.54,-3.54,0.359,0,0,-2.7,0.6
ENSMUSG00000028907,UTP11L,"UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)",extracellular space|nucleus|nucleolus|nucleolus|cytoplasm|small-subunit processome|,rRNA processing|nervous system development|ribosomal small subunit biogenesis|positive regulation of apoptotic process|,poly(A) RNA binding|,9,0.2,0.874,10,0.9,3.84,0.5,3.54,3.54,0.359,0,0,-1,1.8
ENSMUSG00000029466,ANAPC7,anaphase promoting complex subunit 7,nucleus|anaphase-promoting complex|,cell cycle|mitotic nuclear division|cell division|protein K11-linked ubiquitination|,protein phosphatase binding|,10,0.3,1.38,10,0.4,2.44,0.4,3.53,3.53,0.36,0,0,-0.7,1.4
ENSMUSG00000068394,CEP152,centrosomal protein 152,nucleus|cytoplasm|centrosome|cytoskeleton|deuterosome|,centriole replication|cell projection organization|centrosome duplication|de novo centriole assembly|,protein binding|protein kinase binding|,10,0.8,0.761,10,0.4,3.16,0.4,3.53,3.53,0.36,0,0,-0.3,1.6
ENSMUSG00000031132,CD40LG,CD40 ligand,extracellular region|extracellular space|cell|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,positive regulation of immune response to tumor cell|inflammatory response|immune response|signal transduction|platelet activation|B cell differentiation|positive regulation of B cell proliferation|positive regulation of interferon-gamma production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|B cell proliferation|negative regulation of apoptotic process|isotype switching|positive regulation of MHC class II biosynthetic process|immunoglobulin secretion|regulation of immunoglobulin secretion|dendritic cell differentiation|positive regulation of endothelial cell apoptotic process|,cytokine activity|tumor necrosis factor receptor binding|CD40 receptor binding|,10,-0.8,2.49,10,-0.3,2.01,-0.5,3.52,-3.52,0.36,0,0,-1.7,0.1
ENSMUSG00000001524,GTF2H4,"general transcription factor II H, polypeptide 4",core TFIIH complex|nucleus|holo TFIIH complex|,"ATP catabolic process|DNA repair|nucleotide-excision repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|cellular response to DNA damage stimulus|",ATP-dependent DNA helicase activity|protein kinase activity|DNA-dependent ATPase activity|RNA polymerase II carboxy-terminal domain kinase activity|,9,0.2,1.85,9,0.3,1.91,0.3,3.52,3.52,0.36,0,0,-1.8,1.1
ENSMUSG00000020423,BTG2,"B cell translocation gene 2, anti-proliferative",extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein methylation|cellular response to DNA damage stimulus|negative regulation of cell proliferation|associative learning|anterior/posterior pattern specification|negative regulation of translation|dentate gyrus development|central nervous system neuron development|neuron differentiation|neuron projection development|skeletal muscle cell differentiation|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|negative regulation of neural precursor cell proliferation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|protein binding|,10,-0.4,5.11,10,0.1,0.17,-0.3,3.52,-3.52,0.36,0,0,-1.6,0.5
ENSMUSG00000021998,LCP1,lymphocyte cytosolic protein 1,stress fiber|ruffle|ruffle|phagocytic cup|extracellular space|cytoplasm|cytoplasm|cytosol|cytoskeleton|actin filament|actin filament|actin filament|plasma membrane|focal adhesion|actin cytoskeleton|membrane|cell junction|filopodium|actin filament bundle|cell projection|extracellular vesicular exosome|,T cell activation involved in immune response|response to wounding|protein kinase A signaling|cell migration|regulation of intracellular protein transport|actin filament bundle assembly|actin filament bundle assembly|,actin binding|calcium ion binding|protein binding|identical protein binding|metal ion binding|actin filament binding|actin filament binding|,10,0.1,0.0618,10,1.8,6.64,1.7,3.47,3.47,0.364,0,0,-0.1,3
ENSMUSG00000095620,2010005H15RIK,RIKEN cDNA 2010005H15 gene,cornified envelope|extracellular space|nucleus|cytoplasm|extracellular vesicular exosome|,negative regulation of endopeptidase activity|,"protease binding|cysteine-type endopeptidase inhibitor activity|structural molecule activity|protein binding, bridging|",9,1,3.31,9,0.5,1.69,0.5,3.45,3.45,0.366,0,0,-0.4,2
ENSMUSG00000038965,UBE2L3,ubiquitin-conjugating enzyme E2L 3,nucleus|cytoplasm|extracellular vesicular exosome|,"protein polyubiquitination|regulation of transcription, DNA-templated|cell proliferation|protein ubiquitination|protein K11-linked ubiquitination|cellular response to steroid hormone stimulus|cellular response to glucocorticoid stimulus|",transcription coactivator activity|ubiquitin-protein transferase activity|ubiquitin protein ligase binding|poly(A) RNA binding|,6,-0.4,2.73,6,1.1,2.6,-0.3,3.44,-3.44,0.366,0,0,-1.2,2
ENSMUSG00000024028,TFF2,trefoil factor 2 (spasmolytic protein 1),extracellular region|extracellular space|intracellular|extracellular vesicular exosome|,positive regulation of cell proliferation|positive regulation of cell proliferation|calcium-mediated signaling|regulation of cell migration|negative regulation of macrophage activation|negative regulation of inflammatory response|negative regulation of gastric acid secretion|chemokine-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade|,CXCR4 chemokine receptor binding|,9,0.7,3.09,10,0.3,1.47,0.3,3.43,3.43,0.367,0,0,-0.5,1.7
ENSMUSG00000024660,INCENP,inner centromere protein,"chromosome, centromeric region|chromosome, centromeric region|chromosome, centromeric region|kinetochore|synaptonemal complex|lateral element|central element|nucleus|chromosome|centromeric heterochromatin|cytoplasm|spindle|cytoskeleton|microtubule|chromocenter|midbody|protein complex|",cytokinesis|cell cycle|chromosome segregation|mitotic nuclear division|cell division|,None,7,0.8,4.93,7,-0.2,0.51,0.7,3.43,3.43,0.367,0,0,-1.8,1.7
ENSMUSG00000058147,XLR3C,X-linked lymphocyte-regulated 3C,cellular_component|,biological_process|,molecular_function|,3,0.4,0.758,3,1,3.34,1,3.41,3.41,0.369,0,0,-1.5,2
ENSMUSG00000073617,HDAC4,histone deacetylase 4,histone deacetylase complex|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|cytosol|cytosol|transcriptional repressor complex|sarcomere|Z disc|neuromuscular junction|A band|actomyosin|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|skeletal system development|osteoblast development|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|protein deacetylation|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of myotube differentiation|regulation of cardiac muscle contraction by calcium ion signaling|response to denervation involved in regulation of muscle adaptation|chromatin modification|histone deacetylation|positive regulation of protein sumoylation|peptidyl-lysine deacetylation|response to drug|regulation of protein binding|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of osteoblast differentiation|negative regulation of glycolytic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of skeletal muscle fiber development|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of striated muscle cell differentiation|response to interleukin-1|histone H3 deacetylation|histone H4 deacetylation|",core promoter binding|DNA binding|transcription corepressor activity|histone deacetylase activity|protein binding|transcription factor binding|transcription factor binding|zinc ion binding|hydrolase activity|protein kinase binding|potassium ion binding|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|protein deacetylase activity|protein deacetylase activity|activating transcription factor binding|histone deacetylase activity (H4-K16 specific)|histone deacetylase binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|repressing transcription factor binding|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,0.5,1.25,10,0.4,2.37,0.4,3.36,3.36,0.372,0,0,-0.2,1.9
ENSMUSG00000026526,FH1,fumarate hydratase 1,cytoplasm|mitochondrion|mitochondrion|tricarboxylic acid cycle enzyme complex|extracellular vesicular exosome|,tricarboxylic acid cycle|fumarate metabolic process|malate metabolic process|homeostasis of number of cells within a tissue|,catalytic activity|fumarate hydratase activity|lyase activity|,9,0.9,2.97,9,0.6,1.1,0.7,3.36,3.36,0.372,0,0,-0.7,2
ENSMUSG00000000149,GNA12,"guanine nucleotide binding protein, alpha 12",intracellular|heterotrimeric G-protein complex|heterotrimeric G-protein complex|membrane|brush border membrane|brush border membrane|,in utero embryonic development|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|small GTPase mediated signal transduction|Rho protein signal transduction|regulation of cell shape|regulation of fibroblast migration|cell differentiation|regulation of TOR signaling|regulation of TOR signaling|regulation of proteasomal ubiquitin-dependent protein catabolic process|regulation of proteasomal ubiquitin-dependent protein catabolic process|intracellular signal transduction|embryonic digit morphogenesis|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|GTPase activity|signal transducer activity|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|D5 dopamine receptor binding|D5 dopamine receptor binding|metal ion binding|,10,0.7,2.44,10,1.5,2.82,1,3.35,3.35,0.373,0,0,0,2.8
ENSMUSG00000026478,LAMC1,"laminin, gamma 1",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basement membrane|basal lamina|laminin-1 complex|extracellular matrix|extracellular matrix|laminin-10 complex|extracellular vesicular exosome|,protein complex assembly|cell adhesion|cell migration|extracellular matrix disassembly|neuron projection development|hemidesmosome assembly|substrate adhesion-dependent cell spreading|,extracellular matrix structural constituent|protein binding|glycosphingolipid binding|,10,-0.5,2.36,10,-0.3,1.47,-0.4,3.33,-3.33,0.375,0,0,-1.5,0.3
ENSMUSG00000034674,TDG,thymine DNA glycosylase,nucleus|nucleus|plasma membrane|PML body|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|DNA repair|base-excision repair|base-excision repair|mismatch repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|metabolic process|embryo development|chromatin modification|negative regulation of protein binding|negative regulation of chromatin binding|regulation of gene expression, epigenetic|DNA demethylation|DNA demethylation|","RNA polymerase II transcription cofactor activity|double-stranded DNA binding|protein kinase C binding|protein binding|transcription factor binding|pyrimidine-specific mismatch base pair DNA N-glycosylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hydrolase activity, hydrolyzing N-glycosyl compounds|DNA N-glycosylase activity|DNA N-glycosylase activity|protein domain specific binding|mismatched DNA binding|SUMO binding|protein homodimerization activity|structure-specific DNA binding|",10,-0.3,2.44,10,-0.2,1.12,-0.3,3.33,-3.33,0.375,0,0,-1.3,0.5
ENSMUSG00000032030,CUL5,cullin 5,nucleus|cytoplasm|plasma membrane|cullin-RING ubiquitin ligase complex|Cul5-RING ubiquitin ligase complex|,ubiquitin-dependent protein catabolic process|cytosolic calcium ion homeostasis|,protein binding|ubiquitin protein ligase binding|protein heterodimerization activity|,10,0.4,2.06,10,0.4,1.49,0.4,3.33,3.33,0.375,0,0,-0.5,1.5
ENSMUSG00000021945,ZMYM2,"zinc finger, MYM-type 2",nucleus|PML body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",protein binding|zinc ion binding|ubiquitin conjugating enzyme binding|metal ion binding|,10,0.5,4.46,10,0.1,0.0647,0.3,3.33,3.33,0.375,0,0,-0.3,1.5
ENSMUSG00000051469,ZFP191,zinc finger protein 191,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|myelination|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|metal ion binding|,10,-0.3,2.42,10,-0.3,1.12,-0.3,3.32,-3.32,0.376,0,0,-1.5,0.6
ENSMUSG00000016524,IL19,interleukin 19,extracellular region|extracellular space|,apoptotic process|interleukin-6 biosynthetic process|reactive oxygen species metabolic process|positive regulation of apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|positive regulation of intrinsic apoptotic signaling pathway|,cytokine activity|,10,-0.7,5.36,10,0.1,0.471,-0.6,3.31,-3.31,0.376,0,0,-1.8,0.3
ENSMUSG00000033282,RPGRIP1L,Rpgrip1-like,cytoplasm|centrosome|centrosome|cytoskeleton|cell-cell junction|tight junction|cilium|axoneme|cell junction|ciliary basal body|ciliary basal body|cell projection|,in utero embryonic development|kidney development|liver development|establishment or maintenance of cell polarity|determination of left/right symmetry|brain development|regulation of smoothened signaling pathway|neural tube patterning|telencephalon development|cerebellum development|lateral ventricle development|olfactory bulb development|corpus callosum development|limb morphogenesis|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|cilium assembly|camera-type eye development|nose development|negative regulation of G-protein coupled receptor protein signaling pathway|pericardium development|cilium morphogenesis|head development|,protein binding|thromboxane A2 receptor binding|,10,-0.5,3.33,10,-0.2,0.709,-0.3,3.29,-3.29,0.378,0,0,-1.5,0.4
ENSMUSG00000034201,GAS2L1,growth arrest-specific 2 like 1,stress fiber|stress fiber|cytoplasm|cytoplasm|cytoskeleton|microtubule|microtubule|,microtubule bundle formation|microtubule bundle formation|negative regulation of microtubule depolymerization|negative regulation of microtubule depolymerization|cell cycle arrest|cellular response to starvation|negative regulation of gene expression|negative regulation of gene expression|negative regulation of cell growth|negative regulation of cell growth|negative regulation of erythrocyte differentiation|negative regulation of erythrocyte differentiation|regulation of cell cycle|regulation of cell cycle|cellular response to thyroid hormone stimulus|cellular response to thyroid hormone stimulus|,microtubule binding|microtubule binding|cytoskeletal adaptor activity|cytoskeletal adaptor activity|thyroid hormone receptor binding|thyroid hormone receptor binding|,10,-0.4,0.512,10,0.3,3.09,0.3,3.28,3.28,0.379,0,0,-0.7,1.8
ENSMUSG00000024406,POU5F1,"POU domain, class 5, transcription factor 1",nucleus|nucleus|nucleus|nucleoplasm|nucleoplasm|transcription factor complex|transcription factor complex|nucleolus|cytoplasm|cytoplasm|cytosol|transcriptional repressor complex|nuclear transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|mesodermal cell fate commitment|endodermal cell fate commitment|ectodermal cell fate commitment|endodermal cell fate specification|trophectodermal cell differentiation|BMP signaling pathway involved in heart induction|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|response to organic substance|regulation of gene expression|stem cell maintenance|germ-line stem cell maintenance|response to retinoic acid|somatic stem cell maintenance|positive regulation of catenin import into nucleus|mRNA transcription from RNA polymerase II promoter|cell fate commitment|negative regulation of cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of calcium ion-dependent exocytosis|stem cell differentiation|positive regulation of SMAD protein import into nucleus|cell fate commitment involved in formation of primary germ layer|cardiac cell fate determination|negative regulation of gene silencing by miRNA|regulation of heart induction by regulation of canonical Wnt signaling pathway|regulation of methylation-dependent chromatin silencing|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription coactivator activity|DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|transcription factor binding|transcription factor binding|ubiquitin protein ligase binding|ubiquitin protein ligase binding|miRNA binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|poly(A) RNA binding|protein heterodimerization activity|POU domain binding|HMG box domain binding|,10,0.3,3.19,10,0.2,0.477,0.3,3.26,3.26,0.38,0,0,-0.4,1.4
ENSMUSG00000051615,RAP2A,RAS related protein 2a,endosome|cytosol|membrane|recycling endosome|recycling endosome|recycling endosome membrane|recycling endosome membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|negative regulation of cell migration|actin cytoskeleton reorganization|positive regulation of protein autophosphorylation|positive regulation of protein autophosphorylation|Rap protein signal transduction|cellular protein localization|establishment of protein localization|regulation of JNK cascade|regulation of dendrite morphogenesis|,nucleotide binding|GTPase activity|protein binding|GTP binding|,9,0.3,0.861,9,0.7,3.31,0.7,3.23,3.23,0.383,0,0,-0.2,1.7
ENSMUSG00000016150,TENM1,teneurin transmembrane protein 1,extracellular region|nucleus|cytoplasm|cytoskeleton|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase III promoter|response to stress|signal transduction|neuropeptide signaling pathway|positive regulation of actin filament polymerization|positive regulation of peptidyl-serine phosphorylation|positive regulation of MAP kinase activity|positive regulation of filopodium assembly|",protein homodimerization activity|protein heterodimerization activity|,10,1.2,3.82,10,0.3,1.25,1.1,3.2,3.2,0.385,0,0,-0.3,3
ENSMUSG00000073465,PARK2,"Parkinson disease (autosomal recessive, juvenile) 2, parkin",Golgi membrane|ubiquitin ligase complex|intracellular|nucleus|cytoplasm|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|synaptic vesicle|postsynaptic density|membrane|aggresome|cell junction|cytoplasmic vesicle|cell projection|neuron projection|protein complex|membrane raft|synapse|postsynaptic membrane|perinuclear region of cytoplasm|,"protein polyubiquitination|mitochondrion degradation|negative regulation of protein phosphorylation|synaptic transmission, dopaminergic|startle response|transcription, DNA-templated|regulation of transcription, DNA-templated|ubiquitin-dependent protein catabolic process|protein monoubiquitination|autophagy|response to unfolded protein|learning|locomotory behavior|cell death|adult locomotory behavior|regulation of autophagy|protein ubiquitination|protein ubiquitination|protein metabolic process|negative regulation of actin filament bundle assembly|negative regulation of glucokinase activity|synaptic transmission, glutamatergic|norepinephrine metabolic process|dopamine metabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of neuron apoptotic process|cellular protein catabolic process|negative regulation of insulin secretion|regulation of neurotransmitter secretion|regulation of synaptic transmission|dopamine uptake involved in synaptic transmission|protein autoubiquitination|negative regulation of cell death|protein K63-linked ubiquitination|aggresome assembly|protein K48-linked ubiquitination|neuron death|negative regulation of release of cytochrome c from mitochondria|negative regulation of neuron death|regulation of reactive oxygen species metabolic process|","ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|kinase binding|protein kinase binding|PDZ domain binding|ubiquitin protein ligase binding|protein complex binding|identical protein binding|ubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|chaperone binding|ubiquitin protein ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|ubiquitin-specific protease binding|",10,-0.2,0.166,10,1.5,6.13,1.5,3.2,3.2,0.385,0,0,-0.4,3
ENSMUSG00000001034,MAPK7,mitogen-activated protein kinase 7,nucleus|nucleus|cytoplasm|cytosol|cytosol|PML body|,MAPK cascade|protein phosphorylation|protein phosphorylation|cell cycle|phosphorylation|peptidyl-serine phosphorylation|cell differentiation|negative regulation of heterotypic cell-cell adhesion|positive regulation of transcription from RNA polymerase II promoter in response to stress|negative regulation of apoptotic process|regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein metabolic process|negative regulation of NFAT protein import into nucleus|negative regulation of response to cytokine stimulus|cellular response to hydrogen peroxide|cellular response to growth factor stimulus|cellular response to laminar fluid shear stress|cellular response to transforming growth factor beta stimulus|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|negative regulation of endothelial cell apoptotic process|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase binding|",10,0.3,2.42,10,0.2,1.2,0.3,3.18,3.18,0.387,0,0,-0.4,1.4
ENSMUSG00000053289,DDX10,DEAD (Asp-Glu-Ala-Asp) box polypeptide 10,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,8,0.7,3.3,10,-0.9,1.47,0.6,3.17,3.17,0.388,0,0,-1.2,1.8
ENSMUSG00000066800,RNASEL,"ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)",cytoplasm|mitochondrion|nuclear matrix|,rRNA processing|mRNA processing|protein phosphorylation|negative regulation of viral genome replication|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|RNA phosphodiester bond hydrolysis|,"nucleotide binding|RNA binding|nuclease activity|endonuclease activity|ribonuclease activity|protein kinase activity|ATP binding|bidentate ribonuclease III activity|transferase activity, transferring phosphorus-containing groups|hydrolase activity|rRNA binding|metal ion binding|",10,0.5,3,10,-0.3,2,0.4,3.17,3.17,0.388,0,0,-1,1.3
ENSMUSG00000026803,TTF1,"transcription termination factor, RNA polymerase I",nucleus|,"chromatin remodeling|transcription, DNA-templated|DNA-templated transcription, termination|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase I promoter|termination of RNA polymerase I transcription|negative regulation of DNA replication|",DNA binding|chromatin binding|protein binding|,8,0.5,4.09,8,-0.3,0.58,0.5,3.17,3.17,0.388,0,0,-0.6,1.8
ENSMUSG00000005699,PARD6A,par-6 family cell polarity regulator alpha,nucleus|cytoplasm|plasma membrane|tight junction|cell cortex|membrane|cell junction|neuronal cell body|protein complex|protein complex|axonal growth cone|apical part of cell|,cell cycle|establishment of cell polarity|cell-cell junction maintenance|cell division|regulation of cellular localization|,protein kinase C binding|protein binding|Rho GTPase binding|GTP-dependent protein binding|,10,-0.3,2.19,10,-0.2,1.27,-0.3,3.16,-3.16,0.389,0,0,-1.4,0.5
ENSMUSG00000028873,CDCA8,cell division cycle associated 8,"chromosome, centromeric region|nucleus|chromosome|nucleolus|cytoplasm|cytoskeleton|chromocenter|midbody|chromosome passenger complex|protein complex|intercellular bridge|",mitotic metaphase|cell cycle|mitotic nuclear division|chromosome organization|cell division|,protein binding|,3,0.7,1.81,4,0.5,1.57,0.6,3.14,3.14,0.39,0,0,-0.7,2
ENSMUSG00000030079,RUVBL1,RuvB-like protein 1,Swr1 complex|nucleus|cytoplasm|Golgi apparatus|ribonucleoprotein complex|Ino80 complex|NuA4 histone acetyltransferase complex|intracellular membrane-bounded organelle|protein complex|extracellular vesicular exosome|MLL1 complex|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|chromatin modification|DNA duplex unwinding|regulation of growth|histone H4 acetylation|histone H2A acetylation|cell division|",nucleotide binding|DNA helicase activity|helicase activity|ATP binding|hydrolase activity|ATP-dependent 5'-3' DNA helicase activity|,6,0.5,2.14,6,-1.2,5.61,-1.2,3.11,-3.11,0.392,0,0,-2,1.1
ENSMUSG00000047284,NEURL4,neuralized homolog 4 (Drosophila),cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,-0.2,1.16,10,-0.3,2.39,-0.3,3.11,-3.11,0.392,0,0,-1.4,0.4
ENSMUSG00000029106,ADD1,adducin 1 (alpha),nucleus|cytoplasm|cytoskeleton|plasma membrane|F-actin capping protein complex|postsynaptic density|membrane|dendrite|dendritic spine|intermediate filament cytoskeleton|synapse|perinuclear region of cytoplasm|,cell morphogenesis|in utero embryonic development|cell volume homeostasis|hemoglobin metabolic process|erythrocyte differentiation|negative regulation of actin filament polymerization|positive regulation of protein binding|multicellular organism growth|positive regulation of angiogenesis|positive regulation of endocytosis|homeostasis of number of cells within a tissue|barbed-end actin filament capping|actin filament bundle assembly|cellular response to retinoic acid|,actin binding|structural molecule activity|calmodulin binding|transcription factor binding|spectrin binding|T cell receptor binding|protein homodimerization activity|poly(A) RNA binding|protein heterodimerization activity|actin filament binding|,10,-0.1,0.19,10,-0.4,3.4,-0.4,3.07,-3.07,0.396,0,0,-1.5,0.6
ENSMUSG00000030342,CD9,CD9 antigen,extracellular space|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,cellular component movement|cell adhesion|single fertilization|fusion of sperm to egg plasma membrane|fusion of sperm to egg plasma membrane|negative regulation of cell proliferation|paranodal junction assembly|,integrin binding|protein binding|,10,-0.5,3.74,10,0,0,-0.5,3.07,-3.07,0.396,0,0,-1.5,1.2
ENSMUSG00000022243,SLC45A2,"solute carrier family 45, member 2",membrane|integral component of membrane|,visual perception|melanin biosynthetic process|developmental pigmentation|response to stimulus|,None,10,0,0,10,0.9,4.89,0.8,3.07,3.07,0.396,0,0,-0.3,1.9
ENSMUSG00000020429,IGFBP1,insulin-like growth factor binding protein 1,extracellular region|extracellular space|extracellular space|,regulation of cell growth|,insulin-like growth factor binding|growth factor binding|,10,0.8,2.34,10,0.6,1.08,0.7,3.05,3.05,0.397,0,0,-0.2,1.8
ENSMUSG00000029551,PSMG3,"proteasome (prosome, macropain) assembly chaperone 3",cellular_component|,biological_process|,molecular_function|,7,-0.7,4.91,6,0.1,0.123,-0.7,3.04,-3.04,0.398,0,0,-1.8,1.6
ENSMUSG00000028452,VCP,valosin containing protein,proteasome complex|Hrd1p ubiquitin ligase complex|nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|lipid particle|cytosol|site of double-strand break|intracellular membrane-bounded organelle|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,"ATP catabolic process|DNA repair|double-strand break repair|ubiquitin-dependent protein catabolic process|transport|ER to Golgi vesicle-mediated transport|activation of cysteine-type endopeptidase activity involved in apoptotic process|cellular response to DNA damage stimulus|protein ubiquitination|protein N-linked glycosylation via asparagine|translesion synthesis|ER-associated ubiquitin-dependent protein catabolic process|retrograde protein transport, ER to cytosol|positive regulation of protein complex assembly|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|protein hexamerization|positive regulation of protein catabolic process|protein homooligomerization|aggresome assembly|positive regulation of protein K63-linked deubiquitination|positive regulation of Lys63-specific deubiquitinase activity|",nucleotide binding|receptor binding|protein binding|ATP binding|lipid binding|hydrolase activity|ATPase activity|protein phosphatase binding|protein domain specific binding|polyubiquitin binding|polyubiquitin binding|protein complex binding|deubiquitinase activator activity|identical protein binding|ADP binding|poly(A) RNA binding|ubiquitin-specific protease binding|,3,-0.3,0.883,3,-0.6,2.61,-0.5,3.03,-3.03,0.399,0,0,-2,1
ENSMUSG00000018899,IRF1,interferon regulatory factor 1,nuclear chromatin|nucleus|nucleus|nucleus|cytoplasm|,"immune system process|regulation of adaptive immune response|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|cell cycle arrest|I-kappaB kinase/NF-kappaB signaling|regulation of gene expression|positive regulation of cell death|positive regulation of type I interferon production|positive regulation of interferon-beta production|positive regulation of natural killer cell differentiation|regulation of MyD88-dependent toll-like receptor signaling pathway|cellular response to interferon-beta|negative regulation of tyrosine phosphorylation of Stat1 protein|CD8-positive, alpha-beta T cell differentiation|positive regulation of interleukin-12 biosynthetic process|positive regulation of interleukin-12 biosynthetic process|innate immune response|regulation of innate immune response|negative regulation of regulatory T cell differentiation|positive regulation of T-helper 1 cell differentiation|negative regulation of T-helper 2 cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|defense response to virus|interferon-gamma-mediated signaling pathway|response to growth hormone|cellular response to interleukin-1|cellular response to tumor necrosis factor|cellular response to peptide hormone stimulus|regulation of CD8-positive, alpha-beta T cell proliferation|",regulatory region DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|sequence-specific DNA binding|,7,0.2,1.04,7,0.4,2.44,0.4,3.02,3.02,0.4,0,0,-0.3,1.8
ENSMUSG00000032744,HEYL,hairy/enhancer-of-split related with YRPW motif-like,nucleus|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|outflow tract morphogenesis|atrioventricular valve morphogenesis|pulmonary valve morphogenesis|epithelial to mesenchymal transition involved in endocardial cushion formation|endocardial cushion morphogenesis|cardiac ventricle morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|peripheral nervous system development|negative regulation of gene expression|mesenchymal cell development|skeletal muscle cell differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cardiac epithelial to mesenchymal transition|ventricular septum morphogenesis|negative regulation of androgen receptor signaling pathway|negative regulation of androgen receptor activity|",RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|protein binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription corepressor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|microsatellite binding|protein homodimerization activity|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|AF-1 domain binding|,10,0.5,2.42,10,0.2,1.34,0.4,3.01,3.01,0.401,0,0,-1,1.5
ENSMUSG00000014355,ANAPC1,anaphase promoting complex subunit 1,nucleus|anaphase-promoting complex|,cell cycle|mitotic nuclear division|cell division|protein K11-linked ubiquitination|,protein binding|,10,-0.5,2.09,10,0.7,4.54,0.5,2.98,2.98,0.404,0,0,-1.2,1.6
ENSMUSG00000090035,GALNT4,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4,Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,None,"polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",9,-0.4,3.44,10,0.7,2.64,-0.3,2.98,-2.98,0.404,0,0,-1.4,1.5
ENSMUSG00000027944,HAX1,HCLS1 associated X-1,nucleus|transcription factor complex|cytoplasm|mitochondrion|mitochondrion|endoplasmic reticulum|actin cytoskeleton|membrane|apical plasma membrane|sarcoplasmic reticulum|lamellipodium|clathrin-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|,cell surface receptor signaling pathway|positive regulation of phosphatidylinositol 3-kinase signaling|regulation of actin filament polymerization|positive regulation of granulocyte differentiation|positive regulation of peptidyl-serine phosphorylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of protein kinase B signaling|cellular response to cytokine stimulus|positive regulation of actin cytoskeleton reorganization|,protein binding|protein domain specific binding|interleukin-1 binding|protein N-terminus binding|,10,-1.2,5.71,10,-0.1,0.0985,-1.1,2.95,-2.95,0.406,0,0,-2,0.1
ENSMUSG00000022034,ESCO2,establishment of cohesion 1 homolog 2 (S. cerevisiae),chromatin|XY body|nucleus|chromosome|Golgi apparatus|chromocenter|nuclear centromeric heterochromatin|site of double-strand break|,hematopoietic progenitor cell differentiation|regulation of DNA replication|double-strand break repair|cell cycle|chromosome segregation|post-translational protein acetylation|protein localization to chromatin|,"dihydrolipoamide branched chain acyltransferase activity|lysine N-acetyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|metal ion binding|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.1,0.0724,10,-0.9,5.7,-0.9,2.95,-2.95,0.406,0,0,-2,0.6
ENSMUSG00000060733,IPMK,inositol polyphosphate multikinase,nucleus|,neural tube formation|phosphorylation|inositol phosphate biosynthetic process|,"nucleotide binding|inositol-1,4,5-trisphosphate 6-kinase activity|inositol tetrakisphosphate 3-kinase activity|ATP binding|inositol-1,4,5-trisphosphate 3-kinase activity|kinase activity|transferase activity|",10,-1,2.48,10,1.2,2.13,1.1,2.95,2.95,0.406,0,0,-1.2,2
ENSMUSG00000045328,CENPE,centromere protein E,"chromosome, centromeric region|kinetochore|kinetochore|condensed nuclear chromosome kinetochore|condensed chromosome, centromeric region|condensed chromosome outer kinetochore|cell|nucleus|chromosome|cytoplasm|cytoskeleton|kinesin complex|microtubule|microtubule cytoskeleton|membrane|",microtubule-based movement|cell cycle|mitotic nuclear division|regulation of mitosis|mitotic spindle assembly checkpoint|multicellular organismal development|metabolic process|attachment of spindle microtubules to kinetochore|attachment of spindle microtubules to kinetochore|establishment of protein localization|positive regulation of mitotic metaphase/anaphase transition|positive regulation of protein kinase activity|positive regulation of protein kinase activity|regulation of developmental process|cell division|positive regulation of chromosome segregation|positive regulation of attachment of spindle microtubules to kinetochore|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|protein kinase binding|kinetochore binding|kinetochore binding|,10,0.9,4.44,10,-0.2,0.448,0.5,2.89,2.89,0.412,0,0,-0.5,1.9
ENSMUSG00000064289,TANK,TRAF family member-associated Nf-kappa B activator,intracellular|cytoplasm|,I-kappaB kinase/NF-kappaB signaling|,protein binding|ubiquitin protein ligase binding|metal ion binding|,9,-0.2,0.501,9,-0.5,2.62,-0.5,2.86,-2.86,0.414,0,0,-1.7,0.3
ENSMUSG00000040599,MIS12,MIS12 homolog (yeast),"MIS12/MIND type complex|chromosome, centromeric region|kinetochore|nucleus|chromosome|",cell cycle|chromosome segregation|mitotic nuclear division|cell division|kinetochore assembly|,molecular_function|,8,-1.4,4.91,7,1.3,4.53,1.2,2.84,2.84,0.416,0,0,-2.3,2
ENSMUSG00000010755,CARS,cysteinyl-tRNA synthetase,cytoplasm|cytosol|,translation|tRNA aminoacylation for protein translation|cysteinyl-tRNA aminoacylation|cysteinyl-tRNA aminoacylation|,tRNA binding|nucleotide binding|aminoacyl-tRNA ligase activity|cysteine-tRNA ligase activity|cysteine-tRNA ligase activity|ATP binding|ligase activity|protein homodimerization activity|metal ion binding|,9,0.4,1.17,9,0.4,1.86,0.4,2.82,2.82,0.418,0,0,-1.5,1.4
ENSMUSG00000091896,UBE2D2A,ubiquitin-conjugating enzyme E2D 2A,ubiquitin ligase complex|protein complex|,protein polyubiquitination|protein ubiquitination|protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|,9,0.3,2.4,9,0.3,0.601,0.3,2.82,2.82,0.418,0,0,-0.3,1.8
ENSMUSG00000058325,DOCK1,dedicator of cytokinesis 1,nucleus|cytoplasm|membrane|,hematopoietic progenitor cell differentiation|phagocytosis|apoptotic process|small GTPase mediated signal transduction|cell migration|,guanyl-nucleotide exchange factor activity|protein binding|SH3 domain binding|,9,0.7,3.25,9,0.2,0.504,0.3,2.82,2.82,0.418,0,0,-0.3,1.7
ENSMUSG00000026790,ODF2,outer dense fiber of sperm tails 2,nucleus|cytoplasm|centrosome|centriole|centriole|cytoskeleton|microtubule|cilium|cell projection|,multicellular organismal development|spermatogenesis|cell differentiation|,structural constituent of cytoskeleton|,9,0.2,0.257,9,-1.4,5.68,-1.4,2.81,-2.81,0.419,0,0,-3,0.2
ENSMUSG00000020808,FAM64A,"family with sequence similarity 64, member A",nucleus|nucleolus|cytoplasm|,cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,9,0.3,1.71,9,-0.9,2.94,0.3,2.79,2.79,0.421,0,0,-1.6,1.5
ENSMUSG00000040354,MARS,methionine-tRNA synthetase,nucleolus|cytoplasm|mitochondrion|membrane|extracellular vesicular exosome|,translation|tRNA aminoacylation for protein translation|methionyl-tRNA aminoacylation|rRNA transcription|,tRNA binding|nucleotide binding|RNA binding|aminoacyl-tRNA ligase activity|methionine-tRNA ligase activity|ATP binding|ligase activity|,7,-0.5,1.54,7,1.1,3.18,0.4,2.78,2.78,0.422,0,0,-0.8,2
ENSMUSG00000040586,OFD1,oral-facial-digital syndrome 1 gene homolog (human),nucleus|cytoplasm|centrosome|centriole|centriole|cytoskeleton|cilium|cilium|microtubule cytoskeleton|membrane|centriolar satellite|ciliary basal body|ciliary basal body|cell projection|,embryonic body morphogenesis|cell projection organization|axoneme assembly|cilium morphogenesis|cilium morphogenesis|epithelial cilium movement involved in determination of left/right asymmetry|negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation|,alpha-tubulin binding|gamma-tubulin binding|,10,1.2,5.16,10,0,0,0.3,2.75,2.75,0.425,0,0,-0.1,2.9
ENSMUSG00000032193,LDLR,low density lipoprotein receptor,lysosome|endosome|early endosome|late endosome|Golgi apparatus|plasma membrane|caveola|coated pit|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|low-density lipoprotein particle|receptor complex|recycling endosome membrane|,lipid metabolic process|transport|lipid transport|endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|steroid metabolic process|cholesterol metabolic process|positive regulation of triglyceride biosynthetic process|regulation of phosphatidylcholine catabolic process|phospholipid transport|intestinal cholesterol absorption|cholesterol transport|cholesterol transport|low-density lipoprotein particle clearance|low-density lipoprotein particle clearance|lipoprotein metabolic process|lipoprotein catabolic process|lipoprotein catabolic process|cholesterol homeostasis|cholesterol homeostasis|cholesterol homeostasis|cholesterol import|regulation of cholesterol homeostasis|,glycoprotein binding|low-density lipoprotein receptor activity|low-density lipoprotein receptor activity|low-density lipoprotein receptor activity|calcium ion binding|protein binding|low-density lipoprotein particle binding|very-low-density lipoprotein particle receptor activity|very-low-density lipoprotein particle receptor activity|,10,-0.5,2.77,10,-0.2,0.73,-0.4,2.75,-2.75,0.425,0,0,-1.7,0.5
ENSMUSG00000030092,CNTN6,contactin 6,plasma membrane|membrane|anchored component of membrane|,cell adhesion|Notch signaling pathway|,protein binding|,10,-1.4,0.778,10,-1.4,2.14,-1.4,2.73,-2.73,0.427,0,0,-3,0.8
ENSMUSG00000017344,VTN,vitronectin,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|extracellular matrix|extracellular vesicular exosome|blood microparticle|,immune response|cell adhesion|cell-matrix adhesion|cell-matrix adhesion|positive regulation of cell-substrate adhesion|negative regulation of endopeptidase activity|positive regulation of smooth muscle cell migration|extracellular matrix organization|positive regulation of protein binding|cell adhesion mediated by integrin|positive regulation of receptor-mediated endocytosis|positive regulation of peptidyl-tyrosine phosphorylation|smooth muscle cell-matrix adhesion|,scavenger receptor activity|integrin binding|heparin binding|polysaccharide binding|extracellular matrix binding|,10,-1.2,3.42,10,-0.3,0.909,-0.5,2.73,-2.73,0.427,0,0,-2.5,0.2
ENSMUSG00000035278,PLEKHJ1,"pleckstrin homology domain containing, family J member 1",cellular_component|,biological_process|,molecular_function|,10,0.4,1.46,10,0.3,1.54,0.3,2.73,2.73,0.427,0,0,-0.4,1.5
ENSMUSG00000025142,ASPSCR1,"alveolar soft part sarcoma chromosome region, candidate 1 (human)",nucleus|cytoplasm|cytosol|cytoplasmic side of plasma membrane|vesicle membrane|membrane|extrinsic component of membrane|perinuclear region of cytoplasm|,intracellular protein transport|glucose homeostasis|regulation of glucose import|,protein binding|,10,-0.4,1.64,10,-0.3,1.28,-0.4,2.72,-2.72,0.428,0,0,-1.5,0.7
ENSMUSG00000029664,TFPI2,tissue factor pathway inhibitor 2,extracellular region|nucleus|,blood coagulation|hemostasis|negative regulation of peptidase activity|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.5,1.77,10,0.7,1.27,0.6,2.71,2.71,0.428,0,0,-0.2,1.8
ENSMUSG00000044167,FOXO1,forkhead box O1,nucleus|nucleus|cytoplasm|cytoplasm|cytosol|,"negative regulation of transcription from RNA polymerase II promoter|blood vessel development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|apoptotic process|cellular response to DNA damage stimulus|insulin receptor signaling pathway|cellular response to starvation|positive regulation of autophagy|cellular response to insulin stimulus|negative regulation of stress-activated MAPK cascade|cellular response to oxidative stress|regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter|regulation of cell proliferation|glucose homeostasis|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of fat cell differentiation|positive regulation of gluconeogenesis|positive regulation of protein catabolic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cellular response to hyperoxia|cellular response to nitric oxide|regulation of RNA biosynthetic process|",transcription factor binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|ubiquitin protein ligase binding|sequence-specific DNA binding|sequence-specific DNA binding|protein phosphatase 2A binding|,10,-0.4,4.44,10,0,0,-0.3,2.71,-2.71,0.428,0,0,-1.5,0.8
ENSMUSG00000000782,TCF7,"transcription factor 7, T cell specific",nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|brain development|Wnt signaling pathway|neural tube development|embryonic genitalia morphogenesis|T cell receptor V(D)J recombination|regulation of cell proliferation|canonical Wnt signaling pathway involved in negative regulation of apoptotic process|alpha-beta T cell differentiation|embryonic digestive tract morphogenesis|embryonic hindgut morphogenesis|generation of neurons|canonical Wnt signaling pathway|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|beta-catenin binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,-0.3,1.62,10,-0.3,1.27,-0.3,2.69,-2.69,0.43,0,0,-1.5,0.7
ENSMUSG00000025326,UBE3A,ubiquitin protein ligase E3A,proteasome complex|nucleus|cytoplasm|cytosol|,ovarian follicle development|ubiquitin-dependent protein catabolic process|positive regulation of phosphatidylinositol 3-kinase signaling|protein ubiquitination|androgen receptor signaling pathway|sperm entry|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of transcription from RNA polymerase II promoter|protein autoubiquitination|prostate gland growth|protein K48-linked ubiquitination|regulation of RNA biosynthetic process|,"transcription coactivator activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1.5,1.31,9,-0.5,3,-0.4,2.69,-2.69,0.43,0,0,-1.4,2.6
ENSMUSG00000025364,PA2G4,proliferation-associated 2G4,nucleus|nucleolus|cytoplasm|membrane|ribonucleoprotein complex|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|regulation of translation|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|RNA binding|hydrolase activity|ubiquitin protein ligase binding|poly(A) RNA binding|,10,0.5,3.06,10,0.2,0.113,0.5,2.67,2.67,0.432,0,0,-0.3,1.7
ENSMUSG00000041567,SERPINA12,"serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12",extracellular region|extracellular space|plasma membrane|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|positive regulation of phosphatidylinositol 3-kinase signaling|regulation of proteolysis|negative regulation of gluconeogenesis|positive regulation of insulin receptor signaling pathway|negative regulation of lipid biosynthetic process|regulation of cholesterol metabolic process|regulation of triglyceride metabolic process|,serine-type endopeptidase inhibitor activity|protein binding|peptidase inhibitor activity|,10,-0.5,1.72,10,-0.3,1.29,-0.3,2.66,-2.66,0.433,0,0,-1.5,0.8
ENSMUSG00000029640,USP12,ubiquitin specific peptidase 12,None,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|,cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0.5,2.39,10,0.2,0.599,0.3,2.65,2.65,0.434,0,0,-0.6,1.5
ENSMUSG00000016757,TTLL12,"tubulin tyrosine ligase-like family, member 12",cellular_component|,cellular protein modification process|biological_process|,molecular_function|,10,-0.5,4.32,10,0.2,1.51,-0.4,2.62,-2.62,0.437,0,0,-1.7,0.6
ENSMUSG00000036815,DPP10,dipeptidylpeptidase 10,membrane|integral component of membrane|,proteolysis|,serine-type peptidase activity|,9,0.6,4.32,9,0,0,0.5,2.62,2.62,0.437,0,0,-1.4,1.7
ENSMUSG00000027719,ADAD1,adenosine deaminase domain containing 1 (testis specific),nucleus|,RNA processing|multicellular organismal development|spermatogenesis|spermatid development|cell differentiation|,RNA binding|adenosine deaminase activity|,10,0.2,0.0595,10,1,3.08,0.7,2.62,2.62,0.437,0,0,0,2
ENSMUSG00000045382,CXCR4,chemokine (C-X-C motif) receptor 4,lysosome|endosome|early endosome|late endosome|plasma membrane|cell-cell junction|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cell junction|growth cone|cell leading edge|cytoplasmic vesicle|extracellular vesicular exosome|,patterning of blood vessels|ameboidal cell migration|neuron migration|neuron migration|epithelial cell development|chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|germ cell development|nervous system development|brain development|motor neuron axon guidance|germ cell migration|organ morphogenesis|cell migration|calcium-mediated signaling|telencephalon cell migration|regulation of cell migration|regulation of cell migration|T cell proliferation|neutrophil activation|regulation of programmed cell death|myelin maintenance|positive regulation of oligodendrocyte differentiation|regulation of chemotaxis|regulation of calcium ion transport|cardiac muscle contraction|chemokine-mediated signaling pathway|cellular response to cytokine stimulus|,actin binding|signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|drug binding|C-X-C chemokine receptor activity|cytokine binding|ubiquitin protein ligase binding|myosin light chain binding|ubiquitin binding|,10,-0.2,0.437,10,-0.6,2.94,-0.5,2.6,-2.6,0.439,0,0,-1.7,1
ENSMUSG00000047501,CLDN4,claudin 4,plasma membrane|integral component of plasma membrane|tight junction|tight junction|basal plasma membrane|membrane|integral component of membrane|apical plasma membrane|apicolateral plasma membrane|lateral plasma membrane|cell junction|,establishment of skin barrier|,structural molecule activity|protein binding|,10,-0.6,4.6,10,0,0,-0.5,2.6,-2.6,0.439,0,0,-1.8,0.2
ENSMUSG00000035024,NCAPD3,"non-SMC condensin II complex, subunit D3",condensed chromosome|nuclear condensin complex|nucleus|membrane|nuclear centromeric heterochromatin|germinal vesicle|,cell cycle|mitotic nuclear division|mitotic chromosome condensation|chromosome condensation|cell division|,methylated histone binding|,9,-1,1.9,10,0.5,1.74,-1,2.59,-2.59,0.44,0,0,-2,2.2
ENSMUSG00000032228,TCF12,transcription factor 12,nuclear chromatin|nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|positive regulation of gene expression|cell differentiation|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|cAMP response element binding|bHLH transcription factor binding|transcription regulatory region DNA binding|SMAD binding|protein heterodimerization activity|protein dimerization activity|E-box binding|HMG box domain binding|,10,-1,2.93,10,-0.2,1.54,-0.2,2.57,-2.57,0.442,0,0,-1.9,0.3
ENSMUSG00000004151,ETV1,ets variant 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|axon guidance|muscle organ development|mechanosensory behavior|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.5,3.91,9,-0.1,0.0357,-0.4,2.57,-2.57,0.442,0,0,-1.7,0.5
ENSMUSG00000058571,GPC6,glypican 6,extracellular region|proteinaceous extracellular matrix|nucleus|plasma membrane|integral component of plasma membrane|membrane|anchored component of membrane|,cell migration|,heparan sulfate proteoglycan binding|,10,0.5,3.32,10,0.1,0.235,0.5,2.56,2.56,0.443,0,0,-0.2,1.7
ENSMUSG00000023964,CALCR,calcitonin receptor,acrosomal vesicle|plasma membrane|cilium|membrane|integral component of membrane|axon|neuron projection|neuronal cell body|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration|protein transport|negative regulation of ossification|osteoclast differentiation|positive regulation of cAMP biosynthetic process|receptor internalization|regulation of mRNA stability|positive regulation of adenylate cyclase activity|response to glucocorticoid|protein localization to plasma membrane|,signal transducer activity|receptor activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcitonin receptor activity|calcitonin receptor activity|protein transporter activity|calcitonin binding|,10,-0.9,5.45,10,0,0,-0.7,2.56,-2.56,0.443,0,0,-2,0.1
ENSMUSG00000060601,NR1H2,"nuclear receptor subfamily 1, group H, member 2",nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of gene expression|negative regulation of gene expression|positive regulation of triglyceride biosynthetic process|positive regulation of cholesterol efflux|positive regulation of cholesterol efflux|positive regulation of cholesterol efflux|positive regulation of lipid storage|negative regulation of cholesterol storage|intracellular receptor signaling pathway|positive regulation of cellular protein metabolic process|negative regulation of lipid transport|positive regulation of cholesterol transport|cholesterol homeostasis|steroid hormone mediated signaling pathway|cellular lipid metabolic process|positive regulation of fatty acid biosynthetic process|negative regulation of proteolysis|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|retinoic acid receptor signaling pathway|negative regulation of pinocytosis|positive regulation of lipoprotein lipase activity|lipid homeostasis|positive regulation of high-density lipoprotein particle assembly|positive regulation of pancreatic juice secretion|positive regulation of secretion of lysosomal enzymes|regulation of cholesterol homeostasis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|zinc ion binding|apolipoprotein A-I receptor binding|sequence-specific DNA binding|metal ion binding|retinoid X receptor binding|retinoid X receptor binding|ATPase binding|,10,0.3,0.859,10,0.8,2.43,0.3,2.55,2.55,0.444,0,0,-0.5,1.7
ENSMUSG00000096743,VMN2R32,"vomeronasal 2, receptor 32",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,2,-0.3,0.443,2,-0.8,2.77,-0.7,2.5,-2.5,0.449,0,0,-2,1.1
ENSMUSG00000028410,DNAJA1,"DnaJ (Hsp40) homolog, subfamily A, member 1",cytosol|membrane|extracellular vesicular exosome|,"protein folding|spermatogenesis|response to heat|sperm motility|androgen receptor signaling pathway|DNA damage response, detection of DNA damage|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of JUN kinase activity|regulation of protein transport|protein localization to mitochondrion|",ATP binding|Hsp70 protein binding|heat shock protein binding|metal ion binding|low-density lipoprotein particle receptor binding|unfolded protein binding|chaperone binding|,9,0.6,1.84,10,0.5,1.06,0.6,2.5,2.5,0.449,0,0,-0.3,1.8
ENSMUSG00000025929,IL17A,interleukin 17A,extracellular region|extracellular space|extracellular space|external side of plasma membrane|,inflammatory response|positive regulation of interleukin-23 production|positive regulation of osteoclast differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cellular response to interleukin-1|cellular response to glucocorticoid stimulus|fibroblast activation|positive regulation of cytokine production involved in inflammatory response|positive regulation of cytokine production involved in inflammatory response|,cytokine activity|,10,-0.4,1.14,10,0.4,1.93,0.3,2.44,2.44,0.455,0,0,-1,1.4
ENSMUSG00000045095,MAGI1,"membrane associated guanylate kinase, WW and PDZ domain containing 1",nucleus|cytoplasm|plasma membrane|tight junction|membrane|cell junction|cell projection|,neuron death|,nucleotide binding|protein binding|ATP binding|alpha-actinin binding|,10,0.8,0.76,10,1.4,2.64,1.2,2.44,2.44,0.455,0,0,-0.6,2
ENSMUSG00000031841,CDH13,cadherin 13,extracellular space|cytoplasm|plasma membrane|plasma membrane|caveola|external side of plasma membrane|membrane|integral component of membrane|anchored component of membrane|neuron projection|perinuclear region of cytoplasm|extracellular vesicular exosome|,regulation of cell growth|positive regulation of endothelial cell proliferation|positive regulation of cell-matrix adhesion|sprouting angiogenesis|cell adhesion|homophilic cell adhesion|negative regulation of cell adhesion|Rho protein signal transduction|negative regulation of cell proliferation|calcium-dependent cell-cell adhesion|Rac protein signal transduction|lamellipodium assembly|regulation of endocytosis|positive regulation of cell migration|regulation of epidermal growth factor receptor signaling pathway|endothelial cell migration|keratinocyte proliferation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle cell proliferation|positive regulation of calcium-mediated signaling|positive regulation of positive chemotaxis|localization within membrane|low-density lipoprotein particle mediated signaling|,calcium ion binding|protein binding|low-density lipoprotein particle binding|protein homodimerization activity|cadherin binding|metal ion binding|adiponectin binding|lipoprotein particle binding|,10,-0.3,1.34,10,-0.4,1.34,-0.3,2.44,-2.44,0.455,0,0,-1.5,0.8
ENSMUSG00000021277,TRAF3,TNF receptor-associated factor 3,cytoplasm|endosome|cytoplasmic side of plasma membrane|CD40 receptor complex|,regulation of cytokine production|toll-like receptor signaling pathway|immune system process|apoptotic process|signal transduction|Toll signaling pathway|protein ubiquitination|regulation of proteolysis|regulation of proteolysis|regulation of proteolysis|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB transcription factor activity|regulation of interferon-beta production|tumor necrosis factor-mediated signaling pathway|tumor necrosis factor-mediated signaling pathway|regulation of apoptotic process|innate immune response|regulation of defense response to virus|,"ubiquitin-protein transferase activity|tumor necrosis factor receptor binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein kinase binding|ubiquitin protein ligase binding|thioesterase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,3.3,10,0.6,2.92,-0.7,2.43,-2.43,0.456,0,0,-1.9,2.1
ENSMUSG00000036390,GADD45A,growth arrest and DNA-damage-inducible 45 alpha,nucleus|nucleus|nucleus|cytoplasm|,activation of MAPKKK activity|negative regulation of protein kinase activity|response to stress|cellular response to DNA damage stimulus|cell cycle|cell cycle arrest|centrosome cycle|signal transduction in response to DNA damage|positive regulation of apoptotic process|positive regulation of JNK cascade|regulation of cell cycle|cellular response to ionizing radiation|positive regulation of p38MAPK cascade|positive regulation of reactive oxygen species metabolic process|,core promoter binding|protein binding|,10,0.7,1.82,10,0.3,0.883,0.3,2.43,2.43,0.456,0,0,-0.2,1.8
ENSMUSG00000007570,FANCE,"Fanconi anemia, complementation group E",Fanconi anaemia nuclear complex|,biological_process|,molecular_function|,10,-1.1,2.01,10,-0.5,2.42,-0.6,2.4,-2.4,0.46,0,0,-1.9,0.4
ENSMUSG00000040669,PHC1,polyhomeotic-like 1 (Drosophila),sex chromatin|nucleus|nucleus|nuclear body|PcG protein complex|PRC1 complex|,multicellular organismal development|histone ubiquitination|cellular response to retinoic acid|,DNA binding|chromatin binding|protein binding|zinc ion binding|metal ion binding|,10,-1,3.67,10,1.5,5.6,1.5,2.4,2.4,0.46,0,0,-1.4,3
ENSMUSG00000027829,CCNL1,cyclin L1,nucleus|cytoplasm|transcription elongation factor complex|nuclear speck|,"regulation of cyclin-dependent protein serine/threonine kinase activity|transcription, DNA-templated|regulation of transcription, DNA-templated|RNA processing|",protein binding|protein kinase binding|,10,-1,3.33,10,1.5,3.3,-0.3,2.4,-2.4,0.46,0,0,-1.7,2.6
ENSMUSG00000032680,6820408C15RIK,RIKEN cDNA 6820408C15 gene,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.44,10,-0.9,0.422,-0.8,2.38,-2.38,0.462,0,0,-2,0.7
ENSMUSG00000031004,MKI67,antigen identified by monoclonal antibody Ki 67,"chromosome, centromeric region|condensed chromosome|intracellular|nucleus|nucleus|nucleolus|nucleolus|cytoplasm|membrane|",meiotic nuclear division|cell proliferation|,protein C-terminus binding|poly(A) RNA binding|,10,-0.4,2.5,10,-0.1,0.263,-0.3,2.38,-2.38,0.462,0,0,-1.7,0.8
ENSMUSG00000033712,CCAR2,cell cycle activator and apoptosis regulator 2,nuclear chromatin|nucleus|spliceosomal complex|cytoplasm|mitochondrial matrix|DBIRD complex|,"regulation of transcription, DNA-templated|mRNA processing|apoptotic process|cellular response to DNA damage stimulus|cell cycle|RNA splicing|response to UV|regulation of DNA-templated transcription, elongation|positive regulation of apoptotic process|negative regulation of catalytic activity|negative regulation of catalytic activity|mitochondrial fragmentation involved in apoptotic process|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of DNA damage checkpoint|",RNA polymerase II core binding|enzyme inhibitor activity|enzyme inhibitor activity|enzyme binding|poly(A) RNA binding|,10,0,0,10,0.9,4.9,0.9,2.32,2.32,0.468,0,0,-0.1,1.9
ENSMUSG00000035382,PCSK7,proprotein convertase subtilisin/kexin type 7,Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,proteolysis|protein processing|protein processing|,serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,1.1,2.55,10,-0.4,2.58,-0.4,2.31,-2.31,0.469,0,0,-1,2
ENSMUSG00000032959,PEBP1,phosphatidylethanolamine binding protein 1,extracellular space|nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|rough endoplasmic reticulum|Golgi apparatus|synaptic vesicle|cell surface|cell surface|neuron projection|neuronal cell body|axon terminus|apical part of cell|extracellular vesicular exosome|,MAPK cascade|regulation of neurotransmitter levels|negative regulation of protein phosphorylation|regulation of the force of heart contraction|negative regulation of peptidase activity|negative regulation of MAPK cascade|positive regulation of cAMP-mediated signaling|positive regulation of mitosis|sperm capacitation|positive regulation of acetylcholine metabolic process|,nucleotide binding|serine-type endopeptidase inhibitor activity|receptor binding|ATP binding|lipid binding|enzyme binding|kinase binding|protein kinase binding|peptidase inhibitor activity|poly(A) RNA binding|mitogen-activated protein kinase binding|,10,1.6,1.16,10,0.7,3.21,0.8,2.3,2.3,0.47,0,0,-0.5,2.7
ENSMUSG00000025588,NAT1,N-acetyl transferase 1,cytoplasm|cytosol|,metabolic process|,"arylamine N-acetyltransferase activity|arylamine N-acetyltransferase activity|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.9,3.28,10,0.3,0.579,0.4,2.29,2.29,0.471,0,0,-0.3,1.9
ENSMUSG00000019803,NR2E1,"nuclear receptor subfamily 2, group E, member 1",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|behavioral fear response|aggressive behavior|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|brain development|visual perception|positive regulation of cell proliferation|glial cell migration|dentate gyrus development|amygdala development|olfactory bulb development|layer formation in cerebral cortex|forebrain generation of neurons|cerebral cortex neuron differentiation|anterior commissure morphogenesis|cerebral cortex development|extracellular matrix organization|somatic stem cell maintenance|social behavior|camera-type eye development|negative regulation of apoptotic process|steroid hormone mediated signaling pathway|cell fate commitment|negative regulation of neuron differentiation|positive regulation of angiogenesis|positive regulation of cell cycle|positive regulation of transcription from RNA polymerase II promoter|negative regulation of astrocyte differentiation|regulation of dendrite morphogenesis|regulation of cellular component organization|retina development in camera-type eye|regulation of timing of neuron differentiation|long-term synaptic potentiation|regulation of cell migration involved in sprouting angiogenesis|negative regulation of neural precursor cell proliferation|positive regulation of neural precursor cell proliferation|positive regulation of stem cell proliferation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|protein binding|zinc ion binding|enzyme binding|histone deacetylase binding|sequence-specific DNA binding|metal ion binding|,10,-0.8,3.19,10,-0.2,0.543,-0.5,2.28,-2.28,0.472,0,0,-1.9,0.2
ENSMUSG00000002343,ARMC6,armadillo repeat containing 6,cellular_component|,hematopoietic progenitor cell differentiation|,molecular_function|,10,0.4,1.42,10,0.6,1.22,0.4,2.28,2.28,0.472,0,0,-0.3,1.8
ENSMUSG00000020689,ITGB3,integrin beta 3,nucleus|plasma membrane|focal adhesion|integrin complex|external side of plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|integrin alpha9-beta1 complex|melanosome|receptor complex|extracellular vesicular exosome|alpha9-beta1 integrin-ADAM8 complex|,positive regulation of endothelial cell proliferation|positive regulation of leukocyte migration|protein folding|cellular calcium ion homeostasis|cell-substrate junction assembly|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|multicellular organismal development|regulation of G-protein coupled receptor protein signaling pathway|positive regulation of endothelial cell migration|negative regulation of macrophage derived foam cell differentiation|positive regulation of fibroblast migration|negative regulation of lipid storage|smooth muscle cell migration|positive regulation of smooth muscle cell migration|platelet activation|regulation of cell migration|positive regulation of cell migration|cell-substrate adhesion|activation of protein kinase activity|negative regulation of lipid transport|positive regulation of cell adhesion mediated by integrin|positive regulation of osteoblast proliferation|positive regulation of MAPK cascade|positive regulation of osteoclast differentiation|negative regulation of low-density lipoprotein particle receptor biosynthetic process|positive regulation of angiogenesis|positive regulation of bone resorption|positive regulation of bone resorption|positive regulation of smooth muscle cell proliferation|cell projection morphogenesis|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of lipoprotein metabolic process|regulation of release of sequestered calcium ion into cytosol|angiogenesis involved in wound healing|negative regulation of cell death|positive regulation of ERK1 and ERK2 cascade|platelet aggregation|positive regulation of glomerular mesangial cell proliferation|positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|,protein disulfide isomerase activity|receptor activity|integrin binding|protein binding|peptide binding|identical protein binding|vascular endothelial growth factor receptor 2 binding|cell adhesion molecule binding|fibrinogen binding|,10,0,0,10,-0.4,3.64,-0.3,2.27,-2.27,0.474,0,0,-1.5,0.6
ENSMUSG00000032942,UCP3,"uncoupling protein 3 (mitochondrial, proton carrier)",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial membrane|,response to superoxide|response to superoxide|response to hypoxia|fatty acid metabolic process|transport|mitochondrial transport|proton transport|transmembrane transport|,oxidative phosphorylation uncoupler activity|,10,0.4,2.21,10,-1.4,1.28,-1.2,2.26,-2.26,0.475,0,0,-2.9,1
ENSMUSG00000021266,WARS,tryptophanyl-tRNA synthetase,nucleus|cytoplasm|extracellular vesicular exosome|,angiogenesis|translation|tRNA aminoacylation for protein translation|tryptophanyl-tRNA aminoacylation|regulation of angiogenesis|,nucleotide binding|aminoacyl-tRNA ligase activity|tryptophan-tRNA ligase activity|ATP binding|ligase activity|,9,0.6,1.37,9,0.3,1.38,0.3,2.25,2.25,0.476,0,0,-0.5,1.8
ENSMUSG00000009670,TEX11,testis expressed gene 11,condensed nuclear chromosome|synaptonemal complex|central element|chromosome|,resolution of meiotic recombination intermediates|meiotic gene conversion|male meiosis chromosome segregation|meiotic nuclear division|synaptonemal complex assembly|reciprocal meiotic recombination|male meiosis|male gonad development|fertilization|negative regulation of apoptotic process|chiasma assembly|,protein binding|,10,-0.1,0.172,10,-0.6,3.38,-0.4,2.24,-2.24,0.477,0,0,-1.7,0.5
ENSMUSG00000057228,AADAT,aminoadipate aminotransferase,mitochondrion|mitochondrion|,2-oxoglutarate metabolic process|glutamate metabolic process|biosynthetic process|tryptophan catabolic process to kynurenine|kynurenine metabolic process|L-kynurenine metabolic process|,catalytic activity|transaminase activity|kynurenine-oxoglutarate transaminase activity|transferase activity|pyridoxal phosphate binding|protein homodimerization activity|2-aminoadipate transaminase activity|,10,-0.5,3.73,10,-0.1,0.0456,-0.4,2.24,-2.24,0.477,0,0,-1.7,0.4
ENSMUSG00000042042,CSGALNACT2,chondroitin sulfate N-acetylgalactosaminyltransferase 2,Golgi apparatus|membrane|membrane|integral component of membrane|Golgi cisterna membrane|,proteoglycan biosynthetic process|chondroitin sulfate proteoglycan biosynthetic process|chondroitin sulfate proteoglycan biosynthetic process|dermatan sulfate proteoglycan biosynthetic process|,acetylgalactosaminyltransferase activity|acetylgalactosaminyltransferase activity|transferase activity|metal ion binding|glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|,10,-0.4,0.449,10,-0.3,2.03,-0.3,2.23,-2.23,0.478,0,0,-1.6,0.6
ENSMUSG00000020930,CCDC103,coiled-coil domain containing 103,cellular_component|cytoplasm|cilium|cell projection|,heart looping|cilium movement|cell projection organization|outer dynein arm assembly|inner dynein arm assembly|axonemal dynein complex assembly|determination of digestive tract left/right asymmetry|,protein homodimerization activity|,10,0.6,1.02,10,0.3,1.6,0.3,2.23,2.23,0.478,0,0,-0.7,1.7
ENSMUSG00000024590,LMNB1,lamin B1,nucleus|nuclear envelope|nuclear inner membrane|lamin filament|nucleoplasm|intermediate filament|membrane|membrane|nuclear matrix|nuclear membrane|,positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle|positive regulation of JNK cascade|,structural molecule activity|JUN kinase binding|phospholipase binding|,10,0.4,1.2,10,1.3,2.56,0.4,2.19,2.19,0.483,0,0,-0.5,2
ENSMUSG00000032451,TRIM42,tripartite motif-containing 42,cellular_component|intracellular|,biological_process|,zinc ion binding|metal ion binding|,10,0.1,0.0868,10,-0.7,3.83,-0.6,2.17,-2.17,0.485,0,0,-1.8,0.5
ENSMUSG00000071337,TIA1,cytotoxic granule-associated RNA binding protein 1,nucleus|cytoplasm|cytoplasmic stress granule|cytoplasmic stress granule|nuclear stress granule|,"apoptotic process|negative regulation of translation|negative regulation of cytokine biosynthetic process|regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|AU-rich element binding|poly(A) RNA binding|,10,-0.5,2.89,10,0.3,0.515,-0.5,2.17,-2.17,0.485,0,0,-1.7,0.8
ENSMUSG00000066440,ZFYVE26,"zinc finger, FYVE domain containing 26",cytoplasm|lysosomal membrane|centrosome|cytoskeleton|midbody|,double-strand break repair via homologous recombination|cytokinesis|DNA repair|cellular response to DNA damage stimulus|cell cycle|cell division|,lipid binding|phosphatidylinositol-3-phosphate binding|metal ion binding|,9,0.2,0.797,9,-0.3,2.47,-0.3,2.16,-2.16,0.486,0,0,-1.5,1
ENSMUSG00000018916,CSF2,colony stimulating factor 2 (granulocyte-macrophage),extracellular region|extracellular space|extracellular space|,embryonic placenta development|immune response|positive regulation of cell proliferation|regulation of gene expression|regulation of gene expression|positive regulation of gene expression|positive regulation of macrophage derived foam cell differentiation|positive regulation of interleukin-23 production|epithelial fluid transport|macrophage activation|regulation of cell proliferation|positive regulation of tyrosine phosphorylation of Stat5 protein|myeloid dendritic cell differentiation|positive regulation of DNA replication|negative regulation of cytolysis|positive regulation of podosome assembly|dendritic cell differentiation|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,cytokine activity|cytokine activity|granulocyte macrophage colony-stimulating factor receptor binding|growth factor activity|,10,-0.3,2.65,10,0,0,-0.3,2.16,-2.16,0.486,0,0,-1.7,0.6
ENSMUSG00000018217,PMP22,peripheral myelin protein 22,plasma membrane|tight junction|membrane|integral component of membrane|compact myelin|,cell cycle|cell cycle arrest|negative regulation of cell proliferation|negative regulation of neuron projection development|cell differentiation|myelin assembly|myelination|,None,10,0.5,1.92,10,0.3,0.706,0.4,2.16,2.16,0.486,0,0,-0.4,1.7
ENSMUSG00000076750,TCRG-V3,"T cell receptor gamma, variable 3",external side of plasma membrane|,None,None,4,0.4,1.95,4,0.4,0.343,0.4,2.15,2.15,0.487,0,0,-0.9,2
ENSMUSG00000023915,TNFRSF21,"tumor necrosis factor receptor superfamily, member 21",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|intrinsic component of plasma membrane|,B cell apoptotic process|adaptive immune response|immune system process|apoptotic process|humoral immune response|signal transduction|negative regulation of B cell proliferation|negative regulation of myelination|negative regulation of T cell proliferation|myelination|regulation of oligodendrocyte differentiation|T cell receptor signaling pathway|neuron apoptotic process|cellular response to tumor necrosis factor|oligodendrocyte apoptotic process|negative regulation of interleukin-5 secretion|negative regulation of interleukin-13 secretion|negative regulation of interleukin-10 secretion|,None,10,-0.5,2.71,10,-0.1,0.427,-0.3,2.14,-2.14,0.489,0,0,-1.7,0.4
ENSMUSG00000031391,L1CAM,L1 cell adhesion molecule,plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|presynaptic membrane|terminal bouton|membrane raft|,cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|cell surface receptor signaling pathway|multicellular organismal development|nervous system development|axon guidance|axon guidance|axon guidance|positive regulation of cell-cell adhesion|cell differentiation|neuron projection development|neuron projection development|cell-cell adhesion mediated by integrin|homotypic cell-cell adhesion|positive regulation of calcium-mediated signaling|,integrin binding|protein binding|PDZ domain binding|sialic acid binding|identical protein binding|protein self-association|,10,-0.4,0.694,10,-0.4,1.57,-0.4,2.11,-2.11,0.492,0,0,-1.5,1.5
ENSMUSG00000029617,CCZ1,CCZ1 vacuolar protein trafficking and biogenesis associated,cellular_component|lysosome|membrane|,biological_process|,molecular_function|,8,0,0,8,-0.7,3.48,-0.6,2.11,-2.11,0.492,0,0,-1.6,1.6
ENSMUSG00000000708,KAT2B,K(lysine) acetyltransferase 2B,histone acetyltransferase complex|kinetochore|nucleus|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|A band|I band|actomyosin|,"chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|protein acetylation|cell cycle|negative regulation of cell proliferation|regulation of protein ADP-ribosylation|histone acetylation|N-terminal peptidyl-lysine acetylation|internal peptidyl-lysine acetylation|internal peptidyl-lysine acetylation|peptidyl-lysine acetylation|cellular response to insulin stimulus|positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter|histone H3 acetylation|histone H3-K9 acetylation|negative regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|","transcription cofactor activity|transcription coactivator activity|transcription coactivator activity|histone acetyltransferase activity|histone acetyltransferase activity|lysine N-acetyltransferase activity|lysine N-acetyltransferase activity|cyclin-dependent protein serine/threonine kinase inhibitor activity|protein binding|N-acetyltransferase activity|transcription factor binding|acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein kinase binding|protein complex binding|histone deacetylase binding|",10,0.1,0.121,10,0.4,2.73,0.3,2.11,2.11,0.492,0,0,-1,1.4
ENSMUSG00000033685,UCP2,"uncoupling protein 2 (mitochondrial, proton carrier)",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial membrane|,response to superoxide|transport|mitochondrial transport|positive regulation of cell death|negative regulation of apoptotic process|negative regulation of insulin secretion involved in cellular response to glucose stimulus|,None,10,-0.4,1.17,10,-0.6,1.44,-0.4,2.1,-2.1,0.493,0,0,-1.7,0.8
ENSMUSG00000032085,TAGLN,transgelin,cytoplasm|,epithelial cell differentiation|,None,10,1,1.09,10,0.5,1.81,0.5,2.1,2.1,0.493,0,0,-0.2,2
ENSMUSG00000076745,TCRG-V4,"T cell receptor gamma, variable 4",None,None,None,10,-0.5,1.78,10,-0.3,0.725,-0.5,2.09,-2.09,0.495,0,0,-1.8,0.7
ENSMUSG00000039840,EPG5,ectopic P-granules autophagy protein 5 homolog (C. elegans),intracellular|cell|,autophagy|endocytic recycling|autophagic vacuole maturation|,molecular_function|,10,-1.1,3.09,10,-0.2,0.844,-0.3,2.08,-2.08,0.496,0,0,-2,0.3
ENSMUSG00000038037,SOCS1,suppressor of cytokine signaling 1,intracellular|nucleus|cytoplasm|cytoplasmic vesicle|,regulation of protein phosphorylation|JAK-STAT cascade|negative regulation of signal transduction|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|intracellular signal transduction|regulation of growth|negative regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of catalytic activity|fat cell differentiation|negative regulation of JAK-STAT cascade|negative regulation of insulin receptor signaling pathway|regulation of interferon-gamma-mediated signaling pathway|cellular response to amino acid stimulus|,insulin-like growth factor receptor binding|protein binding|kinase inhibitor activity|protein kinase binding|,10,0.5,0.562,10,1.5,3.95,1.5,2.08,2.08,0.496,0,0,-0.2,3
ENSMUSG00000070473,CLDN3,claudin 3,plasma membrane|tight junction|tight junction|membrane|integral component of membrane|lateral plasma membrane|cell junction|extracellular vesicular exosome|,calcium-independent cell-cell adhesion|,structural molecule activity|protein binding|identical protein binding|,10,0.8,3.15,10,0.2,0.515,0.4,2.07,2.07,0.497,0,0,-0.2,1.9
ENSMUSG00000021038,VIPAS39,"VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog",cytoplasm|endosome|early endosome|late endosome|HOPS complex|cytoplasmic vesicle|recycling endosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|intracellular protein transport|spermatogenesis|endosome to lysosome transport|protein transport|cell differentiation|",molecular_function|,10,1,4.23,10,0,0,0.6,2.07,2.07,0.497,0,0,-0.2,2
ENSMUSG00000032782,CNTROB,"centrobin, centrosomal BRCA2 interacting protein",cytoplasm|centrosome|centriole|cytoskeleton|,cytokinesis|cell cycle|centriole replication|centrosome separation|cell division|,protein domain specific binding|,10,-0.3,0.45,9,0.6,3.07,0.5,2.07,2.07,0.497,0,0,-1.5,1.6
ENSMUSG00000037440,VNN1,vanin 1,plasma membrane|membrane|integral component of membrane|anchored component of membrane|extracellular vesicular exosome|,acute inflammatory response|chronic inflammatory response|nitrogen compound metabolic process|inflammatory response|pantothenate metabolic process|single organismal cell-cell adhesion|positive regulation of T cell differentiation in thymus|innate immune response|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|pantetheine hydrolase activity|GPI anchor binding|",10,0,0,10,-0.4,3.46,-0.4,2.07,-2.07,0.497,0,0,-1.7,0.6
ENSMUSG00000004099,DNMT1,DNA methyltransferase (cytosine-5) 1,heterochromatin|nucleus|nucleus|replication fork|centromeric heterochromatin|cytoplasm|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|DNA methylation|DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|metabolic process|maintenance of DNA methylation|maintenance of DNA methylation|DNA methylation on cytosine within a CG sequence|regulation of gene expression|positive regulation of gene expression|gene silencing|chromatin modification|methylation|regulation of cell proliferation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|S-adenosylhomocysteine metabolic process|S-adenosylmethioninamine metabolic process|S-adenosylmethionine metabolic process|positive regulation of histone H3-K4 methylation|negative regulation of histone H3-K9 methylation|cellular response to amino acid stimulus|C-5 methylation of cytosine|","DNA binding|DNA binding|chromatin binding|double-stranded DNA binding|RNA binding|catalytic activity|DNA (cytosine-5-)-methyltransferase activity|DNA (cytosine-5-)-methyltransferase activity|protein binding|transcription factor binding|methyltransferase activity|zinc ion binding|methyl-CpG binding|methyl-CpG binding|DNA-methyltransferase activity|transferase activity|protein domain specific binding|histone deacetylase binding|unmethylated CpG binding|metal ion binding|DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates|",9,-0.5,3.96,8,0.2,0.806,-0.4,2.06,-2.06,0.498,0,0,-1.4,1.6
ENSMUSG00000024578,IL17B,interleukin 17B,extracellular region|extracellular space|,inflammatory response|neutrophil chemotaxis|positive regulation of cytokine production involved in inflammatory response|,receptor binding|cytokine activity|,10,0.2,0.278,10,-0.4,2.99,-0.3,2.06,-2.06,0.498,0,0,-1.6,0.8
ENSMUSG00000003604,AVEN,"apoptosis, caspase activation inhibitor",intracellular|intracellular|membrane|membrane|,apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|,molecular_function|,10,-0.2,0.706,10,-0.3,1.66,-0.2,2.05,-2.05,0.5,0,0,-1.3,1.2
ENSMUSG00000047238,MAGEH1,"melanoma antigen, family H, 1",cytoplasm|,biological_process|,molecular_function|,10,1,3.27,10,-1.1,1.23,0.3,2.04,2.04,0.501,0,0,-1.3,2
ENSMUSG00000021238,ALDH6A1,"aldehyde dehydrogenase family 6, subfamily A1",nucleus|mitochondrion|mitochondrion|extracellular vesicular exosome|,thymine catabolic process|valine metabolic process|valine catabolic process|metabolic process|beta-alanine catabolic process|thymine metabolic process|brown fat cell differentiation|oxidation-reduction process|,"methylmalonate-semialdehyde dehydrogenase (acylating) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|thiolester hydrolase activity|malonate-semialdehyde dehydrogenase (acetylating) activity|poly(A) RNA binding|",10,0.5,0.262,10,0.6,1.94,0.5,2.04,2.04,0.501,0,0,-1.7,1.4
ENSMUSG00000006736,TSPAN31,tetraspanin 31,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,2.56,10,0.1,0.231,0.5,2.04,2.04,0.501,0,0,-0.3,1.8
ENSMUSG00000020027,SOCS2,suppressor of cytokine signaling 2,intracellular|cytoplasm|,regulation of cell growth|lactation|lactation|negative regulation of signal transduction|response to estradiol|cellular response to hormone stimulus|intracellular signal transduction|regulation of growth|regulation of multicellular organism growth|negative regulation of multicellular organism growth|negative regulation of multicellular organism growth|positive regulation of neuron differentiation|negative regulation of JAK-STAT cascade|growth hormone receptor signaling pathway|mammary gland alveolus development|mammary gland alveolus development|,growth hormone receptor binding|insulin-like growth factor receptor binding|JAK pathway signal transduction adaptor activity|,10,-0.1,0.0647,10,-0.9,3.86,-0.8,2.02,-2.02,0.503,0,0,-2,0.5
ENSMUSG00000024258,POLR2D,polymerase (RNA) II (DNA directed) polypeptide D,"cytoplasmic mRNA processing body|nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|","nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|mRNA export from nucleus in response to heat stress|recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex|cellular metabolic process|positive regulation of translational initiation|",nucleotide binding|single-stranded DNA binding|single-stranded RNA binding|catalytic activity|DNA-directed RNA polymerase activity|DNA-directed RNA polymerase activity|translation initiation factor binding|,5,0.3,1.54,4,-1.3,3.89,-1.2,2.02,-2.02,0.503,0,0,-2,1.3
ENSMUSG00000056602,FRY,furry homolog (Drosophila),cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,-0.3,0.275,10,-0.5,2.01,-0.5,2.02,-2.02,0.503,0,0,-1.8,0.4
ENSMUSG00000001655,HOXC13,homeobox C13,nucleus|,"hair follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|anatomical structure morphogenesis|anterior/posterior pattern specification|nail development|tongue morphogenesis|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding|,10,0.7,1.92,10,-0.2,0.496,0.4,2.02,2.02,0.503,0,0,-0.5,1.8
ENSMUSG00000024537,PSMG2,"proteasome (prosome, macropain) assembly chaperone 2",nucleus|nucleus|,mitotic spindle assembly checkpoint|negative regulation of apoptotic process|proteasome assembly|regulation of cell cycle|,molecular_function|,8,0.5,2.16,9,0.2,0.717,0.2,2.02,2.02,0.503,0,0,-1.2,1.8
ENSMUSG00000022589,CYP11B2,"cytochrome P450, family 11, subfamily b, polypeptide 2",mitochondrion|mitochondrion|membrane|dendrite|,regulation of systemic arterial blood pressure by circulatory renin-angiotensin|regulation of blood volume by renal aldosterone|steroid biosynthetic process|C21-steroid hormone biosynthetic process|glucocorticoid biosynthetic process|regulation of blood pressure|aldosterone biosynthetic process|aldosterone biosynthetic process|cortisol biosynthetic process|drinking behavior|positive regulation of blood pressure|ion homeostasis|oxidation-reduction process|,"monooxygenase activity|steroid 11-beta-monooxygenase activity|steroid 11-beta-monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|corticosterone 18-monooxygenase activity|",10,0.5,0.931,10,0.7,1.46,0.6,2.01,2.01,0.504,0,0,-0.3,1.9
ENSMUSG00000060981,HIST1H4H,"histone cluster 1, H4h",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,9,0,0,9,0.6,3.47,0.5,2,2,0.506,0,0,-0.7,1.8
ENSMUSG00000031776,ARL2BP,ADP-ribosylation factor-like 2 binding protein,nucleus|cytoplasm|mitochondrion|mitochondrial intermembrane space|centrosome|cytoskeleton|cilium|midbody|cell projection|,positive regulation of tyrosine phosphorylation of Stat3 protein|regulation of catalytic activity|maintenance of protein location in nucleus|regulation of RNA biosynthetic process|,transcription coactivator activity|small GTPase regulator activity|protein binding|,9,-0.2,0.757,10,1.5,5.19,1.5,1.99,1.99,0.507,0,0,-0.3,3
ENSMUSG00000019428,FKBP8,FK506 binding protein 8,mitochondrion|mitochondrial envelope|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|cell fate specification|protein folding|apoptotic process|smoothened signaling pathway|smoothened signaling pathway|dorsal/ventral pattern formation|regulation of gene expression|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|neural tube development|regulation of BMP signaling pathway|positive regulation of BMP signaling pathway|multicellular organism growth|camera-type eye development|negative regulation of apoptotic process|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|isomerase activity|identical protein binding|,10,-0.3,0.268,10,-0.3,1.86,-0.3,1.99,-1.99,0.507,0,0,-1.7,0.5
ENSMUSG00000069171,NR2F1,"nuclear receptor subfamily 2, group F, member 1",nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|negative regulation of neuron projection development|cerebral cortex regionalization|forebrain development|steroid hormone mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|zinc ion binding|sequence-specific DNA binding|sequence-specific DNA binding|retinoic acid-responsive element binding|metal ion binding|,10,0.1,0.187,10,0.3,2.38,0.3,1.95,1.95,0.512,0,0,-0.6,1.6
ENSMUSG00000020720,PSMD12,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 12",proteasome complex|proteasome regulatory particle|membrane|proteasome accessory complex|extracellular vesicular exosome|,None,molecular_function|,5,0.9,3.85,5,-0.1,0.133,0.6,1.95,1.95,0.512,0,0,-0.9,2
ENSMUSG00000020312,SHC2,SHC (Src homology 2 domain containing) transforming protein 2,None,intracellular signal transduction|,None,10,0.1,0.00167,10,-0.4,2.88,-0.4,1.95,-1.95,0.512,0,0,-1.6,0.8
ENSMUSG00000001930,VWF,Von Willebrand factor homolog,extracellular region|proteinaceous extracellular matrix|endoplasmic reticulum|external side of plasma membrane|extracellular matrix|Weibel-Palade body|extracellular vesicular exosome|,liver development|placenta development|cell adhesion|blood coagulation|blood coagulation|hemostasis|hemostasis|hemostasis|platelet activation|cell-substrate adhesion|cell-substrate adhesion|protein homooligomerization|,glycoprotein binding|protease binding|integrin binding|protein binding|collagen binding|immunoglobulin binding|identical protein binding|protein homodimerization activity|protein N-terminus binding|chaperone binding|,10,-0.4,3.54,10,0.2,0.524,-0.3,1.94,-1.94,0.513,0,0,-1.4,1.3
ENSMUSG00000047454,GPHN,gephyrin,intracellular|cytoplasm|cytoskeleton|plasma membrane|membrane|extrinsic component of plasma membrane|cell junction|synapse|postsynaptic membrane|inhibitory synapse|inhibitory synapse|,Mo-molybdopterin cofactor biosynthetic process|Mo-molybdopterin cofactor biosynthetic process|establishment of synaptic specificity at neuromuscular junction|metabolic process|molybdopterin cofactor biosynthetic process|establishment of protein localization|protein homooligomerization|glycine receptor clustering|,nucleotide binding|catalytic activity|receptor binding|protein binding|ATP binding|cytoskeletal protein binding|transferase activity|protein complex scaffold|protein homodimerization activity|metal ion binding|molybdopterin adenylyltransferase activity|molybdopterin molybdotransferase activity|,10,-0.6,4.55,10,0.1,0.342,-0.5,1.94,-1.94,0.513,0,0,-1.9,0.5
ENSMUSG00000026648,DCLRE1C,"DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)",nucleus|,"telomere maintenance|DNA catabolic process, endonucleolytic|immune system process|DNA repair|double-strand break repair|DNA recombination|cellular response to DNA damage stimulus|response to ionizing radiation|B cell differentiation|chromosome organization|nucleic acid phosphodiester bond hydrolysis|",single-stranded DNA endodeoxyribonuclease activity|nuclease activity|endonuclease activity|exonuclease activity|5'-3' exonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,-0.3,0.94,10,-0.3,1.16,-0.3,1.94,-1.94,0.513,0,0,-1.8,0.5
ENSMUSG00000028859,CSF3R,colony stimulating factor 3 receptor (granulocyte),membrane|integral component of membrane|,cell adhesion|neutrophil chemotaxis|,cytokine receptor activity|,10,-0.6,1.71,10,1.2,4.37,0.6,1.93,1.93,0.515,0,0,-0.8,2
ENSMUSG00000022817,ITGB5,integrin beta 5,focal adhesion|integrin complex|membrane|integral component of membrane|cell leading edge|receptor complex|extracellular vesicular exosome|,cell adhesion|integrin-mediated signaling pathway|multicellular organismal development|,receptor activity|receptor binding|integrin binding|,10,0,0,10,-0.3,3.63,-0.2,1.92,-1.92,0.516,0,0,-1.6,0.7
ENSMUSG00000021974,FGF9,fibroblast growth factor 9,extracellular region|basement membrane|extracellular space|intracellular|cell|cytoplasm|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|angiogenesis|osteoblast differentiation|positive regulation of mesenchymal cell proliferation|positive regulation of mesenchymal cell proliferation|chondrocyte differentiation|chondrocyte differentiation|cardiac left ventricle morphogenesis|cardiac ventricle development|protein import into nucleus|cell-cell signaling|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|male gonad development|positive regulation of gene expression|cell differentiation|negative regulation of Wnt signaling pathway|male sex determination|male sex determination|lung development|lung development|embryonic limb morphogenesis|positive regulation of vascular endothelial growth factor receptor signaling pathway|inner ear morphogenesis|positive regulation of MAPK cascade|positive regulation of smoothened signaling pathway|positive regulation of smoothened signaling pathway|positive regulation of transcription, DNA-templated|regulation of timing of cell differentiation|embryonic digestive tract development|embryonic skeletal system development|positive regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|positive regulation of cell division|positive regulation of cardiac muscle cell proliferation|positive regulation of cardiac muscle cell proliferation|positive regulation of cardiac muscle cell proliferation|lung-associated mesenchyme development|vasculogenesis involved in coronary vascular morphogenesis|positive regulation of canonical Wnt signaling pathway|",receptor binding|fibroblast growth factor receptor binding|growth factor activity|heparin binding|,9,0.6,2.68,9,0.1,0.0207,0.5,1.92,1.92,0.516,0,0,-0.4,1.8
ENSMUSG00000039239,TGFB2,"transforming growth factor, beta 2",extracellular region|basement membrane|extracellular space|extracellular space|cytoplasm|endosome|trans-Golgi network|cell surface|secretory granule|axon|extracellular matrix|neuronal cell body|,cell morphogenesis|skeletal system development|cartilage condensation|blood vessel development|eye development|response to hypoxia|epithelial to mesenchymal transition|hair follicle development|hair follicle development|blood vessel remodeling|heart morphogenesis|outflow tract morphogenesis|heart valve morphogenesis|cardiac left ventricle morphogenesis|cardiac right ventricle morphogenesis|protein phosphorylation|cell cycle arrest|transforming growth factor beta receptor signaling pathway|SMAD protein import into nucleus|axon guidance|heart development|heart development|cell death|positive regulation of cell proliferation|negative regulation of cell proliferation|glial cell migration|cardioblast differentiation|positive regulation of gene expression|positive regulation of epithelial cell migration|negative regulation of alkaline phosphatase activity|positive regulation of epithelial to mesenchymal transition|negative regulation of macrophage cytokine production|positive regulation of phosphatidylinositol 3-kinase signaling|cell growth|cell migration|signal transduction by phosphorylation|hemopoiesis|extracellular matrix organization|collagen fibril organization|positive regulation of cell growth|negative regulation of cell growth|positive regulation of cell migration|hair follicle morphogenesis|activation of protein kinase activity|response to progesterone|positive regulation of stress-activated MAPK cascade|regulation of transforming growth factor beta2 production|positive regulation of cell adhesion mediated by integrin|intracellular signal transduction|growth|wound healing|dopamine biosynthetic process|response to drug|catagen|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of neuron apoptotic process|response to estrogen|cell-cell junction organization|negative regulation of keratinocyte differentiation|positive regulation of integrin biosynthetic process|positive regulation of cell cycle|positive regulation of heart contraction|somatic stem cell division|neuron fate commitment|neuron development|embryonic neurocranium morphogenesis|negative regulation of epithelial cell proliferation|positive regulation of protein secretion|negative regulation of immune response|negative regulation of release of sequestered calcium ion into cytosol|positive regulation of cell division|positive regulation of catagen|positive regulation of cardioblast differentiation|cardiac muscle cell proliferation|cardiac epithelial to mesenchymal transition|pathway-restricted SMAD protein phosphorylation|pathway-restricted SMAD protein phosphorylation|ventricular septum morphogenesis|negative regulation of cartilage development|positive regulation of activation-induced cell death of T cells|extrinsic apoptotic signaling pathway|regulation of extracellular matrix organization|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,beta-amyloid binding|receptor signaling protein serine/threonine kinase activity|receptor binding|type II transforming growth factor beta receptor binding|transforming growth factor beta receptor binding|protein binding|growth factor activity|protein homodimerization activity|protein heterodimerization activity|protein N-terminus binding|,10,-0.4,1.57,10,-0.4,0.497,-0.4,1.92,-1.92,0.516,0,0,-1.6,0.9
ENSMUSG00000063594,GNG8,"guanine nucleotide binding protein (G protein), gamma 8",heterotrimeric G-protein complex|plasma membrane|membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|,10,-1.4,5.14,10,0,0,-1.3,1.92,-1.92,0.516,0,0,-2.9,0.2
ENSMUSG00000025280,POLR3A,polymerase (RNA) III (DNA directed) polypeptide A,DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|membrane|,"transcription, DNA-templated|positive regulation of interferon-beta production|innate immune response|",RNA polymerase III activity|chromatin binding|DNA-directed RNA polymerase activity|transferase activity|nucleotidyltransferase activity|,7,0.1,0.463,8,1.4,4.08,1.4,1.92,1.92,0.516,0,0,-0.9,3
ENSMUSG00000034557,ZFYVE9,"zinc finger, FYVE domain containing 9",cytoplasm|early endosome membrane|,transforming growth factor beta receptor signaling pathway|SMAD protein complex assembly|SMAD protein import into nucleus|regulation of transforming growth factor beta receptor signaling pathway|,protein binding|1-phosphatidylinositol binding|SMAD binding|metal ion binding|,10,-0.3,1.23,10,-0.3,0.833,-0.3,1.91,-1.91,0.517,0,0,-1.7,0.8
ENSMUSG00000041684,BIVM,"basic, immunoglobulin-like variable motif containing",extracellular space|nucleus|cytoplasm|,biological_process|,molecular_function|,10,-0.1,0.289,10,-0.4,2.79,-0.3,1.91,-1.91,0.517,0,0,-1.6,0.8
ENSMUSG00000017950,HNF4A,"hepatic nuclear factor 4, alpha",nucleus|nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|ornithine metabolic process|lipid metabolic process|acyl-CoA metabolic process|xenobiotic metabolic process|establishment of tissue polarity|sex differentiation|blood coagulation|negative regulation of cell proliferation|response to glucose|response to glucose|regulation of gastrulation|regulation of lipid metabolic process|signal transduction involved in regulation of gene expression|cell differentiation|negative regulation of cell growth|regulation of microvillus assembly|negative regulation of protein import into nucleus, translocation|negative regulation of tyrosine phosphorylation of Stat5 protein|glucose homeostasis|steroid hormone mediated signaling pathway|negative regulation of sequence-specific DNA binding transcription factor activity|cell-cell junction organization|positive regulation of gluconeogenesis|positive regulation of fatty acid biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of peptidyl-tyrosine phosphorylation|regulation of insulin secretion|lipid homeostasis|phospholipid homeostasis|SMAD protein signal transduction|triglyceride homeostasis|positive regulation of cholesterol homeostasis|",fatty-acyl-CoA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II activating transcription factor binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|receptor binding|fatty acid binding|protein binding|transcription factor binding|zinc ion binding|palmitoyl-CoA hydrolase activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|repressing transcription factor binding|,10,-0.1,0.172,10,-0.3,2.35,-0.2,1.91,-1.91,0.517,0,0,-1.7,0.6
ENSMUSG00000030898,CCKBR,cholecystokinin B receptor,nucleus|cytoplasm|plasma membrane|membrane|integral component of membrane|,"gastric acid secretion|gastric acid secretion|histamine secretion|behavioral defense response|apoptotic process|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cell proliferation|positive regulation of synaptic transmission, GABAergic|digestive tract development|gland development|positive regulation of synaptic transmission|regulation of sensory perception of pain|positive regulation of synaptic transmission, glutamatergic|estrous cycle phase|ERK1 and ERK2 cascade|positive regulation of somatostatin secretion|",signal transducer activity|G-protein coupled receptor activity|protein binding|gastrin receptor activity|type B gastrin/cholecystokinin receptor binding|,10,-0.3,1.88,10,-0.1,0.345,-0.3,1.9,-1.9,0.518,0,0,-1.8,0.5
ENSMUSG00000024854,POLD4,"polymerase (DNA-directed), delta 4",nucleus|,positive regulation of endothelial cell proliferation|DNA replication|DNA-dependent DNA replication|,molecular_function|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|,10,-0.4,2.94,10,0.9,1.98,-0.3,1.89,-1.89,0.52,0,0,-1.2,1.7
ENSMUSG00000029576,RADIL,Ras association and DIL domains,microtubule|,cell adhesion|signal transduction|multicellular organismal development|substrate adhesion-dependent cell spreading|,protein binding|,10,0.3,1.13,10,0.3,0.912,0.3,1.89,1.89,0.52,0,0,-0.7,1.6
ENSMUSG00000025037,MAOA,monoamine oxidase A,mitochondrion|mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,catecholamine metabolic process|neurotransmitter catabolic process|dopamine catabolic process|serotonin metabolic process|phenylethylamine metabolic process|oxidation-reduction process|,protein binding|primary amine oxidase activity|primary amine oxidase activity|oxidoreductase activity|flavin adenine dinucleotide binding|serotonin binding|,10,0.3,0.468,10,-1.4,1.9,0.4,1.88,1.88,0.521,0,0,-2.8,1.2
ENSMUSG00000031652,N4BP1,NEDD4 binding protein 1,nucleus|nucleolus|PML body|,negative regulation of protein ubiquitination|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular response to UV|cellular response to UV|,RNA binding|protein binding|,10,-0.3,1.55,10,-0.2,0.693,-0.3,1.87,-1.87,0.522,0,0,-1.5,0.9
ENSMUSG00000022353,MTSS1,metastasis suppressor 1,cytoplasm|cytoskeleton|adherens junction|actin cytoskeleton|,in utero embryonic development|actin filament organization|signal transduction|nervous system development|muscle organ development|magnesium ion homeostasis|actin cytoskeleton organization|actin filament polymerization|bone mineralization|positive regulation of actin filament bundle assembly|adherens junction maintenance|filopodium assembly|negative regulation of epithelial cell proliferation|renal tubule morphogenesis|cellular response to fluid shear stress|renal system development|glomerulus morphogenesis|nephron tubule epithelial cell differentiation|epithelial cell proliferation involved in renal tubule morphogenesis|,actin binding|actin monomer binding|receptor binding|cytoskeletal adaptor activity|SH3 domain binding|identical protein binding|actin filament binding|,10,-0.1,0.45,10,-0.5,2.69,-0.3,1.87,-1.87,0.522,0,0,-1.7,0.8
ENSMUSG00000031546,GINS4,GINS complex subunit 4 (Sld5 homolog),nucleus|cytoplasm|,DNA replication|biological_process|,protein binding|,9,0.8,2.14,9,-0.6,0.31,-0.3,1.86,-1.86,0.524,0,0,-1.4,1.7
ENSMUSG00000015027,GALNS,galactosamine (N-acetyl)-6-sulfate sulfatase,lysosome|extracellular vesicular exosome|,metabolic process|,catalytic activity|sulfuric ester hydrolase activity|hydrolase activity|N-acetylgalactosamine-6-sulfatase activity|metal ion binding|,10,1.3,3.74,10,-0.1,0.173,-0.4,1.85,-1.85,0.525,0,0,-1.4,2.8
ENSMUSG00000037740,MRPS26,mitochondrial ribosomal protein S26,nucleus|mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,biological_process|,poly(A) RNA binding|,7,0.8,1.56,6,-0.8,3.24,-0.6,1.85,-1.85,0.525,0,0,-2,1.3
ENSMUSG00000003949,HLF,hepatic leukemia factor,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle cell differentiation|rhythmic process|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.2,0.644,10,0.2,1.34,0.2,1.84,1.84,0.526,0,0,-0.6,1.8
ENSMUSG00000030172,ERC1,ELKS/RAB6-interacting/CAST family member 1,cytoplasm|Golgi apparatus|IkappaB kinase complex|membrane|synapse|,"transport|I-kappaB phosphorylation|protein transport|retrograde transport, endosome to Golgi|",protein binding|Rab GTPase binding|PDZ domain binding|,10,0.9,1.53,10,1,0.49,0.9,1.82,1.82,0.529,0,0,-0.8,2
ENSMUSG00000013973,DEDD,death effector domain-containing,nucleus|nucleolus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of protein catabolic process|regulation of apoptotic process|decidualization|negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|",DNA binding|protein binding|,10,0.2,0.188,10,-0.4,2.42,-0.2,1.82,-1.82,0.529,0,0,-1.6,0.8
ENSMUSG00000000093,TBX2,T-box 2,nucleus|nucleus|transcription factor complex|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|heart morphogenesis|outflow tract septum morphogenesis|outflow tract morphogenesis|endocardial cushion morphogenesis|regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|muscle cell fate determination|cell aging|cell aging|positive regulation of cell proliferation|aorta morphogenesis|atrioventricular canal development|embryonic digit morphogenesis|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|embryonic camera-type eye morphogenesis|cardiac muscle tissue development|palate development|palate development|positive regulation of cardiac muscle cell proliferation|pharynx development|developmental growth involved in morphogenesis|mammary placode formation|cellular senescence|negative regulation of heart looping|negative regulation of cardiac chamber formation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.3,2.27,10,-0.1,0.136,-0.2,1.82,-1.82,0.529,0,0,-1.7,0.6
ENSMUSG00000025784,CLEC3B,"C-type lectin domain family 3, member b",granular component|extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|cytoplasm|cytoplasm|extracellular vesicular exosome|,skeletal system development|positive regulation of plasminogen activation|bone mineralization|,calcium ion binding|calcium ion binding|protein binding|heparin binding|carbohydrate binding|kringle domain binding|,10,-0.2,0.5,10,-0.4,1.99,-0.3,1.81,-1.81,0.53,0,0,-1.7,0.7
ENSMUSG00000020153,NDUFS7,NADH dehydrogenase (ubiquinone) Fe-S protein 7,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|neuron projection|neuronal cell body|respiratory chain|synaptic membrane|,transport|mitochondrial respiratory chain complex I assembly|oxidation-reduction process|,"protease binding|NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|oxidoreductase activity|metal ion binding|quinone binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",9,-0.3,1.21,8,0.9,2.12,-0.3,1.8,-1.8,0.532,0,0,-1,1.9
ENSMUSG00000030069,PROK2,prokineticin 2,extracellular region|,angiogenesis|epicardium-derived cardiac endothelial cell differentiation|chemotaxis|neuropeptide signaling pathway|spermatogenesis|circadian rhythm|cell proliferation|negative regulation of apoptotic process|positive regulation of smooth muscle contraction|rhythmic process|coronary vasculature development|vasculogenesis involved in coronary vascular morphogenesis|epicardium-derived cardiac vascular smooth muscle cell differentiation|,G-protein coupled receptor binding|G-protein coupled receptor binding|,10,-0.3,2.35,10,-0.1,0.027,-0.2,1.8,-1.8,0.532,0,0,-1.6,0.7
ENSMUSG00000022454,NELL2,NEL-like 2,extracellular region|extracellular space|cytoplasm|membrane|dendrite|perikaryon|,regulation of growth|protein homotrimerization|,protein kinase C binding|calcium ion binding|heparin binding|identical protein binding|,10,-0.5,4.31,10,1.3,2.29,-0.5,1.8,-1.8,0.532,0,0,-1.2,2
ENSMUSG00000040174,ALKBH3,"alkB, alkylation repair homolog 3 (E. coli)",nucleus|cytoplasm|,DNA repair|DNA dealkylation involved in DNA repair|cellular response to DNA damage stimulus|cell proliferation|oxidative single-stranded DNA demethylation|oxidation-reduction process|DNA demethylation|,"sulfonate dioxygenase activity|ferrous iron binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|cytosine C-5 DNA demethylase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",9,-0.3,0.363,9,0.4,2.69,0.3,1.79,1.79,0.533,0,0,-0.9,1.8
ENSMUSG00000017466,TIMP2,tissue inhibitor of metalloproteinase 2,extracellular region|basement membrane|extracellular space|cell surface|cell surface|growth cone|neuron projection|neuronal cell body|extracellular vesicular exosome|,negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of cAMP metabolic process|regulation of Rap protein signal transduction|positive regulation of catalytic activity|regulation of MAPK cascade|positive regulation of MAPK cascade|regulation of neuron differentiation|regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of adenylate cyclase activity|negative regulation of proteolysis|negative regulation of mitotic cell cycle|negative regulation of Ras protein signal transduction|cellular response to organic substance|,enzyme inhibitor activity|integrin binding|integrin binding|enzyme activator activity|metalloendopeptidase inhibitor activity|metalloendopeptidase inhibitor activity|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|metal ion binding|,10,-0.9,4.55,10,1,0.755,-0.6,1.79,-1.79,0.533,0,0,-2,1.1
ENSMUSG00000014850,MSH3,mutS homolog 3 (E. coli),nuclear chromosome|nucleus|membrane|MutSbeta complex|MutSbeta complex|,meiotic mismatch repair|ATP catabolic process|DNA repair|mismatch repair|mismatch repair|mismatch repair|cellular response to DNA damage stimulus|reciprocal meiotic recombination|somatic recombination of immunoglobulin gene segments|maintenance of DNA repeat elements|maintenance of DNA repeat elements|negative regulation of DNA recombination|positive regulation of helicase activity|,nucleotide binding|Y-form DNA binding|heteroduplex DNA loop binding|double-strand/single-strand DNA junction binding|DNA binding|damaged DNA binding|single-stranded DNA binding|ATP binding|DNA-dependent ATPase activity|centromeric DNA binding|enzyme binding|mismatched DNA binding|dinucleotide insertion or deletion binding|single guanine insertion binding|dinucleotide repeat insertion binding|,10,0.1,0.0782,10,0.3,2.31,0.3,1.79,1.79,0.533,0,0,-1.7,1.2
ENSMUSG00000029161,CGREF1,cell growth regulator with EF hand domain 1,cellular_component|extracellular region|,cell cycle|cell cycle arrest|cell adhesion|negative regulation of cell growth|,molecular_function|calcium ion binding|metal ion binding|,10,-0.2,0.692,10,0.3,3.46,0.3,1.79,1.79,0.533,0,0,-0.8,1.9
ENSMUSG00000040212,EMP3,epithelial membrane protein 3,membrane|integral component of membrane|,cell growth|,None,10,0.1,0.251,10,0.4,2.2,0.3,1.78,1.78,0.534,0,0,-0.8,1.6
ENSMUSG00000030956,FAM53B,"family with sequence similarity 53, member B",cellular_component|,biological_process|,molecular_function|,10,-1.3,0.125,10,-1,2.02,-1.2,1.77,-1.77,0.536,0,0,-2,0.4
ENSMUSG00000039989,CBX4,chromobox 4,nucleus|nucleus|nuclear body|PcG protein complex|PRC1 complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|protein sumoylation|negative regulation of transcription, DNA-templated|","chromatin binding|single-stranded RNA binding|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|enzyme binding|SUMO binding|SUMO binding|methylated histone binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|transcription regulatory region DNA binding|phosphoprotein binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.633,10,1.4,3.35,0.4,1.77,1.77,0.536,0,0,-0.1,2.8
ENSMUSG00000048482,BDNF,brain derived neurotrophic factor,extracellular region|extracellular space|cell|cytoplasm|synaptic vesicle|cytoplasmic membrane-bounded vesicle|mitochondrial crista|axon|dendrite|neuronal cell body|terminal bouton|perikaryon|perinuclear region of cytoplasm|,"ureteric bud development|behavioral fear response|mitochondrial electron transport, NADH to ubiquinone|gamma-aminobutyric acid signaling pathway|nervous system development|negative regulation of neuroblast proliferation|axon guidance|axon target recognition|learning or memory|learning|feeding behavior|neuron recognition|glutamate secretion|dendrite development|regulation of metabolic process|nerve development|regulation of axon extension|negative regulation of synaptic transmission, GABAergic|positive regulation of peptidyl-serine phosphorylation|mechanoreceptor differentiation|response to drug|fear response|negative regulation of apoptotic process|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of neuron differentiation|negative regulation of striated muscle tissue development|regulation of retinal cell programmed cell death|regulation of synaptic plasticity|regulation of long-term neuronal synaptic plasticity|positive regulation of long-term neuronal synaptic plasticity|regulation of short-term neuronal synaptic plasticity|axon extension|inner ear development|positive regulation of synapse assembly|regulation of excitatory postsynaptic membrane potential|negative regulation of cell death|taste bud development|dendrite extension|negative regulation of neuron death|neuron projection extension|",receptor binding|neurotrophin TRKB receptor binding|protein binding|growth factor activity|,10,0.2,0.626,10,1.2,2.95,0.4,1.76,1.76,0.537,0,0,-0.1,2
ENSMUSG00000037405,ICAM1,intercellular adhesion molecule 1,immunological synapse|extracellular space|plasma membrane|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|acute inflammatory response to antigenic stimulus|T cell antigen processing and presentation|positive regulation of cellular extravasation|cell adhesion|cell adhesion|leukocyte cell-cell adhesion|leukocyte cell-cell adhesion|sensory perception of sound|regulation of cell shape|single organismal cell-cell adhesion|regulation of cell adhesion|positive regulation of actin filament polymerization|positive regulation of Rho GTPase activity|cell adhesion mediated by integrin|adhesion of symbiont to host|positive regulation of nitric oxide biosynthetic process|positive regulation of vasoconstriction|receptor-mediated virion attachment to host cell|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of NF-kappaB transcription factor activity|negative regulation of calcium ion transport|establishment of endothelial barrier|positive regulation of ERK1 and ERK2 cascade|cellular response to glucose stimulus|establishment of Sertoli cell barrier|regulation of ruffle assembly|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of endothelial cell apoptotic process|,integrin binding|protein complex binding|,10,-0.2,0.551,10,0.5,2.48,0.5,1.76,1.76,0.537,0,0,-0.8,1.8
ENSMUSG00000020651,SLC26A4,"solute carrier family 26, member 4",plasma membrane|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|brush border membrane|extracellular vesicular exosome|,transport|anion transport|chloride transport|regulation of pH|sulfate transport|organ morphogenesis|inorganic anion transport|iodide transport|regulation of protein localization|ion transmembrane transport|transmembrane transport|chloride transmembrane transport|,secondary active sulfate transmembrane transporter activity|anion transmembrane transporter activity|chloride transmembrane transporter activity|iodide transmembrane transporter activity|sulfate transmembrane transporter activity|,10,-0.3,1.98,10,0,0,-0.3,1.75,-1.75,0.539,0,0,-1.8,0.4
ENSMUSG00000026229,PSMD1,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 1",proteasome complex|membrane|proteasome accessory complex|extracellular vesicular exosome|,regulation of protein catabolic process|,protein binding|enzyme regulator activity|,9,0.6,2.7,9,0,0,0.5,1.74,1.74,0.54,0,0,-0.5,1.8
ENSMUSG00000028456,UNC13B,unc-13 homolog B (C. elegans),cytoplasm|Golgi apparatus|cytosol|membrane|cell junction|neuromuscular junction|synapse|,"exocytosis|signal transduction|synaptic transmission|neuromuscular junction development|synaptic vesicle docking involved in exocytosis|synaptic vesicle priming|synaptic transmission, glutamatergic|synaptic transmission, glutamatergic|intracellular signal transduction|regulation of short-term neuronal synaptic plasticity|innervation|",non-kinase phorbol ester receptor activity|diacylglycerol binding|metal ion binding|,10,0,0,10,0.4,2.51,0.3,1.74,1.74,0.54,0,0,-0.5,1.8
ENSMUSG00000046093,HPCAL4,hippocalcin-like 4,intracellular|,biological_process|,calcium channel regulator activity|calcium ion binding|protein C-terminus binding|protein domain specific binding|metal ion binding|,10,0.3,0.931,10,0.2,0.986,0.3,1.74,1.74,0.54,0,0,-0.6,1.7
ENSMUSG00000052593,ADAM17,a disintegrin and metallopeptidase domain 17,extracellular region|cytoplasm|cytoplasm|plasma membrane|integral component of plasma membrane|cell-cell junction|focal adhesion|cell surface|actin cytoskeleton|membrane|membrane|integral component of membrane|apical plasma membrane|ruffle membrane|membrane raft|,response to hypoxia|positive regulation of protein phosphorylation|germinal center formation|proteolysis|membrane protein ectodomain proteolysis|membrane protein ectodomain proteolysis|cell adhesion|epidermal growth factor receptor signaling pathway|Notch signaling pathway|Notch receptor processing|integrin-mediated signaling pathway|positive regulation of cell proliferation|positive regulation of T cell chemotaxis|B cell differentiation|positive regulation of cell growth|positive regulation of cell migration|positive regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|response to lipopolysaccharide|negative regulation of interleukin-8 production|positive regulation of chemokine production|regulation of mast cell apoptotic process|T cell differentiation in thymus|cell adhesion mediated by integrin|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway|response to drug|negative regulation of apoptotic process|positive regulation of epidermal growth factor-activated receptor activity|spleen development|cell motility|PMA-inducible membrane protein ectodomain proteolysis|PMA-inducible membrane protein ectodomain proteolysis|positive regulation of cellular component movement|response to high density lipoprotein particle|,metalloendopeptidase activity|Notch binding|interleukin-6 receptor binding|integrin binding|protein binding|peptidase activity|metallopeptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|SH3 domain binding|PDZ domain binding|metal ion binding|,10,-0.6,3.05,10,0.3,0.464,-0.4,1.73,-1.73,0.541,0,0,-1.8,1.1
ENSMUSG00000000817,FASL,"Fas ligand (TNF superfamily, member 6)",extracellular region|extracellular space|nucleus|lysosome|plasma membrane|caveola|external side of plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|inflammatory cell apoptotic process|immune response|positive regulation of cell proliferation|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of angiogenesis|cellular chloride ion homeostasis|positive regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of epidermal growth factor receptor signaling pathway|retinal cell programmed cell death|endosomal lumen acidification|T cell apoptotic process|necroptotic process|apoptotic signaling pathway|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|necroptotic signaling pathway|positive regulation of endothelial cell apoptotic process|",death receptor binding|cytokine activity|tumor necrosis factor receptor binding|,10,-0.8,2.02,9,-0.2,0.291,-0.5,1.69,-1.69,0.547,0,0,-1.9,0.6
ENSMUSG00000037815,CTNNA1,"catenin (cadherin associated protein), alpha 1",acrosomal vesicle|cytoplasm|cytoskeleton|plasma membrane|plasma membrane|cell-cell junction|adherens junction|cell-cell adherens junction|cell-cell adherens junction|zonula adherens|intercalated disc|actin cytoskeleton|membrane|catenin complex|lamellipodium|cell junction|,cell adhesion|establishment or maintenance of cell polarity|negative regulation of neuroblast proliferation|negative regulation of neuroblast proliferation|gap junction assembly|cellular protein localization|regulation of cell proliferation|negative regulation of apoptotic process|apical junction assembly|positive regulation of smoothened signaling pathway|protein heterooligomerization|cellular response to indole-3-methanol|epithelial cell-cell adhesion|negative regulation of cell motility|negative regulation of integrin-mediated signaling pathway|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,structural molecule activity|protein binding|beta-catenin binding|vinculin binding|poly(A) RNA binding|gamma-catenin binding|cadherin binding|actin filament binding|,10,-0.2,0.459,10,-0.4,1.37,-0.3,1.69,-1.69,0.547,0,0,-1.6,1.1
ENSMUSG00000030268,BCAT1,"branched chain aminotransferase 1, cytosolic",cytoplasm|mitochondrion|cytosol|,metabolic process|cellular amino acid biosynthetic process|branched-chain amino acid metabolic process|branched-chain amino acid biosynthetic process|branched-chain amino acid catabolic process|mitotic G1 DNA damage checkpoint|cellular response to UV|,catalytic activity|branched-chain-amino-acid transaminase activity|branched-chain-amino-acid transaminase activity|transaminase activity|transferase activity|identical protein binding|L-leucine transaminase activity|L-valine transaminase activity|L-isoleucine transaminase activity|,10,0.7,2.23,10,-0.2,0.262,0.6,1.68,1.68,0.548,0,0,-0.8,1.7
ENSMUSG00000083012,FAM220A,"family with sequence similarity 220, member A",cellular_component|nucleus|,biological_process|,molecular_function|,9,-0.4,3.13,9,0.5,3.5,-0.3,1.67,-1.67,0.549,0,0,-1.4,1.7
ENSMUSG00000034345,GTF2H5,"general transcription factor IIH, polypeptide 5",core TFIIH complex|nucleus|nucleolus|,"DNA repair|nucleotide-excision repair|nucleotide-excision repair|nucleotide-excision repair, preincision complex assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription elongation from RNA polymerase I promoter|transcription elongation from RNA polymerase I promoter|rRNA processing|cellular response to DNA damage stimulus|cellular response to gamma radiation|",rDNA binding|,10,0.2,0.35,10,0.4,1.73,0.3,1.67,1.67,0.549,0,0,-0.6,1.6
ENSMUSG00000027115,KIF18A,kinesin family member 18A,ruffle|nucleus|cytoplasm|kinetochore microtubule|cytoskeleton|kinesin complex|microtubule|caveola|microtubule cytoskeleton|cell projection|,ATP catabolic process|transport|microtubule-based movement|microtubule depolymerization|mitotic metaphase plate congression|metabolic process|protein transport|,nucleotide binding|microtubule motor activity|actin binding|ATP binding|microtubule binding|plus-end-directed microtubule motor activity|ubiquitin binding|microtubule plus-end binding|tubulin-dependent ATPase activity|,10,-0.5,0.885,10,-0.3,1.13,-0.3,1.67,-1.67,0.549,0,0,-1.7,0.9
ENSMUSG00000039474,WFS1,Wolfram syndrome 1 homolog (human),endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,kidney development|renal water homeostasis|visual perception|visual perception|sensory perception of sound|ER-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum unfolded protein response|endoplasmic reticulum unfolded protein response|positive regulation of protein ubiquitination|endoplasmic reticulum calcium ion homeostasis|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|glucose homeostasis|negative regulation of programmed cell death|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of neuron apoptotic process|positive regulation of proteolysis|positive regulation of growth|protein stabilization|neurological system process|positive regulation of protein metabolic process|regulation of cell cycle|positive regulation of calcium ion transport|calcium ion homeostasis|polyubiquitinated misfolded protein transport|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of type B pancreatic cell apoptotic process|negative regulation of type B pancreatic cell apoptotic process|,transporter activity|calmodulin binding|ubiquitin protein ligase binding|activating transcription factor binding|calcium-dependent protein binding|ATPase binding|ATPase binding|,10,0,0,10,-0.3,2.7,-0.2,1.66,-1.66,0.551,0,0,-1.6,0.9
ENSMUSG00000056220,PLA2G4A,"phospholipase A2, group IVA (cytosolic, calcium-dependent)",nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|cytoplasmic vesicle|zymogen granule|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,ovulation from ovarian follicle|lipid metabolic process|metabolic process|positive regulation of cell proliferation|phospholipid catabolic process|response to organic substance|lipid catabolic process|arachidonic acid metabolic process|positive regulation of vesicle fusion|positive regulation of prostaglandin biosynthetic process|regulation of cell proliferation|positive regulation of apoptotic process|surfactant homeostasis|icosanoid biosynthetic process|decidualization|arachidonic acid secretion|arachidonic acid secretion|positive regulation of inflammatory response|response to calcium ion|cellular response to antibiotic|,phospholipase activity|lysophospholipase activity|phospholipase A2 activity|phospholipase A2 activity|calcium ion binding|calcium-dependent phospholipid binding|hydrolase activity|metal ion binding|calcium-dependent phospholipase A2 activity|,10,-0.3,0.871,10,-0.2,0.965,-0.2,1.66,-1.66,0.551,0,0,-1.5,1.1
ENSMUSG00000032298,NEIL1,nei endonuclease VIII-like 1 (E. coli),nucleus|nucleus|chromosome|cytoplasm|cytoskeleton|,DNA repair|base-excision repair|nucleotide-excision repair|cellular response to DNA damage stimulus|response to oxidative stress|metabolic process|negative regulation of nuclease activity|,"purine-specific mismatch base pair DNA N-glycosylase activity|nucleic acid binding|DNA binding|damaged DNA binding|catalytic activity|DNA-(apurinic or apyrimidinic site) lyase activity|uracil DNA N-glycosylase activity|protein C-terminus binding|zinc ion binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hydrolase activity, hydrolyzing N-glycosyl compounds|lyase activity|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA-3-methylbase glycosylase activity|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0,0,10,-0.9,4.3,-0.8,1.65,-1.65,0.552,0,0,-2,0.3
ENSMUSG00000062866,PHACTR2,phosphatase and actin regulator 2,cellular_component|,biological_process|,molecular_function|actin binding|,9,-0.5,3.63,9,1.1,1.44,-0.4,1.64,-1.64,0.553,0,0,-1.6,1.8
ENSMUSG00000020802,UBE2O,ubiquitin-conjugating enzyme E2O,nucleus|cytoplasm|,"protein monoubiquitination|positive regulation of BMP signaling pathway|retrograde transport, endosome to Golgi|protein K63-linked ubiquitination|","nucleotide binding|ubiquitin-protein transferase activity|ATP binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.4,3.25,10,-1.4,1.11,-0.4,1.64,-1.64,0.553,0,0,-2.8,0.5
ENSMUSG00000026495,EFCAB2,EF-hand calcium binding domain 2,cellular_component|,biological_process|,calcium ion binding|,10,-0.2,0.782,10,0.6,3.47,0.5,1.64,1.64,0.553,0,0,-0.9,1.6
ENSMUSG00000024422,DHX16,DEAH (Asp-Glu-Ala-His) box polypeptide 16,nucleus|,biological_process|,nucleotide binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,1.2,3.27,10,0.2,0.303,1.2,1.64,1.64,0.553,0,0,-0.6,3
ENSMUSG00000041498,KIF14,kinesin family member 14,microtubule|membrane|,regulation of cell adhesion|regulation of cell migration|regulation of Rap protein signal transduction|negative regulation of integrin activation|substrate adhesion-dependent cell spreading|establishment of protein localization|,nucleotide binding|ATP binding|PDZ domain binding|,10,0.3,1.97,9,0,0,0.2,1.64,1.64,0.553,0,0,-1.2,1.5
ENSMUSG00000052062,PARD3B,par-3 family cell polarity regulator beta,cellular_component|tight junction|membrane|cell junction|,cell cycle|biological_process|cell division|,molecular_function|,10,0,0,10,0.4,2.63,0.4,1.64,1.64,0.553,0,0,-0.6,1.7
ENSMUSG00000051279,GDF6,growth differentiation factor 6,extracellular region|extracellular space|,"apoptotic process|multicellular organismal development|positive regulation of pathway-restricted SMAD protein phosphorylation|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|activin receptor signaling pathway|growth|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|pathway-restricted SMAD protein phosphorylation|",cytokine activity|growth factor activity|protein homodimerization activity|,10,-0.7,3.4,10,-0.1,0.245,-0.6,1.64,-1.64,0.553,0,0,-1.9,0.8
ENSMUSG00000032328,TMEM30A,transmembrane protein 30A,endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|cytoplasmic vesicle|,transport|drug transmembrane transport|lipid transport|positive regulation of neuron projection development|neuron projection development|protein localization to endosome|phospholipid translocation|phospholipid translocation|positive regulation of protein exit from endoplasmic reticulum|,protein binding|,10,0.8,1.55,10,0.5,0.699,0.6,1.63,1.63,0.555,0,0,-0.5,1.9
ENSMUSG00000005370,MSH6,mutS homolog 6 (E. coli),nuclear chromatin|intracellular|nucleus|chromosome|cytoplasm|Golgi apparatus|plasma membrane|MutSalpha complex|MutSalpha complex|intracellular membrane-bounded organelle|,meiotic mismatch repair|ATP catabolic process|ATP catabolic process|DNA repair|mismatch repair|mismatch repair|mismatch repair|cellular response to DNA damage stimulus|reciprocal meiotic recombination|determination of adult lifespan|intrinsic apoptotic signaling pathway in response to DNA damage|response to UV|somatic hypermutation of immunoglobulin genes|somatic recombination of immunoglobulin gene segments|maintenance of DNA repeat elements|isotype switching|negative regulation of DNA recombination|negative regulation of DNA recombination|positive regulation of helicase activity|intrinsic apoptotic signaling pathway|,nucleotide binding|magnesium ion binding|four-way junction DNA binding|four-way junction DNA binding|DNA binding|DNA binding|chromatin binding|damaged DNA binding|damaged DNA binding|double-stranded DNA binding|ATP binding|DNA-dependent ATPase activity|ATPase activity|mismatched DNA binding|mismatched DNA binding|guanine/thymine mispair binding|guanine/thymine mispair binding|guanine/thymine mispair binding|single base insertion or deletion binding|single guanine insertion binding|single thymine insertion binding|oxidized purine DNA binding|MutLalpha complex binding|methylated histone binding|ADP binding|,10,0.4,1.71,10,0.2,0.366,0.3,1.63,1.63,0.555,0,0,-1.3,1.5
ENSMUSG00000061374,FIZ1,Flt3 interacting zinc finger protein 1,nucleus|cytoplasm|,"positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|protein binding|receptor tyrosine kinase binding|metal ion binding|,10,0.4,1.76,10,0.2,0.347,0.4,1.62,1.62,0.556,0,0,-0.6,1.7
ENSMUSG00000001552,JUP,junction plakoglobin,nucleus|cytoplasm|cytosol|cytoskeleton|intermediate filament|plasma membrane|cell-cell junction|cell-cell junction|cell-cell adherens junction|cell-cell adherens junction|zonula adherens|fascia adherens|fascia adherens|cytoplasmic side of plasma membrane|cytoplasmic side of plasma membrane|intercalated disc|actin cytoskeleton|actin cytoskeleton|membrane|basolateral plasma membrane|apicolateral plasma membrane|lateral plasma membrane|catenin complex|catenin complex|Z disc|cell junction|desmosome|desmosome|desmosome|beta-catenin destruction complex|protein-DNA complex|extracellular vesicular exosome|gamma-catenin-TCF7L2 complex|,cell morphogenesis|desmosome assembly|desmosome assembly|negative regulation of heart induction by canonical Wnt signaling pathway|atrioventricular valve morphogenesis|negative regulation of Wnt signaling pathway involved in heart development|cytoskeletal anchoring at plasma membrane|cell adhesion|gastrulation|ectoderm development|nervous system development|morphogenesis of embryonic epithelium|single organismal cell-cell adhesion|single organismal cell-cell adhesion|cell migration|regulation of cell proliferation|positive regulation of protein import into nucleus|skin development|positive regulation of transcription from RNA polymerase II promoter|oocyte development|detection of mechanical stimulus|positive regulation of sequence-specific DNA binding transcription factor activity|protein heterooligomerization|cellular response to indole-3-methanol|ventricular cardiac muscle cell action potential|bundle of His cell to Purkinje myocyte communication|regulation of heart rate by cardiac conduction|establishment of protein localization to plasma membrane|,transcription coactivator activity|transcription coactivator activity|structural molecule activity|structural molecule activity|protein binding|protein kinase binding|protein kinase binding|protein phosphatase binding|alpha-catenin binding|alpha-catenin binding|cadherin binding|cadherin binding|,10,0.3,1.12,10,0.2,0.622,0.3,1.61,1.61,0.557,0,0,-0.7,1.6
ENSMUSG00000031921,TERF2,telomeric repeat binding factor 2,"chromosome, telomeric region|nuclear telomere cap complex|nuclear telomere cap complex|nuclear chromosome, telomeric region|male germ cell nucleus|nucleus|chromosome|cytoplasm|Golgi apparatus|Mre11 complex|","telomere maintenance|telomere maintenance|in utero embryonic development|cell cycle|telomere maintenance via telomere shortening|telomere capping|telomeric loop formation|protection from non-homologous end joining at telomere|protection from non-homologous end joining at telomere|protection from non-homologous end joining at telomere|negative regulation of telomere maintenance|positive regulation of telomere maintenance|positive regulation of telomere maintenance|protein localization to chromosome, telomeric region|",DNA binding|chromatin binding|double-stranded telomeric DNA binding|protein binding|protein C-terminus binding|telomeric DNA binding|protein homodimerization activity|protein homodimerization activity|,4,-0.2,0.556,5,-0.7,1.91,-0.4,1.61,-1.61,0.557,0,0,-2,0.9
ENSMUSG00000046070,IGFALS,"insulin-like growth factor binding protein, acid labile subunit",extracellular region|nucleus|insulin-like growth factor ternary complex|intracellular membrane-bounded organelle|extracellular vesicular exosome|,cell adhesion|,protein binding|insulin-like growth factor binding|protein C-terminus binding|,10,0,0,10,0.4,3,0.3,1.61,1.61,0.557,0,0,-0.3,2
ENSMUSG00000017724,ETV4,ets variant 4,intracellular|nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|motor neuron axon guidance|positive regulation of gene expression|negative regulation of mammary gland epithelial cell proliferation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|stem cell differentiation|branching involved in mammary gland duct morphogenesis|regulation of branching involved in mammary gland duct morphogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.1,0.488,10,0.4,1.89,0.3,1.61,1.61,0.557,0,0,-0.3,1.9
ENSMUSG00000031906,SMPD3,"sphingomyelin phosphodiesterase 3, neutral",Golgi cis cisterna|cell|Golgi apparatus|plasma membrane|membrane|,hematopoietic progenitor cell differentiation|lipid metabolic process|sphingolipid metabolic process|sphingomyelin metabolic process|cell cycle|signal transduction|multicellular organismal development|peptide hormone secretion|,sphingomyelin phosphodiesterase activity|sphingomyelin phosphodiesterase activity|hydrolase activity|metal ion binding|,10,-0.2,0.727,10,-0.3,1.02,-0.2,1.6,-1.6,0.559,0,0,-1.5,1.1
ENSMUSG00000068457,UTY,"ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome",nucleus|protein complex|,in utero embryonic development|heart morphogenesis|heart development|regulation of gene expression|chromatin modification|regulation of chromatin silencing|establishment of protein localization|embryonic organ development|oxidation-reduction process|canonical Wnt signaling pathway|histone H3-K36 demethylation|cardiac muscle cell contraction|,"sulfonate dioxygenase activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding|protein binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|histone demethylase activity (H3-K36 specific)|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,1.5,1.15,10,0.5,2.28,0.5,1.59,1.59,0.56,0,0,-0.4,2.9
ENSMUSG00000029994,ANXA4,annexin A4,nucleus|cytoplasm|plasma membrane|cell surface|vesicle membrane|apical plasma membrane|nuclear membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,kidney development|regulation of transcription from RNA polymerase II promoter|negative regulation of NF-kappaB transcription factor activity|negative regulation of interleukin-8 secretion|,calcium ion binding|calcium-dependent phospholipid binding|identical protein binding|calcium-dependent protein binding|NF-kappaB binding|,10,-0.4,1.59,10,-0.2,0.259,-0.4,1.59,-1.59,0.56,0,0,-1.8,0.9
ENSMUSG00000009073,NF2,neurofibromatosis 2,ruffle|nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|early endosome|cytoskeleton|plasma membrane|adherens junction|membrane|membrane|extrinsic component of membrane|lamellipodium|filopodium|cortical actin cytoskeleton|cleavage furrow|cell projection|protein complex|membrane raft|apical part of cell|synapse|perinuclear region of cytoplasm|,mesoderm formation|negative regulation of protein kinase activity|negative regulation of protein kinase activity|ectoderm development|brain development|negative regulation of DNA replication|negative regulation of cell proliferation|negative regulation of cell proliferation|Schwann cell proliferation|hippocampus development|negative regulation of cell-cell adhesion|actin cytoskeleton organization|negative regulation of cell growth|regulation of protein stability|regulation of hippo signaling|regulation of cell proliferation|odontogenesis of dentin-containing tooth|negative regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of MAPK cascade|cell-cell junction organization|positive regulation of cell differentiation|negative regulation of JAK-STAT cascade|positive regulation of stress fiber assembly|lens fiber cell differentiation|regulation of protein localization to nucleus|regulation of neural precursor cell proliferation|,actin binding|integrin binding|protein binding|beta-catenin binding|cytoskeletal protein binding|protein domain specific binding|,10,-0.3,1.03,10,-0.3,0.695,-0.3,1.59,-1.59,0.56,0,0,-1.3,1.7
ENSMUSG00000053279,ALDH1A1,"aldehyde dehydrogenase family 1, subfamily A1",nucleus|cytoplasm|extracellular vesicular exosome|,optic cup morphogenesis involved in camera-type eye development|retinoic acid biosynthetic process|response to oxidative stress|metabolic process|response to drug|retinol metabolic process|retinoic acid metabolic process|retinoic acid metabolic process|retinoic acid metabolic process|9-cis-retinoic acid biosynthetic process|9-cis-retinoic acid metabolic process|positive regulation of apoptotic process|response to ethanol|embryonic eye morphogenesis|protein homotetramerization|oxidation-reduction process|,"retinal dehydrogenase activity|3-chloroallyl aldehyde dehydrogenase activity|aldehyde dehydrogenase (NAD) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|benzaldehyde dehydrogenase (NAD+) activity|identical protein binding|",10,-1.1,2.54,10,0,0,-1.1,1.57,-1.57,0.563,0,0,-2,0.5
ENSMUSG00000029373,PF4,platelet factor 4,extracellular region|extracellular space|platelet alpha granule|vesicle|protein complex|,protein complex assembly|chemotaxis|immune response|positive regulation of gene expression|positive regulation of macrophage derived foam cell differentiation|negative regulation of angiogenesis|cytokine-mediated signaling pathway|platelet activation|leukocyte chemotaxis|positive regulation of cAMP metabolic process|positive regulation of tumor necrosis factor production|regulation of cell proliferation|positive regulation of cAMP-mediated signaling|negative regulation of MHC class II biosynthetic process|positive regulation of macrophage differentiation|negative regulation of megakaryocyte differentiation|negative regulation of cytolysis|positive regulation of transcription from RNA polymerase II promoter|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,cytokine activity|chemokine activity|heparin binding|CXCR3 chemokine receptor binding|,10,0.4,0.905,10,0.4,0.796,0.4,1.57,1.57,0.563,0,0,-0.5,1.8
ENSMUSG00000020453,PATZ1,POZ (BTB) and AT hook containing zinc finger 1,nucleus|nucleus|,"regulation of transcription, DNA-templated|spermatogenesis|male gonad development|regulation of gene expression|T cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",DNA binding|chromatin binding|protein binding|metal ion binding|,10,0.2,1.37,10,0.2,0.323,0.2,1.57,1.57,0.563,0,0,-0.2,2
ENSMUSG00000026039,SGOL2,shugoshin-like 2 (S. pombe),"chromosome, centromeric region|chromosome, centromeric region|kinetochore|condensed chromosome, centromeric region|condensed nuclear chromosome, centromeric region|nucleus|chromosome|mitotic cohesin complex|","cell cycle|chromosome segregation|meiotic nuclear division|male meiosis|female meiotic division|protein localization|cell division|meiotic sister chromatid cohesion, centromeric|positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric|",protein binding|,10,-0.2,0.595,10,-0.3,1.24,-0.2,1.56,-1.56,0.565,0,0,-1.8,0.6
ENSMUSG00000054863,FAM19A5,"family with sequence similarity 19, member A5",cellular_component|extracellular region|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.41,10,0.2,0.334,0.3,1.56,1.56,0.565,0,0,-1.1,1.8
ENSMUSG00000031289,IL13RA2,"interleukin 13 receptor, alpha 2",extracellular region|membrane|integral component of membrane|,None,cytokine receptor activity|,10,-0.5,2.69,10,0,0,-0.2,1.55,-1.55,0.567,0,0,-1.6,1
ENSMUSG00000021250,FOS,FBJ osteosarcoma oncogene,nucleus|nucleus|nucleus|transcription factor complex|cytoplasm|endoplasmic reticulum|membrane|neuron projection|,"regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transforming growth factor beta receptor signaling pathway|nervous system development|cellular response to extracellular stimulus|cellular response to reactive oxygen species|skeletal muscle cell differentiation|response to drug|positive regulation of osteoclast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|SMAD protein signal transduction|cellular response to calcium ion|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|R-SMAD binding|,10,0.7,2.58,10,0.1,0.265,0.3,1.55,1.55,0.567,0,0,-0.6,1.8
ENSMUSG00000005897,NR2C1,"nuclear receptor subfamily 2, group C, member 1",nucleus|PML body|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|steroid hormone mediated signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of retinoic acid receptor signaling pathway|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|protein binding|zinc ion binding|protein homodimerization activity|histone deacetylase binding|sequence-specific DNA binding|metal ion binding|,10,-0.5,1.75,10,0.2,0.707,-0.3,1.55,-1.55,0.567,0,0,-1.5,1.1
ENSMUSG00000026360,RGS2,regulator of G-protein signaling 2,nucleus|cytoplasm|cytosol|plasma membrane|plasma membrane|cytoplasmic side of plasma membrane|cytoplasmic side of plasma membrane|membrane|neuron projection|,regulation of translation|cell cycle|G-protein coupled receptor signaling pathway|negative regulation of signal transduction|negative regulation of phospholipase activity|negative regulation of cardiac muscle hypertrophy|positive regulation of microtubule polymerization|termination of G-protein coupled receptor signaling pathway|negative regulation of MAP kinase activity|positive regulation of GTPase activity|positive regulation of GTPase activity|negative regulation of cAMP-mediated signaling|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein coupled receptor protein signaling pathway|brown fat cell differentiation|relaxation of cardiac muscle|relaxation of vascular smooth muscle|positive regulation of cardiac muscle contraction|regulation of adrenergic receptor signaling pathway|,GTPase activator activity|GTPase activator activity|GTPase activator activity|protein binding|beta-tubulin binding|,10,-0.1,0.152,10,1.1,3.45,0.4,1.55,1.55,0.567,0,0,-0.7,2
ENSMUSG00000022797,TFRC,transferrin receptor,extracellular region|extracellular space|mitochondrion|endosome|endosome|plasma membrane|plasma membrane|coated pit|coated pit|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|recycling endosome|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|extracellular vesicular exosome|blood microparticle|,cellular iron ion homeostasis|endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|osteoclast differentiation|iron ion transmembrane transport|positive regulation of bone resorption|iron ion import|,double-stranded RNA binding|transferrin receptor activity|transferrin receptor activity|iron ion transmembrane transporter activity|protein binding|Hsp70 protein binding|identical protein binding|poly(A) RNA binding|chaperone binding|,10,0.7,1.94,10,-0.4,2.51,-0.3,1.55,-1.55,0.567,0,0,-1.3,1.7
ENSMUSG00000027399,IL1A,interleukin 1 alpha,extracellular region|extracellular space|extracellular space|cytosol|plasma membrane|cell surface|,fever generation|inflammatory response|immune response|negative regulation of cell proliferation|positive regulation vascular endothelial growth factor production|positive regulation of steroid biosynthetic process|cytokine-mediated signaling pathway|keratinization|positive regulation of prostaglandin secretion|positive regulation of interleukin-6 production|positive regulation of stress-activated MAPK cascade|cellular response to heat|ectopic germ cell programmed cell death|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of interleukin-2 biosynthetic process|positive regulation of angiogenesis|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|response to copper ion|positive regulation of cytokine secretion|positive regulation of cell division|regulation of sensory perception of pain|positive regulation of ERK1 and ERK2 cascade|extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of neutrophil migration|,cytokine activity|interleukin-1 receptor binding|copper ion binding|,10,-0.4,2.77,10,0,0,-0.2,1.53,-1.53,0.569,0,0,-1.5,1.2
ENSMUSG00000028519,DAB1,disabled 1,intracellular|intracellular|cytosol|brush border|postsynaptic density|membrane|neuron projection|neuronal cell body|apical part of cell|perinuclear region of cytoplasm|,neuron migration|neuron migration|neuron migration|negative regulation of cell adhesion|small GTPase mediated signal transduction|multicellular organismal development|nervous system development|central nervous system development|adult walking behavior|dendrite development|dendrite development|cerebellum structural organization|cerebral cortex cell migration|cerebral cortex radially oriented cell migration|cerebral cortex radially oriented cell migration|cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration|radial glia guided migration of Purkinje cell|cell differentiation|intracellular signal transduction|positive regulation of neuron differentiation|positive regulation of protein kinase activity|negative regulation of JAK-STAT cascade|negative regulation of astrocyte differentiation|negative regulation of axonogenesis|negative regulation of axonogenesis|Golgi localization|lateral motor column neuron migration|,protein binding|phospholipid binding|SH2 domain binding|phosphatidylinositol 3-kinase binding|,10,0.2,0.498,10,0.4,1.32,0.3,1.53,1.53,0.569,0,0,-0.7,1.7
ENSMUSG00000025911,ADHFE1,"alcohol dehydrogenase, iron containing, 1",mitochondrion|,molecular hydrogen transport|oxidation-reduction process|,oxidoreductase activity|metal ion binding|hydroxyacid-oxoacid transhydrogenase activity|,10,0.2,0.987,10,0.2,0.662,0.2,1.52,1.52,0.571,0,0,-1.3,1.4
ENSMUSG00000021234,FAM161B,"family with sequence similarity 161, member B",cellular_component|,biological_process|,molecular_function|,10,0.6,2.28,10,0.1,0.135,0.2,1.52,1.52,0.571,0,0,-0.4,1.9
ENSMUSG00000002307,DAXX,Fas death domain-associated protein,heterochromatin|nucleus|nucleus|cytoplasm|cytosol|cell cortex|PML body|PML body|neuron projection|cell body|SWI/SNF superfamily-type complex|,"mitotic cytokinesis|positive regulation of protein phosphorylation|nucleosome assembly|nucleosome assembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|chromatin modification|androgen receptor signaling pathway|regulation of protein ubiquitination|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|apoptotic signaling pathway|positive regulation of neuron death|regulation of RNA biosynthetic process|positive regulation of apoptotic signaling pathway|positive regulation of apoptotic signaling pathway|",p53 binding|transcription coactivator activity|transcription corepressor activity|transcription corepressor activity|protein binding|transcription factor binding|enzyme binding|protein kinase binding|protein kinase activator activity|ubiquitin protein ligase binding|histone binding|histone binding|protein homodimerization activity|protein N-terminus binding|androgen receptor binding|,9,1.5,4.52,10,-0.5,3.42,1.5,1.51,1.51,0.572,0,0,-1,3
ENSMUSG00000026239,PDE6D,"phosphodiesterase 6D, cGMP-specific, rod, delta",cytoplasm|cytosol|membrane|cytoplasmic vesicle|,visual perception|phototransduction|regulation of GTP catabolic process|negative regulation of catalytic activity|response to stimulus|,"3',5'-cyclic-nucleotide phosphodiesterase activity|GTPase inhibitor activity|protein binding|Rab GTPase binding|3',5'-cyclic-GMP phosphodiesterase activity|",10,0.4,1.06,10,0.2,1.06,0.3,1.51,1.51,0.572,0,0,-0.9,1.6
ENSMUSG00000026082,REV1,REV1 homolog (S. cerevisiae),nucleus|,DNA replication|DNA repair|cellular response to DNA damage stimulus|response to UV|error-prone translesion synthesis|,"magnesium ion binding|DNA binding|damaged DNA binding|telomerase activity|RNA helicase activity|DNA-directed DNA polymerase activity|DNA primase activity|sulfate adenylyltransferase activity|RNA guanylyltransferase activity|tRNA guanylyltransferase activity|mannose-phosphate guanylyltransferase activity|transferase activity|nucleotidyltransferase activity|deoxycytidyl transferase activity|DNA/RNA helicase activity|CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity|phospholactate guanylyltransferase activity|ATP:coenzyme F420 adenylyltransferase activity|metal ion binding|UDP-N-acetylgalactosamine diphosphorylase activity|",10,0.1,0.38,10,0.6,1.64,0.3,1.5,1.5,0.574,0,0,-0.4,1.8
ENSMUSG00000067924,CXX1B,CAAX box 1B,cellular_component|,biological_process|,molecular_function|,10,-0.4,3.45,10,0,0,-0.3,1.5,-1.5,0.574,0,0,-1.7,0.7
ENSMUSG00000036061,SMUG1,single-strand selective monofunctional uracil DNA glycosylase,nucleus|nucleolus|nucleolus|,"DNA catabolic process, endonucleolytic|DNA repair|DNA repair|base-excision repair|base-excision repair|cellular response to DNA damage stimulus|metabolic process|","purine-specific mismatch base pair DNA N-glycosylase activity|oxidized base lesion DNA N-glycosylase activity|oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity|DNA binding|single-stranded DNA binding|uracil DNA N-glycosylase activity|uracil DNA N-glycosylase activity|uracil DNA N-glycosylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|single-strand selective uracil DNA N-glycosylase activity|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA N-glycosylase activity|DNA-3-methylbase glycosylase activity|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,-0.2,0.99,10,-0.2,0.638,-0.2,1.5,-1.5,0.574,0,0,-1.7,0.7
ENSMUSG00000027358,BMP2,bone morphogenetic protein 2,extracellular region|extracellular space|extracellular space|cytoplasm|cell surface|membrane-bounded vesicle|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|activation of MAPK activity|ossification|osteoblast differentiation|osteoblast differentiation|osteoblast differentiation|branching involved in ureteric bud morphogenesis|response to hypoxia|in utero embryonic development|epithelial to mesenchymal transition|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|chondrocyte differentiation|BMP signaling pathway involved in heart induction|atrioventricular valve morphogenesis|endocardial cushion morphogenesis|negative regulation of Wnt signaling pathway involved in heart development|proteoglycan metabolic process|regulation of transcription, DNA-templated|protein phosphorylation|transforming growth factor beta receptor signaling pathway|Notch signaling pathway|multicellular organismal development|heart development|negative regulation of cell proliferation|negative regulation of cell proliferation|embryo development|organ morphogenesis|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of steroid biosynthetic process|positive regulation of phosphatase activity|telencephalon development|telencephalon regionalization|cell differentiation|positive regulation of Wnt signaling pathway|bone mineralization|bone mineralization|positive regulation of cell migration|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|protein destabilization|protein destabilization|negative regulation of aldosterone biosynthetic process|positive regulation of osteoblast proliferation|cardiocyte differentiation|embryonic heart tube anterior/posterior pattern specification|bone mineralization involved in bone maturation|growth|odontogenesis of dentin-containing tooth|positive regulation of odontogenesis|regulation of odontogenesis of dentin-containing tooth|positive regulation of apoptotic process|positive regulation of MAPK cascade|negative regulation of insulin-like growth factor receptor signaling pathway|cell fate commitment|positive regulation of cell differentiation|positive regulation of fat cell differentiation|positive regulation of neuron differentiation|positive regulation of osteoblast differentiation|positive regulation of osteoblast differentiation|positive regulation of osteoblast differentiation|positive regulation of ossification|positive regulation of ossification|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of astrocyte differentiation|positive regulation of astrocyte differentiation|mesenchymal cell differentiation|inner ear development|positive regulation of neurogenesis|negative regulation of calcium-independent cell-cell adhesion|cartilage development|cardiac muscle cell differentiation|cardiac muscle tissue morphogenesis|oxidation-reduction process|pericardium development|corticotropin hormone secreting cell differentiation|thyroid-stimulating hormone-secreting cell differentiation|cardiac epithelial to mesenchymal transition|pathway-restricted SMAD protein phosphorylation|SMAD protein signal transduction|mesenchyme development|positive regulation of Wnt signaling pathway by BMP signaling pathway|positive regulation of cartilage development|positive regulation of cartilage development|positive regulation of ERK1 and ERK2 cascade|cellular response to growth factor stimulus|cellular response to organic cyclic compound|cellular response to BMP stimulus|mesenchymal cell proliferation involved in ureteric bud development|positive regulation of p38MAPK cascade|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|negative regulation of cortisol biosynthetic process|negative regulation of cardiac muscle cell differentiation|",retinol dehydrogenase activity|receptor binding|cytokine activity|protein binding|growth factor activity|phosphatase activator activity|protein domain specific binding|protein homodimerization activity|SMAD binding|protein heterodimerization activity|BMP receptor binding|,10,-0.5,2.57,10,0.2,0.134,-0.3,1.5,-1.5,0.574,0,0,-1.9,0.5
ENSMUSG00000038155,GSTP2,"glutathione S-transferase, pi 2",extracellular space|intracellular|nucleus|cytoplasm|mitochondrion|cytosol|plasma membrane|extracellular vesicular exosome|TRAF2-GSTP1 complex|,glutathione metabolic process|metabolic process|,glutathione transferase activity|glutathione transferase activity|drug binding|transferase activity|S-nitrosoglutathione binding|dinitrosyl-iron complex binding|glutathione binding|,10,0,0,10,-0.4,3.06,-0.3,1.49,-1.49,0.575,0,0,-1.8,0.6
ENSMUSG00000030772,DKK3,dickkopf homolog 3 (Xenopus laevis),extracellular region|extracellular space|,"multicellular organismal development|Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of aldosterone biosynthetic process|negative regulation of transcription, DNA-templated|negative regulation of canonical Wnt signaling pathway|negative regulation of cortisol biosynthetic process|",None,10,1.1,3.6,10,0,0,0.2,1.49,1.49,0.575,0,0,-0.2,2
ENSMUSG00000050229,PIGM,"phosphatidylinositol glycan anchor biosynthesis, class M",cellular_component|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|mannosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.3,0.993,10,-0.2,0.657,-0.2,1.48,-1.48,0.577,0,0,-1.6,0.9
ENSMUSG00000044548,DACT1,"dapper homolog 1, antagonist of beta-catenin (xenopus)",nucleus|cytoplasm|cell junction|beta-catenin destruction complex|beta-catenin destruction complex|synapse|,"negative regulation of transcription from RNA polymerase II promoter|gastrulation with mouth forming second|multicellular organismal development|nervous system development|Wnt signaling pathway|positive regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|regulation of protein stability|regulation of catenin import into nucleus|positive regulation of catenin import into nucleus|positive regulation of fat cell differentiation|positive regulation of protein catabolic process|negative regulation of JNK cascade|negative regulation of JNK cascade|embryonic morphogenesis|embryonic hindgut morphogenesis|dendrite morphogenesis|dendrite morphogenesis|synapse organization|negative regulation of canonical Wnt signaling pathway|regulation of Wnt signaling pathway, planar cell polarity pathway|regulation of Wnt signaling pathway, planar cell polarity pathway|negative regulation of G1/S transition of mitotic cell cycle|",protein kinase C binding|protein binding|beta-catenin binding|protein kinase A binding|protein kinase A binding|delta-catenin binding|,10,0.1,0.149,10,-0.4,1.6,-0.3,1.48,-1.48,0.577,0,0,-1.6,1.1
ENSMUSG00000062075,LMNB2,lamin B2,nucleus|nuclear envelope|nuclear inner membrane|lamin filament|intermediate filament|membrane|,None,structural molecule activity|,10,-0.9,2.39,10,0.5,2.59,0.5,1.48,1.48,0.577,0,0,-1.9,1.1
ENSMUSG00000037573,TOB1,transducer of ErbB-2.1,nucleus|cytoplasm|CCR4-NOT complex|,"SMAD protein import into nucleus|negative regulation of cell proliferation|negative regulation of translation|negative regulation of BMP signaling pathway|negative regulation of osteoblast differentiation|negative regulation of nuclear-transcribed mRNA poly(A) tail shortening|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|regulation of RNA biosynthetic process|",transcription corepressor activity|protein binding|receptor tyrosine kinase binding|SMAD binding|,10,2,3.61,10,0.3,0.447,1.7,1.48,1.48,0.577,0,0,-0.5,3
ENSMUSG00000060679,MRPS9,mitochondrial ribosomal protein S9,nucleolus|mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,-0.4,3.68,10,0.1,0.182,-0.3,1.47,-1.47,0.578,0,0,-1.4,1.4
ENSMUSG00000019699,AKT3,thymoma viral proto-oncogene 3,nucleus|cytoplasm|Golgi apparatus|plasma membrane|membrane|,mitochondrial genome maintenance|protein phosphorylation|signal transduction|positive regulation of sodium ion transport|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|cellular response to insulin stimulus|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.6,2.47,10,-0.3,0.378,0.3,1.47,1.47,0.578,0,0,-0.8,1.7
ENSMUSG00000031478,NEK3,NIMA (never in mitosis gene a)-related expressed kinase 3,cytoplasm|cell projection|,protein phosphorylation|cell cycle|mitotic nuclear division|phosphorylation|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.1,0.0352,10,-0.3,2.11,-0.3,1.46,-1.46,0.58,0,0,-1.7,0.8
ENSMUSG00000033538,CASP4,"caspase 4, apoptosis-related cysteine peptidase",cytoplasm|mitochondrion|endoplasmic reticulum|membrane|neuron projection|neuronal cell body|protein complex|IPAF inflammasome complex|NLRP3 inflammasome complex|AIM2 inflammasome complex|,proteolysis|proteolysis|apoptotic process|actin filament organization|ectopic germ cell programmed cell death|ectopic germ cell programmed cell death|regulation of apoptotic process|positive regulation of interleukin-1 beta secretion|regulation of inflammatory response|pyroptosis|execution phase of apoptosis|,cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|scaffold protein binding|,10,0.6,3.5,10,-0.1,0.0343,0.4,1.45,1.45,0.581,0,0,-0.7,1.9
ENSMUSG00000024066,XDH,xanthine dehydrogenase,extracellular region|extracellular space|cytoplasm|peroxisome|cytosol|,negative regulation of protein phosphorylation|negative regulation of endothelial cell proliferation|activation of cysteine-type endopeptidase activity involved in apoptotic process|lactation|xanthine catabolic process|response to aluminum ion|negative regulation of gene expression|regulation of epithelial cell differentiation|bone resorption|negative regulation of endothelial cell differentiation|negative regulation of protein kinase B signaling|oxidation-reduction process|oxidation-reduction process|positive regulation of p38MAPK cascade|negative regulation of vascular endothelial growth factor signaling pathway|positive regulation of reactive oxygen species metabolic process|negative regulation of vasculogenesis|,"catalytic activity|xanthine dehydrogenase activity|xanthine dehydrogenase activity|xanthine oxidase activity|iron ion binding|protein binding|UDP-N-acetylmuramate dehydrogenase activity|electron carrier activity|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|molybdenum ion binding|protein homodimerization activity|molybdopterin cofactor binding|metal ion binding|flavin adenine dinucleotide binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,-0.3,0.255,10,-0.2,1.35,-0.2,1.45,-1.45,0.581,0,0,-1.6,1
ENSMUSG00000027840,WNT2B,"wingless-type MMTV integration site family, member 2B",extracellular region|proteinaceous extracellular matrix|extracellular space|,signal transduction|cell-cell signaling|multicellular organismal development|cellular response to starvation|organ morphogenesis|Wnt signaling pathway|neuron differentiation|canonical Wnt signaling pathway|lung induction|mesenchymal-epithelial cell signaling|hematopoietic stem cell proliferation|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of canonical Wnt signaling pathway|,receptor binding|frizzled binding|protein binding|,10,-0.3,2.2,10,0.4,0.418,-0.2,1.45,-1.45,0.581,0,0,-1.4,1.3
ENSMUSG00000020230,PRMT2,protein arginine N-methyltransferase 2,nucleus|cytoplasm|cytosol|cytosol|Rb-E2F complex|,"response to hypoxia|protein methylation|histone methylation|histone methylation|peptidyl-arginine methylation, to asymmetrical-dimethyl arginine|negative regulation of NF-kappaB transcription factor activity|methylation|leptin-mediated signaling pathway|histone arginine methylation|peptidyl-arginine N-methylation|regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|developmental cell growth|regulation of androgen receptor signaling pathway|negative regulation of G1/S transition of mitotic cell cycle|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|transcription coactivator activity|transcription coactivator activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|beta-catenin binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|histone-arginine N-methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|estrogen receptor binding|methylarsonite methyltransferase activity|progesterone receptor binding|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|protein-arginine omega-N asymmetric methyltransferase activity|histone methyltransferase activity|protein homodimerization activity|retinoic acid receptor binding|peroxisome proliferator activated receptor binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|thyroid hormone receptor binding|androgen receptor binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.4,1.64,10,0.3,0.0773,0.4,1.45,1.45,0.581,0,0,-0.5,1.8
ENSMUSG00000070448,VMN2R89,"vomeronasal 2, receptor 89",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.49,10,0.2,0.371,-0.3,1.45,-1.45,0.581,0,0,-1.8,0.8
ENSMUSG00000079445,B3GNT7,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7",cellular_component|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,0.6,2.49,0.3,1.44,1.44,0.583,0,0,-1.1,1.8
ENSMUSG00000009621,VAV2,vav 2 oncogene,intracellular|cytoplasm|plasma membrane|,angiogenesis|small GTPase mediated signal transduction|regulation of gene expression|cell migration|cell projection assembly|lamellipodium assembly|regulation of blood coagulation|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of GTPase activity|positive regulation of GTPase activity|positive regulation of phosphatidylinositol 3-kinase activity|,guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|epidermal growth factor receptor binding|protein binding|metal ion binding|,10,1.2,4.54,10,-0.1,0.15,1.2,1.44,1.44,0.583,0,0,-0.3,2.9
ENSMUSG00000054256,MSI1,musashi RNA-binding protein 1,nucleus|cytoplasm|polysome|,response to hormone|,nucleotide binding|nucleic acid binding|RNA binding|single-stranded RNA binding|poly(U) RNA binding|poly(A) RNA binding|,10,0.1,0.259,10,0.4,1.8,0.3,1.44,1.44,0.583,0,0,-0.4,2
ENSMUSG00000037470,UGGT1,UDP-glucose glycoprotein glucosyltransferase 1,endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum-Golgi intermediate compartment|extracellular vesicular exosome|,protein glycosylation|UDP-glucosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|protein binding|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|unfolded protein binding|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.1,0.0183,10,0.3,1.78,0.2,1.43,1.43,0.585,0,0,-1.9,1.3
ENSMUSG00000021694,ERCC8,"excision repaiross-complementing rodent repair deficiency, complementation group 8",nucleotide-excision repair complex|nucleus|nuclear matrix|Cul4A-RING E3 ubiquitin ligase complex|protein complex|,protein polyubiquitination|DNA repair|transcription-coupled nucleotide-excision repair|nucleotide-excision repair|cellular response to DNA damage stimulus|response to oxidative stress|response to UV|response to UV|response to X-ray|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of DNA repair|protein autoubiquitination|,ubiquitin-protein transferase activity|protein complex binding|,10,0,0,10,1,3.42,0.4,1.43,1.43,0.585,0,0,-0.9,2
ENSMUSG00000026270,CAPN10,calpain 10,intracellular|cell|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial intermembrane space|mitochondrial matrix|cytosol|cytoskeleton|plasma membrane|cell cortex|intracellular membrane-bounded organelle|,mitochondrion degradation|proteolysis|proteolysis|mitochondrion organization|aging|actin cytoskeleton reorganization|actin cytoskeleton reorganization|response to nutrient levels|positive regulation of insulin secretion|positive regulation of intracellular transport|cellular response to insulin stimulus|cellular response to insulin stimulus|positive regulation of apoptotic process|positive regulation of glucose import|positive regulation of glucose import|type B pancreatic cell apoptotic process|type B pancreatic cell apoptotic process|positive regulation of type B pancreatic cell apoptotic process|,SNARE binding|calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|cytoskeletal protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.7,1.94,10,0,0,0.6,1.43,1.43,0.585,0,0,-0.5,1.9
ENSMUSG00000027198,EXT2,exostoses (multiple) 2,Golgi membrane|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|extracellular vesicular exosome|,"ossification|mesoderm formation|glycosaminoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process|cell differentiation|cellular polysaccharide biosynthetic process|","acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|glucuronosyltransferase activity|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|heparan sulfate N-acetylglucosaminyltransferase activity|protein homodimerization activity|protein heterodimerization activity|glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity|",10,0.2,0.8,10,0.5,1.6,0.3,1.42,1.42,0.586,0,0,-0.9,1.6
ENSMUSG00000030551,NR2F2,"nuclear receptor subfamily 2, group F, member 2",nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|neuron migration|maternal placenta development|negative regulation of endothelial cell proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|skeletal muscle tissue development|fertilization|anterior/posterior pattern specification|radial pattern formation|negative regulation of endothelial cell migration|intracellular receptor signaling pathway|forebrain development|steroid hormone mediated signaling pathway|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|blood vessel morphogenesis|limb development|placenta blood vessel development|trophoblast giant cell differentiation|regulation of transcription involved in lymphatic endothelial cell fate commitment|",retinoic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|zinc ion binding|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|,10,1.3,2.89,10,0,0,1.2,1.42,1.42,0.586,0,0,-0.2,3
ENSMUSG00000024182,AXIN1,axin 1,nucleus|cytoplasm|cytoplasm|Golgi apparatus|cytoplasmic microtubule|plasma membrane|plasma membrane|cell cortex|postsynaptic density|postsynaptic density|membrane|cytoplasmic membrane-bounded vesicle|lateral plasma membrane|beta-catenin destruction complex|beta-catenin destruction complex|cytoplasmic vesicle|protein complex|perinuclear region of cytoplasm|cell periphery|,"protein polyubiquitination|in utero embryonic development|in utero embryonic development|optic placode formation|regulation of protein phosphorylation|positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|nucleocytoplasmic transport|apoptotic process|activation of JUN kinase activity|multicellular organismal development|determination of left/right symmetry|sensory perception of sound|adult walking behavior|cell death|dorsal/ventral axis specification|dorsal/ventral axis specification|dorsal/ventral pattern formation|dorsal/ventral pattern formation|Wnt signaling pathway|Wnt signaling pathway|Wnt signaling pathway|hemoglobin metabolic process|forebrain anterior/posterior pattern specification|Wnt-activated signaling pathway involved in forebrain neuron fate commitment|protein catabolic process|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|olfactory placode formation|cytoplasmic microtubule organization|positive regulation of protein ubiquitination|positive regulation of protein ubiquitination|positive regulation of protein ubiquitination|activation of protein kinase activity|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|erythrocyte homeostasis|negative regulation of transcription elongation from RNA polymerase II promoter|regulation of catenin import into nucleus|post-anal tail morphogenesis|termination of G-protein coupled receptor signaling pathway|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|positive regulation of GTPase activity|cellular protein complex assembly|negative regulation of fat cell differentiation|positive regulation of protein catabolic process|positive regulation of protein kinase activity|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of JNK cascade|embryonic eye morphogenesis|axial mesoderm development|axial mesoderm formation|neurological system process|negative regulation of protein metabolic process|protein homooligomerization|protein homooligomerization|positive regulation of ubiquitin-protein transferase activity|positive regulation of ubiquitin-protein transferase activity|muscle cell development|canonical Wnt signaling pathway|canonical Wnt signaling pathway|embryonic skeletal joint morphogenesis|canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation|cellular response to organic cyclic compound|genetic imprinting|negative regulation of canonical Wnt signaling pathway|Wnt signaling pathway involved in somitogenesis|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|",p53 binding|signal transducer activity|GTPase activator activity|receptor binding|protein binding|beta-catenin binding|beta-catenin binding|beta-catenin binding|protein C-terminus binding|protein C-terminus binding|enzyme binding|protein kinase binding|protein kinase binding|protein domain specific binding|protein domain specific binding|ubiquitin protein ligase binding|ubiquitin protein ligase binding|protein complex scaffold|protein complex scaffold|identical protein binding|identical protein binding|protein homodimerization activity|protein self-association|SMAD binding|armadillo repeat domain binding|armadillo repeat domain binding|I-SMAD binding|I-SMAD binding|I-SMAD binding|R-SMAD binding|,9,-1,4,9,-0.1,0.0432,-0.9,1.42,-1.42,0.586,0,0,-2,0.4
ENSMUSG00000031570,PPAPDC1B,phosphatidic acid phosphatase type 2 domain containing 1B,cellular_component|membrane|integral component of membrane|,phospholipid dephosphorylation|,catalytic activity|phosphatidate phosphatase activity|hydrolase activity|,10,0,0,10,0.3,2.46,0.2,1.42,1.42,0.586,0,0,-0.4,2
ENSMUSG00000020241,COL6A2,"collagen, type VI, alpha 2",extracellular region|proteinaceous extracellular matrix|collagen trimer|extracellular space|membrane|extracellular matrix|extracellular matrix|sarcolemma|protein complex|extracellular vesicular exosome|,cell adhesion|protein heterotrimerization|,None,10,0.4,2.33,10,0,0,0.4,1.41,1.41,0.588,0,0,-0.7,1.8
ENSMUSG00000050379,6-Sep,septin 6,"chromosome, centromeric region|kinetochore|chromosome|cytoplasm|cytoskeleton|synaptic vesicle|septin complex|axon terminus|",cell cycle|cell division|,nucleotide binding|GTP binding|,8,-0.5,2.48,8,0,0,-0.3,1.41,-1.41,0.588,0,0,-1.5,1.7
ENSMUSG00000059891,TSKS,testis-specific serine kinase substrate,acrosomal vesicle|cytoplasm|centriole|centriole|cytoskeleton|cytoplasmic vesicle|,negative regulation of phosphatase activity|phosphorylation|,kinase activity|transferase activity|protein kinase binding|protein kinase binding|,10,-0.4,1.37,10,1.2,1.91,0.2,1.41,1.41,0.588,0,0,-0.8,2
ENSMUSG00000050812,AI314180,expressed sequence AI314180,proteasome complex|nucleus|cytoplasm|endosome|early endosome|late endosome|multivesicular body|endoplasmic reticulum|centrosome|cytoskeleton|membrane|cytoplasmic membrane-bounded vesicle|ER to Golgi transport vesicle|endocytic vesicle|cytoplasmic vesicle|,ER-associated ubiquitin-dependent protein catabolic process|,None,8,1.3,4.13,8,-0.8,0.2,1.2,1.41,1.41,0.588,0,0,-0.8,3
ENSMUSG00000015365,MOV10L1,Moloney leukemia virus 10-like 1,cytoplasm|,multicellular organismal development|muscle organ development|cell proliferation|negative regulation of cell cycle|,nucleotide binding|helicase activity|ATP binding|hydrolase activity|,10,0.2,0.446,10,1.3,2.72,0.3,1.41,1.41,0.588,0,0,-0.3,2
ENSMUSG00000039000,UBE3C,ubiquitin protein ligase E3C,nucleus|cytoplasm|,protein polyubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.8,3.89,10,0.2,0.784,-0.7,1.4,-1.4,0.589,0,0,-2,0.6
ENSMUSG00000029223,UCHL1,ubiquitin carboxy-terminal hydrolase L1,intracellular|cell|nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|cytosol|plasma membrane|membrane|axon|neuronal cell body|extracellular vesicular exosome|,response to ischemia|proteolysis|ubiquitin-dependent protein catabolic process|axonogenesis|axon target recognition|adult walking behavior|adult walking behavior|cell proliferation|protein deubiquitination|sensory perception of pain|axon transport of mitochondrion|eating behavior|negative regulation of MAP kinase activity|muscle fiber development|neuromuscular process|,cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|omega peptidase activity|hydrolase activity|ligase activity|alpha-2A adrenergic receptor binding|ubiquitin binding|ubiquitin binding|,9,-1,3.35,8,-0.1,0.00352,-0.2,1.4,-1.4,0.589,0,0,-2,0.6
ENSMUSG00000076744,TCRG-V7,"T cell receptor gamma, variable 7",None,None,None,10,-0.2,0.893,10,-0.2,0.617,-0.2,1.39,-1.39,0.591,0,0,-1.5,1.2
ENSMUSG00000030653,PDE2A,"phosphodiesterase 2A, cGMP-stimulated",intracellular|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrial matrix|endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|plasma membrane|plasma membrane|plasma membrane|membrane|axon|dendrite|presynaptic membrane|membrane raft|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|cAMP catabolic process|cAMP catabolic process|protein targeting to mitochondrion|signal transduction|metabolic process|metabolic process|positive regulation of gene expression|cAMP-mediated signaling|cAMP-mediated signaling|cAMP-mediated signaling|cGMP-mediated signaling|cGMP-mediated signaling|negative regulation of cAMP biosynthetic process|negative regulation of cAMP biosynthetic process|negative regulation of protein import into nucleus, translocation|cellular response to drug|cellular response to macrophage colony-stimulating factor stimulus|negative regulation of vascular permeability|positive regulation of vascular permeability|cGMP catabolic process|cGMP catabolic process|positive regulation of inflammatory response|establishment of endothelial barrier|cellular response to mechanical stimulus|cellular response to cGMP|cellular response to granulocyte macrophage colony-stimulating factor stimulus|","nucleotide binding|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|drug binding|hydrolase activity|cAMP binding|cAMP binding|cGMP binding|cGMP binding|cGMP binding|TPR domain binding|GAF domain binding|protein homodimerization activity|protein homodimerization activity|metal ion binding|",10,-0.2,0.265,10,-0.3,1.26,-0.3,1.38,-1.38,0.592,0,0,-1.8,0.6
ENSMUSG00000069917,HBA-A2,"hemoglobin alpha, adult chain 2",hemoglobin complex|membrane|cytosolic small ribosomal subunit|haptoglobin-hemoglobin complex|extracellular vesicular exosome|blood microparticle|,in utero embryonic development|erythrocyte development|,peroxidase activity|haptoglobin binding|,9,-0.4,2.9,9,0.2,0.758,-0.3,1.38,-1.38,0.592,0,0,-1.7,0.9
ENSMUSG00000027401,TGM3,"transglutaminase 3, E polypeptide",cornified envelope|cytoplasm|extrinsic component of cytoplasmic side of plasma membrane|extracellular vesicular exosome|,epidermis development|peptide cross-linking|peptide cross-linking|keratinization|hair cell differentiation|cell envelope organization|skin development|protein tetramerization|,"protein-glutamine gamma-glutamyltransferase activity|protein-glutamine gamma-glutamyltransferase activity|catalytic activity|catalytic activity|calcium ion binding|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,-1.4,0.348,10,-1.4,1.14,-1.4,1.38,-1.38,0.592,0,0,-3,0.3
ENSMUSG00000031822,GSE1,genetic suppressor element 1,cellular_component|,biological_process|,molecular_function|,9,0.1,0.103,9,-0.6,2.99,-0.4,1.38,-1.38,0.592,0,0,-1.9,0.7
ENSMUSG00000032440,TGFBR2,"transforming growth factor, beta receptor II",cytoplasm|cytosol|plasma membrane|integral component of plasma membrane|caveola|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|membrane raft|,patterning of blood vessels|vasculogenesis|in utero embryonic development|positive regulation of mesenchymal cell proliferation|lens development in camera-type eye|positive regulation of tolerance induction to self antigen|positive regulation of B cell tolerance induction|positive regulation of T cell tolerance induction|protein phosphorylation|protein phosphorylation|protein phosphorylation|receptor-mediated endocytosis|apoptotic process|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|common-partner SMAD protein phosphorylation|smoothened signaling pathway|gastrulation|brain development|heart development|negative regulation of cell proliferation|organ morphogenesis|positive regulation of epithelial cell migration|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|cell differentiation|lung development|activation of protein kinase activity|embryonic hemopoiesis|regulation of growth|regulation of cell proliferation|response to drug|myeloid dendritic cell differentiation|positive regulation of angiogenesis|positive regulation of smooth muscle cell proliferation|embryonic cranial skeleton morphogenesis|positive regulation of NK T cell differentiation|cartilage development|palate development|negative regulation of cardiac muscle cell proliferation|pathway-restricted SMAD protein phosphorylation|lung morphogenesis|bronchus development|bronchus morphogenesis|trachea morphogenesis|trachea formation|mammary gland morphogenesis|lung lobe morphogenesis|response to cholesterol|response to cholesterol|lens fiber cell apoptotic process|positive regulation of reactive oxygen species metabolic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|receptor activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta receptor activity, type II|protein binding|ATP binding|glycosaminoglycan binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase kinase binding|type I transforming growth factor beta receptor binding|type III transforming growth factor beta receptor binding|SMAD binding|SMAD binding|metal ion binding|transforming growth factor beta binding|transforming growth factor beta binding|",10,0.2,1.21,10,0.3,0.277,0.2,1.37,1.37,0.594,0,0,-1.8,1.2
ENSMUSG00000021236,ENTPD5,ectonucleoside triphosphate diphosphohydrolase 5,extracellular region|endoplasmic reticulum|extracellular vesicular exosome|,protein N-linked glycosylation|cell proliferation|regulation of phosphatidylinositol 3-kinase signaling|cell growth|positive regulation of glycolytic process|ATP metabolic process|'de novo' posttranslational protein folding|,guanosine-diphosphatase activity|hydrolase activity|nucleoside-diphosphatase activity|uridine-diphosphatase activity|,10,0.2,1.42,10,0.5,0.0533,0.2,1.36,1.36,0.595,0,0,-0.9,1.6
ENSMUSG00000028629,EXO5,exonuclease 5,nucleus|cytoplasm|cytosol|,"DNA catabolic process, exonucleolytic|DNA repair|cellular response to DNA damage stimulus|interstrand cross-link repair|","DNA binding|nuclease activity|exonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|single-stranded DNA 5'-3' exodeoxyribonuclease activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.7,1.4,10,-1.1,4.12,-1,1.36,-1.36,0.595,0,0,-2,1.1
ENSMUSG00000059921,UNC5C,unc-5 homolog C (C. elegans),plasma membrane|membrane|integral component of membrane|,apoptotic process|signal transduction|multicellular organismal development|axon guidance|brain development|regulation of cell migration|anterior/posterior axon guidance|netrin-activated signaling pathway|positive regulation of apoptotic process|,netrin receptor activity|protein binding|,10,0.6,2.22,10,-0.1,0.0181,0.5,1.35,1.35,0.597,0,0,-0.7,1.8
ENSMUSG00000026828,GALNT5,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5,Golgi apparatus|membrane|integral component of membrane|,None,"polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0.1,0.268,10,-0.4,3.01,-0.3,1.35,-1.35,0.597,0,0,-1.6,0.9
ENSMUSG00000040287,STAC3,SH3 and cysteine rich domain 3,cellular_component|,intracellular signal transduction|skeletal muscle fiber development|,identical protein binding|metal ion binding|,10,0.3,2.03,10,-0.3,0.973,0.2,1.35,1.35,0.597,0,0,-1.2,1.4
ENSMUSG00000048251,BCL11B,B cell leukemia/lymphoma 11B,intracellular|nucleus|neuron part|,"keratinocyte development|epithelial cell morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|axonogenesis|negative regulation of cell proliferation|post-embryonic development|regulation of gene expression|regulation of keratinocyte proliferation|regulation of lipid metabolic process|striatal medium spiny neuron differentiation|commitment of neuronal cell to specific neuron type in forebrain|central nervous system neuron differentiation|post-embryonic camera-type eye development|T cell differentiation in thymus|T cell receptor V(D)J recombination|odontogenesis of dentin-containing tooth|negative regulation of apoptotic process|positive T cell selection|skin development|regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|alpha-beta T cell differentiation|thymus development|olfactory bulb axon guidance|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|protein binding|sequence-specific DNA binding|metal ion binding|,10,0.2,0.265,10,0.3,1.28,0.2,1.34,1.34,0.598,0,0,-0.8,1.8
ENSMUSG00000026321,TNFRSF11A,"tumor necrosis factor receptor superfamily, member 11a, NFKB activator",plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,ossification|adaptive immune response|multicellular organismal development|programmed cell death|osteoclast differentiation|response to lipopolysaccharide|tumor necrosis factor-mediated signaling pathway|response to cytokine|response to tumor necrosis factor|positive regulation of JUN kinase activity|lymph node development|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|circadian temperature homeostasis|mammary gland alveolus development|response to interleukin-1|positive regulation of fever generation by positive regulation of prostaglandin secretion|TNFSF11-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling|,transmembrane signaling receptor activity|tumor necrosis factor-activated receptor activity|protein binding|cytokine binding|metal ion binding|,10,-0.1,0.0813,10,-0.4,1.84,-0.3,1.34,-1.34,0.598,0,0,-1.7,0.9
ENSMUSG00000011114,TBRG1,transforming growth factor beta regulated gene 1,nucleus|nucleus|intracellular membrane-bounded organelle|,DNA replication|DNA replication|cell cycle|cell cycle arrest|cell cycle arrest|negative regulation of cell proliferation|negative regulation of cell proliferation|nucleolus to nucleoplasm transport|nucleolus to nucleoplasm transport|protein stabilization|protein stabilization|,molecular_function|,10,-0.2,0.618,10,-0.2,0.84,-0.2,1.34,-1.34,0.598,0,0,-1.7,0.8
ENSMUSG00000055884,FANCM,"Fanconi anemia, complementation group M",nucleus|Fanconi anaemia nuclear complex|FANCM-MHF complex|,resolution of meiotic recombination intermediates|DNA metabolic process|DNA repair|cellular response to DNA damage stimulus|replication fork processing|,nucleotide binding|nucleic acid binding|DNA binding|chromatin binding|helicase activity|nuclease activity|ATP binding|hydrolase activity|,10,0,0,10,0.9,3.14,0.2,1.34,1.34,0.598,0,0,-0.3,1.9
ENSMUSG00000019987,ARG1,"arginase, liver",extracellular space|nucleus|cytoplasm|mitochondrial outer membrane|neuron projection|neuronal cell body|extracellular vesicular exosome|,urea cycle|positive regulation of endothelial cell proliferation|arginine metabolic process|regulation of L-arginine import|arginine catabolic process to ornithine|collagen biosynthetic process|protein homotrimerization|,"arginase activity|arginase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines|manganese ion binding|metal ion binding|",10,-0.1,0.083,10,-0.2,1.37,-0.2,1.33,-1.33,0.6,0,0,-1.6,1
ENSMUSG00000078937,CPT1B,"carnitine palmitoyltransferase 1b, muscle",mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|fatty acid metabolic process|transport|long-chain fatty acid transport|long-chain fatty acid transport|,"carnitine O-palmitoyltransferase activity|carnitine O-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.3,2.38,10,0,0,0.3,1.32,1.32,0.601,0,0,-1,1.7
ENSMUSG00000031388,NAA10,"N(alpha)-acetyltransferase 10, NatA catalytic subunit",intracellular|nucleus|nucleolus|cytoplasm|cytoplasm|membrane|NatA complex|,N-terminal protein amino acid acetylation|,"dihydrolipoamide branched chain acyltransferase activity|peptide alpha-N-acetyltransferase activity|sterol O-acyltransferase activity|protein binding|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|ribosome binding|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,-0.2,0.253,10,-0.4,1.39,-0.2,1.32,-1.32,0.601,0,0,-1.7,0.8
ENSMUSG00000023953,POLH,"polymerase (DNA directed), eta (RAD 30 related)",nucleus|,DNA synthesis involved in DNA repair|DNA replication|DNA-dependent DNA replication|DNA repair|pyrimidine dimer repair|postreplication repair|cellular response to DNA damage stimulus|response to UV-C|DNA biosynthetic process|,DNA binding|damaged DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,-0.5,2.06,10,-0.1,0.0632,-0.4,1.32,-1.32,0.601,0,0,-1.9,0.6
ENSMUSG00000027832,PTX3,pentraxin related gene,extracellular region|extracellular space|,response to yeast|opsonization|innate immune response|positive regulation of nitric oxide biosynthetic process|negative regulation of viral entry into host cell|positive regulation of phagocytosis|negative regulation of exo-alpha-sialidase activity|negative regulation of glycoprotein metabolic process|,complement component C1q binding|(1->3)-beta-D-glucan binding|virion binding|,10,-0.2,0.574,10,-0.3,0.907,-0.2,1.31,-1.31,0.603,0,0,-1.3,1.6
ENSMUSG00000049191,RGAG4,retrotransposon gag domain containing 4,cellular_component|,biological_process|,molecular_function|,10,-0.4,2.76,10,0.3,2.02,0.2,1.3,1.3,0.605,0,0,-1.4,1.2
ENSMUSG00000036446,LUM,lumican,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|fibrillar collagen trimer|extracellular space|extracellular matrix|extracellular vesicular exosome|,visual perception|collagen fibril organization|positive regulation of transcription from RNA polymerase II promoter|,collagen binding|,10,1.1,4.53,10,-0.8,0.536,1.1,1.3,1.3,0.605,0,0,-1,2
ENSMUSG00000020218,WIF1,Wnt inhibitory factor 1,extracellular region|,multicellular organismal development|Wnt signaling pathway|negative regulation of Wnt signaling pathway|positive regulation of fat cell differentiation|,Wnt-protein binding|,10,0,0,10,0.9,3.8,0.3,1.29,1.29,0.607,0,0,-0.4,2
ENSMUSG00000026389,STEAP3,STEAP family member 3,cell|endosome|multivesicular body|plasma membrane|membrane|integral component of membrane|,transport|ion transport|iron ion transport|apoptotic process|cell cycle|protein secretion|protein secretion|protein secretion|copper ion import|copper ion import|positive regulation of apoptotic process|iron ion homeostasis|oxidation-reduction process|oxidation-reduction process|ferric iron import into cell|ferric iron import into cell|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|exosomal secretion|,ferric-chelate reductase activity|ferric-chelate reductase activity|cupric reductase activity|oxidoreductase activity|metal ion binding|ferric-chelate reductase (NADPH) activity|ferric-chelate reductase (NADPH) activity|,10,0.2,1.23,10,0.1,0.299,0.2,1.29,1.29,0.607,0,0,-1,1.6
ENSMUSG00000067158,COL4A4,"collagen, type IV, alpha 4",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type IV trimer|collagen type IV trimer|basement membrane|basal lamina|,glomerular basement membrane development|glomerular basement membrane development|,extracellular matrix structural constituent|extracellular matrix structural constituent|,10,0.1,0.551,10,0.2,0.968,0.2,1.28,1.28,0.608,0,0,-1.3,1.4
ENSMUSG00000017929,B4GALT5,"UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5",Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,carbohydrate metabolic process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.2,1.23,10,0.1,0.2,0.2,1.27,1.27,0.61,0,0,-0.7,1.8
ENSMUSG00000031740,MMP2,matrix metallopeptidase 2,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|nucleus|cytoplasm|cytoplasm|mitochondrion|plasma membrane|membrane|sarcomere|extracellular matrix|,angiogenesis|ovarian follicle development|response to hypoxia|response to hypoxia|blood vessel maturation|intramembranous ossification|proteolysis|proteolysis|response to oxidative stress|negative regulation of cell adhesion|embryo implantation|response to mechanical stimulus|peripheral nervous system axon regeneration|cell migration|positive regulation of cell migration|collagen catabolic process|collagen catabolic process|response to drug|response to hydrogen peroxide|positive regulation of apoptotic process|response to estrogen|positive regulation of innate immune response|negative regulation of vasoconstriction|skeletal system morphogenesis|tissue remodeling|face morphogenesis|bone trabecula formation|prostate gland epithelium morphogenesis|cellular response to amino acid stimulus|cellular response to estradiol stimulus|,fibronectin binding|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.2,0.564,10,-0.2,0.817,-0.2,1.27,-1.27,0.61,0,0,-1.7,0.9
ENSMUSG00000026786,APBB1IP,"amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein",cytoplasm|cytoskeleton|plasma membrane|membrane|cell junction|cell projection|,signal transduction|,None,10,0.3,1.54,10,0.1,0.0519,0.3,1.27,1.27,0.61,0,0,-0.8,1.7
ENSMUSG00000024087,CYP1B1,"cytochrome P450, family 1, subfamily b, polypeptide 1",nucleus|mitochondrion|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,angiogenesis|trabecular meshwork development|DNA modification|cellular aromatic compound metabolic process|cellular aromatic compound metabolic process|cellular aromatic compound metabolic process|xenobiotic metabolic process|nitric oxide biosynthetic process|cell adhesion|steroid metabolic process|estrogen metabolic process|negative regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to oxidative stress|toxin metabolic process|response to toxic substance|positive regulation vascular endothelial growth factor production|positive regulation of smooth muscle cell migration|arachidonic acid metabolic process|collagen fibril organization|negative regulation of cell migration|negative regulation of NF-kappaB transcription factor activity|negative regulation of cell adhesion mediated by integrin|benzene-containing compound metabolic process|retinol metabolic process|retinal metabolic process|positive regulation of apoptotic process|endothelial cell migration|positive regulation of translation|positive regulation of angiogenesis|positive regulation of JAK-STAT cascade|membrane lipid catabolic process|blood vessel morphogenesis|oxidation-reduction process|retina vasculature development in camera-type eye|retinal blood vessel morphogenesis|cellular response to hydrogen peroxide|cellular response to organic cyclic compound|endothelial cell-cell adhesion|positive regulation of gene expression involved in extracellular matrix organization|regulation of reactive oxygen species metabolic process|positive regulation of reactive oxygen species metabolic process|positive regulation of DNA biosynthetic process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|metal ion binding|aromatase activity|",10,0.1,0.135,10,0.3,1.52,0.2,1.26,1.26,0.611,0,0,-0.8,1.7
ENSMUSG00000001036,EPN2,epsin 2,nucleus|cytoplasm|Golgi apparatus|clathrin coat of endocytic vesicle|intracellular membrane-bounded organelle|,in utero embryonic development|endocytosis|Notch signaling pathway|regulation of endocytosis|embryonic organ development|,lipid binding|,10,0.3,1.16,10,0.2,0.274,0.2,1.26,1.26,0.611,0,0,-0.9,1.6
ENSMUSG00000046561,ARSJ,arylsulfatase J,cellular_component|extracellular region|,metabolic process|,catalytic activity|sulfuric ester hydrolase activity|hydrolase activity|alkyl sulfatase activity|endosulfan hemisulfate sulfatase activity|endosulfan sulfate hydrolase activity|metal ion binding|,8,0.2,0.482,8,0.4,1.1,0.3,1.25,1.25,0.613,0,0,-0.7,1.9
ENSMUSG00000024012,MTCH1,mitochondrial carrier homolog 1 (C. elegans),mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|,None,10,0.9,0.034,10,-1,4.18,-0.9,1.24,-1.24,0.615,0,0,-2,1
ENSMUSG00000027699,ECT2,ect2 oncogene,nucleus|nucleus|cytoplasm|cytoplasm|cytoskeleton|cell-cell junction|tight junction|cell junction|midbody|cleavage furrow|mitotic spindle|centralspindlin complex|,cell morphogenesis|cytokinesis|transport|cell cycle|signal transduction|nervous system development|protein transport|cell differentiation|activation of protein kinase activity|positive regulation of Rho GTPase activity|positive regulation of cytokinesis|activation of Rho GTPase activity|activation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of protein import into nucleus|positive regulation of apoptotic process|positive regulation of Cdc42 GTPase activity|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of neuron differentiation|regulation of protein kinase activity|protein homooligomerization|cell division|regulation of attachment of spindle microtubules to kinetochore|cellular response to hydrogen peroxide|tight junction assembly|cellular response to calcium ion|cellular response to ionizing radiation|,signal transducer activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|Rho GTPase binding|protein homodimerization activity|,7,-0.5,0.633,6,0.5,1.78,0.4,1.24,1.24,0.615,0,0,-1.3,1.9
ENSMUSG00000054021,SIRT5,sirtuin 5,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial intermembrane space|mitochondrial matrix|cytosol|cytosol|,peptidyl-lysine demalonylation|peptidyl-lysine demalonylation|protein desuccinylation|protein desuccinylation|peptidyl-lysine desuccinylation|peptidyl-lysine desuccinylation|negative regulation of reactive oxygen species metabolic process|,"histone deacetylase activity|protein binding|zinc ion binding|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|protein-malonyllysine demalonylase activity|protein-malonyllysine demalonylase activity|protein-succinyllysine desuccinylase activity|protein-succinyllysine desuccinylase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|metal ion binding|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|NAD+ binding|",10,0,0,10,0.3,1.46,0.3,1.23,1.23,0.616,0,0,-0.6,2
ENSMUSG00000040061,PLCB2,"phospholipase C, beta 2",cytoplasm|Golgi apparatus|cytosol|plasma membrane|G-protein beta/gamma-subunit complex|,detection of chemical stimulus involved in sensory perception of bitter taste|lipid metabolic process|signal transduction|lipid catabolic process|intracellular signal transduction|sensory perception of bitter taste|,phosphatidylinositol phospholipase C activity|phospholipase C activity|signal transducer activity|calcium ion binding|phospholipid binding|phosphoric diester hydrolase activity|hydrolase activity|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,0.9,2.16,10,0.1,0.183,0.8,1.23,1.23,0.616,0,0,-1.7,1.7
ENSMUSG00000020953,COCH,coagulation factor C homolog (Limulus polyphemus),extracellular region|proteinaceous extracellular matrix|extracellular vesicular exosome|,sensory perception of sound|regulation of cell shape|defense response to bacterium|positive regulation of innate immune response|,protein binding|,10,0.3,1.36,10,-0.1,0.0208,0.3,1.23,1.23,0.616,0,0,-0.5,1.9
ENSMUSG00000028678,KIF2C,kinesin family member 2C,"chromosome, centromeric region|chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|cytoskeleton|kinesin complex|microtubule|microtubule cytoskeleton|membrane|microtubule plus-end|",microtubule-based movement|microtubule depolymerization|cell cycle|chromosome segregation|mitotic nuclear division|establishment or maintenance of microtubule cytoskeleton polarity|cell division|regulation of chromosome segregation|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|microtubule plus-end binding|,10,0.3,1.35,10,0.1,0.13,0.2,1.22,1.22,0.618,0,0,-0.9,1.7
ENSMUSG00000028974,DFFA,"DNA fragmentation factor, alpha subunit",nuclear chromatin|nuclear chromatin|intracellular|nucleus|cytoplasm|cytosol|,apoptotic process|positive regulation of apoptotic process|thymocyte apoptotic process|negative regulation of execution phase of apoptosis|negative regulation of execution phase of apoptosis|negative regulation of apoptotic DNA fragmentation|negative regulation of apoptotic DNA fragmentation|,protein binding|,10,0.6,2.81,10,0,0,0.2,1.22,1.22,0.618,0,0,-0.5,1.9
ENSMUSG00000037820,TGM2,"transglutaminase 2, C polypeptide",proteinaceous extracellular matrix|cytoplasm|mitochondrion|endoplasmic reticulum|cytosol|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,blood vessel remodeling|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|peptide cross-linking|isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine|negative regulation of endoplasmic reticulum calcium ion concentration|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|apoptotic cell clearance|positive regulation of cell adhesion|positive regulation of smooth muscle cell proliferation|positive regulation of inflammatory response|protein homooligomerization|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|positive regulation of mitochondrial calcium ion concentration|branching involved in salivary gland morphogenesis|salivary gland cavitation|,"protein-glutamine gamma-glutamyltransferase activity|protein-glutamine gamma-glutamyltransferase activity|calcium ion binding|GTP binding|GTP binding|transaminase activity|transferase activity|transferase activity, transferring acyl groups|protein domain specific binding|metal ion binding|",10,0.4,1.58,10,-0.2,0.187,0.2,1.22,1.22,0.618,0,0,-1,1.6
ENSMUSG00000078762,HAUS5,"HAUS augmin-like complex, subunit 5",cytoplasm|centrosome|cytoskeleton|microtubule|HAUS complex|,cell cycle|mitotic nuclear division|spindle assembly|centrosome organization|cell division|,molecular_function|,8,1.3,3.58,8,0.2,0.256,1.2,1.22,1.22,0.618,0,0,-1.7,2.8
ENSMUSG00000038437,MLLT6,"myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0.6,2.47,0.4,1.21,1.21,0.619,0,0,-0.4,1.8
ENSMUSG00000037849,GM4955,predicted gene 4955,None,None,None,10,-0.2,1.09,10,0.4,1.49,0.5,1.21,1.21,0.619,0,0,-0.6,1.9
ENSMUSG00000024172,ST6GAL2,"beta galactoside alpha 2,6 sialyltransferase 2",cellular_component|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|N-acetylneuraminate metabolic process|protein glycosylation|oligosaccharide metabolic process|sialylation|sialylation|,"catalytic activity|beta-galactoside alpha-2,6-sialyltransferase activity|beta-galactoside alpha-2,6-sialyltransferase activity|sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",9,0.9,1.16,9,0.3,0.601,0.4,1.21,1.21,0.619,0,0,-0.5,2
ENSMUSG00000027104,ATF2,activating transcription factor 2,nucleus|nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|site of double-strand break|,"outflow tract morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to osmotic stress|cellular response to DNA damage stimulus|histone acetylation|intra-S DNA damage checkpoint|positive regulation of transforming growth factor beta2 production|fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of sequence-specific DNA binding transcription factor activity|adipose tissue development|positive regulation of mitochondrial membrane permeability involved in apoptotic process|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II activating transcription factor binding|nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|histone acetyltransferase activity|protein binding|cAMP response element binding protein binding|transferase activity|protein kinase binding|cAMP response element binding|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,-0.3,1.54,10,-1.1,0.768,-0.2,1.21,-1.21,0.619,0,0,-1.8,1.5
ENSMUSG00000041378,CLDN5,claudin 5,plasma membrane|cell-cell junction|tight junction|membrane|integral component of membrane|cell junction|paranode region of axon|Schmidt-Lanterman incisure|extracellular vesicular exosome|,single organismal cell-cell adhesion|myelination|,structural molecule activity|protein binding|,10,-0.6,1.85,10,-0.1,0.198,-0.4,1.2,-1.2,0.621,0,0,-1.9,0.6
ENSMUSG00000014402,TSG101,tumor susceptibility gene 101,ESCRT I complex|nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|endosome|early endosome|late endosome|plasma membrane|membrane|extracellular vesicular exosome|,"regulation of cell growth|cellular protein modification process|protein monoubiquitination|transport|cell cycle|cell cycle arrest|negative regulation of cell proliferation|endosome to lysosome transport|protein transport|viral process|cell differentiation|keratinocyte differentiation|regulation of growth|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|negative regulation of transcription, DNA-templated|viral budding|viral budding|cell division|regulation of RNA biosynthetic process|",transcription corepressor activity|protein binding|ligand-dependent nuclear receptor transcription coactivator activity|ubiquitin protein ligase binding|protein homodimerization activity|ubiquitin binding|calcium-dependent protein binding|,5,-0.4,1.5,5,1.1,3.25,1.1,1.2,1.2,0.621,0,0,-1.1,2
ENSMUSG00000028104,POLR3GL,polymerase (RNA) III (DNA directed) polypeptide G like,nuclear chromatin|nuclear chromatin|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|,transcription initiation from RNA polymerase III promoter|,RNA polymerase III activity|,10,1.2,3.86,9,0,0,0.2,1.18,1.18,0.625,0,0,-0.2,2
ENSMUSG00000026484,RNF2,ring finger protein 2,ubiquitin ligase complex|ubiquitin ligase complex|euchromatin|heterochromatin|sex chromatin|nucleus|nucleus|chromosome|nuclear body|PcG protein complex|PcG protein complex|PRC1 complex|MLL1 complex|,"negative regulation of transcription from RNA polymerase II promoter|mitotic cell cycle|gastrulation with mouth forming second|transcription, DNA-templated|regulation of transcription, DNA-templated|anterior/posterior axis specification|histone ubiquitination|histone ubiquitination|histone H2A monoubiquitination|histone H2A-K119 monoubiquitination|","chromatin binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|RING-like zinc finger domain binding|",10,0.3,0.573,10,0.4,0.816,0.3,1.18,1.18,0.625,0,0,-1.5,1.4
ENSMUSG00000028999,RINT1,RAD50 interactor 1,cytoplasm|endoplasmic reticulum|membrane|,transport|cell cycle|protein transport|vesicle-mediated transport|G2 DNA damage checkpoint|,None,10,0.6,1.93,10,0.1,0.0635,0.3,1.17,1.17,0.626,0,0,-0.9,1.9
ENSMUSG00000022496,TNFRSF17,"tumor necrosis factor receptor superfamily, member 17",membrane|integral component of membrane|,immune system process|,None,10,-0.2,0.812,10,-0.2,0.455,-0.2,1.17,-1.17,0.626,0,0,-1.7,0.9
ENSMUSG00000052572,DLG2,"discs, large homolog 2 (Drosophila)",cytoplasm|plasma membrane|membrane|cell junction|dendrite|neuronal cell body|juxtaparanode region of axon|juxtaparanode region of axon|synapse|postsynaptic membrane|,synaptic transmission|negative regulation of phosphatase activity|sensory perception of pain|receptor clustering|neuronal ion channel clustering|,protein binding|protein C-terminus binding|protein phosphatase binding|PDZ domain binding|protein heterodimerization activity|,10,0.4,0.564,10,0.5,0.731,0.4,1.17,1.17,0.626,0,0,-1.2,1.6
ENSMUSG00000027193,API5,apoptosis inhibitor 5,nucleus|spliceosomal complex|cytoplasm|membrane|,apoptotic process|negative regulation of apoptotic process|negative regulation of fibroblast apoptotic process|,fibroblast growth factor binding|poly(A) RNA binding|,10,-0.4,1.55,10,0.5,1.66,0.4,1.16,1.16,0.628,0,0,-1.1,1.6
ENSMUSG00000037544,DLGAP5,"discs, large (Drosophila) homolog-associated protein 5",nucleus|cytoplasm|microtubule organizing center|cytoskeleton|spindle pole centrosome|,mitotic M phase|cell cycle|cell-cell signaling|dephosphorylation|,phosphoprotein phosphatase activity|,10,1.3,3.56,10,-0.1,0.286,0.3,1.16,1.16,0.628,0,0,-0.4,2.9
ENSMUSG00000061589,DOT1L,"DOT1-like, histone H3 methyltransferase (S. cerevisiae)",nucleus|,chromatin modification|histone methylation|peptidyl-lysine methylation|methylation|histone lysine methylation|regulation of JAK-STAT cascade|regulation of transcription regulatory region DNA binding|,transcription factor binding|methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity|,10,-0.4,1.58,10,-0.1,0.267,-0.3,1.16,-1.16,0.628,0,0,-1.7,0.7
ENSMUSG00000032968,INHA,inhibin alpha,photoreceptor outer segment|photoreceptor inner segment|extracellular region|extracellular space|cytoplasm|inhibin-betaglycan-ActRII complex|neuronal cell body|inhibin A complex|,ovarian follicle development|male gonad development|regulation of cell proliferation|hemoglobin biosynthetic process|negative regulation of follicle-stimulating hormone secretion|regulation of cell cycle|,receptor binding|hormone activity|growth factor activity|inhibin binding|protein heterodimerization activity|,9,0,0,9,0.8,2.35,0.3,1.16,1.16,0.628,0,0,-0.4,2
ENSMUSG00000031843,MPHOSPH6,M phase phosphoprotein 6,exosome (RNase complex)|exosome (RNase complex)|nucleus|nucleolus|cytoplasm|,maturation of 5.8S rRNA|rRNA processing|,molecular_function|RNA binding|,10,-0.1,0.0738,9,0.5,2.25,0.4,1.16,1.16,0.628,0,0,-1.2,1.6
ENSMUSG00000029632,NDUFA4,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex IV|mitochondrial respiratory chain complex IV|membrane|extracellular vesicular exosome|respiratory chain|,transport|oxidation-reduction process|hydrogen ion transmembrane transport|,cytochrome-c oxidase activity|protein complex binding|,9,-0.8,2.79,9,-0.1,0.0523,-0.3,1.16,-1.16,0.628,0,0,-2,0.4
ENSMUSG00000024112,CACNA1H,"calcium channel, voltage-dependent, T type, alpha 1H subunit",nucleus|cytoplasm|voltage-gated calcium channel complex|caveola|membrane|integral component of membrane|dendrite|sarcolemma|perikaryon|,transport|ion transport|calcium ion transport|sensory perception of pain|aldosterone biosynthetic process|cortisol biosynthetic process|regulation of ion transmembrane transport|regulation of membrane potential|positive regulation of calcium ion-dependent exocytosis|transmembrane transport|calcium ion import|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|positive regulation of acrosome reaction|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|low voltage-gated calcium channel activity|low voltage-gated calcium channel activity|low voltage-gated calcium channel activity|metal ion binding|scaffold protein binding|,10,1,4.11,10,0,0,1,1.15,1.15,0.629,0,0,-0.4,2
ENSMUSG00000021186,FBLN5,fibulin 5,extracellular region|extracellular space|extracellular matrix|extracellular matrix|extracellular vesicular exosome|elastic fiber|,cell adhesion|extracellular matrix organization|protein localization to cell surface|elastic fiber assembly|regulation of removal of superoxide radicals|,calcium ion binding|protein C-terminus binding|,10,0.5,1.36,10,-0.2,0.529,-0.2,1.15,-1.15,0.629,0,0,-1.6,1.3
ENSMUSG00000039396,NEIL3,nei like 3 (E. coli),nucleus|nucleus|,"DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|DNA repair|base-excision repair|nucleotide-excision repair|cellular response to DNA damage stimulus|metabolic process|","bubble DNA binding|purine-specific mismatch base pair DNA N-glycosylase activity|nucleic acid binding|DNA binding|damaged DNA binding|double-stranded DNA binding|single-stranded DNA binding|single-stranded DNA binding|catalytic activity|DNA-(apurinic or apyrimidinic site) lyase activity|DNA-(apurinic or apyrimidinic site) lyase activity|uracil DNA N-glycosylase activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hydrolase activity, hydrolyzing N-glycosyl compounds|lyase activity|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA-3-methylbase glycosylase activity|metal ion binding|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,-0.1,0.332,10,-0.3,1.1,-0.2,1.15,-1.15,0.629,0,0,-1.7,0.9
ENSMUSG00000028005,GUCY1B3,"guanylate cyclase 1, soluble, beta 3","cytoplasm|guanylate cyclase complex, soluble|intracellular membrane-bounded organelle|protein complex|",cGMP biosynthetic process|nitric oxide mediated signal transduction|cyclic nucleotide biosynthetic process|intracellular signal transduction|,nucleotide binding|guanylate cyclase activity|GTP binding|lyase activity|phosphorus-oxygen lyase activity|heme binding|ion binding|metal ion binding|protein heterodimerization activity|Hsp90 protein binding|,10,-0.3,1.97,10,0.2,0.372,-0.2,1.14,-1.14,0.631,0,0,-1.6,1
ENSMUSG00000041358,NUTM1,"NUT midline carcinoma, family member 1",cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.4,1.63,10,1.5,2.43,0.7,1.14,1.14,0.631,0,0,-1.1,3
ENSMUSG00000025747,TYMS,thymidylate synthase,nucleus|nucleolus|cytoplasm|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|membrane|,dTMP biosynthetic process|nucleotide biosynthetic process|methylation|dUMP metabolic process|,nucleotide binding|mRNA binding|thymidylate synthase activity|folic acid binding|drug binding|methyltransferase activity|transferase activity|protein homodimerization activity|cofactor binding|,3,0.6,2.46,4,0,0,0.4,1.13,1.13,0.633,0,0,-1.5,2
ENSMUSG00000017491,RARB,"retinoic acid receptor, beta",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|ureteric bud development|glandular epithelial cell development|outflow tract septum morphogenesis|retinal pigment epithelium development|growth plate cartilage development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|negative regulation of cell proliferation|striatum development|neurogenesis|regulation of myelination|negative regulation of chondrocyte differentiation|embryonic hindlimb morphogenesis|multicellular organism growth|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of programmed cell death|steroid hormone mediated signaling pathway|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic eye morphogenesis|retinoic acid receptor signaling pathway|embryonic digestive tract development|ventricular cardiac muscle cell differentiation|retina development in camera-type eye|bone development|negative regulation of cartilage development|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|retinoic acid receptor activity|drug binding|zinc ion binding|protein complex binding|sequence-specific DNA binding|metal ion binding|retinoid X receptor binding|,9,-0.2,0.641,10,-1.2,1.86,-0.2,1.13,-1.13,0.633,0,0,-2,0.5
ENSMUSG00000095795,PARK2,"Parkinson disease (autosomal recessive, juvenile) 2, parkin",Golgi membrane|ubiquitin ligase complex|intracellular|nucleus|cytoplasm|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|synaptic vesicle|postsynaptic density|membrane|aggresome|cell junction|cytoplasmic vesicle|cell projection|neuron projection|protein complex|membrane raft|synapse|postsynaptic membrane|perinuclear region of cytoplasm|,"protein polyubiquitination|mitochondrion degradation|negative regulation of protein phosphorylation|synaptic transmission, dopaminergic|startle response|transcription, DNA-templated|regulation of transcription, DNA-templated|ubiquitin-dependent protein catabolic process|protein monoubiquitination|autophagy|response to unfolded protein|learning|locomotory behavior|cell death|adult locomotory behavior|regulation of autophagy|protein ubiquitination|protein ubiquitination|protein metabolic process|negative regulation of actin filament bundle assembly|negative regulation of glucokinase activity|synaptic transmission, glutamatergic|norepinephrine metabolic process|dopamine metabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of neuron apoptotic process|cellular protein catabolic process|negative regulation of insulin secretion|regulation of neurotransmitter secretion|regulation of synaptic transmission|dopamine uptake involved in synaptic transmission|protein autoubiquitination|negative regulation of cell death|protein K63-linked ubiquitination|aggresome assembly|protein K48-linked ubiquitination|neuron death|negative regulation of release of cytochrome c from mitochondria|negative regulation of neuron death|regulation of reactive oxygen species metabolic process|","ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|kinase binding|protein kinase binding|PDZ domain binding|ubiquitin protein ligase binding|protein complex binding|identical protein binding|ubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|chaperone binding|ubiquitin protein ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|ubiquitin-specific protease binding|",8,-1,3.43,8,0.5,0.0845,-0.9,1.12,-1.12,0.635,0,0,-2,0.7
ENSMUSG00000036948,BC037034,cDNA sequence BC037034,cellular_component|,biological_process|,molecular_function|,10,0.8,3.17,10,0,0,0.6,1.11,1.11,0.636,0,0,-0.5,2
ENSMUSG00000032580,RBM5,RNA binding motif protein 5,nucleus|spliceosomal complex|,"spliceosomal complex assembly|regulation of alternative mRNA splicing, via spliceosome|mRNA processing|apoptotic process|RNA splicing|positive regulation of apoptotic process|",nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.1,0.123,10,-0.6,1.93,-0.2,1.11,-1.11,0.636,0,0,-1.7,1.3
ENSMUSG00000029790,CEP41,centrosomal protein 41,cytoplasm|centrosome|centriole|centriole|cytoskeleton|cilium|membrane|ciliary basal body|ciliary basal body|cell projection|primary cilium|primary cilium|,transport|protein transport|cell projection organization|cilium assembly|cilium assembly|,molecular_function|,10,0.2,0.156,10,0.4,1.44,0.3,1.11,1.11,0.636,0,0,-1.2,1.5
ENSMUSG00000090272,MNDAL,myeloid nuclear differentiation antigen like,nucleus|nucleus|nucleolus|cytoplasm|membrane|,negative regulation of cell growth|regulation of growth|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,10,0.2,0.391,10,1.3,2.75,0.3,1.11,1.11,0.636,0,0,-0.3,2
ENSMUSG00000017615,TNFAIP1,"tumor necrosis factor, alpha-induced protein 1 (endothelial)",nucleus|nucleolus|cytoplasm|endosome|Cul3-RING ubiquitin ligase complex|,DNA replication|cell migration|protein ubiquitination|negative regulation of Rho protein signal transduction|stress fiber assembly|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of DNA replication|protein homooligomerization|,ubiquitin-protein transferase activity|GTP-Rho binding|protein domain specific binding|,10,-0.3,1.66,10,0,0,-0.2,1.1,-1.1,0.638,0,0,-1.7,1
ENSMUSG00000033834,TPBPA,trophoblast specific protein alpha,extracellular region|intracellular|,JNK cascade|cellular response to organic cyclic compound|,molecular_function|cysteine-type peptidase activity|,10,-0.1,0.169,10,0.8,3.36,0.8,1.1,1.1,0.638,0,0,-0.5,1.9
ENSMUSG00000061315,NACA,nascent polypeptide-associated complex alpha polypeptide,nucleus|cytoplasm|extracellular vesicular exosome|,"cardiac ventricle development|transcription, DNA-templated|regulation of transcription, DNA-templated|transport|negative regulation of striated muscle cell apoptotic process|protein transport|skeletal muscle tissue regeneration|positive regulation of skeletal muscle tissue growth|regulation of skeletal muscle fiber development|myoblast migration|heart trabecula morphogenesis|negative regulation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of cell proliferation involved in heart morphogenesis|regulation of RNA biosynthetic process|",DNA binding|transcription coactivator activity|TBP-class protein binding|,10,-0.3,0.905,10,-0.1,0.376,-0.2,1.1,-1.1,0.638,0,0,-1.8,0.8
ENSMUSG00000031910,HAS3,hyaluronan synthase 3,membrane|integral component of membrane|hyaluranon cable|,"hyaluronan biosynthetic process|hyaluronan biosynthetic process|extracellular polysaccharide biosynthetic process|positive regulation of transcription, DNA-templated|extracellular matrix assembly|positive regulation of hyaluranon cable assembly|","transferase activity|transferase activity, transferring glycosyl groups|hyaluronan synthase activity|hyaluronan synthase activity|",10,0.3,0.28,10,1.3,2.47,0.4,1.1,1.1,0.638,0,0,-2.2,2
ENSMUSG00000033227,WNT6,"wingless-type MMTV integration site family, member 6",extracellular region|proteinaceous extracellular matrix|extracellular space|cell surface|extracellular matrix|,"branching involved in ureteric bud morphogenesis|signal transduction|cell-cell signaling|multicellular organismal development|axis specification|organ morphogenesis|positive regulation of gene expression|positive regulation of gene expression|Wnt signaling pathway|neuron differentiation|odontogenesis of dentin-containing tooth|cell fate commitment|positive regulation of transcription, DNA-templated|epithelial-mesenchymal cell signaling|positive regulation of tooth mineralization|nephron tubule formation|nephron tubule development|",receptor binding|frizzled binding|protein binding|,10,0.1,0.216,10,0.3,1.17,0.2,1.1,1.1,0.638,0,0,-0.9,1.7
ENSMUSG00000016308,UBE2A,ubiquitin-conjugating enzyme E2A,chromatin|nuclear chromatin|XY body|HULC complex|,in utero embryonic development|DNA repair|cellular response to DNA damage stimulus|positive regulation of cell proliferation|response to UV|histone H2A ubiquitination|protein autoubiquitination|maternal process involved in female pregnancy|protein K48-linked ubiquitination|protein K11-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|ubiquitin protein ligase binding|,10,0.4,0.864,10,0.2,0.416,0.3,1.09,1.09,0.64,0,0,-0.6,1.8
ENSMUSG00000026883,DAB2IP,disabled 2 interacting protein,intracellular|cytoplasm|cytoplasm|cytoplasm|plasma membrane|plasma membrane|membrane|endocytic vesicle|axon|intrinsic component of the cytoplasmic side of the plasma membrane|neuronal cell body membrane|cell projection|neuronal cell body|cerebellar mossy fiber|climbing fiber|extracellular vesicular exosome|parallel fiber|,"negative regulation of transcription from RNA polymerase II promoter|activation of MAPKKK activity|angiogenesis|negative regulation of protein phosphorylation|negative regulation of protein phosphorylation|immune system process|apoptotic process|response to stress|inflammatory response|response to unfolded protein|cell cycle|signal transduction|I-kappaB phosphorylation|activation of JUN kinase activity|multicellular organismal development|negative regulation of cell proliferation|extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of endothelial cell migration|negative regulation of endothelial cell migration|negative regulation of epithelial cell migration|negative regulation of epithelial to mesenchymal transition|positive regulation of neuron projection development|negative regulation of phosphatidylinositol 3-kinase signaling|negative regulation of angiogenesis|negative regulation of angiogenesis|cell motility involved in cerebral cortex radial glia guided migration|layer formation in cerebral cortex|negative regulation of cell growth|negative regulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of NF-kappaB transcription factor activity|regulation of ARF GTPase activity|positive regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|negative regulation of toll-like receptor 4 signaling pathway|negative regulation of GTPase activity|negative regulation of Ras GTPase activity|tube formation|tube formation|negative regulation of catenin import into nucleus|cellular response to vascular endothelial growth factor stimulus|cellular response to vascular endothelial growth factor stimulus|vascular endothelial growth factor receptor-2 signaling pathway|regulation of growth|negative regulation of epidermal growth factor receptor signaling pathway|positive regulation of apoptotic process|positive regulation of apoptotic process|regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|regulation of protein complex assembly|regulation of protein complex assembly|negative regulation of MAP kinase activity|positive regulation of MAPK cascade|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|negative regulation of phosphatidylinositol 3-kinase activity|cellular protein catabolic process|innate immune response|positive regulation of protein catabolic process|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|negative regulation of Ras protein signal transduction|negative regulation of Ras protein signal transduction|negative regulation of fibroblast proliferation|neuron projection morphogenesis|negative regulation of epithelial cell proliferation|regulation of small GTPase mediated signal transduction|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of G0 to G1 transition|negative regulation of ERK1 and ERK2 cascade|positive regulation of cell cycle arrest|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|cellular response to interleukin-1|cellular response to interleukin-1|cellular response to tumor necrosis factor|cellular response to tumor necrosis factor|cellular response to epidermal growth factor stimulus|negative regulation of protein serine/threonine kinase activity|negative regulation of protein serine/threonine kinase activity|positive regulation of protein serine/threonine kinase activity|positive regulation of protein serine/threonine kinase activity|negative regulation of canonical Wnt signaling pathway|positive regulation of synapse maturation|positive regulation of dendrite development|regulation of p38MAPK cascade|negative regulation of vascular endothelial growth factor signaling pathway|positive regulation of proteasomal protein catabolic process|negative regulation of cyclin catabolic process|positive regulation of neuron migration|positive regulation of apoptotic signaling pathway|",GTPase activator activity|Ras GTPase activator activity|Ras GTPase activator activity|death receptor binding|protein binding|SH3 domain binding|kinase binding|protein kinase binding|mitogen-activated protein kinase kinase binding|mitogen-activated protein kinase kinase kinase binding|phosphatidylinositol-3-phosphate binding|protein complex binding|signaling adaptor activity|phosphatidylinositol 3-kinase regulatory subunit binding|identical protein binding|protein homodimerization activity|vascular endothelial growth factor receptor 2 binding|phosphatidylinositol 3-kinase binding|protein N-terminus binding|protein phosphatase 2A binding|phosphatidylinositol-4-phosphate binding|14-3-3 protein binding|,10,0.7,0.461,10,0.4,0.909,0.3,1.09,1.09,0.64,0,0,-0.3,1.9
ENSMUSG00000063177,KLK1B27,kallikrein 1-related peptidase b27,nucleus|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.5,1.7,10,0.1,0.145,-0.4,1.07,-1.07,0.643,0,0,-1.5,1.7
ENSMUSG00000040627,AICDA,activation-induced cytidine deaminase,exosome (RNase complex)|nucleus|nucleus|cytoplasm|,mRNA processing|cytidine deamination|cytidine deamination|somatic diversification of immunoglobulins|somatic hypermutation of immunoglobulin genes|isotype switching|cellular response to lipopolysaccharide|DNA demethylation|negative regulation of methylation-dependent chromatin silencing|,"catalytic activity|cytidine deaminase activity|cytidine deaminase activity|cytidine deaminase activity|protein binding|zinc ion binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines|metal ion binding|",10,-0.2,0.672,10,-0.2,0.496,-0.2,1.07,-1.07,0.643,0,0,-1.2,1.6
ENSMUSG00000046020,POFUT1,protein O-fucosyltransferase 1,endoplasmic reticulum|membrane|,angiogenesis|somitogenesis|carbohydrate metabolic process|fucose metabolic process|protein O-linked glycosylation|Notch signaling pathway|nervous system development|heart development|fucosylation|protein O-linked fucosylation|,"fucosyltransferase activity|fucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|peptide-O-fucosyltransferase activity|",10,0,0,10,-0.4,1.61,-0.3,1.06,-1.06,0.645,0,0,-1.6,1.2
ENSMUSG00000033540,IDUA,"iduronidase, alpha-L-",lysosome|extracellular vesicular exosome|,cell morphogenesis|carbohydrate metabolic process|lysosome organization|metabolic process|dermatan sulfate catabolic process|limb morphogenesis|skeletal system morphogenesis|chemical homeostasis|,"L-iduronidase activity|hydrolase activity, hydrolyzing O-glycosyl compounds|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.4,0.877,10,0.4,0.256,0.4,1.05,1.05,0.647,0,0,-0.6,1.9
ENSMUSG00000063895,NUPL1,nucleoporin like 1,nucleus|nuclear pore|membrane|,transport|nucleocytoplasmic transport|protein transport|mRNA transport|,nucleocytoplasmic transporter activity|protein binding|,9,-0.6,1.58,10,0,0,-0.6,1.05,-1.05,0.647,0,0,-2,0.5
ENSMUSG00000035235,TRIM13,tripartite motif-containing 13,intracellular|cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|perinuclear endoplasmic reticulum|,signal transduction|positive regulation of cell death|positive regulation of macroautophagy|ER-associated ubiquitin-dependent protein catabolic process|negative regulation of viral transcription|positive regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|innate immune response|positive regulation of NF-kappaB transcription factor activity|protein autoubiquitination|negative regulation of viral release from host cell|,"ubiquitin-protein transferase activity|signal transducer activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,1.64,10,0,0,0.2,1.05,1.05,0.647,0,0,-1.6,1.3
ENSMUSG00000034485,UACA,uveal autoantigen with coiled-coil domains and ankyrin repeats,intracellular|nucleus|nucleus|nuclear envelope|cytoplasm|cytoplasm|mitochondrion|cytosol|cytoskeleton|membrane|apoptosome|perinuclear region of cytoplasm|extracellular vesicular exosome|,intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to oxidative stress|response to UV|positive regulation of protein import into nucleus|negative regulation of NF-kappaB import into nucleus|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of inflammatory response|,protein binding|,10,-0.2,1.6,10,0,0,-0.2,1.04,-1.04,0.649,0,0,-1.9,0.7
ENSMUSG00000019505,UBB,ubiquitin B,nucleus|cytoplasm|,male meiosis I|female meiosis I|male gonad development|female gonad development|ubiquitin homeostasis|ubiquitin homeostasis|hypothalamus gonadotrophin-releasing hormone neuron development|adipose tissue development|fat pad development|seminiferous tubule development|energy homeostasis|,None,8,0,0,9,-0.4,2.28,-0.3,1.04,-1.04,0.649,0,0,-1.6,1.2
ENSMUSG00000029166,MAPRE3,"microtubule-associated protein, RP/EB family, member 3",cytoplasm|cytoplasm|cytoskeleton|microtubule|cytoplasmic microtubule|microtubule cytoskeleton|microtubule cytoskeleton|midbody|microtubule plus-end|perinuclear region of cytoplasm|,"cell cycle|mitotic nuclear division|positive regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of transcription, DNA-templated|cell division|positive regulation of microtubule plus-end binding|",protein binding|microtubule binding|,10,-0.8,3.38,10,0.2,0.273,0.2,1.04,1.04,0.649,0,0,-1.9,1.2
ENSMUSG00000024238,ZEB1,zinc finger E-box binding homeobox 1,nucleus|nucleus|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|pattern specification process|nervous system development|central nervous system development|negative regulation of cell proliferation|regulation of mesenchymal cell proliferation|regulation of transforming growth factor beta receptor signaling pathway|cell differentiation|negative regulation of epithelial cell differentiation|regulation of T cell differentiation in thymus|positive regulation of neuron differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|organ development|embryonic camera-type eye morphogenesis|embryonic morphogenesis|embryonic skeletal system morphogenesis|semicircular canal morphogenesis|regulation of smooth muscle cell differentiation|cartilage development|cellular response to amino acid stimulus|cochlea morphogenesis|",nucleic acid binding|DNA binding|chromatin binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|metal ion binding|E-box binding|,10,-0.7,1.87,10,0.2,0.565,0.2,1.04,1.04,0.649,0,0,-1.6,1.5
ENSMUSG00000027339,RASSF2,Ras association (RalGDS/AF-6) domain family member 2,nucleus|cytoplasm|,skeletal system development|ossification|cell cycle|signal transduction|epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade|regulation of osteoblast differentiation|regulation of osteoclast differentiation|bone remodeling|homeostasis of number of cells|regulation of NIK/NF-kappaB signaling|negative regulation of NIK/NF-kappaB signaling|,protein binding|,10,-0.4,2.38,10,0,0,-0.3,1.03,-1.03,0.651,0,0,-1.7,1
ENSMUSG00000032006,PDGFD,"platelet-derived growth factor, D polypeptide",extracellular region|extracellular space|membrane|extracellular vesicular exosome|,multicellular organismal development|cellular process|platelet-derived growth factor receptor signaling pathway|regulation of peptidyl-tyrosine phosphorylation|positive regulation of cell division|cellular response to amino acid stimulus|,platelet-derived growth factor receptor binding|growth factor activity|,10,0,0,10,0.5,1.49,0.4,1.03,1.03,0.651,0,0,-1.2,1.7
ENSMUSG00000050912,TMEM123,transmembrane protein 123,external side of plasma membrane|membrane|integral component of membrane|,oncosis|,molecular_function|,10,0,0,10,-0.6,2.65,-0.4,1.03,-1.03,0.651,0,0,-1.9,0.5
ENSMUSG00000002324,REC8,REC8 meiotic recombination protein,"nuclear chromosome|chromosome, centromeric region|condensed nuclear chromosome kinetochore|condensed nuclear chromosome, centromeric region|condensed nuclear chromosome|synaptonemal complex|lateral element|male germ cell nucleus|nucleus|chromosome|meiotic cohesin complex|nuclear meiotic cohesin complex|",double-strand break repair via homologous recombination|oocyte maturation|chromosome segregation|meiotic nuclear division|synapsis|male meiosis I|spermatid development|fertilization|linear element assembly|seminiferous tubule development|,protein binding|,10,-0.3,1.3,10,0.3,1.4,0.2,1.01,1.01,0.655,0,0,-0.9,2
ENSMUSG00000016529,IL10,interleukin 10,extracellular region|extracellular space|extracellular space|,"negative regulation of cytokine production|response to molecule of bacterial origin|negative regulation of cytokine secretion involved in immune response|negative regulation of chronic inflammatory response to antigenic stimulus|positive regulation of B cell apoptotic process|inflammatory response|immune response|regulation of gene expression|negative regulation of myeloid dendritic cell activation|negative regulation of B cell proliferation|negative regulation of interferon-gamma production|negative regulation of interleukin-12 production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|receptor biosynthetic process|negative regulation of tumor necrosis factor biosynthetic process|defense response to bacterium|negative regulation of apoptotic process|negative regulation of growth of symbiont in host|negative regulation of nitric oxide biosynthetic process|positive regulation of MHC class II biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of cytokine secretion|negative regulation of inflammatory response|negative regulation of inflammatory response|negative regulation of membrane protein ectodomain proteolysis|positive regulation of sequence-specific DNA binding transcription factor activity|response to glucocorticoid|regulation of sensory perception of pain|branching involved in labyrinthine layer morphogenesis|",cytokine activity|cytokine activity|interleukin-10 receptor binding|,10,0.3,1.31,10,-0.6,0.631,0.3,1.01,1.01,0.655,0,0,-1.6,1.3
ENSMUSG00000029547,INTS1,integrator complex subunit 1,nucleus|membrane|membrane|integral component of membrane|integrator complex|,blastocyst growth|inner cell mass cell proliferation|snRNA processing|U2 snRNA 3'-end processing|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|,molecular_function|,9,-1,3.12,9,-0.1,0.15,-0.2,1,-1,0.657,0,0,-2,0.8
ENSMUSG00000025347,METTL7B,methyltransferase like 7B,cellular_component|,biological_process|metabolic process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.2,0.111,10,-0.3,1.66,-0.2,1,-1,0.657,0,0,-1.1,1.8
ENSMUSG00000021947,CRYL1,"crystallin, lambda 1",cytoplasm|extracellular vesicular exosome|,fatty acid metabolic process|oxidation-reduction process|,"3-hydroxyacyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|protein homodimerization activity|L-gulonate 3-dehydrogenase activity|coenzyme binding|NAD+ binding|",10,0.7,1.41,10,-0.3,1.9,0.6,1,1,0.657,0,0,-0.9,1.8
ENSMUSG00000031216,STARD8,START domain containing 8,intracellular|cell junction|,signal transduction|,molecular_function|GTPase activator activity|lipid binding|,10,-0.9,0.629,10,0.3,1.21,0.2,0.993,0.993,0.658,0,0,-1.7,1.5
ENSMUSG00000004951,HSPB1,heat shock protein 1,proteasome complex|extracellular space|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|Z disc|contractile fiber|extracellular vesicular exosome|,negative regulation of protein kinase activity|response to stress|response to unfolded protein|positive regulation of interleukin-1 beta production|intracellular signal transduction|cellular response to vascular endothelial growth factor stimulus|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway|positive regulation of tumor necrosis factor biosynthetic process|regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of blood vessel endothelial cell migration|positive regulation of angiogenesis|negative regulation of protein serine/threonine kinase activity|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|positive regulation of endothelial cell chemotaxis|negative regulation of apoptotic signaling pathway|,protein kinase C binding|protein kinase C inhibitor activity|protein kinase binding|identical protein binding|ubiquitin binding|poly(A) RNA binding|,10,-0.4,1.01,10,0.4,1.81,0.3,0.989,0.989,0.659,0,0,-1.3,1.4
ENSMUSG00000032315,CYP1A1,"cytochrome P450, family 1, subfamily a, polypeptide 1",cytoplasm|mitochondrion|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,porphyrin-containing compound metabolic process|amine metabolic process|toxin metabolic process|response to toxic substance|coumarin metabolic process|flavonoid metabolic process|insecticide metabolic process|drug metabolic process|dibenzo-p-dioxin catabolic process|9-cis-retinoic acid biosynthetic process|heterocycle metabolic process|hydrogen peroxide biosynthetic process|oxidation-reduction process|oxidation-reduction process|demethylation|cellular response to organic cyclic compound|positive regulation of G1/S transition of mitotic cell cycle|,"catalytic activity|monooxygenase activity|monooxygenase activity|iron ion binding|steroid hydroxylase activity|oxidoreductase activity|oxidoreductase activity|oxidoreductase activity, acting on diphenols and related substances as donors|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|flavonoid 3'-monooxygenase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|enzyme binding|heme binding|demethylase activity|metal ion binding|aromatase activity|vitamin D 24-hydroxylase activity|",10,0.3,0.698,10,-0.4,2.16,-0.2,0.979,-0.979,0.66,0,0,-1.6,1.1
ENSMUSG00000000094,TBX4,T-box 4,nucleus|,"angiogenesis|morphogenesis of an epithelium|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|lung development|embryonic limb morphogenesis|limb morphogenesis|limb morphogenesis|limb morphogenesis|skeletal system morphogenesis|skeletal system morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.4,1.66,10,-0.1,0.106,-0.3,0.975,-0.975,0.661,0,0,-1.7,0.9
ENSMUSG00000004637,WWOX,WW domain-containing oxidoreductase,intracellular|nucleus|nucleus|cytoplasm|mitochondrion|Golgi apparatus|cytosol|plasma membrane|microvillus|,osteoblast differentiation|apoptotic process|metabolic process|Wnt signaling pathway|negative regulation of Wnt signaling pathway|positive regulation of transcription from RNA polymerase II promoter|skeletal system morphogenesis|oxidation-reduction process|cellular response to transforming growth factor beta stimulus|cellular response to transforming growth factor beta stimulus|intrinsic apoptotic signaling pathway by p53 class mediator|extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|RNA polymerase II transcription coactivator activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|protein binding|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|enzyme binding|enzyme binding|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.3,0.38,10,0.2,0.751,0.2,0.975,0.975,0.661,0,0,-1,1.6
ENSMUSG00000003549,ERCC1,"excision repair cross-complementing rodent repair deficiency, complementation group 1","nucleotide-excision repair complex|nuclear chromosome, telomeric region|nucleus|transcription factor TFIID complex|cytoplasm|","pyrimidine dimer repair by nucleotide-excision repair|DNA catabolic process, endonucleolytic|replicative cell aging|DNA repair|nucleotide-excision repair|nucleotide-excision repair|nucleotide-excision repair, DNA incision, 3'-to lesion|nucleotide-excision repair, DNA incision, 5'-to lesion|double-strand break repair|DNA recombination|DNA recombination|mitotic recombination|syncytium formation|cellular response to DNA damage stimulus|response to oxidative stress|germ cell development|spermatogenesis|cell proliferation|male gonad development|UV protection|response to X-ray|multicellular organismal aging|negative regulation of telomere maintenance|post-embryonic hemopoiesis|multicellular organism growth|multicellular organism growth|interstrand cross-link repair|isotype switching|cell development|oogenesis|chromosome organization|",single-stranded DNA endodeoxyribonuclease activity|TFIID-class transcription factor binding|DNA binding|damaged DNA binding|single-stranded DNA binding|nuclease activity|endonuclease activity|protein binding|protein C-terminus binding|hydrolase activity|TBP-class protein binding|protein domain specific binding|structure-specific DNA binding|,10,0.2,0.685,10,0.2,0.373,0.2,0.973,0.973,0.662,0,0,-1,1.7
ENSMUSG00000054932,AFP,alpha fetoprotein,extracellular region|extracellular space|extracellular space|cytoplasm|cytoplasm|,ovulation from ovarian follicle|transport|sexual reproduction|progesterone metabolic process|SMAD protein signal transduction|,beta-glucuronidase activity|metal ion binding|,10,0,0,10,0.6,2.89,0.4,0.972,0.972,0.662,0,0,-0.6,1.8
ENSMUSG00000031533,MRPS31,mitochondrial ribosomal protein S31,nucleolus|mitochondrion|mitochondrion|mitochondrial small ribosomal subunit|ribosome|ribonucleoprotein complex|,biological_process|,structural constituent of ribosome|protein domain specific binding|poly(A) RNA binding|,10,0.1,0.0275,9,0.3,1.07,0.3,0.97,0.97,0.662,0,0,-1.3,1.6
ENSMUSG00000028967,ERRFI1,ERBB receptor feedback inhibitor 1,nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|membrane|extrinsic component of cytoplasmic side of plasma membrane|,negative regulation of epidermal growth factor-activated receptor activity|negative regulation of epidermal growth factor-activated receptor activity|stress-activated protein kinase signaling cascade|negative regulation of protein autophosphorylation|negative regulation of epidermal growth factor receptor signaling pathway|skin morphogenesis|regulation of keratinocyte differentiation|lung alveolus development|negative regulation of peptidyl-tyrosine phosphorylation|lung vasculature development|lung epithelium development|,protein binding|kinase binding|protein kinase binding|,10,0.4,1.35,10,0,0,0.4,0.957,0.957,0.664,0,0,-0.7,1.8
ENSMUSG00000046240,HEPACAM,hepatocyte cell adhesion molecule,cytoplasm|cell-cell junction|membrane|integral component of membrane|axon|,cell cycle|cell cycle arrest|cell adhesion|cellular protein localization|regulation of growth|,protein binding|,10,-0.3,0.47,10,-0.3,0.565,-0.3,0.95,-0.95,0.666,0,0,-1.6,1.1
ENSMUSG00000021774,UBE2E1,ubiquitin-conjugating enzyme E2E 1,ubiquitin ligase complex|nucleus|,protein polyubiquitination|histone monoubiquitination|protein ubiquitination|protein ubiquitination|ISG15-protein conjugation|histone H2B ubiquitination|protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|ISG15 ligase activity|,10,0.2,0.367,10,0.2,0.653,0.2,0.937,0.937,0.668,0,0,-1.3,1.5
ENSMUSG00000015305,SASH1,SAM and SH3 domain containing 1,membrane|protein complex|,protein polyubiquitination|positive regulation of endothelial cell migration|positive regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of JUN kinase activity|positive regulation of angiogenesis|regulation of protein K63-linked ubiquitination|positive regulation of p38MAPK cascade|positive regulation of NIK/NF-kappaB signaling|regulation of protein autoubiquitination|,protein C-terminus binding|protein kinase binding|mitogen-activated protein kinase kinase kinase binding|protein complex scaffold|,9,-0.3,1.14,9,-0.1,0.0562,-0.3,0.934,-0.934,0.668,0,0,-1.6,1.3
ENSMUSG00000038482,TFDP1,transcription factor Dp 1,nucleus|transcription factor complex|,"mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|epidermis development|anoikis|positive regulation of transcription, DNA-templated|regulation of DNA biosynthetic process|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|transcription factor binding|protein domain specific binding|,6,0.3,0.218,6,-0.9,1.57,0.3,0.931,0.931,0.669,0,0,-2,1.3
ENSMUSG00000030337,VAMP1,vesicle-associated membrane protein 1,mitochondrion|cell surface|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|neuron projection|synapse|,vesicle-mediated transport|SNARE complex assembly|,None,10,0.5,2.08,10,0,0,0.2,0.93,0.93,0.669,0,0,-0.7,1.8
ENSMUSG00000006724,CYP27B1,"cytochrome P450, family 27, subfamily b, polypeptide 1",cytoplasm|mitochondrion|mitochondrion|membrane|,calcium ion transport|aging|negative regulation of cell proliferation|negative regulation of calcidiol 1-monooxygenase activity|positive regulation of vitamin D 24-hydroxylase activity|negative regulation of cell growth|regulation of bone mineralization|response to lipopolysaccharide|response to insulin|response to vitamin D|response to vitamin D|response to interferon-gamma|response to prostaglandin E|calcitriol biosynthetic process from calciol|calcitriol biosynthetic process from calciol|vitamin D metabolic process|vitamin D catabolic process|vitamin D catabolic process|response to drug|positive regulation of keratinocyte differentiation|response to copper ion|response to cAMP|calcium ion homeostasis|oxidation-reduction process|G1 to G0 transition|positive regulation of vitamin D receptor signaling pathway|,"monooxygenase activity|calcidiol 1-monooxygenase activity|calcidiol 1-monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|",10,-0.3,0.97,10,-0.7,0.53,-0.4,0.924,-0.924,0.67,0,0,-1.9,0.7
ENSMUSG00000030745,IL21R,interleukin 21 receptor,membrane|integral component of membrane|,cytokine-mediated signaling pathway|,transmembrane signaling receptor activity|cytokine receptor activity|cytokine receptor activity|,10,-0.7,1.41,10,-0.1,0.09,-0.3,0.922,-0.922,0.671,0,0,-1.9,0.8
ENSMUSG00000073565,PRR16,proline rich 16,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.284,10,0.3,2.3,0.3,0.915,0.915,0.672,0,0,-1.4,1.4
ENSMUSG00000034724,CNOT6L,"CCR4-NOT transcription complex, subunit 6-like",nucleus|cytoplasm|cytoplasm|CCR4-NOT complex|,"nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|regulation of translation|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cytoplasmic mRNA processing body assembly|gene silencing by RNA|mRNA destabilization|RNA phosphodiester bond hydrolysis, exonucleolytic|",nuclease activity|exonuclease activity|poly(A)-specific ribonuclease activity|protein binding|hydrolase activity|metal ion binding|,9,-0.4,1.25,9,-0.1,0.191,-0.2,0.913,-0.913,0.672,0,0,-1.8,0.8
ENSMUSG00000025235,BBS4,Bardet-Biedl syndrome 4 (human),pericentriolar material|nucleus|cytoplasm|centrosome|centrosome|centriole|cytoskeleton|plasma membrane|cilium|membrane|nonmotile primary cilium|motile cilium|motile cilium|centriolar satellite|centriolar satellite|BBSome|BBSome|ciliary basal body|cell projection|ciliary membrane|,microtubule cytoskeleton organization|mitotic cytokinesis|neural tube closure|retina homeostasis|negative regulation of systemic arterial blood pressure|transport|spermatid development|sensory perception of smell|protein localization|metabolic process|negative regulation of gene expression|protein transport|dendrite development|regulation of lipid metabolic process|striatum development|hippocampus development|cerebral cortex development|cell projection organization|adult behavior|regulation of cytokinesis|leptin-mediated signaling pathway|protein localization to organelle|microtubule anchoring at centrosome|nonmotile primary cilium assembly|negative regulation of appetite by leptin-mediated signaling pathway|positive regulation of multicellular organism growth|cilium assembly|response to leptin|photoreceptor cell maintenance|positive regulation of cilium assembly|retinal rod cell development|brain morphogenesis|centrosome organization|maintenance of protein location in nucleus|cilium morphogenesis|regulation of cilium beat frequency involved in ciliary motility|protein localization to centrosome|,RNA polymerase II repressing transcription factor binding|microtubule motor activity|protein binding|dynactin binding|alpha-tubulin binding|beta-tubulin binding|,10,-0.1,0.571,10,-0.2,0.443,-0.2,0.911,-0.911,0.673,0,0,-1.6,1.2
ENSMUSG00000036206,SH3BP4,SH3-domain binding protein 4,nucleus|cytoplasm|coated pit|membrane|cytoplasmic vesicle|extracellular vesicular exosome|,endocytosis|negative regulation of cell proliferation|positive regulation of autophagy|negative regulation of cell growth|negative regulation of TOR signaling|negative regulation of GTPase activity|regulation of catalytic activity|protein localization to lysosome|cellular response to amino acid stimulus|,GDP-dissociation inhibitor activity|Ras GTPase binding|identical protein binding|,10,0,0,10,2.1,3.06,0.1,0.903,0.903,0.674,0,0,-0.4,3.9
ENSMUSG00000029661,COL1A2,"collagen, type I, alpha 2",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type I trimer|collagen type I trimer|extracellular space|intracellular|extracellular matrix|extracellular vesicular exosome|,skeletal system development|blood vessel development|transforming growth factor beta receptor signaling pathway|Rho protein signal transduction|regulation of blood pressure|collagen fibril organization|skin morphogenesis|protein heterotrimerization|cellular response to amino acid stimulus|,"extracellular matrix structural constituent|protein binding|protein binding, bridging|identical protein binding|SMAD binding|metal ion binding|platelet-derived growth factor binding|",10,0.3,1.28,10,0.1,0.041,0.2,0.898,0.898,0.675,0,0,-0.8,1.8
ENSMUSG00000000402,EGFL6,"EGF-like-domain, multiple 6",extracellular region|proteinaceous extracellular matrix|basement membrane|membrane|extracellular matrix|,cell adhesion|multicellular organismal development|positive regulation of cell-substrate adhesion|cell differentiation|extracellular matrix organization|,calcium ion binding|,10,-0.2,1.43,10,0.3,1.95,0.2,0.898,0.898,0.675,0,0,-1.3,1.5
ENSMUSG00000026504,SDCCAG8,serologically defined colon cancer antigen 8,cytoplasm|centrosome|centrosome|centriole|cytoskeleton|cell-cell junction|cell junction|,establishment of cell polarity|tube formation|,molecular_function|,10,-0.2,0.996,10,-0.7,0.266,-0.3,0.895,-0.895,0.676,0,0,-1.9,0.8
ENSMUSG00000000266,MID2,midline 2,intracellular|cytoplasm|cytoskeleton|microtubule|microtubule|extracellular vesicular exosome|,negative regulation of viral transcription|protein localization to microtubule|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|negative regulation of viral entry into host cell|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|negative regulation of viral release from host cell|,"microtubule binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein heterodimerization activity|phosphoprotein binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.2,1.37,0.2,0.888,0.888,0.677,0,0,-0.7,1.9
ENSMUSG00000032997,CHPF,chondroitin polymerizing factor,cellular_component|cytoplasm|mitochondrion|Golgi apparatus|membrane|integral component of membrane|Golgi cisterna membrane|,chondroitin sulfate biosynthetic process|chondroitin sulfate biosynthetic process|,"protein binding|acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity|",10,0.3,0.81,10,0.5,0.423,0.4,0.887,0.887,0.677,0,0,-0.7,1.8
ENSMUSG00000029275,GFI1,growth factor independent 1,nucleus|nuclear matrix|nuclear body|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|mechanosensory behavior|negative regulation of cell fate specification|negative regulation of calcidiol 1-monooxygenase activity|negative regulation of neuron projection development|negative regulation of NF-kappaB transcription factor activity|regulation of toll-like receptor signaling pathway|inner ear morphogenesis|auditory receptor cell differentiation|positive regulation of cell fate specification|cell fate commitment|negative regulation of transcription, DNA-templated|positive regulation of interleukin-6-mediated signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|protein binding|zinc ion binding|transcription regulatory region DNA binding|metal ion binding|,10,0.8,2.57,10,0.1,0.122,0.4,0.885,0.885,0.678,0,0,-0.4,2
ENSMUSG00000030963,UMOD,uromodulin,spindle pole|extracellular region|extracellular space|Golgi apparatus|plasma membrane|membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|apical plasma membrane|anchored component of membrane|cytoplasmic vesicle|cell projection|membrane raft|apical part of cell|extracellular vesicular exosome|primary cilium|,heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|excretion|chemical homeostasis|neutrophil migration|regulation of ion homeostasis|,calcium ion binding|IgG binding|,10,-0.2,1.93,10,0,0,-0.2,0.884,-0.884,0.678,0,0,-1.6,1.2
ENSMUSG00000030541,IDH2,"isocitrate dehydrogenase 2 (NADP+), mitochondrial",mitochondrion|mitochondrion|mitochondrial inner membrane|,glyoxylate cycle|tricarboxylic acid cycle|isocitrate metabolic process|response to stress|oxidation-reduction process|,"magnesium ion binding|isocitrate dehydrogenase (NADP+) activity|isocitrate dehydrogenase (NADP+) activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|metal ion binding|NAD binding|",10,0.2,0.787,10,0.2,0.173,0.2,0.884,0.884,0.678,0,0,-1.7,1.3
ENSMUSG00000027715,CCNA2,cyclin A2,female pronucleus|male pronucleus|nucleus|nucleus|cytoplasm|cytoplasm|,"regulation of cyclin-dependent protein serine/threonine kinase activity|cell cycle|mitotic nuclear division|regulation of G2/M transition of mitotic cell cycle|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of fibroblast proliferation|cell division|regulation of cell cycle|",protein binding|protein kinase binding|,10,0.6,2.72,10,-0.1,0.106,0.5,0.884,0.884,0.678,0,0,-1.4,1.6
ENSMUSG00000038860,GARNL3,GTPase activating RANGAP domain-like 3,cellular_component|,biological_process|regulation of small GTPase mediated signal transduction|,molecular_function|small GTPase regulator activity|GTPase activator activity|,10,-0.3,1.21,10,0,0,-0.4,0.877,-0.877,0.679,0,0,-1.9,0.6
ENSMUSG00000036223,SKA1,spindle and kinetochore associated complex subunit 1,"chromosome, centromeric region|kinetochore|condensed chromosome outer kinetochore|chromosome|cytoplasm|cytoskeleton|microtubule|spindle microtubule|microtubule cytoskeleton|",cell cycle|chromosome segregation|mitotic nuclear division|regulation of microtubule polymerization or depolymerization|cell division|,microtubule binding|,10,0.8,1.71,10,-0.7,2.39,0.3,0.877,0.877,0.679,0,0,-1.6,1.6
ENSMUSG00000042351,GRAP2,GRB2-related adaptor protein 2,nucleus|cytoplasm|endosome|,None,protein binding|,10,0,0,10,0.6,1.21,0.3,0.876,0.876,0.679,0,0,-0.8,1.9
ENSMUSG00000017146,BRCA1,breast cancer 1,condensed chromosome|condensed nuclear chromosome|ruffle|nucleus|chromosome|cytoplasm|cytoplasm|mitochondrial matrix|centrosome|plasma membrane|focal adhesion|ribonucleoprotein complex|BRCA1-BARD1 complex|filamentous actin|protein complex|BRCA1-A complex|,"double-strand break repair via homologous recombination|DNA replication|DNA repair|postreplication repair|double-strand break repair|DNA recombination|regulation of gene expression by genetic imprinting|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|cellular response to DNA damage stimulus|cell cycle|chromosome segregation|centrosome cycle|intrinsic apoptotic signaling pathway in response to DNA damage|dosage compensation by inactivation of X chromosome|response to ionizing radiation|protein ubiquitination|positive regulation of protein ubiquitination|G2 DNA damage checkpoint|substrate adhesion-dependent cell spreading|positive regulation of histone acetylation|positive regulation of histone acetylation|negative regulation of histone acetylation|chordate embryonic development|response to estrogen|regulation of DNA methylation|negative regulation of fatty acid biosynthetic process|positive regulation of DNA repair|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|centrosome duplication|positive regulation of histone H3-K4 methylation|positive regulation of histone H3-K4 methylation|negative regulation of histone H3-K4 methylation|negative regulation of histone H3-K9 methylation|negative regulation of histone H3-K9 methylation|positive regulation of histone H3-K9 methylation|protein autoubiquitination|positive regulation of histone H4-K20 methylation|positive regulation of histone H4-K20 methylation|positive regulation of cell cycle arrest|cellular response to indole-3-methanol|protein K6-linked ubiquitination|regulation of cell motility|positive regulation of histone H3-K9 acetylation|positive regulation of histone H3-K9 acetylation|positive regulation of histone H4-K16 acetylation|positive regulation of histone H4-K16 acetylation|","DNA binding|damaged DNA binding|RNA binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|enzyme binding|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,1.5,1.62,10,-0.2,0.329,-0.3,0.871,-0.871,0.68,0,0,-0.9,2.9
ENSMUSG00000024778,FAS,Fas (TNF receptor superfamily member 6),extracellular region|extracellular space|nucleus|cytoplasm|plasma membrane|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|apical plasma membrane|secretory granule|death-inducing signaling complex|CD95 death-inducing signaling complex|CD95 death-inducing signaling complex|sarcolemma|neuron projection|neuronal cell body|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|apical dendrite|,immunoglobulin production|renal system process|apoptotic process|apoptotic process|activation-induced cell death of T cells|activation-induced cell death of T cells|inflammatory cell apoptotic process|inflammatory cell apoptotic process|transformed cell apoptotic process|immune response|signal transduction|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|response to toxic substance|gene expression|regulation of gene expression|positive regulation of cell death|B cell mediated immunity|dendrite regeneration|positive regulation of protein homooligomerization|tumor necrosis factor-mediated signaling pathway|regulation of cell proliferation|regulation of apoptotic process|T cell homeostasis|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative thymic T cell selection|regulation of lymphocyte differentiation|regulation of myeloid cell differentiation|spleen development|negative regulation of B cell activation|protein homooligomerization|response to glucocorticoid|neuron apoptotic process|cellular response to lithium ion|cellular response to hyperoxia|positive regulation of release of cytochrome c from mitochondria|motor neuron apoptotic process|apoptotic signaling pathway|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|hepatocyte apoptotic process|necroptotic signaling pathway|necroptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,protease binding|transmembrane signaling receptor activity|tumor necrosis factor-activated receptor activity|protein binding|kinase binding|protein complex binding|identical protein binding|,10,0.1,0.154,10,0.2,0.942,0.2,0.863,0.863,0.682,0,0,-0.8,1.8
ENSMUSG00000030530,FURIN,furin (paired basic amino acid cleaving enzyme),extracellular space|early endosome|endoplasmic reticulum membrane|Golgi apparatus|trans-Golgi network|plasma membrane|cell surface|trans-Golgi network transport vesicle membrane|membrane|membrane|integral component of membrane|trans-Golgi network transport vesicle|Golgi cisterna|membrane raft|extracellular vesicular exosome|,signal peptide processing|proteolysis|cell proliferation|regulation of signal transduction|negative regulation of endopeptidase activity|protein processing|protein processing|peptide hormone processing|positive regulation of cell migration|positive regulation of transforming growth factor beta receptor signaling pathway|negative regulation of low-density lipoprotein particle receptor catabolic process|nerve growth factor production|negative regulation of transforming growth factor beta1 production|secretion by cell|regulation of protein catabolic process|peptide biosynthetic process|regulation of endopeptidase activity|,protease binding|endopeptidase activity|serine-type endopeptidase activity|serine-type endopeptidase activity|serine-type endopeptidase inhibitor activity|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|peptide binding|metal ion binding|nerve growth factor binding|,10,0,0,10,0.3,1.23,0.3,0.861,0.861,0.683,0,0,-0.6,1.9
ENSMUSG00000051355,COMMD1,COMM domain containing 1,nucleus|cytoplasm|Cul2-RING ubiquitin ligase complex|extracellular vesicular exosome|,cellular copper ion homeostasis|positive regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|regulation of proteasomal ubiquitin-dependent protein catabolic process|copper ion homeostasis|,copper ion binding|sodium channel inhibitor activity|identical protein binding|protein homodimerization activity|metal ion binding|,5,-0.6,2.3,5,0,0,-0.3,0.861,-0.861,0.683,0,0,-2,1.1
ENSMUSG00000053641,DENND4A,DENN/MADD domain containing 4A,cellular_component|,positive regulation of Rab GTPase activity|,Rab guanyl-nucleotide exchange factor activity|,10,-0.5,2.82,10,0,0,-0.3,0.86,-0.86,0.683,0,0,-1.6,1.3
ENSMUSG00000098789,JMJD7,jumonji domain containing 7,cellular_component|,biological_process|,molecular_function|,1,-0.4,1.22,1,0,0,-0.4,0.856,-0.856,0.683,0,0,-2,1.7
ENSMUSG00000021125,ARG2,arginase type II,mitochondrion|mitochondrion|,urea cycle|arginine metabolic process|striated muscle contraction|regulation of L-arginine import|arginine catabolic process to ornithine|negative regulation of striated muscle contraction|negative regulation of nitric-oxide synthase activity|,"arginase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines|metal ion binding|nitric-oxide synthase binding|",10,0.8,1.48,10,-0.5,0.779,0.4,0.855,0.855,0.684,0,0,-1.4,1.7
ENSMUSG00000022089,BIN3,bridging integrator 3,cytoplasm|cytoskeleton|actin filament|,barrier septum assembly|cell cycle|protein localization|unidimensional cell growth|regulation of lamellipodium assembly|myoblast migration involved in skeletal muscle regeneration|skeletal muscle tissue regeneration|skeletal muscle fiber development|cell division|,molecular_function|,9,0.3,1.85,10,0,0,0.2,0.849,0.849,0.685,0,0,-0.9,1.8
ENSMUSG00000043535,SETX,senataxin,nucleus|nucleoplasm|cytoplasm|,DNA repair|double-strand break repair|termination of RNA polymerase II transcription|cellular response to DNA damage stimulus|circadian rhythm|rhythmic process|,nucleotide binding|helicase activity|protein binding|ATP binding|hydrolase activity|,10,0,0,10,0.9,3.59,0.9,0.847,0.847,0.685,0,0,-0.5,2
ENSMUSG00000033122,HSD17B3,hydroxysteroid (17-beta) dehydrogenase 3,intracellular membrane-bounded organelle|,lipid metabolic process|steroid biosynthetic process|metabolic process|oxidation-reduction process|,estradiol 17-beta-dehydrogenase activity|oxidoreductase activity|testosterone dehydrogenase (NAD+) activity|testosterone 17-beta-dehydrogenase (NADP+) activity|,10,1,1.94,10,0.2,0.368,0.1,0.847,0.847,0.685,0,0,-0.4,2
ENSMUSG00000031980,AGT,"angiotensinogen (serpin peptidase inhibitor, clade A, member 8)",extracellular space|extracellular space|cytoplasm|extracellular vesicular exosome|blood microparticle|,"ovarian follicle rupture|blood vessel development|branching involved in ureteric bud morphogenesis|kidney development|kidney development|regulation of systemic arterial blood pressure by circulatory renin-angiotensin|angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure|renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure|renin-angiotensin regulation of aldosterone production|renin-angiotensin regulation of aldosterone production|regulation of renal output by angiotensin|brain renin-angiotensin system|renal system process|angiotensin-mediated drinking behavior|positive regulation of extracellular matrix constituent secretion|cellular sodium ion homeostasis|cell-matrix adhesion|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|activation of phospholipase C activity|activation of NF-kappaB-inducing kinase activity|excretion|establishment of blood-nerve barrier|regulation of blood pressure|positive regulation of cell proliferation|negative regulation of cell proliferation|response to cold|response to salt stress|regulation of gene expression|positive regulation of activation of JAK2 kinase activity|positive regulation of endothelial cell migration|positive regulation of cardiac muscle hypertrophy|positive regulation of gene expression|positive regulation of cholesterol esterification|negative regulation of endopeptidase activity|regulation of norepinephrine secretion|positive regulation of phosphatidylinositol 3-kinase signaling|artery smooth muscle contraction|response to muscle activity involved in regulation of muscle adaptation|negative regulation of angiogenesis|regulation of proteolysis|extracellular matrix organization|negative regulation of cell growth|peristalsis|positive regulation of cellular protein metabolic process|positive regulation of superoxide anion generation|negative regulation of tissue remodeling|catenin import into nucleus|regulation of renal sodium excretion|positive regulation of renal sodium excretion|positive regulation of multicellular organism growth|vasoconstriction|vasodilation|hormone metabolic process|drinking behavior|regulation of apoptotic process|positive regulation of catalytic activity|positive regulation of MAPK cascade|negative regulation of neuron apoptotic process|positive regulation of nitric oxide biosynthetic process|positive regulation of fatty acid biosynthetic process|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of blood pressure|positive regulation of transcription, DNA-templated|positive regulation of vasodilation|positive regulation of organ growth|positive regulation of organ growth|astrocyte activation|fibroblast proliferation|positive regulation of fibroblast proliferation|regulation of long-term neuronal synaptic plasticity|smooth muscle cell proliferation|smooth muscle cell proliferation|smooth muscle cell proliferation|cytokine secretion|regulation of inflammatory response|regulation of inflammatory response|positive regulation of peptidyl-tyrosine phosphorylation|smooth muscle cell differentiation|smooth muscle cell differentiation|negative regulation of neurotrophin TRK receptor signaling pathway|stress-activated MAPK cascade|regulation of calcium ion transport|regulation of transmission of nerve impulse|cell growth involved in cardiac muscle cell development|positive regulation of protein tyrosine kinase activity|ERK1 and ERK2 cascade|uterine smooth muscle contraction|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of extrinsic apoptotic signaling pathway|",serine-type endopeptidase inhibitor activity|hormone activity|angiotensin receptor binding|type 1 angiotensin receptor binding|type 1 angiotensin receptor binding|type 2 angiotensin receptor binding|type 2 angiotensin receptor binding|,10,-0.1,0.0677,10,-0.5,2.09,-0.2,0.846,-0.846,0.685,0,0,-1.7,1.3
ENSMUSG00000035121,NEIL2,nei like 2 (E. coli),nucleus|cytoplasm|spindle microtubule|microtubule cytoskeleton|,DNA repair|base-excision repair|nucleotide-excision repair|cellular response to DNA damage stimulus|metabolic process|,"purine-specific mismatch base pair DNA N-glycosylase activity|nucleic acid binding|DNA binding|damaged DNA binding|catalytic activity|DNA-(apurinic or apyrimidinic site) lyase activity|uracil DNA N-glycosylase activity|microtubule binding|zinc ion binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hydrolase activity, hydrolyzing N-glycosyl compounds|lyase activity|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA-3-methylbase glycosylase activity|metal ion binding|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0.5,2.53,10,-0.5,0.594,0.3,0.84,0.84,0.687,0,0,-1.3,1.6
ENSMUSG00000032323,CYP11A1,"cytochrome P450, family 11, subfamily a, polypeptide 1",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|mitochondrial crista|perikaryon|,lipid metabolic process|steroid biosynthetic process|C21-steroid hormone biosynthetic process|C21-steroid hormone biosynthetic process|mating behavior|steroid metabolic process|cholesterol metabolic process|response to hydrogen peroxide|oxidation-reduction process|,"monooxygenase activity|iron ion binding|cholesterol monooxygenase (side-chain-cleaving) activity|cholesterol monooxygenase (side-chain-cleaving) activity|cholesterol binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|",9,0,0,9,0.3,1.16,0.3,0.837,0.837,0.687,0,0,-0.7,1.9
ENSMUSG00000031714,GAB1,growth factor receptor bound protein 2-associated protein 1,cytoplasm|,activation of MAPK activity|response to oxidative stress|signal transduction|epidermal growth factor receptor signaling pathway|activation of JUN kinase activity|heart development|epidermis development|regulation of cell migration|positive regulation of MAPK cascade|platelet-derived growth factor receptor signaling pathway|labyrinthine layer development|interleukin-6-mediated signaling pathway|,signal transducer activity|protein binding|,10,0.1,0.000236,10,-0.2,1.13,-0.2,0.836,-0.836,0.687,0,0,-1.5,1.2
ENSMUSG00000050295,FOXC1,forkhead box C1,nucleus|nuclear heterochromatin|cytoplasm|,"skeletal system development|ossification|ovarian follicle development|blood vessel development|eye development|eye development|ureteric bud development|in utero embryonic development|somitogenesis|kidney development|lymph vessel development|blood vessel remodeling|heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|Notch signaling pathway|brain development|heart development|heart development|heart development|germ cell migration|neural crest cell development|collagen fibril organization|glycosaminoglycan metabolic process|lacrimal gland development|embryonic heart tube development|odontogenesis of dentin-containing tooth|camera-type eye development|positive regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of organ growth|vascular endothelial growth factor receptor signaling pathway|paraxial mesoderm formation|mesenchymal cell differentiation|artery morphogenesis|regulation of blood vessel size|ventricular cardiac muscle tissue morphogenesis|cardiac muscle cell proliferation|negative regulation of apoptotic process involved in outflow tract morphogenesis|","RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription factor binding|DNA binding, bending|sequence-specific DNA binding|transcription regulatory region DNA binding|",10,0.2,0.25,10,0.3,0.71,0.2,0.836,0.836,0.687,0,0,-0.7,1.9
ENSMUSG00000046643,OLFR218,olfactory receptor 218,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.16,10,0,0,-0.4,0.832,-0.832,0.688,0,0,-1.9,0.5
ENSMUSG00000017639,RAB11FIP4,RAB11 family interacting protein 4 (class II),extracellular space|endosome|membrane|endocytic vesicle|midbody|cytoplasmic vesicle|cleavage furrow|recycling endosome membrane|,cytokinesis|transport|cell cycle|cell division|,calcium ion binding|Rab GTPase binding|ADP-ribosylation factor binding|protein homodimerization activity|metal ion binding|,10,-0.2,0.619,10,1.9,3.69,1.8,0.83,0.83,0.688,0,0,-0.5,3
ENSMUSG00000013523,BCAS1,breast carcinoma amplified sequence 1,cytoplasm|cytosol|postsynaptic density|,biological_process|,protein homodimerization activity|,10,0,0,10,-0.4,1.56,-0.2,0.83,-0.83,0.688,0,0,-1.7,1
ENSMUSG00000025742,PRPS2,phosphoribosyl pyrophosphate synthetase 2,ribose phosphate diphosphokinase complex|protein complex|extracellular vesicular exosome|,5-phosphoribose 1-diphosphate biosynthetic process|AMP biosynthetic process|ribonucleoside monophosphate biosynthetic process|nucleotide biosynthetic process|phosphorylation|ribose phosphate metabolic process|cellular biosynthetic process|,nucleotide binding|magnesium ion binding|ribose phosphate diphosphokinase activity|ATP binding|AMP binding|kinase activity|transferase activity|GDP binding|carbohydrate binding|ADP binding|metal ion binding|,10,1.1,3.67,10,-0.2,0.623,0.2,0.829,0.829,0.689,0,0,-0.8,2
ENSMUSG00000043670,DIRAS1,"DIRAS family, GTP-binding RAS-like 1",plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|,nucleotide binding|GTPase activity|GTP binding|,10,0.4,1.07,9,0,0,0.4,0.828,0.828,0.689,0,0,-0.6,1.9
ENSMUSG00000018509,CENPV,centromere protein V,"chromosome, centromeric region|kinetochore|kinetochore|nucleus|nucleus|chromosome|cytoplasm|cytoskeleton|microtubule cytoskeleton|spindle midzone|spindle midzone|",ameboidal cell migration|cell cycle|mitotic nuclear division|metabolic process|centromeric heterochromatin assembly|centromeric heterochromatin assembly|positive regulation of cytokinesis|positive regulation of cytokinesis|regulation of chromosome organization|regulation of chromosome organization|centromere complex assembly|centromere complex assembly|cell division|,molecular_function|carbon-sulfur lyase activity|,10,0.3,0.276,10,0.2,0.695,0.2,0.82,0.82,0.69,0,0,-0.9,1.8
ENSMUSG00000055128,CGRRF1,cell growth regulator with ring finger domain 1,nucleus|intracellular membrane-bounded organelle|,cell cycle|cell cycle arrest|negative regulation of cell growth|,molecular_function|zinc ion binding|metal ion binding|,10,0.4,1.24,10,0.1,0.184,0.2,0.818,0.818,0.691,0,0,-1.5,1.5
ENSMUSG00000020799,TEKT1,tektin 1,nucleus|microtubule|microtubule cytoskeleton|,None,None,10,0.2,0.741,10,0.4,0.486,0.2,0.815,0.815,0.691,0,0,-0.9,1.7
ENSMUSG00000024905,MTL5,"metallothionein-like 5, testis-specific (tesmin)",nucleus|cytoplasm|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,-0.3,1.44,10,0.4,0.7,0.2,0.81,0.81,0.692,0,0,-1.2,1.5
ENSMUSG00000039653,BAAT,bile acid-Coenzyme A: amino acid N-acyltransferase,cytoplasm|peroxisome|cytosol|cytosol|,bile acid conjugation|glycine metabolic process|lipid metabolic process|fatty acid metabolic process|acyl-CoA metabolic process|bile acid biosynthetic process|bile acid metabolic process|taurine metabolic process|,"receptor binding|palmitoyl-CoA hydrolase activity|N-acyltransferase activity|N-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|hydrolase activity|thiolester hydrolase activity|glycine N-choloyltransferase activity|medium-chain acyl-CoA hydrolase activity|long-chain acyl-CoA hydrolase activity|very long chain acyl-CoA hydrolase activity|",10,0.1,0.0386,10,0.4,1.32,0.2,0.803,0.803,0.693,0,0,-0.8,1.8
ENSMUSG00000071317,BVES,blood vessel epicardial substance,plasma membrane|tight junction|tight junction|membrane|integral component of membrane|integral component of membrane|lateral plasma membrane|lateral plasma membrane|cell junction|,positive regulation of receptor recycling|regulation of heart rate|hematopoietic progenitor cell differentiation|cell adhesion|multicellular organismal development|regulation of cell shape|vesicle-mediated transport|regulation of Rac GTPase activity|substrate adhesion-dependent cell spreading|positive regulation of locomotion|regulation of membrane potential|regulation of Cdc42 GTPase activity|sinoatrial node cell development|epithelial cell-cell adhesion|,structural molecule activity|protein binding|cAMP binding|,9,-0.1,0.572,10,-0.2,0.389,-0.1,0.802,-0.802,0.693,0,0,-1.8,0.9
ENSMUSG00000062580,TIMM17A,translocase of inner mitochondrial membrane 17a,mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane presequence translocase complex|membrane|integral component of membrane|integral component of mitochondrial inner membrane|,transport|intracellular protein transport|protein transport|,P-P-bond-hydrolysis-driven protein transmembrane transporter activity|enzyme binding|,6,1.3,3.83,8,-0.5,0.428,1.3,0.798,0.798,0.694,0,0,-1.1,3
ENSMUSG00000026750,PSMB7,"proteasome (prosome, macropain) subunit, beta type 7",proteasome complex|nucleus|cytoplasm|proteasome core complex|microtubule cytoskeleton|extracellular vesicular exosome|,proteolysis|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,5,0.5,0.852,6,0.2,0.555,0.3,0.798,0.798,0.694,0,0,-1.1,2
ENSMUSG00000021708,RASGRF2,RAS protein-specific guanine nucleotide-releasing factor 2,intracellular|cytoplasm|endoplasmic reticulum|plasma membrane|membrane|,small GTPase mediated signal transduction|regulation of Rho protein signal transduction|regulation of small GTPase mediated signal transduction|regulation of N-methyl-D-aspartate selective glutamate receptor activity|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|calmodulin binding|,10,-0.2,0.287,10,0.4,1.22,0.3,0.798,0.798,0.694,0,0,-1,1.6
ENSMUSG00000032598,NCKIPSD,NCK interacting protein with SH3 domain,nucleus|COP9 signalosome|,None,SH3 domain binding|,10,1.2,3.57,10,0,0,0.2,0.797,0.797,0.694,0,0,-0.3,2
ENSMUSG00000008398,ELK3,"ELK3, member of ETS oncogene family",nucleus|nucleus|mitochondrion|intracellular membrane-bounded organelle|,"angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|wound healing|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|purine-rich negative regulatory element binding|sequence-specific DNA binding|,10,-0.3,0.998,10,-0.1,0.0916,-0.2,0.796,-0.796,0.695,0,0,-1.6,1.1
ENSMUSG00000039850,ENDOV,endonuclease V,nucleus|nucleolus|cytoplasm|,"DNA catabolic process, endonucleolytic|DNA repair|RNA phosphodiester bond hydrolysis, endonucleolytic|","magnesium ion binding|DNA binding|RNA binding|single-stranded RNA binding|nuclease activity|endonuclease activity|bidentate ribonuclease III activity|hydrolase activity|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|endoribonuclease activity, producing 5'-phosphomonoesters|structure-specific DNA binding|metal ion binding|",10,0.4,1.08,10,-0.3,0.434,0.3,0.792,0.792,0.695,0,0,-0.9,1.9
ENSMUSG00000025083,AFAP1L2,actin filament associated protein 1-like 2,cytoplasm|,"inflammatory response|regulation of mitotic cell cycle|regulation of interleukin-6 production|positive regulation of interleukin-8 production|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of protein tyrosine kinase activity|",SH3 domain binding|protein tyrosine kinase activator activity|SH2 domain binding|,10,-0.4,1.56,10,0,0,-0.3,0.791,-0.791,0.696,0,0,-1.8,0.7
ENSMUSG00000029394,CDK2AP1,CDK2 (cyclin-dependent kinase 2)-associated protein 1,None,in utero embryonic development|face morphogenesis|,None,10,-0.1,0.0392,10,-0.5,2.11,-0.3,0.788,-0.788,0.696,0,0,-1.9,0.6
ENSMUSG00000023800,TIAM2,T cell lymphoma invasion and metastasis 2,cytoplasm|membrane|cell projection|extracellular vesicular exosome|,signal transduction|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of GTPase activity|,receptor signaling protein activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|,10,-0.1,0.37,10,-0.5,0.926,-0.3,0.785,-0.785,0.697,0,0,-1.9,0.6
ENSMUSG00000000489,PDGFB,"platelet derived growth factor, B polypeptide",extracellular region|extracellular space|cytoplasm|cell surface|membrane|basolateral plasma membrane|,"embryonic placenta development|positive regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|monocyte chemotaxis|positive regulation of glomerular filtration|protein phosphorylation|substrate-dependent cell migration|multicellular organismal development|heart development|blood coagulation|positive regulation of cell proliferation|response to wounding|negative regulation of phosphatidylinositol biosynthetic process|negative regulation of platelet activation|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of smooth muscle cell migration|positive regulation of smooth muscle cell migration|peptidyl-serine phosphorylation|peptidyl-tyrosine phosphorylation|cell projection assembly|actin cytoskeleton organization|actin cytoskeleton organization|positive regulation of cell migration|positive regulation of cell migration|negative regulation of cell migration|positive regulation of protein autophosphorylation|positive regulation of protein autophosphorylation|activation of protein kinase activity|activation of protein kinase B activity|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway|paracrine signaling|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway|positive regulation of MAP kinase activity|positive regulation of MAP kinase activity|positive regulation of MAPK cascade|positive regulation of blood vessel endothelial cell migration|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of DNA replication|positive regulation of fibroblast growth factor receptor signaling pathway|positive regulation of mitosis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of vasoconstriction|negative regulation of vasodilation|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|positive regulation of fibroblast proliferation|blood vessel morphogenesis|blood vessel morphogenesis|positive regulation of smooth muscle cell proliferation|positive regulation of smooth muscle cell proliferation|regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|positive regulation of chemotaxis|positive regulation of cell division|cell chemotaxis|branching involved in salivary gland morphogenesis|epithelial cell proliferation involved in salivary gland morphogenesis|cardiac vascular smooth muscle cell differentiation|positive regulation of protein tyrosine kinase activity|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cellular response to growth factor stimulus|cellular response to mycophenolic acid|positive regulation of glomerular mesangial cell proliferation|metanephric glomerular mesangial cell development|metanephric glomerular mesangial cell proliferation involved in metanephros development|reactive oxygen species metabolic process|positive regulation of calcium ion import|positive regulation of hyaluronan biosynthetic process|positive regulation of reactive oxygen species metabolic process|positive regulation of DNA biosynthetic process|positive regulation of metanephric mesenchymal cell migration|",receptor binding|platelet-derived growth factor receptor binding|platelet-derived growth factor receptor binding|platelet-derived growth factor receptor binding|collagen binding|growth factor activity|superoxide-generating NADPH oxidase activator activity|chemoattractant activity|identical protein binding|protein homodimerization activity|protein heterodimerization activity|platelet-derived growth factor binding|,10,0.2,1.14,10,0,0,0.2,0.782,0.782,0.697,0,0,-1,1.7
ENSMUSG00000046711,HMGA1,high mobility group AT-hook 1,nucleus|nucleus|senescence-associated heterochromatin focus|,"DNA catabolic process, endonucleolytic|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|spermatogenesis|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|sequence-specific DNA binding transcription factor activity|DNA-(apurinic or apyrimidinic site) lyase activity|transcription factor binding|enzyme binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoic acid receptor binding|peroxisome proliferator activated receptor binding|retinoid X receptor binding|5'-deoxyribose-5-phosphate lyase activity|,10,0.2,0.59,10,0.2,0.259,0.2,0.78,0.78,0.698,0,0,-0.8,1.8
ENSMUSG00000022122,EDNRB,endothelin receptor type B,plasma membrane|membrane|integral component of membrane|nuclear membrane|membrane raft|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|neural crest cell migration|positive regulation of protein phosphorylation|regulation of pH|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|peripheral nervous system development|posterior midgut development|regulation of blood pressure|regulation of blood pressure|positive regulation of cell proliferation|negative regulation of neuron maturation|vein smooth muscle contraction|sensory perception of pain|cGMP-mediated signaling|melanocyte differentiation|melanocyte differentiation|melanocyte differentiation|regulation of fever generation|negative regulation of cellular protein metabolic process|response to lipopolysaccharide|enteric smooth muscle cell differentiation|positive regulation of urine volume|positive regulation of renal sodium excretion|epithelial fluid transport|vasoconstriction|vasodilation|negative regulation of apoptotic process|pigmentation|pigmentation|developmental pigmentation|macrophage chemotaxis|response to pain|enteric nervous system development|enteric nervous system development|regulation of epithelial cell proliferation|regulation of sensory perception of pain|positive regulation of penile erection|endothelin receptor signaling pathway|endothelin receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|endothelin receptor activity|endothelin receptor activity|endothelin receptor activity|protein binding|peptide hormone binding|type 1 angiotensin receptor binding|,10,0.4,0.358,10,-0.8,2.55,-0.2,0.773,-0.773,0.699,0,0,-1.4,2
ENSMUSG00000022779,TOP3B,topoisomerase (DNA) III beta,condensed chromosome|nucleus|,DNA topological change|chromosome segregation|,DNA binding|DNA topoisomerase activity|DNA topoisomerase type I activity|isomerase activity|poly(A) RNA binding|,10,0.8,1.06,10,-0.2,1.62,-0.2,0.771,-0.771,0.7,0,0,-0.9,2
ENSMUSG00000037280,GALNT6,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6,Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|,None,"polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-0.4,1.15,10,0,0,-0.3,0.764,-0.764,0.701,0,0,-1.7,1.1
ENSMUSG00000090223,PCP4,Purkinje cell protein 4,nucleus|cytosol|,None,calmodulin binding|,6,0.1,0.0474,6,0.6,1.67,0.5,0.753,0.753,0.703,0,0,-0.9,2
ENSMUSG00000022010,TSC22D1,"TSC22 domain family, member 1",nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|positive regulation of apoptotic process|negative regulation of apoptotic process|",sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.1,0.24,10,0.5,2.28,0.4,0.752,0.752,0.703,0,0,-1.1,1.6
ENSMUSG00000030075,CNTN3,contactin 3,plasma membrane|membrane|anchored component of membrane|,cell adhesion|nervous system development|,None,10,-0.2,0.475,10,-0.1,0.367,-0.2,0.749,-0.749,0.704,0,0,-1.1,1.9
ENSMUSG00000015709,ARNT2,aryl hydrocarbon receptor nuclear translocator 2,nucleus|nucleus|transcription factor complex|cytoplasm|,"response to hypoxia|response to hypoxia|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|central nervous system development|positive regulation of cell proliferation|response to xenobiotic stimulus|response to toxic substance|negative regulation of apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|aryl hydrocarbon receptor binding|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|,10,0.2,0.506,10,0.2,0.307,0.2,0.746,0.746,0.704,0,0,-0.8,1.8
ENSMUSG00000017718,AFMID,arylformamidase,nucleus|cytoplasm|,tryptophan catabolic process|metabolic process|tryptophan catabolic process to kynurenine|,arylformamidase activity|hydrolase activity|,10,0.2,1.01,10,-0.3,0.98,0.2,0.746,0.746,0.704,0,0,-1.5,1.3
ENSMUSG00000028945,RHEB,Ras homolog enriched in brain,intracellular|spliceosomal complex|plasma membrane|membrane|dendrite|neuronal cell body|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|positive regulation of TOR signaling|positive regulation of TOR signaling|,nucleotide binding|GTPase activity|GTP binding|GTP binding|GDP binding|protein kinase binding|metal ion binding|,10,-0.1,0.327,10,-0.3,0.827,-0.2,0.742,-0.742,0.705,0,0,-1.2,1.7
ENSMUSG00000026414,TNNT2,"troponin T2, cardiac",cytoplasm|troponin complex|troponin complex|striated muscle thin filament|myofibril|myofibril|sarcomere|,ATP catabolic process|muscle contraction|muscle contraction|regulation of muscle contraction|heart development|regulation of heart contraction|regulation of heart contraction|muscle filament sliding|negative regulation of ATPase activity|positive regulation of ATPase activity|regulation of muscle filament sliding speed|sarcomere organization|protein heterooligomerization|response to calcium ion|actin crosslink formation|atrial cardiac muscle tissue morphogenesis|ventricular cardiac muscle tissue morphogenesis|ventricular cardiac muscle tissue morphogenesis|cardiac muscle contraction|,"actin binding|structural constituent of cytoskeleton|tropomyosin binding|ATPase activity|troponin C binding|protein binding, bridging|troponin I binding|",10,-0.1,0.648,10,-0.1,0.154,-0.1,0.737,-0.737,0.706,0,0,-1.7,1.1
ENSMUSG00000059857,NTNG1,netrin G1,plasma membrane|membrane|anchored component of membrane|anchored component of plasma membrane|,multicellular organismal development|nervous system development|axonogenesis|cell differentiation|,protein binding|,10,-0.3,0.995,10,-0.1,0.0828,-0.2,0.736,-0.736,0.707,0,0,-1.7,1
ENSMUSG00000023951,VEGFA,vascular endothelial growth factor A,extracellular region|basement membrane|extracellular space|extracellular space|cytoplasm|cytoplasm|plasma membrane|cell surface|membrane|secretory granule|membrane-bounded vesicle|,negative regulation of transcription from RNA polymerase II promoter|angiogenesis|angiogenesis|angiogenesis|angiogenesis|ovarian follicle development|blood vessel development|patterning of blood vessels|response to hypoxia|in utero embryonic development|kidney development|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|vasculature development|blood vessel remodeling|sprouting angiogenesis|cell migration involved in sprouting angiogenesis|positive regulation of neuroblast proliferation|positive regulation of mesenchymal cell proliferation|positive regulation of receptor internalization|basophil chemotaxis|heart morphogenesis|outflow tract morphogenesis|coronary vein morphogenesis|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|mesoderm development|lactation|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of cell shape|positive regulation of signal transduction|positive regulation of endothelial cell migration|positive regulation of gene expression|cell migration|cell migration|cell differentiation|monocyte differentiation|macrophage differentiation|lung development|lung development|positive regulation of cell migration|epithelial cell differentiation|positive regulation of vascular endothelial growth factor receptor signaling pathway|post-embryonic camera-type eye development|positive regulation of protein complex assembly|positive regulation of protein autophosphorylation|activation of protein kinase activity|positive regulation of CREB transcription factor activity|positive regulation of peptidyl-serine phosphorylation|tube formation|endothelial cell chemotaxis|cellular response to vascular endothelial growth factor stimulus|lymph vessel morphogenesis|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor signaling pathway|vascular endothelial growth factor signaling pathway|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway|VEGF-activated neuropilin signaling pathway|growth|T-helper 1 type immune response|eye photoreceptor cell development|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of programmed cell death|positive regulation of vascular permeability|positive regulation of vascular permeability|surfactant homeostasis|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of MAP kinase activity|negative regulation of neuron apoptotic process|positive regulation of blood vessel endothelial cell migration|positive regulation of angiogenesis|positive regulation of angiogenesis|negative regulation of bone resorption|positive regulation of cell adhesion|positive regulation of transcription from RNA polymerase II promoter|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|mRNA stabilization|lung alveolus development|cell maturation|blood vessel morphogenesis|blood vessel morphogenesis|blood vessel morphogenesis|camera-type eye morphogenesis|positive regulation of smooth muscle cell proliferation|neuron development|cardiac muscle fiber development|branching morphogenesis of an epithelial tube|positive regulation of axon extension involved in axon guidance|positive regulation of axon extension involved in axon guidance|artery morphogenesis|positive regulation of epithelial cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|positive chemotaxis|positive regulation of positive chemotaxis|induction of positive chemotaxis|positive regulation of cellular component movement|positive regulation of cell division|positive regulation of focal adhesion assembly|positive regulation of protein kinase B signaling|primitive erythrocyte differentiation|cell chemotaxis|lung vasculature development|lung vasculature development|mammary gland alveolus development|positive regulation of mast cell chemotaxis|cardiac vascular smooth muscle cell development|angiogenesis involved in coronary vascular morphogenesis|coronary artery morphogenesis|positive regulation of transcription from RNA polymerase II promoter in response to hypoxia|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cellular response to hypoxia|dopaminergic neuron differentiation|commissural neuron axon guidance|commissural neuron axon guidance|positive regulation of protein kinase C signaling|positive regulation of cell migration involved in sprouting angiogenesis|positive regulation of branching involved in ureteric bud morphogenesis|regulation of retinal ganglion cell axon guidance|regulation of retinal ganglion cell axon guidance|positive regulation of peptidyl-tyrosine autophosphorylation|positive regulation of p38MAPK cascade|negative regulation of neuron death|positive regulation of lymphangiogenesis|positive regulation of histone deacetylase activity|positive regulation of retinal ganglion cell axon guidance|positive regulation of intracellular signal transduction|positive regulation of protein localization to early endosome|positive regulation of receptor activity|negative regulation of extrinsic apoptotic signaling pathway|,fibronectin binding|receptor binding|cytokine activity|platelet-derived growth factor receptor binding|vascular endothelial growth factor receptor binding|protein binding|growth factor activity|growth factor activity|heparin binding|heparin binding|neuropilin binding|chemoattractant activity|chemoattractant activity|identical protein binding|protein homodimerization activity|vascular endothelial growth factor receptor 1 binding|vascular endothelial growth factor receptor 1 binding|vascular endothelial growth factor receptor 2 binding|vascular endothelial growth factor receptor 2 binding|vascular endothelial growth factor receptor 2 binding|protein heterodimerization activity|receptor agonist activity|extracellular matrix binding|,10,0.3,0.414,10,0.3,0.388,0.3,0.735,0.735,0.707,0,0,-1.3,1.6
ENSMUSG00000001566,MNX1,motor neuron and pancreas homeobox 1,nucleus|,"neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|motor neuron axon guidance|post-embryonic development|spinal cord motor neuron cell fate specification|nerve development|dorsal/ventral neural tube patterning|central nervous system neuron differentiation|neuron differentiation|pancreas development|endocrine pancreas development|cell morphogenesis involved in neuron differentiation|neuron projection morphogenesis|diaphragm development|respiratory system development|",DNA binding|sequence-specific DNA binding|,10,0.7,0.845,10,0.2,0.414,0.3,0.727,0.727,0.708,0,0,-0.6,2
ENSMUSG00000022240,CTNND2,"catenin (cadherin associated protein), delta 2",nucleus|postsynaptic density|cell junction|neuron projection|,"morphogenesis of a branching structure|transcription, DNA-templated|regulation of transcription, DNA-templated|cell adhesion|multicellular organismal development|learning|single organismal cell-cell adhesion|regulation of synaptic plasticity|",None,9,0.1,0.315,9,1.3,2.37,1.2,0.723,0.723,0.709,0,0,-0.8,2
ENSMUSG00000025400,TAC2,tachykinin 2,extracellular region|extracellular vesicular exosome|,tachykinin receptor signaling pathway|neuropeptide signaling pathway|positive regulation of blood pressure|,None,10,-0.7,0.108,10,-0.2,0.906,-0.3,0.716,-0.716,0.711,0,0,-1.9,0.8
ENSMUSG00000032796,LAMA1,"laminin, alpha 1",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basement membrane|basal lamina|laminin-1 complex|laminin-1 complex|laminin-3 complex|extracellular space|cell-cell junction|extracellular matrix|laminin complex|,morphogenesis of an epithelial sheet|cell adhesion|cell surface receptor signaling pathway|tissue development|regulation of cell adhesion|regulation of cell migration|neuron projection development|establishment of epithelial cell apical/basal polarity|regulation of embryonic development|retina development in camera-type eye|epithelial tube branching involved in lung morphogenesis|branching involved in salivary gland morphogenesis|retinal blood vessel morphogenesis|,receptor binding|extracellular matrix structural constituent|protein binding|glycosphingolipid binding|,10,-0.3,0.935,10,-0.1,0.103,-0.2,0.714,-0.714,0.711,0,0,-1.9,0.8
ENSMUSG00000021758,DDX4,DEAD (Asp-Glu-Ala-Asp) box polypeptide 4,nucleus|cytoplasm|cytoplasm|ribonucleoprotein complex|chromatoid body|chromatoid body|perinuclear region of cytoplasm|pi-body|piP-body|,male meiosis I|multicellular organismal development|spermatogenesis|sperm motility|regulation of protein localization|,nucleotide binding|nucleic acid binding|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|,10,-0.2,0.283,10,-0.4,0.62,-0.3,0.712,-0.712,0.712,0,0,-1.7,1
ENSMUSG00000030413,PGLYRP1,peptidoglycan recognition protein 1,extracellular region|extracellular space|cytoplasm|extracellular vesicular exosome|,pattern recognition receptor signaling pathway|pattern recognition receptor signaling pathway|immune system process|apoptotic process|peptidoglycan catabolic process|detection of bacterium|negative regulation of interferon-gamma production|negative regulation of natural killer cell differentiation involved in immune response|defense response to bacterium|growth of symbiont in host|innate immune response|negative regulation of inflammatory response|defense response to Gram-positive bacterium|,cytokine activity|zinc ion binding|N-acetylmuramoyl-L-alanine amidase activity|peptidoglycan receptor activity|peptidoglycan receptor activity|peptidoglycan binding|,10,0.5,1.28,10,-0.4,1.98,-0.3,0.707,-0.707,0.713,0,0,-1.1,1.8
ENSMUSG00000000296,TPD52L1,tumor protein D52-like 1,cytoplasm|early endosome|perinuclear region of cytoplasm|,G2/M transition of mitotic cell cycle|regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of MAP kinase activity|positive regulation of JNK cascade|positive regulation of apoptotic signaling pathway|,identical protein binding|protein homodimerization activity|protein heterodimerization activity|,10,0.3,0.862,10,0.1,0.0169,0.3,0.707,0.707,0.713,0,0,-1.4,1.5
ENSMUSG00000061762,TAC1,tachykinin 1,extracellular region|extracellular space|plasma membrane|axon|neuronal cell body|,"positive regulation of acute inflammatory response|inflammatory response|positive regulation of cytosolic calcium ion concentration|tachykinin receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|long-term memory|regulation of blood pressure|associative learning|response to hormone|negative regulation of heart rate|positive regulation of epithelial cell migration|sensory perception of pain|positive regulation of synaptic transmission, cholinergic|positive regulation of synaptic transmission, GABAergic|positive regulation of renal sodium excretion|positive regulation of action potential|positive regulation of ossification|positive regulation of saliva secretion|response to pain|positive regulation of lymphocyte proliferation|positive regulation of stress fiber assembly|positive regulation of corticosterone secretion|",substance P receptor binding|,8,0.2,0.744,8,-0.2,0.209,0.2,0.703,0.703,0.714,0,0,-1.2,1.8
ENSMUSG00000031976,URB2,URB2 ribosome biogenesis 2 homolog (S. cerevisiae),nucleus|nucleolus|aggresome|,biological_process|,molecular_function|,10,0.7,0.457,10,-0.5,0.51,0.2,0.692,0.692,0.716,0,0,-1.2,1.8
ENSMUSG00000010067,RASSF1,Ras association (RalGDS/AF-6) domain family member 1,nucleus|cytoplasm|cytoskeleton|microtubule|plasma membrane|microtubule cytoskeleton|,cellular response to DNA damage stimulus|cell cycle|cell cycle arrest|signal transduction|Ras protein signal transduction|positive regulation of protein ubiquitination|intracellular signal transduction|protein stabilization|negative regulation of cell cycle arrest|,protein binding|identical protein binding|metal ion binding|protein N-terminus binding|,10,-0.1,0.231,10,1.1,2.47,0.3,0.691,0.691,0.716,0,0,-0.8,2
ENSMUSG00000068115,NINL,ninein-like,cytoplasm|cytoskeleton|microtubule|,biological_process|,calcium ion binding|metal ion binding|,10,-0.1,0.195,10,0.3,1.67,0.2,0.689,0.689,0.717,0,0,-2,0.9
ENSMUSG00000020654,ADCY3,adenylate cyclase 3,nucleus|cytoplasm|plasma membrane|plasma membrane|cilium|membrane|integral component of membrane|membrane raft|,cAMP biosynthetic process|cAMP biosynthetic process|activation of adenylate cyclase activity|sensory perception of smell|sensory perception of smell|cyclic nucleotide biosynthetic process|intracellular signal transduction|response to stimulus|,nucleotide binding|adenylate cyclase activity|adenylate cyclase activity|protein binding|calmodulin binding|ATP binding|calcium- and calmodulin-responsive adenylate cyclase activity|lyase activity|phosphorus-oxygen lyase activity|metal ion binding|,9,0.2,0.872,9,0.1,0.0573,0.2,0.687,0.687,0.717,0,0,-1.1,1.7
ENSMUSG00000024817,UHRF2,"ubiquitin-like, containing PHD and RING finger domains 2",nucleus|nucleus|nucleus|nuclear heterochromatin|,ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|cell cycle|cell proliferation|protein ubiquitination|protein ubiquitination|cell differentiation|protein autoubiquitination|protein autoubiquitination|positive regulation of cell cycle arrest|,"DNA binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|histone binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.8,0.629,10,-0.2,0.665,-0.4,0.686,-0.686,0.717,0,0,-1.9,0.9
ENSMUSG00000058799,NAP1L1,nucleosome assembly protein 1-like 1,nucleus|membrane|,nucleosome assembly|,protein binding|poly(A) RNA binding|,9,0.3,0.903,9,0.1,0.0303,0.3,0.685,0.685,0.718,0,0,-1.3,1.6
ENSMUSG00000057789,BAK1,BCL2-antagonist/killer 1,intracellular|intracellular|mitochondrion|mitochondrion|endoplasmic reticulum|endoplasmic reticulum|cytosol|cytosol|membrane|integral component of membrane|integral component of mitochondrial outer membrane|mitochondrial membrane|pore complex|,leukocyte homeostasis|B cell homeostasis|B cell homeostasis|B cell apoptotic process|release of cytochrome c from mitochondria|release of cytochrome c from mitochondria|blood vessel remodeling|myeloid cell homeostasis|B cell negative selection|apoptotic process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|mitochondrial fusion|cell proliferation|negative regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|response to fungus|response to mycotoxin|establishment or maintenance of transmembrane electrochemical gradient|response to gamma radiation|positive regulation of calcium ion transport into cytosol|negative regulation of gene expression|negative regulation of endoplasmic reticulum calcium ion concentration|negative regulation of peptidyl-serine phosphorylation|cellular response to UV|cellular response to UV|limb morphogenesis|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|regulation of protein homodimerization activity|regulation of protein heterodimerization activity|fibroblast apoptotic process|positive regulation of proteolysis|regulation of mitochondrial membrane permeability|post-embryonic camera-type eye morphogenesis|homeostasis of number of cells|regulation of cell cycle|regulation of mitochondrial membrane potential|vagina development|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|thymocyte apoptotic process|positive regulation of release of cytochrome c from mitochondria|apoptotic signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|activation of cysteine-type endopeptidase activity|positive regulation of endoplasmic reticulum unfolded protein response|apoptotic process involved in patterning of blood vessels|,protein binding|heat shock protein binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|protein heterodimerization activity|chaperone binding|BH domain binding|,9,-0.7,2.04,9,-0.1,0.324,-0.4,0.685,-0.685,0.718,0,0,-2,0.7
ENSMUSG00000038650,RNH1,ribonuclease/angiogenin inhibitor 1,cytoplasm|angiogenin-PRI complex|extracellular vesicular exosome|,negative regulation of catalytic activity|regulation of angiogenesis|,ribonuclease inhibitor activity|,10,-0.1,0.181,10,-0.3,0.828,-0.2,0.685,-0.685,0.718,0,0,-1.7,1
ENSMUSG00000028328,TMOD1,tropomodulin 1,nucleus|cytoplasm|cytoskeleton|COP9 signalosome|membrane|myofibril|cortical cytoskeleton|,muscle contraction|adult locomotory behavior|myofibril assembly|,actin binding|tropomyosin binding|tropomyosin binding|,10,-0.2,0.527,10,-0.2,0.217,-0.2,0.683,-0.683,0.718,0,0,-1.5,1.3
ENSMUSG00000060459,KNG2,kininogen 2,extracellular space|extracellular vesicular exosome|blood microparticle|,negative regulation of endopeptidase activity|,cysteine-type endopeptidase inhibitor activity|receptor binding|,10,-0.2,1.5,10,0,0,-0.2,0.682,-0.682,0.718,0,0,-1.7,1.1
ENSMUSG00000021756,IL6ST,interleukin 6 signal transducer,extracellular space|interleukin-6 receptor complex|oncostatin-M receptor complex|external side of plasma membrane|membrane|membrane|integral component of membrane|dendrite|neuronal cell body membrane|neuronal cell body|cell body|extracellular vesicular exosome|ciliary neurotrophic factor receptor complex|,glycogen metabolic process|triglyceride mobilization|signal transduction|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of Notch signaling pathway|positive regulation of smooth muscle cell migration|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|response to cytokine|oncostatin-M-mediated signaling pathway|positive regulation of T cell proliferation|positive regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of osteoblast differentiation|positive regulation of astrocyte differentiation|leukemia inhibitory factor signaling pathway|negative regulation of cytosolic calcium ion concentration|interleukin-6-mediated signaling pathway|negative regulation of interleukin-6-mediated signaling pathway|interleukin-27-mediated signaling pathway|ciliary neurotrophic factor-mediated signaling pathway|,cytokine receptor activity|ciliary neurotrophic factor receptor activity|interleukin-6 receptor activity|interleukin-6 receptor activity|interleukin-11 receptor activity|leukemia inhibitory factor receptor activity|oncostatin-M receptor activity|ciliary neurotrophic factor receptor binding|interleukin-6 receptor binding|protein binding|growth factor binding|growth factor binding|interleukin-11 binding|interleukin-6 binding|protein heterodimerization activity|,10,-0.2,0.908,10,0,0,-0.1,0.68,-0.68,0.719,0,0,-1.2,1.6
ENSMUSG00000002109,DDB2,damage specific DNA binding protein 2,nucleus|Cul4B-RING E3 ubiquitin ligase complex|protein complex|,protein polyubiquitination|DNA repair|pyrimidine dimer repair|cellular response to DNA damage stimulus|response to UV|histone H2A monoubiquitination|protein autoubiquitination|UV-damage excision repair|,DNA binding|damaged DNA binding|ubiquitin-protein transferase activity|,10,-0.7,0.275,10,-0.3,0.748,-0.3,0.676,-0.676,0.719,0,0,-1.8,1
ENSMUSG00000024399,LTB,lymphotoxin B,extracellular space|plasma membrane|membrane|integral component of membrane|,immune response|gene expression|skin development|positive regulation of interleukin-12 biosynthetic process|lymph node development|,cytokine activity|tumor necrosis factor receptor binding|,10,0.8,0.506,10,0.4,0.485,0.4,0.675,0.675,0.72,0,0,-1,1.8
ENSMUSG00000035757,SELO,selenoprotein O,cellular_component|,biological_process|,molecular_function|,10,-0.4,2.45,10,0.1,0.225,-0.3,0.673,-0.673,0.72,0,0,-1.9,0.8
ENSMUSG00000032475,NCK1,non-catalytic region of tyrosine kinase adaptor protein 1,nucleus|cytoplasm|endoplasmic reticulum|cell-cell junction|vesicle membrane|,regulation of translation|negative regulation of protein kinase activity|actin filament organization|phosphorylation|cell migration|lamellipodium assembly|positive regulation of actin filament polymerization|positive regulation of actin filament polymerization|positive regulation of T cell proliferation|T cell activation|positive regulation of transcription from RNA polymerase II promoter|response to other organism|negative regulation of cell death|,protein kinase inhibitor activity|receptor binding|protein binding|kinase activity|transferase activity|protein kinase regulator activity|protein domain specific binding|receptor tyrosine kinase binding|,10,-0.3,1.2,10,0,0,-0.3,0.673,-0.673,0.72,0,0,-1.6,1.2
ENSMUSG00000032011,THY1,"thymus cell antigen 1, theta",endoplasmic reticulum|cytosol|plasma membrane|external side of plasma membrane|cell surface|membrane|apical plasma membrane|dendrite|growth cone|anchored component of membrane|anchored component of external side of plasma membrane|membrane raft|anchored component of plasma membrane|extracellular vesicular exosome|,angiogenesis|negative regulation of protein kinase activity|cytoskeleton organization|single organismal cell-cell adhesion|negative regulation of cell migration|positive regulation of Rho GTPase activity|positive regulation of GTPase activity|retinal cone cell development|focal adhesion assembly|negative regulation of axonogenesis|T cell receptor signaling pathway|negative regulation of T cell receptor signaling pathway|positive regulation of T cell activation|positive regulation of release of sequestered calcium ion into cytosol|,Rho GTPase activator activity|integrin binding|enzyme binding|protein kinase binding|GPI anchor binding|,10,0.1,0.678,10,0.1,0.0302,0.1,0.653,0.653,0.724,0,0,-0.8,1.9
ENSMUSG00000023961,ENPP4,ectonucleotide pyrophosphatase/phosphodiesterase 4,plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,blood coagulation|hemostasis|metabolic process|positive regulation of blood coagulation|purine ribonucleoside catabolic process|,catalytic activity|hydrolase activity|metal ion binding|bis(5'-adenosyl)-triphosphatase activity|,10,-0.8,1.06,10,0.4,2.5,0.2,0.652,0.652,0.724,0,0,-1.7,1.4
ENSMUSG00000026725,TNN,tenascin N,extracellular region|proteinaceous extracellular matrix|cell surface|,cell-matrix adhesion|axonogenesis|cell growth|cell migration|,integrin binding|identical protein binding|,10,-0.4,1.23,10,-0.1,0.0446,-0.1,0.646,-0.646,0.726,0,0,-1.9,0.7
ENSMUSG00000027447,CST3,cystatin C,extracellular region|basement membrane|extracellular space|cytoplasm|lysosome|multivesicular body|endoplasmic reticulum|axon|nuclear membrane|vesicle|cell projection|neuronal cell body|contractile fiber|perinuclear region of cytoplasm|extracellular vesicular exosome|,defense response|response to oxidative stress|positive regulation of cell proliferation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of programmed cell death|extracellular fibril organization|positive regulation of DNA replication|negative regulation of proteolysis|negative regulation of elastin catabolic process|negative regulation of cell death|,beta-amyloid binding|protease binding|endopeptidase inhibitor activity|cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.5,1.75,10,0,0,-0.3,0.643,-0.643,0.726,0,0,-1.9,0.6
ENSMUSG00000048368,OMD,osteomodulin,extracellular region|proteinaceous extracellular matrix|,cell adhesion|,None,10,0.3,0.61,10,-0.2,0.591,-0.1,0.64,-0.64,0.727,0,0,-1.4,1.5
ENSMUSG00000051306,USP42,ubiquitin specific peptidase 42,cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|spermatogenesis|protein deubiquitination|protein deubiquitination|cell differentiation|,ubiquitin-specific protease activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0.1,0.0862,10,0.2,0.656,0.2,0.634,0.634,0.729,0,0,-1,1.7
ENSMUSG00000040152,THBS1,thrombospondin 1,extracellular region|fibrinogen complex|extracellular space|extracellular space|cytoplasm|endoplasmic reticulum|external side of plasma membrane|cell surface|sarcoplasmic reticulum|secretory granule|extracellular matrix|platelet alpha granule|extracellular vesicular exosome|,activation of MAPK activity|negative regulation of endothelial cell proliferation|negative regulation of cell-matrix adhesion|sprouting angiogenesis|negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of dendritic cell antigen processing and presentation|outflow tract morphogenesis|endocardial cushion development|growth plate cartilage development|growth plate cartilage development|inflammatory response|response to unfolded protein|cell cycle arrest|cell adhesion|response to mechanical stimulus|response to glucose|positive regulation of endothelial cell migration|negative regulation of endothelial cell migration|negative regulation of plasma membrane long-chain fatty acid transport|negative regulation of nitric oxide mediated signal transduction|negative regulation of cGMP-mediated signaling|negative regulation of plasminogen activation|positive regulation of macrophage chemotaxis|positive regulation of fibroblast migration|positive regulation of cell-substrate adhesion|cell migration|negative regulation of angiogenesis|negative regulation of angiogenesis|peptide cross-linking|positive regulation of blood coagulation|positive regulation of cell migration|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|response to magnesium ion|negative regulation of interleukin-12 production|response to endoplasmic reticulum stress|negative regulation of fibroblast growth factor receptor signaling pathway|positive regulation of phosphorylation|positive regulation of tumor necrosis factor biosynthetic process|positive regulation of macrophage activation|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of blood vessel endothelial cell migration|negative regulation of blood vessel endothelial cell migration|engulfment of apoptotic cell|positive regulation of translation|positive regulation of angiogenesis|behavioral response to pain|blood vessel morphogenesis|positive regulation of chemotaxis|response to calcium ion|positive regulation of protein kinase B signaling|negative regulation of fibrinolysis|positive regulation of transforming growth factor beta production|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of endothelial cell apoptotic process|positive regulation of reactive oxygen species metabolic process|,phosphatidylserine binding|fibronectin binding|integrin binding|calcium ion binding|protein binding|heparin binding|fibroblast growth factor binding|low-density lipoprotein particle binding|laminin binding|transforming growth factor beta binding|extracellular matrix binding|fibrinogen binding|collagen V binding|,10,-0.2,0.225,10,-0.2,0.463,-0.2,0.63,-0.63,0.729,0,0,-1.6,1.1
ENSMUSG00000057132,RPGRIP1,retinitis pigmentosa GTPase regulator interacting protein 1,cilium|axoneme|nonmotile primary cilium|cell projection|,visual perception|eye photoreceptor cell development|response to stimulus|retina development in camera-type eye|,protein binding|,9,-0.2,0.972,10,0.7,0.799,-0.2,0.629,-0.629,0.729,0,0,-1.2,1.8
ENSMUSG00000040813,TEX264,testis expressed gene 264,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.1,0.578,10,-0.2,1.1,0.1,0.628,0.628,0.73,0,0,-1.3,1.5
ENSMUSG00000041359,TCL1,T cell lymphoma breakpoint 1,nucleus|cytoplasm|endoplasmic reticulum|cell cortex|intracellular membrane-bounded organelle|pronucleus|,stem cell maintenance|,None,10,-0.3,1.37,10,0.2,0.308,0.2,0.627,0.627,0.73,0,0,-1.5,1.4
ENSMUSG00000076754,TRGV2,T cell receptor gamma variable 2,None,None,None,4,0.2,0.527,4,0.2,0.154,0.2,0.624,0.624,0.731,0,0,-1.4,2
ENSMUSG00000035722,ABCA7,"ATP-binding cassette, sub-family A (ABC1), member 7",intracellular|cytoplasm|endosome|Golgi apparatus|plasma membrane|membrane|integral component of membrane|apical plasma membrane|,ATP catabolic process|transport|phagocytosis|phospholipid scrambling|negative regulation of ATPase activity|positive regulation of ATPase activity|cholesterol efflux|phospholipid efflux|phospholipid efflux|high-density lipoprotein particle assembly|apolipoprotein A-I-mediated signaling pathway|,nucleotide binding|ATP binding|phospholipid transporter activity|ATPase activity|apolipoprotein A-I receptor activity|,10,0.3,1.06,10,0,0,0.3,0.621,0.621,0.731,0,0,-0.9,1.8
ENSMUSG00000038676,UCN,urocortin,extracellular region|axon|dendrite|neuronal cell body|varicosity|perikaryon|axon terminus|,"positive regulation of protein phosphorylation|response to oxidative stress|neuropeptide signaling pathway|learning or memory|feeding behavior|associative learning|aerobic respiration|positive regulation of gene expression|negative regulation of gene expression|pancreatic juice secretion|positive regulation of cell growth|positive regulation of cAMP biosynthetic process|negative regulation of histone deacetylation|neuron projection development|negative regulation of appetite|positive regulation of interleukin-6 production|positive regulation of collagen biosynthetic process|positive regulation of peptidyl-serine phosphorylation|activation of protein kinase A activity|social behavior|gastric emptying|drinking behavior|negative regulation of apoptotic process|negative regulation of catalytic activity|positive regulation of vascular permeability|positive regulation of translation|positive regulation of DNA replication|negative regulation of blood pressure|negative regulation of cell size|positive regulation of vasodilation|negative regulation of hormone secretion|positive regulation of corticotropin secretion|regulation of synaptic transmission, glutamatergic|positive regulation of cardiac muscle contraction|negative regulation of gastric acid secretion|negative regulation of necrotic cell death|negative regulation of cell death|positive regulation of calcium ion import|negative regulation of neuron death|negative regulation of feeding behavior|positive regulation of behavioral fear response|",G-protein coupled receptor binding|hormone activity|histone deacetylase inhibitor activity|corticotropin-releasing hormone receptor 1 binding|corticotropin-releasing hormone receptor 2 binding|,10,1.2,3.33,10,0,0,1.2,0.619,0.619,0.732,0,0,-0.7,3
ENSMUSG00000041096,TSPYL2,TSPY-like 2,nucleus|nucleolus|cytoplasm|centrosome|plasma membrane|,"nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|negative regulation of DNA replication|chromatin modification|negative regulation of cell growth|regulation of protein kinase activity|",None,10,0,0,10,-0.3,1.6,-0.2,0.616,-0.616,0.733,0,0,-1.7,1.1
ENSMUSG00000022346,MYC,myelocytomatosis oncogene,intracellular|nucleus|nucleus|nucleoplasm|nucleolus|cytoplasm|mitochondrion|spindle|nuclear body|axon|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|branching involved in ureteric bud morphogenesis|B cell apoptotic process|positive regulation of mesenchymal cell proliferation|regulation of oxidative phosphorylation|positive regulation of B cell apoptotic process|glucose metabolic process|chromatin remodeling|transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|pyruvate transport|amino acid transport|cellular iron ion homeostasis|activation of cysteine-type endopeptidase activity involved in apoptotic process|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|inner mitochondrial membrane organization|cell cycle arrest|regulation of mitotic cell cycle|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|response to radiation|response to radiation|response to gamma radiation|regulation of gene expression|regulation of gene expression|negative regulation of gene expression|positive regulation of mitochondrial membrane potential|Wnt signaling pathway|protein processing|transformation of host cell by virus|negative regulation of protein binding|regulation of telomere maintenance|cellular response to drug|cellular response to drug|skeletal muscle cell differentiation|middle ear morphogenesis|regulation of apoptotic process|positive regulation of catalytic activity|response to alkaloid|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|pigmentation|canonical Wnt signaling pathway involved in positive regulation of wound healing|canonical Wnt signaling pathway involved in negative regulation of apoptotic process|canonical Wnt signaling pathway involved in positive regulation of apoptotic process|negative regulation of monocyte differentiation|positive regulation of cell cycle|positive regulation of glycolytic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of glucose import|lactic acid secretion|positive regulation of fibroblast proliferation|negative regulation of fibroblast proliferation|skeletal system morphogenesis|positive regulation of epithelial cell proliferation|detection of mechanical stimulus involved in sensory perception of sound|chromosome organization|negative regulation of cell division|canonical Wnt signaling pathway|negative regulation of cell death|positive regulation of metanephric cap mesenchymal cell proliferation|positive regulation of cellular respiration|positive regulation of DNA biosynthetic process|positive regulation of response to DNA damage stimulus|positive regulation of ATP biosynthetic process|positive regulation of apoptotic signaling pathway|positive regulation of apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein complex binding|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|repressing transcription factor binding|E-box binding|,3,0.5,1.3,3,-0.3,0.729,-0.2,0.615,-0.615,0.733,0,0,-1.5,2
ENSMUSG00000034509,MAD2L1BP,MAD2L1 binding protein,nucleus|nucleolus|cytoplasm|cytoskeleton|intracellular membrane-bounded organelle|,mitotic cell cycle checkpoint|mitotic spindle assembly checkpoint|regulation of exit from mitosis|,protein binding|,10,1.4,1.14,10,-0.5,1.56,-0.4,0.614,-0.614,0.733,0,0,-1.2,2.8
ENSMUSG00000027889,AMPD2,adenosine monophosphate deaminase 2,cellular_component|,IMP biosynthetic process|IMP biosynthetic process|nucleotide metabolic process|purine ribonucleoside monophosphate biosynthetic process|IMP salvage|cyclic purine nucleotide metabolic process|energy homeostasis|energy homeostasis|,AMP deaminase activity|AMP deaminase activity|hydrolase activity|deaminase activity|metal ion binding|,10,-0.2,0.85,10,0.3,0.894,-0.2,0.613,-0.613,0.733,0,0,-0.9,1.9
ENSMUSG00000045994,B3GAT1,"beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)",Golgi apparatus|membrane|integral component of membrane|,None,"UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity|glucuronosyltransferase activity|transferase activity|metal ion binding|",10,-0.1,0.275,10,1.1,2.6,-0.2,0.612,-0.612,0.733,0,0,-0.9,2
ENSMUSG00000034730,BAI1,brain-specific angiogenesis inhibitor 1,plasma membrane|membrane|integral component of membrane|,cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|negative regulation of angiogenesis|,transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|,10,0.3,1.2,10,0,0,0.2,0.612,0.612,0.733,0,0,-1.2,1.6
ENSMUSG00000021013,TTC8,tetratricopeptide repeat domain 8,cytoplasm|centrosome|cytoskeleton|plasma membrane|cilium|membrane|photoreceptor connecting cilium|BBSome|BBSome|ciliary basal body|cell projection|,transport|axon guidance|sensory perception of smell|protein transport|olfactory bulb development|cell projection organization|regulation of protein localization|nonmotile primary cilium assembly|multicellular organism growth|cilium assembly|establishment of anatomical structure orientation|camera-type eye photoreceptor cell differentiation|renal tubule development|,RNA polymerase II repressing transcription factor binding|,10,-0.3,0.443,10,0.4,0.373,-0.2,0.611,-0.611,0.734,0,0,-1.5,1.4
ENSMUSG00000024517,GRP,gastrin releasing peptide,extracellular region|extracellular space|,neuropeptide signaling pathway|,neuropeptide hormone activity|,10,0.2,0.773,10,0.1,0.00178,0.2,0.609,0.609,0.734,0,0,-1.1,1.7
ENSMUSG00000036241,UBE2R2,ubiquitin-conjugating enzyme E2R 2,cellular_component|,protein monoubiquitination|protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0.2,0.454,10,-0.4,0.646,-0.3,0.606,-0.606,0.735,0,0,-1.8,0.9
ENSMUSG00000050074,SPINK8,"serine peptidase inhibitor, Kazal type 8",extracellular region|,negative regulation of peptidase activity|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.1,0.0597,10,0.7,1.03,0.8,0.606,0.606,0.735,0,0,-0.6,2
ENSMUSG00000026839,UPP2,uridine phosphorylase 2,cytoplasm|type III intermediate filament|,nucleoside metabolic process|nucleotide catabolic process|,"catalytic activity|uridine phosphorylase activity|uridine phosphorylase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring pentosyl groups|",10,1,1.68,10,0,0,-0.2,0.605,-0.605,0.735,0,0,-0.9,2
ENSMUSG00000018924,ALOX15,arachidonate 15-lipoxygenase,cytoplasm|lipid particle|cytosol|cytosol|plasma membrane|membrane|extrinsic component of cytoplasmic side of plasma membrane|,ossification|negative regulation of adaptive immune response|lipid metabolic process|fatty acid metabolic process|phosphatidylethanolamine biosynthetic process|positive regulation of cell-substrate adhesion|arachidonic acid metabolic process|arachidonic acid metabolic process|arachidonic acid metabolic process|lipoxygenase pathway|lipoxygenase pathway|lipoxygenase pathway|bone mineralization|positive regulation of actin filament polymerization|positive regulation of heterotypic cell-cell adhesion|response to endoplasmic reticulum stress|regulation of peroxisome proliferator activated receptor signaling pathway|cellular response to interleukin-13|wound healing|apoptotic cell clearance|hepoxilin biosynthetic process|oxidation-reduction process|positive regulation of ERK1 and ERK2 cascade|cellular response to calcium ion|regulation of engulfment of apoptotic cell|lipoxin A4 biosynthetic process|,"arachidonate 12-lipoxygenase activity|arachidonate 12-lipoxygenase activity|iron ion binding|phosphatidylinositol-4,5-bisphosphate binding|lipid binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|metal ion binding|hepoxilin-epoxide hydrolase activity|arachidonate 15-lipoxygenase activity|arachidonate 15-lipoxygenase activity|hepoxilin A3 synthase activity|dioxygenase activity|",10,0.3,1.03,10,0.1,0.169,0.2,0.601,0.601,0.736,0,0,-1.3,1.5
ENSMUSG00000055737,GHR,growth hormone receptor,extracellular region|extracellular space|nucleus|nucleus|cytoplasm|mitochondrion|plasma membrane|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|extrinsic component of membrane|neuronal cell body|receptor complex|growth hormone receptor complex|,activation of MAPK activity|allantoin metabolic process|citrate metabolic process|2-oxoglutarate metabolic process|succinate metabolic process|oxaloacetate metabolic process|isoleucine metabolic process|valine metabolic process|creatine metabolic process|fatty acid metabolic process|endocytosis|JAK-STAT cascade|hormone-mediated signaling pathway|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|taurine metabolic process|response to estradiol|cellular response to hormone stimulus|regulation of multicellular organism growth|positive regulation of multicellular organism growth|activation of Janus kinase activity|activation of JAK2 kinase activity|multicellular organismal metabolic process|positive regulation of JAK-STAT cascade|creatinine metabolic process|insulin-like growth factor receptor signaling pathway|positive regulation of peptidyl-tyrosine phosphorylation|growth hormone receptor signaling pathway|growth hormone receptor signaling pathway|negative regulation of neuron death|,cytokine receptor activity|growth hormone receptor activity|growth hormone receptor activity|protein binding|peptide hormone binding|peptide hormone binding|growth factor binding|protein kinase binding|protein phosphatase binding|SH2 domain binding|protein homodimerization activity|,10,-0.2,0.41,10,-0.1,0.264,-0.2,0.6,-0.6,0.736,0,0,-1.7,1.1
ENSMUSG00000020108,DDIT4,DNA-damage-inducible transcript 4,intracellular|intracellular|cytoplasm|mitochondrion|,response to hypoxia|response to hypoxia|neuron migration|apoptotic process|brain development|cell proliferation|negative regulation of signal transduction|negative regulation of peptidyl-threonine phosphorylation|neuron differentiation|negative regulation of TOR signaling|negative regulation of TOR signaling|negative regulation of peptidyl-serine phosphorylation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|protein complex disassembly|negative regulation of glycolytic process|neurotrophin TRK receptor signaling pathway|defense response to virus|reactive oxygen species metabolic process|positive regulation of neuron death|negative regulation of intracellular signal transduction|,14-3-3 protein binding|,10,0.2,0.53,10,0.1,0.173,0.2,0.596,0.596,0.737,0,0,-0.6,2
ENSMUSG00000056608,CHD9,chromodomain helicase DNA binding protein 9,cellular_component|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|chromatin modification|","nucleotide binding|DNA binding|helicase activity|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|",10,-0.1,0.13,10,-0.2,0.697,-0.1,0.594,-0.594,0.737,0,0,-1.8,1
ENSMUSG00000021207,AKR1C21,"aldo-keto reductase family 1, member C21",cytoplasm|cytosol|extracellular vesicular exosome|,lipid metabolic process|steroid biosynthetic process|G-protein coupled receptor signaling pathway|steroid metabolic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|alditol:NADP+ 1-oxidoreductase activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|prostaglandin F receptor activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|phenanthrene 9,10-monooxygenase activity|acetoin dehydrogenase activity|carboxylic acid binding|bile acid binding|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|androsterone dehydrogenase activity|androsterone dehydrogenase (B-specific) activity|ketosteroid monooxygenase activity|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,-0.1,0.559,10,0.1,0.113,-0.1,0.588,-0.588,0.738,0,0,-1.1,1.8
ENSMUSG00000040957,CABLES1,CDK5 and Abl enzyme substrate 1,nucleus|cytoplasm|cell projection|,G1/S transition of mitotic cell cycle|cell cycle|nervous system development|cell division|regulation of cell division|regulation of cell cycle|,protein binding|cyclin-dependent protein serine/threonine kinase regulator activity|,10,-0.2,1.02,10,0.1,0.0682,-0.1,0.586,-0.586,0.739,0,0,-1.4,1.6
ENSMUSG00000028681,PTCH2,patched homolog 2,membrane|integral component of membrane|,epidermis development|hair cycle|skin development|,smoothened binding|hedgehog receptor activity|hedgehog family protein binding|,10,0.8,3.15,10,-0.2,1.11,0.4,0.579,0.579,0.74,0,0,-0.6,2
ENSMUSG00000070327,RNF213,ring finger protein 213,cytoplasm|membrane|,ATP catabolic process|protein ubiquitination|protein autoubiquitination|,"nucleotide binding|ubiquitin-protein transferase activity|ATP binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ATPase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,1.42,10,0.2,1.09,-0.2,0.579,-0.579,0.74,0,0,-1.5,1.2
ENSMUSG00000048416,MLF1,myeloid leukemia factor 1,nucleus|nucleus|cytoplasm|,"myeloid progenitor cell differentiation|transcription, DNA-templated|cell cycle|cell cycle arrest|multicellular organismal development|cell differentiation|",DNA binding|protein binding|protein domain specific binding|,10,-1.1,2.29,10,0,0,-1,0.571,-0.571,0.742,0,0,-2,1.5
ENSMUSG00000021537,CETN3,centrin 3,cytoplasm|centrosome|centriole|cytoskeleton|photoreceptor connecting cilium|ciliary transition zone|ciliary basal body|intermediate filament cytoskeleton|,cell cycle|mitotic nuclear division|biological_process|cell division|,calcium ion binding|microtubule binding|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,-0.3,0.61,10,0.1,0.312,-0.2,0.568,-0.568,0.743,0,0,-1.4,1.4
ENSMUSG00000029915,CLEC5A,"C-type lectin domain family 5, member a",plasma membrane|cell surface|membrane|integral component of membrane|,osteoblast development|immune system process|response to virus|response to virus|negative regulation of myeloid cell apoptotic process|negative regulation of apoptotic process|innate immune response|innate immune response|positive regulation of cytokine secretion|,virus receptor activity|virus receptor activity|protein binding|carbohydrate binding|,10,-0.4,1.91,10,1.4,1.7,-0.2,0.563,-0.563,0.744,0,0,-1.1,2
ENSMUSG00000063727,TNFRSF11B,"tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)",extracellular region|proteinaceous extracellular matrix|extracellular space|,apoptotic process|signal transduction|extracellular matrix organization|negative regulation of odontogenesis of dentin-containing tooth|negative regulation of bone resorption|,None,10,-0.3,0.642,10,0.2,0.359,0.1,0.562,0.562,0.744,0,0,-1.2,1.7
ENSMUSG00000007080,POLE,"polymerase (DNA directed), epsilon",nucleus|cytoplasm|plasma membrane|epsilon DNA polymerase complex|,"G1/S transition of mitotic cell cycle|DNA synthesis involved in DNA repair|nucleobase-containing compound metabolic process|DNA replication|DNA-dependent DNA replication|DNA repair|base-excision repair, gap-filling|nucleotide-excision repair, DNA gap filling|cellular response to DNA damage stimulus|DNA biosynthetic process|","nucleotide binding|nucleic acid binding|DNA binding|chromatin binding|DNA-directed DNA polymerase activity|zinc ion binding|transferase activity|nucleotidyltransferase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",6,0.6,1.4,7,0.1,0.0709,0.2,0.558,0.558,0.745,0,0,-1,2
ENSMUSG00000018830,MYH11,"myosin, heavy polypeptide 11, smooth muscle",stress fiber|cytoplasm|muscle myosin complex|myosin complex|smooth muscle contractile fiber|myosin filament|,smooth muscle contraction|smooth muscle contraction|elastic fiber assembly|cardiac muscle fiber development|,nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|structural constituent of muscle|,10,-1.1,3.65,10,0,0,-1.1,0.552,-0.552,0.746,0,0,-2,1.2
ENSMUSG00000046768,RHOJ,"ras homolog gene family, member J",intracellular|plasma membrane|membrane|,GTP catabolic process|small GTPase mediated signal transduction|Rho protein signal transduction|regulation of cell shape|actin cytoskeleton organization|actin cytoskeleton organization|retina vasculature morphogenesis in camera-type eye|,nucleotide binding|GTPase activity|protein binding|GTP binding|,10,0,0,10,-0.3,1.31,-0.2,0.552,-0.552,0.746,0,0,-1.5,1.4
ENSMUSG00000031732,PHLPP2,PH domain and leucine rich repeat protein phosphatase 2,photoreceptor inner segment|nucleus|cytoplasm|membrane|photoreceptor outer segment membrane|,protein dephosphorylation|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,0.3,0.866,10,0.1,0.00902,0.3,0.552,0.552,0.746,0,0,-1.1,1.7
ENSMUSG00000025927,TFAP2B,transcription factor AP-2 beta,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|kidney development|renal water homeostasis|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|magnesium ion homeostasis|regulation of BMP signaling pathway|forelimb morphogenesis|hindlimb morphogenesis|positive regulation of urine volume|aorta morphogenesis|glucose homeostasis|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|regulation of cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|sympathetic nervous system development|regulation of insulin secretion|phosphate ion homeostasis|calcium ion homeostasis|potassium ion homeostasis|sodium ion homeostasis|distal tubule development|collecting duct development|ductus arteriosus closure|cellular ammonia homeostasis|cellular creatinine homeostasis|cellular urea homeostasis|",RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription corepressor activity|enhancer sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription coactivator activity|transcription corepressor activity|protein binding|protein homodimerization activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|,10,0.4,2.35,9,0,0,0.3,0.55,0.55,0.747,0,0,-0.7,1.9
ENSMUSG00000025650,COL7A1,"collagen, type VII, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|basement membrane|extracellular space|,cell adhesion|negative regulation of peptidase activity|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|identical protein binding|,10,-0.2,0.499,10,-0.5,0.473,-0.2,0.55,-0.55,0.747,0,0,-1.8,1
ENSMUSG00000023027,ATF1,activating transcription factor 1,nucleus|transcription factor complex|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of neuron projection development|cellular protein complex assembly|positive regulation of DNA replication|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein complex binding|sequence-specific DNA binding|protein heterodimerization activity|,10,-0.3,1.19,10,0,0,-0.2,0.544,-0.544,0.748,0,0,-1.6,1.2
ENSMUSG00000001467,CYP51,"cytochrome P450, family 51",endoplasmic reticulum|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,"lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|sterol biosynthetic process|cholesterol biosynthetic process via 24,25-dihydrolanosterol|oxidation-reduction process|demethylation|demethylation|","monooxygenase activity|iron ion binding|sterol 14-demethylase activity|sterol 14-demethylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|",10,0,0,10,0.3,1.47,0.2,0.54,0.54,0.749,0,0,-0.7,2
ENSMUSG00000041362,4930506M07RIK,RIKEN cDNA 4930506M07 gene,microtubule|growth cone|cell projection|axonal growth cone|,multicellular organismal development|axonogenesis|neuron projection morphogenesis|membrane depolarization|regulation of establishment of cell polarity|regulation of neuron migration|,protein binding|kinase binding|,10,-0.8,1.05,10,0,0,-0.7,0.538,-0.538,0.749,0,0,-2,0.8
ENSMUSG00000025545,CLYBL,citrate lyase beta like,mitochondrion|,biological_process|,molecular_function|catalytic activity|lyase activity|metal ion binding|,10,-0.2,0.409,10,-0.1,0.182,-0.1,0.536,-0.536,0.75,0,0,-1.6,1.2
ENSMUSG00000027381,BCL2L11,BCL2-like 11 (apoptosis facilitator),intracellular|cytoplasm|mitochondrion|mitochondrion|mitochondrion|cytosol|microtubule|membrane|extrinsic component of membrane|intracellular membrane-bounded organelle|BIM-BCL-xl complex|BIM-BCL-2 complex|,in utero embryonic development|leukocyte homeostasis|leukocyte homeostasis|B cell homeostasis|B cell homeostasis|B cell apoptotic process|kidney development|lymphocyte homeostasis|lymphocyte homeostasis|myeloid cell homeostasis|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell-matrix adhesion|spermatogenesis|male gonad development|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|post-embryonic development|positive regulation of cell death|mammary gland development|positive regulation of protein homooligomerization|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|tube formation|odontogenesis of dentin-containing tooth|regulation of apoptotic process|T cell homeostasis|T cell homeostasis|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of neuron apoptotic process|ear development|positive regulation of cell cycle|regulation of organ growth|developmental pigmentation|regulation of developmental pigmentation|spleen development|thymus development|post-embryonic organ morphogenesis|positive regulation of apoptotic process by virus|cellular process regulating host cell cycle in response to virus|thymocyte apoptotic process|positive regulation of release of cytochrome c from mitochondria|extrinsic apoptotic signaling pathway in absence of ligand|extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of mitochondrial membrane permeability involved in apoptotic process|apoptotic process involved in embryonic digit morphogenesis|positive regulation of fibroblast apoptotic process|positive regulation of intrinsic apoptotic signaling pathway|,protein binding|microtubule binding|microtubule binding|,10,0,0,10,0.3,1.03,0.3,0.535,0.535,0.75,0,0,-0.8,1.9
ENSMUSG00000078651,AOC2,"amine oxidase, copper containing 2 (retina-specific)",cellular_component|,catecholamine metabolic process|amine metabolic process|oxidation-reduction process|,copper ion binding|primary amine oxidase activity|oxidoreductase activity|metal ion binding|quinone binding|tryptamine:oxygen oxidoreductase (deaminating) activity|aminoacetone:oxygen oxidoreductase(deaminating) activity|aliphatic-amine oxidase activity|phenethylamine:oxygen oxidoreductase (deaminating) activity|,9,0.5,0.812,9,0.1,0.105,0.1,0.522,0.522,0.753,0,0,-0.8,2
ENSMUSG00000036904,FZD8,frizzled homolog 8 (Drosophila),cytoplasm|Golgi apparatus|plasma membrane|membrane|integral component of membrane|cell projection|,negative regulation of transcription from RNA polymerase II promoter|positive regulation of protein phosphorylation|vasculature development|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|multicellular organismal development|axonogenesis|brain development|gonad development|embryo development|Wnt signaling pathway|T cell differentiation in thymus|positive regulation of JUN kinase activity|positive regulation of transcription from RNA polymerase II promoter|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|receptor binding|protein binding|Wnt-protein binding|PDZ domain binding|PDZ domain binding|PDZ domain binding|ubiquitin protein ligase binding|Wnt-activated receptor activity|,9,-0.2,0.569,9,0.7,0.735,-0.2,0.52,-0.52,0.754,0,0,-1.2,1.8
ENSMUSG00000026278,BOK,BCL2-related ovarian killer,nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|mitochondrial membrane|,apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|intrinsic apoptotic signaling pathway in response to DNA damage|regulation of apoptotic process|positive regulation of apoptotic process|neuron apoptotic process|intrinsic apoptotic signaling pathway by p53 class mediator|extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of execution phase of apoptosis|,protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|BH domain binding|,10,0.5,0.605,10,0.3,0.285,0.4,0.52,0.52,0.754,0,0,-1.1,1.8
ENSMUSG00000038456,DENND2A,DENN/MADD domain containing 2A,cytoplasm|cytoskeleton|actin cytoskeleton|,"transport|protein transport|positive regulation of Rab GTPase activity|retrograde transport, endosome to Golgi|",guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,0.1,0.146,10,0.1,0.418,0.1,0.516,0.516,0.755,0,0,-0.9,1.9
ENSMUSG00000027298,TYRO3,TYRO3 protein tyrosine kinase 3,intracellular|cell|nucleus|nuclear envelope|endoplasmic reticulum membrane|plasma membrane|membrane|integral component of membrane|,natural killer cell differentiation|protein phosphorylation|cell adhesion|spermatogenesis|phosphorylation|peptidyl-tyrosine phosphorylation|forebrain cell migration|platelet activation|secretion by cell|negative regulation of toll-like receptor signaling pathway|substrate adhesion-dependent cell spreading|ovulation cycle|apoptotic cell clearance|protein kinase B signaling|protein kinase B signaling|negative regulation of neuron apoptotic process|negative regulation of innate immune response|protein autophosphorylation|negative regulation of inflammatory response|negative regulation of lymphocyte activation|vagina development|neuron cellular homeostasis|platelet aggregation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphatidylinositol 3-kinase binding|protein heterodimerization activity|",10,-0.2,0.616,10,-0.1,0.00909,-0.1,0.514,-0.514,0.755,0,0,-1.5,1.5
ENSMUSG00000033004,MYCBP2,MYC binding protein 2,nucleus|microtubule cytoskeleton|membrane|axon|,"transcription, DNA-templated|regulation of transcription, DNA-templated|motor neuron axon guidance|branchiomotor neuron axon guidance|central nervous system projection neuron axonogenesis|regulation of protein localization|negative regulation of protein catabolic process|cell morphogenesis involved in neuron differentiation|regulation of cytoskeleton organization|","ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.3,1.17,0.1,0.514,0.514,0.755,0,0,-0.9,1.8
ENSMUSG00000053553,3110082I17RIK,RIKEN cDNA 3110082I17 gene,cellular_component|,biological_process|,poly(A) RNA binding|,10,0.5,0.93,10,0,0,0.5,0.513,0.513,0.755,0,0,-0.7,1.9
ENSMUSG00000029646,CDX2,caudal type homeobox 2,condensed nuclear chromosome|intracellular|cell|nucleus|nucleus|transcriptional repressor complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|blood vessel development|blastocyst development|trophectodermal cell differentiation|trophectodermal cell differentiation|placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|pattern specification process|positive regulation of cell proliferation|endosome to lysosome transport|anterior/posterior pattern specification|cell differentiation|somatic stem cell maintenance|establishment or maintenance of epithelial cell apical/basal polarity|positive regulation of cell differentiation|positive regulation of cell differentiation|positive regulation of transcription, DNA-templated|labyrinthine layer development|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|sequence-specific DNA binding|,10,0,0,10,-0.4,2.07,-0.2,0.513,-0.513,0.755,0,0,-1.4,1.7
ENSMUSG00000051747,TTN,titin,condensed nuclear chromosome|nucleus|cytoplasm|Golgi apparatus|muscle myosin complex|striated muscle thin filament|myofibril|sarcomere|Z disc|Z disc|M band|M band|A band|I band|I band|extracellular vesicular exosome|,in utero embryonic development|heart morphogenesis|cardiac muscle hypertrophy|protein phosphorylation|muscle contraction|adult heart development|skeletal muscle thin filament assembly|skeletal muscle myosin thick filament assembly|forward locomotion|sarcomere organization|sarcomere organization|sarcomere organization|regulation of protein kinase activity|cardiac muscle fiber development|sarcomerogenesis|regulation of catalytic activity|response to calcium ion|striated muscle cell development|cardiac myofibril assembly|cardiac myofibril assembly|cardiac muscle tissue morphogenesis|cardiac muscle contraction|,protease binding|protein serine/threonine kinase activity|structural constituent of cytoskeleton|calcium ion binding|protein binding|calmodulin binding|structural constituent of muscle|enzyme binding|protein kinase binding|telethonin binding|identical protein binding|actinin binding|protein self-association|actin filament binding|muscle alpha-actinin binding|,9,-0.3,0.493,9,0.2,0.779,0.2,0.509,0.509,0.756,0,0,-1.2,1.9
ENSMUSG00000036639,NUDT1,nudix (nucleoside diphosphate linked moiety X)-type motif 1,nucleus|cytoplasm|mitochondrion|mitochondrial matrix|membrane|cytoplasmic vesicle|extracellular vesicular exosome|,GTP catabolic process|purine nucleotide catabolic process|ATP catabolic process|dGTP catabolic process|dGTP catabolic process|DNA repair|DNA protection|dATP catabolic process|,"RNA binding|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|hydrolase activity|snoRNA binding|8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity|metal ion binding|ATP diphosphatase activity|",10,0.1,0.442,10,-0.3,1.05,0.1,0.509,0.509,0.756,0,0,-1.5,1.3
ENSMUSG00000025269,APEX2,apurinic/apyrimidinic endonuclease 2,intracellular|nucleus|cytoplasm|mitochondrion|mitochondrial inner membrane|,"DNA catabolic process, endonucleolytic|DNA catabolic process, exonucleolytic|DNA repair|base-excision repair|DNA recombination|cellular response to DNA damage stimulus|cell cycle|",DNA binding|DNA-(apurinic or apyrimidinic site) lyase activity|nuclease activity|endonuclease activity|exonuclease activity|zinc ion binding|double-stranded DNA 3'-5' exodeoxyribonuclease activity|hydrolase activity|lyase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0.5,1.25,10,0,0,0.1,0.508,0.508,0.756,0,0,-0.9,1.8
ENSMUSG00000029512,ULK1,unc-51 like kinase 1,pre-autophagosomal structure|cytoplasm|autophagic vacuole|cytosol|cytosol|membrane|cytoplasmic vesicle membrane|pre-autophagosomal structure membrane|pre-autophagosomal structure membrane|Atg1p signaling complex|neuron projection|neuronal cell body|ULK1-ATG13-FIP200 complex|ULK1-ATG13-FIP200 complex|,autophagic vacuole assembly|protein phosphorylation|autophagy|signal transduction|Ras protein signal transduction|axonogenesis|protein localization|regulation of autophagy|regulation of autophagy|positive regulation of autophagy|positive regulation of macroautophagy|phosphorylation|cerebellar granule cell differentiation|radial glia guided migration of cerebellar granule cell|neuron projection regeneration|neuron projection development|neuron projection development|receptor internalization|cellular response to nutrient levels|response to starvation|protein autophosphorylation|protein autophosphorylation|negative regulation of collateral sprouting|axon extension|regulation of neurotrophin TRK receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rab GTPase binding|protein kinase binding|protein complex binding|",10,-0.1,0.41,10,-0.1,0.145,-0.1,0.507,-0.507,0.757,0,0,-1.5,1.4
ENSMUSG00000012609,TTLL5,"tubulin tyrosine ligase-like family, member 5",nucleus|cytoplasm|centrosome|cytoskeleton|cilium|cell projection|,"transcription, DNA-templated|cellular protein modification process|spermatogenesis|sperm axoneme assembly|fertilization|protein polyglutamylation|sperm motility|",molecular_function|ligase activity|,10,0.7,0.0539,10,-0.8,2.09,0.2,0.506,0.506,0.757,0,0,-1.8,1.4
ENSMUSG00000044352,SOWAHA,sosondowah ankyrin repeat domain family member A,cellular_component|,biological_process|,molecular_function|,10,0.3,0.804,10,-0.3,0.706,0.2,0.501,0.501,0.758,0,0,-1.3,1.5
ENSMUSG00000021549,RASA1,RAS p21 protein activator 1,ruffle|cytoplasm|plasma membrane|intrinsic component of the cytoplasmic side of the plasma membrane|,negative regulation of cell-matrix adhesion|negative regulation of cell adhesion|signal transduction|regulation of actin filament polymerization|positive regulation of Ras GTPase activity|negative regulation of Ras protein signal transduction|,glycoprotein binding|GTPase activator activity|Ras GTPase activator activity|receptor binding|protein binding|GTPase binding|,10,-0.2,0.131,10,0.2,0.551,0.1,0.498,0.498,0.759,0,0,-1.2,1.7
ENSMUSG00000037225,FGF2,fibroblast growth factor 2,extracellular region|extracellular space|nucleus|nucleus|cytoplasm|cytosol|,"activation of MAPKK activity|angiogenesis|angiogenesis|branching involved in ureteric bud morphogenesis|organ induction|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|cell migration involved in sprouting angiogenesis|phosphatidylinositol biosynthetic process|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|embryo development ending in birth or egg hatching|glial cell differentiation|positive regulation of endothelial cell migration|positive regulation of gene expression|negative regulation of fibroblast migration|positive regulation of phospholipase C activity|substantia nigra development|positive regulation of cerebellar granule cell precursor proliferation|cell differentiation|hyaluronan catabolic process|lung development|lung development|inositol phosphate biosynthetic process|positive regulation of cell fate specification|positive regulation of blood vessel endothelial cell migration|negative regulation of blood vessel endothelial cell migration|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of cell differentiation|positive regulation of osteoblast differentiation|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of retinal cell programmed cell death|positive regulation of smooth muscle cell proliferation|response to axon injury|stem cell development|positive regulation of epithelial cell proliferation|positive chemotaxis|release of sequestered calcium ion into cytosol|regulation of cell cycle|positive regulation of cell division|positive regulation of protein kinase B signaling|cardiac muscle cell proliferation|positive regulation of cardiac muscle cell proliferation|corticotropin hormone secreting cell differentiation|thyroid-stimulating hormone-secreting cell differentiation|negative regulation of cell death|chondroblast differentiation|mammary gland epithelial cell differentiation|angiogenesis involved in coronary vascular morphogenesis|negative regulation of wound healing|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of canonical Wnt signaling pathway|",receptor binding|fibroblast growth factor receptor binding|fibroblast growth factor receptor binding|cytokine activity|protein binding|growth factor activity|growth factor activity|heparin binding|ligand-dependent nuclear receptor transcription coactivator activity|chemoattractant activity|,10,0,0,10,0.4,1.16,0.2,0.497,0.497,0.759,0,0,-0.6,2
ENSMUSG00000014776,NOL3,nucleolar protein 3 (apoptosis repressor with CARD domain),nucleus|mitochondrion|mitochondrion|sarcoplasm|,response to hypoxia|mRNA processing|RNA splicing|regulation of gene expression|response to injury involved in regulation of muscle adaptation|regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|,protein binding|identical protein binding|,10,-0.3,1.48,10,0.2,0.332,-0.2,0.496,-0.496,0.759,0,0,-1.6,1.1
ENSMUSG00000032855,PKD1,polycystic kidney disease 1 homolog,polycystin complex|nucleus|cytoplasm|Golgi apparatus|plasma membrane|plasma membrane|cilium|membrane|integral component of membrane|basolateral plasma membrane|lateral plasma membrane|motile primary cilium|cell projection|extracellular vesicular exosome|,cartilage condensation|blood vessel development|in utero embryonic development|in utero embryonic development|kidney development|kidney development|liver development|embryonic placenta development|protein export from nucleus|nitrogen compound metabolic process|cation transport|calcium ion transport|cell cycle arrest|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|JAK-STAT cascade|heart development|single organismal cell-cell adhesion|peptidyl-serine phosphorylation|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|positive regulation of protein binding|ion transmembrane transport|response to fluid shear stress|cytoplasmic sequestering of transcription factor|positive regulation of transcription from RNA polymerase II promoter|branching morphogenesis of an epithelial tube|detection of mechanical stimulus|detection of mechanical stimulus|regulation of mitotic spindle organization|placenta blood vessel development|regulation of proteasomal protein catabolic process|regulation of proteasomal protein catabolic process|calcium ion transmembrane transport|renal system development|,cation channel activity|calcium channel activity|protein binding|protein kinase binding|protein domain specific binding|carbohydrate binding|ion channel binding|,10,-0.6,2.76,10,0.3,0.582,0.3,0.495,0.495,0.759,0,0,-1.7,1.2
ENSMUSG00000056486,CHN1,chimerin 1,intracellular|,signal transduction|nervous system development|motor neuron axon guidance|regulation of Rac GTPase activity|intracellular signal transduction|ephrin receptor signaling pathway|regulation of axonogenesis|regulation of axonogenesis|,GTPase activator activity|protein binding|metal ion binding|ephrin receptor binding|,10,0,0,10,-0.2,1.03,-0.2,0.495,-0.495,0.759,0,0,-1.8,0.9
ENSMUSG00000032053,POU2AF1,"POU domain, class 2, associating factor 1",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|protein binding|,10,-0.2,0.472,10,0.2,1.21,0.2,0.493,0.493,0.76,0,0,-1.6,1.3
ENSMUSG00000049281,SCN3B,"sodium channel, voltage-gated, type III, beta",voltage-gated sodium channel complex|plasma membrane|membrane|integral component of membrane|Z disc|,transport|ion transport|sodium ion transport|positive regulation of heart rate|positive regulation of sodium ion transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|membrane depolarization|cardiac muscle contraction|regulation of atrial cardiac muscle cell membrane depolarization|regulation of atrial cardiac muscle cell membrane depolarization|regulation of ventricular cardiac muscle cell membrane depolarization|cardiac conduction|protein localization to plasma membrane|cardiac muscle cell action potential involved in contraction|ventricular cardiac muscle cell action potential|ventricular cardiac muscle cell action potential|membrane depolarization during action potential|membrane depolarization during cardiac muscle cell action potential|membrane depolarization during cardiac muscle cell action potential|atrial cardiac muscle cell action potential|SA node cell to atrial cardiac muscle cell communication|regulation of heart rate by cardiac conduction|regulation of sodium ion transmembrane transporter activity|,voltage-gated ion channel activity|sodium channel activity|sodium channel regulator activity|ion channel binding|ion channel binding|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|,10,-0.2,0.12,10,-1,1.01,-0.2,0.49,-0.49,0.76,0,0,-2,0.7
ENSMUSG00000026049,TEX30,testis expressed 30,cellular_component|,biological_process|,molecular_function|,10,0.3,1.01,10,0,0,0.2,0.486,0.486,0.761,0,0,-0.9,1.8
ENSMUSG00000055602,TCP10B,t-complex protein 10b,None,None,None,10,0.2,1.13,10,0,0,0.1,0.486,0.486,0.761,0,0,-1.5,1.4
ENSMUSG00000039478,MICU3,"mitochondrial calcium uptake family, member 3",cellular_component|mitochondrion|membrane|integral component of membrane|,biological_process|,calcium ion binding|metal ion binding|,10,0.2,0.459,10,0.1,0.0724,0.2,0.486,0.486,0.761,0,0,-1.1,1.7
ENSMUSG00000029553,TFEC,transcription factor EC,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to heat|",DNA binding|protein dimerization activity|,10,1.4,1.24,10,-0.3,2.3,-0.2,0.486,-0.486,0.761,0,0,-1,2.9
ENSMUSG00000036867,SMAD6,SMAD family member 6,intracellular|nucleus|transcription factor complex|protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|immune response|transforming growth factor beta receptor signaling pathway|zygotic specification of dorsal/ventral axis|negative regulation of cell proliferation|negative regulation of SMAD protein complex assembly|BMP signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|cell-substrate adhesion|intracellular signal transduction|negative regulation of apoptotic process|fat cell differentiation|positive regulation of vasoconstriction|negative regulation of vasodilation|negative regulation of pathway-restricted SMAD protein phosphorylation|cardiac vascular smooth muscle cell development|coronary vasculature morphogenesis|","DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity|ubiquitin protein ligase binding|type I transforming growth factor beta receptor binding|transcription regulatory region DNA binding|metal ion binding|co-SMAD binding|I-SMAD binding|R-SMAD binding|type I activin receptor binding|",10,-0.7,0.0266,10,-0.3,1.05,-0.3,0.484,-0.484,0.762,0,0,-2,0.5
ENSMUSG00000033174,MGLL,monoglyceride lipase,axon|varicosity|synapse|synapse|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|regulation of signal transduction|lipid catabolic process|arachidonic acid metabolic process|regulation of axon extension|acylglycerol catabolic process|regulation of inflammatory response|regulation of sensory perception of pain|long term synaptic depression|regulation of endocannabinoid signaling pathway|,lipid binding|hydrolase activity|protein homodimerization activity|acylglycerol lipase activity|,10,0.1,0.212,10,0.1,0.309,0.1,0.476,0.476,0.764,0,0,-1.1,1.7
ENSMUSG00000075334,RPRM,"reprimo, TP53 dependent G2 arrest mediator candidate",cytoplasm|membrane|integral component of membrane|,cell cycle arrest|regulation of mitotic cell cycle|,molecular_function|,10,0.4,1.08,10,-0.2,0.44,0.4,0.475,0.475,0.764,0,0,-0.9,1.8
ENSMUSG00000030278,CIDEC,cell death-inducing DFFA-like effector c,intracellular|nucleus|endoplasmic reticulum|lipid particle|cytosol|cytosol|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|lipid particle organization|regulation of apoptotic process|execution phase of apoptosis|",None,9,-0.8,1.65,9,0.1,0.0186,0.4,0.475,0.475,0.764,0,0,-1.8,1.4
ENSMUSG00000029009,MTHFR,"5,10-methylenetetrahydrofolate reductase",cytosol|neuron projection|,methionine metabolic process|metabolic process|methionine biosynthetic process|tetrahydrofolate metabolic process|homocysteine metabolic process|oxidation-reduction process|,catalytic activity|methylenetetrahydrofolate reductase (NAD(P)H) activity|methylenetetrahydrofolate reductase (NAD(P)H) activity|oxidoreductase activity|flavin adenine dinucleotide binding|NADP binding|modified amino acid binding|,10,-0.2,1.23,10,0,0,-0.1,0.472,-0.472,0.765,0,0,-1.7,1.1
ENSMUSG00000020622,NT5C1B,"5'-nucleotidase, cytosolic IB",nucleus|cytoplasm|cytosol|,nucleoside metabolic process|nucleotide metabolic process|dephosphorylation|dephosphorylation|adenosine metabolic process|,nucleotide binding|magnesium ion binding|5'-nucleotidase activity|5'-nucleotidase activity|hydrolase activity|,10,0.3,0.594,10,-0.5,0.843,0.3,0.471,0.471,0.765,0,0,-1.5,1.4
ENSMUSG00000038990,CABLES2,CDK5 and Abl enzyme substrate 2,cellular_component|,cell cycle|biological_process|cell division|regulation of cell division|regulation of cell cycle|,protein binding|cyclin-dependent protein serine/threonine kinase regulator activity|,10,-1,1.77,10,0.6,0.82,0.3,0.47,0.47,0.765,0,0,-2,1.3
ENSMUSG00000024924,VLDLR,very low density lipoprotein receptor,extracellular space|nucleus|coated pit|cell surface|membrane|integral component of membrane|very-low-density lipoprotein particle|receptor complex|apical part of cell|perinuclear region of cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|lipid metabolic process|transport|lipid transport|endocytosis|receptor-mediated endocytosis|steroid metabolic process|cholesterol metabolic process|glycoprotein transport|very-low-density lipoprotein particle clearance|reelin-mediated signaling pathway|positive regulation of protein kinase activity|cellular response to hypoxia|positive regulation of dendrite development|,glycoprotein binding|calcium ion binding|protein binding|very-low-density lipoprotein particle receptor activity|apolipoprotein binding|very-low-density lipoprotein particle binding|glycoprotein transporter activity|reelin receptor activity|calcium-dependent protein binding|,10,1.1,1.81,10,0,0,0.1,0.467,0.467,0.766,0,0,-1.1,2
ENSMUSG00000039997,IFI203,interferon activated gene 203,nucleus|nucleolus|cytoplasm|membrane|,cellular response to interferon-beta|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,9,0.4,0.857,9,-0.2,0.157,-0.2,0.46,-0.46,0.768,0,0,-1.5,1.4
ENSMUSG00000038545,CUL7,cullin 7,intracellular|nucleus|cytoplasm|Golgi apparatus|centrosome|cullin-RING ubiquitin ligase complex|Cul7-RING ubiquitin ligase complex|Cul7-RING ubiquitin ligase complex|perinuclear region of cytoplasm|3M complex|,microtubule cytoskeleton organization|mitotic cytokinesis|vasculogenesis|epithelial to mesenchymal transition|placenta development|ubiquitin-dependent protein catabolic process|apoptotic process|Golgi organization|regulation of mitosis|protein ubiquitination|regulation of apoptotic process|regulation of endothelial cell differentiation|positive regulation of dendrite morphogenesis|,protein binding|ubiquitin protein ligase binding|,10,0.1,0.07,10,0.3,0.987,0.1,0.46,0.46,0.768,0,0,-0.9,1.8
ENSMUSG00000066861,OAS1G,2'-5' oligoadenylate synthetase 1G,nucleus|cytoplasm|,None,2'-5'-oligoadenylate synthetase activity|double-stranded RNA binding|zinc ion binding|,10,-0.1,0.491,10,0.1,0.138,-0.1,0.459,-0.459,0.768,0,0,-1,1.8
ENSMUSG00000027459,FAM110A,"family with sequence similarity 110, member A",cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,0,0,10,-0.3,1.15,-0.1,0.457,-0.457,0.768,0,0,-1.7,1.1
ENSMUSG00000026966,SSNA1,Sjogren's syndrome nuclear autoantigen 1,intracellular|cell|nucleus|cytoplasm|centrosome|centrosome|cytoskeleton|cilium|ciliary basal body|,intraciliary transport|ciliary receptor clustering involved in smoothened signaling pathway|,identical protein binding|,10,-0.2,0.0906,10,-0.2,0.4,-0.2,0.449,-0.449,0.77,0,0,-1.5,1.5
ENSMUSG00000004771,RAB11A,"RAB11A, member RAS oncogene family",cell|cytoplasm|mitochondrion|endosome|trans-Golgi network|plasma membrane|membrane|transport vesicle|axon|cytoplasmic vesicle|cleavage furrow|protein complex|phagocytic vesicle|perinuclear region of cytoplasm|recycling endosome|recycling endosome|extracellular vesicular exosome|,cytokinesis|GTP catabolic process|transport|cell cycle|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|neuron projection development|melanosome transport|positive regulation of axon extension|regulation of long-term neuronal synaptic plasticity|regulation of protein transport|protein localization to plasma membrane|,nucleotide binding|GTPase activity|protein binding|GTP binding|,10,1.1,3.54,9,-0.6,0.175,1.1,0.449,0.449,0.77,0,0,-2.1,2
ENSMUSG00000030230,PLCZ1,"phospholipase C, zeta 1",nucleus|cytoplasm|cytosol|,lipid metabolic process|calcium ion transport|signal transduction|multicellular organismal development|single fertilization|egg activation|lipid catabolic process|intracellular signal transduction|,phosphatidylinositol phospholipase C activity|phospholipase C activity|signal transducer activity|calcium ion binding|phosphoric diester hydrolase activity|hydrolase activity|,10,-0.4,1.75,10,0.2,0.543,0.2,0.445,0.445,0.771,0,0,-1.2,1.7
ENSMUSG00000036561,PPP6R2,"protein phosphatase 6, regulatory subunit 2",cytoplasm|intracellular membrane-bounded organelle|,regulation of phosphoprotein phosphatase activity|,protein phosphatase binding|,10,-0.2,0.265,10,0.4,2.14,0.3,0.439,0.439,0.773,0,0,-0.9,1.9
ENSMUSG00000062818,VMN1R51,vomeronasal 1 receptor 51,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|response to pheromone|,signal transducer activity|G-protein coupled receptor activity|pheromone receptor activity|,10,0,0,10,-0.2,0.864,-0.1,0.433,-0.433,0.774,0,0,-1.6,1.3
ENSMUSG00000012520,PHOX2B,paired-like homeobox 2b,nuclear chromatin|nucleus|,"neuron migration|regulation of respiratory gaseous exchange by neurological system process|noradrenergic neuron differentiation|noradrenergic neuron development|regulation of transcription, DNA-templated|multicellular organismal development|negative regulation of cell proliferation|glial cell differentiation|regulation of gene expression|cell differentiation in hindbrain|hindbrain tangential cell migration|neuron differentiation|skeletal muscle cell differentiation|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell development|autonomic nervous system development|enteric nervous system development|sympathetic nervous system development|parasympathetic nervous system development|inner ear development|efferent axon development in a lateral line nerve|respiratory system development|retrotrapezoid nucleus neuron differentiation|sympathetic ganglion development|dopaminergic neuron differentiation|cellular response to BMP stimulus|neural crest cell migration involved in autonomic nervous system development|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding|,10,0,0,10,-0.3,0.895,-0.1,0.424,-0.424,0.777,0,0,-1.8,0.9
ENSMUSG00000026700,TNFSF4,"tumor necrosis factor (ligand) superfamily, member 4",extracellular space|cell surface|membrane|integral component of membrane|,"blood vessel development|cytokine production|defense response to nematode|acute inflammatory response|positive regulation of immune effector process|positive regulation of T cell cytokine production|regulation of adaptive immune response|positive regulation of type 2 immune response|positive regulation of type 2 immune response|positive regulation of immunoglobulin mediated immune response|inflammatory response|immune response|cholesterol metabolic process|response to virus|negative regulation of interferon-gamma production|negative regulation of interleukin-17 production|positive regulation of interferon-gamma production|positive regulation of interferon-gamma production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-13 production|positive regulation of interleukin-2 production|positive regulation of interleukin-4 production|positive regulation of interleukin-4 production|positive regulation of interleukin-4 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|memory T cell activation|T-helper 2 cell activation|response to nitrogen dioxide|cellular response to nitrogen dioxide|CD4-positive, alpha-beta T cell costimulation|T cell proliferation|positive regulation of activated T cell proliferation|positive regulation of CD4-positive, alpha-beta T cell differentiation|positive regulation of memory T cell differentiation|negative regulation of sequence-specific DNA binding transcription factor activity|innate immune response|negative regulation of regulatory T cell differentiation|negative regulation of T-helper 1 cell differentiation|positive regulation of T-helper 2 cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of alpha-beta T cell proliferation|negative regulation of cytokine secretion|regulation of inflammatory response|positive regulation of inflammatory response|positive regulation of B cell activation|positive regulation of immunoglobulin secretion|negative regulation of T cell apoptotic process|negative regulation of activation-induced cell death of T cells|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|cellular response to prostaglandin E stimulus|chemokine (C-C motif) ligand 11 production|positive regulation of CD4-positive, alpha-beta T cell costimulation|positive regulation of T cell migration|positive regulation of T cell costimulation|positive regulation of memory T cell activation|positive regulation of T-helper 2 cell activation|positive regulation of interleukin-4-dependent isotype switching to IgE isotypes|negative regulation of extrinsic apoptotic signaling pathway|",cytokine activity|tumor necrosis factor receptor binding|tumor necrosis factor receptor superfamily binding|tumor necrosis factor receptor superfamily binding|,10,-0.1,0.0781,10,-0.2,0.421,-0.2,0.42,-0.42,0.778,0,0,-1.6,1.2
ENSMUSG00000030209,GRIN2B,"glutamate receptor, ionotropic, NMDA2B (epsilon 2)",plasma membrane|synaptic vesicle|cell surface|postsynaptic density|postsynaptic density|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|N-methyl-D-aspartate selective glutamate receptor complex|Z disc|cell junction|presynaptic membrane|presynaptic membrane|neuron projection|neuron projection|synaptic cleft|terminal bouton|dendritic spine|synapse|synapse|postsynaptic membrane|neuronal postsynaptic density|,"action potential|behavioral fear response|in utero embryonic development|startle response|startle response|suckling behavior|transport|ion transport|cation transport|calcium ion transport|synaptic transmission|sensory organ development|learning or memory|learning|learning|memory|memory|memory|associative learning|embryo development|positive regulation of cell death|positive regulation of glutamate secretion|ion transmembrane transport|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|fear response|receptor clustering|regulation of MAPK cascade|response to ethanol|response to ethanol|regulation of synaptic plasticity|regulation of neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|behavioral response to pain|rhythmic process|positive regulation of synaptic transmission|detection of mechanical stimulus involved in sensory perception of pain|regulation of postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|calcium ion transmembrane transport|",receptor activity|ionotropic glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|receptor binding|interleukin-1 receptor binding|transporter activity|ion channel activity|extracellular-glutamate-gated ion channel activity|extracellular-glutamate-gated ion channel activity|cation channel activity|calcium channel activity|protein binding|beta-catenin binding|drug binding|zinc ion binding|glycine binding|D2 dopamine receptor binding|ionotropic glutamate receptor binding|neurotransmitter binding|metal ion binding|protein heterodimerization activity|cell adhesion molecule binding|,10,0.2,0.376,10,-0.4,1.09,0.3,0.418,0.418,0.778,0,0,-1.3,1.5
ENSMUSG00000022037,CLU,clusterin,extracellular region|extracellular space|nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|membrane|aggresome|growth cone|extracellular matrix|cytoplasmic vesicle|spherical high-density lipoprotein particle|neuron projection|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|extracellular vesicular exosome|blood microparticle|neurofibrillary tangle|apical dendrite|,cell morphogenesis|microglial cell activation|cell death|positive regulation of cell proliferation|protein import|endocrine pancreas development|central nervous system myelin maintenance|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of protein homooligomerization|positive regulation of tumor necrosis factor production|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of nitric oxide biosynthetic process|positive regulation of cell differentiation|neuron projection morphogenesis|protein stabilization|positive regulation of NF-kappaB transcription factor activity|chaperone-mediated protein complex assembly|response to misfolded protein|chaperone-mediated protein folding|microglial cell proliferation|intrinsic apoptotic signaling pathway|regulation of beta-amyloid clearance|regulation of neuron death|positive regulation of neuron death|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of beta-amyloid formation|regulation of neuronal signal transduction|positive regulation of tau-protein kinase activity|positive regulation of neurofibrillary tangle assembly|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of intrinsic apoptotic signaling pathway|,protein binding|ubiquitin protein ligase binding|misfolded protein binding|,10,0.4,0.736,10,-0.1,0.168,0.1,0.414,0.414,0.779,0,0,-1.1,1.6
ENSMUSG00000045216,HS6ST1,heparan sulfate 6-O-sulfotransferase 1,membrane|integral component of membrane|,"angiogenesis|heparan sulfate proteoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process, enzymatic modification|lung alveolus development|neuron development|labyrinthine layer blood vessel development|","N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0.4,0.584,10,-0.3,1.51,-0.2,0.414,-0.414,0.779,0,0,-1.4,1.5
ENSMUSG00000035834,POLR3G,polymerase (RNA) III (DNA directed) polypeptide G,nuclear chromatin|nuclear chromatin|nucleus|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|,"immune system process|transcription, DNA-templated|transcription initiation from RNA polymerase III promoter|cell proliferation|cell proliferation|positive regulation of interferon-beta production|innate immune response|positive regulation of innate immune response|defense response to virus|",RNA polymerase III activity|,10,-0.3,0.679,10,-0.1,0.065,-0.2,0.412,-0.412,0.78,0,0,-1.8,0.9
ENSMUSG00000032435,DYNC1LI1,dynein cytoplasmic 1 light intermediate chain 1,"chromosome, centromeric region|kinetochore|spindle pole|chromosome|cytoplasm|centrosome|cytoskeleton|cytoplasmic dynein complex|cytoplasmic dynein complex|microtubule|plasma membrane|membrane|dynein complex|",transport|microtubule-based movement|cell cycle|mitotic nuclear division|regulation of centrosome cycle|cell division|positive regulation of mitotic cell cycle spindle assembly checkpoint|,nucleotide binding|motor activity|microtubule motor activity|ATP binding|poly(A) RNA binding|,10,0.1,0.0288,10,0.2,0.688,0.1,0.408,0.408,0.781,0,0,-1.1,1.7
ENSMUSG00000032411,TFDP2,transcription factor Dp 2,nucleus|nuclear envelope|transcription factor complex|,"mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription cofactor activity|protein binding|transcription factor binding|protein domain specific binding|,10,0,0,10,-0.4,1.62,-0.2,0.407,-0.407,0.781,0,0,-1.6,1.4
ENSMUSG00000063011,MSLN,mesothelin,extracellular region|extracellular space|Golgi apparatus|plasma membrane|cell surface|membrane|anchored component of membrane|,cell adhesion|,protein binding|,10,-0.2,0.253,10,0.1,0.369,0.1,0.405,0.405,0.782,0,0,-1.2,1.7
ENSMUSG00000021991,CACNA2D3,"calcium channel, voltage-dependent, alpha2/delta subunit 3",membrane|integral component of membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|metal ion binding|,10,-0.1,0.413,10,0.2,0.539,-0.1,0.4,-0.4,0.783,0,0,-1.1,1.9
ENSMUSG00000025077,DCLRE1A,"DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)",nucleus|,DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|cell division|,None,10,0.8,2.51,10,0,0,0.7,0.399,0.399,0.783,0,0,-0.4,2
ENSMUSG00000003436,DLL3,delta-like 3 (Drosophila),membrane|integral component of membrane|,skeletal system development|skeletal system development|in utero embryonic development|cell fate determination|somitogenesis|somitogenesis|Notch signaling pathway|multicellular organismal development|compartment pattern specification|nervous system development|tissue development|cell differentiation|negative regulation of Notch signaling pathway|paraxial mesoderm development|negative regulation of astrocyte differentiation|negative regulation of neurogenesis|positive regulation of neurogenesis|,Notch binding|Notch binding|protein binding|,10,-0.8,1.05,10,0.1,0.0643,-0.1,0.398,-0.398,0.784,0,0,-2,0.7
ENSMUSG00000020782,LLGL2,lethal giant larvae homolog 2 (Drosophila),cytoplasm|,exocytosis|cell cycle|regulation of establishment or maintenance of cell polarity|cell division|,PDZ domain binding|,10,-0.7,0.463,9,0.3,0.947,0.3,0.397,0.397,0.784,0,0,-1.3,1.9
ENSMUSG00000020866,CACNA1G,"calcium channel, voltage-dependent, T type, alpha 1G subunit",plasma membrane|plasma membrane|membrane|integral component of membrane|dendrite|neuronal cell body|cell body|perinuclear region of cytoplasm|,action potential|regulation of heart rate|transport|ion transport|calcium ion transport|positive regulation of cytosolic calcium ion concentration|synaptic transmission|response to nickel cation|artery smooth muscle contraction|regulation of ion transmembrane transport|regulation of membrane potential|positive regulation of calcium ion-dependent exocytosis|positive regulation of calcium ion-dependent exocytosis|regulation of calcium ion transport|regulation of atrial cardiac muscle cell membrane depolarization|calcium ion transport into cytosol|calcium ion import|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|low voltage-gated calcium channel activity|low voltage-gated calcium channel activity|scaffold protein binding|,10,0.1,0.112,10,0.2,0.39,0.1,0.397,0.397,0.784,0,0,-1.1,1.7
ENSMUSG00000020892,ALOXE3,arachidonate lipoxygenase 3,cytoplasm|,lipid metabolic process|fatty acid metabolic process|sphingolipid metabolic process|sensory perception of pain|arachidonic acid metabolic process|arachidonic acid metabolic process|lipoxygenase pathway|peroxisome proliferator activated receptor signaling pathway|linoleic acid metabolic process|linoleic acid metabolic process|fat cell differentiation|ceramide biosynthetic process|hepoxilin biosynthetic process|hepoxilin biosynthetic process|hepoxilin biosynthetic process|oxidation-reduction process|establishment of skin barrier|,"catalytic activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|isomerase activity|2,3-dihydroxy DDT 1,2-dioxygenase activity|phenanthrene dioxygenase activity|2,2',3-trihydroxybiphenyl dioxygenase activity|1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity|5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity|1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity|protocatechuate 3,4-dioxygenase type II activity|2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity|3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity|2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity|carbazole 1,9a-dioxygenase activity|dihydroxydibenzothiophene dioxygenase activity|1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity|styrene dioxygenase activity|3,4-dihydroxyphenanthrene dioxygenase activity|hydroquinone 1,2-dioxygenase activity|p-cumate 2,3-dioxygenase activity|2,3-dihydroxy-p-cumate dioxygenase activity|3,5-dichlorocatechol 1,2-dioxygenase activity|2-aminophenol 1,6-dioxygenase activity|2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity|chlorocatechol 1,2-dioxygenase activity|catechol dioxygenase activity|dihydroxyfluorene dioxygenase activity|5-aminosalicylate dioxygenase activity|3-hydroxy-2-naphthoate 2,3-dioxygenase activity|benzo(a)pyrene 11,12-dioxygenase activity|benzo(a)pyrene 4,5-dioxygenase activity|4,5-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 9,10-dioxygenase activity|9,10-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 7,8-dioxygenase activity|7,8-dihydroxy benzo(a)pyrene dioxygenase activity|1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity|2-mercaptobenzothiazole dioxygenase activity|pyridine-3,4-diol dioxygenase activity|pyrene dioxygenase activity|4,5-dihydroxypyrene dioxygenase activity|phenanthrene-4-carboxylate dioxygenase activity|tetrachlorobenzene dioxygenase activity|4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity|2,3-dihydroxydiphenyl ether dioxygenase activity|diphenyl ether 1,2-dioxygenase activity|arachidonate 8(S)-lipoxygenase activity|metal ion binding|4-hydroxycatechol 1,2-dioxygenase activity|hepoxilin A3 synthase activity|hepoxilin A3 synthase activity|dioxygenase activity|",10,-0.1,0.0885,10,-0.6,1.42,-0.3,0.393,-0.393,0.785,0,0,-1.9,0.9
ENSMUSG00000031639,TLR3,toll-like receptor 3,intracellular|cytoplasm|lysosomal membrane|endosome|endoplasmic reticulum|cell surface|membrane|integral component of membrane|,microglial cell activation|positive regulation of cytokine production|positive regulation of protein phosphorylation|toll-like receptor signaling pathway|microglial cell activation involved in immune response|immune system process|MyD88-independent toll-like receptor signaling pathway|defense response|inflammatory response|signal transduction|I-kappaB phosphorylation|response to virus|positive regulation of type I interferon production|positive regulation of chemokine production|positive regulation of interferon-beta production|positive regulation of interleukin-12 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of toll-like receptor signaling pathway|toll-like receptor 3 signaling pathway|positive regulation of type III interferon production|positive regulation of NF-kappaB import into nucleus|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to exogenous dsRNA|response to exogenous dsRNA|response to dsRNA|positive regulation of interferon-gamma biosynthetic process|positive regulation of chemokine biosynthetic process|innate immune response|positive regulation of interferon-alpha biosynthetic process|positive regulation of interferon-beta biosynthetic process|positive regulation of interferon-beta biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|positive regulation of inflammatory response|positive regulation of NF-kappaB transcription factor activity|defense response to virus|defense response to virus|cellular response to exogenous dsRNA|extrinsic apoptotic signaling pathway|necroptotic signaling pathway|,RNA binding|double-stranded RNA binding|receptor activity|transmembrane signaling receptor activity|protein binding|,10,-0.1,0.137,10,-0.2,0.317,-0.1,0.384,-0.384,0.787,0,0,-1.3,1.7
ENSMUSG00000042659,ARRDC4,arrestin domain containing 4,endosome|plasma membrane|,positive regulation of ubiquitin-protein transferase activity|,molecular_function|,10,0.8,2.11,10,-1.3,0.817,0.3,0.38,0.38,0.788,0,0,-1.9,1.5
ENSMUSG00000027852,NRAS,neuroblastoma ras oncogene,intracellular|Golgi apparatus|plasma membrane|membrane|membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|Ras protein signal transduction|negative regulation of skeletal muscle tissue development|negative regulation of skeletal muscle tissue development|regulation of cell cycle|,nucleotide binding|GTPase activity|GTP binding|protein complex binding|,10,-0.2,0.748,10,0,0,-0.1,0.378,-0.378,0.789,0,0,-1.7,1.2
ENSMUSG00000040734,PPP1R13L,"protein phosphatase 1, regulatory (inhibitor) subunit 13 like",nucleus|cytoplasm|cell junction|,"negative regulation of transcription from RNA polymerase II promoter|cardiac right ventricle morphogenesis|ventricular cardiac muscle tissue development|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|post-embryonic development|embryonic camera-type eye development|multicellular organism growth|hair cycle|multicellular organismal homeostasis|cardiac muscle contraction|",protein binding|transcription factor binding|identical protein binding|,10,0.6,1.86,10,0,0,0.3,0.378,0.378,0.789,0,0,-1.2,1.8
ENSMUSG00000028402,MPDZ,multiple PDZ domain protein,cytoplasm|plasma membrane|tight junction|membrane|apical plasma membrane|apicolateral plasma membrane|cell junction|cytoplasmic vesicle|cell projection|neuron projection|Schmidt-Lanterman incisure|synapse|postsynaptic membrane|,cell adhesion|myelination|,protein binding|protein C-terminus binding|,10,-0.2,1.19,10,0.3,0.817,0.1,0.376,0.376,0.789,0,0,-1.1,1.6
ENSMUSG00000040265,DNM3,dynamin 3,cytoplasm|mitochondrion|cytoskeleton|microtubule|postsynaptic density|dendritic spine|perinuclear region of cytoplasm|,GTP catabolic process|endocytosis|synapse assembly|filopodium assembly|,nucleotide binding|GTPase activity|GTP binding|hydrolase activity|,10,-0.6,0.681,10,0.2,0.249,0.2,0.374,0.374,0.79,0,0,-1.5,1.5
ENSMUSG00000022949,CLIC6,chloride intracellular channel 6,cytoplasm|plasma membrane|membrane|integral component of membrane|chloride channel complex|extracellular vesicular exosome|,transport|ion transport|chloride transport|biological_process|regulation of ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|protein C-terminus binding|D2 dopamine receptor binding|D3 dopamine receptor binding|D4 dopamine receptor binding|protein homodimerization activity|,10,-0.3,1.1,10,0,0,0.1,0.368,0.368,0.792,0,0,-1.3,1.5
ENSMUSG00000055430,NAP1L5,nucleosome assembly protein 1-like 5,cellular_component|nucleus|,nucleosome assembly|biological_process|,molecular_function|,10,-0.6,1.27,10,-0.1,0.0401,-0.3,0.367,-0.367,0.792,0,0,-2,0.6
ENSMUSG00000026430,RASSF5,Ras association (RalGDS/AF-6) domain family member 5,nucleus|cytoplasm|cytoskeleton|microtubule|,apoptotic process|signal transduction|negative regulation of cell proliferation|positive regulation of protein ubiquitination|intracellular signal transduction|regulation of protein localization to nucleus|,protein binding|metal ion binding|,10,0.6,0.605,10,-0.1,0.123,0.2,0.367,0.367,0.792,0,0,-0.9,1.9
ENSMUSG00000047861,FOXI1,forkhead box I1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|inner ear morphogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.2,0.475,10,-0.3,1.22,-0.2,0.365,-0.365,0.792,0,0,-1.3,1.4
ENSMUSG00000053192,MLLT11,"myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11",intracellular|,"positive regulation of apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of mitochondrial depolarization|positive regulation of release of cytochrome c from mitochondria|apoptotic signaling pathway|extrinsic apoptotic signaling pathway|intrinsic apoptotic signaling pathway|",molecular_function|,10,0.3,0.511,10,0.1,0.213,0.1,0.365,0.365,0.792,0,0,-0.9,1.8
ENSMUSG00000020716,NF1,neurofibromatosis 1,intracellular|nucleus|cytoplasm|cytoplasm|postsynaptic density|membrane|axon|dendrite|intrinsic component of the cytoplasmic side of the plasma membrane|neuron projection|protein complex|,"MAPK cascade|osteoblast differentiation|metanephros development|response to hypoxia|liver development|negative regulation of endothelial cell proliferation|negative regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|regulation of cell-matrix adhesion|negative regulation of cell-matrix adhesion|negative regulation of protein kinase activity|negative regulation of protein kinase activity|cell communication|signal transduction|Ras protein signal transduction|Ras protein signal transduction|negative regulation of neuroblast proliferation|brain development|peripheral nervous system development|heart development|skeletal muscle tissue development|negative regulation of cell proliferation|negative regulation of cell proliferation|visual learning|visual learning|extrinsic apoptotic signaling pathway via death domain receptors|Schwann cell development|phosphatidylinositol 3-kinase signaling|negative regulation of angiogenesis|spinal cord development|forebrain astrocyte development|neural tube development|cerebral cortex development|myelination in peripheral nervous system|actin cytoskeleton organization|actin cytoskeleton organization|extracellular matrix organization|collagen fibril organization|adrenal gland development|negative regulation of cell migration|negative regulation of cell migration|negative regulation of cell migration|regulation of synaptic transmission, GABAergic|regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|negative regulation of Rac protein signal transduction|wound healing|regulation of cell proliferation|negative regulation of transcription factor import into nucleus|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of MAP kinase activity|negative regulation of MAP kinase activity|negative regulation of MAPK cascade|negative regulation of MAPK cascade|pigmentation|pigmentation|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|regulation of blood vessel endothelial cell migration|regulation of bone resorption|regulation of neuron differentiation|negative regulation of osteoclast differentiation|regulation of glial cell differentiation|positive regulation of adenylate cyclase activity|regulation of angiogenesis|regulation of angiogenesis|negative regulation of Ras protein signal transduction|negative regulation of Ras protein signal transduction|negative regulation of neurotransmitter secretion|negative regulation of neurotransmitter secretion|negative regulation of fibroblast proliferation|regulation of long-term neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|sympathetic nervous system development|camera-type eye morphogenesis|negative regulation of astrocyte differentiation|negative regulation of oligodendrocyte differentiation|smooth muscle tissue development|artery morphogenesis|forebrain morphogenesis|cognition|regulation of small GTPase mediated signal transduction|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|",GTPase activator activity|Ras GTPase activator activity|Ras GTPase activator activity|Ras GTPase activator activity|protein binding|microtubule binding|lipid binding|phosphatidylethanolamine binding|phosphatidylcholine binding|syndecan binding|,10,0,0,10,0.1,0.451,0.1,0.363,0.363,0.793,0,0,-1.3,1.6
ENSMUSG00000042712,WBP5,WW domain binding protein 5,cellular_component|,biological_process|,WW domain binding|,10,0,0,10,1.3,3.15,0.5,0.363,0.363,0.793,0,0,-0.3,2
ENSMUSG00000004791,PGF,placental growth factor,extracellular region|extracellular space|membrane|,angiogenesis|branching involved in ureteric bud morphogenesis|positive regulation of endothelial cell proliferation|sprouting angiogenesis|multicellular organismal development|positive regulation of cell proliferation|cell differentiation|positive regulation of angiogenesis|positive regulation of cell division|regulation of morphogenesis of a branching structure|,growth factor activity|protein homodimerization activity|protein heterodimerization activity|,10,-0.2,1.12,10,0,0,-0.1,0.355,-0.355,0.795,0,0,-1.6,1.4
ENSMUSG00000044827,TLR1,toll-like receptor 1,plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|Toll-like receptor 1-Toll-like receptor 2 protein complex|phagocytic vesicle|,microglial cell activation|toll-like receptor signaling pathway|immune system process|MyD88-dependent toll-like receptor signaling pathway|defense response|inflammatory response|immune response|signal transduction|activation of NF-kappaB-inducing kinase activity|response to bacterial lipoprotein|toll-like receptor 1 signaling pathway|macrophage activation|detection of triacyl bacterial lipopeptide|detection of triacyl bacterial lipopeptide|positive regulation of tumor necrosis factor biosynthetic process|innate immune response|positive regulation of interleukin-6 biosynthetic process|regulation of cytokine secretion|cellular response to triacyl bacterial lipopeptide|,transmembrane signaling receptor activity|triacyl lipopeptide binding|protein heterodimerization activity|lipopeptide binding|,10,0,0,10,-0.2,0.478,-0.2,0.351,-0.351,0.797,0,0,-1.5,1.4
ENSMUSG00000029084,CD38,CD38 antigen,nucleus|plasma membrane|cell surface|membrane|integral component of membrane|intracellular membrane-bounded organelle|,"response to hypoxia|positive regulation of cytosolic calcium ion concentration|metabolic process|response to hormone|positive regulation of cell growth|positive regulation of B cell proliferation|positive regulation of B cell proliferation|positive regulation of insulin secretion|response to hydroperoxide|response to drug|negative regulation of apoptotic process|negative regulation of bone resorption|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of vasoconstriction|B cell receptor signaling pathway|long term synaptic depression|","NAD+ nucleosidase activity|transferase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|phosphorus-oxygen lyase activity|NAD(P)+ nucleosidase activity|",10,-0.4,1.68,10,0.1,0.0256,-0.2,0.351,-0.351,0.797,0,0,-1.6,1.5
ENSMUSG00000008999,BMP7,bone morphogenetic protein 7,extracellular region|extracellular space|extracellular space|extracellular matrix|membrane-bounded vesicle|,"ossification|eye development|ureteric bud development|mesoderm formation|kidney development|multicellular organismal development|pattern specification process|axon guidance|salivary gland morphogenesis|negative regulation of cell proliferation|embryonic pattern specification|organ morphogenesis|positive regulation of peptidyl-threonine phosphorylation|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of cell death|cell differentiation|embryonic limb morphogenesis|embryonic limb morphogenesis|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|epithelial cell differentiation|positive regulation of heterotypic cell-cell adhesion|protein localization to nucleus|tube morphogenesis|growth|regulation of phosphorylation|negative regulation of phosphorylation|odontogenesis of dentin-containing tooth|positive regulation of apoptotic process|steroid hormone mediated signaling pathway|negative regulation of MAP kinase activity|positive regulation of cell differentiation|negative regulation of neuron differentiation|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of osteoblast differentiation|negative regulation of Notch signaling pathway|negative regulation of cell cycle|negative regulation of mitosis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|cell development|camera-type eye morphogenesis|embryonic camera-type eye morphogenesis|anatomical structure formation involved in morphogenesis|branching morphogenesis of an epithelial tube|mesenchymal cell differentiation|neuron projection morphogenesis|neuron projection morphogenesis|negative regulation of neurogenesis|cartilage development|embryonic skeletal joint morphogenesis|embryonic skeletal joint morphogenesis|regulation of pathway-restricted SMAD protein phosphorylation|SMAD protein signal transduction|branching involved in salivary gland morphogenesis|mesenchyme development|negative regulation of cell death|negative regulation of prostatic bud formation|regulation of branching involved in prostate gland morphogenesis|monocyte aggregation|negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis|negative regulation of glomerular mesangial cell proliferation|metanephric mesenchyme morphogenesis|nephrogenic mesenchyme morphogenesis|metanephric mesenchymal cell proliferation involved in metanephros development|positive regulation of dendrite development|positive regulation of hyaluranon cable assembly|",cytokine activity|protein binding|growth factor activity|heparin binding|BMP receptor binding|,10,-0.3,1.65,10,0,0,-0.1,0.347,-0.347,0.798,0,0,-1.8,1.1
ENSMUSG00000020135,APC2,adenomatosis polyposis coli 2,cytoplasm|Golgi apparatus|cytoplasmic microtubule|actin filament|microtubule cytoskeleton|catenin complex|lamellipodium membrane|perinuclear region of cytoplasm|,negative regulation of catenin import into nucleus|negative regulation of canonical Wnt signaling pathway|,beta-catenin binding|,10,0.1,0.32,10,0.4,0.534,0.2,0.345,0.345,0.798,0,0,-0.9,1.8
ENSMUSG00000016128,STARD13,StAR-related lipid transfer (START) domain containing 13,intracellular|cytoplasm|mitochondrion|lipid particle|membrane|,cell cycle|signal transduction|,GTPase activator activity|lipid binding|,10,-0.1,0.271,10,-0.1,0.107,-0.1,0.345,-0.345,0.798,0,0,-1.7,1.2
ENSMUSG00000002550,UCK1,uridine-cytidine kinase 1,None,metabolic process|nucleotide biosynthetic process|phosphorylation|,nucleotide binding|uridine kinase activity|ATP binding|kinase activity|transferase activity|nucleoside kinase activity|,10,0.1,0.388,10,-0.2,0.43,-0.1,0.342,-0.342,0.799,0,0,-1.3,1.6
ENSMUSG00000030200,BCL2L14,BCL2-like 14 (apoptosis facilitator),cytoplasm|cytosol|intracellular organelle|,apoptotic process|apoptotic process|regulation of apoptotic process|positive regulation of extrinsic apoptotic signaling pathway|,protein binding|protein kinase binding|,10,-0.4,1.97,10,0,0,-0.2,0.342,-0.342,0.799,0,0,-1.9,0.9
ENSMUSG00000027765,P2RY1,"purinergic receptor P2Y, G-protein coupled 1",mitochondrion|plasma membrane|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|dendrite|cell body|postsynaptic membrane|neuronal postsynaptic density|,positive regulation of protein phosphorylation|adenosine receptor signaling pathway|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|glial cell migration|response to mechanical stimulus|regulation of receptor activity|negative regulation of norepinephrine secretion|sensory perception of pain|signal transduction involved in regulation of gene expression|platelet activation|positive regulation of inositol trisphosphate biosynthetic process|G-protein coupled purinergic nucleotide receptor signaling pathway|regulation of vasodilation|eating behavior|positive regulation of ion transport|positive regulation of ion transport|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hormone secretion|negative regulation of binding|positive regulation of penile erection|positive regulation of ERK1 and ERK2 cascade|protein localization to plasma membrane|relaxation of muscle|,signal transducer activity|G-protein coupled receptor activity|ATP binding|A1 adenosine receptor binding|ADP binding|G-protein coupled purinergic nucleotide receptor activity|ATP-activated nucleotide receptor activity|ADP-activated nucleotide receptor activity|protein heterodimerization activity|scaffold protein binding|,10,-0.2,0.0781,10,-0.1,0.301,-0.2,0.341,-0.341,0.799,0,0,-1.5,1.4
ENSMUSG00000021702,THBS4,thrombospondin 4,extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|extracellular space|endoplasmic reticulum|sarcoplasmic reticulum|extracellular matrix|neuromuscular junction|,positive regulation of endothelial cell proliferation|response to unfolded protein|cell adhesion|nervous system development|regulation of tissue remodeling|response to endoplasmic reticulum stress|behavioral response to pain|behavioral response to pain|tissue remodeling|neuron projection morphogenesis|positive regulation of peptidyl-tyrosine phosphorylation|protein homooligomerization|myoblast migration|positive regulation of cell division|endothelial cell-cell adhesion|positive regulation of neutrophil chemotaxis|,fibronectin binding|integrin binding|calcium ion binding|protein binding|collagen binding|growth factor activity|heparin binding|laminin-1 binding|,10,-0.3,1.19,10,0,0,-0.2,0.34,-0.34,0.8,0,0,-1.7,1.1
ENSMUSG00000028917,PLEKHM2,"pleckstrin homology domain containing, family M (with RUN domain) member 2",cellular_component|cytoplasm|,Golgi organization|,kinesin binding|,10,-0.2,0.304,10,-0.1,0.127,-0.2,0.338,-0.338,0.8,0,0,-1.6,1.2
ENSMUSG00000035799,TWIST1,twist basic helix-loop-helix transcription factor 1,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|ossification|osteoblast differentiation|in utero embryonic development|neuron migration|neural tube closure|aortic valve morphogenesis|aortic valve morphogenesis|mitral valve morphogenesis|endocardial cushion morphogenesis|cardiac neural crest cell migration involved in outflow tract morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|muscle organ development|positive regulation of gene expression|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|negative regulation of phosphatidylinositol 3-kinase signaling|cell differentiation|embryonic limb morphogenesis|regulation of bone mineralization|positive regulation of fatty acid beta-oxidation|negative regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|negative regulation of histone phosphorylation|negative regulation of histone acetylation|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|hindlimb morphogenesis|negative regulation of peroxisome proliferator activated receptor signaling pathway|embryonic digit morphogenesis|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of molecular function|negative regulation of cell differentiation|negative regulation of osteoblast differentiation|negative regulation of osteoblast differentiation|negative regulation of striated muscle tissue development|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|negative regulation of skeletal muscle tissue development|embryonic cranial skeleton morphogenesis|embryonic cranial skeleton morphogenesis|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|positive regulation of epithelial cell proliferation|cranial suture morphogenesis|embryonic camera-type eye formation|eyelid development in camera-type eye|cardiac neural crest cell development involved in outflow tract morphogenesis|cellular response to hypoxia|cellular response to hypoxia|positive regulation of monocyte chemotactic protein-1 production|positive regulation of cell motility|positive regulation of cell motility|negative regulation of oxidative phosphorylation uncoupler activity|positive regulation of transcription regulatory region DNA binding|negative regulation of cellular senescence|positive regulation of interleukin-6 secretion|negative regulation of double-strand break repair|cell proliferation involved in heart valve development|cell proliferation involved in heart valve development|positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|transcription factor binding|protein domain specific binding|protein homodimerization activity|bHLH transcription factor binding|protein heterodimerization activity|protein dimerization activity|E-box binding|E-box binding|E-box binding|,10,0.2,0.519,10,-0.2,0.469,0.2,0.335,0.335,0.801,0,0,-1.3,1.5
ENSMUSG00000024921,SMARCA2,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2",nuclear chromatin|nucleus|nucleus|SWI/SNF complex|SWI/SNF complex|intracellular membrane-bounded organelle|intermediate filament cytoskeleton|npBAF complex|nBAF complex|,"chromatin organization|nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|nervous system development|negative regulation of cell proliferation|negative regulation of cell growth|aortic smooth muscle cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|","nucleotide binding|RNA polymerase II transcription coactivator activity|DNA binding|helicase activity|protein binding|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|histone binding|transcription regulatory region DNA binding|",10,0,0,10,1.3,2.4,-0.1,0.334,-0.334,0.801,0,0,-0.7,2
ENSMUSG00000020686,GAS2L2,growth arrest-specific 2 like 2,stress fiber|cytoplasm|cytoskeleton|microtubule|,microtubule bundle formation|negative regulation of microtubule depolymerization|cell cycle arrest|,microtubule binding|cytoskeletal adaptor activity|actin filament binding|,10,-0.5,1.04,10,0.1,0.0887,-0.1,0.331,-0.331,0.802,0,0,-1.8,1
ENSMUSG00000048922,CDCA2,cell division cycle associated 2,nucleus|chromosome|cytoplasm|,cell cycle|chromosome segregation|mitotic nuclear division|positive regulation of protein dephosphorylation|cell division|,molecular_function|,9,0,0,9,0.2,0.478,0.1,0.33,0.33,0.802,0,0,-1.1,1.8
ENSMUSG00000074340,OVGP1,oviductal glycoprotein 1,cytoplasmic vesicle|egg coat|perivitelline space|,carbohydrate metabolic process|chitin catabolic process|single fertilization|negative regulation of binding of sperm to zona pellucida|negative regulation of binding of sperm to zona pellucida|,"hydrolase activity, hydrolyzing O-glycosyl compounds|chitinase activity|",10,-0.1,0.213,10,-0.1,0.146,-0.1,0.328,-0.328,0.803,0,0,-1.3,1.6
ENSMUSG00000006782,CNP,"2',3'-cyclic nucleotide 3' phosphodiesterase",extracellular space|nucleus|cytoplasm|mitochondrial outer membrane|mitochondrial inner membrane|microtubule|plasma membrane|microvillus|membrane|membrane|pseudopodium|myelin sheath abaxonal region|myelin sheath adaxonal region|cell projection|perinuclear region of cytoplasm|extracellular vesicular exosome|,microtubule cytoskeleton organization|axonogenesis|adult locomotory behavior|cyclic nucleotide catabolic process|response to toxic substance|regulation of mitochondrial membrane permeability|oligodendrocyte differentiation|,"RNA binding|catalytic activity|2',3'-cyclic-nucleotide 3'-phosphodiesterase activity|2',3'-cyclic-nucleotide 3'-phosphodiesterase activity|hydrolase activity|cyclic nucleotide binding|",10,0,0,10,0.7,2.22,0.1,0.326,0.326,0.804,0,0,-0.5,2
ENSMUSG00000047751,UTF1,undifferentiated embryonic cell transcription factor 1,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",transcription coactivator activity|transcription coactivator activity|protein binding|HMG box domain binding|,10,0,0,10,0.1,0.393,0.2,0.324,0.324,0.804,0,0,-0.9,1.9
ENSMUSG00000021400,WRNIP1,Werner helicase interacting protein 1,nucleus|nucleus|membrane|perinuclear region of cytoplasm|,DNA synthesis involved in DNA repair|ATP catabolic process|DNA replication|DNA repair|cellular response to DNA damage stimulus|regulation of DNA-dependent DNA replication initiation|,nucleotide binding|DNA binding|protein binding|ATP binding|hydrolase activity|ATPase activity|identical protein binding|,8,-0.4,2.08,8,0,0,-0.3,0.324,-0.324,0.804,0,0,-1.8,1.2
ENSMUSG00000024900,CPT1A,"carnitine palmitoyltransferase 1a, liver",mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|intracellular membrane-bounded organelle|,long-chain fatty acid metabolic process|glucose metabolic process|lipid metabolic process|fatty acid metabolic process|triglyceride metabolic process|transport|carnitine metabolic process|positive regulation of fatty acid beta-oxidation|eating behavior|regulation of fatty acid oxidation|regulation of insulin secretion|protein homooligomerization|,"carnitine O-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|identical protein binding|",10,0,0,10,0.4,1.06,0.2,0.319,0.319,0.805,0,0,-1.1,1.8
ENSMUSG00000050953,GJA1,"gap junction protein, alpha 1",cytoplasm|cytoplasm|mitochondrial outer membrane|lysosome|endosome|early endosome|late endosome|multivesicular body|Golgi apparatus|Golgi apparatus|cytosol|intermediate filament|plasma membrane|plasma membrane|cell-cell junction|cell-cell junction|fascia adherens|fascia adherens|gap junction|gap junction|connexon complex|intercalated disc|intercalated disc|membrane|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|cell junction|contractile fiber|membrane raft|extracellular vesicular exosome|,osteoblast differentiation|in utero embryonic development|neuron migration|negative regulation of endothelial cell proliferation|heart looping|epithelial cell maturation|lens development in camera-type eye|chronic inflammatory response|positive regulation of glomerular filtration|atrial ventricular junction remodeling|epicardial cell to mesenchymal cell transition|apoptotic process|cell communication|signal transduction|positive regulation of cytosolic calcium ion concentration|cell-cell signaling|cell-cell signaling|heart development|adult heart development|regulation of heart contraction|negative regulation of cell proliferation|response to pH|vascular transport|positive regulation of gene expression|negative regulation of gene expression|cell communication by chemical coupling|cell communication by electrical coupling|cell communication by electrical coupling|positive regulation of cell communication by chemical coupling|ATP transport|regulation of bone mineralization|positive regulation of insulin secretion|embryonic heart tube development|embryonic digit morphogenesis|positive regulation of I-kappaB kinase/NF-kappaB signaling|skeletal muscle tissue regeneration|cell-cell junction organization|positive regulation of osteoblast differentiation|positive regulation of protein catabolic process|positive regulation of striated muscle tissue development|positive regulation of vasoconstriction|positive regulation of vasodilation|regulation of bone remodeling|blood vessel morphogenesis|neuron projection morphogenesis|protein oligomerization|regulation of calcium ion transport|transmembrane transport|transmembrane transport|negative regulation of cardiac muscle cell proliferation|milk ejection|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of blood vessel remodeling|regulation of atrial cardiac muscle cell membrane depolarization|regulation of ventricular cardiac muscle cell membrane depolarization|regulation of ventricular cardiac muscle cell membrane depolarization|negative regulation of wound healing|cardiac conduction|establishment of epithelial cell polarity|negative regulation of DNA biosynthetic process|regulation of tight junction assembly|positive regulation of behavioral fear response|,signal transducer activity|receptor binding|gap junction channel activity|gap junction channel activity|protein binding|SH3 domain binding|protein domain specific binding|transmembrane transporter activity|PDZ domain binding|beta-tubulin binding|connexin binding|scaffold protein binding|,10,0,0,10,1.3,2.82,1.2,0.316,0.316,0.806,0,0,-0.2,2
ENSMUSG00000026547,TAGLN2,transgelin 2,extracellular vesicular exosome|,epithelial cell differentiation|,None,10,0.2,0.299,10,0.1,0.091,0.1,0.31,0.31,0.808,0,0,-0.9,1.8
ENSMUSG00000062859,TCP11,t-complex protein 11,membrane|integral component of membrane|,multicellular organismal development|spermatogenesis|cell differentiation|,None,10,-0.1,0.0958,10,0.3,0.895,0.2,0.31,0.31,0.808,0,0,-1,1.8
ENSMUSG00000024811,TNKS2,"tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2","pericentriolar material|chromosome, telomeric region|nucleus|nuclear envelope|chromosome|cytoplasm|Golgi apparatus|membrane|perinuclear region of cytoplasm|","protein polyubiquitination|telomere maintenance|protein ADP-ribosylation|Wnt signaling pathway|multicellular organism growth|regulation of multicellular organism growth|protein localization to chromosome, telomeric region|protein auto-ADP-ribosylation|positive regulation of canonical Wnt signaling pathway|","NAD+ ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|enzyme binding|metal ion binding|",10,0.2,0.393,10,0.1,0.0786,0.1,0.308,0.308,0.809,0,0,-1.7,1.3
ENSMUSG00000030782,TGFB1I1,transforming growth factor beta 1 induced transcript 1,intracellular|nucleus|cytoplasm|cytoskeleton|focal adhesion|cell junction|extracellular matrix|,"response to heat|positive regulation of epithelial to mesenchymal transition|Wnt signaling pathway|morphogenesis of embryonic epithelium|cell differentiation|positive regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|ubiquitin-dependent SMAD protein catabolic process|epithelial cell differentiation|cell fate commitment|negative regulation of fat cell differentiation|positive regulation of transcription, DNA-templated|",transcription coactivator activity|protein binding|zinc ion binding|metal ion binding|Roundabout binding|androgen receptor binding|I-SMAD binding|,10,0,0,10,0.4,0.778,0.2,0.308,0.308,0.809,0,0,-0.9,1.8
ENSMUSG00000028211,TRP53INP1,transformation related protein 53 inducible nuclear protein 1,nucleus|nucleus|cytoplasm|autophagic vacuole|cytosol|cytoplasmic vesicle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|autophagy|apoptotic process|cell cycle arrest|negative regulation of cell proliferation|response to heat|positive regulation of autophagy|negative regulation of cell migration|cellular response to UV|positive regulation of apoptotic process|positive regulation of transcription, DNA-templated|autophagic cell death|cellular response to ethanol|cellular response to hydroperoxide|cellular response to methyl methanesulfonate|positive regulation of apoptotic signaling pathway|",antioxidant activity|,10,0.4,1.68,10,-0.2,0.563,-0.2,0.308,-0.308,0.809,0,0,-1.3,1.5
ENSMUSG00000034456,UROC1,urocanase domain containing 1,cytosol|,histidine metabolic process|histidine catabolic process|,urocanate hydratase activity|lyase activity|,10,0,0,10,-0.4,1.26,-0.2,0.305,-0.305,0.809,0,0,-1.8,1
ENSMUSG00000062410,HSD3B3,"hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3",mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial intermembrane space|endoplasmic reticulum|membrane|integral component of membrane|,steroid biosynthetic process|metabolic process|oxidation-reduction process|,"catalytic activity|3-beta-hydroxy-delta5-steroid dehydrogenase activity|steroid delta-isomerase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|isomerase activity|",10,0,0,10,-0.2,0.889,-0.1,0.304,-0.304,0.81,0,0,-1.6,1.3
ENSMUSG00000001128,CFP,complement factor properdin,extracellular region|extracellular matrix|,"immune system process|complement activation, alternative pathway|innate immune response|",None,10,0.2,0.567,10,-0.5,1.31,-0.5,0.298,-0.298,0.812,0,0,-1.9,1
ENSMUSG00000013698,PEA15A,phosphoprotein enriched in astrocytes 15A,intracellular|cytoplasm|microtubule associated complex|,transport|apoptotic process|carbohydrate transport|intracellular signal transduction|regulation of apoptotic process|negative regulation of glucose import|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|,protein kinase C binding|,9,0.5,0.483,9,0.1,0.05,0.1,0.297,0.297,0.812,0,0,-1.3,1.7
ENSMUSG00000021301,HECW1,"HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1",nucleus|cytoplasm|,protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.941,9,0,0,-0.1,0.297,-0.297,0.812,0,0,-1.5,1.5
ENSMUSG00000000440,PPARG,peroxisome proliferator activated receptor gamma,nucleus|nucleus|cytoplasm|cytosol|cytosol|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of cytokine production|placenta development|negative regulation of acute inflammatory response|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|activation of cysteine-type endopeptidase activity involved in apoptotic process|inflammatory response|signal transduction|regulation of blood pressure|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of macrophage derived foam cell differentiation|negative regulation of receptor biosynthetic process|negative regulation of cholesterol storage|negative regulation of sequestering of triglyceride|long-chain fatty acid transport|regulation of lipid metabolic process|fatty acid oxidation|monocyte differentiation|negative regulation of cell growth|intracellular receptor signaling pathway|epithelial cell differentiation|response to retinoic acid|response to retinoic acid|cellular response to insulin stimulus|negative regulation of collagen biosynthetic process|response to lipid|peroxisome proliferator activated receptor signaling pathway|glucose homeostasis|lipoprotein transport|positive regulation of apoptotic process|steroid hormone mediated signaling pathway|cell fate commitment|fat cell differentiation|fat cell differentiation|regulation of fat cell differentiation|regulation of fat cell differentiation|regulation of fat cell differentiation|positive regulation of fat cell differentiation|positive regulation of fat cell differentiation|positive regulation of fat cell differentiation|low-density lipoprotein particle receptor biosynthetic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fatty acid oxidation|cell maturation|negative regulation of smooth muscle cell proliferation|positive regulation of oligodendrocyte differentiation|white fat cell differentiation|brown fat cell differentiation|positive regulation of sequence-specific DNA binding transcription factor activity|negative regulation of telomerase activity|response to low-density lipoprotein particle|positive regulation of phagocytosis, engulfment|negative regulation of interferon-gamma-mediated signaling pathway|regulation of transcription involved in cell fate commitment|cellular response to lithium ion|cellular response to organic cyclic compound|negative regulation of peptide hormone secretion|negative regulation of cellular response to insulin stimulus|negative regulation of pancreatic stellate cell proliferation|",RNA polymerase II regulatory region DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|transcription factor binding|drug binding|zinc ion binding|enzyme binding|protein phosphatase binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity|activating transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|retinoid X receptor binding|arachidonic acid binding|,10,0,0,10,0.3,1.35,0.1,0.296,0.296,0.812,0,0,-1.1,1.7
ENSMUSG00000029014,DNAJC2,"DnaJ (Hsp40) homolog, subfamily C, member 2",nucleus|cytoplasm|cytosol|nuclear membrane|,"DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|negative regulation of cell growth|positive regulation of transcription, DNA-templated|negative regulation of DNA biosynthetic process|",DNA binding|chromatin binding|protein binding|Hsp70 protein binding|histone binding|ubiquitin binding|poly(A) RNA binding|,9,-0.2,1.18,10,0.6,0.792,-0.1,0.294,-0.294,0.813,0,0,-1.1,1.8
ENSMUSG00000026259,NGEF,neuronal guanine nucleotide exchange factor,cytoplasm|membrane|cell projection|,multicellular organismal development|nervous system development|cellular process|cell differentiation|regulation of Rho protein signal transduction|regulation of GTPase activity|regulation of GTPase activity|ephrin receptor signaling pathway|ephrin receptor signaling pathway|negative regulation of dendritic spine morphogenesis|negative regulation of dendritic spine morphogenesis|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|ephrin receptor binding|ephrin receptor binding|,10,-0.3,0.609,10,0.3,0.643,0.2,0.293,0.293,0.813,0,0,-0.9,1.9
ENSMUSG00000031451,GAS6,growth arrest specific 6,extracellular region|extracellular space|extracellular space|intracellular|intracellular|cytoplasm|extracellular vesicular exosome|,"neuron migration|positive regulation of protein phosphorylation|positive regulation of cytokine-mediated signaling pathway|positive regulation of glomerular filtration|protein phosphorylation|phagocytosis|signal transduction|signal transduction|enzyme linked receptor protein signaling pathway|blood coagulation|cellular response to starvation|positive regulation of gene expression|negative regulation of tumor necrosis factor-mediated signaling pathway|macrophage cytokine production|peptidyl-serine phosphorylation|fusion of virus membrane with host plasma membrane|viral genome replication|cell-substrate adhesion|positive regulation of TOR signaling|activation of protein kinase B activity|negative regulation of interferon-gamma production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|positive regulation of natural killer cell differentiation|positive regulation of peptidyl-serine phosphorylation|negative regulation of protein import into nucleus, translocation|regulation of ion transmembrane transport|cellular response to interferon-alpha|cellular response to drug|B cell chemotaxis|regulation of growth|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|apoptotic cell clearance|apoptotic cell clearance|negative regulation of sequence-specific DNA binding transcription factor activity|protein kinase B signaling|protein kinase B signaling|protein kinase B signaling|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|viral entry into host cell|receptor-mediated virion attachment to host cell|positive regulation of protein export from nucleus|positive regulation of fibroblast proliferation|negative regulation of interleukin-1 secretion|positive regulation of phagocytosis|positive regulation of protein kinase B signaling|positive regulation of protein tyrosine kinase activity|negative regulation of biomineral tissue development|positive regulation of ERK1 and ERK2 cascade|calcium ion transmembrane transport|cellular response to vitamin K|cellular response to glucose stimulus|cellular response to growth factor stimulus|cellular response to growth factor stimulus|protein targeting to plasma membrane|hematopoietic stem cell migration to bone marrow|negative regulation of oligodendrocyte apoptotic process|negative regulation of interleukin-6 secretion|negative regulation of fibroblast apoptotic process|positive regulation of receptor activity|negative regulation of endothelial cell apoptotic process|positive regulation of dendritic cell chemotaxis|negative regulation of dendritic cell apoptotic process|","phosphatidylserine binding|receptor binding|voltage-gated calcium channel activity|calcium ion binding|protein tyrosine kinase activator activity|receptor tyrosine kinase binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|metal ion binding|receptor agonist activity|receptor agonist activity|binding, bridging|",10,-0.1,0.0962,10,-0.2,0.249,-0.1,0.293,-0.293,0.813,0,0,-1.6,1.3
ENSMUSG00000003271,SULT2B1,"sulfotransferase family, cytosolic, 2B, member 1",cytoplasm|endoplasmic reticulum|intracellular membrane-bounded organelle|,sulfate assimilation|lipid metabolic process|steroid metabolic process|,alcohol sulfotransferase activity|sulfotransferase activity|transferase activity|steroid sulfotransferase activity|,10,-0.2,0.215,10,-0.3,0.129,-0.2,0.292,-0.292,0.814,0,0,-1.7,1.2
ENSMUSG00000038067,CSF3,colony stimulating factor 3 (granulocyte),extracellular region|extracellular space|,immune response|positive regulation of cell proliferation|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of actin filament polymerization|granulocyte differentiation|positive regulation of protein binding|positive regulation of peptidyl-serine phosphorylation|positive regulation of transcription factor import into nucleus|positive regulation of transcription from RNA polymerase II promoter|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of protein kinase B signaling|cellular response to cytokine stimulus|negative regulation of neuron death|positive regulation of actin cytoskeleton reorganization|,cytokine activity|cytokine activity|growth factor activity|enzyme binding|,10,0.3,0.645,10,0,0,0.2,0.287,0.287,0.815,0,0,-0.9,1.8
ENSMUSG00000027347,RASGRP1,RAS guanyl releasing protein 1,intracellular|cell|cytoplasm|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|mast cell granule|,cytokine production|inflammatory response to antigenic stimulus|small GTPase mediated signal transduction|regulation of phosphatidylinositol 3-kinase signaling|cell differentiation|secretory granule localization|activation of Ras GTPase activity|activation of Rho GTPase activity|intracellular signal transduction|mast cell degranulation|vesicle transport along microtubule|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|calcium ion binding|metal ion binding|,10,0,0,10,-0.2,0.805,-0.1,0.287,-0.287,0.815,0,0,-1.7,1.2
ENSMUSG00000032965,IFT57,intraflagellar transport 57,intracellular|cell|cytoplasm|Golgi apparatus|centrosome|cytoskeleton|cilium|cilium|intraciliary transport particle B|photoreceptor connecting cilium|ciliary basal body|ciliary basal body|cell projection|dendrite terminus|primary cilium|,"neural tube closure|heart looping|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|smoothened signaling pathway|intraciliary transport|intraciliary transport|cilium assembly|regulation of apoptotic process|negative regulation of epithelial cell proliferation|cilium morphogenesis|left/right pattern formation|",DNA binding|protein binding|,10,-0.2,0.0569,10,-0.2,0.256,-0.2,0.286,-0.286,0.815,0,0,-1.8,1
ENSMUSG00000031465,ANGPT2,angiopoietin 2,extracellular region|extracellular space|nucleus|plasma membrane|cell projection|,angiogenesis|blood vessel remodeling|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|endoderm development|negative regulation of cell-substrate adhesion|negative regulation of angiogenesis|hemopoiesis|cell differentiation|negative regulation of blood vessel endothelial cell migration|regulation of angiogenesis|positive regulation of angiogenesis|Tie signaling pathway|Tie signaling pathway|blood vessel morphogenesis|negative regulation of positive chemotaxis|glomerulus vasculature development|,vascular endothelial growth factor receptor binding|protein binding|receptor tyrosine kinase binding|metal ion binding|,10,-0.4,1.31,10,0.1,0.093,0.1,0.285,0.285,0.816,0,0,-1.5,1.4
ENSMUSG00000042474,FAIM3,Fas apoptotic inhibitory molecule 3,membrane|integral component of membrane|,immune system process|,None,10,0,0,10,0.2,0.516,0.2,0.284,0.284,0.816,0,0,-0.7,2
ENSMUSG00000020176,GRB10,growth factor receptor bound protein 10,cytoplasm|cytosol|,signal transduction|insulin receptor signaling pathway|positive regulation of signal transduction|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|positive regulation of vascular endothelial growth factor receptor signaling pathway|response to insulin|negative regulation of phosphorylation|positive regulation of phosphorylation|negative regulation of glycogen biosynthetic process|negative regulation of glycogen biosynthetic process|negative regulation of glucose import|negative regulation of insulin receptor signaling pathway|insulin-like growth factor receptor signaling pathway|,phosphotyrosine binding|SH3/SH2 adaptor activity|SH3/SH2 adaptor activity|insulin receptor binding|insulin receptor binding|protein binding|,10,-0.2,0.265,10,0.4,1.96,0.3,0.282,0.282,0.816,0,0,-1.7,1.3
ENSMUSG00000027678,NCOA3,nuclear receptor coactivator 3,nucleus|nucleus|cytoplasm|Golgi apparatus|perinuclear region of cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|positive regulation of gene expression|histone acetylation|positive regulation of cell growth|positive regulation of intracellular steroid hormone receptor signaling pathway|positive regulation of intracellular estrogen receptor signaling pathway|multicellular organism growth|negative regulation of apoptotic process|positive regulation of keratinocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|developmental growth|positive regulation of sequence-specific DNA binding transcription factor activity|vagina development|labyrinthine layer morphogenesis|mammary gland branching involved in thelarche|regulation of RNA biosynthetic process|","RNA polymerase II regulatory region DNA binding|DNA binding|chromatin binding|transcription coactivator activity|histone acetyltransferase activity|signal transducer activity|transferase activity|transferase activity, transferring acyl groups|ligand-dependent nuclear receptor binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|protein complex binding|nuclear hormone receptor binding|peroxisome proliferator activated receptor binding|protein dimerization activity|protein N-terminus binding|androgen receptor binding|",10,0,0,10,-0.3,0.664,-0.2,0.276,-0.276,0.818,0,0,-1.8,1
ENSMUSG00000063810,ALMS1,Alstrom syndrome 1,intracellular|cytoplasm|centrosome|centriole|ciliary basal body|,cellular glucose homeostasis|establishment of planar polarity|lipid metabolic process|spermatid development|sensory perception of sound|endosomal transport|calcium-mediated signaling|ovulation|negative regulation of multicellular organism growth|cilium assembly|glucose homeostasis|cholesterol homeostasis|negative regulation of apoptotic process|fat cell differentiation|regulation of fat cell differentiation|retinal rod cell development|epithelial cell proliferation|regulation of stress fiber assembly|inner ear receptor stereocilium organization|,alpha-actinin binding|,10,0,0,10,1.1,1.69,1,0.276,0.276,0.818,0,0,-0.9,2
ENSMUSG00000089682,BCL2L2,BCL2-like 2,cytoplasm|mitochondrion|mitochondrial outer membrane|cytosol|membrane|mitochondrial membrane|extracellular vesicular exosome|,apoptotic process|intrinsic apoptotic signaling pathway in response to DNA damage|regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|Sertoli cell proliferation|extrinsic apoptotic signaling pathway in absence of ligand|negative regulation of intrinsic apoptotic signaling pathway|,protein binding|protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|BH domain binding|,10,0.2,0.106,10,-0.1,0.362,-0.1,0.271,-0.271,0.82,0,0,-1.5,1.4
ENSMUSG00000060803,GSTP1,"glutathione S-transferase, pi 1",extracellular space|intracellular|intracellular|nucleus|cytoplasm|mitochondrion|cytosol|plasma membrane|protein complex|extracellular vesicular exosome|TRAF2-GSTP1 complex|,response to reactive oxygen species|negative regulation of acute inflammatory response|glutathione metabolic process|metabolic process|negative regulation of biosynthetic process|negative regulation of interleukin-1 beta production|negative regulation of tumor necrosis factor production|regulation of stress-activated MAPK cascade|negative regulation of stress-activated MAPK cascade|positive regulation of superoxide anion generation|common myeloid progenitor cell proliferation|negative regulation of apoptotic process|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of JUN kinase activity|negative regulation of JUN kinase activity|negative regulation of fibroblast proliferation|negative regulation of nitric-oxide synthase biosynthetic process|regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 and ERK2 cascade|negative regulation of leukocyte proliferation|cellular response to lipopolysaccharide|negative regulation of monocyte chemotactic protein-1 production|negative regulation of neutrophil aggregation|negative regulation of peroxidase activity|,glutathione transferase activity|glutathione transferase activity|drug binding|JUN kinase binding|transferase activity|kinase regulator activity|S-nitrosoglutathione binding|dinitrosyl-iron complex binding|glutathione binding|,10,-0.1,0.024,10,0.2,0.889,0.1,0.27,0.27,0.82,0,0,-1,1.8
ENSMUSG00000022285,YWHAZ,"tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide",extracellular space|nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|postsynaptic density|cell leading edge|mast cell granule|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|blood microparticle|,histamine secretion by mast cell|protein targeting|protein targeting to mitochondrion|regulation of cell death|response to drug|,protein binding|transcription factor binding|protein kinase binding|protein domain specific binding|protein complex binding|identical protein binding|poly(A) RNA binding|,10,0,0,9,0.3,0.9,0.1,0.269,0.269,0.82,0,0,-1.2,1.7
ENSMUSG00000042292,MKL1,MKL (megakaryoblastic leukemia)/myocardin-like 1,nucleus|nucleus|cytoplasm|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|positive regulation of transcription via serum response element binding|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|smooth muscle cell differentiation|negative regulation of apoptotic signaling pathway|",transcription regulatory region sequence-specific DNA binding|nucleic acid binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|actin binding|actin binding|actin monomer binding|protein binding|leucine zipper domain binding|,10,-0.1,0.257,10,-0.1,0.0344,-0.1,0.266,-0.266,0.821,0,0,-1.8,1.1
ENSMUSG00000030035,WBP1,WW domain binding protein 1,cellular_component|,biological_process|,protein binding|WW domain binding|WW domain binding|,10,0,0,10,-0.2,0.59,-0.2,0.265,-0.265,0.822,0,0,-1.9,0.8
ENSMUSG00000090171,UGT1A2,"UDP glucuronosyltransferase 1 family, polypeptide A2",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,metabolic process|cellular glucuronidation|flavonoid glucuronidation|xenobiotic glucuronidation|,"retinoic acid binding|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|enzyme binding|protein homodimerization activity|protein heterodimerization activity|",5,-0.2,0.522,5,0.1,0.124,0.1,0.264,0.264,0.822,0,0,-1.6,1.8
ENSMUSG00000026821,RALGDS,ral guanine nucleotide dissociation stimulator,intracellular|,signal transduction|small GTPase mediated signal transduction|regulation of catalytic activity|regulation of small GTPase mediated signal transduction|,small GTPase regulator activity|guanyl-nucleotide exchange factor activity|protein binding|,10,0,0,10,1.3,1.99,-0.1,0.261,-0.261,0.823,0,0,-0.9,2
ENSMUSG00000029201,UGDH,UDP-glucose dehydrogenase,nucleus|cytosol|,gastrulation with mouth forming second|metabolic process|oxidation-reduction process|,"catalytic activity|UDP-glucose 6-dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|NAD binding|",10,-1.1,1.81,10,0.2,0.616,-1,0.261,-0.261,0.823,0,0,-2,1.1
ENSMUSG00000028909,PTPRU,"protein tyrosine phosphatase, receptor type, U",plasma membrane|cell-cell junction|membrane|integral component of membrane|cell junction|,protein dephosphorylation|cell adhesion|negative regulation of cell proliferation|dephosphorylation|single organismal cell-cell adhesion|cell differentiation|negative regulation of cell migration|homotypic cell-cell adhesion|protein localization to cell surface|peptidyl-tyrosine dephosphorylation|canonical Wnt signaling pathway|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|beta-catenin binding|beta-catenin binding|hydrolase activity|phosphatase activity|,10,0,0,10,-0.3,0.882,-0.1,0.257,-0.257,0.824,0,0,-1.9,0.9
ENSMUSG00000035274,TPBG,trophoblast glycoprotein,cytoplasm|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,None,None,10,-0.1,0.109,10,-0.1,0.169,-0.1,0.254,-0.254,0.825,0,0,-1.6,1.3
ENSMUSG00000044068,ZRSR1,"zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1",nucleus|virion|viral nucleocapsid|ribonucleoprotein complex|,None,nucleotide binding|nucleic acid binding|RNA binding|metal ion binding|,10,-0.2,0.689,10,0,0,-0.1,0.252,-0.252,0.826,0,0,-1.4,1.5
ENSMUSG00000067878,MTAP7D3,MAP7 domain containing 3,nucleus|cytoplasm|centrosome|cytoskeleton|microtubule|membrane|,microtubule cytoskeleton organization|biological_process|,molecular_function|,10,0.1,0.0954,10,0.2,0.237,0.1,0.251,0.251,0.826,0,0,-1.1,1.7
ENSMUSG00000000861,BCL11A,B cell CLL/lymphoma 11A (zinc finger protein),nucleus|nucleus|cytoplasm|nuclear body|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of gene expression|positive regulation of neuron projection development|negative regulation of neuron projection development|protein sumoylation|B cell differentiation|T cell differentiation|negative regulation of collateral sprouting|positive regulation of collateral sprouting|regulation of dendrite development|negative regulation of dendrite development|regulation of RNA biosynthetic process|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|transcription corepressor activity|protein binding|metal ion binding|protein heterodimerization activity|,10,-0.3,0.562,10,0.5,1.71,0.1,0.247,0.247,0.827,0,0,-1.4,1.6
ENSMUSG00000054196,CTHRC1,collagen triple helix repeat containing 1,extracellular region|proteinaceous extracellular matrix|collagen trimer|extracellular space|cytoplasm|extracellular matrix|,"cell migration|positive regulation of protein binding|positive regulation of osteoblast proliferation|ossification involved in bone remodeling|positive regulation of osteoblast differentiation|Wnt signaling pathway, planar cell polarity pathway|inner ear receptor stereocilium organization|negative regulation of canonical Wnt signaling pathway|cochlea morphogenesis|establishment of planar polarity involved in neural tube closure|",frizzled binding|protein binding|Wnt-protein binding|,10,0.3,1.01,10,0,0,0.2,0.244,0.244,0.828,0,0,-1.7,1.4
ENSMUSG00000025010,CCNJ,cyclin J,cellular_component|nucleus|,biological_process|,molecular_function|,10,-0.3,0.512,10,-0.1,0.0469,-0.2,0.242,-0.242,0.829,0,0,-1.8,1.1
ENSMUSG00000054958,NT5C1A,"5'-nucleotidase, cytosolic IA",cellular_component|cytoplasm|,nucleotide metabolic process|purine nucleoside monophosphate catabolic process|dephosphorylation|adenosine metabolic process|,nucleotide binding|magnesium ion binding|5'-nucleotidase activity|hydrolase activity|,10,-0.2,0.11,10,-0.1,0.191,-0.1,0.237,-0.237,0.83,0,0,-1.6,1.3
ENSMUSG00000015619,GATA3,GATA binding protein 3,nuclear chromatin|intracellular|cell|nucleus|nucleus|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|in utero embryonic development|cell fate determination|neuron migration|cell activation|positive regulation of cytokine production|kidney development|mesonephros development|lens development in camera-type eye|immune system process|pro-T cell differentiation|aortic valve morphogenesis|cardiac right ventricle morphogenesis|ventricular septum development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|humoral immune response|signal transduction|nervous system development|axon guidance|negative regulation of cell proliferation|male gonad development|post-embryonic development|positive regulation of signal transduction|positive regulation of endothelial cell migration|negative regulation of gene expression|regulation of neuron projection development|phosphatidylinositol 3-kinase signaling|neuron differentiation|T cell differentiation|T cell differentiation|erythrocyte differentiation|TOR signaling|negative regulation of interferon-gamma production|negative regulation of interferon-gamma production|negative regulation of interleukin-2 production|positive regulation of interleukin-13 production|positive regulation of interleukin-4 production|positive regulation of interleukin-4 production|positive regulation of interleukin-5 production|T cell differentiation in thymus|T cell differentiation in thymus|negative regulation of mammary gland epithelial cell proliferation|embryonic hemopoiesis|embryonic hemopoiesis|ureter maturation|parathyroid hormone secretion|regulation of cytokine biosynthetic process|norepinephrine biosynthetic process|inner ear morphogenesis|regulation of CD4-positive, alpha-beta T cell differentiation|regulation of neuron apoptotic process|ear development|thymic T cell selection|T-helper 2 cell differentiation|innate immune response|positive regulation of T cell differentiation|positive regulation of cell differentiation|negative regulation of fat cell differentiation|negative regulation of cell cycle|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|sympathetic nervous system development|thymus development|embryonic organ development|developmental growth|anatomical structure formation involved in morphogenesis|homeostasis of number of cells|negative regulation of inflammatory response|T cell receptor signaling pathway|regulation of histone H3-K4 methylation|positive regulation of protein kinase B signaling|parathyroid gland development|pharyngeal system development|uterus development|mesenchymal to epithelial transition|mast cell differentiation|ureteric bud formation|regulation of histone H3-K27 methylation|canonical Wnt signaling pathway involved in metanephric kidney development|cellular response to cytokine stimulus|cellular response to interleukin-4|otic vesicle development|cellular response to BMP stimulus|renal system development|positive regulation of ureteric bud formation|nephric duct morphogenesis|nephric duct formation|regulation of nephron tubule epithelial cell differentiation|interleukin-4 secretion|interferon-gamma secretion|lymphocyte migration|regulation of establishment of cell polarity|negative regulation of cell motility|negative regulation of endothelial cell apoptotic process|negative regulation of cell proliferation involved in mesonephros development|positive regulation of thyroid hormone generation|positive regulation of interleukin-5 secretion|positive regulation of interleukin-13 secretion|positive regulation of transcription regulatory region DNA binding|positive regulation of transcription regulatory region DNA binding|regulation of cellular response to X-ray|negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation|negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|core promoter sequence-specific DNA binding|nucleic acid binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|enhancer sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription coactivator activity|interleukin-2 receptor binding|protein binding|transcription factor binding|zinc ion binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|protein dimerization activity|E-box binding|HMG box domain binding|,10,0,0,9,-0.2,0.661,-0.1,0.235,-0.235,0.831,0,0,-1.6,1.4
ENSMUSG00000028635,EDN2,endothelin 2,extracellular region|extracellular space|intracellular|,prostaglandin biosynthetic process|prostaglandin biosynthetic process|ovarian follicle rupture|temperature homeostasis|positive regulation of leukocyte chemotaxis|regulation of systemic arterial blood pressure by endothelin|positive regulation of cytosolic calcium ion concentration|protein kinase C-activating G-protein coupled receptor signaling pathway|regulation of blood pressure|positive regulation of cell proliferation|positive regulation of heart rate|artery smooth muscle contraction|vein smooth muscle contraction|cytokine-mediated signaling pathway|regulation of vasoconstriction|calcium-mediated signaling|neutrophil chemotaxis|macrophage activation|vasoconstriction|positive regulation of smooth muscle contraction|positive regulation of smooth muscle contraction|positive regulation of hormone secretion|negative regulation of hormone secretion|inositol phosphate-mediated signaling|macrophage chemotaxis|lung alveolus development|regulation of blood vessel size|positive regulation of prostaglandin-endoperoxide synthase activity|positive regulation of prostaglandin-endoperoxide synthase activity|energy homeostasis|,hormone activity|,10,-0.2,0.187,10,-0.1,0.109,-0.1,0.234,-0.234,0.831,0,0,-1.4,1.5
ENSMUSG00000021298,GPR132,G protein-coupled receptor 132,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,G1/S transition of mitotic cell cycle|signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0.2,0.546,0.1,0.233,0.233,0.831,0,0,-1.3,1.6
ENSMUSG00000044674,FZD1,frizzled homolog 1 (Drosophila),cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|neuron projection membrane|neuron projection|apical part of cell|,"positive regulation of protein phosphorylation|vasculature development|membranous septum morphogenesis|muscular septum morphogenesis|outflow tract morphogenesis|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|Wnt signaling pathway, calcium modulating pathway|cell-cell signaling|cell-cell signaling|multicellular organismal development|axonogenesis|brain development|gonad development|Wnt signaling pathway|Wnt signaling pathway|negative regulation of BMP signaling pathway|epithelial cell differentiation|epithelial cell differentiation|negative regulation of catenin import into nucleus|autocrine signaling|response to drug|canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt signaling pathway involved in osteoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|lung alveolus development|positive regulation of sequence-specific DNA binding transcription factor activity|hard palate development|canonical Wnt signaling pathway|canonical Wnt signaling pathway|ventricular septum morphogenesis|negative regulation of canonical Wnt signaling pathway|planar cell polarity pathway involved in neural tube closure|",signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|receptor binding|frizzled binding|Wnt-protein binding|Wnt-protein binding|PDZ domain binding|PDZ domain binding|identical protein binding|protein homodimerization activity|Wnt-activated receptor activity|Wnt-activated receptor activity|protein heterodimerization activity|,10,0.1,0.338,10,-0.2,0.507,0.1,0.228,0.228,0.833,0,0,-1.3,1.6
ENSMUSG00000027525,PHACTR3,phosphatase and actin regulator 3,nucleus|,biological_process|,actin binding|protein phosphatase inhibitor activity|,10,0.1,0.291,10,0,0,0.1,0.222,0.222,0.835,0,0,-1,1.8
ENSMUSG00000058444,MAP2K5,mitogen-activated protein kinase kinase 5,intracellular|nucleus|cytoplasm|spindle|cytosol|,negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|activation of MAPK activity|protein phosphorylation|heart development|phosphorylation|positive regulation of cell growth|negative regulation of NF-kappaB transcription factor activity|negative regulation of heterotypic cell-cell adhesion|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of interleukin-8 biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of epithelial cell proliferation|positive regulation of protein metabolic process|negative regulation of response to cytokine stimulus|ERK5 cascade|cellular response to growth factor stimulus|negative regulation of cell migration involved in sprouting angiogenesis|negative regulation of chemokine (C-X-C motif) ligand 2 production|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.3,1.15,10,0,0,0.2,0.212,0.212,0.838,0,0,-1.1,1.7
ENSMUSG00000028031,DKK2,dickkopf homolog 2 (Xenopus laevis),extracellular region|extracellular space|,multicellular organismal development|Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,None,9,0.2,0.119,9,-0.4,1.48,-0.1,0.212,-0.212,0.838,0,0,-1.8,1.1
ENSMUSG00000007877,TCAP,titin-cap,cytoplasm|Z disc|Z disc|I band|,cardiac muscle hypertrophy|adult heart development|cardiac muscle hypertrophy in response to stress|skeletal muscle thin filament assembly|skeletal muscle myosin thick filament assembly|detection of muscle stretch|sarcomere organization|sarcomere organization|cardiac muscle fiber development|sarcomerogenesis|cardiac myofibril assembly|cardiac muscle tissue morphogenesis|cardiac muscle contraction|,"protein binding|structural constituent of muscle|protein binding, bridging|titin binding|ion channel binding|FATZ binding|titin Z domain binding|",10,0.8,2.14,10,0.1,0.0136,0.1,0.21,0.21,0.838,0,0,-0.5,2
ENSMUSG00000039168,DAP,death-associated protein,cellular_component|,"autophagy|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of autophagy|negative regulation of NF-kappaB transcription factor activity|cellular response to amino acid starvation|negative regulation of transcription, DNA-templated|apoptotic signaling pathway|",death domain binding|,10,0.1,0.139,10,0.2,0.104,0.1,0.209,0.209,0.839,0,0,-1.2,1.6
ENSMUSG00000000903,VPREB3,pre-B lymphocyte gene 3,endoplasmic reticulum|,negative regulation of immunoglobulin secretion|,molecular_function|,10,0,0,10,-0.1,0.278,-0.1,0.203,-0.203,0.84,0,0,-1.7,1.2
ENSMUSG00000019929,DCN,decorin,extracellular region|proteinaceous extracellular matrix|collagen type VI trimer|extracellular space|extracellular matrix|extracellular matrix|,peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|,collagen binding|glycosaminoglycan binding|poly(A) RNA binding|protein N-terminus binding|extracellular matrix binding|,10,0.2,0.11,10,0.1,0.2,0.2,0.201,0.201,0.841,0,0,-1.8,1.2
ENSMUSG00000091387,GCNT4,"glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)",Golgi apparatus|membrane|integral component of membrane|,inter-male aggressive behavior|thyroid hormone metabolic process|tissue morphogenesis|tissue morphogenesis|homeostasis of number of cells|kidney morphogenesis|,"beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.517,10,0,0,0.1,0.199,0.199,0.842,0,0,-1.7,1.3
ENSMUSG00000024056,NDC80,"NDC80 homolog, kinetochore complex component (S. cerevisiae)","chromosome, centromeric region|kinetochore|condensed chromosome kinetochore|condensed nuclear chromosome outer kinetochore|nucleus|chromosome|membrane|Ndc80 complex|",mitotic sister chromatid segregation|establishment of mitotic spindle orientation|cell cycle|mitotic spindle organization|chromosome segregation|mitotic nuclear division|attachment of spindle microtubules to kinetochore|cell division|,protein binding|,9,-0.2,0.328,9,0.3,0.655,0.1,0.198,0.198,0.842,0,0,-1.3,1.7
ENSMUSG00000033083,TBC1D4,"TBC1 domain family, member 4",cytoplasm|membrane-bounded vesicle|extracellular vesicular exosome|,vesicle-mediated transport|negative regulation of vesicle fusion|regulation of Rab GTPase activity|cellular response to insulin stimulus|,GTPase activator activity|Rab GTPase activator activity|protein binding|,10,0.8,2.27,10,-0.1,0.134,0.3,0.197,0.197,0.842,0,0,-0.7,2
ENSMUSG00000025776,CRISPLD1,cysteine-rich secretory protein LCCL domain containing 1,extracellular region|extracellular vesicular exosome|,face morphogenesis|,molecular_function|,10,0,0,10,-1.1,1.69,-0.1,0.196,-0.196,0.843,0,0,-2,0.5
ENSMUSG00000031380,FIGF,c-fos induced growth factor,extracellular region|extracellular space|membrane|,angiogenesis|multicellular organismal development|cell proliferation|positive regulation of cell proliferation|cell differentiation|regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of interleukin-6 production|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|positive chemotaxis|induction of positive chemotaxis|positive regulation of cell division|positive regulation of mast cell chemotaxis|,vascular endothelial growth factor receptor binding|protein binding|growth factor activity|chemoattractant activity|protein homodimerization activity|vascular endothelial growth factor receptor 3 binding|,10,0,0,10,-0.2,0.599,-0.1,0.194,-0.194,0.843,0,0,-1.6,1.3
ENSMUSG00000067242,LGI1,"leucine-rich repeat LGI family, member 1",extracellular region|extracellular space|extracellular space|cell junction|synapse|,axon guidance|positive regulation of cell growth|neuron projection development|positive regulation of synaptic transmission|protein homooligomerization|,protein binding|,10,-0.7,0.962,10,0,0,-0.1,0.193,-0.193,0.844,0,0,-1.8,1.3
ENSMUSG00000040998,NPNT,nephronectin,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|basement membrane|membrane|smooth muscle contractile fiber|extracellular matrix|integrin alpha8-beta1 complex|extracellular vesicular exosome|,ureteric bud development|branching involved in ureteric bud morphogenesis|cell adhesion|cell-matrix adhesion|cell-matrix adhesion|multicellular organismal development|positive regulation of alkaline phosphatase activity|positive regulation of cell-substrate adhesion|cell differentiation|extracellular matrix organization|positive regulation of transforming growth factor beta receptor signaling pathway|cell-cell adhesion mediated by integrin|establishment of protein localization|positive regulation of osteoblast differentiation|positive regulation of smooth muscle contraction|positive regulation of ERK1 and ERK2 cascade|cellular response to tumor necrosis factor|pilomotor reflex|positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|,integrin binding|integrin binding|calcium ion binding|,10,0.1,0.0996,10,-0.2,0.644,-0.1,0.191,-0.191,0.844,0,0,-1.2,1.8
ENSMUSG00000027332,IVD,isovaleryl coenzyme A dehydrogenase,mitochondrion|mitochondrial matrix|mitochondrial membrane|,leucine catabolic process|metabolic process|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|isovaleryl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|flavin adenine dinucleotide binding|",10,0.3,0.322,10,0,0,0.2,0.19,0.19,0.844,0,0,-1.1,1.7
ENSMUSG00000071470,CCNB1IP1,cyclin B1 interacting protein 1,synaptonemal complex|nucleus|chromosome|,blastocyst formation|meiotic nuclear division|reciprocal meiotic recombination|spermatid development|protein ubiquitination|chiasma assembly|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-1,2.86,10,0.1,0.076,-0.2,0.188,-0.188,0.845,0,0,-2,0.7
ENSMUSG00000040594,RANBP17,RAN binding protein 17,intracellular|cell|nucleus|nuclear pore|cytoplasm|,transport|intracellular protein transport|nucleocytoplasmic transport|protein transport|mRNA transport|,Ran GTPase binding|,10,-0.3,1.69,10,0,0,-0.1,0.188,-0.188,0.845,0,0,-1.7,1.1
ENSMUSG00000048332,LHFP,lipoma HMGIC fusion partner,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.68,10,0,0,0.1,0.184,0.184,0.847,0,0,-1.3,1.6
ENSMUSG00000019828,GRM1,"glutamate receptor, metabotropic 1",nucleus|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|postsynaptic density|postsynaptic density|membrane|integral component of membrane|axon|dendrite|G-protein coupled receptor dimeric complex|G-protein coupled receptor homodimeric complex|presynaptic membrane|neuron projection|neuronal cell body|dendritic spine|postsynaptic membrane|,"activation of MAPKK activity|activation of MAPK activity|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|locomotory behavior|sensory perception of pain|calcium-mediated signaling|dimeric G-protein coupled receptor signaling pathway|regulation of MAPK cascade|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|regulation of sensory perception of pain|regulation of synaptic transmission, glutamatergic|regulation of synaptic transmission, glutamatergic|cellular response to electrical stimulus|",PLC activating G-protein coupled glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|protein binding|glutamate receptor activity|glutamate receptor activity|estrogen receptor binding|identical protein binding|,10,-0.1,0.364,10,0,0,-0.1,0.183,-0.183,0.847,0,0,-1.4,1.5
ENSMUSG00000009350,MPO,myeloperoxidase,extracellular space|nucleus|mitochondrion|lysosome|secretory granule|azurophil granule|extracellular vesicular exosome|,response to yeast|hypochlorous acid biosynthetic process|respiratory burst involved in defense response|response to oxidative stress|removal of superoxide radicals|low-density lipoprotein particle remodeling|hydrogen peroxide catabolic process|hydrogen peroxide catabolic process|hydrogen peroxide catabolic process|negative regulation of growth of symbiont in host|defense response to fungus|oxidation-reduction process|oxidation-reduction process|,peroxidase activity|peroxidase activity|peroxidase activity|heparin binding|oxidoreductase activity|heme binding|metal ion binding|,9,0.9,2.84,9,-0.1,0.148,0.8,0.18,0.18,0.848,0,0,-0.6,2
ENSMUSG00000064057,SCGB3A1,"secretoglobin, family 3A, member 1",extracellular region|extracellular space|extracellular vesicular exosome|,biological_process|,molecular_function|cytokine activity|,10,-0.2,0.549,10,0.4,0.313,-0.1,0.179,-0.179,0.848,0,0,-1.4,1.6
ENSMUSG00000075415,FNBP1,formin binding protein 1,cellular_component|cytoplasm|lysosome|cytoskeleton|plasma membrane|coated pit|membrane|cytoplasmic vesicle|,endocytosis|nervous system development|,protein binding|lipid binding|identical protein binding|,10,-0.3,0.625,10,0,0,-0.1,0.177,-0.177,0.849,0,0,-1.1,1.9
ENSMUSG00000033253,SZT2,seizure threshold 2,peroxisome|extracellular vesicular exosome|,central nervous system development|embryo development|post-embryonic development|corpus callosum morphogenesis|pigmentation|regulation of superoxide dismutase activity|,molecular_function|,10,0,0,10,-0.2,0.232,-0.1,0.176,-0.176,0.849,0,0,-1.6,1.4
ENSMUSG00000053916,NANP,N-acetylneuraminic acid phosphatase,cellular_component|,dephosphorylation|N-acetylneuraminate biosynthetic process|,N-acylneuraminate-9-phosphatase activity|,10,-0.1,0.0717,10,1.3,2.28,-0.1,0.169,-0.169,0.851,0,0,-1,2
ENSMUSG00000020963,TSHR,thyroid stimulating hormone receptor,plasma membrane|membrane|integral component of membrane|receptor complex|membrane raft|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|positive regulation of cell proliferation|adult locomotory behavior|B cell differentiation|thyroid-stimulating hormone signaling pathway|thyroid-stimulating hormone signaling pathway|regulation of locomotion|positive regulation of multicellular organism growth|,signal transducer activity|G-protein coupled receptor activity|thyroid-stimulating hormone receptor activity|thyroid-stimulating hormone receptor activity|protein-hormone receptor activity|,10,-0.2,0.366,10,0.3,0.389,0.2,0.167,0.167,0.852,0,0,-0.8,2
ENSMUSG00000091337,EID1,EP300 interacting inhibitor of differentiation 1,nucleus|cytoplasm|aggresome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|cell differentiation|regulation of histone acetylation|negative regulation of transcription, DNA-templated|regulation of catalytic activity|regulation of RNA biosynthetic process|",transcription corepressor activity|protein binding|histone acetyltransferase regulator activity|histone acetyltransferase binding|,9,1.1,2.38,9,0,0,0.1,0.165,0.165,0.853,0,0,-0.5,2
ENSMUSG00000019857,ASF1A,anti-silencing function 1A histone chaperone,nuclear chromatin|nucleus|protein complex|,"osteoblast differentiation|DNA repair|chromatin assembly or disassembly|nucleosome assembly|DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|muscle cell differentiation|",chromatin binding|histone binding|,10,-0.7,0.648,10,0.1,0.255,0.1,0.162,0.162,0.854,0,0,-1.7,1.5
ENSMUSG00000056124,B4GALT6,"UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6",cellular_component|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|sphingolipid biosynthetic process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.1,0.147,10,-0.2,0.036,0.1,0.147,0.147,0.858,0,0,-1.6,1.3
ENSMUSG00000068079,TCF15,transcription factor 15,nucleus|,"somitogenesis|respiratory system process|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|muscle organ development|anterior/posterior pattern specification|death|post-anal tail morphogenesis|eating behavior|ear development|skin development|establishment of epithelial cell apical/basal polarity|paraxial mesoderm development|muscle organ morphogenesis|skeletal system morphogenesis|neuromuscular process controlling posture|mesenchymal to epithelial transition|regulation of gene expression involved in extracellular matrix organization|",DNA binding|protein dimerization activity|,10,0.1,0.258,10,0,0,0.1,0.145,0.145,0.858,0,0,-1.1,1.8
ENSMUSG00000069835,SAT2,spermidine/spermine N1-acetyl transferase 2,cytoplasm|extracellular vesicular exosome|,spermine metabolic process|spermidine metabolic process|spermidine acetylation|spermine acetylation|putrescine acetylation|nor-spermidine metabolic process|,"diamine N-acetyltransferase activity|diamine N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.1,0.225,10,0,0,0.1,0.143,0.143,0.859,0,0,-0.9,1.9
ENSMUSG00000047030,SPATA2,spermatogenesis associated 2,nucleus|nucleolus|cytoplasm|,biological_process|,molecular_function|,10,-0.1,0.256,10,0,0,-0.1,0.142,-0.142,0.859,0,0,-1.3,1.6
ENSMUSG00000049971,GLT1D1,glycosyltransferase 1 domain containing 1,extracellular region|cytoplasm|,biological_process|biosynthetic process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.1,0.185,10,1.4,2.36,-0.1,0.14,-0.14,0.86,0,0,-0.9,2
ENSMUSG00000022802,LMLN,leishmanolysin-like (metallopeptidase M8 family),cytoplasm|lipid particle|focal adhesion|membrane|,proteolysis|cell cycle|mitotic nuclear division|cell adhesion|biological_process|cell division|,molecular_function|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,-0.4,0.62,10,0.3,0.797,0.1,0.139,0.139,0.86,0,0,-1.5,1.3
ENSMUSG00000003813,RAD23A,RAD23a homolog (S. cerevisiae),proteasome complex|nucleus|cytoplasm|,DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|regulation of proteasomal ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of viral genome replication|,damaged DNA binding|polyubiquitin binding|ubiquitin-specific protease binding|,10,-0.2,0.73,10,0,0,-0.1,0.138,-0.138,0.861,0,0,-2,0.8
ENSMUSG00000029561,OASL2,2'-5' oligoadenylate synthetase-like 2,cellular_component|,immune system process|purine nucleotide biosynthetic process|immune response|response to virus|innate immune response|defense response to virus|,nucleotide binding|2'-5'-oligoadenylate synthetase activity|RNA binding|double-stranded RNA binding|ATP binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,0,0,10,-0.3,0.379,-0.1,0.137,-0.137,0.861,0,0,-1.8,1.1
ENSMUSG00000055373,FUT9,fucosyltransferase 9,Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|nervous system development|fucosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,0.8,1.52,-0.1,0.137,-0.137,0.861,0,0,-0.9,2
ENSMUSG00000026567,ADCY10,adenylate cyclase 10,cytoplasm|cytoplasm|cytosol|cytoskeleton|plasma membrane|membrane|axon|dendrite|growth cone|neuronal cell body|apical part of cell|basal part of cell|,cAMP biosynthetic process|cAMP biosynthetic process|spermatogenesis|cyclic nucleotide biosynthetic process|intracellular signal transduction|positive regulation of apoptotic process|,nucleotide binding|magnesium ion binding|adenylate cyclase activity|adenylate cyclase activity|ATP binding|lyase activity|phosphorus-oxygen lyase activity|manganese ion binding|metal ion binding|ATPase binding|,10,-0.1,0.119,10,0.1,0.27,0.1,0.134,0.134,0.862,0,0,-0.9,1.9
ENSMUSG00000049892,RASD1,"RAS, dexamethasone-induced 1",nucleus|cytoplasm|plasma membrane|membrane|perinuclear region of cytoplasm|,"GTP catabolic process|signal transduction|nitric oxide mediated signal transduction|small GTPase mediated signal transduction|negative regulation of transcription, DNA-templated|",nucleotide binding|protein binding|GTP binding|,10,0,0,10,-0.1,0.322,-0.1,0.133,-0.133,0.862,0,0,-1.7,1.2
ENSMUSG00000079415,CNTF,ciliary neurotrophic factor,extracellular space|nucleus|cytoplasm|cytosol|axon|cell projection cytoplasm|neuronal cell body|CRLF-CLCF1 complex|,JAK-STAT cascade|multicellular organismal development|nervous system development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of phosphatidylinositol 3-kinase signaling|cell differentiation|positive regulation of cell growth|growth|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of MAPK cascade|negative regulation of neuron apoptotic process|positive regulation of JAK-STAT cascade|negative regulation of photoreceptor cell differentiation|regulation of retinal cell programmed cell death|positive regulation of hormone secretion|astrocyte activation|muscle organ morphogenesis|neuron development|positive regulation of axon regeneration|protein heterooligomerization|regulation of resting membrane potential|membrane hyperpolarization|ciliary neurotrophic factor-mediated signaling pathway|negative regulation of neuron death|,cytokine activity|ciliary neurotrophic factor receptor binding|interleukin-6 receptor binding|growth factor activity|,10,0,0,10,-0.1,0.166,-0.1,0.128,-0.128,0.864,0,0,-1.7,1.2
ENSMUSG00000035458,TNNI3,"troponin I, cardiac 3",cytoplasm|troponin complex|myofibril|sarcomere|sarcomere|contractile fiber|,vasculogenesis|regulation of systemic arterial blood pressure by ischemic conditions|cellular calcium ion homeostasis|cellular calcium ion homeostasis|regulation of muscle contraction|regulation of smooth muscle contraction|striated muscle contraction|heart development|negative regulation of ATPase activity|ventricular cardiac muscle tissue morphogenesis|heart contraction|cardiac muscle contraction|,actin binding|calcium channel inhibitor activity|protein kinase binding|protein domain specific binding|troponin C binding|troponin T binding|metal ion binding|calcium-dependent protein binding|,10,0,0,10,0.1,0.231,0.1,0.127,0.127,0.864,0,0,-1.2,1.7
ENSMUSG00000021256,VASH1,vasohibin 1,extracellular region|extracellular space|cytoplasm|endoplasmic reticulum|apical part of cell|,angiogenesis|negative regulation of endothelial cell proliferation|cell cycle|cell cycle arrest|response to wounding|negative regulation of endothelial cell migration|positive regulation of gene expression|negative regulation of angiogenesis|negative regulation of angiogenesis|negative regulation of angiogenesis|negative regulation of blood vessel endothelial cell migration|regulation of angiogenesis|negative regulation of lymphangiogenesis|regulation of cellular senescence|,molecular_function|,10,0,0,10,0.6,0.44,0.1,0.127,0.127,0.864,0,0,-0.9,1.9
ENSMUSG00000023944,HSP90AB1,"heat shock protein 90 alpha (cytosolic), class B member 1",intracellular|cytoplasm|cytoplasm|mitochondrion|mitochondrion|cytosol|COP9 signalosome|cell surface|membrane|inclusion body|basolateral plasma membrane|apical plasma membrane|brush border membrane|extracellular vesicular exosome|,"placenta development|protein folding|response to stress|positive regulation of protein binding|positive regulation of protein import into nucleus, translocation|negative regulation of neuron apoptotic process|positive regulation of cell size|cellular response to interleukin-4|positive regulation of protein serine/threonine kinase activity|",nucleotide binding|UTP binding|CTP binding|double-stranded RNA binding|protein binding|ATP binding|GTP binding|sulfonylurea receptor binding|protein kinase binding|MHC class II protein complex binding|dATP binding|ion channel binding|poly(A) RNA binding|unfolded protein binding|,3,0.1,0.289,5,0,0,0.1,0.119,0.119,0.866,0,0,-1.4,2
ENSMUSG00000033068,ENTPD6,ectonucleoside triphosphate diphosphohydrolase 6,extracellular space|Golgi apparatus|plasma membrane|cell surface|extracellular vesicular exosome|,metabolic process|response to magnesium ion|response to calcium ion|,"guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity|hydrolase activity|nucleoside-diphosphatase activity|nucleoside-triphosphatase activity|",10,-0.8,1.25,10,-0.1,0.0102,-0.4,0.115,-0.115,0.868,0,0,-1.9,0.8
ENSMUSG00000033060,LMO7,LIM domain only 7,cell-cell adherens junction|apical plasma membrane|,single organismal cell-cell adhesion|,protein C-terminus binding|actinin binding|metal ion binding|,10,0.2,0.997,10,2,1.73,0.1,0.113,0.113,0.868,0,0,-1,4
ENSMUSG00000032463,FAIM,Fas apoptotic inhibitory molecule,cytoplasm|,apoptotic process|negative regulation of apoptotic process|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|,None,10,-0.4,1.21,10,0,0,-0.2,0.111,-0.111,0.869,0,0,-1.7,1.2
ENSMUSG00000041324,INHBA,inhibin beta-A,extracellular region|cell|activin A complex|inhibin A complex|,"G1/S transition of mitotic cell cycle|ovarian follicle development|mesoderm formation|hair follicle development|hematopoietic progenitor cell differentiation|hematopoietic progenitor cell differentiation|regulation of transcription from RNA polymerase II promoter|cell cycle arrest|negative regulation of cell proliferation|male gonad development|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of cell growth|positive regulation of cellular protein metabolic process|activin receptor signaling pathway|endodermal cell differentiation|growth|odontogenesis|response to drug|hemoglobin biosynthetic process|progesterone secretion|positive regulation of erythrocyte differentiation|negative regulation of cell cycle|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of follicle-stimulating hormone secretion|mesodermal cell differentiation|negative regulation of hair follicle development|palate development|positive regulation of ovulation|eyelid development in camera-type eye|cellular response to follicle-stimulating hormone stimulus|cellular response to cholesterol|extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|",receptor binding|cytokine activity|hormone activity|growth factor activity|peptide hormone binding|identical protein binding|protein heterodimerization activity|type II activin receptor binding|,10,0.2,0.0977,10,0.1,0.0541,0.1,0.108,0.108,0.87,0,0,-0.9,2
ENSMUSG00000039982,DTX4,deltex 4 homolog (Drosophila),cellular_component|cytoplasm|,Notch signaling pathway|biological_process|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,1,2.1,0.1,0.108,0.108,0.87,0,0,-1.1,2
ENSMUSG00000032056,BTG4,B cell translocation gene 4,cellular_component|,negative regulation of mitotic cell cycle|,molecular_function|,9,-1.4,1.88,9,0,0,-0.1,0.104,-0.104,0.871,0,0,-3,1.1
ENSMUSG00000078144,CAPNS2,"calpain, small subunit 2",cytoplasm|plasma membrane|membrane|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|metal ion binding|,9,0.1,0.0103,9,1.4,2.38,-0.1,0.101,-0.101,0.872,0,0,-0.6,3
ENSMUSG00000037583,NR0B2,"nuclear receptor subfamily 0, group B, member 2",nucleus|cytoplasm|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|response to glucose|positive regulation of insulin secretion|steroid hormone mediated signaling pathway|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|transcription corepressor activity|protein binding|transcription factor binding|protein domain specific binding|protein complex binding|protein homodimerization activity|retinoic acid receptor binding|peroxisome proliferator activated receptor binding|retinoid X receptor binding|thyroid hormone receptor binding|,10,-0.4,0.744,10,0.3,0.961,0.1,0.0998,0.0998,0.872,0,0,-1.6,1.4
ENSMUSG00000022997,WNT1,"wingless-type MMTV integration site family, member 1",extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|cell surface|,"embryonic axis specification|branching involved in ureteric bud morphogenesis|positive regulation of protein phosphorylation|signal transduction|cell-cell signaling|cell-cell signaling|multicellular organismal development|myoblast fusion|myoblast fusion|positive regulation of cell proliferation|positive regulation of cell proliferation|organ morphogenesis|positive regulation of lamellipodium assembly|negative regulation of cell-substrate adhesion|myotube differentiation|Wnt signaling pathway|Wnt signaling pathway|spinal cord association neuron differentiation|diencephalon development|central nervous system morphogenesis|cerebellum formation|forebrain anterior/posterior pattern specification|midbrain-hindbrain boundary maturation during brain development|metencephalon development|negative regulation of cell-cell adhesion|BMP signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|ubiquitin-dependent SMAD protein catabolic process|midbrain development|midbrain-hindbrain boundary development|organ regeneration|T cell differentiation in thymus|inner ear morphogenesis|signal transduction in response to DNA damage|positive regulation of insulin-like growth factor receptor signaling pathway|canonical Wnt signaling pathway involved in negative regulation of apoptotic process|negative regulation of cell differentiation|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|positive regulation of Notch signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fibroblast proliferation|neuron fate commitment|neuron fate determination|positive regulation of sequence-specific DNA binding transcription factor activity|Spemann organizer formation|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|bone development|positive regulation of dermatome development|hepatocyte differentiation|hematopoietic stem cell proliferation|negative regulation of cell aging|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|",receptor binding|frizzled binding|cytokine activity|protein binding|protein domain specific binding|transcription regulatory region DNA binding|,10,0.5,1.9,10,0,0,0.1,0.0997,0.0997,0.872,0,0,-0.7,2
ENSMUSG00000034462,PKD2,polycystic kidney disease 2,polycystin complex|cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|plasma membrane|integral component of plasma membrane|cell-cell junction|cilium|cilium|basal plasma membrane|membrane|integral component of membrane|lamellipodium|motile primary cilium|nonmotile primary cilium|filamentous actin|ciliary basal body|ciliary basal body|cell projection|basal cortex|basal cortex|extracellular vesicular exosome|integral component of cytoplasmic side of endoplasmic reticulum membrane|integral component of lumenal side of endoplasmic reticulum membrane|mitotic spindle|mitotic spindle|,"kidney development|kidney development|liver development|embryonic placenta development|heart looping|detection of nodal flow|transport|ion transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|cell cycle arrest|positive regulation of cytosolic calcium ion concentration|JAK-STAT cascade|determination of left/right symmetry|heart development|positive regulation of gene expression|regulation of cAMP metabolic process|positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|sodium ion transmembrane transport|regulation of cell proliferation|cytoplasmic sequestering of transcription factor|positive regulation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|detection of mechanical stimulus|release of sequestered calcium ion into cytosol|release of sequestered calcium ion into cytosol|transmembrane transport|negative regulation of ryanodine-sensitive calcium-release channel activity|placenta blood vessel development|renal tubule morphogenesis|calcium ion transmembrane transport|calcium ion transmembrane transport|positive regulation of cell cycle arrest|cellular response to hydrostatic pressure|cellular response to osmotic stress|cellular response to fluid shear stress|cellular response to fluid shear stress|potassium ion transmembrane transport|determination of liver left/right asymmetry|renal system development|regulation of calcium ion import|negative regulation of G1/S transition of mitotic cell cycle|",receptor binding|receptor binding|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated sodium channel activity|calcium channel activity|calcium channel activity|potassium channel activity|calcium ion binding|protein binding|cytoskeletal protein binding|channel activity|voltage-gated cation channel activity|identical protein binding|identical protein binding|protein homodimerization activity|actinin binding|HLH domain binding|ion channel binding|metal ion binding|calcium-induced calcium release activity|ATPase binding|phosphoprotein binding|muscle alpha-actinin binding|alpha-actinin binding|,10,-0.6,0.59,10,0.5,1.02,0.1,0.0996,0.0996,0.872,0,0,-1.6,1.5
ENSMUSG00000028583,PDPN,podoplanin,ruffle|plasma membrane|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|apical plasma membrane|lamellipodium|filopodium|cell projection|,cell morphogenesis|lymphangiogenesis|prostaglandin metabolic process|cellular component movement|cell adhesion|signal transduction|multicellular organismal development|cell proliferation|regulation of cell shape|positive regulation of platelet activation|single organismal cell-cell adhesion|lung development|positive regulation of cell migration|tube morphogenesis|lung alveolus development|positive regulation of cellular component movement|visceral serous pericardium development|regulation of G1/S transition of mitotic cell cycle|,None,10,-0.3,1.72,10,0,0,-0.1,0.0988,-0.0988,0.873,0,0,-1.7,1.1
ENSMUSG00000030589,RASGRP4,RAS guanyl releasing protein 4,intracellular|cytoplasm|plasma membrane|membrane|,small GTPase mediated signal transduction|cell proliferation|response to extracellular stimulus|cell growth|cell differentiation|positive regulation of Ras GTPase activity|intracellular signal transduction|positive regulation of Ras protein signal transduction|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|metal ion binding|,10,0.1,0.162,10,-0.1,0.061,0.1,0.0987,0.0987,0.873,0,0,-1,1.8
ENSMUSG00000042331,SPECC1,sperm antigen with calponin homology and coiled-coil domains 1,nucleus|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.25,-0.1,0.0919,-0.0919,0.875,0,0,-1.7,1.2
ENSMUSG00000034040,WBSCR17,Williams-Beuren syndrome chromosome region 17 homolog (human),cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",9,-0.1,0.115,10,-0.3,0.135,-0.1,0.0888,-0.0888,0.876,0,0,-1.9,0.9
ENSMUSG00000026167,WNT10A,"wingless-type MMTV integration site family, member 10A",extracellular region|proteinaceous extracellular matrix|extracellular space|,hair follicle development|signal transduction|cell-cell signaling|multicellular organismal development|organ morphogenesis|positive regulation of gene expression|neural crest cell differentiation|Wnt signaling pathway|neuron differentiation|hair follicle morphogenesis|odontogenesis|regulation of odontogenesis of dentin-containing tooth|tongue development|skin development|cell fate commitment|epidermis morphogenesis|sebaceous gland development|,receptor binding|frizzled binding|,10,0.9,0.671,10,-1.1,1.53,0.5,0.0886,0.0886,0.876,0,0,-1.8,1.7
ENSMUSG00000025527,SATL1,spermidine/spermine N1-acetyl transferase-like 1,cellular_component|,biological_process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,-0.1,0.176,10,0.2,0.446,0.1,0.0885,0.0885,0.876,0,0,-1.3,1.6
ENSMUSG00000025467,PRAP1,proline-rich acidic protein 1,extracellular region|,None,None,10,0,0,10,0.2,0.306,0.1,0.0849,0.0849,0.877,0,0,-1.2,1.7
ENSMUSG00000074802,GAS2L3,growth arrest-specific 2 like 3,cytoplasm|cytoskeleton|microtubule|actin cytoskeleton|microtubule cytoskeleton|,microtubule cytoskeleton organization|cell cycle arrest|actin cytoskeleton organization|,actin binding|microtubule binding|,9,0,0,9,-0.2,0.222,-0.1,0.0846,-0.0846,0.877,0,0,-1.6,1.4
ENSMUSG00000029433,DIABLO,diablo homolog (Drosophila),cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrial intermembrane space|mitochondrial intermembrane space|cytoplasmic side of plasma membrane|CD40 receptor complex|,apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|intrinsic apoptotic signaling pathway in response to oxidative stress|activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|positive regulation of apoptotic process|positive regulation of apoptotic process|neuron apoptotic process|intrinsic apoptotic signaling pathway|,None,10,-0.1,0.0823,10,-0.1,0.00941,-0.1,0.0835,-0.0835,0.877,0,0,-1.7,1.2
ENSMUSG00000024793,TNFRSF25,"tumor necrosis factor receptor superfamily, member 25",plasma membrane|,None,None,10,0.3,0.692,10,0,0,0.1,0.0807,0.0807,0.878,0,0,-1.6,1.4
ENSMUSG00000027394,TTL,tubulin tyrosine ligase,microtubule|,microtubule cytoskeleton organization|cellular protein modification process|regulation of axon extension|,nucleotide binding|tubulin-tyrosine ligase activity|tubulin-tyrosine ligase activity|ATP binding|ligase activity|,10,0.8,0.0287,10,0.1,0.122,0.1,0.0791,0.0791,0.879,0,0,-0.7,2
ENSMUSG00000027937,JTB,jumping translocation breakpoint,cytoplasm|mitochondrion|centrosome|spindle|cytoskeleton|membrane|integral component of membrane|midbody|,cytokinesis|apoptotic process|cell cycle|mitotic nuclear division|apoptotic mitochondrial changes|regulation of cell proliferation|positive regulation of protein kinase activity|cell division|,protein kinase binding|,10,0,0,10,0.2,0.477,0.1,0.079,0.079,0.879,0,0,-1.4,1.6
ENSMUSG00000015880,NCAPG,"non-SMC condensin I complex, subunit G",condensed chromosome|condensin complex|cytoplasm|cytoplasm|centrosome|actin cytoskeleton|membrane|,mitotic chromosome condensation|,molecular_function|,8,-1.1,1.85,8,-0.2,0.875,-1.1,0.077,-0.077,0.879,0,0,-2,0.7
ENSMUSG00000031529,TNKS,"tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase","chromosome, centromeric region|chromosome, telomeric region|nuclear chromosome, telomeric region|nucleus|nuclear pore|chromosome|cytoplasm|Golgi apparatus|cytosol|cytoskeleton|membrane|nuclear membrane|","protein polyubiquitination|protein ADP-ribosylation|transport|cell cycle|mitotic nuclear division|protein transport|Wnt signaling pathway|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|positive regulation of telomere maintenance via telomerase|negative regulation of DNA binding|positive regulation of transcription from RNA polymerase II promoter|mRNA transport|spindle assembly|cell division|protein localization to chromosome, telomeric region|protein poly-ADP-ribosylation|protein auto-ADP-ribosylation|positive regulation of canonical Wnt signaling pathway|","NAD+ ADP-ribosyltransferase activity|zinc ion binding|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0,0,10,0.1,0.28,0.1,0.0758,0.0758,0.88,0,0,-1.5,1.5
ENSMUSG00000030353,TEAD4,TEA domain family member 4,intracellular|nucleus|transcription factor complex|,"in utero embryonic development|cell fate specification|blastocyst formation|trophectodermal cell fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|embryo implantation|hippo signaling|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,0,0,10,0.5,1.42,0.1,0.0756,0.0756,0.88,0,0,-1.2,1.7
ENSMUSG00000050556,KCNB1,"potassium voltage gated channel, Shab-related subfamily, member 1",voltage-gated potassium channel complex|membrane|integral component of membrane|dendrite|dendrite membrane|neuronal cell body membrane|neuronal cell body|postsynaptic membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein oligomerization|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|protein binding|outward rectifier potassium channel activity|protein N-terminus binding|,10,-0.2,0.935,10,0,0,-0.1,0.0753,-0.0753,0.88,0,0,-1.7,1.2
ENSMUSG00000060534,DCC,deleted in colorectal carcinoma,membrane|integral component of membrane|axon|axon|growth cone membrane|membrane raft|,neuron migration|apoptotic process|multicellular organismal development|axon guidance|positive regulation of neuron projection development|spinal cord ventral commissure morphogenesis|dorsal/ventral axon guidance|anterior/posterior axon guidance|netrin-activated signaling pathway|positive regulation of ERK1 and ERK2 cascade|regulation of RNA biosynthetic process|,transcription coactivator activity|netrin receptor activity|protein binding|identical protein binding|,10,0,0,10,-0.2,0.585,-0.1,0.0737,-0.0737,0.88,0,0,-1.7,1.2
ENSMUSG00000023043,KRT18,keratin 18,nucleus|cytoplasm|microtubule organizing center|intermediate filament|intermediate filament|centriolar satellite|keratin filament|keratin filament|extracellular vesicular exosome|cell periphery|,tumor necrosis factor-mediated signaling pathway|Golgi to plasma membrane CFTR protein transport|negative regulation of apoptotic process|intermediate filament cytoskeleton organization|extrinsic apoptotic signaling pathway|hepatocyte apoptotic process|,structural molecule activity|protein binding|poly(A) RNA binding|scaffold protein binding|,10,0.1,0.373,10,-1,1.42,-0.1,0.0718,-0.0718,0.881,0,0,-2,0.8
ENSMUSG00000028047,THBS3,thrombospondin 3,extracellular region|perinuclear region of cytoplasm|,growth plate cartilage development|growth plate cartilage development|cell adhesion|ossification involved in bone maturation|bone trabecula formation|,calcium ion binding|heparin binding|,10,0.1,0.341,10,0,0,0.1,0.0704,0.0704,0.881,0,0,-1.4,1.6
ENSMUSG00000031137,FGF13,fibroblast growth factor 13,extracellular region|nucleus|nucleus|cytoplasm|cytoplasm|microtubule|plasma membrane|intercalated disc|filopodium|axon|dendrite|growth cone|cell projection|neuron projection|,MAPK cascade|neuron migration|negative regulation of microtubule depolymerization|nervous system development|learning|memory|hippocampus development|cerebral cortex cell migration|establishment of neuroblast polarity|positive regulation of protein kinase activity|microtubule polymerization|negative regulation of collateral sprouting|protein localization to plasma membrane|,receptor binding|microtubule binding|growth factor activity|sodium channel regulator activity|sodium channel regulator activity|protein kinase activator activity|ion channel binding|beta-tubulin binding|,9,0.5,1.49,9,0,0,0.3,0.0674,0.0674,0.882,0,0,-1.1,1.8
ENSMUSG00000049691,NKX3-2,NK3 homeobox 2,nucleus|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|determination of left/right symmetry|pancreas development|negative regulation of chondrocyte differentiation|middle ear morphogenesis|negative regulation of apoptotic process|organ development|spleen development|organ formation|skeletal system morphogenesis|embryonic skeletal system development|digestive system development|intestinal epithelial cell development|",DNA binding|sequence-specific DNA binding|,10,1.3,2.63,10,-0.2,0.362,-0.1,0.0645,-0.0645,0.883,0,0,-0.6,3
ENSMUSG00000030493,C230052I12RIK,RIKEN cDNA C230052I12 gene,nucleus|intracellular membrane-bounded organelle|Fanconi anaemia nuclear complex|,DNA repair|cellular response to DNA damage stimulus|biological_process|,DNA binding|chromatin binding|,10,0,0,10,-0.1,0.0776,-0.1,0.0578,-0.0578,0.885,0,0,-1.7,1.3
ENSMUSG00000054892,TXK,TXK tyrosine kinase,nucleus|cytoplasm|plasma membrane|membrane|,"cytokine production|NK T cell differentiation|adaptive immune response|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|protein phosphorylation|activation of phospholipase C activity|phosphorylation|interferon-gamma production|interleukin-4 production|positive regulation of interferon-gamma production|protein autophosphorylation|T cell receptor signaling pathway|positive regulation of interferon-gamma-mediated signaling pathway|","nucleotide binding|RNA polymerase II regulatory region DNA binding|DNA binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.7,1.04,10,-0.2,0.383,-0.1,0.0566,-0.0566,0.886,0,0,-1.2,1.9
ENSMUSG00000062190,LANCL2,LanC (bacterial lantibiotic synthetase component C)-like 2,nucleus|cytoplasm|cytosol|plasma membrane|membrane|cortical actin cytoskeleton|,"positive regulation of abscisic acid-activated signaling pathway|negative regulation of transcription, DNA-templated|",catalytic activity|phosphatidylinositol-5-phosphate binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-4-phosphate binding|,10,0.1,0.14,10,-0.1,0.295,-0.1,0.0556,-0.0556,0.886,0,0,-0.8,2
ENSMUSG00000029377,EREG,epiregulin,extracellular region|extracellular space|extracellular space|plasma membrane|membrane|integral component of membrane|,"angiogenesis|ovarian cumulus expansion|oocyte maturation|positive regulation of cytokine production|female meiotic division|epidermal growth factor receptor signaling pathway|cell-cell signaling|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|mRNA transcription|anatomical structure morphogenesis|organ morphogenesis|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|cell differentiation|ovulation|positive regulation of cytokine biosynthetic process|positive regulation of phosphorylation|positive regulation of phosphorylation|luteinizing hormone signaling pathway|keratinocyte proliferation|positive regulation of innate immune response|positive regulation of interleukin-6 biosynthetic process|positive regulation of DNA replication|positive regulation of DNA replication|positive regulation of DNA replication|positive regulation of epidermal growth factor-activated receptor activity|positive regulation of epidermal growth factor-activated receptor activity|positive regulation of mitosis|positive regulation of mitosis|positive regulation of mitosis|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|positive regulation of fibroblast proliferation|primary follicle stage|positive regulation of smooth muscle cell proliferation|positive regulation of smooth muscle cell proliferation|negative regulation of smooth muscle cell differentiation|positive regulation of cell division|",epidermal growth factor receptor binding|growth factor activity|,10,0.1,0.234,10,-0.1,0.235,0.1,0.0535,0.0535,0.887,0,0,-1.5,1.4
ENSMUSG00000050395,TNFSF15,"tumor necrosis factor (ligand) superfamily, member 15",extracellular region|extracellular space|plasma membrane|membrane|integral component of membrane|,apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|immune response|signal transduction|activation of NF-kappaB-inducing kinase activity|cytokine metabolic process|positive regulation of cytokine secretion|,death receptor binding|cytokine activity|tumor necrosis factor receptor binding|,10,-0.4,1.54,10,0.1,0.146,-0.1,0.0534,-0.0534,0.887,0,0,-1.8,1
ENSMUSG00000025791,PGM2,phosphoglucomutase 2,cytoplasm|cytosol|extracellular vesicular exosome|,carbohydrate metabolic process|glycogen biosynthetic process|glucose metabolic process|galactose catabolic process|,"magnesium ion binding|phosphoglucomutase activity|phosphoglucomutase activity|isomerase activity|intramolecular transferase activity, phosphotransferases|metal ion binding|",10,0.1,0.047,9,-0.1,0.0783,-0.1,0.0531,-0.0531,0.887,0,0,-1.5,1.6
ENSMUSG00000031535,DKK4,dickkopf homolog 4 (Xenopus laevis),extracellular region|,multicellular organismal development|Wnt signaling pathway|negative regulation of Wnt signaling pathway|,None,10,-0.1,0.134,10,0,0,-0.1,0.0526,-0.0526,0.887,0,0,-1.6,1.4
ENSMUSG00000052957,GAS1,growth arrest specific 1,plasma membrane|plasma membrane|membrane|anchored component of membrane|anchored component of plasma membrane|anchored component of plasma membrane|,positive regulation of mesenchymal cell proliferation|cell cycle|cell cycle arrest|axon guidance|positive regulation of cell proliferation|regulation of smoothened signaling pathway|dorsal/ventral pattern formation|negative regulation of protein processing|programmed cell death|cerebellum morphogenesis|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|negative regulation of cell growth|outer ear morphogenesis|middle ear morphogenesis|odontogenesis|embryonic digit morphogenesis|embryonic digit morphogenesis|camera-type eye development|negative regulation of apoptotic process|negative regulation of apoptotic process|cell fate commitment|cell fate commitment|negative regulation of smoothened signaling pathway|positive regulation of smoothened signaling pathway|positive regulation of smoothened signaling pathway|negative regulation of mitotic cell cycle|developmental growth|eye morphogenesis|embryonic morphogenesis|embryonic morphogenesis|embryonic cranial skeleton morphogenesis|embryonic cranial skeleton morphogenesis|embryonic skeletal system development|embryonic skeletal system development|positive regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|palate development|regulation of ER to Golgi vesicle-mediated transport|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,protein binding|,10,0,0,10,0.2,0.415,0.1,0.0493,0.0493,0.888,0,0,-1,1.9
ENSMUSG00000050751,PGBD5,piggyBac transposable element derived 5,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.539,10,0,0,-0.1,0.0466,-0.0466,0.889,0,0,-1.6,1.4
ENSMUSG00000063820,ARL9,ADP-ribosylation factor-like 9,cellular_component|,biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0,0,10,0.2,0.536,0.1,0.0432,0.0432,0.889,0,0,-0.9,2
ENSMUSG00000029711,EPO,erythropoietin,extracellular region|extracellular space|extracellular space|cell surface|,"angiogenesis|response to hypoxia|heart morphogenesis|regulation of transcription from RNA polymerase II promoter|apoptotic process|embryo implantation|positive regulation of cell proliferation|negative regulation of calcium ion transport into cytosol|peptidyl-serine phosphorylation|erythrocyte differentiation|negative regulation of myeloid cell apoptotic process|positive regulation of tyrosine phosphorylation of Stat5 protein|hemoglobin biosynthetic process|negative regulation of apoptotic process|erythrocyte maturation|positive regulation of neuron differentiation|positive regulation of DNA replication|positive regulation of protein kinase activity|positive regulation of transcription, DNA-templated|positive regulation of Ras protein signal transduction|cardiac muscle tissue morphogenesis|ventricular cardiac muscle tissue morphogenesis|vasculogenesis involved in coronary vascular morphogenesis|visceral serous pericardium development|cellular hyperosmotic response|negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|negative regulation of erythrocyte apoptotic process|negative regulation of cation channel activity|",erythropoietin receptor binding|hormone activity|protein kinase activator activity|,10,-0.7,0.42,10,0.2,0.26,0.1,0.0394,0.0394,0.891,0,0,-1.8,1.3
ENSMUSG00000020460,RPS27A,ribosomal protein S27A,intracellular|nucleus|cytoplasm|ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|biological_process|,structural constituent of ribosome|poly(A) RNA binding|metal ion binding|,4,-0.1,0.0274,5,0.3,0.342,0.3,0.0362,0.0362,0.892,0,0,-1.4,2
ENSMUSG00000030271,OGG1,8-oxoguanine DNA-glycosylase 1,nucleus|nucleus|nucleoplasm|mitochondrion|mitochondrion|mitochondrion|nuclear matrix|nuclear speck|,"DNA catabolic process, endonucleolytic|DNA catabolic process, endonucleolytic|DNA repair|DNA repair|base-excision repair|base-excision repair|base-excision repair|nucleotide-excision repair|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|response to oxidative stress|aging|metabolic process|response to radiation|response to estradiol|regulation of protein import into nucleus, translocation|negative regulation of apoptotic process|","purine-specific mismatch base pair DNA N-glycosylase activity|oxidized base lesion DNA N-glycosylase activity|damaged DNA binding|catalytic activity|DNA-(apurinic or apyrimidinic site) lyase activity|uracil DNA N-glycosylase activity|microtubule binding|oxidized purine nucleobase lesion DNA N-glycosylase activity|oxidized purine nucleobase lesion DNA N-glycosylase activity|oxidized purine nucleobase lesion DNA N-glycosylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|lyase activity|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA N-glycosylase activity|8-oxo-7,8-dihydroguanine DNA N-glycosylase activity|DNA-3-methylbase glycosylase activity|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0,0,10,0.2,0.244,0.1,0.0346,0.0346,0.892,0,0,-1.8,1.3
ENSMUSG00000029229,CHIC2,cysteine-rich hydrophobic domain 2,intracellular|cell|Golgi apparatus|Golgi-associated vesicle|plasma membrane|membrane|,Golgi to plasma membrane transport|,molecular_function|,9,0,0,9,-0.3,0.227,-0.3,0.0345,-0.0345,0.892,0,0,-1.8,1.3
ENSMUSG00000016386,MPPED2,metallophosphoesterase domain containing 2,cellular_component|,biological_process|,nuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0,0,10,0.1,0.328,0.1,0.0336,0.0336,0.892,0,0,-1.4,1.5
ENSMUSG00000041710,TRPC5,"transient receptor potential cation channel, subfamily C, member 5",plasma membrane|membrane|integral component of membrane|calcium channel complex|,transport|ion transport|calcium ion transport|transmembrane transport|calcium ion transmembrane transport|,"ion channel activity|calcium channel activity|protein binding|inositol 1,4,5 trisphosphate binding|",10,0.2,0.349,10,-0.5,1.3,-0.1,0.0332,-0.0332,0.893,0,0,-1.8,1.1
ENSMUSG00000021281,TNFAIP2,"tumor necrosis factor, alpha-induced protein 2",exocyst|,angiogenesis|exocytosis|multicellular organismal development|cell differentiation|,None,10,-0.3,1.9,10,0.1,0.33,-0.1,0.0325,-0.0325,0.893,0,0,-1.7,1.1
ENSMUSG00000042417,CCNO,cyclin O,nucleus|nucleoplasm|,regulation of cyclin-dependent protein serine/threonine kinase activity|base-excision repair|cell cycle|cell division|regulation of cell cycle|,uracil DNA N-glycosylase activity|protein kinase binding|,10,0.1,0.0508,10,-0.4,1.36,-0.1,0.03,-0.03,0.894,0,0,-1.9,1
ENSMUSG00000032554,TRF,transferrin,extracellular region|basement membrane|extracellular space|endosome|early endosome|early endosome|late endosome|coated pit|coated pit|basal plasma membrane|cell surface|cytoplasmic membrane-bounded vesicle|apical plasma membrane|vesicle coat|endocytic vesicle|endocytic vesicle|basal part of cell|perinuclear region of cytoplasm|recycling endosome|recycling endosome|extracellular vesicular exosome|blood microparticle|dense body|,"transport|ion transport|iron ion transport|cellular iron ion homeostasis|actin filament organization|activation of JUN kinase activity|ferric iron transport|osteoclast differentiation|positive regulation of myelination|iron ion transmembrane transport|positive regulation of phosphorylation|positive regulation of bone resorption|positive regulation of transcription, DNA-templated|iron ion homeostasis|SMAD protein signal transduction|ERK1 and ERK2 cascade|positive regulation of oligodendrocyte progenitor proliferation|positive regulation of cell motility|",protein binding|ferric iron binding|ferric iron transmembrane transporter activity|metal ion binding|,10,0,0,10,0.1,0.0519,0.1,0.0277,0.0277,0.894,0,0,-1.5,1.5
ENSMUSG00000009112,BCL2L13,BCL2-like 13 (apoptosis facilitator),mitochondrion|membrane|integral component of membrane|integral component of membrane|,apoptotic process|regulation of apoptotic process|,molecular_function|,10,0.1,0.139,10,0,0,-0.1,0.0255,-0.0255,0.895,0,0,-1.5,1.4
ENSMUSG00000003500,IMPDH1,inosine 5'-phosphate dehydrogenase 1,nucleus|cytoplasm|,purine nucleotide biosynthetic process|GMP biosynthetic process|lymphocyte proliferation|oxidation-reduction process|,nucleic acid binding|DNA binding|catalytic activity|IMP dehydrogenase activity|oxidoreductase activity|adenyl nucleotide binding|metal ion binding|,10,0.1,0.0286,10,0.3,0.0815,0.1,0.0211,0.0211,0.896,0,0,-1.1,1.8
ENSMUSG00000027272,UBR1,ubiquitin protein ligase E3 component n-recognin 1,ubiquitin ligase complex|proteasome complex|cytoplasm|,ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|protein ubiquitination|protein catabolic process|negative regulation of TOR signaling|cellular response to leucine|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|leucine binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.7,0.205,-0.1,0.0198,-0.0198,0.897,0,0,-1.1,1.8
ENSMUSG00000024526,CIDEA,"cell death-inducing DNA fragmentation factor, alpha subunit-like effector A",intracellular|nucleus|cytoplasm|mitochondrion|mitochondrial envelope|lipid particle|lipid particle|,"temperature homeostasis|transcription, DNA-templated|regulation of transcription, DNA-templated|lipid metabolic process|apoptotic process|cell death|positive regulation of sequestering of triglyceride|lipid storage|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of tumor necrosis factor production|negative regulation of cytokine secretion|negative regulation of lipid catabolic process|negative regulation of lipid catabolic process|negative regulation of execution phase of apoptosis|regulation of apoptotic DNA fragmentation|",protein binding|protein homodimerization activity|,10,-0.1,0.0591,10,0,0,-0.1,0.0195,-0.0195,0.897,0,0,-1.9,1
ENSMUSG00000050926,DCAF12L2,DDB1 and CUL4 associated factor 12-like 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.641,-0.1,0.0195,-0.0195,0.897,0,0,-1.8,1.1
ENSMUSG00000026815,GFI1B,growth factor independent 1B,nucleus|transcription factor complex|nuclear matrix|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of granulocyte differentiation|regulation of erythrocyte differentiation|negative regulation of histone H3-K4 methylation|positive regulation of histone H3-K9 methylation|",RNA polymerase II transcription factor binding|nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,0,0,10,1.9,2.11,-0.1,0.0156,-0.0156,0.898,0,0,-2,2.7
ENSMUSG00000060675,PLA2G16,"phospholipase A2, group XVI",cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|perinuclear region of cytoplasm|,lipid metabolic process|phospholipid metabolic process|phospholipid biosynthetic process|lipid catabolic process|negative regulation of cell cycle|,phospholipase A2 activity|phospholipase A2 activity|phosphatidylcholine 1-acylhydrolase activity|hydrolase activity|phosphatidylserine 1-acylhydrolase activity|1-acyl-2-lysophosphatidylserine acylhydrolase activity|,10,0,0,10,0.2,0.523,0.1,0.0146,0.0146,0.898,0,0,-1.3,1.6
ENSMUSG00000050377,IL31RA,interleukin 31 receptor A,plasma membrane|membrane|integral component of membrane|,immune system process|positive regulation of cell proliferation|cytokine-mediated signaling pathway|,cytokine receptor activity|,9,-0.7,0.0912,10,-0.3,0.294,-0.4,0.0138,-0.0138,0.898,0,0,-1.9,0.9
ENSMUSG00000058152,CHSY3,chondroitin sulfate synthase 3,cellular_component|Golgi apparatus|membrane|integral component of membrane|Golgi cisterna membrane|,biological_process|,molecular_function|acetylgalactosaminyltransferase activity|transferase activity|metal ion binding|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity|,10,-0.1,0.219,10,0,0,-0.1,0.0105,-0.0105,0.899,0,0,-1.3,1.6
ENSMUSG00000037771,SLC32A1,"solute carrier family 32 (GABA vesicular transporter), member 1",integral component of plasma membrane|synaptic vesicle|membrane|integral component of membrane|dendrite|cytoplasmic vesicle|neuron projection|neuron projection|intracellular organelle|dendrite terminus|neuron projection terminus|neuron projection terminus|cone cell pedicle|synapse|cell tip|inhibitory synapse|inhibitory synapse|,transport|neurotransmitter transport|gamma-aminobutyric acid transport|glycine transport|proton transport|sodium ion transmembrane transport|L-alpha-amino acid transmembrane transport|,glycine transmembrane transporter activity|gamma-aminobutyric acid:proton symporter activity|,10,0,0,10,0.1,0.151,-0.1,0.00926,-0.00926,0.9,0,0,-1.1,1.8
ENSMUSG00000022525,HRASLS,HRAS-like suppressor,intracellular|nuclear envelope lumen|cytoplasm|peroxisome|membrane|integral component of membrane|,regulation of cell growth|lipid metabolic process|peroxisome organization|Ras protein signal transduction|lipid catabolic process|ether lipid metabolic process|,"dihydrolipoamide branched chain acyltransferase activity|phospholipase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|prenylcysteine methylesterase activity|lipase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|hydrolase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|endosulfan lactone lactonase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-ascorbate 6-phosphate lactonase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|azetidine-2-carboxylic acid acetyltransferase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|peptidyl-lysine N-acetyltransferase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.6,0.8,10,0,0,0.1,0.00869,0.00869,0.9,0,0,-0.8,1.9
ENSMUSG00000026435,SLC45A3,"solute carrier family 45, member 3",cellular_component|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0,0,10,0.1,0.109,0.1,0.00829,0.00829,0.9,0,0,-1.3,1.7
ENSMUSG00000021365,NEDD9,"neural precursor cell expressed, developmentally down-regulated gene 9",spindle pole|nucleus|cytoplasm|cytoskeleton|,cell cycle|mitotic nuclear division|cell adhesion|regulation of growth|cell division|,None,10,0,0,10,0.3,0.187,0.1,0.00422,0.00422,0.901,0,0,-1.7,1.3
ENSMUSG00000044641,PARD6B,par-6 family cell polarity regulator beta,nucleus|cytoplasm|plasma membrane|tight junction|tight junction|cell cortex|membrane|cell junction|protein complex|apical part of cell|extracellular vesicular exosome|,protein complex assembly|cell cycle|cell division|,protein binding|,10,-0.1,0.217,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000026586,PRRX1,paired related homeobox 1,nucleus|nucleus|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|positive regulation of mesenchymal cell proliferation|regulation of transcription, DNA-templated|multicellular organismal development|embryonic limb morphogenesis|inner ear morphogenesis|middle ear morphogenesis|middle ear morphogenesis|positive regulation of smoothened signaling pathway|embryonic cranial skeleton morphogenesis|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|artery morphogenesis|artery morphogenesis|cartilage development|cartilage development|palate development|",DNA binding|sequence-specific DNA binding|HMG box domain binding|,10,0,0,10,-0.1,0.125,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000041020,MAP7D2,MAP7 domain containing 2,cellular_component|microtubule|,microtubule cytoskeleton organization|biological_process|,molecular_function|,10,-0.7,0.19,10,0.3,0.487,0,0,0,0.903,0,0,-1.9,1.2
ENSMUSG00000059498,FCGR3,"Fc receptor, IgG, low affinity III",cell|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,"antibody-dependent cellular cytotoxicity|positive regulation of type IIa hypersensitivity|positive regulation of type III hypersensitivity|positive regulation of type I hypersensitivity|positive regulation of type I hypersensitivity|serotonin secretion|phagocytosis, recognition|phagocytosis, engulfment|cell surface receptor signaling pathway|neutrophil chemotaxis|Fc-gamma receptor signaling pathway|positive regulation of tumor necrosis factor biosynthetic process|antigen processing and presentation of exogenous peptide antigen via MHC class I|mast cell activation|mast cell activation|positive regulation of phagocytosis|regulation of immune response|",IgG receptor activity|IgG receptor activity|IgG binding|,10,0.1,0.197,10,-0.1,0.158,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000035493,TGFBI,"transforming growth factor, beta induced",extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|extracellular space|trans-Golgi network|extracellular matrix|extracellular vesicular exosome|,cell adhesion|extracellular matrix organization|,collagen binding|extracellular matrix binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000005447,PAFAH1B3,"platelet-activating factor acetylhydrolase, isoform 1b, subunit 3",cytoplasm|cytosol|membrane|extracellular vesicular exosome|,lipid metabolic process|spermatogenesis|spermatogenesis|lipid catabolic process|,1-alkyl-2-acetylglycerophosphocholine esterase activity|protein binding|hydrolase activity|protein heterodimerization activity|platelet-activating factor acetyltransferase activity|,10,0,0,10,0.2,0.157,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000058254,TSPAN7,tetraspanin 7,membrane|integral component of membrane|,None,None,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000074968,ANO3,anoctamin 3,cellular_component|plasma membrane|membrane|integral component of membrane|,phospholipid transport|calcium activated phosphatidylcholine scrambling|calcium activated galactosylceramide scrambling|,phospholipid scramblase activity|,10,0.6,0.687,10,-0.4,0.817,0,0,0,0.903,0,0,-1.4,1.7
ENSMUSG00000028552,EPS15,epidermal growth factor receptor pathway substrate 15,cytoplasm|endosome|plasma membrane|plasma membrane|coated pit|membrane|membrane|AP-2 adaptor complex|clathrin coat of coated pit|clathrin-coated vesicle|intracellular membrane-bounded organelle|ciliary membrane|,transport|Golgi to endosome transport|endocytosis|protein transport|clathrin coat assembly|,calcium ion binding|protein binding|SH3 domain binding|polyubiquitin binding|identical protein binding|metal ion binding|,10,0.1,0.0804,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000000142,AXIN2,axin2,nucleus|nucleus|cytoplasm|centrosome|centrosome|cytoplasmic microtubule|plasma membrane|cell cortex|postsynaptic density|cytoplasmic membrane-bounded vesicle|beta-catenin destruction complex|protein complex|,"somitogenesis|positive regulation of protein phosphorylation|intramembranous ossification|secondary heart field specification|chondrocyte differentiation involved in endochondral bone morphogenesis|regulation of transcription, DNA-templated|cell death|cell death|cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|dorsal/ventral axis specification|positive regulation of epithelial to mesenchymal transition|positive regulation of cell death|Wnt signaling pathway|regulation of Wnt signaling pathway|bone mineralization|regulation of mismatch repair|cellular protein localization|regulation of catenin import into nucleus|negative regulation of catenin import into nucleus|termination of G-protein coupled receptor signaling pathway|odontogenesis|positive regulation of GTPase activity|maintenance of DNA repeat elements|negative regulation of osteoblast differentiation|positive regulation of protein kinase activity|mRNA stabilization|regulation of chondrocyte development|regulation of centromeric sister chromatid cohesion|regulation of centromeric sister chromatid cohesion|cellular response to organic cyclic compound|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|Wnt signaling pathway involved in somitogenesis|negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification|",GTPase activator activity|protein binding|beta-catenin binding|beta-catenin binding|enzyme binding|protein kinase binding|protein kinase binding|ubiquitin protein ligase binding|ubiquitin protein ligase binding|armadillo repeat domain binding|I-SMAD binding|,10,0,0,10,-0.1,0.212,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000012819,CDH23,cadherin 23 (otocadherin),photoreceptor inner segment|centrosome|plasma membrane|membrane|integral component of membrane|stereocilium|stereocilium bundle tip|apical part of cell|synapse|kinocilium|,calcium ion transport|cell adhesion|homophilic cell adhesion|sensory perception of sound|sensory perception of sound|sensory perception of sound|locomotory behavior|adult locomotory behavior|calcium-dependent cell-cell adhesion|inner ear morphogenesis|auditory receptor cell differentiation|photoreceptor cell maintenance|post-embryonic organ morphogenesis|inner ear development|sensory perception of light stimulus|sensory perception of light stimulus|equilibrioception|cytosolic calcium ion homeostasis|righting reflex|auditory receptor cell stereocilium organization|auditory receptor cell stereocilium organization|,calcium ion binding|protein binding|metal ion binding|protein N-terminus binding|,10,-1.3,1.24,10,0.2,0.448,0,0,0,0.903,0,0,-2,0.8
ENSMUSG00000055322,TNS1,tensin 1,focal adhesion|focal adhesion|cell-substrate junction|,cell-substrate junction assembly|fibroblast migration|,actin binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.8
ENSMUSG00000053852,GPR112,G protein-coupled receptor 112,plasma membrane|membrane|integral component of membrane|,None,None,10,-0.7,0.011,10,0.1,0.175,0,0,0,0.903,0,0,-2,1
ENSMUSG00000002489,TIAM1,T cell lymphoma invasion and metastasis 1,intracellular|plasma membrane|cell-cell junction|membrane|cell junction|extrinsic component of cytoplasmic side of plasma membrane|cell-cell contact zone|,cell-matrix adhesion|signal transduction|small GTPase mediated signal transduction|positive regulation of neuron projection development|cell migration|Rac protein signal transduction|brain-derived neurotrophic factor receptor signaling pathway|regulation of Rac GTPase activity|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of GTPase activity|ephrin receptor signaling pathway|positive regulation of axonogenesis|,receptor signaling protein activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|phospholipid binding|lipid binding|Rac guanyl-nucleotide exchange factor activity|receptor tyrosine kinase binding|ephrin receptor binding|,10,-0.1,0.38,10,0,0,0,0,0,0.903,0,0,-1.5,1.6
ENSMUSG00000019917,10-Sep,septin 10,cellular_component|cytoplasm|cytoskeleton|septin complex|,cell cycle|biological_process|cell division|,nucleotide binding|molecular_function|GTP binding|,10,-0.2,0.272,10,0,0,0,0,0,0.903,0,0,-2,0.9
ENSMUSG00000044499,HS3ST5,heparan sulfate (glucosamine) 3-O-sulfotransferase 5,cellular_component|Golgi apparatus|membrane|integral component of membrane|,"protein sulfation|heparan sulfate proteoglycan biosynthetic process, enzymatic modification|regulation of viral entry into host cell|negative regulation of coagulation|",sulfotransferase activity|[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity|transferase activity|,9,0.4,0.92,10,0,0,0,0,0,0.903,0,0,-0.8,2
ENSMUSG00000026617,BPNT1,bisphosphate 3'-nucleotidase 1,extracellular vesicular exosome|,dephosphorylation|dephosphorylation|phosphatidylinositol phosphorylation|,"magnesium ion binding|inositol-1,4-bisphosphate 1-phosphatase activity|3'(2'),5'-bisphosphate nucleotidase activity|3'(2'),5'-bisphosphate nucleotidase activity|hydrolase activity|metal ion binding|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000030083,ABTB1,ankyrin repeat and BTB (POZ) domain containing 1,nucleolus|cytoplasm|plasma membrane|,translation|translational elongation|biological_process|,molecular_function|translation elongation factor activity|,10,0,0,10,0.1,0.102,0,0,0,0.903,0,0,-1.4,1.7
ENSMUSG00000037974,MUC5AC,"mucin 5, subtypes A and C, tracheobronchial/gastric",extracellular region|extracellular space|fibril|extracellular vesicular exosome|,extracellular fibril organization|,protein binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.8
ENSMUSG00000031253,SRPX2,"sushi-repeat-containing protein, X-linked 2",extracellular region|extracellular space|cytoplasm|cell surface|cell junction|synapse|excitatory synapse|synaptic membrane|,angiogenesis|cell adhesion|single organismal cell-cell adhesion|regulation of phosphorylation|cell motility|positive regulation of synapse assembly|vocalization behavior|positive regulation of cell migration involved in sprouting angiogenesis|,receptor binding|receptor binding|hepatocyte growth factor binding|identical protein binding|,10,1.5,2.38,10,-0.1,0.0953,0,0,0,0.903,0,0,-0.6,3
ENSMUSG00000038227,HOXA9,homeobox A9,nucleus|nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|single fertilization|male gonad development|anterior/posterior pattern specification|anterior/posterior pattern specification|proximal/distal pattern formation|regulation of gene expression|mammary gland development|embryonic forelimb morphogenesis|endothelial cell activation|negative regulation of myeloid cell differentiation|embryonic skeletal system development|embryonic skeletal system development|uterus development|definitive hemopoiesis|",DNA binding|protein binding|enzyme binding|sequence-specific DNA binding|,10,0,0,10,0.1,0.137,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000020181,NAV3,neuron navigator 3,nucleus|nuclear envelope|membrane|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0.1,0.137,9,0,0,0,0,0,0.903,0,0,-1.3,1.8
ENSMUSG00000027716,TRPC3,"transient receptor potential cation channel, subfamily C, member 3",membrane|integral component of membrane|,transport|ion transport|calcium ion transport|positive regulation of calcium ion transport into cytosol|response to ATP|response to calcium ion|transmembrane transport|calcium ion transmembrane transport|,"ion channel activity|calcium activated cation channel activity|calcium channel activity|inositol 1,4,5 trisphosphate binding|",10,-0.1,0.339,10,0.1,0.121,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000028080,LRBA,LPS-responsive beige-like anchor,intracellular|cell|lysosome|endoplasmic reticulum|Golgi apparatus|trans-Golgi network|plasma membrane|membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|,signal transduction|protein localization|endosomal transport|,protein kinase A binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000051177,PLCB1,"phospholipase C, beta 1",nuclear chromatin|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|cytosol|membrane|nuclear speck|nuclear speck|extracellular vesicular exosome|,"G2/M transition of mitotic cell cycle|G2/M transition of mitotic cell cycle|oocyte maturation|mRNA processing|lipid metabolic process|cell adhesion|signal transduction|G-protein coupled acetylcholine receptor signaling pathway|glutamate receptor signaling pathway|brain development|memory|regulation of G-protein coupled receptor protein signaling pathway|insulin receptor signaling pathway|lipid catabolic process|cerebral cortex development|erythrocyte differentiation|macrophage differentiation|positive regulation of sodium:proton antiporter activity|positive regulation of interleukin-12 production|response to monosaccharide|intracellular signal transduction|interleukin-12-mediated signaling pathway|interleukin-15-mediated signaling pathway|positive regulation of embryonic development|response to peptide hormone|positive regulation of GTPase activity|fat cell differentiation|positive regulation of myoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of JNK cascade|insulin-like growth factor receptor signaling pathway|positive regulation of developmental growth|regulation of cell cycle|activation of meiosis involved in egg activation|interleukin-1-mediated signaling pathway|regulation of fertilization|positive regulation of G1/S transition of mitotic cell cycle|positive regulation of acrosome reaction|negative regulation of monocyte extravasation|positive regulation of CD24 biosynthetic process|","phosphatidylinositol phospholipase C activity|phosphatidylinositol phospholipase C activity|signal transducer activity|GTPase activator activity|calcium ion binding|protein binding|calmodulin binding|lamin binding|phosphatidylinositol-4,5-bisphosphate binding|phosphoric diester hydrolase activity|hydrolase activity|enzyme binding|protein homodimerization activity|",10,0.1,0.0648,10,0,0,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000038203,HOXA13,homeobox A13,nucleus|nucleus|intermediate filament cytoskeleton|,"vasculogenesis|endothelial cell morphogenesis|tissue homeostasis|ventricular septum development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anatomical structure morphogenesis|organ morphogenesis|regulation of BMP signaling pathway|male genitalia development|embryonic forelimb morphogenesis|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|inner ear development|artery morphogenesis|branching involved in prostate gland morphogenesis|endothelial cell fate specification|positive regulation of mesenchymal cell apoptotic process|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.2,0.638,10,-0.2,1.02,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000021466,PTCH1,patched homolog 1,extracellular region|Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|caveola|postsynaptic density|membrane|integral component of membrane|midbody|intracellular membrane-bounded organelle|dendritic growth cone|axonal growth cone|perinuclear region of cytoplasm|primary cilium|,negative regulation of transcription from RNA polymerase II promoter|branching involved in ureteric bud morphogenesis|in utero embryonic development|neural tube formation|neural tube closure|heart morphogenesis|signal transduction|signal transduction|smoothened signaling pathway|smoothened signaling pathway|regulation of mitotic cell cycle|pattern specification process|brain development|negative regulation of cell proliferation|epidermis development|regulation of smoothened signaling pathway|regulation of smoothened signaling pathway|organ morphogenesis|dorsal/ventral pattern formation|response to chlorate|positive regulation of cholesterol efflux|protein processing|spinal cord motor neuron differentiation|neural tube patterning|dorsal/ventral neural tube patterning|neural plate axis specification|embryonic limb morphogenesis|embryonic limb morphogenesis|mammary gland development|regulation of protein localization|regulation of protein localization|limb morphogenesis|hindlimb morphogenesis|regulation of growth|negative regulation of multicellular organism growth|regulation of cell proliferation|glucose homeostasis|negative regulation of sequence-specific DNA binding transcription factor activity|keratinocyte proliferation|negative regulation of osteoblast differentiation|negative regulation of smoothened signaling pathway|negative regulation of smoothened signaling pathway|negative regulation of smoothened signaling pathway|embryonic organ development|negative regulation of epithelial cell proliferation|negative regulation of cell division|pharyngeal system development|mammary gland duct morphogenesis|mammary gland epithelial cell differentiation|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|cell differentiation involved in kidney development|somite development|somite development|cellular response to cholesterol|cell proliferation involved in metanephros development|protein targeting to plasma membrane|,patched binding|smoothened binding|protein binding|hedgehog receptor activity|heparin binding|zinc ion binding|cholesterol binding|cholesterol binding|cyclin binding|cyclin binding|protein complex binding|hedgehog family protein binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-2,1.1
ENSMUSG00000000682,CD52,CD52 antigen,plasma membrane|membrane|anchored component of membrane|,None,None,10,0.2,0.125,10,0,0,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000053141,PTPRT,"protein tyrosine phosphatase, receptor type, T",plasma membrane|cell surface|membrane|integral component of membrane|,protein dephosphorylation|protein dephosphorylation|homophilic cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|dephosphorylation|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|beta-catenin binding|beta-catenin binding|hydrolase activity|thiolester hydrolase activity|phosphatase activity|alpha-catenin binding|alpha-catenin binding|gamma-catenin binding|gamma-catenin binding|cadherin binding|cadherin binding|alpha-actinin binding|delta-catenin binding|delta-catenin binding|,10,0.1,0.178,10,-0.1,0.242,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000047517,DMBT1,deleted in malignant brain tumors 1,extracellular region|proteinaceous extracellular matrix|extracellular space|intracellular|cytoplasm|membrane|integral component of membrane|extrinsic component of membrane|phagocytic vesicle membrane|extracellular matrix|cytoplasmic vesicle|zymogen granule membrane|extracellular vesicular exosome|,blastocyst development|inner cell mass cell proliferation|transport|multicellular organismal development|protein transport|cell differentiation|positive regulation of epithelial cell differentiation|,scavenger receptor activity|protein binding|zymogen binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000031523,DLC1,deleted in liver cancer 1,stress fiber|intracellular|nucleus|cytoplasm|actin filament|caveola|focal adhesion|focal adhesion|membrane|cell junction|membrane raft|,neural tube closure|heart morphogenesis|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cytoskeleton organization|signal transduction|activation of phospholipase C activity|negative regulation of cell proliferation|regulation of cell shape|hindbrain morphogenesis|actin cytoskeleton organization|negative regulation of cell migration|forebrain development|positive regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|regulation of Rho protein signal transduction|negative regulation of Rho protein signal transduction|positive regulation of protein dephosphorylation|focal adhesion assembly|negative regulation of stress fiber assembly|positive regulation of execution phase of apoptosis|,GTPase activator activity|Rho GTPase activator activity|lipid binding|vinculin binding|SH2 domain binding|phospholipase binding|,10,-0.1,0.323,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000021376,TPMT,thiopurine methyltransferase,cytoplasm|extracellular vesicular exosome|,methylation|,thiopurine S-methyltransferase activity|thiopurine S-methyltransferase activity|methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|transferase activity|,10,-0.1,0.216,10,0.6,1.55,0,0,0,0.903,0,0,-0.8,1.9
ENSMUSG00000032487,PTGS2,prostaglandin-endoperoxide synthase 2,cytoplasm|cytoplasm|endoplasmic reticulum|caveola|membrane|neuron projection|neuron projection|intracellular membrane-bounded organelle|protein complex|,"prostaglandin biosynthetic process|prostaglandin biosynthetic process|angiogenesis|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|inflammatory response|response to oxidative stress|embryo implantation|learning|memory|regulation of blood pressure|positive regulation of cell proliferation|negative regulation of cell proliferation|positive regulation vascular endothelial growth factor production|positive regulation of cell death|sensory perception of pain|cyclooxygenase pathway|cyclooxygenase pathway|keratinocyte differentiation|bone mineralization|ovulation|positive regulation of fever generation|positive regulation of fever generation|positive regulation of synaptic plasticity|negative regulation of synaptic transmission, dopaminergic|response to lipopolysaccharide|response to cytokine|maintenance of blood-brain barrier|regulation of cell proliferation|positive regulation of NF-kappaB import into nucleus|anagen|positive regulation of apoptotic process|positive regulation of nitric oxide biosynthetic process|negative regulation of cell cycle|positive regulation of vasoconstriction|negative regulation of smooth muscle contraction|positive regulation of smooth muscle contraction|decidualization|positive regulation of smooth muscle cell proliferation|brown fat cell differentiation|negative regulation of calcium ion transport|positive regulation of synaptic transmission, glutamatergic|oxidation-reduction process|positive regulation of transforming growth factor beta production|positive regulation of cell migration involved in sprouting angiogenesis|positive regulation of fibroblast growth factor production|positive regulation of brown fat cell differentiation|positive regulation of platelet-derived growth factor production|","peroxidase activity|prostaglandin-endoperoxide synthase activity|prostaglandin-endoperoxide synthase activity|lipid binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|enzyme binding|heme binding|protein homodimerization activity|metal ion binding|dioxygenase activity|",10,0,0,10,-0.2,0.864,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000045532,C1QL1,"complement component 1, q subcomponent-like 1",extracellular region|collagen trimer|cytoplasm|,biological_process|,protein binding|,10,-0.2,0.47,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000006369,FBLN1,fibulin 1,extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|extracellular matrix|extracellular vesicular exosome|,positive regulation of peptidase activity|extracellular matrix organization|,calcium ion binding|protein binding|peptidase activator activity|,10,0,0,10,-0.2,0.424,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000028640,TFAP2C,"transcription factor AP-2, gamma",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|trophectodermal cell differentiation|hair follicle development|keratinocyte development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|stem cell maintenance|stem cell maintenance|forebrain neuron fate commitment|cerebral cortex development|cell differentiation|germ-line stem cell maintenance|somatic stem cell maintenance|skin development|regulation of epidermis development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|sebaceous gland development|dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis|epithelial cell proliferation involved in mammary gland duct elongation|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein dimerization activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.7,1.4
ENSMUSG00000078817,NLRP12,"NLR family, pyrin domain containing 12",cytoplasm|,release of cytoplasmic sequestered NF-kappaB|negative regulation of signal transduction|negative regulation of protein autophosphorylation|negative regulation of NF-kappaB transcription factor activity|dendritic cell migration|regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of MHC class I biosynthetic process|negative regulation of interleukin-6 biosynthetic process|negative regulation of Toll signaling pathway|negative regulation of cytokine secretion|negative regulation of interleukin-1 secretion|negative regulation of inflammatory response|negative regulation of ERK1 and ERK2 cascade|cellular response to cytokine stimulus|negative regulation of NIK/NF-kappaB signaling|,nucleotide binding|protein binding|ATP binding|,10,0.2,0.289,9,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000019848,POPDC3,popeye domain containing 3,membrane|integral component of membrane|,regulation of membrane potential|,None,10,0,0,10,0,0,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000015134,ALDH1A3,"aldehyde dehydrogenase family 1, subfamily A3",cytoplasm|cytoplasm|,optic cup morphogenesis involved in camera-type eye development|retinoic acid biosynthetic process|retinoic acid biosynthetic process|locomotory behavior|metabolic process|nucleus accumbens development|embryonic camera-type eye development|inner ear morphogenesis|retinoic acid metabolic process|retinoic acid metabolic process|retinoic acid metabolic process|retinal metabolic process|positive regulation of apoptotic process|positive regulation of apoptotic process|embryonic eye morphogenesis|embryonic eye morphogenesis|positive regulation of retinoic acid receptor signaling pathway|neuromuscular process controlling balance|oxidation-reduction process|righting reflex|olfactory pit development|face development|,"retinal dehydrogenase activity|3-chloroallyl aldehyde dehydrogenase activity|aldehyde dehydrogenase (NAD) activity|aldehyde dehydrogenase [NAD(P)+] activity|aldehyde dehydrogenase [NAD(P)+] activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|protein homodimerization activity|thyroid hormone binding|NAD+ binding|",10,-0.1,0.117,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000036968,CNPY4,canopy 4 homolog (zebrafish),cellular_component|extracellular region|,regulation of protein localization|,receptor binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-2,1.1
ENSMUSG00000023277,TWF2,"twinfilin, actin-binding protein, homolog 2 (Drosophila)",intracellular|cytoplasm|cytoskeleton|myofibril|lamellipodium|filopodium|growth cone|stereocilium|cell projection|perinuclear region of cytoplasm|extracellular vesicular exosome|,multicellular organismal development|positive regulation of lamellipodium assembly|positive regulation of neuron projection development|cell projection organization|negative regulation of actin filament polymerization|regulation of microvillus length|regulation of actin cytoskeleton organization|intracellular signal transduction|sequestering of actin monomers|positive regulation of axon extension|barbed-end actin filament capping|cellular response to retinoic acid|cellular response to growth factor stimulus|,"actin binding|actin monomer binding|protein kinase C binding|protein kinase C binding|ATP binding|ATP binding|phosphatidylinositol-4,5-bisphosphate binding|poly(A) RNA binding|",10,0,0,10,0.1,0.201,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000075012,FJX1,four jointed box 1 (Drosophila),extracellular region|extracellular space|,retina layer formation|,None,10,0,0,10,0,0,0,0,0,0.903,0,0,-2,1.1
ENSMUSG00000008892,VDAC3,voltage-dependent anion channel 3,nucleus|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|rough endoplasmic reticulum|membrane|integral component of membrane|pore complex|extracellular vesicular exosome|,behavioral fear response|transport|ion transport|anion transport|synaptic transmission|neuron-neuron synaptic transmission|learning|regulation of anion transport|transmembrane transport|,nucleotide binding|voltage-gated anion channel activity|porin activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000051146,CAMK2N2,calcium/calmodulin-dependent protein kinase II inhibitor 2,cellular_component|nucleus|cytoplasm|,negative regulation of protein kinase activity|negative regulation of protein kinase activity|phosphorylation|,protein kinase inhibitor activity|calcium-dependent protein kinase inhibitor activity|calcium-dependent protein kinase inhibitor activity|kinase activity|transferase activity|protein kinase binding|,10,1.1,1.92,10,0,0,0,0,0,0.903,0,0,-1.3,2
ENSMUSG00000037159,WEE2,WEE1 homolog 2 (S. pombe),nucleus|nucleus|cytoplasm|cytoplasm|,protein phosphorylation|mitotic nuclear division|meiotic nuclear division|female meiotic division|phosphorylation|peptidyl-tyrosine phosphorylation|female pronucleus assembly|negative regulation of cyclin-dependent protein serine/threonine kinase activity|regulation of meiosis I|negative regulation of oocyte maturation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.2,0.739,10,1.4,2.22,0,0,0,0.903,0,0,-0.6,2
ENSMUSG00000031490,EIF4EBP1,eukaryotic translation initiation factor 4E binding protein 1,nucleus|cytoplasm|cytoplasm|protein complex|,G1/S transition of mitotic cell cycle|regulation of translation|regulation of translational initiation|insulin receptor signaling pathway|negative regulation of translation|negative regulation of protein complex assembly|TOR signaling|positive regulation of mitotic cell cycle|negative regulation of translational initiation|negative regulation of translational initiation|,protein binding|eukaryotic initiation factor 4E binding|eukaryotic initiation factor 4E binding|translation repressor activity|translation repressor activity|translation initiation factor binding|,10,-0.2,0.856,10,0,0,0,0,0,0.903,0,0,-1.6,1.3
ENSMUSG00000027962,VCAM1,vascular cell adhesion molecule 1,podosome|extracellular space|early endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|microvillus|external side of plasma membrane|cell surface|membrane|integral component of membrane|filopodium|anchored component of membrane|sarcolemma|apical part of cell|extracellular vesicular exosome|alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex|cell periphery|,cell adhesion|cell adhesion|heterophilic cell-cell adhesion|heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|leukocyte cell-cell adhesion|heart development|amine metabolic process|viral process|single organismal cell-cell adhesion|positive regulation of T cell proliferation|oxidation-reduction process|cell chemotaxis|embryonic placenta morphogenesis|chorio-allantoic fusion|visceral serous pericardium development|cellular response to glucose stimulus|,integrin binding|primary amine oxidase activity|cell adhesion molecule binding|,10,0.1,0.0704,10,0,0,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000050836,NTNG1,netrin G1,plasma membrane|membrane|anchored component of membrane|anchored component of plasma membrane|,multicellular organismal development|nervous system development|axonogenesis|cell differentiation|,protein binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.4,1.7
ENSMUSG00000059991,NPTX2,neuronal pentraxin 2,extracellular region|,None,metal ion binding|,10,0.2,0.273,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000024835,CORO1B,"coronin, actin binding protein 1B",stress fiber|cytoplasm|cytoskeleton|actin filament|actin cytoskeleton|lamellipodium|cell leading edge|extracellular vesicular exosome|,cell migration|actin cytoskeleton organization|ruffle organization|negative regulation of Arp2/3 complex-mediated actin nucleation|endothelial cell chemotaxis|wound healing|actin filament bundle assembly|actin filament branching|protein localization to cell leading edge|positive regulation of lamellipodium morphogenesis|,actin binding|protein binding|identical protein binding|actin filament binding|actin filament binding|Arp2/3 complex binding|,10,-0.1,0.0347,10,0,0,0,0,0,0.903,0,0,-1.8,1.3
ENSMUSG00000042499,HOXD11,homeobox D11,nucleus|,"skeletal system development|skeletal system development|metanephros development|branching involved in ureteric bud morphogenesis|organ induction|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|single fertilization|pattern specification process|anterior/posterior pattern specification|dorsal/ventral pattern formation|proximal/distal pattern formation|regulation of gene expression|positive regulation of cell development|embryonic limb morphogenesis|regulation of chondrocyte differentiation|positive regulation of chondrocyte differentiation|embryonic forelimb morphogenesis|embryonic digit morphogenesis|developmental growth|embryonic skeletal joint morphogenesis|cartilage development involved in endochondral bone morphogenesis|",DNA binding|sequence-specific DNA binding|,10,0,0,10,-0.2,0.163,0,0,0,0.903,0,0,-1.7,1.2
ENSMUSG00000053965,PDE5A,"phosphodiesterase 5A, cGMP-specific",cytosol|,regulation of the force of heart contraction|positive regulation of chronic inflammatory response|signal transduction|short-term memory|metabolic process|positive regulation of cardiac muscle hypertrophy|negative regulation of T cell proliferation|positive regulation of apoptotic process|positive regulation of MAP kinase activity|positive regulation of G-protein coupled receptor protein signaling pathway|positive regulation of vasoconstriction|cGMP metabolic process|cGMP catabolic process|cGMP catabolic process|negative regulation of cardiac muscle contraction|relaxation of cardiac muscle|positive regulation of oocyte development|positive regulation of oocyte development|,"nucleotide binding|catalytic activity|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|cGMP binding|metal ion binding|3',5'-cyclic-GMP phosphodiesterase activity|",8,0,0,8,0.1,0.141,0,0,0,0.903,0,0,-1.4,1.7
ENSMUSG00000031329,TSX,testis specific X-linked gene,nucleus|cytoplasm|,male gonad development|fertilization|adult behavior|,molecular_function|,10,0,0,10,-0.3,0.29,0,0,0,0.903,0,0,-2,0.9
ENSMUSG00000029075,TNFRSF4,"tumor necrosis factor receptor superfamily, member 4",plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,"inflammatory response|inflammatory response|cellular defense response|programmed cell death|positive regulation of B cell proliferation|tumor necrosis factor-mediated signaling pathway|T cell proliferation|regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|regulation of protein kinase activity|negative regulation of transcription, DNA-templated|negative regulation of cytokine secretion|positive regulation of immunoglobulin secretion|negative regulation of activation-induced cell death of T cells|negative regulation of extrinsic apoptotic signaling pathway|",tumor necrosis factor-activated receptor activity|protein binding|,10,-0.2,0.558,10,0.1,0.147,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000031431,TSC22D3,"TSC22 domain family, member 3",nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|response to osmotic stress|negative regulation of skeletal muscle tissue development|negative regulation of activation-induced cell death of T cells|",sequence-specific DNA binding transcription factor activity|MRF binding|,10,0.7,1.28,10,-0.1,0.208,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000028785,HPCA,hippocalcin,None,inner ear development|,actin binding|calcium ion binding|protein binding|metal ion binding|,10,0,0,10,0.1,0.215,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000003882,IL7R,interleukin 7 receptor,external side of plasma membrane|membrane|integral component of membrane|,cell morphogenesis|negative regulation of T cell mediated cytotoxicity|immunoglobulin production|regulation of cell size|regulation of cell size|positive regulation of gene expression|cell growth|T cell differentiation|positive regulation of T cell differentiation in thymus|B cell proliferation|B cell proliferation|lymph node development|homeostasis of number of cells|homeostasis of number of cells|,cytokine receptor activity|,10,0.7,0.584,10,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000019982,MYB,myeloblastosis oncogene,nucleus|,"G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|calcium ion transport|regulation of gene expression|B cell differentiation|positive regulation of T-helper cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|thymus development|embryonic digestive tract development|homeostasis of number of cells|positive regulation of histone H3-K4 methylation|positive regulation of histone H3-K9 methylation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|,10,0,0,10,-1.2,1.58,0,0,0,0.903,0,0,-2,0.9
ENSMUSG00000042745,ID1,inhibitor of DNA binding 1,nucleus|nucleus|cytoplasm|Golgi apparatus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|endothelial cell morphogenesis|transcription, DNA-templated|multicellular organismal development|heart development|BMP signaling pathway|protein destabilization|protein destabilization|collagen metabolic process|negative regulation of apoptotic process|negative regulation of DNA binding|regulation of MAPK cascade|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of osteoblast differentiation|regulation of angiogenesis|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|response to antibiotic|lung morphogenesis|lung vasculature development|",sequence-specific DNA binding transcription factor activity|protein binding|protein dimerization activity|,10,1.7,0.593,10,0,0,0,0,0,0.903,0,0,-0.9,3
ENSMUSG00000048583,IGF2,insulin-like growth factor 2,extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|,ossification|positive regulation of protein phosphorylation|carbohydrate metabolic process|glucose metabolic process|memory|organ morphogenesis|response to organic cyclic compound|exocrine pancreas development|response to nicotine|insulin receptor signaling pathway via phosphatidylinositol 3-kinase|positive regulation of activated T cell proliferation|response to drug|positive regulation of catalytic activity|positive regulation of MAPK cascade|positive regulation of glycogen biosynthetic process|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of insulin receptor signaling pathway|positive regulation of insulin receptor signaling pathway|positive regulation of peptidyl-tyrosine phosphorylation|striated muscle cell differentiation|positive regulation of cell division|positive regulation of protein kinase B signaling|positive regulation of protein serine/threonine kinase activity|positive regulation of steroid hormone biosynthetic process|positive regulation of receptor activity|positive regulation of glycogen (starch) synthase activity|,insulin receptor binding|insulin-like growth factor receptor binding|hormone activity|protein binding|growth factor activity|receptor activator activity|protein serine/threonine kinase activator activity|,10,-0.2,0.0861,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000031285,DCX,doublecortin,intracellular|cytoplasm|microtubule|dendrite|cell projection|neuron projection|neuron projection|,neuron migration|neuron migration|multicellular organismal development|nervous system development|brain development|central nervous system projection neuron axonogenesis|cell differentiation|intracellular signal transduction|axon extension|dendrite morphogenesis|,protein binding|microtubule binding|protein kinase binding|,9,0.8,0.522,10,0,0,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000020275,REL,reticuloendotheliosis oncogene,nucleus|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|,"cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|I-kappaB kinase/NF-kappaB signaling|positive regulation of interleukin-12 biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of neuron death|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.2,0.104,10,0,0,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000057614,GNAI1,"guanine nucleotide binding protein (G protein), alpha inhibiting 1",intracellular|nucleus|cytoplasm|lysosomal membrane|centrosome|heterotrimeric G-protein complex|cytoskeleton|plasma membrane|membrane|midbody|protein complex|membrane raft|extracellular vesicular exosome|,GTP catabolic process|cell cycle|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|negative regulation of synaptic transmission|cell division|,nucleotide binding|GTPase activity|GTPase activity|signal transducer activity|GTP binding|guanyl nucleotide binding|GDP binding|G-protein beta/gamma-subunit complex binding|G-protein coupled serotonin receptor binding|G-protein coupled serotonin receptor binding|GTPase activating protein binding|metal ion binding|,10,0,0,10,1.3,2.44,0,0,0,0.903,0,0,-0.5,2
ENSMUSG00000053175,BCL3,B cell leukemia/lymphoma 3,nucleus|cytoplasm|Bcl3-Bcl10 complex|Bcl3/NF-kappaB2 complex|protein complex|intercellular bridge|,"protein import into nucleus, translocation|follicular dendritic cell differentiation|marginal zone B cell differentiation|humoral immune response mediated by circulating immunoglobulin|germinal center formation|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|I-kappaB kinase/NF-kappaB signaling|response to virus|response to UV-C|antimicrobial humoral response|extracellular matrix organization|DNA damage response, signal transduction by p53 class mediator|positive regulation of interferon-gamma production|T-helper 1 type immune response|negative regulation of tumor necrosis factor biosynthetic process|defense response to bacterium|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|defense response to protozoan|regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|T-helper 2 cell differentiation|positive regulation of interleukin-10 biosynthetic process|negative regulation of interleukin-8 biosynthetic process|positive regulation of translation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|spleen development|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|,10,-0.1,0.00297,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000053626,TLL1,tolloid-like,extracellular region|,proteolysis|multicellular organismal development|cell differentiation|,metalloendopeptidase activity|calcium ion binding|collagen binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.0405,10,-0.2,0.127,0,0,0,0.903,0,0,-1.6,1.3
ENSMUSG00000040860,CROCC,"ciliary rootlet coiled-coil, rootletin",cytoplasm|centrosome|centriole|centriole|cytoskeleton|plasma membrane|actin cytoskeleton|ciliary rootlet|extracellular vesicular exosome|,cell cycle|protein localization|centriole-centriole cohesion|cell projection organization|protein localization to organelle|centrosome organization|,structural molecule activity|kinesin binding|,10,0.8,0.181,10,0.1,0.123,0,0,0,0.903,0,0,-0.8,2
ENSMUSG00000020638,CMPK2,"cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial",nucleus|mitochondrion|,nucleoside diphosphate phosphorylation|pyrimidine nucleotide biosynthetic process|dUDP biosynthetic process|dTDP biosynthetic process|nucleoside triphosphate biosynthetic process|phosphorylation|cellular response to lipopolysaccharide|,nucleotide binding|cytidylate kinase activity|nucleoside diphosphate kinase activity|thymidylate kinase activity|ATP binding|uridylate kinase activity|kinase activity|transferase activity|UMP kinase activity|,9,1.7,0.89,9,0,0,0,0,0,0.903,0,0,-0.8,3
ENSMUSG00000067010,VMN2R10,"vomeronasal 2, receptor 10",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.3,0.466,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000085584,RGAG1,retrotransposon gag domain containing 1,cellular_component|,biological_process|,molecular_function|,9,0.1,0.0562,9,0,0,0,0,0,0.903,0,0,-1.5,1.6
ENSMUSG00000022309,ANGPT1,angiopoietin 1,extracellular region|extracellular space|plasma membrane|microvillus|membrane raft|extracellular vesicular exosome|,angiogenesis|angiogenesis|ovarian follicle development|patterning of blood vessels|vasculogenesis|in utero embryonic development|in utero embryonic development|sprouting angiogenesis|positive regulation of receptor internalization|endocardium morphogenesis|negative regulation of cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|activation of transmembrane receptor protein tyrosine kinase activity|multicellular organismal development|endoderm development|positive regulation of endothelial cell migration|positive regulation of endothelial cell migration|positive regulation of phosphatidylinositol 3-kinase signaling|regulation of satellite cell proliferation|hemopoiesis|cell differentiation|heparin biosynthetic process|positive regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of protein ubiquitination|cell-substrate adhesion|positive regulation of peptidyl-serine phosphorylation|protein localization to cell surface|negative regulation of apoptotic process|negative regulation of vascular permeability|negative regulation of vascular permeability|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of blood vessel endothelial cell migration|positive regulation of cell adhesion|Tie signaling pathway|Tie signaling pathway|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|positive chemotaxis|protein homooligomerization|positive regulation of protein kinase B signaling|cardiac muscle tissue morphogenesis|vasculogenesis involved in coronary vascular morphogenesis|positive regulation of ERK1 and ERK2 cascade|glomerulus vasculature development|glomerulus vasculature development|negative regulation of endothelial cell apoptotic process|,receptor binding|vascular endothelial growth factor receptor binding|receptor tyrosine kinase binding|,10,0,0,10,0.7,0.579,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000020081,TACR2,tachykinin receptor 2,cell|plasma membrane|membrane|integral component of membrane|,"signal transduction|G-protein coupled receptor signaling pathway|tachykinin receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|positive regulation of acetylcholine secretion, neurotransmission|intestine smooth muscle contraction|negative regulation of luteinizing hormone secretion|operant conditioning|positive regulation of vascular permeability|positive regulation of ion transport|prolactin secretion|positive regulation of uterine smooth muscle contraction|",signal transducer activity|G-protein coupled receptor activity|tachykinin receptor activity|substance K receptor activity|,10,0,0,10,-0.1,0.00925,0,0,0,0.903,0,0,-1.8,1.3
ENSMUSG00000030852,TACC2,"transforming, acidic coiled-coil containing protein 2",nucleus|nucleolus|cytoplasm|Golgi apparatus|cytoskeleton|,microtubule cytoskeleton organization|cell proliferation|cerebral cortex development|neurogenesis|interkinetic nuclear migration|astral microtubule organization|regulation of microtubule-based process|,protein domain specific binding|nuclear hormone receptor binding|,10,-0.2,0.188,10,0,0,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000002265,PEG3,paternally expressed 3,nucleus|cytoplasm|,in utero embryonic development|apoptotic process|regulation of gene expression|multicellular organism growth|genetic imprinting|,nucleic acid binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000016758,BIK,BCL2-interacting killer,mitochondrion|mitochondrial envelope|membrane|integral component of membrane|,apoptotic process|spermatogenesis|male gonad development|apoptotic mitochondrial changes|positive regulation of protein homooligomerization|positive regulation of release of cytochrome c from mitochondria|,protein binding|protein heterodimerization activity|BH domain binding|,10,-0.1,0.0781,10,-1,0.581,0,0,0,0.903,0,0,-2,1
ENSMUSG00000055799,TCF7L1,"transcription factor 7 like 1 (T cell specific, HMG box)",nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|brain development|anterior/posterior axis specification, embryo|Wnt signaling pathway|somatic stem cell maintenance|skin development|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter during mitosis|axial mesoderm morphogenesis|generation of neurons|stem cell differentiation|canonical Wnt signaling pathway|regulation of stem cell maintenance|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|beta-catenin binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0,0,10,-1,1.77,0,0,0,0.903,0,0,-2,0.8
ENSMUSG00000002944,CD36,CD36 antigen,extracellular space|intracellular|mitochondrion|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|caveola|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|sarcolemma|intracellular membrane-bounded organelle|protein complex|membrane raft|apical part of cell|,"negative regulation of transcription from RNA polymerase II promoter|long-chain fatty acid metabolic process|positive regulation of cell-matrix adhesion|pattern recognition receptor signaling pathway|negative regulation of systemic arterial blood pressure|fatty acid metabolic process|triglyceride metabolic process|transport|receptor-mediated endocytosis|receptor-mediated endocytosis|phagocytosis, recognition|cell adhesion|signal transduction|cell surface receptor signaling pathway|nitric oxide mediated signal transduction|response to mechanical stimulus|negative regulation of gene expression|positive regulation of macrophage derived foam cell differentiation|positive regulation of macrophage derived foam cell differentiation|positive regulation of cholesterol storage|fatty acid transport|long-chain fatty acid transport|plasma membrane long-chain fatty acid transport|negative regulation of angiogenesis|fatty acid oxidation|lipid storage|lipid storage|cGMP-mediated signaling|positive regulation of blood coagulation|cholesterol transport|positive regulation of interleukin-12 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|plasma lipoprotein particle clearance|low-density lipoprotein particle clearance|low-density lipoprotein particle clearance|lipoprotein transport|lipoprotein transport|negative regulation of transcription factor import into nucleus|positive regulation of I-kappaB kinase/NF-kappaB signaling|apoptotic cell clearance|positive regulation of MAPK cascade|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|negative regulation of growth of symbiont in host|long-chain fatty acid import|positive regulation of cytokine secretion|positive regulation of peptidyl-tyrosine phosphorylation|defense response to Gram-positive bacterium|low-density lipoprotein particle mediated signaling|positive regulation of phagocytosis, engulfment|positive regulation of phagocytosis, engulfment|positive regulation of macrophage cytokine production|cellular response to bacterial lipopeptide|cellular response to lipopolysaccharide|cellular response to lipoteichoic acid|cellular response to lipoteichoic acid|cellular response to hydroperoxide|regulation of removal of superoxide radicals|positive regulation of blood microparticle formation|positive regulation of reactive oxygen species metabolic process|",low-density lipoprotein receptor activity|low-density lipoprotein receptor activity|protein binding|high-density lipoprotein particle binding|lipid binding|lipid binding|low-density lipoprotein particle binding|low-density lipoprotein particle binding|transforming growth factor beta binding|thrombospondin receptor activity|oleic acid binding|lipoteichoic acid receptor activity|lipoprotein particle binding|,10,-0.1,0.0576,10,0,0,0,0,0,0.903,0,0,-2,0.8
ENSMUSG00000021209,PPP4R4,"protein phosphatase 4, regulatory subunit 4",cytoplasm|protein serine/threonine phosphatase complex|,negative regulation of phosphoprotein phosphatase activity|regulation of protein serine/threonine phosphatase activity|,protein binding|protein phosphatase regulator activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.9,1.2
ENSMUSG00000040584,ABCB1A,"ATP-binding cassette, sub-family B (MDR/TAP), member 1A",plasma membrane|cell surface|membrane|integral component of membrane|apical part of cell|intercellular canaliculus|extracellular vesicular exosome|,G2/M transition of mitotic cell cycle|ATP catabolic process|transport|drug transmembrane transport|hormone transport|drug transport|daunorubicin transport|drug export|transmembrane transport|negative regulation of cell death|establishment of blood-brain barrier|stem cell proliferation|positive regulation of response to drug|,"nucleotide binding|ATP binding|xenobiotic-transporting ATPase activity|hydrolase activity|ATPase activity|ATPase activity, coupled|ATPase activity, coupled to transmembrane movement of substances|",10,0.3,0.058,10,0,0,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000001521,TULP3,tubby-like protein 3,extracellular region|nucleus|nucleolus|cytoplasm|plasma membrane|cilium|cilium|axoneme|membrane|intraciliary transport particle A|cell projection|primary cilium|primary cilium|ciliary base|,neural tube formation|neural tube closure|multicellular organismal development|brain development|regulation of G-protein coupled receptor protein signaling pathway|regulation of smoothened signaling pathway|anterior/posterior pattern specification|dorsal/ventral neural tube patterning|negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning|neural tube development|central nervous system neuron differentiation|embryonic camera-type eye development|embryonic digit morphogenesis|negative regulation of smoothened signaling pathway|negative regulation of smoothened signaling pathway|embryonic neurocranium morphogenesis|limb development|limb development|bone development|bronchus morphogenesis|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|ganglion development|negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|,enzyme binding|protein complex binding|phosphatidylinositol binding|,10,0.7,0.258,10,0,0,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000022018,RGCC,regulator of cell cycle,nucleus|cytoplasm|centrosome|cytoskeleton|,G1/S transition of mitotic cell cycle|negative regulation of exit from mitosis|negative regulation of endothelial cell proliferation|positive regulation of extracellular matrix constituent secretion|complement activation|cell cycle|negative regulation of cell proliferation|positive regulation of epithelial to mesenchymal transition|negative regulation of angiogenesis|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|positive regulation of collagen biosynthetic process|negative regulation of blood vessel endothelial cell migration|positive regulation of mitosis|negative regulation of cytokine secretion|positive regulation of cytokine secretion|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of stress fiber assembly|regulation of cell cycle|positive regulation of cell cycle arrest|cellular response to hypoxia|mitotic cell cycle arrest|fibroblast activation|negative regulation of fibroblast growth factor production|positive regulation of gene expression involved in extracellular matrix organization|negative regulation of mitotic cell cycle phase transition|negative regulation of cell-cell adhesion mediated by cadherin|positive regulation of endothelial cell apoptotic process|,protein binding|protein kinase binding|protein kinase activator activity|R-SMAD binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.6
ENSMUSG00000001173,OCRL,oculocerebrorenal syndrome of Lowe,photoreceptor outer segment|intracellular|nucleus|cytoplasm|endosome|early endosome|Golgi apparatus|trans-Golgi network|plasma membrane|coated pit|cilium|membrane|clathrin-coated vesicle|cytoplasmic vesicle|cell projection|extracellular vesicular exosome|,in utero embryonic development|signal transduction|cell projection organization|regulation of Rac GTPase activity|positive regulation of Rac GTPase activity|cilium assembly|phosphatidylinositol dephosphorylation|,"phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|hydrolase activity|Rac GTPase activator activity|Rac GTPase binding|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1.1,1.9
ENSMUSG00000029603,DTX1,deltex 1 homolog (Drosophila),nucleus|cytoplasm|,Notch signaling pathway|Notch signaling pathway|regulation of Notch signaling pathway|glial cell differentiation|negative regulation of T cell differentiation|negative regulation of neuron differentiation|,"Notch binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|SH3 domain binding|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.0825,10,-0.1,0.11,0,0,0,0.903,0,0,-1,2
ENSMUSG00000004562,ARHGEF40,Rho guanine nucleotide exchange factor (GEF) 40,cellular_component|cytoplasm|,biological_process|regulation of Rho protein signal transduction|,molecular_function|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0,0,10,0.1,0.159,0,0,0,0.903,0,0,-1.7,1.2
ENSMUSG00000020156,MUM1,melanoma associated antigen (mutated) 1,nucleus|,DNA repair|chromatin organization|cellular response to DNA damage stimulus|,nucleosome binding|,10,-0.2,0.567,10,0.1,0.0211,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000032098,TREH,trehalase (brush-border membrane glycoprotein),plasma membrane|brush border|membrane|anchored component of membrane|extracellular vesicular exosome|,trehalose metabolic process|metabolic process|organ morphogenesis|,"catalytic activity|alpha,alpha-trehalase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000027568,NTSR1,neurotensin receptor 1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|adult locomotory behavior|,signal transducer activity|G-protein coupled receptor activity|neuropeptide receptor activity|G-protein coupled neurotensin receptor activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000019301,HSD17B1,hydroxysteroid (17-beta) dehydrogenase 1,nucleus|cytoplasm|cytosol|nuclear membrane|,lipid metabolic process|steroid biosynthetic process|estrogen biosynthetic process|metabolic process|oxidation-reduction process|testosterone biosynthetic process|,estradiol 17-beta-dehydrogenase activity|oxidoreductase activity|testosterone dehydrogenase (NAD+) activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000054203,IFI205,interferon activated gene 205,nucleus|nucleolus|cytoplasm|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to interferon-beta|",double-stranded DNA binding|double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,10,0,0,10,0.7,2.21,0,0,0,0.903,0,0,-2,1.4
ENSMUSG00000024981,ACSL5,acyl-CoA synthetase long-chain family member 5,nucleus|nucleolus|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|endoplasmic reticulum|endoplasmic reticulum|membrane|membrane|integral component of membrane|,long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|metabolic process|phospholipid biosynthetic process|positive regulation of plasma membrane long-chain fatty acid transport|positive regulation of triglyceride biosynthetic process|fatty acid transport|positive regulation of fatty acid beta-oxidation|regulation of extrinsic apoptotic signaling pathway|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|ATP binding|ligase activity|,10,-0.1,0.203,10,0.2,0.689,0,0,0,0.903,0,0,-1.9,1.1
ENSMUSG00000024256,ADCYAP1,adenylate cyclase activating polypeptide 1,extracellular region|extracellular space|intracellular|terminal bouton|,"ovarian follicle development|behavioral fear response|histamine secretion|negative regulation of acute inflammatory response to antigenic stimulus|negative regulation of acute inflammatory response to non-antigenic stimulus|activation of adenylate cyclase activity|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|neuropeptide signaling pathway|nervous system development|regulation of G-protein coupled receptor protein signaling pathway|positive regulation of cell proliferation|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of gene expression|negative regulation of muscle cell apoptotic process|positive regulation of neuron projection development|sensory perception of pain|cAMP-mediated signaling|positive regulation of cAMP biosynthetic process|neuron projection development|positive regulation of interleukin-6 production|positive regulation of Rap GTPase activity|regulation of protein localization|regulation of protein localization|negative regulation of Rho GTPase activity|intracellular signal transduction|negative regulation of potassium ion transport|negative regulation of cell cycle|positive regulation of protein kinase activity|positive regulation of vasodilation|positive regulation of transcription from RNA polymerase II promoter|ATP metabolic process|positive regulation of synaptic transmission, glutamatergic|regulation of postsynaptic membrane potential|positive regulation of growth hormone secretion|negative regulation of glial cell proliferation|positive regulation of ERK1 and ERK2 cascade|regulation of oligodendrocyte progenitor proliferation|positive regulation of somatostatin secretion|",receptor signaling protein activity|receptor signaling protein activity|receptor binding|hormone activity|neuropeptide hormone activity|neuropeptide hormone activity|pituitary adenylate cyclase activating polypeptide activity|pituitary adenylate cyclase activating polypeptide activity|pituitary adenylate cyclase-activating polypeptide receptor binding|peptide hormone receptor binding|,10,-0.2,0.354,10,0,0,0,0,0,0.903,0,0,-1.8,1.1
ENSMUSG00000054051,ERCC6,"excision repair cross-complementing rodent repair deficiency, complementation group 6",intracellular|nucleus|nucleoplasm|nucleolus|transcription elongation factor complex|,"response to superoxide|ATP catabolic process|DNA repair|DNA repair|transcription-coupled nucleotide-excision repair|transcription-coupled nucleotide-excision repair|base-excision repair|pyrimidine dimer repair|transcription elongation from RNA polymerase I promoter|cellular response to DNA damage stimulus|response to oxidative stress|response to oxidative stress|activation of JNKK activity|activation of JUN kinase activity|intrinsic apoptotic signaling pathway in response to DNA damage|response to UV|response to UV|response to toxic substance|response to X-ray|response to UV-B|response to gamma radiation|regulation of DNA-templated transcription, elongation|positive regulation of DNA-templated transcription, elongation|multicellular organism growth|photoreceptor cell maintenance|",DNA binding|chromatin binding|ATP binding|protein C-terminus binding|DNA-dependent ATPase activity|protein tyrosine kinase activator activity|protein complex binding|protein N-terminus binding|,9,0.1,0.033,9,0,0,0,0,0,0.903,0,0,-1.5,1.6
ENSMUSG00000059280,VPREB2,pre-B lymphocyte gene 2,None,cell morphogenesis|regulation of cell size|B cell proliferation|homeostasis of number of cells|,None,10,0,0,10,-0.1,0.00873,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000044749,ABCA6,"ATP-binding cassette, sub-family A (ABC1), member 6",cellular_component|membrane|integral component of membrane|,transport|biological_process|,nucleotide binding|molecular_function|ATP binding|ATPase activity|,10,-0.8,0.249,10,-0.1,0.0284,0,0,0,0.903,0,0,-1.9,1.2
ENSMUSG00000023495,PCBP4,poly(rC) binding protein 4,cytoplasm|ribonucleoprotein complex|,None,DNA binding|RNA binding|poly(A) RNA binding|,10,0.1,0.0839,10,-0.3,1.04,0,0,0,0.903,0,0,-1.6,1.3
ENSMUSG00000038347,TCTE2,t-complex-associated testis expressed 2,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0677,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000021356,IRF4,interferon regulatory factor 4,nuclear nucleosome|nucleus|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein methylation|peptidyl-lysine methylation|negative regulation of toll-like receptor signaling pathway|defense response to protozoan|myeloid dendritic cell differentiation|positive regulation of DNA binding|histone H3 acetylation|histone H4 acetylation|positive regulation of interleukin-10 biosynthetic process|positive regulation of interleukin-2 biosynthetic process|positive regulation of interleukin-13 biosynthetic process|positive regulation of interleukin-4 biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|T-helper 17 cell lineage commitment|",regulatory region DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein-lysine N-methyltransferase activity|sequence-specific DNA binding|,10,0,0,10,0.1,0.00241,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000021340,GPLD1,glycosylphosphatidylinositol specific phospholipase D1,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|intracellular|cytoplasm|cytoplasm|lysosomal membrane|membrane|integral component of membrane|high-density lipoprotein particle|intracellular membrane-bounded organelle|intracellular membrane-bounded organelle|,cell migration involved in sprouting angiogenesis|complement receptor mediated signaling pathway|GPI anchor release|GPI anchor release|GPI anchor release|cell adhesion|integrin-mediated signaling pathway|negative regulation of cell proliferation|insulin receptor signaling pathway|response to glucose|positive regulation of endothelial cell migration|positive regulation of triglyceride biosynthetic process|negative regulation of triglyceride catabolic process|positive regulation of glucose metabolic process|positive regulation of high-density lipoprotein particle clearance|cellular response to insulin stimulus|cellular response to drug|positive regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of apoptotic process|positive regulation of cytolysis|positive regulation of membrane protein ectodomain proteolysis|positive regulation of membrane protein ectodomain proteolysis|positive regulation of secretion|transepithelial transport|cellular response to inorganic substance|cellular response to calcium ion|cellular response to iron(II) ion|cellular response to cholesterol|cellular response to triglyceride|cellular response to pH|regulation of cellular response to insulin stimulus|,glycosylphosphatidylinositol phospholipase D activity|glycosylphosphatidylinositol phospholipase D activity|phospholipase D activity|phospholipase D activity|protein binding|hydrolase activity|sodium channel regulator activity|,9,0.1,0.151,9,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000051596,OTOP1,otopetrin 1,extracellular region|membrane|integral component of membrane|,detection of gravity|biomineral tissue development|inner ear morphogenesis|,None,10,0.1,0.0212,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000079019,INSL3,insulin-like 3,extracellular region|extracellular space|perinuclear region of cytoplasm|,oocyte maturation|in utero embryonic development|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|positive regulation of cell proliferation|negative regulation of cell proliferation|male gonad development|male gonad development|positive regulation of cAMP biosynthetic process|negative regulation of apoptotic process|,G-protein coupled receptor binding|protease binding|hormone activity|,10,0,0,10,-0.1,0.0309,0,0,0,0.903,0,0,-1.3,1.8
ENSMUSG00000026394,ATP6V1G3,"ATPase, H+ transporting, lysosomal V1 subunit G3",cytosol|cytosol|plasma membrane|plasma membrane|membrane|vacuolar proton-transporting V-type ATPase complex|,ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|hydrogen ion transmembrane transport|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|ATPase binding|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000026109,TMEFF2,transmembrane protein with EGF-like and two follistatin-like domains 2,membrane|integral component of membrane|,None,None,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.8
ENSMUSG00000003872,LIN7B,lin-7 homolog B (C. elegans),cell|plasma membrane|cell-cell junction|tight junction|membrane|cell junction|neuron projection|synapse|postsynaptic membrane|,transport|exocytosis|neurotransmitter secretion|protein transport|,protein domain specific binding|,10,0.1,0.183,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000025969,NRP2,neuropilin 2,plasma membrane|membrane|integral component of membrane|axon|,angiogenesis|neural crest cell migration|neuron migration|cell adhesion|multicellular organismal development|nervous system development|axon guidance|heart development|nerve development|gonadotrophin-releasing hormone neuronal migration to the hypothalamus|cell differentiation|vascular endothelial growth factor signaling pathway|axon extension involved in axon guidance|negative chemotaxis|negative chemotaxis|sympathetic ganglion development|semaphorin-plexin signaling pathway|sympathetic neuron projection extension|sympathetic neuron projection guidance|semaphorin-plexin signaling pathway involved in neuron projection guidance|,vascular endothelial growth factor-activated receptor activity|protein binding|heparin binding|semaphorin receptor activity|metal ion binding|,10,0,0,10,-0.2,0.00577,0,0,0,0.903,0,0,-2,1
ENSMUSG00000074254,CYP2A4,"cytochrome P450, family 2, subfamily a, polypeptide 4",cytoplasmic microtubule|,oxidation-reduction process|,coumarin 7-hydroxylase activity|enzyme binding|heme binding|,10,-0.7,0.566,10,0.1,0.1,0,0,0,0.903,0,0,-1.9,1.1
ENSMUSG00000021214,AKR1C18,"aldo-keto reductase family 1, member C18",intracellular|nucleus|cytoplasm|cytosol|extracellular vesicular exosome|,"protein import into nucleus, translocation|progesterone catabolic process|progesterone catabolic process|G-protein coupled receptor signaling pathway|parturition|positive regulation of cell proliferation|positive regulation of cell death|farnesol catabolic process|cellular response to reactive oxygen species|response to prostaglandin|progesterone metabolic process|retinal metabolic process|daunorubicin metabolic process|doxorubicin metabolic process|regulation of retinoic acid receptor signaling pathway|regulation of steroid biosynthetic process|positive regulation of protein kinase B signaling|oxidation-reduction process|oxidation-reduction process|testosterone biosynthetic process|cellular response to cadmium ion|cellular response to calcium ion|cellular response to prostaglandin stimulus|cellular response to corticosteroid stimulus|cellular response to jasmonic acid stimulus|negative regulation of retinoic acid biosynthetic process|regulation of testosterone biosynthetic process|positive regulation of endothelial cell apoptotic process|positive regulation of reactive oxygen species metabolic process|","retinal dehydrogenase activity|alditol:NADP+ 1-oxidoreductase activity|retinol dehydrogenase activity|prostaglandin F receptor activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|phenanthrene 9,10-monooxygenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|versicolorin reductase activity|geranylgeranyl reductase activity|ketoreductase activity|17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity|17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity|17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity|15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity|androsterone dehydrogenase activity|ketosteroid monooxygenase activity|delta4-3-oxosteroid 5beta-reductase activity|",10,0,0,10,-0.1,0.106,0,0,0,0.903,0,0,-1.6,1.5
ENSMUSG00000061808,TTR,transthyretin,extracellular region|extracellular space|protein complex|extracellular vesicular exosome|,transport|retinol metabolic process|,hormone activity|protein binding|hormone binding|identical protein binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000017300,TNNC2,"troponin C2, fast",troponin complex|,skeletal muscle contraction|,actin binding|calcium ion binding|metal ion binding|,10,0,0,10,0.2,0.356,0,0,0,0.903,0,0,-1.3,1.6
ENSMUSG00000029086,PROM1,prominin 1,photoreceptor outer segment|extracellular space|extracellular space|plasma membrane|integral component of plasma membrane|microvillus|brush border|cilium|cell surface|cell surface|membrane|integral component of membrane|apical plasma membrane|stereocilium|photoreceptor outer segment membrane|cell projection|extracellular vesicular exosome|prominosome|,retina layer formation|photoreceptor cell maintenance|retina morphogenesis in camera-type eye|camera-type eye photoreceptor cell differentiation|camera-type eye photoreceptor cell differentiation|glomerular visceral epithelial cell differentiation|glomerular parietal epithelial cell differentiation|positive regulation of nephron tubule epithelial cell differentiation|,actinin binding|cadherin binding|,9,0,0,9,-0.1,0.0618,0,0,0,0.903,0,0,-1.6,1.5
ENSMUSG00000016458,WT1,Wilms tumor 1 homolog,nucleus|nucleus|nucleoplasm|cytoplasm|cytoplasm|nuclear speck|nuclear speck|,"negative regulation of transcription from RNA polymerase II promoter|vasculogenesis|metanephros development|ureteric bud development|branching involved in ureteric bud morphogenesis|branching involved in ureteric bud morphogenesis|kidney development|kidney development|mesonephros development|regulation of organ formation|apoptotic DNA fragmentation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|germ cell development|thorax and anterior abdomen determination|heart development|heart development|sex determination|sex determination|negative regulation of cell proliferation|RNA splicing|gonad development|male gonad development|male gonad development|tissue development|negative regulation of translation|negative regulation of cell growth|adrenal gland development|adrenal gland development|male genitalia development|epithelial cell differentiation|glomerulus development|glomerulus development|glomerular basement membrane development|adrenal cortex formation|camera-type eye development|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|mesenchymal to epithelial transition|positive regulation of heart growth|diaphragm development|cardiac muscle cell fate commitment|coronary vasculature development|visceral serous pericardium development|visceral serous pericardium development|visceral serous pericardium development|cellular response to cAMP|cellular response to gonadotropin stimulus|cellular response to gonadotropin stimulus|metanephric mesenchyme development|glomerular visceral epithelial cell differentiation|posterior mesonephric tubule development|metanephric S-shaped body morphogenesis|metanephric S-shaped body morphogenesis|negative regulation of metanephric glomerular mesangial cell proliferation|negative regulation of mesenchymal cell apoptotic process involved in metanephros development|positive regulation of male gonad development|negative regulation of female gonad development|positive regulation of metanephric ureteric bud development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|RNA binding|protein binding|zinc ion binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|C2H2 zinc finger domain binding|C2H2 zinc finger domain binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000029781,FKBP9,FK506 binding protein 9,endoplasmic reticulum|endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|calcium ion binding|FK506 binding|isomerase activity|metal ion binding|,10,0.1,0.0645,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000027663,ZMAT3,zinc finger matrin type 3,nucleus|nucleolus|,transport|apoptotic process|cellular response to DNA damage stimulus|protein transport|negative regulation of cell growth|regulation of growth|positive regulation of apoptotic process|,nucleic acid binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,-0.1,0.0119,0,0,0,0.903,0,0,-1.6,1.5
ENSMUSG00000031104,RAB33A,"RAB33A, member RAS oncogene family",plasma membrane|membrane|,small GTPase mediated signal transduction|protein transport|antigen processing and presentation|,nucleotide binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000074928,KRTAP14,keratin associated protein 14,intermediate filament|,None,None,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000030189,YBX3,Y box protein 3,nucleus|nucleus|cytoplasm|cytoplasm|polysome|gap junction|ribonucleoprotein complex|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|male gonad development|fertilization|negative regulation of apoptotic process|positive regulation of organ growth|negative regulation of skeletal muscle tissue development|negative regulation of necroptotic process|cellular response to tumor necrosis factor|cellular hyperosmotic response|negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|",nucleic acid binding|DNA binding|single-stranded DNA binding|single-stranded DNA binding|RNA binding|mRNA 3'-UTR binding|protein binding|poly(A) RNA binding|,10,0.1,0.0461,10,-0.4,0.335,0,0,0,0.903,0,0,-1.9,1
ENSMUSG00000070390,NLRP1B,"NLR family, pyrin domain containing 1B",nucleus|NLRP1 inflammasome complex|,activation of cysteine-type endopeptidase activity involved in apoptotic process|protein catabolic process|interleukin-1 alpha production|interleukin-1 beta production|interleukin-1 beta production|neuron apoptotic process|pyroptosis|,nucleotide binding|ATP binding|enzyme binding|protein domain specific binding|,10,-0.8,0.0541,10,0,0,0,0,0,0.903,0,0,-2,0.7
ENSMUSG00000022435,UPK3A,uroplakin 3A,endoplasmic reticulum|membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,cell morphogenesis|kidney development|water transport|urea transport|epithelial cell differentiation|potassium ion homeostasis|sodium ion homeostasis|urinary bladder development|,None,10,0,0,10,0,0,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000001131,TIMP1,tissue inhibitor of metalloproteinase 1,extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|extracellular matrix|extracellular vesicular exosome|,cell activation|positive regulation of cell proliferation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of apoptotic process|negative regulation of metalloenzyme activity|negative regulation of membrane protein ectodomain proteolysis|negative regulation of trophoblast cell migration|regulation of integrin-mediated signaling pathway|,protease binding|enzyme inhibitor activity|cytokine activity|growth factor activity|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|metal ion binding|,10,-0.3,0.362,10,0,0,0,0,0,0.903,0,0,-1.9,1.1
ENSMUSG00000021270,HSP90AA1,"heat shock protein 90, alpha (cytosolic), class A member 1",intracellular|nucleus|cytoplasm|cytoplasm|mitochondrion|cytosol|cytosol|plasma membrane|cell surface|membrane|membrane|basolateral plasma membrane|apical plasma membrane|extracellular matrix|brush border membrane|neuron projection|neuronal cell body|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,"neuron migration|ATP catabolic process|protein folding|nitric oxide biosynthetic process|response to stress|response to unfolded protein|positive regulation of lamellipodium assembly|positive regulation of protein import into nucleus, translocation|protein refolding|protein import into mitochondrial outer membrane|positive regulation of nitric oxide biosynthetic process|positive regulation of cytotoxic T cell differentiation|positive regulation of cell size|regulation of catalytic activity|chaperone-mediated protein complex assembly|",nucleotide binding|UTP binding|CTP binding|mRNA binding|protein binding|ATP binding|GTP binding|ATPase activity|sulfonylurea receptor binding|protein kinase binding|protein phosphatase binding|MHC class II protein complex binding|nitric-oxide synthase regulator activity|nitric-oxide synthase regulator activity|TPR domain binding|dATP binding|identical protein binding|protein homodimerization activity|ion channel binding|poly(A) RNA binding|unfolded protein binding|,10,-0.7,0.103,10,-0.1,0.174,0,0,0,0.903,0,0,-2,0.7
ENSMUSG00000014748,TEX261,testis expressed gene 261,cellular_component|membrane|integral component of membrane|,positive regulation of apoptotic process|,molecular_function|,10,0,0,10,0.6,1.57,0,0,0,0.903,0,0,-2,1.2
ENSMUSG00000033585,NDN,necdin,nucleus|cytoplasm|cytoplasm|centrosome|cytosol|cell projection|,"regulation of cell growth|neuron migration|respiratory system process|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular calcium ion homeostasis|axonogenesis|axonal fasciculation|central nervous system development|respiratory gaseous exchange|glial cell migration|post-embryonic development|sensory perception of pain|regulation of growth|neurotrophin TRK receptor signaling pathway|neuron development|axon extension|multicellular organismal homeostasis|genetic imprinting|",DNA binding|protein binding|gamma-tubulin binding|,10,0,0,10,0.1,0.0118,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000020673,TPO,thyroid peroxidase,extracellular space|mitochondrion|plasma membrane|cell surface|membrane|integral component of membrane|,response to oxidative stress|embryonic hemopoiesis|hormone biosynthetic process|hydrogen peroxide catabolic process|oxidation-reduction process|,iodide peroxidase activity|peroxidase activity|calcium ion binding|oxidoreductase activity|heme binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000015947,FCGR1,"Fc receptor, IgG, high affinity I",plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,"antibody-dependent cellular cytotoxicity|positive regulation of type IIa hypersensitivity|positive regulation of type III hypersensitivity|immune system process|receptor-mediated endocytosis|phagocytosis, recognition|phagocytosis, engulfment|cell surface receptor signaling pathway|response to bacterium|antigen processing and presentation of exogenous antigen|Fc-gamma receptor signaling pathway|antigen processing and presentation of exogenous peptide antigen via MHC class I|defense response to bacterium|innate immune response|positive regulation of phagocytosis|regulation of immune response|",IgG receptor activity|IgG binding|IgG binding|,10,-0.9,0.627,10,0.2,0.139,0,0,0,0.903,0,0,-2,1
ENSMUSG00000038058,NOD1,nucleotide-binding oligomerization domain containing 1,cytoplasm|plasma membrane|membrane|basolateral plasma membrane|,immune system process|positive regulation of dendritic cell antigen processing and presentation|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|defense response|detection of bacterium|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of stress-activated MAPK cascade|intracellular signal transduction|interleukin-8 biosynthetic process|defense response to bacterium|regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|innate immune response|positive regulation of JNK cascade|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|positive regulation of NF-kappaB transcription factor activity|positive regulation of ERK1 and ERK2 cascade|,nucleotide binding|protein binding|ATP binding|identical protein binding|protein homodimerization activity|CARD domain binding|,10,0.1,0.354,10,0,0,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000000303,CDH1,cadherin 1,cytoplasm|cytoplasm|endosome|Golgi apparatus|trans-Golgi network|plasma membrane|plasma membrane|cell-cell junction|cell-cell junction|adherens junction|cell-cell adherens junction|cell-cell adherens junction|focal adhesion|cytoplasmic side of plasma membrane|cell surface|actin cytoskeleton|membrane|integral component of membrane|aggresome|basolateral plasma membrane|lateral plasma membrane|catenin complex|catenin complex|cell junction|axon|node of Ranvier|lateral loop|Schmidt-Lanterman incisure|apical junction complex|apical junction complex|axon terminus|apical part of cell|perinuclear region of cytoplasm|extracellular vesicular exosome|cell periphery|,"in utero embryonic development|trophectodermal cell differentiation|epithelial cell morphogenesis|cell adhesion|homophilic cell adhesion|synapse assembly|sensory perception of sound|single organismal cell-cell adhesion|single organismal cell-cell adhesion|calcium-dependent cell-cell adhesion|protein metabolic process|negative regulation of cell-cell adhesion|regulation of protein localization|regulation of water loss via skin|positive regulation of transcription factor import into nucleus|regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of transcription, DNA-templated|negative regulation of epithelial cell proliferation|protein homooligomerization|intestinal epithelial cell development|salivary gland cavitation|regulation of branching involved in salivary gland morphogenesis|tight junction assembly|cellular response to amino acid stimulus|cellular response to lithium ion|cellular response to indole-3-methanol|protein localization to plasma membrane|establishment of protein localization to plasma membrane|establishment of protein localization to plasma membrane|negative regulation of canonical Wnt signaling pathway|cochlea development|regulation of protein localization to cell surface|regulation of neuron migration|",glycoprotein binding|calcium ion binding|protein binding|beta-catenin binding|beta-catenin binding|protein phosphatase binding|protein domain specific binding|ankyrin binding|GTPase activating protein binding|gamma-catenin binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000073077,GM7173,predicted gene 7173,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.1,1.9
ENSMUSG00000039830,OLIG2,oligodendrocyte transcription factor 2,nucleus|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|spinal cord motor neuron differentiation|spinal cord oligodendrocyte cell differentiation|spinal cord oligodendrocyte cell fate specification|thalamus development|myelination|negative regulation of neuron differentiation|neuron fate commitment|oligodendrocyte differentiation|positive regulation of oligodendrocyte differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|protein dimerization activity|HMG box domain binding|,10,0,0,10,-0.1,0.0383,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000045064,ZC2HC1C,"zinc finger, C2HC-type containing 1C",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,-0.1,0.122,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000032839,TRPC1,"transient receptor potential cation channel, subfamily C, member 1",cytoplasm|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|sarcomere|costamere|protein complex|receptor complex|membrane raft|,transport|ion transport|cation transport|calcium ion transport|ion transmembrane transport|saliva secretion|positive regulation of release of sequestered calcium ion into cytosol|cytosolic calcium ion homeostasis|response to calcium ion|transmembrane transport|calcium ion transmembrane transport|,"ion channel activity|cation channel activity|calcium channel activity|protein binding|store-operated calcium channel activity|ion channel binding|inositol 1,4,5 trisphosphate binding|",10,0.1,0.239,10,-0.2,0.919,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000046160,OLIG1,oligodendrocyte transcription factor 1,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|neuron fate commitment|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein dimerization activity|,10,0.4,1.24,10,0,0,0,0,0,0.903,0,0,-0.9,1.9
ENSMUSG00000032292,NR2E3,"nuclear receptor subfamily 2, group E, member 3",nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cell proliferation|eye photoreceptor cell development|steroid hormone mediated signaling pathway|positive regulation of rhodopsin gene expression|positive regulation of transcription from RNA polymerase II promoter|retina development in camera-type eye|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000070501,BC094916,cDNA sequence BC094916,nucleus|nucleolus|cytoplasm|membrane|,biological_process|,double-stranded DNA binding|transcription factor binding|poly(A) RNA binding|,8,0,0,8,-0.2,0.331,0,0,0,0.903,0,0,-1.8,1.3
ENSMUSG00000041653,PNPLA3,patatin-like phospholipase domain containing 3,membrane|integral component of membrane|,lipid metabolic process|metabolic process|lipid catabolic process|triglyceride biosynthetic process|triglyceride catabolic process|,"dihydrolipoamide branched chain acyltransferase activity|phospholipase A2 activity|sterol O-acyltransferase activity|triglyceride lipase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|hydrolase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|mono-olein transacylation activity|diolein transacylation activity|peptidyl-lysine N-acetyltransferase activity|",10,0,0,10,0.2,0.103,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000042751,NMNAT2,nicotinamide nucleotide adenylyltransferase 2,cytoplasm|late endosome|Golgi apparatus|Golgi apparatus|trans-Golgi network|synapse|,biosynthetic process|NAD biosynthetic process|pyridine nucleotide biosynthetic process|,nucleotide binding|nicotinamide-nucleotide adenylyltransferase activity|catalytic activity|nicotinate-nucleotide adenylyltransferase activity|ATP binding|transferase activity|nucleotidyltransferase activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000028356,AMBP,alpha 1 microglobulin/bikunin,extracellular region|extracellular space|plasma membrane|cell surface|intracellular membrane-bounded organelle|extracellular vesicular exosome|blood microparticle|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|protein-chromophore linkage|protein catabolic process|protein maturation|,serine-type endopeptidase inhibitor activity|IgA binding|heme binding|peptidase inhibitor activity|small molecule binding|protein homodimerization activity|,10,0,0,10,-0.1,0.152,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000055547,APOBEC4,"apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)",cellular_component|,mRNA processing|biological_process|,"molecular_function|GTP cyclohydrolase activity|tRNA-specific adenosine deaminase activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines|N-cyclopropylmelamine deaminase activity|N-cyclopropylammeline deaminase activity|N-cyclopropylammelide alkylamino hydrolase activity|2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity|tRNA-specific adenosine-37 deaminase activity|archaeal-specific GTP cyclohydrolase activity|metal ion binding|tRNA-specific adenosine-34 deaminase activity|",10,0.2,0.253,10,-0.1,0.404,0,0,0,0.903,0,0,-1.3,1.6
ENSMUSG00000036856,WNT4,"wingless-type MMTV integration site family, member 4",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|extracellular space|cytoplasm|Golgi apparatus|cell surface|extracellular matrix|,"metanephros development|metanephros development|branching involved in ureteric bud morphogenesis|mesonephros development|embryonic epithelial tube formation|androgen biosynthetic process|signal transduction|cell-cell signaling|multicellular organismal development|gamete generation|sex differentiation|male gonad development|male gonad development|male gonad development|female gonad development|cellular response to starvation|negative regulation of gene expression|negative regulation of gene expression|negative regulation of steroid biosynthetic process|Wnt signaling pathway|protein palmitoylation|regulation of cell-cell adhesion|cell differentiation|neuron differentiation|female sex determination|female sex determination|negative regulation of cell migration|positive regulation of bone mineralization|positive regulation of Rho GTPase activity|positive regulation of aldosterone biosynthetic process|positive regulation of collagen biosynthetic process|T cell differentiation in thymus|immature T cell proliferation in thymus|tube morphogenesis|non-canonical Wnt signaling pathway|non-canonical Wnt signaling pathway via MAPK cascade|negative regulation of fibroblast growth factor receptor signaling pathway|hormone metabolic process|cell fate commitment|negative regulation of cell differentiation|positive regulation of osteoblast differentiation|positive regulation of meiosis|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|oocyte development|oocyte development|branching morphogenesis of an epithelial tube|anatomical structure development|smooth muscle cell differentiation|smooth muscle cell differentiation|positive regulation of stress fiber assembly|positive regulation of focal adhesion assembly|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|somatotropin secreting cell differentiation|thyroid-stimulating hormone-secreting cell differentiation|mesenchymal to epithelial transition|tertiary branching involved in mammary gland duct morphogenesis|kidney morphogenesis|negative regulation of wound healing|positive regulation of dermatome development|positive regulation of dermatome development|paramesonephric duct development|paramesonephric duct development|negative regulation of testicular blood vessel morphogenesis|renal vesicle formation|renal vesicle induction|metanephric mesenchymal cell differentiation|mesonephric tubule development|metanephric tubule formation|metanephric nephron development|metanephric nephron morphogenesis|establishment of protein localization to plasma membrane|establishment of protein localization to plasma membrane|negative regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|negative regulation of male gonad development|positive regulation of cortisol biosynthetic process|negative regulation of testosterone biosynthetic process|negative regulation of testosterone biosynthetic process|negative regulation of apoptotic signaling pathway|",transcription corepressor activity|receptor binding|frizzled binding|protein binding|,10,0,0,10,0.2,0.131,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000043518,RAI2,retinoic acid induced 2,cellular_component|,biological_process|,molecular_function|,9,0,0,9,0.1,0.073,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000010760,PHLDA2,"pleckstrin homology-like domain, family A, member 2",cytoplasm|membrane|,placenta development|organ morphogenesis|regulation of gene expression|regulation of cell migration|regulation of embryonic development|regulation of glycogen metabolic process|,None,10,0,0,10,-0.2,0.232,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000019066,RAB3D,"RAB3D, member RAS oncogene family",mitochondrion|plasma membrane|membrane|transport vesicle|zymogen granule|extracellular vesicular exosome|,transport|exocytosis|small GTPase mediated signal transduction|protein transport|regulation of exocytosis|peptidyl-cysteine methylation|,nucleotide binding|protein binding|GTP binding|GTPase binding|,10,-0.1,0.213,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000057455,RIT2,Ras-like without CAAX 2,nucleus|plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|,nucleotide binding|protein binding|calmodulin binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000053199,ARHGAP20,Rho GTPase activating protein 20,intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.8,1.3
ENSMUSG00000032849,ABCC4,"ATP-binding cassette, sub-family C (CFTR/MRP), member 4",plasma membrane|membrane|basolateral plasma membrane|platelet dense granule membrane|,drug transmembrane transport|positive regulation of smooth muscle cell proliferation|,nucleotide binding|ATP binding|drug transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000025888,CASP1,caspase 1,extracellular region|nucleus|cytoplasm|cytoplasm|mitochondrion|neuron projection|protein complex|IPAF inflammasome complex|NLRP1 inflammasome complex|NLRP3 inflammasome complex|NLRP3 inflammasome complex|AIM2 inflammasome complex|AIM2 inflammasome complex|,"response to hypoxia|response to hypoxia|microglial cell activation|proteolysis|proteolysis|apoptotic process|myoblast fusion|memory|response to organic cyclic compound|protein processing|protein processing|response to lipopolysaccharide|response to lipopolysaccharide|interleukin-1 beta production|response to ATP|response to drug|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of circadian sleep/wake cycle, non-REM sleep|positive regulation of cytokine secretion|positive regulation of cytokine secretion|positive regulation of interleukin-1 alpha secretion|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|regulation of inflammatory response|mitochondrial depolarization|membrane hyperpolarization|pyroptosis|cellular response to organic substance|execution phase of apoptosis|programmed necrotic cell death|",endopeptidase activity|cysteine-type endopeptidase activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|scaffold protein binding|,10,0,0,10,0.2,0.198,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000040785,TTC3,tetratricopeptide repeat domain 3,nucleus|mitochondrion|vacuole|,ubiquitin-dependent protein catabolic process|negative regulation of cell morphogenesis involved in differentiation|negative regulation of neuron differentiation|protein K48-linked ubiquitination|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.128,10,0,0,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000061723,TNNT3,"troponin T3, skeletal, fast",troponin complex|,skeletal muscle contraction|ATP catabolic process|regulation of muscle contraction|regulation of striated muscle contraction|regulation of ATPase activity|,actin binding|tropomyosin binding|tropomyosin binding|troponin C binding|calcium-dependent ATPase activity|troponin I binding|calcium-dependent protein binding|,10,0,0,10,0.3,0.463,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000018486,WNT9B,"wingless-type MMTV integration site family, member 9B",extracellular region|proteinaceous extracellular matrix|extracellular space|,"branching involved in ureteric bud morphogenesis|branching involved in ureteric bud morphogenesis|in utero embryonic development|kidney development|regulation of protein phosphorylation|regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|signal transduction|cell-cell signaling|multicellular organismal development|cellular response to starvation|regulation of asymmetric cell division|organ morphogenesis|Wnt signaling pathway|neuron differentiation|male genitalia development|regulation of tube size|positive regulation of catalytic activity|cell fate commitment|embryonic cranial skeleton morphogenesis|branching morphogenesis of an epithelial tube|palate development|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|kidney morphogenesis|uterus morphogenesis|kidney rudiment formation|mesenchymal stem cell maintenance involved in nephron morphogenesis|collecting duct development|establishment of planar polarity involved in nephron morphogenesis|nephron tubule morphogenesis|mesonephric tubule development|mesonephric tubule development|metanephric tubule development|metanephric tubule formation|mesonephric duct formation|",receptor binding|frizzled binding|,10,-0.4,0.422,10,0.1,0.0796,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000014725,ADAM28,a disintegrin and metallopeptidase domain 28,plasma membrane|membrane|integral component of membrane|,proteolysis|integrin-mediated signaling pathway|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.2,0.31,10,-0.1,0.195,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000020894,VAMP2,vesicle-associated membrane protein 2,intracellular|cell|trans-Golgi network|plasma membrane|plasma membrane|synaptic vesicle|synaptic vesicle|membrane|integral component of membrane|cell junction|clathrin-coated vesicle|secretory granule|secretory granule|synaptic vesicle membrane|SNARE complex|cytoplasmic vesicle|zymogen granule membrane|neuron projection|intracellular organelle|intracellular membrane-bounded organelle|neuron projection terminus|synapse|perinuclear region of cytoplasm|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex|synaptobrevin 2-SNAP-25-syntaxin-1a complex|synaptobrevin 2-SNAP-25-syntaxin-1a complex|extracellular vesicular exosome|,protein complex assembly|response to glucose|protein transport|synaptic vesicle exocytosis|vesicle-mediated transport|calcium ion-dependent exocytosis|calcium ion-dependent exocytosis|regulation of exocytosis|regulation of exocytosis|cellular response to insulin stimulus|Golgi to plasma membrane protein transport|long-term synaptic potentiation|regulation of vesicle-mediated transport|membrane fusion|positive regulation of intracellular protein transport|,SNARE binding|SNARE binding|protein binding|calmodulin binding|phospholipid binding|protein C-terminus binding|myosin binding|syntaxin-1 binding|syntaxin binding|protein complex binding|identical protein binding|,10,-0.1,0.329,10,0,0,0,0,0,0.903,0,0,-1.7,1.4
ENSMUSG00000026922,AGPAT2,"1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)",endoplasmic reticulum|membrane|integral component of membrane|,positive regulation of cytokine production|lipid metabolic process|phosphatidic acid biosynthetic process|metabolic process|phospholipid biosynthetic process|,"1-acylglycerol-3-phosphate O-acyltransferase activity|1-acylglycerol-3-phosphate O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.1,0.215,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000079105,C7,complement component 7,extracellular vesicular exosome|,cellular sodium ion homeostasis|,None,9,0,0,9,0,0,0,0,0,0.903,0,0,-1.5,1.7
ENSMUSG00000033170,CARD10,"caspase recruitment domain family, member 10",None,activation of NF-kappaB-inducing kinase activity|activation of NF-kappaB-inducing kinase activity|regulation of apoptotic process|,None,10,0,0,10,0.1,0.0317,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000042632,PLA2G6,"phospholipase A2, group VI",cytoplasm|mitochondrion|cytosol|membrane|,"positive regulation of protein phosphorylation|lipid metabolic process|chemotaxis|positive regulation of cytosolic calcium ion concentration|memory|metabolic process|urinary bladder smooth muscle contraction|lipid catabolic process|cardiolipin biosynthetic process|response to endoplasmic reticulum stress|positive regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of vasodilation|positive regulation of exocytosis|negative regulation of synaptic transmission, glutamatergic|positive regulation of protein kinase C signaling|positive regulation of release of cytochrome c from mitochondria|positive regulation of arachidonic acid secretion|regulation of store-operated calcium channel activity|positive regulation of ceramide biosynthetic process|",phospholipase A2 activity|calmodulin binding|hydrolase activity|ATP-dependent protein binding|calcium-independent phospholipase A2 activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.8
ENSMUSG00000030346,RAD51AP1,RAD51 associated protein 1,nucleus|,DNA repair|DNA recombination|cellular response to DNA damage stimulus|regulation of double-strand break repair via homologous recombination|cellular response to ionizing radiation|,DNA binding|double-stranded DNA binding|single-stranded DNA binding|RNA binding|,10,0.1,0.165,10,-0.1,0.0947,0,0,0,0.903,0,0,-2,1
ENSMUSG00000020427,IGFBP3,insulin-like growth factor binding protein 3,extracellular region|extracellular space|extracellular space|nucleus|insulin-like growth factor ternary complex|insulin-like growth factor binary complex|extracellular vesicular exosome|,regulation of cell growth|negative regulation of protein phosphorylation|protein phosphorylation|negative regulation of cell proliferation|regulation of glucose metabolic process|negative regulation of smooth muscle cell migration|regulation of growth|positive regulation of apoptotic process|positive regulation of catalytic activity|positive regulation of MAPK cascade|positive regulation of insulin-like growth factor receptor signaling pathway|type B pancreatic cell proliferation|positive regulation of myoblast differentiation|negative regulation of smooth muscle cell proliferation|,fibronectin binding|insulin-like growth factor binding|protein tyrosine phosphatase activator activity|growth factor binding|insulin-like growth factor I binding|insulin-like growth factor II binding|,10,-0.2,0.289,10,0,0,0,0,0,0.903,0,0,-1.7,1.4
ENSMUSG00000025519,TKTL2,transketolase-like 2,cytoplasm|,metabolic process|,catalytic activity|transketolase activity|transferase activity|metal ion binding|,10,0,0,10,0.8,1.45,0,0,0,0.903,0,0,-1.2,2
ENSMUSG00000021508,CXCL14,chemokine (C-X-C motif) ligand 14,extracellular region|extracellular space|Golgi apparatus|,immune response|inner ear development|,cytokine activity|chemokine activity|,10,-0.1,0.0818,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000010797,WNT2,"wingless-type MMTV integration site family, member 2",extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|plasma membrane|extracellular matrix|,positive regulation of endothelial cell proliferation|positive regulation of mesenchymal cell proliferation|cell-cell signaling|multicellular organismal development|positive regulation of cell proliferation|Wnt signaling pathway|Wnt signaling pathway|neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fibroblast proliferation|positive regulation of sequence-specific DNA binding transcription factor activity|atrial cardiac muscle tissue morphogenesis|positive regulation of cardiac muscle cell proliferation|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|cardiac epithelial to mesenchymal transition|lung induction|positive regulation of epithelial cell proliferation involved in lung morphogenesis|labyrinthine layer blood vessel development|positive regulation of canonical Wnt signaling pathway|,receptor binding|frizzled binding|frizzled binding|cytokine activity|,10,1,0.617,10,0,0,0,0,0,0.903,0,0,-0.6,2
ENSMUSG00000028572,HOOK1,hook homolog 1 (Drosophila),cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|HOPS complex|FHF complex|,transport|endosome organization|lysosome organization|multicellular organismal development|spermatogenesis|spermatid development|endosome to lysosome transport|protein transport|cell differentiation|early endosome to late endosome transport|,actin binding|protein binding|microtubule binding|microtubule binding|identical protein binding|,10,0,0,10,-0.3,0.242,0,0,0,0.903,0,0,-1.7,1.4
ENSMUSG00000042903,FOXO4,forkhead box O4,nucleus|cytoplasm|cytosol|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|cell cycle arrest|mitotic G2 DNA damage checkpoint|multicellular organismal development|muscle organ development|negative regulation of cell proliferation|negative regulation of cell proliferation|insulin receptor signaling pathway|negative regulation of angiogenesis|cell differentiation|positive regulation of transcription, DNA-templated|stem cell differentiation|negative regulation of smooth muscle cell differentiation|negative regulation of G0 to G1 transition|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|enzyme binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,-0.1,0.0237,10,0.2,0.453,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000009900,WNT3A,"wingless-type MMTV integration site family, member 3A",extracellular region|proteinaceous extracellular matrix|extracellular space|cell surface|,"osteoblast differentiation|in utero embryonic development|somitogenesis|positive regulation of protein phosphorylation|heart looping|positive regulation of receptor internalization|negative regulation of heart induction by canonical Wnt signaling pathway|signal transduction|cell-cell signaling|multicellular organismal development|determination of left/right symmetry|axonogenesis|axonogenesis|axon guidance|mesoderm development|positive regulation of cell proliferation|organ morphogenesis|anterior/posterior pattern specification|COP9 signalosome assembly|negative regulation of neuron projection development|Wnt signaling pathway|spinal cord association neuron differentiation|spinal cord association neuron differentiation|hippocampus development|cell proliferation in forebrain|Wnt signaling pathway involved in forebrain neuroblast division|dorsal/ventral neural tube patterning|hemopoiesis|platelet activation|extracellular matrix organization|BMP signaling pathway|mammary gland development|positive regulation of B cell proliferation|positive regulation of protein binding|positive regulation of peptidyl-serine phosphorylation|cellular protein localization|positive regulation of catenin import into nucleus|skeletal muscle cell differentiation|post-anal tail morphogenesis|inner ear morphogenesis|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of cell differentiation|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|somatic stem cell division|positive regulation of mesodermal cell fate specification|paraxial mesodermal cell fate commitment|positive regulation of collateral sprouting in absence of injury|negative regulation of axon extension involved in axon guidance|negative regulation of neurogenesis|regulation of axonogenesis|positive regulation of sequence-specific DNA binding transcription factor activity|palate development|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|cardiac muscle cell fate commitment|positive regulation of protein tyrosine kinase activity|positive regulation of dermatome development|canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment|regulation of microtubule cytoskeleton organization|platelet aggregation|axis elongation involved in somitogenesis|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|positive regulation of cell-cell adhesion mediated by cadherin|positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of receptor activity|positive regulation of cardiac muscle cell differentiation|",transcription coactivator activity|receptor binding|frizzled binding|frizzled-2 binding|protein binding|protein domain specific binding|receptor agonist activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000028736,PAX7,paired box 7,nucleus|transcription factor complex|,"chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|muscle organ development|skeletal muscle tissue development|organ morphogenesis|regulation of cell fate commitment|regulation of gene expression|skeletal muscle satellite cell commitment|spinal cord association neuron differentiation|dorsal/ventral neural tube patterning|positive regulation of histone methylation|positive regulation of histone methylation|regulation of protein binding|skeletal muscle tissue regeneration|positive regulation of transcription from RNA polymerase II promoter|neuron fate commitment|embryonic skeletal system development|cartilage development|muscle tissue morphogenesis|positive regulation of myoblast proliferation|",RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0,0,10,0.4,0.0818,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000066113,ADAMTSL1,ADAMTS-like 1,cellular_component|extracellular region|proteinaceous extracellular matrix|,biological_process|,molecular_function|peptidase activity|metallopeptidase activity|zinc ion binding|,9,0,0,9,0,0,0,0,0,0.903,0,0,-1.4,1.8
ENSMUSG00000036961,WNT8B,"wingless-type MMTV integration site family, member 8B",extracellular region|proteinaceous extracellular matrix|extracellular space|,signal transduction|cell-cell signaling|multicellular organismal development|organ morphogenesis|positive regulation of gene expression|negative regulation of gene expression|Wnt signaling pathway|neuron differentiation|cell fate commitment|,receptor binding|frizzled binding|,10,0,0,10,0.2,0.106,0,0,0,0.903,0,0,-1.3,1.6
ENSMUSG00000025408,DDIT3,DNA-damage inducible transcript 3,intracellular|cell|nucleus|nucleus|nucleus|cytoplasm|late endosome|,"blood vessel maturation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|response to stress|ER overload response|ER overload response|response to unfolded protein|cell cycle|cell cycle arrest|Wnt signaling pathway|endoplasmic reticulum unfolded protein response|positive regulation of interleukin-8 production|negative regulation of CREB transcription factor activity|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|response to starvation|mRNA transcription from RNA polymerase II promoter|positive regulation of apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of neuron apoptotic process|regulation of transcription involved in anterior/posterior axis specification|cell redox homeostasis|negative regulation of myoblast differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|release of sequestered calcium ion into cytosol|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of canonical Wnt signaling pathway|negative regulation of determination of dorsal identity|negative regulation of determination of dorsal identity|",DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.9,1
ENSMUSG00000026698,PIGC,"phosphatidylinositol glycan anchor biosynthesis, class C",glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|endoplasmic reticulum|membrane|integral component of membrane|,GPI anchor biosynthetic process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|phosphatidylinositol N-acetylglucosaminyltransferase activity|",10,-0.2,0.334,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000005124,WISP1,WNT1 inducible signaling pathway protein 1,extracellular region|cytoplasm|,regulation of cell growth|cell adhesion|Wnt signaling pathway|,insulin-like growth factor binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000059540,TCEA2,"transcription elongation factor A (SII), 2",nucleus|centrosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|translation|translational elongation|regulation of DNA-templated transcription, elongation|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|translation elongation factor activity|zinc ion binding|metal ion binding|,10,-0.1,0.331,10,0.6,1.63,0,0,0,0.903,0,0,-1,1.8
ENSMUSG00000030717,NUPR1,nuclear protein transcription regulator 1,intracellular|nucleus|cytoplasm|,"acute inflammatory response|transcription, DNA-templated|regulation of transcription, DNA-templated|protein complex assembly|protein acetylation|male gonad development|response to toxic substance|cell growth|positive regulation of protein modification process|skeletal muscle cell differentiation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of apoptotic process|negative regulation of cell cycle|negative regulation of fibroblast proliferation|regulation of female gonad development|",DNA binding|chromatin binding|protein binding|,10,0.7,0.513,10,-0.1,0.257,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000019772,VIP,vasoactive intestinal polypeptide,extracellular region|neuronal cell body|,positive regulation of endothelial cell proliferation|learning or memory|regulation of signal transduction|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|regulation of protein localization|regulation of protein localization|negative regulation of apoptotic process|negative regulation of potassium ion transport|positive regulation of protein catabolic process|positive regulation of protein catabolic process|positive regulation of vasodilation|negative regulation of smooth muscle cell proliferation|regulation of sensory perception of pain|positive regulation of penile erection|,receptor binding|hormone activity|hormone activity|,10,0,0,10,-0.1,0.129,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000094840,A630081J09RIK,RIKEN cDNA A630081J09 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,1.24,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000027570,COL9A3,"collagen, type IX, alpha 3",collagen trimer|collagen type IX trimer|,None,None,9,0,0,9,-1,1.18,0,0,0,0.903,0,0,-2,1
ENSMUSG00000027940,TPM3,"tropomyosin 3, gamma",stress fiber|podosome|cytoplasm|cytoskeleton|growth cone|cortical cytoskeleton|filamentous actin|cleavage furrow|neuron projection|extracellular vesicular exosome|,None,actin binding|protein binding|,10,-0.6,0.0879,10,-0.1,0.128,0,0,0,0.903,0,0,-1.7,1.5
ENSMUSG00000066568,LSM14A,"LSM14 homolog A (SCD6, S. cerevisiae)",cytoplasmic mRNA processing body|cytoplasmic mRNA processing body|intracellular|cytoplasm|cytoplasm|cytoplasm|cytoplasmic stress granule|ribonucleoprotein complex|intracellular membrane-bounded organelle|,regulation of translation|multicellular organismal development|cytoplasmic mRNA processing body assembly|RIG-I signaling pathway|defense response to virus|positive regulation of type I interferon-mediated signaling pathway|,double-stranded DNA binding|double-stranded RNA binding|single-stranded RNA binding|poly(A) RNA binding|,9,0,0,9,-0.1,0.3,0,0,0,0.903,0,0,-1.6,1.5
ENSMUSG00000040723,RCSD1,RCSD domain containing 1,cellular_component|,cellular hyperosmotic response|,actin filament binding|,10,0,0,10,0.3,0.17,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000026418,TNNI1,"troponin I, skeletal, slow 1",troponin complex|,regulation of muscle contraction|ventricular cardiac muscle tissue morphogenesis|,actin binding|metal ion binding|,10,-0.2,0.121,10,0,0,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000018263,TBX5,T-box 5,nucleus|nucleus|transcription factor complex|cytoplasm|,"morphogenesis of an epithelium|bundle of His development|atrioventricular valve morphogenesis|endocardial cushion development|cardiac left ventricle formation|ventricular cardiac muscle tissue development|ventricular septum development|atrial septum development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell-cell signaling|multicellular organismal development|pattern specification process|heart development|heart development|negative regulation of cell proliferation|apoptotic nuclear changes|lung development|embryonic limb morphogenesis|embryonic limb morphogenesis|embryonic limb morphogenesis|negative regulation of cell migration|embryonic forelimb morphogenesis|embryonic forelimb morphogenesis|forelimb morphogenesis|forelimb morphogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of cardioblast differentiation|cardiac muscle cell differentiation|cardiac muscle cell differentiation|pericardium development|negative regulation of cardiac muscle cell proliferation|positive regulation of cardiac muscle cell proliferation|transdifferentiation|atrial septum morphogenesis|positive regulation of secondary heart field cardioblast proliferation|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|,10,0,0,10,-0.2,0.141,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000030516,TJP1,tight junction protein 1,nucleus|cytoplasm|cytoplasm|plasma membrane|plasma membrane|cell-cell junction|adherens junction|cell-cell adherens junction|gap junction|tight junction|tight junction|cell surface|intercalated disc|membrane|basolateral plasma membrane|apical plasma membrane|apicolateral plasma membrane|cell junction|cell junction|apical junction complex|apical part of cell|apical part of cell|intercellular canaliculus|,blastocyst formation|sensory perception of sound|,protein binding|calmodulin binding|protein C-terminus binding|protein domain specific binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.6,1.5
ENSMUSG00000058755,OSM,oncostatin M,extracellular region|extracellular space|oncostatin-M receptor complex|,immune response|peripheral nervous system development|positive regulation of cell proliferation|response to heat|positive regulation of peptidyl-serine phosphorylation|regulation of growth|tyrosine phosphorylation of Stat3 protein|tyrosine phosphorylation of Stat5 protein|tyrosine phosphorylation of Stat1 protein|positive regulation of MAPK cascade|negative regulation of meiosis|positive regulation of transcription from RNA polymerase II promoter|negative regulation of hormone secretion|behavioral response to pain|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of apoptotic signaling pathway|,cytokine activity|cytokine activity|oncostatin-M receptor binding|growth factor activity|,10,0.9,1.04,10,-0.2,0.925,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000052397,EZR,ezrin,ruffle|uropod|extracellular space|intracellular|nucleolus|cytoplasm|cytosol|cytoskeleton|actin filament|plasma membrane|plasma membrane|microvillus|microvillus|focal adhesion|actin cytoskeleton|membrane|membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|extrinsic component of membrane|filopodium|T-tubule|microvillus membrane|ciliary basal body|cell projection|cell body|microspike|membrane raft|apical part of cell|apical part of cell|cell tip|extracellular vesicular exosome|astrocyte projection|Schwann cell microvillus|,regulation of cell shape|positive regulation of gene expression|receptor internalization|establishment or maintenance of apical/basal cell polarity|filopodium assembly|actin filament bundle assembly|establishment of endothelial barrier|,actin binding|protein binding|cytoskeletal protein binding|protein domain specific binding|protein complex binding|poly(A) RNA binding|cell adhesion molecule binding|actin filament binding|,10,-0.1,0.0069,10,0.1,0.0577,0,0,0,0.903,0,0,-1.2,1.7
ENSMUSG00000073007,FAM46D,"family with sequence similarity 46, member D",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.417,0,0,0,0.903,0,0,-1.2,1.6
ENSMUSG00000049176,FRMPD4,FERM and PDZ domain containing 4,cytoskeleton|cell projection|dendritic spine|,positive regulation of synapse structural plasticity|,"phosphatidylinositol-4,5-bisphosphate binding|lipid binding|",10,-0.8,0.254,10,0.2,0.622,0,0,0,0.903,0,0,-1.6,1.7
ENSMUSG00000015697,SETDB1,"SET domain, bifurcated 1",nuclear chromatin|nucleus|nucleus|chromosome|cytoplasm|Golgi apparatus|plasma membrane|,"negative regulation of transcription from RNA polymerase II promoter|inner cell mass cell proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|methylation|histone lysine methylation|histone H3-K9 trimethylation|bone development|",DNA binding|protein binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|metal ion binding|,10,0.2,0.157,10,0,0,0,0,0,0.903,0,0,-1.1,1.9
ENSMUSG00000028207,ASPH,aspartate-beta-hydroxylase,cytoplasm|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|cortical endoplasmic reticulum|,"pattern specification process|negative regulation of cell proliferation|positive regulation of calcium ion transport into cytosol|peptidyl-amino acid modification|regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|regulation of protein stability|activation of store-operated calcium channel activity|response to ATP|limb morphogenesis|peptidyl-aspartic acid hydroxylation|positive regulation of proteolysis|positive regulation of transcription, DNA-templated|cytosolic calcium ion homeostasis|oxidation-reduction process|palate development|face morphogenesis|calcium ion transmembrane transport|cellular response to calcium ion|positive regulation of intracellular protein transport|activation of cysteine-type endopeptidase activity|regulation of protein depolymerization|",peptide-aspartate beta-dioxygenase activity|calcium ion binding|protein binding|oxidoreductase activity|metal ion binding|dioxygenase activity|,10,0,0,10,-0.5,1.5,0,0,0,0.903,0,0,-2,0.8
ENSMUSG00000057777,MAB21L2,mab-21-like 2 (C. elegans),nucleus|,multicellular organismal development|positive regulation of cell proliferation|embryonic body morphogenesis|camera-type eye development|,None,10,0,0,10,0.6,0.583,0,0,0,0.903,0,0,-0.8,2
ENSMUSG00000024913,LRP5,low density lipoprotein receptor-related protein 5,mitochondrion|endoplasmic reticulum|plasma membrane|plasma membrane|membrane|integral component of membrane|receptor complex|receptor complex|,"gastrulation with mouth forming second|vasculature development|positive regulation of mesenchymal cell proliferation|osteoblast development|glucose catabolic process|endocytosis|multicellular organismal development|cholesterol metabolic process|regulation of blood pressure|positive regulation of cell proliferation|anterior/posterior pattern specification|Wnt signaling pathway|Wnt signaling pathway|Wnt signaling pathway|regulation of ossification|positive regulation of osteoblast proliferation|somatic stem cell maintenance|limb morphogenesis|extracellular matrix-cell signaling|cell migration involved in gastrulation|cholesterol homeostasis|cholesterol homeostasis|embryonic digit morphogenesis|regulation of apoptotic process|Wnt signaling pathway involved in dorsal/ventral axis specification|Wnt signaling pathway involved in dorsal/ventral axis specification|regulation of fat cell differentiation|positive regulation of fat cell differentiation|negative regulation of osteoblast differentiation|positive regulation of mitosis|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|bone remodeling|bone remodeling|regulation of bone remodeling|bone marrow development|bone marrow development|embryonic camera-type eye morphogenesis|positive regulation of sequence-specific DNA binding transcription factor activity|anatomical structure regression|retina morphogenesis in camera-type eye|embryonic retina morphogenesis in camera-type eye|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|bone development|bone morphogenesis|bone morphogenesis|branching involved in mammary gland duct morphogenesis|mammary gland duct morphogenesis|adipose tissue development|adipose tissue development|cell-cell signaling involved in mammary gland development|regulation of canonical Wnt signaling pathway|regulation of insulin secretion involved in cellular response to glucose stimulus|retina vasculature morphogenesis in camera-type eye|retina vasculature morphogenesis in camera-type eye|retinal blood vessel morphogenesis|retinal blood vessel morphogenesis|negative regulation of protein serine/threonine kinase activity|apoptotic process involved in patterning of blood vessels|",protein binding|coreceptor activity|Wnt-protein binding|Wnt-activated receptor activity|,10,0,0,10,0.1,0.043,0,0,0,0.903,0,0,-1.4,1.7
ENSMUSG00000015337,ENDOG,endonuclease G,mitochondrion|,in utero embryonic development|DNA catabolic process|apoptotic DNA fragmentation|response to tumor necrosis factor|positive regulation of apoptotic process|positive regulation of apoptotic process|response to antibiotic|nucleic acid phosphodiester bond hydrolysis|,nucleic acid binding|nuclease activity|endonuclease activity|hydrolase activity|metal ion binding|,10,-0.1,0.0415,10,0.3,0.0582,0,0,0,0.903,0,0,-1.4,1.5
ENSMUSG00000031441,ATP11A,"ATPase, class VI, type 11A",lysosomal membrane|endosome|endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|recycling endosome|,transport|cation transport|lipid transport|phospholipid transport|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-2,0.8
ENSMUSG00000021594,SRD5A1,steroid 5 alpha-reductase 1,cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|neuronal cell body|myelin sheath|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|cell body fiber|,lipid metabolic process|steroid biosynthetic process|androgen biosynthetic process|androgen biosynthetic process|sex differentiation|steroid metabolic process|androgen metabolic process|cell differentiation|progesterone metabolic process|response to drug|oxidation-reduction process|,"3-oxo-5-alpha-steroid 4-dehydrogenase activity|3-oxo-5-alpha-steroid 4-dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|amide binding|cholestenone 5-alpha-reductase activity|NADPH binding|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000038884,A230050P20RIK,RIKEN cDNA A230050P20 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,0.948,10,0,0,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000028176,LRRC7,leucine rich repeat containing 7,cytoplasm|plasma membrane|postsynaptic density|actin cytoskeleton|membrane|cell junction|filopodium|neuron projection|axon initial segment|dendritic spine|synapse|postsynaptic membrane|,positive regulation of neuron projection development|,protein C-terminus binding|,10,0,0,10,0.1,0.188,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000037646,VPS13B,vacuolar protein sorting 13B (yeast),cellular_component|,transport|biological_process|protein transport|,molecular_function|,10,0.1,0.000452,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000022218,TGM1,"transglutaminase 1, K polypeptide",cell-cell adherens junction|membrane|intrinsic component of membrane|extracellular vesicular exosome|,organ morphogenesis|peptide cross-linking|protein metabolic process|keratinocyte differentiation|keratinization|,"protein-glutamine gamma-glutamyltransferase activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1.4,1.7
ENSMUSG00000021779,THRB,thyroid hormone receptor beta,nuclear chromatin|nucleus|nucleus|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|sensory perception of sound|negative regulation of female receptivity|regulation of heart contraction|female courtship behavior|positive regulation of cell proliferation|organ morphogenesis|regulation of lipid metabolic process|intracellular receptor signaling pathway|intracellular receptor signaling pathway|positive regulation of chondrocyte differentiation|steroid hormone mediated signaling pathway|positive regulation of ossification|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|Type I pneumocyte differentiation|regulation of cholesterol metabolic process|regulation of triglyceride metabolic process|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|thyroid hormone receptor activity|thyroid hormone receptor activity|protein binding|zinc ion binding|enzyme binding|chromatin DNA binding|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|thyroid hormone binding|,10,0.9,0.0953,10,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000027528,FABP9,"fatty acid binding protein 9, testis",acrosomal vesicle|cytoplasm|,transport|,transporter activity|lipid binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000074682,ZCCHC3,"zinc finger, CCHC domain containing 3",cellular_component|,biological_process|,poly(A) RNA binding|metal ion binding|,10,0.1,0.0152,10,0,0,0,0,0,0.903,0,0,-1.3,1.6
ENSMUSG00000049721,GAL3ST1,galactose-3-O-sulfotransferase 1,Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|galactosylceramide biosynthetic process|spermatogenesis|biosynthetic process|glycolipid biosynthetic process|myelination|,galactosylceramide sulfotransferase activity|transferase activity|,10,0,0,10,0.2,0.107,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000044006,CILP2,cartilage intermediate layer protein 2,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.618,0,0,0,0.903,0,0,-1.9,1.1
ENSMUSG00000010660,PLCD1,"phospholipase C, delta 1",nucleus|cytoplasm|cytoplasm|cytosol|cytosol|membrane|mitochondrial membrane|membrane raft|extracellular vesicular exosome|,angiogenesis|lipid metabolic process|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of norepinephrine secretion|lipid catabolic process|positive regulation of inositol trisphosphate biosynthetic process|intracellular signal transduction|regulation of cell proliferation|response to peptide hormone|cytosolic calcium ion homeostasis|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|response to calcium ion|labyrinthine layer blood vessel development|regulation of phospholipase C activity|,"phosphatidylserine binding|phosphatidylinositol phospholipase C activity|phospholipase C activity|signal transducer activity|calcium ion binding|protein binding|phospholipid binding|phosphatidylinositol-4,5-bisphosphate binding|phosphoric diester hydrolase activity|hydrolase activity|GTPase activating protein binding|metal ion binding|phosphatidic acid binding|phosphatidylinositol phosphate binding|",10,0,0,10,-0.2,0.21,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000020811,WSCD1,WSC domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|sulfotransferase activity|,10,-0.1,0.0223,10,0.3,0.513,0,0,0,0.903,0,0,-1.1,1.7
ENSMUSG00000038872,ZFHX3,zinc finger homeobox 3,nucleus|transcription factor complex|cytoplasm|mitochondrion|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|muscle organ development|negative regulation of myoblast differentiation|positive regulation of myoblast differentiation|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|zinc ion binding|enzyme binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,-1,1.76,10,-0.1,0.0705,0,0,0,0.903,0,0,-2,0.7
ENSMUSG00000001150,MCM3AP,minichromosome maintenance deficient 3 (S. cerevisiae) associated protein,nucleus|nucleus|nuclear pore|cytoplasm|cytosol|,immune system process|transport|protein transport|mRNA transport|,None,10,-0.3,0.87,10,0.5,1.43,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000059383,GFRAL,GDNF family receptor alpha like,intracellular|plasma membrane|membrane|integral component of membrane|,stress-activated protein kinase signaling cascade|negative regulation of neuron apoptotic process|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,molecular_function|,10,0,0,10,-0.7,0.764,0,0,0,0.903,0,0,-1.9,1.1
ENSMUSG00000038126,MPHOSPH9,M-phase phosphoprotein 9,cytoplasm|Golgi apparatus|centrosome|centriole|cytoskeleton|plasma membrane|membrane|membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000027857,TSHB,"thyroid stimulating hormone, beta subunit",extracellular region|,None,hormone activity|,10,0.1,0.0268,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000029722,AGFG2,ArfGAP with FG repeats 2,membrane|,biological_process|regulation of ARF GTPase activity|,molecular_function|ARF GTPase activator activity|zinc ion binding|metal ion binding|,10,-1.1,1.77,10,0,0,0,0,0,0.903,0,0,-2,0.8
ENSMUSG00000024501,DPYSL3,dihydropyrimidinase-like 3,extracellular space|cytoplasm|cytosol|lamellipodium|growth cone|filamentous actin|cell projection|cell body|exocytic vesicle|,pyrimidine nucleobase catabolic process|nervous system development|positive regulation of neuron projection development|negative regulation of neuron projection development|negative regulation of cell migration|actin filament bundle assembly|protein homooligomerization|positive regulation of filopodium assembly|actin crosslink formation|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|SH3 domain binding|chondroitin sulfate binding|phosphoprotein binding|",10,0,0,10,-0.1,0.166,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000069922,CES3A,carboxylesterase 3A,endoplasmic reticulum|extracellular vesicular exosome|,biological_process|,hydrolase activity|carboxylic ester hydrolase activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000022505,EMP2,epithelial membrane protein 2,membrane|integral component of membrane|apical plasma membrane|,positive regulation of cell-matrix adhesion|positive regulation of integrin-mediated signaling pathway|positive regulation of integrin-mediated signaling pathway|,integrin binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000029759,PON3,paraoxonase 3,extracellular region|extracellular space|intracellular membrane-bounded organelle|extracellular vesicular exosome|,phenylacetate catabolic process|aromatic compound catabolic process|coumarin catabolic process|carboxylic acid catabolic process|,"aryldialkylphosphatase activity|arylesterase activity|hydrolase activity|3,4-dihydrocoumarin hydrolase activity|protein homodimerization activity|metal ion binding|dihydrocoumarin hydrolase activity|",10,0.7,0.126,10,0,0,0,0,0,0.903,0,0,-1.1,2
ENSMUSG00000090112,SHPRH,SNF2 histone linker PHD RING helicase,nucleosome|cellular_component|nucleus|,protein polyubiquitination|DNA repair|nucleosome assembly|cellular response to DNA damage stimulus|,"nucleotide binding|DNA binding|helicase activity|ubiquitin-protein transferase activity|ATP binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|hydrolase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.1,0.15,0,0,0,0.903,0,0,-1.9,1.1
ENSMUSG00000029380,CXCL1,chemokine (C-X-C motif) ligand 1,extracellular region|extracellular space|extracellular space|,response to molecule of bacterial origin|acute inflammatory response|inflammatory response|immune response|positive regulation of cytosolic calcium ion concentration|positive regulation of sodium ion transport|neutrophil chemotaxis|positive regulation of potassium ion transport|,cytokine activity|chemokine activity|growth factor activity|,10,-0.1,0.0285,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000030094,XPC,"xeroderma pigmentosum, complementation group C",nucleus|nucleus|nucleolus|cytoplasm|plasma membrane|extracellular vesicular exosome|XPC complex|,"nucleotide-excision repair, DNA damage recognition|DNA repair|nucleotide-excision repair|nucleotide-excision repair|nucleotide-excision repair|cellular response to DNA damage stimulus|response to UV-B|intra-S DNA damage checkpoint|regulation of mitotic cell cycle phase transition|",DNA binding|damaged DNA binding|single-stranded DNA binding|,10,0,0,10,0.1,0.191,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000060260,PWWP2B,PWWP domain containing 2B,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.596,10,0,0,0,0,0,0.903,0,0,-1.1,1.9
ENSMUSG00000027506,TPD52,tumor protein D52,cytoplasm|endoplasmic reticulum|perinuclear region of cytoplasm|,positive regulation of cell proliferation|,calcium ion binding|protein binding|protein homodimerization activity|protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.6
ENSMUSG00000028978,NOS3,"nitric oxide synthase 3, endothelial cell",nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|mitochondrion|Golgi apparatus|cytosol|cytosol|cytoskeleton|plasma membrane|caveola|vesicle membrane|membrane|sarcolemma|membrane raft|apical part of cell|,angiogenesis|ovulation from ovarian follicle|in utero embryonic development|blood vessel remodeling|regulation of sodium ion transport|regulation of the force of heart contraction by chemical signal|regulation of systemic arterial blood pressure by endothelin|arginine catabolic process|nitric oxide biosynthetic process|nitric oxide biosynthetic process|signal transduction|nitric oxide mediated signal transduction|negative regulation of cell proliferation|negative regulation of muscle hyperplasia|smooth muscle hyperplasia|lung development|positive regulation of guanylate cyclase activity|positive regulation of guanylate cyclase activity|lipopolysaccharide-mediated signaling pathway|response to estradiol|positive regulation of apoptotic process|negative regulation of potassium ion transport|endothelial cell migration|positive regulation of angiogenesis|negative regulation of blood pressure|positive regulation of vasodilation|negative regulation of smooth muscle cell proliferation|regulation of blood vessel size|negative regulation of hydrolase activity|negative regulation of calcium ion transport|oxidation-reduction process|cellular response to mechanical stimulus|cellular response to transforming growth factor beta stimulus|,actin binding|actin monomer binding|NADPH-hemoprotein reductase activity|nitric-oxide synthase activity|nitric-oxide synthase activity|iron ion binding|calmodulin binding|beta-catenin binding|FMN binding|oxidoreductase activity|heme binding|tetrahydrobiopterin binding|arginine binding|cadherin binding|metal ion binding|flavin adenine dinucleotide binding|NADP binding|nitric-oxide synthase binding|Hsp90 protein binding|scaffold protein binding|,10,-0.2,0.648,10,0,0,0,0,0,0.903,0,0,-1.9,1.2
ENSMUSG00000055653,GPC3,glypican 3,extracellular region|proteinaceous extracellular matrix|lysosome|plasma membrane|integral component of plasma membrane|membrane|anchored component of membrane|anchored component of plasma membrane|extracellular vesicular exosome|,"branching involved in ureteric bud morphogenesis|kidney development|negative regulation of cell proliferation|organ morphogenesis|anterior/posterior axis specification|body morphogenesis|negative regulation of peptidase activity|bone mineralization|osteoclast differentiation|lung development|positive regulation of BMP signaling pathway|embryonic hindlimb morphogenesis|regulation of growth|regulation of growth|positive regulation of protein catabolic process|positive regulation of endocytosis|negative regulation of smoothened signaling pathway|negative regulation of smoothened signaling pathway|positive regulation of smoothened signaling pathway|negative regulation of growth|positive regulation of glucose import|negative regulation of epithelial cell proliferation|coronary vasculature development|cell proliferation involved in kidney development|mesenchymal cell proliferation involved in ureteric bud development|mesonephric duct morphogenesis|cell proliferation involved in metanephros development|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|positive regulation of Wnt signaling pathway, planar cell polarity pathway|positive regulation of Wnt signaling pathway, planar cell polarity pathway|",protein binding|peptidase inhibitor activity|heparan sulfate proteoglycan binding|peptidyl-dipeptidase inhibitor activity|,10,0.1,0.23,10,0,0,0,0,0,0.903,0,0,-1.5,1.6
ENSMUSG00000016933,PLCG1,"phospholipase C, gamma 1",ruffle|cytoplasm|cytosol|plasma membrane|cell-cell junction|COP9 signalosome|lamellipodium|cell projection|neuron projection|,in utero embryonic development|lipid metabolic process|calcium ion transport|signal transduction|epidermal growth factor receptor signaling pathway|protein secretion|phospholipid catabolic process|positive regulation of epithelial cell migration|lipid catabolic process|cell migration|calcium-mediated signaling|inositol trisphosphate biosynthetic process|intracellular signal transduction|positive regulation of blood vessel endothelial cell migration|positive regulation of angiogenesis|T cell receptor signaling pathway|positive regulation of release of sequestered calcium ion into cytosol|cellular response to epidermal growth factor stimulus|regulation of store-operated calcium channel activity|,phosphatidylinositol phospholipase C activity|signal transducer activity|insulin receptor binding|neurotrophin TRKA receptor binding|calcium ion binding|protein binding|phosphoric diester hydrolase activity|hydrolase activity|protein kinase binding|receptor tyrosine kinase binding|glutamate receptor binding|metal ion binding|phosphoprotein binding|,10,0,0,10,-0.3,0.961,0,0,0,0.903,0,0,-1.9,1
ENSMUSG00000050567,MAML1,mastermind like 1 (Drosophila),MAML1-RBP-Jkappa- ICN1 complex|nucleus|nucleus|nucleus|nuclear speck|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|positive regulation of transcription of Notch receptor target|positive regulation of myotube differentiation|positive regulation of myotube differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of muscle cell differentiation|atrioventricular node cell development|",transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|protein kinase binding|peptide antigen binding|,10,0,0,10,-0.1,0.0118,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000031613,HPGD,hydroxyprostaglandin dehydrogenase 15 (NAD),cytoplasm|basolateral plasma membrane|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|prostaglandin metabolic process|transforming growth factor beta receptor signaling pathway|G-protein coupled receptor signaling pathway|female pregnancy|parturition|metabolic process|negative regulation of cell cycle|oxidation-reduction process|ductus arteriosus closure|,catalytic activity|prostaglandin E receptor activity|15-hydroxyprostaglandin dehydrogenase (NAD+) activity|15-hydroxyprostaglandin dehydrogenase (NAD+) activity|oxidoreductase activity|NAD binding|NAD+ binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.1,1.9
ENSMUSG00000022383,PPARA,peroxisome proliferator activated receptor alpha,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|response to hypoxia|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|lipid metabolic process|fatty acid metabolic process|fatty acid metabolic process|fatty acid metabolic process|epidermis development|regulation of gene expression|negative regulation of macrophage derived foam cell differentiation|negative regulation of receptor biosynthetic process|negative regulation of cholesterol storage|negative regulation of sequestering of triglyceride|regulation of fatty acid metabolic process|intracellular receptor signaling pathway|negative regulation of protein binding|negative regulation of appetite|response to insulin|circadian regulation of gene expression|behavioral response to nicotine|wound healing|lipoprotein metabolic process|regulation of circadian rhythm|steroid hormone mediated signaling pathway|positive regulation of gluconeogenesis|negative regulation of blood pressure|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fatty acid oxidation|rhythmic process|enamel mineralization|regulation of glycolytic by positive regulation of transcription from RNA polymerase II promoter|regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter|regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter|negative regulation of neuron death|negative regulation of transcription regulatory region DNA binding|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II repressing transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|steroid hormone receptor activity|receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|drug binding|zinc ion binding|lipid binding|lipid binding|phosphatase binding|protein domain specific binding|ubiquitin conjugating enzyme binding|protein complex binding|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|NFAT protein binding|MDM2/MDM4 family protein binding|,10,-0.7,0.223,10,0.2,0.412,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000034101,CTNND1,"catenin (cadherin associated protein), delta 1",nucleus|cytoplasm|cytosol|plasma membrane|plasma membrane|cell-cell junction|cell-cell adherens junction|zonula adherens|tight junction|membrane|lamellipodium|lamellipodium|growth cone|midbody|dendritic spine|synapse|extracellular vesicular exosome|,"morphogenesis of a polarized epithelium|transcription, DNA-templated|regulation of transcription, DNA-templated|cell adhesion|salivary gland morphogenesis|Wnt signaling pathway|single organismal cell-cell adhesion|keratinocyte differentiation|epithelial cell differentiation involved in salivary gland development|negative regulation of canonical Wnt signaling pathway|",receptor binding|protein binding|protein kinase binding|protein phosphatase binding|protein domain specific binding|cadherin binding|cell adhesion molecule binding|,9,0,0,9,0,0,0,0,0,0.903,0,0,-1.6,1.6
ENSMUSG00000051228,NYX,nyctalopin,extracellular region|proteinaceous extracellular matrix|intracellular|,visual perception|response to stimulus|,None,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000015222,MAP2,microtubule-associated protein 2,intracellular|cytoplasm|smooth endoplasmic reticulum|rough endoplasmic reticulum|cytoskeleton|microtubule|microtubule associated complex|dendrite|dendrite|nuclear periphery|neuron projection|neuron projection|neuronal cell body|neuronal cell body|dendritic shaft|protein complex|cell body|,microtubule bundle formation|axonogenesis|axonogenesis|dendrite development|cellular response to organic substance|,dystroglycan binding|protein binding|calmodulin binding|cytoskeletal regulatory protein binding|microtubule binding|tubulin binding|,10,0,0,10,0.1,0.0203,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000006288,TTC5,tetratricopeptide repeat domain 5,nucleus|nucleus|cytoplasm|,DNA repair|cellular response to DNA damage stimulus|positive regulation of transcription from RNA polymerase II promoter|,DNA binding|chromatin binding|,10,0.2,0.0411,10,-0.1,0.237,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000038775,VILL,villin-like,cellular_component|,cytoskeleton organization|actin filament capping|,actin binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.8
ENSMUSG00000027306,NUSAP1,nucleolar and spindle associated protein 1,cell|nucleus|chromosome|nucleolus|nucleolus|cytoplasm|spindle|cytoskeleton|microtubule|spindle microtubule|,mitotic sister chromatid segregation|microtubule cytoskeleton organization|mitotic cytokinesis|cell cycle|mitotic nuclear division|mitotic chromosome condensation|establishment of mitotic spindle localization|positive regulation of mitosis|cell division|,DNA binding|microtubule binding|poly(A) RNA binding|,10,0,0,10,-0.1,0.148,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000030699,TBX6,T-box 6,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|mesoderm formation|cell fate specification|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|negative regulation of neuron projection development|negative regulation of neuron maturation|signal transduction involved in regulation of gene expression|somite rostral/caudal axis specification|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription factor binding|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|,10,0,0,10,-0.1,0.252,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000056367,ACTR3B,ARP3 actin-related protein 3B,cellular_component|cytoplasm|cytoskeleton|cell projection|,biological_process|,nucleotide binding|molecular_function|actin binding|ATP binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.9,1.4
ENSMUSG00000056214,PARD6G,par-6 family cell polarity regulator gamma,cytoplasm|plasma membrane|tight junction|membrane|cell junction|protein complex|,cell cycle|cell division|,None,10,0,0,10,0.1,0.0772,0,0,0,0.903,0,0,-1.3,1.6
ENSMUSG00000004296,IL12B,interleukin 12b,extracellular region|extracellular space|extracellular space|cytoplasm|membrane|interleukin-12 complex|interleukin-12 complex|interleukin-12 complex|interleukin-23 complex|,positive regulation of T cell mediated cytotoxicity|positive regulation of defense response to virus by host|positive regulation of defense response to virus by host|natural killer cell activation involved in immune response|positive regulation of T-helper 1 type immune response|positive regulation of T-helper 1 type immune response|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|negative regulation of inflammatory response to antigenic stimulus|cell cycle arrest|cell surface receptor signaling pathway|response to UV-B|positive regulation of activation of JAK2 kinase activity|cell migration|sensory perception of pain|natural killer cell activation|negative regulation of interleukin-10 production|negative regulation of interleukin-17 production|positive regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of interferon-gamma production|positive regulation of interferon-gamma production|positive regulation of interferon-gamma production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-17 production|positive regulation of tumor necrosis factor production|positive regulation of natural killer cell activation|positive regulation of natural killer cell proliferation|positive regulation of mononuclear cell proliferation|positive regulation of smooth muscle cell apoptotic process|T-helper cell differentiation|positive regulation of T cell proliferation|positive regulation of T cell proliferation|positive regulation of activated T cell proliferation|regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat4 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|defense response to protozoan|defense response to protozoan|negative regulation of growth of symbiont in host|positive regulation of osteoclast differentiation|positive regulation of cell adhesion|negative regulation of smooth muscle cell proliferation|positive regulation of lymphocyte proliferation|defense response to Gram-negative bacterium|positive regulation of NK T cell activation|positive regulation of NK T cell proliferation|defense response to virus|cellular response to lipopolysaccharide|cellular response to interferon-gamma|,cytokine receptor activity|cytokine activity|cytokine activity|cytokine receptor binding|protein binding|growth factor activity|interleukin-12 alpha subunit binding|interleukin-12 alpha subunit binding|identical protein binding|protein homodimerization activity|interleukin-23 receptor binding|protein heterodimerization activity|,10,0.1,0.151,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000040610,TLX3,"T cell leukemia, homeobox 3",nucleus|,"cell fate specification|cell fate specification|neuron migration|regulation of respiratory gaseous exchange by neurological system process|regulation of transcription, DNA-templated|multicellular organismal development|central nervous system development|respiratory gaseous exchange|neuron differentiation|negative regulation of neuron differentiation|neuron fate specification|",DNA binding|protein binding|sequence-specific DNA binding|,10,0,0,10,-0.4,1.45,0,0,0,0.903,0,0,-2,0.8
ENSMUSG00000031161,HDAC6,histone deacetylase 6,histone deacetylase complex|nucleus|nucleus|cytoplasm|cytosol|microtubule|microtubule associated complex|cytoplasmic microtubule|caveola|inclusion body|aggresome|dynein complex|axon|dendrite|cell leading edge|perikaryon|protein complex|perinuclear region of cytoplasm|,"protein polyubiquitination|transcription, DNA-templated|regulation of transcription, DNA-templated|protein deacetylation|protein deacetylation|ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|misfolded or incompletely synthesized protein catabolic process|intracellular protein transport|negative regulation of microtubule depolymerization|response to toxic substance|positive regulation of signal transduction|response to organic substance|regulation of receptor activity|positive regulation of epithelial cell migration|positive regulation of receptor biosynthetic process|macroautophagy|chromatin modification|histone deacetylation|histone deacetylation|lysosome localization|peptidyl-lysine deacetylation|cellular response to topologically incorrect protein|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|protein complex disassembly|negative regulation of protein complex disassembly|regulation of fat cell differentiation|negative regulation of proteolysis|response to misfolded protein|regulation of establishment of protein localization|cellular response to hydrogen peroxide|aggresome assembly|aggresome assembly|polyubiquitinated misfolded protein transport|Hsp90 deacetylation|Hsp90 deacetylation|response to growth factor|cellular response to misfolded protein|positive regulation of chaperone-mediated protein complex assembly|tubulin deacetylation|tubulin deacetylation|tubulin deacetylation|positive regulation of hydrogen peroxide-mediated programmed cell death|",actin binding|histone deacetylase activity|histone deacetylase activity|protein binding|beta-catenin binding|microtubule binding|microtubule binding|zinc ion binding|hydrolase activity|histone deacetylase activity (H3-K14 specific)|polyubiquitin binding|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|histone deacetylase activity (H4-K16 specific)|histone deacetylase binding|tubulin deacetylase activity|tubulin deacetylase activity|alpha-tubulin binding|ubiquitin binding|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|tau protein binding|beta-tubulin binding|Hsp90 protein binding|dynein complex binding|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,0.2,0.077,10,-0.2,0.299,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000030102,ITPR1,"inositol 1,4,5-trisphosphate receptor 1",intracellular|cell|nuclear envelope|nuclear envelope|nuclear inner membrane|nucleolus|cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|plasma membrane|calcineurin complex|postsynaptic density|postsynaptic density|membrane|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|dendrite|secretory granule membrane|platelet dense granule membrane|platelet dense tubular network|neuronal cell body|intracellular membrane-bounded organelle|protein complex|protein complex|membrane raft|perinuclear region of cytoplasm|synaptic membrane|,response to hypoxia|response to hypoxia|transport|ion transport|calcium ion transport|apoptotic process|positive regulation of cytosolic calcium ion concentration|post-embryonic development|endoplasmic reticulum calcium ion homeostasis|inositol phosphate-mediated signaling|inositol phosphate-mediated signaling|voluntary musculoskeletal movement|release of sequestered calcium ion into cytosol|release of sequestered calcium ion into cytosol|positive regulation of calcium ion transport|transmembrane transport|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|calcium ion transmembrane transport|cellular response to cAMP|negative regulation of neuron death|,"ion channel activity|intracellular ligand-gated calcium channel activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|calcium channel activity|protein binding|protein C-terminus binding|protein phosphatase binding|protein complex binding|phosphatidylinositol binding|",10,0.3,0.692,10,-0.4,0.318,0,0,0,0.903,0,0,-1.7,1.4
ENSMUSG00000031870,PGR,progesterone receptor,nucleus|nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|cytosol|plasma membrane|axon|dendrite|neuron projection|dendritic spine|perikaryon|axon terminus|,"ovulation from ovarian follicle|epithelial cell maturation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|positive regulation of smooth muscle cell migration|intracellular receptor signaling pathway|mammary gland development|response to cocaine|negative regulation of apoptotic process|steroid hormone mediated signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of epithelial cell proliferation|progesterone receptor signaling pathway|female mating behavior|tertiary branching involved in mammary gland duct morphogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|receptor binding|steroid binding|protein binding|zinc ion binding|lipid binding|enzyme binding|hormone binding|sequence-specific DNA binding|metal ion binding|,10,0.3,0.499,10,0,0,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000015957,WNT11,"wingless-type MMTV integration site family, member 11",extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|cytoplasm|extracellular matrix|,"osteoblast differentiation|kidney development|outflow tract morphogenesis|protein phosphorylation|signal transduction|cell-cell signaling|multicellular organismal development|organ morphogenesis|positive regulation of gene expression|Wnt signaling pathway|neuron differentiation|bone mineralization|negative regulation of cell growth|positive regulation of cell migration|negative regulation of cell migration|positive regulation of Ras GTPase activity|positive regulation of transforming growth factor beta2 production|protein localization to cell surface|non-canonical Wnt signaling pathway|positive regulation of apoptotic process|negative regulation of apoptotic process|cell fate commitment|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|artery morphogenesis|positive regulation of stress fiber assembly|palate development|palate development|canonical Wnt signaling pathway|ventricular septum morphogenesis|negative regulation of cell death|neuroendocrine cell differentiation|tight junction assembly|negative regulation of mesenchymal cell proliferation|positive regulation of protein kinase C signaling|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of fibroblast growth factor production|",Ras GTPase activator activity|receptor binding|frizzled binding|protein binding|protein kinase activator activity|transcription regulatory region DNA binding|,10,-0.2,0.069,10,0,0,0,0,0,0.903,0,0,-2,0.9
ENSMUSG00000031955,BCAR1,breast cancer anti-estrogen resistance 1,ruffle|nucleolus|cytoplasm|plasma membrane|plasma membrane|focal adhesion|focal adhesion|actin cytoskeleton|lamellipodium|cell junction|,actin filament organization|cell adhesion|epidermal growth factor receptor signaling pathway|G-protein coupled receptor signaling pathway|integrin-mediated signaling pathway|insulin receptor signaling pathway|positive regulation of endothelial cell migration|cell migration|cell migration|actin cytoskeleton organization|positive regulation of cell migration|cellular response to hepatocyte growth factor stimulus|platelet-derived growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|neurotrophin TRK receptor signaling pathway|hepatocyte growth factor receptor signaling pathway|antigen receptor-mediated signaling pathway|B cell receptor signaling pathway|cell chemotaxis|,signal transducer activity|protein binding|SH3 domain binding|protein kinase binding|protein domain specific binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.6,1.5
ENSMUSG00000035437,RABGAP1,RAB GTPase activating protein 1,cellular_component|cytoplasm|cytoskeleton|,cell cycle|biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,0,0,10,0.1,0.014,0,0,0,0.903,0,0,-1.1,2
ENSMUSG00000044066,CEP68,centrosomal protein 68,cytoplasm|centrosome|cytoskeleton|,centriole-centriole cohesion|protein localization to organelle|centrosome organization|,protein kinase binding|protein domain specific binding|,10,0.1,0.245,10,0,0,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000029026,TRP73,transformation related protein 73,chromatin|chromatin|nucleus|nucleus|transcription factor complex|cytoplasm|cytosol|,"negative regulation of transcription from RNA polymerase II promoter|activation of MAPK activity|release of cytochrome c from mitochondria|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|inflammatory response|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cell cycle|cell cycle arrest|post-embryonic development|response to X-ray|response to gamma radiation|hippocampus development|forebrain development|mitotic G1 DNA damage checkpoint|cerebrospinal fluid secretion|cellular response to UV|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of apoptotic process|negative regulation of JUN kinase activity|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron differentiation|positive regulation of cell size|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|digestive tract morphogenesis|neuron development|positive regulation of oligodendrocyte differentiation|protein tetramerization|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of apoptotic signaling pathway|",p53 binding|DNA binding|chromatin binding|damaged DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein kinase binding|identical protein binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,0.2,0.00909,0,0,0,0.903,0,0,-0.9,2
ENSMUSG00000034881,TBXA2R,thromboxane A2 receptor,acrosomal vesicle|intracellular|plasma membrane|membrane|integral component of membrane|,inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|regulation of vasoconstriction|second-messenger-mediated signaling|response to lipopolysaccharide|positive regulation of angiogenesis|positive regulation of blood pressure|positive regulation of vasoconstriction|positive regulation of smooth muscle contraction|,signal transducer activity|G-protein coupled receptor activity|thromboxane receptor activity|thromboxane receptor activity|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.3,1.8
ENSMUSG00000056763,CSPP1,centrosome and spindle pole associated protein 1,spindle pole|spindle pole|cytoplasm|centrosome|spindle|spindle|cytoskeleton|microtubule|,positive regulation of cytokinesis|positive regulation of cell division|,protein binding|,10,0,0,10,0.3,0.368,0,0,0,0.903,0,0,-0.8,2
ENSMUSG00000024033,RSPH1,radial spoke head 1 homolog (Chlamydomonas),nucleus|chromosome|cytoplasm|cytosol|motile cilium|cell projection|,meiotic nuclear division|axoneme assembly|,None,10,0.8,2.16,10,0,0,0,0,0,0.903,0,0,-0.6,2
ENSMUSG00000043050,TNP2,transition protein 2,nucleosome|male germ cell nucleus|cell|nucleus|nucleus|chromosome|,multicellular organismal development|spermatogenesis|binding of sperm to zona pellucida|acrosome reaction|penetration of zona pellucida|cell differentiation|sperm motility|,DNA binding|zinc ion binding|metal ion binding|,10,-0.1,0.0209,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000009406,ELK1,"ELK1, member of ETS oncogene family",nucleus|nucleus|cytoplasm|mitochondrion|dendrite|neuronal cell body|axon terminus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|response to light stimulus|cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|cellular response to lipid|cellular response to gamma radiation|positive regulation of neuron death|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|core promoter binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.1,0.0102,10,-0.1,0.0969,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000033671,CEP350,centrosomal protein 350,nucleus|cytoplasm|centrosome|membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.6
ENSMUSG00000001403,UBE2C,ubiquitin-conjugating enzyme E2C,anaphase-promoting complex|,ubiquitin-dependent protein catabolic process|cell cycle|mitotic nuclear division|cyclin catabolic process|exit from mitosis|free ubiquitin chain polymerization|protein ubiquitination|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|positive regulation of exit from mitosis|cell division|protein K48-linked ubiquitination|protein K11-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,-1,1.71,10,0,0,0,0,0,0.903,0,0,-2,0.9
ENSMUSG00000027314,DLL4,delta-like 4 (Drosophila),integral component of plasma membrane|membrane|integral component of membrane|,negative regulation of transcription from RNA polymerase II promoter|angiogenesis|patterning of blood vessels|blood vessel remodeling|cardiac ventricle morphogenesis|cardiac atrium morphogenesis|ventricular trabecula myocardium morphogenesis|pericardium morphogenesis|cell communication|Notch signaling pathway|multicellular organismal development|nervous system development|visual perception|negative regulation of cell proliferation|negative regulation of endothelial cell migration|cell differentiation|dorsal aorta morphogenesis|cellular response to vascular endothelial growth factor stimulus|negative regulation of blood vessel endothelial cell migration|cellular response to fibroblast growth factor stimulus|regulation of neurogenesis|response to stimulus|ventral spinal cord interneuron fate commitment|regulation of neural retina development|Notch signaling involved in heart development|blood vessel lumenization|negative regulation of cell migration involved in sprouting angiogenesis|positive regulation of neural precursor cell proliferation|,Notch binding|Notch binding|calcium ion binding|protein binding|,10,0.3,0.484,10,0,0,0,0,0,0.903,0,0,-1.7,1.4
ENSMUSG00000027868,TBX15,T-box 15,nucleus|Tle3-Aes complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II transcription corepressor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|protein heterodimerization activity|,10,-0.1,0.0138,10,0,0,0,0,0,0.903,0,0,-2,1
ENSMUSG00000038304,CD160,CD160 antigen,plasma membrane|membrane|anchored component of membrane|anchored component of plasma membrane|,signal transduction|defense response to Gram-negative bacterium|,receptor binding|MHC class I receptor activity|,10,0,0,10,0.4,0.498,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000030713,KLK7,"kallikrein related-peptidase 7 (chymotryptic, stratum corneum)",extracellular region|epidermal lamellar body|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.00804,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000018604,TBX3,T-box 3,nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|skeletal system development|blood vessel development|in utero embryonic development|heart looping|heart morphogenesis|outflow tract morphogenesis|atrioventricular bundle cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell aging|cell aging|positive regulation of cell proliferation|anterior/posterior axis specification, embryo|organ morphogenesis|specification of organ position|stem cell maintenance|limbic system development|male genitalia development|female genitalia development|negative regulation of epithelial cell differentiation|mammary gland development|mammary gland development|luteinizing hormone secretion|limb morphogenesis|embryonic forelimb morphogenesis|forelimb morphogenesis|regulation of cell proliferation|embryonic digit morphogenesis|negative regulation of apoptotic process|negative regulation of myoblast differentiation|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|follicle-stimulating hormone secretion|mesoderm morphogenesis|cardiac muscle cell differentiation|palate development|ventricular septum morphogenesis|branching involved in mammary gland duct morphogenesis|mammary placode formation|mammary placode formation|cardiac muscle cell fate commitment|sinoatrial node cell development|cellular senescence|positive regulation of stem cell proliferation|",RNA polymerase II transcription factor binding|RNA polymerase II activating transcription factor binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.8,0.331,10,0.4,0.265,0,0,0,0.903,0,0,-1.8,1.4
ENSMUSG00000024669,CD5,CD5 antigen,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|fully spanning plasma membrane|,T cell costimulation|apoptotic signaling pathway|,glycoprotein binding|scavenger receptor activity|protein binding|,10,0,0,10,-0.2,0.233,0,0,0,0.903,0,0,-1.8,1.2
ENSMUSG00000006345,GGT1,gamma-glutamyltransferase 1,extracellular space|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|membrane-bounded vesicle|extracellular vesicular exosome|,regulation of immune system process|proteolysis|glutamate metabolic process|glutathione metabolic process|glutathione biosynthetic process|glutathione catabolic process|spermatogenesis|cysteine biosynthetic process|leukotriene biosynthetic process|peptide modification|zymogen activation|regulation of inflammatory response|lung connective tissue development|cellular response to mechanical stimulus|,"gamma-glutamyltransferase activity|gamma-glutamyltransferase activity|peptidase activity|transferase activity|transferase activity, transferring acyl groups|hydrolase activity|glutathione hydrolase activity|",10,0.2,0.402,10,-0.1,0.167,0,0,0,0.903,0,0,-1.4,1.6
ENSMUSG00000053719,KLK1B26,kallikrein 1-related petidase b26,extracellular space|nucleus|,brain renin-angiotensin system|proteolysis|zymogen activation|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.1,0.164,0,0,0,0.903,0,0,-1.7,1.2
ENSMUSG00000037169,MYCN,"v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)",nucleus|nucleus|,"cartilage condensation|positive regulation of mesenchymal cell proliferation|regulation of transcription, DNA-templated|positive regulation of cell proliferation|positive regulation of cell death|lung development|embryonic digit morphogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|negative regulation of astrocyte differentiation|branching morphogenesis of an epithelial tube|negative regulation of reactive oxygen species metabolic process|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein dimerization activity|,10,-0.1,0.0978,10,0.1,0.017,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000022540,ROGDI,rogdi homolog (Drosophila),intracellular|nucleus|,positive regulation of cell proliferation|hemopoiesis|,molecular_function|,10,0.2,0.353,10,0,0,0,0,0,0.903,0,0,-1.1,1.8
ENSMUSG00000026175,VIL1,villin 1,ruffle|cytoplasm|cytoskeleton|microvillus|microvillus|brush border|lamellipodium|lamellipodium|filopodium|filopodium|actin filament bundle|filopodium tip|cell projection|extracellular vesicular exosome|,apoptotic process|cytoskeleton organization|epidermal growth factor receptor signaling pathway|regulation of cell shape|response to bacterium|positive regulation of epithelial cell migration|actin filament polymerization|actin filament depolymerization|positive regulation of cell migration|positive regulation of actin filament bundle assembly|cellular response to hepatocyte growth factor stimulus|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|actin filament severing|regulation of actin nucleation|actin filament capping|cytoplasmic actin-based contraction involved in cell motility|regulation of wound healing|cellular response to epidermal growth factor stimulus|regulation of lamellipodium morphogenesis|,"actin binding|calcium ion binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|lysophosphatidic acid binding|identical protein binding|protein homodimerization activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|metal ion binding|actin filament binding|",10,0.1,0.0892,10,0.7,0.153,0,0,0,0.903,0,0,-1,1.9
ENSMUSG00000096914,GALNTL6,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0,0,10,-0.1,0.357,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000021417,ECI2,enoyl-Coenzyme A delta isomerase 2,nucleus|mitochondrion|mitochondrion|peroxisome|peroxisome|peroxisomal matrix|peroxisomal matrix|membrane|intracellular membrane-bounded organelle|,fatty acid beta-oxidation|metabolic process|fatty acid catabolic process|fatty acid catabolic process|,"fatty-acyl-CoA binding|catalytic activity|dodecenoyl-CoA delta-isomerase activity|dodecenoyl-CoA delta-isomerase activity|receptor binding|isomerase activity|intramolecular oxidoreductase activity, transposing C=C bonds|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1.2,1.8
ENSMUSG00000028687,MUTYH,mutY homolog (E. coli),nucleus|mitochondrion|mitochondrion|,DNA repair|base-excision repair|cellular response to DNA damage stimulus|response to oxidative stress|metabolic process|,"purine-specific mismatch base pair DNA N-glycosylase activity|catalytic activity|uracil DNA N-glycosylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|DNA N-glycosylase activity|MutSalpha complex binding|DNA-3-methylbase glycosylase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1,2
ENSMUSG00000056536,PIGN,"phosphatidylinositol glycan anchor biosynthesis, class N",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|metabolic process|,"catalytic activity|transferase activity|phosphotransferase activity, for other substituted phosphate groups|Kdo transferase activity|",9,-0.7,1.18,9,0,0,0,0,0,0.903,0,0,-2,1
ENSMUSG00000023868,PDE10A,phosphodiesterase 10A,cytoplasm|membrane|neuronal cell body|perikaryon|,cAMP catabolic process|signal transduction|metabolic process|regulation of protein kinase A signaling|regulation of cAMP-mediated signaling|cGMP catabolic process|,"nucleotide binding|catalytic activity|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|drug binding|hydrolase activity|cAMP binding|cGMP binding|metal ion binding|3',5'-cyclic-GMP phosphodiesterase activity|",10,0,0,10,0,0,0,0,0,0.903,0,0,-1.5,1.5
ENSMUSG00000027070,LRP2,low density lipoprotein receptor-related protein 2,extracellular space|cytoplasm|lysosomal membrane|endosome|endosome|endoplasmic reticulum|Golgi apparatus|brush border|brush border|coated pit|membrane|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|endocytic vesicle|brush border membrane|brush border membrane|protein complex|receptor complex|membrane raft|apical part of cell|extracellular vesicular exosome|,vitamin metabolic process|endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|cell proliferation|response to X-ray|endosomal transport|hemoglobin import|forebrain development|lipoprotein transport|transcytosis|hormone secretion|,receptor activity|receptor activity|calcium ion binding|protein binding|SH3 domain binding|PDZ domain binding|hemoglobin binding|protein complex binding|lipoprotein transporter activity|metal ion binding|low-density lipoprotein particle receptor binding|,10,0,0,10,-0.1,0.133,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000018821,AVPI1,arginine vasopressin-induced 1,cellular_component|,activation of MAPK activity|cell cycle|,molecular_function|,10,0.2,0.247,10,0,0,0,0,0,0.903,0,0,-1.3,1.7
ENSMUSG00000004231,PAX2,paired box 2,intracellular|nucleus|nucleus|transcription factor complex|lysosome|microtubule organizing center|protein-DNA complex|centriolar satellite|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|urogenital system development|urogenital system development|metanephros development|metanephros development|ureteric bud development|branching involved in ureteric bud morphogenesis|branching involved in ureteric bud morphogenesis|cell fate determination|kidney development|kidney development|mesonephros development|neural tube closure|optic cup morphogenesis involved in camera-type eye development|retinal pigment epithelium development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|mesodermal cell fate specification|positive regulation of cell proliferation|glial cell differentiation|optic nerve development|optic nerve morphogenesis|optic nerve structural organization|vestibulocochlear nerve formation|cell differentiation|regulation of metanephros size|regulation of metanephros size|ureter maturation|inner ear morphogenesis|inner ear morphogenesis|regulation of apoptotic process|camera-type eye development|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of programmed cell death|negative regulation of programmed cell death|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|protein kinase B signaling|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of cytolysis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|organ development|pronephros development|brain morphogenesis|stem cell differentiation|positive regulation of epithelial cell proliferation|oxidation-reduction process|mesenchymal to epithelial transition|paramesonephric duct development|optic chiasma development|cellular response to glucose stimulus|renal system development|metanephric mesenchyme development|positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|metanephric mesenchymal cell differentiation|mesonephric tubule development|mesonephric tubule formation|mesonephric duct development|nephric duct formation|ureter development|metanephric collecting duct development|metanephric distal convoluted tubule development|metanephric nephron tubule formation|positive regulation of metanephric glomerulus development|negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis|regulation of metanephric nephron tubule epithelial cell differentiation|reactive oxygen species metabolic process|cochlea development|cochlea morphogenesis|cochlea morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|negative regulation of mesenchymal cell apoptotic process involved in metanephros development|negative regulation of apoptotic process involved in metanephric collecting duct development|negative regulation of apoptotic process involved in metanephric nephron tubule development|negative regulation of reactive oxygen species metabolic process|positive regulation of metanephric DCT cell differentiation|positive regulation of optic nerve formation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|core promoter proximal region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|superoxide-generating NADPH oxidase activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|C2H2 zinc finger domain binding|,10,0,0,10,0,0,0,0,0,0.903,0,0,-1.7,1.4
ENSMUSG00000032087,DSCAML1,Down syndrome cell adhesion molecule like 1,extracellular space|plasma membrane|cell surface|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|homophilic cell adhesion|negative regulation of cell adhesion|nervous system development|brain development|calcium-independent cell-cell adhesion|embryonic skeletal system morphogenesis|dendrite self-avoidance|,protein homodimerization activity|,10,-0.2,0.563,10,0,0,0,0,0,0.903,0,0,-1.6,1.4
ENSMUSG00000021223,PAPLN,"papilin, proteoglycan-like sulfated glycoprotein",extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular matrix|,negative regulation of peptidase activity|,metalloendopeptidase activity|serine-type endopeptidase inhibitor activity|peptidase activity|metallopeptidase activity|zinc ion binding|peptidase inhibitor activity|,10,-0.2,0.261,10,0,0,0,0,0,0.903,0,0,-1.7,1.3
ENSMUSG00000033444,SPECC1L,sperm antigen with calponin homology and coiled-coil domains 1-like,cytoplasm|microtubule organizing center|cytoskeleton|gap junction|actin cytoskeleton|microtubule cytoskeleton|cell junction|filamentous actin|,negative regulation of microtubule depolymerization|cell cycle|cell adhesion|cell migration|actin cytoskeleton organization|negative regulation of actin filament depolymerization|cell division|face morphogenesis|,molecular_function|,10,0,0,10,-0.1,0.161,0,0,0,0.903,0,0,-1.5,1.4
ENSMUSG00000030287,ITPR2,"inositol 1,4,5-triphosphate receptor 2",cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|cell cortex|membrane|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|axon|sarcoplasmic reticulum membrane|myelin sheath|receptor complex|,response to hypoxia|transport|ion transport|calcium ion transport|inositol phosphate-mediated signaling|inositol phosphate-mediated signaling|transmembrane transport|calcium ion transmembrane transport|cellular response to cAMP|cellular response to ethanol|,"ion channel activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity|calcium channel activity|calcium ion binding|calcium-release channel activity|phosphatidylinositol binding|inositol 1,4,5 trisphosphate binding|",10,0,0,10,0.1,0.0707,0,0,0,0.903,0,0,-1.1,2
ENSMUSG00000059042,KLK1B9,kallikrein 1-related peptidase b9,nucleus|,proteolysis|zymogen activation|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.5,1.53,0,0,0,0.903,0,0,-1.7,1.5
ENSMUSG00000022391,RANGAP1,RAN GTPase activating protein 1,"chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|cytoskeleton|membrane|perinuclear region of cytoplasm|",signal transduction|negative regulation of protein export from nucleus|,GTPase activator activity|Ran GTPase activator activity|,4,0,0,5,-0.1,0.0818,0,0,0,0.903,0,0,-1.9,1.6
ENSMUSG00000003575,CRTC1,CREB regulated transcription coactivator 1,nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|memory|positive regulation of CREB transcription factor activity|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein homotetramerization|membrane hyperpolarization|",cAMP response element binding protein binding|,10,-0.3,0.0691,10,0,0,0,0,0,0.903,0,0,-1.8,1.1
ENSMUSG00000029173,SEPSECS,Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase,nucleus|cytoplasm|,selenocysteine incorporation|translation|selenocysteinyl-tRNA(Sec) biosynthetic process|,"tRNA binding|RNA binding|catalytic activity|protein binding|transferase activity|transferase activity, transferring selenium-containing groups|pyridoxal phosphate binding|",10,2.1,91.2,10,1.3,21.7,2,109,109,1.00E-05,1,1,1.4,2.5
ENSMUSG00000026856,DOLPP1,dolichyl pyrophosphate phosphatase 1,endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,protein N-linked glycosylation|lipid biosynthetic process|,catalytic activity|hydrolase activity|dolichyldiphosphatase activity|,9,2.2,54.2,9,1.2,25.3,1.8,75.6,75.6,1.00E-05,1,1,1.3,2.5
ENSMUSG00000048076,ARF1,ADP-ribosylation factor 1,intracellular|cytoplasm|Golgi apparatus|cytosol|plasma membrane|endomembrane system|membrane|sarcomere|cell junction|neuron projection|synapse|postsynaptic membrane|extracellular vesicular exosome|,regulation of receptor internalization|transport|cellular copper ion homeostasis|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|regulation of Arp2/3 complex-mediated actin nucleation|long term synaptic depression|dendritic spine organization|,nucleotide binding|protein binding|GTP binding|poly(A) RNA binding|,10,1.2,29.9,10,0.8,25.9,1.1,53.1,53.1,2.00E-05,1,1,0.8,1.7
ENSMUSG00000023067,CDKN1A,cyclin-dependent kinase inhibitor 1A (P21),cyclin-dependent protein kinase holoenzyme complex|cyclin-dependent protein kinase holoenzyme complex|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|PCNA-p21 complex|,"regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|G2/M transition of mitotic cell cycle|protein phosphorylation|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cell cycle|cell cycle arrest|cell cycle arrest|regulation of mitotic cell cycle|negative regulation of cell proliferation|negative regulation of cell proliferation|response to UV|negative regulation of gene expression|phosphorylation|negative regulation of cell growth|positive regulation of B cell proliferation|cellular response to extracellular stimulus|regulation of protein import into nucleus, translocation|negative regulation of phosphorylation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of apoptotic process|positive regulation of programmed cell death|negative regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of protein kinase activity|positive regulation of fibroblast proliferation|regulation of cell cycle|cellular response to ionizing radiation|mitotic cell cycle arrest|cellular senescence|regulation of DNA biosynthetic process|positive regulation of reactive oxygen species metabolic process|",protein kinase inhibitor activity|cyclin-dependent protein serine/threonine kinase inhibitor activity|protein binding|kinase activity|transferase activity|cyclin-dependent protein kinase activating kinase activity|cyclin binding|protein complex binding|metal ion binding|,10,0.8,19.2,10,1,33.6,0.9,51.9,51.9,2.00E-05,1,1,0.7,1.3
ENSMUSG00000031730,DHODH,dihydroorotate dehydrogenase,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|neuronal cell body|,'de novo' pyrimidine nucleobase biosynthetic process|pyrimidine nucleotide biosynthetic process|UMP biosynthetic process|positive regulation of apoptotic process|oxidation-reduction process|regulation of mitochondrial fission|,catalytic activity|dihydroorotate dehydrogenase activity|drug binding|FMN binding|oxidoreductase activity|ubiquinone binding|,8,1.3,28.6,8,0.7,22.5,1,47.3,47.3,4.00E-05,1,1,0.7,1.6
ENSMUSG00000005667,MTHFD2,"methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase",extracellular space|mitochondrion|,one-carbon metabolic process|metabolic process|folic acid-containing compound biosynthetic process|tetrahydrofolate metabolic process|oxidation-reduction process|,magnesium ion binding|catalytic activity|methenyltetrahydrofolate cyclohydrolase activity|methylenetetrahydrofolate dehydrogenase (NAD+) activity|methylenetetrahydrofolate dehydrogenase (NAD+) activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|oxidoreductase activity|hydrolase activity|phosphate ion binding|,9,2.3,41.4,9,1.4,7.96,2.3,47.1,47.1,4.00E-05,1,1,1.5,3.4
ENSMUSG00000018796,ACSL1,acyl-CoA synthetase long-chain family member 1,mitochondrion|mitochondrion|mitochondrial outer membrane|peroxisome|peroxisomal membrane|endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|triglyceride metabolic process|metabolic process|lipid biosynthetic process|response to organic substance|fatty acid transport|adiponectin-activated signaling pathway|xenobiotic catabolic process|long-chain fatty acid import|positive regulation of protein serine/threonine kinase activity|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|ATP binding|ligase activity|acetate-CoA ligase (ADP-forming) activity|,9,1,3.92,9,1.8,45.4,1.7,46.9,46.9,4.00E-05,1,1,1.2,2.9
ENSMUSG00000008475,ARPC5,"actin related protein 2/3 complex, subunit 5",cytoplasm|cytoskeleton|Arp2/3 protein complex|lamellipodium|cell projection|extracellular vesicular exosome|,regulation of actin filament polymerization|,actin binding|,10,0.7,24,10,0.8,21.5,0.7,44.9,44.9,6.00E-05,1,1,0.5,1.1
ENSMUSG00000025403,SHMT2,serine hydroxymethyltransferase 2 (mitochondrial),mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial intermembrane space|mitochondrial matrix|microtubule cytoskeleton|mitochondrial nucleoid|extracellular vesicular exosome|,glycine metabolic process|glycine biosynthetic process|L-serine biosynthetic process|one-carbon metabolic process|positive regulation of cell proliferation|glycine biosynthetic process from serine|methylation|protein homotetramerization|,chromatin binding|glycine hydroxymethyltransferase activity|methyltransferase activity|L-allo-threonine aldolase activity|amino acid binding|transferase activity|pyridoxal phosphate binding|identical protein binding|,9,1.5,26.8,9,1.2,18.9,1.4,44.7,44.7,6.00E-05,1,1,1,1.9
ENSMUSG00000026032,NDUFB3,NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|extracellular vesicular exosome|respiratory chain|,transport|biological_process|electron transport chain|oxidation-reduction process|,molecular_function|,10,2.4,37.5,10,0.7,11.3,0.8,42.7,42.7,0.00011,1,1,0.7,3
ENSMUSG00000007458,M6PR,"mannose-6-phosphate receptor, cation dependent",lytic vacuole|intracellular|cell|lysosome|endosome|late endosome|membrane|membrane|integral component of membrane|,transport|intracellular protein transport|mannose transport|,mannose binding|mannose transmembrane transporter activity|,10,1.2,20.4,9,1.3,22.1,1.3,42.1,42.1,0.00011,1,1,1,1.9
ENSMUSG00000021987,MTMR6,myotubularin related protein 6,nucleus|cytoplasm|,dephosphorylation|potassium ion transmembrane transport|,"protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|calcium-activated potassium channel activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,1.8,7.73,10,1,31.8,1.1,35.8,35.8,0.00023,1,1,0.7,2
ENSMUSG00000071014,NDUFB6,"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|mitochondrial membrane|respiratory chain|,transport|oxidation-reduction process|,None,9,1.1,17.5,9,1.6,20.6,1.5,35.2,35.2,0.00026,1,1,0.9,2.3
ENSMUSG00000029622,ARPC1B,"actin related protein 2/3 complex, subunit 1B",cytoplasm|cytoskeleton|Arp2/3 protein complex|extracellular vesicular exosome|,regulation of actin filament polymerization|,actin binding|,10,1,20.2,10,1,11.4,1,31.2,31.2,0.00051,1,1,0.6,1.4
ENSMUSG00000004266,PTPN6,"protein tyrosine phosphatase, non-receptor type 6",intracellular|nucleus|nucleolus|cytoplasm|cytoplasm|cell-cell junction|alpha-beta T cell receptor complex|extracellular vesicular exosome|,hematopoietic progenitor cell differentiation|negative regulation of humoral immune response mediated by circulating immunoglobulin|protein dephosphorylation|protein dephosphorylation|protein dephosphorylation|signal transduction|cell proliferation|positive regulation of cell proliferation|positive regulation of phosphatidylinositol 3-kinase signaling|dephosphorylation|peptidyl-tyrosine phosphorylation|cytokine-mediated signaling pathway|cell differentiation|platelet formation|abortive mitotic cell cycle|positive regulation of cell adhesion mediated by integrin|peptidyl-tyrosine dephosphorylation|intracellular signal transduction|megakaryocyte development|negative regulation of T cell proliferation|natural killer cell mediated cytotoxicity|negative regulation of MAP kinase activity|negative regulation of MAPK cascade|regulation of B cell differentiation|negative regulation of peptidyl-tyrosine phosphorylation|negative regulation of peptidyl-tyrosine phosphorylation|B cell receptor signaling pathway|negative regulation of B cell receptor signaling pathway|negative regulation of T cell receptor signaling pathway|regulation of release of sequestered calcium ion into cytosol|regulation of ERK1 and ERK2 cascade|platelet aggregation|regulation of G1/S transition of mitotic cell cycle|,phosphotyrosine binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|transmembrane receptor protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|SH3 domain binding|protein kinase binding|SH2 domain binding|natural killer cell lectin-like receptor binding|,10,-0.6,16.2,10,-0.8,15.5,-0.7,31.1,-31.1,0.00051,1,1,-1.1,-0.5
ENSMUSG00000014294,NDUFA2,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial respiratory chain complex I|membrane|mitochondrial membrane|respiratory chain|,transport|oxidation-reduction process|,NADH dehydrogenase (ubiquinone) activity|,9,1.2,15.9,8,1.6,16.6,1.4,30.8,30.8,0.00053,1,1,0.9,2.2
ENSMUSG00000026753,PPP6C,"protein phosphatase 6, catalytic subunit",cytoplasm|cytosol|,protein dephosphorylation|cell cycle|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,9,2.5,23.2,7,1,11.6,2.4,30.3,30.3,0.00056,1,1,0.8,4.3
ENSMUSG00000034424,GCSH,glycine cleavage system protein H (aminomethyl carrier),mitochondrion|mitochondrion|glycine cleavage complex|,glycine decarboxylation via glycine cleavage system|methylation|,aminomethyltransferase activity|enzyme binding|,10,0.9,11.9,10,1,18.8,0.9,30.2,30.2,0.00056,1,1,0.5,1.3
ENSMUSG00000027610,GSS,glutathione synthetase,extracellular vesicular exosome|,glutathione biosynthetic process|glutathione biosynthetic process|response to cadmium ion|,nucleotide binding|magnesium ion binding|glutathione synthase activity|glutathione synthase activity|ATP binding|glycine binding|ligase activity|peptide binding|protein homodimerization activity|glutathione binding|metal ion binding|,10,2,25.2,10,0.5,13.6,1.5,29.8,29.8,0.00059,1,1,0.4,2.7
ENSMUSG00000032388,SPG21,spastic paraplegia 21 homolog (human),nucleus|cytoplasm|cytosol|trans-Golgi network transport vesicle|,biological_process|,CD4 receptor binding|,10,1,25.8,10,0.4,6.08,0.9,28.7,28.7,0.00085,1,1,0.5,1.3
ENSMUSG00000035376,PTPLB,"protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|biological_process|,molecular_function|lyase activity|,10,0.8,12.2,10,1.5,17.4,1.4,28.1,28.1,0.00096,1,1,0.4,2
ENSMUSG00000056305,USP39,ubiquitin specific peptidase 39,nucleus|spliceosomal complex|,mRNA processing|ubiquitin-dependent protein catabolic process|cell cycle|RNA splicing|cell division|,zinc ion binding|ubiquitinyl hydrolase activity|metal ion binding|,8,1.2,14.4,7,1,13.2,1.1,27.1,27.1,0.00126,0,1,0.7,1.7
ENSMUSG00000022414,TAB1,TGF-beta activated kinase 1/MAP3K7 binding protein 1,nucleus|cytoplasm|protein complex|,activation of MAPKKK activity|in utero embryonic development|heart morphogenesis|transforming growth factor beta receptor signaling pathway|lung development|positive regulation of MAP kinase activity|,catalytic activity|protein binding|kinase activator activity|protein complex binding|mitogen-activated protein kinase p38 binding|,10,-1.3,19.2,10,-0.6,9.13,-1,26.3,-26.3,0.00161,0,1,-1.8,-0.5
ENSMUSG00000024539,PTPN2,"protein tyrosine phosphatase, non-receptor type 2",nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|plasma membrane|membrane|,protein dephosphorylation|negative regulation of cell proliferation|insulin receptor signaling pathway|negative regulation of tumor necrosis factor-mediated signaling pathway|negative regulation of lipid storage|dephosphorylation|B cell differentiation|T cell differentiation|erythrocyte differentiation|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of tyrosine phosphorylation of Stat6 protein|negative regulation of tyrosine phosphorylation of Stat6 protein|glucose homeostasis|negative regulation of macrophage differentiation|positive regulation of gluconeogenesis|negative regulation of insulin receptor signaling pathway|negative regulation of inflammatory response|negative regulation of T cell receptor signaling pathway|negative regulation of chemotaxis|negative regulation of interferon-gamma-mediated signaling pathway|negative regulation of type I interferon-mediated signaling pathway|negative regulation of type I interferon-mediated signaling pathway|negative regulation of interleukin-6-mediated signaling pathway|negative regulation of interleukin-6-mediated signaling pathway|negative regulation of ERK1 and ERK2 cascade|regulation of hepatocyte growth factor receptor signaling pathway|negative regulation of interleukin-2-mediated signaling pathway|negative regulation of interleukin-2-mediated signaling pathway|negative regulation of prolactin signaling pathway|negative regulation of interleukin-4-mediated signaling pathway|negative regulation of interleukin-4-mediated signaling pathway|negative regulation of macrophage colony-stimulating factor signaling pathway|negative regulation of positive thymic T cell selection|negative regulation of platelet-derived growth factor receptor-beta signaling pathway|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|non-membrane spanning protein tyrosine phosphatase activity|integrin binding|protein binding|hydrolase activity|phosphatase activity|protein kinase binding|syntaxin binding|receptor tyrosine kinase binding|,10,-0.6,6.05,10,-1.1,21.9,-0.8,26.2,-26.2,0.00163,0,1,-1.5,-0.6
ENSMUSG00000031537,IKBKB,inhibitor of kappaB kinase beta,nucleus|cytoplasm|cytoplasm|cytosol|IkappaB kinase complex|cytoplasmic side of plasma membrane|membrane|CD40 receptor complex|intracellular membrane-bounded organelle|,B cell homeostasis|protein phosphorylation|protein phosphorylation|I-kappaB phosphorylation|I-kappaB phosphorylation|positive regulation of cell proliferation|positive regulation of sodium ion transport|phosphorylation|signal transduction by phosphorylation|neuron projection development|serine phosphorylation of STAT protein|positive regulation of transcription from RNA polymerase II promoter|positive regulation of NF-kappaB transcription factor activity|cellular response to tumor necrosis factor|positive regulation of neuron death|positive regulation of cation channel activity|,"nucleotide binding|protein kinase activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|protein binding|ATP binding|IkappaB kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein homodimerization activity|protein heterodimerization activity|scaffold protein binding|",10,-0.5,4.98,10,-0.8,21.9,-0.7,26.1,-26.1,0.0017,0,1,-1.2,-0.5
ENSMUSG00000023143,NAGPA,N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase,Golgi apparatus|membrane|integral component of membrane|,None,N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity|hydrolase activity|,10,0.1,0.0246,10,1.6,27.7,0.4,25.1,25.1,0.00228,0,1,0.3,2.6
ENSMUSG00000025130,P4HB,"prolyl 4-hydroxylase, beta polypeptide",endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|plasma membrane|membrane|procollagen-proline 4-dioxygenase complex|extracellular vesicular exosome|,protein folding|protein folding|peptidyl-proline hydroxylation to 4-hydroxy-L-proline|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|cell redox homeostasis|cellular response to hypoxia|regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,protein disulfide isomerase activity|protein disulfide isomerase activity|procollagen-proline 4-dioxygenase activity|isomerase activity|enzyme binding|peptidyl-proline 4-dioxygenase activity|poly(A) RNA binding|protein heterodimerization activity|,10,1,22.4,10,0.5,4.31,0.8,25.1,25.1,0.00228,0,1,0.5,1.4
ENSMUSG00000050697,PRKAA1,"protein kinase, AMP-activated, alpha 1 catalytic subunit",nucleus|nucleus|cytoplasm|cytoplasm|apical plasma membrane|AMP-activated protein kinase complex|protein complex|,"activation of MAPK activity|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|steroid biosynthetic process|cholesterol biosynthetic process|autophagy|steroid metabolic process|cholesterol metabolic process|positive regulation of cell proliferation|lipid biosynthetic process|response to UV|cold acclimation|response to gamma radiation|positive regulation of autophagy|positive regulation of gene expression|response to activity|Wnt signaling pathway|sterol biosynthetic process|phosphorylation|chromatin modification|fatty acid oxidation|response to caffeine|cellular response to nutrient levels|negative regulation of TOR signaling|histone-serine phosphorylation|cellular response to glucose starvation|response to hydrogen peroxide|glucose homeostasis|regulation of circadian rhythm|negative regulation of apoptotic process|positive regulation of glycolytic process|rhythmic process|negative regulation of lipid catabolic process|protein heterooligomerization|fatty acid homeostasis|regulation of vesicle-mediated transport|response to camptothecin|regulation of energy homeostasis|negative regulation of glucose import in response to insulin stimulus|","nucleotide binding|chromatin binding|protein kinase activity|protein serine/threonine kinase activity|AMP-activated protein kinase activity|AMP-activated protein kinase activity|AMP-activated protein kinase activity|protein binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|kinase binding|histone serine kinase activity|metal ion binding|[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity|tau-protein kinase activity|[acetyl-CoA carboxylase] kinase activity|",10,-0.8,11,10,-0.7,14.6,-0.8,25.1,-25.1,0.00228,0,1,-1.2,-0.5
ENSMUSG00000049299,TRAPPC1,trafficking protein particle complex 1,endoplasmic reticulum|Golgi apparatus|cis-Golgi network|TRAPP complex|,transport|ER to Golgi vesicle-mediated transport|biological_process|vesicle-mediated transport|,protein binding|,7,1.4,20.6,7,0.6,7.38,1.3,24.9,24.9,0.00242,0,1,0.8,1.9
ENSMUSG00000026127,IMP4,"IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)",nucleus|nucleolus|nucleolus|ribonucleoprotein complex|,rRNA processing|ribosome biogenesis|,RNA binding|snoRNP binding|,8,-1.8,23.8,7,-0.4,4.83,-0.5,24.9,-24.9,0.00242,0,1,-2.8,-0.4
ENSMUSG00000040048,NDUFB10,"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|extracellular vesicular exosome|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,9,1.6,20.5,10,0.9,6.62,1.6,24.3,24.3,0.00282,0,1,0.9,2.3
ENSMUSG00000007564,PPP2R1A,"protein phosphatase 2, regulatory subunit A, alpha","protein phosphatase type 2A complex|protein phosphatase type 2A complex|chromosome, centromeric region|chromosome|cytoplasm|cytosol|",chromosome segregation|peptidyl-serine dephosphorylation|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,antigen binding|protein serine/threonine phosphatase activity|protein binding|protein heterodimerization activity|,8,0.9,17.3,5,0.6,7.95,0.8,24.1,24.1,0.00294,0,1,0.5,1.6
ENSMUSG00000036737,OXSR1,oxidative-stress responsive 1,intracellular|cytoplasm|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|response to oxidative stress|phosphorylation|peptidyl-threonine phosphorylation|signal transduction by phosphorylation|intracellular signal transduction|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",9,0.8,9.13,10,0.7,15.2,0.7,23.9,23.9,0.00307,0,1,0.4,1.2
ENSMUSG00000001783,RTCB,"RNA 2',3'-cyclic phosphate and 5'-OH ligase",cytoplasm|tRNA-splicing ligase complex|,"in utero embryonic development|placenta development|tRNA splicing, via endonucleolytic cleavage and ligation|RNA processing|tRNA processing|",nucleotide binding|RNA ligase (ATP) activity|ATP binding|RNA ligase activity|ligase activity|vinculin binding|poly(A) RNA binding|metal ion binding|,8,1.6,6.91,8,0.8,19.8,0.9,23.9,23.9,0.00307,0,1,0.6,2
ENSMUSG00000031485,PROSC,proline synthetase co-transcribed,intracellular|mitochondrion|extracellular vesicular exosome|,alpha-amino acid metabolic process|,pyridoxal phosphate binding|,10,1.3,26.6,9,0.1,0.113,1.3,23.7,23.7,0.00329,0,1,0.8,2.3
ENSMUSG00000020368,CANX,calnexin,cell|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|smooth endoplasmic reticulum|rough endoplasmic reticulum|ribosome|membrane|membrane|integral component of membrane|axon|dendrite cytoplasm|neuronal cell body|dendritic spine|protein complex|ER-mitochondrion membrane contact site|extracellular vesicular exosome|,protein folding|synaptic vesicle endocytosis|chaperone-mediated protein folding|clathrin-mediated endocytosis|,glycoprotein binding|calcium ion binding|protein binding|apolipoprotein binding|ionotropic glutamate receptor binding|poly(A) RNA binding|metal ion binding|unfolded protein binding|,10,1.1,11,10,0.5,13.7,0.6,23,23,0.00389,0,0,0.4,1.4
ENSMUSG00000017404,RPL19,ribosomal protein L19,intracellular|nucleolus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,4,1.8,17,4,0.7,8.7,1.7,22.7,22.7,0.00427,0,0,0.8,2.7
ENSMUSG00000075703,EPT1,ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific),cellular_component|membrane|integral component of membrane|,lipid metabolic process|biological_process|phospholipid biosynthetic process|,"molecular_function|ethanolaminephosphotransferase activity|transferase activity|phosphotransferase activity, for other substituted phosphate groups|metal ion binding|",10,0.8,11.1,10,0.6,11.9,0.7,22.1,22.1,0.00504,0,0,0.4,1.2
ENSMUSG00000028530,JAK1,Janus kinase 1,intracellular|nucleus|cytoplasm|cytoskeleton|membrane|,protein phosphorylation|enzyme linked receptor protein signaling pathway|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cytokine-mediated signaling pathway|intracellular signal transduction|interleukin-2-mediated signaling pathway|response to antibiotic|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|growth hormone receptor binding|growth hormone receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|CCR5 chemokine receptor binding|",10,0.7,10.9,10,0.5,11.8,0.6,22.1,22.1,0.00504,0,0,0.4,1
ENSMUSG00000028847,TRAPPC3,trafficking protein particle complex 3,Golgi membrane|endoplasmic reticulum|Golgi apparatus|cytosol|TRAPP complex|,transport|ER to Golgi vesicle-mediated transport|vesicle-mediated transport|,protein binding|,7,1.5,19.1,6,0.5,7.46,1.4,22,22,0.00529,0,0,0.6,2.2
ENSMUSG00000037902,SIRPA,signal-regulatory protein alpha,integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,"hematopoietic progenitor cell differentiation|phagocytosis, recognition|phagocytosis, engulfment|cellular component movement|cytoskeleton organization|actin filament organization|cell-matrix adhesion|cell migration|positive regulation of phagocytosis|",protein binding|SH3 domain binding|protein phosphorylated amino acid binding|,10,0.5,5.58,10,0.6,16.5,0.6,21.6,21.6,0.00593,0,0,0.4,1
ENSMUSG00000030282,CMAS,cytidine monophospho-N-acetylneuraminic acid synthetase,nucleus|nucleus|membrane|,CMP-N-acetylneuraminate biosynthetic process|lipopolysaccharide biosynthetic process|,N-acylneuraminate cytidylyltransferase activity|transferase activity|nucleotidyltransferase activity|,9,1.3,18.4,8,0.6,5.87,1.1,21.5,21.5,0.00606,0,0,0.6,2
ENSMUSG00000074698,CSNK2A1,"casein kinase 2, alpha 1 polypeptide",nucleus|protein kinase CK2 complex|Sin3 complex|NuRD complex|PcG protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|apoptotic process|cell cycle|positive regulation of cell proliferation|Wnt signaling pathway|phosphorylation|positive regulation of Wnt signaling pathway|positive regulation of cell growth|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of protein catabolic process|protein autophosphorylation|rhythmic process|regulation of catalytic activity|mitotic spindle checkpoint|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|beta-catenin binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase regulator activity|protein N-terminus binding|",10,-0.9,12.7,10,-1,8.78,-1,21,-21,0.007,0,0,-1.5,-0.6
ENSMUSG00000000088,COX5A,cytochrome c oxidase subunit Va,mitochondrion|mitochondrial inner membrane|membrane|extracellular vesicular exosome|,oxidation-reduction process|hydrogen ion transmembrane transport|,cytochrome-c oxidase activity|metal ion binding|,10,1.8,21,10,0.6,3.63,1.8,20.9,20.9,0.00721,0,0,1,2.7
ENSMUSG00000034663,BMP2K,BMP2 inducible kinase,nucleus|nucleus|,protein phosphorylation|phosphorylation|regulation of bone mineralization|regulation of catalytic activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphatase regulator activity|",10,0.2,0.632,10,-1.9,22.7,-1.8,20.9,-20.9,0.00721,0,0,-3,-1.2
ENSMUSG00000071866,PPIA,peptidylprolyl isomerase A,extracellular space|nucleus|cytosol|membrane|extracellular vesicular exosome|,protein peptidyl-prolyl isomerization|neuron differentiation|lipid particle organization|regulation of viral genome replication|positive regulation of viral genome replication|positive regulation of protein secretion|,peptidyl-prolyl cis-trans isomerase activity|protein binding|cyclosporin A binding|poly(A) RNA binding|,8,0.7,3.33,7,0.8,17.9,0.8,20.8,20.8,0.00741,0,0,0.5,1.5
ENSMUSG00000060288,PPIH,peptidyl prolyl isomerase H,nucleus|spliceosomal complex|cytoplasm|nuclear speck|U4/U6 x U5 tri-snRNP complex|U4/U6 snRNP|,protein peptidyl-prolyl isomerization|mRNA processing|protein folding|RNA splicing|positive regulation of viral genome replication|,peptidyl-prolyl cis-trans isomerase activity|isomerase activity|ribonucleoprotein complex binding|,7,2.7,23.7,7,0.2,0.917,2.7,20.8,20.8,0.00741,0,0,-2.5,5
ENSMUSG00000031562,DCTD,dCMP deaminase,extracellular vesicular exosome|,pyrimidine nucleotide metabolic process|biological_process|metabolic process|nucleotide biosynthetic process|,catalytic activity|dCMP deaminase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.8,17.6,10,0.4,5.66,0.8,20.5,20.5,0.00813,0,0,0.4,1.3
ENSMUSG00000026779,MASTL,microtubule associated serine/threonine kinase-like,nucleus|cytoplasm|centrosome|cytoskeleton|cleavage furrow|,G2/M transition of mitotic cell cycle|protein phosphorylation|cell cycle|mitotic nuclear division|phosphorylation|negative regulation of protein phosphatase type 2A activity|cell division|regulation of cell cycle|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,1,19.3,7,0.5,2.41,0.9,20.3,20.3,0.00852,0,0,0.5,1.6
ENSMUSG00000002379,NDUFA11,NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,0.7,15.9,10,0.6,4.99,0.7,20.2,20.2,0.00878,0,0,0.5,1.3
ENSMUSG00000042096,DAO,D-amino acid oxidase,mitochondrial outer membrane|peroxisome|peroxisomal membrane|cytosol|,leucine metabolic process|proline catabolic process|D-serine catabolic process|dopamine biosynthetic process|oxidation-reduction process|D-alanine catabolic process|D-alanine catabolic process|D-serine metabolic process|,"D-amino-acid oxidase activity|D-amino-acid oxidase activity|receptor binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor|protein dimerization activity|cofactor binding|cofactor binding|FAD binding|",9,-2.1,22.7,9,-0.3,1.1,-2.1,19.8,-19.8,0.00985,0,0,-4,-1.1
ENSMUSG00000008859,RALA,v-ral simian leukemia viral oncogene homolog A (ras related),plasma membrane|cell surface|membrane|endocytic vesicle|cleavage furrow|extracellular vesicular exosome|,cytokinesis|GTP catabolic process|exocytosis|cell cycle|signal transduction|small GTPase mediated signal transduction|Ras protein signal transduction|regulation of exocytosis|regulation of exocytosis|actin cytoskeleton reorganization|cell division|positive regulation of filopodium assembly|membrane raft localization|membrane raft localization|,nucleotide binding|GTPase activity|protein binding|GTP binding|Edg-2 lysophosphatidic acid receptor binding|,10,-2.2,22.1,10,-0.2,1.4,-2.2,19.4,-19.4,0.0111,0,0,-4,-1.3
ENSMUSG00000069631,STRADA,STE20-related kinase adaptor alpha,nucleus|cytoplasm|protein complex|,protein phosphorylation|protein export from nucleus|cell cycle|activation of protein kinase activity|activation of protein kinase activity|protein heterooligomerization|,"protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|transferase activity, transferring phosphorus-containing groups|kinase binding|protein kinase activator activity|",10,-1.3,15.5,10,-0.5,8.29,-0.8,19.3,-19.3,0.0116,0,0,-1.7,-0.3
ENSMUSG00000057963,ITPK1,"inositol 1,3,4-triphosphate 5/6 kinase",intracellular|,phosphorylation|inositol trisphosphate metabolic process|,"nucleotide binding|magnesium ion binding|ATP binding|kinase activity|transferase activity|hydrolase activity|isomerase activity|metal ion binding|inositol tetrakisphosphate 1-kinase activity|inositol-1,3,4-trisphosphate 6-kinase activity|inositol-1,3,4-trisphosphate 5-kinase activity|",10,-0.8,3.33,10,-0.8,16,-0.8,19,-19,0.0131,0,0,-1.4,-0.4
ENSMUSG00000029063,NADK,NAD kinase,cytosol|,NADP biosynthetic process|metabolic process|phosphorylation|NAD metabolic process|,nucleotide binding|NAD+ kinase activity|NAD+ kinase activity|ATP binding|kinase activity|transferase activity|metal ion binding|,9,1.8,7.72,9,1.3,12.8,1.5,18.5,18.5,0.0153,0,0,0.8,2.5
ENSMUSG00000005813,METAP1,methionyl aminopeptidase 1,cellular_component|cytoplasm|,proteolysis|,aminopeptidase activity|peptidase activity|metalloexopeptidase activity|hydrolase activity|metal ion binding|,10,0.7,9.21,10,1.2,11.8,0.8,18.4,18.4,0.0157,0,0,0.5,1.5
ENSMUSG00000002588,PON1,paraoxonase 1,extracellular region|extracellular space|high-density lipoprotein particle|spherical high-density lipoprotein particle|intracellular membrane-bounded organelle|extracellular vesicular exosome|blood microparticle|,blood circulation|cholesterol metabolic process|cholesterol metabolic process|response to toxic substance|positive regulation of cholesterol efflux|dephosphorylation|aromatic compound catabolic process|positive regulation of transporter activity|carboxylic acid catabolic process|organophosphate catabolic process|phosphatidylcholine metabolic process|positive regulation of binding|response to fluoride|,aryldialkylphosphatase activity|arylesterase activity|arylesterase activity|calcium ion binding|phospholipid binding|high-density lipoprotein particle binding|hydrolase activity|protein homodimerization activity|metal ion binding|,10,2.2,22,10,0,0,2.2,18.4,18.4,0.0157,0,0,1.6,4
ENSMUSG00000029199,LIAS,lipoic acid synthetase,mitochondrion|,neural tube closure|inflammatory response|response to oxidative stress|lipoate biosynthetic process|response to lipopolysaccharide|,"catalytic activity|transferase activity|lipoate synthase activity|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",7,1.2,16,8,0.8,3.13,1,18.2,18.2,0.0164,0,0,0.7,1.8
ENSMUSG00000042349,IKBKE,inhibitor of kappaB kinase epsilon,nucleus|cytoplasm|PML body|,protein phosphorylation|cellular response to DNA damage stimulus|I-kappaB phosphorylation|intrinsic apoptotic signaling pathway in response to DNA damage|phosphorylation|signal transduction by phosphorylation|NIK/NF-kappaB signaling|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|protein binding|ATP binding|IkappaB kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.401,10,-1.6,20.9,-1.5,18.1,-18.1,0.0168,0,0,-3,-0.4
ENSMUSG00000032308,ULK3,unc-51-like kinase 3,pre-autophagosomal structure|cytoplasm|cytosol|membrane|Atg1p signaling complex|,autophagic vacuole assembly|protein phosphorylation|autophagy|regulation of autophagy|phosphorylation|negative regulation of smoothened signaling pathway|positive regulation of smoothened signaling pathway|protein autophosphorylation|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-1.7,18.1,10,-0.5,3.02,-0.5,17.7,-17.7,0.018,0,0,-2.7,-0.3
ENSMUSG00000014361,MERTK,c-mer proto-oncogene tyrosine kinase,photoreceptor outer segment|extracellular space|intracellular|cell|cytoplasm|membrane|integral component of membrane|rhabdomere|,natural killer cell differentiation|protein phosphorylation|phagocytosis|spermatogenesis|phosphorylation|platelet activation|secretion by cell|substrate adhesion-dependent cell spreading|apoptotic cell clearance|apoptotic cell clearance|protein kinase B signaling|positive regulation of phagocytosis|negative regulation of lymphocyte activation|retina development in camera-type eye|vagina development|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.5,4.88,10,0.5,13.1,0.5,17.6,17.6,0.0182,0,0,0.3,0.9
ENSMUSG00000029062,CDK11B,cyclin-dependent kinase 11B,nucleus|nucleus|cytoplasm|,blastocyst development|protein phosphorylation|cell cycle|regulation of mitosis|phosphorylation|regulation of mRNA processing|negative regulation of apoptotic signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-1.6,18.1,9,-0.3,1.26,-0.4,17.5,-17.5,0.0185,0,0,-2.7,-0.3
ENSMUSG00000028882,PPP1R8,"protein phosphatase 1, regulatory (inhibitor) subunit 8",nucleus|spliceosomal complex|nuclear speck|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|multicellular organismal development|cell proliferation|RNA splicing|regulation of catalytic activity|",DNA binding|RNA binding|protein phosphatase inhibitor activity|protein binding|protein phosphatase type 1 regulator activity|,8,0.8,10.9,5,1.6,9.87,1.4,16.9,16.9,0.0198,0,0,0.5,2.3
ENSMUSG00000025915,SGK3,serum/glucocorticoid regulated kinase 3,endosome|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|,protein phosphorylation|phosphorylation|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphatidylinositol binding|",10,0.6,6.84,10,0.4,9.98,0.5,16.2,16.2,0.0211,0,0,0.3,0.9
ENSMUSG00000021670,HMGCR,3-hydroxy-3-methylglutaryl-Coenzyme A reductase,peroxisomal membrane|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|cholesterol biosynthetic process|ubiquinone metabolic process|steroid metabolic process|cholesterol metabolic process|positive regulation of cell proliferation|isoprenoid biosynthetic process|visual learning|embryo development|negative regulation of striated muscle cell apoptotic process|positive regulation of cardiac muscle cell apoptotic process|coenzyme A metabolic process|sterol biosynthetic process|positive regulation of stress-activated MAPK cascade|negative regulation of apoptotic process|negative regulation of MAP kinase activity|negative regulation of vasodilation|positive regulation of skeletal muscle tissue development|positive regulation of smooth muscle cell proliferation|protein tetramerization|oxidation-reduction process|negative regulation of wound healing|negative regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of ERK1 and ERK2 cascade|,"hydroxymethylglutaryl-CoA reductase (NADPH) activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|hydroxymethylglutaryl-CoA reductase activity|protein homodimerization activity|NADP binding|coenzyme binding|NADPH binding|",10,1.4,7.91,10,0.9,9.89,1.1,16.2,16.2,0.0211,0,0,0.6,2.1
ENSMUSG00000024477,PGGT1B,"protein geranylgeranyltransferase type I, beta subunit",CAAX-protein geranylgeranyltransferase complex|,positive regulation of cell proliferation|protein geranylgeranylation|response to cytokine|positive regulation of cell cycle|negative regulation of nitric-oxide synthase biosynthetic process|,catalytic activity|prenyltransferase activity|protein geranylgeranyltransferase activity|CAAX-protein geranylgeranyltransferase activity|CAAX-protein geranylgeranyltransferase activity|drug binding|zinc ion binding|zinc ion binding|transferase activity|isoprenoid binding|peptide binding|metal ion binding|,6,1.9,13.7,6,0.6,7.08,1.9,16.2,16.2,0.0211,0,0,0.3,3.5
ENSMUSG00000079507,H2-Q1,"histocompatibility 2, Q region locus 1",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|cell surface|membrane|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,immune system process|antigen processing and presentation of peptide antigen via MHC class I|antigen processing and presentation|,receptor binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,0.8,5.76,10,1.8,14.2,1.6,16.1,16.1,0.0213,0,0,0.4,2.9
ENSMUSG00000006273,ATP6V1B2,"ATPase, H+ transporting, lysosomal V1 subunit B2","cytoplasm|lysosomal membrane|cytosol|plasma membrane|microvillus|membrane|integral component of membrane|proton-transporting two-sector ATPase complex, catalytic domain|proton-transporting V-type ATPase, V1 domain|intracellular membrane-bounded organelle|extracellular vesicular exosome|",transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|ATP metabolic process|,"ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|",6,1.1,3.55,7,0.7,13.9,0.9,16,16,0.0214,0,0,0.5,1.7
ENSMUSG00000034617,MTRR,5-methyltetrahydrofolate-homocysteine methyltransferase reductase,nucleus|cytoplasm|cytosol|intermediate filament cytoskeleton|,DNA methylation|cellular amino acid biosynthetic process|methionine biosynthetic process|folic acid metabolic process|protein stabilization|oxidation-reduction process|,"iron ion binding|FMN binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen|oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor|[methionine synthase] reductase activity|[methionine synthase] reductase activity|aquacobalamin reductase activity|flavin adenine dinucleotide binding|",9,0.7,12.6,8,1,4.28,1,15.8,15.8,0.0219,0,0,0.5,1.6
ENSMUSG00000060038,DHPS,deoxyhypusine synthase,cellular_component|,peptidyl-lysine modification to peptidyl-hypusine|positive regulation of T cell proliferation|glucose homeostasis|deoxyhypusine biosynthetic process from spermidine|protein homotetramerization|,transferase activity|deoxyhypusine synthase activity|,3,1.6,14.6,3,-0.8,4.96,1.6,15.4,15.4,0.0228,0,0,1.1,3
ENSMUSG00000019432,DDX39B,DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B,transcription export complex|nucleus|spliceosomal complex|U4 snRNP|U6 snRNP|cytoplasm|,"spliceosomal complex assembly|mRNA splicing, via spliceosome|ATP catabolic process|mRNA processing|mRNA export from nucleus|transport|RNA splicing|RNA secondary structure unwinding|positive regulation of DNA-templated transcription, elongation|viral mRNA export from host cell nucleus|mRNA transport|negative regulation of DNA damage checkpoint|",nucleotide binding|nucleic acid binding|RNA binding|ATP-dependent RNA helicase activity|helicase activity|ATP binding|RNA-dependent ATPase activity|hydrolase activity|U6 snRNA binding|U4 snRNA binding|ATP-dependent protein binding|poly(A) RNA binding|,8,0,0,8,0.9,17.2,0.9,15.3,15.3,0.0231,0,0,0.5,1.7
ENSMUSG00000020532,ACACA,acetyl-Coenzyme A carboxylase alpha,cytoplasm|mitochondrion|cytosol|extracellular vesicular exosome|,tissue homeostasis|acetyl-CoA metabolic process|acetyl-CoA metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid biosynthetic process|metabolic process|response to organic cyclic compound|multicellular organismal protein metabolic process|protein homotetramerization|lipid homeostasis|,nucleotide binding|catalytic activity|acetyl-CoA carboxylase activity|acetyl-CoA carboxylase activity|acetyl-CoA carboxylase activity|biotin carboxylase activity|protein binding|ATP binding|biotin binding|ligase activity|kinase binding|metal ion binding|,10,-0.6,6.85,10,-1,9.48,-0.8,15,-15,0.0237,0,0,-1.5,-0.4
ENSMUSG00000031972,ACTA1,"actin, alpha 1, skeletal muscle",stress fiber|extracellular space|cytoplasm|cytoskeleton|striated muscle thin filament|striated muscle thin filament|actin filament|actin cytoskeleton|sarcomere|protein complex|extracellular vesicular exosome|blood microparticle|,skeletal muscle thin filament assembly|skeletal muscle fiber development|,nucleotide binding|protein binding|ATP binding|,9,1,2.41,9,1.7,14.5,1.6,14.9,14.9,0.024,0,0,0.4,3
ENSMUSG00000013593,NDUFS2,NADH dehydrogenase (ubiquinone) Fe-S protein 2,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain|,transport|response to oxidative stress|oxidation-reduction process|,"NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H|metal ion binding|quinone binding|NAD binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",8,0.8,12.8,9,0.6,2.41,0.7,14.8,14.8,0.0242,0,0,0.4,1.4
ENSMUSG00000032175,TYK2,tyrosine kinase 2,nucleus|cytoplasm|cytoskeleton|membrane|extracellular vesicular exosome|,protein phosphorylation|phosphorylation|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|growth hormone receptor binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|type 1 angiotensin receptor binding|",10,0.5,8.76,10,0.4,6.39,0.5,14.4,14.4,0.0252,0,0,0.2,0.8
ENSMUSG00000022897,DYRK1A,dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a,nucleus|nucleus|nuclear speck|ribonucleoprotein complex|,"regulation of alternative mRNA splicing, via spliceosome|protein phosphorylation|circadian rhythm|phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|peptidyl-tyrosine phosphorylation|negative regulation of DNA damage response, signal transduction by p53 class mediator|protein autophosphorylation|positive regulation of protein deacetylation|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|protein self-association|tau protein binding|",10,1.5,12,10,1.5,2.72,1.5,14.4,14.4,0.0252,0,0,1,2.6
ENSMUSG00000032409,ATR,ataxia telangiectasia and Rad3 related,XY body|nucleus|chromosome|PML body|,"DNA damage checkpoint|DNA damage checkpoint|DNA repair|protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|negative regulation of DNA replication|phosphorylation|peptidyl-serine phosphorylation|cellular response to UV|regulation of protein binding|positive regulation of DNA damage response, signal transduction by p53 class mediator|protein autophosphorylation|cellular response to gamma radiation|replicative senescence|","nucleotide binding|DNA binding|protein kinase activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|MutLalpha complex binding|MutSalpha complex binding|",9,0.7,8.56,9,1.3,8.3,1.1,14.2,14.2,0.0259,0,0,0.7,1.8
ENSMUSG00000023846,RIOK2,RIO kinase 2 (yeast),cellular_component|,protein phosphorylation|biological_process|phosphorylation|,"nucleotide binding|catalytic activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,1.7,8.44,9,1.1,6.99,1.3,14,14,0.0264,0,0,0.7,2.5
ENSMUSG00000035078,MTMR9,myotubularin related protein 9,cytoplasm|,dephosphorylation|regulation of catalytic activity|,protein binding|phosphatase activity|enzyme regulator activity|,10,0.3,2.25,10,0.5,12.5,0.4,14,14,0.0264,0,0,0.2,0.8
ENSMUSG00000033628,PIK3C3,"phosphoinositide-3-kinase, class 3",endosome|late endosome|phosphatidylinositol 3-kinase complex|membrane|midbody|phagocytic vesicle|,autophagic vacuole assembly|cytokinesis|protein phosphorylation|autophagy|endosome organization|cell cycle|phosphorylation|protein processing|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol-3-phosphate biosynthetic process|early endosome to late endosome transport|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|regulation of protein secretion|cell division|,"nucleotide binding|protein kinase activity|protein binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|phosphatidylinositol 3-kinase activity|",8,-0.9,5.52,7,1.4,11.6,1.3,13.9,13.9,0.0267,0,0,0.5,2.5
ENSMUSG00000018861,FDXR,ferredoxin reductase,mitochondrion|mitochondrion|mitochondrial inner membrane|,lipid metabolic process|transport|steroid metabolic process|cholesterol metabolic process|oxidation-reduction process|NADPH oxidation|,NADPH-adrenodoxin reductase activity|oxidoreductase activity|NADPH binding|,10,0.9,8.66,10,0.8,5.43,0.8,13.6,13.6,0.0275,0,0,0.4,1.6
ENSMUSG00000029366,DCK,deoxycytidine kinase,nucleus|cytosol|,nucleobase-containing compound metabolic process|pyrimidine nucleotide metabolic process|deoxyribonucleoside monophosphate biosynthetic process|nucleotide biosynthetic process|phosphorylation|drug metabolic process|deoxycytidine metabolic process|,nucleotide binding|magnesium ion binding|deoxycytidine kinase activity|ATP binding|drug binding|kinase activity|transferase activity|nucleoside kinase activity|pyrimidine deoxyribonucleoside binding|protein homodimerization activity|,9,1.2,16.2,9,0,0,1.2,13.3,13.3,0.0285,0,0,0.8,2
ENSMUSG00000024727,TRPM6,"transient receptor potential cation channel, subfamily M, member 6",membrane|integral component of membrane|apical plasma membrane|brush border membrane|,protein phosphorylation|transport|ion transport|calcium ion transport|response to toxic substance|phosphorylation|metal ion transport|ion transmembrane transport|transmembrane transport|calcium ion transmembrane transport|,"nucleotide binding|protein serine/threonine kinase activity|ion channel activity|cation channel activity|calcium channel activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,2,15.7,10,0.4,1.22,2,13.2,13.2,0.0289,0,0,0.4,4
ENSMUSG00000022295,ATP6V1C1,"ATPase, H+ transporting, lysosomal V1 subunit C1","cytoplasm|lysosomal membrane|plasma membrane|cytoplasmic vesicle|proton-transporting V-type ATPase, V1 domain|apical part of cell|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|hydrogen ion transmembrane transport|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrogen ion transmembrane transporter activity|",9,0.7,5.43,9,0.7,7.94,0.7,13,13,0.0295,0,0,0.3,1.3
ENSMUSG00000033938,NDUFB7,"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial intermembrane space|membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|,10,0.9,8.61,10,0.9,4.66,0.9,12.9,12.9,0.0298,0,0,0.4,1.7
ENSMUSG00000002963,PNKP,polynucleotide kinase 3'- phosphatase,nucleus|membrane|,"DNA repair|cellular response to DNA damage stimulus|response to oxidative stress|metabolic process|phosphorylation|dephosphorylation|DNA damage response, detection of DNA damage|nucleotide phosphorylation|polynucleotide 3' dephosphorylation|",nucleotide binding|catalytic activity|ATP binding|kinase activity|transferase activity|hydrolase activity|nucleotide kinase activity|polynucleotide 3'-phosphatase activity|ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity|,8,1,5.7,7,0.8,7.72,1,12.9,12.9,0.0298,0,0,0.5,1.7
ENSMUSG00000026181,PPM1F,protein phosphatase 1F (PP2C domain containing),cytosol|protein complex|perinuclear region of cytoplasm|,"negative regulation of protein kinase activity|protein dephosphorylation|apoptotic process|positive regulation of gene expression|positive regulation of epithelial cell migration|positive regulation of cell-substrate adhesion|histone dephosphorylation|negative regulation of peptidyl-serine phosphorylation|cellular response to drug|peptidyl-threonine dephosphorylation|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of protein kinase activity by regulation of protein phosphorylation|negative regulation of transcription, DNA-templated|positive regulation of growth|positive regulation of chemotaxis|positive regulation of stress fiber assembly|positive regulation of focal adhesion assembly|intrinsic apoptotic signaling pathway|",catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|calmodulin-dependent protein phosphatase activity|metal ion binding|,10,0.6,2.04,10,0.5,11.4,0.5,12.9,12.9,0.0298,0,0,0.2,0.9
ENSMUSG00000002250,PPARD,peroxisome proliferator activator receptor delta,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|placenta development|proteoglycan metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|lipid metabolic process|lipid metabolic process|vitamin A metabolic process|G-protein coupled receptor signaling pathway|embryo implantation|cell proliferation|positive regulation of cell proliferation|axon ensheathment|epidermis development|phospholipid biosynthetic process|mRNA transcription|cellular process|positive regulation of phosphatidylinositol 3-kinase signaling|negative regulation of smooth muscle cell migration|fatty acid oxidation|cell differentiation|cell differentiation|negative regulation of cell growth|intracellular receptor signaling pathway|intracellular receptor signaling pathway|cell-substrate adhesion|positive regulation of insulin secretion|negative regulation of collagen biosynthetic process|wound healing|regulation of cell proliferation|anagen|negative regulation of apoptotic process|positive regulation of catalytic activity|steroid hormone mediated signaling pathway|keratinocyte proliferation|regulation of fat cell differentiation|positive regulation of epidermis development|positive regulation of transcription, DNA-templated|positive regulation of vasodilation|negative regulation of smooth muscle cell proliferation|negative regulation of epithelial cell proliferation|negative regulation of inflammatory response|regulation of insulin secretion|keratinocyte migration|adipose tissue development|cellular response to hypoxia|apoptotic signaling pathway|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|transcription coactivator activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|fatty acid binding|enzyme activator activity|drug binding|zinc ion binding|lipid binding|prostacyclin receptor activity|sequence-specific DNA binding|metal ion binding|retinoid X receptor binding|protein heterodimerization activity|NF-kappaB binding|linoleic acid binding|,10,0.1,0.104,10,-1.6,16.1,-1.5,12.8,-12.8,0.0303,0,0,-3,-0.8
ENSMUSG00000027009,ITGA4,integrin alpha 4,plasma membrane|cell-cell junction|integrin complex|external side of plasma membrane|cell surface|cell surface|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,blood vessel remodeling|cell adhesion|heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|leukocyte cell-cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|heart development|single organismal cell-cell adhesion|cell migration|face development|mesenchyme development|chorio-allantoic fusion|visceral serous pericardium development|T cell migration|negative regulation of protein homodimerization activity|,fibronectin binding|metal ion binding|cell adhesion molecule binding|,10,1.1,3.5,10,0.6,9.41,0.6,12.1,12.1,0.0333,0,0,0.2,1.3
ENSMUSG00000023192,GRM2,"glutamate receptor, metabotropic 2",intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|axon|presynaptic membrane|presynaptic membrane|cell projection|neuron projection|synapse|,"signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|synaptic transmission|glutamate secretion|regulation of synaptic transmission, glutamatergic|",group II metabotropic glutamate receptor activity|group II metabotropic glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|calcium channel regulator activity|,10,-1.8,15.1,10,1.4,0.603,-1.7,12.1,-12.1,0.0333,0,0,-3,-0.4
ENSMUSG00000009566,FPGS,folylpolyglutamyl synthetase,cytoplasm|mitochondrion|mitochondrial inner membrane|membrane|,one-carbon metabolic process|biosynthetic process|folic acid-containing compound biosynthetic process|tetrahydrofolylpolyglutamate biosynthetic process|,nucleotide binding|tetrahydrofolylpolyglutamate synthase activity|ATP binding|ligase activity|,8,0.7,9.36,8,-1,4.85,0.7,12.1,12.1,0.0333,0,0,0.4,1.7
ENSMUSG00000023089,NDUFA5,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain complex I|respiratory chain|,transport|respiratory electron transport chain|oxidation-reduction process|,"NADH dehydrogenase (ubiquinone) activity|oxidoreductase activity, acting on NAD(P)H|",10,-0.7,7.39,10,-0.8,4.68,-0.8,11.6,-11.6,0.036,0,0,-2,0.7
ENSMUSG00000036057,PTPN23,"protein tyrosine phosphatase, non-receptor type 23",nucleus|cytoplasm|endosome|early endosome|cytoskeleton|cilium|cytoplasmic vesicle|ciliary basal body|cell projection|extracellular vesicular exosome|,protein dephosphorylation|transport|protein transport|dephosphorylation|cell projection organization|regulation of cell migration|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|cilium morphogenesis|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,9,2,12.3,8,-0.3,4.27,-1.1,11.5,-11.5,0.0367,0,0,-3,3.4
ENSMUSG00000021520,UQCRB,ubiquinol-cytochrome c reductase binding protein,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex III|membrane|respiratory chain|,"mitochondrial electron transport, ubiquinol to cytochrome c|transport|oxidation-reduction process|",None,7,0.7,9.72,7,0.4,3.73,0.6,11.5,11.5,0.0367,0,0,0.2,1.2
ENSMUSG00000025537,PHKG1,phosphorylase kinase gamma 1,phosphorylase kinase complex|,carbohydrate metabolic process|glycogen metabolic process|glycogen biosynthetic process|protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|phosphorylase kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|tau-protein kinase activity|",10,0.9,3.94,10,0.7,7.9,0.8,11.4,11.4,0.0372,0,0,0.4,1.6
ENSMUSG00000040274,CDK6,cyclin-dependent kinase 6,cyclin-dependent protein kinase holoenzyme complex|ruffle|nucleus|cytoplasm|cell projection|,positive regulation of cell-matrix adhesion|hematopoietic progenitor cell differentiation|type B pancreatic cell development|protein phosphorylation|cell cycle|Notch signaling pathway|Notch signaling pathway|regulation of gene expression|positive regulation of gene expression|phosphorylation|hemopoiesis|cell differentiation|T cell differentiation in thymus|gliogenesis|regulation of cell proliferation|cell dedifferentiation|negative regulation of myeloid cell differentiation|regulation of erythrocyte differentiation|negative regulation of osteoblast differentiation|negative regulation of cell cycle|positive regulation of fibroblast proliferation|negative regulation of epithelial cell proliferation|cell division|hematopoietic stem cell differentiation|negative regulation of cellular senescence|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|",8,0.7,3.31,8,-1.3,10.6,-1.2,11.1,-11.1,0.0389,0,0,-3,0.3
ENSMUSG00000022971,IFNAR2,interferon (alpha and beta) receptor 2,extracellular region|extracellular space|extracellular space|integral component of plasma membrane|membrane|integral component of membrane|,regulation of transcription from RNA polymerase II promoter|cell proliferation|response to interferon-alpha|type I interferon signaling pathway|,type I interferon receptor activity|type I interferon receptor activity|protein kinase binding|type I interferon binding|,10,0.8,8.37,10,0.3,4.43,0.4,10.8,10.8,0.041,0,0,0.2,1.1
ENSMUSG00000020525,PPM1D,"protein phosphatase 1D magnesium-dependent, delta isoform",None,G2/M transition of mitotic cell cycle|protein dephosphorylation|cell cycle|response to bacterium|dephosphorylation|peptidyl-threonine dephosphorylation|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|magnesium-dependent protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,0.7,6.53,10,0.4,4.81,0.5,10.3,10.3,0.0439,0,0,0.2,1.2
ENSMUSG00000027296,ITPKA,"inositol 1,4,5-trisphosphate 3-kinase A",dendritic spine|,inositol metabolic process|protein phosphorylation|phosphorylation|actin cytoskeleton organization|regulation of synaptic plasticity|positive regulation of dendritic spine morphogenesis|dendritic spine maintenance|,"nucleotide binding|calmodulin-dependent protein kinase activity|calmodulin binding|ATP binding|inositol-1,4,5-trisphosphate 3-kinase activity|kinase activity|transferase activity|Rac GTPase binding|",10,0.1,0.0658,10,-1,12.9,-1,9.99,-9.99,0.0462,0,0,-1.8,-0.4
ENSMUSG00000026659,DUSP12,dual specificity phosphatase 12,cytoplasm|,protein dephosphorylation|protein dephosphorylation|dephosphorylation|positive regulation of glucokinase activity|positive regulation of glucokinase activity|,phosphoprotein phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|kinase binding|,7,1.3,3.21,7,0.7,8.83,0.9,9.92,9.92,0.0467,0,0,0.4,1.9
ENSMUSG00000045962,WNK1,WNK lysine deficient protein kinase 1,cytoplasm|cytoplasm|,positive regulation of systemic arterial blood pressure|protein phosphorylation|protein phosphorylation|ion transport|negative regulation of phosphatase activity|phosphorylation|negative regulation of kinase activity|intracellular signal transduction|protein autophosphorylation|regulation of cellular process|negative regulation of protein serine/threonine kinase activity|negative regulation of pancreatic juice secretion|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase inhibitor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|chloride channel inhibitor activity|potassium channel inhibitor activity|protein kinase binding|phosphatase binding|protein serine/threonine kinase inhibitor activity|",9,1.4,11,9,0.3,1.73,0.7,9.79,9.79,0.0477,0,0,0.3,2.2
ENSMUSG00000021111,PAPOLA,poly (A) polymerase alpha,nucleus|nucleus|cytoplasm|,"mRNA splicing, via spliceosome|termination of RNA polymerase II transcription|mRNA polyadenylation|mRNA processing|RNA 3'-end processing|RNA polyadenylation|",nucleotide binding|RNA binding|polynucleotide adenylyltransferase activity|ATP binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,9,0.5,2.08,9,0.9,8.54,0.7,9.71,9.71,0.0483,0,0,0.3,1.6
ENSMUSG00000006728,CDK4,cyclin-dependent kinase 4,cyclin-dependent protein kinase holoenzyme complex|cyclin-dependent protein kinase holoenzyme complex|chromatin|nucleus|nucleus|transcription factor complex|nucleolus|cytoplasm|cytosol|tight junction|membrane|nuclear membrane|perinuclear region of cytoplasm|,G1/S transition of mitotic cell cycle|protein phosphorylation|protein phosphorylation|cell cycle|signal transduction|positive regulation of cell proliferation|response to organic substance|response to lead ion|regulation of gene expression|positive regulation of G2/M transition of mitotic cell cycle|phosphorylation|response to testosterone|regulation of cell proliferation|response to drug|positive regulation of apoptotic process|positive regulation of translation|positive regulation of cell size|positive regulation of fibroblast proliferation|cell division|regulation of cell cycle|negative regulation of cell cycle arrest|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|protein complex binding|",10,-0.9,3.89,9,-1.2,6.57,-1.1,9.64,-9.64,0.0488,0,0,-2,-0.3
ENSMUSG00000033885,PXK,PX domain containing serine/threonine kinase,nucleus|cytoplasm|cytoplasm|microtubule organizing center|plasma membrane|plasma membrane|membrane|,protein phosphorylation|inflammatory response|negative regulation of ATPase activity|negative regulation of ion transport|,"actin binding|protein kinase activity|ATP binding|protein C-terminus binding|transferase activity, transferring phosphorus-containing groups|phosphatidylinositol binding|",10,-0.2,0.967,10,-0.7,10.4,-0.7,9.43,-9.43,0.0507,0,0,-1.4,-0.2
ENSMUSG00000022956,ATP5O,"ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit","mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|plasma membrane|membrane|extracellular vesicular exosome|",ATP catabolic process|ATP biosynthetic process|transport|ion transport|ATP synthesis coupled proton transport|proton transport|mitochondrial ATP synthesis coupled proton transport|ATP metabolic process|,"steroid binding|drug binding|ATPase activity|protein complex binding|proton-transporting ATP synthase activity, rotational mechanism|",7,-1,5.99,8,0.6,7.1,-1,9.4,-9.4,0.051,0,0,-2,1
ENSMUSG00000031155,PIM2,proviral integration site 2,None,"G1/S transition of mitotic cell cycle|protein phosphorylation|protein phosphorylation|apoptotic process|cell cycle|negative regulation of cell proliferation|apoptotic mitochondrial changes|positive regulation of autophagy|phosphorylation|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of transcription, DNA-templated|protein stabilization|protein stabilization|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.9,11.9,10,0.2,1.65,0.3,9.34,9.34,0.0516,0,0,0.1,3.7
ENSMUSG00000023942,SLC29A1,"solute carrier family 29 (nucleoside transporters), member 1",plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|,transport|nucleoside transport|nucleoside transport|uridine transport|sleep|regulation of excitatory postsynaptic membrane potential|nucleoside transmembrane transport|nucleoside transmembrane transport|,nucleoside transmembrane transporter activity|nucleoside transmembrane transporter activity|,10,-0.6,3.78,10,-0.9,6.44,-0.8,9.33,-9.33,0.0517,0,0,-1.7,-0.3
ENSMUSG00000018428,AKAP1,A kinase (PRKA) anchor protein 1,mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial matrix|endoplasmic reticulum|lipid particle|membrane|membrane|integral component of membrane|mitochondrial crista|neuromuscular junction|postsynaptic membrane|,negative regulation of cardiac muscle hypertrophy|negative regulation of protein dephosphorylation|negative regulation of NFAT protein import into nucleus|,RNA binding|protein binding|microtubule binding|protein kinase binding|protein phosphatase binding|protein domain specific binding|protein phosphatase 2B binding|protein complex scaffold|protein kinase A regulatory subunit binding|poly(A) RNA binding|beta-tubulin binding|,10,0.3,1.7,10,0.7,9.25,0.5,9.24,9.24,0.0526,0,0,0.2,1.6
ENSMUSG00000018589,GLRA2,"glycine receptor, alpha 2 subunit",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|neuropeptide signaling pathway|chloride transmembrane transport|,extracellular ligand-gated ion channel activity|chloride channel activity|glycine binding|extracellular-glycine-gated chloride channel activity|transmitter-gated ion channel activity|,10,-0.6,4.74,10,-0.4,4.87,-0.5,9.05,-9.05,0.0547,0,0,-1.2,-0.2
ENSMUSG00000002997,PRKAR2B,"protein kinase, cAMP dependent regulatory, type II beta",cytoplasm|mitochondrial inner membrane|centrosome|plasma membrane|cAMP-dependent protein kinase complex|membrane|membrane raft|perinuclear region of cytoplasm|ciliary base|,regulation of protein phosphorylation|fatty acid metabolic process|learning|regulation of protein kinase activity|regulation of protein kinase activity|negative regulation of cAMP-dependent protein kinase activity|,nucleotide binding|cAMP-dependent protein kinase inhibitor activity|protein binding|cAMP-dependent protein kinase regulator activity|cAMP-dependent protein kinase regulator activity|protein domain specific binding|cAMP binding|ubiquitin protein ligase binding|protein kinase A catalytic subunit binding|,10,-0.6,5.07,10,-0.7,4.37,-0.6,9.04,-9.04,0.0548,0,0,-1.4,-0.2
ENSMUSG00000031264,BTK,Bruton agammaglobulinemia tyrosine kinase,intracellular|nucleus|cytoplasm|cytosol|plasma membrane|membrane|cytoplasmic vesicle|mast cell granule|intracellular membrane-bounded organelle|membrane raft|perinuclear region of cytoplasm|,"immune system process|histamine secretion by mast cell|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|I-kappaB kinase/NF-kappaB signaling|response to organic substance|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cellular response to reactive oxygen species|intracellular signal transduction|innate immune response|protein autophosphorylation|cell maturation|cellular response to molecule of fungal origin|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|phosphatidylinositol-3,4,5-trisphosphate binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|metal ion binding|",10,1.1,11,10,0.1,0.191,1,8.99,8.99,0.0554,0,0,0.4,1.9
ENSMUSG00000033014,TRIM33,tripartite motif-containing 33,intracellular|nucleus|nucleus|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein ubiquitination|regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|","DNA binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|co-SMAD binding|R-SMAD binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",8,0.9,3.94,8,0.4,5.39,0.4,8.88,8.88,0.0565,0,0,0.1,1.2
ENSMUSG00000057342,SPHK2,sphingosine kinase 2,lysosome|lysosomal membrane|cytosol|cytosol|membrane|membrane|,blood vessel development|sphinganine-1-phosphate biosynthetic process|sphingosine metabolic process|protein kinase C-activating G-protein coupled receptor signaling pathway|brain development|metabolic process|cell proliferation|positive regulation of cell proliferation|phosphorylation|negative regulation of apoptotic process|lipid phosphorylation|,nucleotide binding|NAD+ kinase activity|diacylglycerol kinase activity|protein binding|ATP binding|sphinganine kinase activity|kinase activity|transferase activity|D-erythro-sphingosine kinase activity|D-erythro-sphingosine kinase activity|,10,0.4,3.16,10,0.7,6.91,0.5,8.81,8.81,0.0574,0,0,0.2,1.3
ENSMUSG00000022354,NDUFB9,"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|extracellular vesicular exosome|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,1,6.85,9,0.9,2.14,1,8.64,8.64,0.0595,0,0,0.4,1.9
ENSMUSG00000030869,NDUFAB1,"NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1",mitochondrion|mitochondrial respiratory chain complex I|respiratory chain|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|transport|protein lipoylation|oxidation-reduction process|,molecular_function|,7,-1.4,7.97,5,-0.7,2.08,-1.3,8.5,-8.5,0.0609,0,0,-2.8,-0.3
ENSMUSG00000040385,PPP1CA,"protein phosphatase 1, catalytic subunit, alpha isoform",protein phosphatase type 1 complex|nucleus|nucleus|nucleoplasm|cytoplasm|cytoplasm|glycogen granule|neuron projection|neuronal cell body|dendritic spine|perikaryon|extracellular vesicular exosome|MLL5-L complex|PTW/PP1 phosphatase complex|,carbohydrate metabolic process|glycogen metabolic process|regulation of glycogen biosynthetic process|regulation of glycogen catabolic process|regulation of translation|protein dephosphorylation|protein dephosphorylation|protein dephosphorylation|cell cycle|female meiotic division|cellular process|dephosphorylation|lung development|circadian regulation of gene expression|regulation of circadian rhythm|regulation of circadian rhythm|regulation of circadian rhythm|entrainment of circadian clock by photoperiod|rhythmic process|branching morphogenesis of an epithelial tube|cell division|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,phosphoprotein phosphatase activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein serine/threonine phosphatase activity|protein serine/threonine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|ribonucleoprotein complex binding|metal ion binding|,10,-0.7,5.2,8,-0.8,3.67,-0.8,8.47,-8.47,0.0613,0,0,-2,1.4
ENSMUSG00000019942,CDK1,cyclin-dependent kinase 1,nucleus|cytoplasm|mitochondrion|centrosome|cytoskeleton|spindle microtubule|membrane|midbody|extracellular vesicular exosome|mitotic spindle|,"protein complex assembly|protein phosphorylation|apoptotic process|cell cycle|mitotic nuclear division|mitotic G2 DNA damage checkpoint|cell aging|response to organonitrogen compound|positive regulation of gene expression|phosphorylation|histone phosphorylation|peptidyl-serine phosphorylation|chromosome condensation|organ regeneration|positive regulation of protein import into nucleus, translocation|protein localization to kinetochore|negative regulation of apoptotic process|response to ethanol|positive regulation of DNA replication|positive regulation of mitotic cell cycle|cell division|positive regulation of cardiac muscle cell proliferation|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|Hsp70 protein binding|histone kinase activity|",5,1.6,10.4,6,0.3,0.687,1.6,8.38,8.38,0.0623,0,0,0.8,3
ENSMUSG00000035929,H2-Q4,"histocompatibility 2, Q region locus 4",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|cell surface|membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,None,receptor binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,0.8,5.81,10,0.3,3.93,0.4,8.37,8.37,0.0625,0,0,0.1,1.2
ENSMUSG00000030815,PHKG2,"phosphorylase kinase, gamma 2 (testis)",phosphorylase kinase complex|,carbohydrate metabolic process|glycogen metabolic process|glycogen biosynthetic process|protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|phosphorylase kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.2,4.82,10,0.7,4.4,0.8,8.36,8.36,0.0626,0,0,0.3,1.8
ENSMUSG00000037216,LIPT1,lipoyltransferase 1,mitochondrion|,cellular protein modification process|biological_process|protein lipoylation|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,-1,4.45,9,1.2,8.04,1.2,8.15,8.15,0.0654,0,0,-1.1,3
ENSMUSG00000000308,CKMT1,"creatine kinase, mitochondrial 1, ubiquitous",mitochondrion|mitochondrial inner membrane|membrane|extracellular vesicular exosome|,phosphorylation|,"nucleotide binding|catalytic activity|creatine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.5,3.83,10,-0.5,4.6,-0.5,8.08,-8.08,0.0663,0,0,-1.1,-0.1
ENSMUSG00000036943,RAB8B,"RAB8B, member RAS oncogene family",mitochondrion|peroxisomal membrane|plasma membrane|membrane|cytoplasmic vesicle|phagocytic vesicle|perinuclear region of cytoplasm|cell tip|extracellular vesicular exosome|,transport|small GTPase mediated signal transduction|protein transport|antigen processing and presentation|positive regulation of cell projection organization|adherens junction organization|protein import into peroxisome membrane|positive regulation of corticotropin secretion|,nucleotide binding|receptor binding|protein binding|GTP binding|GDP binding|TPR domain binding|,10,-0.6,6.22,10,0.5,7.15,-0.8,8,-8,0.0674,0,0,-2,1.1
ENSMUSG00000024493,LARS,leucyl-tRNA synthetase,nucleus|cytoplasm|,translation|tRNA aminoacylation for protein translation|leucyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA editing activity|aminoacyl-tRNA ligase activity|leucine-tRNA ligase activity|ATP binding|ligase activity|,9,-0.7,6.88,7,-0.4,1.98,-0.6,7.8,-7.8,0.0703,0,0,-1.6,-0.2
ENSMUSG00000024210,IP6K3,inositol hexaphosphate kinase 3,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|inositol phosphate biosynthetic process|phosphatidylinositol metabolic process|,"nucleotide binding|inositol hexakisphosphate 6-kinase activity|inositol hexakisphosphate 5-kinase activity|ATP binding|inositol-1,4,5-trisphosphate 3-kinase activity|kinase activity|transferase activity|inositol hexakisphosphate 1-kinase activity|inositol hexakisphosphate 3-kinase activity|",10,1,9.56,10,0.3,0.937,1,7.79,7.79,0.0705,0,0,0.3,1.8
ENSMUSG00000033981,GRIA2,"glutamate receptor, ionotropic, AMPA2 (alpha 2)",endoplasmic reticulum|plasma membrane|integral component of plasma membrane|synaptic vesicle|cell surface|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|dendrite|growth cone|synaptic vesicle membrane|asymmetric synapse|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|dendrite cytoplasm|presynaptic membrane|neuron projection|neuronal cell body|terminal bouton|dendritic spine|dendritic shaft|perikaryon|protein complex|synapse|synapse|postsynaptic membrane|postsynaptic membrane|,"regulation of receptor recycling|transport|ion transport|synaptic transmission|synaptic transmission|receptor internalization|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|establishment of protein localization|positive regulation of synaptic transmission|protein tetramerization|regulation of synaptic transmission, glutamatergic|",receptor activity|ionotropic glutamate receptor activity|ionotropic glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|kainate selective glutamate receptor activity|protein kinase binding|PDZ domain binding|identical protein binding|,10,0.5,1.96,10,0.5,6.04,0.5,7.69,7.69,0.0721,0,0,0.1,1.3
ENSMUSG00000020901,PIK3R5,"phosphoinositide-3-kinase, regulatory subunit 5, p101","nucleus|cytoplasm|phosphatidylinositol 3-kinase complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex|membrane|",phosphorylation|regulation of phosphatidylinositol 3-kinase activity|,kinase activity|transferase activity|1-phosphatidylinositol-3-kinase regulator activity|,10,-0.4,5.02,10,-0.3,3.09,-0.3,7.48,-7.48,0.0756,0,0,-0.8,-0.1
ENSMUSG00000071415,RPL23,ribosomal protein L23,nucleolus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|cytosolic ribosome|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,structural constituent of ribosome|protein binding|poly(A) RNA binding|,10,0.5,2.49,9,0.3,5.36,0.3,7.41,7.41,0.0768,0,0,0.1,0.9
ENSMUSG00000021420,FARS2,phenylalanine-tRNA synthetase 2 (mitochondrial),cytoplasm|mitochondrion|,translation|tRNA aminoacylation for protein translation|phenylalanyl-tRNA aminoacylation|tRNA processing|tRNA aminoacylation|,tRNA binding|nucleotide binding|magnesium ion binding|aminoacyl-tRNA ligase activity|phenylalanine-tRNA ligase activity|ATP binding|ligase activity|,7,0.4,1.65,7,0.6,6.27,0.6,7.38,7.38,0.0775,0,0,0.1,1.7
ENSMUSG00000025949,PIKFYVE,"phosphoinositide kinase, FYVE finger containing",endosome|cytosol|cell-cell junction|endosome membrane|vesicle membrane|membrane|cytoplasmic vesicle|early endosome membrane|membrane raft|perinuclear region of cytoplasm|,"phosphorylation|myelin assembly|protein localization to nucleus|intracellular signal transduction|retrograde transport, endosome to Golgi|cellular protein metabolic process|phosphatidylinositol metabolic process|phosphatidylinositol phosphorylation|",nucleotide binding|1-phosphatidylinositol-3-phosphate 5-kinase activity|protein binding|ATP binding|zinc ion binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|transferase activity|metal ion binding|,10,1.1,1.85,10,0.9,5.9,1,7.32,7.32,0.0788,0,0,0.3,2
ENSMUSG00000051980,CASR,calcium-sensing receptor,nucleus|cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|axon|neuron projection|neuronal cell body|axon terminus|,ossification|calcium ion transport|cellular calcium ion homeostasis|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|JNK cascade|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of insulin secretion|positive regulation of ATPase activity|positive regulation of ATPase activity|vasodilation|positive regulation of vasoconstriction|branching morphogenesis of an epithelial tube|positive regulation of positive chemotaxis|regulation of calcium ion transport|calcium ion import|positive regulation of calcium ion import|,magnesium ion binding|signal transducer activity|G-protein coupled receptor activity|integrin binding|calcium ion binding|drug binding|polyamine binding|protein kinase binding|ion channel binding|,10,-0.2,0.423,10,-0.8,8.38,-0.7,7.3,-7.3,0.0792,0,0,-1.7,-0.2
ENSMUSG00000029454,MAPKAPK5,MAP kinase-activated protein kinase 5,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|,regulation of translation|protein phosphorylation|Ras protein signal transduction|Ras protein signal transduction|phosphorylation|negative regulation of TOR signaling|protein autophosphorylation|stress-induced premature senescence|stress-induced premature senescence|,"nucleotide binding|p53 binding|p53 binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase binding|",10,0.5,4.99,10,0.4,2.58,0.5,7.22,7.22,0.0808,0,0,0.1,1.4
ENSMUSG00000053907,MAT2A,"methionine adenosyltransferase II, alpha",cytosol|methionine adenosyltransferase complex|,S-adenosylmethionine biosynthetic process|S-adenosylmethionine biosynthetic process|one-carbon metabolic process|circadian rhythm|response to hormone|response to drug|response to cAMP|,nucleotide binding|methionine adenosyltransferase activity|methionine adenosyltransferase activity|ATP binding|amino acid binding|transferase activity|metal ion binding|,7,0.7,7.74,5,0.2,0.936,0.7,7.1,7.1,0.083,0,0,0.1,1.6
ENSMUSG00000032112,TRAPPC4,trafficking protein particle complex 4,endoplasmic reticulum|Golgi apparatus|Golgi stack|cis-Golgi network|plasma membrane|synaptic vesicle|membrane|TRAPP complex|cell junction|dendrite|synapse|postsynaptic membrane|,transport|ER to Golgi vesicle-mediated transport|vesicle-mediated transport|dendrite development|neurotransmitter receptor biosynthetic process|,protein binding|,7,1.6,3.42,7,-0.9,5.49,-0.7,7.01,-7.01,0.0848,0,0,-2,1.8
ENSMUSG00000056880,GADL1,glutamate decarboxylase-like 1,cellular_component|,biological_process|carboxylic acid metabolic process|,catalytic activity|aspartate 1-decarboxylase activity|lyase activity|carboxy-lyase activity|pyridoxal phosphate binding|,10,-1.5,9.77,10,0,0,-0.3,7.01,-7.01,0.0848,0,0,-2.8,-0.2
ENSMUSG00000029211,GABRA4,"gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4",plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|gamma-aminobutyric acid signaling pathway|central nervous system development|regulation of response to drug|,GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|chloride channel activity|,10,0.2,1.37,10,0.6,6.27,0.6,6.95,6.95,0.0859,0,0,0.1,1.5
ENSMUSG00000015214,MTMR1,myotubularin related protein 1,cytoplasm|plasma membrane|membrane|,dephosphorylation|,"phosphatidylinositol-3-phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0.5,4.71,10,0.6,2.61,0.5,6.94,6.94,0.0861,0,0,0.1,1.4
ENSMUSG00000001630,STK38L,serine/threonine kinase 38 like,cytoplasm|cytoplasm|cytoskeleton|actin cytoskeleton|membrane|,protein phosphorylation|protein phosphorylation|phosphorylation|intracellular signal transduction|regulation of cellular component organization|,"nucleotide binding|magnesium ion binding|actin binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.4,0.967,10,-1,6.58,-1,6.92,-6.92,0.0864,0,0,-2,-0.4
ENSMUSG00000018160,MED1,mediator complex subunit 1,chromatin|nucleus|nucleus|membrane|mediator complex|mediator complex|protein-DNA complex|,"negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|angiogenesis|in utero embryonic development|liver development|embryonic placenta development|lens development in camera-type eye|thyroid hormone mediated signaling pathway|ventricular trabecula myocardium morphogenesis|retinal pigment epithelium development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase I promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|thyroid hormone generation|androgen biosynthetic process|multicellular organismal development|brain development|heart development|lactation|positive regulation of cell proliferation|organ morphogenesis|positive regulation of gene expression|negative regulation of keratinocyte proliferation|keratinocyte differentiation|monocyte differentiation|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|organ regeneration|positive regulation of intracellular estrogen receptor signaling pathway|positive regulation of protein import into nucleus, translocation|mammary gland epithelial cell proliferation|positive regulation of mammary gland epithelial cell proliferation|embryonic heart tube development|embryonic hindlimb morphogenesis|embryonic hemopoiesis|peroxisome proliferator activated receptor signaling pathway|cellular response to hepatocyte growth factor stimulus|megakaryocyte development|mRNA transcription from RNA polymerase II promoter|camera-type eye development|negative regulation of apoptotic process|fat cell differentiation|fat cell differentiation|positive regulation of keratinocyte differentiation|negative regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|erythrocyte development|enucleate erythrocyte development|positive regulation of interferon-gamma-mediated signaling pathway|mammary gland branching involved in thelarche|mammary gland branching involved in pregnancy|epithelial cell proliferation involved in mammary gland duct elongation|positive regulation of G0 to G1 transition|ERK1 and ERK2 cascade|regulation of vitamin D receptor signaling pathway|cellular response to epidermal growth factor stimulus|cellular response to steroid hormone stimulus|cellular response to thyroid hormone stimulus|positive regulation of receptor activity|positive regulation of hepatocyte proliferation|regulation of RNA biosynthetic process|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|core promoter binding|core promoter binding|RNA polymerase II transcription cofactor activity|DNA binding|chromatin binding|chromatin binding|transcription cofactor activity|transcription coactivator activity|transcription coactivator activity|transcription coactivator activity|receptor activity|protein binding|transcription factor binding|transcription factor binding|ligand-dependent nuclear receptor binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|thyroid hormone receptor coactivator activity|chromatin DNA binding|protein complex binding|protein complex binding|nuclear hormone receptor binding|nuclear hormone receptor binding|mediator complex binding|vitamin D receptor binding|retinoic acid receptor binding|peroxisome proliferator activated receptor binding|thyroid hormone receptor binding|LBD domain binding|,6,-0.4,1.62,6,0.7,6.56,0.7,6.92,6.92,0.0864,0,0,-1.1,2
ENSMUSG00000036333,KIDINS220,kinase D-interacting substrate 220,late endosome|membrane|protein complex|,in utero embryonic development|positive regulation of neuron projection development|cytoplasmic transport|nerve growth factor signaling pathway|regulation of protein kinase activity|dendrite morphogenesis|cellular response to nerve growth factor stimulus|,protein kinase regulator activity|protein kinase binding|PDZ domain binding|,10,-0.6,6.73,10,-0.2,0.775,-0.5,6.88,-6.88,0.0873,0,0,-1.4,-0.1
ENSMUSG00000020907,RCVRN,recoverin,dendrite|,visual perception|visual perception|phototransduction|response to stimulus|regulation of calcium ion transport|,calcium ion binding|calcium ion binding|metal ion binding|,10,0.7,3.55,10,0.6,3.79,0.6,6.84,6.84,0.0881,0,0,0.1,1.6
ENSMUSG00000059534,UQCR10,"ubiquinol-cytochrome c reductase, complex III subunit X",mitochondrion|mitochondrial envelope|mitochondrial inner membrane|mitochondrial respiratory chain complex III|membrane|extracellular vesicular exosome|respiratory chain|,"mitochondrial electron transport, ubiquinol to cytochrome c|transport|biological_process|oxidation-reduction process|",molecular_function|,5,1.5,4.28,5,0.9,3.95,1.5,6.81,6.81,0.0888,0,0,-0.4,3
ENSMUSG00000078656,VPS25,vacuolar protein sorting 25 (yeast),nucleus|nucleolus|cytoplasm|mitochondrion|endosome|endosome membrane|membrane|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|protein transport|",protein homodimerization activity|,7,1.4,9.19,5,-0.5,0.835,1.4,6.8,6.8,0.0888,0,0,0.5,3
ENSMUSG00000039092,SPTLC3,"serine palmitoyltransferase, long chain base subunit 3",endoplasmic reticulum|membrane|integral component of membrane|serine C-palmitoyltransferase complex|,lipid metabolic process|sphingolipid metabolic process|metabolic process|biosynthetic process|sphingoid biosynthetic process|,"catalytic activity|serine C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|pyridoxal phosphate binding|",10,-0.1,0.309,10,-0.8,8.9,-0.8,6.73,-6.73,0.0904,0,0,-1.8,-0.2
ENSMUSG00000029516,CIT,citron,ruffle|cytoplasm|vacuole|plasma membrane|actin cytoskeleton|membrane|Golgi cisterna|neuronal cell body|,mitotic sister chromatid segregation|G2/M transition of mitotic cell cycle|cytokinesis|cytokinesis|protein phosphorylation|Golgi organization|cell cycle|mitotic nuclear division|metaphase/anaphase transition of mitotic cell cycle|multicellular organismal development|spermatogenesis|nervous system development|regulation of actin polymerization or depolymerization|phosphorylation|dendrite development|cell differentiation|intracellular signal transduction|negative regulation of neuron differentiation|generation of neurons|negative regulation of dendrite morphogenesis|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rho GTPase binding|SH3 domain binding|PDZ domain binding|metal ion binding|",10,1.4,7.81,10,0.3,1.79,0.4,6.66,6.66,0.0919,0,0,0.1,2.2
ENSMUSG00000031645,F11,coagulation factor XI,extracellular region|extracellular space|extracellular vesicular exosome|,proteolysis|blood coagulation|hemostasis|regulation of blood coagulation|plasminogen activation|positive regulation of fibrinolysis|,catalytic activity|serine-type endopeptidase activity|heparin binding|peptidase activity|serine-type peptidase activity|hydrolase activity|serine-type aminopeptidase activity|,10,0.3,1.49,10,0.6,6.52,0.5,6.61,6.61,0.0929,0,0,0.1,1.4
ENSMUSG00000069089,CDK7,cyclin-dependent kinase 7,nucleus|nucleus|holo TFIIH complex|cytoplasm|mitochondrion|cytosol|cytoskeleton|membrane|,"ATP catabolic process|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|cell cycle|phosphorylation|positive regulation of transcription from RNA polymerase II promoter|cell division|regulation of cell cycle|regulation of cell cycle|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|protein C-terminus binding|DNA-dependent ATPase activity|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein complex binding|",4,-0.5,2.47,4,-0.5,4.39,-0.5,6.54,-6.54,0.0945,0,0,-1.8,-0.1
ENSMUSG00000017418,ARL5B,ADP-ribosylation factor-like 5B,cellular_component|intracellular|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,1.3,9.57,10,0.1,0.14,1.3,6.53,6.53,0.0947,0,0,0.5,2
ENSMUSG00000028771,PTPN12,"protein tyrosine phosphatase, non-receptor type 12",podosome|cytoplasm|cytosol|plasma membrane|cell junction|cell projection|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|SH3 domain binding|,10,1.6,1.43,10,-0.7,5.59,-0.7,6.53,-6.53,0.0947,0,0,-2,0
ENSMUSG00000001240,RAMP2,receptor (calcitonin) activity modifying protein 2,cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|,angiogenesis|vasculogenesis|sprouting angiogenesis|cAMP biosynthetic process|transport|calcium ion transport|intracellular protein transport|signal transduction|G-protein coupled receptor signaling pathway|heart development|regulation of blood pressure|regulation of G-protein coupled receptor protein signaling pathway|positive regulation of gene expression|positive regulation of gene expression|protein transport|positive regulation of cAMP biosynthetic process|receptor internalization|adherens junction assembly|adherens junction assembly|cellular response to vascular endothelial growth factor stimulus|negative regulation of vascular permeability|negative regulation of vascular permeability|positive regulation of angiogenesis|tight junction assembly|tight junction assembly|basement membrane assembly|protein localization to plasma membrane|vascular smooth muscle cell development|negative regulation of endothelial cell apoptotic process|negative regulation of endothelial cell apoptotic process|positive regulation of vasculogenesis|,protein transporter activity|coreceptor activity|coreceptor activity|,10,0.4,2.2,10,-0.4,5.2,-0.4,6.49,-6.49,0.0956,0,0,-1.3,0.7
ENSMUSG00000035473,GALM,galactose mutarotase,cytoplasm|extracellular vesicular exosome|,carbohydrate metabolic process|glucose metabolic process|galactose metabolic process|hexose metabolic process|,catalytic activity|aldose 1-epimerase activity|isomerase activity|carbohydrate binding|,10,1.5,6.42,10,0.5,3.14,1,6.44,6.44,0.0968,0,0,0.2,2.7
ENSMUSG00000021877,ARF4,ADP-ribosylation factor 4,intracellular|cytoplasm|Golgi apparatus|cytosol|plasma membrane|membrane|ruffle membrane|extracellular vesicular exosome|,protein ADP-ribosylation|transport|epidermal growth factor receptor signaling pathway|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|cell migration|activation of phospholipase D activity|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process|,nucleotide binding|epidermal growth factor receptor binding|protein binding|GTP binding|GTP binding|,10,0.5,3.97,10,0.4,3.01,0.5,6.36,6.36,0.0987,0,0,0,1.2
ENSMUSG00000026437,CDK18,cyclin-dependent kinase 18,None,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.5,4.51,10,-0.8,2.73,-0.5,6.34,-6.34,0.0992,0,0,-1.6,-0.1
ENSMUSG00000031349,NSDHL,NAD(P) dependent steroid dehydrogenase-like,endoplasmic reticulum|lipid particle|membrane|integral component of membrane|intracellular membrane-bounded organelle|,hair follicle development|lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|smoothened signaling pathway|steroid metabolic process|cholesterol metabolic process|sterol biosynthetic process|oxidation-reduction process|labyrinthine layer blood vessel development|,"3-beta-hydroxy-delta5-steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity|",10,0.4,2.28,10,0.8,5.34,0.5,6.32,6.32,0.0997,0,0,0.1,1.5
ENSMUSG00000015291,GDI1,guanosine diphosphate (GDP) dissociation inhibitor 1,cytoplasm|Golgi apparatus|midbody|neuron projection|protein complex|,protein transport|negative regulation of axonogenesis|regulation of catalytic activity|response to calcium ion|negative regulation of protein targeting to membrane|,Rab GDP-dissociation inhibitor activity|GTPase activator activity|Rab GTPase binding|,10,-1.6,9.07,10,0.2,0.867,-0.3,6.3,-6.3,0.1,0,0,-2.9,-0.1
ENSMUSG00000035576,L3MBTL1,l(3)mbt-like (Drosophila),chromatin|condensed chromosome|nucleus|nucleoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of mitosis|chromatin modification|regulation of gene expression, epigenetic|regulation of megakaryocyte differentiation|negative regulation of transcription, DNA-templated|",chromatin binding|sequence-specific DNA binding transcription factor activity|zinc ion binding|nucleosome binding|nucleosomal histone binding|SAM domain binding|methylated histone binding|histone binding|identical protein binding|metal ion binding|,10,-0.4,2.24,10,-0.4,4.33,-0.4,6.27,-6.27,0.101,0,0,-1.2,0.3
ENSMUSG00000039220,PPP1R10,"protein phosphatase 1, regulatory subunit 10",chromatin|nuclear chromatin|nucleus|PTW/PP1 phosphatase complex|,"transcription, DNA-templated|negative regulation of catalytic activity|",DNA binding|RNA binding|protein phosphatase inhibitor activity|protein binding|protein phosphatase 1 binding|poly(A) RNA binding|metal ion binding|,6,0.8,3.66,5,-0.9,4.57,-0.8,6.25,-6.25,0.102,0,0,-2,0.9
ENSMUSG00000062044,LMTK3,lemur tyrosine kinase 3,membrane|integral component of membrane|cell projection|,protein phosphorylation|negative regulation of phosphatase activity|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.1,4.12,10,0.6,2.85,0.6,6.22,6.22,0.102,0,0,0.1,1.8
ENSMUSG00000005102,EIF2AK4,eukaryotic translation initiation factor 2 alpha kinase 4,cytosolic ribosome|,regulation of translational initiation|protein phosphorylation|cellular response to starvation|phosphorylation|negative regulation of translation|endoplasmic reticulum unfolded protein response|regulation of translational initiation in response to stress|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|",10,1.2,6.04,10,0.4,2.86,0.8,6.2,6.2,0.103,0,0,0.2,1.9
ENSMUSG00000031090,NADSYN1,NAD synthetase 1,cytoplasm|,nitrogen compound metabolic process|NAD biosynthetic process|,"nucleotide binding|NAD+ synthase (glutamine-hydrolyzing) activity|ATP binding|NAD+ synthase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|ligase activity|",10,1.1,3.05,10,0.5,4.49,0.5,6.18,6.18,0.104,0,0,0.1,1.7
ENSMUSG00000059734,NDUFS8,NADH dehydrogenase (ubiquinone) Fe-S protein 8,mitochondrion|mitochondrion|mitochondrial respiratory chain complex I|membrane|respiratory chain|,transport|response to oxidative stress|mitochondrial respiratory chain complex I assembly|oxidation-reduction process|,"NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",8,1,5.36,7,0.3,2.28,0.5,6.08,6.08,0.106,0,0,-0.1,2
ENSMUSG00000030802,BCKDK,branched chain ketoacid dehydrogenase kinase,mitochondrion|mitochondrion|mitochondrial alpha-ketoglutarate dehydrogenase complex|,protein phosphorylation|branched-chain amino acid catabolic process|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity|",10,0.1,0.531,10,1.1,7.88,1.1,6.06,6.06,0.107,0,0,0.2,1.9
ENSMUSG00000028690,MMACHC,"methylmalonic aciduria cblC type, with homocystinuria",cytoplasm|mitochondrion|,biological_process|,molecular_function|cobalamin binding|,7,0.9,6.77,5,-0.6,5.44,-0.7,6.01,-6.01,0.108,0,0,-2,1.4
ENSMUSG00000029596,SDSL,serine dehydratase-like,mitochondrion|extracellular vesicular exosome|,biological_process|,molecular_function|L-serine ammonia-lyase activity|L-threonine ammonia-lyase activity|lyase activity|,9,0.8,8.86,9,-0.4,3.17,0.8,5.98,5.98,0.109,0,0,-0.6,2
ENSMUSG00000022820,NDUFB4,NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|nuclear membrane|extracellular vesicular exosome|,response to oxidative stress|,molecular_function|,10,0.9,0.326,9,0.6,6.09,0.6,5.97,5.97,0.109,0,0,0.1,1.7
ENSMUSG00000007589,TINF2,Terf1 (TRF1)-interacting nuclear factor 2,"chromosome, telomeric region|chromosome, telomeric region|nuclear telomere cap complex|nucleus|chromosome|perinucleolar chromocenter|","telomere maintenance via telomere lengthening|negative regulation of protein ADP-ribosylation|telomere assembly|negative regulation of telomere maintenance|positive regulation of telomere maintenance|negative regulation of telomere maintenance via telomerase|protein localization to chromosome|negative regulation of epithelial cell proliferation|protein localization to chromosome, telomeric region|",protein binding|telomeric DNA binding|,2,1.2,6.08,2,0.4,0.954,1.1,5.91,5.91,0.111,0,0,0.1,2
ENSMUSG00000027784,PPM1L,protein phosphatase 1 (formerly 2C)-like,intracellular|membrane|integral component of membrane|extracellular vesicular exosome|,MAPK cascade|protein dephosphorylation|transmembrane receptor protein serine/threonine kinase signaling pathway|dephosphorylation|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein binding|hydrolase activity|metal ion binding|,10,0.9,2.14,10,0.9,4.04,0.9,5.88,5.88,0.112,0,0,0.2,2
ENSMUSG00000096146,KCNJ11,"potassium inwardly rectifying channel, subfamily J, member 11",nuclear envelope|mitochondrion|endosome|endoplasmic reticulum|cytosol|plasma membrane|plasma membrane|voltage-gated potassium channel complex|ATP-sensitive potassium channel complex|ATP-sensitive potassium channel complex|intercalated disc|membrane|integral component of membrane|T-tubule|T-tubule|axolemma|sarcolemma|neuronal cell body|myelin sheath|intracellular membrane-bounded organelle|cell body fiber|,glucose metabolic process|transport|ion transport|potassium ion transport|potassium ion import|response to ATP|regulation of ion transmembrane transport|regulation of membrane potential|response to drug|negative regulation of insulin secretion|regulation of insulin secretion|neurological system process|potassium ion transmembrane transport|positive regulation of cation channel activity|,inward rectifier potassium channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|protein binding|ATP binding|protein C-terminus binding|ATP-activated inward rectifier potassium channel activity|ATP-activated inward rectifier potassium channel activity|ankyrin binding|ankyrin binding|potassium ion binding|heat shock protein binding|ion channel binding|,10,0.3,1.68,10,0.5,4.63,0.5,5.82,5.82,0.114,0,0,0,1.3
ENSMUSG00000020899,PFAS,phosphoribosylformylglycinamidine synthase (FGAR amidotransferase),cytoplasm|extracellular vesicular exosome|,purine nucleotide biosynthetic process|'de novo' IMP biosynthetic process|glutamine metabolic process|ribonucleoside monophosphate biosynthetic process|,nucleotide binding|catalytic activity|phosphoribosylformylglycinamidine synthase activity|ATP binding|ligase activity|,8,1.3,8,8,0.2,0.823,1.2,5.75,5.75,0.116,0,0,-2.3,2
ENSMUSG00000026450,CHIT1,chitinase 1 (chitotriosidase),extracellular region|extracellular space|lysosome|,polysaccharide catabolic process|carbohydrate metabolic process|chitin metabolic process|chitin catabolic process|metabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|chitinase activity|chitin binding|endochitinase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.2,0.816,10,0.5,5.91,0.5,5.73,5.73,0.116,0,0,0,1.5
ENSMUSG00000000276,DGKE,"diacylglycerol kinase, epsilon",cytoplasm|membrane|integral component of membrane|,protein kinase C-activating G-protein coupled receptor signaling pathway|metabolic process|phosphorylation|intracellular signal transduction|,nucleotide binding|NAD+ kinase activity|diacylglycerol kinase activity|ATP binding|kinase activity|transferase activity|metal ion binding|,10,0.3,1.3,10,0.4,4.67,0.4,5.7,5.7,0.117,0,0,0,1.3
ENSMUSG00000032040,DCPS,"decapping enzyme, scavenger",nucleus|cytoplasm|mitochondrion|,"deadenylation-dependent decapping of nuclear-transcribed mRNA|mRNA processing|RNA splicing|cellular response to menadione|negative regulation of programmed cell death|mRNA cis splicing, via spliceosome|",RNA 7-methylguanosine cap binding|catalytic activity|hydrolase activity|m7G(5')pppN diphosphatase activity|,10,1.4,8.19,10,0.1,0.619,0.6,5.68,5.68,0.118,0,0,0.1,2.5
ENSMUSG00000041881,NDUFA7,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain|,transport|biological_process|ATP synthesis coupled electron transport|oxidation-reduction process|,molecular_function|NADH dehydrogenase (ubiquinone) activity|,10,0.9,4.08,10,-1,2.75,0.6,5.67,5.67,0.118,0,0,-1,1.9
ENSMUSG00000027968,LARP7,"La ribonucleoprotein domain family, member 7",nucleus|cytoplasm|Golgi apparatus|ribonucleoprotein complex|,negative regulation of transcription from RNA polymerase II promoter|RNA processing|negative regulation of chromatin binding|germ cell proliferation|positive regulation of G1/S transition of mitotic cell cycle|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.3,0.751,10,0.5,5.57,0.5,5.65,5.65,0.119,0,0,-0.2,1.4
ENSMUSG00000026246,ALPPL2,"alkaline phosphatase, placental-like 2",plasma membrane|membrane|myofibril|anchored component of membrane|,metabolic process|dephosphorylation|,catalytic activity|alkaline phosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|,9,0.2,1.78,9,0.7,5.28,0.6,5.64,5.64,0.119,0,0,0,1.6
ENSMUSG00000052456,ASNA1,"arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)",nucleus|nucleolus|cytoplasm|endoplasmic reticulum|extracellular vesicular exosome|,transport|,nucleotide binding|ATP binding|hydrolase activity|ATPase activity|metal ion binding|,6,0.5,4.8,7,0.4,1.06,0.5,5.55,5.55,0.123,0,0,-0.1,1.7
ENSMUSG00000024969,MARK2,MAP/microtubule affinity-regulating kinase 2,nucleus|cytoplasm|cytoskeleton|actin filament|plasma membrane|membrane|lateral plasma membrane|basal cortex|microtubule bundle|,neuron migration|protein phosphorylation|multicellular organismal development|positive regulation of neuron projection development|Wnt signaling pathway|phosphorylation|establishment of cell polarity|cell differentiation|intracellular signal transduction|establishment or maintenance of epithelial cell apical/basal polarity|protein autophosphorylation|regulation of axonogenesis|regulation of cytoskeleton organization|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|metal ion binding|tau-protein kinase activity|",10,-0.3,1.61,10,-0.4,4.29,-0.4,5.55,-5.55,0.123,0,0,-1.2,0
ENSMUSG00000020405,FABP6,"fatty acid binding protein 6, ileal (gastrotropin)",cytoplasm|cytosol|,transport|bile acid metabolic process|,transporter activity|fatty acid binding|lipid binding|,10,0.8,4.01,10,0.7,1.8,0.7,5.52,5.52,0.124,0,0,0.1,1.8
ENSMUSG00000043733,PTPN11,"protein tyrosine phosphatase, non-receptor type 11",stress fiber|nucleus|cytoplasm|mitochondrion|cytosol|membrane|cell junction|protein complex|,DNA damage checkpoint|activation of MAPK activity|protein dephosphorylation|lipid metabolic process|triglyceride metabolic process|epidermal growth factor receptor signaling pathway|integrin-mediated signaling pathway|axonogenesis|brain development|heart development|hormone-mediated signaling pathway|positive regulation of signal transduction|positive regulation of signal transduction|dephosphorylation|platelet formation|abortive mitotic cell cycle|regulation of cell adhesion mediated by integrin|negative regulation of cell adhesion mediated by integrin|organ growth|peptidyl-tyrosine dephosphorylation|megakaryocyte development|atrioventricular canal development|ERBB signaling pathway|regulation of multicellular organism growth|hormone metabolic process|glucose homeostasis|negative regulation of insulin secretion|regulation of protein export from nucleus|positive regulation of hormone secretion|negative regulation of hormone secretion|platelet-derived growth factor receptor signaling pathway|neurotrophin TRK receptor signaling pathway|ephrin receptor signaling pathway|multicellular organismal reproductive process|genitalia development|inner ear development|negative regulation of cortisol secretion|negative regulation of growth hormone secretion|face morphogenesis|positive regulation of ERK1 and ERK2 cascade|positive regulation of glucose import in response to insulin stimulus|,phosphoprotein phosphatase activity|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|non-membrane spanning protein tyrosine phosphatase activity|SH3/SH2 adaptor activity|insulin receptor binding|protein binding|hydrolase activity|phosphatase activity|protein domain specific binding|receptor tyrosine kinase binding|D1 dopamine receptor binding|phospholipase binding|insulin receptor substrate binding|peptide hormone receptor binding|,4,-1,5.84,3,-0.3,0.695,-0.9,5.39,-5.39,0.128,0,0,-2,0.4
ENSMUSG00000015405,ACE2,angiotensin I converting enzyme (peptidyl-dipeptidase A) 2,extracellular region|extracellular space|plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,angiotensin-mediated drinking behavior|regulation of systemic arterial blood pressure by renin-angiotensin|proteolysis|proteolysis|response to virus|receptor biosynthetic process|receptor-mediated virion attachment to host cell|,virus receptor activity|glycoprotein binding|endopeptidase activity|carboxypeptidase activity|carboxypeptidase activity|peptidase activity|metallopeptidase activity|peptidyl-dipeptidase activity|hydrolase activity|peptide hormone binding|peptide binding|metal ion binding|,10,-0.8,3.69,10,-0.9,2.05,-0.8,5.33,-5.33,0.13,0,0,-2,0.3
ENSMUSG00000041841,RPL37,ribosomal protein L37,cytosolic large ribosomal subunit|,None,molecular_function|,3,0.3,0.124,3,0.6,5.8,0.5,5.31,5.31,0.131,0,0,0,2
ENSMUSG00000072664,UGT3A1,"UDP glycosyltransferases 3 family, polypeptide A1",membrane|integral component of membrane|UDP-N-acetylglucosamine transferase complex|,metabolic process|cellular response to genistein|,"UDP-glycosyltransferase activity|UDP-glycosyltransferase activity|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,-0.4,3.66,10,-0.3,2.13,-0.4,5.3,-5.3,0.132,0,0,-1.1,0.1
ENSMUSG00000015994,FNTA,"farnesyltransferase, CAAX box, alpha",cytoplasm|microtubule associated complex|CAAX-protein geranylgeranyltransferase complex|protein farnesyltransferase complex|,positive regulation of cell proliferation|response to inorganic substance|regulation of receptor activity|response to organic cyclic compound|protein prenylation|protein farnesylation|protein geranylgeranylation|response to cytokine|negative regulation of apoptotic process|neurotransmitter receptor metabolic process|positive regulation of cell cycle|positive regulation of nitric-oxide synthase biosynthetic process|negative regulation of nitric-oxide synthase biosynthetic process|positive regulation of tubulin deacetylation|positive regulation of deacetylase activity|,prenyltransferase activity|protein farnesyltransferase activity|protein farnesyltransferase activity|protein farnesyltransferase activity|protein geranylgeranyltransferase activity|CAAX-protein geranylgeranyltransferase activity|Rab geranylgeranyltransferase activity|microtubule binding|drug binding|zinc ion binding|protein prenyltransferase activity|transferase activity|isoprenoid binding|acetylcholine receptor regulator activity|receptor tyrosine kinase binding|peptide binding|alpha-tubulin binding|,10,0.9,0.683,9,0.4,5.25,0.4,5.28,5.28,0.132,0,0,-0.1,1.6
ENSMUSG00000029231,PDGFRA,"platelet derived growth factor receptor, alpha polypeptide",nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|integral component of plasma membrane|microvillus|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|intrinsic component of plasma membrane|,luteinization|luteinization|in utero embryonic development|hematopoietic progenitor cell differentiation|protein phosphorylation|chemotaxis|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of cytosolic calcium ion concentration|multicellular organismal development|estrogen metabolic process|positive regulation of cell proliferation|female gonad development|anatomical structure morphogenesis|organ morphogenesis|negative regulation of platelet activation|positive regulation of phospholipase C activity|phosphorylation|cell migration|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|signal transduction involved in regulation of gene expression|extracellular matrix organization|lung development|adrenal gland development|positive regulation of cell migration|male genitalia development|Leydig cell differentiation|platelet-derived growth factor receptor-alpha signaling pathway|platelet-derived growth factor receptor-alpha signaling pathway|cellular response to platelet-derived growth factor stimulus|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway|wound healing|odontogenesis of dentin-containing tooth|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of DNA replication|protein autophosphorylation|protein autophosphorylation|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of fibroblast proliferation|embryonic digestive tract morphogenesis|embryonic cranial skeleton morphogenesis|skeletal system morphogenesis|regulation of chemotaxis|cardiac myofibril assembly|palate development|face morphogenesis|cell chemotaxis|cell chemotaxis|retina vasculature development in camera-type eye|positive regulation of ERK1 and ERK2 cascade|platelet aggregation|cellular response to amino acid stimulus|metanephric glomerular capillary formation|regulation of mesenchymal stem cell differentiation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|platelet-derived growth factor alpha-receptor activity|platelet-derived growth factor alpha-receptor activity|vascular endothelial growth factor-activated receptor activity|platelet-derived growth factor receptor binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|vascular endothelial growth factor binding|protein homodimerization activity|phosphatidylinositol 3-kinase binding|platelet-derived growth factor binding|platelet-derived growth factor binding|platelet-derived growth factor binding|",10,0.5,3.95,10,0.4,1.68,0.5,5.28,5.28,0.132,0,0,-0.4,1.3
ENSMUSG00000093930,HMGCS1,3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1,nucleus|cytoplasm|cytosol|plasma membrane|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|metabolic process|steroid metabolic process|cholesterol metabolic process|isoprenoid biosynthetic process|response to organonitrogen compound|sterol biosynthetic process|,catalytic activity|hydroxymethylglutaryl-CoA synthase activity|drug binding|transferase activity|isomerase activity|protein homodimerization activity|organic acid binding|,6,0.8,4.23,5,0.5,1.53,0.7,5.26,5.26,0.133,0,0,-0.3,2
ENSMUSG00000008730,HIPK1,homeodomain interacting protein kinase 1,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|PML body|nuclear speck|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|smoothened signaling pathway|positive regulation of cell proliferation|anterior/posterior pattern specification|regulation of tumor necrosis factor-mediated signaling pathway|retina layer formation|phosphorylation|protein desumoylation|neuron differentiation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of DNA binding|embryonic camera-type eye morphogenesis|embryonic retina morphogenesis in camera-type eye|lens induction in camera-type eye|iris morphogenesis|endothelial cell apoptotic process|extrinsic apoptotic signaling pathway|","nucleotide binding|transcription corepressor activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.3,1.72,10,-0.5,4.11,-0.5,5.25,-5.25,0.133,0,0,-1.3,0.1
ENSMUSG00000020936,NMT1,N-myristoyltransferase 1,cytoplasm|cytoplasm|plasma membrane|actin cytoskeleton|cell junction|,in utero embryonic development|N-terminal protein myristoylation|N-terminal peptidyl-glycine N-myristoylation|,"glycylpeptide N-tetradecanoyltransferase activity|glycylpeptide N-tetradecanoyltransferase activity|glycylpeptide N-tetradecanoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|myristoyltransferase activity|",9,-0.5,0.623,8,-0.6,4.9,-0.5,5.23,-5.23,0.134,0,0,-1.6,0.1
ENSMUSG00000003585,SEC14L2,SEC14-like 2 (S. cerevisiae),intracellular|nucleus|cytoplasm|cytosol|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|positive regulation of catalytic activity|positive regulation of cholesterol biosynthetic process|","transporter activity|enzyme activator activity|lipid binding|transferase activity, transferring alkyl or aryl (other than methyl) groups|",10,-0.5,4.2,10,-0.5,1.29,-0.5,5.23,-5.23,0.134,0,0,-1.4,0.2
ENSMUSG00000030946,LHPP,phospholysine phosphohistidine inorganic pyrophosphate phosphatase,nucleus|cytoplasm|cytosol|,phosphate-containing compound metabolic process|,"inorganic diphosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|protein homodimerization activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|metal ion binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0,0,10,-0.8,7.43,-0.7,5.14,-5.14,0.137,0,0,-1.9,0
ENSMUSG00000038486,SV2A,synaptic vesicle glycoprotein 2 a,cytoplasm|endoplasmic reticulum|cell-cell junction|synaptic vesicle|membrane|integral component of membrane|cell junction|synaptic vesicle membrane|cytoplasmic vesicle|neuromuscular junction|neuron projection|synapse|presynaptic active zone|,transport|neurotransmitter transport|cellular calcium ion homeostasis|synaptic transmission|transmembrane transport|,receptor activity|transporter activity|transmembrane transporter activity|,10,0.6,5.26,10,0.5,0.163,0.6,5.14,5.14,0.137,0,0,0,1.8
ENSMUSG00000026023,CDK15,cyclin-dependent kinase 15,cellular_component|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.4,1.63,10,0.9,4.25,0.9,5.04,5.04,0.141,0,0,0.1,1.9
ENSMUSG00000024085,MAN2A1,"mannosidase 2, alpha 1",Golgi membrane|Golgi apparatus|cis-Golgi network|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,in utero embryonic development|liver development|carbohydrate metabolic process|mannose metabolic process|N-glycan processing|mitochondrion organization|vacuole organization|respiratory gaseous exchange|metabolic process|lung alveolus development|positive regulation of neurogenesis|retina morphogenesis in camera-type eye|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity|zinc ion binding|mannosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hydrolase activity, hydrolyzing N-glycosyl compounds|carbohydrate binding|metal ion binding|",10,0.7,7.67,10,0,0,0.5,5.01,5.01,0.142,0,0,0,1.6
ENSMUSG00000067279,PPP1R3C,"protein phosphatase 1, regulatory (inhibitor) subunit 3C",intracellular|cell|glycogen granule|intracellular membrane-bounded organelle|,carbohydrate metabolic process|glycogen metabolic process|glycogen biosynthetic process|protein targeting|,phosphoprotein phosphatase activity|enzyme binding|protein phosphatase binding|,10,1,8.21,10,0,0,1,5,5,0.143,0,0,0.2,2
ENSMUSG00000024712,RFK,riboflavin kinase,cytoplasm|mitochondrion|,apoptotic process|riboflavin biosynthetic process|phosphorylation|positive regulation of NAD(P)H oxidase activity|positive regulation of NAD(P)H oxidase activity|reactive oxygen species metabolic process|,nucleotide binding|protein binding|ATP binding|riboflavin kinase activity|kinase activity|transferase activity|metal ion binding|,8,-1,5.74,7,0.4,4.03,-0.9,4.99,-4.99,0.143,0,0,-2,0.6
ENSMUSG00000027379,BUB1,budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae),"chromosome, centromeric region|kinetochore|kinetochore|condensed chromosome kinetochore|condensed nuclear chromosome, centromeric region|nucleus|chromosome|cytoplasm|membrane|",protein phosphorylation|apoptotic process|cell cycle|chromosome segregation|regulation of sister chromatid cohesion|mitotic nuclear division|embryo development|phosphorylation|cell division|regulation of chromosome segregation|spindle assembly checkpoint|spindle assembly checkpoint|mitotic spindle checkpoint|positive regulation of intrinsic apoptotic signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,1.4,7.91,10,-0.1,0.0526,1.4,4.93,4.93,0.146,0,0,0,3
ENSMUSG00000037851,IARS,isoleucine-tRNA synthetase,cytoplasm|membrane|extracellular vesicular exosome|,osteoblast differentiation|translation|tRNA aminoacylation for protein translation|isoleucyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA editing activity|aminoacyl-tRNA ligase activity|isoleucine-tRNA ligase activity|ATP binding|ligase activity|,6,0.5,3.15,7,0.4,2.09,0.5,4.92,4.92,0.146,0,0,-0.5,1.7
ENSMUSG00000056076,EIF3B,"eukaryotic translation initiation factor 3, subunit B","cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|extracellular vesicular exosome|eukaryotic translation initiation factor 3 complex, eIF3m|",translation|translational initiation|translational initiation|regulation of translational initiation|,nucleotide binding|nucleic acid binding|RNA binding|translation initiation factor activity|translation initiation factor activity|translation initiation factor activity|protein binding|translation initiation factor binding|,3,-1,5.98,2,0,0,-1,4.73,-4.73,0.154,0,0,-2,0.1
ENSMUSG00000021428,RIOK1,RIO kinase 1 (yeast),cellular_component|,phosphorylation|,"nucleotide binding|catalytic activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",8,1.5,5.05,8,-0.9,3.33,1.4,4.69,4.69,0.155,0,0,-1.1,3
ENSMUSG00000029776,HIBADH,3-hydroxyisobutyrate dehydrogenase,mitochondrion|,pentose-phosphate shunt|valine metabolic process|valine catabolic process|branched-chain amino acid catabolic process|oxidation-reduction process|,"phosphogluconate dehydrogenase (decarboxylating) activity|3-hydroxyisobutyrate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|coenzyme binding|NAD binding|",10,0.1,0.169,10,0.5,5.95,0.4,4.63,4.63,0.158,0,0,-0.2,1.4
ENSMUSG00000005683,CS,citrate synthase,nucleus|mitochondrion|mitochondrion|mitochondrion|mitochondrial matrix|extracellular vesicular exosome|,carbohydrate metabolic process|acetyl-CoA metabolic process|tricarboxylic acid cycle|citrate metabolic process|oxaloacetate metabolic process|cellular carbohydrate metabolic process|,"citrate (Si)-synthase activity|citrate (Si)-synthase activity|transferase activity|poly(A) RNA binding|transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer|",10,0.5,1.91,10,-0.9,3.74,0.6,4.59,4.59,0.16,0,0,-1.5,1.6
ENSMUSG00000014956,PPP1CB,"protein phosphatase 1, catalytic subunit, beta isoform",protein phosphatase type 1 complex|nucleus|cytoplasm|glycogen granule|extracellular vesicular exosome|MLL5-L complex|PTW/PP1 phosphatase complex|,carbohydrate metabolic process|glycogen metabolic process|regulation of glycogen biosynthetic process|regulation of glycogen catabolic process|protein dephosphorylation|protein dephosphorylation|cell cycle|regulation of cell adhesion|circadian regulation of gene expression|regulation of circadian rhythm|regulation of circadian rhythm|regulation of circadian rhythm|entrainment of circadian clock by photoperiod|rhythmic process|cell division|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|protein kinase binding|metal ion binding|myosin-light-chain-phosphatase activity|,7,-0.8,1.81,6,-0.7,3.04,-0.7,4.53,-4.53,0.163,0,0,-2,0.8
ENSMUSG00000026401,DAF2,decay accelerating factor 2,plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|membrane raft|extracellular vesicular exosome|,"immune system process|complement activation, classical pathway|response to virus|negative regulation of catalytic activity|innate immune response|",virus receptor activity|enzyme inhibitor activity|lipid binding|,10,1.2,2.32,10,0.5,4.48,0.6,4.52,4.52,0.163,0,0,-0.1,2
ENSMUSG00000032570,ATP2C1,"ATPase, Ca++-sequestering",Golgi membrane|Golgi apparatus|trans-Golgi network|plasma membrane|membrane|membrane|integral component of membrane|transport vesicle|secretory granule|intracellular membrane-bounded organelle|,ATP catabolic process|transport|ion transport|cation transport|calcium ion transport|manganese ion transport|cellular calcium ion homeostasis|signal transduction|epidermis development|calcium-dependent cell-cell adhesion|cellular manganese ion homeostasis|actin cytoskeleton reorganization|Golgi calcium ion homeostasis|Golgi calcium ion transport|positive regulation of I-kappaB kinase/NF-kappaB signaling|calcium ion transmembrane transport|calcium ion transmembrane transport|manganese ion transmembrane transport|,nucleotide binding|signal transducer activity|calcium-transporting ATPase activity|calcium-transporting ATPase activity|calcium ion binding|ATP binding|manganese-transporting ATPase activity|hydrolase activity|cation-transporting ATPase activity|manganese ion binding|metal ion binding|,9,0.6,3.59,9,0.3,1.79,0.4,4.5,4.5,0.164,0,0,-0.1,1.5
ENSMUSG00000035429,PTPRH,"protein tyrosine phosphatase, receptor type, H",None,None,phosphoprotein phosphatase activity|hydrolase activity|,10,-0.4,1.73,10,0.4,4.56,-0.6,4.48,-4.48,0.165,0,0,-2,0.6
ENSMUSG00000031138,F9,coagulation factor IX,extracellular region|,proteolysis|blood coagulation|blood coagulation|hemostasis|,catalytic activity|serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,1.3,3.78,10,1,1.3,1.2,4.45,4.45,0.167,0,0,-0.1,2
ENSMUSG00000035283,ADRB1,"adrenergic receptor, beta 1",nucleus|cytoplasm|endosome|early endosome|plasma membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,positive regulation of heart rate by epinephrine-norepinephrine|positive regulation of the force of heart contraction by epinephrine-norepinephrine|positive regulation of the force of heart contraction by epinephrine-norepinephrine|diet induced thermogenesis|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|positive regulation of the force of heart contraction by norepinephrine|positive regulation of systemic arterial blood pressure|glycogen catabolic process|apoptotic process|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|Rho protein signal transduction|memory|response to cold|positive regulation of heart rate|sensory perception of pain|positive regulation of cAMP biosynthetic process|heat generation|positive regulation of Ras GTPase activity|protein localization to organelle|negative regulation of urine volume|negative regulation of multicellular organism growth|wound healing|fear response|positive regulation of apoptotic process|positive regulation of cAMP-mediated signaling|positive regulation of adenylate cyclase activity|positive regulation of heart contraction|negative regulation of smooth muscle contraction|positive regulation of saliva secretion|brown fat cell differentiation|regulation of calcium ion transport|lipid homeostasis|regulation of inhibitory postsynaptic membrane potential|positive regulation of cell growth involved in cardiac muscle cell development|adrenergic receptor signaling pathway|adenylate cyclase-activating adrenergic receptor signaling pathway|regulation of cardiac muscle cell contraction|positive regulation of renin secretion into blood stream|positive regulation of long-term synaptic potentiation|positive regulation of cation channel activity|,signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|beta1-adrenergic receptor activity|beta1-adrenergic receptor activity|beta1-adrenergic receptor activity|receptor signaling protein activity|Ras guanyl-nucleotide exchange factor activity|protein binding|drug binding|PDZ domain binding|alpha-2A adrenergic receptor binding|dopamine binding|protein heterodimerization activity|epinephrine binding|norepinephrine binding|,10,1.7,3.6,10,0.8,3.21,1.6,4.4,4.4,0.169,0,0,0.1,2.7
ENSMUSG00000032290,PTPN9,"protein tyrosine phosphatase, non-receptor type 9",cytoplasm|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,10,0.5,6.28,10,-0.1,0.288,0.5,4.4,4.4,0.169,0,0,-0.2,1.5
ENSMUSG00000068748,PTPRZ1,"protein tyrosine phosphatase, receptor type Z, polypeptide 1",extracellular region|proteinaceous extracellular matrix|plasma membrane|membrane|integral component of membrane|perineuronal net|,hematopoietic progenitor cell differentiation|protein dephosphorylation|axonogenesis|learning or memory|dephosphorylation|peptidyl-tyrosine dephosphorylation|oligodendrocyte differentiation|regulation of oligodendrocyte progenitor proliferation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,10,-0.5,1.54,10,-0.6,3.07,-0.5,4.33,-4.33,0.173,0,0,-1.5,0.3
ENSMUSG00000000278,SCPEP1,serine carboxypeptidase 1,extracellular region|cytosol|extracellular vesicular exosome|,proteolysis|,carboxypeptidase activity|serine-type carboxypeptidase activity|peptidase activity|hydrolase activity|,9,0.4,1.59,9,1.6,5.68,1.5,4.29,4.29,0.175,0,0,0.1,3
ENSMUSG00000027475,KIF3B,kinesin family member 3B,cytoplasm|centrosome|spindle|cytoskeleton|kinesin complex|microtubule|cilium|microtubule cytoskeleton|membrane|kinesin II complex|kinesin II complex|midbody|intraciliary transport particle|extracellular vesicular exosome|,microtubule-based movement|positive regulation of cytokinesis|spindle assembly involved in mitosis|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|Rho GTPase binding|,10,0.6,3.05,10,0.3,1.67,0.4,4.26,4.26,0.176,0,0,-0.4,1.4
ENSMUSG00000037754,PPP1R16B,"protein phosphatase 1, regulatory (inhibitor) subunit 16B",nucleus|plasma membrane|membrane|,None,None,10,1,7.45,10,-0.2,2.33,0.8,4.24,4.24,0.177,0,0,-0.2,2
ENSMUSG00000037926,SSH2,slingshot homolog 2 (Drosophila),extracellular space|cytoplasm|cytoskeleton|cell junction|,protein dephosphorylation|protein dephosphorylation|regulation of actin polymerization or depolymerization|regulation of lamellipodium assembly|dephosphorylation|actin cytoskeleton organization|regulation of axonogenesis|,DNA binding|actin binding|actin binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,9,0.5,3.91,9,0.2,1.46,0.4,4.22,4.22,0.178,0,0,-0.2,1.3
ENSMUSG00000025934,GSTA3,"glutathione S-transferase, alpha 3",cytoplasm|,metabolic process|aflatoxin catabolic process|,glutathione transferase activity|transferase activity|,10,0.3,0.721,10,0.6,4.52,0.5,4.21,4.21,0.179,0,0,-0.3,1.7
ENSMUSG00000024290,ROCK1,Rho-associated coiled-coil containing protein kinase 1,ruffle|intracellular|cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|membrane|lamellipodium|cell projection|,apical constriction|protein phosphorylation|apoptotic process|cytoskeleton organization|leukocyte cell-cell adhesion|signal transduction|Rho protein signal transduction|phosphorylation|negative regulation of angiogenesis|membrane to membrane docking|actin cytoskeleton organization|bleb assembly|regulation of actin filament-based process|intracellular signal transduction|negative regulation of neuron apoptotic process|regulation of keratinocyte differentiation|leukocyte migration|leukocyte tethering or rolling|myoblast migration|positive regulation of focal adhesion assembly|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rho GTPase binding|GTP-Rho binding|metal ion binding|",10,-0.5,3.86,10,-0.3,0.903,-0.4,4.21,-4.21,0.179,0,0,-1.5,0.5
ENSMUSG00000023908,PKMYT1,"protein kinase, membrane associated tyrosine/threonine 1",nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|membrane|,protein phosphorylation|cell cycle|negative regulation of phosphatase activity|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.7,5.84,10,0.1,0.553,0.5,4.17,4.17,0.181,0,0,-0.4,1.7
ENSMUSG00000070810,SULT2A6,"sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6",cellular_component|cytoplasm|cytosol|,biological_process|,alcohol sulfotransferase activity|drug binding|sulfotransferase activity|transferase activity|3'-phosphoadenosine 5'-phosphosulfate binding|,10,0.1,0.257,10,-0.8,4.58,-0.7,4.16,-4.16,0.182,0,0,-1.8,0.7
ENSMUSG00000015671,PSMA2,"proteasome (prosome, macropain) subunit, alpha type 2","proteasome complex|cytoplasmic mRNA processing body|nucleus|cytoplasm|proteasome core complex|proteasome core complex, alpha-subunit complex|extracellular vesicular exosome|",proteolysis|ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,3,-0.6,4.85,3,-0.1,0.291,-0.5,4.16,-4.16,0.182,0,0,-2,0.2
ENSMUSG00000023832,ACAT2,acetyl-Coenzyme A acetyltransferase 2,nucleus|nucleolus|cytoplasm|mitochondrion|cytosol|,metabolic process|,"catalytic activity|acetyl-CoA C-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|",10,0.1,0.24,10,0.8,6.26,0.7,4.13,4.13,0.183,0,0,0,1.7
ENSMUSG00000035390,BRSK1,BR serine/threonine kinase 1,nucleus|cytoplasm|centrosome|cytoskeleton|plasma membrane|synaptic vesicle|cell junction|synapse|,G2/M transition of mitotic cell cycle|protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|cell cycle|neurotransmitter secretion|nervous system development|axonogenesis|response to UV|phosphorylation|peptidyl-serine phosphorylation|establishment of cell polarity|establishment of cell polarity|neuron differentiation|G2 DNA damage checkpoint|neuron projection morphogenesis|centrosome duplication|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|gamma-tubulin binding|metal ion binding|tau-protein kinase activity|tau-protein kinase activity|tau-protein kinase activity|",10,1.2,4.79,10,0.3,0.733,0.4,4.11,4.11,0.185,0,0,0,2
ENSMUSG00000019873,REEP3,receptor accessory protein 3,cellular_component|endoplasmic reticulum|microtubule|membrane|integral component of membrane|,nuclear envelope organization|cell cycle|mitotic nuclear division|mitotic nuclear envelope reassembly|cell division|,molecular_function|,10,1.8,7.19,10,-0.2,0.522,1.8,4.09,4.09,0.186,0,0,0.1,3
ENSMUSG00000034290,NEK9,NIMA (never in mitosis gene a)-related expressed kinase 9,nucleus|cytoplasm|,protein phosphorylation|cell cycle|mitotic nuclear division|phosphorylation|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|metal ion binding|",10,-0.2,0.717,10,-0.9,4.8,-0.5,4.07,-4.07,0.187,0,0,-1.8,0.1
ENSMUSG00000042834,NREP,neuronal regeneration related protein,nucleus|cytoplasm|,regulation of transforming growth factor beta receptor signaling pathway|regulation of neuron differentiation|,protein binding|,10,1,1.47,10,-0.6,6.73,-0.6,4.02,-4.02,0.189,0,0,-1.7,1.1
ENSMUSG00000022812,GSK3B,glycogen synthase kinase 3 beta,nucleus|nucleus|cytoplasm|centrosome|cytosol|cytosol|plasma membrane|membrane|growth cone|ribonucleoprotein complex|beta-catenin destruction complex|beta-catenin destruction complex|neuronal cell body|dendritic spine|dendritic shaft|membrane-bounded organelle|protein complex|cell body|membrane raft|perinuclear region of cytoplasm|,re-entry into mitotic cell cycle|epithelial to mesenchymal transition|positive regulation of cell-matrix adhesion|carbohydrate metabolic process|glycogen metabolic process|regulation of gene expression by genetic imprinting|protein phosphorylation|protein phosphorylation|protein phosphorylation|protein phosphorylation|protein phosphorylation|protein export from nucleus|ER overload response|ER overload response|cytoskeleton organization|establishment or maintenance of cell polarity|multicellular organismal development|nervous system development|axonogenesis|myoblast fusion|myoblast fusion|circadian rhythm|cell proliferation|organ morphogenesis|negative regulation of signal transduction|negative regulation of cardiac muscle hypertrophy|positive regulation of peptidyl-threonine phosphorylation|negative regulation of neuron projection development|negative regulation of neuron projection development|negative regulation of neuron maturation|myotube differentiation|Wnt signaling pathway|phosphorylation|cell migration|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|hippocampus development|establishment of cell polarity|cell differentiation|negative regulation of protein complex assembly|positive regulation of protein complex assembly|negative regulation of protein binding|positive regulation of protein binding|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of Rac GTPase activity|regulation of microtubule-based process|regulation of microtubule-based process|positive regulation of peptidyl-serine phosphorylation|protein localization to microtubule|intracellular signal transduction|cellular response to interleukin-3|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of MAP kinase activity|hypermethylation of CpG island|canonical Wnt signaling pathway involved in positive regulation of apoptotic process|fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein export from nucleus|regulation of neuronal synaptic plasticity|rhythmic process|negative regulation of dendrite morphogenesis|negative regulation of NFAT protein import into nucleus|canonical Wnt signaling pathway|canonical Wnt signaling pathway|superior temporal gyrus development|cellular response to mechanical stimulus|extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|positive regulation of stem cell differentiation|,"nucleotide binding|RNA polymerase II transcription factor binding|p53 binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|integrin binding|protein binding|ATP binding|beta-catenin binding|beta-catenin binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|ubiquitin protein ligase binding|protein kinase A catalytic subunit binding|ionotropic glutamate receptor binding|tau protein binding|tau-protein kinase activity|tau-protein kinase activity|NF-kappaB binding|",10,1.8,7.4,10,0,0,1.8,4,4,0.19,0,0,0.1,3
ENSMUSG00000024122,PDPK1,3-phosphoinositide dependent protein kinase 1,nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|membrane|cytoplasmic membrane-bounded vesicle|cell junction|cell projection|,"type B pancreatic cell development|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|negative regulation of protein kinase activity|hyperosmotic response|signal transduction|epidermal growth factor receptor signaling pathway|positive regulation of phospholipase activity|regulation of endothelial cell migration|negative regulation of cardiac muscle cell apoptotic process|phosphorylation|cell migration|peptidyl-threonine phosphorylation|calcium-mediated signaling|negative regulation of transforming growth factor beta receptor signaling pathway|activation of protein kinase B activity|cellular response to insulin stimulus|negative regulation of toll-like receptor signaling pathway|regulation of I-kappaB kinase/NF-kappaB signaling|regulation of mast cell degranulation|focal adhesion assembly|positive regulation of release of sequestered calcium ion into cytosol|cellular response to epidermal growth factor stimulus|positive regulation of establishment of protein localization to plasma membrane|extrinsic apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|3-phosphoinositide-dependent protein kinase activity|insulin receptor binding|ATP binding|phospholipase activator activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|phospholipase binding|",10,0.7,6.26,10,-0.3,1.11,0.6,4,4,0.19,0,0,-0.3,2
ENSMUSG00000030621,ME3,"malic enzyme 3, NADP(+)-dependent, mitochondrial",mitochondrion|,pyruvate metabolic process|malate metabolic process|oxidation-reduction process|,malic enzyme activity|malate dehydrogenase (decarboxylating) (NAD+) activity|malate dehydrogenase (decarboxylating) (NADP+) activity|oxaloacetate decarboxylase activity|oxidoreductase activity|metal ion binding|NAD binding|,10,0.4,3.03,10,-0.9,5.13,0.8,3.99,3.99,0.191,0,0,-1.7,1.6
ENSMUSG00000032602,SLC25A20,"solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|,molecular_function|,9,0.3,0.629,9,0.8,5.36,0.7,3.97,3.97,0.192,0,0,-0.1,1.9
ENSMUSG00000025330,PADI4,"peptidyl arginine deiminase, type IV",nucleus|cytoplasm|,"immune system process|nucleosome assembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular protein modification process|chromatin modification|protein citrullination|stem cell maintenance|histone H3-R26 citrullination|histone citrullination|histone citrullination|innate immune response|",protein-arginine deiminase activity|protein-arginine deiminase activity|protein-arginine deiminase activity|calcium ion binding|hydrolase activity|arginine deiminase activity|metal ion binding|,10,0.7,3.44,10,-1,6.49,-1,3.97,-3.97,0.192,0,0,-2,0.8
ENSMUSG00000036117,IL5,interleukin 5,extracellular region|extracellular space|,"immune response|positive regulation of cell proliferation|cytokine-mediated signaling pathway|positive regulation of B cell proliferation|positive regulation of eosinophil differentiation|positive regulation of transcription, DNA-templated|positive regulation of JAK-STAT cascade|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of immunoglobulin secretion|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of podosome assembly|",cytokine activity|cytokine activity|interleukin-5 receptor binding|growth factor activity|,10,0.1,0.452,10,0.6,5.2,0.5,3.96,3.96,0.193,0,0,0,1.7
ENSMUSG00000026618,IARS2,"isoleucine-tRNA synthetase 2, mitochondrial",cytoplasm|mitochondrion|mitochondrion|,translation|tRNA aminoacylation for protein translation|isoleucyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA editing activity|catalytic activity|aminoacyl-tRNA ligase activity|isoleucine-tRNA ligase activity|ATP binding|ligase activity|,10,1.2,2.88,10,-0.8,4.56,-0.4,3.95,-3.95,0.193,0,0,-1.3,1.9
ENSMUSG00000000411,TSSK3,testis-specific serine kinase 3,intracellular|intracellular|,protein phosphorylation|multicellular organismal development|spermatogenesis|phosphorylation|cell differentiation|intracellular signal transduction|sperm capacitation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0,0,10,0.6,5.64,0.6,3.94,3.94,0.194,0,0,-0.1,1.8
ENSMUSG00000020777,ACOX1,"acyl-Coenzyme A oxidase 1, palmitoyl",cytoplasm|mitochondrion|peroxisome|peroxisome|peroxisome|peroxisomal membrane|membrane|,very long-chain fatty acid metabolic process|generation of precursor metabolites and energy|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|prostaglandin metabolic process|spermatogenesis|metabolic process|peroxisome fission|fatty acid oxidation|fatty acid oxidation|fatty acid beta-oxidation using acyl-CoA oxidase|lipid homeostasis|oxidation-reduction process|positive regulation of cholesterol homeostasis|,"acyl-CoA dehydrogenase activity|acyl-CoA oxidase activity|acyl-CoA oxidase activity|receptor binding|fatty acid binding|palmitoyl-CoA oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|PDZ domain binding|protein N-terminus binding|flavin adenine dinucleotide binding|FAD binding|",10,0.3,2.86,10,0.2,1.36,0.2,3.94,3.94,0.194,0,0,-0.5,1.2
ENSMUSG00000005615,PCYT1A,"phosphate cytidylyltransferase 1, choline, alpha isoform",cytoplasm|endoplasmic reticulum membrane|membrane|glycogen granule|,lipid metabolic process|phosphatidylcholine biosynthetic process|phosphatidylcholine biosynthetic process|CDP-choline pathway|phospholipid biosynthetic process|biosynthetic process|,catalytic activity|choline-phosphate cytidylyltransferase activity|protein binding|lipid binding|transferase activity|nucleotidyltransferase activity|protein homodimerization activity|,7,-0.5,2.81,7,-0.8,1.84,-0.7,3.92,-3.92,0.195,0,0,-1.9,0.3
ENSMUSG00000023452,PISD,phosphatidylserine decarboxylase,nucleus|mitochondrion|,lipid metabolic process|phospholipid biosynthetic process|,phosphatidylserine decarboxylase activity|lyase activity|carboxy-lyase activity|,8,1.2,6.91,8,0,0,1.2,3.92,3.92,0.195,0,0,0,2
ENSMUSG00000022451,TWF1,"twinfilin, actin-binding protein, homolog 1 (Drosophila)",intracellular|cytoplasm|cytoskeleton|cell-cell junction|actin cytoskeleton|myofibril|filopodium|ruffle membrane|perinuclear region of cytoplasm|,peptidyl-tyrosine phosphorylation|negative regulation of actin filament polymerization|sequestering of actin monomers|regulation of actin phosphorylation|barbed-end actin filament capping|,"actin binding|actin monomer binding|protein tyrosine kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate binding|protein complex binding|",10,0.4,3.12,10,0.3,1.06,0.3,3.91,3.91,0.195,0,0,-0.5,1.6
ENSMUSG00000036500,AKP3,"alkaline phosphatase 3, intestine, not Mn requiring",external side of plasma membrane|,phosphorus metabolic process|dephosphorylation|neural tube development|neurogenesis|multicellular organism growth|post-anal tail morphogenesis|,magnesium ion binding|protease binding|alkaline phosphatase activity|zinc ion binding|hydrolase activity|,10,0.5,2.04,10,0.3,2.43,0.4,3.9,3.9,0.196,0,0,-0.2,1.3
ENSMUSG00000053819,CAMK2D,"calcium/calmodulin-dependent protein kinase II, delta",nucleus|nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|calcium- and calmodulin-dependent protein kinase complex|intercalated disc|membrane|membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|T-tubule|neuromuscular junction|calcium channel complex|calcium channel complex|neuronal cell body|axon initial segment|protein complex|perinuclear region of cytoplasm|,G1/S transition of mitotic cell cycle|response to hypoxia|regulation of sodium ion transport|protein phosphorylation|calcium ion transport|calcium ion transport|regulation of G2/M transition of mitotic cell cycle|positive regulation of cardiac muscle hypertrophy|positive regulation of smooth muscle cell migration|phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|peptidyl-threonine phosphorylation|cellular potassium ion homeostasis|positive regulation of Rac protein signal transduction|protein autophosphorylation|protein autophosphorylation|positive regulation of smooth muscle cell proliferation|relaxation of cardiac muscle|relaxation of cardiac muscle|cardiac muscle contraction|regulation of cellular localization|cell growth involved in cardiac muscle cell development|positive regulation of ERK1 and ERK2 cascade|cardiac muscle cell contraction|cardiac muscle cell contraction|regulation of relaxation of cardiac muscle|regulation of relaxation of cardiac muscle|regulation of sodium ion transmembrane transport|regulation of sodium ion transmembrane transporter activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin-dependent protein kinase activity|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|sodium channel regulator activity|titin binding|ion channel binding|ion channel binding|nitric-oxide synthase binding|",10,-0.4,1.66,10,-0.3,2.53,-0.4,3.9,-3.9,0.196,0,0,-1.3,1.1
ENSMUSG00000005899,SMPD4,sphingomyelin phosphodiesterase 4,endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|trans-Golgi network|trans-Golgi network|membrane|integral component of membrane|,sphingomyelin catabolic process|sphingomyelin catabolic process|glycerophospholipid catabolic process|ceramide biosynthetic process|cellular response to tumor necrosis factor|,sphingomyelin phosphodiesterase activity|hydrolase activity|metal ion binding|sphingomyelin phosphodiesterase D activity|sphingomyelin phosphodiesterase D activity|,10,0,0,10,0.5,5.33,0.4,3.87,3.87,0.198,0,0,-0.3,1.5
ENSMUSG00000033676,GABRB3,"gamma-aminobutyric acid (GABA) A receptor, subunit beta 3",plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|terminal bouton|synapse|postsynaptic membrane|inhibitory synapse|GABA-A receptor complex|GABA-A receptor complex|,"transport|ion transport|chloride transport|signal transduction|gamma-aminobutyric acid signaling pathway|sensory perception of sound|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|neuron development|synaptic transmission, GABAergic|palate development|inner ear receptor cell development|innervation|cellular response to histamine|cochlea development|negative regulation of neuron death|chloride transmembrane transport|chloride transmembrane transport|",GABA-A receptor activity|GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|chloride channel activity|GABA-gated chloride ion channel activity|GABA-gated chloride ion channel activity|AP-2 adaptor complex binding|,10,0.3,0.00443,10,-1,6.84,-1,3.85,-3.85,0.199,0,0,-2,0.1
ENSMUSG00000004221,IKBKG,inhibitor of kappaB kinase gamma,intracellular|nucleus|cytoplasm|cytoplasm|cytosol|IkappaB kinase complex|,"B cell homeostasis|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|activation of NF-kappaB-inducing kinase activity|phosphorylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of NF-kappaB transcription factor activity|",protein binding|kinase activity|transferase activity|protein domain specific binding|protein homodimerization activity|peroxisome proliferator activated receptor binding|metal ion binding|protein heterodimerization activity|,6,-1.5,6.15,7,0.6,2.92,-1.4,3.82,-3.82,0.201,0,0,-3,1
ENSMUSG00000026664,PHYH,phytanoyl-CoA hydroxylase,mitochondrion|peroxisome|peroxisome|,fatty acid alpha-oxidation|fatty acid alpha-oxidation|isoprenoid metabolic process|oxidation-reduction process|methyl-branched fatty acid metabolic process|,catalytic activity|protein binding|oxidoreductase activity|L-ascorbic acid binding|metal ion binding|cofactor binding|phytanoyl-CoA dioxygenase activity|dioxygenase activity|,9,0.7,4.18,9,0.3,0.552,0.6,3.72,3.72,0.208,0,0,-0.3,1.7
ENSMUSG00000026615,EPRS,glutamyl-prolyl-tRNA synthetase,cytoplasm|membrane|ribonucleoprotein complex|GAIT complex|GAIT complex|,translation|regulation of translation|tRNA aminoacylation for protein translation|glutamyl-tRNA aminoacylation|prolyl-tRNA aminoacylation|metabolic process|negative regulation of translation|negative regulation of translation|tRNA aminoacylation|cellular response to interferon-gamma|cellular response to interferon-gamma|,"nucleotide binding|RNA binding|catalytic activity|aminoacyl-tRNA ligase activity|glutamate-tRNA ligase activity|proline-tRNA ligase activity|ATP binding|ligase activity|ligase activity, forming aminoacyl-tRNA and related compounds|RNA stem-loop binding|",8,0.1,0.187,8,0.6,5.03,0.5,3.68,3.68,0.21,0,0,-0.9,1.9
ENSMUSG00000025745,HADHA,"hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial fatty acid beta-oxidation multienzyme complex|mitochondrial nucleoid|,lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|fatty acid beta-oxidation|metabolic process|response to insulin|response to drug|oxidation-reduction process|,"fatty-acyl-CoA binding|catalytic activity|3-hydroxyacyl-CoA dehydrogenase activity|acetyl-CoA C-acyltransferase activity|enoyl-CoA hydratase activity|enoyl-CoA hydratase activity|oxidoreductase activity|long-chain-enoyl-CoA hydratase activity|long-chain-3-hydroxyacyl-CoA dehydrogenase activity|long-chain-3-hydroxyacyl-CoA dehydrogenase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|lyase activity|protein complex binding|coenzyme binding|NAD binding|",10,0.6,1.92,10,0.2,2.22,0.2,3.67,3.67,0.211,0,0,-0.4,1.4
ENSMUSG00000033373,FNTB,"farnesyltransferase, CAAX box, beta",microtubule associated complex|protein farnesyltransferase complex|protein complex|,positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|response to inorganic substance|response to organic cyclic compound|protein farnesylation|response to cytokine|wound healing|regulation of cell proliferation|positive regulation of cell cycle|positive regulation of fibroblast proliferation|positive regulation of nitric-oxide synthase biosynthetic process|,catalytic activity|farnesyltranstransferase activity|prenyltransferase activity|protein farnesyltransferase activity|protein farnesyltransferase activity|drug binding|zinc ion binding|zinc ion binding|transferase activity|isoprenoid binding|peptide binding|metal ion binding|,7,-1.2,0.515,6,-0.9,3.55,-1,3.59,-3.59,0.216,0,0,-2,0.4
ENSMUSG00000003053,CYP2C29,"cytochrome P450, family 2, subfamily c, polypeptide 29",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|caffeine oxidase activity|metal ion binding|aromatase activity|",10,1,4.15,10,0.3,1.67,0.6,3.56,3.56,0.218,0,0,-0.5,1.9
ENSMUSG00000006589,APRT,adenine phosphoribosyl transferase,nucleus|cytoplasm|extracellular vesicular exosome|,purine ribonucleoside salvage|purine ribonucleoside salvage|adenine salvage|lactation|grooming behavior|nucleoside metabolic process|adenine metabolic process|adenine metabolic process|adenine metabolic process|,"adenine binding|adenine phosphoribosyltransferase activity|adenine phosphoribosyltransferase activity|adenine phosphoribosyltransferase activity|AMP binding|transferase activity|transferase activity, transferring glycosyl groups|",10,0.5,1.39,10,-0.5,5.52,-0.4,3.55,-3.55,0.219,0,0,-1.5,0.8
ENSMUSG00000074179,GM10639,predicted gene 10639,cellular_component|,biological_process|,molecular_function|,9,1.2,6.47,9,0.1,0.104,1.2,3.55,3.55,0.219,0,0,-0.1,2
ENSMUSG00000025991,CPS1,carbamoyl-phosphate synthetase 1,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial nucleoid|protein complex|,urea cycle|urea cycle|glycogen catabolic process|proteolysis|glutamine catabolic process|nitrogen compound metabolic process|metabolic process|triglyceride catabolic process|response to lipopolysaccharide|positive regulation of vasodilation|nitric oxide metabolic process|homocysteine metabolic process|anion homeostasis|carbamoyl phosphate biosynthetic process|,nucleotide binding|catalytic activity|carbamoyl-phosphate synthase (ammonia) activity|carbamoyl-phosphate synthase (ammonia) activity|endopeptidase activity|calcium ion binding|protein binding|ATP binding|phospholipid binding|glutamate binding|ligase activity|protein complex binding|metal ion binding|modified amino acid binding|,10,1.2,2.42,10,0.3,3.6,0.3,3.53,3.53,0.22,0,0,-0.2,1.9
ENSMUSG00000059146,NTRK3,"neurotrophic tyrosine kinase, receptor, type 3",cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,activation of MAPK activity|neuron migration|negative regulation of protein phosphorylation|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|positive regulation of cell proliferation|positive regulation of gene expression|phosphorylation|cell differentiation|positive regulation of cell migration|activation of protein kinase B activity|activation of Ras GTPase activity|positive regulation of peptidyl-serine phosphorylation|neurotrophin signaling pathway|mechanoreceptor differentiation|protein autophosphorylation|neuron fate specification|positive regulation of axon extension involved in regeneration|negative regulation of astrocyte differentiation|positive regulation of positive chemotaxis|negative regulation of cell death|lens fiber cell differentiation|positive regulation of actin cytoskeleton reorganization|,"nucleotide binding|p53 binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|neurotrophin receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|ephrin receptor binding|",10,-0.4,2.12,10,0.4,2.74,0.4,3.52,3.52,0.221,0,0,-1,1.3
ENSMUSG00000026893,GCA,grancalcin,cytoplasm|cytoplasm|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,0.2,1.8,10,0.8,2.84,0.6,3.51,3.51,0.221,0,0,-0.4,1.8
ENSMUSG00000052783,GRK4,G protein-coupled receptor kinase 4,cytoplasm|cytosol|dendrite|neuronal cell body|,desensitization of G-protein coupled receptor protein signaling pathway|G-protein coupled receptor internalization|protein phosphorylation|signal transduction|phosphorylation|receptor internalization|termination of G-protein coupled receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|G-protein coupled receptor kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|rhodopsin kinase activity|",10,1.6,6.9,10,-0.7,1.09,1.6,3.5,3.5,0.222,0,0,-0.6,3
ENSMUSG00000039913,PAK7,p21 protein (Cdc42/Rac)-activated kinase 7,intracellular|nucleus|cytoplasm|mitochondrion|,protein phosphorylation|apoptotic process|cytoskeleton organization|learning|memory|locomotory behavior|cell growth|phosphorylation|signal transduction by phosphorylation|negative regulation of extrinsic apoptotic signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.0471,10,0.8,6.26,0.8,3.49,3.49,0.223,0,0,-0.5,2
ENSMUSG00000013539,TANGO2,transport and golgi organization 2,mitochondrion|,biological_process|,molecular_function|,10,0.1,0.447,10,0.5,4.35,0.4,3.45,3.45,0.225,0,0,-0.6,1.5
ENSMUSG00000096472,CDKN2D,"cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)",nucleus|cytoplasm|,regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|DNA synthesis involved in DNA repair|cell cycle|cell cycle arrest|sensory perception of sound|negative regulation of cell proliferation|response to UV|negative regulation of cell growth|response to retinoic acid|response to vitamin D|negative regulation of phosphorylation|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|autophagic cell death|negative regulation of protein serine/threonine kinase activity|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|,cyclin-dependent protein serine/threonine kinase inhibitor activity|protein kinase binding|,10,0.2,0.854,10,0.4,3.11,0.3,3.4,3.4,0.229,0,0,-0.2,1.4
ENSMUSG00000074797,ITPA,inosine triphosphatase (nucleoside triphosphate pyrophosphatase),cytoplasm|,ITP catabolic process|nucleotide metabolic process|nucleoside triphosphate catabolic process|chromosome organization|,nucleotide binding|hydrolase activity|dITP diphosphatase activity|dITP diphosphatase activity|ITP diphosphatase activity|XTP diphosphatase activity|metal ion binding|nucleoside-triphosphate diphosphatase activity|,10,0.1,0.132,10,-0.5,3.76,-0.5,3.38,-3.38,0.23,0,0,-1.6,0.4
ENSMUSG00000022962,GART,phosphoribosylglycinamide formyltransferase,cytoplasm|extracellular vesicular exosome|,purine nucleotide biosynthetic process|'de novo' IMP biosynthetic process|glycine metabolic process|metabolic process|biosynthetic process|purine nucleobase biosynthetic process|ribonucleoside monophosphate biosynthetic process|response to organic substance|response to inorganic substance|tetrahydrofolate biosynthetic process|,"nucleotide binding|catalytic activity|phosphoribosylamine-glycine ligase activity|phosphoribosylformylglycinamidine cyclo-ligase activity|phosphoribosylglycinamide formyltransferase activity|ATP binding|methyltransferase activity|transferase activity|hydroxymethyl-, formyl- and related transferase activity|ligase activity|metal ion binding|",4,-1,4.65,3,0.6,2.17,-1,3.36,-3.36,0.232,0,0,-2,1.2
ENSMUSG00000033323,CTDP1,"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1",spindle pole|nucleus|cytoplasm|centrosome|spindle|cytoskeleton|actin cytoskeleton|midbody|spindle midzone|,protein dephosphorylation|cell cycle|mitotic nuclear division|exit from mitosis|cell division|,phosphoprotein phosphatase activity|protein binding|CTD phosphatase activity|hydrolase activity|,6,0.2,0.883,5,-0.5,3.48,-0.5,3.34,-3.34,0.233,0,0,-2,0.6
ENSMUSG00000026675,HSD17B7,hydroxysteroid (17-beta) dehydrogenase 7,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|metabolic process|oxidation-reduction process|,3-keto sterol reductase activity|estradiol 17-beta-dehydrogenase activity|prolactin receptor binding|oxidoreductase activity|,10,0.2,0.911,10,0.3,2.69,0.2,3.32,3.32,0.235,0,0,-0.6,1.3
ENSMUSG00000026874,HC,hemolytic complement,extracellular region|membrane attack complex|extracellular space|extracellular vesicular exosome|,"in utero embryonic development|immune system process|inflammatory response|complement activation, alternative pathway|complement activation, classical pathway|positive regulation vascular endothelial growth factor production|negative regulation of macrophage chemotaxis|cytolysis|innate immune response|positive regulation of angiogenesis|positive regulation of chemokine secretion|",endopeptidase inhibitor activity|,10,-0.3,2.27,10,0.5,2.92,-0.4,3.31,-3.31,0.235,0,0,-1.3,1.3
ENSMUSG00000079317,TRAPPC2,trafficking protein particle complex 2,TRAPP complex|perinuclear region of cytoplasm|,"skeletal system development|regulation of transcription, DNA-templated|",protein binding|transcription factor binding|ion channel binding|,10,-0.6,0.973,10,0.5,3.93,0.4,3.27,3.27,0.238,0,0,-1.2,1.6
ENSMUSG00000039197,ADK,adenosine kinase,nucleus|nucleus|cytoplasm|cytosol|,purine ribonucleoside salvage|AMP biosynthetic process|dATP biosynthetic process|positive regulation of cardiac muscle hypertrophy|phosphorylation|positive regulation of T cell proliferation|type B pancreatic cell proliferation|adenosine metabolic process|,"nucleotide binding|adenosine kinase activity|adenosine kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|poly(A) RNA binding|metal ion binding|",10,-0.7,3.89,10,0,0,-0.6,3.26,-3.26,0.239,0,0,-1.8,0.1
ENSMUSG00000030002,DUSP11,dual specificity phosphatase 11 (RNA/RNP complex 1-interacting),cellular_component|nucleus|,protein dephosphorylation|RNA metabolic process|dephosphorylation|polynucleotide 5' dephosphorylation|,"RNA binding|polynucleotide 5'-phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|poly(A) RNA binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|nucleotide phosphatase activity, acting on free nucleotides|IDP phosphatase activity|",10,-0.5,3.87,10,0.6,5.01,0.4,3.26,3.26,0.239,0,0,-1.1,1.6
ENSMUSG00000062248,CKS2,CDC28 protein kinase regulatory subunit 2,None,cell cycle|meiosis I|phosphorylation|cell division|,kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|,9,0.7,5.02,10,0.1,0.141,0.6,3.2,3.2,0.244,0,0,-0.3,1.8
ENSMUSG00000022991,LALBA,"lactalbumin, alpha",extracellular region|,lactose biosynthetic process|,lactose synthase activity|calcium ion binding|protein binding|metal ion binding|,10,-0.9,4.93,10,-0.2,0.906,-0.8,3.19,-3.19,0.244,0,0,-1.9,0.1
ENSMUSG00000061286,EXOSC5,exosome component 5,exosome (RNase complex)|nucleus|cytoplasm|transcriptionally active chromatin|,rRNA processing|RNA catabolic process|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|DNA deamination|defense response to virus|,molecular_function|RNA binding|,9,-0.6,3.65,9,0,0,-0.6,3.19,-3.19,0.244,0,0,-1.8,0.8
ENSMUSG00000039253,FN3KRP,fructosamine 3 kinase related protein,cellular_component|,biological_process|phosphorylation|,"molecular_function|phosphofructokinase activity|phosphorylase kinase regulator activity|cobinamide kinase activity|phytol kinase activity|kinase activity|phosphatidylinositol phosphate kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phenol kinase activity|cyclin-dependent protein kinase activating kinase regulator activity|inositol tetrakisphosphate 2-kinase activity|heptose 7-phosphate kinase activity|aminoglycoside phosphotransferase activity|phosphatidylinositol 3-kinase activity|eukaryotic elongation factor-2 kinase regulator activity|eukaryotic elongation factor-2 kinase activator activity|LPPG:FO 2-phospho-L-lactate transferase activity|cytidine kinase activity|glycerate 2-kinase activity|(S)-lactate 2-kinase activity|phosphoserine:homoserine phosphotransferase activity|L-seryl-tRNA(Sec) kinase activity|phosphocholine transferase activity|polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide kinase activity|GTP-dependent polynucleotide kinase activity|farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|geraniol kinase activity|geranylgeraniol kinase activity|CTP:geranylgeraniol kinase activity|prenol kinase activity|1-phosphatidylinositol-5-kinase activity|1-phosphatidylinositol-3-phosphate 4-kinase activity|phosphatidylinositol-3,4-bisphosphate 5-kinase activity|phosphatidylinositol bisphosphate kinase activity|inositol-3,4,6-trisphosphate 1-kinase activity|inositol 5-diphosphate pentakisphosphate 5-kinase activity|inositol diphosphate tetrakisphosphate kinase activity|",10,0.5,1.66,10,0.3,2.01,0.3,3.17,3.17,0.246,0,0,-1,1.4
ENSMUSG00000024014,PIM1,proviral integration site 1,cytoplasm|,protein phosphorylation|cell proliferation|phosphorylation|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|negative regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|protein autophosphorylation|,nucleotide binding|protein serine/threonine kinase activity|ATP binding|transcription factor binding|kinase activity|transferase activity|manganese ion binding|ribosomal small subunit binding|,10,0,0,10,0.4,4.82,0.3,3.13,3.13,0.249,0,0,-0.4,1.4
ENSMUSG00000032017,GRIK4,"glutamate receptor, ionotropic, kainate 4",nucleus|plasma membrane|membrane|integral component of membrane|cell junction|axon|dendrite|dendrite|kainate selective glutamate receptor complex|presynaptic membrane|terminal bouton|perikaryon|synapse|postsynaptic membrane|,"transport|ion transport|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|",receptor activity|ionotropic glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|kainate selective glutamate receptor activity|,10,-0.4,1.67,10,0.6,5.22,0.5,3.12,3.12,0.25,0,0,-0.7,1.8
ENSMUSG00000041297,CDK13,cyclin-dependent kinase 13,cyclin K-CDK13 complex|extracellular space|nucleus|nuclear speck|nuclear cyclin-dependent protein kinase holoenzyme complex|,"alternative mRNA splicing, via spliceosome|mRNA processing|protein phosphorylation|RNA splicing|phosphorylation|hemopoiesis|phosphorylation of RNA polymerase II C-terminal domain|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|cyclin binding|poly(A) RNA binding|",9,0.4,3.75,9,-0.6,3.55,0.3,3.09,3.09,0.252,0,0,-1.6,1.1
ENSMUSG00000028479,GNE,glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase,cytoplasm|cytosol|,carbohydrate metabolic process|UDP-N-acetylglucosamine metabolic process|N-acetylneuraminate metabolic process|metabolic process|phosphorylation|carbohydrate phosphorylation|,"nucleotide binding|catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|ATP binding|UDP-N-acetylglucosamine 2-epimerase activity|N-acylmannosamine kinase activity|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|hydrolase activity|isomerase activity|metal ion binding|",9,0.5,1.5,10,0.7,2.09,0.6,3.07,3.07,0.254,0,0,-0.3,1.8
ENSMUSG00000026456,CYB5R1,cytochrome b5 reductase 1,mitochondrion|mitochondrion|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,lipid metabolic process|steroid biosynthetic process|steroid metabolic process|sterol biosynthetic process|oxidation-reduction process|,"cytochrome-b5 reductase activity, acting on NAD(P)H|oxidoreductase activity|",10,0.2,1.54,10,0.4,2.08,0.3,3.07,3.07,0.254,0,0,-0.5,1.5
ENSMUSG00000026209,DNPEP,aspartyl aminopeptidase,nucleus|cytoplasm|blood microparticle|,proteolysis|,aminopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,1.3,2.68,10,-0.3,2.81,-0.3,3.05,-3.05,0.255,0,0,-1.2,1.9
ENSMUSG00000022323,HRSP12,heat-responsive protein 12,mitochondrion|extracellular vesicular exosome|,None,nuclease activity|endonuclease activity|hydrolase activity|deaminase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|poly(A) RNA binding|retroviral 3' processing activity|,10,-0.4,2.59,10,-0.5,0.643,-0.4,3.03,-3.03,0.257,0,0,-1.6,0.7
ENSMUSG00000009630,PPP2CB,"protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform","protein phosphatase type 2A complex|chromosome, centromeric region|nucleus|chromosome|cytoplasm|cytoskeleton|extracellular vesicular exosome|",protein dephosphorylation|apoptotic mitochondrial changes|regulation of gene expression|response to endoplasmic reticulum stress|response to hydrogen peroxide|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of Ras protein signal transduction|response to antibiotic|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein binding|protein C-terminus binding|hydrolase activity|metal ion binding|,10,-0.8,2.5,10,0.6,2.03,-0.7,3.03,-3.03,0.257,0,0,-1.8,1.3
ENSMUSG00000029635,CDK8,cyclin-dependent kinase 8,nucleus|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|phosphorylation|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.6,4.08,0.6,2.99,2.99,0.26,0,0,-0.1,1.8
ENSMUSG00000021796,BMPR1A,"bone morphogenetic protein receptor, type 1A",plasma membrane|caveola|membrane|integral component of membrane|dendrite|neuronal cell body|,"in utero embryonic development|mesoderm formation|somitogenesis|Mullerian duct regression|positive regulation of mesenchymal cell proliferation|heart morphogenesis|endocardial cushion formation|transcription from RNA polymerase II promoter|protein phosphorylation|immune response|transmembrane receptor protein serine/threonine kinase signaling pathway|pattern specification process|ectoderm development|nervous system development|endoderm development|heart development|dorsal/ventral axis specification|anterior/posterior pattern specification|dorsal/ventral pattern formation|positive regulation of pathway-restricted SMAD protein phosphorylation|neural crest cell development|phosphorylation|stem cell maintenance|pituitary gland development|neural plate mediolateral regionalization|cell differentiation|lung development|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|hindlimb morphogenesis|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|positive regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|paraxial mesoderm development|paraxial mesoderm development|paraxial mesoderm structural organization|lateral mesoderm development|regulation of lateral mesodermal cell fate specification|mesendoderm development|embryonic organ development|developmental growth|embryonic morphogenesis|positive regulation of epithelial cell proliferation|negative regulation of neurogenesis|cartilage development|palate development|positive regulation of SMAD protein import into nucleus|neural plate pattern specification|heart formation|regulation of cellular senescence|","nucleotide binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|SMAD binding|metal ion binding|",10,0,0,10,-0.5,4.48,-0.4,2.99,-2.99,0.26,0,0,-1.6,0.4
ENSMUSG00000022752,TOMM70A,translocase of outer mitochondrial membrane 70 homolog A (yeast),mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|membrane|integral component of membrane|,None,protein binding|,8,-0.5,3.9,7,0.4,1.86,-0.5,2.99,-2.99,0.26,0,0,-1.7,1.1
ENSMUSG00000003810,MAST2,microtubule associated serine/threonine kinase 2,cytoplasm|cytoskeleton|microtubule cytoskeleton|membrane|cell junction|,protein phosphorylation|phosphorylation|regulation of interleukin-12 biosynthetic process|spermatid differentiation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|microtubule binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphatase binding|metal ion binding|",10,0.3,2.91,10,-0.5,4.51,-0.4,2.97,-2.97,0.262,0,0,-1.5,0.8
ENSMUSG00000002010,IDH3G,"isocitrate dehydrogenase 3 (NAD+), gamma",nucleus|mitochondrion|mitochondrion|,tricarboxylic acid cycle|isocitrate metabolic process|2-oxoglutarate metabolic process|NADH metabolic process|negative regulation of growth|oxidation-reduction process|,"nucleotide binding|magnesium ion binding|isocitrate dehydrogenase (NAD+) activity|ATP binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|metal ion binding|NAD binding|",10,-0.4,2.8,10,-0.2,0.608,-0.3,2.96,-2.96,0.263,0,0,-1.5,1
ENSMUSG00000025468,CALY,calcyon neuron-specific vesicular protein,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,endocytosis|dopamine receptor signaling pathway|positive regulation of endocytosis|clathrin coat assembly|,clathrin light chain binding|protein complex binding|,10,-0.2,0.366,10,-0.4,2.98,-0.3,2.93,-2.93,0.265,0,0,-1.5,0.3
ENSMUSG00000000263,GLRA1,"glycine receptor, alpha 1 subunit",intracellular|cell|plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|intracellular membrane-bounded organelle|synapse|postsynaptic membrane|inhibitory synapse|,"action potential|startle response|startle response|regulation of respiratory gaseous exchange by neurological system process|transport|ion transport|anion transport|chloride transport|muscle contraction|neuropeptide signaling pathway|synaptic transmission|acrosome reaction|visual perception|adult walking behavior|ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|regulation of membrane potential|regulation of respiratory gaseous exchange|neuromuscular process controlling posture|neuromuscular process|protein homooligomerization|protein heterooligomerization|negative regulation of transmission of nerve impulse|synaptic transmission, glycinergic|synaptic transmission, glycinergic|righting reflex|regulation of inhibitory postsynaptic membrane potential|chloride transmembrane transport|chloride transmembrane transport|positive regulation of acrosome reaction|",extracellular ligand-gated ion channel activity|chloride channel activity|glycine binding|glycine binding|glycine binding|extracellular-glycine-gated ion channel activity|extracellular-glycine-gated chloride channel activity|extracellular-glycine-gated chloride channel activity|extracellular-glycine-gated chloride channel activity|extracellular-glycine-gated chloride channel activity|transmitter-gated ion channel activity|taurine binding|,10,0.6,3.74,10,0.2,0.534,0.5,2.93,2.93,0.265,0,0,-0.2,1.8
ENSMUSG00000028161,PPP3CA,"protein phosphatase 3, catalytic subunit, alpha isoform",intracellular|nucleus|nucleus|cytoplasm|mitochondrion|cytosol|cytosol|plasma membrane|calcineurin complex|calcineurin complex|membrane|Z disc|,G1/S transition of mitotic cell cycle|protein dephosphorylation|protein dephosphorylation|protein import into nucleus|calcium ion transport|transition between fast and slow fiber|dephosphorylation|calcium-mediated signaling|calcineurin-NFAT signaling cascade|multicellular organismal response to stress|cellular response to drug|positive regulation of transcription from RNA polymerase II promoter|negative regulation of insulin secretion|skeletal muscle fiber development|regulation of synaptic transmission|response to calcium ion|regulation of excitatory postsynaptic membrane potential|cellular response to glucose stimulus|,phosphoprotein phosphatase activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|calcium-dependent protein serine/threonine phosphatase activity|protein binding|calmodulin binding|drug binding|hydrolase activity|enzyme binding|calmodulin-dependent protein phosphatase activity|metal ion binding|protein heterodimerization activity|protein dimerization activity|,10,0,0,10,0.6,5.56,0.5,2.93,2.93,0.265,0,0,-0.7,1.8
ENSMUSG00000026117,ZAP70,zeta-chain (TCR) associated protein kinase,immunological synapse|intracellular|cytoplasm|cytosol|plasma membrane|plasma membrane|cell-cell junction|membrane|T cell receptor complex|membrane raft|,immune system process|protein phosphorylation|protein phosphorylation|immune response|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|intracellular signal transduction|beta selection|positive thymic T cell selection|positive thymic T cell selection|negative thymic T cell selection|thymic T cell selection|positive regulation of T cell differentiation|positive regulation of T cell differentiation|positive regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell proliferation|protein autophosphorylation|protein autophosphorylation|positive regulation of calcium-mediated signaling|T cell receptor signaling pathway|,"nucleotide binding|phosphotyrosine binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.5,3.77,10,0.5,1.65,1.4,2.91,2.91,0.267,0,0,0,2.7
ENSMUSG00000021822,PLAU,"plasminogen activator, urokinase",extracellular region|extracellular space|cell surface|membrane|extracellular vesicular exosome|,angiogenesis|response to hypoxia|proteolysis|positive regulation of cell proliferation|regulation of receptor activity|smooth muscle cell migration|regulation of smooth muscle cell migration|positive regulation of smooth muscle cell migration|phosphorylation|regulation of cell adhesion mediated by integrin|wound healing|regulation of cell proliferation|fibrinolysis|skeletal muscle tissue regeneration|positive regulation of ovulation|neuron death|regulation of smooth muscle cell-matrix adhesion|regulation of hepatocyte proliferation|positive regulation of reactive oxygen species metabolic process|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|kinase activity|transferase activity|hydrolase activity|,10,1.5,6.33,10,-0.9,4.51,1.5,2.9,2.9,0.268,0,0,-1.5,2.8
ENSMUSG00000020804,AANAT,arylalkylamine N-acetyltransferase,cytoplasm|perinuclear region of cytoplasm|,N-terminal protein amino acid acetylation|circadian rhythm|response to zinc ion|response to organic cyclic compound|melatonin biosynthetic process|response to insulin|response to prostaglandin E|response to copper ion|rhythmic process|cellular response to cAMP|,"aralkylamine N-acetyltransferase activity|arylamine N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|14-3-3 protein binding|",10,0.7,4.97,10,0.1,0.0625,0.6,2.89,2.89,0.269,0,0,-0.1,1.8
ENSMUSG00000020660,POMC,pro-opiomelanocortin-alpha,extracellular region|extracellular space|cytoplasm|peroxisomal matrix|secretory granule|,generation of precursor metabolites and energy|signal transduction|neuropeptide signaling pathway|cell-cell signaling|regulation of blood pressure|regulation of appetite|negative regulation of tumor necrosis factor production|cellular pigmentation|glucose homeostasis|positive regulation of transcription from RNA polymerase II promoter|regulation of glycogen metabolic process|regulation of corticosterone secretion|,G-protein coupled receptor binding|receptor binding|hormone activity|hormone activity|type 3 melanocortin receptor binding|type 4 melanocortin receptor binding|type 1 melanocortin receptor binding|,10,0.3,3.04,10,0.1,0.428,0.3,2.89,2.89,0.269,0,0,-0.8,1.5
ENSMUSG00000039109,F13A1,"coagulation factor XIII, A1 subunit",extracellular region|cytoplasm|blood microparticle|,blood coagulation|blood coagulation|hemostasis|peptide cross-linking|,"protein-glutamine gamma-glutamyltransferase activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,-0.2,1.02,10,0.6,4.8,0.5,2.88,2.88,0.27,0,0,-0.5,1.8
ENSMUSG00000041135,RIPK2,receptor (TNFRSF)-interacting serine-threonine kinase 2,intracellular|cytoplasm|cytoplasm|cytoskeleton|vesicle|protein complex|,positive regulation of cytokine-mediated signaling pathway|adaptive immune response|immune system process|positive regulation of T-helper 1 type immune response|protein phosphorylation|apoptotic process|I-kappaB kinase/NF-kappaB signaling|positive regulation of peptidyl-threonine phosphorylation|phosphorylation|positive regulation of protein ubiquitination|lipopolysaccharide-mediated signaling pathway|positive regulation of chemokine production|positive regulation of interferon-gamma production|positive regulation of interleukin-2 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of stress-activated MAPK cascade|positive regulation of immature T cell proliferation|positive regulation of peptidyl-serine phosphorylation|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway|T cell proliferation|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to exogenous dsRNA|innate immune response|innate immune response|positive regulation of T-helper 1 cell differentiation|positive regulation of JNK cascade|positive regulation of alpha-beta T cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|defense response to Gram-positive bacterium|T cell receptor signaling pathway|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|nucleotide-binding oligomerization domain containing 1 signaling pathway|nucleotide-binding oligomerization domain containing 2 signaling pathway|nucleotide-binding oligomerization domain containing 2 signaling pathway|response to interleukin-1|response to interleukin-12|response to interleukin-18|cellular response to lipopolysaccharide|cellular response to lipoteichoic acid|cellular response to peptidoglycan|cellular response to muramyl dipeptide|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|LIM domain binding|protein homodimerization activity|CARD domain binding|",10,1,1.74,10,0.9,1.35,1,2.87,2.87,0.27,0,0,-0.3,2
ENSMUSG00000038975,RABGGTB,"Rab geranylgeranyl transferase, b subunit",Rab-protein geranylgeranyltransferase complex|,protein geranylgeranylation|,catalytic activity|prenyltransferase activity|Rab geranylgeranyltransferase activity|zinc ion binding|transferase activity|Rab GTPase binding|metal ion binding|,2,0.4,0.655,4,-0.5,3.69,-0.4,2.87,-2.87,0.27,0,0,-2,1.2
ENSMUSG00000058579,CELA2A,"chymotrypsin-like elastase family, member 2A",extracellular region|keratohyalin granule|,proteolysis|establishment of skin barrier|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|serine hydrolase activity|serine hydrolase activity|serine hydrolase activity|,10,0.4,2.38,10,0.4,0.666,0.4,2.86,2.86,0.271,0,0,-0.7,1.5
ENSMUSG00000022680,PDXDC1,pyridoxal-dependent decarboxylase domain containing 1,Golgi apparatus|intracellular membrane-bounded organelle|,biological_process|carboxylic acid metabolic process|,"catalytic activity|phosphoenolpyruvate carboxykinase activity|gamma-glutamyl carboxylase activity|3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity|lyase activity|carboxy-lyase activity|2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity|bis(4-chlorophenyl)acetate decarboxylase activity|3,5-dibromo-4-hydroxybenzoate decarboxylase activity|2-hydroxyisobutyrate decarboxylase activity|2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity|pyridoxal phosphate binding|2-hydroxyisophthalate decarboxylase activity|dimethylmalonate decarboxylase activity|2,4,4-trimethyl-3-oxopentanoate decarboxylase activity|4,4-dimethyl-3-oxopentanoate decarboxylase activity|2,3,6-trihydroxyisonicotinate decarboxylase activity|phenanthrene-4,5-dicarboxylate decarboxylase activity|pyrrole-2-carboxylate decarboxylase activity|terephthalate decarboxylase activity|malonate semialdehyde decarboxylase activity|5-amino-4-imidazole carboxylate lyase activity|2-keto-4-methylthiobutyrate aminotransferase activity|2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity|",10,0.5,5.41,10,0,0,0.5,2.75,2.75,0.281,0,0,-0.3,1.8
ENSMUSG00000048895,CDK5R1,"cyclin-dependent kinase 5, regulatory subunit 1 (p35)",nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|postsynaptic density|membrane|cyclin-dependent protein kinase 5 holoenzyme complex|axon|dendrite|growth cone|neuromuscular junction|neuronal cell body|dendritic spine|contractile fiber|perinuclear region of cytoplasm|,"neuron migration|neuron migration|protein phosphorylation|neuron cell-cell adhesion|G-protein coupled acetylcholine receptor signaling pathway|axon guidance|axonal fasciculation|brain development|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|cerebellum development|cerebellum development|superior olivary nucleus maturation|hippocampus development|cerebral cortex radially oriented cell migration|layer formation in cerebral cortex|neuron differentiation|negative regulation of axon extension|neuron projection development|regulation of actin cytoskeleton organization|serine phosphorylation of STAT3 protein|ionotropic glutamate receptor signaling pathway|positive regulation of neuron apoptotic process|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|ephrin receptor signaling pathway|rhythmic process|regulation of cell cycle|regulation of dendritic spine morphogenesis|regulation of microtubule cytoskeleton organization|positive regulation of cell cycle arrest|positive regulation of protein serine/threonine kinase activity|positive regulation of protein serine/threonine kinase activity|positive regulation of protein targeting to membrane|",cyclin-dependent protein serine/threonine kinase activity|calcium ion binding|protein binding|cytoskeletal protein binding|kinase activity|cyclin-dependent protein kinase 5 activator activity|cyclin-dependent protein kinase 5 activator activity|cyclin-dependent protein kinase 5 activator activity|transferase activity|protein kinase binding|protein serine/threonine kinase activator activity|cadherin binding|ephrin receptor binding|,10,0.6,3.33,10,0.2,0.747,0.3,2.73,2.73,0.283,0,0,-0.4,1.6
ENSMUSG00000015112,SLC25A13,"solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|membrane|integral component of membrane|,ATP biosynthetic process|transport|aspartate transport|aspartate transport|L-glutamate transport|L-glutamate transport|malate-aspartate shuttle|malate-aspartate shuttle|cellular respiration|response to calcium ion|transmembrane transport|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|L-glutamate transmembrane transporter activity|calcium ion binding|L-aspartate transmembrane transporter activity|metal ion binding|,10,0.2,0.455,10,0.3,2.43,0.3,2.71,2.71,0.285,0,0,-0.6,1.5
ENSMUSG00000028179,CTH,cystathionase (cystathionine gamma-lyase),nucleus|cytoplasm|extracellular vesicular exosome|,glutathione metabolic process|negative regulation of cell proliferation|cellular amino acid biosynthetic process|protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine|cysteine biosynthetic process|negative regulation of cell growth|negative regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|protein sulfhydration|protein sulfhydration|protein sulfhydration|homocysteine metabolic process|positive regulation of NF-kappaB transcription factor activity|protein homotetramerization|hydrogen sulfide biosynthetic process|negative regulation of apoptotic signaling pathway|,catalytic activity|cystathionine beta-lyase activity|cystathionine gamma-lyase activity|cystathionine gamma-lyase activity|protein binding|calmodulin binding|lyase activity|pyridoxal phosphate binding|L-cystine L-cysteine-lyase (deaminating)|L-cystine L-cysteine-lyase (deaminating)|L-cystine L-cysteine-lyase (deaminating)|L-cysteine desulfhydrase activity|,10,1,4.92,10,0.2,0.595,0.9,2.69,2.69,0.287,0,0,-0.3,2
ENSMUSG00000083282,CTSF,cathepsin F,lysosome|extracellular vesicular exosome|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,-0.2,0.632,10,-0.3,2.24,-0.3,2.65,-2.65,0.291,0,0,-1.4,0.9
ENSMUSG00000053004,HRH1,histamine receptor H1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|synaptic transmission|memory|visual learning|negative regulation of steroid biosynthetic process|regulation of vascular permeability|positive regulation of nitric oxide biosynthetic process|positive regulation of vasoconstriction|regulation of synaptic plasticity|eosinophil chemotaxis|rhythmic process|calcium ion import|cellular response to histamine|manganese ion transmembrane transport|,signal transducer activity|G-protein coupled receptor activity|histamine receptor activity|calcium ion transmembrane transporter activity|histamine binding|,10,-0.2,0.501,10,-0.8,3.96,-0.5,2.63,-2.63,0.293,0,0,-1.9,0.9
ENSMUSG00000033624,PDPR,pyruvate dehydrogenase phosphatase regulatory subunit,cytoplasm|mitochondrion|,glycine catabolic process|oxidation-reduction process|,molecular_function|aminomethyltransferase activity|oxidoreductase activity|,10,0.8,5.24,10,0,0,0.7,2.61,2.61,0.295,0,0,-0.2,2
ENSMUSG00000002413,BRAF,Braf transforming gene,nucleus|cytoplasm|mitochondrion|plasma membrane|membrane|neuron projection|neuron projection|cell body|,"MAPK cascade|activation of MAPKK activity|myeloid progenitor cell differentiation|protein phosphorylation|protein phosphorylation|signal transduction|visual learning|positive regulation of gene expression|negative regulation of fibroblast migration|phosphorylation|cell differentiation|positive regulation of peptidyl-serine phosphorylation|somatic stem cell maintenance|intracellular signal transduction|cellular response to drug|regulation of cell proliferation|negative regulation of apoptotic process|CD4-positive, alpha-beta T cell differentiation|positive T cell selection|response to peptide hormone|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|alpha-beta T cell differentiation|protein heterooligomerization|positive regulation of stress fiber assembly|positive regulation of stress fiber assembly|response to cAMP|long-term synaptic potentiation|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cellular response to calcium ion|positive regulation of substrate adhesion-dependent cell spreading|negative regulation of synaptic vesicle exocytosis|negative regulation of endothelial cell apoptotic process|","nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|receptor signaling protein activity|calcium ion binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase binding|identical protein binding|metal ion binding|protein heterodimerization activity|",10,0.2,0.762,10,0.5,2.99,0.5,2.6,2.6,0.296,0,0,-0.6,1.6
ENSMUSG00000040888,GFER,"growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)",cytoplasm|mitochondrion|mitochondrion|,oxidation-reduction process|,growth factor activity|protein disulfide oxidoreductase activity|oxidoreductase activity|thiol oxidase activity|flavin adenine dinucleotide binding|,8,-0.8,3.39,7,0.6,2.81,-0.5,2.6,-2.6,0.296,0,0,-1.9,1.3
ENSMUSG00000066406,AKAP13,A kinase (PRKA) anchor protein 13,cytoplasm|membrane|perinuclear region of cytoplasm|,regulation of cardiac muscle hypertrophy|phosphorylation|regulation of protein kinase activity|nuclear export|regulation of glucocorticoid mediated signaling pathway|,kinase activity|transferase activity|Rho GTPase binding|protein complex scaffold|metal ion binding|protein kinase A binding|,10,0.6,2.54,10,0.3,0.763,0.5,2.56,2.56,0.3,0,0,-0.6,1.7
ENSMUSG00000032050,RDX,radixin,ruffle|extracellular space|cytoplasm|cytoskeleton|plasma membrane|microvillus|microvillus|cell-cell adherens junction|focal adhesion|membrane|extrinsic component of membrane|lamellipodium|filopodium|T-tubule|midbody|cleavage furrow|stereocilium|apical part of cell|cell tip|extracellular vesicular exosome|,positive regulation of gene expression|microvillus assembly|apical protein localization|apical protein localization|barbed-end actin filament capping|actin filament capping|establishment of endothelial barrier|,actin binding|protein binding|cytoskeletal protein binding|poly(A) RNA binding|,9,1.3,5.6,9,-1,4.04,1.3,2.53,2.53,0.303,0,0,-1.9,2.5
ENSMUSG00000004341,GPX6,glutathione peroxidase 6,extracellular region|,response to oxidative stress|oxidation-reduction process|,peroxidase activity|glutathione peroxidase activity|oxidoreductase activity|,9,-0.1,0.302,9,-1,4.69,-0.9,2.53,-2.53,0.303,0,0,-2,0.1
ENSMUSG00000028719,CMPK1,cytidine monophosphate (UMP-CMP) kinase 1,nucleus|nucleolus|cytoplasm|extracellular vesicular exosome|,nucleobase-containing compound metabolic process|nucleoside diphosphate phosphorylation|pyrimidine nucleotide biosynthetic process|UDP biosynthetic process|dUDP biosynthetic process|dCDP biosynthetic process|nucleoside triphosphate biosynthetic process|phosphorylation|CDP biosynthetic process|nucleotide phosphorylation|,"nucleotide binding|cytidylate kinase activity|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, phosphate group as acceptor|nucleotide kinase activity|nucleobase-containing compound kinase activity|UMP kinase activity|",10,-0.3,0.744,10,0.9,5.37,0.8,2.52,2.52,0.304,0,0,-0.4,2
ENSMUSG00000031497,TNFSF13B,"tumor necrosis factor (ligand) superfamily, member 13b",extracellular region|extracellular space|cell|cytoplasm|plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,B cell homeostasis|positive regulation of germinal center formation|immune response|positive regulation of B cell proliferation|T cell costimulation|B cell costimulation|positive regulation of T cell proliferation|immunoglobulin secretion|regulation of immune response|,cytokine activity|tumor necrosis factor receptor binding|,10,0,0,10,-0.7,3.75,-0.4,2.52,-2.52,0.304,0,0,-1.9,0.2
ENSMUSG00000035105,EGLN3,egl-9 family hypoxia-inducible factor 3,nucleus|cytoplasm|cytosol|,response to hypoxia|apoptotic process|cellular response to DNA damage stimulus|protein hydroxylation|peptidyl-proline hydroxylation to 4-hydroxy-L-proline|peptidyl-proline hydroxylation|regulation of cell proliferation|regulation of cell proliferation|regulation of neuron apoptotic process|oxidation-reduction process|,"iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|L-ascorbic acid binding|peptidyl-proline dioxygenase activity|peptidyl-proline 4-dioxygenase activity|metal ion binding|dioxygenase activity|",9,1.1,5.63,9,-0.1,0.538,1,2.51,2.51,0.305,0,0,-0.4,2
ENSMUSG00000031445,PROZ,"protein Z, vitamin K-dependent plasma glycoprotein",extracellular region|extracellular vesicular exosome|,proteolysis|blood coagulation|blood coagulation|hemostasis|,catalytic activity|serine-type endopeptidase activity|calcium ion binding|,10,-0.4,2.56,10,-0.2,0.293,-0.3,2.5,-2.5,0.306,0,0,-1.6,0.6
ENSMUSG00000017740,SLC12A5,"solute carrier family 12, member 5",intracellular|plasma membrane|plasma membrane|membrane|integral component of membrane|dendrite membrane|cell projection|neuronal cell body|dendritic shaft|perikaryon|,transport|ion transport|cation transport|potassium ion transport|chloride transport|chloride transport|synaptic transmission|learning|organic cation transport|ammonium transport|multicellular organism growth|thermosensory behavior|response to drug|intracellular pH reduction|transmembrane transport|ammonium transmembrane transport|chloride transmembrane transport|chloride transmembrane transport|,protein binding|ammonium transmembrane transporter activity|symporter activity|cation:chloride symporter activity|potassium:chloride symporter activity|potassium:chloride symporter activity|protein kinase binding|,10,-0.6,4.25,10,0,0,-0.5,2.5,-2.5,0.306,0,0,-1.7,0.5
ENSMUSG00000024006,STK38,serine/threonine kinase 38,nucleus|cytoplasm|MLL5-L complex|,cellular protein modification process|protein phosphorylation|phosphorylation|intracellular signal transduction|negative regulation of MAP kinase activity|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase kinase binding|metal ion binding|",10,1.5,5.64,10,0.1,0.474,1.5,2.46,2.46,0.31,0,0,0,2.8
ENSMUSG00000018166,ERBB3,v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian),extracellular space|nucleus|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|lateral plasma membrane|receptor complex|postsynaptic membrane|,endocardial cushion development|protein phosphorylation|negative regulation of cell adhesion|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|epidermal growth factor receptor signaling pathway|peripheral nervous system development|negative regulation of signal transduction|Schwann cell differentiation|phosphatidylinositol 3-kinase signaling|phosphorylation|cranial nerve development|regulation of cell proliferation|negative regulation of neuron apoptotic process|positive regulation of glucose import|negative regulation of secretion|neuron apoptotic process|positive regulation of protein tyrosine kinase activity|extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|protein tyrosine kinase activator activity|neuregulin receptor activity|neuregulin binding|protein heterodimerization activity|",10,0.2,1.87,10,-0.4,2.29,0.4,2.4,2.4,0.317,0,0,-0.9,1.7
ENSMUSG00000024027,GLP1R,glucagon-like peptide 1 receptor,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,response to stress|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|learning or memory|learning or memory|memory|feeding behavior|regulation of heart contraction|positive regulation of cell proliferation|associative learning|response to glucose|cAMP-mediated signaling|insulin secretion|positive regulation of insulin secretion|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of cell differentiation|positive regulation of blood pressure|positive regulation of heart contraction|positive regulation of transcription from RNA polymerase II promoter|hormone secretion|release of sequestered calcium ion into cytosol|regulation of calcium ion transport|,peptide receptor activity|signal transducer activity|receptor activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|glucagon receptor activity|G-protein coupled peptide receptor activity|peptide hormone binding|,10,1.2,5.31,10,0,0,0.4,2.4,2.4,0.317,0,0,-0.2,2
ENSMUSG00000079262,SLCO1A6,"solute carrier organic anion transporter family, member 1a6",plasma membrane|membrane|integral component of membrane|,xenobiotic metabolic process|transport|ion transport|bile acid metabolic process|multicellular organism growth|heme metabolic process|response to drug|cholesterol homeostasis|triglyceride homeostasis|,molecular_function|transporter activity|,10,-0.1,0.208,10,0.4,3.45,0.3,2.37,2.37,0.32,0,0,-0.7,1.6
ENSMUSG00000003527,DGCR14,DiGeorge syndrome critical region gene 14,nucleus|spliceosomal complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,None,10,1,4.57,10,0,0,0.5,2.36,2.36,0.321,0,0,-0.2,2
ENSMUSG00000020032,NUAK1,"NUAK family, SNF1-like kinase, 1",nucleus|nucleolus|cytoplasm|microtubule cytoskeleton|,protein phosphorylation|cellular response to DNA damage stimulus|cell adhesion|phosphorylation|regulation of cell adhesion|regulation of myosin-light-chain-phosphatase activity|regulation of cellular senescence|,"nucleotide binding|p53 binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.2,4.89,9,0,0,0.6,2.35,2.35,0.322,0,0,-0.1,2
ENSMUSG00000040147,MAOB,monoamine oxidase B,mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|integral component of membrane|extracellular vesicular exosome|,negative regulation of serotonin secretion|neurotransmitter catabolic process|positive regulation of dopamine metabolic process|oxidation-reduction process|,primary amine oxidase activity|oxidoreductase activity|protein homodimerization activity|flavin adenine dinucleotide binding|,10,-0.4,3.22,10,-0.1,0.108,-0.3,2.34,-2.34,0.324,0,0,-1.6,0.4
ENSMUSG00000034616,SSH3,slingshot homolog 3 (Drosophila),nucleus|cytoplasm|cytoskeleton|,protein dephosphorylation|regulation of actin polymerization or depolymerization|regulation of lamellipodium assembly|dephosphorylation|regulation of axonogenesis|,DNA binding|actin binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,0.1,0.293,10,-0.4,3.03,-0.4,2.34,-2.34,0.324,0,0,-1.5,1.3
ENSMUSG00000030718,PPME1,protein phosphatase methylesterase 1,None,protein demethylation|,catalytic activity|hydrolase activity|protein kinase binding|protein phosphatase binding|protein phosphatase 2A binding|protein C-terminal methylesterase activity|carboxylic ester hydrolase activity|,10,0.5,3.58,10,0.1,0.208,0.3,2.33,2.33,0.325,0,0,-0.5,1.5
ENSMUSG00000020774,ASPA,aspartoacylase,nucleus|cytoplasm|extracellular vesicular exosome|,acetate metabolic process|metabolic process|positive regulation of oligodendrocyte differentiation|,"aminoacylase activity|hydrolase activity|hydrolase activity, acting on ester bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|aspartoacylase activity|metal ion binding|",10,0,0,10,1.1,5.15,1,2.33,2.33,0.325,0,0,-1.5,2
ENSMUSG00000037022,MMAA,methylmalonic aciduria (cobalamin deficiency) type A,cellular_component|mitochondrion|,biological_process|,nucleotide binding|molecular_function|GTP binding|hydrolase activity|,10,-0.4,2.29,10,-0.2,0.548,-0.3,2.33,-2.33,0.325,0,0,-1.6,0.7
ENSMUSG00000028469,NPR2,natriuretic peptide receptor 2,plasma membrane|plasma membrane|membrane|integral component of membrane|,ossification|cGMP biosynthetic process|cGMP biosynthetic process|protein phosphorylation|signal transduction|receptor guanylyl cyclase signaling pathway|cyclic nucleotide biosynthetic process|intracellular signal transduction|single organism reproductive process|negative regulation of meiotic cell cycle|bone development|negative regulation of oocyte maturation|,"nucleotide binding|guanylate cyclase activity|guanylate cyclase activity|protein kinase activity|ATP binding|GTP binding|transferase activity, transferring phosphorus-containing groups|lyase activity|phosphorus-oxygen lyase activity|natriuretic peptide receptor activity|natriuretic peptide receptor activity|peptide hormone binding|hormone binding|identical protein binding|",10,1.1,3.27,10,0.4,0.354,0.4,2.31,2.31,0.327,0,0,0,2
ENSMUSG00000023039,KRT7,keratin 7,nucleus|cytoplasm|intermediate filament|keratin filament|,None,structural molecule activity|protein binding|,10,0.2,0.342,10,0.4,2.97,0.3,2.28,2.28,0.33,0,0,-0.7,1.6
ENSMUSG00000023852,CHD1,chromodomain helicase DNA binding protein 1,nucleus|cytoplasm|,"chromatin assembly or disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|",nucleotide binding|DNA binding|chromatin binding|helicase activity|ATP binding|hydrolase activity|methylated histone binding|,10,1.1,1.28,10,-0.4,2.33,-0.3,2.27,-2.27,0.331,0,0,-1.1,1.9
ENSMUSG00000027088,PHOSPHO2,"phosphatase, orphan 2",cellular_component|,biological_process|metabolic process|,hydrolase activity|phosphatase activity|pyridoxal phosphatase activity|metal ion binding|,10,0.2,0.836,10,0.6,1.95,0.5,2.27,2.27,0.331,0,0,-0.6,1.9
ENSMUSG00000068758,IL3RA,"interleukin 3 receptor, alpha chain",plasma membrane|membrane|integral component of membrane|,None,cytokine receptor activity|,10,0.1,0.101,10,0.4,2.72,0.3,2.24,2.24,0.335,0,0,-0.4,1.7
ENSMUSG00000025355,MMP19,matrix metallopeptidase 19,extracellular region|proteinaceous extracellular matrix|plasma membrane|membrane|extracellular matrix|anchored component of membrane|,angiogenesis|proteolysis|multicellular organismal development|cell differentiation|collagen catabolic process|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0.8,4.65,0.8,2.24,2.24,0.335,0,0,-0.8,2
ENSMUSG00000021794,GLUD1,glutamate dehydrogenase 1,cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|,cellular amino acid metabolic process|glutamate biosynthetic process|glutamate catabolic process|glutamine metabolic process|response to aluminum ion|positive regulation of insulin secretion|positive regulation of insulin secretion|oxidation-reduction process|tricarboxylic acid metabolic process|,nucleotide binding|glutamate dehydrogenase (NAD+) activity|glutamate dehydrogenase [NAD(P)+] activity|glutamate dehydrogenase [NAD(P)+] activity|protein binding|ATP binding|GTP binding|oxidoreductase activity|enzyme binding|ADP binding|NAD+ binding|leucine binding|,10,0.9,5.22,10,0,0,0.9,2.23,2.23,0.336,0,0,-0.6,2
ENSMUSG00000039058,AK5,adenylate kinase 5,cytoplasm|microtubule organizing center|,nucleobase-containing compound metabolic process|nucleoside diphosphate phosphorylation|nucleoside triphosphate biosynthetic process|phosphorylation|ATP metabolic process|,nucleotide binding|adenylate kinase activity|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|nucleobase-containing compound kinase activity|nucleoside kinase activity|,10,0.4,3.55,10,0.1,0.113,0.3,2.23,2.23,0.336,0,0,-0.4,1.8
ENSMUSG00000029471,CAMKK2,"calcium/calmodulin-dependent protein kinase kinase 2, beta",nucleus|cytoplasm|cell projection|,protein phosphorylation|phosphorylation|activation of protein kinase activity|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calcium ion binding|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.208,10,0.3,2.19,0.3,2.22,2.22,0.337,0,0,-0.4,1.7
ENSMUSG00000029674,LIMK1,"LIM-domain containing, protein kinase",nucleus|nucleus|cytoplasm|cytoplasm|Golgi apparatus|focal adhesion|neuron projection|axonal growth cone|perinuclear region of cytoplasm|,protein phosphorylation|phosphorylation|positive regulation of actin filament bundle assembly|positive regulation of axon extension|negative regulation of ubiquitin-protein transferase activity|positive regulation of stress fiber assembly|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|zinc ion binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|heat shock protein binding|metal ion binding|protein heterodimerization activity|",10,0.2,0.121,10,-0.3,3.3,-0.2,2.21,-2.21,0.338,0,0,-1.1,2.8
ENSMUSG00000017376,NLK,nemo like kinase,nucleus|cytoplasm|,"MAPK cascade|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|transforming growth factor beta receptor signaling pathway|Wnt signaling pathway|phosphorylation|peptidyl-threonine phosphorylation|negative regulation of Wnt signaling pathway|serine phosphorylation of STAT3 protein|intracellular signal transduction|protein autophosphorylation|","nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|protein binding|ATP binding|transcription factor binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|ubiquitin protein ligase binding|SH2 domain binding|metal ion binding|",10,0.9,3.16,10,-0.7,1.4,-0.7,2.2,-2.2,0.339,0,0,-1.9,1.3
ENSMUSG00000020553,PCTP,phosphatidylcholine transfer protein,cytoplasm|,transport|lipid transport|cholesterol metabolic process|phospholipid transport|,lipid binding|phosphatidylcholine transporter activity|phosphatidylcholine binding|,10,0.5,1.94,10,0.2,1.06,0.3,2.15,2.15,0.346,0,0,-0.9,1.7
ENSMUSG00000020636,ALLC,allantoicase,cellular_component|,allantoin metabolic process|allantoin catabolic process|,allantoicase activity|hydrolase activity|,10,1.2,3.57,10,-0.3,2.67,-0.3,2.14,-2.14,0.347,0,0,-0.8,2
ENSMUSG00000078429,CTDSP2,"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2",cellular_component|nucleus|,negative regulation of protein phosphorylation|protein dephosphorylation|negative regulation of G1/S transition of mitotic cell cycle|,phosphoprotein phosphatase activity|CTD phosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|,10,0.3,2.21,10,-0.3,3.3,-0.2,2.14,-2.14,0.347,0,0,-1.2,1.1
ENSMUSG00000027419,PCSK2,proprotein convertase subtilisin/kexin type 2,extracellular space|extracellular space|membrane|secretory granule|dendrite|cytoplasmic vesicle|neuronal cell body|perikaryon|,proteolysis|proteolysis|proteolysis|protein processing|peptide hormone processing|peptide hormone processing|peptide hormone processing|protein autoprocessing|insulin processing|enkephalin processing|islet amyloid polypeptide processing|,endopeptidase activity|serine-type endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|protein complex binding|,10,0.4,2.96,10,0.1,0.0872,0.3,2.13,2.13,0.348,0,0,-0.5,1.7
ENSMUSG00000035200,CHRNB4,"cholinergic receptor, nicotinic, beta polypeptide 4",plasma membrane|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|neuron projection|synapse|postsynaptic membrane|,action potential|transport|ion transport|smooth muscle contraction|regulation of smooth muscle contraction|signal transduction|locomotory behavior|response to nicotine|behavioral response to nicotine|regulation of membrane potential|protein heterooligomerization|synaptic transmission involved in micturition|synaptic transmission involved in micturition|synaptic transmission involved in micturition|,acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|drug binding|acetylcholine receptor activity|acetylcholine binding|protein heterodimerization activity|,10,0.8,0.648,10,0.8,1.62,0.8,2.11,2.11,0.35,0,0,-1.8,2
ENSMUSG00000020827,MINK1,misshapen-like kinase 1 (zebrafish),intracellular|cytoplasm|Golgi apparatus|plasma membrane|membrane|cell junction|cell projection|synapse|postsynaptic membrane|extracellular vesicular exosome|,regulation of cell-matrix adhesion|protein phosphorylation|protein phosphorylation|response to stress|synaptic transmission|phosphorylation|regulation of cell-cell adhesion|signal transduction by phosphorylation|regulation of cell migration|actin cytoskeleton reorganization|intracellular signal transduction|intracellular signal transduction|negative thymic T cell selection|positive regulation of JNK cascade|protein autophosphorylation|dendrite morphogenesis|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,2.64,10,0.1,0.456,0.2,2.1,2.1,0.352,0,0,-0.7,1.5
ENSMUSG00000049265,KCNK3,"potassium channel, subfamily K, member 3",plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|ion transmembrane transport|regulation of ion transmembrane transport|response to drug|negative regulation of cytosolic calcium ion concentration|cellular response to hypoxia|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|open rectifier potassium channel activity|potassium channel activity|protein C-terminus binding|potassium ion leak channel activity|protein homodimerization activity|S100 protein binding|protein heterodimerization activity|,10,0,0,10,-0.4,3.96,-0.3,2.1,-2.1,0.352,0,0,-1.6,0.5
ENSMUSG00000043659,NPSR1,neuropeptide S receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|G-protein coupled receptor activity|vasopressin receptor activity|neuropeptide receptor activity|,10,0.3,0.786,10,-0.4,2.42,0.3,2.09,2.09,0.353,0,0,-0.9,1.7
ENSMUSG00000035202,LARS2,"leucyl-tRNA synthetase, mitochondrial",mitochondrion|,translation|tRNA aminoacylation for protein translation|leucyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA editing activity|aminoacyl-tRNA ligase activity|leucine-tRNA ligase activity|ATP binding|ligase activity|,10,0.2,1.41,8,0.4,0.96,0.3,2.09,2.09,0.353,0,0,-1.8,1.3
ENSMUSG00000027790,SIS,sucrase isomaltase (alpha-glucosidase),brush border|brush border|membrane|membrane raft|,metabolic process|,"beta-fructofuranosidase activity|oligo-1,6-glucosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.2,0.711,10,0.7,2.42,0.5,2.07,2.07,0.355,0,0,-0.8,1.8
ENSMUSG00000000420,GALNT1,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1,extracellular region|Golgi apparatus|membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,protein O-linked glycosylation|protein O-linked glycosylation via serine|protein O-linked glycosylation via threonine|,"polypeptide N-acetylgalactosaminyltransferase activity|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|manganese ion binding|metal ion binding|",10,0.3,1.72,10,0.2,0.622,0.3,2.07,2.07,0.355,0,0,-0.9,1.6
ENSMUSG00000025314,PTPRJ,"protein tyrosine phosphatase, receptor type, J",immunological synapse|immunological synapse|plasma membrane|plasma membrane|cell-cell junction|cell surface|membrane|integral component of membrane|cell junction|ruffle membrane|cell projection|extracellular vesicular exosome|,vasculogenesis|positive regulation of cell-matrix adhesion|protein dephosphorylation|heart development|blood coagulation|negative regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of platelet activation|negative regulation of platelet-derived growth factor receptor signaling pathway|negative regulation of platelet-derived growth factor receptor signaling pathway|positive regulation of macrophage chemotaxis|dephosphorylation|regulation of cell adhesion|negative regulation of cell growth|negative regulation of cell migration|negative regulation of cell migration|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of vascular permeability|negative regulation of MAP kinase activity|negative regulation of MAP kinase activity|positive regulation of cell adhesion|platelet-derived growth factor receptor signaling pathway|oligodendrocyte differentiation|negative regulation of T cell receptor signaling pathway|negative regulation of T cell receptor signaling pathway|positive chemotaxis|positive regulation of focal adhesion assembly|positive regulation of protein kinase B signaling|negative regulation of protein kinase B signaling|negative regulation of receptor activity|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|platelet-derived growth factor receptor binding|beta-catenin binding|hydrolase activity|phosphatase activity|protein kinase binding|gamma-catenin binding|mitogen-activated protein kinase binding|delta-catenin binding|,10,1.1,4.58,10,0.1,0.578,0.7,2.06,2.06,0.356,0,0,-0.1,2
ENSMUSG00000006542,PRKAG3,"protein kinase, AMP-activated, gamma 3 non-catatlytic subunit",extracellular space|AMP-activated protein kinase complex|,glycogen biosynthetic process|protein phosphorylation|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|glucose transport|,nucleotide binding|AMP-activated protein kinase activity|ATP binding|protein kinase binding|adenyl nucleotide binding|,10,0.4,1.92,10,0.2,0.611,0.3,2.05,2.05,0.358,0,0,-0.4,1.8
ENSMUSG00000031295,PHKA2,phosphorylase kinase alpha 2,plasma membrane|phosphorylase kinase complex|membrane|,carbohydrate metabolic process|polysaccharide metabolic process|glycogen metabolic process|protein phosphorylation|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|phosphorylase kinase activity|calmodulin binding|",10,-0.5,1.85,10,-0.2,0.864,-0.3,2.03,-2.03,0.36,0,0,-1.7,0.6
ENSMUSG00000026471,MR1,"major histocompatibility complex, class I-related",endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|MHC class I protein complex|,positive regulation of T cell mediated cytotoxicity|cytokine production involved in immune response|immune system process|antigen processing and presentation of peptide antigen via MHC class I|immune response|antigen processing and presentation|interleukin-1 beta production|interleukin-17 production|innate immune response|defense response to Gram-negative bacterium|,peptide antigen binding|,10,-0.3,1.44,10,-0.2,0.774,-0.2,2.03,-2.03,0.36,0,0,-1.4,0.9
ENSMUSG00000027870,HAO2,hydroxyacid oxidase 2,mitochondrion|peroxisome|extracellular vesicular exosome|,mandelate metabolic process|fatty acid oxidation|protein homooligomerization|oxidation-reduction process|,catalytic activity|(S)-2-hydroxy-acid oxidase activity|receptor binding|FMN binding|oxidoreductase activity|very-long-chain-(S)-2-hydroxy-acid oxidase activity|long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity|medium-chain-(S)-2-hydroxy-acid oxidase activity|,10,0,0,10,0.3,2.42,0.3,1.99,1.99,0.365,0,0,-0.5,1.7
ENSMUSG00000028527,AK4,adenylate kinase 4,mitochondrion|mitochondrion|mitochondrial matrix|extracellular vesicular exosome|,nucleobase-containing compound metabolic process|nucleoside diphosphate phosphorylation|nucleoside triphosphate biosynthetic process|phosphorylation|AMP metabolic process|ATP metabolic process|GTP metabolic process|,"nucleotide binding|adenylate kinase activity|nucleoside diphosphate kinase activity|ATP binding|GTP binding|kinase activity|transferase activity|phosphotransferase activity, phosphate group as acceptor|nucleobase-containing compound kinase activity|nucleoside triphosphate adenylate kinase activity|",10,1.1,4.87,10,-0.3,0.282,0.7,1.98,1.98,0.367,0,0,-0.9,2
ENSMUSG00000035594,CHRNA5,"cholinergic receptor, nicotinic, alpha polypeptide 5",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|dendrite|neuronal cell body|synapse|postsynaptic membrane|,transport|ion transport|cation transport|signal transduction|synaptic transmission|ion transmembrane transport|response to nicotine|behavioral response to nicotine|,acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|acetylcholine receptor activity|acetylcholine binding|protein heterodimerization activity|,10,-0.4,1.77,10,-0.1,0.514,-0.3,1.96,-1.96,0.369,0,0,-1.6,0.8
ENSMUSG00000001300,EFNB2,ephrin B2,plasma membrane|membrane|integral component of membrane|,angiogenesis|lymph vessel development|cell migration involved in sprouting angiogenesis|cell adhesion|multicellular organismal development|nervous system development|axon guidance|organ morphogenesis|negative regulation of keratinocyte proliferation|cell migration|cell differentiation|ephrin receptor signaling pathway|ephrin receptor signaling pathway|blood vessel morphogenesis|regulation of chemotaxis|positive regulation of cardiac muscle cell differentiation|,receptor binding|protein binding|ephrin receptor binding|ephrin receptor binding|,9,0.5,0.0896,9,-0.7,4.61,-0.7,1.96,-1.96,0.369,0,0,-2,0.6
ENSMUSG00000015981,STK32C,serine/threonine kinase 32C,cellular_component|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.4,2.85,10,-0.1,0.0877,-0.2,1.95,-1.95,0.371,0,0,-1.6,0.5
ENSMUSG00000029672,FAM3C,"family with sequence similarity 3, member C",extracellular region|Golgi apparatus|cytoplasmic vesicle|extracellular vesicular exosome|,multicellular organismal development|biological_process|,molecular_function|,10,0.4,1.68,10,0.2,0.761,0.3,1.95,1.95,0.371,0,0,-1,1.6
ENSMUSG00000022607,PTK2,PTK2 protein tyrosine kinase 2,nucleus|nucleus|nucleolus|cytoplasm|cytosol|cytoskeleton|plasma membrane|focal adhesion|focal adhesion|intercalated disc|membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|nuclear body|lamellipodium|cell junction|sarcolemma|,MAPK cascade|microtubule cytoskeleton organization|angiogenesis|blood vessel development|vasculogenesis|neuron migration|neuron migration|positive regulation of protein phosphorylation|protein phosphorylation|cellular component movement|signal complex assembly|integrin-mediated signaling pathway|integrin-mediated signaling pathway|JNK cascade|multicellular organismal development|positive regulation of cell proliferation|regulation of cell shape|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of smooth muscle cell migration|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|central nervous system neuron axonogenesis|negative regulation of cell-cell adhesion|extracellular matrix organization|positive regulation of cell growth|positive regulation of cell migration|negative regulation of cell migration|cellular chloride ion homeostasis|regulation of cell adhesion mediated by integrin|establishment of nucleus localization|regulation of cell proliferation|negative regulation of apoptotic process|endothelial cell migration|regulation of osteoblast differentiation|positive regulation of cell adhesion|positive regulation of protein kinase activity|positive regulation of vasodilation|negative regulation of organ growth|protein autophosphorylation|protein autophosphorylation|protein autophosphorylation|ephrin receptor signaling pathway|positive regulation of smooth muscle cell proliferation|positive regulation of phagocytosis|negative regulation of axonogenesis|positive regulation of synaptic transmission|positive regulation of protein kinase B signaling|negative regulation of synapse assembly|positive regulation of glial cell proliferation|growth hormone receptor signaling pathway|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of anoikis|,"nucleotide binding|actin binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|signal transducer activity|integrin binding|protein binding|ATP binding|JUN kinase binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein complex binding|SH2 domain binding|identical protein binding|phosphatidylinositol 3-kinase binding|",10,-0.3,1.73,10,-0.2,0.515,-0.3,1.95,-1.95,0.371,0,0,-1.6,0.5
ENSMUSG00000034055,PHKA1,phosphorylase kinase alpha 1,plasma membrane|phosphorylase kinase complex|membrane|,carbohydrate metabolic process|polysaccharide metabolic process|glycogen metabolic process|protein autophosphorylation|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|phosphorylase kinase activity|calmodulin binding|",10,-0.3,1.08,10,-0.3,1.02,-0.3,1.94,-1.94,0.372,0,0,-1.5,1
ENSMUSG00000029147,PPM1G,"protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform",nucleus|nucleus|,protein dephosphorylation|cell cycle|cell cycle arrest|peptidyl-threonine dephosphorylation|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein binding|hydrolase activity|metal ion binding|,10,0,0,10,0.4,2.69,0.4,1.94,1.94,0.372,0,0,-0.3,1.8
ENSMUSG00000022756,SLC7A4,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 4",membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|biological_process|,molecular_function|amino acid transmembrane transporter activity|,10,-0.4,2.79,10,0,0,-0.3,1.92,-1.92,0.375,0,0,-1.6,0.7
ENSMUSG00000020250,TXNRD1,thioredoxin reductase 1,nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|cytosol|cytosol|neuronal cell body|,mesoderm formation|response to oxidative stress|gastrulation|cell proliferation|positive regulation of cell death|selenocysteine metabolic process|benzene-containing compound metabolic process|hydrogen peroxide catabolic process|cell redox homeostasis|protein tetramerization|oxidation-reduction process|NADPH oxidation|,"thioredoxin-disulfide reductase activity|thioredoxin-disulfide reductase activity|NAD(P)H oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor|selenate reductase activity|protein homodimerization activity|mercury ion binding|flavin adenine dinucleotide binding|NADP binding|",10,0,0,10,-0.3,3.58,-0.3,1.92,-1.92,0.375,0,0,-1.5,0.8
ENSMUSG00000073876,GM13305,predicted gene 13305,cellular_component|,None,molecular_function|,10,-0.8,1.1,10,0.5,2.72,0.3,1.91,1.91,0.376,0,0,-1.6,1.4
ENSMUSG00000078735,IL11RA2,"interleukin 11 receptor, alpha chain 2",None,None,None,10,-0.8,1.1,10,0.5,2.72,0.3,1.91,1.91,0.376,0,0,-1.6,1.4
ENSMUSG00000037318,TRAF3IP3,TRAF3 interacting protein 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.587,10,-0.7,2.31,0.5,1.87,1.87,0.381,0,0,-1.4,1.7
ENSMUSG00000026643,NMT2,N-myristoyltransferase 2,cytoplasm|cytoplasm|Golgi apparatus|plasma membrane|,N-terminal protein myristoylation|N-terminal peptidyl-glycine N-myristoylation|,"glycylpeptide N-tetradecanoyltransferase activity|glycylpeptide N-tetradecanoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.1,0.489,10,-0.6,3.21,-0.4,1.86,-1.86,0.382,0,0,-1.8,0.5
ENSMUSG00000029247,PAICS,"phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase",membrane|extracellular vesicular exosome|,purine nucleotide biosynthetic process|'de novo' IMP biosynthetic process|metabolic process|,nucleotide binding|catalytic activity|phosphoribosylaminoimidazole carboxylase activity|phosphoribosylaminoimidazolesuccinocarboxamide synthase activity|ATP binding|lyase activity|carboxy-lyase activity|ligase activity|identical protein binding|,2,0.5,1.05,3,0.3,1.15,0.5,1.86,1.86,0.382,0,0,-1.3,2
ENSMUSG00000050965,PRKCA,"protein kinase C, alpha",photoreceptor outer segment|intracellular|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|endoplasmic reticulum|cytosol|plasma membrane|plasma membrane|membrane|dendrite|neuron projection|neuronal cell body|protein complex|membrane raft|apical part of cell|perinuclear region of cytoplasm|extracellular vesicular exosome|,inactivation of MAPK activity|response to reactive oxygen species|angiogenesis|negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|regulation of the force of heart contraction|chondrocyte differentiation|desmosome assembly|protein phosphorylation|protein phosphorylation|negative regulation of protein kinase activity|cellular calcium ion homeostasis|apoptotic process|regulation of muscle contraction|cell adhesion|learning or memory|negative regulation of cell proliferation|positive regulation of endothelial cell migration|positive regulation of cardiac muscle hypertrophy|phosphorylation|negative regulation of translation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|central nervous system neuron axonogenesis|positive regulation of cell migration|neutrophil chemotaxis|positive regulation of lipopolysaccharide-mediated signaling pathway|response to estradiol|negative regulation of glial cell apoptotic process|histone H3-T6 phosphorylation|intracellular signal transduction|peptidyl-serine autophosphorylation|positive regulation of blood vessel endothelial cell migration|response to ethanol|positive regulation of macrophage differentiation|positive regulation of angiogenesis|positive regulation of cell adhesion|negative regulation of heart contraction|positive regulation of exocytosis|positive regulation of mitotic cell cycle|negative regulation of glucose import|negative regulation of insulin receptor signaling pathway|protein autophosphorylation|regulation of receptor-mediated endocytosis|positive regulation of smooth muscle cell proliferation|positive regulation of inflammatory response|regulation of peptidyl-tyrosine phosphorylation|induction of positive chemotaxis|positive regulation of synapse assembly|positive regulation of ERK1 and ERK2 cascade|response to interleukin-1|cellular response to carbohydrate stimulus|regulation of platelet aggregation|regulation of platelet aggregation|intrinsic apoptotic signaling pathway|positive regulation of dense core granule biogenesis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein kinase C activity|calcium-dependent protein kinase C activity|calcium-dependent protein kinase C activity|protein binding|ATP binding|zinc ion binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|histone kinase activity (H3-T6 specific)|metal ion binding|",10,-0.3,1.09,10,-0.2,0.94,-0.3,1.85,-1.85,0.384,0,0,-1.4,1.2
ENSMUSG00000040659,EFHD2,EF hand domain containing 2,membrane|,None,calcium ion binding|protein binding|metal ion binding|,10,-0.3,1.98,10,0.7,2.81,0.7,1.83,1.83,0.386,0,0,-0.8,1.9
ENSMUSG00000032534,CEP63,centrosomal protein 63,cytoplasm|centrosome|centriole|cytoskeleton|,cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|centriole replication|cell division|,protein binding|,10,0.2,0.531,10,0.2,1.44,0.2,1.83,1.83,0.386,0,0,-1.1,1.4
ENSMUSG00000024104,FAM21,family with sequence similarity 21,endosome|early endosome|membrane|WASH complex|,transport|,molecular_function|,9,-0.3,0.824,10,1.3,4.28,1.2,1.82,1.82,0.388,0,0,-0.5,2
ENSMUSG00000029123,STK32B,serine/threonine kinase 32B,None,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.2,1.25,10,0.1,0.811,0.2,1.82,1.82,0.388,0,0,-1.3,1.3
ENSMUSG00000032034,KCNJ5,"potassium inwardly-rectifying channel, subfamily J, member 5",external side of plasma membrane|membrane|integral component of membrane|T-tubule|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|G-protein activated inward rectifier potassium channel activity|,9,0.1,0.0523,9,0.3,1.94,0.3,1.82,1.82,0.388,0,0,-0.8,1.7
ENSMUSG00000034135,SIK3,SIK family kinase 3,cytoplasm|,endochondral ossification|protein phosphorylation|phosphorylation|regulation of protein localization|limb morphogenesis|multicellular organism growth|skeletal system morphogenesis|cartilage development involved in endochondral bone morphogenesis|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",6,0.7,1.52,7,0.3,0.569,0.3,1.81,1.81,0.389,0,0,-0.6,2
ENSMUSG00000027335,ADRA1D,"adrenergic receptor, alpha 1d",cytosol|plasma membrane|membrane|integral component of membrane|,negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure|norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure|signal transduction|G-protein coupled receptor signaling pathway|aging|positive regulation of vasoconstriction|micturition|adrenergic receptor signaling pathway|adrenergic receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|alpha1-adrenergic receptor activity|alpha1-adrenergic receptor activity|,10,-0.5,2.79,10,0.6,1.07,-0.3,1.81,-1.81,0.389,0,0,-1.6,1.3
ENSMUSG00000022857,TMPRSS15,"transmembrane protease, serine 15",membrane|integral component of membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,0.3,1.26,9,0.2,0.71,0.3,1.78,1.78,0.393,0,0,-0.6,1.8
ENSMUSG00000024587,NARS,asparaginyl-tRNA synthetase,cytoplasm|mitochondrion|extracellular vesicular exosome|,translation|tRNA aminoacylation for protein translation|asparaginyl-tRNA aminoacylation|,nucleotide binding|nucleic acid binding|aminoacyl-tRNA ligase activity|asparagine-tRNA ligase activity|ATP binding|ligase activity|,2,0,0,3,0.4,2.45,0.3,1.76,1.76,0.396,0,0,-1.4,2
ENSMUSG00000037624,KCNK2,"potassium channel, subfamily K, member 2",endoplasmic reticulum|plasma membrane|plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|G-protein coupled receptor signaling pathway|stabilization of membrane potential|regulation of ion transmembrane transport|regulation of membrane potential|potassium ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|protein binding|outward rectifier potassium channel activity|potassium channel inhibitor activity|potassium ion leak channel activity|,10,-0.6,2.47,10,-0.2,0.273,-0.3,1.76,-1.76,0.396,0,0,-1.3,1.8
ENSMUSG00000020857,NME2,NME/NM23 nucleoside diphosphate kinase 2,ruffle|nucleus|cytoplasm|mitochondrion|intermediate filament|plasma membrane|membrane|lamellipodium|mitochondrial membrane|cell projection|perinuclear region of cytoplasm|extracellular vesicular exosome|cell periphery|,negative regulation of myeloid leukocyte differentiation|nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|integrin-mediated signaling pathway|nucleotide metabolic process|nucleoside triphosphate biosynthetic process|positive regulation of neuron projection development|phosphorylation|positive regulation of cAMP biosynthetic process|negative regulation of apoptotic process|positive regulation of keratinocyte differentiation|regulation of epidermis development|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|positive regulation of epithelial cell proliferation|protein oligomerization|,nucleotide binding|nucleoside diphosphate kinase activity|protein histidine kinase activity|protein serine/threonine kinase activity|fatty acid binding|protein binding|ATP binding|drug binding|kinase activity|transferase activity|intermediate filament binding|enzyme binding|metal ion binding|,10,0.3,2.88,10,-0.8,1.94,0.3,1.76,1.76,0.396,0,0,-2,0.7
ENSMUSG00000054986,SEC14L3,SEC14-like 3 (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0.3,1.51,10,0.4,0.325,0.3,1.71,1.71,0.403,0,0,-0.5,1.8
ENSMUSG00000031377,BMX,BMX non-receptor tyrosine kinase,cytoplasm|ruffle membrane|,protein phosphorylation|apoptotic process|cell adhesion|signal transduction|phosphorylation|peptidyl-tyrosine phosphorylation|intracellular signal transduction|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",9,0,0,9,-0.3,2.91,-0.3,1.71,-1.71,0.403,0,0,-1.6,1
ENSMUSG00000078799,SULT2A5,"sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5",cellular_component|cytoplasm|cytosol|,biological_process|,alcohol sulfotransferase activity|drug binding|sulfotransferase activity|transferase activity|3'-phosphoadenosine 5'-phosphosulfate binding|,9,-0.4,2.74,9,0,0,-0.3,1.71,-1.71,0.403,0,0,-1.7,0.7
ENSMUSG00000062960,KDR,kinase insert domain protein receptor,extracellular region|nucleus|cytoplasm|endosome|early endosome|Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|neuron projection|neuronal cell body|membrane raft|cell periphery|sorting endosome|,angiogenesis|ovarian follicle development|vasculogenesis|response to hypoxia|positive regulation of protein phosphorylation|regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|lymph vessel development|cell migration involved in sprouting angiogenesis|positive regulation of mesenchymal cell proliferation|endocardium development|endothelium development|endochondral bone growth|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of cytosolic calcium ion concentration|multicellular organismal development|positive regulation of cell proliferation|regulation of cell shape|male gonad development|positive regulation of endothelial cell migration|positive regulation of endothelial cell migration|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|cell migration|peptidyl-tyrosine phosphorylation|hemopoiesis|cell differentiation|lung development|positive regulation of cell migration|positive regulation of BMP signaling pathway|positive regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of TOR signaling|embryonic hemopoiesis|calcium-mediated signaling using intracellular calcium source|cellular response to vascular endothelial growth factor stimulus|peptidyl-tyrosine autophosphorylation|vascular endothelial growth factor signaling pathway|vascular endothelial growth factor signaling pathway|response to drug|negative regulation of apoptotic process|surfactant homeostasis|positive regulation of MAPK cascade|negative regulation of neuron apoptotic process|cell fate commitment|endothelial cell differentiation|endothelial cell differentiation|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of vasodilation|protein autophosphorylation|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|positive regulation of long-term neuronal synaptic plasticity|lung alveolus development|cell maturation|branching morphogenesis of an epithelial tube|neuron projection morphogenesis|positive regulation of epithelial cell proliferation|positive regulation of calcium-mediated signaling|positive regulation of positive chemotaxis|positive regulation of nitric-oxide synthase biosynthetic process|positive regulation of focal adhesion assembly|calcium ion homeostasis|blood vessel endothelial cell differentiation|positive regulation of ERK1 and ERK2 cascade|negative regulation of endothelial cell apoptotic process|positive regulation of vasculogenesis|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|vascular endothelial growth factor-activated receptor activity|vascular endothelial growth factor-activated receptor activity|integrin binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|growth factor binding|vascular endothelial growth factor binding|",10,0.5,2.85,10,0.1,0.0369,0.2,1.7,1.7,0.404,0,0,-0.5,1.7
ENSMUSG00000028788,PTP4A2,protein tyrosine phosphatase 4a2,cytoplasm|endosome|plasma membrane|membrane|extracellular vesicular exosome|,protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,9,0.3,2.22,9,0.1,0.00236,0.3,1.69,1.69,0.406,0,0,-0.9,1.6
ENSMUSG00000052889,PRKCB,"protein kinase C, beta",nucleus|nucleus|cytoplasm|cytoplasm|centrosome|cytosol|plasma membrane|membrane|brush border membrane|extracellular vesicular exosome|,"immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|protein phosphorylation|calcium ion transport|cellular calcium ion homeostasis|apoptotic process|negative regulation of glucose transport|regulation of dopamine secretion|phosphorylation|chromatin modification|positive regulation of vascular endothelial growth factor receptor signaling pathway|histone H3-T6 phosphorylation|intracellular signal transduction|regulation of growth|B cell activation|response to drug|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of angiogenesis|negative regulation of insulin receptor signaling pathway|B cell receptor signaling pathway|positive regulation of B cell receptor signaling pathway|positive regulation of NF-kappaB transcription factor activity|cellular response to carbohydrate stimulus|","nucleotide binding|chromatin binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein kinase C activity|protein kinase C binding|calcium channel regulator activity|protein binding|ATP binding|zinc ion binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|ligand-dependent nuclear receptor transcription coactivator activity|histone kinase activity (H3-T6 specific)|histone binding|metal ion binding|androgen receptor binding|",10,0.1,0.0963,10,-0.4,3.28,-0.3,1.69,-1.69,0.406,0,0,-1.8,0.5
ENSMUSG00000028378,PTGR1,prostaglandin reductase 1,cytoplasm|extracellular vesicular exosome|,oxidation-reduction process|,"zinc ion binding|oxidoreductase activity|enoyl-[acyl-carrier-protein] reductase activity|2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity|cis-2,3-dihydrodiol DDT dehydrogenase activity|trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity|cis-chlorobenzene dihydrodiol dehydrogenase activity|2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity|trans-1,2-dihydrodiolphenanthrene dehydrogenase activity|2-alkenal reductase [NAD(P)] activity|3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity|benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity|benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity|citronellyl-CoA dehydrogenase activity|menthone dehydrogenase activity|phthalate 3,4-cis-dihydrodiol dehydrogenase activity|13-prostaglandin reductase activity|cinnamate reductase activity|15-oxoprostaglandin 13-oxidase activity|NADPH-dependent curcumin reductase activity|NADPH-dependent dihydrocurcumin reductase activity|",10,0.2,1.09,10,0.2,0.717,0.2,1.67,1.67,0.409,0,0,-0.9,1.5
ENSMUSG00000022453,NAGA,"N-acetyl galactosaminidase, alpha",cytoplasm|lysosome|extracellular vesicular exosome|,carbohydrate metabolic process|metabolic process|oligosaccharide metabolic process|carbohydrate catabolic process|glycoside catabolic process|glycolipid catabolic process|glycosylceramide catabolic process|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-galactosidase activity|alpha-N-acetylgalactosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|protein homodimerization activity|",10,-0.4,2.16,10,-0.1,0.179,-0.2,1.65,-1.65,0.412,0,0,-1.3,1.2
ENSMUSG00000059326,CSF2RA,"colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)",membrane|integral component of membrane|,None,cytokine receptor activity|,9,-0.1,0.0445,9,0.4,2.36,0.3,1.64,1.64,0.413,0,0,-0.9,1.7
ENSMUSG00000017412,CACNB4,"calcium channel, voltage-dependent, beta 4 subunit",plasma membrane|voltage-gated calcium channel complex|voltage-gated calcium channel complex|voltage-gated calcium channel complex|synapse|,"transport|ion transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|gamma-aminobutyric acid signaling pathway|neuromuscular junction development|adult walking behavior|gamma-aminobutyric acid secretion|neuronal action potential propagation|regulation of ion transmembrane transport|synaptic transmission, glutamatergic|regulation of membrane potential|cAMP metabolic process|spleen development|thymus development|Peyer's patch development|muscle fiber development|T cell receptor signaling pathway|neurological system process|detection of light stimulus involved in visual perception|calcium ion transmembrane transport|calcium ion transmembrane transport|regulation of voltage-gated calcium channel activity|",voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|protein kinase binding|,10,0.2,0.193,10,0.8,2.79,0.6,1.64,1.64,0.413,0,0,-0.4,1.9
ENSMUSG00000073435,NME3,NME/NM23 nucleoside diphosphate kinase 3,mitochondrion|extracellular vesicular exosome|,nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|nucleotide metabolic process|phosphorylation|,nucleotide binding|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|metal ion binding|,10,0.3,2,10,0.1,0.299,0.2,1.62,1.62,0.416,0,0,-1,1.6
ENSMUSG00000031672,GOT2,"glutamatic-oxaloacetic transaminase 2, mitochondrial",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|plasma membrane|cell surface|membrane|perikaryon|protein complex|extracellular vesicular exosome|,oxaloacetate metabolic process|cellular amino acid metabolic process|aspartate metabolic process|aspartate biosynthetic process|aspartate catabolic process|transport|lipid transport|biosynthetic process|glutamate catabolic process to aspartate|glutamate catabolic process to 2-oxoglutarate|dicarboxylic acid metabolic process|response to ethanol|,catalytic activity|L-aspartate:2-oxoglutarate aminotransferase activity|L-aspartate:2-oxoglutarate aminotransferase activity|phospholipid binding|transaminase activity|kynurenine-oxoglutarate transaminase activity|amino acid binding|transferase activity|enzyme binding|pyridoxal phosphate binding|carboxylic acid binding|protein homodimerization activity|poly(A) RNA binding|L-phenylalanine:2-oxoglutarate aminotransferase activity|,10,0.3,3.26,10,0,0,0.2,1.61,1.61,0.417,0,0,-1,1.5
ENSMUSG00000028111,CTSK,cathepsin K,extracellular space|cytoplasm|lysosome|,proteolysis|collagen catabolic process|bone resorption|proteolysis involved in cellular protein catabolic process|,fibronectin binding|cysteine-type endopeptidase activity|collagen binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|proteoglycan binding|,10,-0.4,3.88,10,0.2,0.437,-0.4,1.61,-1.61,0.417,0,0,-1.7,0.8
ENSMUSG00000030830,ITGAL,integrin alpha L,immunological synapse|cell-cell junction|integrin complex|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|cell adhesion|heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|leukocyte cell-cell adhesion|leukocyte cell-cell adhesion|cell surface receptor signaling pathway|integrin-mediated signaling pathway|single organismal cell-cell adhesion|regulation of cell-cell adhesion|positive regulation of cell-cell adhesion|positive regulation of T cell proliferation|activated T cell proliferation|positive regulation of calcium-mediated signaling|,protein complex binding|metal ion binding|protein heterodimerization activity|cell adhesion molecule binding|,10,0.3,0.621,10,0.4,1.26,0.3,1.6,1.6,0.419,0,0,-0.9,1.7
ENSMUSG00000039145,CAMK1D,calcium/calmodulin-dependent protein kinase ID,nucleus|cytoplasm|,protein phosphorylation|inflammatory response|nervous system development|metabolic process|positive regulation of neuron projection development|phosphorylation|positive regulation of CREB transcription factor activity|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of phagocytosis|regulation of dendrite development|positive regulation of respiratory burst|regulation of granulocyte chemotaxis|positive regulation of neutrophil chemotaxis|,"nucleotide binding|catalytic activity|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.4,1.47,10,-0.2,0.678,-0.3,1.58,-1.58,0.422,0,0,-1.3,1.8
ENSMUSG00000032615,NT5M,"5',3'-nucleotidase, mitochondrial",mitochondrion|mitochondrion|,nucleotide metabolic process|deoxyribonucleotide catabolic process|dephosphorylation|dephosphorylation|dUMP catabolic process|,"nucleotide binding|protein tyrosine/serine/threonine phosphatase activity|5'-nucleotidase activity|5'-nucleotidase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|metal ion binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0.4,3.04,10,0,0,0.4,1.57,1.57,0.424,0,0,-0.7,1.7
ENSMUSG00000017453,PIPOX,pipecolic acid oxidase,peroxisome|peroxisome|,L-lysine catabolic process to acetyl-CoA via L-pipecolate|L-lysine catabolic process to acetyl-CoA via L-pipecolate|tetrahydrofolate metabolic process|oxidation-reduction process|oxidation-reduction process|,receptor binding|sarcosine oxidase activity|sarcosine oxidase activity|oxidoreductase activity|L-pipecolate oxidase activity|L-pipecolate oxidase activity|,10,0.6,2.38,10,0.1,0.0359,0.2,1.56,1.56,0.425,0,0,-0.9,1.6
ENSMUSG00000029053,PRKCZ,"protein kinase C, zeta",nucleus|nuclear envelope|cytoplasm|cytoplasm|endosome|microtubule organizing center|cytosol|plasma membrane|plasma membrane|cell-cell junction|tight junction|cell cortex|apical plasma membrane|nuclear matrix|cell junction|cell leading edge|filamentous actin|myelin sheath abaxonal region|axon hillock|intracellular membrane-bounded organelle|protein complex|protein complex|membrane raft|apical cortex|perinuclear region of cytoplasm|extracellular vesicular exosome|,microtubule cytoskeleton organization|microtubule cytoskeleton organization|positive regulation of cell-matrix adhesion|protein phosphorylation|protein phosphorylation|inflammatory response|signal transduction|cell surface receptor signaling pathway|long-term memory|positive regulation of cell proliferation|insulin receptor signaling pathway|phosphorylation|cell migration|peptidyl-serine phosphorylation|establishment of cell polarity|negative regulation of protein complex assembly|actin cytoskeleton reorganization|activation of phospholipase D activity|activation of protein kinase B activity|positive regulation of interleukin-4 production|cellular response to insulin stimulus|cellular protein localization|intracellular signal transduction|negative regulation of apoptotic process|positive regulation of T-helper 2 cell differentiation|positive regulation of glucose import|negative regulation of insulin receptor signaling pathway|positive regulation of insulin receptor signaling pathway|vesicle transport along microtubule|negative regulation of peptidyl-tyrosine phosphorylation|positive regulation of synaptic transmission|positive regulation of NF-kappaB transcription factor activity|positive regulation of protein transport|protein heterooligomerization|negative regulation of hydrolase activity|membrane depolarization|membrane hyperpolarization|long-term synaptic potentiation|positive regulation of ERK1 and ERK2 cascade|protein kinase C signaling|protein localization to plasma membrane|neuron projection extension|positive regulation of excitatory postsynaptic membrane potential|positive regulation of T-helper 2 cell cytokine production|positive regulation of interleukin-5 secretion|positive regulation of interleukin-13 secretion|positive regulation of interleukin-10 secretion|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein binding|ATP binding|zinc ion binding|potassium channel regulator activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein domain specific binding|phospholipase binding|metal ion binding|14-3-3 protein binding|",10,1.1,1.71,10,0.2,1.99,0.2,1.55,1.55,0.427,0,0,-0.6,2
ENSMUSG00000002908,KCNN1,"potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1",cytoplasm|plasma membrane|membrane|integral component of membrane|neuronal cell body|neuronal cell body|,transport|ion transport|potassium ion transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,calmodulin binding|calcium-activated potassium channel activity|small conductance calcium-activated potassium channel activity|small conductance calcium-activated potassium channel activity|protein heterodimerization activity|,10,-0.2,0.488,10,0.7,3.77,0.6,1.54,1.54,0.428,0,0,-0.8,1.9
ENSMUSG00000024798,HTR7,5-hydroxytryptamine (serotonin) receptor 7,rough endoplasmic reticulum|plasma membrane|synaptic vesicle|membrane|integral component of membrane|dendrite|neuronal cell body|axon terminus|,"smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating serotonin receptor signaling pathway|serotonin receptor signaling pathway|synaptic transmission|memory|circadian rhythm|positive regulation of neuron projection development|negative regulation of serotonin secretion|urinary bladder smooth muscle contraction|vasoconstriction|negative regulation of circadian sleep/wake cycle, REM sleep|behavioral response to pain|detection of mechanical stimulus involved in sensory perception of pain|response to corticosterone|micturition|long-term synaptic potentiation|dopaminergic neuron differentiation|",signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|neurotransmitter receptor activity|,10,0.5,2.75,10,-0.1,0.12,0.4,1.53,1.53,0.43,0,0,-1.5,1.7
ENSMUSG00000018459,SLC13A3,"solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3",plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|dicarboxylic acid transport|dicarboxylic acid transport|succinate transport|citrate transport|aspartate transport|tricarboxylic acid transmembrane transport|sodium ion transmembrane transport|transmembrane transport|succinate transmembrane transport|L-alpha-amino acid transmembrane transport|,transporter activity|dicarboxylic acid transmembrane transporter activity|organic acid:sodium symporter activity|citrate transmembrane transporter activity|succinate transmembrane transporter activity|L-aspartate transmembrane transporter activity|symporter activity|high affinity sodium:dicarboxylate symporter activity|sodium:dicarboxylate symporter activity|,10,-0.1,0.0971,10,-0.4,1.75,-0.2,1.53,-1.53,0.43,0,0,-1.6,0.8
ENSMUSG00000019558,SLC6A8,"solute carrier family 6 (neurotransmitter transporter, creatine), member 8",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|neurotransmitter transport|choline transport|creatine transport|creatine transport|sodium ion transmembrane transport|cofactor transport|creatine transmembrane transport|creatine transmembrane transport|,creatine transmembrane transporter activity|creatine transmembrane transporter activity|creatine:sodium symporter activity|neurotransmitter:sodium symporter activity|choline transmembrane transporter activity|symporter activity|,10,1.6,4.55,10,0.2,0.651,1.6,1.53,1.53,0.43,0,0,-0.2,3
ENSMUSG00000095400,MUC2,mucin 2,extracellular region|proteinaceous extracellular matrix|inner mucus layer|outer mucus layer|,epithelial cell development|apoptotic process|negative regulation of cell proliferation|maintenance of gastrointestinal epithelium|negative regulation of cell migration|positive regulation of apoptotic process|,protein binding|,10,-0.2,0.792,10,-0.3,0.895,-0.2,1.52,-1.52,0.431,0,0,-1.7,0.7
ENSMUSG00000028672,HMGCL,3-hydroxy-3-methylglutaryl-Coenzyme A lyase,mitochondrion|mitochondrion|mitochondrial inner membrane|peroxisome|,acyl-CoA metabolic process|mitochondrion organization|embryo development|ketone body biosynthetic process|protein tetramerization|,fatty-acyl-CoA binding|magnesium ion binding|catalytic activity|hydroxymethylglutaryl-CoA lyase activity|receptor binding|lyase activity|manganese ion binding|carboxylic acid binding|protein homodimerization activity|metal ion binding|,10,1.8,4.99,10,0,0,1.8,1.52,1.52,0.431,0,0,-0.7,3
ENSMUSG00000034793,G6PC3,"glucose 6 phosphatase, catalytic, 3",endoplasmic reticulum|membrane|membrane|integral component of membrane|,gluconeogenesis|phosphate-containing compound metabolic process|glucose-6-phosphate transport|dephosphorylation|dephosphorylation|glucose 6-phosphate metabolic process|,catalytic activity|glucose-6-phosphatase activity|glucose-6-phosphatase activity|glucose-6-phosphatase activity|hydrolase activity|,10,0.4,1.62,10,-0.2,1.66,0.4,1.51,1.51,0.433,0,0,-1.2,1.3
ENSMUSG00000021591,GLRX,glutaredoxin,nucleus|cytoplasm|mitochondrion|extracellular vesicular exosome|,transport|cell redox homeostasis|oxidation-reduction process|,electron carrier activity|protein disulfide oxidoreductase activity|protein-disulfide reductase (glutathione) activity|protein N-terminus binding|,10,0,0,10,-0.4,2.27,-0.2,1.5,-1.5,0.435,0,0,-1.8,0.7
ENSMUSG00000040522,TLR8,toll-like receptor 8,intracellular|membrane|integral component of membrane|,microglial cell activation|toll-like receptor signaling pathway|immune system process|MyD88-dependent toll-like receptor signaling pathway|inflammatory response|signal transduction|I-kappaB kinase/NF-kappaB signaling|response to virus|toll-like receptor 8 signaling pathway|positive regulation of interferon-gamma biosynthetic process|innate immune response|positive regulation of innate immune response|positive regulation of interferon-alpha biosynthetic process|positive regulation of interferon-beta biosynthetic process|positive regulation of interleukin-8 biosynthetic process|regulation of cytokine secretion|defense response to virus|,DNA binding|double-stranded RNA binding|single-stranded RNA binding|drug binding|,10,-0.3,1.11,10,-0.2,0.567,-0.2,1.49,-1.49,0.437,0,0,-1.7,0.6
ENSMUSG00000021477,CTSL,cathepsin L,extracellular space|nucleus|nucleolus|cytoplasm|lysosome|lysosome|vacuole|microvillus|external side of plasma membrane|secretory granule|cytoplasmic vesicle|neuron projection|perikaryon|apical part of cell|extracellular vesicular exosome|,proteolysis|proteolysis|cell communication|negative regulation of keratinocyte proliferation|protein processing|protein processing|protein autoprocessing|hair follicle morphogenesis|catagen|decidualization|regulation of actin cytoskeleton reorganization|,aminopeptidase activity|cysteine-type endopeptidase activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|cysteine-type carboxypeptidase activity|kininogen binding|protein complex binding|peptide binding|histone binding|,10,0.1,0.353,10,0.2,1.51,0.2,1.49,1.49,0.437,0,0,-1.2,1.4
ENSMUSG00000021044,ADCK1,aarF domain containing kinase 1,extracellular region|mitochondrion|,protein phosphorylation|biological_process|phosphorylation|,"nucleotide binding|molecular_function|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|ATP binding|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,1.8,5.03,10,-0.1,0.0832,1.8,1.49,1.49,0.437,0,0,-0.2,3
ENSMUSG00000021196,PFKP,"phosphofructokinase, platelet",nucleus|cytoplasm|cytosol|6-phosphofructokinase complex|membrane|extracellular vesicular exosome|,"fructose 6-phosphate metabolic process|glycolytic process|glycolytic process|metabolic process|phosphorylation|fructose 1,6-bisphosphate metabolic process|carbohydrate phosphorylation|carbohydrate phosphorylation|protein homotetramerization|",nucleotide binding|catalytic activity|6-phosphofructokinase activity|6-phosphofructokinase activity|ATP binding|kinase activity|transferase activity|protein complex binding|metal ion binding|fructose-6-phosphate binding|,10,1.3,4.4,10,0.1,0.479,0.5,1.48,1.48,0.439,0,0,-0.1,2
ENSMUSG00000029022,MIIP,migration and invasion inhibitory protein,cellular_component|,biological_process|,molecular_function|,10,0.4,2.56,10,-0.2,1.35,0.3,1.48,1.48,0.439,0,0,-1.1,1.4
ENSMUSG00000098470,C1RB,"complement component 1, r subcomponent B",extracellular region|blood microparticle|,"immune system process|proteolysis|complement activation|complement activation, classical pathway|innate immune response|",catalytic activity|serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.757,10,0.6,1.5,0.6,1.47,1.47,0.44,0,0,-0.6,1.9
ENSMUSG00000040268,PLEKHA1,"pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1",nucleus|cytoplasm|plasma membrane|membrane|ruffle membrane|extracellular vesicular exosome|,luteinization|spermatogenesis|androgen metabolic process|estrogen metabolic process|female gonad development|post-embryonic development|phosphatidylinositol 3-kinase signaling|ruffle organization|Leydig cell differentiation|multicellular organism growth|establishment of protein localization|platelet-derived growth factor receptor signaling pathway|skeletal system morphogenesis|B cell receptor signaling pathway|negative regulation of protein kinase B signaling|palate development|face morphogenesis|cellular response to hydrogen peroxide|,"lipid binding|PDZ domain binding|phosphatidylinositol-3,4-bisphosphate binding|",8,-0.2,0.852,8,-0.2,0.733,-0.2,1.46,-1.46,0.442,0,0,-1.8,0.9
ENSMUSG00000025496,DRD4,dopamine receptor D4,cytoplasm|plasma membrane|integral component of plasma membrane|cell cortex|vesicle membrane|membrane|integral component of membrane|axon|dendrite|neuronal cell body|terminal bouton|dendritic spine|axon terminus|,"activation of MAPK activity|behavioral fear response|synaptic transmission, dopaminergic|response to amphetamine|signal transduction|G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|adenylate cyclase-inhibiting dopamine receptor signaling pathway|adenylate cyclase-inhibiting dopamine receptor signaling pathway|dopamine receptor signaling pathway|short-term memory|associative learning|adult locomotory behavior|olfactory learning|negative regulation of cAMP biosynthetic process|positive regulation of sodium:proton antiporter activity|positive regulation of kinase activity|response to histamine|regulation of dopamine metabolic process|fear response|regulation of circadian rhythm|regulation of neurotransmitter secretion|behavioral response to cocaine|rhythmic process|arachidonic acid secretion|negative regulation of protein secretion|regulation of synaptic transmission|regulation of calcium-mediated signaling|regulation of inhibitory postsynaptic membrane potential|positive regulation of penile erection|negative regulation of voltage-gated calcium channel activity|positive regulation of excitatory postsynaptic membrane potential|","dopamine neurotransmitter receptor activity, coupled via Gi/Go|dopamine neurotransmitter receptor activity, coupled via Gi/Go|signal transducer activity|G-protein coupled receptor activity|dopamine neurotransmitter receptor activity|drug binding|SH3 domain binding|dopamine binding|identical protein binding|",10,0,0,10,0.4,3.62,0.3,1.46,1.46,0.442,0,0,-0.7,1.7
ENSMUSG00000021054,SGPP1,sphingosine-1-phosphate phosphatase 1,endoplasmic reticulum|membrane|integral component of membrane|,sphingolipid metabolic process|sphinganine-1-phosphate metabolic process|sphingosine metabolic process|dephosphorylation|extrinsic apoptotic signaling pathway|intrinsic apoptotic signaling pathway|,"catalytic activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|sphingosine-1-phosphate phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0.2,2.63,10,0,0,0.2,1.46,1.46,0.442,0,0,-1.1,1.5
ENSMUSG00000006154,EPS8L1,EPS8-like 1,ruffle|intracellular|cytoplasm|ruffle membrane|protein complex|extracellular vesicular exosome|,Rho protein signal transduction|Rac protein signal transduction|positive regulation of Rho GTPase activity|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|positive regulation of ruffle assembly|,actin binding|Rho guanyl-nucleotide exchange factor activity|Rac guanyl-nucleotide exchange factor activity|T cell receptor binding|actin filament binding|,10,0.2,0.88,10,-0.5,3.68,-0.4,1.45,-1.45,0.444,0,0,-1.7,0.8
ENSMUSG00000029343,CRYBB1,"crystallin, beta B1",None,None,structural constituent of eye lens|protein binding|,10,-0.3,1.52,10,1.4,0.803,-0.3,1.45,-1.45,0.444,0,0,-1.4,1.9
ENSMUSG00000040963,ASGR2,asialoglycoprotein receptor 2,membrane|integral component of membrane|,endocytosis|glycoprotein metabolic process|regulation of protein stability|lipid homeostasis|,carbohydrate binding|,10,0.4,1.75,10,0.1,0.0869,0.3,1.44,1.44,0.445,0,0,-1.5,1.3
ENSMUSG00000041426,HIBCH,3-hydroxyisobutyryl-Coenzyme A hydrolase,mitochondrion|extracellular vesicular exosome|,branched-chain amino acid catabolic process|,3-hydroxyisobutyryl-CoA hydrolase activity|hydrolase activity|,10,0.4,3.53,10,0,0,0.4,1.44,1.44,0.445,0,0,-0.5,1.9
ENSMUSG00000037493,CIB2,calcium and integrin binding family member 2,photoreceptor inner segment|plasma membrane|muscle tendon junction|membrane|neuromuscular junction|sarcolemma|blood microparticle|,integrin-mediated signaling pathway|photoreceptor cell maintenance|calcium ion homeostasis|,integrin binding|calcium ion binding|protein complex binding|metal ion binding|,10,-0.3,1.96,10,-0.1,0.319,-0.2,1.44,-1.44,0.445,0,0,-1.6,0.8
ENSMUSG00000003345,CSNK1G2,"casein kinase 1, gamma 2",cytoplasm|membrane|,protein phosphorylation|Wnt signaling pathway|phosphorylation|protein autophosphorylation|,"nucleotide binding|magnesium ion binding|glycoprotein binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|peptide binding|phosphoprotein binding|",10,0.5,1.14,10,-0.5,2.82,-0.3,1.43,-1.43,0.447,0,0,-1.7,1
ENSMUSG00000046480,SCN4B,"sodium channel, type IV, beta",voltage-gated sodium channel complex|voltage-gated sodium channel complex|plasma membrane|intercalated disc|membrane|integral component of membrane|intrinsic component of plasma membrane|,transport|ion transport|sodium ion transport|positive regulation of sodium ion transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|cardiac muscle contraction|regulation of ventricular cardiac muscle cell membrane repolarization|cardiac muscle cell action potential involved in contraction|membrane depolarization during cardiac muscle cell action potential|AV node cell to bundle of His cell communication|regulation of heart rate by cardiac conduction|regulation of sodium ion transmembrane transporter activity|,voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|sodium channel activity|sodium channel regulator activity|ion channel binding|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|,10,0.5,0.446,10,0.3,1.39,0.4,1.43,1.43,0.447,0,0,-0.6,1.7
ENSMUSG00000037685,ATP8A1,"ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1",endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|cytoplasmic vesicle|,transport|cation transport|lipid transport|learning|phospholipid transport|positive regulation of cell migration|positive regulation of phospholipid translocation|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|protein binding|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,-0.3,1.68,10,-0.1,0.239,-0.2,1.42,-1.42,0.448,0,0,-1.5,1
ENSMUSG00000040084,BUB1B,"budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)","chromosome, centromeric region|kinetochore|kinetochore|kinetochore|condensed chromosome kinetochore|condensed nuclear chromosome kinetochore|condensed chromosome outer kinetochore|condensed chromosome outer kinetochore|nucleus|chromosome|cytoplasm|perinuclear region of cytoplasm|","protein phosphorylation|apoptotic process|cell cycle|mitotic nuclear division|metaphase/anaphase transition of mitotic cell cycle|phosphorylation|protein localization to kinetochore|cell division|protein localization to chromosome, centromeric region|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",3,-0.1,0.0683,3,-0.5,1.92,-0.5,1.42,-1.42,0.448,0,0,-2,1.2
ENSMUSG00000024867,PIP5K1B,"phosphatidylinositol-4-phosphate 5-kinase, type 1 beta",uropod|membrane|,phosphorylation|phosphatidylinositol metabolic process|phosphatidylinositol phosphorylation|,nucleotide binding|protein binding|ATP binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|transferase activity|,10,0.1,0.213,10,0.3,1.75,0.2,1.42,1.42,0.448,0,0,-1.5,1.2
ENSMUSG00000060550,H2-Q7,"histocompatibility 2, Q region locus 7",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|cell surface|membrane|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,positive regulation of T cell mediated cytotoxicity|immune system process|antigen processing and presentation of peptide antigen via MHC class I|immune response|antigen processing and presentation|,receptor binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,-0.6,2.2,10,0.8,1.53,-0.3,1.41,-1.41,0.45,0,0,-1.4,1.8
ENSMUSG00000038257,GLRA3,"glycine receptor, alpha 3 subunit",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|chloride transmembrane transport|,extracellular ligand-gated ion channel activity|chloride channel activity|glycine binding|extracellular-glycine-gated chloride channel activity|transmitter-gated ion channel activity|,10,0.4,2.28,10,0,0,0.3,1.39,1.39,0.453,0,0,-0.6,1.8
ENSMUSG00000079477,RAB7,"RAB7, member RAS oncogene family",intracellular|cell|cytoplasm|lysosome|lysosome|endosome|late endosome|late endosome|late endosome|Golgi apparatus|membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|phagocytic vesicle|extracellular vesicular exosome|alveolar lamellar body|,GTP catabolic process|protein targeting to lysosome|transport|intracellular protein transport|epidermal growth factor catabolic process|small GTPase mediated signal transduction|endosome to lysosome transport|protein transport|early endosome to late endosome transport|bone resorption|phagosome acidification|phagosome-lysosome fusion|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|Rac GTPase binding|,4,0.5,1.82,1,0,0,0.5,1.39,1.39,0.453,0,0,-1.6,2
ENSMUSG00000039942,PTGER4,prostaglandin E receptor 4 (subtype EP4),intracellular|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|JNK cascade|regulation of ossification|response to lipopolysaccharide|negative regulation of integrin activation|T-helper cell differentiation|negative regulation of cytokine secretion|positive regulation of cytokine secretion|negative regulation of inflammatory response|negative regulation of inflammatory response|negative regulation of inflammatory response|positive regulation of inflammatory response|regulation of stress fiber assembly|bone development|ERK1 and ERK2 cascade|negative regulation of eosinophil extravasation|,signal transducer activity|G-protein coupled receptor activity|prostaglandin receptor activity|prostaglandin E receptor activity|prostaglandin E receptor activity|,10,0.2,0.694,10,0.2,0.813,0.2,1.39,1.39,0.453,0,0,-0.8,1.7
ENSMUSG00000048875,HDHD1A,haloacid dehalogenase-like hydrolase domain containing 1A,extracellular vesicular exosome|,biological_process|metabolic process|nucleotide metabolic process|,molecular_function|hydrolase activity|metal ion binding|,10,0.2,0.713,10,0.2,0.785,0.2,1.38,1.38,0.455,0,0,-0.7,1.7
ENSMUSG00000039725,2810408M09RIK,RIKEN cDNA 2810408M09 gene,nucleus|,protein phosphorylation|,p53 binding|protein serine/threonine kinase activity|,8,-0.4,1.68,8,-0.1,0.024,-0.3,1.38,-1.38,0.455,0,0,-1.9,0.7
ENSMUSG00000020386,SAR1B,SAR1 gene homolog B (S. cerevisiae),intracellular|endoplasmic reticulum|Golgi apparatus|membrane|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,nucleotide binding|GTP binding|metal ion binding|,10,-1.1,0.656,10,0.5,1.82,0.3,1.37,1.37,0.457,0,0,-1.8,1.3
ENSMUSG00000026393,NEK7,NIMA (never in mitosis gene a)-related expressed kinase 7,nucleus|cytoplasm|cytoskeleton|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.4,1.21,10,0.9,1.81,0.6,1.37,1.37,0.457,0,0,-0.3,2
ENSMUSG00000036887,C1QA,"complement component 1, q subcomponent, alpha polypeptide",extracellular region|collagen trimer|extracellular vesicular exosome|,"immune system process|complement activation, classical pathway|innate immune response|",protein binding|,10,-0.3,1.89,10,-0.1,0.0671,-0.2,1.34,-1.34,0.462,0,0,-1.6,0.9
ENSMUSG00000067229,CYP2C66,"cytochrome P450, family 2, subfamily c, polypeptide 66",intracellular membrane-bounded organelle|,hematopoietic progenitor cell differentiation|oxidation-reduction process|,monooxygenase activity|drug binding|testosterone 16-alpha-hydroxylase activity|steroid hydroxylase activity|oxidoreductase activity|caffeine oxidase activity|metal ion binding|,10,-0.6,1.18,10,-0.2,0.726,-0.2,1.34,-1.34,0.462,0,0,-1.9,0.6
ENSMUSG00000031834,PIK3R2,"phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)",intracellular|phosphatidylinositol 3-kinase complex|,signal transduction|insulin receptor signaling pathway|regulation of phosphorylation|,protein binding|1-phosphatidylinositol-3-kinase activity|receptor tyrosine kinase binding|phosphatidylinositol 3-kinase regulator activity|,10,0.3,1.89,10,0.8,1.63,0.3,1.34,1.34,0.462,0,0,-0.6,2
ENSMUSG00000029136,RBKS,ribokinase,extracellular vesicular exosome|,carbohydrate metabolic process|D-ribose metabolic process|phosphorylation|,"nucleotide binding|ribokinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|",10,0.1,0.298,10,0.8,2.59,0.5,1.33,1.33,0.464,0,0,-0.3,2
ENSMUSG00000043572,PARS2,prolyl-tRNA synthetase (mitochondrial)(putative),cytoplasm|mitochondrion|,translation|tRNA aminoacylation for protein translation|prolyl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA ligase activity|proline-tRNA ligase activity|ATP binding|ligase activity|,8,-0.2,1.04,8,-0.6,0.811,-0.3,1.33,-1.33,0.464,0,0,-1.8,1.1
ENSMUSG00000028959,FASTK,Fas-activated serine/threonine kinase,mitochondrion|nuclear speck|,protein phosphorylation|apoptotic process|phosphorylation|regulation of RNA splicing|,nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|Fas-activated serine/threonine kinase activity|,10,0.6,1.3,10,0.2,0.529,0.3,1.33,1.33,0.464,0,0,-0.8,1.7
ENSMUSG00000032294,PKM,"pyruvate kinase, muscle",nucleus|cytoplasm|mitochondrion|mitochondrion|plasma membrane|cilium|extracellular vesicular exosome|,liver development|glucose metabolic process|glycolytic process|glycolytic process|ATP biosynthetic process|metabolic process|programmed cell death|phosphorylation|organ regeneration|pyruvate biosynthetic process|skeletal muscle tissue regeneration|,nucleotide binding|magnesium ion binding|catalytic activity|pyruvate kinase activity|pyruvate kinase activity|protein binding|ATP binding|kinase activity|transferase activity|MHC class II protein complex binding|potassium ion binding|ADP binding|poly(A) RNA binding|metal ion binding|,7,-0.6,3.47,7,0,0,-0.4,1.31,-1.31,0.467,0,0,-2,0.5
ENSMUSG00000041119,PDE9A,phosphodiesterase 9A,cytosol|perikaryon|,signal transduction|metabolic process|,"3',5'-cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|3',5'-cyclic-GMP phosphodiesterase activity|3',5'-cyclic-GMP phosphodiesterase activity|",10,-0.3,1.86,10,0.1,0.268,-0.2,1.3,-1.3,0.469,0,0,-1.7,0.8
ENSMUSG00000001670,TAT,tyrosine aminotransferase,mitochondrion|mitochondrion|,2-oxoglutarate metabolic process|2-oxoglutarate metabolic process|cellular amino acid metabolic process|glutamate metabolic process|glutamate metabolic process|L-phenylalanine catabolic process|tyrosine catabolic process|tyrosine catabolic process|response to oxidative stress|biosynthetic process|aromatic amino acid family metabolic process|aromatic amino acid family catabolic process|response to organic cyclic compound|response to mercury ion|response to glucocorticoid|,catalytic activity|L-tyrosine:2-oxoglutarate aminotransferase activity|L-tyrosine:2-oxoglutarate aminotransferase activity|transaminase activity|amino acid binding|transferase activity|pyridoxal phosphate binding|L-phenylalanine:2-oxoglutarate aminotransferase activity|,10,0.2,1.07,10,-0.6,3,0.2,1.29,1.29,0.471,0,0,-1.7,0.9
ENSMUSG00000022843,CLCN2,chloride channel 2,membrane|integral component of membrane|dendrite|chloride channel complex|perikaryon|,transport|ion transport|chloride transport|regulation of ion transmembrane transport|regulation of anion transport|transmembrane transport|retina development in camera-type eye|cell differentiation involved in salivary gland development|chloride transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated chloride channel activity|voltage-gated chloride channel activity|chloride channel activity|adenyl nucleotide binding|,10,1.3,2.35,10,-0.4,1.31,-0.3,1.29,-1.29,0.471,0,0,-1,2
ENSMUSG00000030774,PAK1,p21 protein (Cdc42/Rac)-activated kinase 1,ruffle|intracellular|nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|cell-cell junction|focal adhesion|intercalated disc|membrane|Z disc|cell junction|axon|axon|dendrite|growth cone|nuclear membrane|cell projection|protein complex|,response to hypoxia|positive regulation of protein phosphorylation|protein phosphorylation|protein phosphorylation|exocytosis|apoptotic process|neuromuscular junction development|metabolic process|response to organic substance|phosphorylation|dendrite development|signal transduction by phosphorylation|actin cytoskeleton reorganization|cellular response to insulin stimulus|regulation of actin cytoskeleton organization|positive regulation of peptidyl-serine phosphorylation|positive regulation of intracellular estrogen receptor signaling pathway|wound healing|receptor clustering|positive regulation of JUN kinase activity|protein autophosphorylation|branching morphogenesis of an epithelial tube|neuron projection morphogenesis|positive regulation of stress fiber assembly|negative regulation of cell proliferation involved in contact inhibition|,"nucleotide binding|catalytic activity|protein kinase activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|collagen binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|",10,0.1,0.384,10,-1.2,4.51,-1.2,1.28,-1.28,0.472,0,0,-2,0.5
ENSMUSG00000003809,GCDH,glutaryl-Coenzyme A dehydrogenase,mitochondrion|mitochondrion|mitochondrial inner membrane|,acyl-CoA metabolic process|metabolic process|fatty acid oxidation|fatty-acyl-CoA biosynthetic process|oxidation-reduction process|,"fatty-acyl-CoA binding|acyl-CoA dehydrogenase activity|glutaryl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|flavin adenine dinucleotide binding|",10,0.2,0.275,10,-0.7,3.03,-0.4,1.28,-1.28,0.472,0,0,-1.7,1.6
ENSMUSG00000003849,NQO1,"NAD(P)H dehydrogenase, quinone 1",cytoplasm|cytosol|neuronal cell body|extracellular vesicular exosome|,superoxide metabolic process|response to oxidative stress|removal of superoxide radicals|negative regulation of catalytic activity|positive regulation of neuron apoptotic process|oxidation-reduction process|,NAD(P)H dehydrogenase (quinone) activity|NAD(P)H dehydrogenase (quinone) activity|superoxide dismutase activity|oxidoreductase activity|poly(A) RNA binding|,10,-0.1,0.0375,10,0.3,1.54,0.2,1.27,1.27,0.474,0,0,-1.5,1.2
ENSMUSG00000018906,P4HA2,"procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide",collagen trimer|nucleus|cytoplasm|endoplasmic reticulum|procollagen-proline 4-dioxygenase complex|intracellular membrane-bounded organelle|,peptidyl-proline hydroxylation to 4-hydroxy-L-proline|oxidation-reduction process|,"procollagen-proline 4-dioxygenase activity|iron ion binding|protein binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|L-ascorbic acid binding|metal ion binding|dioxygenase activity|",10,0.5,3.43,10,-0.2,1.23,0.5,1.27,1.27,0.474,0,0,-0.8,1.7
ENSMUSG00000049404,RARRES1,retinoic acid receptor responder (tazarotene induced) 1,extracellular vesicular exosome|,biological_process|,molecular_function|,10,1,2.81,10,0,0,0.5,1.25,1.25,0.478,0,0,-0.3,2
ENSMUSG00000019464,PTGER1,prostaglandin E receptor 1 (subtype EP1),plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|response to lipopolysaccharide|,signal transducer activity|G-protein coupled receptor activity|prostaglandin receptor activity|prostaglandin E receptor activity|,10,0.2,0.426,10,0.4,1.17,0.2,1.25,1.25,0.478,0,0,-1,1.7
ENSMUSG00000059077,PTH,parathyroid hormone,extracellular space|extracellular space|intracellular|,negative regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cellular calcium ion homeostasis|cellular calcium ion homeostasis|adenylate cyclase-activating G-protein coupled receptor signaling pathway|Rho protein signal transduction|cell-cell signaling|positive regulation of signal transduction|regulation of gene expression|regulation of gene expression|positive regulation of bone mineralization|positive regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|cellular macromolecule biosynthetic process|positive regulation of glycogen biosynthetic process|positive regulation of ossification|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of glucose import|,RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|hormone activity|parathyroid hormone receptor binding|type 1 parathyroid hormone receptor binding|peptide hormone receptor binding|,10,0.2,0.897,10,0.3,0.51,0.2,1.25,1.25,0.478,0,0,-1.3,1.5
ENSMUSG00000037601,NME1,NME/NM23 nucleoside diphosphate kinase 1,nucleus|cytoplasm|mitochondrion|centrosome|cytosol|intermediate filament|membrane|ruffle membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,negative regulation of myeloid leukocyte differentiation|nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|DNA catabolic process|endocytosis|nervous system development|lactation|nucleotide metabolic process|negative regulation of gene expression|positive regulation of neuron projection development|phosphorylation|cell differentiation|mammary gland development|positive regulation of DNA binding|positive regulation of epithelial cell proliferation|nucleic acid phosphodiester bond hydrolysis|,nucleotide binding|magnesium ion binding|RNA polymerase II regulatory region sequence-specific DNA binding|single-stranded DNA binding|deoxyribonuclease activity|nucleoside diphosphate kinase activity|ATP binding|GTP binding|kinase activity|transferase activity|intermediate filament binding|enzyme binding|protein kinase binding|identical protein binding|gamma-tubulin binding|ribosomal small subunit binding|poly(A) RNA binding|metal ion binding|,10,0.3,1,10,-1.1,2.01,0.3,1.25,1.25,0.478,0,0,-2,0.9
ENSMUSG00000037610,KCNMB2,"potassium large conductance calcium-activated channel, subfamily M, beta member 2",integral component of plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,action potential|detection of calcium ion|transport|ion transport|potassium ion transport|neuronal action potential|potassium ion transmembrane transport|,potassium channel activity|calcium-activated potassium channel activity|,10,-0.2,0.222,10,-0.2,1.1,-0.2,1.23,-1.23,0.482,0,0,-1.7,0.8
ENSMUSG00000030871,EARS2,glutamyl-tRNA synthetase 2 (mitochondrial)(putative),cytoplasm|mitochondrion|mitochondrion|,translation|tRNA aminoacylation for protein translation|glutamyl-tRNA aminoacylation|tRNA aminoacylation|tRNA aminoacylation for mitochondrial protein translation|,"tRNA binding|nucleotide binding|RNA binding|aminoacyl-tRNA ligase activity|glutamate-tRNA ligase activity|ATP binding|ligase activity|ligase activity, forming aminoacyl-tRNA and related compounds|glutamate-tRNA(Gln) ligase activity|",5,0.3,1.52,5,0.1,0.171,0.3,1.23,1.23,0.482,0,0,-1.3,1.9
ENSMUSG00000040653,PPP1R14C,"protein phosphatase 1, regulatory (inhibitor) subunit 14c",cytoplasm|membrane|,signal transduction|regulation of phosphorylation|negative regulation of catalytic activity|negative regulation of catalytic activity|,protein phosphatase inhibitor activity|protein serine/threonine phosphatase inhibitor activity|protein serine/threonine phosphatase inhibitor activity|,10,-0.6,1.36,10,-1.2,1.42,-1.1,1.21,-1.21,0.485,0,0,-2,0.3
ENSMUSG00000029446,PSPH,phosphoserine phosphatase,cytoplasm|neuron projection|,L-serine metabolic process|L-serine biosynthetic process|metabolic process|cellular amino acid biosynthetic process|dephosphorylation|dephosphorylation|,magnesium ion binding|magnesium ion binding|phosphoserine phosphatase activity|phosphoserine phosphatase activity|calcium ion binding|hydrolase activity|phosphatase activity|protein homodimerization activity|metal ion binding|,10,0.8,4.1,10,-0.2,0.0529,0.8,1.21,1.21,0.485,0,0,-0.5,1.9
ENSMUSG00000022562,OPLAH,5-oxoprolinase (ATP-hydrolysing),cellular_component|,glutathione metabolic process|,nucleotide binding|catalytic activity|ATP binding|hydrolase activity|5-oxoprolinase (ATP-hydrolyzing) activity|,10,-0.1,0.167,10,-0.3,1.49,-0.2,1.2,-1.2,0.487,0,0,-1.7,0.8
ENSMUSG00000057880,ABAT,4-aminobutyrate aminotransferase,mitochondrion|mitochondrion|4-aminobutyrate transaminase complex|neuron projection|extracellular vesicular exosome|,response to hypoxia|copulation|locomotory behavior|gamma-aminobutyric acid metabolic process|response to iron ion|response to nicotine|neurotransmitter catabolic process|response to cocaine|response to drug|response to ethanol|negative regulation of blood pressure|behavioral response to cocaine|,catalytic activity|4-aminobutyrate transaminase activity|4-aminobutyrate transaminase activity|transaminase activity|transferase activity|pyridoxal phosphate binding|protein homodimerization activity|(S)-3-amino-2-methylpropionate transaminase activity|,10,0.3,0.576,10,0.2,0.881,0.2,1.2,1.2,0.487,0,0,-0.9,1.7
ENSMUSG00000025428,ATP5A1,"ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1","mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|plasma membrane|COP9 signalosome|membrane|membrane|proton-transporting two-sector ATPase complex, catalytic domain|proton-transporting ATP synthase complex, catalytic core F(1)|extracellular vesicular exosome|",negative regulation of endothelial cell proliferation|ADP biosynthetic process|ATP catabolic process|ATP catabolic process|lipid metabolic process|ATP biosynthetic process|transport|ion transport|embryo development|ATP synthesis coupled proton transport|ATP hydrolysis coupled proton transport|proton transport|ATP metabolic process|hydrogen ion transmembrane transport|,"nucleotide binding|ATP binding|ATP binding|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|ATPase activity|ATPase activity|MHC class I protein binding|ADP binding|poly(A) RNA binding|proton-transporting ATP synthase activity, rotational mechanism|proton-transporting ATPase activity, rotational mechanism|",7,-0.5,1.33,7,0.3,0.655,0.3,1.2,1.2,0.487,0,0,-1.8,1.3
ENSMUSG00000038970,LMTK2,lemur tyrosine kinase 2,cytoplasm|early endosome|Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|recycling endosome|,receptor recycling|protein phosphorylation|nervous system development|axon guidance|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|endocytic recycling|transferrin transport|negative regulation of catalytic activity|early endosome to late endosome transport|protein autophosphorylation|protein autophosphorylation|neurotrophin TRK receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein phosphatase inhibitor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|myosin VI binding|",10,0,0,10,-1.3,4.22,-1.3,1.19,-1.19,0.489,0,0,-2,0.4
ENSMUSG00000024769,CDC42BPG,CDC42 binding protein kinase gamma (DMPK-like),cytoplasm|cell leading edge|,protein phosphorylation|phosphorylation|intracellular signal transduction|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.1,0.0767,10,0.5,1.85,0.3,1.18,1.18,0.491,0,0,-0.5,1.9
ENSMUSG00000090175,UGT1A9,"UDP glucuronosyltransferase 1 family, polypeptide A9",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,metabolic process|negative regulation of catalytic activity|,"enzyme inhibitor activity|protein kinase C binding|steroid binding|fatty acid binding|drug binding|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|enzyme binding|protein homodimerization activity|protein heterodimerization activity|",5,-0.3,0.71,5,0.3,1.13,0.3,1.18,1.18,0.491,0,0,-1.2,2
ENSMUSG00000020123,AVPR1A,arginine vasopressin receptor 1A,plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,regulation of systemic arterial blood pressure by vasopressin|maternal aggressive behavior|positive regulation of systemic arterial blood pressure|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|negative regulation of female receptivity|grooming behavior|positive regulation of cell proliferation|response to organic substance|response to inorganic substance|positive regulation of heart rate|positive regulation of glutamate secretion|calcium-mediated signaling|positive regulation of cell growth|positive regulation of prostaglandin biosynthetic process|positive regulation of cellular pH reduction|social behavior|positive regulation of renal sodium excretion|maternal behavior|sperm ejaculation|penile erection|positive regulation of blood pressure|positive regulation of vasoconstriction|negative regulation of transmission of nerve impulse|,signal transducer activity|G-protein coupled receptor activity|vasopressin receptor activity|peptide hormone binding|V1A vasopressin receptor binding|,10,0,0,10,0.6,2.12,0.4,1.18,1.18,0.491,0,0,-0.6,1.9
ENSMUSG00000036504,PHPT1,phosphohistidine phosphatase 1,cytoplasm|cytosol|cytosol|extracellular vesicular exosome|,protein dephosphorylation|positive regulation of insulin secretion involved in cellular response to glucose stimulus|peptidyl-histidine dephosphorylation|negative regulation of T cell receptor signaling pathway|negative regulation of lyase activity|positive regulation of cell motility|positive regulation of cell motility|regulation of actin cytoskeleton reorganization|negative regulation of ATP citrate synthase activity|,"phosphoprotein phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|calcium channel inhibitor activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|ion channel binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0,0,10,0.5,2.61,0.4,1.17,1.17,0.493,0,0,-0.8,1.9
ENSMUSG00000020151,PTPRR,"protein tyrosine phosphatase, receptor type, R",extracellular space|cytoplasm|plasma membrane|membrane|integral component of membrane|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|protein kinase binding|,10,0.8,4.2,10,-0.2,0.575,0.8,1.17,1.17,0.493,0,0,-0.8,2
ENSMUSG00000052920,PRKG1,"protein kinase, cGMP-dependent, type I",acrosomal vesicle|intracellular|nucleoplasm|cytoplasm|Golgi apparatus|Golgi apparatus|cytosol|plasma membrane|plasma membrane|plasma membrane|membrane|,neuron migration|protein phosphorylation|protein phosphorylation|signal transduction|positive regulation of cytosolic calcium ion concentration|metabolic process|negative regulation of inositol phosphate biosynthetic process|negative regulation of glutamate secretion|negative regulation of smooth muscle cell migration|phosphorylation|dendrite development|cGMP-mediated signaling|forebrain development|positive regulation of circadian rhythm|regulation of GTPase activity|negative regulation of heart contraction|positive regulation of vasodilation|negative regulation of smooth muscle contraction|relaxation of vascular smooth muscle|cell growth involved in cardiac muscle cell development|negative regulation of platelet aggregation|positive regulation of large conductance calcium-activated potassium channel activity|regulation of testosterone biosynthetic process|,"nucleotide binding|catalytic activity|protein kinase activity|protein serine/threonine kinase activity|cGMP-dependent protein kinase activity|cGMP-dependent protein kinase activity|calcium channel regulator activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cGMP binding|protein homodimerization activity|mitogen-activated protein kinase p38 binding|",10,-0.1,0.082,10,0.8,2.7,0.7,1.17,1.17,0.493,0,0,-0.6,2
ENSMUSG00000029410,PPEF2,"protein phosphatase, EF hand calcium-binding domain 2",None,visual perception|negative regulation of peptidyl-threonine phosphorylation|dephosphorylation|negative regulation of MAPK cascade|response to stimulus|detection of stimulus involved in sensory perception|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|iron ion binding|calcium ion binding|hydrolase activity|manganese ion binding|Hsp70 protein binding|mitogen-activated protein kinase kinase kinase binding|metal ion binding|Hsp90 protein binding|,10,-0.1,0.0106,10,-0.3,1.27,-0.2,1.15,-1.15,0.497,0,0,-1.7,0.8
ENSMUSG00000024777,PPP2R5B,"protein phosphatase 2, regulatory subunit B', beta",None,regulation of protein phosphorylation|regulation of receptor activity|positive regulation of neuron projection development|positive regulation of protein complex assembly|regulation of protein autophosphorylation|positive regulation of transcription from RNA polymerase II promoter|regulation of peptidyl-tyrosine phosphorylation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of neurotrophin TRK receptor signaling pathway|negative regulation of G0 to G1 transition|positive regulation of cell cycle arrest|cellular response to growth factor stimulus|,None,10,-0.2,0.557,10,-0.2,0.695,-0.2,1.15,-1.15,0.497,0,0,-1.7,0.8
ENSMUSG00000026027,STRADB,STE20-related kinase adaptor beta,intracellular|nucleus|cytoplasm|,cell morphogenesis|protein phosphorylation|protein export from nucleus|cytoskeleton organization|cell cycle|JNK cascade|activation of protein kinase activity|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|ATP binding|transferase activity, transferring phosphorus-containing groups|",10,-0.2,1.12,10,0.5,1,-0.2,1.14,-1.14,0.499,0,0,-1.1,1.7
ENSMUSG00000031012,CASK,calcium/calmodulin-dependent serine protein kinase (MAGUK family),basement membrane|basement membrane|nucleus|nucleus|nuclear lamina|nucleolus|cytoplasm|cytoplasm|cytosol|plasma membrane|cell-cell junction|cell-cell junction|membrane|membrane|basolateral plasma membrane|nuclear matrix|dendrite|presynaptic membrane|protein complex|synapse|ciliary membrane|synaptic membrane|,negative regulation of cell-matrix adhesion|protein phosphorylation|intracellular protein transport|negative regulation of keratinocyte proliferation|phosphorylation|positive regulation of transcription from RNA polymerase II promoter|negative regulation of wound healing|calcium ion import|positive regulation of calcium ion import|negative regulation of cellular response to growth factor stimulus|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|calmodulin binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|PDZ domain binding|protein complex binding|neurexin family protein binding|neurexin family protein binding|",10,-0.4,2.76,10,0,0,-0.2,1.14,-1.14,0.499,0,0,-1.7,0.9
ENSMUSG00000032262,ELOVL4,"elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4",endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,"lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation, saturated fatty acid|very long-chain fatty acid biosynthetic process|",transferase activity|,10,0.1,0.0674,10,0.4,1.73,0.2,1.14,1.14,0.499,0,0,-0.8,1.8
ENSMUSG00000015806,QDPR,quinoid dihydropteridine reductase,cytoplasm|mitochondrion|cytosol|neuron projection|extracellular vesicular exosome|,tetrahydrobiopterin biosynthetic process|metabolic process|oxidation-reduction process|,"6,7-dihydropteridine reductase activity|oxidoreductase activity|protein homodimerization activity|NADPH binding|NADH binding|",10,0.7,2.79,10,0.1,0.112,0.3,1.13,1.13,0.501,0,0,-0.6,1.9
ENSMUSG00000056379,TAAR1,trace amine-associated receptor 1,plasma membrane|membrane|integral component of membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|,trace-amine receptor activity|trace-amine receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|,10,0.2,1.07,10,0.2,0.117,0.2,1.1,1.1,0.506,0,0,-0.4,1.9
ENSMUSG00000042978,SBK1,SH3-binding kinase 1,cellular_component|cytoplasm|,protein phosphorylation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.3,1.46,10,0.1,0.0232,-0.3,1.07,-1.07,0.512,0,0,-1.5,1.1
ENSMUSG00000020098,PCBD1,pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1,nucleus|nucleus|cytoplasm|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|tetrahydrobiopterin biosynthetic process|regulation of protein homodimerization activity|positive regulation of transcription, DNA-templated|protein homotetramerization|protein heterooligomerization|oxidation-reduction process|",transcription coactivator activity|phenylalanine 4-monooxygenase activity|protein binding|4-alpha-hydroxytetrahydrobiopterin dehydratase activity|lyase activity|identical protein binding|,10,0.3,0.64,10,0.5,0.812,0.4,1.06,1.06,0.513,0,0,-0.4,1.9
ENSMUSG00000022836,MYLK,"myosin, light polypeptide kinase",stress fiber|cytoplasm|cytoskeleton|cell-cell junction|lamellipodium|cleavage furrow|cell projection|extracellular vesicular exosome|,protein phosphorylation|smooth muscle contraction|actin filament organization|tonic smooth muscle contraction|phosphorylation|positive regulation of cell migration|positive regulation of cell migration|bleb assembly|positive regulation of calcium ion transport|aorta smooth muscle tissue morphogenesis|cellular hypotonic response|positive regulation of wound healing|,"nucleotide binding|actin binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|myosin light chain kinase activity|myosin light chain kinase activity|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|metal ion binding|",10,0,0,10,-1,3.78,-1,1.06,-1.06,0.513,0,0,-2,0.2
ENSMUSG00000031492,CHRNB3,"cholinergic receptor, nicotinic, beta polypeptide 3",plasma membrane|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|neuron projection|synapse|postsynaptic membrane|,transport|ion transport|protein heterooligomerization|,acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|drug binding|acetylcholine binding|,10,-0.2,0.502,10,-0.4,1.01,-0.3,1.05,-1.05,0.516,0,0,-1.7,0.9
ENSMUSG00000039130,ZC3HC1,"zinc finger, C3HC type 1",nucleus|nucleus|nuclear membrane|,cell cycle|mitotic nuclear division|cell division|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,protein binding|zinc ion binding|protein kinase binding|metal ion binding|,10,-0.3,0.788,10,-0.2,0.438,-0.2,1.04,-1.04,0.517,0,0,-1.7,0.8
ENSMUSG00000023045,SOAT2,sterol O-acyltransferase 2,endoplasmic reticulum|endoplasmic reticulum membrane|brush border|membrane|integral component of membrane|,lipid metabolic process|steroid metabolic process|cholesterol metabolic process|cholesterol metabolic process|cholesterol efflux|very-low-density lipoprotein particle assembly|cholesterol esterification|,"fatty-acyl-CoA binding|sterol O-acyltransferase activity|sterol O-acyltransferase activity|O-acyltransferase activity|cholesterol binding|transferase activity|transferase activity, transferring acyl groups|cholesterol O-acyltransferase activity|",10,-0.4,3.04,10,0.1,0.0104,-0.3,1.02,-1.02,0.521,0,0,-1.6,1
ENSMUSG00000028298,CGA,"glycoprotein hormones, alpha subunit",extracellular region|cell|,thyroid hormone generation|gonad development|thyroid gland development|luteinizing hormone secretion|cellular response to hormone stimulus|negative regulation of organ growth|follicle-stimulating hormone secretion|developmental growth|,hormone activity|,10,0.1,0.166,10,-0.2,1.69,-0.2,1.02,-1.02,0.521,0,0,-1.5,1.1
ENSMUSG00000020377,LTC4S,leukotriene C4 synthase,nucleus|nuclear envelope|nuclear envelope|endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,leukotriene metabolic process|leukotriene metabolic process|leukotriene biosynthetic process|leukotriene biosynthetic process|oxidation-reduction process|,glutathione transferase activity|leukotriene-C4 synthase activity|leukotriene-C4 synthase activity|glutathione peroxidase activity|enzyme activator activity|lipid binding|lipid binding|lyase activity|glutathione binding|protein heterodimerization activity|,10,0.1,0.267,10,0.2,1.08,0.1,1.02,1.02,0.521,0,0,-1,1.6
ENSMUSG00000024843,CHKA,choline kinase alpha,cytoplasm|,lipid metabolic process|phosphatidylethanolamine biosynthetic process|phosphatidylcholine biosynthetic process|phosphatidylcholine biosynthetic process|CDP-choline pathway|CDP-choline pathway|phospholipid biosynthetic process|phosphorylation|choline metabolic process|,"nucleotide binding|choline kinase activity|choline kinase activity|cholinesterase activity|ethanolamine kinase activity|ATP binding|drug binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|choline binding|protein homodimerization activity|",10,0.1,0.847,9,0.1,0.265,0.1,1.02,1.02,0.521,0,0,-1.3,1.5
ENSMUSG00000000215,INS2,insulin II,extracellular region|extracellular space|intracellular|nucleus|small nucleolar ribonucleoprotein complex|cytoplasm|secretory granule|secretory granule|secretory granule|,negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|activation of MAPK activity|negative regulation of acute inflammatory response|carbohydrate metabolic process|glucose metabolic process|regulation of cellular amino acid metabolic process|acute-phase response|ER overload response|G-protein coupled receptor signaling pathway|myoblast fusion|positive regulation of cell proliferation|insulin receptor signaling pathway|regulation of gene expression|positive regulation of phosphatidylinositol 3-kinase signaling|myotube differentiation|glucose transport|glucose transport|lipid catabolic process|regulation of transmembrane transporter activity|activation of protein kinase B activity|positive regulation of cellular protein metabolic process|negative regulation of protein oligomerization|regulation of protein localization|negative regulation of NAD(P)H oxidase activity|wound healing|negative regulation of protein catabolic process|regulation of phosphorylation|glucose homeostasis|regulation of protein binding|positive regulation of MAPK cascade|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of glycogen biosynthetic process|positive regulation of DNA replication|negative regulation of glycogen catabolic process|positive regulation of glycolytic process|positive regulation of mitosis|negative regulation of proteolysis|negative regulation of fatty acid metabolic process|positive regulation of glucose import|positive regulation of insulin receptor signaling pathway|alpha-beta T cell activation|regulation of protein secretion|negative regulation of protein secretion|positive regulation of cytokine secretion|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of NF-kappaB transcription factor activity|positive regulation of protein kinase B signaling|fatty acid homeostasis|canonical Wnt signaling pathway|negative regulation of respiratory burst involved in inflammatory response|positive regulation of respiratory burst|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of feeding behavior|,protease binding|insulin receptor binding|insulin-like growth factor receptor binding|hormone activity|protein complex binding|identical protein binding|,10,1.1,3.04,10,-0.2,0.543,0.2,1.02,1.02,0.521,0,0,-0.6,2
ENSMUSG00000030826,BCAT2,"branched chain aminotransferase 2, mitochondrial",nucleus|cytoplasm|mitochondrion|mitochondrion|,isoleucine metabolic process|isoleucine catabolic process|isoleucine catabolic process|leucine metabolic process|valine metabolic process|metabolic process|cellular amino acid biosynthetic process|branched-chain amino acid metabolic process|branched-chain amino acid biosynthetic process|branched-chain amino acid catabolic process|branched-chain amino acid catabolic process|leucine biosynthetic process|regulation of hormone levels|,catalytic activity|branched-chain-amino-acid transaminase activity|branched-chain-amino-acid transaminase activity|transaminase activity|transferase activity|L-leucine transaminase activity|L-valine transaminase activity|L-isoleucine transaminase activity|,10,-0.1,0.0994,10,0.2,1.42,0.2,0.993,0.993,0.526,0,0,-1,1.6
ENSMUSG00000026807,AK8,adenylate kinase 8,cellular_component|cytoplasm|,nucleobase-containing compound metabolic process|nucleoside diphosphate phosphorylation|nucleoside triphosphate biosynthetic process|phosphorylation|ventricular system development|,nucleotide binding|adenylate kinase activity|cytidylate kinase activity|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|nucleobase-containing compound kinase activity|,10,-0.3,1.02,10,0.4,1.45,-0.3,0.986,-0.986,0.528,0,0,-1.3,1.5
ENSMUSG00000079037,PRNP,prion protein,cytoplasm|mitochondrial outer membrane|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|membrane|membrane|anchored component of membrane|membrane raft|membrane raft|extracellular vesicular exosome|,negative regulation of protein phosphorylation|nucleobase-containing compound metabolic process|cellular copper ion homeostasis|response to oxidative stress|learning or memory|negative regulation of interferon-gamma production|negative regulation of interleukin-17 production|negative regulation of interleukin-2 production|regulation of protein localization|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of activated T cell proliferation|response to cadmium ion|response to copper ion|negative regulation of T cell receptor signaling pathway|protein homooligomerization|negative regulation of calcineurin-NFAT signaling cascade|regulation of potassium ion transmembrane transport|,copper ion binding|copper ion binding|protein binding|microtubule binding|tubulin binding|identical protein binding|identical protein binding|ATP-dependent protein binding|metal ion binding|chaperone binding|,10,-0.3,0.944,10,-0.1,0.281,-0.2,0.983,-0.983,0.528,0,0,-1.8,0.7
ENSMUSG00000005534,INSR,insulin receptor,nucleus|endosome|cytosol|plasma membrane|plasma membrane|integral component of plasma membrane|insulin receptor complex|caveola|caveola|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|receptor complex|synapse|extracellular vesicular exosome|,"activation of MAPK activity|negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|heart morphogenesis|regulation of transcription, DNA-templated|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cell proliferation|insulin receptor signaling pathway|insulin receptor signaling pathway|epidermis development|organ morphogenesis|regulation of hydrogen peroxide metabolic process|positive regulation of glycoprotein biosynthetic process|negative regulation of gene expression|phosphorylation|peptidyl-tyrosine phosphorylation|transformation of host cell by virus|signal transduction by phosphorylation|male sex determination|positive regulation of cell migration|exocrine pancreas development|activation of protein kinase activity|activation of protein kinase B activity|negative regulation of transporter activity|cellular response to insulin stimulus|response to tumor necrosis factor|intracellular signal transduction|peptidyl-tyrosine autophosphorylation|positive regulation of phosphorylation|glucose homeostasis|positive regulation of MAPK cascade|positive regulation of nitric oxide biosynthetic process|positive regulation of glycogen biosynthetic process|positive regulation of glycogen biosynthetic process|positive regulation of DNA replication|positive regulation of glycolytic process|positive regulation of mitosis|positive regulation of mitosis|regulation of embryonic development|positive regulation of glucose import|protein autophosphorylation|positive regulation of developmental growth|protein heterotetramerization|positive regulation of protein kinase B signaling|positive regulation of respiratory burst|cellular response to growth factor stimulus|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity|insulin-activated receptor activity|insulin-like growth factor receptor binding|protein binding|ATP binding|GTP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein phosphatase binding|protein domain specific binding|lipoic acid binding|insulin-like growth factor I binding|insulin-like growth factor II binding|protein complex binding|3-phosphoinositide-dependent protein kinase binding|phosphatidylinositol 3-kinase binding|insulin binding|insulin receptor substrate binding|PTB domain binding|",10,0.2,0.0622,10,-0.4,1.61,-0.2,0.981,-0.981,0.529,0,0,-1,2
ENSMUSG00000061393,ACVR2B,activin receptor IIB,cell|cytoplasm|plasma membrane|membrane|integral component of membrane|protein complex|,"skeletal system development|skeletal system development|gastrulation with mouth forming second|kidney development|kidney development|lymphangiogenesis|blood vessel remodeling|regulation of transcription, DNA-templated|protein phosphorylation|signal transduction|transmembrane receptor protein serine/threonine kinase signaling pathway|determination of left/right symmetry|determination of left/right symmetry|pattern specification process|mesoderm development|heart development|heart development|response to glucose|post-embryonic development|post-embryonic development|anterior/posterior pattern specification|anterior/posterior pattern specification|anterior/posterior pattern specification|regulation of signal transduction|phosphorylation|insulin secretion|lung development|positive regulation of bone mineralization|BMP signaling pathway|pancreas development|activation of protein kinase activity|positive regulation of activin receptor signaling pathway|organ growth|odontogenesis of dentin-containing tooth|odontogenesis of dentin-containing tooth|positive regulation of osteoblast differentiation|embryonic foregut morphogenesis|skeletal system morphogenesis|skeletal system morphogenesis|palate development|palate development|lymphatic endothelial cell differentiation|artery development|venous blood vessel development|retina vasculature development in camera-type eye|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|transforming growth factor beta-activated receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|growth factor binding|growth factor binding|inhibin binding|metal ion binding|activin binding|activin binding|activin binding|",10,0,0,10,-0.6,1.61,-0.3,0.975,-0.975,0.53,0,0,-1.9,0.5
ENSMUSG00000031584,GSR,glutathione reductase,cytoplasm|mitochondrion|mitochondrion|cytosol|external side of plasma membrane|extracellular vesicular exosome|,glutathione metabolic process|glutathione metabolic process|spermatogenesis|cell redox homeostasis|oxidation-reduction process|,"glutathione-disulfide reductase activity|glutathione-disulfide reductase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor|protein homodimerization activity|glutathione binding|flavin adenine dinucleotide binding|NADP binding|",10,0.5,1.42,10,-0.4,1.59,-0.4,0.971,-0.971,0.531,0,0,-1.4,1.3
ENSMUSG00000028756,PINK1,PTEN induced putative kinase 1,chromatin|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial intermembrane space|cytosol|cytoskeleton|membrane|membrane|integral component of membrane|,"mitochondrion degradation|protein phosphorylation|protein phosphorylation|autophagy|response to stress|phosphorylation|protein ubiquitination|peptidyl-serine phosphorylation|regulation of protein ubiquitination|positive regulation of synaptic transmission, dopaminergic|positive regulation of dopamine secretion|positive regulation of catecholamine secretion|intracellular signal transduction|intracellular signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|regulation of protein complex assembly|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of release of cytochrome c from mitochondria|cellular response to toxic substance|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|","nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|ATP binding|calcium-dependent protein kinase activity|kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|ubiquitin protein ligase binding|metal ion binding|C3HC4-type RING finger domain binding|",10,0.1,0.233,10,0.3,1.03,0.2,0.967,0.967,0.532,0,0,-1,1.7
ENSMUSG00000024885,ALDH3B1,"aldehyde dehydrogenase 3 family, member B1",cytoplasm|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,cellular aldehyde metabolic process|metabolic process|cellular response to oxidative stress|aldehyde catabolic process|oxidation-reduction process|,"aldehyde dehydrogenase [NAD(P)+] activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|",10,-0.3,1.17,10,-0.1,0.185,-0.2,0.963,-0.963,0.533,0,0,-1.7,1
ENSMUSG00000022552,SHARPIN,SHANK-associated RH domain interacting protein,cytoplasm|cytosol|postsynaptic density|cell junction|dendrite|synapse|LUBAC complex|,mitochondrion organization|epidermis development|regulation of tumor necrosis factor-mediated signaling pathway|regulation of tumor necrosis factor-mediated signaling pathway|apoptotic nuclear changes|keratinization|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of inflammatory response|protein homooligomerization|protein linear polyubiquitination|regulation of CD40 signaling pathway|,protein binding|zinc ion binding|polyubiquitin binding|protein complex binding|identical protein binding|metal ion binding|,10,0,0,10,-0.8,3.61,-0.2,0.961,-0.961,0.533,0,0,-2,0.4
ENSMUSG00000030272,CAMK1,calcium/calmodulin-dependent protein kinase I,intracellular|cell|nucleus|cytoplasm|calcium- and calmodulin-dependent protein kinase complex|,protein phosphorylation|protein phosphorylation|protein phosphorylation|nucleocytoplasmic transport|nucleocytoplasmic transport|cell cycle|signal transduction|multicellular organismal development|nervous system development|metabolic process|positive regulation of neuron projection development|phosphorylation|cell differentiation|regulation of protein localization|regulation of protein binding|positive regulation of protein export from nucleus|regulation of muscle cell differentiation|positive regulation of muscle cell differentiation|positive regulation of synapse structural plasticity|positive regulation of dendritic spine development|positive regulation of protein serine/threonine kinase activity|,"nucleotide binding|catalytic activity|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.3,1.71,10,0.1,0.102,0.2,0.961,0.961,0.533,0,0,-1.4,1.3
ENSMUSG00000028692,AKR1A1,"aldo-keto reductase family 1, member A1 (aldehyde reductase)",extracellular space|cytosol|apical plasma membrane|extracellular vesicular exosome|,L-ascorbic acid biosynthetic process|D-glucuronate catabolic process|aldehyde catabolic process|oxidation-reduction process|,alditol:NADP+ 1-oxidoreductase activity|alditol:NADP+ 1-oxidoreductase activity|alditol:NADP+ 1-oxidoreductase activity|alcohol dehydrogenase (NADP+) activity|oxidoreductase activity|L-glucuronate reductase activity|,10,-0.3,1.46,10,0,0,-0.2,0.955,-0.955,0.534,0,0,-1.6,1.1
ENSMUSG00000015932,DSTN,destrin,intracellular|cytoplasm|actin cytoskeleton|cortical actin cytoskeleton|extracellular vesicular exosome|,cytokinesis|cellular component movement|actin filament depolymerization|positive regulation of actin filament depolymerization|,actin binding|,10,0.1,0.357,10,1.1,3.58,0.1,0.947,0.947,0.536,0,0,-0.3,2
ENSMUSG00000026558,UCK2,uridine-cytidine kinase 2,cytosol|intracellular membrane-bounded organelle|,metabolic process|nucleotide biosynthetic process|phosphorylation|,nucleotide binding|uridine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|nucleoside kinase activity|,10,0.5,3.41,10,-0.1,0.245,0.5,0.93,0.93,0.54,0,0,-1.1,1.6
ENSMUSG00000046947,ADCK2,aarF domain containing kinase 2,mitochondrion|membrane|integral component of membrane|,biological_process|phosphorylation|,"nucleotide binding|molecular_function|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|ATP binding|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,-0.3,1.51,10,0,0,-0.2,0.923,-0.923,0.541,0,0,-1.8,0.8
ENSMUSG00000006740,KIF5B,kinesin family member 5B,intracellular|cell|cytoplasm|cytoplasm|microtubule organizing center|cytoskeleton|kinesin complex|microtubule|membrane|endocytic vesicle|vesicle|ciliary rootlet|neuron projection|membrane-bounded organelle|perinuclear region of cytoplasm|,mitochondrial transport|microtubule-based process|microtubule-based movement|cytoplasm organization|metabolic process|stress granule disassembly|regulation of membrane potential|positive regulation of potassium ion transport|vesicle transport along microtubule|vesicle transport along microtubule|plus-end-directed vesicle transport along microtubule|positive regulation of establishment of protein localization to plasma membrane|,nucleotide binding|microtubule motor activity|microtubule motor activity|protein binding|ATP binding|microtubule binding|,10,0.2,1.05,10,0.1,0.0128,0.2,0.919,0.919,0.542,0,0,-1.4,1.5
ENSMUSG00000029919,HPGDS,hematopoietic prostaglandin D synthase,cytoplasm|,prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|prostaglandin metabolic process|,magnesium ion binding|glutathione transferase activity|prostaglandin-D synthase activity|prostaglandin-D synthase activity|calcium ion binding|transferase activity|isomerase activity|protein homodimerization activity|,10,0.8,2.36,9,-0.7,0.342,0.6,0.916,0.916,0.542,0,0,-1.2,1.9
ENSMUSG00000001211,AGPAT3,1-acylglycerol-3-phosphate O-acyltransferase 3,nucleus|endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|,lipid metabolic process|metabolic process|phospholipid biosynthetic process|,"1-acylglycerol-3-phosphate O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.2,0.757,10,0.1,0.246,0.2,0.916,0.916,0.542,0,0,-1.1,1.6
ENSMUSG00000034997,HTR2A,5-hydroxytryptamine (serotonin) receptor 2A,cytoplasm|cytosol|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|dendrite|cytoplasmic vesicle|cell projection|neuronal cell body|dendritic shaft|cell body fiber|,"temperature homeostasis|cellular calcium ion homeostasis|smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|activation of phospholipase C activity|positive regulation of cytosolic calcium ion concentration|phospholipase C-activating serotonin receptor signaling pathway|serotonin receptor signaling pathway|behavior|memory|cell death|positive regulation of cell proliferation|positive regulation of phosphatidylinositol biosynthetic process|regulation of dopamine secretion|phosphatidylinositol 3-kinase signaling|artery smooth muscle contraction|urinary bladder smooth muscle contraction|sensory perception of pain|sleep|positive regulation of kinase activity|response to drug|negative regulation of potassium ion transport|positive regulation of MAP kinase activity|protein localization to cytoskeleton|positive regulation of glycolytic process|positive regulation of vasoconstriction|regulation of hormone secretion|behavioral response to cocaine|positive regulation of peptidyl-tyrosine phosphorylation|regulation of behavior|detection of temperature stimulus involved in sensory perception of pain|detection of mechanical stimulus involved in sensory perception of pain|release of sequestered calcium ion into cytosol|negative regulation of synaptic transmission, glutamatergic|positive regulation of ERK1 and ERK2 cascade|","G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|drug binding|protein complex binding|serotonin binding|1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding|",10,0.1,0.0423,10,-1,3.7,-0.9,0.909,-0.909,0.544,0,0,-2,0.6
ENSMUSG00000020261,SLC36A1,"solute carrier family 36 (proton/amino acid symporter), member 1",lysosome|lysosome|lysosomal membrane|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|neutral amino acid transport|L-alanine transport|glycine transport|proline transport|proton transport|proton transport|proline transmembrane transport|L-alpha-amino acid transmembrane transport|hydrogen ion transmembrane transport|,hydrogen:amino acid symporter activity|hydrogen ion transmembrane transporter activity|neutral amino acid transmembrane transporter activity|L-alanine transmembrane transporter activity|glycine transmembrane transporter activity|L-proline transmembrane transporter activity|symporter activity|,10,1.4,3.04,10,0.3,1.33,0.2,0.908,0.908,0.544,0,0,-0.1,3
ENSMUSG00000030409,DMPK,dystrophia myotonica-protein kinase,intracellular|nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|endoplasmic reticulum|endoplasmic reticulum membrane|cytosol|plasma membrane|membrane|integral component of membrane|sarcoplasmic reticulum|integral component of mitochondrial outer membrane|integral component of mitochondrial outer membrane|nuclear membrane|sarcoplasmic reticulum membrane|,regulation of sodium ion transport|protein phosphorylation|cellular calcium ion homeostasis|nuclear envelope organization|nuclear envelope organization|regulation of heart contraction|regulation of heart contraction|muscle cell apoptotic process|regulation of myotube differentiation|regulation of skeletal muscle contraction by calcium ion signaling|regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction|phosphorylation|regulation of catalytic activity|regulation of synapse structural plasticity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|myosin phosphatase regulator activity|heat shock protein binding|metal ion binding|",10,0,0,10,-0.2,1.34,-0.2,0.907,-0.907,0.544,0,0,-1.7,0.9
ENSMUSG00000020190,MKNK2,MAP kinase-interacting serine/threonine kinase 2,intracellular|nucleus|cytoplasm|,regulation of translation|protein phosphorylation|protein phosphorylation|apoptotic process|phosphorylation|hemopoiesis|intracellular signal transduction|intracellular signal transduction|cellular response to arsenic-containing substance|extrinsic apoptotic signaling pathway in absence of ligand|extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.2,0.309,10,-0.4,0.845,-0.3,0.885,-0.885,0.549,0,0,-1.8,0.7
ENSMUSG00000010154,SPIRE2,spire homolog 2 (Drosophila),intracellular|cell|cytoplasm|cytoskeleton|plasma membrane|cell cortex|membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle|cleavage furrow|,transport|protein transport|vesicle-mediated transport|actin cytoskeleton organization|actin cytoskeleton organization|cleavage furrow formation|polar body extrusion after meiotic divisions|intracellular transport|establishment of meiotic spindle localization|establishment of meiotic spindle localization|formin-nucleated actin cable assembly|,molecular_function|actin binding|,10,-0.3,0.43,10,-0.1,0.549,-0.2,0.875,-0.875,0.551,0,0,-1.8,0.7
ENSMUSG00000024665,FADS2,fatty acid desaturase 2,endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|transport|oxidation-reduction process|,"stearoyl-CoA 9-desaturase activity|iron ion binding|acyl-CoA desaturase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water|heme binding|",10,0.2,0.593,10,0.6,1.53,0.2,0.874,0.874,0.552,0,0,-0.3,2
ENSMUSG00000042854,TRP53RK,transformation related protein 53 regulating kinase,nucleus|,protein phosphorylation|,p53 binding|protein serine/threonine kinase activity|,10,-0.3,0.899,10,0.5,0.518,0.2,0.848,0.848,0.557,0,0,-1.1,1.7
ENSMUSG00000019893,ROS1,Ros1 proto-oncogene,plasma membrane|membrane|integral component of membrane|,columnar/cuboidal epithelial cell development|protein phosphorylation|protein phosphorylation|spermatogenesis|cell proliferation|negative regulation of gene expression|regulation of phosphate transport|cell growth|phosphorylation|peptidyl-tyrosine phosphorylation|cell differentiation|regulation of TOR signaling|regulation of ERK1 and ERK2 cascade|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|protein phosphatase binding|",10,-0.4,2.34,10,0.1,0.399,0.2,0.848,0.848,0.557,0,0,-1.5,1.3
ENSMUSG00000032279,IDH3A,isocitrate dehydrogenase 3 (NAD+) alpha,nucleus|mitochondrion|mitochondrion|,tricarboxylic acid cycle|isocitrate metabolic process|2-oxoglutarate metabolic process|NADH metabolic process|oxidation-reduction process|,"magnesium ion binding|isocitrate dehydrogenase (NAD+) activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|metal ion binding|NAD binding|",10,0.4,0.68,10,-0.4,2.75,-0.3,0.846,-0.846,0.558,0,0,-1.5,1.4
ENSMUSG00000026447,PIK3C2B,"phosphoinositide-3-kinase, class 2, beta polypeptide",plasma membrane|phosphatidylinositol 3-kinase complex|endocytic vesicle|,phosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|protein kinase B signaling|lipid phosphorylation|phosphatidylinositol phosphorylation|,nucleotide binding|lipid kinase activity|protein binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|1-phosphatidylinositol-4-phosphate 3-kinase activity|,10,0.4,0.898,10,0.4,0.00358,0.4,0.835,0.835,0.56,0,0,-0.7,1.8
ENSMUSG00000075552,CYP3A41B,"cytochrome P450, family 3, subfamily a, polypeptide 41B",cellular_component|endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|demethylation|,oxidoreductase activity|demethylase activity|testosterone 6-beta-hydroxylase activity|,10,0.4,1.51,10,-0.1,0.106,0.2,0.817,0.817,0.565,0,0,-1.1,1.7
ENSMUSG00000074483,BGLAP,bone gamma carboxyglutamate protein,extracellular region|extracellular space|cytoplasm|cytoplasm|rough endoplasmic reticulum|Golgi apparatus|dendrite|membrane-bounded vesicle|cell projection|perikaryon|,regulation of bone mineralization|biomineral tissue development|,calcium ion binding|structural constituent of bone|metal ion binding|,10,0,0,10,-0.2,1.85,-0.2,0.812,-0.812,0.566,0,0,-1.7,0.9
ENSMUSG00000030344,AKAP3,A kinase (PRKA) anchor protein 3,acrosomal vesicle|nucleus|cytoplasmic vesicle|motile cilium|sperm fibrous sheath|sperm principal piece|,cellular component movement|transmembrane receptor protein serine/threonine kinase signaling pathway|protein localization|,protein binding|protein kinase A binding|,10,0.2,1.06,10,0,0,0.1,0.802,0.802,0.568,0,0,-1.6,1.4
ENSMUSG00000050063,KLK6,kallikrein related-peptidase 6,extracellular region|extracellular space|nucleus|cytoplasm|microtubule cytoskeleton|nuclear membrane|intercellular bridge|,proteolysis|regulation of neuron projection development|positive regulation of G-protein coupled receptor protein signaling pathway|neuron death|,serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.252,10,-0.6,2.99,-0.4,0.8,-0.8,0.569,0,0,-1.9,0.8
ENSMUSG00000030310,SLC6A1,"solute carrier family 6 (neurotransmitter transporter, GABA), member 1",plasma membrane|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|axon|neuron projection|,"amino acid transmembrane transport|transport|neurotransmitter transport|learning|response to toxic substance|response to organic substance|positive regulation of gamma-aminobutyric acid secretion|response to purine-containing compound|negative regulation of synaptic transmission, GABAergic|sodium ion transmembrane transport|protein homooligomerization|gamma-aminobutyric acid import|",neurotransmitter:sodium symporter activity|gamma-aminobutyric acid:sodium symporter activity|symporter activity|,10,0,0,10,0.6,2.66,0.5,0.799,0.799,0.569,0,0,-0.7,1.9
ENSMUSG00000026626,PPP2R5A,"protein phosphatase 2, regulatory subunit B', alpha","protein phosphatase type 2A complex|chromosome, centromeric region|nucleus|chromosome|cytoplasm|membrane|Z disc|M band|",signal transduction|positive regulation of protein dephosphorylation|negative regulation of establishment of protein localization to plasma membrane|negative regulation of lipid kinase activity|,protein binding|protein phosphatase type 2A regulator activity|kinase binding|,10,1,1.97,10,-0.3,0.914,-0.2,0.789,-0.789,0.571,0,0,-0.9,2
ENSMUSG00000071489,PTGDR,prostaglandin D receptor,plasma membrane|plasma membrane|membrane|integral component of membrane|,inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|male sex determination|sleep|adenosine metabolic process|cellular response to prostaglandin D stimulus|,prostaglandin J receptor activity|signal transducer activity|G-protein coupled receptor activity|prostaglandin D receptor activity|prostaglandin D receptor activity|,10,0.3,1.4,10,-0.3,0.572,0.3,0.787,0.787,0.572,0,0,-1.3,1.5
ENSMUSG00000028541,B4GALT2,"UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2",Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity|N-acetyllactosamine synthase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|lactose synthase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.4,2.5,10,0,0,0.3,0.779,0.779,0.573,0,0,-0.6,2
ENSMUSG00000028072,NTRK1,"neurotrophic tyrosine kinase, receptor, type 1",cytoplasm|endosome|early endosome|late endosome|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|axon|dendrite|cytoplasmic vesicle|neuronal cell body|protein complex|receptor complex|,"protein phosphorylation|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|axon guidance|learning or memory|developmental programmed cell death|response to activity|phosphorylation|peptidyl-tyrosine phosphorylation|sensory perception of pain|cell differentiation|B cell differentiation|response to nutrient levels|response to nicotine|nerve growth factor signaling pathway|mechanoreceptor differentiation|response to drug|positive regulation of programmed cell death|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of angiogenesis|protein autophosphorylation|neurotrophin TRK receptor signaling pathway|sympathetic nervous system development|detection of temperature stimulus involved in sensory perception of pain|detection of mechanical stimulus involved in sensory perception of pain|positive regulation of NF-kappaB transcription factor activity|response to electrical stimulus|positive regulation of synaptic transmission, glutamatergic|Sertoli cell development|axonogenesis involved in innervation|cellular response to nicotine|cellular response to growth factor stimulus|negative regulation of neuron death|cellular response to nerve growth factor stimulus|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|neurotrophin receptor activity|neurotrophin p75 receptor binding|protein binding|ATP binding|nerve growth factor receptor activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|ephrin receptor binding|nerve growth factor binding|",10,0.4,1.66,10,-0.1,0.245,0.3,0.77,0.77,0.575,0,0,-0.7,1.9
ENSMUSG00000047759,HS3ST3A1,heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|sulfotransferase activity|[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity|transferase activity|,10,1.5,4.15,10,-0.1,0.0417,1.4,0.77,0.77,0.575,0,0,-0.3,3
ENSMUSG00000019320,NOXO1,NADPH oxidase organizer 1,plasma membrane|membrane|NADPH oxidase complex|,superoxide metabolic process|extracellular matrix disassembly|positive regulation of catalytic activity|,lipid binding|superoxide-generating NADPH oxidase activator activity|enzyme binding|phosphatidylinositol binding|identical protein binding|,10,-0.2,0.592,10,-0.7,0.583,-0.3,0.768,-0.768,0.576,0,0,-1.9,0.5
ENSMUSG00000025003,CYP2C39,"cytochrome P450, family 2, subfamily c, polypeptide 39",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|caffeine oxidase activity|metal ion binding|aromatase activity|",10,1,1.29,10,-0.3,1.27,-0.6,0.762,-0.762,0.577,0,0,-1.6,1.7
ENSMUSG00000025328,PADI3,"peptidyl arginine deiminase, type III",cytoplasm|,cellular protein modification process|protein citrullination|,protein-arginine deiminase activity|protein-arginine deiminase activity|calcium ion binding|hydrolase activity|,10,0,0,10,0.3,1.08,0.2,0.76,0.76,0.577,0,0,-0.8,1.8
ENSMUSG00000026988,WDSUB1,"WD repeat, SAM and U-box domain containing 1",cellular_component|,biological_process|protein ubiquitination|,molecular_function|ubiquitin-protein transferase activity|,10,0.2,1.83,10,0,0,0.2,0.756,0.756,0.578,0,0,-1.1,1.6
ENSMUSG00000039616,MOCOS,molybdenum cofactor sulfurase,cellular_component|,Mo-molybdopterin cofactor biosynthetic process|metabolic process|molybdopterin cofactor metabolic process|,catalytic activity|Mo-molybdopterin cofactor sulfurase activity|transferase activity|molybdenum ion binding|pyridoxal phosphate binding|,10,0.3,0.565,10,-0.7,2.19,-0.1,0.741,-0.741,0.582,0,0,-2,0.7
ENSMUSG00000021501,CAML,calcium modulating ligand,endoplasmic reticulum|membrane|membrane|integral component of membrane|,receptor recycling|epidermal growth factor receptor signaling pathway|,protein binding|cell adhesion molecule binding|,10,1,0.689,9,0.2,0.957,0.2,0.74,0.74,0.582,0,0,-1,2
ENSMUSG00000000628,HK2,hexokinase 2,mitochondrion|mitochondrion|mitochondrial outer membrane|cytosol|membrane|,cellular glucose homeostasis|response to ischemia|carbohydrate metabolic process|glucose metabolic process|glycolytic process|metabolic process|apoptotic mitochondrial changes|apoptotic mitochondrial changes|phosphorylation|regulation of glucose import|carbohydrate phosphorylation|carbohydrate phosphorylation|carbohydrate phosphorylation|glucose 6-phosphate metabolic process|,"nucleotide binding|catalytic activity|glucokinase activity|hexokinase activity|hexokinase activity|hexokinase activity|ATP binding|glucose binding|fructokinase activity|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|mannokinase activity|",10,0.2,0.234,10,0.6,1.61,0.2,0.738,0.738,0.583,0,0,-0.7,2
ENSMUSG00000003283,HCK,hemopoietic cell kinase,nucleus|cytoplasm|lysosome|Golgi apparatus|cytoskeleton|actin filament|plasma membrane|caveola|focal adhesion|membrane|cell junction|extrinsic component of cytoplasmic side of plasma membrane|cytoplasmic vesicle|cell projection|,immune system process|protein phosphorylation|exocytosis|phagocytosis|inflammatory response|positive regulation of cell proliferation|regulation of cell shape|phosphorylation|peptidyl-tyrosine phosphorylation|negative regulation of apoptotic process|innate immune response|protein autophosphorylation|regulation of phagocytosis|defense response to Gram-positive bacterium|regulation of sequence-specific DNA binding transcription factor activity|regulation of podosome assembly|positive regulation of actin cytoskeleton reorganization|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.4,2.82,10,0.1,0.0533,-0.3,0.719,-0.719,0.588,0,0,-1.5,1.2
ENSMUSG00000025161,SLC16A3,"solute carrier family 16 (monocarboxylic acid transporters), member 3",plasma membrane|actin cytoskeleton|membrane|integral component of membrane|nuclear membrane|,transport|organic anion transport|plasma membrane lactate transport|transmembrane transport|,symporter activity|secondary active monocarboxylate transmembrane transporter activity|poly(A) RNA binding|,10,0.3,2.75,10,0,0,0.3,0.714,0.714,0.589,0,0,-0.6,1.9
ENSMUSG00000025584,PDE8A,phosphodiesterase 8A,extracellular vesicular exosome|,phosphorelay signal transduction system|signal transduction|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|signal transducer activity|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|",10,0.7,3.07,10,-0.1,0.092,0.3,0.71,0.71,0.59,0,0,-0.6,1.9
ENSMUSG00000000934,TOP1MT,"DNA topoisomerase 1, mitochondrial",nucleus|chromosome|mitochondrion|mitochondrion|mitochondrial nucleoid|mitochondrial nucleoid|,DNA replication|DNA topological change|,DNA binding|DNA topoisomerase activity|DNA topoisomerase type I activity|DNA topoisomerase type II (ATP-hydrolyzing) activity|isomerase activity|,10,0.2,0.693,10,-0.3,1.61,-0.2,0.71,-0.71,0.59,0,0,-1.3,1.5
ENSMUSG00000062168,PPEF1,protein phosphatase with EF hand calcium-binding domain 1,None,dephosphorylation|detection of stimulus involved in sensory perception|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|iron ion binding|calcium ion binding|hydrolase activity|manganese ion binding|metal ion binding|,9,-0.3,1.08,9,0.5,0.287,-0.3,0.709,-0.709,0.59,0,0,-1.7,1.3
ENSMUSG00000050578,MMP13,matrix metallopeptidase 13,extracellular region|proteinaceous extracellular matrix|fibrillar collagen trimer|extracellular space|lysosome|Golgi apparatus|extracellular matrix|intercellular canaliculus|,endochondral ossification|proteolysis|proteolysis|proteolysis|extracellular matrix disassembly|extracellular matrix disassembly|bone mineralization|collagen catabolic process|collagen catabolic process|collagen catabolic process|receptor internalization|peptide catabolic process|cellular protein metabolic process|cartilage development|bone morphogenesis|,fibronectin binding|metalloendopeptidase activity|metalloendopeptidase activity|calcium ion binding|collagen binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|calcium-dependent protein binding|low-density lipoprotein particle receptor binding|,10,1.1,2.95,10,-0.1,0.427,1.1,0.698,0.698,0.593,0,0,-0.4,2
ENSMUSG00000020447,NPC1L1,NPC1-like 1,plasma membrane|membrane|integral component of membrane|brush border membrane|,lipid metabolic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|intestinal cholesterol absorption|cholesterol transport|lipoprotein metabolic process|cholesterol homeostasis|,drug binding|hedgehog receptor activity|Rab GTPase binding|myosin V binding|,10,0.3,0.679,10,1.4,1.55,0.1,0.693,0.693,0.594,0,0,-0.6,3
ENSMUSG00000018401,MTMR4,myotubularin related protein 4,extracellular space|cytoplasm|membrane|,dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|,10,0,0,10,0.2,1.89,0.2,0.691,0.691,0.595,0,0,-1.1,1.6
ENSMUSG00000020682,MMP28,matrix metallopeptidase 28 (epilysin),cytoplasm|,proteolysis|negative regulation of macrophage chemotaxis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.2,1.92,10,-0.1,0.0905,0.1,0.689,0.689,0.596,0,0,-0.9,1.8
ENSMUSG00000032860,P2RY2,"purinergic receptor P2Y, G-protein coupled 2",mitochondrion|lysosome|early endosome|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|,signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of neuron projection development|positive regulation of smooth muscle cell migration|sensory perception of pain|negative regulation of ossification|positive regulation of prostaglandin secretion|positive regulation of chemokine production|regulation of vasodilation|positive regulation of penile erection|positive regulation of mucus secretion|,signal transducer activity|G-protein coupled receptor activity|ATP binding|A1 adenosine receptor binding|G-protein coupled purinergic nucleotide receptor activity|UTP-activated nucleotide receptor activity|,10,0.2,0.479,10,0.1,0.333,0.1,0.689,0.689,0.596,0,0,-1.2,1.6
ENSMUSG00000018001,CYTH3,cytohesin 3,ruffle|cytoplasm|cytosol|plasma membrane|plasma membrane|membrane|extrinsic component of cytoplasmic side of plasma membrane|,regulation of ARF protein signal transduction|positive regulation of GTPase activity|positive regulation of GTPase activity|positive regulation of cell adhesion|Golgi vesicle transport|establishment of epithelial cell polarity|,"guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|protein binding|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|lipid binding|",10,-0.2,0.538,10,0.2,1.35,0.1,0.687,0.687,0.596,0,0,-1.4,1.4
ENSMUSG00000024462,GABBR1,"gamma-aminobutyric acid (GABA) B receptor, 1",extracellular space|cytoplasm|endoplasmic reticulum membrane|plasma membrane|integral component of plasma membrane|synaptic vesicle|membrane|integral component of membrane|cell junction|axolemma|mitochondrial membrane|G-protein coupled receptor dimeric complex|G-protein coupled receptor heterodimeric complex|presynaptic membrane|cell projection|neuron projection|neuronal cell body|dendritic spine|dendritic shaft|intracellular membrane-bounded organelle|membrane raft|synapse|postsynaptic membrane|,osteoblast differentiation|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|gamma-aminobutyric acid signaling pathway|gamma-aminobutyric acid signaling pathway|negative regulation of cell proliferation|regulation of glutamate secretion|positive regulation of glutamate secretion|negative regulation of gamma-aminobutyric acid secretion|regulation of cAMP biosynthetic process|negative regulation of epinephrine secretion|negative regulation of dopamine secretion|negative regulation of synaptic transmission|positive regulation of growth hormone secretion|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled GABA receptor activity|G-protein coupled GABA receptor activity|protein binding|transcription factor binding|,9,0.3,0.424,8,0.4,0.324,0.3,0.678,0.678,0.599,0,0,-1,1.9
ENSMUSG00000026620,MARK1,MAP/microtubule affinity-regulating kinase 1,cytoplasm|cytoskeleton|plasma membrane|membrane|,microtubule cytoskeleton organization|neuron migration|protein phosphorylation|cytoskeleton organization|Wnt signaling pathway|phosphorylation|intracellular signal transduction|,"nucleotide binding|magnesium ion binding|phosphatidylserine binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|tau-protein kinase activity|phosphatidic acid binding|",10,0.2,1.54,10,0,0,0.2,0.677,0.677,0.599,0,0,-1.1,1.6
ENSMUSG00000026274,PASK,PAS domain containing serine/threonine kinase,intracellular|nucleus|cytoplasm|Golgi apparatus|,protein phosphorylation|signal transduction|phosphorylation|regulation of respiratory gaseous exchange|negative regulation of glycogen biosynthetic process|protein autophosphorylation|regulation of glucagon secretion|regulation of energy homeostasis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|signal transducer activity|ATP binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphatidylinositol binding|",10,0,0,10,-0.2,1.41,-0.2,0.672,-0.672,0.6,0,0,-1.6,1.2
ENSMUSG00000024620,PDGFRB,"platelet derived growth factor receptor, beta polypeptide",nucleus|cytoplasm|cytoplasm|lysosome|plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|intrinsic component of plasma membrane|cytoplasmic vesicle|extracellular vesicular exosome|,in utero embryonic development|kidney development|tissue homeostasis|glycosaminoglycan biosynthetic process|protein phosphorylation|nitrogen compound metabolic process|chemotaxis|signal transduction|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|positive regulation of cell proliferation|positive regulation of phospholipase C activity|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of smooth muscle cell migration|positive regulation of smooth muscle cell migration|positive regulation of smooth muscle cell migration|phosphorylation|cell migration|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|adrenal gland development|positive regulation of cell migration|positive regulation of phosphoprotein phosphatase activity|regulation of actin cytoskeleton organization|positive regulation of collagen biosynthetic process|cell migration involved in vasculogenesis|intracellular signal transduction|metanephric mesenchymal cell migration|platelet-derived growth factor receptor-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway|aorta morphogenesis|cellular response to platelet-derived growth factor stimulus|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway|negative regulation of apoptotic process|positive regulation of MAP kinase activity|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of mitosis|phosphatidylinositol metabolic process|protein autophosphorylation|protein autophosphorylation|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of smooth muscle cell proliferation|positive regulation of smooth muscle cell proliferation|skeletal system morphogenesis|smooth muscle tissue development|regulation of peptidyl-tyrosine phosphorylation|positive regulation of chemotaxis|cardiac myofibril assembly|cell chemotaxis|cardiac vascular smooth muscle cell differentiation|cell migration involved in coronary angiogenesis|retina vasculature development in camera-type eye|retina vasculature development in camera-type eye|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|smooth muscle cell chemotaxis|metanephric glomerular mesangial cell proliferation involved in metanephros development|metanephric glomerular capillary formation|positive regulation of calcium ion import|positive regulation of reactive oxygen species metabolic process|positive regulation of DNA biosynthetic process|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|signal transducer activity|platelet-derived growth factor-activated receptor activity|platelet-derived growth factor beta-receptor activity|receptor binding|receptor binding|platelet-derived growth factor receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|vascular endothelial growth factor binding|phosphatidylinositol 3-kinase binding|platelet-derived growth factor binding|platelet-derived growth factor binding|",10,0.1,0.066,10,-0.3,2.23,-0.2,0.669,-0.669,0.601,0,0,-1.6,1
ENSMUSG00000021948,PRKCD,"protein kinase C, delta",nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|endoplasmic reticulum|cytosol|plasma membrane|cell-cell junction|membrane|nuclear matrix|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|apoptotic process|response to oxidative stress|cell cycle|aspartate transport|immunoglobulin mediated immune response|phosphorylation|peptidyl-threonine phosphorylation|termination of signal transduction|negative regulation of actin filament polymerization|interleukin-10 production|interleukin-12 production|positive regulation of superoxide anion generation|collagen metabolic process|negative regulation of glial cell apoptotic process|positive regulation of protein dephosphorylation|intracellular signal transduction|B cell proliferation|neutrophil activation|defense response to bacterium|positive regulation of apoptotic process|positive regulation of MAP kinase activity|negative regulation of MAP kinase activity|positive regulation of MAPK cascade|positive regulation of glucose import|negative regulation of insulin receptor signaling pathway|protein autophosphorylation|negative regulation of peptidyl-tyrosine phosphorylation|negative regulation of filopodium assembly|negative regulation of platelet aggregation|cellular senescence|positive regulation of phospholipid scramblase activity|positive regulation of ceramide biosynthetic process|positive regulation of glucosylceramide catabolic process|positive regulation of sphingomyelin catabolic process|positive regulation of response to DNA damage stimulus|positive regulation of apoptotic signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|calcium-independent protein kinase C activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|enzyme activator activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|protein kinase binding|insulin receptor substrate binding|metal ion binding|TIR domain binding|",10,-0.4,1.54,10,0,0,-0.2,0.668,-0.668,0.601,0,0,-1.7,0.9
ENSMUSG00000030742,LAT,linker for activation of T cells,immunological synapse|immunological synapse|intracellular|plasma membrane|integral component of plasma membrane|cell-cell junction|COP9 signalosome|membrane|integral component of membrane|,lymphocyte homeostasis|immune system process|inflammatory response|immune response|cellular defense response|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|integrin-mediated signaling pathway|Ras protein signal transduction|positive regulation of signal transduction|gene expression|calcium-mediated signaling|intracellular signal transduction|intracellular signal transduction|mast cell degranulation|homeostasis of number of cells|regulation of T cell activation|,receptor signaling protein activity|SH3/SH2 adaptor activity|protein binding|protein kinase binding|,10,-0.4,1.92,10,0.2,0.181,-0.2,0.662,-0.662,0.603,0,0,-1.6,1.1
ENSMUSG00000032383,PPIB,peptidylprolyl isomerase B,nucleus|endoplasmic reticulum|smooth endoplasmic reticulum|membrane|extracellular vesicular exosome|,protein peptidyl-prolyl isomerization|protein folding|positive regulation of multicellular organism growth|protein stabilization|bone development|,peptidyl-prolyl cis-trans isomerase activity|isomerase activity|peptide binding|poly(A) RNA binding|,10,0.1,0.0258,10,0.2,0.753,0.2,0.662,0.662,0.603,0,0,-0.9,1.7
ENSMUSG00000039682,LAP3,leucine aminopeptidase 3,intracellular|nucleus|cytoplasm|mitochondrion|trans-Golgi network|extracellular vesicular exosome|,proteolysis|protein metabolic process|,aminopeptidase activity|peptidase activity|metalloexopeptidase activity|hydrolase activity|manganese ion binding|metal ion binding|,10,-0.8,3.3,10,0,0,-0.7,0.66,-0.66,0.603,0,0,-2,0.5
ENSMUSG00000019960,DUSP6,dual specificity phosphatase 6,cytoplasm|cytosol|,inactivation of MAPK activity|negative regulation of protein phosphorylation|protein dephosphorylation|protein dephosphorylation|dorsal/ventral pattern formation|positive regulation of cell death|dephosphorylation|peptidyl-tyrosine dephosphorylation|regulation of fibroblast growth factor receptor signaling pathway|regulation of endodermal cell fate specification|positive regulation of apoptotic process|positive regulation of apoptotic process|regulation of heart growth|negative regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 and ERK2 cascade|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,10,0.2,1.23,10,0,0,0.1,0.658,0.658,0.604,0,0,-1,1.7
ENSMUSG00000025855,PRKAR1B,"protein kinase, cAMP dependent regulatory, type I beta",cytoplasm|cytoplasm|plasma membrane|cAMP-dependent protein kinase complex|membrane|,regulation of protein phosphorylation|protein phosphorylation|learning or memory|cell proliferation|organ morphogenesis|phosphorylation|regulation of protein kinase activity|regulation of protein kinase activity|negative regulation of cAMP-dependent protein kinase activity|,nucleotide binding|cAMP-dependent protein kinase inhibitor activity|cAMP-dependent protein kinase regulator activity|cAMP-dependent protein kinase regulator activity|kinase activity|transferase activity|cAMP binding|protein kinase A catalytic subunit binding|,10,-0.3,0.702,10,0.4,2.79,0.4,0.656,0.656,0.604,0,0,-1.1,1.7
ENSMUSG00000075551,CYP3A41A,"cytochrome P450, family 3, subfamily a, polypeptide 41A",endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,regulation of gene expression|oxidation-reduction process|demethylation|,oxidoreductase activity|demethylase activity|testosterone 6-beta-hydroxylase activity|,9,0.5,1.41,9,-0.5,2.03,0.2,0.651,0.651,0.606,0,0,-1.4,1.6
ENSMUSG00000038371,SBF2,SET binding factor 2,vacuolar membrane|membrane|,positive regulation of Rab GTPase activity|regulation of catalytic activity|protein tetramerization|,Rab guanyl-nucleotide exchange factor activity|phosphatase regulator activity|phosphatase binding|phosphatidylinositol binding|protein homodimerization activity|,10,0.2,0.635,10,0.1,0.173,0.2,0.651,0.651,0.606,0,0,-1.2,1.6
ENSMUSG00000072946,PTGR2,prostaglandin reductase 2,cytoplasm|mitochondrion|extracellular vesicular exosome|,prostaglandin metabolic process|oxidation-reduction process|,zinc ion binding|oxidoreductase activity|13-prostaglandin reductase activity|15-oxoprostaglandin 13-oxidase activity|,10,0.1,0.0543,10,0.3,0.995,0.2,0.644,0.644,0.608,0,0,-0.8,1.8
ENSMUSG00000070738,DGKD,"diacylglycerol kinase, delta",cytoplasm|plasma membrane|cytoplasmic membrane-bounded vesicle|,response to organic substance|phosphorylation|diacylglycerol metabolic process|protein homooligomerization|,nucleotide binding|diacylglycerol kinase activity|ATP binding|kinase activity|transferase activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,0.3,0.979,10,0,0,0.3,0.642,0.642,0.608,0,0,-0.9,1.8
ENSMUSG00000052539,MAGI3,"membrane associated guanylate kinase, WW and PDZ domain containing 3",nucleus|plasma membrane|cell-cell junction|tight junction|membrane|cell junction|,phosphorylation|positive regulation of JUN kinase activity|,nucleotide binding|frizzled binding|protein binding|ATP binding|kinase activity|transferase activity|,10,0.4,2.34,10,-0.5,2.41,0.3,0.641,0.641,0.608,0,0,-1.6,1.2
ENSMUSG00000031668,EIF2AK3,eukaryotic translation initiation factor 2 alpha kinase 3,intracellular|cell|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,skeletal system development|ossification|chondrocyte development|translation|translational initiation|regulation of translation|protein phosphorylation|protein phosphorylation|protein phosphorylation|activation of cysteine-type endopeptidase activity involved in apoptotic process|response to stress|ER overload response|response to unfolded protein|endoplasmic reticulum organization|lactation|positive regulation of signal transduction|negative regulation of gene expression|phosphorylation|negative regulation of translation|negative regulation of translation|negative regulation of translation|regulation of fatty acid metabolic process|calcium-mediated signaling|bone mineralization|endoplasmic reticulum unfolded protein response|endoplasmic reticulum unfolded protein response|endoplasmic reticulum unfolded protein response|pancreas development|endocrine pancreas development|negative regulation of myelination|negative regulation of translation in response to stress|positive regulation of protein binding|SREBP signaling pathway|response to endoplasmic reticulum stress|negative regulation of apoptotic process|fat cell differentiation|protein autophosphorylation|protein autophosphorylation|protein autophosphorylation|insulin-like growth factor receptor signaling pathway|protein homooligomerization|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,"nucleotide binding|translation initiation factor activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|protein phosphatase binding|identical protein binding|",10,0.1,0.034,10,-0.2,1.38,-0.2,0.639,-0.639,0.609,0,0,-1.7,1
ENSMUSG00000022425,ENPP2,ectonucleotide pyrophosphatase/phosphodiesterase 2,extracellular region|extracellular space|extracellular space|integral component of plasma membrane|,lipid metabolic process|chemotaxis|immune response|metabolic process|phospholipid catabolic process|lipid catabolic process|regulation of cell migration|phosphatidylcholine catabolic process|phosphatidylcholine catabolic process|nucleic acid phosphodiester bond hydrolysis|,nucleic acid binding|catalytic activity|phosphodiesterase I activity|nucleotide diphosphatase activity|lysophospholipase activity|lysophospholipase activity|scavenger receptor activity|calcium ion binding|calcium ion binding|zinc ion binding|zinc ion binding|hydrolase activity|polysaccharide binding|metal ion binding|alkylglycerophosphoethanolamine phosphodiesterase activity|,10,0.1,0.369,10,0.3,0.399,0.1,0.636,0.636,0.61,0,0,-1.6,1.4
ENSMUSG00000030895,HPX,hemopexin,extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,positive regulation of immunoglobulin production|positive regulation of humoral immune response mediated by circulating immunoglobulin|transport|hemoglobin metabolic process|heme metabolic process|positive regulation of tyrosine phosphorylation of Stat1 protein|regulation of protein metabolic process|positive regulation of response to interferon-gamma|positive regulation of interferon-gamma-mediated signaling pathway|,heme binding|metal ion binding|,10,0.4,1.03,10,0.1,0.254,0.2,0.632,0.632,0.611,0,0,-1.2,1.5
ENSMUSG00000027665,PIK3CA,"phosphatidylinositol 3-kinase, catalytic, alpha polypeptide","intracellular|plasma membrane|phosphatidylinositol 3-kinase complex|phosphatidylinositol 3-kinase complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex|lamellipodium|",angiogenesis|glucose metabolic process|protein phosphorylation|phosphorylation|positive regulation of peptidyl-serine phosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol-3-phosphate biosynthetic process|regulation of multicellular organism growth|protein kinase B signaling|negative regulation of neuron apoptotic process|hypomethylation of CpG island|positive regulation of protein kinase activity|phosphatidylinositol phosphorylation|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|negative regulation of fibroblast apoptotic process|regulation of genetic imprinting|negative regulation of anoikis|,"nucleotide binding|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|protein kinase activator activity|1-phosphatidylinositol-4-phosphate 3-kinase activity|insulin receptor substrate binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|",10,-0.2,0.598,10,0.1,0.188,-0.2,0.623,-0.623,0.613,0,0,-1.8,0.8
ENSMUSG00000023210,LCN9,lipocalin 9,cellular_component|extracellular region|,transport|biological_process|,transporter activity|pheromone binding|,10,0,0,10,0.2,1.17,0.2,0.621,0.621,0.614,0,0,-1.8,1.2
ENSMUSG00000042010,ACACB,acetyl-Coenzyme A carboxylase beta,mitochondrion|mitochondrion|,acetyl-CoA metabolic process|fatty acid biosynthetic process|response to organic cyclic compound|protein homotetramerization|,nucleotide binding|acetyl-CoA carboxylase activity|acetyl-CoA carboxylase activity|acetyl-CoA carboxylase activity|ATP binding|biotin binding|ligase activity|,10,0,0,10,-0.2,1.07,-0.2,0.62,-0.62,0.614,0,0,-1.5,1.2
ENSMUSG00000054764,MTNR1A,melatonin receptor 1A,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|circadian rhythm|positive regulation of cGMP biosynthetic process|,signal transducer activity|G-protein coupled receptor activity|melatonin receptor activity|hormone binding|organic cyclic compound binding|,10,0,0,9,-0.2,0.978,-0.2,0.616,-0.616,0.615,0,0,-1.3,1.6
ENSMUSG00000024827,GLDC,glycine decarboxylase,mitochondrion|mitochondrion|glycine cleavage complex|,cellular amino acid metabolic process|glycine metabolic process|glycine catabolic process|glycine decarboxylation via glycine cleavage system|oxidation-reduction process|,catalytic activity|glycine dehydrogenase (decarboxylating) activity|oxidoreductase activity|glycine binding|lyase activity|enzyme binding|pyridoxal phosphate binding|protein homodimerization activity|protein dimerization activity|,10,0,0,10,-0.5,1.93,-0.4,0.607,-0.607,0.618,0,0,-1.5,1.4
ENSMUSG00000032259,DRD2,dopamine receptor D2,acrosomal vesicle|plasma membrane|integral component of plasma membrane|postsynaptic density|membrane|membrane|integral component of membrane|lateral plasma membrane|endocytic vesicle|axon|axon|dendrite|dendrite|synaptic vesicle membrane|cytoplasmic vesicle|sperm flagellum|dendritic spine|perikaryon|axon terminus|,"temperature homeostasis|response to hypoxia|synaptic transmission, dopaminergic|startle response|response to amphetamine|response to amphetamine|neurological system process involved in regulation of systemic arterial blood pressure|regulation of heart rate|regulation of sodium ion transport|G-protein coupled receptor internalization|positive regulation of neuroblast proliferation|positive regulation of receptor internalization|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|adenylate cyclase-inhibiting dopamine receptor signaling pathway|adenylate cyclase-inhibiting dopamine receptor signaling pathway|adenylate cyclase-inhibiting dopamine receptor signaling pathway|adenylate cyclase-inhibiting dopamine receptor signaling pathway|dopamine receptor signaling pathway|dopamine receptor signaling pathway|synaptic transmission|neuron-neuron synaptic transmission|axonogenesis|sensory perception of smell|long-term memory|grooming behavior|locomotory behavior|locomotory behavior|locomotory behavior|adult walking behavior|feeding behavior|protein localization|negative regulation of cell proliferation|negative regulation of cell proliferation|associative learning|visual learning|response to light stimulus|regulation of dopamine secretion|Wnt signaling pathway|cerebral cortex GABAergic interneuron migration|adenohypophysis development|negative regulation of cell migration|peristalsis|peristalsis|adult behavior|regulation of cAMP metabolic process|forebrain development|auditory behavior|activation of protein kinase activity|regulation of synaptic transmission, GABAergic|regulation of synaptic transmission, GABAergic|positive regulation of cytokinesis|circadian regulation of gene expression|negative regulation of dopamine secretion|response to histamine|intracellular signal transduction|positive regulation of urine volume|positive regulation of renal sodium excretion|positive regulation of multicellular organism growth|response to cocaine|response to cocaine|negative regulation of circadian sleep/wake cycle, sleep|dopamine metabolic process|response to drug|response to drug|response to drug|regulation of potassium ion transport|regulation of potassium ion transport|response to morphine|regulation of MAPK cascade|pigmentation|regulation of phosphoprotein phosphatase activity|positive regulation of G-protein coupled receptor protein signaling pathway|negative regulation of blood pressure|positive regulation of transcription from RNA polymerase II promoter|phosphatidylinositol metabolic process|negative regulation of insulin secretion|acid secretion|behavioral response to cocaine|behavioral response to ethanol|regulation of long-term neuronal synaptic plasticity|branching morphogenesis of a nerve|arachidonic acid secretion|negative regulation of protein secretion|regulation of synaptic transmission|regulation of synaptic transmission|release of sequestered calcium ion into cytosol|negative regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|regulation of dopamine uptake involved in synaptic transmission|positive regulation of dopamine uptake involved in synaptic transmission|regulation of synapse structural plasticity|negative regulation of protein kinase B signaling|negative regulation of synaptic transmission, glutamatergic|positive regulation of growth hormone secretion|prepulse inhibition|phospholipase C-activating dopamine receptor signaling pathway|phospholipase C-activating dopamine receptor signaling pathway|phospholipase C-activating dopamine receptor signaling pathway|negative regulation of dopamine receptor signaling pathway|negative regulation of dopamine receptor signaling pathway|positive regulation of ERK1 and ERK2 cascade|regulation of locomotion involved in locomotory behavior|positive regulation of long-term synaptic potentiation|negative regulation of voltage-gated calcium channel activity|","dopamine neurotransmitter receptor activity, coupled via Gi/Go|dopamine neurotransmitter receptor activity, coupled via Gi/Go|dopamine neurotransmitter receptor activity, coupled via Gi/Go|signal transducer activity|G-protein coupled receptor activity|dopamine neurotransmitter receptor activity|dopamine neurotransmitter receptor activity|receptor binding|drug binding|dopamine binding|dopamine binding|ionotropic glutamate receptor binding|identical protein binding|protein homodimerization activity|protein heterodimerization activity|",10,1.4,3.15,10,0.2,0.468,0.1,0.607,0.607,0.618,0,0,-0.4,3
ENSMUSG00000031833,MAST3,microtubule associated serine/threonine kinase 3,cellular_component|,protein phosphorylation|phosphorylation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.2,2.94,10,0.2,0.393,1.2,0.605,0.605,0.618,0,0,-0.3,2
ENSMUSG00000091376,AADACL2,arylacetamide deacetylase-like 2,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.549,10,-0.1,0.182,-0.2,0.604,-0.604,0.618,0,0,-1.6,1.2
ENSMUSG00000032883,ACSL3,acyl-CoA synthetase long-chain family member 3,mitochondrion|mitochondrial outer membrane|peroxisome|endoplasmic reticulum|Golgi apparatus|lipid particle|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|metabolic process|very-low-density lipoprotein particle assembly|positive regulation of Golgi to plasma membrane protein transport|long-chain fatty acid import|positive regulation of secretion|positive regulation of phosphatidylcholine biosynthetic process|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|ATP binding|ligase activity|protein kinase binding|protein domain specific binding|,10,-0.2,0.221,10,0.2,0.807,0.1,0.603,0.603,0.619,0,0,-1.5,1.3
ENSMUSG00000024815,TRPD52L3,tumor protein D52-like 3,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.597,10,-0.1,0.184,-0.1,0.599,-0.599,0.62,0,0,-1.3,1.6
ENSMUSG00000030996,ART1,ADP-ribosyltransferase 1,cell surface|membrane|sarcoplasmic reticulum|anchored component of membrane|,protein ADP-ribosylation|,"NAD+ ADP-ribosyltransferase activity|NAD(P)+-protein-arginine ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.395,10,-0.7,2.31,-0.7,0.595,-0.595,0.621,0,0,-2,0.6
ENSMUSG00000027808,SERP1,stress-associated endoplasmic reticulum protein 1,endoplasmic reticulum|cytoplasmic microtubule|membrane|integral component of membrane|,skeletal system development|glucose metabolic process|protein glycosylation|transport|post-embryonic development|multicellular organismal aging|protein transport|endoplasmic reticulum unfolded protein response|positive regulation of insulin secretion|positive regulation of translation|positive regulation of organ growth|muscle organ morphogenesis|positive regulation of growth hormone secretion|,None,10,-0.1,0.117,10,-0.2,0.652,-0.2,0.59,-0.59,0.622,0,0,-1.6,1.1
ENSMUSG00000026715,SERPINC1,"serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1",extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,"response to nutrient|blood coagulation|hemostasis|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|negative regulation of inflammatory response|regulation of blood coagulation, intrinsic pathway|",protease binding|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|heparin binding|peptidase inhibitor activity|,10,0.3,0.588,10,0.1,0.073,0.3,0.587,0.587,0.623,0,0,-0.9,1.8
ENSMUSG00000022052,PPP2R2A,"protein phosphatase 2, regulatory subunit B, alpha",protein phosphatase type 2A complex|,protein dephosphorylation|signal transduction|response to morphine|,protein serine/threonine phosphatase activity|protein phosphatase type 2A regulator activity|,10,0.1,0.468,9,1.5,2,0.1,0.587,0.587,0.623,0,0,-0.6,3
ENSMUSG00000033825,TPSB2,tryptase beta 2,extracellular region|extracellular space|extracellular matrix|,proteolysis|inflammatory response|,catalytic activity|serine-type endopeptidase activity|protein binding|heparin binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,0.1,0.385,9,-0.4,0.496,-0.2,0.586,-0.586,0.623,0,0,-1.8,1
ENSMUSG00000024402,LTA,lymphotoxin A,extracellular region|extracellular space|membrane|,positive regulation of chronic inflammatory response to antigenic stimulus|positive regulation of humoral immune response mediated by circulating immunoglobulin|transformed cell apoptotic process|inflammatory response|immune response|humoral immune response|cell proliferation|positive regulation of cell proliferation|cellular process|positive regulation of interferon-gamma production|positive regulation of apoptotic process|negative regulation of growth of symbiont in host|negative regulation of fibroblast proliferation|lymph node development|defense response to Gram-positive bacterium|positive regulation of glial cell proliferation|,cytokine activity|tumor necrosis factor receptor binding|protein binding|,10,0,0,10,0.2,0.822,0.2,0.584,0.584,0.624,0,0,-0.9,1.8
ENSMUSG00000025534,GUSB,"glucuronidase, beta",lysosome|lysosome|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,carbohydrate metabolic process|metabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-glucuronidase activity|beta-glucuronidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|",10,0,0,10,-0.2,1.08,-0.2,0.58,-0.58,0.625,0,0,-1.6,1.1
ENSMUSG00000029056,PANK4,pantothenate kinase 4,cytoplasm|,coenzyme A biosynthetic process|phosphorylation|,nucleotide binding|pantothenate kinase activity|ATP binding|kinase activity|transferase activity|,10,-1,2.98,10,0.1,0.36,0.1,0.579,0.579,0.625,0,0,-2,0.9
ENSMUSG00000000049,APOH,apolipoprotein H,extracellular region|extracellular space|extracellular space|cell surface|extracellular matrix|very-low-density lipoprotein particle|high-density lipoprotein particle|chylomicron|extracellular vesicular exosome|,"negative regulation of endothelial cell proliferation|triglyceride metabolic process|blood coagulation|blood coagulation, intrinsic pathway|negative regulation of endothelial cell migration|negative regulation of angiogenesis|regulation of blood coagulation|negative regulation of blood coagulation|organ regeneration|plasminogen activation|negative regulation of myeloid cell apoptotic process|triglyceride transport|negative regulation of smooth muscle cell apoptotic process|positive regulation of lipoprotein lipase activity|regulation of fibrinolysis|negative regulation of fibrinolysis|",glycoprotein binding|phospholipid binding|heparin binding|lipid binding|identical protein binding|lipoprotein lipase activator activity|,10,0.2,0.531,10,0.4,0.198,0.2,0.579,0.579,0.625,0,0,-0.7,1.9
ENSMUSG00000020475,PGAM2,phosphoglycerate mutase 2,nucleus|cytosol|,gluconeogenesis|glycolytic process|glycolytic process|striated muscle contraction|metabolic process|response to inorganic substance|response to mercury ion|,"catalytic activity|bisphosphoglycerate mutase activity|bisphosphoglycerate 2-phosphatase activity|phosphoglycerate mutase activity|phosphoglycerate mutase activity|protein binding|hydrolase activity|isomerase activity|intramolecular transferase activity, phosphotransferases|2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity|cofactor binding|",10,1.5,3.89,10,-0.7,0.144,1.5,0.578,0.578,0.626,0,0,-0.9,3
ENSMUSG00000027559,CAR3,carbonic anhydrase 3,cytoplasm|cytosol|,one-carbon metabolic process|response to oxidative stress|,carbonate dehydratase activity|zinc ion binding|nickel cation binding|lyase activity|metal ion binding|,10,0.5,3.08,10,-0.2,1.12,-0.2,0.576,-0.576,0.626,0,0,-1.3,1.5
ENSMUSG00000031089,SLC6A14,"solute carrier family 6 (neurotransmitter transporter), member 14",integral component of plasma membrane|membrane|integral component of membrane|brush border membrane|extracellular vesicular exosome|,transport|neurotransmitter transport|amino acid transport|response to toxic substance|amine transport|transmembrane transport|,amine transmembrane transporter activity|neurotransmitter:sodium symporter activity|symporter activity|,10,0.6,2.28,10,0,0,0.2,0.572,0.572,0.627,0,0,-0.7,1.9
ENSMUSG00000038859,BAIAP2L1,BAI1-associated protein 2-like 1,nucleus|cytoplasm|cytosol|cytoskeleton|plasma membrane|actin cytoskeleton|extracellular vesicular exosome|,signal transduction|response to bacterium|positive regulation of actin filament polymerization|regulation of actin cytoskeleton organization|filopodium assembly|positive regulation of actin cytoskeleton reorganization|,actin binding|cytoskeletal adaptor activity|SH3 domain binding|proline-rich region binding|,10,0.2,1.44,10,-0.8,1.5,0.1,0.572,0.572,0.627,0,0,-2,0.9
ENSMUSG00000019278,DPEP1,dipeptidase 1 (renal),plasma membrane|membrane|anchored component of membrane|cell projection|apical part of cell|extracellular vesicular exosome|,proteolysis|antibiotic metabolic process|negative regulation of cell migration|cellular response to drug|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|homocysteine metabolic process|,peptidase activity|metalloexopeptidase activity|metallopeptidase activity|dipeptidyl-peptidase activity|zinc ion binding|hydrolase activity|dipeptidase activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|metal ion binding|metallodipeptidase activity|modified amino acid binding|,9,0.1,0.503,9,-0.3,1.1,0.1,0.568,0.568,0.629,0,0,-1.6,1.2
ENSMUSG00000042529,KCNJ12,"potassium inwardly-rectifying channel, subfamily J, member 12",plasma membrane|membrane|integral component of membrane|T-tubule|dendrite|intrinsic component of membrane|neuronal cell body|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homotetramerization|potassium ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|PDZ domain binding|,10,0.4,1.44,10,0,0,0.2,0.564,0.564,0.63,0,0,-0.7,1.9
ENSMUSG00000049858,SUOX,sulfite oxidase,mitochondrion|mitochondrial intermembrane space|cytosol|,response to nutrient|oxidation-reduction process|,sulfite oxidase activity|electron carrier activity|oxidoreductase activity|heme binding|molybdenum ion binding|molybdopterin cofactor binding|metal ion binding|,10,-0.2,0.284,10,0.2,0.692,0.1,0.558,0.558,0.631,0,0,-1.3,1.5
ENSMUSG00000035984,NME5,NME/NM23 family member 5,sperm flagellum|,response to reactive oxygen species|epithelial cilium movement|nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|multicellular organismal development|spermatogenesis|spermatid development|spermatid development|ventricular system development|cell differentiation|cilium assembly|spermatid differentiation|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,molecular_function|nucleoside diphosphate kinase activity|ATP binding|,10,0.1,0.151,9,-0.8,1.63,-0.7,0.556,-0.556,0.632,0,0,-2,1
ENSMUSG00000002769,GNMT,glycine N-methyltransferase,cytoplasm|,glycogen metabolic process|regulation of gluconeogenesis|methionine metabolic process|one-carbon metabolic process|methylation|S-adenosylmethionine metabolic process|S-adenosylmethionine metabolic process|protein homotetramerization|protein homotetramerization|,folic acid binding|methyltransferase activity|glycine binding|glycine binding|transferase activity|glycine N-methyltransferase activity|glycine N-methyltransferase activity|,9,1.3,2.79,9,-0.4,1.36,1.2,0.551,0.551,0.633,0,0,-0.8,2
ENSMUSG00000035683,MELK,maternal embryonic leucine zipper kinase,cytoplasm|plasma membrane|cell cortex|membrane|membrane|,protein phosphorylation|apoptotic process|cell cycle|cell proliferation|intrinsic apoptotic signaling pathway in response to oxidative stress|phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of apoptotic process|protein autophosphorylation|neural precursor cell proliferation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|non-membrane spanning protein tyrosine kinase activity|calcium ion binding|protein binding|ATP binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,-0.2,0.273,9,0.2,0.879,-0.2,0.544,-0.544,0.635,0,0,-1.6,1.2
ENSMUSG00000027797,DCLK1,doublecortin-like kinase 1,None,neuron migration|protein phosphorylation|multicellular organismal development|nervous system development|axonogenesis|brain development|phosphorylation|central nervous system projection neuron axonogenesis|cell differentiation|forebrain development|intracellular signal transduction|axon extension|dendrite morphogenesis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.312,10,-0.1,0.295,-0.1,0.541,-0.541,0.636,0,0,-1.1,1.8
ENSMUSG00000002660,CLPP,caseinolytic mitochondrial matrix peptidase proteolytic subunit,mitochondrion|mitochondrion|mitochondrial matrix|endopeptidase Clp complex|,proteolysis|misfolded or incompletely synthesized protein catabolic process|protein homooligomerization|proteolysis involved in cellular protein catabolic process|,serine-type endopeptidase activity|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|identical protein binding|,10,0.4,1.17,10,0.1,0.195,0.1,0.537,0.537,0.637,0,0,-1.7,1.2
ENSMUSG00000004591,PKN2,protein kinase N2,nucleus|nucleus|cytoplasm|cytoplasm|centrosome|cytoskeleton|membrane|lamellipodium|cell junction|midbody|cleavage furrow|cell projection|apical junction complex|apical junction complex|intermediate filament cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|cell cycle|cell adhesion|signal transduction|epithelial cell migration|phosphorylation|positive regulation of cytokinesis|apical junction assembly|apical junction assembly|positive regulation of mitotic cell cycle|cell division|regulation of cell motility|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|histone deacetylase binding|poly(A) RNA binding|",10,-0.3,0.909,10,-0.1,0.0231,-0.1,0.536,-0.536,0.637,0,0,-1.3,1.7
ENSMUSG00000021518,PTDSS1,phosphatidylserine synthase 1,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,lipid metabolic process|phosphatidylserine biosynthetic process|phospholipid biosynthetic process|,transferase activity|,5,0.1,0.171,6,0.4,0.772,0.3,0.535,0.535,0.638,0,0,-1.3,2
ENSMUSG00000052423,B4GALT3,"UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3",cytoplasm|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,carbohydrate metabolic process|biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity|N-acetyllactosamine synthase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,-0.2,1.41,-0.2,0.534,-0.534,0.638,0,0,-1.7,1
ENSMUSG00000033618,MAP3K13,mitogen-activated protein kinase kinase kinase 13,cytoplasm|IkappaB kinase complex|membrane|,activation of MAPKK activity|protein phosphorylation|JNK cascade|phosphorylation|protein autophosphorylation|positive regulation of NF-kappaB transcription factor activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|protein homodimerization activity|metal ion binding|",10,0.5,1.68,10,-0.3,0.811,0.1,0.531,0.531,0.639,0,0,-1,1.8
ENSMUSG00000044951,MYLK4,"myosin light chain kinase family, member 4",extracellular vesicular exosome|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.662,10,0.1,0.0692,0.1,0.531,0.531,0.639,0,0,-1.3,1.5
ENSMUSG00000026094,STK17B,serine/threonine kinase 17b (apoptosis-inducing),nucleus|plasma membrane|actin cytoskeleton|membrane|,protein phosphorylation|apoptotic process|programmed cell death|phosphorylation|intracellular signal transduction|protein autophosphorylation|positive regulation of fibroblast apoptotic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.4,2.74,10,0.3,0.432,1.4,0.531,0.531,0.639,0,0,-0.6,3
ENSMUSG00000028894,INPP5B,inositol polyphosphate-5-phosphatase B,intracellular|cytoplasm|endosome|Golgi apparatus|cytosol|cytosol|microtubule cytoskeleton|membrane|integral component of membrane|cytoplasmic vesicle|,in utero embryonic development|signal transduction|spermatogenesis|dephosphorylation|sperm motility|phosphatidylinositol dephosphorylation|phosphatidylinositol dephosphorylation|regulation of protein processing|,"phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|inositol-polyphosphate 5-phosphatase activity|hydrolase activity|metal ion binding|inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|",10,0.5,1.01,10,-0.5,0.365,0.1,0.531,0.531,0.639,0,0,-1.4,1.5
ENSMUSG00000033610,PANK1,pantothenate kinase 1,nucleus|cytosol|clathrin coat|recycling endosome|cell periphery|,coenzyme A biosynthetic process|coenzyme A biosynthetic process|coenzyme A biosynthetic process|phosphorylation|,nucleotide binding|pantothenate kinase activity|pantothenate kinase activity|ATP binding|kinase activity|transferase activity|,10,1,1.42,10,0,0,0.2,0.521,0.521,0.641,0,0,-0.4,2
ENSMUSG00000005514,POR,P450 (cytochrome) oxidoreductase,mitochondrion|endoplasmic reticulum|cytosol|membrane|intracellular membrane-bounded organelle|,regulation of growth plate cartilage chondrocyte proliferation|internal peptidyl-lysine acetylation|fatty acid oxidation|positive regulation of chondrocyte differentiation|positive regulation of monooxygenase activity|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|nitrate catabolic process|positive regulation of cholesterol biosynthetic process|positive regulation of smoothened signaling pathway|nitric oxide catabolic process|oxidation-reduction process|oxidation-reduction process|negative regulation of lipase activity|demethylation|positive regulation of steroid hormone biosynthetic process|regulation of cholesterol metabolic process|cellular organofluorine metabolic process|,"NADPH-hemoprotein reductase activity|NADPH-hemoprotein reductase activity|cytochrome-b5 reductase activity, acting on NAD(P)H|iron ion binding|nitric oxide dioxygenase activity|electron carrier activity|FMN binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen|hydrolase activity|enzyme binding|iron-cytochrome-c reductase activity|flavin adenine dinucleotide binding|NADP binding|",10,0,0,10,-0.5,1.9,-0.2,0.516,-0.516,0.643,0,0,-1.8,1
ENSMUSG00000034987,HRH2,histamine receptor H2,plasma membrane|membrane|integral component of membrane|,gastric acid secretion|histamine-induced gastric acid secretion|gastrin-induced gastric acid secretion|epithelial cell morphogenesis|signal transduction|G-protein coupled receptor signaling pathway|memory|visual learning|positive regulation of vasoconstriction|regulation of synaptic plasticity|digestive tract development|gland development|,signal transducer activity|G-protein coupled receptor activity|histamine receptor activity|,10,-0.2,0.463,10,-0.1,0.157,-0.1,0.513,-0.513,0.644,0,0,-1.3,1.6
ENSMUSG00000023403,STK31,serine threonine kinase 31,acrosomal vesicle|,protein phosphorylation|phosphorylation|,"nucleotide binding|nucleic acid binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|hydrolase activity, acting on ester bonds|",10,0.7,2.94,10,0,0,0.2,0.506,0.506,0.646,0,0,-0.5,2
ENSMUSG00000042817,FLT3,FMS-like tyrosine kinase 3,nucleus|cytoplasm|endoplasmic reticulum|cytosol|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|protein complex|,leukocyte homeostasis|leukocyte homeostasis|positive regulation of protein phosphorylation|myeloid progenitor cell differentiation|myeloid progenitor cell differentiation|myeloid progenitor cell differentiation|lymphoid progenitor cell differentiation|pro-B cell differentiation|pro-B cell differentiation|pro-T cell differentiation|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|negative regulation of cell proliferation|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|hemopoiesis|lymphocyte differentiation|B cell differentiation|B cell differentiation|common myeloid progenitor cell proliferation|common myeloid progenitor cell proliferation|negative regulation of B cell differentiation|lymphocyte proliferation|lymphocyte proliferation|protein autophosphorylation|cellular response to cytokine stimulus|cellular response to cytokine stimulus|dendritic cell differentiation|dendritic cell differentiation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|cytokine receptor activity|cytokine receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein complex binding|glucocorticoid receptor binding|phosphatidylinositol 3-kinase binding|",10,-0.2,0.878,10,0.3,0.544,-0.2,0.5,-0.5,0.648,0,0,-1.6,1.2
ENSMUSG00000026622,NEK2,NIMA (never in mitosis gene a)-related expressed kinase 2,"chromosome, centromeric region|kinetochore|kinetochore|condensed nuclear chromosome|spindle pole|nucleus|chromosome|cytoplasm|centrosome|cytoskeleton|microtubule|midbody|protein complex|intercellular bridge|",mitotic sister chromatid segregation|blastocyst development|protein phosphorylation|protein phosphorylation|cell cycle|chromosome segregation|chromosome segregation|mitotic nuclear division|meiotic nuclear division|phosphorylation|negative regulation of DNA binding|protein autophosphorylation|centrosome separation|cell division|regulation of attachment of spindle microtubules to kinetochore|spindle assembly involved in mitosis|negative regulation of centriole-centriole cohesion|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|metal ion binding|",10,-0.9,2.48,10,0.3,1.2,-0.4,0.495,-0.495,0.649,0,0,-2,0.7
ENSMUSG00000030088,ALDH1L1,"aldehyde dehydrogenase 1 family, member L1",cytoplasm|mitochondrion|protein complex|extracellular vesicular exosome|,one-carbon metabolic process|metabolic process|biosynthetic process|10-formyltetrahydrofolate catabolic process|oxidation-reduction process|,"catalytic activity|aldehyde dehydrogenase [NAD(P)+] activity|protein binding|methyltransferase activity|formyltetrahydrofolate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|hydroxymethyl-, formyl- and related transferase activity|protein complex binding|aldehyde dehydrogenase (NADP+) activity|",10,-0.1,0.0933,10,-0.6,0.938,-0.2,0.494,-0.494,0.649,0,0,-2,0.6
ENSMUSG00000008540,MGST1,microsomal glutathione S-transferase 1,nucleus|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|peroxisomal membrane|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|apical part of cell|,glutathione metabolic process|response to organonitrogen compound|response to lipopolysaccharide|response to drug|oxidation-reduction process|protein homotrimerization|cellular response to lipid hydroperoxide|,glutathione transferase activity|glutathione transferase activity|glutathione peroxidase activity|transferase activity|identical protein binding|protein homodimerization activity|glutathione binding|,10,-0.1,0.202,10,-0.1,0.333,-0.1,0.49,-0.49,0.651,0,0,-1.8,0.9
ENSMUSG00000030236,SLCO1B2,"solute carrier organic anion transporter family, member 1b2",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,transport|ion transport|drug transmembrane transport|oligopeptide transport|lipid transport|organic anion transport|bile acid and bile salt transport|drug transport|ion transmembrane transport|,transporter activity|organic anion transmembrane transporter activity|bile acid transmembrane transporter activity|oligopeptide transporter activity|drug transmembrane transporter activity|,10,0.4,2.82,10,0,0,0.4,0.482,0.482,0.653,0,0,-1.1,1.6
ENSMUSG00000031918,MTMR2,myotubularin related protein 2,nucleus|cytoplasm|cytoplasm|endosome|vacuolar membrane|cytosol|synaptic vesicle|membrane|axon|dendrite|dendritic spine|synaptic membrane|neuronal postsynaptic density|,negative regulation of receptor internalization|dephosphorylation|dephosphorylation|negative regulation of myelination|myelin assembly|myelin assembly|negative regulation of endocytosis|phosphatidylinositol metabolic process|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|neuron development|protein tetramerization|negative regulation of excitatory postsynaptic membrane potential|dendritic spine maintenance|positive regulation of early endosome to late endosome transport|negative regulation of receptor catabolic process|,"protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|protein homodimerization activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol phosphate phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,1.2,3.3,10,-0.2,1.46,-0.2,0.479,-0.479,0.654,0,0,-0.6,2
ENSMUSG00000026822,LCN2,lipocalin 2,extracellular region|extracellular space|cytosol|extracellular vesicular exosome|,immune system process|transport|ion transport|apoptotic process|response to virus|response to herbicide|positive regulation of gene expression|siderophore transport|siderophore transport|positive regulation of cell projection organization|response to drug|innate immune response|iron ion homeostasis|protein homotrimerization|cellular response to hydrogen peroxide|extrinsic apoptotic signaling pathway in absence of ligand|,protease binding|transporter activity|iron ion binding|protein binding|small molecule binding|protein homodimerization activity|,10,0,0,10,-0.8,1.62,-0.1,0.477,-0.477,0.654,0,0,-2,0.7
ENSMUSG00000003269,CYTH2,cytohesin 2,cytoplasm|plasma membrane|plasma membrane|membrane|,regulation of cell adhesion|regulation of cell adhesion|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,"guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|protein binding|lipid binding|inositol 1,4,5 trisphosphate binding|",10,0.2,0.591,10,-0.9,2.86,-0.2,0.476,-0.476,0.655,0,0,-2,0.9
ENSMUSG00000008435,RDH13,retinol dehydrogenase 13 (all-trans and 9-cis),mitochondrion|,metabolic process|response to high light intensity|retina layer formation|eye photoreceptor cell development|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.1,0.204,10,0.4,0.618,0.2,0.469,0.469,0.657,0,0,-0.8,1.9
ENSMUSG00000022263,TRIO,triple functional domain (PTPRF interacting),cytoplasm|,protein phosphorylation|phosphorylation|regulation of Rho protein signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|",10,-0.1,0.204,10,-0.1,0.306,-0.1,0.467,-0.467,0.658,0,0,-1.8,0.9
ENSMUSG00000091091,KCNMB3,"potassium large conductance calcium-activated channel, subfamily M, beta member 3",integral component of plasma membrane|voltage-gated potassium channel complex|,action potential|detection of calcium ion|potassium ion transport|neuronal action potential|potassium ion transmembrane transport|,calcium-activated potassium channel activity|,9,0.4,1.98,9,0,0,0.1,0.467,0.467,0.658,0,0,-1.2,1.7
ENSMUSG00000042064,MYO3B,myosin IIIB,photoreceptor outer segment|photoreceptor inner segment|cytoplasm|cytoskeleton|myosin complex|stereocilium bundle tip|filopodium tip|,protein phosphorylation|visual perception|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|protein autophosphorylation|response to stimulus|positive regulation of filopodium assembly|,"microfilament motor activity|nucleotide binding|motor activity|actin binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.6,1.17,10,-0.1,0.0359,-0.2,0.465,-0.465,0.658,0,0,-2,0.8
ENSMUSG00000046949,NQO2,"NAD(P)H dehydrogenase, quinone 2",nucleus|cytoplasm|extracellular vesicular exosome|,oxidation-reduction process|,dihydronicotinamide riboside quinone reductase activity|oxidoreductase activity|metal ion binding|,9,-0.9,1.14,10,-0.1,0.525,-0.1,0.464,-0.464,0.659,0,0,-2,0.6
ENSMUSG00000028525,PDE4B,"phosphodiesterase 4B, cAMP specific",nucleus|cytoplasm|cytosol|voltage-gated calcium channel complex|Z disc|perinuclear region of cytoplasm|cell periphery|,neutrophil homeostasis|cAMP catabolic process|cAMP catabolic process|neutrophil chemotaxis|positive regulation of interferon-gamma production|positive regulation of interleukin-2 production|cellular response to drug|T cell receptor signaling pathway|leukocyte migration|cellular response to lipopolysaccharide|cellular response to epinephrine stimulus|regulation of cardiac muscle cell contraction|regulation of high voltage-gated calcium channel activity|negative regulation of relaxation of cardiac muscle|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|hydrolase activity|cAMP binding|ion channel binding|metal ion binding|",9,-0.1,0.0236,9,-0.2,0.627,-0.1,0.462,-0.462,0.659,0,0,-1.9,1
ENSMUSG00000032401,LCTL,lactase-like,endoplasmic reticulum|membrane|integral component of membrane|,carbohydrate metabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|",10,-0.5,1.86,10,0,0,-0.2,0.458,-0.458,0.66,0,0,-2,0.5
ENSMUSG00000057530,ECE1,endothelin converting enzyme 1,lysosomal membrane|endosome|early endosome|Golgi apparatus|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|secretory granule|cytoplasmic vesicle|vesicle|Weibel-Palade body|perinuclear region of cytoplasm|extracellular vesicular exosome|,response to hypoxia|positive regulation of receptor recycling|proteolysis|proteolysis|apoptotic process|heart development|regulation of blood pressure|positive regulation of cardiac muscle hypertrophy|substance P catabolic process|bradykinin catabolic process|calcitonin catabolic process|protein processing|peptide hormone processing|peptide hormone processing|positive regulation of cAMP biosynthetic process|endothelin maturation|regulation of vasodilation|hormone catabolic process|embryonic digit morphogenesis|ear development|positive regulation of G-protein coupled receptor protein signaling pathway|pharyngeal system development|regulation of ERK1 and ERK2 cascade|,endopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|protein homodimerization activity|metal ion binding|,10,0.2,0.528,10,0.1,0.0983,0.2,0.457,0.457,0.661,0,0,-0.8,1.9
ENSMUSG00000035032,NEK11,NIMA (never in mitosis gene a)-related expressed kinase 11,nucleus|,protein phosphorylation|cell cycle|phosphorylation|G2 DNA damage checkpoint|intra-S DNA damage checkpoint|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.2,0.289,10,-0.2,0.764,-0.1,0.456,-0.456,0.661,0,0,-1.5,1.2
ENSMUSG00000057933,GSTA2,"glutathione S-transferase, alpha 2 (Yc2)",None,metabolic process|,glutathione transferase activity|transferase activity|,10,-0.1,0.361,10,0.4,1.14,0.3,0.452,0.452,0.662,0,0,-0.7,1.9
ENSMUSG00000025386,PDE6G,"phosphodiesterase 6G, cGMP-specific, rod, gamma",None,activation of MAPK activity|visual perception|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|response to stimulus|,"3',5'-cyclic-nucleotide phosphodiesterase activity|protein binding|hydrolase activity|spectrin binding|cGMP binding|3',5'-cyclic-GMP phosphodiesterase activity|",10,-0.2,0.488,10,0.1,0.0821,0.1,0.449,0.449,0.663,0,0,-1.5,1.3
ENSMUSG00000027859,NGF,nerve growth factor,extracellular region|extracellular space|,peripheral nervous system development|memory|positive regulation of cell proliferation|adult locomotory behavior|extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of gene expression|positive regulation of neuron projection development|positive regulation of neuron projection development|positive regulation of neuron maturation|positive regulation of neuron maturation|sensory perception of pain|sensory perception of pain|positive regulation of cell growth|neuron projection development|positive regulation of protein autophosphorylation|intracellular signal transduction|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of axon extension|regulation of neurotransmitter secretion|neuron projection morphogenesis|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of neurotrophin TRK receptor signaling pathway|neuron apoptotic process|extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of stem cell proliferation|negative regulation of type B pancreatic cell apoptotic process|,receptor signaling protein activity|receptor binding|nerve growth factor receptor binding|growth factor activity|,9,0.1,0.207,9,0.6,1.01,0.6,0.447,0.447,0.664,0,0,-0.9,1.9
ENSMUSG00000041698,SLCO1A1,"solute carrier organic anion transporter family, member 1a1",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,transport|ion transport|organic anion transport|ion transmembrane transport|,transporter activity|organic anion transmembrane transporter activity|,10,-0.2,0.659,10,0,0,-0.2,0.446,-0.446,0.664,0,0,-1.8,0.8
ENSMUSG00000019989,ENPP3,ectonucleotide pyrophosphatase/phosphodiesterase 3,extracellular region|membrane|integral component of membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,phosphate-containing compound metabolic process|immune response|metabolic process|nucleoside triphosphate catabolic process|,nucleic acid binding|catalytic activity|phosphodiesterase I activity|nucleotide diphosphatase activity|scavenger receptor activity|hydrolase activity|polysaccharide binding|NADH pyrophosphatase activity|metal ion binding|nucleoside-triphosphate diphosphatase activity|,10,-0.4,2.56,10,0,0,-0.3,0.446,-0.446,0.664,0,0,-1.3,1.6
ENSMUSG00000001985,GRIK3,"glutamate receptor, ionotropic, kainate 3",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|axon|dendrite|dendrite|dendrite cytoplasm|kainate selective glutamate receptor complex|presynaptic membrane|terminal bouton|perikaryon|synapse|postsynaptic membrane|,"transport|ion transport|signal transduction|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|ion transmembrane transport|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|regulation of membrane potential|negative regulation of synaptic transmission, glutamatergic|",adenylate cyclase inhibiting G-protein coupled glutamate receptor activity|receptor activity|ionotropic glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|glutamate receptor activity|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|,10,0.5,0.305,10,-0.2,0.714,-0.1,0.443,-0.443,0.666,0,0,-1.1,1.7
ENSMUSG00000033703,FUK,fucokinase,cellular_component|,biological_process|phosphorylation|,nucleotide binding|molecular_function|ATP binding|kinase activity|transferase activity|fucokinase activity|,10,-0.2,0.651,10,0.2,0.435,-0.1,0.438,-0.438,0.667,0,0,-1.4,1.5
ENSMUSG00000004113,CACNA1B,"calcium channel, voltage-dependent, N type, alpha 1B subunit",cell|plasma membrane|voltage-gated calcium channel complex|membrane|integral component of membrane|dendrite|neuron projection|neuronal cell body|neuronal cell body|dendritic shaft|protein complex|axon terminus|,positive regulation of neurotransmitter secretion|transport|ion transport|calcium ion transport|calcium ion transport|neurotransmitter secretion|locomotory behavior|regulation of heart contraction|regulation of blood pressure|response to organic cyclic compound|sensory perception of pain|response to testosterone|regulation of ion transmembrane transport|response to pain|regulation of calcium ion transport|transmembrane transport|calcium ion import|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,nucleotide binding|ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|calcium ion binding|protein binding|ATP binding|protein C-terminus binding|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|metal ion binding|,10,0.2,0.911,10,-0.1,0.29,0.2,0.437,0.437,0.668,0,0,-1.1,1.6
ENSMUSG00000026253,CHRNG,"cholinergic receptor, nicotinic, gamma polypeptide",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,skeletal muscle contraction|transport|ion transport|cation transport|cation transport|ion transmembrane transport|ion transmembrane transport|regulation of membrane potential|,acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|ligand-gated ion channel activity|,10,-0.2,0.547,10,0.6,0.81,-0.2,0.436,-0.436,0.668,0,0,-1,1.9
ENSMUSG00000040390,MAP3K10,mitogen-activated protein kinase kinase kinase 10,cytoplasm|,"protein phosphorylation|protein phosphorylation|smoothened signaling pathway|cell death|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|positive regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of JUN kinase activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of JNK cascade|","nucleotide binding|transcription corepressor activity|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|bHLH transcription factor binding|",10,0.3,0.551,10,0,0,0.3,0.434,0.434,0.669,0,0,-0.9,1.8
ENSMUSG00000035941,IBTK,inhibitor of Bruton agammaglobulinemia tyrosine kinase,nucleus|cytoplasm|membrane|,negative regulation of protein phosphorylation|release of sequestered calcium ion into cytosol|negative regulation of protein tyrosine kinase activity|,protein kinase binding|protein tyrosine kinase inhibitor activity|,10,-0.4,1.38,10,0,0,-0.2,0.424,-0.424,0.672,0,0,-1.9,0.7
ENSMUSG00000042133,PPIG,peptidyl-prolyl isomerase G (cyclophilin G),nucleus|cytoplasm|nuclear matrix|,protein peptidyl-prolyl isomerization|protein folding|,peptidyl-prolyl cis-trans isomerase activity|isomerase activity|poly(A) RNA binding|,10,0.1,0.0949,10,0.5,0.963,0.1,0.421,0.421,0.673,0,0,-1.4,1.7
ENSMUSG00000024650,SLC22A6,"solute carrier family 22 (organic anion transporter), member 6",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|integral component of plasma membrane|caveola|membrane|integral component of membrane|basolateral plasma membrane|protein complex|extracellular vesicular exosome|,anion transport|organic anion transport|organic anion transport|organic anion transport|organic anion transport|organic anion transport|alpha-ketoglutarate transport|ion transmembrane transport|sodium-independent organic anion transport|protein homooligomerization|transmembrane transport|renal tubular secretion|renal tubular secretion|,inorganic anion exchanger activity|organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|ion transmembrane transporter activity|anion:anion antiporter activity|sodium-independent organic anion transmembrane transporter activity|transmembrane transporter activity|chloride ion binding|protein homodimerization activity|,9,-0.2,0.761,10,0,0,-0.1,0.416,-0.416,0.675,0,0,-1.7,1.2
ENSMUSG00000050350,GPR18,G protein-coupled receptor 18,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0.3,0.936,10,0,0,0.2,0.402,0.402,0.68,0,0,-0.9,1.8
ENSMUSG00000024781,LIPA,lysosomal acid lipase A,lysosome|extracellular vesicular exosome|,cell morphogenesis|cytokine production|lipid metabolic process|fatty acid metabolic process|inflammatory response|cell proliferation|lipid catabolic process|sterol metabolic process|lung development|tissue remodeling|homeostasis of number of cells within a tissue|,"sterol esterase activity|lipase activity|hydrolase activity|hydrolase activity, acting on ester bonds|",10,0.1,0.0219,10,0.3,0.941,0.1,0.401,0.401,0.68,0,0,-1,1.8
ENSMUSG00000011148,ADSSL1,adenylosuccinate synthetase like 1,cytoplasm|cytoplasm|membrane|,purine nucleotide metabolic process|purine nucleotide biosynthetic process|AMP biosynthetic process|GTP catabolic process|aspartate metabolic process|purine ribonucleoside monophosphate biosynthetic process|IMP metabolic process|,nucleotide binding|GTPase activity|adenylosuccinate synthase activity|adenylosuccinate synthase activity|protein binding|GTP binding|ligase activity|protein homodimerization activity|metal ion binding|actin filament binding|,10,-0.1,0.375,10,-0.1,0.0564,-0.1,0.395,-0.395,0.682,0,0,-1.6,1.3
ENSMUSG00000039450,DCXR,dicarbonyl L-xylulose reductase,nucleus|cytoplasmic microtubule|plasma membrane|microvillus|brush border|membrane|extracellular vesicular exosome|,carbohydrate metabolic process|xylulose metabolic process|xylulose metabolic process|glucose metabolic process|glucose metabolic process|NADP metabolic process|metabolic process|D-xylose metabolic process|protein homotetramerization|protein homotetramerization|oxidation-reduction process|oxidation-reduction process|,"protein binding|oxidoreductase activity|oxidoreductase activity, acting on CH-OH group of donors|oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor|L-xylulose reductase (NADP+) activity|L-xylulose reductase (NADP+) activity|",10,-0.2,0.616,9,0,0,-0.1,0.388,-0.388,0.684,0,0,-1.3,1.6
ENSMUSG00000068206,PICK1,protein interacting with C kinase 1,intracellular|cytoplasm|cytoplasm|mitochondrion|Golgi apparatus|cytoskeleton|plasma membrane|postsynaptic density|membrane|cell junction|dendrite|presynaptic membrane|neuron projection|protein complex|synapse|synapse|postsynaptic membrane|perinuclear region of cytoplasm|perinuclear region of cytoplasm|neuronal postsynaptic density|,positive regulation of receptor internalization|ATP catabolic process|protein phosphorylation|protein targeting|protein kinase C-activating G-protein coupled receptor signaling pathway|multicellular organismal development|monoamine transport|phosphorylation|glial cell development|negative regulation of Arp2/3 complex-mediated actin nucleation|intracellular signal transduction|cellular response to decreased oxygen levels|cellular response to glucose starvation|receptor clustering|receptor clustering|regulation of synapse structure and activity|protein homooligomerization|long term synaptic depression|dendritic spine organization|dendritic spine maintenance|,actin binding|protein kinase C binding|protein kinase C binding|receptor binding|receptor binding|protein binding|protein C-terminus binding|kinase activity|transferase activity|ATPase activity|enzyme binding|protein domain specific binding|identical protein binding|metal ion binding|actin filament binding|Arp2/3 complex binding|,10,0,0,10,-1.1,3.1,-1.1,0.381,-0.381,0.687,0,0,-2,0.5
ENSMUSG00000029311,HSD17B11,hydroxysteroid (17-beta) dehydrogenase 11,extracellular region|cytoplasm|lipid particle|,lipid metabolic process|steroid biosynthetic process|androgen catabolic process|metabolic process|oxidation-reduction process|,estradiol 17-beta-dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|,10,1,0.954,9,-0.2,0.101,-0.2,0.375,-0.375,0.689,0,0,-1.2,2
ENSMUSG00000039236,ISG20,interferon-stimulated protein,nucleus|nucleolus|cytoplasm|Cajal body|PML body|,"DNA catabolic process, exonucleolytic|immune system process|rRNA processing|RNA catabolic process|response to virus|negative regulation of viral genome replication|innate immune response|defense response to virus|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|nucleic acid binding|RNA binding|nuclease activity|exonuclease activity|single-stranded DNA 3'-5' exodeoxyribonuclease activity|exoribonuclease II activity|hydrolase activity|U1 snRNA binding|U2 snRNA binding|U3 snoRNA binding|metal ion binding|,10,-0.1,0.206,10,-0.1,0.199,-0.1,0.37,-0.37,0.691,0,0,-1.8,1
ENSMUSG00000079227,CCR5,chemokine (C-C motif) receptor 5,cytoplasm|endosome|plasma membrane|external side of plasma membrane|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|,calcium ion transport|chemotaxis|defense response|inflammatory response|immune response|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|cell-cell signaling|positive regulation of gene expression|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|calcium-mediated signaling|positive regulation of cell-cell adhesion|negative regulation of cell migration|negative regulation of axon extension|positive regulation of fever generation|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of neuron differentiation|positive regulation of interleukin-1 beta secretion|positive regulation of inflammatory response|positive regulation of apoptotic process by virus|chemokine-mediated signaling pathway|chemokine-mediated signaling pathway|response to cholesterol|neuron death|positive regulation of cell migration involved in sprouting angiogenesis|negative regulation of macrophage apoptotic process|negative regulation of neural precursor cell proliferation|,glycoprotein binding|actin binding|signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|C-C chemokine receptor activity|C-C chemokine receptor activity|protein kinase binding|C-C chemokine binding|C-C chemokine binding|chemokine (C-C motif) ligand 5 binding|,10,0.2,0.864,10,0,0,0.1,0.37,0.37,0.691,0,0,-1.2,1.7
ENSMUSG00000061751,KALRN,"kalirin, RhoGEF kinase",cytoplasm|cytoskeleton|neuron projection|neuronal cell body|perinuclear region of cytoplasm|extracellular vesicular exosome|,protein phosphorylation|nervous system development|axonogenesis|phosphorylation|regulation of Rho protein signal transduction|intracellular signal transduction|regulation of dendrite development|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|metal ion binding|",10,-0.1,0.0583,10,-0.2,0.392,-0.1,0.366,-0.366,0.692,0,0,-1.6,1.2
ENSMUSG00000024952,RPS6KA4,"ribosomal protein S6 kinase, polypeptide 4",nucleus|cytoplasm|,"regulation of transcription, DNA-templated|protein phosphorylation|response to stress|inflammatory response|phosphorylation|positive regulation of histone phosphorylation|positive regulation of histone acetylation|intracellular signal transduction|histone H3-S10 phosphorylation|histone H3-S28 phosphorylation|positive regulation of transcription from RNA polymerase II promoter|interleukin-1-mediated signaling pathway|","nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase p38 binding|",10,-0.3,2.25,10,0.1,0.0733,-0.2,0.365,-0.365,0.693,0,0,-1.7,1
ENSMUSG00000033985,TESK2,testis-specific kinase 2,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|actin cytoskeleton organization|focal adhesion assembly|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.7,1.94,10,-0.4,1.58,-0.2,0.363,-0.363,0.693,0,0,-1.1,1.8
ENSMUSG00000056755,GRM7,"glutamate receptor, metabotropic 7",rough endoplasmic reticulum|Golgi apparatus|plasma membrane|integral component of plasma membrane|cell cortex|cell surface|membrane|integral component of membrane|axon|dendrite|asymmetric synapse|presynaptic membrane|presynaptic membrane|neuronal cell body|terminal bouton|dendritic shaft|protein complex|receptor complex|axon terminus|synapse|postsynaptic membrane|presynaptic active zone|presynaptic active zone membrane|,"conditioned taste aversion|behavioral fear response|signal transduction|G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|synaptic transmission|synaptic transmission|sensory perception of sound|sensory perception of smell|memory|short-term memory|associative learning|negative regulation of glutamate secretion|transmission of nerve impulse|adult behavior|negative regulation of cAMP biosynthetic process|regulation of cyclase activity|multicellular organismal response to stress|regulation of ion transmembrane transport|neurological system process|response to stimulus|regulation of synaptic transmission, glutamatergic|calcium ion transmembrane transport|regulation of neuron death|",adenylate cyclase inhibiting G-protein coupled glutamate receptor activity|group III metabotropic glutamate receptor activity|group III metabotropic glutamate receptor activity|group III metabotropic glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|voltage-gated calcium channel activity|calcium channel regulator activity|calcium ion binding|calmodulin binding|glutamate receptor activity|adenylate cyclase inhibitor activity|glutamate binding|PDZ domain binding|PDZ domain binding|protein homodimerization activity|calcium-dependent protein binding|serine binding|,10,0,0,10,0.4,1.08,0.1,0.363,0.363,0.693,0,0,-1,1.8
ENSMUSG00000020890,GUCY2E,guanylate cyclase 2e,plasma membrane|membrane|integral component of membrane|,cGMP biosynthetic process|protein phosphorylation|visual perception|cyclic nucleotide biosynthetic process|intracellular signal transduction|response to stimulus|,"nucleotide binding|guanylate cyclase activity|protein kinase activity|ATP binding|GTP binding|transferase activity, transferring phosphorus-containing groups|lyase activity|phosphorus-oxygen lyase activity|identical protein binding|",10,0,0,10,0.5,1.43,0.1,0.363,0.363,0.693,0,0,-1.5,1.6
ENSMUSG00000019139,ISYNA1,myo-inositol 1-phosphate synthase A1,cellular_component|cytoplasm|,inositol biosynthetic process|lipid metabolic process|biological_process|phospholipid biosynthetic process|,molecular_function|inositol-3-phosphate synthase activity|isomerase activity|,10,0,0,10,-0.1,0.429,-0.1,0.358,-0.358,0.695,0,0,-1.6,1.3
ENSMUSG00000024386,PROC,protein C,extracellular region|extracellular space|,proteolysis|blood coagulation|hemostasis|negative regulation of blood coagulation|negative regulation of apoptotic process|negative regulation of apoptotic process|,catalytic activity|serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.3,0.698,10,0,0,-0.2,0.357,-0.357,0.696,0,0,-1.8,0.9
ENSMUSG00000041261,CAR8,carbonic anhydrase 8,cytoplasm|,one-carbon metabolic process|phosphatidylinositol-mediated signaling|,carbonate dehydratase activity|protein binding|zinc ion binding|metal ion binding|,10,0,0,10,-0.2,1,-0.1,0.355,-0.355,0.696,0,0,-0.8,1.9
ENSMUSG00000037346,HRH4,histamine receptor H4,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,inflammatory response|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|regulation of MAPK cascade|,signal transducer activity|G-protein coupled receptor activity|histamine receptor activity|histamine receptor activity|,9,-0.1,0.233,10,-0.1,0.157,-0.1,0.355,-0.355,0.696,0,0,-1.8,1.1
ENSMUSG00000022225,CMA1,"chymase 1, mast cell",extracellular region|intracellular|extracellular matrix|,proteolysis|positive regulation of angiogenesis|interleukin-1 beta biosynthetic process|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|peptide binding|,10,0.9,0.924,10,-0.1,0.0599,-0.1,0.354,-0.354,0.697,0,0,-1.1,1.9
ENSMUSG00000074207,ADH1,alcohol dehydrogenase 1 (class I),intracellular|cytoplasm|mitochondrion|cytosol|,retinoid metabolic process|ethanol catabolic process|ethanol catabolic process|ethanol oxidation|response to retinoic acid|response to testosterone|retinol metabolic process|retinol metabolic process|retinoic acid metabolic process|retinoic acid metabolic process|acetaldehyde biosynthetic process|behavioral response to ethanol|response to steroid hormone|oxidation-reduction process|,alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase (NAD) activity|retinol dehydrogenase activity|drug binding|zinc ion binding|oxidoreductase activity|ethanol binding|protein homodimerization activity|metal ion binding|NAD binding|,10,-0.2,0.45,10,0,0,-0.2,0.347,-0.347,0.699,0,0,-1.9,0.8
ENSMUSG00000060166,ZDHHC8,"zinc finger, DHHC domain containing 8",mitochondrion|Golgi apparatus|membrane|integral component of membrane|cytoplasmic vesicle|perinuclear region of cytoplasm|,locomotory behavior|protein palmitoylation|,"protein binding|zinc ion binding|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,1.3,1.68,10,0,0,-0.1,0.346,-0.346,0.699,0,0,-1,2
ENSMUSG00000028766,ALPL,"alkaline phosphatase, liver/bone/kidney",extracellular space|plasma membrane|plasma membrane|membrane|extracellular matrix|anchored component of membrane|extracellular membrane-bounded organelle|extracellular vesicular exosome|,osteoblast differentiation|endochondral ossification|developmental process involved in reproduction|metabolic process|dephosphorylation|dephosphorylation|response to antibiotic|response to glucocorticoid|cellular response to organic cyclic compound|,catalytic activity|alkaline phosphatase activity|alkaline phosphatase activity|protein binding|pyrophosphatase activity|pyrophosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|,10,0.5,0.37,10,0.1,0.251,0.1,0.337,0.337,0.702,0,0,-0.9,1.8
ENSMUSG00000045551,FPR1,formyl peptide receptor 1,plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|N-formyl peptide receptor activity|N-formyl peptide receptor activity|RAGE receptor binding|,10,-0.2,0.711,10,0,0,-0.2,0.334,-0.334,0.703,0,0,-1.8,0.9
ENSMUSG00000027709,MCCC1,methylcrotonoyl-Coenzyme A carboxylase 1 (alpha),"3-methylcrotonyl-CoA carboxylase complex, mitochondrial|mitochondrion|mitochondrion|mitochondrial inner membrane|",metabolic process|,nucleotide binding|catalytic activity|biotin carboxylase activity|methylcrotonoyl-CoA carboxylase activity|methylcrotonoyl-CoA carboxylase activity|ATP binding|ligase activity|metal ion binding|,10,0.3,0.832,10,0,0,0.1,0.333,0.333,0.703,0,0,-0.9,1.9
ENSMUSG00000034573,PTPN13,"protein tyrosine phosphatase, non-receptor type 13",nucleus|nucleus|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|lamellipodium|cell projection|neuron projection|cell body|extracellular vesicular exosome|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,10,0.2,1.34,10,0,0,0.1,0.333,0.333,0.703,0,0,-1.4,1.5
ENSMUSG00000029054,GABRD,"gamma-aminobutyric acid (GABA) A receptor, subunit delta",plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|signal transduction|synaptic transmission|,GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|,10,-0.1,0.0502,10,0.2,0.866,0.1,0.331,0.331,0.704,0,0,-1.1,1.8
ENSMUSG00000026489,ADCK3,aarF domain containing kinase 3,mitochondrion|,ubiquinone biosynthetic process|biological_process|phosphorylation|,"nucleotide binding|molecular_function|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|ATP binding|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,0,0,10,-0.9,2.42,0.2,0.33,0.33,0.704,0,0,-2,1.2
ENSMUSG00000027130,SLC12A6,"solute carrier family 12, member 6",basolateral plasma membrane|axon|,ion transport|chloride transport|potassium ion import|rubidium ion transport|cellular hypotonic response|cellular hypotonic salinity response|chloride transmembrane transport|,protein binding|potassium ion transmembrane transporter activity|potassium:chloride symporter activity|protein kinase binding|rubidium ion transmembrane transporter activity|,4,-0.3,0.959,4,0.1,0.24,-0.2,0.325,-0.325,0.706,0,0,-1.9,1.5
ENSMUSG00000021868,PPIF,peptidylprolyl isomerase F (cyclophilin F),mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial permeability transition pore complex|mitochondrial matrix|,"protein peptidyl-prolyl isomerization|protein peptidyl-prolyl isomerization|response to ischemia|protein folding|apoptotic process|response to oxidative stress|apoptotic mitochondrial changes|regulation of proton-transporting ATPase activity, rotational mechanism|regulation of necrotic cell death|programmed cell death|negative regulation of ATPase activity|regulation of apoptotic process|negative regulation of apoptotic process|regulation of mitochondrial membrane permeability|regulation of mitochondrial membrane permeability|regulation of mitochondrial membrane permeability|necroptotic process|cellular response to hydrogen peroxide|cellular response to hydrogen peroxide|cellular response to arsenic-containing substance|cellular response to calcium ion|positive regulation of release of cytochrome c from mitochondria|negative regulation of release of cytochrome c from mitochondria|negative regulation of oxidative phosphorylation|regulation of mitochondrial membrane permeability involved in programmed necrotic cell death|regulation of mitochondrial membrane permeability involved in programmed necrotic cell death|negative regulation of oxidative phosphorylation uncoupler activity|negative regulation of intrinsic apoptotic signaling pathway|",peptidyl-prolyl cis-trans isomerase activity|peptidyl-prolyl cis-trans isomerase activity|protein binding|cyclosporin A binding|isomerase activity|peptide binding|,10,0.2,0.793,10,-0.2,1.41,0.1,0.325,0.325,0.706,0,0,-1.3,1.4
ENSMUSG00000021096,PPM1A,"protein phosphatase 1A, magnesium dependent, alpha isoform",nucleus|cytoplasm|cytosol|voltage-gated calcium channel complex|membrane|neuron projection|,"protein dephosphorylation|protein dephosphorylation|protein dephosphorylation|N-terminal protein myristoylation|negative regulation of SMAD protein complex assembly|Wnt signaling pathway|dephosphorylation|positive regulation of Wnt signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|peptidyl-threonine dephosphorylation|negative regulation of NF-kappaB import into nucleus|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of transcription, DNA-templated|",magnesium ion binding|catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|signal transducer activity|protein C-terminus binding|hydrolase activity|manganese ion binding|calmodulin-dependent protein phosphatase activity|metal ion binding|R-SMAD binding|,10,0.1,0.246,10,-0.2,0.301,-0.1,0.324,-0.324,0.706,0,0,-1.7,1.1
ENSMUSG00000028567,TXNDC12,thioredoxin domain containing 12 (endoplasmic reticulum),endoplasmic reticulum|,cell redox homeostasis|oxidation-reduction process|,oxidoreductase activity|protein-disulfide reductase (glutathione) activity|,10,0.2,1.61,10,0,0,0.1,0.324,0.324,0.706,0,0,-1,1.8
ENSMUSG00000006717,ACOT13,acyl-CoA thioesterase 13,nucleus|cytoplasm|mitochondrion|cytoskeleton|extracellular vesicular exosome|,metabolic process|protein homotetramerization|,"CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,1.2,1.93,10,0.2,0.735,-0.1,0.322,-0.322,0.707,0,0,-0.9,2
ENSMUSG00000013236,PTPRS,"protein tyrosine phosphatase, receptor type, S",membrane|integral component of membrane|extracellular vesicular exosome|,protein dephosphorylation|cell adhesion|dephosphorylation|spinal cord development|cerebellum development|hippocampus development|cerebral cortex development|corpus callosum development|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,9,0.2,1.11,9,0,0,0.1,0.319,0.319,0.708,0,0,-1.1,1.8
ENSMUSG00000022619,MAPK8IP2,mitogen-activated protein kinase 8 interacting protein 2,cytoplasm|cytoplasm|neuronal cell body|protein complex|neuronal postsynaptic density|,"MAPK cascade|behavioral fear response|JNK cascade|mating behavior|regulation of receptor activity|phosphorylation|positive regulation of stress-activated MAPK cascade|social behavior|positive regulation of protein kinase activity|regulation of JNK cascade|nonassociative learning|dendrite morphogenesis|regulation of synaptic transmission, glutamatergic|regulation of excitatory postsynaptic membrane potential|regulation of N-methyl-D-aspartate selective glutamate receptor activity|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|",protein binding|kinase activity|transferase activity|kinesin binding|protein kinase binding|protein kinase activator activity|protein complex binding|,10,-0.7,2.26,10,0.1,0.342,-0.6,0.312,-0.312,0.711,0,0,-2,0.7
ENSMUSG00000038168,LEPREL1,leprecan-like 1,basement membrane|endoplasmic reticulum|Golgi apparatus|,negative regulation of cell proliferation|peptidyl-proline hydroxylation|peptidyl-proline hydroxylation|collagen metabolic process|collagen metabolic process|oxidation-reduction process|,"iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|procollagen-proline 3-dioxygenase activity|procollagen-proline 3-dioxygenase activity|L-ascorbic acid binding|metal ion binding|dioxygenase activity|",10,0.1,0.0871,10,0.1,0.253,0.1,0.311,0.311,0.711,0,0,-1.1,1.7
ENSMUSG00000052151,PPAP2C,phosphatidic acid phosphatase type 2C,membrane|integral component of membrane|,dephosphorylation|,catalytic activity|phosphatidate phosphatase activity|hydrolase activity|,10,1.4,2.5,10,-0.1,0.668,-0.1,0.31,-0.31,0.711,0,0,-0.8,3
ENSMUSG00000033966,CDKL4,cyclin-dependent kinase-like 4,cellular_component|cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.1,3.56,10,-0.1,0.0511,0.3,0.309,0.309,0.712,0,0,-0.6,2
ENSMUSG00000028657,PPT1,palmitoyl-protein thioesterase 1,extracellular region|extracellular space|nucleus|lysosome|lysosome|lysosome|Golgi apparatus|synaptic vesicle|membrane|axon|axon|dendrite|neuron projection|neuronal cell body|neuronal cell body|membrane raft|synapse|extracellular vesicular exosome|,protein depalmitoylation|protein depalmitoylation|apoptotic DNA fragmentation|cellular protein modification process|receptor-mediated endocytosis|receptor-mediated endocytosis|pinocytosis|lysosome organization|lysosomal lumen acidification|neurotransmitter secretion|nervous system development|nervous system development|brain development|visual perception|grooming behavior|associative learning|adult locomotory behavior|protein transport|lipid catabolic process|negative regulation of cell growth|membrane raft organization|regulation of phospholipase A2 activity|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|cellular protein catabolic process|cellular macromolecule catabolic process|positive regulation of receptor-mediated endocytosis|positive regulation of pinocytosis|cofactor transport|cofactor metabolic process|,palmitoyl-(protein) hydrolase activity|palmitoyl-(protein) hydrolase activity|palmitoyl-(protein) hydrolase activity|palmitoyl-CoA hydrolase activity|hydrolase activity|,10,0.2,0.62,10,-0.2,1.01,-0.1,0.309,-0.309,0.712,0,0,-1.5,1.4
ENSMUSG00000004070,HMOX2,heme oxygenase (decycling) 2,endoplasmic reticulum|plasma membrane|membrane|intracellular membrane-bounded organelle|,response to hypoxia|heme oxidation|response to oxidative stress|oxidation-reduction process|,heme oxygenase (decyclizing) activity|oxidoreductase activity|metal ion binding|,10,-0.3,0.564,10,-0.1,0.0441,-0.1,0.307,-0.307,0.713,0,0,-1.6,1.4
ENSMUSG00000041534,RBP3,"retinol binding protein 3, interstitial",extracellular region|proteinaceous extracellular matrix|extracellular space|interphotoreceptor matrix|,proteolysis|transport|,serine-type peptidase activity|retinal binding|retinol binding|,10,0.2,1.58,10,-0.2,0.851,0.1,0.298,0.298,0.716,0,0,-1.4,1.4
ENSMUSG00000024404,RIOK3,RIO kinase 3,cellular_component|,protein phosphorylation|biological_process|phosphorylation|,"nucleotide binding|catalytic activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.3,1.41,10,0.2,0.818,0.1,0.295,0.295,0.717,0,0,-0.9,2
ENSMUSG00000003378,GRIK5,"glutamate receptor, ionotropic, kainate 5 (gamma 2)",endoplasmic reticulum|plasma membrane|ionotropic glutamate receptor complex|postsynaptic density|membrane|integral component of membrane|cell junction|axon|dendrite|dendrite|kainate selective glutamate receptor complex|presynaptic membrane|neuron projection|neuronal cell body|terminal bouton|perikaryon|synapse|postsynaptic membrane|,"protein retention in ER lumen|transport|ion transport|signal transduction|synaptic transmission|regulation of synaptic vesicle fusion to presynaptic membrane|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|regulation of membrane potential|receptor clustering|positive regulation of neuron apoptotic process|establishment of localization in cell|regulation of excitatory postsynaptic membrane potential|",receptor activity|ionotropic glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|glutamate receptor activity|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|SH3 domain binding|PDZ domain binding|identical protein binding|,10,-0.2,1.17,10,0,0,-0.1,0.288,-0.288,0.72,0,0,-1.7,1.1
ENSMUSG00000031891,HSD11B2,hydroxysteroid 11-beta dehydrogenase 2,cytoplasm|endoplasmic reticulum|intracellular membrane-bounded organelle|,regulation of blood volume by renal aldosterone|metabolic process|glucocorticoid metabolic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|steroid binding|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|NAD binding|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.1,0.167,10,-0.3,1,-0.2,0.285,-0.285,0.721,0,0,-1.3,1.5
ENSMUSG00000057280,MUSK,"muscle, skeletal, receptor tyrosine kinase",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|cell junction|neuromuscular junction|neuromuscular junction|cell projection|receptor complex|synapse|postsynaptic membrane|,"positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|regulation of transcription, DNA-templated|protein phosphorylation|signal transduction|multicellular organismal development|neuromuscular junction development|memory|regulation of synaptic growth at neuromuscular junction|positive regulation of gene expression|negative regulation of gene expression|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cell differentiation|positive regulation of synaptic transmission, cholinergic|receptor clustering|receptor clustering|receptor clustering|positive regulation of neuron apoptotic process|positive regulation of synaptic growth at neuromuscular junction|protein autophosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|response to electrical stimulus|long-term synaptic potentiation|skeletal muscle acetylcholine-gated channel clustering|positive regulation of protein geranylgeranylation|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|PDZ domain binding|",10,0,0,10,-0.4,1.79,-0.1,0.284,-0.284,0.721,0,0,-1.8,0.9
ENSMUSG00000024045,AKAP8,A kinase (PRKA) anchor protein 8,nuclear chromatin|condensed chromosome|condensed chromosome|female pronucleus|nucleus|nucleus|mitochondrion|Golgi apparatus|membrane|nuclear matrix|nuclear matrix|,mitotic chromosome condensation|mitotic chromosome condensation|phosphorylation|,DNA binding|chromatin binding|double-stranded DNA binding|protein binding|zinc ion binding|kinase activity|transferase activity|protein kinase A regulatory subunit binding|poly(A) RNA binding|metal ion binding|,10,-0.8,0.482,10,0.1,0.378,0.1,0.282,0.282,0.722,0,0,-2,0.9
ENSMUSG00000002341,NCAN,neurocan,extracellular region|,cell adhesion|regulation of synapse structural plasticity|,calcium ion binding|hyaluronic acid binding|carbohydrate binding|,10,-0.3,1.64,10,0.3,1.37,-0.2,0.274,-0.274,0.725,0,0,-1.5,1.3
ENSMUSG00000029521,CHEK2,checkpoint kinase 2,"chromosome, telomeric region|intracellular|nucleus|PML body|","DNA damage checkpoint|G2/M transition of mitotic cell cycle|DNA repair|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|cellular response to DNA damage stimulus|DNA damage induced protein phosphorylation|cell cycle|mitotic nuclear division|intrinsic apoptotic signaling pathway in response to DNA damage|response to gamma radiation|phosphorylation|regulation of protein catabolic process|signal transduction in response to DNA damage|signal transduction in response to DNA damage|cellular protein catabolic process|positive regulation of transcription, DNA-templated|protein autophosphorylation|protein stabilization|cell division|signal transduction involved in intra-S DNA damage checkpoint|spindle assembly involved in mitosis|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|ubiquitin protein ligase binding|identical protein binding|protein homodimerization activity|metal ion binding|",10,-0.1,0.0681,10,-0.7,0.577,-0.1,0.269,-0.269,0.727,0,0,-2,0.6
ENSMUSG00000038656,CYP3A16,"cytochrome P450, family 3, subfamily a, polypeptide 16",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|demethylation|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|demethylase activity|metal ion binding|testosterone 6-beta-hydroxylase activity|aromatase activity|",10,0.1,0.0356,10,-0.1,0.295,-0.1,0.268,-0.268,0.727,0,0,-1.5,1.5
ENSMUSG00000030630,FAH,fumarylacetoacetate hydrolase,extracellular vesicular exosome|,arginine catabolic process|L-phenylalanine catabolic process|tyrosine catabolic process|metabolic process|aromatic amino acid family metabolic process|,catalytic activity|fumarylacetoacetase activity|fumarylacetoacetase activity|hydrolase activity|metal ion binding|,9,-0.1,0.0916,9,-0.1,0.201,-0.1,0.267,-0.267,0.727,0,0,-1.7,1.2
ENSMUSG00000021032,NGB,neuroglobin,cytoplasm|mitochondrion|,transport|apoptotic process|oxygen transport|,oxygen transporter activity|iron ion binding|oxygen binding|heme binding|metal ion binding|,10,0.3,0.433,10,-0.1,0.12,0.1,0.262,0.262,0.729,0,0,-1.5,1.4
ENSMUSG00000030228,PIK3C2G,"phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide",nuclear envelope|Golgi apparatus|plasma membrane|plasma membrane|phosphatidylinositol 3-kinase complex|membrane|,chemotaxis|phosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|,"nucleotide binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|1-phosphatidylinositol-4-phosphate 3-kinase activity|1-phosphatidylinositol-4-phosphate 3-kinase activity|phosphatidylinositol binding|",10,0.1,0.653,10,0,0,0.1,0.26,0.26,0.73,0,0,-1.3,1.6
ENSMUSG00000021265,SLC25A29,"solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|acyl carnitine transport|organic cation transport|ion transmembrane transport|transmembrane transport|acyl carnitine transmembrane transport|,acyl carnitine transmembrane transporter activity|,10,0,0,10,-0.4,0.906,-0.1,0.26,-0.26,0.73,0,0,-1.7,1.1
ENSMUSG00000044005,GLS2,"glutaminase 2 (liver, mitochondrial)",mitochondrion|mitochondrion|,glutamine metabolic process|regulation of apoptotic process|reactive oxygen species metabolic process|,molecular_function|glutaminase activity|hydrolase activity|,10,0.3,1.35,10,-0.2,1.45,-0.1,0.251,-0.251,0.733,0,0,-2,1.2
ENSMUSG00000047976,KCNA1,"potassium voltage-gated channel, shaker-related subfamily, member 1",voltage-gated potassium channel complex|membrane|integral component of membrane|apical plasma membrane|dendrite|neuronal cell body|juxtaparanode region of axon|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.2,0.117,10,-0.1,0.183,-0.1,0.249,-0.249,0.734,0,0,-1.6,1.2
ENSMUSG00000024863,MBL2,mannose-binding lectin (protein C) 2,extracellular region|collagen trimer|extracellular space|extracellular space|,"complement activation, lectin pathway|complement activation, lectin pathway|complement activation, lectin pathway|complement activation, lectin pathway|immune system process|complement activation, classical pathway|negative regulation of growth of symbiont in host|negative regulation of growth of symbiont in host|innate immune response|negative regulation of viral process|positive regulation of phagocytosis|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|killing by host of symbiont cells|",protease binding|receptor binding|calcium ion binding|galactose binding|mannose binding|carbohydrate binding|protein self-association|calcium-dependent protein binding|phosphatidylinositol-4-phosphate binding|,10,-0.9,0.761,10,0.1,0.0985,0.1,0.249,0.249,0.734,0,0,-2,0.8
ENSMUSG00000033065,PFKM,"phosphofructokinase, muscle",cytoplasm|cytosol|6-phosphofructokinase complex|apical plasma membrane|extracellular vesicular exosome|sperm principal piece|,"fructose 6-phosphate metabolic process|glycolytic process|glycolytic process|glycolytic process|glycolytic process|metabolic process|phosphorylation|fructose 1,6-bisphosphate metabolic process|positive regulation of insulin secretion|glucose homeostasis|muscle cell cellular homeostasis|carbohydrate phosphorylation|carbohydrate phosphorylation|protein oligomerization|protein homotetramerization|glycolytic process through fructose-6-phosphate|",nucleotide binding|catalytic activity|6-phosphofructokinase activity|6-phosphofructokinase activity|6-phosphofructokinase activity|6-phosphofructokinase activity|protein binding|ATP binding|protein C-terminus binding|phosphofructokinase activity|phosphofructokinase activity|AMP binding|kinase activity|transferase activity|kinase binding|carbohydrate binding|identical protein binding|protein homodimerization activity|metal ion binding|fructose binding|fructose-6-phosphate binding|,10,0.1,0.378,10,-0.2,1.4,-0.1,0.248,-0.248,0.734,0,0,-1.5,1.4
ENSMUSG00000068587,MGAM,maltase-glucoamylase,extracellular vesicular exosome|,metabolic process|,"glucan 1,4-alpha-glucosidase activity|alpha-glucosidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|maltose alpha-glucosidase activity|",10,-0.3,0.857,10,0,0,-0.1,0.243,-0.243,0.736,0,0,-1.8,1
ENSMUSG00000031481,TPTE,transmembrane phosphatase with tensin homology,Golgi apparatus|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.2,0.955,10,0,0,0.2,0.243,0.243,0.736,0,0,-1.1,1.7
ENSMUSG00000052738,SUCLG1,"succinate-CoA ligase, GDP-forming, alpha subunit",mitochondrion|mitochondrion|mitochondrial inner membrane|protein complex|succinate-CoA ligase complex (GDP-forming)|extracellular vesicular exosome|,tricarboxylic acid cycle|succinyl-CoA metabolic process|succinate metabolic process|metabolic process|,nucleotide binding|catalytic activity|ATP citrate synthase activity|succinate-CoA ligase (ADP-forming) activity|succinate-CoA ligase (GDP-forming) activity|GTP binding|ligase activity|GDP binding|poly(A) RNA binding|protein heterodimerization activity|cofactor binding|,10,-0.1,0.181,10,-0.1,0.0827,-0.1,0.241,-0.241,0.737,0,0,-1.9,1
ENSMUSG00000037885,STK35,serine/threonine kinase 35,cellular_component|nucleus|cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-0.7,1.48,-0.1,0.241,-0.241,0.737,0,0,-1.8,1.4
ENSMUSG00000026749,NEK6,NIMA (never in mitosis gene a)-related expressed kinase 6,nucleus|cytoplasm|cytoplasm|cytoskeleton|,protein phosphorylation|apoptotic process|cell cycle|chromosome segregation|mitotic nuclear division|signal transduction|phosphorylation|peptidyl-serine phosphorylation|regulation of mitotic metaphase/anaphase transition|G2 DNA damage checkpoint|positive regulation of I-kappaB kinase/NF-kappaB signaling|protein autophosphorylation|cell division|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|signal transducer activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|kinesin binding|protein kinase binding|metal ion binding|",10,-0.2,0.473,10,0.4,0.977,-0.1,0.235,-0.235,0.739,0,0,-1.1,1.7
ENSMUSG00000034974,DAPK3,death-associated protein kinase 3,"chromosome, centromeric region|nucleus|nucleus|chromosome|cytoplasm|cytoskeleton|PML body|membrane raft|","transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|phosphorylation|chromatin modification|negative regulation of translation|intracellular signal transduction|intracellular signal transduction|regulation of apoptotic process|protein autophosphorylation|cellular response to interferon-gamma|cellular response to interferon-gamma|positive regulation of canonical Wnt signaling pathway|apoptotic signaling pathway|apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|protein binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|protein homodimerization activity|leucine zipper domain binding|",10,0,0,10,-0.6,0.721,-0.1,0.233,-0.233,0.74,0,0,-2,0.7
ENSMUSG00000048310,PSKH1,protein serine kinase H1,cellular_component|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|cytoskeleton|plasma membrane|membrane|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.5,0.91,10,-0.2,0.864,0.1,0.23,0.23,0.741,0,0,-1.2,1.6
ENSMUSG00000032845,ALPK2,alpha-kinase 2,nucleus|,protein phosphorylation|biological_process|phosphorylation|,"molecular_function|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|ATP binding|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,-0.1,0.104,10,0.1,0.668,0.1,0.226,0.226,0.743,0,0,-1.5,1.3
ENSMUSG00000025716,MYO3A,myosin IIIA,photoreceptor inner segment|cytoplasm|cytoskeleton|myosin complex|filopodium|filamentous actin|stereocilium bundle tip|filopodium tip|,ATP catabolic process|protein phosphorylation|visual perception|sensory perception of sound|sensory perception of sound|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|protein autophosphorylation|protein autophosphorylation|inner ear development|response to stimulus|positive regulation of filopodium assembly|,"microfilament motor activity|microfilament motor activity|nucleotide binding|motor activity|actin binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|actin-dependent ATPase activity|ADP binding|actin filament binding|plus-end directed microfilament motor activity|",10,-0.2,0.408,10,0.4,1.77,0.1,0.221,0.221,0.744,0,0,-1,1.8
ENSMUSG00000032937,FSHR,follicle stimulating hormone receptor,endosome|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|,"ovarian follicle development|primary ovarian follicle growth|regulation of protein phosphorylation|regulation of systemic arterial blood pressure|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|spermatogenesis|spermatid development|locomotory behavior|cellular water homeostasis|regulation of platelet-derived growth factor receptor signaling pathway|ovulation cycle process|neuron projection development|regulation of hormone metabolic process|regulation of chromosome organization|regulation of intracellular estrogen receptor signaling pathway|positive regulation of intracellular estrogen receptor signaling pathway|sperm chromatin condensation|spermatogenesis, exchange of chromosomal proteins|follicle-stimulating hormone signaling pathway|follicle-stimulating hormone signaling pathway|regulation of MAPK cascade|transcytosis|regulation of osteoclast differentiation|negative regulation of bone resorption|Sertoli cell development|Sertoli cell proliferation|uterus development|regulation of acetylcholine metabolic process|basement membrane organization|",signal transducer activity|G-protein coupled receptor activity|follicle-stimulating hormone receptor activity|follicle-stimulating hormone receptor activity|protein-hormone receptor activity|peptide hormone binding|,10,0.1,0.0102,10,0.2,0.292,0.1,0.221,0.221,0.744,0,0,-1.2,1.7
ENSMUSG00000031883,CAR7,carbonic anhydrase 7,cytoplasm|cytosol|,"one-carbon metabolic process|positive regulation of synaptic transmission, GABAergic|positive regulation of cellular pH reduction|regulation of chloride transport|",carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,0.2,0.261,10,-0.9,1.7,-0.1,0.219,-0.219,0.745,0,0,-2,0.8
ENSMUSG00000002625,AKAP8L,A kinase (PRKA) anchor protein 8-like,nucleus|cytoplasm|nuclear matrix|nuclear matrix|,biological_process|phosphorylation|,DNA binding|kinase activity|transferase activity|poly(A) RNA binding|metal ion binding|,10,0.2,0.975,10,0,0,0.1,0.218,0.218,0.746,0,0,-1.2,1.7
ENSMUSG00000075270,PDE11A,phosphodiesterase 11A,cytoplasm|perikaryon|,cAMP catabolic process|signal transduction|metabolic process|cGMP catabolic process|,"catalytic activity|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|cAMP binding|cGMP binding|metal ion binding|3',5'-cyclic-GMP phosphodiesterase activity|",10,0.2,0.308,10,-0.1,0.238,-0.1,0.217,-0.217,0.746,0,0,-1.5,1.3
ENSMUSG00000041769,PPP2R2D,"protein phosphatase 2, regulatory subunit B, delta",protein phosphatase type 2A complex|cytoplasm|,cell cycle|mitotic nuclear division|signal transduction|cell division|,protein phosphatase type 2A regulator activity|,10,0,0,10,-0.1,0.47,-0.1,0.207,-0.207,0.75,0,0,-1.8,1.1
ENSMUSG00000034902,PIP5K1C,"phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma",cell|cytoplasm|plasma membrane|membrane|cell junction|cell projection|,exocytosis|endocytosis|phagocytosis|chemotaxis|cytoskeletal anchoring at plasma membrane|cell adhesion|axonogenesis|phosphorylation|phosphatidylinositol metabolic process|phosphatidylinositol phosphorylation|platelet aggregation|,nucleotide binding|protein binding|ATP binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|transferase activity|talin binding|,10,0.3,0.332,10,0,0,0.2,0.206,0.206,0.75,0,0,-1.1,1.7
ENSMUSG00000002771,GRIN2D,"glutamate receptor, ionotropic, NMDA2D (epsilon 4)",plasma membrane|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|dendrite|synapse|postsynaptic membrane|,"startle response|transport|ion transport|cation transport|adult locomotory behavior|ion transmembrane transport|regulation of ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|synaptic transmission, glutamatergic|regulation of sensory perception of pain|",receptor activity|ionotropic glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|cation channel activity|glutamate binding|voltage-gated cation channel activity|neurotransmitter binding|,10,0.4,2.03,10,-0.1,0.329,0.1,0.204,0.204,0.751,0,0,-1.4,1.4
ENSMUSG00000025905,OPRK1,"opioid receptor, kappa 1",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,immune response|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|behavior|locomotory behavior|sensory perception of pain|adenylate cyclase-inhibiting opioid receptor signaling pathway|opioid receptor signaling pathway|opioid receptor signaling pathway|regulation of saliva secretion|defense response to virus|,signal transducer activity|G-protein coupled receptor activity|opioid receptor activity|opioid receptor activity|opioid receptor activity|dynorphin receptor activity|,10,-0.4,1.09,10,0.4,0.786,0.1,0.203,0.203,0.752,0,0,-1.5,1.6
ENSMUSG00000020785,CAMKK1,"calcium/calmodulin-dependent protein kinase kinase 1, alpha",nucleus|cytoplasm|,protein phosphorylation|phosphorylation|activation of protein kinase activity|positive regulation of protein kinase activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin-dependent protein kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-0.2,0.301,-0.1,0.203,-0.203,0.752,0,0,-1.3,1.5
ENSMUSG00000000794,KCNN3,"potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3",cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|filopodium|neuromuscular junction|neuron projection|neuronal cell body|neuronal cell body|cell body|,transport|ion transport|potassium ion transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,calmodulin binding|calcium-activated potassium channel activity|small conductance calcium-activated potassium channel activity|small conductance calcium-activated potassium channel activity|protein heterodimerization activity|,10,-0.2,0.211,10,-0.1,0.0431,-0.1,0.201,-0.201,0.753,0,0,-1.8,1
ENSMUSG00000069094,PDE7A,phosphodiesterase 7A,None,signal transduction|,"cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|",10,-0.2,0.534,10,0.1,0.126,-0.1,0.198,-0.198,0.754,0,0,-1.5,1.3
ENSMUSG00000050860,PHOSPHO1,"phosphatase, orphan 1",extracellular matrix|extracellular matrix|extracellular membrane-bounded organelle|extracellular membrane-bounded organelle|,endochondral ossification|metabolic process|dephosphorylation|regulation of bone mineralization|bone mineralization involved in bone maturation|,pyrophosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|phosphocholine phosphatase activity|phosphoethanolamine phosphatase activity|,9,-0.1,0.328,9,0.4,0.434,-0.1,0.196,-0.196,0.755,0,0,-1.2,1.8
ENSMUSG00000030981,MMP21,matrix metallopeptidase 21,extracellular region|extracellular matrix|,hematopoietic progenitor cell differentiation|proteolysis|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.2,0.327,10,0,0,0.1,0.194,0.194,0.756,0,0,-1.3,1.6
ENSMUSG00000026604,PTPN14,"protein tyrosine phosphatase, non-receptor type 14",nucleus|cytoplasm|cytoskeleton|,"lymphangiogenesis|lymphangiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|protein dephosphorylation|negative regulation of cell proliferation|dephosphorylation|peptidyl-tyrosine dephosphorylation|regulation of protein export from nucleus|regulation of RNA biosynthetic process|",transcription cofactor activity|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|receptor tyrosine kinase binding|,10,0.3,0.745,10,0,0,0.2,0.193,0.193,0.756,0,0,-0.8,1.9
ENSMUSG00000043613,MMP3,matrix metallopeptidase 3,extracellular region|proteinaceous extracellular matrix|extracellular space|nucleus|dendrite|extracellular matrix|protein complex|cell body|,proteolysis|proteolysis|negative regulation of hydrogen peroxide metabolic process|regulation of cell migration|collagen catabolic process|cellular response to amino acid stimulus|,endopeptidase activity|metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|protein complex binding|metal ion binding|,10,-0.1,0.0689,10,-0.2,0.193,-0.1,0.191,-0.191,0.757,0,0,-1.5,1.4
ENSMUSG00000037887,DUSP8,dual specificity phosphatase 8,nucleus|cytoplasm|,protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,9,0,0,9,-0.3,1.32,-0.2,0.187,-0.187,0.759,0,0,-1.6,1.3
ENSMUSG00000021820,CAMK2G,calcium/calmodulin-dependent protein kinase II gamma,membrane|membrane|sarcoplasmic reticulum|,G1/S transition of mitotic cell cycle|response to hypoxia|protein phosphorylation|calcium ion transport|response to oxidative stress|multicellular organismal development|nervous system development|phosphorylation|cell differentiation|protein autophosphorylation|protein autophosphorylation|regulation of relaxation of cardiac muscle|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.276,9,0,0,-0.1,0.186,-0.186,0.759,0,0,-1.7,1.2
ENSMUSG00000032058,PPP2R1B,"protein phosphatase 2, regulatory subunit A, beta",membrane raft|,apoptotic process involved in morphogenesis|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,protein binding|,10,-0.7,0.641,10,-0.1,0.118,-0.1,0.185,-0.185,0.759,0,0,-2,0.5
ENSMUSG00000020601,TRIB2,tribbles homolog 2 (Drosophila),cytoplasm|cytoskeleton|,protein phosphorylation|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of interleukin-10 biosynthetic process|negative regulation of fat cell differentiation|regulation of catalytic activity|positive regulation of ubiquitin-protein transferase activity|,"protein kinase activity|protein kinase inhibitor activity|ATP binding|transcription factor binding|transferase activity, transferring phosphorus-containing groups|ubiquitin protein ligase binding|ubiquitin-protein transferase regulator activity|",10,-0.3,1.81,10,0,0,-0.1,0.178,-0.178,0.762,0,0,-1.8,0.9
ENSMUSG00000023031,CELA1,"chymotrypsin-like elastase family, member 1",extracellular region|,negative regulation of transcription from RNA polymerase II promoter|proteolysis|inflammatory response|post-embryonic development|Wnt signaling pathway|exocrine pancreas development|multicellular organism growth|regulation of cell proliferation|regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|digestive system development|pancreas morphogenesis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|metal ion binding|,10,-0.1,0.139,10,0.1,0.681,0.1,0.178,0.178,0.762,0,0,-1.4,1.5
ENSMUSG00000024789,JAK2,Janus kinase 2,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytoskeleton|caveola|membrane|nuclear matrix|membrane raft|,"activation of MAPKK activity|immune system process|protein phosphorylation|activation of cysteine-type endopeptidase activity involved in apoptotic process|response to oxidative stress|signal transduction|enzyme linked receptor protein signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|JAK-STAT cascade|JAK-STAT cascade|JAK-STAT cascade|tyrosine phosphorylation of STAT protein|tyrosine phosphorylation of STAT protein|STAT protein import into nucleus|positive regulation of cell proliferation|negative regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to oxidative stress|hormone-mediated signaling pathway|positive regulation of cell-substrate adhesion|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|chromatin modification|peptidyl-tyrosine phosphorylation|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|negative regulation of cell-cell adhesion|myeloid cell differentiation|cell differentiation|erythrocyte differentiation|positive regulation of cell migration|axon regeneration|mineralocorticoid receptor signaling pathway|positive regulation of insulin secretion|response to lipopolysaccharide|positive regulation of phosphoprotein phosphatase activity|positive regulation of interleukin-1 beta production|positive regulation of tumor necrosis factor production|positive regulation of protein import into nucleus, translocation|response to hydroperoxide|tumor necrosis factor-mediated signaling pathway|host programmed cell death induced by symbiont|response to tumor necrosis factor|histone H3-Y41 phosphorylation|intracellular signal transduction|interleukin-12-mediated signaling pathway|tyrosine phosphorylation of Stat3 protein|tyrosine phosphorylation of Stat5 protein|tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|activation of JAK2 kinase activity|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of DNA binding|negative regulation of DNA binding|negative regulation of neuron apoptotic process|innate immune response|positive regulation of nitric oxide biosynthetic process|positive regulation of cell differentiation|negative regulation of heart contraction|response to antibiotic|protein autophosphorylation|protein autophosphorylation|platelet-derived growth factor receptor signaling pathway|regulation of inflammatory response|positive regulation of inflammatory response|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of cell activation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase biosynthetic process|interferon-gamma-mediated signaling pathway|growth hormone receptor signaling pathway|JAK-STAT cascade involved in growth hormone signaling pathway|JAK-STAT cascade involved in growth hormone signaling pathway|JAK-STAT cascade involved in growth hormone signaling pathway|positive regulation of growth hormone receptor signaling pathway|mammary gland epithelium development|response to interleukin-12|response to granulocyte macrophage colony-stimulating factor|extrinsic apoptotic signaling pathway|activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|positive regulation of apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|receptor binding|growth hormone receptor binding|interleukin-12 receptor binding|protein binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|heme binding|type 1 angiotensin receptor binding|acetylcholine receptor binding|histone kinase activity (H3-Y41 specific)|SH2 domain binding|histone binding|phosphatidylinositol 3-kinase binding|insulin receptor substrate binding|peptide hormone receptor binding|",10,0,0,10,-0.3,1.09,-0.1,0.176,-0.176,0.763,0,0,-1.7,1.1
ENSMUSG00000028138,ADH5,"alcohol dehydrogenase 5 (class III), chi polypeptide",nucleus|cytoplasm|mitochondrion|extracellular vesicular exosome|,retinoid metabolic process|respiratory system process|ethanol catabolic process|ethanol oxidation|peptidyl-cysteine S-nitrosylation|response to lipopolysaccharide|positive regulation of blood pressure|formaldehyde catabolic process|response to nitrosative stress|response to redox state|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase (NAD) activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|fatty acid binding|zinc ion binding|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|formaldehyde dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|protein homodimerization activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|metal ion binding|3-ketoglucose-reductase activity|S-(hydroxymethyl)glutathione dehydrogenase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,-0.9,0.412,10,-0.1,0.437,-0.1,0.174,-0.174,0.763,0,0,-2,0.9
ENSMUSG00000018196,GLRX2,glutaredoxin 2 (thioltransferase),nucleus|mitochondrion|mitochondrion|,transport|response to organic substance|response to hydrogen peroxide|cell redox homeostasis|oxidation-reduction process|,"electron carrier activity|protein disulfide oxidoreductase activity|transferase activity|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,-0.4,1.6,10,0.1,0.294,0.1,0.173,0.173,0.764,0,0,-1.8,1
ENSMUSG00000039194,RLBP1,retinaldehyde binding protein 1,intracellular|cytoplasm|cell body|,transport|visual perception|response to stimulus|,transporter activity|11-cis retinal binding|retinol binding|,9,-0.1,0.0571,9,-0.4,0.805,-0.1,0.171,-0.171,0.765,0,0,-1.8,1.1
ENSMUSG00000029484,ANXA3,annexin A3,cytoplasm|plasma membrane|membrane|axon|dendrite|phagocytic vesicle membrane|specific granule|neuronal cell body|extracellular vesicular exosome|,phagocytosis|positive regulation of endothelial cell migration|defense response to bacterium|negative regulation of catalytic activity|neutrophil degranulation|positive regulation of angiogenesis|positive regulation of DNA metabolic process|positive regulation of sequence-specific DNA binding transcription factor activity|,phospholipase inhibitor activity|calcium ion binding|calcium-dependent phospholipid binding|phospholipase A2 inhibitor activity|calcium-dependent protein binding|,10,0.4,0.719,10,0,0,0.1,0.167,0.167,0.766,0,0,-0.9,1.9
ENSMUSG00000020841,CPD,carboxypeptidase D,nucleus|trans-Golgi network|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,proteolysis|,carboxypeptidase activity|metallocarboxypeptidase activity|serine-type carboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.8,1.61,-0.1,0.166,-0.166,0.766,0,0,-2,1
ENSMUSG00000038582,PPTC7,PTC7 protein phosphatase homolog (S. cerevisiae),mitochondrion|,biological_process|,molecular_function|catalytic activity|phosphoprotein phosphatase activity|hydrolase activity|metal ion binding|,10,0.2,1.19,10,-0.1,0.294,0.1,0.159,0.159,0.769,0,0,-1.1,1.7
ENSMUSG00000055254,NTRK2,"neurotrophic tyrosine kinase, receptor, type 2",intracellular|cell|cytoplasm|endosome|rough endoplasmic reticulum|cytosol|plasma membrane|plasma membrane|integral component of plasma membrane|cell surface|postsynaptic density|membrane|integral component of membrane|axon|dendrite|growth cone|neuronal cell body|terminal bouton|dendritic spine|perikaryon|receptor complex|axon terminus|postsynaptic membrane|presynaptic active zone|excitatory synapse|neuronal postsynaptic density|,"vasculogenesis|neuron migration|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|neuromuscular junction development|learning|long-term memory|feeding behavior|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of neuron projection development|glutamate secretion|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|regulation of metabolic process|central nervous system neuron development|cerebral cortex development|cell differentiation|neuron differentiation|brain-derived neurotrophic factor receptor signaling pathway|brain-derived neurotrophic factor receptor signaling pathway|regulation of Rac GTPase activity|calcium-mediated signaling using intracellular calcium source|neurotrophin signaling pathway|neurotrophin signaling pathway|mechanoreceptor differentiation|regulation of MAPK cascade|positive regulation of MAPK cascade|negative regulation of neuron apoptotic process|retinal rod cell development|protein autophosphorylation|regulation of neurotransmitter secretion|oligodendrocyte differentiation|peripheral nervous system neuron development|positive regulation of axonogenesis|regulation of dendrite development|regulation of protein kinase B signaling|positive regulation of synaptic transmission, glutamatergic|long-term synaptic potentiation|negative regulation of anoikis|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|neurotrophin receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|neurotrophin binding|neurotrophin binding|ephrin receptor binding|brain-derived neurotrophic factor binding|brain-derived neurotrophic factor binding|brain-derived neurotrophic factor-activated receptor activity|brain-derived neurotrophic factor-activated receptor activity|",10,0.9,1.49,10,0,0,0.1,0.158,0.158,0.77,0,0,-0.5,2
ENSMUSG00000003534,DDR1,"discoidin domain receptor family, member 1",extracellular space|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|receptor complex|extracellular vesicular exosome|,"regulation of cell growth|regulation of cell-matrix adhesion|protein phosphorylation|cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|female pregnancy|embryo implantation|lactation|negative regulation of cell proliferation|regulation of extracellular matrix disassembly|regulation of extracellular matrix disassembly|smooth muscle cell migration|smooth muscle cell migration|phosphorylation|peptidyl-tyrosine phosphorylation|collagen-activated tyrosine kinase receptor signaling pathway|collagen-activated tyrosine kinase receptor signaling pathway|peptidyl-tyrosine autophosphorylation|ear development|wound healing, spreading of cells|wound healing, spreading of cells|protein autophosphorylation|branching involved in mammary gland duct morphogenesis|mammary gland alveolus development|smooth muscle cell-matrix adhesion|smooth muscle cell-matrix adhesion|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|collagen binding|collagen binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein tyrosine kinase collagen receptor activity|metal ion binding|",10,0.4,0.726,10,0,0,0.1,0.155,0.155,0.771,0,0,-1.2,1.7
ENSMUSG00000002103,ACP2,"acid phosphatase 2, lysosomal",lysosome|lysosome|lysosome|membrane|membrane|integral component of membrane|cytoplasmic vesicle|neuron projection|extracellular vesicular exosome|,skeletal system development|lysosome organization|response to organic substance|dephosphorylation|dephosphorylation|autophagic cell death|,phosphotyrosine binding|acid phosphatase activity|acid phosphatase activity|acid phosphatase activity|phosphoprotein phosphatase activity|hydrolase activity|,10,-0.1,0.249,10,0.2,0.623,0.1,0.149,0.149,0.773,0,0,-1.3,1.6
ENSMUSG00000025793,HGS,HGF-regulated tyrosine kinase substrate,cytoplasm|cytoplasm|endosome|early endosome|cytosol|membrane|secretory granule|intracellular membrane-bounded organelle|extracellular vesicular exosome|,transport|intracellular protein transport|endosome to lysosome transport|protein transport|negative regulation of JAK-STAT cascade|,protein domain specific binding|metal ion binding|,4,0.7,1.4,3,-0.1,0.0981,-0.1,0.149,-0.149,0.773,0,0,-1.5,2
ENSMUSG00000040918,SLC19A2,"solute carrier family 19 (thiamine transporter), member 2",plasma membrane|plasma membrane|plasma membrane|,drug transmembrane transport|thiamine transport|thiamine transmembrane transport|thiamine transmembrane transport|,thiamine transmembrane transporter activity|thiamine uptake transmembrane transporter activity|thiamine uptake transmembrane transporter activity|,10,-0.1,0.246,10,0,0,-0.1,0.149,-0.149,0.773,0,0,-1.4,1.4
ENSMUSG00000030247,KCNJ8,"potassium inwardly-rectifying channel, subfamily J, member 8",mitochondrion|ATP-sensitive potassium channel complex|membrane|integral component of membrane|myofibril|sarcolemma|intracellular membrane-bounded organelle|,transport|ion transport|potassium ion transport|heart development|response to pH|potassium ion import|response to lipopolysaccharide|regulation of ion transmembrane transport|vasodilation|response to exogenous dsRNA|defense response to virus|,inward rectifier potassium channel activity|voltage-gated ion channel activity|ATP binding|ATP-activated inward rectifier potassium channel activity|sulfonylurea receptor binding|,10,0.1,0.428,10,0,0,0.1,0.148,0.148,0.774,0,0,-1.1,1.8
ENSMUSG00000032601,PRKAR2A,"protein kinase, cAMP dependent regulatory, type II alpha",cytoplasm|centrosome|plasma membrane|cAMP-dependent protein kinase complex|membrane|membrane|T-tubule|AMP-activated protein kinase complex|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,regulation of protein phosphorylation|phosphorylation|regulation of protein kinase activity|protein heterooligomerization|negative regulation of cAMP-dependent protein kinase activity|,nucleotide binding|cAMP-dependent protein kinase inhibitor activity|protein binding|cAMP-dependent protein kinase regulator activity|kinase activity|transferase activity|protein domain specific binding|cAMP binding|ubiquitin protein ligase binding|protein kinase A catalytic subunit binding|small molecule binding|protein homodimerization activity|,10,-0.2,0.264,10,0,0,-0.2,0.148,-0.148,0.774,0,0,-1.9,0.9
ENSMUSG00000029193,CCKAR,cholecystokinin A receptor,cytoplasm|lysosome|endosome|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|terminal bouton|,temperature homeostasis|gastric acid secretion|neuron migration|reduction of food intake in response to dietary excess|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|axonogenesis|feeding behavior|response to heat|insulin secretion|pancreatic juice secretion|forebrain development|actin cytoskeleton reorganization|cholecystokinin signaling pathway|response to starvation|eating behavior|regulation of potassium ion transport|regulation of hormone secretion|regulation of calcium ion transport|positive regulation of somatostatin secretion|,signal transducer activity|G-protein coupled receptor activity|cholecystokinin receptor activity|,10,0,0,10,-0.1,0.263,-0.1,0.145,-0.145,0.775,0,0,-1.8,1
ENSMUSG00000035403,CRB2,crumbs homolog 2 (Drosophila),membrane|integral component of membrane|protein complex|extracellular vesicular exosome|,mesoderm formation|somitogenesis|positive regulation of epithelial to mesenchymal transition|negative regulation of endopeptidase activity|notochord formation|positive regulation of BMP signaling pathway|maintenance of epithelial cell apical/basal polarity|response to stimulus|cardiovascular system development|,calcium ion binding|aspartic-type endopeptidase inhibitor activity|enzyme binding|,10,0,0,10,-0.3,0.796,-0.2,0.144,-0.144,0.775,0,0,-1.7,1.1
ENSMUSG00000063410,STK24,serine/threonine kinase 24,nucleus|nucleolus|cytoplasm|membrane|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|apoptotic process|intrinsic apoptotic signaling pathway in response to oxidative stress|phosphorylation|signal transduction by phosphorylation|negative regulation of cell migration|protein autophosphorylation|regulation of axon regeneration|positive regulation of axon regeneration|execution phase of apoptosis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0,0,10,-0.1,0.492,-0.1,0.14,-0.14,0.777,0,0,-1.8,1.1
ENSMUSG00000035885,COX8A,cytochrome c oxidase subunit VIIIa,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,None,cytochrome-c oxidase activity|,10,0.1,0.0594,10,-0.2,0.916,-0.1,0.137,-0.137,0.778,0,0,-1.7,1.1
ENSMUSG00000033949,TRIM36,tripartite motif-containing 36,acrosomal vesicle|intracellular|cell|cytoplasm|cytoskeleton|cytoplasmic vesicle|extracellular vesicular exosome|,acrosome reaction|regulation of cell cycle|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.153,10,0.3,1.8,0.1,0.132,0.132,0.78,0,0,-1,1.8
ENSMUSG00000044288,CNR1,cannabinoid receptor 1 (brain),plasma membrane|membrane|integral component of membrane|axon|growth cone|intracellular membrane-bounded organelle|,"positive regulation of acute inflammatory response to antigenic stimulus|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|axonal fasciculation|aging|learning or memory|memory|positive regulation of neuron projection development|regulation of lipid metabolic process|sensory perception of pain|positive regulation of fever generation|negative regulation of fatty acid beta-oxidation|regulation of synaptic transmission, GABAergic|response to lipopolysaccharide|negative regulation of mast cell activation|negative regulation of dopamine secretion|response to nicotine|cannabinoid signaling pathway|response to cocaine|glucose homeostasis|positive regulation of apoptotic process|negative regulation of ion transport|response to morphine|response to ethanol|negative regulation of action potential|negative regulation of blood pressure|positive regulation of blood pressure|regulation of insulin secretion|negative regulation of nitric-oxide synthase activity|regulation of synaptic transmission, glutamatergic|regulation of feeding behavior|regulation of penile erection|",signal transducer activity|G-protein coupled receptor activity|cannabinoid receptor activity|drug binding|,10,0.3,1.15,10,0,0,0.1,0.119,0.119,0.785,0,0,-1.6,1.4
ENSMUSG00000022901,CD86,CD86 antigen,plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,toll-like receptor signaling pathway|immune system process|negative regulation of T cell anergy|positive regulation of T cell proliferation|positive regulation of T cell proliferation|positive regulation of activated T cell proliferation|B cell activation|defense response to virus|,receptor binding|,10,0.1,0.0711,10,-0.4,1.43,-0.2,0.118,-0.118,0.785,0,0,-1.7,1.1
ENSMUSG00000055026,GABRG3,"gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3",plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|signal transduction|gamma-aminobutyric acid signaling pathway|response to drug|chloride transmembrane transport|,GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|,10,0.4,2.27,10,0,0,0.1,0.107,0.107,0.79,0,0,-0.9,1.8
ENSMUSG00000000805,CAR4,carbonic anhydrase 4,rough endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|trans-Golgi network|plasma membrane|cell surface|membrane|apical plasma membrane|sarcoplasmic reticulum|transport vesicle membrane|secretory granule membrane|anchored component of membrane|anchored component of external side of plasma membrane|brush border membrane|sarcolemma|anchored component of plasma membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,one-carbon metabolic process|regulation of pH|carbon dioxide transport|bicarbonate transport|,carbonate dehydratase activity|carbonate dehydratase activity|protein binding|zinc ion binding|lyase activity|metal ion binding|,10,0.1,0.315,10,0,0,0.1,0.105,0.105,0.791,0,0,-1.7,1.3
ENSMUSG00000020125,ELANE,"elastase, neutrophil expressed",cytoplasm|cytoplasm|cell surface|transcriptional repressor complex|secretory granule|extracellular vesicular exosome|,negative regulation of transcription from RNA polymerase II promoter|response to yeast|acute inflammatory response to antigenic stimulus|transcription from RNA polymerase II promoter|proteolysis|proteolysis|phagocytosis|response to UV|response to lipopolysaccharide|response to lipopolysaccharide|defense response to bacterium|negative regulation of growth of symbiont in host|negative regulation of growth of symbiont in host|negative regulation of chemokine biosynthetic process|negative regulation of interleukin-8 biosynthetic process|positive regulation of interleukin-8 biosynthetic process|positive regulation of smooth muscle cell proliferation|positive regulation of immune response|positive regulation of immune response|defense response to fungus|defense response to fungus|leukocyte migration|neutrophil mediated killing of fungus|,RNA polymerase II transcription corepressor activity|protease binding|catalytic activity|endopeptidase activity|serine-type endopeptidase activity|heparin binding|peptidase activity|serine-type peptidase activity|hydrolase activity|cytokine binding|,10,-0.1,0.0619,10,-0.1,0.0531,-0.1,0.105,-0.105,0.791,0,0,-1.6,1.3
ENSMUSG00000052922,BPI,bactericidal permeablility increasing protein,extracellular region|cytoplasm|cytoplasm|membrane|extracellular vesicular exosome|,immune response|negative regulation of interleukin-6 production|negative regulation of interleukin-8 production|negative regulation of tumor necrosis factor production|defense response to bacterium|negative regulation of macrophage activation|,lipopolysaccharide binding|lipid binding|,10,-0.1,0.167,10,0.1,0.149,0.1,0.101,0.101,0.793,0,0,-1.3,1.7
ENSMUSG00000028348,MURC,muscle-related coiled-coil protein,cytoplasm|cytoplasm|Z disc|Z disc|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Rho protein signal transduction|multicellular organismal development|muscle organ development|cell differentiation|positive regulation of Rho GTPase activity|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cardiac myofibril assembly|",Rho GTPase activator activity|,10,0.1,0.2,10,-0.1,0.0132,-0.1,0.099,-0.099,0.793,0,0,-1.5,1.4
ENSMUSG00000021585,CAST,calpastatin,nucleus|cytoplasm|cytosol|membrane|membrane|,egg activation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|protein catabolic process|negative regulation of catalytic activity|negative regulation of cell cycle arrest|negative regulation of type B pancreatic cell apoptotic process|,protease binding|cysteine-type endopeptidase inhibitor activity|calcium-dependent cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|poly(A) RNA binding|,10,0,0,10,0.7,2.58,0.2,0.0989,0.0989,0.794,0,0,-0.9,2
ENSMUSG00000074240,CIB3,calcium and integrin binding family member 3,cellular_component|,biological_process|,molecular_function|calcium ion binding|metal ion binding|,10,0.4,1.1,10,-0.1,0.179,-0.1,0.0962,-0.0962,0.795,0,0,-1.3,1.7
ENSMUSG00000028048,GBA,"glucosidase, beta, acid",lysosome|lysosomal membrane|lysosomal membrane|membrane|lysosomal lumen|extracellular vesicular exosome|,carbohydrate metabolic process|lipid metabolic process|sphingolipid metabolic process|glucosylceramide catabolic process|metabolic process|response to pH|termination of signal transduction|negative regulation of interleukin-6 production|regulation of water loss via skin|response to testosterone|positive regulation of protein dephosphorylation|negative regulation of MAP kinase activity|skin morphogenesis|response to estrogen|sphingosine biosynthetic process|ceramide biosynthetic process|response to glucocorticoid|cellular response to tumor necrosis factor|response to thyroid hormone|,"glucosylceramidase activity|receptor binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.1,0.578,10,-0.1,0.0262,-0.1,0.0941,-0.0941,0.796,0,0,-1.3,1.9
ENSMUSG00000020142,SLC1A4,"solute carrier family 1 (glutamate/neutral amino acid transporter), member 4",centrosome|microtubule organizing center|intermediate filament|membrane|membrane|integral component of membrane|dendrite|neuronal cell body|extracellular vesicular exosome|,amino acid transmembrane transport|transport|chloride transport|dicarboxylic acid transport|neutral amino acid transport|L-alanine transport|proline transport|L-serine transport|threonine transport|hydroxyproline transport|proline transmembrane transport|cognition|L-alpha-amino acid transmembrane transport|chloride transmembrane transport|,chloride channel activity|neutral amino acid transmembrane transporter activity|L-alanine transmembrane transporter activity|L-proline transmembrane transporter activity|L-serine transmembrane transporter activity|L-threonine transmembrane transporter activity|symporter activity|sodium:dicarboxylate symporter activity|L-hydroxyproline transmembrane transporter activity|,10,-0.8,0.418,10,0,0,0.1,0.0915,0.0915,0.797,0,0,-2,1
ENSMUSG00000034837,GNAT1,"guanine nucleotide binding protein, alpha transducing 1",photoreceptor outer segment|photoreceptor outer segment|photoreceptor inner segment|cytoplasm|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|membrane|apical plasma membrane|photoreceptor connecting cilium|neuronal cell body|,"detection of chemical stimulus involved in sensory perception of bitter taste|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|visual perception|visual perception|phototransduction|phototransduction, visible light|cell proliferation|response to light intensity|rhodopsin mediated signaling pathway|eye photoreceptor cell development|response to stimulus|detection of light stimulus involved in visual perception|detection of light stimulus involved in visual perception|sensory perception of umami taste|positive regulation of cyclic-nucleotide phosphodiesterase activity|retina development in camera-type eye|cellular response to electrical stimulus|",nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|GTPase activity|signal transducer activity|protein binding|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,0,0,10,-0.2,0.496,-0.1,0.0889,-0.0889,0.797,0,0,-1.7,1.3
ENSMUSG00000041660,BBOX1,"butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)",cytoplasm|mitochondrion|extracellular vesicular exosome|,carnitine biosynthetic process|oxidation-reduction process|,"iron ion binding|zinc ion binding|gamma-butyrobetaine dioxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|metal ion binding|dioxygenase activity|",10,0.9,0.311,10,0.1,0.368,0.1,0.0884,0.0884,0.798,0,0,-0.8,2
ENSMUSG00000032527,PCCB,"propionyl Coenzyme A carboxylase, beta polypeptide",mitochondrion|,None,nucleotide binding|propionyl-CoA carboxylase activity|ATP binding|ligase activity|,10,0,0,10,0.1,0.344,0.1,0.086,0.086,0.799,0,0,-1.4,1.5
ENSMUSG00000032094,CD3D,"CD3 antigen, delta polypeptide",membrane|integral component of membrane|T cell receptor complex|T cell receptor complex|alpha-beta T cell receptor complex|,protein complex assembly|cell surface receptor signaling pathway|T cell activation|positive thymic T cell selection|,transmembrane signaling receptor activity|protein binding|protein heterodimerization activity|,10,0.2,0.758,10,0,0,0.1,0.0802,0.0802,0.801,0,0,-1.2,1.7
ENSMUSG00000037053,AZGP1,"alpha-2-glycoprotein 1, zinc",extracellular region|extracellular space|nucleus|membrane|MHC class I protein complex|extracellular vesicular exosome|,detection of chemical stimulus involved in sensory perception of bitter taste|positive regulation of T cell mediated cytotoxicity|antigen processing and presentation of peptide antigen via MHC class I|immune response|cell adhesion|antigen processing and presentation|regulation of multicellular organism growth|,glycoprotein binding|peptide antigen binding|,10,0,0,10,0.1,0.217,0.1,0.0784,0.0784,0.802,0,0,-1.3,1.6
ENSMUSG00000041189,CHRNB1,"cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,"postsynaptic membrane organization|skeletal muscle contraction|transport|ion transport|cation transport|cation transport|muscle contraction|signal transduction|synaptic transmission, cholinergic|neuromuscular synaptic transmission|ion transmembrane transport|ion transmembrane transport|behavioral response to nicotine|regulation of membrane potential|muscle fiber development|neurological system process|transmembrane transport|",acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|channel activity|ligand-gated ion channel activity|acetylcholine receptor activity|acetylcholine binding|,9,-1,1.87,9,0,0,0.1,0.0727,0.0727,0.804,0,0,-2,1
ENSMUSG00000054417,CYP3A44,"cytochrome P450, family 3, subfamily a, polypeptide 44",cellular_component|endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|demethylation|,monooxygenase activity|oxidoreductase activity|demethylase activity|metal ion binding|testosterone 6-beta-hydroxylase activity|,10,0.5,2.35,10,0,0,0.4,0.0723,0.0723,0.804,0,0,-0.6,2
ENSMUSG00000038357,CAMP,cathelicidin antimicrobial peptide,extracellular region|extracellular space|cytoplasm|specific granule|cell projection|extracellular vesicular exosome|,positive regulation of protein phosphorylation|innate immune response in mucosa|defense response|positive regulation of cell proliferation|antibacterial humoral response|defense response to bacterium|negative regulation of growth of symbiont in host|negative regulation of growth of symbiont on or near host surface|negative regulation of growth of symbiont on or near host surface|positive regulation of angiogenesis|defense response to Gram-negative bacterium|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|killing by host of symbiont cells|killing by host of symbiont cells|,None,10,0.2,0.53,10,-0.1,0.169,0.1,0.0709,0.0709,0.804,0,0,-1.3,1.5
ENSMUSG00000026584,SCYL3,SCY1-like 3 (S. cerevisiae),cytoplasm|Golgi apparatus|lamellipodium|cell projection|,protein phosphorylation|biological_process|,"protein kinase activity|ATP binding|transferase activity, transferring phosphorus-containing groups|",10,0.4,1.63,10,-0.2,0.555,-0.1,0.0705,-0.0705,0.805,0,0,-1.2,1.6
ENSMUSG00000046442,PPM1E,protein phosphatase 1E (PP2C domain containing),nucleus|nucleolus|cytoplasm|mitochondrion|protein complex|,negative regulation of protein kinase activity|protein dephosphorylation|cellular response to drug|peptidyl-threonine dephosphorylation|positive regulation of stress fiber assembly|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,0,0,10,-0.1,0.117,-0.1,0.0676,-0.0676,0.806,0,0,-1.5,1.5
ENSMUSG00000032047,ACAT1,acetyl-Coenzyme A acetyltransferase 1,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|extracellular vesicular exosome|,metabolic process|protein homooligomerization|,"catalytic activity|acetyl-CoA C-acetyltransferase activity|acetyl-CoA C-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|enzyme binding|protein homodimerization activity|metal ion binding|coenzyme binding|",10,0,0,10,-0.1,0.214,-0.1,0.0665,-0.0665,0.806,0,0,-1.8,1.1
ENSMUSG00000020277,PFKL,"phosphofructokinase, liver, B-type",cytoplasm|cytosol|cytosol|6-phosphofructokinase complex|membrane|extracellular vesicular exosome|,"carbohydrate metabolic process|fructose 6-phosphate metabolic process|fructose 6-phosphate metabolic process|glycolytic process|glycolytic process|metabolic process|response to glucose|response to glucose|phosphorylation|fructose 1,6-bisphosphate metabolic process|negative regulation of insulin secretion|carbohydrate phosphorylation|carbohydrate phosphorylation|protein oligomerization|protein homotetramerization|",nucleotide binding|catalytic activity|6-phosphofructokinase activity|6-phosphofructokinase activity|6-phosphofructokinase activity|ATP binding|kinase activity|transferase activity|kinase binding|identical protein binding|metal ion binding|monosaccharide binding|fructose binding|fructose-6-phosphate binding|,10,-0.7,0.27,10,-0.1,0.238,-0.1,0.0645,-0.0645,0.807,0,0,-2,1
ENSMUSG00000022490,PPP1R1A,"protein phosphatase 1, regulatory (inhibitor) subunit 1A",extracellular space|cytoplasm|,carbohydrate metabolic process|glycogen metabolic process|signal transduction|,protein phosphatase inhibitor activity|protein binding|,10,0.1,0.292,10,-0.1,0.119,0.1,0.0638,0.0638,0.807,0,0,-1.3,1.6
ENSMUSG00000028078,DCLK2,doublecortin-like kinase 2,cytoplasm|cytoskeleton|,protein phosphorylation|phosphorylation|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.3,0.762,10,0.2,0.382,0.1,0.0611,0.0611,0.808,0,0,-1.5,1.5
ENSMUSG00000078931,PDF,peptide deformylase (mitochondrial),mitochondrion|,positive regulation of cell proliferation|peptidyl-methionine modification|N-terminal protein amino acid modification|,peptide deformylase activity|,10,0.4,1.3,10,-0.7,2.71,-0.4,0.0572,-0.0572,0.81,0,0,-2,0.9
ENSMUSG00000027805,PFN2,profilin 2,cytoplasm|cytoskeleton|terminal bouton|extracellular vesicular exosome|,negative regulation of epithelial cell migration|negative regulation of epithelial cell migration|actin cytoskeleton organization|negative regulation of actin filament polymerization|negative regulation of actin filament polymerization|positive regulation of actin filament polymerization|positive regulation of actin filament polymerization|positive regulation of actin filament bundle assembly|positive regulation of ATPase activity|positive regulation of peptidyl-serine phosphorylation|positive regulation of peptidyl-serine phosphorylation|positive regulation of stress fiber assembly|positive regulation of stress fiber assembly|negative regulation of ruffle assembly|negative regulation of ruffle assembly|regulation of synaptic vesicle exocytosis|,"adenyl-nucleotide exchange factor activity|actin binding|actin monomer binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|",10,0.2,0.232,10,-0.1,0.127,-0.1,0.0557,-0.0557,0.811,0,0,-1.5,1.4
ENSMUSG00000024942,CAPN1,calpain 1,intracellular|cytoplasm|cytoplasm|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,proteolysis|proteolysis|proteolysis|protein autoprocessing|receptor catabolic process|,calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|protein binding|cytoskeletal protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|,10,0.1,0.122,10,-0.3,0.965,-0.1,0.0544,-0.0544,0.811,0,0,-1.8,1
ENSMUSG00000027984,HADH,hydroxyacyl-Coenzyme A dehydrogenase,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|response to activity|response to drug|negative regulation of insulin secretion|oxidation-reduction process|,"3-hydroxyacyl-CoA dehydrogenase activity|3-hydroxyacyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|coenzyme binding|NAD+ binding|",10,0.2,0.718,10,-0.1,0.0982,-0.1,0.052,-0.052,0.812,0,0,-1.4,1.4
ENSMUSG00000029269,SULT1B1,"sulfotransferase family 1B, member 1",cytoplasm|cytosol|,lipid metabolic process|xenobiotic metabolic process|steroid metabolic process|flavonoid metabolic process|phenol-containing compound metabolic process|thyroid hormone metabolic process|sulfation|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|aryl sulfotransferase activity|aryl sulfotransferase activity|aryl sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0,0,10,0.1,0.0521,0.1,0.0406,0.0406,0.817,0,0,-1.5,1.4
ENSMUSG00000074890,LCMT2,leucine carboxyl methyltransferase 2,cellular_component|,C-terminal protein methylation|tRNA processing|methylation|,protein C-terminal carboxyl O-methyltransferase activity|methyltransferase activity|transferase activity|,10,0.3,1.03,10,-0.1,0.000828,0.1,0.0386,0.0386,0.818,0,0,-1.4,1.4
ENSMUSG00000046854,PIP5KL1,phosphatidylinositol-4-phosphate 5-kinase-like 1,cytoplasm|membrane|cell projection|,phosphorylation|phosphatidylinositol metabolic process|phosphatidylinositol phosphorylation|,nucleotide binding|protein binding|ATP binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|transferase activity|,10,0.2,0.619,10,0,0,-0.1,0.0344,-0.0344,0.819,0,0,-1.4,1.4
ENSMUSG00000029212,GABRB1,"gamma-aminobutyric acid (GABA) A receptor, subunit beta 1",nucleus|nuclear envelope|cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|dendrite|chloride channel complex|receptor complex|synapse|postsynaptic membrane|GABA-A receptor complex|,transport|ion transport|ion transport|anion transport|chloride transport|signal transduction|response to toxic substance|ion transmembrane transport|cellular response to histamine|,GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|anion channel activity|chloride channel activity|ligand-gated ion channel activity|GABA receptor binding|,10,0,0,9,0.1,0.589,0.1,0.0278,0.0278,0.822,0,0,-1.5,1.5
ENSMUSG00000005339,FCER1A,"Fc receptor, IgE, high affinity I, alpha polypeptide",cell|plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|membrane raft|,activation of MAPK activity|positive regulation of type I hypersensitivity|serotonin secretion|serotonin secretion|signal transduction|cell surface receptor signaling pathway|cell surface receptor signaling pathway|activation of JUN kinase activity|leukotriene biosynthetic process|Fc-epsilon receptor signaling pathway|positive regulation of mast cell degranulation|positive regulation of interleukin-3 biosynthetic process|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of calcium-mediated signaling|,protein binding|IgE receptor activity|IgE receptor activity|IgE binding|IgE binding|,10,1.1,1.45,10,0.1,0.0485,0.1,0.0255,0.0255,0.823,0,0,-0.8,2
ENSMUSG00000074604,MGST2,microsomal glutathione S-transferase 2,nuclear envelope|cytoplasm|endoplasmic reticulum|plasma membrane|intracellular membrane-bounded organelle|,glutathione biosynthetic process|leukotriene biosynthetic process|leukotriene biosynthetic process|oxidation-reduction process|oxidation-reduction process|,glutathione transferase activity|glutathione transferase activity|leukotriene-C4 synthase activity|leukotriene-C4 synthase activity|glutathione peroxidase activity|glutathione peroxidase activity|transferase activity|,10,0.4,0.0453,10,0.1,0.31,0.1,0.0222,0.0222,0.824,0,0,-1,1.9
ENSMUSG00000034744,NAGK,N-acetylglucosamine kinase,extracellular vesicular exosome|,N-acetylglucosamine metabolic process|phosphorylation|N-acetylneuraminate catabolic process|carbohydrate phosphorylation|carbohydrate phosphorylation|,nucleotide binding|ATP binding|N-acylmannosamine kinase activity|kinase activity|transferase activity|N-acetylglucosamine kinase activity|N-acetylglucosamine kinase activity|,10,0.1,0.138,10,-0.3,0.0493,0.1,0.0221,0.0221,0.824,0,0,-1.5,1.4
ENSMUSG00000005951,SHPK,sedoheptulokinase,cytoplasm|,"carbohydrate metabolic process|carbohydrate metabolic process|pentose-phosphate shunt, non-oxidative branch|phosphorylation|phosphorylation|cellular response to interleukin-13|regulation of macrophage activation|regulation of inflammatory response|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|cellular response to interleukin-4|","nucleotide binding|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|sedoheptulokinase activity|sedoheptulokinase activity|",10,0,0,10,0.1,0.083,0.1,0.02,0.02,0.825,0,0,-1.5,1.4
ENSMUSG00000025477,INPP5A,inositol polyphosphate-5-phosphatase A,membrane|extracellular vesicular exosome|,inositol phosphate dephosphorylation|,inositol-polyphosphate 5-phosphatase activity|PH domain binding|,10,-0.1,0.0428,10,1.4,1.67,0.1,0.018,0.018,0.825,0,0,-0.9,3
ENSMUSG00000031284,PAK3,p21 protein (Cdc42/Rac)-activated kinase 3,cytoplasm|endosome|,MAPK cascade|activation of MAPK activity|protein phosphorylation|protein phosphorylation|multicellular organismal development|axonogenesis|metabolic process|regulation of neuron projection development|phosphorylation|dendrite development|signal transduction by phosphorylation|regulation of actin filament polymerization|positive regulation of neuron apoptotic process|positive regulation of dendritic spine morphogenesis|positive regulation of DNA biosynthetic process|,"nucleotide binding|catalytic activity|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rho GTPase binding|SH3 domain binding|metal ion binding|GTPase binding|",10,0.1,0.182,10,-0.1,0.0261,-0.1,0.0172,-0.0172,0.826,0,0,-1.4,1.6
ENSMUSG00000032359,CTSH,cathepsin H,outer dense fiber|acrosomal vesicle|extracellular space|lysosome|cytosol|axoneme|extracellular vesicular exosome|alveolar lamellar body|,T cell mediated cytotoxicity|immune response-regulating signaling pathway|proteolysis|proteolysis|proteolysis|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of epithelial cell migration|neuropeptide catabolic process|bradykinin catabolic process|positive regulation of peptidase activity|positive regulation of peptidase activity|positive regulation of cell migration|zymogen activation|zymogen activation|protein destabilization|protein destabilization|response to retinoic acid|membrane protein proteolysis|membrane protein proteolysis|negative regulation of apoptotic process|surfactant homeostasis|positive regulation of angiogenesis|dichotomous subdivision of terminal units involved in lung branching|ERK1 and ERK2 cascade|positive regulation of apoptotic signaling pathway|,endopeptidase activity|endopeptidase activity|aminopeptidase activity|cysteine-type endopeptidase activity|cysteine-type endopeptidase activity|serine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|cysteine-type endopeptidase activator activity involved in apoptotic process|cysteine-type endopeptidase activator activity involved in apoptotic process|peptidase activator activity involved in apoptotic process|hydrolase activity|HLA-A specific activating MHC class I receptor activity|kininogen binding|protein complex binding|protein self-association|thyroid hormone binding|,10,0.1,0.108,10,-0.1,0.055,0.1,0.00649,0.00649,0.83,0,0,-1.4,1.6
ENSMUSG00000000253,GMPR,guanosine monophosphate reductase,cellular_component|GMP reductase complex|,purine nucleobase metabolic process|nucleotide metabolic process|oxidation-reduction process|,catalytic activity|GMP reductase activity|oxidoreductase activity|metal ion binding|,10,0.2,0.1,10,0,0,0.1,0.00451,0.00451,0.831,0,0,-1,1.9
ENSMUSG00000036353,P2RY12,"purinergic receptor P2Y, G-protein coupled 12",mitochondrion|plasma membrane|integral component of plasma membrane|caveola|external side of plasma membrane|basal plasma membrane|membrane|integral component of membrane|intrinsic component of membrane|,adenosine receptor signaling pathway|adenosine receptor signaling pathway|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|blood coagulation|glial cell migration|negative regulation of norepinephrine secretion|cell projection organization|platelet activation|G-protein coupled purinergic nucleotide receptor signaling pathway|G-protein coupled purinergic nucleotide receptor signaling pathway|positive regulation of ion transport|protein kinase B signaling|negative regulation of cell differentiation|regulation of calcium ion transport|platelet aggregation|calcium ion transmembrane transport|potassium ion transmembrane transport|,G-protein coupled adenosine receptor activity|ADP receptor activity|ADP receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled purinergic nucleotide receptor activity|,10,-0.1,0.126,10,1.1,1.1,-0.1,0.00159,-0.00159,0.832,0,0,-0.9,2
ENSMUSG00000041548,HSPB8,heat shock protein 8,intracellular|nucleus|cytoplasm|,response to stress|,protein binding|identical protein binding|,10,0,0,10,-0.5,1.04,-0.1,0.00117,-0.00117,0.832,0,0,-1.2,2
ENSMUSG00000045730,ADRB2,"adrenergic receptor, beta 2",nucleus|nucleus|cytoplasm|endosome|plasma membrane|integral component of plasma membrane|caveola|membrane|membrane|integral component of membrane|apical plasma membrane|axon|dendrite|neuronal cell body membrane|sarcolemma|dendritic spine|intracellular membrane-bounded organelle|receptor complex|,"regulation of systemic arterial blood pressure by norepinephrine-epinephrine|diet induced thermogenesis|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|regulation of sodium ion transport|desensitization of G-protein coupled receptor protein signaling pathway by arrestin|diaphragm contraction|positive regulation of the force of heart contraction by epinephrine|receptor-mediated endocytosis|regulation of smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|positive regulation of cell proliferation|associative learning|response to cold|positive regulation of sodium ion transport|negative regulation of angiogenesis|negative regulation of ossification|positive regulation of bone mineralization|positive regulation of protein ubiquitination|heat generation|positive regulation of ATPase activity|synaptic transmission, glutamatergic|negative regulation of urine volume|negative regulation of multicellular organism growth|wound healing|regulation of vasodilation|positive regulation of apoptotic process|positive regulation of potassium ion transport|positive regulation of MAPK cascade|bone resorption|positive regulation of heart contraction|positive regulation of vasodilation|positive regulation of transcription from RNA polymerase II promoter|negative regulation of smooth muscle contraction|positive regulation of skeletal muscle tissue growth|negative regulation of inflammatory response|brown fat cell differentiation|regulation of calcium ion transport|regulation of sensory perception of pain|regulation of excitatory postsynaptic membrane potential|cellular response to hypoxia|adrenergic receptor signaling pathway|adrenergic receptor signaling pathway|negative regulation of platelet aggregation|",G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|beta2-adrenergic receptor activity|beta2-adrenergic receptor activity|protein binding|drug binding|adenylate cyclase binding|potassium channel regulator activity|enzyme binding|B2 bradykinin receptor binding|protein complex binding|dopamine binding|ionotropic glutamate receptor binding|protein homodimerization activity|epinephrine binding|norepinephrine binding|,10,0,0,10,1.3,0.672,0,0,0,0.832,0,0,-0.9,2
ENSMUSG00000047205,DUSP18,dual specificity phosphatase 18,nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|mitochondrial intermembrane space|membrane|intrinsic component of mitochondrial inner membrane|extrinsic component of mitochondrial inner membrane|extrinsic component of mitochondrial inner membrane|,protein dephosphorylation|protein targeting to membrane|protein targeting to mitochondrion|dephosphorylation|protein localization to organelle|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|response to antibiotic|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,10,-0.2,0.679,10,0.2,0.393,0,0,0,0.832,0,0,-1.5,1.4
ENSMUSG00000021765,FST,follistatin,extracellular region|nucleus|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|skeletal system development|hematopoietic progenitor cell differentiation|gamete generation|pattern specification process|female gonad development|BMP signaling pathway|hair follicle morphogenesis|negative regulation of activin receptor signaling pathway|odontogenesis of dentin-containing tooth|keratinocyte proliferation|negative regulation of cell differentiation|negative regulation of cell differentiation|positive regulation of hair follicle development|,heparan sulfate proteoglycan binding|activin binding|,9,0,0,9,0.1,0.048,0,0,0,0.832,0,0,-0.9,2
ENSMUSG00000005800,MMP8,matrix metallopeptidase 8,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|,proteolysis|collagen catabolic process|,metalloendopeptidase activity|serine-type endopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.1,0.00451,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000005268,PRLR,prolactin receptor,intracellular|cell surface|membrane|integral component of membrane|,activation of transmembrane receptor protein tyrosine kinase activity|JAK-STAT cascade|lactation|lactation|regulation of cell adhesion|regulation of epithelial cell differentiation|prolactin signaling pathway|prolactin signaling pathway|mammary gland epithelial cell differentiation|prostate gland growth|mammary gland alveolus development|mammary gland alveolus development|mammary gland epithelium development|,cytokine receptor activity|prolactin receptor activity|prolactin receptor activity|prolactin receptor activity|protein binding|peptide hormone binding|protein kinase binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000031173,OTC,ornithine transcarbamylase,cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|,urea cycle|cellular amino acid metabolic process|arginine biosynthetic process|ornithine metabolic process|ornithine catabolic process|cellular amino acid biosynthetic process|citrulline biosynthetic process|anion homeostasis|protein homotrimerization|ammonia homeostasis|,ornithine carbamoyltransferase activity|phospholipid binding|amino acid binding|transferase activity|carboxyl- or carbamoyltransferase activity|phosphate ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000005397,NID1,nidogen 1,extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basement membrane|basement membrane|basal lamina|extracellular matrix|extracellular vesicular exosome|cell periphery|,cell adhesion|cell-matrix adhesion|positive regulation of cell-substrate adhesion|extracellular matrix organization|glomerular basement membrane development|,calcium ion binding|protein binding|collagen binding|collagen binding|laminin binding|laminin-1 binding|proteoglycan binding|extracellular matrix binding|,10,0.1,0.0355,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000033278,PTPRM,"protein tyrosine phosphatase, receptor type, M",cytoplasm|cell-cell junction|cell-cell adherens junction|membrane|integral component of membrane|lamellipodium|perinuclear region of cytoplasm|,negative regulation of endothelial cell proliferation|protein dephosphorylation|cell adhesion|homophilic cell adhesion|signal transduction|negative regulation of endothelial cell migration|retina layer formation|dephosphorylation|negative regulation of angiogenesis|neuron projection development|retinal ganglion cell axon guidance|peptidyl-tyrosine dephosphorylation|response to drug|positive regulation of vasodilation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|transmembrane receptor protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|identical protein binding|cadherin binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000025068,GSTO1,glutathione S-transferase omega 1,basement membrane|cytoplasm|cytosol|axon|nuclear membrane|myelin sheath|cell body|extracellular vesicular exosome|,metabolic process|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|L-ascorbic acid metabolic process|L-ascorbic acid biosynthetic process|xenobiotic catabolic process|oxidation-reduction process|negative regulation of ryanodine-sensitive calcium-release channel activity|positive regulation of ryanodine-sensitive calcium-release channel activity|cellular response to arsenic-containing substance|,glutathione transferase activity|oxidoreductase activity|transferase activity|glutathione dehydrogenase (ascorbate) activity|methylarsonate reductase activity|,10,0.1,0.136,10,-0.1,0.594,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000061578,KSR2,kinase suppressor of ras 2,intracellular|cytoplasm|cytosol|plasma membrane|membrane|,protein phosphorylation|phosphorylation|calcium-mediated signaling|intracellular signal transduction|positive regulation of MAPK cascade|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP-kinase scaffold activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase binding|metal ion binding|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.3,1.8
ENSMUSG00000046733,GPRC5A,"G protein-coupled receptor, family C, group 5, member A",plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000022793,B4GALT4,"UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4",cellular_component|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|N-acetyllactosamine synthase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,1.1,2.25,10,0,0,0,0,0,0.832,0,0,-0.8,2
ENSMUSG00000027612,MMP24,matrix metallopeptidase 24,extracellular region|proteinaceous extracellular matrix|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular matrix|extracellular vesicular exosome|,proteolysis|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.352,10,-0.2,0.802,0,0,0,0.832,0,0,-1.8,1.1
ENSMUSG00000040016,PTGER3,prostaglandin E receptor 3 (subtype EP3),plasma membrane|membrane|integral component of membrane|,fever generation|fever generation|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|bicarbonate transport|positive regulation of fever generation|response to lipopolysaccharide|positive regulation of urine volume|,signal transducer activity|G-protein coupled receptor activity|prostaglandin receptor activity|prostaglandin E receptor activity|prostaglandin E receptor activity|protein binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000024588,FECH,ferrochelatase,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,porphyrin-containing compound biosynthetic process|heme biosynthetic process|heme biosynthetic process|heme biosynthetic process|heme biosynthetic process|cholesterol metabolic process|response to light stimulus|detection of UV|regulation of gene expression|regulation of eIF2 alpha phosphorylation by heme|regulation of eIF2 alpha phosphorylation by heme|erythrocyte differentiation|very-low-density lipoprotein particle assembly|protoporphyrinogen IX metabolic process|protoporphyrinogen IX metabolic process|regulation of hemoglobin biosynthetic process|iron ion homeostasis|,"ferrochelatase activity|ferrochelatase activity|ferrochelatase activity|iron ion binding|lyase activity|heme binding|iron-responsive element binding|metal ion binding|tetrapyrrole binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000068335,DOK1,docking protein 1,intracellular|nucleus|cytoplasm|,MAPK cascade|transmembrane receptor protein tyrosine kinase signaling pathway|Ras protein signal transduction|intracellular signal transduction|,receptor signaling protein activity|insulin receptor binding|protein binding|,10,-0.1,0.0633,10,0.2,0.274,0,0,0,0.832,0,0,-0.8,2
ENSMUSG00000028972,CAR6,carbonic anhydrase 6,extracellular region|extracellular space|extracellular space|cytoplasm|extracellular vesicular exosome|,detection of chemical stimulus involved in sensory perception of bitter taste|one-carbon metabolic process|,molecular_function|carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,0.4,1.51,10,-0.1,0.315,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000021768,DUSP13,dual specificity phosphatase 13,cytoplasm|,protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,-0.2,0.697,10,0.1,0.177,0,0,0,0.832,0,0,-1.7,1.2
ENSMUSG00000052854,NRK,Nik related kinase,None,protein phosphorylation|activation of JNKK activity|parturition|negative regulation of cell proliferation|phosphorylation|signal transduction by phosphorylation|intracellular signal transduction|regulation of spongiotrophoblast cell proliferation|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,2.3,10,0,0,0,0,0,0.832,0,0,-0.9,1.8
ENSMUSG00000023328,ACHE,acetylcholinesterase,extracellular region|basal lamina|extracellular space|nuclear envelope|cytoplasm|endoplasmic reticulum lumen|endoplasmic reticulum lumen|rough endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|cell surface|cell surface|membrane|cell junction|axon|axon|dendrite|dendrite|anchored component of membrane|neuromuscular junction|presynaptic membrane|presynaptic membrane|neuron projection|neuronal cell body|synapse|synapse|postsynaptic membrane|postsynaptic membrane|perinuclear region of cytoplasm|,"regulation of receptor recycling|acetylcholine catabolic process|acetylcholine catabolic process|cell adhesion|synaptic transmission, cholinergic|synapse assembly|synapse assembly|acetylcholine metabolic process|choline metabolic process|choline metabolic process|receptor internalization|neurotransmitter catabolic process|neurotransmitter receptor biosynthetic process|regulation of dendrite morphogenesis|regulation of axonogenesis|positive regulation of axonogenesis|positive regulation of dendrite morphogenesis|protein tetramerization|retina development in camera-type eye|neuron death|",acetylcholinesterase activity|acetylcholinesterase activity|cholinesterase activity|cholinesterase activity|collagen binding|hydrolase activity|serine hydrolase activity|choline binding|acetylcholine binding|protein homodimerization activity|laminin binding|laminin binding|protein self-association|carboxylic ester hydrolase activity|,10,-0.3,0.0191,10,0,0,0,0,0,0.832,0,0,-1.9,1.1
ENSMUSG00000000409,LCK,lymphocyte protein tyrosine kinase,pericentriolar material|immunological synapse|intracellular|cell|cytoplasm|plasma membrane|cell-cell junction|membrane|endocytic vesicle|membrane raft|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell surface receptor signaling pathway|response to mechanical stimulus|response to metal ion|positive regulation of gene expression|phosphorylation|dephosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|T cell differentiation|response to drug|positive regulation of tyrosine phosphorylation of Stat5 protein|response to hydrogen peroxide|positive regulation of gamma-delta T cell differentiation|protein autophosphorylation|protein autophosphorylation|B cell receptor signaling pathway|regulation of T cell receptor signaling pathway|positive regulation of T cell activation|release of sequestered calcium ion into cytosol|positive regulation of uterine smooth muscle contraction|positive regulation of intrinsic apoptotic signaling pathway|,"nucleotide binding|glycoprotein binding|antigen binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein serine/threonine phosphatase activity|protein binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein phosphatase binding|protein complex binding|SH2 domain binding|CD4 receptor binding|CD8 receptor binding|identical protein binding|phosphatidylinositol 3-kinase binding|ATPase binding|",10,0.2,0.348,10,1.1,0.709,0,0,0,0.832,0,0,-0.9,2
ENSMUSG00000031027,STK33,serine/threonine kinase 33,cytoplasm|,protein phosphorylation|phosphorylation|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.4,0.83,0,0,0,0.832,0,0,-1.1,1.8
ENSMUSG00000031373,CAR5B,"carbonic anhydrase 5b, mitochondrial",mitochondrion|,one-carbon metabolic process|,carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,-0.2,0.233,10,0,0,0,0,0,0.832,0,0,-1.8,1.1
ENSMUSG00000039936,PIK3CD,phosphatidylinositol 3-kinase catalytic delta polypeptide,cytoplasm|plasma membrane|phosphatidylinositol 3-kinase complex|,B cell homeostasis|immune system process|chemotaxis|inflammatory response|cell surface receptor signaling pathway|phosphorylation|cell differentiation|phosphatidylinositol-3-phosphate biosynthetic process|B cell activation|innate immune response|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|,"nucleotide binding|protein binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|1-phosphatidylinositol-4-phosphate 3-kinase activity|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|",10,0.2,1.02,10,0,0,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000007653,GABRB2,"gamma-aminobutyric acid (GABA) A receptor, subunit beta 2",cytosol|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|extracellular vesicular exosome|GABA-A receptor complex|,"transport|ion transport|chloride transport|signal transduction|sensory perception of sound|ion transmembrane transport|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|neuron development|synaptic transmission, GABAergic|inner ear receptor cell development|innervation|cellular response to histamine|cochlea development|negative regulation of neuron death|chloride transmembrane transport|",GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|inhibitory extracellular ligand-gated ion channel activity|chloride channel activity|chloride channel activity|protein binding|,9,0,0,9,0.3,0.998,0,0,0,0.832,0,0,-1.2,1.8
ENSMUSG00000021959,LATS2,large tumor suppressor 2,spindle pole|spindle pole|intracellular|nucleus|cytoplasm|cytoskeleton|,G1/S transition of mitotic cell cycle|G1/S transition of mitotic cell cycle|protein phosphorylation|protein phosphorylation|cell cycle|mitotic nuclear division|hormone-mediated signaling pathway|phosphorylation|keratinocyte differentiation|cellular protein localization|cellular protein localization|hippo signaling|hippo signaling|intracellular signal transduction|negative regulation of cyclin-dependent protein serine/threonine kinase activity|regulation of organ growth|cell division|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.2,0.639,10,0,0,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000028551,CDKN2C,"cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)",nucleus|cytoplasm|,regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|cell cycle|cell cycle arrest|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell growth|negative regulation of phosphorylation|negative regulation of protein serine/threonine kinase activity|,cyclin-dependent protein serine/threonine kinase inhibitor activity|protein kinase binding|,9,0.2,0.45,9,-0.1,0.164,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000031700,GPT2,glutamic pyruvate transaminase (alanine aminotransferase) 2,mitochondrion|,2-oxoglutarate metabolic process|biosynthetic process|L-alanine metabolic process|,catalytic activity|L-alanine:2-oxoglutarate aminotransferase activity|transaminase activity|transferase activity|pyridoxal phosphate binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.4,1.8
ENSMUSG00000061780,CFD,complement factor D (adipsin),extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|,"immune system process|proteolysis|complement activation, alternative pathway|Notch signaling pathway|innate immune response|",catalytic activity|endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.1,0.159,0,0,0,0.832,0,0,-1.8,1.1
ENSMUSG00000026204,PTPRN,"protein tyrosine phosphatase, receptor type, N",plasma membrane|membrane|membrane|integral component of membrane|,response to reactive oxygen species|protein dephosphorylation|transmembrane receptor protein tyrosine phosphatase signaling pathway|dephosphorylation|cytokine-mediated signaling pathway|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|spectrin binding|GTPase binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.1,1.9
ENSMUSG00000005958,EPHB3,Eph receptor B3,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell projection|,angiogenesis|urogenital system development|protein phosphorylation|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|axon guidance|axon guidance|axonal fasciculation|phosphorylation|cell migration|cell migration|peptidyl-tyrosine phosphorylation|central nervous system projection neuron axonogenesis|corpus callosum development|regulation of cell-cell adhesion|retinal ganglion cell axon guidance|regulation of Rac GTPase activity|substrate adhesion-dependent cell spreading|regulation of Cdc42 GTPase activity|protein autophosphorylation|ephrin receptor signaling pathway|ephrin receptor signaling pathway|thymus development|digestive tract morphogenesis|regulation of axonogenesis|positive regulation of synapse assembly|palate development|dendritic spine development|dendritic spine morphogenesis|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|transmembrane-ephrin receptor activity|ATP binding|axon guidance receptor activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-0.2,0.238,0,0,0,0.832,0,0,-1.9,1
ENSMUSG00000046402,RBP1,"retinol binding protein 1, cellular",cytoplasm|cytosol|cell body|,transport|regulation of granulocyte differentiation|response to vitamin A|retinol metabolic process|retinol metabolic process|retinol metabolic process|retinoic acid metabolic process|retinoic acid metabolic process|,transporter activity|retinoid binding|lipid binding|retinal binding|retinol binding|,10,0.1,0.087,10,0,0,0,0,0,0.832,0,0,-1.8,1.1
ENSMUSG00000002033,CD3G,"CD3 antigen, gamma polypeptide",membrane|integral component of membrane|alpha-beta T cell receptor complex|,establishment or maintenance of cell polarity|cell surface receptor signaling pathway|protein transport|regulation of lymphocyte apoptotic process|,transmembrane signaling receptor activity|protein binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000058709,EGLN2,egl-9 family hypoxia-inducible factor 2,nucleus|cytosol|,response to hypoxia|peptidyl-proline hydroxylation to 4-hydroxy-L-proline|regulation of neuron apoptotic process|cell redox homeostasis|positive regulation of protein catabolic process|oxidation-reduction process|,"iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|oxygen sensor activity|L-ascorbic acid binding|peptidyl-proline dioxygenase activity|peptidyl-proline 4-dioxygenase activity|metal ion binding|dioxygenase activity|",10,0,0,10,-0.1,0.0388,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000026384,PTPN4,"protein tyrosine phosphatase, non-receptor type 4",cytoplasm|cytoskeleton|plasma membrane|cytoplasmic side of plasma membrane|membrane|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|non-membrane spanning protein tyrosine phosphatase activity|protein binding|cytoskeletal protein binding|hydrolase activity|phosphatase activity|,10,-0.1,0.159,10,0.1,0.187,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000049511,HTR1B,5-hydroxytryptamine (serotonin) receptor 1B,cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,"G-protein coupled receptor internalization|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting serotonin receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|serotonin receptor signaling pathway|synaptic transmission|behavior|feeding behavior|response to toxic substance|regulation of dopamine secretion|negative regulation of serotonin secretion|negative regulation of cAMP biosynthetic process|negative regulation of cAMP biosynthetic process|negative regulation of synaptic transmission, GABAergic|cellular response to drug|response to cocaine|vasoconstriction|response to drug|drinking behavior|response to ethanol|bone remodeling|regulation of behavior|negative regulation of synaptic transmission, glutamatergic|cellular response to alkaloid|cellular response to temperature stimulus|",signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|serotonin receptor activity|drug binding|drug binding|serotonin binding|serotonin binding|,10,0,0,10,-0.1,0.139,0,0,0,0.832,0,0,-1.8,1.1
ENSMUSG00000029859,EPHA1,Eph receptor A1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,angiogenesis|positive regulation of cell-matrix adhesion|protein phosphorylation|negative regulation of protein kinase activity|cell adhesion|cell surface receptor signaling pathway|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of cell proliferation|phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of cell migration|negative regulation of cell migration|regulation of Rac GTPase activity|activation of Rho GTPase activity|substrate adhesion-dependent cell spreading|positive regulation of angiogenesis|protein autophosphorylation|ephrin receptor signaling pathway|positive regulation of stress fiber assembly|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|transmembrane-ephrin receptor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|",10,0.2,0.743,10,0,0,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000025575,CANT1,calcium activated nucleotidase 1,endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|ribonucleoside diphosphate catabolic process|proteoglycan biosynthetic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|,guanosine-diphosphatase activity|signal transducer activity|calcium ion binding|pyrophosphatase activity|hydrolase activity|nucleoside-diphosphatase activity|uridine-diphosphatase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000003031,CDKN1B,cyclin-dependent kinase inhibitor 1B,nucleus|nucleus|cytoplasm|cytoplasm|endosome|cytosol|protein complex|,"G1/S transition of mitotic cell cycle|G1/S transition of mitotic cell cycle|potassium ion transport|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell cycle|cell cycle arrest|cell cycle arrest|sensory perception of sound|cell death|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of cell death|negative regulation of cell growth|positive regulation of microtubule polymerization|negative regulation of kinase activity|negative regulation of phosphorylation|negative regulation of apoptotic process|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|autophagic cell death|inner ear development|negative regulation of epithelial cell proliferation|negative regulation of cellular component movement|negative regulation of epithelial cell proliferation involved in prostate gland development|cellular response to antibiotic|cellular response to lithium ion|cellular response to organic cyclic compound|mitotic cell cycle arrest|",protein kinase inhibitor activity|cyclin-dependent protein serine/threonine kinase inhibitor activity|protein binding|cysteine-type endopeptidase activator activity involved in apoptotic process|protein phosphatase binding|Hsp70 protein binding|protein complex binding|chaperone binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.8,1.3
ENSMUSG00000011877,GIT1,G protein-coupled receptor kinase-interactor 1,cytoplasm|focal adhesion|membrane|aggresome|,regulation of G-protein coupled receptor protein signaling pathway|regulation of ARF GTPase activity|positive regulation of GTPase activity|,GTPase activator activity|protein binding|ARF GTPase activator activity|zinc ion binding|small GTPase binding|protein homodimerization activity|metal ion binding|,10,0.1,0.233,10,0,0,0,0,0,0.832,0,0,-1.2,1.8
ENSMUSG00000040479,DGKZ,diacylglycerol kinase zeta,nucleus|cytoplasm|plasma membrane|membrane|lamellipodium|,protein kinase C-activating G-protein coupled receptor signaling pathway|metabolic process|phosphorylation|mitotic G1 DNA damage checkpoint|intracellular signal transduction|negative regulation of catalytic activity|negative regulation of mitotic cell cycle|negative regulation of Ras protein signal transduction|lipid phosphorylation|,nucleotide binding|lipid kinase activity|NAD+ kinase activity|diacylglycerol kinase activity|enzyme inhibitor activity|protein binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|metal ion binding|,10,0,0,10,-1.2,1.96,0,0,0,0.832,0,0,-2,0.7
ENSMUSG00000036760,KCNK9,"potassium channel, subfamily K, member 9",plasma membrane|synaptic vesicle|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|potassium channel activity|protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000042265,TREM1,triggering receptor expressed on myeloid cells 1,cell|membrane|integral component of membrane|,cytokine secretion involved in immune response|cell migration|neutrophil chemotaxis|cytokine metabolic process|chemokine metabolic process|neutrophil mediated killing of gram-negative bacterium|neutrophil extravasation|,scaffold protein binding|,10,-0.1,0.24,10,0.1,0.0207,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000031343,GABRA3,"gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3",plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|signal transduction|gamma-aminobutyric acid signaling pathway|synaptic transmission|,GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|chloride channel activity|,10,-0.1,0.162,10,0,0,0,0,0,0.832,0,0,-1.2,1.9
ENSMUSG00000026817,AK1,adenylate kinase 1,outer dense fiber|cytoplasm|cytoplasm|plasma membrane|sarcomere|sperm flagellum|neuron projection|perinuclear region of cytoplasm|extracellular vesicular exosome|,nucleobase-containing compound metabolic process|nucleoside diphosphate phosphorylation|ADP biosynthetic process|cell cycle arrest|nucleoside triphosphate biosynthetic process|positive regulation of glucose transport|phosphorylation|AMP metabolic process|ATP metabolic process|inosine biosynthetic process|nucleotide phosphorylation|,"nucleotide binding|adenylate kinase activity|adenylate kinase activity|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, phosphate group as acceptor|nucleobase-containing compound kinase activity|",9,-0.1,0.21,9,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000018648,DUSP14,dual specificity phosphatase 14,nucleus|cytoplasm|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|poly(A) RNA binding|,10,0.3,0.71,10,0,0,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000047409,CTDSPL,"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like",nucleus|extracellular vesicular exosome|,negative regulation of protein phosphorylation|negative regulation of G1/S transition of mitotic cell cycle|,molecular_function|phosphoprotein phosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.1,1.9
ENSMUSG00000046159,CHRM3,"cholinergic receptor, muscarinic 3, cardiac",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|dendrite|asymmetric synapse|axon terminus|synapse|postsynaptic membrane|,"regulation of vascular smooth muscle contraction|smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway|G-protein coupled acetylcholine receptor signaling pathway|G-protein coupled acetylcholine receptor signaling pathway|synaptic transmission|synaptic transmission, cholinergic|digestion|regulation of vasoconstriction|positive regulation of smooth muscle contraction|positive regulation of smooth muscle contraction|saliva secretion|",signal transducer activity|G-protein coupled receptor activity|drug binding|acetylcholine receptor activity|G-protein coupled acetylcholine receptor activity|acetylcholine binding|,10,0.2,0.485,10,-0.3,0.0203,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000022044,STMN4,stathmin-like 4,cellular_component|Golgi apparatus|cell projection|,biological_process|regulation of microtubule polymerization or depolymerization|,molecular_function|,10,-0.1,0.0919,10,1.5,1.12,0,0,0,0.832,0,0,-0.8,3
ENSMUSG00000021622,CKMT2,"creatine kinase, mitochondrial 2",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,phosphocreatine metabolic process|phosphorylation|,"nucleotide binding|catalytic activity|creatine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-0.1,0.0697,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000035824,TK2,"thymidine kinase 2, mitochondrial",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|,nucleobase-containing compound metabolic process|DNA replication|mitochondrial DNA replication|deoxyribonucleoside monophosphate biosynthetic process|deoxyribonucleoside monophosphate biosynthetic process|nucleotide biosynthetic process|deoxyribonucleotide metabolic process|phosphorylation|mitochondrial DNA metabolic process|deoxycytidine metabolic process|thymidine metabolic process|,nucleotide binding|deoxycytidine kinase activity|thymidine kinase activity|thymidine kinase activity|ATP binding|kinase activity|transferase activity|nucleoside kinase activity|,10,0.1,0.0873,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000032648,PYGM,muscle glycogen phosphorylase,cytoplasm|sarcoplasmic reticulum|Z disc|,response to hypoxia|carbohydrate metabolic process|glycogen metabolic process|glycogen catabolic process|glycogen catabolic process|glycogen catabolic process|cellular calcium ion homeostasis|metabolic process|response to organic substance|response to cAMP|,"nucleotide binding|catalytic activity|phosphorylase activity|drug binding|glycogen phosphorylase activity|glycogen phosphorylase activity|glycogen phosphorylase activity|AMP binding|transferase activity|transferase activity, transferring glycosyl groups|pyridoxal phosphate binding|carbohydrate binding|",10,1.6,1.96,10,0.1,0.303,0,0,0,0.832,0,0,-0.5,3
ENSMUSG00000024926,KAT5,K(lysine) acetyltransferase 5,chromatin|Swr1 complex|nucleus|transcription factor complex|cytoplasm|cytosol|Piccolo NuA4 histone acetyltransferase complex|NuA4 histone acetyltransferase complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|response to ionizing radiation|chromatin modification|histone acetylation|negative regulation of interleukin-2 production|regulation of growth|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cellular response to estradiol stimulus|","transcription coactivator activity|transcription coactivator activity|histone acetyltransferase activity|histone acetyltransferase activity|protein binding|transcription factor binding|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|protein complex binding|metal ion binding|repressing transcription factor binding|",9,-0.2,0.824,9,0.2,0.648,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000025317,CAR5A,"carbonic anhydrase 5a, mitochondrial",mitochondrion|mitochondrion|,gluconeogenesis|one-carbon metabolic process|,carbonate dehydratase activity|carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,0,0,10,-0.1,0.0428,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000074486,BGLAP2,bone gamma-carboxyglutamate protein 2,extracellular region|extracellular space|extracellular space|cytoplasm|rough endoplasmic reticulum|Golgi apparatus|dendrite|membrane-bounded vesicle|cell projection|perikaryon|,regulation of bone mineralization|pancreas development|biomineral tissue development|positive regulation of insulin secretion|cellular response to insulin stimulus|cellular response to insulin stimulus|glucose homeostasis|cellular lipid catabolic process|type B pancreatic cell proliferation|,calcium ion binding|structural constituent of bone|hydroxyapatite binding|metal ion binding|,10,0,0,10,-0.2,0.636,0,0,0,0.832,0,0,-1.6,1.3
ENSMUSG00000045613,CHRM2,"cholinergic receptor, muscarinic 2, cardiac",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled acetylcholine receptor signaling pathway|synaptic transmission|regulation of heart contraction|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled acetylcholine receptor activity|,10,-0.1,0.00919,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000030203,DUSP16,dual specificity phosphatase 16,nucleus|nucleus|cytoplasm|cytosol|,inactivation of MAPK activity|protein dephosphorylation|phosphorylation|dephosphorylation|negative regulation of MAPK cascade|,protein binding|protein tyrosine/serine/threonine phosphatase activity|kinase activity|transferase activity|hydrolase activity|phosphatase activity|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.4,1.7
ENSMUSG00000021646,MCCC2,methylcrotonoyl-Coenzyme A carboxylase 2 (beta),mitochondrion|mitochondrion|,coenzyme A metabolic process|,nucleotide binding|methylcrotonoyl-CoA carboxylase activity|methylcrotonoyl-CoA carboxylase activity|ATP binding|ligase activity|,10,0.4,1.06,10,-0.1,0.102,0,0,0,0.832,0,0,-0.9,2
ENSMUSG00000029120,PPP2R2C,"protein phosphatase 2, regulatory subunit B, gamma",protein phosphatase type 2A complex|,signal transduction|,protein phosphatase type 2A regulator activity|,10,0,0,10,0.2,0.165,0,0,0,0.832,0,0,-1.2,1.7
ENSMUSG00000037370,ENPP1,ectonucleotide pyrophosphatase/phosphodiesterase 1,extracellular region|extracellular space|extracellular space|lysosomal membrane|plasma membrane|integral component of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|,generation of precursor metabolites and energy|ATP catabolic process|phosphate-containing compound metabolic process|immune response|metabolic process|nucleoside triphosphate catabolic process|negative regulation of ossification|negative regulation of cell growth|inorganic diphosphate transport|cellular phosphate ion homeostasis|sequestering of triglyceride|biomineral tissue development|negative regulation of protein autophosphorylation|cellular response to insulin stimulus|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|negative regulation of glycogen biosynthetic process|negative regulation of glucose import|negative regulation of insulin receptor signaling pathway|bone remodeling|3'-phosphoadenosine 5'-phosphosulfate metabolic process|nucleic acid phosphodiester bond hydrolysis|,nucleic acid binding|catalytic activity|phosphodiesterase I activity|nucleotide diphosphatase activity|nucleotide diphosphatase activity|scavenger receptor activity|insulin receptor binding|calcium ion binding|ATP binding|zinc ion binding|hydrolase activity|polysaccharide binding|NADH pyrophosphatase activity|protein homodimerization activity|metal ion binding|nucleoside-triphosphate diphosphatase activity|,9,-0.6,0.868,9,0,0,0,0,0,0.832,0,0,-2,0.9
ENSMUSG00000056035,CYP3A11,"cytochrome P450, family 3, subfamily a, polypeptide 11",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|demethylation|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|demethylase activity|metal ion binding|testosterone 6-beta-hydroxylase activity|aromatase activity|",9,0.1,0.146,9,-0.1,0.293,0,0,0,0.832,0,0,-1.8,1.3
ENSMUSG00000048217,NAGS,N-acetylglutamate synthase,mitochondrion|mitochondrion|,urea cycle|glutamate metabolic process|,"acetyl-CoA:L-glutamate N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.6,0.74,10,1.3,1.39,0,0,0,0.832,0,0,-1.4,2
ENSMUSG00000027499,PKIA,"protein kinase inhibitor, alpha",nucleus|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of protein kinase activity|regulation of G2/M transition of mitotic cell cycle|negative regulation of protein import into nucleus|negative regulation of catalytic activity|negative regulation of protein serine/threonine kinase activity|negative regulation of cAMP-dependent protein kinase activity|,protein kinase inhibitor activity|cAMP-dependent protein kinase inhibitor activity|cAMP-dependent protein kinase inhibitor activity|protein kinase A catalytic subunit binding|,10,0.1,0.0738,10,-0.1,0.247,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000022809,NR1I2,"nuclear receptor subfamily 1, group I, member 2",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|xenobiotic metabolic process|positive regulation of gene expression|intracellular receptor signaling pathway|exogenous drug catabolic process|xenobiotic transport|steroid hormone mediated signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|drug export|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|drug binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-1,0.16,10,0.2,0.286,0,0,0,0.832,0,0,-2,1
ENSMUSG00000028003,LRAT,lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase),cytoplasm|endosome|multivesicular body|endoplasmic reticulum|rough endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,"1,2-diacyl-sn-glycero-3-phosphocholine metabolic process|vitamin A metabolic process|vitamin A metabolic process|visual perception|embryo development|positive regulation of lipid transport|retinol metabolic process|retinol metabolic process|retinol metabolic process|response to stimulus|","retinoic acid binding|O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|retinol binding|phosphatidylcholine-retinol O-acyltransferase activity|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000003352,CACNB3,"calcium channel, voltage-dependent, beta 3 subunit",voltage-gated calcium channel complex|voltage-gated calcium channel complex|membrane|apical plasma membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|T cell receptor signaling pathway|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|high voltage-gated calcium channel activity|protein kinase binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000029545,ACADS,"acyl-Coenzyme A dehydrogenase, short chain",nucleus|mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial membrane|,lipid metabolic process|fatty acid metabolic process|metabolic process|fatty acid beta-oxidation using acyl-CoA dehydrogenase|butyrate catabolic process|protein homotetramerization|oxidation-reduction process|,"fatty-acyl-CoA binding|acyl-CoA dehydrogenase activity|butyryl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|flavin adenine dinucleotide binding|",10,0.1,0.0621,10,0,0,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000036896,C1QC,"complement component 1, q subcomponent, C chain",extracellular region|collagen trimer|extracellular space|membrane|extracellular vesicular exosome|blood microparticle|,"immune system process|immune response|complement activation, classical pathway|negative regulation of granulocyte differentiation|innate immune response|negative regulation of macrophage differentiation|",tumor necrosis factor receptor binding|,10,-0.1,0.093,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000029064,GNB1,"guanine nucleotide binding protein (G protein), beta 1",photoreceptor outer segment|photoreceptor inner segment|lysosomal membrane|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|dendrite|photoreceptor outer segment membrane|cell body|extracellular vesicular exosome|,"GTP catabolic process|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|phototransduction, visible light|cell proliferation|cardiac muscle cell apoptotic process|sensory perception of taste|retina development in camera-type eye|cellular response to hypoxia|",G-protein coupled receptor binding|GTPase activity|signal transducer activity|spectrin binding|type 1 angiotensin receptor binding|protein complex binding|GTPase binding|,10,0,0,10,0.1,0.0508,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000024896,MINPP1,multiple inositol polyphosphate histidine phosphatase 1,endoplasmic reticulum|plasma membrane|membrane|extracellular vesicular exosome|,dephosphorylation|,"acid phosphatase activity|inositol-hexakisphosphate phosphatase activity|hydrolase activity|phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|bisphosphoglycerate 3-phosphatase activity|inositol hexakisphosphate 2-phosphatase activity|",10,0,0,10,0.1,0.159,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000061718,PPP1R1B,"protein phosphatase 1, regulatory (inhibitor) subunit 1B",intracellular|nucleus|cytoplasm|cytoplasm|neuronal cell body|,"response to amphetamine|transcription, DNA-templated|signal transduction|negative regulation of female receptivity|negative regulation of female receptivity|visual learning|intracellular signal transduction|negative regulation of catalytic activity|",protein phosphatase inhibitor activity|protein serine/threonine phosphatase inhibitor activity|D1 dopamine receptor binding|D2 dopamine receptor binding|D3 dopamine receptor binding|D4 dopamine receptor binding|D5 dopamine receptor binding|,10,-1,0.035,10,-0.1,0.145,0,0,0,0.832,0,0,-2,0.7
ENSMUSG00000049115,AGTR1A,"angiotensin II receptor, type 1a",cell|cytoplasm|endosome|Golgi apparatus|plasma membrane|plasma membrane|endomembrane system|vesicle membrane|membrane|integral component of membrane|basolateral plasma membrane|dendrite|cytoplasmic vesicle|organelle outer membrane|vesicle lumen|recycling endosome|,blood vessel development|kidney development|kidney development|kidney development|positive regulation of receptor recycling|regulation of systemic arterial blood pressure by circulatory renin-angiotensin|renin secretion into blood stream|renin-angiotensin regulation of aldosterone production|renin-angiotensin regulation of aldosterone production|regulation of renal output by angiotensin|brain renin-angiotensin system|regulation of pH|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|Rho protein signal transduction|heart development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cholesterol esterification|regulation of vasoconstriction|calcium-mediated signaling|positive regulation of cellular protein metabolic process|positive regulation of phospholipase A2 activity|positive regulation of superoxide anion generation|regulation of smooth muscle cell apoptotic process|negative regulation of smooth muscle cell apoptotic process|angiotensin-activated signaling pathway|vasoconstriction|dopamine biosynthetic process|drinking behavior|drinking behavior|drinking behavior|activation of Janus kinase activity|response to estrogen|positive regulation of blood pressure|positive regulation of blood pressure|positive regulation of blood pressure|positive regulation of blood pressure|positive regulation of cytokine secretion|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|cell chemotaxis|cellular response to dexamethasone stimulus|phospholipase C-activating angiotensin-activated signaling pathway|phospholipase C-activating angiotensin-activated signaling pathway|positive regulation of branching involved in ureteric bud morphogenesis|,angiotensin type I receptor activity|angiotensin type I receptor activity|G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|angiotensin type II receptor activity|protein binding|peptide hormone binding|protein kinase binding|bradykinin receptor binding|D1 dopamine receptor binding|protein self-association|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000053825,PPFIA2,"protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2",cytoplasm|synapse|extracellular vesicular exosome|,biological_process|,protein binding|protein complex binding|,10,0.2,0.57,10,-0.1,0.0838,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000037060,PRKCDBP,"protein kinase C, delta binding protein",caveola|protein complex|,cortical actin cytoskeleton organization|negative regulation of protein kinase B signaling|positive regulation of ERK1 and ERK2 cascade|negative regulation of fermentation|,protein kinase C binding|protein kinase C binding|protein binding|,10,-0.1,0.198,10,0.2,0.369,0,0,0,0.832,0,0,-1.3,1.6
ENSMUSG00000027890,GSTM4,"glutathione S-transferase, mu 4",cytoplasm|cytosol|,glutathione metabolic process|nitrobenzene metabolic process|xenobiotic catabolic process|xenobiotic catabolic process|,glutathione transferase activity|glutathione transferase activity|transferase activity|enzyme binding|protein homodimerization activity|glutathione binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000070304,SCN2B,"sodium channel, voltage-gated, type II, beta",voltage-gated sodium channel complex|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|response to pyrethroid|cardiac muscle contraction|regulation of atrial cardiac muscle cell membrane depolarization|cardiac muscle cell action potential involved in contraction|membrane depolarization during cardiac muscle cell action potential|regulation of heart rate by cardiac conduction|regulation of sodium ion transmembrane transporter activity|,voltage-gated ion channel activity|voltage-gated sodium channel activity|sodium channel activity|sodium channel regulator activity|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.5,1.7
ENSMUSG00000061099,GAPDHS,"glyceraldehyde-3-phosphate dehydrogenase, spermatogenic",nucleus|cytoplasm|cilium|motile cilium|motile cilium|sperm fibrous sheath|sperm principal piece|,glucose metabolic process|glycolytic process|sperm motility|sperm motility|positive regulation of glycolytic process|oxidation-reduction process|,"glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity|glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|NADP binding|NAD binding|",10,1.1,2.26,10,-0.1,0.0609,0,0,0,0.832,0,0,-0.9,2
ENSMUSG00000001270,CKB,"creatine kinase, brain",cytoplasm|mitochondrion|extracellular vesicular exosome|,phosphorylation|cellular chloride ion homeostasis|,"nucleotide binding|catalytic activity|creatine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,9,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000045875,ADRA1A,"adrenergic receptor, alpha 1a",nucleus|plasma membrane|membrane|membrane|integral component of membrane|Z disc|T-tubule|nuclear membrane|,"negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure|norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure|positive regulation of heart rate by epinephrine-norepinephrine|positive regulation of the force of heart contraction by epinephrine-norepinephrine|positive regulation of systemic arterial blood pressure|regulation of muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|activation of phospholipase C activity|positive regulation of cytosolic calcium ion concentration|adult heart development|aging|response to hormone|positive regulation of heart rate|cell growth|regulation of vasoconstriction|positive regulation of synaptic transmission, GABAergic|negative regulation of Rho protein signal transduction|organ growth|response to drug|positive regulation of MAPK cascade|positive regulation of MAPK cascade|positive regulation of action potential|positive regulation of vasoconstriction|positive regulation of smooth muscle contraction|positive regulation of smooth muscle contraction|regulation of cardiac muscle contraction|micturition|calcium ion transport into cytosol|positive regulation of cardiac muscle contraction|positive regulation of ERK1 and ERK2 cascade|adrenergic receptor signaling pathway|adrenergic receptor signaling pathway|positive regulation of protein kinase C signaling|pilomotor reflex|",signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|alpha1-adrenergic receptor activity|alpha1-adrenergic receptor activity|alpha1-adrenergic receptor activity|protein heterodimerization activity|,10,0.1,0.278,10,0,0,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000053329,D10JHU81E,"DNA segment, Chr 10, Johns Hopkins University 81 expressed",mitochondrion|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0278,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000026272,AGXT,alanine-glyoxylate aminotransferase,mitochondrion|mitochondrion|mitochondrial matrix|peroxisome|peroxisome|peroxisomal matrix|,"protein targeting to peroxisome|metabolic process|glyoxylate catabolic process|glycine biosynthetic process, by transamination of glyoxylate|L-cysteine catabolic process|L-alanine catabolic process|pyruvate biosynthetic process|glyoxylate metabolic process|glyoxylate metabolic process|oxalic acid secretion|response to glucocorticoid|response to cAMP|",catalytic activity|serine-pyruvate transaminase activity|receptor binding|alanine-glyoxylate transaminase activity|alanine-glyoxylate transaminase activity|transaminase activity|amino acid binding|transferase activity|pyridoxal phosphate binding|protein homodimerization activity|,10,0.2,0.0706,10,0,0,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000057897,CAMK2B,"calcium/calmodulin-dependent protein kinase II, beta",cytoplasm|cytosol|cytoskeleton|calcium- and calmodulin-dependent protein kinase complex|membrane|sarcoplasmic reticulum|spindle midzone|,"G1/S transition of mitotic cell cycle|inhibitory G-protein coupled receptor phosphorylation|protein phosphorylation|calcium ion transport|nervous system development|positive regulation of neuron projection development|phosphorylation|peptidyl-serine phosphorylation|cell differentiation|regulation of synaptic transmission, cholinergic|response to cadmium ion|protein autophosphorylation|protein autophosphorylation|regulation of long-term neuronal synaptic plasticity|neuromuscular process controlling balance|long-term synaptic potentiation|activation of meiosis involved in egg activation|positive regulation of dendritic spine morphogenesis|positive regulation of synapse maturation|positive regulation of apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.00979,10,0,0,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000078365,MOS,Moloney sarcoma oncogene,cytosol|,protein phosphorylation|phosphorylation|regulation of meiosis|,nucleotide binding|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|,10,0.4,1.61,10,0,0,0,0,0,0.832,0,0,-2,1.1
ENSMUSG00000024558,MAPK4,mitogen-activated protein kinase 4,nucleus|cytoplasm|,protein phosphorylation|cell cycle|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein homodimerization activity|protein heterodimerization activity|",10,-0.1,0.0688,10,0,0,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000031934,PANX1,pannexin 1,endoplasmic reticulum|plasma membrane|plasma membrane|plasma membrane|gap junction|membrane|membrane|integral component of membrane|cell junction|bleb|protein complex|,response to ischemia|transport|ion transport|cation transport|calcium ion transport|cell-cell signaling|response to ATP|protein hexamerization|positive regulation of cytokine secretion|positive regulation of interleukin-1 alpha secretion|positive regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|transmembrane transport|calcium ion transmembrane transport|,protease binding|actin binding|receptor binding|gap junction channel activity|calcium channel activity|protein binding|channel activity|leak channel activity|ion channel binding|protein heterodimerization activity|actin filament binding|gap junction hemi-channel activity|scaffold protein binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000028194,DDAH1,dimethylarginine dimethylaminohydrolase 1,cytoplasm|mitochondrion|extracellular vesicular exosome|,citrulline metabolic process|regulation of systemic arterial blood pressure|arginine metabolic process|nitric oxide biosynthetic process|protein nitrosylation|positive regulation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthetic process|positive regulation of angiogenesis|,"zinc ion binding|dimethylargininase activity|dimethylargininase activity|dimethylargininase activity|amino acid binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines|metal ion binding|",10,0,0,10,-0.1,0.421,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000019528,GYG,glycogenin,membrane|extracellular vesicular exosome|,glycogen biosynthetic process|,"glucose binding|glycogenin glucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",9,0.4,1.63,9,0,0,0,0,0,0.832,0,0,-1.1,1.8
ENSMUSG00000021871,PNP,purine-nucleoside phosphorylase,extracellular region|intracellular|intracellular|nucleus|cytoplasm|cytosol|cytoskeleton|extracellular vesicular exosome|,positive regulation of T cell mediated cytotoxicity|nucleobase-containing compound metabolic process|inosine catabolic process|inosine catabolic process|deoxyinosine catabolic process|deoxyguanosine catabolic process|GTP biosynthetic process|intrinsic apoptotic signaling pathway in response to DNA damage|apoptotic mitochondrial changes|nucleoside metabolic process|response to gamma radiation|urate biosynthetic process|urate biosynthetic process|positive regulation of T cell proliferation|positive regulation of T cell proliferation|purine nucleoside metabolic process|purine nucleoside metabolic process|purine nucleoside metabolic process|positive regulation of B cell differentiation|positive regulation of DNA repair|dGTP metabolic process|guanosine catabolic process|positive regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell differentiation|negative regulation of T cell apoptotic process|,"nucleoside binding|purine nucleobase binding|catalytic activity|purine-nucleoside phosphorylase activity|purine-nucleoside phosphorylase activity|purine-nucleoside phosphorylase activity|drug binding|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring pentosyl groups|phosphate ion binding|",10,0.5,2.35,10,0,0,0,0,0,0.832,0,0,-0.7,2
ENSMUSG00000000901,MMP11,matrix metallopeptidase 11,extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular matrix|,proteolysis|multicellular organismal development|extracellular matrix organization|collagen fibril organization|collagen catabolic process|negative regulation of fat cell differentiation|basement membrane organization|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.276,10,0,0,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000032988,SLC16A8,"solute carrier family 16 (monocarboxylic acid transporters), member 8",plasma membrane|basal plasma membrane|membrane|integral component of membrane|,transport|organic anion transport|transmembrane transport|,symporter activity|secondary active monocarboxylate transmembrane transporter activity|,10,0,0,10,-0.1,0.115,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000011179,ODC1,"ornithine decarboxylase, structural 1",cytoplasm|cytosol|perinuclear region of cytoplasm|,kidney development|polyamine metabolic process|polyamine biosynthetic process|positive regulation of cell proliferation|putrescine biosynthetic process|,catalytic activity|ornithine decarboxylase activity|ornithine decarboxylase activity|lyase activity|carboxy-lyase activity|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.7,1.5
ENSMUSG00000026064,PTP4A1,protein tyrosine phosphatase 4a1,nucleus|cytoplasm|endosome|endoplasmic reticulum|cytoskeleton|plasma membrane|cytoplasmic side of plasma membrane|membrane|extracellular vesicular exosome|,protein dephosphorylation|cell cycle|multicellular organismal development|dephosphorylation|positive regulation of cell migration|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|prenylated protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.2,1.7
ENSMUSG00000032786,ALAS1,aminolevulinic acid synthase 1,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial matrix|,porphyrin-containing compound metabolic process|heme biosynthetic process|metabolic process|biosynthetic process|tetrapyrrole biosynthetic process|,"catalytic activity|5-aminolevulinate synthase activity|transferase activity|transferase activity, transferring acyl groups|pyridoxal phosphate binding|",10,-0.2,0.387,10,0,0,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000023047,AMHR2,anti-Mullerian hormone type 2 receptor,integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,protein phosphorylation|signal transduction|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|G-protein coupled receptor signaling pathway|sex differentiation|phosphorylation|negative regulation of anti-Mullerian hormone signaling pathway|anti-Mullerian hormone signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|receptor activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta receptor activity, type II|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|hormone binding|metal ion binding|anti-Mullerian hormone receptor activity|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000004654,GHRHR,growth hormone releasing hormone receptor,cell|nuclear inner membrane|nuclear outer membrane|cytoplasm|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|integral component of membrane|nuclear matrix|secretory granule|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|lactation|positive regulation of cell proliferation|positive regulation of cell proliferation|determination of adult lifespan|cAMP-mediated signaling|adenohypophysis development|water homeostasis|growth hormone secretion|positive regulation of cAMP metabolic process|positive regulation of cAMP biosynthetic process|mammary gland development|response to insulin|cellular response to insulin stimulus|regulation of intracellular steroid hormone receptor signaling pathway|positive regulation of multicellular organism growth|positive regulation of multicellular organism growth|positive regulation of multicellular organism growth|hormone metabolic process|regulation of insulin-like growth factor receptor signaling pathway|response to estrogen|positive regulation of hormone secretion|cell maturation|regulation of protein metabolic process|response to glucocorticoid|positive regulation of growth hormone secretion|somatotropin secreting cell development|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|growth hormone-releasing hormone receptor activity|growth hormone-releasing hormone receptor activity|growth hormone-releasing hormone receptor activity|peptide hormone binding|peptide hormone binding|growth factor binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.2,1.8
ENSMUSG00000024617,CAMK2A,calcium/calmodulin-dependent protein kinase II alpha,nucleus|cytoplasm|mitochondrion|plasma membrane|calcium- and calmodulin-dependent protein kinase complex|membrane|cell junction|dendrite|dendrite cytoplasm|synapse|,G1/S transition of mitotic cell cycle|response to ischemia|protein phosphorylation|protein phosphorylation|calcium ion transport|positive regulation of cardiac muscle cell apoptotic process|phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|ionotropic glutamate receptor signaling pathway|protein autophosphorylation|protein autophosphorylation|regulation of neurotransmitter secretion|regulation of neuronal synaptic plasticity|positive regulation of NF-kappaB transcription factor activity|positive regulation of calcium ion transport|regulation of mitochondrial membrane permeability involved in apoptotic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|GTPase activating protein binding|glutamate receptor binding|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000038764,PTPN3,"protein tyrosine phosphatase, non-receptor type 3",cytoplasm|cytoskeleton|plasma membrane|cytoplasmic side of plasma membrane|membrane|,protein dephosphorylation|phosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|negative regulation of mitotic cell cycle|negative regulation of membrane protein ectodomain proteolysis|,phosphotyrosine binding|protein tyrosine kinase activity|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|cytoskeletal protein binding|kinase activity|transferase activity|hydrolase activity|phosphatase activity|ATPase binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.3,1.8
ENSMUSG00000068417,PNP2,purine-nucleoside phosphorylase 2,extracellular region|intracellular|nucleus|cytoplasm|extracellular vesicular exosome|,biological_process|,"nucleoside binding|purine nucleobase binding|purine-nucleoside phosphorylase activity|drug binding|transferase activity|transferase activity, transferring glycosyl groups|phosphate ion binding|",10,-0.3,0.295,10,0,0,0,0,0,0.832,0,0,-1.9,0.9
ENSMUSG00000059742,KCNH7,"potassium voltage-gated channel, subfamily H (eag-related), member 7",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|signal transduction|regulation of ion transmembrane transport|regulation of membrane potential|protein heterooligomerization|transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,signal transducer activity|ion channel activity|inward rectifier potassium channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|potassium channel activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000031482,SLC25A15,"solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|,None,10,0.1,0.0776,10,0,0,0,0,0,0.832,0,0,-1.4,1.7
ENSMUSG00000027931,NPR1,natriuretic peptide receptor 1,intracellular|plasma membrane|membrane|integral component of membrane|receptor complex|,cGMP biosynthetic process|cGMP biosynthetic process|protein phosphorylation|cell surface receptor signaling pathway|receptor guanylyl cyclase signaling pathway|cyclic nucleotide biosynthetic process|positive regulation of cGMP biosynthetic process|intracellular signal transduction|dopamine metabolic process|negative regulation of smooth muscle cell proliferation|regulation of blood vessel size|,"nucleotide binding|guanylate cyclase activity|guanylate cyclase activity|guanylate cyclase activity|protein kinase activity|ATP binding|GTP binding|transferase activity, transferring phosphorus-containing groups|lyase activity|phosphorus-oxygen lyase activity|natriuretic peptide receptor activity|peptide hormone binding|protein kinase binding|hormone binding|",9,0,0,9,0,0,0,0,0,0.832,0,0,-1.5,1.7
ENSMUSG00000034449,DHRS11,dehydrogenase/reductase (SDR family) member 11,cellular_component|extracellular region|,biological_process|metabolic process|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.3,0.345,10,-0.3,0.226,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000041313,SLC7A1,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 1",plasma membrane|membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|arginine transport|arginine transport|regulation of TOR signaling|,amino acid transmembrane transporter activity|arginine transmembrane transporter activity|arginine transmembrane transporter activity|,10,0.3,0.353,10,-0.1,0.0961,0,0,0,0.832,0,0,-1.1,1.9
ENSMUSG00000001249,HPN,hepsin,endoplasmic reticulum membrane|plasma membrane|plasma membrane|integral component of plasma membrane|cell-cell junction|cell surface|membrane|integral component of membrane|nuclear membrane|neuronal cell body|extracellular vesicular exosome|,proteolysis|sensory perception of sound|regulation of cell shape|positive regulation of gene expression|negative regulation of alkaline phosphatase activity|negative regulation of epithelial to mesenchymal transition|positive regulation of plasminogen activation|positive regulation of cell growth|basement membrane disassembly|cholesterol homeostasis|negative regulation of apoptotic process|positive regulation by host of viral transcription|negative regulation of epithelial cell proliferation|detection of mechanical stimulus involved in sensory perception of sound|potassium ion transmembrane transport|cochlea morphogenesis|response to thyroid hormone|pilomotor reflex|positive regulation of hepatocyte proliferation|positive regulation of thyroid hormone generation|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|calcium-activated potassium channel activity|hydrolase activity|serine-type exopeptidase activity|,10,0.1,0.148,10,-0.1,0.0437,0,0,0,0.832,0,0,-1.3,1.7
ENSMUSG00000027562,CAR2,carbonic anhydrase 2,extracellular space|cytoplasm|cytosol|plasma membrane|microvillus|membrane|basolateral plasma membrane|axon|myelin sheath|apical part of cell|extracellular vesicular exosome|,"morphogenesis of an epithelium|one-carbon metabolic process|regulation of pH|carbon dioxide transport|carbon dioxide transport|positive regulation of synaptic transmission, GABAergic|positive regulation of cellular pH reduction|positive regulation of cellular pH reduction|angiotensin-activated signaling pathway|regulation of anion transport|positive regulation of osteoclast differentiation|positive regulation of bone resorption|secretion|regulation of intracellular pH|positive regulation of dipeptide transmembrane transport|regulation of chloride transport|",carbonate dehydratase activity|carbonate dehydratase activity|carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,-0.2,0.533,10,0,0,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000074218,COX7A1,cytochrome c oxidase subunit VIIa 1,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain|membrane|integral component of membrane|,oxidation-reduction process|hydrogen ion transmembrane transport|,cytochrome-c oxidase activity|electron carrier activity|,10,0.1,0.118,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000007039,DDAH2,dimethylarginine dimethylaminohydrolase 2,cytoplasm|mitochondrion|extracellular vesicular exosome|,citrulline metabolic process|arginine metabolic process|arginine catabolic process|,"dimethylargininase activity|amino acid binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines|",10,0.3,1.08,10,0,0,0,0,0,0.832,0,0,-1,1.9
ENSMUSG00000020178,ADORA2A,adenosine A2a receptor,intermediate filament|plasma membrane|plasma membrane|integral component of plasma membrane|endomembrane system|postsynaptic density|membrane|membrane|integral component of membrane|axon|dendrite|axolemma|asymmetric synapse|presynaptic membrane|neuronal cell body|postsynaptic membrane|presynaptic active zone|,"synaptic transmission, dopaminergic|adenosine receptor signaling pathway|adenosine receptor signaling pathway|adenosine receptor signaling pathway|adenosine receptor signaling pathway|response to amphetamine|regulation of transcription, DNA-templated|negative regulation of protein kinase activity|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|synaptic transmission, cholinergic|locomotory behavior|locomotory behavior|negative regulation of cell proliferation|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of glutamate secretion|positive regulation of acetylcholine secretion, neurotransmission|regulation of norepinephrine secretion|positive regulation of cAMP biosynthetic process|response to caffeine|positive regulation of synaptic transmission, GABAergic|positive regulation of synaptic transmission, GABAergic|synaptic transmission, glutamatergic|positive regulation of urine volume|positive regulation of renal sodium excretion|negative regulation of locomotion|vasodilation|eating behavior|eating behavior|negative regulation of vascular permeability|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|response to alkaloid|negative regulation of neuron apoptotic process|positive regulation of circadian sleep/wake cycle, sleep|negative regulation of alpha-beta T cell activation|astrocyte activation|regulation of synaptic plasticity|neuron projection morphogenesis|positive regulation of protein secretion|negative regulation of inflammatory response|regulation of mitochondrial membrane potential|membrane depolarization|regulation of calcium ion transport|positive regulation of synaptic transmission, glutamatergic|regulation of excitatory postsynaptic membrane potential|regulation of inhibitory postsynaptic membrane potential|prepulse inhibition|positive regulation of apoptotic signaling pathway|",G-protein coupled adenosine receptor activity|G-protein coupled adenosine receptor activity|G-protein coupled adenosine receptor activity|signal transducer activity|G-protein coupled receptor activity|enzyme binding|type 5 metabotropic glutamate receptor binding|identical protein binding|protein heterodimerization activity|alpha-actinin binding|,10,0,0,10,-0.1,0.0978,0,0,0,0.832,0,0,-2,0.8
ENSMUSG00000026544,DUSP23,dual specificity phosphatase 23,nucleus|cytoplasm|extracellular vesicular exosome|,protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,0,0,9,0,0,0,0,0,0.832,0,0,-1.4,1.8
ENSMUSG00000029522,PLA2G1B,"phospholipase A2, group IB, pancreas",extracellular region|extracellular region|extracellular space|cell surface|secretory granule|,innate immune response in mucosa|lipid metabolic process|fatty acid biosynthetic process|phospholipid metabolic process|phospholipid catabolic process|lipid catabolic process|antibacterial humoral response|multicellular organismal lipid catabolic process|positive regulation of DNA replication|phosphatidylcholine metabolic process|defense response to Gram-positive bacterium|,phospholipase A2 activity|phospholipase A2 activity|receptor binding|receptor binding|calcium ion binding|hydrolase activity|metal ion binding|calcium-dependent phospholipase A2 activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.1,2
ENSMUSG00000041248,KCNJ1,"potassium inwardly-rectifying channel, subfamily J, member 1",plasma membrane|membrane|integral component of membrane|,kidney development|tissue homeostasis|transport|ion transport|potassium ion transport|post-embryonic development|regulation of ion transmembrane transport|negative regulation of apoptotic process|renal sodium ion absorption|cellular response to magnesium ion|potassium ion transmembrane transport|cardiovascular system development|regulation of G-protein activated inward rectifier potassium channel activity|,"nucleotide binding|inward rectifier potassium channel activity|voltage-gated ion channel activity|ATP binding|phosphatidylinositol-4,5-bisphosphate binding|ATP-activated inward rectifier potassium channel activity|potassium ion binding|peptide binding|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000001729,AKT1,thymoma viral proto-oncogene 1,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|spindle|cytosol|plasma membrane|plasma membrane|cell-cell junction|microtubule cytoskeleton|membrane|ciliary basal body|,"protein import into nucleus, translocation|osteoblast differentiation|maternal placenta development|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|carbohydrate metabolic process|glycogen metabolic process|glycogen biosynthetic process|regulation of glycogen biosynthetic process|glucose metabolic process|translation|regulation of translation|protein phosphorylation|protein phosphorylation|negative regulation of protein kinase activity|transport|apoptotic process|activation-induced cell death of T cells|inflammatory response|cytoskeleton organization|signal transduction|multicellular organismal development|germ cell development|nervous system development|aging|insulin receptor signaling pathway|insulin receptor signaling pathway|apoptotic mitochondrial changes|carbohydrate transport|response to hormone|negative regulation of autophagy|negative regulation of plasma membrane long-chain fatty acid transport|positive regulation of sodium ion transport|positive regulation of sodium ion transport|positive regulation of sodium ion transport|positive regulation of glucose metabolic process|negative regulation of endopeptidase activity|regulation of neuron projection development|glucose transport|phosphorylation|protein ubiquitination|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|cell projection organization|protein catabolic process|positive regulation of cell growth|regulation of cell migration|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|negative regulation of fatty acid beta-oxidation|response to food|positive regulation of cellular protein metabolic process|peripheral nervous system myelin maintenance|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular response to insulin stimulus|cellular response to insulin stimulus|cellular response to insulin stimulus|regulation of protein localization|regulation of protein localization|positive regulation of peptidyl-serine phosphorylation|response to fluid shear stress|intracellular signal transduction|glucose homeostasis|anagen|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|protein kinase B signaling|positive regulation of blood vessel endothelial cell migration|positive regulation of nitric oxide biosynthetic process|positive regulation of fat cell differentiation|positive regulation of glycogen biosynthetic process|negative regulation of cell size|negative regulation of proteolysis|positive regulation of vasoconstriction|positive regulation of transcription from RNA polymerase II promoter|positive regulation of glucose import|negative regulation of JNK cascade|positive regulation of lipid biosynthetic process|insulin-like growth factor receptor signaling pathway|positive regulation of nitric-oxide synthase activity|positive regulation of sequence-specific DNA binding transcription factor activity|striated muscle cell differentiation|glycogen cell differentiation involved in embryonic placenta development|labyrinthine layer blood vessel development|response to UV-A|cellular response to mechanical stimulus|cellular response to growth factor stimulus|cellular response to epidermal growth factor stimulus|cellular response to organic cyclic compound|cellular response to hypoxia|positive regulation of establishment of protein localization to plasma membrane|negative regulation of release of cytochrome c from mitochondria|cellular response to granulocyte macrophage colony-stimulating factor stimulus|execution phase of apoptosis|cellular response to peptide|","nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein kinase C binding|protein binding|ATP binding|phosphatidylinositol-3,4,5-trisphosphate binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|protein kinase binding|nitric-oxide synthase regulator activity|identical protein binding|phosphatidylinositol-3,4-bisphosphate binding|14-3-3 protein binding|",10,1,0.354,10,0,0,0,0,0,0.832,0,0,-1.1,2
ENSMUSG00000027762,SUCNR1,succinate receptor 1,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.1,0.0814,10,0.1,0.0166,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000070644,ETNK2,ethanolamine kinase 2,cellular_component|,in utero embryonic development|placenta development|lipid metabolic process|phosphatidylethanolamine biosynthetic process|phospholipid biosynthetic process|post-embryonic development|phosphorylation|multicellular organism growth|,"nucleotide binding|ethanolamine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.0265,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000019779,FRK,fyn-related kinase,nucleus|cytoplasm|plasma membrane|extracellular vesicular exosome|,protein phosphorylation|phosphorylation|peptidyl-tyrosine phosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.0888,10,0.1,0.54,0,0,0,0.832,0,0,-1.4,1.5
ENSMUSG00000030660,PIK3C2A,"phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide",nucleus|cytoplasm|Golgi apparatus|plasma membrane|plasma membrane|phosphatidylinositol 3-kinase complex|membrane|membrane|cytoplasmic vesicle|vesicle|extracellular vesicular exosome|,exocytosis|endocytosis|phosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|,"nucleotide binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|1-phosphatidylinositol-4-phosphate 3-kinase activity|phosphatidylinositol binding|",9,0.2,0.0681,9,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000061436,HIPK2,homeodomain interacting protein kinase 2,intracellular|nucleus|nucleus|cytoplasm|nuclear body|PML body|PML body|,"negative regulation of transcription from RNA polymerase II promoter|positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|cellular response to DNA damage stimulus|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|transforming growth factor beta receptor signaling pathway|smoothened signaling pathway|adult walking behavior|positive regulation of cell proliferation|adult locomotory behavior|anterior/posterior pattern specification|retina layer formation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|neuron differentiation|positive regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|positive regulation of protein binding|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of DNA binding|negative regulation of neuron apoptotic process|positive regulation of angiogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|embryonic camera-type eye morphogenesis|voluntary musculoskeletal movement|positive regulation of sequence-specific DNA binding transcription factor activity|embryonic retina morphogenesis in camera-type eye|lens induction in camera-type eye|SMAD protein signal transduction|iris morphogenesis|","nucleotide binding|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription coactivator activity|transcription corepressor activity|transcription corepressor activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SMAD binding|virion binding|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000060477,IRAK2,interleukin-1 receptor-associated kinase 2,None,regulation of cytokine-mediated signaling pathway|protein phosphorylation|signal transduction|lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|interleukin-1-mediated signaling pathway|response to interleukin-1|,"nucleotide binding|protein kinase activity|protein binding|ATP binding|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|protein heterodimerization activity|",10,-0.1,0.0101,10,0,0,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000073406,H2-BL,"histocompatibility 2, blastocyst",cytoplasm|endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,protection from natural killer cell mediated cytotoxicity|,receptor binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,-0.1,0.137,10,0.1,0.0303,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000027792,BCHE,butyrylcholinesterase,extracellular region|extracellular space|extracellular space|nuclear envelope lumen|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|membrane|blood microparticle|,"synaptic transmission, cholinergic|response to nutrient|learning|negative regulation of cell proliferation|neuroblast differentiation|choline metabolic process|choline metabolic process|response to drug|response to alkaloid|negative regulation of synaptic transmission|response to glucocorticoid|response to folic acid|",acetylcholinesterase activity|acetylcholinesterase activity|cholinesterase activity|cholinesterase activity|hydrolase activity|choline binding|identical protein binding|carboxylic ester hydrolase activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.4,1.7
ENSMUSG00000070687,HTR1D,5-hydroxytryptamine (serotonin) receptor 1D,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|serotonin receptor signaling pathway|synaptic transmission|response to toxic substance|intestine smooth muscle contraction|regulation of locomotion|vasoconstriction|regulation of behavior|,signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|serotonin receptor activity|serotonin binding|,10,0,0,10,-0.3,0.967,0,0,0,0.832,0,0,-1.8,1.1
ENSMUSG00000024079,EIF2AK2,eukaryotic translation initiation factor 2-alpha kinase 2,nucleus|cytoplasm|membrane|perinuclear region of cytoplasm|,"activation of MAPKK activity|positive regulation of cytokine production|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|translation|translational initiation|protein phosphorylation|protein phosphorylation|protein phosphorylation|response to virus|response to toxic substance|phosphorylation|negative regulation of translation|endoplasmic reticulum unfolded protein response|response to lipopolysaccharide|positive regulation of chemokine production|positive regulation of stress-activated MAPK cascade|response to vitamin E|negative regulation of osteoblast proliferation|response to interferon-alpha|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of viral genome replication|negative regulation of viral genome replication|innate immune response|protein autophosphorylation|protein autophosphorylation|positive regulation of NF-kappaB transcription factor activity|defense response to virus|regulation of NLRP3 inflammasome complex assembly|positive regulation of NIK/NF-kappaB signaling|regulation of hematopoietic progenitor cell differentiation|regulation of hematopoietic stem cell proliferation|regulation of hematopoietic stem cell differentiation|","nucleotide binding|RNA binding|double-stranded RNA binding|double-stranded RNA binding|translation initiation factor activity|protein kinase activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|",9,0,0,9,0.2,0.32,0,0,0,0.832,0,0,-1.7,1.5
ENSMUSG00000020886,DLG4,"discs, large homolog 4 (Drosophila)",cytoplasm|endoplasmic reticulum|plasma membrane|plasma membrane|synaptic vesicle|ionotropic glutamate receptor complex|postsynaptic density|postsynaptic density|membrane|cell junction|dendrite|cortical cytoskeleton|extrinsic component of cytoplasmic side of plasma membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|dendrite cytoplasm|juxtaparanode region of axon|juxtaparanode region of axon|cerebellar mossy fiber|neuron projection terminus|neuron spine|synapse|synapse|postsynaptic membrane|postsynaptic membrane|postsynaptic membrane|excitatory synapse|excitatory synapse|neuronal postsynaptic density|neuronal postsynaptic density|,negative regulation of receptor internalization|protein complex assembly|positive regulation of cytosolic calcium ion concentration|locomotory behavior|synaptic vesicle maturation|synaptic vesicle maturation|social behavior|protein localization to synapse|protein localization to synapse|locomotory exploration behavior|response to cocaine|establishment of protein localization|regulation of neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|positive regulation of synaptic transmission|neuromuscular process controlling balance|dendritic spine morphogenesis|dendritic spine morphogenesis|vocalization behavior|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|receptor localization to synapse|regulation of N-methyl-D-aspartate selective glutamate receptor activity|positive regulation of excitatory postsynaptic membrane potential|regulation of grooming behavior|,receptor binding|structural molecule activity|protein binding|protein C-terminus binding|protein phosphatase binding|PDZ domain binding|beta-1 adrenergic receptor binding|D1 dopamine receptor binding|P2Y1 nucleotide receptor binding|protein complex binding|acetylcholine receptor binding|glutamate receptor binding|ionotropic glutamate receptor binding|ionotropic glutamate receptor binding|neurexin family protein binding|scaffold protein binding|,10,0,0,10,0.7,1.7,0,0,0,0.832,0,0,-0.7,2
ENSMUSG00000040272,ACCS,1-aminocyclopropane-1-carboxylate synthase (non-functional),cellular_component|,biological_process|biosynthetic process|,catalytic activity|pyridoxal phosphate binding|,10,0,0,10,-0.6,0.176,0,0,0,0.832,0,0,-2,0.8
ENSMUSG00000027368,DUSP2,dual specificity phosphatase 2,nucleus|,endoderm formation|protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|mitogen-activated protein kinase binding|,10,0.4,0.42,10,0,0,0,0,0,0.832,0,0,-0.9,2
ENSMUSG00000074344,ADORA3,adenosine A3 receptor,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,adenosine receptor signaling pathway|adenosine receptor signaling pathway|histamine secretion by mast cell|histamine secretion by mast cell|positive regulation of leukocyte migration|positive regulation of leukocyte migration|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of mast cell degranulation|positive regulation of mast cell degranulation|positive regulation of inflammatory response|positive regulation of inflammatory response|positive regulation of calcium-mediated signaling|positive regulation of calcium-mediated signaling|positive regulation of mucus secretion|positive regulation of mucus secretion|,G-protein coupled adenosine receptor activity|G-protein coupled adenosine receptor activity|signal transducer activity|G-protein coupled receptor activity|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.7,1.6
ENSMUSG00000021665,HEXB,hexosaminidase B,acrosomal vesicle|lysosome|lysosome|membrane|membrane|extracellular vesicular exosome|,skeletal system development|carbohydrate metabolic process|N-acetylglucosamine metabolic process|glycosphingolipid metabolic process|ganglioside catabolic process|cellular calcium ion homeostasis|cellular calcium ion homeostasis|lysosome organization|lysosome organization|single fertilization|penetration of zona pellucida|sensory perception of sound|locomotory behavior|locomotory behavior|male courtship behavior|metabolic process|regulation of cell shape|phospholipid biosynthetic process|oligosaccharide catabolic process|lipid storage|lipid storage|sexual reproduction|glycosaminoglycan metabolic process|regulation of cellular metabolic process|myelination|astrocyte cell migration|cellular protein metabolic process|positive regulation of transcription from RNA polymerase II promoter|oogenesis|neuromuscular process controlling balance|neuromuscular process controlling balance|neuromuscular process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-N-acetylhexosaminidase activity|beta-N-acetylhexosaminidase activity|beta-N-acetylhexosaminidase activity|hexosaminidase activity|beta-N-acetylglucosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|protein homodimerization activity|protein homodimerization activity|protein heterodimerization activity|",10,0,0,10,0.1,0.276,0,0,0,0.832,0,0,-1.1,1.8
ENSMUSG00000032269,HTR3A,5-hydroxytryptamine (serotonin) receptor 3A,cytoplasm|plasma membrane|membrane|integral component of membrane|cell junction|axon|neuronal cell body|synapse|postsynaptic membrane|,transport|ion transport|cation transport|serotonin receptor signaling pathway|regulation of ion transmembrane transport|potassium ion transmembrane transport|,serotonin receptor activity|extracellular ligand-gated ion channel activity|serotonin-activated cation-selective channel activity|voltage-gated potassium channel activity|ligand-gated ion channel activity|serotonin binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000030602,PAK4,p21 protein (Cdc42/Rac)-activated kinase 4,cytoplasm|,protein phosphorylation|apoptotic process|cell cycle|phosphorylation|signal transduction by phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.67,10,0,0,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000027257,PACSIN3,protein kinase C and casein kinase substrate in neurons 3,cytoplasm|plasma membrane|membrane|extracellular vesicular exosome|,endocytosis|phosphorylation|negative regulation of endocytosis|negative regulation of endocytosis|positive regulation of membrane protein ectodomain proteolysis|negative regulation of calcium ion transport|membrane tubulation|membrane tubulation|,protein binding|cytoskeletal protein binding|lipid binding|lipid binding|kinase activity|transferase activity|calcium channel inhibitor activity|,10,0,0,10,-0.1,0.0526,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000026866,KYNU,kynureninase (L-kynurenine hydrolase),cytoplasm|mitochondrion|mitochondrion|cytosol|,tryptophan catabolic process|metabolic process|NAD biosynthetic process|pyridine nucleotide biosynthetic process|tryptophan catabolic process to kynurenine|tryptophan catabolic process to acetyl-CoA|quinolinate biosynthetic process|response to interferon-gamma|response to vitamin B6|anthranilate metabolic process|,catalytic activity|hydrolase activity|pyridoxal phosphate binding|kynureninase activity|protein homodimerization activity|,10,0,0,10,-0.1,0.226,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000041997,TLK1,tousled-like kinase 1,nucleus|,regulation of chromatin assembly or disassembly|protein phosphorylation|intracellular protein transport|cellular response to DNA damage stimulus|cell cycle|phosphorylation|chromatin modification|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.267,10,0.1,0.0775,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000022040,EPHX2,"epoxide hydrolase 2, cytoplasmic",cytoplasm|peroxisome|cytosol|extracellular vesicular exosome|,prostaglandin production involved in inflammatory response|lipid metabolic process|inflammatory response|metabolic process|response to toxic substance|positive regulation of gene expression|positive regulation of gene expression|dephosphorylation|sensory perception of pain|aromatic compound catabolic process|cholesterol homeostasis|cholesterol homeostasis|linoleic acid metabolic process|positive regulation of blood pressure|stilbene catabolic process|phospholipid dephosphorylation|regulation of cholesterol metabolic process|regulation of cholesterol metabolic process|,magnesium ion binding|catalytic activity|epoxide hydrolase activity|receptor binding|toxic substance binding|hydrolase activity|phosphatase activity|10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity|lipid phosphatase activity|protein homodimerization activity|metal ion binding|,10,-0.1,0.0633,10,0,0,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000006494,PDK1,"pyruvate dehydrogenase kinase, isoenzyme 1",intracellular|mitochondrion|plasma membrane|mitochondrial pyruvate dehydrogenase complex|pyruvate dehydrogenase complex|,carbohydrate metabolic process|glucose metabolic process|protein phosphorylation|cell surface receptor signaling pathway|cell proliferation|intrinsic apoptotic signaling pathway in response to oxidative stress|regulation of acetyl-CoA biosynthetic process from pyruvate|regulation of glucose metabolic process|phosphorylation|peptidyl-serine phosphorylation|intracellular signal transduction|hypoxia-inducible factor-1alpha signaling pathway|,nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|pyruvate dehydrogenase (acetyl-transferring) kinase activity|ATP binding|kinase activity|transferase activity|protein complex binding|protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,0.5,0.867,0,0,0,0.832,0,0,-0.8,2
ENSMUSG00000063796,SLC22A8,"solute carrier family 22 (organic anion transporter), member 8",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|extracellular vesicular exosome|,transport|ion transport|response to toxic substance|organic cation transport|quaternary ammonium group transport|ion transmembrane transport|glutathione transport|transmembrane transport|,protein kinase C binding|inorganic anion exchanger activity|organic anion transmembrane transporter activity|ion transmembrane transporter activity|quaternary ammonium group transmembrane transporter activity|transmembrane transporter activity|,10,-0.2,0.484,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000060499,RPL10L,ribosomal protein L10-like,intracellular|nucleus|ribosome|polysome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,10,0.3,0.816,10,-0.5,0.986,0,0,0,0.832,0,0,-1.6,1.6
ENSMUSG00000060036,RPL3,ribosomal protein L3,intracellular|nucleus|cytoplasm|ribosome|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|cellular response to interleukin-4|,structural constituent of ribosome|poly(A) RNA binding|,7,0,0,5,0.2,0.45,0,0,0,0.832,0,0,-1.3,2
ENSMUSG00000034761,MAP4K5,mitogen-activated protein kinase kinase kinase kinase 5,cytoplasm|plasma membrane|,MAPK cascade|activation of MAPKKK activity|protein phosphorylation|protein phosphorylation|phosphorylation|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000020155,KCNMB1,"potassium large conductance calcium-activated channel, subfamily M, beta member 1",voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|response to calcium ion|potassium ion transmembrane transport|,calcium-activated potassium channel activity|potassium channel regulator activity|,10,0.1,0.175,10,0,0,0,0,0,0.832,0,0,-1.2,1.8
ENSMUSG00000002043,TRAPPC6A,trafficking protein particle complex 6A,endoplasmic reticulum|Golgi apparatus|,transport|vesicle-mediated transport|,None,10,1.6,3.31,10,0,0,0,0,0,0.832,0,0,-0.4,3
ENSMUSG00000052305,HBB-BS,"hemoglobin, beta adult s chain",hemoglobin complex|haptoglobin-hemoglobin complex|extracellular vesicular exosome|blood microparticle|,None,peroxidase activity|oxygen binding|oxygen binding|hemoglobin binding|haptoglobin binding|hemoglobin alpha binding|hemoglobin beta binding|,10,0.2,0.666,10,-0.7,0.686,0,0,0,0.832,0,0,-2,1
ENSMUSG00000055172,C1RA,"complement component 1, r subcomponent A",extracellular region|blood microparticle|,"immune system process|proteolysis|complement activation|complement activation, classical pathway|innate immune response|",catalytic activity|serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,1.3,2.11,10,-0.1,0.0213,0,0,0,0.832,0,0,-0.8,2
ENSMUSG00000053716,DUSP7,dual specificity phosphatase 7,cytoplasm|cytosol|,inactivation of MAPK activity|protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|negative regulation of MAP kinase activity|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,9,0.1,0.207,10,-0.1,0.162,0,0,0,0.832,0,0,-1.9,1.1
ENSMUSG00000020993,TRAPPC6B,trafficking protein particle complex 6B,cellular_component|endoplasmic reticulum|Golgi apparatus|,transport|biological_process|vesicle-mediated transport|,molecular_function|,10,0.2,0.00304,10,0,0,0,0,0,0.832,0,0,-1.6,1.3
ENSMUSG00000009292,TRPM2,"transient receptor potential cation channel, subfamily M, member 2",plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|calcium ion transport|manganese ion transport|response to hydroperoxide|transmembrane transport|calcium ion transmembrane transport|manganese ion transmembrane transport|,ion channel activity|calcium channel activity|sodium channel activity|manganese ion transmembrane transporter activity|hydrolase activity|ADP-ribose diphosphatase activity|,10,0,0,10,0.1,0.0945,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000046008,PNLIP,pancreatic lipase,extracellular region|extracellular space|,lipid metabolic process|post-embryonic development|lipid catabolic process|intestinal cholesterol absorption|,catalytic activity|triglyceride lipase activity|lipase activity|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-2,0.9
ENSMUSG00000018623,MMP7,matrix metallopeptidase 7,extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular vesicular exosome|,antibacterial peptide secretion|proteolysis|collagen catabolic process|regulation of cell proliferation|response to drug|defense response to bacterium|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.1,0.141,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000025358,CDK2,cyclin-dependent kinase 2,"cyclin-dependent protein kinase holoenzyme complex|cyclin-dependent protein kinase holoenzyme complex|chromosome, telomeric region|condensed chromosome|X chromosome|Y chromosome|nucleus|nucleus|transcription factor complex|cytoplasm|endosome|cytosol|cytoskeleton|Cajal body|intracellular membrane-bounded organelle|","G1/S transition of mitotic cell cycle|DNA repair|protein phosphorylation|potassium ion transport|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|meiotic nuclear division|positive regulation of cell proliferation|phosphorylation|histone phosphorylation|positive regulation of DNA-dependent DNA replication initiation|cellular response to insulin stimulus|positive regulation of transcription, DNA-templated|cell division|response to cAMP|response to electrical stimulus|regulation of cell cycle|regulation of cell cycle|regulation of gene silencing|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|cyclin binding|protein complex binding|histone kinase activity|metal ion binding|",9,0,0,9,0,0,0,0,0,0.832,0,0,-1.2,1.9
ENSMUSG00000021123,RDH12,retinol dehydrogenase 12,intracellular|,visual perception|metabolic process|retinol metabolic process|response to stimulus|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|retinol dehydrogenase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,-0.1,0.0902,10,0.1,0.0336,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000068221,PDXP,"pyridoxal (pyridoxine, vitamin B6) phosphatase",cytoplasm|cytosol|cytoskeleton|plasma membrane|cell-cell junction|actin cytoskeleton|membrane|lamellipodium|midbody|cleavage furrow|ruffle membrane|cell projection|extracellular vesicular exosome|contractile ring|,protein dephosphorylation|regulation of mitosis|metabolic process|dephosphorylation|positive regulation of actin filament depolymerization|actin rod assembly|pyridoxal phosphate catabolic process|regulation of cytokinesis|cellular response to ATP|,magnesium ion binding|phosphoserine phosphatase activity|phosphoprotein phosphatase activity|protein binding|hydrolase activity|phosphatase activity|heat shock protein binding|pyridoxal phosphatase activity|protein homodimerization activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000020681,ACE,angiotensin I converting enzyme (peptidyl-dipeptidase A) 1,extracellular region|extracellular space|endosome|plasma membrane|external side of plasma membrane|basal plasma membrane|membrane|integral component of membrane|brush border membrane|vesicle|extracellular vesicular exosome|,kidney development|kidney development|neutrophil mediated immunity|positive regulation of systemic arterial blood pressure|positive regulation of systemic arterial blood pressure|proteolysis|proteolysis|peptide metabolic process|spermatogenesis|regulation of blood pressure|regulation of blood pressure|bradykinin catabolic process|regulation of smooth muscle cell migration|sensory perception of pain|organ regeneration|response to lipopolysaccharide|vasoconstriction|hormone catabolic process|hormone catabolic process|eating behavior|positive regulation of apoptotic process|peptide catabolic process|lung alveolus development|arachidonic acid secretion|positive regulation of inflammatory response|positive regulation of neurogenesis|heart contraction|angiogenesis involved in coronary vascular morphogenesis|negative regulation of calcium ion import|,"actin binding|endopeptidase activity|carboxypeptidase activity|protein binding|drug binding|peptidase activity|metallopeptidase activity|metallopeptidase activity|peptidyl-dipeptidase activity|peptidyl-dipeptidase activity|zinc ion binding|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|chloride ion binding|bradykinin receptor binding|peptide binding|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|metal ion binding|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,-0.3,0.548,10,0.1,0.065,0,0,0,0.832,0,0,-1.6,1.3
ENSMUSG00000003752,ITPKC,"inositol 1,4,5-trisphosphate 3-kinase C",cellular_component|nucleus|cytoplasm|,phosphorylation|,"nucleotide binding|protein binding|calmodulin binding|ATP binding|inositol-1,4,5-trisphosphate 3-kinase activity|kinase activity|transferase activity|",10,-0.1,0.0923,10,0,0,0,0,0,0.832,0,0,-2,0.9
ENSMUSG00000020389,CDKL3,cyclin-dependent kinase-like 3,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|negative regulation of axon extension|negative regulation of axon extension|positive regulation of dendrite morphogenesis|positive regulation of dendrite morphogenesis|dendrite extension|dendrite extension|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.5,0.177,10,0,0,0,0,0,0.832,0,0,-1.1,1.9
ENSMUSG00000001288,RARG,"retinoic acid receptor, gamma",nuclear chromatin|nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|neural tube closure|chondrocyte development|glandular epithelial cell development|retinal pigment epithelium development|growth plate cartilage development|growth plate cartilage chondrocyte growth|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|anterior/posterior pattern specification|anterior/posterior pattern specification|regulation of gene expression|positive regulation of gene expression|embryonic camera-type eye development|regulation of myelination|negative regulation of chondrocyte differentiation|response to retinoic acid|embryonic hindlimb morphogenesis|multicellular organism growth|camera-type eye development|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of programmed cell death|steroid hormone mediated signaling pathway|negative regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic eye morphogenesis|retinoic acid receptor signaling pathway|retinoic acid receptor signaling pathway|reproductive structure development|gland development|retina development in camera-type eye|limb development|limb development|face development|bone development|bone development|bone morphogenesis|bone morphogenesis|epithelium development|trachea cartilage development|prostate gland epithelium morphogenesis|negative regulation of cartilage development|Harderian gland development|cellular response to retinoic acid|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|retinoic acid receptor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|retinoid X receptor binding|,10,-0.1,0.0318,10,0.1,0.213,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000024556,ME2,"malic enzyme 2, NAD(+)-dependent, mitochondrial",mitochondrion|mitochondrion|intracellular membrane-bounded organelle|,malate metabolic process|metabolic process|oxidation-reduction process|,catalytic activity|malic enzyme activity|malate dehydrogenase (decarboxylating) (NAD+) activity|oxaloacetate decarboxylase activity|oxidoreductase activity|metal ion binding|NAD binding|,10,-1.1,0.0563,10,0.7,1.55,0,0,0,0.832,0,0,-1.5,1.9
ENSMUSG00000033470,CYSLTR2,cysteinyl leukotriene receptor 2,plasma membrane|membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cell death|positive regulation of angiogenesis|positive regulation of ERK1 and ERK2 cascade|,cysteinyl leukotriene receptor activity|signal transducer activity|G-protein coupled receptor activity|leukotriene receptor activity|,10,-0.2,0.64,10,0,0,0,0,0,0.832,0,0,-1.7,1.2
ENSMUSG00000003863,PPFIA3,"protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3",cell|cytoplasm|,neurotransmitter secretion|regulation of short-term neuronal synaptic plasticity|,molecular_function|,10,-0.1,0.077,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000026986,HNMT,histamine N-methyltransferase,nucleus|cytoplasm|neuron projection|extracellular vesicular exosome|,regulation of neurotransmitter levels|methylation|,methyltransferase activity|N-methyltransferase activity|transferase activity|histamine N-methyltransferase activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.8,1.3
ENSMUSG00000029864,GSTK1,glutathione S-transferase kappa 1,intracellular|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|peroxisome|membrane|extracellular vesicular exosome|,glutathione metabolic process|oxidation-reduction process|oxidation-reduction process|,glutathione transferase activity|glutathione transferase activity|glutathione peroxidase activity|glutathione peroxidase activity|receptor binding|protein disulfide oxidoreductase activity|transferase activity|,10,1.5,2.89,10,0,0,0,0,0,0.832,0,0,-0.6,3
ENSMUSG00000025041,NT5C2,"5'-nucleotidase, cytosolic II",cellular_component|cytoplasm|,metabolic process|nucleotide metabolic process|dephosphorylation|IMP metabolic process|adenosine metabolic process|,nucleotide binding|catalytic activity|5'-nucleotidase activity|hydrolase activity|metal ion binding|,9,0.5,1.69,10,-0.1,0.0731,0,0,0,0.832,0,0,-0.8,2
ENSMUSG00000039809,GABBR2,"gamma-aminobutyric acid (GABA) B receptor, 2",cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|G-protein coupled receptor heterodimeric complex|neuron projection|synapse|postsynaptic membrane|,signal transduction|G-protein coupled receptor signaling pathway|gamma-aminobutyric acid signaling pathway|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled GABA receptor activity|G-protein coupled GABA receptor activity|protein binding|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000028607,CPT2,carnitine palmitoyltransferase 2,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,lipid metabolic process|fatty acid metabolic process|transport|,"carnitine O-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.1,0.0536,10,0,0,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000022861,DGKG,"diacylglycerol kinase, gamma",plasma membrane|intracellular membrane-bounded organelle|,protein kinase C-activating G-protein coupled receptor signaling pathway|metabolic process|phosphorylation|intracellular signal transduction|,nucleotide binding|NAD+ kinase activity|diacylglycerol kinase activity|calcium ion binding|ATP binding|kinase activity|transferase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000029186,PI4K2B,phosphatidylinositol 4-kinase type 2 beta,cytoplasm|membrane|membrane|,biological_process|phosphorylation|,"nucleotide binding|molecular_function|1-phosphatidylinositol 4-kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|",10,0.1,0.219,10,-0.1,0.085,0,0,0,0.832,0,0,-1.2,1.8
ENSMUSG00000018500,ADORA2B,adenosine A2b receptor,plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|,adenosine receptor signaling pathway|positive regulation of chronic inflammatory response to non-antigenic stimulus|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|positive regulation of cell proliferation|negative regulation of cell proliferation|positive regulation vascular endothelial growth factor production|positive regulation of norepinephrine secretion|positive regulation of steroid biosynthetic process|positive regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|positive regulation of cGMP biosynthetic process|positive regulation of guanylate cyclase activity|cellular response to extracellular stimulus|positive regulation of chemokine production|positive regulation of interleukin-6 production|negative regulation of collagen biosynthetic process|positive regulation of catecholamine secretion|positive regulation of mast cell degranulation|regulation of angiogenesis|positive regulation of vasodilation|relaxation of vascular smooth muscle|,G-protein coupled adenosine receptor activity|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000094393,MUC2,mucin 2,extracellular region|proteinaceous extracellular matrix|inner mucus layer|outer mucus layer|,epithelial cell development|apoptotic process|negative regulation of cell proliferation|maintenance of gastrointestinal epithelium|negative regulation of cell migration|positive regulation of apoptotic process|,protein binding|,10,0,0,10,0.1,0.0692,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000030851,LDHC,lactate dehydrogenase C,nucleus|cytoplasm|cilium|motile cilium|,carbohydrate metabolic process|pyruvate metabolic process|glycolytic process|ATP biosynthetic process|lactate biosynthetic process from pyruvate|lactate oxidation|sperm motility|cellular carbohydrate metabolic process|oxidation-reduction process|,"catalytic activity|L-lactate dehydrogenase activity|protein binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|",10,0.3,0.195,10,0,0,0,0,0,0.832,0,0,-1.3,1.8
ENSMUSG00000026737,PIP4K2A,"phosphatidylinositol-5-phosphate 4-kinase, type II, alpha",nucleus|cytoplasm|plasma membrane|membrane|,phosphorylation|megakaryocyte development|phosphatidylinositol metabolic process|,nucleotide binding|ATP binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-5-phosphate 4-kinase activity|transferase activity|,10,0,0,10,0.1,0.00955,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000021278,AMN,amnionless,extracellular space|membrane|integral component of membrane|apical plasma membrane|endocytic vesicle|apical part of cell|extracellular vesicular exosome|,receptor-mediated endocytosis|multicellular organismal development|excretion|protein localization|cobalamin transport|Golgi to plasma membrane protein transport|,receptor binding|,10,0,0,10,0.5,0.557,0,0,0,0.832,0,0,-0.9,2
ENSMUSG00000046447,CAMK2N1,calcium/calmodulin-dependent protein kinase II inhibitor 1,plasma membrane|postsynaptic density|membrane|cell junction|dendrite|neuron projection|neuronal cell body|synapse|postsynaptic membrane|,negative regulation of protein kinase activity|,protein kinase inhibitor activity|calcium-dependent protein kinase inhibitor activity|protein kinase binding|,9,0.3,0.378,9,0,0,0,0,0,0.832,0,0,-1.2,1.8
ENSMUSG00000062480,ACAT3,acetyl-Coenzyme A acetyltransferase 3,nucleus|nucleolus|cytoplasm|mitochondrion|cytosol|,None,acetyl-CoA C-acetyltransferase activity|transferase activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.3,1.8
ENSMUSG00000001260,GABRG1,"gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1",plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|receptor complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|signal transduction|gamma-aminobutyric acid signaling pathway|synaptic transmission|,GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|GABA receptor binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000075256,CERKL,ceramide kinase-like,nucleolus|cytoplasm|endoplasmic reticulum|Golgi apparatus|,phosphorylation|negative regulation of apoptotic process|,kinase activity|transferase activity|,10,0,0,10,-0.3,0.431,0,0,0,0.832,0,0,-1.8,1
ENSMUSG00000020395,ITK,IL2 inducible T cell kinase,cytoplasm|cell-cell junction|,cytokine production|NK T cell differentiation|NK T cell differentiation|adaptive immune response|immune system process|protein phosphorylation|activation of phospholipase C activity|phosphorylation|peptidyl-tyrosine phosphorylation|interferon-gamma production|interferon-gamma production|interleukin-4 production|interleukin-4 production|intracellular signal transduction|T cell receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.1,0.308,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000031596,SLC7A2,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 2",membrane|integral component of membrane|integral component of membrane|,nitric oxide production involved in inflammatory response|amino acid transmembrane transport|nitric oxide biosynthetic process|transport|amino acid transport|L-amino acid transport|arginine transport|arginine transport|arginine transport|lysine transport|ornithine transport|macrophage activation|regulation of macrophage activation|regulation of inflammatory response|L-alpha-amino acid transmembrane transport|,L-ornithine transmembrane transporter activity|high affinity arginine transmembrane transporter activity|amino acid transmembrane transporter activity|L-amino acid transmembrane transporter activity|L-amino acid transmembrane transporter activity|arginine transmembrane transporter activity|arginine transmembrane transporter activity|arginine transmembrane transporter activity|L-lysine transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000031255,SYTL4,synaptotagmin-like 4,nucleus|cytoplasm|endosome|centrosome|membrane|apical plasma membrane|extrinsic component of membrane|secretory granule|secretory granule membrane|cytoplasmic vesicle|,intracellular protein transport|exocytosis|positive regulation of exocytosis|negative regulation of insulin secretion|positive regulation of protein secretion|multivesicular body sorting pathway|,protein binding|phospholipid binding|zinc ion binding|Rab GTPase binding|neurexin family protein binding|metal ion binding|,10,0,0,10,-0.1,0.0756,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000040314,CTSG,cathepsin G,extracellular space|nucleus|intermediate filament|plasma membrane|membrane|secretory granule|extracellular matrix|extracellular vesicular exosome|,proteolysis|response to lipopolysaccharide|response to lipopolysaccharide|negative regulation of growth of symbiont in host|negative regulation of growth of symbiont in host|positive regulation of immune response|positive regulation of immune response|defense response to Gram-positive bacterium|defense response to fungus|defense response to fungus|neutrophil mediated killing of gram-positive bacterium|,catalytic activity|serine-type endopeptidase activity|heparin binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000038665,DGKI,"diacylglycerol kinase, iota",nucleus|cytoplasm|cytoplasm|guanyl-nucleotide exchange factor complex|perinuclear region of cytoplasm|,phosphorylation|regulation of Rap GTPase activity|negative regulation of catalytic activity|positive regulation of Ras protein signal transduction|,nucleotide binding|diacylglycerol kinase activity|diacylglycerol kinase activity|GTPase inhibitor activity|GTPase inhibitor activity|ATP binding|kinase activity|transferase activity|Ras GTPase binding|,10,-0.2,0.501,10,0.8,1.75,0,0,0,0.832,0,0,-0.8,2
ENSMUSG00000022550,ADCK5,aarF domain containing kinase 5,mitochondrion|membrane|integral component of membrane|,biological_process|phosphorylation|,"molecular_function|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,1,0.993,9,0,0,0,0,0,0.832,0,0,-0.6,2
ENSMUSG00000021456,FBP2,fructose bisphosphatase 2,nucleus|cytoplasm|cell junction|extracellular vesicular exosome|,carbohydrate metabolic process|gluconeogenesis|metabolic process|dephosphorylation|,"catalytic activity|hydrolase activity|fructose 1,6-bisphosphate 1-phosphatase activity|phosphoric ester hydrolase activity|metal ion binding|",10,0,0,10,-0.1,0.12,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000056553,PTPRN2,"protein tyrosine phosphatase, receptor type, N polypeptide 2",cytoplasm|endoplasmic reticulum lumen|membrane|integral component of membrane|secretory granule|secretory granule|cytoplasmic vesicle|terminal bouton|receptor complex|,protein dephosphorylation|dephosphorylation|negative regulation of GTPase activity|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,10,0.1,0.0683,10,-0.1,0.0291,0,0,0,0.832,0,0,-1.8,1.1
ENSMUSG00000041237,PKLR,pyruvate kinase liver and red blood cell,cytosol|extracellular vesicular exosome|,carbohydrate metabolic process|glycolytic process|ATP biosynthetic process|metabolic process|response to heat|response to lithium ion|phosphorylation|cellular response to insulin stimulus|response to ATP|pyruvate biosynthetic process|response to cAMP|response to other organism|,nucleotide binding|magnesium ion binding|catalytic activity|pyruvate kinase activity|pyruvate kinase activity|ATP binding|kinase activity|transferase activity|potassium ion binding|metal ion binding|,10,-0.5,0.671,10,0,0,0,0,0,0.832,0,0,-2,0.9
ENSMUSG00000027261,HAO1,"hydroxyacid oxidase 1, liver",peroxisome|peroxisome|,fatty acid alpha-oxidation|glycolate catabolic process|oxidation-reduction process|,catalytic activity|(S)-2-hydroxy-acid oxidase activity|(S)-2-hydroxy-acid oxidase activity|receptor binding|glycolate oxidase activity|FMN binding|oxidoreductase activity|very-long-chain-(S)-2-hydroxy-acid oxidase activity|long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity|medium-chain-(S)-2-hydroxy-acid oxidase activity|,10,-0.1,0.107,10,0,0,0,0,0,0.832,0,0,-1.8,1.3
ENSMUSG00000024830,RPS6KB2,"ribosomal protein S6 kinase, polypeptide 2",intracellular|nucleus|cytoplasm|,protein phosphorylation|protein phosphorylation|signal transduction|phosphorylation|protein kinase B signaling|positive regulation of translational initiation|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|ribosomal protein S6 kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|peptide binding|",10,-0.4,0.517,10,0.3,0.646,0,0,0,0.832,0,0,-1.7,1.3
ENSMUSG00000039579,GRIN3A,"glutamate receptor ionotropic, NMDA3A",plasma membrane|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|dendrite|neuron projection|neuronal cell body|neuronal cell body|synapse|postsynaptic membrane|postsynaptic membrane|,"transport|ion transport|calcium ion transport|calcium ion transport|dendrite development|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|response to ethanol|rhythmic process|prepulse inhibition|calcium ion transmembrane transport|",ionotropic glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|extracellular-glutamate-gated ion channel activity|calcium channel activity|calcium channel activity|protein binding|glycine binding|neurotransmitter binding|identical protein binding|protein phosphatase 2A binding|,9,0.3,0.215,10,0,0,0,0,0,0.832,0,0,-1,2
ENSMUSG00000035891,CERK,ceramide kinase,cytoplasm|mitochondrion|membrane|integral component of membrane|,ceramide metabolic process|protein kinase C-activating G-protein coupled receptor signaling pathway|metabolic process|phosphorylation|lipid phosphorylation|,nucleotide binding|magnesium ion binding|ceramide kinase activity|NAD+ kinase activity|diacylglycerol kinase activity|ATP binding|kinase activity|transferase activity|,10,0.1,0.363,10,-0.1,0.428,0,0,0,0.832,0,0,-1.5,1.4
ENSMUSG00000056999,IDE,insulin degrading enzyme,extracellular region|extracellular space|nucleus|cytoplasm|mitochondrion|mitochondrion|peroxisome|peroxisomal matrix|cytosol|plasma membrane|cell surface|membrane|cytosolic proteasome complex|,ATP catabolic process|proteolysis|metabolic process|determination of adult lifespan|bradykinin catabolic process|ubiquitin homeostasis|positive regulation of protein oligomerization|hormone catabolic process|cellular protein catabolic process|negative regulation of proteolysis|beta-amyloid metabolic process|protein homooligomerization|protein homotetramerization|protein heterooligomerization|proteolysis involved in cellular protein catabolic process|insulin metabolic process|insulin catabolic process|,nucleotide binding|beta-amyloid binding|glycoprotein binding|catalytic activity|metalloendopeptidase activity|receptor binding|ATP binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|ATPase activity|peptide hormone binding|beta-endorphin binding|peptide binding|protein homodimerization activity|ubiquitin binding|insulin binding|metal ion binding|,10,-0.1,0.211,10,0.6,0.784,0,0,0,0.832,0,0,-0.7,2
ENSMUSG00000034731,DGKH,"diacylglycerol kinase, eta",nucleus|cytoplasm|endosome|nuclear membrane|,protein kinase C-activating G-protein coupled receptor signaling pathway|phosphorylation|diacylglycerol metabolic process|protein oligomerization|,nucleotide binding|diacylglycerol kinase activity|ATP binding|kinase activity|transferase activity|protein homodimerization activity|metal ion binding|,10,0.1,0.0543,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000005980,DNASE1,deoxyribonuclease I,extracellular region|nucleus|extracellular vesicular exosome|,"DNA catabolic process, endonucleolytic|DNA catabolic process|apoptotic process|","actin binding|nuclease activity|endonuclease activity|deoxyribonuclease I activity|deoxyribonuclease activity|hydrolase activity|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|",10,0.3,0.731,10,0,0,0,0,0,0.832,0,0,-1.2,1.7
ENSMUSG00000038642,CTSS,cathepsin S,extracellular space|lysosome|lysosome|cell surface|membrane|intracellular membrane-bounded organelle|,proteolysis|collagen catabolic process|basement membrane disassembly|basement membrane disassembly|bone resorption|positive regulation of inflammatory response|proteolysis involved in cellular protein catabolic process|proteolysis involved in cellular protein catabolic process|regulation of sensory perception of pain|,fibronectin binding|cysteine-type endopeptidase activity|collagen binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|laminin binding|proteoglycan binding|,10,0.2,0.0131,10,-0.1,0.211,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000018547,PIP4K2B,"phosphatidylinositol-5-phosphate 4-kinase, type II, beta",nucleus|cytoplasm|endoplasmic reticulum|plasma membrane|membrane|,phosphorylation|phosphatidylinositol metabolic process|phosphatidylinositol phosphorylation|,nucleotide binding|protein binding|ATP binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|1-phosphatidylinositol-5-phosphate 4-kinase activity|transferase activity|,10,0,0,10,0.1,0.0546,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000009772,NUAK2,"NUAK family, SNF1-like kinase, 2",None,protein phosphorylation|apoptotic process|phosphorylation|actin cytoskeleton organization|cellular response to glucose starvation|negative regulation of apoptotic process|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-1.1,1.77,10,0,0,0,0,0,0.832,0,0,-2,0.8
ENSMUSG00000037012,HK1,hexokinase 1,mitochondrion|mitochondrion|mitochondrial outer membrane|cytosol|cytosol|caveola|cilium|membrane|protein complex|membrane raft|sperm principal piece|,cellular glucose homeostasis|response to ischemia|carbohydrate metabolic process|glycolytic process|glycolytic process|protein phosphorylation|metabolic process|regulation of anion channel activity|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|peptidyl-tyrosine phosphorylation|negative regulation of apoptotic process|protein autophosphorylation|carbohydrate phosphorylation|carbohydrate phosphorylation|glucose 6-phosphate metabolic process|glucose 6-phosphate metabolic process|canonical glycolysis|,"nucleotide binding|catalytic activity|glucokinase activity|glucokinase activity|glucokinase activity|hexokinase activity|hexokinase activity|hexokinase activity|protein kinase activity|protein binding|ATP binding|glucose binding|fructokinase activity|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|mannokinase activity|protein complex binding|protein homodimerization activity|",10,0,0,10,-0.3,1.26,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000046707,CSNK2A2,"casein kinase 2, alpha prime polypeptide",nucleus|protein kinase CK2 complex|PcG protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|cell cycle|Wnt signaling pathway|phosphorylation|regulation of cell cycle|mitotic spindle checkpoint|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein N-terminus binding|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.7
ENSMUSG00000042724,MAP3K9,mitogen-activated protein kinase kinase kinase 9,None,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|response to stress|cell death|phosphorylation|positive regulation of apoptotic process|protein autophosphorylation|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.127,10,0.2,0.602,0,0,0,0.832,0,0,-1.3,1.6
ENSMUSG00000024197,PLIN3,perilipin 3,cytoplasm|endosome|lipid particle|membrane|membrane|intracellular membrane-bounded organelle|,transport|,None,10,0,0,10,0.1,0.168,0,0,0,0.832,0,0,-1.8,1.3
ENSMUSG00000043017,PTGIR,prostaglandin I receptor (IP),cytosol|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|negative regulation of platelet-derived growth factor receptor signaling pathway|positive regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|response to lipopolysaccharide|positive regulation of cAMP-mediated signaling|positive regulation of cAMP-mediated signaling|negative regulation of smooth muscle cell proliferation|negative regulation of smooth muscle cell proliferation|,signal transducer activity|G-protein coupled receptor activity|,10,0.5,0.661,10,0,0,0,0,0,0.832,0,0,-1.1,1.8
ENSMUSG00000052298,CDC42SE2,CDC42 small effector 2,cytoplasm|cytoskeleton|plasma membrane|membrane|cell projection|extracellular vesicular exosome|,phagocytosis|regulation of cell shape|regulation of signal transduction|,structural molecule activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.4,1.6
ENSMUSG00000011884,GLTP,glycolipid transfer protein,cytoplasm|extracellular vesicular exosome|,transport|lipid transport|glycolipid transport|,lipid binding|glycolipid transporter activity|glycolipid binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000006641,SLC5A6,"solute carrier family 5 (sodium-dependent vitamin transporter), member 6",vesicle membrane|membrane|integral component of membrane|brush border membrane|,transport|ion transport|sodium ion transport|biotin transport|pantothenate transmembrane transport|sodium ion transmembrane transport|transmembrane transport|,transporter activity|sodium-dependent multivitamin transmembrane transporter activity|symporter activity|,10,0.1,0.0235,10,-1.1,3.06,0,0,0,0.832,0,0,-2,0.8
ENSMUSG00000028128,F3,coagulation factor III,extracellular space|cytoplasm|cell surface|membrane|integral component of membrane|extracellular matrix|extracellular vesicular exosome|,positive regulation of endothelial cell proliferation|activation of plasma proteins involved in acute inflammatory response|activation of cysteine-type endopeptidase activity involved in apoptotic process|blood coagulation|hemostasis|positive regulation of platelet-derived growth factor receptor signaling pathway|positive regulation of smooth muscle cell migration|positive regulation of angiogenesis|positive regulation of protein kinase B signaling|,protease binding|phospholipid binding|,10,0.1,0.215,10,-0.1,0.0232,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000005251,RIPK4,receptor-interacting serine-threonine kinase 4,nucleus|cytoplasm|cytoplasm|membrane|,morphogenesis of an epithelium|protein phosphorylation|phosphorylation|positive regulation of NF-kappaB transcription factor activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.2,1.9
ENSMUSG00000040466,BLVRB,biliverdin reductase B (flavin reductase (NADPH)),nucleus|cytoplasm|cytosol|plasma membrane|extracellular vesicular exosome|,heme catabolic process|oxidation-reduction process|,biliverdin reductase activity|oxidoreductase activity|riboflavin reductase (NADPH) activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000040197,CD209E,CD209e antigen,membrane|integral component of membrane|extracellular vesicular exosome|,endocytosis|biological_process|,mannose binding|carbohydrate binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.4,1.8
ENSMUSG00000033998,KCNK1,"potassium channel, subfamily K, member 1",cytoplasm|endosome|membrane|integral component of membrane|apical plasma membrane|brush border membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|potassium channel activity|protein binding|,10,0.3,0.374,10,0,0,0,0,0,0.832,0,0,-1.9,1.1
ENSMUSG00000028416,BAG1,BCL2-associated athanogene 1,nucleus|nucleus|cytoplasm|mitochondrion|cytosol|cytosol|perinuclear region of cytoplasm|,negative regulation of protein phosphorylation|apoptotic process|neuron differentiation|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of transcription from RNA polymerase II promoter|chaperone cofactor-dependent protein refolding|protein localization to mitochondrion|negative regulation of motor neuron apoptotic process|,protein binding|chaperone binding|phosphoprotein binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000040118,CACNA2D1,"calcium channel, voltage-dependent, alpha2/delta subunit 1",voltage-gated calcium channel complex|membrane|integral component of membrane|sarcoplasmic reticulum|T-tubule|extracellular vesicular exosome|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|regulation of calcium ion transport|regulation of calcium ion transport|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000038319,KCNH2,"potassium voltage-gated channel, subfamily H (eag-related), member 2",nuclear envelope|cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|voltage-gated potassium channel complex|cell surface|membrane|integral component of membrane|,phosphorelay signal transduction system|transport|ion transport|potassium ion transport|signal transduction|regulation of ion transmembrane transport|cellular response to drug|regulation of membrane potential|regulation of membrane potential|protein heterooligomerization|potassium ion homeostasis|transmembrane transport|cardiac muscle contraction|regulation of membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|potassium ion export|potassium ion transmembrane transport|potassium ion transmembrane transport|ventricular cardiac muscle cell action potential|membrane depolarization during action potential|membrane repolarization during action potential|membrane repolarization during cardiac muscle cell action potential|regulation of heart rate by cardiac conduction|regulation of heart rate by cardiac conduction|regulation of potassium ion transmembrane transport|negative regulation of potassium ion transmembrane transport|positive regulation of potassium ion transmembrane transport|negative regulation of potassium ion export|,phosphorelay sensor kinase activity|signal transducer activity|ion channel activity|inward rectifier potassium channel activity|inward rectifier potassium channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|ubiquitin protein ligase binding|identical protein binding|protein homodimerization activity|voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|,10,0.1,0.0246,10,0,0,0,0,0,0.832,0,0,-1,2
ENSMUSG00000039166,AKAP7,A kinase (PRKA) anchor protein 7,nucleus|cytoplasm|cytosol|plasma membrane|membrane|apical plasma membrane|lateral plasma membrane|sarcoplasmic reticulum|T-tubule|protein complex|exocytic vesicle|,transmembrane receptor protein serine/threonine kinase signaling pathway|protein localization|regulation of protein kinase A signaling|regulation of membrane repolarization|cellular response to cAMP|positive regulation of potassium ion transmembrane transport|positive regulation of delayed rectifier potassium channel activity|,nucleotide binding|catalytic activity|protein binding|protein C-terminus binding|AMP binding|protein kinase binding|protein domain specific binding|protein complex scaffold|protein kinase A regulatory subunit binding|protein kinase A regulatory subunit binding|protein kinase A binding|protein kinase A binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000018339,GPX3,glutathione peroxidase 3,extracellular region|extracellular space|extracellular vesicular exosome|,glutathione metabolic process|response to oxidative stress|hydrogen peroxide catabolic process|hydrogen peroxide catabolic process|protein homotetramerization|oxidation-reduction process|,peroxidase activity|glutathione peroxidase activity|glutathione peroxidase activity|selenium binding|oxidoreductase activity|glutathione binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.9,1
ENSMUSG00000059089,FCGR4,"Fc receptor, IgG, low affinity IV",external side of plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,NK T cell proliferation|regulation of sensory perception of pain|cellular response to lipopolysaccharide|,None,10,0.4,0.988,10,0,0,0,0,0,0.832,0,0,-1.2,1.7
ENSMUSG00000033022,CDO1,"cysteine dioxygenase 1, cytosolic",cytosol|,lactation|response to organonitrogen compound|L-cysteine catabolic process|L-cysteine catabolic process to taurine|taurine metabolic process|response to glucagon|response to amino acid|response to ethanol|L-cysteine metabolic process|response to glucocorticoid|response to cAMP|oxidation-reduction process|,iron ion binding|ferrous iron binding|oxidoreductase activity|cysteine dioxygenase activity|cysteine dioxygenase activity|metal ion binding|dioxygenase activity|,10,0,0,10,-0.1,0.0457,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000028223,DECR1,"2,4-dienoyl CoA reductase 1, mitochondrial",nucleus|cytoplasm|mitochondrion|mitochondrion|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|protein homotetramerization|oxidation-reduction process|,"2,4-dienoyl-CoA reductase (NADPH) activity|oxidoreductase activity|NADPH binding|",10,0,0,10,0.1,0.186,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000074939,CHRM5,"cholinergic receptor, muscarinic 5",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,gastric acid secretion|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled acetylcholine receptor signaling pathway|synaptic transmission|dopamine transport|transmission of nerve impulse|regulation of phosphatidylinositol dephosphorylation|chloride transmembrane transport|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled acetylcholine receptor activity|extracellular-glycine-gated chloride channel activity|,10,0.1,0.0899,10,0,0,0,0,0,0.832,0,0,-1.3,1.7
ENSMUSG00000026596,ABL2,"v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)",phagocytic cup|cytoplasm|cytoskeleton|actin cytoskeleton|cytoplasmic membrane-bounded vesicle|,"protein phosphorylation|phagocytosis|actin filament organization|cell adhesion|epidermal growth factor receptor signaling pathway|learning|positive regulation of neuron projection development|phosphorylation|neuron remodeling|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cerebellum morphogenesis|actin cytoskeleton organization|positive regulation of I-kappaB kinase/NF-kappaB signaling|alpha-beta T cell differentiation|platelet-derived growth factor receptor signaling pathway|neuromuscular process controlling balance|actin filament bundle assembly|positive regulation of oxidoreductase activity|Bergmann glial cell differentiation|positive regulation of ERK1 and ERK2 cascade|cellular response to retinoic acid|positive regulation of interleukin-2 secretion|positive regulation of interferon-gamma secretion|regulation of extracellular matrix organization|positive regulation of Wnt signaling pathway, planar cell polarity pathway|","nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|manganese ion binding|manganese ion binding|metal ion binding|",10,0,0,10,-1.2,2.32,0,0,0,0.832,0,0,-2,0.6
ENSMUSG00000025271,PFKFB1,"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex|","fructose metabolic process|fructose 2,6-bisphosphate metabolic process|metabolic process|phosphorylation|dephosphorylation|positive regulation of glucokinase activity|carbohydrate phosphorylation|","nucleotide binding|catalytic activity|6-phosphofructo-2-kinase activity|fructose-2,6-bisphosphate 2-phosphatase activity|ATP binding|kinase activity|transferase activity|hydrolase activity|kinase binding|identical protein binding|fructose-6-phosphate binding|",10,-0.1,0.0428,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000025701,ALOX5,arachidonate 5-lipoxygenase,extracellular space|nucleus|nucleus|nuclear envelope|nuclear envelope lumen|cytoplasm|cytosol|membrane|nuclear matrix|dendrite|nuclear membrane|sarcolemma|,acute inflammatory response|leukotriene production involved in inflammatory response|leukotriene metabolic process|inflammatory response|sensory perception of pain|arachidonic acid metabolic process|leukotriene biosynthetic process|leukotriene biosynthetic process|leukotriene biosynthetic process|lipoxygenase pathway|positive regulation of vasoconstriction|oxidation-reduction process|,"arachidonate 5-lipoxygenase activity|iron ion binding|protein binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|metal ion binding|dioxygenase activity|",10,-0.1,0.112,10,0.1,0.256,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000027330,CDC25B,cell division cycle 25B,spindle pole|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|centrosome|cytoskeleton|,mitotic M phase|oocyte maturation|protein phosphorylation|protein dephosphorylation|cell cycle|mitotic nuclear division|female meiosis I|positive regulation of cytokinesis|positive regulation of protein kinase activity|positive regulation of mitotic cell cycle|cell division|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|protein kinase binding|,10,0,0,10,-0.1,0.0234,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000008932,SLC1A7,"solute carrier family 1 (glutamate transporter), member 7",membrane|integral component of membrane|,transport|dicarboxylic acid transport|,symporter activity|sodium:dicarboxylate symporter activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000032257,ANKK1,ankyrin repeat and kinase domain containing 1,cellular_component|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.5
ENSMUSG00000018659,PNPO,pyridoxine 5'-phosphate oxidase,extracellular vesicular exosome|,pyridoxine biosynthetic process|pyridoxal phosphate biosynthetic process|oxidation-reduction process|,"pyridoxamine-phosphate oxidase activity|FMN binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-NH2 group of donors|",10,-0.2,0.467,10,0,0,0,0,0,0.832,0,0,-1.8,1.2
ENSMUSG00000028841,CNKSR1,connector enhancer of kinase suppressor of Ras 1,cell cortex|,Ras protein signal transduction|Rho protein signal transduction|phosphorylation|,"kinase activity|transferase activity|protein binding, bridging|",8,0,0,9,0.7,2.3,0,0,0,0.832,0,0,-0.7,2
ENSMUSG00000028199,CRYZ,"crystallin, zeta",cytoplasm|Golgi apparatus|cytosol|intracellular membrane-bounded organelle|extracellular vesicular exosome|,xenobiotic catabolic process|protein homotetramerization|oxidation-reduction process|,RNA binding|mRNA 3'-UTR binding|NADPH:quinone reductase activity|zinc ion binding|oxidoreductase activity|NADP binding|NADPH binding|,10,0.1,0.504,10,0,0,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000022791,TNK2,"tyrosine kinase, non-receptor, 2",nucleus|nucleus|cytoplasm|endosome|plasma membrane|plasma membrane|coated pit|membrane|membrane|cell junction|clathrin-coated vesicle|axon|dendrite|growth cone|cytoplasmic vesicle|neuronal cell body|Grb2-EGFR complex|,protein phosphorylation|endocytosis|phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|regulation of clathrin-mediated endocytosis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|epidermal growth factor receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|WW domain binding|",10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000032607,AMT,aminomethyltransferase,cytoplasm|mitochondrion|,glycine catabolic process|methylation|,aminomethyltransferase activity|methyltransferase activity|transaminase activity|transferase activity|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.4,1.7
ENSMUSG00000002985,APOE,apolipoprotein E,extracellular region|extracellular space|extracellular space|nucleus|nuclear envelope|cytoplasm|lysosome|endosome|early endosome|late endosome|endoplasmic reticulum|Golgi apparatus|microtubule|plasma membrane|cell surface|membrane|dendrite|extrinsic component of external side of plasma membrane|very-low-density lipoprotein particle|low-density lipoprotein particle|low-density lipoprotein particle|intermediate-density lipoprotein particle|high-density lipoprotein particle|discoidal high-density lipoprotein particle|chylomicron|neuronal cell body|extracellular vesicular exosome|blood microparticle|,negative regulation of endothelial cell proliferation|response to dietary excess|lipid metabolic process|triglyceride metabolic process|cholesterol catabolic process|transport|lipid transport|cellular calcium ion homeostasis|receptor-mediated endocytosis|response to oxidative stress|G-protein coupled receptor signaling pathway|nitric oxide mediated signal transduction|aging|cholesterol metabolic process|cholesterol metabolic process|regulation of gene expression|negative regulation of platelet activation|positive regulation of cholesterol esterification|positive regulation of cholesterol esterification|positive regulation of cholesterol efflux|long-chain fatty acid transport|protein import|cGMP-mediated signaling|negative regulation of blood coagulation|positive regulation of cGMP biosynthetic process|regulation of Cdc42 protein signal transduction|positive regulation of low-density lipoprotein particle receptor catabolic process|cholesterol efflux|cholesterol efflux|cholesterol efflux|phospholipid efflux|very-low-density lipoprotein particle remodeling|very-low-density lipoprotein particle remodeling|low-density lipoprotein particle remodeling|high-density lipoprotein particle remodeling|high-density lipoprotein particle assembly|chylomicron remnant clearance|high-density lipoprotein particle clearance|very-low-density lipoprotein particle clearance|lipoprotein metabolic process|lipoprotein metabolic process|lipoprotein metabolic process|lipoprotein biosynthetic process|lipoprotein catabolic process|vasodilation|cholesterol homeostasis|cholesterol homeostasis|cholesterol homeostasis|positive regulation of catalytic activity|negative regulation of MAP kinase activity|negative regulation of neuron apoptotic process|negative regulation of blood vessel endothelial cell migration|reverse cholesterol transport|negative regulation of cholesterol biosynthetic process|positive regulation of axon extension|positive regulation of lipid biosynthetic process|artery morphogenesis|negative regulation of inflammatory response|positive regulation of nitric-oxide synthase activity|positive regulation of membrane protein ectodomain proteolysis|negative regulation of lipid biosynthetic process|maintenance of location in cell|lipid homeostasis|fatty acid homeostasis|positive regulation of dendritic spine development|negative regulation of dendritic spine development|cardiovascular system development|negative regulation of cholesterol efflux|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|N-methyl-D-aspartate receptor clustering|regulation of beta-amyloid clearance|regulation of neuron death|negative regulation of neuron death|positive regulation of neuron death|negative regulation of postsynaptic membrane organization|positive regulation of postsynaptic membrane organization|negative regulation of presynaptic membrane organization|positive regulation of presynaptic membrane organization|positive regulation of beta-amyloid formation|negative regulation of beta-amyloid formation|regulation of tau-protein kinase activity|negative regulation of dendritic spine maintenance|positive regulation of dendritic spine maintenance|positive regulation of phospholipid efflux|positive regulation of neurofibrillary tangle assembly|negative regulation of phospholipid efflux|negative regulation of lipid transport across blood brain barrier|positive regulation of lipid transport across blood brain barrier|,beta-amyloid binding|receptor binding|lipid transporter activity|protein binding|phospholipid binding|heparin binding|lipid binding|antioxidant activity|cholesterol transporter activity|identical protein binding|protein homodimerization activity|hydroxyapatite binding|metal chelating activity|tau protein binding|low-density lipoprotein particle receptor binding|phosphatidylcholine-sterol O-acyltransferase activator activity|phosphatidylcholine-sterol O-acyltransferase activator activity|very-low-density lipoprotein particle receptor binding|lipoprotein particle binding|,10,0.2,0.54,10,0,0,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000074264,AMY1,"amylase 1, salivary",extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|,carbohydrate metabolic process|metabolic process|carbohydrate catabolic process|,"catalytic activity|alpha-amylase activity|calcium ion binding|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|chloride ion binding|cation binding|metal ion binding|",10,0,0,10,-0.6,0.337,0,0,0,0.832,0,0,-1.9,0.9
ENSMUSG00000052026,SLC6A7,"solute carrier family 6 (neurotransmitter transporter, L-proline), member 7",membrane|integral component of membrane|,transport|neurotransmitter transport|amino acid transport|,neurotransmitter:sodium symporter activity|symporter activity|,10,0,0,10,0.1,0.0527,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000025175,FN3K,fructosamine 3 kinase,cytosol|,phosphorylation|fructosamine metabolic process|,"phosphofructokinase activity|phosphorylase kinase regulator activity|cobinamide kinase activity|phytol kinase activity|kinase activity|phosphatidylinositol phosphate kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phenol kinase activity|cyclin-dependent protein kinase activating kinase regulator activity|fructosamine-3-kinase activity|inositol tetrakisphosphate 2-kinase activity|heptose 7-phosphate kinase activity|aminoglycoside phosphotransferase activity|phosphatidylinositol 3-kinase activity|eukaryotic elongation factor-2 kinase regulator activity|eukaryotic elongation factor-2 kinase activator activity|LPPG:FO 2-phospho-L-lactate transferase activity|cytidine kinase activity|glycerate 2-kinase activity|(S)-lactate 2-kinase activity|phosphoserine:homoserine phosphotransferase activity|L-seryl-tRNA(Sec) kinase activity|phosphocholine transferase activity|polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide kinase activity|GTP-dependent polynucleotide kinase activity|farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|geraniol kinase activity|geranylgeraniol kinase activity|CTP:geranylgeraniol kinase activity|prenol kinase activity|1-phosphatidylinositol-5-kinase activity|1-phosphatidylinositol-3-phosphate 4-kinase activity|phosphatidylinositol-3,4-bisphosphate 5-kinase activity|phosphatidylinositol bisphosphate kinase activity|inositol-3,4,6-trisphosphate 1-kinase activity|inositol 5-diphosphate pentakisphosphate 5-kinase activity|inositol diphosphate tetrakisphosphate kinase activity|",10,0.2,0.894,10,0,0,0,0,0,0.832,0,0,-1.3,1.7
ENSMUSG00000039458,MTMR12,myotubularin related protein 12,cellular_component|cytoplasm|,biological_process|dephosphorylation|,molecular_function|phosphatase activity|,10,0.2,0.4,10,0,0,0,0,0,0.832,0,0,-1.5,1.5
ENSMUSG00000015568,LPL,lipoprotein lipase,extracellular region|extracellular space|extracellular space|plasma membrane|cell surface|membrane|extracellular matrix|anchored component of membrane|very-low-density lipoprotein particle|chylomicron|extracellular vesicular exosome|,lipid metabolic process|fatty acid biosynthetic process|positive regulation of macrophage derived foam cell differentiation|positive regulation of cholesterol storage|positive regulation of sequestering of triglyceride|lipid catabolic process|triglyceride biosynthetic process|triglyceride catabolic process|triglyceride catabolic process|very-low-density lipoprotein particle remodeling|triglyceride homeostasis|,catalytic activity|lipoprotein lipase activity|lipoprotein lipase activity|triglyceride lipase activity|triglyceride lipase activity|receptor binding|protein binding|heparin binding|hydrolase activity|triglyceride binding|apolipoprotein binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.7
ENSMUSG00000005533,IGF1R,insulin-like growth factor I receptor,plasma membrane|caveola|membrane|integral component of membrane|neuron projection|intracellular membrane-bounded organelle|receptor complex|,protein phosphorylation|immune response|transmembrane receptor protein tyrosine kinase signaling pathway|axonogenesis|brain development|epidermis development|organ morphogenesis|negative regulation of muscle cell apoptotic process|phosphorylation|establishment of cell polarity|male sex determination|positive regulation of cell migration|mammary gland development|exocrine pancreas development|neuron projection development|positive regulation of cytokinesis|peptidyl-tyrosine autophosphorylation|peptidyl-tyrosine autophosphorylation|negative regulation of apoptotic process|negative regulation of MAPK cascade|positive regulation of MAPK cascade|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of DNA replication|positive regulation of mitosis|regulation of JNK cascade|protein autophosphorylation|insulin-like growth factor receptor signaling pathway|insulin-like growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of DNA metabolic process|protein tetramerization|protein heterooligomerization|inactivation of MAPKK activity|positive regulation of protein kinase B signaling|negative regulation of protein kinase B signaling|prostate gland epithelium morphogenesis|positive regulation of steroid hormone biosynthetic process|,"nucleotide binding|G-protein alpha-subunit binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|insulin-like growth factor-activated receptor activity|insulin receptor binding|protein binding|insulin-like growth factor binding|insulin-like growth factor binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|insulin-like growth factor I binding|identical protein binding|phosphatidylinositol 3-kinase binding|insulin binding|insulin receptor substrate binding|",10,-0.1,0.204,10,0.1,0.182,0,0,0,0.832,0,0,-1.1,1.8
ENSMUSG00000073940,HBB-BT,"hemoglobin, beta adult t chain",hemoglobin complex|haptoglobin-hemoglobin complex|extracellular vesicular exosome|blood microparticle|,None,peroxidase activity|oxygen binding|oxygen binding|hemoglobin binding|haptoglobin binding|hemoglobin alpha binding|hemoglobin beta binding|,10,0.1,0.256,10,-0.7,0.721,0,0,0,0.832,0,0,-2,0.9
ENSMUSG00000041046,RAMP3,receptor (calcitonin) activity modifying protein 3,intracellular|lysosome|plasma membrane|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|,"positive regulation of receptor recycling|transport|calcium ion transport|intracellular protein transport|signal transduction|G-protein coupled receptor signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|protein transport|receptor internalization|negative regulation of transcription, DNA-templated|cellular response to estradiol stimulus|protein localization to plasma membrane|G-protein coupled receptor signaling pathway involved in heart process|positive regulation of establishment of protein localization to plasma membrane|",receptor activity|protein transporter activity|coreceptor activity|coreceptor activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000032500,DCLK3,doublecortin-like kinase 3,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0.3,0.0773,9,0.1,0.062,0,0,0,0.832,0,0,-1.4,1.8
ENSMUSG00000032773,CHRM1,"cholinergic receptor, muscarinic 1, CNS",plasma membrane|integral component of plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|asymmetric synapse|axon terminus|synapse|postsynaptic membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled acetylcholine receptor signaling pathway|neuromuscular synaptic transmission|regulation of locomotion|positive regulation of ion transport|saliva secretion|cognition|positive regulation of intracellular protein transport|,signal transducer activity|G-protein coupled receptor activity|drug binding|G-protein coupled acetylcholine receptor activity|,10,0,0,10,0.2,0.664,0,0,0,0.832,0,0,-1.3,1.7
ENSMUSG00000027470,MYLK2,"myosin, light polypeptide kinase 2, skeletal muscle",nucleus|cytoplasm|synaptic vesicle|postsynaptic density|dendrite|neuronal cell body|terminal bouton|dendritic spine|,protein phosphorylation|water transport|regulation of muscle contraction|striated muscle contraction|neuromuscular synaptic transmission|neuromuscular synaptic transmission|positive regulation of gene expression|skeletal muscle satellite cell differentiation|phosphorylation|peptidyl-threonine phosphorylation|positive regulation of fast-twitch skeletal muscle fiber contraction|regulation of muscle filament sliding|skeletal muscle cell differentiation|skeletal muscle cell differentiation|regulation of MAPK cascade|protein autophosphorylation|regulation of neuronal synaptic plasticity|synaptic vesicle transport|positive regulation of cellular component movement|regulation of cell cycle|cardiac muscle cell differentiation|cardiac muscle tissue morphogenesis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|myosin light chain kinase activity|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|myosin light chain binding|",10,-0.1,0.211,10,0.1,0.0846,0,0,0,0.832,0,0,-1.6,1.4
ENSMUSG00000074183,GSTA1,"glutathione S-transferase, alpha 1 (Ya)",None,glutathione metabolic process|,glutathione transferase activity|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.6,1.6
ENSMUSG00000041078,GRID1,"glutamate receptor, ionotropic, delta 1",plasma membrane|ionotropic glutamate receptor complex|membrane|integral component of membrane|cell junction|dendrite|synapse|postsynaptic membrane|extracellular vesicular exosome|,"transport|ion transport|ion transmembrane transport|social behavior|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|",receptor activity|ionotropic glutamate receptor activity|transporter activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.6,1.5
ENSMUSG00000035561,ALDH1B1,"aldehyde dehydrogenase 1 family, member B1",nucleus|mitochondrion|mitochondrion|intracellular membrane-bounded organelle|,metabolic process|oxidation-reduction process|,"aldehyde dehydrogenase (NAD) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|",10,1,2.4,10,-0.1,0.387,0,0,0,0.832,0,0,-0.6,2
ENSMUSG00000059895,PTP4A3,protein tyrosine phosphatase 4a3,endosome|plasma membrane|membrane|,protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,9,-0.2,0.97,9,0.4,1.64,0,0,0,0.832,0,0,-1.2,1.8
ENSMUSG00000027555,CAR13,carbonic anhydrase 13,cytosol|myelin sheath|,one-carbon metabolic process|,carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,0,0,10,0.1,0.195,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000056973,CES1D,carboxylesterase 1D,cytoplasm|endoplasmic reticulum|endoplasmic reticulum lumen|lipid particle|cytosol|,lipid metabolic process|acyl-CoA metabolic process|response to toxic substance|lipid catabolic process|lipid catabolic process|short-chain fatty acid catabolic process|epithelial cell differentiation|very-low-density lipoprotein particle assembly|acylglycerol catabolic process|,sterol esterase activity|triglyceride lipase activity|hydrolase activity|fatty-acyl-ethyl-ester synthase activity|carboxylic ester hydrolase activity|carboxylic ester hydrolase activity|carboxylic ester hydrolase activity|carboxylic ester hydrolase activity|,9,0,0,9,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000025396,HSD17B6,hydroxysteroid (17-beta) dehydrogenase 6,endosome|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,lipid metabolic process|metabolic process|steroid metabolic process|oxidation-reduction process|,estradiol 17-beta-dehydrogenase activity|retinol dehydrogenase activity|oxidoreductase activity|testosterone dehydrogenase (NAD+) activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.7,1.4
ENSMUSG00000027605,ACSS2,acyl-CoA synthetase short-chain family member 2,nucleus|cytoplasm|cytoplasm|intracellular membrane-bounded organelle|,acetyl-CoA biosynthetic process|metabolic process|lipid biosynthetic process|acetate biosynthetic process|propionate biosynthetic process|,nucleotide binding|catalytic activity|acetate-CoA ligase activity|acetate-CoA ligase activity|ATP binding|ligase activity|,10,0,0,10,0,0,0,0,0,0.832,0,0,-1.5,1.6
ENSMUSG00000028671,GALE,"galactose-4-epimerase, UDP",extracellular vesicular exosome|,carbohydrate metabolic process|galactose metabolic process|galactose catabolic process|,"catalytic activity|UDP-glucose 4-epimerase activity|UDP-glucose 4-epimerase activity|isomerase activity|racemase and epimerase activity, acting on carbohydrates and derivatives|protein homodimerization activity|coenzyme binding|",10,2.2,158,10,1.7,247,2,402,402,1.00E-05,1,1,1.6,2.5
ENSMUSG00000091512,LAMTOR3,"late endosomal/lysosomal adaptor, MAPK and MTOR activator 3",late endosome|extracellular vesicular exosome|Ragulator complex|,activation of MAPKK activity|positive regulation of TOR signaling|cellular protein localization|positive regulation of GTPase activity|cellular response to amino acid stimulus|,guanyl-nucleotide exchange factor activity|kinase activator activity|protein complex scaffold|,10,1.7,88.3,10,1.5,185,1.6,272,272,1.00E-05,1,1,1.3,2
ENSMUSG00000020152,ACTR2,ARP2 actin-related protein 2,intracellular|cell|cytoplasm|cytoplasm|cytoskeleton|cell cortex|membrane|actin cap|cell projection|extracellular vesicular exosome|,establishment or maintenance of cell polarity|asymmetric cell division|meiotic chromosome movement towards spindle pole|cytoplasmic transport|actin cytoskeleton organization|meiotic cytokinesis|cilium assembly|meiotic cell cycle|spindle localization|,nucleotide binding|molecular_function|actin binding|ATP binding|,8,1.9,52.8,9,1.4,124,1.4,175,175,1.00E-05,1,1,1.1,2.2
ENSMUSG00000022551,CYC1,cytochrome c-1,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|membrane|integral component of membrane|respiratory chain|,transport|response to glucagon|oxidation-reduction process|,iron ion binding|electron carrier activity|heme binding|metal ion binding|,9,1.6,52.8,8,1.2,86.2,1.5,137,137,1.00E-05,1,1,1,2.3
ENSMUSG00000029465,ARPC3,"actin related protein 2/3 complex, subunit 3",cytoplasm|cytoskeleton|Arp2/3 protein complex|membrane|lamellipodium|cell projection|extracellular vesicular exosome|,regulation of actin filament polymerization|Arp2/3 complex-mediated actin nucleation|,actin binding|,10,1.9,54.1,10,1.2,87,1.7,137,137,1.00E-05,1,1,1.2,2.5
ENSMUSG00000001416,CCT3,"chaperonin containing Tcp1, subunit 3 (gamma)",zona pellucida receptor complex|cytoplasm|chaperonin-containing T-complex|microtubule|plasma membrane|cell body|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|,nucleotide binding|protein binding|ATP binding|poly(A) RNA binding|unfolded protein binding|,8,1.6,34,8,1.4,103,1.5,137,137,1.00E-05,1,1,1.2,2.2
ENSMUSG00000039515,PPP2R4,"protein phosphatase 2A activator, regulatory subunit B",protein phosphatase type 2A complex|nucleus|nucleus|cytoplasm|cytoplasm|calcium channel complex|extracellular vesicular exosome|,protein peptidyl-prolyl isomerization|ATP catabolic process|protein folding|mitotic spindle organization in nucleus|negative regulation of phosphoprotein phosphatase activity|positive regulation of phosphoprotein phosphatase activity|positive regulation of protein dephosphorylation|negative regulation of protein dephosphorylation|positive regulation of apoptotic process|positive regulation of catalytic activity|regulation of phosphoprotein phosphatase activity|,nucleotide binding|peptidyl-prolyl cis-trans isomerase activity|receptor binding|ATP binding|protein tyrosine phosphatase activator activity|protein tyrosine phosphatase activator activity|protein phosphatase type 2A regulator activity|protein phosphatase type 2A regulator activity|isomerase activity|ATPase activity|phosphatase activator activity|protein homodimerization activity|protein phosphatase 2A binding|,10,1.1,40.4,10,1.1,89.2,1.1,129,129,1.00E-05,1,1,0.9,1.5
ENSMUSG00000001891,UGP2,UDP-glucose pyrophosphorylase 2,nucleus|cytoplasm|extracellular vesicular exosome|,UDP-glucose metabolic process|metabolic process|glucose 1-phosphate metabolic process|,UTP:glucose-1-phosphate uridylyltransferase activity|glucose binding|transferase activity|nucleotidyltransferase activity|pyrimidine ribonucleotide binding|metal ion binding|uridylyltransferase activity|,10,1.6,52.6,10,1.3,60.2,1.5,112,112,1.00E-05,1,1,1.1,2
ENSMUSG00000019907,PPP1R12A,"protein phosphatase 1, regulatory (inhibitor) subunit 12A",kinetochore|cytoplasm|centrosome|actin cytoskeleton|contractile fiber|PTW/PP1 phosphatase complex|,protein dephosphorylation|protein dephosphorylation|mitotic nuclear division|regulation of cell adhesion|regulation of myosin-light-chain-phosphatase activity|negative regulation of catalytic activity|positive regulation of transcription from RNA polymerase II promoter|regulation of nucleocytoplasmic transport|centrosome organization|,phosphoprotein phosphatase activity|enzyme inhibitor activity|protein binding|phosphatase regulator activity|protein kinase binding|14-3-3 protein binding|,9,1.5,68.7,10,0.8,39.8,1.3,104,104,1.00E-05,1,1,0.9,1.8
ENSMUSG00000020346,MGAT1,mannoside acetylglucosaminyltransferase 1,Golgi apparatus|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,in utero embryonic development|UDP-N-acetylglucosamine catabolic process|protein glycosylation|,"alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",9,0.9,25.4,9,1.1,69.2,1,93.7,93.7,2.00E-05,1,1,0.7,1.4
ENSMUSG00000079316,RAB9,"RAB9, member RAS oncogene family",lysosome|endosome|late endosome|plasma membrane|membrane|cytoplasmic vesicle|phagocytic vesicle|extracellular vesicular exosome|,GTP catabolic process|transport|small GTPase mediated signal transduction|protein transport|positive regulation of exocytosis|,nucleotide binding|GTPase activity|GTP binding|GDP binding|,10,0.9,18,10,1.1,64.4,1,81.2,81.2,4.00E-05,1,1,0.8,1.6
ENSMUSG00000024858,ADRBK1,"adrenergic receptor kinase, beta 1",cytoplasm|caveola|membrane|membrane|basolateral plasma membrane|apical plasma membrane|axon|dendritic spine|dendritic shaft|synapse|,regulation of the force of heart contraction|desensitization of G-protein coupled receptor protein signaling pathway|desensitization of G-protein coupled receptor protein signaling pathway|desensitization of G-protein coupled receptor protein signaling pathway|negative regulation of the force of heart contraction by chemical signal|protein phosphorylation|protein phosphorylation|protein phosphorylation|response to oxidative stress|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|tachykinin receptor signaling pathway|heart development|response to organic cyclic compound|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|receptor internalization|positive regulation of catecholamine secretion|termination of G-protein coupled receptor signaling pathway|follicle-stimulating hormone signaling pathway|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of striated muscle contraction|cardiac muscle contraction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|G-protein coupled receptor kinase activity|G-protein coupled receptor kinase activity|G-protein coupled receptor kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Edg-2 lysophosphatidic acid receptor binding|beta-adrenergic receptor kinase activity|",10,0.7,15,10,1.7,68.4,1.3,77.6,77.6,6.00E-05,1,1,1.1,2.1
ENSMUSG00000032788,PDXK,"pyridoxal (pyridoxine, vitamin B6) kinase",nucleus|cytoplasm|cytosol|extracellular vesicular exosome|,cell proliferation|pyridoxal 5'-phosphate salvage|phosphorylation|pyridoxal phosphate biosynthetic process|negative regulation of apoptotic process|,nucleotide binding|magnesium ion binding|ATP binding|drug binding|zinc ion binding|pyridoxal kinase activity|kinase activity|transferase activity|pyridoxal phosphate binding|potassium ion binding|sodium ion binding|lithium ion binding|protein homodimerization activity|metal ion binding|pyridoxal binding|,9,1.4,45.9,9,0.9,35.2,1.3,77.5,77.5,6.00E-05,1,1,0.9,1.8
ENSMUSG00000079426,ARPC4,"actin related protein 2/3 complex, subunit 4",cytoplasm|cytoskeleton|Arp2/3 protein complex|Arp2/3 protein complex|cell projection|extracellular vesicular exosome|,biological_process|actin filament polymerization|Arp2/3 complex-mediated actin nucleation|,"actin binding|enzyme binding|protein binding, bridging|",8,0.5,9.69,8,1.5,58.8,1.2,66.5,66.5,0.00039,1,1,0.8,2
ENSMUSG00000033554,DPH5,DPH5 homolog (S. cerevisiae),cellular_component|,biological_process|metabolic process|peptidyl-diphthamide biosynthetic process from peptidyl-histidine|methylation|,molecular_function|diphthine synthase activity|methyltransferase activity|transferase activity|,10,0.6,4.97,10,1,58,1,60.8,60.8,0.00065,1,1,0.7,1.6
ENSMUSG00000040236,TRAPPC5,trafficking protein particle complex 5,endoplasmic reticulum|Golgi apparatus|TRAPP complex|,transport|biological_process|vesicle-mediated transport|,protein binding|,8,0.3,1.02,8,1.1,54.2,1,52.8,52.8,0.00175,0,0,0.7,1.8
ENSMUSG00000025260,HSD17B10,hydroxysteroid (17-beta) dehydrogenase 10,mitochondrion|mitochondrion|mitochondrial inner membrane|endoplasmic reticulum|,tRNA processing|metabolic process|protein homotetramerization|oxidation-reduction process|,beta-amyloid binding|3-hydroxyacyl-CoA dehydrogenase activity|estradiol 17-beta-dehydrogenase activity|steroid binding|oxidoreductase activity|acetoacetyl-CoA reductase activity|testosterone dehydrogenase [NAD(P)] activity|estrogen receptor binding|identical protein binding|poly(A) RNA binding|3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity|NAD binding|,4,0.9,9.51,6,1.6,42.7,1.5,50.3,50.3,0.00263,0,0,0.9,2.5
ENSMUSG00000032312,CSK,c-src tyrosine kinase,intracellular|cytoplasm|plasma membrane|plasma membrane|cell-cell junction|membrane|membrane raft|extracellular vesicular exosome|,immune system process|protein phosphorylation|protein phosphorylation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of low-density lipoprotein particle clearance|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|negative regulation of interleukin-6 production|negative regulation of kinase activity|intracellular signal transduction|negative regulation of Golgi to plasma membrane protein transport|positive regulation of MAP kinase activity|negative regulation of bone resorption|protein autophosphorylation|negative regulation of phagocytosis|regulation of T cell activation|regulation of Fc receptor mediated stimulatory signaling pathway|negative regulation of ERK1 and ERK2 cascade|cellular response to peptide hormone stimulus|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|identical protein binding|proline-rich region binding|",9,1,24,7,1.4,26.9,1.1,49.6,49.6,0.00299,0,0,0.8,1.8
ENSMUSG00000025240,SACM1L,"SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae)",endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,phosphatidylinositol dephosphorylation|,"phosphatidylinositol-3-phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|phosphatidylinositol bisphosphate phosphatase activity|phosphoric ester hydrolase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,1.3,36.4,10,0.7,15.7,0.9,49.3,49.3,0.00317,0,0,0.7,1.7
ENSMUSG00000010066,CACNA2D2,"calcium channel, voltage-dependent, alpha 2/delta subunit 2",voltage-gated calcium channel complex|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|calcium ion transport|neuromuscular junction development|regulation of ion transmembrane transport|regulation of multicellular organism growth|positive regulation of organ growth|muscle fiber development|rhythmic synaptic transmission|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|metal ion binding|,10,-1.2,4.4,10,1,50.5,0.9,48.8,48.8,0.0036,0,0,0.5,1.6
ENSMUSG00000019804,SNX3,sorting nexin 3,cytoplasm|endosome|early endosome|endosome membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,heme biosynthetic process|transport|protein transport|regulation of cellular protein metabolic process|regulation of intracellular protein transport|transferrin transport|hemoglobin biosynthetic process|,protein binding|lipid binding|protein phosphatase binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol binding|,10,0.8,11.6,10,1,34.5,0.9,45.4,45.4,0.00598,0,0,0.5,1.3
ENSMUSG00000038563,EFTUD1,elongation factor Tu GTP binding domain containing 1,cellular_component|,GTP catabolic process|translation|translational elongation|ribosome biogenesis|mature ribosome assembly|,nucleotide binding|translation elongation factor activity|GTPase activity|GTP binding|ribosome binding|,9,1.1,8.47,10,0.9,36.1,1.1,44.1,44.1,0.00695,0,0,0.6,1.6
ENSMUSG00000026288,INPP5D,inositol polyphosphate-5-phosphatase D,intracellular|cytoplasm|cytosol|actin filament|plasma membrane|membrane|cortical cytoskeleton|,immune system process|apoptotic process|negative regulation of cell proliferation|determination of adult lifespan|negative regulation of signal transduction|immunoglobulin mediated immune response|dephosphorylation|negative regulation of granulocyte differentiation|negative regulation of B cell proliferation|intracellular signal transduction|positive regulation of apoptotic process|negative regulation of interleukin-6 biosynthetic process|positive regulation of B cell differentiation|positive regulation of lymphocyte differentiation|positive regulation of erythrocyte differentiation|negative regulation of monocyte differentiation|negative regulation of neutrophil differentiation|negative regulation of osteoclast differentiation|negative regulation of bone resorption|phosphatidylinositol dephosphorylation|negative regulation of immune response|negative regulation of B cell activation|,"inositol-polyphosphate 5-phosphatase activity|protein binding|hydrolase activity|SH3 domain binding|inositol-4,5-bisphosphate 5-phosphatase activity|phosphatidylinositol trisphosphate phosphatase activity|PTB domain binding|",10,-0.8,15.2,10,-0.7,28.4,-0.7,43.1,-43.1,0.00737,0,0,-1.2,-0.5
ENSMUSG00000003808,FARSA,"phenylalanyl-tRNA synthetase, alpha subunit",cytoplasm|membrane|,translation|tRNA aminoacylation for protein translation|phenylalanyl-tRNA aminoacylation|biological_process|tRNA aminoacylation|,tRNA binding|nucleotide binding|aminoacyl-tRNA ligase activity|phenylalanine-tRNA ligase activity|ATP binding|ligase activity|poly(A) RNA binding|,7,1.6,18.1,6,1.1,25.3,1.5,42.2,42.2,0.00768,0,0,0.9,2.9
ENSMUSG00000042046,DSTYK,dual serine/threonine and tyrosine protein kinase,cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.8,25.9,10,-0.5,19.3,-0.7,42.1,-42.1,0.00775,0,0,-0.9,-0.4
ENSMUSG00000032199,POLR2M,polymerase (RNA) II (DNA directed) polypeptide M,"nucleus|nuclear envelope|DNA-directed RNA polymerase II, holoenzyme|neuronal cell body|","transcription, DNA-templated|maintenance of ER location|",molecular_function|DNA-directed RNA polymerase activity|,10,2,26,9,1,18.1,1.9,41.3,41.3,0.00803,0,0,0.7,3.4
ENSMUSG00000071074,YIPF3,"Yip1 domain family, member 3",cytoplasm|Golgi apparatus|plasma membrane|membrane|integral component of membrane|transport vesicle|intracellular membrane-bounded organelle|,biological_process|cell differentiation|,molecular_function|,10,1.6,12.7,10,1.1,29.9,1.3,41.2,41.2,0.00811,0,0,0.7,2.5
ENSMUSG00000036450,HIF1AN,"hypoxia-inducible factor 1, alpha subunit inhibitor",nucleus|nucleus|cytoplasm|perinuclear region of cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|peptidyl-histidine hydroxylation|peptidyl-aspartic acid hydroxylation|peptidyl-asparagine hydroxylation|positive regulation of myoblast differentiation|negative regulation of Notch signaling pathway|oxidation-reduction process|negative regulation of transcription from RNA polymerase II promoter in response to hypoxia|","Notch binding|iron ion binding|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|carboxylic acid binding|peptidyl-histidine dioxygenase activity|peptidyl-asparagine 3-dioxygenase activity|protein homodimerization activity|metal ion binding|cofactor binding|NF-kappaB binding|dioxygenase activity|ankyrin repeat binding|",10,-0.7,14.6,10,-0.6,27,-0.6,41.1,-41.1,0.00816,0,0,-1,-0.5
ENSMUSG00000024621,CSF1R,colony stimulating factor 1 receptor,intracellular|plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|,positive regulation of protein phosphorylation|immune system process|protein phosphorylation|inflammatory response|transmembrane receptor protein tyrosine kinase signaling pathway|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of cell shape|regulation of cell shape|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cytokine-mediated signaling pathway|hemopoiesis|osteoclast differentiation|positive regulation of cell migration|ruffle organization|cellular response to macrophage colony-stimulating factor stimulus|cellular response to macrophage colony-stimulating factor stimulus|macrophage colony-stimulating factor signaling pathway|macrophage colony-stimulating factor signaling pathway|positive regulation of tyrosine phosphorylation of Stat3 protein|innate immune response|regulation of bone resorption|cell-cell junction maintenance|positive regulation of osteoclast differentiation|phosphatidylinositol metabolic process|protein autophosphorylation|protein autophosphorylation|phosphatidylinositol-mediated signaling|positive regulation of protein tyrosine kinase activity|positive regulation of ERK1 and ERK2 cascade|cellular response to cytokine stimulus|positive regulation of protein serine/threonine kinase activity|positive regulation of chemokine secretion|positive regulation of cell motility|regulation of actin cytoskeleton reorganization|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|macrophage colony-stimulating factor receptor activity|macrophage colony-stimulating factor receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|cytokine binding|cytokine binding|cytokine binding|protein homodimerization activity|",8,1.1,5.03,9,-1.4,40.1,-1.4,40.2,-40.2,0.00866,0,0,-2.7,-1
ENSMUSG00000029213,COMMD8,COMM domain containing 8,cellular_component|,biological_process|,molecular_function|,9,0.9,11.5,9,1,27.4,0.9,38.5,38.5,0.00978,0,0,0.5,1.5
ENSMUSG00000018559,CTDNEP1,CTD nuclear envelope phosphatase 1,nucleus|nuclear envelope|cytoplasm|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|nuclear membrane|Nem1-Spo7 phosphatase complex|,protein dephosphorylation|nuclear envelope organization|gamete generation|gamete generation|mesoderm development|positive regulation of triglyceride biosynthetic process|protein localization to nucleus|positive regulation of canonical Wnt signaling pathway|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,10,0.4,1.19,10,0.9,38.8,0.9,38.1,38.1,0.01,0,0,0.5,1.5
ENSMUSG00000019082,SLC25A22,"solute carrier family 25 (mitochondrial carrier, glutamate), member 22",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|L-glutamate transport|transmembrane transport|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|symporter activity|,9,0.6,2.16,9,0.9,36.8,0.8,38,38,0.0101,0,0,0.5,1.6
ENSMUSG00000026356,DARS,aspartyl-tRNA synthetase,cytoplasm|membrane|extracellular vesicular exosome|,translation|tRNA aminoacylation for protein translation|aspartyl-tRNA aminoacylation|,nucleotide binding|nucleic acid binding|aminoacyl-tRNA ligase activity|aspartate-tRNA ligase activity|ATP binding|ligase activity|poly(A) RNA binding|,9,1,3.7,8,1.5,34.8,1.2,37.4,37.4,0.0105,0,0,0.8,2.3
ENSMUSG00000073838,TUFM,"Tu translation elongation factor, mitochondrial",intracellular|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|mitochondrial nucleoid|extracellular vesicular exosome|,translation|translational elongation|,nucleotide binding|translation elongation factor activity|GTPase activity|GTP binding|poly(A) RNA binding|,7,-0.7,5.92,7,-1.8,35.7,-1.8,37.3,-37.3,0.0106,0,0,-3.3,-1.1
ENSMUSG00000006304,ARPC2,"actin related protein 2/3 complex, subunit 2",cytoplasm|endosome|Golgi apparatus|cytoskeleton|Arp2/3 protein complex|plasma membrane|focal adhesion|cell junction|cell leading edge|cell projection|neuron projection|synapse|extracellular vesicular exosome|,positive regulation of lamellipodium assembly|regulation of actin filament polymerization|positive regulation of actin filament polymerization|positive regulation of substrate adhesion-dependent cell spreading|,actin binding|protein binding|,10,0.7,7.44,10,0.8,29.5,0.8,36.3,36.3,0.0113,0,0,0.4,1.1
ENSMUSG00000025781,ATP5C1,"ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1","mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|membrane|proton-transporting ATP synthase complex, catalytic core F(1)|extracellular vesicular exosome|",ADP biosynthetic process|ATP catabolic process|ATP biosynthetic process|transport|ion transport|ATP synthesis coupled proton transport|proton transport|ATP metabolic process|,"ATPase activity|ATPase activity|poly(A) RNA binding|proton-transporting ATP synthase activity, rotational mechanism|proton-transporting ATPase activity, rotational mechanism|",7,-0.8,5.88,7,-1.4,32.5,-1.2,36,-36,0.0116,0,0,-2.3,-0.7
ENSMUSG00000042228,LYN,Yamaguchi sarcoma viral (v-yes-1) oncogene homolog,cell|nucleus|nucleus|cytoplasm|mitochondrial intermembrane space|Golgi apparatus|plasma membrane|plasma membrane|cell-cell adherens junction|postsynaptic density|membrane|mitochondrial crista|mitochondrial membrane|integrin alpha2-beta1 complex|mast cell granule|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,B cell homeostasis|regulation of cytokine production|negative regulation of protein phosphorylation|immune system process|Fc receptor mediated stimulatory signaling pathway|tolerance induction to self antigen|histamine secretion by mast cell|platelet degranulation|negative regulation of myeloid leukocyte differentiation|immune response-regulating cell surface receptor signaling pathway|Fc receptor mediated inhibitory signaling pathway|regulation of B cell apoptotic process|protein phosphorylation|inflammatory response|cellular response to DNA damage stimulus|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|response to hormone|positive regulation of neuron projection development|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|hemopoiesis|erythrocyte differentiation|positive regulation of cell migration|negative regulation of B cell proliferation|neuron projection development|lipopolysaccharide-mediated signaling pathway|regulation of mast cell activation|regulation of cell adhesion mediated by integrin|negative regulation of toll-like receptor 2 signaling pathway|negative regulation of toll-like receptor 4 signaling pathway|intracellular signal transduction|positive regulation of phosphorylation|positive regulation of tyrosine phosphorylation of STAT protein|hemoglobin biosynthetic process|regulation of mast cell degranulation|negative regulation of MAP kinase activity|positive regulation of phosphatidylinositol 3-kinase activity|innate immune response|regulation of erythrocyte differentiation|protein autophosphorylation|protein autophosphorylation|protein autophosphorylation|cytokine secretion|regulation of cytokine secretion|regulation of inflammatory response|positive regulation of peptidyl-tyrosine phosphorylation|B cell receptor signaling pathway|regulation of B cell receptor signaling pathway|positive regulation of B cell receptor signaling pathway|positive regulation of cellular component movement|regulation of release of sequestered calcium ion into cytosol|regulation of release of sequestered calcium ion into cytosol|positive regulation of glial cell proliferation|positive regulation of Fc receptor mediated stimulatory signaling pathway|positive regulation of stress-activated protein kinase signaling cascade|regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 and ERK2 cascade|positive regulation of oligodendrocyte progenitor proliferation|negative regulation of mast cell proliferation|positive regulation of mast cell proliferation|cellular response to retinoic acid|regulation of monocyte chemotaxis|regulation of platelet aggregation|dendritic cell differentiation|negative regulation of intracellular signal transduction|positive regulation of dendritic cell apoptotic process|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|receptor binding|erythropoietin receptor binding|platelet-derived growth factor receptor binding|integrin binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SH3 domain binding|enzyme binding|ubiquitin protein ligase binding|protein complex binding|protein complex binding|gamma-tubulin binding|glycosphingolipid binding|ion channel binding|phosphoprotein binding|",10,1.3,35.2,10,0.2,1.61,1,33.7,33.7,0.014,0,0,0.6,2.1
ENSMUSG00000026103,GLS,glutaminase,cytoplasm|mitochondrion|,suckling behavior|regulation of respiratory gaseous exchange by neurological system process|glutamate biosynthetic process|glutamate biosynthetic process|glutamine metabolic process|glutamine catabolic process|glutamine catabolic process|glutamine catabolic process|synaptic transmission|protein homotetramerization|protein homotetramerization|,glutaminase activity|glutaminase activity|glutaminase activity|protein binding|hydrolase activity|,10,0.6,6.81,10,1.4,29.5,1,32.9,32.9,0.0151,0,0,0.6,1.9
ENSMUSG00000020089,PPA1,pyrophosphatase (inorganic) 1,cytoplasm|extracellular vesicular exosome|,phosphate-containing compound metabolic process|,magnesium ion binding|inorganic diphosphatase activity|pyrophosphatase activity|hydrolase activity|metal ion binding|,6,1.6,29.9,6,0.6,6.67,1.4,32.9,32.9,0.0151,0,0,0.7,2.6
ENSMUSG00000021468,SPTLC1,"serine palmitoyltransferase, long chain base subunit 1",endoplasmic reticulum|membrane|integral component of membrane|serine C-palmitoyltransferase complex|serine C-palmitoyltransferase complex|SPOTS complex|,lipid metabolic process|sphingolipid metabolic process|sphingomyelin biosynthetic process|sphingomyelin biosynthetic process|biosynthetic process|sphinganine biosynthetic process|sphingosine biosynthetic process|ceramide biosynthetic process|,"catalytic activity|protein binding|transferase activity|transferase activity, transferring acyl groups|pyridoxal phosphate binding|",8,1.6,25.5,8,0.7,10.1,0.9,32.4,32.4,0.0159,0,0,0.6,2.4
ENSMUSG00000022450,NDUFA6,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)",mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|mitochondrial membrane|respiratory chain|,transport|response to oxidative stress|oxidation-reduction process|,molecular_function|,10,1.1,4.72,10,-1.8,35.1,-1.8,31.7,-31.7,0.0169,0,0,-2.9,-1.2
ENSMUSG00000045482,TRRAP,transformation/transcription domain-associated protein,histone acetyltransferase complex|Swr1 complex|nucleus|transcription factor complex|STAGA complex|transcription factor TFTC complex|NuA4 histone acetyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mitotic cell cycle checkpoint|chromatin modification|histone deubiquitination|histone H4 acetylation|histone H2A acetylation|regulation of RNA biosynthetic process|","transcription cofactor activity|transcription coactivator activity|protein binding|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|",10,0.8,7.32,10,0.8,24.5,0.8,31.4,31.4,0.0175,0,0,0.4,1.4
ENSMUSG00000031278,ACSL4,acyl-CoA synthetase long-chain family member 4,cytoplasm|mitochondrion|mitochondrial outer membrane|peroxisome|endoplasmic reticulum|lipid particle|membrane|membrane|integral component of membrane|mitochondrial membrane|neuronal cell body|intracellular membrane-bounded organelle|ER-mitochondrion membrane contact site|extracellular vesicular exosome|,long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|triglyceride metabolic process|metabolic process|lipid biosynthetic process|fatty acid transport|regulation of fatty acid metabolic process|neuron differentiation|positive regulation of cell growth|negative regulation of prostaglandin secretion|embryonic process involved in female pregnancy|dendritic spine development|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|ATP binding|ligase activity|very long-chain fatty acid-CoA ligase activity|arachidonate-CoA ligase activity|,9,2.1,29.9,8,0.6,6.51,2,30.8,30.8,0.0186,0,0,0.8,3.2
ENSMUSG00000029283,CDC7,cell division cycle 7 (S. cerevisiae),nucleus|cytoplasm|microtubule cytoskeleton|intercellular bridge|,protein phosphorylation|cell cycle|positive regulation of cell proliferation|positive regulation of nuclear cell cycle DNA replication|positive regulation of G2/M transition of mitotic cell cycle|phosphorylation|cell cycle phase transition|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-1.2,20.3,10,-1,10.8,-1,30.6,-30.6,0.019,0,0,-1.6,-0.6
ENSMUSG00000040472,RABGGTA,"Rab geranylgeranyl transferase, a subunit",Rab-protein geranylgeranyltransferase complex|,protein prenylation|protein geranylgeranylation|protein geranylgeranylation|,prenyltransferase activity|Rab geranylgeranyltransferase activity|Rab geranylgeranyltransferase activity|zinc ion binding|protein prenyltransferase activity|transferase activity|Rab GTPase binding|,6,-0.7,8.79,6,-1.4,25.1,-1.4,30.6,-30.6,0.019,0,0,-2.5,-0.7
ENSMUSG00000026395,PTPRC,"protein tyrosine phosphatase, receptor type, C",intracellular|plasma membrane|integral component of plasma membrane|focal adhesion|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|extracellular vesicular exosome|cell periphery|,activation of MAPK activity|negative regulation of T cell mediated cytotoxicity|positive regulation of T cell mediated cytotoxicity|negative regulation of cytokine-mediated signaling pathway|hematopoietic progenitor cell differentiation|immunoglobulin biosynthetic process|positive regulation of T cell mediated immunity|regulation of humoral immune response mediated by circulating immunoglobulin|positive regulation of humoral immune response mediated by circulating immunoglobulin|negative regulation of protein kinase activity|negative regulation of protein kinase activity|protein dephosphorylation|negative regulation of cell adhesion involved in substrate-bound cell migration|leukocyte cell-cell adhesion|response to gamma radiation|dephosphorylation|B cell differentiation|T cell differentiation|positive regulation of B cell proliferation|positive regulation of B cell proliferation|negative regulation of protein autophosphorylation|heterotypic cell-cell adhesion|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|T cell proliferation|B cell proliferation|positive regulation of T cell proliferation|positive regulation of MAPK cascade|cell cycle phase transition|positive thymic T cell selection|negative thymic T cell selection|regulation of B cell differentiation|positive regulation of T cell differentiation|positive regulation of gamma-delta T cell differentiation|positive regulation of alpha-beta T cell proliferation|positive regulation of isotype switching to IgG isotypes|bone marrow development|stem cell development|negative regulation of peptidyl-tyrosine phosphorylation|T cell receptor signaling pathway|B cell receptor signaling pathway|regulation of B cell receptor signaling pathway|positive regulation of antigen receptor-mediated signaling pathway|release of sequestered calcium ion into cytosol|defense response to virus|defense response to virus|regulation of cell cycle|positive regulation of hematopoietic stem cell migration|positive regulation of stem cell proliferation|regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|protein binding|heparin binding|hydrolase activity|phosphatase activity|protein kinase binding|protein kinase binding|heparan sulfate proteoglycan binding|,10,1.6,20.2,10,0.5,13.2,0.9,29.9,29.9,0.0205,0,0,0.3,2.2
ENSMUSG00000024576,CSNK1A1,"casein kinase 1, alpha 1","chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|centrosome|mRNA cleavage and polyadenylation specificity factor complex|cytoskeleton|membrane|nuclear speck|ribonucleoprotein complex|",cell morphogenesis|protein phosphorylation|protein phosphorylation|cell cycle|mitotic nuclear division|Wnt signaling pathway|phosphorylation|cell division|,"nucleotide binding|magnesium ion binding|glycoprotein binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|peptide binding|phosphoprotein binding|",6,-0.6,4.54,6,1.1,26.1,1.1,29.8,29.8,0.0207,0,0,0.7,2
ENSMUSG00000026895,NDUFA8,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial intermembrane space|respiratory chain|,transport|biological_process|oxidation-reduction process|,protein complex binding|,8,-0.6,3.75,7,0.9,28.9,0.6,29.8,29.8,0.0207,0,0,0.4,1.5
ENSMUSG00000031314,TAF1,"TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|pronucleus|MLL1 complex|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|cell cycle|phosphorylation|histone acetylation|histone acetylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|","nucleotide binding|p53 binding|DNA binding|transcription coactivator activity|histone acetyltransferase activity|histone acetyltransferase activity|protein serine/threonine kinase activity|protein binding|ATP binding|transcription factor binding|kinase activity|transferase activity|transferase activity, transferring acyl groups|TBP-class protein binding|lysine-acetylated histone binding|",10,-1.2,16.8,9,-0.9,13.7,-1.1,29,-29,0.0227,0,0,-1.8,-0.7
ENSMUSG00000022781,PAK2,p21 protein (Cdc42/Rac)-activated kinase 2,nucleus|cytoplasm|membrane|,protein phosphorylation|protein phosphorylation|apoptotic process|metabolic process|phosphorylation|peptidyl-serine phosphorylation|signal transduction by phosphorylation|regulation of growth|negative regulation of apoptotic process|protein autophosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of protein tyrosine kinase activity|positive regulation of extrinsic apoptotic signaling pathway|negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis|,"nucleotide binding|catalytic activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein tyrosine kinase activator activity|identical protein binding|",10,2.2,30.3,10,0.4,5.03,2.1,28.9,28.9,0.023,0,0,0.9,3.3
ENSMUSG00000019916,P4HA1,"procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide",mitochondrion|endoplasmic reticulum|membrane|procollagen-proline 4-dioxygenase complex|intracellular membrane-bounded organelle|,peptidyl-proline hydroxylation to 4-hydroxy-L-proline|peptidyl-proline hydroxylation|collagen fibril organization|oxidation-reduction process|,"procollagen-proline 4-dioxygenase activity|procollagen-proline 4-dioxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|L-ascorbic acid binding|metal ion binding|dioxygenase activity|",9,0.8,8.74,8,0.9,20.1,0.8,28.4,28.4,0.0246,0,0,0.5,1.5
ENSMUSG00000038861,PI4KB,"phosphatidylinositol 4-kinase, catalytic, beta polypeptide",cytoplasm|cytoplasm|mitochondrion|mitochondrial outer membrane|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|membrane|,phosphatidylinositol biosynthetic process|phosphorylation|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|,"nucleotide binding|1-phosphatidylinositol 4-kinase activity|1-phosphatidylinositol 4-kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|",9,1.4,29,8,-1.1,2.74,1.3,28.2,28.2,0.0254,0,0,0.7,2.5
ENSMUSG00000021598,MED10,mediator complex subunit 10,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|stem cell maintenance|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|molecular_function|,6,-1.4,30.2,7,-0.2,0.823,-1.4,27.8,-27.8,0.0267,0,0,-2.7,-0.6
ENSMUSG00000018995,NARS2,asparaginyl-tRNA synthetase 2 (mitochondrial)(putative),cytoplasm|mitochondrion|,translation|tRNA aminoacylation for protein translation|asparaginyl-tRNA aminoacylation|,nucleotide binding|nucleic acid binding|aminoacyl-tRNA ligase activity|asparagine-tRNA ligase activity|ATP binding|ligase activity|,8,-1.2,27.9,5,-0.3,2.91,-1.2,27.5,-27.5,0.0279,0,0,-1.9,-0.8
ENSMUSG00000050217,LGSN,"lengsin, lens protein with glutamine synthetase domain",plasma membrane|,glutamine biosynthetic process|nitrogen compound metabolic process|,catalytic activity|glutamate-ammonia ligase activity|protein binding|,10,1.3,4,10,1.3,23.8,1.3,27.4,27.4,0.0283,0,0,0.9,2
ENSMUSG00000003814,CALR,calreticulin,acrosomal vesicle|extracellular space|extracellular space|nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|smooth endoplasmic reticulum|Golgi apparatus|cytosol|polysome|external side of plasma membrane|cell surface|membrane|sarcoplasmic reticulum|extracellular matrix|MHC class I peptide loading complex|intracellular membrane-bounded organelle|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|peptide antigen assembly with MHC class I protein complex|protein folding|protein export from nucleus|cell cycle arrest|positive regulation of cell proliferation|positive regulation of gene expression|negative regulation of translation|cortical actin cytoskeleton organization|negative regulation of intracellular steroid hormone receptor signaling pathway|protein localization to nucleus|protein localization to nucleus|regulation of meiosis|negative regulation of neuron differentiation|positive regulation of DNA replication|positive regulation of cell cycle|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|negative regulation of retinoic acid receptor signaling pathway|positive regulation of phagocytosis|protein stabilization|chaperone-mediated protein folding|cellular senescence|cellular senescence|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of dendritic cell chemotaxis|",glycoprotein binding|mRNA binding|mRNA binding|integrin binding|iron ion binding|calcium ion binding|calcium ion binding|protein binding|carbohydrate binding|ubiquitin protein ligase binding|peptide binding|hormone binding|poly(A) RNA binding|metal ion binding|androgen receptor binding|unfolded protein binding|,10,0.7,13.1,10,0.6,14.8,0.6,27.3,27.3,0.0287,0,0,0.4,1
ENSMUSG00000031065,CDK16,cyclin-dependent kinase 16,cell|cytoplasm|plasma membrane|synaptic vesicle|synaptic vesicle|microtubule cytoskeleton|cell junction|extrinsic component of cytoplasmic side of plasma membrane|cytoplasmic vesicle|neuron projection|synapse|,protein phosphorylation|exocytosis|spermatogenesis|phosphorylation|cell differentiation|growth hormone secretion|neuron projection development|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of insulin secretion involved in cellular response to glucose stimulus|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.2,1.89,10,1.3,25.1,1.3,26.6,26.6,0.0318,0,0,0.9,2
ENSMUSG00000028969,CDK5,cyclin-dependent kinase 5,intracellular|cell|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytoskeleton|plasma membrane|postsynaptic density|membrane|cyclin-dependent protein kinase 5 holoenzyme complex|lamellipodium|cell junction|filopodium|axon|axon|dendrite|growth cone|neuromuscular junction|cell projection|neuronal cell body|synapse|postsynaptic membrane|,"neuron migration|synaptic transmission, dopaminergic|protein phosphorylation|protein phosphorylation|protein phosphorylation|protein phosphorylation|intracellular protein transport|exocytosis|nucleocytoplasmic transport|apoptotic process|cell cycle|cell-matrix adhesion|nervous system development|axonogenesis|synapse assembly|skeletal muscle tissue development|motor neuron axon guidance|cell death|associative learning|visual learning|response to wounding|Schwann cell development|phosphorylation|cell migration|cell migration|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|sensory perception of pain|telencephalon development|cerebellum development|cerebellar cortex development|cerebellar cortex formation|hippocampus development|layer formation in cerebral cortex|central nervous system neuron development|cerebral cortex development|corpus callosum development|neuron differentiation|neuron differentiation|neuron differentiation|regulation of cell migration|negative regulation of axon extension|cortical actin cytoskeleton organization|forebrain development|neuron projection development|negative regulation of protein ubiquitination|negative regulation of synaptic plasticity|positive regulation of protein binding|receptor catabolic process|serine phosphorylation of STAT3 protein|synaptic transmission, glutamatergic|protein localization to synapse|response to cocaine|receptor clustering|positive regulation of neuron apoptotic process|regulated secretory pathway|negative regulation of cell cycle|positive regulation of protein kinase activity|negative regulation of proteolysis|negative regulation of transcription, DNA-templated|positive regulation of calcium ion-dependent exocytosis|protein autophosphorylation|negative regulation of protein export from nucleus|behavioral response to cocaine|regulation of synaptic plasticity|synaptic vesicle endocytosis|rhythmic process|oligodendrocyte differentiation|neuron projection morphogenesis|dendrite morphogenesis|cell division|neuron apoptotic process|neuron apoptotic process|regulation of cell cycle|regulation of postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|regulation of dendritic spine morphogenesis|calcium ion import|positive regulation of protein targeting to membrane|negative regulation of neuron death|positive regulation of receptor activity|","nucleotide binding|p53 binding|protein kinase activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ErbB-2 class receptor binding|protein binding|ATP binding|cytoskeletal protein binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|acetylcholine receptor activator activity|ErbB-3 class receptor binding|ephrin receptor binding|tau-protein kinase activity|",10,-1,6.54,10,-1.7,22.6,-1.7,26.5,-26.5,0.0322,0,0,-2.9,-1.1
ENSMUSG00000034187,NSF,N-ethylmaleimide sensitive fusion protein,cytoplasm|lysosomal membrane|Golgi stack|plasma membrane|postsynaptic density|dendritic shaft|extracellular vesicular exosome|,positive regulation of receptor recycling|ATP catabolic process|ATP catabolic process|transport|potassium ion transport|protein transport|vesicle-mediated transport|regulation of exocytosis|,"nucleotide binding|protein binding|ATP binding|protein C-terminus binding|hydrolase activity|ATPase activity|Rab GTPase binding|syntaxin binding|PDZ domain binding|D1 dopamine receptor binding|protein complex binding|ATPase activity, coupled|ATP-dependent protein binding|metal ion binding|",8,-0.6,4.07,9,0.7,27,0.6,26.4,26.4,0.0327,0,0,0.3,1.5
ENSMUSG00000031987,EGLN1,egl-9 family hypoxia-inducible factor 1,nucleus|cytoplasm|cytosol|,response to hypoxia|peptidyl-proline hydroxylation to 4-hydroxy-L-proline|negative regulation of cAMP catabolic process|oxygen homeostasis|negative regulation of sequence-specific DNA binding transcription factor activity|regulation of angiogenesis|negative regulation of cyclic-nucleotide phosphodiesterase activity|cardiac muscle tissue morphogenesis|oxidation-reduction process|heart trabecula formation|ventricular septum morphogenesis|labyrinthine layer development|response to nitric oxide|,"iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|enzyme binding|L-ascorbic acid binding|peptidyl-proline dioxygenase activity|peptidyl-proline 4-dioxygenase activity|metal ion binding|dioxygenase activity|",8,0.6,3.18,8,1.2,24.9,0.8,26.2,26.2,0.0336,0,0,0.5,1.9
ENSMUSG00000037580,GCH1,GTP cyclohydrolase 1,nucleus|cytoplasm|cytosol|cytoplasmic vesicle|nuclear membrane|protein complex|,GTP catabolic process|protein complex assembly|tetrahydrobiopterin biosynthetic process|tetrahydrobiopterin biosynthetic process|metabolic process|regulation of blood pressure|regulation of blood pressure|regulation of lung blood pressure|response to interferon-gamma|response to tumor necrosis factor|vasodilation|dopamine biosynthetic process|pteridine-containing compound biosynthetic process|negative regulation of blood pressure|tetrahydrofolate biosynthetic process|response to pain|neuromuscular process controlling posture|positive regulation of nitric-oxide synthase activity|dihydrobiopterin metabolic process|protein homooligomerization|protein heterooligomerization|,nucleotide binding|catalytic activity|GTP cyclohydrolase I activity|GTP cyclohydrolase I activity|calcium ion binding|GTP binding|zinc ion binding|hydrolase activity|GTP-dependent protein binding|protein homodimerization activity|metal ion binding|coenzyme binding|,10,0.7,5.68,10,0.7,20.8,0.7,26.1,26.1,0.0342,0,0,0.4,1.2
ENSMUSG00000028107,TARS2,"threonyl-tRNA synthetase 2, mitochondrial (putative)",cytoplasm|mitochondrion|,translation|tRNA aminoacylation for protein translation|threonyl-tRNA aminoacylation|tRNA aminoacylation|,"nucleotide binding|aminoacyl-tRNA ligase activity|threonine-tRNA ligase activity|ATP binding|ligase activity|ligase activity, forming aminoacyl-tRNA and related compounds|",6,0.6,10.6,5,1,16.7,0.7,25.8,25.8,0.0357,0,0,0.4,1.5
ENSMUSG00000026864,HSPA5,heat shock protein 5,nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum membrane|smooth endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|endoplasmic reticulum-Golgi intermediate compartment|plasma membrane|COP9 signalosome|cell surface|membrane|integral component of endoplasmic reticulum membrane|midbody|endoplasmic reticulum chaperone complex|extracellular vesicular exosome|,ER overload response|activation of signaling protein activity involved in unfolded protein response|cerebellum structural organization|cerebellar Purkinje cell layer development|positive regulation of cell migration|negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of protein ubiquitination|response to endoplasmic reticulum stress|maintenance of protein localization in endoplasmic reticulum|positive regulation of embryonic development|cellular response to glucose starvation|negative regulation of apoptotic process|proteolysis involved in cellular protein catabolic process|cellular response to interleukin-4|,nucleotide binding|glycoprotein binding|protein binding|ATP binding|enzyme binding|protein domain specific binding|ubiquitin protein ligase binding|ribosome binding|unfolded protein binding|misfolded protein binding|misfolded protein binding|,6,-1,4.9,6,-0.9,21.2,-0.9,25.6,-25.6,0.037,0,0,-1.8,-0.6
ENSMUSG00000021483,CDK20,cyclin-dependent kinase 20,nucleus|cytoplasm|cilium|cell projection|,protein phosphorylation|cell cycle|multicellular organismal development|phosphorylation|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.642,9,1.3,28.9,1.3,25.6,25.6,0.037,0,0,0.7,2
ENSMUSG00000041417,PIK3R1,"phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)",intracellular|cell|nucleus|cytoplasm|cytosol|plasma membrane|cell-cell junction|phosphatidylinositol 3-kinase complex|phosphatidylinositol 3-kinase complex|membrane|membrane|neuron projection|protein complex|,positive regulation of protein phosphorylation|negative regulation of cell-matrix adhesion|glucose metabolic process|protein phosphorylation|signal transduction|insulin receptor signaling pathway|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of heart rate|positive regulation of gene expression|negative regulation of muscle cell apoptotic process|phosphatidylinositol 3-kinase signaling|phosphorylation|negative regulation of cell-cell adhesion|B cell differentiation|positive regulation of cell migration|positive regulation of cell migration|positive regulation of tumor necrosis factor production|response to insulin|cellular response to UV|cellular response to UV|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol-3-phosphate biosynthetic process|negative regulation of apoptotic process|regulation of phosphatidylinositol 3-kinase activity|positive regulation of myoblast differentiation|negative regulation of osteoclast differentiation|negative regulation of blood pressure|negative regulation of proteolysis|positive regulation of transcription from RNA polymerase II promoter|phosphatidylinositol phosphorylation|insulin-like growth factor receptor signaling pathway|negative regulation of smooth muscle cell proliferation|response to glucocorticoid|NFAT protein import into nucleus|response to cAMP|growth hormone receptor signaling pathway|,receptor binding|insulin receptor binding|insulin-like growth factor receptor binding|platelet-derived growth factor receptor binding|neurotrophin TRKA receptor binding|protein binding|calmodulin binding|protein C-terminus binding|kinase activity|1-phosphatidylinositol-3-kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|protein kinase binding|protein phosphatase binding|protein domain specific binding|estrogen receptor binding|receptor tyrosine kinase binding|ubiquitin protein ligase binding|phosphatidylinositol 3-kinase regulator activity|ErbB-3 class receptor binding|phosphatidylinositol 3-kinase binding|insulin binding|insulin receptor substrate binding|insulin receptor substrate binding|1-phosphatidylinositol-3-kinase regulator activity|ATPase binding|phosphoprotein binding|,10,0.3,0.973,10,0.7,25.9,0.6,25.2,25.2,0.0395,0,0,0.3,1.5
ENSMUSG00000018209,STK4,serine/threonine kinase 4,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|,cell morphogenesis|patterning of blood vessels|neural tube formation|endocardium development|protein phosphorylation|protein phosphorylation|apoptotic process|signal transduction|central nervous system development|negative regulation of cell proliferation|phosphorylation|peptidyl-serine phosphorylation|signal transduction by phosphorylation|keratinocyte differentiation|hippo signaling|hippo signaling|hippo signaling|intracellular signal transduction|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of organ growth|protein autophosphorylation|primitive hemopoiesis|cell differentiation involved in embryonic placenta development|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|hepatocyte apoptotic process|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|transcription factor binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|protein homodimerization activity|metal ion binding|protein dimerization activity|",10,1.1,2.23,10,1.1,23.2,1.1,25.1,25.1,0.0402,0,0,0.7,2
ENSMUSG00000033029,1700088E04RIK,RIKEN cDNA 1700088E04 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.211,10,0.7,26.3,0.7,24.9,24.9,0.0415,0,0,0.4,1.6
ENSMUSG00000031309,RPS6KA3,ribosomal protein S6 kinase polypeptide 3,nucleus|cytoplasm|,toll-like receptor signaling pathway|protein phosphorylation|response to stress|cell cycle|phosphorylation|response to lipopolysaccharide|intracellular signal transduction|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of transcription from RNA polymerase II promoter|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|",9,0.8,2.56,10,-1.6,27.7,-1.6,24.7,-24.7,0.0429,0,0,-3,-0.6
ENSMUSG00000003526,PRODH,proline dehydrogenase,mitochondrion|mitochondrion|mitochondrial inner membrane|,proline metabolic process|proline catabolic process|oxidation-reduction process|,proline dehydrogenase activity|proline dehydrogenase activity|oxidoreductase activity|amino acid binding|FAD binding|,10,0,0,10,0.7,27.6,0.7,24.6,24.6,0.0436,0,0,0.4,1.7
ENSMUSG00000038696,MAPKAP1,mitogen-activated protein kinase associated protein 1,nucleus|Golgi apparatus|plasma membrane|membrane|cytoplasmic vesicle|,response to stress|negative regulation of Ras protein signal transduction|,"protein binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|Ras GTPase binding|phosphatidylinositol-3,4-bisphosphate binding|phosphatidic acid binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0,0,10,1.3,27.4,1.3,24.6,24.6,0.0436,0,0,0.7,2
ENSMUSG00000025007,ALDH18A1,"aldehyde dehydrogenase 18 family, member A1",cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,glutamate metabolic process|proline biosynthetic process|ornithine biosynthetic process|metabolic process|cellular amino acid biosynthetic process|phosphorylation|citrulline biosynthetic process|oxidation-reduction process|,"nucleotide binding|catalytic activity|glutamate 5-kinase activity|glutamate 5-kinase activity|glutamate-5-semialdehyde dehydrogenase activity|ATP binding|kinase activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|transferase activity|poly(A) RNA binding|",10,0.6,5.48,10,1.6,23.6,1.5,24.4,24.4,0.0449,0,0,0.8,2.7
ENSMUSG00000020810,CYGB,cytoglobin,cytoplasm|neuron projection|neuronal cell body|,transport|response to oxidative stress|response to oxidative stress|oxygen transport|oxidation-reduction process|oxidation-reduction process|,peroxidase activity|peroxidase activity|oxygen transporter activity|iron ion binding|oxygen binding|heme binding|metal ion binding|,10,-0.8,2.91,10,1.3,23.6,1.2,24.3,24.3,0.0455,0,0,0.8,2
ENSMUSG00000030867,PLK1,polo-like kinase 1,"chromosome, centromeric region|kinetochore|spindle pole|condensed nuclear chromosome outer kinetochore|nucleus|chromosome|nucleolus|cytoplasm|centrosome|spindle|cytoskeleton|spindle microtubule|microtubule cytoskeleton|midbody|spindle midzone|",mitotic sister chromatid segregation|G2/M transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|mitotic cytokinesis|cytokinesis|microtubule bundle formation|protein phosphorylation|protein phosphorylation|cell cycle|mitotic nuclear division|activation of mitotic anaphase-promoting complex activity|mitotic spindle assembly checkpoint|regulation of mitotic cell cycle|positive regulation of peptidyl-threonine phosphorylation|phosphorylation|protein ubiquitination|peptidyl-serine phosphorylation|regulation of mitotic metaphase/anaphase transition|G2 DNA damage checkpoint|protein destabilization|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|polar body extrusion after meiotic divisions|negative regulation of apoptotic process|regulation of protein binding|establishment of protein localization|negative regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of proteolysis|centrosome organization|cell division|positive regulation of ubiquitin-protein transferase activity|protein localization to chromatin|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|microtubule binding|anaphase-promoting complex binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|",5,-0.4,3.79,4,1.3,26.7,1.3,24.3,24.3,0.0455,0,0,0.8,2
ENSMUSG00000031231,COX7B,cytochrome c oxidase subunit VIIb,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain|membrane|integral component of membrane|,central nervous system development|,molecular_function|cytochrome-c oxidase activity|,8,0.2,0.522,7,1.1,26.3,1.1,24.1,24.1,0.0474,0,0,0.5,2
ENSMUSG00000003119,CDK12,cyclin-dependent kinase 12,cyclin K-CDK12 complex|nucleus|nucleolus|nuclear speck|nuclear cyclin-dependent protein kinase holoenzyme complex|,mRNA processing|protein phosphorylation|RNA splicing|phosphorylation|regulation of MAP kinase activity|protein autophosphorylation|phosphorylation of RNA polymerase II C-terminal domain|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|",10,0.9,8.93,10,1,15.5,1,24,24,0.0481,0,0,0.5,1.7
ENSMUSG00000034218,ATM,ataxia telangiectasia mutated,"chromosome, telomeric region|intracellular|nucleus|nucleus|cytoplasm|spindle|cytoplasmic vesicle|","DNA damage checkpoint|telomere maintenance|response to hypoxia|somitogenesis|pre-B cell allelic exclusion|DNA repair|DNA repair|protein phosphorylation|protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|DNA damage induced protein phosphorylation|cell cycle|cell cycle arrest|mitotic spindle assembly checkpoint|female gamete generation|brain development|heart development|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|response to ionizing radiation|response to ionizing radiation|phosphorylation|histone phosphorylation|peptidyl-serine phosphorylation|negative regulation of B cell proliferation|histone-serine phosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|lipoprotein catabolic process|positive regulation of apoptotic process|positive regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of neuron apoptotic process|protein autophosphorylation|phosphatidylinositol phosphorylation|oocyte development|neuron apoptotic process|regulation of cell cycle|histone mRNA catabolic process|cellular response to gamma radiation|signal transduction involved in mitotic G2 DNA damage checkpoint|replicative senescence|","nucleotide binding|DNA binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|DNA-dependent protein kinase activity|protein binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|protein complex binding|histone serine kinase activity|protein dimerization activity|protein N-terminus binding|",9,0.5,4.67,10,1.5,24,1.3,24,24,0.0481,0,0,0.7,2.6
ENSMUSG00000020561,TWISTNB,TWIST neighbor,nucleus|nucleolus|DNA-directed RNA polymerase I complex|microtubule cytoskeleton|,"transcription, DNA-templated|",RNA polymerase I activity|DNA-directed RNA polymerase activity|,8,-0.4,2.47,7,1,24,0.8,23.2,23.2,0.055,0,0,0.5,1.8
ENSMUSG00000038976,PPP1R9B,"protein phosphatase 1, regulatory subunit 9B",intracellular|nucleus|nucleoplasm|cytoplasm|cytoskeleton|plasma membrane|membrane|lamellipodium|cell junction|filopodium|filopodium|cortical actin cytoskeleton|ruffle membrane|cell projection|synapse|,regulation of protein phosphorylation|actin filament organization|multicellular organismal development|nervous system development|dendrite development|cell migration|calcium-mediated signaling|actin cytoskeleton organization|cell differentiation|negative regulation of cell growth|filopodium assembly|cellular response to morphine|regulation of opioid receptor signaling pathway|,actin binding|protein binding|,10,0,0,10,1.1,26.2,1.1,23.2,23.2,0.055,0,0,0.4,1.9
ENSMUSG00000046062,PPP1R15B,"protein phosphatase 1, regulatory (inhibitor) subunit 15b",protein phosphatase type 1 complex|,regulation of translation|regulation of translational initiation|response to oxidative stress|response to oxidative stress|ER overload response|ER overload response|dephosphorylation|response to endoplasmic reticulum stress|response to hydrogen peroxide|,protein serine/threonine phosphatase activity|translation regulator activity|,9,0,0,9,1.4,26.4,1.4,23.2,23.2,0.055,0,0,0.9,2.9
ENSMUSG00000024369,NELFE,"negative elongation factor complex member E, Rdbp",nucleus|NELF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription elongation from RNA polymerase II promoter|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|poly(A) RNA binding|,6,0.1,0.0684,6,1.1,25.3,1.1,23,23,0.0569,0,0,0.6,2
ENSMUSG00000023903,MMP25,matrix metallopeptidase 25,plasma membrane|cell surface|membrane|integral component of membrane|extracellular matrix|anchored component of membrane|,proteolysis|inflammatory response|positive regulation of peptidase activity|hard palate development|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|peptidase activator activity|hydrolase activity|metal ion binding|,10,-0.3,1.21,10,1.2,24.8,1.2,22.9,22.9,0.0579,0,0,0.5,1.9
ENSMUSG00000026709,DARS2,aspartyl-tRNA synthetase 2 (mitochondrial),nucleus|cytoplasm|mitochondrion|mitochondrion|,translation|tRNA aminoacylation for protein translation|tRNA aminoacylation|,nucleotide binding|nucleic acid binding|aminoacyl-tRNA ligase activity|aspartate-tRNA ligase activity|ATP binding|ligase activity|protein homodimerization activity|aspartate-tRNA(Asn) ligase activity|,5,1.9,25.1,5,-0.3,1.28,1.8,22.5,22.5,0.0623,0,0,1.3,3
ENSMUSG00000037989,WNK2,WNK lysine deficient protein kinase 2,cytoplasm|plasma membrane|membrane|,protein phosphorylation|protein phosphorylation|negative regulation of cell proliferation|phosphorylation|protein autophosphorylation|negative regulation of ERK1 and ERK2 cascade|regulation of ion homeostasis|positive regulation of sodium ion transmembrane transporter activity|,"nucleotide binding|molecular_function|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,0.764,10,1.5,24.6,1.5,22.4,22.4,0.0634,0,0,0.8,2.8
ENSMUSG00000027438,NAPB,N-ethylmaleimide sensitive fusion protein attachment protein beta,membrane|synaptobrevin 2-SNAP-25-syntaxin-1a complex|,"transport|intracellular protein transport|regulation of synaptic vesicle priming|protein transport|vesicle-mediated transport|synaptic transmission, glutamatergic|SNARE complex disassembly|",protein binding|syntaxin binding|,10,0.4,1.74,10,1.2,23.7,1.2,22.3,22.3,0.0645,0,0,0.5,1.9
ENSMUSG00000028862,MAP3K6,mitogen-activated protein kinase kinase kinase 6,None,MAPK cascade|activation of MAPKK activity|activation of MAPKK activity|protein phosphorylation|protein phosphorylation|phosphorylation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0,0,10,1.2,25.1,1.2,22.3,22.3,0.0645,0,0,0.5,1.9
ENSMUSG00000024335,BRD2,bromodomain containing 2,nucleus|cytoplasm|,"nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|chromatin modification|",chromatin binding|lysine-acetylated histone binding|,8,0.7,9.39,8,0.9,13.3,0.7,22.2,22.2,0.0657,0,0,0.3,1.3
ENSMUSG00000024387,CSNK2B,"casein kinase 2, beta polypeptide",nucleus|cytoplasm|plasma membrane|protein kinase CK2 complex|PcG protein complex|extracellular vesicular exosome|,positive regulation of pathway-restricted SMAD protein phosphorylation|Wnt signaling pathway|phosphorylation|positive regulation of activin receptor signaling pathway|adiponectin-activated signaling pathway|negative regulation of blood vessel endothelial cell migration|endothelial tube morphogenesis|,receptor binding|protein binding|transcription factor binding|kinase activity|transferase activity|protein kinase regulator activity|protein domain specific binding|identical protein binding|metal ion binding|,8,-1.2,12.7,8,-0.7,11,-0.7,22,-22,0.0682,0,0,-1.6,-0.5
ENSMUSG00000014932,YES1,Yamaguchi sarcoma viral (v-yes) oncogene homolog 1,cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|membrane|extracellular vesicular exosome|,protein phosphorylation|glucose transport|phosphorylation|peptidyl-tyrosine phosphorylation|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|epidermal growth factor receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|ion channel binding|",9,0.4,0.517,10,1.2,23.7,1.2,21.8,21.8,0.0708,0,0,0.6,2
ENSMUSG00000031644,NEK1,NIMA (never in mitosis gene a)-related expressed kinase 1,pericentriolar material|nucleus|cytoplasm|centrosome|centrosome|cytoskeleton|,protein phosphorylation|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|response to ionizing radiation|phosphorylation|cell projection organization|cilium assembly|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",9,0.4,2.41,9,0.8,20.8,0.6,21.5,21.5,0.0749,0,0,0.3,1.3
ENSMUSG00000004902,SLC25A18,"solute carrier family 25 (mitochondrial carrier), member 18",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,0.2,1.1,10,1.2,23.7,1.2,21.3,21.3,0.0779,0,0,0.6,2
ENSMUSG00000032827,PPP1R9A,"protein phosphatase 1, regulatory (inhibitor) subunit 9A",intracellular|cytoskeleton|filopodium|growth cone|cortical actin cytoskeleton|dendritic spine|,actin filament organization|calcium-mediated signaling|neuron projection development|,protein binding|actin filament binding|,10,0,0,10,1.3,24.5,1.3,21.3,21.3,0.0779,0,0,0.7,2
ENSMUSG00000042244,PGLYRP3,peptidoglycan recognition protein 3,cellular_component|extracellular region|,pattern recognition receptor signaling pathway|immune system process|peptidoglycan catabolic process|detection of bacterium|negative regulation of interferon-gamma production|negative regulation of natural killer cell differentiation involved in immune response|defense response to bacterium|growth of symbiont in host|innate immune response|defense response to Gram-positive bacterium|,zinc ion binding|N-acetylmuramoyl-L-alanine amidase activity|peptidoglycan receptor activity|peptidoglycan binding|,10,-0.3,0.642,10,1.5,24.7,1.5,21.2,21.2,0.0796,0,0,1,3
ENSMUSG00000016346,KCNQ2,"potassium voltage-gated channel, subfamily Q, member 2",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|node of Ranvier|axon initial segment|protein complex|,transport|ion transport|potassium ion transport|transmission of nerve impulse|regulation of ion transmembrane transport|transmembrane transport|membrane hyperpolarization|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|ankyrin binding|protein N-terminus binding|,9,-0.8,0.88,9,1.5,24.3,1.5,21,21,0.0827,0,0,1,3
ENSMUSG00000022214,DCAF11,DDB1 and CUL4 associated factor 11,Cul4-RING E3 ubiquitin ligase complex|,biological_process|,molecular_function|,10,0,0,10,-1.6,24.2,-1.6,20.9,-20.9,0.0841,0,0,-3,-1
ENSMUSG00000026322,HTR4,5 hydroxytryptamine (serotonin) receptor 4,cytoplasm|endosome|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|serotonin receptor signaling pathway|gamma-aminobutyric acid signaling pathway|synaptic transmission|positive regulation of cell proliferation|regulation of appetite|,signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|protein binding|,9,-0.1,0.163,9,1.5,23.7,1.5,20.8,20.8,0.0859,0,0,1,3
ENSMUSG00000023982,GUCA1A,guanylate cyclase activator 1a (retina),photoreceptor outer segment|photoreceptor inner segment|plasma membrane|membrane|,visual perception|phototransduction|positive regulation of cGMP biosynthetic process|regulation of guanylate cyclase activity|positive regulation of guanylate cyclase activity|positive regulation of guanylate cyclase activity|response to stimulus|,calcium ion binding|calcium sensitive guanylate cyclase activator activity|calcium sensitive guanylate cyclase activator activity|guanylate cyclase regulator activity|metal ion binding|,10,1.1,2.57,9,-1.5,23.4,-1.5,20.8,-20.8,0.0859,0,0,-3,-1
ENSMUSG00000058499,PIP,prolactin induced protein,extracellular region|extracellular space|nucleus|apical plasma membrane|extracellular vesicular exosome|,detection of chemical stimulus involved in sensory perception of bitter taste|regulation of immune system process|proteolysis|positive regulation of gene expression|negative regulation of T cell apoptotic process|,glycoprotein binding|aspartic-type endopeptidase activity|protein binding|IgG binding|protein dimerization activity|,9,-1,13.1,9,1.5,23.6,1.4,20.8,20.8,0.0859,0,0,0.8,3
ENSMUSG00000030697,PPP4C,"protein phosphatase 4, catalytic subunit",nucleus|nucleus|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|protein phosphatase 4 complex|,protein phosphorylation|regulation of double-strand break repair via homologous recombination|dephosphorylation|dephosphorylation|signal transduction by phosphorylation|NIK/NF-kappaB signaling|,NF-kappaB-inducing kinase activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein serine/threonine phosphatase activity|protein binding|hydrolase activity|metal ion binding|,9,1.2,13.3,9,0.7,10.1,1,20.8,20.8,0.0859,0,0,0.5,1.6
ENSMUSG00000021721,HTR1A,5-hydroxytryptamine (serotonin) receptor 1A,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|neuronal cell body|axon hillock|,behavioral fear response|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting serotonin receptor signaling pathway|serotonin receptor signaling pathway|serotonin receptor signaling pathway|serotonin receptor signaling pathway|behavior|cell proliferation|regulation of serotonin secretion|positive regulation of microtubule depolymerization|exploration behavior|regulation of dopamine metabolic process|vasoconstriction|serotonin metabolic process|regulation of hormone secretion|regulation of behavior|regulation of feeding behavior|N-methyl-D-aspartate receptor clustering|,G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|serotonin receptor activity|serotonin receptor activity|drug binding|serotonin binding|,10,0.4,0.915,10,1.1,22.2,0.7,20.8,20.8,0.0859,0,0,0.4,1.9
ENSMUSG00000025194,ABCC2,"ATP-binding cassette, sub-family C (CFTR/MRP), member 2",plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|intercellular canaliculus|,transport|drug transmembrane transport|prostaglandin transport|cellular chloride ion homeostasis|response to drug|response to estrogen|transmembrane transport|thyroid hormone transport|,"nucleotide binding|transporter activity|protein binding|ATP binding|ATPase activity|protein domain specific binding|ATPase activity, coupled to transmembrane movement of substances|",10,1.6,23.7,10,0,0,1.6,20.7,20.7,0.0875,0,0,0.7,3
ENSMUSG00000020159,GABRP,"gamma-aminobutyric acid (GABA) A receptor, pi",plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|signal transduction|,GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|,10,0.5,0.676,10,-1.8,24,-1.8,20.7,-20.7,0.0875,0,0,-3,-1.3
ENSMUSG00000016179,CAMK1G,calcium/calmodulin-dependent protein kinase I gamma,cytoplasm|Golgi apparatus|plasma membrane|calcium- and calmodulin-dependent protein kinase complex|endomembrane system|membrane|neuron projection|,protein phosphorylation|protein phosphorylation|metabolic process|phosphorylation|,"nucleotide binding|catalytic activity|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin-dependent protein kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,-0.3,0.798,10,1.3,23.8,1.3,20.7,20.7,0.0875,0,0,0.7,2
ENSMUSG00000042662,DUSP15,dual specificity phosphatase-like 15,cellular_component|,protein dephosphorylation|transforming growth factor beta receptor signaling pathway|dephosphorylation|regulation of cell proliferation|positive regulation of JNK cascade|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,-0.1,0.0907,10,1.3,23.8,1.3,20.7,20.7,0.0875,0,0,0.8,2
ENSMUSG00000028811,YARS,tyrosyl-tRNA synthetase,nucleus|cytoplasm|,translation|tRNA aminoacylation for protein translation|tyrosyl-tRNA aminoacylation|biological_process|,tRNA binding|nucleotide binding|RNA binding|aminoacyl-tRNA ligase activity|tyrosine-tRNA ligase activity|ATP binding|ligase activity|poly(A) RNA binding|,4,1.3,11.2,5,0.9,10.7,1.1,20.6,20.6,0.0892,0,0,0.6,1.9
ENSMUSG00000057181,5730455P16RIK,RIKEN cDNA 5730455P16 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.349,10,1.2,23.8,1.1,20.6,20.6,0.0892,0,0,0.6,2
ENSMUSG00000031299,PDHA1,pyruvate dehydrogenase E1 alpha 1,nucleus|mitochondrion|mitochondrion|intracellular membrane-bounded organelle|pyruvate dehydrogenase complex|,carbohydrate metabolic process|glucose metabolic process|acetyl-CoA biosynthetic process from pyruvate|glycolytic process|tricarboxylic acid cycle|metabolic process|oxidation-reduction process|,"pyruvate dehydrogenase activity|pyruvate dehydrogenase activity|pyruvate dehydrogenase (acetyl-transferring) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor|",10,-0.8,19.6,10,-0.3,1.73,-0.7,20.4,-20.4,0.0931,0,0,-1.4,-0.4
ENSMUSG00000041323,AK7,adenylate kinase 7,nucleus|cytoplasm|,inflammatory response to antigenic stimulus|epithelial cilium movement|nucleobase-containing compound metabolic process|nucleoside diphosphate phosphorylation|spermatogenesis|brain development|nucleoside triphosphate biosynthetic process|phosphorylation|cell projection organization|axoneme assembly|,nucleotide binding|adenylate kinase activity|cytidylate kinase activity|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|nucleobase-containing compound kinase activity|,10,0.1,0.0518,10,1,23,0.7,20.2,20.2,0.0972,0,0,0.3,1.8
ENSMUSG00000031297,SLC7A3,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 3",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|arginine transport|arginine transport|lysine transport|lysine transport|ornithine transport|regulation of TOR signaling|L-alpha-amino acid transmembrane transport|,L-ornithine transmembrane transporter activity|amino acid transmembrane transporter activity|arginine transmembrane transporter activity|arginine transmembrane transporter activity|L-lysine transmembrane transporter activity|L-lysine transmembrane transporter activity|cationic amino acid transmembrane transporter activity|cationic amino acid transmembrane transporter activity|,10,-0.3,1.74,10,1,21.1,0.9,20,20,0.101,0,0,0.4,1.8
ENSMUSG00000036112,METAP2,methionine aminopeptidase 2,cytoplasm|plasma membrane|,proteolysis|protein processing|peptidyl-methionine modification|N-terminal protein amino acid modification|,aminopeptidase activity|protein binding|peptidase activity|metalloexopeptidase activity|hydrolase activity|poly(A) RNA binding|metal ion binding|,8,1,20.2,8,0.2,1.83,0.9,19.8,19.8,0.105,0,0,0.5,1.6
ENSMUSG00000003518,DUSP3,dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related),immunological synapse|nucleus|cytosol|cytosol|extracellular vesicular exosome|,inactivation of MAPK activity|inactivation of MAPK activity|in utero embryonic development|protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|negative regulation of MAPK cascade|positive regulation of mitotic cell cycle|positive regulation of mitotic cell cycle|negative regulation of JNK cascade|negative regulation of JNK cascade|negative regulation of T cell receptor signaling pathway|negative regulation of T cell receptor signaling pathway|negative regulation of T cell activation|negative regulation of T cell activation|negative regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 and ERK2 cascade|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase phosphatase activity|MAP kinase phosphatase activity|,10,0.1,0.463,10,1.1,22.3,1,19.7,19.7,0.107,0,0,0.3,1.9
ENSMUSG00000028280,GABRR1,"gamma-aminobutyric acid (GABA) C receptor, subunit rho 1",plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|signal transduction|,GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|GABA receptor activity|protein domain specific binding|protein homodimerization activity|protein heterodimerization activity|,10,-0.2,1.19,10,1.8,23.1,1.8,19.6,19.6,0.109,0,0,1.3,3
ENSMUSG00000026579,F5,coagulation factor V,extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|membrane|platelet alpha granule|,proteolysis|cell adhesion|blood coagulation|blood coagulation|blood coagulation|hemostasis|blood circulation|,serine-type endopeptidase activity|copper ion binding|metal ion binding|,10,0,0,10,-1.5,21.8,-1.4,19.6,-19.6,0.109,0,0,-3,-0.9
ENSMUSG00000024538,PPIC,peptidylprolyl isomerase C,cytoplasm|extracellular vesicular exosome|,protein peptidyl-prolyl isomerization|protein folding|,peptidyl-prolyl cis-trans isomerase activity|protein binding|isomerase activity|peptide binding|,10,0.2,0.523,10,-1.5,23,-1.5,19.5,-19.5,0.111,0,0,-3,-1
ENSMUSG00000020612,PRKAR1A,"protein kinase, cAMP dependent regulatory, type I, alpha",cytoplasm|cytoplasm|plasma membrane|cAMP-dependent protein kinase complex|membrane|membrane|AMP-activated protein kinase complex|neuromuscular junction|protein complex|,mesoderm formation|regulation of protein phosphorylation|protein phosphorylation|negative regulation of protein kinase activity|heart development|cell proliferation|organ morphogenesis|phosphorylation|sarcomere organization|regulation of protein kinase activity|regulation of protein kinase activity|cardiac muscle cell proliferation|negative regulation of cAMP-dependent protein kinase activity|,nucleotide binding|cAMP-dependent protein kinase inhibitor activity|protein binding|cAMP-dependent protein kinase regulator activity|cAMP-dependent protein kinase regulator activity|cAMP-dependent protein kinase regulator activity|cAMP-dependent protein kinase regulator activity|kinase activity|transferase activity|cAMP binding|ubiquitin protein ligase binding|protein kinase A catalytic subunit binding|,7,-0.5,2.36,7,1,21,0.7,19.5,19.5,0.111,0,0,0.4,1.8
ENSMUSG00000041720,PI4KA,"phosphatidylinositol 4-kinase, catalytic, alpha polypeptide",plasma membrane|membrane|Golgi-associated vesicle membrane|extracellular vesicular exosome|,phosphorylation|phosphatidylinositol phosphorylation|,1-phosphatidylinositol 4-kinase activity|1-phosphatidylinositol 4-kinase activity|kinase activity|transferase activity|,9,-1.2,10.9,9,-0.6,9.96,-0.6,19.4,-19.4,0.113,0,0,-1.4,-0.4
ENSMUSG00000016427,NDUFA1,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|mitochondrial membrane|respiratory chain|,transport|oxidation-reduction process|,None,6,1.3,17.4,5,0.5,5.2,1.2,18.9,18.9,0.121,0,0,0.7,2
ENSMUSG00000029613,EIF2AK1,eukaryotic translation initiation factor 2 alpha kinase 1,cytoplasm|,regulation of translation|protein phosphorylation|negative regulation of cell proliferation|regulation of eIF2 alpha phosphorylation by heme|phosphorylation|negative regulation of translation|protoporphyrinogen IX metabolic process|regulation of hemoglobin biosynthetic process|negative regulation of hemoglobin biosynthetic process|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|heme binding|protein homodimerization activity|",10,2.3,21.9,10,-0.3,1.23,2.3,18.8,18.8,0.122,0,0,1.8,4
ENSMUSG00000012519,MLKL,mixed lineage kinase domain-like,cytoplasm|plasma membrane|membrane|,protein phosphorylation|programmed cell death|protein homotrimerization|necroptotic process|necroptotic process|,"nucleotide binding|ATP binding|ATP binding|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein complex binding|",10,-0.2,1.06,10,0.9,21.5,0.9,18.6,18.6,0.124,0,0,0.4,1.8
ENSMUSG00000020715,ERN1,endoplasmic reticulum (ER) to nucleus signalling 1,nuclear inner membrane|mitochondrion|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|protein phosphorylation|apoptotic process|response to unfolded protein|activation of signaling protein activity involved in unfolded protein response|cell cycle arrest|metabolic process|phosphorylation|endoplasmic reticulum unfolded protein response|protein autophosphorylation|HAC1-type intron splice site recognition and cleavage|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|RNA phosphodiester bond hydrolysis, endonucleolytic|RNA phosphodiester bond hydrolysis, endonucleolytic|positive regulation of endoplasmic reticulum unfolded protein response|","nucleotide binding|magnesium ion binding|catalytic activity|endonuclease activity|endoribonuclease activity|endoribonuclease activity|ribonuclease activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|bidentate ribonuclease III activity|transferase activity|transferase activity, transferring phosphorus-containing groups|hydrolase activity|enzyme binding|identical protein binding|metal ion binding|",10,-1,3.02,9,-1.3,16.5,-1.2,18.5,-18.5,0.125,0,0,-1.9,-0.6
ENSMUSG00000060923,ACYP2,"acylphosphatase 2, muscle type",mitochondrion|,biological_process|,acylphosphatase activity|hydrolase activity|,10,-0.9,2.59,10,1,21.1,0.7,18.5,18.5,0.125,0,0,0.3,1.8
ENSMUSG00000028792,AK2,adenylate kinase 2,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|cytosol|sperm flagellum|extracellular vesicular exosome|sperm mitochondrial sheath|,nucleobase-containing compound metabolic process|ADP biosynthetic process|phosphorylation|AMP metabolic process|ATP metabolic process|dATP metabolic process|nucleotide phosphorylation|,"nucleotide binding|adenylate kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, phosphate group as acceptor|nucleobase-containing compound kinase activity|",9,-1.6,15.1,8,0.9,6.84,0.8,18.5,18.5,0.125,0,0,-1.7,2
ENSMUSG00000032113,CHEK1,checkpoint kinase 1,"chromosome, telomeric region|chromatin|condensed nuclear chromosome|extracellular space|nucleus|nucleus|replication fork|cytoplasm|centrosome|cytoskeleton|intracellular membrane-bounded organelle|",DNA damage checkpoint|DNA damage checkpoint|DNA damage checkpoint|G2/M transition of mitotic cell cycle|DNA repair|DNA repair|protein phosphorylation|protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|DNA damage induced protein phosphorylation|cell cycle|regulation of gene expression|regulation of double-strand break repair via homologous recombination|regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage|negative regulation of G2/M transition of mitotic cell cycle|phosphorylation|peptidyl-threonine phosphorylation|G2 DNA damage checkpoint|histone H3-T11 phosphorylation|histone H3-T11 phosphorylation|regulation of cell proliferation|negative regulation of mitosis|regulation of mitotic centrosome separation|chromatin-mediated maintenance of transcription|negative regulation of DNA biosynthetic process|regulation of histone H3-K9 acetylation|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|histone kinase activity (H3-T11 specific)|histone kinase activity (H3-T11 specific)|",8,-1.2,18.6,6,1,14.2,-1.1,17.9,-17.9,0.131,0,0,-2,1.6
ENSMUSG00000010342,TEX14,testis expressed gene 14,"chromosome, centromeric region|kinetochore|cell|chromosome|cytoplasm|midbody|intercellular bridge|",protein phosphorylation|cell cycle|mitotic nuclear division|mitotic spindle assembly checkpoint|male meiosis|attachment of spindle microtubules to kinetochore|negative regulation of protein binding|negative regulation of cytokinesis|intercellular bridge organization|cell division|mitotic sister chromatid separation|,"nucleotide binding|protein kinase activity|protein binding|ATP binding|transferase activity, transferring phosphorus-containing groups|protein kinase binding|",10,1.5,18.4,10,-0.3,1.58,1.4,17.8,17.8,0.132,0,0,0.5,2.9
ENSMUSG00000053604,RPIA,ribose 5-phosphate isomerase A,intracellular membrane-bounded organelle|,"pentose-phosphate shunt|pentose-phosphate shunt, non-oxidative branch|ribose phosphate metabolic process|",ribose-5-phosphate isomerase activity|ribose-5-phosphate isomerase activity|isomerase activity|carbohydrate binding|monosaccharide binding|,8,-1.4,20.5,8,0.7,1.11,-1.4,17.5,-17.5,0.134,0,0,-2,-0.6
ENSMUSG00000029700,SLC13A1,"solute carrier family 13 (sodium/sulfate symporters), member 1",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|sulfate transport|sulfate transport|sodium ion transmembrane transport|transmembrane transport|sulfate transmembrane transport|,transporter activity|secondary active sulfate transmembrane transporter activity|symporter activity|sodium:sulfate symporter activity|,10,0.5,0.327,10,0.9,18.4,0.9,17.4,17.4,0.135,0,0,0.4,1.7
ENSMUSG00000032231,ANXA2,annexin A2,stress fiber|ruffle|extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|nucleus|cytoplasm|cytoplasm|lysosomal membrane|early endosome|lipid particle|plasma membrane|cell cortex|cell surface|membrane|membrane|extrinsic component of plasma membrane|cell junction|midbody|late endosome membrane|vesicle|myelin sheath adaxonal region|sarcolemma|Schmidt-Lanterman incisure|protein complex|macropinosome|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,angiogenesis|membrane raft assembly|positive regulation of protein phosphorylation|membrane budding|body fluid secretion|collagen fibril organization|positive regulation of vesicle fusion|osteoclast development|fibrinolysis|negative regulation of catalytic activity|positive regulation of fibroblast proliferation|positive regulation of binding|protein heterotetramerization|cellular response to acid|protein targeting to plasma membrane|,"phospholipase inhibitor activity|calcium ion binding|protein binding|calcium-dependent phospholipid binding|phosphatidylinositol-4,5-bisphosphate binding|cytoskeletal protein binding|Rab GTPase binding|phospholipase A2 inhibitor activity|S100 protein binding|poly(A) RNA binding|calcium-dependent protein binding|",10,0.5,1.27,10,1,17.6,0.8,17.2,17.2,0.137,0,0,0.4,1.9
ENSMUSG00000003273,CAR11,carbonic anhydrase 11,extracellular region|basolateral plasma membrane|,biological_process|,None,10,-1.5,20.4,9,0.1,0.263,-1.5,17,-17,0.138,0,0,-3,-1
ENSMUSG00000006058,SNF8,"SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)",nucleus|transcription factor complex|cytoplasm|endosome|membrane|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transport|protein transport|",transcription factor binding|protein homodimerization activity|,9,-0.8,12.4,10,-0.7,4.98,-0.8,16.9,-16.9,0.139,0,0,-1.4,-0.4
ENSMUSG00000027177,HIPK3,homeodomain interacting protein kinase 3,nucleus|nucleus|cytoplasm|cytoplasm|PML body|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|apoptotic process|mRNA transcription|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|negative regulation of apoptotic process|positive regulation of DNA binding|negative regulation of JUN kinase activity|","nucleotide binding|transcription corepressor activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",8,0.1,0.0517,8,1,18.8,1,16.6,16.6,0.141,0,0,0.3,1.9
ENSMUSG00000030647,NDUFC2,"NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2",cytoplasm|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|respiratory chain|,"mitochondrial electron transport, NADH to ubiquinone|transport|oxidation-reduction process|",NADH dehydrogenase (ubiquinone) activity|,9,-0.3,1.36,7,1,18.6,1,16.3,16.3,0.143,0,0,0.3,2
ENSMUSG00000020456,OGDH,oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide),mitochondrion|mitochondrion|oxoglutarate dehydrogenase complex|,glycolytic process|tricarboxylic acid cycle|2-oxoglutarate metabolic process|succinyl-CoA metabolic process|NADH metabolic process|metabolic process|oxidation-reduction process|,"oxoglutarate dehydrogenase (succinyl-transferring) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor|thiamine pyrophosphate binding|heat shock protein binding|oxoglutarate dehydrogenase (NAD+) activity|metal ion binding|chaperone binding|",8,0.9,9.51,8,0.6,8.02,0.7,16.3,16.3,0.143,0,0,0.3,1.3
ENSMUSG00000022912,PROS1,protein S (alpha),extracellular region|extracellular space|protein complex|blood microparticle|,blood coagulation|hemostasis|fibrinolysis|positive regulation of phagocytosis|negative regulation of coagulation|,calcium ion binding|protein complex binding|,10,-1.6,16.4,10,-0.3,5.69,-0.6,15.9,-15.9,0.146,0,0,-2.4,-0.4
ENSMUSG00000000441,RAF1,v-raf-leukemia viral oncogene 1,nucleus|cytoplasm|mitochondrion|Golgi apparatus|cytosol|plasma membrane|plasma membrane|membrane|pseudopodium|,MAPK cascade|activation of MAPKK activity|response to hypoxia|protein phosphorylation|protein phosphorylation|signal transduction|negative regulation of cell proliferation|phosphorylation|cell differentiation|negative regulation of protein complex assembly|positive regulation of peptidyl-serine phosphorylation|somatic stem cell maintenance|intracellular signal transduction|negative regulation of apoptotic process|intermediate filament cytoskeleton organization|neurotrophin TRK receptor signaling pathway|death-inducing signaling complex assembly|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|receptor signaling protein activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Ras GTPase binding|mitogen-activated protein kinase kinase binding|identical protein binding|metal ion binding|protein heterodimerization activity|",8,1,5.73,8,0.8,10.4,0.9,15.6,15.6,0.148,0,0,0.3,1.6
ENSMUSG00000025869,NOP16,NOP16 nucleolar protein,nucleus|nucleolus|intracellular membrane-bounded organelle|,biological_process|,poly(A) RNA binding|,9,-0.8,4.56,9,-0.8,11.3,-0.8,15.4,-15.4,0.149,0,0,-1.5,-0.4
ENSMUSG00000037519,PPFIA1,"protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1",cytoplasm|focal adhesion|,negative regulation of stress fiber assembly|negative regulation of stress fiber assembly|negative regulation of establishment of protein localization to plasma membrane|,protein binding|,10,0.6,7.05,10,0.6,8.62,0.6,15.3,15.3,0.149,0,0,0.3,1.2
ENSMUSG00000031871,CDH5,cadherin 5,plasma membrane|cell-cell junction|cell-cell junction|tight junction|membrane|integral component of membrane|cell junction|cell periphery|,blood vessel maturation|cell adhesion|homophilic cell adhesion|negative regulation of cell proliferation|single organismal cell-cell adhesion|single organismal cell-cell adhesion|regulation of establishment of cell polarity|regulation of establishment of cell polarity|,receptor binding|calcium ion binding|protein binding|beta-catenin binding|protein phosphatase binding|ion channel binding|metal ion binding|,10,1.5,17.9,10,0.3,1.53,1.5,15.2,15.2,0.15,0,0,0.4,3
ENSMUSG00000031948,KARS,lysyl-tRNA synthetase,cytoplasm|mitochondrion|mitochondrion|microtubule cytoskeleton|aminoacyl-tRNA synthetase multienzyme complex|,translation|tRNA aminoacylation for protein translation|lysyl-tRNA aminoacylation|diadenosine tetraphosphate biosynthetic process|,tRNA binding|nucleotide binding|nucleic acid binding|aminoacyl-tRNA ligase activity|lysine-tRNA ligase activity|ATP binding|amino acid binding|ligase activity|metal ion binding|,8,-0.8,6.39,8,-0.6,9.55,-0.7,15,-15,0.151,0,0,-1.3,-0.3
ENSMUSG00000029777,GARS,glycyl-tRNA synthetase,nucleus|cytoplasm|mitochondrion|secretory granule|extracellular vesicular exosome|,translation|tRNA aminoacylation for protein translation|glycyl-tRNA aminoacylation|diadenosine tetraphosphate biosynthetic process|,nucleotide binding|aminoacyl-tRNA ligase activity|glycine-tRNA ligase activity|protein binding|ATP binding|ligase activity|protein dimerization activity|,10,1.4,18.3,9,-0.9,13,1.3,15,15,0.151,0,0,-0.6,3
ENSMUSG00000057069,ERO1LB,ERO1-like beta (S. cerevisiae),endoplasmic reticulum|membrane|,transport|4-hydroxyproline metabolic process|protein maturation by protein folding|protein maturation by protein folding|insulin processing|extracellular matrix organization|glucose homeostasis|cell redox homeostasis|oxidation-reduction process|,"protein disulfide isomerase activity|peptide-methionine (S)-S-oxide reductase activity|protein disulfide oxidoreductase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor|peptide-methionine (R)-S-oxide reductase activity|methionine-R-sulfoxide reductase activity|",10,-1.4,18.2,10,0.4,4.13,-1.4,14.9,-14.9,0.152,0,0,-2,-0.4
ENSMUSG00000004207,PSAP,prosaposin,extracellular region|extracellular space|mitochondrion|lysosome|extracellular vesicular exosome|,lipid metabolic process|sphingolipid metabolic process|regulation of lipid metabolic process|regulation of MAPK cascade|developmental growth|prostate gland growth|epithelial cell differentiation involved in prostate gland development|cellular response to organic substance|,None,10,0.3,2.17,10,0.5,13.3,0.5,14.7,14.7,0.153,0,0,0.3,1.1
ENSMUSG00000044018,MRPL50,mitochondrial ribosomal protein L50,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,8,-1.2,12.6,10,-0.7,4.05,-1.1,14.7,-14.7,0.153,0,0,-1.9,-0.6
ENSMUSG00000013663,PTEN,phosphatase and tensin homolog,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|plasma membrane|cytoplasmic side of plasma membrane|myelin sheath adaxonal region|cell projection|neuron projection|neuron projection|dendritic spine|Schmidt-Lanterman incisure|postsynaptic membrane|,angiogenesis|negative regulation of protein phosphorylation|regulation of B cell apoptotic process|protein dephosphorylation|lipid metabolic process|apoptotic process|activation of mitotic anaphase-promoting complex activity|activation of mitotic anaphase-promoting complex activity|neuron-neuron synaptic transmission|nervous system development|synapse assembly|central nervous system development|heart development|learning or memory|memory|locomotory behavior|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|regulation of neuron projection development|dephosphorylation|cell migration|dentate gyrus development|central nervous system neuron axonogenesis|negative regulation of cell migration|neuron projection development|negative regulation of myelination|regulation of protein stability|negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|central nervous system myelin maintenance|regulation of cellular component size|regulation of myeloid cell apoptotic process|multicellular organismal response to stress|social behavior|peptidyl-tyrosine dephosphorylation|maternal behavior|positive regulation of apoptotic process|negative regulation of apoptotic process|protein kinase B signaling|endothelial cell migration|locomotor rhythm|negative regulation of cell size|negative regulation of organ growth|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|platelet-derived growth factor receptor signaling pathway|cardiac muscle tissue development|forebrain morphogenesis|brain morphogenesis|negative regulation of epithelial cell proliferation|negative regulation of phagocytosis|negative regulation of axonogenesis|protein stabilization|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of cell cycle|negative regulation of focal adhesion assembly|negative regulation of protein kinase B signaling|negative regulation of protein kinase B signaling|rhythmic synaptic transmission|canonical Wnt signaling pathway|synapse maturation|prepulse inhibition|male mating behavior|long-term synaptic potentiation|long term synaptic depression|prostate gland growth|dendritic spine morphogenesis|negative regulation of dendritic spine morphogenesis|negative regulation of ribosome biogenesis|negative regulation of cell aging|negative regulation of excitatory postsynaptic membrane potential|presynaptic membrane assembly|postsynaptic density assembly|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of G1/S transition of mitotic cell cycle|positive regulation of excitatory postsynaptic membrane potential|negative regulation of synaptic vesicle clustering|positive regulation of apoptotic signaling pathway|,"magnesium ion binding|phosphatidylinositol-3-phosphatase activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|platelet-derived growth factor receptor binding|protein binding|protein tyrosine/serine/threonine phosphatase activity|anaphase-promoting complex binding|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity|hydrolase activity|phosphatase activity|enzyme binding|protein kinase binding|PDZ domain binding|inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity|phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity|",10,1.1,3.93,9,0.5,11.4,0.9,14.3,14.3,0.155,0,0,0.3,1.6
ENSMUSG00000029246,PPAT,phosphoribosyl pyrophosphate amidotransferase,None,purine nucleotide biosynthetic process|glutamine catabolic process|purine ribonucleoside monophosphate biosynthetic process|ribose phosphate metabolic process|protein homotetramerization|,"amidophosphoribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|iron-sulfur cluster binding|",5,-1.1,5.68,5,-0.8,9.59,-0.8,14.2,-14.2,0.156,0,0,-1.7,-0.4
ENSMUSG00000002012,PNCK,pregnancy upregulated non-ubiquitously expressed CaM kinase,nucleus|cytoplasm|calcium- and calmodulin-dependent protein kinase complex|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.4,15,10,0.4,1.36,1.3,14.2,14.2,0.156,0,0,0.3,2.5
ENSMUSG00000021302,GGPS1,geranylgeranyl diphosphate synthase 1,cytoplasm|,isoprenoid metabolic process|isoprenoid biosynthetic process|,"dimethylallyltranstransferase activity|farnesyltranstransferase activity|geranyltranstransferase activity|prenyltransferase activity|protein geranylgeranyltransferase activity|protein prenyltransferase activity|4-hydroxybenzoate octaprenyltransferase activity|protoheme IX farnesyltransferase activity|transferase activity|(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity|cadaverine aminopropyltransferase activity|agmatine aminopropyltransferase activity|1,4-dihydroxy-2-naphthoate octaprenyltransferase activity|metal ion binding|trans-pentaprenyltranstransferase activity|ATP dimethylallyltransferase activity|ADP dimethylallyltransferase activity|",6,1,8.99,5,-0.9,7.28,-0.8,14,-14,0.157,0,0,-2,1.2
ENSMUSG00000038763,ALPK3,alpha-kinase 3,nucleus|,protein phosphorylation|multicellular organismal development|heart development|phosphorylation|,"molecular_function|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|ATP binding|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,1.6,16.8,10,0.3,0.623,1.6,14,14,0.157,0,0,0.6,3
ENSMUSG00000021413,PRPF4B,PRP4 pre-mRNA processing factor 4 homolog B (yeast),nucleus|spliceosomal complex|chromosome|catalytic step 2 spliceosome|,mRNA processing|protein phosphorylation|RNA splicing|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|",10,-0.7,8.77,10,0.5,7.52,0.7,13.9,13.9,0.158,0,0,0.2,1.6
ENSMUSG00000020664,DLD,dihydrolipoamide dehydrogenase,nucleus|mitochondrion|mitochondrion|cilium|acrosomal matrix|oxoglutarate dehydrogenase complex|pyruvate dehydrogenase complex|,"acetyl-CoA biosynthetic process from pyruvate|2-oxoglutarate metabolic process|mitochondrial electron transport, NADH to ubiquinone|proteolysis|gastrulation|lipoate metabolic process|regulation of membrane potential|cell redox homeostasis|sperm capacitation|dihydrolipoamide metabolic process|oxidation-reduction process|","dihydrolipoyl dehydrogenase activity|dihydrolipoyl dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor|lipoamide binding|flavin adenine dinucleotide binding|NAD binding|",8,-1.7,7.9,7,-1,7.78,-1.7,13.4,-13.4,0.161,0,0,-3,0.8
ENSMUSG00000030800,PRSS8,"protease, serine 8 (prostasin)",extracellular region|extracellular space|extracellular space|plasma membrane|membrane|integral component of membrane|extrinsic component of plasma membrane|membrane raft|anchored component of plasma membrane|extracellular vesicular exosome|,hair follicle development|proteolysis|positive regulation of sodium ion transport|transepithelial transport|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|sodium channel regulator activity|sodium channel regulator activity|,10,-0.8,14.9,10,0.2,1.1,-0.7,13.2,-13.2,0.162,0,0,-1.8,-0.4
ENSMUSG00000073411,H2-D1,"histocompatibility 2, D region locus 1",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|plasma membrane|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,"positive regulation of T cell mediated cytotoxicity|immune system process|antigen processing and presentation of peptide antigen via MHC class I|antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent|immune response|antigen processing and presentation|",receptor binding|protein binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,-0.7,8.77,10,-0.7,4.67,-0.7,13.1,-13.1,0.163,0,0,-1.2,-0.3
ENSMUSG00000018334,KSR1,kinase suppressor of ras 1,cytoplasm|endoplasmic reticulum|membrane|membrane|,protein phosphorylation|phosphorylation|intracellular signal transduction|positive regulation of MAPK cascade|,"protein kinase activity|protein serine/threonine kinase activity|MAP-kinase scaffold activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase binding|metal ion binding|",10,0.7,1.34,10,0.5,12.3,0.6,13,13,0.164,0,0,0.2,1
ENSMUSG00000059183,MTFMT,mitochondrial methionyl-tRNA formyltransferase,mitochondrion|,translation|biosynthetic process|conversion of methionyl-tRNA to N-formyl-methionyl-tRNA|,"methionyl-tRNA formyltransferase activity|transferase activity|hydroxymethyl-, formyl- and related transferase activity|",10,-0.6,5.6,10,-0.9,8.05,-0.7,12.9,-12.9,0.165,0,0,-1.3,-0.2
ENSMUSG00000029148,NRBP1,nuclear receptor binding protein 1,cytoplasm|endomembrane system|membrane|cell projection|perinuclear region of cytoplasm|,protein phosphorylation|ER to Golgi vesicle-mediated transport|,"protein serine/threonine kinase activity|protein binding|transferase activity, transferring phosphorus-containing groups|identical protein binding|protein homodimerization activity|",9,1,11,9,0.4,6.14,0.5,12.6,12.6,0.167,0,0,0.3,1.5
ENSMUSG00000039671,ZMYND8,"zinc finger, MYND-type containing 8",cellular_component|,biological_process|phosphorylation|,molecular_function|kinase activity|transferase activity|metal ion binding|,10,0.9,4.07,10,0.7,9.1,0.7,12.5,12.5,0.168,0,0,0.3,1.4
ENSMUSG00000031633,SLC25A4,"solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4",nucleus|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial inner membrane|membrane|integral component of membrane|,transport|apoptotic mitochondrial changes|purine nucleoside transmembrane transport|ADP transport|ATP transport|ion transmembrane transport|transmembrane transport|negative regulation of necroptotic process|nucleotide transmembrane transport|positive regulation of oxidative phosphorylation uncoupler activity|,transporter activity|ATP:ADP antiporter activity|protein binding|enzyme binding|,10,-1.6,15.8,10,0,0,-1.6,12.4,-12.4,0.169,0,0,-3,-1
ENSMUSG00000025162,CSNK1D,"casein kinase 1, delta",nucleus|cytoplasm|Golgi apparatus|centrosome|spindle|cytoskeleton|spindle microtubule|plasma membrane|membrane|perinuclear region of cytoplasm|,positive regulation of protein phosphorylation|protein phosphorylation|protein phosphorylation|protein phosphorylation|Wnt signaling pathway|phosphorylation|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|circadian regulation of gene expression|regulation of circadian rhythm|rhythmic process|spindle assembly|positive regulation of canonical Wnt signaling pathway|,"nucleotide binding|glycoprotein binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|peptide binding|tau-protein kinase activity|phosphoprotein binding|",10,0.4,3.13,10,0.6,9.95,0.5,12.4,12.4,0.169,0,0,0.2,1
ENSMUSG00000030890,ILK,integrin linked kinase,stress fiber|intracellular|nucleus|cytoplasm|plasma membrane|cell-cell junction|focal adhesion|focal adhesion|focal adhesion|membrane|membrane|lamellipodium|cell junction|axon|extracellular matrix|cell projection|neuronal cell body|costamere|terminal bouton|dendritic shaft|protein complex|,"regulation of cell growth|branching involved in ureteric bud morphogenesis|positive regulation of cell-matrix adhesion|protein phosphorylation|negative regulation of protein kinase activity|cell cycle arrest|integrin-mediated signaling pathway|cell aging|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of signal transduction|negative regulation of cardiac muscle cell apoptotic process|fibroblast migration|Schwann cell development|negative regulation of smooth muscle cell migration|phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|nerve development|myelination in peripheral nervous system|cell projection organization|positive regulation of cell migration|positive regulation of BMP signaling pathway|myelin assembly|regulation of actin cytoskeleton organization|substrate adhesion-dependent cell spreading|positive regulation of phosphorylation|negative regulation of apoptotic process|extracellular fibril organization|positive regulation of MAP kinase activity|positive regulation of MAPK cascade|protein kinase B signaling|negative regulation of neuron apoptotic process|establishment or maintenance of epithelial cell apical/basal polarity|positive regulation of myoblast differentiation|positive regulation of osteoblast differentiation|positive regulation of axon extension|positive regulation of transcription, DNA-templated|negative regulation of smooth muscle cell proliferation|neuron projection morphogenesis|positive regulation of axonogenesis|positive regulation of dendrite morphogenesis|protein heterooligomerization|positive regulation of protein kinase B signaling|positive regulation of canonical Wnt signaling pathway|negative regulation of neural precursor cell proliferation|negative regulation of neural precursor cell proliferation|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|signal transducer activity|integrin binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SH3 domain binding|protein kinase binding|",10,1.2,10.1,10,0.4,3.89,0.7,12.4,12.4,0.169,0,0,0.3,1.8
ENSMUSG00000025178,PI4K2A,phosphatidylinositol 4-kinase type 2 alpha,cytoplasm|mitochondrion|lysosomal membrane|endosome|Golgi apparatus|plasma membrane|integral component of plasma membrane|membrane|membrane|cell junction|dendrite|synaptic vesicle membrane|BLOC-1 complex|cytoplasmic vesicle|early endosome membrane|growing cell tip|presynaptic membrane|cell projection|neuron projection|neuron projection|neuronal cell body|neuronal cell body|perikaryon|intracellular membrane-bounded organelle|protein complex|host cell presynaptic membrane|membrane raft|synapse|exocytic vesicle|,basophil degranulation|phosphatidylinositol biosynthetic process|phosphorylation|phosphatidylinositol phosphorylation|,"nucleotide binding|1-phosphatidylinositol 4-kinase activity|protein binding|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|protein complex binding|AP-3 adaptor complex binding|",10,-0.7,13.2,10,-0.3,1.5,-0.7,12.4,-12.4,0.169,0,0,-1.4,-0.3
ENSMUSG00000049928,GLP2R,glucagon-like peptide 2 receptor,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|cellular response to glucagon stimulus|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|glucagon receptor activity|,9,-1,2.84,9,0.9,15.3,0.8,12.3,12.3,0.169,0,0,0.4,1.9
ENSMUSG00000040867,BEGAIN,brain-enriched guanylate kinase-associated,cytoplasm|membrane|dendrite|neuronal cell body|,biological_process|,molecular_function|,10,-1.7,15.3,10,0,0,-1.7,12.1,-12.1,0.171,0,0,-3,-1.1
ENSMUSG00000057666,GAPDH,glyceraldehyde-3-phosphate dehydrogenase,nucleus|cytoplasm|cytoplasm|mitochondrion|lipid particle|cytosol|cytosol|plasma membrane|microtubule cytoskeleton|membrane|ribonucleoprotein complex|extracellular vesicular exosome|GAIT complex|,microtubule cytoskeleton organization|carbohydrate metabolic process|gluconeogenesis|glycolytic process|apoptotic process|multicellular organismal development|negative regulation of translation|peptidyl-cysteine S-trans-nitrosylation|protein stabilization|neuron apoptotic process|oxidation-reduction process|response to ammonium ion|cellular response to interferon-gamma|,glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity|glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity|microtubule binding|peptidyl-cysteine S-nitrosylase activity|identical protein binding|,4,1.1,13.3,4,0.2,0.271,1,11.8,11.8,0.174,0,0,0.6,2
ENSMUSG00000022965,IFNGR2,interferon gamma receptor 2,endoplasmic reticulum|plasma membrane|,None,None,10,0,0,10,0.5,12.9,0.5,11.5,11.5,0.177,0,0,0.2,1.5
ENSMUSG00000067798,MAGI2,"membrane associated guanylate kinase, WW and PDZ domain containing 2",nucleus|cytoplasm|cytoplasm|endosome|late endosome|plasma membrane|plasma membrane|tight junction|postsynaptic density|membrane|cell junction|dendrite|slit diaphragm|neuron projection|protein complex|synapse|perinuclear region of cytoplasm|,positive regulation of receptor internalization|signal transduction|nervous system development|negative regulation of cell proliferation|positive regulation of neuron projection development|cytoplasmic transport|negative regulation of cell migration|positive regulation of phosphoprotein phosphatase activity|negative regulation of activin receptor signaling pathway|nerve growth factor signaling pathway|receptor clustering|protein heterooligomerization|negative regulation of protein kinase B signaling|SMAD protein signal transduction|mitotic cell cycle arrest|cellular response to nerve growth factor stimulus|,signal transducer activity|protein binding|phosphatase binding|receptor signaling complex scaffold activity|receptor signaling complex scaffold activity|PDZ domain binding|beta-1 adrenergic receptor binding|protein complex binding|SMAD binding|type II activin receptor binding|,10,0.4,1.78,9,-0.6,13.7,-0.5,11.3,-11.3,0.178,0,0,-1.4,-0.2
ENSMUSG00000024038,NDUFV3,NADH dehydrogenase (ubiquinone) flavoprotein 3,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,poly(A) RNA binding|,10,-0.6,7.05,10,-0.4,5.46,-0.5,11.3,-11.3,0.178,0,0,-1,-0.2
ENSMUSG00000021816,PPP3CB,"protein phosphatase 3, catalytic subunit, beta isoform",plasma membrane|plasma membrane|calcineurin complex|protein complex|,negative regulation of T cell mediated cytotoxicity|protein phosphorylation|protein dephosphorylation|protein dephosphorylation|response to stress|heart development|regulation of gene expression|dephosphorylation|calcium ion-dependent exocytosis|T cell differentiation|locomotion involved in locomotory behavior|response to cytokine|cellular response to drug|positive regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of insulin secretion involved in cellular response to glucose stimulus|T cell homeostasis|regulation of insulin secretion|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|calcium-dependent protein serine/threonine phosphatase activity|calcium ion binding|protein binding|calmodulin binding|drug binding|hydrolase activity|enzyme binding|protein phosphatase 2B binding|calmodulin-dependent protein phosphatase activity|metal ion binding|protein heterodimerization activity|protein dimerization activity|,10,-1.3,14.6,10,0.5,4.17,-1.3,11.3,-11.3,0.178,0,0,-2,-0.3
ENSMUSG00000065990,AURKAIP1,aurora kinase A interacting protein 1,nucleus|nucleus|mitochondrion|mitochondrion|intracellular membrane-bounded organelle|,phosphorylation|positive regulation of proteolysis|,molecular_function|kinase activity|transferase activity|,10,-0.2,0.416,10,-1.1,12.8,-1.1,11.1,-11.1,0.18,0,0,-1.9,-0.6
ENSMUSG00000033009,OGFOD1,2-oxoglutarate and iron-dependent oxygenase domain containing 1,nucleus|cytoplasm|cytoplasmic stress granule|,regulation of translational termination|cell proliferation|protein hydroxylation|peptidyl-proline hydroxylation|stress granule assembly|oxidation-reduction process|,"sulfonate dioxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|L-ascorbic acid binding|peptidyl-proline dioxygenase activity|peptidyl-proline 3-dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.7,3.72,10,-0.8,9.55,-0.8,11.1,-11.1,0.18,0,0,-1.7,-0.3
ENSMUSG00000051331,CACNA1C,"calcium channel, voltage-dependent, L type, alpha 1C subunit",caveolar macromolecular signaling complex|cell|cytoplasm|plasma membrane|plasma membrane|voltage-gated calcium channel complex|voltage-gated calcium channel complex|postsynaptic density|membrane|membrane|integral component of membrane|Z disc|Z disc|Z disc|T-tubule|T-tubule|dendrite|sarcolemma|neuronal cell body|neuronal cell body|dendritic shaft|protein complex|,transport|ion transport|calcium ion transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|smooth muscle contraction|positive regulation of cytosolic calcium ion concentration|synaptic transmission|adult walking behavior|regulation of blood pressure|visual learning|calcium ion-dependent exocytosis|regulation of vasoconstriction|insulin secretion|growth hormone secretion|regulation of ion transmembrane transport|glucose homeostasis|regulation of organ growth|transmembrane transport|smooth muscle contraction involved in micturition|calcium ion import|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|calmodulin binding|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|enzyme binding|protein domain specific binding|ion channel binding|metal ion binding|alpha-actinin binding|protein phosphatase 2A binding|,10,-0.3,0.608,10,0.6,11.1,0.6,11,11,0.182,0,0,0.2,1.4
ENSMUSG00000026563,TADA1,transcriptional adaptor 1,nucleus|cytoplasm|focal adhesion|STAGA complex|SAGA-type complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|histone H3 acetylation|regulation of RNA biosynthetic process|",transcription coactivator activity|histone acetyltransferase activity|,6,1,10.6,7,-0.8,13.1,-0.8,10.8,-10.8,0.183,0,0,-2,1.3
ENSMUSG00000036095,DGKB,"diacylglycerol kinase, beta",cytoplasm|plasma membrane|membrane|,protein kinase C-activating G-protein coupled receptor signaling pathway|metabolic process|phosphorylation|intracellular signal transduction|,nucleotide binding|NAD+ kinase activity|diacylglycerol kinase activity|diacylglycerol kinase activity|calcium ion binding|ATP binding|kinase activity|transferase activity|metal ion binding|,10,-0.7,4.71,10,-0.8,6.58,-0.8,10.8,-10.8,0.183,0,0,-1.5,-0.2
ENSMUSG00000025270,ALAS2,"aminolevulinic acid synthase 2, erythroid",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|,response to hypoxia|porphyrin-containing compound metabolic process|heme biosynthetic process|cellular iron ion homeostasis|metabolic process|biosynthetic process|erythrocyte differentiation|tetrapyrrole biosynthetic process|hemoglobin biosynthetic process|,"catalytic activity|5-aminolevulinate synthase activity|5-aminolevulinate synthase activity|glycine binding|transferase activity|transferase activity, transferring acyl groups|pyridoxal phosphate binding|coenzyme binding|",10,-0.1,0.223,10,0.6,12.2,0.5,10.6,10.6,0.185,0,0,0.2,1.5
ENSMUSG00000002297,DBF4,DBF4 homolog (S. cerevisiae),nucleus|,DNA replication|protein phosphorylation|cell cycle|traversing start control point of mitotic cell cycle|,nucleic acid binding|protein serine/threonine kinase activity|zinc ion binding|metal ion binding|,10,-0.4,3.91,10,-1.2,8.4,-1.2,10.1,-10.1,0.191,0,0,-2,-0.3
ENSMUSG00000021311,MTR,5-methyltetrahydrofolate-homocysteine methyltransferase,intracellular|cytoplasm|,protein methylation|methionine metabolic process|cellular amino acid biosynthetic process|methionine biosynthetic process|methionine biosynthetic process|methylation|pteridine-containing compound metabolic process|cellular metabolic process|tetrahydrofolate metabolic process|homocysteine metabolic process|,folic acid binding|methyltransferase activity|zinc ion binding|methionine synthase activity|methionine synthase activity|S-adenosylmethionine-homocysteine S-methyltransferase activity|amino acid binding|transferase activity|cobalamin binding|metal ion binding|,7,0.6,2.42,7,0.7,8.26,0.7,10.1,10.1,0.191,0,0,-0.9,2
ENSMUSG00000028413,B4GALT1,"UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1",Golgi trans cisterna|extracellular region|extracellular space|Golgi apparatus|Golgi apparatus|plasma membrane|external side of plasma membrane|cell surface|cell surface|membrane|membrane|integral component of membrane|basolateral plasma membrane|desmosome|glycocalyx|brush border membrane|extracellular vesicular exosome|,epithelial cell development|acute inflammatory response|carbohydrate metabolic process|lactose biosynthetic process|galactose metabolic process|protein glycosylation|protein N-linked glycosylation|cell adhesion|binding of sperm to zona pellucida|binding of sperm to zona pellucida|penetration of zona pellucida|negative regulation of cell proliferation|negative regulation of cell proliferation|glycoprotein biosynthetic process|oligosaccharide biosynthetic process|oligosaccharide biosynthetic process|extracellular matrix organization|mammary gland development|wound healing|regulation of cell proliferation|positive regulation of apoptotic process|development of secondary sexual characteristics|branching morphogenesis of an epithelial tube|leukocyte migration|regulation of cellular component movement|regulation of acrosome reaction|positive regulation of epithelial cell proliferation involved in wound healing|angiogenesis involved in wound healing|positive regulation of apoptotic process involved in mammary gland involution|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity|beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity|beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity|N-acetyllactosamine synthase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|lactose synthase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|protein binding|cytoskeletal protein binding|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|manganese ion binding|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|UDP-galactosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|protein homodimerization activity|alpha-tubulin binding|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|beta-tubulin binding|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.7,3.35,10,0.5,7.31,0.5,10,10,0.192,0,0,0.2,1.1
ENSMUSG00000054342,KCNN4,"potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|neuronal cell body|neuronal cell body|membrane raft|,immune system process|transport|ion transport|potassium ion transport|calcium ion transport|anion transport|cell volume homeostasis|stabilization of membrane potential|phospholipid translocation|saliva secretion|positive regulation of protein secretion|positive regulation of T cell receptor signaling pathway|potassium ion export|potassium ion transmembrane transport|,potassium channel activity|calmodulin binding|calcium-activated potassium channel activity|calcium-activated potassium channel activity|small conductance calcium-activated potassium channel activity|protein phosphatase binding|Intermediate conductance calcium-activated potassium channel activity|Intermediate conductance calcium-activated potassium channel activity|,10,0.2,0.718,10,-1.2,10.9,-1.2,10,-10,0.192,0,0,-2,-0.5
ENSMUSG00000030785,COX6A2,cytochrome c oxidase subunit VIa polypeptide 2,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex IV|membrane|,None,cytochrome-c oxidase activity|,9,-1.4,13.1,9,0,0,-1.3,9.87,-9.87,0.193,0,0,-2,-0.6
ENSMUSG00000027010,SLC25A12,"solute carrier family 25 (mitochondrial carrier, Aralar), member 12",mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|membrane|integral component of membrane|,transport|aspartate transport|L-glutamate transport|malate-aspartate shuttle|malate-aspartate shuttle|response to calcium ion|transmembrane transport|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|calcium ion binding|L-aspartate transmembrane transporter activity|metal ion binding|,10,-0.7,0.429,10,-0.4,9.59,-0.4,9.73,-9.73,0.195,0,0,-1.1,-0.2
ENSMUSG00000020122,EGFR,epidermal growth factor receptor,intracellular|nucleus|nucleus|cytoplasm|endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|endocytic vesicle|endocytic vesicle|receptor complex|membrane raft|perinuclear region of cytoplasm|,"activation of MAPKK activity|cell morphogenesis|embryonic placenta development|positive regulation of protein phosphorylation|hair follicle development|translation|protein phosphorylation|signal transduction|signal transduction|cell surface receptor signaling pathway|transmembrane receptor protein tyrosine kinase signaling pathway|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|multicellular organismal development|salivary gland morphogenesis|learning or memory|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|epidermis development|magnesium ion homeostasis|phosphorylation|single organismal cell-cell adhesion|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cerebral cortex cell migration|positive regulation of cell migration|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|positive regulation of superoxide anion generation|positive regulation of catenin import into nucleus|intracellular signal transduction|regulation of cell proliferation|negative regulation of protein catabolic process|positive regulation of phosphorylation|ovulation cycle|negative regulation of apoptotic process|positive regulation of MAP kinase activity|positive regulation of nitric oxide biosynthetic process|positive regulation of DNA repair|positive regulation of DNA replication|positive regulation of vasoconstriction|positive regulation of vasodilation|negative regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|protein autophosphorylation|astrocyte activation|positive regulation of fibroblast proliferation|digestive tract morphogenesis|positive regulation of smooth muscle cell proliferation|neuron projection morphogenesis|positive regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|positive regulation of inflammatory response|regulation of peptidyl-tyrosine phosphorylation|regulation of peptidyl-tyrosine phosphorylation|regulation of nitric-oxide synthase activity|response to calcium ion|positive regulation of protein kinase B signaling|positive regulation of synaptic transmission, glutamatergic|morphogenesis of an epithelial fold|response to UV-A|positive regulation of ERK1 and ERK2 cascade|cellular response to amino acid stimulus|cellular response to epidermal growth factor stimulus|cellular response to estradiol stimulus|","nucleotide binding|glycoprotein binding|chromatin binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity|signal transducer activity|transmembrane signaling receptor activity|epidermal growth factor-activated receptor activity|epidermal growth factor-activated receptor activity|receptor binding|integrin binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|protein kinase binding|protein phosphatase binding|nitric-oxide synthase regulator activity|identical protein binding|protein heterodimerization activity|epidermal growth factor binding|actin filament binding|",10,0.9,11.8,10,-0.3,5.69,0.9,9.58,9.58,0.197,0,0,-0.3,2
ENSMUSG00000020990,CDKL1,cyclin-dependent kinase-like 1 (CDC2-related kinase),nucleus|cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,2.11,10,-0.7,10.5,-0.6,9.4,-9.4,0.2,0,0,-1.6,-0.2
ENSMUSG00000023938,AARS2,"alanyl-tRNA synthetase 2, mitochondrial (putative)",cytoplasm|mitochondrion|mitochondrion|,translation|alanyl-tRNA aminoacylation|mitochondrial respiratory chain complex assembly|tRNA aminoacylation|mitochondrial alanyl-tRNA aminoacylation|,"tRNA binding|nucleotide binding|nucleic acid binding|RNA binding|aminoacyl-tRNA ligase activity|alanine-tRNA ligase activity|ATP binding|ligase activity|ligase activity, forming aminoacyl-tRNA and related compounds|metal ion binding|",8,-0.6,9.13,9,0.5,4.06,-0.6,9.32,-9.32,0.201,0,0,-2,-0.2
ENSMUSG00000052234,EPX,eosinophil peroxidase,None,defense response to nematode|response to oxidative stress|negative regulation of interleukin-10 production|negative regulation of interleukin-5 production|positive regulation of interleukin-4 production|hydrogen peroxide catabolic process|oxidation-reduction process|eosinophil migration|,peroxidase activity|oxidoreductase activity|heme binding|metal ion binding|,10,-1.2,12.6,10,0,0,-1.2,9.29,-9.29,0.201,0,0,-2,-0.4
ENSMUSG00000041798,GCK,glucokinase,nucleus|nucleus|nucleoplasm|cytoplasm|mitochondrion|mitochondrion|cytosol|cytosol|cytosol|actin filament|cell cortex|secretory granule|basal cortex|,"cellular glucose homeostasis|cellular glucose homeostasis|carbohydrate metabolic process|glycogen biosynthetic process|fructose 2,6-bisphosphate metabolic process|glucose metabolic process|glucose metabolic process|glucose metabolic process|glycolytic process|glycolytic process|NADP metabolic process|positive regulation of cytosolic calcium ion concentration|phosphorylation|second-messenger-mediated signaling|positive regulation of insulin secretion|positive regulation of insulin secretion|negative regulation of epinephrine secretion|cellular response to insulin stimulus|cellular response to glucose starvation|positive regulation of phosphorylation|glucose homeostasis|glucose homeostasis|regulation of potassium ion transport|cellular response to leptin stimulus|negative regulation of gluconeogenesis|positive regulation of glycogen biosynthetic process|positive regulation of glycolytic process|carbohydrate phosphorylation|carbohydrate phosphorylation|carbohydrate phosphorylation|regulation of insulin secretion|regulation of insulin secretion|glucose 6-phosphate metabolic process|glucose 6-phosphate metabolic process|detection of glucose|lipid homeostasis|calcium ion import|","nucleotide binding|magnesium ion binding|glucokinase activity|glucokinase activity|glucokinase activity|hexokinase activity|protein binding|ATP binding|glucose binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|protein phosphatase binding|ADP binding|",10,0.7,2.01,9,0.9,7.74,0.8,9.25,9.25,0.202,0,0,0.2,1.7
ENSMUSG00000027254,MAP1A,microtubule-associated protein 1 A,cytoplasm|cytosol|cytoskeleton|microtubule|microtubule associated complex|,microtubule cytoskeleton organization|negative regulation of microtubule depolymerization|sensory perception of sound|,actin binding|protein binding|collagen binding|microtubule binding|,10,-0.2,0.234,10,-1.1,11.2,-1.1,9.06,-9.06,0.205,0,0,-2,-0.6
ENSMUSG00000015133,LRRK1,leucine-rich repeat kinase 1,intracellular|cytoplasm|mitochondrion|,protein phosphorylation|small GTPase mediated signal transduction|phosphorylation|osteoclast development|osteoclast development|bone resorption|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of peptidyl-tyrosine phosphorylation|positive regulation of intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|GTP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|metal ion binding|",10,-0.4,7.97,10,-0.2,1.73,-0.4,9.01,-9.01,0.205,0,0,-0.8,-0.1
ENSMUSG00000030397,MARK4,MAP/microtubule affinity-regulating kinase 4,centrosome|microtubule organizing center|microtubule cytoskeleton|neuron projection|,microtubule cytoskeleton organization|protein phosphorylation|nervous system development|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|microtubule binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|gamma-tubulin binding|tau-protein kinase activity|",10,-0.6,7.81,10,-0.3,1.93,-0.6,8.9,-8.9,0.207,0,0,-1.2,-0.2
ENSMUSG00000037112,SIK2,salt inducible kinase 2,intracellular|nucleus|cytoplasm|,protein phosphorylation|protein phosphorylation|insulin receptor signaling pathway|phosphorylation|intracellular signal transduction|intracellular signal transduction|regulation of insulin receptor signaling pathway|protein autophosphorylation|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.4,3.13,10,-0.4,6.1,-0.4,8.88,-8.88,0.207,0,0,-1.1,-0.2
ENSMUSG00000024941,SCYL1,SCY1-like 1 (S. cerevisiae),cytoplasm|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|cis-Golgi network|cytoskeleton|membrane|COPI vesicle coat|COPI vesicle coat|,"protein phosphorylation|transport|retrograde vesicle-mediated transport, Golgi to ER|vesicle-mediated transport|","protein kinase activity|protein binding|ATP binding|transferase activity, transferring phosphorus-containing groups|",9,-0.4,2.06,8,-0.8,7.9,-0.7,8.85,-8.85,0.208,0,0,-1.6,-0.2
ENSMUSG00000042282,GUCY2F,guanylate cyclase 2f,membrane|integral component of membrane|,cGMP biosynthetic process|protein phosphorylation|visual perception|cyclic nucleotide biosynthetic process|intracellular signal transduction|response to stimulus|,"nucleotide binding|guanylate cyclase activity|protein kinase activity|ATP binding|GTP binding|transferase activity, transferring phosphorus-containing groups|lyase activity|phosphorus-oxygen lyase activity|protein homodimerization activity|protein heterodimerization activity|",10,-0.2,0.289,10,-0.7,9.13,-0.7,8.83,-8.83,0.208,0,0,-1.5,-0.2
ENSMUSG00000007411,MARK3,MAP/microtubule affinity-regulating kinase 3,plasma membrane|membrane|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.5,6.14,10,-0.6,3.13,-0.5,8.83,-8.83,0.208,0,0,-1,-0.1
ENSMUSG00000027207,GALK2,galactokinase 2,cellular_component|cytoplasm|,galactose metabolic process|metabolic process|phosphorylation|carbohydrate phosphorylation|,"nucleotide binding|galactokinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|N-acetylgalactosamine kinase activity|",10,-0.5,1.29,10,-1.3,10.1,-1.3,8.81,-8.81,0.208,0,0,-2,-0.3
ENSMUSG00000038216,PNMT,phenylethanolamine-N-methyltransferase,cytoplasm|axon|dendrite|neuronal cell body|terminal bouton|varicosity|perikaryon|,methylation|norepinephrine metabolic process|epinephrine biosynthetic process|catecholamine biosynthetic process|,phenylethanolamine N-methyltransferase activity|methyltransferase activity|transferase activity|,10,-0.4,0.495,10,1,10.5,0.8,8.78,8.78,0.209,0,0,0.3,2
ENSMUSG00000027947,IL6RA,"interleukin 6 receptor, alpha",extracellular region|extracellular space|interleukin-6 receptor complex|cell surface|membrane|integral component of membrane|apical plasma membrane|neuronal cell body membrane|,positive regulation of cell proliferation|positive regulation of activation of Janus kinase activity|cell growth|cytokine-mediated signaling pathway|endocrine pancreas development|positive regulation of chemokine production|positive regulation of interleukin-6 production|negative regulation of collagen biosynthetic process|response to cytokine|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of MAPK cascade|positive regulation of JAK-STAT cascade|positive regulation of smooth muscle cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|interleukin-6-mediated signaling pathway|interleukin-6-mediated signaling pathway|ciliary neurotrophic factor-mediated signaling pathway|,cytokine receptor activity|ciliary neurotrophic factor receptor activity|interleukin-6 receptor activity|interleukin-6 receptor activity|interleukin-6 receptor activity|interleukin-6 receptor binding|enzyme binding|interleukin-6 binding|interleukin-6 binding|protein homodimerization activity|ciliary neurotrophic factor binding|,10,-0.4,1.81,10,0.9,11.1,0.6,8.74,8.74,0.21,0,0,0.2,1.9
ENSMUSG00000032215,RSL24D1,ribosomal L24 domain containing 1,cellular_component|nucleus|,biological_process|ribosome biogenesis|,molecular_function|,6,1.1,11.4,7,0,0,1,8.67,8.67,0.211,0,0,0.6,2
ENSMUSG00000025350,RDH5,retinol dehydrogenase 5,endoplasmic reticulum|endoplasmic reticulum lumen|membrane|cell body|,visual perception|metabolic process|response to stimulus|oxidation-reduction process|,oxidoreductase activity|,10,0.8,5.02,10,0.4,4.64,0.5,8.58,8.58,0.212,0,0,0.1,1.3
ENSMUSG00000027618,NFS1,nitrogen fixation gene 1 (S. cerevisiae),nucleus|nucleus|cytoplasm|mitochondrion|mitochondrial matrix|mitochondrial matrix|cytosol|,cysteine metabolic process|Mo-molybdopterin cofactor biosynthetic process|metabolic process|iron incorporation into metallo-sulfur cluster|iron incorporation into metallo-sulfur cluster|,catalytic activity|transferase activity|pyridoxal phosphate binding|cysteine desulfurase activity|protein homodimerization activity|,8,1.3,10.8,8,0.2,0.561,1.2,8.51,8.51,0.213,0,0,-2.5,2
ENSMUSG00000063849,PPCDC,phosphopantothenoylcysteine decarboxylase,cellular_component|,coenzyme A biosynthetic process|,catalytic activity|phosphopantothenoylcysteine decarboxylase activity|lyase activity|carboxy-lyase activity|,5,1.3,6.06,6,-0.8,7.41,-0.7,8.37,-8.37,0.216,0,0,-2,1.7
ENSMUSG00000062234,GAK,cyclin G associated kinase,cytoplasm|Golgi apparatus|membrane|cell junction|intracellular membrane-bounded organelle|,protein phosphorylation|endoplasmic reticulum organization|Golgi organization|cell cycle|epidermal cell differentiation|phosphorylation|intrahepatic bile duct development|cell development|forebrain morphogenesis|establishment of skin barrier|clathrin coat disassembly|clathrin-mediated endocytosis|positive regulation of neural precursor cell proliferation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|",6,-0.7,7.27,6,0.8,4.35,-0.6,8.28,-8.28,0.217,0,0,-2,0.6
ENSMUSG00000075318,SCN2A1,"sodium channel, voltage-gated, type II, alpha 1",voltage-gated sodium channel complex|voltage-gated sodium channel complex|intracellular|intercalated disc|membrane|integral component of membrane|T-tubule|axon|intrinsic component of plasma membrane|node of Ranvier|paranode region of axon|sodium channel complex|neuron projection|axon initial segment|,transport|ion transport|potassium ion transport|sodium ion transport|sodium ion transport|nervous system development|intrinsic apoptotic signaling pathway in response to osmotic stress|neuronal action potential|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|neuron apoptotic process|potassium ion transmembrane transport|membrane depolarization during action potential|,voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|potassium channel activity|sodium channel activity|sodium ion binding|leucine zipper domain binding|,10,1.3,11.2,10,0.1,0.203,1.3,8.2,8.2,0.219,0,0,0.5,3
ENSMUSG00000028431,IKBKAP,"inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein","nucleus|nucleolus|cytoplasm|transcription elongation factor complex|DNA-directed RNA polymerase II, holoenzyme|Elongator holoenzyme complex|","transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription elongation from RNA polymerase II promoter|I-kappaB phosphorylation|positive regulation of cell migration|regulation of protein kinase activity|",DNA binding|protein kinase activity|ATP binding|phosphorylase kinase regulator activity|,9,0.6,3.66,9,0.4,5.35,0.5,8.1,8.1,0.221,0,0,0.1,1.1
ENSMUSG00000020722,CACNG1,"calcium channel, voltage-dependent, gamma subunit 1",intracellular|cell|voltage-gated calcium channel complex|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|sarcoplasmic reticulum calcium ion transport|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|,10,0.7,2.66,10,0.9,5.94,0.8,8.08,8.08,0.221,0,0,0.2,1.7
ENSMUSG00000028961,PGD,phosphogluconate dehydrogenase,nucleus|cytoplasm|extracellular vesicular exosome|,"pentose-phosphate shunt|pentose-phosphate shunt, oxidative branch|pentose biosynthetic process|D-gluconate metabolic process|oxidation-reduction process|oxidation-reduction process|","phosphogluconate dehydrogenase (decarboxylating) activity|phosphogluconate dehydrogenase (decarboxylating) activity|phosphogluconate 2-dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|NADP binding|coenzyme binding|",5,0.5,4.52,3,0.6,3.91,0.6,8.05,8.05,0.222,0,0,0.2,1.7
ENSMUSG00000037916,NDUFV1,NADH dehydrogenase (ubiquinone) flavoprotein 1,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain|,transport|oxidation-reduction process|,"NADH dehydrogenase activity|protein binding|NADH dehydrogenase (ubiquinone) activity|FMN binding|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H|metal ion binding|NAD binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",8,-1,10.9,9,0.2,0.703,-0.9,8.04,-8.04,0.222,0,0,-2,0.6
ENSMUSG00000004815,DGKQ,"diacylglycerol kinase, theta",nucleus|cytoplasm|cytosol|cytoskeleton|plasma membrane|membrane|nuclear speck|,regulation of transcription from RNA polymerase II promoter|signal transduction|G-protein coupled receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|metabolic process|phosphorylation|cAMP-mediated signaling|response to ATP|intracellular signal transduction|thrombin receptor signaling pathway|protein kinase C signaling|,nucleotide binding|NAD+ kinase activity|diacylglycerol kinase activity|ATP binding|kinase activity|transferase activity|kinase binding|activating transcription factor binding|phospholipase binding|metal ion binding|,10,-0.4,4.08,10,-0.4,4.19,-0.4,7.92,-7.92,0.224,0,0,-0.9,-0.1
ENSMUSG00000021276,CINP,cyclin-dependent kinase 2 interacting protein,cellular_component|nucleus|,DNA replication|DNA repair|cellular response to DNA damage stimulus|cell cycle|biological_process|cell division|,molecular_function|,6,-0.7,2.76,7,0.6,8.13,0.5,7.91,7.91,0.224,0,0,-0.6,2
ENSMUSG00000001380,HARS,histidyl-tRNA synthetase,cytoplasm|,translation|tRNA aminoacylation for protein translation|histidyl-tRNA aminoacylation|biological_process|,nucleotide binding|molecular_function|aminoacyl-tRNA ligase activity|histidine-tRNA ligase activity|ATP binding|ligase activity|,8,1.3,10.6,6,-0.2,0.893,1.2,7.88,7.88,0.225,0,0,0.5,2
ENSMUSG00000024030,ABCG1,"ATP-binding cassette, sub-family G (WHITE), member 1",mitochondrion|endosome|Golgi apparatus|plasma membrane|external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|recycling endosome|,"ATP catabolic process|regulation of transcription, DNA-templated|transport|lipid transport|cholesterol metabolic process|response to organic substance|negative regulation of macrophage derived foam cell differentiation|regulation of cholesterol esterification|positive regulation of cholesterol efflux|negative regulation of lipid storage|cholesterol transport|intracellular cholesterol transport|cholesterol efflux|cholesterol efflux|phospholipid efflux|response to lipid|low-density lipoprotein particle remodeling|high-density lipoprotein particle remodeling|glycoprotein transport|cholesterol homeostasis|amyloid precursor protein catabolic process|reverse cholesterol transport|positive regulation of cholesterol biosynthetic process|transmembrane transport|phospholipid homeostasis|response to high density lipoprotein particle|toxin transport|",nucleotide binding|ATP binding|phospholipid transporter activity|ATPase activity|cholesterol transporter activity|toxin transporter activity|sterol-transporting ATPase activity|glycoprotein transporter activity|protein homodimerization activity|ADP binding|protein heterodimerization activity|,10,-1.2,7.72,10,-0.4,2,-0.7,7.8,-7.8,0.226,0,0,-2,-0.2
ENSMUSG00000000168,DLAT,dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex),mitochondrion|mitochondrion|mitochondrial pyruvate dehydrogenase complex|pyruvate dehydrogenase complex|pyruvate dehydrogenase complex|,carbohydrate metabolic process|glucose metabolic process|acetyl-CoA biosynthetic process from pyruvate|acetyl-CoA biosynthetic process from pyruvate|pyruvate metabolic process|tricarboxylic acid cycle|metabolic process|,"dihydrolipoyllysine-residue acetyltransferase activity|dihydrolipoyllysine-residue acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",9,-0.4,1.83,8,-0.4,6.28,-0.4,7.8,-7.8,0.226,0,0,-1.1,-0.1
ENSMUSG00000025017,PIK3AP1,phosphoinositide-3-kinase adaptor protein 1,cytoplasm|cytosol|plasma membrane|membrane|,positive regulation of phosphatidylinositol 3-kinase signaling|negative regulation of toll-like receptor signaling pathway|positive regulation of toll-like receptor signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway|toll-like receptor 7 signaling pathway|toll-like receptor 9 signaling pathway|regulation of inflammatory response|,protein binding|phosphatidylinositol 3-kinase regulatory subunit binding|identical protein binding|,9,0.4,1.79,10,0.4,6.22,0.4,7.7,7.7,0.228,0,0,0.1,1
ENSMUSG00000010803,GABRA1,"gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,"transport|ion transport|chloride transport|gamma-aminobutyric acid signaling pathway|synaptic transmission, GABAergic|cellular response to histamine|",GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|chloride channel activity|protein binding|drug binding|GABA receptor activity|,9,-0.7,9.14,9,-0.1,0.198,-0.6,7.68,-7.68,0.229,0,0,-1.5,-0.2
ENSMUSG00000026275,PPP1R7,"protein phosphatase 1, regulatory (inhibitor) subunit 7",nucleus|chromosome|extracellular vesicular exosome|,chromosome segregation|positive regulation of protein dephosphorylation|,None,6,-0.6,0.356,6,-0.9,7.96,-0.9,7.59,-7.59,0.231,0,0,-2,0.7
ENSMUSG00000050675,GP1BA,"glycoprotein 1b, alpha polypeptide",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|anchored component of external side of plasma membrane|anchored component of external side of plasma membrane|,cell morphogenesis|cell adhesion|blood coagulation|blood coagulation|hemostasis|fibrinolysis|,None,10,0.9,9.33,10,-0.1,0.252,0.5,7.58,7.58,0.231,0,0,0.2,1.7
ENSMUSG00000063445,NMRAL1,NmrA-like family domain containing 1,nucleus|cytoplasm|,biological_process|,molecular_function|,10,-1.9,4.29,10,-0.5,7.36,-0.8,7.44,-7.44,0.234,0,0,-2.7,-0.2
ENSMUSG00000015357,CLPX,caseinolytic mitochondrial matrix peptidase chaperone subunit,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|endopeptidase Clp complex|mitochondrial endopeptidase Clp complex|mitochondrial nucleoid|,ATP catabolic process|ATP catabolic process|protein folding|positive regulation of peptidase activity|proteolysis involved in cellular protein catabolic process|,nucleotide binding|ATP-dependent peptidase activity|protein binding|ATP binding|peptidase activator activity|ATPase activity|ATPase activity|metal ion binding|unfolded protein binding|,10,-0.2,1.98,10,-1,9.14,-0.6,7.4,-7.4,0.235,0,0,-1.8,-0.3
ENSMUSG00000063704,MAPK15,mitogen-activated protein kinase 15,nucleus|,negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|positive regulation of protein phosphorylation|protein phosphorylation|negative regulation of DNA replication|phosphorylation|positive regulation of protein ubiquitination|response to estradiol|positive regulation of protein catabolic process|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.8,5.4,10,-0.7,2.39,-0.7,7.36,-7.36,0.235,0,0,-2,0.3
ENSMUSG00000019849,PREP,prolyl endopeptidase,nucleus|cytoplasm|cytoplasm|cytosol|membrane|,proteolysis|proteolysis|protein metabolic process|,endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|peptide binding|serine-type exopeptidase activity|,9,0.4,1.97,9,0.8,6.25,0.5,7.21,7.21,0.238,0,0,0.1,1.7
ENSMUSG00000025190,GOT1,"glutamic-oxaloacetic transaminase 1, soluble",nucleus|cytoplasm|lysosome|cytosol|axon terminus|extracellular vesicular exosome|,oxaloacetate metabolic process|glycerol biosynthetic process|glycerol biosynthetic process|cellular amino acid metabolic process|aspartate metabolic process|aspartate biosynthetic process|aspartate catabolic process|cellular amino acid biosynthetic process|biosynthetic process|glutamate catabolic process to aspartate|glutamate catabolic process to 2-oxoglutarate|dicarboxylic acid metabolic process|fatty acid homeostasis|,catalytic activity|L-aspartate:2-oxoglutarate aminotransferase activity|L-aspartate:2-oxoglutarate aminotransferase activity|phosphatidylserine decarboxylase activity|transaminase activity|transferase activity|pyridoxal phosphate binding|carboxylic acid binding|L-cysteine:2-oxoglutarate aminotransferase activity|L-phenylalanine:2-oxoglutarate aminotransferase activity|,10,-0.4,4.24,10,0.9,10.4,0.8,7.18,7.18,0.239,0,0,-0.2,2
ENSMUSG00000045136,TUBB2B,"tubulin, beta 2B class IIB",nucleus|cytoplasm|cytoskeleton|microtubule|protein complex|,neuron migration|GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,-0.2,0.818,10,-0.5,7.65,-0.5,7.16,-7.16,0.24,0,0,-1.3,-0.1
ENSMUSG00000041506,RRP9,"RRP9, small subunit (SSU) processome component, homolog (yeast)",nucleus|ribonucleoprotein complex|,rRNA processing|biological_process|,RNA binding|poly(A) RNA binding|,9,-0.6,9.22,8,0.2,0.482,-0.6,7.11,-7.11,0.241,0,0,-2,1.2
ENSMUSG00000003228,GRK5,G protein-coupled receptor kinase 5,nucleus|cytoplasm|plasma membrane|membrane|,desensitization of G-protein coupled receptor protein signaling pathway|protein phosphorylation|apoptotic process|signal transduction|tachykinin receptor signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|Wnt signaling pathway|phosphorylation|termination of G-protein coupled receptor signaling pathway|negative regulation of apoptotic process|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|G-protein coupled receptor kinase activity|ATP binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,-0.3,3.07,9,-0.9,6.5,-0.5,7.11,-7.11,0.241,0,0,-2,0.7
ENSMUSG00000029245,EPHA5,Eph receptor A5,rough endoplasmic reticulum|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|dendrite|cell projection|neuronal cell body|perinuclear region of cytoplasm|,protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|axon guidance|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|peptidyl-tyrosine phosphorylation|cAMP-mediated signaling|hippocampus development|regulation of Rac GTPase activity|positive regulation of CREB transcription factor activity|regulation of actin cytoskeleton organization|ephrin receptor signaling pathway|ephrin receptor signaling pathway|negative regulation of synapse assembly|dendritic spine morphogenesis|regulation of insulin secretion involved in cellular response to glucose stimulus|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|GPI-linked ephrin receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor receptor binding|",10,-1,3.36,10,-0.6,4.75,-0.6,7.11,-7.11,0.241,0,0,-1.7,-0.1
ENSMUSG00000054115,SKP2,S-phase kinase-associated protein 2 (p45),nucleus|nucleolus|cytoplasm|aggresome|SCF ubiquitin ligase complex|SCF ubiquitin ligase complex|,G1/S transition of mitotic cell cycle|G2/M transition of mitotic cell cycle|G2/M transition of mitotic cell cycle|protein polyubiquitination|ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|phosphorylation|positive regulation of intracellular estrogen receptor signaling pathway|positive regulation of smooth muscle cell proliferation|regulation of cell cycle|,ubiquitin-protein transferase activity|protein binding|kinase activity|transferase activity|identical protein binding|,10,-0.1,0.183,10,0.9,10.1,0.9,7.04,7.04,0.243,0,0,0.2,1.9
ENSMUSG00000059981,TAOK2,TAO kinase 2,nucleus|nucleolus|cytoplasm|cytoskeleton|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|cell projection|receptor complex|,MAPK cascade|activation of MAPKK activity|activation of MAPKK activity|protein phosphorylation|response to stress|cellular response to DNA damage stimulus|regulation of cell shape|phosphorylation|actin cytoskeleton organization|G2 DNA damage checkpoint|positive regulation of stress-activated MAPK cascade|positive regulation of JNK cascade|focal adhesion assembly|stress-activated MAPK cascade|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase binding|",10,-0.5,2.24,10,-0.5,5.04,-0.5,6.97,-6.97,0.244,0,0,-1.4,-0.1
ENSMUSG00000024164,C3,complement component 3,extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,"positive regulation of type IIa hypersensitivity|positive regulation of protein phosphorylation|positive regulation of activation of membrane attack complex|immune system process|lipid metabolic process|fatty acid metabolic process|inflammatory response|complement activation|complement activation|complement activation, alternative pathway|complement activation, classical pathway|blood coagulation|positive regulation vascular endothelial growth factor production|positive regulation of glucose transport|regulation of triglyceride biosynthetic process|positive regulation of lipid storage|innate immune response|positive regulation of G-protein coupled receptor protein signaling pathway|positive regulation of angiogenesis|positive regulation of developmental growth|positive regulation of phagocytosis|positive regulation of ERK1 and ERK2 cascade|positive regulation of apoptotic cell clearance|",endopeptidase inhibitor activity|protein binding|lipid binding|C5L2 anaphylatoxin chemotactic receptor binding|cofactor binding|,9,0.6,4.73,9,-0.5,4.08,0.5,6.95,6.95,0.245,0,0,-0.6,1.6
ENSMUSG00000033862,CDK10,cyclin-dependent kinase 10,intracellular|nucleus|,protein phosphorylation|phosphorylation|positive regulation of MAPK cascade|regulation of cell cycle|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin-dependent protein kinase activity|",9,-0.8,3.71,10,-1.1,3.83,-1,6.81,-6.81,0.248,0,0,-1.9,-0.3
ENSMUSG00000009555,CDK9,cyclin-dependent kinase 9 (CDC2-related kinase),nucleus|nucleus|cytoplasm|positive transcription elongation factor complex b|positive transcription elongation factor complex b|positive transcription elongation factor complex b|membrane|PML body|intracellular membrane-bounded organelle|,"DNA repair|regulation of DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|cellular response to DNA damage stimulus|phosphorylation|regulation of histone modification|replication fork arrest|negative regulation of cell cycle arrest|cellular response to cytokine stimulus|","nucleotide binding|DNA binding|chromatin binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|snRNA binding|transcription regulatory region DNA binding|",2,-0.8,5.29,4,-0.6,2.2,-0.8,6.77,-6.77,0.249,0,0,-2,0.2
ENSMUSG00000025091,PNLIPRP2,pancreatic lipase-related protein 2,extracellular region|extracellular space|zymogen granule membrane|,lipid metabolic process|cellular defense response|digestion|phospholipid catabolic process|lipid catabolic process|galactolipid catabolic process|,catalytic activity|phospholipase activity|triglyceride lipase activity|calcium ion binding|lipase activity|hydrolase activity|metal ion binding|acylglycerol lipase activity|galactolipase activity|,10,-0.2,0.219,10,0.6,8.98,0.5,6.74,6.74,0.25,0,0,-0.3,1.9
ENSMUSG00000025393,ATP5B,"ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit","mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)|nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|plasma membrane|cell surface|membrane|mitochondrial membrane|proton-transporting two-sector ATPase complex, catalytic domain|mitochondrial nucleoid|proton-transporting ATP synthase complex, catalytic core F(1)|extracellular vesicular exosome|",angiogenesis|osteoblast differentiation|ADP biosynthetic process|ATP catabolic process|lipid metabolic process|ATP biosynthetic process|transport|ion transport|receptor-mediated endocytosis|negative regulation of cell adhesion involved in substrate-bound cell migration|ATP synthesis coupled proton transport|ATP hydrolysis coupled proton transport|proton transport|ATP metabolic process|regulation of intracellular pH|hydrogen ion transmembrane transport|,"nucleotide binding|calcium ion binding|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|ATPase activity|ATPase activity|lipoprotein particle receptor activity|MHC class I protein binding|proton-transporting ATP synthase activity, rotational mechanism|proton-transporting ATPase activity, rotational mechanism|",5,1.1,6.2,5,-0.5,6.93,0.9,6.73,6.73,0.25,0,0,-0.9,2
ENSMUSG00000009545,KCNQ1,"potassium voltage-gated channel, subfamily Q, member 1",lysosome|early endosome|late endosome|plasma membrane|integral component of plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|basolateral plasma membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle|sarcolemma|zymogen granule membrane|,regulation of gene expression by genetic imprinting|transport|ion transport|potassium ion transport|gene silencing|regulation of ion transmembrane transport|cellular response to drug|regulation of membrane potential|negative regulation of insulin secretion|transmembrane transport|cardiac muscle contraction|regulation of membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of atrial cardiac muscle cell membrane repolarization|positive regulation of gastric acid secretion|cellular response to cAMP|potassium ion export|potassium ion transmembrane transport|potassium ion transmembrane transport|response to anesthetic|cardiovascular system development|ventricular cardiac muscle cell action potential|membrane repolarization during action potential|membrane repolarization during cardiac muscle cell action potential|atrial cardiac muscle cell action potential|regulation of heart rate by cardiac conduction|positive regulation of potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|delayed rectifier potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|calmodulin binding|protein phosphatase 1 binding|outward rectifier potassium channel activity|protein kinase A catalytic subunit binding|protein kinase A regulatory subunit binding|protein homodimerization activity|ion channel binding|voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization|voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|scaffold protein binding|voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|,10,0,0,10,0.7,8.98,0.5,6.72,6.72,0.25,0,0,0.1,1.5
ENSMUSG00000062585,CNR2,cannabinoid receptor 2 (macrophage),plasma membrane|membrane|integral component of membrane|dendrite|extrinsic component of cytoplasmic side of plasma membrane|cell projection|neuron projection|neuronal cell body|,"inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|sensory perception of pain|negative regulation of synaptic transmission, GABAergic|response to lipopolysaccharide|negative regulation of mast cell activation|cannabinoid signaling pathway|negative regulation of action potential|negative regulation of inflammatory response|negative regulation of nitric-oxide synthase activity|",signal transducer activity|G-protein coupled receptor activity|cannabinoid receptor activity|,10,0.2,0.516,10,0.9,8.26,0.5,6.7,6.7,0.251,0,0,0.1,1.9
ENSMUSG00000074141,IL4I1,interleukin 4 induced 1,lysosome|,aromatic amino acid family metabolic process|oxidation-reduction process|,L-amino-acid oxidase activity|L-amino-acid oxidase activity|,10,-0.9,6.64,10,-0.4,1.44,-0.6,6.6,-6.6,0.254,0,0,-1.9,-0.1
ENSMUSG00000003617,CP,ceruloplasmin,extracellular region|extracellular space|extracellular space|lysosomal membrane|anchored component of plasma membrane|extracellular vesicular exosome|blood microparticle|,transport|ion transport|copper ion transport|cellular iron ion homeostasis|response to copper ion|oxidation-reduction process|,ferroxidase activity|copper ion binding|copper ion binding|oxidoreductase activity|metal ion binding|chaperone binding|,10,-0.4,1.89,10,-0.6,5.8,-0.5,6.56,-6.56,0.255,0,0,-1.3,-0.1
ENSMUSG00000044573,ACP1,"acid phosphatase 1, soluble",cytoplasm|cytoplasmic side of plasma membrane|extracellular vesicular exosome|,protein dephosphorylation|dephosphorylation|,acid phosphatase activity|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|non-membrane spanning protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,9,-0.5,6.31,9,0.8,8.47,0.5,6.55,6.55,0.255,0,0,-1.1,2
ENSMUSG00000038042,PTPDC1,protein tyrosine phosphatase domain containing 1,cellular_component|,protein dephosphorylation|smoothened signaling pathway|dephosphorylation|cell projection organization|cilium morphogenesis|,"molecular_function|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,-0.4,2.1,10,-0.5,4.85,-0.5,6.5,-6.5,0.256,0,0,-1.2,-0.1
ENSMUSG00000016493,CD46,"CD46 antigen, complement regulatory protein",acrosomal vesicle|inner acrosomal membrane|extracellular region|cytoplasm|Golgi apparatus|cell surface|membrane|integral component of membrane|basolateral plasma membrane|cytoplasmic vesicle|extracellular vesicular exosome|,T cell mediated immunity|proteolysis|single fertilization|regulation of Notch signaling pathway|positive regulation of gene expression|negative regulation of gene expression|interleukin-10 production|positive regulation of interleukin-10 production|sequestering of extracellular ligand from receptor|positive regulation of T cell proliferation|negative regulation of catalytic activity|positive regulation of memory T cell differentiation|positive regulation of regulatory T cell differentiation|negative regulation of complement activation|positive regulation of transforming growth factor beta production|,complement binding|endopeptidase activity|enzyme inhibitor activity|cadherin binding|,9,0.6,6.08,9,0.3,1.24,0.6,6.48,6.48,0.257,0,0,0.1,1.4
ENSMUSG00000031292,CDKL5,cyclin-dependent kinase-like 5,nucleus|cytoplasm|ruffle membrane|dendrite cytoplasm|dendritic growth cone|,neuron migration|protein phosphorylation|phosphorylation|positive regulation of Rac GTPase activity|positive regulation of axon extension|protein autophosphorylation|regulation of dendrite development|positive regulation of dendrite morphogenesis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rac GTPase binding|",10,-1.2,9.72,10,0.2,0.482,-1.1,6.42,-6.42,0.258,0,0,-2,-0.4
ENSMUSG00000021363,MAK,male germ cell-associated kinase,photoreceptor outer segment|photoreceptor inner segment|nucleus|cytoplasm|centrosome|cytoskeleton|cilium|midbody|cell projection|mitotic spindle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|phosphorylation|photoreceptor cell maintenance|protein autophosphorylation|regulation of RNA biosynthetic process|","nucleotide binding|transcription coactivator activity|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.9,8.43,0.5,6.37,6.37,0.26,0,0,0.1,1.9
ENSMUSG00000027774,GFM1,"G elongation factor, mitochondrial 1",intracellular|mitochondrion|mitochondrion|,GTP catabolic process|translation|translational elongation|mitochondrial translational elongation|,nucleotide binding|translation elongation factor activity|GTPase activity|GTP binding|poly(A) RNA binding|,8,-1,7.65,9,0.5,3.3,-0.6,6.36,-6.36,0.26,0,0,-2,0.9
ENSMUSG00000029513,PRKAB1,"protein kinase, AMP-activated, beta 1 non-catalytic subunit",nucleus|AMP-activated protein kinase complex|protein complex|,protein phosphorylation|protein phosphorylation|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|positive regulation of gene expression|phosphorylation|regulation of catalytic activity|protein heterooligomerization|,protein kinase activity|AMP-activated protein kinase activity|AMP-activated protein kinase activity|protein binding|kinase activity|transferase activity|protein kinase binding|,9,-0.5,8.07,9,0.4,2.15,-0.5,6.36,-6.36,0.26,0,0,-1.9,0
ENSMUSG00000030737,SLCO2B1,"solute carrier organic anion transporter family, member 2b1",plasma membrane|basal plasma membrane|membrane|integral component of membrane|apical plasma membrane|,transport|ion transport|lipid transport|organic anion transport|bile acid and bile salt transport|ion transmembrane transport|sodium-independent icosanoid transport|,transporter activity|organic anion transmembrane transporter activity|bile acid transmembrane transporter activity|sodium-independent organic anion transmembrane transporter activity|,10,0.8,0.342,10,0.8,6.17,0.8,6.3,6.3,0.261,0,0,0.1,1.9
ENSMUSG00000025127,GCGR,glucagon receptor,endosome|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,exocytosis|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|hormone-mediated signaling pathway|glucose homeostasis|response to starvation|regulation of glycogen metabolic process|cellular response to glucagon stimulus|cellular response to glucagon stimulus|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|glucagon receptor activity|glucagon receptor activity|peptide hormone binding|,10,0.1,0.257,10,0.6,6.73,0.5,6.23,6.23,0.263,0,0,0,1.3
ENSMUSG00000040086,TNNI3K,TNNI3 interacting kinase,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|troponin I binding|metal ion binding|",9,0.1,0.152,9,0.7,7.52,0.6,6.21,6.21,0.264,0,0,0.1,1.6
ENSMUSG00000069255,DUSP22,dual specificity phosphatase 22,cellular_component|nucleus|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|protein dephosphorylation|transforming growth factor beta receptor signaling pathway|dephosphorylation|regulation of cell proliferation|positive regulation of JNK cascade|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,1,4.86,10,0.4,2.61,0.8,6.17,6.17,0.265,0,0,0.2,1.8
ENSMUSG00000021748,PDHB,pyruvate dehydrogenase (lipoamide) beta,nucleus|mitochondrion|mitochondrion|pyruvate dehydrogenase complex|extracellular vesicular exosome|,carbohydrate metabolic process|glucose metabolic process|acetyl-CoA biosynthetic process from pyruvate|tricarboxylic acid cycle|metabolic process|oxidation-reduction process|,catalytic activity|pyruvate dehydrogenase activity|pyruvate dehydrogenase (acetyl-transferring) activity|oxidoreductase activity|,9,-0.6,8.02,9,0,0,-0.5,6.16,-6.16,0.265,0,0,-1.6,-0.1
ENSMUSG00000041245,WNK3,WNK lysine deficient protein kinase 3,cytoplasm|adherens junction|tight junction|,protein phosphorylation|positive regulation of sodium ion transport|positive regulation of peptidyl-threonine phosphorylation|phosphorylation|positive regulation of ion transmembrane transporter activity|negative regulation of apoptotic process|protein autophosphorylation|positive regulation of calcium ion transport|positive regulation of establishment of protein localization to plasma membrane|regulation of ion homeostasis|positive regulation of sodium ion transmembrane transporter activity|positive regulation of rubidium ion transport|positive regulation of rubidium ion transmembrane transporter activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|chloride channel inhibitor activity|",10,-1.3,9.19,10,-0.1,0.157,-1.2,6.1,-6.1,0.267,0,0,-2,-0.2
ENSMUSG00000021595,NSUN2,NOL1/NOP2/Sun domain family member 2,nucleus|nucleolus|cytoplasm|cytoskeleton|,cell cycle|mitotic nuclear division|tRNA processing|tRNA methylation|methylation|cell division|,tRNA binding|RNA binding|methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|transferase activity|poly(A) RNA binding|,10,0.7,4,10,0.4,2.6,0.4,5.94,5.94,0.272,0,0,0.1,1.5
ENSMUSG00000030671,PDE3B,"phosphodiesterase 3B, cGMP-inhibited",endoplasmic reticulum|Golgi apparatus|membrane|membrane|integral component of membrane|guanyl-nucleotide exchange factor complex|,angiogenesis|cAMP catabolic process|negative regulation of cell adhesion|signal transduction|negative regulation of angiogenesis|endocrine pancreas development|glucose homeostasis|negative regulation of insulin secretion|regulation of insulin secretion|negative regulation of lipid catabolic process|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|drug binding|hydrolase activity|cAMP binding|protein kinase B binding|metal ion binding|phosphoprotein binding|",10,1,3.11,10,0.8,3.48,0.9,5.9,5.9,0.273,0,0,-0.2,2
ENSMUSG00000026670,UAP1,UDP-N-acetylglucosamine pyrophosphorylase 1,cytoplasm|cytosol|,UDP-N-acetylglucosamine metabolic process|metabolic process|,UDP-N-acetylglucosamine diphosphorylase activity|transferase activity|nucleotidyltransferase activity|carbohydrate binding|uridylyltransferase activity|,10,0.2,1.12,10,-0.5,6.72,-0.5,5.89,-5.89,0.273,0,0,-1.3,0.5
ENSMUSG00000036529,SBF1,SET binding factor 1,cellular_component|nucleus|,regulation of cell growth|spermatogenesis|dephosphorylation|positive regulation of Rab GTPase activity|negative regulation of catalytic activity|,pseudophosphatase activity|guanyl-nucleotide exchange factor activity|phosphatase activity|Rab guanyl-nucleotide exchange factor activity|,10,0.7,8.37,10,0.1,0.156,0.7,5.86,5.86,0.274,0,0,0.1,1.5
ENSMUSG00000052459,ATP6V1A,"ATPase, H+ transporting, lysosomal V1 subunit A","mitochondrion|lysosomal membrane|cytosol|plasma membrane|microvillus|apical plasma membrane|proton-transporting two-sector ATPase complex, catalytic domain|proton-transporting V-type ATPase, V1 domain|extracellular vesicular exosome|",transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|ATP metabolic process|,"nucleotide binding|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|proton-transporting ATPase activity, rotational mechanism|",7,-0.8,5.64,7,0.3,0.905,-0.4,5.83,-5.83,0.275,0,0,-1.8,0.1
ENSMUSG00000017868,SGK2,serum/glucocorticoid regulated kinase 2,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|potassium channel regulator activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.3,0.796,10,0.6,5.52,0.4,5.76,5.76,0.277,0,0,0,1.3
ENSMUSG00000048490,NRIP1,nuclear receptor interacting protein 1,histone deacetylase complex|nucleus|nucleus|nuclear speck|cell junction|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|ovarian follicle rupture|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|lipid storage|ovulation|positive regulation of transcription from RNA polymerase II promoter|",transcription cofactor activity|transcription coactivator activity|transcription corepressor activity|transcription corepressor activity|receptor binding|protein binding|estrogen receptor binding|nuclear hormone receptor binding|glucocorticoid receptor binding|histone deacetylase binding|retinoic acid receptor binding|retinoid X receptor binding|,9,0.5,2.37,10,0.5,3.65,0.5,5.72,5.72,0.278,0,0,-0.3,1.4
ENSMUSG00000031506,PTPN7,"protein tyrosine phosphatase, non-receptor type 7",cytoplasm|cytosol|cytoskeleton|cytoplasmic side of plasma membrane|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,10,0.6,2.26,10,0.4,4.2,0.4,5.71,5.71,0.279,0,0,0,1.5
ENSMUSG00000054252,FGFR3,fibroblast growth factor receptor 3,nucleus|cytoplasm|lysosome|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|cytoplasmic side of plasma membrane|cell surface|membrane|integral component of membrane|cytoplasmic vesicle|perinuclear region of cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|skeletal system development|positive regulation of endothelial cell proliferation|morphogenesis of an epithelium|lens morphogenesis in camera-type eye|protein phosphorylation|apoptotic process|cell-cell signaling|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|positive regulation of phospholipase activity|oligodendrocyte development|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|substantia nigra development|central nervous system myelination|cell differentiation|bone mineralization|forebrain development|positive regulation of protein ubiquitination|somatic stem cell maintenance|post-anal tail morphogenesis|positive regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of MAPK cascade|positive regulation of MAPK cascade|positive regulation of neuron apoptotic process|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of cell differentiation|negative regulation of mitosis|negative regulation of smoothened signaling pathway|protein autophosphorylation|digestive tract morphogenesis|negative regulation of developmental growth|response to axon injury|negative regulation of astrocyte differentiation|inner ear development|negative regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|cartilage development|inner ear receptor cell differentiation|inner ear receptor cell differentiation|bone morphogenesis|axonogenesis involved in innervation|alveolar secondary septum development|lens fiber cell development|positive regulation of ERK1 and ERK2 cascade|bone maturation|epithelial cell fate commitment|positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway|cochlea development|positive regulation of canonical Wnt signaling pathway|fibroblast growth factor receptor apoptotic signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|fibroblast growth factor-activated receptor activity|fibroblast growth factor-activated receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|fibroblast growth factor binding|",10,-0.1,0.0795,10,0.9,8.49,0.6,5.68,5.68,0.28,0,0,-1.4,2
ENSMUSG00000026701,PRDX6,peroxiredoxin 6,extracellular space|cytoplasm|mitochondrion|lysosome|cytosol|membrane|cytoplasmic vesicle|extracellular vesicular exosome|,response to reactive oxygen species|lipid metabolic process|response to oxidative stress|metabolic process|phospholipid catabolic process|lipid catabolic process|bleb assembly|hydrogen peroxide catabolic process|oxidation-reduction process|,"catalytic activity|peroxidase activity|glutathione peroxidase activity|phospholipase activity|phospholipase A2 activity|prenylcysteine methylesterase activity|antioxidant activity|lipase activity|oxidoreductase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|peroxiredoxin activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",9,-0.9,2.27,9,-0.7,3.9,-0.7,5.66,-5.66,0.28,0,0,-1.8,-0.1
ENSMUSG00000024953,PRDX5,peroxiredoxin 5,extracellular space|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|peroxisome|peroxisomal matrix|peroxisomal matrix|cytosol|cytoplasmic vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|extracellular vesicular exosome|,response to oxidative stress|response to oxidative stress|negative regulation of transcription from RNA polymerase III promoter|positive regulation of collagen biosynthetic process|cellular response to reactive oxygen species|hydrogen peroxide catabolic process|hydrogen peroxide catabolic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of oxidoreductase activity|oxidation-reduction process|regulation of apoptosis involved in tissue homeostasis|NADPH oxidation|reactive nitrogen species metabolic process|regulation of RNA biosynthetic process|,RNA polymerase III regulatory region DNA binding|peroxidase activity|receptor binding|receptor binding|antioxidant activity|antioxidant activity|oxidoreductase activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|protein dimerization activity|peroxiredoxin activity|peroxynitrite reductase activity|,10,-0.2,0.487,10,0.5,8.02,0.5,5.61,5.61,0.282,0,0,-0.1,1.5
ENSMUSG00000054733,MSRA,methionine sulfoxide reductase A,nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|membrane|extracellular vesicular exosome|,response to oxidative stress|aging|protein repair|oxidation-reduction process|,"peptide-methionine (S)-S-oxide reductase activity|peptide-methionine (S)-S-oxide reductase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor|",9,0.6,2.26,10,0.8,3.84,0.6,5.58,5.58,0.283,0,0,-0.2,1.8
ENSMUSG00000028874,FGR,Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog,cytoplasm|mitochondrion|mitochondrial inner membrane|cytosol|cytoskeleton|plasma membrane|plasma membrane|actin cytoskeleton|membrane|ruffle membrane|cell projection|extracellular vesicular exosome|,immune system process|protein phosphorylation|integrin-mediated signaling pathway|integrin-mediated signaling pathway|regulation of cell shape|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of cell migration|regulation of actin cytoskeleton organization|positive regulation of mast cell degranulation|positive regulation of phosphatidylinositol 3-kinase activity|innate immune response|regulation of innate immune response|regulation of protein kinase activity|protein autophosphorylation|positive regulation of cytokine secretion|regulation of phagocytosis|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|,"nucleotide binding|phosphotyrosine binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein kinase binding|immunoglobulin receptor binding|Fc-gamma receptor I complex binding|",10,1.3,3.58,10,0.8,3.39,1.1,5.56,5.56,0.284,0,0,0.2,2
ENSMUSG00000053198,PRX,periaxin,nucleus|cytoplasm|plasma membrane|membrane|myelin sheath|,regulation of RNA splicing|,protein binding|,10,0,0,10,0.6,7.14,0.6,5.53,5.53,0.285,0,0,0.1,1.7
ENSMUSG00000050107,GSG2,germ cell-specific gene 2,nucleus|nucleus|chromosome|cytoplasm|centrosome|spindle|cytoskeleton|,"protein phosphorylation|protein phosphorylation|cell cycle|mitotic sister chromatid cohesion|phosphorylation|chromatin modification|intracellular signal transduction|intracellular signal transduction|protein localization to chromosome, centromeric region|regulation of spindle checkpoint|negative regulation of G1/S transition of mitotic cell cycle|histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore|","nucleotide binding|DNA binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|histone kinase activity (H3-T3 specific)|",10,0.3,3.28,10,0.3,2.52,0.3,5.5,5.5,0.286,0,0,-0.2,1.1
ENSMUSG00000026434,NUCKS1,nuclear casein kinase and cyclin-dependent kinase substrate 1,nucleus|nucleus|cytoplasm|,biological_process|,poly(A) RNA binding|,10,0,0,10,-0.8,8.32,-0.8,5.48,-5.48,0.286,0,0,-1.8,-0.1
ENSMUSG00000021876,RNASE4,"ribonuclease, RNase A family 4",extracellular region|extracellular vesicular exosome|,cellular response to starvation|,molecular_function|nucleic acid binding|nuclease activity|endonuclease activity|hydrolase activity|,10,-0.5,5.58,10,-0.2,0.832,-0.3,5.38,-5.38,0.29,0,0,-1.6,0
ENSMUSG00000038967,PDK2,"pyruvate dehydrogenase kinase, isoenzyme 2",mitochondrion|mitochondrion|mitochondrial pyruvate dehydrogenase complex|pyruvate dehydrogenase complex|,carbohydrate metabolic process|glucose metabolic process|regulation of gluconeogenesis|protein phosphorylation|protein phosphorylation|regulation of pH|insulin receptor signaling pathway|regulation of acetyl-CoA biosynthetic process from pyruvate|regulation of cellular ketone metabolic process|regulation of glucose metabolic process|phosphorylation|peptidyl-serine phosphorylation|cellular response to nutrient|cellular response to reactive oxygen species|glucose homeostasis|intrinsic apoptotic signaling pathway by p53 class mediator|,nucleotide binding|protein serine/threonine kinase activity|pyruvate dehydrogenase (acetyl-transferring) kinase activity|pyruvate dehydrogenase (acetyl-transferring) kinase activity|protein binding|ATP binding|kinase activity|transferase activity|protein complex binding|protein homodimerization activity|protein heterodimerization activity|,9,0.9,5.92,9,0.4,1.55,0.8,5.36,5.36,0.29,0,0,-1.4,2
ENSMUSG00000024680,MS4A2,"membrane-spanning 4-domains, subfamily A, member 2",endosome|integral component of plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|Fc-epsilon receptor I complex|membrane raft|membrane raft|,inflammatory response|immune response|signal transduction|signal transduction|cell surface receptor signaling pathway|activation of phospholipase C activity|protein kinase C-activating G-protein coupled receptor signaling pathway|Fc-epsilon receptor signaling pathway|positive regulation of mast cell degranulation|cytokine secretion|regulation of release of sequestered calcium ion into cytosol|,IgE receptor activity|IgE binding|protein kinase binding|SH2 domain binding|phosphoprotein binding|,10,0.9,8.23,9,-0.1,0.0602,0.9,5.32,5.32,0.292,0,0,0.1,2
ENSMUSG00000047714,PPP1R2,"protein phosphatase 1, regulatory (inhibitor) subunit 2",None,carbohydrate metabolic process|glycogen metabolic process|regulation of signal transduction|regulation of phosphoprotein phosphatase activity|,protein phosphatase inhibitor activity|,7,0.7,3.81,6,-0.5,4.33,0.7,5.31,5.31,0.292,0,0,-0.8,1.9
ENSMUSG00000030753,PRKRIR,"protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)",nucleus|,biological_process|phosphorylation|,nucleic acid binding|DNA binding|kinase activity|transferase activity|metal ion binding|protein dimerization activity|,9,0.8,6.51,9,0,0,0.7,5.28,5.28,0.293,0,0,-0.7,1.8
ENSMUSG00000059456,PTK2B,PTK2 protein tyrosine kinase 2 beta,nucleus|nucleus|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|cell cortex|postsynaptic density|membrane|N-methyl-D-aspartate selective glutamate receptor complex|lamellipodium|cell junction|axon|dendrite|growth cone|cell projection|neuronal cell body|cell body|membrane raft|perinuclear region of cytoplasm|apical dendrite|,"MAPK cascade|angiogenesis|oocyte maturation|positive regulation of cell-matrix adhesion|sprouting angiogenesis|marginal zone B cell differentiation|immune system process|protein phosphorylation|cellular defense response|actin filament organization|cell adhesion|cell surface receptor signaling pathway|signal complex assembly|epidermal growth factor receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|integrin-mediated signaling pathway|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|regulation of cell shape|regulation of cell shape|positive regulation of endothelial cell migration|positive regulation of endothelial cell migration|negative regulation of muscle cell apoptotic process|regulation of cGMP-mediated signaling|regulation of macrophage chemotaxis|positive regulation of neuron projection development|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|regulation of cell adhesion|negative regulation of ossification|positive regulation of cell growth|positive regulation of cell migration|negative regulation of bone mineralization|regulation of cGMP biosynthetic process|positive regulation of actin filament polymerization|neuron projection development|activation of Rac GTPase activity|regulation of inositol trisphosphate biosynthetic process|tumor necrosis factor-mediated signaling pathway|ionotropic glutamate receptor signaling pathway|peptidyl-tyrosine autophosphorylation|response to hydrogen peroxide|activation of Janus kinase activity|negative regulation of apoptotic process|negative regulation of apoptotic process|stress fiber assembly|negative regulation of potassium ion transport|positive regulation of JUN kinase activity|negative regulation of neuron apoptotic process|blood vessel endothelial cell migration|positive regulation of phosphatidylinositol 3-kinase activity|regulation of nitric oxide biosynthetic process|bone resorption|negative regulation of myeloid cell differentiation|positive regulation of translation|positive regulation of angiogenesis|positive regulation of protein kinase activity|positive regulation of protein kinase activity|positive regulation of JNK cascade|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|focal adhesion assembly|positive regulation of peptidyl-tyrosine phosphorylation|regulation of calcium-mediated signaling|positive regulation of nitric-oxide synthase activity|regulation of release of sequestered calcium ion into cytosol|positive regulation of synaptic transmission, glutamatergic|long-term synaptic potentiation|chemokine-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade|cellular response to retinoic acid|regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of establishment of cell polarity|regulation of actin cytoskeleton reorganization|regulation of N-methyl-D-aspartate selective glutamate receptor activity|positive regulation of reactive oxygen species metabolic process|positive regulation of excitatory postsynaptic membrane potential|positive regulation of B cell chemotaxis|","nucleotide binding|protein kinase activity|calmodulin-dependent protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|signal transducer activity|N-methyl-D-aspartate selective glutamate receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein complex binding|3-phosphoinositide-dependent protein kinase binding|",10,-0.2,0.921,10,-0.7,5.96,-0.5,5.25,-5.25,0.295,0,0,-1.7,0.3
ENSMUSG00000026842,ABL1,"c-abl oncogene 1, non-receptor tyrosine kinase",ruffle|nucleus|nucleus|nucleolus|cytoplasm|mitochondrion|cytosol|cytosol|cytoskeleton|actin cytoskeleton|cell leading edge|neuron projection|perinuclear region of cytoplasm|,"B-1 B cell homeostasis|B cell proliferation involved in immune response|B cell proliferation involved in immune response|transitional one stage B cell differentiation|DNA repair|protein phosphorylation|endocytosis|phagocytosis|autophagy|apoptotic process|cellular response to DNA damage stimulus|DNA damage induced protein phosphorylation|response to oxidative stress|response to oxidative stress|cell adhesion|epidermal growth factor receptor signaling pathway|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cerebellum morphogenesis|microspike assembly|actin cytoskeleton organization|negative regulation of BMP signaling pathway|regulation of actin cytoskeleton organization|positive regulation of osteoblast proliferation|substrate adhesion-dependent cell spreading|B cell proliferation|signal transduction in response to DNA damage|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of mitotic cell cycle|negative regulation of mitotic cell cycle|alpha-beta T cell differentiation|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|spleen development|thymus development|collateral sprouting|positive regulation of peptidyl-tyrosine phosphorylation|activated T cell proliferation|B cell receptor signaling pathway|neuromuscular process controlling balance|positive regulation of release of sequestered calcium ion into cytosol|positive regulation of oxidoreductase activity|negative regulation of ubiquitin-protein transferase activity|regulation of cell cycle|Bergmann glial cell differentiation|negative regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|cellular response to lipopolysaccharide|negative regulation of protein serine/threonine kinase activity|actin filament branching|positive regulation of interleukin-2 secretion|positive regulation of neuron death|positive regulation of interferon-gamma secretion|regulation of extracellular matrix organization|positive regulation of Wnt signaling pathway, planar cell polarity pathway|regulation of cellular senescence|negative regulation of cellular senescence|regulation of response to DNA damage stimulus|","nucleotide binding|magnesium ion binding|magnesium ion binding|DNA binding|protein kinase activity|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SH3 domain binding|protein domain specific binding|syntaxin binding|manganese ion binding|manganese ion binding|metal ion binding|actin filament binding|mitogen-activated protein kinase binding|proline-rich region binding|",10,0.4,3.75,10,0.3,1.82,0.3,5.23,5.23,0.295,0,0,-0.3,1
ENSMUSG00000021606,NDUFS6,NADH dehydrogenase (ubiquinone) Fe-S protein 6,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain|,fatty acid metabolic process|transport|muscle contraction|multicellular organismal aging|respiratory electron transport chain|multicellular organism growth|oxidation-reduction process|reproductive system development|mitochondrion morphogenesis|cardiovascular system development|,molecular_function|,10,-0.9,8.17,9,0,0,-0.8,5.22,-5.22,0.296,0,0,-2,-0.2
ENSMUSG00000039095,EN2,engrailed 2,nucleus|membrane|,"regulation of transcription, DNA-templated|multicellular organismal development|neuron differentiation|midbrain development|hindbrain development|positive regulation of transcription from RNA polymerase II promoter|neuron development|",DNA binding|sequence-specific DNA binding|,10,0,0,10,0.6,7.47,0.5,5.2,5.2,0.297,0,0,0.1,1.8
ENSMUSG00000032478,NME6,NME/NM23 nucleoside diphosphate kinase 6,mitochondrion|mitochondrion|,nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|nucleotide metabolic process|phosphorylation|negative regulation of cell growth|negative regulation of mitosis|,nucleotide binding|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|metal ion binding|,9,-0.8,4.85,9,-0.3,2.4,-0.5,5.16,-5.16,0.298,0,0,-1.6,0.1
ENSMUSG00000026853,CRAT,carnitine acetyltransferase,mitochondrion|mitochondrion|mitochondrial inner membrane|peroxisome|endoplasmic reticulum|membrane|,"lipid metabolic process|fatty acid metabolic process|transport|carnitine metabolic process, CoA-linked|","carnitine O-acetyltransferase activity|receptor binding|transferase activity|transferase activity, transferring acyl groups|",10,0.4,3.42,10,0.5,2.16,0.4,5.14,5.14,0.299,0,0,0,1.2
ENSMUSG00000038587,AKAP12,A kinase (PRKA) anchor protein (gravin) 12,cytoplasm|cytoskeleton|,protein targeting|signal transduction|signal transduction|positive regulation of protein kinase A signaling|phosphorylation|positive regulation of cAMP biosynthetic process|regulation of protein kinase C signaling|,adenylate cyclase binding|kinase activity|transferase activity|receptor signaling complex scaffold activity|protein kinase A binding|,10,-0.1,0.0711,9,-1.3,8.21,-1.2,5.11,-5.11,0.3,0,0,-2,-0.1
ENSMUSG00000013584,ALDH1A2,"aldehyde dehydrogenase family 1, subfamily A2",cytoplasm|cytosol|perinuclear region of cytoplasm|,retinoid metabolic process|blood vessel development|regulation of endothelial cell proliferation|heart looping|retinoic acid biosynthetic process|heart morphogenesis|heart development|metabolic process|positive regulation of cell proliferation|negative regulation of cell proliferation|determination of bilateral symmetry|anterior/posterior pattern specification|anterior/posterior pattern specification|proximal/distal pattern formation|positive regulation of gene expression|neural crest cell development|neural crest cell development|morphogenesis of embryonic epithelium|neural tube development|neuron differentiation|lung development|embryonic limb morphogenesis|forebrain development|hindbrain development|pancreas development|embryonic camera-type eye development|response to cytokine|embryonic forelimb morphogenesis|ureter maturation|retinoic acid metabolic process|retinoic acid metabolic process|retinoic acid metabolic process|retinal metabolic process|9-cis-retinoic acid biosynthetic process|camera-type eye development|positive regulation of apoptotic process|retinoic acid receptor signaling pathway|retinoic acid receptor signaling pathway|embryonic digestive tract development|cardiac muscle tissue development|oxidation-reduction process|face development|face development|,"retinal dehydrogenase activity|retinal dehydrogenase activity|3-chloroallyl aldehyde dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|retinal binding|",10,1,1.58,10,0.7,3.87,0.8,5.01,5.01,0.304,0,0,0.1,1.8
ENSMUSG00000019254,PPP1R12C,"protein phosphatase 1, regulatory (inhibitor) subunit 12C",cellular_component|cytoplasm|,biological_process|,molecular_function|,9,0.9,6.1,9,0.2,0.224,0.8,4.91,4.91,0.308,0,0,-0.1,2
ENSMUSG00000021996,ESD,esterase D/formylglutathione hydrolase,nucleus|cytoplasm|Golgi apparatus|plasma membrane|cytoplasmic vesicle|extracellular vesicular exosome|,formaldehyde catabolic process|,"hydrolase activity|hydrolase activity, acting on ester bonds|hydrolase activity, acting on ester bonds|S-formylglutathione hydrolase activity|",10,-0.5,4.62,10,-0.2,1.31,-0.3,4.88,-4.88,0.309,0,0,-1.2,0.1
ENSMUSG00000027597,AHCY,S-adenosylhomocysteine hydrolase,nucleus|cytoplasm|cytosol|cytosol|neuron projection|extracellular vesicular exosome|,chronic inflammatory response to antigenic stimulus|response to nutrient|S-adenosylhomocysteine catabolic process|S-adenosylhomocysteine catabolic process|circadian sleep/wake cycle|homocysteine biosynthetic process|,adenosylhomocysteinase activity|adenosylhomocysteinase activity|copper ion binding|adenyl nucleotide binding|identical protein binding|protein self-association|NAD binding|,6,-0.7,3.12,7,-0.7,2.05,-0.7,4.88,-4.88,0.309,0,0,-2,0
ENSMUSG00000037643,PRKCI,"protein kinase C, iota",Golgi membrane|nucleus|nucleus|cytoplasm|cytoplasm|endosome|cytosol|plasma membrane|tight junction|microtubule cytoskeleton|membrane|apical plasma membrane|cell leading edge|Schmidt-Lanterman incisure|protein complex|intercellular bridge|apical part of cell|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|actin filament organization|multicellular organismal development|positive regulation of neuron projection development|phosphorylation|cell migration|cellular response to insulin stimulus|cellular response to insulin stimulus|negative regulation of glial cell apoptotic process|cellular protein localization|establishment of apical/basal cell polarity|intracellular signal transduction|eye photoreceptor cell development|response to peptide hormone|negative regulation of neuron apoptotic process|cell-cell junction organization|positive regulation of glucose import|Golgi vesicle budding|positive regulation of NF-kappaB transcription factor activity|positive regulation of glial cell proliferation|response to interleukin-1|positive regulation of establishment of protein localization to plasma membrane|positive regulation of endothelial cell apoptotic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein kinase C activity|ATP binding|phospholipid binding|zinc ion binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein domain specific binding|metal ion binding|",10,0,0,10,-0.5,7.51,-0.5,4.79,-4.79,0.313,0,0,-1.5,0.1
ENSMUSG00000020694,TLK2,tousled-like kinase 2 (Arabidopsis),nucleus|nucleus|nucleolus|cytoplasm|cytoskeleton|intermediate filament|intermediate filament|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,regulation of chromatin assembly or disassembly|protein phosphorylation|cellular response to DNA damage stimulus|cell cycle|chromosome segregation|multicellular organismal development|spermatogenesis|phosphorylation|chromatin modification|peptidyl-serine phosphorylation|cell differentiation|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|intracellular signal transduction|cellular response to gamma radiation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.5,0.74,10,0.3,4.45,0.3,4.79,4.79,0.313,0,0,-0.2,1.1
ENSMUSG00000010025,ALDH3A2,"aldehyde dehydrogenase family 3, subfamily A2",nucleus|mitochondrion|mitochondrial inner membrane|peroxisome|endoplasmic reticulum|endoplasmic reticulum|cytosol|membrane|integral component of membrane|extrinsic component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,response to reactive oxygen species|cellular aldehyde metabolic process|sesquiterpenoid metabolic process|central nervous system development|peripheral nervous system development|metabolic process|epidermis development|phytol metabolic process|formaldehyde metabolic process|oxidation-reduction process|,"3-chloroallyl aldehyde dehydrogenase activity|aldehyde dehydrogenase (NAD) activity|aldehyde dehydrogenase [NAD(P)+] activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|long-chain-alcohol oxidase activity|long-chain-aldehyde dehydrogenase activity|medium-chain-aldehyde dehydrogenase activity|",10,0.4,5.47,10,0,0,0.4,4.79,4.79,0.313,0,0,-0.1,1.2
ENSMUSG00000030870,UBFD1,ubiquitin family domain containing 1,cellular_component|,biological_process|,poly(A) RNA binding|,10,1,3.78,10,-0.4,1.73,0.8,4.77,4.77,0.314,0,0,0,2
ENSMUSG00000026787,GAD2,glutamic acid decarboxylase 2,cytoplasm|Golgi apparatus|cytosol|plasma membrane|membrane|cell junction|axon|synaptic vesicle membrane|anchored component of membrane|cytoplasmic vesicle|synapse|perinuclear region of cytoplasm|,glutamate decarboxylation to succinate|carboxylic acid metabolic process|neurotransmitter biosynthetic process|,catalytic activity|glutamate decarboxylase activity|glutamate binding|lyase activity|carboxy-lyase activity|pyridoxal phosphate binding|protein heterodimerization activity|,10,1,7.33,10,0,0,1,4.73,4.73,0.315,0,0,0.2,2
ENSMUSG00000014554,DGUOK,deoxyguanosine kinase,nucleus|cytoplasm|mitochondrion|cytosol|,nucleobase-containing compound metabolic process|protein phosphorylation|deoxyribonucleoside monophosphate biosynthetic process|deoxyribonucleoside monophosphate biosynthetic process|nucleotide biosynthetic process|nucleotide biosynthetic process|negative regulation of neuron projection development|phosphorylation|dGTP metabolic process|purine deoxyribonucleoside metabolic process|,nucleotide binding|deoxyguanosine kinase activity|deoxyguanosine kinase activity|ATP binding|kinase activity|transferase activity|nucleoside kinase activity|,10,0.7,3.03,10,0.3,2.92,0.5,4.7,4.7,0.316,0,0,-0.1,1.4
ENSMUSG00000028992,NMNAT1,nicotinamide nucleotide adenylyltransferase 1,nucleus|nucleus|,NAD biosynthetic process|response to wounding|,nicotinamide-nucleotide adenylyltransferase activity|nicotinamide-nucleotide adenylyltransferase activity|nicotinate-nucleotide adenylyltransferase activity|nicotinate-nucleotide adenylyltransferase activity|,10,0.2,0.793,10,0.4,4.65,0.3,4.67,4.67,0.318,0,0,-0.3,1.2
ENSMUSG00000032808,CYP2C38,"cytochrome P450, family 2, subfamily c, polypeptide 38",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|caffeine oxidase activity|metal ion binding|aromatase activity|",9,0.3,0.47,9,0.8,5.18,0.5,4.64,4.64,0.319,0,0,0,1.9
ENSMUSG00000031392,IRAK1,interleukin-1 receptor-associated kinase 1,nucleus|cytoplasm|lipid particle|membrane|membrane|,"regulation of cytokine-mediated signaling pathway|immune system process|protein phosphorylation|signal transduction|activation of NF-kappaB-inducing kinase activity|JNK cascade|phosphorylation|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|lipopolysaccharide-mediated signaling pathway|lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|response to peptidoglycan|response to lipopolysaccharide|response to lipopolysaccharide|toll-like receptor 2 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway|cellular response to heat|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of MAP kinase activity|positive regulation of JUN kinase activity|innate immune response|negative regulation of transcription, DNA-templated|protein autophosphorylation|protein autophosphorylation|positive regulation of smooth muscle cell proliferation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein oligomerization|interleukin-1-mediated signaling pathway|interleukin-1-mediated signaling pathway|response to interleukin-1|negative regulation of cholesterol efflux|","nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|interleukin-1 receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|heat shock protein binding|protein homodimerization activity|protein heterodimerization activity|",10,-0.7,6.43,10,0,0,-0.6,4.51,-4.51,0.325,0,0,-1.6,0.2
ENSMUSG00000028158,MTTP,microsomal triglyceride transfer protein,endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|Golgi apparatus|basolateral plasma membrane|brush border membrane|microvillus membrane|membrane-bounded vesicle|receptor complex|,protein lipidation|lipid metabolic process|triglyceride metabolic process|transport|lipid transport|lipid transport|steroid metabolic process|cholesterol metabolic process|lipoprotein metabolic process|lipoprotein metabolic process|cholesterol homeostasis|lipoprotein transport|lipoprotein transport|,lipid transporter activity|lipid transporter activity|protein binding|lipid binding|apolipoprotein binding|protein heterodimerization activity|,10,1.1,7.23,9,0.1,0.127,0.7,4.48,4.48,0.326,0,0,-0.2,2
ENSMUSG00000022792,YARS2,tyrosyl-tRNA synthetase 2 (mitochondrial),cytoplasm|mitochondrion|mitochondrion|,translation|tRNA aminoacylation for protein translation|tyrosyl-tRNA aminoacylation|tRNA aminoacylation|mitochondrial tyrosyl-tRNA aminoacylation|,tRNA binding|nucleotide binding|RNA binding|aminoacyl-tRNA ligase activity|tyrosine-tRNA ligase activity|ATP binding|ligase activity|protein homodimerization activity|poly(A) RNA binding|tyrosine binding|,5,1.2,6.9,5,-0.6,5.56,1.2,4.47,4.47,0.327,0,0,-1.3,2
ENSMUSG00000029326,ENOPH1,enolase-phosphatase 1,nucleus|cytoplasm|extracellular vesicular exosome|,metabolic process|cellular amino acid biosynthetic process|methionine biosynthetic process|dephosphorylation|L-methionine salvage from methylthioadenosine|,magnesium ion binding|hydrolase activity|acireductone synthase activity|metal ion binding|,9,-0.5,4.4,9,-0.2,0.944,-0.3,4.44,-4.44,0.328,0,0,-1.4,0.1
ENSMUSG00000034994,EEF2,eukaryotic translation elongation factor 2,nucleus|cytoplasm|polysome|membrane|ribonucleoprotein complex|extracellular vesicular exosome|,hematopoietic progenitor cell differentiation|GTP catabolic process|translation|translational elongation|positive regulation of gene expression|positive regulation of translation|,nucleotide binding|translation elongation factor activity|GTPase activity|protein binding|GTP binding|translation activator activity|protein kinase binding|poly(A) RNA binding|,4,-0.8,5.94,3,0.3,0.705,-0.8,4.44,-4.44,0.328,0,0,-2,1.3
ENSMUSG00000037152,NDUFC1,"NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,-0.1,0.229,10,-0.8,6.27,-0.3,4.4,-4.4,0.33,0,0,-1.8,0
ENSMUSG00000031960,AARS,alanyl-tRNA synthetase,cytoplasm|membrane|extracellular vesicular exosome|,hair follicle development|tRNA modification|translation|alanyl-tRNA aminoacylation|alanyl-tRNA aminoacylation|regulation of translational fidelity|protein folding|cerebellar Purkinje cell layer development|endoplasmic reticulum unfolded protein response|cellular response to unfolded protein|tRNA aminoacylation|response to amino acid|negative regulation of neuron apoptotic process|skin development|neuromuscular process controlling balance|neuromuscular process|,"tRNA binding|nucleotide binding|aminoacyl-tRNA editing activity|nucleic acid binding|RNA binding|aminoacyl-tRNA ligase activity|alanine-tRNA ligase activity|protein binding|ATP binding|amino acid binding|ligase activity|ligase activity, forming aminoacyl-tRNA and related compounds|metal ion binding|",5,-0.8,1.78,5,-0.7,2.97,-0.7,4.37,-4.37,0.331,0,0,-2,0.5
ENSMUSG00000027540,PTPN1,"protein tyrosine phosphatase, non-receptor type 1",early endosome|early endosome|endoplasmic reticulum|cytosol|plasma membrane|membrane|cytoplasmic vesicle|sorting endosome|,protein dephosphorylation|protein dephosphorylation|insulin receptor signaling pathway|regulation of signal transduction|dephosphorylation|regulation of endocytosis|negative regulation of vascular endothelial growth factor receptor signaling pathway|endoplasmic reticulum unfolded protein response|actin cytoskeleton reorganization|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|platelet-derived growth factor receptor-beta signaling pathway|platelet-derived growth factor receptor-beta signaling pathway|regulation of insulin receptor signaling pathway|negative regulation of ERK1 and ERK2 cascade|regulation of hepatocyte growth factor receptor signaling pathway|peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|insulin receptor binding|zinc ion binding|hydrolase activity|phosphatase activity|enzyme binding|protein kinase binding|receptor tyrosine kinase binding|poly(A) RNA binding|ephrin receptor binding|,4,-0.7,6.33,6,0.1,0.177,-0.6,4.32,-4.32,0.334,0,0,-2,0.2
ENSMUSG00000032477,CDC25A,cell division cycle 25A,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|,G1/S transition of mitotic cell cycle|mitotic M phase|protein dephosphorylation|cell cycle|mitotic nuclear division|response to radiation|dephosphorylation|cellular response to UV|cell division|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|protein kinase binding|,10,-0.5,2.82,10,0.9,6.48,0.5,4.32,4.32,0.334,0,0,-0.5,2
ENSMUSG00000026207,SPEG,SPEG complex locus,nucleus|,in utero embryonic development|protein phosphorylation|phosphorylation|cell differentiation|cardiac muscle cell development|respiratory system development|cardiovascular system development|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.3,1.96,10,0.3,2.54,0.3,4.24,4.24,0.338,0,0,-0.2,1.3
ENSMUSG00000024735,PRPF19,PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae),Prp19 complex|nucleus|nucleus|nucleus|spliceosomal complex|cytoplasm|cytoplasm|lipid particle|cytoskeleton|membrane|nuclear speck|catalytic step 2 spliceosome|,"protein polyubiquitination|spliceosomal complex assembly|mRNA splicing, via spliceosome|inner cell mass cell proliferation|DNA repair|mRNA processing|cellular response to DNA damage stimulus|RNA splicing|lipid biosynthetic process|protein ubiquitination|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of mRNA splicing, via spliceosome|positive regulation of astrocyte differentiation|",DNA binding|ubiquitin-protein transferase activity|protein binding|ubiquitin-ubiquitin ligase activity|identical protein binding|,4,0.5,2.58,4,0.4,1.99,0.5,4.17,4.17,0.341,0,0,-0.4,2
ENSMUSG00000031266,GLA,"galactosidase, alpha",extracellular region|cytoplasm|lysosome|lysosome|Golgi apparatus|extracellular vesicular exosome|,carbohydrate metabolic process|metabolic process|oligosaccharide metabolic process|oligosaccharide metabolic process|glycoside catabolic process|negative regulation of nitric oxide biosynthetic process|glycosylceramide catabolic process|glycosylceramide catabolic process|negative regulation of nitric-oxide synthase activity|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-galactosidase activity|alpha-galactosidase activity|alpha-galactosidase activity|receptor binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|galactoside binding|protein homodimerization activity|raffinose alpha-galactosidase activity|",10,0.4,3.72,10,0.4,0.664,0.4,4.17,4.17,0.341,0,0,-0.3,1.4
ENSMUSG00000005510,NDUFS3,NADH dehydrogenase (ubiquinone) Fe-S protein 3,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial respiratory chain complex I|membrane|mitochondrial membrane|respiratory chain|,transport|negative regulation of cell growth|oxidation-reduction process|reactive oxygen species metabolic process|negative regulation of intrinsic apoptotic signaling pathway|,"NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H|",8,-0.5,5.31,8,0.6,4.23,-0.4,4.16,-4.16,0.342,0,0,-1.7,1.2
ENSMUSG00000033161,ATP1A1,"ATPase, Na+/K+ transporting, alpha 1 polypeptide",endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|sodium:potassium-exchanging ATPase complex|caveola|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|T-tubule|sarcolemma|protein complex|membrane raft|extracellular vesicular exosome|,regulation of the force of heart contraction|regulation of sodium ion transport|ATP catabolic process|ATP biosynthetic process|transport|ion transport|cation transport|potassium ion transport|sodium ion transport|regulation of blood pressure|potassium ion import|monovalent inorganic cation transport|dephosphorylation|negative regulation of glucocorticoid biosynthetic process|sodium ion transmembrane transport|sodium ion transmembrane transport|response to drug|negative regulation of heart contraction|positive regulation of heart contraction|positive regulation of striated muscle contraction|membrane hyperpolarization|cellular response to mechanical stimulus|potassium ion transmembrane transport|regulation of cardiac muscle cell contraction|,"nucleotide binding|sodium:potassium-exchanging ATPase activity|sodium:potassium-exchanging ATPase activity|sodium:potassium-exchanging ATPase activity|protein binding|ATP binding|monovalent inorganic cation transmembrane transporter activity|hydrolase activity|phosphatase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|cation-transporting ATPase activity|protein kinase binding|protein domain specific binding|ankyrin binding|potassium ion binding|sodium ion binding|ADP binding|phosphatidylinositol 3-kinase binding|metal ion binding|chaperone binding|",6,0.7,4.59,7,-0.6,1.3,0.6,4.13,4.13,0.343,0,0,-0.9,1.9
ENSMUSG00000028030,TBCK,TBC1 domain containing kinase,cellular_component|,regulation of Rab GTPase activity|,"Rab GTPase activator activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.291,10,-0.4,4.72,-0.4,4.13,-4.13,0.343,0,0,-1.3,0.4
ENSMUSG00000016526,DYRK3,dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3,nucleus|,protein phosphorylation|protein phosphorylation|phosphorylation|peptidyl-tyrosine phosphorylation|erythrocyte differentiation|erythrocyte differentiation|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0,0,10,0.6,5.09,0.4,4.08,4.08,0.346,0,0,-0.1,1.5
ENSMUSG00000021764,NDUFS4,NADH dehydrogenase (ubiquinone) Fe-S protein 4,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial respiratory chain complex I|membrane|respiratory chain complex I|respiratory chain|,regulation of protein phosphorylation|transport|brain development|cAMP-mediated signaling|electron transport chain|mitochondrial respiratory chain complex I assembly|cellular respiration|positive regulation of fibroblast proliferation|response to cAMP|oxidation-reduction process|reactive oxygen species metabolic process|,"NADH dehydrogenase (ubiquinone) activity|NADH dehydrogenase (ubiquinone) activity|NADH dehydrogenase (ubiquinone) activity|oxidoreductase activity, acting on NAD(P)H|",10,-0.6,2.38,10,-0.4,2,-0.6,4.07,-4.07,0.346,0,0,-1.6,0.2
ENSMUSG00000026687,ALDH9A1,"aldehyde dehydrogenase 9, subfamily A1",cytoplasm|mitochondrion|cytosol|cytosol|extracellular vesicular exosome|,cellular aldehyde metabolic process|metabolic process|carnitine metabolic process|neurotransmitter biosynthetic process|oxidation-reduction process|oxidation-reduction process|,"aldehyde dehydrogenase (NAD) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|aminobutyraldehyde dehydrogenase activity|protein homodimerization activity|amine binding|4-trimethylammoniobutyraldehyde dehydrogenase activity|NAD binding|",10,-0.2,1.47,10,-0.4,3.18,-0.3,4.05,-4.05,0.347,0,0,-1.7,0.5
ENSMUSG00000053398,PHGDH,3-phosphoglycerate dehydrogenase,extracellular vesicular exosome|,glutamine metabolic process|glycine metabolic process|L-serine metabolic process|L-serine biosynthetic process|threonine metabolic process|metabolic process|cellular amino acid biosynthetic process|gamma-aminobutyric acid metabolic process|regulation of gene expression|taurine metabolic process|spinal cord development|glial cell development|neural tube development|neurogenesis|neuron projection development|oxidation-reduction process|G1 to G0 transition|,"phosphoglycerate dehydrogenase activity|phosphoglycerate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|NAD binding|",10,0.4,4.11,10,0.2,0.534,0.3,4.05,4.05,0.347,0,0,-0.3,1.3
ENSMUSG00000020255,D10WSU102E,"DNA segment, Chr 10, Wayne State University 102, expressed",cellular_component|,biological_process|,molecular_function|,8,-1.2,6.79,8,0.4,1.9,-1.2,4.03,-4.03,0.348,0,0,-2,0.6
ENSMUSG00000048376,F2R,coagulation factor II (thrombin) receptor,plasma membrane|caveola|membrane|integral component of membrane|platelet dense tubular network|neuromuscular junction|postsynaptic membrane|,"activation of MAPKK activity|connective tissue replacement involved in inflammatory response wound healing|negative regulation of glomerular filtration|activation of cysteine-type endopeptidase activity involved in apoptotic process|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|protein kinase C-activating G-protein coupled receptor signaling pathway|tyrosine phosphorylation of STAT protein|STAT protein import into nucleus|establishment of synaptic specificity at neuromuscular junction|blood coagulation|hemostasis|positive regulation of cell proliferation|negative regulation of cell proliferation|response to wounding|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of phosphatidylinositol 3-kinase signaling|death|platelet activation|regulation of blood coagulation|positive regulation of blood coagulation|positive regulation of blood coagulation|positive regulation of cell migration|positive regulation of cell migration|response to lipopolysaccharide|regulation of interleukin-1 beta production|positive regulation of collagen biosynthetic process|positive regulation of Rho protein signal transduction|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of MAPK cascade|negative regulation of neuron apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of vasoconstriction|positive regulation of vasoconstriction|positive regulation of smooth muscle contraction|positive regulation of JAK-STAT cascade|homeostasis of number of cells within a tissue|release of sequestered calcium ion into cytosol|positive regulation of release of sequestered calcium ion into cytosol|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|positive regulation of calcium ion transport|regulation of sensory perception of pain|positive regulation of ERK1 and ERK2 cascade|thrombin receptor signaling pathway|thrombin receptor signaling pathway|negative regulation of renin secretion into blood stream|positive regulation of interleukin-8 secretion|positive regulation of interleukin-6 secretion|",G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|receptor binding|thrombin receptor activity|G-protein beta-subunit binding|heterotrimeric G-protein binding|,10,0.2,1.17,10,0.5,3.52,0.4,4.03,4.03,0.348,0,0,-0.3,1.3
ENSMUSG00000036499,EEA1,early endosome antigen 1,cytoplasm|endosome|early endosome|early endosome|early endosome|cytosol|serine-pyruvate aminotransferase complex|membrane|extrinsic component of plasma membrane|cytoplasmic vesicle|axonal spine|recycling endosome|extracellular vesicular exosome|,endocytosis|vesicle fusion|,protein binding|1-phosphatidylinositol binding|GTP-dependent protein binding|protein homodimerization activity|metal ion binding|,10,-0.5,0.81,10,0.8,3.69,0.8,4.01,4.01,0.349,0,0,-0.5,2
ENSMUSG00000031805,JAK3,Janus kinase 3,intracellular|intracellular|cytoplasm|cytoskeleton|membrane|,immune system process|negative regulation of dendritic cell cytokine production|protein phosphorylation|enzyme linked receptor protein signaling pathway|positive regulation of cytosolic calcium ion concentration|phosphorylation|peptidyl-tyrosine phosphorylation|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|B cell differentiation|negative regulation of interleukin-10 production|negative regulation of interleukin-12 production|intracellular signal transduction|interleukin-4-mediated signaling pathway|positive regulation of T cell proliferation|positive regulation of activated T cell proliferation|tyrosine phosphorylation of Stat5 protein|T cell homeostasis|innate immune response|negative regulation of FasL biosynthetic process|negative regulation of T-helper 1 cell differentiation|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|lymph node development|positive regulation of immune response|negative regulation of T cell activation|positive regulation of calcium ion transport|regulation of T cell apoptotic process|negative regulation of thymocyte apoptotic process|response to interleukin-2|response to interleukin-4|response to interleukin-4|response to interleukin-15|response to interleukin-9|positive regulation of dendritic cell apoptotic process|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|",9,-0.3,1.81,10,0.5,5.39,0.5,4,4,0.35,0,0,-0.7,1.5
ENSMUSG00000026189,PECR,peroxisomal trans-2-enoyl-CoA reductase,mitochondrion|peroxisome|peroxisome|peroxisomal membrane|intracellular membrane-bounded organelle|intracellular membrane-bounded organelle|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|fatty acid elongation|phytol metabolic process|oxidation-reduction process|oxidation-reduction process|,receptor binding|oxidoreductase activity|trans-2-enoyl-CoA reductase (NADPH) activity|trans-2-enoyl-CoA reductase (NADPH) activity|trans-2-enoyl-CoA reductase (NADPH) activity|,10,0.2,0.512,10,-0.8,4.44,-0.8,3.97,-3.97,0.351,0,0,-1.9,0.2
ENSMUSG00000044147,ARF6,ADP-ribosylation factor 6,ruffle|intracellular|cytoplasm|endosome|endosome|endosome|early endosome|Golgi apparatus|plasma membrane|plasma membrane|cell cortex|membrane|membrane|endocytic vesicle|filopodium membrane|cell projection|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|,liver development|GTP catabolic process|transport|cell cycle|small GTPase mediated signal transduction|nervous system development|protein transport|vesicle-mediated transport|cell differentiation|positive regulation of actin filament polymerization|cortical actin cytoskeleton organization|ruffle organization|myeloid cell apoptotic process|regulation of toll-like receptor 4 signaling pathway|protein localization to cell surface|regulation of Rac protein signal transduction|protein localization to endosome|protein localization to endosome|cell division|regulation of filopodium assembly|regulation of dendritic spine development|regulation of dendritic spine development|positive regulation of establishment of protein localization to plasma membrane|establishment of epithelial cell polarity|hepatocyte apoptotic process|,nucleotide binding|GTPase activity|protein binding|GTP binding|thioesterase binding|,10,-0.4,3.8,10,-0.2,0.465,-0.4,3.97,-3.97,0.351,0,0,-1.4,0.3
ENSMUSG00000020428,GABRA6,"gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|dendrite|neuronal cell body membrane|chloride channel complex|presynaptic membrane|receptor complex|synapse|postsynaptic membrane|,"transport|ion transport|chloride transport|gamma-aminobutyric acid signaling pathway|ion transmembrane transport|protein heterooligomerization|synaptic transmission, GABAergic|",GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|inhibitory extracellular ligand-gated ion channel activity|chloride channel activity|drug binding|benzodiazepine receptor activity|GABA-gated chloride ion channel activity|,9,0.3,1.01,9,-0.4,3.87,-0.4,3.93,-3.93,0.354,0,0,-1.6,0.6
ENSMUSG00000038481,CDK19,cyclin-dependent kinase 19,cellular_component|,protein phosphorylation|cell cycle|phosphorylation|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.2,3.15,10,-0.8,6.6,-0.2,3.92,-3.92,0.354,0,0,-2,1.2
ENSMUSG00000034115,SCN11A,"sodium channel, voltage-gated, type XI, alpha",voltage-gated sodium channel complex|plasma membrane|membrane|integral component of membrane|axon|C-fiber|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|regulation of sensory perception of pain|transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|sodium channel activity|protein binding|,9,-0.8,1.36,9,0.3,3.37,0.3,3.92,3.92,0.354,0,0,-1.1,1.6
ENSMUSG00000031969,ACAD8,"acyl-Coenzyme A dehydrogenase family, member 8",mitochondrion|,metabolic process|branched-chain amino acid catabolic process|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|short-branched-chain-acyl-CoA dehydrogenase activity|very-long-chain-acyl-CoA dehydrogenase activity|4-methyloctanoyl-CoA dehydrogenase activity|naphthyl-2-methyl-succinyl-CoA dehydrogenase activity|2-methylhexanoyl-CoA dehydrogenase activity|propionyl-CoA dehydrogenase activity|thiol-driven fumarate reductase activity|flavin adenine dinucleotide binding|coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity|coenzyme F420-dependent 2,4-dinitrophenol reductase activity|medium-chain-acyl-CoA dehydrogenase activity|",10,0.4,1.9,10,-0.3,2.57,0.4,3.92,3.92,0.354,0,0,-0.8,1.5
ENSMUSG00000053624,GYKL1,glycerol kinase-like 1,mitochondrion|extracellular vesicular exosome|,glycerol metabolic process|triglyceride metabolic process|phosphorylation|glycerol-3-phosphate biosynthetic process|,glycerol kinase activity|kinase activity|transferase activity|,10,-0.9,1.67,10,0.6,5.23,0.6,3.88,3.88,0.357,0,0,-0.9,2
ENSMUSG00000034570,INPP5J,inositol polyphosphate 5-phosphatase J,ruffle|cytoplasm|plasma membrane|extrinsic component of membrane|growth cone|growth cone|dendritic shaft|,negative regulation of neuron projection development|negative regulation of neuron projection development|negative regulation of neuron projection development|dephosphorylation|negative regulation of microtubule polymerization|negative regulation of peptidyl-serine phosphorylation|negative regulation of peptidyl-serine phosphorylation|phosphatidylinositol dephosphorylation|,"inositol-polyphosphate 5-phosphatase activity|hydrolase activity|SH3 domain binding|phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity|",9,0.5,2.87,9,0.3,1.44,0.4,3.86,3.86,0.358,0,0,-2.9,2
ENSMUSG00000058715,FCER1G,"Fc receptor, IgE, high affinity I, gamma polypeptide",plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|Fc-epsilon receptor I complex|membrane raft|,"positive regulation of type IIa hypersensitivity|positive regulation of type III hypersensitivity|positive regulation of type I hypersensitivity|neutrophil activation involved in immune response|Fc receptor mediated stimulatory signaling pathway|serotonin secretion by platelet|phagocytosis, engulfment|signal transduction|cell surface receptor signaling pathway|cell surface receptor signaling pathway|integrin-mediated signaling pathway|regulation of platelet activation|immunoglobulin mediated immune response|antigen processing and presentation of exogenous peptide antigen via MHC class II|neutrophil chemotaxis|positive regulation of interleukin-10 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of mast cell cytokine production|positive regulation of mast cell cytokine production|negative regulation of mast cell apoptotic process|negative regulation of mast cell apoptotic process|Fc-epsilon receptor signaling pathway|antigen processing and presentation of exogenous peptide antigen via MHC class I|defense response to bacterium|positive regulation of mast cell degranulation|positive regulation of mast cell degranulation|mast cell activation|mast cell activation|positive regulation of phagocytosis|regulation of immune response|positive regulation of immune response|protein localization to plasma membrane|",transmembrane signaling receptor activity|protein binding|IgE receptor activity|IgE receptor activity|IgE binding|IgE binding|IgE binding|IgG binding|,10,0.4,0.295,10,-0.8,5.41,0.5,3.78,3.78,0.362,0,0,-1.7,1.5
ENSMUSG00000024247,PKDCC,"protein kinase domain containing, cytoplasmic",Golgi apparatus|,skeletal system development|ossification|protein phosphorylation|transport|multicellular organismal development|protein transport|phosphorylation|cell differentiation|bone mineralization|positive regulation of bone mineralization|positive regulation of chondrocyte differentiation|limb morphogenesis|multicellular organism growth|negative regulation of Golgi to plasma membrane protein transport|lung alveolus development|embryonic digestive tract development|palate development|,"nucleotide binding|protein kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,1,6.29,9,-0.7,3.17,0.5,3.76,3.76,0.363,0,0,-1,2
ENSMUSG00000041187,PRKD2,protein kinase D2,nucleus|cytoplasm|Golgi apparatus|plasma membrane|membrane|,angiogenesis|positive regulation of endothelial cell proliferation|immune system process|protein phosphorylation|cell adhesion|cell death|positive regulation of endothelial cell migration|phosphorylation|peptidyl-serine phosphorylation|positive regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of interleukin-2 production|positive regulation of interleukin-8 production|positive regulation of CREB transcription factor activity|positive regulation of peptidyl-serine phosphorylation|intracellular signal transduction|cellular response to vascular endothelial growth factor stimulus|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway|positive regulation of blood vessel endothelial cell migration|positive regulation of fibroblast growth factor receptor signaling pathway|positive regulation of angiogenesis|positive regulation of cell adhesion|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|vascular endothelial growth factor receptor signaling pathway|T cell receptor signaling pathway|positive regulation of T cell receptor signaling pathway|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of ERK1 and ERK2 cascade|positive regulation of histone deacetylase activity|positive regulation of intracellular signal transduction|positive regulation of DNA biosynthetic process|positive regulation of endothelial cell chemotaxis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",9,0.4,1.96,10,0.6,2.19,0.5,3.72,3.72,0.366,0,0,-0.7,1.6
ENSMUSG00000021108,PRKCH,"protein kinase C, eta",cytoplasm|cytosol|cytosol|plasma membrane|plasma membrane|cell-cell junction|membrane|extracellular vesicular exosome|,protein phosphorylation|positive regulation of macrophage derived foam cell differentiation|phosphorylation|cell differentiation|negative regulation of glial cell apoptotic process|intracellular signal transduction|positive regulation of keratinocyte differentiation|positive regulation of B cell receptor signaling pathway|positive regulation of NF-kappaB transcription factor activity|positive regulation of glial cell proliferation|protein kinase C signaling|regulation of tight junction assembly|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|calcium-independent protein kinase C activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Ral GTPase binding|enzyme binding|metal ion binding|",10,-1,6.87,10,0.4,4.07,-0.7,3.71,-3.71,0.366,0,0,-2,0.8
ENSMUSG00000063434,SORCS3,sortilin-related VPS10 domain containing receptor 3,membrane|integral component of membrane|neuronal postsynaptic density|,learning|memory|regulation of long term synaptic depression|,protein binding|,10,0.2,0.692,10,0.4,3.5,0.3,3.7,3.7,0.367,0,0,-0.3,1.4
ENSMUSG00000092305,PRPS1L1,phosphoribosyl pyrophosphate synthetase 1-like 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.51,10,0.6,4.36,0.3,3.7,3.7,0.367,0,0,-0.5,1.5
ENSMUSG00000031233,PGK2,phosphoglycerate kinase 2,nucleus|cytoplasm|cilium|sperm fibrous sheath|,glycolytic process|glycolytic process|phosphorylation|sperm motility|,nucleotide binding|phosphoglycerate kinase activity|phosphoglycerate kinase activity|ATP binding|kinase activity|transferase activity|,10,0.5,5.68,10,0,0,0.5,3.69,3.69,0.367,0,0,-0.4,1.5
ENSMUSG00000040652,OAZ2,ornithine decarboxylase antizyme 2,nucleus|,polyamine metabolic process|negative regulation of catalytic activity|negative regulation of catalytic activity|,enzyme inhibitor activity|protein binding|ornithine decarboxylase inhibitor activity|ornithine decarboxylase inhibitor activity|,10,0,0,10,-0.6,4.99,-0.4,3.69,-3.69,0.367,0,0,-1.6,0.3
ENSMUSG00000068917,CLK2,CDC-like kinase 2,nucleus|nucleus|,protein phosphorylation|protein phosphorylation|response to organic substance|response to ionizing radiation|phosphorylation|peptidyl-tyrosine phosphorylation|response to retinoic acid|regulation of RNA splicing|negative regulation of gluconeogenesis|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,-1,5.07,9,-0.1,0.236,-0.4,3.68,-3.68,0.368,0,0,-1.9,0
ENSMUSG00000057177,GSK3A,glycogen synthase kinase 3 alpha,None,regulation of systemic arterial blood pressure|cardiac left ventricle morphogenesis|carbohydrate metabolic process|glycogen metabolic process|regulation of gene expression by genetic imprinting|protein phosphorylation|protein phosphorylation|protein phosphorylation|nervous system development|insulin receptor signaling pathway|negative regulation of signal transduction|positive regulation of peptidyl-threonine phosphorylation|Wnt signaling pathway|phosphorylation|cell migration|positive regulation of cAMP biosynthetic process|negative regulation of TOR signaling|cellular response to insulin stimulus|positive regulation of peptidyl-serine phosphorylation|cellular response to interleukin-3|proteasome-mediated ubiquitin-dependent protein catabolic process|hypermethylation of CpG island|positive regulation of heart contraction|positive regulation of transcription from RNA polymerase II promoter|negative regulation of glucose import|negative regulation of insulin receptor signaling pathway|negative regulation of transferase activity|negative regulation of cell growth involved in cardiac muscle cell development|cellular response to lithium ion|cellular response to organic cyclic compound|positive regulation of adrenergic receptor signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|positive regulation of glycogen (starch) synthase activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase A catalytic subunit binding|tau-protein kinase activity|",10,-0.4,1.05,10,-0.8,3.84,-0.5,3.67,-3.67,0.369,0,0,-1.9,0.5
ENSMUSG00000021408,RIPK1,receptor (TNFRSF)-interacting serine-threonine kinase 1,cytoplasm|mitochondrion|plasma membrane|membrane|death-inducing signaling complex|protein complex|receptor complex|membrane raft|ripoptosome|ripoptosome|,positive regulation of protein phosphorylation|protein phosphorylation|apoptotic process|signal transduction|positive regulation of cell death|programmed cell death|viral process|phosphorylation|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|response to tumor necrosis factor|peptidyl-serine autophosphorylation|positive regulation of phosphorylation|positive regulation of apoptotic process|positive regulation of programmed cell death|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of MAPK cascade|cellular protein catabolic process|positive regulation of macrophage differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JNK cascade|positive regulation of JNK cascade|protein autophosphorylation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein homooligomerization|protein heterooligomerization|positive regulation of transferase activity|positive regulation of necroptotic process|T cell apoptotic process|necroptotic process|necroptotic process|regulation of ATP:ADP antiporter activity|cellular response to tumor necrosis factor|cellular response to growth factor stimulus|extrinsic apoptotic signaling pathway|ripoptosome assembly|necroptotic signaling pathway|necroptotic signaling pathway|ripoptosome assembly involved in necroptotic process|amyloid fibril formation|regulation of reactive oxygen species metabolic process|negative regulation of extrinsic apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|death receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|ubiquitin protein ligase binding|protein complex binding|identical protein binding|death domain binding|",7,-1.2,6.08,5,0,0,-1.2,3.66,-3.66,0.369,0,0,-2,0
ENSMUSG00000040249,LRP1,low density lipoprotein receptor-related protein 1,nucleus|cytoplasm|lysosomal membrane|endosome|plasma membrane|integral component of plasma membrane|coated pit|membrane|integral component of membrane|clathrin-coated vesicle|dendrite|neuronal cell body|receptor complex|perinuclear region of cytoplasm|,endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|protein kinase C-activating G-protein coupled receptor signaling pathway|multicellular organismal development|cholesterol metabolic process|cell proliferation|positive regulation of cholesterol efflux|negative regulation of smooth muscle cell migration|negative regulation of Wnt signaling pathway|positive regulation of lipid transport|regulation of cholesterol transport|regulation of phospholipase A2 activity|regulation of actin cytoskeleton organization|aorta morphogenesis|apoptotic cell clearance|negative regulation of neuron apoptotic process|positive regulation of protein transport|beta-amyloid clearance|negative regulation of platelet-derived growth factor receptor-beta signaling pathway|,protease binding|calcium ion binding|protein binding|protein complex binding|apolipoprotein binding|poly(A) RNA binding|metal ion binding|,10,0.2,0.963,10,0.3,3.12,0.3,3.65,3.65,0.37,0,0,-0.5,1.2
ENSMUSG00000025968,NDUFS1,NADH dehydrogenase (ubiquinone) Fe-S protein 1,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial respiratory chain complex I|mitochondrial intermembrane space|membrane|respiratory chain|,transport|apoptotic mitochondrial changes|ATP synthesis coupled electron transport|cellular respiration|cellular respiration|ATP metabolic process|regulation of mitochondrial membrane potential|oxidation-reduction process|reactive oxygen species metabolic process|,"NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|NADH dehydrogenase (ubiquinone) activity|electron carrier activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|4 iron, 4 sulfur cluster binding|",7,0.5,3.13,6,0.3,1.13,0.4,3.63,3.63,0.371,0,0,-0.8,1.7
ENSMUSG00000020385,CLK4,CDC like kinase 4,nucleus|,protein phosphorylation|phosphorylation|peptidyl-tyrosine phosphorylation|regulation of RNA splicing|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.8,0.833,10,-0.4,3.3,-0.4,3.62,-3.62,0.372,0,0,-1.7,0.4
ENSMUSG00000029162,KHK,ketohexokinase,nucleus|cytoplasm|cytoplasm|extracellular vesicular exosome|,carbohydrate metabolic process|fructose metabolic process|fructose metabolic process|response to sucrose|response to glucose|response to zinc ion|phosphorylation|response to insulin|carbohydrate phosphorylation|carbohydrate phosphorylation|regulation of glycogen metabolic process|,nucleotide binding|ketohexokinase activity|ketohexokinase activity|ATP binding|kinase activity|transferase activity|,9,-0.2,0.416,9,-0.8,5.44,-0.8,3.62,-3.62,0.372,0,0,-2,0
ENSMUSG00000001986,GRIA3,"glutamate receptor, ionotropic, AMPA3 (alpha 3)",plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|dendrite|asymmetric synapse|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|neuronal cell body|synaptic cleft|terminal bouton|dendritic spine|dendritic shaft|perikaryon|protein complex|synapse|postsynaptic membrane|postsynaptic membrane|,"regulation of receptor recycling|transport|ion transport|ion transmembrane transport|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|",receptor activity|ionotropic glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|PDZ domain binding|,10,0.3,2.06,10,0.4,1.91,0.3,3.61,3.61,0.372,0,0,-0.1,1.6
ENSMUSG00000020591,NTSR2,neurotensin receptor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|regulation of membrane potential|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled neurotensin receptor activity|,10,-0.1,0.301,10,0.5,5.95,0.4,3.6,3.6,0.373,0,0,-0.5,1.6
ENSMUSG00000021057,AKAP5,A kinase (PRKA) anchor protein 5,cytoplasm|plasma membrane|postsynaptic density|membrane|basolateral plasma membrane|filopodium membrane|asymmetric synapse|dendrite membrane|dendritic spine membrane|neuronal cell body|dendritic spine|dendritic shaft|protein complex|perinuclear region of cytoplasm|,positive regulation of protein phosphorylation|protein targeting|signal transduction|negative regulation of adenylate cyclase activity|positive regulation of calcium ion transport into cytosol|positive regulation of protein kinase A signaling|positive regulation of cAMP biosynthetic process|negative regulation of potassium ion transport|negative regulation of ion transport|cellular protein complex disassembly|positive regulation of adenylate cyclase activity|positive regulation of dendrite morphogenesis|positive regulation of NFAT protein import into nucleus|,G-protein coupled receptor binding|actin binding|protein binding|calmodulin binding|adenylate cyclase binding|kinase binding|protein kinase binding|protein domain specific binding|protein phosphatase 2B binding|protein complex binding|protein kinase A regulatory subunit binding|cadherin binding|GABA receptor binding|,10,-0.3,0.758,10,0.7,5.26,0.4,3.58,3.58,0.374,0,0,-0.6,1.8
ENSMUSG00000027303,PTPRA,"protein tyrosine phosphatase, receptor type, A",plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|receptor complex|extracellular vesicular exosome|,protein phosphorylation|protein dephosphorylation|insulin receptor signaling pathway|dephosphorylation|peptidyl-tyrosine dephosphorylation|positive regulation of oligodendrocyte differentiation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|protein complex binding|,10,-0.8,1.22,10,-0.3,2.99,-0.4,3.57,-3.57,0.374,0,0,-1.7,0.2
ENSMUSG00000032737,INPPL1,inositol polyphosphate phosphatase-like 1,cytoplasm|cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|membrane|lamellipodium|cell projection|,endochondral ossification|immune system process|glucose metabolic process|phosphatidylinositol biosynthetic process|endocytosis|actin filament organization|cell adhesion|negative regulation of DNA replication|negative regulation of cell proliferation|post-embryonic development|negative regulation of gene expression|negative regulation of platelet-derived growth factor receptor signaling pathway|negative regulation of neuron projection development|dephosphorylation|response to insulin|inositol trisphosphate metabolic process|negative regulation of MAP kinase activity|negative regulation of insulin-like growth factor receptor signaling pathway|cellular lipid metabolic process|negative regulation of insulin receptor signaling pathway|phosphatidylinositol dephosphorylation|ruffle assembly|,"actin binding|inositol-polyphosphate 5-phosphatase activity|protein binding|phosphatidylinositol-3,4,5-trisphosphate binding|hydrolase activity|SH3 domain binding|SH2 domain binding|",10,0.4,2.31,10,0.3,1.56,0.4,3.53,3.53,0.377,0,0,-0.2,1.4
ENSMUSG00000022489,PDE1B,"phosphodiesterase 1B, Ca2+-calmodulin dependent",cytoplasm|neuronal cell body|,regulation of neurotransmitter levels|response to amphetamine|response to amphetamine|cAMP catabolic process|signal transduction|locomotory behavior|visual learning|visual learning|cellular response to macrophage colony-stimulating factor stimulus|regulation of dopamine metabolic process|serotonin metabolic process|cGMP catabolic process|cellular response to granulocyte macrophage colony-stimulating factor stimulus|,"cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|calmodulin binding|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity|",10,-0.2,0.698,10,0.6,5.25,0.4,3.52,3.52,0.378,0,0,-0.4,1.6
ENSMUSG00000040820,HLCS,holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase),chromatin|nuclear lamina|cytoplasm|mitochondrion|cytosol|nuclear matrix|,cellular protein modification process|metabolic process|cell proliferation|protein biotinylation|histone modification|response to biotin|histone biotinylation|,nucleotide binding|catalytic activity|biotin-[acetyl-CoA-carboxylase] ligase activity|biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity|biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity|biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity|ATP binding|biotin binding|ligase activity|lipoate-protein ligase activity|biotin-protein ligase activity|enzyme binding|tRNA(Ile)-lysidine synthase activity|protein homodimerization activity|biotin-[pyruvate-carboxylase] ligase activity|,10,-0.5,4.39,10,-0.1,0.418,-0.4,3.51,-3.51,0.378,0,0,-1.7,0.6
ENSMUSG00000026309,ILKAP,integrin-linked kinase-associated serine/threonine phosphatase 2C,cellular_component|cytoplasm|,protein dephosphorylation|regulation of nuclear cell cycle DNA replication|,catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,-0.5,3.32,10,0.7,2.39,-0.3,3.51,-3.51,0.378,0,0,-1.2,1.5
ENSMUSG00000069515,LYZ1,lysozyme 1,Golgi cis cisterna|extracellular region|extracellular space|cytoplasm|endoplasmic reticulum lumen|Golgi stack|microvillus|trans-Golgi network transport vesicle|secretory granule|rough endoplasmic reticulum lumen|extracellular vesicular exosome|,metabolic process|cell wall macromolecule catabolic process|cytolysis|defense response to bacterium|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|,"lysozyme activity|catalytic activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|identical protein binding|",10,-0.8,1.14,10,-0.3,2.61,-0.3,3.47,-3.47,0.381,0,0,-1.7,0.2
ENSMUSG00000035000,DPP4,dipeptidylpeptidase 4,extracellular region|lysosomal membrane|endoplasmic reticulum|Golgi apparatus|plasma membrane|cell surface|membrane|membrane|integral component of membrane|apical plasma membrane|lamellipodium|cell junction|endocytic vesicle|cell projection|intercellular canaliculus|extracellular vesicular exosome|invadopodium membrane|,response to hypoxia|regulation of T cell mediated immunity|proteolysis|cell adhesion|positive regulation of cell proliferation|negative regulation of extracellular matrix disassembly|T cell costimulation|regulation of cell-cell adhesion mediated by integrin|T cell activation|endothelial cell migration|establishment of localization|,protease binding|aminopeptidase activity|serine-type endopeptidase activity|receptor binding|collagen binding|peptidase activity|serine-type peptidase activity|dipeptidyl-peptidase activity|hydrolase activity|peptide binding|identical protein binding|protein homodimerization activity|,10,0.1,0.0599,10,0.5,3.96,0.5,3.46,3.46,0.381,0,0,-0.2,1.6
ENSMUSG00000016528,MAPKAPK2,MAP kinase-activated protein kinase 2,nucleus|nucleus|cytoplasm|cytoplasm|centrosome|,toll-like receptor signaling pathway|protein phosphorylation|response to stress|inflammatory response|cellular response to DNA damage stimulus|phosphorylation|peptidyl-serine phosphorylation|G2 DNA damage checkpoint|response to lipopolysaccharide|regulation of interleukin-6 production|regulation of tumor necrosis factor production|regulation of tumor necrosis factor production|response to cytokine|cellular response to vascular endothelial growth factor stimulus|macropinocytosis|vascular endothelial growth factor receptor signaling pathway|mRNA stabilization|inner ear development|3'-UTR-mediated mRNA stabilization|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,1.34,10,-0.6,3.94,-0.4,3.43,-3.43,0.383,0,0,-1.6,0.1
ENSMUSG00000043004,GNG2,"guanine nucleotide binding protein (G protein), gamma 2",heterotrimeric G-protein complex|plasma membrane|membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|cell proliferation|,GTPase activity|signal transducer activity|G-protein beta-subunit binding|,10,0.4,2.99,10,0.2,0.768,0.3,3.43,3.43,0.383,0,0,-0.4,1.3
ENSMUSG00000073402,GM8909,predicted gene 8909,None,None,None,10,1.4,5.72,10,0.2,0.213,1.3,3.41,3.41,0.385,0,0,0.1,2
ENSMUSG00000021577,SDHA,"succinate dehydrogenase complex, subunit A, flavoprotein (Fp)",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|membrane|,tricarboxylic acid cycle|succinate metabolic process|transport|nervous system development|electron transport chain|respiratory electron transport chain|oxidation-reduction process|,"succinate dehydrogenase activity|succinate dehydrogenase (ubiquinone) activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|flavin adenine dinucleotide binding|",7,0.5,2.25,8,0.4,1.4,0.4,3.39,3.39,0.386,0,0,-0.4,1.7
ENSMUSG00000030110,RET,ret proto-oncogene,intracellular|endosome|plasma membrane|integral component of plasma membrane|endosome membrane|membrane|integral component of membrane|receptor complex|membrane raft|,"MAPK cascade|ureteric bud development|neural crest cell migration|embryonic epithelial tube formation|embryonic epithelial tube formation|protein phosphorylation|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell adhesion|homophilic cell adhesion|neuron cell-cell adhesion|neuron cell-cell adhesion|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|anatomical structure morphogenesis|positive regulation of neuron projection development|positive regulation of neuron maturation|phosphorylation|peptidyl-tyrosine phosphorylation|regulation of cell adhesion|neuron differentiation|positive regulation of cell migration|membrane protein proteolysis|positive regulation of cell adhesion mediated by integrin|ureter maturation|neuron maturation|positive regulation of cell size|positive regulation of transcription, DNA-templated|response to pain|enteric nervous system development|regulation of axonogenesis|innervation|Peyer's patch morphogenesis|cellular response to retinoic acid|positive regulation of metanephric glomerulus development|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|calcium ion binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.7,4.74,10,0,0,-0.6,3.37,-3.37,0.387,0,0,-1.8,0.5
ENSMUSG00000060904,ARL1,ADP-ribosylation factor-like 1,intracellular|cytoplasm|Golgi apparatus|trans-Golgi network|membrane|extracellular vesicular exosome|,"GTP catabolic process|Golgi organization|small GTPase mediated signal transduction|toxin metabolic process|activation of phospholipase D activity|protein localization to Golgi apparatus|retrograde transport, endosome to Golgi|Golgi vesicle transport|",nucleotide binding|GTPase activity|GTP binding|enzyme activator activity|protein domain specific binding|metal ion binding|,10,-0.1,0.114,10,-0.5,4.73,-0.4,3.34,-3.34,0.389,0,0,-1.5,0.7
ENSMUSG00000039358,DRD5,dopamine receptor D5,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|dendrite|brush border membrane|brush border membrane|neuronal cell body|dendritic spine|,"synaptic transmission, dopaminergic|response to amphetamine|regulation of systemic arterial blood pressure by vasopressin|norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure|negative regulation of protein kinase activity|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|dopamine receptor signaling pathway|dopamine receptor signaling pathway|synaptic transmission|mating behavior|associative learning|visual learning|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|transmission of nerve impulse|negative regulation of cell migration|positive regulation of cAMP biosynthetic process|negative regulation of NAD(P)H oxidase activity|wound healing|response to cocaine|positive regulation of adenylate cyclase activity|negative regulation of blood pressure|negative regulation of blood pressure|regulation of female receptivity|sensitization|regulation of long-term neuronal synaptic plasticity|long term synaptic depression|cellular response to catecholamine stimulus|reactive oxygen species metabolic process|","dopamine neurotransmitter receptor activity, coupled via Gs|dopamine neurotransmitter receptor activity, coupled via Gs|dopamine neurotransmitter receptor activity, coupled via Gs|G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|dopamine neurotransmitter receptor activity|drug binding|dopamine binding|",10,-0.4,3.04,10,0.2,0.993,-0.4,3.32,-3.32,0.391,0,0,-1.5,0.7
ENSMUSG00000069516,LYZ2,lysozyme 2,Golgi cis cisterna|extracellular region|extracellular space|cytoplasm|endoplasmic reticulum lumen|Golgi stack|microvillus|trans-Golgi network transport vesicle|secretory granule|rough endoplasmic reticulum lumen|extracellular vesicular exosome|,metabolic process|cell wall macromolecule catabolic process|cytolysis|defense response to bacterium|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|,"lysozyme activity|lysozyme activity|catalytic activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|identical protein binding|",10,0.2,0.309,10,0.5,3.62,0.4,3.3,3.3,0.392,0,0,-0.5,1.5
ENSMUSG00000052776,OAS1A,2'-5' oligoadenylate synthetase 1A,nucleus|cytoplasm|,negative regulation of viral process|,2'-5'-oligoadenylate synthetase activity|2'-5'-oligoadenylate synthetase activity|double-stranded RNA binding|double-stranded RNA binding|protein binding|zinc ion binding|,10,-0.4,2.86,10,-0.4,0.634,-0.4,3.3,-3.3,0.392,0,0,-1.3,0.3
ENSMUSG00000076441,ASS1,argininosuccinate synthetase 1,nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|lysosome|endoplasmic reticulum|neuron projection|neuronal cell body|perikaryon|extracellular vesicular exosome|cell body fiber|,urea cycle|citrulline metabolic process|argininosuccinate metabolic process|arginine biosynthetic process|aspartate metabolic process|cellular amino acid biosynthetic process|response to zinc ion|response to mycotoxin|positive regulation of nitric oxide biosynthetic process|response to glucocorticoid|cellular response to laminar fluid shear stress|negative regulation of leukocyte cell-cell adhesion|,nucleotide binding|argininosuccinate synthase activity|ATP binding|toxic substance binding|amino acid binding|ligase activity|poly(A) RNA binding|,10,-0.7,5.57,10,-0.1,0.123,-0.6,3.3,-3.3,0.392,0,0,-2,0.5
ENSMUSG00000028991,MTOR,mechanistic target of rapamycin (serine/threonine kinase),nucleus|nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|lysosome|lysosomal membrane|endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|endomembrane system|membrane|PML body|dendrite|TORC1 complex|TORC2 complex|neuronal cell body|mTOR-FKBP12-rapamycin complex|,positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|regulation of glycogen biosynthetic process|regulation of carbohydrate metabolic process|protein phosphorylation|response to stress|germ cell development|negative regulation of autophagy|positive regulation of lamellipodium assembly|positive regulation of gene expression|positive regulation of myotube differentiation|cell growth|negative regulation of macroautophagy|phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|cell projection organization|cell projection organization|positive regulation of actin filament polymerization|positive regulation of actin filament polymerization|ruffle organization|cellular response to nutrient levels|TOR signaling|regulation of fatty acid beta-oxidation|regulation of response to food|regulation of Rac GTPase activity|response to insulin|regulation of actin cytoskeleton organization|response to amino acid|response to amino acid|regulation of carbohydrate utilization|positive regulation of translation|negative regulation of cell size|negative regulation of cell size|regulation of protein kinase activity|positive regulation of transcription from RNA polymerase III promoter|protein autophosphorylation|positive regulation of lipid biosynthetic process|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of stress fiber assembly|negative regulation of NFAT protein import into nucleus|positive regulation of protein kinase B signaling|cellular response to hypoxia|,"nucleotide binding|RNA polymerase III type 1 promoter DNA binding|RNA polymerase III type 2 promoter DNA binding|RNA polymerase III type 3 promoter DNA binding|TFIIIC-class transcription factor binding|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|drug binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|protein domain specific binding|ribosome binding|phosphoprotein binding|",10,1.1,5.09,10,0.2,0.598,0.6,3.28,3.28,0.393,0,0,-0.7,2
ENSMUSG00000039728,SLC6A5,"solute carrier family 6 (neurotransmitter transporter, glycine), member 5",plasma membrane|membrane|integral component of membrane|,"transport|neurotransmitter transport|glycine transport|sodium ion transmembrane transport|glycine import|synaptic transmission, glycinergic|L-alpha-amino acid transmembrane transport|",neurotransmitter:sodium symporter activity|glycine transmembrane transporter activity|symporter activity|glycine:sodium symporter activity|,10,-0.3,1.76,10,-0.3,1.73,-0.3,3.26,-3.26,0.395,0,0,-1.3,0.7
ENSMUSG00000062070,PGK1,phosphoglycerate kinase 1,cytosol|membrane|extracellular vesicular exosome|,carbohydrate metabolic process|gluconeogenesis|glycolytic process|glycolytic process|phosphorylation|,phosphoglycerate kinase activity|phosphoglycerate kinase activity|ATP binding|ADP binding|,4,0.8,2.57,5,-0.8,4.49,-0.7,3.25,-3.25,0.395,0,0,-2,1.3
ENSMUSG00000026260,NDUFA10,NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10,mitochondrion|mitochondrial respiratory chain complex I|respiratory chain|,nucleobase-containing compound metabolic process|transport|biological_process|oxidation-reduction process|,molecular_function|ATP binding|nucleoside kinase activity|,10,0.2,1.76,9,0.8,3.19,0.4,3.25,3.25,0.395,0,0,-0.4,1.8
ENSMUSG00000026959,GRIN1,"glutamate receptor, ionotropic, NMDA1 (zeta 1)",cytoplasm|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|synaptic vesicle|cell surface|postsynaptic density|postsynaptic density|membrane|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|dendrite|dendrite|growth cone|dendrite membrane|synaptic cleft|terminal bouton|dendritic spine|dendritic spine|synapse|synapse|postsynaptic membrane|excitatory synapse|neuronal postsynaptic density|,"conditioned taste aversion|startle response|suckling behavior|response to amphetamine|response to amphetamine|transport|ion transport|cation transport|cation transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|synaptic transmission|respiratory gaseous exchange|learning or memory|learning|memory|long-term memory|associative learning|adult locomotory behavior|olfactory learning|visual learning|visual learning|regulation of cell communication|positive regulation of cell death|propylene metabolic process|sensory perception of pain|pons maturation|cerebral cortex development|ion transmembrane transport|regulation of ion transmembrane transport|social behavior|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|regulation of membrane potential|regulation of membrane potential|regulation of membrane potential|positive regulation of apoptotic process|response to morphine|regulation of neuron apoptotic process|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|regulation of respiratory gaseous exchange|response to ethanol|positive regulation of transcription from RNA polymerase II promoter|regulation of synaptic plasticity|regulation of neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|rhythmic process|regulation of dendrite morphogenesis|regulation of axonogenesis|neuromuscular process|protein tetramerization|regulation of synapse assembly|calcium ion homeostasis|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|prepulse inhibition|male mating behavior|calcium ion transmembrane transport|positive regulation of excitatory postsynaptic membrane potential|",receptor activity|ionotropic glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|receptor binding|receptor binding|transporter activity|ion channel activity|extracellular-glutamate-gated ion channel activity|cation channel activity|calcium channel activity|calcium channel activity|calcium channel activity|calcium ion binding|protein binding|calmodulin binding|glycine binding|glycine binding|glutamate binding|enzyme binding|voltage-gated cation channel activity|glutamate receptor binding|neurotransmitter binding|protein heterodimerization activity|protein dimerization activity|,10,0.7,6.24,10,-0.2,0.484,0.7,3.24,3.24,0.396,0,0,-0.4,1.8
ENSMUSG00000042105,INPP5F,inositol polyphosphate-5-phosphatase F,intracellular|,cardiac muscle hypertrophy in response to stress|phosphatidylinositol catabolic process|phosphatidylinositol-mediated signaling|regulation of protein kinase B signaling|,"molecular_function|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|phosphoric ester hydrolase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,-0.5,3.78,10,-0.1,0.583,-0.3,3.17,-3.17,0.401,0,0,-1.7,0.1
ENSMUSG00000028979,MASP2,mannan-binding lectin serine peptidase 2,extracellular region|extracellular vesicular exosome|,"complement activation, lectin pathway|complement activation, lectin pathway|immune system process|proteolysis|complement activation|complement activation, classical pathway|innate immune response|",complement component C4b binding|catalytic activity|serine-type endopeptidase activity|calcium ion binding|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|metal ion binding|calcium-dependent protein binding|,9,-0.4,4.94,10,0,0,-0.3,3.15,-3.15,0.402,0,0,-1.6,0.4
ENSMUSG00000027895,KCNC4,"potassium voltage gated channel, Shaw-related subfamily, member 4",voltage-gated potassium channel complex|membrane|integral component of membrane|neuromuscular junction|axon terminus|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|regulation of neurotransmitter secretion|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.3,0.907,10,-0.2,2.41,-0.2,3.09,-3.09,0.406,0,0,-1.4,0.5
ENSMUSG00000027318,ADAM33,a disintegrin and metallopeptidase domain 33,membrane|integral component of membrane|,proteolysis|integrin-mediated signaling pathway|regulation of cytokine biosynthetic process|regulation of cell proliferation|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.3,0.78,10,0.4,2.53,0.3,3.08,3.08,0.407,0,0,-0.6,1.4
ENSMUSG00000022672,PRKDC,"protein kinase, DNA activated, catalytic polypeptide",intracellular|nucleus|nucleus|transcription factor complex|DNA-dependent protein kinase-DNA ligase 4 complex|membrane|nonhomologous end joining complex|,telomere maintenance|somitogenesis|negative regulation of protein phosphorylation|B cell lineage commitment|pro-B cell differentiation|T cell lineage commitment|DNA repair|double-strand break repair|double-strand break repair via nonhomologous end joining|cellular response to DNA damage stimulus|brain development|heart development|intrinsic apoptotic signaling pathway in response to DNA damage|response to gamma radiation|phosphorylation|peptidyl-serine phosphorylation|lymphocyte differentiation|protein destabilization|cellular response to insulin stimulus|T cell differentiation in thymus|immunoglobulin V(D)J recombination|T cell receptor V(D)J recombination|ectopic germ cell programmed cell death|regulation of circadian rhythm|positive regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|signal transduction involved in mitotic G1 DNA damage checkpoint|,"nucleotide binding|DNA binding|protein serine/threonine kinase activity|DNA-dependent protein kinase activity|protein binding|ATP binding|transcription factor binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|enzyme binding|poly(A) RNA binding|",10,0.3,1.57,10,0.4,1.87,0.3,3.08,3.08,0.407,0,0,-0.4,1.8
ENSMUSG00000027107,CHRNA1,"cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|cell surface|cell surface|membrane|integral component of membrane|cell junction|neuromuscular junction|neuromuscular junction|synapse|postsynaptic membrane|,skeletal muscle contraction|transport|ion transport|cation transport|neuromuscular synaptic transmission|neuromuscular junction development|neuronal action potential|ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|muscle cell cellular homeostasis|skeletal muscle tissue growth|musculoskeletal movement|neuromuscular process|neuron cellular homeostasis|,acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|acetylcholine receptor activity|acetylcholine binding|,10,-0.6,5.57,10,0,0,-0.4,3.06,-3.06,0.409,0,0,-1.6,0.3
ENSMUSG00000026228,HTR2B,5-hydroxytryptamine (serotonin) receptor 2B,intracellular|cytoplasm|cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|neuron projection|synapse|,neural crest cell migration|positive regulation of cytokine production|positive regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|G-protein coupled receptor internalization|heart morphogenesis|cardiac muscle hypertrophy|cGMP biosynthetic process|cellular calcium ion homeostasis|smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|activation of phospholipase C activity|protein kinase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating serotonin receptor signaling pathway|serotonin receptor signaling pathway|serotonin receptor signaling pathway|heart development|behavior|positive regulation of cell proliferation|negative regulation of autophagy|positive regulation of phosphatidylinositol biosynthetic process|neural crest cell differentiation|phosphatidylinositol 3-kinase signaling|intestine smooth muscle contraction|phosphorylation|calcium-mediated signaling|positive regulation of Ras GTPase activity|vasoconstriction|response to drug|response to drug|negative regulation of apoptotic process|positive regulation of MAP kinase activity|embryonic morphogenesis|positive regulation of cytokine secretion|regulation of behavior|regulation of behavior|positive regulation of nitric-oxide synthase activity|release of sequestered calcium ion into cytosol|positive regulation of cell division|negative regulation of cell death|ERK1 and ERK2 cascade|ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|protein kinase C signaling|cellular response to temperature stimulus|,G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|serotonin receptor activity|serotonin receptor activity|Ras GTPase activator activity|drug binding|drug binding|serotonin binding|serotonin binding|,10,-0.2,0.506,10,0.8,4.83,0.4,3.03,3.03,0.411,0,0,-0.7,1.9
ENSMUSG00000026277,STK25,serine/threonine kinase 25 (yeast),cytoplasm|Golgi apparatus|,protein phosphorylation|protein phosphorylation|establishment or maintenance of cell polarity|phosphorylation|signal transduction by phosphorylation|positive regulation of axonogenesis|positive regulation of axonogenesis|Golgi localization|Golgi localization|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|metal ion binding|",10,0.1,0.0357,10,-0.7,5.83,-0.5,3.01,-3.01,0.412,0,0,-1.9,0.2
ENSMUSG00000021279,CDC42BPB,CDC42 binding protein kinase beta,cytoplasm|plasma membrane|membrane|cell junction|actomyosin|extracellular vesicular exosome|,protein phosphorylation|phosphorylation|cell migration|actin cytoskeleton organization|actomyosin structure organization|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rho GTPase binding|metal ion binding|",10,0.9,5.05,10,-0.2,0.18,0.3,2.91,2.91,0.42,0,0,-0.2,1.9
ENSMUSG00000062937,MTAP,methylthioadenosine phosphorylase,nucleus|cytoplasm|extracellular vesicular exosome|,purine ribonucleoside salvage|biological_process|nucleoside metabolic process|,"catalytic activity|phosphorylase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring pentosyl groups|S-methyl-5-thioadenosine phosphorylase activity|",10,0.2,0.863,10,0.5,2.95,0.2,2.91,2.91,0.42,0,0,-0.6,1.5
ENSMUSG00000028226,MMP16,matrix metallopeptidase 16,plasma membrane|membrane|integral component of membrane|extracellular matrix|,ossification|endochondral ossification|proteolysis|collagen catabolic process|collagen catabolic process|chondrocyte proliferation|embryonic cranial skeleton morphogenesis|bone development|craniofacial suture morphogenesis|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.6,3.32,10,0.2,0.169,0.3,2.86,2.86,0.423,0,0,-0.6,1.7
ENSMUSG00000056201,CFL1,"cofilin 1, non-muscle",extracellular space|intracellular|nucleus|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|cell-cell junction|actin cytoskeleton|membrane|membrane|lamellipodium|cortical actin cytoskeleton|cell leading edge|cell projection|extracellular vesicular exosome|,mitotic cytokinesis|neural crest cell migration|neural fold formation|protein phosphorylation|protein import into nucleus|cellular component movement|cytoskeleton organization|actin filament organization|regulation of cell morphogenesis|establishment of cell polarity|cell projection organization|actin filament depolymerization|positive regulation of actin filament depolymerization|response to amino acid|negative regulation of cell size|,actin binding|,5,0.8,2.61,6,0.5,0.713,0.6,2.86,2.86,0.423,0,0,-0.3,2
ENSMUSG00000020022,NDUFA12,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12",cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|respiratory chain|,transport|response to oxidative stress|oxidation-reduction process|,molecular_function|NADH dehydrogenase (ubiquinone) activity|electron carrier activity|,10,0.3,1.22,10,-0.5,4.89,-0.5,2.8,-2.8,0.428,0,0,-1.5,0.7
ENSMUSG00000033105,LSS,lanosterol synthase,endoplasmic reticulum|lipid particle|membrane|membrane|intracellular membrane-bounded organelle|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|sterol metabolic process|,lanosterol synthase activity|catalytic activity|isomerase activity|intramolecular transferase activity|,10,0.1,0.382,10,0.8,3.33,0.5,2.79,2.79,0.429,0,0,-0.2,1.8
ENSMUSG00000034354,MTMR3,myotubularin related protein 3,nucleus|cytoplasm|membrane|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|phosphatidylinositol dephosphorylation|,phosphatidylinositol-3-phosphatase activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|,9,1.1,5.51,9,0.1,0.0408,0.6,2.79,2.79,0.429,0,0,0,2
ENSMUSG00000020182,DDC,dopa decarboxylase,cytoplasm|cytoplasm|synaptic vesicle|axon|neuronal cell body|extracellular vesicular exosome|,cellular amino acid metabolic process|response to toxic substance|synaptic vesicle amine transport|carboxylic acid metabolic process|dopamine biosynthetic process|catecholamine biosynthetic process|serotonin biosynthetic process|,catalytic activity|aromatic-L-amino-acid decarboxylase activity|aromatic-L-amino-acid decarboxylase activity|amino acid binding|lyase activity|carboxy-lyase activity|protein domain specific binding|pyridoxal phosphate binding|,10,0.1,0.0681,10,0.4,3.99,0.3,2.78,2.78,0.43,0,0,-0.3,1.5
ENSMUSG00000017405,NEK8,NIMA (never in mitosis gene a)-related expressed kinase 8,cytoplasm|cytoskeleton|cilium|cell projection|primary cilium|,protein phosphorylation|organ morphogenesis|phosphorylation|regulation of hippo signaling|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.4,4.82,10,-0.1,0.391,0.3,2.77,2.77,0.431,0,0,-0.7,1.4
ENSMUSG00000043501,LGALS2,"lectin, galactose-binding, soluble 2",None,None,galactoside binding|carbohydrate binding|,10,0.3,2.74,10,0.3,0.164,0.3,2.75,2.75,0.432,0,0,-0.6,1.6
ENSMUSG00000001323,SRR,serine racemase,cytoplasm|plasma membrane|neuronal cell body|apical part of cell|,cellular amino acid metabolic process|L-serine metabolic process|L-serine metabolic process|metabolic process|serine family amino acid metabolic process|pyruvate biosynthetic process|protein homotetramerization|D-serine metabolic process|D-serine biosynthetic process|D-serine biosynthetic process|,nucleotide binding|magnesium ion binding|catalytic activity|L-serine ammonia-lyase activity|calcium ion binding|protein binding|ATP binding|ATP binding|D-serine ammonia-lyase activity|glycine binding|lyase activity|isomerase activity|threonine racemase activity|PDZ domain binding|pyridoxal phosphate binding|pyridoxal phosphate binding|serine racemase activity|serine racemase activity|protein homodimerization activity|protein homodimerization activity|metal ion binding|,9,0.3,1.67,9,-0.3,2,0.4,2.74,2.74,0.433,0,0,-0.7,1.7
ENSMUSG00000093931,AMY2A3,amylase 2a3,None,biological_process|,None,9,-0.8,5.39,8,0,0,-0.8,2.74,-2.74,0.433,0,0,-1.6,1.9
ENSMUSG00000096770,AMY2A4,amylase 2a4,None,biological_process|,None,9,-0.8,5.39,8,0,0,-0.8,2.74,-2.74,0.433,0,0,-1.6,1.9
ENSMUSG00000020444,GUK1,guanylate kinase 1,cytosol|,purine nucleotide metabolic process|purine nucleotide metabolic process|dGDP biosynthetic process|phosphorylation|GDP-mannose metabolic process|glycoprotein transport|ATP metabolic process|GMP metabolic process|dGMP metabolic process|dATP metabolic process|GDP biosynthetic process|nucleotide phosphorylation|nucleotide phosphorylation|,nucleotide binding|guanylate kinase activity|guanylate kinase activity|ATP binding|kinase activity|transferase activity|,7,1,4.83,7,-1,4.02,0.9,2.73,2.73,0.434,0,0,-1.6,2
ENSMUSG00000028738,TAS1R2,"taste receptor, type 1, member 2",plasma membrane|membrane|integral component of membrane|receptor complex|,detection of chemical stimulus involved in sensory perception of sweet taste|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytokinesis|response to stimulus|sensory perception of taste|sensory perception of sweet taste|sensory perception of sweet taste|,signal transducer activity|G-protein coupled receptor activity|protein binding|taste receptor activity|taste receptor activity|sweet taste receptor activity|,9,-0.4,3.59,9,-0.1,0.271,-0.3,2.72,-2.72,0.435,0,0,-1.6,0.4
ENSMUSG00000047804,AKAP10,A kinase (PRKA) anchor protein 10,cytoplasm|mitochondrion|plasma membrane|membrane|,protein localization|protein localization|termination of G-protein coupled receptor signaling pathway|,protein kinase A binding|,10,-0.4,2.41,10,-0.2,0.952,-0.3,2.72,-2.72,0.435,0,0,-1.6,0.4
ENSMUSG00000030854,PTPN5,"protein tyrosine phosphatase, non-receptor type 5",cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphotyrosine binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,9,0.8,0.839,9,0.4,2.17,0.7,2.72,2.72,0.435,0,0,-0.2,1.8
ENSMUSG00000028273,PDLIM5,PDZ and LIM domain 5,cytoplasm|cytosol|plasma membrane|postsynaptic density|actin cytoskeleton|membrane|Z disc|cell junction|neuron projection|synapse|postsynaptic membrane|,regulation of synapse assembly|regulation of dendritic spine morphogenesis|,actin binding|protein kinase C binding|protein binding|zinc ion binding|actinin binding|metal ion binding|protein N-terminus binding|,10,1,4.35,10,-0.2,1.31,-0.3,2.7,-2.7,0.437,0,0,-1.4,1.9
ENSMUSG00000032571,PIK3R4,"phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150",endosome|late endosome|axoneme|membrane|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0.5,3.58,9,0.1,0.0726,0.4,2.7,2.7,0.437,0,0,-0.6,1.6
ENSMUSG00000029597,SDS,serine dehydratase,cytoplasm|mitochondrion|,gluconeogenesis|cellular amino acid metabolic process|L-serine catabolic process|pyruvate biosynthetic process|,L-serine ammonia-lyase activity|L-threonine ammonia-lyase activity|lyase activity|pyridoxal phosphate binding|protein homodimerization activity|protein dimerization activity|,9,-1,2.34,9,-0.7,1.26,-0.7,2.69,-2.69,0.438,0,0,-2,0.2
ENSMUSG00000044303,CDKN2A,cyclin-dependent kinase inhibitor 2A,granular component|nucleus|nucleoplasm|nucleoplasm|nucleolus|nucleolus|cytoplasm|cytoplasm|mitochondrion|nuclear body|senescence-associated heterochromatin focus|protein complex|,"cell cycle checkpoint|regulation of cyclin-dependent protein serine/threonine kinase activity|G1/S transition of mitotic cell cycle|protein polyubiquitination|negative regulation of cell-matrix adhesion|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|negative regulation of protein kinase activity|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell cycle|cell cycle arrest|cell cycle arrest|aging|cell aging|negative regulation of cell proliferation|epidermis development|apoptotic mitochondrial changes|rRNA transcription|response to organonitrogen compound|regulation of G2/M transition of mitotic cell cycle|regulation of gene expression|response to organic cyclic compound|negative regulation of cell growth|negative regulation of cell growth|negative regulation of B cell proliferation|regulation of protein stability|protein destabilization|negative regulation of NF-kappaB transcription factor activity|negative regulation of immature T cell proliferation in thymus|positive regulation of protein sumoylation|negative regulation of mammary gland epithelial cell proliferation|positive regulation of smooth muscle cell apoptotic process|somatic stem cell maintenance|senescence-associated heterochromatin focus assembly|negative regulation of phosphorylation|response to drug|positive regulation of apoptotic process|positive regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of nucleocytoplasmic transport|regulation of protein export from nucleus|somatic stem cell division|protein stabilization|positive regulation of sequence-specific DNA binding transcription factor activity|negative regulation of ubiquitin-protein transferase activity|positive regulation of apoptotic process involved in mammary gland involution|cellular response to hydrogen peroxide|protein K63-linked ubiquitination|positive regulation of cell cycle arrest|cellular senescence|cellular senescence|replicative senescence|regulation of apoptotic DNA fragmentation|positive regulation of macrophage apoptotic process|positive regulation of cellular senescence|",p53 binding|DNA binding|sequence-specific DNA binding transcription factor activity|cyclin-dependent protein serine/threonine kinase inhibitor activity|cyclin-dependent protein serine/threonine kinase inhibitor activity|protein binding|transcription factor binding|protein kinase binding|poly(A) RNA binding|NF-kappaB binding|ubiquitin-protein transferase inhibitor activity|MDM2/MDM4 family protein binding|,10,0,0,10,0.8,5.7,0.5,2.68,2.68,0.439,0,0,0,1.9
ENSMUSG00000041939,MVK,mevalonate kinase,cytoplasm|peroxisome|cytosol|extracellular vesicular exosome|,"lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|metabolic process|steroid metabolic process|cholesterol metabolic process|isoprenoid biosynthetic process|sterol biosynthetic process|phosphorylation|negative regulation of translation|isopentenyl diphosphate biosynthetic process, mevalonate pathway|negative regulation of inflammatory response|","nucleotide binding|mRNA binding|mevalonate kinase activity|mevalonate kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|identical protein binding|",9,-1.2,3.91,9,0.4,2.92,-1.1,2.67,-2.67,0.439,0,0,-2,0.9
ENSMUSG00000025877,HK3,hexokinase 3,mitochondrion|cytosol|protein complex|,cellular glucose homeostasis|carbohydrate metabolic process|glycolytic process|metabolic process|phosphorylation|carbohydrate phosphorylation|carbohydrate phosphorylation|glucose 6-phosphate metabolic process|,"nucleotide binding|catalytic activity|glucokinase activity|hexokinase activity|ATP binding|fructokinase activity|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|mannokinase activity|enzyme binding|hormone binding|",10,1.4,5.42,10,0.2,0.409,1.4,2.66,2.66,0.44,0,0,-0.1,2
ENSMUSG00000023913,PLA2G7,"phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)",extracellular region|extracellular space|cytoplasm|low-density lipoprotein particle|,lipid metabolic process|inflammatory response|lipid catabolic process|low-density lipoprotein particle remodeling|lipid oxidation|plasma lipoprotein particle oxidation|positive regulation of monocyte chemotaxis|,1-alkyl-2-acetylglycerophosphocholine esterase activity|phospholipid binding|hydrolase activity|calcium-independent phospholipase A2 activity|,10,-0.4,2.18,10,-0.2,0.992,-0.3,2.66,-2.66,0.44,0,0,-1.3,0.8
ENSMUSG00000030934,OAT,ornithine aminotransferase,cytoplasm|mitochondrion|mitochondrion|,protein hexamerization|,catalytic activity|ornithine-oxo-acid transaminase activity|transaminase activity|transferase activity|pyridoxal phosphate binding|,10,-0.3,1.26,10,-0.6,1.96,-0.4,2.66,-2.66,0.44,0,0,-1.7,0.2
ENSMUSG00000056158,CAR10,carbonic anhydrase 10,cellular_component|,biological_process|,molecular_function|,10,0.5,4.72,10,-0.1,0.0685,0.4,2.64,2.64,0.442,0,0,-0.4,1.5
ENSMUSG00000050783,HTR1F,5-hydroxytryptamine (serotonin) receptor 1F,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|serotonin receptor signaling pathway|serotonin receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|serotonin receptor activity|serotonin binding|,10,-0.6,5.22,10,0,0,-0.5,2.64,-2.64,0.442,0,0,-1.8,0.7
ENSMUSG00000034868,MYL12B,"myosin, light chain 12B, regulatory",stress fiber|myosin complex|myosin II complex|Z disc|protein complex|apical part of cell|extracellular vesicular exosome|,regulation of cell shape|,calcium ion binding|metal ion binding|,7,0.7,4.87,7,-0.6,1.55,0.7,2.62,2.62,0.444,0,0,-1,2
ENSMUSG00000038286,BPHL,"biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)",cytoplasm|mitochondrion|extracellular vesicular exosome|,biological_process|,molecular_function|nuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,-0.5,0.976,10,-0.4,1.93,-0.4,2.61,-2.61,0.445,0,0,-1.6,0.8
ENSMUSG00000000532,ACVR1B,"activin A receptor, type 1B",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,"G1/S transition of mitotic cell cycle|in utero embryonic development|hair follicle development|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|signal transduction|cell surface receptor signaling pathway|transmembrane receptor protein serine/threonine kinase signaling pathway|mesoderm development|embryo development|regulation of signal transduction|positive regulation of pathway-restricted SMAD protein phosphorylation|phosphorylation|peptidyl-threonine phosphorylation|peptidyl-threonine phosphorylation|signal transduction by phosphorylation|negative regulation of cell growth|activin receptor signaling pathway|activin receptor signaling pathway|positive regulation of activin receptor signaling pathway|intracellular signal transduction|nodal signaling pathway|positive regulation of erythrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|extrinsic apoptotic signaling pathway|positive regulation of trophoblast cell migration|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|protein binding|ATP binding|kinase activity|activin receptor activity, type I|transferase activity|transferase activity, transferring phosphorus-containing groups|activin-activated receptor activity|growth factor binding|inhibin binding|SMAD binding|metal ion binding|activin binding|activin binding|",10,-0.1,0.232,10,0.5,5.04,0.5,2.6,2.6,0.445,0,0,-0.4,1.7
ENSMUSG00000037003,TENC1,tensin like C1 domain-containing phosphatase,plasma membrane|focal adhesion|membrane|cell junction|,kidney development|negative regulation of cell proliferation|response to muscle activity|cellular homeostasis|collagen metabolic process|multicellular organism growth|intracellular signal transduction|multicellular organismal homeostasis|,"phosphoprotein phosphatase activity|receptor binding|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|protein kinase binding|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|metal ion binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,-0.3,1.72,10,-0.2,1.15,-0.3,2.59,-2.59,0.446,0,0,-1.5,0.6
ENSMUSG00000016319,SLC25A5,"solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|membrane|membrane|integral component of membrane|mitochondrial nucleoid|extracellular vesicular exosome|MMXD complex|,transport|chromosome segregation|positive regulation of cell proliferation|transmembrane transport|negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|,transporter activity|poly(A) RNA binding|,10,0.3,0.919,9,-0.6,3.66,-0.3,2.59,-2.59,0.446,0,0,-1.7,0.9
ENSMUSG00000022033,PBK,PDZ binding kinase,cellular_component|,negative regulation of protein phosphorylation|protein phosphorylation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of stress-activated MAPK cascade|cellular response to UV|negative regulation of inflammatory response|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,3.15,10,0.1,0.2,0.4,2.58,2.58,0.448,0,0,-0.6,1.5
ENSMUSG00000031303,MAP3K15,mitogen-activated protein kinase kinase kinase 15,None,MAPK cascade|activation of MAPKK activity|protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.6,2.17,10,0.2,1.3,0.3,2.56,2.56,0.449,0,0,-1.4,1.3
ENSMUSG00000035268,PKIG,"protein kinase inhibitor, gamma",cellular_component|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of protein kinase activity|signal transduction|negative regulation of protein import into nucleus|negative regulation of protein serine/threonine kinase activity|negative regulation of protein serine/threonine kinase activity|,protein kinase inhibitor activity|cAMP-dependent protein kinase inhibitor activity|cAMP-dependent protein kinase inhibitor activity|,10,0.4,3.2,10,0.1,0.0543,0.3,2.56,2.56,0.449,0,0,-0.6,1.5
ENSMUSG00000033102,CDC14B,CDC14 cell division cycle 14B,nucleus|nucleoplasm|nucleolus|nuclear membrane|,DNA repair|protein dephosphorylation|cellular response to DNA damage stimulus|dephosphorylation|G2 DNA damage checkpoint|peptidyl-tyrosine dephosphorylation|activation of anaphase-promoting complex activity|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,9,1.1,3.2,9,0.4,1.16,0.6,2.56,2.56,0.449,0,0,0,2
ENSMUSG00000005763,CD247,CD247 antigen,cytoplasm|plasma membrane|membrane|integral component of membrane|T cell receptor complex|alpha-beta T cell receptor complex|,cell surface receptor signaling pathway|T cell receptor signaling pathway|,transmembrane signaling receptor activity|protein binding|identical protein binding|,9,-0.2,0.626,9,-0.3,2.4,-0.3,2.56,-2.56,0.449,0,0,-1.5,0.7
ENSMUSG00000040021,LATS1,large tumor suppressor,spindle pole|intracellular|cytoplasm|cytoskeleton|,G2/M transition of mitotic cell cycle|sister chromatid segregation|protein phosphorylation|cell cycle|mitotic nuclear division|hormone-mediated signaling pathway|phosphorylation|keratinocyte differentiation|regulation of actin filament polymerization|positive regulation of peptidyl-serine phosphorylation|cellular protein localization|hippo signaling|hippo signaling|regulation of protein complex assembly|negative regulation of cyclin-dependent protein serine/threonine kinase activity|cytoplasmic sequestering of protein|cell division|negative regulation of canonical Wnt signaling pathway|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|metal ion binding|",9,-0.2,0.336,9,0.4,3.07,0.3,2.54,2.54,0.451,0,0,-1.3,1.4
ENSMUSG00000024177,NME4,NME/NM23 nucleoside diphosphate kinase 4,mitochondrion|mitochondrion|,nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|nucleotide metabolic process|phosphorylation|,nucleotide binding|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|protein complex binding|metal ion binding|,10,1.4,5.76,10,0.1,0.066,1.4,2.52,2.52,0.453,0,0,-0.1,2
ENSMUSG00000026473,GLUL,glutamate-ammonia ligase (glutamine synthetase),nucleus|cytoplasm|cytoplasm|mitochondrion|rough endoplasmic reticulum|cell projection|neuron projection|perikaryon|intracellular membrane-bounded organelle|protein complex|axon terminus|cell body|extracellular vesicular exosome|glial cell projection|,"glutamate metabolic process|glutamine biosynthetic process|nitrogen compound metabolic process|cell proliferation|cellular response to starvation|response to glucose|ammonia assimilation cycle|positive regulation of insulin secretion|positive regulation of epithelial cell proliferation|protein homooligomerization|positive regulation of synaptic transmission, glutamatergic|",nucleotide binding|magnesium ion binding|catalytic activity|glutamate decarboxylase activity|glutamate-ammonia ligase activity|protein binding|ATP binding|glutamate binding|lyase activity|ligase activity|manganese ion binding|identical protein binding|dynein light chain binding|,9,-0.3,0.988,9,-0.7,2.22,-0.3,2.49,-2.49,0.456,0,0,-1.8,1.1
ENSMUSG00000034855,CXCL10,chemokine (C-X-C motif) ligand 10,extracellular region|extracellular space|extracellular space|cell|external side of plasma membrane|,positive regulation of leukocyte chemotaxis|chemotaxis|inflammatory response|immune response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cell proliferation|protein secretion|T cell chemotaxis|negative regulation of angiogenesis|positive regulation of cell migration|positive regulation of cAMP metabolic process|regulation of cell proliferation|positive regulation of cAMP-mediated signaling|positive regulation of release of sequestered calcium ion into cytosol|defense response to virus|cell chemotaxis|chemokine-mediated signaling pathway|cellular response to lipopolysaccharide|positive regulation of T cell migration|,cytokine activity|chemokine activity|heparin binding|CXCR3 chemokine receptor binding|,10,-0.2,0.813,10,-0.3,1.98,-0.2,2.49,-2.49,0.456,0,0,-1.6,0.5
ENSMUSG00000028076,CD1D1,CD1d1 antigen,cytoplasm|lysosome|endosome|early endosome|late endosome|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,"positive regulation of T cell mediated cytotoxicity|immune system process|immune response|antigen processing and presentation|positive regulation of T cell proliferation|positive regulation of macrophage activation|positive thymic T cell selection|positive regulation of interferon-gamma biosynthetic process|positive regulation of interleukin-2 biosynthetic process|innate immune response|positive regulation of interleukin-4 biosynthetic process|positive regulation of interleukin-4 biosynthetic process|antigen processing and presentation, endogenous lipid antigen via MHC class Ib|antigen processing and presentation, exogenous lipid antigen via MHC class Ib|regulation of immune response|positive regulation of NK T cell activation|positive regulation of NK T cell differentiation|",protein binding|lipid antigen binding|endogenous lipid antigen binding|exogenous lipid antigen binding|histone binding|T cell receptor binding|cell adhesion molecule binding|,10,-0.2,1.32,10,-0.5,2.37,-0.3,2.47,-2.47,0.457,0,0,-1.6,1
ENSMUSG00000026575,NME7,NME/NM23 family member 7,intracellular|cell|centrosome|centrosome|cilium|ciliary basal body|,epithelial cilium movement|nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|determination of left/right symmetry|brain development|nucleotide metabolic process|phosphorylation|intraciliary transport|ciliary receptor clustering involved in smoothened signaling pathway|left/right pattern formation|,nucleotide binding|molecular_function|nucleoside diphosphate kinase activity|ATP binding|kinase activity|transferase activity|metal ion binding|,10,0.2,1.3,10,0.2,1.34,0.2,2.46,2.46,0.458,0,0,-0.6,1.5
ENSMUSG00000005716,PVALB,parvalbumin,nucleus|cytoplasm|cytoplasm|axon|neuronal cell body|protein complex|extracellular vesicular exosome|,cytosolic calcium ion homeostasis|,calcium ion binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,0.5,2.19,10,-1.1,3.91,0.4,2.45,2.45,0.459,0,0,-1.9,1.1
ENSMUSG00000021940,PTPN20,"protein tyrosine phosphatase, non-receptor type 20",nucleus|cytoplasm|cytoskeleton|microtubule|,protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|,9,-0.2,0.543,9,-0.3,2.33,-0.3,2.42,-2.42,0.462,0,0,-1.6,0.7
ENSMUSG00000027896,SLC16A4,"solute carrier family 16 (monocarboxylic acid transporters), member 4",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,0.6,0.889,10,0.4,1.82,0.5,2.39,2.39,0.465,0,0,-0.6,1.6
ENSMUSG00000071424,GRID2,"glutamate receptor, ionotropic, delta 2",plasma membrane|ionotropic glutamate receptor complex|postsynaptic density|membrane|integral component of membrane|cell junction|dendritic spine|synapse|postsynaptic membrane|postsynaptic membrane|,"transport|ion transport|heterophilic cell-cell adhesion|regulation of neuron projection development|cerebellar granule cell differentiation|ion transmembrane transport|cellular protein localization|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|regulation of neuron apoptotic process|regulation of neuron apoptotic process|regulation of excitatory postsynaptic membrane potential|prepulse inhibition|",receptor activity|ionotropic glutamate receptor activity|transporter activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|PDZ domain binding|PDZ domain binding|scaffold protein binding|,9,-0.2,0.262,9,-0.3,2.39,-0.3,2.38,-2.38,0.466,0,0,-1.5,0.9
ENSMUSG00000011463,CPB1,carboxypeptidase B1 (tissue),cellular_component|,proteolysis|,carboxypeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,-0.1,0.0497,10,-0.7,4.46,-0.5,2.38,-2.38,0.466,0,0,-1.9,0.2
ENSMUSG00000020734,GRIN2C,"glutamate receptor, ionotropic, NMDA2C (epsilon 3)",plasma membrane|postsynaptic density|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|dendrite|synapse|postsynaptic membrane|,"transport|ion transport|cation transport|cation transport|protein localization|protein localization|response to wounding|directional locomotion|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|negative regulation of protein catabolic process|regulation of membrane potential|neuromuscular process controlling balance|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|",receptor activity|ionotropic glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|cation channel activity|cation channel activity|protein binding|PDZ domain binding|protein N-terminus binding|,10,0.1,0.16,10,-0.8,4.91,0.3,2.35,2.35,0.469,0,0,-2,0.8
ENSMUSG00000026407,CACNA1S,"calcium channel, voltage-dependent, L type, alpha 1S subunit",cytoplasm|plasma membrane|voltage-gated calcium channel complex|membrane|integral component of membrane|sarcoplasmic reticulum|T-tubule|T-tubule|I band|sarcolemma|,skeletal system development|extraocular skeletal muscle development|transport|ion transport|calcium ion transport|calcium ion transport|calcium ion transport|muscle contraction|muscle contraction|muscle contraction|striated muscle contraction|endoplasmic reticulum organization|skeletal muscle tissue development|myoblast fusion|neuromuscular junction development|regulation of ion transmembrane transport|skeletal muscle adaptation|skeletal muscle fiber development|skeletal muscle fiber development|muscle cell development|transmembrane transport|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|metal ion binding|,10,0.3,0.548,10,0.5,2.07,0.4,2.33,2.33,0.471,0,0,-0.7,1.7
ENSMUSG00000027406,IDH3B,isocitrate dehydrogenase 3 (NAD+) beta,nucleus|mitochondrion|mitochondrion|,tricarboxylic acid cycle|isocitrate metabolic process|2-oxoglutarate metabolic process|NADH metabolic process|oxidation-reduction process|,isocitrate dehydrogenase (NAD+) activity|oxidoreductase activity|,9,0.1,0.0563,9,-0.3,2.76,-0.3,2.23,-2.23,0.481,0,0,-1.7,0.7
ENSMUSG00000071714,CSF2RB2,"colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)",membrane|integral component of membrane|,cytokine-mediated signaling pathway|,cytokine receptor activity|,8,-0.3,2.45,8,0.6,2.82,-0.3,2.22,-2.22,0.482,0,0,-1,1.7
ENSMUSG00000030275,ETNK1,ethanolamine kinase 1,cytoplasm|membrane|,lipid metabolic process|phosphatidylethanolamine biosynthetic process|phospholipid biosynthetic process|phosphorylation|,"nucleotide binding|ethanolamine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,-0.6,3.76,8,0,0,-0.4,2.22,-2.22,0.482,0,0,-1.8,1.1
ENSMUSG00000036273,LRRK2,leucine-rich repeat kinase 2,extracellular space|intracellular|cytoplasm|mitochondrion|trans-Golgi network|cytosol|plasma membrane|synaptic vesicle|membrane|inclusion body|axon|dendrite|mitochondrial membrane|cytoplasmic side of mitochondrial outer membrane|dendrite cytoplasm|neuron projection|neuronal cell body|perikaryon|intracellular membrane-bounded organelle|membrane raft|synapse|extracellular vesicular exosome|,MAPK cascade|activation of MAPKK activity|activation of MAPK activity|positive regulation of protein phosphorylation|GTP catabolic process|protein phosphorylation|autophagy|response to oxidative stress|small GTPase mediated signal transduction|neuromuscular junction development|determination of adult lifespan|positive regulation of autophagy|positive regulation of autophagy|regulation of neuron maturation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|olfactory bulb development|tangential migration from the subventricular zone to the olfactory bulb|positive regulation of protein ubiquitination|negative regulation of protein binding|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of GTPase activity|regulation of kidney size|exploration behavior|regulation of locomotion|regulation of membrane potential|positive regulation of programmed cell death|positive regulation of GTPase activity|protein autophosphorylation|protein autophosphorylation|intracellular distribution of mitochondria|neuron projection morphogenesis|regulation of mitochondrial depolarization|positive regulation of dopamine receptor signaling pathway|regulation of dendritic spine morphogenesis|neuron death|regulation of neuron death|regulation of neuroblast proliferation|negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation|regulation of branching morphogenesis of a nerve|regulation of synaptic vesicle exocytosis|,"SNARE binding|nucleotide binding|glycoprotein binding|actin binding|GTPase activity|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|enzyme inhibitor activity|GTPase activator activity|protein binding|ATP binding|GTP binding|GTP binding|tubulin binding|kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rho GTPase binding|Rho GTPase binding|syntaxin-1 binding|clathrin binding|GTP-dependent protein kinase activity|GTP-dependent protein kinase activity|identical protein binding|identical protein binding|protein homodimerization activity|ion channel binding|protein kinase A binding|",10,0.2,1.67,10,0.3,0.73,0.3,2.21,2.21,0.483,0,0,-0.8,1.5
ENSMUSG00000036398,PPP1R11,"protein phosphatase 1, regulatory (inhibitor) subunit 11",cytoplasm|,negative regulation of catalytic activity|,protein phosphatase inhibitor activity|,8,-0.8,1.81,8,0.4,2.01,-0.6,2.2,-2.2,0.484,0,0,-1.7,1.4
ENSMUSG00000040428,PLEKHA4,"pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4",cellular_component|cytoplasm|membrane|,biological_process|,molecular_function|lipid binding|,9,-0.4,0.605,9,0.4,2.94,0.2,2.19,2.19,0.485,0,0,-1.1,1.5
ENSMUSG00000025792,SLC25A10,"solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10",intracellular|cell|nucleus|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial membrane|,transport|phosphate ion transport|mitochondrial transport|sulfate transport|thiosulfate transport|malate transport|succinate transport|phosphate ion transmembrane transport|transmembrane transport|transmembrane transport|succinate transmembrane transport|malate transmembrane transport|sulfate transmembrane transport|,phosphate ion transmembrane transporter activity|sulfate transmembrane transporter activity|thiosulfate transmembrane transporter activity|malate transmembrane transporter activity|succinate transmembrane transporter activity|secondary active transmembrane transporter activity|antiporter activity|,10,0.5,2.12,10,0.2,1.26,0.4,2.17,2.17,0.487,0,0,-1,1.5
ENSMUSG00000005320,FGFR4,fibroblast growth factor receptor 4,nucleus|cytoplasm|endosome|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|cell-cell junction|membrane|integral component of membrane|,organ induction|protein phosphorylation|positive regulation of cell proliferation|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|regulation of extracellular matrix disassembly|phosphorylation|cell migration|peptidyl-tyrosine phosphorylation|regulation of lipid metabolic process|lung development|glucose homeostasis|positive regulation of proteolysis|protein autophosphorylation|positive regulation of metalloenzyme activity|phosphate ion homeostasis|alveolar secondary septum development|positive regulation of ERK1 and ERK2 cascade|regulation of bile acid biosynthetic process|regulation of bile acid biosynthetic process|regulation of cholesterol homeostasis|positive regulation of DNA biosynthetic process|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|fibroblast growth factor-activated receptor activity|protein binding|ATP binding|heparin binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|fibroblast growth factor binding|",10,1.4,5.07,10,0.1,0.0879,1.4,2.14,2.14,0.49,0,0,-0.2,2
ENSMUSG00000020154,PTPRB,"protein tyrosine phosphatase, receptor type, B",membrane|integral component of membrane|receptor complex|,angiogenesis|angiogenesis|protein dephosphorylation|dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,10,-0.1,0.0482,10,0.7,5.18,0.7,2.13,2.13,0.491,0,0,-0.4,2
ENSMUSG00000041301,CFTR,cystic fibrosis transmembrane conductance regulator,intracellular|cytoplasm|endosome|early endosome|plasma membrane|microvillus|cell surface|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|cytoplasmic vesicle membrane|endoplasmic reticulum Sec complex|chloride channel complex|protein complex|extracellular vesicular exosome|,cholesterol biosynthetic process|transport|ion transport|chloride transport|chloride transport|water transport|bicarbonate transport|bicarbonate transport|iodide transport|cholesterol transport|transepithelial chloride transport|lung development|vasodilation|positive regulation of vasodilation|sperm capacitation|intracellular pH elevation|transmembrane transport|membrane hyperpolarization|cellular response to cAMP|chloride transmembrane transport|chloride transmembrane transport|positive regulation of voltage-gated chloride channel activity|,"nucleotide binding|chloride channel activity|channel-conductance-controlling ATPase activity|protein binding|ATP binding|bicarbonate transmembrane transporter activity|chloride transmembrane transporter activity|hydrolase activity|ATPase activity|chloride channel inhibitor activity|enzyme binding|PDZ domain binding|ATPase activity, coupled to transmembrane movement of substances|",10,0.7,3.73,10,-0.1,0.278,0.3,2.1,2.1,0.494,0,0,-0.4,1.9
ENSMUSG00000032051,FDX1,ferredoxin 1,mitochondrion|mitochondrion|mitochondrial crista|,lipid metabolic process|steroid biosynthetic process|transport|steroid metabolic process|cholesterol metabolic process|hormone biosynthetic process|regulation of catalytic activity|positive regulation of oxidoreductase activity|oxidation-reduction process|NADPH oxidation|,"iron ion binding|cholesterol monooxygenase (side-chain-cleaving) activity|electron carrier activity|NADPH-adrenodoxin reductase activity|enzyme binding|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,0.8,3.65,10,0,0,0.4,2.1,2.1,0.494,0,0,-0.5,1.9
ENSMUSG00000015290,UBL4,ubiquitin-like 4,cytoplasm|cytosol|BAT3 complex|,transport|tail-anchored membrane protein insertion into ER membrane|,None,10,-1.2,5.4,10,0,0,-1.2,2.09,-2.09,0.495,0,0,-2,0.2
ENSMUSG00000034664,ITGA2B,integrin alpha 2b,focal adhesion|integrin complex|external side of plasma membrane|cell surface|membrane|integral component of membrane|blood microparticle|,positive regulation of leukocyte migration|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|platelet aggregation|,identical protein binding|metal ion binding|extracellular matrix binding|fibrinogen binding|,10,-0.5,1.45,10,0.4,3.26,0.3,2.08,2.08,0.496,0,0,-1.2,1.5
ENSMUSG00000040435,PPP1R15A,"protein phosphatase 1, regulatory (inhibitor) subunit 15A",endoplasmic reticulum|,regulation of translation|apoptotic process|response to stress|endoplasmic reticulum unfolded protein response|,protein kinase binding|,9,-0.2,0.751,9,-0.3,1.53,-0.2,2.08,-2.08,0.496,0,0,-1.6,0.8
ENSMUSG00000036879,PHKB,phosphorylase kinase beta,plasma membrane|phosphorylase kinase complex|membrane|,carbohydrate metabolic process|polysaccharide metabolic process|glycogen metabolic process|protein phosphorylation|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|phosphorylase kinase activity|phosphorylase kinase activity|calmodulin binding|",10,0.4,1.54,9,-0.7,2.95,0.4,2.07,2.07,0.497,0,0,-1.7,1.2
ENSMUSG00000001333,SYNC,syncoilin,cytoplasm|cytosol|intermediate filament|Z disc|neuromuscular junction|sarcolemma|,intermediate filament-based process|,structural molecule activity|protein binding|,10,-0.3,1.28,10,0.4,2.97,0.3,2.06,2.06,0.498,0,0,-1.2,1.3
ENSMUSG00000000399,NDUFA9,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial respiratory chain complex I|mitochondrial matrix|mitochondrial membrane|respiratory chain|,transport|oxidation-reduction process|,NADH dehydrogenase activity|protein complex binding|,9,0.5,2.31,7,-0.6,1,0.5,2.05,2.05,0.499,0,0,-1.1,1.8
ENSMUSG00000039824,MYL6B,"myosin, light polypeptide 6B",myosin complex|unconventional myosin complex|,muscle contraction|skeletal muscle tissue development|muscle filament sliding|,motor activity|calcium ion binding|structural constituent of muscle|,8,-0.2,0.378,9,-0.6,2.26,-0.3,2.05,-2.05,0.499,0,0,-1.6,1.2
ENSMUSG00000026176,CTDSP1,"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1",nucleus|extracellular vesicular exosome|,negative regulation of protein phosphorylation|regulation of transcription from RNA polymerase II promoter|protein dephosphorylation|negative regulation of neuron differentiation|negative regulation of neurogenesis|negative regulation of neurogenesis|negative regulation of neurogenesis|negative regulation of G1/S transition of mitotic cell cycle|,phosphoprotein phosphatase activity|protein binding|CTD phosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|,10,-1,2.07,10,-0.2,1.45,-0.5,2.05,-2.05,0.499,0,0,-2,0.6
ENSMUSG00000026834,ACVR1C,"activin A receptor, type IC",cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|activin receptor complex|,trophectodermal cell proliferation|response to dietary excess|protein phosphorylation|apoptotic process|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor complex assembly|response to glucose|phosphorylation|lipid storage|cell differentiation|apoptotic nuclear changes|response to insulin|activin receptor signaling pathway|nodal signaling pathway|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of insulin secretion|negative regulation of trophoblast cell migration|negative regulation of chorionic trophoblast cell proliferation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|ATP binding|kinase activity|activin receptor activity, type I|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|nodal binding|SMAD binding|metal ion binding|activin binding|BMP receptor binding|",9,-0.2,0.458,9,-0.7,3.04,-0.2,2.05,-2.05,0.499,0,0,-2,0.7
ENSMUSG00000031995,ST14,suppression of tumorigenicity 14 (colon carcinoma),extracellular region|extracellular space|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|extrinsic component of plasma membrane|extrinsic component of plasma membrane|extracellular vesicular exosome|,proteolysis|proteolysis|cell migration|keratinocyte differentiation|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.7,1.64,10,-0.3,2.57,-0.3,2.03,-2.03,0.501,0,0,-1.1,1.7
ENSMUSG00000030739,MYH14,"myosin, heavy polypeptide 14",stress fiber|cytoplasm|membrane|myosin complex|myosin II complex|axon|growth cone|actomyosin|extracellular vesicular exosome|myosin II filament|,skeletal muscle contraction|ATP catabolic process|ATP catabolic process|skeletal muscle tissue development|sensory perception of sound|regulation of cell shape|skeletal muscle atrophy|neuronal action potential|actin filament-based movement|actomyosin structure organization|mitochondrion morphogenesis|vocalization behavior|,microfilament motor activity|nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|actin-dependent ATPase activity|actin-dependent ATPase activity|actin filament binding|actin filament binding|,9,0.4,0.889,9,0.7,1.49,0.5,2.03,2.03,0.501,0,0,-0.4,1.9
ENSMUSG00000028630,DYRK2,dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2,ubiquitin ligase complex|nucleus|cytoplasm|ribonucleoprotein complex|,protein phosphorylation|apoptotic process|smoothened signaling pathway|phosphorylation|peptidyl-tyrosine phosphorylation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of glycogen biosynthetic process|negative regulation of NFAT protein import into nucleus|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|manganese ion binding|ubiquitin binding|",7,-1.1,4.17,7,-0.2,0.194,-1.1,2.01,-2.01,0.503,0,0,-2,0.8
ENSMUSG00000019889,PTPRK,"protein tyrosine phosphatase, receptor type, K",photoreceptor outer segment|cell-cell junction|cell surface|membrane|integral component of membrane|axon|dendrite|leading edge membrane|neuronal cell body|,"protein dephosphorylation|protein dephosphorylation|cell adhesion|signal transduction|transforming growth factor beta receptor signaling pathway|negative regulation of cell proliferation|negative regulation of keratinocyte proliferation|dephosphorylation|cell migration|negative regulation of cell migration|neuron projection development|protein localization to cell surface|cellular response to reactive oxygen species|cellular response to UV|peptidyl-tyrosine dephosphorylation|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|focal adhesion assembly|",phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|beta-catenin binding|hydrolase activity|phosphatase activity|protein kinase binding|gamma-catenin binding|,10,0.6,1.16,10,0.3,1.26,0.3,2.01,2.01,0.503,0,0,-0.6,1.7
ENSMUSG00000027712,ANXA5,annexin A5,extracellular space|intracellular|nucleus|cytoplasm|plasma membrane|external side of plasma membrane|intercalated disc|membrane|Z disc|sarcolemma|cell projection|extracellular vesicular exosome|endothelial microparticle|,blood coagulation|hemostasis|response to organic substance|negative regulation of blood coagulation|positive regulation of apoptotic process|negative regulation of coagulation|protein homooligomerization|response to calcium ion|regulation of sperm motility|,calcium ion binding|protein binding|calcium-dependent phospholipid binding|peptide hormone binding|receptor tyrosine kinase binding|,10,-0.4,2.87,10,-0.1,0.123,-0.2,2.01,-2.01,0.503,0,0,-1.5,1.6
ENSMUSG00000021760,GPX8,glutathione peroxidase 8 (putative),cellular_component|membrane|integral component of membrane|,response to oxidative stress|oxidation-reduction process|,peroxidase activity|glutathione peroxidase activity|oxidoreductase activity|,9,0.3,2.34,9,-0.3,2.11,0.3,1.97,1.97,0.508,0,0,-1,1.5
ENSMUSG00000026818,CEL,carboxyl ester lipase,extracellular region|extracellular space|extracellular space|cytoplasm|rough endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|zymogen granule|intracellular membrane-bounded organelle|protein complex|membrane raft|extracellular vesicular exosome|,lipid metabolic process|cholesterol catabolic process|lipid catabolic process|pancreatic juice secretion|retinol metabolic process|ceramide catabolic process|,lysophospholipase activity|sterol esterase activity|triglyceride lipase activity|hydrolase activity|protein complex binding|glycosphingolipid binding|acylglycerol lipase activity|retinyl-palmitate esterase activity|carboxylic ester hydrolase activity|carboxylic ester hydrolase activity|,7,-0.8,3.91,7,0,0,-0.4,1.97,-1.97,0.508,0,0,-1.8,1.5
ENSMUSG00000068122,AGTR2,"angiotensin II receptor, type 2",intracellular|plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,"regulation of systemic arterial blood pressure by circulatory renin-angiotensin|renin-angiotensin regulation of aldosterone production|vasodilation by angiotensin involved in regulation of systemic arterial blood pressure|brain renin-angiotensin system|cellular sodium ion homeostasis|inflammatory response|inflammatory response|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|positive regulation of cell proliferation|negative regulation of heart rate|negative regulation of norepinephrine secretion|cerebellar cortex development|negative regulation of icosanoid secretion|positive regulation of phosphoprotein phosphatase activity|intracellular signal transduction|regulation of metanephros size|exploration behavior|positive regulation of renal sodium excretion|aldosterone secretion|angiotensin-activated signaling pathway|angiotensin-activated signaling pathway|regulation of vasodilation|dopamine biosynthetic process|regulation of apoptotic process|regulation of transcription factor import into nucleus|positive regulation of transcription, DNA-templated|positive regulation of vasodilation|negative regulation of fibroblast proliferation|positive regulation of cytokine secretion|positive regulation of nitric-oxide synthase activity|negative regulation of neurotrophin TRK receptor signaling pathway|kidney morphogenesis|cell growth involved in cardiac muscle cell development|cellular response to dexamethasone stimulus|positive regulation of metanephric glomerulus development|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of extrinsic apoptotic signaling pathway|",signal transducer activity|G-protein coupled receptor activity|angiotensin type II receptor activity|angiotensin type II receptor activity|angiotensin type II receptor activity|transcription factor binding|peptide hormone binding|,10,-0.4,2.57,10,-0.1,0.389,-0.3,1.97,-1.97,0.508,0,0,-1.5,0.6
ENSMUSG00000042688,MAPK6,mitogen-activated protein kinase 6,nucleus|cytoplasm|cytoplasm|,MAPK cascade|protein phosphorylation|cell cycle|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein heterodimerization activity|",10,0.3,1.7,10,0.2,0.493,0.2,1.96,1.96,0.509,0,0,-0.5,1.7
ENSMUSG00000070323,MMP27,matrix metallopeptidase 27,cellular_component|,proteolysis|biological_process|,molecular_function|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.8,2.12,10,-0.3,1.91,-0.3,1.94,-1.94,0.511,0,0,-0.9,1.9
ENSMUSG00000027073,PRG2,"proteoglycan 2, bone marrow",extracellular vesicular exosome|,defense response to nematode|immune system process|immune response|negative regulation of interleukin-10 production|positive regulation of interleukin-4 production|defense response to bacterium|,carbohydrate binding|,9,0.7,2.43,9,-0.5,0.289,0.3,1.92,1.92,0.513,0,0,-0.8,1.9
ENSMUSG00000029255,GNRHR,gonadotropin releasing hormone receptor,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of cell proliferation|,signal transducer activity|G-protein coupled receptor activity|gonadotropin-releasing hormone receptor activity|protein-hormone receptor activity|growth hormone-releasing hormone receptor activity|,8,-0.1,0.231,8,-0.7,3.5,-0.3,1.92,-1.92,0.513,0,0,-2,0.3
ENSMUSG00000061576,DPP6,dipeptidylpeptidase 6,voltage-gated potassium channel complex|cell surface|membrane|integral component of membrane|neuronal cell body|extracellular vesicular exosome|,proteolysis|neuronal action potential|regulation of membrane potential|regulation of potassium ion transport|positive regulation of potassium ion transport|regulation of potassium ion transmembrane transport|positive regulation of potassium ion transmembrane transport|,protein binding|serine-type peptidase activity|,10,0.1,0.474,10,-0.3,3.52,-0.2,1.92,-1.92,0.513,0,0,-1.4,0.9
ENSMUSG00000022329,STK3,serine/threonine kinase 3,intracellular|nucleus|cytoplasm|cytoplasm|,neural tube formation|endocardium development|protein phosphorylation|protein phosphorylation|apoptotic process|signal transduction|central nervous system development|negative regulation of cell proliferation|phosphorylation|signal transduction by phosphorylation|hippo signaling|hippo signaling|intracellular signal transduction|intracellular signal transduction|positive regulation of apoptotic process|positive regulation of JNK cascade|negative regulation of organ growth|positive regulation of protein kinase B signaling|primitive hemopoiesis|cell differentiation involved in embryonic placenta development|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|hepatocyte apoptotic process|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.2,1.25,10,-0.3,0.828,-0.3,1.92,-1.92,0.513,0,0,-1.3,1.2
ENSMUSG00000026034,CLK1,CDC-like kinase 1,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|peptidyl-tyrosine phosphorylation|regulation of RNA splicing|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-1,5.11,-1,1.88,-1.88,0.518,0,0,-2,0.3
ENSMUSG00000022416,CACNA1I,"calcium channel, voltage-dependent, alpha 1I subunit",intracellular|cell|plasma membrane|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|neuronal action potential|sleep|regulation of ion transmembrane transport|regulation of membrane potential|calcium ion transport into cytosol|calcium ion import|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|low voltage-gated calcium channel activity|,10,-0.3,0.295,10,-0.3,1.72,-0.3,1.88,-1.88,0.518,0,0,-1.5,1.2
ENSMUSG00000021587,PCSK1,proprotein convertase subtilisin/kexin type 1,extracellular space|extracellular space|Golgi apparatus|cytoplasmic vesicle|,proteolysis|protein processing|peptide hormone processing|peptide biosynthetic process|,endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.3,2.61,0.3,1.88,1.88,0.518,0,0,-0.6,1.6
ENSMUSG00000004056,AKT2,thymoma viral proto-oncogene 2,nucleus|cytoplasm|cytosol|plasma membrane|plasma membrane|cell cortex|membrane|vesicle|ruffle membrane|insulin-responsive compartment|intracellular membrane-bounded organelle|,positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|carbohydrate metabolic process|glycogen metabolic process|glycogen biosynthetic process|glucose metabolic process|regulation of translation|protein phosphorylation|protein phosphorylation|transport|apoptotic process|multicellular organismal development|insulin receptor signaling pathway|insulin receptor signaling pathway|carbohydrate transport|positive regulation of signal transduction|positive regulation of gene expression|negative regulation of plasma membrane long-chain fatty acid transport|positive regulation of sodium ion transport|positive regulation of glucose metabolic process|phosphorylation|positive regulation of cell migration|positive regulation of vesicle fusion|positive regulation of fatty acid beta-oxidation|peripheral nervous system myelin maintenance|activation of Ral GTPase activity|cellular response to insulin stimulus|cellular response to insulin stimulus|negative regulation of RNA splicing|positive regulation of peptidyl-serine phosphorylation|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|protein kinase B signaling|positive regulation of nitric oxide biosynthetic process|positive regulation of glycogen biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of glucose import|positive regulation of positive chemotaxis|intracellular protein transmembrane transport|cellular response to organic cyclic compound|protein localization to plasma membrane|positive regulation of protein targeting to membrane|positive regulation of cell motility|positive regulation of glucose import in response to insulin stimulus|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein kinase C binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.3,2.38,0.3,1.87,1.87,0.519,0,0,-1,1.4
ENSMUSG00000023972,PTK7,PTK7 protein tyrosine kinase 7,plasma membrane|cell-cell junction|cell-cell junction|membrane|integral component of membrane|cell junction|,establishment of planar polarity|neural tube closure|neural tube closure|axis elongation|cell adhesion|positive regulation of neuron projection development|Wnt signaling pathway|cell migration|actin cytoskeleton reorganization|wound healing|establishment of epithelial cell apical/basal polarity|convergent extension|canonical Wnt signaling pathway|lung-associated mesenchyme development|cellular response to retinoic acid|cochlea morphogenesis|planar cell polarity pathway involved in neural tube closure|,"protein kinase activity|protein tyrosine kinase activity|transferase activity, transferring phosphorus-containing groups|",10,0.3,2.49,10,-0.5,4.34,-0.5,1.86,-1.86,0.52,0,0,-1.3,1.5
ENSMUSG00000043154,PPP2R3A,"protein phosphatase 2, regulatory subunit B'', alpha",protein phosphatase type 2A complex|protein phosphatase type 2A complex|,eye photoreceptor cell differentiation|somatic muscle development|positive regulation of protein catabolic process|negative regulation of canonical Wnt signaling pathway|regulation of cell motility involved in somitogenic axis elongation|positive regulation of canonical Wnt signaling pathway|,molecular_function|,10,-0.4,3.76,10,0,0,-0.4,1.86,-1.86,0.52,0,0,-1.8,0.3
ENSMUSG00000033860,FGG,fibrinogen gamma chain,extracellular region|fibrinogen complex|extracellular space|cytoplasm|cell cortex|external side of plasma membrane|cell surface|platelet alpha granule|extracellular vesicular exosome|blood microparticle|,cell-matrix adhesion|signal transduction|blood coagulation|hemostasis|platelet activation|positive regulation of heterotypic cell-cell adhesion|cellular protein complex assembly|positive regulation of vasoconstriction|positive regulation of exocytosis|positive regulation of protein secretion|protein polymerization|response to calcium ion|positive regulation of ERK1 and ERK2 cascade|platelet aggregation|positive regulation of peptide hormone secretion|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of endothelial cell apoptotic process|,"receptor binding|structural molecule activity|protein binding, bridging|metal ion binding|cell adhesion molecule binding|",10,0.4,3.29,10,-0.3,1.23,0.4,1.85,1.85,0.521,0,0,-1.3,1.3
ENSMUSG00000063142,KCNMA1,"potassium large conductance calcium-activated channel, subfamily M, alpha member 1",cytoplasm|endoplasmic reticulum|plasma membrane|plasma membrane|caveola|voltage-gated potassium channel complex|voltage-gated potassium channel complex|external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|integral component of membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|virion|viral envelope|dendrite|neuronal cell body|terminal bouton|protein complex|postsynaptic membrane|perinuclear region of cytoplasm|presynaptic active zone membrane|extracellular vesicular exosome|,response to hypoxia|response to hypoxia|transport|ion transport|potassium ion transport|potassium ion transport|response to osmotic stress|synaptic transmission|sensory perception of sound|circadian rhythm|adult walking behavior|response to pH|neuronal action potential|cellular potassium ion homeostasis|response to corticosteroid|regulation of aldosterone metabolic process|response to carbon monoxide|regulation of ion transmembrane transport|vasodilation|regulation of vasodilation|regulation of membrane potential|regulation of membrane potential|regulation of membrane potential|auditory receptor cell differentiation|positive regulation of apoptotic process|response to estrogen|locomotor rhythm|negative regulation of cell volume|negative regulation of cell volume|saliva secretion|cell maturation|neuromuscular process controlling balance|protein homooligomerization|protein homotetramerization|response to calcium ion|transmembrane transport|micturition|micturition|eye blink reflex|smooth muscle contraction involved in micturition|smooth muscle contraction involved in micturition|relaxation of vascular smooth muscle|potassium ion transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,actin binding|ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|potassium channel activity|potassium channel activity|protein binding|calcium-activated potassium channel activity|calcium-activated potassium channel activity|calcium-activated potassium channel activity|calcium-activated potassium channel activity|protein complex binding|protein homodimerization activity|metal ion binding|large conductance calcium-activated potassium channel activity|large conductance calcium-activated potassium channel activity|large conductance calcium-activated potassium channel activity|,10,0.6,4.34,10,-0.1,0.028,0.3,1.82,1.82,0.525,0,0,-0.7,1.8
ENSMUSG00000032725,FOLR2,folate receptor 2 (fetal),intracellular|cell|plasma membrane|membrane|anchored component of membrane|anchored component of external side of plasma membrane|,posttranslational protein targeting to membrane|transport|folic acid transport|folic acid transport|,folic acid binding|folic acid binding|folic acid transporter activity|folic acid transporter activity|,10,-0.4,2.87,10,-0.1,0.377,-0.3,1.8,-1.8,0.527,0,0,-1.8,0.4
ENSMUSG00000031381,PIGA,"phosphatidylinositol glycan anchor biosynthesis, class A",glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|biosynthetic process|,"transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.717,10,0.2,1.21,0.2,1.79,1.79,0.528,0,0,-0.7,1.6
ENSMUSG00000046223,PLAUR,"plasminogen activator, urokinase receptor",extracellular region|plasma membrane|integral component of plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,positive regulation of gene expression|phosphorylation|urokinase plasminogen activator signaling pathway|negative regulation of apoptotic process|mesenchymal cell differentiation|epithelial cell differentiation involved in prostate gland development|,protein binding|kinase activity|transferase activity|enzyme binding|urokinase plasminogen activator receptor activity|,10,-0.6,1.68,10,-0.2,0.958,-0.2,1.77,-1.77,0.531,0,0,-1.8,0.8
ENSMUSG00000032067,PTS,6-pyruvoyl-tetrahydropterin synthase,cytoplasm|mitochondrion|mitochondrion|,tetrahydrobiopterin biosynthetic process|,6-pyruvoyltetrahydropterin synthase activity|6-pyruvoyltetrahydropterin synthase activity|protein binding|lyase activity|identical protein binding|identical protein binding|protein homodimerization activity|metal ion binding|,10,0.3,2.69,10,0,0,0.3,1.77,1.77,0.531,0,0,-0.6,1.6
ENSMUSG00000061130,PPM1B,"protein phosphatase 1B, magnesium dependent, beta isoform",cytoplasm|cytosol|membrane|,protein dephosphorylation|protein dephosphorylation|N-terminal protein myristoylation|negative regulation of interferon-beta production|peptidyl-threonine dephosphorylation|negative regulation of NF-kappaB import into nucleus|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of defense response to virus|,magnesium ion binding|catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|hydrolase activity|manganese ion binding|metal ion binding|,10,-0.3,1.48,10,-0.3,0.425,-0.3,1.77,-1.77,0.531,0,0,-1.5,1
ENSMUSG00000043089,MMP1A,matrix metallopeptidase 1a (interstitial collagenase),extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|extracellular matrix|,proteolysis|positive regulation of fibroblast migration|positive regulation of smooth muscle cell migration|collagen catabolic process|,metalloendopeptidase activity|calcium ion binding|peptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.4,2.08,10,-0.6,0.582,-0.6,1.76,-1.76,0.532,0,0,-1.7,1
ENSMUSG00000025069,GSTO2,glutathione S-transferase omega 2,cytoplasm|extracellular vesicular exosome|,xenobiotic metabolic process|metabolic process|L-ascorbic acid metabolic process|oxidation-reduction process|cellular response to arsenic-containing substance|,glutathione transferase activity|oxidoreductase activity|transferase activity|glutathione dehydrogenase (ascorbate) activity|methylarsonate reductase activity|,10,0.3,1.5,10,0.1,0.649,0.2,1.71,1.71,0.538,0,0,-1.6,1.2
ENSMUSG00000043029,TRPV3,"transient receptor potential cation channel, subfamily V, member 3",membrane|integral component of membrane|receptor complex|,transport|ion transport|cation transport|calcium ion transport|response to temperature stimulus|ion transmembrane transport|negative regulation of hair cycle|transmembrane transport|calcium ion transmembrane transport|positive regulation of calcium ion import|,ion channel activity|cation channel activity|calcium channel activity|protein binding|,10,-0.5,3.4,10,-0.1,0.0968,-0.4,1.7,-1.7,0.539,0,0,-1.6,1.1
ENSMUSG00000074377,SULT2A4,"sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4",cellular_component|cytoplasm|cytosol|,biological_process|,alcohol sulfotransferase activity|drug binding|sulfotransferase activity|transferase activity|3'-phosphoadenosine 5'-phosphosulfate binding|,10,0,0,10,-0.2,2.41,-0.2,1.68,-1.68,0.541,0,0,-1.5,0.9
ENSMUSG00000000530,ACVRL1,"activin A receptor, type II-like 1",integral component of plasma membrane|cell surface|membrane|integral component of membrane|dendrite|neuronal cell body|,"angiogenesis|angiogenesis|in utero embryonic development|negative regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|lymphangiogenesis|blood vessel remodeling|regulation of transcription, DNA-templated|protein phosphorylation|negative regulation of cell adhesion|signal transduction|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|blood circulation|regulation of blood pressure|negative regulation of cell proliferation|negative regulation of endothelial cell migration|positive regulation of pathway-restricted SMAD protein phosphorylation|phosphorylation|signal transduction by phosphorylation|negative regulation of cell growth|negative regulation of cell migration|BMP signaling pathway|BMP signaling pathway|positive regulation of BMP signaling pathway|positive regulation of BMP signaling pathway|activin receptor signaling pathway|wound healing, spreading of epidermal cells|intracellular signal transduction|endothelial cell activation|negative regulation of blood vessel endothelial cell migration|negative regulation of endothelial cell differentiation|positive regulation of endothelial cell differentiation|positive regulation of angiogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|blood vessel morphogenesis|protein heterooligomerization|negative regulation of focal adhesion assembly|lymphatic endothelial cell differentiation|lymphatic endothelial cell differentiation|artery development|venous blood vessel development|endothelial tube morphogenesis|retina vasculature development in camera-type eye|cellular response to transforming growth factor beta stimulus|cellular response to transforming growth factor beta stimulus|cellular response to BMP stimulus|negative regulation of DNA biosynthetic process|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta receptor activity, type I|transforming growth factor beta receptor activity, type I|protein binding|ATP binding|kinase activity|activin receptor activity, type I|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|SMAD binding|metal ion binding|activin binding|transforming growth factor beta binding|",10,-0.2,0.234,10,-0.4,1.76,-0.3,1.68,-1.68,0.541,0,0,-1.6,1.1
ENSMUSG00000022617,CHKB,choline kinase beta,None,lipid metabolic process|phosphatidylethanolamine biosynthetic process|phosphatidylcholine biosynthetic process|CDP-choline pathway|CDP-choline pathway|muscle organ development|phospholipid biosynthetic process|phosphorylation|,"nucleotide binding|choline kinase activity|choline kinase activity|ethanolamine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.468,10,-0.7,2.71,-0.2,1.67,-1.67,0.542,0,0,-2,1
ENSMUSG00000038855,ITPKB,"inositol 1,4,5-trisphosphate 3-kinase B",intracellular|,MAPK cascade|cell surface receptor signaling pathway|phosphorylation|T cell differentiation|positive thymic T cell selection|thymic T cell selection|positive regulation of Ras protein signal transduction|positive regulation of alpha-beta T cell differentiation|,"nucleotide binding|ATP binding|inositol-1,4,5-trisphosphate 3-kinase activity|inositol-1,4,5-trisphosphate 3-kinase activity|kinase activity|transferase activity|",10,0.2,0.91,9,-1,4.47,-1,1.66,-1.66,0.544,0,0,-2,0.8
ENSMUSG00000003099,PPP5C,"protein phosphatase 5, catalytic subunit",nucleus|cytoplasm|cytosol|membrane|neuron projection|neuronal cell body|intracellular membrane-bounded organelle|,protein dephosphorylation|signal transduction|dephosphorylation|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to morphine|protein heterooligomerization|,RNA binding|phosphoprotein phosphatase activity|phosphoprotein phosphatase activity|signal transducer activity|protein binding|hydrolase activity|identical protein binding|metal ion binding|,9,0.5,3.01,9,-0.4,1.22,0.2,1.66,1.66,0.544,0,0,-1.1,1.6
ENSMUSG00000026385,DBI,diazepam binding inhibitor,extracellular space|nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|plasma membrane|synaptic vesicle|contractile fiber|extracellular vesicular exosome|perinuclear endoplasmic reticulum|,"hair follicle development|triglyceride metabolic process|transport|glial cell proliferation|negative regulation of fatty acid beta-oxidation|regulation of synaptic transmission, GABAergic|phosphatidylcholine acyl-chain remodeling|skin development|positive regulation of lipid biosynthetic process|positive regulation of release of sequestered calcium ion into cytosol|",fatty-acyl-CoA binding|lipid binding|benzodiazepine receptor binding|long-chain fatty acyl-CoA binding|protein dimerization activity|,10,1,2.07,10,0.2,1.1,0.4,1.66,1.66,0.544,0,0,-1.1,2
ENSMUSG00000052155,ACVR2A,activin receptor IIA,cytoplasm|cell surface|membrane|integral component of membrane|inhibin-betaglycan-ActRII complex|,gastrulation with mouth forming second|positive regulation of protein phosphorylation|protein phosphorylation|transmembrane receptor protein serine/threonine kinase signaling pathway|spermatogenesis|determination of left/right symmetry|mesoderm development|male gonad development|anterior/posterior pattern specification|regulation of signal transduction|positive regulation of pathway-restricted SMAD protein phosphorylation|phosphorylation|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|regulation of BMP signaling pathway|activin receptor signaling pathway|positive regulation of activin receptor signaling pathway|sperm ejaculation|penile erection|positive regulation of erythrocyte differentiation|positive regulation of osteoblast differentiation|positive regulation of follicle-stimulating hormone secretion|embryonic skeletal system development|regulation of nitric-oxide synthase activity|Sertoli cell proliferation|cellular response to BMP stimulus|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|protein binding|ATP binding|coreceptor activity|kinase activity|activin receptor activity, type II|transferase activity|transferase activity, transferring phosphorus-containing groups|activin-activated receptor activity|growth factor binding|growth factor binding|PDZ domain binding|inhibin binding|inhibin binding|protein self-association|metal ion binding|activin binding|activin binding|activin binding|",10,0.5,1.34,10,-0.3,0.808,-0.3,1.66,-1.66,0.544,0,0,-1.3,1.3
ENSMUSG00000025375,AATK,apoptosis-associated tyrosine kinase,intracellular|cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|cell projection|axonal growth cone|perinuclear region of cytoplasm|recycling endosome|,protein phosphorylation|apoptotic process|brain development|phosphorylation|negative regulation of axon extension|negative regulation of axon extension|Rab protein signal transduction|peptidyl-tyrosine autophosphorylation|peptidyl-tyrosine autophosphorylation|protein autophosphorylation|neuron apoptotic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.43,10,-0.8,3.11,-0.2,1.64,-1.64,0.546,0,0,-2,0.5
ENSMUSG00000040687,MADD,MAP-kinase activating death domain,cytoplasm|plasma membrane|membrane|integral component of membrane|,activation of MAPK activity|activation of MAPK activity|apoptotic process|regulation of Rab protein signal transduction|positive regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|regulation of apoptotic process|regulation of cell cycle|regulation of cell cycle|execution phase of apoptosis|execution phase of apoptosis|regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of apoptotic signaling pathway|regulation of extrinsic apoptotic signaling pathway|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.9,3.57,10,-0.1,0.42,-0.3,1.63,-1.63,0.547,0,0,-1.9,0.2
ENSMUSG00000020436,GABRG2,"gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2",cytoplasm|plasma membrane|membrane|integral component of membrane|cell junction|axon|dendrite membrane|chloride channel complex|synapse|postsynaptic membrane|inhibitory synapse|,"transport|ion transport|chloride transport|signal transduction|gamma-aminobutyric acid signaling pathway|synaptic transmission|post-embryonic development|adult behavior|synaptic transmission, GABAergic|chloride transmembrane transport|",GABA-A receptor activity|GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|protein binding|,10,0.2,0.681,10,-0.4,3.27,-0.3,1.61,-1.61,0.55,0,0,-1.7,0.8
ENSMUSG00000059883,IRAK4,interleukin-1 receptor-associated kinase 4,extracellular space|intracellular|cytoplasm|,cytokine production|immune system process|protein phosphorylation|signal transduction|JNK cascade|phosphorylation|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|positive regulation of smooth muscle cell proliferation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|interleukin-1 receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.767,10,0.3,1.08,0.3,1.61,1.61,0.55,0,0,-0.4,1.8
ENSMUSG00000020621,RDH14,retinol dehydrogenase 14 (all-trans and 9-cis),nucleus|mitochondrion|lysosomal membrane|endoplasmic reticulum|membrane|,osteoblast differentiation|metabolic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|molecular_function|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0,0,10,-0.3,2.27,-0.2,1.61,-1.61,0.55,0,0,-1.5,0.9
ENSMUSG00000027820,MME,membrane metallo endopeptidase,cytoplasm|plasma membrane|brush border|synaptic vesicle|membrane|membrane|integral component of membrane|axon|dendrite|neuron projection terminus|synapse|extracellular vesicular exosome|,proteolysis|proteolysis|peptide metabolic process|sensory perception of pain|creatinine metabolic process|beta-amyloid metabolic process|cellular response to cytokine stimulus|cellular response to UV-A|cellular response to UV-B|,endopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|peptide binding|metal ion binding|,10,0.5,4.25,10,0,0,0.5,1.61,1.61,0.55,0,0,-0.8,1.6
ENSMUSG00000073409,H2-Q6,"histocompatibility 2, Q region locus 6",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|cell surface|membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,None,receptor binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,9,0,0,9,-0.4,2.57,-0.3,1.59,-1.59,0.552,0,0,-1.8,0.5
ENSMUSG00000050511,OPRD1,"opioid receptor, delta 1",cytoplasm|plasma membrane|membrane|integral component of membrane|intrinsic component of plasma membrane|vesicle|dendrite membrane|axon terminus|membrane raft|postsynaptic membrane|,"protein import into nucleus, translocation|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|adult locomotory behavior|opioid receptor signaling pathway|opioid receptor signaling pathway|regulation of calcium ion transport|regulation of sensory perception of pain|",signal transducer activity|G-protein coupled receptor activity|opioid receptor activity|opioid receptor activity|opioid receptor activity|enkephalin receptor activity|,10,1.2,4.59,10,0.1,0.292,0.1,1.58,1.58,0.554,0,0,-0.6,2
ENSMUSG00000032561,ACPP,"acid phosphatase, prostate",extracellular region|extracellular space|intracellular|nucleus|lysosome|lysosomal membrane|multivesicular body|plasma membrane|plasma membrane|vesicle membrane|membrane|integral component of membrane|secretory granule|filopodium|Golgi cisterna|apical part of cell|extracellular vesicular exosome|,purine nucleobase metabolic process|thiamine metabolic process|nucleotide metabolic process|dephosphorylation|dephosphorylation|adenosine metabolic process|adenosine metabolic process|regulation of sensory perception of pain|regulation of sensory perception of pain|positive regulation of adenosine receptor signaling pathway|,acid phosphatase activity|acid phosphatase activity|5'-nucleotidase activity|hydrolase activity|phosphatase activity|choline binding|thiamine phosphate phosphatase activity|identical protein binding|protein homodimerization activity|lysophosphatidic acid phosphatase activity|,9,-0.2,0.941,9,-0.2,0.774,-0.2,1.58,-1.58,0.554,0,0,-1.6,1.1
ENSMUSG00000028597,GPX7,glutathione peroxidase 7,extracellular region|endoplasmic reticulum|,response to oxidative stress|oxidation-reduction process|,peroxidase activity|glutathione peroxidase activity|oxidoreductase activity|,10,-0.2,0.712,10,-0.2,0.998,-0.2,1.58,-1.58,0.554,0,0,-1.6,0.9
ENSMUSG00000017781,PITPNA,"phosphatidylinositol transfer protein, alpha",intracellular|cytoplasm|integral component of membrane|extracellular vesicular exosome|,transport|phospholipid transport|,fatty-acyl-CoA binding|phospholipid binding|lipid binding|phosphatidylinositol transporter activity|phosphatidylinositol binding|stearic acid binding|,10,-0.3,2.6,10,0.3,1.75,-0.3,1.56,-1.56,0.557,0,0,-1.3,1.1
ENSMUSG00000028712,CYP4A31,"cytochrome P450, family 4, subfamily a, polypeptide 31",cytoplasm|apical plasma membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,leukotriene B4 catabolic process|oxidation-reduction process|,monooxygenase activity|arachidonic acid monooxygenase activity|arachidonic acid epoxygenase activity|oxidoreductase activity|alkane 1-monooxygenase activity|metal ion binding|leukotriene-B4 20-monooxygenase activity|,9,-0.2,0.858,9,0.4,3.03,0.3,1.56,1.56,0.557,0,0,-0.7,1.8
ENSMUSG00000000339,RTCA,RNA 3'-terminal phosphate cyclase,nucleus|,RNA processing|,nucleotide binding|catalytic activity|RNA-3'-phosphate cyclase activity|ATP binding|ligase activity|poly(A) RNA binding|,10,1,2.44,10,-0.3,1.03,-0.2,1.56,-1.56,0.557,0,0,-1,2
ENSMUSG00000021684,PDE8B,phosphodiesterase 8B,cellular_component|,phosphorelay signal transduction system|behavioral fear response|signal transduction|visual learning|operant conditioning|negative regulation of insulin secretion|neuromuscular process controlling balance|negative regulation of steroid hormone biosynthetic process|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|signal transducer activity|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|",10,1.4,4.68,10,-0.1,0.075,1.3,1.54,1.54,0.559,0,0,-0.6,2
ENSMUSG00000020580,ROCK2,Rho-associated coiled-coil containing protein kinase 2,nucleus|cytoplasm|centrosome|centrosome|cytoskeleton|plasma membrane|membrane|spindle pole centrosome|cytoplasmic ribonucleoprotein granule|,neural tube closure|protein phosphorylation|Rho protein signal transduction|extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of centrosome duplication|phosphorylation|negative regulation of angiogenesis|actin cytoskeleton organization|intracellular signal transduction|regulation of circadian rhythm|regulation of keratinocyte differentiation|rhythmic process|centrosome duplication|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rho GTPase binding|poly(A) RNA binding|metal ion binding|",10,-0.2,0.66,9,-0.6,1.24,-0.2,1.53,-1.53,0.56,0,0,-1.8,0.6
ENSMUSG00000052488,CHERP,calcium homeostasis endoplasmic reticulum protein,cytoplasm|endoplasmic reticulum|membrane|sarcoplasmic reticulum membrane|perinuclear region of cytoplasm|,RNA processing|cellular calcium ion homeostasis|negative regulation of cell proliferation|release of sequestered calcium ion into cytosol|positive regulation of NFAT protein import into nucleus|,nucleic acid binding|RNA binding|ion channel binding|poly(A) RNA binding|,7,-0.4,1.65,8,0.3,0.687,-0.2,1.53,-1.53,0.56,0,0,-1.6,1.3
ENSMUSG00000031344,GABRQ,"gamma-aminobutyric acid (GABA) A receptor, subunit theta",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|receptor complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|gamma-aminobutyric acid signaling pathway|,GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|,10,0.1,0.47,10,0.5,1.6,0.4,1.53,1.53,0.56,0,0,-1.3,1.4
ENSMUSG00000018585,ATOX1,ATX1 (antioxidant protein 1) homolog 1 (yeast),intracellular|,transport|ion transport|copper ion transport|cellular copper ion homeostasis|cellular copper ion homeostasis|response to oxidative stress|intracellular copper ion transport|metal ion transport|copper ion transmembrane transport|,copper ion transmembrane transporter activity|copper ion binding|copper chaperone activity|copper-dependent protein binding|metal ion binding|,10,0.3,1.73,10,-0.1,0.191,0.2,1.51,1.51,0.563,0,0,-0.9,1.5
ENSMUSG00000053046,BRSK2,BR serine/threonine kinase 2,cytoplasm|endoplasmic reticulum|centrosome|cytoskeleton|,G2/M transition of mitotic cell cycle|protein phosphorylation|protein phosphorylation|protein phosphorylation|exocytosis|apoptotic process|cell cycle|mitotic nuclear division|nervous system development|axonogenesis|phosphorylation|peptidyl-serine phosphorylation|establishment of cell polarity|establishment of cell polarity|neuron differentiation|actin cytoskeleton reorganization|neuron projection morphogenesis|cell division|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of insulin secretion involved in cellular response to glucose stimulus|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|metal ion binding|tau-protein kinase activity|tau-protein kinase activity|tau-protein kinase activity|",9,0.5,2.1,9,0,0,0.2,1.51,1.51,0.563,0,0,-0.5,1.9
ENSMUSG00000001127,ARAF,v-raf murine sarcoma 3611 viral oncogene homolog,mitochondrion|cytosol|,MAPK cascade|activation of MAPKK activity|protein phosphorylation|signal transduction|phosphorylation|regulation of TOR signaling|regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of peptidyl-serine phosphorylation|intracellular signal transduction|negative regulation of apoptotic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|receptor signaling protein activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.2,0.205,10,0.4,1.77,0.7,1.5,1.5,0.564,0,0,-0.5,1.9
ENSMUSG00000028093,ACP6,"acid phosphatase 6, lysophosphatidic",cytoplasm|mitochondrion|mitochondrion|,hematopoietic progenitor cell differentiation|lipid metabolic process|phospholipid metabolic process|dephosphorylation|lysobisphosphatidic acid metabolic process|,acid phosphatase activity|hydrolase activity|lysophosphatidic acid phosphatase activity|,10,0,0,10,0.5,2.03,0.5,1.5,1.5,0.564,0,0,-0.9,1.8
ENSMUSG00000089917,UCKL1,uridine-cytidine kinase 1-like 1,nucleus|cytoplasm|,biological_process|metabolic process|phosphorylation|,"nucleotide binding|uridine kinase activity|ATP binding|phosphofructokinase activity|phosphorylase kinase regulator activity|cobinamide kinase activity|phytol kinase activity|kinase activity|phosphatidylinositol phosphate kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|phenol kinase activity|cyclin-dependent protein kinase activating kinase regulator activity|inositol tetrakisphosphate 2-kinase activity|heptose 7-phosphate kinase activity|aminoglycoside phosphotransferase activity|phosphatidylinositol 3-kinase activity|eukaryotic elongation factor-2 kinase regulator activity|eukaryotic elongation factor-2 kinase activator activity|LPPG:FO 2-phospho-L-lactate transferase activity|cytidine kinase activity|glycerate 2-kinase activity|(S)-lactate 2-kinase activity|phosphoserine:homoserine phosphotransferase activity|L-seryl-tRNA(Sec) kinase activity|phosphocholine transferase activity|polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide kinase activity|GTP-dependent polynucleotide kinase activity|farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|geraniol kinase activity|geranylgeraniol kinase activity|CTP:geranylgeraniol kinase activity|prenol kinase activity|1-phosphatidylinositol-5-kinase activity|1-phosphatidylinositol-3-phosphate 4-kinase activity|phosphatidylinositol-3,4-bisphosphate 5-kinase activity|phosphatidylinositol bisphosphate kinase activity|inositol-3,4,6-trisphosphate 1-kinase activity|inositol 5-diphosphate pentakisphosphate 5-kinase activity|inositol diphosphate tetrakisphosphate kinase activity|",10,-0.3,2.15,10,0.4,1.64,-0.3,1.5,-1.5,0.564,0,0,-1.3,1.3
ENSMUSG00000001901,KCNH6,"potassium voltage-gated channel, subfamily H (eag-related), member 6",integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|regulation of membrane potential|protein heterooligomerization|potassium ion transmembrane transport|potassium ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|,10,-0.5,1.53,10,-0.6,0.165,-0.6,1.49,-1.49,0.566,0,0,-1.8,0.5
ENSMUSG00000022186,OXCT1,3-oxoacid CoA transferase 1,mitochondrion|mitochondrion|,metabolic process|positive regulation of insulin secretion involved in cellular response to glucose stimulus|ketone catabolic process|cellular ketone body metabolic process|cellular ketone body metabolic process|ketone body catabolic process|,3-oxoacid CoA-transferase activity|3-oxoacid CoA-transferase activity|CoA-transferase activity|transferase activity|protein homodimerization activity|,9,0.4,1.41,9,0.3,0.367,0.4,1.49,1.49,0.566,0,0,-0.6,1.8
ENSMUSG00000056666,RETSAT,"retinol saturase (all trans retinol 13,14 reductase)",nuclear outer membrane|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|nuclear membrane|,retinol metabolic process|oxidation-reduction process|,"oxidoreductase activity|all-trans-retinol 13,14-reductase activity|",10,-0.4,3.43,10,0.1,0.00585,-0.4,1.48,-1.48,0.567,0,0,-1.9,0.5
ENSMUSG00000028028,ALPK1,alpha-kinase 1,cellular_component|,protein phosphorylation|biological_process|phosphorylation|,"molecular_function|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|ATP binding|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,-0.1,0.256,10,-0.3,1.54,-0.2,1.47,-1.47,0.569,0,0,-1.8,0.6
ENSMUSG00000039384,DUSP10,dual specificity phosphatase 10,nucleus|cytoplasm|Golgi apparatus|,inactivation of MAPK activity|regulation of adaptive immune response|protein dephosphorylation|protein dephosphorylation|dephosphorylation|response to lipopolysaccharide|negative regulation of stress-activated MAPK cascade|negative regulation of JUN kinase activity|regulation of innate immune response|negative regulation of JNK cascade|oligodendrocyte differentiation|negative regulation of oligodendrocyte differentiation|negative regulation of respiratory burst involved in inflammatory response|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|MAP kinase phosphatase activity|,10,-0.5,2.83,10,0.1,0.0608,-0.3,1.43,-1.43,0.574,0,0,-1.9,0.5
ENSMUSG00000038615,NFE2L1,"nuclear factor, erythroid derived 2,-like 1",nucleus|cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|,"regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|erythrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,1,4.3,10,0.1,0.737,1,1.42,1.42,0.576,0,0,-0.1,2
ENSMUSG00000045569,MC2R,melanocortin 2 receptor,cytoplasm|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cAMP biosynthetic process|,signal transducer activity|G-protein coupled receptor activity|melanocortin receptor activity|corticotropin receptor activity|,10,0.5,3.77,10,0,0,0.4,1.41,1.41,0.577,0,0,-0.4,1.8
ENSMUSG00000050708,FTL1,ferritin light chain 1,cytoplasm|intracellular ferritin complex|membrane|extracellular vesicular exosome|,None,iron ion binding|identical protein binding|,7,0.7,2.52,7,0.2,0.374,0.3,1.41,1.41,0.577,0,0,-0.7,2
ENSMUSG00000027673,NDUFB5,"NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|membrane|integral component of membrane|respiratory chain|,transport|biological_process|oxidation-reduction process|,molecular_function|,10,-0.4,2.7,9,-1.1,2.57,-1.1,1.4,-1.4,0.578,0,0,-2,0.7
ENSMUSG00000024673,MS4A1,"membrane-spanning 4-domains, subfamily A, member 1",extracellular space|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,B cell activation|,epidermal growth factor receptor binding|MHC class II protein complex binding|,10,-0.2,1.72,10,-0.1,0.00787,-0.2,1.36,-1.36,0.584,0,0,-1.7,0.7
ENSMUSG00000032093,CD3E,"CD3 antigen, epsilon polypeptide",immunological synapse|plasma membrane|cell-cell junction|external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|T cell receptor complex|alpha-beta T cell receptor complex|,positive regulation of T cell anergy|cell surface receptor signaling pathway|response to nutrient|T cell costimulation|positive regulation of interferon-gamma production|positive regulation of interleukin-4 production|positive regulation of T cell proliferation|positive regulation of T cell proliferation|negative thymic T cell selection|positive regulation of interleukin-2 biosynthetic process|negative regulation of smoothened signaling pathway|positive regulation of alpha-beta T cell proliferation|lymphocyte activation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of calcium-mediated signaling|T cell receptor signaling pathway|positive regulation of T cell activation|apoptotic signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|protein binding|SH3 domain binding|protein heterodimerization activity|,10,-0.5,2.99,10,0.2,0.645,-0.4,1.36,-1.36,0.584,0,0,-1.5,0.9
ENSMUSG00000021559,DAPK1,death associated protein kinase 1,cytoplasm|actin cytoskeleton|,regulation of translation|protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|signal transduction|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|phosphorylation|negative regulation of translation|intracellular signal transduction|intracellular signal transduction|negative regulation of apoptotic process|protein autophosphorylation|cellular response to interferon-gamma|cellular response to interferon-gamma|apoptotic signaling pathway|apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|regulation of N-methyl-D-aspartate selective glutamate receptor activity|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin-dependent protein kinase activity|protein binding|calmodulin binding|calmodulin binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|",10,-0.4,3.55,10,0.2,0.626,-0.3,1.34,-1.34,0.587,0,0,-1.8,0.8
ENSMUSG00000050553,GK2,glycerol kinase 2,cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|extracellular vesicular exosome|,carbohydrate metabolic process|glycerol metabolic process|glycerol-3-phosphate metabolic process|phosphorylation|,"nucleotide binding|glycerol kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|",10,-0.1,0.612,10,-0.6,1.25,-0.2,1.33,-1.33,0.588,0,0,-1.8,0.8
ENSMUSG00000028044,CKS1B,CDC28 protein kinase 1b,None,cell cycle|cell division|,cyclin-dependent protein serine/threonine kinase regulator activity|,10,0.1,0.398,10,0.2,1.17,0.2,1.32,1.32,0.59,0,0,-1.2,1.5
ENSMUSG00000030347,D6WSU163E,"DNA segment, Chr 6, Wayne State University 163, expressed",cellular_component|,biological_process|,molecular_function|,10,0.3,1.53,10,-0.2,0.703,-0.2,1.32,-1.32,0.59,0,0,-1.1,1.3
ENSMUSG00000032577,MAPKAPK3,mitogen-activated protein kinase-activated protein kinase 3,nucleus|cytoplasm|nuclear membrane|,toll-like receptor signaling pathway|protein phosphorylation|phosphorylation|peptidyl-serine phosphorylation|response to lipopolysaccharide|response to cytokine|macropinocytosis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.3,3,10,0.1,0.378,-0.3,1.31,-1.31,0.591,0,0,-1.5,0.9
ENSMUSG00000022016,AKAP11,A kinase (PRKA) anchor protein 11,cytoplasm|peroxisome|protein complex|,regulation of protein kinase A signaling|regulation of phosphorylation|regulation of catalytic activity|,kinase regulator activity|protein complex scaffold|protein kinase A catalytic subunit binding|protein kinase A regulatory subunit binding|,10,-0.2,1.25,10,-0.1,0.383,-0.2,1.31,-1.31,0.591,0,0,-1.8,0.7
ENSMUSG00000069805,FBP1,fructose bisphosphatase 1,cytoplasm|cytosol|extracellular vesicular exosome|,carbohydrate metabolic process|fructose 6-phosphate metabolic process|gluconeogenesis|regulation of gluconeogenesis|metabolic process|dephosphorylation|negative regulation of cell growth|cellular response to drug|negative regulation of glycolytic process|negative regulation of Ras protein signal transduction|protein homotetramerization|cellular response to magnesium ion|,"catalytic activity|AMP binding|hydrolase activity|fructose 1,6-bisphosphate 1-phosphatase activity|phosphoric ester hydrolase activity|identical protein binding|metal ion binding|monosaccharide binding|",10,-0.2,1.36,10,0.3,1.45,0.2,1.29,1.29,0.594,0,0,-1.2,1.4
ENSMUSG00000020253,PPM1M,protein phosphatase 1M,nucleus|,protein dephosphorylation|,catalytic activity|phosphoprotein phosphatase activity|CTD phosphatase activity|hydrolase activity|manganese ion binding|metal ion binding|,10,0.1,0.514,10,0.3,1.14,0.2,1.26,1.26,0.598,0,0,-0.6,1.8
ENSMUSG00000090165,UGT1A10,"UDP glycosyltransferase 1 family, polypeptide A10",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,negative regulation of catalytic activity|,"enzyme inhibitor activity|protein kinase C binding|steroid binding|fatty acid binding|drug binding|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|enzyme binding|protein homodimerization activity|protein heterodimerization activity|",4,-0.2,0.404,4,-0.5,1.47,-0.3,1.25,-1.25,0.6,0,0,-2,1.2
ENSMUSG00000057672,PKN1,protein kinase N1,nucleus|cytoplasm|cytoplasm|endosome|plasma membrane|membrane|cytoplasmic membrane-bounded vesicle|midbody|cleavage furrow|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|protein phosphorylation|protein phosphorylation|hyperosmotic response|signal transduction|epithelial cell migration|phosphorylation|chromatin modification|histone H3-T11 phosphorylation|regulation of cell motility|","nucleotide binding|chromatin binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein kinase C binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|GTP-Rho binding|ligand-dependent nuclear receptor transcription coactivator activity|histone kinase activity (H3-T11 specific)|histone binding|histone deacetylase binding|Rac GTPase binding|androgen receptor binding|",10,0.2,0.91,10,0.2,0.449,0.2,1.25,1.25,0.6,0,0,-1.3,1.4
ENSMUSG00000007038,NEU1,neuraminidase 1,lysosome|lysosome|plasma membrane|cell surface|membrane|cell junction|cytoplasmic vesicle|intracellular membrane-bounded organelle|extracellular vesicular exosome|,carbohydrate metabolic process|lipid metabolic process|metabolic process|oligosaccharide catabolic process|positive regulation of neuron projection development|lipid catabolic process|regulation of myoblast proliferation|,"exo-alpha-sialidase activity|exo-alpha-sialidase activity|protein binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|exo-alpha-(2->3)-sialidase activity|exo-alpha-(2->6)-sialidase activity|exo-alpha-(2->8)-sialidase activity|",10,0.3,1.5,10,0.1,0.139,0.2,1.24,1.24,0.601,0,0,-0.9,1.6
ENSMUSG00000023191,LEPREL2,leprecan-like 2,cellular_component|endoplasmic reticulum|,negative regulation of cell proliferation|oxidation-reduction process|,"molecular_function|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|procollagen-proline 3-dioxygenase activity|L-ascorbic acid binding|metal ion binding|dioxygenase activity|",10,-0.8,3.51,9,0.2,0.811,-0.7,1.23,-1.23,0.603,0,0,-1.9,0.8
ENSMUSG00000024099,NDUFV2,NADH dehydrogenase (ubiquinone) flavoprotein 2,mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex I|mitochondrial respiratory chain complex I|membrane|respiratory chain|,"mitochondrial electron transport, NADH to ubiquinone|mitochondrial electron transport, NADH to ubiquinone|transport|nervous system development|cardiac muscle tissue development|oxidation-reduction process|","NADH dehydrogenase activity|NADH dehydrogenase (ubiquinone) activity|NADH dehydrogenase (ubiquinone) activity|electron carrier activity|oxidoreductase activity|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",7,0.2,1.07,9,0.1,0.375,0.2,1.22,1.22,0.605,0,0,-1.1,1.7
ENSMUSG00000051590,MAP3K19,mitogen-activated protein kinase kinase kinase 19,None,MAPK cascade|activation of MAPKK activity|protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.3,1.73,10,0,0,0.3,1.22,1.22,0.605,0,0,-1.1,1.6
ENSMUSG00000026235,EPHA4,Eph receptor A4,cytoplasm|mitochondrial outer membrane|endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cell surface|postsynaptic density|membrane|integral component of membrane|cell junction|filopodium|axon|dendrite|dendrite|neuromuscular junction|early endosome membrane|cell projection|dendritic spine|perikaryon|axon terminus|axonal growth cone|cell body|synapse|postsynaptic membrane|,protein phosphorylation|cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|axon guidance|axon guidance|adult walking behavior|motor neuron axon guidance|glial cell migration|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|corticospinal tract morphogenesis|regulation of Rac GTPase activity|regulation of Rap GTPase activity|regulation of Rho GTPase activity|positive regulation of JUN kinase activity|protein autophosphorylation|ephrin receptor signaling pathway|negative regulation of axon regeneration|negative regulation of axon regeneration|regulation of astrocyte differentiation|regulation of axonogenesis|positive regulation of dendrite morphogenesis|regulation of dendritic spine morphogenesis|fasciculation of sensory neuron axon|fasciculation of motor neuron axon|positive regulation of Rho guanyl-nucleotide exchange factor activity|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|GPI-linked ephrin receptor activity|transmembrane-ephrin receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|PH domain binding|identical protein binding|ephrin receptor binding|DH domain binding|",10,0.4,1.7,10,-0.2,0.814,0.3,1.21,1.21,0.606,0,0,-0.8,1.6
ENSMUSG00000063929,CYP4A32,"cytochrome P450, family 4, subfamily a, polypeptide 32",cytoplasm|apical plasma membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,leukotriene B4 catabolic process|oxidation-reduction process|,monooxygenase activity|arachidonic acid monooxygenase activity|arachidonic acid epoxygenase activity|oxidoreductase activity|alkane 1-monooxygenase activity|metal ion binding|leukotriene-B4 20-monooxygenase activity|,9,-0.2,0.527,9,-0.2,0.785,-0.2,1.21,-1.21,0.606,0,0,-1.6,1.2
ENSMUSG00000078816,PRKCG,"protein kinase C, gamma",nucleus|cytoplasm|cytosol|plasma membrane|plasma membrane|cell-cell junction|membrane|cell junction|dendrite|dendrite|cell projection|neuron projection|synapse|perinuclear region of cytoplasm|synaptic membrane|,protein phosphorylation|synaptic transmission|chemosensory behavior|phosphorylation|negative regulation of protein ubiquitination|positive regulation of mismatch repair|intracellular signal transduction|negative regulation of protein catabolic process|response to morphine|negative regulation of neuron apoptotic process|protein autophosphorylation|response to pain|innervation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|calcium-dependent protein kinase C activity|protein serine/threonine/tyrosine kinase activity|ATP binding|zinc ion binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.1,0.246,10,-0.2,1.83,-0.2,1.21,-1.21,0.606,0,0,-1.6,1
ENSMUSG00000028680,PLK3,polo-like kinase 3,intracellular|nucleus|nucleolus|cytoplasm|Golgi apparatus|Golgi stack|centrosome|cytoskeleton|dendrite|neuronal cell body|,cell cycle checkpoint|G1/S transition of mitotic cell cycle|mitotic S phase|negative regulation of transcription from RNA polymerase II promoter|response to reactive oxygen species|protein phosphorylation|protein phosphorylation|apoptotic process|response to osmotic stress|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|cell cycle|response to radiation|phosphorylation|cytoplasmic microtubule organization|negative regulation of apoptotic process|protein kinase B signaling|regulation of cell division|Golgi disassembly|positive regulation of intracellular protein transport|positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia|,"nucleotide binding|p53 binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1.2,4.36,10,-0.3,0.42,1.1,1.2,1.2,0.608,0,0,-0.4,2
ENSMUSG00000066735,VKORC1L1,"vitamin K epoxide reductase complex, subunit 1-like 1",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,peptidyl-glutamic acid carboxylation|cellular response to oxidative stress|vitamin K metabolic process|vitamin K metabolic process|oxidation-reduction process|,oxidoreductase activity|vitamin-K-epoxide reductase (warfarin-sensitive) activity|vitamin-K-epoxide reductase (warfarin-sensitive) activity|quinone binding|,9,0.5,1.49,9,-0.2,0.911,0.2,1.18,1.18,0.611,0,0,-0.9,1.8
ENSMUSG00000032380,DAPK2,death-associated protein kinase 2,cytoplasm|cytoplasm|cytoplasmic vesicle|,protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|phosphorylation|intracellular signal transduction|intracellular signal transduction|regulation of apoptotic process|anoikis|regulation of intrinsic apoptotic signaling pathway|regulation of intrinsic apoptotic signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin binding|calmodulin binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|",10,0,0,10,-0.7,3.39,-0.3,1.17,-1.17,0.613,0,0,-1.7,1.6
ENSMUSG00000032316,CLK3,CDC-like kinase 3,nucleus|nucleus|cytoplasm|membrane|cytoplasmic vesicle|intermediate filament cytoskeleton|,protein phosphorylation|protein phosphorylation|phosphorylation|peptidyl-tyrosine phosphorylation|regulation of RNA splicing|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|",10,0,0,10,0.4,3.04,0.3,1.17,1.17,0.613,0,0,-0.3,2
ENSMUSG00000039804,NCOA5,nuclear receptor coactivator 5,extracellular space|nucleus|actin cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",poly(A) RNA binding|,9,0.2,0.889,10,0.2,0.36,0.2,1.15,1.15,0.616,0,0,-1.7,1.1
ENSMUSG00000060882,KCND2,"potassium voltage-gated channel, Shal-related family, member 2",plasma membrane|integral component of plasma membrane|voltage-gated potassium channel complex|postsynaptic density|membrane|integral component of membrane|dendrite|potassium channel complex|cell projection|neuron projection|neuronal cell body|dendritic spine|dendritic spine|perinuclear endoplasmic reticulum|,action potential|action potential|transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|protein heterooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|A-type (transient outward) potassium channel activity|A-type (transient outward) potassium channel activity|potassium channel activity|protein binding|metal ion binding|protein heterodimerization activity|,10,0.3,2.52,10,-0.1,0.245,0.3,1.15,1.15,0.616,0,0,-1.2,1.4
ENSMUSG00000045318,ADRA2C,"adrenergic receptor, alpha 2c",cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|axon terminus|,regulation of smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|female pregnancy|regulation of vasoconstriction|platelet activation|activation of protein kinase B activity|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway|positive regulation of neuron differentiation|positive regulation of vasoconstriction|regulation of sensory perception of pain|negative regulation of uterine smooth muscle contraction|adrenergic receptor signaling pathway|activation of MAPK activity by adrenergic receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|alpha2-adrenergic receptor activity|alpha2-adrenergic receptor activity|alpha-2A adrenergic receptor binding|protein homodimerization activity|protein heterodimerization activity|epinephrine binding|,10,-1,2.1,10,-0.1,0.461,-0.2,1.14,-1.14,0.617,0,0,-2,0.4
ENSMUSG00000005672,KIT,kit oncogene,acrosomal vesicle|extracellular space|intracellular|cytoplasm|plasma membrane|cell-cell junction|external side of plasma membrane|external side of plasma membrane|cytoplasmic side of plasma membrane|cell surface|membrane|integral component of membrane|mast cell granule|,activation of MAPK activity|ovarian follicle development|myeloid progenitor cell differentiation|lymphoid progenitor cell differentiation|immature B cell differentiation|dendritic cell cytokine production|mast cell chemotaxis|myeloid leukocyte differentiation|protein phosphorylation|glycosphingolipid metabolic process|chemotaxis|inflammatory response|transmembrane receptor protein tyrosine kinase signaling pathway|germ cell development|spermatogenesis|spermatogenesis|spermatid development|positive regulation of cell proliferation|positive regulation of cell proliferation|germ cell migration|regulation of cell shape|visual learning|response to radiation|positive regulation of gene expression|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|lamellipodium assembly|hemopoiesis|cell differentiation|T cell differentiation|erythrocyte differentiation|melanocyte differentiation|positive regulation of cell migration|positive regulation of pseudopodium assembly|actin cytoskeleton reorganization|mast cell cytokine production|somatic stem cell maintenance|embryonic hemopoiesis|ectopic germ cell programmed cell death|intracellular signal transduction|megakaryocyte development|Fc receptor signaling pathway|Kit signaling pathway|Kit signaling pathway|erythropoietin-mediated signaling pathway|positive regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of programmed cell death|negative regulation of programmed cell death|mast cell degranulation|positive regulation of MAP kinase activity|positive regulation of MAPK cascade|pigmentation|pigmentation|positive regulation of Notch signaling pathway|positive regulation of JAK-STAT cascade|protein autophosphorylation|protein autophosphorylation|developmental pigmentation|regulation of developmental pigmentation|regulation of developmental pigmentation|somatic stem cell division|positive regulation of long-term neuronal synaptic plasticity|digestive tract development|stem cell differentiation|epithelial cell proliferation|detection of mechanical stimulus involved in sensory perception of sound|positive regulation of sequence-specific DNA binding transcription factor activity|cell chemotaxis|mast cell differentiation|cellular response to thyroid hormone stimulus|melanocyte migration|melanocyte adhesion|,"nucleotide binding|protease binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity|stem cell factor receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cytokine binding|protein homodimerization activity|metal ion binding|",10,-0.8,1.26,10,-0.2,1.07,-0.3,1.13,-1.13,0.618,0,0,-2,0.4
ENSMUSG00000028664,EPHB2,Eph receptor B2,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|dendrite|cell projection|neuronal cell body|synapse|,cell morphogenesis|angiogenesis|urogenital system development|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|axon guidance|axon guidance|axonal fasciculation|learning|organ morphogenesis|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|optic nerve morphogenesis|central nervous system projection neuron axonogenesis|corpus callosum development|retinal ganglion cell axon guidance|inner ear morphogenesis|ephrin receptor signaling pathway|ephrin receptor signaling pathway|regulation of neuronal synaptic plasticity|positive regulation of long-term neuronal synaptic plasticity|camera-type eye morphogenesis|regulation of axonogenesis|negative regulation of axonogenesis|regulation of body fluid levels|positive regulation of synapse assembly|positive regulation of synapse assembly|palate development|dendritic spine development|dendritic spine morphogenesis|commissural neuron axon guidance|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor activity|ephrin receptor activity|transmembrane-ephrin receptor activity|transmembrane-ephrin receptor activity|receptor binding|protein binding|ATP binding|axon guidance receptor activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|",10,0.1,0.434,10,0.3,0.953,0.2,1.13,1.13,0.618,0,0,-0.9,1.7
ENSMUSG00000056073,GRIK2,"glutamate receptor, ionotropic, kainate 2 (beta 2)",plasma membrane|integral component of plasma membrane|ionotropic glutamate receptor complex|ionotropic glutamate receptor complex|postsynaptic density|membrane|integral component of membrane|cell junction|axon|dendrite|dendrite|dendrite cytoplasm|kainate selective glutamate receptor complex|presynaptic membrane|neuronal cell body|terminal bouton|perikaryon|synapse|synapse|synapse|postsynaptic membrane|,"behavioral fear response|transport|ion transport|cellular calcium ion homeostasis|intracellular protein transport|signal transduction|synaptic transmission|synaptic transmission|synaptic transmission|neuronal action potential|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|regulation of membrane potential|regulation of membrane potential|regulation of membrane potential|receptor clustering|negative regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|regulation of JNK cascade|regulation of long-term neuronal synaptic plasticity|regulation of short-term neuronal synaptic plasticity|regulation of short-term neuronal synaptic plasticity|regulation of synaptic transmission|positive regulation of synaptic transmission|neuron apoptotic process|negative regulation of synaptic transmission, glutamatergic|negative regulation of synaptic transmission, glutamatergic|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|regulation of inhibitory postsynaptic membrane potential|regulation of inhibitory postsynaptic membrane potential|",receptor activity|ionotropic glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|glutamate receptor activity|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|kainate selective glutamate receptor activity|PDZ domain binding|ubiquitin conjugating enzyme binding|ubiquitin protein ligase binding|identical protein binding|protein homodimerization activity|,10,0.3,1.44,10,-0.6,2.27,-0.3,1.12,-1.12,0.62,0,0,-1.6,1.4
ENSMUSG00000027531,IMPA1,inositol (myo)-1(or 4)-monophosphatase 1,cytoplasm|axon|neuronal cell body|extracellular vesicular exosome|,inositol metabolic process|phosphatidylinositol biosynthetic process|phosphate-containing compound metabolic process|signal transduction|dephosphorylation|phosphatidylinositol phosphorylation|inositol phosphate dephosphorylation|,inositol monophosphate 1-phosphatase activity|hydrolase activity|identical protein binding|protein homodimerization activity|metal ion binding|inositol monophosphate 3-phosphatase activity|inositol monophosphate 4-phosphatase activity|inositol monophosphate phosphatase activity|,9,-0.2,0.00552,9,-0.3,1.47,-0.3,1.12,-1.12,0.62,0,0,-1.9,0.7
ENSMUSG00000021745,PTPRG,"protein tyrosine phosphatase, receptor type, G",extracellular space|membrane|integral component of membrane|extracellular vesicular exosome|,protein dephosphorylation|negative regulation of neuron projection development|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|identical protein binding|,10,-0.7,1.8,10,0.5,2.43,0.3,1.12,1.12,0.62,0,0,-1.6,1.4
ENSMUSG00000006127,INPP5K,inositol polyphosphate 5-phosphatase K,ruffle|nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|trans-Golgi network|cytosol|plasma membrane|membrane|membrane|ruffle membrane|neuron projection|perinuclear region of cytoplasm|,"in utero embryonic development|negative regulation of protein phosphorylation|regulation of glycogen biosynthetic process|negative regulation of protein kinase activity|G-protein coupled receptor signaling pathway|negative regulation of peptidyl-threonine phosphorylation|negative regulation of glucose transport|dephosphorylation|dephosphorylation|dephosphorylation|response to insulin|cellular response to insulin stimulus|cellular response to hormone stimulus|negative regulation of peptidyl-serine phosphorylation|negative regulation of peptidyl-serine phosphorylation|negative regulation of dephosphorylation|positive regulation of urine volume|glucose homeostasis|negative regulation of MAP kinase activity|negative regulation by host of viral transcription|negative regulation of glycogen biosynthetic process|negative regulation of glycogen biosynthetic process|negative regulation of single stranded viral RNA replication via double stranded DNA intermediate|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of insulin receptor signaling pathway|negative regulation of insulin receptor signaling pathway|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|phosphatidylinositol dephosphorylation|negative regulation of stress fiber assembly|negative regulation of protein kinase B signaling|negative regulation of protein kinase B signaling|negative regulation of calcium ion transport|cellular response to cAMP|cellular response to tumor necrosis factor|cellular response to epidermal growth factor stimulus|protein targeting to plasma membrane|negative regulation of protein targeting to membrane|ruffle assembly|negative regulation of glycogen (starch) synthase activity|positive regulation of renal water transport|","inositol-polyphosphate 5-phosphatase activity|vasopressin receptor activity|inositol bisphosphate phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity|phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity|phosphatidylinositol trisphosphate phosphatase activity|phosphatidylinositol phosphate 5-phosphatase activity|inositol trisphosphate phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity|",10,1.2,4.16,10,0,0,1.1,1.11,1.11,0.622,0,0,-0.5,2
ENSMUSG00000030269,MTMR14,myotubularin related protein 14,ruffle|cytoplasm|perinuclear region of cytoplasm|,dephosphorylation|,"phosphatidylinositol-3-phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0,0,10,0.2,1.26,0.2,1.11,1.11,0.622,0,0,-1.4,1.3
ENSMUSG00000035246,PCYT1B,"phosphate cytidylyltransferase 1, choline, beta isoform",endoplasmic reticulum|,ovarian follicle development|lipid metabolic process|spermatogenesis|phospholipid biosynthetic process|biosynthetic process|,catalytic activity|choline-phosphate cytidylyltransferase activity|transferase activity|nucleotidyltransferase activity|,10,-0.3,0.867,10,-0.3,0.303,-0.3,1.08,-1.08,0.626,0,0,-1.6,1.2
ENSMUSG00000030237,SLCO1A4,"solute carrier organic anion transporter family, member 1a4",plasma membrane|membrane|integral component of membrane|,transport|ion transport|anion transport|lipid transport|organic anion transport|bile acid and bile salt transport|ion transmembrane transport|sodium-independent organic anion transport|,transporter activity|organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|bile acid transmembrane transporter activity|,10,0.3,2.41,10,0,0,0.2,1.08,1.08,0.626,0,0,-0.8,1.7
ENSMUSG00000032936,CAMKV,CaM kinase-like vesicle-associated,cellular_component|plasma membrane|membrane|cytoplasmic vesicle|,protein phosphorylation|,"protein kinase activity|calmodulin binding|ATP binding|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.329,10,0.3,0.988,0.2,1.07,1.07,0.628,0,0,-1.8,1.1
ENSMUSG00000002007,SRPK3,serine/arginine-rich protein specific kinase 3,cellular_component|,protein phosphorylation|multicellular organismal development|muscle organ development|skeletal muscle tissue development|phosphorylation|cell differentiation|muscle tissue development|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0.2,0.359,9,0.2,0.797,0.2,1.06,1.06,0.63,0,0,-0.9,1.8
ENSMUSG00000022853,EHHADH,"enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase",nucleus|cytoplasm|mitochondrion|peroxisome|peroxisome|cytosol|intracellular membrane-bounded organelle|,internal protein amino acid acetylation|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|fatty acid beta-oxidation|acyl-CoA metabolic process|metabolic process|oxidation-reduction process|,"catalytic activity|3-hydroxyacyl-CoA dehydrogenase activity|3-hydroxyacyl-CoA dehydrogenase activity|dodecenoyl-CoA delta-isomerase activity|enoyl-CoA hydratase activity|receptor binding|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|lyase activity|isomerase activity|enzyme binding|coenzyme binding|",10,-0.2,0.241,10,-0.2,0.907,-0.2,1.06,-1.06,0.63,0,0,-1.4,1.3
ENSMUSG00000028141,OAZ3,ornithine decarboxylase antizyme 3,nucleus|nucleus|cytoplasm|cytoplasm|sperm flagellum|blood microparticle|,polyamine metabolic process|negative regulation of catalytic activity|negative regulation of catalytic activity|regulation of phosphoprotein phosphatase activity|,enzyme inhibitor activity|protein binding|ornithine decarboxylase inhibitor activity|ornithine decarboxylase inhibitor activity|ornithine decarboxylase inhibitor activity|ankyrin repeat binding|,10,0.5,2.42,10,-0.3,1.46,0.3,1.06,1.06,0.63,0,0,-1,1.6
ENSMUSG00000024640,PSAT1,phosphoserine aminotransferase 1,extracellular vesicular exosome|,L-serine biosynthetic process|metabolic process|cellular amino acid biosynthetic process|,catalytic activity|O-phospho-L-serine:2-oxoglutarate aminotransferase activity|transaminase activity|transferase activity|pyridoxal phosphate binding|,10,-0.4,1.33,10,0.4,3.1,0.3,1.05,1.05,0.631,0,0,-1.1,1.6
ENSMUSG00000025140,PYCR1,pyrroline-5-carboxylate reductase 1,mitochondrion|mitochondrion|,proline biosynthetic process|response to stress|cellular amino acid biosynthetic process|cellular response to oxidative stress|regulation of mitochondrial membrane potential|oxidation-reduction process|,pyrroline-5-carboxylate reductase activity|oxidoreductase activity|identical protein binding|,10,0,0,10,-0.4,1.64,-0.3,1.05,-1.05,0.631,0,0,-1.7,0.9
ENSMUSG00000027952,PMVK,phosphomevalonate kinase,cytoplasm|peroxisome|cytosol|membrane|extracellular vesicular exosome|,"lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|isoprenoid biosynthetic process|sterol biosynthetic process|phosphorylation|isopentenyl diphosphate biosynthetic process, mevalonate pathway|",nucleotide binding|phosphomevalonate kinase activity|phosphomevalonate kinase activity|ATP binding|kinase activity|transferase activity|,7,0.3,0.293,8,0.2,0.855,0.2,1.04,1.04,0.633,0,0,-1.1,1.8
ENSMUSG00000050890,PDIK1L,PDLIM1 interacting kinase 1 like,cellular_component|nucleus|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0.2,2.09,9,0,0,0.2,1.03,1.03,0.635,0,0,-0.9,1.8
ENSMUSG00000034353,RAMP1,receptor (calcitonin) activity modifying protein 1,extracellular space|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|,angiogenesis|transport|calcium ion transport|intracellular protein transport|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|protein transport|positive regulation of cAMP biosynthetic process|receptor internalization|positive regulation of protein glycosylation|protein localization to plasma membrane|,receptor activity|calcitonin receptor activity|protein transporter activity|coreceptor activity|coreceptor activity|calcitonin receptor binding|,10,-0.2,0.877,10,0.2,0.554,-0.1,1.02,-1.02,0.636,0,0,-1.6,1.1
ENSMUSG00000000560,GABRA2,"gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2",plasma membrane|membrane|integral component of membrane|cell junction|integral component of synaptic vesicle membrane|axon|dendrite membrane|chloride channel complex|synapse|postsynaptic membrane|,regulation of neurotransmitter levels|transport|ion transport|chloride transport|neurotransmitter transport|gamma-aminobutyric acid signaling pathway|,GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|chloride channel activity|benzodiazepine receptor activity|,10,0.2,0.445,10,0.1,0.693,0.2,1.02,1.02,0.636,0,0,-1,1.6
ENSMUSG00000096145,VKORC1,"vitamin K epoxide reductase complex, subunit 1",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,blood coagulation|blood coagulation|response to organonitrogen compound|response to organic cyclic compound|drug metabolic process|peptidyl-glutamic acid carboxylation|regulation of blood coagulation|vitamin K biosynthetic process|vitamin K metabolic process|vitamin K metabolic process|vitamin K metabolic process|response to antibiotic|positive regulation of coagulation|oxidation-reduction process|bone development|,oxidoreductase activity|vitamin-K-epoxide reductase (warfarin-sensitive) activity|vitamin-K-epoxide reductase (warfarin-sensitive) activity|vitamin-K-epoxide reductase (warfarin-sensitive) activity|vitamin-K-epoxide reductase (warfarin-sensitive) activity|vitamin-K-epoxide reductase (warfarin-insensitive) activity|quinone binding|,10,0,0,10,0.2,1.61,0.2,1.01,1.01,0.637,0,0,-0.6,1.9
ENSMUSG00000030730,ATP2A1,"ATPase, Ca++ transporting, cardiac muscle, fast twitch 1",mitochondrion|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|H zone|I band|intracellular membrane-bounded organelle|,ATP catabolic process|transport|ion transport|cation transport|calcium ion transport|regulation of muscle contraction|regulation of striated muscle contraction|apoptotic mitochondrial changes|organic anion transport|positive regulation of fast-twitch skeletal muscle fiber contraction|positive regulation of endoplasmic reticulum calcium ion concentration|negative regulation of endoplasmic reticulum calcium ion concentration|response to endoplasmic reticulum stress|response to peptide hormone|negative regulation of striated muscle contraction|positive regulation of mitochondrial calcium ion concentration|maintenance of mitochondrion location|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|sarcoplasmic reticulum calcium ion transport|calcium ion import|calcium ion transmembrane transport|relaxation of skeletal muscle|carbohydrate derivative transport|nucleotide transmembrane transport|,nucleotide binding|nucleotide-sugar transmembrane transporter activity|calcium-transporting ATPase activity|calcium ion binding|ATP binding|hydrolase activity|cation-transporting ATPase activity|protein homodimerization activity|metal ion binding|,10,-0.1,0.184,10,0.2,1.45,0.2,1.01,1.01,0.637,0,0,-1.1,1.6
ENSMUSG00000028518,PRKAA2,"protein kinase, AMP-activated, alpha 2 catalytic subunit",nucleus|cytoplasm|apical plasma membrane|AMP-activated protein kinase complex|protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|steroid biosynthetic process|cholesterol biosynthetic process|autophagy|response to stress|steroid metabolic process|cholesterol metabolic process|lipid biosynthetic process|positive regulation of autophagy|response to activity|Wnt signaling pathway|sterol biosynthetic process|phosphorylation|chromatin modification|regulation of lipid metabolic process|response to caffeine|cellular response to nutrient levels|negative regulation of TOR signaling|histone-serine phosphorylation|cellular response to glucose starvation|glucose homeostasis|regulation of circadian rhythm|negative regulation of apoptotic process|positive regulation of glycolytic process|rhythmic process|protein heterooligomerization|fatty acid homeostasis|regulation of energy homeostasis|","nucleotide binding|chromatin binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|AMP-activated protein kinase activity|AMP-activated protein kinase activity|AMP-activated protein kinase activity|AMP-activated protein kinase activity|protein serine/threonine/tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein binding, bridging|histone serine kinase activity|metal ion binding|[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity|[acetyl-CoA carboxylase] kinase activity|",10,-0.1,0.0358,10,-0.3,1.85,-0.2,1.01,-1.01,0.637,0,0,-1.8,0.8
ENSMUSG00000014602,KIF1A,kinesin family member 1A,cytoplasm|cytoskeleton|kinesin complex|microtubule|neuron projection|neuronal cell body|,microtubule-based movement|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|,9,0.2,0.0743,9,-0.4,2.89,-0.3,0.999,-0.999,0.639,0,0,-1.7,1
ENSMUSG00000017064,PRL5A1,"prolactin family 5, subfamily a, member 1",cellular_component|extracellular region|,biological_process|,molecular_function|hormone activity|,10,-1,2.94,10,0.5,3.25,0.2,0.998,0.998,0.639,0,0,-2,1.1
ENSMUSG00000033502,CDC14A,CDC14 cell division cycle 14A,nucleus|cytoplasm|centrosome|cytoskeleton|,protein dephosphorylation|cell cycle|dephosphorylation|cell division|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,-0.2,0.678,10,-0.2,0.39,-0.2,0.982,-0.982,0.642,0,0,-1.8,0.8
ENSMUSG00000030861,ACADSB,"acyl-Coenzyme A dehydrogenase, short/branched chain",mitochondrion|mitochondrion|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|acyl-CoA metabolic process|metabolic process|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|electron carrier activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|short-branched-chain-acyl-CoA dehydrogenase activity|flavin adenine dinucleotide binding|",8,-0.2,0.752,8,-0.1,0.393,-0.2,0.954,-0.954,0.647,0,0,-1.7,1.2
ENSMUSG00000045934,MTMR11,myotubularin related protein 11,cellular_component|,biological_process|dephosphorylation|,molecular_function|phosphatase activity|,10,0.2,0.816,10,0.1,0.326,0.2,0.95,0.95,0.647,0,0,-0.7,1.8
ENSMUSG00000007050,LSM2,"LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)",nucleus|spliceosomal complex|cytoplasm|ribonucleoprotein complex|U4/U6 x U5 tri-snRNP complex|catalytic step 2 spliceosome|,spliceosomal tri-snRNP complex assembly|mRNA processing|mRNA catabolic process|RNA splicing|,RNA binding|protein binding|protein kinase binding|poly(A) RNA binding|,4,0.6,1.31,4,-0.2,0.129,0.4,0.936,0.936,0.65,0,0,-1.2,2
ENSMUSG00000042608,STK40,serine/threonine kinase 40,nucleus|cytoplasm|,respiratory system process|glycogen metabolic process|protein phosphorylation|regulation of gene expression|phosphorylation|lung development|multicellular organism growth|negative regulation of apoptotic process|regulation of MAPK cascade|lung alveolus development|lung morphogenesis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1,4.04,10,0,0,1,0.928,0.928,0.651,0,0,-0.6,2
ENSMUSG00000024225,CLPS,"colipase, pancreatic",extracellular region|extracellular vesicular exosome|,lipid metabolic process|digestion|lipid catabolic process|positive regulation of catalytic activity|,enzyme activator activity|,9,-0.5,1.33,9,0.1,0.0176,-0.5,0.923,-0.923,0.652,0,0,-1.6,1.1
ENSMUSG00000028927,PADI2,"peptidyl arginine deiminase, type II",cytoplasm|transcriptionally active chromatin|extracellular vesicular exosome|,cellular protein modification process|regulation of chromatin disassembly|protein citrullination|intracellular estrogen receptor signaling pathway|histone H3-R26 citrullination|chromatin-mediated maintenance of transcription|negative regulation of chemokine-mediated signaling pathway|negative regulation of lymphocyte chemotaxis|,protein-arginine deiminase activity|calcium ion binding|hydrolase activity|estrogen receptor binding|,10,-0.1,0.413,10,-0.2,0.6,-0.2,0.91,-0.91,0.654,0,0,-1.6,1
ENSMUSG00000032537,EPHB1,Eph receptor B1,cytoplasm|endosome|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|early endosome membrane|cell projection|membrane raft|extracellular vesicular exosome|,angiogenesis|protein phosphorylation|cell adhesion|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|axon guidance|axon guidance|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cranial nerve development|optic nerve morphogenesis|central nervous system projection neuron axonogenesis|central nervous system projection neuron axonogenesis|neurogenesis|establishment of cell polarity|retinal ganglion cell axon guidance|cell-substrate adhesion|regulation of JNK cascade|protein autophosphorylation|ephrin receptor signaling pathway|ephrin receptor signaling pathway|camera-type eye morphogenesis|detection of temperature stimulus involved in sensory perception of pain|positive regulation of synapse assembly|cell chemotaxis|cell chemotaxis|dendritic spine development|dendritic spine morphogenesis|neural precursor cell proliferation|regulation of ERK1 and ERK2 cascade|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|transmembrane-ephrin receptor activity|transmembrane-ephrin receptor activity|protein binding|ATP binding|axon guidance receptor activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.446,10,0.2,0.543,0.2,0.908,0.908,0.655,0,0,-0.8,1.9
ENSMUSG00000061950,PPP4R1,"protein phosphatase 4, regulatory subunit 1",cellular_component|,biological_process|,molecular_function|,9,0.2,1.45,9,0,0,0.2,0.905,0.905,0.655,0,0,-0.8,1.9
ENSMUSG00000030433,SBK2,"SH3-binding domain kinase family, member 2",None,protein phosphorylation|phosphorylation|signal transduction by phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.5,2.5,10,0,0,0.4,0.905,0.905,0.655,0,0,-0.7,1.8
ENSMUSG00000030223,PTPRO,"protein tyrosine phosphatase, receptor type, O",plasma membrane|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|dendritic spine|extracellular vesicular exosome|,cell morphogenesis|monocyte chemotaxis|regulation of glomerular filtration|negative regulation of glomerular filtration|protein dephosphorylation|axon guidance|dephosphorylation|lamellipodium assembly|glomerulus development|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|slit diaphragm assembly|glomerular visceral epithelial cell differentiation|negative regulation of canonical Wnt signaling pathway|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|Wnt-protein binding|protein homodimerization activity|,10,0.3,0.561,10,0.2,0.502,0.2,0.904,0.904,0.655,0,0,-0.8,1.7
ENSMUSG00000061603,AKAP6,A kinase (PRKA) anchor protein 6,nucleus|nuclear envelope|nuclear envelope|nuclear outer membrane|cytoplasm|caveola|junctional sarcoplasmic reticulum membrane|junctional sarcoplasmic reticulum membrane|intercalated disc|sarcoplasmic reticulum|T-tubule|nuclear membrane|calcium channel complex|calcium channel complex|sarcolemma|protein complex|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,positive regulation of protein phosphorylation|regulation of protein kinase A signaling|phosphorylation|positive regulation of cell growth|negative regulation of cAMP biosynthetic process|positive regulation of protein phosphatase type 2B activity|cellular protein complex localization|positive regulation of release of sequestered calcium ion into cytosol|positive regulation of NFAT protein import into nucleus|regulation of membrane repolarization|positive regulation of ryanodine-sensitive calcium-release channel activity|positive regulation of cell growth involved in cardiac muscle cell development|positive regulation of calcineurin-NFAT signaling cascade|cellular response to cAMP|cellular response to cytokine stimulus|cellular response to epinephrine stimulus|regulation of cardiac muscle cell contraction|positive regulation of potassium ion transmembrane transport|regulation of relaxation of cardiac muscle|positive regulation of delayed rectifier potassium channel activity|positive regulation of cAMP-dependent protein kinase activity|,adenylate cyclase binding|kinase activity|transferase activity|enzyme binding|protein complex scaffold|protein kinase A regulatory subunit binding|protein anchor|ion channel binding|protein N-terminus binding|protein kinase A binding|protein phosphatase 2A binding|,10,0,0,10,-0.3,2.36,-0.2,0.903,-0.903,0.656,0,0,-1.8,0.7
ENSMUSG00000073418,C4B,complement component 4B (Chido blood group),extracellular region|extracellular space|extracellular space|other organism cell|extracellular vesicular exosome|blood microparticle|,complement activation|immunoglobulin mediated immune response|,complement binding|complement component C1q binding|carbohydrate binding|,10,0.3,0.835,10,-0.1,0.848,0.3,0.902,0.902,0.656,0,0,-0.8,1.8
ENSMUSG00000032271,NNMT,nicotinamide N-methyltransferase,cytoplasm|cytosol|,methylation|,nicotinamide N-methyltransferase activity|methyltransferase activity|transferase activity|,10,-0.4,0.63,10,-0.1,0.531,-0.1,0.902,-0.902,0.656,0,0,-1.8,0.8
ENSMUSG00000025417,PIP4K2C,"phosphatidylinositol-5-phosphate 4-kinase, type II, gamma",cytoplasm|endoplasmic reticulum|membrane|extracellular vesicular exosome|,phosphorylation|phosphatidylinositol metabolic process|phosphatidylinositol phosphorylation|,nucleotide binding|ATP binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|1-phosphatidylinositol-5-phosphate 4-kinase activity|transferase activity|identical protein binding|,10,0,0,10,0.5,2.52,0.3,0.896,0.896,0.657,0,0,-1.3,1.6
ENSMUSG00000035769,XYLB,xylulokinase homolog (H. influenzae),extracellular vesicular exosome|,carbohydrate metabolic process|xylulose metabolic process|phosphorylation|D-xylose metabolic process|carbohydrate phosphorylation|,"nucleotide binding|xylulokinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|",9,1.3,3.69,9,0.1,0.306,0.1,0.896,0.896,0.657,0,0,-0.6,2
ENSMUSG00000006235,EPOR,erythropoietin receptor,extracellular region|plasma membrane|membrane|integral component of membrane|,heart morphogenesis|signal transduction|positive regulation of cytosolic calcium ion concentration|brain development|heart development|embryo development|viral process|erythropoietin-mediated signaling pathway|erythropoietin-mediated signaling pathway|negative regulation of neuron apoptotic process|decidualization|cardiac muscle tissue morphogenesis|ventricular cardiac muscle tissue morphogenesis|vasculogenesis involved in coronary vascular morphogenesis|visceral serous pericardium development|,transmembrane signaling receptor activity|cytokine receptor activity|erythropoietin receptor activity|erythropoietin receptor activity|protein binding|identical protein binding|,10,-0.2,1.35,10,0.1,0.26,-0.2,0.896,-0.896,0.657,0,0,-1.1,1.5
ENSMUSG00000025531,CHM,choroidermia,cytoplasm|cytosol|Rab-protein geranylgeranyltransferase complex|,blood vessel development|protein targeting to membrane|intracellular protein transport|protein geranylgeranylation|,Rab geranylgeranyltransferase activity|GTPase activator activity|Rab GTPase binding|,10,-0.4,2.46,10,0,0,-0.2,0.879,-0.879,0.66,0,0,-1.7,0.9
ENSMUSG00000027333,SMOX,spermine oxidase,nucleus|cytoplasm|,polyamine catabolic process|spermine catabolic process|spermine catabolic process|oxidation-reduction process|oxidation-reduction process|,oxidoreductase activity|polyamine oxidase activity|polyamine oxidase activity|norspermine:oxygen oxidoreductase activity|N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity|spermine:oxygen oxidoreductase (spermidine-forming) activity|,10,0.3,1.9,10,0,0,0.2,0.875,0.875,0.661,0,0,-0.9,1.7
ENSMUSG00000037852,CPE,carboxypeptidase E,extracellular region|extracellular space|Golgi apparatus|membrane|secretory granule|dendrite|secretory granule membrane|dense core granule|cytoplasmic vesicle|neuronal cell body|perikaryon|membrane raft|extracellular vesicular exosome|synaptic membrane|,cardiac left ventricle morphogenesis|proteolysis|peptide metabolic process|protein processing|insulin processing|insulin processing|enkephalin processing|peptide catabolic process|protein localization to membrane|negative regulation of branching morphogenesis of a nerve|,carboxypeptidase activity|carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|protein domain specific binding|neurexin family protein binding|metal ion binding|cell adhesion molecule binding|cobalt ion binding|,10,0.2,0.857,10,0.1,0.198,0.2,0.87,0.87,0.662,0,0,-1,1.6
ENSMUSG00000067231,CYP2C65,"cytochrome P450, family 2, subfamily c, polypeptide 65",intracellular membrane-bounded organelle|,oxidation-reduction process|,monooxygenase activity|drug binding|testosterone 16-alpha-hydroxylase activity|steroid hydroxylase activity|oxidoreductase activity|caffeine oxidase activity|metal ion binding|,10,0.4,1.91,10,-0.2,1.44,-0.2,0.845,-0.845,0.666,0,0,-1.2,1.5
ENSMUSG00000024500,PPP2R2B,"protein phosphatase 2, regulatory subunit B, beta",protein phosphatase type 2A complex|cytoplasm|mitochondrion|mitochondrial outer membrane|cytosol|cytoskeleton|membrane|,mitochondrial fission|protein targeting to mitochondrion|apoptotic process|signal transduction|regulation of protein phosphatase type 2A activity|positive regulation of neuron apoptotic process|mitochondrial fragmentation involved in apoptotic process|,protein phosphatase type 2A regulator activity|protein complex binding|,10,0.3,2.1,10,0,0,0.2,0.837,0.837,0.667,0,0,-1,1.6
ENSMUSG00000046794,PPP1R3B,"protein phosphatase 1, regulatory (inhibitor) subunit 3B",protein phosphatase type 1 complex|glycogen granule|intracellular membrane-bounded organelle|,carbohydrate metabolic process|glycogen metabolic process|regulation of glycogen biosynthetic process|regulation of glycogen catabolic process|dephosphorylation|regulation of catalytic activity|,phosphoprotein phosphatase activity|protein phosphatase regulator activity|enzyme binding|,9,-0.6,1.3,9,-0.1,0.372,-0.2,0.833,-0.833,0.668,0,0,-1.9,0.8
ENSMUSG00000029082,BST1,bone marrow stromal cell antigen 1,plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,None,NAD+ nucleosidase activity|transferase activity|hydrolase activity|NAD(P)+ nucleosidase activity|,9,0.2,1.48,9,0,0,0.1,0.832,0.832,0.668,0,0,-1.2,1.6
ENSMUSG00000055471,ALK,anaplastic lymphoma kinase,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|protein complex|cell body|extracellular vesicular exosome|,activation of MAPK activity|protein phosphorylation|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|protein autophosphorylation|neuron development|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.4,1.68,10,-0.1,0.0185,-0.2,0.829,-0.829,0.669,0,0,-1.7,0.7
ENSMUSG00000015889,LTA4H,leukotriene A4 hydrolase,nucleus|cytoplasm|extracellular vesicular exosome|,proteolysis|leukotriene metabolic process|leukotriene biosynthetic process|peptide catabolic process|,aminopeptidase activity|epoxide hydrolase activity|leukotriene-A4 hydrolase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|poly(A) RNA binding|metal ion binding|,9,0,0,9,0.2,1.29,0.2,0.826,0.826,0.67,0,0,-1,1.8
ENSMUSG00000000766,OPRM1,"opioid receptor, mu 1",cytoplasm|plasma membrane|focal adhesion|membrane|membrane|integral component of membrane|dendrite|dendrite membrane|dendrite cytoplasm|sarcolemma|perikaryon|membrane raft|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|locomotory behavior|locomotory behavior|sensory perception of pain|adenylate cyclase-inhibiting opioid receptor signaling pathway|positive regulation of appetite|cellular response to stress|opioid receptor signaling pathway|opioid receptor signaling pathway|positive regulation of cAMP-mediated signaling|negative regulation of cAMP-mediated signaling|negative regulation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthetic process|response to ethanol|behavioral response to ethanol|positive regulation of neurogenesis|negative regulation of cytosolic calcium ion concentration|regulation of sensory perception of pain|regulation of excitatory postsynaptic membrane potential|negative regulation of Wnt protein secretion|positive regulation of ERK1 and ERK2 cascade|calcium ion transmembrane transport|cellular response to morphine|regulation of N-methyl-D-aspartate selective glutamate receptor activity|,G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|beta-endorphin receptor activity|opioid receptor activity|voltage-gated calcium channel activity|protein binding|protein domain specific binding|filamin binding|G-protein beta-subunit binding|morphine receptor activity|,10,-0.2,0.255,10,0.5,2.25,0.2,0.818,0.818,0.671,0,0,-0.9,1.8
ENSMUSG00000018893,MB,myoglobin,None,response to hypoxia|transport|heart development|response to hormone|oxygen transport|response to hydrogen peroxide|enucleate erythrocyte differentiation|brown fat cell differentiation|,oxygen transporter activity|iron ion binding|oxygen binding|heme binding|metal ion binding|,9,-0.1,0.192,9,0.3,2.03,0.3,0.813,0.813,0.672,0,0,-1.2,1.8
ENSMUSG00000019368,SEC14L4,SEC14-like 4 (S. cerevisiae),cellular_component|intracellular|integral component of membrane|,transport|,molecular_function|transporter activity|lipid binding|,10,-0.1,0.159,10,0.2,1.21,0.2,0.809,0.809,0.673,0,0,-1.2,1.5
ENSMUSG00000024084,QPCT,glutaminyl-peptide cyclotransferase (glutaminyl cyclase),extracellular region|extracellular vesicular exosome|,"peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase|","zinc ion binding|glutaminyl-peptide cyclotransferase activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,-0.4,1.73,10,0,0,-0.2,0.802,-0.802,0.674,0,0,-1.8,0.7
ENSMUSG00000001999,BLVRA,biliverdin reductase A,cytoplasm|extracellular vesicular exosome|,heme catabolic process|oxidation-reduction process|oxidation-reduction process|,nucleotide binding|biliverdin reductase activity|biliverdin reductase activity|zinc ion binding|oxidoreductase activity|metal ion binding|,9,-0.2,0.681,9,0.1,0.251,-0.2,0.796,-0.796,0.675,0,0,-1.5,1.4
ENSMUSG00000058620,ADRA2B,"adrenergic receptor, alpha 2b",intracellular|plasma membrane|membrane|integral component of membrane|,MAPK cascade|activation of MAPK activity|angiogenesis|regulation of vascular smooth muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|female pregnancy|activation of protein kinase B activity|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway|positive regulation of neuron differentiation|positive regulation of blood pressure|positive regulation of uterine smooth muscle contraction|adrenergic receptor signaling pathway|activation of MAPK activity by adrenergic receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|alpha2-adrenergic receptor activity|alpha2-adrenergic receptor activity|epinephrine binding|,10,0.1,0.104,10,-0.3,2.51,-0.2,0.792,-0.792,0.676,0,0,-1.7,0.9
ENSMUSG00000001794,CAPNS1,"calpain, small subunit 1",cytoplasm|cytosol|plasma membrane|membrane|extracellular vesicular exosome|,proteolysis|proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|metal ion binding|protein heterodimerization activity|,10,0.3,0.858,10,0.1,0.113,0.2,0.79,0.79,0.676,0,0,-0.8,1.8
ENSMUSG00000035441,MYO1D,myosin ID,smooth endoplasmic reticulum|myosin complex|axolemma|extracellular vesicular exosome|,ATP catabolic process|metabolic process|negative regulation of phosphatase activity|,microfilament motor activity|nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|actin-dependent ATPase activity|calcium-dependent protein binding|,10,-0.9,3.02,10,-0.1,0.504,-0.1,0.79,-0.79,0.676,0,0,-2,0.6
ENSMUSG00000044201,CDC25C,cell division cycle 25C,intracellular|nucleus|nucleus|cytoplasm|perinuclear region of cytoplasm|,G2/M transition of mitotic cell cycle|mitotic M phase|protein dephosphorylation|cell cycle|mitotic nuclear division|cell division|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|protein kinase binding|WW domain binding|,10,-0.1,0.533,10,-0.5,1.47,-0.2,0.788,-0.788,0.677,0,0,-1.7,0.8
ENSMUSG00000090100,TTBK2,tau tubulin kinase 2,extracellular space|nucleus|centriole|cytosol|,peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|,protein serine/threonine kinase activity|protein serine/threonine kinase activity|,10,0.1,0.0167,10,0.2,1.03,0.2,0.788,0.788,0.677,0,0,-1.4,1.4
ENSMUSG00000053664,UCK2,uridine-cytidine kinase 2,cytosol|intracellular membrane-bounded organelle|,metabolic process|nucleotide biosynthetic process|phosphorylation|,nucleotide binding|uridine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|nucleoside kinase activity|,4,0.5,2.16,4,-0.1,0.131,0.4,0.784,0.784,0.677,0,0,-1.2,2
ENSMUSG00000031491,CHRNA6,"cholinergic receptor, nicotinic, alpha polypeptide 6",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,transport|ion transport|cation transport|regulation of dopamine secretion|positive regulation of dopamine secretion|ion transmembrane transport|protein heterooligomerization|membrane depolarization|,acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|drug binding|,10,0,0,10,-0.2,0.995,-0.2,0.781,-0.781,0.678,0,0,-1.7,0.9
ENSMUSG00000061207,STK19,serine/threonine kinase 19,cellular_component|nucleus|,biological_process|phosphorylation|,nucleotide binding|molecular_function|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|,10,-0.1,0.246,10,-0.1,0.602,-0.1,0.779,-0.779,0.678,0,0,-1.7,1.1
ENSMUSG00000005949,CTNS,"cystinosis, nephropathic",lysosome|lysosome|lysosomal membrane|late endosome|plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|intermediate filament cytoskeleton|extracellular vesicular exosome|,lens development in camera-type eye|glutathione metabolic process|transport|brain development|long-term memory|grooming behavior|adult walking behavior|visual learning|L-cystine transport|L-cystine transport|L-cystine transport|ATP metabolic process|cognition|L-alpha-amino acid transmembrane transport|,L-cystine transmembrane transporter activity|L-cystine transmembrane transporter activity|L-cystine transmembrane transporter activity|,10,0.2,0.451,10,0.1,0.408,0.2,0.779,0.779,0.678,0,0,-1,1.6
ENSMUSG00000019762,IYD,iodotyrosine deiodinase,cellular_component|membrane|integral component of membrane|,oxidation-reduction process|,iodide peroxidase activity|iodide peroxidase activity|oxidoreductase activity|,10,0.2,0.271,10,-0.3,0.741,-0.2,0.778,-0.778,0.678,0,0,-1.6,1
ENSMUSG00000020051,PAH,phenylalanine hydroxylase,extracellular vesicular exosome|,L-phenylalanine metabolic process|L-phenylalanine catabolic process|tyrosine biosynthetic process|metabolic process|aromatic amino acid family metabolic process|protein hydroxylation|pteridine-containing compound metabolic process|tetrahydrobiopterin metabolic process|oxidation-reduction process|,"catalytic activity|monooxygenase activity|phenylalanine 4-monooxygenase activity|phenylalanine 4-monooxygenase activity|iron ion binding|oxidoreductase activity|amino acid binding|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen|protein homodimerization activity|metal ion binding|cofactor binding|",10,0,0,10,-0.4,2.31,-0.3,0.776,-0.776,0.679,0,0,-1.7,0.9
ENSMUSG00000021552,GKAP1,G kinase anchoring protein 1,Golgi apparatus|,signal transduction|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|,protein binding|,10,-0.2,1.1,10,0,0,-0.2,0.773,-0.773,0.679,0,0,-1.7,1.1
ENSMUSG00000029279,BRDT,"bromodomain, testis-specific",nucleus|,"histone displacement|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|meiotic nuclear division|male meiosis|male meiosis I|spermatogenesis|RNA splicing|chromatin modification|cell differentiation|regulation of RNA splicing|positive regulation of transcription during meiosis|",protein binding|histone binding|histone binding|lysine-acetylated histone binding|,10,0.5,1.82,10,0.1,0.0241,0.2,0.772,0.772,0.679,0,0,-0.6,1.9
ENSMUSG00000035232,PDK3,"pyruvate dehydrogenase kinase, isoenzyme 3",mitochondrion|,carbohydrate metabolic process|glucose metabolic process|regulation of acetyl-CoA biosynthetic process from pyruvate|regulation of glucose metabolic process|phosphorylation|peptidyl-serine phosphorylation|peroxisome proliferator activated receptor signaling pathway|cellular response to glucose stimulus|cellular response to fatty acid|hypoxia-inducible factor-1alpha signaling pathway|regulation of reactive oxygen species metabolic process|,nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|pyruvate dehydrogenase (acetyl-transferring) kinase activity|ATP binding|kinase activity|transferase activity|,10,-0.4,0.469,10,0.1,0.529,-0.6,0.761,-0.761,0.682,0,0,-1.9,0.8
ENSMUSG00000017291,TAOK1,TAO kinase 1,cytoplasm|extracellular vesicular exosome|,MAPK cascade|activation of MAPKK activity|DNA repair|protein phosphorylation|protein phosphorylation|apoptotic process|cellular response to DNA damage stimulus|phosphorylation|G2 DNA damage checkpoint|positive regulation of stress-activated MAPK cascade|positive regulation of protein kinase activity|positive regulation of JNK cascade|regulation of cytoskeleton organization|execution phase of apoptosis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein kinase activator activity|",9,0.5,1.1,10,0,0,0.2,0.758,0.758,0.682,0,0,-0.6,1.9
ENSMUSG00000037514,PANK2,pantothenate kinase 2,mitochondrion|mitochondrion|cytosol|,spermatid development|aerobic respiration|coenzyme A biosynthetic process|phosphorylation|regulation of mitochondrial membrane potential|mitochondrion morphogenesis|,pantothenate kinase activity|pantothenate kinase activity|pantothenate kinase activity|kinase activity|transferase activity|,10,0,0,10,-0.2,1.08,0.2,0.756,0.756,0.683,0,0,-1.2,1.5
ENSMUSG00000022483,COL2A1,"collagen, type II, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type II trimer|collagen type II trimer|collagen type II trimer|basement membrane|extracellular space|cytoplasm|cytoplasm|extracellular matrix|,skeletal system development|cartilage condensation|tissue homeostasis|endochondral ossification|chondrocyte differentiation|heart morphogenesis|proteoglycan metabolic process|visual perception|sensory perception of sound|regulation of gene expression|collagen fibril organization|collagen fibril organization|limb morphogenesis|inner ear morphogenesis|skeletal system morphogenesis|inner ear development|cartilage development|palate development|embryonic skeletal joint morphogenesis|bone development|cartilage development involved in endochondral bone morphogenesis|cellular response to BMP stimulus|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,extracellular matrix structural constituent|identical protein binding|metal ion binding|platelet-derived growth factor binding|,10,-0.2,0.602,9,-0.2,0.22,-0.2,0.755,-0.755,0.683,0,0,-1.6,1.2
ENSMUSG00000037628,CDKN3,cyclin-dependent kinase inhibitor 3,cytoplasm|perinuclear region of cytoplasm|,cell cycle|cell cycle arrest|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,9,0.1,0.293,9,-0.8,3.49,-0.1,0.748,-0.748,0.685,0,0,-2,0.5
ENSMUSG00000058017,SERPINB3D,"serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D",extracellular region|nucleus|extracellular vesicular exosome|,response to virus|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|negative regulation of catalytic activity|negative regulation of proteolysis|,virus receptor activity|serine-type endopeptidase inhibitor activity|,10,-0.2,0.748,10,0.5,3.1,0.3,0.742,0.742,0.686,0,0,-0.8,1.8
ENSMUSG00000023044,CSAD,cysteine sulfinic acid decarboxylase,cellular_component|,L-cysteine catabolic process to taurine|taurine metabolic process|carboxylic acid metabolic process|,catalytic activity|sulfinoalanine decarboxylase activity|lyase activity|carboxy-lyase activity|pyridoxal phosphate binding|,10,0.5,0.842,10,0.3,0.213,0.4,0.73,0.73,0.688,0,0,-0.6,1.9
ENSMUSG00000022472,DESI1,desumoylating isopeptidase 1,cellular_component|nucleus|cytoplasm|,proteolysis|biological_process|,protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|identical protein binding|,10,0.2,1.32,10,-0.2,0.74,0.2,0.729,0.729,0.689,0,0,-0.9,1.8
ENSMUSG00000029762,AKR1B8,"aldo-keto reductase family 1, member B8",cytoplasm|extracellular vesicular exosome|,farnesol catabolic process|daunorubicin metabolic process|doxorubicin metabolic process|oxidation-reduction process|,retinal dehydrogenase activity|alditol:NADP+ 1-oxidoreductase activity|oxidoreductase activity|geranylgeranyl reductase activity|indanol dehydrogenase activity|,10,-0.1,0.0548,10,0.7,2.25,0.2,0.725,0.725,0.69,0,0,-0.5,2
ENSMUSG00000024107,LHCGR,luteinizing hormone/choriogonadotropin receptor,extracellular space|nucleus|cytoplasm|lysosome|endosome|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|intrinsic component of external side of plasma membrane|receptor complex|,ovarian follicle development|protein targeting to lysosome|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|activation of adenylate cyclase activity|phospholipase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|spermatogenesis|male gonad development|female gonad development|hormone-mediated signaling pathway|positive regulation of calcium ion transport into cytosol|ovulation cycle process|positive regulation of inositol trisphosphate biosynthetic process|luteinizing hormone signaling pathway|luteinizing hormone signaling pathway|positive regulation of cAMP-mediated signaling|development of secondary male sexual characteristics|positive regulation of hormone biosynthetic process|arachidonic acid secretion|positive regulation of calcium-mediated signaling|cognition|positive regulation of release of sequestered calcium ion into cytosol|uterus development|cellular response to gonadotropin stimulus|seminiferous tubule development|regulation of steroid hormone biosynthetic process|,signal transducer activity|G-protein coupled receptor activity|luteinizing hormone receptor activity|G-protein coupled peptide receptor activity|protein-hormone receptor activity|peptide hormone binding|choriogonadotropin hormone receptor activity|choriogonadotropin hormone receptor activity|choriogonadotropin hormone binding|identical protein binding|protein homodimerization activity|ATPase binding|,10,-0.3,1.61,10,0.2,0.685,-0.2,0.723,-0.723,0.69,0,0,-1.5,1.3
ENSMUSG00000019178,STYXL1,serine/threonine/tyrosine interacting-like 1,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.62,10,0.4,1.9,-0.3,0.722,-0.722,0.69,0,0,-1.3,1.7
ENSMUSG00000028542,SLC6A9,"solute carrier family 6 (neurotransmitter transporter, glycine), member 9",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|neurotransmitter transport|amino acid transport|glycine transport|L-alpha-amino acid transmembrane transport|,sodium:amino acid symporter activity|neurotransmitter:sodium symporter activity|glycine transmembrane transporter activity|symporter activity|,10,-0.1,0.208,10,-0.1,0.578,-0.1,0.721,-0.721,0.69,0,0,-1.8,0.9
ENSMUSG00000005232,G6PC2,"glucose-6-phosphatase, catalytic, 2",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,gluconeogenesis|glucose homeostasis|regulation of insulin secretion|,catalytic activity|hydrolase activity|,10,-0.1,0.0937,10,-0.1,0.688,-0.1,0.72,-0.72,0.691,0,0,-1.5,1.3
ENSMUSG00000025013,TLL2,tolloid-like 2,extracellular region|,proteolysis|multicellular organismal development|cell differentiation|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.2,0.759,9,-0.1,0.215,-0.2,0.695,-0.695,0.696,0,0,-1.9,0.8
ENSMUSG00000048371,PDP2,pyruvate dehyrogenase phosphatase catalytic subunit 2,mitochondrion|mitochondrion|,protein dephosphorylation|peptidyl-threonine dephosphorylation|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|magnesium-dependent protein serine/threonine phosphatase activity|[pyruvate dehydrogenase (lipoamide)] phosphatase activity|hydrolase activity|metal ion binding|,10,0.3,2.2,10,-0.1,0.154,0.2,0.691,0.691,0.697,0,0,-1.3,1.3
ENSMUSG00000031387,RENBP,renin binding protein,extracellular vesicular exosome|,N-acetylglucosamine metabolic process|N-acetylglucosamine metabolic process|N-acetylmannosamine metabolic process|negative regulation of endopeptidase activity|N-acetylneuraminate catabolic process|negative regulation of catalytic activity|,catalytic activity|enzyme inhibitor activity|ATP binding|isomerase activity|purine nucleotide binding|protein homodimerization activity|N-acylglucosamine 2-epimerase activity|N-acylglucosamine 2-epimerase activity|N-acylglucosamine 2-epimerase activity|,10,-0.2,0.748,10,-0.1,0.122,-0.2,0.685,-0.685,0.698,0,0,-1.8,0.8
ENSMUSG00000031489,ADRB3,"adrenergic receptor, beta 3",nucleus|plasma membrane|membrane|integral component of membrane|receptor complex|,diet induced thermogenesis|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|response to cold|heat generation|negative regulation of multicellular organism growth|eating behavior|positive regulation of MAPK cascade|brown fat cell differentiation|adrenergic receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|beta-adrenergic receptor activity|beta3-adrenergic receptor activity|beta-3 adrenergic receptor binding|protein homodimerization activity|epinephrine binding|norepinephrine binding|norepinephrine binding|,10,-0.1,0.691,10,-0.1,0.0517,-0.1,0.684,-0.684,0.699,0,0,-1.7,1.1
ENSMUSG00000003746,MAN1A,"mannosidase 1, alpha",Golgi membrane|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,metabolic process|,"mannosyl-oligosaccharide 1,2-alpha-mannosidase activity|calcium ion binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|metal ion binding|",10,-0.2,0.393,10,-0.1,0.381,-0.1,0.667,-0.667,0.702,0,0,-1.4,1.3
ENSMUSG00000020736,NT5C,"5',3'-nucleotidase, cytosolic",nucleus|cytoplasm|mitochondrion|extracellular vesicular exosome|,nucleotide metabolic process|pyrimidine deoxyribonucleotide catabolic process|deoxyribonucleotide catabolic process|dephosphorylation|dephosphorylation|,"nucleotide binding|protein tyrosine/serine/threonine phosphatase activity|nucleotidase activity|5'-nucleotidase activity|5'-nucleotidase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|pyrimidine nucleotide binding|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|metal ion binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,-0.2,1.33,10,0,0,-0.2,0.662,-0.662,0.703,0,0,-1.7,1
ENSMUSG00000027365,TRPM7,"transient receptor potential cation channel, subfamily M, member 7",ruffle|cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|synaptic vesicle membrane|neuron projection|neuronal cell body|varicosity|,protein phosphorylation|protein phosphorylation|transport|ion transport|calcium ion transport|calcium ion transport|memory|cellular magnesium ion homeostasis|programmed cell death|phosphorylation|calcium-dependent cell-matrix adhesion|actomyosin structure organization|positive regulation of apoptotic process|protein autophosphorylation|transmembrane transport|necroptotic process|calcium ion transmembrane transport|,"nucleotide binding|actin binding|protein kinase activity|protein serine/threonine kinase activity|ion channel activity|cation channel activity|calcium channel activity|calcium channel activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|myosin binding|metal ion binding|",10,-0.2,0.727,10,-0.1,0.262,-0.1,0.662,-0.662,0.703,0,0,-1.7,0.9
ENSMUSG00000023262,ACY1,aminoacylase 1,cytoplasm|extracellular vesicular exosome|,proteolysis|cellular amino acid metabolic process|metabolic process|,aminoacylase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,9,1.2,3.14,9,0.2,0.539,1.1,0.662,0.662,0.703,0,0,-0.3,2
ENSMUSG00000032599,IP6K2,inositol hexaphosphate kinase 2,nucleus|nucleus|intermediate filament cytoskeleton|,phosphate ion transport|phosphorylation|negative regulation of cell growth|positive regulation of apoptotic process|phosphatidylinositol phosphorylation|,"nucleotide binding|inositol hexakisphosphate 5-kinase activity|ATP binding|inositol-1,4,5-trisphosphate 3-kinase activity|kinase activity|transferase activity|inositol hexakisphosphate 1-kinase activity|inositol hexakisphosphate 3-kinase activity|",9,0.7,2.23,9,-0.1,0.347,0.3,0.658,0.658,0.704,0,0,-0.7,2
ENSMUSG00000028926,CDK14,cyclin-dependent kinase 14,cytoplasmic cyclin-dependent protein kinase holoenzyme complex|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|membrane|,G2/M transition of mitotic cell cycle|protein phosphorylation|cell cycle|Wnt signaling pathway|phosphorylation|cell division|regulation of cell cycle|regulation of canonical Wnt signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cyclin binding|",10,-0.3,1.44,10,0.1,0.0649,-0.2,0.654,-0.654,0.705,0,0,-1.7,0.9
ENSMUSG00000073802,CDKN2B,"cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)",nucleus|cytoplasm|,regulation of cyclin-dependent protein serine/threonine kinase activity|G2/M transition of mitotic cell cycle|cell cycle|cell cycle arrest|mitotic cell cycle checkpoint|negative regulation of cell proliferation|phosphorylation|positive regulation of transforming growth factor beta receptor signaling pathway|cellular response to extracellular stimulus|cellular response to nutrient|negative regulation of phosphorylation|spleen development|negative regulation of epithelial cell proliferation|negative regulation of protein serine/threonine kinase activity|negative regulation of G1/S transition of mitotic cell cycle|,cyclin-dependent protein serine/threonine kinase inhibitor activity|kinase activity|transferase activity|protein kinase binding|,10,0.2,0.94,10,0.1,0.00685,0.2,0.652,0.652,0.705,0,0,-1.5,1.4
ENSMUSG00000062028,IRGC1,"immunity-related GTPase family, cinema 1",cellular_component|membrane|,biological_process|,"nucleotide binding|molecular_function|GTP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|",10,0.2,1.23,10,0,0,0.2,0.649,0.649,0.706,0,0,-1.1,1.6
ENSMUSG00000015599,TTBK1,tau tubulin kinase 1,cytoplasm|,protein phosphorylation|biological_process|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,0.185,10,-0.3,0.568,-0.2,0.641,-0.641,0.708,0,0,-1.4,1.3
ENSMUSG00000036334,IGSF10,"immunoglobulin superfamily, member 10",cellular_component|extracellular region|,ossification|tissue regeneration|,molecular_function|,9,-0.4,2.69,9,0,0,-0.3,0.639,-0.639,0.708,0,0,-2,0.6
ENSMUSG00000002205,VRK3,vaccinia related kinase 3,nucleus|nucleus|,protein phosphorylation|positive regulation of phosphoprotein phosphatase activity|negative regulation of ERK1 and ERK2 cascade|,"nucleotide binding|protein kinase activity|ATP binding|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|",10,-0.2,1.22,10,0,0,-0.2,0.628,-0.628,0.71,0,0,-1.7,1.1
ENSMUSG00000058454,DHCR7,7-dehydrocholesterol reductase,nuclear outer membrane|endoplasmic reticulum|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,blood vessel development|lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|post-embryonic development|sterol biosynthetic process|cell differentiation|lung development|multicellular organism growth|regulation of cell proliferation|regulation of cholesterol biosynthetic process|oxidation-reduction process|,"oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor|7-dehydrocholesterol reductase activity|7-dehydrocholesterol reductase activity|",10,-1.8,2.97,10,0.1,0.156,0.2,0.609,0.609,0.715,0,0,-2.9,1.2
ENSMUSG00000051022,HS3ST1,heparan sulfate (glucosamine) 3-O-sulfotransferase 1,Golgi apparatus|,None,sulfotransferase activity|[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity|transferase activity|,10,-0.1,0.247,10,-0.1,0.415,-0.1,0.606,-0.606,0.715,0,0,-1.3,1.6
ENSMUSG00000078650,G6PC,"glucose-6-phosphatase, catalytic",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,glycogen metabolic process|glycogen catabolic process|gluconeogenesis|triglyceride metabolic process|phosphate-containing compound metabolic process|steroid metabolic process|regulation of gene expression|glucose-6-phosphate transport|glucose-6-phosphate transport|dephosphorylation|dephosphorylation|multicellular organism growth|glucose homeostasis|glucose homeostasis|cholesterol homeostasis|urate metabolic process|phosphorylated carbohydrate dephosphorylation|glucose 6-phosphate metabolic process|glucose 6-phosphate metabolic process|lipid homeostasis|,"catalytic activity|glucose-6-phosphatase activity|glucose-6-phosphatase activity|glucose-6-phosphatase activity|phosphotransferase activity, alcohol group as acceptor|hydrolase activity|phosphate ion binding|",10,0.1,0.211,10,0.1,0.448,0.1,0.603,0.603,0.716,0,0,-1.1,1.6
ENSMUSG00000022705,DRD3,dopamine receptor D3,plasma membrane|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|endocytic vesicle|cell projection|apical part of cell|,"negative regulation of transcription from RNA polymerase II promoter|synaptic transmission, dopaminergic|response to amphetamine|regulation of blood volume by renin-angiotensin|regulation of blood volume by renin-angiotensin|G-protein coupled receptor internalization|cellular calcium ion homeostasis|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|adenylate cyclase-activating dopamine receptor signaling pathway|negative regulation of adenylate cyclase activity|adenylate cyclase-inhibiting dopamine receptor signaling pathway|dopamine receptor signaling pathway|synaptic transmission|locomotory behavior|locomotory behavior|positive regulation of cell proliferation|visual learning|regulation of dopamine secretion|regulation of lipid metabolic process|regulation of cAMP metabolic process|negative regulation of sodium:proton antiporter activity|positive regulation of cytokinesis|circadian regulation of gene expression|response to histamine|gastric emptying|positive regulation of renal sodium excretion|regulation of locomotion|regulation of multicellular organism growth|response to cocaine|response to drug|response to morphine|regulation of circadian sleep/wake cycle, sleep|response to ethanol|negative regulation of blood pressure|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|acid secretion|behavioral response to cocaine|behavioral response to cocaine|negative regulation of oligodendrocyte differentiation|arachidonic acid secretion|negative regulation of protein secretion|musculoskeletal movement, spinal reflex action|negative regulation of protein kinase B signaling|prepulse inhibition|negative regulation of dopamine receptor signaling pathway|positive regulation of dopamine receptor signaling pathway|regulation of locomotion involved in locomotory behavior|","dopamine neurotransmitter receptor activity, coupled via Gi/Go|dopamine neurotransmitter receptor activity, coupled via Gi/Go|signal transducer activity|G-protein coupled receptor activity|dopamine neurotransmitter receptor activity|protein binding|drug binding|protein domain specific binding|D1 dopamine receptor binding|dopamine binding|",10,0.4,0.138,10,-0.4,2.03,-0.3,0.6,-0.6,0.716,0,0,-1.5,1.3
ENSMUSG00000005677,NR1I3,"nuclear receptor subfamily 1, group I, member 3",nucleus|nucleus|cytoplasm|cytosol|cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|steroid hormone mediated signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|thyroid hormone receptor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0.4,1.96,0.3,0.578,0.578,0.721,0,0,-0.9,1.8
ENSMUSG00000004344,GPX5,glutathione peroxidase 5,extracellular region|,response to oxidative stress|oxidation-reduction process|,peroxidase activity|glutathione peroxidase activity|oxidoreductase activity|,9,0.1,0.397,9,0.2,0.402,0.2,0.569,0.569,0.723,0,0,-0.8,2
ENSMUSG00000026520,PYCR2,"pyrroline-5-carboxylate reductase family, member 2",cytoplasm|,proline biosynthetic process|cellular amino acid biosynthetic process|oxidation-reduction process|,pyrroline-5-carboxylate reductase activity|oxidoreductase activity|,10,0.3,1.09,10,0,0,0.1,0.566,0.566,0.724,0,0,-0.8,1.8
ENSMUSG00000018846,PANK3,pantothenate kinase 3,cytoplasm|,coenzyme A biosynthetic process|phosphorylation|,nucleotide binding|pantothenate kinase activity|ATP binding|kinase activity|transferase activity|,10,-0.1,0.581,10,-0.1,0.0333,-0.1,0.565,-0.565,0.724,0,0,-1.4,1.5
ENSMUSG00000029445,HPD,4-hydroxyphenylpyruvic acid dioxygenase,Golgi membrane|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|extracellular vesicular exosome|,L-phenylalanine catabolic process|tyrosine catabolic process|aromatic amino acid family metabolic process|oxidation-reduction process|,"4-hydroxyphenylpyruvate dioxygenase activity|quercetin 2,3-dioxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen|metal ion binding|dioxygenase activity|",10,0.2,0.83,10,0,0,0.1,0.564,0.564,0.724,0,0,-1.7,1.3
ENSMUSG00000023274,CD4,CD4 antigen,endoplasmic reticulum lumen|endoplasmic reticulum membrane|plasma membrane|plasma membrane|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|membrane raft|,cytokine production|cytokine production|immune system process|induction by virus of host cell-cell fusion|immune response|cell adhesion|cell surface receptor signaling pathway|T cell differentiation|T cell differentiation|maintenance of protein location in cell|T cell activation|T cell selection|T cell selection|protein palmitoleylation|positive regulation of protein kinase activity|positive regulation of peptidyl-tyrosine phosphorylation|defense response to Gram-negative bacterium|positive regulation of calcium-mediated signaling|regulation of T cell activation|positive regulation of T cell activation|,glycoprotein binding|protein binding|zinc ion binding|coreceptor activity|enzyme binding|protein kinase binding|protein homodimerization activity|,10,0.4,1.66,10,-0.6,0.753,0.1,0.556,0.556,0.726,0,0,-1.6,1.3
ENSMUSG00000023921,MUT,methylmalonyl-Coenzyme A mutase,mitochondrion|,metabolic process|post-embryonic development|homocysteine metabolic process|,catalytic activity|methylmalonyl-CoA mutase activity|isomerase activity|intramolecular transferase activity|cobalamin binding|metal ion binding|modified amino acid binding|,10,-0.3,2.1,10,0.2,0.274,-0.2,0.551,-0.551,0.727,0,0,-1.8,0.8
ENSMUSG00000040280,NDUFA4L2,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2",cellular_component|,biological_process|,molecular_function|,10,0.3,1.36,10,0,0,0.2,0.549,0.549,0.728,0,0,-2,1
ENSMUSG00000043991,PURA,purine rich element binding protein A,nucleus|nucleus|DNA replication factor A complex|cytoplasm|dendrite|neuronal cell body|,"DNA unwinding involved in DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|mitotic cell cycle checkpoint|nervous system development|cell proliferation|positive regulation of cell proliferation|negative regulation of translation|cell differentiation|negative regulation of transcription, DNA-templated|","translation repressor activity, nucleic acid binding|DNA binding|double-stranded DNA binding|double-stranded telomeric DNA binding|single-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|purine-rich negative regulatory element binding|poly(A) RNA binding|SMAD binding|",10,0.2,0.343,10,-0.4,1.29,-0.1,0.547,-0.547,0.728,0,0,-1.6,1.2
ENSMUSG00000035936,ALDH5A1,"aldhehyde dehydrogenase family 5, subfamily A1",mitochondrion|mitochondrion|,glucose metabolic process|acetate metabolic process|succinate metabolic process|succinate metabolic process|glutamate metabolic process|glutamine metabolic process|glycerophospholipid metabolic process|glucosylceramide metabolic process|galactosylceramide metabolic process|glutathione metabolic process|central nervous system development|metabolic process|gamma-aminobutyric acid metabolic process|gamma-aminobutyric acid catabolic process|gamma-aminobutyric acid catabolic process|post-embryonic development|respiratory electron transport chain|neurotransmitter catabolic process|short-chain fatty acid metabolic process|protein homotetramerization|oxidation-reduction process|,"succinate-semialdehyde dehydrogenase (NAD+) activity|succinate-semialdehyde dehydrogenase [NAD(P)+] activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|carboxylic acid binding|NAD binding|",10,0.2,0.572,10,-0.4,1.63,-0.3,0.545,-0.545,0.729,0,0,-1.7,0.9
ENSMUSG00000073422,H2-KE6,H2-K region expressed gene 6,mitochondrion|mitochondrial envelope|mitochondrial matrix|plasma membrane|membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|steroid biosynthetic process|estrogen biosynthetic process|metabolic process|androgen metabolic process|estrogen metabolic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|3-hydroxyacyl-CoA dehydrogenase activity|aldo-keto reductase (NADP) activity|estradiol 17-beta-dehydrogenase activity|estradiol 17-beta-dehydrogenase activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|testosterone dehydrogenase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,-0.3,0.798,10,0.1,0.0779,0.1,0.538,0.538,0.73,0,0,-1.4,1.7
ENSMUSG00000030849,FGFR2,fibroblast growth factor receptor 2,extracellular region|cell|nucleus|nucleus|cytoplasm|Golgi apparatus|plasma membrane|integral component of plasma membrane|cell cortex|cell surface|membrane|integral component of membrane|extracellular matrix|cytoplasmic vesicle|intracellular membrane-bounded organelle|excitatory synapse|,negative regulation of transcription from RNA polymerase II promoter|angiogenesis|ureteric bud development|in utero embryonic development|in utero embryonic development|epithelial to mesenchymal transition|positive regulation of mesenchymal cell proliferation|outflow tract septum morphogenesis|membranous septum morphogenesis|protein phosphorylation|apoptotic process|cell-cell signaling|axonogenesis|neuromuscular junction development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|regulation of smoothened signaling pathway|post-embryonic development|embryonic pattern specification|organ morphogenesis|regulation of cell fate commitment|positive regulation of phospholipase activity|phosphorylation|morphogenesis of embryonic epithelium|peptidyl-tyrosine phosphorylation|orbitofrontal cortex development|ventricular zone neuroblast division|pyramidal neuron development|gland morphogenesis|positive regulation of Wnt signaling pathway|bone mineralization|lung development|lung development|epithelial cell differentiation|midbrain development|otic vesicle formation|hair follicle morphogenesis|lacrimal gland development|multicellular organism growth|organ growth|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow|fibroblast growth factor receptor signaling pathway involved in hemopoiesis|fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow|fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development|regulation of multicellular organism growth|regulation of fibroblast growth factor receptor signaling pathway|regulation of cell proliferation|inner ear morphogenesis|odontogenesis|positive regulation of MAPK cascade|cell fate commitment|positive regulation of cell cycle|negative regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|lung alveolus development|lung alveolus development|synaptic vesicle transport|embryonic digestive tract morphogenesis|embryonic organ morphogenesis|digestive tract development|embryonic organ development|reproductive structure development|positive regulation of smooth muscle cell proliferation|embryonic cranial skeleton morphogenesis|epidermis morphogenesis|branching morphogenesis of a nerve|mesenchymal cell differentiation|epithelial cell proliferation|regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|regulation of smooth muscle cell differentiation|positive regulation of cell division|ventricular cardiac muscle tissue morphogenesis|positive regulation of cardiac muscle cell proliferation|limb bud formation|bone development|bone morphogenesis|coronal suture morphogenesis|epithelial tube branching involved in lung morphogenesis|branching involved in prostate gland morphogenesis|branching involved in salivary gland morphogenesis|bud elongation involved in lung branching|lung lobe morphogenesis|lung-associated mesenchyme development|lung-associated mesenchyme development|positive regulation of epithelial cell proliferation involved in lung morphogenesis|prostate gland morphogenesis|prostate epithelial cord elongation|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis|squamous basal epithelial stem cell differentiation involved in prostate gland acinus development|fibroblast growth factor receptor signaling pathway involved in mammary gland specification|lateral sprouting from an epithelium|mammary gland bud formation|epithelial cell proliferation involved in salivary gland morphogenesis|epithelial cell proliferation involved in salivary gland morphogenesis|branch elongation involved in salivary gland morphogenesis|branch elongation involved in salivary gland morphogenesis|branching involved in labyrinthine layer morphogenesis|regulation of branching involved in prostate gland morphogenesis|regulation of morphogenesis of a branching structure|mesenchymal cell differentiation involved in lung development|mesenchymal cell proliferation involved in lung development|vasculogenesis involved in coronary vascular morphogenesis|endodermal digestive tract morphogenesis|lens fiber cell development|lens fiber cell development|regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|fibroblast growth factor-activated receptor activity|protein binding|ATP binding|heparin binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|fibroblast growth factor binding|fibroblast growth factor binding|protein homodimerization activity|",9,0.4,1.69,9,-0.1,0.622,-0.1,0.533,-0.533,0.732,0,0,-1.1,1.7
ENSMUSG00000032594,IP6K1,inositol hexaphosphate kinase 1,nucleus|nucleus|nucleolus|cytoplasm|,inositol metabolic process|phosphorylation|inositol phosphate biosynthetic process|phosphatidylinositol phosphorylation|,"nucleotide binding|inositol hexakisphosphate 5-kinase activity|ATP binding|inositol-1,4,5-trisphosphate 3-kinase activity|kinase activity|transferase activity|inositol hexakisphosphate 1-kinase activity|inositol hexakisphosphate 3-kinase activity|",10,0.1,0.23,10,0.1,0.353,0.1,0.533,0.533,0.732,0,0,-1.3,1.6
ENSMUSG00000029663,GNGT1,"guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1",photoreceptor outer segment|photoreceptor inner segment|heterotrimeric G-protein complex|heterotrimeric G-protein complex|plasma membrane|membrane|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|phototransduction|protein localization|cardiac muscle cell apoptotic process|eye photoreceptor cell development|cellular response to hypoxia|,GTPase activity|signal transducer activity|,10,-0.4,1.76,10,0.2,0.78,-0.2,0.526,-0.526,0.733,0,0,-1.6,1
ENSMUSG00000028020,GLRB,"glycine receptor, beta subunit",cell|endoplasmic reticulum|plasma membrane|external side of plasma membrane|membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,"startle response|startle response|transport|ion transport|ion transport|chloride transport|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|synaptic transmission|acrosome reaction|nervous system development|nervous system development|visual perception|adult walking behavior|ion transmembrane transport|ion transmembrane transport|regulation of membrane potential|neuromuscular process|protein heterooligomerization|synaptic transmission, glycinergic|synaptic transmission, glycinergic|righting reflex|chloride transmembrane transport|chloride transmembrane transport|",extracellular ligand-gated ion channel activity|chloride channel activity|binding|protein binding|glycine binding|glycine binding|glycine binding|glycine binding|extracellular-glycine-gated ion channel activity|extracellular-glycine-gated ion channel activity|extracellular-glycine-gated chloride channel activity|extracellular-glycine-gated chloride channel activity|extracellular-glycine-gated chloride channel activity|,10,-0.4,2.36,10,0.3,1.68,-0.2,0.525,-0.525,0.733,0,0,-1.3,1.6
ENSMUSG00000035725,PRKX,"protein kinase, X-linked",nucleus|nucleus|cytoplasm|cytoplasm|,angiogenesis|angiogenesis|endothelial cell proliferation|endothelial cell proliferation|protein phosphorylation|cell adhesion|cell adhesion|multicellular organismal development|phosphorylation|peptidyl-serine phosphorylation|myeloid cell differentiation|cell differentiation|regulation of cell adhesion|regulation of cell migration|cell-substrate adhesion|endothelial cell migration|protein autophosphorylation|epithelial tube morphogenesis|kidney morphogenesis|regulation of epithelial cell differentiation involved in kidney development|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cAMP-dependent protein kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.477,10,0.1,0.0946,0.1,0.524,0.524,0.734,0,0,-1.3,1.5
ENSMUSG00000030399,CKM,"creatine kinase, muscle",cytoplasm|,phosphocreatine metabolic process|phosphorylation|phosphocreatine biosynthetic process|phosphocreatine biosynthetic process|,"nucleotide binding|catalytic activity|creatine kinase activity|creatine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.311,10,0.7,0.751,0.3,0.522,0.522,0.734,0,0,-1.2,1.8
ENSMUSG00000036905,C1QB,"complement component 1, q subcomponent, beta polypeptide",extracellular region|collagen trimer|complement component C1 complex|extracellular vesicular exosome|blood microparticle|,"immune system process|complement activation, classical pathway|innate immune response|inner ear development|",protein homodimerization activity|,10,0.2,0.601,10,0.1,0.134,0.1,0.518,0.518,0.735,0,0,-1.1,1.7
ENSMUSG00000033953,PPP3R1,"protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)",intracellular|cell|cytoplasm|plasma membrane|membrane|sarcolemma|,patterning of blood vessels|epithelial to mesenchymal transition|protein dephosphorylation|protein dephosphorylation|heart development|protein localization to nucleus|NFAT protein import into nucleus|lung epithelial cell differentiation|,phosphoprotein phosphatase activity|phosphoprotein phosphatase activity|calcium ion binding|protein binding|enzyme binding|protein domain specific binding|metal ion binding|,10,0.4,2.62,10,-0.7,0.84,0.3,0.518,0.518,0.735,0,0,-1.8,1.2
ENSMUSG00000052430,BMPR1B,"bone morphogenetic protein receptor, type 1B",membrane|integral component of membrane|,skeletal system development|cartilage condensation|ovarian cumulus expansion|eye development|chondrocyte differentiation|protein phosphorylation|protein phosphorylation|estrogen biosynthetic process|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|dorsal/ventral pattern formation|phosphorylation|cell differentiation|cell differentiation|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|retinal ganglion cell axon guidance|limb morphogenesis|ovulation cycle|camera-type eye development|positive regulation of cell differentiation|positive regulation of osteoblast differentiation|cartilage development|retina development in camera-type eye|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta receptor activity, type I|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SMAD binding|metal ion binding|",9,0.3,0.481,9,-0.1,0.185,0.2,0.517,0.517,0.735,0,0,-0.9,1.8
ENSMUSG00000046598,BDH1,"3-hydroxybutyrate dehydrogenase, type 1",nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|,metabolic process|oxidation-reduction process|,catalytic activity|3-hydroxybutyrate dehydrogenase activity|phospholipid binding|oxidoreductase activity|,9,-0.3,1.46,9,0,0,-0.2,0.516,-0.516,0.735,0,0,-1.7,1.2
ENSMUSG00000009828,ICK,intestinal cell kinase,cytoplasm|,protein phosphorylation|protein phosphorylation|signal transduction|multicellular organismal development|phosphorylation|intracellular signal transduction|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.1,0.0659,10,-0.2,0.507,-0.1,0.511,-0.511,0.737,0,0,-1.6,1.3
ENSMUSG00000030330,ING4,"inhibitor of growth family, member 4",histone acetyltransferase complex|nucleus|,"DNA replication|protein acetylation|apoptotic process|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cell cycle|cell cycle arrest|negative regulation of cell proliferation|chromatin modification|histone acetylation|positive regulation of apoptotic process|histone H3 acetylation|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K12 acetylation|negative regulation of transcription, DNA-templated|negative regulation of growth|",transcription coactivator activity|zinc ion binding|methylated histone binding|metal ion binding|,10,0.1,0.0387,10,0.3,0.644,0.2,0.51,0.51,0.737,0,0,-1.1,1.8
ENSMUSG00000074923,PAK6,p21 protein (Cdc42/Rac)-activated kinase 6,nucleus|cytoplasm|,protein phosphorylation|learning|memory|locomotory behavior|phosphorylation|signal transduction by phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.5,0.764,10,0.1,0.14,-0.1,0.504,-0.504,0.738,0,0,-1.8,0.9
ENSMUSG00000027199,GATM,glycine amidinotransferase (L-arginine:glycine amidinotransferase),cytoplasm|mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|membrane|extracellular vesicular exosome|,creatine biosynthetic process|response to nutrient|response to organic substance|response to peptide hormone|response to mercury ion|,"amidinotransferase activity|glycine amidinotransferase activity|transferase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines|",10,-0.1,0.11,10,-0.1,0.439,-0.1,0.503,-0.503,0.738,0,0,-1.9,0.9
ENSMUSG00000045775,SLC16A5,"solute carrier family 16 (monocarboxylic acid transporters), member 5",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,0.1,0.234,10,0.1,0.308,0.1,0.496,0.496,0.74,0,0,-1.2,1.6
ENSMUSG00000025486,SIRT3,sirtuin 3,cytoplasm|mitochondrion|mitochondrion|membrane|,protein deacetylation|protein deacetylation|aerobic respiration|peptidyl-lysine deacetylation|histone H3 deacetylation|,"histone deacetylase activity|protein binding|zinc ion binding|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|enzyme binding|NAD-dependent histone deacetylase activity (H3-K14 specific)|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|metal ion binding|N-acetylgalactosamine-6-phosphate deacetylase activity|NAD binding|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|NAD+ binding|",10,0.2,0.834,10,0,0,0.1,0.491,0.491,0.741,0,0,-0.8,1.9
ENSMUSG00000031683,LSM6,"LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)",nucleus|spliceosomal complex|cytoplasm|ribonucleoprotein complex|extracellular vesicular exosome|,rRNA processing|mRNA processing|mRNA catabolic process|tRNA processing|RNA splicing|,RNA binding|poly(A) RNA binding|protein heterodimerization activity|,8,-0.1,0.244,8,0.3,1.15,0.2,0.491,0.491,0.741,0,0,-1.5,1.5
ENSMUSG00000053137,MAPK11,mitogen-activated protein kinase 11,intracellular|nucleus|cytoplasm|,"MAPK cascade|MAPK cascade|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|response to stress|phosphorylation|intracellular signal transduction|intracellular signal transduction|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|MAP kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.5,2.25,10,0,0,0.2,0.48,0.48,0.744,0,0,-0.5,1.9
ENSMUSG00000021609,SLC6A3,"solute carrier family 6 (neurotransmitter transporter, dopamine), member 3",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|axon|neuron projection|neuronal cell body|,transport|neurotransmitter transport|lactation|sensory perception of smell|locomotory behavior|locomotory behavior|monoamine transport|dopamine transport|dopamine transport|adenohypophysis development|ion transmembrane transport|sodium ion transmembrane transport|positive regulation of multicellular organism growth|regulation of dopamine metabolic process|response to cocaine|dopamine biosynthetic process|dopamine catabolic process|response to ethanol|response to cAMP|prepulse inhibition|,protease binding|receptor binding|neurotransmitter:sodium symporter activity|dopamine transmembrane transporter activity|dopamine transmembrane transporter activity|dopamine:sodium symporter activity|protein binding|drug binding|monoamine transmembrane transporter activity|symporter activity|protein complex binding|dopamine binding|protein N-terminus binding|,10,0.1,0.259,10,0.2,0.277,0.1,0.469,0.469,0.747,0,0,-1.1,1.6
ENSMUSG00000030054,GP9,glycoprotein 9 (platelet),membrane|integral component of membrane|,cell adhesion|blood coagulation|hemostasis|biological_process|,molecular_function|,10,-0.2,0.41,10,-0.1,0.139,-0.1,0.453,-0.453,0.751,0,0,-1.7,1
ENSMUSG00000020516,RPS6KB1,"ribosomal protein S6 kinase, polypeptide 1",intracellular|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|cell surface|membrane|cell junction|neuron projection|synapse|perinuclear region of cytoplasm|,G1/S transition of mitotic cell cycle|regulation of translation|protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|cell cycle|signal transduction|germ cell development|positive regulation of smooth muscle cell migration|phosphorylation|TOR signaling|response to insulin|response to tumor necrosis factor|negative regulation of apoptotic process|negative regulation of apoptotic process|protein kinase B signaling|positive regulation of translation|positive regulation of mitotic cell cycle|positive regulation of translational initiation|regulation of glucose import|negative regulation of insulin receptor signaling pathway|positive regulation of skeletal muscle tissue growth|positive regulation of smooth muscle cell proliferation|cellular response to growth factor stimulus|negative regulation of extrinsic apoptotic signaling pathway|,"nucleotide binding|protein kinase activity|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|ribosomal protein S6 kinase activity|protein serine/threonine/tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|peptide binding|",9,-0.4,1.66,9,0.4,1.74,-0.1,0.451,-0.451,0.751,0,0,-1.4,1.4
ENSMUSG00000035112,WNK4,WNK lysine deficient protein kinase 4,cytoplasm|tight junction|cell junction|,protein phosphorylation|ion transport|chloride transport|protein localization|phosphorylation|cellular chloride ion homeostasis|regulation of cellular process|ion homeostasis|renal sodium ion absorption|distal tubule morphogenesis|negative regulation of pancreatic juice secretion|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|chloride channel inhibitor activity|",10,0.2,1.15,10,0,0,0.1,0.444,0.444,0.753,0,0,-1.3,1.6
ENSMUSG00000070880,GAD1,glutamate decarboxylase 1,intracellular|cytoplasm|mitochondrion|cell cortex|axon|axon terminus|neuron projection terminus|synapse|presynaptic active zone|,gamma-aminobutyric acid biosynthetic process|carboxylic acid metabolic process|neurotransmitter biosynthetic process|,catalytic activity|glutamate decarboxylase activity|glutamate binding|lyase activity|carboxy-lyase activity|pyridoxal phosphate binding|protein heterodimerization activity|protein N-terminus binding|,10,-0.1,0.281,9,-0.1,0.205,-0.1,0.444,-0.444,0.753,0,0,-1.6,1.3
ENSMUSG00000033717,ADRA2A,"adrenergic receptor, alpha 2a",cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|synapse|,positive regulation of cytokine production|acute inflammatory response|DNA replication|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|female pregnancy|positive regulation of cell migration|negative regulation of cAMP biosynthetic process|activation of protein kinase activity|activation of protein kinase B activity|cellular response to hormone stimulus|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway|glucose homeostasis|fear response|positive regulation of MAP kinase activity|positive regulation of epidermal growth factor-activated receptor activity|positive regulation of vasodilation|negative regulation of calcium ion-dependent exocytosis|negative regulation of insulin secretion|thermoception|negative regulation of lipid catabolic process|positive regulation of membrane protein ectodomain proteolysis|negative regulation of insulin secretion involved in cellular response to glucose stimulus|negative regulation of uterine smooth muscle contraction|adrenergic receptor signaling pathway|adenylate cyclase-inhibiting adrenergic receptor signaling pathway|phospholipase C-activating adrenergic receptor signaling pathway|activation of MAPK activity by adrenergic receptor signaling pathway|positive regulation of wound healing|,signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|alpha2-adrenergic receptor activity|alpha2-adrenergic receptor activity|protein kinase binding|alpha-2C adrenergic receptor binding|thioesterase binding|heterotrimeric G-protein binding|protein homodimerization activity|protein heterodimerization activity|epinephrine binding|norepinephrine binding|,10,-0.1,0.142,10,-0.2,0.384,-0.1,0.441,-0.441,0.754,0,0,-1.4,1.5
ENSMUSG00000005952,TRPV1,"transient receptor potential cation channel, subfamily V, member 1",cytosol|plasma membrane|external side of plasma membrane|membrane|membrane|integral component of membrane|cell junction|dendrite|intrinsic component of plasma membrane|cell projection|neuron projection|neuronal cell body|synapse|postsynaptic membrane|,temperature homeostasis|fever generation|microglial cell activation|diet induced thermogenesis|peptide secretion|lipid metabolic process|transport|ion transport|cation transport|calcium ion transport|calcium ion transport|calcium ion transport|signal transduction|positive regulation of cytosolic calcium ion concentration|response to pH|response to pH|response to heat|response to heat|response to organonitrogen compound|glutamate secretion|urinary bladder smooth muscle contraction|sensory perception of pain|ion transmembrane transport|catagen|positive regulation of apoptotic process|positive regulation of nitric oxide biosynthetic process|response to pain|response to pain|behavioral response to pain|sensory perception of mechanical stimulus|thermoception|detection of chemical stimulus involved in sensory perception of pain|detection of chemical stimulus involved in sensory perception of pain|transmembrane transport|smooth muscle contraction involved in micturition|positive regulation of gastric acid secretion|calcium ion transmembrane transport|calcium ion transmembrane transport|cellular response to alkaloid|cellular response to ATP|cellular response to cytokine stimulus|negative regulation of establishment of blood-brain barrier|,nucleotide binding|transmembrane signaling receptor activity|ion channel activity|excitatory extracellular ligand-gated ion channel activity|cation channel activity|cation channel activity|calcium channel activity|calmodulin binding|ATP binding|cation transmembrane transporter activity|ligand-gated ion channel activity|calcium-release channel activity|chloride channel regulator activity|identical protein binding|phosphoprotein binding|,9,-0.1,0.0908,9,-0.2,0.484,-0.1,0.438,-0.438,0.754,0,0,-1.3,1.7
ENSMUSG00000026674,DDR2,"discoidin domain receptor family, member 2",plasma membrane|membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,ossification|endochondral bone growth|protein phosphorylation|cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of cell proliferation|positive regulation of fibroblast migration|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|collagen fibril organization|regulation of bone mineralization|biomineral tissue development|chondrocyte proliferation|collagen-activated tyrosine kinase receptor signaling pathway|collagen-activated tyrosine kinase receptor signaling pathway|positive regulation of osteoblast differentiation|positive regulation of protein kinase activity|protein autophosphorylation|positive regulation of fibroblast proliferation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of extracellular matrix disassembly|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|collagen binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein tyrosine kinase collagen receptor activity|protein tyrosine kinase collagen receptor activity|",10,-0.1,0.0742,9,-0.1,0.396,-0.1,0.431,-0.431,0.756,0,0,-1.9,0.9
ENSMUSG00000002409,DYRK1B,dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b,nucleus|,"protein phosphorylation|myoblast fusion|phosphorylation|positive regulation of transcription, DNA-templated|","nucleotide binding|transcription coactivator activity|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.7,0.976,10,-0.8,2.07,0.2,0.431,0.431,0.756,0,0,-2,1.3
ENSMUSG00000037593,BC030499,cDNA sequence BC030499,cellular_component|,protein phosphorylation|phosphorylation|,"nucleotide binding|molecular_function|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.0591,10,-0.1,0.409,-0.1,0.429,-0.429,0.756,0,0,-1.8,0.9
ENSMUSG00000019579,D17WSU104E,"DNA segment, Chr 17, Wayne State University 104, expressed",extracellular region|extracellular vesicular exosome|,None,None,10,-0.3,1.04,10,-0.1,0.0415,-0.2,0.426,-0.426,0.757,0,0,-1.8,1
ENSMUSG00000096062,PIK3C2G,"phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide",nuclear envelope|Golgi apparatus|plasma membrane|plasma membrane|phosphatidylinositol 3-kinase complex|membrane|,chemotaxis|phosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|,"nucleotide binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|1-phosphatidylinositol-4-phosphate 3-kinase activity|1-phosphatidylinositol-4-phosphate 3-kinase activity|phosphatidylinositol binding|",10,-0.2,1.12,10,0.1,0.32,-0.1,0.423,-0.423,0.758,0,0,-1.8,0.9
ENSMUSG00000028036,PTGFR,prostaglandin F receptor,cytoplasm|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|response to lipopolysaccharide|calcium-mediated signaling using intracellular calcium source|negative regulation of apoptotic process|,signal transducer activity|G-protein coupled receptor activity|prostaglandin receptor activity|prostaglandin F receptor activity|,10,-0.1,0.23,10,0.7,1.63,0.4,0.423,0.423,0.758,0,0,-0.6,2
ENSMUSG00000028708,MKNK1,MAP kinase-interacting serine/threonine kinase 1,intracellular|,regulation of translation|regulation of translational initiation|protein phosphorylation|protein phosphorylation|response to salt stress|phosphorylation|peptidyl-serine phosphorylation|intracellular signal transduction|intracellular signal transduction|extrinsic apoptotic signaling pathway in absence of ligand|extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0.1,0.0969,9,0.1,0.363,0.1,0.421,0.421,0.758,0,0,-1.4,1.5
ENSMUSG00000034656,CACNA1A,"calcium channel, voltage-dependent, P/Q type, alpha 1A subunit",cell|nucleus|cytoplasm|plasma membrane|voltage-gated calcium channel complex|voltage-gated calcium channel complex|membrane|integral component of membrane|dendrite|cell projection|neuronal cell body|perikaryon|protein complex|,"sulfur amino acid metabolic process|glucose metabolic process|transport|ion transport|calcium ion transport|calcium ion transport|positive regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration|gamma-aminobutyric acid signaling pathway|synaptic transmission|synaptic transmission|neuron-neuron synaptic transmission|neuromuscular synaptic transmission|synapse assembly|adult walking behavior|adult walking behavior|cell death|gamma-aminobutyric acid secretion|regulation of acetylcholine secretion, neurotransmission|cell growth|calcium ion-dependent exocytosis|regulation of calcium ion-dependent exocytosis|transmission of nerve impulse|sensory perception of pain|spinal cord motor neuron differentiation|cerebellum maturation|cerebellar molecular layer development|cerebellar Purkinje cell layer development|cerebellar Purkinje cell differentiation|vestibular nucleus development|central nervous system neuron differentiation|cellular chloride ion homeostasis|negative regulation of hormone biosynthetic process|regulation of ion transmembrane transport|synaptic transmission, glutamatergic|neurotransmitter metabolic process|regulation of membrane potential|thyroid hormone metabolic process|hormone metabolic process|receptor clustering|negative regulation of neuron apoptotic process|response to pain|behavioral response to pain|calcium ion-dependent exocytosis of neurotransmitter|dendrite morphogenesis|regulation of axonogenesis|neurological system process|musculoskeletal movement, spinal reflex action|neuromuscular process controlling balance|neuromuscular process|neuromuscular process|membrane depolarization|transmembrane transport|rhythmic synaptic transmission|calcium ion import|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|",DNA binding|ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|calmodulin binding|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|syntaxin binding|metal ion binding|,10,-0.4,1.06,10,0.1,0.0448,-0.1,0.42,-0.42,0.759,0,0,-1.7,0.9
ENSMUSG00000026824,KCNJ3,"potassium inwardly-rectifying channel, subfamily J, member 3",external side of plasma membrane|cell surface|membrane|integral component of membrane|T-tubule|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|G-protein activated inward rectifier potassium channel activity|,10,-0.3,0.412,10,-0.1,0.215,-0.2,0.42,-0.42,0.759,0,0,-1.9,0.8
ENSMUSG00000001027,SCN4A,"sodium channel, voltage-gated, type IV, alpha",voltage-gated sodium channel complex|plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|potassium ion transport|sodium ion transport|sodium ion transport|choline transport|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|transmembrane transport|potassium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|potassium channel activity|sodium channel activity|,10,0.1,0.254,10,-0.8,3.16,-0.1,0.419,-0.419,0.759,0,0,-2,0.9
ENSMUSG00000031849,COMP,cartilage oligomeric matrix protein,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,growth plate cartilage development|growth plate cartilage development|apoptotic process|cell adhesion|extracellular matrix organization|negative regulation of apoptotic process|limb development|,fibronectin binding|protease binding|protease binding|extracellular matrix structural constituent|vitamin D binding|calcium ion binding|protein binding|collagen binding|heparin binding|heparan sulfate proteoglycan binding|,10,-0.2,0.317,10,-0.1,0.153,-0.1,0.418,-0.418,0.759,0,0,-1.8,0.9
ENSMUSG00000022221,RIPK3,receptor-interacting serine-threonine kinase 3,intracellular|cytoplasm|mitochondrion|cytosol|plasma membrane|membrane|ripoptosome|,"regulation of T cell mediated cytotoxicity|regulation of adaptive immune response|protein phosphorylation|I-kappaB kinase/NF-kappaB signaling|positive regulation of phosphatase activity|programmed cell death|viral process|phosphorylation|signal transduction by phosphorylation|activation of protein kinase activity|regulation of interferon-gamma production|T cell differentiation in thymus|NIK/NF-kappaB signaling|T cell homeostasis|regulation of activated T cell proliferation|protein autophosphorylation|lymph node development|spleen development|thymus development|positive regulation of NF-kappaB transcription factor activity|protein homooligomerization|protein heterooligomerization|positive regulation of transferase activity|positive regulation of ligase activity|positive regulation of oxidoreductase activity|positive regulation of necroptotic process|positive regulation of necroptotic process|regulation of activation-induced cell death of T cells|necroptotic process|necroptotic process|necroptotic process|positive regulation of protein deacetylation|amyloid fibril formation|regulation of reactive oxygen species metabolic process|positive regulation of reactive oxygen species metabolic process|regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation|positive regulation of intrinsic apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein complex binding|identical protein binding|",10,0,0,10,0.8,2.94,0.1,0.416,0.416,0.76,0,0,-0.8,2
ENSMUSG00000000889,DBH,dopamine beta hydroxylase,cytoplasm|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|axon|dendrite|cytoplasmic vesicle|neuronal cell body|terminal bouton|varicosity|apical part of cell|synapse|,cytokine production|blood vessel remodeling|response to amphetamine|leukocyte mediated immunity|memory|locomotory behavior|associative learning|visual learning|regulation of cell proliferation|homoiothermy|dopamine catabolic process|norepinephrine biosynthetic process|norepinephrine biosynthetic process|catecholamine biosynthetic process|glucose homeostasis|glucose homeostasis|fear response|maternal behavior|positive regulation of vasoconstriction|octopamine metabolic process|behavioral response to ethanol|response to pain|leukocyte migration|oxidation-reduction process|regulation of extrinsic apoptotic signaling pathway|,"catalytic activity|monooxygenase activity|dopamine beta-monooxygenase activity|copper ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen|L-ascorbic acid binding|metal ion binding|",10,-0.3,1.2,10,0,0,-0.2,0.414,-0.414,0.76,0,0,-1.7,1
ENSMUSG00000063683,GLYAT,glycine-N-acyltransferase,mitochondrion|extracellular vesicular exosome|,biological_process|response to toxic substance|,"transferase activity|transferase activity, transferring acyl groups|glycine N-acyltransferase activity|glycine N-benzoyltransferase activity|",10,0.2,0.751,10,-0.1,0.33,0.1,0.412,0.412,0.761,0,0,-1.6,1.2
ENSMUSG00000036938,TRY5,trypsin 5,extracellular space|extracellular vesicular exosome|,proteolysis|,serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.1,0.89,-0.1,0.404,-0.404,0.763,0,0,-1.5,1.3
ENSMUSG00000026773,PFKFB3,"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3",nucleus|,"fructose 2,6-bisphosphate metabolic process|phosphorylation|","6-phosphofructo-2-kinase activity|fructose-2,6-bisphosphate 2-phosphatase activity|kinase activity|transferase activity|hydrolase activity|",10,0.1,0.18,10,0.1,0.26,0.1,0.402,0.402,0.764,0,0,-1,1.7
ENSMUSG00000049112,OXTR,oxytocin receptor,intracellular|plasma membrane|microvillus|cell-cell adherens junction|membrane|integral component of membrane|apical plasma membrane|,"suckling behavior|response to amphetamine|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|memory|positive regulation of norepinephrine secretion|sleep|positive regulation of synaptic transmission, GABAergic|response to anoxia|social behavior|maternal behavior|sperm ejaculation|eating behavior|regulation of digestive system process|positive regulation of blood pressure|response to steroid hormone|positive regulation of synapse assembly|positive regulation of synaptic transmission, glutamatergic|positive regulation of penile erection|negative regulation of gastric acid secretion|ERK1 and ERK2 cascade|positive regulation of uterine smooth muscle contraction|",signal transducer activity|G-protein coupled receptor activity|oxytocin receptor activity|vasopressin receptor activity|peptide hormone binding|,9,0.1,0.23,9,0.1,0.208,0.1,0.399,0.399,0.764,0,0,-1.4,1.6
ENSMUSG00000051716,APON,apolipoprotein N,extracellular space|cytoplasm|,biological_process|,molecular_function|,10,-0.4,1.21,10,0,0,-0.2,0.398,-0.398,0.765,0,0,-1.8,0.8
ENSMUSG00000025002,CYP2C55,"cytochrome P450, family 2, subfamily c, polypeptide 55",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,arachidonic acid metabolic process|linoleic acid metabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|arachidonic acid epoxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|aromatase activity|linoleic acid epoxygenase activity|",9,-0.2,0.989,9,0.4,1.84,0.2,0.394,0.394,0.766,0,0,-1.4,1.5
ENSMUSG00000001155,FTCD,formiminotransferase cyclodeaminase,cytoplasm|Golgi apparatus|Golgi apparatus|cytoskeleton|extracellular vesicular exosome|,histidine metabolic process|histidine catabolic process|cytoskeleton organization|metabolic process|cellular metabolic process|,catalytic activity|folic acid binding|transferase activity|lyase activity|glutamate formimidoyltransferase activity|formimidoyltetrahydrofolate cyclodeaminase activity|formimidoyltetrahydrofolate cyclodeaminase activity|,9,-0.2,0.709,9,0.2,0.119,-0.1,0.39,-0.39,0.767,0,0,-1.4,1.6
ENSMUSG00000036646,MAN1B1,"mannosidase, alpha, class 1B, member 1",endoplasmic reticulum|membrane|integral component of membrane|,metabolic process|ER-associated ubiquitin-dependent protein catabolic process|ER-associated ubiquitin-dependent protein catabolic process|,"mannosyl-oligosaccharide 1,2-alpha-mannosidase activity|mannosyl-oligosaccharide 1,2-alpha-mannosidase activity|calcium ion binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,-0.3,1.11,9,0.7,1.41,-0.2,0.387,-0.387,0.767,0,0,-1.4,1.7
ENSMUSG00000026213,STK11IP,serine/threonine kinase 11 interacting protein,cytoplasm|lysosomal membrane|intracellular membrane-bounded organelle|,protein localization|,protein kinase binding|,9,-0.5,1.71,9,0,0,-0.1,0.38,-0.38,0.769,0,0,-1.9,0.9
ENSMUSG00000061232,H2-K1,"histocompatibility 2, K1, K region",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,"positive regulation of T cell mediated cytotoxicity|immune system process|antigen processing and presentation of peptide antigen via MHC class I|antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent|immune response|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class I|defense response to bacterium|inner ear development|",receptor binding|protein binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,-0.2,0.55,10,0,0,-0.1,0.38,-0.38,0.769,0,0,-1.4,1.5
ENSMUSG00000041202,PLA2G2D,"phospholipase A2, group IID",extracellular region|cytoplasm|,lipid metabolic process|phospholipid metabolic process|lipid catabolic process|,phospholipase A2 activity|calcium ion binding|hydrolase activity|metal ion binding|,10,-0.5,0.582,10,0.3,0.769,0.2,0.373,0.373,0.771,0,0,-1.3,1.6
ENSMUSG00000026836,ACVR1,"activin A receptor, type 1",integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|apical part of cell|activin receptor complex|,"G1/S transition of mitotic cell cycle|patterning of blood vessels|urogenital system development|in utero embryonic development|gastrulation with mouth forming second|mesoderm formation|neural crest cell migration|embryonic heart tube morphogenesis|mitral valve morphogenesis|atrial septum primum morphogenesis|protein phosphorylation|protein phosphorylation|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|germ cell development|determination of left/right symmetry|gastrulation|mesoderm development|heart development|embryo development|negative regulation of signal transduction|positive regulation of pathway-restricted SMAD protein phosphorylation|phosphorylation|peptidyl-threonine phosphorylation|signal transduction by phosphorylation|regulation of ossification|positive regulation of bone mineralization|BMP signaling pathway|activin receptor signaling pathway|activin receptor signaling pathway|negative regulation of activin receptor signaling pathway|intracellular signal transduction|positive regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|smooth muscle cell differentiation|pharyngeal system development|pathway-restricted SMAD protein phosphorylation|cardiac muscle cell fate commitment|endocardial cushion cell fate commitment|positive regulation of determination of dorsal identity|negative regulation of extrinsic apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|transforming growth factor beta receptor activity, type I|ATP binding|kinase activity|activin receptor activity, type I|activin receptor activity, type I|activin receptor activity, type I|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|protein homodimerization activity|SMAD binding|metal ion binding|activin binding|activin binding|transforming growth factor beta binding|transforming growth factor beta binding|",9,-0.1,0.272,9,0.7,2.38,0.3,0.37,0.37,0.772,0,0,-0.7,2
ENSMUSG00000039954,STK32A,serine/threonine kinase 32A,cellular_component|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.2,0.241,10,0.3,0.81,0.1,0.368,0.368,0.772,0,0,-1.5,1.3
ENSMUSG00000038372,GMDS,"GDP-mannose 4, 6-dehydratase",cellular_component|,GDP-mannose metabolic process|,"catalytic activity|GDP-mannose 4,6-dehydratase activity|lyase activity|coenzyme binding|",10,0,0,10,0.2,1.43,0.1,0.368,0.368,0.772,0,0,-1.1,1.7
ENSMUSG00000032462,PIK3CB,"phosphatidylinositol 3-kinase, catalytic, beta polypeptide",nucleus|cytoplasm|plasma membrane|phosphatidylinositol 3-kinase complex|phosphatidylinositol 3-kinase complex|brush border membrane|,regulation of cell-matrix adhesion|cellular calcium ion homeostasis|endocytosis|autophagy|cell adhesion|homophilic cell adhesion|phosphorylation|platelet activation|phosphatidylinositol-3-phosphate biosynthetic process|phosphatidylinositol-3-phosphate biosynthetic process|embryonic cleavage|phosphatidylinositol phosphorylation|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|,"nucleotide binding|protein binding|ATP binding|kinase activity|1-phosphatidylinositol-3-kinase activity|1-phosphatidylinositol-3-kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|1-phosphatidylinositol-4-phosphate 3-kinase activity|insulin receptor substrate binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|",10,0.2,1.47,10,0,0,0.1,0.364,0.364,0.774,0,0,-1.1,1.7
ENSMUSG00000037940,INPP4B,"inositol polyphosphate-4-phosphatase, type II",cytoplasm|Golgi apparatus|,cellular calcium ion homeostasis|dephosphorylation|phosphatidylinositol-3-phosphate biosynthetic process|negative regulation of osteoclast differentiation|negative regulation of osteoclast differentiation|regulation of nucleocytoplasmic transport|regulation of bone remodeling|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|regulation of protein kinase B signaling|,"lipid binding|phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity|hydrolase activity|phosphatidylinositol bisphosphate phosphatase activity|phosphatidylinositol trisphosphate phosphatase activity|phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity|",9,0,0,9,-0.2,0.832,-0.1,0.362,-0.362,0.774,0,0,-1.8,1
ENSMUSG00000025665,RPS6KA6,ribosomal protein S6 kinase polypeptide 6,intracellular|nucleus|cytoplasm|,"protein phosphorylation|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|phosphorylation|intracellular signal transduction|negative regulation of embryonic development|negative regulation of ERK1 and ERK2 cascade|negative regulation of mesoderm development|","nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.1,0.513,10,-0.1,0.663,0.1,0.349,0.349,0.778,0,0,-1.4,1.3
ENSMUSG00000054446,CPA1,"carboxypeptidase A1, pancreatic",extracellular region|extracellular space|,proteolysis|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|exopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.3,1.8,10,-1.1,1.9,-0.3,0.348,-0.348,0.778,0,0,-2,0.3
ENSMUSG00000028755,CDA,cytidine deaminase,cytosol|,cytidine deamination|negative regulation of cell growth|negative regulation of nucleotide metabolic process|protein homotetramerization|,nucleoside binding|catalytic activity|cytidine deaminase activity|zinc ion binding|hydrolase activity|identical protein binding|protein homodimerization activity|metal ion binding|,10,0.3,0.734,10,-0.1,0.199,0.2,0.344,0.344,0.779,0,0,-1.1,1.6
ENSMUSG00000045471,HCRT,hypocretin,cytoplasm|endoplasmic reticulum|cell junction|secretory granule|cytoplasmic vesicle|synapse|perinuclear region of cytoplasm|,temperature homeostasis|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|protein kinase C-activating G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|feeding behavior|negative regulation of DNA replication|eating behavior|negative regulation of potassium ion transport|regulation of neurotransmitter secretion|positive regulation of calcium ion transport|negative regulation of transmission of nerve impulse|positive regulation of transmission of nerve impulse|regulation of excitatory postsynaptic membrane potential|,neuropeptide hormone activity|type 1 hypocretin receptor binding|type 2 hypocretin receptor binding|,10,0.3,1.68,10,-0.6,0.166,0.2,0.333,0.333,0.782,0,0,-1.7,1.2
ENSMUSG00000031924,CYB5B,cytochrome b5 type B,mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,transport|positive regulation of catalytic activity|oxidation-reduction process|,enzyme activator activity|heme binding|metal ion binding|,9,-0.1,0.0594,9,-0.1,0.304,-0.1,0.332,-0.332,0.782,0,0,-1.7,1.4
ENSMUSG00000022092,PPP3CC,"protein phosphatase 3, catalytic subunit, gamma isoform",extracellular vesicular exosome|,None,phosphoprotein phosphatase activity|calmodulin binding|hydrolase activity|metal ion binding|,10,-0.1,0.236,10,0.3,0.745,0.1,0.328,0.328,0.783,0,0,-1.4,1.4
ENSMUSG00000038349,PLCL1,phospholipase C-like 1,cytoplasm|plasma membrane|,"lipid metabolic process|signal transduction|gamma-aminobutyric acid signaling pathway|regulation of synaptic transmission, GABAergic|regulation of synaptic transmission, GABAergic|regulation of peptidyl-serine phosphorylation|intracellular signal transduction|positive regulation of receptor binding|","phosphatidylinositol phospholipase C activity|signal transducer activity|calcium ion binding|phosphoric diester hydrolase activity|GABA receptor binding|GABA receptor binding|inositol 1,4,5 trisphosphate binding|",10,0.3,0.62,10,0,0,0.1,0.328,0.328,0.783,0,0,-1.1,1.7
ENSMUSG00000022206,NPR3,natriuretic peptide receptor 3,intracellular|membrane|integral component of membrane|extracellular vesicular exosome|,skeletal system development|skeletal system development|osteoclast proliferation|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|phospholipase C-activating G-protein coupled receptor signaling pathway|regulation of blood pressure|regulation of blood pressure|pancreatic juice secretion|regulation of osteoblast proliferation|positive regulation of urine volume|phosphatidylinositol-mediated signaling|negative regulation of smooth muscle cell proliferation|positive regulation of nitric-oxide synthase activity|,G-protein coupled peptide receptor activity|natriuretic peptide receptor activity|peptide hormone binding|hormone binding|protein homodimerization activity|,8,-0.3,1.64,8,0,0,-0.2,0.323,-0.323,0.785,0,0,-2,0.8
ENSMUSG00000014609,CHRNE,"cholinergic receptor, nicotinic, epsilon polypeptide",plasma membrane|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,skeletal muscle contraction|transport|ion transport|cation transport|ion transmembrane transport|regulation of membrane potential|,acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|,10,0,0,10,-0.1,0.671,-0.1,0.315,-0.315,0.787,0,0,-1.6,1.3
ENSMUSG00000061462,OBSCN,"obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF",striated muscle myosin thick filament|sarcomere|Z disc|M band|M band|,protein phosphorylation|multicellular organismal development|phosphorylation|cell differentiation|regulation of Rho protein signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|Rho guanyl-nucleotide exchange factor activity|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|ankyrin binding|titin binding|",10,0,0,10,-0.2,0.772,-0.1,0.311,-0.311,0.788,0,0,-1.6,1.3
ENSMUSG00000020115,TBK1,TANK-binding kinase 1,cytoplasm|,activation of innate immune response|immune system process|protein phosphorylation|negative regulation of gene expression|phosphorylation|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|dendritic cell proliferation|innate immune response|positive regulation of interferon-beta biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|defense response to Gram-positive bacterium|defense response to virus|,"nucleotide binding|nucleic acid binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphoprotein binding|",10,0.1,0.165,10,0.6,0.356,0.1,0.308,0.308,0.789,0,0,-1.1,1.8
ENSMUSG00000062345,SERPINB2,"serine (or cysteine) peptidase inhibitor, clade B, member 2",extracellular region|extracellular space|cytoplasm|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|wound healing|negative regulation of apoptotic process|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.3,1.15,10,0.1,0.0755,-0.1,0.304,-0.304,0.79,0,0,-2,0.7
ENSMUSG00000026387,SCTR,secretin receptor,cytoplasmic microtubule|plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|secretin receptor activity|peptide binding|,10,-0.3,1,10,0.3,1.47,0.3,0.304,0.304,0.79,0,0,-1.3,1.6
ENSMUSG00000024654,ASRGL1,asparaginase like 1,nucleus|cytoplasm|,proteolysis|asparagine catabolic process via L-aspartate|,asparaginase activity|peptidase activity|beta-aspartyl-peptidase activity|hydrolase activity|,10,0,0,10,0.2,0.948,0.1,0.3,0.3,0.791,0,0,-1.4,1.5
ENSMUSG00000028944,PRKAG2,"protein kinase, AMP-activated, gamma 2 non-catalytic subunit",extracellular space|AMP-activated protein kinase complex|,glycogen metabolic process|regulation of glycolytic process|protein phosphorylation|protein phosphorylation|negative regulation of protein kinase activity|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|positive regulation of peptidyl-threonine phosphorylation|phosphorylation|regulation of fatty acid metabolic process|intracellular signal transduction|positive regulation of protein kinase activity|regulation of catalytic activity|negative regulation of protein serine/threonine kinase activity|,nucleotide binding|AMP-activated protein kinase activity|AMP-activated protein kinase activity|cAMP-dependent protein kinase inhibitor activity|ATP binding|cAMP-dependent protein kinase regulator activity|phosphorylase kinase regulator activity|AMP binding|kinase activity|transferase activity|protein kinase binding|protein kinase activator activity|adenyl nucleotide binding|ADP binding|,10,-0.3,1.26,10,0,0,-0.2,0.297,-0.297,0.792,0,0,-1.5,1.4
ENSMUSG00000071521,TRY10,trypsin 10,extracellular vesicular exosome|blood microparticle|,proteolysis|biological_process|,molecular_function|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.1,0.815,-0.1,0.296,-0.296,0.793,0,0,-1,1.9
ENSMUSG00000041836,PTPRE,"protein tyrosine phosphatase, receptor type, E",nucleus|cytoplasm|cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|,protein dephosphorylation|transmembrane receptor protein tyrosine phosphatase signaling pathway|dephosphorylation|regulation of mast cell activation|peptidyl-tyrosine dephosphorylation|negative regulation of insulin receptor signaling pathway|negative regulation of insulin receptor signaling pathway|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|phosphatase activity|protein homodimerization activity|,10,-0.2,0.614,10,0.1,0.247,-0.1,0.29,-0.29,0.794,0,0,-1.6,1.2
ENSMUSG00000027249,F2,coagulation factor II,extracellular region|extracellular space|extracellular matrix|extracellular vesicular exosome|blood microparticle|,positive regulation of protein phosphorylation|proteolysis|acute-phase response|cell surface receptor signaling pathway|blood coagulation|hemostasis|positive regulation of cell proliferation|regulation of cell shape|response to wounding|regulation of gene expression|positive regulation of phosphatidylinositol 3-kinase signaling|platelet activation|platelet activation|positive regulation of blood coagulation|positive regulation of cell growth|positive regulation of collagen biosynthetic process|fibrinolysis|negative regulation of proteolysis|negative regulation of astrocyte differentiation|positive regulation of release of sequestered calcium ion into cytosol|cytosolic calcium ion homeostasis|thrombin receptor signaling pathway|positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of reactive oxygen species metabolic process|,catalytic activity|serine-type endopeptidase activity|serine-type endopeptidase activity|receptor binding|receptor binding|calcium ion binding|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|thrombospondin receptor activity|,10,0,0,10,0.2,0.59,0.3,0.288,0.288,0.795,0,0,-1.1,1.7
ENSMUSG00000029648,FLT1,FMS-like tyrosine kinase 1,endosome|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,angiogenesis|angiogenesis|patterning of blood vessels|sprouting angiogenesis|monocyte chemotaxis|protein phosphorylation|chemotaxis|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|positive regulation of phospholipase C activity|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|cell migration|cell migration|cell migration|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|cell differentiation|positive regulation of cell migration|positive regulation of vascular endothelial growth factor receptor signaling pathway|cellular response to vascular endothelial growth factor stimulus|vascular endothelial growth factor receptor-1 signaling pathway|vascular endothelial growth factor signaling pathway|positive regulation of MAP kinase activity|positive regulation of MAPK cascade|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of angiogenesis|protein autophosphorylation|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|blood vessel morphogenesis|embryonic morphogenesis|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|vascular endothelial growth factor-activated receptor activity|vascular endothelial growth factor-activated receptor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|VEGF-A-activated receptor activity|VEGF-B-activated receptor activity|placental growth factor-activated receptor activity|identical protein binding|",10,0.1,0.397,10,0,0,0.1,0.288,0.288,0.795,0,0,-0.9,1.9
ENSMUSG00000037798,MAT1A,"methionine adenosyltransferase I, alpha",cytosol|nuclear matrix|,S-adenosylmethionine biosynthetic process|one-carbon metabolic process|protein homooligomerization|protein tetramerization|protein homotetramerization|,nucleotide binding|magnesium ion binding|methionine adenosyltransferase activity|methionine adenosyltransferase activity|ATP binding|amino acid binding|transferase activity|identical protein binding|protein homodimerization activity|ADP binding|metal ion binding|protein dimerization activity|,10,-0.2,1.26,10,0,0,-0.1,0.286,-0.286,0.795,0,0,-1.9,0.9
ENSMUSG00000004933,MATK,megakaryocyte-associated tyrosine kinase,cytoplasm|membrane|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,0.521,10,-0.4,1.2,0.1,0.273,0.273,0.799,0,0,-1.4,1.4
ENSMUSG00000047250,PTGS1,prostaglandin-endoperoxide synthase 1,photoreceptor outer segment|nuclear envelope|cytoplasm|cytoplasm|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,prostaglandin biosynthetic process|prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|response to oxidative stress|learning|memory|regulation of blood pressure|negative regulation of norepinephrine secretion|sensory perception of pain|cyclooxygenase pathway|keratinocyte differentiation|negative regulation of epinephrine secretion|maintenance of blood-brain barrier|regulation of cell proliferation|positive regulation of vasoconstriction|positive regulation of smooth muscle contraction|oxidation-reduction process|,peroxidase activity|prostaglandin-endoperoxide synthase activity|lipid binding|oxidoreductase activity|heme binding|metal ion binding|dioxygenase activity|,10,0,0,10,0.4,1.76,0.2,0.273,0.273,0.799,0,0,-0.7,1.9
ENSMUSG00000037166,PPP1R14A,"protein phosphatase 1, regulatory (inhibitor) subunit 14A",cytoplasm|,regulation of phosphorylation|,protein phosphatase inhibitor activity|,10,0,0,10,-0.2,0.71,-0.1,0.263,-0.263,0.802,0,0,-1.6,1.2
ENSMUSG00000026399,CD55,CD55 antigen,plasma membrane|external side of plasma membrane|cell surface|membrane|apical plasma membrane|anchored component of membrane|membrane raft|extracellular vesicular exosome|,"immune system process|complement activation, classical pathway|response to virus|regulation of complement activation, classical pathway|negative regulation of catalytic activity|innate immune response|",virus receptor activity|enzyme inhibitor activity|lipid binding|,10,0.1,0.0424,10,-0.6,1.2,-0.3,0.261,-0.261,0.803,0,0,-1.9,0.8
ENSMUSG00000022571,PYCRL,pyrroline-5-carboxylate reductase-like,cellular_component|,proline biosynthetic process|cellular amino acid biosynthetic process|cytidine deamination|oxidation-reduction process|,cytidine deaminase activity|pyrroline-5-carboxylate reductase activity|protein binding|oxidoreductase activity|identical protein binding|,10,-0.1,0.0303,10,-0.2,0.328,-0.1,0.26,-0.26,0.803,0,0,-1.3,1.5
ENSMUSG00000020766,GALK1,galactokinase 1,cytoplasm|extracellular vesicular exosome|,carbohydrate metabolic process|galactose metabolic process|galactose metabolic process|galactose metabolic process|metabolic process|phosphorylation|galactitol metabolic process|carbohydrate phosphorylation|carbohydrate phosphorylation|,"nucleotide binding|galactokinase activity|galactokinase activity|protein binding|ATP binding|galactose binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|",9,0.7,0.738,9,0,0,0.1,0.26,0.26,0.803,0,0,-0.9,2
ENSMUSG00000027950,CHRNB2,"cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)",plasma membrane|plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|external side of plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,"action potential|action potential|conditioned taste aversion|response to hypoxia|response to hypoxia|transport|ion transport|cation transport|calcium ion transport|smooth muscle contraction|signal transduction|synaptic transmission, cholinergic|visual perception|sensory perception of sound|learning|learning|memory|memory|locomotory behavior|associative learning|visual learning|visual learning|regulation of dopamine secretion|sensory perception of pain|vestibulocochlear nerve development|optic nerve morphogenesis|lateral geniculate nucleus development|central nervous system projection neuron axonogenesis|central nervous system neuron axonogenesis|positive regulation of B cell proliferation|positive regulation of B cell proliferation|regulation of synaptic transmission, dopaminergic|positive regulation of synaptic transmission, dopaminergic|positive regulation of dopamine secretion|positive regulation of dopamine secretion|ion transmembrane transport|response to nicotine|response to nicotine|response to nicotine|behavioral response to nicotine|behavioral response to nicotine|social behavior|regulation of dopamine metabolic process|B cell activation|response to cocaine|regulation of circadian sleep/wake cycle, REM sleep|regulation of membrane potential|regulation of membrane potential|regulation of circadian sleep/wake cycle, non-REM sleep|response to ethanol|negative regulation of action potential|regulation of dendrite morphogenesis|neurological system process|cognition|protein heterooligomerization|membrane depolarization|regulation of synapse assembly|synaptic transmission involved in micturition|",acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|drug binding|acetylcholine receptor activity|acetylcholine binding|protein heterodimerization activity|,10,-0.1,0.176,10,-0.1,0.101,-0.1,0.253,-0.253,0.805,0,0,-1.6,1.3
ENSMUSG00000028480,GLIPR2,GLI pathogenesis-related 2,Golgi membrane|extracellular region|Golgi apparatus|membrane|extracellular vesicular exosome|,positive regulation of epithelial cell migration|positive regulation of epithelial to mesenchymal transition|positive regulation of ERK1 and ERK2 cascade|,protein homodimerization activity|,10,-0.1,0.101,10,-0.2,0.299,-0.1,0.252,-0.252,0.806,0,0,-2,0.8
ENSMUSG00000026688,MGST3,microsomal glutathione S-transferase 3,nuclear envelope|endoplasmic reticulum|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,oxidation-reduction process|oxidation-reduction process|,glutathione transferase activity|glutathione peroxidase activity|glutathione peroxidase activity|transferase activity|,10,1.3,2.53,10,0.1,0.343,0.1,0.25,0.25,0.806,0,0,-0.5,2
ENSMUSG00000020451,LIMK2,LIM motif-containing protein kinase 2,nucleus|nucleus|cytoplasm|cis-Golgi network|,protein phosphorylation|protein phosphorylation|spermatogenesis|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|zinc ion binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|protein heterodimerization activity|",10,-0.1,0.168,10,-0.1,0.105,-0.1,0.249,-0.249,0.807,0,0,-1.6,1.3
ENSMUSG00000027809,ETFDH,"electron transferring flavoprotein, dehydrogenase",mitochondrion|mitochondrial inner membrane|membrane|mitochondrial electron transfer flavoprotein complex|integral component of mitochondrial inner membrane|mitochondrial membrane|,transport|response to oxidative stress|electron transport chain|fatty acid beta-oxidation using acyl-CoA dehydrogenase|oxidation-reduction process|,"electron-transferring-flavoprotein dehydrogenase activity|electron carrier activity|oxidoreductase activity|metal ion binding|quinone binding|ubiquinone binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",9,0.3,0.707,9,-0.2,0.132,-0.2,0.247,-0.247,0.807,0,0,-1.4,1.5
ENSMUSG00000041440,GK5,glycerol kinase 5 (putative),cellular_component|,carbohydrate metabolic process|glycerol metabolic process|phosphorylation|,"nucleotide binding|glycerol kinase activity|ATP binding|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|",9,0,0,9,-0.5,0.682,-0.2,0.242,-0.242,0.808,0,0,-1.9,0.9
ENSMUSG00000025515,MUC2,mucin 2,extracellular region|proteinaceous extracellular matrix|inner mucus layer|outer mucus layer|,epithelial cell development|apoptotic process|negative regulation of cell proliferation|maintenance of gastrointestinal epithelium|negative regulation of cell migration|positive regulation of apoptotic process|,protein binding|,10,0.1,0.0205,10,0.1,0.244,0.1,0.242,0.242,0.808,0,0,-1.5,1.4
ENSMUSG00000041741,PDE3A,"phosphodiesterase 3A, cGMP inhibited",cytosol|membrane|integral component of membrane|,oocyte maturation|cAMP catabolic process|signal transduction|cAMP-mediated signaling|cGMP-mediated signaling|regulation of meiosis|response to drug|negative regulation of apoptotic process|negative regulation of vascular permeability|positive regulation of vascular permeability|positive regulation of oocyte development|cellular response to cGMP|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|cAMP binding|metal ion binding|",9,-0.4,0.519,9,0.2,0.699,0.2,0.237,0.237,0.81,0,0,-1.3,1.6
ENSMUSG00000005469,PRKACA,"protein kinase, cAMP dependent, catalytic, alpha",nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|Golgi apparatus|centrosome|plasma membrane|cilium|cAMP-dependent protein kinase complex|membrane|membrane|AMP-activated protein kinase complex|neuromuscular junction|cell projection|neuron projection|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|sperm midpiece|ciliary base|,"mesoderm formation|neural tube closure|protein phosphorylation|protein phosphorylation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|regulation of cellular respiration|regulation of osteoblast differentiation|protein autophosphorylation|positive regulation of protein export from nucleus|sperm capacitation|regulation of synaptic transmission|negative regulation of meiotic cell cycle|regulation of synaptic transmission, glutamatergic|regulation of proteasomal protein catabolic process|regulation of protein processing|positive regulation of cell cycle arrest|cellular response to glucose stimulus|cellular response to parathyroid hormone stimulus|negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|regulation of tight junction assembly|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cAMP-dependent protein kinase activity|cAMP-dependent protein kinase activity|protein serine/threonine/tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Rab GTPase binding|protein kinase binding|ubiquitin protein ligase binding|protein complex binding|protein kinase A regulatory subunit binding|",10,0,0,10,-0.2,0.59,-0.1,0.234,-0.234,0.811,0,0,-1.6,1.3
ENSMUSG00000073889,IL11RA1,"interleukin 11 receptor, alpha chain 1",membrane|integral component of membrane|,natural killer cell differentiation|placenta development|positive regulation of cell proliferation|cytokine-mediated signaling pathway|interleukin-11-mediated signaling pathway|decidualization|maternal process involved in female pregnancy|,cytokine receptor activity|interleukin-11 receptor activity|interleukin-11 binding|,10,0,0,10,0.1,0.336,0.1,0.231,0.231,0.812,0,0,-1.2,1.6
ENSMUSG00000089678,AGXT2,alanine-glyoxylate aminotransferase 2,mitochondrion|mitochondrion|,"glyoxylate catabolic process|glycine biosynthetic process, by transamination of glyoxylate|L-alanine catabolic process, by transamination|positive regulation of nitric oxide biosynthetic process|",catalytic activity|alanine-glyoxylate transaminase activity|transaminase activity|beta-alanine-pyruvate transaminase activity|transferase activity|pyridoxal phosphate binding|(R)-3-amino-2-methylpropionate-pyruvate transaminase activity|,10,0.2,0.943,10,-0.2,0.0805,0.1,0.227,0.227,0.813,0,0,-1.5,1.4
ENSMUSG00000028001,FGA,fibrinogen alpha chain,fibrinogen complex|extracellular space|cytoplasm|cell cortex|external side of plasma membrane|cell surface|platelet alpha granule|extracellular vesicular exosome|blood microparticle|,"cell-matrix adhesion|blood coagulation|positive regulation of heterotypic cell-cell adhesion|cellular protein complex assembly|positive regulation of vasoconstriction|positive regulation of exocytosis|positive regulation of protein secretion|protein polymerization|response to calcium ion|positive regulation of ERK1 and ERK2 cascade|platelet aggregation|blood coagulation, common pathway|positive regulation of peptide hormone secretion|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of endothelial cell apoptotic process|",receptor binding|structural molecule activity|cell adhesion molecule binding|,10,-0.3,0.776,10,0.1,0.326,-0.1,0.226,-0.226,0.813,0,0,-1.6,1.2
ENSMUSG00000074489,BGLAP3,bone gamma-carboxyglutamate protein 3,extracellular region|extracellular space|cytoplasm|rough endoplasmic reticulum|Golgi apparatus|dendrite|membrane-bounded vesicle|cell projection|perikaryon|,biological_process|regulation of bone mineralization|biomineral tissue development|,calcium ion binding|structural constituent of bone|,10,-0.2,0.78,10,0.1,0.197,-0.1,0.223,-0.223,0.814,0,0,-1.6,1.2
ENSMUSG00000054008,NDST1,N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1,intracellular|Golgi apparatus|membrane|integral component of membrane|,MAPK cascade|polysaccharide biosynthetic process|protein deacetylation|protein sulfation|protein sulfation|inflammatory response|smoothened signaling pathway|respiratory gaseous exchange|metabolic process|fibroblast growth factor receptor signaling pathway|embryo development|organ morphogenesis|glycosaminoglycan metabolic process|forebrain development|forebrain development|midbrain development|embryonic neurocranium morphogenesis|embryonic viscerocranium morphogenesis|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|catalytic activity|GPI-anchor transamidase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|[heparan sulfate]-glucosamine N-sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|hydrolase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|deacetylase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|hydroxyjasmonate sulfotransferase activity|",10,0.1,0.493,10,0,0,0.1,0.223,0.223,0.814,0,0,-1.2,1.7
ENSMUSG00000044453,FFAR1,free fatty acid receptor 1,cell|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of calcium ion transport into cytosol|insulin secretion|positive regulation of insulin secretion|glucose homeostasis|,signal transducer activity|G-protein coupled receptor activity|fatty acid binding|lipid binding|,10,0.1,0.00772,10,0.1,0.232,0.1,0.219,0.219,0.815,0,0,-1.2,1.7
ENSMUSG00000027301,OXT,oxytocin,extracellular region|extracellular space|cytoplasm|cytoplasm|secretory granule|terminal bouton|,regulation of heart rate|positive regulation of cytosolic calcium ion concentration|grooming behavior|positive regulation of norepinephrine secretion|response to organic cyclic compound|sleep|positive regulation of prostaglandin secretion|response to progesterone|social behavior|negative regulation of urine volume|positive regulation of renal sodium excretion|maternal behavior|sperm ejaculation|eating behavior|drinking behavior|regulation of digestive system process|negative regulation of blood pressure|positive regulation of blood pressure|positive regulation of ossification|positive regulation of female receptivity|positive regulation of synaptic transmission|regulation of sensory perception of pain|positive regulation of synapse assembly|positive regulation of penile erection|positive regulation of hindgut contraction|negative regulation of gastric acid secretion|positive regulation of uterine smooth muscle contraction|,hormone activity|neuropeptide hormone activity|neurohypophyseal hormone activity|oxytocin receptor binding|,10,0.1,0.0036,10,-0.1,0.485,-0.1,0.219,-0.219,0.815,0,0,-1.4,1.5
ENSMUSG00000016255,TUBB1,"tubulin, beta 1 class VI",cytoplasm|cytoskeleton|microtubule|protein complex|,GTP catabolic process|microtubule-based process|spindle assembly|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,0.3,0.838,10,-0.1,0.133,0.1,0.218,0.218,0.815,0,0,-1,1.8
ENSMUSG00000032584,MST1R,macrophage stimulating 1 receptor (c-met-related tyrosine kinase),stress fiber|plasma membrane|membrane|integral component of membrane|,immune system process|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|response to virus|response to virus|viral process|phosphorylation|positive regulation of MAP kinase activity|innate immune response|positive regulation of protein kinase B signaling|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|",10,-0.1,0.0402,10,-0.1,0.199,-0.1,0.218,-0.218,0.815,0,0,-1.8,1.2
ENSMUSG00000032384,CSNK1G1,"casein kinase 1, gamma 1",cytoplasm|,protein phosphorylation|Wnt signaling pathway|phosphorylation|protein autophosphorylation|,"nucleotide binding|magnesium ion binding|glycoprotein binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|peptide binding|phosphoprotein binding|",9,0.1,0.448,9,-0.1,0.125,0.1,0.217,0.217,0.815,0,0,-1.3,1.7
ENSMUSG00000074991,GABRR3,"gamma-aminobutyric acid (GABA) receptor, rho 3",plasma membrane|membrane|integral component of membrane|cell junction|synapse|,transport|ion transport|,protein domain specific binding|,10,0.4,1.61,10,-0.3,0.753,0.2,0.217,0.217,0.815,0,0,-1.2,1.6
ENSMUSG00000026726,CUBN,cubilin (intrinsic factor-cobalamin receptor),cytoplasm|lysosome|endosome|endoplasmic reticulum|Golgi apparatus|brush border|coated pit|coated pit|membrane|apical plasma membrane|apical plasma membrane|coated vesicle|endocytic vesicle|endocytic vesicle|endocytic vesicle membrane|brush border membrane|lysosomal lumen|protein complex|apical part of cell|extracellular vesicular exosome|,in utero embryonic development|lipid metabolic process|transport|receptor-mediated endocytosis|receptor-mediated endocytosis|response to nutrient|steroid metabolic process|cholesterol metabolic process|protein transport|cobalamin transport|hemoglobin import|lipoprotein transport|protein homotrimerization|,receptor activity|receptor activity|calcium ion binding|protein binding|cobalamin transporter activity|hemoglobin binding|cobalamin binding|identical protein binding|protein homodimerization activity|metal ion binding|,10,-0.2,0.378,10,0,0,-0.1,0.214,-0.214,0.816,0,0,-1.8,1
ENSMUSG00000030655,SMG1,"SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)",nucleus|cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|DNA repair|response to stress|cellular response to DNA damage stimulus|phosphorylation|peptidyl-serine phosphorylation|protein autophosphorylation|phosphatidylinositol phosphorylation|","nucleotide binding|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|poly(A) RNA binding|metal ion binding|",9,-0.1,0.476,9,0,0,-0.1,0.21,-0.21,0.817,0,0,-1.5,1.5
ENSMUSG00000059654,REG1,regenerating islet-derived 1,extracellular region|extracellular vesicular exosome|,None,growth factor activity|carbohydrate binding|,10,0,0,10,-0.3,0.542,-0.3,0.21,-0.21,0.817,0,0,-1.7,1
ENSMUSG00000026126,PTPN18,"protein tyrosine phosphatase, non-receptor type 18",nucleus|cytoplasm|,protein dephosphorylation|dephosphorylation|peptidyl-tyrosine dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|non-membrane spanning protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|,10,0,0,10,-0.2,0.665,-0.1,0.207,-0.207,0.818,0,0,-1.8,1.1
ENSMUSG00000075122,CD80,CD80 antigen,external side of plasma membrane|cell surface|membrane|integral component of membrane|,T cell costimulation|positive regulation of T cell proliferation|positive regulation of T cell proliferation|positive regulation of alpha-beta T cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|,protein binding|,10,0.6,2.93,10,-0.1,0.0758,0.5,0.197,0.197,0.821,0,0,-0.8,1.9
ENSMUSG00000028763,HSPG2,perlecan (heparan sulfate proteoglycan 2),extracellular region|proteinaceous extracellular matrix|basement membrane|basal lamina|extracellular space|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,angiogenesis|endochondral ossification|chondrocyte differentiation|brain development|protein localization|extracellular matrix organization|embryonic skeletal system morphogenesis|cardiac muscle tissue development|cartilage development involved in endochondral bone morphogenesis|,protease binding|protein binding|protein C-terminus binding|metal ion binding|,10,0,0,10,-0.2,0.483,-0.1,0.194,-0.194,0.822,0,0,-1.6,1.3
ENSMUSG00000060802,B2M,beta-2 microglobulin,extracellular region|extracellular space|cytoplasm|Golgi apparatus|plasma membrane|external side of plasma membrane|membrane|MHC class I protein complex|extracellular vesicular exosome|,"positive regulation of T cell mediated cytotoxicity|response to molecule of bacterial origin|immune system process|antigen processing and presentation of peptide antigen via MHC class I|antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent|cellular defense response|T cell differentiation in thymus|protein refolding|",protein binding|identical protein binding|,10,0.1,0.278,10,-0.2,0.705,-0.1,0.191,-0.191,0.823,0,0,-1.4,1.4
ENSMUSG00000025329,PADI1,"peptidyl arginine deiminase, type I",cytoplasm|extracellular vesicular exosome|,cellular protein modification process|protein citrullination|,protein-arginine deiminase activity|protein-arginine deiminase activity|calcium ion binding|hydrolase activity|,10,0,0,10,0.2,0.726,0.1,0.189,0.189,0.824,0,0,-1.7,1.2
ENSMUSG00000030345,DYRK4,dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4,cytoplasm|intracellular membrane-bounded organelle|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.8,1.05,10,0,0,-0.1,0.187,-0.187,0.824,0,0,-1.9,1.2
ENSMUSG00000042249,ADRBK2,"adrenergic receptor kinase, beta 2",nucleus|cytosol|cilium|membrane|Z disc|axon|dendritic spine|dendritic shaft|dendrite terminus|synapse|perinuclear region of cytoplasm|sperm midpiece|,positive regulation of protein phosphorylation|desensitization of G-protein coupled receptor protein signaling pathway|protein phosphorylation|protein phosphorylation|intracellular protein transport|signal transduction|phosphorylation|receptor internalization|termination of G-protein coupled receptor signaling pathway|inositol phosphate metabolic process|rhodopsin metabolic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|G-protein coupled receptor kinase activity|G-protein coupled receptor kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|D1 dopamine receptor binding|beta-adrenergic receptor kinase activity|",10,-0.1,0.144,10,0.1,0.208,0.1,0.186,0.186,0.825,0,0,-1.4,1.5
ENSMUSG00000017831,RAB5A,"RAB5A, member RAS oncogene family",ruffle|cytoplasm|cytoplasm|endosome|early endosome|early endosome|plasma membrane|plasma membrane|synaptic vesicle|actin cytoskeleton|membrane|endocytic vesicle|axon|dendrite|cytoplasmic vesicle|zymogen granule membrane|cell projection|neuron projection|neuronal cell body|terminal bouton|protein complex|membrane raft|phagocytic vesicle|perinuclear region of cytoplasm|recycling endosome|extracellular vesicular exosome|,GTP catabolic process|GTP catabolic process|transport|endocytosis|endocytosis|small GTPase mediated signal transduction|nervous system development|positive regulation of smooth muscle cell migration|protein transport|cell differentiation|positive regulation of exocytosis|regulation of long-term neuronal synaptic plasticity|positive regulation of smooth muscle cell proliferation|regulation of filopodium assembly|receptor internalization involved in canonical Wnt signaling pathway|,nucleotide binding|GTPase activity|GTPase activity|GTPase activity|protein binding|GTP binding|guanyl nucleotide binding|GDP binding|GDP-dissociation inhibitor binding|,10,-0.2,0.485,10,0.1,0.401,0.1,0.184,0.184,0.825,0,0,-1.4,1.5
ENSMUSG00000040990,SH3KBP1,SH3-domain kinase binding protein 1,cytoplasm|cytoskeleton|cell-cell junction|membrane|cell junction|cytoplasmic vesicle|neuron projection|synapse|,endocytosis|apoptotic process|cytoskeleton organization|regulation of cell shape|cell migration|,protein binding|SH3 domain binding|,10,0.1,0.186,10,-0.1,0.113,-0.1,0.184,-0.184,0.825,0,0,-1.5,1.4
ENSMUSG00000046410,KCNK6,"potassium inwardly-rectifying channel, subfamily K, member 6",cellular_component|membrane|integral component of membrane|,regulation of systemic arterial blood pressure|negative regulation of systemic arterial blood pressure|transport|ion transport|regulation of resting membrane potential|potassium ion transmembrane transport|,potassium channel activity|,10,-0.2,0.388,10,0.2,0.92,0.1,0.183,0.183,0.826,0,0,-1.1,1.7
ENSMUSG00000026785,PKN3,protein kinase N3,cellular_component|nucleus|cytoplasm|,protein phosphorylation|signal transduction|epithelial cell migration|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.5,0.963,10,0,0,0.4,0.18,0.18,0.827,0,0,-0.6,1.9
ENSMUSG00000029575,MMAB,methylmalonic aciduria (cobalamin deficiency) type B homolog (human),mitochondrion|,None,"nucleotide binding|ATP binding|cob(I)yrinic acid a,c-diamide adenosyltransferase activity|transferase activity|",9,0,0,9,0.2,0.473,0.1,0.176,0.176,0.828,0,0,-1.1,1.9
ENSMUSG00000006216,CLCNKB,chloride channel Kb,plasma membrane|membrane|integral component of membrane|chloride channel complex|,transport|ion transport|chloride transport|regulation of ion transmembrane transport|transmembrane transport|chloride transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|protein binding|adenyl nucleotide binding|metal ion binding|,10,0.1,0.267,10,-0.1,0.0785,0.1,0.17,0.17,0.83,0,0,-1.4,1.5
ENSMUSG00000052468,PMP2,peripheral myelin protein 2,cellular_component|cytoplasm|,transport|membrane organization|,transporter activity|fatty acid binding|lipid binding|cholesterol binding|,10,0.5,0.699,10,0,0,0.1,0.162,0.162,0.832,0,0,-0.9,1.9
ENSMUSG00000006675,P4HTM,"prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,oxidation-reduction process|,"sulfonate dioxygenase activity|molecular_function|iron ion binding|calcium ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|L-ascorbic acid binding|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0,0,10,-0.2,0.394,-0.1,0.161,-0.161,0.832,0,0,-1.7,1.1
ENSMUSG00000027963,EXTL2,exostoses (multiple)-like 2,endoplasmic reticulum|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|extracellular vesicular exosome|,N-acetylglucosamine metabolic process|UDP-N-acetylgalactosamine metabolic process|,"glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|alpha-1,4-N-acetylgalactosaminyltransferase activity|metal ion binding|",10,-0.1,0.127,10,0.2,1.06,0.1,0.16,0.16,0.833,0,0,-1,1.8
ENSMUSG00000018293,PFN1,profilin 1,nucleus|cytoplasm|cytoplasm|cytoskeleton|membrane|neuron projection|synapse|extracellular vesicular exosome|blood microparticle|,neural tube closure|regulation of transcription from RNA polymerase II promoter|regulation of actin polymerization or depolymerization|positive regulation of epithelial cell migration|actin cytoskeleton organization|negative regulation of actin filament polymerization|positive regulation of actin filament polymerization|negative regulation of actin filament bundle assembly|positive regulation of ATPase activity|sequestering of actin monomers|positive regulation of transcription from RNA polymerase II promoter|positive regulation of viral transcription|positive regulation of DNA metabolic process|positive regulation of stress fiber assembly|negative regulation of stress fiber assembly|positive regulation of ruffle assembly|,"adenyl-nucleotide exchange factor activity|actin binding|receptor binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|Rho GTPase binding|poly(A) RNA binding|proline-rich region binding|",2,0.2,0.368,1,-0.1,0.177,0.1,0.16,0.16,0.833,0,0,-1.7,2
ENSMUSG00000027001,DUSP19,dual specificity phosphatase 19,cytoplasm|,inactivation of MAPK activity|negative regulation of protein kinase activity|protein dephosphorylation|JNK cascade|dephosphorylation|positive regulation of MAPK cascade|positive regulation of JUN kinase activity|negative regulation of JUN kinase activity|positive regulation of protein kinase activity|negative regulation of JNK cascade|positive regulation of JNK cascade|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein kinase inhibitor activity|MAP-kinase scaffold activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|hydrolase activity|phosphatase activity|protein kinase activator activity|mitogen-activated protein kinase kinase binding|mitogen-activated protein kinase kinase kinase binding|,9,-0.2,0.655,10,0.2,0.163,0.1,0.158,0.158,0.833,0,0,-1.3,1.7
ENSMUSG00000027317,PPP1R14D,"protein phosphatase 1, regulatory (inhibitor) subunit 14D",cellular_component|cytoplasm|,regulation of protein dephosphorylation|regulation of phosphorylation|negative regulation of catalytic activity|,protein phosphatase inhibitor activity|,9,0,0,9,0.2,0.756,0.1,0.156,0.156,0.834,0,0,-1.5,1.7
ENSMUSG00000007591,TSSK4,testis-specific serine kinase 4,acrosomal vesicle|motile cilium|,protein phosphorylation|multicellular organismal development|spermatogenesis|phosphorylation|cell differentiation|positive regulation of CREB transcription factor activity|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.2,0.429,10,0,0,0.1,0.155,0.155,0.834,0,0,-0.9,1.9
ENSMUSG00000039556,PPP1R3F,"protein phosphatase 1, regulatory (inhibitor) subunit 3F",membrane|integral component of membrane|,regulation of glycogen biosynthetic process|regulation of glycogen (starch) synthase activity|,protein phosphatase binding|glycogen binding|,9,0.1,0.507,9,-0.2,0.0375,0.1,0.155,0.155,0.834,0,0,-1.4,1.6
ENSMUSG00000014453,BLK,B lymphoid kinase,plasma membrane|membrane|,protein phosphorylation|phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of insulin secretion|B cell receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.567,10,0,0,0.1,0.155,0.155,0.834,0,0,-1.9,1
ENSMUSG00000032238,RORA,RAR-related orphan receptor alpha,nucleus|nucleus|,"angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|xenobiotic metabolic process|nitric oxide biosynthetic process|regulation of smoothened signaling pathway|positive regulation vascular endothelial growth factor production|regulation of glucose metabolic process|regulation of steroid metabolic process|cerebellar Purkinje cell differentiation|cerebellar granule cell precursor proliferation|intracellular receptor signaling pathway|circadian regulation of gene expression|cellular response to sterol|muscle cell differentiation|regulation of circadian rhythm|positive regulation of circadian rhythm|regulation of macrophage activation|negative regulation of I-kappaB kinase/NF-kappaB signaling|steroid hormone mediated signaling pathway|negative regulation of fat cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cGMP metabolic process|rhythmic process|negative regulation of inflammatory response|regulation of transcription involved in cell fate commitment|regulation of transcription involved in cell fate commitment|triglyceride homeostasis|triglyceride homeostasis|cellular response to hypoxia|T-helper 17 cell differentiation|regulation of cholesterol homeostasis|",transcription corepressor binding|transcription coactivator binding|transcription coactivator binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|beta-catenin binding|transcription factor binding|oxysterol binding|zinc ion binding|sequence-specific DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|direct ligand regulated sequence-specific DNA binding transcription factor activity|,10,0,0,10,0.7,1.48,-0.1,0.153,-0.153,0.835,0,0,-0.7,2
ENSMUSG00000024661,FTH1,ferritin heavy chain 1,nucleus|mitochondrion|extracellular vesicular exosome|,iron ion transport|cellular iron ion homeostasis|intracellular sequestering of iron ion|negative regulation of fibroblast proliferation|oxidation-reduction process|,ferroxidase activity|ferric iron binding|oxidoreductase activity|metal ion binding|,10,0.2,0.891,10,-0.1,0.312,0.1,0.152,0.152,0.835,0,0,-1.4,1.5
ENSMUSG00000027297,LTK,leukocyte tyrosine kinase,intracellular|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,protein phosphorylation|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|cell proliferation|positive regulation of cardiac muscle cell apoptotic process|positive regulation of neuron projection development|phosphatidylinositol 3-kinase signaling|phosphorylation|negative regulation of apoptotic process|cellular response to retinoic acid|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0,0,9,0.2,0.371,0.1,0.145,0.145,0.837,0,0,-1,1.9
ENSMUSG00000067235,H2-Q10,"histocompatibility 2, Q region locus 10",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|cell surface|membrane|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,positive regulation of T cell mediated cytotoxicity|immune system process|antigen processing and presentation of peptide antigen via MHC class I|immune response|antigen processing and presentation|,receptor binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,-0.1,0.191,10,0.1,0.0941,-0.1,0.136,-0.136,0.839,0,0,-1.3,1.5
ENSMUSG00000067713,PRKAG1,"protein kinase, AMP-activated, gamma 1 non-catalytic subunit",nucleus|membrane|AMP-activated protein kinase complex|protein complex|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|positive regulation of gene expression|regulation of catalytic activity|protein heterooligomerization|,nucleotide binding|protein kinase activity|AMP-activated protein kinase activity|AMP-activated protein kinase activity|ATP binding|AMP binding|protein kinase binding|adenyl nucleotide binding|ADP binding|,10,-0.1,0.0633,10,-0.3,0.179,-0.1,0.135,-0.135,0.84,0,0,-1.7,1.2
ENSMUSG00000035203,EPN1,epsin 1,nucleus|cytoplasm|plasma membrane|coated pit|membrane|,in utero embryonic development|endocytosis|Notch signaling pathway|female pregnancy|embryonic organ development|,transcription factor binding|lipid binding|,10,-0.1,0.161,10,0.4,1.53,0.2,0.133,0.133,0.841,0,0,-1.2,1.7
ENSMUSG00000036551,AKAP14,A kinase (PRKA) anchor protein 14,sperm fibrous sheath|,biological_process|phosphorylation|,kinase activity|transferase activity|protein kinase A binding|,10,0,0,10,-0.2,0.486,-0.1,0.131,-0.131,0.841,0,0,-1.8,1.2
ENSMUSG00000041380,HTR2C,5-hydroxytryptamine (serotonin) receptor 2C,intracellular|plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,"behavioral fear response|cGMP biosynthetic process|cellular calcium ion homeostasis|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating serotonin receptor signaling pathway|phospholipase C-activating serotonin receptor signaling pathway|serotonin receptor signaling pathway|behavior|locomotory behavior|feeding behavior|feeding behavior|positive regulation of phosphatidylinositol biosynthetic process|positive regulation of gamma-aminobutyric acid secretion|positive regulation of acetylcholine secretion, neurotransmission|phospholipase D-activating G-protein coupled receptor signaling pathway|regulation of neurological system process|regulation of appetite|behavioral response to nicotine|negative regulation of locomotion|response to drug|regulation of corticotropin-releasing hormone secretion|positive regulation of vasoconstriction|negative regulation of dopamine metabolic process|inositol phosphate-mediated signaling|release of sequestered calcium ion into cytosol|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|regulation of sensory perception of pain|positive regulation of ERK1 and ERK2 cascade|","Gq/11-coupled serotonin receptor activity|signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|serotonin receptor activity|drug binding|serotonin binding|1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding|",10,0,0,10,-0.1,0.264,-0.1,0.127,-0.127,0.842,0,0,-1.4,1.5
ENSMUSG00000045038,PRKCE,"protein kinase C, epsilon",Golgi membrane|intracellular|cell|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|cytoskeleton|plasma membrane|membrane|perinuclear region of cytoplasm|cell periphery|,"macrophage activation involved in immune response|immune system process|protein phosphorylation|protein phosphorylation|cell cycle|cell adhesion|chemosensory behavior|positive regulation of epithelial cell migration|positive regulation of fibroblast migration|positive regulation of cell-substrate adhesion|positive regulation of cell-substrate adhesion|negative regulation of mitochondrial membrane potential|phosphorylation|regulation of lipid metabolic process|positive regulation of actin filament polymerization|lipopolysaccharide-mediated signaling pathway|positive regulation of insulin secretion|positive regulation of synaptic transmission, GABAergic|positive regulation of cytokinesis|intracellular signal transduction|locomotory exploration behavior|TRAM-dependent toll-like receptor 4 signaling pathway|negative regulation of apoptotic process|positive regulation of catalytic activity|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to morphine|positive regulation of MAPK cascade|positive regulation of MAPK cascade|regulation of peptidyl-tyrosine phosphorylation|positive regulation of lipid catabolic process|release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion into cytosol|cell division|negative regulation of mitochondrial calcium ion concentration|regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of mucus secretion|cellular response to ethanol|cellular response to hypoxia|positive regulation of wound healing|positive regulation of receptor activity|positive regulation of cellular glucuronidation|","nucleotide binding|actin monomer binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|calcium-independent protein kinase C activity|receptor binding|protein binding|ATP binding|enzyme activator activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SH3 domain binding|enzyme binding|protein kinase binding|receptor activator activity|ethanol binding|metal ion binding|14-3-3 protein binding|",10,0.2,1.02,10,0,0,0.1,0.124,0.124,0.843,0,0,-1.3,1.6
ENSMUSG00000025630,HPRT,hypoxanthine guanine phosphoribosyl transferase,cytoplasm|cytoplasm|cytosol|extracellular vesicular exosome|,response to amphetamine|purine nucleotide biosynthetic process|purine ribonucleoside salvage|purine ribonucleoside salvage|purine ribonucleoside salvage|adenine salvage|guanine salvage|guanine salvage|grooming behavior|locomotory behavior|nucleoside metabolic process|cytolysis|striatum development|cerebral cortex neuron differentiation|central nervous system neuron development|GMP salvage|IMP salvage|dopamine metabolic process|hypoxanthine salvage|positive regulation of dopamine metabolic process|positive regulation of dopamine metabolic process|GMP catabolic process|IMP metabolic process|adenine metabolic process|adenine metabolic process|hypoxanthine metabolic process|hypoxanthine metabolic process|hypoxanthine metabolic process|lymphocyte proliferation|dendrite morphogenesis|protein homotetramerization|,"nucleotide binding|magnesium ion binding|magnesium ion binding|hypoxanthine phosphoribosyltransferase activity|hypoxanthine phosphoribosyltransferase activity|hypoxanthine phosphoribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|identical protein binding|protein homodimerization activity|metal ion binding|guanine phosphoribosyltransferase activity|",10,-0.2,0.98,10,0,0,-0.1,0.123,-0.123,0.844,0,0,-1.5,1.4
ENSMUSG00000027360,HDC,histidine decarboxylase,cytosol|dendrite|neuronal cell body|,histamine metabolic process|histamine biosynthetic process|histamine biosynthetic process|cellular amino acid metabolic process|histidine metabolic process|histidine catabolic process|histidine catabolic process|histidine catabolic process|carboxylic acid metabolic process|catecholamine biosynthetic process|,catalytic activity|histidine decarboxylase activity|histidine decarboxylase activity|histidine decarboxylase activity|amino acid binding|lyase activity|carboxy-lyase activity|pyridoxal phosphate binding|,10,-0.1,0.566,10,0,0,-0.1,0.122,-0.122,0.844,0,0,-1.7,1.3
ENSMUSG00000024211,GRM8,"glutamate receptor, metabotropic 8",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|presynaptic membrane|presynaptic membrane|neuron projection|neuronal cell body|,"signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|synaptic transmission|synaptic transmission|sensory perception of smell|negative regulation of cAMP biosynthetic process|synaptic transmission, glutamatergic|synaptic transmission, glutamatergic|regulation of neurotransmitter secretion|response to stimulus|detection of mechanical stimulus involved in sensory perception of pain|regulation of synaptic transmission, glutamatergic|",group III metabotropic glutamate receptor activity|group III metabotropic glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|glutamate receptor activity|,10,-0.5,0.573,10,0,0,-0.1,0.116,-0.116,0.846,0,0,-1.9,0.9
ENSMUSG00000030137,TUBA8,"tubulin, alpha 8",cytoplasm|cytoskeleton|microtubule|protein complex|,microtubule cytoskeleton organization|GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,-0.1,0.335,10,0,0,-0.1,0.116,-0.116,0.846,0,0,-1.5,1.5
ENSMUSG00000034751,MAST4,microtubule associated serine/threonine kinase family member 4,cellular_component|cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.2,0.487,10,0.1,0.263,-0.1,0.113,-0.113,0.846,0,0,-1.8,1
ENSMUSG00000031337,MTM1,X-linked myotubular myopathy gene 1,ruffle|cytoplasm|cytoplasm|endosome|late endosome|plasma membrane|membrane|filopodium|I band|cell projection|extracellular vesicular exosome|,protein dephosphorylation|transport|endosome to lysosome transport|protein transport|dephosphorylation|regulation of vacuole organization|intermediate filament organization|muscle cell cellular homeostasis|phosphatidylinositol dephosphorylation|mitochondrion distribution|mitochondrion distribution|mitochondrion morphogenesis|mitochondrion morphogenesis|,"phosphatidylinositol-3-phosphatase activity|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|intermediate filament binding|phosphatidylinositol binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|",10,-0.1,0.0793,10,-0.1,0.0422,-0.1,0.111,-0.111,0.847,0,0,-1.5,1.4
ENSMUSG00000062312,ERBB2,"v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)",nucleus|cytoplasm|cytoplasm|plasma membrane|plasma membrane|microvillus|basal plasma membrane|endosome membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|cytoplasmic vesicle|lateral loop|receptor complex|membrane raft|postsynaptic membrane|perinuclear region of cytoplasm|,"positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|signal transduction|cell surface receptor signaling pathway|transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|peripheral nervous system development|peripheral nervous system development|heart development|neuromuscular junction development|motor neuron axon guidance|positive regulation of cell proliferation|glial cell differentiation|phosphatidylinositol 3-kinase signaling|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of cell growth|positive regulation of Rho GTPase activity|regulation of microtubule-based process|negative regulation of immature T cell proliferation in thymus|wound healing|myelination|negative regulation of apoptotic process|positive regulation of MAP kinase activity|positive regulation of MAPK cascade|positive regulation of translation|positive regulation of cell adhesion|positive regulation of transcription from RNA polymerase I promoter|positive regulation of transcription from RNA polymerase III promoter|positive regulation of Ras protein signal transduction|protein autophosphorylation|sympathetic nervous system development|response to axon injury|oligodendrocyte differentiation|positive regulation of epithelial cell proliferation|estrus|regulation of ERK1 and ERK2 cascade|","nucleotide binding|RNA polymerase I core binding|glycoprotein binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity|transmembrane signaling receptor activity|protein binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|protein phosphatase binding|ubiquitin protein ligase binding|identical protein binding|protein heterodimerization activity|Hsp90 protein binding|",10,0.1,0.0124,10,-0.1,0.126,-0.1,0.106,-0.106,0.849,0,0,-1.7,1.2
ENSMUSG00000040808,S100G,S100 calcium binding protein G,basolateral plasma membrane|apical plasma membrane|,None,vitamin D binding|calcium ion binding|metal ion binding|,7,0.2,0.478,7,0,0,0.1,0.0936,0.0936,0.852,0,0,-1.3,1.9
ENSMUSG00000017969,PTGIS,prostaglandin I2 (prostacyclin) synthase,extracellular space|nucleus|endoplasmic reticulum|endoplasmic reticulum|caveola|membrane|integral component of membrane|,prostaglandin biosynthetic process|prostaglandin biosynthetic process|response to hypoxia|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|negative regulation of NF-kappaB transcription factor activity|positive regulation of peroxisome proliferator activated receptor signaling pathway|regulation of apoptotic process|negative regulation of nitric oxide biosynthetic process|positive regulation of angiogenesis|negative regulation of inflammatory response|oxidation-reduction process|cellular response to hypoxia|apoptotic signaling pathway|positive regulation of execution phase of apoptosis|,"monooxygenase activity|iron ion binding|prostaglandin-I synthase activity|prostaglandin-I synthase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|isomerase activity|heme binding|heme binding|metal ion binding|",9,-0.9,2.12,8,0.1,0.179,0.1,0.0922,0.0922,0.852,0,0,-2,0.9
ENSMUSG00000037251,POMK,protein-O-mannose kinase,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,neuron migration|protein phosphorylation|protein O-linked glycosylation|brain development|learning or memory|phosphorylation|sensory perception of pain|carbohydrate phosphorylation|carbohydrate phosphorylation|neuromuscular process|,"nucleotide binding|protein kinase activity|ATP binding|phosphofructokinase activity|phosphorylase kinase regulator activity|cobinamide kinase activity|phytol kinase activity|kinase activity|phosphatidylinositol phosphate kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphotransferase activity, alcohol group as acceptor|phenol kinase activity|carbohydrate kinase activity|cyclin-dependent protein kinase activating kinase regulator activity|inositol tetrakisphosphate 2-kinase activity|heptose 7-phosphate kinase activity|aminoglycoside phosphotransferase activity|phosphatidylinositol 3-kinase activity|eukaryotic elongation factor-2 kinase regulator activity|eukaryotic elongation factor-2 kinase activator activity|LPPG:FO 2-phospho-L-lactate transferase activity|cytidine kinase activity|glycerate 2-kinase activity|(S)-lactate 2-kinase activity|phosphoserine:homoserine phosphotransferase activity|L-seryl-tRNA(Sec) kinase activity|phosphocholine transferase activity|polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide kinase activity|GTP-dependent polynucleotide kinase activity|farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|geraniol kinase activity|geranylgeraniol kinase activity|CTP:geranylgeraniol kinase activity|prenol kinase activity|1-phosphatidylinositol-5-kinase activity|1-phosphatidylinositol-3-phosphate 4-kinase activity|phosphatidylinositol-3,4-bisphosphate 5-kinase activity|phosphatidylinositol bisphosphate kinase activity|inositol-3,4,6-trisphosphate 1-kinase activity|inositol 5-diphosphate pentakisphosphate 5-kinase activity|inositol diphosphate tetrakisphosphate kinase activity|",10,0.3,0.181,10,0.1,0.0441,0.1,0.0909,0.0909,0.853,0,0,-1.4,1.5
ENSMUSG00000031443,F7,coagulation factor VII,extracellular region|extracellular space|vesicle|,positive regulation of leukocyte chemotaxis|proteolysis|blood coagulation|blood coagulation|hemostasis|positive regulation of platelet-derived growth factor receptor signaling pathway|positive regulation of blood coagulation|positive regulation of positive chemotaxis|positive regulation of protein kinase B signaling|,glycoprotein binding|catalytic activity|endopeptidase activity|serine-type endopeptidase activity|receptor binding|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.4,0.667,10,-0.2,0.74,-0.1,0.0907,-0.0907,0.853,0,0,-1.5,1.5
ENSMUSG00000012777,ACPT,"acid phosphatase, testicular",cellular_component|,biological_process|,molecular_function|,9,0.5,2.02,9,-0.2,0.303,-0.1,0.0893,-0.0893,0.853,0,0,-1.2,1.7
ENSMUSG00000032715,TRIB3,tribbles homolog 3 (Drosophila),nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|negative regulation of protein kinase activity|negative regulation of protein kinase activity|apoptotic process|regulation of glucose transport|positive regulation of protein binding|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular response to insulin stimulus|response to endoplasmic reticulum stress|regulation of MAP kinase activity|negative regulation of fat cell differentiation|negative regulation of fatty acid biosynthetic process|positive regulation of protein catabolic process|negative regulation of transcription, DNA-templated|positive regulation of ubiquitin-protein transferase activity|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of RNA biosynthetic process|","transcription corepressor activity|protein kinase activity|protein kinase inhibitor activity|protein binding|ATP binding|transferase activity, transferring phosphorus-containing groups|enzyme binding|protein kinase binding|protein kinase binding|ubiquitin protein ligase binding|ubiquitin protein ligase binding|ubiquitin-protein transferase regulator activity|",10,0,0,10,0.8,3.18,0.8,0.087,0.087,0.854,0,0,-0.6,2
ENSMUSG00000068227,IL2RB,"interleukin 2 receptor, beta chain",external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|,cytokine-mediated signaling pathway|natural killer cell activation|interleukin-2-mediated signaling pathway|negative regulation of apoptotic process|,cytokine receptor activity|interleukin-2 receptor activity|interleukin-2 binding|interleukin-2 binding|,10,-0.2,0.202,9,0,0,-0.1,0.0827,-0.0827,0.855,0,0,-1.4,1.7
ENSMUSG00000026354,LCT,lactase,brush border|,response to hypoxia|response to nutrient|metabolic process|response to organic substance|response to iron(II) ion|response to nickel cation|response to lead ion|response to drug|response to ethanol|,"lactase activity|transferase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",9,-0.5,2.26,9,0,0,-0.4,0.0822,-0.0822,0.855,0,0,-1.8,1.2
ENSMUSG00000020838,SLC6A4,"solute carrier family 6 (neurotransmitter transporter, serotonin), member 4",endosome|cytosol|plasma membrane|integral component of plasma membrane|endomembrane system|membrane|integral component of membrane|neuron projection|membrane raft|,"transport|neurotransmitter transport|serotonin transport|serotonin transport|memory|circadian rhythm|response to toxic substance|positive regulation of gene expression|monoamine transport|thalamus development|negative regulation of cerebellar granule cell precursor proliferation|negative regulation of synaptic transmission, dopaminergic|social behavior|sodium ion transmembrane transport|vasoconstriction|sperm ejaculation|negative regulation of neuron differentiation|positive regulation of cell cycle|negative regulation of organ growth|brain morphogenesis|protein oligomerization|protein homooligomerization|serotonin uptake|serotonin uptake|serotonin uptake|cellular response to organic substance|cellular response to cGMP|",neurotransmitter:sodium symporter activity|serotonin:sodium symporter activity|protein binding|monoamine transmembrane transporter activity|serotonin transmembrane transporter activity|symporter activity|myosin binding|syntaxin-1 binding|Rab GTPase binding|cocaine binding|protein homodimerization activity|nitric-oxide synthase binding|actin filament binding|,10,0.2,0.318,10,0,0,0.1,0.0801,0.0801,0.856,0,0,-1,1.9
ENSMUSG00000025648,PFKFB4,"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4",cellular_component|,"fructose metabolic process|fructose 2,6-bisphosphate metabolic process|metabolic process|phosphorylation|dephosphorylation|carbohydrate phosphorylation|","nucleotide binding|catalytic activity|6-phosphofructo-2-kinase activity|fructose-2,6-bisphosphate 2-phosphatase activity|ATP binding|kinase activity|transferase activity|hydrolase activity|",10,-0.3,0.096,10,-0.1,0.1,-0.1,0.0768,-0.0768,0.857,0,0,-1.8,1.1
ENSMUSG00000028463,CAR9,carbonic anhydrase 9,plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|cell projection|,morphogenesis of an epithelium|one-carbon metabolic process|secretion|,carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,-0.9,1.36,10,0.3,1.68,-0.1,0.0765,-0.0765,0.857,0,0,-2,0.8
ENSMUSG00000063856,GPX1,glutathione peroxidase 1,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrion|extracellular vesicular exosome|,"response to reactive oxygen species|temperature homeostasis|endothelial cell development|negative regulation of inflammatory response to antigenic stimulus|lipid metabolic process|triglyceride metabolic process|glutathione metabolic process|apoptotic process|response to oxidative stress|response to oxidative stress|response to lipid hydroperoxide|sensory perception of sound|cell proliferation|intrinsic apoptotic signaling pathway in response to oxidative stress|response to xenobiotic stimulus|response to symbiotic bacterium|response to wounding|response to toxic substance|UV protection|response to selenium ion|response to gamma radiation|myotube differentiation|protein oxidation|response to hydroperoxide|regulation of mammary gland epithelial cell proliferation|regulation of gene expression, epigenetic|vasodilation|response to hydrogen peroxide|response to hydrogen peroxide|hydrogen peroxide catabolic process|hydrogen peroxide catabolic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|skeletal muscle tissue regeneration|regulation of neuron apoptotic process|blood vessel endothelial cell migration|fat cell differentiation|cell redox homeostasis|skeletal muscle fiber development|myoblast proliferation|interaction with symbiont|positive regulation of protein kinase B signaling|oxidation-reduction process|heart contraction|heart contraction|angiogenesis involved in wound healing|regulation of proteasomal protein catabolic process|negative regulation of release of cytochrome c from mitochondria|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|",peroxidase activity|glutathione peroxidase activity|glutathione peroxidase activity|glutathione peroxidase activity|protein binding|selenium binding|oxidoreductase activity|SH3 domain binding|glutathione binding|phospholipid-hydroperoxide glutathione peroxidase activity|,9,0,0,9,-0.7,2.2,-0.1,0.0746,-0.0746,0.858,0,0,-2,0.7
ENSMUSG00000048480,CXCR1,chemokine (C-X-C motif) receptor 1,plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|receptor internalization|interleukin-8-mediated signaling pathway|chemokine-mediated signaling pathway|,signal transducer activity|interleukin-8 receptor activity|G-protein coupled receptor activity|chemokine receptor activity|C-X-C chemokine receptor activity|interleukin-8 binding|,10,0,0,10,-0.1,0.431,-0.1,0.0704,-0.0704,0.859,0,0,-1.8,1.1
ENSMUSG00000024527,AFG3L2,AFG3-like AAA ATPase 2,mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,proteolysis|mitochondrion organization|axonogenesis|neuromuscular junction development|mitochondrial fusion|death|nerve development|mitochondrial protein processing|regulation of multicellular organism growth|cristae formation|myelination|muscle fiber development|righting reflex|,nucleotide binding|metalloendopeptidase activity|ATP binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.2,0.591,10,0,0,0.1,0.066,0.066,0.86,0,0,-1.1,1.7
ENSMUSG00000027584,OPRL1,opioid receptor-like 1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|behavior|sensory perception of pain|opioid receptor signaling pathway|opioid receptor signaling pathway|,nociceptin receptor activity|nociceptin receptor activity|signal transducer activity|G-protein coupled receptor activity|opioid receptor activity|,10,0.3,1.17,10,0,0,0.1,0.0633,0.0633,0.861,0,0,-1.1,1.8
ENSMUSG00000041550,SERPINA5,"serine (or cysteine) peptidase inhibitor, clade A, member 5",acrosomal membrane|extracellular region|extracellular space|external side of plasma membrane|membrane|platelet alpha granule|platelet dense tubular network|protein C inhibitor-TMPRSS7 complex|protein C inhibitor-TMPRSS11E complex|protein C inhibitor-PLAT complex|protein C inhibitor-PLAU complex|protein C inhibitor-thrombin complex|protein C inhibitor-KLK3 complex|protein C inhibitor-plasma kallikrein complex|protein complex|extracellular vesicular exosome|protein C inhibitor-coagulation factor V complex|protein C inhibitor-coagulation factor Xa complex|protein C inhibitor-coagulation factor XI complex|,spermatogenesis|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|negative regulation of proteolysis|,retinoic acid binding|protease binding|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|protein binding|peptidase inhibitor activity|phosphatidylcholine binding|acrosin binding|,10,0,0,10,-0.1,0.0786,-0.1,0.061,-0.061,0.861,0,0,-1.5,1.4
ENSMUSG00000042717,PPP1R3A,"protein phosphatase 1, regulatory (inhibitor) subunit 3A",membrane|integral component of membrane|,carbohydrate metabolic process|glycogen metabolic process|dephosphorylation|,protein serine/threonine phosphatase activity|,10,-0.1,8.15E-05,10,0.2,1.21,0.1,0.0583,0.0583,0.862,0,0,-0.9,1.9
ENSMUSG00000089989,FLT3L,FMS-like tyrosine kinase 3 ligand,extracellular region|extracellular space|plasma membrane|cell surface|membrane|integral component of membrane|intrinsic component of external side of plasma membrane|,positive regulation of protein phosphorylation|positive regulation of cell proliferation|positive regulation of cell proliferation|phosphorylation|lymphocyte differentiation|regulation of myeloid dendritic cell activation|positive regulation of natural killer cell differentiation|embryonic hemopoiesis|,cytokine activity|kinase activity|transferase activity|receptor tyrosine kinase binding|receptor tyrosine kinase binding|protein homodimerization activity|,1,0,0,1,0.2,0.255,0.1,0.0582,0.0582,0.862,0,0,-1.8,2
ENSMUSG00000041629,FAM104A,"family with sequence similarity 104, member A",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.528,10,0,0,-0.1,0.0554,-0.0554,0.863,0,0,-1.4,1.5
ENSMUSG00000040424,HIPK4,homeodomain interacting protein kinase 4,nucleus|cytoplasm|,protein phosphorylation|phosphorylation|histone phosphorylation|peptidyl-serine phosphorylation|protein autophosphorylation|regulation of signal transduction by p53 class mediator|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.0341,10,0.1,0.0189,0.1,0.0482,0.0482,0.865,0,0,-1.3,1.6
ENSMUSG00000066072,CYP4A10,"cytochrome P450, family 4, subfamily a, polypeptide 10",cytoplasm|endoplasmic reticulum|membrane|apical plasma membrane|intracellular membrane-bounded organelle|intracellular membrane-bounded organelle|extracellular vesicular exosome|,fatty acid metabolic process|leukotriene B4 catabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|arachidonic acid monooxygenase activity|arachidonic acid epoxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|alkane 1-monooxygenase activity|heme binding|metal ion binding|leukotriene-B4 20-monooxygenase activity|arachidonic acid omega-hydroxylase activity|",10,-0.1,0.343,10,0,0,-0.1,0.0402,-0.0402,0.867,0,0,-1.7,1.3
ENSMUSG00000021180,RPS6KA5,"ribosomal protein S6 kinase, polypeptide 5",nucleus|nucleus|cytoplasm|,"regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|response to stress|inflammatory response|phosphorylation|histone phosphorylation|positive regulation of histone phosphorylation|positive regulation of histone acetylation|intracellular signal transduction|intracellular signal transduction|histone H3-S10 phosphorylation|histone H3-S10 phosphorylation|histone H3-S28 phosphorylation|histone H3-S28 phosphorylation|histone H2A-S1 phosphorylation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of NF-kappaB transcription factor activity|interleukin-1-mediated signaling pathway|","nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.0768,10,-0.6,0.141,0.1,0.0369,0.0369,0.869,0,0,-1.8,1.3
ENSMUSG00000056258,KCNQ3,"potassium voltage-gated channel, subfamily Q, member 3",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|node of Ranvier|axon initial segment|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|transmembrane transport|membrane hyperpolarization|potassium ion transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.1,0.0878,10,0.1,0.36,0.1,0.0353,0.0353,0.869,0,0,-1.3,1.6
ENSMUSG00000047654,TSSK6,testis-specific serine kinase 6,nucleus|,protein phosphorylation|multicellular organismal development|spermatogenesis|phosphorylation|cell differentiation|sperm chromatin condensation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.3,0.971,10,0,0,-0.1,0.0312,-0.0312,0.87,0,0,-1.8,1
ENSMUSG00000019577,PDK4,"pyruvate dehydrogenase kinase, isoenzyme 4",mitochondrion|mitochondrion|mitochondrial inner membrane|,carbohydrate metabolic process|glucose metabolic process|acetyl-CoA biosynthetic process from pyruvate|protein phosphorylation|protein phosphorylation|regulation of pH|insulin receptor signaling pathway|insulin receptor signaling pathway|cellular response to starvation|regulation of acetyl-CoA biosynthetic process from pyruvate|regulation of acetyl-CoA biosynthetic process from pyruvate|regulation of cellular ketone metabolic process|regulation of glucose metabolic process|regulation of glucose metabolic process|phosphorylation|regulation of fatty acid biosynthetic process|regulation of fatty acid biosynthetic process|glucose homeostasis|response to starvation|regulation of bone resorption|regulation of fatty acid oxidation|cellular response to fatty acid|reactive oxygen species metabolic process|negative regulation of anoikis|,nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|pyruvate dehydrogenase (acetyl-transferring) kinase activity|ATP binding|kinase activity|transferase activity|,10,0.2,0.284,10,0,0,0.1,0.0297,0.0297,0.871,0,0,-1.4,1.5
ENSMUSG00000047562,MMP10,matrix metallopeptidase 10,extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|regulation of cell migration|collagen catabolic process|,metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.2,0.164,10,0,0,0.1,0.0293,0.0293,0.871,0,0,-1.2,1.9
ENSMUSG00000031304,IL2RG,"interleukin 2 receptor, gamma chain",external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|,"regulation of gene expression|positive regulation of gene expression|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of T cell differentiation in thymus|positive regulation of B cell differentiation|positive regulation of lymphocyte differentiation|",cytokine receptor activity|interleukin-2 binding|interleukin-2 binding|interleukin-7 binding|,4,0,0,4,-0.4,0.578,-0.1,0.0293,-0.0293,0.871,0,0,-2,1.5
ENSMUSG00000037759,PTGER2,prostaglandin E receptor 2 (subtype EP2),plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|response to lipopolysaccharide|regulation of cell proliferation|cellular response to prostaglandin E stimulus|,signal transducer activity|G-protein coupled receptor activity|prostaglandin E receptor activity|,10,0.1,0.161,10,0,0,0.1,0.0262,0.0262,0.872,0,0,-1,1.9
ENSMUSG00000026163,SPHKAP,"SPHK1 interactor, AKAP domain containing",cytoplasm|mitochondrion|Z disc|extracellular vesicular exosome|,biological_process|,protein kinase A binding|protein kinase A binding|,10,0.4,0.3,10,0,0,0.3,0.0261,0.0261,0.872,0,0,-0.8,1.9
ENSMUSG00000055540,EPHA6,Eph receptor A6,nucleus|integral component of plasma membrane|membrane|integral component of membrane|,protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|phosphorylation|ephrin receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.185,10,-0.1,0.265,0.1,0.023,0.023,0.873,0,0,-1.4,1.5
ENSMUSG00000054934,KCNMB4,"potassium large conductance calcium-activated channel, subfamily M, beta member 4",integral component of plasma membrane|integral component of plasma membrane|voltage-gated potassium channel complex|voltage-gated potassium channel complex|membrane|integral component of membrane|,action potential|detection of calcium ion|transport|ion transport|potassium ion transport|neuronal action potential|potassium ion transmembrane transport|potassium ion transmembrane transport|,potassium channel activity|calcium-activated potassium channel activity|calcium-activated potassium channel activity|,10,0.6,1.22,10,0,0,0.1,0.0228,0.0228,0.873,0,0,-1,1.9
ENSMUSG00000026490,CDC42BPA,CDC42 binding protein kinase alpha,cell|cytoplasm|cell-cell junction|cell leading edge|actomyosin|extracellular vesicular exosome|,microtubule cytoskeleton organization|protein phosphorylation|cytoskeleton organization|nuclear migration|phosphorylation|cell migration|actomyosin structure organization|actin cytoskeleton reorganization|intracellular signal transduction|regulation of small GTPase mediated signal transduction|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|metal ion binding|",10,0.2,0.234,10,-0.2,0.445,-0.1,0.0222,-0.0222,0.873,0,0,-1.2,1.6
ENSMUSG00000049382,KRT8,keratin 8,nucleus|cytoplasm|intermediate filament|intermediate filament|cell-cell junction|dystrophin-associated glycoprotein complex|Z disc|Z disc|sarcolemma|sarcolemma|costamere|keratin filament|extracellular vesicular exosome|cell periphery|,cell morphogenesis involved in differentiation|multicellular organismal development|tumor necrosis factor-mediated signaling pathway|tumor necrosis factor-mediated signaling pathway|sarcomere organization|response to hydrostatic pressure|response to other organism|cell differentiation involved in embryonic placenta development|extrinsic apoptotic signaling pathway|hepatocyte apoptotic process|,structural molecule activity|protein binding|protein complex binding|scaffold protein binding|,10,-0.3,0.404,10,0.3,1.08,0.2,0.0207,0.0207,0.873,0,0,-1.1,1.8
ENSMUSG00000074375,SULT2A3,"sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3",cellular_component|cytoplasm|cytosol|,biological_process|,alcohol sulfotransferase activity|drug binding|sulfotransferase activity|transferase activity|3'-phosphoadenosine 5'-phosphosulfate binding|,10,0.2,0.602,10,0,0,0.1,0.0197,0.0197,0.873,0,0,-1.3,1.7
ENSMUSG00000067336,BMPR2,"bone morphogenetic protein receptor, type II (serine/threonine kinase)",extracellular space|cytoplasm|plasma membrane|integral component of plasma membrane|caveola|caveola|basal plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|dendrite|neuronal cell body|,mesoderm formation|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|lymphangiogenesis|blood vessel remodeling|chondrocyte development|negative regulation of systemic arterial blood pressure|transcription from RNA polymerase II promoter|protein phosphorylation|transmembrane receptor protein serine/threonine kinase signaling pathway|anterior/posterior pattern specification|anterior/posterior pattern specification|positive regulation of endothelial cell migration|positive regulation of epithelial cell migration|positive regulation of pathway-restricted SMAD protein phosphorylation|regulation of lung blood pressure|regulation of lung blood pressure|phosphorylation|negative regulation of cell growth|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|positive regulation of BMP signaling pathway|regulation of cell proliferation|positive regulation of osteoblast differentiation|negative regulation of vasoconstriction|vascular endothelial growth factor receptor signaling pathway|lung alveolus development|positive regulation of axon extension involved in axon guidance|limb development|lymphatic endothelial cell differentiation|artery development|venous blood vessel development|retina vasculature development in camera-type eye|negative regulation of chondrocyte proliferation|negative regulation of DNA biosynthetic process|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|transforming growth factor beta-activated receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|metal ion binding|",10,-0.5,0.454,10,0.2,0.511,-0.1,0.0153,-0.0153,0.875,0,0,-1.7,1.2
ENSMUSG00000057914,CACNB2,"calcium channel, voltage-dependent, beta 2 subunit",plasma membrane|voltage-gated calcium channel complex|voltage-gated calcium channel complex|membrane|,transport|ion transport|calcium ion transport|synaptic transmission|visual perception|regulation of ion transmembrane transport|positive regulation of calcium ion transport|calcium ion import|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel regulator activity|calcium channel activity|protein binding|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|protein kinase binding|protein domain specific binding|phosphoprotein binding|,10,0,0,10,-0.2,0.602,-0.1,0.0106,-0.0106,0.876,0,0,-1.7,1.2
ENSMUSG00000040936,ULK4,unc-51-like kinase 4,cellular_component|,epithelial cilium movement|protein phosphorylation|phosphorylation|ventricular system development|cilium morphogenesis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0,0,9,-0.1,0.227,-0.1,0.00991,-0.00991,0.876,0,0,-1.8,1.3
ENSMUSG00000022041,CHRNA2,"cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)",plasma membrane|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|cell periphery|,transport|ion transport|cation transport|signal transduction|synaptic transmission|ion transmembrane transport|protein heterooligomerization|,acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|drug binding|acetylcholine receptor activity|acetylcholine binding|,10,0.2,0.664,10,0,0,0.1,0.00897,0.00897,0.877,0,0,-1.2,1.7
ENSMUSG00000037738,NEK5,NIMA (never in mitosis gene a)-related expressed kinase 5,cellular_component|,protein phosphorylation|phosphorylation|positive regulation of striated muscle cell differentiation|positive regulation of cysteine-type endopeptidase activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0,0,10,0.4,0.95,0.1,0.00805,0.00805,0.877,0,0,-1.1,1.8
ENSMUSG00000060600,ENO3,"enolase 3, beta muscle",phosphopyruvate hydratase complex|extracellular space|cytoplasm|plasma membrane|membrane|,glycolytic process|,magnesium ion binding|phosphopyruvate hydratase activity|phosphopyruvate hydratase activity|lyase activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,9,0.1,0.0923,9,-0.1,0.316,-0.1,0.00781,-0.00781,0.877,0,0,-1.6,1.4
ENSMUSG00000023019,GPD1,glycerol-3-phosphate dehydrogenase 1 (soluble),intracellular|cell|cytoplasm|mitochondrion|cytosol|glycerol-3-phosphate dehydrogenase complex|extracellular vesicular exosome|,carbohydrate metabolic process|glycerol-3-phosphate metabolic process|glycerol-3-phosphate metabolic process|gluconeogenesis|NADH oxidation|glycerophosphate shuttle|NADH metabolic process|positive regulation of glycolytic process|glycerol-3-phosphate catabolic process|glycerolipid metabolic process|oxidation-reduction process|cellular response to cAMP|cellular response to tumor necrosis factor|,"glycerol-3-phosphate dehydrogenase [NAD+] activity|glycerol-3-phosphate dehydrogenase [NAD+] activity|glycerol-3-phosphate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|protein homodimerization activity|coenzyme binding|NAD binding|",10,-0.2,0.52,10,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000036401,GLT6D1,glycosyltransferase 6 domain containing 1,cellular_component|membrane|integral component of membrane|,carbohydrate metabolic process|biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",9,0,0,10,0,0,0,0,0,0.879,0,0,-1.4,1.8
ENSMUSG00000064090,VRK2,vaccinia related kinase 2,nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|mitochondrial membrane|,protein phosphorylation|phosphorylation|cellular response to oxidative stress|regulation of MAPK cascade|protein autophosphorylation|protein autophosphorylation|regulation of interleukin-1-mediated signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.19,10,0,0,0,0,0,0.879,0,0,-1.6,1.3
ENSMUSG00000010663,FADS1,fatty acid desaturase 1,nucleus|mitochondrion|endoplasmic reticulum|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|unsaturated fatty acid biosynthetic process|transport|cellular response to starvation|arachidonic acid metabolic process|long-chain fatty acid biosynthetic process|oxidation-reduction process|,"iron ion binding|linoleoyl-CoA desaturase activity|acyl-CoA desaturase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water|heme binding|",9,0.1,0.499,9,-0.1,0.0812,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000025779,LY96,lymphocyte antigen 96,extracellular region|lipopolysaccharide receptor complex|,pattern recognition receptor signaling pathway|immune system process|inflammatory response|lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signaling pathway|response to lipopolysaccharide|detection of lipopolysaccharide|innate immune response|,lipopolysaccharide receptor activity|protein binding|,10,0.1,0.123,10,0,0,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000022766,SERPIND1,"serine (or cysteine) peptidase inhibitor, clade D, member 1",extracellular space|extracellular vesicular exosome|,blood coagulation|hemostasis|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|heparin binding|peptidase inhibitor activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000025429,PSTPIP2,proline-serine-threonine phosphatase-interacting protein 2,cytoplasm|cytosol|cytoskeleton|membrane|,cytoskeleton organization|,actin binding|protein binding|,10,-0.2,0.642,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000044583,TLR7,toll-like receptor 7,cytoplasm|lysosome|endosome|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|early phagosome|receptor complex|,microglial cell activation|toll-like receptor signaling pathway|immune system process|MyD88-dependent toll-like receptor signaling pathway|inflammatory response|immune response|signal transduction|I-kappaB phosphorylation|positive regulation of chemokine production|positive regulation of interleukin-6 production|positive regulation of interleukin-8 production|toll-like receptor 7 signaling pathway|positive regulation of NF-kappaB import into nucleus|positive regulation of interferon-gamma biosynthetic process|innate immune response|positive regulation of interferon-alpha biosynthetic process|positive regulation of interferon-alpha biosynthetic process|positive regulation of interferon-beta biosynthetic process|positive regulation of interleukin-8 biosynthetic process|defense response to virus|defense response to virus|,double-stranded RNA binding|single-stranded RNA binding|transmembrane signaling receptor activity|protein binding|drug binding|siRNA binding|,9,-0.2,0.571,9,0,0,0,0,0,0.879,0,0,-1.7,1.3
ENSMUSG00000027577,CHRNA4,"cholinergic receptor, nicotinic, alpha polypeptide 4",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|acetylcholine-gated channel complex|external side of plasma membrane|membrane|membrane|integral component of membrane|cell junction|dendrite|neuronal cell body|synapse|postsynaptic membrane|,"action potential|response to hypoxia|DNA repair|transport|ion transport|cation transport|cation transport|calcium ion transport|response to oxidative stress|signal transduction|synaptic transmission, cholinergic|synaptic transmission, cholinergic|synaptic transmission, cholinergic|respiratory gaseous exchange|locomotory behavior|regulation of dopamine secretion|sensory perception of pain|sensory perception of pain|positive regulation of dopamine secretion|ion transmembrane transport|response to nicotine|response to nicotine|response to nicotine|behavioral response to nicotine|behavioral response to nicotine|exploration behavior|B cell activation|regulation of membrane potential|neurological system process|neurological system process|cognition|protein heterooligomerization|membrane depolarization|membrane depolarization|regulation of inhibitory postsynaptic membrane potential|",acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|drug binding|acetylcholine receptor activity|acetylcholine binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.1,1.9
ENSMUSG00000026251,CHRND,"cholinergic receptor, nicotinic, delta polypeptide",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,skeletal muscle contraction|transport|ion transport|cation transport|cation transport|ion transmembrane transport|ion transmembrane transport|regulation of membrane potential|skeletal muscle tissue growth|musculoskeletal movement|,acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|ligand-gated ion channel activity|acetylcholine binding|,10,0.1,0.228,10,0,0,0,0,0,0.879,0,0,-1.2,1.8
ENSMUSG00000071713,CSF2RB,"colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)",membrane|integral component of membrane|,cytokine-mediated signaling pathway|,cytokine receptor activity|protein binding|,9,0.1,0.0371,10,-0.2,1.19,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000049796,CRH,corticotropin releasing hormone,extracellular region|extracellular space|cytoplasm|neuronal cell body|varicosity|perikaryon|,"positive regulation of protein phosphorylation|synaptic transmission, dopaminergic|glucocorticoid biosynthetic process|inflammatory response|inflammatory response|female pregnancy|learning or memory|long-term memory|feeding behavior|positive regulation of cell proliferation|associative learning|hormone-mediated apoptotic signaling pathway|positive regulation of gene expression|negative regulation of gene expression|negative regulation of norepinephrine secretion|positive regulation of cell death|regulation of serotonin secretion|lung development|adrenal gland development|positive regulation of cAMP biosynthetic process|negative regulation of epinephrine secretion|negative regulation of luteinizing hormone secretion|locomotory exploration behavior|positive regulation of insulin secretion involved in cellular response to glucose stimulus|negative regulation of blood pressure|positive regulation of corticotropin secretion|positive regulation of cortisol secretion|long-term synaptic potentiation|positive regulation of digestive system process|negative regulation of cell death|negative regulation of glucagon secretion|cellular response to cocaine|positive regulation of calcium ion import|regulation of N-methyl-D-aspartate selective glutamate receptor activity|positive regulation of corticosterone secretion|positive regulation of behavioral fear response|",receptor binding|hormone activity|corticotropin-releasing hormone activity|corticotropin-releasing hormone receptor 1 binding|corticotropin-releasing hormone receptor 2 binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000052821,CYSLTR1,cysteinyl leukotriene receptor 1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,calcium ion transport|chemotaxis|inflammatory response|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of angiogenesis|positive regulation of vasoconstriction|,signal transducer activity|G-protein coupled receptor activity|leukotriene receptor activity|leukotriene receptor activity|,10,0,0,10,-0.3,0.883,0,0,0,0.879,0,0,-1.7,1.2
ENSMUSG00000031842,PDE4C,"phosphodiesterase 4C, cAMP specific",extracellular space|cilium|cell projection|primary cilium|,cAMP catabolic process|signal transduction|negative regulation of insulin secretion|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|phosphoric diester hydrolase activity|drug binding|hydrolase activity|metal ion binding|",10,-0.2,0.231,10,0.2,0.305,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000024158,HAGH,hydroxyacyl glutathione hydrolase,cytoplasm|mitochondrion|mitochondrial matrix|extracellular vesicular exosome|,carbohydrate metabolic process|glutathione metabolic process|glutathione biosynthetic process|glutathione biosynthetic process|,hydroxyacylglutathione hydrolase activity|hydroxyacylglutathione hydrolase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.3,0.166,0,0,0,0.879,0,0,-1.7,1.2
ENSMUSG00000020349,PPP2CA,"protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform","protein phosphatase type 2A complex|protein phosphatase type 2A complex|chromosome, centromeric region|nucleus|chromosome|cytoplasm|cytosol|cytoskeleton|plasma membrane|extracellular vesicular exosome|",regulation of protein phosphorylation|protein dephosphorylation|protein dephosphorylation|meiotic nuclear division|mesoderm development|regulation of receptor activity|negative regulation of epithelial to mesenchymal transition|regulation of protein autophosphorylation|regulation of protein catabolic process|regulation of cell cycle|protein heterotrimerization|positive regulation of protein serine/threonine kinase activity|,phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein serine/threonine phosphatase activity|protein binding|protein C-terminus binding|protein C-terminus binding|hydrolase activity|metal ion binding|protein dimerization activity|GABA receptor binding|,3,0,0,2,0,0,0,0,0,0.879,0,0,-1.7,2
ENSMUSG00000042429,ADORA1,adenosine A1 receptor,endoplasmic reticulum|plasma membrane|endomembrane system|postsynaptic density|membrane|integral component of membrane|basolateral plasma membrane|dendrite|axolemma|asymmetric synapse|presynaptic membrane|neuronal cell body|terminal bouton|cell body|postsynaptic membrane|presynaptic active zone|,"activation of MAPKK activity|temperature homeostasis|response to hypoxia|adenosine receptor signaling pathway|regulation of respiratory gaseous exchange by neurological system process|negative regulation of acute inflammatory response|negative regulation of leukocyte migration|positive regulation of peptide secretion|regulation of glomerular filtration|protein targeting to membrane|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|negative regulation of cell proliferation|negative regulation of glutamate secretion|lipid catabolic process|negative regulation of synaptic transmission, GABAergic|positive regulation of nucleoside transport|negative regulation of neurotrophin production|positive regulation of protein dephosphorylation|negative regulation of renal sodium excretion|negative regulation of circadian sleep/wake cycle, sleep|negative regulation of circadian sleep/wake cycle, non-REM sleep|negative regulation of apoptotic process|positive regulation of potassium ion transport|positive regulation of epidermal growth factor-activated receptor activity|negative regulation of blood pressure|positive regulation of blood pressure|negative regulation of heart contraction|negative regulation of vasodilation|negative regulation of hormone secretion|regulation of synaptic plasticity|negative regulation of inflammatory response|cognition|detection of temperature stimulus involved in sensory perception of pain|negative regulation of lipid catabolic process|regulation of sensory perception of pain|negative regulation of synaptic transmission, glutamatergic|regulation of cardiac muscle contraction|negative regulation of cardiac muscle contraction|regulation of excitatory postsynaptic membrane potential|regulation of excitatory postsynaptic membrane potential|relaxation of vascular smooth muscle|negative regulation of mucus secretion|",G-protein coupled adenosine receptor activity|G-protein coupled receptor binding|purine nucleoside binding|phospholipase C activity|signal transducer activity|G-protein coupled receptor activity|G-protein beta/gamma-subunit complex binding|heterotrimeric G-protein binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000055078,GABRA5,"gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5",plasma membrane|membrane|integral component of membrane|cell junction|dendrite|dendrite|neuronal cell body membrane|chloride channel complex|receptor complex|cell body|synapse|postsynaptic membrane|,behavioral fear response|transport|ion transport|chloride transport|signal transduction|gamma-aminobutyric acid signaling pathway|synaptic transmission|sensory perception of sound|associative learning|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|neuron development|inner ear receptor cell development|innervation|cochlea development|,GABA-A receptor activity|ion channel activity|extracellular ligand-gated ion channel activity|chloride channel activity|protein binding|GABA receptor binding|,9,0,0,9,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000026011,CTLA4,cytotoxic T-lymphocyte-associated protein 4,Golgi apparatus|plasma membrane|external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|clathrin-coated endocytic vesicle|perinuclear region of cytoplasm|,immune system process|immune response|cellular response to DNA damage stimulus|negative regulation of B cell proliferation|negative regulation of T cell proliferation|positive regulation of apoptotic process|negative regulation of regulatory T cell differentiation|negative regulation of immune response|B cell receptor signaling pathway|,None,10,0.4,1.52,10,-0.2,0.104,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000028876,EPHA10,Eph receptor A10,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|phosphorylation|peptidyl-tyrosine phosphorylation|ephrin receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|transmembrane-ephrin receptor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-1.9,0.922,10,-0.1,0.638,0,0,0,0.879,0,0,-3,0.7
ENSMUSG00000001751,NAGLU,alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB),extracellular vesicular exosome|,lysosome organization|metabolic process|cerebellar Purkinje cell layer development|middle ear morphogenesis|locomotor rhythm|retinal rod cell development|inner ear receptor cell development|,"alpha-N-acetylglucosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.3,0.677,10,-0.1,0.0604,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000023707,OGFOD2,2-oxoglutarate and iron-dependent oxygenase domain containing 2,cellular_component|,oxidation-reduction process|,"sulfonate dioxygenase activity|molecular_function|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|L-ascorbic acid binding|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0,0,10,-0.1,0.0295,0,0,0,0.879,0,0,-1.8,1.2
ENSMUSG00000028747,HTR6,5-hydroxytryptamine (serotonin) receptor 6,plasma membrane|cilium|membrane|integral component of membrane|dendrite|,"signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|serotonin receptor signaling pathway|learning|negative regulation of glutamate secretion|negative regulation of gamma-aminobutyric acid secretion|positive regulation of gamma-aminobutyric acid secretion|negative regulation of acetylcholine secretion, neurotransmission|positive regulation of dopamine secretion|long-term synaptic potentiation|",signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|,9,0,0,10,0,0,0,0,0,0.879,0,0,-1.7,1.5
ENSMUSG00000039431,MTMR7,myotubularin related protein 7,cytoplasm|cytosol|membrane|,dephosphorylation|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|,"protein tyrosine phosphatase activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000026409,PFKFB2,"6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2",cytoplasm|,"fructose metabolic process|fructose 2,6-bisphosphate metabolic process|glucose catabolic process|lactate metabolic process|pyruvate metabolic process|glycolytic process|metabolic process|response to glucose|phosphorylation|positive regulation of insulin secretion|positive regulation of glucokinase activity|carbohydrate phosphorylation|","nucleotide binding|catalytic activity|6-phosphofructo-2-kinase activity|fructose-2,6-bisphosphate 2-phosphatase activity|ATP binding|kinase activity|transferase activity|hydrolase activity|kinase binding|protein kinase binding|",10,0,0,10,0.7,1.9,0,0,0,0.879,0,0,-0.7,2
ENSMUSG00000038496,SLC19A3,"solute carrier family 19, member 3",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|drug transmembrane transport|thiamine transport|thiamine transmembrane transport|,thiamine transmembrane transporter activity|thiamine uptake transmembrane transporter activity|,9,0,0,9,0.3,0.0844,0,0,0,0.879,0,0,-1.2,1.8
ENSMUSG00000033276,STK36,serine/threonine kinase 36,nucleus|cytoplasm|cytoplasm|,epithelial cilium movement|protein phosphorylation|positive regulation of hh target transcription factor activity|multicellular organismal development|brain development|post-embryonic development|phosphorylation|cell projection organization|cilium assembly|positive regulation of smoothened signaling pathway|regulation of sequence-specific DNA binding transcription factor activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|transcription factor binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.5,1.46,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000001642,AKR1B3,"aldo-keto reductase family 1, member B3 (aldose reductase)",extracellular space|nucleus|cytoplasm|cytosol|cell projection cytoplasm|paranodal junction|mast cell granule|Schmidt-Lanterman incisure|perinuclear region of cytoplasm|extracellular vesicular exosome|Schwann cell microvillus|,tissue homeostasis|monosaccharide metabolic process|sorbitol biosynthetic process|response to water deprivation|response to organic substance|naphthalene metabolic process|stress-activated protein kinase signaling cascade|norepinephrine metabolic process|daunorubicin metabolic process|doxorubicin metabolic process|positive regulation of JAK-STAT cascade|positive regulation of smooth muscle cell proliferation|oxidation-reduction process|cellular response to hydrogen peroxide|inner medullary collecting duct development|cellular response to methylglyoxal|,alditol:NADP+ 1-oxidoreductase activity|alditol:NADP+ 1-oxidoreductase activity|oxidoreductase activity|glyceraldehyde oxidoreductase activity|,10,0,0,10,-0.1,0.276,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000002688,PRKD1,protein kinase D1,intracellular|cell|nucleus|cytoplasm|cytoplasm|Golgi apparatus|trans-Golgi network|trans-Golgi network|cytosol|plasma membrane|plasma membrane|cell-cell junction|cell cortex|membrane|,angiogenesis|positive regulation of endothelial cell proliferation|immune system process|protein phosphorylation|apoptotic process|inflammatory response|Golgi organization|nervous system development|positive regulation of endothelial cell migration|regulation of keratinocyte proliferation|positive regulation of neuron projection development|phosphorylation|peptidyl-serine phosphorylation|cell differentiation|positive regulation of CREB transcription factor activity|positive regulation of peptidyl-serine phosphorylation|cellular response to oxidative stress|intracellular signal transduction|cellular response to vascular endothelial growth factor stimulus|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of blood vessel endothelial cell migration|innate immune response|positive regulation of osteoblast differentiation|positive regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|vascular endothelial growth factor receptor signaling pathway|Golgi vesicle transport|positive regulation of NF-kappaB transcription factor activity|negative regulation of cell death|positive regulation of histone deacetylase activity|positive regulation of endothelial cell chemotaxis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|metal ion binding|",10,-0.2,0.744,10,0.1,0.191,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000066279,CHRNA10,"cholinergic receptor, nicotinic, alpha polypeptide 10",plasma membrane|acetylcholine-gated channel complex|membrane|integral component of membrane|cell junction|axon|perikaryon|synapse|postsynaptic membrane|,"transport|ion transport|cation transport|positive regulation of cytosolic calcium ion concentration|synaptic transmission, cholinergic|ion transmembrane transport|inner ear morphogenesis|detection of mechanical stimulus involved in sensory perception of sound|",acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|,10,0.1,0.044,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000005034,PRKACB,"protein kinase, cAMP dependent, catalytic, beta",nucleus|cytoplasm|centrosome|cytosol|plasma membrane|cAMP-dependent protein kinase complex|cAMP-dependent protein kinase complex|membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|ciliary base|,neural tube closure|protein phosphorylation|protein phosphorylation|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|phosphorylation|negative regulation of meiotic cell cycle|regulation of protein processing|negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|cAMP-dependent protein kinase activity|cAMP-dependent protein kinase activity|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|ubiquitin protein ligase binding|",9,-0.2,0.526,9,0,0,0,0,0,0.879,0,0,-1.8,1.3
ENSMUSG00000020918,KAT2A,K(lysine) acetyltransferase 2A,histone acetyltransferase complex|extracellular space|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|STAGA complex|STAGA complex|transcription factor TFTC complex|mitotic spindle|,"in utero embryonic development|somitogenesis|somitogenesis|neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|cell proliferation|histone acetylation|histone deubiquitination|telencephalon development|metencephalon development|midbrain development|regulation of protein stability|multicellular organism growth|positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter|histone H3 acetylation|histone H4-K12 acetylation|histone H3-K14 acetylation|regulation of RNA biosynthetic process|","chromatin binding|transcription coactivator activity|histone acetyltransferase activity|histone acetyltransferase activity|histone acetyltransferase activity|protein binding|N-acetyltransferase activity|H3 histone acetyltransferase activity|H3 histone acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|histone deacetylase binding|histone acetyltransferase activity (H4-K12 specific)|",9,0,0,9,0,0,0,0,0,0.879,0,0,-2,1.1
ENSMUSG00000053158,FES,feline sarcoma oncogene,cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|focal adhesion|microtubule cytoskeleton|membrane|cell junction|extrinsic component of cytoplasmic side of plasma membrane|cytoplasmic vesicle|,protein phosphorylation|regulation of cell shape|positive regulation of neuron projection development|phosphorylation|peptidyl-tyrosine phosphorylation|regulation of cell adhesion|positive regulation of microtubule polymerization|regulation of cell proliferation|regulation of mast cell degranulation|regulation of cell differentiation|positive regulation of myeloid cell differentiation|protein autophosphorylation|regulation of cell motility|positive regulation of actin cytoskeleton reorganization|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein binding|ATP binding|lipid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|immunoglobulin receptor binding|phosphatidylinositol binding|",10,-0.1,0.0948,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000042604,KCNA4,"potassium voltage-gated channel, shaker-related subfamily, member 4",integral component of plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|potassium ion binding|,10,0.5,1.69,10,0,0,0,0,0,0.879,0,0,-0.8,1.9
ENSMUSG00000035745,GRIN3B,"glutamate receptor, ionotropic, NMDA3B",plasma membrane|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|dendrite|neuronal cell body|neuronal cell body|synapse|postsynaptic membrane|,"transport|ion transport|cation transport|synaptic transmission|ion transmembrane transport|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|protein insertion into membrane|regulation of calcium ion transport|",receptor activity|ionotropic glutamate receptor activity|N-methyl-D-aspartate selective glutamate receptor activity|transporter activity|ion channel activity|extracellular-glutamate-gated ion channel activity|cation channel activity|calcium channel activity|glycine binding|neurotransmitter receptor activity|neurotransmitter binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000073421,H2-AB1,"histocompatibility 2, class II antigen A, beta 1",intracellular|early endosome|multivesicular body|Golgi apparatus|plasma membrane|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|MHC class II protein complex|,B cell affinity maturation|immune system process|immunoglobulin production involved in immunoglobulin mediated immune response|humoral immune response mediated by circulating immunoglobulin|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|positive regulation of antigen processing and presentation|positive regulation of T-helper 1 type immune response|immune response|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|negative regulation of T cell proliferation|positive regulation of alpha-beta T cell activation|positive regulation of alpha-beta T cell activation|positive regulation of alpha-beta T cell activation|antigen processing and presentation of peptide antigen|cellular response to interferon-gamma|,protein binding|transcription factor binding|toxic substance binding|ubiquitin protein ligase binding|peptide antigen binding|protein heterodimerization activity|repressing transcription factor binding|,10,-0.1,0.169,10,0.1,0.317,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000074768,BHMT,betaine-homocysteine methyltransferase,cytoplasm|cytosol|protein complex|extracellular vesicular exosome|,protein methylation|amino-acid betaine metabolic process|methionine biosynthetic process|methionine biosynthetic process|methylation|S-methylmethionine metabolic process|L-methionine salvage|,methyltransferase activity|zinc ion binding|S-adenosylmethionine-homocysteine S-methyltransferase activity|protein complex binding|betaine-homocysteine S-methyltransferase activity|S-methylmethionine-homocysteine S-methyltransferase activity|,10,0.1,0.123,10,0,0,0,0,0,0.879,0,0,-1.7,1.3
ENSMUSG00000032769,TRPA1,"transient receptor potential cation channel, subfamily A, member 1",membrane|integral component of membrane|stereocilium bundle|,transport|ion transport|calcium ion transport|calcium ion transport|response to cold|response to cold|response to drug|response to hydrogen peroxide|response to pain|response to pain|response to stimulus|thermoception|detection of mechanical stimulus involved in sensory perception of pain|detection of chemical stimulus involved in sensory perception of pain|detection of chemical stimulus involved in sensory perception of pain|calcium ion transmembrane transport|,ion channel activity|ion channel activity|calcium channel activity|calcium channel activity|channel activity|,10,0,0,10,-0.2,0.411,0,0,0,0.879,0,0,-1.8,1.1
ENSMUSG00000042808,GPX2,glutathione peroxidase 2,cytoplasm|cytosol|extracellular vesicular exosome|,temperature homeostasis|negative regulation of inflammatory response to antigenic stimulus|response to oxidative stress|response to symbiotic bacterium|interaction with symbiont|oxidation-reduction process|,peroxidase activity|glutathione peroxidase activity|glutathione peroxidase activity|glutathione peroxidase activity|oxidoreductase activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000025094,SLC18A2,"solute carrier family 18 (vesicular monoamine), member 2",cytoplasm|synaptic vesicle|membrane|integral component of membrane|synaptic vesicle membrane|dense core granule|cytoplasmic vesicle|cell projection|neuron projection|neuronal cell body|terminal bouton|axon terminus|cell body|,response to amphetamine|transport|neurotransmitter transport|serotonin transport|aging|locomotory behavior|response to toxic substance|post-embryonic development|synaptic vesicle amine transport|monoamine transport|drug transport|death|insulin secretion|ion transmembrane transport|cellular response to drug|glucose homeostasis|negative regulation of neurotransmitter transport|transmembrane transport|,amine transmembrane transporter activity|protein binding|drug binding|serotonin transmembrane transporter activity|drug transmembrane transporter activity|enzyme binding|heat shock protein binding|,10,0,0,10,-0.1,0.0921,0,0,0,0.879,0,0,-1.9,1.1
ENSMUSG00000033831,FGB,fibrinogen beta chain,extracellular region|fibrinogen complex|extracellular space|cytoplasm|cell cortex|external side of plasma membrane|cell surface|platelet alpha granule|extracellular vesicular exosome|blood microparticle|,cell-matrix adhesion|signal transduction|blood coagulation|hemostasis|platelet activation|positive regulation of heterotypic cell-cell adhesion|cellular protein complex assembly|positive regulation of vasoconstriction|positive regulation of exocytosis|positive regulation of protein secretion|protein polymerization|response to calcium ion|positive regulation of ERK1 and ERK2 cascade|platelet aggregation|positive regulation of peptide hormone secretion|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of endothelial cell apoptotic process|,"receptor binding|structural molecule activity|protein binding, bridging|cell adhesion molecule binding|chaperone binding|",10,0,0,10,-0.1,0.0315,0,0,0,0.879,0,0,-1.8,1.1
ENSMUSG00000053460,GGCX,gamma-glutamyl carboxylase,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,peptidyl-glutamic acid carboxylation|,gamma-glutamyl carboxylase activity|gamma-glutamyl carboxylase activity|lyase activity|vitamin binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000030522,MTMR10,myotubularin related protein 10,cellular_component|,dephosphorylation|,phosphatase activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000022180,SLC7A8,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 8",cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,amino acid transmembrane transport|transport|amino acid transport|amino acid transport|organic cation transport|L-amino acid transport|amine transport|transmembrane transport|toxin transport|L-alpha-amino acid transmembrane transport|,amine transmembrane transporter activity|organic cation transmembrane transporter activity|amino acid transmembrane transporter activity|L-amino acid transmembrane transporter activity|toxin transporter activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.7,1.3
ENSMUSG00000020882,CACNB1,"calcium channel, voltage-dependent, beta 1 subunit",intracellular|cell|plasma membrane|voltage-gated calcium channel complex|membrane|sarcoplasmic reticulum|T-tubule|,protein targeting to membrane|transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|high voltage-gated calcium channel activity|,9,0,0,9,0,0,0,0,0,0.879,0,0,-1.9,1.2
ENSMUSG00000053693,MAST1,microtubule associated serine/threonine kinase 1,cytoplasm|cytoskeleton|plasma membrane|membrane|,protein phosphorylation|cytoskeleton organization|phosphorylation|intracellular signal transduction|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",7,0,0,7,0.3,0.594,0,0,0,0.879,0,0,-1.2,2
ENSMUSG00000049152,UGT3A2,"UDP glycosyltransferases 3 family, polypeptide A2",cellular_component|membrane|integral component of membrane|,metabolic process|cellular response to genistein|,"UDP-glycosyltransferase activity|UDP-glycosyltransferase activity|glucuronosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000025495,PTDSS2,phosphatidylserine synthase 2,intracellular|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,lipid metabolic process|phosphatidylserine biosynthetic process|phospholipid biosynthetic process|,CDP-diacylglycerol-serine O-phosphatidyltransferase activity|transferase activity|,10,0,0,10,-0.2,0.586,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000053773,RDH8,retinol dehydrogenase 8,None,visual perception|retinol metabolic process|oxidation-reduction process|,retinol dehydrogenase activity|,9,0.4,1.19,9,0,0,0,0,0,0.879,0,0,-0.8,2
ENSMUSG00000025199,CHUK,conserved helix-loop-helix ubiquitous kinase,nucleus|cytoplasm|cytoplasm|cytosol|IkappaB kinase complex|cytoplasmic side of plasma membrane|CD40 receptor complex|intracellular membrane-bounded organelle|,morphogenesis of an epithelial sheet|protein phosphorylation|protein phosphorylation|I-kappaB phosphorylation|I-kappaB phosphorylation|Rho protein signal transduction|lactation|lactation|response to organic substance|phosphorylation|signal transduction by phosphorylation|osteoclast differentiation|osteoclast differentiation|response to lipopolysaccharide|mammary gland epithelial cell proliferation|mammary gland epithelial cell proliferation|odontogenesis of dentin-containing tooth|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of transcription from RNA polymerase II promoter|striated muscle cell differentiation|mammary gland alveolus development|mammary gland alveolus development|cellular response to tumor necrosis factor|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity|protein binding|ATP binding|IkappaB kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|protein heterodimerization activity|scaffold protein binding|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.4,1.7
ENSMUSG00000053093,MYH7,"myosin, heavy polypeptide 7, cardiac muscle, beta",stress fiber|nucleus|cytoplasm|muscle myosin complex|focal adhesion|myosin complex|myofibril|Z disc|myosin filament|,regulation of the force of heart contraction|regulation of heart rate|ATP catabolic process|muscle contraction|striated muscle contraction|adult heart development|muscle filament sliding|ventricular cardiac muscle tissue morphogenesis|,microfilament motor activity|nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|ATPase activity|actin-dependent ATPase activity|protein homodimerization activity|protein heterodimerization activity|,10,-1,1.67,10,0.2,0.284,0,0,0,0.879,0,0,-2,0.8
ENSMUSG00000028517,PPAP2B,phosphatidic acid phosphatase type 2B,endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,blood vessel development|gastrulation with mouth forming second|negative regulation of protein phosphorylation|negative regulation of protein phosphorylation|phospholipid metabolic process|cell adhesion|multicellular organismal development|dephosphorylation|single organismal cell-cell adhesion|regulation of Wnt signaling pathway|homotypic cell-cell adhesion|canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration|canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt signaling pathway involved in positive regulation of wound healing|positive regulation of peptidyl-tyrosine phosphorylation|protein stabilization|protein stabilization|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|Bergmann glial cell differentiation|canonical Wnt signaling pathway|regulation of sphingolipid mediated signaling pathway|,catalytic activity|integrin binding|phosphatidate phosphatase activity|hydrolase activity|sphingosine-1-phosphate phosphatase activity|lipid phosphatase activity|,9,-0.2,0.721,9,0,0,0,0,0,0.879,0,0,-2,1
ENSMUSG00000030525,CHRNA7,"cholinergic receptor, nicotinic, alpha polypeptide 7",cytoplasm|plasma membrane|acetylcholine-gated channel complex|external side of plasma membrane|postsynaptic density|membrane|integral component of membrane|apical plasma membrane|cell junction|axon|dendrite|growth cone|asymmetric synapse|presynaptic membrane|neuronal cell body|dendritic spine|dendritic shaft|membrane raft|synapse|postsynaptic membrane|,"activation of MAPK activity|response to hypoxia|positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure|transport|ion transport|cation transport|calcium ion transport|cellular calcium ion homeostasis|endocytosis|signal transduction|synaptic transmission, cholinergic|synaptic transmission, cholinergic|memory|positive regulation of cell proliferation|associative learning|associative learning|regulation of norepinephrine secretion|neuronal action potential|sperm motility|response to food|regulation of synaptic transmission, dopaminergic|negative regulation of interleukin-1 beta production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|negative regulation of tumor necrosis factor production|ion transmembrane transport|ion transmembrane transport|response to nicotine|response to nicotine|behavioral response to nicotine|T cell activation|B cell activation|regulation of membrane potential|regulation of membrane potential|ovulation cycle|response to ethanol|positive regulation of angiogenesis|behavioral response to ethanol|regulation of inflammatory response|negative regulation of inflammatory response|cognition|generation of ovulation cycle rhythm|",beta-amyloid binding|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|drug binding|adenylate cyclase binding|acetylcholine receptor activity|toxic substance binding|chloride channel regulator activity|protein kinase binding|acetylcholine-gated cation channel activity|acetylcholine binding|protein homodimerization activity|ATPase binding|scaffold protein binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000019235,RPS6KL1,ribosomal protein S6 kinase-like 1,cellular_component|ribosome|ribonucleoprotein complex|,protein phosphorylation|biological_process|phosphorylation|,"nucleotide binding|molecular_function|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000020267,HINT1,histidine triad nucleotide binding protein 1,histone deacetylase complex|nucleus|nucleus|cytoplasm|plasma membrane|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|purine ribonucleotide catabolic process|intrinsic apoptotic signaling pathway by p53 class mediator|",nucleotide binding|catalytic activity|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000023267,GABRR2,"gamma-aminobutyric acid (GABA) C receptor, subunit rho 2",plasma membrane|membrane|integral component of membrane|cell junction|axon|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|signal transduction|gamma-aminobutyric acid signaling pathway|visual perception|,GABA-A receptor activity|GABA-A receptor activity|extracellular ligand-gated ion channel activity|chloride channel activity|protein domain specific binding|,10,0.3,1.26,10,0,0,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000024242,MAP4K3,mitogen-activated protein kinase kinase kinase kinase 3,intracellular|,MAPK cascade|activation of MAPKKK activity|protein phosphorylation|protein phosphorylation|response to UV|phosphorylation|response to tumor necrosis factor|intracellular signal transduction|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.879,0,0,-0.9,2
ENSMUSG00000038128,CAMK4,calcium/calmodulin-dependent protein kinase IV,nucleus|nucleus|cytoplasm|extracellular vesicular exosome|,"immune system process|protein phosphorylation|protein phosphorylation|protein phosphorylation|protein phosphorylation|nucleocytoplasmic transport|inflammatory response|signal transduction|neuron-neuron synaptic transmission|long-term memory|phosphorylation|myeloid dendritic cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of protein export from nucleus|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|calmodulin-dependent protein kinase activity|protein binding|calmodulin binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.0322,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000020912,KRT12,keratin 12,intermediate filament|extracellular vesicular exosome|,epithelium development|cornea development in camera-type eye|,structural molecule activity|,10,0.3,1.12,10,0,0,0,0,0,0.879,0,0,-1,1.8
ENSMUSG00000036078,SIGMAR1,sigma non-opioid intracellular receptor 1,nucleus|nuclear envelope|endoplasmic reticulum|lipid particle|plasma membrane|membrane|integral component of membrane|cell junction|cell projection|,transport|lipid transport|nervous system development|opioid receptor signaling pathway|regulation of neuron apoptotic process|,receptor activity|opioid receptor activity|protein binding|,10,0.1,0.27,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000030674,QPRT,quinolinate phosphoribosyltransferase,cytoplasm|extracellular vesicular exosome|,NAD biosynthetic process|pyridine nucleotide biosynthetic process|quinolinate catabolic process|quinolinate metabolic process|protein oligomerization|,"catalytic activity|nicotinate-nucleotide diphosphorylase (carboxylating) activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring pentosyl groups|protein homodimerization activity|",10,0.3,0.616,10,-0.1,0.157,0,0,0,0.879,0,0,-1.2,1.6
ENSMUSG00000090071,CDK5R2,"cyclin-dependent kinase 5, regulatory subunit 2 (p39)",cytoplasm|plasma membrane|membrane|cyclin-dependent protein kinase 5 holoenzyme complex|,neuron migration|cerebellum development|superior olivary nucleus maturation|hippocampus development|layer formation in cerebral cortex|positive regulation of protein kinase activity|positive regulation of calcium ion-dependent exocytosis|positive regulation of protein serine/threonine kinase activity|,cytoskeletal protein binding|lipid binding|cyclin-dependent protein kinase 5 activator activity|cyclin-dependent protein kinase 5 activator activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000031390,AVPR2,arginine vasopressin receptor 2,intracellular|plasma membrane|membrane|integral component of membrane|,positive regulation of systemic arterial blood pressure|signal transduction|G-protein coupled receptor signaling pathway|I-kappaB kinase/NF-kappaB signaling|positive regulation of cell proliferation|positive regulation of gene expression|interferon-gamma production|response to cytokine|negative regulation of urine volume|negative regulation of renal sodium excretion|positive regulation of blood pressure|,signal transducer activity|G-protein coupled receptor activity|vasopressin receptor activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.8,1.1
ENSMUSG00000019843,FYN,Fyn proto-oncogene,nucleus|cytoplasm|mitochondrion|endosome|plasma membrane|postsynaptic density|membrane|intracellular membrane-bounded organelle|membrane raft|,neuron migration|neuron migration|immune system process|protein phosphorylation|cell surface receptor signaling pathway|multicellular organismal development|regulation of cell shape|negative regulation of gene expression|positive regulation of neuron projection development|positive regulation of phosphatidylinositol 3-kinase signaling|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|forebrain development|forebrain development|negative regulation of protein catabolic process|myelination|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of neuron apoptotic process|response to ethanol|protein autophosphorylation|protein autophosphorylation|dendrite morphogenesis|activated T cell proliferation|T cell receptor signaling pathway|detection of mechanical stimulus involved in sensory perception of pain|positive regulation of protein localization to nucleus|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,"nucleotide binding|G-protein coupled receptor binding|glycoprotein binding|protein kinase activity|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|receptor binding|protein binding|ATP binding|tubulin binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein complex binding|T cell receptor binding|CD4 receptor binding|CD8 receptor binding|phosphatidylinositol 3-kinase binding|ion channel binding|metal ion binding|ephrin receptor binding|peptide hormone receptor binding|growth factor receptor binding|",10,0.1,0.19,10,0,0,0,0,0,0.879,0,0,-1.4,1.5
ENSMUSG00000024782,AK3,adenylate kinase 3,mitochondrion|mitochondrial intermembrane space|mitochondrial matrix|mitochondrial matrix|,nucleobase-containing compound metabolic process|ADP biosynthetic process|AMP phosphorylation|phosphorylation|AMP metabolic process|ATP metabolic process|GTP metabolic process|ITP metabolic process|UTP metabolic process|dATP metabolic process|nucleotide phosphorylation|nucleotide phosphorylation|protein homooligomerization|,"nucleotide binding|adenylate kinase activity|adenylate kinase activity|ATP binding|GTP binding|kinase activity|transferase activity|phosphotransferase activity, phosphate group as acceptor|nucleobase-containing compound kinase activity|identical protein binding|nucleoside triphosphate adenylate kinase activity|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000032322,PSTPIP1,proline-serine-threonine phosphatase-interacting protein 1,stress fiber|cytoplasm|actomyosin contractile ring|cytoskeleton|membrane|cleavage furrow|cell projection|,cytokinesis|immune system process|endocytosis|inflammatory response|cell adhesion|innate immune response|,actin binding|protein binding|protein phosphatase binding|,10,-0.2,0.261,10,0,0,0,0,0,0.879,0,0,-1.8,1.2
ENSMUSG00000022620,ARSA,arylsulfatase A,acrosomal vesicle|extracellular space|cytoplasm|lysosome|endosome|plasma membrane|integral component of membrane|extrinsic component of external side of plasma membrane|extracellular vesicular exosome|,autophagy|binding of sperm to zona pellucida|central nervous system development|response to nutrient|metabolic process|response to pH|response to estrogen|response to ethanol|response to methylmercury|,catalytic activity|arylsulfatase activity|cerebroside-sulfatase activity|calcium ion binding|sulfuric ester hydrolase activity|hydrolase activity|metal ion binding|,9,-0.2,0.501,9,0.1,0.0562,0,0,0,0.879,0,0,-1.9,1.1
ENSMUSG00000026723,TRDMT1,tRNA aspartic acid methyltransferase 1,nucleus|cytoplasm|,DNA methylation|tRNA processing|tRNA methylation|tRNA methylation|methylation|,DNA binding|RNA binding|methyltransferase activity|tRNA methyltransferase activity|tRNA methyltransferase activity|transferase activity|,9,0,0,9,-0.2,0.957,0,0,0,0.879,0,0,-1.8,1.3
ENSMUSG00000032496,LTF,lactotransferrin,extracellular region|extracellular space|nucleus|cytoplasm|secretory granule|specific granule|extracellular vesicular exosome|,ossification|regulation of cytokine production|innate immune response in mucosa|immune system process|proteolysis|transport|ion transport|iron ion transport|cellular iron ion homeostasis|antibacterial humoral response|antifungal humoral response|negative regulation of lipopolysaccharide-mediated signaling pathway|regulation of tumor necrosis factor production|positive regulation of osteoblast proliferation|positive regulation of toll-like receptor 4 signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of osteoblast differentiation|positive regulation of NF-kappaB transcription factor activity|iron ion homeostasis|bone morphogenesis|positive regulation of protein serine/threonine kinase activity|negative regulation of single-species biofilm formation in or on host organism|positive regulation of chondrocyte proliferation|,iron ion binding|ferric iron binding|heparin binding|peptidase activity|serine-type peptidase activity|hydrolase activity|protein serine/threonine kinase activator activity|metal ion binding|,9,0,0,9,-0.4,1.57,0,0,0,0.879,0,0,-1.9,0.9
ENSMUSG00000026307,SCLY,selenocysteine lyase,cytoplasm|,selenium compound metabolic process|lipid metabolic process|metabolic process|response to insulin|negative regulation of cellular response to oxidative stress|,catalytic activity|selenocysteine lyase activity|transferase activity|lyase activity|pyridoxal phosphate binding|,10,0.1,0.0111,10,0,0,0,0,0,0.879,0,0,-1,2
ENSMUSG00000043153,ISPD,isoprenoid synthase domain containing,cellular_component|,protein glycosylation|axon guidance|isoprenoid biosynthetic process|protein O-linked mannosylation|,"telomerase activity|RNA helicase activity|catalytic activity|DNA primase activity|sulfate adenylyltransferase activity|RNA guanylyltransferase activity|tRNA guanylyltransferase activity|mannose-phosphate guanylyltransferase activity|transferase activity|nucleotidyltransferase activity|DNA/RNA helicase activity|CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity|phospholactate guanylyltransferase activity|ATP:coenzyme F420 adenylyltransferase activity|UDP-N-acetylgalactosamine diphosphorylase activity|",8,0,0,8,0.2,0.534,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000027513,PCK1,"phosphoenolpyruvate carboxykinase 1, cytosolic",cytoplasm|extracellular vesicular exosome|,glucose metabolic process|gluconeogenesis|gluconeogenesis|oxaloacetate metabolic process|internal protein amino acid acetylation|lipid metabolic process|phosphorylation|response to insulin|glucose homeostasis|glycerol biosynthetic process from pyruvate|glycerol biosynthetic process from pyruvate|,nucleotide binding|magnesium ion binding|phosphoenolpyruvate carboxykinase activity|phosphoenolpyruvate carboxykinase activity|phosphoenolpyruvate carboxykinase (GTP) activity|GTP binding|kinase activity|transferase activity|lyase activity|carboxy-lyase activity|purine nucleotide binding|GDP binding|manganese ion binding|carboxylic acid binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.2,1.8
ENSMUSG00000021647,CARTPT,CART prepropeptide,extracellular region|extracellular space|extracellular space|secretory granule|,activation of MAPKK activity|activation of MAPKK activity|cellular glucose homeostasis|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|adult feeding behavior|adult feeding behavior|cellular response to starvation|cellular response to starvation|negative regulation of appetite|negative regulation of appetite|positive regulation of epinephrine secretion|circadian regulation of gene expression|negative regulation of osteoclast differentiation|positive regulation of blood pressure|negative regulation of bone resorption|negative regulation of bone resorption|regulation of bone remodeling|regulation of insulin secretion|positive regulation of transmission of nerve impulse|negative regulation of glucagon secretion|somatostatin secretion|,neuropeptide hormone activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000025076,CASP7,caspase 7,nucleus|cytoplasm|cytosol|intracellular membrane-bounded organelle|,release of cytochrome c from mitochondria|proteolysis|proteolysis|proteolysis|apoptotic process|heart development|response to UV|protein processing|positive regulation of neuron apoptotic process|execution phase of apoptosis|,aspartic-type endopeptidase activity|cysteine-type endopeptidase activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|cysteine-type endopeptidase activity involved in apoptotic process|,9,-0.1,0.366,9,0.3,0.676,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000028980,H6PD,hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase),cytoplasm|mitochondrion|endoplasmic reticulum|intracellular membrane-bounded organelle|,carbohydrate metabolic process|glucose metabolic process|pentose-phosphate shunt|NADP metabolic process|metabolic process|oxidation-reduction process|,catalytic activity|glucose-6-phosphate dehydrogenase activity|glucose-6-phosphate dehydrogenase activity|oxidoreductase activity|hydrolase activity|6-phosphogluconolactonase activity|carbohydrate binding|glucose 1-dehydrogenase [NAD(P)] activity|NADP binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000025035,ARL3,ADP-ribosylation factor-like 3,intracellular|cell|nucleus|cytoplasm|Golgi apparatus|centrosome|cytoskeleton|spindle microtubule|cytoplasmic microtubule|cilium|membrane|midbody|photoreceptor connecting cilium|cell projection|extracellular vesicular exosome|primary cilium|,cytokinesis|kidney development|GTP catabolic process|transport|post-Golgi vesicle-mediated transport|cell cycle|smoothened signaling pathway|small GTPase mediated signal transduction|protein transport|intraciliary transport|photoreceptor cell development|cell division|cilium morphogenesis|,nucleotide binding|GTPase activity|protein binding|GTP binding|GTP binding|microtubule binding|GDP binding|GDP binding|metal ion binding|,10,0,0,9,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000025579,GAA,"glucosidase, alpha, acid",lysosome|lysosome|lysosome|lysosomal membrane|membrane|membrane|extracellular vesicular exosome|,regulation of the force of heart contraction|diaphragm contraction|diaphragm contraction|heart morphogenesis|carbohydrate metabolic process|glycogen metabolic process|glycogen catabolic process|glycogen catabolic process|striated muscle contraction|lysosome organization|lysosome organization|locomotory behavior|metabolic process|tissue development|vacuolar sequestering|muscle cell cellular homeostasis|neuromuscular process controlling posture|neuromuscular process controlling balance|cardiac muscle contraction|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-glucosidase activity|alpha-glucosidase activity|alpha-glucosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|maltose alpha-glucosidase activity|",10,0,0,10,0.1,0.0875,0,0,0,0.879,0,0,-1.2,1.8
ENSMUSG00000022241,TARS,threonyl-tRNA synthetase,cytoplasm|actin cytoskeleton|extracellular vesicular exosome|,translation|tRNA aminoacylation for protein translation|threonyl-tRNA aminoacylation|tRNA aminoacylation|,"nucleotide binding|aminoacyl-tRNA ligase activity|threonine-tRNA ligase activity|ATP binding|ligase activity|ligase activity, forming aminoacyl-tRNA and related compounds|",8,0,0,9,0,0,0,0,0,0.879,0,0,-2,1.1
ENSMUSG00000006445,EPHA2,Eph receptor A2,intracellular|plasma membrane|integral component of plasma membrane|focal adhesion|membrane|integral component of membrane|cell junction|leading edge membrane|cell projection|,skeletal system development|angiogenesis|blood vessel development|vasculogenesis|osteoblast differentiation|protein phosphorylation|apoptotic process|cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|intrinsic apoptotic signaling pathway in response to DNA damage|regulation of lamellipodium assembly|notochord formation|notochord formation|phosphorylation|cell migration|peptidyl-tyrosine phosphorylation|neural tube development|cell differentiation|neuron differentiation|neuron differentiation|keratinocyte differentiation|osteoclast differentiation|activation of Rac GTPase activity|mammary gland epithelial cell proliferation|regulation of cell adhesion mediated by integrin|post-anal tail morphogenesis|protein kinase B signaling|regulation of blood vessel endothelial cell migration|regulation of angiogenesis|bone remodeling|ephrin receptor signaling pathway|ephrin receptor signaling pathway|ephrin receptor signaling pathway|axial mesoderm formation|notochord morphogenesis|negative regulation of protein kinase B signaling|notochord cell development|cell chemotaxis|branching involved in mammary gland duct morphogenesis|lens fiber cell morphogenesis|regulation of ERK1 and ERK2 cascade|response to growth factor|positive regulation of establishment of protein localization to plasma membrane|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.7,0.98,0,0,0,0.879,0,0,-0.8,2
ENSMUSG00000032899,STYK1,serine/threonine/tyrosine kinase 1,plasma membrane|membrane|integral component of membrane|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000031698,MYLK3,myosin light chain kinase 3,cytoplasm|cytosol|actin cytoskeleton|,regulation of vascular permeability involved in acute inflammatory response|protein phosphorylation|protein phosphorylation|phosphorylation|sarcomere organization|sarcomere organization|sarcomerogenesis|cardiac myofibril assembly|positive regulation of sarcomere organization|cellular response to interleukin-1|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|calmodulin-dependent protein kinase activity|myosin light chain kinase activity|myosin light chain kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.112,10,0,0,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000028004,NPY2R,neuropeptide Y receptor Y2,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|nonmotile primary cilium|,"behavioral fear response|positive regulation of peptide secretion|outflow tract morphogenesis|cardiac left ventricle morphogenesis|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|nitric oxide mediated signal transduction|synaptic transmission|negative regulation of cAMP biosynthetic process|negative regulation of neurological system process|positive regulation of dopamine secretion|positive regulation of cell adhesion|positive regulation of smooth muscle contraction|positive regulation of circadian sleep/wake cycle, non-REM sleep|secretion|negative regulation of synaptic transmission|negative regulation of secretion|regulation of sensory perception of pain|negative regulation of synaptic transmission, glutamatergic|negative regulation of excitatory postsynaptic membrane potential|negative regulation of feeding behavior|",peptide YY receptor activity|peptide YY receptor activity|signal transducer activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|neuropeptide Y receptor activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000035828,PIM3,proviral integration site 3,cytoplasm|,protein phosphorylation|apoptotic process|cell cycle|regulation of mitotic cell cycle|phosphorylation|histone phosphorylation|negative regulation of apoptotic process|protein autophosphorylation|negative regulation of insulin secretion involved in cellular response to glucose stimulus|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-1,2.52,0,0,0,0.879,0,0,-2,0.5
ENSMUSG00000042118,BHMT2,betaine-homocysteine methyltransferase 2,cytoplasm|extracellular vesicular exosome|,methionine biosynthetic process|methylation|S-methylmethionine metabolic process|S-adenosylmethionine metabolic process|L-methionine salvage|,methyltransferase activity|zinc ion binding|S-adenosylmethionine-homocysteine S-methyltransferase activity|transferase activity|metal ion binding|betaine-homocysteine S-methyltransferase activity|S-methylmethionine-homocysteine S-methyltransferase activity|,10,-0.1,0.156,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000040495,CHRM4,"cholinergic receptor, muscarinic 4",cytoplasm|plasma membrane|integral component of plasma membrane|postsynaptic density|membrane|membrane|integral component of membrane|cell junction|asymmetric synapse|sarcolemma|neuronal cell body|axon terminus|synapse|postsynaptic membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway|synaptic transmission|regulation of locomotion|positive regulation of GTPase activity|,signal transducer activity|G-protein coupled receptor activity|guanyl-nucleotide exchange factor activity|G-protein coupled acetylcholine receptor activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000052504,EPHA3,Eph receptor A3,extracellular region|early endosome|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,endocardial cushion development|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|regulation of epithelial to mesenchymal transition|positive regulation of neuron projection development|phosphorylation|cell migration|peptidyl-tyrosine phosphorylation|regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|ephrin receptor signaling pathway|ephrin receptor signaling pathway|regulation of focal adhesion assembly|regulation of microtubule cytoskeleton organization|cellular response to retinoic acid|fasciculation of sensory neuron axon|fasciculation of motor neuron axon|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|GPI-linked ephrin receptor activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000032501,TRIB1,tribbles homolog 1 (Drosophila),nucleus|cytoplasm|,negative regulation of protein kinase activity|JNK cascade|negative regulation of smooth muscle cell migration|negative regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|response to lipopolysaccharide|response to lipopolysaccharide|regulation of MAP kinase activity|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of smooth muscle cell proliferation|regulation of catalytic activity|positive regulation of ubiquitin-protein transferase activity|,"protein kinase inhibitor activity|transcription factor binding|transcription factor binding|transcription factor binding|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase binding|ubiquitin protein ligase binding|ubiquitin-protein transferase regulator activity|",10,-0.1,0.0508,10,0.2,0.711,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000027556,CAR1,carbonic anhydrase 1,cytoplasm|extracellular vesicular exosome|,one-carbon metabolic process|,carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,0.1,0.239,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000022210,DHRS4,dehydrogenase/reductase (SDR family) member 4,nucleus|mitochondrion|peroxisome|peroxisome|peroxisomal membrane|nuclear membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,alcohol metabolic process|metabolic process|steroid metabolic process|cellular ketone metabolic process|retinal metabolic process|protein tetramerization|oxidation-reduction process|oxidation-reduction process|,"3-keto sterol reductase activity|retinal dehydrogenase activity|carbonyl reductase (NADPH) activity|receptor binding|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor|alcohol dehydrogenase [NAD(P)+] activity|",10,0.1,0.442,10,-0.1,0.0754,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000073174,MAGI2,"membrane associated guanylate kinase, WW and PDZ domain containing 2",nucleus|cytoplasm|cytoplasm|endosome|late endosome|plasma membrane|plasma membrane|tight junction|postsynaptic density|membrane|cell junction|dendrite|slit diaphragm|neuron projection|protein complex|synapse|perinuclear region of cytoplasm|,positive regulation of receptor internalization|signal transduction|nervous system development|negative regulation of cell proliferation|positive regulation of neuron projection development|cytoplasmic transport|negative regulation of cell migration|positive regulation of phosphoprotein phosphatase activity|negative regulation of activin receptor signaling pathway|nerve growth factor signaling pathway|receptor clustering|protein heterooligomerization|negative regulation of protein kinase B signaling|SMAD protein signal transduction|mitotic cell cycle arrest|cellular response to nerve growth factor stimulus|,signal transducer activity|protein binding|phosphatase binding|receptor signaling complex scaffold activity|receptor signaling complex scaffold activity|PDZ domain binding|beta-1 adrenergic receptor binding|protein complex binding|SMAD binding|type II activin receptor binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000024768,LIPF,"lipase, gastric",extracellular region|,lipid metabolic process|lipid catabolic process|oxidation-reduction process|,"triglyceride lipase activity|hydrolase activity|hydrolase activity, acting on ester bonds|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000028641,LEPRE1,leprecan 1,extracellular region|proteinaceous extracellular matrix|basement membrane|nucleus|cytoplasm|endoplasmic reticulum|plasma membrane|membrane|extracellular vesicular exosome|,protein folding|cell growth|protein hydroxylation|peptidyl-proline hydroxylation|collagen fibril organization|regulation of ossification|collagen metabolic process|regulation of protein secretion|protein stabilization|oxidation-reduction process|bone development|negative regulation of post-translational protein modification|,"iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|procollagen-proline 3-dioxygenase activity|L-ascorbic acid binding|metal ion binding|dioxygenase activity|",10,0.1,0.373,10,-0.1,0.556,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000036251,TRPM8,"transient receptor potential cation channel, subfamily M, member 8",plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|cellular calcium ion homeostasis|response to temperature stimulus|response to cold|response to cold|response to cold|ion transmembrane transport|response to stimulus|thermoception|thermoception|protein homotetramerization|transmembrane transport|protein homotrimerization|calcium ion transmembrane transport|,ion channel activity|ion channel activity|calcium channel activity|calcium channel activity|protein homodimerization activity|,10,-0.1,0.245,10,0,0,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000026778,PRKCQ,"protein kinase C, theta",immunological synapse|intracellular|nucleus|cytoplasm|cytoplasm|plasma membrane|membrane|neuromuscular junction|sarcolemma|,"immune system process|regulation of transcription, DNA-templated|protein phosphorylation|membrane protein ectodomain proteolysis|inflammatory response|regulation of G2/M transition of mitotic cell cycle|phosphorylation|positive regulation of interleukin-17 production|positive regulation of interleukin-4 production|intracellular signal transduction|intracellular signal transduction|positive regulation of T cell proliferation|positive regulation of NF-kappaB import into nucleus|positive regulation of interleukin-2 biosynthetic process|negative regulation of insulin receptor signaling pathway|positive regulation of protein secretion|positive regulation of T cell activation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of filopodium assembly|positive regulation of stress fiber assembly|negative regulation of T cell apoptotic process|regulation of platelet aggregation|positive regulation of T-helper 17 type immune response|positive regulation of T-helper 2 cell activation|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein kinase C activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.3,1.28,10,0.1,0.144,0,0,0,0.879,0,0,-1.6,1.2
ENSMUSG00000027203,DUT,deoxyuridine triphosphatase,nucleus|cytoplasm|mitochondrion|cytosol|extracellular vesicular exosome|,dUMP biosynthetic process|regulation of protein heterodimerization activity|dUTP catabolic process|protein homotrimerization|negative regulation of receptor activity|,dUTP diphosphatase activity|receptor inhibitor activity|pyrimidine deoxyribonucleotide binding|peroxisome proliferator activated receptor binding|poly(A) RNA binding|,5,0.2,0.201,4,0,0,0,0,0,0.879,0,0,-1.8,1.7
ENSMUSG00000055493,EPM2A,"epilepsy, progressive myoclonic epilepsy, type 2 gene alpha",nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|cytosol|cytosol|polysome|,carbohydrate metabolic process|glycogen metabolic process|protein dephosphorylation|autophagy|nervous system development|dephosphorylation|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|inositol phosphate dephosphorylation|habituation|,"phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|carbohydrate phosphatase activity|carbohydrate binding|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|starch binding|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.7,1.4
ENSMUSG00000024194,CUTA,cutA divalent cation tolerance homolog (E. coli),membrane|extracellular vesicular exosome|,protein localization|response to metal ion|protein homooligomerization|,enzyme binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000029869,EPHB6,Eph receptor B6,extracellular region|cell|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|parathyroid hormone secretion|ephrin receptor signaling pathway|calcium ion homeostasis|,"nucleotide binding|protein kinase activity|ephrin receptor activity|ATP binding|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.064,10,0,0,0,0,0,0.879,0,0,-1.6,1.6
ENSMUSG00000043301,KCNJ6,"potassium inwardly-rectifying channel, subfamily J, member 6",cytoplasm|Golgi apparatus|plasma membrane|cell surface|membrane|integral component of membrane|axon|dendrite|neuronal cell body membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|thyroid hormone metabolic process|potassium ion transmembrane transport|,G-protein alpha-subunit binding|inward rectifier potassium channel activity|voltage-gated ion channel activity|G-protein activated inward rectifier potassium channel activity|,10,0.2,0.664,10,0,0,0,0,0,0.879,0,0,-1.4,1.5
ENSMUSG00000040896,KCND3,"potassium voltage-gated channel, Shal-related family, member 3",plasma membrane|integral component of plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|dendrite|cell projection|neuron projection|neuronal cell body|perinuclear endoplasmic reticulum|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion export|potassium ion transmembrane transport|membrane repolarization|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|A-type (transient outward) potassium channel activity|A-type (transient outward) potassium channel activity|A-type (transient outward) potassium channel activity|potassium channel activity|protein binding|ion channel binding|metal ion binding|,10,-0.1,0.0318,10,0,0,0,0,0,0.879,0,0,-1.8,1.2
ENSMUSG00000039648,CCBL1,cysteine conjugate-beta lyase 1,nucleus|cytoplasm|,biosynthetic process|kynurenine metabolic process|L-kynurenine metabolic process|,catalytic activity|transaminase activity|kynurenine-oxoglutarate transaminase activity|transferase activity|lyase activity|pyridoxal phosphate binding|protein homodimerization activity|L-phenylalanine:pyruvate aminotransferase activity|glutamine-phenylpyruvate transaminase activity|cysteine-S-conjugate beta-lyase activity|L-glutamine:pyruvate aminotransferase activity|,9,0.1,0.117,9,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000050901,MTNR1B,melatonin receptor 1B,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|circadian rhythm|glucose homeostasis|regulation of insulin secretion|,signal transducer activity|G-protein coupled receptor activity|melatonin receptor activity|,10,0.8,0.57,10,0,0,0,0,0,0.879,0,0,-1,2
ENSMUSG00000009681,BCR,breakpoint cluster region,intracellular|cytoplasm|cytosol|plasma membrane|membrane|protein complex|extracellular vesicular exosome|,protein phosphorylation|signal transduction|brain development|phosphorylation|actin cytoskeleton organization|negative regulation of cell migration|response to lipopolysaccharide|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|inner ear morphogenesis|negative regulation of neutrophil degranulation|positive regulation of GTPase activity|protein autophosphorylation|platelet-derived growth factor receptor signaling pathway|negative regulation of inflammatory response|positive regulation of phagocytosis|neuromuscular process controlling balance|regulation of cell cycle|,nucleotide binding|protein serine/threonine kinase activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|GTPase activator activity|protein binding|ATP binding|kinase activity|transferase activity|enzyme binding|Rac GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1,2
ENSMUSG00000031618,NR3C2,"nuclear receptor subfamily 3, group C, member 2",nucleus|cytoplasm|endoplasmic reticulum|membrane|receptor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cellular sodium ion homeostasis|excretion|mineralocorticoid receptor signaling pathway|regulation of cell proliferation|steroid hormone mediated signaling pathway|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|steroid binding|steroid binding|protein binding|zinc ion binding|lipid binding|mineralocorticoid receptor activity|hormone binding|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,-0.1,0.122,10,0.1,0.132,0,0,0,0.879,0,0,-1.7,1.3
ENSMUSG00000048550,THNSL1,threonine synthase-like 1 (bacterial),nucleus|cytoplasm|mitochondrion|,biological_process|,molecular_function|,10,-0.1,0.264,10,0,0,0,0,0,0.879,0,0,-1.1,1.9
ENSMUSG00000007030,VWA7,von Willebrand factor A domain containing 7,extracellular region|,None,None,10,-0.1,0.206,10,0.2,0.453,0,0,0,0.879,0,0,-1,1.9
ENSMUSG00000009376,MET,met proto-oncogene,extracellular space|cytoplasm|plasma membrane|basal plasma membrane|postsynaptic density|membrane|integral component of membrane|dendrite|sperm flagellum|neuron projection|neuronal cell body|postsynaptic membrane|excitatory synapse|,negative regulation of transcription from RNA polymerase II promoter|activation of MAPK activity|neuron migration|liver development|placenta development|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|brain development|muscle organ development|muscle organ development|skeletal muscle tissue development|positive regulation of gene expression|positive regulation of peptidyl-threonine phosphorylation|negative regulation of peptidyl-threonine phosphorylation|positive regulation of glucose transport|positive regulation of neuron projection development|muscle cell migration|myotube differentiation|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|sperm motility|adult behavior|positive regulation of peptidyl-serine phosphorylation|glucose homeostasis|positive regulation of DNA replication|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|protein autophosphorylation|hepatocyte growth factor receptor signaling pathway|hepatocyte growth factor receptor signaling pathway|branching morphogenesis of an epithelial tube|positive regulation of dendrite morphogenesis|regulation of synaptic transmission|positive chemotaxis|positive chemotaxis|myoblast proliferation|regulation of excitatory postsynaptic membrane potential|regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|negative regulation of hydrogen peroxide-mediated programmed cell death|positive regulation of endothelial cell chemotaxis|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor activity|hepatocyte growth factor-activated receptor activity|hepatocyte growth factor-activated receptor activity|protein binding|ATP binding|beta-catenin binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein phosphatase binding|protein complex binding|phospholipase binding|phosphatidylinositol 3-kinase binding|protein heterodimerization activity|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000020357,FLT4,FMS-like tyrosine kinase 4,nucleus|cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,angiogenesis|positive regulation of protein phosphorylation|positive regulation of endothelial cell proliferation|vasculature development|lymph vessel development|lymph vessel development|lymphangiogenesis|lymphangiogenesis|sprouting angiogenesis|protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation vascular endothelial growth factor production|positive regulation of endothelial cell migration|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|positive regulation of cell growth|cellular response to vascular endothelial growth factor stimulus|vascular endothelial growth factor signaling pathway|vascular endothelial growth factor signaling pathway|negative regulation of apoptotic process|positive regulation of MAPK cascade|positive regulation of JNK cascade|protein autophosphorylation|vascular endothelial growth factor receptor signaling pathway|blood vessel morphogenesis|regulation of blood vessel remodeling|positive regulation of ERK1 and ERK2 cascade|positive regulation of protein kinase C signaling|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|vascular endothelial growth factor-activated receptor activity|vascular endothelial growth factor-activated receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|growth factor binding|protein phosphatase binding|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000063239,GRM4,"glutamate receptor, metabotropic 4",intracellular|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|presynaptic membrane|neuron projection|terminal bouton|dendritic shaft|presynaptic active zone membrane|,"activation of MAPK activity|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|synaptic transmission|learning|regulation of synaptic transmission, glutamatergic|",group III metabotropic glutamate receptor activity|group III metabotropic glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|calmodulin binding|glutamate receptor activity|calcium-dependent protein binding|,9,-0.2,0.545,9,0,0,0,0,0,0.879,0,0,-1.8,1.2
ENSMUSG00000036330,SLC18A1,"solute carrier family 18 (vesicular monoamine), member 1",cytoplasm|membrane|integral component of membrane|cytoplasmic vesicle|,transport|neurotransmitter transport|drug transport|positive regulation of dopamine secretion|ion transmembrane transport|serotonin uptake|negative regulation of serotonin uptake|transmembrane transport|,serotonin transmembrane transporter activity|drug transmembrane transporter activity|enzyme binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1,2
ENSMUSG00000042638,GUCY2C,guanylate cyclase 2c,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,cGMP biosynthetic process|cGMP biosynthetic process|cGMP biosynthetic process|protein phosphorylation|cyclic nucleotide biosynthetic process|response to toxic substance|intracellular signal transduction|regulation of cell proliferation|,"nucleotide binding|guanylate cyclase activity|guanylate cyclase activity|protein kinase activity|ATP binding|GTP binding|toxic substance binding|transferase activity, transferring phosphorus-containing groups|lyase activity|phosphorus-oxygen lyase activity|",10,0.1,0.327,10,-0.1,0.0167,0,0,0,0.879,0,0,-1,1.9
ENSMUSG00000027692,TNIK,TRAF2 and NCK interacting kinase,nucleus|cytoplasm|endosome|cytoskeleton|perinuclear region of cytoplasm|recycling endosome|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|cytoskeleton organization|activation of JNKK activity|nervous system development|Wnt signaling pathway|phosphorylation|signal transduction by phosphorylation|actin cytoskeleton reorganization|intracellular signal transduction|protein autophosphorylation|regulation of dendrite morphogenesis|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.3,0.386,10,0,0,0,0,0,0.879,0,0,-1.6,1.3
ENSMUSG00000039059,HRH3,histamine receptor H3,plasma membrane|membrane|integral component of membrane|neuron projection|myelin sheath|,regulation of neurotransmitter levels|signal transduction|G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|positive regulation of cytosolic calcium ion concentration|learning|memory|negative regulation of glutamate secretion|negative regulation of gamma-aminobutyric acid secretion|regulation of norepinephrine secretion|negative regulation of serotonin secretion|response to organic cyclic compound|eating behavior|drinking behavior|negative regulation of blood pressure|positive regulation of epithelial cell proliferation|cognition|,signal transducer activity|G-protein coupled receptor activity|histamine receptor activity|drug binding|,9,0,0,9,0,0,0,0,0,0.879,0,0,-1.6,1.6
ENSMUSG00000035064,EEF2K,eukaryotic elongation factor-2 kinase,None,translational elongation|protein phosphorylation|phosphorylation|regulation of protein autophosphorylation|protein autophosphorylation|,"nucleotide binding|protein serine/threonine kinase activity|elongation factor-2 kinase activity|elongation factor-2 kinase activity|calcium ion binding|calmodulin binding|calmodulin binding|ATP binding|translation factor activity, nucleic acid binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.1,0.157,0,0,0,0.879,0,0,-1.3,1.6
ENSMUSG00000051483,CBR1,carbonyl reductase 1,nucleus|cytoplasm|plasma membrane|microvillus|intracellular membrane-bounded organelle|extracellular vesicular exosome|,metabolic process|drug metabolic process|vitamin K metabolic process|oxidation-reduction process|oxidation-reduction process|,"carbonyl reductase (NADPH) activity|carbonyl reductase (NADPH) activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor|15-hydroxyprostaglandin dehydrogenase (NADP+) activity|prostaglandin-E2 9-reductase activity|",10,0.1,0.109,10,0,0,0,0,0,0.879,0,0,-1.1,1.8
ENSMUSG00000020227,IRAK3,interleukin-1 receptor-associated kinase 3,nucleus|nucleus|cytoplasm|cytoplasm|,negative regulation of cytokine-mediated signaling pathway|protein phosphorylation|protein phosphorylation|apoptotic process|signal transduction|response to virus|positive regulation of macrophage tolerance induction|negative regulation of macrophage cytokine production|phosphorylation|cytokine-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|response to peptidoglycan|response to lipopolysaccharide|negative regulation of interleukin-12 production|negative regulation of interleukin-12 production|negative regulation of interleukin-6 production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|negative regulation of tumor necrosis factor production|negative regulation of toll-like receptor signaling pathway|negative regulation of protein catabolic process|negative regulation of protein catabolic process|regulation of apoptotic process|negative regulation of protein complex disassembly|regulation of protein complex disassembly|response to exogenous dsRNA|negative regulation of MAP kinase activity|negative regulation of MAP kinase activity|negative regulation of innate immune response|protein autophosphorylation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|interleukin-1-mediated signaling pathway|interleukin-1-mediated signaling pathway|response to interleukin-1|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|protein heterodimerization activity|",10,-0.1,0.101,10,0.2,0.407,0,0,0,0.879,0,0,-1.1,1.9
ENSMUSG00000015202,CNKSR3,Cnksr family member 3,cellular_component|cytoplasm|membrane|,regulation of signal transduction|positive regulation of sodium ion transport|negative regulation of peptidyl-serine phosphorylation|negative regulation of ERK1 and ERK2 cascade|positive regulation of sodium ion transmembrane transporter activity|,molecular_function|,10,0,0,10,0.1,0.386,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000021070,BDKRB2,"bradykinin receptor, beta 2",endosome|plasma membrane|membrane|integral component of membrane|,acute inflammatory response to antigenic stimulus|smooth muscle contraction|response to stress|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|negative regulation of cell proliferation|response to salt stress|negative regulation of peptidyl-serine phosphorylation|maintenance of blood-brain barrier|vasoconstriction|vasodilation|negative regulation of blood pressure|arachidonic acid secretion|negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|,protease binding|signal transducer activity|G-protein coupled receptor activity|bradykinin receptor activity|beta-2 adrenergic receptor binding|type 1 angiotensin receptor binding|protein heterodimerization activity|,10,-0.1,0.0979,10,0.2,0.672,0,0,0,0.879,0,0,-1.2,1.6
ENSMUSG00000032251,IRAK1BP1,interleukin-1 receptor-associated kinase 1 binding protein 1,intracellular|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|I-kappaB kinase/NF-kappaB signaling|phosphorylation|",protein binding|kinase activity|transferase activity|,10,0.1,0.421,10,0,0,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000028573,FGGY,FGGY carbohydrate kinase domain containing,cellular_component|,carbohydrate metabolic process|phosphorylation|neuron cellular homeostasis|,"phosphofructokinase activity|phosphorylase kinase regulator activity|cobinamide kinase activity|phytol kinase activity|kinase activity|phosphatidylinositol phosphate kinase activity|cyclin-dependent protein serine/threonine kinase regulator activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|phenol kinase activity|cyclin-dependent protein kinase activating kinase regulator activity|inositol tetrakisphosphate 2-kinase activity|heptose 7-phosphate kinase activity|aminoglycoside phosphotransferase activity|phosphatidylinositol 3-kinase activity|eukaryotic elongation factor-2 kinase regulator activity|eukaryotic elongation factor-2 kinase activator activity|LPPG:FO 2-phospho-L-lactate transferase activity|cytidine kinase activity|glycerate 2-kinase activity|(S)-lactate 2-kinase activity|phosphoserine:homoserine phosphotransferase activity|L-seryl-tRNA(Sec) kinase activity|phosphocholine transferase activity|polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polynucleotide kinase activity|GTP-dependent polynucleotide kinase activity|farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|geraniol kinase activity|geranylgeraniol kinase activity|CTP:geranylgeraniol kinase activity|prenol kinase activity|1-phosphatidylinositol-5-kinase activity|1-phosphatidylinositol-3-phosphate 4-kinase activity|phosphatidylinositol-3,4-bisphosphate 5-kinase activity|phosphatidylinositol bisphosphate kinase activity|inositol-3,4,6-trisphosphate 1-kinase activity|inositol 5-diphosphate pentakisphosphate 5-kinase activity|inositol diphosphate tetrakisphosphate kinase activity|",10,0.1,0.0652,10,0,0,0,0,0,0.879,0,0,-1.5,1.3
ENSMUSG00000034683,PPP1R1C,"protein phosphatase 1, regulatory (inhibitor) subunit 1C",cellular_component|cytoplasm|,cell cycle|signal transduction|positive regulation of cell growth|negative regulation of catalytic activity|cell division|positive regulation of G1/S transition of mitotic cell cycle|,protein phosphatase inhibitor activity|,10,0,0,10,0.2,0.358,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000015083,C8G,"complement component 8, gamma polypeptide",extracellular region|membrane attack complex|extracellular space|extracellular vesicular exosome|blood microparticle|,"immune system process|complement activation, alternative pathway|complement activation, classical pathway|cytolysis|innate immune response|",complement binding|retinol binding|protein complex binding|small molecule binding|,9,-1,2.46,9,0,0,0,0,0,0.879,0,0,-2,0.7
ENSMUSG00000029710,EPHB4,Eph receptor B4,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,angiogenesis|cell migration involved in sprouting angiogenesis|heart morphogenesis|protein phosphorylation|cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|phosphorylation|peptidyl-tyrosine phosphorylation|protein autophosphorylation|ephrin receptor signaling pathway|ephrin receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000000594,GM2A,GM2 ganglioside activator protein,mitochondrion|lysosome|,lipid metabolic process|sphingolipid metabolic process|ganglioside catabolic process|learning or memory|oligosaccharide catabolic process|lipid storage|positive regulation of catalytic activity|neurological system process|neuromuscular process controlling balance|,beta-N-acetylhexosaminidase activity|enzyme activator activity|hydrolase activity|,10,-0.2,0.355,10,0,0,0,0,0,0.879,0,0,-1.3,1.9
ENSMUSG00000032492,PTH1R,parathyroid hormone 1 receptor,intracellular|nucleus|cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|brush border membrane|receptor complex|extracellular vesicular exosome|,"skeletal system development|ossification|chondrocyte differentiation|chondrocyte differentiation|osteoblast development|cellular calcium ion homeostasis|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cell proliferation|negative regulation of cell proliferation|bone mineralization|bone resorption|cell maturation|positive regulation of inositol phosphate biosynthetic process|",signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|parathyroid hormone receptor activity|parathyroid hormone receptor activity|parathyroid hormone receptor activity|peptide hormone binding|protein self-association|,10,-0.1,0.112,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000021773,COMTD1,catechol-O-methyltransferase domain containing 1,mitochondrion|membrane|integral component of membrane|,methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.1,0.0376,10,-0.1,0.0212,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000027187,CAT,catalase,mitochondrion|mitochondrial intermembrane space|lysosome|peroxisome|peroxisome|peroxisomal membrane|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,response to reactive oxygen species|osteoblast differentiation|ureteric bud development|response to hypoxia|kidney development|triglyceride metabolic process|response to oxidative stress|response to oxidative stress|response to oxidative stress|cholesterol metabolic process|aerobic respiration|UV protection|positive regulation of phosphatidylinositol 3-kinase signaling|hemoglobin metabolic process|negative regulation of NF-kappaB transcription factor activity|hydrogen peroxide catabolic process|hydrogen peroxide catabolic process|hydrogen peroxide catabolic process|negative regulation of apoptotic process|positive regulation of NF-kappaB transcription factor activity|protein tetramerization|protein homotetramerization|positive regulation of cell division|oxidation-reduction process|,"aminoacylase activity|catalase activity|catalase activity|catalase activity|peroxidase activity|receptor binding|antioxidant activity|oxidoreductase activity|oxidoreductase activity, acting on peroxide as acceptor|enzyme binding|heme binding|protein homodimerization activity|metal ion binding|NADP binding|",10,-0.2,0.762,10,0.3,1.1,0,0,0,0.879,0,0,-1.7,1.2
ENSMUSG00000070645,REN1,renin 1 structural,extracellular region|extracellular space|extracellular space|intracellular|cytoplasm|membrane|,kidney development|angiotensin maturation|angiotensin maturation|regulation of blood volume by renin-angiotensin|renin-angiotensin regulation of aldosterone production|proteolysis|proteolysis|regulation of blood pressure|hormone-mediated signaling pathway|response to organic substance|response to drug|drinking behavior|regulation of MAPK cascade|cell maturation|response to cAMP|response to cGMP|,endopeptidase activity|endopeptidase activity|aspartic-type endopeptidase activity|receptor binding|insulin-like growth factor receptor binding|peptidase activity|hydrolase activity|,9,0,0,9,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000027995,TLR2,toll-like receptor 2,cytoplasm|plasma membrane|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|cytoplasmic vesicle|Toll-like receptor 1-Toll-like receptor 2 protein complex|Toll-like receptor 2-Toll-like receptor 6 protein complex|cell projection|cell body|,microglial cell activation|toll-like receptor signaling pathway|response to molecule of bacterial origin|response to molecule of fungal origin|immune system process|positive regulation of leukocyte migration|cell surface pattern recognition receptor signaling pathway|MyD88-dependent toll-like receptor signaling pathway|leukotriene metabolic process|inflammatory response|immune response|signal transduction|I-kappaB phosphorylation|negative regulation of cell proliferation|response to bacterium|positive regulation of Wnt signaling pathway|central nervous system myelin formation|response to bacterial lipoprotein|response to peptidoglycan|negative regulation of interleukin-12 production|negative regulation of interleukin-17 production|positive regulation of chemokine production|positive regulation of chemokine production|positive regulation of interferon-beta production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-18 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of toll-like receptor signaling pathway|toll-like receptor 2 signaling pathway|positive regulation of NF-kappaB import into nucleus|detection of triacyl bacterial lipopeptide|detection of diacyl bacterial lipopeptide|positive regulation of tumor necrosis factor biosynthetic process|chloramphenicol transport|negative regulation of growth of symbiont in host|innate immune response|positive regulation of nitric oxide biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|nitric oxide metabolic process|positive regulation of oligodendrocyte differentiation|regulation of cytokine secretion|positive regulation of cytokine secretion|positive regulation of inflammatory response|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|positive regulation of NF-kappaB transcription factor activity|positive regulation of nitric-oxide synthase biosynthetic process|induction by symbiont of defense-related host nitric oxide production|positive regulation of macrophage cytokine production|response to fatty acid|cellular response to bacterial lipopeptide|cellular response to bacterial lipopeptide|cellular response to lipoteichoic acid|cellular response to lipoteichoic acid|cellular response to peptidoglycan|cellular response to diacyl bacterial lipopeptide|cellular response to triacyl bacterial lipopeptide|,receptor activity|transmembrane signaling receptor activity|protein binding|signaling pattern recognition receptor activity|triacyl lipopeptide binding|triacyl lipopeptide binding|diacyl lipopeptide binding|peptidoglycan binding|protein heterodimerization activity|protein heterodimerization activity|lipoteichoic acid binding|lipopeptide binding|,9,0,0,8,0,0,0,0,0,0.879,0,0,-1.1,2
ENSMUSG00000028737,ALDH4A1,"aldehyde dehydrogenase 4 family, member A1",mitochondrion|,glutamate biosynthetic process|proline metabolic process|proline biosynthetic process|metabolic process|oxidation-reduction process|,"1-pyrroline-5-carboxylate dehydrogenase activity|aldehyde dehydrogenase (NAD) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|identical protein binding|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.7
ENSMUSG00000040003,MAGI2,"membrane associated guanylate kinase, WW and PDZ domain containing 2",nucleus|cytoplasm|cytoplasm|endosome|late endosome|plasma membrane|plasma membrane|tight junction|postsynaptic density|membrane|cell junction|dendrite|slit diaphragm|neuron projection|protein complex|synapse|perinuclear region of cytoplasm|,positive regulation of receptor internalization|signal transduction|nervous system development|negative regulation of cell proliferation|positive regulation of neuron projection development|cytoplasmic transport|negative regulation of cell migration|positive regulation of phosphoprotein phosphatase activity|negative regulation of activin receptor signaling pathway|nerve growth factor signaling pathway|receptor clustering|protein heterooligomerization|negative regulation of protein kinase B signaling|SMAD protein signal transduction|mitotic cell cycle arrest|cellular response to nerve growth factor stimulus|,signal transducer activity|protein binding|phosphatase binding|receptor signaling complex scaffold activity|receptor signaling complex scaffold activity|PDZ domain binding|beta-1 adrenergic receptor binding|protein complex binding|SMAD binding|type II activin receptor binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000041736,TSPO,translocator protein,cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|nuclear membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,steroid biosynthetic process|ion transport|chloride transport|signal transduction|synaptic transmission|glial cell migration|positive regulation of necrotic cell death|negative regulation of tumor necrosis factor production|positive regulation of apoptotic process|negative regulation of nitric oxide biosynthetic process|behavioral response to pain|regulation of steroid biosynthetic process|positive regulation of mitochondrial depolarization|positive regulation of calcium ion transport|contact inhibition|positive regulation of glial cell proliferation|negative regulation of glial cell proliferation|positive regulation of reactive oxygen species metabolic process|,androgen binding|benzodiazepine receptor activity|,8,0,0,8,0,0,0,0,0,0.879,0,0,-1.7,1.5
ENSMUSG00000031444,F10,coagulation factor X,extracellular region|membrane|intracellular membrane-bounded organelle|,proteolysis|blood coagulation|hemostasis|positive regulation of protein kinase B signaling|,catalytic activity|serine-type endopeptidase activity|calcium ion binding|phospholipid binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.0238,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000029403,CDKL2,cyclin-dependent kinase-like 2 (CDC2-related kinase),nucleus|cytoplasm|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cyclin-dependent protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.1,0.081,10,0,0,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000029334,PRKG2,"protein kinase, cGMP-dependent, type II",plasma membrane|membrane|nuclear membrane|,protein phosphorylation|circadian rhythm|phosphorylation|circadian regulation of gene expression|peptidyl-serine autophosphorylation|protein targeting to plasma membrane|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|cGMP-dependent protein kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cGMP binding|protein homodimerization activity|",10,0.1,0.173,10,-0.1,0.143,0,0,0,0.879,0,0,-1.4,1.5
ENSMUSG00000073563,CSNK1G3,"casein kinase 1, gamma 3",cytoplasm|,protein phosphorylation|Wnt signaling pathway|phosphorylation|protein autophosphorylation|,"nucleotide binding|magnesium ion binding|glycoprotein binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|peptide binding|phosphoprotein binding|",9,-0.1,0.499,9,0,0,0,0,0,0.879,0,0,-1.7,1.3
ENSMUSG00000020524,GRIA1,"glutamate receptor, ionotropic, AMPA1 (alpha 1)",early endosome|endoplasmic reticulum|cytosol|plasma membrane|plasma membrane|synaptic vesicle|ionotropic glutamate receptor complex|cell surface|cell surface|postsynaptic density|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|neuromuscular junction|asymmetric synapse|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|dendrite membrane|cell projection|neuron projection|neuron projection|neuronal cell body|neuronal cell body|dendritic spine|dendritic spine|dendritic shaft|protein complex|axonal spine|neuron spine|neuron spine|synapse|postsynaptic membrane|excitatory synapse|,"regulation of receptor recycling|transport|ion transport|synaptic transmission|long-term memory|long-term memory|response to toxic substance|neuronal action potential|receptor internalization|receptor internalization|ion transmembrane transport|ion transmembrane transport|ionotropic glutamate receptor signaling pathway|ionotropic glutamate receptor signaling pathway|synaptic transmission, glutamatergic|positive regulation of membrane potential|regulation of synaptic plasticity|regulation of synaptic transmission|positive regulation of synaptic transmission|",G-protein alpha-subunit binding|receptor activity|ionotropic glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|ion channel activity|extracellular-glutamate-gated ion channel activity|protein binding|adenylate cyclase binding|protein kinase binding|protein domain specific binding|PDZ domain binding|small GTPase binding|myosin V binding|G-protein beta-subunit binding|beta-2 adrenergic receptor binding|identical protein binding|protein kinase A binding|,10,-0.1,0.211,10,0.2,0.736,0,0,0,0.879,0,0,-1.6,1.3
ENSMUSG00000032303,CHRNA3,"cholinergic receptor, nicotinic, alpha polypeptide 3",plasma membrane|acetylcholine-gated channel complex|acetylcholine-gated channel complex|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|neuronal cell body|synapse|postsynaptic membrane|,"transport|ion transport|cation transport|cation transport|regulation of muscle contraction|regulation of smooth muscle contraction|signal transduction|activation of transmembrane receptor protein tyrosine kinase activity|synaptic transmission|synaptic transmission, cholinergic|nervous system development|locomotory behavior|regulation of acetylcholine secretion, neurotransmission|ion transmembrane transport|behavioral response to nicotine|behavioral response to nicotine|regulation of membrane potential|response to drug|regulation of dendrite morphogenesis|protein heterooligomerization|regulation of excitatory postsynaptic membrane potential|synaptic transmission involved in micturition|synaptic transmission involved in micturition|",acetylcholine-activated cation-selective channel activity|acetylcholine-activated cation-selective channel activity|ion channel activity|extracellular ligand-gated ion channel activity|protein binding|drug binding|acetylcholine receptor activity|acetylcholine binding|protein heterodimerization activity|,9,0,0,9,0,0,0,0,0,0.879,0,0,-0.8,2
ENSMUSG00000000562,ADORA3,adenosine A3 receptor,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,adenosine receptor signaling pathway|adenosine receptor signaling pathway|histamine secretion by mast cell|histamine secretion by mast cell|positive regulation of leukocyte migration|positive regulation of leukocyte migration|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of mast cell degranulation|positive regulation of mast cell degranulation|positive regulation of inflammatory response|positive regulation of inflammatory response|positive regulation of calcium-mediated signaling|positive regulation of calcium-mediated signaling|positive regulation of mucus secretion|positive regulation of mucus secretion|,G-protein coupled adenosine receptor activity|G-protein coupled adenosine receptor activity|signal transducer activity|G-protein coupled receptor activity|,9,0,0,9,0,0,0,0,0,0.879,0,0,-1.2,1.8
ENSMUSG00000028024,ENPEP,glutamyl aminopeptidase,lysosomal membrane|plasma membrane|brush border|external side of plasma membrane|vesicle membrane|membrane|integral component of membrane|apical plasma membrane|cytoplasmic vesicle|vesicle lumen|apical part of cell|extracellular vesicular exosome|,angiogenesis|regulation of systemic arterial blood pressure by renin-angiotensin|proteolysis|proteolysis|cellular aromatic compound metabolic process|cell proliferation|cell migration|,aminopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|peptide binding|metal ion binding|metalloaminopeptidase activity|,9,0,0,9,0,0,0,0,0,0.879,0,0,-1.4,1.8
ENSMUSG00000028126,PIP5K1A,"phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha",nucleus|nucleus|cytoplasm|mRNA cleavage and polyadenylation specificity factor complex|plasma membrane|membrane|nuclear speck|lamellipodium|ruffle membrane|ruffle membrane|cell projection|,phospholipid biosynthetic process|fibroblast migration|phosphorylation|actin cytoskeleton reorganization|activation of Rac GTPase activity|phosphatidylinositol metabolic process|phosphatidylinositol phosphorylation|phosphatidylinositol phosphorylation|focal adhesion assembly|cell chemotaxis|protein targeting to plasma membrane|ruffle assembly|,nucleotide binding|protein binding|ATP binding|kinase activity|phosphatidylinositol phosphate kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|1-phosphatidylinositol-4-phosphate 5-kinase activity|transferase activity|kinase binding|,9,0.4,1.67,9,-0.2,0.308,0,0,0,0.879,0,0,-1.1,1.8
ENSMUSG00000049999,PPP1R3D,"protein phosphatase 1, regulatory subunit 3D",glycogen granule|intracellular membrane-bounded organelle|,carbohydrate metabolic process|glycogen metabolic process|regulation of glycogen biosynthetic process|regulation of glycogen catabolic process|dephosphorylation|,phosphoprotein phosphatase activity|enzyme binding|,10,-0.3,1.05,10,0,0,0,0,0,0.879,0,0,-1.6,1.3
ENSMUSG00000050089,AKAP4,A kinase (PRKA) anchor protein 4,nucleus|cilium|Z disc|motile cilium|motile cilium|sperm fibrous sheath|cell projection|perinuclear region of cytoplasm|sperm principal piece|,transmembrane receptor protein serine/threonine kinase signaling pathway|protein localization|phosphorylation|cell projection organization|sperm motility|sperm motility|,protein binding|kinase activity|transferase activity|protein kinase A binding|,9,0.6,0.795,9,0,0,0,0,0,0.879,0,0,-0.9,2
ENSMUSG00000028289,EPHA7,Eph receptor A7,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|dendrite|neuromuscular junction|neuronal cell body|postsynaptic membrane|,protein phosphorylation|apoptotic process|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|brain development|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|regulation of cell-cell adhesion|retinal ganglion cell axon guidance|regulation of protein autophosphorylation|positive regulation of apoptotic process|regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of neuron apoptotic process|ephrin receptor signaling pathway|ephrin receptor signaling pathway|branching morphogenesis of a nerve|regulation of peptidyl-tyrosine phosphorylation|regulation of peptidyl-tyrosine phosphorylation|negative chemotaxis|regulation of ERK1 and ERK2 cascade|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|GPI-linked ephrin receptor activity|protein binding|ATP binding|axon guidance receptor activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|chemorepellent activity|ephrin receptor binding|",9,0,0,9,0.1,0.0659,0,0,0,0.879,0,0,-1.1,1.9
ENSMUSG00000020331,HCN2,"hyperpolarization-activated, cyclic nucleotide-gated K+ 2",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|neuronal cell body|dendritic shaft|synapse|,transport|ion transport|potassium ion transport|sodium ion transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|regulation of membrane potential|positive regulation of heart contraction|transmembrane transport|cellular response to cAMP|cellular response to cGMP|potassium ion transmembrane transport|potassium ion transmembrane transport|,nucleotide binding|ion channel activity|intracellular cAMP activated cation channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|potassium channel activity|sodium channel activity|protein binding|PDZ domain binding|cAMP binding|protein complex scaffold|identical protein binding|,10,0.1,0.365,10,0,0,0,0,0,0.879,0,0,-1.1,1.8
ENSMUSG00000003623,CROT,carnitine O-octanoyltransferase,mitochondrion|peroxisome|peroxisome|intracellular membrane-bounded organelle|,generation of precursor metabolites and energy|lipid metabolic process|fatty acid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|transport|carnitine metabolic process|fatty acid transport|coenzyme A metabolic process|response to drug|medium-chain fatty acid metabolic process|,"receptor binding|carnitine O-octanoyltransferase activity|carnitine O-octanoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000003762,ADCK4,aarF domain containing kinase 4,cellular_component|cytoplasm|mitochondrion|plasma membrane|membrane|integral component of membrane|,biological_process|phosphorylation|,"molecular_function|protein serine/threonine kinase activity|transmembrane receptor protein serine/threonine kinase activity|3-phosphoinositide-dependent protein kinase activity|DNA-dependent protein kinase activity|AMP-activated protein kinase activity|cyclic nucleotide-dependent protein kinase activity|eukaryotic translation initiation factor 2alpha kinase activity|calcium-dependent protein kinase C activity|receptor signaling protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|JUN kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|ribosomal protein S6 kinase activity|MAP kinase kinase kinase kinase activity|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|SAP kinase activity|transmembrane receptor protein kinase activity|cyclin-dependent protein kinase activating kinase activity|GTP-dependent protein kinase activity|",10,0,0,10,-0.1,0.0397,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000027030,STK39,serine/threonine kinase 39,nucleus|cytoplasm|cytoskeleton|membrane|basolateral plasma membrane|apical plasma membrane|,protein phosphorylation|protein phosphorylation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|signal transduction by phosphorylation|signal transduction by phosphorylation|intracellular signal transduction|positive regulation of potassium ion transport|regulation of inflammatory response|negative regulation of potassium ion transmembrane transporter activity|negative regulation of potassium ion transmembrane transport|negative regulation of rubidium ion transport|negative regulation of rubidium ion transmembrane transporter activity|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|",10,-1,1.57,10,0,0,0,0,0,0.879,0,0,-2,0.6
ENSMUSG00000026564,DUSP27,dual specificity phosphatase 27 (putative),cellular_component|,protein dephosphorylation|dephosphorylation|,protein tyrosine/serine/threonine phosphatase activity|phosphatase activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000027843,PTPN22,"protein tyrosine phosphatase, non-receptor type 22 (lymphoid)",nucleus|nucleus|cytoplasm|cytoplasm|cytoplasmic side of plasma membrane|cytoplasmic side of plasma membrane|perinuclear region of cytoplasm|,immune system process|protein dephosphorylation|protein dephosphorylation|dephosphorylation|T cell differentiation|regulation of natural killer cell proliferation|peptidyl-tyrosine dephosphorylation|phosphoanandamide dephosphorylation|T cell receptor signaling pathway|negative regulation of T cell receptor signaling pathway|negative regulation of T cell activation|negative regulation of T cell activation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|phosphatase activity|SH3 domain binding|kinase binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.4,1.7
ENSMUSG00000005553,ATP4A,"ATPase, H+/K+ exchanging, gastric, alpha polypeptide",extracellular space|plasma membrane|membrane|integral component of membrane|apical plasma membrane|,ATP catabolic process|ATP biosynthetic process|transport|ion transport|cation transport|potassium ion transport|regulation of proton transport|monovalent inorganic cation transport|ATP hydrolysis coupled proton transport|proton transport|response to drug|response to drug|pH reduction|potassium ion transmembrane transport|hydrogen ion transmembrane transport|,"nucleotide binding|magnesium ion binding|ATP binding|hydrogen:potassium-exchanging ATPase activity|monovalent inorganic cation transmembrane transporter activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|cation-transporting ATPase activity|metal ion binding|protein heterodimerization activity|",9,-0.2,0.483,9,0.1,0.406,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000015968,CACNA1D,"calcium channel, voltage-dependent, L type, alpha 1D subunit",nucleus|plasma membrane|plasma membrane|integral component of plasma membrane|voltage-gated calcium channel complex|voltage-gated calcium channel complex|membrane|integral component of membrane|apical plasma membrane|Z disc|dendrite|dendrite membrane|sarcolemma|neuronal cell body|,transport|ion transport|calcium ion transport|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|sensory perception of sound|sensory perception of sound|calcium-mediated signaling|positive regulation of CREB transcription factor activity|regulation of ion transmembrane transport|regulation of calcium ion transport|positive regulation of calcium ion transport|transmembrane transport|regulation of atrial cardiac muscle cell membrane repolarization|calcium ion import|calcium ion import|calcium ion transmembrane transport|calcium ion transmembrane transport|divalent metal ion transport|membrane depolarization during SA node cell action potential|membrane depolarization during SA node cell action potential|membrane repolarization during SA node cell action potential|regulation of heart rate by cardiac conduction|regulation of heart rate by cardiac conduction|regulation of potassium ion transmembrane transporter activity|regulation of potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|high voltage-gated calcium channel activity|PDZ domain binding|ankyrin binding|ankyrin binding|metal ion binding|alpha-actinin binding|voltage-gated calcium channel activity involved SA node cell action potential|voltage-gated calcium channel activity involved SA node cell action potential|,9,-0.1,0.304,9,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000050917,FGF4,fibroblast growth factor 4,extracellular region|nucleus|cytosol|,cartilage condensation|positive regulation of protein phosphorylation|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|mesenchymal cell proliferation|regulation of gene expression|positive regulation of gene expression|stem cell maintenance|cell differentiation|embryonic limb morphogenesis|embryonic hindlimb morphogenesis|odontogenesis of dentin-containing tooth|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of cell division|cranial suture morphogenesis|apoptotic process involved in morphogenesis|chondroblast differentiation|positive regulation of ERK1 and ERK2 cascade|,receptor binding|fibroblast growth factor receptor binding|protein binding|growth factor activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.4,1.7
ENSMUSG00000033295,PTPRF,"protein tyrosine phosphatase, receptor type, F",endosome|plasma membrane|membrane|integral component of membrane|growth cone|neuron projection|neuronal cell body|intracellular membrane-bounded organelle|excitatory synapse|extracellular vesicular exosome|,negative regulation of cytokine-mediated signaling pathway|protein dephosphorylation|cell adhesion|homophilic cell adhesion|signal transduction|nervous system development|negative regulation of cell proliferation|dephosphorylation|cell migration|negative regulation of cell projection organization|peptidyl-tyrosine dephosphorylation|negative regulation of epidermal growth factor receptor signaling pathway|positive regulation of apoptotic process|positive regulation of neuron apoptotic process|negative regulation of insulin receptor signaling pathway|positive regulation of dendrite morphogenesis|regulation of synapse structure and activity|negative regulation of neurotrophin TRK receptor signaling pathway|negative regulation of receptor binding|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|transmembrane receptor protein tyrosine phosphatase activity|insulin receptor binding|heparin binding|hydrolase activity|phosphatase activity|receptor tyrosine kinase binding|protein complex binding|phosphate ion binding|,10,0.1,0.288,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000028661,EPHA8,Eph receptor A8,endosome|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell projection|neuron projection|,protein phosphorylation|substrate-dependent cell migration|cell adhesion|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|axon guidance|phosphorylation|neuron remodeling|peptidyl-tyrosine phosphorylation|regulation of cell adhesion|neuron projection development|regulation of cell adhesion mediated by integrin|positive regulation of MAPK cascade|positive regulation of phosphatidylinositol 3-kinase activity|protein autophosphorylation|ephrin receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ephrin receptor activity|GPI-linked ephrin receptor activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000037942,CRP,"C-reactive protein, pentraxin-related",extracellular region|extracellular space|filopodium|growth cone|extracellular vesicular exosome|,"acute-phase response|complement activation, classical pathway|negative regulation of macrophage derived foam cell differentiation|negative regulation of lipid storage|wound healing|protein polymerization|cellular response to calcium ion|positive regulation of dendrite development|",complement component C1q binding|calcium ion binding|cholesterol binding|low-density lipoprotein particle binding|protein homodimerization activity|metal ion binding|,10,0,0,10,-0.6,1.11,0,0,0,0.879,0,0,-1.9,1.2
ENSMUSG00000026667,UHMK1,U2AF homology motif (UHM) kinase 1,nucleus|cytoplasm|axon|dendrite cytoplasm|neuronal ribonucleoprotein granule|,protein phosphorylation|cell cycle arrest|phosphorylation|peptidyl-serine phosphorylation|neuron projection development|positive regulation of translational initiation|protein autophosphorylation|regulation of protein export from nucleus|,"nucleotide binding|nucleic acid binding|RNA binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|ribonucleoprotein complex binding|",9,-0.2,0.719,9,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000041891,LMAN1,"lectin, mannose-binding, 1",intracellular|cell|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|Golgi apparatus|membrane|membrane|integral component of membrane|sarcomere|ER to Golgi transport vesicle|intracellular membrane-bounded organelle|extracellular vesicular exosome|,transport|ER to Golgi vesicle-mediated transport|endoplasmic reticulum organization|Golgi organization|positive regulation of organelle organization|protein transport|vesicle-mediated transport|,identical protein binding|metal ion binding|,10,0.1,0.15,10,-0.6,1.17,0,0,0,0.879,0,0,-2,0.7
ENSMUSG00000000127,FER,ferris,None,locomotory behavior|,None,10,0,0,10,-0.1,0.0296,0,0,0,0.879,0,0,-2,0.8
ENSMUSG00000028698,PIK3R3,"phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)",phosphatidylinositol 3-kinase complex|,insulin receptor signaling pathway|regulation of phosphatidylinositol 3-kinase activity|regulation of phosphatidylinositol 3-kinase activity|,protein binding|1-phosphatidylinositol-3-kinase regulator activity|1-phosphatidylinositol-3-kinase regulator activity|,9,0,0,9,-0.6,0.301,0,0,0,0.879,0,0,-2,0.9
ENSMUSG00000064330,PDE6H,"phosphodiesterase 6H, cGMP-specific, cone, gamma",None,activation of MAPK activity|visual perception|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|response to stimulus|,"3',5'-cyclic-nucleotide phosphodiesterase activity|hydrolase activity|cGMP binding|3',5'-cyclic-GMP phosphodiesterase activity|",9,0.1,0.342,9,0,0,0,0,0,0.879,0,0,-1.3,1.8
ENSMUSG00000091705,H2-Q2,"histocompatibility 2, Q region locus 2",endoplasmic reticulum|Golgi apparatus|Golgi medial cisterna|cell surface|membrane|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|endoplasmic reticulum exit site|,immune system process|antigen processing and presentation of peptide antigen via MHC class I|,receptor binding|beta-2-microglobulin binding|peptide binding|peptide antigen binding|T cell receptor binding|poly(A) RNA binding|TAP binding|protein heterodimerization activity|,10,0,0,10,0.1,0.389,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000090231,CFB,complement factor B,extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,"immune system process|proteolysis|complement activation|complement activation, alternative pathway|complement activation, alternative pathway|cell proliferation|innate immune response|response to thyroid hormone|",catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,0.539,10,0,0,0,0,0,0.879,0,0,-1.8,1.2
ENSMUSG00000026925,INPP5E,inositol polyphosphate-5-phosphatase E,Golgi membrane|cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|cilium|axoneme|axoneme|membrane|cell projection|,lipid metabolic process|positive regulation of neuron projection development|dephosphorylation|phosphatidylinositol metabolic process|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|,"phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|inositol-polyphosphate 5-phosphatase activity|hydrolase activity|",9,-0.1,0.196,9,0,0,0,0,0,0.879,0,0,-1.8,1.2
ENSMUSG00000032373,CAR12,carbonic anyhydrase 12,cellular_component|membrane|integral component of membrane|,one-carbon metabolic process|regulation of pH|carbon dioxide transport|,carbonate dehydratase activity|zinc ion binding|lyase activity|metal ion binding|,10,0.1,0.485,10,0,0,0,0,0,0.879,0,0,-1.5,1.4
ENSMUSG00000019055,PLOD1,"procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1",endoplasmic reticulum|membrane|extracellular vesicular exosome|,epidermis development|peptidyl-lysine hydroxylation|oxidation-reduction process|,"iron ion binding|ferrous iron binding|procollagen-lysine 5-dioxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|L-ascorbic acid binding|peptide binding|metal ion binding|dioxygenase activity|",9,0,0,9,-0.3,0.617,0,0,0,0.879,0,0,-1.8,1.2
ENSMUSG00000026918,BRD3,bromodomain containing 3,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|chromatin modification|",chromatin binding|lysine-acetylated histone binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.7,1.4
ENSMUSG00000029310,NUDT9,nudix (nucleoside diphosphate linked moiety X)-type motif 9,mitochondrion|mitochondrion|extracellular vesicular exosome|,ADP catabolic process|IDP catabolic process|,hydrolase activity|adenosine-diphosphatase activity|ADP-ribose diphosphatase activity|,10,0,0,10,0.1,0.132,0,0,0,0.879,0,0,-1.1,1.9
ENSMUSG00000027223,MAPK8IP1,mitogen-activated protein kinase 8 interacting protein 1,nucleus|cytoplasm|cytoplasm|mitochondrion|endoplasmic reticulum|cytosol|cytosol|membrane|axon|dendrite|neuron projection|dendritic growth cone|axonal growth cone|cell body|dentate gyrus mossy fiber|synapse|perinuclear region of cytoplasm|,"regulation of transcription, DNA-templated|signal transduction|signal transduction|JUN phosphorylation|positive regulation of signal transduction|positive regulation of signal transduction|vesicle-mediated transport|negative regulation of apoptotic process|negative regulation of JUN kinase activity|regulation of JNK cascade|negative regulation of JNK cascade|negative regulation of intrinsic apoptotic signaling pathway|",MAP-kinase scaffold activity|MAP-kinase scaffold activity|protein binding|JUN kinase binding|kinesin binding|kinesin binding|protein kinase binding|mitogen-activated protein kinase kinase binding|mitogen-activated protein kinase kinase kinase binding|identical protein binding|,10,0,0,10,0.3,0.848,0,0,0,0.879,0,0,-1.1,1.8
ENSMUSG00000040213,CCBL2,cysteine conjugate-beta lyase 2,mitochondrion|,2-oxoglutarate metabolic process|cellular amino acid metabolic process|biosynthetic process|kynurenine metabolic process|L-kynurenine metabolic process|,catalytic activity|transaminase activity|kynurenine-oxoglutarate transaminase activity|transferase activity|lyase activity|pyridoxal phosphate binding|protein homodimerization activity|poly(A) RNA binding|kynurenine-glyoxylate transaminase activity|cysteine-S-conjugate beta-lyase activity|,8,0,0,8,0,0,0,0,0,0.879,0,0,-1.8,1.5
ENSMUSG00000020009,IFNGR1,interferon gamma receptor 1,endoplasmic reticulum|postsynaptic density|membrane|integral component of membrane|dendrite|vesicle|,None,cytokine binding|,10,-0.2,0.386,10,0,0,0,0,0,0.879,0,0,-1.5,1.4
ENSMUSG00000022433,CSNK1E,"casein kinase 1, epsilon",nucleus|nucleus|cytoplasm|ribonucleoprotein complex|,protein phosphorylation|protein phosphorylation|protein phosphorylation|circadian rhythm|Wnt signaling pathway|phosphorylation|negative regulation of Wnt signaling pathway|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|circadian regulation of gene expression|cellular protein localization|regulation of circadian rhythm|rhythmic process|positive regulation of canonical Wnt signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|",10,-0.1,0.073,10,0,0,0,0,0,0.879,0,0,-1.5,1.6
ENSMUSG00000069539,SCYL2,SCY1-like 2 (S. cerevisiae),intracellular|cell|cytoplasm|endosome|Golgi apparatus|membrane|cytoplasmic vesicle|,positive regulation of receptor internalization|protein phosphorylation|endosome to lysosome transport|negative regulation of canonical Wnt signaling pathway|receptor internalization involved in canonical Wnt signaling pathway|positive regulation of clathrin-mediated endocytosis|,"protein kinase activity|receptor binding|protein binding|ATP binding|transferase activity, transferring phosphorus-containing groups|",10,-0.3,0.65,10,0.2,0.331,0,0,0,0.879,0,0,-1.4,1.5
ENSMUSG00000049225,PDP1,pyruvate dehyrogenase phosphatase catalytic subunit 1,mitochondrion|mitochondrion|,protein dephosphorylation|peptidyl-threonine dephosphorylation|,magnesium ion binding|catalytic activity|phosphoprotein phosphatase activity|protein serine/threonine phosphatase activity|magnesium-dependent protein serine/threonine phosphatase activity|[pyruvate dehydrogenase (lipoamide)] phosphatase activity|calcium ion binding|hydrolase activity|protein complex binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.9,1.1
ENSMUSG00000024866,ACY3,aspartoacylase (aminoacylase) 3,cytoplasm|plasma membrane|membrane|apical plasma membrane|extracellular vesicular exosome|,metabolic process|,"aminoacylase activity|protein binding|hydrolase activity|hydrolase activity, acting on ester bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|identical protein binding|identical protein binding|metal ion binding|",10,0.1,0.00243,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000041920,SLC16A6,"solute carrier family 16 (monocarboxylic acid transporters), member 6",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,-0.1,0.342,10,0,0,0,0,0,0.879,0,0,-1.4,1.6
ENSMUSG00000019102,ALDH3A1,"aldehyde dehydrogenase family 3, subfamily A1",extracellular space|cytoplasm|cytoplasm|endoplasmic reticulum|cytosol|plasma membrane|,response to hypoxia|cellular aldehyde metabolic process|metabolic process|positive regulation of cell proliferation|response to organic cyclic compound|response to drug|response to glucocorticoid|response to cAMP|oxidation-reduction process|oxidation-reduction process|,"3-chloroallyl aldehyde dehydrogenase activity|3-chloroallyl aldehyde dehydrogenase activity|3-chloroallyl aldehyde dehydrogenase activity|aldehyde dehydrogenase (NAD) activity|aldehyde dehydrogenase [NAD(P)+] activity|alcohol dehydrogenase (NADP+) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|",10,0.1,0.0385,10,0,0,0,0,0,0.879,0,0,-1.6,1.4
ENSMUSG00000020017,HAL,histidine ammonia lyase,cytoplasm|,histidine metabolic process|histidine catabolic process|biosynthetic process|,catalytic activity|histidine ammonia-lyase activity|histidine ammonia-lyase activity|lyase activity|ammonia-lyase activity|,10,-0.1,0.303,10,0,0,0,0,0,0.879,0,0,-1.6,1.3
ENSMUSG00000001583,TNK1,"tyrosine kinase, non-receptor, 1",cytoplasm|cytosol|membrane|cell junction|,protein phosphorylation|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|negative regulation of cell growth|negative regulation of Ras protein signal transduction|protein autophosphorylation|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",9,0.2,0.0675,10,0,0,0,0,0,0.879,0,0,-1.3,1.7
ENSMUSG00000038205,PRKAB2,"protein kinase, AMP-activated, beta 2 non-catalytic subunit",cytoplasm|cAMP-dependent protein kinase complex|apical plasma membrane|AMP-activated protein kinase complex|,protein phosphorylation|protein phosphorylation|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|,AMP-activated protein kinase activity|AMP-activated protein kinase activity|protein kinase binding|identical protein binding|,10,0.1,0.446,10,0,0,0,0,0,0.879,0,0,-1.4,1.5
ENSMUSG00000050541,ADRA1B,"adrenergic receptor, alpha 1b",nucleus|plasma membrane|intercalated disc|membrane|integral component of membrane|T-tubule|nuclear membrane|,blood vessel remodeling|response to amphetamine|vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure|positive regulation of heart rate by epinephrine-norepinephrine|positive regulation of the force of heart contraction by epinephrine-norepinephrine|regulation of muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|adult heart development|locomotory behavior|visual learning|response to hormone|cell growth|regulation of vasoconstriction|negative regulation of Rho protein signal transduction|organ growth|glucose homeostasis|response to morphine|positive regulation of MAPK cascade|negative regulation of glycogen catabolic process|positive regulation of glycogen catabolic process|behavioral response to cocaine|response to steroid hormone|regulation of cardiac muscle contraction|adrenergic receptor signaling pathway|adrenergic receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|adrenergic receptor activity|alpha1-adrenergic receptor activity|alpha1-adrenergic receptor activity|alpha1-adrenergic receptor activity|alpha1-adrenergic receptor activity|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.6,1.5
ENSMUSG00000061288,TAOK3,TAO kinase 3,intracellular|cytoplasm|,MAPK cascade|MAPK cascade|activation of MAPKK activity|DNA repair|protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|phosphorylation|G2 DNA damage checkpoint|positive regulation of stress-activated MAPK cascade|positive regulation of JUN kinase activity|negative regulation of JNK cascade|positive regulation of JNK cascade|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.445,10,0,0,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000036966,SPRYD3,SPRY domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.879,0,0,-1.5,1.5
ENSMUSG00000062209,ERBB4,v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian),nucleus|cytoplasm|mitochondrion|plasma membrane|caveola|postsynaptic density|membrane|integral component of membrane|basolateral plasma membrane|receptor complex|membrane raft|,"neural crest cell migration|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|nervous system development|heart development|lactation|lactation|positive regulation of cell proliferation|negative regulation of cell proliferation|embryonic pattern specification|negative regulation of muscle cell apoptotic process|phosphorylation|cell migration|peptidyl-tyrosine phosphorylation|central nervous system morphogenesis|olfactory bulb interneuron differentiation|regulation of cell migration|positive regulation of cell migration|positive regulation of synaptic transmission, GABAergic|positive regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of apoptotic process|surfactant homeostasis|mitochondrial fragmentation involved in apoptotic process|cell fate commitment|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of glucose import|protein autophosphorylation|positive regulation of epithelial cell proliferation|positive regulation of cardiac muscle cell proliferation|synapse maturation|mammary gland epithelial cell differentiation|mammary gland alveolus development|cardiac muscle tissue regeneration|positive regulation of ERK1 and ERK2 cascade|positive regulation of STAT protein import into nucleus|positive regulation of STAT protein import into nucleus|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity|epidermal growth factor receptor binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein homodimerization activity|transcription regulatory region DNA binding|",10,0,0,10,0,0,0,0,0,0.879,0,0,-1.7,1.4
ENSMUSG00000030447,CYFIP1,cytoplasmic FMR1 interacting protein 1,cytoplasm|mRNA cap binding complex|lamellipodium|cell junction|SCAR complex|cell projection|neuron projection|synapse|perinuclear region of cytoplasm|extracellular vesicular exosome|,multicellular organismal development|nervous system development|regulation of cell shape|Rac protein signal transduction|lamellipodium assembly|cell differentiation|axon extension|cognition|positive regulation of Arp2/3 complex-mediated actin nucleation|,actin binding|protein binding|profilin binding|protein complex binding|Rac GTPase binding|,10,2.6,112,10,2.7,161,2.6,273,273,1.00E-05,1,1,2.3,3.3
ENSMUSG00000070934,RRAGA,Ras-related GTP binding A,nucleus|cytoplasm|lysosome|lysosomal membrane|Golgi apparatus|intracellular membrane-bounded organelle|,apoptotic process|cell death|modulation by virus of host morphology or physiology|cellular protein localization|regulation of cytolysis|positive regulation of cytolysis|cellular response to amino acid stimulus|,nucleotide binding|GTP binding|protein homodimerization activity|protein heterodimerization activity|phosphoprotein binding|,10,2.1,99.4,10,1.7,101,2,198,198,1.00E-05,1,1,1.6,2.5
ENSMUSG00000028106,RPRD2,regulation of nuclear pre-mRNA domain containing 2,"DNA-directed RNA polymerase II, holoenzyme|",biological_process|,molecular_function|,10,-2.1,102,10,-1.9,57.8,-2,159,-159,1.00E-05,1,1,-2.6,-1.6
ENSMUSG00000073775,KTI12,"KTI12 homolog, chromatin associated (S. cerevisiae)",cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,2,64.1,10,1.6,85.2,1.8,148,148,1.00E-05,1,1,1.5,2.4
ENSMUSG00000028745,CAPZB,"capping protein (actin filament) muscle Z-line, beta",acrosomal vesicle|cytoplasm|cytoskeleton|F-actin capping protein complex|F-actin capping protein complex|intercalated disc|intercalated disc|membrane|Z disc|Z disc|lamellipodium|cortical cytoskeleton|extracellular vesicular exosome|WASH complex|,cytoskeleton organization|regulation of cell morphogenesis|cell projection organization|lamellipodium assembly|actin cytoskeleton organization|negative regulation of microtubule polymerization|neuron projection development|muscle fiber development|barbed-end actin filament capping|actin filament capping|regulation of protein kinase C signaling|,actin binding|protein binding|protein binding|beta-tubulin binding|actin filament binding|,10,1.5,27.4,9,2.4,119,2.3,142,142,1.00E-05,1,1,1.8,3
ENSMUSG00000048865,ARHGAP30,Rho GTPase activating protein 30,intracellular|cytoplasmic vesicle|intracellular membrane-bounded organelle|,signal transduction|,molecular_function|GTPase activator activity|,10,1.7,54.6,10,1.8,82,1.7,136,136,1.00E-05,1,1,1.4,2.2
ENSMUSG00000009090,AP1B1,"adaptor protein complex AP-1, beta 1 subunit",Golgi apparatus|trans-Golgi network|membrane|membrane coat|clathrin adaptor complex|cytoplasmic vesicle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|clathrin coat assembly|,protein binding|protein transporter activity|,10,1.8,56.3,10,1.3,69.8,1.6,124,124,1.00E-05,1,1,1.2,2.1
ENSMUSG00000020590,SNX13,sorting nexin 13,endosome|early endosome|membrane|,transport|intracellular protein transport|negative regulation of signal transduction|protein transport|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,lipid binding|phosphatidylinositol binding|,10,1.6,50.9,10,1.8,58.9,1.8,109,109,1.00E-05,1,1,1.4,2.3
ENSMUSG00000054405,DNAJC8,"DnaJ (Hsp40) homolog, subfamily C, member 8",cellular_component|,None,None,10,2,61.8,10,1.8,42.2,1.9,103,103,1.00E-05,1,1,1.5,2.6
ENSMUSG00000025044,MSR1,macrophage scavenger receptor 1,collagen trimer|cytosol|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|low-density lipoprotein particle|,endocytosis|receptor-mediated endocytosis|positive regulation of macrophage derived foam cell differentiation|positive regulation of cholesterol storage|cholesterol transport|plasma lipoprotein particle clearance|lipoprotein transport|,scavenger receptor activity|low-density lipoprotein particle binding|,10,-1.6,36,10,-1.5,67,-1.6,102,-102,1.00E-05,1,1,-2.1,-1.3
ENSMUSG00000090841,MYL6,"myosin, light polypeptide 6, alkali, smooth muscle and non-muscle",membrane|myosin complex|unconventional myosin complex|extracellular vesicular exosome|,muscle contraction|skeletal muscle tissue development|muscle filament sliding|,motor activity|calcium ion binding|structural constituent of muscle|structural constituent of muscle|,10,1.2,25.5,10,1.6,67,1.4,90.7,90.7,1.00E-05,1,1,1.1,1.9
ENSMUSG00000032437,STT3B,"STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,protein glycosylation|glycoprotein catabolic process|response to unfolded protein|protein N-linked glycosylation via asparagine|ER-associated ubiquitin-dependent protein catabolic process|co-translational protein modification|post-translational protein modification|,oligosaccharyl transferase activity|dolichyl-diphosphooligosaccharide-protein glycotransferase activity|transferase activity|,10,1.2,31.8,10,1.5,58.4,1.3,88.5,88.5,1.00E-05,1,1,1.1,1.8
ENSMUSG00000020917,ACLY,ATP citrate lyase,intracellular|nucleus|cytoplasm|mitochondrion|plasma membrane|membrane|extracellular vesicular exosome|,acetyl-CoA metabolic process|acetyl-CoA biosynthetic process|citrate metabolic process|lipid metabolic process|fatty acid biosynthetic process|metabolic process|lipid biosynthetic process|cellular carbohydrate metabolic process|,"nucleotide binding|catalytic activity|ATP citrate synthase activity|ATP citrate synthase activity|succinate-CoA ligase (ADP-forming) activity|protein binding|ATP binding|transferase activity|metal ion binding|transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer|cofactor binding|",10,1.1,27.1,10,1.5,50.6,1.3,75.7,75.7,2.00E-05,1,1,0.9,1.8
ENSMUSG00000026425,SRGAP2,SLIT-ROBO Rho GTPase activating protein 2,intracellular|nucleus|cytoplasm|mitochondrial inner membrane|cytosol|plasma membrane|plasma membrane|postsynaptic density|membrane|lamellipodium|cell junction|cytoplasmic vesicle|cell projection|dendritic spine head|synapse|postsynaptic membrane|phagocytic vesicle|,lamellipodium assembly involved in ameboidal cell migration|signal transduction|nervous system development|extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration|positive regulation of Rac GTPase activity|positive regulation of Rac GTPase activity|substrate adhesion-dependent cell spreading|filopodium assembly|filopodium assembly|neuron projection morphogenesis|actin filament severing|dendritic spine development|dendritic spine development|negative regulation of neuron migration|,GTPase activator activity|protein binding|Rac GTPase activator activity|Rac GTPase activator activity|protein homodimerization activity|protein homodimerization activity|Rac GTPase binding|Rac GTPase binding|,10,-0.9,44.7,10,-0.9,30.6,-0.9,74.9,-74.9,3.00E-05,1,1,-1.2,-0.7
ENSMUSG00000027423,SNX5,sorting nexin 5,cytoplasm|endosome|plasma membrane|membrane|extrinsic component of cytoplasmic side of plasma membrane|extrinsic component of endosome membrane|cytoplasmic vesicle|early endosome membrane|cell projection|macropinocytic cup|,transport|intracellular protein transport|endocytosis|pinocytosis|protein transport|,lipid binding|phosphatidylinositol binding|phosphatidylinositol binding|,10,-1.6,46.9,9,-1.6,25.4,-1.6,71.9,-71.9,3.00E-05,1,1,-2,-0.8
ENSMUSG00000047675,RPS8,ribosomal protein S8,intracellular|nucleus|cytoplasm|ribosome|membrane|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|translation|translational elongation|",structural constituent of ribosome|poly(A) RNA binding|,5,-1.8,72.7,4,0.2,0.372,-1.7,70.3,-70.3,3.00E-05,1,1,-2.9,-1.3
ENSMUSG00000031696,VPS35,vacuolar protein sorting 35,cytoplasm|lysosomal membrane|endosome|vacuole|cytosol|membrane|integral component of membrane|retromer complex|extracellular vesicular exosome|,"vacuolar protein processing|transport|protein transport|retrograde transport, endosome to Golgi|",protein binding|,10,1,28.6,10,1.3,42.4,1.2,69.9,69.9,3.00E-05,1,1,0.8,1.6
ENSMUSG00000042111,CCDC115,coiled-coil domain containing 115,lysosome|endosome|membrane|,biological_process|,molecular_function|,10,1.9,60.9,10,0.7,14.6,1.7,68.8,68.8,3.00E-05,1,1,1.2,2.5
ENSMUSG00000027822,SLC33A1,"solute carrier family 33 (acetyl-CoA transporter), member 1",endoplasmic reticulum|membrane|membrane|integral component of membrane|,transport|,acetyl-CoA transporter activity|,10,1.8,30.4,10,1.7,37.7,1.7,67.7,67.7,3.00E-05,1,1,1.3,2.3
ENSMUSG00000006906,STAMBP,STAM binding protein,nucleus|cytoplasm|endosome|plasma membrane|membrane|cleavage furrow|cleavage furrow|extracellular vesicular exosome|,mitotic cytokinesis|proteolysis|negative regulation of phosphatidylinositol 3-kinase signaling|protein deubiquitination|protein deubiquitination|negative regulation of neuron apoptotic process|negative regulation of Ras protein signal transduction|,ubiquitin-specific protease activity|peptidase activity|metallopeptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|metal ion binding|,10,-1.7,45.9,8,-1.6,22.1,-1.7,67.3,-67.3,3.00E-05,1,1,-2.2,-1
ENSMUSG00000039087,RREB1,ras responsive element binding protein 1,nucleus|cytoplasm|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,1.1,22.4,10,1.2,42.4,1.2,64.3,64.3,4.00E-05,1,1,0.9,1.6
ENSMUSG00000042229,RABIF,RAB interacting factor,cellular_component|,transport|small GTPase mediated signal transduction|biological_process|protein transport|,guanyl-nucleotide exchange factor activity|zinc ion binding|metal ion binding|,10,1.7,38.5,10,1.3,27,1.5,63.9,63.9,4.00E-05,1,1,1.1,2.2
ENSMUSG00000028437,UBAP1,ubiquitin-associated protein 1,ESCRT I complex|cytoplasm|endosome|cytosol|,transport|protein transport|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|,ubiquitin binding|,9,-1.4,35.8,9,-1.2,27.2,-1.3,62.3,-62.3,4.00E-05,1,1,-1.8,-0.7
ENSMUSG00000062376,2010012O05RIK,RIKEN cDNA 2010012O05 gene,cellular_component|,biological_process|,molecular_function|,10,1,18.2,10,1.7,45.9,1.5,60.5,60.5,5.00E-05,1,1,1,2.1
ENSMUSG00000047539,FBXO28,F-box protein 28,cellular_component|,biological_process|,molecular_function|,10,-0.9,37.3,10,-0.9,22,-0.9,58.8,-58.8,7.00E-05,1,1,-1.3,-0.7
ENSMUSG00000027411,VPS16,vacuolar protein sorting 16 (yeast),cytoplasm|lysosome|lysosomal membrane|endosome|early endosome|early endosome|late endosome|actin filament|membrane|axon|HOPS complex|neuronal cell body|recycling endosome|,transport|intracellular protein transport|protein transport|viral entry into host cell|,actin binding|protein binding|actin filament binding|,10,0.6,5.6,10,1.5,55.9,1.4,58.3,58.3,8.00E-05,1,1,0.9,2
ENSMUSG00000050106,TMC8,transmembrane channel-like gene family 8,extracellular space|cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|nuclear membrane|extracellular vesicular exosome|,regulation of cell growth|transport|ion transport|negative regulation of protein binding|negative regulation of protein oligomerization|zinc ion homeostasis|regulation of extrinsic apoptotic signaling pathway via death domain receptors|,receptor binding|,10,0.8,19.5,10,1.7,40.1,0.8,57.9,57.9,8.00E-05,1,1,0.6,1.7
ENSMUSG00000066148,PRPF4,PRP4 pre-mRNA processing factor 4 homolog (yeast),nucleus|spliceosomal complex|Cajal body|U4/U6 x U5 tri-snRNP complex|U4/U6 snRNP|,"mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",molecular_function|,10,1,6.96,10,1.5,51.1,1.3,56.4,56.4,9.00E-05,1,1,1,2
ENSMUSG00000068328,AUP1,ancient ubiquitous protein 1,endoplasmic reticulum|membrane|membrane|integral component of membrane|,metabolic process|,"transferase activity, transferring acyl groups|",10,1.3,18.1,10,1.4,36.1,1.4,53.6,53.6,0.00015,1,1,1,1.9
ENSMUSG00000042502,CD2BP2,CD2 antigen (cytoplasmic tail) binding protein 2,nucleus|nucleoplasm|U5 snRNP|cytoplasm|nuclear speck|,mRNA processing|RNA splicing|negative regulation of phosphatase activity|,ribonucleoprotein complex binding|,10,1.3,16.8,10,1.6,36.4,1.5,52,52,0.00026,1,1,1,2.1
ENSMUSG00000041515,IRF8,interferon regulatory factor 8,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|phagocytosis|immune response|response to bacterium|myeloid cell differentiation|positive regulation of interferon-gamma production|positive regulation of interleukin-12 production|defense response to bacterium|defense response to protozoan|negative regulation of growth of symbiont in host|positive regulation of transcription, DNA-templated|positive regulation of transcription initiation from RNA polymerase II promoter|cellular response to lipopolysaccharide|",regulatory region DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,8,1.4,22.3,7,1.9,31,1.7,51.4,51.4,0.00029,1,1,1.1,2.6
ENSMUSG00000018761,MPDU1,mannose-P-dolichol utilization defect 1,mitochondrion|endoplasmic reticulum|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|oligosaccharide biosynthetic process|,molecular_function|,10,1.1,33.2,10,0.9,18.4,1,50.7,50.7,0.00033,1,1,0.8,1.4
ENSMUSG00000025737,WDR24,WD repeat domain 24,cellular_component|,biological_process|,molecular_function|,10,1,26.3,10,0.6,26.4,0.8,50.6,50.6,0.00035,1,1,0.6,1.2
ENSMUSG00000039041,ADRM1,adhesion regulating molecule 1,proteasome complex|nucleus|cytoplasm|plasma membrane|,ovarian follicle development|transcription elongation from RNA polymerase II promoter|spermatid development|positive regulation of endopeptidase activity|regulation of T cell differentiation in thymus|follicle-stimulating hormone signaling pathway|proteasome assembly|oogenesis|thymus development|Sertoli cell development|positive regulation of growth hormone receptor signaling pathway|adipose tissue development|seminiferous tubule development|,protease binding|endopeptidase activator activity|proteasome binding|,8,1.5,12.3,8,1.7,38.2,1.6,49.9,49.9,0.00044,1,1,1.2,2.5
ENSMUSG00000029578,WIPI2,"WD repeat domain, phosphoinositide interacting 2",pre-autophagosomal structure|nucleus|cytoplasm|cytosol|membrane|pre-autophagosomal structure membrane|protein complex|,autophagic vacuole assembly|autophagy|,"phosphatidylinositol-3-phosphate binding|phosphatidylinositol-3,5-bisphosphate binding|",9,2.4,24.6,8,1.9,26,2.2,49.3,49.3,0.0005,1,1,1.7,3.9
ENSMUSG00000027361,GABPB1,"GA repeat binding protein, beta 1",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",transcription regulatory region DNA binding|protein heterodimerization activity|,10,0.6,10.7,9,1.5,37.1,0.6,45.4,45.4,0.00102,1,1,0.4,1.6
ENSMUSG00000029836,CBX3,chromobox 3,chromatin|chromatin|nucleus|nucleus|nuclear euchromatin|nuclear heterochromatin|nuclear heterochromatin|spindle|chromocenter|,"negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",protein binding|enzyme binding|protein domain specific binding|identical protein binding|histone methyltransferase binding|,10,0.8,17.3,10,0.8,26.9,0.8,43.8,43.8,0.00114,1,1,0.5,1.1
ENSMUSG00000041355,SSR2,"signal sequence receptor, beta",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.8,18.4,10,-0.8,24.9,-0.8,42.9,-42.9,0.00128,1,1,-1.3,-0.6
ENSMUSG00000020198,AP3D1,"adaptor-related protein complex 3, delta 1 subunit",intracellular|cell|cytoplasm|lysosomal membrane|Golgi apparatus|trans-Golgi network|endosome membrane|endosome membrane|membrane|membrane|membrane coat|axon|terminal bouton|,"transport|zinc ion transport|intracellular protein transport|intracellular protein transport|anterograde axon cargo transport|protein transport|vesicle-mediated transport|antigen processing and presentation|protein localization to organelle|endosome to melanosome transport|antigen processing and presentation, exogenous lipid antigen via MHC class Ib|anterograde synaptic vesicle transport|synaptic vesicle membrane organization|positive regulation of NK T cell differentiation|regulation of sequestering of zinc ion|regulation of sequestering of zinc ion|protein localization to membrane|",protein transporter activity|,10,0.8,18.9,10,0.7,22.7,0.8,41.2,41.2,0.00139,1,1,0.6,1.2
ENSMUSG00000034893,COG3,component of oligomeric golgi complex 3,nucleus|cytoplasm|Golgi apparatus|cis-Golgi network|plasma membrane|membrane|Golgi transport complex|,"protein glycosylation|transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|retrograde vesicle-mediated transport, Golgi to ER|intra-Golgi vesicle-mediated transport|protein transport|protein localization to organelle|protein stabilization|",protein transporter activity|,10,-0.4,1.89,10,1.5,43.3,1.5,41,41,0.00141,1,1,1,2.5
ENSMUSG00000066036,UBR4,ubiquitin protein ligase E3 component n-recognin 4,nucleus|cytoplasm|centrosome|cytoskeleton|membrane|membrane|integral component of membrane|,protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|protein binding|calmodulin binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,18.3,10,-1.7,30.7,-1.4,39.3,-39.3,0.00155,0,1,-2,-0.7
ENSMUSG00000059363,FXN,frataxin,cytoplasm|mitochondrion|mitochondrion|cytosol|,oxidative phosphorylation|heme biosynthetic process|transport|ion transport|cellular iron ion homeostasis|cellular iron ion homeostasis|mitochondrion organization|adult walking behavior|positive regulation of cell proliferation|aerobic respiration|embryo development ending in birth or egg hatching|response to iron ion|regulation of ferrochelatase activity|iron-sulfur cluster assembly|protein autoprocessing|iron incorporation into metallo-sulfur cluster|proprioception|positive regulation of cell growth|negative regulation of multicellular organism growth|negative regulation of apoptotic process|positive regulation of axon extension|negative regulation of organ growth|positive regulation of metalloenzyme activity|positive regulation of transferase activity|positive regulation of lyase activity|positive regulation of oxidoreductase activity|iron ion homeostasis|oxidation-reduction process|cellular response to hydrogen peroxide|negative regulation of release of cytochrome c from mitochondria|,"ferroxidase activity|ferrous iron binding|ferric iron binding|oxidoreductase activity|enzyme binding|iron chaperone activity|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,1.6,24.4,10,1.3,15.5,1.5,38.9,38.9,0.00161,0,1,1.2,2.2
ENSMUSG00000002718,CSE1L,chromosome segregation 1-like (S. cerevisiae),nucleus|cytoplasm|membrane|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|,protein binding|Ran GTPase binding|,9,1.6,15.4,8,1.3,24.3,1.5,38.7,38.7,0.00165,0,1,1,2.3
ENSMUSG00000006315,TMEM147,transmembrane protein 147,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.8,19,10,0.8,19.1,0.8,37.8,37.8,0.00175,0,1,0.6,1.2
ENSMUSG00000024392,BAG6,BCL2-associated athanogene 6,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytosol|BAT3 complex|,kidney development|immune system process|antigen processing and presentation of peptide antigen via MHC class I|ubiquitin-dependent protein catabolic process|transport|apoptotic process|synaptonemal complex assembly|spermatogenesis|brain development|embryo development|chromatin modification|internal peptidyl-lysine acetylation|cell differentiation|lung development|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|regulation of apoptotic process|regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of proteolysis|protein stabilization|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|tail-anchored membrane protein insertion into ER membrane|,protein binding|Hsp70 protein binding|polyubiquitin binding|ribosome binding|proteasome binding|,10,0.7,14.5,10,0.7,23.1,0.7,37.1,37.1,0.00184,0,1,0.5,1.1
ENSMUSG00000030105,ARL8B,ADP-ribosylation factor-like 8B,intracellular|cytoplasm|lysosome|endosome|cytoskeleton|membrane|membrane|midbody|spindle midzone|extracellular vesicular exosome|,cell cycle|chromosome segregation|mitotic nuclear division|small GTPase mediated signal transduction|cell division|,nucleotide binding|GTP binding|GDP binding|alpha-tubulin binding|beta-tubulin binding|,9,0.8,27.8,10,0.5,11.3,0.7,37,37,0.00184,0,1,0.5,1
ENSMUSG00000022841,AP2M1,"adaptor-related protein complex 2, mu 1 subunit",mitochondrion|plasma membrane|coated pit|membrane|clathrin adaptor complex|secretory granule|extracellular vesicular exosome|,transport|intracellular protein transport|endocytosis|protein transport|vesicle-mediated transport|,lipid binding|,10,1,17.9,10,1,19.2,1,36.7,36.7,0.0019,0,1,0.7,1.6
ENSMUSG00000035311,GNPTAB,"N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits",Golgi membrane|cell|nucleus|Golgi apparatus|membrane|integral component of membrane|,lysosome organization|protein secretion|cell differentiation|carbohydrate phosphorylation|carbohydrate phosphorylation|,"UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity|calcium ion binding|transcription factor binding|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,1.3,30.5,10,0.8,7.74,1.1,36.1,36.1,0.002,0,1,0.7,1.8
ENSMUSG00000002105,SLC39A13,"solute carrier family 39 (metal ion transporter), member 13",Golgi apparatus|Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|,transport|ion transport|zinc ion transport|cellular zinc ion homeostasis|cellular zinc ion homeostasis|metal ion transport|transmembrane transport|connective tissue development|connective tissue development|zinc ion transmembrane transport|zinc ion transmembrane transport|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|zinc ion transmembrane transporter activity|protein homodimerization activity|metal ion transmembrane transporter activity|,10,-0.7,19.1,10,-1,17.8,-0.9,35.8,-35.8,0.00211,0,1,-1.3,-0.6
ENSMUSG00000022568,SCRIB,scribbled homolog (Drosophila),cell|cytoplasm|plasma membrane|plasma membrane|cell-cell junction|cell-cell adherens junction|membrane|basolateral plasma membrane|cell junction|cell leading edge|Scrib-APC-beta-catenin complex|myelin sheath abaxonal region|presynaptic membrane|cell projection|postsynaptic membrane|extracellular vesicular exosome|,neural tube closure|neural tube closure|positive regulation of receptor recycling|auditory receptor cell morphogenesis|multicellular organismal development|asymmetric protein localization|cell proliferation|synaptic vesicle targeting|morphogenesis of embryonic epithelium|single organismal cell-cell adhesion|cell migration|cell migration|cochlear nucleus development|cell differentiation|activation of Rac GTPase activity|establishment of apical/basal cell polarity|wound healing|positive regulation of apoptotic process|astrocyte cell migration|negative regulation of mitotic cell cycle|synaptic vesicle endocytosis|positive chemotaxis|positive chemotaxis|auditory receptor cell stereocilium organization|apoptotic process involved in morphogenesis|mammary gland duct morphogenesis|protein localization to adherens junction|,protein binding|,10,1,12,10,1,23.7,1,35.3,35.3,0.00217,0,1,0.8,1.5
ENSMUSG00000034343,UBE2F,ubiquitin-conjugating enzyme E2F (putative),cellular_component|,protein neddylation|protein neddylation|,"nucleotide binding|ATP binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|NEDD8 ligase activity|NEDD8 ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1,3.59,10,0.7,32.1,0.7,34.7,34.7,0.00232,0,1,0.5,1.2
ENSMUSG00000056131,PGM3,phosphoglucomutase 3,cytosol|,carbohydrate metabolic process|UDP-N-acetylglucosamine biosynthetic process|spermatogenesis|embryo development|glucose 1-phosphate metabolic process|hemopoiesis|,"magnesium ion binding|phosphoacetylglucosamine mutase activity|phosphoacetylglucosamine mutase activity|phosphoglucomutase activity|isomerase activity|intramolecular transferase activity, phosphotransferases|metal ion binding|",10,2.1,24.1,10,0.9,14,0.9,34.6,34.6,0.00237,0,1,0.5,2.6
ENSMUSG00000005204,SENP3,SUMO/sentrin specific peptidase 3,nucleus|nucleolus|nucleolus|cytoplasm|MLL1 complex|,proteolysis|protein metabolic process|,ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.7,24.9,10,0.7,8.8,0.7,33.3,33.3,0.00275,0,1,0.3,2
ENSMUSG00000034932,MRPL54,mitochondrial ribosomal protein L54,mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,poly(A) RNA binding|,10,1.1,10.3,10,0.9,23.5,1,32.8,32.8,0.00296,0,1,0.7,1.4
ENSMUSG00000040414,SLC25A28,"solute carrier family 25, member 28",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|ion transport|iron ion homeostasis|,None,10,0.5,13.4,10,0.6,19.8,0.6,32.7,32.7,0.00299,0,1,0.4,0.9
ENSMUSG00000039230,TBCD,tubulin-specific chaperone d,cellular_component|cytoplasm|plasma membrane|tight junction|membrane|cell junction|,protein folding|post-chaperonin tubulin folding pathway|negative regulation of microtubule polymerization|positive regulation of GTPase activity|,GTPase activator activity|beta-tubulin binding|,10,0.9,23.6,10,1.1,9.17,1,32.1,32.1,0.00329,0,1,0.6,1.4
ENSMUSG00000042406,ATF4,activating transcription factor 4,intracellular|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|membrane|dendrite membrane|,"gluconeogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|gamma-aminobutyric acid signaling pathway|circadian regulation of gene expression|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|negative regulation of potassium ion transport|positive regulation of neuron apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|",core promoter sequence-specific DNA binding|DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein C-terminus binding|sequence-specific DNA binding|,10,0.7,8.06,10,1.6,27.4,0.6,31.9,31.9,0.00341,0,1,0.4,2.1
ENSMUSG00000027248,PDIA3,protein disulfide isomerase associated 3,nucleus|endoplasmic reticulum|endoplasmic reticulum|smooth endoplasmic reticulum|cell surface|cell surface|extracellular vesicular exosome|,protein folding|response to endoplasmic reticulum stress|cell redox homeostasis|positive regulation of extrinsic apoptotic signaling pathway|,protein disulfide isomerase activity|protein binding|isomerase activity|poly(A) RNA binding|,10,0.7,10.8,10,0.6,21.1,0.7,31.6,31.6,0.00366,0,1,0.5,1.1
ENSMUSG00000030220,ARHGDIB,"Rho, GDP dissociation inhibitor (GDI) beta",cytoplasm|extracellular vesicular exosome|,None,Rho GDP-dissociation inhibitor activity|GTPase activator activity|,10,-1.1,26.7,10,-0.4,5.63,-0.4,31.3,-31.3,0.00389,0,1,-1.3,-0.3
ENSMUSG00000021832,PSMC6,"proteasome (prosome, macropain) 26S subunit, ATPase, 6",proteasome complex|nucleus|cytoplasm|membrane|inclusion body|proteasome accessory complex|cytosolic proteasome complex|extracellular vesicular exosome|,protein catabolic process|positive regulation of inclusion body assembly|,nucleotide binding|ATP binding|hydrolase activity|,6,-0.9,10.6,6,1.6,31.3,1.5,31.1,31.1,0.004,0,1,0.9,2.8
ENSMUSG00000034254,AGPAT1,"1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)",endoplasmic reticulum|membrane|membrane|integral component of membrane|,positive regulation of cytokine production|lipid metabolic process|phosphatidic acid biosynthetic process|phosphatidic acid biosynthetic process|metabolic process|phospholipid biosynthetic process|,"1-acylglycerol-3-phosphate O-acyltransferase activity|1-acylglycerol-3-phosphate O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.6,12.5,10,0.9,19.1,0.7,30.5,30.5,0.00451,0,1,0.4,1.1
ENSMUSG00000036315,ZNRD1,"zinc ribbon domain containing, 1",nucleus|DNA-directed RNA polymerase I complex|,"transcription, DNA-templated|termination of RNA polymerase I transcription|",RNA polymerase I activity|nucleic acid binding|DNA-directed RNA polymerase activity|zinc ion binding|metal ion binding|,9,1,4.09,9,2.1,28.9,1.9,30.2,30.2,0.00475,0,0,1.2,3.7
ENSMUSG00000020671,RAB10,"RAB10, member RAS oncogene family",intracellular|cell|endosome|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|Golgi apparatus|trans-Golgi network|plasma membrane|membrane|cytoplasmic vesicle|insulin-responsive compartment|cell projection|perinuclear region of cytoplasm|recycling endosome|extracellular vesicular exosome|endoplasmic reticulum tubular network|primary cilium|primary cilium|,GTP catabolic process|transport|intracellular protein transport|Golgi to plasma membrane transport|small GTPase mediated signal transduction|axonogenesis|protein transport|vesicle-mediated transport|endosomal transport|antigen processing and presentation|cellular response to insulin stimulus|establishment of neuroblast polarity|endoplasmic reticulum tubular network organization|protein localization to plasma membrane|establishment of protein localization to endoplasmic reticulum membrane|,nucleotide binding|GTPase activity|protein binding|GTP binding|GDP binding|myosin V binding|,10,0.9,18.3,10,1,12,1,29.7,29.7,0.00528,0,0,0.7,1.5
ENSMUSG00000069678,PCGF1,polycomb group ring finger 1,nucleus|PcG protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|histone H2A monoubiquitination|",protein C-terminus binding|zinc ion binding|metal ion binding|,10,0.6,12.1,10,0.6,18,0.6,29.7,29.7,0.00528,0,0,0.4,0.9
ENSMUSG00000042569,DHRS7B,dehydrogenase/reductase (SDR family) member 7B,endoplasmic reticulum|membrane|membrane|integral component of membrane|,biological_process|metabolic process|oxidation-reduction process|,"oxidoreductase activity|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|versicolorin reductase activity|ketoreductase activity|",10,1,19.4,10,0.7,11.3,0.9,29.6,29.6,0.00533,0,0,0.6,1.4
ENSMUSG00000036550,CNOT1,"CCR4-NOT transcription complex, subunit 1",cytoplasmic mRNA processing body|cytoplasmic mRNA processing body|extracellular space|nucleus|cytoplasm|peroxisomal membrane|membrane|CCR4-NOT complex|,"negative regulation of transcription from RNA polymerase II promoter|trophectodermal cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|multicellular organismal development|positive regulation of cytoplasmic mRNA processing body assembly|gene silencing by RNA|negative regulation of intracellular estrogen receptor signaling pathway|negative regulation of retinoic acid receptor signaling pathway|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|RNA phosphodiester bond hydrolysis, exonucleolytic|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|regulation of stem cell maintenance|regulation of stem cell maintenance|",poly(A)-specific ribonuclease activity|protein binding|estrogen receptor binding|retinoic acid receptor binding|poly(A) RNA binding|,9,-1.3,27.9,9,0.5,4.28,-1.2,29.4,-29.4,0.0056,0,0,-2,-0.6
ENSMUSG00000008668,RPS18,ribosomal protein S18,intracellular|nucleus|cytoplasm|cytosol|ribosome|small ribosomal subunit|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|ribosome biogenesis|,nucleic acid binding|RNA binding|structural constituent of ribosome|protein binding|rRNA binding|poly(A) RNA binding|,4,1.7,5.67,4,1.4,24.4,1.5,29.3,29.3,0.00571,0,0,1.2,2.8
ENSMUSG00000009927,RPS25,ribosomal protein S25,nucleus|nucleolus|cytoplasm|ribosome|small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,ribosomal small subunit assembly|,structural constituent of ribosome|poly(A) RNA binding|,8,1.2,14,8,1.6,16.4,1.4,29.1,29.1,0.00591,0,0,0.9,2.4
ENSMUSG00000022858,TRA2B,transformer 2 beta homolog (Drosophila),nucleus|,"regulation of alternative mRNA splicing, via spliceosome|mRNA splicing, via spliceosome|mRNA processing|RNA splicing|positive regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|poly(A) RNA binding|,10,0.8,17.7,10,0.5,12.8,0.7,28.8,28.8,0.0063,0,0,0.5,1.1
ENSMUSG00000024128,SBP,spermine binding protein,extracellular region|,biological_process|,molecular_function|,10,0.6,5.71,10,1.8,26.6,0.6,28.6,28.6,0.00655,0,0,0.4,2.4
ENSMUSG00000023977,UBR2,ubiquitin protein ligase E3 component n-recognin 2,ubiquitin ligase complex|chromatin|nucleus|plasma membrane|,chromatin silencing|ubiquitin-dependent protein catabolic process|male meiosis I|spermatogenesis|protein ubiquitination|protein catabolic process|negative regulation of TOR signaling|histone H2A ubiquitination|cellular response to leucine|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|leucine binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.6,16.7,10,-0.7,11.8,-0.7,28.1,-28.1,0.00727,0,0,-1,-0.4
ENSMUSG00000051396,HSPA14,heat shock protein 14,cytoplasm|cytosol|ribosome|membrane|,biological_process|,nucleotide binding|ATP binding|,10,1.3,11.2,10,1.3,16.9,1.3,27.7,27.7,0.00794,0,0,0.8,2
ENSMUSG00000030335,MRPL51,mitochondrial ribosomal protein L51,mitochondrion|mitochondrial ribosome|mitochondrial ribosome|ribosome|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,10,-0.5,4.99,9,1.7,28.4,1.6,27.5,27.5,0.00826,0,0,1,2.9
ENSMUSG00000027642,RPN2,ribophorin II,autophagic vacuole membrane|nucleus|endoplasmic reticulum|rough endoplasmic reticulum|oligosaccharyltransferase complex|membrane|membrane|integral component of membrane|,protein N-linked glycosylation|,"transferase activity|transferase activity, transferring glycosyl groups|ribosome binding|",10,1.1,13.3,9,0.9,14.7,1,27.4,27.4,0.00836,0,0,0.7,1.5
ENSMUSG00000032512,WDR48,WD repeat domain 48,nucleus|cytoplasm|lysosome|intracellular membrane-bounded organelle|,double-strand break repair via homologous recombination|cellular response to DNA damage stimulus|spermatogenesis|single fertilization|male gonad development|protein deubiquitination|multicellular organism growth|skin development|embryonic organ development|skeletal system morphogenesis|homeostasis of number of cells|positive regulation of epithelial cell proliferation|seminiferous tubule development|regulation of protein monoubiquitination|,molecular_function|,10,0.8,2.3,10,1.7,26.9,1.6,26.7,26.7,0.00968,0,0,0.5,2.7
ENSMUSG00000028790,KHDRBS1,"KH domain containing, RNA binding, signal transduction associated 1",nucleus|nucleus|cytoplasm|membrane|Grb2-Sos complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|cell surface receptor signaling pathway|cell surface receptor signaling pathway|positive regulation of signal transduction|positive regulation of signal transduction|negative regulation of transcription, DNA-templated|positive regulation of translational initiation|regulation of RNA export from nucleus|positive regulation of RNA export from nucleus|",RNA binding|RNA binding|SH3/SH2 adaptor activity|SH3/SH2 adaptor activity|protein binding|poly(A) binding|poly(U) RNA binding|SH3 domain binding|protein complex binding|poly(A) RNA binding|,10,-0.8,10.7,10,-0.8,16.1,-0.8,26.5,-26.5,0.00997,0,0,-1.4,-0.6
ENSMUSG00000052296,PPP6R1,"protein phosphatase 6, regulatory subunit 1",cytoplasm|,regulation of phosphoprotein phosphatase activity|,protein phosphatase binding|,10,0.9,13.3,10,0.6,13.9,0.7,26.5,26.5,0.00997,0,0,0.4,1.1
ENSMUSG00000031938,4931406C07RIK,RIKEN cDNA 4931406C07 gene,nucleus|extracellular vesicular exosome|,metabolic process|,"nuclease activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|",10,-1.6,23.7,10,-0.8,5.7,-1.4,26.3,-26.3,0.0105,0,0,-2.6,-0.6
ENSMUSG00000040521,TSFM,"Ts translation elongation factor, mitochondrial",intracellular|nucleus|mitochondrion|mitochondrion|,translation|translational elongation|,translation elongation factor activity|poly(A) RNA binding|,10,0.7,3.62,10,1,23.4,1,26,26,0.0112,0,0,0.7,1.5
ENSMUSG00000071072,PTGES3,prostaglandin E synthase 3 (cytosolic),nucleus|telomerase holoenzyme complex|cytoplasm|actin filament|neuron projection|neuronal cell body|intracellular membrane-bounded organelle|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,prostaglandin biosynthetic process|prostaglandin biosynthetic process|glycogen biosynthetic process|RNA-dependent DNA replication|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|cell proliferation|positive regulation of gene expression|sensory perception of pain|glucocorticoid receptor signaling pathway|skin development|lung saccule development|negative regulation of cell death|chaperone cofactor-dependent protein refolding|DNA biosynthetic process|,p53 binding|telomerase activity|isomerase activity|enzyme binding|prostaglandin-E synthase activity|unfolded protein binding|Hsp90 protein binding|,10,-2,22.5,10,1,20,0.8,25.9,25.9,0.0115,0,0,-2.9,2
ENSMUSG00000013160,ATP6V0D1,"ATPase, H+ transporting, lysosomal V0 subunit D1","lysosomal membrane|early endosome|centrosome|synaptic vesicle|membrane|apical plasma membrane|vacuolar proton-transporting V-type ATPase complex|proton-transporting V-type ATPase, V0 domain|neuron projection|protein complex|axon terminus|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|cell projection organization|hydrogen ion transmembrane transport|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrogen ion transmembrane transporter activity|protein complex binding|",10,0.8,5.24,10,1.9,23.8,1.7,25.4,25.4,0.0129,0,0,0.6,2.8
ENSMUSG00000034432,COPS8,"COP9 (constitutive photomorphogenic) homolog, subunit 8 (Arabidopsis thaliana)",nucleus|nucleus|cytoplasm|COP9 signalosome|COP9 signalosome|perinuclear region of cytoplasm|extracellular vesicular exosome|,activation of NF-kappaB-inducing kinase activity|negative regulation of cell proliferation|cullin deneddylation|,protein binding|,10,0.6,14,10,0.6,11.6,0.6,25.2,25.2,0.0134,0,0,0.4,1.1
ENSMUSG00000025894,AASDHPPT,aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase,cytoplasm|extracellular vesicular exosome|,macromolecule biosynthetic process|,magnesium ion binding|cardiolipin synthase activity|holo-[acyl-carrier-protein] synthase activity|transferase activity|UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity|GDP-mannose:serine-protein mannose-1-phosphotransferase activity|archaetidylserine synthase activity|metal ion binding|,8,-2.3,25.6,7,-0.8,2.33,-2.3,25,-25,0.0141,0,0,-4,-1.8
ENSMUSG00000030216,WBP11,WW domain binding protein 11,nucleus|nucleus|cytoplasm|cytoplasm|nuclear speck|,rRNA processing|RNA processing|mRNA processing|RNA splicing|regulation of catalytic activity|,protein binding|protein phosphatase type 1 regulator activity|poly(A) RNA binding|WW domain binding|,10,0.7,4.48,10,1.9,24.6,1.7,25,25,0.0141,0,0,0.5,2.8
ENSMUSG00000042541,SHFM1,split hand/foot malformation (ectrodactyly) type 1,proteasome complex|proteasome complex|nucleus|integrator complex|,double-strand break repair via homologous recombination|proteolysis|proteolysis|,protein binding|peptidase activity|,10,0.3,2.34,10,1.6,26.8,1.5,24.8,24.8,0.0148,0,0,0.9,2.9
ENSMUSG00000030707,CORO1A,"coronin, actin binding protein 1A",immunological synapse|phagocytic cup|phagocytic cup|cytoplasm|cytoskeleton|actin filament|plasma membrane|plasma membrane|plasma membrane|cell-cell junction|actin cytoskeleton|membrane|membrane|lamellipodium|lamellipodium|cortical actin cytoskeleton|cortical actin cytoskeleton|cell leading edge|cytoplasmic vesicle|protein complex|phagocytic vesicle|phagocytic vesicle|extracellular vesicular exosome|,phagolysosome assembly|phagolysosome assembly|calcium ion transport|phagocytosis|actin filament organization|regulation of actin polymerization or depolymerization|regulation of cell shape|cell migration|actin cytoskeleton organization|positive regulation of cell migration|leukocyte chemotaxis|regulation of actin filament polymerization|cell-substrate adhesion|uropod organization|response to cytokine|positive regulation of T cell proliferation|T cell homeostasis|homeostasis of number of cells within a tissue|positive regulation of T cell activation|positive chemotaxis|positive chemotaxis|negative regulation of actin nucleation|negative regulation of actin nucleation|cellular response to interleukin-4|,actin binding|protein binding|protein C-terminus binding|cytoskeletal protein binding|identical protein binding|protein homodimerization activity|phosphatidylinositol 3-kinase binding|poly(A) RNA binding|actin filament binding|actin filament binding|,10,0.9,6.54,10,0.7,19.1,0.8,24.6,24.6,0.0155,0,0,0.5,1.3
ENSMUSG00000056167,CNOT10,"CCR4-NOT transcription complex, subunit 10",nucleus|cytoplasm|membrane|CCR4-NOT complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|biological_process|gene silencing by RNA|",molecular_function|,10,-1.6,22.9,8,-0.7,5.32,-1.5,24.5,-24.5,0.0158,0,0,-2.7,-0.6
ENSMUSG00000042055,WDR11,WD repeat domain 11,nucleus|cytoplasm|lysosomal membrane|cilium|membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,14.3,10,0.8,10.6,0.7,24.4,24.4,0.0162,0,0,0.5,1.2
ENSMUSG00000050211,PLA2G4E,"phospholipase A2, group IVE",cytoplasm|lysosome|membrane|,lipid metabolic process|metabolic process|phospholipid catabolic process|lipid catabolic process|,phospholipase activity|phospholipase A2 activity|hydrolase activity|metal ion binding|,10,-1.4,26.5,10,0,0,-1.4,23.6,-23.6,0.0194,0,0,-2.8,-0.5
ENSMUSG00000040877,WDR25,WD repeat domain 25,cellular_component|,biological_process|,molecular_function|,10,1.3,13.6,10,0.8,13,1.2,23.6,23.6,0.0194,0,0,0.8,1.8
ENSMUSG00000030007,CCT7,"chaperonin containing Tcp1, subunit 7 (eta)",zona pellucida receptor complex|cytoplasm|mitochondrion|chaperonin-containing T-complex|microtubule|cell body|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|,nucleotide binding|protein binding|ATP binding|identical protein binding|unfolded protein binding|,8,1.5,12.2,8,0.7,14.8,0.8,23.5,23.5,0.0199,0,0,0.5,1.9
ENSMUSG00000021546,HNRNPK,heterogeneous nuclear ribonucleoprotein K,nuclear chromatin|nucleus|spliceosomal complex|cytoplasm|membrane|virion|viral nucleocapsid|cell junction|ribonucleoprotein complex|cell projection|extracellular vesicular exosome|catalytic step 2 spliceosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|mRNA processing|RNA splicing|regulation of low-density lipoprotein particle clearance|positive regulation of low-density lipoprotein particle receptor biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of receptor-mediated endocytosis|regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter|regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|single-stranded DNA binding|RNA binding|protein binding|poly(A) RNA binding|,7,-0.7,10.7,6,-0.9,13.3,-0.7,23.4,-23.4,0.0204,0,0,-1.4,-0.5
ENSMUSG00000021917,SPCS1,signal peptidase complex subunit 1 homolog (S. cerevisiae),endoplasmic reticulum|signal peptidase complex|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|integral component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,signal peptide processing|proteolysis|biological_process|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ribosome binding|,10,2.1,24.6,9,0.5,2.46,1.9,23.2,23.2,0.0213,0,0,0.4,3.6
ENSMUSG00000053317,SEC61B,Sec61 beta subunit,endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|,"protein import into nucleus, translocation|transport|protein transport|ER-associated ubiquitin-dependent protein catabolic process|retrograde protein transport, ER to cytosol|",ribosome binding|poly(A) RNA binding|epidermal growth factor binding|,10,1.2,14.1,10,0.6,11.9,0.6,23,23,0.0223,0,0,0.4,1.4
ENSMUSG00000040351,ANKIB1,ankyrin repeat and IBR domain containing 1,cellular_component|,biological_process|,zinc ion binding|metal ion binding|,10,0.5,5.33,10,2.2,24,2.1,22.8,22.8,0.0232,0,0,1,4
ENSMUSG00000021427,SSR1,"signal sequence receptor, alpha",endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,None,None,10,-0.6,12.7,10,-0.6,10.2,-0.6,22.6,-22.6,0.0243,0,0,-1,-0.4
ENSMUSG00000031422,MORF4L2,mortality factor 4 like 2,nucleus|,"DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|chromatin modification|regulation of growth|",None,10,0.7,13.9,10,1,9.59,0.9,22.5,22.5,0.0249,0,0,0.5,1.3
ENSMUSG00000078578,UBE2D3,ubiquitin-conjugating enzyme E2D 3,cellular_component|endosome|plasma membrane|membrane|,protein polyubiquitination|DNA repair|ubiquitin-dependent protein catabolic process|protein monoubiquitination|apoptotic process|cellular response to DNA damage stimulus|protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|protein K48-linked ubiquitination|protein K11-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|,10,2.1,23.7,10,0.3,2.41,0.5,22.3,22.3,0.026,0,0,0.4,3.6
ENSMUSG00000024436,MRPS18B,mitochondrial ribosomal protein S18B,intracellular|nucleus|mitochondrion|mitochondrion|ribosome|cell junction|ribonucleoprotein complex|,translation|,structural constituent of ribosome|,10,0.7,8.76,10,1,14.6,0.8,22.3,22.3,0.026,0,0,0.6,1.4
ENSMUSG00000022771,PPIL2,peptidylprolyl isomerase (cyclophilin)-like 2,nucleus|,protein polyubiquitination|protein peptidyl-prolyl isomerization|protein folding|protein ubiquitination|,peptidyl-prolyl cis-trans isomerase activity|ubiquitin-protein transferase activity|isomerase activity|ubiquitin-ubiquitin ligase activity|,10,0.4,1.9,9,0.8,21.2,0.7,22.2,22.2,0.0267,0,0,0.5,1.3
ENSMUSG00000021322,AOAH,acyloxyacyl hydrolase,extracellular region|,lipid metabolic process|lipopolysaccharide metabolic process|negative regulation of inflammatory response|,"hydrolase activity|hydrolase activity, acting on ester bonds|acyloxyacyl hydrolase activity|",10,0.2,0.583,10,2.1,24.8,2.1,22.2,22.2,0.0267,0,0,1.3,4
ENSMUSG00000047098,RNF31,ring finger protein 31,cytoplasm|cytosol|cytoplasmic side of plasma membrane|CD40 receptor complex|LUBAC complex|,protein polyubiquitination|protein ubiquitination|CD40 signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|T cell receptor signaling pathway|positive regulation of NF-kappaB transcription factor activity|negative regulation of necroptotic process|protein linear polyubiquitination|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",8,-0.7,13.2,7,-0.7,9.24,-0.7,22,-22,0.0281,0,0,-1.2,-0.4
ENSMUSG00000036449,LCN8,lipocalin 8,cellular_component|extracellular region|,transport|response to hormone|,molecular_function|,10,-1.4,24.7,10,0.4,2.11,-1.4,21.9,-21.9,0.0288,0,0,-2.9,-0.5
ENSMUSG00000039740,ALG2,"asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase)",nucleus|cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|perinuclear region of cytoplasm|,dolichol-linked oligosaccharide biosynthetic process|biosynthetic process|protein glycosylation in endoplasmic reticulum|response to calcium ion|mannosylation|,"alpha-1,3-mannosyltransferase activity|GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|glycolipid 6-alpha-mannosyltransferase activity|protein anchor|protein heterodimerization activity|protein N-terminus binding|calcium-dependent protein binding|",8,-1.1,23.7,7,0.4,1.13,-1.1,21.9,-21.9,0.0288,0,0,-1.9,-0.7
ENSMUSG00000098134,RNF113A2,ring finger protein 113A2,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,1.6,13.9,10,0.7,9.33,0.6,21.8,21.8,0.0294,0,0,0.4,2
ENSMUSG00000025203,SCD2,stearoyl-Coenzyme A desaturase 2,endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|oxidation-reduction process|,"stearoyl-CoA 9-desaturase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water|",6,0.2,0.378,6,-1.3,24.1,-1.2,21.8,-21.8,0.0294,0,0,-2,-0.8
ENSMUSG00000027341,TMEM230,transmembrane protein 230,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.5,9.67,10,-0.6,12.5,-0.5,21.4,-21.4,0.0326,0,0,-0.9,-0.4
ENSMUSG00000024608,RPS14,ribosomal protein S14,nucleolus|mitochondrion|ribosome|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,ribosomal small subunit assembly|negative regulation of transcription from RNA polymerase II promoter|translation|regulation of translation|erythrocyte differentiation|,structural constituent of ribosome|poly(A) RNA binding|translation regulator activity|mRNA 5'-UTR binding|,6,-1.2,18.3,6,-0.9,3.83,-1,21.3,-21.3,0.0334,0,0,-2,-0.8
ENSMUSG00000034108,CCS,copper chaperone for superoxide dismutase,nucleus|cytoplasm|cytoplasm|,superoxide metabolic process|removal of superoxide radicals|metal ion transport|positive regulation of oxidoreductase activity|oxidation-reduction process|,superoxide dismutase activity|copper ion binding|zinc ion binding|enzyme binding|metal ion binding|,8,-1.2,12.4,6,1.4,13.4,1.3,21.1,21.1,0.0349,0,0,0.9,1.9
ENSMUSG00000025544,TM9SF2,transmembrane 9 superfamily member 2,endosome|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,9,1.3,14.8,8,1,7.01,1.2,20.9,20.9,0.0366,0,0,0.7,2
ENSMUSG00000052557,GAN,giant axonal neuropathy,cytoplasm|cytoskeleton|Cul3-RING ubiquitin ligase complex|,cytoskeleton organization|cell death|protein ubiquitination|,None,10,-0.4,2.46,10,1.8,24.2,1.8,20.8,20.8,0.0374,0,0,0.8,3
ENSMUSG00000025532,CRCP,calcitonin gene-related peptide-receptor component protein,acrosomal vesicle|nucleus|plasma membrane|DNA polymerase III complex|membrane|,"immune system process|transcription, DNA-templated|transcription from RNA polymerase III promoter|inflammatory response|neuropeptide signaling pathway|cellular metabolic process|innate immune response|defense response to virus|",nucleotide binding|calcitonin gene-related polypeptide receptor activity|catalytic activity|DNA-directed RNA polymerase activity|,10,0.9,12.5,10,0.8,8.9,0.8,20.8,20.8,0.0374,0,0,0.5,1.3
ENSMUSG00000039148,SART1,squamous cell carcinoma antigen recognized by T cells 1,nucleus|nucleoplasm|spliceosomal complex|Golgi apparatus|Cajal body|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|positive regulation of cytotoxic T cell differentiation|,poly(A) RNA binding|,10,1.2,9.59,10,0.8,12.7,1,20.7,20.7,0.0383,0,0,0.6,1.7
ENSMUSG00000021288,KLC1,kinesin light chain 1,intracellular|cell|cytoplasm|cytosol|cytoskeleton|kinesin complex|kinesin complex|microtubule|membrane|axon|axon|growth cone|cytoplasmic vesicle|vesicle|ciliary rootlet|ciliary rootlet|cell projection|neuron projection|neuron projection|neuronal cell body|membrane-bounded organelle|,intracellular protein transport|microtubule-based movement|axon cargo transport|protein localization to synapse|stress granule disassembly|,microtubule motor activity|protein binding|tubulin binding|,10,0.4,3.64,10,0.9,19.6,0.8,20.6,20.6,0.0391,0,0,0.4,1.3
ENSMUSG00000020521,RNFT1,"ring finger protein, transmembrane 1",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-2,22.2,10,0.2,2.06,-1.9,20.6,-20.6,0.0391,0,0,-4,-1.5
ENSMUSG00000079555,HAUS3,"HAUS augmin-like complex, subunit 3",cytoplasm|centrosome|cytoskeleton|microtubule|HAUS complex|,cell cycle|mitotic nuclear division|spindle assembly|centrosome organization|cell division|,None,9,-1.4,23.1,8,1,2.21,-1.4,20.4,-20.4,0.041,0,0,-2,-0.5
ENSMUSG00000043207,ZMPSTE24,"zinc metallopeptidase, STE24",nucleus|endoplasmic reticulum|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,proteolysis|nuclear envelope organization|nuclear envelope organization|prenylated protein catabolic process|CAAX-box protein processing|,metalloendopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,-0.2,0.232,10,2.2,23.9,2.2,20.4,20.4,0.041,0,0,1.6,4
ENSMUSG00000029177,CENPA,centromere protein A,"chromosome, centromeric region|chromosome, centromeric region|kinetochore|condensed nuclear chromosome kinetochore|condensed nuclear chromosome, centromeric region|nucleosome|condensed chromosome inner kinetochore|nucleus|chromosome|","establishment of mitotic spindle orientation|kinetochore assembly|protein localization to chromosome, centromeric region|",DNA binding|protein heterodimerization activity|,10,1.2,13.4,10,1,7.34,1,20.3,20.3,0.0421,0,0,0.6,1.8
ENSMUSG00000024371,C2,complement component 2 (within H-2S),extracellular region|,"immune system process|proteolysis|complement activation|complement activation, classical pathway|innate immune response|positive regulation of apoptotic cell clearance|",catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,6,-1.3,22.9,6,0,0,-1.3,20.2,-20.2,0.043,0,0,-2,-0.6
ENSMUSG00000029407,USO1,USO1 vesicle docking factor,Golgi membrane|nucleolus|cytoplasm|endoplasmic reticulum|Golgi apparatus|Golgi stack|cytosol|ER to Golgi transport vesicle membrane|membrane|membrane|perinuclear region of cytoplasm|,transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|transcytosis|transcytosis|Golgi vesicle transport|Golgi vesicle docking|vesicle fusion with Golgi apparatus|membrane fusion|membrane fusion|,protein binding|protein transporter activity|poly(A) RNA binding|,10,-1.1,14.8,10,-0.6,6.13,-1,20,-20,0.0446,0,0,-1.7,-0.3
ENSMUSG00000026483,FAM129A,"family with sequence similarity 129, member A",cytoplasm|plasma membrane|membrane|extracellular vesicular exosome|,negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|regulation of translation|response to stress|response to endoplasmic reticulum stress|positive regulation of translation|,molecular_function|,10,0.5,0.873,10,1.7,22.1,1.7,20,20,0.0446,0,0,0.6,3
ENSMUSG00000044681,CNPY1,canopy 1 homolog (zebrafish),cellular_component|,biological_process|,molecular_function|,10,-1.3,20.8,10,0,0,-1.6,19.9,-19.9,0.0457,0,0,-3,-1
ENSMUSG00000019039,DALRD3,DALR anticodon binding domain containing 3,cellular_component|,tRNA aminoacylation for protein translation|arginyl-tRNA aminoacylation|biological_process|,nucleotide binding|aminoacyl-tRNA ligase activity|arginine-tRNA ligase activity|ATP binding|,10,-1.8,22.6,10,-0.3,1.23,-1.8,19.8,-19.8,0.0469,0,0,-3,-1.2
ENSMUSG00000045302,PREB,prolactin regulatory element binding,nucleus|endoplasmic reticulum|membrane|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transport|protein transport|vesicle-mediated transport|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|,8,-0.9,10.9,8,-1.2,10,-1,19.7,-19.7,0.0479,0,0,-1.8,-0.7
ENSMUSG00000034311,KIF4,kinesin family member 4,nucleus|chromosome|cytoplasm|cytoskeleton|kinesin complex|microtubule|membrane|midbody|,microtubule-based movement|,nucleotide binding|DNA binding|microtubule motor activity|ATP binding|microtubule binding|,9,-1.1,21.2,6,-0.3,0.479,-1,19.5,-19.5,0.0503,0,0,-2,-0.7
ENSMUSG00000022789,DNM1L,dynamin 1-like,cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane|peroxisome|Golgi apparatus|cytosol|cytosol|microtubule|coated pit|membrane|membrane|cell junction|cytoplasmic vesicle|intracellular membrane-bounded organelle|protein complex|synapse|perinuclear region of cytoplasm|,mitochondrial fission|mitochondrial fission|release of cytochrome c from mitochondria|dynamin polymerization involved in mitochondrial fission|GTP catabolic process|endocytosis|regulation of mitochondrion organization|programmed cell death|peroxisome fission|regulation of protein oligomerization|positive regulation of apoptotic process|mitochondrial fragmentation involved in apoptotic process|positive regulation of protein secretion|protein homotetramerization|membrane fusion|necroptotic process|necroptotic process|mitochondrion morphogenesis|protein localization to mitochondrion|membrane fission involved in mitochondrial fission|positive regulation of release of cytochrome c from mitochondria|regulation of peroxisome organization|positive regulation of intrinsic apoptotic signaling pathway|,nucleotide binding|GTPase activity|protein binding|GTP binding|lipid binding|hydrolase activity|ubiquitin protein ligase binding|identical protein binding|protein homodimerization activity|,10,0.9,13.2,10,0.7,6.69,0.8,19.4,19.4,0.0515,0,0,0.5,1.3
ENSMUSG00000020114,CAND1,cullin associated and neddylation disassociated 1,ubiquitin ligase complex|nucleus|cytoplasm|membrane|cullin-RING ubiquitin ligase complex|intracellular membrane-bounded organelle|extracellular vesicular exosome|,"SCF complex assembly|protein ubiquitination|cell differentiation|negative regulation of catalytic activity|positive regulation of transcription, DNA-templated|positive regulation of RNA polymerase II transcriptional preinitiation complex assembly|",protein binding|TBP-class protein binding|,10,1.5,11.7,9,0.8,9.64,0.8,19.3,19.3,0.0527,0,0,0.5,1.9
ENSMUSG00000029920,SMARCAD1,"SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1",heterochromatin|nucleus|nucleus|chromosome|site of double-strand break|nuclear replication fork|,regulation of DNA recombination|DNA double-strand break processing|DNA repair|cellular response to DNA damage stimulus|chromatin modification|ATP-dependent chromatin remodeling|chromosome separation|histone H3 deacetylation|histone H4 deacetylation|,nucleotide binding|DNA binding|helicase activity|ATP binding|hydrolase activity|,10,-0.5,8.61,10,-0.5,11.1,-0.5,19.3,-19.3,0.0527,0,0,-0.8,-0.3
ENSMUSG00000031839,HSBP1,heat shock factor binding protein 1,nucleus|cytoskeleton|,muscle contraction|endodermal cell differentiation|,molecular_function|,10,0.6,11.2,10,0.5,8.53,0.5,19.3,19.3,0.0527,0,0,0.3,0.9
ENSMUSG00000078515,DDI2,DNA-damage inducible protein 2,cellular_component|,proteolysis|,aspartic-type endopeptidase activity|,10,0.6,5.23,10,0.8,15.3,0.7,19.2,19.2,0.054,0,0,0.4,1.2
ENSMUSG00000015127,UNKL,unkempt-like (Drosophila),cellular_component|nucleus|cytoplasm|,biological_process|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.391,10,2.2,22.4,2.2,19.1,19.1,0.0552,0,0,1.7,4
ENSMUSG00000063801,AP3S2,"adaptor-related protein complex 3, sigma 2 subunit",intracellular|cell|Golgi apparatus|trans-Golgi network|membrane|membrane coat|AP-3 adaptor complex|cytoplasmic vesicle|,transport|intracellular protein transport|anterograde axon cargo transport|protein transport|vesicle-mediated transport|anterograde synaptic vesicle transport|,protein transporter activity|,10,-0.1,0.363,10,2.2,22.7,2.2,19.1,19.1,0.0552,0,0,1.7,4
ENSMUSG00000033906,ZDHHC15,"zinc finger, DHHC domain containing 15",Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,synaptic vesicle maturation|synaptic vesicle maturation|protein palmitoylation|protein palmitoylation|establishment of protein localization|,"zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,-2.2,22,10,0.6,2.92,-2.2,18.9,-18.9,0.0579,0,0,-4,-1.8
ENSMUSG00000032217,RNF111,ring finger 111,nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|protein complex|,"protein polyubiquitination|protein polyubiquitination|protein polyubiquitination|multicellular organismal development|pattern specification process|protein ubiquitination|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|ubiquitin-dependent SMAD protein catabolic process|ubiquitin-dependent SMAD protein catabolic process|positive regulation of protein ubiquitination|positive regulation of protein ubiquitination|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|","ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO polymer binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|SMAD binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.6,4.91,10,0.8,14.3,0.8,18.6,18.6,0.0606,0,0,0.5,1.3
ENSMUSG00000031959,WDR59,WD repeat domain 59,cellular_component|,biological_process|,molecular_function|,10,0.6,10.9,10,0.4,8.48,0.5,18.6,18.6,0.0606,0,0,0.3,0.9
ENSMUSG00000040260,DAAM2,dishevelled associated activator of morphogenesis 2,cellular_component|,determination of left/right symmetry|cellular component organization|actin cytoskeleton organization|,actin binding|Rho GTPase binding|,10,2.2,22.1,10,-0.3,1.39,2.2,18.6,18.6,0.0606,0,0,1.5,4
ENSMUSG00000032560,DNAJC13,"DnaJ (Hsp40) homolog, subfamily C, member 13",lysosomal membrane|membrane|extracellular vesicular exosome|,osteoblast differentiation|,molecular_function|,10,1,10.1,10,0.5,9.94,0.7,18.6,18.6,0.0606,0,0,0.4,1.3
ENSMUSG00000032382,SNX1,sorting nexin 1,cytoplasm|endosome|early endosome|Golgi apparatus|cytosol|endosome membrane|membrane|cytoplasmic membrane-bounded vesicle|retromer complex|early endosome membrane|intracellular membrane-bounded organelle|,"transport|intracellular protein transport|intracellular protein transport|protein transport|early endosome to Golgi transport|retrograde transport, endosome to Golgi|positive regulation of protein catabolic process|",lipid binding|phosphatidylinositol binding|phosphatidylinositol binding|,10,0.1,0.101,10,2.3,22,2.3,18.5,18.5,0.0614,0,0,1.8,4
ENSMUSG00000024260,SAP130,Sin3A associated protein,nucleus|STAGA complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|histone H3 acetylation|",transcription coactivator activity|histone acetyltransferase activity|protein binding|,10,-0.6,5.34,10,-0.7,13.7,-0.7,18.4,-18.4,0.0623,0,0,-1.2,-0.4
ENSMUSG00000071516,HIST1H2AI,"histone cluster 1, H2ai",nucleus|extracellular vesicular exosome|,biological_process|,None,9,0.8,10.4,9,1.3,9.69,1.1,18.4,18.4,0.0623,0,0,0.4,1.7
ENSMUSG00000021993,MIPEP,mitochondrial intermediate peptidase,mitochondrion|mitochondrion|,proteolysis|biological_process|,molecular_function|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,1.1,11.5,10,0.8,7.9,1,18.3,18.3,0.0629,0,0,0.6,1.6
ENSMUSG00000035227,SPCS2,signal peptidase complex subunit 2 homolog (S. cerevisiae),cellular_component|endoplasmic reticulum|signal peptidase complex|membrane|integral component of membrane|intracellular membrane-bounded organelle|,signal peptide processing|proteolysis|biological_process|,molecular_function|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,-1,7.39,10,-1.2,11.6,-1,18.3,-18.3,0.0629,0,0,-1.8,-0.7
ENSMUSG00000028343,ERP44,endoplasmic reticulum protein 44,endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endoplasmic reticulum-Golgi intermediate compartment|cell surface|cell surface|extracellular vesicular exosome|,protein folding|protein folding|response to unfolded protein|glycoprotein metabolic process|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|cell redox homeostasis|,protein disulfide isomerase activity|protein disulfide isomerase activity|protein binding|,10,0.6,10.9,10,0.7,7.76,0.6,18.3,18.3,0.0629,0,0,0.3,1
ENSMUSG00000021824,AP3M1,"adaptor-related protein complex 3, mu 1 subunit",intracellular|cell|lysosomal membrane|Golgi apparatus|membrane|clathrin adaptor complex|cytoplasmic vesicle|,transport|intracellular protein transport|anterograde axon cargo transport|protein transport|vesicle-mediated transport|anterograde synaptic vesicle transport|,Rab GTPase binding|,10,0.5,9.34,10,0.4,9.24,0.5,18.1,18.1,0.0644,0,0,0.3,0.8
ENSMUSG00000070426,RNF121,ring finger protein 121,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-1.3,20.8,10,0.1,0.0509,-1.3,17.9,-17.9,0.0656,0,0,-2,-0.4
ENSMUSG00000027291,VPS39,vacuolar protein sorting 39 (yeast),cytoplasm|lysosome|lysosomal membrane|endosome|membrane|HOPS complex|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,small GTPase regulator activity|protein binding|,10,1.2,13.2,10,0.7,5.96,1,17.7,17.7,0.0666,0,0,0.5,1.8
ENSMUSG00000018415,GID4,"GID complex subunit 4, VID24 homolog (S. cerevisiae)",cellular_component|,biological_process|,molecular_function|,10,0.8,8.25,10,0.8,9.72,0.8,17.6,17.6,0.0671,0,0,0.5,1.4
ENSMUSG00000027300,UBOX5,U box domain containing 5,nucleus|,protein polyubiquitination|protein ubiquitination|,ubiquitin-protein transferase activity|zinc ion binding|ubiquitin-ubiquitin ligase activity|metal ion binding|,5,1,14.5,5,1.3,3.69,1.2,17.5,17.5,0.0676,0,0,0.8,1.9
ENSMUSG00000028419,CHMP5,charged multivesicular body protein 5,intracellular|cell|nucleus|cytoplasm|endosome|membrane|extracellular vesicular exosome|,regulation of receptor recycling|transport|lysosome organization|endosome to lysosome transport|protein transport|,molecular_function|,10,-0.6,5.75,9,-1.9,15.7,-0.8,17.4,-17.4,0.0681,0,0,-2.5,-0.2
ENSMUSG00000029103,LRPAP1,low density lipoprotein receptor-related protein associated protein 1,extracellular region|cytoplasm|endoplasmic reticulum|plasma membrane|vesicle|rough endoplasmic reticulum lumen|,negative regulation of very-low-density lipoprotein particle clearance|negative regulation of protein binding|extracellular negative regulation of signal transduction|negative regulation of beta-amyloid clearance|negative regulation of receptor activity|,heparin binding|lipase binding|receptor antagonist activity|low-density lipoprotein particle receptor binding|low-density lipoprotein particle receptor binding|very-low-density lipoprotein particle receptor binding|,10,0.6,9.58,10,0.6,7.67,0.6,16.9,16.9,0.0705,0,0,0.3,1
ENSMUSG00000040710,ST8SIA4,"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,ganglioside biosynthetic process|protein glycosylation|N-glycan processing|oligosaccharide metabolic process|sialylation|sialylation|,"alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.7,4.82,10,0.5,12.6,0.6,16.8,16.8,0.071,0,0,0.3,1
ENSMUSG00000001998,AP4E1,"adaptor-related protein complex AP-4, epsilon 1",Golgi apparatus|trans-Golgi network|coated pit|membrane|membrane coat|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,None,10,0.4,1.83,10,-1.5,19.7,-1.5,16.7,-16.7,0.0717,0,0,-2.8,-1
ENSMUSG00000020435,OSBP2,oxysterol binding protein 2,cellular_component|membrane|,transport|lipid transport|biological_process|,lipid binding|cholesterol binding|,10,-0.6,2.64,10,1.6,19.8,1.6,16.6,16.6,0.0721,0,0,0.4,3
ENSMUSG00000026663,ATF6,activating transcription factor 6,nucleus|nucleus|endoplasmic reticulum|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|response to unfolded protein|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,1.7,6.98,10,0.5,10.8,0.5,16.5,16.5,0.0725,0,0,0.3,1.7
ENSMUSG00000049751,RPL36AL,ribosomal protein L36A-like,None,response to organic substance|response to retinoic acid|,None,10,0.8,11.5,9,0.6,5.35,0.7,15.9,15.9,0.0748,0,0,0.3,1.4
ENSMUSG00000015839,NFE2L2,"nuclear factor, erythroid derived 2, like 2",chromatin|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|centrosome|cytosol|cytosol|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|proteasomal ubiquitin-independent protein catabolic process|protein ubiquitination|positive regulation of blood coagulation|endoplasmic reticulum unfolded protein response|cellular response to oxidative stress|cellular response to oxidative stress|positive regulation of transcription from RNA polymerase II promoter in response to stress|positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of embryonic development|negative regulation of cell death|cellular response to hydrogen peroxide|cellular response to tumor necrosis factor|cellular response to laminar fluid shear stress|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|regulation of removal of superoxide radicals|negative regulation of endothelial cell apoptotic process|positive regulation of reactive oxygen species metabolic process|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II activating transcription factor binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|transcription cofactor binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein domain specific binding|sequence-specific DNA binding|,10,0.8,11.8,10,0.5,4.82,0.7,15.9,15.9,0.0748,0,0,0.4,1.2
ENSMUSG00000002763,PEX6,peroxisomal biogenesis factor 6,cytoplasm|peroxisome|peroxisomal membrane|cytosol|membrane|,"ATP catabolic process|protein targeting to peroxisome|peroxisome organization|protein import into peroxisome matrix, translocation|protein stabilization|","nucleotide binding|protein binding|ATP binding|protein C-terminus binding|ATPase activity|protein complex binding|ATPase activity, coupled|",10,0.5,7.27,10,0.5,8.43,0.5,15.3,15.3,0.0766,0,0,0.3,0.9
ENSMUSG00000034708,GRN,granulin,extracellular region|extracellular space|mitochondrion|cell surface|intracellular membrane-bounded organelle|extracellular vesicular exosome|,blastocyst hatching|embryo implantation|positive regulation of neuron projection development|response to estradiol|chondrocyte proliferation|synaptic vesicle endocytosis|positive regulation of epithelial cell proliferation|male mating behavior|positive regulation of dendritic spine development|neural precursor cell proliferation|,cytokine activity|poly(A) RNA binding|,10,0.6,12.4,10,0.6,3.19,0.6,15.2,15.2,0.0768,0,0,0.3,1
ENSMUSG00000030978,RRM1,ribonucleotide reductase M1,nuclear envelope|cytoplasm|cell projection|neuronal cell body|extracellular vesicular exosome|,DNA replication|metabolic process|deoxyribonucleotide biosynthetic process|protein oligomerization|protein heterotetramerization|oxidation-reduction process|,"nucleotide binding|catalytic activity|ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor|ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor|protein binding|ATP binding|oxidoreductase activity|purine nucleotide binding|",6,-0.9,7.9,3,-1.3,8.4,-1.1,15.1,-15.1,0.0771,0,0,-1.9,-0.7
ENSMUSG00000032013,TRIM29,tripartite motif-containing 29,intracellular|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of protein localization to nucleus|,p53 binding|protein binding|zinc ion binding|metal ion binding|,10,1.2,4.93,10,1.4,10.6,1.3,14.9,14.9,0.0776,0,0,0.7,2.5
ENSMUSG00000089704,GALNT2,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2,extracellular region|Golgi apparatus|Golgi apparatus|Golgi stack|Golgi lumen|membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,immunoglobulin biosynthetic process|protein O-linked glycosylation|protein O-linked glycosylation|protein O-linked glycosylation via serine|protein O-linked glycosylation via threonine|,"polypeptide N-acetylgalactosaminyltransferase activity|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|manganese ion binding|metal ion binding|",2,1.2,5.4,2,1,9.95,1,14.8,14.8,0.0779,0,0,0.7,2
ENSMUSG00000002458,RGS19,regulator of G-protein signaling 19,cytoplasm|cytoplasm|plasma membrane|brush border|membrane|clathrin-coated vesicle|,negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,G-protein alpha-subunit binding|GTPase activator activity|protein binding|,10,-0.6,7.77,10,-0.5,7.51,-0.5,14.8,-14.8,0.0779,0,0,-0.9,-0.3
ENSMUSG00000040018,COX15,cytochrome c oxidase assembly protein 15,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,heme a biosynthetic process|respiratory chain complex IV assembly|oxidation-reduction process|hydrogen ion transmembrane transport|,"catalytic activity|cytochrome-c oxidase activity|oxidoreductase activity, acting on the CH-CH group of donors|",10,0.7,8.72,10,1.3,8.18,0.7,14.8,14.8,0.0779,0,0,0.3,1.7
ENSMUSG00000023345,POC1A,POC1 centriolar protein homolog A (Chlamydomonas),spindle pole|cytoplasm|centrosome|centriole|cytoskeleton|ciliary basal body|cell projection|,biological_process|cell projection organization|,molecular_function|,9,1.6,14,9,0.5,6.46,1.5,14.8,14.8,0.0779,0,0,0.3,2.6
ENSMUSG00000022139,MBNL2,muscleblind-like 2,nucleus|cytoplasm|,"regulation of alternative mRNA splicing, via spliceosome|regulation of alternative mRNA splicing, via spliceosome|mRNA processing|RNA splicing|regulation of RNA splicing|",RNA binding|poly(A) RNA binding|metal ion binding|,10,0.9,2.02,10,1.2,13.1,1.1,14.3,14.3,0.0795,0,0,0.8,1.9
ENSMUSG00000074030,EXOC8,exocyst complex component 8,exocyst|cytoplasm|membrane|cell projection|,transport|exocytosis|protein transport|cellular protein localization|,Ral GTPase binding|phosphatidylinositol binding|,10,1.1,11.5,10,0.7,4.11,1,14.2,14.2,0.0799,0,0,0.5,1.7
ENSMUSG00000026924,SEC16A,SEC16 homolog A (S. cerevisiae),cytoplasm|Golgi apparatus|cytosol|plasma membrane|,endoplasmic reticulum organization|dephosphorylation|,inositol-polyphosphate 5-phosphatase activity|,10,0.2,2.05,9,1.4,12.6,1.3,14.1,14.1,0.0802,0,0,0.2,2.3
ENSMUSG00000019726,LYST,lysosomal trafficking regulator,cell|cytoplasm|cytosol|microtubule cytoskeleton|,neutrophil mediated immunity|T cell mediated immunity|phospholipid metabolic process|transport|microtubule-based process|lysosome organization|blood coagulation|protein transport|leukocyte chemotaxis|melanosome organization|endosome to lysosome transport via multivesicular body sorting pathway|positive regulation of natural killer cell activation|secretion of lysosomal enzymes|mast cell secretory granule organization|natural killer cell mediated cytotoxicity|response to drug|defense response to bacterium|defense response to protozoan|pigmentation|pigmentation|pigment granule organization|defense response to virus|phospholipid homeostasis|,None,10,-0.9,10,10,-0.5,4.51,-0.8,13.9,-13.9,0.081,0,0,-1.4,-0.4
ENSMUSG00000006731,B4GALNT1,"beta-1,4-N-acetyl-galactosaminyl transferase 1",Golgi apparatus|plasma membrane|membrane|integral component of membrane|integral component of Golgi membrane|,ganglioside biosynthetic process|ganglioside biosynthetic process|glycosphingolipid metabolic process|spermatogenesis|lipid storage|lipid glycosylation|,"(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity|acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,-0.4,9.37,10,-0.3,4.85,-0.4,13.8,-13.8,0.0814,0,0,-0.7,-0.2
ENSMUSG00000028651,PPIE,peptidylprolyl isomerase E (cyclophilin E),nucleus|spliceosomal complex|catalytic step 2 spliceosome|,"protein peptidyl-prolyl isomerization|regulation of transcription, DNA-templated|mRNA processing|protein folding|RNA splicing|positive regulation of viral genome replication|",nucleotide binding|nucleic acid binding|RNA binding|peptidyl-prolyl cis-trans isomerase activity|isomerase activity|poly(A) RNA binding|,10,0.8,12.7,8,-1.1,5.83,0.7,13.7,13.7,0.0818,0,0,0.3,1.7
ENSMUSG00000032518,RPSA,ribosomal protein SA,basement membrane|intracellular|nucleus|cytoplasm|cytoplasm|cytosol|ribosome|plasma membrane|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|90S preribosome|extracellular matrix|neuronal cell body|extracellular vesicular exosome|,"ribosomal small subunit assembly|endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|rRNA export from nucleus|translation|single organismal cell-cell adhesion|",structural constituent of ribosome|laminin receptor activity|ribosome binding|laminin binding|poly(A) RNA binding|,3,-1.1,13.7,0,0,0,-1.1,13.5,-13.5,0.0824,0,0,-2,-0.7
ENSMUSG00000030298,SEC13,SEC13 homolog (S. cerevisiae),kinetochore|intracellular|cell|nucleus|nuclear envelope|nuclear pore|endoplasmic reticulum|membrane|nuclear pore outer ring|cytoplasmic vesicle|extracellular vesicular exosome|,transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|mRNA transport|,None,9,-1.1,5.37,9,1,13,0.8,13.5,13.5,0.0824,0,0,0.4,1.6
ENSMUSG00000054226,TPRKB,Tp53rk binding protein,nucleus|cytoplasm|cytosol|,tRNA processing|biological_process|,protein kinase binding|protein kinase binding|,9,0.7,6.61,9,0.8,7.37,0.8,13.5,13.5,0.0824,0,0,0.4,1.4
ENSMUSG00000013846,ST3GAL1,"ST3 beta-galactoside alpha-2,3-sialyltransferase 1",extracellular region|Golgi apparatus|membrane|membrane|integral component of membrane|integral component of Golgi membrane|extracellular vesicular exosome|,protein phosphorylation|protein glycosylation|protein glycosylation|sialylation|,"beta-galactoside (CMP) alpha-2,3-sialyltransferase activity|beta-galactoside (CMP) alpha-2,3-sialyltransferase activity|sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.5,6.89,10,0.6,7.15,0.5,13.4,13.4,0.0829,0,0,0.3,1
ENSMUSG00000010517,FAF1,Fas-associated factor 1,nucleus|nuclear envelope|cytoplasm|cytosol|Cdc48p-Npl4p-Ufd1p AAA ATPase complex|perinuclear region of cytoplasm|,apoptotic process|cytoplasmic sequestering of NF-kappaB|cell death|regulation of cell adhesion|positive regulation of protein complex assembly|regulation of protein catabolic process|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|,protein binding|protein kinase binding|protein domain specific binding|heat shock protein binding|ubiquitin protein ligase binding|ubiquitin binding|NF-kappaB binding|,10,0.2,0.588,10,1,13.1,1,13.3,13.3,0.0833,0,0,0.6,1.7
ENSMUSG00000034602,MON2,MON2 homolog (yeast),trans-Golgi network|,transport|protein transport|vesicle-mediated transport|actin cytoskeleton organization|positive regulation of GTPase activity|,ARF guanyl-nucleotide exchange factor activity|,10,0.8,13.8,10,0.3,0.871,0.7,13.3,13.3,0.0833,0,0,0.3,1.3
ENSMUSG00000070632,BTBD8,BTB (POZ) domain containing 8,nucleus|,biological_process|,molecular_function|,10,0.3,0.802,10,0.9,13.3,0.9,13.2,13.2,0.0837,0,0,0.5,1.7
ENSMUSG00000074811,HPS6,Hermansky-Pudlak syndrome 6,cytoplasm|endosome|endoplasmic reticulum|membrane|membrane|BLOC-2 complex|intracellular membrane-bounded organelle|,organelle organization|blood coagulation|melanocyte differentiation|pigmentation|protein localization to membrane|,protein binding|Rab GTPase binding|GTP-dependent protein binding|,9,0.7,10.7,9,0.3,4.87,0.5,13,13,0.0847,0,0,0.2,1.1
ENSMUSG00000019303,PSMC3IP,"proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein",proteasome complex|nucleus|,DNA recombination|meiotic nuclear division|positive regulation of transcription from RNA polymerase II promoter|regulation of RNA biosynthetic process|,DNA binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|glucocorticoid receptor binding|protein homodimerization activity|thyroid hormone receptor binding|androgen receptor binding|DBD domain binding|,10,0.5,8.17,10,0.7,5.79,0.5,13,13,0.0847,0,0,0.2,1
ENSMUSG00000022111,UCHL3,ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase),intracellular|nucleus|cytoplasm|extracellular vesicular exosome|,proteolysis|ubiquitin-dependent protein catabolic process|adult walking behavior|protein deubiquitination|protein catabolic process|protein catabolic process|cellular response to insulin stimulus|eating behavior|positive regulation of fat cell differentiation|retina development in camera-type eye|,ubiquitin-specific protease activity|peptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitin binding|,10,-0.5,12.7,10,-0.9,1.19,-0.5,13,-13,0.0847,0,0,-1.1,-0.2
ENSMUSG00000034667,XPOT,"exportin, tRNA (nuclear export receptor for tRNAs)",nucleus|nuclear pore|nucleoplasm|cytoplasm|,tRNA export from nucleus|transport|intracellular protein transport|,tRNA binding|RNA binding|Ran GTPase binding|,10,0.7,6.54,10,0.5,7.08,0.6,12.9,12.9,0.0853,0,0,0.3,1.1
ENSMUSG00000034160,OGT,O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase),histone acetyltransferase complex|intracellular|nucleus|nucleus|cytoplasm|cytoplasm|microtubule organizing center|cytosol|plasma membrane|membrane|MLL5-L complex|,regulation of glycolytic process|protein O-linked glycosylation|protein O-linked glycosylation|protein O-linked glycosylation|protein O-linked glycosylation|apoptotic process|chromatin modification|positive regulation of granulocyte differentiation|negative regulation of protein ubiquitination|response to insulin|circadian regulation of gene expression|regulation of Rac protein signal transduction|positive regulation of catalytic activity|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|positive regulation of proteolysis|positive regulation of transcription from RNA polymerase II promoter|regulation of insulin receptor signaling pathway|phosphatidylinositol-mediated signaling|rhythmic process|positive regulation of histone H3-K4 methylation|positive regulation of histone H3-K27 methylation|protein homotrimerization|cellular response to retinoic acid|histone H3-K4 trimethylation|regulation of gluconeogenesis involved in cellular glucose homeostasis|,"catalytic activity|protein binding|phosphatidylinositol-3,4,5-trisphosphate binding|enzyme activator activity|N-acetyltransferase activity|lipid binding|protein N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|peptide binding|histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|histone acetyltransferase activity (H4-K16 specific)|monosaccharide binding|protein O-GlcNAc transferase activity|",8,0.5,5.63,8,0.8,7.8,0.7,12.5,12.5,0.0874,0,0,0.3,1.4
ENSMUSG00000025436,XRCC6BP1,XRCC6 binding protein 1,cellular_component|,proteolysis|biological_process|,molecular_function|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.5,7.75,10,0.4,5.22,0.4,12.5,12.5,0.0874,0,0,0.2,0.8
ENSMUSG00000020220,VPS13D,vacuolar protein sorting 13 D (yeast),extracellular vesicular exosome|,biological_process|,molecular_function|,9,1.3,12,9,-1,5.01,1.2,12.4,12.4,0.088,0,0,0.8,2
ENSMUSG00000029145,EIF2B4,"eukaryotic translation initiation factor 2B, subunit 4 delta",cytoplasm|cytoplasm|eukaryotic translation initiation factor 2B complex|eukaryotic translation initiation factor 2B complex|,ovarian follicle development|translation|translational initiation|regulation of translation|regulation of translational initiation|response to heat|response to glucose|oligodendrocyte development|negative regulation of translational initiation in response to stress|myelination|response to peptide hormone|positive regulation of GTPase activity|positive regulation of GTPase activity|cellular metabolic process|negative regulation of translational initiation|cellular response to stimulus|,translation initiation factor activity|guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|translation initiation factor binding|,8,-0.2,0.398,9,-1,14.1,-0.9,12.4,-12.4,0.088,0,0,-1.8,-0.5
ENSMUSG00000020196,CABIN1,calcineurin binding protein 1,nucleus|cytoplasm|aggresome|,DNA replication-independent nucleosome assembly|signal transduction|negative regulation of catalytic activity|negative regulation of cell death|,protein phosphatase inhibitor activity|protein domain specific binding|protein phosphatase 2B binding|,10,-0.6,10.7,10,-0.3,2.74,-0.4,12.4,-12.4,0.088,0,0,-1,-0.2
ENSMUSG00000029763,EXOC4,exocyst complex component 4,exocyst|cytoplasm|endosome|Golgi apparatus|postsynaptic density|membrane|growth cone|growth cone membrane|myelin sheath abaxonal region|neuron projection|neuronal cell body|dendritic shaft|myelin sheath|protein complex|synapse|,protein targeting to membrane|transport|exocytosis|vesicle docking involved in exocytosis|synaptic transmission|protein transport|establishment of cell polarity|membrane biogenesis|oligodendrocyte differentiation|positive regulation of calcium-mediated signaling|regulation of protein transport|Golgi to transport vesicle transport|,protein binding|PDZ domain binding|PDZ domain binding|protein complex binding|protein N-terminus binding|,10,1.1,2.97,10,1,9.94,1,12.4,12.4,0.088,0,0,0.5,1.8
ENSMUSG00000036473,TBC1D24,"TBC1 domain family, member 24",cytoplasm|,neuron projection development|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,0.4,4.74,10,0.5,8.12,0.4,12.2,12.2,0.0893,0,0,0.2,0.9
ENSMUSG00000031352,HCCS,holocytochrome c synthetase,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,None,holocytochrome-c synthase activity|protein binding|lyase activity|metal ion binding|,10,0.8,4.21,10,0.9,8.52,0.8,12.2,12.2,0.0893,0,0,0.4,1.5
ENSMUSG00000022300,DCAF13,DDB1 and CUL4 associated factor 13,nucleus|ribonucleoprotein complex|Cul4-RING E3 ubiquitin ligase complex|,rRNA processing|biological_process|ribosome biogenesis|,poly(A) RNA binding|,9,1.1,11.1,8,0.6,2.59,1,12.1,12.1,0.0899,0,0,0.4,1.7
ENSMUSG00000020792,EXOC7,exocyst complex component 7,exocyst|cytoplasm|microtubule organizing center|plasma membrane|membrane|membrane|growth cone membrane|centriolar satellite|,transport|exocytosis|biological_process|protein transport|,protein binding|,10,0.4,5.09,10,0.4,7.35,0.4,12.1,12.1,0.0899,0,0,0.2,0.8
ENSMUSG00000031986,SPRTN,SprT-like N-terminal domain,nucleus|chromosome|nuclear speck|,DNA repair|cellular response to DNA damage stimulus|response to UV|translesion synthesis|positive regulation of protein ubiquitination|,ubiquitin binding|metal ion binding|K63-linked polyubiquitin binding|,9,-1.3,15.1,8,0.5,4.21,-1.2,12.1,-12.1,0.0899,0,0,-2,-0.3
ENSMUSG00000039753,FBXL5,F-box and leucine-rich repeat protein 5,cytoplasm|SCF ubiquitin ligase complex|perinuclear region of cytoplasm|,protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|iron ion homeostasis|,iron ion binding|metal ion binding|,10,0.5,2.37,10,0.9,10.1,0.8,12,12,0.0906,0,0,0.4,1.6
ENSMUSG00000021752,KCTD6,potassium channel tetramerisation domain containing 6,cellular_component|,transport|ion transport|protein homooligomerization|,ankyrin binding|,10,-1.2,14.8,10,0.2,1.16,-1.2,11.7,-11.7,0.0925,0,0,-2,-0.3
ENSMUSG00000026819,SLC25A25,"solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,response to dietary excess|transport|response to activity|response to food|multicellular organism growth|camera-type eye development|cellular respiration|ATP metabolic process|transmembrane transport|adipose tissue development|calcium ion transmembrane transport|,calcium ion binding|metal ion binding|,9,0.4,5.77,9,0.6,6.58,0.5,11.6,11.6,0.0932,0,0,0.2,0.9
ENSMUSG00000078671,CHD2,chromodomain helicase DNA binding protein 2,nucleus|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|muscle organ development|chromatin modification|hematopoietic stem cell differentiation|",nucleotide binding|core promoter sequence-specific DNA binding|DNA binding|helicase activity|protein binding|ATP binding|hydrolase activity|histone binding|poly(A) RNA binding|,10,-0.5,8.17,10,-0.5,3.83,-0.5,11.6,-11.6,0.0932,0,0,-0.9,-0.2
ENSMUSG00000002741,YKT6,YKT6 homolog (S. Cerevisiae),cytoplasm|mitochondrion|endosome|endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|SNARE complex|cytoplasmic vesicle|extracellular vesicular exosome|,"transport|ER to Golgi vesicle-mediated transport|ER to Golgi vesicle-mediated transport|vesicle targeting|vesicle targeting|vesicle docking involved in exocytosis|vesicle docking involved in exocytosis|metabolic process|protein transport|vesicle-mediated transport|retrograde transport, endosome to Golgi|","dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|SNAP receptor activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-palmitoyltransferase activity|protein-cysteine S-palmitoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",9,0.7,7.54,9,0.7,4.31,0.7,11.5,11.5,0.094,0,0,0.4,1.5
ENSMUSG00000018583,G3BP1,GTPase activating protein (SH3 domain) binding protein 1,intracellular|nucleus|cytoplasm|plasma membrane|cytoplasmic stress granule|membrane|,transport|negative regulation of canonical Wnt signaling pathway|,nucleotide binding|nucleic acid binding|DNA binding|RNA binding|mRNA binding|helicase activity|nuclease activity|endonuclease activity|protein binding|ATP binding|hydrolase activity|poly(A) RNA binding|,10,0.5,4.6,10,0.8,7.68,0.6,11.4,11.4,0.0948,0,0,0.3,1.3
ENSMUSG00000069265,HIST1H3A,"histone cluster 1, H3a",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,None,4,-0.4,2.93,4,-0.9,10.1,-0.8,11.4,-11.4,0.0948,0,0,-1.9,-0.4
ENSMUSG00000024143,RHOQ,"ras homolog gene family, member Q",intracellular|cytoplasm|actin filament|plasma membrane|membrane|membrane raft|,GTP catabolic process|GTP catabolic process|small GTPase mediated signal transduction|insulin receptor signaling pathway|regulation of cell shape|actin cytoskeleton organization|cortical actin cytoskeleton organization|cortical actin cytoskeleton organization|cellular response to insulin stimulus|cellular response to insulin stimulus|positive regulation of transcription from RNA polymerase II promoter|negative regulation of glucose import|positive regulation of glucose import|positive regulation of filopodium assembly|negative regulation of establishment of protein localization to plasma membrane|negative regulation of establishment of protein localization to plasma membrane|,nucleotide binding|GTPase activity|GTPase activity|protein binding|profilin binding|GTP binding|GBD domain binding|,10,0.1,0.168,10,0.6,12.6,0.6,11.3,11.3,0.0955,0,0,0.3,1.3
ENSMUSG00000094338,HIST1H2BL,"histone cluster 1, H2bl",extracellular space|nucleus|extracellular vesicular exosome|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,molecular_function|,7,-1.2,13.7,6,0.5,4.6,-1.2,11.3,-11.3,0.0955,0,0,-2,2.1
ENSMUSG00000024847,AIP,aryl-hydrocarbon receptor-interacting protein,nucleus|cytoplasm|cytosol|plasma membrane|membrane|,protein folding|protein targeting to mitochondrion|xenobiotic metabolic process|regulation of protein kinase A signaling|protein maturation by protein folding|negative regulation of cyclic-nucleotide phosphodiesterase activity|regulation of RNA biosynthetic process|,transcription cofactor activity|protein binding|GAF domain binding|unfolded protein binding|,9,0.8,8.91,8,1.2,3.65,0.9,11.3,11.3,0.0955,0,0,0.4,1.7
ENSMUSG00000040550,OTUD6B,OTU domain containing 6B,cellular_component|,proteolysis|biological_process|,molecular_function|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.5,6.3,10,0.4,5.23,0.4,11.2,11.2,0.0964,0,0,0.2,0.8
ENSMUSG00000047648,FBXO30,F-box protein 30,cellular_component|,biological_process|protein ubiquitination|,ubiquitin-protein transferase activity|zinc ion binding|metal ion binding|,10,0.4,2.17,10,-0.6,13.1,-0.6,11.1,-11.1,0.0972,0,0,-1.3,-0.2
ENSMUSG00000061477,RPS7,ribosomal protein S7,intracellular|nucleus|nucleolus|cytoplasm|ribosome|cytoskeleton|membrane|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|90S preribosome|small-subunit processome|extracellular vesicular exosome|,neural tube closure|cytoplasmic translation|rRNA processing|rRNA processing|translation|cell differentiation|ribosomal small subunit biogenesis|ribosomal small subunit biogenesis|,structural constituent of ribosome|poly(A) RNA binding|,4,-0.9,5.58,4,-0.7,6.14,-0.8,11.1,-11.1,0.0972,0,0,-2,-0.3
ENSMUSG00000036693,NOP14,NOP14 nucleolar protein,nucleus|nucleolus|membrane|small-subunit processome|,rRNA processing|biological_process|ribosome biogenesis|,enzyme binding|poly(A) RNA binding|,9,0.5,4.3,9,0.9,8.21,0.8,11.1,11.1,0.0972,0,0,0.4,1.6
ENSMUSG00000021193,PITRM1,pitrilysin metallepetidase 1,mitochondrion|mitochondrion|mitochondrial matrix|,proteolysis|,catalytic activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.6,4.69,9,0.9,7.06,0.8,11.1,11.1,0.0972,0,0,0.3,1.5
ENSMUSG00000075701,VIMP,VCP-interacting membrane protein,cytoplasm|endoplasmic reticulum|cytoplasmic microtubule|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|very-low-density lipoprotein particle|low-density lipoprotein particle|,"negative regulation of acute inflammatory response to antigenic stimulus|intracellular protein transport|ER overload response|ER-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum unfolded protein response|retrograde protein transport, ER to cytosol|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|cellular response to oxidative stress|cell redox homeostasis|negative regulation of inflammatory response|negative regulation of nitric-oxide synthase biosynthetic process|response to redox state|cellular response to lipopolysaccharide|regulation of nitric oxide metabolic process|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of macrophage apoptotic process|",protein binding|selenium binding|antioxidant activity|enzyme binding|,10,-0.6,10.1,10,-0.3,1.92,-0.5,11,-11,0.0981,0,0,-1.1,-0.2
ENSMUSG00000041278,TTC1,tetratricopeptide repeat domain 1,peroxisomal membrane|,biological_process|,molecular_function|,9,-1.1,9.83,8,0.8,4.3,-1,11,-11,0.0981,0,0,-2,0.9
ENSMUSG00000019088,DNASE1L1,deoxyribonuclease 1-like 1,endoplasmic reticulum|extracellular vesicular exosome|,DNA catabolic process|,"nuclease activity|endonuclease activity|deoxyribonuclease activity|hydrolase activity|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|",10,0.5,5.91,10,0.6,5.44,0.6,10.9,10.9,0.0989,0,0,0.2,1.1
ENSMUSG00000048578,MLEC,malectin,endoplasmic reticulum|membrane|membrane|integral component of membrane|,carbohydrate metabolic process|,enzyme binding|,10,-0.6,9.12,10,-0.3,2.68,-0.5,10.7,-10.7,0.101,0,0,-1.1,-0.2
ENSMUSG00000024785,RCL1,RNA terminal phosphate cyclase-like 1,nucleus|nucleolus|,rRNA processing|RNA processing|ribosome biogenesis|,catalytic activity|,8,1.4,7.79,8,0.7,5.35,1.3,10.7,10.7,0.101,0,0,0.5,2.5
ENSMUSG00000024074,CRIM1,cysteine rich transmembrane BMP regulator 1 (chordin like),extracellular region|membrane|integral component of membrane|extracellular vesicular exosome|,regulation of cell growth|,enzyme inhibitor activity|serine-type endopeptidase inhibitor activity|insulin-like growth factor binding|PDZ domain binding|,10,-0.1,0.0972,10,1,12.1,0.9,10.6,10.6,0.102,0,0,0.4,1.7
ENSMUSG00000008482,RNF151,ring finger protein 151,nucleus|cytoplasm|,spermatogenesis|protein ubiquitination|cell differentiation|,ubiquitin-protein transferase activity|zinc ion binding|metal ion binding|,10,0.8,0.916,10,0.6,9.74,0.6,10.2,10.2,0.105,0,0,0.3,1.4
ENSMUSG00000038095,SBNO1,"sno, strawberry notch homolog 1 (Drosophila)",cellular_component|,"regulation of transcription, DNA-templated|biological_process|",molecular_function|,9,-0.7,1.24,9,-0.7,9.06,-0.7,10,-10,0.107,0,0,-1.5,-0.2
ENSMUSG00000040613,APOBEC1,"apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1",nucleus|cytoplasm|,mRNA processing|response to osmotic stress|cytidine deamination|response to gamma radiation|cytidine to uridine editing|cytidine to uridine editing|mRNA modification|mRNA modification|regulation of cell proliferation|lipoprotein metabolic process|lipoprotein biosynthetic process|response to drug|lipoprotein transport|response to ethanol|mRNA stabilization|response to calcium ion|defense response to virus|DNA demethylation|negative regulation of methylation-dependent chromatin silencing|,"catalytic activity|GTP cyclohydrolase activity|cytidine deaminase activity|tRNA-specific adenosine deaminase activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines|AU-rich element binding|N-cyclopropylmelamine deaminase activity|N-cyclopropylammeline deaminase activity|N-cyclopropylammelide alkylamino hydrolase activity|2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity|tRNA-specific adenosine-37 deaminase activity|archaeal-specific GTP cyclohydrolase activity|metal ion binding|tRNA-specific adenosine-34 deaminase activity|",10,0.4,2.26,10,0.6,8.48,0.5,10,10,0.107,0,0,0.2,1.2
ENSMUSG00000031143,CCDC22,coiled-coil domain containing 22,cellular_component|,biological_process|,protein binding|,10,0.8,5.69,9,0.7,4.72,0.7,9.92,9.92,0.108,0,0,0.4,1.5
ENSMUSG00000029816,GPNMB,glycoprotein (transmembrane) nmb,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|,cell adhesion|,integrin binding|heparin binding|,10,-0.5,8.1,10,-0.6,2.22,-0.6,9.89,-9.89,0.109,0,0,-1.2,-0.2
ENSMUSG00000038633,DEGS1,degenerative spermatocyte homolog 1 (Drosophila),mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|sphingolipid biosynthetic process|oxidation-reduction process|,"oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|fluorene oxygenase activity|mono-butyltin dioxygenase activity|tri-n-butyltin dioxygenase activity|di-n-butyltin dioxygenase activity|methylsilanetriol hydroxylase activity|methyl tertiary butyl ether 3-monooxygenase activity|4-nitrocatechol 4-monooxygenase activity|4-chlorophenoxyacetate monooxygenase activity|tert-butanol 2-monooxygenase activity|alpha-pinene monooxygenase activity|dimethylsilanediol hydroxylase activity|ammonia monooxygenase activity|hydroxymethylsilanetriol oxidase activity|2-hydroxyisobutyrate 3-monooxygenase activity|alpha-pinene dehydrogenase activity|bisphenol A hydroxylase B activity|2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity|9-fluorenone-3,4-dioxygenase activity|anthracene 9,10-dioxygenase activity|2-(methylthio)benzothiazole monooxygenase activity|2-hydroxybenzothiazole monooxygenase activity|benzothiazole monooxygenase activity|2,6-dihydroxybenzothiazole monooxygenase activity|pinacolone 5-monooxygenase activity|thioacetamide S-oxygenase activity|thioacetamide S-oxide S-oxygenase activity|endosulfan monooxygenase I activity|N-nitrodimethylamine hydroxylase activity|4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity|endosulfan ether monooxygenase activity|pyrene 4,5-monooxygenase activity|pyrene 1,2-monooxygenase activity|1-hydroxypyrene 6,7-monooxygenase activity|1-hydroxypyrene 7,8-monooxygenase activity|phenylboronic acid monooxygenase activity|spheroidene monooxygenase activity|",10,0.5,5.4,10,0.8,5.7,0.6,9.89,9.89,0.109,0,0,0.2,1.3
ENSMUSG00000008373,PRPF31,PRP31 pre-mRNA processing factor 31 homolog (yeast),nucleus|spliceosomal complex|U4 snRNP|Cajal body|nuclear speck|ribonucleoprotein complex|U4/U6 x U5 tri-snRNP complex|MLL1 complex|,"spliceosomal tri-snRNP complex assembly|spliceosomal tri-snRNP complex assembly|mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",RNA binding|ribonucleoprotein complex binding|poly(A) RNA binding|snRNP binding|,10,0.3,2.36,10,1.3,11.6,1.2,9.89,9.89,0.109,0,0,0.5,2
ENSMUSG00000028514,USP24,ubiquitin specific peptidase 24,cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,-0.3,4.23,10,-0.5,6.88,-0.4,9.89,-9.89,0.109,0,0,-0.9,-0.1
ENSMUSG00000045409,TRIM39,tripartite motif-containing 39,intracellular|cytoplasm|mitochondrion|cytosol|,apoptotic process|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of apoptotic signaling pathway|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|identical protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.5,2.59,10,0.4,7.6,0.4,9.85,9.85,0.109,0,0,0.2,1
ENSMUSG00000021282,EIF5,eukaryotic translation initiation factor 5,cytoplasm|plasma membrane|,translation|translational initiation|,nucleotide binding|translation initiation factor activity|GTP binding|poly(A) RNA binding|,7,-1,11.9,5,1,5.06,-1,9.79,-9.79,0.11,0,0,-2,1.6
ENSMUSG00000020412,ASCC2,activating signal cointegrator 1 complex subunit 2,cellular_component|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,10,0.4,2.22,10,0.5,7.86,0.4,9.59,9.59,0.112,0,0,0.1,1
ENSMUSG00000033128,GGA1,"golgi associated, gamma adaptin ear containing, ARF binding protein 1",intracellular|nucleus|endosome|Golgi apparatus|membrane|membrane|clathrin adaptor complex|intracellular membrane-bounded organelle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|positive regulation of protein catabolic process|,protein binding|,10,0.4,6.94,10,0.7,3.84,0.6,9.52,9.52,0.113,0,0,0.2,2
ENSMUSG00000001865,CPA3,"carboxypeptidase A3, mast cell",cytoplasmic vesicle|,regulation of angiotensin levels in blood|proteolysis|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.6,9.93,-0.6,9.51,-9.51,0.113,0,0,-1.2,-0.2
ENSMUSG00000020649,RRM2,ribonucleotide reductase M2,nucleus|nuclear envelope|cytoplasm|,DNA replication|deoxyribonucleoside diphosphate metabolic process|deoxyribonucleotide metabolic process|deoxyribonucleotide biosynthetic process|protein oligomerization|protein heterotetramerization|oxidation-reduction process|,"ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor|ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor|ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor|protein binding|oxidoreductase activity|metal ion binding|",6,1,1,6,-1,11,-1,9.5,-9.5,0.113,0,0,-1.9,-0.4
ENSMUSG00000030058,COPG1,"coatomer protein complex, subunit gamma 1",Golgi membrane|cytoplasm|Golgi apparatus|membrane|membrane coat|COPI vesicle coat|cytoplasmic vesicle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|establishment of Golgi localization|organelle transport along microtubule|,structural molecule activity|,10,0.8,7.79,9,-0.8,4.84,0.6,9.46,9.46,0.113,0,0,-0.1,2
ENSMUSG00000040181,FMO1,flavin containing monooxygenase 1,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,organic acid metabolic process|toxin metabolic process|drug metabolic process|oxidation-reduction process|NADPH oxidation|,"monooxygenase activity|monooxygenase activity|N,N-dimethylaniline monooxygenase activity|oxidoreductase activity|flavin adenine dinucleotide binding|NADP binding|",10,-0.2,0.583,10,-1.4,12.4,-1.4,9.41,-9.41,0.114,0,0,-2.8,-0.2
ENSMUSG00000030779,RBBP6,retinoblastoma binding protein 6,nucleus|chromosome|cytoplasm|cytoskeleton|,in utero embryonic development|multicellular organism growth|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|embryonic organ development|somite development|,"nucleic acid binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.9,7.01,8,1,3.17,-1,9.38,-9.38,0.115,0,0,-2,1.2
ENSMUSG00000053774,UBXN7,UBX domain protein 7,nucleus|Cdc48p-Npl4p-Ufd1p AAA ATPase complex|,biological_process|,transcription factor binding|ubiquitin protein ligase binding|ubiquitin binding|,10,-0.6,6.06,10,-0.5,3.61,-0.6,9.27,-9.27,0.116,0,0,-1.4,-0.2
ENSMUSG00000014077,CHP1,calcineurin-like EF hand protein 1,Golgi membrane|nucleus|cytoplasm|endoplasmic reticulum|cytosol|cytoskeleton|plasma membrane|microtubule cytoskeleton|membrane|transport vesicle|extracellular vesicular exosome|,microtubule bundle formation|negative regulation of protein phosphorylation|negative regulation of protein kinase activity|protein export from nucleus|transport|negative regulation of phosphatase activity|protein transport|calcium ion-dependent exocytosis|membrane docking|cytoplasmic microtubule organization|negative regulation of protein ubiquitination|negative regulation of protein autophosphorylation|negative regulation of NF-kappaB transcription factor activity|positive regulation of sodium:proton antiporter activity|negative regulation of protein import into nucleus|transcytosis|protein stabilization|positive regulation of protein transport|protein oligomerization|regulation of intracellular pH|positive regulation of protein glycosylation|membrane organization|membrane fusion|negative regulation of calcineurin-NFAT signaling cascade|,protein kinase inhibitor activity|transporter activity|calcium ion binding|microtubule binding|kinase binding|metal ion binding|calcium-dependent protein binding|,10,-0.6,11.3,10,-1.7,0.944,-0.6,9.26,-9.26,0.116,0,0,-2,-0.3
ENSMUSG00000002820,ATG4D,"autophagy related 4D, cysteine peptidase",cytoplasm|mitochondrion|,proteolysis|transport|autophagy|apoptotic process|protein transport|,cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.4,4.11,10,0.4,5.47,0.4,9.22,9.22,0.117,0,0,0.2,0.9
ENSMUSG00000031657,HEATR3,HEAT repeat containing 3,cellular_component|,biological_process|,molecular_function|,10,1.8,7.14,10,0.4,5.46,0.5,9.1,9.1,0.119,0,0,0.1,2.5
ENSMUSG00000003235,EIF2B5,"eukaryotic translation initiation factor 2B, subunit 5 epsilon",nucleus|cytoplasm|cytoplasm|eukaryotic translation initiation factor 2B complex|,ovarian follicle development|translation|translational initiation|regulation of translation|response to heat|response to glucose|astrocyte development|oligodendrocyte development|negative regulation of translational initiation in response to stress|response to endoplasmic reticulum stress|cellular response to drug|myelination|response to peptide hormone|positive regulation of GTPase activity|astrocyte differentiation|,translation initiation factor activity|guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|translation initiation factor binding|,7,-0.2,1.06,8,1.2,10.5,1.1,9.1,9.1,0.119,0,0,0.5,2
ENSMUSG00000079658,TCEB1,"transcription elongation factor B (SIII), polypeptide 1",nucleus|VCB complex|elongin complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|ubiquitin-dependent protein catabolic process|",protein binding|protein complex binding|,10,1.1,4.98,10,0.4,4.71,0.4,9.07,9.07,0.119,0,0,0.1,1.4
ENSMUSG00000018669,CDK5RAP3,CDK5 regulatory subunit associated protein 3,membrane|,regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of transcription from RNA polymerase II promoter|protein ufmylation|,protein binding|protein complex binding|,10,0.4,3.48,10,0.5,5.96,0.5,9.04,9.04,0.119,0,0,0.1,1
ENSMUSG00000043510,HSCB,HscB iron-sulfur cluster co-chaperone homolog (E. coli),cytoplasm|mitochondrion|mitochondrion|centrosome|plasma membrane|,protein folding|iron-sulfur cluster assembly|protein oligomerization|,molecular_function|metal ion binding|chaperone binding|,10,1.1,3.82,10,0.8,6.06,0.9,8.99,8.99,0.12,0,0,0.4,1.8
ENSMUSG00000022338,ENY2,enhancer of yellow 2 homolog (Drosophila),SAGA complex|nucleus|nuclear pore|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA export from nucleus|transport|protein transport|chromatin modification|histone deubiquitination|positive regulation of transcription, DNA-templated|mRNA transport|",transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity|,6,0.6,4.31,6,0.7,5.25,0.6,8.98,8.98,0.12,0,0,0.2,1.5
ENSMUSG00000026111,UNC50,unc-50 homolog (C. elegans),Golgi membrane|nucleus|nuclear inner membrane|Golgi apparatus|membrane|integral component of membrane|,transport|cell surface receptor signaling pathway|protein transport|,RNA binding|,10,1.2,8.61,10,0.4,3.83,1,8.95,8.95,0.121,0,0,0.3,1.8
ENSMUSG00000022437,SAMM50,sorting and assembly machinery component 50 homolog (S. cerevisiae),mitochondrial sorting and assembly machinery complex|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|integral component of membrane|outer membrane|extracellular vesicular exosome|,protein import into mitochondrial outer membrane|,protein binding|,9,1.3,8.01,8,0.4,2.14,0.5,8.78,8.78,0.124,0,0,0.2,2
ENSMUSG00000031600,VPS37A,vacuolar protein sorting 37A (yeast),ESCRT I complex|nucleus|cytoplasm|endosome|centrosome|membrane|intracellular membrane-bounded organelle|,transport|protein transport|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|,molecular_function|,9,1.8,6.01,10,-0.4,6.45,-0.3,8.77,-8.77,0.124,0,0,-1.4,2.2
ENSMUSG00000006299,AAMP,angio-associated migratory protein,cell surface|,biological_process|,molecular_function|,10,0.9,7.55,10,-0.7,11.6,-0.7,8.74,-8.74,0.124,0,0,-2,1.6
ENSMUSG00000042396,RBM7,RNA binding motif protein 7,nucleus|,meiotic nuclear division|biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.4,4.43,10,0.6,4.78,0.5,8.62,8.62,0.127,0,0,0.1,1
ENSMUSG00000027865,GDAP2,ganglioside-induced differentiation-associated-protein 2,lysosomal membrane|,response to retinoic acid|,molecular_function|,10,0.4,4.03,10,0.6,5.19,0.6,8.61,8.61,0.127,0,0,0.1,1.3
ENSMUSG00000034566,ATP5H,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D","mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|proton-transporting ATP synthase complex, coupling factor F(o)|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|ATP synthesis coupled proton transport|proton transport|ATP metabolic process|,hydrogen ion transmembrane transporter activity|ATPase activity|,7,0.4,1.56,7,0.8,8.21,0.7,8.61,8.61,0.127,0,0,-1.5,2
ENSMUSG00000022838,EAF2,ELL associated factor 2,nucleus|nucleoplasm|ELL-EAF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of cell growth|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of epithelial cell proliferation involved in prostate gland development|intrinsic apoptotic signaling pathway|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|protein binding|,10,-0.6,6.2,10,-1,2.99,-0.6,8.54,-8.54,0.128,0,0,-1.5,-0.2
ENSMUSG00000022498,TXNDC11,thioredoxin domain containing 11,endoplasmic reticulum|membrane|integral component of membrane|,protein folding|response to endoplasmic reticulum stress|cell redox homeostasis|,protein disulfide isomerase activity|,10,0.6,6.6,10,0.4,2.6,0.5,8.53,8.53,0.128,0,0,0.2,1.2
ENSMUSG00000040703,CYP2S1,"cytochrome P450, family 2, subfamily s, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|metal ion binding|aromatase activity|",10,-0.6,11.1,10,0,0,-0.6,8.42,-8.42,0.13,0,0,-1.4,-0.2
ENSMUSG00000033184,TMED7,transmembrane emp24 protein transport domain containing 7,endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.6,3.5,10,0.6,5.09,0.6,8.25,8.25,0.133,0,0,0.2,1.4
ENSMUSG00000069301,HIST1H2AG,"histone cluster 1, H2ag",nucleus|extracellular vesicular exosome|,biological_process|,None,0,0,0,3,-1.2,8.42,-1.2,8.23,-8.23,0.134,0,0,-2,-0.5
ENSMUSG00000006764,TPH2,tryptophan hydroxylase 2,neuron projection|,serotonin biosynthetic process from tryptophan|metabolic process|aromatic amino acid family metabolic process|serotonin biosynthetic process|oxidation-reduction process|,"monooxygenase activity|tryptophan 5-monooxygenase activity|iron ion binding|oxidoreductase activity|amino acid binding|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen|metal ion binding|",10,0.6,8.98,10,0.2,0.649,0.5,8.18,8.18,0.135,0,0,0.1,1.2
ENSMUSG00000035373,CCL7,chemokine (C-C motif) ligand 7,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|cellular response to ethanol|,cytokine activity|chemokine activity|heparin binding|CCR2 chemokine receptor binding|,10,0,0,9,0.7,10.8,0.7,8.17,8.17,0.135,0,0,0.3,1.7
ENSMUSG00000042447,MIOS,"missing oocyte, meiosis regulator, homolog (Drosophila)",lysosomal membrane|,biological_process|,molecular_function|,10,0.3,2.48,10,0.7,7.51,0.6,8.14,8.14,0.136,0,0,0.2,1.3
ENSMUSG00000032575,MANF,mesencephalic astrocyte-derived neurotrophic factor,extracellular region|nucleus|,vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure|response to unfolded protein|,growth factor activity|poly(A) RNA binding|,10,0.3,2.48,10,0.6,7.3,0.5,8.14,8.14,0.136,0,0,0.1,1.9
ENSMUSG00000031371,HAUS7,"HAUS augmin-like complex, subunit 7",nucleolus|cytoplasm|centrosome|cytoskeleton|microtubule|plasma membrane|HAUS complex|,cell cycle|mitotic nuclear division|spindle assembly|centrosome organization|cell division|,thioesterase binding|,5,-0.9,2.51,6,-1.2,6.32,-1.1,8.12,-8.12,0.136,0,0,-2,-0.6
ENSMUSG00000024856,CDK2AP2,CDK2-associated protein 2,cellular_component|,biological_process|,molecular_function|,10,0.3,1.62,10,0.5,7.31,0.5,8.08,8.08,0.137,0,0,0.1,1.1
ENSMUSG00000035237,LCAT,lecithin cholesterol acyltransferase,extracellular region|extracellular space|extracellular space|high-density lipoprotein particle|extracellular vesicular exosome|,lipid metabolic process|phospholipid metabolic process|phosphatidylcholine biosynthetic process|steroid metabolic process|cholesterol metabolic process|cholesterol metabolic process|cholesterol transport|very-low-density lipoprotein particle remodeling|high-density lipoprotein particle remodeling|cholesterol esterification|lipoprotein metabolic process|lipoprotein biosynthetic process|cholesterol homeostasis|reverse cholesterol transport|response to copper ion|response to glucocorticoid|regulation of high-density lipoprotein particle assembly|,"phosphatidylcholine-sterol O-acyltransferase activity|phosphatidylcholine-sterol O-acyltransferase activity|phospholipase A2 activity|O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|apolipoprotein A-I binding|",10,-0.6,5.95,10,-0.4,2.49,-0.5,8.04,-8.04,0.137,0,0,-1.2,-0.1
ENSMUSG00000036430,TBCC,tubulin-specific chaperone C,cytoplasm|photoreceptor connecting cilium|,cell morphogenesis|GTP catabolic process|post-chaperonin tubulin folding pathway|,GTPase activity|,6,0.9,6.42,7,1.1,2.11,0.9,8.01,8.01,0.138,0,0,0.5,1.9
ENSMUSG00000046876,ATXN1,ataxin 1,nucleus|nucleoplasm|cytoplasm|nuclear matrix|nuclear RNA export factor complex|nuclear inclusion body|nuclear inclusion body|intracellular membrane-bounded organelle|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|adult locomotory behavior|visual learning|negative regulation of phosphorylation|negative regulation of insulin-like growth factor receptor signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|lung alveolus development|nuclear export|regulation of excitatory postsynaptic membrane potential|",DNA binding|chromatin binding|RNA binding|protein binding|protein C-terminus binding|poly(U) RNA binding|poly(G) binding|identical protein binding|protein self-association|,10,-0.2,2.11,10,-0.5,7.02,-0.4,7.86,-7.86,0.141,0,0,-1.2,-0.1
ENSMUSG00000042747,KRTCAP2,keratinocyte associated protein 2,endoplasmic reticulum|oligosaccharyltransferase complex|membrane|integral component of membrane|,protein N-linked glycosylation via asparagine|,dolichyl-diphosphooligosaccharide-protein glycotransferase activity|,10,-0.5,7.93,10,-0.2,0.927,-0.4,7.85,-7.85,0.142,0,0,-1.2,-0.1
ENSMUSG00000027746,UFM1,ubiquitin-fold modifier 1,nucleus|cytoplasm|extracellular vesicular exosome|,response to endoplasmic reticulum stress|protein ufmylation|protein ufmylation|,molecular_function|,4,0.5,1.63,4,1.1,7.44,1,7.82,7.82,0.142,0,0,0.5,2
ENSMUSG00000034152,EXOC3,exocyst complex component 3,exocyst|cellular_component|,transport|exocytosis|biological_process|protein transport|,molecular_function|,10,-1.1,9.81,8,1.4,7.59,-0.3,7.66,-7.66,0.146,0,0,-2,2.2
ENSMUSG00000021891,METTL6,methyltransferase like 6,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-1.1,9.19,9,-0.2,0.472,-0.3,7.6,-7.6,0.147,0,0,-2,-0.1
ENSMUSG00000025757,HSPA4L,heat shock protein 4 like,nucleus|cytoplasm|cytosol|,protein folding|response to stress|response to unfolded protein|,nucleotide binding|protein binding|ATP binding|,10,-0.4,3.46,10,-0.4,4.48,-0.4,7.6,-7.6,0.147,0,0,-0.9,-0.1
ENSMUSG00000061311,RAG1,recombination activating gene 1,nucleus|nucleus|,adaptive immune response|pre-B cell allelic exclusion|pre-B cell allelic exclusion|DNA recombination|metabolic process|histone monoubiquitination|histone monoubiquitination|death|chromatin modification|B cell differentiation|B cell differentiation|B cell differentiation|T cell differentiation in thymus|T cell differentiation in thymus|V(D)J recombination|V(D)J recombination|V(D)J recombination|T cell homeostasis|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of T cell differentiation|thymus development|protein autoubiquitination|protein autoubiquitination|negative regulation of T cell apoptotic process|negative regulation of thymocyte apoptotic process|nucleic acid phosphodiester bond hydrolysis|nucleic acid phosphodiester bond hydrolysis|,"nucleic acid binding|DNA binding|catalytic activity|nuclease activity|endonuclease activity|endonuclease activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|hydrolase activity|hydrolase activity, acting on ester bonds|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|histone binding|histone binding|phosphoric ester hydrolase activity|protein homodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|T/G mismatch-specific endonuclease activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|retroviral 3' processing activity|metal ion binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1,4.13,10,0.9,3.88,1,7.58,7.58,0.148,0,0,0.5,1.9
ENSMUSG00000027722,SPATA5,spermatogenesis associated 5,cytoplasm|mitochondrion|,multicellular organismal development|spermatogenesis|cell differentiation|,nucleotide binding|ATP binding|,10,-0.6,5.75,10,1,4.17,-0.6,7.58,-7.58,0.148,0,0,-2,0.7
ENSMUSG00000025290,RPS24,ribosomal protein S24,intracellular|nucleus|nucleolus|cytoplasm|ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|,"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|rRNA processing|translation|translational elongation|erythrocyte homeostasis|ribosomal small subunit biogenesis|",nucleotide binding|structural constituent of ribosome|translation initiation factor binding|poly(A) RNA binding|,7,-0.4,2.15,8,1.2,6.83,1,7.56,7.56,0.148,0,0,0.2,2
ENSMUSG00000070284,GMPPB,GDP-mannose pyrophosphorylase B,cytoplasm|mitochondrion|,biosynthetic process|,nucleotide binding|mannose-1-phosphate guanylyltransferase activity|GTP binding|transferase activity|nucleotidyltransferase activity|,7,-0.1,0.0103,7,0.9,9.91,0.8,7.55,7.55,0.148,0,0,0.4,2
ENSMUSG00000069303,HIST1H2BR,histone cluster 1 H2br,nucleus|extracellular vesicular exosome|,biological_process|,molecular_function|,2,1.8,9.64,4,0.1,0.0927,1.8,7.54,7.54,0.148,0,0,0.6,3
ENSMUSG00000036840,SIAH1A,seven in absentia 1A,nucleus|cytoplasm|early endosome|cytosol|plasma membrane|beta-catenin destruction complex|,ubiquitin-dependent protein catabolic process|apoptotic process|cell cycle|male meiosis I|multicellular organismal development|spermatogenesis|post-embryonic development|protein ubiquitination|cell differentiation|protein catabolic process|protein destabilization|regulation of multicellular organism growth|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|neuron apoptotic process|positive regulation of intrinsic apoptotic signaling pathway|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|protein C-terminus binding|zinc ion binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,3.51,10,0.8,5.58,0.4,7.5,7.5,0.149,0,0,0.1,1.3
ENSMUSG00000006522,ITIH3,"inter-alpha trypsin inhibitor, heavy chain 3",extracellular region|,negative regulation of peptidase activity|hyaluronan metabolic process|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-1.1,9.63,10,0.8,4.56,-1,7.5,-7.5,0.149,0,0,-2,0.1
ENSMUSG00000027002,NCKAP1,NCK-associated protein 1,cytoplasm|plasma membrane|membrane|integral component of membrane|lamellipodium|SCAR complex|cell projection|extracellular vesicular exosome|,"in utero embryonic development|somitogenesis|neural tube closure|zygotic determination of anterior/posterior axis, embryo|endoderm development|mesodermal cell migration|embryonic body morphogenesis|positive regulation of lamellipodium assembly|Rac protein signal transduction|lamellipodium assembly|lamellipodium assembly|notochord development|establishment or maintenance of actin cytoskeleton polarity|regulation of protein localization|embryonic heart tube development|cell migration involved in gastrulation|basal protein localization|apical protein localization|paraxial mesoderm development|paraxial mesoderm morphogenesis|notochord morphogenesis|embryonic foregut morphogenesis|protein stabilization|positive regulation of Arp2/3 complex-mediated actin nucleation|",protein binding|protein complex binding|Rac GTPase binding|,10,0.2,0.748,10,1.5,10.1,1.4,7.49,7.49,0.15,0,0,0.2,2.9
ENSMUSG00000000631,MYO18A,myosin XVIIIA,Golgi membrane|cytoplasm|Golgi apparatus|trans-Golgi network|cytoskeleton|membrane|myosin complex|actomyosin|,Golgi organization|cell migration|actomyosin structure organization|Golgi vesicle budding|positive regulation of protein secretion|,nucleotide binding|motor activity|ATP binding|ADP binding|poly(A) RNA binding|actin filament binding|,10,0.5,3.77,10,0.4,4.03,0.5,7.47,7.47,0.15,0,0,0.1,1.1
ENSMUSG00000029111,NELFA,"negative elongation factor complex member A, Whsc2",nucleus|nucleus|cytoplasm|NELF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription elongation from RNA polymerase II promoter|",chromatin binding|,10,-0.8,8,9,0.5,2.32,-0.8,7.36,-7.36,0.153,0,0,-2,0.2
ENSMUSG00000000563,ATP5F1,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1","mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|membrane|proton-transporting ATP synthase complex, coupling factor F(o)|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|ATP synthesis coupled proton transport|proton transport|,"hydrogen ion transmembrane transporter activity|ATPase activity|proton-transporting ATP synthase activity, rotational mechanism|",10,0.5,4.43,10,0.7,3.4,0.6,7.31,7.31,0.154,0,0,0.1,1.4
ENSMUSG00000020493,PRR11,proline rich 11,cytoplasm|membrane|,biological_process|,molecular_function|,10,-0.4,2.5,10,-0.6,5.52,-0.5,7.3,-7.3,0.154,0,0,-1.3,-0.1
ENSMUSG00000032417,RWDD2A,RWD domain containing 2A,cellular_component|,biological_process|,molecular_function|,10,1.8,4.64,10,0.8,5.44,1.5,7.3,7.3,0.154,0,0,0.3,2.8
ENSMUSG00000029727,CYP3A13,"cytochrome P450, family 3, subfamily a, polypeptide 13",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,positive regulation of gene expression|oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|metal ion binding|aromatase activity|",10,0.5,6.02,10,0.4,1.73,0.5,7.2,7.2,0.157,0,0,0.1,1.2
ENSMUSG00000037075,RNF139,ring finger protein 139,endoplasmic reticulum|membrane|integral component of membrane|,negative regulation of cell proliferation|protein ubiquitination|negative regulation of translation|regulation of protein ubiquitination|regulation of ER to Golgi vesicle-mediated transport|regulation of protein processing|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|small conjugating protein ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.4,3.94,10,0.3,3.93,0.4,7.17,7.17,0.158,0,0,0.1,1
ENSMUSG00000095217,HIST1H2BN,"histone cluster 1, H2bn",nucleus|extracellular vesicular exosome|,biological_process|,molecular_function|,7,1.7,7.98,7,0.3,1.88,0.5,7.14,7.14,0.158,0,0,-0.8,3
ENSMUSG00000022325,POP1,"processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)",ribonuclease MRP complex|extracellular space|nucleolar ribonuclease P complex|,"tRNA catabolic process|RNA phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, endonucleolytic|",ribonuclease MRP activity|ribonuclease P activity|poly(A) RNA binding|,9,1.6,2.35,9,0.6,7.7,0.5,7.13,7.13,0.159,0,0,0.2,2.5
ENSMUSG00000032042,SRPR,signal recognition particle receptor ('docking protein'),endoplasmic reticulum|signal recognition particle receptor complex|membrane|extracellular vesicular exosome|,GTP catabolic process|SRP-dependent cotranslational protein targeting to membrane|transport|intracellular protein transport|,nucleotide binding|GTPase activity|signal recognition particle binding|GTP binding|poly(A) RNA binding|,9,-0.4,3.64,8,-0.7,3.96,-0.4,7.1,-7.1,0.159,0,0,-1.4,-0.1
ENSMUSG00000038717,ATP5L,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit G","mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|mitochondrial proton-transporting ATP synthase complex|extracellular vesicular exosome|",ATP catabolic process|ATP catabolic process|ATP synthesis coupled proton transport|ATP metabolic process|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|ATPase activity|",9,0.4,1.93,9,0.9,6.93,0.8,7.06,7.06,0.16,0,0,-1.4,2
ENSMUSG00000002320,TM9SF1,transmembrane 9 superfamily member 1,cellular_component|lysosome|membrane|integral component of membrane|cytoplasmic vesicle|,autophagy|biological_process|,molecular_function|,10,-0.4,3.95,10,-0.6,3.71,-0.5,7.04,-7.04,0.161,0,0,-1.3,-0.1
ENSMUSG00000020948,KLHL28,kelch-like 28,cellular_component|,biological_process|,molecular_function|,10,0.4,3.73,10,0.3,3.66,0.3,7.03,7.03,0.161,0,0,0.1,0.9
ENSMUSG00000061981,FLOT2,flotillin 2,acrosomal membrane|endosome|plasma membrane|caveola|caveola|membrane|membrane|flotillin complex|flotillin complex|endocytic vesicle|vesicle|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,cell adhesion|negative regulation of gene expression|protein stabilization|establishment of protein localization to plasma membrane|negative regulation of amyloid precursor protein catabolic process|,protease binding|ionotropic glutamate receptor binding|,10,0.6,4.11,10,0.5,3.51,0.6,7.03,7.03,0.161,0,0,0.1,1.3
ENSMUSG00000020183,CPM,carboxypeptidase M,plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,proteolysis|biological_process|,molecular_function|carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.9,4.91,10,0.8,9.47,0.8,6.96,6.96,0.163,0,0,-0.9,2
ENSMUSG00000025724,SEC11A,SEC11 homolog A (S. cerevisiae),endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,signal peptide processing|proteolysis|biological_process|,peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.5,3.38,10,0.5,3.91,0.5,6.96,6.96,0.163,0,0,0.1,1.4
ENSMUSG00000024359,HSPA9,heat shock protein 9,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial nucleoid|extracellular vesicular exosome|,protein folding|protein export from nucleus|,nucleotide binding|protein binding|ATP binding|fibroblast growth factor binding|enzyme binding|heat shock protein binding|poly(A) RNA binding|unfolded protein binding|,6,0.4,2.09,5,-0.7,8.25,-0.6,6.96,-6.96,0.163,0,0,-2,-0.1
ENSMUSG00000028982,SLC25A33,"solute carrier family 25, member 33",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|,None,10,0.5,3.61,10,0.5,3.58,0.5,6.86,6.86,0.166,0,0,-0.3,1.4
ENSMUSG00000035798,ZDHHC17,"zinc finger, DHHC domain containing 17",Golgi membrane|cytoplasm|Golgi apparatus|membrane|integral component of membrane|Golgi-associated vesicle membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|,transport|ion transport|signal transduction|magnesium ion transport|protein palmitoylation|protein palmitoylation|ion transmembrane transport|lipoprotein transport|positive regulation of I-kappaB kinase/NF-kappaB signaling|,"signal transducer activity|zinc ion binding|magnesium ion transmembrane transporter activity|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|identical protein binding|metal ion binding|",10,-0.3,1.44,10,-0.6,6.83,-0.5,6.83,-6.83,0.167,0,0,-1.5,-0.1
ENSMUSG00000064061,DZIP3,"DAZ interacting protein 3, zinc finger",cytoplasm|,protein polyubiquitination|,"RNA binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|phosphatase binding|polyubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,2.79,10,-0.5,4.56,-0.3,6.76,-6.76,0.169,0,0,-1.1,0.6
ENSMUSG00000052997,UBA2,ubiquitin-like modifier activating enzyme 2,nucleus|cytoplasm|cytosol|SUMO activating enzyme complex|,cellular protein modification process|protein sumoylation|protein sumoylation|SMT3-dependent protein catabolic process|,"nucleotide binding|catalytic activity|protein binding|ATP binding|transcription factor binding|small protein activating enzyme activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO activating enzyme activity|SUMO activating enzyme activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein heterodimerization activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.6,4.69,9,0.7,7.8,0.7,6.75,6.75,0.169,0,0,-0.6,2
ENSMUSG00000030659,NUCB2,nucleobindin 2,extracellular region|extracellular space|nucleus|nuclear outer membrane|cytoplasm|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|Golgi medial cisterna|membrane|extracellular vesicular exosome|,cellular calcium ion homeostasis|,DNA binding|tumor necrosis factor receptor binding|calcium ion binding|metal ion binding|,10,-0.5,0.515,10,-0.5,6.44,-0.5,6.73,-6.73,0.17,0,0,-1.5,-0.1
ENSMUSG00000068739,SARS,seryl-aminoacyl-tRNA synthetase,cytoplasm|mitochondrion|extracellular vesicular exosome|,translation|tRNA aminoacylation for protein translation|seryl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA ligase activity|serine-tRNA ligase activity|ATP binding|ligase activity|,9,-0.5,7.83,9,0,0,-0.5,6.72,-6.72,0.17,0,0,-1.4,-0.1
ENSMUSG00000040013,FKBP6,FK506 binding protein 6,synaptonemal complex|nucleus|chromosome|cytoplasm|endoplasmic reticulum membrane|cytosol|cytosol|membrane|,protein peptidyl-prolyl isomerization|protein folding|meiotic nuclear division|spermatogenesis|spermatogenesis|peptidyl-proline modification|cell differentiation|gene silencing by RNA|piRNA metabolic process|DNA methylation involved in gamete generation|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|Hsp90 protein binding|,10,-0.5,4.15,9,-0.8,2.91,-0.5,6.66,-6.66,0.172,0,0,-1.7,0.6
ENSMUSG00000022885,ST6GAL1,"beta galactoside alpha 2,6 sialyltransferase 1",extracellular region|Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|extracellular vesicular exosome|,N-acetylneuraminate metabolic process|protein glycosylation|protein N-linked glycosylation via asparagine|sialylation|sialylation|,"beta-galactoside alpha-2,6-sialyltransferase activity|beta-galactoside alpha-2,6-sialyltransferase activity|sialyltransferase activity|sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.8,0.121,10,1.4,7.37,1.2,6.66,6.66,0.172,0,0,0.5,2.9
ENSMUSG00000022185,ACIN1,apoptotic chromatin condensation inducer 1,nucleus|nucleus|nucleolus|cytoplasm|plasma membrane|nuclear speck|exon-exon junction complex|ASAP complex|,"mRNA processing|apoptotic process|RNA splicing|apoptotic chromosome condensation|positive regulation of apoptotic process|negative regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|poly(A) RNA binding|,10,0.5,1.83,10,1.4,7.7,1.3,6.65,6.65,0.172,0,0,0.1,2.7
ENSMUSG00000000826,DNAJC5,"DnaJ (Hsp40) homolog, subfamily C, member 5",mitochondrion|lysosomal membrane|plasma membrane|synaptic vesicle|membrane|membrane|extracellular vesicular exosome|,negative regulation of neuron apoptotic process|,glycoprotein binding|ATP-dependent protein binding|,10,0.4,4.18,10,0.4,2.75,0.4,6.61,6.61,0.173,0,0,0.1,1.1
ENSMUSG00000025266,GNL3L,guanine nucleotide binding protein-like 3 (nucleolar)-like,nucleus|nucleolus|nucleolus|cytoplasm|mitochondrion|membrane|,GTP catabolic process|ribosome biogenesis|,nucleotide binding|GTPase activity|GTP binding|poly(A) RNA binding|,10,-0.2,0.463,10,-0.6,7.07,-0.5,6.57,-6.57,0.174,0,0,-1.5,0.1
ENSMUSG00000020057,DRAM1,DNA-damage regulated autophagy modulator 1,cytoplasm|lysosome|membrane|integral component of membrane|,autophagy|apoptotic process|apoptotic nuclear changes|,molecular_function|,10,-0.8,1.17,10,-0.6,6.08,-0.6,6.56,-6.56,0.175,0,0,-1.6,0.2
ENSMUSG00000039318,RAB3GAP2,RAB3 GTPase activating protein subunit 2,cytoplasm|plasma membrane|,biological_process|regulation of GTPase activity|,molecular_function|GTPase activator activity|enzyme regulator activity|protein heterodimerization activity|,10,-0.2,0.382,10,-0.5,7.12,-0.5,6.46,-6.46,0.178,0,0,-1.3,0
ENSMUSG00000043411,USP48,ubiquitin specific peptidase 48,nucleus|cytoplasm|mitochondrion|membrane raft|postsynaptic membrane|,proteolysis|ubiquitin-dependent protein catabolic process|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0.6,8.08,10,-0.2,0.204,0.6,6.46,6.46,0.178,0,0,-0.3,1.5
ENSMUSG00000028639,YBX1,Y box protein 1,extracellular region|nucleus|nucleus|U12-type spliceosomal complex|cytoplasm|cytoplasm|cytoplasmic stress granule|dendrite|ribonucleoprotein complex|nuclear membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|extracellular vesicular exosome|CRD-mediated mRNA stability complex|histone pre-mRNA 3'end processing complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|positive regulation of cell proliferation|RNA splicing|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|negative regulation of insulin receptor signaling pathway|negative regulation of striated muscle cell differentiation|positive regulation of cell division|CRD-mediated mRNA stabilization|",p53 binding|nucleic acid binding|DNA binding|single-stranded DNA binding|single-stranded DNA binding|RNA binding|mRNA binding|protein binding|transcription factor binding|sequence-specific DNA binding|poly(A) RNA binding|,10,0.4,5.22,10,0.3,2.07,0.4,6.4,6.4,0.18,0,0,0,1
ENSMUSG00000034931,DHX8,DEAH (Asp-Glu-Ala-His) box polypeptide 8,nucleus|spliceosomal complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|identical protein binding|poly(A) RNA binding|,10,-0.4,2.15,10,-0.4,4.52,-0.4,6.37,-6.37,0.181,0,0,-1.2,0.6
ENSMUSG00000031622,SIN3B,"transcriptional regulator, SIN3B (yeast)",X chromosome|Y chromosome|XY body|nucleus|cytoplasm|autosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle tissue development|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|rhythmic process|cardiac muscle tissue development|",chromatin binding|transcription corepressor activity|protein binding|,10,0.6,4.32,10,0.6,2.34,0.6,6.35,6.35,0.181,0,0,0.1,1.6
ENSMUSG00000029125,STX18,syntaxin 18,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,SNAP receptor activity|,10,-0.7,4.48,9,-1.1,2.95,-0.8,6.28,-6.28,0.184,0,0,-2,0.9
ENSMUSG00000047879,USP14,ubiquitin specific peptidase 14,proteasome complex|cytoplasm|plasma membrane|cell surface|membrane|cytoplasmic membrane-bounded vesicle|synapse|,proteolysis|ubiquitin-dependent protein catabolic process|synaptic transmission|negative regulation of endopeptidase activity|protein deubiquitination|regulation of chemotaxis|regulation of proteasomal protein catabolic process|,ubiquitin thiolesterase activity|ubiquitin-specific protease activity|endopeptidase inhibitor activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|proteasome binding|,10,-0.4,3.42,10,-0.3,3.22,-0.4,6.25,-6.25,0.185,0,0,-1.2,0
ENSMUSG00000026727,RSU1,Ras suppressor protein 1,intracellular|extracellular vesicular exosome|,Ras protein signal transduction|positive regulation of neural precursor cell proliferation|,molecular_function|,10,-0.1,0.84,10,-1,8.71,-1,6.2,-6.2,0.187,0,0,-2,-0.3
ENSMUSG00000026289,ATG16L1,autophagy related 16-like 1 (S. cerevisiae),autophagic vacuole membrane|cytoplasm|autophagic vacuole|axoneme|membrane|,autophagic vacuole assembly|transport|autophagy|protein transport|negative stranded viral RNA replication|,protein binding|identical protein binding|,10,-0.9,4.99,10,-1.6,3.47,-1.4,6.18,-6.18,0.187,0,0,-3,1.2
ENSMUSG00000027466,RBCK1,RanBP-type and C3HC4-type zinc finger containing 1,LUBAC complex|,protein polyubiquitination|negative regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB import into nucleus|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of transcription from RNA polymerase II promoter|T cell receptor signaling pathway|positive regulation of NF-kappaB transcription factor activity|negative regulation of necroptotic process|protein linear polyubiquitination|positive regulation of extrinsic apoptotic signaling pathway|,"double-stranded DNA binding|ubiquitin-protein transferase activity|protein kinase C binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",8,-0.5,4.14,9,-0.9,2.81,-0.5,6.15,-6.15,0.188,0,0,-1.7,-0.1
ENSMUSG00000029050,SKI,ski sarcoma viral oncogene homolog (avian),nucleus|nucleus|transcription factor complex|cytoplasm|centrosome|nuclear body|PML body|transcriptional repressor complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|neural tube closure|lens morphogenesis in camera-type eye|transcription, DNA-templated|negative regulation of cell proliferation|anterior/posterior axis specification|negative regulation of Schwann cell proliferation|myotube differentiation|myotube differentiation|myotube differentiation|olfactory bulb development|myelination in peripheral nervous system|embryonic limb morphogenesis|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of histone deacetylation|negative regulation of activin receptor signaling pathway|somatic stem cell maintenance|regulation of apoptotic process|camera-type eye development|negative regulation of catalytic activity|positive regulation of DNA binding|nose morphogenesis|negative regulation of osteoblast differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of fibroblast proliferation|camera-type eye morphogenesis|skeletal muscle fiber development|palate development|retina development in camera-type eye|face morphogenesis|bone morphogenesis|SMAD protein signal transduction|protein homotrimerization|",chromatin binding|transcription corepressor activity|protein binding|zinc ion binding|protein kinase binding|protein domain specific binding|ubiquitin protein ligase binding|SMAD binding|SMAD binding|histone deacetylase inhibitor activity|repressing transcription factor binding|,10,0.1,0.493,10,0.4,6.97,0.4,6.14,6.14,0.189,0,0,0,1.1
ENSMUSG00000036372,TMEM258,transmembrane protein 258,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.9,8.18,10,0.2,1.01,-0.8,6.03,-6.03,0.193,0,0,-2,0.1
ENSMUSG00000030421,URI1,"URI1, prefoldin-like chaperone","nucleus|DNA-directed RNA polymerase II, core complex|cytoplasm|mitochondrion|prefoldin complex|cell projection|","negative regulation of transcription from RNA polymerase II promoter|regulation of cell growth|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein folding|response to virus|negative regulation of phosphatase activity|cellular response to growth factor stimulus|cellular response to steroid hormone stimulus|negative regulation of intrinsic apoptotic signaling pathway|",RNA polymerase II transcription corepressor activity|chromatin binding|protein phosphatase inhibitor activity|unfolded protein binding|,10,-0.9,6.57,9,0.3,2.59,-0.7,5.97,-5.97,0.195,0,0,-2,0.4
ENSMUSG00000032423,SYNCRIP,"synaptotagmin binding, cytoplasmic RNA interacting protein",nucleus|spliceosomal complex|cytoplasm|membrane|ribonucleoprotein complex|CRD-mediated mRNA stability complex|catalytic step 2 spliceosome|histone pre-mRNA 3'end processing complex|GAIT complex|,osteoblast differentiation|mRNA processing|RNA splicing|negative regulation of translation|CRD-mediated mRNA stabilization|cellular response to interferon-gamma|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) binding|poly(A) RNA binding|,10,0.7,7.39,10,0.2,0.533,0.6,5.97,5.97,0.195,0,0,0.1,1.6
ENSMUSG00000021963,SAP18,Sin3-associated polypeptide 18,histone deacetylase complex|nucleus|transcription factor complex|cytoplasm|nuclear speck|exon-exon junction complex|ASAP complex|,"regulation of alternative mRNA splicing, via spliceosome|regulation of transcription, DNA-templated|chromatin modification|positive regulation of apoptotic process|negative regulation of mRNA splicing, via spliceosome|",poly(A) RNA binding|,4,0.8,5.61,4,0.4,1.07,0.6,5.96,5.96,0.195,0,0,0.2,2
ENSMUSG00000032245,CLN6,"ceroid-lipofuscinosis, neuronal 6",nucleus|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|membrane|intracellular membrane-bounded organelle|,ganglioside metabolic process|ganglioside metabolic process|lysosome organization|lysosomal lumen acidification|lysosomal lumen acidification|visual perception|cholesterol metabolic process|cholesterol metabolic process|glycosaminoglycan metabolic process|glycosaminoglycan metabolic process|locomotion involved in locomotory behavior|cellular macromolecule catabolic process|positive regulation of proteolysis|positive regulation of proteolysis|,protein homodimerization activity|protein homodimerization activity|,10,0.5,3.65,10,0.5,2.54,0.5,5.88,5.88,0.199,0,0,0,1.4
ENSMUSG00000001441,NPEPPS,aminopeptidase puromycin sensitive,nucleus|cytoplasm|extracellular vesicular exosome|,proteolysis|cellular response to hypoxia|,aminopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.6,4.32,10,0.3,2.7,0.4,5.83,5.83,0.201,0,0,0,1.3
ENSMUSG00000075707,DIO3,"deiodinase, iodothyronine type III",endosome|plasma membrane|membrane|integral component of membrane|,positive regulation of multicellular organism growth|thyroid hormone catabolic process|hormone biosynthetic process|oxidation-reduction process|,thyroxine 5'-deiodinase activity|oxidoreductase activity|thyroxine 5-deiodinase activity|,10,-0.4,7.12,10,0.6,1.86,-0.3,5.75,-5.75,0.204,0,0,-1.1,0.9
ENSMUSG00000079547,H2-DMB1,"histocompatibility 2, class II, locus Mb1",lysosome|endosome|membrane|integral component of membrane|MHC class II protein complex|,immune system process|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|immune response|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|chaperone mediated protein folding requiring cofactor|,MHC class II protein complex binding|,10,-0.5,1.12,10,-0.9,5.83,-0.8,5.75,-5.75,0.204,0,0,-1.9,-0.2
ENSMUSG00000038175,MYLIP,myosin regulatory light chain interacting protein,intracellular|cytoplasm|cytoskeleton|plasma membrane|membrane|extrinsic component of membrane|,cellular component movement|nervous system development|negative regulation of low-density lipoprotein particle clearance|protein ubiquitination|protein ubiquitination|protein destabilization|regulation of low-density lipoprotein particle receptor catabolic process|cholesterol homeostasis|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of protein catabolic process|response to low-density lipoprotein particle|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|cytoskeletal protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,3.94,10,-0.3,2.09,-0.3,5.74,-5.74,0.205,0,0,-1,0.1
ENSMUSG00000024750,ZFAND5,"zinc finger, AN1-type domain 5",cytoplasm|,in utero embryonic development|vasculature development|respiratory system process|fibroblast migration|platelet-derived growth factor receptor signaling pathway|skeletal system morphogenesis|smooth muscle tissue development|face development|,DNA binding|zinc ion binding|metal ion binding|,10,0.4,3.4,10,1.2,6.27,1.1,5.73,5.73,0.205,0,0,-1,2
ENSMUSG00000048007,TIMM8A1,translocase of inner mitochondrial membrane 8A1,mitochondrion|mitochondrion|mitochondrial intermembrane space|,protein targeting to mitochondrion|,zinc ion binding|,4,-0.5,2.17,4,-0.6,3.85,-0.6,5.72,-5.72,0.205,0,0,-2,-0.1
ENSMUSG00000071715,NCF4,neutrophil cytosolic factor 4,cytoplasm|endosome|cytosol|endosome membrane|membrane|NADPH oxidase complex|,positive regulation of catalytic activity|,protein binding|lipid binding|superoxide-generating NADPH oxidase activator activity|phosphatidylinositol-3-phosphate binding|phosphatidylinositol binding|,10,0.7,4.19,10,0.3,3.15,0.4,5.69,5.69,0.207,0,0,0,1.5
ENSMUSG00000034278,DNAJC17,"DnaJ (Hsp40) homolog, subfamily C, member 17",nucleus|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|,nucleotide binding|RNA binding|,10,0.5,3.77,10,0.4,2.26,0.5,5.68,5.68,0.207,0,0,-0.9,1.4
ENSMUSG00000023236,SCG5,secretogranin V,extracellular region|intracellular|cell|secretory granule|,transport|intracellular protein transport|neuropeptide signaling pathway|peptide hormone processing|negative regulation of catalytic activity|regulation of hormone secretion|,enzyme inhibitor activity|unfolded protein binding|,10,0,0,10,0.6,7.07,0.5,5.66,5.66,0.208,0,0,-0.1,1.5
ENSMUSG00000022205,SUB1,SUB1 homolog (S. cerevisiae),nucleus|transcription factor complex|nucleolus|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|SMAD protein signal transduction|",RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|single-stranded DNA binding|transcription coactivator activity|poly(A) RNA binding|,10,0.4,1.94,9,0.5,4.04,0.4,5.6,5.6,0.21,0,0,0,1.3
ENSMUSG00000040681,HMGN1,high mobility group nucleosomal binding domain 1,chromatin|nucleus|nucleus|cytoplasm|,"pyrimidine dimer repair by nucleotide-excision repair|transcription-coupled nucleotide-excision repair|chromatin organization|regulation of transcription from RNA polymerase II promoter|response to UV-B|response to UV-C|regulation of development, heterochronic|post-embryonic camera-type eye morphogenesis|regulation of epithelial cell proliferation|",DNA binding|chromatin binding|nucleosomal DNA binding|,10,0.4,2.36,10,0.5,3.68,0.5,5.56,5.56,0.212,0,0,0,1.3
ENSMUSG00000036030,PRTG,protogenin homolog (Gallus gallus),extracellular space|membrane|integral component of membrane|,multicellular organismal development|,None,10,0.6,5.45,10,-0.4,3.48,0.5,5.48,5.48,0.216,0,0,-0.8,1.3
ENSMUSG00000040857,ERF,Ets2 repressor factor,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|ectodermal cell differentiation|trophoblast giant cell differentiation|chorio-allantoic fusion|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|sequence-specific DNA binding|,10,0.3,1.75,10,0.5,4.09,0.4,5.43,5.43,0.218,0,0,-0.1,1.2
ENSMUSG00000020794,UBE2G1,ubiquitin-conjugating enzyme E2G 1,extracellular vesicular exosome|,protein K63-linked ubiquitination|protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|ubiquitin protein ligase binding|,10,0.6,3.58,10,0.3,2.7,0.4,5.42,5.42,0.218,0,0,0,1.3
ENSMUSG00000025893,KBTBD3,kelch repeat and BTB (POZ) domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0.6,2.56,10,0.5,3.13,0.5,5.38,5.38,0.22,0,0,-0.1,1.4
ENSMUSG00000002332,DHRS1,dehydrogenase/reductase (SDR family) member 1,mitochondrion|mitochondrial inner membrane|endoplasmic reticulum|,biological_process|metabolic process|oxidation-reduction process|,"molecular_function|oxidoreductase activity|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|versicolorin reductase activity|ketoreductase activity|",10,-0.5,1.45,10,-0.6,4.33,-0.6,5.36,-5.36,0.221,0,0,-1.5,1.1
ENSMUSG00000010080,EPN3,epsin 3,nucleus|cytoplasm|coated pit|extrinsic component of plasma membrane|clathrin-coated vesicle|cytoplasmic vesicle|perinuclear region of cytoplasm|extracellular vesicular exosome|,biological_process|,lipid binding|EH domain binding|,10,0.4,2.11,10,0.4,3.44,0.4,5.26,5.26,0.226,0,0,-0.2,1.1
ENSMUSG00000079480,PIN4,"protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)",nucleus|nucleolus|cytoplasm|mitochondrial matrix|spindle|cytoskeleton|preribosome|extracellular vesicular exosome|,rRNA processing|protein folding|,DNA binding|bent DNA binding|double-stranded DNA binding|peptidyl-prolyl cis-trans isomerase activity|isomerase activity|poly(A) RNA binding|,10,-0.4,3.41,10,0.5,7.27,0.5,5.26,5.26,0.226,0,0,-0.9,1.4
ENSMUSG00000026775,YME1L1,YME1-like 1 (S. cerevisiae),mitochondrion|mitochondrial inner membrane|membrane|membrane|integral component of membrane|,proteolysis|misfolded or incompletely synthesized protein catabolic process|mitochondrion organization|cell proliferation|,nucleotide binding|metalloendopeptidase activity|ATP binding|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.8,7.99,10,0,0,0.8,5.24,5.24,0.227,0,0,-0.2,1.8
ENSMUSG00000028696,IPP,IAP promoted placental gene,cytoplasm|cytoskeleton|,None,actin binding|,10,0.5,4.36,10,-1.2,1.82,0.4,5.22,5.22,0.228,0,0,-1.1,1.8
ENSMUSG00000002204,NAPSA,napsin A aspartic peptidase,extracellular region|extracellular space|lysosome|lysosome|extracellular vesicular exosome|alveolar lamellar body|alveolar lamellar body|,proteolysis|membrane protein proteolysis|membrane protein proteolysis|surfactant homeostasis|,"endopeptidase activity|endopeptidase activity|aspartic-type endopeptidase activity|protein binding|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|",10,1.7,8.41,10,-0.1,0.525,1.6,5.22,5.22,0.228,0,0,-0.1,3
ENSMUSG00000032562,GNAI2,"guanine nucleotide binding protein (G protein), alpha inhibiting 2",nucleus|cytoplasm|centrosome|cytosol|heterotrimeric G-protein complex|cytoskeleton|plasma membrane|membrane|midbody|membrane raft|extracellular vesicular exosome|,activation of MAPKK activity|adenosine receptor signaling pathway|adenosine receptor signaling pathway|GTP catabolic process|cell cycle|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|G-protein coupled acetylcholine receptor signaling pathway|gamma-aminobutyric acid signaling pathway|gamma-aminobutyric acid signaling pathway|cell proliferation|positive regulation of cell proliferation|intracellular signal transduction|negative regulation of synaptic transmission|cell division|regulation of calcium ion transport|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|signal transducer activity|protein binding|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,0.8,5.45,10,-0.3,1.69,0.7,5.22,5.22,0.228,0,0,-0.3,1.7
ENSMUSG00000040204,2810417H13RIK,RIKEN cDNA 2810417H13 gene,nucleus|cytoplasm|perinuclear region of cytoplasm|,DNA replication|DNA repair|cellular response to DNA damage stimulus|response to UV|translesion synthesis|centrosome organization|regulation of cell cycle|,chromatin binding|,10,1,2.95,10,0.5,3.97,0.7,5.18,5.18,0.23,0,0,-0.2,1.8
ENSMUSG00000025786,ZDHHC3,"zinc finger, DHHC domain containing 3",Golgi apparatus|Golgi apparatus|membrane|membrane|integral component of membrane|,protein targeting|protein palmitoylation|protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,-0.4,3,10,-0.3,2.65,-0.3,5.18,-5.18,0.23,0,0,-1.2,0.1
ENSMUSG00000042626,SHC1,src homology 2 domain-containing transforming protein C1,nucleus|cytoplasm|mitochondrion|plasma membrane|endosome membrane|Shc-EGFR complex|,MAPK cascade|activation of MAPK activity|activation of MAPK activity|angiogenesis|heart development|aging|insulin receptor signaling pathway|single organismal cell-cell adhesion|actin cytoskeleton organization|neuron differentiation|neuron projection development|actin cytoskeleton reorganization|intracellular signal transduction|regulation of growth|positive regulation of DNA replication|positive regulation of vasoconstriction|positive regulation of smooth muscle cell proliferation|,phosphotyrosine binding|epidermal growth factor receptor binding|insulin receptor binding|insulin-like growth factor receptor binding|neurotrophin TRKA receptor binding|protein binding|receptor tyrosine kinase binding|receptor tyrosine kinase binding|protein complex binding|ephrin receptor binding|ephrin receptor binding|phosphoprotein binding|,10,-0.5,4.31,10,-0.3,1.27,-0.5,5.16,-5.16,0.231,0,0,-1.4,0.3
ENSMUSG00000045140,PIGW,"phosphatidylinositol glycan anchor biosynthesis, class W",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,GPI anchor biosynthetic process|,"transferase activity|transferase activity, transferring acyl groups|",10,-0.4,5.32,10,-0.2,0.421,-0.3,5.14,-5.14,0.232,0,0,-1.1,0.2
ENSMUSG00000010110,STX5A,syntaxin 5A,Golgi membrane|Golgi membrane|nucleus|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|SNARE complex|,"transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|vesicle-mediated transport|retrograde transport, endosome to Golgi|vesicle fusion with Golgi apparatus|",SNAP receptor activity|protein N-terminus binding|,8,0.7,7.2,8,0.1,0.148,0.7,5.12,5.12,0.233,0,0,0,1.8
ENSMUSG00000073676,HSPE1,heat shock protein 1 (chaperonin 10),cytoplasm|mitochondrion|mitochondrion|mitochondrial matrix|membrane|extracellular vesicular exosome|,osteoblast differentiation|protein folding|response to stress|,ATP binding|poly(A) RNA binding|chaperone binding|,5,-0.9,6.8,4,0.1,0.0209,-0.8,5.06,-5.06,0.236,0,0,-2,1.8
ENSMUSG00000050468,ASTL,astacin-like metalloendopeptidase (M12 family),None,proteolysis|proteolysis|,metalloendopeptidase activity|peptidase activity|,10,-0.2,1.19,10,-0.7,5.35,-0.4,4.99,-4.99,0.24,0,0,-1.4,0
ENSMUSG00000032525,NKTR,natural killer tumor recognition sequence,None,protein peptidyl-prolyl isomerization|protein folding|,peptidyl-prolyl cis-trans isomerase activity|isomerase activity|peptide binding|,10,0.4,3.1,10,0.4,2.17,0.4,4.99,4.99,0.24,0,0,-0.7,1.2
ENSMUSG00000068114,CCDC134,coiled-coil domain containing 134,extracellular region|membrane|,biological_process|,molecular_function|,10,0.6,4.89,10,0.3,1.06,0.5,4.99,4.99,0.24,0,0,-0.5,1.6
ENSMUSG00000000787,DDX3X,"DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked",nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|eukaryotic translation initiation factor 3 complex|cytoplasmic stress granule|membrane|cytosolic small ribosomal subunit|extracellular vesicular exosome|,"immune system process|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|apoptotic process|chromosome segregation|extrinsic apoptotic signaling pathway via death domain receptors|response to virus|RNA secondary structure unwinding|negative regulation of translation|positive regulation of cell growth|negative regulation of cell growth|negative regulation of protein complex assembly|DNA duplex unwinding|stress granule assembly|intracellular signal transduction|ribosome biogenesis|mature ribosome assembly|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|innate immune response|positive regulation of translation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of translational initiation|cellular response to arsenic-containing substance|cellular response to osmotic stress|intrinsic apoptotic signaling pathway|positive regulation of G1/S transition of mitotic cell cycle|negative regulation of intrinsic apoptotic signaling pathway|",nucleotide binding|nucleic acid binding|DNA binding|RNA binding|ATP-dependent DNA helicase activity|ATP-dependent RNA helicase activity|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|transcription factor binding|poly(A) binding|eukaryotic initiation factor 4E binding|hydrolase activity|ATPase activity|translation initiation factor binding|RNA stem-loop binding|ribosomal small subunit binding|poly(A) RNA binding|mRNA 5'-UTR binding|,10,-0.7,4.36,9,0.7,6.31,0.6,4.99,4.99,0.24,0,0,-1.4,1.6
ENSMUSG00000034120,SRSF2,serine/arginine-rich splicing factor 2,nucleus|nucleus|spliceosomal complex|nuclear speck|nuclear speck|extracellular vesicular exosome|,mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|protein binding|poly(A) RNA binding|,7,0.5,3.4,7,0.4,1.94,0.4,4.98,4.98,0.24,0,0,-0.3,1.5
ENSMUSG00000033386,FRRS1,ferric-chelate reductase 1,membrane|integral component of membrane|,transport|oxidation-reduction process|,ferric-chelate reductase activity|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|epoxyqueuosine reductase activity|,10,-0.2,1.13,10,-0.5,4.66,-0.3,4.94,-4.94,0.243,0,0,-1.2,0.3
ENSMUSG00000020609,APOB,apolipoprotein B,extracellular region|extracellular space|cytoplasm|endoplasmic reticulum|Golgi apparatus|plasma membrane|vesicle membrane|actin cytoskeleton|vesicle lumen|mature chylomicron|very-low-density lipoprotein particle|low-density lipoprotein particle|intermediate-density lipoprotein particle|chylomicron|intracellular membrane-bounded organelle|,in utero embryonic development|lipid metabolic process|lipid metabolic process|lipid metabolic process|lipid metabolic process|triglyceride mobilization|transport|lipid transport|spermatogenesis|nervous system development|steroid metabolic process|cholesterol metabolic process|fertilization|response to carbohydrate|post-embryonic development|positive regulation of macrophage derived foam cell differentiation|positive regulation of lipid storage|positive regulation of cholesterol storage|lipid catabolic process|triglyceride catabolic process|triglyceride catabolic process|cholesterol transport|cholesterol transport|sperm motility|cholesterol efflux|low-density lipoprotein particle remodeling|low-density lipoprotein particle clearance|lipoprotein metabolic process|lipoprotein metabolic process|lipoprotein biosynthetic process|lipoprotein catabolic process|cholesterol homeostasis|cholesterol homeostasis|cholesterol homeostasis|lipoprotein transport|lipoprotein transport|regulation of cholesterol biosynthetic process|artery morphogenesis|,lipid transporter activity|phospholipid binding|heparin binding|lipid binding|cholesterol transporter activity|lipase binding|low-density lipoprotein particle receptor binding|,10,0.7,2.14,10,0.5,3.17,0.6,4.94,4.94,0.243,0,0,-0.2,1.6
ENSMUSG00000018574,ACADVL,"acyl-Coenzyme A dehydrogenase, very long chain",nucleus|nucleolus|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|mitochondrial nucleoid|,temperature homeostasis|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|metabolic process|fatty acid beta-oxidation using acyl-CoA dehydrogenase|fatty acid beta-oxidation using acyl-CoA dehydrogenase|very long-chain fatty acid catabolic process|negative regulation of fatty acid biosynthetic process|negative regulation of fatty acid oxidation|oxidation-reduction process|regulation of cholesterol metabolic process|,"fatty-acyl-CoA binding|acyl-CoA dehydrogenase activity|long-chain-acyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|very-long-chain-acyl-CoA dehydrogenase activity|flavin adenine dinucleotide binding|",10,0.4,3.23,10,0.3,1.99,0.4,4.9,4.9,0.245,0,0,-0.1,1.3
ENSMUSG00000006007,PDC,phosducin,photoreceptor outer segment|nucleus|cytoplasm|cytosol|cilium|cell projection|,visual perception|response to stimulus|,None,10,0.5,1.04,10,0.4,4.2,0.5,4.89,4.89,0.245,0,0,-0.2,1.4
ENSMUSG00000025473,ADAM8,a disintegrin and metallopeptidase domain 8,podosome|podosome|cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|phagolysosome|dense core granule membrane|specific granule|tertiary granule|alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex|alpha9-beta1 integrin-ADAM8 complex|,cell morphogenesis|angiogenesis|leukocyte migration involved in inflammatory response|positive regulation of acute inflammatory response|positive regulation of cellular extravasation|proteolysis|inflammatory response|cell-matrix adhesion|integrin-mediated signaling pathway|single organismal cell-cell adhesion|regulation of cell-cell adhesion|positive regulation of T cell differentiation in thymus|activation of MAPK activity involved in innate immune response|negative regulation of neuron apoptotic process|blood vessel endothelial cell migration|regulation of osteoclast differentiation|positive regulation of bone resorption|positive regulation of bone resorption|positive regulation of cell adhesion|lymphocyte chemotaxis|tissue morphogenesis|positive regulation of inflammatory response|positive regulation of membrane protein ectodomain proteolysis|positive regulation of membrane protein ectodomain proteolysis|positive regulation of NF-kappaB transcription factor activity|positive regulation of protein kinase B signaling|membrane fusion|positive regulation of thymocyte apoptotic process|cellular response to hypoxia|osteoclast fusion|positive regulation of tumor necrosis factor (ligand) superfamily member 11 production|positive regulation of neutrophil extravasation|negative regulation of thymocyte aggregation|positive regulation of T cell migration|positive regulation of fibronectin-dependent thymocyte migration|positive regulation of eosinophil migration|,metalloendopeptidase activity|integrin binding|calcium ion binding|protein binding|peptidase activity|metallopeptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|cell adhesion molecule binding|cell adhesion molecule binding|,10,-0.4,4.93,10,-0.7,0.254,-0.4,4.86,-4.86,0.247,0,0,-1.5,0.3
ENSMUSG00000059263,USP47,ubiquitin specific peptidase 47,cytoplasm|SCF ubiquitin ligase complex|SCF ubiquitin ligase complex|,"DNA repair|base-excision repair|proteolysis|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|negative regulation of G2/M transition of mitotic cell cycle|negative regulation of G2/M transition of mitotic cell cycle|positive regulation of cell growth|positive regulation of cell growth|cellular response to UV|monoubiquitinated protein deubiquitination|response to drug|response to drug|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|",ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|WD40-repeat domain binding|,10,-0.7,0.628,10,-0.6,4.47,-0.7,4.85,-4.85,0.247,0,0,-1.7,0.3
ENSMUSG00000035186,UBD,ubiquitin D,nucleus|nucleus|cytoplasm|aggresome|,ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|protein ubiquitination|protein ubiquitination|protein modification by small protein conjugation|myeloid dendritic cell differentiation|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|aggresome assembly|,protein binding|proteasome binding|,10,-1,4.26,10,-0.9,0.921,-1,4.83,-4.83,0.249,0,0,-2,0.4
ENSMUSG00000051437,UBQLNL,ubiquilin-like,cellular_component|,biological_process|,molecular_function|,10,-0.4,2.32,10,-0.4,2.79,-0.4,4.83,-4.83,0.249,0,0,-1.2,0.2
ENSMUSG00000021218,GDI2,guanosine diphosphate (GDP) dissociation inhibitor 2,cytoplasm|Golgi apparatus|membrane|extracellular vesicular exosome|,small GTPase mediated signal transduction|protein transport|positive regulation of Rab GTPase activity|regulation of catalytic activity|,Rab GDP-dissociation inhibitor activity|GTPase activator activity|Rab GTPase activator activity|small GTPase binding|poly(A) RNA binding|,10,1.5,1.79,10,0.9,4.11,1.2,4.77,4.77,0.252,0,0,0.1,2.7
ENSMUSG00000014349,UBE2Z,ubiquitin-conjugating enzyme E2Z (putative),nucleus|cytoplasm|,apoptotic process|biological_process|,nucleotide binding|molecular_function|ATP binding|ligase activity|acid-amino acid ligase activity|,10,-0.4,2.09,10,-1.1,4.8,-0.7,4.76,-4.76,0.253,0,0,-2,-0.1
ENSMUSG00000023966,RSPH9,radial spoke head 9 homolog (Chlamydomonas),cytoplasm|cytoskeleton|cilium|axoneme|motile cilium|cell projection|,cilium movement|cilium movement|axoneme assembly|axoneme assembly|,molecular_function|,10,0.5,2.06,10,0.5,2.97,0.5,4.75,4.75,0.253,0,0,-0.1,1.5
ENSMUSG00000041571,SEPW1,"selenoprotein W, muscle 1",cytoplasm|plasma membrane|,cell redox homeostasis|oxidation-reduction process|,selenium binding|antioxidant activity|oxidoreductase activity|,10,0.3,1.13,10,0.5,3.97,0.4,4.74,4.74,0.254,0,0,-0.2,1.3
ENSMUSG00000033545,ZNRF1,zinc and ring finger 1,lysosome|endosome|cytosol|membrane|cell junction|cytoplasmic vesicle|synapse|,cytoskeleton organization|protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|protein K48-linked ubiquitination|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,2.82,10,-0.3,2.17,-0.3,4.72,-4.72,0.255,0,0,-1,0.2
ENSMUSG00000029798,HERC6,hect domain and RLD 6,nucleus|nucleus|cytoplasm|cytoplasm|,hematopoietic progenitor cell differentiation|immune system process|protein ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|innate immune response|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|cyclin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,2.41,10,-0.3,2.68,-0.3,4.69,-4.69,0.257,0,0,-1.4,0.5
ENSMUSG00000019715,GLE1,GLE1 RNA export mediator (yeast),extracellular space|nucleus|nuclear pore|cytoplasm|plasma membrane|membrane|,transport|protein transport|poly(A)+ mRNA export from nucleus|mRNA transport|,identical protein binding|,10,0.4,3.45,10,0.5,1.5,0.4,4.68,4.68,0.257,0,0,-0.7,1.4
ENSMUSG00000021902,PHF7,PHD finger protein 7,nucleus|Golgi apparatus|plasma membrane|,biological_process|,zinc ion binding|metal ion binding|,10,0.1,0.332,10,0.6,6.1,0.4,4.67,4.67,0.258,0,0,-2.1,1.8
ENSMUSG00000027188,PAMR1,peptidase domain containing associated with muscle regeneration 1,extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|,10,-0.5,3.93,10,-0.8,1.19,-0.5,4.66,-4.66,0.258,0,0,-1.7,0.3
ENSMUSG00000060373,HNRNPC,heterogeneous nuclear ribonucleoprotein C,nuclear chromatin|nucleus|nucleus|spliceosomal complex|cytosol|membrane|ribonucleoprotein complex|protein complex|pronucleus|extracellular vesicular exosome|catalytic step 2 spliceosome|,osteoblast differentiation|mRNA processing|RNA splicing|ATP-dependent chromatin remodeling|3'-UTR-mediated mRNA stabilization|,nucleotide binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|nucleic acid binding|RNA binding|mRNA binding|mRNA 3'-UTR binding|poly(U) RNA binding|nucleosomal DNA binding|identical protein binding|poly(A) RNA binding|,6,-0.6,2.76,7,0.8,6.76,0.8,4.64,4.64,0.259,0,0,-0.8,2
ENSMUSG00000028603,SCP2,"sterol carrier protein 2, liver",nucleus|cytoplasm|mitochondrion|peroxisome|peroxisome|membrane|intracellular membrane-bounded organelle|protein complex|extracellular vesicular exosome|,acyl-CoA metabolic process|steroid biosynthetic process|progesterone biosynthetic process|transport|lipid transport|peroxisome organization|metabolic process|positive regulation of steroid biosynthetic process|phospholipid transport|positive regulation of intracellular cholesterol transport|inositol trisphosphate biosynthetic process|positive regulation of steroid metabolic process|protein localization to plasma membrane|lipid hydroperoxide transport|,"fatty-acyl-CoA binding|catalytic activity|receptor binding|protein binding|lipid binding|phosphatidylinositol transporter activity|cholesterol binding|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|propanoyl-CoA C-acyltransferase activity|long-chain fatty acyl-CoA binding|propionyl-CoA C2-trimethyltridecanoyltransferase activity|oleic acid binding|",10,0.4,2.22,10,0.5,2.76,0.5,4.63,4.63,0.26,0,0,-0.1,1.5
ENSMUSG00000055681,COPE,"coatomer protein complex, subunit epsilon",nucleus|cytoplasm|Golgi apparatus|membrane|COPI-coated vesicle|cytoplasmic vesicle|,"transport|retrograde vesicle-mediated transport, Golgi to ER|protein transport|vesicle-mediated transport|",structural molecule activity|,9,1.1,5.47,9,0.4,1.3,0.9,4.62,4.62,0.261,0,0,0,2
ENSMUSG00000000439,MKRN2,"makorin, ring finger protein, 2",intracellular|intracellular|,biological_process|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-1,1.31,10,1,3.57,1,4.58,4.58,0.263,0,0,-0.2,2
ENSMUSG00000068874,SELENBP1,selenium binding protein 1,extracellular space|nucleus|cytoplasm|membrane|extracellular vesicular exosome|,transport|protein transport|brown fat cell differentiation|,selenium binding|,10,-0.4,4.29,10,-0.2,1.13,-0.3,4.56,-4.56,0.264,0,0,-1.3,0.3
ENSMUSG00000071226,CECR2,"cat eye syndrome chromosome region, candidate 2",nucleus|nuclear euchromatin|ISWI-type complex|CERF complex|,neural fold formation|neural tube closure|neural tube closure|single fertilization|neural tube development|ATP-dependent chromatin remodeling|inner ear receptor stereocilium organization|cochlea development|execution phase of apoptosis|,molecular_function|,10,-0.4,2.17,10,0.6,5.97,0.6,4.55,4.55,0.265,0,0,-1.1,1.5
ENSMUSG00000057143,TRIM12C,tripartite motif-containing 12C,cytoplasmic mRNA processing body|nucleus|cytoplasm|Golgi apparatus|,pattern recognition receptor signaling pathway|protein ubiquitination|,ubiquitin-protein transferase activity|signaling pattern recognition receptor activity|identical protein binding|protein homodimerization activity|metal ion binding|,10,-0.5,4.88,10,0.7,0.553,-0.4,4.52,-4.52,0.267,0,0,-1.4,0.9
ENSMUSG00000037326,CAPN15,calpain 15,intracellular|cytoplasm|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.2,0.834,10,0.5,4.89,0.4,4.45,4.45,0.271,0,0,-0.1,1.4
ENSMUSG00000056629,FKBP2,FK506 binding protein 2,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|extracellular vesicular exosome|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|isomerase activity|,10,0.1,0.16,10,1,6.27,0.9,4.44,4.44,0.272,0,0,0.1,1.9
ENSMUSG00000039630,HNRNPU,heterogeneous nuclear ribonucleoprotein U,nucleus|spliceosomal complex|cytoplasm|membrane|virion|viral nucleocapsid|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|CRD-mediated mRNA stability complex|catalytic step 2 spliceosome|,osteoblast differentiation|mRNA processing|RNA splicing|CRD-mediated mRNA stabilization|,nucleotide binding|nucleic acid binding|DNA binding|RNA binding|protein binding|ATP binding|poly(A) RNA binding|,8,-0.6,4.4,7,0.5,3.06,-0.6,4.4,-4.4,0.274,0,0,-1.5,1.6
ENSMUSG00000063317,USP31,ubiquitin specific peptidase 31,nucleus|,proteolysis|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,8,0.8,4.01,8,0.4,1.38,0.6,4.36,4.36,0.277,0,0,-0.1,1.8
ENSMUSG00000033382,TRAPPC8,trafficking protein particle complex 8,cellular_component|,biological_process|,molecular_function|,9,1.5,5.31,9,0.2,1.47,0.4,4.36,4.36,0.277,0,0,0,2.7
ENSMUSG00000001576,ERGIC1,endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1,endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|membrane|integral component of membrane|,transport|ER to Golgi vesicle-mediated transport|vesicle-mediated transport|,molecular_function|,10,-0.4,2.37,10,0.7,4.41,-0.5,4.33,-4.33,0.279,0,0,-1.5,1.4
ENSMUSG00000044664,PRSS42,"protease, serine 42",extracellular region|cytoplasm|anchored component of plasma membrane|,proteolysis|germ cell development|spermatogenesis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.4,5.69,10,-0.1,0.0419,-0.3,4.33,-4.33,0.279,0,0,-1.3,0.3
ENSMUSG00000018567,GABARAP,gamma-aminobutyric acid receptor associated protein,autophagic vacuole membrane|cytoplasm|lysosome|autophagic vacuole|smooth endoplasmic reticulum|Golgi apparatus|cytoskeleton|microtubule|microtubule associated complex|plasma membrane|axoneme|actin cytoskeleton|membrane|cytoplasmic vesicle|cell body|perinuclear region of cytoplasm|,microtubule cytoskeleton organization|transport|autophagy|apoptotic process|extrinsic apoptotic signaling pathway via death domain receptors|protein transport|,protein binding|microtubule binding|beta-tubulin binding|GABA receptor binding|,10,0.4,3.66,10,0.2,1.42,0.3,4.28,4.28,0.282,0,0,-0.4,1.2
ENSMUSG00000020640,ITSN2,intersectin 2,cytoplasm|extracellular vesicular exosome|,endocytosis|regulation of Rho protein signal transduction|,Rho guanyl-nucleotide exchange factor activity|calcium ion binding|protein binding|metal ion binding|,10,0.6,2.78,10,0.3,2.12,0.4,4.26,4.26,0.284,0,0,-0.4,1.5
ENSMUSG00000030873,SCNN1B,"sodium channel, nonvoltage-gated 1 beta",plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|sodium channel complex|sodium channel complex|extracellular vesicular exosome|,"regulation of sodium ion transport|transport|ion transport|sodium ion transport|sodium ion transport|sodium ion transport|wound healing, spreading of epidermal cells|sodium ion transmembrane transport|sodium ion transmembrane transport|multicellular organismal water homeostasis|response to stimulus|sensory perception of taste|sodium ion homeostasis|",sodium channel activity|protein binding|ligand-gated sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|WW domain binding|WW domain binding|,10,-0.4,5.6,10,0,0,-0.3,4.25,-4.25,0.284,0,0,-1.3,0.2
ENSMUSG00000042790,RNF214,ring finger protein 214,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.5,2.21,10,1.3,4.82,1.1,4.23,4.23,0.286,0,0,-0.2,2
ENSMUSG00000031930,WWP2,WW domain containing E3 ubiquitin protein ligase 2,nucleus|nucleus|cytoplasm|membrane|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of gene expression|protein ubiquitination|protein ubiquitination|negative regulation of transporter activity|regulation of ion transmembrane transport|regulation of membrane potential|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|negative regulation of protein transport|protein autoubiquitination|protein K63-linked ubiquitination|regulation of potassium ion transmembrane transporter activity|","RNA polymerase II transcription factor binding|RNA polymerase II transcription factor binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|transcription factor binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.5,4.8,10,-1,1.85,0.4,4.22,4.22,0.286,0,0,-1.4,1.3
ENSMUSG00000029253,CENPC1,centromere protein C1,"chromosome, centromeric region|kinetochore|condensed nuclear chromosome, centromeric region|nucleus|chromosome|centromeric heterochromatin|cytoplasm|",mitotic cell cycle|cell cycle|chromosome segregation|mitotic nuclear division|cell division|kinetochore assembly|,DNA binding|protein binding|centromeric DNA binding|,10,0.5,3.7,10,0.2,1.18,0.3,4.21,4.21,0.287,0,0,-0.4,1.3
ENSMUSG00000028334,NANS,N-acetylneuraminic acid synthase (sialic acid synthase),cytosol|extracellular vesicular exosome|,None,N-acylneuraminate-9-phosphate synthase activity|,10,0.4,1.56,10,0.4,2.86,0.4,4.17,4.17,0.29,0,0,-0.1,1.4
ENSMUSG00000093769,HIST2H3C1,"histone cluster 2, H3c1",nuclear chromosome|nucleus|nucleus|membrane|protein complex|extracellular vesicular exosome|,negative regulation of transcription from RNA polymerase II promoter|DNA replication-dependent nucleosome assembly|regulation of gene silencing|,chromatin binding|,10,-0.4,3.58,10,-0.3,0.836,-0.3,4.17,-4.17,0.29,0,0,-1.3,0.4
ENSMUSG00000027076,TIMM10,translocase of inner mitochondrial membrane 10,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|mitochondrial intermembrane space protein transporter complex|mitochondrial intermembrane space protein transporter complex|,transport|protein transport|protein import into mitochondrial inner membrane|protein import into mitochondrial inner membrane|chaperone-mediated protein transport|,transporter activity|protein homodimerization activity|metal ion binding|chaperone binding|,8,-0.5,3.93,8,0.9,5.48,-0.5,4.15,-4.15,0.291,0,0,-1.1,1.8
ENSMUSG00000009185,CCL8,chemokine (C-C motif) ligand 8,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|,cytokine activity|chemokine activity|heparin binding|,10,0.2,0.589,10,1.4,6.37,0.2,4.14,4.14,0.292,0,0,0.1,3
ENSMUSG00000026672,OPTN,optineurin,cytoplasm|Golgi apparatus|Golgi apparatus|trans-Golgi network|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|perinuclear region of cytoplasm|,protein targeting to Golgi|negative regulation of receptor recycling|Golgi organization|positive regulation of cell proliferation|macroautophagy|cellular protein localization|Golgi to plasma membrane protein transport|negative regulation of neuron apoptotic process|cytokine secretion|defense response to Gram-negative bacterium|protein homooligomerization|Golgi ribbon formation|,TFIIIA-class transcription factor binding|protein binding|protein C-terminus binding|polyubiquitin binding|identical protein binding|ubiquitin binding|,10,-0.5,3,10,-0.5,1.33,-0.5,4.09,-4.09,0.295,0,0,-1.6,0.4
ENSMUSG00000022305,LRP12,low density lipoprotein-related protein 12,integral component of plasma membrane|coated pit|membrane|integral component of membrane|,endocytosis|biological_process|,molecular_function|,10,0.4,1.81,10,0.5,2.63,0.5,4.07,4.07,0.296,0,0,-0.1,1.6
ENSMUSG00000033491,PRSS35,"protease, serine 35",extracellular region|mitochondrion|,proteolysis|,catalytic activity|serine-type endopeptidase activity|,10,0.3,1.55,10,0.8,4.74,0.7,4.06,4.06,0.297,0,0,0,1.8
ENSMUSG00000013611,SNX31,sorting nexin 31,protein complex|,transport|protein transport|,phosphatidylinositol binding|,10,0.4,1.77,10,0.6,2.66,0.5,4.02,4.02,0.3,0,0,-0.2,1.5
ENSMUSG00000036832,LPAR3,lysophosphatidic acid receptor 3,plasma membrane|membrane|integral component of membrane|axon|,activation of MAPK activity|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|bleb assembly|positive regulation of MAPK cascade|positive regulation of collateral sprouting|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|positive regulation of calcium ion transport|,G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|phospholipid binding|lysophosphatidic acid receptor activity|,10,0.2,1.27,10,0.5,3.52,0.4,4.01,4.01,0.3,0,0,-0.2,1.5
ENSMUSG00000008604,UBQLN4,ubiquilin 4,nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|centrosome|cytosol|nuclear proteasome complex|cytosolic proteasome complex|intracellular membrane-bounded organelle|,regulation of proteasomal ubiquitin-dependent protein catabolic process|,polyubiquitin binding|identical protein binding|,10,-0.4,1.35,10,-0.5,3.16,-0.4,4,-4,0.301,0,0,-1.5,0.1
ENSMUSG00000024270,SLC39A6,"solute carrier family 39 (metal ion transporter), member 6",endoplasmic reticulum|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|lamellipodium membrane|,transport|ion transport|zinc ion transport|cellular zinc ion homeostasis|metal ion transport|transmembrane transport|zinc ion transmembrane transport|zinc ion transmembrane import|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|metal ion transmembrane transporter activity|,10,0.4,3.78,10,0.2,0.661,0.3,4,4,0.301,0,0,-0.8,1.2
ENSMUSG00000019913,SIM1,single-minded homolog 1 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|multicellular organismal development|nervous system development|cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|protein binding|protein heterodimerization activity|protein dimerization activity|,10,0.4,2.53,10,0.3,1.96,0.4,4,4,0.301,0,0,-0.3,1.3
ENSMUSG00000021831,ERO1L,ERO1-like (S. cerevisiae),intracellular|cell|endoplasmic reticulum|membrane|membrane|integral component of endoplasmic reticulum membrane|,protein folding|protein folding|transport|apoptotic process|4-hydroxyproline metabolic process|protein maturation by protein folding|extracellular matrix organization|endoplasmic reticulum unfolded protein response|response to endoplasmic reticulum stress|cell redox homeostasis|brown fat cell differentiation|chaperone mediated protein folding requiring cofactor|release of sequestered calcium ion into cytosol|oxidation-reduction process|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,"protein disulfide isomerase activity|peptide-methionine (S)-S-oxide reductase activity|protein disulfide oxidoreductase activity|oxidoreductase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor|peptide-methionine (R)-S-oxide reductase activity|methionine-R-sulfoxide reductase activity|",10,0.2,0.38,10,-0.9,6.29,-0.6,3.99,-3.99,0.301,0,0,-1.9,0.1
ENSMUSG00000091609,ACER2,alkaline ceramidase 2,Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,negative regulation of cell-matrix adhesion|lipid metabolic process|ceramide metabolic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of cell proliferation|positive regulation of cell death|response to retinoic acid|negative regulation of cell adhesion mediated by integrin|sphingosine biosynthetic process|negative regulation of protein glycosylation in Golgi|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|ceramidase activity|dihydroceramidase activity|",6,-0.9,6.15,5,0.3,0.475,-0.9,3.98,-3.98,0.302,0,0,-2,0.7
ENSMUSG00000016239,LONRF3,LON peptidase N-terminal domain and ring finger 3,cellular_component|,proteolysis|biological_process|,molecular_function|ATP-dependent peptidase activity|zinc ion binding|metal ion binding|,10,-0.2,1.25,10,-0.3,3.16,-0.3,3.96,-3.96,0.303,0,0,-1.4,0.2
ENSMUSG00000035953,TMEM55B,transmembrane protein 55b,cellular_component|lysosome|endosome|membrane|integral component of membrane|,biological_process|,molecular_function|hydrolase activity|,10,0.4,4.18,10,0.2,0.843,0.3,3.96,3.96,0.303,0,0,-0.2,1.3
ENSMUSG00000038173,ENPP6,ectonucleotide pyrophosphatase/phosphodiesterase 6,extracellular region|plasma membrane|plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,lipid metabolic process|metabolic process|lipid catabolic process|choline metabolic process|choline metabolic process|,"catalytic activity|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|photoreceptor cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity|glycerophosphocholine cholinephosphodiesterase activity|inositol phosphosphingolipid phospholipase activity|inositol phosphorylceramide phospholipase activity|mannosyl-inositol phosphorylceramide phospholipase activity|mannosyl-diinositol phosphorylceramide phospholipase activity|",10,0.7,6.78,10,-0.7,0.501,0.7,3.95,3.95,0.304,0,0,-0.4,2
ENSMUSG00000051136,GHSR,growth hormone secretagogue receptor,cell|plasma membrane|cell surface|membrane|integral component of membrane|neuron projection|membrane raft|,signal transduction|G-protein coupled receptor signaling pathway|actin polymerization or depolymerization|adult feeding behavior|response to hormone|hormone-mediated signaling pathway|growth hormone secretion|response to food|positive regulation of appetite|negative regulation of interleukin-1 beta production|cellular response to insulin stimulus|positive regulation of multicellular organism growth|negative regulation of tumor necrosis factor biosynthetic process|regulation of hindgut contraction|positive regulation of insulin-like growth factor receptor signaling pathway|negative regulation of interleukin-6 biosynthetic process|positive regulation of fatty acid metabolic process|negative regulation of insulin secretion|decidualization|negative regulation of inflammatory response|regulation of synapse assembly|,growth hormone secretagogue receptor activity|signal transducer activity|G-protein coupled receptor activity|growth hormone-releasing hormone receptor activity|peptide hormone binding|hormone binding|,10,-0.5,5.1,10,-0.1,0.0721,-0.4,3.91,-3.91,0.307,0,0,-1.6,0.4
ENSMUSG00000044122,PROCA1,protein interacting with cyclin A1,cellular_component|,biological_process|,molecular_function|,10,0.6,2.68,10,0.6,1.47,0.6,3.91,3.91,0.307,0,0,-0.1,1.7
ENSMUSG00000049044,RAPGEF4,Rap guanine nucleotide exchange factor (GEF) 4,photoreceptor outer segment|photoreceptor inner segment|intracellular|cytoplasm|cytosol|plasma membrane|cAMP-dependent protein kinase complex|membrane|basolateral plasma membrane|apical plasma membrane|axon|dendrite|dendritic spine|protein complex|excitatory synapse|,regulation of protein phosphorylation|exocytosis|signal transduction|small GTPase mediated signal transduction|positive regulation of smooth muscle cell migration|calcium ion-dependent exocytosis|regulation of exocytosis|cAMP-mediated signaling|insulin secretion|positive regulation of Ras GTPase activity|intracellular signal transduction|positive regulation of GTPase activity|regulation of dendrite development|negative regulation of synaptic transmission|regulation of small GTPase mediated signal transduction|,nucleotide binding|guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|protein binding|cAMP-dependent protein kinase regulator activity|Ras GTPase binding|cAMP binding|cAMP binding|protein complex binding|,10,0.8,6.29,10,0,0,0.8,3.87,3.87,0.31,0,0,-0.1,1.9
ENSMUSG00000061778,MOSPD2,motile sperm domain containing 2,membrane|membrane|integral component of membrane|,biological_process|,molecular_function|structural molecule activity|,10,-0.9,3.8,10,-0.8,0.326,-0.9,3.87,-3.87,0.31,0,0,-2,0.5
ENSMUSG00000059406,TMPRSS9,"transmembrane protease, serine 9",membrane|integral component of membrane|,proteolysis|proteolysis|plasminogen activation|,peptidase activity|serine-type peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.4,1.02,10,0.4,3.07,0.4,3.86,3.86,0.31,0,0,-0.2,1.4
ENSMUSG00000032318,ISL2,insulin related protein 2 (islet 2),intracellular|nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|spinal cord motor neuron cell fate specification|visceral motor neuron differentiation|visceral motor neuron differentiation|retinal ganglion cell axon guidance|negative regulation of neuron differentiation|negative regulation of neuron differentiation|neuron fate commitment|neuron fate commitment|",DNA binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.2,1.51,10,-0.3,2.57,-0.3,3.75,-3.75,0.318,0,0,-1.1,0.6
ENSMUSG00000062202,BTBD9,BTB (POZ) domain containing 9,cellular_component|,"cell adhesion|long-term memory|adult locomotory behavior|serotonin metabolic process|circadian sleep/wake cycle, non-REM sleep|circadian behavior|sensory perception of temperature stimulus|multicellular organismal iron ion homeostasis|regulation of synaptic vesicle endocytosis|",molecular_function|,10,0.2,0.429,10,0.4,4.25,0.3,3.73,3.73,0.32,0,0,-0.3,1.3
ENSMUSG00000079258,CALHM1,calcium homeostasis modulator 1,endoplasmic reticulum|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|calcium ion transport|ATP transport|ion transmembrane transport|regulation of ion transmembrane transport|regulation of ion transmembrane transport|sensory perception of bitter taste|sensory perception of sweet taste|sensory perception of umami taste|protein homooligomerization|calcium ion transmembrane transport|,calcium activated cation channel activity|voltage-gated ion channel activity|voltage-gated ion channel activity|calcium channel activity|identical protein binding|,10,-0.5,4.75,10,0.3,1.26,0.4,3.73,3.73,0.32,0,0,-1.3,1.2
ENSMUSG00000032038,ST3GAL4,"ST3 beta-galactoside alpha-2,3-sialyltransferase 4",Golgi apparatus|membrane|membrane|integral component of membrane|integral component of Golgi membrane|extracellular vesicular exosome|,protein glycosylation|cognition|sialylation|sialylation|,"beta-galactoside (CMP) alpha-2,3-sialyltransferase activity|sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|monosialoganglioside sialyltransferase activity|",10,0.5,3.27,10,0.2,1.1,0.4,3.71,3.71,0.321,0,0,-0.2,1.5
ENSMUSG00000033909,USP36,ubiquitin specific peptidase 36,nucleus|nucleolus|,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|poly(A) RNA binding|,10,0.2,0.789,10,0.3,3.3,0.3,3.65,3.65,0.327,0,0,-1.2,1.2
ENSMUSG00000027435,CD93,CD93 antigen,plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|,cell adhesion|single organismal cell-cell adhesion|single organismal cell-cell adhesion|,complement component C1q binding|calcium ion binding|carbohydrate binding|,10,-0.3,1.64,10,-0.3,2.23,-0.3,3.63,-3.63,0.328,0,0,-1.4,0.9
ENSMUSG00000030244,GYS2,glycogen synthase 2,cytoplasm|cytosol|cytoskeleton|cell cortex|cortical actin cytoskeleton|ectoplasm|,glycogen metabolic process|glycogen biosynthetic process|metabolic process|response to glucose|,"catalytic activity|glycogen (starch) synthase activity|glucose binding|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.4,1.71,10,0.4,4.32,0.3,3.62,3.62,0.329,0,0,-0.8,1.4
ENSMUSG00000046324,ERMP1,endoplasmic reticulum metallopeptidase 1,endoplasmic reticulum|membrane|membrane|integral component of membrane|,ovarian follicle development|proteolysis|,molecular_function|peptidase activity|cysteine-type peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,-0.4,2.16,10,-0.4,1.67,-0.4,3.6,-3.6,0.331,0,0,-1.5,0.4
ENSMUSG00000061244,EXOC5,exocyst complex component 5,cytoplasm|cytosol|,transport|exocytosis|biological_process|protein transport|vesicle docking|,protein N-terminus binding|,10,1.3,3.72,10,0.4,3.74,1,3.6,3.6,0.331,0,0,0,2.5
ENSMUSG00000040471,GGT6,gamma-glutamyltransferase 6,membrane|integral component of membrane|extracellular vesicular exosome|,glutathione metabolic process|glutathione biosynthetic process|biological_process|,"molecular_function|gamma-glutamyltransferase activity|transferase activity|transferase activity, transferring acyl groups|hydrolase activity|glutathione hydrolase activity|",10,-0.3,1.51,10,0.3,3.11,0.3,3.59,3.59,0.331,0,0,-1,1.2
ENSMUSG00000025027,XPNPEP1,"X-prolyl aminopeptidase (aminopeptidase P) 1, soluble",cytoplasm|cytosol|extracellular vesicular exosome|,proteolysis|bradykinin catabolic process|,aminopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|manganese ion binding|protein homodimerization activity|metal ion binding|metalloaminopeptidase activity|,10,0.3,2.13,10,0.3,1.69,0.3,3.59,3.59,0.331,0,0,-0.5,1.2
ENSMUSG00000039154,SHD,src homology 2 domain-containing transforming protein D,cellular_component|,biological_process|,molecular_function|,10,0.2,1.04,10,0.4,3.35,0.3,3.58,3.58,0.332,0,0,-0.2,1.4
ENSMUSG00000026930,GPSM1,"G-protein signalling modulator 1 (AGS3-like, C. elegans)",cytoplasm|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|,multicellular organismal development|nervous system development|regulation of G-protein coupled receptor protein signaling pathway|cell differentiation|,G-protein alpha-subunit binding|GDP-dissociation inhibitor activity|protein binding|GTPase regulator activity|,10,-0.5,4.85,10,0.4,1.91,-0.4,3.56,-3.56,0.334,0,0,-1.6,0.8
ENSMUSG00000052566,HOOK2,hook homolog 2 (Drosophila),cytoplasm|centrosome|cytoskeleton|microtubule|HOPS complex|FHF complex|,transport|endosome organization|lysosome organization|endosome to lysosome transport|protein transport|early endosome to late endosome transport|,identical protein binding|,10,-0.2,1.82,10,0.5,3.31,-0.3,3.54,-3.54,0.336,0,0,-1.3,1.3
ENSMUSG00000027671,ACTL6A,actin-like 6A,nuclear chromatin|nucleus|nucleus|plasma membrane|SWI/SNF complex|Ino80 complex|NuA4 histone acetyltransferase complex|protein complex|npBAF complex|npBAF complex|,"DNA repair|DNA recombination|chromatin remodeling|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|nervous system development|chromatin modification|regulation of growth|ATP-dependent chromatin remodeling|histone H4 acetylation|histone H2A acetylation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|chromatin binding|protein binding|nucleosomal DNA binding|,9,0.3,1.72,9,0.4,2.28,0.3,3.5,3.5,0.339,0,0,-0.6,1.5
ENSMUSG00000026878,RAB14,"RAB14, member RAS oncogene family",intracellular|intracellular|cell|lysosome|lysosomal membrane|endosome|early endosome|late endosome|rough endoplasmic reticulum|Golgi apparatus|Golgi stack|cytosol|plasma membrane|membrane|apical plasma membrane|transport vesicle|trans-Golgi network transport vesicle|cytoplasmic vesicle|nuclear outer membrane-endoplasmic reticulum membrane network|intracellular membrane-bounded organelle|phagocytic vesicle|perinuclear region of cytoplasm|recycling endosome|extracellular vesicular exosome|alveolar lamellar body|,GTP catabolic process|transport|Golgi to endosome transport|small GTPase mediated signal transduction|body fluid secretion|fibroblast growth factor receptor signaling pathway|embryo development|protein transport|endocytic recycling|regulation of protein localization|apical protein localization|,nucleotide binding|glycoprotein binding|GTPase activity|protein binding|GTP binding|GDP binding|,10,0.3,1.52,10,0.4,2.26,0.4,3.5,3.5,0.339,0,0,-0.2,1.4
ENSMUSG00000024771,LIPK,"lipase, family member K",cellular_component|extracellular region|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|hydrolase activity, acting on ester bonds|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.4,1.33,10,0.3,2.52,0.4,3.5,3.5,0.339,0,0,-0.2,1.4
ENSMUSG00000032690,OAS2,2'-5' oligoadenylate synthetase 2,nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,immune system process|purine nucleotide biosynthetic process|RNA catabolic process|protein glycosylation|immune response|response to virus|protein myristoylation|innate immune response|defense response to virus|,nucleotide binding|2'-5'-oligoadenylate synthetase activity|2'-5'-oligoadenylate synthetase activity|RNA binding|double-stranded RNA binding|double-stranded RNA binding|ATP binding|zinc ion binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,0,0,10,-0.6,5.91,-0.6,3.46,-3.46,0.342,0,0,-1.7,0.3
ENSMUSG00000078451,PPIL6,peptidylprolyl isomerase (cyclophilin)-like 6,cellular_component|,protein peptidyl-prolyl isomerization|protein folding|biological_process|,molecular_function|peptidyl-prolyl cis-trans isomerase activity|isomerase activity|,10,-0.3,2.59,10,-0.2,1.13,-0.3,3.45,-3.45,0.343,0,0,-1.4,0.3
ENSMUSG00000051343,RAB11FIP5,RAB11 family interacting protein 5 (class I),cell|cytoplasm|mitochondrion|mitochondrial outer membrane|endosome|early endosome|Golgi apparatus|microtubule organizing center|membrane|secretory granule|cytoplasmic vesicle|intracellular membrane-bounded organelle|recycling endosome|,transport|protein transport|insulin secretion involved in cellular response to glucose stimulus|regulated secretory pathway|cellular response to acidity|regulation of protein localization to cell surface|,gamma-tubulin binding|,10,-0.4,4.61,10,0,0,-0.4,3.44,-3.44,0.343,0,0,-1.5,0.7
ENSMUSG00000005481,DDX39,DEAD (Asp-Glu-Ala-Asp) box polypeptide 39,nucleus|cytoplasm|membrane|,"mRNA splicing, via spliceosome|mRNA processing|mRNA export from nucleus|RNA splicing|",nucleotide binding|nucleic acid binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,0.3,2.82,10,1.1,2.45,0.4,3.42,3.42,0.345,0,0,0,1.8
ENSMUSG00000035765,DYM,dymeclin,cytoplasm|Golgi apparatus|,Golgi organization|bone development|,enzyme binding|,10,0.4,5.29,10,-0.2,0.724,0.4,3.42,3.42,0.345,0,0,-0.6,1.4
ENSMUSG00000027810,EIF2A,eukaryotic translation initiation factor 2A,extracellular space|cytoplasm|eukaryotic translation initiation factor 2 complex|blood microparticle|,translation|translation|translational initiation|regulation of translation|protein phosphorylation|positive regulation of signal transduction|SREBP signaling pathway|ribosome assembly|,tRNA binding|translation initiation factor activity|ribosome binding|,10,1,2.51,10,0.8,1.31,0.9,3.41,3.41,0.346,0,0,0,1.9
ENSMUSG00000020705,DDX42,DEAD (Asp-Glu-Ala-Asp) box polypeptide 42,nucleus|cytoplasm|membrane|,protein localization|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,0.8,6.03,10,-0.1,0.0774,0.5,3.41,3.41,0.346,0,0,-0.2,1.8
ENSMUSG00000023068,NUS1,nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae),intracellular|cell|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,angiogenesis|multicellular organismal development|cell differentiation|intracellular cholesterol transport|intracellular cholesterol transport|sterol homeostasis|,"molecular_function|transferase activity, transferring alkyl or aryl (other than methyl) groups|",10,-0.3,1.37,10,1,5.97,0.9,3.4,3.4,0.346,0,0,-0.9,2
ENSMUSG00000027111,ITGA6,integrin alpha 6,basement membrane|plasma membrane|plasma membrane|cell-cell adherens junction|integrin complex|external side of plasma membrane|basal plasma membrane|cell surface|cell surface|membrane|integral component of membrane|basolateral plasma membrane|hemidesmosome|filopodium|integrin alpha6-beta4 complex|basal part of cell|,cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|positive regulation of cell-substrate adhesion|single organismal cell-cell adhesion|positive regulation of cell-cell adhesion|cell-substrate adhesion|cellular response to extracellular stimulus|cell adhesion mediated by integrin|positive regulation of phosphorylation|odontogenesis of dentin-containing tooth|positive regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|filopodium assembly|brown fat cell differentiation|leukocyte migration|leukocyte migration|negative regulation of extrinsic apoptotic signaling pathway|,integrin binding|protein complex binding|laminin binding|metal ion binding|,10,0,0,10,-0.7,5.84,-0.7,3.4,-3.4,0.346,0,0,-1.8,0.2
ENSMUSG00000024594,PRRC1,proline-rich coiled-coil 1,cellular_component|Golgi apparatus|,biological_process|,identical protein binding|,10,0.1,0.253,10,0.5,4.36,0.4,3.39,3.39,0.347,0,0,-0.3,1.4
ENSMUSG00000035329,FBXO33,F-box protein 33,cellular_component|,biological_process|,molecular_function|,10,0.2,1.03,10,0.4,2.66,0.3,3.38,3.38,0.348,0,0,-0.5,1.3
ENSMUSG00000048520,FBXL13,F-box and leucine-rich repeat protein 13,cellular_component|,biological_process|,molecular_function|,10,-0.5,3.07,10,0.4,5.6,0.4,3.37,3.37,0.349,0,0,-1.1,1.5
ENSMUSG00000027465,TBC1D20,"TBC1 domain family, member 20",cellular_component|membrane|integral component of membrane|,acrosome assembly|lens development in camera-type eye|Golgi organization|spermatogenesis|male gonad development|regulation of Rab GTPase activity|lipid particle organization|camera-type eye development|lens fiber cell morphogenesis|seminiferous tubule development|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,0.3,2.51,10,0.5,1.26,0.4,3.37,3.37,0.349,0,0,-0.4,1.5
ENSMUSG00000020496,RNF187,ring finger protein 187,nucleus|cytoplasm|,"positive regulation of cell proliferation|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of transcription, DNA-templated|protein autoubiquitination|protein K48-linked ubiquitination|","ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.6,3.69,10,0.2,1.06,0.4,3.34,3.34,0.352,0,0,-0.6,1.6
ENSMUSG00000019948,ACTR6,ARP6 actin-related protein 6,cellular_component|nucleus|cytoplasm|cytoskeleton|,biological_process|,molecular_function|,9,-0.2,0.0832,9,0.7,5.32,0.6,3.33,3.33,0.353,0,0,-1.3,1.8
ENSMUSG00000060090,RP2H,retinitis pigmentosa 2 homolog (human),cytoplasm|Golgi apparatus|centriole|plasma membrane|plasma membrane|cilium|membrane|cytoplasmic vesicle|ciliary basal body|ciliary basal body|cell projection|extracellular vesicular exosome|periciliary membrane compartment|,cell morphogenesis|nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|transport|post-Golgi vesicle-mediated transport|cytoskeleton organization|protein transport|positive regulation of GTPase activity|,nucleotide binding|actin binding|nucleoside diphosphate kinase activity|GTPase activator activity|ATP binding|GTP binding|,10,0.2,1,10,0.9,3.78,0.4,3.3,3.3,0.355,0,0,-0.2,1.8
ENSMUSG00000018774,CD68,CD68 antigen,lysosome|endosome|plasma membrane|membrane|integral component of membrane|,cellular response to organic substance|,None,10,0.3,1.57,10,-0.4,1.99,0.5,3.28,3.28,0.357,0,0,-0.9,1.5
ENSMUSG00000032252,GLCE,glucuronyl C5-epimerase,Golgi apparatus|membrane|integral component of membrane|,glycosaminoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process|heparan sulfate proteoglycan biosynthetic process|heparin biosynthetic process|,"isomerase activity|racemase and epimerase activity, acting on carbohydrates and derivatives|racemase and epimerase activity, acting on carbohydrates and derivatives|heparosan-N-sulfate-glucuronate 5-epimerase activity|UDP-glucuronate 5'-epimerase activity|UDP-glucuronate 5'-epimerase activity|",10,0.4,4.43,10,0,0,0.4,3.28,3.28,0.357,0,0,-0.6,1.4
ENSMUSG00000035042,CCL5,chemokine (C-C motif) ligand 5,extracellular region|extracellular space|extracellular space|intracellular|cell|cytoplasm|,MAPK cascade|positive regulation of defense response to virus by host|protein phosphorylation|calcium ion transport|cellular calcium ion homeostasis|exocytosis|chemotaxis|inflammatory response|inflammatory response|immune response|leukocyte cell-cell adhesion|cell-cell signaling|response to toxic substance|positive regulation of gene expression|positive regulation of macrophage chemotaxis|positive regulation of T cell chemotaxis|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of smooth muscle cell migration|positive regulation of cell migration|pseudopodium assembly|positive regulation of cellular biosynthetic process|activation of phospholipase D activity|positive regulation of fever generation|lipopolysaccharide-mediated signaling pathway|positive regulation of cell-cell adhesion mediated by integrin|response to cytokine|positive regulation of homotypic cell-cell adhesion|response to interferon-gamma|response to tumor necrosis factor|T-helper 1 cell diapedesis|positive regulation of T cell proliferation|neutrophil activation|positive regulation of phosphorylation|positive regulation of tyrosine phosphorylation of STAT protein|protein kinase B signaling|cellular protein complex assembly|negative regulation by host of viral transcription|negative regulation of viral genome replication|positive regulation of neuron differentiation|positive regulation of osteoclast differentiation|negative regulation of G-protein coupled receptor protein signaling pathway|positive regulation of angiogenesis|positive regulation of cell adhesion|eosinophil chemotaxis|lymphocyte chemotaxis|positive regulation of smooth muscle cell proliferation|positive regulation of epithelial cell proliferation|regulation of T cell activation|positive chemotaxis|protein tetramerization|positive regulation of calcium ion transport|negative regulation of cell death|positive regulation of mast cell chemotaxis|positive regulation of protein tyrosine kinase activity|negative regulation of chemokine-mediated signaling pathway|negative regulation of T cell apoptotic process|positive regulation of T cell apoptotic process|cellular response to organic cyclic compound|positive regulation of monocyte chemotaxis|positive regulation of monocyte chemotaxis|extracellular negative regulation of signal transduction|negative regulation of neuron death|negative regulation of macrophage apoptotic process|negative regulation of receptor activity|positive regulation of chemokine (C-X-C motif) ligand 2 production|positive regulation of T cell migration|positive regulation of natural killer cell chemotaxis|,phosphatidylinositol phospholipase C activity|protein kinase activity|cytokine activity|chemokine activity|heparin binding|phospholipase activator activity|receptor signaling protein tyrosine kinase activator activity|CCR1 chemokine receptor binding|CCR1 chemokine receptor binding|CCR5 chemokine receptor binding|chemoattractant activity|chemokine receptor binding|protein homodimerization activity|protein self-association|chemokine receptor antagonist activity|,10,-0.2,1.4,10,-0.4,2.44,-0.2,3.27,-3.27,0.358,0,0,-1.3,0.6
ENSMUSG00000004319,CLCN3,chloride channel 3,intracellular|endosome|early endosome|late endosome|Golgi apparatus|plasma membrane|vesicle membrane|membrane|integral component of membrane|apical plasma membrane|cytoplasmic vesicle|,transport|ion transport|chloride transport|ion transmembrane transport|regulation of ion transmembrane transport|regulation of anion transport|transmembrane transport|chloride transmembrane transport|,nucleotide binding|ion channel activity|voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|ATP binding|antiporter activity|PDZ domain binding|adenyl nucleotide binding|protein heterodimerization activity|,10,0.1,0.27,10,0.7,4.86,0.6,3.26,3.26,0.359,0,0,-0.1,1.8
ENSMUSG00000027879,SEC22B,SEC22 vesicle trafficking protein homolog B (S. cerevisiae),Golgi membrane|intracellular|cell|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|integral component of membrane|,transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,syntaxin binding|,10,-0.4,2.63,10,0.4,1.76,-0.4,3.24,-3.24,0.36,0,0,-1.5,1.2
ENSMUSG00000027180,FBXO3,F-box protein 3,nucleus|cytoplasm|,proteolysis|protein ubiquitination|,None,10,-0.6,1.05,10,-0.4,2.46,-0.5,3.22,-3.22,0.362,0,0,-1.6,1.1
ENSMUSG00000022622,ACR,acrosin prepropeptide,acrosomal vesicle|acrosomal vesicle|nucleus|Golgi-associated vesicle|acrosomal matrix|protein complex|,proteolysis|activation of adenylate cyclase activity|single fertilization|binding of sperm to zona pellucida|acrosome reaction|acrosome reaction|penetration of zona pellucida|penetration of zona pellucida|response to steroid hormone|,catalytic activity|serine-type endopeptidase activity|serine-type endopeptidase activity|protein binding|mannose binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.3,1.21,10,0.3,2.2,0.3,3.2,3.2,0.364,0,0,-0.5,1.4
ENSMUSG00000023030,SLC11A2,"solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2",nucleus|cytoplasm|lysosome|lysosomal membrane|endosome|early endosome|early endosome|late endosome|vacuole|trans-Golgi network|plasma membrane|plasma membrane|integral component of plasma membrane|brush border|cell surface|cell surface|endomembrane system|membrane|membrane|integral component of membrane|apical plasma membrane|cytoplasmic vesicle|late endosome membrane|apical part of cell|basal part of cell|perinuclear region of cytoplasm|recycling endosome|recycling endosome|paraferritin complex|,transition metal ion transport|porphyrin-containing compound metabolic process|porphyrin-containing compound biosynthetic process|heme biosynthetic process|transport|ion transport|cobalt ion transport|cobalt ion transport|copper ion transport|iron ion transport|iron ion transport|manganese ion transport|cellular copper ion homeostasis|activation of cysteine-type endopeptidase activity involved in apoptotic process|learning or memory|response to manganese ion|nickel cation transport|vanadium ion transport|ferrous iron transport|ferrous iron transport|lead ion transport|proton transport|proton transport|cellular response to oxidative stress|nickel cation transmembrane transport|dendrite morphogenesis|erythrocyte development|iron ion homeostasis|multicellular organismal iron ion homeostasis|multicellular organismal iron ion homeostasis|cadmium ion transmembrane transport|ferrous iron import|ferrous iron import|ferrous iron import|manganese ion transmembrane transport|zinc ion transmembrane transport|hydrogen ion transmembrane transport|copper ion import into cell|,transporter activity|copper ion transmembrane transporter activity|iron ion transmembrane transporter activity|iron ion transmembrane transporter activity|manganese ion transmembrane transporter activity|iron ion binding|copper ion binding|zinc ion binding|hydrogen ion transmembrane transporter activity|cadmium ion transmembrane transporter activity|cobalt ion transmembrane transporter activity|cobalt ion transmembrane transporter activity|ferrous iron transmembrane transporter activity|ferrous iron transmembrane transporter activity|lead ion transmembrane transporter activity|nickel cation transmembrane transporter activity|vanadium ion transmembrane transporter activity|solute:proton symporter activity|nickel cation binding|inorganic cation transmembrane transporter activity|manganese ion binding|cadmium ion binding|cobalt ion binding|,10,0,0,10,-1.2,6.22,-1.2,3.16,-3.16,0.367,0,0,-2,-0.1
ENSMUSG00000029610,AIMP2,aminoacyl tRNA synthetase complex-interacting multifunctional protein 2,nucleus|cytoplasm|membrane|,translation|apoptotic process|multicellular organismal development|negative regulation of cell proliferation|cell differentiation|positive regulation of protein ubiquitination|Type II pneumocyte differentiation|positive regulation of neuron death|,protein binding|,10,-0.8,4.7,10,0.4,3.25,-0.7,3.14,-3.14,0.369,0,0,-1.8,0.8
ENSMUSG00000019578,UBXN6,UBX domain protein 6,nucleus|cytoplasm|cytoskeleton|extracellular vesicular exosome|,None,None,10,1.3,2.49,10,0.3,1.65,0.2,3.13,3.13,0.37,0,0,-0.2,2
ENSMUSG00000034532,FBXO16,F-box protein 16,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.68,10,0.4,3.53,0.3,3.09,3.09,0.374,0,0,-0.6,2.6
ENSMUSG00000029657,HSPH1,heat shock 105kDa/110kDa protein 1,extracellular region|nucleus|cytoplasm|cytosol|microtubule|extracellular vesicular exosome|,response to stress|response to unfolded protein|negative regulation of neuron apoptotic process|positive regulation of MHC class I biosynthetic process|chaperone mediated protein folding requiring cofactor|positive regulation of NK T cell activation|regulation of microtubule cytoskeleton organization|,nucleotide binding|protein binding|ATP binding|alpha-tubulin binding|,10,-0.4,4.36,10,0.9,1.12,-0.3,3.08,-3.08,0.375,0,0,-1.1,1.7
ENSMUSG00000058318,PHF21A,PHD finger protein 21A,histone deacetylase complex|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|suckling behavior|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|",DNA binding|chromatin binding|zinc ion binding|metal ion binding|,10,0.8,3.86,10,-0.2,1.18,0.7,3.05,3.05,0.377,0,0,-0.6,1.9
ENSMUSG00000029569,TMEM168,transmembrane protein 168,membrane|integral component of membrane|transport vesicle|,biological_process|,molecular_function|,10,0.5,2.19,10,0.3,1.26,0.3,3.04,3.04,0.378,0,0,-0.3,1.5
ENSMUSG00000002871,TPRA1,"transmembrane protein, adipocyte asscociated 1",membrane|integral component of membrane|,None,None,10,0.3,0.651,10,0.3,2.57,0.3,3.03,3.03,0.379,0,0,-0.4,1.3
ENSMUSG00000004451,RALB,v-ral simian leukemia viral oncogene homolog B (ras related),plasma membrane|membrane|midbody|extracellular vesicular exosome|,cytokinesis|regulation of exocyst assembly|GTP catabolic process|apoptotic process|cell cycle|signal transduction|small GTPase mediated signal transduction|Ras protein signal transduction|cell division|regulation of exocyst localization|,nucleotide binding|GTPase activity|GTP binding|,10,0.2,0.453,10,0.7,3.48,0.6,3.03,3.03,0.379,0,0,-0.2,1.8
ENSMUSG00000031979,COG2,component of oligomeric golgi complex 2,Golgi apparatus|Golgi stack|cytosol|membrane|Golgi transport complex|,transport|intra-Golgi vesicle-mediated transport|Golgi organization|protein transport|,protein transporter activity|protein complex binding|,10,0.5,1.52,10,0.4,1.73,0.4,3.01,3.01,0.381,0,0,-1.3,1.5
ENSMUSG00000027244,ATG13,autophagy related 13,pre-autophagosomal structure|cytoplasm|cytosol|Atg1p signaling complex|ULK1-ATG13-FIP200 complex|ULK1-ATG13-FIP200 complex|,autophagic vacuole assembly|autophagic vacuole assembly|autophagy|,protein binding|protein kinase binding|protein kinase binding|,10,-0.7,0.395,10,0.9,4.61,0.7,3,3,0.382,0,0,-0.8,1.9
ENSMUSG00000002015,BCAP31,B cell receptor associated protein 31,Golgi membrane|intracellular|cell|mitochondrion|endoplasmic reticulum|endoplasmic reticulum membrane|lipid particle|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|clathrin-coated vesicle|Golgi cisterna membrane|,transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|ER to Golgi vesicle-mediated transport|apoptotic process|immune response|positive regulation of cytosolic calcium ion concentration|protein transport|vesicle-mediated transport|negative regulation of endoplasmic reticulum calcium ion concentration|calcium-mediated signaling using intracellular calcium source|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of mitochondrial calcium ion concentration|protein localization to endoplasmic reticulum exit site|positive regulation of intrinsic apoptotic signaling pathway|,protein binding|protein complex binding|MHC class I protein binding|,10,1.1,1.42,10,0.8,1.98,1,3,3,0.382,0,0,-0.3,2
ENSMUSG00000074652,MYH7B,"myosin, heavy chain 7B, cardiac muscle, beta",membrane|myosin complex|myosin filament|,None,nucleotide binding|motor activity|actin binding|ATP binding|,10,0.4,3.61,10,0.2,0.205,0.3,3,3,0.382,0,0,-0.4,1.5
ENSMUSG00000056071,S100A9,S100 calcium binding protein A9 (calgranulin B),extracellular region|extracellular space|nucleus|cytoplasm|cytoskeleton|plasma membrane|membrane|extracellular vesicular exosome|,immune system process|leukocyte migration involved in inflammatory response|autophagy|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|chemotaxis|inflammatory response|neutrophil chemotaxis|leukocyte chemotaxis|actin cytoskeleton reorganization|innate immune response|regulation of integrin biosynthetic process|regulation of inflammatory response|positive regulation of inflammatory response|neutrophil aggregation|positive regulation of intrinsic apoptotic signaling pathway|,calcium ion binding|microtubule binding|zinc ion binding|antioxidant activity|Toll-like receptor 4 binding|metal ion binding|arachidonic acid binding|RAGE receptor binding|,10,-0.4,2.06,10,-0.3,1.17,-0.3,2.99,-2.99,0.383,0,0,-1.4,0.7
ENSMUSG00000025198,ERLIN1,ER lipid raft associated 1,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|protein complex|,ER-associated ubiquitin-dependent protein catabolic process|,None,10,0.5,2.15,10,0.5,1.03,0.5,2.98,2.98,0.383,0,0,-0.2,1.7
ENSMUSG00000059796,EIF4A1,eukaryotic translation initiation factor 4A1,membrane|extracellular vesicular exosome|,translation|translational initiation|,nucleotide binding|nucleic acid binding|RNA binding|double-stranded RNA binding|translation initiation factor activity|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,9,-0.8,3.89,6,1.4,5.43,1.4,2.98,2.98,0.383,0,0,-1.3,3
ENSMUSG00000024687,OSBP,oxysterol binding protein,nucleus|cytoplasm|Golgi apparatus|membrane|cell junction|,transport|lipid transport|,lipid binding|,10,-0.8,0.53,10,-0.4,3.49,-0.6,2.97,-2.97,0.384,0,0,-1.7,1.3
ENSMUSG00000016946,KCTD5,potassium channel tetramerisation domain containing 5,cytoplasm|cytosol|,biological_process|protein homooligomerization|,protein complex binding|,10,0.3,1.69,10,0.2,1.6,0.2,2.95,2.95,0.387,0,0,-1.2,1.1
ENSMUSG00000038204,ASB10,ankyrin repeat and SOCS box-containing 10,nucleus|cytoplasm|,biological_process|intracellular signal transduction|,molecular_function|,10,0.6,2.2,10,0.5,1.08,0.6,2.95,2.95,0.387,0,0,-0.4,1.8
ENSMUSG00000050192,EIF5A2,eukaryotic translation initiation factor 5A2,nucleus|nuclear pore|cytoplasm|endoplasmic reticulum|membrane|,translation|translational elongation|translational frameshifting|transport|positive regulation of cell proliferation|peptidyl-lysine modification to peptidyl-hypusine|protein transport|positive regulation of translational elongation|positive regulation of translational termination|mRNA transport|,RNA binding|translation elongation factor activity|ribosome binding|,10,-0.4,3.07,10,-0.2,0.584,-0.3,2.92,-2.92,0.389,0,0,-1.6,0.5
ENSMUSG00000021135,SLC10A1,"solute carrier family 10 (sodium/bile acid cotransporter family), member 1",membrane|integral component of membrane|basolateral plasma membrane|,transport|ion transport|sodium ion transport|lipid transport|organic anion transport|bile acid and bile salt transport|sodium ion transmembrane transport|,bile acid:sodium symporter activity|bile acid transmembrane transporter activity|symporter activity|,10,-0.2,0.765,10,0.5,4.14,0.4,2.91,2.91,0.39,0,0,-0.7,1.6
ENSMUSG00000041697,COX6A1,cytochrome c oxidase subunit VIa polypeptide 1,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex IV|membrane|,None,cytochrome-c oxidase activity|,10,-0.2,0.556,10,-0.3,2.79,-0.2,2.9,-2.9,0.391,0,0,-1.5,0.6
ENSMUSG00000023391,DLX2,distal-less homeobox 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|proximal/distal pattern formation|proximal/distal pattern formation|subpallium development|hippocampus development|olfactory bulb development|forebrain neuron differentiation|regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment|cerebral cortex GABAergic interneuron differentiation|cerebral cortex GABAergic interneuron fate commitment|cell differentiation|odontogenesis of dentin-containing tooth|negative regulation of Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|embryonic cranial skeleton morphogenesis|embryonic skeletal system development|embryonic skeletal system development|negative regulation of oligodendrocyte differentiation|branching morphogenesis of a nerve|cartilage development|",DNA binding|chromatin binding|single-stranded RNA binding|protein binding|sequence-specific DNA binding|,10,-0.4,3.1,10,-0.1,0.44,-0.3,2.89,-2.89,0.392,0,0,-1.5,0.3
ENSMUSG00000031753,COG4,component of oligomeric golgi complex 4,Golgi apparatus|membrane|Golgi transport complex|,"transport|retrograde vesicle-mediated transport, Golgi to ER|Golgi organization|protein transport|Golgi vesicle prefusion complex stabilization|",molecular_function|,10,0.3,0.681,9,0.3,2.38,0.3,2.87,2.87,0.394,0,0,-0.8,1.5
ENSMUSG00000022247,BRIX1,"BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)",nucleus|nucleolus|,biological_process|ribosome biogenesis|,poly(A) RNA binding|,9,0.8,4.69,8,0.1,0.156,0.7,2.81,2.81,0.4,0,0,-0.4,2
ENSMUSG00000032114,SLC37A4,"solute carrier family 37 (glucose-6-phosphate transporter), member 4",membrane|integral component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,neutrophil homeostasis|cytokine production|myeloid progenitor cell differentiation|glycogen metabolic process|lactate metabolic process|triglyceride metabolic process|cellular calcium ion homeostasis|steroid metabolic process|response to organic cyclic compound|organic anion transport|glucose-6-phosphate transport|glucose-6-phosphate transport|glucose-6-phosphate transport|glucose-6-phosphate transport|neutrophil chemotaxis|negative regulation of chemokine production|ion transmembrane transport|post-embryonic hemopoiesis|glucose homeostasis|glucose homeostasis|cholesterol homeostasis|positive regulation of catalytic activity|respiratory burst|,glucose-6-phosphate transmembrane transporter activity|,10,-0.2,0.423,10,1.4,6.12,1.4,2.81,2.81,0.4,0,0,-0.2,3
ENSMUSG00000049904,TMEM17,transmembrane protein 17,plasma membrane|cilium|membrane|integral component of membrane|ciliary transition zone|TCTN-B9D complex|cell projection|ciliary membrane|,smoothened signaling pathway|cell projection organization|cilium assembly|,protein binding|,10,0.3,3.5,10,0.1,0.0577,0.3,2.8,2.8,0.401,0,0,-0.4,1.5
ENSMUSG00000072423,PSMB11,"proteasome (prosome, macropain) subunit, beta type, 11",proteasome complex|nucleus|cytoplasm|proteasome core complex|,proteolysis|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,-0.4,1.52,10,1.5,6.21,1.5,2.8,2.8,0.401,0,0,-0.5,3
ENSMUSG00000032458,COPB2,"coatomer protein complex, subunit beta 2 (beta prime)",Golgi membrane|cytoplasm|Golgi apparatus|Golgi apparatus|membrane|membrane coat|COPI vesicle coat|cytoplasmic vesicle|,transport|intracellular protein transport|intra-Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,protein kinase C binding|structural molecule activity|,8,-0.5,1.56,8,0.3,2.53,0.3,2.77,2.77,0.404,0,0,-1.3,1.5
ENSMUSG00000032757,BET1,blocked early in transport 1 homolog (S. cerevisiae),Golgi membrane|endoplasmic reticulum|Golgi apparatus|cis-Golgi network|membrane|membrane|integral component of membrane|SNARE complex|Golgi cisterna|,transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|vesicle fusion with Golgi apparatus|,syntaxin binding|,8,-0.3,1.04,8,0.5,2.81,0.4,2.76,2.76,0.405,0,0,-1,1.7
ENSMUSG00000058626,CAPN11,calpain 11,acrosomal vesicle|intracellular|cytoplasmic vesicle|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|,10,0.4,3.79,10,0,0,0.4,2.76,2.76,0.405,0,0,-0.3,1.5
ENSMUSG00000024487,YIPF5,"Yip1 domain family, member 5",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|ER to Golgi transport vesicle|cytoplasmic vesicle|nuclear outer membrane-endoplasmic reticulum membrane network|endoplasmic reticulum exit site|,transport|protein transport|vesicle-mediated transport|regulation of ER to Golgi vesicle-mediated transport|,molecular_function|,10,0.4,3.57,10,0.1,0.0598,0.3,2.73,2.73,0.409,0,0,-0.4,1.5
ENSMUSG00000025484,BET1L,blocked early in transport 1 homolog (S. cerevisiae)-like,Golgi membrane|Golgi membrane|endosome|Golgi apparatus|Golgi stack|membrane|membrane|integral component of membrane|integral component of Golgi membrane|,"transport|protein transport|retrograde transport, endosome to Golgi|",SNAP receptor activity|SNAP receptor activity|,10,0,0,10,0.3,3.43,0.2,2.73,2.73,0.409,0,0,-0.5,1.4
ENSMUSG00000025878,UIMC1,ubiquitin interaction motif containing 1,nucleus|nucleus|BRCA1-A complex|,"DNA repair|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|response to ionizing radiation|chromatin modification|G2 DNA damage checkpoint|positive regulation of DNA repair|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|histone H2A K63-linked deubiquitination|",histone binding|retinoid X receptor binding|K63-linked polyubiquitin binding|,10,0,0,10,0.8,5.47,0.7,2.72,2.72,0.41,0,0,-0.8,2
ENSMUSG00000024758,RTN3,reticulon 3,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,transport|apoptotic process|vesicle-mediated transport|endoplasmic reticulum tubular network organization|,protein binding|,10,-0.3,1.51,10,0.4,2.03,0.5,2.71,2.71,0.411,0,0,-0.7,1.7
ENSMUSG00000068855,HIST2H2AC,"histone cluster 2, H2ac",nucleosome|nucleus|chromosome|extracellular vesicular exosome|,None,DNA binding|protein heterodimerization activity|,9,0.9,2.87,9,0.2,1.13,0.3,2.7,2.7,0.412,0,0,-0.2,1.8
ENSMUSG00000042807,HECW2,"HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2",nucleus|cytoplasm|,protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.4,3.27,10,-0.1,0.0015,-0.3,2.69,-2.69,0.413,0,0,-1.4,1.2
ENSMUSG00000022120,RNF219,ring finger protein 219,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.5,3.65,10,0.1,0.288,0.3,2.69,2.69,0.413,0,0,-0.6,1.6
ENSMUSG00000024083,PJA2,"praja 2, RING-H2 motif containing",cytoplasm|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|cell junction|synapse|postsynaptic membrane|,long-term memory|regulation of protein kinase A signaling|protein ubiquitination|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein kinase A catalytic subunit binding|protein kinase A regulatory subunit binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,2.16,10,-0.2,0.696,-0.2,2.68,-2.68,0.414,0,0,-1.2,1.1
ENSMUSG00000073639,RAB18,"RAB18, member RAS oncogene family",intracellular|plasma membrane|membrane|extracellular vesicular exosome|,transport|small GTPase mediated signal transduction|multicellular organismal development|protein transport|lipid particle organization|,nucleotide binding|GTP binding|GDP binding|,10,0.1,0.0424,10,0.4,4.41,0.4,2.68,2.68,0.414,0,0,-0.5,1.8
ENSMUSG00000045954,SDPR,serum deprivation response,cytoplasm|cytosol|membrane|,positive regulation of transcription from RNA polymerase II promoter|,phosphatidylserine binding|lipid binding|,10,-0.3,1.89,10,-0.3,0.961,-0.3,2.66,-2.66,0.416,0,0,-1.5,0.4
ENSMUSG00000027582,ZGPAT,"zinc finger, CCCH-type with G patch domain",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of epidermal growth factor-activated receptor activity|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|metal ion binding|,10,-0.4,3.39,10,0.4,1.96,0.4,2.65,2.65,0.417,0,0,-1.1,1.3
ENSMUSG00000026177,SLC11A1,"solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1",lysosome|late endosome|late endosome|vacuole|plasma membrane|cell outer membrane|endosome membrane|membrane|integral component of membrane|phagocytic vesicle membrane|phagocytic vesicle membrane|phagocytic vesicle membrane|tertiary granule membrane|,"protein import into nucleus, translocation|MAPK cascade|negative regulation of cytokine production|positive regulation of cytokine production|T cell proliferation involved in immune response|T cell cytokine production|positive regulation of dendritic cell antigen processing and presentation|positive regulation of T-helper 1 type immune response|transport|ion transport|iron ion transport|iron ion transport|manganese ion transport|cellular cadmium ion homeostasis|cellular iron ion homeostasis|cellular iron ion homeostasis|phagocytosis|inflammatory response|vacuolar acidification|response to bacterium|response to bacterium|positive regulation of gene expression|nitrite transport|activation of protein kinase activity|response to lipopolysaccharide|response to lipopolysaccharide|response to lipopolysaccharide|interleukin-2 production|interleukin-3 production|positive regulation of interferon-gamma production|response to interferon-gamma|wound healing|macrophage activation|macrophage activation|defense response to bacterium|defense response to protozoan|L-arginine import|MHC class II biosynthetic process|respiratory burst|positive regulation of transcription from RNA polymerase II promoter|antigen processing and presentation of peptide antigen|mRNA stabilization|positive regulation of phagocytosis|defense response to Gram-negative bacterium|iron ion homeostasis|multicellular organismal iron ion homeostasis|cadmium ion transmembrane transport|divalent metal ion export|manganese ion transmembrane transport|hydrogen ion transmembrane transport|",transporter activity|manganese ion transmembrane transporter activity|protein homodimerization activity|transition metal ion transmembrane transporter activity|metal ion:proton antiporter activity|,10,0.4,4.13,10,0,0,0.3,2.64,2.64,0.419,0,0,-0.8,1.4
ENSMUSG00000030560,CTSC,cathepsin C,extracellular space|lysosome|endoplasmic reticulum|Golgi apparatus|membrane|extracellular vesicular exosome|,T cell mediated cytotoxicity|proteolysis|proteolysis|apoptotic process|response to organic substance|positive regulation of peptidase activity|positive regulation of proteolysis involved in cellular protein catabolic process|positive regulation of apoptotic signaling pathway|,serine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|peptidase activator activity involved in apoptotic process|hydrolase activity|phosphatase binding|chloride ion binding|identical protein binding|protein self-association|chaperone binding|,10,-0.2,1.15,10,-0.3,1.72,-0.2,2.64,-2.64,0.419,0,0,-1.2,1.4
ENSMUSG00000028035,DNAJB4,"DnaJ (Hsp40) homolog, subfamily B, member 4",nucleus|cytoplasm|cytosol|plasma membrane|extracellular vesicular exosome|,protein folding|,unfolded protein binding|chaperone binding|,10,-0.5,0.524,9,-0.6,2.37,-0.6,2.64,-2.64,0.419,0,0,-1.8,0.5
ENSMUSG00000029598,PLBD2,phospholipase B domain containing 2,lysosome|extracellular vesicular exosome|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.3,1.89,10,0.2,1.21,0.3,2.63,2.63,0.42,0,0,-0.5,1.5
ENSMUSG00000027366,SPPL2A,signal peptide peptidase like 2A,lysosome|lysosomal membrane|lysosomal membrane|endosome|plasma membrane|membrane|integral component of membrane|Golgi-associated vesicle membrane|late endosome membrane|integral component of cytoplasmic side of endoplasmic reticulum membrane|integral component of lumenal side of endoplasmic reticulum membrane|,proteolysis|membrane protein ectodomain proteolysis|membrane protein intracellular domain proteolysis|regulation of immune response|,"aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|protein homodimerization activity|",10,0.5,3.6,10,0.1,0.0159,0.4,2.61,2.61,0.422,0,0,-0.4,1.7
ENSMUSG00000024479,MAL2,"mal, T cell differentiation protein 2",plasma membrane|membrane|integral component of membrane|membrane raft|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.2,0.808,10,0.4,2.65,0.3,2.6,2.6,0.423,0,0,-0.4,1.6
ENSMUSG00000056899,IMMP2L,IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae),mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial inner membrane peptidase complex|,ovarian follicle development|proteolysis|protein processing involved in protein targeting to mitochondrion|spermatogenesis|protein localization|ovulation|,peptidase activity|peptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.4,1.93,10,-0.2,0.974,-0.3,2.6,-2.6,0.423,0,0,-1.6,0.3
ENSMUSG00000035638,MUC20,mucin 20,extracellular region|plasma membrane|basal plasma membrane|membrane|cell projection|,activation of MAPK activity|hepatocyte growth factor receptor signaling pathway|protein homooligomerization|,protein binding|,10,0.5,1.49,10,0.3,1.53,0.4,2.58,2.58,0.425,0,0,-0.5,1.6
ENSMUSG00000008429,HERPUD2,HERPUD family member 2,cellular_component|membrane|integral component of membrane|,response to unfolded protein|biological_process|,molecular_function|,9,0.4,3.86,9,-0.2,0.857,0.4,2.56,2.56,0.427,0,0,-0.9,1.5
ENSMUSG00000037415,RANBP10,RAN binding protein 10,nucleus|cytoplasm|cytoplasmic microtubule|,microtubule cytoskeleton organization|positive regulation of Ran GTPase activity|,Ran guanyl-nucleotide exchange factor activity|Ran GTPase binding|beta-tubulin binding|,10,-0.1,0.547,10,-1.3,5.33,-0.2,2.56,-2.56,0.427,0,0,-2,0
ENSMUSG00000028750,PLA2G2C,"phospholipase A2, group IIC",cellular_component|extracellular region|,lipid metabolic process|phospholipid metabolic process|phospholipid catabolic process|lipid catabolic process|,phospholipase A2 activity|calcium ion binding|hydrolase activity|metal ion binding|calcium-dependent phospholipase A2 activity|,10,-1.1,4.98,9,-0.1,0.00979,-0.2,2.55,-2.55,0.428,0,0,-2,0.4
ENSMUSG00000040726,HESX1,homeobox gene expressed in ES cells,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|brain development|otic vesicle formation|nose development|negative regulation of transcription, DNA-templated|forebrain morphogenesis|",DNA binding|chromatin binding|protein binding|protein C-terminus binding|transcription factor binding|sequence-specific DNA binding|protein N-terminus binding|,10,0.3,2.09,10,0.2,0.924,0.3,2.55,2.55,0.428,0,0,-0.6,1.4
ENSMUSG00000026280,ATG4B,"autophagy related 4B, cysteine peptidase",cytoplasm|cytoplasm|,autophagic vacuole assembly|proteolysis|proteolysis|transport|autophagy|autophagy|positive regulation of autophagy|protein transport|positive regulation of protein catabolic process|,endopeptidase activity|cysteine-type endopeptidase activity|protein binding|peptidase activity|cysteine-type peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.2,0.378,10,0.3,2.36,0.3,2.54,2.54,0.43,0,0,-0.6,1.5
ENSMUSG00000040022,RAB11FIP2,RAB11 family interacting protein 2 (class I),cell|nucleus|endosome|plasma membrane|membrane|intracellular membrane-bounded organelle|,transport|protein transport|establishment of cell polarity|insulin secretion involved in cellular response to glucose stimulus|regulated secretory pathway|,protein kinase binding|protein homodimerization activity|,10,0.8,2.52,10,0.4,1.14,0.7,2.53,2.53,0.431,0,0,-0.3,1.8
ENSMUSG00000041773,ENC1,ectodermal-neural cortex 1,nuclear chromatin|nucleus|nucleoplasm|nucleolus|cytoplasm|cytoskeleton|nuclear matrix|Cul3-RING ubiquitin ligase complex|neuronal cell body|,multicellular organismal development|proteasomal ubiquitin-independent protein catabolic process|positive regulation of neuron projection development|protein ubiquitination|negative regulation of translation|,actin binding|,10,-0.5,4.58,10,0.8,1.23,-0.4,2.53,-2.53,0.431,0,0,-1.6,1.4
ENSMUSG00000068323,SLC4A5,"solute carrier family 4, sodium bicarbonate cotransporter, member 5",cellular_component|,epithelial cell development|renal system process|regulation of systemic arterial blood pressure|ion transport|regulation of gene expression|cerebrospinal fluid secretion|mitochondrion distribution|retina development in camera-type eye|,molecular_function|,10,-0.4,4.82,10,0.4,3.59,-0.3,2.53,-2.53,0.431,0,0,-1.3,1.2
ENSMUSG00000024165,HN1L,hematological and neurological expressed 1-like,nucleus|cytoplasm|plasma membrane|,None,None,10,0.8,2.65,10,-0.3,2.92,-0.3,2.52,-2.52,0.432,0,0,-1.3,1.7
ENSMUSG00000019970,SGK1,serum/glucocorticoid regulated kinase 1,nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|plasma membrane|membrane|neuron projection|perinuclear region of cytoplasm|,protein phosphorylation|cellular sodium ion homeostasis|apoptotic process|response to stress|cellular response to DNA damage stimulus|microtubule depolymerization|long-term memory|visual learning|positive regulation of sodium ion transport|phosphorylation|peptidyl-serine phosphorylation|positive regulation of cell growth|negative regulation of microtubule polymerization|cellular response to insulin stimulus|regulation of protein localization|negative regulation of apoptotic process|glucocorticoid mediated signaling pathway|neuron projection morphogenesis|positive regulation of dendrite morphogenesis|regulation of cell cycle|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|3-phosphoinositide-dependent protein kinase binding|cofactor binding|tau protein binding|",10,-0.2,1.33,10,-0.6,2.59,-0.3,2.51,-2.51,0.433,0,0,-1.7,0.7
ENSMUSG00000023206,IL15RA,"interleukin 15 receptor, alpha chain",extracellular region|intracellular|nucleus|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,JAK-STAT cascade|negative regulation of neuron projection development|positive regulation of natural killer cell differentiation|,None,10,-0.3,0.797,10,-0.9,3.04,-0.5,2.5,-2.5,0.434,0,0,-1.9,0.3
ENSMUSG00000054409,TMEM74,transmembrane protein 74,cellular_component|lysosome|membrane|integral component of membrane|cytoplasmic vesicle|,autophagy|biological_process|,molecular_function|,10,-0.9,4.1,9,-0.2,0.608,0.3,2.48,2.48,0.436,0,0,-1.9,0.9
ENSMUSG00000032479,MAP4,microtubule-associated protein 4,cell|cytoplasm|cytoskeleton|microtubule|plasma membrane|microtubule cytoskeleton|extracellular vesicular exosome|mitotic spindle|,mitotic spindle organization|mitotic spindle organization|microtubule sliding|microtubule sliding|establishment of spindle orientation|establishment of spindle orientation|cell division|,microtubule binding|tubulin binding|poly(A) RNA binding|,10,0.5,1.81,10,-0.7,4.32,-0.4,2.48,-2.48,0.436,0,0,-1.6,1.3
ENSMUSG00000046490,RNF222,ring finger protein 222,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,9,-0.8,4.66,9,-0.1,0.405,-0.8,2.46,-2.46,0.439,0,0,-2,0.1
ENSMUSG00000021492,F12,coagulation factor XII (Hageman factor),extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|,plasma kallikrein-kinin cascade|Factor XII activation|proteolysis|blood coagulation|blood coagulation|hemostasis|positive regulation of plasminogen activation|protein processing|protein autoprocessing|regulation of blood coagulation|positive regulation of blood coagulation|zymogen activation|fibrinolysis|response to misfolded protein|positive regulation of fibrinolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|serine-type aminopeptidase activity|,10,0.4,2.5,10,-0.1,0.322,0.4,2.44,2.44,0.441,0,0,-0.5,1.6
ENSMUSG00000000392,FAP,fibroblast activation protein,extracellular space|plasma membrane|membrane|integral component of membrane|lamellipodium|cell junction|cell projection|apical part of cell|basal part of cell|,proteolysis|negative regulation of extracellular matrix disassembly|endothelial cell migration|,protease binding|endopeptidase activity|serine-type endopeptidase activity|peptidase activity|peptidase activity|serine-type peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.7,0.256,10,1,2.56,0.9,2.43,2.43,0.442,0,0,-0.1,2
ENSMUSG00000026977,7-Mar,membrane-associated ring finger (C3HC4) 7,cellular_component|,biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.7,1.04,10,0.3,2.43,0.4,2.42,2.42,0.444,0,0,-0.2,1.8
ENSMUSG00000046192,IQUB,IQ motif and ubiquitin domain containing,acrosomal vesicle|motile cilium|,smoothened signaling pathway|cell projection organization|cilium morphogenesis|,protein binding|,10,0.1,0.0461,10,0.7,4.73,0.6,2.42,2.42,0.444,0,0,-0.2,1.9
ENSMUSG00000046169,ADAMTS6,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6",cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.9,3.6,10,0.2,1.22,0.3,2.38,2.38,0.448,0,0,-0.1,1.9
ENSMUSG00000038506,DCUN1D2,"DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)",cellular_component|,biological_process|,molecular_function|,10,-0.3,3.03,10,0.2,0.881,-0.3,2.38,-2.38,0.448,0,0,-1.7,0.8
ENSMUSG00000028960,UBE4B,ubiquitination factor E4B,nucleus|,protein polyubiquitination|protein polyubiquitination|ventricular trabecula myocardium morphogenesis|ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|protein monoubiquitination|granzyme-mediated apoptotic signaling pathway|response to UV|protein ubiquitination|protein ubiquitination|neuron projection development|response to endoplasmic reticulum stress|proteasome-mediated ubiquitin-dependent protein catabolic process|cellular protein catabolic process|protein autoubiquitination|,ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|ATP binding|ubiquitin-ubiquitin ligase activity|,9,-0.1,0.229,9,0.9,5.27,0.8,2.38,2.38,0.448,0,0,-0.3,2
ENSMUSG00000066975,CRYBA4,"crystallin, beta A4",None,visual perception|camera-type eye development|,structural constituent of eye lens|,10,-0.2,0.324,10,0.5,4.56,0.5,2.38,2.38,0.448,0,0,-0.6,1.7
ENSMUSG00000055780,USP26,ubiquitin specific peptidase 26,nucleus|,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,-0.4,2.37,10,-0.2,0.737,-0.4,2.37,-2.37,0.449,0,0,-1.7,0.5
ENSMUSG00000031232,MAGT1,magnesium transporter 1,endoplasmic reticulum|plasma membrane|oligosaccharyltransferase complex|membrane|membrane|integral component of membrane|,transport|magnesium ion transport|ion transmembrane transport|cell redox homeostasis|cognition|,magnesium ion transmembrane transporter activity|,9,0.5,1.37,9,0.3,1.44,0.3,2.37,2.37,0.449,0,0,-0.6,1.7
ENSMUSG00000029352,CRYBB3,"crystallin, beta B3",None,None,structural constituent of eye lens|,10,0,0,10,0.3,3.56,0.2,2.37,2.37,0.449,0,0,-1.5,1.2
ENSMUSG00000036854,HSPB6,"heat shock protein, alpha-crystallin-related, B6",nucleus|cytoplasm|,response to stress|,structural constituent of eye lens|protein homodimerization activity|,10,-0.4,3.61,10,-0.1,0.0902,-0.3,2.36,-2.36,0.45,0,0,-1.7,0.4
ENSMUSG00000031594,FGL1,fibrinogen-like protein 1,extracellular region|extracellular vesicular exosome|,cholesterol metabolic process|regulation of glucose metabolic process|adipose tissue development|,None,10,0.1,0.543,10,0.4,2.49,0.3,2.34,2.34,0.453,0,0,-0.7,1.5
ENSMUSG00000068008,BPIFB3,"BPI fold containing family B, member 3",extracellular region|cytoplasm|,biological_process|,lipid binding|,10,-1.1,4.38,10,0.4,0.934,0.4,2.34,2.34,0.453,0,0,-2,1
ENSMUSG00000005142,MAN2B1,"mannosidase 2, alpha B1",lysosome|extracellular vesicular exosome|,carbohydrate metabolic process|mannose metabolic process|mannose metabolic process|cellular protein modification process|learning or memory|metabolic process|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-mannosidase activity|alpha-mannosidase activity|alpha-mannosidase activity|mannose binding|zinc ion binding|mannosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|metal ion binding|",10,-0.7,3.62,10,-0.1,0.23,-0.6,2.33,-2.33,0.454,0,0,-1.9,0.5
ENSMUSG00000035699,SLC51A,"solute carrier family 51, alpha subunit",endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|protein complex|,transport|transport|bile acid and bile salt transport|,transporter activity|transporter activity|protein binding|protein homodimerization activity|protein heterodimerization activity|,10,0.4,2.71,10,0.1,0.214,0.3,2.33,2.33,0.454,0,0,-0.4,1.6
ENSMUSG00000059901,ADAMTS14,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14",extracellular region|,proteolysis|integrin-mediated signaling pathway|collagen fibril organization|,peptidase activity|,10,0.5,2.17,10,0.2,1.22,0.3,2.31,2.31,0.457,0,0,-0.3,1.7
ENSMUSG00000020064,HERC4,hect domain and RLD 4,nucleus|cytoplasm|,spermatogenesis|protein ubiquitination|cell differentiation|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,1.09,10,0.3,2.08,0.3,2.31,2.31,0.457,0,0,-0.8,1.6
ENSMUSG00000022580,RHPN1,"rhophilin, Rho GTPase binding protein 1",None,signal transduction|regulation of catalytic activity|,small GTPase regulator activity|,10,0.3,1.24,10,0.3,1.23,0.3,2.29,2.29,0.459,0,0,-0.4,1.5
ENSMUSG00000074093,SVIP,small VCP/p97-interacting protein,Hrd1p ubiquitin ligase complex|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|plasma membrane|membrane|extracellular vesicular exosome|,positive regulation of autophagy|negative regulation of protein complex assembly|positive regulation of protein lipidation|negative regulation of ER-associated ubiquitin-dependent protein catabolic process|,protein self-association|,10,-0.1,0.135,10,0.9,4.72,0.4,2.28,2.28,0.46,0,0,-0.3,1.9
ENSMUSG00000057182,SCN3A,"sodium channel, voltage-gated, type III, alpha",voltage-gated sodium channel complex|cytoplasm|plasma membrane|membrane|integral component of membrane|axon|neuronal cell body|,transport|ion transport|potassium ion transport|sodium ion transport|neuronal action potential|neuronal action potential|sensory perception of pain|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|response to pyrethroid|cellular response to antibiotic|potassium ion transmembrane transport|membrane depolarization during action potential|,voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|potassium channel activity|sodium channel activity|calmodulin binding|sodium ion binding|,10,0.2,0.749,10,0.3,1.74,0.2,2.26,2.26,0.462,0,0,-0.8,1.5
ENSMUSG00000022844,PDIA5,protein disulfide isomerase associated 5,endoplasmic reticulum|,protein folding|response to endoplasmic reticulum stress|cell redox homeostasis|,protein disulfide isomerase activity|isomerase activity|,10,-0.3,3.48,10,0,0,-0.3,2.22,-2.22,0.467,0,0,-1.6,0.6
ENSMUSG00000028063,LMNA,lamin A,intracellular|cell|nucleus|nucleus|nuclear envelope|nuclear envelope|lamin filament|cytoplasm|intermediate filament|nuclear matrix|perinuclear region of cytoplasm|,nucleus organization|nuclear envelope organization|muscle organ development|establishment of cell polarity|regulation of cell migration|establishment or maintenance of microtubule cytoskeleton polarity|protein localization to nucleus|sterol regulatory element binding protein import into nucleus|ventricular cardiac muscle cell development|negative regulation of release of cytochrome c from mitochondria|positive regulation of cell aging|regulation of protein localization to nucleus|negative regulation of extrinsic apoptotic signaling pathway|,structural molecule activity|protein binding|,10,0,0,10,0.4,2.94,0.3,2.22,2.22,0.467,0,0,-0.2,1.9
ENSMUSG00000090019,GIMAP1,"GTPase, IMAP family member 1",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,B cell differentiation|T cell differentiation|,nucleotide binding|GTP binding|,10,-0.3,3.25,10,0.2,0.883,-0.2,2.22,-2.22,0.467,0,0,-1.3,1.1
ENSMUSG00000025980,HSPD1,heat shock protein 1 (chaperonin),extracellular space|cytoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|early endosome|rough endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|coated pit|cell surface|membrane|cyclin-dependent protein kinase activating kinase holoenzyme complex|mitochondrial crista|coated vesicle|secretory granule|secretory granule|secretory granule|zymogen granule|intracellular membrane-bounded organelle|protein complex|membrane raft|lipopolysaccharide receptor complex|extracellular vesicular exosome|,detection of misfolded protein|B cell cytokine production|MyD88-dependent toll-like receptor signaling pathway|positive regulation of T cell mediated immune response to tumor cell|protein folding|activation of cysteine-type endopeptidase activity involved in apoptotic process|response to unfolded protein|positive regulation of interferon-alpha production|positive regulation of interferon-alpha production|positive regulation of interferon-gamma production|positive regulation of interferon-gamma production|positive regulation of interferon-gamma production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-6 production|protein refolding|B cell proliferation|T cell activation|T cell activation|T cell activation|B cell activation|positive regulation of macrophage activation|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|cellular protein metabolic process|isotype switching to IgG isotypes|positive regulation of inflammatory response|protein stabilization|positive regulation of T cell activation|positive regulation of T cell activation|chaperone mediated protein folding requiring cofactor|,nucleotide binding|lipopolysaccharide binding|lipopolysaccharide binding|protease binding|p53 binding|double-stranded RNA binding|ATP binding|protein complex binding|insulin binding|poly(A) RNA binding|protein heterodimerization activity|chaperone binding|misfolded protein binding|,10,1.1,2.65,9,-0.2,0.435,-0.3,2.22,-2.22,0.467,0,0,-1.1,1.9
ENSMUSG00000052934,FBXO31,F-box protein 31,SCF ubiquitin ligase complex|,cellular response to DNA damage stimulus|cell cycle|cyclin catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|mitotic G1 DNA damage checkpoint|,cyclin binding|,10,-0.2,1.03,10,-0.4,1.9,-0.2,2.2,-2.2,0.469,0,0,-1.6,0.5
ENSMUSG00000049076,ACAP2,"ArfGAP with coiled-coil, ankyrin repeat and PH domains 2",ruffle|endosome|endosome membrane|membrane|membrane|,actin filament-based process|regulation of ARF GTPase activity|protein localization to endosome|positive regulation of GTPase activity|cellular response to nerve growth factor stimulus|,GTPase activator activity|protein binding|ARF GTPase activator activity|zinc ion binding|Rab GTPase binding|metal ion binding|,10,0,0,10,0.3,2.49,0.3,2.19,2.19,0.47,0,0,-0.3,1.7
ENSMUSG00000074746,PDZD8,PDZ domain containing 8,membrane|,cytoskeleton organization|regulation of cell morphogenesis|,molecular_function|metal ion binding|,10,-0.3,1.57,10,-0.3,0.791,-0.3,2.19,-2.19,0.47,0,0,-1.6,0.5
ENSMUSG00000039278,PCSK1N,proprotein convertase subtilisin/kexin type 1 inhibitor,extracellular region|extracellular space|extracellular space|Golgi apparatus|trans-Golgi network|secretory granule|extracellular vesicular exosome|,response to dietary excess|neuropeptide signaling pathway|response to cold|negative regulation of endopeptidase activity|peptide hormone processing|,endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|,10,0.5,3.56,10,0.1,0.172,0.3,2.19,2.19,0.47,0,0,-1.2,1.5
ENSMUSG00000004460,DNAJB11,"DnaJ (Hsp40) homolog, subfamily B, member 11",nucleus|nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|membrane|,protein folding|mRNA modification|mRNA modification|,protein binding|unfolded protein binding|,10,-0.6,4.91,10,0,0,-0.6,2.18,-2.18,0.472,0,0,-1.9,0.3
ENSMUSG00000022768,CCDC116,coiled-coil domain containing 116,cellular_component|,biological_process|,molecular_function|,10,0.1,0.223,10,0.3,2.23,0.2,2.17,2.17,0.473,0,0,-0.5,1.6
ENSMUSG00000017765,SLC12A4,"solute carrier family 12, member 4",lysosomal membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|transmembrane transport|,transporter activity|symporter activity|cation:chloride symporter activity|potassium:chloride symporter activity|protein kinase binding|,10,0.1,0.0411,10,0.5,3.69,0.4,2.16,2.16,0.474,0,0,-0.6,1.7
ENSMUSG00000022075,RHOBTB2,Rho-related BTB domain containing 2,cellular_component|intracellular|,small GTPase mediated signal transduction|,nucleotide binding|protein binding|GTP binding|,10,0.4,2.17,10,0.2,0.631,0.3,2.15,2.15,0.475,0,0,-0.4,1.6
ENSMUSG00000063904,DPP3,dipeptidylpeptidase 3,nucleus|cytoplasm|plasma membrane|extracellular vesicular exosome|,proteolysis|,aminopeptidase activity|peptidase activity|metallopeptidase activity|dipeptidyl-peptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.4,1.93,10,0.2,0.865,0.2,2.14,2.14,0.477,0,0,-0.6,1.6
ENSMUSG00000039521,FOXP3,forkhead box P3,intracellular|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|B cell homeostasis|cytokine production|cytokine production|cytokine production|myeloid cell homeostasis|CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|T cell mediated immunity|tolerance induction|tolerance induction to self antigen|regulation of immunoglobulin production|positive regulation of T cell tolerance induction|positive regulation of T cell anergy|negative regulation of chronic inflammatory response|negative regulation of chronic inflammatory response|negative regulation of T cell cytokine production|positive regulation of peripheral T cell tolerance induction|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of cell proliferation|positive regulation of gene expression|negative regulation of histone deacetylation|negative regulation of NF-kappaB transcription factor activity|negative regulation of interferon-gamma production|negative regulation of interferon-gamma production|negative regulation of interferon-gamma production|negative regulation of interleukin-10 production|negative regulation of interleukin-10 production|negative regulation of interleukin-2 production|negative regulation of interleukin-2 production|negative regulation of interleukin-4 production|negative regulation of interleukin-4 production|negative regulation of interleukin-4 production|negative regulation of interleukin-5 production|negative regulation of interleukin-5 production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|positive regulation of interleukin-4 production|negative regulation of CREB transcription factor activity|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of transforming growth factor beta1 production|positive regulation of immature T cell proliferation in thymus|positive regulation of histone acetylation|positive regulation of histone acetylation|negative regulation of histone acetylation|negative regulation of cytokine biosynthetic process|T cell activation|T cell activation|negative regulation of T cell proliferation|negative regulation of T cell proliferation|negative regulation of T cell proliferation|negative regulation of sequence-specific DNA binding transcription factor activity|regulatory T cell differentiation|regulatory T cell differentiation|negative regulation of interferon-gamma biosynthetic process|negative regulation of interleukin-2 biosynthetic process|negative regulation of interleukin-2 biosynthetic process|positive regulation of regulatory T cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of isotype switching to IgE isotypes|regulation of isotype switching to IgG isotypes|negative regulation of lymphocyte proliferation|negative regulation of cytokine secretion|negative regulation of inflammatory response|negative regulation of immune response|T cell receptor signaling pathway|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription corepressor activity|histone acetyltransferase binding|protein homodimerization activity|protein homodimerization activity|histone deacetylase binding|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|NFAT protein binding|,10,0.1,0.112,10,-0.5,4.52,-0.4,2.13,-2.13,0.478,0,0,-1.6,0.5
ENSMUSG00000030499,KCTD15,potassium channel tetramerisation domain containing 15,cellular_component|,multicellular organismal development|biological_process|protein homooligomerization|,molecular_function|,10,-0.4,2.78,10,-0.1,0.142,-0.3,2.13,-2.13,0.478,0,0,-1.6,0.8
ENSMUSG00000074403,HIST2H3B,"histone cluster 2, H3b",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,None,4,-0.9,3.39,4,0.3,1.66,0.7,2.12,2.12,0.479,0,0,-1.8,1.8
ENSMUSG00000016942,TMPRSS6,transmembrane serine protease 6,plasma membrane|plasma membrane|membrane|integral component of membrane|,proteolysis|fibrinolysis|iron ion homeostasis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,1,4.79,1,2.12,2.12,0.479,0,0,0,2
ENSMUSG00000034579,PLA2G3,"phospholipase A2, group III",extracellular region|intracellular|cell|centriole|mast cell granule|,acrosome assembly|sperm axoneme assembly|lipoxygenase pathway|mast cell degranulation|phosphatidylcholine metabolic process|cell development|cilium morphogenesis|,molecular_function|,9,-0.3,2.49,9,0.2,0.85,-0.3,2.11,-2.11,0.481,0,0,-1.6,0.9
ENSMUSG00000028370,PAPPA,pregnancy-associated plasma protein A,extracellular region|extracellular space|membrane|,proteolysis|proteolysis|cell differentiation|response to glucocorticoid|,endopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.2,1.32,10,0.4,1.13,0.3,2.09,2.09,0.483,0,0,-0.6,1.6
ENSMUSG00000023232,SERINC2,serine incorporator 2,membrane|integral component of membrane|extracellular vesicular exosome|,phosphatidylserine metabolic process|positive regulation of transferase activity|,molecular_function|,10,0.8,0.842,10,0.2,1.89,0.2,2.09,2.09,0.483,0,0,-0.5,1.8
ENSMUSG00000001829,CLPB,ClpB caseinolytic peptidase B,mitochondrion|,cellular response to heat|,nucleotide binding|ATP binding|,10,-0.3,3.38,10,0,0,-0.2,2.08,-2.08,0.485,0,0,-1.5,0.9
ENSMUSG00000002633,SHH,sonic hedgehog,extracellular region|extracellular space|extracellular space|nucleus|endoplasmic reticulum|Golgi apparatus|plasma membrane|cell surface|membrane|transport vesicle|axon|dendrite|extracellular matrix|neuronal cell body|membrane raft|membrane raft|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|angiogenesis|angiogenesis|angiogenesis|patterning of blood vessels|vasculogenesis|metanephros development|branching involved in ureteric bud morphogenesis|cell fate specification|cell fate specification|cell fate specification|neural crest cell migration|kidney development|neural tube formation|hair follicle development|vasculature development|heart looping|positive regulation of neuroblast proliferation|positive regulation of neuroblast proliferation|positive regulation of mesenchymal cell proliferation|osteoblast development|lymphoid progenitor cell differentiation|lymphoid progenitor cell differentiation|determination of left/right asymmetry in lateral mesoderm|regulation of transcription, DNA-templated|proteolysis|endocytosis|apoptotic process|cell communication|signal transduction|smoothened signaling pathway|smoothened signaling pathway|smoothened signaling pathway|positive regulation of hh target transcription factor activity|positive regulation of hh target transcription factor activity|positive regulation of hh target transcription factor activity|cell-cell signaling|multicellular organismal development|determination of left/right symmetry|pattern specification process|pattern specification process|ectoderm development|neuroblast proliferation|axon guidance|axon guidance|central nervous system development|hindgut morphogenesis|digestive tract mesoderm development|heart development|blood coagulation|androgen metabolic process|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|embryo development|embryo development|polarity specification of anterior/posterior axis|anterior/posterior pattern specification|dorsal/ventral pattern formation|mesenchymal cell proliferation|regulation of gene expression|regulation of gene expression|regulation of gene expression|regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|oligodendrocyte development|striated muscle tissue development|positive regulation of skeletal muscle cell proliferation|myotube differentiation|intein-mediated protein splicing|spinal cord dorsal/ventral patterning|spinal cord dorsal/ventral patterning|ventral spinal cord interneuron specification|spinal cord motor neuron differentiation|thalamus development|thalamus development|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|cerebellar granule cell precursor proliferation|smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation|smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation|positive regulation of cerebellar granule cell precursor proliferation|telencephalon regionalization|telencephalon regionalization|establishment of cell polarity|regulation of proteolysis|positive regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|respiratory tube development|lung development|lung development|embryonic limb morphogenesis|embryonic limb morphogenesis|negative regulation of cell migration|male genitalia development|prostate gland development|thyroid gland development|forebrain development|midbrain development|hindbrain development|hindbrain development|pancreas development|pancreas development|hair follicle morphogenesis|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|T cell differentiation in thymus|positive regulation of T cell differentiation in thymus|positive regulation of immature T cell proliferation in thymus|negative regulation of transcription elongation from RNA polymerase II promoter|protein localization to nucleus|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|regulation of cell proliferation|regulation of cell proliferation|negative regulation of T cell proliferation|negative regulation of protein catabolic process|positive regulation of protein import into nucleus|odontogenesis of dentin-containing tooth|odontogenesis|regulation of odontogenesis|embryonic digit morphogenesis|embryonic digit morphogenesis|camera-type eye development|camera-type eye development|camera-type eye development|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|CD4-positive or CD8-positive, alpha-beta T cell lineage commitment|CD4-positive or CD8-positive, alpha-beta T cell lineage commitment|tongue development|tongue morphogenesis|skin development|positive thymic T cell selection|negative thymic T cell selection|intermediate filament organization|cell fate commitment|myoblast differentiation|response to ethanol|negative regulation of cell differentiation|negative regulation of cell differentiation|positive regulation of cell differentiation|positive regulation of neuron differentiation|positive regulation of smoothened signaling pathway|positive regulation of smoothened signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of photoreceptor cell differentiation|positive regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T cell differentiation|cell development|thymus development|digestive tract morphogenesis|embryonic digestive tract morphogenesis|embryonic digestive tract morphogenesis|embryonic organ development|developmental growth|embryonic morphogenesis|embryonic foregut morphogenesis|positive regulation of skeletal muscle tissue development|organ formation|anatomical structure formation involved in morphogenesis|neuron fate commitment|response to axon injury|embryonic skeletal system development|oligodendrocyte differentiation|positive regulation of oligodendrocyte differentiation|branching morphogenesis of an epithelial tube|male genitalia morphogenesis|inner ear development|inner ear development|anatomical structure development|formation of anatomical boundary|stem cell development|striated muscle cell differentiation|striated muscle cell differentiation|positive regulation of striated muscle cell differentiation|positive regulation of cell division|Bergmann glial cell differentiation|palate development|canonical Wnt signaling pathway|limb development|limb development|limb bud formation|positive regulation of penile erection|lung morphogenesis|lung epithelium development|trachea development|trachea morphogenesis|epithelial tube branching involved in lung morphogenesis|branching involved in prostate gland morphogenesis|branching involved in salivary gland morphogenesis|branching involved in salivary gland morphogenesis|bud outgrowth involved in lung branching|right lung development|left lung development|lung lobe morphogenesis|lung-associated mesenchyme development|primary prostatic bud elongation|prostate epithelial cord elongation|salivary gland cavitation|epithelial cell proliferation involved in salivary gland morphogenesis|epithelial-mesenchymal cell signaling|regulation of prostatic bud formation|regulation of prostatic bud formation|epithelial-mesenchymal signaling involved in prostate gland development|epithelial-mesenchymal signaling involved in prostate gland development|regulation of epithelial cell proliferation involved in prostate gland development|positive regulation of epithelial cell proliferation involved in prostate gland development|regulation of mesenchymal cell proliferation involved in prostate gland development|mesenchymal smoothened signaling pathway involved in prostate gland development|artery development|artery development|mesenchymal cell proliferation involved in lung development|vasculogenesis involved in coronary vascular morphogenesis|somite development|positive regulation of sclerotome development|fungiform papilla development|fungiform papilla morphogenesis|fungiform papilla formation|positive regulation of oligodendrocyte progenitor proliferation|cellular response to lithium ion|metanephric mesenchymal cell proliferation involved in metanephros development|multicellular structure septum development|negative regulation of canonical Wnt signaling pathway|negative regulation of cholesterol efflux|apoptotic signaling pathway|regulation of protein localization to nucleus|negative regulation of ureter smooth muscle cell differentiation|positive regulation of ureter smooth muscle cell differentiation|negative regulation of kidney smooth muscle cell differentiation|positive regulation of kidney smooth muscle cell differentiation|positive regulation of mesenchymal cell proliferation involved in ureter development|negative regulation of mesenchymal cell apoptotic process|",glycoprotein binding|patched binding|patched binding|calcium ion binding|protein binding|glycosaminoglycan binding|peptidase activity|zinc ion binding|laminin-1 binding|metal ion binding|,10,-0.9,1.87,10,-0.3,1.11,-0.2,2.08,-2.08,0.485,0,0,-2,0.2
ENSMUSG00000038365,FBXO25,F-box protein 25,nucleus|nucleus|SCF ubiquitin ligase complex|,protein ubiquitination|,actin binding|protein binding|,10,-0.8,4.85,10,0.4,2.01,-0.8,2.07,-2.07,0.486,0,0,-2,0.7
ENSMUSG00000038751,PTK6,PTK6 protein tyrosine kinase 6,ruffle|nucleus|nucleus|cytoplasm|membrane|cell projection|,protein phosphorylation|positive regulation of neuron projection development|phosphorylation|cell migration|tyrosine phosphorylation of Stat3 protein|tyrosine phosphorylation of Stat5 protein|negative regulation of growth|protein autophosphorylation|intestinal epithelial cell differentiation|negative regulation of protein tyrosine kinase activity|cellular response to retinoic acid|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|",10,0.2,0.787,10,0.7,3.7,0.5,2.07,2.07,0.486,0,0,-0.3,1.9
ENSMUSG00000019124,SCRN1,secernin 1,nucleus|cytoplasm|nuclear membrane|,proteolysis|exocytosis|biological_process|,molecular_function|dipeptidase activity|,10,-0.2,1.73,10,-0.1,0.499,-0.2,2.06,-2.06,0.487,0,0,-1.4,0.9
ENSMUSG00000040026,SAA3,serum amyloid A 3,extracellular region|high-density lipoprotein particle|,acute-phase response|,None,10,0.4,1.25,10,0.2,1.19,0.3,2.06,2.06,0.487,0,0,-0.5,1.7
ENSMUSG00000034813,GRIP1,glutamate receptor interacting protein 1,endoplasmic reticulum|plasma membrane|membrane|cell junction|dendrite|cytoplasmic vesicle|neuron projection|neuronal cell body|membrane raft|synapse|postsynaptic membrane|recycling endosome|,nervous system development|protein localization|protein transport|,protein binding|protein C-terminus binding|,10,-0.3,2.46,10,-0.1,0.00171,-0.3,2.06,-2.06,0.487,0,0,-1.5,0.7
ENSMUSG00000050103,AGMO,alkylglycerol monooxygenase,endoplasmic reticulum|membrane|integral component of membrane|,fatty acid biosynthetic process|membrane lipid metabolic process|ether lipid metabolic process|oxidation-reduction process|,iron ion binding|oxidoreductase activity|glyceryl-ether monooxygenase activity|,10,1,0.628,10,1.1,1.59,1.1,2.05,2.05,0.489,0,0,-0.2,2
ENSMUSG00000075604,CYP11B1,"cytochrome P450, family 11, subfamily b, polypeptide 1",mitochondrion|mitochondrion|,regulation of blood volume by renal aldosterone|C21-steroid hormone biosynthetic process|glucocorticoid biosynthetic process|glucocorticoid biosynthetic process|aldosterone biosynthetic process|potassium ion homeostasis|sodium ion homeostasis|oxidation-reduction process|,monooxygenase activity|steroid 11-beta-monooxygenase activity|oxidoreductase activity|heme binding|metal ion binding|corticosterone 18-monooxygenase activity|corticosterone 18-monooxygenase activity|,10,0.3,1.27,10,-0.8,4.99,-0.7,2.05,-2.05,0.489,0,0,-2,0.6
ENSMUSG00000042359,OSBPL6,oxysterol binding protein-like 6,cytosol|plasma membrane|nuclear membrane|perinuclear endoplasmic reticulum|,transport|lipid transport|biological_process|,molecular_function|lipid binding|,10,0.7,3.74,10,-0.1,0.142,0.5,2.05,2.05,0.489,0,0,-0.4,1.8
ENSMUSG00000043008,KLHL6,kelch-like 6,cellular_component|,germinal center formation|B cell receptor signaling pathway|,molecular_function|,10,0.4,3.17,10,-0.1,0.51,0.4,2.04,2.04,0.49,0,0,-0.6,1.6
ENSMUSG00000034243,GOLGB1,"golgi autoantigen, golgin subfamily b, macrogolgin 1",endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|Golgi apparatus|cis-Golgi network|membrane|,biological_process|,poly(A) RNA binding|,10,0.4,1.47,10,0.2,0.866,0.2,2.03,2.03,0.491,0,0,-0.5,1.7
ENSMUSG00000034757,TMUB2,transmembrane and ubiquitin-like domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.284,10,0.4,2.05,0.3,2.02,2.02,0.493,0,0,-0.4,1.7
ENSMUSG00000002565,SCIN,scinderin,cytoplasm|cytoskeleton|protein complex|extracellular vesicular exosome|,negative regulation of cell proliferation|positive regulation of apoptotic process|positive regulation of megakaryocyte differentiation|actin filament severing|actin filament capping|,actin binding|,10,0.4,2.19,10,0.2,0.46,0.3,2.02,2.02,0.493,0,0,-0.9,1.6
ENSMUSG00000032220,MYO1E,myosin IE,cytoplasm|cytoskeleton|cell-cell junction|adherens junction|myosin complex|cell junction|cytoplasmic vesicle|protein complex|clathrin-coated endocytic vesicle|extracellular vesicular exosome|,vasculogenesis|in utero embryonic development|kidney development|glomerular filtration|ATP catabolic process|nitrogen compound metabolic process|endocytosis|hemopoiesis|glomerular basement membrane development|post-embryonic hemopoiesis|platelet-derived growth factor receptor signaling pathway|glomerular visceral epithelial cell development|,"nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|lipid binding|protein complex binding|phosphatidylinositol binding|ATPase activity, coupled|actin filament binding|",10,-0.1,0.299,10,0.7,4.39,0.6,2.02,2.02,0.493,0,0,-0.7,1.9
ENSMUSG00000020256,ALDH1L2,"aldehyde dehydrogenase 1 family, member L2",cytoplasm|mitochondrion|mitochondrion|,one-carbon metabolic process|metabolic process|biosynthetic process|10-formyltetrahydrofolate catabolic process|oxidation-reduction process|,"catalytic activity|methyltransferase activity|formyltetrahydrofolate dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|hydroxymethyl-, formyl- and related transferase activity|",10,-0.3,2.18,10,-0.1,0.434,-0.2,2.01,-2.01,0.494,0,0,-1.6,0.6
ENSMUSG00000024430,CABYR,calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2),intracellular|nucleus|cytoplasm|cytoplasm|cytoskeleton|cilium|motile cilium|motile cilium|sperm fibrous sheath|sperm fibrous sheath|cell projection|sperm principal piece|sperm end piece|,calcium-mediated signaling|sperm capacitation|protein oligomerization|,calcium ion binding|calcium ion binding|calcium ion binding|protein binding|enzyme binding|protein domain specific binding|metal ion binding|protein heterodimerization activity|,10,0.2,1.31,10,0.4,1.26,0.2,1.99,1.99,0.497,0,0,-0.3,2
ENSMUSG00000015890,AMDHD1,amidohydrolase domain containing 1,cytoplasm|,histidine metabolic process|histidine catabolic process to glutamate and formamide|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|metal ion binding|imidazolonepropionase activity|",10,-0.3,1.14,10,-0.4,1.17,-0.3,1.99,-1.99,0.497,0,0,-1.6,0.5
ENSMUSG00000063077,KIF1B,kinesin family member 1B,intracellular|cell|cytoplasm|mitochondrion|cytoskeleton|kinesin complex|microtubule|microtubule associated complex|cytoplasmic vesicle membrane|cytoplasmic vesicle|neuron projection|,ATP catabolic process|microtubule-based movement|neuron-neuron synaptic transmission|neuromuscular synaptic transmission|anterograde axon cargo transport|embryo development|cytoskeleton-dependent intracellular transport|mitochondrion transport along microtubule|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|ATPase activity|,10,-0.1,0.0234,10,-0.3,2.22,-0.3,1.99,-1.99,0.497,0,0,-1.5,1.1
ENSMUSG00000021629,SLC30A5,"solute carrier family 30 (zinc transporter), member 5",nucleus|nucleolus|Golgi apparatus|Golgi apparatus|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|secretory granule|,transport|ion transport|cation transport|cobalt ion transport|zinc ion transport|zinc ion transport|cellular zinc ion homeostasis|response to zinc ion|transmembrane transport|zinc ion transmembrane transport|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|zinc ion transmembrane transporter activity|cation transmembrane transporter activity|,10,-0.3,1.56,10,0.2,0.982,0.3,1.99,1.99,0.497,0,0,-1.1,1.3
ENSMUSG00000092192,DYX1C1,dyslexia susceptibility 1 candidate 1 homolog (human),nucleus|cytoplasm|cytoplasm|plasma membrane|,neuron migration|cilium movement|cilium movement|determination of left/right symmetry|determination of left/right symmetry|nervous system development|regulation of intracellular estrogen receptor signaling pathway|outer dynein arm assembly|outer dynein arm assembly|inner dynein arm assembly|inner dynein arm assembly|regulation of proteasomal protein catabolic process|,protein binding|estrogen receptor binding|,9,0.5,1.41,9,0.2,0.969,0.3,1.98,1.98,0.498,0,0,-0.7,1.7
ENSMUSG00000038086,HSPB2,heat shock protein 2,nucleus|cytoplasm|,response to stress|somatic muscle development|response to heat|,None,10,-0.1,0.21,10,-0.5,2.47,-0.4,1.97,-1.97,0.499,0,0,-1.9,0.2
ENSMUSG00000012126,UBXN11,UBX domain protein 11,cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,0.6,3.77,10,0.1,0.0979,0.4,1.96,1.96,0.501,0,0,-0.4,1.8
ENSMUSG00000027938,CREB3L4,cAMP responsive element binding protein 3-like 4,nucleus|endoplasmic reticulum|membrane|integral component of membrane|cytoplasmic vesicle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to unfolded protein|multicellular organismal development|spermatogenesis|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,9,0.5,2.74,9,0.1,0.2,0.3,1.96,1.96,0.501,0,0,-0.6,1.8
ENSMUSG00000061119,PRCP,prolylcarboxypeptidase (angiotensinase C),lysosome|basal part of cell|extracellular vesicular exosome|,regulation of thyroid hormone mediated signaling pathway|plasma kallikrein-kinin cascade|negative regulation of systemic arterial blood pressure|proteolysis|glucose homeostasis|regulation of blood vessel endothelial cell migration|regulation of blood vessel endothelial cell migration|angiogenesis involved in wound healing|energy homeostasis|regulation of reactive oxygen species metabolic process|,molecular_function|carboxypeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.4,2.34,10,0.1,0.198,0.3,1.95,1.95,0.502,0,0,-0.9,1.6
ENSMUSG00000037727,AVP,arginine vasopressin,extracellular region|extracellular space|secretory granule|dendrite|,maternal aggressive behavior|positive regulation of systemic arterial blood pressure|protein phosphorylation|signal transduction|positive regulation of cytosolic calcium ion concentration|negative regulation of female receptivity|grooming behavior|locomotory behavior|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of glutamate secretion|positive regulation of cell growth|positive regulation of cAMP biosynthetic process|positive regulation of prostaglandin biosynthetic process|positive regulation of cellular pH reduction|positive regulation of peptidyl-serine phosphorylation|social behavior|regulation of renal sodium excretion|vasoconstriction|maternal behavior|negative regulation of apoptotic process|penile erection|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of vasoconstriction|regulation of blood vessel size|multicellular organismal water homeostasis|negative regulation of transmission of nerve impulse|ERK1 and ERK2 cascade|protein kinase C signaling|negative regulation of release of cytochrome c from mitochondria|,protein kinase activity|signal transducer activity|hormone activity|neuropeptide hormone activity|neurohypophyseal hormone activity|V1A vasopressin receptor binding|V1B vasopressin receptor binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|,10,-0.4,2.3,10,-0.2,0.0497,-0.3,1.95,-1.95,0.502,0,0,-1.7,0.4
ENSMUSG00000070388,FBXO39,F-box protein 39,cellular_component|,biological_process|,molecular_function|,9,0.4,1,9,0.9,1.9,0.7,1.94,1.94,0.503,0,0,-0.2,2
ENSMUSG00000036805,NOXA1,NADPH oxidase activator 1,cytoplasm|plasma membrane|membrane|NADPH oxidase complex|,superoxide metabolic process|superoxide metabolic process|regulation of hydrogen peroxide metabolic process|positive regulation of catalytic activity|positive regulation of catalytic activity|regulation of respiratory burst|,superoxide-generating NADPH oxidase activator activity|superoxide-generating NADPH oxidase activator activity|SH3 domain binding|enzyme binding|Rac GTPase binding|,10,0.1,0.489,10,0.5,2.58,0.4,1.9,1.9,0.509,0,0,-1.2,1.8
ENSMUSG00000021712,TRIM23,tripartite motif-containing 23,Golgi membrane|intracellular|nucleus|cytoplasm|lysosome|lysosomal membrane|Golgi apparatus|membrane|extracellular vesicular exosome|,GTP catabolic process|protein ADP-ribosylation|small GTPase mediated signal transduction|protein ubiquitination|,"nucleotide binding|GTPase activity|ubiquitin-protein transferase activity|GTP binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|GDP binding|identical protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.101,10,-0.2,2.01,-0.2,1.9,-1.9,0.509,0,0,-1.6,1.2
ENSMUSG00000059256,GZMD,granzyme D,membrane|,cytolysis|,catalytic activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.3,1.07,10,-0.3,0.987,-0.3,1.9,-1.9,0.509,0,0,-1.8,0.6
ENSMUSG00000034620,TMEM5,transmembrane protein 5,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.26,10,0.3,0.793,0.2,1.86,1.86,0.515,0,0,-0.6,1.7
ENSMUSG00000030881,ARFIP2,ADP-ribosylation factor interacting protein 2,ruffle|cell cortex|,actin cytoskeleton organization|,protein binding|protein domain specific binding|GTP-dependent protein binding|,10,-0.2,2.56,10,0,0,-0.2,1.86,-1.86,0.515,0,0,-1.4,1
ENSMUSG00000004610,ETFB,"electron transferring flavoprotein, beta polypeptide",mitochondrion|mitochondrion|mitochondrial electron transfer flavoprotein complex|intracellular membrane-bounded organelle|extracellular vesicular exosome|,transport|oxidation-reduction process|,electron carrier activity|,10,-0.2,1.62,10,0.2,0.637,-0.2,1.83,-1.83,0.519,0,0,-1.5,1
ENSMUSG00000054099,SLC25A40,"solute carrier family 25, member 40",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0.3,0.512,10,0.3,1.46,0.3,1.83,1.83,0.519,0,0,-1,1.5
ENSMUSG00000022534,MEFV,Mediterranean fever,intracellular|nucleus|cytoplasm|cytoskeleton|microtubule|microtubule associated complex|cell projection|,immune system process|inflammatory response|negative regulation of interleukin-1 beta production|negative regulation of interleukin-12 production|innate immune response|negative regulation of inflammatory response|negative regulation of macrophage inflammatory protein 1 alpha production|positive regulation of cysteine-type endopeptidase activity|,actin binding|zinc ion binding|metal ion binding|,9,-0.2,1.37,9,0.6,2.76,0.5,1.82,1.82,0.52,0,0,-0.6,1.9
ENSMUSG00000062683,ATP5G2,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)",mitochondrion|,biological_process|,molecular_function|,6,0,0,6,0.6,3.77,0.5,1.81,1.81,0.522,0,0,-0.6,2
ENSMUSG00000029510,GPC2,glypican 2 (cerebroglycan),extracellular region|proteinaceous extracellular matrix|endoplasmic reticulum|plasma membrane|membrane|anchored component of membrane|,smoothened signaling pathway|neuron differentiation|,heparan sulfate proteoglycan binding|,10,0.2,0.168,10,1.4,3.86,1.3,1.8,1.8,0.523,0,0,-0.1,2
ENSMUSG00000028488,SH3GL2,SH3-domain GRB2-like 2,cell|cytoplasm|membrane|extracellular vesicular exosome|,regulation of receptor internalization|endocytosis|synaptic vesicle endocytosis|,protein binding|lipid binding|identical protein binding|,10,-0.4,1.6,10,-0.1,0.678,-0.2,1.8,-1.8,0.523,0,0,-1.7,1.2
ENSMUSG00000031851,NTPCR,"nucleoside-triphosphatase, cancer-related",membrane|extracellular vesicular exosome|,biological_process|,"nucleotide binding|ATP binding|hydrolase activity|nucleoside-triphosphatase activity|poly(A) RNA binding|nucleotide phosphatase activity, acting on free nucleotides|",10,-0.3,2.22,9,-0.1,0.114,-0.3,1.79,-1.79,0.524,0,0,-1.7,0.7
ENSMUSG00000033209,TTC28,tetratricopeptide repeat domain 28,cytoplasm|centrosome|cytoskeleton|midbody|mitotic spindle|mitotic spindle pole|mitotic spindle midzone|,cell cycle|mitotic nuclear division|regulation of mitotic cell cycle|cell division|,molecular_function|,10,-0.2,1.41,10,-0.1,0.592,-0.2,1.78,-1.78,0.526,0,0,-1.5,1
ENSMUSG00000082361,BTC,"betacellulin, epidermal growth factor family member",extracellular region|plasma membrane|membrane|integral component of membrane|,epidermal growth factor receptor signaling pathway|positive regulation of cell proliferation|positive regulation of urine volume|negative regulation of apoptotic process|positive regulation of cell differentiation|positive regulation of mitosis|positive regulation of mitosis|positive regulation of fibroblast proliferation|positive regulation of cell division|,epidermal growth factor receptor binding|growth factor activity|,10,-1.1,4.7,9,0,0,-1.1,1.75,-1.75,0.531,0,0,-2,0.2
ENSMUSG00000058063,TRIM31,tripartite motif-containing 31,cellular_component|intracellular|cytoplasm|mitochondrion|,negative regulation of viral transcription|innate immune response|innate immune response|negative regulation of viral entry into host cell|negative regulation of viral entry into host cell|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of viral release from host cell|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.733,10,0.4,1.37,0.4,1.74,1.74,0.532,0,0,-0.6,1.8
ENSMUSG00000020818,MFSD11,major facilitator superfamily domain containing 11,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,3.88,10,0,0,0.4,1.73,1.73,0.533,0,0,-0.3,1.8
ENSMUSG00000041879,IPO9,importin 9,intracellular|cell|nucleus|cytoplasm|membrane|,protein import into nucleus|ribosomal protein import into nucleus|transport|intracellular protein transport|protein transport|ribosome biogenesis|protein stabilization|,Ran GTPase binding|protein transporter activity|histone binding|,10,-0.7,3.62,9,0,0,-0.6,1.73,-1.73,0.533,0,0,-1.9,0.5
ENSMUSG00000001227,SEMA6B,"sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B",plasma membrane|membrane|integral component of membrane|,multicellular organismal development|nervous system development|cell differentiation|,receptor activity|semaphorin receptor binding|,10,0.3,1.48,10,0.8,1.51,0.5,1.73,1.73,0.533,0,0,-0.2,1.8
ENSMUSG00000035696,RNF38,ring finger protein 38,nucleus|sperm flagellum|,protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,1.28,10,0.2,0.578,0.2,1.72,1.72,0.534,0,0,-0.7,1.6
ENSMUSG00000032511,SCN5A,"sodium channel, voltage-gated, type V, alpha",voltage-gated sodium channel complex|voltage-gated sodium channel complex|endoplasmic reticulum|plasma membrane|plasma membrane|caveola|cell surface|cell surface|intercalated disc|intercalated disc|membrane|integral component of membrane|T-tubule|T-tubule|sodium channel complex|sarcolemma|,regulation of heart rate|cardiac ventricle development|transport|ion transport|sodium ion transport|sodium ion transport|positive regulation of heart rate|positive regulation of sodium ion transport|response to organic cyclic compound|response to denervation involved in regulation of muscle adaptation|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|positive regulation of action potential|positive regulation of epithelial cell proliferation|membrane depolarization|transmembrane transport|cardiac muscle contraction|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of atrial cardiac muscle cell membrane depolarization|regulation of atrial cardiac muscle cell membrane repolarization|regulation of ventricular cardiac muscle cell membrane depolarization|cellular response to calcium ion|cardiac muscle cell action potential involved in contraction|regulation of cardiac muscle cell contraction|regulation of cardiac muscle cell contraction|ventricular cardiac muscle cell action potential|membrane depolarization during action potential|membrane depolarization during cardiac muscle cell action potential|SA node cell action potential|membrane depolarization during SA node cell action potential|AV node cell to bundle of His cell communication|bundle of His cell to Purkinje myocyte communication|SA node cell to atrial cardiac muscle cell communication|regulation of heart rate by cardiac conduction|regulation of heart rate by cardiac conduction|regulation of sodium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|sodium channel activity|protein binding|calmodulin binding|fibroblast growth factor binding|enzyme binding|protein kinase binding|ankyrin binding|ubiquitin protein ligase binding|ion channel binding|nitric-oxide synthase binding|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SA node cell action potential|scaffold protein binding|scaffold protein binding|,10,-0.3,1.87,10,-0.1,0.0975,-0.3,1.72,-1.72,0.534,0,0,-1.4,1.3
ENSMUSG00000048230,FBXO43,F-box protein 43,nucleus|,meiotic nuclear division|regulation of meiosis|negative regulation of protein catabolic process|negative regulation of meiosis|negative regulation of meiosis|,protein binding|zinc ion binding|metal ion binding|,8,-0.6,1.1,8,-0.2,1.7,-0.2,1.72,-1.72,0.534,0,0,-1.8,1.2
ENSMUSG00000047109,CLDN14,claudin 14,endoplasmic reticulum|plasma membrane|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,None,structural molecule activity|protein binding|,10,-0.1,0.293,10,-0.3,1.79,-0.2,1.71,-1.71,0.536,0,0,-1.5,0.8
ENSMUSG00000045027,PRSS22,"protease, serine 22",cellular_component|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.5,3.43,0.4,1.7,1.7,0.537,0,0,-0.6,1.8
ENSMUSG00000028577,PLAA,"phospholipase A2, activating protein",extracellular vesicular exosome|,inflammatory response|positive regulation of catalytic activity|,protein binding|phospholipase A2 activator activity|,10,0.4,2.46,10,0,0,0.3,1.68,1.68,0.54,0,0,-0.5,1.7
ENSMUSG00000035509,FBXL21,F-box and leucine-rich repeat protein 21,nucleus|cytoplasm|cytosol|SCF ubiquitin ligase complex|,protein ubiquitination|entrainment of circadian clock by photoperiod|rhythmic process|,protein binding|,10,0.2,0.559,10,0.5,1.81,0.3,1.67,1.67,0.542,0,0,-0.7,1.7
ENSMUSG00000040488,LTBP4,latent transforming growth factor beta binding protein 4,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|extracellular space|cell|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,transforming growth factor beta receptor signaling pathway|regulation of proteolysis|hormone secretion|,calcium ion binding|growth factor binding|transforming growth factor beta binding|,10,-0.1,0.224,10,0.4,1.91,0.3,1.66,1.66,0.543,0,0,-0.6,1.7
ENSMUSG00000026792,LRSAM1,leucine rich repeat and sterile alpha motif containing 1,cytoplasm|membrane|,protein polyubiquitination|transport|protein transport|protein catabolic process|negative regulation of endocytosis|viral budding|protein autoubiquitination|ubiquitin-dependent endocytosis|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.461,10,0.5,1.86,0.4,1.66,1.66,0.543,0,0,-0.8,1.6
ENSMUSG00000033590,MYO5C,myosin VC,myosin complex|secretory granule|,establishment of secretory granule localization|,nucleotide binding|molecular_function|ATP binding|,10,0.3,1.05,10,0.3,0.742,0.3,1.66,1.66,0.543,0,0,-0.8,1.6
ENSMUSG00000018189,UCHL5,ubiquitin carboxyl-terminal esterase L5,proteasome complex|intracellular|nucleus|cytoplasm|cytosol|Ino80 complex|Ino80 complex|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|negative regulation of endopeptidase activity|protein deubiquitination|lateral ventricle development|midbrain development|forebrain morphogenesis|regulation of proteasomal protein catabolic process|",ubiquitin-specific protease activity|endopeptidase inhibitor activity|peptidase activity|cysteine-type peptidase activity|omega peptidase activity|hydrolase activity|poly(A) RNA binding|proteasome binding|,10,0.3,2.49,10,-0.1,0.0882,0.3,1.65,1.65,0.545,0,0,-0.7,1.6
ENSMUSG00000021720,RNF180,ring finger protein 180,nucleus|endoplasmic reticulum|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|,protein polyubiquitination|adult behavior|positive regulation of protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|norepinephrine metabolic process|serotonin metabolic process|regulation of catalytic activity|organic cyclic compound metabolic process|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin conjugating enzyme binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.6,4.02,10,0,0,-0.6,1.64,-1.64,0.546,0,0,-2,0.6
ENSMUSG00000026035,PPIL3,peptidylprolyl isomerase (cyclophilin)-like 3,spliceosomal complex|catalytic step 2 spliceosome|,protein peptidyl-prolyl isomerization|mRNA processing|protein folding|RNA splicing|,peptidyl-prolyl cis-trans isomerase activity|isomerase activity|,10,0,0,10,0.3,2.46,0.2,1.63,1.63,0.547,0,0,-0.7,1.6
ENSMUSG00000030263,LRMP,lymphoid-restricted membrane protein,nucleus|chromosome|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|cytoskeleton|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,immune system process|single fertilization|biological_process|,protein binding|,10,-0.3,2.04,10,0.2,1,0.2,1.63,1.63,0.547,0,0,-1.1,1.4
ENSMUSG00000037104,SOCS5,suppressor of cytokine signaling 5,intracellular|cytoplasm|,epidermal growth factor receptor signaling pathway|negative regulation of epidermal growth factor-activated receptor activity|JAK-STAT cascade|negative regulation of signal transduction|cell growth|cytokine-mediated signaling pathway|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|intracellular signal transduction|regulation of growth|negative regulation of phosphorylation|negative regulation of catalytic activity|positive regulation of T-helper 1 cell differentiation|negative regulation of T-helper 2 cell differentiation|,epidermal growth factor receptor binding|protein binding|kinase inhibitor activity|receptor tyrosine kinase binding|,10,0.2,0.648,10,0.5,1.78,0.3,1.63,1.63,0.547,0,0,-0.4,1.8
ENSMUSG00000066151,FKBP15,FK506 binding protein 15,cytoplasm|endosome|actin filament|membrane|axon|growth cone|cell projection|,protein folding|transport|endocytosis|negative regulation of phosphatase activity|,actin binding|isomerase activity|,10,0.1,0.048,10,-0.4,3.16,-0.3,1.63,-1.63,0.547,0,0,-1.7,0.9
ENSMUSG00000022066,GM21685,"predicted gene, 21685",None,None,None,10,-0.2,0.359,10,0.5,3.64,0.4,1.61,1.61,0.55,0,0,-0.8,1.7
ENSMUSG00000004885,CRABP2,cellular retinoic acid binding protein II,nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|extracellular vesicular exosome|,transport|embryonic forelimb morphogenesis|retinoic acid metabolic process|,retinoic acid binding|transporter activity|lipid binding|retinal binding|retinol binding|cyclin binding|,10,0.2,0.589,10,-0.6,4.39,-0.5,1.6,-1.6,0.552,0,0,-1.8,0.6
ENSMUSG00000038708,GOLGA4,"golgi autoantigen, golgin subfamily a, 4",nucleus|cytoplasm|Golgi apparatus|Golgi apparatus|membrane|intracellular membrane-bounded organelle|,protein targeting to Golgi|Golgi to plasma membrane protein transport|,GTPase binding|,10,-0.1,0.414,10,0.4,3.75,0.3,1.6,1.6,0.552,0,0,-1.6,1.3
ENSMUSG00000056204,PGPEP1,pyroglutamyl-peptidase I,cytoplasm|cytosol|,proteolysis|proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|,10,-0.2,0.271,10,0.6,3.43,0.2,1.59,1.59,0.553,0,0,-0.5,1.9
ENSMUSG00000073658,CRYGB,"crystallin, gamma B",nucleus|cytoplasm|,eye development|lens development in camera-type eye|lens fiber cell development|lens fiber cell morphogenesis|,structural constituent of eye lens|,10,-0.3,3.14,10,0.3,0.905,-0.2,1.59,-1.59,0.553,0,0,-1.3,1.3
ENSMUSG00000022144,GDNF,glial cell line derived neurotrophic factor,extracellular region|extracellular space|receptor complex|,metanephros development|metanephros development|ureteric bud development|ureteric bud development|branching involved in ureteric bud morphogenesis|branching involved in ureteric bud morphogenesis|neural crest cell migration|organ induction|postsynaptic membrane organization|mesenchymal to epithelial transition involved in metanephros morphogenesis|transmembrane receptor protein tyrosine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|nervous system development|peripheral nervous system development|cell proliferation|response to wounding|postganglionic parasympathetic nervous system development|neuron differentiation|peristalsis|neuron projection development|positive regulation of monooxygenase activity|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of transcription from RNA polymerase II promoter|mRNA stabilization|enteric nervous system development|enteric nervous system development|sympathetic nervous system development|regulation of dopamine uptake involved in synaptic transmission|ureteric bud formation|regulation of morphogenesis of a branching structure|cellular response to dexamethasone stimulus|regulation of ureteric bud formation|positive regulation of ureteric bud formation|positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,transforming growth factor beta receptor binding|growth factor activity|glial cell line-derived neurotrophic factor receptor binding|protein homodimerization activity|,10,0.7,1.61,10,-0.4,3.84,-0.3,1.59,-1.59,0.553,0,0,-1.5,1.5
ENSMUSG00000017832,HSPB9,"heat shock protein, alpha-crystallin-related, B9",nucleus|cytoplasm|,response to stress|biological_process|,molecular_function|,10,0,0,10,0.3,2.31,0.3,1.58,1.58,0.555,0,0,-0.7,1.6
ENSMUSG00000046032,SNX12,sorting nexin 12,endosome|membrane|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|,lipid binding|phosphatidylinositol binding|,10,-0.1,0.531,10,-0.3,1.38,-0.2,1.56,-1.56,0.558,0,0,-1.6,0.7
ENSMUSG00000057948,UNC13D,unc-13 homolog D (C. elegans),cell|cytoplasm|lysosome|endosome|membrane|exocytic vesicle|,granuloma formation|germinal center formation|exocytosis|phagocytosis|regulation of mast cell degranulation|natural killer cell degranulation|positive regulation of exocytosis|defense response to virus|,protein binding|,10,0,0,10,0.3,2.05,0.2,1.56,1.56,0.558,0,0,-0.8,1.6
ENSMUSG00000040891,FOXA3,forkhead box A3,nucleus|nucleus|,"cellular glucose homeostasis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|spermatogenesis|negative regulation of cell proliferation|cellular response to starvation|chromatin modification|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hepatocyte differentiation|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|protein domain specific binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,-0.2,0.406,10,0.3,2.61,0.3,1.56,1.56,0.558,0,0,-0.9,1.5
ENSMUSG00000014470,RNF166,ring finger protein 166,cellular_component|,biological_process|,zinc ion binding|metal ion binding|,10,0.3,1.67,10,0.1,0.236,0.2,1.52,1.52,0.564,0,0,-0.8,1.6
ENSMUSG00000052133,SEMA5B,"sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B",membrane|integral component of membrane|,multicellular organismal development|nervous system development|cell differentiation|,receptor activity|,10,0.2,0.599,10,0.5,1.7,0.3,1.52,1.52,0.564,0,0,-0.7,1.7
ENSMUSG00000021848,OTX2,orthodenticle homolog 2,nucleus|nucleus|cytoplasm|growth cone|protein complex|,"cell fate specification|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein complex assembly|multicellular organismal development|axon guidance|central nervous system development|endoderm development|organ morphogenesis|anterior/posterior pattern specification|anterior/posterior pattern specification|dorsal/ventral pattern formation|metencephalon development|cell differentiation|neuron differentiation|forebrain development|forebrain development|midbrain development|midbrain development|somite rostral/caudal axis specification|positive regulation of embryonic development|inner ear morphogenesis|eye photoreceptor cell fate commitment|cell fate commitment|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|neuron fate commitment|neuron fate determination|diencephalon morphogenesis|anatomical structure development|primitive streak formation|positive regulation of gastrulation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|protein heterodimerization activity|,10,-0.6,1.47,10,0.5,2.36,-0.5,1.52,-1.52,0.564,0,0,-1.6,1.3
ENSMUSG00000034867,ANKRD27,ankyrin repeat domain 27 (VPS9 domain),cytoplasm|lysosome|early endosome|membrane|,positive regulation of GTPase activity|early endosome to late endosome transport|,guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|,10,-0.2,1.74,10,1,0.866,-0.2,1.51,-1.51,0.565,0,0,-0.8,2
ENSMUSG00000023176,CPN2,"carboxypeptidase N, polypeptide 2",extracellular region|extracellular vesicular exosome|blood microparticle|,biological_process|,molecular_function|,10,-0.2,1.32,10,-0.1,0.475,-0.2,1.51,-1.51,0.565,0,0,-1.4,1.3
ENSMUSG00000042389,TSEN2,tRNA splicing endonuclease 2 homolog (S. cerevisiae),tRNA-intron endonuclease complex|nucleus|cytoplasm|centrosome|,"tRNA splicing, via endonucleolytic cleavage and ligation|mRNA processing|tRNA processing|",tRNA-intron endonuclease activity|nucleic acid binding|nuclease activity|lyase activity|,10,0.8,2.24,10,0.2,0.721,0.3,1.5,1.5,0.567,0,0,-0.8,1.8
ENSMUSG00000020585,LAPTM4A,lysosomal-associated protein transmembrane 4A,Golgi apparatus|plasma membrane|membrane|integral component of membrane|,transport|,None,10,-0.4,1.71,10,-0.1,0.447,-0.2,1.49,-1.49,0.569,0,0,-1.8,0.5
ENSMUSG00000025228,ACTR1A,"ARP1 actin-related protein 1A, centractin alpha",cytoplasm|centrosome|cytoskeleton|extracellular vesicular exosome|,None,nucleotide binding|ATP binding|,10,0.5,2.83,10,0.1,0.0397,0.3,1.49,1.49,0.569,0,0,-0.5,1.8
ENSMUSG00000029788,CPA5,carboxypeptidase A5,cellular_component|extracellular region|,proteolysis|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.5,2.16,10,0.1,0.237,-0.5,1.48,-1.48,0.57,0,0,-1.8,0.6
ENSMUSG00000054422,FABP1,"fatty acid binding protein 1, liver",nucleus|nucleus|cytoplasm|cytoplasm|peroxisomal matrix|cytosol|apical cortex|extracellular vesicular exosome|,transport|long-chain fatty acid transport|positive regulation of fatty acid beta-oxidation|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|intestinal absorption|positive regulation of hydrolase activity|cellular response to hydrogen peroxide|cellular response to hypoxia|,chromatin binding|transporter activity|long-chain fatty acid transporter activity|fatty acid binding|phospholipid binding|drug binding|lipid binding|antioxidant activity|bile acid binding|,10,-0.1,0.795,10,-0.9,2.67,-0.4,1.47,-1.47,0.572,0,0,-1.9,0.5
ENSMUSG00000001020,S100A4,S100 calcium binding protein A4,extracellular space|nucleus|neuron projection|perinuclear region of cytoplasm|extracellular vesicular exosome|,positive regulation of I-kappaB kinase/NF-kappaB signaling|,actin binding|calcium ion binding|calcium ion binding|protein binding|identical protein binding|poly(A) RNA binding|metal ion binding|calcium-dependent protein binding|RAGE receptor binding|,10,0,0,10,0.3,2.21,0.2,1.47,1.47,0.572,0,0,-0.6,1.7
ENSMUSG00000029175,SLC35F6,"solute carrier family 35, member F6",mitochondrion|lysosome|lysosomal membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|positive regulation of cell proliferation|negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|,molecular_function|,10,0.4,1.28,10,0.4,0.303,0.4,1.47,1.47,0.572,0,0,-0.8,1.7
ENSMUSG00000000738,SPG7,spastic paraplegia 7 homolog (human),intracellular|cell|mitochondrion|membrane|integral component of membrane|,proteolysis|mitochondrion organization|cell adhesion|anterograde axon cargo transport|regulation of cell adhesion|,nucleotide binding|metalloendopeptidase activity|ATP binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.3,1.77,10,0.7,3.65,0.2,1.46,1.46,0.574,0,0,-0.8,1.9
ENSMUSG00000073633,FBXO36,F-box protein 36,cellular_component|,biological_process|,molecular_function|,10,-0.3,2.68,10,0,0,-0.3,1.45,-1.45,0.576,0,0,-1.7,0.7
ENSMUSG00000024116,PRSS21,"protease, serine 21",plasma membrane|membrane|anchored component of membrane|,proteolysis|spermatogenesis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.3,1.81,10,0,0,0.3,1.45,1.45,0.576,0,0,-0.4,1.8
ENSMUSG00000037541,SHANK2,SH3/ankyrin domain gene 2,photoreceptor outer segment|photoreceptor inner segment|cytoplasm|neurofilament|plasma membrane|ionotropic glutamate receptor complex|postsynaptic density|membrane|apical plasma membrane|cell junction|growth cone|brush border membrane|cell projection|neuron projection|neuronal cell body|dendritic spine|synapse|postsynaptic membrane|ciliary membrane|,synapse assembly|learning|learning|memory|adult behavior|adult behavior|social behavior|social behavior|exploration behavior|long-term synaptic potentiation|long term synaptic depression|vocalization behavior|vocalization behavior|,protein C-terminus binding|SH3 domain binding|ionotropic glutamate receptor binding|,10,0.4,1.8,10,0,0,0.4,1.43,1.43,0.579,0,0,-0.5,1.8
ENSMUSG00000037437,ADAM32,a disintegrin and metallopeptidase domain 32,cellular_component|membrane|integral component of membrane|,proteolysis|integrin-mediated signaling pathway|,metalloendopeptidase activity|metallopeptidase activity|zinc ion binding|,10,-0.1,0.167,10,-0.5,2.46,-0.3,1.43,-1.43,0.579,0,0,-1.8,0.6
ENSMUSG00000005936,KCTD20,potassium channel tetramerisation domain containing 20,cellular_component|,biological_process|protein homooligomerization|,identical protein binding|,10,0.3,0.703,10,-1.1,1.53,0.2,1.43,1.43,0.579,0,0,-2,1
ENSMUSG00000004069,DNAJA3,"DnaJ (Hsp40) homolog, subfamily A, member 3",nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrial matrix|cytosol|cytosol|actin filament|plasma membrane|IkappaB kinase complex|membrane|extrinsic component of plasma membrane|cell junction|neuromuscular junction|I-kappaB/NF-kappaB complex|mitochondrial nucleoid|intracellular membrane-bounded organelle|synapse|postsynaptic membrane|,negative regulation of transcription from RNA polymerase II promoter|mitochondrial DNA replication|protein folding|negative regulation of protein kinase activity|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation-induced cell death of T cells|mitochondrion organization|small GTPase mediated signal transduction|neuromuscular junction development|neuromuscular junction development|cell aging|negative regulation of cell proliferation|response to heat|embryo development|positive regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB transcription factor activity|T cell differentiation in thymus|response to interferon-gamma|positive regulation of T cell proliferation|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of programmed cell death|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of catalytic activity|protein stabilization|negative regulation of interferon-gamma-mediated signaling pathway|skeletal muscle acetylcholine-gated channel clustering|,small GTPase regulator activity|interferon-gamma receptor binding|protein binding|ATP binding|transcription factor binding|protein kinase binding|Hsp70 protein binding|receptor tyrosine kinase binding|heat shock protein binding|metal ion binding|NF-kappaB binding|unfolded protein binding|,8,0.2,1.02,8,-0.8,1.82,0.2,1.42,1.42,0.58,0,0,-1.8,1.3
ENSMUSG00000053184,SPACA3,sperm acrosome associated 3,acrosomal vesicle|extracellular region|lysosome|membrane|integral component of membrane|secretory granule|cytoplasmic vesicle|,cell wall macromolecule catabolic process|sperm-egg recognition|,lysozyme activity|protein binding|,10,0,0,10,0.6,3.3,0.2,1.42,1.42,0.58,0,0,-0.2,2
ENSMUSG00000034487,KDELC2,KDEL (Lys-Asp-Glu-Leu) containing 2,cellular_component|,biological_process|,molecular_function|,9,0,0,9,0.6,3.68,0.5,1.41,1.41,0.582,0,0,-0.3,2
ENSMUSG00000029822,OSBPL3,oxysterol binding protein-like 3,cytosol|plasma membrane|membrane|nuclear membrane|perinuclear endoplasmic reticulum|,transport|lipid transport|biological_process|,lipid binding|cholesterol binding|,10,-0.1,0.21,10,-0.3,1.75,-0.2,1.4,-1.4,0.584,0,0,-1.9,0.6
ENSMUSG00000005355,CASP14,caspase 14,nucleus|cytoplasm|keratin filament|extracellular vesicular exosome|,proteolysis|proteolysis|apoptotic process|intrinsic apoptotic signaling pathway in response to DNA damage|cell differentiation|extrinsic apoptotic signaling pathway in absence of ligand|,cysteine-type endopeptidase activity|peptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.1,0.224,10,-0.5,2.3,-0.6,1.4,-1.4,0.584,0,0,-1.9,0.7
ENSMUSG00000032724,ABTB2,ankyrin repeat and BTB (POZ) domain containing 2,nucleus|,cellular response to toxic substance|,molecular_function|protein heterodimerization activity|,10,0.1,0.451,10,0.2,1.1,0.2,1.39,1.39,0.585,0,0,-1,1.5
ENSMUSG00000035933,COG5,component of oligomeric golgi complex 5,cytoplasm|Golgi apparatus|membrane|membrane|Golgi transport complex|,transport|intra-Golgi vesicle-mediated transport|protein transport|inter-Golgi cisterna vesicle-mediated transport|,molecular_function|,9,-0.2,1.2,10,0.3,2.16,0.3,1.38,1.38,0.587,0,0,-0.9,1.8
ENSMUSG00000037253,MEX3C,mex3 homolog C (C. elegans),nucleus|cytoplasm|,chondrocyte hypertrophy|regulation of fat cell differentiation|regulation of fat cell differentiation|energy homeostasis|,"RNA binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,1.05,10,-1.1,2.56,-0.3,1.38,-1.38,0.587,0,0,-2,0.2
ENSMUSG00000050896,RTN4RL2,reticulon 4 receptor-like 2,plasma membrane|external side of plasma membrane|cell surface|membrane|anchored component of membrane|membrane raft|anchored component of plasma membrane|extracellular vesicular exosome|,axon regeneration|,receptor activity|,10,-0.2,1.16,10,0.2,0.818,-0.2,1.38,-1.38,0.587,0,0,-1.1,1.6
ENSMUSG00000004934,PIAS4,protein inhibitor of activated STAT 4,intracellular|nucleus|nucleus|cytoplasm|nuclear matrix|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|JAK-STAT cascade|multicellular organismal development|viral process|Wnt signaling pathway|protein sumoylation|protein sumoylation|negative regulation of NF-kappaB transcription factor activity|positive regulation of protein sumoylation|negative regulation of transcription, DNA-templated|positive regulation of keratinocyte apoptotic process|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage|regulation of RNA biosynthetic process|","nucleic acid binding|DNA binding|transcription corepressor activity|transcription corepressor activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|SUMO ligase activity|SUMO ligase activity|ubiquitin protein ligase binding|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,1.73,10,0,0,-0.2,1.38,-1.38,0.587,0,0,-1.5,1.1
ENSMUSG00000014195,DNAJC7,"DnaJ (Hsp40) homolog, subfamily C, member 7",nucleus|cytoplasm|cytoskeleton|membrane|extracellular vesicular exosome|,chaperone cofactor-dependent protein refolding|,heat shock protein binding|,10,0.2,0.571,10,0.3,0.999,0.3,1.38,1.38,0.587,0,0,-0.7,1.7
ENSMUSG00000030161,GABARAPL1,gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1,intracellular|cytoplasm|autophagic vacuole|endoplasmic reticulum|Golgi apparatus|cytoskeleton|microtubule|membrane|cytoplasmic vesicle|dendrite membrane|dendrite cytoplasm|cell body|,autophagy|,protein binding|cytoskeletal protein binding|,10,1,2.65,10,-0.2,0.41,-0.2,1.37,-1.37,0.589,0,0,-0.9,1.9
ENSMUSG00000026365,CFH,complement component factor h,extracellular region|extracellular space|nucleus|cytoplasm|plasma membrane|blood microparticle|,"immune system process|complement activation, alternative pathway|regulation of complement activation|regulation of complement activation|innate immune response|",complement component C3b binding|heparin binding|heparin binding|heparan sulfate proteoglycan binding|,10,-0.1,0.347,10,0.6,3.25,0.5,1.35,1.35,0.592,0,0,-1,1.8
ENSMUSG00000030862,CPXM2,carboxypeptidase X 2 (M14 family),extracellular region|extracellular matrix|,cell adhesion|,metallocarboxypeptidase activity|zinc ion binding|,10,0.5,3.49,10,-0.3,1.41,0.4,1.35,1.35,0.592,0,0,-1.1,1.6
ENSMUSG00000021643,SERF1,small EDRK-rich factor 1,cellular_component|,biological_process|,molecular_function|,4,-0.2,0.472,4,-0.4,1.05,-0.3,1.35,-1.35,0.592,0,0,-2,1.2
ENSMUSG00000007603,DUS3L,dihydrouridine synthase 3-like (S. cerevisiae),cellular_component|,tRNA processing|oxidation-reduction process|,"catalytic activity|oxidoreductase activity|enoyl-[acyl-carrier-protein] reductase activity|tRNA dihydrouridine synthase activity|2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity|cis-2,3-dihydrodiol DDT dehydrogenase activity|trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity|cis-chlorobenzene dihydrodiol dehydrogenase activity|2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity|trans-1,2-dihydrodiolphenanthrene dehydrogenase activity|3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity|benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity|benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity|citronellyl-CoA dehydrogenase activity|menthone dehydrogenase activity|phthalate 3,4-cis-dihydrodiol dehydrogenase activity|cinnamate reductase activity|poly(A) RNA binding|metal ion binding|flavin adenine dinucleotide binding|NADPH-dependent curcumin reductase activity|NADPH-dependent dihydrocurcumin reductase activity|",10,0.2,1.49,10,0.4,0.0985,0.2,1.34,1.34,0.593,0,0,-0.8,1.7
ENSMUSG00000016534,LAMP2,lysosomal-associated membrane protein 2,lysosome|lysosome|lysosomal membrane|lysosomal membrane|endosome|late endosome|late endosome|plasma membrane|membrane|integral component of membrane|phagocytic vesicle membrane|platelet dense granule membrane|late endosome membrane|late endosome membrane|extracellular vesicular exosome|,protein stabilization|,enzyme binding|protein domain specific binding|,9,0.3,1.06,10,0.4,0.493,0.3,1.33,1.33,0.595,0,0,-1.4,1.6
ENSMUSG00000067995,GTF2F2,"general transcription factor IIF, polypeptide 2",nucleus|transcription factor TFIIF complex|microtubule cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",nucleotide binding|DNA binding|catalytic activity|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|,10,0.1,0.193,10,0.9,3.82,0.8,1.31,1.31,0.598,0,0,-0.2,2
ENSMUSG00000073002,VAMP5,vesicle-associated membrane protein 5,intracellular|cell|late endosome|Golgi apparatus|trans-Golgi network|plasma membrane|plasma membrane|integral component of plasma membrane|cell surface|intercalated disc|membrane|integral component of membrane|cytoplasmic vesicle membrane|integral component of organelle membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,multicellular organismal development|muscle organ development|skeletal muscle tissue development|vesicle-mediated transport|cell differentiation|Golgi to plasma membrane protein transport|,None,10,0.5,2.19,10,-0.4,1.66,-0.3,1.31,-1.31,0.598,0,0,-1.3,1.5
ENSMUSG00000064329,SCN1A,"sodium channel, voltage-gated, type I, alpha",voltage-gated sodium channel complex|plasma membrane|intercalated disc|membrane|integral component of membrane|Z disc|T-tubule|axon|node of Ranvier|sodium channel complex|neuronal cell body|axon initial segment|,action potential|transport|ion transport|potassium ion transport|sodium ion transport|adult walking behavior|neuronal action potential propagation|neuronal action potential|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|neuromuscular process controlling posture|potassium ion transmembrane transport|membrane depolarization during action potential|,voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|potassium channel activity|sodium channel activity|sodium ion binding|,10,0.5,3.23,10,0,0,0.3,1.31,1.31,0.598,0,0,-0.9,1.7
ENSMUSG00000018398,8-Sep,septin 8,cytoplasm|cytoskeleton|septin complex|,cell cycle|biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0,0,10,-0.3,2.64,-0.2,1.3,-1.3,0.6,0,0,-1.6,0.8
ENSMUSG00000026740,DNAJC1,"DnaJ (Hsp40) homolog, subfamily C, member 1",nucleus|endoplasmic reticulum|endoplasmic reticulum lumen|plasma membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,regulation of translation|protein folding|regulation of protein secretion|,DNA binding|chromatin binding|protein binding|ribosome binding|chaperone binding|,10,0.1,0.58,10,0.2,0.949,0.2,1.28,1.28,0.603,0,0,-1.1,1.5
ENSMUSG00000028836,SLC30A2,"solute carrier family 30 (zinc transporter), member 2",cytoplasm|lysosomal membrane|late endosome|vacuole|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|,transport|ion transport|cation transport|zinc ion transport|transmembrane transport|positive regulation of sequestering of zinc ion|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|cation transmembrane transporter activity|,10,-0.3,2.64,10,0,0,-0.2,1.27,-1.27,0.605,0,0,-1.7,0.8
ENSMUSG00000031642,SH3RF1,SH3 domain containing ring finger 1,cytoplasm|Golgi apparatus|cytosol|cell projection|,apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of JNK cascade|negative regulation of extrinsic apoptotic signaling pathway|,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.4,2.22,10,-1.1,1.51,0.3,1.27,1.27,0.605,0,0,-2,1.1
ENSMUSG00000004880,LBR,lamin B receptor,nucleus|nuclear envelope|nuclear inner membrane|nuclear pore|nuclear lamina|mitochondrion|membrane|membrane|integral component of membrane|nuclear membrane|,oxidation-reduction process|,"DNA binding|oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor|poly(A) RNA binding|chromo shadow domain binding|",10,0.6,3.81,10,-0.1,0.158,0.6,1.27,1.27,0.605,0,0,-0.5,1.9
ENSMUSG00000029757,DYNC1I1,dynein cytoplasmic 1 intermediate chain 1,"chromosome, centromeric region|kinetochore|spindle pole|chromosome|cytoplasm|cytoskeleton|cytoplasmic dynein complex|microtubule|dynein complex|vesicle|cytoplasmic ribonucleoprotein granule|perinuclear region of cytoplasm|",transport|microtubule-based movement|metabolic process|vesicle transport along microtubule|,motor activity|microtubule motor activity|protein binding|microtubule binding|spectrin binding|,10,-0.1,0.181,10,1,1.4,0.9,1.27,1.27,0.605,0,0,-0.3,2
ENSMUSG00000057457,PHEX,"phosphate regulating endopeptidase homolog, X-linked",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|,proteolysis|organophosphate metabolic process|bone mineralization|biomineral tissue development|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.4,3.43,10,-0.3,1.27,0.3,1.26,1.26,0.607,0,0,-1,1.6
ENSMUSG00000004631,SGCE,"sarcoglycan, epsilon",cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|integral component of plasma membrane|dystrophin-associated glycoprotein complex|sarcoglycan complex|membrane|integral component of membrane|dendrite membrane|cell projection|,None,calcium ion binding|protein binding|,10,-0.3,3.19,10,0.1,0.271,-0.3,1.26,-1.26,0.607,0,0,-1.2,1.8
ENSMUSG00000051648,KCTD19,potassium channel tetramerisation domain containing 19,cellular_component|,biological_process|protein homooligomerization|,molecular_function|,10,0.2,0.322,10,0.3,1.14,0.3,1.26,1.26,0.607,0,0,-0.8,1.7
ENSMUSG00000026269,RNPEPL1,arginyl aminopeptidase (aminopeptidase B)-like 1,cellular_component|,proteolysis|biological_process|,molecular_function|aminopeptidase activity|peptidase activity|hydrolase activity|,10,0.3,3.35,10,0,0,0.3,1.26,1.26,0.607,0,0,-0.7,1.6
ENSMUSG00000044429,CRYGA,"crystallin, gamma A",None,eye development|lens development in camera-type eye|,structural constituent of eye lens|,10,-0.2,1.23,10,-0.1,0.208,-0.2,1.26,-1.26,0.607,0,0,-1.7,0.8
ENSMUSG00000058921,SLC10A5,"solute carrier family 10 (sodium/bile acid cotransporter family), member 5",cellular_component|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|biological_process|,molecular_function|bile acid:sodium symporter activity|symporter activity|,10,0.5,1.78,10,-0.1,0.564,-0.1,1.25,-1.25,0.609,0,0,-1.2,1.6
ENSMUSG00000021200,ASB2,ankyrin repeat and SOCS box-containing 2,Cul5-RING ubiquitin ligase complex|,protein polyubiquitination|intracellular signal transduction|skeletal muscle cell differentiation|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|myoblast differentiation|,ubiquitin-protein transferase activity|,10,-0.2,1.13,10,-0.1,0.306,-0.2,1.25,-1.25,0.609,0,0,-1.6,0.9
ENSMUSG00000029096,HTRA3,HtrA serine peptidase 3,extracellular region|,regulation of cell growth|proteolysis|proteolysis|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|,catalytic activity|endopeptidase activity|serine-type endopeptidase activity|protein binding|insulin-like growth factor binding|peptidase activity|serine-type peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-1,3.6,10,0,0,-0.1,1.25,-1.25,0.609,0,0,-2,0.2
ENSMUSG00000054770,KCTD18,potassium channel tetramerisation domain containing 18,cellular_component|,transport|ion transport|biological_process|,molecular_function|,10,-0.2,1.01,10,-0.3,0.431,-0.3,1.24,-1.24,0.61,0,0,-1.7,0.7
ENSMUSG00000038387,RRAS,"Harvey rat sarcoma oncogene, subgroup R",plasma membrane|membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|negative regulation of cell migration|positive regulation of angiogenesis|,nucleotide binding|GTPase activity|GTP binding|GDP binding|protein complex binding|,10,-0.1,0.172,10,0.3,1.37,0.2,1.24,1.24,0.61,0,0,-1,1.6
ENSMUSG00000024987,CYP26A1,"cytochrome P450, family 26, subfamily a, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,central nervous system development|central nervous system development|anterior/posterior pattern specification|anterior/posterior pattern specification|neural crest cell development|retinoic acid catabolic process|retinoic acid catabolic process|retinoic acid metabolic process|retinoic acid receptor signaling pathway|oxidation-reduction process|,"retinoic acid binding|monooxygenase activity|iron ion binding|retinoic acid 4-hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|fluorene oxygenase activity|mono-butyltin dioxygenase activity|tri-n-butyltin dioxygenase activity|di-n-butyltin dioxygenase activity|methylsilanetriol hydroxylase activity|methyl tertiary butyl ether 3-monooxygenase activity|4-nitrocatechol 4-monooxygenase activity|4-chlorophenoxyacetate monooxygenase activity|tert-butanol 2-monooxygenase activity|alpha-pinene monooxygenase activity|dimethylsilanediol hydroxylase activity|ammonia monooxygenase activity|hydroxymethylsilanetriol oxidase activity|2-hydroxyisobutyrate 3-monooxygenase activity|alpha-pinene dehydrogenase activity|heme binding|bisphenol A hydroxylase B activity|2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity|9-fluorenone-3,4-dioxygenase activity|anthracene 9,10-dioxygenase activity|2-(methylthio)benzothiazole monooxygenase activity|2-hydroxybenzothiazole monooxygenase activity|benzothiazole monooxygenase activity|2,6-dihydroxybenzothiazole monooxygenase activity|pinacolone 5-monooxygenase activity|thioacetamide S-oxygenase activity|thioacetamide S-oxide S-oxygenase activity|endosulfan monooxygenase I activity|N-nitrodimethylamine hydroxylase activity|4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity|endosulfan ether monooxygenase activity|pyrene 4,5-monooxygenase activity|pyrene 1,2-monooxygenase activity|1-hydroxypyrene 6,7-monooxygenase activity|1-hydroxypyrene 7,8-monooxygenase activity|phenylboronic acid monooxygenase activity|spheroidene monooxygenase activity|metal ion binding|",10,0.2,0.317,10,0.2,1.02,0.2,1.24,1.24,0.61,0,0,-0.8,1.6
ENSMUSG00000054469,LCLAT1,lysocardiolipin acyltransferase 1,endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|multicellular organismal development|metabolic process|phospholipid biosynthetic process|,"1-acylglycerol-3-phosphate O-acyltransferase activity|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.3,1.85,10,0.1,0.0752,0.2,1.23,1.23,0.612,0,0,-0.7,1.7
ENSMUSG00000031521,AGA,aspartylglucosaminidase,lysosome|endoplasmic reticulum|extracellular vesicular exosome|,proteolysis|protein deglycosylation|protein maturation|,N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity|N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity|peptidase activity|hydrolase activity|protein self-association|,10,0.3,1.13,10,0.2,0.557,0.3,1.23,1.23,0.612,0,0,-1.1,1.5
ENSMUSG00000025867,CPLX2,complexin 2,cytoplasm|dendrite|SNARE complex|neuronal cell body|synapse|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex|,transport|neurotransmitter transport|exocytosis|nervous system development|synaptic vesicle exocytosis|cell differentiation|positive regulation of synaptic plasticity|mast cell degranulation|,SNARE binding|syntaxin-1 binding|syntaxin binding|calcium-dependent protein binding|,10,-0.4,2.7,10,0.3,1.22,-0.3,1.23,-1.23,0.612,0,0,-1.6,1.1
ENSMUSG00000001558,KLHL10,kelch-like 10,cytoplasm|,cell morphogenesis|spermatogenesis|spermatid development|male gonad development|fertilization|cell differentiation|male genitalia morphogenesis|homeostasis of number of cells within a tissue|,protein binding|,10,0.3,1.6,10,-0.4,1.3,0.2,1.21,1.21,0.616,0,0,-1.6,1.2
ENSMUSG00000063931,PEPD,peptidase D,extracellular vesicular exosome|,proteolysis|collagen catabolic process|,aminopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|dipeptidase activity|manganese ion binding|metal ion binding|,10,0.5,0.392,10,0.2,1.06,0.2,1.21,1.21,0.616,0,0,-1,1.7
ENSMUSG00000028838,EXTL1,exostoses (multiple)-like 1,endoplasmic reticulum|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|,protein glycosylation|,"transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|",10,0.5,1.34,10,0.2,0.395,0.2,1.21,1.21,0.616,0,0,-0.5,1.8
ENSMUSG00000028521,SLC35D1,"solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1",endoplasmic reticulum|membrane|integral component of membrane|,organic anion transport|pyrimidine nucleotide-sugar transport|chondroitin sulfate biosynthetic process|ion transmembrane transport|embryonic skeletal system development|pyrimidine nucleotide-sugar transmembrane transport|,pyrimidine nucleotide-sugar transmembrane transporter activity|,10,-0.1,0.402,10,-0.8,2.31,-0.4,1.21,-1.21,0.616,0,0,-1.9,0.7
ENSMUSG00000026581,SELL,"selectin, lymphocyte",plasma membrane|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|,cell adhesion|response to ATP|regulation of apoptotic process|positive regulation of neutrophil chemotaxis|,protease binding|protein binding|carbohydrate binding|cell adhesion molecule binding|glycolipid binding|,10,0.3,3.22,10,-0.1,0.84,0.3,1.18,1.18,0.621,0,0,-0.8,1.6
ENSMUSG00000031168,EBP,phenylalkylamine Ca2+ antagonist (emopamil) binding protein,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|sterol metabolic process|sterol biosynthetic process|sterol biosynthetic process|hemopoiesis|,C-8 sterol isomerase activity|C-8 sterol isomerase activity|C-8 sterol isomerase activity|isomerase activity|cholestenol delta-isomerase activity|,10,0,0,10,-0.4,2.6,-0.5,1.18,-1.18,0.621,0,0,-1.7,1.4
ENSMUSG00000031780,CCL17,chemokine (C-C motif) ligand 17,extracellular space|,chemotaxis|cellular defense response|signal transduction|cell chemotaxis|,cytokine activity|chemokine activity|CCR4 chemokine receptor binding|,10,0.4,0.806,10,0.8,1.13,0.6,1.18,1.18,0.621,0,0,-1,1.9
ENSMUSG00000027202,SLC12A1,"solute carrier family 12, member 1",plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|extracellular vesicular exosome|,kidney development|transport|ion transport|potassium ion transport|sodium ion transport|chloride transport|excretion|protein insertion into membrane from inner side|ion transmembrane transport|renal rubidium ion absorption|chemical homeostasis|transmembrane transport|chloride transmembrane transport|,transporter activity|protein binding|sodium:potassium:chloride symporter activity|symporter activity|cation:chloride symporter activity|rubidium ion transmembrane transporter activity|,10,0,0,10,-0.3,2.97,-0.2,1.18,-1.18,0.621,0,0,-1.7,0.8
ENSMUSG00000019878,HSF2,heat shock factor 2,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|response to stress|spermatogenesis|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|,10,1.1,4.28,10,-0.4,0.892,1.1,1.17,1.17,0.623,0,0,-1,2
ENSMUSG00000029249,REST,RE1-silencing transcription factor,chromatin|nucleus|nucleus|cytosol|transcriptional repressor complex|transcriptional repressor complex|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of cell proliferation|negative regulation of gene expression|negative regulation of aldosterone biosynthetic process|regulation of ion transmembrane transport|cellular response to drug|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation by host of viral transcription|negative regulation of neuron differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of calcium ion-dependent exocytosis|negative regulation of insulin secretion|negative regulation of neurogenesis|cardiac muscle cell myoblast differentiation|histone H4 deacetylation|cellular response to electrical stimulus|cellular response to glucocorticoid stimulus|potassium ion transmembrane transport|negative regulation of cortisol biosynthetic process|negative regulation of dense core granule biogenesis|negative regulation of mesenchymal stem cell differentiation|negative regulation of amniotic stem cell differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|core promoter sequence-specific DNA binding|core promoter binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|outward rectifier potassium channel activity|protein complex binding|transcription regulatory region DNA binding|metal ion binding|,10,0.2,0.629,10,0.2,0.648,0.2,1.17,1.17,0.623,0,0,-0.8,1.7
ENSMUSG00000067001,SERPINB7,"serine (or cysteine) peptidase inhibitor, clade B, member 7",cellular_component|extracellular space|cytoplasm|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|regulation of proteolysis|positive regulation of transforming growth factor beta1 production|positive regulation of collagen biosynthetic process|positive regulation of glomerular mesangial cell proliferation|positive regulation of platelet-derived growth factor production|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.3,0.776,10,0.7,1.08,0.5,1.17,1.17,0.623,0,0,-0.5,1.9
ENSMUSG00000028954,NUB1,negative regulator of ubiquitin-like proteins 1,nucleus|nucleolus|cytoplasm|,ubiquitin-dependent protein catabolic process|protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|,molecular_function|,10,0.9,0.944,10,0.3,0.674,0.3,1.17,1.17,0.623,0,0,-0.9,1.8
ENSMUSG00000022269,11-Mar,membrane-associated ring finger (C3HC4) 11,cellular_component|membrane|integral component of membrane|cytoplasmic vesicle|,biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.4,1.23,10,0.2,0.305,0.3,1.17,1.17,0.623,0,0,-0.5,1.9
ENSMUSG00000071176,ARHGEF10,Rho guanine nucleotide exchange factor (GEF) 10,centrosome|,myelination in peripheral nervous system|positive regulation of Rho GTPase activity|positive regulation of GTP catabolic process|regulation of Rho protein signal transduction|centrosome duplication|positive regulation of stress fiber assembly|spindle assembly involved in mitosis|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|kinesin binding|,10,-0.2,0.553,10,0.4,2.57,0.3,1.16,1.16,0.624,0,0,-1,1.6
ENSMUSG00000037124,TRIM58,tripartite motif-containing 58,cellular_component|intracellular|,biological_process|,zinc ion binding|metal ion binding|,10,0.4,2.91,10,-0.1,0.093,0.2,1.16,1.16,0.624,0,0,-1.2,1.6
ENSMUSG00000041247,LAMP3,lysosomal-associated membrane protein 3,lysosome|lysosomal membrane|membrane|integral component of membrane|cytoplasmic vesicle|alveolar lamellar body membrane|,immune system process|biological_process|,molecular_function|,10,0.2,0.248,10,0.2,1.01,0.2,1.16,1.16,0.624,0,0,-1.2,1.4
ENSMUSG00000038044,CCT8L1,"chaperonin containing TCP1, subunit 8 (theta)-like 1",cellular_component|cytoplasm|,biological_process|,nucleotide binding|molecular_function|ATP binding|,9,-0.3,2.32,9,0,0,-0.3,1.16,-1.16,0.624,0,0,-1.8,0.8
ENSMUSG00000023987,PGC,progastricsin (pepsinogen C),extracellular region|extracellular vesicular exosome|,proteolysis|digestion|,aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|,10,-0.1,0.14,10,0.3,2.48,0.2,1.14,1.14,0.627,0,0,-1.2,1.4
ENSMUSG00000071553,CPA2,"carboxypeptidase A2, pancreatic",extracellular region|,proteolysis|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.2,1.94,10,0,0,-0.2,1.14,-1.14,0.627,0,0,-1.2,1.6
ENSMUSG00000019590,CYB561,cytochrome b-561,membrane|integral component of membrane|cytoplasmic vesicle|,transport|electron transport chain|oxidation-reduction process|,ferric-chelate reductase activity|transmembrane electron transfer carrier|metal ion binding|,10,0.2,0.905,10,-0.9,3.94,0.2,1.13,1.13,0.629,0,0,-2,0.6
ENSMUSG00000037722,GNPNAT1,glucosamine-phosphate N-acetyltransferase 1,endosome|late endosome|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|,glucosamine metabolic process|N-acetylglucosamine metabolic process|UDP-N-acetylglucosamine biosynthetic process|,"glucosamine 6-phosphate N-acetyltransferase activity|glucosamine 6-phosphate N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|monosaccharide binding|",10,-0.1,0.175,10,-0.2,1.27,-0.2,1.13,-1.13,0.629,0,0,-1.5,1.4
ENSMUSG00000068922,MSTO1,misato homolog 1 (Drosophila),cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|,mitochondrion organization|mitochondrion distribution|,molecular_function|,10,-0.2,0.928,10,1.2,3.31,-0.2,1.12,-1.12,0.631,0,0,-0.6,2
ENSMUSG00000022403,ST13,suppression of tumorigenicity 13,cytoplasm|cytosol|protein complex|extracellular vesicular exosome|,protein folding|protein homooligomerization|negative regulation of protein refolding|chaperone cofactor-dependent protein refolding|,protein domain specific binding|Hsp70 protein binding|protein complex binding|dATP binding|identical protein binding|unfolded protein binding|chaperone binding|,10,0.5,2.19,10,-0.2,1.51,-0.2,1.12,-1.12,0.631,0,0,-1.2,1.6
ENSMUSG00000027184,CAPRIN1,cell cycle associated protein 1,cytoplasmic mRNA processing body|cytoplasm|cytoplasmic stress granule|cytoplasmic stress granule|membrane|cell projection|,negative regulation of translation|cell differentiation|positive regulation of dendrite morphogenesis|positive regulation of dendritic spine morphogenesis|,RNA binding|poly(A) RNA binding|,10,0.2,0.08,10,1.1,3.62,1,1.12,1.12,0.631,0,0,-0.3,2
ENSMUSG00000033486,CATSPER2,"cation channel, sperm associated 2",plasma membrane|cilium|membrane|integral component of membrane|sperm flagellum|CatSper complex|cell projection|,transport|ion transport|calcium ion transport|multicellular organismal development|spermatogenesis|fertilization|cell differentiation|sperm motility|regulation of ion transmembrane transport|sperm capacitation|transmembrane transport|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|calcium activated cation channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|,10,0.4,1.45,10,-0.1,0.156,0.4,1.12,1.12,0.631,0,0,-0.7,1.8
ENSMUSG00000031897,PSMB10,"proteasome (prosome, macropain) subunit, beta type 10",proteasome complex|nucleus|cytoplasm|proteasome core complex|spermatoproteasome complex|,cell morphogenesis|proteolysis|T cell proliferation|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,-0.4,1.73,10,-0.1,0.137,-0.3,1.11,-1.11,0.633,0,0,-1.5,1.4
ENSMUSG00000025170,RAB40B,"Rab40B, member RAS oncogene family",cellular_component|plasma membrane|membrane|,small GTPase mediated signal transduction|protein transport|intracellular signal transduction|,nucleotide binding|GTP binding|,10,0.8,0.907,10,0.2,0.898,0.2,1.09,1.09,0.637,0,0,-0.4,1.9
ENSMUSG00000042607,ASB4,ankyrin repeat and SOCS box-containing 4,Cul2-RING ubiquitin ligase complex|Cul2-RING ubiquitin ligase complex|Cul5-RING ubiquitin ligase complex|Cul5-RING ubiquitin ligase complex|,intracellular signal transduction|protein autoubiquitination|positive regulation of vasculogenesis|,ubiquitin-protein transferase activity|enzyme binding|ubiquitin protein ligase binding|,9,-0.3,0.643,9,-0.2,0.553,-0.2,1.09,-1.09,0.637,0,0,-1.9,0.7
ENSMUSG00000006179,PRSS16,"protease, serine 16 (thymus)",lysosome|lysosome|endosome|endosome|cytoplasmic vesicle|,proteolysis|,peptidase activity|cysteine-type peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,1.76,10,0,0,-0.2,1.08,-1.08,0.639,0,0,-1.6,1
ENSMUSG00000039763,DNAJC28,"DnaJ (Hsp40) homolog, subfamily C, member 28",cellular_component|,biological_process|,molecular_function|,10,0.4,1.89,10,-0.1,0.0604,0.3,1.07,1.07,0.64,0,0,-0.7,1.8
ENSMUSG00000000247,LHX2,LIM homeobox protein 2,intracellular|nucleus|,"neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|nervous system development|axon guidance|brain development|mesoderm development|dorsal/ventral pattern formation|telencephalon development|olfactory bulb development|telencephalon regionalization|telencephalon regionalization|cerebral cortex development|neurogenesis|neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|anatomical structure formation involved in morphogenesis|axon extension|retina development in camera-type eye|negative regulation of transcription regulatory region DNA binding|",RNA polymerase II transcription factor binding transcription factor activity|DNA binding|chromatin binding|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.4,0.74,10,0.8,1.7,-0.3,1.07,-1.07,0.64,0,0,-1.2,1.9
ENSMUSG00000085925,RTL1,retrotransposon-like 1,membrane|integral component of membrane|,multicellular organismal development|,molecular_function|,10,0.7,1.99,10,-0.8,1.36,0.4,1.06,1.06,0.643,0,0,-1.3,1.8
ENSMUSG00000022750,KLHL22,kelch-like 22,cytoplasm|centrosome|polar microtubule|cytoskeleton|Cul3-RING ubiquitin ligase complex|mitotic spindle|,mitotic sister chromatid segregation|protein monoubiquitination|cell cycle|mitotic nuclear division|mitotic spindle assembly checkpoint|cell division|,molecular_function|,10,0.5,2.45,10,-0.1,0.0247,0.2,1.06,1.06,0.643,0,0,-0.7,1.8
ENSMUSG00000038150,ORMDL3,ORM1-like 3 (S. cerevisiae),endoplasmic reticulum|membrane|integral component of membrane|SPOTS complex|,ceramide metabolic process|,molecular_function|,10,-0.2,0.97,10,-0.1,0.343,-0.1,1.06,-1.06,0.643,0,0,-1.3,1.4
ENSMUSG00000041959,S100A10,S100 calcium binding protein A10 (calpactin),endoplasmic reticulum|extrinsic component of plasma membrane|membrane raft|extracellular vesicular exosome|,membrane raft assembly|membrane budding|positive regulation of Rac GTPase activity|positive regulation of binding|protein heterotetramerization|positive regulation of stress fiber assembly|positive regulation of focal adhesion assembly|cellular response to acid|establishment of protein localization to plasma membrane|positive regulation of substrate adhesion-dependent cell spreading|,calcium ion binding|protein binding|protein homodimerization activity|ion channel binding|,10,0.3,0.917,10,0.2,0.34,0.2,1.06,1.06,0.643,0,0,-0.7,1.7
ENSMUSG00000036764,DNAJC12,"DnaJ (Hsp40) homolog, subfamily C, member 12",cellular_component|,biological_process|,None,10,0,0,10,0.3,1.65,0.3,1.04,1.04,0.647,0,0,-0.8,1.7
ENSMUSG00000026308,KLHL30,kelch-like 30,cellular_component|,biological_process|,molecular_function|,10,0.1,0.435,10,0.3,0.791,0.2,1.03,1.03,0.648,0,0,-0.9,1.7
ENSMUSG00000036083,SLC17A3,"solute carrier family 17 (sodium phosphate), member 3",cytoplasm|endoplasmic reticulum membrane|integral component of plasma membrane|apical plasma membrane|perinuclear region of cytoplasm|,drug transmembrane transport|organic anion transport|urate transport|organic acid transport|drug transport|ion transmembrane transport|regulation of ion transmembrane transport|regulation of anion transport|urate metabolic process|toxin transport|,voltage-gated anion channel activity|organic anion transmembrane transporter activity|urate transmembrane transporter activity|drug transmembrane transporter activity|efflux transmembrane transporter activity|toxin transporter activity|,10,-0.4,2.22,10,0,0,-0.2,1.03,-1.03,0.648,0,0,-1.8,0.7
ENSMUSG00000000881,DLG3,"discs, large homolog 3 (Drosophila)",extracellular space|cytoplasm|plasma membrane|cell-cell junction|tight junction|postsynaptic density|growth cone|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|neuronal cell body|dendritic shaft|synapse|,establishment of planar polarity|negative regulation of phosphatase activity|establishment or maintenance of epithelial cell apical/basal polarity|,protein binding|protein C-terminus binding|phosphatase binding|protein phosphatase binding|protein domain specific binding|PDZ domain binding|ubiquitin protein ligase binding|ionotropic glutamate receptor binding|,10,0.2,0.508,10,-0.3,1.47,-0.3,1.03,-1.03,0.648,0,0,-1.5,1.1
ENSMUSG00000042302,EHBP1,EH domain binding protein 1,cytoplasm|membrane|,biological_process|,protein binding|,10,0.6,3.6,10,0,0,0.5,1.02,1.02,0.65,0,0,-0.3,2
ENSMUSG00000031293,RS1,"retinoschisis (X-linked, juvenile) 1 (human)",extracellular region|extrinsic component of plasma membrane|,cell adhesion|retina layer formation|adaptation of rhodopsin mediated signaling|,"phosphatidylserine binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-5-phosphate binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-3,4-bisphosphate binding|phosphatidylinositol-4-phosphate binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0.3,1.52,10,-0.1,0.0306,0.3,1.02,1.02,0.65,0,0,-1.3,1.5
ENSMUSG00000036352,UBAC1,ubiquitin associated domain containing 1,cytoplasm|Golgi apparatus|plasma membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,0.707,10,-0.2,0.422,0.4,1.01,1.01,0.652,0,0,-1.5,1.6
ENSMUSG00000063268,PARP10,"poly (ADP-ribose) polymerase family, member 10",nucleus|cytoplasm|Golgi apparatus|,"protein ADP-ribosylation|negative regulation of gene expression|regulation of chromatin assembly|negative regulation of NF-kappaB transcription factor activity|negative regulation of protein import into nucleus, translocation|negative regulation of viral genome replication|negative regulation of fibroblast proliferation|protein poly-ADP-ribosylation|protein auto-ADP-ribosylation|negative regulation of protein K63-linked ubiquitination|",NAD+ ADP-ribosyltransferase activity|K63-linked polyubiquitin binding|,10,0.1,0.327,10,0.5,1.77,0.3,1,1,0.654,0,0,-0.5,1.9
ENSMUSG00000026200,GLB1L,"galactosidase, beta 1-like",cellular_component|extracellular region|,carbohydrate metabolic process|metabolic process|,"molecular_function|hydrolase activity, hydrolyzing O-glycosyl compounds|beta-galactosidase activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,0.2,0.456,10,-0.6,1.37,0.2,0.998,0.998,0.655,0,0,-1.5,1.4
ENSMUSG00000034799,UNC13A,unc-13 homolog A (C. elegans),cytoplasm|plasma membrane|membrane|cell junction|axon|neuromuscular junction|presynaptic membrane|neuron projection|protein complex|synapse|excitatory synapse|,"positive regulation of neurotransmitter secretion|exocytosis|synaptic transmission|neurotransmitter secretion|neuromuscular junction development|synaptic vesicle docking involved in exocytosis|synaptic vesicle priming|synaptic vesicle maturation|synaptic transmission, glutamatergic|synaptic transmission, glutamatergic|intracellular signal transduction|regulation of short-term neuronal synaptic plasticity|beta-amyloid metabolic process|long-term synaptic potentiation|innervation|",SNARE binding|protein binding|syntaxin-1 binding|protein domain specific binding|diacylglycerol binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|protein N-terminus binding|,10,-0.4,0.481,10,0.2,1.11,0.2,0.994,0.994,0.655,0,0,-1.3,1.5
ENSMUSG00000034391,FBXO15,F-box protein 15,SCF ubiquitin ligase complex|,protein ubiquitination|,ubiquitin-protein transferase activity|protein binding|,10,0.2,1.03,10,0.3,0.0794,0.2,0.993,0.993,0.656,0,0,-0.8,1.7
ENSMUSG00000022091,SORBS3,sorbin and SH3 domain containing 3,nucleus|cytoplasm|cytoskeleton|focal adhesion|focal adhesion|cell junction|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|actin filament organization|cell adhesion|cell-substrate adhesion|positive regulation of MAPK cascade|positive regulation of MAPK cascade|positive regulation of stress fiber assembly|,protein binding|transcription factor binding|vinculin binding|,10,0.2,0.677,10,0.1,0.425,0.2,0.988,0.988,0.657,0,0,-1,1.6
ENSMUSG00000021448,SHC3,src homology 2 domain-containing transforming protein C3,None,"learning or memory|synaptic transmission, glutamatergic|intracellular signal transduction|",protein binding|,10,-0.1,0.0389,10,-0.2,1.13,-0.1,0.986,-0.986,0.657,0,0,-1.8,0.9
ENSMUSG00000032898,FBXO21,F-box protein 21,cellular_component|,biological_process|,molecular_function|DNA binding|,10,0.1,0.863,10,0.2,0.288,0.1,0.982,0.982,0.658,0,0,-0.5,2
ENSMUSG00000044966,FBXO48,F-box protein 48,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.33,10,-0.2,0.0399,-0.3,0.981,-0.981,0.658,0,0,-1.8,0.7
ENSMUSG00000045294,INSIG1,insulin induced gene 1,endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|SREBP-SCAP-Insig complex|,lipid metabolic process|triglyceride metabolic process|cholesterol biosynthetic process|response to sterol depletion|steroid metabolic process|cholesterol metabolic process|negative regulation of steroid biosynthetic process|sterol biosynthetic process|SREBP signaling pathway|inner ear morphogenesis|middle ear morphogenesis|negative regulation of fat cell differentiation|negative regulation of fatty acid biosynthetic process|palate development|cranial suture morphogenesis|negative regulation of cargo loading into COPII-coated vesicle|,protein binding|,10,0.2,0.454,10,0.1,0.611,0.1,0.974,0.974,0.659,0,0,-0.8,1.8
ENSMUSG00000021951,N6AMT2,N-6 adenine-specific DNA methyltransferase 2 (putative),extracellular vesicular exosome|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|nucleic acid binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.3,1.03,10,-0.9,0.426,0.2,0.97,0.97,0.66,0,0,-1.9,1.1
ENSMUSG00000027078,UBE2L6,ubiquitin-conjugating enzyme E2L 6,None,modification-dependent protein catabolic process|ISG15-protein conjugation|,nucleotide binding|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|small conjugating protein ligase activity|ISG15 ligase activity|,10,-0.2,1.21,10,-0.1,0.0922,-0.2,0.968,-0.968,0.66,0,0,-1.7,0.9
ENSMUSG00000089847,TIMM10B,translocase of inner mitochondrial membrane 10B,mitochondrion|mitochondrial inner membrane|membrane|mitochondrial intermembrane space protein transporter complex|,transport|protein transport|,metal ion binding|,10,0,0,10,0.3,2.46,0.2,0.957,0.957,0.663,0,0,-0.8,1.7
ENSMUSG00000001942,SIAE,sialic acid acetylesterase,extracellular space|cytoplasm|lysosome|extracellular vesicular exosome|,regulation of immune system process|carbohydrate metabolic process|,sialate O-acetylesterase activity|hydrolase activity|,10,-0.7,0.181,10,-1,1.42,-0.9,0.945,-0.945,0.665,0,0,-2,0.3
ENSMUSG00000063021,HIST1H2AK,"histone cluster 1, H2ak",nucleosome|nucleus|chromosome|,biological_process|,DNA binding|protein heterodimerization activity|,8,-0.1,0.4,8,-0.4,1.11,-0.2,0.944,-0.944,0.665,0,0,-1.9,0.9
ENSMUSG00000035451,FOXA1,forkhead box A1,nucleus|nucleus|microvillus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|regulation of gene expression|negative regulation of epithelial to mesenchymal transition|chromatin modification|dorsal/ventral neural tube patterning|lung development|response to estradiol|positive regulation of intracellular estrogen receptor signaling pathway|tube morphogenesis|hormone metabolic process|glucose homeostasis|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of smoothened signaling pathway|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|anatomical structure formation involved in morphogenesis|neuron fate specification|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of cell cycle|regulation of cell cycle|epithelial tube branching involved in lung morphogenesis|lung epithelial cell differentiation|secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development|epithelial-mesenchymal signaling involved in prostate gland development|prostate gland epithelium morphogenesis|prostate gland stromal morphogenesis|epithelial cell maturation involved in prostate gland development|connective tissue development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription factor binding|protein domain specific binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0,0,10,0.3,1.4,0.2,0.936,0.936,0.667,0,0,-1.1,1.5
ENSMUSG00000026869,PSMD5,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 5","proteasome regulatory particle, base subcomplex|proteasome accessory complex|",None,protein binding involved in protein folding|,10,-0.2,0.278,10,-0.2,0.736,-0.2,0.933,-0.933,0.667,0,0,-1.7,0.9
ENSMUSG00000025607,COPG2,"coatomer protein complex, subunit gamma 2",cytoplasm|Golgi apparatus|membrane|membrane coat|COPI vesicle coat|cytoplasmic vesicle|,transport|intracellular protein transport|intra-Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,structural molecule activity|,10,0.7,3.25,10,0,0,0.6,0.914,0.914,0.671,0,0,-1.4,1.8
ENSMUSG00000034327,KCTD9,potassium channel tetramerisation domain containing 9,cellular_component|,biological_process|protein homooligomerization|,molecular_function|,10,0.4,2.72,10,-0.3,0.886,-0.3,0.909,-0.909,0.671,0,0,-1.3,1.4
ENSMUSG00000005802,SLC30A4,"solute carrier family 30 (zinc transporter), member 4",cytoplasm|endosome|late endosome|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|,transport|ion transport|cation transport|zinc ion transport|response to toxic substance|zinc ion homeostasis|transmembrane transport|regulation of sequestering of zinc ion|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|cation transmembrane transporter activity|,10,0.2,0.592,10,0.3,0.407,0.2,0.896,0.896,0.674,0,0,-0.7,1.8
ENSMUSG00000031767,NUDT7,nudix (nucleoside diphosphate linked moiety X)-type motif 7,peroxisome|,nucleoside diphosphate metabolic process|coenzyme A catabolic process|acetyl-CoA catabolic process|brown fat cell differentiation|,"magnesium ion binding|RNA binding|acetyl-CoA hydrolase activity|thiamine-pyrophosphatase activity|receptor binding|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|manganese ion binding|snoRNA binding|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|",10,0.1,0.0934,10,-0.3,2.41,-0.2,0.893,-0.893,0.675,0,0,-1.2,1.6
ENSMUSG00000030654,ARL6IP1,ADP-ribosylation factor-like 6 interacting protein 1,cytoplasm|Sec61 translocon complex|cytosol|membrane|membrane|integral component of membrane|,cotranslational protein targeting to membrane|,protein binding|,10,0.3,1.09,10,0.1,0.196,0.2,0.889,0.889,0.675,0,0,-0.8,1.7
ENSMUSG00000075307,KLHL41,kelch-like 41,cytoplasm|cytoplasm|cytoskeleton|pseudopodium|M band|Cul3-RING ubiquitin ligase complex|cell projection|,protein ubiquitination|myofibril assembly|regulation of lateral pseudopodium assembly|skeletal muscle cell differentiation|regulation of myoblast differentiation|regulation of myoblast proliferation|regulation of skeletal muscle cell differentiation|,molecular_function|,10,0.2,1.82,10,0,0,0.2,0.888,0.888,0.676,0,0,-0.5,1.9
ENSMUSG00000048379,SOCS4,suppressor of cytokine signaling 4,cellular_component|,negative regulation of epidermal growth factor-activated receptor activity|negative regulation of signal transduction|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|intracellular signal transduction|regulation of growth|,molecular_function|,10,-0.7,3.74,10,0.2,0.88,-0.7,0.887,-0.887,0.676,0,0,-2,0.6
ENSMUSG00000022517,MGRN1,"mahogunin, ring finger 1",nucleus|cytoplasm|endosome|early endosome|plasma membrane|membrane|membrane|extracellular vesicular exosome|,protein polyubiquitination|protein monoubiquitination|endosome to lysosome transport|negative regulation of cAMP-mediated signaling|negative regulation of G-protein coupled receptor protein signaling pathway|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.371,10,0.2,0.632,0.1,0.885,0.885,0.676,0,0,-0.9,1.7
ENSMUSG00000043943,NAALAD2,N-acetylated alpha-linked acidic dipeptidase 2,membrane|integral component of membrane|,proteolysis|metabolic process|neurotransmitter catabolic process|,catalytic activity|carboxypeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|dipeptidase activity|metal ion binding|N-formylglutamate deformylase activity|,10,0.8,0.744,10,-0.4,3,-0.2,0.878,-0.878,0.678,0,0,-1.3,1.7
ENSMUSG00000047694,YIPF6,"Yip1 domain family, member 6",endoplasmic reticulum|cis-Golgi network|trans-Golgi network|membrane|integral component of membrane|ER to Golgi transport vesicle|,intestinal epithelial cell development|,identical protein binding|,10,0,0,10,0.2,1.68,0.2,0.874,0.874,0.678,0,0,-0.9,1.7
ENSMUSG00000032807,ALOX12B,"arachidonate 12-lipoxygenase, 12R type",cytoplasm|,protein lipidation|lipid metabolic process|fatty acid metabolic process|sphingolipid metabolic process|positive regulation of gene expression|arachidonic acid metabolic process|arachidonic acid metabolic process|lipoxygenase pathway|positive regulation of MAPK cascade|linoleic acid metabolic process|ceramide biosynthetic process|hepoxilin biosynthetic process|oxidation-reduction process|oxidation-reduction process|establishment of skin barrier|positive regulation of mucus secretion|,"arachidonate 12-lipoxygenase activity|arachidonate 12-lipoxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|2,3-dihydroxy DDT 1,2-dioxygenase activity|phenanthrene dioxygenase activity|2,2',3-trihydroxybiphenyl dioxygenase activity|1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity|5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity|1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity|protocatechuate 3,4-dioxygenase type II activity|2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity|3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity|2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity|carbazole 1,9a-dioxygenase activity|dihydroxydibenzothiophene dioxygenase activity|1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity|styrene dioxygenase activity|3,4-dihydroxyphenanthrene dioxygenase activity|hydroquinone 1,2-dioxygenase activity|p-cumate 2,3-dioxygenase activity|2,3-dihydroxy-p-cumate dioxygenase activity|3,5-dichlorocatechol 1,2-dioxygenase activity|2-aminophenol 1,6-dioxygenase activity|2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity|chlorocatechol 1,2-dioxygenase activity|catechol dioxygenase activity|dihydroxyfluorene dioxygenase activity|5-aminosalicylate dioxygenase activity|3-hydroxy-2-naphthoate 2,3-dioxygenase activity|benzo(a)pyrene 11,12-dioxygenase activity|benzo(a)pyrene 4,5-dioxygenase activity|4,5-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 9,10-dioxygenase activity|9,10-dihydroxybenzo(a)pyrene dioxygenase activity|benzo(a)pyrene 7,8-dioxygenase activity|7,8-dihydroxy benzo(a)pyrene dioxygenase activity|1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity|2-mercaptobenzothiazole dioxygenase activity|pyridine-3,4-diol dioxygenase activity|pyrene dioxygenase activity|4,5-dihydroxypyrene dioxygenase activity|phenanthrene-4-carboxylate dioxygenase activity|tetrachlorobenzene dioxygenase activity|4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity|2,3-dihydroxydiphenyl ether dioxygenase activity|diphenyl ether 1,2-dioxygenase activity|arachidonate 8(S)-lipoxygenase activity|metal ion binding|4-hydroxycatechol 1,2-dioxygenase activity|dioxygenase activity|linoleate 9S-lipoxygenase activity|",10,0.1,0.157,10,0.2,0.895,0.2,0.873,0.873,0.679,0,0,-0.7,1.8
ENSMUSG00000029608,RPH3A,rabphilin 3A,Golgi apparatus|cytosol|synaptic vesicle|membrane|extrinsic component of membrane|cell junction|secretory granule|synaptic vesicle membrane|neuron projection|protein complex|synapse|,transport|intracellular protein transport|protein transport|,"transporter activity|calcium ion binding|protein binding|calcium-dependent phospholipid binding|phosphatidylinositol-4,5-bisphosphate binding|zinc ion binding|lipid binding|selenium binding|Rab GTPase binding|protein complex binding|phosphate ion binding|metal ion binding|inositol 1,4,5 trisphosphate binding|",10,-0.1,0.204,10,-0.1,0.74,-0.1,0.869,-0.869,0.68,0,0,-1.8,0.9
ENSMUSG00000004552,CTSE,cathepsin E,endosome|endosome|extracellular vesicular exosome|,proteolysis|protein autoprocessing|antigen processing and presentation of exogenous peptide antigen via MHC class II|antigen processing and presentation of exogenous peptide antigen via MHC class II|,aspartic-type endopeptidase activity|aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|protein homodimerization activity|,10,0.2,0.575,10,-0.9,1.82,0.2,0.869,0.869,0.68,0,0,-2,1
ENSMUSG00000022868,AHSG,alpha-2-HS-glycoprotein,extracellular region|extracellular space|extracellular matrix|protein complex|extracellular vesicular exosome|blood microparticle|,ossification|protein complex assembly|acute-phase response|male gonad development|negative regulation of cell growth|negative regulation of bone mineralization|negative regulation of bone mineralization|positive regulation of bone resorption|negative regulation of insulin receptor signaling pathway|regulation of inflammatory response|positive regulation of phagocytosis|negative regulation of protein tyrosine kinase activity|,cysteine-type endopeptidase inhibitor activity|receptor signaling protein tyrosine kinase inhibitor activity|,10,0.4,1.24,10,0.1,0.0787,0.2,0.864,0.864,0.68,0,0,-0.9,1.7
ENSMUSG00000035898,UBA6,ubiquitin-like modifier activating enzyme 6,cytoplasm|cytosol|,cellular protein modification process|ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|protein ubiquitination|protein ubiquitination|,nucleotide binding|catalytic activity|protein binding|ATP binding|small protein activating enzyme activity|ligase activity|FAT10 activating enzyme activity|FAT10 activating enzyme activity|,9,-0.6,0.143,9,0.5,2.03,0.3,0.86,0.86,0.681,0,0,-1.5,1.6
ENSMUSG00000041180,HECTD2,HECT domain containing 2,nucleus|cytoplasm|,protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.4,3.23,-0.3,0.86,-0.86,0.681,0,0,-2,0.4
ENSMUSG00000041961,ZNRF3,zinc and ring finger 3,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,"ubiquitin-dependent protein catabolic process|Wnt signaling pathway|protein ubiquitination|negative regulation of Wnt signaling pathway|Wnt receptor catabolic process|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|stem cell proliferation|negative regulation of canonical Wnt signaling pathway|negative regulation of non-canonical Wnt signaling pathway|","ubiquitin-protein transferase activity|frizzled binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.558,10,0.1,0.378,0.2,0.853,0.853,0.683,0,0,-0.9,1.7
ENSMUSG00000022684,BFAR,bifunctional apoptosis regulator,endoplasmic reticulum|membrane|integral component of membrane|,apoptotic process|negative regulation of apoptotic process|,molecular_function|zinc ion binding|metal ion binding|,10,0.8,0.195,10,0.3,1.11,0.4,0.847,0.847,0.684,0,0,-0.3,1.9
ENSMUSG00000031591,ASAH1,N-acylsphingosine amidohydrolase 1,lysosome|extracellular vesicular exosome|,lipid metabolic process|response to organic substance|lung development|,hydrolase activity|ceramidase activity|,10,0.4,2.42,10,-0.4,0.683,-0.2,0.847,-0.847,0.684,0,0,-1.2,1.6
ENSMUSG00000047485,KLHL34,kelch-like 34,extracellular space|,biological_process|,molecular_function|,10,0,0,10,0.3,2.22,0.2,0.845,0.845,0.684,0,0,-0.7,1.8
ENSMUSG00000000724,CRYBA1,"crystallin, beta A1",nucleus|cytoplasm|,visual perception|camera-type eye development|,structural constituent of eye lens|protein homodimerization activity|,10,-0.9,0.0629,10,-0.4,2.28,-0.6,0.845,-0.845,0.684,0,0,-1.7,1.5
ENSMUSG00000049291,PRSS38,"protease, serine 38",cellular_component|extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,1.49,10,0,0,-0.2,0.839,-0.839,0.685,0,0,-1.6,1.1
ENSMUSG00000000982,CCL3,chemokine (C-C motif) ligand 3,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|positive regulation of cytosolic calcium ion concentration|regulation of cell shape|neutrophil chemotaxis|leukocyte chemotaxis|positive regulation of tumor necrosis factor production|positive regulation of neuron apoptotic process|astrocyte cell migration|positive regulation of osteoclast differentiation|positive regulation of transcription from RNA polymerase II promoter|macrophage chemotaxis|positive regulation of interleukin-1 beta secretion|positive regulation of inflammatory response|cell chemotaxis|,cytokine activity|protein binding|chemokine activity|chemokine activity|,10,0.3,0.638,10,0.1,0.409,0.2,0.834,0.834,0.686,0,0,-1.1,1.6
ENSMUSG00000002279,LMF1,lipase maturation factor 1,intracellular|cell|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|,ER to Golgi vesicle-mediated transport|protein secretion|protein glycosylation in Golgi|chylomicron remnant clearance|positive regulation of lipoprotein lipase activity|positive regulation of lipoprotein lipase activity|protein maturation|regulation of cholesterol metabolic process|regulation of triglyceride metabolic process|,protein binding|,10,0.3,1.32,10,0.1,0.305,0.2,0.822,0.822,0.689,0,0,-0.7,1.8
ENSMUSG00000050022,AMZ1,archaelysin family metallopeptidase 1,cellular_component|,proteolysis|biological_process|,molecular_function|peptidase activity|cysteine-type peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0,0,10,0.3,2.02,0.2,0.82,0.82,0.689,0,0,-0.8,1.8
ENSMUSG00000040102,KLHL42,kelch-like 42,cytoplasm|cytoskeleton|Cul3-RING ubiquitin ligase complex|,protein polyubiquitination|cell cycle|mitotic nuclear division|regulation of microtubule-based process|proteasome-mediated ubiquitin-dependent protein catabolic process|cell division|,ubiquitin-protein transferase activity|,10,0,0,10,-0.2,1.51,-0.2,0.818,-0.818,0.69,0,0,-1.2,1.9
ENSMUSG00000053565,EIF3K,"eukaryotic translation initiation factor 3, subunit K",nucleus|cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|membrane|extracellular vesicular exosome|,translation|translational initiation|translational initiation|regulation of translational initiation|,RNA binding|translation initiation factor activity|translation initiation factor activity|ribosome binding|,10,0.4,1.14,10,0.1,0.115,0.2,0.806,0.806,0.692,0,0,-1.1,1.6
ENSMUSG00000047246,HIST1H2BE,"histone cluster 1, H2be",extracellular space|nucleus|extracellular vesicular exosome|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,molecular_function|,7,0.5,0.259,6,0.4,0.669,0.5,0.804,0.804,0.693,0,0,-1,2
ENSMUSG00000073888,CCL27A,chemokine (C-C motif) ligand 27A,extracellular region|nucleus|,positive regulation of T cell chemotaxis|positive regulation of mononuclear cell migration|positive regulation of actin cytoskeleton reorganization|,cytokine activity|protein binding|,4,0.1,0.00844,4,0.7,1.86,0.5,0.801,0.801,0.693,0,0,-1.1,2
ENSMUSG00000025432,AVIL,advillin,cytoplasm|cytoskeleton|cell projection|neuron projection|,cytoskeleton organization|actin filament organization|nervous system development|positive regulation of neuron projection development|positive regulation of neuron projection development|actin filament capping|cilium morphogenesis|,actin binding|protein binding|,10,-0.4,2.92,10,0.1,0.523,-0.3,0.789,-0.789,0.696,0,0,-1.8,0.7
ENSMUSG00000010358,IFI35,interferon-induced protein 35,nucleus|,biological_process|,molecular_function|,10,-0.2,0.706,10,0.2,1.49,-0.2,0.788,-0.788,0.696,0,0,-1.4,1.2
ENSMUSG00000050382,KIF7,kinesin family member 7,kinesin complex|microtubule|cilium|cilium|cell projection|,microtubule-based movement|metabolic process|negative regulation of smoothened signaling pathway|positive regulation of smoothened signaling pathway|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|,10,0.2,1.34,10,-0.3,1.11,-0.4,0.783,-0.783,0.697,0,0,-1.5,1.7
ENSMUSG00000038599,CAPN8,calpain 8,intracellular|cytoplasm|Golgi apparatus|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|,10,0.1,0.171,10,0.3,1.14,0.2,0.781,0.781,0.698,0,0,-1,1.7
ENSMUSG00000032307,UBE2Q2,ubiquitin-conjugating enzyme E2Q (putative) 2,cellular_component|cytoplasm|,protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,-0.5,2.06,10,0,0,-0.2,0.781,-0.781,0.698,0,0,-1.9,0.6
ENSMUSG00000024222,FKBP5,FK506 binding protein 5,nucleus|cytoplasm|endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|protein binding|FK506 binding|isomerase activity|,10,0.4,1.9,10,-0.3,0.83,0.2,0.781,0.781,0.698,0,0,-1,1.6
ENSMUSG00000022197,PDZD2,PDZ domain containing 2,extracellular region|nucleus|cytoplasm|endoplasmic reticulum|cell-cell junction|postsynaptic density|cell junction|neuron projection|apical part of cell|,None,None,10,0.3,0.701,10,0.1,0.411,0.1,0.773,0.773,0.699,0,0,-0.7,1.9
ENSMUSG00000045671,SPRED2,"sprouty-related, EVH1 domain containing 2",nucleus|cytoplasm|plasma membrane|membrane|cytoplasmic vesicle|,"inactivation of MAPK activity|multicellular organismal development|regulation of signal transduction|negative regulation of peptidyl-threonine phosphorylation|negative regulation of peptidyl-threonine phosphorylation|positive regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of protein serine/threonine kinase activity|regulation of protein deacetylation|",stem cell factor receptor binding|protein binding|protein kinase binding|protein kinase binding|protein serine/threonine kinase inhibitor activity|,10,0.3,0.724,10,-0.2,0.37,0.4,0.772,0.772,0.699,0,0,-1.2,1.7
ENSMUSG00000036053,FMNL2,formin-like 2,cellular_component|cytoplasm|,cytoskeleton organization|cellular component organization|regulation of cell morphogenesis|actin cytoskeleton organization|cortical actin cytoskeleton organization|,actin binding|Rho GTPase binding|,10,0.2,0.254,10,0.2,0.587,0.2,0.772,0.772,0.699,0,0,-1.2,1.5
ENSMUSG00000029408,ABCB9,"ATP-binding cassette, sub-family B (MDR/TAP), member 9",lysosome|lysosomal membrane|endoplasmic reticulum membrane|membrane|integral component of membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,ATP catabolic process|transport|protein transport|peptide transport|transmembrane transport|transmembrane transport|,"nucleotide binding|ATP binding|peptide transporter activity|peptide-transporting ATPase activity|ATPase activity|substrate-specific transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of substances|protein homodimerization activity|",10,-0.4,1.3,10,-0.1,0.194,-0.2,0.77,-0.77,0.7,0,0,-1.6,1.5
ENSMUSG00000039372,4-Mar,membrane-associated ring finger (C3HC4) 4,Golgi apparatus|Golgi stack|trans-Golgi network|membrane|integral component of membrane|,protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.0586,10,0.2,0.873,0.2,0.764,0.764,0.701,0,0,-0.9,1.7
ENSMUSG00000036748,CUEDC2,CUE domain containing 2,nucleus|cytoplasm|nuclear membrane|,biological_process|,molecular_function|,10,0.3,1.79,10,0,0,0.2,0.753,0.753,0.703,0,0,-1,1.6
ENSMUSG00000041225,ARHGAP12,Rho GTPase activating protein 12,intracellular|,morphogenesis of an epithelial sheet|signal transduction|,molecular_function|GTPase activator activity|,10,-0.3,0.419,10,-0.1,0.435,-0.2,0.747,-0.747,0.705,0,0,-1.8,0.8
ENSMUSG00000024787,SNX15,sorting nexin 15,nucleolus|cytoplasm|membrane|cytoplasmic vesicle|,transport|biological_process|protein transport|,molecular_function|lipid binding|phosphatidylinositol binding|,10,0.4,1.13,10,-0.1,0.332,-0.1,0.741,-0.741,0.706,0,0,-1.2,1.5
ENSMUSG00000028189,CTBS,"chitobiase, di-N-acetyl-",extracellular space|lysosome|extracellular vesicular exosome|,carbohydrate metabolic process|chitin catabolic process|metabolic process|oligosaccharide catabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|chitinase activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,-0.3,0.957,10,-0.1,0.0905,-0.2,0.741,-0.741,0.706,0,0,-1.9,0.7
ENSMUSG00000031171,FTSJ1,FtsJ homolog 1 (E. coli),cellular_component|,biological_process|,molecular_function|,10,0.3,0.516,10,0.2,0.628,0.3,0.74,0.74,0.706,0,0,-1.2,1.7
ENSMUSG00000030055,RAB43,"RAB43, member RAS oncogene family",Golgi apparatus|membrane|cytoplasmic vesicle|phagocytic vesicle|extracellular vesicular exosome|,"GTP catabolic process|Golgi organization|small GTPase mediated signal transduction|protein transport|retrograde transport, plasma membrane to Golgi|phagosome maturation|",nucleotide binding|GTPase activity|GTP binding|,10,0.3,1.21,10,0,0,0.2,0.733,0.733,0.707,0,0,-1.1,1.6
ENSMUSG00000009588,ST6GALNAC1,"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1",Golgi apparatus|membrane|integral component of membrane|,ganglioside biosynthetic process|protein glycosylation|oligosaccharide biosynthetic process|sialylation|,"alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity|sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.1,0.1,10,0.2,1.06,0.2,0.73,0.73,0.708,0,0,-1.1,1.6
ENSMUSG00000045867,CRADD,CASP2 and RIPK1 domain containing adaptor with death domain,intracellular|nucleus|cytoplasm|,"apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|signal transduction|regulation of apoptotic process|positive regulation of apoptotic signaling pathway|","protease binding|protein binding, bridging|death domain binding|",10,0.3,1.58,10,-0.1,0.319,0.2,0.72,0.72,0.711,0,0,-1.7,1.1
ENSMUSG00000020905,USP43,ubiquitin specific peptidase 43,cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,-0.2,0.938,10,-0.1,0.0668,-0.2,0.717,-0.717,0.711,0,0,-1.5,1.2
ENSMUSG00000036620,MGAT4B,"mannoside acetylglucosaminyltransferase 4, isoenzyme B",cellular_component|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|biological_process|,"molecular_function|alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|metal ion binding|",10,0.2,0.782,10,0.1,0.111,0.2,0.714,0.714,0.712,0,0,-1.1,1.6
ENSMUSG00000023073,SLC10A2,"solute carrier family 10, member 2",proteasome complex|nucleus|microvillus|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|,transport|ion transport|sodium ion transport|lipid transport|organic anion transport|bile acid and bile salt transport|sodium ion transmembrane transport|,bile acid:sodium symporter activity|symporter activity|,10,0,0,10,-0.3,1.71,-0.2,0.711,-0.711,0.712,0,0,-1.6,1
ENSMUSG00000031782,COQ9,coenzyme Q9 homolog (yeast),mitochondrion|mitochondrion|,"mitochondrial electron transport, NADH to ubiquinone|ubiquinone biosynthetic process|",molecular_function|,10,0,0,10,0.3,1.07,0.2,0.706,0.706,0.713,0,0,-1.6,1.4
ENSMUSG00000038009,DNAJC22,"DnaJ (Hsp40) homolog, subfamily C, member 22",cellular_component|membrane|integral component of membrane|,biological_process|,None,10,0.2,0.419,10,0.2,0.349,0.2,0.704,0.704,0.714,0,0,-0.8,1.8
ENSMUSG00000035840,LYSMD3,"LysM, putative peptidoglycan-binding, domain containing 3",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.2,0.568,10,0.1,0.237,0.2,0.699,0.699,0.715,0,0,-0.9,1.8
ENSMUSG00000030720,CLN3,"ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)",Golgi membrane|intracellular|cell|nucleus|cytoplasm|lysosome|lysosome|lysosomal membrane|endosome|early endosome|early endosome|late endosome|late endosome|autophagic vacuole|endoplasmic reticulum|Golgi apparatus|Golgi stack|trans-Golgi network|plasma membrane|caveola|synaptic vesicle|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|integral component of organelle membrane|cytoplasmic vesicle|neuron projection|lysosomal lumen|membrane raft|,autophagic vacuole fusion|action potential|globoside metabolic process|cellular amino acid metabolic process|ceramide metabolic process|glucosylceramide metabolic process|galactosylceramide metabolic process|sphingomyelin metabolic process|transport|amino acid transport|receptor-mediated endocytosis|vacuolar transport|lysosome organization|lysosomal lumen acidification|lysosomal lumen acidification|associative learning|regulation of gene expression|arginine transport|arginine transport|macroautophagy|negative regulation of macroautophagy|protein processing|ionotropic glutamate receptor signaling pathway|lysosomal lumen pH elevation|neurotransmitter metabolic process|amyloid precursor protein catabolic process|negative regulation of apoptotic process|negative regulation of catalytic activity|negative regulation of neuron apoptotic process|negative regulation of proteolysis|vesicle transport along microtubule|neuromuscular process controlling balance|cytosolic calcium ion homeostasis|membrane organization|,protein binding|calcium-dependent protein binding|,10,-0.5,2.74,10,0,0,-0.4,0.698,-0.698,0.715,0,0,-1.8,1
ENSMUSG00000062488,I830012O16RIK,RIKEN cDNA I830012O16 gene,cytoplasm|mitochondrion|,biological_process|,identical protein binding|,10,0.1,0.58,10,0.9,1.63,0.2,0.697,0.697,0.715,0,0,-0.4,2
ENSMUSG00000051209,GPR119,G-protein coupled receptor 119,cell|plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|insulin secretion|,signal transducer activity|G-protein coupled receptor activity|lipid binding|phosphatidylcholine binding|,10,-0.1,0.28,10,-0.4,0.52,-0.1,0.69,-0.69,0.717,0,0,-1.8,0.8
ENSMUSG00000035540,GC,group specific component,extracellular region|extracellular space|cytosol|axon|perinuclear region of cytoplasm|extracellular vesicular exosome|blood microparticle|,transport|vitamin D metabolic process|vitamin transport|,actin binding|vitamin D binding|vitamin transporter activity|calcidiol binding|,10,-0.2,1.24,10,0.3,1.42,-0.2,0.689,-0.689,0.717,0,0,-1.4,1.3
ENSMUSG00000027606,DNAJC5B,"DnaJ (Hsp40) homolog, subfamily C, member 5 beta",cellular_component|membrane|,biological_process|,None,10,0,0,10,-0.2,1.2,-0.2,0.688,-0.688,0.717,0,0,-1.9,0.8
ENSMUSG00000021922,ITIH4,"inter alpha-trypsin inhibitor, heavy chain 4",extracellular region|cytoplasm|plasma membrane|extracellular vesicular exosome|blood microparticle|,acute-phase response|negative regulation of peptidase activity|hyaluronan metabolic process|,serine-type endopeptidase inhibitor activity|protein binding|peptidase inhibitor activity|,10,-0.2,0.708,10,0.1,0.264,0.2,0.686,0.686,0.718,0,0,-1.1,1.6
ENSMUSG00000019874,FABP7,"fatty acid binding protein 7, brain",nucleus|cytoplasm|cytosol|cell projection|neuronal cell body|cell body|,startle response|transport|cell proliferation in forebrain|neurogenesis|epithelial cell proliferation|prepulse inhibition|,transporter activity|fatty acid binding|lipid binding|,10,-0.6,0.55,10,0.3,0.802,0.2,0.684,0.684,0.718,0,0,-1.6,1.2
ENSMUSG00000027482,BPIFA3,"BPI fold containing family A, member 3",cellular_component|extracellular region|,biological_process|,lipid binding|,10,0.3,0.723,10,0.1,0.206,0.1,0.677,0.677,0.72,0,0,-1.6,1.4
ENSMUSG00000042672,DCST1,DC-STAMP domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|metal ion binding|,10,0.5,2.95,10,-0.4,1.07,0.4,0.676,0.676,0.72,0,0,-1.1,1.6
ENSMUSG00000015016,ACSF3,acyl-CoA synthetase family member 3,mitochondrion|mitochondrion|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|metabolic process|malonate catabolic process|,"nucleotide binding|catalytic activity|acyl-CoA ligase activity|succinate-CoA ligase activity|ATP binding|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity|fatty acid ligase activity|ligase activity|acid-thiol ligase activity|3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity|benzoyl acetate-CoA ligase activity|2,4-dichlorobenzoate-CoA ligase activity|pivalate-CoA ligase activity|cyclopropanecarboxylate-CoA ligase activity|adipate-CoA ligase activity|citronellyl-CoA ligase activity|mentha-1,3-dione-CoA ligase activity|thiophene-2-carboxylate-CoA ligase activity|2,4,4-trimethylpentanoate-CoA ligase activity|cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity|3-hydroxypropionyl-CoA synthetase activity|perillic acid:CoA ligase (ADP-forming) activity|perillic acid:CoA ligase (AMP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity|pristanate-CoA ligase activity|malonyl-CoA synthetase activity|",10,-0.2,1.38,10,0.2,1.05,-0.1,0.671,-0.671,0.721,0,0,-0.9,1.8
ENSMUSG00000043716,RPL7,ribosomal protein L7,nucleus|ribosome|membrane|cytosolic large ribosomal subunit|cytosolic large ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,rRNA processing|translation|ribosomal large subunit biogenesis|,DNA binding|RNA binding|mRNA binding|structural constituent of ribosome|protein homodimerization activity|poly(A) RNA binding|,8,0.2,0.55,8,0.1,0.265,0.1,0.671,0.671,0.721,0,0,-1.3,1.7
ENSMUSG00000021252,0610007P14RIK,RIKEN cDNA 0610007P14 gene,endoplasmic reticulum|membrane|integral component of membrane|transport vesicle|,lipid metabolic process|steroid biosynthetic process|steroid metabolic process|sterol biosynthetic process|,None,10,0.9,2.66,10,-0.2,0.265,-0.1,0.67,-0.67,0.721,0,0,-0.7,2
ENSMUSG00000003316,GLG1,golgi apparatus protein 1,Golgi membrane|Golgi apparatus|Golgi apparatus|Golgi medial cisterna|plasma membrane|membrane|membrane|integral component of membrane|extracellular matrix|intracellular membrane-bounded organelle|extracellular vesicular exosome|,negative regulation of protein processing|negative regulation of protein processing|negative regulation of transforming growth factor beta receptor signaling pathway|regulation of chondrocyte differentiation|bone morphogenesis|,fibroblast growth factor binding|,10,0.2,0.93,10,0.1,0.103,0.1,0.668,0.668,0.722,0,0,-1,1.7
ENSMUSG00000021221,DPF3,"D4, zinc and double PHD fingers, family 3",nucleus|nBAF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|chromatin modification|",zinc ion binding|metal ion binding|,10,-0.4,2.03,10,0.4,1.73,-0.2,0.667,-0.667,0.722,0,0,-1.5,1.3
ENSMUSG00000048236,OVCH2,ovochymase 2,cellular_component|extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|metal ion binding|,10,0,0,10,0.4,1.75,0.3,0.664,0.664,0.723,0,0,-0.9,1.8
ENSMUSG00000030162,OLR1,oxidized low density lipoprotein (lectin-like) receptor 1,extracellular region|nucleus|plasma membrane|membrane|integral component of membrane|extrinsic component of plasma membrane|intracellular membrane-bounded organelle|receptor complex|extracellular vesicular exosome|,immune system process|receptor-mediated endocytosis|inflammatory response|cell adhesion|leukocyte cell-cell adhesion|cell death|lipoprotein metabolic process|,low-density lipoprotein receptor activity|carbohydrate binding|,10,0.2,0.477,10,0.2,0.243,0.2,0.66,0.66,0.724,0,0,-0.9,1.8
ENSMUSG00000018927,CCL6,chemokine (C-C motif) ligand 6,extracellular region|extracellular space|,chemotaxis|immune response|cell chemotaxis|,cytokine activity|chemokine activity|,10,0.2,0.92,10,0,0,0.1,0.66,0.66,0.724,0,0,-0.9,1.8
ENSMUSG00000024048,MYL12A,"myosin, light chain 12A, regulatory, non-sarcomeric",stress fiber|intracellular|cell|myosin II complex|Z disc|protein complex|extracellular vesicular exosome|,regulation of cell shape|protein targeting to plasma membrane|,protein binding|glutamate receptor binding|,8,-1,2.23,8,-0.1,0.0254,-0.1,0.659,-0.659,0.724,0,0,-2,0.8
ENSMUSG00000071655,UBXN1,UBX domain protein 1,proteasome complex|nucleus|cytoplasm|dendrite|Cdc48p-Npl4p-Ufd1p AAA ATPase complex|neuronal cell body|,negative regulation of protein ubiquitination|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|,polyubiquitin binding|ubiquitin protein ligase binding|ubiquitin binding|ATPase binding|K6-linked polyubiquitin binding|,10,-0.8,1.12,10,-0.1,0.107,-0.1,0.655,-0.655,0.725,0,0,-2,0.6
ENSMUSG00000024610,CD74,"CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)",intracellular|lysosome|late endosome|multivesicular body|vacuole|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|macrophage migration inhibitory factor receptor complex|macrophage migration inhibitory factor receptor complex|NOS2-CD74 complex|MHC class II protein complex|extracellular vesicular exosome|,"activation of MAPK activity|prostaglandin biosynthetic process|positive regulation of cytokine-mediated signaling pathway|positive regulation of cytokine-mediated signaling pathway|immune system process|positive regulation of dendritic cell antigen processing and presentation|negative regulation of peptide secretion|positive regulation of adaptive immune response|positive regulation of type 2 immune response|negative regulation of mature B cell apoptotic process|protein folding|protein complex assembly|intracellular protein transport|intracellular protein transport|defense response|immune response|signal transduction|cell proliferation|immunoglobulin mediated immune response|cytokine-mediated signaling pathway|antigen processing and presentation|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|positive regulation of B cell proliferation|macrophage migration inhibitory factor signaling pathway|negative regulation of apoptotic process|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of DNA damage response, signal transduction by p53 class mediator|positive thymic T cell selection|negative thymic T cell selection|positive regulation of innate immune response|negative regulation of T cell differentiation|positive regulation of T cell differentiation|positive regulation of fibroblast proliferation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|chaperone mediated protein folding requiring cofactor|chaperone mediated protein folding requiring cofactor|positive regulation of macrophage cytokine production|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of neutrophil chemotaxis|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of chemokine (C-X-C motif) ligand 2 production|","beta-amyloid binding|cytokine receptor activity|cytokine receptor activity|protein binding|cytokine binding|cytokine binding|MHC class II protein complex binding|macrophage migration inhibitory factor binding|MHC class II protein binding|MHC class II protein binding, via antigen binding groove|protein binding involved in protein folding|nitric-oxide synthase binding|",10,-0.3,1.24,10,0,0,-0.2,0.645,-0.645,0.727,0,0,-1.8,0.8
ENSMUSG00000060441,TRIM5,tripartite motif-containing 5,cytoplasmic mRNA processing body|nucleus|cytoplasm|Golgi apparatus|,pattern recognition receptor signaling pathway|protein ubiquitination|,ubiquitin-protein transferase activity|signaling pattern recognition receptor activity|identical protein binding|protein homodimerization activity|metal ion binding|,10,-0.2,0.977,10,0,0,-0.2,0.638,-0.638,0.729,0,0,-1.3,1.5
ENSMUSG00000031552,ADAM18,a disintegrin and metallopeptidase domain 18,cellular_component|membrane|integral component of membrane|,proteolysis|integrin-mediated signaling pathway|multicellular organismal development|spermatogenesis|cell differentiation|,metalloendopeptidase activity|integrin binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|,9,0.2,0.768,9,0.1,0.152,0.2,0.637,0.637,0.729,0,0,-1.7,1.2
ENSMUSG00000021906,OXNAD1,oxidoreductase NAD-binding domain containing 1,mitochondrion|,oxidation-reduction process|,N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,-0.2,0.946,10,0.7,1.04,-0.1,0.634,-0.634,0.73,0,0,-0.9,2
ENSMUSG00000049929,LPAR4,lysophosphatidic acid receptor 4,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|lipid binding|,10,-0.3,1.53,10,0,0,-0.1,0.633,-0.633,0.73,0,0,-1.8,0.9
ENSMUSG00000004849,AP1S1,"adaptor protein complex AP-1, sigma 1",Golgi apparatus|trans-Golgi network|coated pit|membrane|membrane|membrane coat|AP-1 adaptor complex|cytoplasmic vesicle|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|vesicle-mediated transport|,protein binding|protein transporter activity|,10,1.4,0.78,10,0.1,0.0778,0.1,0.632,0.632,0.73,0,0,-0.6,2
ENSMUSG00000003464,PEX19,peroxisomal biogenesis factor 19,nucleus|cytoplasm|peroxisome|peroxisomal membrane|cytosol|membrane|integral component of membrane|brush border membrane|intracellular membrane-bounded organelle|protein complex|,protein targeting to peroxisome|peroxisome organization|peroxisome membrane biogenesis|peroxisome fission|protein import into peroxisome membrane|protein stabilization|chaperone-mediated protein folding|chaperone-mediated protein transport|establishment of protein localization to peroxisome|negative regulation of lipid binding|,protein binding|peroxisome membrane class-1 targeting sequence binding|protein N-terminus binding|ATPase binding|,10,0.1,0.673,10,0.4,0.35,0.1,0.627,0.627,0.731,0,0,-0.5,2
ENSMUSG00000047013,FBXO41,F-box protein 41,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.457,10,-0.1,0.289,-0.1,0.625,-0.625,0.732,0,0,-1.2,1.5
ENSMUSG00000043415,OTUD1,OTU domain containing 1,cellular_component|,proteolysis|protein K63-linked deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,-0.1,0.0796,10,-0.2,0.705,-0.2,0.625,-0.625,0.732,0,0,-1.7,1.1
ENSMUSG00000027957,SLC35A3,"solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3",Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,transport|carbohydrate transport|nucleotide-sugar transport|UDP-N-acetylglucosamine transport|,nucleotide-sugar transmembrane transporter activity|sugar:proton symporter activity|,10,0,0,10,-0.3,2.02,-0.2,0.619,-0.619,0.733,0,0,-1.9,0.7
ENSMUSG00000013418,B4GALNT2,"beta-1,4-N-acetyl-galactosaminyl transferase 2",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,UDP-N-acetylglucosamine metabolic process|protein glycosylation|UDP-N-acetylgalactosamine metabolic process|UDP-N-acetylgalactosamine metabolic process|negative regulation of cell-cell adhesion|negative regulation of cell-cell adhesion|lipid glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.5,1.22,10,0.5,1.53,0.1,0.616,0.616,0.734,0,0,-1.5,1.5
ENSMUSG00000024773,ATG2A,autophagy related 2A,pre-autophagosomal structure|lipid particle|membrane|extrinsic component of membrane|,autophagic vacuole assembly|mitochondrion degradation|autophagy|cellular response to nitrogen starvation|nucleophagy|,molecular_function|,10,0.3,1.01,10,-0.2,0.646,0.1,0.602,0.602,0.737,0,0,-1.5,1.4
ENSMUSG00000041911,DLX1,distal-less homeobox 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|proximal/distal pattern formation|proximal/distal pattern formation|subpallium development|hippocampus development|forebrain neuron differentiation|regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment|cerebral cortex GABAergic interneuron differentiation|cerebral cortex GABAergic interneuron fate commitment|cell differentiation|odontogenesis of dentin-containing tooth|negative regulation of neuron apoptotic process|negative regulation of Notch signaling pathway|embryonic skeletal system development|embryonic skeletal system development|negative regulation of oligodendrocyte differentiation|",DNA binding|chromatin binding|sequence-specific DNA binding|,10,0.2,0.354,10,0.1,0.402,0.1,0.599,0.599,0.738,0,0,-0.7,1.9
ENSMUSG00000005202,SHBG,sex hormone binding globulin,extracellular region|extracellular vesicular exosome|,primary spermatocyte growth|,steroid binding|lipid binding|,10,0.3,1.1,10,0.1,0.00539,0.2,0.598,0.598,0.738,0,0,-0.8,1.8
ENSMUSG00000046836,BROX,BRO1 domain and CAAX motif containing,membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.2,0.379,10,0.4,0.319,0.3,0.592,0.592,0.739,0,0,-1.1,1.7
ENSMUSG00000095463,ENTPD4,ectonucleoside triphosphate diphosphohydrolase 4,integral component of Golgi membrane|intracellular membrane-bounded organelle|,UDP catabolic process|,uridine-diphosphatase activity|,10,-0.2,0.876,10,0.1,0.0499,-0.2,0.589,-0.589,0.74,0,0,-1.6,1.2
ENSMUSG00000000627,SEMA4F,"sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain",endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|synapse|postsynaptic membrane|,multicellular organismal development|nervous system development|axon guidance|cell differentiation|negative regulation of axon extension|retinal ganglion cell axon guidance|,receptor activity|protein binding|,10,0.1,0.22,10,-0.2,0.744,-0.1,0.581,-0.581,0.741,0,0,-1.2,1.4
ENSMUSG00000027375,MAL,"myelin and lymphocyte protein, T cell differentiation protein",endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|extrinsic component of membrane|membrane raft|,myelination|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|,structural constituent of myelin sheath|,10,0.1,0.0751,10,-0.2,1.61,-0.1,0.575,-0.575,0.743,0,0,-1.5,1.2
ENSMUSG00000025789,ST8SIA2,"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2",early endosome|Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|recycling endosome|,ganglioside biosynthetic process|protein glycosylation|N-glycan processing|oligosaccharide metabolic process|sialylation|sialylation|,"alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.1,0.0583,10,0.2,0.708,0.1,0.572,0.572,0.743,0,0,-0.9,1.8
ENSMUSG00000029998,PCYOX1,prenylcysteine oxidase 1,lysosome|plasma membrane|very-low-density lipoprotein particle|extracellular vesicular exosome|,ATP catabolic process|chloride transport|prenylated protein catabolic process|prenylcysteine catabolic process|oxidation-reduction process|chloride transmembrane transport|,"prenylcysteine oxidase activity|prenylcysteine oxidase activity|chloride-transporting ATPase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor|",10,0.3,1.03,10,0.1,0.0503,0.1,0.568,0.568,0.744,0,0,-1.3,1.6
ENSMUSG00000058183,MMEL1,membrane metallo-endopeptidase-like 1,extracellular region|extracellular space|extracellular space|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,proteolysis|,metalloendopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.5,1.97,10,0.3,0.899,-0.4,0.567,-0.567,0.745,0,0,-1.8,1
ENSMUSG00000031640,KLKB1,"kallikrein B, plasma 1",extracellular region|extracellular space|,proteolysis|inflammatory response|blood coagulation|hemostasis|plasminogen activation|fibrinolysis|positive regulation of fibrinolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.39,10,0.1,0.227,0.1,0.565,0.565,0.745,0,0,-1,1.8
ENSMUSG00000005493,MSH4,mutS homolog 4 (E. coli),condensed chromosome|condensed nuclear chromosome|synaptonemal complex|synaptonemal complex|nucleus|,ovarian follicle development|ATP catabolic process|mismatch repair|meiotic nuclear division|meiotic nuclear division|synapsis|reciprocal meiotic recombination|spermatogenesis|female gamete generation|homologous chromosome segregation|chiasma assembly|,nucleotide binding|DNA binding|ATP binding|DNA-dependent ATPase activity|mismatched DNA binding|,10,-0.2,0.561,10,-0.1,0.099,-0.1,0.563,-0.563,0.746,0,0,-1.6,1.2
ENSMUSG00000047149,OLFR1052,olfactory receptor 1052,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,0.416,10,-0.2,0.554,-0.4,0.56,-0.56,0.746,0,0,-1.9,0.7
ENSMUSG00000058586,SERHL,serine hydrolase-like,cytoplasm|mitochondrion|peroxisome|cytoplasmic membrane-bounded vesicle|,None,nuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,-0.3,1.14,10,0,0,-0.2,0.555,-0.555,0.748,0,0,-1.4,1.4
ENSMUSG00000026958,DPP7,dipeptidylpeptidase 7,extracellular region|lysosome|cytosol|cytoplasmic vesicle|extracellular vesicular exosome|,proteolysis|,aminopeptidase activity|peptidase activity|serine-type peptidase activity|dipeptidyl-peptidase activity|hydrolase activity|,10,-0.2,0.504,10,1.2,0.711,-0.1,0.553,-0.553,0.748,0,0,-1.1,2
ENSMUSG00000053510,NRD1,"nardilysin, N-arginine dibasic convertase, NRD convertase 1",mitochondrion|,proteolysis|positive regulation of membrane protein ectodomain proteolysis|regulation of endopeptidase activity|,catalytic activity|metalloendopeptidase activity|protein binding|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.2,0.45,10,0.1,0.241,0.1,0.548,0.548,0.749,0,0,-0.9,1.8
ENSMUSG00000026188,TMEM169,transmembrane protein 169,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.105,10,-0.2,0.563,-0.2,0.544,-0.544,0.75,0,0,-1.1,1.9
ENSMUSG00000000876,PXMP4,peroxisomal membrane protein 4,peroxisome|peroxisomal membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.51,10,-0.1,0.0529,0.3,0.542,0.542,0.751,0,0,-1,1.8
ENSMUSG00000037071,SCD1,stearoyl-Coenzyme A desaturase 1,endoplasmic reticulum|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|positive regulation of cholesterol esterification|cholesterol esterification|negative regulation of growth of symbiont in host|defense response to Gram-positive bacterium|white fat cell differentiation|brown fat cell differentiation|oxidation-reduction process|,"stearoyl-CoA 9-desaturase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water|",9,-0.6,1.45,10,1,1.12,-0.5,0.539,-0.539,0.752,0,0,-1.4,1.9
ENSMUSG00000043881,KBTBD7,kelch repeat and BTB (POZ) domain containing 7,cellular_component|,biological_process|,molecular_function|,10,0.2,0.432,10,0.1,0.239,0.1,0.539,0.539,0.752,0,0,-1.3,1.5
ENSMUSG00000050017,PITPNB,"phosphatidylinositol transfer protein, beta",intracellular|cytoplasm|Golgi apparatus|extracellular vesicular exosome|,in utero embryonic development|transport|phospholipid transport|,phospholipid binding|lipid binding|phosphatidylinositol transporter activity|,10,0.1,0.0989,10,0.9,3.1,0.3,0.532,0.532,0.753,0,0,-0.6,2
ENSMUSG00000022899,SLC15A2,"solute carrier family 15 (H+/peptide transporter), member 2",integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|oligopeptide transport|antibiotic transport|dipeptide transport|,high affinity oligopeptide transporter activity|antibiotic transporter activity|dipeptide transporter activity|,10,-0.8,1.66,10,0.6,2.38,-0.1,0.532,-0.532,0.753,0,0,-1.6,1.7
ENSMUSG00000021700,RAB3C,"RAB3C, member RAS oncogene family",cytosol|plasma membrane|synaptic vesicle|membrane|vesicle|perinuclear region of cytoplasm|,transport|small GTPase mediated signal transduction|protein transport|regulation of exocytosis|antigen processing and presentation|,nucleotide binding|protein binding|GTP binding|,10,0.6,1.86,10,0,0,0.3,0.531,0.531,0.754,0,0,-1.2,1.8
ENSMUSG00000016256,CTSZ,cathepsin Z,extracellular space|lysosome|endoplasmic reticulum|intracellular membrane-bounded organelle|extracellular vesicular exosome|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0,0,10,0.3,1.34,0.2,0.53,0.53,0.754,0,0,-0.8,1.8
ENSMUSG00000057378,RYR3,ryanodine receptor 3,endoplasmic reticulum|membrane|integral component of membrane|sarcoplasmic reticulum|junctional membrane complex|sarcoplasmic reticulum membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,transport|ion transport|calcium ion transport|cellular calcium ion homeostasis|striated muscle contraction|negative regulation of cytosolic calcium ion concentration|transmembrane transport|calcium ion transmembrane transport|,ion channel activity|ryanodine-sensitive calcium-release channel activity|calcium channel activity|calcium ion binding|calmodulin binding|calcium-release channel activity|calcium-induced calcium release activity|,10,0.3,1.22,10,-0.2,0.111,0.1,0.529,0.529,0.754,0,0,-1.5,1.4
ENSMUSG00000042605,ATXN2,ataxin 2,nucleus|cytoplasm|cytoplasm|Golgi apparatus|trans-Golgi network|polysome|cytoplasmic stress granule|membrane|ribonucleoprotein complex|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,negative regulation of receptor internalization|cerebellar Purkinje cell differentiation|cytoplasmic mRNA processing body assembly|stress granule assembly|negative regulation of multicellular organism growth|neuron projection morphogenesis|homeostasis of number of cells|neuromuscular process|,epidermal growth factor receptor binding|protein C-terminus binding|poly(A) RNA binding|,10,-0.1,0.394,10,-0.1,0.181,-0.1,0.526,-0.526,0.755,0,0,-0.9,1.9
ENSMUSG00000042345,UBASH3A,"ubiquitin associated and SH3 domain containing, A",nucleus|cytoplasm|cytosol|,regulation of cytokine production|negative regulation of T cell receptor signaling pathway|,catalytic activity|,9,0.1,0.323,9,-1.1,2.01,0.1,0.526,0.526,0.755,0,0,-2,0.9
ENSMUSG00000037990,SH3RF3,SH3 domain containing ring finger 3,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0,0,10,0.6,1.46,0.1,0.523,0.523,0.756,0,0,-1.1,1.9
ENSMUSG00000039033,TASP1,"taspase, threonine aspartase 1",None,"proteolysis|positive regulation of transcription, DNA-templated|",threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,0.3,1.05,10,0,0,0.1,0.52,0.52,0.757,0,0,-0.7,1.9
ENSMUSG00000031555,ADAM9,a disintegrin and metallopeptidase domain 9 (meltrin gamma),extracellular space|extracellular space|cytoplasm|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|basolateral plasma membrane|intrinsic component of external side of plasma membrane|,activation of MAPKK activity|proteolysis|membrane protein ectodomain proteolysis|membrane protein ectodomain proteolysis|cell adhesion|cell-matrix adhesion|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|integrin-mediated signaling pathway|response to manganese ion|cell adhesion mediated by integrin|positive regulation of cell adhesion mediated by integrin|positive regulation of macrophage fusion|response to tumor necrosis factor|monocyte activation|response to hydrogen peroxide|positive regulation of protein secretion|positive regulation of membrane protein ectodomain proteolysis|PMA-inducible membrane protein ectodomain proteolysis|response to glucocorticoid|positive regulation of keratinocyte migration|response to calcium ion|cellular response to lipopolysaccharide|,metalloendopeptidase activity|metalloendopeptidase activity|protein kinase C binding|integrin binding|protein binding|collagen binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|SH3 domain binding|SH3 domain binding|laminin binding|metal ion binding|,10,-0.4,0.918,10,-0.1,0.00438,-0.2,0.518,-0.518,0.757,0,0,-1.7,1.1
ENSMUSG00000001687,UBL3,ubiquitin-like 3,intracellular|plasma membrane|membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,7,0.3,1.63,7,0,0,0.2,0.513,0.513,0.759,0,0,-1.1,1.9
ENSMUSG00000033728,LRRC14,leucine rich repeat containing 14,cellular_component|,biological_process|,molecular_function|,10,0.1,0.374,10,0.1,0.186,0.1,0.512,0.512,0.759,0,0,-1,1.8
ENSMUSG00000055945,PRR18,proline rich 18,cellular_component|,biological_process|,molecular_function|,10,0.2,0.639,10,0.1,0.0381,0.2,0.509,0.509,0.76,0,0,-0.9,1.8
ENSMUSG00000019975,IKBIP,IKBKB interacting protein,endoplasmic reticulum|endoplasmic reticulum|membrane|membrane|integral component of membrane|,None,molecular_function|,10,-0.1,0.0443,10,-0.3,0.917,-0.2,0.507,-0.507,0.76,0,0,-1.5,1.6
ENSMUSG00000006676,USP19,ubiquitin specific peptidase 19,endoplasmic reticulum|endoplasmic reticulum membrane|cytosol|membrane|integral component of membrane|,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|ER-associated ubiquitin-dependent protein catabolic process|regulation of protein stability|negative regulation of skeletal muscle tissue development|positive regulation of cell cycle process|regulation of cellular response to hypoxia|,ubiquitin-specific protease activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|metal ion binding|,10,0,0,10,-0.3,1.46,-0.1,0.505,-0.505,0.761,0,0,-1.2,1.7
ENSMUSG00000029992,GFPT1,glutamine fructose-6-phosphate transaminase 1,extracellular vesicular exosome|,carbohydrate metabolic process|fructose 6-phosphate metabolic process|glucosamine biosynthetic process|UDP-N-acetylglucosamine metabolic process|glutamine metabolic process|metabolic process|carbohydrate biosynthetic process|circadian regulation of gene expression|negative regulation of glycogen biosynthetic process|rhythmic process|protein homotetramerization|,glutamine-fructose-6-phosphate transaminase (isomerizing) activity|transaminase activity|amino acid binding|transferase activity|carbohydrate binding|,10,0.1,0.307,10,0.1,0.246,0.1,0.505,0.505,0.761,0,0,-1,1.7
ENSMUSG00000030945,ACSM2,acyl-CoA synthetase medium-chain family member 2,mitochondrion|,lipid metabolic process|fatty acid metabolic process|metabolic process|medium-chain fatty-acyl-CoA metabolic process|,nucleotide binding|catalytic activity|ATP binding|ligase activity|metal ion binding|butyrate-CoA ligase activity|,10,-0.1,0.428,10,-0.1,0.107,-0.1,0.49,-0.49,0.765,0,0,-1.6,1.2
ENSMUSG00000028221,TMEM55A,transmembrane protein 55A,cellular_component|lysosome|endosome|membrane|integral component of membrane|,biological_process|,molecular_function|hydrolase activity|,10,0.2,0.162,10,0.2,0.363,0.2,0.48,0.48,0.767,0,0,-0.9,1.8
ENSMUSG00000030592,RYR1,"ryanodine receptor 1, skeletal muscle",intracellular|cell|cytoplasm|smooth endoplasmic reticulum|plasma membrane|cell cortex|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|junctional membrane complex|T-tubule|extrinsic component of cytoplasmic side of plasma membrane|I band|sarcoplasmic reticulum membrane|sarcoplasmic reticulum membrane|sarcolemma|protein complex|extracellular vesicular exosome|,response to hypoxia|outflow tract morphogenesis|transport|ion transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|muscle contraction|muscle contraction|regulation of muscle contraction|multicellular organismal development|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|response to caffeine|regulation of ion transmembrane transport|skin development|ossification involved in bone maturation|skeletal muscle fiber development|release of sequestered calcium ion into cytosol|release of sequestered calcium ion into cytosol|cytosolic calcium ion homeostasis|transmembrane transport|sarcoplasmic reticulum calcium ion transport|calcium ion transmembrane transport|cellular response to caffeine|,protease binding|ion channel activity|ryanodine-sensitive calcium-release channel activity|ryanodine-sensitive calcium-release channel activity|voltage-gated calcium channel activity|calcium channel activity|calcium ion binding|protein binding|calmodulin binding|enzyme binding|,10,0.1,0.0231,10,0.1,0.497,0.1,0.478,0.478,0.767,0,0,-1.2,1.6
ENSMUSG00000038264,SEMA7A,"sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A",plasma membrane|external side of plasma membrane|membrane|anchored component of membrane|,osteoblast differentiation|positive regulation of protein phosphorylation|inflammatory response|integrin-mediated signaling pathway|integrin-mediated signaling pathway|multicellular organismal development|nervous system development|olfactory lobe development|olfactory lobe development|cell differentiation|neuron projection development|positive regulation of axon extension|positive regulation of axon extension|axon extension|axon extension|axon extension|regulation of inflammatory response|positive regulation of macrophage cytokine production|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|,receptor activity|integrin binding|,10,-0.2,1.25,10,0.2,0.645,0.1,0.477,0.477,0.768,0,0,-1.3,1.4
ENSMUSG00000028238,ATP6V0D2,"ATPase, H+ transporting, lysosomal V0 subunit D2","endosome|early endosome|membrane|apical plasma membrane|vacuolar proton-transporting V-type ATPase complex|proton-transporting V-type ATPase, V0 domain|extracellular vesicular exosome|",transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|,hydrogen ion transmembrane transporter activity|,10,0.1,0.65,10,-0.3,1.22,-0.3,0.476,-0.476,0.768,0,0,-1.5,1.1
ENSMUSG00000057335,CEP170,centrosomal protein 170,cytoplasm|centrosome|centriole|cytoskeleton|microtubule|nuclear membrane|,biological_process|,molecular_function|,10,0.3,0.266,10,0.1,0.336,0.1,0.474,0.474,0.768,0,0,-0.6,2
ENSMUSG00000025571,TNRC6C,trinucleotide repeat containing 6C,cellular_component|,"endoderm formation|regulation of translation|endoderm development|gene silencing by RNA|embryonic hemopoiesis|embryonic organ development|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|regulation of gene silencing by miRNA|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|",nucleotide binding|molecular_function|nucleic acid binding|RNA binding|,10,-0.2,0.53,10,-1,1.74,-0.6,0.474,-0.474,0.768,0,0,-2,1
ENSMUSG00000005611,MRVI1,MRV integration site 1,intracellular|cytoplasm|membrane|integral component of membrane|sarcoplasmic reticulum|,cGMP-mediated signaling|negative regulation of smooth muscle contraction|relaxation of vascular smooth muscle|,protein binding|,10,0.4,1.24,10,0,0,0.1,0.471,0.471,0.769,0,0,-0.8,1.8
ENSMUSG00000005823,GPR108,G protein-coupled receptor 108,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.32,10,0.2,0.195,0.2,0.471,0.471,0.769,0,0,-1,1.7
ENSMUSG00000009092,DERL3,"Der1-like domain family, member 3",endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,protein N-linked glycosylation via asparagine|ER-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum unfolded protein response|,None,10,0,0,10,-0.2,1.69,-0.1,0.465,-0.465,0.771,0,0,-1,2
ENSMUSG00000029804,HERC3,hect domain and RLD 3,nucleus|cytoplasm|,protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,ubiquitin-protein transferase activity|ligase activity|,10,-0.1,0.206,10,0.8,1.33,-0.1,0.46,-0.46,0.772,0,0,-0.7,2
ENSMUSG00000064181,RAB3IP,RAB3A interacting protein,nucleus|cytoplasm|centrosome|cytosol|cytoskeleton|cell projection|,transport|protein transport|positive regulation of Rab GTPase activity|protein localization to organelle|cilium assembly|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|GTPase binding|,10,0.3,1.04,10,-0.2,0.266,0.2,0.46,0.46,0.772,0,0,-1.2,1.6
ENSMUSG00000062515,FABP4,"fatty acid binding protein 4, adipocyte",nucleus|cytoplasm|cytosol|,"cytokine production|negative regulation of protein kinase activity|fatty acid metabolic process|transport|positive regulation of cell proliferation|cholesterol homeostasis|negative regulation of transcription, DNA-templated|positive regulation of inflammatory response|white fat cell differentiation|brown fat cell differentiation|cellular response to lithium ion|",transporter activity|lipid binding|,10,-0.3,0.93,10,0,0,-0.3,0.458,-0.458,0.772,0,0,-1.8,0.8
ENSMUSG00000026121,SEMA4C,"sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C",extracellular space|plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|synaptic vesicle membrane|cytoplasmic vesicle|synapse|postsynaptic membrane|,neural tube closure|multicellular organismal development|nervous system development|cell migration in hindbrain|cerebellum development|cell differentiation|positive regulation of stress-activated MAPK cascade|muscle cell differentiation|muscle cell differentiation|semaphorin-plexin signaling pathway|,receptor activity|protein binding|,10,0,0,10,-0.4,0.868,-0.4,0.457,-0.457,0.773,0,0,-1.9,0.7
ENSMUSG00000027996,SFRP2,secreted frizzled-related protein 2,extracellular region|extracellular space|extracellular space|cytoplasm|plasma membrane|,"patterning of blood vessels|somitogenesis|neural tube closure|chondrocyte development|outflow tract morphogenesis|cardiac left ventricle morphogenesis|apoptotic process|signal transduction|multicellular organismal development|brain development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|male gonad development|anterior/posterior pattern specification|negative regulation of gene expression|negative regulation of cardiac muscle cell apoptotic process|negative regulation of epithelial to mesenchymal transition|positive regulation of endopeptidase activity|Wnt signaling pathway|neural tube development|regulation of Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|collagen fibril organization|positive regulation of cell growth|negative regulation of cell growth|negative regulation of cell migration|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|cellular response to extracellular stimulus|positive regulation of peptidyl-serine phosphorylation|positive regulation of catenin import into nucleus|post-anal tail morphogenesis|regulation of cell proliferation|response to drug|negative regulation of mesodermal cell fate specification|embryonic digit morphogenesis|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of JUN kinase activity|positive regulation of fat cell differentiation|positive regulation of osteoblast differentiation|positive regulation of angiogenesis|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|development of primary male sexual characteristics|digestive tract morphogenesis|negative regulation of epithelial cell proliferation|negative regulation of peptidyl-tyrosine phosphorylation|cartilage development|convergent extension involved in axis elongation|bone morphogenesis|negative regulation of dermatome development|hematopoietic stem cell proliferation|cellular response to X-ray|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|regulation of establishment of planar polarity|planar cell polarity pathway involved in neural tube closure|Wnt signaling pathway involved in somitogenesis|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|regulation of stem cell division|negative regulation of planar cell polarity pathway involved in axis elongation|positive regulation of receptor activity|",protein binding|metalloenzyme activator activity|Wnt-protein binding|PDZ domain binding|Wnt-activated receptor activity|receptor agonist activity|endopeptidase activator activity|,10,0.5,0.626,10,-0.1,0.377,-0.1,0.457,-0.457,0.773,0,0,-1.1,1.8
ENSMUSG00000020323,PRSS57,"protease, serine 57",cellular_component|extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.781,10,0,0,0.1,0.456,0.456,0.773,0,0,-1.3,1.6
ENSMUSG00000026980,LY75,lymphocyte antigen 75,external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,endocytosis|,carbohydrate binding|,10,-0.1,0.00543,10,-0.2,0.611,-0.1,0.443,-0.443,0.776,0,0,-1.3,1.7
ENSMUSG00000052981,UBE2QL1,ubiquitin-conjugating enzyme E2Q family-like 1,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|ligase activity|acid-amino acid ligase activity|,10,-0.2,1.04,10,0,0,-0.1,0.443,-0.443,0.776,0,0,-1.4,1.4
ENSMUSG00000055720,UBL7,ubiquitin-like 7 (bone marrow stromal cell-derived),cellular_component|,biological_process|,molecular_function|,10,0.2,1.09,10,0,0,0.1,0.442,0.442,0.777,0,0,-1.6,1.4
ENSMUSG00000058388,PHTF1,putative homeodomain transcription factor 1,nucleus|endoplasmic reticulum|cis-Golgi network|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|,10,0.2,1.23,10,-0.2,1.44,-0.1,0.438,-0.438,0.778,0,0,-1.5,1.3
ENSMUSG00000026173,PLCD4,"phospholipase C, delta 4",intracellular|cell|nucleus|cytoplasm|endoplasmic reticulum|membrane|,lipid metabolic process|signal transduction|acrosome reaction|lipid catabolic process|intracellular signal transduction|phosphatidylinositol metabolic process|,phosphatidylinositol phospholipase C activity|phospholipase C activity|signal transducer activity|calcium ion binding|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|,10,0.4,1.16,10,-0.4,1.45,-0.1,0.436,-0.436,0.778,0,0,-1.4,1.5
ENSMUSG00000026833,OLFM1,olfactomedin 1,extracellular region|extracellular space|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|,multicellular organismal development|protein oligomerization|regulation of beta-amyloid formation|negative regulation of beta-amyloid formation|negative regulation of neuron migration|,beta-amyloid binding|protein binding|,10,-0.9,0.505,10,-0.2,0.351,-0.1,0.433,-0.433,0.779,0,0,-2,0.9
ENSMUSG00000030302,ATP2B2,"ATPase, Ca++ transporting, plasma membrane 2",cytoplasm|endoplasmic reticulum|plasma membrane|plasma membrane|cilium|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|dendrite|neuronal cell body membrane|neuronal cell body|neuronal cell body|membrane raft|,cell morphogenesis|ATP catabolic process|transport|ion transport|cation transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|organelle organization|lactation|sensory perception of sound|sensory perception of sound|sensory perception of sound|locomotory behavior|regulation of cell size|cerebellum development|cerebellar Purkinje cell layer morphogenesis|cerebellar Purkinje cell differentiation|cerebellar granule cell differentiation|neuron differentiation|locomotion|serotonin metabolic process|inner ear morphogenesis|otolith mineralization|cGMP metabolic process|regulation of synaptic plasticity|inner ear development|synapse organization|neuromuscular process controlling balance|detection of mechanical stimulus involved in sensory perception of sound|cytosolic calcium ion homeostasis|cytosolic calcium ion homeostasis|positive regulation of calcium ion transport|auditory receptor cell stereocilium organization|inner ear receptor cell differentiation|calcium ion transmembrane transport|cochlea development|calcium ion export|,nucleotide binding|calcium-transporting ATPase activity|calcium ion binding|calmodulin binding|ATP binding|protein C-terminus binding|hydrolase activity|cation-transporting ATPase activity|PDZ domain binding|calcium-dependent ATPase activity|acetylcholine receptor binding|glutamate receptor binding|metal ion binding|,9,0,0,9,-0.2,0.712,-0.2,0.427,-0.427,0.781,0,0,-1.7,1.2
ENSMUSG00000053375,ATP6V1E2,"ATPase, H+ transporting, lysosomal V1 subunit E2","acrosomal vesicle|proton-transporting two-sector ATPase complex, catalytic domain|",ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|proton-transporting ATPase activity, rotational mechanism|",10,0,0,10,-0.4,2.15,-0.2,0.426,-0.426,0.781,0,0,-1.3,1.5
ENSMUSG00000037366,PAFAH2,platelet-activating factor acetylhydrolase 2,cytoplasm|,lipid metabolic process|lipid catabolic process|negative regulation of apoptotic process|,1-alkyl-2-acetylglycerophosphocholine esterase activity|hydrolase activity|,10,-0.1,0.0457,10,-0.1,0.416,-0.1,0.423,-0.423,0.782,0,0,-1.2,1.6
ENSMUSG00000023057,FABP2,"fatty acid binding protein 2, intestinal",intracellular|cytoplasm|plasma membrane|microvillus|apical cortex|,fatty acid metabolic process|transport|long-chain fatty acid transport|intestinal absorption|,transporter activity|long-chain fatty acid transporter activity|fatty acid binding|lipid binding|,10,0.2,0.221,10,-0.2,0.302,0.2,0.421,0.421,0.782,0,0,-1.4,1.4
ENSMUSG00000068184,NDUFAF2,"NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2",mitochondrion|,respiratory electron transport chain|cellular respiration|negative regulation of insulin secretion involved in cellular response to glucose stimulus|reactive oxygen species metabolic process|,NADH dehydrogenase (ubiquinone) activity|,10,0.2,0.857,10,0,0,0.1,0.42,0.42,0.782,0,0,-1.2,1.6
ENSMUSG00000002395,USE1,unconventional SNARE in the ER 1 homolog (S. cerevisiae),endoplasmic reticulum|membrane|integral component of membrane|,transport|endoplasmic reticulum organization|protein transport|vesicle-mediated transport|regulation of ER to Golgi vesicle-mediated transport|endoplasmic reticulum tubular network organization|,None,10,-0.1,0.483,10,0.2,0.598,-0.2,0.42,-0.42,0.782,0,0,-1.8,1
ENSMUSG00000021072,TMX1,thioredoxin-related transmembrane protein 1,nucleolus|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,protein folding|transport|response to endoplasmic reticulum stress|response to endoplasmic reticulum stress|cell redox homeostasis|oxidation-reduction process|,protein disulfide isomerase activity|disulfide oxidoreductase activity|,10,-0.2,0.364,10,0.1,0.15,-0.1,0.417,-0.417,0.783,0,0,-1.4,1.3
ENSMUSG00000023460,RAB12,"RAB12, member RAS oncogene family",intracellular|cell|lysosome|endosome|Golgi apparatus|membrane|secretory granule|recycling endosome membrane|,transport|small GTPase mediated signal transduction|endosome to lysosome transport|protein transport|cellular protein catabolic process|,nucleotide binding|GTP binding|GDP binding|,10,-0.3,1.63,10,0.3,1.06,-0.2,0.417,-0.417,0.783,0,0,-1.5,1.3
ENSMUSG00000030598,FBXO17,F-box protein 17,SCF ubiquitin ligase complex|,biological_process|,glycoprotein binding|,10,0,0,10,-0.1,0.573,-0.1,0.415,-0.415,0.784,0,0,-1.1,2
ENSMUSG00000020676,CCL11,chemokine (C-C motif) ligand 11,extracellular region|extracellular space|intracellular|,positive regulation of endothelial cell proliferation|mast cell chemotaxis|chemotaxis|inflammatory response|immune response|cytoskeleton organization|actin filament organization|regulation of cell shape|positive regulation of cell migration|positive regulation of actin filament polymerization|positive regulation of Rac GTPase activity|positive regulation of angiogenesis|eosinophil chemotaxis|branching involved in mammary gland duct morphogenesis|mammary duct terminal end bud growth|ERK1 and ERK2 cascade|,cytokine activity|chemokine activity|,10,0.7,0.159,10,0.2,0.776,0.1,0.414,0.414,0.784,0,0,-0.7,1.9
ENSMUSG00000090262,MPV17,MpV17 mitochondrial inner membrane protein,mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|peroxisome|membrane|integral component of membrane|,mitochondrial genome maintenance|sensory perception of sound|glomerular basement membrane development|cellular response to reactive oxygen species|homeostatic process|inner ear development|reactive oxygen species metabolic process|regulation of reactive oxygen species metabolic process|,None,10,0.3,0.852,10,-0.4,2.51,0.6,0.412,0.412,0.784,0,0,-1.1,1.8
ENSMUSG00000030935,ACSM3,acyl-CoA synthetase medium-chain family member 3,mitochondrion|mitochondrial matrix|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|metabolic process|,nucleotide binding|catalytic activity|ATP binding|fatty acid ligase activity|ligase activity|metal ion binding|butyrate-CoA ligase activity|,10,0.3,1.04,10,0,0,0.3,0.409,0.409,0.785,0,0,-0.6,1.9
ENSMUSG00000022367,HAS2,hyaluronan synthase 2,integral component of plasma membrane|membrane|integral component of membrane|,vasculogenesis|positive regulation of cell proliferation|hyaluronan metabolic process|hyaluronan biosynthetic process|hyaluronan biosynthetic process|positive regulation of cell migration|cellular response to platelet-derived growth factor stimulus|atrioventricular canal development|extracellular polysaccharide biosynthetic process|bone morphogenesis|extracellular matrix assembly|endocardial cushion to mesenchymal transition|positive regulation of monocyte aggregation|,"transferase activity|transferase activity, transferring glycosyl groups|hyaluronan synthase activity|hyaluronan synthase activity|",10,0.2,0.535,10,0.1,0.0882,0.1,0.406,0.406,0.786,0,0,-1,1.8
ENSMUSG00000039021,TTC16,tetratricopeptide repeat domain 16,cellular_component|,biological_process|,molecular_function|,10,0.1,0.438,10,-0.1,0.425,0.1,0.406,0.406,0.786,0,0,-1.4,1.5
ENSMUSG00000028070,APOA1BP,apolipoprotein A-I binding protein,extracellular region|extracellular space|mitochondrion|cilium|cell body|extracellular vesicular exosome|,protein homotetramerization|,nucleotide binding|isomerase activity|protein homodimerization activity|metal ion binding|,10,0.1,0.448,10,-0.4,2.35,-0.3,0.403,-0.403,0.787,0,0,-1.6,1.1
ENSMUSG00000027168,PAX6,paired box 6,nuclear chromatin|nuclear chromatin|intracellular|nucleus|nucleus|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|blood vessel development|cell fate determination|neural crest cell migration|neuron migration|neuron migration|negative regulation of protein phosphorylation|positive regulation of neuroblast proliferation|epithelial cell development|lens development in camera-type eye|type B pancreatic cell differentiation|type B pancreatic cell differentiation|pancreatic A cell differentiation|pancreatic A cell development|pancreatic A cell development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|smoothened signaling pathway|multicellular organismal development|axonogenesis|axon guidance|brain development|brain development|salivary gland morphogenesis|negative regulation of cell proliferation|dorsal/ventral axis specification|anterior/posterior pattern specification|anterior/posterior pattern specification|dorsal/ventral pattern formation|regulation of gene expression|positive regulation of gene expression|positive regulation of gene expression|regulation of neuron projection development|pallium development|rhombomere morphogenesis|olfactory bulb development|oligodendrocyte cell fate specification|cerebral cortex regionalization|forebrain anterior/posterior pattern specification|forebrain dorsal/ventral pattern formation|commitment of neuronal cell to specific neuron type in forebrain|forebrain-midbrain boundary formation|regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification|regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification|regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment|telencephalon regionalization|pituitary gland development|interkinetic nuclear migration|signal transduction involved in regulation of gene expression|cell differentiation|keratinocyte differentiation|regulation of cell migration|positive regulation of epithelial cell differentiation|forebrain development|hindbrain development|lacrimal gland development|protein localization to organelle|eye photoreceptor cell development|glucose homeostasis|positive regulation of cell fate specification|camera-type eye development|camera-type eye development|cell fate commitment|cell fate commitment|regulation of neuron differentiation|negative regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of timing of cell differentiation|embryonic camera-type eye morphogenesis|astrocyte differentiation|astrocyte differentiation|negative regulation of epithelial cell proliferation|regulation of neurogenesis|regulation of neurogenesis|retina development in camera-type eye|iris morphogenesis|cornea development in camera-type eye|neural precursor cell proliferation|positive regulation of glucagon secretion|insulin metabolic process|negative regulation of neural precursor cell proliferation|positive regulation of neuron migration|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|AT DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein kinase binding|ubiquitin protein ligase binding|histone acetyltransferase binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|co-SMAD binding|R-SMAD binding|R-SMAD binding|HMG box domain binding|,9,0,0,9,0.2,0.736,0.1,0.4,0.4,0.788,0,0,-1.2,1.6
ENSMUSG00000026640,PLXNA2,plexin A2,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|multicellular organismal development|cerebellar granule cell precursor tangential migration|regulation of cell migration|centrosome localization|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|,receptor activity|semaphorin receptor activity|semaphorin receptor activity|semaphorin receptor activity|,10,0,0,10,-0.6,2.26,-0.1,0.4,-0.4,0.788,0,0,-2,0.5
ENSMUSG00000051675,TRIM32,tripartite motif-containing 32,intracellular|nucleus|cytoplasm|striated muscle myosin thick filament|,protein polyubiquitination|response to UV|protein ubiquitination|protein ubiquitination|positive regulation of cell growth|positive regulation of cell migration|negative regulation of viral transcription|response to tumor necrosis factor|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|positive regulation of neuron differentiation|positive regulation of protein catabolic process|positive regulation of cell cycle|positive regulation of proteolysis|positive regulation of neurogenesis|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|negative regulation of keratinocyte apoptotic process|negative regulation of viral release from host cell|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of cell motility|,"RNA binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|myosin binding|ribosomal S6-glutamic acid ligase activity|translation initiation factor binding|ubiquitin binding|protein self-association|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.0602,10,-0.1,0.374,-0.1,0.397,-0.397,0.788,0,0,-1.8,1
ENSMUSG00000020088,SAR1A,SAR1 gene homolog A (S. cerevisiae),intracellular|endoplasmic reticulum|Golgi apparatus|sarcoplasmic reticulum|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|regulation of cargo loading into COPII-coated vesicle|negative regulation of cargo loading into COPII-coated vesicle|,nucleotide binding|GTP binding|,10,0.5,0.314,10,0.1,0.279,0.2,0.391,0.391,0.79,0,0,-0.9,1.8
ENSMUSG00000018770,ATP5G3,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)","mitochondrion|membrane|integral component of membrane|proton-transporting two-sector ATPase complex, proton-transporting domain|proton-transporting ATP synthase complex, coupling factor F(o)|",transport|ion transport|biological_process|ATP synthesis coupled proton transport|ATP hydrolysis coupled proton transport|proton transport|,lipid binding|hydrogen ion transmembrane transporter activity|,10,-0.1,0.395,10,0.9,0.967,-0.1,0.388,-0.388,0.791,0,0,-0.8,2
ENSMUSG00000038132,RBM24,RNA binding motif protein 24,cellular_component|nucleus|cytoplasm|,regulation of myotube differentiation|cell differentiation|regulation of mRNA stability|,nucleotide binding|nucleic acid binding|RNA binding|mRNA 3'-UTR binding|,10,0,0,10,0.2,1.15,0.1,0.385,0.385,0.792,0,0,-1.2,1.6
ENSMUSG00000001493,MEOX1,mesenchyme homeobox 1,nucleus|,"somite specification|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|HMG box domain binding|,10,0,0,10,-0.2,0.944,-0.1,0.385,-0.385,0.792,0,0,-1.6,1.2
ENSMUSG00000030319,CAND2,cullin-associated and neddylation-dissociated 2 (putative),intracellular|nucleus|nucleus|,None,protein binding|TBP-class protein binding|TBP-class protein binding|,10,0.1,0.419,10,0,0,0.1,0.384,0.384,0.792,0,0,-1.1,1.7
ENSMUSG00000043262,UEVLD,UEV and lactate/malate dehyrogenase domains,extracellular vesicular exosome|,carbohydrate metabolic process|cellular protein modification process|protein transport|cellular carbohydrate metabolic process|oxidation-reduction process|,"catalytic activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|",10,0.6,0.711,10,-0.1,0.0428,-0.1,0.384,-0.384,0.792,0,0,-0.9,2
ENSMUSG00000018973,HOXB1,homeobox B1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anatomical structure morphogenesis|anterior/posterior pattern specification|rhombomere development|rhombomere 4 development|rhombomere 5 development|facial nerve structural organization|facial nucleus development|positive regulation of transcription from RNA polymerase II promoter|anatomical structure formation involved in morphogenesis|embryonic skeletal system morphogenesis|",DNA binding|DNA binding|DNA binding|protein domain specific binding|sequence-specific DNA binding|,10,0.2,0.397,10,0.1,0.056,0.1,0.383,0.383,0.793,0,0,-0.8,1.9
ENSMUSG00000063760,RNF217,ring finger protein 217,cellular_component|membrane|integral component of membrane|,biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.4,1.33,10,0.1,0.118,-0.3,0.379,-0.379,0.794,0,0,-1.8,0.8
ENSMUSG00000036270,EDC4,enhancer of mRNA decapping 4,cytoplasmic mRNA processing body|nucleus|cytoplasm|membrane|intracellular membrane-bounded organelle|,biological_process|,protein binding|,10,-0.1,0.127,10,0.8,1.93,0.1,0.379,0.379,0.794,0,0,-0.7,2
ENSMUSG00000028996,RBP7,"retinol binding protein 7, cellular",cytoplasm|,transport|,transporter activity|retinoid binding|lipid binding|retinal binding|retinol binding|,10,0.2,0.748,10,0,0,0.1,0.379,0.379,0.794,0,0,-0.9,1.8
ENSMUSG00000041921,METAP1D,methionyl aminopeptidase type 1D (mitochondrial),mitochondrion|mitochondrion|,proteolysis|,aminopeptidase activity|peptidase activity|metalloexopeptidase activity|hydrolase activity|metal ion binding|,10,0.2,0.488,10,-0.2,0.659,-0.1,0.378,-0.378,0.794,0,0,-1.5,1.3
ENSMUSG00000029629,PHF14,PHD finger protein 14,nucleus|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of cell proliferation|lung alveolus development|negative regulation of mesenchymal cell proliferation|negative regulation of platelet-derived growth factor receptor-alpha signaling pathway|negative regulation of mesenchymal cell proliferation involved in lung development|,molecular_function|zinc ion binding|metal ion binding|,10,0.2,0.414,10,0.1,0.123,0.1,0.376,0.376,0.794,0,0,-1.1,1.7
ENSMUSG00000034785,DIO1,"deiodinase, iodothyronine, type I",endoplasmic reticulum|membrane|integral component of membrane|,hormone biosynthetic process|oxidation-reduction process|,thyroxine 5'-deiodinase activity|thyroxine 5'-deiodinase activity|selenium binding|oxidoreductase activity|,10,-0.4,0.956,10,0,0,-0.2,0.376,-0.376,0.794,0,0,-1.8,1
ENSMUSG00000026107,NABP1,nucleic acid binding protein 1,nucleus|nucleus|cytoplasm|SOSS complex|,double-strand break repair via homologous recombination|DNA repair|cellular response to DNA damage stimulus|mitotic cell cycle checkpoint|response to ionizing radiation|,nucleic acid binding|DNA binding|single-stranded DNA binding|RNA binding|,10,-0.2,0.623,10,0.2,0.569,0.1,0.372,0.372,0.796,0,0,-1.2,1.5
ENSMUSG00000062713,SIM2,single-minded homolog 2 (Drosophila),nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|multicellular organismal development|nervous system development|embryonic pattern specification|cell differentiation|lung development|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|protein binding|protein heterodimerization activity|protein dimerization activity|,10,0,0,10,0.5,0.828,0.6,0.369,0.369,0.796,0,0,-0.4,2
ENSMUSG00000061259,TMPRSS11D,"transmembrane protease, serine 11d",extracellular region|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,proteolysis|proteolysis|regulation of growth|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.344,10,0.1,0.0563,0.1,0.367,0.367,0.797,0,0,-1.3,1.5
ENSMUSG00000012429,MPLKIP,M-phase specific PLK1 intereacting protein,nucleus|cytoplasm|centrosome|cytoskeleton|midbody|,cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,10,0.2,1.16,10,0,0,0.1,0.367,0.367,0.797,0,0,-1.6,1.2
ENSMUSG00000029330,CDS1,CDP-diacylglycerol synthase 1,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,lipid metabolic process|phosphatidylinositol biosynthetic process|phospholipid biosynthetic process|CDP-diacylglycerol biosynthetic process|,"phosphatidate cytidylyltransferase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|nucleotidyltransferase activity|",10,0,0,10,0.2,0.58,0.1,0.366,0.366,0.797,0,0,-0.5,2
ENSMUSG00000031903,PLA2G15,"phospholipase A2, group XV",extracellular region|mitochondrion|lysosome|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|ceramide metabolic process|phosphatidylcholine metabolic process|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|hydrolase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|calcium-independent phospholipase A2 activity|calcium-independent phospholipase A2 activity|peptidyl-lysine N-acetyltransferase activity|",10,0.3,1.28,10,-0.3,1.7,0.2,0.364,0.364,0.798,0,0,-1.3,1.4
ENSMUSG00000028185,DNASE2B,deoxyribonuclease II beta,extracellular region|cytoplasm|lysosome|,"DNA catabolic process, endonucleolytic|DNA metabolic process|apoptotic DNA fragmentation|",nuclease activity|endonuclease activity|endodeoxyribonuclease activity|deoxyribonuclease II activity|deoxyribonuclease II activity|hydrolase activity|,10,-0.3,1.72,10,0.3,0.82,-0.2,0.364,-0.364,0.798,0,0,-1.6,1.3
ENSMUSG00000030670,CYP2R1,"cytochrome P450, family 2, subfamily r, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,calcitriol biosynthetic process from calciol|vitamin D metabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|vitamin D3 25-hydroxylase activity|metal ion binding|cholestanetriol 26-monooxygenase activity|",10,0,0,10,0.2,0.515,0.2,0.363,0.363,0.798,0,0,-1.2,1.8
ENSMUSG00000059816,FAM159A,"family with sequence similarity 159, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.51,10,0,0,0.1,0.362,0.362,0.799,0,0,-0.8,1.9
ENSMUSG00000062901,KLHL24,kelch-like 24,cellular_component|cytoplasm|cell projection|,biological_process|,molecular_function|,10,-0.1,0.276,10,-1.1,1.87,-0.1,0.36,-0.36,0.799,0,0,-2,1.1
ENSMUSG00000022057,ADAMDEC1,"ADAM-like, decysin 1",cellular_component|extracellular region|,proteolysis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.0842,10,0.1,0.307,0.1,0.358,0.358,0.8,0,0,-1.2,1.7
ENSMUSG00000052160,PLD4,"phospholipase D family, member 4",nucleus|endoplasmic reticulum|membrane|integral component of membrane|trans-Golgi network membrane|phagocytic vesicle|,hematopoietic progenitor cell differentiation|lipid metabolic process|phagocytosis|metabolic process|lipid catabolic process|,catalytic activity|protein binding|hydrolase activity|N-acylphosphatidylethanolamine-specific phospholipase D activity|,10,-0.2,0.475,10,0.3,1.21,0.4,0.355,0.355,0.8,0,0,-0.8,1.9
ENSMUSG00000038840,BIRC7,baculoviral IAP repeat-containing 7 (livin),nucleus|cytoplasm|Golgi apparatus|,apoptotic process|negative regulation of peptidase activity|protein ubiquitination|regulation of cell proliferation|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of natural killer cell apoptotic process|,"ubiquitin-protein transferase activity|cysteine-type endopeptidase inhibitor activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|peptidase inhibitor activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,0.779,10,-0.3,2.42,-0.2,0.355,-0.355,0.8,0,0,-1.7,1.3
ENSMUSG00000071584,ATF7,activating transcription factor 7,nuclear periphery|,"regulation of transcription, DNA-templated|",transcription factor binding|enzyme binding|mitogen-activated protein kinase binding|,10,0.2,0.88,10,-0.1,0.0325,0.1,0.349,0.349,0.802,0,0,-1.1,1.6
ENSMUSG00000016626,NLRP14,"NLR family, pyrin domain containing 14",cellular_component|,multicellular organismal development|spermatogenesis|cell differentiation|,nucleotide binding|molecular_function|ATP binding|,10,0.1,0.0285,10,0.3,0.863,0.1,0.348,0.348,0.802,0,0,-1.1,1.7
ENSMUSG00000044628,RNF208,ring finger protein 208,cellular_component|,protein autoubiquitination|,ubiquitin-protein transferase activity|zinc ion binding|metal ion binding|,10,-0.2,1.2,10,0,0,-0.1,0.344,-0.344,0.803,0,0,-1.3,1.7
ENSMUSG00000030643,RAB30,"RAB30, member RAS oncogene family",cytoplasm|Golgi apparatus|cis-Golgi network|trans-Golgi network|membrane|Golgi cisterna|,Golgi organization|small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTP binding|,10,0,0,10,-0.6,2.45,-0.2,0.342,-0.342,0.804,0,0,-1.7,1.5
ENSMUSG00000022827,RABL3,"RAB, member RAS oncogene family-like 3",cellular_component|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0,0,10,0.2,1.06,0.1,0.342,0.342,0.804,0,0,-0.8,1.9
ENSMUSG00000022056,ADAM7,a disintegrin and metallopeptidase domain 7,plasma membrane|membrane|integral component of membrane|,proteolysis|integrin-mediated signaling pathway|,endopeptidase activity|metalloendopeptidase activity|metallopeptidase activity|zinc ion binding|,10,-0.1,0.218,10,-0.1,0.152,-0.1,0.338,-0.338,0.805,0,0,-1.7,1.1
ENSMUSG00000024388,MYO7B,myosin VIIB,cytoskeleton|plasma membrane|membrane|myosin complex|extracellular vesicular exosome|,None,nucleotide binding|motor activity|actin binding|ATP binding|,10,-0.2,0.472,10,0.1,0.169,-0.1,0.337,-0.337,0.805,0,0,-1.5,1.3
ENSMUSG00000025885,MYO5B,myosin VB,myosin complex|neuron projection|neuronal cell body|dendritic spine|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,transport|metabolic process|protein transport|vesicle-mediated transport|regulation of protein localization|,nucleotide binding|motor activity|actin binding|catalytic activity|calmodulin binding|ATP binding|Rab GTPase binding|ionotropic glutamate receptor binding|,10,0.1,0.0555,10,0.1,0.31,0.1,0.334,0.334,0.806,0,0,-1.1,1.7
ENSMUSG00000017858,IFT52,intraflagellar transport 52,intracellular|cell|centrosome|centriole|cilium|cilium|intraciliary transport particle B|photoreceptor connecting cilium|ciliary basal body|cell projection|dendrite terminus|ciliary tip|ciliary base|,neural tube formation|heart looping|smoothened signaling pathway|determination of left/right symmetry|dorsal/ventral pattern formation|intraciliary transport|intraciliary transport|embryonic digit morphogenesis|negative regulation of epithelial cell proliferation|cilium morphogenesis|regulation of protein processing|,protein binding|,10,0.1,0.241,10,0.7,0.444,0.1,0.333,0.333,0.807,0,0,-0.7,2
ENSMUSG00000048814,LONRF2,LON peptidase N-terminal domain and ring finger 2,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.2,0.718,10,0,0,-0.1,0.331,-0.331,0.807,0,0,-1.7,1.1
ENSMUSG00000028581,LAPTM5,lysosomal-associated protein transmembrane 5,lysosome|lysosomal membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|,None,10,0.1,0.258,10,0.1,0.105,0.1,0.331,0.331,0.807,0,0,-1,1.8
ENSMUSG00000037712,FERMT2,fermitin family homolog 2 (Drosophila),stress fiber|nucleus|cytoplasm|cytoskeleton|plasma membrane|focal adhesion|membrane|cell junction|extrinsic component of cytoplasmic side of plasma membrane|filamentous actin|cell projection|,cell adhesion|cell-matrix adhesion|cell-matrix adhesion|transforming growth factor beta receptor signaling pathway|integrin-mediated signaling pathway|regulation of cell shape|Wnt signaling pathway|integrin activation|integrin activation|substrate adhesion-dependent cell spreading|focal adhesion assembly|protein localization to membrane|,"phosphatidylinositol-3,4,5-trisphosphate binding|lipid binding|",10,0.3,1.92,10,0,0,0.2,0.33,0.33,0.807,0,0,-0.9,1.8
ENSMUSG00000022365,DERL1,"Der1-like domain family, member 1",Hrd1p ubiquitin ligase complex|early endosome|late endosome|endoplasmic reticulum|endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,"transport|response to unfolded protein|protein transport|ER-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum unfolded protein response|retrograde protein transport, ER to cytosol|cellular response to unfolded protein|",protein binding|MHC class I protein binding|,10,0.1,0.238,10,0.1,0.12,0.1,0.327,0.327,0.808,0,0,-0.8,1.9
ENSMUSG00000029718,PCOLCE,procollagen C-endopeptidase enhancer protein,extracellular region|collagen trimer|extracellular space|extracellular matrix|extracellular vesicular exosome|,proteolysis|positive regulation of peptidase activity|,collagen binding|heparin binding|peptidase activator activity|,10,-0.1,0.218,10,-0.1,0.139,-0.1,0.326,-0.326,0.809,0,0,-1.5,1.3
ENSMUSG00000042743,SGTB,"small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta",cellular_component|,biological_process|,protein homodimerization activity|protein heterodimerization activity|,10,0.3,1.9,10,-0.1,0.39,0.2,0.323,0.323,0.809,0,0,-1,1.7
ENSMUSG00000005045,CHD5,chromodomain helicase DNA binding protein 5,chromatin|heterochromatin|nucleus|nucleus|membrane|NuRD complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|spermatogenesis|nervous system development|negative regulation of cell proliferation|chromatin modification|cerebral cortex neuron differentiation|cell differentiation|spermatogenesis, exchange of chromosomal proteins|histone H4 acetylation|regulation of cell differentiation|regulation of transcription involved in cell fate commitment|regulation of transcription involved in cell fate commitment|histone H3-K27 trimethylation|positive regulation of signal transduction by p53 class mediator|","nucleotide binding|nucleic acid binding|DNA binding|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|histone deacetylase binding|metal ion binding|H3K27me3 modified histone binding|H3K27me3 modified histone binding|",10,-0.7,2.48,10,0.3,1.05,0.1,0.315,0.315,0.811,0,0,-1.9,1.1
ENSMUSG00000022665,CCDC80,coiled-coil domain containing 80,extracellular region|proteinaceous extracellular matrix|basement membrane|interstitial matrix|extracellular matrix|,positive regulation of cell-substrate adhesion|extracellular matrix organization|,fibronectin binding|glycosaminoglycan binding|heparin binding|,10,0,0,10,-0.4,2.42,-0.4,0.314,-0.314,0.812,0,0,-1.8,1.3
ENSMUSG00000051314,FFAR2,free fatty acid receptor 2,plasma membrane|plasma membrane|membrane|integral component of membrane|cell projection|,leukocyte chemotaxis involved in inflammatory response|regulation of acute inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|glucose homeostasis|cellular response to fatty acid|cellular response to fatty acid|regulation of peptide hormone secretion|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|lipid binding|,10,-0.2,0.894,10,0.4,1.17,0.2,0.314,0.314,0.812,0,0,-1,1.7
ENSMUSG00000041556,FBXO2,F-box protein 2,cytoplasm|endoplasmic reticulum|cytosol|cytosol|membrane|SCF ubiquitin ligase complex|dendritic spine|intracellular membrane-bounded organelle|extracellular vesicular exosome|,ubiquitin-dependent protein catabolic process|glycoprotein catabolic process|negative regulation of cell proliferation|protein ubiquitination|ER-associated ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|regulation of protein ubiquitination|,beta-amyloid binding|glycoprotein binding|protein binding|carbohydrate binding|,10,0.4,1.35,10,-0.2,0.178,0.1,0.312,0.312,0.812,0,0,-0.8,1.9
ENSMUSG00000048911,RNF24,ring finger protein 24,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.4,2.29,10,0.1,0.204,0.1,0.312,0.312,0.812,0,0,-1.1,1.9
ENSMUSG00000039686,ZER1,"zyg-11 related, cell cycle regulator",Cul2-RING ubiquitin ligase complex|,protein ubiquitination|regulation of ubiquitin-protein transferase activity|,ubiquitin-protein transferase activity|,10,0,0,10,-0.2,1.64,-0.1,0.307,-0.307,0.814,0,0,-1.5,1.3
ENSMUSG00000014547,WDFY2,WD repeat and FYVE domain containing 2,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.3,1.26,10,0,0,0.1,0.3,0.3,0.816,0,0,-1,1.8
ENSMUSG00000026171,RNF25,ring finger protein 25,nucleus|cytosol|,protein ubiquitination|positive regulation of NF-kappaB transcription factor activity|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|NF-kappaB binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.67,10,-0.1,0.0896,-0.1,0.297,-0.297,0.817,0,0,-1.4,1.4
ENSMUSG00000033721,VAV3,vav 3 oncogene,intracellular|cytoplasm|plasma membrane|extracellular vesicular exosome|,angiogenesis|vesicle fusion|cellular response to DNA damage stimulus|integrin-mediated signaling pathway|small GTPase mediated signal transduction|cell migration|cell projection assembly|lamellipodium assembly|neutrophil chemotaxis|positive regulation of B cell proliferation|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|response to drug|regulation of GTPase activity|positive regulation of GTPase activity|positive regulation of GTPase activity|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of cell adhesion|B cell receptor signaling pathway|,guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|epidermal growth factor receptor binding|protein binding|Rac guanyl-nucleotide exchange factor activity|metal ion binding|,10,0.3,0.685,10,0,0,0.1,0.296,0.296,0.817,0,0,-1.2,1.5
ENSMUSG00000058655,EIF4B,eukaryotic translation initiation factor 4B,None,translation|translational initiation|,nucleotide binding|nucleic acid binding|RNA binding|translation initiation factor activity|poly(A) RNA binding|,10,0,0,10,-0.3,0.61,-0.2,0.292,-0.292,0.818,0,0,-1.6,1.1
ENSMUSG00000028164,MANBA,"mannosidase, beta A, lysosomal",lysosome|lysosome|intracellular membrane-bounded organelle|,carbohydrate metabolic process|glycoprotein catabolic process|metabolic process|mannan catabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-mannosidase activity|beta-mannosidase activity|mannose binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,-0.1,0.121,10,0.2,0.602,0.1,0.291,0.291,0.818,0,0,-1.5,1.3
ENSMUSG00000044224,DNAJC21,"DnaJ (Hsp40) homolog, subfamily C, member 21",cellular_component|,biological_process|,poly(A) RNA binding|,10,0.8,3.13,10,0,0,0.8,0.289,0.289,0.819,0,0,-0.5,2
ENSMUSG00000056144,TRIM34A,tripartite motif-containing 34A,intracellular|,None,zinc ion binding|metal ion binding|,8,-0.1,0.307,9,1,1.52,-0.1,0.285,-0.285,0.82,0,0,-1.3,2
ENSMUSG00000044594,SERPINB3A,"serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A",extracellular region|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|enzyme binding|,10,0,0,10,0.2,0.589,0.1,0.283,0.283,0.821,0,0,-0.9,1.9
ENSMUSG00000073400,TRIM10,tripartite motif-containing 10,intracellular|cytoplasm|,erythrocyte differentiation|innate immune response|negative regulation of viral entry into host cell|,protein binding|zinc ion binding|metal ion binding|,10,-0.2,1.13,10,0.3,1.37,0.2,0.274,0.274,0.823,0,0,-1.2,1.6
ENSMUSG00000034684,SEMA3F,"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F",extracellular region|membrane|,neural crest cell migration|multicellular organismal development|axon guidance|axon guidance|nerve development|negative regulation of axon extension involved in axon guidance|negative regulation of axon extension involved in axon guidance|axon extension involved in axon guidance|negative chemotaxis|negative chemotaxis|negative chemotaxis|sympathetic ganglion development|sympathetic neuron projection extension|sympathetic neuron projection guidance|semaphorin-plexin signaling pathway involved in neuron projection guidance|,receptor activity|chemorepellent activity|chemorepellent activity|,10,0,0,10,0.1,0.343,0.1,0.273,0.273,0.823,0,0,-1,1.8
ENSMUSG00000041231,UBLCP1,ubiquitin-like domain containing CTD phosphatase 1,nucleus|nucleolus|,biological_process|,molecular_function|phosphoprotein phosphatase activity|hydrolase activity|,10,0.1,0.227,10,-0.4,1.58,0.1,0.272,0.272,0.824,0,0,-1.7,1.1
ENSMUSG00000052955,CPVL,"carboxypeptidase, vitellogenic-like",extracellular vesicular exosome|,proteolysis|,carboxypeptidase activity|serine-type carboxypeptidase activity|peptidase activity|hydrolase activity|,10,0.3,0.385,10,-0.2,0.782,-0.1,0.27,-0.27,0.824,0,0,-1.3,1.5
ENSMUSG00000021770,SAMD8,sterile alpha motif domain containing 8,endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,lipid metabolic process|sphingolipid metabolic process|sphingomyelin biosynthetic process|ceramide biosynthetic process|regulation of ceramide biosynthetic process|,molecular_function|cardiolipin synthase activity|transferase activity|UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity|GDP-mannose:serine-protein mannose-1-phosphotransferase activity|archaetidylserine synthase activity|,10,0,0,10,-0.2,0.712,-0.1,0.268,-0.268,0.825,0,0,-1.5,1.3
ENSMUSG00000041984,RPTN,repetin,cornified envelope|extracellular region|proteinaceous extracellular matrix|,None,calcium ion binding|metal ion binding|,10,-0.3,0.745,10,0,0,-0.1,0.268,-0.268,0.825,0,0,-1.8,1
ENSMUSG00000064225,PAQR9,progestin and adipoQ receptor family member IX,cellular_component|membrane|integral component of membrane|,biological_process|,receptor activity|,10,-0.1,0.276,10,-0.1,0.0168,-0.1,0.268,-0.268,0.825,0,0,-1.7,1.2
ENSMUSG00000039904,GPR37,G protein-coupled receptor 37,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|locomotion involved in locomotory behavior|dopamine biosynthetic process|positive regulation of dopamine metabolic process|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0.2,0.692,0.1,0.264,0.264,0.826,0,0,-1.2,1.7
ENSMUSG00000007783,CPT1C,carnitine palmitoyltransferase 1c,mitochondrion|mitochondrial outer membrane|endoplasmic reticulum membrane|membrane|integral component of membrane|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|,lipid metabolic process|fatty acid metabolic process|carnitine metabolic process|,"carnitine O-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.3,2.24,10,0,0,0.2,0.262,0.262,0.826,0,0,-0.9,1.7
ENSMUSG00000032547,RYK,receptor-like tyrosine kinase,nucleus|cytoplasm|plasma membrane|membrane|integral component of membrane|,protein phosphorylation|signal transduction|axonogenesis|axon guidance|axon guidance|Wnt signaling pathway|Wnt signaling pathway|phosphorylation|corpus callosum development|neuron differentiation|neuron projection development|positive regulation of MAPK cascade|skeletal system morphogenesis|negative regulation of axon extension involved in axon guidance|negative chemotaxis|commissural neuron axon guidance|,"nucleotide binding|protein kinase activity|transmembrane receptor protein tyrosine kinase activity|transmembrane signaling receptor activity|frizzled binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Wnt-protein binding|Wnt-activated receptor activity|",10,-0.2,0.825,10,0,0,-0.1,0.262,-0.262,0.826,0,0,-1,1.8
ENSMUSG00000044308,UBR3,ubiquitin protein ligase E3 component n-recognin 3,cellular_component|membrane|integral component of membrane|,in utero embryonic development|suckling behavior|ubiquitin-dependent protein catabolic process|sensory perception of smell|embryo development|protein ubiquitination|olfactory behavior|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.0146,10,-0.2,0.284,-0.1,0.261,-0.261,0.827,0,0,-1.6,1.2
ENSMUSG00000004931,APBA3,"amyloid beta (A4) precursor protein-binding, family A, member 3",cytoplasm|perinuclear region of cytoplasm|,in utero embryonic development|transport|synaptic transmission|regulation of gene expression|protein transport|negative regulation of catalytic activity|,beta-amyloid binding|enzyme inhibitor activity|enzyme binding|,10,-0.1,0.147,10,0.2,0.23,-0.1,0.259,-0.259,0.827,0,0,-1.6,1.3
ENSMUSG00000021978,EXTL3,exostoses (multiple)-like 3,endoplasmic reticulum|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|,heparan sulfate proteoglycan biosynthetic process|positive regulation of cell growth|,"glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|metal ion binding|",10,-0.6,2.58,10,0.1,0.189,-0.4,0.257,-0.257,0.827,0,0,-2,0.6
ENSMUSG00000042215,BAG2,BCL2-associated athanogene 2,cellular_component|,protein metabolic process|,molecular_function|chaperone binding|,10,0.3,1.52,10,-0.3,1.52,0.1,0.257,0.257,0.827,0,0,-1.3,1.4
ENSMUSG00000021573,TPPP,tubulin polymerization promoting protein,nucleus|nucleus|cytoplasm|cytoplasm|cytoskeleton|microtubule|microtubule|perinuclear region of cytoplasm|,microtubule bundle formation|positive regulation of protein polymerization|microtubule polymerization|microtubule polymerization|,tubulin binding|,10,0.1,0.324,10,0,0,0.1,0.253,0.253,0.829,0,0,-1.2,1.7
ENSMUSG00000026042,COL5A2,"collagen, type V, alpha 2",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type V trimer|,skeletal system development|collagen fibril organization|collagen fibril organization|skin development|skin development|eye morphogenesis|cellular response to amino acid stimulus|,extracellular matrix structural constituent|SMAD binding|metal ion binding|,10,-0.2,0.983,10,0,0,-0.1,0.252,-0.252,0.829,0,0,-1.7,1.2
ENSMUSG00000038295,ATG9B,autophagy related 9B,pre-autophagosomal structure|cytoplasm|autophagic vacuole|membrane|integral component of membrane|cytoplasmic vesicle|,autophagic vacuole assembly|autophagic vacuole assembly|mitochondrion degradation|autophagy|protein localization to pre-autophagosomal structure|piecemeal microautophagy of nucleus|late nucleophagy|,molecular_function|,10,0,0,10,-0.1,0.332,-0.1,0.251,-0.251,0.829,0,0,-1.2,1.7
ENSMUSG00000051984,SEC31B,Sec31 homolog B (S. cerevisiae),cytoplasm|endoplasmic reticulum|membrane|vesicle coat|cytoplasmic vesicle|,transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|,10,0.2,0.407,10,-0.1,0.381,-0.1,0.25,-0.25,0.829,0,0,-1.5,1.4
ENSMUSG00000029130,RNF32,ring finger protein 32,cytoplasm|endosome|aggresome|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.3,0.659,10,0,0,-0.1,0.249,-0.249,0.83,0,0,-1.9,0.8
ENSMUSG00000050711,SCG2,secretogranin II,extracellular region|extracellular space|intracellular|secretory granule|,MAPK cascade|MAPK cascade|angiogenesis|angiogenesis|positive regulation of endothelial cell proliferation|cellular component movement|intracellular signal transduction|eosinophil chemotaxis|positive chemotaxis|induction of positive chemotaxis|negative regulation of endothelial cell apoptotic process|negative regulation of extrinsic apoptotic signaling pathway|,cytokine activity|cytokine activity|chemoattractant activity|,10,0,0,10,-0.3,1.28,-0.2,0.247,-0.247,0.83,0,0,-1.4,1.6
ENSMUSG00000043279,TRIM56,tripartite motif-containing 56,intracellular|cytoplasm|,immune system process|interferon-beta production|response to type I interferon|innate immune response|negative regulation of viral entry into host cell|defense response to virus|protein K63-linked ubiquitination|negative regulation of viral release from host cell|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.0585,10,-0.2,0.211,-0.1,0.238,-0.238,0.833,0,0,-1.6,1.2
ENSMUSG00000052013,BTLA,B and T lymphocyte associated,integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,immune system process|immune response-regulating cell surface receptor signaling pathway|cell surface receptor signaling pathway|negative regulation of B cell proliferation|negative regulation of T cell proliferation|negative regulation of alpha-beta T cell proliferation|,receptor activity|protein binding|,10,0,0,10,0.1,0.378,0.1,0.237,0.237,0.833,0,0,-1.3,1.6
ENSMUSG00000043251,EXOC3L,exocyst complex component 3-like,exocyst|secretory granule|cytoplasmic vesicle|,exocytosis|peptide hormone secretion|,protein binding|,10,0.2,1.45,10,-0.1,0.0881,0.2,0.235,0.235,0.834,0,0,-1.5,1.4
ENSMUSG00000069733,UBE2U,ubiquitin-conjugating enzyme E2U (putative),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.8,2.1,0.1,0.23,0.23,0.835,0,0,-0.5,2
ENSMUSG00000054414,SLC30A7,"solute carrier family 30 (zinc transporter), member 7",cytoplasm|cytoplasm|Golgi apparatus|Golgi apparatus|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|vesicle|perinuclear region of cytoplasm|extracellular vesicular exosome|,transport|ion transport|cation transport|zinc ion transport|transmembrane transport|,zinc ion binding|cation transmembrane transporter activity|,10,0,0,10,0.6,1.24,0.1,0.229,0.229,0.835,0,0,-0.9,2
ENSMUSG00000018395,KIF3A,kinesin family member 3A,cytoplasm|centrosome|cytoskeleton|kinesin complex|microtubule|spindle microtubule|cilium|axoneme|synaptic vesicle|microtubule cytoskeleton|kinesin II complex|kinesin II complex|intraciliary transport particle|photoreceptor connecting cilium|cell projection|neuron projection|extracellular vesicular exosome|primary cilium|,in utero embryonic development|kidney development|microtubule-based movement|smoothened signaling pathway|determination of left/right symmetry|heart development|epidermis development|anterior/posterior pattern specification|dorsal/ventral pattern formation|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|cell projection organization|epidermal stem cell homeostasis|cilium assembly|positive regulation of receptor-mediated endocytosis|positive regulation of epithelial cell proliferation|inner ear receptor stereocilium organization|cilium morphogenesis|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|spectrin binding|protein complex binding|,10,0.2,0.581,10,0,0,0.1,0.227,0.227,0.836,0,0,-1.4,1.5
ENSMUSG00000054978,KBTBD13,kelch repeat and BTB (POZ) domain containing 13,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.1,0.00181,10,0.1,0.243,0.1,0.224,0.224,0.837,0,0,-1,1.8
ENSMUSG00000029592,USP30,ubiquitin specific peptidase 30,mitochondrion|mitochondrial outer membrane|mitochondrial outer membrane|membrane|integral component of membrane|,mitochondrion degradation|proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|,cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0,0,10,0.8,1.92,0.1,0.223,0.223,0.837,0,0,-0.7,2
ENSMUSG00000024963,DNAJC4,"DnaJ (Hsp40) homolog, subfamily C, member 4",mitochondrion|membrane|integral component of membrane|,None,None,10,-0.1,0.346,10,0,0,-0.1,0.222,-0.222,0.837,0,0,-1.8,1.1
ENSMUSG00000001021,S100A3,S100 calcium binding protein A3,nucleolus|cytoplasm|,None,calcium ion binding|zinc ion binding|metal ion binding|,10,-0.3,0.707,10,0,0,-0.1,0.221,-0.221,0.838,0,0,-1.7,1.2
ENSMUSG00000022124,FBXL3,F-box and leucine-rich repeat protein 3,nucleus|nucleus|cytoplasm|cytosol|SCF ubiquitin ligase complex|,protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|protein destabilization|regulation of circadian rhythm|regulation of circadian rhythm|entrainment of circadian clock by photoperiod|proteasome-mediated ubiquitin-dependent protein catabolic process|rhythmic process|,ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|,10,0.4,1.63,10,0,0,0.1,0.219,0.219,0.838,0,0,-0.9,1.8
ENSMUSG00000089687,RAB42,"RAB42, member RAS oncogene family",cellular_component|,biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0.1,0.166,10,-0.2,0.0904,0.1,0.217,0.217,0.839,0,0,-1.3,1.6
ENSMUSG00000067299,CRYGD,"crystallin, gamma D",nucleus|cytoplasm|,eye development|lens development in camera-type eye|visual perception|cellular response to reactive oxygen species|lens fiber cell differentiation|lens fiber cell differentiation|,structural constituent of eye lens|structural constituent of eye lens|,10,-0.2,0.71,10,0,0,-0.1,0.214,-0.214,0.84,0,0,-1.7,1.2
ENSMUSG00000054580,PLA2R1,phospholipase A2 receptor 1,extracellular region|plasma membrane|cell surface|membrane|integral component of membrane|receptor complex|extracellular vesicular exosome|,"cytokine production|endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|positive regulation of DNA damage response, signal transduction by p53 class mediator|reactive oxygen species metabolic process|positive regulation of arachidonic acid secretion|replicative senescence|oxidative stress-induced premature senescence|negative regulation of phospholipase A2 activity|negative regulation of arachidonic acid secretion|",receptor activity|receptor activity|carbohydrate binding|phospholipase binding|phospholipase binding|,10,0.2,0.421,10,-0.2,0.484,-0.1,0.21,-0.21,0.841,0,0,-1.2,1.7
ENSMUSG00000029368,ALB,albumin,extracellular region|basement membrane|extracellular space|extracellular space|nucleus|cytoplasm|protein complex|extracellular vesicular exosome|blood microparticle|,"transport|cellular response to starvation|hemolysis by symbiont of host erythrocytes|negative regulation of apoptotic process|positive regulation of circadian sleep/wake cycle, non-REM sleep|maintenance of mitochondrion location|",DNA binding|fatty acid binding|drug binding|zinc ion binding|lipid binding|toxic substance binding|oxygen binding|enzyme binding|pyridoxal phosphate binding|metal ion binding|chaperone binding|,10,0.4,1.01,10,-0.1,0.491,0.1,0.209,0.209,0.841,0,0,-1.1,1.7
ENSMUSG00000034781,GNA11,"guanine nucleotide binding protein, alpha 11",cytoplasm|lysosomal membrane|cytosol|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|plasma membrane|membrane|protein complex|extracellular vesicular exosome|,skeletal system development|action potential|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|heart development|regulation of melanocyte differentiation|developmental pigmentation|phospholipase C-activating dopamine receptor signaling pathway|cellular response to pH|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|GTPase activity|signal transducer activity|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|type 2A serotonin receptor binding|type 2A serotonin receptor binding|protein complex binding|metal ion binding|,10,0,0,10,-0.2,0.851,-0.1,0.208,-0.208,0.841,0,0,-1.6,1.2
ENSMUSG00000053898,ECH1,"enoyl coenzyme A hydratase 1, peroxisomal",mitochondrion|mitochondrion|peroxisome|membrane|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|metabolic process|,"C-8 sterol isomerase activity|catalytic activity|receptor binding|delta5-delta2,4-dienoyl-CoA isomerase activity|isomerase activity|3-carboxymuconate cycloisomerase type II activity|",10,0.1,0.156,10,-0.2,0.832,-0.1,0.207,-0.207,0.842,0,0,-1.2,1.7
ENSMUSG00000000753,SERPINF1,"serine (or cysteine) peptidase inhibitor, clade F, member 1",extracellular region|extracellular region|basement membrane|extracellular space|extracellular space|axon|extracellular matrix|neuronal cell body|axon hillock|perinuclear region of cytoplasm|extracellular vesicular exosome|,short-term memory|negative regulation of endothelial cell migration|negative regulation of gene expression|negative regulation of endopeptidase activity|positive regulation of neuron projection development|negative regulation of angiogenesis|negative regulation of angiogenesis|regulation of proteolysis|negative regulation of inflammatory response|positive regulation of neurogenesis|negative regulation of epithelial cell proliferation involved in prostate gland development|negative regulation of neuron death|,serine-type endopeptidase inhibitor activity|,10,0.1,0.0113,10,-0.1,0.259,-0.1,0.205,-0.205,0.842,0,0,-1.7,1.2
ENSMUSG00000041740,RNF10,ring finger protein 10,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of Schwann cell proliferation|positive regulation of myelination|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|protein autoubiquitination|",DNA binding|ubiquitin-protein transferase activity|zinc ion binding|transcription regulatory region DNA binding|metal ion binding|,10,0.1,0.0644,10,-0.1,0.346,0.1,0.204,0.204,0.842,0,0,-1.7,1.1
ENSMUSG00000047746,FBXO40,F-box protein 40,cytoplasm|,biological_process|protein ubiquitination|,ubiquitin-protein transferase activity|zinc ion binding|metal ion binding|,10,0.2,0.842,10,0,0,0.1,0.203,0.203,0.843,0,0,-1,1.8
ENSMUSG00000023070,RGN,regucalcin,nucleus|cytoplasm|,cellular calcium ion homeostasis|L-ascorbic acid biosynthetic process|positive regulation of ATPase activity|regulation of calcium-mediated signaling|,gluconolactonase activity|gluconolactonase activity|calcium ion binding|zinc ion binding|hydrolase activity|enzyme regulator activity|metal ion binding|,10,0,0,10,0.1,0.262,0.1,0.202,0.202,0.843,0,0,-1.5,1.3
ENSMUSG00000036180,GATAD2A,GATA zinc finger domain containing 2A,nucleus|NuRD complex|,"blood vessel development|in utero embryonic development|neural fold formation|transcription, DNA-templated|regulation of transcription, DNA-templated|embryonic body morphogenesis|programmed cell death|anterior neuropore closure|negative regulation of transcription, DNA-templated|","protein binding, bridging|metal ion binding|",10,0,0,10,0.5,0.945,0.1,0.201,0.201,0.843,0,0,-0.4,2
ENSMUSG00000025937,LACTB2,"lactamase, beta 2",mitochondrion|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|metal ion binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0.1,0.442,10,0,0,0.1,0.193,0.193,0.846,0,0,-1.1,1.8
ENSMUSG00000054792,KLHL18,kelch-like 18,cellular_component|,biological_process|,molecular_function|,10,0.3,1.23,10,0,0,0.1,0.193,0.193,0.846,0,0,-0.9,1.9
ENSMUSG00000096054,SYNE1,"spectrin repeat containing, nuclear envelope 1",cell|nucleus|nuclear envelope|nuclear envelope|nuclear envelope|cytoplasm|Golgi apparatus|spindle|cytoskeleton|membrane|integral component of membrane|sarcomere|midbody|nuclear membrane|SUN-KASH complex|dendritic spine|postsynaptic membrane|perinuclear region of cytoplasm|,Golgi organization|establishment of nucleus localization|muscle cell differentiation|positive regulation of receptor-mediated endocytosis|regulation of dendrite morphogenesis|cytoskeletal anchoring at nuclear membrane|nuclear matrix anchoring at nuclear membrane|,actin binding|receptor binding|protein binding|lamin binding|enzyme binding|protein homodimerization activity|poly(A) RNA binding|actin filament binding|,10,0.2,0.558,10,-0.2,1.02,-0.1,0.192,-0.192,0.846,0,0,-1.8,1.1
ENSMUSG00000030688,STARD10,START domain containing 10,cytoplasm|cytosol|microvillus|cilium|membrane|cell projection|intercellular canaliculus|,transport|lipid transport|bile acid secretion|positive regulation of peroxisome proliferator activated receptor signaling pathway|,lipid binding|,10,-0.2,1.03,10,1.1,1.83,-0.1,0.192,-0.192,0.846,0,0,-0.9,2
ENSMUSG00000075031,HIST1H2BB,"histone cluster 1, H2bb",nucleosome|nucleus|chromosome|,None,DNA binding|protein heterodimerization activity|,8,0.3,1.03,8,-0.2,0.347,-0.1,0.191,-0.191,0.846,0,0,-1.4,1.6
ENSMUSG00000049285,MBLAC1,metallo-beta-lactamase domain containing 1,cellular_component|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|metal ion binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.1,0.477,10,0,0,-0.1,0.187,-0.187,0.848,0,0,-1.1,1.8
ENSMUSG00000024245,TMEM178,transmembrane protein 178,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.17,10,0,0,0.1,0.181,0.181,0.849,0,0,-1.6,1.2
ENSMUSG00000045287,RTN4RL1,reticulon 4 receptor-like 1,plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|anchored component of membrane|membrane raft|anchored component of plasma membrane|,axon regeneration|,receptor activity|,10,-0.1,0.267,10,-0.9,0.809,-0.1,0.178,-0.178,0.85,0,0,-2,1
ENSMUSG00000042286,STAB1,stabilin 1,cytoplasm|integral component of plasma membrane|membrane|integral component of membrane|,receptor-mediated endocytosis|inflammatory response|cell adhesion|cell-cell signaling|negative regulation of angiogenesis|defense response to bacterium|,low-density lipoprotein receptor activity|scavenger receptor activity|hyaluronic acid binding|low-density lipoprotein particle binding|,10,-0.1,0.294,10,0,0,-0.1,0.177,-0.177,0.85,0,0,-1.6,1.3
ENSMUSG00000001379,APBB3,"amyloid beta (A4) precursor protein-binding, family B, member 3",cytoplasm|actin cytoskeleton|,negative regulation of apoptotic process|,beta-amyloid binding|,9,-0.1,0.0649,9,-1.1,2.56,0.1,0.176,0.176,0.851,0,0,-2,0.8
ENSMUSG00000020707,RNF135,ring finger protein 135,cytoplasm|,immune system process|protein ubiquitination|positive regulation of interferon-beta production|innate immune response|regulation of innate immune response|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ribonucleoprotein complex binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.1,0.263,0.1,0.174,0.174,0.851,0,0,-1.1,1.8
ENSMUSG00000031024,ST5,suppression of tumorigenicity 5,cellular_component|,positive regulation of Rab GTPase activity|positive regulation of ERK1 and ERK2 cascade|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.1,0.169,10,-0.1,0.0226,-0.1,0.174,-0.174,0.851,0,0,-1.1,2
ENSMUSG00000052384,NRROS,negative regulator of reactive oxygen species,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,immune system process|superoxide metabolic process|inflammatory response|immune response|ER-associated ubiquitin-dependent protein catabolic process|innate immune response|,protein binding|,10,0.1,0.0442,10,-0.1,0.317,-0.1,0.172,-0.172,0.852,0,0,-1.3,1.5
ENSMUSG00000037606,OSBPL5,oxysterol binding protein-like 5,endoplasmic reticulum|membrane|membrane|integral component of membrane|,transport|lipid transport|,lipid binding|cholesterol binding|,10,-0.2,0.76,10,0.3,1.17,-0.1,0.171,-0.171,0.852,0,0,-1.2,1.6
ENSMUSG00000073079,SRP54A,signal recognition particle 54A,"nucleus|cytoplasm|signal recognition particle, endoplasmic reticulum targeting|",SRP-dependent cotranslational protein targeting to membrane|,GTPase activity|GTP binding|drug binding|7S RNA binding|GDP binding|endoplasmic reticulum signal peptide binding|ribonucleoprotein complex binding|poly(A) RNA binding|,0,0,0,1,-0.2,0.187,-0.2,0.171,-0.171,0.852,0,0,-2,1.8
ENSMUSG00000044312,NEUROG3,neurogenin 3,intracellular|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|cell differentiation|epithelial cell differentiation|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of dendrite morphogenesis|positive regulation of sequence-specific DNA binding transcription factor activity|transdifferentiation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|core promoter binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|chromatin DNA binding|protein dimerization activity|,10,0.4,1.03,10,-0.1,0.253,0.2,0.167,0.167,0.853,0,0,-1.1,1.7
ENSMUSG00000031375,BGN,biglycan,extracellular region|proteinaceous extracellular matrix|intracellular|cell surface|transport vesicle|extracellular matrix|extracellular matrix|sarcolemma|extracellular vesicular exosome|,peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|,glycosaminoglycan binding|extracellular matrix binding|,9,0,0,9,-0.2,0.337,-0.1,0.165,-0.165,0.853,0,0,-1.5,1.5
ENSMUSG00000022556,HSF1,heat shock factor 1,nucleus|nucleus|cytoplasm|cytoplasm|protein complex|pronucleus|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein phosphorylation|response to stress|defense response|female meiotic division|spermatogenesis|negative regulation of cell proliferation|response to heat|response to lipopolysaccharide|negative regulation of tumor necrosis factor production|cellular response to heat|positive regulation of multicellular organism growth|positive regulation of transcription from RNA polymerase II promoter|embryonic process involved in female pregnancy|regulation of spindle checkpoint|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.2,0.504,0.1,0.163,0.163,0.854,0,0,-0.7,2
ENSMUSG00000022500,LITAF,LPS-induced TN factor,nucleus|cytoplasm|lysosome|lysosomal membrane|Golgi apparatus|plasma membrane|membrane|intracellular membrane-bounded organelle|,"regulation of cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|signal transduction|response to lipopolysaccharide|negative regulation of NF-kappaB import into nucleus|positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular response to lipopolysaccharide|",signal transducer activity|protein binding|WW domain binding|,10,0,0,10,-0.2,1.17,-0.1,0.163,-0.163,0.854,0,0,-1.7,1.2
ENSMUSG00000030839,SERGEF,secretion regulating guanine nucleotide exchange factor,nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|intermediate filament cytoskeleton|,positive regulation of Ran GTPase activity|negative regulation of protein secretion|,guanyl-nucleotide exchange factor activity|Ran guanyl-nucleotide exchange factor activity|,10,0.2,0.28,10,0,0,0.1,0.162,0.162,0.854,0,0,-1.3,1.6
ENSMUSG00000021143,PACS2,phosphofurin acidic cluster sorting protein 2,mitochondrion|endoplasmic reticulum|,autophagic vacuole assembly|apoptotic process|protein localization to pre-autophagosomal structure|protein targeting to plasma membrane|,None,10,0.1,0.067,10,0.1,0.111,0.1,0.162,0.162,0.854,0,0,-1.1,1.8
ENSMUSG00000031483,ERLIN2,ER lipid raft associated 2,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|protein complex|extracellular vesicular exosome|,ER-associated ubiquitin-dependent protein catabolic process|,protein binding|,10,-0.1,0.611,10,0,0,-0.1,0.158,-0.158,0.855,0,0,-1.7,1.2
ENSMUSG00000078786,BC024978,cDNA sequence BC024978,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.4,1.3,-0.1,0.157,-0.157,0.856,0,0,-1.7,1.1
ENSMUSG00000033287,KCTD17,potassium channel tetramerisation domain containing 17,cellular_component|,biological_process|,identical protein binding|,10,0.3,0.989,10,-0.1,0.0661,0.2,0.156,0.156,0.856,0,0,-1,1.8
ENSMUSG00000005681,APOA2,apolipoprotein A-II,extracellular region|extracellular space|very-low-density lipoprotein particle|high-density lipoprotein particle|spherical high-density lipoprotein particle|chylomicron|extracellular vesicular exosome|blood microparticle|,negative regulation of cytokine secretion involved in immune response|protein folding|fatty acid metabolic process|phosphatidylcholine biosynthetic process|transport|lipid transport|cholesterol metabolic process|cholesterol metabolic process|phospholipid catabolic process|response to glucose|positive regulation of cholesterol esterification|negative regulation of very-low-density lipoprotein particle remodeling|beta-glucoside transport|protein oxidation|peptidyl-methionine modification|regulation of intestinal cholesterol absorption|cholesterol transport|organ regeneration|regulation of protein stability|negative regulation of cholesterol transport|cholesterol efflux|phospholipid efflux|triglyceride-rich lipoprotein particle remodeling|low-density lipoprotein particle remodeling|high-density lipoprotein particle remodeling|high-density lipoprotein particle assembly|high-density lipoprotein particle clearance|lipoprotein metabolic process|cholesterol homeostasis|cholesterol homeostasis|cholesterol homeostasis|cholesterol homeostasis|positive regulation of catalytic activity|reverse cholesterol transport|positive regulation of interleukin-8 biosynthetic process|diacylglycerol catabolic process|negative regulation of lipid catabolic process|positive regulation of lipid catabolic process|negative regulation of lipase activity|negative regulation of lipase activity|negative regulation of cholesterol import|negative regulation of cholesterol transporter activity|,lipid transporter activity|phospholipid binding|high-density lipoprotein particle binding|lipid binding|cholesterol binding|cholesterol transporter activity|cholesterol transporter activity|phosphatidylcholine binding|apolipoprotein receptor binding|protein homodimerization activity|protein heterodimerization activity|lipase inhibitor activity|phosphatidylcholine-sterol O-acyltransferase activator activity|high-density lipoprotein particle receptor binding|,10,-0.1,0.285,10,0.1,0.114,0.1,0.153,0.153,0.857,0,0,-1.4,1.5
ENSMUSG00000003344,BTBD2,BTB (POZ) domain containing 2,cytoplasmic mRNA processing body|cytoplasmic mRNA processing body|,biological_process|,protein binding|,10,0,0,10,-0.2,0.653,-0.1,0.152,-0.152,0.857,0,0,-1.3,1.6
ENSMUSG00000026691,FMO3,flavin containing monooxygenase 3,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,drug metabolic process|oxidation-reduction process|,"monooxygenase activity|N,N-dimethylaniline monooxygenase activity|oxidoreductase activity|amino acid binding|trimethylamine monooxygenase activity|flavin adenine dinucleotide binding|NADP binding|",10,0,0,10,-0.2,0.582,-0.1,0.149,-0.149,0.858,0,0,-1.7,1.2
ENSMUSG00000048400,PRSS54,"protease, serine 54",extracellular region|cytoplasm|,proteolysis|biological_process|,molecular_function|catalytic activity|serine-type endopeptidase activity|,10,0,0,10,-0.1,0.171,-0.1,0.146,-0.146,0.859,0,0,-1.6,1.3
ENSMUSG00000047026,ACSM4,acyl-CoA synthetase medium-chain family member 4,mitochondrion|mitochondrion|,lipid metabolic process|fatty acid metabolic process|acyl-CoA metabolic process|metabolic process|,nucleotide binding|catalytic activity|fatty-acyl-CoA synthase activity|ATP binding|ligase activity|metal ion binding|butyrate-CoA ligase activity|,10,0.1,0.0773,10,0.1,0.0819,0.1,0.145,0.145,0.859,0,0,-1.3,1.5
ENSMUSG00000096807,HIST1H2BM,"histone cluster 1, H2bm",nucleosome|nucleus|chromosome|extracellular vesicular exosome|,None,DNA binding|protein heterodimerization activity|,8,0.9,1.57,7,0,0,0.1,0.14,0.14,0.86,0,0,-0.7,2
ENSMUSG00000069267,HIST1H3B,"histone cluster 1, H3b",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,None,5,0,0,5,0.5,1.02,0.4,0.14,0.14,0.86,0,0,-1.2,2
ENSMUSG00000075032,HIST1H3I,"histone cluster 1, H3i",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,molecular_function|,7,-0.4,0.395,7,-0.1,0.121,-0.2,0.139,-0.139,0.86,0,0,-2,1
ENSMUSG00000026421,CSRP1,cysteine and glycine-rich protein 1,nucleus|actin cytoskeleton|extracellular vesicular exosome|,actin cytoskeleton organization|,protein binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,-0.1,0.168,-0.1,0.139,-0.139,0.86,0,0,-1.5,1.4
ENSMUSG00000066071,CYP4A12A,"cytochrome P450, family 4, subfamily a, polypeptide 12a",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|alkane 1-monooxygenase activity|heme binding|metal ion binding|aromatase activity|",10,0,0,10,0.7,2.16,0.1,0.138,0.138,0.861,0,0,-1.6,1.8
ENSMUSG00000043421,HILPDA,hypoxia inducible lipid droplet associated,extracellular region|extracellular space|lipid particle|cell surface|membrane|integral component of membrane|secretory granule|,positive regulation of cytokine production|response to stress|positive regulation of cell proliferation|positive regulation of lipid storage|autocrine signaling|,receptor binding|,10,0.3,1.74,10,0,0,0.2,0.135,0.135,0.861,0,0,-1.2,1.6
ENSMUSG00000029076,SDF4,stromal cell derived factor 4,cytoplasm|late endosome|late endosome|Golgi apparatus|Golgi lumen|plasma membrane|membrane|extracellular vesicular exosome|,UV protection|UV protection|calcium ion-dependent exocytosis|cerebellum development|response to ethanol|zymogen granule exocytosis|,calcium ion binding|calcium ion binding|identical protein binding|metal ion binding|,10,-0.2,0.509,10,0,0,0.1,0.132,0.132,0.862,0,0,-1.4,1.4
ENSMUSG00000030255,SSPN,sarcospan,plasma membrane|membrane|integral component of membrane|cell junction|transport vesicle|sarcolemma|synapse|postsynaptic membrane|,None,None,10,-0.1,0.028,10,0.4,1.03,-0.1,0.132,-0.132,0.862,0,0,-1.1,1.8
ENSMUSG00000035211,XRRA1,X-ray radiation resistance associated 1,nucleus|cytoplasm|,response to X-ray|,molecular_function|,10,0.2,0.65,10,-0.1,0.482,-0.1,0.131,-0.131,0.863,0,0,-1.3,1.5
ENSMUSG00000018378,CUEDC1,CUE domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.105,10,-0.1,0.0363,-0.1,0.129,-0.129,0.863,0,0,-1.9,1
ENSMUSG00000027967,NEUROG2,neurogenin 2,nucleus|,"neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|axon guidance|central nervous system neuron development|central nervous system neuron development|neurogenesis|cell differentiation|neuron differentiation|forebrain development|cell fate commitment|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|positive regulation of sequence-specific DNA binding transcription factor activity|",DNA binding|protein binding|sequence-specific DNA binding|protein dimerization activity|E-box binding|,10,-0.1,0.389,10,0,0,-0.1,0.129,-0.129,0.863,0,0,-1.5,1.5
ENSMUSG00000037316,BAG4,BCL2-associated athanogene 4,nucleus|cytoplasm|cytosol|plasma membrane|,"apoptotic process|positive regulation of fibroblast migration|positive regulation of actin filament polymerization|positive regulation of peptidyl-serine phosphorylation|regulation of apoptotic process|positive regulation of cell adhesion|protein heterooligomerization|positive regulation of stress fiber assembly|positive regulation of protein kinase B signaling|cellular response to tumor necrosis factor|cellular response to epidermal growth factor stimulus|protein localization to plasma membrane|negative regulation of mRNA modification|ruffle assembly|negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity|",protein binding|poly(A) RNA binding|chaperone binding|,10,0,0,10,0.6,0.763,0.6,0.127,0.127,0.864,0,0,-0.6,2
ENSMUSG00000020319,WDPCP,WD repeat containing planar cell polarity effector,cytoplasm|cytoskeleton|plasma membrane|cilium|membrane|cell projection|axonemal basal plate|,kidney development|auditory receptor cell morphogenesis|smoothened signaling pathway|nervous system development|regulation of fibroblast migration|cell projection organization|cilium assembly|embryonic digit morphogenesis|camera-type eye development|cilium organization|establishment of protein localization|embryonic organ development|regulation of focal adhesion assembly|digestive system development|palate development|respiratory system development|cardiovascular system development|glomerular visceral epithelial cell migration|regulation of ruffle assembly|regulation of establishment of cell polarity|,protein binding|,10,0.2,0.504,10,0,0,0.1,0.123,0.123,0.865,0,0,-1.4,1.5
ENSMUSG00000048752,PRSS50,"protease, serine 50",cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,0,0,10,0.1,0.324,0.1,0.123,0.123,0.865,0,0,-1,1.8
ENSMUSG00000008167,FBXW9,F-box and WD-40 domain protein 9,cellular_component|,SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|,molecular_function|,10,-0.1,0.0969,10,0.2,0.894,0.1,0.122,0.122,0.865,0,0,-1.2,1.6
ENSMUSG00000036743,PSMA8,"proteasome (prosome, macropain) subunit, alpha type, 8","proteasome complex|nucleus|cytoplasm|proteasome core complex|proteasome core complex, alpha-subunit complex|spermatoproteasome complex|",proteolysis|ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,-0.5,2.43,10,0,0,0.1,0.122,0.122,0.865,0,0,-1.7,1.2
ENSMUSG00000078653,CNTD1,cyclin N-terminal domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.146,0.1,0.116,0.116,0.867,0,0,-1.6,1.2
ENSMUSG00000025006,SORBS1,sorbin and SH3 domain containing 1,stress fiber|nucleus|nucleus|cytoplasm|cytosol|cytoskeleton|plasma membrane|insulin receptor complex|cell-cell adherens junction|cell-substrate adherens junction|membrane|nuclear matrix|flotillin complex|cell junction|membrane raft|,transport|actin filament organization|insulin receptor signaling pathway|insulin receptor signaling pathway|positive regulation of signal transduction|glucose transport|cellular response to insulin stimulus|cellular response to insulin stimulus|stress fiber assembly|positive regulation of glycogen biosynthetic process|positive regulation of glucose import|positive regulation of lipid biosynthetic process|focal adhesion assembly|positive regulation of establishment of protein localization to plasma membrane|,SH3/SH2 adaptor activity|insulin receptor binding|insulin receptor binding|insulin receptor binding|protein binding|transcription factor binding|protein kinase binding|,10,-0.2,0.623,10,0,0,-0.1,0.102,-0.102,0.871,0,0,-1.4,1.5
ENSMUSG00000066652,LEFTY2,left-right determination factor 2,extracellular region|extracellular space|,multicellular organismal development|cell growth|growth|,cytokine activity|transforming growth factor beta receptor binding|growth factor activity|,10,0.3,0.794,10,-0.1,0.15,0.1,0.102,0.102,0.871,0,0,-1.3,1.6
ENSMUSG00000078627,10-Mar,membrane-associated ring finger (C3HC4) 10,cellular_component|,biological_process|,molecular_function|,10,0.8,2.1,10,0,0,0.2,0.0917,0.0917,0.874,0,0,-0.5,2
ENSMUSG00000020604,ARSG,arylsulfatase G,extracellular space|lysosome|endoplasmic reticulum|,sulfur compound metabolic process|metabolic process|,catalytic activity|sulfuric ester hydrolase activity|hydrolase activity|alkyl sulfatase activity|endosulfan hemisulfate sulfatase activity|endosulfan sulfate hydrolase activity|metal ion binding|,10,0.3,0.259,10,0,0,0.1,0.0914,0.0914,0.874,0,0,-1.8,1.2
ENSMUSG00000043635,ADAMTS3,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3",extracellular region|extracellular space|extracellular vesicular exosome|,proteolysis|integrin-mediated signaling pathway|vascular endothelial growth factor production|protein processing|protein processing|collagen biosynthetic process|positive regulation of vascular endothelial growth factor signaling pathway|,endopeptidase activity|peptidase activity|,10,-0.1,0.0734,10,0.1,0.211,0.1,0.0883,0.0883,0.875,0,0,-1.3,1.6
ENSMUSG00000000365,RNF17,ring finger protein 17,nucleus|cytoplasm|,multicellular organismal development|spermatogenesis|spermatid development|cell differentiation|,"nucleic acid binding|zinc ion binding|hydrolase activity, acting on ester bonds|protein homodimerization activity|metal ion binding|",10,0.3,1.48,10,-0.2,1.51,0.1,0.0873,0.0873,0.875,0,0,-1.4,1.5
ENSMUSG00000078974,SEC61G,"SEC61, gamma subunit",membrane|,biological_process|,molecular_function|,10,-0.2,0.24,10,0,0,-0.1,0.0846,-0.0846,0.876,0,0,-1.6,1.2
ENSMUSG00000021226,ACOT2,acyl-CoA thioesterase 2,mitochondrion|mitochondrion|mitochondrion|extracellular vesicular exosome|,very long-chain fatty acid metabolic process|response to hypoxia|long-chain fatty acid metabolic process|acyl-CoA metabolic process|acyl-CoA metabolic process|very long-chain fatty acid catabolic process|,receptor binding|palmitoyl-CoA hydrolase activity|hydrolase activity|thiolester hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|,10,-0.2,0.134,10,-0.1,0.0572,-0.1,0.0775,-0.0775,0.878,0,0,-1.9,1
ENSMUSG00000018474,CHD3,chromodomain helicase DNA binding protein 3,nucleus|nucleolus|cytoplasm|centrosome|NuRD complex|NuRD complex|intermediate filament cytoskeleton|,chromatin assembly or disassembly|spindle organization|centrosome organization|,protein binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,0.1,0.173,0.1,0.0757,0.0757,0.878,0,0,-1.4,1.6
ENSMUSG00000023235,CCL25,chemokine (C-C motif) ligand 25,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|leukocyte migration|cell chemotaxis|,cytokine activity|protein binding|chemokine activity|CCR10 chemokine receptor binding|chemokine receptor binding|,10,0,0,10,0.2,0.641,0.1,0.0715,0.0715,0.879,0,0,-1.3,1.6
ENSMUSG00000021071,TRIM9,tripartite motif-containing 9,intracellular|cytoplasm|cytoplasm|cytoskeleton|synaptic vesicle|cell junction|dendrite|dendrite|cytoplasmic vesicle|cell projection|synapse|,synaptic vesicle exocytosis|protein ubiquitination|negative regulation of SNARE complex assembly|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of calcium ion-dependent exocytosis|,"SNARE binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,1.28,9,0,0,-0.1,0.0706,-0.0706,0.88,0,0,-1.8,1.1
ENSMUSG00000020000,MOXD1,"monooxygenase, DBH-like 1",endoplasmic reticulum|membrane|integral component of membrane|,oxidation-reduction process|,"catalytic activity|monooxygenase activity|copper ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen|metal ion binding|",10,0,0,10,-0.3,0.788,0.1,0.0686,0.0686,0.88,0,0,-1.7,1.3
ENSMUSG00000067597,DGAT2L6,diacylglycerol O-acyltransferase 2-like 6,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|biological_process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.3,0.0958,10,1,0.714,0.9,0.0676,0.0676,0.88,0,0,-0.6,2
ENSMUSG00000001472,TCF25,transcription factor 25 (basic helix-loop-helix),nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,0,0,10,-0.2,0.415,-0.1,0.0675,-0.0675,0.88,0,0,-1.6,1.3
ENSMUSG00000006205,HTRA1,HtrA serine peptidase 1,extracellular region|cytoplasm|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,regulation of cell growth|proteolysis|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|positive regulation of epithelial cell proliferation|negative regulation of defense response to virus|,catalytic activity|serine-type endopeptidase activity|protein binding|insulin-like growth factor binding|peptidase activity|serine-type peptidase activity|hydrolase activity|growth factor binding|,10,0,0,10,-0.2,0.768,-0.1,0.067,-0.067,0.881,0,0,-1.9,1
ENSMUSG00000026630,BATF3,"basic leucine zipper transcription factor, ATF-like 3",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to virus|cell differentiation|myeloid dendritic cell differentiation|dendritic cell differentiation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.3,1.24,10,0,0,0.1,0.0649,0.0649,0.881,0,0,-0.8,2
ENSMUSG00000015653,STEAP2,six transmembrane epithelial antigen of prostate 2,endosome|early endosome|cytosol|plasma membrane|plasma membrane|membrane|integral component of membrane|trans-Golgi network transport vesicle|integral component of Golgi membrane|intracellular membrane-bounded organelle|,transport|ion transport|Golgi to plasma membrane transport|endocytosis|response to hormone|copper ion import|regulated secretory pathway|iron ion homeostasis|oxidation-reduction process|ferric iron import into cell|,transporter activity|cupric reductase activity|oxidoreductase activity|metal ion binding|ferric-chelate reductase (NADPH) activity|,10,-0.4,0.394,10,0,0,-0.1,0.0634,-0.0634,0.882,0,0,-1.8,1.2
ENSMUSG00000059486,KBTBD2,kelch repeat and BTB (POZ) domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,1.75,-0.2,0.0611,-0.0611,0.882,0,0,-1.6,1.1
ENSMUSG00000061517,SOX21,SRY (sex determining region Y)-box 21,nucleus|,"hair follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|hair cycle|skin development|negative regulation of neuron differentiation|stem cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,0.2,0.418,10,-0.1,0.463,0.1,0.0596,0.0596,0.882,0,0,-1.3,1.6
ENSMUSG00000018845,UNC45B,unc-45 homolog B (C. elegans),cytoplasm|cytosol|,multicellular organismal development|muscle organ development|cell differentiation|chaperone-mediated protein folding|,Hsp90 protein binding|,10,0,0,10,0.2,0.272,0.1,0.0583,0.0583,0.883,0,0,-1.2,1.7
ENSMUSG00000028822,TMEM50A,transmembrane protein 50A,cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|,None,None,10,-0.2,0.72,10,0.4,0.00988,-0.1,0.0568,-0.0568,0.883,0,0,-1.1,1.8
ENSMUSG00000033450,TAGAP,T cell activation Rho GTPase activating protein,intracellular|,signal transduction|,molecular_function|guanyl-nucleotide exchange factor activity|,10,0.2,0.112,10,0,0,0.1,0.0567,0.0567,0.883,0,0,-1.2,1.6
ENSMUSG00000039004,BMP6,bone morphogenetic protein 6,extracellular region|extracellular space|cytoplasm|membrane-bounded vesicle|,ossification|osteoblast differentiation|eye development|kidney development|positive regulation of endothelial cell proliferation|endochondral ossification|type B pancreatic cell development|immune response|multicellular organismal development|positive regulation of pathway-restricted SMAD protein phosphorylation|cell differentiation|positive regulation of bone mineralization|BMP signaling pathway|BMP signaling pathway|male genitalia development|positive regulation of chondrocyte differentiation|positive regulation of aldosterone biosynthetic process|growth|positive regulation of endothelial cell differentiation|positive regulation of neuron differentiation|positive regulation of osteoblast differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of epithelial cell proliferation|cartilage development|SMAD protein signal transduction|positive regulation of aldosterone secretion|,cytokine activity|protein binding|growth factor activity|protein heterodimerization activity|BMP receptor binding|,10,-0.1,0.0556,10,-0.1,0.00638,-0.1,0.0564,-0.0564,0.883,0,0,-1.4,1.5
ENSMUSG00000022200,GOLPH3,golgi phosphoprotein 3,Golgi membrane|mitochondrion|endosome|Golgi apparatus|trans-Golgi network|cytosol|plasma membrane|membrane|Golgi cisterna|,transport|Golgi organization|cell proliferation|glycoprotein biosynthetic process|protein secretion|gene expression|regulation of mitochondrion organization|protein transport|cell migration|lamellipodium assembly|positive regulation of TOR signaling|Golgi to plasma membrane protein transport|protein retention in Golgi apparatus|Golgi vesicle budding|positive regulation of protein secretion|leukocyte tethering or rolling|cell adhesion molecule production|,lipid binding|enzyme binding|phosphatidylinositol-4-phosphate binding|,6,0,0,6,0.1,0.0711,0.1,0.0561,0.0561,0.883,0,0,-1.5,1.8
ENSMUSG00000028834,TRIM63,tripartite motif-containing 63,intracellular|nucleus|cytoplasm|contractile fiber|,muscle contraction|regulation of gene expression|response to electrical stimulus involved in regulation of muscle adaptation|response to denervation involved in regulation of muscle adaptation|protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|cellular response to dexamethasone stimulus|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|titin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.113,10,0,0,0.1,0.0517,0.0517,0.885,0,0,-1,1.9
ENSMUSG00000023809,RPS6KA2,"ribosomal protein S6 kinase, polypeptide 2",nucleus|cytoplasm|cytoplasm|spindle|nuclear membrane|,oocyte maturation|brain renin-angiotensin system|protein phosphorylation|protein phosphorylation|heart development|negative regulation of cell proliferation|positive regulation of gene expression|cardiac muscle cell apoptotic process|phosphorylation|peptidyl-serine phosphorylation|intracellular signal transduction|positive regulation of apoptotic process|negative regulation of cell cycle|negative regulation of meiosis|heart contraction|regulation of protein processing|regulation of protein processing|cellular response to carbohydrate stimulus|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ribosomal protein S6 kinase activity|protein serine/threonine/tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.1,0.132,0.1,0.0514,0.0514,0.885,0,0,-1.3,2
ENSMUSG00000001023,S100A5,S100 calcium binding protein A5,nucleus|neuronal cell body|,biological_process|,copper ion binding|calcium ion binding|zinc ion binding|protein homodimerization activity|metal ion binding|,10,-0.2,0.724,10,0.2,0.735,-0.1,0.0486,-0.0486,0.886,0,0,-1.5,1.3
ENSMUSG00000021972,HMBOX1,homeobox containing 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",DNA binding|,10,-0.2,0.654,10,0.1,0.0811,0.1,0.0464,0.0464,0.886,0,0,-1.5,1.4
ENSMUSG00000040007,BAHD1,bromo adjacent homology domain containing 1,nucleus|chromatin silencing complex|chromosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|heterochromatin assembly|negative regulation of transcription, DNA-templated|",chromatin binding|,10,0,0,10,0.1,0.166,0.1,0.0464,0.0464,0.886,0,0,-1.2,1.7
ENSMUSG00000027253,LRP4,low density lipoprotein receptor-related protein 4,plasma membrane|cell surface|postsynaptic density|membrane|integral component of membrane|flotillin complex|dendrite|neuromuscular junction|neuromuscular junction|neuronal cell body|synaptic membrane|,kidney development|kidney development|regulation of protein phosphorylation|hair follicle development|endocytosis|multicellular organismal development|protein localization|dorsal/ventral pattern formation|proximal/distal pattern formation|Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|negative regulation of ossification|embryonic limb morphogenesis|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|receptor clustering|dendrite morphogenesis|anatomical structure development|negative regulation of axonogenesis|synapse organization|synaptic growth at neuromuscular junction|synaptic growth at neuromuscular junction|protein heterotetramerization|limb development|skeletal muscle acetylcholine-gated channel clustering|negative regulation of canonical Wnt signaling pathway|postsynaptic membrane assembly|presynaptic membrane assembly|positive regulation of presynaptic membrane organization|,calcium ion binding|protein binding|receptor tyrosine kinase binding|apolipoprotein binding|protein homodimerization activity|scaffold protein binding|,10,-0.1,0.0168,10,-0.1,0.0315,-0.1,0.0439,-0.0439,0.887,0,0,-1.6,1.4
ENSMUSG00000027288,ZFP106,zinc finger protein 106,nucleus|cytoplasm|cytosol|membrane|,insulin receptor signaling pathway|,opioid peptide activity|SH3 domain binding|poly(A) RNA binding|metal ion binding|,10,0.4,1.47,10,-0.1,0.225,-0.1,0.0436,-0.0436,0.887,0,0,-0.7,2
ENSMUSG00000041717,GOLT1A,golgi transport 1 homolog A (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,2,0.1,0.123,2,0,0,0.1,0.0425,0.0425,0.887,0,0,-1.7,2
ENSMUSG00000043556,FBXL7,F-box and leucine-rich repeat protein 7,cytoplasm|centrosome|cytoskeleton|SCF ubiquitin ligase complex|,G2/M transition of mitotic cell cycle|cell cycle|mitotic nuclear division|cell proliferation|protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cell division|,protein binding|,10,0,0,10,0.1,0.409,0.1,0.0392,0.0392,0.888,0,0,-1.3,1.7
ENSMUSG00000037463,FBXO27,F-box protein 27,SCF ubiquitin ligase complex|,biological_process|,glycoprotein binding|,10,-0.4,1,10,0,0,-0.1,0.0338,-0.0338,0.889,0,0,-1.9,0.8
ENSMUSG00000006403,ADAMTS4,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|,proteolysis|proteolysis|defense response to bacterium|,protease binding|metalloendopeptidase activity|protein binding|peptidase activity|metallopeptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.1,0.211,10,0.1,0.011,-0.1,0.0336,-0.0336,0.889,0,0,-1.5,1.4
ENSMUSG00000057729,PRTN3,proteinase 3,extracellular space|cytosol|plasma membrane|extracellular matrix|extracellular vesicular exosome|,proteolysis|collagen catabolic process|negative regulation of phagocytosis|mature dendritic cell differentiation|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|enzyme binding|,10,0,0,10,-0.4,1.71,-0.1,0.0312,-0.0312,0.89,0,0,-1.5,1.4
ENSMUSG00000004633,CHN2,chimerin 2,intracellular|membrane|synapse|,signal transduction|intracellular signal transduction|positive regulation of GTPase activity|,GTPase activator activity|metal ion binding|,10,-0.1,0.0926,10,0.1,0.379,0.1,0.0299,0.0299,0.89,0,0,-1.1,1.8
ENSMUSG00000020536,LLGL1,lethal giant larvae homolog 1 (Drosophila),Golgi cis cisterna|cytoplasm|cytoplasm|endosome|Golgi apparatus|cytoskeleton|membrane|axon|cortical actin cytoskeleton|early endosome membrane|trans-Golgi network membrane|myelin sheath abaxonal region|cell projection|,protein complex assembly|exocytosis|Golgi to plasma membrane transport|axonogenesis|brain development|cortical actin cytoskeleton organization|positive regulation of Rab GTPase activity|maintenance of apical/basal cell polarity|,Rab GTPase activator activity|Rab GTPase binding|protein kinase binding|,10,0.1,0.0954,10,-0.2,0.236,-0.1,0.0293,-0.0293,0.89,0,0,-1.7,1.1
ENSMUSG00000025195,DNMBP,dynamin binding protein,cytoplasm|Golgi apparatus|cytoskeleton|cell junction|synapse|,regulation of Rho protein signal transduction|intracellular signal transduction|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|,10,-0.4,1.88,10,0.2,0.267,-0.3,0.0253,-0.0253,0.891,0,0,-1.7,1.2
ENSMUSG00000021999,CPB2,carboxypeptidase B2 (plasma),extracellular region|extracellular space|,positive regulation of extracellular matrix constituent secretion|proteolysis|proteolysis|blood coagulation|hemostasis|response to heat|negative regulation of plasminogen activation|fibrinolysis|negative regulation of fibrinolysis|negative regulation of hepatocyte proliferation|,carboxypeptidase activity|carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,9,-0.1,0.198,9,0.9,1.69,0.1,0.0234,0.0234,0.892,0,0,-0.7,2
ENSMUSG00000030816,RNF40,ring finger protein 40,ubiquitin ligase complex|nucleus|membrane|HULC complex|neuron projection|protein complex|,ubiquitin-dependent protein catabolic process|histone monoubiquitination|chromatin modification|histone H2B ubiquitination|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|syntaxin-1 binding|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|protein complex binding|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.902,10,-0.2,0.651,0.1,0.0227,0.0227,0.892,0,0,-1.4,1.5
ENSMUSG00000038876,RNF146,ring finger protein 146,nucleus|cytoplasm|cytosol|,Wnt signaling pathway|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein autoubiquitination|protein K48-linked ubiquitination|positive regulation of canonical Wnt signaling pathway|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|poly-ADP-D-ribose binding|",10,0,0,10,-0.8,1.24,-0.1,0.0186,-0.0186,0.893,0,0,-2,1
ENSMUSG00000048206,DNAJB8,"DnaJ (Hsp40) homolog, subfamily B, member 8",nucleus|cytosol|,chaperone-mediated protein folding|negative regulation of inclusion body assembly|,protein binding involved in protein folding|unfolded protein binding|chaperone binding|,10,0.3,0.545,10,0,0,0.3,0.0184,0.0184,0.893,0,0,-0.8,1.9
ENSMUSG00000035069,OMA1,"OMA1 homolog, zinc metallopeptidase (S. cerevisiae)",mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial membrane|,diet induced thermogenesis|glucose metabolic process|proteolysis|misfolded or incompletely synthesized protein catabolic process|lipid metabolic process|response to stress|mitochondrion organization|negative regulation of mitochondrial fusion|mitochondrial protein processing|cristae formation|energy homeostasis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,0.1,0.305,10,-0.1,0.09,0.1,0.0167,0.0167,0.894,0,0,-1,1.8
ENSMUSG00000021099,SIX6,sine oculis-related homeobox 6,nucleus|,transcription from RNA polymerase II promoter|multicellular organismal development|positive regulation of transcription from RNA polymerase II promoter|,RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|protein binding|,10,0,0,10,-0.2,0.836,-0.1,0.00991,-0.00991,0.895,0,0,-1.7,1.2
ENSMUSG00000023926,RHAG,Rhesus blood group-associated A glycoprotein,plasma membrane|membrane|integral component of membrane|,transport|cellular ion homeostasis|carbon dioxide transport|organic cation transport|ammonium transport|ammonium transport|erythrocyte development|multicellular organismal iron ion homeostasis|ammonium transmembrane transport|,ammonium transmembrane transporter activity|ankyrin binding|,10,-0.2,0.59,10,0.1,0.154,-0.1,0.00519,-0.00519,0.897,0,0,-1.4,1.5
ENSMUSG00000026854,USP20,ubiquitin specific peptidase 20,cytoplasm|centrosome|cytoskeleton|,proteolysis|ubiquitin-dependent protein catabolic process|endocytosis|regulation of G-protein coupled receptor protein signaling pathway|protein deubiquitination|protein K63-linked deubiquitination|protein K48-linked deubiquitination|,G-protein coupled receptor binding|cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|metal ion binding|,10,0,0,10,-0.2,0.784,-0.1,0.000153,-0.000153,0.898,0,0,-1.6,1.3
ENSMUSG00000063531,SEMA3E,"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E",extracellular region|membrane|,angiogenesis|patterning of blood vessels|negative regulation of cell-matrix adhesion|sprouting angiogenesis|multicellular organismal development|nervous system development|regulation of cell shape|negative regulation of angiogenesis|cell differentiation|synapse organization|semaphorin-plexin signaling pathway|regulation of actin cytoskeleton reorganization|,receptor activity|protein binding|,10,-0.1,0.0117,10,0.2,0.595,0.1,3.37E-05,0.0000337,0.898,0,0,-1.3,1.6
ENSMUSG00000035357,PDZRN3,PDZ domain containing RING finger 3,neuromuscular junction|,neuromuscular junction development|protein ubiquitination|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.533,10,0,0,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000021710,NLN,neurolysin (metallopeptidase M3 family),cytoplasm|mitochondrion|plasma membrane|,proteolysis|biological_process|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|peptide binding|metal ion binding|,10,0.2,0.358,10,0,0,0,0,0,0.898,0,0,-1.1,1.8
ENSMUSG00000020455,TRIM11,tripartite motif-containing 11,intracellular|nucleus|cytoplasm|cytoplasm|,"protein ubiquitination|negative regulation of viral transcription|negative regulation of viral transcription|innate immune response|innate immune response|negative regulation of transcription, DNA-templated|negative regulation of viral entry into host cell|negative regulation of viral entry into host cell|positive regulation of viral entry into host cell|positive regulation of viral entry into host cell|negative regulation of neurogenesis|defense response to virus|negative regulation of viral release from host cell|negative regulation of viral release from host cell|","ubiquitin-protein transferase activity|protein binding|transcription factor binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein domain specific binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.3,1.8
ENSMUSG00000038402,FOXF2,forkhead box F2,nucleus|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|extracellular matrix organization|extracellular matrix organization|establishment of planar polarity of embryonic epithelium|establishment of planar polarity of embryonic epithelium|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|embryonic digestive tract development|embryonic camera-type eye morphogenesis|genitalia development|palate development|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription factor binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1,2
ENSMUSG00000003184,IRF3,interferon regulatory factor 3,nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|response to bacterium|lipopolysaccharide-mediated signaling pathway|response to lipopolysaccharide|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|positive regulation of interferon-beta production|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to exogenous dsRNA|innate immune response|type I interferon biosynthetic process|negative regulation of interferon-beta biosynthetic process|negative regulation of defense response to virus by host|positive regulation of cytokine secretion|defense response to virus|positive regulation of type I interferon-mediated signaling pathway|programmed necrotic cell death|",regulatory region DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|identical protein binding|protein homodimerization activity|protein homodimerization activity|transcription regulatory region DNA binding|,10,0,0,10,0.1,0.44,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000036882,ARHGAP33,Rho GTPase activating protein 33,intracellular|cytoplasm|plasma membrane|membrane|,transport|signal transduction|protein transport|positive regulation of Rac GTPase activity|,GTPase activator activity|Rho GTPase activator activity|protein binding|Rac GTPase activator activity|phosphatidylinositol binding|,10,-0.6,0.431,10,0.1,0.0984,0,0,0,0.898,0,0,-1.9,1.2
ENSMUSG00000031145,PRICKLE3,prickle homolog 3 (Drosophila),cellular_component|,biological_process|,zinc ion binding|metal ion binding|,10,0,0,10,-0.1,0.206,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000026771,SPOPL,speckle-type POZ protein-like,nucleus|Cul3-RING ubiquitin ligase complex|,negative regulation of protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|,molecular_function|,10,-0.5,0.887,10,0,0,0,0,0,0.898,0,0,-2,0.9
ENSMUSG00000053399,ADAMTS18,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18",cellular_component|extracellular region|proteinaceous extracellular matrix|extracellular matrix|,eye development|proteolysis|negative regulation of platelet aggregation|negative regulation of platelet aggregation|,molecular_function|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.1,0.0312,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000062478,CTRC,chymotrypsin C (caldecrin),cellular_component|,proteolysis|cellular calcium ion homeostasis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.4,0.142,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000021263,DEGS2,"degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase",endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|sphinganine metabolic process|sphinganine metabolic process|sphingolipid biosynthetic process|ceramide biosynthetic process|oxidation-reduction process|,"sphingosine hydroxylase activity|N-ethylmaleimide reductase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|fluorene oxygenase activity|mono-butyltin dioxygenase activity|tri-n-butyltin dioxygenase activity|di-n-butyltin dioxygenase activity|methylsilanetriol hydroxylase activity|methyl tertiary butyl ether 3-monooxygenase activity|4-nitrocatechol 4-monooxygenase activity|4-chlorophenoxyacetate monooxygenase activity|tert-butanol 2-monooxygenase activity|alpha-pinene monooxygenase activity|dimethylsilanediol hydroxylase activity|ammonia monooxygenase activity|hydroxymethylsilanetriol oxidase activity|2-hydroxyisobutyrate 3-monooxygenase activity|alpha-pinene dehydrogenase activity|bisphenol A hydroxylase B activity|2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity|9-fluorenone-3,4-dioxygenase activity|anthracene 9,10-dioxygenase activity|2-(methylthio)benzothiazole monooxygenase activity|2-hydroxybenzothiazole monooxygenase activity|benzothiazole monooxygenase activity|2,6-dihydroxybenzothiazole monooxygenase activity|pinacolone 5-monooxygenase activity|thioacetamide S-oxygenase activity|thioacetamide S-oxide S-oxygenase activity|endosulfan monooxygenase I activity|N-nitrodimethylamine hydroxylase activity|4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity|endosulfan ether monooxygenase activity|pyrene 4,5-monooxygenase activity|pyrene 1,2-monooxygenase activity|1-hydroxypyrene 6,7-monooxygenase activity|1-hydroxypyrene 7,8-monooxygenase activity|phenylboronic acid monooxygenase activity|sphingolipid delta-4 desaturase activity|reduced coenzyme F420 dehydrogenase activity|spheroidene monooxygenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|",10,0.1,0.186,10,0,0,0,0,0,0.898,0,0,-1.6,1.3
ENSMUSG00000000673,HAAO,"3-hydroxyanthranilate 3,4-dioxygenase",cytoplasm|cytosol|mitochondrial membrane|extracellular vesicular exosome|,response to zinc ion|pyridine nucleotide biosynthetic process|response to cadmium ion|quinolinate metabolic process|oxidation-reduction process|neuron cellular homeostasis|,"3-hydroxyanthranilate 3,4-dioxygenase activity|3-hydroxyanthranilate 3,4-dioxygenase activity|iron ion binding|ferrous iron binding|oxidoreductase activity|oxygen binding|metal ion binding|dioxygenase activity|",10,0.8,2.4,10,-0.1,0.0171,0,0,0,0.898,0,0,-0.6,2
ENSMUSG00000024350,DNAJC18,"DnaJ (Hsp40) homolog, subfamily C, member 18",cellular_component|membrane|integral component of membrane|,biological_process|,None,10,0.1,0.0424,10,0,0,0,0,0,0.898,0,0,-1,2
ENSMUSG00000023973,CNPY3,canopy 3 homolog (zebrafish),endoplasmic reticulum|,immune system process|innate immune response|,receptor binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000040554,AIPL1,aryl hydrocarbon receptor-interacting protein-like 1,photoreceptor inner segment|nucleus|cytoplasm|,"retina homeostasis|protein folding|phototransduction, visible light|protein farnesylation|regulation of cGMP metabolic process|negative regulation of apoptotic process|",farnesylated protein binding|,10,0,0,10,-0.1,0.11,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000036634,MAG,myelin-associated glycoprotein,membrane|integral component of membrane|paranode region of axon|myelin sheath|Schmidt-Lanterman incisure|,cell adhesion|,protein binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.1,2
ENSMUSG00000096727,PSMB9,"proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)",proteasome complex|nucleus|cytoplasm|proteasome core complex|extracellular vesicular exosome|spermatoproteasome complex|,immune system process|proteolysis|antigen processing and presentation|antigen processing and presentation|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,0.2,0.00629,10,0,0,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000034413,NEURL1B,neuralized homolog 1b (Drosophila),cellular_component|cytoplasm|,Notch signaling pathway|biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.7,1.4
ENSMUSG00000036534,SLC38A7,"solute carrier family 38, member 7",membrane|integral component of membrane|axon|neuronal cell body|,transport|ion transport|sodium ion transport|drug transmembrane transport|amino acid transport|asparagine transport|glutamine transport|branched-chain amino acid transport|L-alanine transport|aspartate transport|L-glutamate transport|histidine transport|methionine transport|L-serine transport|L-alpha-amino acid transmembrane transport|,L-histidine transmembrane transporter activity|L-glutamate transmembrane transporter activity|L-amino acid transmembrane transporter activity|L-alanine transmembrane transporter activity|L-asparagine transmembrane transporter activity|L-aspartate transmembrane transporter activity|L-glutamine transmembrane transporter activity|L-leucine transmembrane transporter activity|L-methionine transmembrane transporter activity|L-serine transmembrane transporter activity|,10,0.1,0.129,10,-0.3,0.895,0,0,0,0.898,0,0,-1.8,1.4
ENSMUSG00000029428,STX2,syntaxin 2,cell-cell junction|cell surface|membrane|integral component of membrane|basolateral plasma membrane|transport vesicle|midbody|cytoplasmic vesicle|membrane raft|extracellular vesicular exosome|,intracellular protein transport|acrosome reaction|embryo implantation|regulation of gene expression|vesicle-mediated transport|microvillus assembly|cell differentiation|regulation of blood coagulation|epithelial cell differentiation|digestive tract morphogenesis|,SNARE binding|SNAP receptor activity|protein binding|calcium-dependent protein binding|,10,0,0,10,-0.1,0.145,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000020646,MBOAT2,membrane bound O-acyltransferase domain containing 2,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|biological_process|phospholipid biosynthetic process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|1-acylglycerophosphocholine O-acyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-2,1
ENSMUSG00000041679,LRRC29,leucine rich repeat containing 29,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.3,1.8
ENSMUSG00000046861,HECTD3,HECT domain containing 3,nucleus|cytoplasm|perinuclear region of cytoplasm|,protein ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|syntaxin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.224,10,0.1,0.408,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000063447,UBE2D2B,ubiquitin-conjugating enzyme E2D 2B,cellular_component|,protein K29-linked ubiquitination|protein K27-linked ubiquitination|protein K63-linked ubiquitination|protein K48-linked ubiquitination|protein K11-linked ubiquitination|protein K6-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0.2,0.369,10,0,0,0,0,0,0.898,0,0,-1.3,1.6
ENSMUSG00000027875,HMGCS2,3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2,mitochondrion|mitochondrial inner membrane|mitochondrial matrix|,lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|metabolic process|steroid metabolic process|cholesterol metabolic process|isoprenoid biosynthetic process|sterol biosynthetic process|,catalytic activity|hydroxymethylglutaryl-CoA synthase activity|transferase activity|,10,0,0,10,-0.2,0.764,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000058317,UBE2E2,ubiquitin-conjugating enzyme E2E 2,None,ISG15-protein conjugation|protein K63-linked ubiquitination|protein K48-linked ubiquitination|protein K11-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|ISG15 ligase activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.1,1.8
ENSMUSG00000045903,NPAS4,neuronal PAS domain protein 4,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|signal transducer activity|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|,10,0.1,0.113,10,-0.7,1.27,0,0,0,0.898,0,0,-2,0.9
ENSMUSG00000034110,KCTD7,potassium channel tetramerisation domain containing 7,cellular_component|cytoplasm|plasma membrane|membrane|,biological_process|protein homooligomerization|,molecular_function|,10,0.1,0.065,10,1.1,1.81,0,0,0,0.898,0,0,-0.4,2
ENSMUSG00000030509,ASB7,ankyrin repeat and SOCS box-containing 7,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0.7,1.16,10,0,0,0,0,0,0.898,0,0,-0.7,2
ENSMUSG00000021893,CAPN7,calpain 7,intracellular|nucleus|cytoplasm|cytoplasm|extracellular vesicular exosome|,proteolysis|positive regulation of epithelial cell migration|self proteolysis|,endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|MIT domain binding|,10,0.1,0.069,10,-0.1,0.175,0,0,0,0.898,0,0,-1.5,1.4
ENSMUSG00000027220,SYT13,synaptotagmin XIII,integral component of plasma membrane|membrane|integral component of membrane|transport vesicle|cytoplasmic vesicle|,vesicle-mediated transport|,molecular_function|,10,0,0,10,-0.6,1.69,0,0,0,0.898,0,0,-2,0.6
ENSMUSG00000019818,CD164,CD164 antigen,lysosome|endosome|plasma membrane|membrane|integral component of membrane|,cell adhesion|heterophilic cell-cell adhesion|muscle organ development|,protein binding|,10,0.2,0.999,10,-0.1,0.302,0,0,0,0.898,0,0,-1.2,1.7
ENSMUSG00000037295,LDLRAP1,low density lipoprotein receptor adaptor protein 1,cytoplasm|early endosome|early endosome|cytosol|neurofilament|cytoplasmic side of plasma membrane|basal plasma membrane|AP-1 adaptor complex|AP-2 adaptor complex|axon|recycling endosome|,lipid metabolic process|endocytosis|receptor-mediated endocytosis|steroid metabolic process|cholesterol metabolic process|positive regulation of signal transduction|receptor internalization|cholesterol homeostasis|cholesterol homeostasis|amyloid precursor protein metabolic process|regulation of protein binding|positive regulation of receptor-mediated endocytosis|regulation of establishment of protein localization to plasma membrane|receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|,"beta-amyloid binding|beta-amyloid binding|phosphotyrosine binding|receptor binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|receptor signaling complex scaffold activity|clathrin binding|clathrin binding|signaling adaptor activity|AP-2 adaptor complex binding|clathrin adaptor activity|low-density lipoprotein particle receptor binding|",9,0,0,10,0.2,0.785,0,0,0,0.898,0,0,-1.1,1.8
ENSMUSG00000028096,GPR89,G protein-coupled receptor 89,Golgi apparatus|membrane|integral component of membrane|Golgi-associated vesicle membrane|Golgi cisterna membrane|,transport|ion transport|anion transport|signal transduction|protein transport|ion transmembrane transport|regulation of ion transmembrane transport|skin development|regulation of anion transport|,signal transducer activity|voltage-gated ion channel activity|voltage-gated anion channel activity|,10,0,0,10,1,1.11,0,0,0,0.898,0,0,-1.2,2
ENSMUSG00000026509,CAPN2,calpain 2,chromatin|intracellular|nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|membrane|dendrite|pseudopodium|membrane raft|membrane raft|extracellular vesicular exosome|perinuclear endoplasmic reticulum|,blastocyst development|proteolysis|proteolysis|proteolysis|myoblast fusion|protein autoprocessing|cellular response to amino acid stimulus|cellular response to amino acid stimulus|,calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|cytoskeletal protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|protein heterodimerization activity|,10,0,0,10,-0.9,1.77,0,0,0,0.898,0,0,-2,0.7
ENSMUSG00000041870,ANKRD13A,ankyrin repeat domain 13a,endosome|plasma membrane|membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.8,1.2
ENSMUSG00000040170,FMO2,flavin containing monooxygenase 2,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,organic acid metabolic process|NADP metabolic process|xenobiotic metabolic process|toxin metabolic process|drug metabolic process|oxidation-reduction process|NADPH oxidation|oxygen metabolic process|,"monooxygenase activity|N,N-dimethylaniline monooxygenase activity|oxidoreductase activity|flavin adenine dinucleotide binding|NADP binding|",10,0.3,1.04,10,0,0,0,0,0,0.898,0,0,-1.2,1.7
ENSMUSG00000026696,VAMP4,vesicle-associated membrane protein 4,intracellular|cell|Golgi apparatus|trans-Golgi network|cell surface|membrane|integral component of membrane|SNARE complex|,vesicle-mediated transport|SNARE complex assembly|regulation of Golgi to plasma membrane protein transport|Golgi to plasma membrane protein transport|,None,10,0,0,10,0.1,0.201,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000027068,DHRS9,dehydrogenase/reductase (SDR family) member 9,cytoplasm|endoplasmic reticulum|membrane|integral component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,metabolic process|androgen metabolic process|progesterone metabolic process|9-cis-retinoic acid biosynthetic process|oxidation-reduction process|,"alcohol dehydrogenase (NAD) activity|retinol dehydrogenase activity|oxidoreductase activity|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|versicolorin reductase activity|ketoreductase activity|testosterone dehydrogenase (NAD+) activity|",10,0.1,0.0332,10,0,0,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000021313,RYR2,"ryanodine receptor 2, cardiac",intracellular|cell|nuclear envelope|cytoplasm|endoplasmic reticulum|smooth endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|sarcomere|Z disc|Z disc|Z disc|extrinsic component of cytoplasmic side of plasma membrane|A band|sarcoplasmic reticulum membrane|sarcoplasmic reticulum membrane|calcium channel complex|calcium channel complex|sarcolemma|neuron projection|protein complex|extracellular vesicular exosome|,response to hypoxia|regulation of heart rate|regulation of heart rate|embryonic heart tube morphogenesis|left ventricular cardiac muscle tissue morphogenesis|cardiac muscle hypertrophy|detection of calcium ion|transport|ion transport|calcium ion transport|calcium ion transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|multicellular organismal development|positive regulation of heart rate|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|calcium-mediated signaling|BMP signaling pathway|response to caffeine|response to caffeine|response to magnesium ion|ion transmembrane transport|calcium-mediated signaling using intracellular calcium source|release of sequestered calcium ion into cytosol|positive regulation of sequestering of calcium ion|cytosolic calcium ion homeostasis|negative regulation of cytosolic calcium ion concentration|response to calcium ion|response to redox state|transmembrane transport|regulation of cardiac muscle contraction|cardiac muscle contraction|canonical Wnt signaling pathway|cytosolic calcium ion transport|calcium ion transport into cytosol|sarcoplasmic reticulum calcium ion transport|calcium ion transmembrane transport|calcium ion transmembrane transport|calcium ion transmembrane transport|cellular response to caffeine|cellular response to caffeine|manganese ion transmembrane transport|establishment of protein localization to endoplasmic reticulum|ventricular cardiac muscle cell action potential|Purkinje myocyte to ventricular cardiac muscle cell signaling|positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction|type B pancreatic cell apoptotic process|type B pancreatic cell apoptotic process|positive regulation of calcium-transporting ATPase activity|,ion channel activity|intracellular ligand-gated calcium channel activity|ryanodine-sensitive calcium-release channel activity|ryanodine-sensitive calcium-release channel activity|calcium channel activity|binding|calcium ion binding|protein binding|calmodulin binding|calmodulin binding|calcium-release channel activity|enzyme binding|enzyme binding|protein kinase binding|protein kinase A catalytic subunit binding|protein kinase A regulatory subunit binding|identical protein binding|protein self-association|suramin binding|calcium-induced calcium release activity|scaffold protein binding|,10,0.2,0.484,10,0,0,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000029524,SIRT4,sirtuin 4,mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial matrix|,protein ADP-ribosylation|glutamine metabolic process|cellular response to DNA damage stimulus|peptidyl-lysine deacetylation|negative regulation of fatty acid oxidation|negative regulation of insulin secretion|negative regulation of insulin secretion|negative regulation of insulin secretion|positive regulation of lipid biosynthetic process|tricarboxylic acid metabolic process|,"imidazoleglycerol-phosphate synthase activity|NAD+ ADP-ribosyltransferase activity|NAD+ ADP-ribosyltransferase activity|NAD+ ADP-ribosyltransferase activity|histone deacetylase activity|protein binding|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|transferase activity|hydrolase activity|NAD(P)-cysteine ADP-ribosyltransferase activity|NAD(P)-asparagine ADP-ribosyltransferase activity|NAD(P)-serine ADP-ribosyltransferase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|NAD-dependent protein deacetylase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|7-cyano-7-deazaguanine tRNA-ribosyltransferase activity|N-acetylcitrulline deacetylase activity|purine deoxyribosyltransferase activity|metal ion binding|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|NAD+ binding|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.7,1.4
ENSMUSG00000020634,UBXN2A,UBX domain protein 2A,endoplasmic reticulum|cis-Golgi network|cytosol|,regulation of gene expression|regulation of protein ubiquitination|regulation of protein catabolic process|,acetylcholine receptor binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000039234,SEC24D,"Sec24 related gene family, member D (S. cerevisiae)",cellular_component|,in utero embryonic development|transport|protein transport|,molecular_function|,10,-0.1,0.153,10,0.1,0.0596,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000031066,USP11,ubiquitin specific peptidase 11,nucleus|cytoplasm|,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000031543,ANK1,"ankyrin 1, erythroid",nucleus|cytoplasm|cytoskeleton|plasma membrane|spectrin-associated cytoskeleton|spectrin-associated cytoskeleton|membrane|sarcoplasmic reticulum|Z disc|axolemma|cortical cytoskeleton|M band|A band|sarcolemma|neuron projection|postsynaptic membrane|,porphyrin-containing compound biosynthetic process|ER to Golgi vesicle-mediated transport|signal transduction|positive regulation of organelle organization|monovalent inorganic cation transport|erythrocyte development|protein targeting to plasma membrane|,cytoskeletal adaptor activity|enzyme binding|spectrin binding|ATPase binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.6
ENSMUSG00000031519,ASB5,ankyrin repeat and SOCs box-containing 5,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,1.2,0.904,0,0,0,0.898,0,0,-0.9,2
ENSMUSG00000051527,USP29,ubiquitin specific peptidase 29,None,proteolysis|ubiquitin-dependent protein catabolic process|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0,0,10,-0.1,0.214,0,0,0,0.898,0,0,-2,0.8
ENSMUSG00000032376,USP3,ubiquitin specific peptidase 3,nuclear chromatin|nucleus|,negative regulation of transcription from RNA polymerase II promoter|mitotic cell cycle|DNA repair|proteolysis|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|cell cycle|chromatin modification|histone deubiquitination|regulation of protein stability|,core promoter sequence-specific DNA binding|chromatin binding|ubiquitin thiolesterase activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|histone binding|metal ion binding|,10,0,0,9,0.2,0.405,0,0,0,0.898,0,0,-1,2
ENSMUSG00000048285,FRMD6,FERM domain containing 6,cytoplasm|cytoskeleton|plasma membrane|membrane|apical junction complex|,apical constriction|regulation of actin filament-based process|cellular protein localization|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000031993,SNX19,sorting nexin 19,cellular_component|,biological_process|,molecular_function|,9,0.8,0.869,9,0,0,0,0,0,0.898,0,0,-1,2
ENSMUSG00000028088,FMO5,flavin containing monooxygenase 5,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|,"monooxygenase activity|N,N-dimethylaniline monooxygenase activity|oxidoreductase activity|flavin adenine dinucleotide binding|NADP binding|",10,0.2,0.558,10,0,0,0,0,0,0.898,0,0,-1.4,1.5
ENSMUSG00000035247,HECTD1,HECT domain containing 1,nucleus|cytoplasm|,neural tube closure|protein ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.0164,10,0.1,0.149,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000051048,P4HA3,"procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III",cellular_component|endoplasmic reticulum|,peptidyl-proline hydroxylation|oxidation-reduction process|,"procollagen-proline 4-dioxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|L-ascorbic acid binding|metal ion binding|dioxygenase activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000013878,RNF170,ring finger protein 170,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1,0.546,10,-0.3,0.579,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000028713,CYP4B1,"cytochrome P450, family 4, subfamily b, polypeptide 1",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,cellular aromatic compound metabolic process|biphenyl metabolic process|fluorene metabolic process|exogenous drug catabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|drug binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|fluorene oxygenase activity|heme binding|metal ion binding|aromatase activity|",10,0,0,10,-0.1,0.0134,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000030031,KBTBD8,kelch repeat and BTB (POZ) domain containing 8,cellular_component|cytoplasm|Golgi apparatus|cytoskeleton|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000051618,UBQLN3,ubiquilin 3,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.18,0,0,0,0.898,0,0,-1.1,2
ENSMUSG00000062627,MYSM1,"myb-like, SWIRM and MPN domains 1",nucleus|,"chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|chromatin modification|monoubiquitinated histone H2A deubiquitination|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|chromatin binding|transcription coactivator activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|metallopeptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|protein complex binding|histone binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000039016,TIMM8B,translocase of inner mitochondrial membrane 8B,extracellular space|mitochondrion|mitochondrial inner membrane|membrane|,transport|protein transport|,metal ion binding|,10,0.1,0.0661,10,0,0,0,0,0,0.898,0,0,-1.2,1.7
ENSMUSG00000060890,ARR3,"arrestin 3, retinal",photoreceptor outer segment|photoreceptor inner segment|synapse|,regulation of protein phosphorylation|regulation of protein phosphorylation|endocytosis|signal transduction|visual perception|response to stimulus|,opsin binding|protein domain specific binding|phosphoprotein binding|,10,-0.5,0.159,10,0.1,0.0822,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000071657,BSCL2,Berardinelli-Seip congenital lipodystrophy 2 homolog (seipin),endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,lipid metabolic process|lipid catabolic process|lipid storage|lipid particle organization|fat cell differentiation|negative regulation of lipid catabolic process|,None,10,-0.3,0.261,10,0.4,0.0607,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000068877,SELENBP2,selenium binding protein 2,extracellular space|nucleus|cytoplasm|membrane|extracellular vesicular exosome|,transport|protein transport|,selenium binding|,10,-0.1,0.21,10,0,0,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000055725,PAQR3,progestin and adipoQ receptor family member III,Golgi apparatus|membrane|integral component of membrane|,negative regulation of protein phosphorylation|negative regulation of protein phosphorylation|negative regulation of neuron projection development|negative regulation of peptidyl-serine phosphorylation|protein localization to Golgi apparatus|negative regulation of MAP kinase activity|negative regulation of MAP kinase activity|,receptor activity|,10,-0.1,0.517,10,0.1,0.381,0,0,0,0.898,0,0,-1.3,1.6
ENSMUSG00000041681,IAPP,islet amyloid polypeptide,extracellular region|extracellular space|neuronal cell body|,sensory perception of pain|eating behavior|negative regulation of cell differentiation|negative regulation of cell differentiation|negative regulation of bone resorption|,hormone activity|identical protein binding|,10,0.1,0.0295,10,-1,2.05,0,0,0,0.898,0,0,-2,0.7
ENSMUSG00000031988,VPS26B,vacuolar protein sorting 26 homolog B (yeast),cytoplasm|membrane|intracellular membrane-bounded organelle|,transport|protein transport|,None,10,0,0,10,0.1,0.208,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000038206,FBXO8,F-box protein 8,ubiquitin ligase complex|nucleus|cell junction|,ubiquitin-dependent protein catabolic process|actin cytoskeleton organization|regulation of ARF protein signal transduction|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|,10,0.1,0.112,10,-0.1,0.115,0,0,0,0.898,0,0,-1.4,1.5
ENSMUSG00000030761,MYO7A,myosin VIIA,intracellular|cell|cytoplasm|cytoplasm|cytoplasm|lysosomal membrane|cytosol|cytoskeleton|microvillus|apical plasma membrane|myosin complex|myosin VII complex|photoreceptor connecting cilium|stereocilium|melanosome|synapse|,phagolysosome assembly|ATP catabolic process|transport|intracellular protein transport|phagocytosis|lysosome organization|sensory perception|visual perception|visual perception|sensory perception of sound|sensory perception of sound|metabolic process|cell projection organization|actin filament-based movement|inner ear morphogenesis|mechanoreceptor differentiation|auditory receptor cell differentiation|post-embryonic organ morphogenesis|inner ear development|sensory perception of light stimulus|sensory perception of light stimulus|equilibrioception|pigment granule localization|pigment granule transport|auditory receptor cell stereocilium organization|inner ear receptor cell differentiation|,microfilament motor activity|nucleotide binding|motor activity|actin binding|protein binding|calmodulin binding|ATP binding|protein domain specific binding|spectrin binding|actin-dependent ATPase activity|protein complex binding|protein homodimerization activity|ADP binding|actin filament binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000003420,FCGRT,"Fc receptor, IgG, alpha chain transporter",plasma membrane|membrane|integral component of membrane|,immune response|antigen processing and presentation|Fc-gamma receptor signaling pathway|,IgG binding|beta-2-microglobulin binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000048155,H2BFM,"H2B histone family, member M",nucleosome|nucleus|chromosome|,None,DNA binding|,10,-0.1,0.407,10,0.1,0.199,0,0,0,0.898,0,0,-1.4,1.5
ENSMUSG00000038777,SEMA6C,"sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C",plasma membrane|membrane|integral component of membrane|,multicellular organismal development|nervous system development|axon guidance|cell differentiation|,receptor activity|semaphorin receptor binding|,10,0,0,10,1,1.05,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000038580,SCT,secretin,extracellular region|,visual learning|dentate gyrus development|negative regulation of neuron apoptotic process|neuronal stem cell maintenance|,hormone activity|,10,-0.1,0.0996,10,0.1,0.0753,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000001786,FBXO7,F-box protein 7,ubiquitin ligase complex|nucleus|cytoplasm|mitochondrion|cytosol|protein complex|,mitochondrion degradation|protein targeting to mitochondrion|protein ubiquitination|regulation of protein stability|negative regulation of lymphocyte differentiation|negative regulation of lymphocyte differentiation|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of G1/S transition of mitotic cell cycle|,protein kinase binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000044949,UBTD2,ubiquitin domain containing 2,cytoplasm|,biological_process|,molecular_function|,10,0.6,0.144,10,0.1,0.0503,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000026159,AGFG1,ArfGAP with FG repeats 1,nucleus|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|cell projection|neuronal cell body|intracellular membrane-bounded organelle|,acrosome assembly|transport|multicellular organismal development|spermatogenesis|spermatid nucleus differentiation|cell differentiation|regulation of ARF GTPase activity|intermediate filament organization|,DNA binding|ARF GTPase activator activity|zinc ion binding|metal ion binding|,10,0,0,10,-0.1,0.181,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000031774,FAM192A,"family with sequence similarity 192, member A",nucleus|,biological_process|,molecular_function|,10,0.5,1.53,10,-0.2,0.623,0,0,0,0.898,0,0,-0.9,1.9
ENSMUSG00000070436,SERPINH1,"serine (or cysteine) peptidase inhibitor, clade H, member 1",extracellular space|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|extracellular vesicular exosome|,chondrocyte development involved in endochondral bone morphogenesis|response to stress|negative regulation of endopeptidase activity|regulation of proteolysis|collagen fibril organization|collagen biosynthetic process|protein maturation|,serine-type endopeptidase inhibitor activity|protein binding|poly(A) RNA binding|unfolded protein binding|,10,0,0,10,0.4,0.549,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000033501,CRYGS,"crystallin, gamma S",None,morphogenesis of an epithelium|lens development in camera-type eye|,structural constituent of eye lens|,10,-0.2,0.654,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000026944,ABCA2,"ATP-binding cassette, sub-family A (ABC1), member 2",lysosome|lysosomal membrane|endosome|microtubule organizing center|membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|,ATP catabolic process|regulation of transcription from RNA polymerase II promoter|transport|cholesterol metabolic process|regulation of intracellular cholesterol transport|,nucleotide binding|ATP binding|ATPase activity|,10,0.2,0.705,10,-0.1,0.268,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000020034,TCP11L2,t-complex 11 (mouse) like 2,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.423,10,0,0,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000042073,ABHD14B,abhydrolase domain containing 14b,nucleus|nucleolus|cytoplasm|cytosol|extracellular vesicular exosome|,metabolic process|positive regulation of transcription from RNA polymerase II promoter|,GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,1,2.28,10,0,0,0,0,0,0.898,0,0,-0.7,2
ENSMUSG00000020926,ADAM11,a disintegrin and metallopeptidase domain 11,membrane|integral component of membrane|,proteolysis|integrin-mediated signaling pathway|,metalloendopeptidase activity|protein binding|metallopeptidase activity|zinc ion binding|,10,0.2,0.717,10,-0.1,0.0601,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000036782,KLHL13,kelch-like 13,Cul3-RING ubiquitin ligase complex|,cytokinesis|cell cycle|mitotic nuclear division|protein ubiquitination|cell division|,ubiquitin-protein transferase activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.7,1.4
ENSMUSG00000055193,KLK15,kallikrein related-peptidase 15,None,proteolysis|,peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000053388,TRIM50,tripartite motif-containing 50,intracellular|cytoplasm|aggresome|,regulation of establishment of protein localization|,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.389,10,0,0,0,0,0,0.898,0,0,-1.8,1.2
ENSMUSG00000036545,ADAMTS2,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2",extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|spermatogenesis|protein processing|collagen fibril organization|lung development|collagen catabolic process|skin development|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.5,1.58,10,-0.1,0.183,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000030921,TRIM30A,tripartite motif-containing 30A,intracellular|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|negative regulation of toll-like receptor signaling pathway|positive regulation of protein catabolic process|positive regulation of viral entry into host cell|protein autoubiquitination|negative regulation of NLRP3 inflammasome complex assembly|negative regulation of reactive oxygen species metabolic process|",DNA binding|zinc ion binding|metal ion binding|,10,0,0,10,-0.8,0.871,0,0,0,0.898,0,0,-2,0.8
ENSMUSG00000078484,KLHL17,kelch-like 17,extracellular space|plasma membrane|postsynaptic density|actin cytoskeleton|membrane|cell junction|dendrite cytoplasm|neuronal cell body|synapse|postsynaptic membrane|,actin cytoskeleton organization|,actin binding|POZ domain binding|protein complex scaffold|actin filament binding|,10,0.1,0.117,10,0,0,0,0,0,0.898,0,0,-1.1,1.8
ENSMUSG00000051456,HSPB3,heat shock protein 3,nucleus|cytoplasm|,response to stress|,None,10,0.2,0.531,10,-0.1,0.101,0,0,0,0.898,0,0,-1.5,1.4
ENSMUSG00000028532,CACHD1,cache domain containing 1,cellular_component|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.4,1.7
ENSMUSG00000040009,GNAZ,"guanine nucleotide binding protein, alpha z subunit",cytosol|heterotrimeric G-protein complex|heterotrimeric G-protein complex|plasma membrane|membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|,nucleotide binding|GTPase activity|GTPase activity|signal transducer activity|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|G-protein coupled serotonin receptor binding|G-protein coupled serotonin receptor binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000050428,FBXO46,F-box protein 46,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.215,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000027004,FRZB,frizzled-related protein,extracellular region|extracellular space|extracellular space|cytoplasm|,vasculature development|regulation of transcription from RNA polymerase II promoter|signal transduction|multicellular organismal development|brain development|negative regulation of cell proliferation|gonad development|negative regulation of cell development|Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of cell growth|inner ear morphogenesis|inner ear morphogenesis|positive regulation of apoptotic process|positive regulation of fat cell differentiation|convergent extension involved in organogenesis|mammary gland involution|negative regulation of cartilage development|negative regulation of hepatocyte differentiation|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|cochlea morphogenesis|,protein binding|Wnt-protein binding|Wnt-protein binding|PDZ domain binding|Wnt-activated receptor activity|,9,0.1,0.169,9,0,0,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000031779,CCL22,chemokine (C-C motif) ligand 22,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|,cytokine activity|chemokine activity|,10,-0.4,0.463,10,0,0,0,0,0,0.898,0,0,-2,0.9
ENSMUSG00000042514,KLHL14,kelch-like 14,cytoplasm|endoplasmic reticulum|membrane|neuron projection|neuronal cell body|,biological_process|,protein binding|,10,-0.3,0.352,10,0.1,0.0449,0,0,0,0.898,0,0,-1.8,1.2
ENSMUSG00000037706,CD81,CD81 antigen,immunological synapse|integral component of plasma membrane|membrane|membrane|integral component of membrane|apical plasma membrane|vesicle|extracellular vesicular exosome|,activation of MAPK activity|phosphatidylinositol biosynthetic process|protein localization|positive regulation of cell proliferation|positive regulation of cell growth|positive regulation of B cell proliferation|regulation of cell proliferation|positive regulation of 1-phosphatidylinositol 4-kinase activity|phosphatidylinositol metabolic process|positive regulation of peptidyl-tyrosine phosphorylation|regulation of cell motility|,protein binding|MHC class II protein complex binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000020483,DYNLL2,dynein light chain LC8-type 2,nucleus|cytoplasm|centrosome|cytoskeleton|microtubule|microtubule associated complex|membrane|myosin complex|dynein complex|,transport|microtubule-based process|intracellular transport|,motor activity|protein binding|cytoskeletal protein binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1,2
ENSMUSG00000056812,ST8SIA3,"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,ganglioside biosynthetic process|protein glycosylation|N-glycan processing|glycoprotein metabolic process|oligosaccharide metabolic process|sialylation|sialylation|,"alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.1,0.162,10,0,0,0,0,0,0.898,0,0,-1.3,1.6
ENSMUSG00000063576,KLHDC3,kelch domain containing 3,nuclear chromatin|nuclear chromatin|cytoplasm|cytoplasm|,meiotic nuclear division|biological_process|,chromatin binding|,10,0.2,0.463,10,-0.3,1.19,0,0,0,0.898,0,0,-1.5,1.4
ENSMUSG00000040524,ZFP609,zinc finger protein 609,None,biological_process|,metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000031257,NOX1,NADPH oxidase 1,cytoplasm|endosome|early endosome|plasma membrane|membrane|integral component of membrane|cell junction|cell projection|NADPH oxidase complex|invadopodium membrane|,response to reactive oxygen species|angiogenesis|regulation of systemic arterial blood pressure by renin-angiotensin|superoxide metabolic process|transport|signal transduction|positive regulation of cell proliferation|proton transport|cell migration|extracellular matrix organization|ion transmembrane transport|regulation of ion transmembrane transport|superoxide anion generation|superoxide anion generation|superoxide anion generation|hydrogen peroxide metabolic process|positive regulation of MAPK cascade|positive regulation of integrin biosynthetic process|positive regulation of JNK cascade|positive regulation of smooth muscle cell proliferation|intracellular pH elevation|oxidation-reduction process|oxidation-reduction process|cellular response to hyperoxia|cellular response to acidity|oxygen metabolic process|positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|positive regulation of reactive oxygen species metabolic process|,N-ethylmaleimide reductase activity|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|oxidoreductase activity|voltage-gated proton channel activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|Rac GTPase binding|epoxyqueuosine reductase activity|,10,-0.1,0.062,10,0,0,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000038564,IFT172,intraflagellar transport 172,nucleus|cilium|axoneme|intraciliary transport particle B|motile cilium|ciliary basal body|ciliary basal body|cell projection|sperm midpiece|sperm principal piece|,negative regulation of transcription from RNA polymerase II promoter|neural tube formation|neural tube closure|heart looping|Notch signaling pathway|smoothened signaling pathway|multicellular organismal development|determination of left/right symmetry|brain development|heart development|epidermis development|regulation of smoothened signaling pathway|dorsal/ventral pattern formation|dorsal/ventral pattern formation|protein processing|spinal cord motor neuron differentiation|neural tube development|cytoplasmic microtubule organization|cilium assembly|cilium assembly|positive regulation of smoothened signaling pathway|negative regulation of epithelial cell proliferation|palate development|limb development|cilium morphogenesis|bone development|hindgut development|left/right axis specification|,protein binding|transcription factor binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000007033,HSPA1L,heat shock protein 1-like,zona pellucida receptor complex|cytosol|COP9 signalosome|cell body|blood microparticle|,response to stress|multicellular organismal development|spermatogenesis|binding of sperm to zona pellucida|cell differentiation|protein refolding|,nucleotide binding|ATP binding|unfolded protein binding|,9,0.1,0.153,10,0,0,0,0,0,0.898,0,0,-1.3,1.8
ENSMUSG00000032596,UBA7,ubiquitin-like modifier activating enzyme 7,nucleus|cytosol|,cellular protein modification process|protein ubiquitination|modification-dependent protein catabolic process|ISG15-protein conjugation|ISG15-protein conjugation|,ubiquitin activating enzyme activity|ubiquitin-protein transferase activity|ISG15 activating enzyme activity|ISG15 activating enzyme activity|,10,0,0,10,0.1,0.0665,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000078597,CYP4A12B,"cytochrome P450, family 4, subfamily a, polypeptide 12B",intracellular membrane-bounded organelle|,oxidation-reduction process|,monooxygenase activity|oxidoreductase activity|metal ion binding|,10,0,0,10,0.9,1.32,0,0,0,0.898,0,0,-0.9,2
ENSMUSG00000037108,ZCWPW1,"zinc finger, CW type with PWWP domain 1",cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.1,0.176,10,0,0,0,0,0,0.898,0,0,-0.9,1.9
ENSMUSG00000025092,HSPA12A,heat shock protein 12A,extracellular vesicular exosome|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0.4,1.75,0,0,0,0.898,0,0,-0.7,2
ENSMUSG00000068267,CENPB,centromere protein B,"chromosome, centromeric region|nucleus|chromosome|","regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|chromatin binding|,10,-0.1,0.624,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000001802,LRP3,low density lipoprotein receptor-related protein 3,cellular_component|,biological_process|,protein binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000028494,PLIN2,perilipin 2,nucleus|cytoplasm|lipid particle|lipid particle|cytosol|plasma membrane|membrane|,long-chain fatty acid transport|lipid storage|,protein binding|,10,0,0,10,-0.1,0.405,0,0,0,0.898,0,0,-1.1,2
ENSMUSG00000042501,CPA6,carboxypeptidase A6,cellular_component|extracellular region|proteinaceous extracellular matrix|,proteolysis|,molecular_function|carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000030091,NUP210,nucleoporin 210,nucleus|nuclear envelope|nuclear pore|endoplasmic reticulum|membrane|membrane|integral component of membrane|,transport|protein transport|mRNA transport|,protein dimerization activity|,10,-0.1,0.00444,10,0.2,0.531,0,0,0,0.898,0,0,-1.5,1.4
ENSMUSG00000079056,KCNIP3,"Kv channel interacting protein 3, calsenilin",nucleus|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|cytosol|plasma membrane|membrane|axon|dendrite|protein-DNA complex|axon terminus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transport|ion transport|potassium ion transport|intracellular protein transport|apoptotic process|sensory perception of pain|regulation of ion transmembrane transport|regulation of neuron apoptotic process|negative regulation of transcription, DNA-templated|response to pain|behavioral response to pain|potassium ion transmembrane transport|",DNA binding|voltage-gated ion channel activity|potassium channel activity|calcium ion binding|protein C-terminus binding|potassium channel regulator activity|sequence-specific DNA binding|ion channel binding|metal ion binding|calcium-dependent protein binding|,10,0,0,10,0.1,0.0288,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000041731,PGM5,phosphoglucomutase 5,stress fiber|stress fiber|cytoplasm|cytoskeleton|cell-cell adherens junction|spot adherens junction|spot adherens junction|focal adhesion|focal adhesion|cytoplasmic side of plasma membrane|cytoplasmic side of plasma membrane|intercalated disc|intercalated disc|dystrophin-associated glycoprotein complex|Z disc|cell junction|cell-substrate junction|sarcolemma|sarcolemma|costamere|costamere|,carbohydrate metabolic process|glucose metabolic process|cell adhesion|,magnesium ion binding|protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000090150,ACAD11,"acyl-Coenzyme A dehydrogenase family, member 11",nucleus|mitochondrion|peroxisome|mitochondrial membrane|,metabolic process|fatty acid beta-oxidation using acyl-CoA dehydrogenase|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|long-chain-acyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|transferase activity, transferring phosphorus-containing groups|short-branched-chain-acyl-CoA dehydrogenase activity|very-long-chain-acyl-CoA dehydrogenase activity|4-methyloctanoyl-CoA dehydrogenase activity|naphthyl-2-methyl-succinyl-CoA dehydrogenase activity|2-methylhexanoyl-CoA dehydrogenase activity|propionyl-CoA dehydrogenase activity|thiol-driven fumarate reductase activity|flavin adenine dinucleotide binding|coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity|coenzyme F420-dependent 2,4-dinitrophenol reductase activity|medium-chain-acyl-CoA dehydrogenase activity|",10,0,0,10,0.2,0.198,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000030708,DNAJB13,"DnaJ (Hsp40) related, subfamily B, member 13",None,protein folding|,unfolded protein binding|,10,-0.6,1.65,10,0.1,0.159,0,0,0,0.898,0,0,-2,0.8
ENSMUSG00000038422,HDHD3,haloacid dehalogenase-like hydrolase domain containing 3,mitochondrion|,metabolic process|,hydrolase activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000024338,PSMB8,"proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)",proteasome complex|nucleus|cytoplasm|proteasome core complex|extracellular vesicular exosome|spermatoproteasome complex|,immune system process|proteolysis|antigen processing and presentation|cell differentiation|fat cell differentiation|fat cell differentiation|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,0,0,10,0.3,0.858,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000022097,SFTPC,surfactant associated protein C,extracellular region|extracellular space|cytoplasm|multivesicular body|alveolar lamellar body|,protein homooligomerization|,protein homodimerization activity|,10,0,0,10,0.1,0.259,0,0,0,0.898,0,0,-1.3,1.6
ENSMUSG00000000001,GNAI3,"guanine nucleotide binding protein (G protein), alpha inhibiting 3",cytoplasm|cytoplasm|lysosomal membrane|Golgi apparatus|centrosome|heterotrimeric G-protein complex|heterotrimeric G-protein complex|cytoskeleton|plasma membrane|membrane|midbody|zymogen granule|membrane raft|extracellular vesicular exosome|,GTP catabolic process|vesicle fusion|cell cycle|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|cell division|,nucleotide binding|GTPase activity|GTPase activity|signal transducer activity|protein binding|GTP binding|guanyl nucleotide binding|protein domain specific binding|G-protein beta/gamma-subunit complex binding|G-protein coupled serotonin receptor binding|G-protein coupled serotonin receptor binding|GTPase activating protein binding|metal ion binding|,10,0.1,0.244,10,-0.1,0.0496,0,0,0,0.898,0,0,-1.3,1.6
ENSMUSG00000049657,ZBTB5,zinc finger and BTB domain containing 5,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.1,0.0126,10,0,0,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000062054,IAH1,isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae),extracellular vesicular exosome|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|nuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.7,1.4
ENSMUSG00000080115,METTL21B,N/A,None,None,None,10,-0.1,0.233,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000040715,RSC1A1,"regulatory solute carrier protein, family 1, member 1",nucleus|Golgi apparatus|plasma membrane|brush border|membrane|cell junction|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|intestinal absorption|negative regulation of transport|",protein binding|,10,0,0,10,-0.8,0.562,0,0,0,0.898,0,0,-2,0.8
ENSMUSG00000005312,UBQLN1,ubiquilin 1,proteasome complex|nucleus|cytoplasm|endoplasmic reticulum|protein complex|perinuclear region of cytoplasm|,regulation of protein ubiquitination|response to endoplasmic reticulum stress|cellular response to hypoxia|regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,receptor binding|intermediate filament binding|kinase binding|protein domain specific binding|,10,0.2,0.308,10,-0.2,0.26,0,0,0,0.898,0,0,-1.9,1
ENSMUSG00000055489,ANO5,anoctamin 5,intracellular|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|vesicle|,chloride transport|chloride transmembrane transport|,None,10,0,0,10,-0.3,1.62,0,0,0,0.898,0,0,-1.5,1.3
ENSMUSG00000032014,OAF,OAF homolog (Drosophila),extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0.5,1.37,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000029371,CXCL5,chemokine (C-X-C motif) ligand 5,extracellular region|extracellular space|,leukocyte homeostasis|cytokine production|chemotaxis|inflammatory response|immune response|positive regulation of neuron projection development|organ regeneration|response to lipopolysaccharide|regulation of chemokine production|positive regulation of JAK-STAT cascade|cell chemotaxis|regulation of neutrophil mediated killing of gram-negative bacterium|,cytokine activity|chemokine activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.1,2
ENSMUSG00000030685,KCTD13,potassium channel tetramerisation domain containing 13,nucleus|Cul3-RING ubiquitin ligase complex|,DNA replication|cell migration|protein ubiquitination|negative regulation of Rho protein signal transduction|stress fiber assembly|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of DNA replication|protein homooligomerization|,ubiquitin-protein transferase activity|GTP-Rho binding|protein domain specific binding|identical protein binding|,10,0.1,0.00222,10,-0.1,0.093,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000033533,ACSM1,acyl-CoA synthetase medium-chain family member 1,mitochondrion|mitochondrial matrix|mitochondrial matrix|extracellular vesicular exosome|blood microparticle|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|metabolic process|,nucleotide binding|catalytic activity|acyl-CoA ligase activity|acyl-CoA ligase activity|ATP binding|GTP binding|fatty acid ligase activity|ligase activity|metal ion binding|butyrate-CoA ligase activity|butyrate-CoA ligase activity|,10,0.9,0.205,10,0.2,0.0287,0,0,0,0.898,0,0,-0.7,2
ENSMUSG00000021319,SFRP4,secreted frizzled-related protein 4,extracellular region|extracellular space|extracellular space|nucleus|cytoplasm|cytoplasm|cell surface|,vasculature development|positive regulation of receptor internalization|regulation of transcription from RNA polymerase II promoter|signal transduction|multicellular organismal development|brain development|negative regulation of cell proliferation|gonad development|embryo development|positive regulation of gene expression|Wnt signaling pathway|cell differentiation|positive regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of epidermal cell differentiation|negative regulation of JNK cascade|negative regulation of JNK cascade|decidualization|phosphate ion homeostasis|mammary gland involution|epithelium development|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|positive regulation of keratinocyte apoptotic process|negative regulation of sodium-dependent phosphate transport|,Wnt-protein binding|Wnt-protein binding|PDZ domain binding|Wnt-activated receptor activity|,9,0,0,9,-0.1,0.116,0,0,0,0.898,0,0,-1.9,1.2
ENSMUSG00000047496,RNF152,ring finger protein 152,lysosome|membrane|integral component of membrane|,apoptotic process|protein K48-linked ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000004642,SLBP,stem-loop binding protein,nucleus|nucleus|cytoplasm|cytoplasm|ribonucleoprotein complex|histone pre-mRNA 3'end processing complex|,mRNA processing|histone mRNA 3'-end processing|nuclear cell cycle DNA replication|mRNA transport|,RNA binding|mRNA binding|mRNA binding|poly(A) RNA binding|histone pre-mRNA stem-loop binding|,9,0,0,9,-0.2,0.451,0,0,0,0.898,0,0,-1.9,1.1
ENSMUSG00000079608,STARD6,StAR-related lipid transfer (START) domain containing 6,cellular_component|,transport|lipid transport|biological_process|,lipid binding|cholesterol binding|,10,0.1,0.0507,10,0,0,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000066361,SERPINA3C,"serine (or cysteine) peptidase inhibitor, clade A, member 3C",extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.1,0.0359,10,-0.1,0.248,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000059213,DDN,dendrin,nucleus|cytoplasm|endoplasmic reticulum|plasma membrane|membrane|dendrite|cell projection|,transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|,RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.3
ENSMUSG00000020877,SCRN2,secernin 2,extracellular vesicular exosome|,proteolysis|biological_process|,molecular_function|dipeptidase activity|,10,0,0,10,-0.1,0.0501,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000019944,RHOBTB1,Rho-related BTB domain containing 1,cellular_component|intracellular|,small GTPase mediated signal transduction|,nucleotide binding|protein binding|GTP binding|,10,0,0,10,1.2,0.744,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000025232,HEXA,hexosaminidase A,lysosome|membrane|membrane|extracellular vesicular exosome|,skeletal system development|carbohydrate metabolic process|ganglioside catabolic process|lysosome organization|lysosome organization|sensory perception of sound|locomotory behavior|adult walking behavior|metabolic process|lipid storage|sexual reproduction|glycosaminoglycan metabolic process|myelination|cell morphogenesis involved in neuron differentiation|neuromuscular process controlling posture|neuromuscular process controlling balance|SMAD protein signal transduction|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-N-acetylhexosaminidase activity|beta-N-acetylhexosaminidase activity|beta-N-acetylhexosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|protein heterodimerization activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1,2
ENSMUSG00000010122,SLC47A1,"solute carrier family 47, member 1",plasma membrane|membrane|integral component of membrane|membrane-bounded vesicle|,transport|drug transmembrane transport|organic cation transport|drug transport|transmembrane transport|hydrogen ion transmembrane transport|,monovalent cation:proton antiporter activity|drug transmembrane transporter activity|antiporter activity|,10,0,0,10,-0.1,0.401,0,0,0,0.898,0,0,-1.3,1.8
ENSMUSG00000015340,CYBB,"cytochrome b-245, beta polypeptide",intracellular|cytoplasm|mitochondrion|endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|dendrite|NADPH oxidase complex|NADPH oxidase complex|neuronal cell body|,superoxide metabolic process|superoxide metabolic process|transport|ion transport|inflammatory response|regulation of ion transmembrane transport|response to drug|superoxide anion generation|innate immune response|respiratory burst|hydrogen peroxide biosynthetic process|oxidation-reduction process|oxidation-reduction process|,voltage-gated ion channel activity|protein binding|N-ethylmaleimide reductase activity|electron carrier activity|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|oxidoreductase activity|heme binding|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|protein heterodimerization activity|flavin adenine dinucleotide binding|epoxyqueuosine reductase activity|,10,-0.6,0.839,10,0,0,0,0,0,0.898,0,0,-2,0.9
ENSMUSG00000031384,ASB9,ankyrin repeat and SOCS box-containing 9,mitochondrion|,protein ubiquitination|intracellular signal transduction|positive regulation of protein catabolic process|,protein binding|,10,0.7,0.842,10,-0.1,0.0886,0,0,0,0.898,0,0,-0.6,2
ENSMUSG00000055951,CCL25,chemokine (C-C motif) ligand 25,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|leukocyte migration|cell chemotaxis|,cytokine activity|protein binding|chemokine activity|CCR10 chemokine receptor binding|chemokine receptor binding|,10,0,0,10,-0.2,0.634,0,0,0,0.898,0,0,-1.4,1.5
ENSMUSG00000023845,LNPEP,leucyl/cystinyl aminopeptidase,intracellular|lysosomal membrane|plasma membrane|membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,proteolysis|protein catabolic process|SMAD protein signal transduction|,aminopeptidase activity|aminopeptidase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000033781,ASB13,ankyrin repeat and SOCS box-containing 13,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000041058,WWP1,WW domain containing E3 ubiquitin protein ligase 1,nucleus|cytoplasm|plasma membrane|membrane|,"protein ubiquitination|protein ubiquitination|T cell differentiation|lung development|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of transcription, DNA-templated|","ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.221,10,0,0,0,0,0,0.898,0,0,-1.9,1
ENSMUSG00000048528,NKX1-2,"NK1 transcription factor related, locus 2 (Drosophila)",cellular_component|nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|",DNA binding|protein binding|sequence-specific DNA binding|,10,0,0,10,0.2,0.0963,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000032507,FBXL2,F-box and leucine-rich repeat protein 2,membrane|,ubiquitin-dependent protein catabolic process|protein monoubiquitination|protein monoubiquitination|,ubiquitin-protein transferase activity|protein binding|calmodulin binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000024743,SYT7,synaptotagmin VII,lysosome|synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,plasma membrane repair|transport|exocytosis|,transporter activity|metal ion binding|,10,0,0,10,0.1,0.111,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000006269,ATP6V1B1,"ATPase, H+ transporting, lysosomal V1 subunit B1",cytoplasm|cytosol|microvillus|membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|lateral plasma membrane|vacuolar proton-transporting V-type ATPase complex|vacuolar proton-transporting V-type ATPase complex|extracellular vesicular exosome|,ossification|ossification|transport|ion transport|regulation of pH|regulation of pH|excretion|excretion|sensory perception of sound|proton transport|proton transport|pH reduction|pH reduction|calcium ion homeostasis|calcium ion homeostasis|hydrogen ion transmembrane transport|,hydrogen ion transmembrane transporter activity|protein complex binding|,10,0.9,1.59,10,0,0,0,0,0,0.898,0,0,-0.6,2
ENSMUSG00000034088,HDLBP,high density lipoprotein (HDL) binding protein,nucleus|cytoplasm|high-density lipoprotein particle|,lipid metabolic process|transport|lipid transport|biological_process|steroid metabolic process|cholesterol metabolic process|,RNA binding|poly(A) RNA binding|,10,0.1,0.538,10,0,0,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000021458,2010111I01RIK,RIKEN cDNA 2010111I01 gene,nucleolus|cytoplasm|,proteolysis|proteolysis|leukotriene biosynthetic process|,aminopeptidase activity|aminopeptidase activity|peptidase activity|metallopeptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.6,0.279,10,0,0,0,0,0,0.898,0,0,-2,0.9
ENSMUSG00000026470,STX6,syntaxin 6,early endosome|Golgi apparatus|Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|integral component of membrane|SNARE complex|SNARE complex|trans-Golgi network membrane|trans-Golgi network membrane|perinuclear region of cytoplasm|recycling endosome|,"transport|intracellular protein transport|vesicle fusion|vesicle fusion|endosome organization|protein transport|vesicle-mediated transport|retrograde transport, endosome to Golgi|retrograde transport, endosome to Golgi|Golgi vesicle transport|",SNAP receptor activity|protein binding|,10,-0.2,0.153,10,0.4,1.22,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000084174,SYCN,syncollin,membrane|secretory granule membrane|cytoplasmic vesicle|,exocytosis|,None,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000004613,LIM2,lens intrinsic membrane protein 2,plasma membrane|tight junction|membrane|integral component of membrane|vesicle|,lens development in camera-type eye|camera-type eye development|,structural constituent of eye lens|,10,0,0,10,-0.1,0.289,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000038255,NEUROD2,neurogenic differentiation 2,nucleus|,"behavioral fear response|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|associative learning|protein ubiquitination|cerebellar cortex development|cell differentiation|positive regulation of synaptic plasticity|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|neuron development|positive regulation of calcium-mediated signaling|positive regulation of sequence-specific DNA binding transcription factor activity|cellular response to electrical stimulus|cellular response to calcium ion|positive regulation of synapse maturation|negative regulation of synapse maturation|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|transcription corepressor activity|protein binding|protein heterodimerization activity|protein dimerization activity|E-box binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000046404,YOD1,YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae),None,proteolysis|response to unfolded protein|ER-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum unfolded protein response|protein K29-linked deubiquitination|protein K11-linked deubiquitination|protein K63-linked deubiquitination|protein K48-linked deubiquitination|protein K27-linked deubiquitination|protein K33-linked deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|Lys48-specific deubiquitinase activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.3,1.8
ENSMUSG00000025582,NPTX1,neuronal pentraxin 1,cytoplasm|mitochondrion|plasma membrane|cytoplasmic vesicle|neuron projection|,mitochondrial transport|cellular response to potassium ion|mitochondrial fragmentation involved in apoptotic process|axonogenesis involved in innervation|,metal ion binding|,10,0,0,10,-0.3,1.03,0,0,0,0.898,0,0,-2,0.9
ENSMUSG00000006651,APLP1,amyloid beta (A4) precursor-like protein 1,cytoplasm|Golgi apparatus|plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,mRNA polyadenylation|regulation of translation|endocytosis|apoptotic process|cell adhesion|cell death|extracellular matrix organization|negative regulation of cAMP biosynthetic process|forebrain development|cellular response to norepinephrine stimulus|,protein binding|heparin binding|alpha-2A adrenergic receptor binding|alpha-2B adrenergic receptor binding|alpha-2C adrenergic receptor binding|identical protein binding|metal ion binding|transition metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000034872,GIPC3,"GIPC PDZ domain containing family, member 3",cellular_component|,biological_process|,None,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.8,1.4
ENSMUSG00000078096,GOLGB1,"golgi autoantigen, golgin subfamily b, macrogolgin 1",endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|Golgi apparatus|cis-Golgi network|membrane|,biological_process|,poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.4,1.7
ENSMUSG00000039873,NEURL2,neuralized-like 2 (Drosophila),cytoplasm|muscle tendon junction|VCB complex|,myofibril assembly|intracellular signal transduction|sarcomere organization|,protein binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000096262,AP1G1,"adaptor protein complex AP-1, gamma 1 subunit",cytoplasm|Golgi apparatus|trans-Golgi network|trans-Golgi network|cytosol|microtubule cytoskeleton|membrane|membrane|membrane coat|clathrin adaptor complex|clathrin-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|recycling endosome|,microtubule cytoskeleton organization|transport|intracellular protein transport|protein transport|vesicle-mediated transport|endosome to melanosome transport|positive regulation of natural killer cell degranulation|positive regulation of natural killer cell mediated cytotoxicity|Golgi to lysosome transport|,protein binding|collagen binding|protein C-terminus binding|protein transporter activity|Rab GTPase binding|kinesin binding|GTP-dependent protein binding|,3,0,0,3,0,0,0,0,0,0.898,0,0,-1.9,1.7
ENSMUSG00000093639,LIM2,lens intrinsic membrane protein 2,plasma membrane|tight junction|membrane|integral component of membrane|vesicle|,lens development in camera-type eye|camera-type eye development|,structural constituent of eye lens|,10,0,0,10,-0.2,0.625,0,0,0,0.898,0,0,-1.2,1.7
ENSMUSG00000029860,ZYX,zyxin,stress fiber|nucleus|cytoplasm|cytoskeleton|cell-cell adherens junction|focal adhesion|cell junction|,cell adhesion|,protein binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.8,1.2
ENSMUSG00000042734,TTC9,tetratricopeptide repeat domain 9,endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|,10,0.1,0.0689,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000040410,FBXL4,F-box and leucine-rich repeat protein 4,nucleus|cytoplasm|mitochondrion|mitochondrial intermembrane space|,biological_process|,molecular_function|,10,-0.1,0.238,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000036492,RNF39,ring finger protein 39,None,None,metal ion binding|,10,0,0,10,-0.2,0.488,0,0,0,0.898,0,0,-1.7,1.2
ENSMUSG00000031788,KIFC3,kinesin family member C3,cytoplasm|Golgi apparatus|centrosome|cytoskeleton|kinesin complex|microtubule|zonula adherens|membrane|cell junction|cytoplasmic vesicle|extracellular vesicular exosome|,microtubule-based process|microtubule-based movement|Golgi organization|zonula adherens maintenance|epithelial cell-cell adhesion|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|minus-end-directed microtubule motor activity|,10,0,0,10,0.1,0.153,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000017756,SLC12A7,"solute carrier family 12, member 7",plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|cell volume homeostasis|transmembrane transport|,symporter activity|cation:chloride symporter activity|potassium:chloride symporter activity|protein kinase binding|,10,0.1,0.056,10,-0.1,0.0625,0,0,0,0.898,0,0,-1.1,1.9
ENSMUSG00000038527,C1RL,"complement component 1, r subcomponent-like",extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|,"immune system process|proteolysis|complement activation, classical pathway|innate immune response|",catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.255,10,-1,1.39,0,0,0,0.898,0,0,-2,0.8
ENSMUSG00000034783,CD207,CD207 antigen,integral component of plasma membrane|membrane|integral component of membrane|,defense response to virus|,carbohydrate binding|carbohydrate binding|,10,0,0,10,0.3,0.0247,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000030323,IFT122,intraflagellar transport 122,intracellular|cell|cytoplasm|cytoplasm|cytoskeleton|cilium|membrane|intraciliary transport particle A|intraciliary transport particle A|photoreceptor connecting cilium|ciliary basal body|cell projection|primary cilium|,neural tube closure|signal transduction downstream of smoothened|multicellular organismal development|dorsal/ventral pattern formation|dorsal/ventral pattern formation|embryonic body morphogenesis|negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning|cell projection organization|embryonic heart tube development|embryonic forelimb morphogenesis|intraciliary anterograde transport|intraciliary retrograde transport|embryonic digit morphogenesis|negative regulation of smoothened signaling pathway|camera-type eye morphogenesis|negative regulation of epithelial cell proliferation|limb development|cilium morphogenesis|cilium morphogenesis|ciliary receptor clustering involved in smoothened signaling pathway|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|embryonic heart tube left/right pattern formation|protein localization to cilium|establishment of protein localization to organelle|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-2,1
ENSMUSG00000044982,SFT2D3,SFT2 domain containing 3,cellular_component|membrane|integral component of membrane|,transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|,10,0.1,0.132,10,-0.1,0.0699,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000030811,FBXL19,F-box and leucine-rich repeat protein 19,SCF ubiquitin ligase complex|,proteasome-mediated ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|,DNA binding|protein binding|zinc ion binding|metal ion binding|,10,0.1,0.238,10,0,0,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000026574,DPT,dermatopontin,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|extracellular vesicular exosome|,cell adhesion|negative regulation of cell proliferation|collagen fibril organization|,molecular_function|,10,-0.8,0.0656,10,-0.3,0.208,0,0,0,0.898,0,0,-2,0.7
ENSMUSG00000029474,RNF34,ring finger protein 34,nucleus|cytoplasm|plasma membrane|membrane|,apoptotic process|protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|phosphatidylinositol phosphate binding|",10,0,0,10,0,0,0,0,0,0.898,0,0,-0.7,2
ENSMUSG00000042670,IMMP1L,IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae),mitochondrion|mitochondrial inner membrane|membrane|,proteolysis|protein processing involved in protein targeting to mitochondrion|biological_process|,molecular_function|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,0.1,0.0307,9,0,0,0,0,0,0.898,0,0,-1.4,1.7
ENSMUSG00000034825,NRIP3,nuclear receptor interacting protein 3,cellular_component|,proteolysis|biological_process|,aspartic-type endopeptidase activity|,10,-0.4,1.38,10,0.1,0.0137,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000021846,PELI2,pellino 2,cytosol|membrane|protein complex|,positive regulation of protein phosphorylation|Toll signaling pathway|positive regulation of MAPK cascade|,"protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000012396,NANOG,Nanog homeobox,nucleus|nucleus|nucleoplasm|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|mesodermal cell fate commitment|endodermal cell fate specification|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell proliferation|positive regulation of cell proliferation|embryo development|response to organic substance|negative regulation of cell fate commitment|negative regulation of cell fate commitment|regulation of gene expression|stem cell division|stem cell maintenance|stem cell maintenance|negative regulation of BMP signaling pathway|response to retinoic acid|somatic stem cell maintenance|negative regulation of endodermal cell fate specification|regulation of cell differentiation|negative regulation of cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|stem cell differentiation|stem cell differentiation|",enhancer sequence-specific DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,-0.1,0.0167,10,0,0,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000050148,UBQLN2,ubiquilin 2,nucleus|cytoplasm|plasma membrane|membrane|,None,protein binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000053769,LYSMD1,"LysM, putative peptidoglycan-binding, domain containing 1",cellular_component|,biological_process|,molecular_function|,6,0,0,6,0,0,0,0,0,0.898,0,0,-1.8,1.6
ENSMUSG00000032948,LIPI,"lipase, member I",extracellular space|plasma membrane|,lipid catabolic process|,phospholipase activity|heparin binding|,7,0,0,7,0,0,0,0,0,0.898,0,0,-1.8,1.5
ENSMUSG00000020130,TBC1D15,"TBC1 domain family, member 15",extracellular region|cytoplasm|mitochondrion|extracellular vesicular exosome|,regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|,GTPase activator activity|Rab GTPase activator activity|,10,0,0,10,-0.1,0.134,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000025921,RDH10,retinol dehydrogenase 10 (all-trans),cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|cell body|,metanephros development|in utero embryonic development|retinoic acid biosynthetic process|visual perception|metabolic process|gonad development|organ morphogenesis|neural crest cell development|embryonic camera-type eye development|embryonic forelimb morphogenesis|retinol metabolic process|retinal metabolic process|ear development|nose development|embryonic organ development|embryonic viscerocranium morphogenesis|oxidation-reduction process|primary lung bud formation|bud elongation involved in lung branching|,retinol dehydrogenase activity|retinol dehydrogenase activity|retinol dehydrogenase activity|oxidoreductase activity|NADP-retinol dehydrogenase activity|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000031748,GNAO1,"guanine nucleotide binding protein, alpha O",intracellular|heterotrimeric G-protein complex|heterotrimeric G-protein complex|plasma membrane|membrane|membrane|neuron projection|protein complex|,GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|dopamine receptor signaling pathway|aging|locomotory behavior|regulation of heart contraction|cellular process|response to organonitrogen compound|positive regulation of GTPase activity|negative regulation of calcium ion transport|,nucleotide binding|GTPase activity|GTPase activity|GTPase activity|signal transducer activity|protein binding|GTP binding|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|G-protein coupled serotonin receptor binding|G-protein coupled serotonin receptor binding|mu-type opioid receptor binding|mu-type opioid receptor binding|protein complex binding|GTPase activating protein binding|metal ion binding|corticotropin-releasing hormone receptor 1 binding|corticotropin-releasing hormone receptor 1 binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000047631,APOF,apolipoprotein F,cellular_component|extracellular region|low-density lipoprotein particle|high-density lipoprotein particle|,lipid metabolic process|triglyceride metabolic process|transport|lipid transport|steroid metabolic process|cholesterol metabolic process|cholesterol efflux|,molecular_function|,10,0.2,0.922,10,0,0,0,0,0,0.898,0,0,-1.4,1.5
ENSMUSG00000027163,COMMD9,COMM domain containing 9,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.153,0,0,0,0.898,0,0,-1.7,1.4
ENSMUSG00000027072,PRG3,proteoglycan 3,None,histamine biosynthetic process|immune response|negative regulation of translation|leukotriene biosynthetic process|neutrophil activation|superoxide anion generation|positive regulation of interleukin-8 biosynthetic process|basophil activation|,carbohydrate binding|,10,0,0,10,-0.1,0.0164,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000019188,H13,histocompatibility 13,endoplasmic reticulum|endoplasmic reticulum membrane|rough endoplasmic reticulum|plasma membrane|cell surface|membrane|membrane|integral component of membrane|integral component of cytoplasmic side of endoplasmic reticulum membrane|integral component of lumenal side of endoplasmic reticulum membrane|,proteolysis|membrane protein proteolysis|,"aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|protein homodimerization activity|",10,0,0,10,1,1.21,0,0,0,0.898,0,0,-0.7,2
ENSMUSG00000005986,ANKRD13D,"ankyrin repeat domain 13 family, member D",cellular_component|endosome|plasma membrane|membrane|,biological_process|,molecular_function|,10,-0.1,0.595,10,0.1,0.252,0,0,0,0.898,0,0,-1.4,1.5
ENSMUSG00000034377,TULP4,tubby like protein 4,cytoplasm|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.4,1.7
ENSMUSG00000047797,GJB1,"gap junction protein, beta 1",cytoplasm|endoplasmic reticulum|plasma membrane|plasma membrane|gap junction|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,cell communication|purine ribonucleotide transport|protein oligomerization|transmembrane transport|,gap junction channel activity|protein homodimerization activity|,10,-0.1,0.413,10,0,0,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000054277,ARFGAP3,ADP-ribosylation factor GTPase activating protein 3,cytoplasm|Golgi apparatus|cytosol|membrane|membrane|,transport|protein transport|vesicle-mediated transport|regulation of ARF GTPase activity|positive regulation of GTPase activity|,GTPase activator activity|ARF GTPase activator activity|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-1.7,1.4
ENSMUSG00000025219,FGF8,fibroblast growth factor 8,extracellular region|extracellular space|intracellular|external side of plasma membrane|,MAPK cascade|patterning of blood vessels|branching involved in ureteric bud morphogenesis|organ induction|kidney development|neural plate morphogenesis|heart looping|blood vessel remodeling|heart morphogenesis|outflow tract septum morphogenesis|outflow tract morphogenesis|epithelial to mesenchymal transition involved in endocardial cushion formation|epithelial to mesenchymal transition involved in endocardial cushion formation|apoptotic process|response to oxidative stress|multicellular organismal development|determination of left/right symmetry|heart development|motor neuron axon guidance|mesodermal cell migration|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|gonad development|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|embryo development ending in birth or egg hatching|positive regulation of gene expression|positive regulation of gene expression|positive regulation of gene expression|telencephalon development|pallium development|subpallium development|forebrain dorsal/ventral pattern formation|cell proliferation in forebrain|forebrain neuron development|central nervous system neuron development|signal transduction involved in regulation of gene expression|cell differentiation|lung development|BMP signaling pathway|male genitalia development|thyroid gland development|thyroid gland development|otic vesicle formation|midbrain-hindbrain boundary development|dorsal/ventral axon guidance|embryonic heart tube development|limb morphogenesis|embryonic hindlimb morphogenesis|aorta morphogenesis|inner ear morphogenesis|regulation of odontogenesis of dentin-containing tooth|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|cell fate commitment|positive regulation of mitosis|positive regulation of organ growth|positive regulation of organ growth|generation of neurons|forebrain morphogenesis|positive chemotaxis|positive regulation of cell division|negative regulation of cardiac muscle tissue development|pharyngeal system development|canonical Wnt signaling pathway|corticotropin hormone secreting cell differentiation|thyroid-stimulating hormone-secreting cell differentiation|bone development|lung morphogenesis|branching involved in salivary gland morphogenesis|branching involved in salivary gland morphogenesis|neuroepithelial cell differentiation|dopaminergic neuron differentiation|cell migration involved in mesendoderm migration|,receptor binding|fibroblast growth factor receptor binding|type 1 fibroblast growth factor receptor binding|type 2 fibroblast growth factor receptor binding|growth factor activity|chemoattractant activity|,10,0,0,10,-0.1,0.251,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000040952,RPS19,ribosomal protein S19,intracellular|nucleolus|cytoplasm|cytosol|ribosome|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,"ribosomal small subunit assembly|maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|monocyte chemotaxis|rRNA processing|translation|nucleolus organization|erythrocyte differentiation|maturation of SSU-rRNA|ribosomal small subunit biogenesis|protein tetramerization|positive regulation of respiratory burst involved in inflammatory response|negative regulation of respiratory burst involved in inflammatory response|",structural constituent of ribosome|fibroblast growth factor binding|protein kinase binding|translation initiation factor binding|protein homodimerization activity|poly(A) RNA binding|,8,0,0,9,0,0,0,0,0,0.898,0,0,-1.3,1.8
ENSMUSG00000040907,ATP1A3,"ATPase, Na+/K+ transporting, alpha 3 polypeptide",nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|sodium:potassium-exchanging ATPase complex|membrane|integral component of membrane|axon|myelin sheath|dendritic spine neck|dendritic spine head|synapse|,ATP catabolic process|ATP biosynthetic process|transport|ion transport|cation transport|potassium ion transport|sodium ion transport|memory|adult locomotory behavior|visual learning|monovalent inorganic cation transport|ionotropic glutamate receptor signaling pathway|sodium ion transmembrane transport|response to drug|potassium ion transmembrane transport|,"nucleotide binding|sodium:potassium-exchanging ATPase activity|ATP binding|monovalent inorganic cation transmembrane transporter activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|cation-transporting ATPase activity|D1 dopamine receptor binding|metal ion binding|",10,0.1,0.292,9,-0.2,0.675,0,0,0,0.898,0,0,-2,0.9
ENSMUSG00000024481,4833403I15RIK,RIKEN cDNA 4833403I15 gene,cellular_component|membrane|integral component of membrane|,proteolysis|biological_process|,molecular_function|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,1.4,0.196,10,0,0,0,0,0,0.898,0,0,-1.3,2
ENSMUSG00000050296,ABCA12,"ATP-binding cassette, sub-family A (ABC1), member 12",cytoplasm|mitochondrial inner membrane|cytosol|plasma membrane|epidermal lamellar body|,lipid transport|positive regulation of cholesterol efflux|positive regulation of cholesterol efflux|positive regulation of cholesterol efflux|keratinocyte differentiation|keratinization|secretion by cell|phospholipid efflux|ceramide transport|surfactant homeostasis|regulated secretory pathway|lung alveolus development|lipid homeostasis|establishment of skin barrier|protein localization to plasma membrane|positive regulation of protein localization to cell surface|,nucleotide binding|receptor binding|lipid transporter activity|protein binding|ATP binding|apolipoprotein A-I receptor binding|,9,0,0,9,-0.3,0.409,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000054206,GZMM,granzyme M (lymphocyte met-ase 1),membrane|,proteolysis|cytolysis|,endopeptidase activity|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.264,10,0,0,0,0,0,0.898,0,0,-1.6,1.5
ENSMUSG00000063802,HSPBP1,"HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1",cellular_component|,positive regulation of protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|,molecular_function|,10,-0.3,1.11,10,0,0,0,0,0,0.898,0,0,-1.5,1.3
ENSMUSG00000025226,FBXL15,F-box and leucine-rich repeat protein 15,cytoplasm|SCF ubiquitin ligase complex|,G2/M transition of mitotic cell cycle|protein ubiquitination|bone mineralization|positive regulation of BMP signaling pathway|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|,ubiquitin-protein transferase activity|,10,0.3,0.723,10,0,0,0,0,0,0.898,0,0,-1,1.8
ENSMUSG00000056260,LRIF1,ligand dependent nuclear receptor interacting factor 1,nucleus|actin cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|retinoic acid receptor binding|,9,0,0,10,0.3,0.179,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000020732,RAB37,"RAB37, member RAS oncogene family",endoplasmic reticulum-Golgi intermediate compartment|secretory granule|cytoplasmic vesicle|,GTP catabolic process|transport|small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTPase activity|protein binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.898,0,0,-2,1.1
ENSMUSG00000042099,KANK3,KN motif and ankyrin repeat domains 3,cytoplasm|,negative regulation of stress fiber assembly|,molecular_function|,10,0,0,10,-0.1,0.182,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000033272,SLC35A4,"solute carrier family 35, member A4",Golgi membrane|cellular_component|Golgi apparatus|membrane|integral component of membrane|,transport|biological_process|carbohydrate transport|,molecular_function|sugar:proton symporter activity|,10,0.4,1.13,9,0,0,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000000120,NGFR,"nerve growth factor receptor (TNFR superfamily, member 16)",intracellular|cell|nucleus|nuclear envelope|cytoplasm|cytoplasm|rough endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|coated vesicle|dendrite membrane|neuronal cell body membrane|perikaryon|membrane raft|clathrin-coated endocytic vesicle|neuronal postsynaptic density|,"intracellular protein transport|apoptotic process|signal transduction|signal transduction|multicellular organismal development|nervous system development|axon guidance|central nervous system development|response to wounding|regulation of gene expression|positive regulation of cell death|negative regulation of neuron projection development|programmed cell death|detection of temperature stimulus|sensory perception of pain|nerve development|cell differentiation|hair follicle morphogenesis|positive regulation of myelination|positive regulation of synaptic transmission, cholinergic|circadian regulation of gene expression|cellular response to oxidative stress|positive regulation of Rho protein signal transduction|negative regulation of fibroblast growth factor receptor signaling pathway|positive regulation of odontogenesis of dentin-containing tooth|glucose homeostasis|positive regulation of apoptotic process|positive regulation of MAPK cascade|negative regulation of neuron apoptotic process|skin development|positive regulation of fibroblast proliferation|rhythmic process|negative regulation of hair follicle development|positive regulation of protein kinase B signaling|negative regulation of mitochondrial depolarization|positive regulation of synaptic transmission, glutamatergic|negative regulation of cell death|positive regulation of neuron death|regulation of reactive oxygen species metabolic process|positive regulation of apoptotic signaling pathway|regulation of glucose import in response to insulin stimulus|",beta-amyloid binding|death receptor activity|neurotrophin TRKA receptor binding|protein binding|Rab GTPase binding|ubiquitin protein ligase binding|neurotrophin binding|nerve growth factor binding|nerve growth factor binding|preprotein binding|,10,0,0,10,0.1,0.0382,0,0,0,0.898,0,0,-1.1,1.8
ENSMUSG00000042213,ZFAND4,"zinc finger, AN1-type domain 4",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.252,10,0.1,0.21,0,0,0,0.898,0,0,-1.5,1.5
ENSMUSG00000033343,MAGEA4,"melanoma antigen, family A, 4",nucleus|cytoplasm|,biological_process|,molecular_function|,10,-0.2,0.536,10,0,0,0,0,0,0.898,0,0,-1.2,1.8
ENSMUSG00000030218,MGP,matrix Gla protein,extracellular region|extracellular space|endoplasmic reticulum|extracellular matrix|extracellular matrix|protein complex|extracellular vesicular exosome|,ossification|protein complex assembly|multicellular organismal development|cell differentiation|lung development|regulation of bone mineralization|branching morphogenesis of an epithelial tube|cartilage development|,calcium ion binding|calcium-dependent protein binding|,10,-0.1,0.123,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000073433,ARHGDIG,Rho GDP dissociation inhibitor (GDI) gamma,cytoplasm|membrane|,regulation of protein localization|regulation of catalytic activity|,small GTPase regulator activity|GDP-dissociation inhibitor activity|Rho GDP-dissociation inhibitor activity|GTPase activator activity|protein binding|,10,0,0,10,-0.1,0.0816,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000027364,USP50,ubiquitin specific peptidase 50,cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0.3,0.367,10,-1,2.16,0,0,0,0.898,0,0,-2,1.1
ENSMUSG00000021676,IQGAP2,IQ motif containing GTPase activating protein 2,intracellular|microtubule|microvillus|extracellular vesicular exosome|,signal transduction|small GTPase mediated signal transduction|regulation of small GTPase mediated signal transduction|,"GTPase activator activity|Ras GTPase activator activity|calmodulin binding|phosphatidylinositol-3,4,5-trisphosphate binding|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.4,1.7
ENSMUSG00000074895,EIF4E1B,eukaryotic translation initiation factor 4E family member 1B,cytoplasm|,translation|translational initiation|,RNA binding|translation initiation factor activity|,9,0.2,0.99,9,0,0,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000055675,KBTBD11,kelch repeat and BTB (POZ) domain containing 11,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0836,0,0,0,0.898,0,0,-1.5,1.7
ENSMUSG00000061353,CXCL12,chemokine (C-X-C motif) ligand 12,extracellular region|extracellular space|plasma membrane|external side of plasma membrane|extracellular vesicular exosome|,patterning of blood vessels|ameboidal cell migration|neuron migration|positive regulation of endothelial cell proliferation|chemotaxis|immune response|germ cell development|brain development|motor neuron axon guidance|positive regulation of cell proliferation|adult locomotory behavior|germ cell migration|telencephalon cell migration|regulation of cell migration|regulation of cell migration|positive regulation of cell migration|positive regulation of cell migration|organ regeneration|positive regulation of dopamine secretion|T cell proliferation|positive regulation of neuron differentiation|positive regulation of cell adhesion|positive regulation of axon extension involved in axon guidance|induction of positive chemotaxis|regulation of calcium ion transport|cell chemotaxis|chemokine-mediated signaling pathway|positive regulation of monocyte chemotaxis|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of leukocyte apoptotic process|positive regulation of T cell migration|,cytokine activity|chemokine activity|growth factor activity|chemokine receptor binding|CXCR chemokine receptor binding|,10,-0.6,0.554,10,-0.1,0.0255,0,0,0,0.898,0,0,-1.7,1.6
ENSMUSG00000022315,SLC30A8,"solute carrier family 30 (zinc transporter), member 8",cell|plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|secretory granule|cytoplasmic vesicle|,transport|ion transport|cation transport|zinc ion transport|cellular zinc ion homeostasis|cellular zinc ion homeostasis|response to glucose|response to glucose|insulin secretion|insulin secretion|positive regulation of insulin secretion|sequestering of zinc ion|transmembrane transport|regulation of vesicle-mediated transport|regulation of sequestering of zinc ion|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|cation transmembrane transporter activity|protein homodimerization activity|,10,0.3,1.13,10,0,0,0,0,0,0.898,0,0,-1.2,1.7
ENSMUSG00000022893,ADAMTS1,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1",extracellular region|proteinaceous extracellular matrix|basement membrane|cytoplasm|extracellular matrix|cytoplasmic vesicle|,ovulation from ovarian follicle|kidney development|proteolysis|negative regulation of angiogenesis|heart trabecula formation|,metalloendopeptidase activity|metalloendopeptidase activity|metalloendopeptidase activity|protein binding|heparin binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.1,0.116,0,0,0,0.898,0,0,-1.4,1.6
ENSMUSG00000050936,HIST2H2BB,"histone cluster 2, H2bb",nucleus|extracellular vesicular exosome|,None,None,10,0.5,1.8,10,-0.1,0.273,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000091215,GM17252,"predicted gene, 17252",None,None,None,10,0.1,0.245,10,0,0,0,0,0,0.898,0,0,-1.4,1.7
ENSMUSG00000053490,TRIM60,tripartite motif-containing 60,intracellular|,biological_process|,protein binding|zinc ion binding|metal ion binding|,10,-0.1,0.492,10,0.7,0.737,0,0,0,0.898,0,0,-0.8,2
ENSMUSG00000042459,BPIFA2,"BPI fold containing family A, member 2",extracellular region|extracellular region|secretory granule|extracellular vesicular exosome|,biological_process|,lipopolysaccharide binding|lipid binding|,10,0.1,0.174,10,0,0,0,0,0,0.898,0,0,-1.7,1.3
ENSMUSG00000029413,NAAA,N-acylethanolamine acid amidase,cytoplasm|lysosome|extracellular vesicular exosome|,lipid metabolic process|,"histone deacetylase activity|transcription factor binding|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|",10,0.1,0.143,10,-0.1,0.198,0,0,0,0.898,0,0,-1.6,1.3
ENSMUSG00000025423,PIAS2,protein inhibitor of activated STAT 2,nucleus|nucleus|nuclear body|PML body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|protein sumoylation|protein sumoylation|androgen receptor signaling pathway|regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of dendrite morphogenesis|regulation of androgen receptor signaling pathway|negative regulation of androgen receptor signaling pathway|","nucleic acid binding|DNA binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|SUMO ligase activity|protein domain specific binding|estrogen receptor binding|ubiquitin protein ligase binding|glucocorticoid receptor binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|androgen receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.1,0.0667,0,0,0,0.898,0,0,-1.9,1
ENSMUSG00000027408,CPXM1,carboxypeptidase X 1 (M14 family),extracellular region|extracellular space|,cell adhesion|,metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.3,1.26,10,0.1,0.0214,0,0,0,0.898,0,0,-1.8,1
ENSMUSG00000023013,AQP2,aquaporin 2,cytoplasm|lysosome|early endosome|rough endoplasmic reticulum|Golgi apparatus|trans-Golgi network|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|transport vesicle|clathrin-coated vesicle|integral component of endosome membrane|cytoplasmic vesicle|protein complex|pore complex|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|exocytic vesicle|,renal water transport|transport|ion transport|water transport|water transport|cell volume homeostasis|apoptotic process|glycerol transport|actin filament depolymerization|carbohydrate transmembrane transport|cellular response to water deprivation|cellular response to water deprivation|positive regulation of calcium ion transport|transmembrane transport|cellular response to copper ion|cellular response to mercury ion|,actin binding|transporter activity|water transmembrane transporter activity|glycerol transmembrane transporter activity|water channel activity|water channel activity|porin activity|PDZ domain binding|,10,0,0,10,1.1,0.492,0,0,0,0.898,0,0,-0.6,2
ENSMUSG00000028793,RNF19B,ring finger protein 19B,cell|cytoplasm|membrane|integral component of membrane|cytolytic granule|,immune system process|natural killer cell mediated cytotoxicity|interferon-gamma secretion|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000019194,SCN1B,"sodium channel, voltage-gated, type I, beta",voltage-gated sodium channel complex|intercalated disc|membrane|integral component of membrane|T-tubule|node of Ranvier|sodium channel complex|,regulation of sodium ion transport|transport|ion transport|sodium ion transport|axon guidance|positive regulation of sodium ion transport|positive regulation of neuron projection development|neuronal action potential propagation|corticospinal neuron axon guidance|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|locomotion|response to pyrethroid|membrane depolarization|cardiac muscle contraction|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of atrial cardiac muscle cell membrane depolarization|cardiac conduction|cardiac muscle cell action potential involved in contraction|membrane depolarization during cardiac muscle cell action potential|membrane depolarization during Purkinje myocyte cell action potential|regulation of heart rate by cardiac conduction|regulation of sodium ion transmembrane transporter activity|,voltage-gated ion channel activity|voltage-gated sodium channel activity|sodium channel activity|protein binding|sodium channel regulator activity|sodium channel inhibitor activity|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|voltage-gated sodium channel activity involved in cardiac muscle cell action potential|voltage-gated sodium channel activity involved in Purkinje myocyte action potential|,10,0.4,0.437,10,0,0,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000022822,ABCC5,"ATP-binding cassette, sub-family C (CFTR/MRP), member 5",membrane|integral component of membrane|perinuclear region of cytoplasm|,transport|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,-0.3,0.461,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000006611,HFE,hemochromatosis,early endosome|membrane|integral component of membrane|cytoplasmic vesicle|MHC class I protein complex|apical part of cell|basal part of cell|perinuclear region of cytoplasm|recycling endosome|,positive regulation of T cell mediated cytotoxicity|immune system process|antigen processing and presentation of peptide antigen via MHC class I|immune response|antigen processing and presentation|hormone biosynthetic process|iron ion homeostasis|multicellular organismal iron ion homeostasis|iron ion import into cell|iron ion import into cell|,receptor binding|peptide antigen binding|,10,-0.5,0.39,10,0.1,0.0234,0,0,0,0.898,0,0,-2,1.1
ENSMUSG00000000058,CAV2,caveolin 2,acrosomal membrane|intracellular|nucleus|nuclear inner membrane|cytoplasm|endoplasmic reticulum|Golgi apparatus|lipid particle|cytosol|plasma membrane|plasma membrane|integral component of plasma membrane|caveola|caveola|cell surface|membrane|membrane|transport vesicle|extrinsic component of cytoplasmic side of plasma membrane|extrinsic component of cytoplasmic side of plasma membrane|cytoplasmic vesicle|protein complex|membrane raft|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,negative regulation of endothelial cell proliferation|negative regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|endocytosis|vesicle fusion|vesicle fusion|mitochondrion organization|endoplasmic reticulum organization|synaptic transmission|negative regulation of cell proliferation|vesicle organization|negative regulation of transforming growth factor beta receptor signaling pathway|vesicle docking|vesicle docking|skeletal muscle fiber development|protein oligomerization|positive regulation of dopamine receptor signaling pathway|positive regulation of dopamine receptor signaling pathway|caveola assembly|caveola assembly|,SNARE binding|syntaxin binding|D1 dopamine receptor binding|D1 dopamine receptor binding|protein homodimerization activity|phosphoprotein binding|,10,0.1,0.193,10,-0.2,0.523,0,0,0,0.898,0,0,-1.4,1.5
ENSMUSG00000078179,RNF148,ring finger protein 148,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.1,0.26,10,0.1,0.226,0,0,0,0.898,0,0,-0.9,2
ENSMUSG00000042258,ISL1,"ISL1 transcription factor, LIM/homeodomain",intracellular|nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|neural crest cell migration|heart morphogenesis|secondary heart field specification|outflow tract septum morphogenesis|outflow tract morphogenesis|endocardial cushion morphogenesis|cardiac right ventricle morphogenesis|regulation of secondary heart field cardioblast proliferation|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|heart development|positive regulation of cell proliferation|regulation of gene expression|positive regulation vascular endothelial growth factor production|spinal cord motor neuron cell fate specification|spinal cord motor neuron differentiation|visceral motor neuron differentiation|trigeminal nerve development|pituitary gland development|neuron differentiation|neuron differentiation|pancreas development|retinal ganglion cell axon guidance|positive regulation of insulin secretion|positive regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of interferon-gamma production|positive regulation of interleukin-1 alpha production|positive regulation of interleukin-1 beta production|positive regulation of interleukin-12 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|negative regulation of intracellular estrogen receptor signaling pathway|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of DNA binding|negative regulation of neuron apoptotic process|negative regulation of neuron differentiation|positive regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|neuron fate commitment|neuron fate specification|mesenchymal cell differentiation|sensory system development|peripheral nervous system neuron development|peripheral nervous system neuron axonogenesis|negative regulation of inflammatory response|ventricular cardiac muscle tissue morphogenesis|pharyngeal system development|cardiac muscle cell myoblast differentiation|innervation|atrial septum morphogenesis|cardiac cell fate determination|cardiac cell fate determination|positive regulation of granulocyte colony-stimulating factor production|negative regulation of protein homodimerization activity|negative regulation of canonical Wnt signaling pathway|positive regulation of macrophage colony-stimulating factor production|",RNA polymerase II activating transcription factor binding|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription coactivator activity|enhancer sequence-specific DNA binding|DNA binding|chromatin binding|protein binding|zinc ion binding|ligand-dependent nuclear receptor binding|estrogen receptor binding|bHLH transcription factor binding|sequence-specific DNA binding|metal ion binding|,10,0.3,1.05,10,1.1,0.606,0,0,0,0.898,0,0,-0.5,2
ENSMUSG00000027849,SYT6,synaptotagmin VI,cell|cytoplasm|cytosol|plasma membrane|synaptic vesicle|membrane|integral component of membrane|extrinsic component of membrane|cell junction|cytoplasmic vesicle|synapse|perinuclear endoplasmic reticulum|,transport|acrosome reaction|acrosomal vesicle exocytosis|,transporter activity|protein binding|syntaxin binding|clathrin binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|calcium-dependent protein binding|,10,-0.1,0.152,10,0,0,0,0,0,0.898,0,0,-2,1
ENSMUSG00000018411,MAPT,microtubule-associated protein tau,intracellular|cell|nucleus|cytoplasm|cytoskeleton|microtubule|plasma membrane|axoneme|microtubule cytoskeleton|membrane|axon|axon|growth cone|nuclear periphery|cytoplasmic ribonucleoprotein granule|cell projection|neuron projection|axonal growth cone|tubulin complex|,microtubule cytoskeleton organization|microtubule cytoskeleton organization|neuron migration|apoptotic process|axonogenesis|response to nutrient|adult walking behavior|axon cargo transport|intrinsic apoptotic signaling pathway in response to oxidative stress|response to organic substance|regulation of autophagy|positive regulation of microtubule polymerization|negative regulation of intracellular transport|positive regulation of axon extension|positive regulation of axon extension|mitochondrion transport along microtubule|axon extension|regulation of microtubule-based movement|,protein binding|microtubule binding|microtubule binding|tubulin binding|SH3 domain binding|enzyme binding|protein kinase binding|protein kinase binding|protein domain specific binding|apolipoprotein binding|lipoprotein particle binding|,10,0.1,0.15,10,-0.1,0.116,0,0,0,0.898,0,0,-1,1.9
ENSMUSG00000089832,SHKBP1,Sh3kbp1 binding protein 1,cellular_component|,biological_process|protein homooligomerization|,protein binding|,10,-0.1,0.394,10,0,0,0,0,0,0.898,0,0,-1.5,1.4
ENSMUSG00000036091,HYAL3,hyaluronoglucosaminidase 3,extracellular region|lysosome|cytoplasmic vesicle|,carbohydrate metabolic process|inflammatory response|metabolic process|response to virus|response to virus|hyaluronan catabolic process|cellular response to interleukin-1|cellular response to UV-B|,"catalytic activity|hyalurononglucosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hyaluronoglucuronidase activity|",10,0.1,0.0409,10,0,0,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000029909,PRSS37,"protease, serine 37",extracellular region|nucleus|,proteolysis|binding of sperm to zona pellucida|cell migration|protein maturation|,molecular_function|catalytic activity|serine-type endopeptidase activity|metal ion binding|,10,-0.2,0.557,10,0,0,0,0,0,0.898,0,0,-1.6,1.4
ENSMUSG00000019769,SYNE1,"spectrin repeat containing, nuclear envelope 1",cell|nucleus|nuclear envelope|nuclear envelope|nuclear envelope|cytoplasm|Golgi apparatus|spindle|cytoskeleton|membrane|integral component of membrane|sarcomere|midbody|nuclear membrane|SUN-KASH complex|dendritic spine|postsynaptic membrane|perinuclear region of cytoplasm|,Golgi organization|establishment of nucleus localization|muscle cell differentiation|positive regulation of receptor-mediated endocytosis|regulation of dendrite morphogenesis|cytoskeletal anchoring at nuclear membrane|nuclear matrix anchoring at nuclear membrane|,actin binding|receptor binding|protein binding|lamin binding|enzyme binding|protein homodimerization activity|poly(A) RNA binding|actin filament binding|,10,0.1,0.0223,10,-0.1,0.0395,0,0,0,0.898,0,0,-1.3,1.7
ENSMUSG00000058498,RNF207,ring finger protein 207,cellular_component|intracellular|,biological_process|,zinc ion binding|metal ion binding|,10,0.1,0.0245,10,0,0,0,0,0,0.898,0,0,-1.5,1.6
ENSMUSG00000009030,PDCL,phosducin-like,cytoplasm|,protein folding|visual perception|response to stimulus|negative regulation of protein refolding|heterotrimeric G-protein complex assembly|,protein complex binding|,10,3.7,159,10,3.1,243,3.3,401,401,1.00E-05,1,1,2.8,4.2
ENSMUSG00000029467,ATP2A2,"ATPase, Ca++ transporting, cardiac muscle, slow twitch 2",endoplasmic reticulum|endoplasmic reticulum membrane|vesicle membrane|membrane|membrane|integral component of membrane|sarcoplasmic reticulum|sarcoplasmic reticulum|sarcoplasmic reticulum|extrinsic component of cytoplasmic side of plasma membrane|protein complex|perinuclear region of cytoplasm|,regulation of the force of heart contraction|ATP catabolic process|ATP catabolic process|transport|ion transport|cation transport|calcium ion transport|cellular calcium ion homeostasis|cellular calcium ion homeostasis|cellular calcium ion homeostasis|regulation of muscle contraction|ER-nucleus signaling pathway|response to peptide hormone|negative regulation of heart contraction|sarcoplasmic reticulum calcium ion transport|calcium ion transmembrane transport|calcium ion transmembrane transport|,nucleotide binding|calcium-transporting ATPase activity|calcium-transporting ATPase activity|calcium ion binding|protein binding|ATP binding|protein C-terminus binding|protein C-terminus binding|hydrolase activity|cation-transporting ATPase activity|enzyme binding|enzyme binding|lutropin-choriogonadotropic hormone receptor binding|S100 protein binding|metal ion binding|,10,1.9,132,10,1.7,171,1.8,302,302,1.00E-05,1,1,1.5,2.3
ENSMUSG00000038503,MESDC2,mesoderm development candidate 2,endoplasmic reticulum|plasma membrane|,protein folding|protein folding|mesoderm development|Wnt signaling pathway|protein localization to cell surface|,protein binding|low-density lipoprotein particle receptor binding|,10,3,136,10,2.4,165,2.7,298,298,1.00E-05,1,1,2.3,3.4
ENSMUSG00000008036,AP2S1,"adaptor-related protein complex 2, sigma 1 subunit",plasma membrane|coated pit|membrane|membrane coat|AP-2 adaptor complex|,transport|intracellular protein transport|endocytosis|protein transport|vesicle-mediated transport|,molecular_function|protein transporter activity|,10,2.1,142,10,1.9,121,2.1,262,262,1.00E-05,1,1,1.7,2.5
ENSMUSG00000004677,MYO9B,myosin IXb,ruffle|ruffle|intracellular|cytoplasm|cytoskeleton|actin filament|cell cortex|membrane|myosin complex|lamellipodium|lamellipodium|filamentous actin|filopodium tip|perinuclear region of cytoplasm|,monocyte chemotaxis|ATP catabolic process|signal transduction|Rho protein signal transduction|Rho protein signal transduction|establishment of cell polarity|positive regulation of Rho GTPase activity|positive regulation of Rho GTPase activity|positive regulation of Rho GTPase activity|actin-myosin filament sliding|intracellular signal transduction|positive regulation of GTPase activity|macrophage chemotaxis|lamellipodium morphogenesis|,microfilament motor activity|microfilament motor activity|nucleotide binding|motor activity|actin binding|GTPase activator activity|Rho GTPase activator activity|Rho GTPase activator activity|Rho GTPase activator activity|calmodulin binding|ATP binding|zinc ion binding|ATPase activity|actin-dependent ATPase activity|ATP-dependent protein binding|ADP binding|metal ion binding|actin filament binding|,10,1.8,103,10,2.2,152,1.9,254,254,1.00E-05,1,1,1.6,2.5
ENSMUSG00000021901,BAP1,Brca1 associated protein 1,intracellular|nucleus|nucleus|cytoplasm|PR-DUB complex|,regulation of cell growth|proteolysis|ubiquitin-dependent protein catabolic process|negative regulation of cell proliferation|chromatin modification|protein deubiquitination|protein deubiquitination|monoubiquitinated protein deubiquitination|monoubiquitinated histone H2A deubiquitination|regulation of cell cycle|protein K48-linked deubiquitination|,chromatin binding|ubiquitin thiolesterase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,1.5,66.9,10,1.7,120,1.6,186,186,1.00E-05,1,1,1.3,2
ENSMUSG00000030036,MOGS,mannosyl-oligosaccharide glucosidase,endoplasmic reticulum|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,metabolic process|oligosaccharide metabolic process|,"molecular_function|catalytic activity|mannosyl-oligosaccharide glucosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,2,98.6,10,2.2,62.5,2.1,160,160,1.00E-05,1,1,1.7,2.7
ENSMUSG00000007670,KHSRP,KH-type splicing regulatory protein,nucleus|cytoplasm|cytoplasmic stress granule|membrane|dendrite|neuronal cell body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|mRNA catabolic process|transport|RNA splicing|mRNA transport|regulation of miRNA metabolic process|",DNA binding|RNA binding|mRNA binding|mRNA 3'-UTR binding|poly(A) RNA binding|,10,1.2,42.2,10,1.5,99.1,1.4,140,140,1.00E-05,1,1,1.1,1.8
ENSMUSG00000020738,SUMO2,SMT3 suppressor of mif two 3 homolog 2 (yeast),nucleus|PML body|,"protein sumoylation|protein sumoylation|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular protein localization|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",SUMO ligase activity|ubiquitin protein ligase binding|poly(A) RNA binding|,10,1.5,57.9,9,1.7,43.5,1.6,101,101,1.00E-05,1,1,1.1,2.2
ENSMUSG00000024271,ELP2,elongator acetyltransferase complex subunit 2,nucleus|cytoplasm|transcription elongation factor complex|Elongator holoenzyme complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of JAK-STAT cascade|",DNA binding|protein binding|protein kinase binding|,9,0.9,19.6,9,1.7,80.8,1.4,97.3,97.3,1.00E-05,1,1,1.1,2.1
ENSMUSG00000027108,OLA1,Obg-like ATPase 1,nucleus|cytoplasm|membrane|extracellular vesicular exosome|,ATP catabolic process|,nucleotide binding|ATP binding|GTP binding|hydrolase activity|metal ion binding|,10,1.5,40.3,10,1.3,48.8,1.5,88.6,88.6,1.00E-05,1,1,1.1,2.2
ENSMUSG00000028293,SLC35A1,"solute carrier family 35 (CMP-sialic acid transporter), member 1",Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,transport|carbohydrate transport|nucleotide-sugar transport|,nucleotide-sugar transmembrane transporter activity|sugar:proton symporter activity|,10,1.6,31.1,10,1.6,57.7,1.6,88.4,88.4,1.00E-05,1,1,1.1,2.2
ENSMUSG00000001289,PFDN5,prefoldin 5,nucleus|prefoldin complex|,"protein folding|negative regulation of transcription, DNA-templated|retina development in camera-type eye|negative regulation of canonical Wnt signaling pathway|",unfolded protein binding|,10,1.4,30.9,10,1.4,51.6,1.4,82.1,82.1,1.00E-05,1,1,1,1.9
ENSMUSG00000030107,USP18,ubiquitin specific peptidase 18,nucleus|,proteolysis|ubiquitin-dependent protein catabolic process|ISG15-protein conjugation|,protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|ISG15-specific protease activity|ubiquitinyl hydrolase activity|,10,-1.7,45.7,9,-1.8,35.4,-1.7,80.6,-80.6,1.00E-05,1,1,-2.2,-1.4
ENSMUSG00000028062,LAMTOR2,"late endosomal/lysosomal adaptor, MAPK and MTOR activator 2",lysosome|lysosomal membrane|endosome|late endosome|membrane|extracellular vesicular exosome|Ragulator complex|,activation of MAPKK activity|cell growth|positive regulation of TOR signaling|cellular protein localization|positive regulation of GTPase activity|cellular response to amino acid stimulus|,guanyl-nucleotide exchange factor activity|protein binding|protein complex scaffold|,10,0.8,18.1,9,2.4,67,1.5,77.8,77.8,2.00E-05,1,1,1.3,2.7
ENSMUSG00000003033,AP1M1,"adaptor-related protein complex AP-1, mu subunit 1",intracellular|cell|Golgi apparatus|trans-Golgi network|membrane|membrane|clathrin adaptor complex|cytoplasmic vesicle|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|melanosome organization|endosome to melanosome transport|,protein binding|,10,1.4,53.6,10,1,23.7,1.1,75.3,75.3,5.00E-05,1,1,0.9,1.6
ENSMUSG00000046985,TAPT1,transmembrane anterior posterior transformation 1,cellular_component|membrane|integral component of membrane|,in utero embryonic development|multicellular organismal development|post-embryonic development|embryonic skeletal system development|,molecular_function|,10,1.4,31.8,10,2.3,43.1,1.5,73,73,6.00E-05,1,1,1.2,2.4
ENSMUSG00000025613,CCT8,"chaperonin containing Tcp1, subunit 8 (theta)",zona pellucida receptor complex|cytoplasm|centrosome|cytosol|chaperonin-containing T-complex|cytoskeleton|microtubule|aggresome|cell body|intermediate filament cytoskeleton|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|,nucleotide binding|protein binding|ATP binding|unfolded protein binding|,9,1.9,36,8,1.6,37.5,1.6,73,73,6.00E-05,1,1,1,2.6
ENSMUSG00000007739,CCT4,"chaperonin containing Tcp1, subunit 4 (delta)",zona pellucida receptor complex|nucleus|cytoplasm|centrosome|chaperonin-containing T-complex|cytoskeleton|microtubule|cell body|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|,nucleotide binding|protein binding|ATP binding|poly(A) RNA binding|unfolded protein binding|,8,1.4,29.4,9,1.4,43.5,1.4,72.5,72.5,6.00E-05,1,1,1.1,2
ENSMUSG00000029518,RAB35,"RAB35, member RAS oncogene family",mitochondrion|endosome|plasma membrane|coated pit|endosome membrane|membrane|cell projection membrane|cytoplasmic vesicle|intercellular bridge|clathrin-coated endocytic vesicle|extracellular vesicular exosome|,cytokinesis|transport|small GTPase mediated signal transduction|protein localization|protein transport|endosomal transport|antigen processing and presentation|neuron projection development|protein localization to endosome|cellular response to nerve growth factor stimulus|,"nucleotide binding|protein binding|GTP binding|phosphatidylinositol-4,5-bisphosphate binding|GDP binding|",10,1.2,23.7,10,2.1,47,1.3,68.9,68.9,8.00E-05,1,1,1,2.2
ENSMUSG00000034216,VPS18,vacuolar protein sorting 18 (yeast),lysosome|lysosomal membrane|endosome|early endosome|actin filament|membrane|HOPS complex|,transport|intracellular protein transport|endosome organization|endosome organization|lysosome organization|protein transport|vesicle-mediated transport|viral entry into host cell|,actin binding|protein binding|metal ion binding|,10,1.7,46,9,1,22.7,1.3,64.7,64.7,0.00012,1,1,1,2.2
ENSMUSG00000034024,CCT2,"chaperonin containing Tcp1, subunit 2 (beta)",zona pellucida receptor complex|cytoplasm|chaperonin-containing T-complex|microtubule|cell body|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|chaperone-mediated protein complex assembly|,nucleotide binding|molecular_function|ATP binding|unfolded protein binding|,7,2.1,27.6,7,2.2,36.5,2.1,63.5,63.5,0.00016,1,1,1.5,3.5
ENSMUSG00000009907,VPS4B,vacuolar protein sorting 4b (yeast),nucleus|cytoplasm|lysosome|endosome|early endosome|late endosome|vacuolar membrane|cytosol|cytosol|endosome membrane|membrane|extracellular vesicular exosome|,ATP catabolic process|transport|potassium ion transport|endosome organization|cell cycle|protein transport|endosomal transport|cholesterol transport|intracellular cholesterol transport|endosome to lysosome transport via multivesicular body sorting pathway|response to lipid|regulation of viral process|cell division|positive regulation of viral release from host cell|,nucleotide binding|protein binding|ATP binding|protein C-terminus binding|hydrolase activity|ATPase activity|,9,-1.3,24.7,8,-1.6,32.3,-1.5,56.1,-56.1,0.00031,1,1,-2,-1
ENSMUSG00000021905,DPH3,diphthamine biosynthesis 3,nucleus|cytoplasm|,negative regulation of protein secretion|positive regulation of binding|,metal ion binding|,9,1.3,13.2,9,1.6,37.5,1.3,49.9,49.9,0.00083,0,1,0.8,2.1
ENSMUSG00000041236,VPS41,vacuolar protein sorting 41 (yeast),lysosomal membrane|early endosome|late endosome|Golgi-associated vesicle|cytosol|microtubule cytoskeleton|membrane|HOPS complex|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|Golgi vesicle transport|,protein binding|microtubule binding|zinc ion binding|metal ion binding|,10,0.8,10.1,9,1.7,40.8,1.3,47,47,0.0016,0,1,0.7,2.1
ENSMUSG00000021669,COL4A3BP,"collagen, type IV, alpha 3 (Goodpasture antigen) binding protein",nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|Golgi apparatus|cytosol|perinuclear region of cytoplasm|,cell morphogenesis|in utero embryonic development|heart morphogenesis|ceramide metabolic process|transport|lipid transport|muscle contraction|endoplasmic reticulum organization|signal transduction|cell proliferation|phosphorylation|response to endoplasmic reticulum stress|ER to Golgi ceramide transport|lipid homeostasis|mitochondrion morphogenesis|,lipid binding|kinase activity|ceramide transporter activity|phosphatidylinositol-4-phosphate binding|ceramide binding|,10,1.3,26.3,9,1.4,20.9,1.3,46.8,46.8,0.00168,0,1,0.9,1.9
ENSMUSG00000042709,ATPAF2,ATP synthase mitochondrial F1 complex assembly factor 2,mitochondrion|nuclear speck|,biological_process|proton-transporting ATP synthase complex assembly|,molecular_function|,10,1.4,11.8,10,1.1,34.2,1.3,45.3,45.3,0.00213,0,0,0.9,1.9
ENSMUSG00000049624,SLC17A5,"solute carrier family 17 (anion/sugar transporter), member 5",cytoplasm|lysosome|lysosomal membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cell junction|cytoplasmic vesicle|synapse|,transport|amino acid transport|sialic acid transport|ion transmembrane transport|transmembrane transport|,sialic acid transmembrane transporter activity|symporter activity|,10,0.8,12.5,10,1.1,33.3,1,44.7,44.7,0.00224,0,0,0.7,1.6
ENSMUSG00000029434,VPS33A,vacuolar protein sorting 33A (yeast),lysosome|lysosomal membrane|endosome|early endosome|late endosome|membrane|HOPS complex|cytoplasmic vesicle|perinuclear region of cytoplasm|,transport|vesicle docking involved in exocytosis|protein transport|vesicle-mediated transport|platelet formation|melanosome localization|lysosome localization|pigmentation|regulation of developmental pigmentation|,protein complex binding|,10,0.5,6.66,10,1.5,39.9,1.1,43.4,43.4,0.00255,0,0,0.6,1.9
ENSMUSG00000027166,DNAJC24,"DnaJ (Hsp40) homolog, subfamily C, member 24",cytoplasm|cytoskeleton|,transport|positive regulation of ATPase activity|oxidation-reduction process|,ATPase activator activity|ferrous iron binding|zinc ion binding|metal ion binding|,10,1.2,24.6,10,1,17.9,1.1,42,42,0.00283,0,0,0.7,1.5
ENSMUSG00000039662,ICMT,isoprenylcysteine carboxyl methyltransferase,endoplasmic reticulum|membrane|integral component of membrane|,in utero embryonic development|liver development|protein methylation|C-terminal protein methylation|C-terminal protein methylation|protein localization|positive regulation of cell proliferation|methylation|multicellular organism growth|S-adenosylhomocysteine metabolic process|S-adenosylmethioninamine metabolic process|regulation of Ras protein signal transduction|regulation of RNA biosynthetic process|,protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity|protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity|cAMP response element binding protein binding|methyltransferase activity|transferase activity|,10,0.9,19.3,10,0.9,23,0.9,41.9,41.9,0.00285,0,0,0.7,1.5
ENSMUSG00000030533,UNC45A,unc-45 homolog A (C. elegans),nucleus|cytoplasm|Golgi apparatus|,multicellular organismal development|muscle organ development|cell differentiation|chaperone-mediated protein folding|,protein binding|Hsp90 protein binding|,10,2,36.3,10,1,6.99,1.6,40.3,40.3,0.00305,0,0,0.9,2.8
ENSMUSG00000032557,UBA5,ubiquitin-like modifier activating enzyme 5,nucleus|cytoplasm|cytosol|intracellular membrane-bounded organelle|,response to endoplasmic reticulum stress|oxidation-reduction process|protein ufmylation|protein ufmylation|,nucleotide binding|catalytic activity|ATP binding|metal ion binding|NAD binding|UFM1 activating enzyme activity|UFM1 activating enzyme activity|,9,0.5,4.63,9,1.6,39.5,1.4,39,39,0.00344,0,0,0.6,2.5
ENSMUSG00000010936,VAC14,Vac14 homolog (S. cerevisiae),endosome|vacuolar membrane|endoplasmic reticulum|endosome membrane|membrane|intracellular membrane-bounded organelle|PAS complex|,response to osmotic stress|cell death|positive regulation of phosphorylation|positive regulation of catalytic activity|regulation of lipid kinase activity|,kinase activator activity|,10,-1,29.8,10,-1.7,11.1,-1,38.9,-38.9,0.00346,0,0,-1.7,-0.7
ENSMUSG00000023118,SYMPK,symplekin,nucleus|nucleoplasm|cytoplasm|cytoskeleton|plasma membrane|tight junction|membrane|cell junction|,mRNA polyadenylation|mRNA processing|cell adhesion|positive regulation of protein dephosphorylation|,molecular_function|,10,1.7,38.6,10,-1.4,1.39,1.4,37.6,37.6,0.00369,0,0,0.9,2.5
ENSMUSG00000030850,ATE1,arginyltransferase 1,nucleus|nucleus|cytoplasm|cytoplasm|,protein arginylation|,"arginyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.9,15.8,10,1,22,0.9,37.4,37.4,0.00377,0,0,0.6,1.3
ENSMUSG00000071644,EEF1G,eukaryotic translation elongation factor 1 gamma,nucleus|membrane|extracellular vesicular exosome|,translation|translational elongation|,translation elongation factor activity|,8,0.6,6.23,7,1.4,33.2,1.1,37,37,0.00391,0,0,0.6,2.1
ENSMUSG00000073792,ALG6,"asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,protein N-linked glycosylation|,"transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|glucosyltransferase activity|",9,1.8,32.3,9,0.6,7.87,1.3,36.3,36.3,0.00409,0,0,0.5,2.2
ENSMUSG00000038417,FIG4,FIG4 homolog (S. cerevisiae),endosome|endoplasmic reticulum|Golgi apparatus|endosome membrane|membrane|recycling endosome|,vacuole organization|locomotory behavior|cell death|positive regulation of neuron projection development|dephosphorylation|negative regulation of myelination|negative regulation of myelination|myelin assembly|pigmentation|phosphatidylinositol metabolic process|neuron development|neuron development|,"phosphatidylinositol-3-phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|phosphatidylinositol bisphosphate phosphatase activity|phosphoric ester hydrolase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,-0.8,20.9,10,-0.8,14,-0.8,34.5,-34.5,0.00457,0,0,-1.2,-0.5
ENSMUSG00000040423,RC3H1,RING CCCH (C3H) domains 1,cytoplasmic mRNA processing body|cytoplasm|cytoplasmic stress granule|,nuclear-transcribed mRNA catabolic process|B cell homeostasis|regulation of germinal center formation|negative regulation of germinal center formation|regulation of gene expression|posttranscriptional regulation of gene expression|posttranscriptional regulation of gene expression|negative regulation of B cell proliferation|cytoplasmic mRNA processing body assembly|T cell proliferation|T cell homeostasis|regulation of mRNA stability|negative regulation of T-helper cell differentiation|negative regulation of activated T cell proliferation|lymph node development|spleen development|regulation of T cell receptor signaling pathway|T follicular helper cell differentiation|positive regulation of NIK/NF-kappaB signaling|,RNA binding|mRNA binding|mRNA 3'-UTR binding|protein binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,1,22.7,10,0.7,12.3,0.9,34.2,34.2,0.0047,0,0,0.6,1.3
ENSMUSG00000029047,PEX10,peroxisomal biogenesis factor 10,intracellular|peroxisome|peroxisomal membrane|integral component of peroxisomal membrane|membrane|,peroxisome organization|protein import into peroxisome matrix|,protein C-terminus binding|zinc ion binding|metal ion binding|,10,1,20.1,10,0.8,14.3,1,33.6,33.6,0.00496,0,0,0.6,1.6
ENSMUSG00000043940,WDFY3,WD repeat and FYVE domain containing 3,nuclear envelope|nuclear envelope|cytoplasm|cytoplasm|cytoplasm|autophagic vacuole|autophagic vacuole|membrane|inclusion body|PML body|extrinsic component of membrane|Atg12-Atg5-Atg16 complex|,positive regulation of macroautophagy|aggrephagy|,"beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity|1-phosphatidylinositol binding|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,1.1,7,10,1.9,28.7,1.2,33.6,33.6,0.00496,0,0,0.8,2.7
ENSMUSG00000045103,DMD,"dystrophin, muscular dystrophy",intracellular|nucleus|cytoplasm|cytoskeleton|plasma membrane|cell surface|dystrophin-associated glycoprotein complex|dystrophin-associated glycoprotein complex|membrane|Z disc|cell junction|cell-substrate junction|filopodium|filopodium membrane|sarcolemma|sarcolemma|costamere|protein complex|neuron projection terminus|membrane raft|synapse|postsynaptic membrane|,"positive regulation of cell-matrix adhesion|regulation of heart rate|regulation of heart rate|regulation of transcription, DNA-templated|muscle organ development|skeletal muscle tissue development|skeletal muscle tissue development|establishment of blood-nerve barrier|regulation of gene expression|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|positive regulation of neuron projection development|regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion|regulation of skeletal muscle contraction|myotube cell development|olfactory nerve structural organization|negative regulation of peptidyl-serine phosphorylation|cellular protein localization|cellular protein localization|peptide biosynthetic process|cellular protein complex assembly|neurotransmitter receptor metabolic process|positive regulation of neuron differentiation|muscle cell cellular homeostasis|muscle fiber development|nucleus localization|cardiac muscle contraction|regulation of ryanodine-sensitive calcium-release channel activity|establishment of glial blood-brain barrier|cardiac muscle cell action potential|regulation of cellular response to growth factor stimulus|regulation of voltage-gated calcium channel activity|negative regulation of peptidyl-cysteine S-nitrosylation|positive regulation of sodium ion transmembrane transporter activity|",dystroglycan binding|actin binding|calcium ion binding|protein binding|zinc ion binding|structural constituent of muscle|myosin binding|vinculin binding|metal ion binding|nitric-oxide synthase binding|,10,0.5,4.97,10,1.6,31.5,0.9,32.8,32.8,0.00533,0,0,0.5,2.2
ENSMUSG00000022031,ELP3,elongator acetyltransferase complex subunit 3,"nucleus|nucleolus|cytoplasm|transcription elongation factor complex|DNA-directed RNA polymerase II, holoenzyme|Elongator holoenzyme complex|","transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription elongation from RNA polymerase II promoter|positive regulation of cell migration|regulation of protein kinase activity|","DNA binding|catalytic activity|histone acetyltransferase activity|N-acetyltransferase activity|phosphorylase kinase regulator activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|iron-sulfur cluster binding|",9,1.2,13.7,9,0.9,20.3,1,32.7,32.7,0.00536,0,0,0.7,1.5
ENSMUSG00000040028,ELAVL1,"ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)",nucleus|nucleus|cytoplasm|membrane|,regulation of translation|positive regulation of translation|positive regulation of translation|positive regulation of translation|mRNA stabilization|mRNA stabilization|3'-UTR-mediated mRNA stabilization|regulation of stem cell maintenance|,nucleotide binding|nucleic acid binding|RNA binding|double-stranded RNA binding|mRNA 3'-UTR binding|mRNA 3'-UTR binding|protein binding|AU-rich element binding|protein kinase binding|mRNA 3'-UTR AU-rich region binding|poly(A) RNA binding|,10,1.2,25.7,9,0.6,10,0.9,32.7,32.7,0.00536,0,0,0.6,1.4
ENSMUSG00000094248,HIST1H2AO,"histone cluster 1, H2ao",nucleus|,biological_process|,molecular_function|,3,-1.4,34.3,3,0.5,3.79,-1.4,32.5,-32.5,0.0055,0,0,-2,-1.2
ENSMUSG00000006732,METTL1,methyltransferase like 1,nucleus|cytoplasm|,tRNA modification|tRNA processing|tRNA methylation|methylation|RNA (guanine-N7)-methylation|,tRNA binding|RNA binding|methyltransferase activity|tRNA (guanine-N7-)-methyltransferase activity|tRNA (guanine-N7-)-methyltransferase activity|transferase activity|,8,0.8,4.85,8,1.6,28.6,0.9,31,31,0.00647,0,0,0.6,2.4
ENSMUSG00000029447,CCT6A,"chaperonin containing Tcp1, subunit 6a (zeta)",acrosomal vesicle|zona pellucida receptor complex|cytoplasm|chaperonin-containing T-complex|microtubule|cell body|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|,nucleotide binding|protein binding|ATP binding|poly(A) RNA binding|unfolded protein binding|,7,0.7,5.82,6,1.3,27.1,1,30.6,30.6,0.00677,0,0,0.6,2.1
ENSMUSG00000052033,PFDN4,prefoldin 4,nucleus|cytoplasm|mitochondrion|,biological_process|,molecular_function|,10,0.8,9.5,10,0.9,21.1,0.8,30.1,30.1,0.00727,0,0,0.5,1.2
ENSMUSG00000042079,HNRNPF,heterogeneous nuclear ribonucleoprotein F,nucleus|spliceosomal complex|membrane|ribonucleoprotein complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|regulation of RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|single-stranded RNA binding|TBP-class protein binding|poly(A) RNA binding|,9,0.9,23,9,0.8,7.3,0.9,29.9,29.9,0.00755,0,0,0.6,1.4
ENSMUSG00000029146,SNX17,sorting nexin 17,cytoplasm|cytoplasm|endosome|endosome|early endosome|Golgi apparatus|cytosol|endosome membrane|membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|protein complex|,transport|receptor-mediated endocytosis|signal transduction|protein transport|,protein binding|protein C-terminus binding|lipid binding|phosphatidylinositol binding|low-density lipoprotein particle receptor binding|,10,1,19.9,10,0.8,10.3,0.9,29.5,29.5,0.00807,0,0,0.6,1.4
ENSMUSG00000023307,5-Mar,membrane-associated ring finger (C3HC4) 5,mitochondrion|mitochondrial outer membrane|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,protein polyubiquitination|protein autoubiquitination|protein localization to mitochondrion|regulation of mitochondrial fission|positive regulation of mitochondrial fission|negative regulation of cell aging|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|GTPase binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,0.6,8.12,10,1.7,24.6,0.9,29.4,29.4,0.00817,0,0,0.5,2.2
ENSMUSG00000055371,STAM2,signal transducing adaptor molecule (SH3 domain and ITAM motif) 2,nucleus|cytoplasm|endosome|membrane|intracellular membrane-bounded organelle|,transport|intracellular protein transport|protein transport|,protein binding|,10,-0.8,13.3,10,-0.7,16.4,-0.8,29.1,-29.1,0.0085,0,0,-1.1,-0.5
ENSMUSG00000041084,OSTC,oligosaccharyltransferase complex subunit,oligosaccharyltransferase complex|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.8,26.9,10,0.6,4.43,0.7,28.4,28.4,0.00931,0,0,0.4,2.4
ENSMUSG00000003458,NCSTN,nicastrin,lysosomal membrane|endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,myeloid cell homeostasis|proteolysis|membrane protein ectodomain proteolysis|Notch signaling pathway|protein processing|T cell proliferation|positive regulation of catalytic activity|beta-amyloid metabolic process|epithelial cell proliferation|epithelial cell proliferation|,endopeptidase activity|protein binding|peptidase activity|,10,1,10.6,10,0.9,17.6,0.9,27.8,27.8,0.0102,0,0,0.5,1.3
ENSMUSG00000053119,CHMP3,charged multivesicular body protein 3,cytoplasm|endosome|early endosome|late endosome|membrane|midbody|extracellular vesicular exosome|,transport|cell cycle|endosome to lysosome transport|protein transport|positive regulation of cytokinesis|regulation of viral process|regulation of endosome size|cell division|positive regulation of viral release from host cell|,"phosphatidylinositol-4,5-bisphosphate binding|",10,-1,12.2,10,-0.9,16,-0.9,27.7,-27.7,0.0103,0,0,-1.4,-0.6
ENSMUSG00000030104,EDEM1,"ER degradation enhancer, mannosidase alpha-like 1",endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,response to unfolded protein|ER-associated ubiquitin-dependent protein catabolic process|,"mannosyl-oligosaccharide 1,2-alpha-mannosidase activity|calcium ion binding|protein binding|misfolded protein binding|",10,-0.2,0.829,10,1.6,29.2,0.9,27.7,27.7,0.0103,0,0,0.6,2.6
ENSMUSG00000032504,PDCD6IP,programmed cell death 6 interacting protein,immunological synapse|cytoplasm|cytosol|cytoskeleton|membrane|extracellular vesicular exosome|,transport|apoptotic process|cell cycle|protein transport|cell division|,protein binding|SH3 domain binding|protein homodimerization activity|protein dimerization activity|calcium-dependent protein binding|,10,1.8,29.6,10,-0.1,0.319,1.7,27.6,27.6,0.0105,0,0,1.1,2.9
ENSMUSG00000002778,KDELR1,KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1,endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|cis-Golgi network|cis-Golgi network|membrane|integral component of membrane|cytoplasmic vesicle|,protein retention in ER lumen|transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|ER retention sequence binding|,10,1,12,10,0.7,16.2,0.8,27.3,27.3,0.011,0,0,0.5,1.3
ENSMUSG00000020149,RAB1,"RAB1, member RAS oncogene family",Golgi membrane|intracellular|cell|cytoplasm|endosome|early endosome|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|melanosome|neuronal cell body|extracellular vesicular exosome|,autophagic vacuole assembly|GTP catabolic process|transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|ER to Golgi vesicle-mediated transport|endocytosis|autophagy|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|cell migration|cell migration|growth hormone secretion|melanosome transport|substrate adhesion-dependent cell spreading|defense response to bacterium|vesicle transport along microtubule|interleukin-8 secretion|,nucleotide binding|GTPase activity|protein binding|GTP binding|,10,0.6,5.4,10,1.3,24.2,1.2,27,27,0.0113,0,0,0.7,1.8
ENSMUSG00000058385,HIST1H2BG,"histone cluster 1, H2bg",extracellular space|nucleus|extracellular vesicular exosome|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,molecular_function|,2,2,27.5,2,0.1,0.0709,2,26.2,26.2,0.013,0,0,1.5,4
ENSMUSG00000035890,RNF126,ring finger protein 126,cellular_component|nucleus|cytoplasm|,biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.9,14.2,10,0.7,12.1,0.7,25.9,25.9,0.0136,0,0,0.4,1.1
ENSMUSG00000015750,APH1A,anterior pharynx defective 1a homolog (C. elegans),endoplasmic reticulum|Golgi apparatus|integral component of plasma membrane|membrane|membrane|integral component of membrane|,metanephros development|proteolysis|membrane protein ectodomain proteolysis|Notch signaling pathway|Notch receptor processing|Notch receptor processing|protein processing|protein processing|membrane protein intracellular domain proteolysis|amyloid precursor protein catabolic process|positive regulation of catalytic activity|,endopeptidase activity|endopeptidase activity|protein binding|peptidase activity|,10,0.8,13.6,10,0.6,12.7,0.7,25.5,25.5,0.0147,0,0,0.4,1.1
ENSMUSG00000015748,PRPF3,PRP3 pre-mRNA processing factor 3 homolog (yeast),nucleus|spliceosomal complex|cytoplasm|Cajal body|U4/U6 x U5 tri-snRNP complex|,"mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",identical protein binding|poly(A) RNA binding|,9,0.3,1.13,9,1.7,28.1,1.7,25.3,25.3,0.0151,0,0,0.6,2.7
ENSMUSG00000051234,RNF7,ring finger protein 7,nucleus|nucleus|cytoplasm|cytoplasm|Cul5-RING ubiquitin ligase complex|,activation of cysteine-type endopeptidase activity involved in apoptotic process|intrinsic apoptotic signaling pathway in response to oxidative stress|apoptotic mitochondrial changes|negative regulation of apoptotic process|protein neddylation|,protein binding|zinc ion binding|NEDD8 ligase activity|metal ion binding|,10,0.3,1.76,10,1.5,27.4,1.5,25.1,25.1,0.0158,0,0,0.5,2.7
ENSMUSG00000042506,USP22,ubiquitin specific peptidase 22,SAGA complex|nucleus|SAGA-type complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|ubiquitin-dependent protein catabolic process|cell cycle|chromatin modification|histone ubiquitination|histone deubiquitination|protein deubiquitination|protein deubiquitination|histone H4 acetylation|positive regulation of transcription, DNA-templated|positive regulation of mitotic cell cycle|",transcription coactivator activity|ubiquitin-specific protease activity|ubiquitin-specific protease activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|H4 histone acetyltransferase activity|hydrolase activity|enzyme binding|ligand-dependent nuclear receptor transcription coactivator activity|ubiquitinyl hydrolase activity|metal ion binding|,10,0.7,16.2,10,0.7,8.69,0.7,24.5,24.5,0.0177,0,0,0.4,1.1
ENSMUSG00000069020,URM1,ubiquitin related modifier 1 homolog (S. cerevisiae),cytoplasm|extracellular vesicular exosome|,tRNA wobble uridine modification|tRNA processing|tRNA thio-modification|,sulfurtransferase activity|,10,1.3,23.6,9,0.8,2.45,1,24.5,24.5,0.0177,0,0,0.7,1.7
ENSMUSG00000030741,SPNS1,spinster homolog 1,mitochondrion|mitochondrial inner membrane|lysosomal membrane|membrane|integral component of membrane|,transport|lipid transport|biological_process|transmembrane transport|,molecular_function|,10,0.8,7.79,10,0.9,15.5,0.8,22.8,22.8,0.0258,0,0,0.5,1.6
ENSMUSG00000078923,UBE2V1,ubiquitin-conjugating enzyme E2 variant 1,ubiquitin ligase complex|nucleus|cytoplasm|ubiquitin conjugating enzyme complex|UBC13-UEV1A complex|protein complex|extracellular vesicular exosome|,protein ubiquitination|error-free postreplication DNA repair|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of NF-kappaB transcription factor activity|protein K63-linked ubiquitination|,ubiquitin-protein transferase activity|protein binding|acid-amino acid ligase activity|ubiquitin conjugating enzyme binding|,10,-1.1,3.52,10,-1.6,20.6,-1.4,22.5,-22.5,0.0274,0,0,-2.4,-0.8
ENSMUSG00000027015,CYBRD1,cytochrome b reductase 1,membrane|integral component of membrane|brush border membrane|extracellular vesicular exosome|,transport|response to iron ion|oxidation-reduction process|,ferric-chelate reductase activity|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|epoxyqueuosine reductase activity|,9,-1.2,2.15,9,1.9,23.3,1.8,22.1,22.1,0.0296,0,0,0.9,3
ENSMUSG00000040451,SGMS1,sphingomyelin synthase 1,Golgi trans cisterna|nucleus|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|integral component of Golgi membrane|integral component of Golgi membrane|,lipid metabolic process|sphingolipid metabolic process|sphingomyelin biosynthetic process|sphingomyelin biosynthetic process|apoptotic process|inflammatory response|positive regulation of gene expression|cell growth|cell growth|phosphorylation|negative regulation of extrinsic apoptotic signaling pathway|,kinase activity|transferase activity|sphingomyelin synthase activity|sphingomyelin synthase activity|ceramide cholinephosphotransferase activity|ceramide cholinephosphotransferase activity|,10,0.6,6.21,10,1.3,17.7,0.9,22,22,0.0303,0,0,0.4,1.9
ENSMUSG00000049553,POLR1A,polymerase (RNA) I polypeptide A,nucleus|nucleus|nucleolus|DNA-directed RNA polymerase I complex|DNA-directed RNA polymerase I complex|cytoplasm|,"transcription, DNA-templated|rRNA transcription|",RNA polymerase I activity|DNA binding|DNA-directed RNA polymerase activity|protein binding|zinc ion binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,9,-1.5,19.6,8,0.9,8.55,-1.5,21.8,-21.8,0.0315,0,0,-2.8,-1.1
ENSMUSG00000039048,FOXRED1,FAD-dependent oxidoreductase domain containing 1,mitochondrion|mitochondrion|membrane|integral component of membrane|,biological_process|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.6,8.29,10,1.1,16.2,0.8,21.6,21.6,0.0328,0,0,0.5,1.5
ENSMUSG00000020571,PDIA6,protein disulfide isomerase associated 6,endoplasmic reticulum|endoplasmic reticulum lumen|smooth endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|plasma membrane|membrane|extracellular vesicular exosome|,protein folding|response to endoplasmic reticulum stress|apoptotic cell clearance|cell redox homeostasis|,protein disulfide isomerase activity|isomerase activity|,10,2.2,24.2,10,0.4,2.02,2.2,21.5,21.5,0.0336,0,0,1.1,4
ENSMUSG00000031539,AP3M2,"adaptor-related protein complex 3, mu 2 subunit",intracellular|cell|Golgi apparatus|membrane|clathrin adaptor complex|cytoplasmic vesicle|,transport|intracellular protein transport|anterograde axon cargo transport|protein transport|vesicle-mediated transport|anterograde synaptic vesicle transport|,None,10,1.9,24.9,10,-0.8,4.2,1.9,21.4,21.4,0.0347,0,0,0.9,3
ENSMUSG00000038250,USP38,ubiquitin specific peptidase 38,None,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,2.1,22.9,10,0.9,0.733,2,21.4,21.4,0.0347,0,0,1.2,4
ENSMUSG00000007850,HNRNPH1,heterogeneous nuclear ribonucleoprotein H1,nucleus|spliceosomal complex|membrane|virion|viral nucleocapsid|ribonucleoprotein complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|regulation of RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.7,5.52,10,0.8,15.9,0.8,20.9,20.9,0.0393,0,0,0.4,1.2
ENSMUSG00000031731,AP1G1,"adaptor protein complex AP-1, gamma 1 subunit",cytoplasm|Golgi apparatus|trans-Golgi network|trans-Golgi network|cytosol|microtubule cytoskeleton|membrane|membrane|membrane coat|clathrin adaptor complex|clathrin-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|recycling endosome|,microtubule cytoskeleton organization|transport|intracellular protein transport|protein transport|vesicle-mediated transport|endosome to melanosome transport|positive regulation of natural killer cell degranulation|positive regulation of natural killer cell mediated cytotoxicity|Golgi to lysosome transport|,protein binding|collagen binding|protein C-terminus binding|protein transporter activity|Rab GTPase binding|kinesin binding|GTP-dependent protein binding|,10,0.8,17.6,10,0.6,3.88,0.8,20.8,20.8,0.0402,0,0,0.5,1.4
ENSMUSG00000038805,SIX3,sine oculis-related homeobox 3,nucleus|,"eye development|transcription from RNA polymerase II promoter|protein import into nucleus|multicellular organismal development|brain development|diencephalon development|telencephalon development|forebrain anterior/posterior pattern specification|forebrain anterior/posterior pattern specification|negative regulation of Wnt signaling pathway|camera-type eye development|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|circadian behavior|lens induction in camera-type eye|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|receptor binding|protein binding|sequence-specific DNA binding|,10,0.4,0.362,10,2,23.5,1.9,20.8,20.8,0.0402,0,0,1.1,4
ENSMUSG00000020964,SEL1L,sel-1 suppressor of lin-12-like (C. elegans),endoplasmic reticulum|membrane|integral component of membrane|,Notch signaling pathway|response to endoplasmic reticulum stress|,None,10,0.8,8.66,10,1.2,12.8,0.9,20.7,20.7,0.0412,0,0,0.5,1.6
ENSMUSG00000025512,CHID1,chitinase domain containing 1,extracellular region|extracellular space|nucleus|lysosome|late endosome|trans-Golgi network|membrane|extracellular vesicular exosome|,immune system process|carbohydrate metabolic process|chitin catabolic process|innate immune response|negative regulation of cytokine production involved in inflammatory response|,"hydrolase activity, hydrolyzing O-glycosyl compounds|chitinase activity|oligosaccharide binding|",10,0,0,10,1.7,23.9,1.7,20.5,20.5,0.0433,0,0,0.9,3
ENSMUSG00000015757,PPIL4,peptidylprolyl isomerase (cyclophilin)-like 4,cellular_component|nucleus|,protein peptidyl-prolyl isomerization|protein folding|biological_process|,nucleotide binding|nucleic acid binding|RNA binding|peptidyl-prolyl cis-trans isomerase activity|isomerase activity|poly(A) RNA binding|,8,0.4,1.62,8,1.5,21.3,1.4,20.5,20.5,0.0433,0,0,0.4,2.8
ENSMUSG00000004565,PNPLA6,patatin-like phospholipase domain containing 6,endoplasmic reticulum|membrane|membrane|integral component of membrane|,angiogenesis|lipid metabolic process|metabolic process|organ morphogenesis|lipid catabolic process|phosphatidylcholine metabolic process|,lysophospholipase activity|hydrolase activity|carboxylic ester hydrolase activity|,10,0,0,10,1.6,23.7,1.6,20.4,20.4,0.0444,0,0,0.5,2.9
ENSMUSG00000056537,RLIM,"ring finger protein, LIM domain interacting",nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|ubiquitin-dependent protein catabolic process|protein ubiquitination|negative regulation of sequence-specific DNA binding transcription factor activity|random inactivation of X chromosome|random inactivation of X chromosome|","ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.5,5.91,10,0.8,15.4,0.7,20.4,20.4,0.0444,0,0,0.4,1.1
ENSMUSG00000015980,LRRC27,leucine rich repeat containing 27,cellular_component|,biological_process|,molecular_function|,10,2,23.8,10,-0.2,1.43,2,20.3,20.3,0.0455,0,0,1.2,4
ENSMUSG00000049950,RPP38,ribonuclease P/MRP 38 subunit,cellular_component|nucleus|,tRNA processing|biological_process|,molecular_function|ribonuclease P activity|hydrolase activity|,9,1.7,23.3,9,0,0,1.7,20.3,20.3,0.0455,0,0,0.5,2.9
ENSMUSG00000043929,KLHL15,kelch-like 15,cellular_component|,biological_process|,molecular_function|,10,2,23.1,10,0.2,0.418,2,20.2,20.2,0.0466,0,0,1,4
ENSMUSG00000054408,SPCS3,signal peptidase complex subunit 3 homolog (S. cerevisiae),endoplasmic reticulum|,biological_process|,molecular_function|,9,0,0,9,2.3,23.6,2.3,20.1,20.1,0.0478,0,0,1.6,4
ENSMUSG00000026806,DDX31,DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31,nucleus|,biological_process|,nucleotide binding|RNA binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,2.4,22.3,10,0.6,2.27,2.4,20.1,20.1,0.0478,0,0,1.6,4
ENSMUSG00000028677,RNF220,ring finger protein 220,cytoplasm|,protein ubiquitination|protein autoubiquitination|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.6,8.74,10,0.7,11.5,0.7,19.8,19.8,0.0515,0,0,0.4,1.1
ENSMUSG00000039328,RNF122,ring finger protein 122,cellular_component|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.1,0.179,10,1.7,22.7,1.7,19.7,19.7,0.0531,0,0,0.9,3
ENSMUSG00000028538,ST3GAL3,"ST3 beta-galactoside alpha-2,3-sialyltransferase 3",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|sialylation|,"beta-galactoside (CMP) alpha-2,3-sialyltransferase activity|N-acetyllactosaminide alpha-2,3-sialyltransferase activity|sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",9,2.7,23.1,9,0,0,2.7,19.7,19.7,0.0531,0,0,2.1,5
ENSMUSG00000025354,DNAJC14,"DnaJ (Hsp40) homolog, subfamily C, member 14",endoplasmic reticulum|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|biological_process|protein transport|,G-protein coupled receptor binding|dopamine receptor binding|,10,0.3,0.792,10,2.3,22.3,2.3,19.6,19.6,0.0544,0,0,1.6,4
ENSMUSG00000019802,SEC63,SEC63-like (S. cerevisiae),intracellular|cell|endoplasmic reticulum|membrane|integral component of membrane|,"liver development|liver development|SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational protein targeting to membrane|posttranslational protein targeting to membrane|posttranslational protein targeting to membrane|nitrogen compound metabolic process|transport|multicellular organismal aging|protein transport|posttranslational protein targeting to membrane, translocation|renal system development|",protein transporter activity|poly(A) RNA binding|,10,0.6,3.8,10,1.2,18.2,0.8,19.5,19.5,0.056,0,0,0.4,1.6
ENSMUSG00000018167,STARD3,START domain containing 3,cytoplasm|mitochondrion|lysosomal membrane|endosome|late endosome|membrane|integral component of membrane|,steroid biosynthetic process|progesterone biosynthetic process|transport|lipid transport|,molecular_function|lipid binding|,10,0,0,10,1.6,22.8,1.6,19.5,19.5,0.056,0,0,0.7,3
ENSMUSG00000030019,FBXL14,F-box and leucine-rich repeat protein 14,nucleus|cytoplasm|Golgi apparatus|,protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,ubiquitin-protein transferase activity|,10,0,0,10,1.6,22.5,1.6,19.1,19.1,0.0612,0,0,0.8,3
ENSMUSG00000044786,ZFP36,zinc finger protein 36,nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytosol|cytoplasmic stress granule|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|nuclear-transcribed mRNA poly(A) tail shortening|regulation of transcription from RNA polymerase II promoter|mRNA catabolic process|regulation of tumor necrosis factor production|negative regulation of translation involved in gene silencing by miRNA|intracellular signal transduction|response to starvation|regulation of mRNA stability|negative regulation of myeloid cell differentiation|negative regulation of inflammatory response|RNA destabilization|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|3'-UTR-mediated mRNA stabilization|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|",DNA binding|mRNA binding|mRNA binding|protein binding|AU-rich element binding|AU-rich element binding|protein kinase binding|C-C chemokine binding|mRNA 3'-UTR AU-rich region binding|poly(A) RNA binding|metal ion binding|14-3-3 protein binding|,10,0.7,15.5,10,0.5,4.78,0.6,19.1,19.1,0.0612,0,0,0.4,1.1
ENSMUSG00000022204,NGDN,"neuroguidin, EIF4E binding protein","chromosome, centromeric region|nucleus|chromosome|cytoplasm|cell projection|",regulation of translation|,poly(A) RNA binding|,9,0.9,14,8,1,5.53,1,19.1,19.1,0.0612,0,0,0.5,1.5
ENSMUSG00000060279,AP2A1,"adaptor-related protein complex 2, alpha 1 subunit",plasma membrane|coated pit|membrane|membrane|basolateral plasma membrane|apical plasma membrane|membrane coat|clathrin adaptor complex|secretory granule|protein complex|,transport|intracellular protein transport|endocytosis|protein transport|vesicle-mediated transport|negative regulation of hyaluronan biosynthetic process|,protein binding|protein C-terminus binding|protein transporter activity|,10,0.9,15.3,10,0.5,5.1,0.6,18.9,18.9,0.063,0,0,0.3,1.1
ENSMUSG00000038467,CHMP4B,charged multivesicular body protein 4B,ESCRT III complex|nucleus|cytoplasm|endosome|cytoplasmic side of plasma membrane|membrane|midbody|extracellular vesicular exosome|,posttranslational protein targeting to membrane|transport|protein transport|regulation of viral process|protein homooligomerization|negative regulation of neuron death|positive regulation of viral release from host cell|negative regulation of autophagic vacuole assembly|,identical protein binding|protein homodimerization activity|,8,-0.7,6.72,6,-1.3,13.1,-0.9,17.9,-17.9,0.0706,0,0,-1.9,-0.5
ENSMUSG00000024413,NPC1,Niemann-Pick type C1,extracellular region|nuclear envelope|nuclear envelope|lysosome|lysosomal membrane|endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|vesicle|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,protein glycosylation|protein glycosylation|lipid metabolic process|endocytosis|autophagy|adult walking behavior|steroid metabolic process|cholesterol metabolic process|negative regulation of macroautophagy|negative regulation of macroautophagy|cholesterol transport|membrane raft organization|cholesterol efflux|cholesterol efflux|response to drug|cholesterol homeostasis|response to cadmium ion|negative regulation of cell death|cellular response to steroid hormone stimulus|cellular response to low-density lipoprotein particle stimulus|establishment of protein localization to membrane|,protein binding|hedgehog receptor activity|cholesterol binding|,9,0.7,10.8,9,0.8,7.1,0.8,17.4,17.4,0.073,0,0,0.4,1.3
ENSMUSG00000035697,HMHA1,histocompatibility (minor) HA-1,intracellular|membrane|,signal transduction|intracellular signal transduction|,molecular_function|GTPase activator activity|metal ion binding|,9,0.5,3.68,9,1.2,14.8,0.6,17.3,17.3,0.0736,0,0,0.3,1.5
ENSMUSG00000028718,STIL,Scl/Tal1 interrupting locus,cytoplasm|centrosome|,embryonic axis specification|in utero embryonic development|neural tube closure|heart looping|smoothened signaling pathway|multicellular organismal development|determination of left/right symmetry|neural tube development|forebrain development|notochord development|floor plate development|multicellular organism growth|negative regulation of apoptotic process|,None,8,1.3,3.98,8,1.1,13.7,1.2,17.2,17.2,0.074,0,0,0.7,1.9
ENSMUSG00000028691,PRDX1,peroxiredoxin 1,extracellular space|nucleus|nuclear euchromatin|nucleolus|cytoplasm|mitochondrion|mitochondrial matrix|peroxisomal matrix|cytosol|extracellular vesicular exosome|,response to reactive oxygen species|response to oxidative stress|response to oxidative stress|cell proliferation|removal of superoxide radicals|regulation of stress-activated MAPK cascade|erythrocyte homeostasis|natural killer cell mediated cytotoxicity|regulation of NF-kappaB import into nucleus|hydrogen peroxide catabolic process|oxidation-reduction process|,peroxidase activity|protein binding|thioredoxin peroxidase activity|antioxidant activity|oxidoreductase activity|heme binding|identical protein binding|protein homodimerization activity|poly(A) RNA binding|peroxiredoxin activity|,10,1.5,5.06,10,1.2,12.9,1.4,17,17,0.0747,0,0,0.8,2.7
ENSMUSG00000026791,SLC2A8,"solute carrier family 2, (facilitated glucose transporter), member 8",lysosomal membrane|plasma membrane|integral component of plasma membrane|synaptic vesicle|membrane|integral component of membrane|cytoplasmic vesicle|,response to hypoxia|glucose metabolic process|transport|insulin receptor signaling pathway|carbohydrate transport|fructose transport|galactose transport|glucose transport|hexose transmembrane transport|transmembrane transport|,transporter activity|galactose transmembrane transporter activity|glucose transmembrane transporter activity|glucose binding|fructose uniporter activity|transmembrane transporter activity|substrate-specific transmembrane transporter activity|,9,0.1,0.0508,10,1.5,19.9,1.5,16.9,16.9,0.075,0,0,0.6,3
ENSMUSG00000021811,DNAJC9,"DnaJ (Hsp40) homolog, subfamily C, member 9",nucleus|,biological_process|,None,8,0.9,10.8,6,0.8,6.31,0.8,16.5,16.5,0.0763,0,0,0.4,1.4
ENSMUSG00000029993,NFU1,NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae),nucleus|cytoplasm|mitochondrion|mitochondrion|cytosol|,iron-sulfur cluster assembly|,"iron ion binding|protein binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0.7,8.22,10,0.6,8.39,0.6,16.2,16.2,0.0771,0,0,0.4,1.1
ENSMUSG00000021737,PSMD6,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 6",proteasome complex|proteasome accessory complex|extracellular vesicular exosome|,None,None,5,1.1,11.2,4,0.9,5.61,1,16.1,16.1,0.0774,0,0,0.6,1.8
ENSMUSG00000023353,AGAP3,"ArfGAP with GTPase domain, ankyrin repeat and PH domain 3",intracellular|cell|nucleus|cytoplasm|membrane|PML body|cell periphery|,"protein import into nucleus, translocation|GTP catabolic process|signal transduction|small GTPase mediated signal transduction|PML body organization|regulation of ARF GTPase activity|cellular response to reactive oxygen species|cellular response to reactive oxygen species|cellular response to UV|proteasome-mediated ubiquitin-dependent protein catabolic process|",nucleotide binding|GTPase activity|GTPase activator activity|GTP binding|ARF GTPase activator activity|zinc ion binding|polyubiquitin binding|metal ion binding|,10,0.7,3.58,10,1.4,13.7,1.1,16,16,0.0778,0,0,0.3,2.3
ENSMUSG00000028277,UBE2J1,ubiquitin-conjugating enzyme E2J 1,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,protein ubiquitination|protein N-linked glycosylation via asparagine|ER-associated ubiquitin-dependent protein catabolic process|,nucleotide binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0.7,5.2,10,0.7,11.2,0.7,16,16,0.0778,0,0,0.4,1.2
ENSMUSG00000005696,SH2D1A,SH2 domain containing 1A,cytoplasm|,humoral immune response|cellular defense response|cell-cell signaling|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|,SH3/SH2 adaptor activity|protein binding|,10,-1.4,19.1,10,0.5,1.43,-1.4,15.9,-15.9,0.0781,0,0,-3,-0.9
ENSMUSG00000079722,TTLL2,"tubulin tyrosine ligase-like family, member 2",cellular_component|,cellular protein modification process|biological_process|,molecular_function|ligase activity|,10,-0.1,0.0431,10,1.4,18.2,0.4,15.7,15.7,0.0789,0,0,0.3,2.7
ENSMUSG00000002111,SPI1,spleen focus forming virus (SFFV) proviral integration oncogene,nuclear chromatin|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|vasculature development|lymphoid progenitor cell differentiation|myeloid leukocyte differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|lymphocyte differentiation|erythrocyte differentiation|macrophage differentiation|granulocyte differentiation|somatic stem cell maintenance|myeloid dendritic cell differentiation|negative regulation of MHC class II biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|anatomical structure regression|apoptotic process involved in patterning of blood vessels|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA binding|protein binding|sequence-specific DNA binding|NFAT protein binding|,7,0.9,11,6,0.7,5.48,0.8,15.6,15.6,0.0792,0,0,0.4,1.5
ENSMUSG00000006095,TBCB,tubulin folding cofactor B,nucleus|cytoplasm|cytoskeleton|microtubule|,multicellular organismal development|nervous system development|cell differentiation|,protein binding|,8,0.2,0.826,8,1.1,17.2,1.1,15.5,15.5,0.0797,0,0,0.5,1.8
ENSMUSG00000021134,SRSF5,serine/arginine-rich splicing factor 5,nucleus|nuclear speck|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|response to wounding|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|RS domain binding|,10,-0.9,14.7,10,-0.5,2.42,-0.8,15.5,-15.5,0.0797,0,0,-1.3,-0.4
ENSMUSG00000022234,CCT5,"chaperonin containing Tcp1, subunit 5 (epsilon)",zona pellucida receptor complex|nucleolus|cytoplasm|centrosome|chaperonin-containing T-complex|cytoskeleton|microtubule|cell body|extracellular vesicular exosome|,protein folding|binding of sperm to zona pellucida|cellular protein metabolic process|,nucleotide binding|protein binding|ATP binding|G-protein beta-subunit binding|unfolded protein binding|,6,1.4,7.14,7,0.8,9.65,0.9,15.3,15.3,0.0805,0,0,0.5,1.8
ENSMUSG00000037653,KCTD8,potassium channel tetramerisation domain containing 8,plasma membrane|membrane|cell junction|receptor complex|synapse|postsynaptic membrane|,regulation of G-protein coupled receptor protein signaling pathway|protein homooligomerization|,molecular_function|,10,1.1,17.2,10,-0.1,0.0387,1,15.2,15.2,0.0809,0,0,0.6,1.8
ENSMUSG00000021870,SLMAP,sarcolemma associated protein,extracellular space|cytoplasm|cytoskeleton|plasma membrane|membrane|integral component of membrane|,None,protein binding|,10,0.5,2.37,10,0.8,13.9,0.7,15.2,15.2,0.0809,0,0,0.4,1.3
ENSMUSG00000022898,DSCR3,Down syndrome critical region gene 3,nucleus|,None,None,10,0.8,11.7,10,0.6,4.32,0.7,15.2,15.2,0.0809,0,0,0.4,1.2
ENSMUSG00000020659,CBLL1,Casitas B-lineage lymphoma-like 1,cellular_component|,negative regulation of cell adhesion|single organismal cell-cell adhesion|protein ubiquitination|positive regulation of cell migration|positive regulation of endocytosis|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|identical protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.9,6.83,10,0.8,8.89,0.8,15.2,15.2,0.0809,0,0,0.5,1.6
ENSMUSG00000022262,DNAH5,"dynein, axonemal, heavy chain 5",cytoplasm|cytoskeleton|axonemal dynein complex|microtubule|cilium|axoneme|axoneme|dynein complex|cell projection|,cilium movement|microtubule-based movement|lateral ventricle development|left/right axis specification|,nucleotide binding|motor activity|microtubule motor activity|ATP binding|ATPase activity|,9,1.7,16.5,9,0.5,3.31,1.6,15.1,15.1,0.0813,0,0,0.3,2.8
ENSMUSG00000026867,GAPVD1,GTPase activating protein and VPS9 domains 1,intracellular|endosome|cytosol|cytosol|membrane|,endocytosis|signal transduction|positive regulation of GTPase activity|positive regulation of GTPase activity|regulation of small GTPase mediated signal transduction|regulation of protein transport|regulation of protein transport|,guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|GTPase activating protein binding|GTPase activating protein binding|,10,0.6,8.23,10,0.6,7.06,0.6,14.9,14.9,0.0821,0,0,0.3,1
ENSMUSG00000002129,SF3A1,"splicing factor 3a, subunit 1",nucleus|spliceosomal complex|U2-type spliceosomal complex|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|RNA processing|mRNA processing|RNA splicing|",RNA binding|poly(A) RNA binding|,6,1.5,13.1,7,1,2.53,1.1,14.7,14.7,0.0827,0,0,0.6,2.6
ENSMUSG00000022174,DAD1,defender against cell death 1,endoplasmic reticulum|oligosaccharyltransferase complex|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,blastocyst development|apoptotic process|negative regulation of apoptotic process|,"dolichyl-diphosphooligosaccharide-protein glycotransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",9,-0.9,6.05,9,-1.2,9.35,-0.9,14.6,-14.6,0.083,0,0,-1.7,-0.5
ENSMUSG00000039771,POLR2J,polymerase (RNA) II (DNA directed) polypeptide J,"nucleus|nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II activity|DNA binding|DNA-directed RNA polymerase activity|protein binding|LRR domain binding|protein dimerization activity|,8,-1.5,16.9,8,0.1,0.0684,-1.4,14.5,-14.5,0.0834,0,0,-2.6,-0.7
ENSMUSG00000030534,VPS33B,vacuolar protein sorting 33B (yeast),cytoplasm|lysosome|endosome|late endosome|membrane|HOPS complex|platelet alpha granule|perinuclear region of cytoplasm|,transport|vesicle docking involved in exocytosis|protein transport|vesicle-mediated transport|melanosome localization|lysosome localization|membrane fusion|platelet alpha granule organization|,protein binding|,9,0.5,6.33,10,0.7,8.7,0.6,14.3,14.3,0.084,0,0,0.3,1.3
ENSMUSG00000020719,DDX5,DEAD (Asp-Glu-Ala-Asp) box polypeptide 5,nucleus|nucleus|spliceosomal complex|membrane|ribonucleoprotein complex|extracellular vesicular exosome|catalytic step 2 spliceosome|,"negative regulation of transcription from RNA polymerase II promoter|regulation of alternative mRNA splicing, via spliceosome|in utero embryonic development|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|circadian rhythm|RNA splicing|positive regulation of intracellular estrogen receptor signaling pathway|positive regulation of DNA damage response, signal transduction by p53 class mediator|regulation of viral genome replication|regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|regulation of androgen receptor signaling pathway|intrinsic apoptotic signaling pathway by p53 class mediator|regulation of skeletal muscle cell differentiation|","nucleotide binding|nucleic acid binding|transcription cofactor activity|transcription coactivator activity|RNA binding|RNA helicase activity|ATP-dependent RNA helicase activity|helicase activity|protein binding|calmodulin binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|enzyme binding|estrogen receptor binding|pre-mRNA binding|poly(A) RNA binding|calcium-dependent protein binding|androgen receptor binding|",7,1,15.2,7,0.3,1.55,0.9,14.2,14.2,0.0845,0,0,0.4,2.2
ENSMUSG00000026172,BCS1L,BCS1-like (yeast),mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,mitochondrion organization|mitochondrial respiratory chain complex I assembly|mitochondrial respiratory chain complex IV assembly|mitochondrial respiratory chain complex III assembly|mitochondrial respiratory chain complex III assembly|,nucleotide binding|ATP binding|,10,-0.3,0.321,10,1,16.1,0.9,13.9,13.9,0.0857,0,0,0.4,1.7
ENSMUSG00000000216,SCNN1G,"sodium channel, nonvoltage-gated 1 gamma",plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|sodium channel complex|sodium channel complex|extracellular vesicular exosome|,"transport|ion transport|sodium ion transport|sodium ion transport|sodium ion transport|wound healing, spreading of epidermal cells|sodium ion transmembrane transport|sodium ion transmembrane transport|multicellular organismal water homeostasis|response to stimulus|sensory perception of taste|sodium ion homeostasis|",sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|WW domain binding|WW domain binding|,9,0.3,0.782,10,1.3,16.2,1.3,13.9,13.9,0.0857,0,0,0.3,2.5
ENSMUSG00000033653,VPS8,vacuolar protein sorting 8 homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.4,2.85,10,1.1,14.1,1,13.8,13.8,0.086,0,0,0.3,1.7
ENSMUSG00000040374,PEX2,peroxisomal biogenesis factor 2,peroxisome|peroxisomal membrane|integral component of peroxisomal membrane|membrane|integral component of membrane|Cdc73/Paf1 complex|,very long-chain fatty acid metabolic process|negative regulation of transcription from RNA polymerase II promoter|neuron migration|fatty acid beta-oxidation|bile acid biosynthetic process|peroxisome organization|nervous system development|protein import into peroxisome matrix|protein destabilization|cholesterol homeostasis|regulation of cholesterol biosynthetic process|negative regulation of fibroblast proliferation|negative regulation of epithelial cell proliferation|,zinc ion binding|metal ion binding|,10,0.7,6.93,10,0.5,7.4,0.6,13.8,13.8,0.086,0,0,0.3,1.1
ENSMUSG00000028902,SF3A3,"splicing factor 3a, subunit 3",nucleus|spliceosomal complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,nucleic acid binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,6,0.7,8.86,6,1.1,5.77,0.8,13.6,13.6,0.0869,0,0,0.4,1.7
ENSMUSG00000035354,UVRAG,UV radiation resistance associated gene,lysosome|early endosome|late endosome|protein complex|phagocytic vesicle|,SNARE complex assembly|viral entry into host cell|,SNARE binding|protein binding|SH3 domain binding|,10,0.5,3.74,10,0.7,10.5,0.7,13.6,13.6,0.0869,0,0,0.3,1.1
ENSMUSG00000035521,GNPTG,"N-acetylglucosamine-1-phosphotransferase, gamma subunit",Golgi membrane|extracellular region|Golgi apparatus|membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,N-glycan processing to lysosome|carbohydrate phosphorylation|,UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity|protein homodimerization activity|,10,0.7,1.76,10,1.1,12.1,0.8,13.4,13.4,0.0876,0,0,0.3,1.7
ENSMUSG00000021391,CENPP,centromere protein P,"chromosome, centromeric region|cellular_component|nucleus|chromosome|",biological_process|centromere-specific nucleosome assembly|,molecular_function|,10,1.4,3.48,10,0.7,11.2,1.2,13.3,13.3,0.088,0,0,0.4,1.9
ENSMUSG00000022136,DNAJC3,"DnaJ (Hsp40) homolog, subfamily C, member 3",cytoplasm|endoplasmic reticulum|endoplasmic reticulum lumen|smooth endoplasmic reticulum|cytosol|membrane|endoplasmic reticulum Sec complex|extracellular vesicular exosome|,negative regulation of protein kinase activity|response to unfolded protein|endoplasmic reticulum unfolded protein response|proteolysis involved in cellular protein catabolic process|,protein kinase inhibitor activity|protein binding|chaperone binding|misfolded protein binding|,10,-0.4,2.93,10,-0.9,12.3,-0.7,13.2,-13.2,0.0884,0,0,-1.4,-0.4
ENSMUSG00000021686,AP3B1,"adaptor-related protein complex 3, beta 1 subunit",intracellular|cell|lysosomal membrane|Golgi apparatus|trans-Golgi network|membrane|membrane|membrane coat|AP-3 adaptor complex|cytoplasmic vesicle|,"protein targeting to lysosome|transport|zinc ion transport|intracellular protein transport|blood coagulation|anterograde axon cargo transport|protein transport|vesicle-mediated transport|antigen processing and presentation|melanosome organization|antigen processing and presentation, exogenous lipid antigen via MHC class Ib|anterograde synaptic vesicle transport|positive regulation of NK T cell differentiation|",protein phosphatase binding|GTP-dependent protein binding|,10,0.7,14.8,10,0.2,0.384,0.7,13.2,13.2,0.0884,0,0,0.3,1.2
ENSMUSG00000039367,SEC24C,"Sec24 related gene family, member C (S. cerevisiae)",None,transport|protein transport|,None,10,1.6,10.9,10,1.2,3.19,1.6,13.1,13.1,0.0888,0,0,0.9,2.9
ENSMUSG00000001143,LMAN2L,"lectin, mannose-binding 2-like",endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|,protein transport|,molecular_function|metal ion binding|,10,1.6,13.5,10,0.6,1.6,1.1,13,13,0.0892,0,0,0.3,2.6
ENSMUSG00000014504,SRP19,signal recognition particle 19,"nucleus|nucleolus|cytoplasm|mitochondrion|signal recognition particle, endoplasmic reticulum targeting|ribonucleoprotein complex|signal recognition particle|",SRP-dependent cotranslational protein targeting to membrane|response to drug|,RNA binding|7S RNA binding|poly(A) RNA binding|,9,0.9,8.73,9,0.6,4.86,0.8,13,13,0.0892,0,0,0.3,1.4
ENSMUSG00000040774,CEPT1,choline/ethanolaminephosphotransferase 1,nucleus|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,lipid metabolic process|phosphatidylcholine biosynthetic process|phospholipid biosynthetic process|,"diacylglycerol cholinephosphotransferase activity|ethanolaminephosphotransferase activity|transferase activity|phosphotransferase activity, for other substituted phosphate groups|metal ion binding|",9,-1.2,2.14,7,1.3,14.4,1.3,12.9,12.9,0.0896,0,0,0.3,2.6
ENSMUSG00000028920,FBXO42,F-box protein 42,cellular_component|,biological_process|,molecular_function|,10,-0.5,5.87,9,-0.9,9.34,-0.7,12.8,-12.8,0.0902,0,0,-1.3,-0.3
ENSMUSG00000032405,PIAS1,protein inhibitor of activated STAT 1,intracellular|nucleus|nucleus|PML body|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|JAK-STAT cascade|protein sumoylation|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of protein sumoylation|regulation of cell proliferation|positive regulation of transcription, DNA-templated|positive regulation of smooth muscle cell differentiation|protein-DNA complex assembly|regulation of RNA biosynthetic process|","nucleic acid binding|DNA binding|transcription corepressor activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|enzyme binding|protein domain specific binding|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1,9.92,10,1,3.09,1,12.7,12.7,0.0907,0,0,0.3,2
ENSMUSG00000029577,UBE3B,ubiquitin protein ligase E3B,nucleus|cytoplasm|,protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,-1.3,10.2,10,-0.5,5.71,-1,12.2,-12.2,0.093,0,0,-1.7,-0.3
ENSMUSG00000019087,ATP6AP1,"ATPase, H+ transporting, lysosomal accessory protein 1","vacuole|membrane|integral component of membrane|proton-transporting V-type ATPase, V1 domain|extracellular vesicular exosome|",transport|ion transport|cell death|ATP hydrolysis coupled proton transport|proton transport|,"nucleotide binding|ATP binding|proton-transporting ATP synthase activity, rotational mechanism|proton-transporting ATPase activity, rotational mechanism|",10,0.8,10,10,0.6,2.76,0.7,12.2,12.2,0.093,0,0,0.3,1.2
ENSMUSG00000021713,PPWD1,peptidylprolyl isomerase domain and WD repeat containing 1,nucleus|spliceosomal complex|catalytic step 2 spliceosome|,protein peptidyl-prolyl isomerization|mRNA processing|protein folding|biological_process|RNA splicing|,molecular_function|peptidyl-prolyl cis-trans isomerase activity|isomerase activity|,8,-0.8,9.58,5,-1,3.23,-0.9,12.2,-12.2,0.093,0,0,-1.7,-0.5
ENSMUSG00000066637,TTC32,tetratricopeptide repeat domain 32,cellular_component|,biological_process|,molecular_function|,9,1.6,13.9,8,0.2,0.229,1.5,12.1,12.1,0.0935,0,0,0.4,2.8
ENSMUSG00000046679,C87436,expressed sequence C87436,cellular_component|,biological_process|,molecular_function|,10,-1.2,2.77,10,1.4,15.5,1.4,12.1,12.1,0.0935,0,0,0.3,2.8
ENSMUSG00000024807,SYVN1,"synovial apoptosis inhibitor 1, synoviolin",ubiquitin ligase complex|nucleus|endoplasmic reticulum|membrane|membrane|integral component of membrane|,in utero embryonic development|response to unfolded protein|multicellular organismal development|protein ubiquitination|protein N-linked glycosylation via asparagine|ER-associated ubiquitin-dependent protein catabolic process|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.7,9.33,10,0.6,2.96,0.7,11.9,11.9,0.0943,0,0,0.2,1.1
ENSMUSG00000069300,HIST1H2BJ,"histone cluster 1, H2bj",nucleus|extracellular vesicular exosome|,biological_process|,molecular_function|,7,-0.2,0.497,7,1,14.5,0.9,11.8,11.8,0.0948,0,0,0.5,1.8
ENSMUSG00000006057,ATP5G1,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)","mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|integral component of membrane|proton-transporting two-sector ATPase complex, proton-transporting domain|proton-transporting ATP synthase complex, coupling factor F(o)|",transport|ion transport|ATP synthesis coupled proton transport|ATP hydrolysis coupled proton transport|proton transport|ATP metabolic process|,lipid binding|hydrogen ion transmembrane transporter activity|,10,0.9,6.49,10,1.2,6.3,0.9,11.8,11.8,0.0948,0,0,0.4,1.8
ENSMUSG00000020219,TIMM13,translocase of inner mitochondrial membrane 13,nucleolus|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|,transport|protein transport|,metal ion binding|,10,0.9,13.4,9,0,0,0.9,11.8,11.8,0.0948,0,0,0.4,1.6
ENSMUSG00000028757,DDOST,dolichyl-di-phosphooligosaccharide-protein glycotransferase,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|protein complex|,protein N-linked glycosylation|protein N-linked glycosylation via asparagine|response to cytokine|T cell activation|,"dolichyl-diphosphooligosaccharide-protein glycotransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",9,-0.8,4.71,8,0.8,8.94,0.9,11.5,11.5,0.0965,0,0,0.4,1.8
ENSMUSG00000081058,HIST2H3C2,"histone cluster 2, H3c2",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,molecular_function|,8,0.8,3.69,8,1.3,9.31,1.2,11.5,11.5,0.0965,0,0,0.5,2
ENSMUSG00000006517,MVD,mevalonate (diphospho) decarboxylase,peroxisome|peroxisomal matrix|cytosol|,"lipid metabolic process|steroid biosynthetic process|cholesterol biosynthetic process|steroid metabolic process|cholesterol metabolic process|positive regulation of cell proliferation|isoprenoid biosynthetic process|sterol biosynthetic process|isopentenyl diphosphate biosynthetic process, mevalonate pathway|",nucleotide binding|diphosphomevalonate decarboxylase activity|ATP binding|lyase activity|carboxy-lyase activity|Hsp70 protein binding|protein homodimerization activity|,9,0.4,1.48,9,1.4,13.5,1.3,11.4,11.4,0.097,0,0,0.3,2.8
ENSMUSG00000069302,HIST1H2AH,"histone cluster 1, H2ah",nucleosome|nucleus|chromosome|extracellular vesicular exosome|,biological_process|,DNA binding|protein heterodimerization activity|,6,1.3,3.81,6,1,8.39,1.1,11.4,11.4,0.097,0,0,0.5,1.9
ENSMUSG00000029458,BRAP,BRCA1 associated protein,ubiquitin ligase complex|cytoplasm|nuclear membrane|,MAPK cascade|Ras protein signal transduction|negative regulation of signal transduction|protein ubiquitination|,"nucleotide binding|ubiquitin-protein transferase activity|nuclear localization sequence binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,-0.9,2.54,10,1.3,12.7,0.6,11.2,11.2,0.0984,0,0,0.2,2.6
ENSMUSG00000020781,TSEN54,tRNA splicing endonuclease 54 homolog (S. cerevisiae),cellular_component|nucleus|,"tRNA splicing, via endonucleolytic cleavage and ligation|mRNA processing|tRNA processing|",molecular_function|,7,0.4,0.509,7,1.2,12.9,1.1,11.2,11.2,0.0984,0,0,0.5,2
ENSMUSG00000032583,MON1A,MON1 homolog A (yeast),cell|,cellular iron ion homeostasis|protein secretion|protein transport|,molecular_function|,10,-0.7,9.42,10,-1.1,2.66,-0.7,11.1,-11.1,0.099,0,0,-1.4,-0.3
ENSMUSG00000028871,RSPO1,R-spondin homolog (Xenopus laevis),extracellular region|extracellular space|nucleus|,positive regulation of protein phosphorylation|regulation of receptor internalization|male meiosis|regulation of gene expression|Wnt signaling pathway|positive regulation of Wnt signaling pathway|response to stimulus|canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|positive regulation of non-canonical Wnt signaling pathway|regulation of male germ cell proliferation|,G-protein coupled receptor binding|receptor binding|receptor binding|protein binding|heparin binding|,10,-1.4,5.87,10,-1.3,5.65,-1.3,11.1,-11.1,0.099,0,0,-2.6,-0.4
ENSMUSG00000029265,DR1,down-regulator of transcription 1,intracellular|nucleus|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|histone H3 acetylation|",DNA binding|protein binding|TBP-class protein binding|sequence-specific DNA binding|protein heterodimerization activity|,7,1.4,13.1,7,-0.5,1.14,1,11.1,11.1,0.099,0,0,0.4,2.6
ENSMUSG00000020863,LUC7L3,LUC7-like 3 (S. cerevisiae),nucleus|U1 snRNP|plasma membrane|focal adhesion|,mRNA splice site selection|mRNA processing|RNA splicing|,DNA binding|mRNA binding|poly(A) RNA binding|,6,0.8,9.51,6,1,2,0.9,11,11,0.0995,0,0,0.4,1.8
ENSMUSG00000042699,DHX9,DEAH (Asp-Glu-Ala-His) box polypeptide 9,nucleus|nucleolus|cytoplasm|centrosome|membrane|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|CRD-mediated mRNA stability complex|,osteoblast differentiation|circadian rhythm|cellular response to heat|rhythmic process|CRD-mediated mRNA stabilization|,nucleotide binding|RNA polymerase II transcription factor binding|nucleic acid binding|DNA binding|RNA binding|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,0.9,6.8,9,0.8,4.45,0.8,10.8,10.8,0.101,0,0,0.3,1.5
ENSMUSG00000025047,PDCD11,programmed cell death 11,intracellular|nucleus|cytosol|,"regulation of transcription, DNA-templated|rRNA processing|RNA processing|mRNA processing|apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|",RNA binding|transcription factor binding|poly(A) RNA binding|,8,1,12.7,7,-1.4,4.33,0.9,10.7,10.7,0.101,0,0,0.6,2
ENSMUSG00000030357,FKBP4,FK506 binding protein 4,nucleus|nucleus|cytoplasm|mitochondrion|endoplasmic reticulum membrane|cytosol|cytoskeleton|microtubule|neuron projection|neuronal cell body|protein complex|axonal growth cone|perinuclear region of cytoplasm|extracellular vesicular exosome|,protein peptidyl-prolyl isomerization|protein peptidyl-prolyl isomerization|protein folding|steroid hormone receptor complex assembly|copper ion transport|embryo implantation|androgen receptor signaling pathway|prostate gland development|negative regulation of microtubule polymerization|protein complex localization|male sex differentiation|reproductive structure development|chaperone-mediated protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|peptidyl-prolyl cis-trans isomerase activity|protein binding|ATP binding|GTP binding|FK506 binding|isomerase activity|heat shock protein binding|heat shock protein binding|copper-dependent protein binding|glucocorticoid receptor binding|poly(A) RNA binding|tau protein binding|phosphoprotein binding|,10,1.6,11.1,10,0.7,2.08,1.5,10.6,10.6,0.102,0,0,0.3,2.8
ENSMUSG00000028555,TTC39A,tetratricopeptide repeat domain 39A,cellular_component|,biological_process|,molecular_function|,10,-1.4,13.9,10,0,0,-1.4,10.6,-10.6,0.102,0,0,-2.8,-0.5
ENSMUSG00000036371,SERBP1,serpine1 mRNA binding protein 1,nucleus|cytoplasm|membrane|extracellular vesicular exosome|,None,RNA binding|mRNA 3'-UTR binding|poly(A) RNA binding|,9,-1.7,5.84,9,1.1,9.55,0.9,10.4,10.4,0.103,0,0,0.2,1.9
ENSMUSG00000003868,RUVBL2,RuvB-like protein 2,Swr1 complex|intracellular|nucleus|nuclear euchromatin|cytoplasm|ribonucleoprotein complex|Ino80 complex|NuA4 histone acetyltransferase complex|extracellular vesicular exosome|MLL1 complex|,"ATP catabolic process|DNA repair|DNA recombination|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|chromatin modification|DNA duplex unwinding|cellular response to UV|positive regulation of histone acetylation|histone H4 acetylation|histone H2A acetylation|positive regulation of transcription from RNA polymerase II promoter|establishment of protein localization to chromatin|cellular response to estradiol stimulus|transcriptional activation by promoter-enhancer looping|negative regulation of estrogen receptor binding|",nucleotide binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|DNA helicase activity|damaged DNA binding|helicase activity|ATP binding|hydrolase activity|ATPase activity|chromatin DNA binding|identical protein binding|ATP-dependent 5'-3' DNA helicase activity|,7,0.9,9.01,7,0.8,1.73,0.9,10.3,10.3,0.104,0,0,0.3,1.7
ENSMUSG00000020372,GNB2L1,"guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1",phagocytic cup|intracellular|nucleus|cytoplasm|cytoplasm|mitochondrion|cytosol|cytoskeleton|plasma membrane|small ribosomal subunit|membrane|dendrite|midbody|cell projection|neuronal cell body|perinuclear region of cytoplasm|extracellular vesicular exosome|,osteoblast differentiation|positive regulation of protein phosphorylation|regulation of translation|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell cycle|multicellular organismal development|gastrulation|protein localization|negative regulation of gene expression|negative regulation of translation|negative regulation of cell growth|positive regulation of cell migration|positive regulation of cAMP catabolic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of protein homooligomerization|intracellular signal transduction|regulation of growth|positive regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of GTPase activity|rhythmic process|negative regulation of phagocytosis|positive regulation of cyclic-nucleotide phosphodiesterase activity|regulation of cell cycle|negative regulation of protein kinase B signaling|positive regulation of mitochondrial depolarization|negative regulation of protein tyrosine kinase activity|regulation of establishment of protein localization to plasma membrane|negative regulation of hydrogen peroxide-mediated programmed cell death|positive regulation of intrinsic apoptotic signaling pathway|,receptor activity|protein kinase C binding|protein kinase C binding|protein binding|ion channel inhibitor activity|cysteine-type endopeptidase activator activity involved in apoptotic process|enzyme binding|protein phosphatase binding|protein tyrosine kinase inhibitor activity|receptor tyrosine kinase binding|SH2 domain binding|protein homodimerization activity|poly(A) RNA binding|,6,1.3,3.23,4,0.9,8.06,1.1,10.3,10.3,0.104,0,0,0.6,2
ENSMUSG00000070699,SARS2,seryl-aminoacyl-tRNA synthetase 2,cytoplasm|mitochondrion|,translation|tRNA aminoacylation for protein translation|seryl-tRNA aminoacylation|,nucleotide binding|aminoacyl-tRNA ligase activity|serine-tRNA ligase activity|ATP binding|ligase activity|poly(A) RNA binding|,9,-0.9,8.22,9,-0.8,2.5,-0.9,10.2,-10.2,0.105,0,0,-1.6,-0.3
ENSMUSG00000063870,CHD4,chromodomain helicase DNA binding protein 4,nuclear chromatin|nucleus|nucleus|nucleoplasm|cytoplasm|centrosome|cytoskeleton|membrane|NuRD complex|NuRD complex|protein complex|protein complex|,"chromatin organization|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|ATP-dependent chromatin remodeling|spindle assembly|","nucleotide binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II repressing transcription factor binding|nucleic acid binding|DNA binding|helicase activity|protein binding|ATP binding|microtubule binding|ATP-dependent helicase activity|transcription factor binding|zinc ion binding|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|nucleosomal DNA binding|metal ion binding|",10,1.3,2.48,10,-0.8,8.64,-0.8,10.1,-10.1,0.106,0,0,-1.7,-0.3
ENSMUSG00000033364,USP37,ubiquitin specific peptidase 37,nucleus|,G1/S transition of mitotic cell cycle|proteolysis|ubiquitin-dependent protein catabolic process|cell cycle|mitotic nuclear division|protein deubiquitination|protein K11-linked deubiquitination|cell division|protein K48-linked deubiquitination|,cysteine-type endopeptidase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|protein kinase binding|ubiquitinyl hydrolase activity|,9,-0.8,3.54,9,0.7,7.91,0.7,9.87,9.87,0.108,0,0,0.3,1.9
ENSMUSG00000048833,SLC39A9,"solute carrier family 39 (zinc transporter), member 9",cellular_component|membrane|integral component of membrane|,transport|ion transport|zinc ion transport|biological_process|metal ion transport|transmembrane transport|,molecular_function|metal ion transmembrane transporter activity|,10,0.5,4.91,10,0.6,5.42,0.5,9.84,9.84,0.108,0,0,0.2,1
ENSMUSG00000025351,CD63,CD63 antigen,"cytoplasm|lysosome|lysosome|lysosomal membrane|endosome|late endosome|plasma membrane|cell surface|endosome membrane|membrane|integral component of membrane|intrinsic component of plasma membrane|late endosome membrane|protein complex|extracellular vesicular exosome|multivesicular body, internal vesicle|",positive regulation of receptor internalization|transport|cell-matrix adhesion|negative regulation of epithelial cell migration|protein transport|cell migration|epithelial cell differentiation|cellular protein localization|endosome to melanosome transport|pigmentation|positive regulation of cell adhesion|positive regulation of endocytosis|pigment granule maturation|pigment cell differentiation|regulation of vascular endothelial growth factor signaling pathway|regulation of vascular endothelial growth factor signaling pathway|regulation of rubidium ion transport|positive regulation of integrin-mediated signaling pathway|,protein binding|protein complex binding|,10,1.1,12.8,10,0,0,1.1,9.67,9.67,0.109,0,0,0.5,1.9
ENSMUSG00000024826,DPF2,"D4, zinc and double PHD fingers family 2",nuclear chromatin|nucleus|nucleus|cytoplasm|cytoplasm|centrosome|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|zinc ion binding|metal ion binding|,10,-0.1,0.307,10,0.7,11.3,0.6,9.67,9.67,0.109,0,0,0.2,1.7
ENSMUSG00000029462,VPS29,vacuolar protein sorting 29 (S. pombe),intracellular|cell|cytoplasm|endosome|membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,transport|Golgi to vacuole transport|protein transport|,phosphoserine phosphatase activity|hydrolase activity|metal ion binding|,9,1.4,10.5,9,-0.6,1.73,1.3,9.63,9.63,0.11,0,0,0.7,2
ENSMUSG00000032783,TROAP,trophinin associated protein,cellular_component|cytoplasm|,cell adhesion|biological_process|,molecular_function|,10,0.9,7.45,10,0.5,3.22,0.6,9.59,9.59,0.11,0,0,0.2,1.3
ENSMUSG00000054611,KDM2A,lysine (K)-specific demethylase 2A,nuclear chromatin|nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|oxidation-reduction process|histone H3-K36 demethylation|",DNA binding|zinc ion binding|oxidoreductase activity|unmethylated CpG binding|metal ion binding|dioxygenase activity|histone demethylase activity (H3-K36 specific)|,10,0.4,2.14,10,0.8,8.76,0.6,9.52,9.52,0.111,0,0,0.2,1.3
ENSMUSG00000001774,CHORDC1,"cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1",None,response to stress|regulation of centrosome duplication|chaperone-mediated protein folding|regulation of cellular response to heat|negative regulation of Rho-dependent protein serine/threonine kinase activity|,zinc ion binding|metal ion binding|Hsp90 protein binding|,10,0.9,5.77,10,0.5,4.86,0.8,9.5,9.5,0.111,0,0,0.3,1.5
ENSMUSG00000049620,PRSS33,"protease, serine 33",extracellular region|extracellular space|,proteolysis|proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,0.1,0.058,10,1.2,11.6,0.8,9.25,9.25,0.113,0,0,0.2,1.8
ENSMUSG00000030835,NOMO1,nodal modulator 1,endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,biological_process|,molecular_function|carbohydrate binding|,10,0.4,2.16,10,0.8,8.75,0.6,9.19,9.19,0.114,0,0,0.2,1.3
ENSMUSG00000054046,KLK13,kallikrein related-peptidase 13,extracellular space|cytoplasm|secretory granule|extracellular vesicular exosome|,proteolysis|protein processing|,endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,1.4,12.5,1.4,9.12,9.12,0.114,0,0,0.3,2.9
ENSMUSG00000035754,WDR18,WD repeat domain 18,cellular_component|nucleus|cytoplasm|,multicellular organismal development|biological_process|,molecular_function|,8,1.1,5.61,6,0.7,4.09,0.8,9.05,9.05,0.115,0,0,0.3,1.9
ENSMUSG00000038312,EDEM2,"ER degradation enhancer, mannosidase alpha-like 2",cellular_component|,biological_process|,molecular_function|,10,0.6,6.78,10,0.4,2.99,0.5,9.01,9.01,0.115,0,0,0.1,1.2
ENSMUSG00000060992,COPZ1,"coatomer protein complex, subunit zeta 1",cytoplasm|Golgi apparatus|membrane|membrane coat|COPI vesicle coat|COPI-coated vesicle|cytoplasmic vesicle|,transport|intracellular protein transport|intra-Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,molecular_function|,7,-0.1,0.00788,6,1.3,11.8,1.3,8.9,8.9,0.117,0,0,0.4,2
ENSMUSG00000028478,CLTA,"clathrin, light polypeptide (Lca)",coated pit|membrane|membrane|cytoplasmic membrane-bounded vesicle|clathrin coat|clathrin coat of trans-Golgi network vesicle|clathrin coat of coated pit|clathrin-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|clathrin complex|,intracellular protein transport|vesicle-mediated transport|,structural molecule activity|clathrin heavy chain binding|peptide binding|,9,-0.7,8.49,9,-0.3,2.11,-0.6,8.86,-8.86,0.117,0,0,-1.3,-0.2
ENSMUSG00000059323,TONSL,"tonsoku-like, DNA repair protein",nucleus|DNA replication factor A complex|cytoplasm|FACT complex|MCM complex|nuclear replication fork|,double-strand break repair via homologous recombination|DNA repair|cellular response to DNA damage stimulus|replication fork processing|,histone binding|,3,0.4,1.74,5,-1.2,10.6,-1.2,8.8,-8.8,0.118,0,0,-2,0.4
ENSMUSG00000022842,ECE2,endothelin converting enzyme 2,Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|cytoplasmic vesicle membrane|,proteolysis|metabolic process|peptide hormone processing|peptide hormone processing|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|catalytic activity|protein C-terminal carboxyl O-methyltransferase activity|metalloendopeptidase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|peptidase activity|metallopeptidase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|hydrolase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.7,3.39,10,0.6,5.76,0.7,8.79,8.79,0.118,0,0,0.2,1.5
ENSMUSG00000060860,UBE2S,ubiquitin-conjugating enzyme E2S,anaphase-promoting complex|,cell cycle|exit from mitosis|free ubiquitin chain polymerization|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|protein K29-linked ubiquitination|protein K27-linked ubiquitination|cell division|activation of anaphase-promoting complex activity|protein K63-linked ubiquitination|protein K11-linked ubiquitination|protein K6-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0.5,2.01,10,0.6,7.22,0.6,8.76,8.76,0.118,0,0,0.2,1.2
ENSMUSG00000069270,HIST1H2AC,"histone cluster 1, H2ac",nucleus|extracellular vesicular exosome|,biological_process|,enzyme binding|,6,0.8,8.5,6,-0.5,2.12,0.8,8.75,8.75,0.118,0,0,0.2,2
ENSMUSG00000022553,MAF1,MAF1 homolog (S. cerevisiae),intracellular|nucleus|nucleus|cytoplasm|cytosol|plasma membrane|axon|dendrite|inhibitory synapse|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription from RNA polymerase III promoter|",RNA polymerase III type 1 promoter DNA binding|RNA polymerase III type 2 promoter DNA binding|RNA polymerase III type 3 promoter DNA binding|,10,1.2,10.3,10,0.3,1.4,1.2,8.62,8.62,0.119,0,0,0.4,1.9
ENSMUSG00000041264,USPL1,ubiquitin specific peptidase like 1,extracellular space|nucleus|Cajal body|,proteolysis|cell proliferation|protein desumoylation|Cajal body organization|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|SUMO binding|SUMO-specific isopeptidase activity|,9,-0.5,2.02,10,-0.8,7.47,-0.7,8.59,-8.59,0.12,0,0,-1.6,-0.2
ENSMUSG00000056342,USP34,ubiquitin specific peptidase 34,cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|Wnt signaling pathway|protein deubiquitination|protein K48-linked deubiquitination|positive regulation of canonical Wnt signaling pathway|,cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,9,1.3,2.29,9,1.1,6.74,1.2,8.55,8.55,0.12,0,0,0.4,2
ENSMUSG00000037965,ZC3H7A,zinc finger CCCH type containing 7 A,cellular_component|,biological_process|,poly(A) RNA binding|metal ion binding|,10,-0.6,5.75,10,-0.4,3.76,-0.5,8.47,-8.47,0.121,0,0,-1.2,-0.2
ENSMUSG00000022828,GTF2E1,"general transcription factor II E, polypeptide 1 (alpha subunit)",nucleus|intermediate filament cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|",molecular_function|sequence-specific DNA binding|metal ion binding|,10,0.6,8.61,10,-1.2,7.27,0.6,8.4,8.4,0.122,0,0,-1.4,1.7
ENSMUSG00000024287,THOC1,THO complex 1,transcription export complex|THO complex|THO complex part of transcription export complex|nucleus|cytoplasm|intercellular bridge|,"regulation of DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|mRNA export from nucleus|transport|apoptotic process|apoptotic process|signal transduction|RNA splicing|replication fork processing|regulation of DNA-templated transcription, elongation|positive regulation of DNA-templated transcription, elongation|regulation of apoptotic process|viral mRNA export from host cell nucleus|negative regulation of isotype switching to IgA isotypes|mRNA transport|negative regulation of DNA damage checkpoint|",DNA binding|RNA binding|protein binding|,9,-1.2,3.6,9,0.8,9.53,0.7,8.28,8.28,0.123,0,0,0.1,1.8
ENSMUSG00000052752,TRAF7,TNF receptor-associated factor 7,ubiquitin ligase complex|cytoplasmic vesicle|,"activation of MAPKKK activity|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|protein ubiquitination|protein ubiquitination|positive regulation of MAPK cascade|positive regulation of apoptotic signaling pathway|","ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.6,7.82,10,0.3,2.02,0.5,8.21,8.21,0.124,0,0,0.2,1.4
ENSMUSG00000056055,SAG,"S-antigen, retina and pineal gland (arrestin)",photoreceptor outer segment|photoreceptor outer segment|photoreceptor inner segment|photoreceptor inner segment|,signal transduction|visual perception|response to stimulus|,opsin binding|spectrin binding|phosphoprotein binding|,10,0.7,7.47,10,0.4,1.15,0.6,8.16,8.16,0.124,0,0,0.2,1.4
ENSMUSG00000074627,MROH8,maestro heat-like repeat family member 8,cellular_component|,biological_process|,molecular_function|,10,0.9,10.8,10,-0.3,1.38,0.9,8.12,8.12,0.125,0,0,0.2,1.7
ENSMUSG00000027363,USP8,ubiquitin specific peptidase 8,acrosomal vesicle|intracellular|intracellular|nucleus|cytoplasm|endosome|early endosome|cytosol|cytosol|plasma membrane|membrane|extrinsic component of plasma membrane|midbody|midbody|extrinsic component of endosome membrane|,mitotic cytokinesis|proteolysis|ubiquitin-dependent protein catabolic process|endosome organization|endosome organization|cell cycle|Ras protein signal transduction|protein deubiquitination|protein deubiquitination|protein deubiquitination|protein K63-linked deubiquitination|protein K48-linked deubiquitination|,ubiquitin-specific protease activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|SH3 domain binding|ubiquitinyl hydrolase activity|,8,-1.6,6.73,7,-0.8,3.35,-1.4,8.05,-8.05,0.126,0,0,-2.6,-0.3
ENSMUSG00000033596,RFWD3,ring finger and WD repeat domain 3,nucleus|cytoplasm|site of double-strand break|,DNA repair|cellular response to DNA damage stimulus|response to ionizing radiation|protein ubiquitination|mitotic G1 DNA damage checkpoint|regulation of DNA damage checkpoint|,"p53 binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|MDM2/MDM4 family protein binding|",10,0.5,4.41,10,0.5,3.94,0.5,8.01,8.01,0.126,0,0,0.2,1.3
ENSMUSG00000003644,RPS6KA1,ribosomal protein S6 kinase polypeptide 1,nucleus|cytoplasm|spindle|ribosome|ribonucleoprotein complex|,"protein phosphorylation|phosphorylation|intracellular signal transduction|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hepatic stellate cell activation|","nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine/tyrosine kinase activity|ATP binding|transcription factor binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|",8,0.5,3.35,8,0.6,5.07,0.6,8,8,0.126,0,0,0.1,1.3
ENSMUSG00000037894,H2AFZ,"H2A histone family, member Z",nucleosome|nucleus|nucleus|nucleus|chromosome|nuclear euchromatin|nuclear heterochromatin|,multicellular organismal development|positive regulation of transcription from RNA polymerase II promoter|cellular response to estradiol stimulus|,RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|DNA binding|chromatin DNA binding|nucleosomal DNA binding|protein heterodimerization activity|,6,0.5,1.43,7,0.7,7.2,0.6,7.94,7.94,0.127,0,0,0.2,1.6
ENSMUSG00000072889,NFXL1,"nuclear transcription factor, X-box binding-like 1",membrane|,biological_process|,molecular_function|metal ion binding|,10,-1.1,7.02,10,-0.9,1.44,-1.1,7.89,-7.89,0.128,0,0,-1.9,-0.4
ENSMUSG00000031479,VPS36,vacuolar protein sorting 36 (yeast),intracellular|cell|nucleus|cytoplasm|lysosome|endosome|late endosome|membrane|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|protein transport|endosomal transport|",lipid binding|phosphatidylinositol-3-phosphate binding|ubiquitin binding|,9,-2,6.77,10,-0.7,5.96,-1.9,7.87,-7.87,0.128,0,0,-4,0.6
ENSMUSG00000006289,OSGEP,O-sialoglycoprotein endopeptidase,cellular_component|nucleus|cytoplasm|,tRNA processing|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|metal ion binding|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",9,-0.6,4.79,9,-1,4.03,-0.6,7.8,-7.8,0.129,0,0,-2,1
ENSMUSG00000029642,POLR1D,polymerase (RNA) I polypeptide D,nucleus|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase I complex|,"transcription, DNA-templated|",RNA polymerase I activity|RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|protein binding|protein dimerization activity|,8,0.6,3.24,7,-1,9.96,-1,7.69,-7.69,0.13,0,0,-2,0.5
ENSMUSG00000024142,MLST8,"MTOR associated protein, LST8 homolog (S. cerevisiae)",cytoplasm|cytosol|TORC1 complex|TORC2 complex|,positive regulation of actin filament polymerization|positive regulation of TOR signaling|regulation of Rac GTPase activity|regulation of actin cytoskeleton organization|positive regulation of peptidyl-tyrosine phosphorylation|,None,10,0.7,6.73,10,0.4,1.52,0.7,7.66,7.66,0.131,0,0,0.2,1.6
ENSMUSG00000023150,IVNS1ABP,influenza virus NS1A binding protein,nucleus|cytoplasm|cytoskeleton|,negative regulation of intrinsic apoptotic signaling pathway|,protein binding|,10,0.5,4.08,10,1.1,4.83,0.9,7.51,7.51,0.133,0,0,0.3,1.8
ENSMUSG00000014074,RNF168,ring finger protein 168,ubiquitin ligase complex|nucleus|mitochondrion|site of double-strand break|,DNA repair|double-strand break repair|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|response to ionizing radiation|protein ubiquitination|chromatin modification|histone H2A monoubiquitination|histone H2A-K13 ubiquitination|histone H2A-K15 ubiquitination|isotype switching|positive regulation of DNA repair|negative regulation of translational elongation|protein K63-linked ubiquitination|histone H2A K63-linked ubiquitination|,"chromatin binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|nucleosome binding|histone binding|ubiquitin binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|K63-linked polyubiquitin binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",7,0.6,1.31,7,1.1,7.24,0.7,7.47,7.47,0.134,0,0,0.2,1.8
ENSMUSG00000029203,UBE2K,ubiquitin-conjugating enzyme E2K,intracellular|cytoplasm|extracellular vesicular exosome|,protein ubiquitination|regulation of proteasomal ubiquitin-dependent protein catabolic process|regulation of proteasomal ubiquitin-dependent protein catabolic process|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|ubiquitin protein ligase binding|ubiquitin-ubiquitin ligase activity|,10,-0.8,5.86,10,-0.4,3.12,-0.7,7.46,-7.46,0.134,0,0,-1.5,-0.2
ENSMUSG00000048970,C1GALT1C1,C1GALT1-specific chaperone 1,membrane|integral component of membrane|extracellular vesicular exosome|,protein O-linked glycosylation|protein O-linked glycosylation|platelet activation|platelet morphogenesis|positive regulation of transferase activity|,molecular_function|,10,0.9,0.55,10,0.9,7.08,0.9,7.4,7.4,0.135,0,0,0.3,1.8
ENSMUSG00000041130,ZFP598,zinc finger protein 598,None,biological_process|,zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.7,6.19,10,-0.3,2.26,-0.6,7.37,-7.37,0.135,0,0,-1.3,-0.1
ENSMUSG00000064373,SEPP1,"selenoprotein P, plasma, 1",extracellular region|extracellular space|extracellular vesicular exosome|,selenium compound metabolic process|selenium compound metabolic process|brain development|locomotory behavior|post-embryonic development|sexual reproduction|growth|,selenium binding|,10,-1,9.55,10,0,0,-0.9,7.36,-7.36,0.136,0,0,-1.8,-0.3
ENSMUSG00000024597,SLC12A2,"solute carrier family 12, member 2",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|extracellular vesicular exosome|,transport|ion transport|potassium ion transport|sodium ion transport|chloride transport|hyperosmotic response|organic cation transport|ammonium transport|transepithelial chloride transport|multicellular organism growth|positive regulation of cell volume|detection of mechanical stimulus involved in sensory perception of sound|transmembrane transport|branching involved in mammary gland duct morphogenesis|mammary duct terminal end bud growth|transepithelial ammonium transport|ammonium transmembrane transport|chloride transmembrane transport|,transporter activity|protein binding|sodium:potassium:chloride symporter activity|ammonium transmembrane transporter activity|symporter activity|cation:chloride symporter activity|,10,-1.4,10.4,10,0.2,0.63,-1.4,7.35,-7.35,0.136,0,0,-2.8,-0.2
ENSMUSG00000027828,SSR3,"signal sequence receptor, gamma",endoplasmic reticulum|Sec61 translocon complex|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,cotranslational protein targeting to membrane|,None,10,-0.4,4.69,9,-0.4,2.9,-0.4,7.27,-7.27,0.137,0,0,-1.4,0
ENSMUSG00000020128,VPS54,vacuolar protein sorting 54 (yeast),GARP complex|Golgi apparatus|,"transport|protein transport|growth|retrograde transport, endosome to Golgi|homeostasis of number of cells within a tissue|musculoskeletal movement|neurofilament cytoskeleton organization|",None,10,-0.5,3.23,10,-0.6,4.33,-0.5,7.21,-7.21,0.138,0,0,-1.4,-0.1
ENSMUSG00000039633,LONRF1,LON peptidase N-terminal domain and ring finger 1,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.9,2.62,10,1.1,5.07,1,7.17,7.17,0.139,0,0,-0.4,2
ENSMUSG00000025903,LYPLA1,lysophospholipase 1,cytoplasm|mitochondrion|cytosol|extracellular vesicular exosome|,protein depalmitoylation|lipid metabolic process|fatty acid metabolic process|negative regulation of Golgi to plasma membrane protein transport|,"lysophospholipase activity|palmitoyl-(protein) hydrolase activity|CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0.6,3.81,10,0.5,3.71,0.6,7.14,7.14,0.139,0,0,0.1,1.4
ENSMUSG00000027395,POLR1B,polymerase (RNA) I polypeptide B,nucleus|nucleolus|nucleolus|DNA-directed RNA polymerase I complex|DNA-directed RNA polymerase I complex|cytoplasm|,"transcription, DNA-templated|embryo implantation|rRNA transcription|rRNA transcription|embryo development|nucleologenesis|",DNA binding|DNA-directed RNA polymerase activity|protein binding|transferase activity|nucleotidyltransferase activity|ribonucleoside binding|metal ion binding|,7,0.9,6.24,6,0.9,1.14,0.9,7.11,7.11,0.139,0,0,0.2,1.8
ENSMUSG00000019689,1110001J03RIK,RIKEN cDNA 1110001J03 gene,mitochondrion|,biological_process|,molecular_function|,9,-0.2,0.692,9,-0.6,7.74,-0.5,7.11,-7.11,0.139,0,0,-1.3,-0.1
ENSMUSG00000025492,IFITM3,interferon induced transmembrane protein 3,nucleus|cytoplasm|lysosome|endosome|endoplasmic reticulum|plasma membrane|cell surface|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|apical part of cell|extracellular vesicular exosome|,immune system process|negative regulation of cell proliferation|response to biotic stimulus|response to virus|response to virus|negative regulation of viral transcription|response to interferon-gamma|response to interferon-alpha|response to interferon-beta|negative regulation of viral genome replication|innate immune response|negative regulation of viral entry into host cell|negative regulation of viral entry into host cell|defense response to virus|defense response to virus|type I interferon signaling pathway|,None,10,-0.3,0.883,10,-0.5,6.56,-0.5,7.07,-7.07,0.14,0,0,-1.3,0
ENSMUSG00000084786,UBL5,ubiquitin-like 5,cytoplasm|,biological_process|,molecular_function|,9,-1.3,2.27,9,-1.3,5.09,-1.3,7.05,-7.05,0.141,0,0,-2,0.6
ENSMUSG00000022175,LRP10,low-density lipoprotein receptor-related protein 10,membrane|integral component of membrane|,lipid metabolic process|lipid transport|receptor-mediated endocytosis|inner ear development|,low-density lipoprotein receptor activity|,10,-1.2,3.37,10,-0.9,4.23,-1,7.02,-7.02,0.141,0,0,-1.9,-0.3
ENSMUSG00000028433,UBAP2,ubiquitin-associated protein 2,cellular_component|,biological_process|,poly(A) RNA binding|,10,-1.5,10,10,0,0,-1.4,6.97,-6.97,0.142,0,0,-2.8,-0.2
ENSMUSG00000028879,STX12,syntaxin 12,endosome|Golgi apparatus|membrane|integral component of membrane|BLOC-1 complex|SNARE complex|SNARE complex|membrane raft|phagocytic vesicle|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|synaptic vesicle exocytosis|vesicle-mediated transport|cholesterol efflux|protein stabilization|,SNARE binding|SNAP receptor activity|protein binding|,10,0.7,7.63,10,-1,3.53,0.6,6.95,6.95,0.142,0,0,-0.8,1.6
ENSMUSG00000022283,PABPC1,"poly(A) binding protein, cytoplasmic 1",nucleus|spliceosomal complex|cytoplasm|cytoplasmic stress granule|membrane|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|catalytic step 2 spliceosome|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|mRNA processing|RNA splicing|gene silencing by RNA|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|",nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|protein binding|protein C-terminus binding|poly(A) binding|poly(U) RNA binding|poly(A) RNA binding|,3,0.9,7.75,3,0.3,0.172,0.9,6.93,6.93,0.143,0,0,0.3,2
ENSMUSG00000025485,RIC8,resistance to inhibitors of cholinesterase 8 homolog (C. elegans),cytoplasm|cytosol|plasma membrane|membrane|,in utero embryonic development|vasculature development|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|gastrulation|regulation of G-protein coupled receptor protein signaling pathway|visual learning|response to light stimulus|cell migration involved in gastrulation|positive regulation of GTPase activity|cell-cell adhesion involved in gastrulation|basement membrane organization|,G-protein alpha-subunit binding|guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|,8,0.1,0.0445,9,1.2,8.91,1.2,6.92,6.92,0.143,0,0,0.3,2
ENSMUSG00000043557,MDGA1,MAM domain containing glycosylphosphatidylinositol anchor 1,extracellular space|plasma membrane|membrane|anchored component of membrane|membrane raft|anchored component of plasma membrane|,neuron migration|neuron migration|multicellular organismal development|nervous system development|cerebral cortex radially oriented cell migration|cell differentiation|,molecular_function|,10,0.7,6.03,10,-0.5,2.62,0.7,6.85,6.85,0.144,0,0,-0.3,1.7
ENSMUSG00000024922,OVOL1,OVO homolog-like 1 (Drosophila),nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|kidney development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cytoskeleton organization|spermatogenesis|mesoderm development|epidermis development|epidermal cell differentiation|skin development|germline cell cycle switching, mitotic to meiotic cell cycle|negative regulation of meiotic cell cycle phase transition|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.3,1.04,10,1.2,9.79,1.1,6.82,6.82,0.145,0,0,-0.2,2
ENSMUSG00000040560,WDR7,WD repeat domain 7,cellular_component|,hematopoietic progenitor cell differentiation|,molecular_function|,10,0.6,4.55,10,0.4,2.64,0.5,6.79,6.79,0.145,0,0,0.1,1.4
ENSMUSG00000017188,COA3,cytochrome C oxidase assembly factor 3,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|integral component of mitochondrial inner membrane|,mitochondrial respiratory chain complex IV assembly|positive regulation of mitochondrial translation|,molecular_function|,10,0.7,2.23,10,1.3,6.3,0.8,6.68,6.68,0.147,0,0,0.2,1.9
ENSMUSG00000074155,KLK5,kallikrein related-peptidase 5,epidermal lamellar body|,proteolysis|positive regulation of G-protein coupled receptor protein signaling pathway|,serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.6,2.68,10,-1.7,9.03,-1.6,6.63,-6.63,0.148,0,0,-3,-0.2
ENSMUSG00000027035,CERS6,ceramide synthase 6,nucleus|endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|sphingolipid biosynthetic process|ceramide biosynthetic process|,DNA binding|sphingosine N-acyltransferase activity|,10,-0.4,1.73,10,-0.7,5.71,-0.5,6.48,-6.48,0.151,0,0,-1.6,0.2
ENSMUSG00000025188,HPS1,Hermansky-Pudlak syndrome 1 homolog (human),cell|cytoplasmic membrane-bounded vesicle|BLOC-3 complex|,organelle organization|blood coagulation|melanocyte differentiation|positive regulation of natural killer cell activation|secretion of lysosomal enzymes|pigmentation|eye pigmentation|retina development in camera-type eye|,protein dimerization activity|,10,0.4,3.26,9,0.5,3.72,0.5,6.43,6.43,0.153,0,0,0.1,1.2
ENSMUSG00000046997,SPSB4,splA/ryanodine receptor domain and SOCS box containing 4,cellular_component|cytoplasm|,biological_process|intracellular signal transduction|,protein binding|,10,0.5,4.23,10,0.4,2.6,0.5,6.43,6.43,0.153,0,0,0.1,1.2
ENSMUSG00000014905,DNAJB9,"DnaJ (Hsp40) homolog, subfamily B, member 9",nucleolus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|extracellular vesicular exosome|,ER-associated ubiquitin-dependent protein catabolic process|ER-associated ubiquitin-dependent protein catabolic process|,protein binding|misfolded protein binding|,10,0.5,3.22,10,0.5,3.48,0.5,6.38,6.38,0.154,0,0,-0.1,1.3
ENSMUSG00000035086,BECN1,"beclin 1, autophagy related",nucleus|cytoplasm|cytoplasm|Golgi apparatus|trans-Golgi network|cytoskeleton|membrane|cytoplasmic membrane-bounded vesicle|dendrite|protein complex|phagocytic vesicle|,autophagic vacuole assembly|cytokinesis|autophagy|autophagy|autophagy|lysosome organization|cell cycle|negative regulation of cell proliferation|positive regulation of macroautophagy|neuron development|beta-amyloid metabolic process|regulation of catalytic activity|cell division|defense response to virus|response to other organism|negative regulation of cell death|,protein binding|,10,0.8,3.82,10,1,2.92,1,6.37,6.37,0.154,0,0,0.2,1.8
ENSMUSG00000039768,DNAJC11,"DnaJ (Hsp40) homolog, subfamily C, member 11",mitochondrion|mitochondrial inner membrane|extracellular vesicular exosome|,biological_process|,None,10,0.6,4.05,10,0.4,2.66,0.5,6.34,6.34,0.154,0,0,0.1,1.5
ENSMUSG00000034127,TSPAN8,tetraspanin 8,cellular_component|membrane|integral component of membrane|,negative regulation of blood coagulation|,molecular_function|,10,-1.4,8.44,10,-0.2,0.397,-0.3,6.34,-6.34,0.154,0,0,-2,-0.2
ENSMUSG00000038664,HERC1,hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1,cellular_component|,negative regulation of autophagy|cerebellar Purkinje cell differentiation|neuron projection development|neuromuscular process controlling balance|,molecular_function|ligase activity|,10,-0.2,1.57,10,-0.6,6.33,-0.4,6.32,-6.32,0.155,0,0,-1.3,-0.1
ENSMUSG00000029017,PMPCB,peptidase (mitochondrial processing) beta,mitochondrion|mitochondrion|mitochondrial inner membrane|,proteolysis|,catalytic activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,9,-1.2,9.2,8,0.4,2.16,-1.1,6.31,-6.31,0.155,0,0,-2,1.1
ENSMUSG00000058979,CECR5,"cat eye syndrome chromosome region, candidate 5",mitochondrion|,biological_process|,molecular_function|,10,-0.3,4.45,10,-1.3,4.24,-0.3,6.3,-6.3,0.155,0,0,-1.8,-0.1
ENSMUSG00000026926,PMPCA,peptidase (mitochondrial processing) alpha,extracellular space|mitochondrion|mitochondrion|,proteolysis|,catalytic activity|endopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,9,1.1,7.32,10,-0.6,3.95,1,6.26,6.26,0.156,0,0,-0.7,2
ENSMUSG00000038736,NUDCD1,NudC domain containing 1,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.5,3.25,9,1.1,4.14,0.5,6.17,6.17,0.158,0,0,0.1,1.8
ENSMUSG00000067276,CAPN6,calpain 6,intracellular|cytoplasm|cytoskeleton|microtubule|spindle microtubule|perinuclear region of cytoplasm|,microtubule bundle formation|proteolysis|regulation of cytoskeleton organization|,calcium-dependent cysteine-type endopeptidase activity|protein binding|microtubule binding|,10,0,0,10,1.2,9.23,1.2,6.15,6.15,0.159,0,0,0.3,2
ENSMUSG00000062963,UFC1,ubiquitin-fold modifier conjugating enzyme 1,extracellular vesicular exosome|,response to endoplasmic reticulum stress|protein ufmylation|,protein binding|UFM1 conjugating enzyme activity|,10,0.4,1.72,10,0.4,4.69,0.4,6.12,6.12,0.16,0,0,0,1.2
ENSMUSG00000008450,NUTF2,nuclear transport factor 2,intracellular|cell|extracellular vesicular exosome|,protein import into nucleus|protein export from nucleus|,protein transporter activity|,7,-0.7,2.03,7,-1.1,5.28,-1,6.11,-6.11,0.16,0,0,-2,0
ENSMUSG00000038301,SNX10,sorting nexin 10,nucleus|nucleus|cytoplasm|endosome|endoplasmic reticulum|endoplasmic reticulum|centrosome|cytoskeleton|membrane|extrinsic component of endosome membrane|,transport|intracellular protein transport|endosome organization|protein transport|cell projection organization|osteoclast differentiation|cilium assembly|protein localization to cilium|protein localization to centrosome|,1-phosphatidylinositol binding|lipid binding|phosphatidylinositol binding|ATPase binding|,10,-0.2,0.749,10,-1.7,8.95,-1.7,5.99,-5.99,0.163,0,0,-3,-0.2
ENSMUSG00000022024,SUGT1,"SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)",nucleus|cytoplasm|,biological_process|,molecular_function|,8,-1.3,8.14,8,-0.2,1.08,-1.3,5.95,-5.95,0.164,0,0,-2,-0.2
ENSMUSG00000031333,ABCB7,"ATP-binding cassette, sub-family B (MDR/TAP), member 7",mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|membrane|integral component of membrane|,ATP catabolic process|transport|cellular iron ion homeostasis|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,0.5,2.66,10,0.4,3.67,0.5,5.95,5.95,0.164,0,0,0.1,1.5
ENSMUSG00000040688,TBL3,transducin (beta)-like 3,nucleus|nucleolus|small-subunit processome|,rRNA processing|biological_process|,poly(A) RNA binding|,8,-0.9,3.78,8,1.1,8.26,1.1,5.94,5.94,0.164,0,0,-0.8,2
ENSMUSG00000079197,PSME2,"proteasome (prosome, macropain) activator subunit 2 (PA28 beta)",membrane|extracellular vesicular exosome|,positive regulation of endopeptidase activity|antigen processing and presentation of exogenous antigen|,protein binding|endopeptidase activator activity|,10,0.7,5.06,10,0.8,1.18,0.7,5.93,5.93,0.165,0,0,0.1,1.8
ENSMUSG00000024772,EHD1,EH-domain containing 1,endosome|early endosome|lipid particle|plasma membrane|endosome membrane|membrane|membrane|endocytic vesicle|platelet dense tubular network membrane|early endosome membrane|perinuclear region of cytoplasm|recycling endosome membrane|extracellular vesicular exosome|,intracellular protein transport|endocytosis|endocytosis|positive regulation of cholesterol storage|endosomal transport|neuron projection development|endocytic recycling|low-density lipoprotein particle clearance|cholesterol homeostasis|protein homooligomerization|positive regulation of myoblast fusion|cellular response to nerve growth factor stimulus|positive regulation of endocytic recycling|,nucleotide binding|GTPase activity|calcium ion binding|protein binding|ATP binding|GTP binding|Rab GTPase binding|metal ion binding|,10,0.9,5.42,10,0.3,1.89,0.7,5.91,5.91,0.165,0,0,0.1,1.7
ENSMUSG00000032060,CRYAB,"crystallin, alpha B",nucleus|cytoplasm|mitochondrion|Golgi apparatus|cytosol|plasma membrane|cell surface|microtubule cytoskeleton|Z disc|I band|actin filament bundle|contractile fiber|extracellular vesicular exosome|,response to hypoxia|lens development in camera-type eye|protein folding|tubulin complex assembly|muscle organ development|negative regulation of gene expression|regulation of cell death|negative regulation of cell growth|microtubule polymerization or depolymerization|negative regulation of intracellular transport|response to hydrogen peroxide|camera-type eye development|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|protein homooligomerization|stress-activated MAPK cascade|apoptotic process involved in morphogenesis|cellular response to gamma radiation|negative regulation of reactive oxygen species metabolic process|,structural constituent of eye lens|protein binding|microtubule binding|cytoskeletal protein binding|identical protein binding|protein homodimerization activity|metal ion binding|unfolded protein binding|,10,1,8.73,10,0,0,1,5.87,5.87,0.166,0,0,0.2,1.9
ENSMUSG00000018501,NCOR1,nuclear receptor co-repressor 1,histone deacetylase complex|nuclear chromatin|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|spindle microtubule|membrane|Sin3 complex|transcriptional repressor complex|transcriptional repressor complex|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|positive regulation of cell proliferation|negative regulation of gene expression|negative regulation of phosphatidylinositol 3-kinase signaling|chromatin modification|thalamus development|regulation of histone deacetylation|positive regulation of histone deacetylation|circadian regulation of gene expression|regulation of multicellular organism growth|cholesterol homeostasis|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of JNK cascade|regulation of catalytic activity|spindle assembly|definitive erythrocyte differentiation|regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter|regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region DNA binding|RNA polymerase II activating transcription factor binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|transcription corepressor activity|protein binding|protein domain specific binding|protein domain specific binding|estrogen receptor binding|histone deacetylase regulator activity|histone deacetylase regulator activity|nuclear hormone receptor binding|histone deacetylase binding|retinoic acid receptor binding|retinoic acid receptor binding|peroxisome proliferator activated receptor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|retinoid X receptor binding|retinoid X receptor binding|thyroid hormone receptor binding|thyroid hormone receptor binding|,10,-0.5,4.16,10,-0.3,2.39,-0.4,5.86,-5.86,0.166,0,0,-1.2,0
ENSMUSG00000024792,ZFPL1,zinc finger like protein 1,Golgi apparatus|membrane|integral component of membrane|,transport|biological_process|vesicle-mediated transport|,protein binding|zinc ion binding|metal ion binding|,9,0.8,8.41,9,-0.9,0.779,0.7,5.83,5.83,0.167,0,0,-0.3,2
ENSMUSG00000050445,CYP8B1,"cytochrome P450, family 8, subfamily b, polypeptide 1",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|sterol 12-alpha-hydroxylase activity|sterol 12-alpha-hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity|metal ion binding|",10,0.1,0.0509,10,1.2,8.17,0.8,5.81,5.81,0.168,0,0,0,2
ENSMUSG00000025171,UBTD1,ubiquitin domain containing 1,cellular_component|,biological_process|,molecular_function|,10,1.6,9.13,10,0,0,1.6,5.76,5.76,0.169,0,0,-0.3,3
ENSMUSG00000028958,TMUB1,transmembrane and ubiquitin-like domain containing 1,nucleus|cytoplasm|membrane|integral component of membrane|,None,None,10,-0.6,1.89,10,-0.5,4.19,-0.5,5.76,-5.76,0.169,0,0,-1.4,0.2
ENSMUSG00000024121,ATP6V0C,"ATPase, H+ transporting, lysosomal V0 subunit C","lysosome|lysosomal membrane|vacuole|Golgi apparatus|membrane|integral component of membrane|vacuolar proton-transporting V-type ATPase complex|proton-transporting two-sector ATPase complex, proton-transporting domain|proton-transporting V-type ATPase, V0 domain|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|vacuolar acidification|lysosomal lumen acidification|ATP hydrolysis coupled proton transport|proton transport|positive regulation of Wnt signaling pathway|hydrogen ion transmembrane transport|,"protein binding|hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrogen ion transmembrane transporter activity|ubiquitin protein ligase binding|",8,1,8.57,8,-0.3,1.82,1,5.76,5.76,0.169,0,0,-0.7,2
ENSMUSG00000048429,1810026J23RIK,RIKEN cDNA 1810026J23 gene,cellular_component|,biological_process|,molecular_function|,7,1,4.94,6,0.8,1.07,0.9,5.7,5.7,0.171,0,0,-0.1,2
ENSMUSG00000015714,CERS2,ceramide synthase 2,nucleus|endoplasmic reticulum|membrane|membrane|integral component of membrane|nuclear membrane|,lipid metabolic process|sphingolipid biosynthetic process|ceramide biosynthetic process|,DNA binding|sphingosine N-acyltransferase activity|,10,0.4,2.25,10,0.5,3.75,0.4,5.67,5.67,0.171,0,0,0,1.5
ENSMUSG00000032558,NPHP3,nephronophthisis 3 (adolescent),cilium|cell projection|primary cilium|,kidney development|heart looping|atrial septum development|lipid metabolic process|establishment or maintenance of cell polarity|determination of left/right symmetry|determination of left/right symmetry|Wnt signaling pathway|extracellular matrix organization|lung development|regulation of cAMP metabolic process|determination of pancreatic left/right asymmetry|photoreceptor cell maintenance|maintenance of organ identity|maintenance of organ identity|convergent extension involved in gastrulation|cilium morphogenesis|kidney morphogenesis|kidney morphogenesis|determination of intestine left/right asymmetry|determination of stomach left/right asymmetry|determination of liver left/right asymmetry|ureter development|negative regulation of canonical Wnt signaling pathway|,molecular_function|,10,-1.3,8.82,10,0,0,-1.3,5.54,-5.54,0.175,0,0,-2,-0.2
ENSMUSG00000079442,ST6GALNAC4,"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|,"sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity|",10,-0.2,0.402,10,0.7,5.88,0.8,5.5,5.5,0.177,0,0,0.1,1.8
ENSMUSG00000026020,NOP58,NOP58 ribonucleoprotein,nucleus|nucleolus|nucleolus|small nucleolar ribonucleoprotein complex|cytoplasm|Cajal body|membrane|ribonucleoprotein complex|pre-snoRNP complex|,snRNP protein import into nucleus|ribosome biogenesis|,snoRNA binding|snoRNP binding|poly(A) RNA binding|,7,0.3,1.38,7,0.6,4.86,0.5,5.5,5.5,0.177,0,0,-0.1,1.6
ENSMUSG00000029104,HTT,huntingtin,intracellular|cell|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|late endosome|autophagic vacuole|endoplasmic reticulum|Golgi apparatus|cytosol|postsynaptic density|cytoplasmic membrane-bounded vesicle|inclusion body|clathrin-coated vesicle|axon|axon|dendrite|cytoplasmic vesicle membrane|neuronal cell body|protein complex|neuronal ribonucleoprotein granule|,"urea cycle|citrulline metabolic process|establishment of mitotic spindle orientation|protein import into nucleus|mitochondrial transport|ER to Golgi vesicle-mediated transport|retrograde vesicle-mediated transport, Golgi to ER|apoptotic process|mitochondrion organization|endoplasmic reticulum organization|Golgi organization|dopamine receptor signaling pathway|spermatogenesis|gastrulation|central nervous system development|brain development|cell aging|learning or memory|learning|grooming behavior|locomotory behavior|axon cargo transport|associative learning|determination of adult lifespan|visual learning|anatomical structure morphogenesis|embryo development|anterior/posterior pattern specification|endosomal transport|lactate biosynthetic process from pyruvate|quinolinate biosynthetic process|striatum development|olfactory lobe development|neural plate formation|neurogenesis|peptide hormone secretion|insulin secretion|regulation of protein phosphatase type 2A activity|social behavior|hormone metabolic process|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|regulation of mitochondrial membrane permeability|vesicle transport along microtubule|vesicle transport along microtubule|regulation of synaptic plasticity|paraxial mesoderm formation|neuron development|mRNA transport|neuron apoptotic process|response to calcium ion|regulation of mitochondrial membrane potential|L-glutamate import|iron ion homeostasis|negative regulation of neuron death|negative regulation of cysteine-type endopeptidase activity|negative regulation of extrinsic apoptotic signaling pathway|",p53 binding|receptor binding|protein binding|transcription factor binding|dynactin binding|identical protein binding|dynein intermediate chain binding|beta-tubulin binding|diazepam binding|,9,0.7,6.45,10,0.2,0.391,0.7,5.44,5.44,0.178,0,0,0,1.7
ENSMUSG00000038784,CNOT4,"CCR4-NOT transcription complex, subunit 4",nucleus|cytoplasm|CCR4-NOT complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein autoubiquitination|","nucleotide binding|nucleic acid binding|RNA binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.8,5.86,10,0,0,0.9,5.43,5.43,0.178,0,0,0.1,1.9
ENSMUSG00000047866,LONP2,"lon peptidase 2, peroxisomal",nucleus|cytoplasm|peroxisome|peroxisomal matrix|peroxisomal matrix|membrane|,ATP catabolic process|proteolysis|misfolded or incompletely synthesized protein catabolic process|protein targeting to peroxisome|protein targeting to peroxisome|protein processing|protein processing|protein catabolic process|regulation of fatty acid beta-oxidation|,nucleotide binding|protease binding|ATP-dependent peptidase activity|serine-type endopeptidase activity|receptor binding|protein binding|ATP binding|peptidase activity|serine-type peptidase activity|hydrolase activity|enzyme binding|,10,0,0,10,0.9,7.65,0.8,5.43,5.43,0.178,0,0,0.1,1.9
ENSMUSG00000026353,UBXN4,UBX domain protein 4,nucleus|cytoplasm|endoplasmic reticulum|membrane|,response to unfolded protein|biological_process|,molecular_function|,10,-2,8.89,10,0,0,-2,5.43,-5.43,0.178,0,0,-4,-0.2
ENSMUSG00000057788,DDX49,DEAD (Asp-Glu-Ala-Asp) box polypeptide 49,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,6,0.8,2.98,6,0.8,2.75,0.8,5.43,5.43,0.178,0,0,0.1,1.9
ENSMUSG00000039233,TBCE,tubulin-specific chaperone E,cytoplasm|cytoskeleton|,microtubule cytoskeleton organization|protein folding|tubulin complex assembly|post-chaperonin tubulin folding pathway|axonogenesis|adult locomotory behavior|post-embryonic development|muscle atrophy|developmental growth|peripheral nervous system neuron axonogenesis|,unfolded protein binding|,9,-1,5.16,9,0.5,4.79,0.5,5.42,5.42,0.179,0,0,-1.6,1.5
ENSMUSG00000040767,SNRNP25,small nuclear ribonucleoprotein 25 (U11/U12),nucleus|nucleus|spliceosomal complex|U12-type spliceosomal complex|cytoplasm|intercellular bridge|,mRNA processing|biological_process|RNA splicing|,molecular_function|,8,1,1.79,9,1,3.91,1,5.42,5.42,0.179,0,0,-0.3,2
ENSMUSG00000001098,KCTD10,potassium channel tetramerisation domain containing 10,nucleus|cytoplasm|TCTN-B9D complex|TCTN-B9D complex|,biological_process|protein homooligomerization|,protein binding|,10,0.4,3.13,10,0.5,2.57,0.4,5.33,5.33,0.182,0,0,-0.1,1.2
ENSMUSG00000032353,TMED3,transmembrane emp24 domain containing 3,endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|integral component of membrane|COPI vesicle coat|cytoplasmic vesicle|,transport|biological_process|protein transport|,molecular_function|,10,-0.5,1.79,10,-0.7,3.96,-0.5,5.32,-5.32,0.182,0,0,-1.7,0.4
ENSMUSG00000045210,VCPIP1,valosin containing protein (p97)/p47 complex interacting protein 1,cytoplasm|endoplasmic reticulum|Golgi apparatus|,proteolysis|Golgi organization|mitotic nuclear division|endoplasmic reticulum membrane fusion|protein ubiquitination|protein K11-linked deubiquitination|protein K48-linked deubiquitination|Golgi reassembly|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.4,1.76,10,0.5,3.88,0.5,5.32,5.32,0.182,0,0,0,1.2
ENSMUSG00000025371,CHMP6,charged multivesicular body protein 6,endosome|membrane|membrane|extracellular vesicular exosome|,transport|protein transport|,protein N-terminus binding|,9,-0.7,7.62,10,0,0,-0.7,5.26,-5.26,0.184,0,0,-1.6,0
ENSMUSG00000021814,ANXA7,annexin A7,nucleus|nucleus|nuclear envelope|endoplasmic reticulum membrane|cytosol|plasma membrane|membrane|vesicle|chromaffin granule membrane|extracellular vesicular exosome|,cellular calcium ion homeostasis|autophagy|hemostasis|cell proliferation|regulation of cell shape|response to salt stress|cellular water homeostasis|negative regulation of gene expression|response to organic cyclic compound|response to calcium ion|membrane fusion|,integrin binding|calcium ion binding|protein binding|calcium-dependent phospholipid binding|poly(A) RNA binding|calcium-dependent protein binding|,10,-0.4,1.68,10,-1.2,5.09,-0.3,5.23,-5.23,0.185,0,0,-1.9,-0.1
ENSMUSG00000040350,TRIM7,tripartite motif-containing 7,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|,biological_process|,zinc ion binding|metal ion binding|,9,1.1,1.87,9,0.6,3.96,0.7,5.23,5.23,0.185,0,0,0.1,1.8
ENSMUSG00000041168,LONP1,"lon peptidase 1, mitochondrial",cytoplasm|mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial matrix|membrane|mitochondrial nucleoid|,ATP catabolic process|ATP catabolic process|proteolysis|proteolysis|misfolded or incompletely synthesized protein catabolic process|mitochondrion organization|mitochondrion organization|protein catabolic process|cellular response to oxidative stress|cellular protein complex assembly|chaperone-mediated protein complex assembly|protein homooligomerization|proteolysis involved in cellular protein catabolic process|oxidation-dependent protein catabolic process|,nucleotide binding|DNA binding|single-stranded DNA binding|single-stranded RNA binding|ATP-dependent peptidase activity|ATP-dependent peptidase activity|serine-type endopeptidase activity|ATP binding|peptidase activity|serine-type peptidase activity|hydrolase activity|ATPase activity|ADP binding|sequence-specific DNA binding|G-quadruplex DNA binding|DNA polymerase binding|mitochondrial light strand promoter anti-sense binding|mitochondrial light strand promoter anti-sense binding|,10,-1.1,6.05,9,0.1,0.0247,-0.9,5.19,-5.19,0.186,0,0,-2,0.4
ENSMUSG00000063172,HSPB11,"heat shock protein family B (small), member 11",intracellular|cell|centrosome|cilium|cilium|intraciliary transport particle B|intraciliary transport particle B|cell projection|extracellular vesicular exosome|,skeletal system development|transport|response to stress|cell adhesion|smoothened signaling pathway|heart development|protein transport|lung development|intraciliary transport|left/right axis specification|,molecular_function|metal ion binding|,8,-0.3,2.17,8,1.3,8.04,1.2,5.19,5.19,0.186,0,0,0,2
ENSMUSG00000035325,SEC31A,Sec31 homolog A (S. cerevisiae),cytoplasm|endosome|endoplasmic reticulum|membrane|vesicle coat|ER to Golgi transport vesicle|ER to Golgi transport vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|endoplasmic reticulum exit site|,transport|protein transport|vesicle-mediated transport|response to calcium ion|,calcium-dependent protein binding|,10,-1,7.04,9,0.6,5.15,-0.9,5.18,-5.18,0.187,0,0,-2,1.1
ENSMUSG00000005682,PAN2,PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae),cytoplasmic mRNA processing body|nucleus|cytoplasm|PAN complex|,"nuclear-transcribed mRNA poly(A) tail shortening|nuclear-transcribed mRNA catabolic process, exonucleolytic|mRNA processing|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|nucleic acid binding|nuclease activity|exonuclease activity|poly(A)-specific ribonuclease activity|protein binding|hydrolase activity|,10,-0.3,2.74,10,-0.6,3.73,-0.4,5.17,-5.17,0.187,0,0,-1.3,0.1
ENSMUSG00000043998,MGAT2,mannoside acetylglucosaminyltransferase 2,Golgi apparatus|Golgi stack|membrane|membrane|integral component of membrane|,protein N-linked glycosylation|oligosaccharide biosynthetic process|protein N-linked glycosylation via asparagine|,"alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity|alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|carbohydrate binding|",10,0.7,5.22,10,0.3,0.566,0.7,5.14,5.14,0.188,0,0,0.1,1.7
ENSMUSG00000036676,TMTC3,transmembrane and tetratricopeptide repeat containing 3,cellular_component|membrane|integral component of membrane|,post-embryonic development|regulation of gene expression|cell differentiation|lung development|lung alveolus development|muscle fiber development|bud outgrowth involved in lung branching|,molecular_function|,10,-0.7,4.31,9,-1.1,2.2,-0.8,5.11,-5.11,0.189,0,0,-2,0.3
ENSMUSG00000026166,CCL20,chemokine (C-C motif) ligand 20,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|positive regulation of interleukin-1 alpha biosynthetic process|positive regulation of nitric-oxide synthase biosynthetic process|cell chemotaxis|positive regulation of T cell migration|,cytokine activity|protein binding|chemokine activity|,9,1.2,5.7,9,0.3,0.847,0.7,5.09,5.09,0.19,0,0,0,2
ENSMUSG00000022436,SH3BP1,SH3-domain binding protein 1,intracellular|cytoplasm|,signal transduction|,GTPase activator activity|SH3 domain binding|,10,0.8,6.64,8,0.1,0.251,0.4,5.09,5.09,0.19,0,0,0,1.7
ENSMUSG00000046230,VPS13A,vacuolar protein sorting 13A (yeast),dense core granule|,transport|nervous system development|locomotory behavior|protein transport|social behavior|,molecular_function|,10,1.2,2.04,10,-1.2,7.98,-1.2,5.08,-5.08,0.19,0,0,-2,1
ENSMUSG00000005198,POLR2A,polymerase (RNA) II (DNA directed) polypeptide A,"nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II activity|DNA binding|DNA-directed RNA polymerase activity|protein binding|transferase activity|nucleotidyltransferase activity|ubiquitin protein ligase binding|poly(A) RNA binding|metal ion binding|,8,0.4,1.46,9,-0.7,5.26,-0.7,5.06,-5.06,0.191,0,0,-1.8,0.4
ENSMUSG00000031358,MSL3,male-specific lethal 3 homolog (Drosophila),nucleus|MSL complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H4-K16 acetylation|",DNA binding|methylated histone binding|,10,-0.2,1.85,10,-0.4,3.48,-0.3,4.95,-4.95,0.194,0,0,-1.1,0.2
ENSMUSG00000025217,BTRC,beta-transducin repeat containing protein,nucleus|cytoplasm|SCF ubiquitin ligase complex|,"protein polyubiquitination|protein dephosphorylation|ubiquitin-dependent protein catabolic process|Wnt signaling pathway|protein ubiquitination|protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|protein destabilization|mammary gland epithelial cell proliferation|regulation of circadian rhythm|positive regulation of circadian rhythm|regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of proteolysis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|rhythmic process|regulation of cell cycle|branching involved in mammary gland duct morphogenesis|regulation of proteasomal protein catabolic process|cellular response to organic cyclic compound|",ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|beta-catenin binding|protein phosphorylated amino acid binding|protein dimerization activity|,10,-0.1,0.12,10,0.5,5.74,0.4,4.93,4.93,0.195,0,0,-0.1,1.4
ENSMUSG00000012117,DHDDS,dehydrodolichyl diphosphate synthase,cellular_component|endoplasmic reticulum|membrane|,biological_process|,"prenyltransferase activity|protein geranylgeranyltransferase activity|protein prenyltransferase activity|4-hydroxybenzoate octaprenyltransferase activity|protoheme IX farnesyltransferase activity|transferase activity|transferase activity, transferring alkyl or aryl (other than methyl) groups|(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity|cadaverine aminopropyltransferase activity|agmatine aminopropyltransferase activity|1,4-dihydroxy-2-naphthoate octaprenyltransferase activity|trans-pentaprenyltranstransferase activity|ATP dimethylallyltransferase activity|ADP dimethylallyltransferase activity|",9,0.4,0.971,8,1,5.42,0.6,4.91,4.91,0.196,0,0,-1,2
ENSMUSG00000074115,SAA1,serum amyloid A 1,extracellular region|extracellular space|high-density lipoprotein particle|extracellular vesicular exosome|,acute-phase response|cholesterol metabolic process|,G-protein coupled receptor binding|protein binding|heparin binding|,10,0.6,6.14,10,0.1,0.347,0.6,4.88,4.88,0.197,0,0,0,1.4
ENSMUSG00000037761,ACTR5,ARP5 actin-related protein 5,nucleus|cytoplasm|Ino80 complex|,"DNA repair|double-strand break repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|UV-damage excision repair|",molecular_function|,10,0.5,5.78,10,-0.1,0.0372,0.5,4.87,4.87,0.197,0,0,-0.5,1.6
ENSMUSG00000004937,SGTA,"small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha",cytoplasm|,biological_process|,protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,-0.5,6.79,-0.4,4.85,-4.85,0.198,0,0,-1.3,0.3
ENSMUSG00000022360,ATAD2,"ATPase family, AAA domain containing 2",nucleus|extracellular vesicular exosome|,"ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",nucleotide binding|protein binding|ATP binding|hydrolase activity|ATPase activity|,9,0.5,1.71,9,1,3.74,0.9,4.82,4.82,0.199,0,0,0.1,2
ENSMUSG00000039100,6-Mar,membrane-associated ring finger (C3HC4) 6,endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,protein K48-linked ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|enzyme binding|ubiquitin conjugating enzyme binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.9,4.94,10,0.3,1.42,0.4,4.78,4.78,0.201,0,0,0.1,1.8
ENSMUSG00000062210,TNFAIP8,"tumor necrosis factor, alpha-induced protein 8",cytoplasm|,apoptotic process|interleukin-1 beta production|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|defense response to Gram-positive bacterium|,cysteine-type endopeptidase inhibitor activity involved in apoptotic process|,10,0.4,1.45,10,1.3,5.89,0.5,4.74,4.74,0.202,0,0,0.1,2
ENSMUSG00000013033,LPHN1,latrophilin 1,plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|axon|growth cone|presynaptic membrane|cell projection|neuron projection|synapse|,heterophilic cell-cell adhesion|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|calcium-mediated signaling using intracellular calcium source|positive regulation of synapse maturation|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|toxic substance binding|latrotoxin receptor activity|carbohydrate binding|cell adhesion molecule binding|,10,-2,7.92,10,0,0,-2,4.72,-4.72,0.203,0,0,-4,-0.2
ENSMUSG00000018733,PEX12,peroxisomal biogenesis factor 12,peroxisome|peroxisomal membrane|integral component of peroxisomal membrane|membrane|integral component of membrane|,protein targeting to peroxisome|transport|peroxisome organization|protein transport|protein import into peroxisome matrix|,protein C-terminus binding|zinc ion binding|metal ion binding|,10,-1,1.59,10,0.4,4.49,0.3,4.72,4.72,0.203,0,0,-1.2,1.3
ENSMUSG00000018930,CCL4,chemokine (C-C motif) ligand 4,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|response to toxic substance|leukocyte chemotaxis|positive regulation of tumor necrosis factor production|positive regulation of vascular permeability|negative regulation by host of viral transcription|positive regulation of calcium-mediated signaling|positive regulation of calcium ion transport|positive regulation of natural killer cell chemotaxis|,cytokine activity|protein binding|chemokine activity|CCR1 chemokine receptor binding|CCR5 chemokine receptor binding|identical protein binding|,10,0.5,2.93,10,0.4,2.05,0.5,4.7,4.7,0.204,0,0,0,1.6
ENSMUSG00000019832,RAB32,"RAB32, member RAS oncogene family",mitochondrion|early endosome|membrane|cytoplasmic vesicle|melanosome|phagocytic vesicle|,small GTPase mediated signal transduction|protein transport|antigen processing and presentation|melanosome organization|endosome to melanosome transport|phagosome maturation|,nucleotide binding|GTP binding|GTP-dependent protein binding|protein complex binding|AP-1 adaptor complex binding|AP-3 adaptor complex binding|,10,0.4,0.638,10,-1.2,7.89,-1.2,4.64,-4.64,0.206,0,0,-2,0.1
ENSMUSG00000038991,TXNDC5,thioredoxin domain containing 5,endoplasmic reticulum|endoplasmic reticulum lumen|extracellular vesicular exosome|,protein folding|response to endoplasmic reticulum stress|apoptotic cell clearance|cell redox homeostasis|,protein disulfide isomerase activity|isomerase activity|,9,-0.7,4.13,9,0.9,6.25,0.9,4.63,4.63,0.206,0,0,-1,1.9
ENSMUSG00000020124,USP15,ubiquitin specific peptidase 15,nucleus|cytoplasm|,proteolysis|ubiquitin-dependent protein catabolic process|transforming growth factor beta receptor signaling pathway|protein deubiquitination|BMP signaling pathway|monoubiquitinated protein deubiquitination|pathway-restricted SMAD protein phosphorylation|,catalytic activity|cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|ubiquitin-specific protease activity|transforming growth factor beta receptor binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|identical protein binding|SMAD binding|,10,-0.3,1.85,10,-0.4,3.16,-0.3,4.63,-4.63,0.206,0,0,-1.3,0.6
ENSMUSG00000006920,EZH1,enhancer of zeste homolog 1 (Drosophila),nucleus|nucleus|ESC/E(Z) complex|ESC/E(Z) complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|peptidyl-lysine methylation|methylation|histone H3-K27 methylation|",chromatin binding|protein binding|methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H3-K27 specific)|,10,0.1,0.354,10,1,5.67,0.7,4.61,4.61,0.207,0,0,0.1,1.9
ENSMUSG00000004264,PHB2,prohibitin 2,nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|nuclear matrix|protein complex|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of intracellular estrogen receptor signaling pathway|negative regulation of intracellular estrogen receptor signaling pathway|negative regulation of mammary gland epithelial cell proliferation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|mammary gland branching involved in thelarche|mammary gland alveolus development|regulation of branching involved in mammary gland duct morphogenesis|",protein binding|,7,-0.3,1.9,6,0.6,5.28,0.6,4.6,4.6,0.207,0,0,-0.7,1.8
ENSMUSG00000030407,QPCTL,glutaminyl-peptide cyclotransferase-like,Golgi apparatus|membrane|membrane|integral component of membrane|,"peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase|","zinc ion binding|glutaminyl-peptide cyclotransferase activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,0.7,3.57,9,0.3,1.78,0.4,4.56,4.56,0.209,0,0,0,1.6
ENSMUSG00000033228,SCAF11,SR-related CTD-associated factor 11,nucleus|,"spliceosomal complex assembly|RNA splicing, via transesterification reactions|RNA splicing|",poly(A) RNA binding|metal ion binding|,10,1.1,2.58,10,0.3,2.69,0.5,4.54,4.54,0.21,0,0,0,1.7
ENSMUSG00000034000,NEU4,sialidase 4,mitochondrion|membrane|organelle inner membrane|,carbohydrate metabolic process|glycoprotein catabolic process|lipid metabolic process|ganglioside catabolic process|metabolic process|oligosaccharide catabolic process|lipid catabolic process|,"exo-alpha-sialidase activity|exo-alpha-sialidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|exo-alpha-(2->3)-sialidase activity|exo-alpha-(2->6)-sialidase activity|exo-alpha-(2->8)-sialidase activity|",10,1.1,2.04,10,1,2.78,1,4.52,4.52,0.211,0,0,-0.3,2
ENSMUSG00000036391,SEC24A,"Sec24 related gene family, member A (S. cerevisiae)",cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|COPII vesicle coat|,transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|regulation of low-density lipoprotein particle receptor biosynthetic process|positive regulation of protein secretion|positive regulation of cholesterol homeostasis|,molecular_function|zinc ion binding|,10,-0.3,0.544,10,-0.7,5.02,-0.6,4.51,-4.51,0.211,0,0,-1.7,0.1
ENSMUSG00000067860,ZIC3,zinc finger protein of the cerebellum 3,nucleus|cytoplasm|,"heart looping|heart looping|heart looping|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|determination of left/right symmetry|determination of left/right symmetry|determination of left/right symmetry|pattern specification process|nervous system development|anterior/posterior pattern specification|cell differentiation|lung development|determination of pancreatic left/right asymmetry|determination of left/right asymmetry in nervous system|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|determination of digestive tract left/right asymmetry|determination of liver left/right asymmetry|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|metal ion binding|,10,-1.4,6.8,10,-0.3,0.671,-0.3,4.44,-4.44,0.215,0,0,-2,-0.1
ENSMUSG00000050565,TOR1AIP2,torsin A interacting protein 2,nucleus|endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|,endoplasmic reticulum organization|positive regulation of ATPase activity|,ATPase activator activity|protein binding|ATPase binding|,10,-0.5,1.62,10,-0.9,3.79,-0.8,4.43,-4.43,0.215,0,0,-1.9,0.1
ENSMUSG00000026705,KLHL20,kelch-like 20,nucleus|cytoplasm|Golgi apparatus|trans-Golgi network|PML body|Cul3-RING ubiquitin ligase complex|cell projection|,transport|Golgi to endosome transport|protein transport|protein ubiquitination|negative regulation of apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|protein K33-linked ubiquitination|,actin binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|interferon-gamma binding|,10,-0.6,3.66,9,-0.3,1.67,-0.4,4.42,-4.42,0.216,0,0,-1.5,1.2
ENSMUSG00000059187,FAM19A1,"family with sequence similarity 19, member A1",extracellular region|endoplasmic reticulum|,biological_process|,molecular_function|,10,0.3,2.21,10,1,4.01,0.5,4.42,4.42,0.216,0,0,0,1.7
ENSMUSG00000039703,NPLOC4,nuclear protein localization 4 homolog (S. cerevisiae),nucleus|cytoplasm|endoplasmic reticulum|cytosol|Cdc48p-Npl4p-Ufd1p AAA ATPase complex|,Golgi organization|membrane fusion|,zinc ion binding|ubiquitin protein ligase binding|protein complex binding|ubiquitin binding|metal ion binding|,9,0.8,3.74,8,-0.8,2.82,0.9,4.34,4.34,0.219,0,0,-1,2
ENSMUSG00000025034,TRIM8,tripartite motif-containing 8,nucleus|nucleus|cytoplasm|PML body|intracellular membrane-bounded organelle|,protein ubiquitination|negative regulation of viral transcription|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|innate immune response|negative regulation of viral entry into host cell|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|negative regulation of viral release from host cell|negative regulation of viral release from host cell|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|identical protein binding|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,0.825,9,0.6,4.19,0.4,4.27,4.27,0.222,0,0,-0.3,1.4
ENSMUSG00000026553,COPA,coatomer protein complex subunit alpha,extracellular region|extracellular space|cytoplasm|Golgi apparatus|membrane|membrane|membrane coat|COPI vesicle coat|cytoplasmic vesicle|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|pancreatic juice secretion|,hormone activity|structural molecule activity|,8,-0.4,3.66,9,-0.9,1.38,-0.5,4.26,-4.26,0.222,0,0,-1.8,0.8
ENSMUSG00000070407,HS3ST3B1,heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1,Golgi apparatus|integral component of plasma membrane|membrane|integral component of membrane|,protein sulfation|,sulfotransferase activity|[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity|transferase activity|[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity|,10,0.8,3.85,10,0.3,1.16,0.7,4.26,4.26,0.222,0,0,0,1.9
ENSMUSG00000038671,ARFRP1,ADP-ribosylation factor related protein 1,intracellular|Golgi apparatus|trans-Golgi network|membrane|,"GTP catabolic process|small GTPase mediated signal transduction|gastrulation|protein localization to Golgi apparatus|retrograde transport, endosome to Golgi|Golgi to plasma membrane protein transport|",nucleotide binding|GTPase activity|GTP binding|,10,1.1,6.96,10,-0.3,0.738,1.1,4.24,4.24,0.223,0,0,-1.1,2
ENSMUSG00000079057,CYP4V3,"cytochrome P450, family 4, subfamily v, polypeptide 3",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,fatty acid omega-oxidation|oxidation-reduction process|,"monooxygenase activity|iron ion binding|3-(3-hydroxyphenyl)propionate hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|4-chlorobenzaldehyde oxidase activity|3,5-xylenol methylhydroxylase activity|phenylacetate hydroxylase activity|4-nitrophenol 4-monooxygenase activity|dimethyl sulfide monooxygenase activity|alpha-pinene monooxygenase [NADH] activity|phenanthrene 9,10-monooxygenase activity|1-hydroxy-2-naphthoate hydroxylase activity|toluene 4-monooxygenase activity|xylene monooxygenase activity|dibenzothiophene monooxygenase activity|6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|chlorophenol 4-monooxygenase activity|carbon disulfide oxygenase activity|toluene 2-monooxygenase activity|1-hydroxy-2-oxolimonene 1,2-monooxygenase activity|phenanthrene 1,2-monooxygenase activity|tetrahydrofuran hydroxylase activity|styrene monooxygenase activity|toluene-4-sulfonate monooxygenase activity|toluene-sulfonate methyl-monooxygenase activity|3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|2-hydroxy-phenylacetate hydroxylase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity|phenanthrene 3,4-monooxygenase activity|toluene 3-monooxygenase activity|4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity|limonene monooxygenase activity|heme binding|2-methylnaphthalene hydroxylase activity|1-methylnaphthalene hydroxylase activity|bisphenol A hydroxylase A activity|salicylate 5-hydroxylase activity|isobutylamine N-hydroxylase activity|branched-chain dodecylbenzene sulfonate monooxygenase activity|3-HSA hydroxylase activity|4-hydroxypyridine-3-hydroxylase activity|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity|6-hydroxynicotinate 3-monooxygenase activity|metal ion binding|tocotrienol omega-hydroxylase activity|thalianol hydroxylase activity|",10,0.7,3.51,10,0.4,1.75,0.6,4.19,4.19,0.226,0,0,-0.4,1.7
ENSMUSG00000020231,DIP2A,DIP2 disco-interacting protein 2 homolog A (Drosophila),nucleus|cell surface|,multicellular organismal development|metabolic process|negative regulation of gene expression|regulation of apoptotic process|,molecular_function|catalytic activity|transcription factor binding|,10,0.3,0.451,10,0.5,4.2,0.5,4.18,4.18,0.226,0,0,-0.5,1.4
ENSMUSG00000024639,GNAQ,"guanine nucleotide binding protein, alpha q polypeptide",nucleus|lysosomal membrane|cytosol|heterotrimeric G-protein complex|heterotrimeric G-protein complex|plasma membrane|caveola|membrane|membrane|protein complex|extracellular vesicular exosome|,skeletal system development|action potential|GTP catabolic process|negative regulation of protein kinase activity|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|activation of phospholipase C activity|glutamate receptor signaling pathway|heart development|post-embryonic development|neuron remodeling|forebrain neuron development|regulation of catenin import into nucleus|maternal behavior|embryonic digit morphogenesis|negative regulation of apoptotic process|negative regulation of potassium ion transport|positive regulation of GTPase activity|positive regulation of GTPase activity|regulation of melanocyte differentiation|developmental pigmentation|positive regulation of smooth muscle cell proliferation|protein stabilization|phospholipase C-activating dopamine receptor signaling pathway|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|signal transducer activity|GTPase activator activity|GTPase activator activity|protein binding|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|type 2A serotonin receptor binding|type 2A serotonin receptor binding|protein complex binding|metal ion binding|,9,1,2.01,9,1,2.41,1,4.16,4.16,0.227,0,0,-0.8,2
ENSMUSG00000027455,NSFL1C,NSFL1 (p97) cofactor (p47),nucleus|chromosome|cytoplasm|Golgi apparatus|cytosol|plasma membrane|intermediate filament cytoskeleton|,Golgi organization|membrane fusion|,protein binding|phospholipid binding|lipid binding|ubiquitin binding|ATPase binding|,10,0.5,4.6,10,-0.2,0.557,0.4,4.16,4.16,0.227,0,0,-0.7,1.3
ENSMUSG00000079615,HSPA14,heat shock protein 14,cytoplasm|cytosol|ribosome|membrane|,biological_process|,nucleotide binding|ATP binding|,10,1.1,2.43,10,0.4,2.72,0.5,4.12,4.12,0.229,0,0,-0.2,1.7
ENSMUSG00000056370,SFTPB,surfactant associated protein B,extracellular region|extracellular space|cytoplasm|lysosome|multivesicular body|alveolar lamellar body|,lipid metabolic process|sphingolipid metabolic process|respiratory gaseous exchange|,None,10,0.2,0.473,10,0.5,4.39,0.4,4.12,4.12,0.229,0,0,-1.3,1.6
ENSMUSG00000031493,GGN,gametogenetin,nucleus|nuclear envelope|nucleolus|cytoplasm|integral component of membrane|cytoplasmic vesicle|perinuclear region of cytoplasm|,protein complex assembly|multicellular organismal development|spermatogenesis|protein localization|cell differentiation|,protein binding|protein dimerization activity|,10,-1.8,1.78,10,0.5,3.46,0.5,4.07,4.07,0.232,0,0,-2,1.9
ENSMUSG00000002732,FKBP7,FK506 binding protein 7,endoplasmic reticulum|endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|calcium ion binding|protein binding|FK506 binding|isomerase activity|metal ion binding|,10,-0.3,0.341,10,-0.7,4.59,-0.6,4.04,-4.04,0.233,0,0,-1.6,0.1
ENSMUSG00000074582,ARFGEF2,ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited),Golgi membrane|cytoplasm|endosome|Golgi apparatus|trans-Golgi network|trans-Golgi network|microtubule organizing center|cytosol|cytoskeleton|axonemal microtubule|membrane|cell junction|cytoplasmic vesicle|asymmetric synapse|symmetric synapse|cell projection|dendritic spine|synapse|recycling endosome|,receptor recycling|transport|exocytosis|Golgi to plasma membrane transport|endosome organization|endomembrane system organization|protein transport|vesicle-mediated transport|regulation of ARF protein signal transduction|positive regulation of tumor necrosis factor production|intracellular signal transduction|positive regulation of GTPase activity|positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|myosin binding|protein kinase A regulatory subunit binding|GABA receptor binding|,10,-0.2,0.595,10,-0.6,4.49,-0.4,4.04,-4.04,0.233,0,0,-1.5,0.2
ENSMUSG00000024581,NAPG,N-ethylmaleimide sensitive fusion protein attachment protein gamma,mitochondrion|lysosomal membrane|membrane|extracellular vesicular exosome|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,None,10,0.9,4.55,10,-0.5,5.32,-0.5,4.02,-4.02,0.234,0,0,-1.2,1.7
ENSMUSG00000018363,SMURF2,SMAD specific E3 ubiquitin protein ligase 2,ubiquitin ligase complex|nucleus|cytoplasm|plasma membrane|membrane|,ubiquitin-dependent protein catabolic process|transforming growth factor beta receptor signaling pathway|protein ubiquitination|ubiquitin-dependent SMAD protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|transforming growth factor beta receptor binding|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|identical protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|SMAD binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,0.527,10,0.9,4.26,0.8,3.97,3.97,0.237,0,0,0,1.9
ENSMUSG00000098034,SERPINB10,"serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10",cellular_component|extracellular space|nucleus|cytoplasm|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|negative regulation of proteolysis|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.5,0.716,10,0.7,4.66,0.6,3.95,3.95,0.238,0,0,-0.6,1.6
ENSMUSG00000048234,RNF149,ring finger protein 149,membrane|membrane|integral component of membrane|extracellular vesicular exosome|,protein ubiquitination|regulation of protein stability|cellular response to drug|negative regulation of MAPK cascade|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,0.764,10,-0.5,3.54,-0.4,3.95,-3.95,0.238,0,0,-1.6,0.4
ENSMUSG00000028098,RNF115,ring finger protein 115,cytoplasm|cytosol|,protein autoubiquitination|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,1.13,10,0.4,3.24,0.3,3.94,3.94,0.238,0,0,-0.3,1.2
ENSMUSG00000041044,LRIT1,"leucine-rich repeat, immunoglobulin-like and transmembrane domains 1",endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,biological_process|,molecular_function|,10,-0.3,1.01,10,-0.4,3.43,-0.4,3.93,-3.93,0.239,0,0,-1.3,0.6
ENSMUSG00000020448,RNF185,ring finger protein 185,cellular_component|mitochondrion|mitochondrial outer membrane|endoplasmic reticulum|membrane|integral component of membrane|,autophagy|biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,1.37,10,0.6,3.16,0.5,3.92,3.92,0.239,0,0,-0.2,1.6
ENSMUSG00000050762,PRSS27,"protease, serine 27",extracellular region|plasma membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.3,0.536,10,0.6,3.96,0.5,3.9,3.9,0.241,0,0,-0.1,1.4
ENSMUSG00000022272,MYO10,myosin X,ruffle|nucleolus|cytoplasm|cytoskeleton|plasma membrane|membrane|myosin complex|lamellipodium|filopodium|cell projection|neuron projection|neuronal cell body|,transport|regulation of cell shape|positive regulation of cell-cell adhesion|cell motility|regulation of filopodium assembly|,nucleotide binding|motor activity|actin binding|protein binding|calmodulin binding|ATP binding|spectrin binding|actin filament binding|,10,-1.1,1.91,10,-1.9,3.69,-1.8,3.88,-3.88,0.242,0,0,-3,0.5
ENSMUSG00000031913,VPS4A,vacuolar protein sorting 4a (yeast),ESCRT III complex|cytoplasm|cytoplasm|endosome|early endosome|membrane|midbody|perinuclear region of cytoplasm|perinuclear region of cytoplasm|extracellular vesicular exosome|,cytokinesis|transport|cell cycle|abscission|protein transport|vesicle-mediated transport|endosomal transport|cytokinesis checkpoint|negative regulation of cytokinesis|cell division|,nucleotide binding|protein binding|ATP binding|protein C-terminus binding|hydrolase activity|Rho GTPase binding|protein domain specific binding|,10,0,0,10,0.7,6.01,0.6,3.87,3.87,0.242,0,0,-0.1,1.7
ENSMUSG00000029375,CXCL15,chemokine (C-X-C motif) ligand 15,extracellular region|extracellular space|,chemotaxis|inflammatory response|immune response|hemopoiesis|neutrophil chemotaxis|,cytokine activity|chemokine activity|,10,-0.5,4.5,9,-1.5,2.4,-0.4,3.85,-3.85,0.243,0,0,-2.6,0.2
ENSMUSG00000024480,AP3S1,"adaptor-related protein complex 3, sigma 1 subunit",intracellular|cell|Golgi apparatus|trans-Golgi network|membrane|membrane coat|AP-3 adaptor complex|cytoplasmic vesicle|,transport|intracellular protein transport|anterograde axon cargo transport|protein transport|vesicle-mediated transport|anterograde synaptic vesicle transport|,protein transporter activity|,10,-0.6,1.47,10,0.7,4.42,0.5,3.84,3.84,0.244,0,0,-1.3,1.5
ENSMUSG00000063260,SYT10,synaptotagmin X,synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,transport|regulation of calcium ion-dependent exocytosis|,transporter activity|protein binding|identical protein binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,0.6,0.573,10,0.4,3.73,0.4,3.82,3.82,0.245,0,0,-0.3,1.3
ENSMUSG00000030327,NECAP1,NECAP endocytosis associated 1,plasma membrane|coated pit|membrane|clathrin vesicle coat|cytoplasmic vesicle|,transport|endocytosis|protein transport|,protein binding|,9,0.2,0.956,10,-0.7,6.47,-0.7,3.81,-3.81,0.245,0,0,-1.8,0.5
ENSMUSG00000003380,RABAC1,Rab acceptor 1 (prenylated),cytoplasm|Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,None,protein binding|protein C-terminus binding|identical protein binding|proline-rich region binding|,10,-0.5,5.83,10,0.9,1.47,-0.4,3.81,-3.81,0.245,0,0,-1.3,1.3
ENSMUSG00000036469,1-Mar,membrane-associated ring finger (C3HC4) 1,lysosome|lysosomal membrane|endosome|endoplasmic reticulum membrane|Golgi apparatus|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|early endosome membrane|early endosome membrane|late endosome membrane|late endosome membrane|trans-Golgi network membrane|,protein polyubiquitination|protein polyubiquitination|immune system process|antigen processing and presentation of peptide antigen via MHC class II|antigen processing and presentation of peptide antigen via MHC class II|immune response|immune response|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|MHC protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,-0.7,6.47,9,0,0,-0.7,3.79,-3.79,0.246,0,0,-1.9,0.1
ENSMUSG00000048012,ZFP473,zinc finger protein 473,intracellular|nucleus|Cajal body|,"regulation of transcription, DNA-templated|histone mRNA 3'-end processing|",nucleic acid binding|DNA binding|metal ion binding|,10,-1.2,5.88,10,0.2,0.283,-0.6,3.78,-3.78,0.247,0,0,-2,0.3
ENSMUSG00000032115,HYOU1,hypoxia up-regulated 1,endoplasmic reticulum|smooth endoplasmic reticulum|membrane|extracellular vesicular exosome|,response to hypoxia|response to ischemia|response to stress|,nucleotide binding|ATP binding|,8,1.2,6.74,8,-0.1,0.00237,1.2,3.78,3.78,0.247,0,0,0,2
ENSMUSG00000018868,PNPLA5,patatin-like phospholipase domain containing 5,cellular_component|,lipid metabolic process|biological_process|metabolic process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.5,4.32,10,-0.1,0.137,-0.5,3.71,-3.71,0.251,0,0,-1.6,0.5
ENSMUSG00000024583,TXNL1,thioredoxin-like 1,proteasome complex|nucleus|cytoplasm|extracellular vesicular exosome|,glycerol ether metabolic process|transport|cell redox homeostasis|oxidation-reduction process|,protein disulfide oxidoreductase activity|disulfide oxidoreductase activity|,10,-0.5,4.65,10,0,0,-0.4,3.7,-3.7,0.251,0,0,-1.5,0.4
ENSMUSG00000020937,PLCD3,"phospholipase C, delta 3",cytoplasm|cytosol|membrane|,angiogenesis|lipid metabolic process|signal transduction|lipid catabolic process|intracellular signal transduction|regulation of cell proliferation|labyrinthine layer blood vessel development|,phosphatidylinositol phospholipase C activity|signal transducer activity|calcium ion binding|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|,10,-0.6,3.9,10,-0.2,0.325,-0.5,3.67,-3.67,0.253,0,0,-1.6,0.2
ENSMUSG00000031378,ABCD1,"ATP-binding cassette, sub-family D (ALD), member 1",cytoplasm|mitochondrion|peroxisome|peroxisomal membrane|peroxisomal membrane|integral component of peroxisomal membrane|membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,ATP catabolic process|fatty acid beta-oxidation|fatty acid beta-oxidation|transport|peroxisome organization|peroxisomal long-chain fatty acid import|fatty-acyl-CoA transport|long-chain fatty acid catabolic process|very long-chain fatty acid catabolic process|transmembrane transport|,"nucleotide binding|peroxisomal fatty-acyl-CoA transporter activity|protein binding|ATP binding|ATPase activity|enzyme binding|ATPase activity, coupled to transmembrane movement of substances|identical protein binding|protein homodimerization activity|",10,0.8,4.45,10,0.3,0.388,0.6,3.67,3.67,0.253,0,0,0,1.8
ENSMUSG00000048826,DACT2,"dapper homolog 2, antagonist of beta-catenin (xenopus)",mitochondrion|,hematopoietic progenitor cell differentiation|epithelial cell morphogenesis|negative regulation of cell adhesion|multicellular organismal development|skin development|inner medullary collecting duct development|negative regulation of nodal signaling pathway|negative regulation of nodal signaling pathway|,protein kinase C binding|protein binding|beta-catenin binding|transcription factor binding|protein kinase A binding|delta-catenin binding|,10,0,0,10,0.7,5.01,0.5,3.66,3.66,0.253,0,0,-0.1,1.7
ENSMUSG00000043705,CAPN13,calpain 13,intracellular|cytoplasm|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,-1,1.81,10,-1,2.09,-1,3.65,-3.65,0.254,0,0,-2,1.1
ENSMUSG00000047502,MROH7,maestro heat-like repeat family member 7,extracellular space|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.6,3.37,10,-0.2,0.784,-0.5,3.63,-3.63,0.255,0,0,-1.5,0.8
ENSMUSG00000054693,ADAM10,a disintegrin and metallopeptidase domain 10,intracellular|cell|nucleus|cytoplasm|Golgi apparatus|Golgi-associated vesicle|trans-Golgi network|cell surface|postsynaptic density|membrane|integral component of membrane|extracellular vesicular exosome|perinuclear endoplasmic reticulum|tetraspanin-enriched microdomain|,in utero embryonic development|protein phosphorylation|proteolysis|membrane protein ectodomain proteolysis|nucleocytoplasmic transport|negative regulation of cell adhesion|Notch signaling pathway|Notch receptor processing|positive regulation of cell proliferation|positive regulation of T cell chemotaxis|positive regulation of cell growth|positive regulation of cell migration|response to tumor necrosis factor|monocyte activation|PMA-inducible membrane protein ectodomain proteolysis|constitutive protein ectodomain proteolysis|,endopeptidase activity|metalloendopeptidase activity|protein binding|peptidase activity|metallopeptidase activity|metallopeptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|SH3 domain binding|protein kinase binding|SH2 domain binding|protein homodimerization activity|metal ion binding|,10,0.1,0.435,10,0.4,3.85,0.3,3.62,3.62,0.256,0,0,-0.4,1.3
ENSMUSG00000044254,PCSK9,proprotein convertase subtilisin/kexin type 9,extracellular region|extracellular space|extracellular space|extracellular space|cytoplasm|lysosome|endosome|early endosome|late endosome|endoplasmic reticulum|endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|plasma membrane|cell surface|ER to Golgi transport vesicle|perinuclear region of cytoplasm|,negative regulation of receptor recycling|positive regulation of receptor internalization|proteolysis|proteolysis|lipid metabolic process|triglyceride metabolic process|phospholipid metabolic process|apoptotic process|lysosomal transport|steroid metabolic process|cholesterol metabolic process|cellular response to starvation|cellular response to starvation|regulation of receptor activity|negative regulation of low-density lipoprotein particle clearance|protein processing|protein autoprocessing|protein autoprocessing|neuron differentiation|neuron differentiation|low-density lipoprotein receptor particle metabolic process|low-density lipoprotein particle receptor catabolic process|low-density lipoprotein particle receptor catabolic process|regulation of low-density lipoprotein particle receptor catabolic process|cellular response to insulin stimulus|cellular response to insulin stimulus|lipoprotein metabolic process|cholesterol homeostasis|cholesterol homeostasis|regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|,serine-type endopeptidase activity|serine-type endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|sodium channel inhibitor activity|low-density lipoprotein particle binding|apolipoprotein binding|very-low-density lipoprotein particle binding|apolipoprotein receptor binding|protein self-association|poly(A) RNA binding|low-density lipoprotein particle receptor binding|low-density lipoprotein particle receptor binding|very-low-density lipoprotein particle receptor binding|,10,0,0,10,0.5,5.58,0.5,3.61,3.61,0.256,0,0,-0.2,1.6
ENSMUSG00000031217,EFNB1,ephrin B1,nucleus|cytoplasm|plasma membrane|membrane|integral component of membrane|membrane raft|synapse|extracellular vesicular exosome|,neural crest cell migration|multicellular organismal development|nervous system development|axon guidance|embryonic pattern specification|cell differentiation|positive regulation of T cell proliferation|ephrin receptor signaling pathway|,protein binding|ephrin receptor binding|,10,-0.4,5.76,10,0,0,-0.4,3.6,-3.6,0.257,0,0,-1.4,0.4
ENSMUSG00000037376,TRMT6,tRNA methyltransferase 6,cellular_component|nucleus|,translational initiation|regulation of translational initiation|tRNA processing|,translation initiation factor activity|poly(A) RNA binding|,9,-1.3,3.5,8,0.3,0.987,0.4,3.59,3.59,0.257,0,0,-2,1.1
ENSMUSG00000038648,CREB3L2,cAMP responsive element binding protein 3-like 2,intracellular|cell|nucleus|endoplasmic reticulum|membrane|integral component of membrane|,"chondrocyte differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|ER to Golgi vesicle-mediated transport|response to unfolded protein|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|cartilage development|",DNA binding|sequence-specific DNA binding transcription factor activity|cAMP response element binding|cAMP response element binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|,10,-0.5,1.43,10,-0.3,2.48,-0.4,3.59,-3.59,0.257,0,0,-1.4,0.3
ENSMUSG00000060985,TDRD5,tudor domain containing 5,cytoplasm|chromatoid body|pi-body|,multicellular organismal development|spermatogenesis|spermatid development|cell differentiation|P granule organization|DNA methylation involved in gamete generation|,molecular_function|,9,-0.5,1.01,9,-0.8,2.99,-0.7,3.57,-3.57,0.259,0,0,-1.9,0.3
ENSMUSG00000053931,CNN3,"calponin 3, acidic",postsynaptic density|dendrite|neuronal cell body|dendritic spine|,actomyosin structure organization|negative regulation of ATPase activity|,actin binding|protein binding|calmodulin binding|microtubule binding|,10,0,0,10,-0.4,4.9,-0.3,3.56,-3.56,0.259,0,0,-1.4,0.3
ENSMUSG00000061787,RPS17,ribosomal protein S17,intracellular|ribosome|membrane|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,ribosomal small subunit assembly|rRNA processing|translation|translational elongation|erythrocyte homeostasis|ribosomal small subunit biogenesis|,structural constituent of ribosome|poly(A) RNA binding|,5,0,0,5,0.6,5.41,0.6,3.52,3.52,0.262,0,0,-0.3,2
ENSMUSG00000025932,EYA1,eyes absent 1 homolog (Drosophila),cell|nucleus|nucleus|cytoplasm|cytoplasm|protein-DNA complex|protein complex|,"establishment of mitotic spindle orientation|establishment of mitotic spindle orientation|metanephros development|ureteric bud development|branching involved in ureteric bud morphogenesis|outflow tract morphogenesis|DNA repair|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein dephosphorylation|cellular response to DNA damage stimulus|multicellular organismal development|pattern specification process|pattern specification process|mesodermal cell fate specification|organ morphogenesis|response to ionizing radiation|striated muscle tissue development|chromatin modification|histone dephosphorylation|protein sumoylation|cellular protein localization|establishment or maintenance of apical/basal cell polarity|peptidyl-tyrosine dephosphorylation|aorta morphogenesis|ear morphogenesis|inner ear morphogenesis|inner ear morphogenesis|outer ear morphogenesis|middle ear morphogenesis|cell fate commitment|regulation of neuron differentiation|regulation of neuron differentiation|positive regulation of DNA repair|positive regulation of Notch signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|neuron fate specification|embryonic skeletal system morphogenesis|semicircular canal morphogenesis|anatomical structure development|positive regulation of epithelial cell proliferation|pharyngeal system development|lung epithelial cell differentiation|otic vesicle development|otic vesicle morphogenesis|positive regulation of secondary heart field cardioblast proliferation|cochlea morphogenesis|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|",RNA binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|metal ion binding|,10,-0.1,0.203,10,-0.6,4.97,-0.6,3.52,-3.52,0.262,0,0,-1.7,0.1
ENSMUSG00000021242,NPC2,Niemann-Pick type C2,extracellular region|intracellular|cell|lysosome|lysosome|endoplasmic reticulum|extracellular vesicular exosome|,lipid metabolic process|steroid metabolic process|cholesterol metabolic process|cholesterol transport|cholesterol transport|cholesterol transport|intracellular sterol transport|intracellular sterol transport|intracellular cholesterol transport|intracellular cholesterol transport|cholesterol efflux|cholesterol efflux|cholesterol homeostasis|cholesterol homeostasis|,cholesterol binding|cholesterol binding|cholesterol binding|enzyme binding|,10,0.3,2.36,10,0.3,1.38,0.3,3.51,3.51,0.262,0,0,-0.5,1.3
ENSMUSG00000028986,KLHL7,kelch-like 7,nucleus|cytoplasm|plasma membrane|Cul3-RING ubiquitin ligase complex|,protein ubiquitination|,protein homodimerization activity|,10,-1.3,4.87,10,-0.2,0.511,-0.2,3.5,-3.5,0.263,0,0,-2,0.2
ENSMUSG00000035284,VPS13C,vacuolar protein sorting 13C (yeast),extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.1,0.624,10,-0.9,4.16,-0.8,3.49,-3.49,0.263,0,0,-2,0.6
ENSMUSG00000053581,ZFAND2A,"zinc finger, AN1-type domain 2A",proteasome complex|nucleus|cytoplasm|,positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular response to arsenic-containing substance|,protein binding|zinc ion binding|metal ion binding|,10,0.5,1.18,10,0.4,2.74,0.5,3.46,3.46,0.265,0,0,-0.3,1.4
ENSMUSG00000014177,TVP23B,trans-golgi network vesicle protein 23B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.9,0.677,9,0.8,2.95,0.8,3.42,3.42,0.267,0,0,-0.2,1.9
ENSMUSG00000063457,RPS15,ribosomal protein S15,ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|,ribosomal small subunit assembly|ribosomal small subunit export from nucleus|osteoblast differentiation|rRNA processing|translation|ribosomal small subunit biogenesis|,RNA binding|structural constituent of ribosome|protein binding|poly(A) RNA binding|,2,0.5,1.54,2,0.5,2.11,0.5,3.42,3.42,0.267,0,0,-0.9,2
ENSMUSG00000040950,MGL2,macrophage galactose N-acetyl-galactosamine specific lectin 2,None,None,carbohydrate binding|,10,-0.7,2.33,10,-1.3,2.88,-0.8,3.42,-3.42,0.267,0,0,-2,0.2
ENSMUSG00000040711,SH3PXD2B,SH3 and PX domains 2B,podosome|cytoplasm|cell junction|cell projection|,skeletal system development|skeletal system development|eye development|eye development|superoxide metabolic process|heart development|heart development|extracellular matrix disassembly|cell differentiation|positive regulation of fat cell differentiation|bone development|bone development|adipose tissue development|podosome assembly|protein localization to membrane|,"phosphatidylinositol-5-phosphate binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol binding|SH2 domain binding|phosphatidylinositol-4-phosphate binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0.2,1.13,10,-0.5,5.61,-0.5,3.42,-3.42,0.267,0,0,-1.5,0.5
ENSMUSG00000028466,CREB3,cAMP responsive element binding protein 3,Golgi membrane|nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|cytosol|membrane|integral component of membrane|nuclear body|integral component of endoplasmic reticulum membrane|neuronal cell body|,"regulation of cell growth|positive regulation of defense response to virus by host|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|chemotaxis|response to unfolded protein|positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response|establishment of viral latency|release from viral latency|positive regulation of cell migration|regulation of cell proliferation|cytoplasmic sequestering of transcription factor|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of calcium ion transport|positive regulation of monocyte chemotaxis|positive regulation of deacetylase activity|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|cAMP response element binding protein binding|CCR1 chemokine receptor binding|protein homodimerization activity|sequence-specific DNA binding|,10,0,0,10,-1.6,6.81,-1.6,3.42,-3.42,0.267,0,0,-3,0.3
ENSMUSG00000021131,ERH,enhancer of rudimentary homolog (Drosophila),membrane|midbody|,osteoblast differentiation|cell cycle|,poly(A) RNA binding|,10,-0.5,4.68,9,0.1,0.37,-0.4,3.41,-3.41,0.268,0,0,-1.4,1.3
ENSMUSG00000044037,ALS2CL,ALS2 C-terminal like,cytoplasm|cytoplasmic membrane-bounded vesicle|,endosome organization|endosome organization|protein localization|regulation of Rho protein signal transduction|,Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|protein binding|Rab GTPase binding|identical protein binding|,10,-0.2,2.55,10,-0.2,1.07,-0.2,3.4,-3.4,0.268,0,0,-1.6,0.2
ENSMUSG00000042328,HPS4,Hermansky-Pudlak syndrome 4 homolog (human),cytoplasm|cytoplasm|lysosome|lysosome|membrane|membrane|cytoplasmic membrane-bounded vesicle|BLOC-3 complex|melanosome|melanosome|platelet dense granule|,protein targeting|protein targeting|organelle organization|lysosome organization|lysosome organization|blood coagulation|melanocyte differentiation|protein stabilization|protein stabilization|,protein homodimerization activity|protein homodimerization activity|protein dimerization activity|protein dimerization activity|,10,0.3,2.14,10,0.4,1.53,0.4,3.39,3.39,0.269,0,0,-0.2,1.6
ENSMUSG00000025525,APOOL,apolipoprotein O-like,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.9,4.55,10,-1,1.68,0.8,3.39,3.39,0.269,0,0,-1,2
ENSMUSG00000020773,TRIM47,tripartite motif-containing 47,cellular_component|intracellular|nucleus|cytoplasm|,biological_process|,zinc ion binding|metal ion binding|,10,0.1,0.308,10,0.6,3.83,-0.9,3.38,-3.38,0.27,0,0,-1.8,1.3
ENSMUSG00000021248,TMED10,transmembrane emp24-like trafficking protein 10 (yeast),Golgi membrane|intracellular|cell|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|cis-Golgi network|cis-Golgi network|plasma membrane|membrane|integral component of membrane|COPI-coated vesicle|secretory granule membrane|cytoplasmic vesicle|zymogen granule membrane|zymogen granule membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|gamma-secretase complex|,transport|intracellular protein transport|intracellular protein transport|Golgi organization|Golgi organization|protein transport|vesicle-mediated transport|beta-amyloid formation|COPI-coated vesicle budding|protein oligomerization|,syntaxin binding|protein complex binding|,10,0.5,1.9,10,0.5,1.69,0.5,3.36,3.36,0.271,0,0,-1.6,1.5
ENSMUSG00000040044,ORC3,"origin recognition complex, subunit 3",origin recognition complex|nucleus|nuclear origin of replication recognition complex|,DNA replication|neural precursor cell proliferation|,molecular_function|DNA binding|,10,-0.9,2.3,9,1,5.43,0.6,3.35,3.35,0.272,0,0,-1.3,1.9
ENSMUSG00000019877,SERINC1,serine incorporator 1,endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,lipid metabolic process|phosphatidylserine metabolic process|sphingolipid metabolic process|phospholipid biosynthetic process|L-serine transport|positive regulation of transferase activity|L-alpha-amino acid transmembrane transport|,L-serine transmembrane transporter activity|,10,0.7,0.935,10,1,2.77,0.7,3.34,3.34,0.272,0,0,-0.7,2
ENSMUSG00000031355,ARHGAP6,Rho GTPase activating protein 6,intracellular|cytoplasm|actin cytoskeleton|,actin filament organization|signal transduction|activation of phospholipase C activity|positive regulation of phospholipase activity|positive regulation of Rho GTPase activity|regulation of GTPase activity|positive regulation of GTPase activity|focal adhesion assembly|negative regulation of stress fiber assembly|negative regulation of focal adhesion assembly|,GTPase activator activity|Rho GTPase activator activity|phospholipase activator activity|SH3 domain binding|phospholipase binding|,10,1,0.777,10,-0.3,3.29,-0.3,3.34,-3.34,0.272,0,0,-1.2,1.5
ENSMUSG00000039476,PRRX2,paired related homeobox 2,nucleus|,"positive regulation of mesenchymal cell proliferation|regulation of transcription, DNA-templated|multicellular organismal development|embryonic limb morphogenesis|inner ear morphogenesis|middle ear morphogenesis|positive regulation of smoothened signaling pathway|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|artery morphogenesis|cartilage development|",DNA binding|sequence-specific DNA binding|HMG box domain binding|,10,0.3,0.257,10,-0.7,5.67,-0.5,3.33,-3.33,0.273,0,0,-1.7,0.6
ENSMUSG00000021239,VSX2,visual system homeobox 2,intracellular|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of cell proliferation|negative regulation of cell proliferation|camera-type eye development|cell fate commitment|positive regulation of transcription from RNA polymerase II promoter|retinal bipolar neuron differentiation|retina morphogenesis in camera-type eye|",DNA binding|protein binding|sequence-specific DNA binding|,9,-0.3,1.4,9,-0.6,2.27,-0.4,3.32,-3.32,0.273,0,0,-1.6,1.3
ENSMUSG00000070394,TMEM256,transmembrane protein 256,mitochondrial inner membrane|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.8,4.2,10,0,0,0.6,3.32,3.32,0.273,0,0,-0.1,1.8
ENSMUSG00000041765,UBAC2,ubiquitin associated domain containing 2,endoplasmic reticulum|membrane|integral component of membrane|,protein localization to endoplasmic reticulum|,molecular_function|,10,0.4,0.458,10,-0.4,3.58,-0.4,3.32,-3.32,0.273,0,0,-1.4,1
ENSMUSG00000063689,HIST2H2AB,"histone cluster 2, H2ab",nucleosome|nucleus|chromosome|extracellular vesicular exosome|,None,DNA binding|protein heterodimerization activity|,10,0.5,5.64,10,-0.2,0.642,0.5,3.3,3.3,0.275,0,0,-0.6,1.7
ENSMUSG00000023965,FBXL17,F-box and leucine-rich repeat protein 17,cellular_component|,biological_process|,molecular_function|,10,-0.3,2.32,10,-0.5,1.19,-0.3,3.28,-3.28,0.276,0,0,-1.5,0.3
ENSMUSG00000023927,SATB1,special AT-rich sequence binding protein 1,chromatin|nucleus|nuclear heterochromatin|nuclear matrix|PML body|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|chromatin organization|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|epidermis development|chromatin modification|histone methylation|T cell activation|CD4-positive, alpha-beta T cell differentiation|CD8-positive, alpha-beta T cell differentiation|activated T cell proliferation|reflex|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|,10,0.4,1.64,10,0.5,1.87,0.4,3.27,3.27,0.277,0,0,-0.9,1.5
ENSMUSG00000031783,POLR2C,polymerase (RNA) II (DNA directed) polypeptide C,"nucleus|nucleus|DNA-directed RNA polymerase II, core complex|DNA-directed RNA polymerase II, core complex|cytoplasm|cytoplasm|microtubule cytoskeleton|","transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II activity|DNA binding|DNA-directed RNA polymerase activity|protein binding|protein dimerization activity|,5,1.1,3.98,2,0.2,0.212,1,3.26,3.26,0.277,0,0,-0.5,2
ENSMUSG00000032932,HSPA13,"heat shock protein 70 family, member 13",endoplasmic reticulum|intracellular membrane-bounded organelle|extracellular vesicular exosome|,None,nucleotide binding|ATP binding|,10,0.6,1.12,10,-0.9,4.98,-0.5,3.25,-3.25,0.278,0,0,-1.8,0.8
ENSMUSG00000014856,TMEM208,transmembrane protein 208,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,autophagy|biological_process|,molecular_function|,10,-0.3,2.75,10,-1.2,2.72,-0.3,3.24,-3.24,0.279,0,0,-2,1
ENSMUSG00000021975,INTS9,integrator complex subunit 9,nucleus|cytoplasm|integrator complex|,snRNA processing|,molecular_function|,8,0.5,2.41,7,1,1.95,0.6,3.24,3.24,0.279,0,0,-0.8,2
ENSMUSG00000000804,USP32,ubiquitin specific peptidase 32,Golgi apparatus|,proteolysis|,ubiquitin thiolesterase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,-0.6,0.527,10,0.6,4.95,0.5,3.23,3.23,0.28,0,0,-1.5,1.4
ENSMUSG00000051864,TBC1D22A,"TBC1 domain family, member 22a",cellular_component|,biological_process|regulation of Rab GTPase activity|,GTPase activator activity|Rab GTPase activator activity|protein homodimerization activity|,9,0.2,0.614,10,0.5,3.7,0.4,3.22,3.22,0.28,0,0,-1.4,1.3
ENSMUSG00000031919,TMED6,transmembrane emp24 protein transport domain containing 6,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,9,1.5,5.96,9,-1.5,5.68,-1.4,3.22,-3.22,0.28,0,0,-3,2.6
ENSMUSG00000039438,TTC36,tetratricopeptide repeat domain 36,cellular_component|,biological_process|,molecular_function|,10,0.2,0.52,10,0.5,2.89,0.5,3.18,3.18,0.283,0,0,-0.2,1.6
ENSMUSG00000034163,ZFC3H1,"zinc finger, C3H1-type containing",extracellular space|,biological_process|,poly(A) RNA binding|,10,-0.4,1.01,10,-0.4,2.37,-0.4,3.18,-3.18,0.283,0,0,-1.4,1
ENSMUSG00000006024,NAPA,N-ethylmaleimide sensitive fusion protein attachment protein alpha,intracellular|cell|membrane|membrane|synaptobrevin 2-SNAP-25-syntaxin-1a complex|synaptobrevin 2-SNAP-25-syntaxin-1a complex|extracellular vesicular exosome|,"transport|intracellular protein transport|brain development|regulation of synaptic vesicle priming|protein transport|vesicle-mediated transport|neuron differentiation|synaptic transmission, glutamatergic|SNARE complex disassembly|apical protein localization|",SNARE binding|protein binding|syntaxin binding|,9,0.5,3.11,8,-1.1,6.23,-1.1,3.18,-3.18,0.283,0,0,-2,0.8
ENSMUSG00000061118,DNAJC30,"DnaJ (Hsp40) homolog, subfamily C, member 30",mitochondrion|,biological_process|,None,10,-0.2,1.5,10,-0.4,2.15,-0.3,3.17,-3.17,0.284,0,0,-1.4,0.5
ENSMUSG00000015478,RNF5,ring finger protein 5,mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|,response to bacterium|negative regulation of autophagy|protein ubiquitination|protein destabilization|cellular protein catabolic process|protein K63-linked ubiquitination|protein K48-linked ubiquitination|ER-associated misfolded protein catabolic process|regulation of autophagic vacuole assembly|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.7,2.9,10,1.2,4.83,1.1,3.16,3.16,0.285,0,0,-0.8,2
ENSMUSG00000039656,RXRB,retinoid X receptor beta,nucleus|,"in utero embryonic development|maternal placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|regulation of myelination|steroid hormone mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|retinoic acid receptor signaling pathway|retinoic acid receptor signaling pathway|ventricular cardiac muscle cell differentiation|ventricular cardiac muscle cell differentiation|cardiac muscle cell proliferation|cellular response to retinoic acid|positive regulation of receptor activity|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|9-cis retinoic acid receptor activity|9-cis retinoic acid receptor activity|protein binding|zinc ion binding|thyroid hormone receptor coactivator activity|protein homodimerization activity|vitamin D receptor binding|retinoic acid receptor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|thyroid hormone receptor binding|protein heterodimerization activity|,10,0.2,0.626,10,0.3,2.74,0.3,3.15,3.15,0.285,0,0,-0.5,1.3
ENSMUSG00000032867,FBXW8,F-box and WD-40 domain protein 8,cytoplasm|Golgi apparatus|SCF ubiquitin ligase complex|Cul7-RING ubiquitin ligase complex|Cul7-RING ubiquitin ligase complex|perinuclear region of cytoplasm|3M complex|,ubiquitin-dependent protein catabolic process|Golgi organization|cell proliferation|protein ubiquitination|positive regulation of dendrite morphogenesis|spongiotrophoblast layer development|labyrinthine layer blood vessel development|,ubiquitin-protein transferase activity|protein binding|,10,-0.1,0.3,10,-1.1,5.72,-1.1,3.13,-3.13,0.287,0,0,-2,0.3
ENSMUSG00000020702,CCL1,chemokine (C-C motif) ligand 1,extracellular region|extracellular space|,chemotaxis|immune response|,cytokine activity|protein binding|chemokine activity|,10,0.1,0.198,10,0.7,4.14,0.6,3.13,3.13,0.287,0,0,-0.8,1.7
ENSMUSG00000058594,FBXO18,F-box protein 18,nucleus|,"DNA catabolic process, endonucleolytic|positive regulation of protein phosphorylation|response to intra-S DNA damage checkpoint signaling|response to intra-S DNA damage checkpoint signaling|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage|",nucleotide binding|molecular_function|DNA binding|ATP-dependent DNA helicase activity|helicase activity|ATP binding|hydrolase activity|,10,0.2,0.293,10,1,3.82,0.4,3.11,3.11,0.288,0,0,-0.2,1.9
ENSMUSG00000033487,FNDC3A,fibronectin type III domain containing 3A,acrosomal vesicle|Golgi apparatus|cytosol|vesicle membrane|membrane|membrane|integral component of membrane|cytoplasmic vesicle|,spermatid development|fertilization|single organismal cell-cell adhesion|Sertoli cell development|,poly(A) RNA binding|,10,-0.4,3.03,10,-0.3,0.484,-0.4,3.11,-3.11,0.288,0,0,-1.4,0.5
ENSMUSG00000003363,PLD3,"phospholipase D family, member 3",endoplasmic reticulum|membrane|integral component of membrane|extracellular vesicular exosome|,lipid metabolic process|metabolic process|lipid catabolic process|,catalytic activity|phospholipase D activity|hydrolase activity|N-acylphosphatidylethanolamine-specific phospholipase D activity|,10,-0.9,3.43,10,-0.5,0.717,-0.7,3.1,-3.1,0.289,0,0,-1.9,0.5
ENSMUSG00000024535,SNX24,sorting nexing 24,cellular_component|membrane|cytoplasmic vesicle|,transport|biological_process|protein transport|,molecular_function|lipid binding|phosphatidylinositol binding|,10,0.3,1.48,10,0.4,1.83,0.4,3.07,3.07,0.291,0,0,-0.7,1.6
ENSMUSG00000030754,COPB1,"coatomer protein complex, subunit beta 1",cytoplasm|Golgi apparatus|Golgi apparatus|Golgi-associated vesicle|plasma membrane|membrane|membrane|membrane coat|COPI vesicle coat|COPI-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|,transport|intracellular protein transport|intra-Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,structural molecule activity|,9,1,2.84,9,0.4,0.449,0.7,3.07,3.07,0.291,0,0,-0.1,1.9
ENSMUSG00000002957,AP2A2,"adaptor-related protein complex 2, alpha 2 subunit",plasma membrane|coated pit|membrane|membrane coat|clathrin adaptor complex|secretory granule|,transport|intracellular protein transport|endocytosis|protein transport|vesicle-mediated transport|,protein binding|lipid binding|protein transporter activity|,10,0.4,3.16,10,0.2,0.342,0.4,3.06,3.06,0.292,0,0,-0.2,1.7
ENSMUSG00000028049,SCAMP3,secretory carrier membrane protein 3,Golgi membrane|intracellular|cell|membrane|integral component of membrane|extracellular vesicular exosome|,transport|intracellular protein transport|response to organic substance|protein transport|response to retinoic acid|,None,10,0.3,3.78,10,0.1,0.189,0.3,3.06,3.06,0.292,0,0,-0.4,1.4
ENSMUSG00000074665,BPIFB4,"BPI fold containing family B, member 4",cellular_component|extracellular region|cytoplasm|,biological_process|,lipid binding|,10,0.9,1.73,10,0.4,1.91,0.5,3.06,3.06,0.292,0,0,-0.3,1.8
ENSMUSG00000039615,STUB1,STIP1 homology and U-Box containing protein 1,ubiquitin ligase complex|nucleus|cytoplasm|cytoplasm|plasma membrane|ubiquitin conjugating enzyme complex|nuclear inclusion body|intermediate filament cytoskeleton|extracellular vesicular exosome|,protein polyubiquitination|protein polyubiquitination|DNA repair|protein folding|ubiquitin-dependent protein catabolic process|misfolded or incompletely synthesized protein catabolic process|misfolded or incompletely synthesized protein catabolic process|cellular response to DNA damage stimulus|protein ubiquitination|ubiquitin-dependent SMAD protein catabolic process|positive regulation of protein ubiquitination|positive regulation of protein ubiquitination|regulation of glucocorticoid metabolic process|regulation of glucocorticoid metabolic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|protein maturation|protein autoubiquitination|protein K63-linked ubiquitination|cellular response to misfolded protein|cellular response to misfolded protein|positive regulation of chaperone-mediated protein complex assembly|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|enzyme binding|kinase binding|Hsp70 protein binding|Hsp70 protein binding|Hsp70 protein binding|protein binding, bridging|TPR domain binding|TPR domain binding|heat shock protein binding|ubiquitin protein ligase binding|ubiquitin-ubiquitin ligase activity|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|SMAD binding|misfolded protein binding|Hsp90 protein binding|Hsp90 protein binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.5,0.531,10,0.8,2.87,0.5,3.06,3.06,0.292,0,0,-0.4,1.7
ENSMUSG00000049969,PLEKHF2,"pleckstrin homology domain containing, family F (with FYVE domain) member 2",endosome|endoplasmic reticulum|membrane|transport vesicle|,transport|protein transport|,metal ion binding|,10,0,0,10,0.5,3.55,0.5,3.05,3.05,0.293,0,0,-1,1.8
ENSMUSG00000036989,TRIM3,tripartite motif-containing 3,intracellular|cytoplasm|cytoplasm|endosome|,transport|protein transport|protein ubiquitination|,ubiquitin-protein transferase activity|protein binding|zinc ion binding|metal ion binding|,10,0.4,2.17,10,0.9,1.48,0.5,3.05,3.05,0.293,0,0,-0.2,1.9
ENSMUSG00000025075,HABP2,hyaluronic acid binding protein 2,extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.8,4.31,10,-0.1,0.12,0.7,3.04,3.04,0.293,0,0,-0.1,2
ENSMUSG00000032363,ADAMTS7,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7",extracellular region|proteinaceous extracellular matrix|cell surface|extracellular matrix|,proteolysis|negative regulation of chondrocyte differentiation|proteolysis involved in cellular protein catabolic process|cellular response to interleukin-1|cellular response to tumor necrosis factor|cellular response to BMP stimulus|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.4,3.52,10,0.1,0.203,-0.3,3.04,-3.04,0.293,0,0,-1.4,0.5
ENSMUSG00000005505,KBTBD4,kelch repeat and BTB (POZ) domain containing 4,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.207,10,-0.6,3.59,-0.5,3.04,-3.04,0.293,0,0,-1.7,0.3
ENSMUSG00000042524,SUN2,Sad1 and UNC84 domain containing 2,"nuclear chromosome, telomeric region|nuclear chromosome, telomeric region|condensed nuclear chromosome|condensed nuclear chromosome|cell|nucleus|nuclear envelope|nuclear envelope|nuclear inner membrane|endosome|membrane|integral component of membrane|nuclear membrane|SUN-KASH complex|",nuclear envelope organization|positive regulation of cell migration|nuclear migration along microfilament|centrosome localization|cytoskeletal anchoring at nuclear membrane|nuclear matrix anchoring at nuclear membrane|,protein binding|lamin binding|identical protein binding|,10,-0.2,0.228,10,-0.5,3.13,-0.5,3.03,-3.03,0.294,0,0,-1.5,0.9
ENSMUSG00000050973,GDPGP1,GDP-D-glucose phosphorylase 1,cellular_component|cytoplasm|,glucose metabolic process|,nucleotide binding|guanyl-nucleotide exchange factor activity|transferase activity|nucleotidyltransferase activity|hydrolase activity|GDP-D-glucose phosphorylase activity|,10,-1.3,2.61,10,0.5,3.63,-0.6,3.01,-3.01,0.296,0,0,-2,0.9
ENSMUSG00000032127,VPS11,vacuolar protein sorting 11 (yeast),lysosome|lysosomal membrane|endosome|early endosome|actin filament|membrane|endocytic vesicle|HOPS complex|cytoplasmic vesicle|,transport|intracellular protein transport|biological_process|protein transport|vesicle-mediated transport|,nucleotide binding|protein binding|zinc ion binding|metal ion binding|,10,0.6,2,8,0.3,1.48,0.5,3.01,3.01,0.296,0,0,-0.5,1.6
ENSMUSG00000029198,GRPEL1,"GrpE-like 1, mitochondrial",mitochondrion|mitochondrion|mitochondrial matrix|,protein folding|,adenyl-nucleotide exchange factor activity|protein homodimerization activity|unfolded protein binding|chaperone binding|,9,-0.9,3.02,6,0.7,1.87,-0.7,3.01,-3.01,0.296,0,0,-2,1.1
ENSMUSG00000015837,SQSTM1,sequestosome 1,pre-autophagosomal structure|cytoplasmic mRNA processing body|nucleus|cytoplasm|cytoplasm|lysosome|endosome|autophagic vacuole|endoplasmic reticulum|inclusion body|aggresome|PML body|cytoplasmic vesicle|extracellular vesicular exosome|,positive regulation of protein phosphorylation|immune system process|autophagy|apoptotic process|positive regulation of macroautophagy|cell differentiation|regulation of I-kappaB kinase/NF-kappaB signaling|protein heterooligomerization|regulation of RNA biosynthetic process|,transcription cofactor activity|protein kinase C binding|protein binding|zinc ion binding|protein kinase binding|SH2 domain binding|identical protein binding|identical protein binding|protein homodimerization activity|ubiquitin binding|metal ion binding|K63-linked polyubiquitin binding|,10,1.4,3.03,10,0.5,2.98,0.7,3,3,0.297,0,0,-0.5,2
ENSMUSG00000029922,MKRN1,"makorin, ring finger protein, 1",None,protein polyubiquitination|,"chromatin binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,0.1,0.02,10,-0.6,5.35,-0.5,2.99,-2.99,0.297,0,0,-1.7,0.4
ENSMUSG00000001366,FBXO9,f-box protein 9,cytoplasm|SCF ubiquitin ligase complex|,protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|regulation of TOR signaling|innate immune response|fat cell differentiation|fat cell differentiation|,molecular_function|,10,0.4,3.16,10,0.1,0.272,0.3,2.97,2.97,0.299,0,0,-0.9,1.6
ENSMUSG00000033285,WDR3,WD repeat domain 3,nucleus|nucleolus|nuclear membrane|,biological_process|,poly(A) RNA binding|,9,-0.5,3.43,10,0,0,-0.5,2.97,-2.97,0.299,0,0,-1.7,0.6
ENSMUSG00000005804,BLOC1S6,"biogenesis of lysosomal organelles complex-1, subunit 6, pallidin",intracellular|cell|cytoplasm|endosome|membrane|extrinsic component of membrane|transport vesicle|BLOC-1 complex|BLOC-1 complex|SNARE complex|,vesicle docking involved in exocytosis|vesicle fusion|blood coagulation|anterograde axon cargo transport|melanocyte differentiation|neuron projection development|melanosome transport|positive regulation of natural killer cell activation|secretion of lysosomal enzymes|endosome to melanosome transport|pigmentation|anterograde synaptic vesicle transport|positive regulation of pigment cell differentiation|membrane fusion|,protein binding|identical protein binding|protein homodimerization activity|actin filament binding|,10,0.2,0.518,10,0.8,3.08,0.6,2.94,2.94,0.302,0,0,-0.2,1.8
ENSMUSG00000030270,CPNE9,copine family member IX,extracellular space|,biological_process|,molecular_function|,10,-0.2,0.223,10,-0.5,3.36,-0.3,2.93,-2.93,0.302,0,0,-1.6,0.3
ENSMUSG00000020908,MYH3,"myosin, heavy polypeptide 3, skeletal muscle, embryonic",cytoplasm|myosin complex|myosin filament|contractile fiber|extracellular vesicular exosome|,skeletal muscle contraction|ATP catabolic process|,microfilament motor activity|nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|actin filament binding|,10,-0.5,3.82,10,0.3,1.22,-0.4,2.91,-2.91,0.304,0,0,-1.3,1.4
ENSMUSG00000022890,ATP5J,"ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F","mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial proton-transporting ATP synthase complex|membrane|proton-transporting ATP synthase complex, coupling factor F(o)|",ATP catabolic process|transport|ion transport|ATP synthesis coupled proton transport|proton transport|ATP metabolic process|,hydrogen ion transmembrane transporter activity|ATPase activity|,10,-0.8,5.74,10,0.6,2.36,-0.8,2.91,-2.91,0.304,0,0,-1.9,1
ENSMUSG00000053113,SOCS3,suppressor of cytokine signaling 3,cytoplasm|,regulation of protein phosphorylation|signal transduction|JAK-STAT cascade|negative regulation of signal transduction|intracellular signal transduction|regulation of growth|negative regulation of apoptotic process|regulation of cell differentiation|regulation of cell differentiation|positive regulation of cell differentiation|positive regulation of cell differentiation|negative regulation of insulin receptor signaling pathway|branching involved in labyrinthine layer morphogenesis|placenta blood vessel development|trophoblast giant cell differentiation|trophoblast giant cell differentiation|spongiotrophoblast differentiation|spongiotrophoblast differentiation|,protein binding|,10,0.3,0.638,10,-0.5,2.77,-0.4,2.89,-2.89,0.306,0,0,-1.6,0.6
ENSMUSG00000040365,TRIM41,tripartite motif-containing 41,intracellular|nucleus|nucleolus|cytoplasm|,biological_process|,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-1.2,2.35,10,-0.2,1.2,-0.2,2.86,-2.86,0.308,0,0,-1.9,0.1
ENSMUSG00000033124,ATG9A,autophagy related 9A,pre-autophagosomal structure|pre-autophagosomal structure|cytoplasm|endosome|late endosome|autophagic vacuole|Golgi apparatus|trans-Golgi network|membrane|membrane|integral component of membrane|cytoplasmic vesicle|recycling endosome|,autophagic vacuole assembly|autophagic vacuole assembly|autophagic vacuole assembly|autophagic vacuole assembly|mitochondrion degradation|transport|autophagy|protein transport|protein localization to Golgi apparatus|protein localization to pre-autophagosomal structure|piecemeal microautophagy of nucleus|late nucleophagy|innate immune response|,molecular_function|,10,-0.5,2.61,10,1,3.58,-0.4,2.85,-2.85,0.309,0,0,-1.1,1.9
ENSMUSG00000027983,CYP2U1,"cytochrome P450, family 2, subfamily u, polypeptide 1",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|heme binding|metal ion binding|aromatase activity|",9,1,0.863,9,0.8,2.36,0.9,2.85,2.85,0.309,0,0,-0.2,2
ENSMUSG00000040415,DTX3,deltex 3 homolog (Drosophila),cellular_component|cytoplasm|,Notch signaling pathway|Notch signaling pathway|,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.518,10,0.6,4.51,0.6,2.84,2.84,0.309,0,0,-0.6,1.7
ENSMUSG00000068040,TM9SF4,transmembrane 9 superfamily protein member 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-1.1,1.54,10,-0.6,2.18,-0.7,2.83,-2.83,0.31,0,0,-1.9,0.5
ENSMUSG00000021194,CHGA,chromogranin A,extracellular region|extracellular space|membrane|secretory granule|cytoplasmic vesicle|chromaffin granule|perinuclear region of cytoplasm|,regulation of the force of heart contraction|organelle organization|positive regulation of cAMP metabolic process|negative regulation of vasodilation|positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|negative regulation of neuron death|,protein binding|,10,1.1,0.736,10,-1.6,6.17,-1.6,2.83,-2.83,0.31,0,0,-3,0.6
ENSMUSG00000020260,POFUT2,protein O-fucosyltransferase 2,endoplasmic reticulum|Golgi apparatus|,mesoderm formation|carbohydrate metabolic process|fucose metabolic process|regulation of gene expression|regulation of epithelial to mesenchymal transition|fucosylation|fucosylation|protein O-linked fucosylation|regulation of secretion|,"fucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|peptide-O-fucosyltransferase activity|",10,0.5,4.05,10,0.1,0.0116,0.4,2.81,2.81,0.312,0,0,-1,1.4
ENSMUSG00000020840,BLMH,bleomycin hydrolase,nucleus|cytoplasm|extracellular vesicular exosome|,proteolysis|response to toxic substance|response to drug|,cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,9,0.2,0.811,9,0.5,2.68,0.3,2.8,2.8,0.313,0,0,-0.4,1.6
ENSMUSG00000034164,EMID1,EMI domain containing 1,extracellular region|proteinaceous extracellular matrix|collagen trimer|endoplasmic reticulum|Golgi apparatus|,biological_process|,protein binding|,10,0.6,2.46,9,0.3,0.934,0.3,2.8,2.8,0.313,0,0,-0.5,1.5
ENSMUSG00000004473,CLEC11A,"C-type lectin domain family 11, member a",extracellular region|extracellular space|cytoplasm|,positive regulation of cell proliferation|,growth factor activity|carbohydrate binding|,10,0.4,2.65,10,0.2,0.755,0.4,2.79,2.79,0.314,0,0,-0.5,1.5
ENSMUSG00000025139,TOLLIP,toll interacting protein,cytoplasm|nuclear body|perinuclear region of cytoplasm|extracellular vesicular exosome|,immune system process|inflammatory response|signal transduction|phosphorylation|positive regulation of protein sumoylation|protein localization to endosome|innate immune response|,"interleukin-1, Type I receptor binding|protein binding|kinase binding|ubiquitin conjugating enzyme binding|ubiquitin protein ligase binding|SUMO binding|Toll-like receptor binding|",9,0,0,9,-0.5,4.11,-0.4,2.79,-2.79,0.314,0,0,-1.7,0.6
ENSMUSG00000040850,PSME4,"proteasome (prosome, macropain) activator subunit 4",proteasome complex|nucleus|nucleus|cytoplasm|cytosol|spermatoproteasome complex|,"DNA repair|cellular response to DNA damage stimulus|multicellular organismal development|spermatogenesis|proteasomal ubiquitin-independent protein catabolic process|positive regulation of peptidase activity|cell differentiation|spermatogenesis, exchange of chromosomal proteins|",peptidase activator activity|lysine-acetylated histone binding|,10,-0.7,3.3,10,0.7,2.88,-0.7,2.77,-2.77,0.315,0,0,-1.6,1.4
ENSMUSG00000027243,HARBI1,harbinger transposase derived 1,nucleus|cytoplasm|centrosome|,biological_process|,molecular_function|nuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,-0.3,0.945,10,1.3,4.68,-0.5,2.77,-2.77,0.315,0,0,-1.4,2
ENSMUSG00000026580,SELP,"selectin, platelet",extracellular space|nucleus|cytoplasm|external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|platelet alpha granule membrane|,positive regulation of leukocyte migration|positive regulation of leukocyte migration|regulation of cellular extravasation|inflammatory response|inflammatory response|cell adhesion|heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|leukocyte cell-cell adhesion|positive regulation of platelet activation|positive regulation of phosphatidylinositol 3-kinase signaling|single organismal cell-cell adhesion|regulation of integrin activation|positive regulation of cell adhesion|blood vessel morphogenesis|leukocyte migration|leukocyte migration|leukocyte tethering or rolling|cellular response to interleukin-6|,lipopolysaccharide binding|glycoprotein binding|protein binding|heparin binding|carbohydrate binding|sialic acid binding|sialic acid binding|fucose binding|calcium-dependent protein binding|oligosaccharide binding|,10,-1.6,4.65,10,1.2,5.28,0.3,2.77,2.77,0.315,0,0,-2.4,2
ENSMUSG00000025572,TMC6,transmembrane channel-like gene family 6,cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|nuclear membrane|extracellular vesicular exosome|,transport|ion transport|biological_process|,molecular_function|,10,0.2,0.914,10,0.3,2.23,0.3,2.76,2.76,0.316,0,0,-0.6,1.5
ENSMUSG00000033379,ATP6V0B,"ATPase, H+ transporting, lysosomal V0 subunit B","endosome|vacuole|membrane|integral component of membrane|vacuolar proton-transporting V-type ATPase complex|proton-transporting two-sector ATPase complex, proton-transporting domain|proton-transporting V-type ATPase, V0 domain|",ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrogen ion transmembrane transporter activity|",6,-1.1,3.53,5,0.4,0.777,-1,2.76,-2.76,0.316,0,0,-2,0.6
ENSMUSG00000036880,ACAA2,acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase),mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial matrix|extracellular vesicular exosome|,acetyl-CoA metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|metabolic process|cellular response to hypoxia|negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|negative regulation of mitochondrial membrane permeability involved in apoptotic process|,"catalytic activity|acetyl-CoA C-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|poly(A) RNA binding|",10,1.1,2.14,10,0.3,2.12,0.5,2.74,2.74,0.317,0,0,-0.3,1.9
ENSMUSG00000069268,HIST1H2BF,"histone cluster 1, H2bf",extracellular space|nucleus|extracellular vesicular exosome|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,molecular_function|,3,1.2,4.4,3,-0.3,0.326,1.2,2.72,2.72,0.319,0,0,-1,2
ENSMUSG00000024983,VTI1A,vesicle transport through interaction with t-SNAREs 1A,Golgi apparatus|synaptic vesicle|membrane|integral component of membrane|clathrin-coated vesicle|SNARE complex|neuronal cell body|neuron projection terminus|perinuclear region of cytoplasm|,"transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|retrograde transport, endosome to Golgi|vesicle fusion with Golgi apparatus|",SNAP receptor activity|,10,-0.5,1.23,10,-0.4,1.69,-0.4,2.72,-2.72,0.319,0,0,-1.6,0.4
ENSMUSG00000034177,RNF43,ring finger protein 43,nucleus|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,Wnt signaling pathway|protein ubiquitination|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|Wnt receptor catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|stem cell proliferation|,"ubiquitin-protein transferase activity|frizzled binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,3.38,10,0.2,1.03,-0.4,2.7,-2.7,0.321,0,0,-1.4,0.9
ENSMUSG00000035021,BAZ1A,bromodomain adjacent to zinc finger domain 1A,nuclear chromosome|nucleus|CHRAC|,"DNA-dependent DNA replication|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|",protein binding|zinc ion binding|metal ion binding|,9,0.7,3.99,9,0,0,0.4,2.7,2.7,0.321,0,0,-0.3,1.8
ENSMUSG00000038611,PHRF1,PHD and ring finger domains 1,nucleus|membrane|,transcription from RNA polymerase II promoter|mRNA processing|intracellular signal transduction|,zinc ion binding|protein domain specific binding|metal ion binding|RNA polymerase binding|,9,0.2,1.11,9,-0.6,5.03,-0.4,2.7,-2.7,0.321,0,0,-1.8,0.6
ENSMUSG00000051727,KCTD14,potassium channel tetramerisation domain containing 14,cellular_component|,transport|ion transport|biological_process|,molecular_function|,10,-0.6,2.04,10,-0.3,1.08,-0.4,2.69,-2.69,0.322,0,0,-1.6,0.7
ENSMUSG00000021898,ASB14,ankyrin repeat and SOCS box-containing 14,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0.3,1.8,10,0.2,1.11,0.2,2.67,2.67,0.323,0,0,-0.8,1.6
ENSMUSG00000008226,SCRN3,secernin 3,cellular_component|,proteolysis|biological_process|,molecular_function|dipeptidase activity|,10,0.6,2.21,10,-0.6,1.88,-0.5,2.66,-2.66,0.324,0,0,-1.6,1.1
ENSMUSG00000034371,DAK,dihydroxyacetone kinase 2 homolog (yeast),nucleus|extracellular vesicular exosome|,glycerol metabolic process|metabolic process|phosphorylation|cellular carbohydrate metabolic process|regulation of innate immune response|carbohydrate phosphorylation|,nucleotide binding|catalytic activity|glycerone kinase activity|protein binding|ATP binding|kinase activity|transferase activity|lyase activity|FAD-AMP lyase (cyclizing) activity|metal ion binding|triokinase activity|,10,0.4,1.48,10,0.7,1.88,0.5,2.65,2.65,0.324,0,0,-0.4,1.7
ENSMUSG00000019952,POC1B,POC1 centriolar protein homolog B (Chlamydomonas),spindle pole|cytoplasm|centrosome|centriole|cytoskeleton|ciliary basal body|cell projection|,cell proliferation|cell projection organization|cilium assembly|,molecular_function|,10,-0.2,0.165,10,1,5.13,0.9,2.65,2.65,0.324,0,0,-0.5,2
ENSMUSG00000055866,PER2,period circadian clock 2,nucleus|nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|circadian rhythm|negative regulation of transcription, DNA-templated|",transcription factor binding transcription factor activity|protein binding|,10,0,0,10,-1.5,5.87,-1.5,2.61,-2.61,0.328,0,0,-2.9,0
ENSMUSG00000037434,SLC30A1,"solute carrier family 30 (zinc transporter), member 1",cytoplasm|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|T-tubule|nuclear membrane|,in utero embryonic development|transport|ion transport|cation transport|zinc ion transport|zinc ion transport|cellular calcium ion homeostasis|cellular zinc ion homeostasis|cellular zinc ion homeostasis|negative regulation of neurotransmitter secretion|transmembrane transport|calcium ion import|cadmium ion transmembrane transport|zinc ion transmembrane transport|negative regulation of zinc ion transmembrane import|detoxification of cadmium ion|negative regulation of calcium ion import|,zinc ion transmembrane transporter activity|cation transmembrane transporter activity|calcium channel inhibitor activity|calcium channel inhibitor activity|,10,0.5,3.44,10,0.1,0.164,0.5,2.61,2.61,0.328,0,0,-0.5,1.6
ENSMUSG00000039717,RALYL,RALY RNA binding protein-like,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0,0,10,-0.7,3.27,-0.4,2.6,-2.6,0.329,0,0,-1.7,0.2
ENSMUSG00000046873,MBTPS2,"membrane-bound transcription factor peptidase, site 2",cytoplasm|,None,None,8,-1.2,3.33,6,1,2.41,0.5,2.6,2.6,0.329,0,0,-1.9,1.5
ENSMUSG00000039206,DAGLB,"diacylglycerol lipase, beta",lysosomal membrane|plasma membrane|membrane|integral component of membrane|,lipid metabolic process|neuroblast proliferation|lipid catabolic process|arachidonic acid metabolic process|arachidonic acid metabolic process|neurogenesis|neurotransmitter biosynthetic process|,"phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|metal ion binding|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-1.3,5.77,10,0.3,1.05,-0.2,2.59,-2.59,0.33,0,0,-2,0.2
ENSMUSG00000057003,MYH4,"myosin, heavy polypeptide 4, skeletal muscle",cytoplasm|myosin complex|myofibril|myosin filament|,muscle contraction|response to activity|,nucleotide binding|double-stranded RNA binding|motor activity|actin binding|calmodulin binding|ATP binding|,10,0,0,10,1.2,5.57,1.2,2.59,2.59,0.33,0,0,-0.1,2
ENSMUSG00000038910,PLCL2,phospholipase C-like 2,cytoplasm|,"B cell proliferation involved in immune response|B-1a B cell differentiation|lipid metabolic process|signal transduction|gamma-aminobutyric acid signaling pathway|regulation of synaptic transmission, GABAergic|regulation of peptidyl-serine phosphorylation|intracellular signal transduction|negative regulation of B cell receptor signaling pathway|positive regulation of receptor binding|",phosphatidylinositol phospholipase C activity|signal transducer activity|calcium ion binding|phosphoric diester hydrolase activity|GABA receptor binding|,10,0.3,1.2,10,0.3,1.57,0.3,2.58,2.58,0.331,0,0,-0.5,1.5
ENSMUSG00000020900,MYH10,"myosin, heavy polypeptide 10, non-muscle",stress fiber|stress fiber|stress fiber|nucleus|cytoplasm|cytoplasm|spindle|plasma membrane|cell cortex|cell cortex|myosin complex|myosin II complex|myosin II complex|axon|growth cone|midbody|neuromuscular junction|cleavage furrow|actomyosin|cell projection|neuron projection|neuronal cell body|dendritic spine|myosin II filament|,"mitotic cytokinesis|mitotic cytokinesis|in utero embryonic development|neuron migration|plasma membrane repair|ATP catabolic process|exocytosis|substrate-dependent cell migration, cell extension|nuclear migration|cell adhesion|axonogenesis|axon guidance|brain development|adult heart development|cell proliferation|regulation of cell shape|fourth ventricle development|lateral ventricle development|third ventricle development|cerebellar Purkinje cell layer development|actin cytoskeleton organization|actin filament-based movement|myofibril assembly|actomyosin structure organization|neuron projection development|neuromuscular process controlling balance|cardiac myofibril assembly|ventricular cardiac muscle cell development|retina development in camera-type eye|",microfilament motor activity|nucleotide binding|motor activity|actin binding|protein binding|calmodulin binding|ATP binding|actin-dependent ATPase activity|ADP binding|actin filament binding|,10,0,0,10,-0.6,4.56,-0.5,2.56,-2.56,0.332,0,0,-1.7,0.6
ENSMUSG00000057465,SAA2,serum amyloid A 2,extracellular region|high-density lipoprotein particle|extracellular vesicular exosome|,acute-phase response|,G-protein coupled receptor binding|protein binding|,10,-0.7,2.71,10,-0.2,1.04,-0.5,2.52,-2.52,0.336,0,0,-1.7,0.4
ENSMUSG00000006412,PFDN2,prefoldin 2,nucleus|nucleolus|cytoplasm|mitochondrion|Golgi apparatus|cytosol|prefoldin complex|extracellular vesicular exosome|,protein folding|,molecular_function|unfolded protein binding|,8,0.9,3.73,9,0.2,0.283,0.5,2.5,2.5,0.338,0,0,-1.2,1.8
ENSMUSG00000038451,SPSB2,splA/ryanodine receptor domain and SOCS box containing 2,cytoplasm|,intracellular signal transduction|,protein binding|,10,0.3,0.902,10,0.5,1.91,0.4,2.5,2.5,0.338,0,0,-0.2,1.8
ENSMUSG00000021037,AHSA1,"AHA1, activator of heat shock protein ATPase 1",cytoplasm|endoplasmic reticulum|extracellular vesicular exosome|,response to stress|positive regulation of ATPase activity|,ATPase activator activity|chaperone binding|,10,-0.4,1.23,10,-0.3,1.53,-0.3,2.47,-2.47,0.341,0,0,-1.7,0.7
ENSMUSG00000020593,LPIN1,lipin 1,nucleus|transcription factor complex|cytoplasm|mitochondrion|mitochondrial outer membrane|endoplasmic reticulum|membrane|nuclear membrane|,"negative regulation of transcription from RNA polymerase II promoter|mitochondrial fission|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|lipid metabolic process|triglyceride mobilization|fatty acid catabolic process|dephosphorylation|triglyceride biosynthetic process|positive regulation of histone deacetylation|ruffle organization|actin cytoskeleton reorganization|cellular response to insulin stimulus|cellular response to insulin stimulus|fat cell differentiation|regulation of fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription factor binding|transcription coactivator activity|protein binding|phosphatidate phosphatase activity|hydrolase activity|histone deacetylase binding|peroxisome proliferator activated receptor binding|,10,0.7,4.07,10,0.1,0.131,0.6,2.45,2.45,0.343,0,0,-0.1,1.9
ENSMUSG00000056162,CNDP1,carnosine dipeptidase 1 (metallopeptidase M20 family),cytosol|,proteolysis|metabolic process|,carboxypeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|dipeptidase activity|tripeptidase activity|metal ion binding|,10,-0.4,0.708,10,-0.6,1.98,-0.5,2.44,-2.44,0.344,0,0,-1.7,0.8
ENSMUSG00000028243,UBXN2B,UBX domain protein 2B,cellular_component|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|,biological_process|,molecular_function|,10,-0.3,1.06,10,-0.3,1.55,-0.3,2.43,-2.43,0.345,0,0,-1.4,1
ENSMUSG00000039887,ALG14,asparagine-linked glycosylation 14,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.7,3.09,9,0.4,2,0.5,2.43,2.43,0.345,0,0,-1.6,1.5
ENSMUSG00000026411,TMEM9,transmembrane protein 9,lysosome|endosome|late endosome|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,-0.5,3.86,10,0,0,-0.3,2.42,-2.42,0.346,0,0,-1.6,0.7
ENSMUSG00000028064,SEMA4A,"sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A",plasma membrane|membrane|integral component of membrane|,angiogenesis|T cell differentiation involved in immune response|immune system process|multicellular organismal development|nervous system development|axonogenesis|regulation of cell shape|regulation of endothelial cell migration|negative regulation of angiogenesis|cell differentiation|T-helper 1 cell differentiation|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|,receptor activity|,10,-0.3,1.56,10,-0.3,1.02,-0.3,2.4,-2.4,0.348,0,0,-1.3,1.3
ENSMUSG00000021706,ZFYVE16,"zinc finger, FYVE domain containing 16",cytoplasm|endosome|early endosome|membrane|intracellular membrane-bounded organelle|,protein targeting to lysosome|endosomal transport|,"1-phosphatidylinositol binding|phosphatidylinositol-3,4,5-trisphosphate binding|protein transporter activity|metal ion binding|",10,-0.6,3.65,10,-0.1,0.322,-0.4,2.4,-2.4,0.348,0,0,-1.7,0.3
ENSMUSG00000031320,RPS4X,"ribosomal protein S4, X-linked",intracellular|nucleus|cytoplasm|ribosome|polysome|small ribosomal subunit|membrane|ribonucleoprotein complex|,translation|multicellular organismal development|,RNA binding|structural constituent of ribosome|rRNA binding|,5,1.1,4.06,5,-0.7,3.04,1,2.38,2.38,0.35,0,0,-1.4,2
ENSMUSG00000034533,SCN10A,"sodium channel, voltage-gated, type X, alpha",voltage-gated sodium channel complex|plasma membrane|membrane|integral component of membrane|axon|C-fiber|extracellular vesicular exosome|clathrin complex|,regulation of heart rate|transport|ion transport|sodium ion transport|sodium ion transport|neuronal action potential|sensory perception of pain|regulation of ion transmembrane transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|transmembrane transport|regulation of cardiac muscle contraction|regulation of atrial cardiac muscle cell membrane depolarization|regulation of atrial cardiac muscle cell membrane depolarization|cardiac conduction|membrane depolarization during action potential|AV node cell to bundle of His cell communication|bundle of His cell to Purkinje myocyte communication|,ion channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|sodium channel activity|,10,-0.3,3.05,10,0,0,-0.3,2.38,-2.38,0.35,0,0,-1.5,0.5
ENSMUSG00000074001,KLHL40,kelch-like 40,cellular_component|cytoplasm|,multicellular organismal development|biological_process|,molecular_function|,10,0.2,0.316,10,0.5,2.59,0.4,2.37,2.37,0.351,0,0,-0.3,1.7
ENSMUSG00000031896,CTRL,chymotrypsin-like,None,proteolysis|proteolysis|,peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.5,4.49,10,0.1,0.0182,-0.3,2.35,-2.35,0.353,0,0,-1.5,0.6
ENSMUSG00000027134,LPCAT4,lysophosphatidylcholine acyltransferase 4,endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|phospholipid metabolic process|metabolic process|phospholipid biosynthetic process|,"transferase activity|transferase activity, transferring acyl groups|1-alkenylglycerophosphoethanolamine O-acyltransferase activity|1-acylglycerophosphocholine O-acyltransferase activity|1-alkylglycerophosphocholine O-acetyltransferase activity|lysophospholipid acyltransferase activity|",10,1.1,1.32,10,-0.9,2.51,-0.5,2.34,-2.34,0.354,0,0,-1.7,1.4
ENSMUSG00000071172,SRSF3,serine/arginine-rich splicing factor 3,nucleus|cytoplasm|nuclear speck|,mRNA processing|transport|insulin receptor signaling pathway|RNA splicing|mRNA transport|,nucleotide binding|nucleic acid binding|RNA binding|phospholipase binding|poly(A) RNA binding|,4,0.2,0.062,5,-0.4,2.79,-0.4,2.34,-2.34,0.354,0,0,-2,1
ENSMUSG00000024360,ETF1,eukaryotic translation termination factor 1,cellular_component|cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|translation|translational termination|protein methylation|viral process|","translation release factor activity|translation release factor activity, codon specific|poly(A) RNA binding|",9,0.5,2.84,9,-0.2,0.291,0.5,2.34,2.34,0.354,0,0,-0.8,1.9
ENSMUSG00000030894,TPP1,tripeptidyl peptidase I,mitochondrion|lysosome|lysosome|extracellular vesicular exosome|,proteolysis|proteolysis|lysosome organization|nervous system development|nervous system development|peptide catabolic process|peptide catabolic process|bone resorption|bone resorption|neuromuscular process controlling balance|,endopeptidase activity|endopeptidase activity|serine-type endopeptidase activity|protein binding|peptidase activity|peptidase activity|serine-type peptidase activity|serine-type peptidase activity|tripeptidyl-peptidase activity|tripeptidyl-peptidase activity|hydrolase activity|peptide binding|metal ion binding|,10,0,0,10,1,5.17,0.9,2.34,2.34,0.354,0,0,-0.1,2
ENSMUSG00000020311,ERLEC1,endoplasmic reticulum lectin 1,endoplasmic reticulum|endoplasmic reticulum lumen|,ER-associated ubiquitin-dependent protein catabolic process|,glycoprotein binding|,10,0,0,10,-0.4,3.64,-0.3,2.33,-2.33,0.355,0,0,-1.5,0.8
ENSMUSG00000040387,KLHL32,kelch-like 32,cellular_component|,biological_process|,molecular_function|,10,-0.6,1.64,10,-0.3,1.36,-0.3,2.31,-2.31,0.357,0,0,-1.7,0.3
ENSMUSG00000048787,DCUN1D3,"DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)",perinuclear region of cytoplasm|,response to UV-C|response to gamma radiation|negative regulation of cell growth|positive regulation of apoptotic process|,molecular_function|,10,0,0,10,0.4,3.46,0.3,2.31,2.31,0.357,0,0,-0.6,1.5
ENSMUSG00000047810,CCDC88B,coiled-coil domain containing 88B,membrane|,biological_process|,molecular_function|,10,-0.1,0.227,10,-0.5,3.47,-0.4,2.28,-2.28,0.36,0,0,-1.7,0.6
ENSMUSG00000027679,DNAJC19,"DnaJ (Hsp40) homolog, subfamily C, member 19",mitochondrion|mitochondrion|,visual perception|genitalia development|,molecular_function|,10,0,0,10,1.2,4.21,0.2,2.28,2.28,0.36,0,0,-0.3,2
ENSMUSG00000047824,PYGO2,pygopus 2,nucleus|nucleus|,in utero embryonic development|kidney development|lens development in camera-type eye|spermatid development|spermatid nucleus differentiation|brain development|post-embryonic development|post-embryonic development|Wnt signaling pathway|Wnt signaling pathway|mammary gland development|regulation of mammary gland epithelial cell proliferation|regulation of histone acetylation|positive regulation of chromatin binding|developmental growth|regulation of catalytic activity|regulation of histone H3-K4 methylation|palate development|canonical Wnt signaling pathway|,chromatin binding|protein binding|histone acetyltransferase regulator activity|histone binding|histone binding|metal ion binding|,10,-0.3,1.6,10,-0.4,0.947,-0.4,2.28,-2.28,0.36,0,0,-1.6,0.5
ENSMUSG00000029634,RNF6,ring finger protein (C3H2C3 type) 6,nucleus|cytoplasm|cytoplasm|PML body|axon|nuclear membrane|cell projection|intracellular membrane-bounded organelle|,"regulation of transcription, DNA-templated|ubiquitin-dependent protein catabolic process|protein ubiquitination|negative regulation of axon extension|negative regulation of axon extension|protein K27-linked ubiquitination|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|regulation of androgen receptor signaling pathway|protein K48-linked ubiquitination|protein K6-linked ubiquitination|","DNA binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|androgen receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,0.773,10,-0.3,1.61,-0.3,2.22,-2.22,0.366,0,0,-1.6,1.5
ENSMUSG00000001555,FKBP10,FK506 binding protein 10,endoplasmic reticulum|endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|calcium ion binding|protein binding|FK506 binding|isomerase activity|metal ion binding|,10,0.1,0.0115,10,-0.5,3.81,-0.5,2.21,-2.21,0.367,0,0,-1.7,0.4
ENSMUSG00000040749,SIAH1B,seven in absentia 1B,nucleus|cytoplasm|,ubiquitin-dependent protein catabolic process|multicellular organismal development|protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,1.81,10,-0.2,0.717,-0.3,2.19,-2.19,0.369,0,0,-1.6,0.9
ENSMUSG00000039108,LSM14B,"LSM14 homolog B (SCD6, S. cerevisiae)",cellular_component|ribonucleoprotein complex|,regulation of translation|multicellular organismal development|biological_process|,poly(A) RNA binding|,10,0.5,2.87,10,0,0,0.4,2.18,2.18,0.37,0,0,-1.6,1.6
ENSMUSG00000017288,VPS53,vacuolar protein sorting 53 (yeast),GARP complex|endosome|Golgi apparatus|membrane|,transport|protein transport|,None,10,0.3,0.763,10,0.8,2.77,0.7,2.17,2.17,0.371,0,0,-0.8,1.9
ENSMUSG00000020258,GLYCTK,glycerate kinase,cytoplasm|mitochondrion|,protein phosphorylation|phosphorylation|,nucleotide binding|ATP binding|glycerate kinase activity|kinase activity|transferase activity|,10,0.2,0.816,10,-0.8,4.97,-0.7,2.17,-2.17,0.371,0,0,-2,0.5
ENSMUSG00000020482,CCDC117,coiled-coil domain containing 117,cellular_component|,biological_process|,molecular_function|,10,0.2,0.773,10,0.3,1.64,0.2,2.15,2.15,0.374,0,0,-0.9,1.4
ENSMUSG00000025283,SAT1,spermidine/spermine N1-acetyl transferase 1,intracellular|cytoplasm|cytosol|,polyamine metabolic process|polyamine catabolic process|spermidine acetylation|regulation of cell proliferation|spermine catabolic process|,"diamine N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|spermidine binding|",10,-0.3,0.181,10,-0.6,2.5,-0.4,2.15,-2.15,0.374,0,0,-1.7,1
ENSMUSG00000028397,KDM4C,lysine (K)-specific demethylase 4C,nuclear chromatin|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|positive regulation of cell proliferation|chromatin modification|histone H3-K9 demethylation|oxidation-reduction process|","sulfonate dioxygenase activity|zinc ion binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|enzyme binding|enzyme binding|histone demethylase activity (H3-K9 specific)|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|androgen receptor binding|androgen receptor binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.2,0.939,10,-0.4,1.55,-0.3,2.14,-2.14,0.375,0,0,-1.5,0.7
ENSMUSG00000002845,TMEM39A,transmembrane protein 39a,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.244,10,-0.3,2.61,-0.3,2.14,-2.14,0.375,0,0,-1.6,0.5
ENSMUSG00000027884,CLCC1,chloride channel CLIC-like 1,nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,chloride transport|chloride transmembrane transport|,chloride channel activity|,10,1.5,4.92,10,-1.9,4.08,0.3,2.14,2.14,0.375,0,0,-2.6,3
ENSMUSG00000034235,USP54,ubiquitin specific peptidase 54,cellular_component|,ubiquitin-dependent protein catabolic process|biological_process|,molecular_function|ubiquitinyl hydrolase activity|,10,0,0,10,1.1,3.77,0.4,2.14,2.14,0.375,0,0,-0.2,2
ENSMUSG00000028559,OSBPL9,oxysterol binding protein-like 9,cytoplasm|Golgi apparatus|,transport|lipid transport|biological_process|,molecular_function|,10,0.4,2.43,10,0,0,0.4,2.14,2.14,0.375,0,0,-0.5,1.8
ENSMUSG00000020642,RNF144A,ring finger protein 144A,Golgi apparatus|membrane|integral component of membrane|,biological_process|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.6,2.56,10,0.2,0.0268,0.3,2.13,2.13,0.376,0,0,-0.4,1.7
ENSMUSG00000034614,PIK3IP1,phosphoinositide-3-kinase interacting protein 1,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,negative regulation of phosphatidylinositol 3-kinase signaling|negative regulation of phosphatidylinositol 3-kinase signaling|negative regulation of phosphatidylinositol 3-kinase activity|negative regulation of phosphatidylinositol 3-kinase activity|,phosphatidylinositol 3-kinase catalytic subunit binding|,10,0.4,3.82,10,-0.3,0.648,0.3,2.13,2.13,0.376,0,0,-0.7,1.8
ENSMUSG00000040464,GTPBP10,GTP-binding protein 10 (putative),nucleus|mitochondrion|,biological_process|ribosome biogenesis|,nucleotide binding|magnesium ion binding|GTPase activity|GTP binding|poly(A) RNA binding|,10,-0.2,1.28,10,-0.3,1.1,-0.3,2.1,-2.1,0.379,0,0,-1.7,0.7
ENSMUSG00000005501,USP40,ubiquitin specific peptidase 40,cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,-0.5,4.54,10,0,0,-0.4,2.09,-2.09,0.38,0,0,-1.6,0.5
ENSMUSG00000036990,OTUD4,OTU domain containing 4,cellular_component|,proteolysis|protein K48-linked deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|poly(A) RNA binding|,10,0.2,0.957,10,0.3,1.48,0.3,2.09,2.09,0.38,0,0,-0.6,1.5
ENSMUSG00000051367,SIX1,sine oculis-related homeobox 1,nucleus|nucleus|transcription factor complex|transcription factor complex|nucleolus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|ureteric bud development|ureteric bud development|branching involved in ureteric bud morphogenesis|organ induction|kidney development|outflow tract morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|multicellular organismal development|pattern specification process|pattern specification process|skeletal muscle tissue development|sensory perception of sound|regulation of synaptic growth at neuromuscular junction|regulation of gene expression|facial nerve morphogenesis|epithelial cell differentiation|thyroid gland development|regulation of protein localization|protein localization to nucleus|aorta morphogenesis|inner ear morphogenesis|middle ear morphogenesis|negative regulation of neuron apoptotic process|regulation of neuron differentiation|regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|thymus development|thymus development|neuron fate specification|generation of neurons|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|skeletal system morphogenesis|inner ear development|anatomical structure development|myoblast migration|pharyngeal system development|otic vesicle development|otic vesicle development|renal system development|metanephric mesenchyme development|regulation of branch elongation involved in ureteric bud branching|positive regulation of ureteric bud formation|mesonephric tubule formation|ureter smooth muscle cell differentiation|positive regulation of secondary heart field cardioblast proliferation|cochlea morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|negative regulation of branching involved in ureteric bud morphogenesis|positive regulation of mesenchymal cell proliferation involved in ureter development|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.7,2.2,10,0.2,0.384,0.3,2.09,2.09,0.38,0,0,-1.3,1.6
ENSMUSG00000050663,TRHDE,TRH-degrading enzyme,membrane|integral component of membrane|extracellular vesicular exosome|,proteolysis|biological_process|,aminopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.3,2.49,10,-0.1,0.000556,-0.2,2.08,-2.08,0.381,0,0,-1.5,0.7
ENSMUSG00000021079,TIMM9,translocase of inner mitochondrial membrane 9,mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|mitochondrial intermembrane space protein transporter complex|mitochondrial intermembrane space protein transporter complex|,transport|protein transport|protein import into mitochondrial inner membrane|protein import into mitochondrial inner membrane|chaperone-mediated protein transport|,transporter activity|protein homodimerization activity|metal ion binding|chaperone binding|,10,0.2,0.49,10,0.4,1.83,0.4,2.08,2.08,0.381,0,0,-0.6,1.6
ENSMUSG00000006218,FAM131C,"family with sequence similarity 131, member C",cellular_component|,biological_process|,molecular_function|,10,-0.5,2.61,10,-0.1,0.166,-0.3,2.06,-2.06,0.384,0,0,-1.6,0.6
ENSMUSG00000033684,QSOX1,quiescin Q6 sulfhydryl oxidase 1,extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|extracellular vesicular exosome|,protein folding|cell redox homeostasis|oxidation-reduction process|,protein disulfide isomerase activity|oxidoreductase activity|flavin-linked sulfhydryl oxidase activity|flavin-linked sulfhydryl oxidase activity|thiol oxidase activity|,10,-0.1,0.177,10,-0.3,2.24,-0.3,2.06,-2.06,0.384,0,0,-1.7,0.5
ENSMUSG00000048764,TMPRSS11F,"transmembrane protease, serine 11f",cellular_component|extracellular region|integral component of plasma membrane|membrane|integral component of membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,-1.1,3.55,9,-0.3,0.923,-0.8,2.06,-2.06,0.384,0,0,-2,0.7
ENSMUSG00000026247,ECEL1,endothelin converting enzyme-like 1,intracellular|integral component of plasma membrane|membrane|integral component of membrane|,respiratory system process|proteolysis|neuropeptide signaling pathway|intracellular signal transduction|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,-0.3,1.61,10,-0.7,0.984,-0.3,2.06,-2.06,0.384,0,0,-1.7,0.9
ENSMUSG00000044080,S100A1,S100 calcium binding protein A1,nucleus|cytoplasm|sarcoplasmic reticulum|sarcoplasmic reticulum|Z disc|M band|A band|I band|neuron projection|,negative regulation of transcription from RNA polymerase II promoter|regulation of heart contraction|positive regulation of voltage-gated calcium channel activity|,calcium ion binding|protein binding|identical protein binding|protein homodimerization activity|S100 protein binding|metal ion binding|calcium-dependent protein binding|ATPase binding|,10,0.3,2.13,10,1.1,1.14,0.3,2.06,2.06,0.384,0,0,-1.2,1.9
ENSMUSG00000038776,EPHX1,"epoxide hydrolase 1, microsomal",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,cellular aromatic compound metabolic process|response to toxic substance|response to organic cyclic compound|aromatic compound catabolic process|,catalytic activity|epoxide hydrolase activity|hydrolase activity|enzyme binding|cis-stilbene-oxide hydrolase activity|,10,-0.3,2.64,10,0.1,0.077,-0.3,2.04,-2.04,0.386,0,0,-1.5,0.7
ENSMUSG00000038208,PGAP3,post-GPI attachment to proteins 3,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|,GPI anchor metabolic process|GPI anchor biosynthetic process|,"hydrolase activity, acting on ester bonds|",10,-0.5,1.99,10,-0.3,0.224,-0.5,2.04,-2.04,0.386,0,0,-1.8,0.4
ENSMUSG00000024294,MIB1,mindbomb homolog 1 (Drosophila),cytoplasm|centrosome|cytoskeleton|plasma membrane|postsynaptic density|membrane|cytoplasmic vesicle|,blood vessel development|in utero embryonic development|somitogenesis|neural tube formation|heart looping|Notch signaling pathway|heart development|protein ubiquitination|negative regulation of neuron differentiation|positive regulation of endocytosis|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,1.96,10,-0.1,0.451,-0.2,2.02,-2.02,0.389,0,0,-1.5,0.8
ENSMUSG00000062727,HIST1H2BK,"histone cluster 1, H2bk",nucleosome|extracellular space|nucleus|chromosome|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,DNA binding|protein heterodimerization activity|,5,1.2,2.88,5,0.4,0.974,1.1,2.02,2.02,0.389,0,0,-0.6,2
ENSMUSG00000039157,FAM102A,"family with sequence similarity 102, member A",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.561,9,-0.4,1.75,-0.3,2.02,-2.02,0.389,0,0,-1.7,0.5
ENSMUSG00000018666,CBX1,chromobox 1,"chromosome, centromeric region|chromatin|chromatin|female pronucleus|male pronucleus|nucleus|centromeric heterochromatin|spindle|chromocenter|","negative regulation of transcription, DNA-templated|",protein binding|enzyme binding|identical protein binding|protein homodimerization activity|histone methyltransferase binding|,10,0.3,1.72,10,0.2,0.657,0.2,2.01,2.01,0.39,0,0,-0.6,1.6
ENSMUSG00000029500,PGAM5,phosphoglycerate mutase family member 5,mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,programmed cell death|dephosphorylation|positive regulation of GTPase activity|necroptotic process|necroptotic process|,phosphoprotein phosphatase activity|GTPase activator activity|hydrolase activity|phosphatase activity|protein complex binding|,10,-0.2,0.601,10,-0.2,1.55,-0.2,2,-2,0.391,0,0,-1.5,1
ENSMUSG00000020211,SF3A2,"splicing factor 3a, subunit 2",nucleus|,"RNA splicing, via transesterification reactions|mRNA splicing, via spliceosome|",protein binding|metal ion binding|,7,1.1,4.5,7,-1.1,4.69,0.7,1.99,1.99,0.392,0,0,-1.9,1.8
ENSMUSG00000025413,TTC4,tetratricopeptide repeat domain 4,cellular_component|,biological_process|,molecular_function|,9,-1.1,0.831,9,0.4,1.64,0.4,1.98,1.98,0.393,0,0,-1.6,1.6
ENSMUSG00000041000,TRIM62,tripartite motif-containing 62,cellular_component|intracellular|cytoplasm|,negative regulation of viral transcription|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|regulation of viral entry into host cell|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|regulation of viral release from host cell|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,2.54,10,-0.8,1.02,0.3,1.97,1.97,0.395,0,0,-1.5,1.4
ENSMUSG00000069309,HIST1H2AN,"histone cluster 1, H2an",nucleus|extracellular vesicular exosome|,biological_process|,enzyme binding|,6,0.1,0.22,6,0.7,2.6,0.3,1.97,1.97,0.395,0,0,-1,2
ENSMUSG00000015665,AWAT1,acyl-CoA wax alcohol acyltransferase 1,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|biological_process|,"molecular_function|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|long-chain-alcohol O-fatty-acyltransferase activity|",10,0.6,3.5,10,0.1,0.209,0.5,1.97,1.97,0.395,0,0,-0.6,1.9
ENSMUSG00000075419,DOLK,dolichol kinase,endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,phosphorylation|dolichyl monophosphate biosynthetic process|,dolichol kinase activity|kinase activity|transferase activity|,8,-0.2,0.25,8,0.7,3.56,0.6,1.96,1.96,0.396,0,0,-0.5,1.9
ENSMUSG00000003421,NOSIP,nitric oxide synthase interacting protein,nucleus|cytoplasm|,negative regulation of catalytic activity|negative regulation of nitric-oxide synthase activity|,poly(A) RNA binding|,10,0.2,0.469,10,0.2,1.64,0.2,1.96,1.96,0.396,0,0,-0.8,1.5
ENSMUSG00000020850,PRPF8,pre-mRNA processing factor 8,nucleus|spliceosomal complex|U5 snRNP|membrane|ribonucleoprotein complex|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",nucleic acid binding|RNA binding|U6 snRNA binding|U5 snRNA binding|poly(A) RNA binding|,8,0.7,4.05,7,-0.2,0.531,0.6,1.96,1.96,0.396,0,0,-0.6,2
ENSMUSG00000048582,GJA3,"gap junction protein, alpha 3",plasma membrane|gap junction|gap junction|connexon complex|membrane|integral component of membrane|cell junction|membrane raft|,transport|cell communication|response to pH|response to hydrogen peroxide|transmembrane transport|,gap junction channel activity|identical protein binding|,10,0.2,1.54,10,0.2,0.551,0.2,1.95,1.95,0.397,0,0,-0.8,1.6
ENSMUSG00000000581,C1D,C1D nuclear receptor co-repressor,nucleus|nucleolus|cytoplasm|transcriptional repressor complex|,"maturation of 5.8S rRNA|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|apoptotic process|negative regulation of transcription, DNA-templated|",DNA binding|transcription corepressor activity|RNA binding|protein binding|ligand-dependent nuclear receptor binding|,9,-0.4,3.03,7,0.1,0.0486,-0.3,1.94,-1.94,0.398,0,0,-1.8,0.7
ENSMUSG00000021840,MAPK1IP1L,mitogen-activated protein kinase 1 interacting protein 1-like,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0412,10,-0.4,2.64,-0.3,1.94,-1.94,0.398,0,0,-1.5,0.7
ENSMUSG00000034189,HSDL1,hydroxysteroid dehydrogenase like 1,mitochondrion|,biological_process|metabolic process|,molecular_function|oxidoreductase activity|,9,-0.3,1.69,9,-0.3,0.375,-0.3,1.93,-1.93,0.399,0,0,-1.6,0.8
ENSMUSG00000042082,ARSB,arylsulfatase B,mitochondrion|lysosome|rough endoplasmic reticulum|Golgi apparatus|extracellular vesicular exosome|,autophagy|central nervous system development|response to nutrient|metabolic process|response to pH|response to estrogen|response to methylmercury|,catalytic activity|N-acetylgalactosamine-4-sulfatase activity|arylsulfatase activity|sulfuric ester hydrolase activity|hydrolase activity|metal ion binding|,10,-0.4,2.83,10,0,0,-0.3,1.91,-1.91,0.402,0,0,-1.6,0.7
ENSMUSG00000020020,USP44,ubiquitin specific peptidase 44,nucleus|nucleus|,proteolysis|ubiquitin-dependent protein catabolic process|cell cycle|mitotic nuclear division|protein deubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|cell division|anaphase|negative regulation of mitotic anaphase-promoting complex activity|regulation of spindle checkpoint|regulation of mitotic cell cycle spindle assembly checkpoint|,ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|metal ion binding|,10,-0.3,1.48,10,-0.2,0.613,-0.3,1.91,-1.91,0.402,0,0,-1.5,0.9
ENSMUSG00000003199,MPND,MPN domain containing,cellular_component|,proteolysis|biological_process|,molecular_function|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.6,2.72,10,0.1,0.29,0.4,1.91,1.91,0.402,0,0,-0.3,1.7
ENSMUSG00000020952,SCFD1,Sec1 family domain containing 1,cytoplasm|endoplasmic reticulum|Golgi apparatus|Golgi-associated vesicle|cis-Golgi network|plasma membrane|membrane|Golgi transport complex|,"transport|retrograde vesicle-mediated transport, Golgi to ER|post-Golgi vesicle-mediated transport|vesicle docking involved in exocytosis|protein transport|vesicle-mediated transport|regulation of ER to Golgi vesicle-mediated transport|",syntaxin binding|protein N-terminus binding|,8,-0.4,1.66,7,-0.7,0.844,-0.4,1.91,-1.91,0.402,0,0,-2,0.9
ENSMUSG00000040269,MRPS28,mitochondrial ribosomal protein S28,mitochondrion|mitochondrion|ribosome|ribonucleoprotein complex|,biological_process|,poly(A) RNA binding|,10,-0.4,2.04,10,0.6,3.58,0.4,1.91,1.91,0.402,0,0,-1.1,1.6
ENSMUSG00000038121,FAM210A,"family with sequence similarity 210, member A",mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.5,2.08,8,1.1,1.11,1,1.91,1.91,0.402,0,0,-1,2
ENSMUSG00000039182,AW209491,expressed sequence AW209491,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0641,10,-0.8,4.37,-0.7,1.89,-1.89,0.405,0,0,-2,0.4
ENSMUSG00000041578,CRX,cone-rod homeobox,nucleus|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|visual perception|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|response to stimulus|retina development in camera-type eye|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|nuclear hormone receptor binding|leucine zipper domain binding|sequence-specific DNA binding|,10,0.1,0.0123,10,-0.4,2.65,-0.3,1.89,-1.89,0.405,0,0,-1.6,0.8
ENSMUSG00000026764,KIF5C,kinesin family member 5C,cytoplasm|kinesin complex|kinesin complex|ciliary rootlet|neuron projection|,motor neuron axon guidance|,microtubule motor activity|protein binding|apolipoprotein receptor binding|,10,-0.3,1.5,10,-0.3,0.532,-0.3,1.89,-1.89,0.405,0,0,-1.7,0.5
ENSMUSG00000067148,POLR1C,polymerase (RNA) I polypeptide C,nucleus|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase I complex|DNA-directed RNA polymerase I complex|,"transcription, DNA-templated|biological_process|",RNA polymerase I activity|RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|protein dimerization activity|,8,0.5,2.46,7,-0.7,0.693,0.4,1.88,1.88,0.406,0,0,-1.5,1.8
ENSMUSG00000087408,CERS1,ceramide synthase 1,endoplasmic reticulum|,brain development|sphingolipid biosynthetic process|cellular response to drug|cellular response to mycotoxin|ceramide biosynthetic process|negative regulation of telomerase activity|cellular response to UV-A|cellular response to dithiothreitol|,None,10,0,0,10,1.2,5.19,1.1,1.88,1.88,0.406,0,0,-0.2,2
ENSMUSG00000026712,MRC1,"mannose receptor, C type 1",endosome|plasma membrane|cell surface|endosome membrane|membrane|integral component of membrane|,endocytosis|receptor-mediated endocytosis|signal transduction|,receptor activity|transmembrane signaling receptor activity|mannose binding|carbohydrate binding|,10,-0.9,3.56,10,-0.2,0.498,-0.7,1.87,-1.87,0.407,0,0,-1.8,0.4
ENSMUSG00000056598,LRRC48,leucine rich repeat containing 48,cytoplasm|,biological_process|,molecular_function|,10,-1.6,5.29,10,0.3,0.824,-1.6,1.87,-1.87,0.407,0,0,-3,0.4
ENSMUSG00000024991,EIF3A,"eukaryotic translation initiation factor 3, subunit A","nucleus|nucleolus|cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|cytoskeleton|membrane|eukaryotic translation initiation factor 3 complex, eIF3m|",formation of translation initiation complex|formation of translation initiation complex|translation|translational initiation|,translation initiation factor activity|translation initiation factor activity|protein binding|poly(A) RNA binding|,9,-0.4,1.84,8,-0.2,0.267,-0.4,1.87,-1.87,0.407,0,0,-1.6,1.1
ENSMUSG00000020677,DDX52,DEAD (Asp-Glu-Ala-Asp) box polypeptide 52,nucleus|nucleolus|membrane|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,8,-0.9,0.702,8,0.8,4.42,-0.6,1.86,-1.86,0.408,0,0,-1.5,1.8
ENSMUSG00000004044,PTRF,polymerase I and transcript release factor,nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|endoplasmic reticulum|plasma membrane|caveola|caveola|caveola|membrane|intracellular membrane-bounded organelle|protein complex|,"transcription, DNA-templated|DNA-templated transcription, termination|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase I promoter|transcription initiation from RNA polymerase I promoter|termination of RNA polymerase I transcription|termination of RNA polymerase I transcription|",RNA binding|rRNA binding|rRNA primary transcript binding|rRNA primary transcript binding|poly(A) RNA binding|,10,0.1,0.0408,10,0.6,3.06,0.4,1.86,1.86,0.408,0,0,-0.5,1.7
ENSMUSG00000021576,PDCD6,programmed cell death 6,nucleus|cytoplasm|cytoplasm|endosome|endoplasmic reticulum|membrane|cytoplasmic vesicle|extracellular vesicular exosome|,angiogenesis|positive regulation of endothelial cell proliferation|proteolysis|intracellular protein transport|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of endothelial cell migration|negative regulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of TOR signaling|cellular response to heat|vascular endothelial growth factor receptor-2 signaling pathway|positive regulation of angiogenesis|response to calcium ion|negative regulation of protein kinase B signaling|,"calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|protein binding|protein homodimerization activity|metal ion binding|protein dimerization activity|protein dimerization activity|calcium-dependent protein binding|calcium-dependent protein binding|binding, bridging|",10,-0.8,3.22,10,-0.2,0.614,-0.4,1.86,-1.86,0.408,0,0,-1.9,0.7
ENSMUSG00000021539,LECT2,leukocyte cell-derived chemotaxin 2,extracellular region|,chemotaxis|negative regulation of Wnt signaling pathway|,identical protein binding|identical protein binding|,10,-2,5.32,10,0.1,0.0553,-2,1.85,-1.85,0.41,0,0,-4,0.2
ENSMUSG00000020541,TOM1L1,target of myb1-like 1 (chicken),intracellular|cytoplasm|endosome|Golgi apparatus|cytosol|membrane|extracellular vesicular exosome|,transport|intracellular protein transport|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|protein transport|positive regulation of protein autophosphorylation|activation of protein kinase activity|negative regulation of mitosis|positive regulation of protein kinase activity|,protein binding|SH3 domain binding|protein kinase binding|clathrin binding|protein kinase activator activity|,10,1.3,5.08,10,0,0,1.3,1.85,1.85,0.41,0,0,-0.5,2
ENSMUSG00000047619,DDI1,"DDI1, DNA-damage inducible 1, homolog 1 (S. cerevisiae)",cellular_component|,proteolysis|,aspartic-type endopeptidase activity|,8,0.4,1.27,8,0.3,0.833,0.4,1.84,1.84,0.411,0,0,-0.6,1.8
ENSMUSG00000047155,CYP4X1,"cytochrome P450, family 4, subfamily x, polypeptide 1",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,biological_process|oxidation-reduction process|,"molecular_function|monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|metal ion binding|aromatase activity|",10,0.2,0.728,10,0.8,1.71,0.5,1.84,1.84,0.411,0,0,-0.7,1.9
ENSMUSG00000039934,GSAP,gamma-secretase activating protein,Golgi apparatus|trans-Golgi network|,regulation of proteolysis|positive regulation of beta-amyloid formation|positive regulation of beta-amyloid formation|,beta-amyloid binding|,10,0.3,2.08,10,0.1,0.304,0.3,1.84,1.84,0.411,0,0,-0.6,1.8
ENSMUSG00000001105,IFT20,intraflagellar transport 20,photoreceptor outer segment|intracellular|cell|cytoplasm|Golgi apparatus|centrosome|centrosome|centriole|cytoskeleton|cilium|cilium|intraciliary transport particle B|motile cilium|photoreceptor connecting cilium|ciliary basal body|cell projection|dendrite terminus|extracellular vesicular exosome|primary cilium|ciliary base|,kidney development|smoothened signaling pathway|visual learning|neurogenesis|cell projection organization|protein localization to Golgi apparatus|protein localization to Golgi apparatus|photoreceptor cell outer segment organization|opsin transport|intraciliary transport|intraciliary transport|cilium assembly|cilium assembly|centrosome localization|cardiac muscle cell differentiation|regulation of canonical Wnt signaling pathway|neural precursor cell proliferation|protein localization to cilium|protein localization to cilium|regulation of cilium assembly|regulation of autophagic vacuole assembly|,opsin binding|protein binding|,10,0.6,3.55,10,-0.3,0.619,0.5,1.84,1.84,0.411,0,0,-1.2,1.8
ENSMUSG00000028937,ACOT7,acyl-CoA thioesterase 7,nucleus|cytoplasm|cytosol|cytosol|neuron projection|cell body|extracellular vesicular exosome|,fatty acid catabolic process|coenzyme A biosynthetic process|medium-chain fatty-acyl-CoA catabolic process|long-chain fatty-acyl-CoA catabolic process|medium-chain fatty acid biosynthetic process|palmitic acid biosynthetic process|,fatty-acyl-CoA binding|palmitoyl-CoA hydrolase activity|palmitoyl-CoA hydrolase activity|hydrolase activity|long-chain fatty acyl-CoA binding|protein homodimerization activity|acyl-CoA hydrolase activity|,10,-0.2,0.77,10,-0.8,2.31,-0.2,1.83,-1.83,0.412,0,0,-1.9,0.3
ENSMUSG00000048693,OLFR435,olfactory receptor 435,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,1.42,10,-0.4,0.657,-0.3,1.83,-1.83,0.412,0,0,-1.6,0.9
ENSMUSG00000029560,SNX8,sorting nexin 8,endosome|membrane|retromer complex|early endosome membrane|,transport|intracellular protein transport|intracellular protein transport|protein transport|early endosome to Golgi transport|,lipid binding|phosphatidylinositol binding|phosphatidylinositol binding|identical protein binding|,10,-0.5,1.65,10,-0.2,0.772,-0.3,1.82,-1.82,0.414,0,0,-1.6,0.8
ENSMUSG00000020534,SHMT1,serine hydroxymethyltransferase 1 (soluble),nucleus|cytoplasm|mitochondrion|cytosol|extracellular vesicular exosome|,glycine metabolic process|glycine biosynthetic process|L-serine metabolic process|L-serine catabolic process|one-carbon metabolic process|purine nucleobase biosynthetic process|glycine biosynthetic process from serine|folic acid metabolic process|protein tetramerization|protein homotetramerization|,catalytic activity|glycine hydroxymethyltransferase activity|L-allo-threonine aldolase activity|amino acid binding|transferase activity|pyridoxal phosphate binding|identical protein binding|protein homodimerization activity|,10,-0.5,2.83,10,0.1,0.165,-0.4,1.82,-1.82,0.414,0,0,-1.6,0.7
ENSMUSG00000019905,GPRC6A,"G protein-coupled receptor, family C, group 6, member A",intracellular|plasma membrane|cell surface|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|calcium-mediated signaling|response to amino acid|response to amino acid|,signal transducer activity|G-protein coupled receptor activity|,10,0.3,1.17,10,0.8,1.75,0.7,1.81,1.81,0.415,0,0,-0.5,1.9
ENSMUSG00000046152,FUT10,fucosyltransferase 10,Golgi membrane|cellular_component|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|cerebral cortex radially oriented cell migration|fucosylation|neuronal stem cell maintenance|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.3,1.64,10,0.4,0.362,0.4,1.81,1.81,0.415,0,0,-1.8,1.5
ENSMUSG00000027344,FSIP1,fibrous sheath-interacting protein 1,motile cilium|,biological_process|,protein binding|,10,-0.6,3.78,10,0.1,0.103,-0.5,1.79,-1.79,0.418,0,0,-1.8,0.8
ENSMUSG00000026999,NUP35,nucleoporin 35,nucleus|nuclear lamina|plasma membrane|nuclear membrane|intracellular membrane-bounded organelle|intermediate filament cytoskeleton|,biological_process|,protein homodimerization activity|,10,-0.1,0.19,10,-1.3,3.96,0.3,1.78,1.78,0.419,0,0,-2.7,1.1
ENSMUSG00000074212,DNAJB14,"DnaJ (Hsp40) homolog, subfamily B, member 14",membrane|membrane|integral component of membrane|,biological_process|,None,10,-0.5,4.2,10,0.3,1.18,-0.4,1.77,-1.77,0.42,0,0,-1.6,0.9
ENSMUSG00000035385,CCL2,chemokine (C-C motif) ligand 2,extracellular region|extracellular space|extracellular space|cytoplasm|rough endoplasmic reticulum|endocytic vesicle|dendrite|neuronal cell body|perikaryon|axon terminus|C-fiber|synapse|perinuclear region of cytoplasm|,angiogenesis|positive regulation of leukocyte mediated cytotoxicity|positive regulation of endothelial cell proliferation|leukocyte migration involved in inflammatory response|positive regulation of leukocyte migration|positive regulation of cellular extravasation|cellular calcium ion homeostasis|chemotaxis|inflammatory response|immune response|cytoskeleton organization|transforming growth factor beta receptor signaling pathway|glial cell migration|regulation of cell shape|response to heat|response to wounding|regulation of vascular endothelial growth factor production|positive regulation of macrophage chemotaxis|positive regulation of macrophage chemotaxis|negative regulation of angiogenesis|cytokine-mediated signaling pathway|positive regulation of cell-cell adhesion|neutrophil chemotaxis|positive regulation of tumor necrosis factor production|positive regulation of collagen biosynthetic process|helper T cell extravasation|monocyte homeostasis|positive regulation of cell adhesion|vascular endothelial growth factor receptor signaling pathway|eosinophil chemotaxis|macrophage chemotaxis|lymphocyte chemotaxis|positive regulation of synaptic transmission|positive regulation of T cell activation|positive regulation of nitric-oxide synthase biosynthetic process|chemokine-mediated signaling pathway|cellular response to lipopolysaccharide|cellular response to interferon-gamma|cellular response to interleukin-1|cellular response to tumor necrosis factor|positive regulation of monocyte chemotaxis|positive regulation of immune complex clearance by monocytes and macrophages|positive regulation of apoptotic cell clearance|,G-protein coupled receptor binding|cytokine activity|protein binding|chemokine activity|heparin binding|CCR2 chemokine receptor binding|CCR2 chemokine receptor binding|,10,0.7,3.26,10,-1.2,1.9,0.3,1.76,1.76,0.421,0,0,-1.9,1.4
ENSMUSG00000041712,UBR7,ubiquitin protein ligase E3 component n-recognin 7 (putative),cellular_component|,biological_process|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,1.89,10,0,0,0.2,1.75,1.75,0.423,0,0,-0.9,1.5
ENSMUSG00000027282,MTCH2,mitochondrial carrier homolog 2 (C. elegans),nucleus|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|protein localization to mitochondrion|protein localization to mitochondrion|hepatocyte apoptotic process|regulation of mitochondrial membrane permeability involved in apoptotic process|,molecular_function|,10,-0.6,1.46,10,0.7,1.94,-0.7,1.75,-1.75,0.423,0,0,-1.8,1.2
ENSMUSG00000036913,TRIM67,tripartite motif-containing 67,intracellular|cytoplasm|cytoskeleton|,positive regulation of neuron projection development|positive regulation of neuron projection development|negative regulation of Ras protein signal transduction|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,protein binding|zinc ion binding|metal ion binding|,10,-0.3,1.83,10,-0.1,0.415,-0.2,1.74,-1.74,0.424,0,0,-1.6,0.7
ENSMUSG00000040714,KLC3,kinesin light chain 3,intracellular|cell|cytoplasm|cytoskeleton|kinesin complex|microtubule|cilium|motile cilium|ciliary rootlet|ciliary rootlet|neuron projection|,axon cargo transport|intraciliary transport|,microtubule motor activity|protein binding|microtubule binding|kinesin binding|,10,0,0,10,1.2,4.37,0.2,1.74,1.74,0.424,0,0,-0.2,2
ENSMUSG00000018548,TRIM37,tripartite motif-containing 37,intracellular|cytoplasm|peroxisome|cytosol|aggresome|,negative regulation of NF-kappaB transcription factor activity|negative regulation of centriole replication|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein autoubiquitination|aggresome assembly|,"chromatin binding|ubiquitin-protein transferase activity|tumor necrosis factor receptor binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|protein homodimerization activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,1.02,10,0.3,0.845,0.3,1.73,1.73,0.426,0,0,-0.6,1.8
ENSMUSG00000018537,PCGF2,polycomb group ring finger 2,nuclear chromatin|sex chromatin|nucleus|nucleus|nuclear body|PcG protein complex|PcG protein complex|PRC1 complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|anterior/posterior pattern specification|anterior/posterior pattern specification|histone acetylation|embryonic skeletal system morphogenesis|embryonic skeletal system development|cellular response to hydrogen peroxide|negative regulation of apoptotic signaling pathway|",DNA binding|chromatin binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|metal ion binding|,10,0.3,0.906,10,0.8,1.18,0.4,1.72,1.72,0.427,0,0,-0.4,1.8
ENSMUSG00000015846,RXRA,retinoid X receptor alpha,nuclear chromatin|nucleus|nucleus|axon|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|placenta development|maternal placenta development|heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|heart development|heart development|embryo implantation|negative regulation of cell proliferation|negative regulation of gene expression|modulation by virus of host morphology or physiology|regulation of myelination|response to retinoic acid|peroxisome proliferator activated receptor signaling pathway|camera-type eye development|positive regulation of apoptotic process|steroid hormone mediated signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|retinoic acid receptor signaling pathway|retinoic acid receptor signaling pathway|protein homotetramerization|response to glucocorticoid|cardiac muscle cell differentiation|ventricular cardiac muscle tissue morphogenesis|ventricular cardiac muscle cell differentiation|ventricular cardiac muscle cell differentiation|cardiac muscle cell proliferation|cardiac muscle cell proliferation|cardiac muscle cell proliferation|mesenchyme development|secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development|regulation of branching involved in prostate gland morphogenesis|angiogenesis involved in coronary vascular morphogenesis|visceral serous pericardium development|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|9-cis retinoic acid receptor activity|protein binding|transcription factor binding|zinc ion binding|enzyme binding|protein domain specific binding|chromatin DNA binding|protein complex binding|vitamin D receptor binding|retinoic acid receptor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|retinoic acid-responsive element binding|metal ion binding|protein heterodimerization activity|vitamin D response element binding|,9,0.2,1.46,9,0.2,0.354,0.2,1.69,1.69,0.431,0,0,-0.8,1.7
ENSMUSG00000042312,S100A13,S100 calcium binding protein A13,extracellular region|extracellular space|extracellular space|nucleus|cytoplasm|cytosol|perinuclear region of cytoplasm|extracellular vesicular exosome|,transport|positive regulation of cell proliferation|regulation of cell shape|protein transport|positive regulation of I-kappaB kinase/NF-kappaB signaling|cytokine secretion|interleukin-1 alpha secretion|,copper ion binding|calcium ion binding|zinc ion binding|lipid binding|fibroblast growth factor binding|protein homodimerization activity|metal ion binding|RAGE receptor binding|,10,-1.3,4.13,10,0.3,0.941,-1.3,1.68,-1.68,0.432,0,0,-2,0.4
ENSMUSG00000036052,DNAJB5,"DnaJ (Hsp40) homolog, subfamily B, member 5",nucleus|cytosol|cytosol|,negative regulation of transcription from RNA polymerase II promoter|protein folding|,protein binding|unfolded protein binding|chaperone binding|,10,0.1,0.314,10,0.4,1.97,0.3,1.67,1.67,0.434,0,0,-0.6,1.6
ENSMUSG00000032079,APOA5,apolipoprotein A-V,extracellular region|extracellular space|very-low-density lipoprotein particle|high-density lipoprotein particle|chylomicron|,triglyceride metabolic process|triglyceride metabolic process|transport|lipid transport|positive regulation of triglyceride catabolic process|positive regulation of very-low-density lipoprotein particle remodeling|triglyceride catabolic process|triglyceride-rich lipoprotein particle remodeling|lipoprotein metabolic process|cholesterol homeostasis|positive regulation of fatty acid biosynthetic process|positive regulation of lipid catabolic process|positive regulation of lipoprotein lipase activity|acylglycerol homeostasis|acylglycerol homeostasis|triglyceride homeostasis|,phospholipid binding|enzyme activator activity|heparin binding|heparin binding|lipid binding|enzyme binding|phosphatidylcholine binding|lipase binding|low-density lipoprotein particle receptor binding|lipase activator activity|lipoprotein lipase activator activity|lipoprotein particle receptor binding|,10,-0.3,1.59,10,-0.2,0.501,-0.3,1.67,-1.67,0.434,0,0,-1.5,0.9
ENSMUSG00000022420,DNAL4,"dynein, axonemal, light chain 4",cytoplasm|cytoskeleton|microtubule|microtubule associated complex|cilium|dynein complex|cell projection|,microtubule-based process|,motor activity|,10,0.3,1.69,9,0.1,0.263,0.2,1.67,1.67,0.434,0,0,-0.8,1.6
ENSMUSG00000002992,APOC2,apolipoprotein C-II,extracellular region|extracellular space|very-low-density lipoprotein particle|low-density lipoprotein particle|intermediate-density lipoprotein particle|spherical high-density lipoprotein particle|chylomicron|extracellular vesicular exosome|,lipid metabolic process|transport|lipid transport|positive regulation of phospholipase activity|positive regulation of triglyceride catabolic process|negative regulation of very-low-density lipoprotein particle clearance|lipid catabolic process|negative regulation of cholesterol transport|cholesterol efflux|phospholipid efflux|chylomicron remnant clearance|high-density lipoprotein particle clearance|lipoprotein transport|negative regulation of catalytic activity|positive regulation of fatty acid biosynthetic process|negative regulation of lipid metabolic process|negative regulation of receptor-mediated endocytosis|positive regulation of lipoprotein lipase activity|positive regulation of phospholipid catabolic process|triglyceride homeostasis|,enzyme activator activity|lipid binding|phospholipase activator activity|protein homodimerization activity|phospholipase binding|lipase inhibitor activity|lipoprotein lipase activator activity|,10,1.2,1.94,10,0.4,1,0.6,1.67,1.67,0.434,0,0,-0.1,2
ENSMUSG00000019487,TRIP10,thyroid hormone receptor interactor 10,nucleus|cytoplasm|lysosome|Golgi apparatus|cytoskeleton|microtubule|plasma membrane|membrane|cell projection|intracellular membrane-bounded organelle|extracellular vesicular exosome|,endocytosis|actin cytoskeleton organization|hyperosmotic salinity response|,protein binding|lipid binding|identical protein binding|,10,0,0,10,0.6,4.41,0.6,1.66,1.66,0.435,0,0,-0.3,1.8
ENSMUSG00000063952,BRPF3,"bromodomain and PHD finger containing, 3",MOZ/MORF histone acetyltransferase complex|,histone H3 acetylation|,molecular_function|metal ion binding|,10,0.2,0.382,10,-0.6,3.08,-0.5,1.66,-1.66,0.435,0,0,-1.8,0.6
ENSMUSG00000052595,A1CF,APOBEC1 complementation factor,nucleus|nucleus|nuclear heterochromatin|cytoplasm|cytoplasm|endoplasmic reticulum|apolipoprotein B mRNA editing enzyme complex|apolipoprotein B mRNA editing enzyme complex|,mRNA processing|mRNA localization resulting in posttranscriptional regulation of gene expression|cytidine to uridine editing|mRNA modification|mRNA modification|protein stabilization|,nucleotide binding|nucleic acid binding|RNA binding|single-stranded RNA binding|mRNA binding|cytosine deaminase activity|,10,0.6,0.639,10,0.3,1.29,0.3,1.66,1.66,0.435,0,0,-0.7,1.6
ENSMUSG00000040138,NDP,Norrie disease (pseudoglioma) (human),extracellular region|extracellular space|cell surface|extracellular matrix|extracellular matrix|,"placenta development|Wnt signaling pathway|extracellular matrix-cell signaling|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of sequence-specific DNA binding transcription factor activity|canonical Wnt signaling pathway|canonical Wnt signaling pathway|retina vasculature morphogenesis in camera-type eye|",frizzled binding|frizzled binding|cytokine activity|protein homodimerization activity|,10,-0.4,0.952,10,-0.3,0.851,-0.4,1.65,-1.65,0.437,0,0,-1.7,0.7
ENSMUSG00000026480,NCF2,neutrophil cytosolic factor 2,acrosomal vesicle|nucleolus|cytoplasm|cytoplasm|cytosol|membrane|,NADP catabolic process|superoxide metabolic process|response to glucose|response to organic cyclic compound|response to lipopolysaccharide|cellular response to hormone stimulus|superoxide anion generation|positive regulation of neuron apoptotic process|positive regulation of blood pressure|,protein binding|protein C-terminus binding|superoxide-generating NADPH oxidase activity|superoxide-generating NADPH oxidase activity|Rac GTPase binding|,10,-0.5,2.36,10,0.9,1.6,-0.3,1.65,-1.65,0.437,0,0,-1.2,1.7
ENSMUSG00000025873,FAF2,Fas associated factor family member 2,cytoplasm|endoplasmic reticulum|lipid particle|Cdc48p-Npl4p-Ufd1p AAA ATPase complex|intracellular membrane-bounded organelle|,response to unfolded protein|lipid particle organization|negative regulation of catalytic activity|,ubiquitin protein ligase binding|lipase binding|ubiquitin binding|lipase inhibitor activity|,10,0.4,0.546,8,0.7,1.28,0.4,1.64,1.64,0.439,0,0,-0.7,1.9
ENSMUSG00000029716,TFR2,transferrin receptor 2,cytoplasm|plasma membrane|membrane|integral component of membrane|,cellular iron ion homeostasis|receptor-mediated endocytosis|,transferrin receptor activity|,10,-0.5,1.3,10,-0.2,0.962,-0.3,1.64,-1.64,0.439,0,0,-1.7,1
ENSMUSG00000018405,MRM1,mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae),mitochondrion|,RNA processing|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0.5,2.9,0.4,1.64,1.64,0.439,0,0,-0.9,1.6
ENSMUSG00000024034,TMPRSS3,"transmembrane protease, serine 3",endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|neuronal cell body|,proteolysis|cellular sodium ion homeostasis|sensory perception of sound|,catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|sodium channel regulator activity|,10,0.2,0.569,10,0.3,1.37,0.2,1.63,1.63,0.44,0,0,-0.9,1.5
ENSMUSG00000068854,HIST2H2BE,"histone cluster 2, H2be",nucleosome|extracellular space|nucleus|chromosome|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,DNA binding|protein binding|protein heterodimerization activity|,10,0,0,10,1,4.53,0.9,1.63,1.63,0.44,0,0,-0.5,2
ENSMUSG00000022807,OSBPL11,oxysterol binding protein-like 11,cellular_component|endosome|Golgi apparatus|membrane|,transport|lipid transport|positive regulation of sequestering of triglyceride|fat cell differentiation|,molecular_function|lipid binding|,10,-0.3,1.86,10,0.3,1.24,-0.3,1.63,-1.63,0.44,0,0,-1.4,1.3
ENSMUSG00000037072,15-Sep,selenoprotein,endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|extracellular vesicular exosome|,sperm chromatin condensation|'de novo' posttranslational protein folding|oxidation-reduction process|,protein binding|thioredoxin peroxidase activity|selenium binding|selenium binding|,10,0.4,1.82,10,0.2,0.334,0.2,1.63,1.63,0.44,0,0,-0.5,1.7
ENSMUSG00000033916,CHMP2A,charged multivesicular body protein 2A,cytoplasm|endosome|cytosol|membrane|membrane|extracellular vesicular exosome|,transport|protein transport|establishment of protein localization|regulation of viral process|positive regulation of viral release from host cell|,protein binding|protein domain specific binding|,8,-0.2,0.398,9,-1.2,3.57,-0.2,1.62,-1.62,0.442,0,0,-2,0.5
ENSMUSG00000025192,ENTPD7,ectonucleoside triphosphate diphosphohydrolase 7,nucleus|membrane|integral component of membrane|cytoplasmic vesicle|,ribonucleoside diphosphate catabolic process|ribonucleoside triphosphate catabolic process|,"thiamine-pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|nucleoside-diphosphatase activity|nucleoside-triphosphatase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|",10,-0.2,0.707,10,-0.3,1.22,-0.2,1.61,-1.61,0.443,0,0,-1.9,0.5
ENSMUSG00000058952,CFI,complement component factor i,extracellular region|extracellular space|nucleus|membrane|extracellular vesicular exosome|,"immune system process|proteolysis|complement activation, classical pathway|innate immune response|",catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|metal ion binding|,10,0.1,0.00437,10,0.6,2.29,0.5,1.61,1.61,0.443,0,0,-0.8,1.7
ENSMUSG00000058427,CXCL2,chemokine (C-X-C motif) ligand 2,extracellular region|extracellular space|extracellular space|,response to molecule of bacterial origin|chemotaxis|inflammatory response|immune response|positive regulation of cytosolic calcium ion concentration|neutrophil chemotaxis|leukocyte chemotaxis|neuron death|,cytokine activity|chemokine activity|,9,-0.3,0.454,9,-0.4,1.34,-0.3,1.6,-1.6,0.445,0,0,-1.4,1.6
ENSMUSG00000039202,ABHD2,abhydrolase domain containing 2,membrane|integral component of membrane|,response to wounding|negative regulation of cell migration|,"phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.2,0.992,10,-0.4,1.17,-0.3,1.6,-1.6,0.445,0,0,-1.6,0.8
ENSMUSG00000035293,G2E3,G2/M-phase specific E3 ubiquitin ligase,nucleus|cytoplasm|,protein polyubiquitination|blastocyst development|apoptotic process|multicellular organismal development|negative regulation of intrinsic apoptotic signaling pathway|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.148,10,0.3,1.71,0.2,1.59,1.59,0.446,0,0,-0.8,1.6
ENSMUSG00000030888,RRP8,"ribosomal RNA processing 8, methyltransferase, homolog (yeast)",nucleus|chromatin silencing complex|nucleolus|cytoplasm|plasma membrane|rDNA heterochromatin|,"chromatin silencing at rDNA|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|chromatin modification|methylation|cellular response to glucose starvation|regulation of transcription by glucose|positive regulation of cell cycle arrest|intrinsic apoptotic signaling pathway by p53 class mediator|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|methylated histone binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,1.2,1.54,10,0.3,1.03,0.9,1.59,1.59,0.446,0,0,-0.4,2
ENSMUSG00000041638,GCN1L1,GCN1 general control of amino-acid synthesis 1-like 1 (yeast),cytoplasm|membrane|,biological_process|,protein binding|poly(A) RNA binding|,8,0.4,2.31,7,-1.3,3.74,-1.2,1.59,-1.59,0.446,0,0,-2,0.9
ENSMUSG00000006418,RNF114,ring finger protein 114,intracellular|nucleus|cytoplasm|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,1.07,10,-0.5,3.81,-0.4,1.58,-1.58,0.448,0,0,-1.6,1.2
ENSMUSG00000024889,RCE1,"RCE1 homolog, prenyl protein peptidase (S. cerevisiae)",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,proteolysis|CAAX-box protein processing|,cysteine-type endopeptidase activity|hydrolase activity|,9,0.6,0.583,8,0.8,1.32,0.6,1.57,1.57,0.449,0,0,-0.6,1.9
ENSMUSG00000054200,FFAR4,free fatty acid receptor 4,plasma membrane|membrane|integral component of membrane|endocytic vesicle|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|regulation of glucose transport|negative regulation of apoptotic process|hormone secretion|negative regulation of cytokine secretion|negative regulation of inflammatory response|detection of chemical stimulus involved in sensory perception of taste|positive regulation of ERK1 and ERK2 cascade|,signal transducer activity|G-protein coupled receptor activity|fatty acid binding|protein binding|lipid binding|taste receptor activity|,10,-0.2,0.259,10,1,3.95,0.4,1.56,1.56,0.451,0,0,-1.1,2
ENSMUSG00000036964,TRIM17,tripartite motif-containing 17,cellular_component|intracellular|,protein autoubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.653,10,0.8,1.11,0.2,1.56,1.56,0.451,0,0,-0.5,1.9
ENSMUSG00000031029,EIF3F,"eukaryotic translation initiation factor 3, subunit F","cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|membrane|eukaryotic translation initiation factor 3 complex, eIF3m|",translation|translational initiation|translational initiation|proteolysis|protein deubiquitination|protein deubiquitination|,translation initiation factor activity|translation initiation factor activity|ubiquitin-specific protease activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|translation initiation factor binding|,8,-0.3,0.157,7,0.5,2.2,-0.6,1.56,-1.56,0.451,0,0,-1.9,1.1
ENSMUSG00000034518,HMGXB4,HMG box domain containing 4,NURF complex|,biological_process|,molecular_function|,10,-0.1,0.211,10,0.5,3.58,0.4,1.56,1.56,0.451,0,0,-0.5,1.9
ENSMUSG00000030788,RNF141,ring finger protein 141,cellular_component|,"regulation of transcription, DNA-templated|protein autoubiquitination|",DNA binding|ubiquitin-protein transferase activity|zinc ion binding|metal ion binding|,10,-0.2,0.732,10,-0.2,0.951,-0.2,1.55,-1.55,0.452,0,0,-1.1,1.7
ENSMUSG00000095162,WDR49,WD repeat domain 49,cellular_component|,biological_process|,molecular_function|,10,0.2,0.723,10,0.2,0.946,0.2,1.54,1.54,0.454,0,0,-1,1.6
ENSMUSG00000032540,ABHD5,abhydrolase domain containing 5,nucleus|cytoplasm|lipid particle|lipid particle|cytosol|intracellular membrane-bounded organelle|,lipid metabolic process|fatty acid metabolic process|phosphatidic acid biosynthetic process|phospholipid biosynthetic process|negative regulation of sequestering of triglyceride|negative regulation of sequestering of triglyceride|positive regulation of triglyceride catabolic process|positive regulation of triglyceride catabolic process|cell differentiation|positive regulation of lipoprotein lipase activity|,"1-acylglycerol-3-phosphate O-acyltransferase activity|protein binding|transferase activity|transferase activity, transferring acyl groups|hydrolase activity|lysophosphatidic acid acyltransferase activity|",10,-0.2,0.831,10,-0.3,0.957,-0.2,1.54,-1.54,0.454,0,0,-1.6,0.9
ENSMUSG00000037416,DMXL1,Dmx-like 1,cellular_component|,biological_process|,molecular_function|,10,0.2,0.966,10,0.2,0.696,0.2,1.53,1.53,0.455,0,0,-0.9,1.6
ENSMUSG00000023000,DHH,desert hedgehog,extracellular region|plasma membrane|membrane|,proteolysis|cell communication|cell-cell signaling|multicellular organismal development|spermatid development|intein-mediated protein splicing|male sex determination|Leydig cell differentiation|Leydig cell differentiation|regulation of steroid biosynthetic process|,patched binding|calcium ion binding|protein binding|peptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.5,1.09,10,0.2,0.954,0.3,1.53,1.53,0.455,0,0,-1.4,1.7
ENSMUSG00000040605,BACE2,beta-site APP-cleaving enzyme 2,endosome|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,proteolysis|membrane protein ectodomain proteolysis|negative regulation of amyloid precursor protein biosynthetic process|,aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|,10,0.5,2.8,10,-0.6,2.3,0.4,1.53,1.53,0.455,0,0,-1.3,1.7
ENSMUSG00000031766,SLC12A3,"solute carrier family 12, member 3",cytosol|plasma membrane|plasma membrane|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|vesicle|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|sodium ion transport|chloride transport|sodium ion transmembrane transport|transmembrane transport|chloride transmembrane transport|,transporter activity|sodium ion transmembrane transporter activity|symporter activity|cation:chloride symporter activity|sodium:chloride symporter activity|,10,0.1,0.168,10,-0.5,1.93,-0.5,1.52,-1.52,0.457,0,0,-1.6,1.4
ENSMUSG00000061983,RPS12,ribosomal protein S12,membrane|cytosolic small ribosomal subunit|,None,poly(A) RNA binding|,2,-0.3,0.389,3,-0.4,1.26,-0.3,1.51,-1.51,0.459,0,0,-2,1.4
ENSMUSG00000010796,ASZ1,"ankyrin repeat, SAM and basic leucine zipper domain containing 1",cytoplasm|pi-body|,meiotic nuclear division|male meiosis|signal transduction|multicellular organismal development|germ cell development|spermatogenesis|cell differentiation|gene silencing by RNA|piRNA metabolic process|DNA methylation involved in gamete generation|,signal transducer activity|protein binding|,10,-0.2,0.638,10,-0.3,1.11,-0.3,1.5,-1.5,0.46,0,0,-1.8,1.1
ENSMUSG00000025373,RNF41,ring finger protein 41,cellular_component|,protein polyubiquitination|protein polyubiquitination|apoptotic process|negative regulation of cell proliferation|regulation of gene expression|protein ubiquitination|negative regulation of cell migration|regulation of MAPK cascade|regulation of lymphocyte differentiation|regulation of myeloid cell differentiation|positive regulation of sequence-specific DNA binding transcription factor activity|protein autoubiquitination|regulation of protein kinase B signaling|extrinsic apoptotic signaling pathway|regulation of establishment of cell polarity|regulation of reactive oxygen species metabolic process|,"ubiquitin-protein transferase activity|erythropoietin receptor binding|interleukin-3 receptor binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|acid-amino acid ligase activity|ribosomal S6-glutamic acid ligase activity|protein tag|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.4,2.66,10,0,0,-0.3,1.5,-1.5,0.46,0,0,-1.7,0.5
ENSMUSG00000096025,RALYL,RALY RNA binding protein-like,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.2,0.955,10,-0.3,0.667,-0.2,1.49,-1.49,0.462,0,0,-1.5,1.2
ENSMUSG00000020741,CLUH,clustered mitochondria (cluA/CLU1) homolog,cellular_component|cytoplasm|,biological_process|intracellular distribution of mitochondria|,molecular_function|,10,-0.5,2.37,9,0.1,0.375,-0.4,1.49,-1.49,0.462,0,0,-1.7,0.8
ENSMUSG00000042557,SIN3A,"transcriptional regulator, SIN3A (yeast)",kinetochore|chromatin|nucleus|nucleus|transcription factor complex|cytoplasm|Sin3 complex|transcriptional repressor complex|transcriptional repressor complex|protein complex|intercellular bridge|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|activation of innate immune response|positive regulation of defense response to virus by host|hematopoietic progenitor cell differentiation|DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein deacetylation|aging|response to organonitrogen compound|positive regulation of G2/M transition of mitotic cell cycle|positive regulation of chromatin silencing|cellular protein localization|negative regulation of circadian rhythm|negative regulation of apoptotic process|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|response to methylglyoxal|cellular response to glucose stimulus|negative regulation of protein localization to nucleus|negative regulation of histone H3-K27 acetylation|negative regulation of transcription regulatory region DNA binding|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II activating transcription factor binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II transcription corepressor activity|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|transcription factor binding|protein complex binding|protein deacetylase activity|,10,-0.2,0.329,10,-0.3,1.46,-0.2,1.49,-1.49,0.462,0,0,-1.1,1.8
ENSMUSG00000004285,ATP6V1F,"ATPase, H+ transporting, lysosomal V1 subunit F","membrane|vacuolar proton-transporting V-type ATPase complex|proton-transporting V-type ATPase, V1 domain|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|ion transmembrane transport|,"ATPase activity, coupled to transmembrane movement of ions|proton-transporting ATPase activity, rotational mechanism|",10,-0.6,3.65,10,1,0.724,-0.6,1.48,-1.48,0.463,0,0,-1.7,1.5
ENSMUSG00000025939,UBE2W,ubiquitin-conjugating enzyme E2W (putative),nucleus|,DNA repair|protein monoubiquitination|protein monoubiquitination|protein monoubiquitination|misfolded or incompletely synthesized protein catabolic process|cellular response to DNA damage stimulus|proteasome-mediated ubiquitin-dependent protein catabolic process|protein K11-linked ubiquitination|cellular response to misfolded protein|,nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|ubiquitin protein ligase binding|ubiquitin protein ligase binding|,10,0.2,0.444,10,0.3,1.21,0.3,1.47,1.47,0.465,0,0,-1,1.6
ENSMUSG00000030510,CERS3,ceramide synthase 3,nucleus|membrane|integral component of membrane|,lipid metabolic process|sphingolipid biosynthetic process|keratinocyte differentiation|ceramide biosynthetic process|,DNA binding|transferase activity|sphingosine N-acyltransferase activity|,9,-0.1,0.259,10,1,2.15,0.3,1.46,1.46,0.466,0,0,-1,2
ENSMUSG00000039382,WDR45,WD repeat domain 45,None,autophagy|,None,10,-0.2,0.782,10,-0.2,0.785,-0.2,1.45,-1.45,0.468,0,0,-1.7,0.8
ENSMUSG00000038274,FAU,Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived),extracellular space|small ribosomal subunit|cytosolic small ribosomal subunit|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,structural constituent of ribosome|protein binding|poly(A) RNA binding|,4,-0.7,0.855,3,-0.5,0.884,-0.6,1.45,-1.45,0.468,0,0,-2,1.4
ENSMUSG00000025245,LZTFL1,leucine zipper transcription factor-like 1,cytoplasm|BBSome|BBSome|,establishment of protein localization to organelle|,protein binding|identical protein binding|identical protein binding|,10,-0.1,0.471,10,-0.2,1.14,-0.2,1.45,-1.45,0.468,0,0,-1.5,1
ENSMUSG00000034810,SCN7A,"sodium channel, voltage-gated, type VII, alpha",plasma membrane|membrane|integral component of membrane|glial cell projection|,transport|ion transport|sodium ion transport|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion homeostasis|sodium ion homeostasis|membrane depolarization during action potential|,voltage-gated ion channel activity|voltage-gated sodium channel activity|sodium channel activity|protein binding|,10,-0.4,1.68,10,-0.1,0.225,-0.2,1.45,-1.45,0.468,0,0,-1.7,1
ENSMUSG00000047747,RNF150,ring finger protein 150,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.2,1.12,10,0.2,0.671,-0.2,1.45,-1.45,0.468,0,0,-1.3,1.3
ENSMUSG00000024993,FAM45A,"family with sequence similarity 45, member A",cellular_component|,biological_process|,molecular_function|,10,0.4,1.63,10,-0.4,0.261,0.3,1.43,1.43,0.471,0,0,-0.9,1.8
ENSMUSG00000074064,MLYCD,malonyl-CoA decarboxylase,cytoplasm|mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial matrix|peroxisome|peroxisomal matrix|cytosol|,response to ischemia|acetyl-CoA biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|regulation of glucose metabolic process|fatty acid oxidation|regulation of fatty acid beta-oxidation|regulation of fatty acid oxidation|positive regulation of fatty acid oxidation|positive regulation of fatty acid oxidation|malonyl-CoA catabolic process|malonyl-CoA catabolic process|,receptor binding|protein binding|lyase activity|carboxy-lyase activity|malonyl-CoA decarboxylase activity|malonyl-CoA decarboxylase activity|,10,0.1,0.0846,10,0.3,1.83,0.2,1.43,1.43,0.471,0,0,-1,1.6
ENSMUSG00000029134,PLB1,phospholipase B1,plasma membrane|membrane|integral component of membrane|brush border membrane|,lipid metabolic process|phospholipid metabolic process|lipid catabolic process|retinol metabolic process|positive regulation of acrosome reaction|,"lysophospholipase activity|phospholipase A2 activity|lipase activity|hydrolase activity|hydrolase activity, acting on ester bonds|retinyl-palmitate esterase activity|",10,0.7,0.912,10,0.3,0.956,0.3,1.42,1.42,0.473,0,0,-0.5,1.8
ENSMUSG00000036298,SLC2A13,"solute carrier family 2 (facilitated glucose transporter), member 13",membrane|integral component of membrane|,transport|carbohydrate transport|transmembrane transport|,transporter activity|transmembrane transporter activity|substrate-specific transmembrane transporter activity|,10,0.4,1.64,10,0.2,0.382,0.3,1.42,1.42,0.473,0,0,-0.4,1.9
ENSMUSG00000029595,LHX5,LIM homeobox protein 5,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell-cell signaling|spinal cord association neuron differentiation|cerebellum development|cerebellar Purkinje cell differentiation|hippocampus development|cell proliferation in forebrain|forebrain neuron differentiation|cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation|regulation of cell proliferation|positive regulation of transcription, DNA-templated|",DNA binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.6,2.75,10,0.1,0.04,-0.5,1.41,-1.41,0.474,0,0,-1.8,0.5
ENSMUSG00000025132,ARHGDIA,Rho GDP dissociation inhibitor (GDI) alpha,immunological synapse|intracellular|cytoplasm|extracellular vesicular exosome|,Rho protein signal transduction|negative regulation of cell migration|regulation of protein localization|regulation of catalytic activity|semaphorin-plexin signaling pathway|,Rho GDP-dissociation inhibitor activity|GTPase activator activity|protein binding|,10,1.2,2.58,10,-0.4,3.26,-0.3,1.41,-1.41,0.474,0,0,-0.9,2
ENSMUSG00000028773,FABP3,"fatty acid binding protein 3, muscle and heart",extracellular space|cytoplasm|cytosol|cytosol|sarcoplasm|extracellular vesicular exosome|,transport|long-chain fatty acid transport|cholesterol homeostasis|long-chain fatty acid import|regulation of fatty acid oxidation|phospholipid homeostasis|positive regulation of phospholipid biosynthetic process|regulation of phosphatidylcholine biosynthetic process|,transporter activity|long-chain fatty acid transporter activity|fatty acid binding|cytoskeletal protein binding|lipid binding|long-chain fatty acid binding|icosatetraenoic acid binding|oleic acid binding|,10,0.4,2.9,10,-0.1,0.127,0.3,1.41,1.41,0.474,0,0,-1.1,1.7
ENSMUSG00000001750,TCIRG1,"T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3",mitochondrion|lysosomal membrane|plasma membrane|apical plasma membrane|,None,None,10,-0.4,2.95,10,0,0,-0.3,1.41,-1.41,0.474,0,0,-1.6,1
ENSMUSG00000050627,GPD1L,glycerol-3-phosphate dehydrogenase 1-like,cytoplasm|plasma membrane|glycerol-3-phosphate dehydrogenase complex|membrane|extracellular vesicular exosome|,regulation of heart rate|carbohydrate metabolic process|glycerol-3-phosphate metabolic process|NADH metabolic process|positive regulation of sodium ion transport|NAD metabolic process|negative regulation of peptidyl-serine phosphorylation|glycerol-3-phosphate catabolic process|oxidation-reduction process|regulation of ventricular cardiac muscle cell membrane depolarization|ventricular cardiac muscle cell action potential|negative regulation of protein kinase C signaling|positive regulation of protein localization to cell surface|regulation of sodium ion transmembrane transporter activity|,"glycerol-3-phosphate dehydrogenase [NAD+] activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|sodium channel regulator activity|protein homodimerization activity|ion channel binding|coenzyme binding|NAD binding|",10,0,0,10,-0.3,2.56,-0.2,1.41,-1.41,0.474,0,0,-1.6,0.8
ENSMUSG00000070972,DNAJC25,"DnaJ (Hsp40) homolog, subfamily C, member 25",cellular_component|membrane|integral component of membrane|,biological_process|,None,10,-1.3,3.45,10,-0.2,0.284,-0.2,1.4,-1.4,0.476,0,0,-2,0.8
ENSMUSG00000049792,BAG5,BCL2-associated athanogene 5,nucleus|membrane|inclusion body|inclusion body|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,negative regulation of protein ubiquitination|negative regulation of protein ubiquitination|negative regulation of ubiquitin-protein transferase activity|negative regulation of ubiquitin-protein transferase activity|negative regulation of protein refolding|negative regulation of protein refolding|neuron death|neuron death|regulation of inclusion body assembly|regulation of inclusion body assembly|,ubiquitin protein ligase binding|chaperone binding|chaperone binding|,10,-0.1,0.0796,10,-0.9,2.62,-0.7,1.4,-1.4,0.476,0,0,-2,0.5
ENSMUSG00000024313,MEP1B,meprin 1 beta,plasma membrane|membrane|integral component of membrane|,proteolysis|inflammatory response|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.4,0.723,10,-0.2,1.01,-0.2,1.39,-1.39,0.477,0,0,-1.7,0.7
ENSMUSG00000025730,RAB40C,"Rab40C, member RAS oncogene family",plasma membrane|membrane|perinuclear region of cytoplasm|,small GTPase mediated signal transduction|protein transport|intracellular signal transduction|,nucleotide binding|GTP binding|GDP binding|,9,0.2,0.91,9,0.2,0.59,0.2,1.38,1.38,0.479,0,0,-0.8,1.7
ENSMUSG00000020087,TYSND1,trypsin domain containing 1,peroxisome|membrane|,proteolysis|protein processing|regulation of fatty acid beta-oxidation|protein homooligomerization|,protease binding|catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|identical protein binding|,9,0.2,0.68,9,-0.5,1.26,0.6,1.37,1.37,0.481,0,0,-1.1,1.8
ENSMUSG00000032578,CISH,cytokine inducible SH2-containing protein,plasma membrane|,protein kinase C-activating G-protein coupled receptor signaling pathway|negative regulation of signal transduction|intracellular signal transduction|regulation of growth|,protein binding|,10,0.4,1.82,10,-0.4,0.319,0.3,1.37,1.37,0.481,0,0,-1,1.7
ENSMUSG00000006529,ITIH1,"inter-alpha trypsin inhibitor, heavy chain 1",extracellular region|extracellular vesicular exosome|blood microparticle|,negative regulation of peptidase activity|hyaluronan metabolic process|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.1,0.251,10,-0.7,3.02,-0.5,1.37,-1.37,0.481,0,0,-1.9,0.6
ENSMUSG00000005981,TRAP1,TNF receptor-associated protein 1,nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial intermembrane space|mitochondrial matrix|membrane|membrane|extracellular vesicular exosome|,protein folding|response to stress|negative regulation of cellular respiration|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,nucleotide binding|ATP binding|poly(A) RNA binding|unfolded protein binding|,10,-0.2,2.32,10,0,0,-0.2,1.36,-1.36,0.482,0,0,-1.7,0.8
ENSMUSG00000021259,CYP46A1,"cytochrome P450, family 46, subfamily a, polypeptide 1",endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|cholesterol catabolic process|xenobiotic metabolic process|steroid metabolic process|cholesterol metabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|heme binding|cholesterol 24-hydroxylase activity|metal ion binding|",10,-1,0.722,10,-0.9,0.766,-0.9,1.35,-1.35,0.484,0,0,-2,0.3
ENSMUSG00000006313,UPK1A,uroplakin 1A,membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,endocytosis|signal transduction|epithelial cell differentiation|,protein binding|monosaccharide binding|,10,-0.2,0.144,10,-0.3,1.33,-0.3,1.35,-1.35,0.484,0,0,-1.7,0.8
ENSMUSG00000078622,CCDC47,coiled-coil domain containing 47,endoplasmic reticulum|membrane|integral component of membrane|,osteoblast differentiation|ER overload response|embryo development|post-embryonic development|calcium ion homeostasis|,calcium ion binding|poly(A) RNA binding|,10,0.3,1.09,10,0.2,0.376,0.3,1.32,1.32,0.489,0,0,-0.7,1.8
ENSMUSG00000026426,ARL8A,ADP-ribosylation factor-like 8A,intracellular|cytoplasm|lysosome|lysosomal membrane|endosome|membrane|membrane|midbody|spindle midzone|extracellular vesicular exosome|,cell cycle|chromosome segregation|mitotic nuclear division|small GTPase mediated signal transduction|biological_process|cell division|,nucleotide binding|GTP binding|,10,0.2,0.89,10,1,1.18,0.6,1.3,1.3,0.492,0,0,-0.9,1.9
ENSMUSG00000032091,TMPRSS4,"transmembrane protease, serine 4",membrane|integral component of membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.4,0.952,10,0.2,0.713,0.3,1.3,1.3,0.492,0,0,-0.5,1.9
ENSMUSG00000059714,FLOT1,flotillin 1,lysosomal membrane|endosome|microtubule organizing center|plasma membrane|caveola|caveola|COP9 signalosome|membrane|membrane|flotillin complex|flotillin complex|centriolar satellite|sarcolemma|membrane raft|membrane raft|extracellular vesicular exosome|,endocytosis|axonogenesis|axon guidance|extracellular matrix disassembly|regulation of Rho protein signal transduction|protein localization to plasma membrane|establishment of protein localization to plasma membrane|,protease binding|protein binding|ionotropic glutamate receptor binding|,10,0.4,0.779,10,0.3,0.624,0.4,1.29,1.29,0.494,0,0,-0.6,1.9
ENSMUSG00000037622,WDTC1,WD and tetratricopeptide repeats 1,nucleus|cytosol|,negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|glucose metabolic process|regulation of cell size|cellular response to insulin stimulus|multicellular organism growth|negative regulation of catalytic activity|negative regulation of fatty acid biosynthetic process|negative regulation of fatty acid biosynthetic process|cellular chemical homeostasis|,enzyme inhibitor activity|histone binding|histone deacetylase binding|,10,0.3,0.744,10,0.4,0.731,0.3,1.29,1.29,0.494,0,0,-0.7,1.7
ENSMUSG00000069266,HIST1H4B,"histone cluster 1, H4b",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,7,0.4,0.694,7,-0.6,3.39,-0.6,1.28,-1.28,0.495,0,0,-2,0.9
ENSMUSG00000070371,PRSS36,"protease, serine 36",cytoplasm|,proteolysis|proteolysis|,serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.6,0.985,10,0.2,0.462,0.2,1.28,1.28,0.495,0,0,-1.4,1.5
ENSMUSG00000074170,PLEKHF1,"pleckstrin homology domain containing, family F (with FYVE domain) member 1",nucleus|cytoplasm|mitochondrion|lysosome|lysosome|endosome|,apoptotic process|endosome organization|positive regulation of autophagy|vesicle organization|regulation of mitochondrial membrane permeability|protein localization to plasma membrane|positive regulation of intrinsic apoptotic signaling pathway|,phosphatidylinositol-5-phosphate binding|phosphatidylinositol-3-phosphate binding|metal ion binding|phosphatidylinositol-4-phosphate binding|,10,0,0,10,0.3,1.51,0.2,1.28,1.28,0.495,0,0,-1,1.9
ENSMUSG00000020134,PELI1,pellino 1,nucleus|,protein polyubiquitination|positive regulation of cytokine production|Toll signaling pathway|positive regulation of B cell proliferation|positive regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|response to lipopolysaccharide|positive regulation of toll-like receptor 3 signaling pathway|positive regulation of toll-like receptor 4 signaling pathway|negative regulation of T cell proliferation|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to dsRNA|negative regulation of T cell activation|positive regulation of B cell activation|protein K48-linked ubiquitination|,"ubiquitin-protein transferase activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1.1,4.09,10,0,0,0.8,1.28,1.28,0.495,0,0,-0.3,2
ENSMUSG00000028081,RPS3A1,ribosomal protein S3A1,intracellular|nucleus|cytoplasm|cytosol|ribosome|cytosolic small ribosomal subunit|ribonucleoprotein complex|,cytoplasmic translation|translation|cell differentiation|,structural constituent of ribosome|protein binding|translation initiation factor binding|,2,-0.5,1.19,2,0.6,2.16,0.5,1.27,1.27,0.497,0,0,-1.6,2
ENSMUSG00000022156,GZME,granzyme E,membrane|,cytolysis|,catalytic activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.4,3.02,10,0,0,0.3,1.27,1.27,0.497,0,0,-0.8,1.6
ENSMUSG00000052414,ATF7,activating transcription factor 7,nuclear periphery|,"regulation of transcription, DNA-templated|",transcription factor binding|enzyme binding|mitogen-activated protein kinase binding|,10,-0.4,1.9,10,-0.1,0.2,-0.2,1.27,-1.27,0.497,0,0,-1.7,0.8
ENSMUSG00000039419,CNTNAP2,contactin associated protein-like 2,early endosome|Golgi apparatus|voltage-gated potassium channel complex|voltage-gated potassium channel complex|cell surface|membrane|integral component of membrane|axolemma|juxtaparanode region of axon|,cell adhesion|learning|neuron recognition|adult behavior|neuron projection development|cellular protein localization|social behavior|clustering of voltage-gated potassium channels|protein localization to juxtaparanode region of axon|vocalization behavior|,protease binding|protein binding|enzyme binding|,10,-0.5,2.24,10,0.2,0.342,-0.4,1.26,-1.26,0.499,0,0,-1.4,1.6
ENSMUSG00000092572,SERPINB10,"serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10",cellular_component|extracellular space|nucleus|cytoplasm|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|negative regulation of proteolysis|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.5,2.07,10,0.7,2.85,0.3,1.26,1.26,0.499,0,0,-1.1,1.7
ENSMUSG00000040525,CBLC,Casitas B-lineage lymphoma c,ubiquitin ligase complex|nucleus|extracellular vesicular exosome|,ubiquitin-dependent protein catabolic process|cell surface receptor signaling pathway|negative regulation of epidermal growth factor-activated receptor activity|regulation of signaling|negative regulation of epidermal growth factor receptor signaling pathway|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of MAP kinase activity|,"phosphotyrosine binding|ubiquitin-protein transferase activity|signal transducer activity|epidermal growth factor receptor binding|calcium ion binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|SH3 domain binding|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.931,10,0.4,0.519,0.2,1.26,1.26,0.499,0,0,-0.7,1.7
ENSMUSG00000024759,ATL3,atlastin GTPase 3,endoplasmic reticulum|membrane|membrane|integral component of membrane|,endoplasmic reticulum organization|Golgi organization|protein homooligomerization|,nucleotide binding|GTPase activity|GTP binding|hydrolase activity|identical protein binding|,10,0.4,0.427,10,0.4,0.896,0.4,1.22,1.22,0.506,0,0,-0.4,1.9
ENSMUSG00000029787,AVL9,AVL9 homolog (S. cerevisiase),endosome|membrane|integral component of membrane|recycling endosome|,cell migration|,molecular_function|,10,0.2,0.669,10,0.2,0.657,0.2,1.22,1.22,0.506,0,0,-1,1.6
ENSMUSG00000026943,LCN12,lipocalin 12,cellular_component|extracellular region|,transport|biological_process|,retinoic acid binding|transporter activity|,10,0.2,0.841,10,0.2,0.478,0.2,1.22,1.22,0.506,0,0,-1.1,1.5
ENSMUSG00000005220,CORIN,corin,extracellular region|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|,regulation of systemic arterial blood pressure by atrial natriuretic peptide|regulation of systemic arterial blood pressure by atrial natriuretic peptide|proteolysis|proteolysis|female pregnancy|female pregnancy|regulation of blood pressure|regulation of blood pressure|protein processing|peptide hormone processing|peptide hormone processing|neuron differentiation|regulation of renal sodium excretion|regulation of renal sodium excretion|,catalytic activity|serine-type endopeptidase activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|serine-type exopeptidase activity|,10,-1.1,0.842,10,-0.2,0.896,-0.2,1.21,-1.21,0.508,0,0,-2,0.4
ENSMUSG00000001424,SND1,staphylococcal nuclease and tudor domain containing 1,nucleus|cytoplasm|cytoplasm|mitochondrion|membrane|RISC complex|extracellular vesicular exosome|dense body|,"osteoblast differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|gene silencing by RNA|","nucleic acid binding|nuclease activity|protein binding|hydrolase activity, acting on ester bonds|poly(A) RNA binding|",10,1.4,1.55,10,-0.3,1.05,-0.2,1.21,-1.21,0.508,0,0,-1.1,2
ENSMUSG00000047108,DNAJB7,"DnaJ (Hsp40) homolog, subfamily B, member 7",cellular_component|,biological_process|,chaperone binding|,10,-0.2,0.798,9,0.7,3.34,0.6,1.21,1.21,0.508,0,0,-1,1.8
ENSMUSG00000058099,NFAM1,Nfat activating molecule with ITAM motif 1,intracellular|plasma membrane|cell surface|membrane|integral component of membrane|integral component of membrane|membrane raft|,signal transduction|signal transduction|B cell differentiation|intracellular signal transduction|intracellular signal transduction|regulation of B cell differentiation|B cell receptor signaling pathway|positive regulation of B cell receptor signaling pathway|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|,transmembrane signaling receptor activity|transmembrane signaling receptor activity|,10,0.9,0.522,10,0.3,1.12,0.3,1.2,1.2,0.51,0,0,-0.3,2
ENSMUSG00000000632,SEZ6,seizure related gene 6,extracellular region|extracellular space|cytoplasm|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|cell junction|cell projection|neuronal cell body|dendritic spine|dendritic shaft|synapse|perinuclear region of cytoplasm|apical dendrite|,adult locomotory behavior|cerebellar Purkinje cell layer development|regulation of dendrite development|synapse maturation|regulation of excitatory postsynaptic membrane potential|regulation of protein kinase C signaling|positive regulation of dendrite development|negative regulation of dendrite development|,molecular_function|,10,0.3,1.18,10,0.1,0.129,0.3,1.2,1.2,0.51,0,0,-0.4,2
ENSMUSG00000055850,RNF181,ring finger protein 181,cellular_component|,protein autoubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.4,1.37,10,0.1,0.0742,0.3,1.2,1.2,0.51,0,0,-0.6,1.7
ENSMUSG00000026880,STOM,stomatin,extracellular space|cytoplasm|cytoskeleton|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|membrane|cytoplasmic vesicle|membrane raft|extracellular vesicular exosome|blood microparticle|,regulation of ion transmembrane transport|protein homooligomerization|regulation of acid-sensing ion channel activity|,protein binding|identical protein binding|protein homodimerization activity|,10,0.1,0.362,10,0.3,1.16,0.2,1.2,1.2,0.51,0,0,-0.8,1.7
ENSMUSG00000020189,OSBPL8,oxysterol binding protein-like 8,membrane|nuclear membrane|,transport|lipid transport|negative regulation of sequestering of triglyceride|negative regulation of cell migration|fat cell differentiation|positive regulation of insulin receptor signaling pathway|positive regulation of protein kinase B signaling|protein localization to nuclear pore|,protein binding|cholesterol binding|,10,-0.2,0.239,10,-0.2,1.05,-0.2,1.19,-1.19,0.512,0,0,-1.6,1
ENSMUSG00000015652,STEAP1,six transmembrane epithelial antigen of the prostate 1,endosome|plasma membrane|membrane|membrane|integral component of membrane|,transport|ion transport|iron ion homeostasis|oxidation-reduction process|,oxidoreductase activity|metal ion binding|,10,-0.3,1.67,10,0.2,0.87,-0.2,1.19,-1.19,0.512,0,0,-1.7,1
ENSMUSG00000044952,KCTD21,potassium channel tetramerisation domain containing 21,cellular_component|,transport|ion transport|biological_process|protein homooligomerization|,molecular_function|,8,-0.2,0.577,8,-0.2,0.706,-0.2,1.18,-1.18,0.514,0,0,-1.7,1.2
ENSMUSG00000020652,CENPO,centromere protein O,"chromosome, centromeric region|kinetochore|nucleus|chromosome|",biological_process|centromere complex assembly|,molecular_function|,10,0.2,0.354,9,-1.3,2.26,0.3,1.18,1.18,0.514,0,0,-2,1.2
ENSMUSG00000035764,FBXO45,F-box protein 45,plasma membrane|postsynaptic density|membrane|cell junction|synapse|postsynaptic membrane|,neuron migration|cellular response to DNA damage stimulus|multicellular organismal development|nervous system development|protein ubiquitination|protein ubiquitination|cerebral cortex radially oriented cell migration|cerebral cortex tangential migration|corticospinal tract morphogenesis|anterior commissure morphogenesis|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|innervation|synapse assembly involved in innervation|,protein binding|,10,-0.3,0.882,10,-0.2,0.398,-0.2,1.18,-1.18,0.514,0,0,-1.2,1.8
ENSMUSG00000015474,PPT2,palmitoyl-protein thioesterase 2,lysosome|extracellular vesicular exosome|,cellular protein modification process|,"palmitoyl-(protein) hydrolase activity|CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0,0,10,0.4,2.47,0.3,1.18,1.18,0.514,0,0,-0.7,1.8
ENSMUSG00000029165,AGBL5,ATP/GTP binding protein-like 5,nucleus|cytoplasm|cytosol|,proteolysis|protein deglutamylation|protein branching point deglutamylation|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|tubulin binding|hydrolase activity|metal ion binding|,10,-0.3,2.48,10,0.3,1.37,-0.3,1.18,-1.18,0.514,0,0,-1.4,1.2
ENSMUSG00000042385,GZMK,granzyme K,None,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.3,1.72,0.3,1.17,1.17,0.515,0,0,-1.4,1.4
ENSMUSG00000033177,TMPRSS7,transmembrane serine protease 7,plasma membrane|membrane|integral component of membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.5,2.39,10,0.1,0.152,-0.3,1.16,-1.16,0.517,0,0,-1.7,0.8
ENSMUSG00000053841,TXLNA,taxilin alpha,cytoplasm|membrane|,exocytosis|B cell activation|,syntaxin binding|,10,0.2,0.428,10,0.3,0.916,0.3,1.15,1.15,0.519,0,0,-1,1.8
ENSMUSG00000031438,RNF128,ring finger protein 128,cytoplasm|late endosome|endoplasmic reticulum|Golgi apparatus|cytoskeleton|membrane|integral component of membrane|,protein ubiquitination|negative regulation of cytokine biosynthetic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.5,2.7,-0.5,1.15,-1.15,0.519,0,0,-1.8,0.8
ENSMUSG00000032083,APOA1,apolipoprotein A-I,extracellular region|extracellular space|extracellular space|nucleus|cell surface|endocytic vesicle|cytoplasmic vesicle|very-low-density lipoprotein particle|high-density lipoprotein particle|discoidal high-density lipoprotein particle|spherical high-density lipoprotein particle|extracellular vesicular exosome|blood microparticle|,regulation of protein phosphorylation|endothelial cell proliferation|negative regulation of cytokine secretion involved in immune response|lipid metabolic process|phospholipid metabolic process|phosphatidylcholine biosynthetic process|cholesterol biosynthetic process|transport|lipid transport|G-protein coupled receptor signaling pathway|steroid metabolic process|cholesterol metabolic process|cholesterol metabolic process|cholesterol metabolic process|glucocorticoid metabolic process|negative regulation of tumor necrosis factor-mediated signaling pathway|positive regulation of cholesterol esterification|negative regulation of very-low-density lipoprotein particle remodeling|phospholipid transport|protein oxidation|peptidyl-methionine modification|lipid storage|regulation of intestinal cholesterol absorption|cholesterol transport|cholesterol transport|cholesterol transport|adrenal gland development|organ regeneration|regulation of Cdc42 protein signal transduction|cholesterol efflux|cholesterol efflux|cholesterol efflux|phospholipid efflux|negative regulation of heterotypic cell-cell adhesion|high-density lipoprotein particle assembly|lipoprotein metabolic process|lipoprotein biosynthetic process|lipoprotein biosynthetic process|cholesterol homeostasis|blood vessel endothelial cell migration|reverse cholesterol transport|negative regulation of interleukin-1 beta secretion|negative regulation of inflammatory response|protein stabilization|positive regulation of hydrolase activity|negative regulation of hydrolase activity|positive regulation of transferase activity|phospholipid homeostasis|negative regulation of lipase activity|negative regulation of cell adhesion molecule production|negative regulation of response to cytokine stimulus|triglyceride homeostasis|cholesterol import|,beta-amyloid binding|lipid transporter activity|lipid transporter activity|protein binding|phospholipid binding|phospholipid transporter activity|high-density lipoprotein particle binding|lipid binding|cholesterol binding|cholesterol transporter activity|cholesterol transporter activity|cholesterol transporter activity|enzyme binding|apolipoprotein receptor binding|apolipoprotein A-I receptor binding|identical protein binding|identical protein binding|lipase inhibitor activity|phosphatidylcholine-sterol O-acyltransferase activator activity|high-density lipoprotein particle receptor binding|lipoprotein particle binding|,10,-0.6,1.24,10,-0.7,0.137,-0.6,1.14,-1.14,0.521,0,0,-1.6,1.6
ENSMUSG00000046811,GLTPD2,glycolipid transfer protein domain containing 2,cellular_component|cytoplasm|,biological_process|glycolipid transport|,molecular_function|glycolipid transporter activity|glycolipid binding|,10,-0.4,1.71,10,-0.1,0.0854,-0.2,1.14,-1.14,0.521,0,0,-1.7,0.7
ENSMUSG00000028860,SYTL1,synaptotagmin-like 1,plasma membrane|plasma membrane|membrane|extrinsic component of plasma membrane|melanosome|,intracellular protein transport|exocytosis|exocytosis|vesicle-mediated transport|,protein binding|Rab GTPase binding|neurexin family protein binding|,10,0.6,1.36,10,-0.3,0.603,0.6,1.14,1.14,0.521,0,0,-0.7,2
ENSMUSG00000024713,PCSK5,proprotein convertase subtilisin/kexin type 5,extracellular region|extracellular space|Golgi apparatus|membrane|integral component of membrane|secretory granule|,kidney development|kidney development|signal peptide processing|proteolysis|heart development|female pregnancy|embryo implantation|anterior/posterior pattern specification|anterior/posterior pattern specification|protein processing|protein processing|peptide hormone processing|peptide hormone processing|viral life cycle|respiratory tube development|limb morphogenesis|cytokine biosynthetic process|peptide biosynthetic process|peptide biosynthetic process|embryonic digestive tract development|embryonic digestive tract development|embryonic skeletal system development|embryonic skeletal system development|,endopeptidase activity|serine-type endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|peptide binding|,10,-0.9,0.726,10,0.3,0.843,0.3,1.14,1.14,0.521,0,0,-1.9,0.8
ENSMUSG00000020869,LRRC59,leucine rich repeat containing 59,nucleus|endoplasmic reticulum|membrane|membrane|integral component of membrane|mitochondrial nucleoid|intracellular membrane-bounded organelle|,biological_process|,poly(A) RNA binding|,10,0.2,0.912,10,0.2,0.316,0.2,1.13,1.13,0.523,0,0,-0.8,1.7
ENSMUSG00000040875,OSBPL10,oxysterol binding protein-like 10,cellular_component|,transport|lipid transport|biological_process|,cholesterol binding|,10,-0.6,1.32,10,0.3,0.593,-0.2,1.13,-1.13,0.523,0,0,-1.8,1
ENSMUSG00000032309,FBXO22,F-box protein 22,nucleus|cytoplasm|,protein polyubiquitination|nucleocytoplasmic transport|cellular response to starvation|regulation of myotube differentiation|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|regulation of skeletal muscle fiber development|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,protein binding|,10,0.3,0.433,10,0.2,0.804,0.2,1.13,1.13,0.523,0,0,-1.3,1.4
ENSMUSG00000036752,TUBB4B,"tubulin, beta 4B class IVB",nucleus|cytoplasm|cytoskeleton|microtubule|protein complex|tubulin complex|extracellular vesicular exosome|,GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|double-stranded RNA binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,0.4,2.05,10,0.1,0.0338,0.3,1.13,1.13,0.523,0,0,-1,1.6
ENSMUSG00000024737,SLC15A3,"solute carrier family 15, member 3",lysosome|lysosomal membrane|membrane|integral component of membrane|,transport|oligopeptide transport|protein transport|peptide transport|,transporter activity|symporter activity|,10,0.2,0.815,10,0.1,0.49,0.2,1.12,1.12,0.525,0,0,-0.9,1.7
ENSMUSG00000024357,SIL1,endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae),extracellular space|endoplasmic reticulum|,transport|protein transport|,None,10,-0.3,0.427,10,-0.3,0.794,-0.3,1.12,-1.12,0.525,0,0,-1.7,0.8
ENSMUSG00000047379,B3GNT1,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1",Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,protein glycosylation|axon guidance|poly-N-acetyllactosamine biosynthetic process|,"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.535,10,0.8,1.07,0.2,1.12,1.12,0.525,0,0,-0.3,1.9
ENSMUSG00000045414,1190002N15RIK,RIKEN cDNA 1190002N15 gene,Golgi membrane|extracellular region|extracellular space|Golgi apparatus|COPI vesicle coat|COPI-coated vesicle|cytoplasmic vesicle|,"regulation of phosphatidylinositol 3-kinase signaling|vesicle targeting, to, from or within Golgi|cardiac muscle cell proliferation|",molecular_function|,10,0.4,3.01,10,0,0,0.3,1.11,1.11,0.526,0,0,-0.5,1.9
ENSMUSG00000022039,ADAM2,a disintegrin and metallopeptidase domain 2,acrosomal vesicle|cell surface|membrane|integral component of membrane|,proteolysis|cell adhesion|integrin-mediated signaling pathway|visual learning|adult behavior|,metalloendopeptidase activity|protein binding|metallopeptidase activity|zinc ion binding|,10,0.1,0.288,10,0.3,0.973,0.2,1.11,1.11,0.526,0,0,-0.8,1.7
ENSMUSG00000026697,MYOC,myocilin,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular space|cytoplasm|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial intermembrane space|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|cilium|membrane|extracellular matrix|cytoplasmic vesicle|node of Ranvier|myelin sheath abaxonal region|cell projection|extracellular vesicular exosome|mesaxon|,osteoblast differentiation|osteoblast differentiation|negative regulation of cell-matrix adhesion|positive regulation of phosphatidylinositol 3-kinase signaling|skeletal muscle hypertrophy|myelination in peripheral nervous system|positive regulation of cell migration|neuron projection development|negative regulation of Rho protein signal transduction|non-canonical Wnt signaling pathway via JNK cascade|ERBB2-ERBB3 signaling pathway|regulation of MAPK cascade|clustering of voltage-gated sodium channels|positive regulation of stress fiber assembly|negative regulation of stress fiber assembly|positive regulation of focal adhesion assembly|positive regulation of protein kinase B signaling|positive regulation of mitochondrial depolarization|bone development|positive regulation of substrate adhesion-dependent cell spreading|,fibronectin binding|frizzled binding|protein binding|receptor tyrosine kinase binding|myosin light chain binding|,10,-0.3,0.786,10,-0.2,0.483,-0.2,1.1,-1.1,0.528,0,0,-1.6,1
ENSMUSG00000049537,TECRL,"trans-2,3-enoyl-CoA reductase-like",cellular_component|cytoplasm|membrane|integral component of membrane|,lipid metabolic process|biological_process|oxidation-reduction process|,"molecular_function|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|enoyl-[acyl-carrier-protein] reductase activity|2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity|cis-2,3-dihydrodiol DDT dehydrogenase activity|trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity|cis-chlorobenzene dihydrodiol dehydrogenase activity|2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity|trans-1,2-dihydrodiolphenanthrene dehydrogenase activity|3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity|benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity|benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity|citronellyl-CoA dehydrogenase activity|menthone dehydrogenase activity|phthalate 3,4-cis-dihydrodiol dehydrogenase activity|cinnamate reductase activity|NADPH-dependent curcumin reductase activity|NADPH-dependent dihydrocurcumin reductase activity|",10,-0.1,0.443,10,-0.7,1.02,-0.2,1.1,-1.1,0.528,0,0,-2,0.5
ENSMUSG00000022763,AIFM3,"apoptosis-inducing factor, mitochondrion-associated 3",mitochondrion|mitochondrion|mitochondrial inner membrane|endoplasmic reticulum|,transport|apoptotic process|cell redox homeostasis|oxidation-reduction process|execution phase of apoptosis|,"N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|flavin adenine dinucleotide binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|epoxyqueuosine reductase activity|",10,0.2,0.693,10,0.2,0.502,0.2,1.1,1.1,0.528,0,0,-0.9,1.7
ENSMUSG00000029364,WSB2,WD repeat and SOCS box-containing 2,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,-0.3,1.43,10,-0.1,0.155,-0.2,1.09,-1.09,0.53,0,0,-1.5,1.1
ENSMUSG00000017307,ACOT8,acyl-CoA thioesterase 8,mitochondrion|peroxisome|peroxisomal matrix|,acyl-CoA metabolic process|acyl-CoA metabolic process|peroxisome organization|peroxisome fission|dicarboxylic acid catabolic process|,receptor binding|palmitoyl-CoA hydrolase activity|hydrolase activity|choloyl-CoA hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|medium-chain acyl-CoA hydrolase activity|,10,-0.3,0.447,10,-0.2,0.801,-0.3,1.09,-1.09,0.53,0,0,-1.6,1
ENSMUSG00000049866,ARL4C,ADP-ribosylation factor-like 4C,intracellular|cytoplasm|plasma membrane|membrane|cell projection|,transport|small GTPase mediated signal transduction|endocytic recycling|,nucleotide binding|GTP binding|alpha-tubulin binding|,10,0.2,0.625,10,0.2,0.562,0.2,1.09,1.09,0.53,0,0,-0.9,1.7
ENSMUSG00000003309,AP1M2,"adaptor protein complex AP-1, mu 2 subunit",Golgi apparatus|trans-Golgi network|membrane|clathrin adaptor complex|cytoplasmic vesicle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,None,10,-0.2,0.463,10,-0.3,0.794,-0.2,1.09,-1.09,0.53,0,0,-1.4,1.4
ENSMUSG00000024127,PREPL,prolyl endopeptidase-like,cytoplasm|Golgi apparatus|cytoskeleton|,proteolysis|,serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|serine-type exopeptidase activity|,10,-0.1,0.268,10,0.2,1.35,0.2,1.08,1.08,0.532,0,0,-1.6,1.2
ENSMUSG00000044938,KLHL31,kelch-like 31,cellular_component|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,9,-0.6,2.5,9,0,0,-0.4,1.08,-1.08,0.532,0,0,-1.9,0.6
ENSMUSG00000034459,IFIT1,interferon-induced protein with tetratricopeptide repeats 1,cytoplasm|,immune system process|response to virus|cellular response to interferon-alpha|cellular response to interferon-beta|innate immune response|defense response to virus|,RNA binding|protein binding|,10,0.3,1.02,10,0.2,0.207,0.2,1.07,1.07,0.534,0,0,-1,1.8
ENSMUSG00000024566,ATP9B,"ATPase, class II, type 9B",Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|perinuclear region of cytoplasm|,cation transport|phospholipid transport|establishment of protein localization to Golgi|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,9,-0.4,1.93,9,1,0.594,-0.2,1.07,-1.07,0.534,0,0,-1.4,1.7
ENSMUSG00000021190,LGMN,legumain,lysosome|lysosome|late endosome|apical part of cell|,renal system process|proteolysis|proteolysis|proteolysis|response to acidity|receptor catabolic process|negative regulation of multicellular organism growth|negative regulation of neuron apoptotic process|proteolysis involved in cellular protein catabolic process|negative regulation of ERBB signaling pathway|,cysteine-type endopeptidase activity|peptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.4,1.17,10,0.1,0.357,0.2,1.07,1.07,0.534,0,0,-1.1,1.6
ENSMUSG00000025754,AGBL1,ATP/GTP binding protein-like 1,cytoplasm|,proteolysis|C-terminal protein deglutamylation|protein side chain deglutamylation|,carboxypeptidase activity|metallocarboxypeptidase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|tubulin binding|hydrolase activity|metal ion binding|,10,-1.3,4.38,10,0,0,-1.3,1.07,-1.07,0.534,0,0,-2,0.4
ENSMUSG00000037563,RPS16,ribosomal protein S16,ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,rRNA processing|translation|ribosomal small subunit biogenesis|,RNA binding|structural constituent of ribosome|poly(A) RNA binding|,4,0.7,0.924,3,0.2,0.543,0.3,1.06,1.06,0.536,0,0,-1.7,1.8
ENSMUSG00000040188,SCAMP2,secretory carrier membrane protein 2,nucleus|endosome|Golgi apparatus|membrane|integral component of membrane|transport vesicle|trans-Golgi network membrane|intracellular membrane-bounded organelle|recycling endosome membrane|extracellular vesicular exosome|,transport|protein transport|,None,10,0.6,1.32,10,-0.1,0.41,0.5,1.05,1.05,0.538,0,0,-1,1.7
ENSMUSG00000032925,ITGBL1,"integrin, beta-like 1",cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.3,2.26,10,0.5,1.47,-0.3,1.04,-1.04,0.54,0,0,-1.3,1.5
ENSMUSG00000090173,FBXW10,F-box and WD-40 domain protein 10,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0784,10,0.2,1.14,0.2,1.02,1.02,0.544,0,0,-1.4,1.5
ENSMUSG00000024134,SIX2,sine oculis-related homeobox 2,nucleus|,"metanephros development|kidney development|kidney development|chondrocyte differentiation|regulation of transcription, DNA-templated|protein import into nucleus|multicellular organismal development|mesodermal cell fate specification|cell proliferation|regulation of ossification|regulation of chondrocyte differentiation|middle ear morphogenesis|negative regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|embryonic digestive tract morphogenesis|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|canonical Wnt signaling pathway|nephron morphogenesis|mesenchymal stem cell maintenance involved in nephron morphogenesis|mesenchymal cell differentiation involved in kidney development|regulation of branching involved in ureteric bud morphogenesis|positive regulation of chondrocyte proliferation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein complex binding|sequence-specific DNA binding|,10,-0.3,0.0471,10,0.3,2.51,0.2,1.02,1.02,0.544,0,0,-1.2,1.5
ENSMUSG00000027434,NKX2-2,NK2 homeobox 2,intracellular|nucleus|nucleus|,"type B pancreatic cell development|type B pancreatic cell development|pancreatic A cell fate commitment|pancreatic A cell fate commitment|type B pancreatic cell fate commitment|pancreatic PP cell fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|smoothened signaling pathway|multicellular organismal development|nervous system development|oligodendrocyte development|spinal cord motor neuron differentiation|spinal cord oligodendrocyte cell differentiation|spinal cord oligodendrocyte cell differentiation|spinal cord oligodendrocyte cell fate specification|cell differentiation|endocrine pancreas development|regulation of cell differentiation|positive regulation of cell differentiation|negative regulation of neuron differentiation|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|cell development|digestive tract development|neuron fate specification|neuron fate specification|astrocyte differentiation|positive regulation of oligodendrocyte differentiation|positive regulation of sequence-specific DNA binding transcription factor activity|ventral spinal cord interneuron fate determination|",core promoter proximal region DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|transcription factor binding|sequence-specific DNA binding|,10,-0.2,1.81,10,0.1,0.244,-0.2,1.02,-1.02,0.544,0,0,-1.9,0.6
ENSMUSG00000052271,BHLHA15,"basic helix-loop-helix family, member a15",intracellular|cell|nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|mitochondrial calcium ion transport|Golgi organization|G-protein coupled receptor signaling pathway|cell-cell signaling|calcium-mediated signaling|glucose homeostasis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|intracellular distribution of mitochondria|cell maturation|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|protein homodimerization activity|protein dimerization activity|,10,0.2,0.351,10,0.2,0.753,0.2,1.02,1.02,0.544,0,0,-0.7,1.9
ENSMUSG00000047884,KLK9,kallikrein related-peptidase 9,cellular_component|,proteolysis|biological_process|,molecular_function|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,-0.4,2.45,10,0.2,0.217,-0.3,1.02,-1.02,0.544,0,0,-1.6,1
ENSMUSG00000046258,ADAM29,a disintegrin and metallopeptidase domain 29,cellular_component|membrane|integral component of membrane|,proteolysis|biological_process|,molecular_function|metalloendopeptidase activity|metallopeptidase activity|zinc ion binding|,10,-0.3,1.36,10,-0.1,0.202,-0.2,1.01,-1.01,0.546,0,0,-1.7,1
ENSMUSG00000050796,B3GALT6,"UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6",Golgi apparatus|Golgi medial cisterna|Golgi medial cisterna|membrane|membrane|integral component of membrane|,glycosaminoglycan biosynthetic process|glycosaminoglycan biosynthetic process|protein glycosylation|,"galactosyltransferase activity|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|UDP-galactosyltransferase activity|galactosylxylosylprotein 3-beta-galactosyltransferase activity|",10,0.5,1.98,10,-0.1,0.14,0.5,1.01,1.01,0.546,0,0,-0.7,1.8
ENSMUSG00000032295,MAN2C1,"mannosidase, alpha, class 2C, member 1",None,carbohydrate metabolic process|mannose metabolic process|metabolic process|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-mannosidase activity|zinc ion binding|mannosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|metal ion binding|",10,0.4,1.04,10,0.2,0.497,0.3,1.01,1.01,0.546,0,0,-1.3,1.6
ENSMUSG00000074896,IFIT3,interferon-induced protein with tetratricopeptide repeats 3,cytoplasm|mitochondrion|,immune system process|cellular response to interferon-alpha|cellular response to interferon-beta|innate immune response|defense response to virus|,protein binding|identical protein binding|,10,0.1,0.292,10,0.4,1.12,0.2,1.01,1.01,0.546,0,0,-1,1.7
ENSMUSG00000091722,SIAH3,seven in absentia homolog 3 (Drosophila),cellular_component|,biological_process|,"molecular_function|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.142,10,-0.4,1.17,-0.3,1,-1,0.548,0,0,-1.8,0.7
ENSMUSG00000024300,MYO1F,myosin IF,cell|myosin complex|cortical actin cytoskeleton|filamentous actin|,neutrophil mediated immunity|negative regulation of cell adhesion|positive regulation of cell migration|regulation of actin cytoskeleton organization|neutrophil degranulation|regulation of innate immune response|defense response to Gram-positive bacterium|,nucleotide binding|molecular_function|motor activity|actin binding|calmodulin binding|ATP binding|,10,-0.3,0.645,10,-0.2,0.487,-0.2,1,-1,0.548,0,0,-1.5,1.3
ENSMUSG00000042178,ARMC5,armadillo repeat containing 5,cellular_component|,biological_process|,molecular_function|,10,0.5,0.836,10,0.2,0.773,0.3,1,1,0.548,0,0,-1.2,1.5
ENSMUSG00000051853,ARF3,ADP-ribosylation factor 3,intracellular|cytoplasm|Golgi apparatus|extracellular vesicular exosome|,transport|small GTPase mediated signal transduction|protein transport|vesicle-mediated transport|,nucleotide binding|GTP binding|,10,-0.6,2.24,10,0,0,-0.2,1,-1,0.548,0,0,-2,0.7
ENSMUSG00000036432,SIAH2,seven in absentia 2,nucleus|cytoplasm|early endosome|cytosol|neuron projection|neuronal cell body|,ubiquitin-dependent protein catabolic process|apoptotic process|cell cycle|multicellular organismal development|protein ubiquitination|regulation of protein ubiquitination|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular protein catabolic process|negative regulation of canonical Wnt signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin conjugating enzyme binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.4,1.5,-0.3,0.99,-0.99,0.55,0,0,-1.3,1.7
ENSMUSG00000052544,ST6GALNAC3,"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3",Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|glycosylceramide metabolic process|glycosphingolipid metabolic process|glycoprotein metabolic process|sialylation|,"sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.439,10,0.3,0.631,0.2,0.975,0.975,0.554,0,0,-0.6,1.9
ENSMUSG00000047215,RPL9,ribosomal protein L9,intracellular|nucleus|nucleolus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|rRNA binding|,3,0.4,1.23,2,0.1,0.0761,0.4,0.975,0.975,0.554,0,0,-1.9,1.7
ENSMUSG00000048775,SERPINB13,"serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13",extracellular region|extracellular space|cytoplasm|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.1,0.0587,10,0.5,2.01,0.3,0.975,0.975,0.554,0,0,-1.5,1.5
ENSMUSG00000038534,OSBPL7,oxysterol binding protein-like 7,autophagic vacuole|cytosol|plasma membrane|perinuclear endoplasmic reticulum|,transport|lipid transport|cellular response to cholesterol|positive regulation of proteasomal protein catabolic process|,cholesterol binding|,10,0.2,0.802,10,0.2,0.254,0.2,0.973,0.973,0.554,0,0,-0.9,1.8
ENSMUSG00000019122,CCL9,chemokine (C-C motif) ligand 9,extracellular region|extracellular space|,chemotaxis|immune response|,cytokine activity|chemokine activity|,10,0.1,0.297,10,-0.3,1.39,-0.2,0.973,-0.973,0.554,0,0,-1.3,1.5
ENSMUSG00000003779,KIF20A,kinesin family member 20A,cytoplasm|Golgi apparatus|spindle|cytoskeleton|kinesin complex|microtubule|,cytokinesis|microtubule bundle formation|transport|microtubule-based movement|protein transport|,nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|protein kinase binding|,10,-0.6,2,10,0.2,0.227,-0.5,0.971,-0.971,0.554,0,0,-1.8,0.8
ENSMUSG00000029110,RNF4,ring finger protein 4,nucleus|nucleus|nucleoplasm|cytoplasm|cytoplasm|PML body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|response to arsenic-containing substance|protein autoubiquitination|protein K63-linked ubiquitination|protein K48-linked ubiquitination|protein K11-linked ubiquitination|protein K6-linked ubiquitination|regulation of spindle assembly|regulation of kinetochore assembly|","DNA binding|ubiquitin-protein transferase activity|protein binding|transcription factor binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|estrogen receptor binding|nucleosome binding|SUMO polymer binding|progesterone receptor binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|androgen receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",8,-0.2,0.842,8,-0.1,0.251,-0.2,0.97,-0.97,0.554,0,0,-1.7,1.2
ENSMUSG00000008438,ADAM21,a disintegrin and metallopeptidase domain 21,membrane|integral component of membrane|axon|neuron projection|neuronal cell body|,proteolysis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.2,0.379,10,-0.4,1,-0.2,0.962,-0.962,0.556,0,0,-1.6,1.2
ENSMUSG00000024664,FADS3,fatty acid desaturase 3,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|transport|biological_process|oxidation-reduction process|,"iron ion binding|acyl-CoA desaturase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water|heme binding|",9,-0.1,0.435,9,-0.3,0.963,-0.2,0.961,-0.961,0.556,0,0,-1.1,1.8
ENSMUSG00000032952,AP4B1,"adaptor-related protein complex AP-4, beta 1",Golgi apparatus|trans-Golgi network|trans-Golgi network|coated pit|membrane|membrane coat|clathrin adaptor complex|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,protein transporter activity|,10,-0.2,0.948,10,-0.1,0.23,-0.2,0.96,-0.96,0.556,0,0,-1.6,1.1
ENSMUSG00000020376,RNF130,ring finger protein 130,nucleus|cytoplasm|membrane|integral component of membrane|,apoptotic process|programmed cell death|protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.3,1.53,0.3,0.959,0.959,0.557,0,0,-0.5,1.9
ENSMUSG00000055561,SPINK5,"serine peptidase inhibitor, Kazal type 5",extracellular region|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|cytosol|cell cortex|perinuclear region of cytoplasm|extracellular vesicular exosome|epidermal lamellar body|,epidermal cell differentiation|negative regulation of endopeptidase activity|regulation of cell adhesion|negative regulation of proteolysis|negative regulation of serine-type peptidase activity|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.5,0.765,9,-1.5,2.81,-1.4,0.959,-0.959,0.557,0,0,-3,0.4
ENSMUSG00000029470,P2RX4,"purinergic receptor P2X, ligand-gated ion channel 4",integral component of nuclear inner membrane|lysosomal membrane|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|axon|dendrite|neuronal cell body|terminal bouton|dendritic spine|apical part of cell|synapse|perinuclear region of cytoplasm|extracellular vesicular exosome|,regulation of sodium ion transport|nitric oxide biosynthetic process|nitric oxide biosynthetic process|transport|ion transport|cation transport|cation transport|calcium ion transport|signal transduction|regulation of blood pressure|positive regulation of calcium ion transport into cytosol|negative regulation of cardiac muscle hypertrophy|neuronal action potential|sensory perception of pain|response to ATP|ion transmembrane transport|ion transmembrane transport|response to fluid shear stress|purinergic nucleotide receptor signaling pathway|purinergic nucleotide receptor signaling pathway|vasodilation|positive regulation of calcium-mediated signaling|protein homooligomerization|membrane depolarization|regulation of cardiac muscle contraction|relaxation of cardiac muscle|regulation of excitatory postsynaptic membrane potential|cellular response to ATP|apoptotic signaling pathway|,purinergic nucleotide receptor activity|purinergic nucleotide receptor activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|receptor binding|ion channel activity|copper ion binding|ATP binding|drug binding|zinc ion binding|cadherin binding|,10,-0.2,0.296,10,0.3,1.43,0.2,0.954,0.954,0.558,0,0,-1.1,1.7
ENSMUSG00000023272,CRELD2,cysteine-rich with EGF-like domains 2,extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|,biological_process|,calcium ion binding|,10,0.3,0.278,10,0.2,0.803,0.2,0.95,0.95,0.559,0,0,-0.9,1.7
ENSMUSG00000019429,FFAR3,free fatty acid receptor 3,plasma membrane|plasma membrane|membrane|integral component of membrane|,regulation of heart rate by chemical signal|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|regulation of norepinephrine secretion|glucose homeostasis|positive regulation of action potential|cellular response to fatty acid|cellular response to fatty acid|regulation of peptide hormone secretion|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|lipid binding|,10,0.3,0.106,10,0.4,1.01,0.4,0.947,0.947,0.559,0,0,-0.5,1.9
ENSMUSG00000073399,TRIM40,tripartite motif-containing 40,intracellular|IkappaB kinase complex|,negative regulation of cell growth|negative regulation of NF-kappaB transcription factor activity|negative regulation of protein catabolic process|protein neddylation|negative regulation of protein localization to nucleus|,zinc ion binding|metal ion binding|,10,0.1,0.275,10,0.4,1.11,0.2,0.945,0.945,0.56,0,0,-0.5,1.9
ENSMUSG00000063049,ING2,"inhibitor of growth family, member 2",nucleus|Sin3 complex|CCAAT-binding factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|male meiosis I|spermatogenesis|spermatid development|negative regulation of cell proliferation|chromatin modification|sperm motility|positive regulation of transforming growth factor beta receptor signaling pathway|regulation of growth|positive regulation of apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|male germ-line stem cell asymmetric division|seminiferous tubule development|negative regulation of apoptotic signaling pathway|",DNA binding|chromatin binding|zinc ion binding|protein complex binding|methylated histone binding|phosphatidylinositol binding|metal ion binding|,10,0.2,0.361,10,0.2,0.665,0.2,0.942,0.942,0.561,0,0,-1.1,1.6
ENSMUSG00000041241,MUL1,mitochondrial ubiquitin ligase activator of NFKB 1,nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrial outer membrane|peroxisome|membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|,mitochondrial fission|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|mitochondrion organization|activation of JUN kinase activity|negative regulation of mitochondrial fusion|protein ubiquitination|negative regulation of cell growth|positive regulation of protein sumoylation|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of innate immune response|negative regulation of defense response to virus by host|protein stabilization|mitochondrion localization|negative regulation of protein kinase B signaling|negative regulation of type I interferon-mediated signaling pathway|cellular response to exogenous dsRNA|negative regulation of chemokine (C-C motif) ligand 5 production|positive regulation of mitochondrial fission|regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|,"ubiquitin-protein transferase activity|signal transducer activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|ubiquitin protein ligase binding|identical protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.7,2.18,10,0.4,0.383,-0.2,0.942,-0.942,0.561,0,0,-1.8,0.9
ENSMUSG00000033793,ATP6V1H,"ATPase, H+ transporting, lysosomal V1 subunit H","vacuolar proton-transporting V-type ATPase, V1 domain|lysosomal membrane|extracellular vesicular exosome|",transport|ion transport|endocytosis|ATP hydrolysis coupled proton transport|proton transport|,"hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|proton-transporting ATPase activity, rotational mechanism|",10,-1.1,0.499,10,-0.3,1.13,-0.3,0.935,-0.935,0.562,0,0,-2,0.5
ENSMUSG00000021583,ERAP1,endoplasmic reticulum aminopeptidase 1,extracellular region|extracellular space|cytoplasm|endoplasmic reticulum|endoplasmic reticulum lumen|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,immune system process|proteolysis|proteolysis|membrane protein ectodomain proteolysis|positive regulation of angiogenesis|,aminopeptidase activity|aminopeptidase activity|interleukin-6 receptor binding|tumor necrosis factor receptor binding|peptidase activity|metalloexopeptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0.4,2.64,0.3,0.934,0.934,0.562,0,0,-0.6,1.8
ENSMUSG00000010047,HYAL2,hyaluronoglucosaminidase 2,Golgi membrane|Golgi membrane|cytoplasm|lysosome|cytosol|plasma membrane|microvillus|cell surface|cell surface|membrane|cytoplasmic membrane-bounded vesicle|apical plasma membrane|endocytic vesicle|anchored component of membrane|anchored component of external side of plasma membrane|cytoplasmic vesicle|membrane raft|membrane raft|anchored component of plasma membrane|anchored component of plasma membrane|perinuclear region of cytoplasm|,response to reactive oxygen species|hematopoietic progenitor cell differentiation|carbohydrate metabolic process|glycosaminoglycan catabolic process|metabolic process|response to virus|response to virus|multicellular organismal aging|negative regulation of fibroblast migration|fusion of virus membrane with host plasma membrane|transformation of host cell by virus|hyaluronan catabolic process|hyaluronan catabolic process|negative regulation of cell growth|monocyte activation|monocyte activation|positive regulation of protein import into nucleus|negative regulation of MAP kinase activity|cellular response to fibroblast growth factor stimulus|positive regulation of transcription from RNA polymerase II promoter|viral entry into host cell|skeletal system morphogenesis|positive regulation of inflammatory response|positive regulation of inflammatory response|defense response to virus|negative regulation of protein kinase B signaling|multicellular organismal iron ion homeostasis|negative regulation of protein tyrosine kinase activity|cellular response to interleukin-1|cellular response to UV-B|cellular response to transforming growth factor beta stimulus|cellular response to transforming growth factor beta stimulus|positive regulation of interleukin-8 secretion|positive regulation of interleukin-8 secretion|positive regulation of interleukin-6 secretion|positive regulation of interleukin-6 secretion|positive regulation of extrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway|,"RNA polymerase II transcription coactivator activity|virus receptor activity|catalytic activity|hyalurononglucosaminidase activity|hyaluronic acid binding|hyaluronic acid binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|enzyme binding|enzyme binding|receptor signaling protein tyrosine kinase inhibitor activity|receptor tyrosine kinase binding|hyaluronoglucuronidase activity|transforming growth factor beta binding|",10,0.4,1.44,10,1,0.0866,0.2,0.93,0.93,0.563,0,0,-0.3,2
ENSMUSG00000067586,S1PR3,sphingosine-1-phosphate receptor 3,plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,cytokine production|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|regulation of interleukin-1 beta production|negative regulation of establishment of endothelial barrier|,signal transducer activity|G-protein coupled receptor activity|integrin binding|sphingosine-1-phosphate receptor activity|,10,-0.2,0.207,10,-0.3,0.89,-0.3,0.924,-0.924,0.565,0,0,-1.7,1
ENSMUSG00000025479,CYP2E1,"cytochrome P450, family 2, subfamily e, polypeptide 1",Golgi membrane|mitochondrion|endoplasmic reticulum|membrane|intrinsic component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|,triglyceride metabolic process|xenobiotic metabolic process|steroid metabolic process|monoterpenoid metabolic process|drug metabolic process|heterocycle metabolic process|oxidation-reduction process|oxidation-reduction process|,"monooxygenase activity|monooxygenase activity|iron ion binding|3-(3-hydroxyphenyl)propionate hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|4-chlorobenzaldehyde oxidase activity|3,5-xylenol methylhydroxylase activity|phenylacetate hydroxylase activity|4-nitrophenol 4-monooxygenase activity|dimethyl sulfide monooxygenase activity|alpha-pinene monooxygenase [NADH] activity|phenanthrene 9,10-monooxygenase activity|1-hydroxy-2-naphthoate hydroxylase activity|toluene 4-monooxygenase activity|xylene monooxygenase activity|dibenzothiophene monooxygenase activity|6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|chlorophenol 4-monooxygenase activity|carbon disulfide oxygenase activity|toluene 2-monooxygenase activity|1-hydroxy-2-oxolimonene 1,2-monooxygenase activity|phenanthrene 1,2-monooxygenase activity|tetrahydrofuran hydroxylase activity|styrene monooxygenase activity|toluene-4-sulfonate monooxygenase activity|toluene-sulfonate methyl-monooxygenase activity|3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity|2-hydroxy-phenylacetate hydroxylase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity|phenanthrene 3,4-monooxygenase activity|toluene 3-monooxygenase activity|4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity|limonene monooxygenase activity|enzyme binding|heme binding|2-methylnaphthalene hydroxylase activity|1-methylnaphthalene hydroxylase activity|bisphenol A hydroxylase A activity|salicylate 5-hydroxylase activity|isobutylamine N-hydroxylase activity|branched-chain dodecylbenzene sulfonate monooxygenase activity|3-HSA hydroxylase activity|4-hydroxypyridine-3-hydroxylase activity|2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity|6-hydroxynicotinate 3-monooxygenase activity|metal ion binding|tocotrienol omega-hydroxylase activity|thalianol hydroxylase activity|",10,-0.1,0.463,10,-0.2,0.559,-0.2,0.923,-0.923,0.565,0,0,-1.7,0.9
ENSMUSG00000061313,DDHD2,DDHD domain containing 2,cytoplasm|Golgi apparatus|microtubule organizing center|,lipid metabolic process|biological_process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|metal ion binding|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.3,1.32,10,0,0,-0.2,0.921,-0.921,0.565,0,0,-1.5,1.2
ENSMUSG00000033615,CPLX1,complexin 1,cell|cytoplasm|dendrite|SNARE complex|neuronal cell body|protein complex|synapse|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex|,transport|neurotransmitter transport|exocytosis|synaptic vesicle exocytosis|synaptic vesicle exocytosis|insulin secretion|,SNARE binding|neurotransmitter transporter activity|syntaxin-1 binding|syntaxin binding|,10,-0.3,1.39,10,0.4,0.913,-0.2,0.92,-0.92,0.566,0,0,-1.2,1.5
ENSMUSG00000040125,GPR26,G protein-coupled receptor 26,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,-0.3,2.07,-0.3,0.92,-0.92,0.566,0,0,-1.7,0.9
ENSMUSG00000027276,JAG1,jagged 1,plasma membrane|plasma membrane|membrane|integral component of membrane|apical part of cell|,blood vessel remodeling|morphogenesis of an epithelial sheet|T cell mediated immunity|pulmonary valve morphogenesis|cardiac right ventricle morphogenesis|cell communication|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|organ morphogenesis|response to muramyl dipeptide|aorta morphogenesis|regulation of cell proliferation|auditory receptor cell differentiation|auditory receptor cell differentiation|camera-type eye development|negative regulation of cell differentiation|negative regulation of cell differentiation|negative regulation of fat cell differentiation|positive regulation of myeloid cell differentiation|negative regulation of neuron differentiation|positive regulation of osteoblast differentiation|positive regulation of Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|inner ear development|cardiac septum morphogenesis|ciliary body morphogenesis|pulmonary artery morphogenesis|cardiac neural crest cell development involved in outflow tract morphogenesis|Notch signaling involved in heart development|Notch signaling involved in heart development|endocardial cushion cell development|negative regulation of stem cell differentiation|,Notch binding|calcium ion binding|protein binding|,9,-0.2,1.49,9,0,0,-0.2,0.918,-0.918,0.566,0,0,-1.7,1.1
ENSMUSG00000027429,SEC23B,SEC23B (S. cerevisiae),endoplasmic reticulum|Golgi apparatus|endomembrane system|membrane|COPII vesicle coat|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,protein binding|zinc ion binding|,10,-0.1,0.287,10,-0.5,1.12,-0.3,0.918,-0.918,0.566,0,0,-1.9,0.5
ENSMUSG00000038187,BTBD10,BTB (POZ) domain containing 10,nucleus|,biological_process|,molecular_function|,10,0.7,3.29,10,-0.1,0.112,0.2,0.913,0.913,0.567,0,0,-0.6,1.9
ENSMUSG00000021451,SEMA4D,"sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D",extracellular space|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|positive regulation of protein phosphorylation|negative regulation of cell adhesion|multicellular organismal development|nervous system development|regulation of cell shape|negative regulation of alkaline phosphatase activity|negative regulation of alkaline phosphatase activity|positive regulation of phosphatidylinositol 3-kinase signaling|cell differentiation|positive regulation of cell migration|positive regulation of cell migration|regulation of cell projection organization|positive regulation of Rho GTPase activity|positive regulation of Rho GTPase activity|ossification involved in bone maturation|ossification involved in bone maturation|negative regulation of osteoblast differentiation|positive regulation of collateral sprouting|regulation of dendrite morphogenesis|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of peptidyl-tyrosine phosphorylation|positive regulation of axonogenesis|positive regulation of axonogenesis|leukocyte aggregation|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis|,receptor activity|transmembrane signaling receptor activity|receptor binding|receptor binding|semaphorin receptor binding|semaphorin receptor binding|,10,0.2,0.836,10,0.2,0.149,0.2,0.908,0.908,0.568,0,0,-1.5,1.5
ENSMUSG00000024776,STAMBPL1,STAM binding protein like 1,membrane|,proteolysis|biological_process|,molecular_function|peptidase activity|metallopeptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|metal ion binding|,10,-0.6,2.66,10,0.2,0.599,-0.5,0.908,-0.908,0.568,0,0,-1.6,1.2
ENSMUSG00000044430,KLK12,kallikrein related-peptidase 12,extracellular vesicular exosome|,proteolysis|,peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,0.497,10,-0.1,0.494,-0.1,0.9,-0.9,0.57,0,0,-1.4,1.4
ENSMUSG00000041794,MYRIP,myosin VIIA and Rab interacting protein,exocyst|photoreceptor outer segment|cell|cytoplasm|actin cytoskeleton|apical plasma membrane|secretory granule membrane|dense core granule|cytoplasmic vesicle|melanosome|synapse|perinuclear region of cytoplasm|,intracellular protein transport|vesicle transport along actin filament|positive regulation of insulin secretion|,actin binding|protein binding|myosin binding|myosin binding|Rab GTPase binding|Rab GTPase binding|metal ion binding|protein kinase A binding|protein kinase A binding|,10,-0.6,0.958,10,-0.7,0.0456,-0.7,0.898,-0.898,0.57,0,0,-2,0.3
ENSMUSG00000051936,PRSS58,"protease, serine 58",cellular_component|extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.3,2.33,10,-1.9,2.99,-0.3,0.894,-0.894,0.571,0,0,-3,0.3
ENSMUSG00000020143,DOCK2,dedicator of cyto-kinesis 2,cytoplasm|cytoskeleton|membrane|membrane|extracellular vesicular exosome|,membrane raft polarization|establishment of T cell polarity|immunological synapse formation|myeloid dendritic cell activation involved in immune response|chemotaxis|cytoskeleton organization|small GTPase mediated signal transduction|positive regulation of Rac GTPase activity|positive regulation of Rac protein signal transduction|T cell proliferation|T cell activation|macropinocytosis|positive thymic T cell selection|negative thymic T cell selection|alpha-beta T cell activation|alpha-beta T cell proliferation|positive regulation of phagocytosis|,guanyl-nucleotide exchange factor activity|Rac GTPase activator activity|Rac guanyl-nucleotide exchange factor activity|T cell receptor binding|,10,0.6,2.45,10,0,0,0.2,0.889,0.889,0.572,0,0,-0.8,1.8
ENSMUSG00000031981,CAPN9,calpain 9,intracellular|cytoplasm|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|,10,-0.4,2.2,10,0.2,0.483,-0.3,0.886,-0.886,0.573,0,0,-1.5,1.4
ENSMUSG00000033508,ASPRV1,"aspartic peptidase, retroviral-like 1",membrane|integral component of membrane|,proteolysis|protein processing|protein processing|skin development|,"aspartic-type endopeptidase activity|aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|",10,-0.7,1.09,10,-0.2,0.373,0.2,0.885,0.885,0.573,0,0,-1.6,1.4
ENSMUSG00000038383,PIGU,"phosphatidylinositol glycan anchor biosynthesis, class U",endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|GPI-anchor transamidase complex|,GPI anchor biosynthetic process|attachment of GPI anchor to protein|regulation of JAK-STAT cascade|,GPI-anchor transamidase activity|GPI anchor binding|,9,-0.1,0.196,9,-0.7,1.08,-0.6,0.879,-0.879,0.575,0,0,-1.9,0.6
ENSMUSG00000045427,HNRNPH2,heterogeneous nuclear ribonucleoprotein H2,nucleus|membrane|ribonucleoprotein complex|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.3,0.122,10,0.3,1.76,0.2,0.874,0.874,0.576,0,0,-1.3,1.4
ENSMUSG00000052974,CYP2F2,"cytochrome P450, family 2, subfamily f, polypeptide 2",endoplasmic reticulum|membrane|intracellular membrane-bounded organelle|,response to toxic substance|naphthalene metabolic process|naphthalene metabolic process|trichloroethylene metabolic process|oxidation-reduction process|,"monooxygenase activity|iron ion binding|2-octaprenyl-6-methoxyphenol hydroxylase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen|dibenzothiophene-5,5-dioxide monooxygenase activity|oxygen binding|heme binding|pyrrole-2-carboxylate monooxygenase activity|metal ion binding|",9,-0.2,0.409,9,-0.2,0.539,-0.2,0.87,-0.87,0.577,0,0,-1.8,0.9
ENSMUSG00000053687,DPEP2,dipeptidase 2,cellular_component|membrane|anchored component of membrane|,proteolysis|,peptidase activity|metalloexopeptidase activity|metallopeptidase activity|exopeptidase activity|dipeptidyl-peptidase activity|hydrolase activity|dipeptidase activity|metal ion binding|,10,-0.5,1.03,10,0.3,1.51,-0.4,0.869,-0.869,0.577,0,0,-1.7,1
ENSMUSG00000054814,USP46,ubiquitin specific peptidase 46,cellular_component|,"behavioral fear response|proteolysis|ubiquitin-dependent protein catabolic process|behavior|adult feeding behavior|protein deubiquitination|regulation of synaptic transmission, GABAergic|behavioral response to ethanol|righting reflex|",ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,-0.3,0.264,10,-0.2,0.686,-0.2,0.865,-0.865,0.578,0,0,-1.4,1.5
ENSMUSG00000025221,KCNIP2,Kv channel-interacting protein 2,cytoplasm|plasma membrane|voltage-gated potassium channel complex|membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|clustering of voltage-gated potassium channels|potassium ion export|potassium ion transmembrane transport|membrane repolarization|,voltage-gated ion channel activity|A-type (transient outward) potassium channel activity|potassium channel activity|calcium ion binding|potassium channel regulator activity|identical protein binding|ion channel binding|metal ion binding|protein N-terminus binding|,10,0.1,0.326,10,0.2,0.783,0.2,0.865,0.865,0.578,0,0,-1,1.7
ENSMUSG00000036019,TMTC2,transmembrane and tetratricopeptide repeat containing 2,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,0.804,10,-0.2,0.751,-0.2,0.864,-0.864,0.578,0,0,-1.2,1.6
ENSMUSG00000039208,METRNL,"meteorin, glial cell differentiation regulator-like",extracellular region|extracellular space|extracellular vesicular exosome|,fat cell differentiation|,molecular_function|,10,0,0,10,0.3,1.58,0.2,0.852,0.852,0.581,0,0,-1,1.6
ENSMUSG00000050747,TRIM15,tripartite motif-containing 15,cellular_component|,positive regulation of type I interferon production|innate immune response|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of RIG-I signaling pathway|negative regulation of intracellular transport of viral material|negative regulation of viral release from host cell|,molecular_function|metal ion binding|,10,0,0,10,0.3,1.2,0.2,0.851,0.851,0.581,0,0,-1.2,1.7
ENSMUSG00000062031,ATHL1,"ATH1, acid trehalase-like 1 (yeast)",cellular_component|,carbohydrate metabolic process|biological_process|metabolic process|,"catalytic activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,-0.3,0.762,10,-0.2,0.226,-0.3,0.848,-0.848,0.582,0,0,-1.5,1.2
ENSMUSG00000055319,SEC23IP,Sec23 interacting protein,endoplasmic reticulum|cis-Golgi network|membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|endoplasmic reticulum exit site|perinuclear endoplasmic reticulum|,acrosome assembly|spermatid development|single fertilization|,poly(A) RNA binding|metal ion binding|,10,0.3,2.63,10,-0.2,0.556,0.2,0.845,0.845,0.582,0,0,-0.9,1.8
ENSMUSG00000002981,CLPTM1,cleft lip and palate associated transmembrane protein 1,external side of plasma membrane|membrane|membrane|integral component of membrane|,multicellular organismal development|cell differentiation|regulation of T cell differentiation in thymus|,molecular_function|,10,0.4,1.44,9,-0.1,0.0157,0.2,0.845,0.845,0.582,0,0,-0.9,1.9
ENSMUSG00000030629,ZFAND6,"zinc finger, AN1-type domain 6",intracellular|cell|cytoplasm|,protein targeting to peroxisome|transport|apoptotic process|signal transduction|protein transport|negative regulation of apoptotic process|regulation of I-kappaB kinase/NF-kappaB signaling|cellular response to tumor necrosis factor|,DNA binding|protein binding|zinc ion binding|polyubiquitin binding|metal ion binding|,10,0.4,2.61,10,-0.1,0.0602,0.3,0.837,0.837,0.584,0,0,-1.2,1.6
ENSMUSG00000017723,WFDC2,WAP four-disulfide core domain 2,extracellular region|extracellular vesicular exosome|,biological_process|negative regulation of peptidase activity|,molecular_function|serine-type endopeptidase inhibitor activity|cysteine-type endopeptidase inhibitor activity|aspartic-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.5,0.459,10,-0.2,0.666,-0.4,0.836,-0.836,0.584,0,0,-1.7,1
ENSMUSG00000000275,TRIM25,tripartite motif-containing 25,nucleus|cytoplasm|cytoplasm|,immune system process|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|innate immune response|regulation of viral entry into host cell|negative regulation of viral entry into host cell|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|defense response to virus|regulation of viral release from host cell|negative regulation of viral release from host cell|,zinc ion binding|ligase activity|poly(A) RNA binding|metal ion binding|,10,-0.4,2.35,10,0,0,-0.2,0.835,-0.835,0.584,0,0,-1.7,0.8
ENSMUSG00000031778,CX3CL1,chemokine (C-X3-C motif) ligand 1,extracellular region|extracellular space|cytoplasm|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|cell projection|perinuclear region of cytoplasm|,chemotaxis|immune response|cell adhesion|positive regulation of macrophage chemotaxis|cytokine-mediated signaling pathway|platelet activation|positive regulation of cell migration|neutrophil chemotaxis|positive regulation of transforming growth factor beta1 production|wound healing|positive regulation of angiogenesis|positive regulation of cell adhesion|negative regulation of vasoconstriction|macrophage chemotaxis|lymphocyte chemotaxis|positive regulation of smooth muscle cell proliferation|negative regulation of cytokine secretion|positive regulation of calcium-independent cell-cell adhesion|angiogenesis involved in wound healing|regulation of inhibitory postsynaptic membrane potential|cell chemotaxis|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,cytokine activity|chemokine activity|chemokine activity|,10,0.1,0.167,10,-0.7,0.948,0.2,0.834,0.834,0.585,0,0,-1.8,1.1
ENSMUSG00000037984,NEUROD6,neurogenic differentiation 6,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|dentate gyrus development|cell differentiation|",DNA binding|protein dimerization activity|,10,-0.2,0.441,10,-0.2,0.46,-0.2,0.827,-0.827,0.586,0,0,-1.7,0.9
ENSMUSG00000020821,KIF1C,kinesin family member 1C,cytoplasm|Golgi apparatus|cytoskeleton|kinesin complex|microtubule|,"retrograde vesicle-mediated transport, Golgi to ER|microtubule-based movement|",nucleotide binding|microtubule motor activity|ATP binding|microtubule binding|poly(A) RNA binding|,10,0.4,2.31,10,0,0,0.3,0.822,0.822,0.587,0,0,-1.1,1.6
ENSMUSG00000039263,NPEPL1,aminopeptidase-like 1,intracellular|nucleus|cytoplasm|,proteolysis|biological_process|protein metabolic process|,aminopeptidase activity|peptidase activity|metalloexopeptidase activity|hydrolase activity|manganese ion binding|metal ion binding|,10,0.2,0.308,10,0.3,0.62,0.3,0.818,0.818,0.588,0,0,-0.5,1.9
ENSMUSG00000001052,SEC24B,"Sec24 related gene family, member B (S. cerevisiae)",COPII vesicle coat|ER to Golgi transport vesicle|,neural tube closure|neural tube closure|auditory receptor cell morphogenesis|auditory receptor cell morphogenesis|outflow tract morphogenesis|transport|protein transport|cochlear nucleus development|cochlear nucleus development|aorta morphogenesis|auditory receptor cell stereocilium organization|auditory receptor cell stereocilium organization|lung morphogenesis|lung lobe morphogenesis|coronary artery morphogenesis|pulmonary artery morphogenesis|cardiovascular system development|regulation of establishment of planar polarity involved in neural tube closure|regulation of cargo loading into COPII-coated vesicle|,protein binding|,10,-0.3,1.68,10,0,0,-0.2,0.814,-0.814,0.589,0,0,-1.6,1
ENSMUSG00000036086,ZRANB3,"zinc finger, RAN-binding domain containing 3",nucleus|chromosome|nuclear replication fork|,"DNA strand renaturation|DNA catabolic process, endonucleolytic|DNA repair|cellular response to DNA damage stimulus|metabolic process|response to UV|replication fork processing|DNA rewinding|negative regulation of DNA recombination|replication fork protection|",nucleotide binding|nucleic acid binding|DNA binding|catalytic activity|helicase activity|nuclease activity|endonuclease activity|endodeoxyribonuclease activity|ATP binding|zinc ion binding|hydrolase activity|annealing helicase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|K63-linked polyubiquitin binding|,10,0,0,10,-0.4,1.51,-0.3,0.806,-0.806,0.591,0,0,-1.7,0.9
ENSMUSG00000006649,NPHS1,"nephrosis 1, nephrin",intracellular|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|slit diaphragm|cell projection|protein complex|membrane raft|extracellular vesicular exosome|,MAPK cascade|cell adhesion|JNK cascade|multicellular organismal development|muscle organ development|skeletal muscle tissue development|myoblast fusion|positive regulation of actin filament polymerization|regulation of excretion|,protein binding|myosin binding|protein domain specific binding|spectrin binding|alpha-actinin binding|,10,0.3,0.599,10,1,0.627,0.2,0.804,0.804,0.591,0,0,-0.6,2
ENSMUSG00000029071,DVL1,"dishevelled, dsh homolog 1 (Drosophila)",cell|cytoplasm|microtubule|microtubule|plasma membrane|cell cortex|microtubule cytoskeleton|microtubule cytoskeleton|membrane|cytoplasmic membrane-bounded vesicle|lateral plasma membrane|clathrin-coated vesicle|axon|axon|dendrite|dendrite|growth cone|growth cone|cytoplasmic vesicle|neuronal cell body|neuronal cell body|synapse|,"regulation of neurotransmitter levels|regulation of protein phosphorylation|negative regulation of protein phosphorylation|transcription from RNA polymerase II promoter|negative regulation of protein kinase activity|neurotransmitter secretion|multicellular organismal development|axonogenesis|axon guidance|neuromuscular junction development|positive regulation of neuron projection development|Wnt signaling pathway|Wnt signaling pathway|Wnt signaling pathway|convergent extension involved in neural plate elongation|positive regulation of Wnt signaling pathway|cytoplasmic microtubule organization|cytoplasmic microtubule organization|negative regulation of protein binding|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|protein localization to nucleus|social behavior|protein localization to microtubule|intracellular signal transduction|receptor clustering|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|collateral sprouting|axon extension|dendrite morphogenesis|synapse organization|synapse organization|convergent extension involved in organogenesis|convergent extension involved in organogenesis|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|prepulse inhibition|skeletal muscle acetylcholine-gated channel clustering|cochlea morphogenesis|planar cell polarity pathway involved in neural tube closure|positive regulation of canonical Wnt signaling pathway|",frizzled binding|frizzled binding|protein binding|enzyme binding|protein kinase binding|protein kinase binding|identical protein binding|Rac GTPase binding|Rac GTPase binding|,10,-0.5,0.669,10,0.4,1.14,-0.5,0.803,-0.803,0.592,0,0,-1.7,1
ENSMUSG00000067081,ASB18,ankyrin repeat and SOCS box-containing 18,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,9,-0.2,0.263,9,0.3,1.14,-0.3,0.803,-0.803,0.592,0,0,-1.6,1.1
ENSMUSG00000031026,TRIM66,tripartite motif-containing 66,intracellular|nucleus|nucleus|chromocenter|aggresome|,"negative regulation of transcription, DNA-templated|",chromatin binding|protein binding|zinc ion binding|protein homodimerization activity|metal ion binding|,10,-0.1,0.0734,10,-0.2,1.02,-0.2,0.8,-0.8,0.592,0,0,-1.7,1.1
ENSMUSG00000022304,DPYS,dihydropyrimidinase,cytoplasm|cytosol|cytosol|extracellular vesicular exosome|,pyrimidine nucleobase catabolic process|thymine catabolic process|thymine catabolic process|uracil catabolic process|uracil catabolic process|beta-alanine metabolic process|beta-alanine metabolic process|uracil metabolic process|protein homooligomerization|protein homooligomerization|protein homotetramerization|protein homotetramerization|,"uracil binding|uracil binding|thymine binding|thymine binding|dihydropyrimidinase activity|dihydropyrimidinase activity|dihydropyrimidinase activity|zinc ion binding|zinc ion binding|amino acid binding|amino acid binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|metal ion binding|phosphoprotein binding|",10,0.3,0.484,10,0.8,1.92,0.3,0.796,0.796,0.593,0,0,-0.7,1.9
ENSMUSG00000020457,DRG1,developmentally regulated GTP binding protein 1,cytoplasm|polysome|membrane|,None,nucleotide binding|GTP binding|identical protein binding|,10,0.2,1.08,10,0.1,0.0052,0.2,0.795,0.795,0.594,0,0,-0.8,1.8
ENSMUSG00000049538,ADAMTS16,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16",cellular_component|extracellular region|proteinaceous extracellular matrix|extracellular matrix|,branching involved in ureteric bud morphogenesis|proteolysis|,molecular_function|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.2,0.501,10,0.8,3.68,0.8,0.792,0.792,0.594,0,0,-0.5,2
ENSMUSG00000024007,PPIL1,peptidylprolyl isomerase (cyclophilin)-like 1,spliceosomal complex|extracellular vesicular exosome|catalytic step 2 spliceosome|,protein peptidyl-prolyl isomerization|mRNA processing|protein folding|RNA splicing|,peptidyl-prolyl cis-trans isomerase activity|isomerase activity|,8,0.8,2.9,9,0,0,0.5,0.787,0.787,0.595,0,0,-0.9,2
ENSMUSG00000005107,SLC2A9,"solute carrier family 2 (facilitated glucose transporter), member 9",nuclear envelope|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|carbohydrate transport|glucose transport|hexose transmembrane transport|urate metabolic process|,glucose transmembrane transporter activity|,10,-0.2,0.592,10,-0.9,0.851,-0.2,0.786,-0.786,0.596,0,0,-2,0.6
ENSMUSG00000027598,ITCH,"itchy, E3 ubiquitin protein ligase",ubiquitin ligase complex|nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|cell cortex|membrane|membrane|cytoplasmic vesicle|,protein polyubiquitination|immune system process|positive regulation of T cell anergy|ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|apoptotic process|protein ubiquitination|protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|protein K29-linked ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|innate immune response|positive regulation of protein catabolic process|positive regulation of protein catabolic process|negative regulation of JNK cascade|negative regulation of alpha-beta T cell proliferation|negative regulation of defense response to virus|negative regulation of defense response to virus|defense response to virus|protein K63-linked ubiquitination|protein K48-linked ubiquitination|protein K48-linked ubiquitination|regulation of protein deubiquitination|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ribonucleoprotein complex binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|CXCR chemokine receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.207,10,0.5,2.01,0.2,0.781,0.781,0.597,0,0,-1.1,1.7
ENSMUSG00000034796,CPNE7,copine VII,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.4,2.03,0.2,0.78,0.78,0.597,0,0,-0.7,1.8
ENSMUSG00000047434,XXYLT1,xyloside xylosyltransferase 1,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.7,2.69,10,-0.1,0.258,-0.1,0.779,-0.779,0.597,0,0,-1.9,0.4
ENSMUSG00000029102,HGFAC,hepatocyte growth factor activator,extracellular region|extracellular space|cytoplasm|rough endoplasmic reticulum|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.4,1.73,10,0.1,0.123,-0.2,0.778,-0.778,0.598,0,0,-1.7,1
ENSMUSG00000030401,RTN2,reticulon 2 (Z-band associated protein),intracellular|cell|endoplasmic reticulum|terminal cisterna|membrane|integral component of membrane|T-tubule|,regulation of glucose import|intracellular protein transmembrane transport|,molecular_function|,10,-0.1,0.686,10,-0.1,0.15,-0.1,0.769,-0.769,0.6,0,0,-0.9,1.9
ENSMUSG00000015575,ATP6V0E,"ATPase, H+ transporting, lysosomal V0 subunit E","membrane|integral component of membrane|proton-transporting V-type ATPase, V0 domain|",transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|cell growth|,hydrogen ion transmembrane transporter activity|hydrolase activity|,10,0.1,0.478,10,0.1,0.36,0.1,0.768,0.768,0.6,0,0,-2,1
ENSMUSG00000027472,PDRG1,p53 and DNA damage regulated 1,cellular_component|cytoplasm|prefoldin complex|,protein folding|biological_process|,molecular_function|unfolded protein binding|,9,0.4,1.44,8,0,0,0.4,0.755,0.755,0.603,0,0,-0.8,2
ENSMUSG00000052392,ACOT4,acyl-CoA thioesterase 4,peroxisome|peroxisome|peroxisome|,very long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|succinyl-CoA metabolic process|succinyl-CoA metabolic process|acyl-CoA metabolic process|acyl-CoA metabolic process|saturated monocarboxylic acid metabolic process|unsaturated monocarboxylic acid metabolic process|dicarboxylic acid metabolic process|dicarboxylic acid metabolic process|dicarboxylic acid catabolic process|short-chain fatty acid metabolic process|short-chain fatty acid metabolic process|,succinyl-CoA hydrolase activity|receptor binding|palmitoyl-CoA hydrolase activity|hydrolase activity|thiolester hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|,10,-0.3,0.899,10,0.1,0.164,-0.3,0.753,-0.753,0.604,0,0,-1.5,1.3
ENSMUSG00000029338,ANTXR2,anthrax toxin receptor 2,membrane|integral component of membrane|,reproductive process|,receptor activity|metal ion binding|,10,0,0,10,-0.7,2.12,-0.4,0.749,-0.749,0.605,0,0,-1.9,0.9
ENSMUSG00000068452,DUOX2,dual oxidase 2,membrane|integral component of membrane|extracellular vesicular exosome|,fertilization|response to virus|cytokine-mediated signaling pathway|bone mineralization|thyroid gland development|multicellular organism growth|thyroid hormone metabolic process|hormone metabolic process|inner ear development|adenohypophysis morphogenesis|response to cAMP|oxidation-reduction process|,calcium ion binding|NAD(P)H oxidase activity|oxidoreductase activity|,10,-0.3,1.12,10,0.1,0.0847,-0.2,0.749,-0.749,0.605,0,0,-1.3,1.4
ENSMUSG00000050079,RSPRY1,ring finger and SPRY domain containing 1,cellular_component|extracellular region|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.2,0.51,10,0.2,0.306,0.2,0.748,0.748,0.605,0,0,-0.8,1.8
ENSMUSG00000019998,STX7,syntaxin 7,lysosomal membrane|endosome|membrane|integral component of membrane|SNARE complex|SNARE complex|late endosome membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|extracellular vesicular exosome|,intracellular protein transport|synaptic vesicle exocytosis|vesicle-mediated transport|,SNARE binding|SNARE binding|SNAP receptor activity|SNAP receptor activity|protein binding|protein complex binding|,9,0,0,9,-0.3,1.44,-0.2,0.744,-0.744,0.606,0,0,-1.7,1.1
ENSMUSG00000045684,LCN6,lipocalin 6,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.1,0.273,10,-0.2,1.32,-0.2,0.741,-0.741,0.607,0,0,-1.3,1.4
ENSMUSG00000020131,PCSK4,proprotein convertase subtilisin/kexin type 4,acrosomal membrane|cell|,proteolysis|binding of sperm to zona pellucida|acrosome reaction|fertilization|sperm capacitation|,serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.761,10,-0.2,0.37,0.1,0.739,0.739,0.607,0,0,-1.4,1.3
ENSMUSG00000042797,AQP11,aquaporin 11,intracellular|cytoplasm|endoplasmic reticulum|cytosol|cell surface|membrane|integral component of membrane|dendrite|,kidney development|transport|water transport|endosomal lumen acidification|protein homooligomerization|transmembrane transport|proximal tubule development|,transporter activity|water channel activity|,10,-0.2,0.549,10,0.2,1.22,0.3,0.734,0.734,0.608,0,0,-0.7,2
ENSMUSG00000042364,SNX18,sorting nexin 18,endosome|plasma membrane|membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic membrane-bounded vesicle|clathrin-coated vesicle|growth cone|extrinsic component of cytoplasmic side of plasma membrane|cytoplasmic vesicle|neuronal cell body|extracellular vesicular exosome|,mitotic cytokinesis|transport|intracellular protein transport|endocytosis|cell cycle|mitotic nuclear division|protein transport|endosomal transport|cleavage furrow formation|positive regulation of GTPase activity|cell division|,"protein binding|phosphatidylinositol-4,5-bisphosphate binding|lipid binding|phosphatidylinositol binding|",9,-0.5,1.74,9,0,0,0.3,0.731,0.731,0.609,0,0,-1.5,1.5
ENSMUSG00000006948,KLK4,"kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)",cellular_component|,proteolysis|extracellular matrix disassembly|protein catabolic process|amelogenesis|amelogenesis|,molecular_function|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.3,1.35,0.2,0.73,0.73,0.609,0,0,-0.9,1.8
ENSMUSG00000056091,ST3GAL5,"ST3 beta-galactoside alpha-2,3-sialyltransferase 5",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|sialylation|,"sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|lactosylceramide alpha-2,3-sialyltransferase activity|",10,0.1,0.34,10,0.2,0.554,0.2,0.722,0.722,0.611,0,0,-1.3,1.5
ENSMUSG00000010051,HYAL1,hyaluronoglucosaminidase 1,extracellular region|extracellular space|cytoplasm|lysosome|cytoplasmic vesicle|hyaluranon cable|extracellular vesicular exosome|,response to reactive oxygen species|carbohydrate metabolic process|inflammatory response|metabolic process|cell death|negative regulation of cell proliferation|response to virus|response to virus|positive regulation of epithelial cell migration|hyaluronan metabolic process|hyaluronan biosynthetic process|hyaluronan catabolic process|positive regulation of cell growth|negative regulation of cell growth|cellular response to platelet-derived growth factor stimulus|cellular response to fibroblast growth factor stimulus|positive regulation of angiogenesis|positive regulation of cell adhesion|positive regulation of growth|response to antibiotic|positive regulation of epithelial cell proliferation|embryonic skeletal joint morphogenesis|cellular response to interleukin-1|cellular response to pH|cellular response to UV-B|positive regulation of hyaluranon cable assembly|,"catalytic activity|hyalurononglucosaminidase activity|transcription factor binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|hyaluronan synthase activity|",10,0.3,0.7,10,0.1,0.137,0.3,0.722,0.722,0.611,0,0,-0.6,1.9
ENSMUSG00000035692,ISG15,ISG15 ubiquitin-like modifier,extracellular region|cytoplasm|,modification-dependent protein catabolic process|negative regulation of protein ubiquitination|ISG15-protein conjugation|ISG15-protein conjugation|regulation of interferon-gamma production|response to type I interferon|defense response to bacterium|defense response to bacterium|negative regulation of viral genome replication|positive regulation of erythrocyte differentiation|defense response to virus|defense response to virus|,protein binding|protein tag|,10,0.2,0.88,10,0.1,0.0112,0.2,0.716,0.716,0.613,0,0,-0.8,1.8
ENSMUSG00000034109,GOLIM4,golgi integral membrane protein 4,nucleus|endosome|Golgi apparatus|membrane|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,-0.2,1.11,10,0.1,0.223,-0.2,0.712,-0.712,0.614,0,0,-1.4,1.4
ENSMUSG00000050463,KRT78,keratin 78,extracellular space|intermediate filament|extracellular vesicular exosome|,biological_process|,molecular_function|,9,0.1,0.0229,9,0.9,1.03,0.2,0.71,0.71,0.614,0,0,-0.9,2
ENSMUSG00000047638,NR1H4,"nuclear receptor subfamily 1, group H, member 4",nucleus|nuclear euchromatin|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nitrogen catabolite activation of transcription from RNA polymerase II promoter|regulation of carbohydrate metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|bile acid metabolic process|bile acid metabolic process|intracellular receptor signaling pathway|regulation of urea metabolic process|intracellular bile acid receptor signaling pathway|steroid hormone mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of bile acid biosynthetic process|cellular response to acid|cellular response to acid|cellular response to organonitrogen compound|positive regulation of glutamate metabolic process|positive regulation of ammonia assimilation cycle|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|thyroid hormone receptor activity|zinc ion binding|bile acid binding|bile acid binding|bile acid receptor activity|peptide binding|sequence-specific DNA binding|metal ion binding|retinoid X receptor binding|chenodeoxycholic acid binding|,10,0.2,0.619,10,-0.3,1.03,-0.2,0.708,-0.708,0.615,0,0,-1.3,1.5
ENSMUSG00000036138,ACAA1A,acetyl-Coenzyme A acyltransferase 1A,mitochondrion|peroxisome|peroxisome|peroxisome|membrane|intracellular membrane-bounded organelle|,very long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|metabolic process|bile acid metabolic process|,"catalytic activity|acetyl-CoA C-acetyltransferase activity|acetyl-CoA C-acyltransferase activity|palmitoyl-CoA oxidase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|",10,0.2,1.19,10,0,0,0.2,0.708,0.708,0.615,0,0,-0.9,1.8
ENSMUSG00000032181,SCG3,secretogranin III,extracellular region|membrane|cytoplasmic vesicle|,None,poly(A) RNA binding|,10,0.2,0.473,10,-0.2,0.691,-0.1,0.707,-0.707,0.615,0,0,-1.1,1.7
ENSMUSG00000038014,FAM120A,"family with sequence similarity 120, member A",cytoplasm|plasma membrane|membrane|membrane|,None,RNA binding|poly(A) RNA binding|,10,0.1,0.0838,10,0.2,0.766,0.2,0.706,0.706,0.615,0,0,-1.5,1.4
ENSMUSG00000025952,CRYGC,"crystallin, gamma C",nucleus|cytoplasm|,eye development|visual perception|camera-type eye development|,structural constituent of eye lens|,6,-0.3,0.258,6,0.4,0.908,0.4,0.705,0.705,0.616,0,0,-1.2,2
ENSMUSG00000039070,CPA4,carboxypeptidase A4,cellular_component|extracellular region|,proteolysis|,molecular_function|carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,9,0.1,0.0377,9,-0.5,1.45,-0.5,0.702,-0.702,0.616,0,0,-1.9,0.8
ENSMUSG00000054517,TRIM65,tripartite motif-containing 65,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.5,1.9,10,0,0,0.4,0.7,0.7,0.617,0,0,-0.5,2
ENSMUSG00000069633,PEX11G,peroxisomal biogenesis factor 11 gamma,peroxisome|integral component of peroxisomal membrane|membrane|integral component of membrane|intrinsic component of peroxisomal membrane|protein complex|,peroxisome fission|regulation of peroxisome size|,molecular_function|,10,-0.6,1.09,10,0.5,2.56,0.4,0.698,0.698,0.617,0,0,-1.3,1.6
ENSMUSG00000040697,DNAJC16,"DnaJ (Hsp40) homolog, subfamily C, member 16",cellular_component|membrane|integral component of membrane|,biological_process|cell redox homeostasis|,None,10,0.3,1.56,10,0,0,0.2,0.694,0.694,0.618,0,0,-0.9,1.7
ENSMUSG00000000318,CLEC10A,"C-type lectin domain family 10, member A",membrane|integral component of membrane|,None,carbohydrate binding|,10,0.5,1.63,10,-0.1,0.254,0.3,0.693,0.693,0.619,0,0,-1,1.6
ENSMUSG00000059555,TOR4A,"torsin family 4, member A",cellular_component|membrane|integral component of membrane|,biological_process|chaperone mediated protein folding requiring cofactor|,nucleotide binding|ATP binding|,10,0.3,0.137,10,1.2,2.09,1.1,0.69,0.69,0.62,0,0,-0.3,2
ENSMUSG00000032565,NUDT16,nudix (nucleoside diphosphate linked moiety X)-type motif 16,nucleus|nucleolus|cytoplasm|,adenosine to inosine editing|mRNA catabolic process|mRNA catabolic process|proteolysis|positive regulation of cell proliferation|nucleotide metabolic process|snoRNA catabolic process|dephosphorylation|dephosphorylation|dITP catabolic process|IDP catabolic process|chromosome organization|positive regulation of cell cycle process|XDP catabolic process|positive regulation of double-strand break repair|,"nucleotide binding|magnesium ion binding|RNA binding|mRNA binding|thiamine-pyrophosphatase activity|GTP binding|metalloexopeptidase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|manganese ion binding|snoRNA binding|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|protein homodimerization activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|m7G(5')pppN diphosphatase activity|cobalt ion binding|inosine-diphosphatase activity|dIDP diphosphatase activity|nucleotide phosphatase activity, acting on free nucleotides|nucleotide phosphatase activity, acting on free nucleotides|XTP binding|ITP binding|",10,0.3,1.93,10,0,0,0.3,0.687,0.687,0.62,0,0,-1.6,1.3
ENSMUSG00000040327,CUL9,cullin 9,cytoplasm|cullin-RING ubiquitin ligase complex|cullin-RING ubiquitin ligase complex|,microtubule cytoskeleton organization|ubiquitin-dependent protein catabolic process|regulation of mitosis|protein ubiquitination|,nucleotide binding|ATP binding|zinc ion binding|ubiquitin protein ligase binding|metal ion binding|,10,-1.1,1.5,10,-0.2,0.311,-0.3,0.682,-0.682,0.621,0,0,-2,0.7
ENSMUSG00000004768,RAB23,"RAB23, member RAS oncogene family",cytoplasm|endosome|autophagic vacuole|plasma membrane|endosome membrane|membrane|cytoplasmic vesicle|phagocytic vesicle|extracellular vesicular exosome|,autophagic vacuole assembly|neural tube closure|GTP catabolic process|transport|cellular defense response|signal transduction|small GTPase mediated signal transduction|multicellular organismal development|nervous system development|regulation of smoothened signaling pathway|protein transport|spinal cord dorsal/ventral patterning|spinal cord dorsal/ventral patterning|dorsal/ventral neural tube patterning|embryonic digit morphogenesis|negative regulation of transcription factor import into nucleus|negative regulation of proteolysis|craniofacial suture morphogenesis|,nucleotide binding|GTPase activity|GTP binding|,10,0.2,0.981,10,-0.2,0.366,0.2,0.675,0.675,0.623,0,0,-1.2,1.5
ENSMUSG00000079108,SRP54B,signal recognition particle 54B,"nucleus|signal recognition particle, endoplasmic reticulum targeting|",biological_process|,GTPase activity|GTP binding|drug binding|GDP binding|endoplasmic reticulum signal peptide binding|poly(A) RNA binding|,2,-0.2,0.336,2,-0.2,0.4,-0.2,0.674,-0.674,0.623,0,0,-2,1.6
ENSMUSG00000070719,PLA2G4D,"phospholipase A2, group IVD",cytoplasm|membrane|cytoplasmic vesicle|,lipid metabolic process|metabolic process|phospholipid catabolic process|lipid catabolic process|,phospholipase activity|phospholipase A2 activity|hydrolase activity|metal ion binding|,10,0.2,0.621,10,-0.4,0.623,0.2,0.668,0.668,0.625,0,0,-1.5,1.3
ENSMUSG00000017493,IGFBP4,insulin-like growth factor binding protein 4,extracellular region|extracellular space|,regulation of cell growth|regulation of glucose metabolic process|regulation of growth|positive regulation of MAPK cascade|positive regulation of insulin-like growth factor receptor signaling pathway|type B pancreatic cell proliferation|,insulin-like growth factor binding|growth factor binding|,10,0.5,2.06,10,-1.1,1.69,-0.1,0.668,-0.668,0.625,0,0,-2,1.3
ENSMUSG00000094040,TNFAIP8,"tumor necrosis factor, alpha-induced protein 8",cytoplasm|,apoptotic process|interleukin-1 beta production|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|defense response to Gram-positive bacterium|,cysteine-type endopeptidase inhibitor activity involved in apoptotic process|,10,0.4,2.62,10,-0.1,0.041,0.3,0.668,0.668,0.625,0,0,-1.5,1.3
ENSMUSG00000043885,SLC36A4,"solute carrier family 36 (proton/amino acid symporter), member 4",cellular_component|membrane|integral component of membrane|,transport|amino acid transport|L-alanine transport|proline transport|tryptophan transport|,molecular_function|symporter activity|,10,0.1,0.0309,10,-0.2,0.833,-0.2,0.661,-0.661,0.627,0,0,-1.1,1.8
ENSMUSG00000037548,H2-DMB2,"histocompatibility 2, class II, locus Mb2",lysosome|lysosomal membrane|late endosome|multivesicular body|endosome membrane|membrane|integral component of membrane|MHC class II protein complex|,immune system process|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|antigen processing and presentation|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|chaperone mediated protein folding requiring cofactor|,protein binding|MHC class II protein complex binding|,10,0.1,0.524,10,0.1,0.195,0.1,0.659,0.659,0.627,0,0,-0.6,2
ENSMUSG00000038007,ACER2,alkaline ceramidase 2,Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,negative regulation of cell-matrix adhesion|lipid metabolic process|ceramide metabolic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of cell proliferation|positive regulation of cell death|response to retinoic acid|negative regulation of cell adhesion mediated by integrin|sphingosine biosynthetic process|negative regulation of protein glycosylation in Golgi|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|ceramidase activity|dihydroceramidase activity|",10,0.1,0.0704,10,0.8,0.875,0.3,0.658,0.658,0.627,0,0,-0.4,2
ENSMUSG00000020889,NR1D1,"nuclear receptor subfamily 1, group D, member 1",nuclear chromatin|nucleus|cytoplasm|dendrite|cell projection|dendritic spine|,"negative regulation of transcription from RNA polymerase II promoter|glycogen biosynthetic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|circadian rhythm|proteasomal protein catabolic process|negative regulation of receptor biosynthetic process|regulation of lipid metabolic process|cell differentiation|circadian regulation of gene expression|negative regulation of toll-like receptor 4 signaling pathway|regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter|regulation of circadian rhythm|regulation of circadian rhythm|steroid hormone mediated signaling pathway|response to leptin|regulation of fat cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|rhythmic process|circadian temperature homeostasis|regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of type B pancreatic cell proliferation|positive regulation of bile acid biosynthetic process|cellular response to lipopolysaccharide|regulation of cholesterol homeostasis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|core promoter sequence-specific DNA binding|core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|transcription corepressor binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|protein binding|zinc ion binding|heme binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0.1,0.0559,10,-0.4,2.19,-0.2,0.656,-0.656,0.628,0,0,-1.8,1
ENSMUSG00000039911,SPSB1,splA/ryanodine receptor domain and SOCS box containing 1,cytoplasm|,intracellular signal transduction|,None,10,0.5,2.48,10,0,0,0.4,0.651,0.651,0.629,0,0,-0.4,2
ENSMUSG00000001473,TUBB6,"tubulin, beta 6 class V",nucleus|cytoplasm|cytoskeleton|microtubule|protein complex|extracellular vesicular exosome|,GTP catabolic process|microtubule-based process|protein polymerization|,nucleotide binding|GTPase activity|structural constituent of cytoskeleton|GTP binding|,10,0.3,0.983,10,-0.4,2.04,-0.3,0.651,-0.651,0.629,0,0,-1.8,1
ENSMUSG00000024725,OSTF1,osteoclast stimulating factor 1,cytoplasm|extracellular vesicular exosome|,biological_process|,SH3 domain binding|,10,0.3,1.38,10,0,0,0.2,0.651,0.651,0.629,0,0,-0.7,2
ENSMUSG00000001510,DLX3,distal-less homeobox 3,nucleus|,"blood vessel development|placenta development|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|odontogenesis of dentin-containing tooth|positive regulation of transcription from RNA polymerase II promoter|odontoblast differentiation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding|,10,1,1.64,10,0,0,0.6,0.649,0.649,0.629,0,0,-0.5,2
ENSMUSG00000027708,DCUN1D1,"DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)",ubiquitin ligase complex|,None,None,10,-0.2,1.41,10,0,0,-0.2,0.644,-0.644,0.631,0,0,-1.5,1.3
ENSMUSG00000024580,GRPEL2,"GrpE-like 2, mitochondrial",mitochondrion|mitochondrial inner membrane|,protein folding|,adenyl-nucleotide exchange factor activity|protein homodimerization activity|unfolded protein binding|chaperone binding|,10,-0.3,0.312,10,0.3,0.631,0.2,0.642,0.642,0.631,0,0,-1.3,1.5
ENSMUSG00000057706,MEX3B,mex3 homolog B (C. elegans),nucleus|cytoplasm|,biological_process|,RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,0.3,0.96,0.2,0.64,0.64,0.632,0,0,-0.6,2
ENSMUSG00000074336,APOC4,apolipoprotein C-IV,extracellular region|very-low-density lipoprotein particle|very-low-density lipoprotein particle|high-density lipoprotein particle|,transport|lipid transport|positive regulation of sequestering of triglyceride|triglyceride homeostasis|,None,10,0.1,0.174,10,0.2,0.631,0.2,0.632,0.632,0.634,0,0,-0.9,1.8
ENSMUSG00000023433,CELA3B,"chymotrypsin-like elastase family, member 3B",cellular_component|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,0.796,10,0.4,0.704,-0.2,0.628,-0.628,0.635,0,0,-1.4,1.4
ENSMUSG00000058761,RNF169,ring finger protein 169,nucleus|nucleoplasm|plasma membrane|site of double-strand break|intracellular membrane-bounded organelle|,cellular response to DNA damage stimulus|negative regulation of double-strand break repair|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|nucleosome binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|K63-linked polyubiquitin binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,1.17,10,0,0,-0.2,0.626,-0.626,0.635,0,0,-1.3,1.6
ENSMUSG00000034928,RNF44,ring finger protein 44,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.3,0.831,10,-0.1,0.101,-0.3,0.622,-0.622,0.637,0,0,-1.8,0.9
ENSMUSG00000021866,ANXA11,annexin A11,nucleus|nuclear envelope|nucleoplasm|cytoplasm|cytoplasm|spindle|cytoskeleton|membrane|midbody|specific granule|azurophil granule|phagocytic vesicle|extracellular vesicular exosome|,"cell cycle|cytokinesis, completion of separation|cell division|response to calcium ion|",calcium ion binding|calcium-dependent phospholipid binding|phosphatidylethanolamine binding|MHC class II protein complex binding|S100 protein binding|poly(A) RNA binding|calcium-dependent protein binding|,10,0,0,10,-0.8,2.13,0.2,0.62,0.62,0.637,0,0,-1.8,1.2
ENSMUSG00000024317,RNF138,ring finger protein 138,nucleus|,biological_process|Wnt signaling pathway|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein kinase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,1.36,10,0,0,-0.2,0.618,-0.618,0.638,0,0,-1.5,1.2
ENSMUSG00000025409,MBD6,methyl-CpG binding domain protein 6,nucleus|chromosome|chromocenter|,biological_process|,DNA binding|chromatin binding|,10,-0.2,0.163,10,-0.2,0.506,-0.2,0.614,-0.614,0.639,0,0,-1.7,1
ENSMUSG00000046269,USP27X,"ubiquitin specific peptidase 27, X chromosome",cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|metal ion binding|,10,0.4,1.15,10,0,0,0.2,0.613,0.613,0.639,0,0,-1.1,1.6
ENSMUSG00000039501,ZNFX1,"zinc finger, NFX1-type containing 1",cellular_component|,biological_process|,poly(A) RNA binding|metal ion binding|,10,-0.2,0.471,10,-0.1,0.22,-0.1,0.611,-0.611,0.64,0,0,-1.7,1
ENSMUSG00000040359,UFL1,UFM1 specific ligase 1,nucleus|cytoplasm|endoplasmic reticulum|membrane|,osteoblast differentiation|negative regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|regulation of proteasomal ubiquitin-dependent protein catabolic process|response to endoplasmic reticulum stress|protein ufmylation|,"UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|UFM1 conjugating enzyme activity|",10,-0.2,0.827,10,0.2,0.611,0.2,0.608,0.608,0.64,0,0,-0.7,2
ENSMUSG00000025340,RABGEF1,RAB guanine nucleotide exchange factor (GEF) 1,cytoplasm|endosome|vesicle|,negative regulation of protein phosphorylation|negative regulation of leukocyte migration|transport|endocytosis|protein transport|protein ubiquitination|positive regulation of Rab GTPase activity|negative regulation of mast cell activation|negative regulation of mast cell degranulation|negative regulation of Ras protein signal transduction|negative regulation of receptor-mediated endocytosis|negative regulation of inflammatory response|regulation of Fc receptor mediated stimulatory signaling pathway|regulation of Fc receptor mediated stimulatory signaling pathway|negative regulation of interleukin-6 secretion|negative regulation of Kit signaling pathway|,DNA binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|Rab guanyl-nucleotide exchange factor activity|metal ion binding|,10,0.2,0.289,10,0.3,0.387,0.2,0.602,0.602,0.642,0,0,-1.2,1.5
ENSMUSG00000020079,SUPV3L1,"suppressor of var1, 3-like 1 (S. cerevisiae)",nucleus|mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial nucleoid|mitochondrial degradosome|,mitochondrial mRNA catabolic process|positive regulation of mitochondrial RNA catabolic process|mitochondrial RNA 3'-end processing|ATP catabolic process|DNA recombination|RNA catabolic process|positive regulation of cell growth|DNA duplex unwinding|mitochondrial ncRNA surveillance|mitochondrial mRNA surveillance|negative regulation of apoptotic process|mitochondrion morphogenesis|chromatin maintenance|mitochondrial RNA surveillance|,"nucleotide binding|DNA binding|DNA helicase activity|double-stranded RNA binding|ATP-dependent RNA helicase activity|helicase activity|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|3'-5' RNA helicase activity|protein homodimerization activity|poly(A) RNA binding|",7,-0.8,0.25,5,-0.2,0.651,-0.2,0.6,-0.6,0.643,0,0,-2,1.1
ENSMUSG00000044626,LIPH,"lipase, member H",extracellular region|extracellular space|plasma membrane|membrane|,lipid metabolic process|lipid catabolic process|,"catalytic activity|phospholipase activity|heparin binding|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,1.3,1.87,10,-0.3,1.33,-0.2,0.597,-0.597,0.643,0,0,-1,2
ENSMUSG00000021903,GALNT15,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15,Golgi apparatus|membrane|integral component of membrane|transport vesicle|,biological_process|,"molecular_function|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0.3,0.662,10,-1.1,1.8,0.2,0.596,0.596,0.644,0,0,-2,1.1
ENSMUSG00000068329,HTRA2,HtrA serine peptidase 2,chromatin|intracellular|nucleus|mitochondrion|mitochondrion|mitochondrial intermembrane space|cytosol|cytoskeleton|cytoplasmic side of plasma membrane|membrane|membrane|integral component of membrane|CD40 receptor complex|,proteolysis|apoptotic process|mitochondrion organization|adult walking behavior|adult locomotory behavior|intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of cell death|forebrain development|cellular response to heat|regulation of multicellular organism growth|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|neuron development|negative regulation of cell death|cellular response to growth factor stimulus|intrinsic apoptotic signaling pathway|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|,catalytic activity|serine-type endopeptidase activity|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.3,1.11,-0.2,0.594,-0.594,0.644,0,0,-1,2
ENSMUSG00000027500,STMN2,stathmin-like 2,cytoplasm|endosome|Golgi apparatus|membrane|lamellipodium|growth cone|growth cone|vesicle|cell projection|neuron projection|neuronal cell body|perinuclear region of cytoplasm|,negative regulation of microtubule depolymerization|positive regulation of neuron projection development|negative regulation of neuron projection development|regulation of microtubule polymerization or depolymerization|negative regulation of microtubule polymerization|positive regulation of microtubule depolymerization|cellular response to nerve growth factor stimulus|,protein binding|calcium-dependent protein binding|,10,-0.5,1.23,10,-0.1,0.136,-0.2,0.591,-0.591,0.645,0,0,-1.9,0.7
ENSMUSG00000031078,CTTN,cortactin,ruffle|cytoplasm|cytoplasm|cytoskeleton|cell cortex|lamellipodium|lamellipodium|cell projection|extracellular vesicular exosome|mitotic spindle midzone|,receptor-mediated endocytosis|negative regulation of extrinsic apoptotic signaling pathway|,protein binding|proline-rich region binding|,10,0.2,0.982,10,0,0,0.1,0.585,0.585,0.647,0,0,-1.3,1.5
ENSMUSG00000050799,HIST1H2BA,"histone cluster 1, H2ba",nucleosome|nucleus|chromosome|extrinsic component of plasma membrane|,"nucleosome assembly|nucleosome disassembly|inflammatory response|plasminogen activation|spermatogenesis, exchange of chromosomal proteins|positive regulation of binding|cellular response to acid|mononuclear cell migration|",DNA binding|protein heterodimerization activity|,9,-0.5,0.842,9,0,0,-0.6,0.584,-0.584,0.647,0,0,-2,1
ENSMUSG00000028776,TINAGL1,tubulointerstitial nephritis antigen-like 1,extracellular region|cytoplasm|extracellular matrix|extracellular vesicular exosome|,proteolysis|immune response|,scavenger receptor activity|cysteine-type peptidase activity|polysaccharide binding|laminin binding|,9,0.3,0.778,9,0.1,0.0846,0.2,0.581,0.581,0.648,0,0,-0.8,1.9
ENSMUSG00000029863,CASP2,caspase 2,intracellular|nucleus|cytoplasm|mitochondrion|membrane|,"proteolysis|proteolysis|apoptotic process|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|intrinsic apoptotic signaling pathway in response to DNA damage|protein processing|ectopic germ cell programmed cell death|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of neuron apoptotic process|apoptotic signaling pathway|extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of apoptotic signaling pathway|",cysteine-type endopeptidase activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|protein domain specific binding|cysteine-type endopeptidase activity involved in apoptotic process|,9,0.1,0.0601,9,0.2,0.633,0.1,0.58,0.58,0.649,0,0,-1.1,1.8
ENSMUSG00000042210,ABHD14A,abhydrolase domain containing 14A,cytoplasm|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0.6,1.77,10,-0.1,0.0804,0.2,0.579,0.579,0.649,0,0,-1,1.8
ENSMUSG00000078652,PSME3,"proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)",proteasome complex|nucleus|cytoplasm|proteasome activator complex|membrane|,proteolysis|apoptotic process|cell cycle|positive regulation of endopeptidase activity|regulation of proteasomal protein catabolic process|negative regulation of extrinsic apoptotic signaling pathway|,p53 binding|peptidase activity|hydrolase activity|endopeptidase activator activity|MDM2/MDM4 family protein binding|,10,0,0,10,0.3,1.13,0.2,0.579,0.579,0.649,0,0,-1.1,1.6
ENSMUSG00000023122,SULT1C2,"sulfotransferase family, cytosolic, 1C, member 2",lysosome|extracellular vesicular exosome|,sulfation|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,-0.2,0.838,10,0.6,0.327,-0.2,0.576,-0.576,0.65,0,0,-1.3,1.7
ENSMUSG00000040284,GZMG,granzyme G,membrane|,cytolysis|,catalytic activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.5,1.79,0.4,0.572,0.572,0.651,0,0,-0.6,1.9
ENSMUSG00000049148,PLCXD3,"phosphatidylinositol-specific phospholipase C, X domain containing 3",cellular_component|,lipid metabolic process|signal transduction|lipid catabolic process|,molecular_function|signal transducer activity|phosphoric diester hydrolase activity|hydrolase activity|,10,0.5,0.648,10,0.2,0.072,0.2,0.572,0.572,0.651,0,0,-0.6,1.9
ENSMUSG00000033400,AGL,"amylo-1,6-glucosidase, 4-alpha-glucanotransferase",nucleus|nucleus|cytoplasm|cytoplasm|inclusion body|sarcoplasmic reticulum|,glycogen metabolic process|glycogen catabolic process|glycogen catabolic process|response to nutrient|response to hormone|response to glucocorticoid|,"glycogen debranching enzyme activity|4-alpha-glucanotransferase activity|4-alpha-glucanotransferase activity|amylo-alpha-1,6-glucosidase activity|amylo-alpha-1,6-glucosidase activity|protein binding|carbohydrate binding|polysaccharide binding|polysaccharide binding|polyubiquitin binding|polyubiquitin binding|",10,-0.1,0.234,9,-0.2,0.649,-0.2,0.566,-0.566,0.652,0,0,-1.6,1.3
ENSMUSG00000034738,NOSTRIN,nitric oxide synthase trafficker,nucleus|cytoplasm|plasma membrane|membrane|cytoplasmic vesicle|,"endocytosis|negative regulation of transcription, DNA-templated|regulation of nitric-oxide synthase activity|",DNA binding|protein binding|,10,-0.4,0.714,10,-0.1,0.00261,-0.1,0.561,-0.561,0.654,0,0,-1.9,0.8
ENSMUSG00000025427,RNF165,ring finger protein 165,nucleus|protein complex|,protein polyubiquitination|axonogenesis|motor neuron axon guidance|multicellular organismal aging|protein catabolic process|positive regulation of BMP signaling pathway|forelimb morphogenesis|limb development|innervation|muscle structure development|,ubiquitin-protein transferase activity|protein binding|,10,-0.1,0.0187,10,-0.2,0.978,-0.1,0.552,-0.552,0.656,0,0,-1.6,1.2
ENSMUSG00000012187,MOGAT1,monoacylglycerol O-acyltransferase 1,endoplasmic reticulum|membrane|integral component of membrane|,glycerol metabolic process|lipid metabolic process|diacylglycerol biosynthetic process|,"2-acylglycerol O-acyltransferase activity|diacylglycerol O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|",10,-0.2,0.715,10,0.9,3.05,0.8,0.547,0.547,0.658,0,0,-0.6,2
ENSMUSG00000032207,LIPC,"lipase, hepatic",extracellular region|extracellular space|extracellular space|early endosome|late endosome|microvillus|cell surface|high-density lipoprotein particle|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|triglyceride metabolic process|phosphatidylserine metabolic process|cholesterol metabolic process|heparan sulfate proteoglycan biosynthetic process|lipid catabolic process|triglyceride catabolic process|cholesterol transport|chylomicron remodeling|very-low-density lipoprotein particle remodeling|low-density lipoprotein particle remodeling|high-density lipoprotein particle remodeling|chylomicron remnant clearance|low-density lipoprotein particle clearance|cholesterol homeostasis|cholesterol homeostasis|phosphatidylethanolamine metabolic process|neutral lipid catabolic process|phosphatidylcholine metabolic process|phosphatidic acid metabolic process|glycerophospholipid catabolic process|protein oligomerization|triglyceride homeostasis|regulation of plasma lipoprotein particle levels|,"catalytic activity|lysophospholipase activity|triglyceride lipase activity|protein binding|heparin binding|lipid binding|phosphatidylcholine 1-acylhydrolase activity|lipase activity|transferase activity, transferring acyl groups|hydrolase activity|low-density lipoprotein particle binding|apolipoprotein binding|chylomicron binding|heparan sulfate proteoglycan binding|acylglycerol lipase activity|carboxylic ester hydrolase activity|",10,0.2,0.64,10,-0.2,0.74,-0.2,0.545,-0.545,0.658,0,0,-1.4,1.5
ENSMUSG00000052299,LTN1,listerin E3 ubiquitin protein ligase 1,cellular_component|,cell death|protein autoubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.4,0.887,10,0.1,0.072,0.4,0.543,0.543,0.659,0,0,-0.3,2
ENSMUSG00000016024,LBP,lipopolysaccharide binding protein,extracellular region|extracellular space|extracellular space|cell surface|cell surface|extracellular vesicular exosome|,leukocyte chemotaxis involved in inflammatory response|macrophage activation involved in immune response|immune system process|transport|lipid transport|acute-phase response|lipopolysaccharide transport|lipopolysaccharide-mediated signaling pathway|detection of molecule of bacterial origin|response to lipopolysaccharide|response to lipopolysaccharide|negative regulation of tumor necrosis factor production|positive regulation of chemokine production|positive regulation of interleukin-6 production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of toll-like receptor 4 signaling pathway|positive regulation of tumor necrosis factor biosynthetic process|defense response to bacterium|positive regulation of macrophage activation|negative regulation of growth of symbiont in host|innate immune response|defense response to Gram-negative bacterium|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|positive regulation of respiratory burst involved in inflammatory response|cellular response to lipopolysaccharide|cellular response to lipoteichoic acid|positive regulation of neutrophil chemotaxis|,lipopolysaccharide binding|lipopolysaccharide binding|receptor binding|lipid binding|lipoteichoic acid binding|,10,0.4,0.289,10,0.2,0.422,0.2,0.543,0.543,0.659,0,0,-1,1.7
ENSMUSG00000027907,S100A11,S100 calcium binding protein A11 (calgizzarin),nucleus|cytoplasm|,regulation of cell proliferation|,calcium ion binding|metal ion binding|calcium-dependent protein binding|,10,0,0,10,1.2,2.5,-0.2,0.541,-0.541,0.659,0,0,-0.8,2
ENSMUSG00000034701,NEUROD1,neurogenic differentiation 1,intracellular|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|,"pancreatic A cell fate commitment|pancreatic PP cell fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|nucleocytoplasmic transport|nitric oxide mediated signal transduction|multicellular organismal development|nervous system development|response to glucose|anterior/posterior pattern specification|dentate gyrus development|dentate gyrus development|cerebellum development|signal transduction involved in regulation of gene expression|insulin secretion|cell differentiation|hindbrain development|endocrine pancreas development|amacrine cell differentiation|enteroendocrine cell differentiation|glucose homeostasis|camera-type eye development|positive regulation of apoptotic process|cell fate commitment|positive regulation of cell differentiation|regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of JAK-STAT cascade|embryonic organ morphogenesis|inner ear development|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|regulation of intestinal epithelial structure maintenance|regulation of cell cycle arrest|cellular response to glucose stimulus|negative regulation of type B pancreatic cell apoptotic process|positive regulation of transcription regulatory region DNA binding|",RNA polymerase II activating transcription factor binding|RNA polymerase II transcription coactivator activity|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|E-box binding|E-box binding|,10,0.1,0.131,10,0.2,0.65,0.2,0.54,0.54,0.66,0,0,-1.3,1.6
ENSMUSG00000016481,CR1L,complement component (3b/4b) receptor 1-like,external side of plasma membrane|membrane|integral component of membrane|receptor complex|,"in utero embryonic development|immune system process|complement activation, classical pathway|multicellular organismal development|female pregnancy|regulation of complement activation|regulation of complement activation|innate immune response|negative regulation of complement activation|negative regulation of complement activation|",None,9,-1,1.26,8,0,0,-0.1,0.538,-0.538,0.66,0,0,-2,0.8
ENSMUSG00000024160,SPSB3,splA/ryanodine receptor domain and SOCS box containing 3,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0.1,0.0592,10,0.2,0.668,0.1,0.537,0.537,0.661,0,0,-1,1.7
ENSMUSG00000002104,RAPSN,receptor-associated protein of the synapse,cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|membrane|cell junction|neuromuscular junction|neuromuscular junction|synapse|postsynaptic membrane|,"synaptic transmission|synaptic transmission, cholinergic|positive regulation of neuron apoptotic process|skeletal muscle acetylcholine-gated channel clustering|positive regulation of neuromuscular synaptic transmission|regulation of postsynaptic membrane organization|",zinc ion binding|acetylcholine receptor binding|acetylcholine receptor binding|ionotropic glutamate receptor binding|protein anchor|metal ion binding|,10,0,0,10,-0.3,1.23,-0.2,0.532,-0.532,0.662,0,0,-1.6,1.1
ENSMUSG00000012848,RPS5,ribosomal protein S5,ribosome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|regulation of translational fidelity|,RNA binding|mRNA binding|structural constituent of ribosome|poly(A) RNA binding|,4,0.2,0.6,3,-0.2,0.172,0.2,0.525,0.525,0.664,0,0,-1.6,1.9
ENSMUSG00000057719,SH3RF2,SH3 domain containing ring finger 2,cellular_component|,negative regulation of phosphatase activity|,"protein phosphatase inhibitor activity|protein phosphatase 1 binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|phosphatase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,0.718,9,1,0.699,0.3,0.521,0.521,0.665,0,0,-0.6,2
ENSMUSG00000022184,FBXO4,F-box protein 4,ubiquitin ligase complex|cytoplasm|SCF ubiquitin ligase complex|,protein polyubiquitination|telomere maintenance|ubiquitin-dependent protein catabolic process|protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination|,ubiquitin-protein transferase activity|protein binding|protein homodimerization activity|,10,0.2,0.945,10,0,0,0.1,0.517,0.517,0.666,0,0,-0.9,1.8
ENSMUSG00000042293,GM5617,predicted gene 5617,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0767,10,-0.2,0.761,-0.1,0.516,-0.516,0.667,0,0,-1.6,1.2
ENSMUSG00000026100,MSTN,myostatin,extracellular region|extracellular space|cytoplasm|,"transforming growth factor beta receptor signaling pathway|negative regulation of muscle hypertrophy|growth|positive regulation of transcription, DNA-templated|negative regulation of skeletal muscle tissue growth|cellular response to dexamethasone stimulus|",receptor binding|receptor binding|receptor binding|cytokine activity|protein binding|growth factor activity|heparin binding|identical protein binding|,10,-0.1,0.199,10,-0.1,0.366,-0.1,0.516,-0.516,0.667,0,0,-1.7,1.1
ENSMUSG00000064140,TRIM38,tripartite motif-containing 38,cellular_component|,signal transduction|regulation of interferon-beta production|regulation of interferon-beta production|positive regulation of I-kappaB kinase/NF-kappaB signaling|proteasome-mediated ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of viral genome replication|positive regulation of viral genome replication|positive regulation of viral entry into host cell|negative regulation of defense response to virus|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|protein K48-linked ubiquitination|protein K48-linked ubiquitination|,signal transducer activity|protein binding|metal ion binding|,9,0.4,0.418,9,-0.3,1.37,-0.2,0.515,-0.515,0.667,0,0,-1.5,1.4
ENSMUSG00000023132,GZMA,granzyme A,extracellular region|nucleus|,proteolysis|apoptotic process|cytolysis|negative regulation of endodeoxyribonuclease activity|positive regulation of apoptotic process|negative regulation of DNA binding|negative regulation of oxidoreductase activity|proteolysis involved in cellular protein catabolic process|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|protein homodimerization activity|,10,-0.1,0.00456,10,-0.2,0.591,-0.1,0.514,-0.514,0.667,0,0,-1.7,1.2
ENSMUSG00000032020,UBASH3B,"ubiquitin associated and SH3 domain containing, B",cellular_component|nucleus|cytoplasm|,negative regulation of protein kinase activity|peptidyl-tyrosine dephosphorylation|regulation of release of sequestered calcium ion into cytosol|negative regulation of platelet aggregation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein binding|hydrolase activity|,10,0.2,0.657,10,0.1,0.0863,0.2,0.512,0.512,0.668,0,0,-1,1.8
ENSMUSG00000043310,OLFR571,olfactory receptor 571,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.8,2.51,10,-0.1,0.0146,-0.1,0.512,-0.512,0.668,0,0,-2,0.6
ENSMUSG00000003200,SH3GL1,SH3-domain GRB2-like 1,cytoplasm|endosome|membrane|cell junction|cell projection|,endocytosis|,protein binding|lipid binding|phosphatase binding|identical protein binding|GTPase binding|,10,0.2,0.887,10,0,0,0.1,0.511,0.511,0.668,0,0,-0.8,1.9
ENSMUSG00000070822,ZSCAN18,zinc finger and SCAN domain containing 18,nucleus|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|,sequence-specific DNA binding RNA polymerase II transcription factor activity|metal ion binding|,10,-0.3,0.286,10,0.2,0.667,0.1,0.506,0.506,0.669,0,0,-1.5,1.4
ENSMUSG00000033720,SFXN5,sideroflexin 5,mitochondrion|mitochondrion|mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|citrate transport|tricarboxylic acid transmembrane transport|iron ion homeostasis|transmembrane transport|,cation transmembrane transporter activity|citrate transmembrane transporter activity|,10,-0.3,0.747,10,0,0,-0.2,0.506,-0.506,0.669,0,0,-1.5,1.3
ENSMUSG00000032733,SNX33,sorting nexin 33,cytoplasm|endosome|membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic membrane-bounded vesicle|extrinsic component of membrane|cytoplasmic vesicle|,mitotic cytokinesis|transport|intracellular protein transport|endocytosis|endosome organization|cell cycle|mitotic nuclear division|protein transport|endosomal transport|cleavage furrow formation|macropinocytosis|cell division|membrane tubulation|,phosphatidylinositol binding|identical protein binding|,10,-0.1,0.0931,10,0.4,1.31,0.2,0.505,0.505,0.67,0,0,-0.9,1.8
ENSMUSG00000035126,WDR78,WD repeat domain 78,cellular_component|,hematopoietic progenitor cell differentiation|,molecular_function|,10,-0.1,0.331,10,0.4,0.521,-0.1,0.502,-0.502,0.67,0,0,-1.4,1.6
ENSMUSG00000048015,NEUROD4,neurogenic differentiation 4,nucleus|,"neuron migration|neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|Notch signaling pathway|multicellular organismal development|nervous system development|neuroblast proliferation|glial cell differentiation|cell differentiation|amacrine cell differentiation|camera-type eye development|cell fate commitment|positive regulation of cell differentiation|positive regulation of cell differentiation|neuron development|",DNA binding|protein dimerization activity|,10,-0.2,0.776,10,0,0,-0.1,0.502,-0.502,0.67,0,0,-1.9,0.8
ENSMUSG00000048232,FBXO10,F-box protein 10,cytoplasm|,apoptotic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of apoptotic process|,molecular_function|,10,0.3,1.17,10,0,0,0.2,0.501,0.501,0.671,0,0,-0.8,1.9
ENSMUSG00000078676,CASC3,cancer susceptibility candidate 3,nucleus|cytoplasm|ribonucleoprotein complex|exon-exon junction complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|mRNA processing|regulation of translation|transport|response to stress|intracellular mRNA localization|RNA splicing|mRNA transport|",RNA binding|protein binding|enzyme binding|ubiquitin protein ligase binding|identical protein binding|poly(A) RNA binding|,10,-0.3,1.99,9,0.1,0.221,-0.2,0.5,-0.5,0.671,0,0,-1.5,1.4
ENSMUSG00000038495,OTUD7B,OTU domain containing 7B,nucleus|cytoplasm|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|immune system process|mucosal immune response|proteolysis|protein deubiquitination|negative regulation of interleukin-8 production|protein K11-linked deubiquitination|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|protein K63-linked deubiquitination|protein K48-linked deubiquitination|protein K48-linked deubiquitination|negative regulation of protein localization to nucleus|,DNA binding|ubiquitin thiolesterase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|metal ion binding|K63-linked polyubiquitin binding|Lys48-specific deubiquitinase activity|,9,-0.2,0.694,9,0.5,1.62,0.3,0.5,0.5,0.671,0,0,-1.3,1.6
ENSMUSG00000020698,CCT6B,"chaperonin containing Tcp1, subunit 6b (zeta)",cytoplasm|chaperonin-containing T-complex|,protein folding|biological_process|cellular protein metabolic process|,nucleotide binding|molecular_function|ATP binding|unfolded protein binding|,10,0.2,0.753,10,-0.2,0.102,-0.2,0.5,-0.5,0.671,0,0,-1.4,1.3
ENSMUSG00000040396,ABHD13,abhydrolase domain containing 13,membrane|membrane|integral component of membrane|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.4,1.57,10,1.1,1.94,-0.2,0.499,-0.499,0.671,0,0,-1,2
ENSMUSG00000001025,S100A6,S100 calcium binding protein A6 (calcyclin),ruffle|nucleus|nuclear envelope|cytoplasm|cytosol|plasma membrane|membrane|extrinsic component of cytoplasmic side of plasma membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,ion transmembrane transport|,calcium ion binding|calcium ion binding|protein binding|tropomyosin binding|zinc ion binding|ion transmembrane transporter activity|protein homodimerization activity|S100 protein binding|metal ion binding|calcium-dependent protein binding|,10,0.2,0.482,10,0.1,0.14,0.2,0.496,0.496,0.672,0,0,-0.9,1.9
ENSMUSG00000092607,SCNM1,sodium channel modifier 1,nucleus|,mRNA processing|RNA splicing|,enzyme binding|metal ion binding|,10,-0.2,0.568,10,0.2,0.408,-0.1,0.494,-0.494,0.673,0,0,-1.4,1.4
ENSMUSG00000021715,CWC27,CWC27 spliceosome-associated protein homolog (S. cerevisiae),nucleus|catalytic step 2 spliceosome|,protein peptidyl-prolyl isomerization|protein folding|,peptidyl-prolyl cis-trans isomerase activity|isomerase activity|,10,-0.5,1.22,10,0.1,0.00394,-0.4,0.492,-0.492,0.673,0,0,-1.8,0.8
ENSMUSG00000074238,AP1AR,adaptor-related protein complex 1 associated regulatory protein,nucleolus|cytoplasm|endosome|Golgi apparatus|transport vesicle|,"negative regulation of receptor recycling|regulation of Arp2/3 complex-mediated actin nucleation|regulation of Arp2/3 complex-mediated actin nucleation|cellular protein localization|vesicle targeting, trans-Golgi to endosome|negative regulation of substrate adhesion-dependent cell spreading|negative regulation of substrate adhesion-dependent cell spreading|negative regulation of cell motility|",kinesin binding|AP-1 adaptor complex binding|Arp2/3 complex binding|,10,0.2,0.665,10,0.1,0.013,0.1,0.492,0.492,0.673,0,0,-1.3,1.6
ENSMUSG00000050730,ARHGAP42,Rho GTPase activating protein 42,intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,0.2,0.917,10,0,0,0.2,0.49,0.49,0.674,0,0,-0.9,1.9
ENSMUSG00000063887,NLGN1,neuroligin 1,intracellular|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|external side of plasma membrane|cell surface|cell surface|cell surface|membrane|integral component of membrane|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|dendrite|filopodium tip|synapse|synapse|postsynaptic membrane|excitatory synapse|,"regulation of respiratory gaseous exchange by neurological system process|protein targeting|cell adhesion|heterophilic cell-cell adhesion|neuron cell-cell adhesion|neuron cell-cell adhesion|nervous system development|synapse assembly|synapse assembly|synaptic vesicle targeting|calcium-dependent cell-cell adhesion|calcium-dependent cell-cell adhesion|positive regulation of synaptic transmission, GABAergic|protein localization to synapse|establishment of protein localization|regulation of neuron differentiation|cytoskeletal matrix organization at active zone|cytoskeletal matrix organization at active zone|regulation of synaptic transmission|synapse organization|synapse organization|protein homooligomerization|protein heterotetramerization|positive regulation of filopodium assembly|positive regulation of synapse assembly|positive regulation of synapse assembly|positive regulation of synaptic transmission, glutamatergic|positive regulation of dendritic spine development|terminal button organization|terminal button organization|synaptic vesicle clustering|synaptic vesicle clustering|postsynaptic membrane assembly|presynaptic membrane assembly|presynaptic membrane assembly|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|N-methyl-D-aspartate receptor clustering|neurexin clustering|postsynaptic density protein 95 clustering|postsynaptic density protein 95 clustering|receptor localization to synapse|positive regulation of ruffle assembly|positive regulation of synaptic vesicle endocytosis|positive regulation of synaptic vesicle endocytosis|positive regulation of intracellular signal transduction|positive regulation of synaptic vesicle exocytosis|positive regulation of synaptic vesicle exocytosis|regulation of N-methyl-D-aspartate selective glutamate receptor activity|regulation of N-methyl-D-aspartate selective glutamate receptor activity|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|positive regulation of excitatory postsynaptic membrane potential|positive regulation of excitatory postsynaptic membrane potential|",receptor activity|receptor activity|protein binding|PDZ domain binding|neurexin family protein binding|neurexin family protein binding|neurexin family protein binding|protein dimerization activity|cell adhesion molecule binding|,10,-0.3,0.424,10,0.7,1.51,0.1,0.488,0.488,0.675,0,0,-0.9,1.9
ENSMUSG00000022372,SLA,src-like adaptor,cytoplasm|endosome|,None,protein binding|,10,0.1,0.473,10,0.3,0.161,0.1,0.488,0.488,0.675,0,0,-1.1,1.7
ENSMUSG00000071660,TTC9C,tetratricopeptide repeat domain 9C,endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|,10,-0.2,0.858,10,0,0,-0.1,0.483,-0.483,0.676,0,0,-1.4,1.6
ENSMUSG00000035187,NKX6-1,NK6 homeobox 1,nucleus|nucleus|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|smoothened signaling pathway|multicellular organismal development|cell proliferation|regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification|regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification|central nervous system neuron differentiation|neurogenesis|cell differentiation|cell differentiation|regulation of axon extension|endocrine pancreas development|endocrine pancreas development|positive regulation of insulin secretion|positive regulation of neuron differentiation|negative regulation of glial cell differentiation|positive regulation of glial cell differentiation|oligodendrocyte differentiation|regulation of neuron migration|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.3,0.433,10,-0.8,0.43,-0.3,0.479,-0.479,0.677,0,0,-2,0.7
ENSMUSG00000031828,KLHL36,kelch-like 36,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.22,10,0,0,-0.2,0.477,-0.477,0.678,0,0,-1.6,1.3
ENSMUSG00000022244,AMACR,alpha-methylacyl-CoA racemase,cytoplasm|mitochondrion|mitochondrion|peroxisome|,bile acid biosynthetic process|bile acid metabolic process|isoprenoid catabolic process|,catalytic activity|receptor binding|alpha-methylacyl-CoA racemase activity|alpha-methylacyl-CoA racemase activity|isomerase activity|,10,0,0,10,1,1.6,0.2,0.475,0.475,0.678,0,0,-0.8,2
ENSMUSG00000002076,HSF2BP,heat shock transcription factor 2 binding protein,cytosol|,biological_process|,protein binding|,10,0.3,0.098,10,-0.3,0.822,-0.3,0.472,-0.472,0.68,0,0,-1.4,1.6
ENSMUSG00000020097,SGPL1,sphingosine phosphate lyase 1,endoplasmic reticulum|membrane|integral component of membrane|,luteinization|vasculogenesis|kidney development|lipid metabolic process|fatty acid metabolic process|sphingolipid metabolic process|ceramide metabolic process|nitrogen compound metabolic process|apoptotic process|spermatogenesis|androgen metabolic process|estrogen metabolic process|female gonad development|post-embryonic development|fibroblast migration|carboxylic acid metabolic process|hemopoiesis|sphingolipid catabolic process|Leydig cell differentiation|regulation of multicellular organism growth|platelet-derived growth factor receptor signaling pathway|skeletal system morphogenesis|palate development|face morphogenesis|execution phase of apoptosis|,catalytic activity|sphinganine-1-phosphate aldolase activity|lyase activity|carboxy-lyase activity|pyridoxal phosphate binding|,10,-0.2,0.31,10,0.2,0.699,0.2,0.469,0.469,0.681,0,0,-1.3,1.5
ENSMUSG00000025823,PDIA4,protein disulfide isomerase associated 4,endoplasmic reticulum|endoplasmic reticulum lumen|smooth endoplasmic reticulum|cell surface|cell surface|,protein folding|response to endoplasmic reticulum stress|cell redox homeostasis|chaperone-mediated protein folding|,protein disulfide isomerase activity|protein disulfide isomerase activity|isomerase activity|poly(A) RNA binding|,10,-1,2.37,10,0,0,-0.4,0.463,-0.463,0.682,0,0,-2,0.4
ENSMUSG00000040701,AP1G2,"adaptor protein complex AP-1, gamma 2 subunit",endosome|Golgi apparatus|Golgi-associated vesicle|trans-Golgi network|membrane|membrane coat|clathrin adaptor complex|transport vesicle|cytoplasmic vesicle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,protein binding|protein transporter activity|,10,0.4,1.45,10,-0.2,0.0228,0.3,0.462,0.462,0.683,0,0,-1.1,1.8
ENSMUSG00000033182,KBTBD12,kelch repeat and BTB (POZ) domain containing 12,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.399,10,-0.1,0.105,-0.1,0.461,-0.461,0.683,0,0,-1.7,1.2
ENSMUSG00000048486,FITM2,fat storage-inducing transmembrane protein 2,mitochondrion|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,cytoskeleton organization|regulation of triglyceride biosynthetic process|positive regulation of sequestering of triglyceride|regulation of cell morphogenesis|lipid particle organization|lipid particle organization|cellular triglyceride homeostasis|,molecular_function|,10,-0.2,0.00885,9,0.3,1.03,0.2,0.458,0.458,0.684,0,0,-1.4,1.4
ENSMUSG00000066026,DHRS3,dehydrogenase/reductase (SDR family) member 3,membrane|integral component of membrane|,retinoid metabolic process|outflow tract morphogenesis|metabolic process|regulation of ossification|negative regulation of retinoic acid receptor signaling pathway|oxidation-reduction process|palate development|bone morphogenesis|cardiac septum morphogenesis|,retinol dehydrogenase activity|oxidoreductase activity|NADP-retinol dehydrogenase activity|,10,0.2,0.49,10,0.1,0.0195,0.2,0.458,0.458,0.684,0,0,-0.9,1.8
ENSMUSG00000003070,EFNA2,ephrin A2,plasma membrane|membrane|anchored component of membrane|neuromuscular junction|perikaryon|,axon guidance|osteoclast differentiation|osteoclast differentiation|bone remodeling|bone remodeling|ephrin receptor signaling pathway|ephrin receptor signaling pathway|,protein binding|ephrin receptor binding|ephrin receptor binding|,9,0.2,0.403,9,0.1,0.132,0.1,0.458,0.458,0.684,0,0,-1.1,1.8
ENSMUSG00000029685,ASB15,ankyrin repeat and SOCS box-containing 15,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,-0.2,0.63,10,-0.8,0.255,-0.1,0.454,-0.454,0.685,0,0,-2,0.7
ENSMUSG00000045631,TMPRSS12,"transmembrane (C-terminal) protease, serine 12",cellular_component|membrane|integral component of membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,0.546,10,-0.1,0.0237,-0.1,0.454,-0.454,0.685,0,0,-1.7,1.1
ENSMUSG00000037406,HTRA4,HtrA serine peptidase 4,cellular_component|extracellular region|,regulation of cell growth|proteolysis|,catalytic activity|endopeptidase activity|serine-type endopeptidase activity|insulin-like growth factor binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,0.848,10,0,0,-0.1,0.449,-0.449,0.687,0,0,-1.7,1.1
ENSMUSG00000024442,0610009O20RIK,RIKEN cDNA 0610009O20 gene,mitochondrion|mitochondrion|,extrinsic apoptotic signaling pathway via death domain receptors|regulation of cysteine-type endopeptidase activity involved in apoptotic process|,molecular_function|,10,0.1,0.158,10,0.2,0.4,0.1,0.448,0.448,0.687,0,0,-1,1.8
ENSMUSG00000022871,FETUB,fetuin beta,extracellular region|extracellular space|,single fertilization|binding of sperm to zona pellucida|negative regulation of peptidase activity|negative regulation of endopeptidase activity|,enzyme inhibitor activity|cysteine-type endopeptidase inhibitor activity|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.6,1.27,10,0,0,-0.2,0.443,-0.443,0.689,0,0,-1.9,1
ENSMUSG00000032268,TMPRSS5,"transmembrane protease, serine 5 (spinesin)",plasma membrane|membrane|integral component of membrane|neuronal cell body|,proteolysis|,catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.3,1.67,10,0,0,-0.2,0.435,-0.435,0.692,0,0,-1.4,1.5
ENSMUSG00000039483,ASB6,ankyrin repeat and SOCS box-containing 6,cellular_component|cytoplasm|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,0.2,0.62,0.1,0.435,0.435,0.692,0,0,-1.2,1.6
ENSMUSG00000034161,SCX,scleraxis,nucleus|nucleus|transcription factor complex|transcription factor complex|,"mesoderm formation|tissue homeostasis|endochondral ossification|chondrocyte differentiation|heart valve morphogenesis|heart valve formation|transcription, DNA-templated|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of gene expression|cell differentiation|collagen fibril organization|BMP signaling pathway|positive regulation of collagen biosynthetic process|positive regulation of collagen biosynthetic process|skeletal muscle cell differentiation|tendon development|tendon cell differentiation|tendon formation|deltoid tuberosity development|negative regulation of apoptotic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cartilage development|regulation of cartilage development|positive regulation of cartilage development|positive regulation of gastrulation|",DNA binding|protein binding|bHLH transcription factor binding|bHLH transcription factor binding|sequence-specific DNA binding|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|E-box binding|E-box binding|E-box binding|,10,0.5,0.894,10,0.1,0.104,0.2,0.432,0.432,0.693,0,0,-1.1,1.7
ENSMUSG00000068856,SF3B4,"splicing factor 3b, subunit 4",nucleus|spliceosomal complex|U12-type spliceosomal complex|,mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,8,-0.2,0.634,5,0,0,-0.2,0.43,-0.43,0.693,0,0,-2,1.1
ENSMUSG00000034416,PKD1L2,polycystic kidney disease 1 like 2,membrane|integral component of membrane|,neuropeptide signaling pathway|detection of mechanical stimulus|calcium ion transmembrane transport|,G-protein alpha-subunit binding|calcium channel activity|calcium ion binding|carbohydrate binding|,10,0.3,1.26,10,-1.4,1.68,0.2,0.429,0.429,0.694,0,0,-3,1.2
ENSMUSG00000030022,ADAMTS9,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9",extracellular region|proteinaceous extracellular matrix|extracellular space|,proteolysis|proteolysis|positive regulation of melanocyte differentiation|regulation of developmental pigmentation|,endopeptidase activity|metallopeptidase activity|,10,-0.2,0.0821,10,0.6,0.826,-0.2,0.429,-0.429,0.694,0,0,-1.1,1.7
ENSMUSG00000015461,ATF6B,activating transcription factor 6 beta,intracellular|nucleus|endoplasmic reticulum|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|response to unfolded protein|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.1,0.146,10,-0.8,0.905,-0.2,0.427,-0.427,0.694,0,0,-2,0.6
ENSMUSG00000030967,ZRANB1,"zinc finger, RAN-binding domain containing 1",nucleus|cytoplasm|,proteolysis|cytoskeleton organization|Wnt signaling pathway|cell migration|regulation of cell morphogenesis|positive regulation of Wnt signaling pathway|protein K29-linked deubiquitination|protein K63-linked deubiquitination|protein deubiquitination involved in ubiquitin-dependent protein catabolic process|protein K33-linked deubiquitination|,ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|metal ion binding|K63-linked polyubiquitin binding|,10,-0.3,0.543,10,-0.1,0.0552,-0.2,0.425,-0.425,0.695,0,0,-1.7,1.1
ENSMUSG00000026754,GOLGA1,"golgi autoantigen, golgin subfamily a, 1",Golgi apparatus|Golgi apparatus|trans-Golgi network|membrane|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,protein targeting to Golgi|biological_process|,protein binding|,10,-0.3,1.11,10,0,0,-0.1,0.416,-0.416,0.698,0,0,-1.6,1.2
ENSMUSG00000062077,TRIM54,tripartite motif-containing 54,intracellular|cytoplasm|cytoskeleton|microtubule|microtubule associated complex|,negative regulation of microtubule depolymerization|multicellular organismal development|cell differentiation|,microtubule binding|zinc ion binding|metal ion binding|,10,0.1,0.148,10,-0.3,0.691,-0.2,0.415,-0.415,0.698,0,0,-1.6,1.1
ENSMUSG00000056900,USP13,ubiquitin specific peptidase 13 (isopeptidase T-3),cellular_component|,"regulation of transcription, DNA-templated|proteolysis|ubiquitin-dependent protein catabolic process|autophagy|cell proliferation|regulation of autophagy|protein stabilization|protein K63-linked deubiquitination|",cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|omega peptidase activity|zinc ion binding|hydrolase activity|ubiquitin protein ligase binding|ubiquitinyl hydrolase activity|ubiquitin binding|metal ion binding|,10,-0.3,1.23,10,1,0.245,-0.2,0.414,-0.414,0.698,0,0,-1.1,1.9
ENSMUSG00000043144,AQP6,aquaporin 6,integral component of plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|pore complex|,transport|ion transport|water transport|nitrate transport|ion transmembrane transport|transmembrane transport|,transporter activity|anion channel activity|nitrate transmembrane transporter activity|water channel activity|porin activity|,10,0.3,0.311,10,0.1,0.328,0.2,0.412,0.412,0.699,0,0,-0.7,1.9
ENSMUSG00000037270,4932438A13RIK,RIKEN cDNA 4932438A13 gene,nucleus|membrane|integral component of membrane|,regulation of cell growth|lipid metabolic process|spermatogenesis|lipid storage|fat cell differentiation|nucleus localization|adipose tissue development|,molecular_function|,10,0.2,0.179,10,0.1,0.389,0.2,0.41,0.41,0.7,0,0,-1.5,1.4
ENSMUSG00000075273,TTC30B,tetratricopeptide repeat domain 30B,intracellular|cell|cilium|cilium|intraciliary transport particle B|ciliary basal body|cell projection|,cell projection organization|intraciliary transport|intraciliary transport|cilium assembly|,molecular_function|,10,0.2,0.279,10,0.2,0.169,0.2,0.409,0.409,0.7,0,0,-1.1,1.6
ENSMUSG00000034255,ARHGAP27,Rho GTPase activating protein 27,intracellular|cytoplasm|endosome|membrane|,endocytosis|receptor-mediated endocytosis|signal transduction|positive regulation of Rac GTPase activity|positive regulation of Cdc42 GTPase activity|,GTPase activator activity|SH3 domain binding|Rac GTPase activator activity|,10,0,0,9,-0.2,0.489,-0.1,0.408,-0.408,0.7,0,0,-1.6,1.4
ENSMUSG00000027833,SHOX2,short stature homeobox 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|osteoblast differentiation|positive regulation of mesenchymal cell proliferation|chondrocyte differentiation|chondrocyte development|heart valve development|cardiac atrium morphogenesis|regulation of transcription, DNA-templated|multicellular organismal development|embryonic limb morphogenesis|regulation of chondrocyte differentiation|embryonic forelimb morphogenesis|positive regulation of smoothened signaling pathway|positive regulation of transcription from RNA polymerase II promoter|embryonic digestive tract morphogenesis|embryonic morphogenesis|positive regulation of skeletal muscle fiber development|positive regulation of axonogenesis|embryonic skeletal joint morphogenesis|cartilage development involved in endochondral bone morphogenesis|muscle tissue morphogenesis|regulation of branching morphogenesis of a nerve|",DNA binding|sequence-specific DNA binding|,10,-0.2,0.65,10,0,0,-0.1,0.406,-0.406,0.701,0,0,-1.7,1
ENSMUSG00000041702,BTBD7,BTB (POZ) domain containing 7,nucleus|,multicellular organismal development|regulation of branching involved in salivary gland morphogenesis|,molecular_function|,10,-0.2,1.07,10,0.4,1.25,-0.1,0.401,-0.401,0.703,0,0,-1.3,1.4
ENSMUSG00000073987,GGH,gamma-glutamyl hydrolase,extracellular region|extracellular space|nucleus|lysosome|cytosol|extracellular vesicular exosome|,proteolysis|proteolysis|glutamine metabolic process|response to zinc ion|response to insulin|response to drug|response to ethanol|,catalytic activity|peptidase activity|omega peptidase activity|hydrolase activity|gamma-glutamyl-peptidase activity|,10,-0.7,1.81,10,0.1,0.151,-0.3,0.4,-0.4,0.703,0,0,-1.9,1.2
ENSMUSG00000030144,CLEC4D,"C-type lectin domain family 4, member d",membrane|integral component of membrane|,immune system process|innate immune response|,carbohydrate binding|,10,-0.1,0.147,10,-0.2,0.349,-0.2,0.399,-0.399,0.703,0,0,-1.7,1
ENSMUSG00000026692,FMO4,flavin containing monooxygenase 4,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,drug catabolic process|oxidation-reduction process|,"monooxygenase activity|N,N-dimethylaniline monooxygenase activity|oxidoreductase activity|flavin adenine dinucleotide binding|NADP binding|",10,0,0,10,-0.2,0.996,-0.1,0.399,-0.399,0.703,0,0,-1.3,1.6
ENSMUSG00000057367,BIRC2,baculoviral IAP repeat-containing 2,XY body|nucleus|cytoplasm|cytoplasmic side of plasma membrane|CD40 receptor complex|protein complex|membrane raft|,"protein polyubiquitination|response to hypoxia|placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|regulation of apoptotic process|negative regulation of apoptotic process|proteasome-mediated ubiquitin-dependent protein catabolic process|protein heterooligomerization|regulation of cell cycle|regulation of necroptotic process|negative regulation of necroptotic process|necroptotic process|negative regulation of ripoptosome assembly involved in necroptotic process|positive regulation of protein K63-linked ubiquitination|positive regulation of protein K48-linked ubiquitination|positive regulation of protein monoubiquitination|regulation of reactive oxygen species metabolic process|regulation of RNA biosynthetic process|","transcription coactivator activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein N-terminus binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.151,10,-0.3,0.759,-0.2,0.396,-0.396,0.704,0,0,-1.3,1.6
ENSMUSG00000067851,ARFGEF1,ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited),Golgi membrane|nucleus|cytoplasm|Golgi apparatus|trans-Golgi network|trans-Golgi network|cytosol|membrane|small nuclear ribonucleoprotein complex|perinuclear region of cytoplasm|,transport|Golgi organization|endomembrane system organization|protein transport|vesicle-mediated transport|negative regulation of actin filament polymerization|regulation of ARF protein signal transduction|negative regulation of Rho GTPase activity|positive regulation of GTPase activity|positive regulation of GTPase activity|positive regulation of protein glycosylation in Golgi|positive regulation of wound healing|regulation of establishment of cell polarity|,guanyl-nucleotide exchange factor activity|ARF guanyl-nucleotide exchange factor activity|myosin binding|protein kinase A regulatory subunit binding|,10,0.5,0.917,10,-0.2,0.279,0.1,0.396,0.396,0.704,0,0,-1.1,1.6
ENSMUSG00000027883,GPSM2,"G-protein signalling modulator 2 (AGS3-like, C. elegans)",cell|nucleus|cytoplasm|apical part of cell|,establishment of mitotic spindle orientation|lung epithelial cell differentiation|,protein binding|GTPase regulator activity|identical protein binding|,10,-0.1,0.0859,10,-0.2,0.41,-0.1,0.395,-0.395,0.704,0,0,-1.3,1.6
ENSMUSG00000018481,APPBP2,amyloid beta precursor protein (cytoplasmic tail) binding protein 2,nucleus|cytoplasm|cytoskeleton|microtubule|membrane|cytoplasmic vesicle membrane|,transport|protein transport|intracellular transport|,protein binding|microtubule binding|,10,-0.2,0.812,10,0.3,0.824,0.3,0.391,0.391,0.706,0,0,-0.8,1.9
ENSMUSG00000003581,RNF215,ring finger protein 215,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.1,0.0758,10,-0.2,0.438,-0.1,0.391,-0.391,0.706,0,0,-1.9,1
ENSMUSG00000061615,HIST1H2AB,"histone cluster 1, H2ab",nucleus|extracellular vesicular exosome|,None,None,9,-0.3,0.745,9,0.1,0.369,-0.2,0.39,-0.39,0.706,0,0,-1.7,1.1
ENSMUSG00000039007,CPQ,carboxypeptidase Q,extracellular region|extracellular space|cytoplasm|lysosome|endoplasmic reticulum|Golgi apparatus|extracellular vesicular exosome|,proteolysis|thyroid hormone generation|peptide catabolic process|,aminopeptidase activity|carboxypeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|protein homodimerization activity|metal ion binding|metallodipeptidase activity|,10,0,0,9,0.3,0.775,0.2,0.389,0.389,0.706,0,0,-1.9,1.2
ENSMUSG00000003948,MMD,monocyte to macrophage differentiation-associated,lysosome|endosome|membrane|integral component of membrane|,cytolysis|,None,10,-0.5,0.588,10,-0.1,0.102,-0.1,0.388,-0.388,0.707,0,0,-1.8,1
ENSMUSG00000031902,NFATC3,"nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3",nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytosol|,"patterning of blood vessels|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|heart development|cellular respiration|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|smooth muscle cell differentiation|muscle cell development|cellular response to calcium ion|cellular response to lithium ion|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.1,0.0363,10,-0.2,0.385,-0.2,0.381,-0.381,0.71,0,0,-1.7,1.1
ENSMUSG00000024519,CPLX4,complexin 4,plasma membrane|membrane|cell junction|synapse|,transport|neurotransmitter transport|exocytosis|regulation of neurotransmitter secretion|,SNARE binding|syntaxin binding|,9,-0.1,0.0633,10,-0.5,1.32,-0.2,0.374,-0.374,0.712,0,0,-1.8,1
ENSMUSG00000032897,NFYC,nuclear transcription factor-Y gamma,intracellular|nucleus|nucleus|transcription factor complex|CCAAT-binding factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0.1,0.104,10,-1.1,1.89,-0.1,0.369,-0.369,0.714,0,0,-2,1.1
ENSMUSG00000020577,TSPAN13,tetraspanin 13,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,1.54,10,-1.2,2.65,0.4,0.369,0.369,0.714,0,0,-2,1.3
ENSMUSG00000010086,RNF112,ring finger protein 112,nucleus|cytoplasm|membrane|integral component of membrane|,positive regulation of neuron differentiation|positive regulation of glial cell differentiation|positive regulation of cell cycle arrest|,molecular_function|GTPase activity|GTP binding|zinc ion binding|metal ion binding|,10,-0.2,0.47,10,0.4,0.947,-0.2,0.366,-0.366,0.715,0,0,-1.4,1.5
ENSMUSG00000024589,NEDD4L,"neural precursor cell expressed, developmentally down-regulated gene 4-like",nucleus|cytoplasm|plasma membrane|extracellular vesicular exosome|,negative regulation of systemic arterial blood pressure|regulation of membrane depolarization|protein monoubiquitination|response to salt stress|response to metal ion|positive regulation of sodium ion transport|negative regulation of sodium ion transport|negative regulation of sodium ion transport|negative regulation of sodium ion transport|protein ubiquitination|protein ubiquitination|regulation of ion transmembrane transport|regulation of membrane potential|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|positive regulation of protein catabolic process|regulation of membrane repolarization|protein K48-linked ubiquitination|ventricular cardiac muscle cell action potential|regulation of potassium ion transmembrane transporter activity|negative regulation of potassium ion transmembrane transporter activity|negative regulation of potassium ion transmembrane transport|negative regulation of sodium ion transmembrane transport|negative regulation of protein localization to cell surface|negative regulation of sodium ion transmembrane transporter activity|regulation of tight junction assembly|positive regulation of cation channel activity|positive regulation of caveolin-mediated endocytosis|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|potassium channel regulator activity|ligase activity|sodium channel regulator activity|ribosomal S6-glutamic acid ligase activity|potassium channel inhibitor activity|sodium channel inhibitor activity|sodium channel inhibitor activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|ion channel binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-1,0.754,10,0.3,0.878,0.2,0.361,0.361,0.717,0,0,-1.9,1.1
ENSMUSG00000035472,SLC25A21,"solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,transport|,molecular_function|,10,0.3,0.804,10,0,0,0.2,0.355,0.355,0.719,0,0,-1.2,1.7
ENSMUSG00000021203,OTUB2,"OTU domain, ubiquitin aldehyde binding 2",nucleus|,proteolysis|cellular amino acid metabolic process|protein deubiquitination|protein metabolic process|protein K11-linked deubiquitination|protein K63-linked deubiquitination|protein K48-linked deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|omega peptidase activity|hydrolase activity|,10,-0.1,0.0666,10,-0.1,0.321,-0.1,0.354,-0.354,0.719,0,0,-1.5,1.4
ENSMUSG00000022076,KLHL1,kelch-like 1,cytoplasm|cytoskeleton|dendrite|neuronal cell body|,locomotory behavior|adult walking behavior|dendrite development|cerebellar Purkinje cell layer development|,actin binding|,10,-0.1,0.0857,10,-0.2,0.43,-0.1,0.354,-0.354,0.719,0,0,-1.3,1.5
ENSMUSG00000005237,DNAH2,"dynein, axonemal, heavy chain 2",cytoplasm|cytoskeleton|microtubule|cilium|dynein complex|cell projection|,microtubule-based movement|,nucleotide binding|motor activity|microtubule motor activity|ATP binding|ATPase activity|,10,0,0,10,-0.2,0.504,-0.1,0.352,-0.352,0.72,0,0,-1.6,1.3
ENSMUSG00000051705,SENP8,SUMO/sentrin specific peptidase 8,cellular_component|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|NEDD8-specific protease activity|,10,0,0,10,-0.2,1.35,-0.1,0.341,-0.341,0.724,0,0,-1.7,1.1
ENSMUSG00000029426,SCARB2,"scavenger receptor class B, member 2",intracellular|cell|lysosome|lysosomal membrane|lysosomal membrane|membrane|membrane|integral component of membrane|lysosomal lumen|extracellular vesicular exosome|,protein targeting to lysosome|protein targeting to lysosome|cell adhesion|,receptor activity|enzyme binding|enzyme binding|,9,-0.1,0.181,10,-0.2,0.217,-0.2,0.34,-0.34,0.724,0,0,-1.8,1.1
ENSMUSG00000015401,TMEM27,transmembrane protein 27,cytoplasm|membrane|integral component of membrane|brush border membrane|extracellular vesicular exosome|,proteolysis|positive regulation of SNARE complex assembly|positive regulation of insulin secretion involved in cellular response to glucose stimulus|positive regulation of calcium ion-dependent exocytosis|positive regulation of amino acid transport|positive regulation of amino acid transport|,protein binding|metallopeptidase activity|peptidyl-dipeptidase activity|,10,-0.1,0.205,10,0.3,0.779,0.1,0.336,0.336,0.725,0,0,-1.3,1.5
ENSMUSG00000040841,SIX5,sine oculis-related homeobox 5,nucleus|,"lens development in camera-type eye|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatid development|negative regulation of cell proliferation|",DNA binding|sequence-specific DNA binding|,9,-0.1,0.0622,9,-0.2,0.383,-0.2,0.334,-0.334,0.726,0,0,-1.5,1.6
ENSMUSG00000060450,RNF14,ring finger protein 14,nucleus|nucleus|cytoplasm|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|response to estradiol|positive regulation of transcription, DNA-templated|regulation of androgen receptor signaling pathway|","zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|small conjugating protein ligase activity|small conjugating protein ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|androgen receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.4,0.813,0.2,0.334,0.334,0.726,0,0,-0.9,1.8
ENSMUSG00000039853,TRIM14,tripartite motif-containing 14,intracellular|cytoplasm|,negative regulation of viral transcription|innate immune response|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|,molecular_function|zinc ion binding|metal ion binding|,10,0.1,0.029,10,-0.4,0.999,-0.1,0.333,-0.333,0.726,0,0,-1.7,1.1
ENSMUSG00000044139,PRSS53,"protease, serine 53",cellular_component|extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.0282,10,-0.1,0.332,-0.1,0.33,-0.33,0.727,0,0,-2,0.9
ENSMUSG00000001520,NRIP2,nuclear receptor interacting protein 2,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|",aspartic-type endopeptidase activity|protein binding|,10,0,0,10,1.1,1.81,0.1,0.329,0.329,0.728,0,0,-0.5,2
ENSMUSG00000021326,TRIM27,tripartite motif-containing 27,intracellular|nucleus|nucleoplasm|cytoplasm|cytoplasm|endosome|retromer complex|nuclear membrane|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of adaptive immune response|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of protein kinase activity|transport|negative regulation of tumor necrosis factor production|negative regulation of viral transcription|negative regulation of viral transcription|Arp2/3 complex-mediated actin nucleation|retrograde transport, endosome to Golgi|innate immune response|innate immune response|negative regulation of gene expression, epigenetic|positive regulation of sequence-specific DNA binding transcription factor activity|protein trimerization|protein K63-linked ubiquitination|interferon-gamma secretion|negative regulation of calcium ion import|negative regulation of interleukin-2 secretion|negative regulation of viral release from host cell|","DNA binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,-0.4,1.13,9,0.1,0.00976,-0.1,0.329,-0.329,0.728,0,0,-1.6,1.3
ENSMUSG00000022957,ITSN1,intersectin 1 (SH3 domain protein 1A),plasma membrane|coated pit|membrane|lamellipodium|cell junction|endocytic vesicle|cell projection|neuron projection|synapse|,endocytosis|small GTPase mediated signal transduction|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of phosphorylation|positive regulation of catalytic activity|negative regulation of neuron apoptotic process|positive regulation of protein kinase B signaling|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|calcium ion binding|protein binding|kinase activator activity|protein complex scaffold|metal ion binding|proline-rich region binding|,10,0,0,10,0.4,1.56,0.1,0.328,0.328,0.728,0,0,-1.6,1.5
ENSMUSG00000032336,NPTN,neuroplastin,plasma membrane|membrane|integral component of membrane|,cell adhesion|nervous system development|,None,10,0.1,0.452,10,0,0,0.1,0.327,0.327,0.729,0,0,-1.2,1.6
ENSMUSG00000021392,NOL8,nucleolar protein 8,nucleus|nucleolus|cytoplasm|,DNA replication|rRNA processing|positive regulation of cell growth|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,8,-0.2,0.656,9,0.2,0.314,0.1,0.326,0.326,0.729,0,0,-2,1
ENSMUSG00000031838,IFI30,interferon gamma inducible protein 30,extracellular region|cytoplasm|lysosome|lysosome|plasma membrane|cell junction|intracellular membrane-bounded organelle|,immune system process|antigen processing and presentation of exogenous peptide antigen via MHC class II|antigen processing and presentation of exogenous peptide antigen via MHC class I|negative regulation of fibroblast proliferation|protein stabilization|oxidation-reduction process|,"disulfide oxidoreductase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors|pheophorbide a oxygenase activity|sulfite reductase (coenzyme F420) activity|aflatoxin reductase (coenzyme F420) activity|",9,0.2,0.556,10,0,0,0.2,0.325,0.325,0.73,0,0,-1.2,1.7
ENSMUSG00000022231,SEMA5A,"sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A",membrane|integral component of membrane|extracellular vesicular exosome|,patterning of blood vessels|positive regulation of endothelial cell proliferation|blood vessel endothelial cell proliferation involved in sprouting angiogenesis|negative regulation of cell adhesion|multicellular organismal development|nervous system development|axon guidance|axon guidance|axonal fasciculation|diencephalon development|cell differentiation|positive regulation of actin filament depolymerization|positive regulation of catenin import into nucleus|positive regulation of angiogenesis|branching morphogenesis of an epithelial tube|positive regulation of axon extension involved in axon guidance|negative regulation of axon extension involved in axon guidance|positive chemotaxis|positive regulation of protein kinase B signaling|cell chemotaxis|semaphorin-plexin signaling pathway|positive regulation of extracellular matrix disassembly|signal clustering|signal clustering|negative regulation of endothelial cell apoptotic process|positive regulation of endothelial cell chemotaxis|,receptor activity|axon guidance receptor activity|semaphorin receptor binding|chondroitin sulfate proteoglycan binding|heparan sulfate proteoglycan binding|syndecan binding|,9,0,0,9,0.1,0.378,0.1,0.323,0.323,0.73,0,0,-1.2,1.8
ENSMUSG00000023914,MEP1A,meprin 1 alpha,membrane|integral component of membrane|meprin A complex|extracellular vesicular exosome|,proteolysis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.0315,10,-0.2,0.362,-0.2,0.317,-0.317,0.732,0,0,-1.6,1.2
ENSMUSG00000017760,CTSA,cathepsin A,nucleus|mitochondrion|lysosome|membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,proteolysis|,carboxypeptidase activity|serine-type carboxypeptidase activity|protein binding|peptidase activity|hydrolase activity|,10,0.1,0.0481,10,0.2,0.357,0.1,0.303,0.303,0.737,0,0,-1.2,1.6
ENSMUSG00000033808,TMEM87A,transmembrane protein 87A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.419,10,-0.1,0.093,-0.1,0.303,-0.303,0.737,0,0,-1.3,1.6
ENSMUSG00000031957,CTRB1,chymotrypsinogen B1,extracellular region|cytoplasm|lysosome|,proteolysis|proteolysis|digestion|protein catabolic process|response to cytokine|positive regulation of apoptotic process|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.493,10,-0.7,0.537,0.1,0.3,0.3,0.739,0,0,-1.9,1.1
ENSMUSG00000028012,RRH,retinal pigment epithelium derived rhodopsin homolog,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|visual perception|phototransduction|protein-chromophore linkage|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|photoreceptor activity|,10,-0.1,0.0388,10,-0.4,0.66,-0.1,0.3,-0.3,0.739,0,0,-1.8,1
ENSMUSG00000044231,NHLRC1,NHL repeat containing 1,nucleus|nucleus|endoplasmic reticulum|perinuclear region of cytoplasm|,protein polyubiquitination|autophagy|protein ubiquitination|positive regulation of protein ubiquitination|proteasome-mediated ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.147,10,0.2,0.252,0.2,0.3,0.3,0.739,0,0,-1,1.7
ENSMUSG00000006538,IHH,Indian hedgehog,extracellular region|plasma membrane|membrane|extracellular matrix|,skeletal system development|skeletal system development|ossification|patterning of blood vessels|osteoblast differentiation|in utero embryonic development|cell fate specification|morphogenesis of a branching structure|vasculature development|heart looping|positive regulation of mesenchymal cell proliferation|epithelial cell morphogenesis|retinal pigment epithelium development|proteoglycan metabolic process|proteolysis|cell communication|smoothened signaling pathway|smoothened signaling pathway|cell-cell signaling|multicellular organismal development|pattern specification process|positive regulation of cell proliferation|positive regulation of cell proliferation|embryo development|embryonic pattern specification|negative regulation of signal transduction|intein-mediated protein splicing|cell differentiation|vitelline membrane formation|pancreas development|pancreas development|positive regulation of chondrocyte differentiation|positive regulation of collagen biosynthetic process|negative regulation of T cell differentiation in thymus|negative regulation of immature T cell proliferation in thymus|positive regulation of T cell differentiation in thymus|multicellular organism growth|chondrocyte proliferation|regulation of growth|camera-type eye development|negative regulation of apoptotic process|bone resorption|regulation of cell differentiation|negative regulation of cell differentiation|positive regulation of smoothened signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T cell differentiation|negative regulation of eye pigmentation|cell maturation|embryonic digestive tract morphogenesis|embryonic camera-type eye morphogenesis|neuron development|smooth muscle tissue development|positive regulation of epithelial cell proliferation|cartilage development|camera-type eye photoreceptor cell fate commitment|head morphogenesis|somite development|embryonic skeletal joint development|epithelial cell-cell adhesion|,patched binding|patched binding|calcium ion binding|protein binding|peptidase activity|hydrolase activity|metal ion binding|,10,0,0,10,0.2,0.872,0.1,0.292,0.292,0.742,0,0,-1.3,1.6
ENSMUSG00000025103,BTBD1,BTB (POZ) domain containing 1,cytoplasmic mRNA processing body|cytoplasmic mRNA processing body|cytoplasm|protein complex|,biological_process|,molecular_function|,10,-0.3,0.39,10,-0.1,0.072,-0.1,0.291,-0.291,0.742,0,0,-1.6,1.3
ENSMUSG00000038084,OPA1,optic atrophy 1,mitochondrion|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial intermembrane space|membrane|membrane|integral component of membrane|mitochondrial crista|dendrite|extrinsic component of mitochondrial inner membrane|,neural tube closure|GTP catabolic process|apoptotic process|mitochondrion organization|mitochondrion organization|mitochondrion organization|inner mitochondrial membrane organization|visual perception|mitochondrial fusion|mitochondrial fusion|positive regulation of mitochondrial fusion|positive regulation of neuron maturation|response to stimulus|negative regulation of release of cytochrome c from mitochondria|negative regulation of release of cytochrome c from mitochondria|cellular senescence|positive regulation of dendrite development|negative regulation of intrinsic apoptotic signaling pathway|,nucleotide binding|GTPase activity|protein binding|GTP binding|hydrolase activity|,9,0,0,9,-0.2,0.387,-0.1,0.29,-0.29,0.742,0,0,-1.7,1.3
ENSMUSG00000027677,TTC14,tetratricopeptide repeat domain 14,cellular_component|,biological_process|,RNA binding|protein binding|,10,-0.3,0.647,10,0,0,-0.1,0.29,-0.29,0.742,0,0,-1.3,1.6
ENSMUSG00000024897,APBA1,"amyloid beta (A4) precursor protein binding, family A, member 1",intracellular|cell|nucleus|cytoplasm|Golgi apparatus|plasma membrane|membrane|protein complex|,in utero embryonic development|transport|intracellular protein transport|synaptic transmission|synaptic transmission|locomotory behavior|regulation of gene expression|glutamate secretion|gamma-aminobutyric acid secretion|protein transport|multicellular organism growth|,"beta-amyloid binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|PDZ domain binding|protein complex binding|",10,-0.1,0.379,10,0,0,-0.1,0.29,-0.29,0.742,0,0,-1.7,1.1
ENSMUSG00000034789,RAB24,"RAB24, member RAS oncogene family",cytoplasm|mitochondrion|autophagic vacuole|membrane|,transport|autophagy|small GTPase mediated signal transduction|protein transport|,nucleotide binding|protein binding|GTP binding|,10,0.1,0.0175,10,-0.5,1.27,-0.2,0.285,-0.285,0.744,0,0,-1.8,1
ENSMUSG00000070661,RNF186,ring finger protein 186,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.1,0.0104,10,0.2,0.448,0.1,0.284,0.284,0.745,0,0,-1.5,1.4
ENSMUSG00000033739,FKBPL,FK506 binding protein-like,endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|,10,0.4,0.885,10,-0.2,0.394,0.1,0.284,0.284,0.745,0,0,-1.3,1.6
ENSMUSG00000027761,AADAC,arylacetamide deacetylase (esterase),endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,metabolic process|positive regulation of triglyceride catabolic process|,triglyceride lipase activity|lipase activity|hydrolase activity|serine hydrolase activity|serine hydrolase activity|deacetylase activity|carboxylic ester hydrolase activity|,10,0.2,0.397,10,0.1,0.02,0.1,0.282,0.282,0.745,0,0,-1.1,1.7
ENSMUSG00000026311,ASB1,ankyrin repeat and SOCS box-containing 1,cellular_component|,multicellular organismal development|male genitalia development|intracellular signal transduction|,molecular_function|,10,-0.1,0.121,10,-0.1,0.188,-0.1,0.282,-0.282,0.745,0,0,-1.7,1.1
ENSMUSG00000031662,SNX20,sorting nexin 20,nucleus|cytoplasm|endosome|plasma membrane|membrane|,transport|protein transport|,lipid binding|phosphatidylinositol binding|,10,0.1,0.0556,9,0.5,0.967,0.1,0.279,0.279,0.747,0,0,-1.2,1.7
ENSMUSG00000010376,NEDD8,"neural precursor cell expressed, developmentally down-regulated gene 8",nucleus|nucleus|nucleus|extracellular vesicular exosome|,regulation of transcription from RNA polymerase II promoter|protein localization|response to organic cyclic compound|protein neddylation|protein neddylation|protein neddylation|,protein binding|ubiquitin protein ligase binding|,8,1.2,2.01,5,-0.4,0.0995,-0.3,0.278,-0.278,0.747,0,0,-1.2,2
ENSMUSG00000068117,MEI1,meiosis defective 1,None,meiotic nuclear division|male meiosis I|gamete generation|spermatid development|,None,10,-0.2,0.76,10,0,0,-0.1,0.278,-0.278,0.747,0,0,-1.7,1.1
ENSMUSG00000038068,RNF144B,ring finger protein 144B,cytoplasm|mitochondrion|membrane|integral component of membrane|mitochondrial membrane|,apoptotic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.4,1.46,10,-0.4,1.66,0.1,0.277,0.277,0.748,0,0,-1.3,1.7
ENSMUSG00000043019,EDEM3,"ER degradation enhancer, mannosidase alpha-like 3",endoplasmic reticulum|endoplasmic reticulum lumen|membrane|,glycoprotein catabolic process|response to unfolded protein|proteasome-mediated ubiquitin-dependent protein catabolic process|,"glycoprotein endo-alpha-1,2-mannosidase activity|mannosyl-oligosaccharide 1,2-alpha-mannosidase activity|calcium ion binding|hydrolase activity|",10,0.2,0.511,10,-0.1,0.0521,0.1,0.276,0.276,0.748,0,0,-1.4,1.5
ENSMUSG00000028423,NFX1,"nuclear transcription factor, X-box binding 1",cellular_component|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of MHC class II biosynthetic process|","nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.5,2.78,10,-0.1,0.425,0.5,0.273,0.273,0.749,0,0,-0.6,2
ENSMUSG00000054702,AP1S3,"adaptor-related protein complex AP-1, sigma 3",Golgi apparatus|coated pit|membrane|membrane coat|cytoplasmic vesicle|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,molecular_function|protein transporter activity|,10,0.1,0.476,10,0,0,0.1,0.271,0.271,0.75,0,0,-2,1
ENSMUSG00000024065,EHD3,EH-domain containing 3,intracellular|cell|cytoplasm|endosome|plasma membrane|membrane|endocytic vesicle|perinuclear region of cytoplasm|recycling endosome membrane|,endocytic recycling|protein homooligomerization|protein targeting to plasma membrane|protein targeting to plasma membrane|regulation of cardiac muscle cell membrane potential|regulation of cardiac muscle cell membrane potential|,nucleotide binding|GTPase activity|calcium ion binding|protein binding|ATP binding|GTP binding|metal ion binding|,10,0,0,10,0.2,0.732,0.1,0.266,0.266,0.752,0,0,-1.3,1.6
ENSMUSG00000030519,APBA2,"amyloid beta (A4) precursor protein-binding, family A, member 2",plasma membrane|,in utero embryonic development|transport|synaptic transmission|locomotory behavior|regulation of gene expression|protein transport|multicellular organism growth|,beta-amyloid binding|protein binding|,10,-0.3,0.94,10,0.1,0.0154,-0.3,0.265,-0.265,0.753,0,0,-1.9,0.7
ENSMUSG00000027581,STMN3,stathmin-like 3,cytoplasm|Golgi apparatus|cell projection|neuron projection|perinuclear region of cytoplasm|,regulation of microtubule polymerization or depolymerization|cytoplasmic microtubule organization|neuron projection development|regulation of Rac GTPase activity|negative regulation of Rac protein signal transduction|regulation of cytoskeleton organization|,protein binding|tubulin binding|protein domain specific binding|,9,0.6,2.12,10,-0.2,0.218,-0.1,0.261,-0.261,0.754,0,0,-1,1.8
ENSMUSG00000041347,BDKRB1,"bradykinin receptor, beta 1",plasma membrane|membrane|integral component of membrane|neuron projection|,negative regulation of protein phosphorylation|positive regulation of leukocyte migration|response to stress|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|response to mechanical stimulus|cell migration|sensory perception of pain|negative regulation of cell growth|response to lipopolysaccharide|negative regulation of blood pressure|positive regulation of release of sequestered calcium ion into cytosol|,signal transducer activity|G-protein coupled receptor activity|bradykinin receptor activity|peptide binding|peptide binding|,10,0,0,10,0.3,0.557,0.1,0.26,0.26,0.755,0,0,-1.1,1.7
ENSMUSG00000027533,FABP5,"fatty acid binding protein 5, epidermal",cytoplasm|extracellular vesicular exosome|,glucose metabolic process|lipid metabolic process|phosphatidylcholine biosynthetic process|transport|glucose transport|,transporter activity|fatty acid binding|lipid binding|,10,0.5,1.61,10,0,0,0.1,0.259,0.259,0.755,0,0,-1.4,1.6
ENSMUSG00000070000,FCHO1,FCH domain only 1,plasma membrane|coated pit|membrane|,endocytosis|clathrin coat assembly|clathrin-mediated endocytosis|,AP-2 adaptor complex binding|,10,-0.1,0.0717,10,-0.9,0.868,-0.9,0.259,-0.259,0.755,0,0,-2,0.5
ENSMUSG00000029502,GOLGA3,"golgi autoantigen, golgin subfamily a, 3",Golgi membrane|nucleus|cytoplasm|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|cytosol|membrane|membrane|Golgi transport complex|extrinsic component of Golgi membrane|,multicellular organismal development|spermatogenesis|cell differentiation|,protein binding|,10,0.8,3.05,10,0,0,0.1,0.258,0.258,0.755,0,0,-0.8,2
ENSMUSG00000035352,CCL12,chemokine (C-C motif) ligand 12,extracellular region|extracellular space|intracellular|,MAPK cascade|angiogenesis|monocyte chemotaxis|monocyte chemotaxis|chemotaxis|inflammatory response|inflammatory response|immune response|cytoskeleton organization|regulation of cell shape|cytokine-mediated signaling pathway|lipopolysaccharide-mediated signaling pathway|negative regulation of glial cell apoptotic process|protein kinase B signaling|negative regulation of neuron apoptotic process|astrocyte cell migration|macrophage chemotaxis|cellular response to organic cyclic compound|positive regulation of calcium ion import|negative regulation of natural killer cell chemotaxis|,cytokine activity|chemokine activity|CCR2 chemokine receptor binding|,10,0,0,10,-0.4,0.917,-0.1,0.256,-0.256,0.756,0,0,-1.9,0.9
ENSMUSG00000028495,RPS6,ribosomal protein S6,intracellular|nucleus|nucleolus|cytoplasm|cytoplasm|ribosome|polysome|small ribosomal subunit|membrane|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|dendrite|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|cell body|perinuclear region of cytoplasm|,G1/S transition of mitotic cell cycle|placenta development|T cell proliferation involved in immune response|T cell proliferation involved in immune response|rRNA processing|rRNA processing|translation|activation-induced cell death of T cells|mitotic nuclear division|mitotic cell cycle checkpoint|gastrulation|gastrulation|oogenesis stage|TOR signaling|T cell differentiation in thymus|T cell differentiation in thymus|ribosomal small subunit biogenesis|ribosomal small subunit biogenesis|glucose homeostasis|positive regulation of apoptotic process|negative regulation of apoptotic process|erythrocyte development|,structural constituent of ribosome|protein binding|protein kinase binding|poly(A) RNA binding|,5,0,0,6,0.8,1.59,0.3,0.252,0.252,0.758,0,0,-1.1,2
ENSMUSG00000028385,SNX30,sorting nexin family member 30,cytoplasm|endosome|,transport|intracellular protein transport|apoptotic process|protein transport|,phosphatidylinositol binding|,10,0,0,10,-0.3,0.591,-0.1,0.249,-0.249,0.759,0,0,-2,0.7
ENSMUSG00000026888,GRB14,growth factor receptor bound protein 14,cytoplasm|endosome|Golgi apparatus|plasma membrane|membrane|intracellular membrane-bounded organelle|,signal transduction|insulin receptor signaling pathway|positive regulation of signal transduction|negative regulation of insulin receptor signaling pathway|,SH3/SH2 adaptor activity|protein binding|phosphoprotein binding|,10,0.1,0.186,10,1.2,1.7,0.1,0.247,0.247,0.76,0,0,-0.6,2
ENSMUSG00000026511,SRP9,signal recognition particle 9,"cytoplasm|signal recognition particle, endoplasmic reticulum targeting|ribonucleoprotein complex|signal recognition particle|extracellular vesicular exosome|",SRP-dependent cotranslational protein targeting to membrane|negative regulation of translational elongation|,RNA binding|7S RNA binding|,9,-0.3,1.66,10,0,0,-0.2,0.245,-0.245,0.761,0,0,-1.3,1.7
ENSMUSG00000031605,KLHL2,"kelch-like 2, Mayven",stress fiber|cytoplasm|cytoskeleton|actin cytoskeleton|Cul3-RING ubiquitin ligase complex|cell projection|,protein ubiquitination|,actin binding|protein homodimerization activity|,10,0,0,10,0.5,2.56,0.4,0.243,0.243,0.761,0,0,-0.8,1.8
ENSMUSG00000043013,ONECUT1,"one cut domain, family member 1",nucleus|nucleus|,"liver development|regulation of cell-matrix adhesion|epithelial cell development|glucose metabolic process|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|endoderm development|anatomical structure morphogenesis|cell differentiation|B cell differentiation|positive regulation of cell migration|negative regulation of transforming growth factor beta receptor signaling pathway|pancreas development|pancreas development|endocrine pancreas development|cilium assembly|cell fate commitment|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|spleen development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|,9,-0.2,0.771,9,0,0,-0.1,0.239,-0.239,0.763,0,0,-1.3,1.7
ENSMUSG00000030539,SEMA4B,"sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B",plasma membrane|membrane|integral component of membrane|synapse|postsynaptic membrane|,multicellular organismal development|nervous system development|cell differentiation|,receptor activity|protein binding|,10,0.2,0.414,10,0.1,0.00576,0.1,0.237,0.237,0.764,0,0,-1.5,1.3
ENSMUSG00000007944,TTC9B,tetratricopeptide repeat domain 9B,endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|,10,-0.3,0.558,10,0,0,-0.1,0.236,-0.236,0.764,0,0,-1.7,1.2
ENSMUSG00000056380,GPR50,G-protein-coupled receptor 50,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|melatonin receptor activity|identical protein binding|,10,-0.5,1.59,10,0.1,0.0135,-0.1,0.23,-0.23,0.767,0,0,-2,0.7
ENSMUSG00000028744,PQLC2,PQ loop repeat containing 2,lysosome|lysosomal membrane|membrane|integral component of membrane|integral component of organelle membrane|,transport|amino acid transport|arginine transport|lysine transport|amino acid homeostasis|L-alpha-amino acid transmembrane transport|,arginine transmembrane transporter activity|L-lysine transmembrane transporter activity|,10,-0.3,1.19,10,0.2,1.64,0.1,0.229,0.229,0.767,0,0,-2,0.9
ENSMUSG00000056917,SIPA1,signal-induced proliferation associated gene 1,nucleus|transport vesicle|protein complex|,cellular response to water deprivation|regulation of small GTPase mediated signal transduction|regulation of cell cycle|,GTPase activator activity|protein C-terminus binding|,10,0.3,0.255,10,0.1,0.0262,0.1,0.229,0.229,0.767,0,0,-1.1,1.8
ENSMUSG00000032393,DPP8,dipeptidylpeptidase 8,nucleus|cytoplasm|membrane|,proteolysis|,molecular_function|aminopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.125,10,0.1,0.158,0.1,0.227,0.227,0.768,0,0,-1.2,1.6
ENSMUSG00000042444,FAM63B,"family with sequence similarity 63, member B",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.435,10,0,0,0.1,0.226,0.226,0.768,0,0,-1.3,1.6
ENSMUSG00000003848,NOB1,NIN1/RPN12 binding protein 1 homolog (S. cerevisiae),nucleus|nucleolus|cytoplasm|,visual perception|maturation of SSU-rRNA|ribosomal small subunit biogenesis|,molecular_function|metal ion binding|,6,0.8,1.98,6,-0.2,0.478,0.2,0.224,0.224,0.769,0,0,-1,2
ENSMUSG00000022125,CLN5,"ceroid-lipofuscinosis, neuronal 5",lysosome|lysosome|lysosomal membrane|vacuolar lumen|endoplasmic reticulum|Golgi apparatus|integral component of membrane|perinuclear region of cytoplasm|,signal peptide processing|lysosome organization|lysosomal lumen acidification|visual perception|cell death|neurogenesis|glycosylation|,mannose binding|,10,-0.2,0.534,10,0.1,0.157,-0.1,0.224,-0.224,0.769,0,0,-1.4,1.4
ENSMUSG00000022528,HES1,hairy and enhancer of split 1 (Drosophila),intracellular|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|liver development|embryonic heart tube morphogenesis|outflow tract morphogenesis|regulation of secondary heart field cardioblast proliferation|ventricular septum development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein complex assembly|cell adhesion|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|smoothened signaling pathway|STAT protein import into nucleus|pattern specification process|pattern specification process|positive regulation of cell proliferation|cell migration|telencephalon development|telencephalon development|midbrain-hindbrain boundary morphogenesis|oculomotor nerve development|trochlear nerve development|hindbrain morphogenesis|forebrain radial glial cell differentiation|neural tube development|pituitary gland development|pituitary gland development|adenohypophysis development|lung development|positive regulation of BMP signaling pathway|midbrain development|pancreas development|somatic stem cell maintenance|aorta morphogenesis|ascending aorta morphogenesis|positive regulation of T cell proliferation|auditory receptor cell differentiation|positive regulation of tyrosine phosphorylation of Stat3 protein|auditory receptor cell fate determination|positive regulation of DNA binding|cell fate commitment|negative regulation of cell differentiation|regulation of fat cell differentiation|negative regulation of auditory receptor cell differentiation|negative regulation of neuron differentiation|negative regulation of neuron differentiation|positive regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of mitotic cell cycle, embryonic|lateral inhibition|positive regulation of JAK-STAT cascade|cell maturation|regulation of timing of cell differentiation|thymus development|cell morphogenesis involved in neuron differentiation|positive regulation of astrocyte differentiation|negative regulation of oligodendrocyte differentiation|artery morphogenesis|regulation of neurogenesis|regulation of timing of neuron differentiation|regulation of timing of neuron differentiation|negative regulation of glial cell proliferation|ventricular septum morphogenesis|labyrinthine layer blood vessel development|common bile duct development|negative regulation of stomach neuroendocrine cell differentiation|cardiac neural crest cell development involved in outflow tract morphogenesis|pharyngeal arch artery morphogenesis|cochlea development|cochlea development|vascular smooth muscle cell development|neuronal stem cell maintenance|neuronal stem cell maintenance|negative regulation of pancreatic A cell differentiation|negative regulation of stem cell differentiation|negative regulation of pro-B cell differentiation|negative regulation of forebrain neuron differentiation|negative regulation of inner ear receptor cell differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein homodimerization activity|histone deacetylase binding|sequence-specific DNA binding|protein dimerization activity|N-box binding|,10,0,0,10,-0.3,0.773,-0.1,0.221,-0.221,0.77,0,0,-1.9,0.7
ENSMUSG00000034936,ARL4D,ADP-ribosylation factor-like 4D,intracellular|nucleus|cytoplasm|plasma membrane|membrane|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|molecular_function|GTP binding|,9,0,0,9,-0.4,0.695,-0.1,0.22,-0.22,0.771,0,0,-1.7,1.3
ENSMUSG00000034940,SYNRG,"synergin, gamma",cytoplasm|Golgi apparatus|membrane|clathrin coat of trans-Golgi network vesicle|,transport|endocytosis|biological_process|protein transport|,molecular_function|calcium ion binding|,10,0.1,0.0786,10,0.1,0.162,0.1,0.219,0.219,0.771,0,0,-1.3,1.6
ENSMUSG00000031651,TRIML1,tripartite motif family-like 1,cellular_component|,multicellular organismal development|,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.2,0.245,0.2,0.211,0.211,0.774,0,0,-0.9,1.9
ENSMUSG00000025538,SUMF2,sulfatase modifying factor 2,endoplasmic reticulum|,biological_process|,protein binding|protein homodimerization activity|metal ion binding|,10,-0.1,0.042,10,-0.4,0.457,-0.1,0.211,-0.211,0.774,0,0,-1.6,1.3
ENSMUSG00000089715,CBX6,chromobox 6,heterochromatin|nucleus|nucleus|PcG protein complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|",single-stranded RNA binding|,10,0.4,1.29,10,0,0,0.1,0.209,0.209,0.775,0,0,-0.8,2
ENSMUSG00000028101,PIAS3,protein inhibitor of activated STAT 3,nucleus|nucleus|cytoplasm|dendrite|synapse|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of gene expression|protein sumoylation|positive regulation of protein sumoylation|positive regulation of membrane potential|","nucleic acid binding|protein binding|protein C-terminus binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|potassium channel regulator activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|enzyme binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein N-terminus binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,1.2,0.645,10,0.4,0.856,-0.1,0.207,-0.207,0.776,0,0,-0.9,2
ENSMUSG00000040997,ABHD4,abhydrolase domain containing 4,None,lipid metabolic process|lipid catabolic process|,"phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.1,0.207,10,0.2,0.383,0.1,0.206,0.206,0.776,0,0,-1.2,1.6
ENSMUSG00000010609,PSEN2,presenilin 2,kinetochore|nucleus|nuclear inner membrane|mitochondrial inner membrane|lysosomal membrane|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|centrosome|cytosol|integral component of plasma membrane|integral component of plasma membrane|cell cortex|cell surface|membrane|membrane|integral component of membrane|apical plasma membrane|Z disc|axon|growth cone|neuromuscular junction|ciliary rootlet|ciliary basal body|neuronal cell body|dendritic shaft|protein complex|membrane raft|perinuclear region of cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|cell fate specification|somitogenesis|positive regulation of receptor recycling|negative regulation of protein phosphorylation|hair follicle development|hematopoietic progenitor cell differentiation|T cell activation involved in immune response|myeloid leukocyte differentiation|proteolysis|membrane protein ectodomain proteolysis|membrane protein ectodomain proteolysis|calcium ion transport|negative regulation of epidermal growth factor-activated receptor activity|regulation of epidermal growth factor-activated receptor activity|Notch signaling pathway|Notch receptor processing|learning or memory|memory|embryo development|protein transport|protein processing|protein processing|dorsal/ventral neural tube patterning|embryonic limb morphogenesis|forebrain development|negative regulation of protein complex assembly|negative regulation of protein binding|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|endoplasmic reticulum calcium ion homeostasis|intracellular signal transduction|locomotion|anagen|amyloid precursor protein catabolic process|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of catalytic activity|regulation of protein binding|skin morphogenesis|cellular protein metabolic process|regulation of synaptic plasticity|lung alveolus development|thymus development|brain morphogenesis|beta-amyloid metabolic process|beta-amyloid metabolic process|positive regulation of coagulation|T cell receptor signaling pathway|negative regulation of ubiquitin-protein transferase activity|protein maturation|cardiac muscle contraction|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of apoptotic signaling pathway|,"endopeptidase activity|endopeptidase activity|aspartic-type endopeptidase activity|protein binding|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|",10,0.1,0.273,10,0,0,0.1,0.206,0.206,0.776,0,0,-1.1,1.8
ENSMUSG00000055385,RNF212,ring finger protein 212,synaptonemal complex|nucleus|chromosome|,meiotic gene conversion|meiotic nuclear division|reciprocal meiotic recombination|protein sumoylation|protein sumoylation|chiasma assembly|,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|SUMO ligase activity|SUMO ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.151,10,-0.1,0.074,-0.1,0.205,-0.205,0.777,0,0,-1.7,1.4
ENSMUSG00000056185,SNX32,sorting nexin 32,endosome|,transport|intracellular protein transport|protein transport|,phosphatidylinositol binding|,9,0.3,0.624,9,-0.3,0.76,0.1,0.204,0.204,0.777,0,0,-1.4,1.6
ENSMUSG00000074793,HSPA12B,heat shock protein 12B,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0.2,0.52,0.2,0.204,0.204,0.777,0,0,-0.8,1.9
ENSMUSG00000036833,PNPLA7,patatin-like phospholipase domain containing 7,nucleus|mitochondrion|lysosome|endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,lipid metabolic process|metabolic process|,"phospholipase activity|lysophospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|carboxylic ester hydrolase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.2,0.65,10,0,0,0.1,0.199,0.199,0.779,0,0,-1.7,1.3
ENSMUSG00000033510,OTUD7A,OTU domain containing 7A,cellular_component|nucleus|cytoplasm|,proteolysis|protein K11-linked deubiquitination|,DNA binding|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.00664,10,-0.2,0.643,-0.1,0.198,-0.198,0.779,0,0,-1.4,1.5
ENSMUSG00000042828,TRIM72,tripartite motif-containing 72,intracellular|cell|plasma membrane|membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle|sarcolemma|,plasma membrane repair|muscle system process|transport|exocytosis|membrane budding|muscle organ development|protein homooligomerization|,phosphatidylserine binding|protein binding|zinc ion binding|metal ion binding|,10,-0.3,0.621,10,0,0,-0.1,0.198,-0.198,0.779,0,0,-1.6,1.3
ENSMUSG00000024184,PDIA2,protein disulfide isomerase associated 2,endoplasmic reticulum|,protein folding|protein folding|response to endoplasmic reticulum stress|cell redox homeostasis|regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,protein disulfide isomerase activity|protein disulfide isomerase activity|steroid binding|lipid binding|isomerase activity|peptidyl-proline 4-dioxygenase activity|,10,0,0,10,0.2,0.472,0.1,0.196,0.196,0.78,0,0,-1.7,1.2
ENSMUSG00000090115,USP49,ubiquitin specific peptidase 49,nucleus|,"mRNA splicing, via spliceosome|mRNA processing|proteolysis|ubiquitin-dependent protein catabolic process|RNA splicing|chromatin modification|protein deubiquitination|histone H2B conserved C-terminal lysine deubiquitination|",cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|histone binding|metal ion binding|,10,0.1,0.0448,10,0.1,0.167,0.1,0.194,0.194,0.781,0,0,-1.4,1.5
ENSMUSG00000035621,MIDN,midnolin,nucleus|nucleolus|cytosol|,negative regulation of glucokinase activity|negative regulation of insulin secretion|,kinase binding|,10,0,0,10,-1.3,2.74,-0.3,0.193,-0.193,0.782,0,0,-3,0.6
ENSMUSG00000034707,GNS,glucosamine (N-acetyl)-6-sulfatase,lysosome|extracellular vesicular exosome|,metabolic process|glycosaminoglycan metabolic process|,catalytic activity|glycosaminoglycan binding|N-acetylglucosamine-6-sulfatase activity|sulfuric ester hydrolase activity|hydrolase activity|sulfate binding|metal ion binding|,10,-0.1,0.0932,10,-0.1,0.118,-0.1,0.193,-0.193,0.782,0,0,-1.8,1.1
ENSMUSG00000032267,USP28,ubiquitin specific peptidase 28,nucleus|nucleoplasm|protein complex|,DNA damage checkpoint|DNA repair|proteolysis|ubiquitin-dependent protein catabolic process|cellular response to DNA damage stimulus|cell proliferation|response to ionizing radiation|protein deubiquitination|cellular response to UV|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|,ubiquitin thiolesterase activity|ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|ubiquitinyl hydrolase activity|,10,0.2,0.644,10,-0.9,0.0528,0.1,0.192,0.192,0.782,0,0,-1.9,1.1
ENSMUSG00000034552,ZSWIM2,zinc finger SWIM-type containing 2,cellular_component|,protein polyubiquitination|apoptotic process|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein self-association|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.097,10,-0.1,0.112,-0.1,0.19,-0.19,0.783,0,0,-1.5,1.4
ENSMUSG00000055652,KLHL25,kelch-like 25,cytoplasm|Cul3-RING ubiquitin ligase complex|,regulation of translation|regulation of translational initiation|protein ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,molecular_function|,10,0.1,0.243,10,0,0,0.1,0.19,0.19,0.783,0,0,-1.2,1.7
ENSMUSG00000036596,CPZ,carboxypeptidase Z,extracellular region|proteinaceous extracellular matrix|extracellular vesicular exosome|,proteolysis|Wnt signaling pathway|protein processing|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,1.2,2.41,10,-0.1,0.0573,0.1,0.19,0.19,0.783,0,0,-0.6,2
ENSMUSG00000054033,ADAM39,a disintegrin and metallopeptidase domain 39,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.64,10,0.4,1.53,-0.2,0.189,-0.189,0.783,0,0,-1.4,1.4
ENSMUSG00000019732,CALR3,calreticulin 3,endoplasmic reticulum|,protein folding|spermatogenesis|cell differentiation|,calcium ion binding|protein binding|protein binding involved in protein folding|unfolded protein binding|,10,0,0,10,-0.2,0.411,-0.1,0.185,-0.185,0.785,0,0,-1.8,1.1
ENSMUSG00000042350,AREL1,apoptosis resistant E3 ubiquitin protein ligase 1,nucleus|cytoplasm|cytosol|,apoptotic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.3,0.378,10,0,0,0.1,0.185,0.185,0.785,0,0,-0.9,1.9
ENSMUSG00000058446,ZNRF2,zinc and ring finger 2,cytoplasm|lysosome|endosome|plasma membrane|membrane|cell junction|cytoplasmic vesicle membrane|protein complex|synapse|,protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.0165,10,-0.1,0.183,-0.1,0.182,-0.182,0.786,0,0,-1.7,1.1
ENSMUSG00000029228,LNX1,ligand of numb-protein X 1,cytoplasm|,ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein homooligomerization|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|PDZ domain binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.641,10,0,0,-0.1,0.181,-0.181,0.787,0,0,-1.7,1.2
ENSMUSG00000033530,TTC7B,tetratricopeptide repeat domain 7B,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.26,10,0.1,0.261,-0.1,0.18,-0.18,0.787,0,0,-1.6,1.2
ENSMUSG00000029369,AFM,afamin,extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,transport|vitamin transport|,vitamin E binding|,10,0.3,0.387,10,0.1,0.0764,0.1,0.179,0.179,0.787,0,0,-1.1,1.7
ENSMUSG00000029268,UGT2A1,"UDP glucuronosyltransferase 2 family, polypeptide A1",cellular_component|,sensory perception of smell|metabolic process|cellular glucuronidation|,glucuronosyltransferase activity|glucuronosyltransferase activity|,10,0.3,0.483,10,-0.1,0.00392,0.1,0.178,0.178,0.788,0,0,-1.4,1.5
ENSMUSG00000046971,PLA2G4F,"phospholipase A2, group IVF",cytoplasm|lysosome|cytosol|membrane|vesicle|ruffle membrane|,prostaglandin biosynthetic process|lipid metabolic process|metabolic process|phospholipid catabolic process|fatty acid transport|lipid catabolic process|arachidonic acid secretion|cellular response to antibiotic|cellular response to organic cyclic compound|,phospholipase activity|lysophospholipase activity|phospholipase A2 activity|hydrolase activity|metal ion binding|calcium-dependent phospholipase A2 activity|,10,0.5,0.901,10,0,0,0.2,0.174,0.174,0.789,0,0,-0.5,2
ENSMUSG00000034460,SIX4,sine oculis-related homeobox 4,nucleus|nucleus|cytoplasm|,"regulation of transcription, DNA-templated|multicellular organismal development|skeletal muscle tissue development|regulation of synaptic growth at neuromuscular junction|regulation of gene expression|regulation of protein localization|inner ear morphogenesis|negative regulation of neuron apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|thymus development|generation of neurons|embryonic cranial skeleton morphogenesis|embryonic skeletal system morphogenesis|anatomical structure development|myoblast migration|metanephric mesenchyme development|regulation of branch elongation involved in ureteric bud branching|positive regulation of ureteric bud formation|positive regulation of branching involved in ureteric bud morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0.2,0.462,10,0,0,0.1,0.173,0.173,0.79,0,0,-1.5,1.5
ENSMUSG00000003123,LIPE,"lipase, hormone sensitive",extracellular space|nucleus|cytoplasm|cytoplasm|mitochondrion|lipid particle|cytosol|plasma membrane|caveola|membrane|,transcription initiation from RNA polymerase I promoter|termination of RNA polymerase I transcription|lipid metabolic process|metabolic process|steroid metabolic process|cholesterol metabolic process|lipid catabolic process|triglyceride catabolic process|triglyceride catabolic process|triglyceride catabolic process|long-chain fatty acid catabolic process|diacylglycerol catabolic process|diacylglycerol catabolic process|,"triglyceride lipase activity|protein binding|lipase activity|hydrolase activity|hydrolase activity, acting on ester bonds|protein kinase binding|hormone-sensitive lipase activity|rRNA primary transcript binding|acylglycerol lipase activity|",10,-0.2,1.06,10,0.9,0.136,-0.2,0.17,-0.17,0.791,0,0,-1.6,1.7
ENSMUSG00000036955,2510003E04RIK,RIKEN cDNA 2510003E04 gene,cytoplasm|mitochondrion|cytoskeleton|,mitochondrial transport|multicellular organismal development|nervous system development|cell differentiation|,kinesin binding|,10,-0.8,2.29,10,0.1,0.0722,0.1,0.169,0.169,0.791,0,0,-2,0.9
ENSMUSG00000025738,FBXL16,F-box and leucine-rich repeat protein 16,cytoplasm|,biological_process|,molecular_function|,10,0.1,0.411,10,0,0,0.1,0.167,0.167,0.792,0,0,-1.2,1.7
ENSMUSG00000037005,XPNPEP2,"X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound",extracellular vesicular exosome|,proteolysis|biological_process|,molecular_function|aminopeptidase activity|peptidase activity|hydrolase activity|metal ion binding|,10,-0.2,0.759,10,0.3,1.09,0.2,0.165,0.165,0.793,0,0,-1.1,1.6
ENSMUSG00000069601,ANK3,"ankyrin 3, epithelial",intracellular|cell|cytoplasm|lysosome|cytoskeleton|plasma membrane|tight junction|basal plasma membrane|cell surface|intercalated disc|intercalated disc|spectrin-associated cytoskeleton|membrane|basolateral plasma membrane|lateral plasma membrane|sarcoplasmic reticulum|Z disc|cell junction|T-tubule|axon|dendrite|neuromuscular junction|node of Ranvier|node of Ranvier|paranode region of axon|sarcolemma|cell projection|neuron projection|axon initial segment|axon initial segment|synapse|postsynaptic membrane|,mitotic cytokinesis|plasma membrane organization|signal transduction|axonogenesis|axon guidance|positive regulation of gene expression|positive regulation of cell communication by electrical coupling|positive regulation of sodium ion transport|neuronal action potential|positive regulation of homotypic cell-cell adhesion|Golgi to plasma membrane protein transport|regulation of potassium ion transport|establishment of protein localization|positive regulation of action potential|positive regulation of membrane potential|synapse organization|membrane assembly|protein localization to plasma membrane|protein localization to plasma membrane|protein localization to plasma membrane|maintenance of protein location in plasma membrane|protein targeting to plasma membrane|protein targeting to plasma membrane|positive regulation of protein targeting to membrane|positive regulation of membrane depolarization during cardiac muscle cell action potential|positive regulation of sodium ion transmembrane transporter activity|positive regulation of cation channel activity|,"structural constituent of cytoskeleton|protein binding|cytoskeletal protein binding|spectrin binding|protein binding, bridging|ion channel binding|cadherin binding|",10,0.3,0.216,10,-0.2,0.744,-0.1,0.165,-0.165,0.793,0,0,-1.2,1.6
ENSMUSG00000047446,ARL4A,ADP-ribosylation factor-like 4A,intracellular|nucleus|nucleus|nucleolus|cytoplasm|plasma membrane|membrane|,GTP catabolic process|small GTPase mediated signal transduction|brown fat cell differentiation|,nucleotide binding|GTPase activity|GTP binding|,10,-0.1,0.121,10,-0.1,0.053,-0.1,0.159,-0.159,0.796,0,0,-1.6,1.2
ENSMUSG00000036225,KCTD1,potassium channel tetramerisation domain containing 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|protein homooligomerization|",transcription corepressor activity|transcription factor binding|,10,0.1,0.0816,10,0.1,0.0907,0.1,0.157,0.157,0.797,0,0,-1.6,1.4
ENSMUSG00000024944,ARL2,ADP-ribosylation factor-like 2,intracellular|nucleus|cytoplasm|mitochondrion|mitochondrial intermembrane space|Golgi apparatus|centrosome|cytosol|cytoskeleton|extracellular vesicular exosome|,GTP catabolic process|cell cycle|small GTPase mediated signal transduction|acetylcholine transport|regulation of microtubule polymerization|positive regulation of microtubule polymerization|negative regulation of GTPase activity|centrosome organization|maintenance of protein location in nucleus|,nucleotide binding|GTPase activity|protein binding|GTP binding|GTP binding|GDP binding|,6,0.3,0.949,6,0,0,0.1,0.157,0.157,0.797,0,0,-1.5,1.8
ENSMUSG00000026388,3110009E18RIK,RIKEN cDNA 3110009E18 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.371,10,0,0,-0.1,0.156,-0.156,0.797,0,0,-1.8,1.1
ENSMUSG00000026198,ABCB6,"ATP-binding cassette, sub-family B (MDR/TAP), member 6",mitochondrion|mitochondrion|mitochondrial envelope|mitochondrial outer membrane|endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|extracellular vesicular exosome|,ATP catabolic process|porphyrin-containing compound biosynthetic process|transport|brain development|heme transport|skin development|transmembrane transport|transmembrane transport|,"nucleotide binding|ATP binding|heme-transporting ATPase activity|efflux transmembrane transporter activity|ATPase activity|heme binding|ATPase activity, coupled to transmembrane movement of substances|",10,0.1,0.053,10,0.1,0.115,0.1,0.153,0.153,0.798,0,0,-2,1.1
ENSMUSG00000055891,UBL4B,ubiquitin-like 4B,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,-0.3,0.951,10,0.3,1.17,-0.1,0.153,-0.153,0.798,0,0,-1.5,1.6
ENSMUSG00000041827,OASL1,2'-5' oligoadenylate synthetase-like 1,nucleus|nucleolus|cytoplasm|membrane|,immune system process|immune response|response to virus|negative regulation of viral genome replication|innate immune response|defense response to virus|,DNA binding|RNA binding|double-stranded RNA binding|double-stranded RNA binding|ATP binding|transferase activity|poly(A) RNA binding|,10,0.3,0.698,10,0,0,0.1,0.152,0.152,0.799,0,0,-1.1,1.7
ENSMUSG00000026644,ACBD7,acyl-Coenzyme A binding domain containing 7,cellular_component|,biological_process|,fatty-acyl-CoA binding|molecular_function|lipid binding|,10,-0.3,0.379,10,0.2,0.481,0.1,0.151,0.151,0.799,0,0,-1.5,1.4
ENSMUSG00000022837,IQCB1,IQ calmodulin-binding motif containing 1,photoreceptor outer segment|nucleus|cytoplasm|centrosome|cytoskeleton|microtubule cytoskeleton|photoreceptor connecting cilium|photoreceptor connecting cilium|intercellular bridge|,cilium assembly|photoreceptor cell maintenance|photoreceptor cell maintenance|maintenance of organ identity|maintenance of organ identity|,protein binding|calmodulin binding|calmodulin binding|enzyme binding|,10,1.1,0.914,10,0.2,0.491,0.1,0.15,0.15,0.799,0,0,-0.7,2
ENSMUSG00000000197,NALCN,"sodium leak channel, non-selective",plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|regulation of ion transmembrane transport|transmembrane transport|calcium ion import|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|cation channel activity|sodium channel activity|,10,0.1,0.215,10,0,0,0.1,0.149,0.149,0.8,0,0,-0.8,2
ENSMUSG00000042572,UBE2Q1,ubiquitin-conjugating enzyme E2Q (putative) 1,cell|,suckling behavior|embryo implantation|mating behavior|fertilization|reproductive system development|prolactin secretion|,nucleotide binding|molecular_function|ATP binding|transferase activity|ligase activity|acid-amino acid ligase activity|,10,0.3,1.48,10,-0.3,1.45,-0.1,0.148,-0.148,0.8,0,0,-1.6,1.3
ENSMUSG00000031610,SCRG1,scrapie responsive gene 1,extracellular region|,None,None,10,0,0,10,-0.8,0.625,-0.1,0.147,-0.147,0.801,0,0,-2,1
ENSMUSG00000028673,FUCA1,"fucosidase, alpha-L- 1, tissue",lysosome|lysosome|extracellular vesicular exosome|,carbohydrate metabolic process|fucose metabolic process|metabolic process|glycoside catabolic process|,"alpha-L-fucosidase activity|alpha-L-fucosidase activity|fucosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|fucose binding|",10,-0.5,0.84,10,0,0,0.1,0.146,0.146,0.801,0,0,-1.6,1.3
ENSMUSG00000024910,CTSW,cathepsin W,membrane|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.4,1.1,10,-0.3,0.298,0.2,0.144,0.144,0.802,0,0,-1.5,1.4
ENSMUSG00000040811,EML2,echinoderm microtubule associated protein like 2,cytoplasm|cytoskeleton|microtubule|mitotic spindle|,regulation of microtubule nucleation|negative regulation of microtubule polymerization|,receptor binding|microtubule binding|protein C-terminus binding|tubulin binding|,10,-0.2,0.429,10,0.3,0.558,0.1,0.143,0.143,0.802,0,0,-1.2,1.7
ENSMUSG00000045594,GLB1,"galactosidase, beta 1",cytoplasm|lysosome|Golgi apparatus|extracellular vesicular exosome|,carbohydrate metabolic process|metabolic process|galactose catabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-galactosidase activity|beta-galactosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|galactoside binding|",10,0.3,0.707,10,0,0,0.2,0.142,0.142,0.803,0,0,-0.6,2
ENSMUSG00000041268,DMXL2,Dmx-like 2,extracellular space|synaptic vesicle|membrane|cell junction|cytoplasmic vesicle|synapse|,biological_process|,Rab GTPase binding|,10,-0.2,0.636,10,0,0,-0.1,0.141,-0.141,0.803,0,0,-1.7,1.1
ENSMUSG00000031376,ATP2B3,"ATPase, Ca++ transporting, plasma membrane 3",Golgi apparatus|plasma membrane|membrane|integral component of membrane|membrane raft|,None,nucleotide binding|ATP binding|hydrolase activity|PDZ domain binding|,10,-0.1,0.541,10,0,0,-0.1,0.14,-0.14,0.804,0,0,-1.1,2
ENSMUSG00000040017,SAA4,serum amyloid A 4,extracellular region|high-density lipoprotein particle|,acute-phase response|,None,10,0.2,0.613,10,-0.2,0.689,-0.1,0.14,-0.14,0.804,0,0,-1.4,1.4
ENSMUSG00000050108,BPIFC,BPI fold containing family C,cellular_component|extracellular region|,biological_process|,lipid binding|,10,0.3,0.804,10,-0.3,0.451,0.1,0.138,0.138,0.805,0,0,-1,1.9
ENSMUSG00000052917,SENP7,SUMO1/sentrin specific peptidase 7,intracellular|nucleus|,proteolysis|biological_process|,molecular_function|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,-0.3,0.935,10,0.1,0.116,0.1,0.137,0.137,0.805,0,0,-1.5,1.3
ENSMUSG00000020696,RFFL,ring finger and FYVE like domain containing protein,tumor necrosis factor receptor superfamily complex|cytoplasm|endosome|plasma membrane|endosome membrane|membrane|membrane|cytoplasmic membrane-bounded vesicle|,ubiquitin-dependent protein catabolic process|intracellular protein transport|apoptotic process|regulation of fibroblast migration|negative regulation of tumor necrosis factor-mediated signaling pathway|proteasome-mediated ubiquitin-dependent protein catabolic process|protein K48-linked ubiquitination|negative regulation of signal transduction by p53 class mediator|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis|,"protease binding|p53 binding|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein kinase binding|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.6,0.755,-0.4,0.137,-0.137,0.805,0,0,-1.9,0.9
ENSMUSG00000056019,ZFP709,zinc finger protein 709,plasma membrane|,cellular response to heat|cellular response to lipopolysaccharide|,metal ion binding|,10,0,0,10,0.1,0.149,0.1,0.134,0.134,0.807,0,0,-1.8,1.1
ENSMUSG00000071192,WFIKKN1,"WAP, FS, Ig, KU, and NTR-containing protein 1",extracellular region|,skeletal system development|negative regulation of peptidase activity|negative regulation of protein binding|negative regulation of DNA binding|negative regulation of proteolysis|muscle fiber development|palate development|,enzyme inhibitor activity|serine-type endopeptidase inhibitor activity|protein binding|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.2,0.596,10,0.1,0.111,-0.1,0.134,-0.134,0.807,0,0,-1.4,1.5
ENSMUSG00000041926,RNPEP,arginyl aminopeptidase (aminopeptidase B),extracellular region|extracellular space|Golgi apparatus|plasma membrane|external side of plasma membrane|secretory granule|neuron projection|extracellular vesicular exosome|,proteolysis|leukotriene biosynthetic process|negative regulation of blood pressure|,aminopeptidase activity|copper ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|peptide binding|metal ion binding|cobalt ion binding|metalloaminopeptidase activity|,10,-0.1,0.468,10,0,0,-0.1,0.133,-0.133,0.807,0,0,-1.3,1.7
ENSMUSG00000029440,PSMD9,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 9","proteasome complex|nucleus|nucleus|proteasome regulatory particle, base subcomplex|","positive regulation of insulin secretion|positive regulation of insulin secretion|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|negative regulation of insulin secretion|negative regulation of insulin secretion|proteasome regulatory particle assembly|type B pancreatic cell apoptotic process|",transcription coactivator activity|transcription coactivator activity|protein C-terminus binding|bHLH transcription factor binding|bHLH transcription factor binding|,10,0.2,0.406,10,-0.1,0.12,0.1,0.133,0.133,0.807,0,0,-1.1,1.7
ENSMUSG00000052616,CCDC79,coiled-coil domain containing 79,"chromosome, telomeric region|chromosome|",meiotic nuclear division|synapsis|meiotic telomere clustering|,DNA binding|chromatin binding|protein binding|,10,0,0,10,0.2,0.579,0.1,0.132,0.132,0.807,0,0,-1.3,1.6
ENSMUSG00000035759,BBS10,Bardet-Biedl syndrome 10 (human),cellular_component|cell projection|,retina homeostasis|nonmotile primary cilium assembly|regulation of protein complex assembly|cellular protein metabolic process|photoreceptor cell maintenance|chaperone-mediated protein complex assembly|,nucleotide binding|RNA polymerase II repressing transcription factor binding|ATP binding|,10,0.2,0.657,10,-0.1,0.206,-0.1,0.127,-0.127,0.81,0,0,-1.2,1.7
ENSMUSG00000032649,COLGALT2,collagen beta(1-O)galactosyltransferase 2,cellular_component|endoplasmic reticulum|,biological_process|lipopolysaccharide biosynthetic process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|procollagen galactosyltransferase activity|",10,0.2,0.544,10,0,0,0.2,0.127,0.127,0.81,0,0,-1.1,1.8
ENSMUSG00000039952,DAG1,dystroglycan 1,extracellular region|basement membrane|basement membrane|extracellular space|nucleus|nucleoplasm|cytoplasm|cytoskeleton|plasma membrane|plasma membrane|cell-cell junction|cell-cell adherens junction|focal adhesion|focal adhesion|cell outer membrane|dystrophin-associated glycoprotein complex|dystroglycan complex|membrane|integral component of membrane|basolateral plasma membrane|lamellipodium|cell junction|filopodium|node of Ranvier|sarcolemma|sarcolemma|costamere|membrane raft|synapse|postsynaptic membrane|extracellular vesicular exosome|contractile ring|,morphogenesis of an epithelial sheet|membrane protein ectodomain proteolysis|NLS-bearing protein import into nucleus|cytoskeletal anchoring at plasma membrane|Schwann cell development|viral process|calcium-dependent cell-matrix adhesion|modulation by virus of host morphology or physiology|nerve maturation|myelination in peripheral nervous system|negative regulation of cell migration|microtubule anchoring|negative regulation of MAPK cascade|negative regulation of protein kinase B signaling|epithelial tube branching involved in lung morphogenesis|branching involved in salivary gland morphogenesis|commissural neuron axon guidance|basement membrane organization|,dystroglycan binding|actin binding|calcium ion binding|protein binding|structural constituent of muscle|tubulin binding|vinculin binding|protein complex binding|SH2 domain binding|alpha-actinin binding|,10,0,0,10,0.1,0.303,0.1,0.126,0.126,0.81,0,0,-1.2,1.8
ENSMUSG00000047586,NCCRP1,non-specific cytotoxic cell receptor protein 1 homolog (zebrafish),cytoplasm|extracellular vesicular exosome|,positive regulation of cell proliferation|,molecular_function|,10,1,0.23,10,-0.1,0.36,-0.1,0.125,-0.125,0.811,0,0,-1,2
ENSMUSG00000045019,ACER1,alkaline ceramidase 1,endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|ceramide metabolic process|response to alkalinity|regulation of lipid metabolic process|sphingolipid biosynthetic process|cell differentiation|sphingosine biosynthetic process|ceramide catabolic process|cellular response to calcium ion|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|ceramidase activity|ceramidase activity|dihydroceramidase activity|",10,0,0,10,0.2,0.892,0.1,0.124,0.124,0.811,0,0,-1,1.8
ENSMUSG00000022216,PSME1,"proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)",proteasome complex|proteasome activator complex|extracellular vesicular exosome|,positive regulation of endopeptidase activity|antigen processing and presentation of exogenous antigen|,protein binding|endopeptidase activator activity|,10,0.2,0.32,10,-0.3,1.34,-0.1,0.124,-0.124,0.811,0,0,-1.6,1.2
ENSMUSG00000031149,PRAF2,PRA1 domain family 2,cellular_component|endosome|membrane|integral component of membrane|,transport|biological_process|protein transport|,molecular_function|,10,0,0,10,0.1,0.242,0.1,0.122,0.122,0.812,0,0,-1,1.8
ENSMUSG00000020566,ATP6V1C2,"ATPase, H+ transporting, lysosomal V1 subunit C2","lysosomal membrane|proton-transporting V-type ATPase, V1 domain|extracellular vesicular exosome|",ATP catabolic process|transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|positive regulation of Wnt signaling pathway|hydrogen ion transmembrane transport|,"hydrogen-exporting ATPase activity, phosphorylative mechanism|hydrogen ion transmembrane transporter activity|protein dimerization activity|",10,0.1,0.346,10,0,0,0.1,0.121,0.121,0.812,0,0,-0.9,2
ENSMUSG00000070999,CCIN,calicin,nucleus|cytoplasm|cytoskeleton|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,0,0,10,-0.7,1.55,-0.1,0.12,-0.12,0.813,0,0,-1.8,1.1
ENSMUSG00000070527,MKRN3,"makorin, ring finger protein, 3",None,None,"zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.333,10,-0.1,0.195,-0.1,0.12,-0.12,0.813,0,0,-1.5,1.3
ENSMUSG00000032080,APOA4,apolipoprotein A-IV,extracellular region|extracellular space|extracellular space|cell surface|very-low-density lipoprotein particle|high-density lipoprotein particle|chylomicron|extracellular vesicular exosome|blood microparticle|,innate immune response in mucosa|innate immune response in mucosa|transport|lipid transport|response to lipid hydroperoxide|leukocyte cell-cell adhesion|cholesterol metabolic process|positive regulation of cholesterol esterification|positive regulation of triglyceride catabolic process|removal of superoxide radicals|regulation of intestinal cholesterol absorption|regulation of cholesterol transport|cholesterol efflux|phospholipid efflux|very-low-density lipoprotein particle remodeling|negative regulation of plasma lipoprotein particle oxidation|lipoprotein metabolic process|cholesterol homeostasis|hydrogen peroxide catabolic process|reverse cholesterol transport|multicellular organismal lipid catabolic process|positive regulation of fatty acid biosynthetic process|phosphatidylcholine metabolic process|positive regulation of lipoprotein lipase activity|lipid homeostasis|protein-lipid complex assembly|,copper ion binding|lipid binding|antioxidant activity|cholesterol transporter activity|phosphatidylcholine binding|protein homodimerization activity|phosphatidylcholine-sterol O-acyltransferase activator activity|,10,0,0,9,0.1,0.213,0.1,0.118,0.118,0.814,0,0,-2,1
ENSMUSG00000028550,ATG4C,"autophagy related 4C, cysteine peptidase",extracellular region|cytoplasm|,autophagic vacuole assembly|proteolysis|proteolysis|transport|autophagy|autophagy|protein transport|,cysteine-type endopeptidase activity|cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,-0.2,0.519,10,0,0,-0.1,0.117,-0.117,0.814,0,0,-1.8,1.1
ENSMUSG00000022347,A1BG,alpha-1-B glycoprotein,extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,biological_process|,molecular_function|,10,0,0,10,0.2,0.41,0.1,0.117,0.117,0.814,0,0,-1,1.9
ENSMUSG00000078441,SCAMP4,secretory carrier membrane protein 4,membrane|integral component of membrane|transport vesicle|,transport|biological_process|protein transport|,molecular_function|,10,-0.4,1.74,10,0.1,0.0757,-0.1,0.115,-0.115,0.815,0,0,-1.8,1
ENSMUSG00000027006,DNAJC10,"DnaJ (Hsp40) homolog, subfamily C, member 10",endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum lumen|membrane|endoplasmic reticulum chaperone complex|,negative regulation of protein phosphorylation|ER-associated ubiquitin-dependent protein catabolic process|ER-associated ubiquitin-dependent protein catabolic process|positive regulation of ATPase activity|protein folding in endoplasmic reticulum|response to endoplasmic reticulum stress|cell redox homeostasis|oxidation-reduction process|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,"ATPase activator activity|protein binding|peptide-methionine (S)-S-oxide reductase activity|protein disulfide oxidoreductase activity|protein disulfide oxidoreductase activity|disulfide oxidoreductase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor|Hsp70 protein binding|peptide-methionine (R)-S-oxide reductase activity|chaperone binding|chaperone binding|ATPase binding|ATPase binding|misfolded protein binding|methionine-R-sulfoxide reductase activity|",9,0,0,9,-0.1,0.363,-0.1,0.114,-0.114,0.815,0,0,-1.3,1.8
ENSMUSG00000020986,SEC23A,SEC23A (S. cerevisiae),Golgi membrane|intracellular|cell|endoplasmic reticulum|Golgi apparatus|membrane|COPII vesicle coat|ER to Golgi transport vesicle|perinuclear region of cytoplasm|,transport|intracellular protein transport|ER to Golgi vesicle-mediated transport|protein transport|vesicle-mediated transport|,protein binding|zinc ion binding|,10,0,0,10,1.1,1.06,0.1,0.112,0.112,0.816,0,0,-0.8,2
ENSMUSG00000070923,KLHL9,kelch-like 9,midbody|Cul3-RING ubiquitin ligase complex|,cytokinesis|cell cycle|mitotic nuclear division|protein ubiquitination|cell division|,ubiquitin-protein transferase activity|,9,1,1.17,9,-0.5,0.529,0.3,0.111,0.111,0.817,0,0,-1.1,2
ENSMUSG00000040502,9-Mar,membrane-associated ring finger (C3HC4) 9,lysosome|Golgi apparatus|Golgi stack|trans-Golgi network|membrane|integral component of membrane|,biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.066,10,-0.9,1.26,0.1,0.111,0.111,0.817,0,0,-2,0.8
ENSMUSG00000002546,GOLGA2,"golgi autoantigen, golgin subfamily a, 2",Golgi cis cisterna|cytoplasm|Golgi apparatus|Golgi apparatus|cis-Golgi network|cis-Golgi network|membrane|neuronal cell body|protein complex|Golgi apparatus part|,positive regulation of axonogenesis|Golgi localization|,protein binding|protein complex binding|,10,-0.3,0.989,10,0,0,-0.1,0.107,-0.107,0.818,0,0,-1.8,1.1
ENSMUSG00000030283,ST8SIA1,"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|lipid metabolic process|sphingolipid metabolic process|positive regulation of cell proliferation|cellular response to heat|sialylation|,"alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,10,0.1,0.45,0.1,0.107,0.107,0.818,0,0,-1.2,1.7
ENSMUSG00000014164,KLHL3,kelch-like 3,cytoplasm|cytosol|cytoskeleton|Cul3-RING ubiquitin ligase complex|,protein ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|ion homeostasis|renal sodium ion absorption|protein K48-linked ubiquitination|distal tubule morphogenesis|,molecular_function|actin binding|catalytic activity|,10,-0.1,0.187,10,0.2,0.172,-0.1,0.106,-0.106,0.819,0,0,-1.5,1.4
ENSMUSG00000021484,LMAN2,"lectin, mannose-binding 2",extracellular space|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|integral component of plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,"transport|retrograde vesicle-mediated transport, Golgi to ER|protein transport|positive regulation of phagocytosis|",glycoprotein binding|mannose binding|carbohydrate binding|heat shock protein binding|metal ion binding|,10,-0.1,0.0859,10,-0.2,0.0376,-0.2,0.104,-0.104,0.82,0,0,-2,0.9
ENSMUSG00000033453,ADAMTS15,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15",extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,-0.2,0.614,9,0.1,0.107,0.1,0.103,0.103,0.82,0,0,-1.4,1.5
ENSMUSG00000039405,PRSS23,"protease, serine 23",extracellular region|nucleus|extracellular vesicular exosome|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.1,0.128,-0.1,0.102,-0.102,0.82,0,0,-1.6,1.4
ENSMUSG00000035566,PCDH17,protocadherin 17,plasma membrane|membrane|integral component of membrane|,cell adhesion|,None,10,0.2,0.206,10,-0.2,0.524,-0.1,0.102,-0.102,0.82,0,0,-1.4,1.5
ENSMUSG00000037260,HGSNAT,heparan-alpha-glucosaminide N-acetyltransferase,lysosome|lysosomal membrane|membrane|integral component of membrane|,lysosomal transport|protein oligomerization|,"heparan-alpha-glucosaminide N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.2,0.491,10,0.5,0.321,-0.1,0.102,-0.102,0.82,0,0,-1.3,1.7
ENSMUSG00000026608,KCTD3,potassium channel tetramerisation domain containing 3,cellular_component|,biological_process|protein homooligomerization|,molecular_function|,10,0,0,10,-0.2,0.269,-0.1,0.101,-0.101,0.821,0,0,-1.3,1.6
ENSMUSG00000033931,RBM34,RNA binding motif protein 34,nucleus|nucleolus|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-1.2,0.633,10,0.1,0.0343,-0.1,0.1,-0.1,0.821,0,0,-2,0.9
ENSMUSG00000032096,ARCN1,archain 1,intracellular|cell|cytoplasm|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|membrane|membrane|COPI vesicle coat|clathrin adaptor complex|COPI-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|,"transport|intracellular protein transport|retrograde vesicle-mediated transport, Golgi to ER|adult locomotory behavior|protein transport|vesicle-mediated transport|cerebellar Purkinje cell layer maturation|pigmentation|Golgi vesicle transport|",poly(A) RNA binding|,10,0.2,0.48,8,-1,0.999,0.1,0.0997,0.0997,0.821,0,0,-2,0.9
ENSMUSG00000038074,FKBP14,FK506 binding protein 14,endoplasmic reticulum|endoplasmic reticulum membrane|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|calcium ion binding|FK506 binding|isomerase activity|metal ion binding|,10,-0.2,0.523,10,0,0,0.1,0.0987,0.0987,0.822,0,0,-1.4,1.4
ENSMUSG00000036218,PDZRN4,PDZ domain containing RING finger 4,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.308,10,0,0,0.1,0.0984,0.0984,0.822,0,0,-1.4,1.5
ENSMUSG00000062929,CFL2,"cofilin 2, muscle",extracellular space|intracellular|nucleus|cytoplasm|cytoskeleton|actin cytoskeleton|I band|,actin filament organization|actin filament depolymerization|positive regulation of actin filament depolymerization|sarcomere organization|muscle cell cellular homeostasis|,molecular_function|actin binding|,9,0,0,9,-0.2,0.258,-0.2,0.0978,-0.0978,0.822,0,0,-2,0.8
ENSMUSG00000004415,COL26A1,"collagen, type XXVI, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|endoplasmic reticulum|Golgi apparatus|,positive regulation of cell-substrate adhesion|,protein binding|,10,0,0,10,0.4,0.282,0.1,0.0977,0.0977,0.822,0,0,-1,1.8
ENSMUSG00000037062,SH3GLB1,SH3-domain GRB2-like B1 (endophilin),cytoplasm|mitochondrion|mitochondrial envelope|mitochondrial outer membrane|endoplasmic reticulum|Golgi apparatus|cytosol|membrane|protein complex|extracellular vesicular exosome|,phosphatidic acid biosynthetic process|apoptotic process|phospholipid biosynthetic process|positive regulation of protein oligomerization|'de novo' posttranslational protein folding|protein oligomerization|positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|,fatty acid binding|protein binding|lipid binding|lysophosphatidic acid acyltransferase activity|identical protein binding|protein homodimerization activity|,10,0,0,10,0.2,0.41,0.1,0.0952,0.0952,0.823,0,0,-1.6,1.5
ENSMUSG00000003660,SNRNP200,small nuclear ribonucleoprotein 200 (U5),nucleus|spliceosomal complex|U5 snRNP|membrane|ribonucleoprotein complex|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|osteoblast differentiation|ATP catabolic process|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|ATP-dependent RNA helicase activity|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|identical protein binding|poly(A) RNA binding|,5,-0.1,0.154,5,0.5,1.29,0.4,0.0942,0.0942,0.824,0,0,-1.4,1.9
ENSMUSG00000024457,TRIM26,tripartite motif-containing 26,intracellular|cytoplasm|,innate immune response|negative regulation of viral entry into host cell|positive regulation of sequence-specific DNA binding transcription factor activity|negative regulation of viral release from host cell|,zinc ion binding|metal ion binding|,10,0,0,10,-0.1,0.188,-0.1,0.094,-0.094,0.824,0,0,-1.6,1.3
ENSMUSG00000049107,NTF3,neurotrophin 3,extracellular region|cytoplasmic membrane-bounded vesicle|,activation of MAPK activity|positive regulation of receptor internalization|transmembrane receptor protein tyrosine kinase signaling pathway|neuromuscular synaptic transmission|nervous system development|glial cell fate determination|axon guidance|axon guidance|brain development|peripheral nervous system development|positive regulation of cell proliferation|epidermis development|nerve development|positive regulation of cell migration|activation of protein kinase B activity|activation of Ras GTPase activity|positive regulation of peptidyl-serine phosphorylation|mechanoreceptor differentiation|myelination|regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of glial cell differentiation|positive regulation of transcription from RNA polymerase II promoter|enteric nervous system development|neuron development|generation of neurons|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of peptidyl-tyrosine phosphorylation|regulation of synaptic transmission|positive chemotaxis|induction of positive chemotaxis|smooth muscle cell differentiation|positive regulation of actin cytoskeleton reorganization|,receptor binding|neurotrophin receptor binding|neurotrophin p75 receptor binding|protein binding|growth factor activity|chemoattractant activity|nerve growth factor binding|,10,0,0,10,0.3,0.275,0.1,0.0938,0.0938,0.824,0,0,-1.6,1.4
ENSMUSG00000066621,TECPR1,tectonin beta-propeller repeat containing 1,autophagic vacuole membrane|lysosome|lysosomal membrane|membrane|integral component of membrane|cytoplasmic vesicle|,autophagic vacuole fusion|autophagy|,lipid binding|phosphatidylinositol-3-phosphate binding|,10,-0.1,0.382,10,0,0,-0.1,0.093,-0.093,0.824,0,0,-1.7,1.3
ENSMUSG00000053441,ADAMTS19,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19",extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|integrin-mediated signaling pathway|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.1,0.237,-0.1,0.0924,-0.0924,0.824,0,0,-1.7,1.3
ENSMUSG00000003355,FKBP11,FK506 binding protein 11,endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,protein peptidyl-prolyl isomerization|protein folding|chaperone-mediated protein folding|,peptidyl-prolyl cis-trans isomerase activity|FK506 binding|isomerase activity|,10,0.1,0.101,10,-0.3,1.84,-0.2,0.092,-0.092,0.824,0,0,-1.5,1.3
ENSMUSG00000033792,ATP7A,"ATPase, Cu++ transporting, alpha polypeptide",late endosome|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|trans-Golgi network|trans-Golgi network|plasma membrane|plasma membrane|membrane|membrane|integral component of membrane|basolateral plasma membrane|trans-Golgi network transport vesicle|secretory granule|cytoplasmic vesicle|brush border membrane|neuron projection|neuronal cell body|perinuclear region of cytoplasm|,blood vessel development|release of cytochrome c from mitochondria|blood vessel remodeling|regulation of oxidative phosphorylation|ATP catabolic process|tryptophan metabolic process|tyrosine metabolic process|catecholamine metabolic process|transport|ion transport|cation transport|copper ion transport|copper ion transport|copper ion transport|cellular copper ion homeostasis|cellular copper ion homeostasis|cellular copper ion homeostasis|mitochondrion organization|locomotory behavior|detoxification of copper ion|regulation of gene expression|copper ion import|plasma membrane copper ion transport|peptidyl-lysine modification|removal of superoxide radicals|cerebellar Purkinje cell differentiation|pyramidal neuron development|central nervous system neuron development|metal ion transport|extracellular matrix organization|collagen fibril organization|hair follicle morphogenesis|hindlimb morphogenesis|T-helper cell differentiation|epinephrine metabolic process|norepinephrine metabolic process|dopamine metabolic process|norepinephrine biosynthetic process|serotonin metabolic process|positive regulation of catalytic activity|positive regulation of catalytic activity|pigmentation|negative regulation of neuron apoptotic process|skin development|ATP metabolic process|response to copper ion|elastic fiber assembly|lung alveolus development|negative regulation of metalloenzyme activity|positive regulation of metalloenzyme activity|neuron projection morphogenesis|dendrite morphogenesis|cartilage development|positive regulation of oxidoreductase activity|elastin biosynthetic process|copper ion export|copper ion export|,nucleotide binding|copper-exporting ATPase activity|copper ion transmembrane transporter activity|copper ion transmembrane transporter activity|copper ion binding|protein binding|ATP binding|superoxide dismutase copper chaperone activity|hydrolase activity|cation-transporting ATPase activity|copper-dependent protein binding|metal ion binding|,10,-0.1,0.177,10,0.1,0.233,0.1,0.0896,0.0896,0.825,0,0,-1.2,1.6
ENSMUSG00000051401,KCTD16,potassium channel tetramerisation domain containing 16,plasma membrane|membrane|cell junction|presynaptic membrane|receptor complex|synapse|postsynaptic membrane|,regulation of G-protein coupled receptor protein signaling pathway|protein homooligomerization|,molecular_function|,10,0,0,10,-0.2,0.689,-0.1,0.0892,-0.0892,0.826,0,0,-1.3,1.5
ENSMUSG00000021789,SFTPA1,surfactant associated protein A1,collagen trimer|extracellular space|multivesicular body|rough endoplasmic reticulum|cytoplasmic vesicle|,positive regulation of phagocytosis|,None,10,0,0,10,-0.2,0.498,-0.1,0.0882,-0.0882,0.826,0,0,-1.7,1.1
ENSMUSG00000032590,APEH,acylpeptide hydrolase,cytoplasm|nuclear membrane|extracellular vesicular exosome|,proteolysis|beta-amyloid metabolic process|,serine-type endopeptidase activity|serine-type peptidase activity|omega peptidase activity|hydrolase activity|poly(A) RNA binding|,10,0,0,10,0.4,1.14,-0.1,0.0873,-0.0873,0.827,0,0,-1.2,1.7
ENSMUSG00000051236,MSRB3,methionine sulfoxide reductase B3,mitochondrion|endoplasmic reticulum|endoplasmic reticulum|,response to oxidative stress|protein repair|protein repair|oxidation-reduction process|,"peptide-methionine (S)-S-oxide reductase activity|zinc ion binding|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor|peptide-methionine (R)-S-oxide reductase activity|peptide-methionine (R)-S-oxide reductase activity|metal ion binding|methionine-R-sulfoxide reductase activity|",10,-0.1,0.172,10,0.1,0.291,0.1,0.087,0.087,0.827,0,0,-0.9,1.9
ENSMUSG00000074364,EHD2,EH-domain containing 2,endosome|plasma membrane|caveola|membrane|perinuclear region of cytoplasm|recycling endosome membrane|extracellular vesicular exosome|,endocytosis|cortical actin cytoskeleton organization|endocytic recycling|protein localization to plasma membrane|positive regulation of myoblast fusion|positive regulation of endocytic recycling|,nucleotide binding|GTPase activity|calcium ion binding|protein binding|ATP binding|GTP binding|hydrolase activity|protein domain specific binding|metal ion binding|,9,0.2,0.755,9,0,0,0.1,0.086,0.086,0.827,0,0,-1,1.9
ENSMUSG00000034910,PYGO1,pygopus 1,nucleus|,kidney development|hematopoietic progenitor cell differentiation|spermatid development|spermatid nucleus differentiation|post-embryonic development|Wnt signaling pathway|protein localization to nucleus|positive regulation of transcription from RNA polymerase II promoter|,protein binding|zinc ion binding|metal ion binding|,10,0,0,10,0.2,0.528,0.1,0.0849,0.0849,0.828,0,0,-1.2,1.7
ENSMUSG00000042240,CRYBB2,"crystallin, beta B2",None,visual perception|camera-type eye development|,structural constituent of eye lens|identical protein binding|protein homodimerization activity|,10,0.2,0.464,10,-0.1,0.0148,0.1,0.0845,0.0845,0.828,0,0,-1.2,1.7
ENSMUSG00000020884,ASGR1,asialoglycoprotein receptor 1,membrane|integral component of membrane|,endocytosis|receptor-mediated endocytosis|cellular response to extracellular stimulus|,asialoglycoprotein receptor activity|carbohydrate binding|protein homodimerization activity|metal ion binding|,10,-0.1,0.085,10,-0.1,0.00623,-0.1,0.0831,-0.0831,0.828,0,0,-1.5,1.4
ENSMUSG00000059920,4930453N24RIK,RIKEN cDNA 4930453N24 gene,cellular_component|,apoptotic process|biological_process|,molecular_function|,10,0.3,1.04,10,0,0,0.1,0.083,0.083,0.828,0,0,-0.9,1.9
ENSMUSG00000033623,PCGF3,polycomb group ring finger 3,nucleus|PcG protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|zinc ion binding|metal ion binding|,10,0.1,0.15,10,0,0,0.1,0.0825,0.0825,0.829,0,0,-1.2,1.8
ENSMUSG00000029490,MFSD7A,major facilitator superfamily domain containing 7A,cellular_component|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0.1,0.122,10,-0.1,0.173,-0.1,0.0768,-0.0768,0.831,0,0,-1.1,1.7
ENSMUSG00000028613,LRP8,"low density lipoprotein receptor-related protein 8, apolipoprotein e receptor",extracellular region|extracellular space|microtubule associated complex|plasma membrane|caveola|postsynaptic density|membrane|integral component of membrane|axon|dendrite|neuronal cell body|receptor complex|,negative regulation of transcription from RNA polymerase II promoter|endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|ammon gyrus development|hippocampus development|layer formation in cerebral cortex|positive regulation of CREB transcription factor activity|reelin-mediated signaling pathway|positive regulation of protein kinase activity|positive regulation of peptidyl-tyrosine phosphorylation|regulation of synaptic transmission|positive regulation of dendritic spine morphogenesis|positive regulation of protein tyrosine kinase activity|positive regulation of dendrite development|,glycoprotein binding|low-density lipoprotein receptor activity|calcium ion binding|protein binding|high-density lipoprotein particle binding|kinesin binding|very-low-density lipoprotein particle receptor activity|apolipoprotein binding|reelin receptor activity|calcium-dependent protein binding|,10,0.1,0.0497,10,0.1,0.0315,0.1,0.0739,0.0739,0.832,0,0,-1.3,1.7
ENSMUSG00000021557,AGTPBP1,ATP/GTP binding protein 1,nucleus|cytoplasm|mitochondrion|cytosol|,eye photoreceptor cell differentiation|proteolysis|mitochondrion organization|adult walking behavior|cell death|cerebellum development|cerebellar Purkinje cell layer development|cerebellar Purkinje cell differentiation|olfactory bulb development|C-terminal protein deglutamylation|protein side chain deglutamylation|neurotransmitter metabolic process|neuromuscular process|neuromuscular process|retina development in camera-type eye|,carboxypeptidase activity|metallocarboxypeptidase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|tubulin binding|hydrolase activity|metal ion binding|,10,-0.2,0.722,10,0.3,0.449,-0.1,0.0728,-0.0728,0.833,0,0,-1.3,1.5
ENSMUSG00000034403,PJA1,"praja ring finger 1, E3 ubiquitin protein ligase",cytoplasm|,protein ubiquitination|protein catabolic process|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,0.856,10,0,0,-0.2,0.0707,-0.0707,0.834,0,0,-2,0.7
ENSMUSG00000038812,TRMT112,tRNA methyltransferase 11-2,protein complex|extracellular vesicular exosome|,peptidyl-glutamine methylation|,protein methyltransferase activity|,7,0,0,7,0.2,0.302,0.1,0.0688,0.0688,0.835,0,0,-1.3,1.9
ENSMUSG00000032869,PSMF1,"proteasome (prosome, macropain) inhibitor subunit 1",proteasome complex|cytoplasm|endoplasmic reticulum|cytosol|membrane|,ubiquitin-dependent protein catabolic process|negative regulation of proteasomal protein catabolic process|,proteasome binding|,8,0.3,0.746,9,-0.1,0.308,-0.1,0.0683,-0.0683,0.835,0,0,-1.1,1.9
ENSMUSG00000047547,CLTB,"clathrin, light polypeptide (Lcb)",trans-Golgi network|plasma membrane|coated pit|membrane|clathrin coat|clathrin coat of trans-Golgi network vesicle|clathrin coat of coated pit|cytoplasmic vesicle|ciliary membrane|,intracellular protein transport|biological_process|vesicle-mediated transport|,structural molecule activity|peptide binding|,10,-0.1,0.101,10,0.3,0.81,-0.1,0.0681,-0.0681,0.835,0,0,-1,1.8
ENSMUSG00000035847,IDS,iduronate 2-sulfatase,lysosome|,metabolic process|,catalytic activity|iduronate-2-sulfatase activity|protein binding|sulfuric ester hydrolase activity|hydrolase activity|metal ion binding|,9,0.1,0.0451,9,0.1,0.0288,0.1,0.0672,0.0672,0.835,0,0,-1.2,1.8
ENSMUSG00000046750,BC089491,cDNA sequence BC089491,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.157,-0.1,0.0664,-0.0664,0.836,0,0,-1.4,1.6
ENSMUSG00000025145,LRRC45,leucine rich repeat containing 45,centrosome|,biological_process|,molecular_function|,10,-0.1,0.385,10,0.1,0.0244,-0.1,0.065,-0.065,0.836,0,0,-1.9,1.2
ENSMUSG00000030733,SH2B1,SH2B adaptor protein 1,ruffle|nucleus|cytoplasm|membrane|,cellular component movement|lamellipodium assembly|intracellular signal transduction|positive regulation of mitosis|regulation of DNA biosynthetic process|,signal transducer activity|protein binding|,10,-0.1,0.207,10,0.7,0.824,0.1,0.064,0.064,0.837,0,0,-0.8,2
ENSMUSG00000061298,AGBL4,ATP/GTP binding protein-like 4,cytoplasm|cytosol|,proteolysis|C-terminal protein deglutamylation|protein side chain deglutamylation|,carboxypeptidase activity|metallocarboxypeptidase activity|protein binding|peptidase activity|metallopeptidase activity|zinc ion binding|tubulin binding|hydrolase activity|metal ion binding|,10,0.3,1.4,10,0,0,0.1,0.0635,0.0635,0.837,0,0,-1.2,1.6
ENSMUSG00000043410,HFM1,"HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)",cellular_component|,resolution of meiotic recombination intermediates|,nucleotide binding|molecular_function|helicase activity|ATP binding|hydrolase activity|,10,0,0,10,0.2,0.19,-0.1,0.0634,-0.0634,0.837,0,0,-1.2,1.7
ENSMUSG00000033368,TRIM69,tripartite motif-containing 69,nucleus|cytoplasm|nuclear speck|,apoptotic process|protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.21,10,0.5,0.229,-0.1,0.063,-0.063,0.837,0,0,-1,1.8
ENSMUSG00000024901,PELI3,pellino 3,cellular_component|,Toll signaling pathway|negative regulation of tumor necrosis factor-mediated signaling pathway|negative regulation of tumor necrosis factor-mediated signaling pathway|protein ubiquitination|negative regulation of protein ubiquitination|negative regulation of type I interferon production|negative regulation of Toll signaling pathway|defense response to Gram-negative bacterium|regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway|positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway|protein K63-linked ubiquitination|negative regulation of extrinsic apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.437,10,0,0,0.1,0.0627,0.0627,0.837,0,0,-1.1,1.8
ENSMUSG00000031548,SFRP1,secreted frizzled-related protein 1,extracellular region|proteinaceous extracellular matrix|extracellular space|intracellular|cytoplasm|cytosol|plasma membrane|plasma membrane|cell surface|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,"somitogenesis|neural tube closure|vasculature development|hematopoietic progenitor cell differentiation|regulation of transcription from RNA polymerase II promoter|proteolysis|signal transduction|multicellular organismal development|brain development|positive regulation of cell proliferation|negative regulation of cell proliferation|male gonad development|female gonad development|dorsal/ventral axis specification|anterior/posterior pattern specification|regulation of cell cycle process|negative regulation of gene expression|negative regulation of gene expression|negative regulation of epithelial to mesenchymal transition|neural crest cell fate commitment|response to organic cyclic compound|Wnt signaling pathway|neural tube development|actin cytoskeleton organization|hemopoiesis|cell differentiation|positive regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|regulation of ossification|negative regulation of ossification|negative regulation of ossification|positive regulation of cell growth|negative regulation of cell growth|negative regulation of cell migration|negative regulation of BMP signaling pathway|negative regulation of osteoblast proliferation|negative regulation of osteoblast proliferation|substrate adhesion-dependent cell spreading|somatic stem cell maintenance|response to drug|response to drug|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of JUN kinase activity|cellular response to fibroblast growth factor stimulus|negative regulation of B cell differentiation|negative regulation of B cell differentiation|positive regulation of fat cell differentiation|negative regulation of osteoblast differentiation|negative regulation of osteoclast differentiation|negative regulation of osteoclast differentiation|positive regulation of smoothened signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|development of primary male sexual characteristics|negative regulation of insulin secretion|negative regulation of bone remodeling|negative regulation of fibroblast proliferation|digestive tract morphogenesis|positive regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|negative regulation of peptidyl-tyrosine phosphorylation|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|hematopoietic stem cell differentiation|bone trabecula formation|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis|regulation of branching involved in prostate gland morphogenesis|negative regulation of androgen receptor signaling pathway|cellular response to tumor necrosis factor|cellular response to growth factor stimulus|cellular response to estrogen stimulus|cellular response to estrogen stimulus|cellular response to X-ray|cellular response to heparin|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|regulation of establishment of planar polarity|planar cell polarity pathway involved in neural tube closure|Wnt signaling pathway involved in somitogenesis|convergent extension involved in somitogenesis|positive regulation of canonical Wnt signaling pathway|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of planar cell polarity pathway involved in axis elongation|positive regulation of non-canonical Wnt signaling pathway|negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification|negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of fibroblast apoptotic process|positive regulation of fibroblast apoptotic process|positive regulation of extrinsic apoptotic signaling pathway|",cysteine-type endopeptidase activity|frizzled binding|protein binding|drug binding|heparin binding|Wnt-protein binding|Wnt-protein binding|PDZ domain binding|identical protein binding|Wnt-activated receptor activity|,10,-0.2,0.337,10,0,0,0.1,0.0616,0.0616,0.838,0,0,-1.5,1.4
ENSMUSG00000022098,BMP1,bone morphogenetic protein 1,extracellular region|proteinaceous extracellular matrix|extracellular space|Golgi apparatus|membrane-bounded vesicle|,ossification|proteolysis|proteolysis|multicellular organismal development|cell differentiation|cartilage development|positive regulation of cartilage development|,metalloendopeptidase activity|metalloendopeptidase activity|cytokine activity|calcium ion binding|protein binding|growth factor activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,-0.2,0.249,-0.1,0.0603,-0.0603,0.838,0,0,-1.8,1.1
ENSMUSG00000004270,LPCAT3,lysophosphatidylcholine acyltransferase 3,endoplasmic reticulum|membrane|membrane|integral component of membrane|,lipid metabolic process|phospholipid biosynthetic process|regulation of plasma lipoprotein particle levels|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|1-acylglycerophosphocholine O-acyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0,0,10,0.1,0.322,0.1,0.0603,0.0603,0.838,0,0,-1.3,1.7
ENSMUSG00000041895,WIPI1,"WD repeat domain, phosphoinositide interacting 1",pre-autophagosomal structure|autophagic vacuole membrane|cytoplasm|endosome|Golgi apparatus|trans-Golgi network|cytoskeleton|endosome membrane|membrane|cytoplasmic vesicle|pre-autophagosomal structure membrane|,"autophagy|vesicle targeting, trans-Golgi to endosome|","receptor binding|estrogen receptor binding|phosphatidylinositol-3-phosphate binding|androgen receptor binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0.1,0.377,9,0,0,0.1,0.0589,0.0589,0.839,0,0,-1.3,1.7
ENSMUSG00000028391,WDR31,WD repeat domain 31,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.11,0.1,0.0581,0.0581,0.839,0,0,-1.4,1.6
ENSMUSG00000023033,SCN8A,"sodium channel, voltage-gated, type VIII, alpha",voltage-gated sodium channel complex|voltage-gated sodium channel complex|plasma membrane|plasma membrane|membrane|integral component of membrane|Z disc|dendrite|node of Ranvier|node of Ranvier|sodium channel complex|neuronal cell body|axon initial segment|,transport|ion transport|sodium ion transport|sodium ion transport|muscle organ development|sensory perception of sound|locomotory behavior|adult walking behavior|adult locomotory behavior|response to toxic substance|neuronal action potential|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|neuromuscular process|transmembrane transport|membrane depolarization during action potential|,nucleotide binding|ion channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|sodium channel activity|protein binding|ATP binding|sodium ion binding|,10,0.1,0.126,10,-0.8,1.5,-0.2,0.058,-0.058,0.839,0,0,-2,0.7
ENSMUSG00000055415,ATP10B,"ATPase, class V, type 10B",endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,nucleotide binding|molecular_function|ATP binding|hydrolase activity|,10,0,0,10,-0.2,0.363,-0.1,0.0543,-0.0543,0.841,0,0,-1.5,1.5
ENSMUSG00000025381,CNPY2,canopy 2 homolog (zebrafish),cellular_component|endoplasmic reticulum|,negative regulation of gene expression|regulation of low-density lipoprotein particle clearance|positive regulation of low-density lipoprotein particle receptor biosynthetic process|,molecular_function|,10,-0.1,0.323,10,0,0,-0.1,0.0541,-0.0541,0.841,0,0,-1.5,1.5
ENSMUSG00000024516,SEC11C,SEC11 homolog C (S. cerevisiae),endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,signal peptide processing|proteolysis|biological_process|,peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0.2,0.269,0.1,0.0535,0.0535,0.841,0,0,-0.9,1.9
ENSMUSG00000062646,GANC,"glucosidase, alpha; neutral C",cellular_component|,carbohydrate metabolic process|glucose metabolic process|metabolic process|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|alpha-glucosidase activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|carbohydrate binding|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,0.5,1.04,10,0,0,0.3,0.0515,0.0515,0.842,0,0,-0.8,2
ENSMUSG00000028600,PODN,podocan,extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|,negative regulation of cell proliferation|negative regulation of cell migration|,collagen binding|,10,-0.1,0.154,10,0.1,0.258,0.1,0.05,0.05,0.842,0,0,-1.5,1.4
ENSMUSG00000005483,DNAJB1,"DnaJ (Hsp40) homolog, subfamily B, member 1",nucleus|cytoplasm|cytosol|extracellular vesicular exosome|,protein folding|response to stress|positive regulation of ATPase activity|chaperone mediated protein folding requiring cofactor|chaperone cofactor-dependent protein refolding|negative regulation of inclusion body assembly|,ATPase activator activity|Hsp70 protein binding|unfolded protein binding|chaperone binding|ATPase binding|,10,0,0,10,-0.5,0.566,-0.1,0.049,-0.049,0.843,0,0,-1.8,1.1
ENSMUSG00000060862,ZBTB40,zinc finger and BTB domain containing 40,nucleus|,cellular response to DNA damage stimulus|,molecular_function|metal ion binding|,10,0,0,10,0.1,0.157,0.1,0.0447,0.0447,0.844,0,0,-1.2,1.7
ENSMUSG00000079110,CAPN3,calpain 3,intracellular|nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|plasma membrane|myofibril|Z disc|T-tubule|protein complex|,"autolysis|protein complex assembly|proteolysis|proteolysis|positive regulation of satellite cell activation involved in skeletal muscle regeneration|response to muscle activity|myofibril assembly|negative regulation of protein sumoylation|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of I-kappaB kinase/NF-kappaB signaling|regulation of I-kappaB kinase/NF-kappaB signaling|sarcomere organization|regulation of myoblast differentiation|positive regulation of proteolysis|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|regulation of catalytic activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of release of sequestered calcium ion into cytosol|response to calcium ion|muscle structure development|G1 to G0 transition involved in cell differentiation|cellular response to calcium ion|cellular response to salt stress|protein localization to membrane|self proteolysis|sodium-dependent self proteolysis|",catalytic activity|calcium-dependent cysteine-type endopeptidase activity|calcium-dependent cysteine-type endopeptidase activity|receptor binding|calcium ion binding|protein binding|peptidase activity|cysteine-type peptidase activity|structural constituent of muscle|hydrolase activity|enzyme binding|sodium ion binding|titin binding|protein complex scaffold|metal ion binding|ligase regulator activity|,10,-0.2,0.412,10,0,0,-0.1,0.0443,-0.0443,0.844,0,0,-1.5,1.4
ENSMUSG00000052565,HIST1H1D,"histone cluster 1, H1d",nucleosome|nuclear chromatin|nucleus|chromosome|nuclear euchromatin|,nucleosome assembly|nucleosome positioning|,DNA binding|protein binding|chromatin DNA binding|poly(A) RNA binding|,10,0.2,0.653,10,0,0,0.1,0.0423,0.0423,0.845,0,0,-1.6,1.3
ENSMUSG00000022855,SENP2,SUMO/sentrin specific peptidase 2,nucleus|nuclear pore|cytoplasm|membrane|nuclear body|PML body|cytoplasmic vesicle|,"positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|transport|heart development|dorsal/ventral axis specification|protein transport|Wnt signaling pathway|protein desumoylation|protein desumoylation|negative regulation of protein binding|regulation of DNA endoreduplication|negative regulation of chromatin binding|negative regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|mRNA transport|regulation of protein metabolic process|trophoblast giant cell differentiation|labyrinthine layer development|spongiotrophoblast layer development|negative regulation of signal transduction by p53 class mediator|regulation of G1/S transition of mitotic cell cycle|",peptidase activity|cysteine-type peptidase activity|hydrolase activity|SUMO-specific protease activity|SUMO-specific protease activity|protein domain specific binding|,10,-0.2,0.161,10,0.5,0.346,0.1,0.0412,0.0412,0.846,0,0,-1.3,1.7
ENSMUSG00000052656,RNF103,ring finger protein 103,endoplasmic reticulum|membrane|integral component of membrane|,protein ubiquitination|ER-associated ubiquitin-dependent protein catabolic process|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.188,9,-0.3,0.729,-0.2,0.0402,-0.0402,0.846,0,0,-1.7,1.1
ENSMUSG00000029810,TMEM176B,transmembrane protein 176B,nucleus|membrane|integral component of membrane|,cell differentiation|negative regulation of dendritic cell differentiation|,protein binding|,10,0,0,10,0.1,0.076,0.1,0.038,0.038,0.847,0,0,-1.7,1.1
ENSMUSG00000031898,DPEP3,dipeptidase 3,membrane|anchored component of membrane|,proteolysis|meiotic nuclear division|,protein binding|peptidase activity|metalloexopeptidase activity|metallopeptidase activity|dipeptidyl-peptidase activity|hydrolase activity|dipeptidase activity|metal ion binding|,10,0,0,10,-0.1,0.116,-0.1,0.0332,-0.0332,0.849,0,0,-1.7,1.6
ENSMUSG00000026088,MITD1,"MIT, microtubule interacting and transport, domain containing 1",endosome|membrane|extrinsic component of membrane|midbody|midbody|intracellular membrane-bounded organelle|extracellular vesicular exosome|,mitotic cytokinesis|cytokinetic cell separation|transport|cell cycle|negative regulation of protein binding|cell division|mitotic cytokinetic cell separation|,protein domain specific binding|phosphatidylinositol binding|protein homodimerization activity|,10,0,0,10,-0.2,0.187,0.1,0.0324,0.0324,0.849,0,0,-1.1,1.8
ENSMUSG00000004947,DTX2,deltex 2 homolog (Drosophila),nucleus|nucleus|cytoplasm|nuclear membrane|,Notch signaling pathway|Notch signaling pathway|,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.63,10,0,0,-0.1,0.0301,-0.0301,0.85,0,0,-1.4,1.6
ENSMUSG00000042766,TRIM46,tripartite motif-containing 46,cellular_component|intracellular|,biological_process|,zinc ion binding|metal ion binding|,10,0,0,10,-0.2,0.209,-0.1,0.0288,-0.0288,0.851,0,0,-1.7,1.2
ENSMUSG00000055401,FBXO6,F-box protein 6,cytoplasm|SCF ubiquitin ligase complex|SCF ubiquitin ligase complex|,DNA repair|glycoprotein catabolic process|cellular response to DNA damage stimulus|response to unfolded protein|protein ubiquitination|ER-associated ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|,glycoprotein binding|ubiquitin-protein transferase activity|protein binding|carbohydrate binding|,8,0,0,8,-0.3,0.523,-0.1,0.0284,-0.0284,0.851,0,0,-1.8,1.2
ENSMUSG00000022043,TRIM35,tripartite motif-containing 35,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|,apoptotic process|negative regulation of cell proliferation|positive regulation of apoptotic process|positive regulation of apoptotic process|innate immune response|negative regulation of mitotic cell cycle|negative regulation of viral release from host cell|,zinc ion binding|metal ion binding|,10,0,0,10,-0.1,0.158,-0.1,0.0271,-0.0271,0.852,0,0,-1.7,1.3
ENSMUSG00000035547,CAPN5,calpain 5,intracellular|cytoplasm|cell surface|extracellular vesicular exosome|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0,0,10,0.2,0.412,0.1,0.0269,0.0269,0.852,0,0,-1.5,1.4
ENSMUSG00000031770,HERPUD1,"homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1",endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein catabolic process|cellular calcium ion homeostasis|response to unfolded protein|endoplasmic reticulum unfolded protein response|endoplasmic reticulum unfolded protein response|regulation of protein ubiquitination|positive regulation of protein binding|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|,protein binding|,10,0,0,10,0.2,0.482,0.1,0.0263,0.0263,0.852,0,0,-1.2,1.7
ENSMUSG00000025196,CPN1,"carboxypeptidase N, polypeptide 1",extracellular region|extracellular space|,proteolysis|proteolysis|bradykinin catabolic process|response to glucocorticoid|,carboxypeptidase activity|carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.036,10,0,0,0.1,0.0242,0.0242,0.853,0,0,-1.2,1.8
ENSMUSG00000004462,TBCCD1,TBCC domain containing 1,cytoplasm|cytoskeleton|spindle pole centrosome|,cell morphogenesis|cytoskeleton organization|regulation of cell shape|regulation of cell migration|maintenance of centrosome location|maintenance of Golgi location|,molecular_function|actin binding|,10,0,0,10,-0.2,0.362,-0.1,0.0239,-0.0239,0.853,0,0,-1.9,1
ENSMUSG00000046841,CKAP4,cytoskeleton-associated protein 4,cytoplasm|endoplasmic reticulum|endoplasmic reticulum|lipid particle|cytoskeleton|plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,poly(A) RNA binding|,10,-0.4,0.892,10,0.1,0.219,0.1,0.0214,0.0214,0.854,0,0,-1.7,1.1
ENSMUSG00000029755,DLX5,distal-less homeobox 5,nuclear chromatin|nucleus|cytoplasm|,"ossification|osteoblast differentiation|endochondral ossification|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|axonogenesis|axon guidance|cell proliferation|embryonic limb morphogenesis|BMP signaling pathway|epithelial cell differentiation|inner ear morphogenesis|inner ear morphogenesis|ear development|positive regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|anatomical structure formation involved in morphogenesis|positive regulation of epithelial cell proliferation|palate development|palate development|olfactory pit development|head development|face morphogenesis|bone morphogenesis|cellular response to BMP stimulus|positive regulation of canonical Wnt signaling pathway|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|HMG box domain binding|,10,-0.1,0.0841,10,0.5,1.84,0.2,0.0207,0.0207,0.855,0,0,-0.8,1.9
ENSMUSG00000056054,S100A8,S100 calcium binding protein A8 (calgranulin A),extracellular region|extracellular space|nucleus|cytoplasm|cytoskeleton|plasma membrane|membrane|extracellular vesicular exosome|,immune system process|leukocyte migration involved in inflammatory response|autophagy|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|chemotaxis|inflammatory response|neutrophil chemotaxis|innate immune response|regulation of inflammatory response|positive regulation of inflammatory response|neutrophil aggregation|positive regulation of intrinsic apoptotic signaling pathway|,calcium ion binding|microtubule binding|zinc ion binding|antioxidant activity|Toll-like receptor 4 binding|metal ion binding|arachidonic acid binding|RAGE receptor binding|,10,-0.1,0.233,10,0.1,0.0117,-0.1,0.0206,-0.0206,0.855,0,0,-1.5,1.4
ENSMUSG00000031825,CRISPLD2,cysteine-rich secretory protein LCCL domain containing 2,extracellular region|transport vesicle|extracellular matrix|,extracellular matrix organization|face morphogenesis|,glycosaminoglycan binding|heparin binding|,10,0,0,10,-0.4,1,-0.1,0.018,-0.018,0.856,0,0,-1.7,1.3
ENSMUSG00000062542,SYT9,synaptotagmin IX,synaptic vesicle|membrane|integral component of membrane|cell junction|secretory granule|secretory granule membrane|dense core granule|dense core granule|cytoplasmic vesicle|synapse|,transport|regulation of calcium ion-dependent exocytosis|positive regulation of calcium ion-dependent exocytosis|regulation of insulin secretion|,transporter activity|protein binding|identical protein binding|metal ion binding|,10,0,0,10,0.3,0.909,0.2,0.0159,0.0159,0.857,0,0,-1.7,1.3
ENSMUSG00000039146,IFI44L,interferon-induced protein 44 like,cytoplasm|,immune response|,None,10,0.2,0.217,10,0,0,0.1,0.0157,0.0157,0.857,0,0,-1.3,1.6
ENSMUSG00000022324,MATN2,matrilin 2,extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular matrix|,neuron migration|axon guidance|glial cell migration|dendrite regeneration|neuron projection development|response to axon injury|,calcium ion binding|,10,-0.2,0.602,10,0,0,-0.1,0.012,-0.012,0.858,0,0,-2,0.8
ENSMUSG00000026429,UBE2T,ubiquitin-conjugating enzyme E2T (putative),cellular_component|nucleus|,DNA repair|protein monoubiquitination|cellular response to DNA damage stimulus|protein K29-linked ubiquitination|protein K27-linked ubiquitination|protein autoubiquitination|protein K63-linked ubiquitination|protein K48-linked ubiquitination|protein K11-linked ubiquitination|protein K6-linked ubiquitination|,nucleotide binding|chromatin binding|ubiquitin-protein transferase activity|ATP binding|ligase activity|acid-amino acid ligase activity|ubiquitin protein ligase binding|,10,0,0,10,0.2,0.498,0.1,0.0118,0.0118,0.858,0,0,-0.8,2
ENSMUSG00000031220,AWAT2,acyl-CoA wax alcohol acyltransferase 2,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,lipid metabolic process|wax biosynthetic process|,"molecular_function|transferase activity|transferase activity, transferring acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups|long-chain-alcohol O-fatty-acyltransferase activity|retinol O-fatty-acyltransferase activity|",10,-0.1,0.00858,10,0.2,0.224,-0.1,0.00931,-0.00931,0.859,0,0,-1.8,1.1
ENSMUSG00000046785,EPM2AIP1,EPM2A (laforin) interacting protein 1,nucleus|cytoplasm|endoplasmic reticulum|,response to insulin|positive regulation of glycogen biosynthetic process|positive regulation of glycogen (starch) synthase activity|,protein binding|,10,-0.2,0.282,10,0,0,-0.1,0.00817,-0.00817,0.86,0,0,-1.6,1.4
ENSMUSG00000028883,SEMA3A,"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A",extracellular region|membrane|axon|dendrite|,neuron migration|regulation of heart rate|apoptotic process|multicellular organismal development|nervous system development|axon guidance|axon guidance|axon guidance|axonal fasciculation|negative regulation of epithelial cell migration|nerve development|olfactory bulb development|gonadotrophin-releasing hormone neuronal migration to the hypothalamus|cell differentiation|negative regulation of axon extension|negative regulation of axon extension|negative regulation of axon extension|dendrite morphogenesis|regulation of axon extension involved in axon guidance|regulation of axon extension involved in axon guidance|negative regulation of axon extension involved in axon guidance|negative regulation of axon extension involved in axon guidance|axon extension involved in axon guidance|negative chemotaxis|negative chemotaxis|axonogenesis involved in innervation|dichotomous subdivision of terminal units involved in salivary gland branching|dichotomous subdivision of terminal units involved in salivary gland branching|sympathetic ganglion development|semaphorin-plexin signaling pathway|sympathetic neuron projection extension|sympathetic neuron projection guidance|neural crest cell migration involved in autonomic nervous system development|semaphorin-plexin signaling pathway involved in neuron projection guidance|neural crest cell migration involved in sympathetic nervous system development|positive regulation of male gonad development|positive regulation of neuron migration|,receptor activity|semaphorin receptor binding|neuropilin binding|chemorepellent activity|,10,-0.2,0.98,10,0,0,-0.1,0.0072,-0.0072,0.86,0,0,-1.6,1.3
ENSMUSG00000026003,ACADL,"acyl-Coenzyme A dehydrogenase, long-chain",cytoplasm|mitochondrion|mitochondrion|mitochondrial matrix|mitochondrial membrane|,"temperature homeostasis|lipid metabolic process|fatty acid metabolic process|metabolic process|carnitine metabolic process, CoA-linked|fatty acid beta-oxidation using acyl-CoA dehydrogenase|fatty acid beta-oxidation using acyl-CoA dehydrogenase|carnitine catabolic process|long-chain fatty acid catabolic process|cellular lipid catabolic process|negative regulation of fatty acid biosynthetic process|negative regulation of fatty acid oxidation|protein homotetramerization|oxidation-reduction process|regulation of cholesterol metabolic process|","fatty-acyl-CoA binding|acyl-CoA dehydrogenase activity|long-chain-acyl-CoA dehydrogenase activity|long-chain-acyl-CoA dehydrogenase activity|palmitoyl-CoA oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|flavin adenine dinucleotide binding|",10,0.2,0.424,10,-1,0.138,0.1,0.00646,0.00646,0.861,0,0,-2,1
ENSMUSG00000026197,ZFAND2B,"zinc finger, AN1 type domain 2B",cellular_component|endoplasmic reticulum|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.1,0.0819,10,0,0,0.1,0.00485,0.00485,0.861,0,0,-1.4,1.5
ENSMUSG00000035713,USP35,ubiquitin specific peptidase 35,cellular_component|,proteolysis|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.1,0.0024,10,0.1,0.00113,0.1,0.00321,0.00321,0.862,0,0,-1.4,1.5
ENSMUSG00000026582,SELE,"selectin, endothelial cell",extracellular space|caveola|coated pit|membrane|integral component of membrane|cortical cytoskeleton|membrane raft|perinuclear region of cytoplasm|,positive regulation of receptor internalization|positive regulation of leukocyte migration|inflammatory response|cell adhesion|heterophilic cell-cell adhesion|leukocyte cell-cell adhesion|signal transduction|activation of phospholipase C activity|actin filament-based process|leukocyte tethering or rolling|response to interleukin-1|,transmembrane signaling receptor activity|carbohydrate binding|sialic acid binding|phospholipase binding|oligosaccharide binding|,9,0,0,9,0.2,0.219,0.1,0.00304,0.00304,0.862,0,0,-1.1,1.9
ENSMUSG00000025040,FUNDC1,FUN14 domain containing 1,mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|,mitochondrion degradation|response to hypoxia|autophagy|,molecular_function|,10,0,0,10,0.2,0.39,0,0,0,0.863,0,0,-1.5,1.4
ENSMUSG00000015843,RXRG,retinoid X receptor gamma,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|regulation of myelination|steroid hormone mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|retinoic acid receptor signaling pathway|protein homotetramerization|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|9-cis retinoic acid receptor activity|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0.1,0.0904,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000020635,FKBP1B,FK506 binding protein 1b,intracellular|cell|cytoplasm|membrane|sarcoplasmic reticulum|Z disc|sarcoplasmic reticulum membrane|calcium channel complex|calcium channel complex|intracellular membrane-bounded organelle|,protein peptidyl-prolyl isomerization|protein peptidyl-prolyl isomerization|regulation of heart rate|protein folding|smooth muscle contraction|positive regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration|response to glucose|negative regulation of heart rate|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|neuronal action potential propagation|insulin secretion|negative regulation of protein phosphatase type 2B activity|T cell proliferation|positive regulation of axon regeneration|release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion into cytosol|positive regulation of sequestering of calcium ion|cytosolic calcium ion homeostasis|cytosolic calcium ion homeostasis|response to redox state|regulation of ryanodine-sensitive calcium-release channel activity|negative regulation of ryanodine-sensitive calcium-release channel activity|chaperone-mediated protein folding|negative regulation of insulin secretion involved in cellular response to glucose stimulus|,peptidyl-prolyl cis-trans isomerase activity|peptidyl-prolyl cis-trans isomerase activity|receptor binding|protein binding|FK506 binding|FK506 binding|isomerase activity|calcium channel inhibitor activity|calcium channel inhibitor activity|cyclic nucleotide binding|ion channel binding|,10,0.1,0.0217,10,-0.1,0.108,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000002017,FAM98A,"family with sequence similarity 98, member A",cellular_component|,biological_process|,poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000029456,ACAD10,"acyl-Coenzyme A dehydrogenase family, member 10",mitochondrion|,metabolic process|oxidation-reduction process|,"acyl-CoA dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|transferase activity, transferring phosphorus-containing groups|hydrolase activity|short-branched-chain-acyl-CoA dehydrogenase activity|very-long-chain-acyl-CoA dehydrogenase activity|4-methyloctanoyl-CoA dehydrogenase activity|naphthyl-2-methyl-succinyl-CoA dehydrogenase activity|2-methylhexanoyl-CoA dehydrogenase activity|propionyl-CoA dehydrogenase activity|thiol-driven fumarate reductase activity|flavin adenine dinucleotide binding|coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity|coenzyme F420-dependent 2,4-dinitrophenol reductase activity|medium-chain-acyl-CoA dehydrogenase activity|",10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000052949,RNF157,ring finger protein 157,cellular_component|,biological_process|,zinc ion binding|metal ion binding|,10,0,0,10,-0.3,0.951,0,0,0,0.863,0,0,-1.7,1.2
ENSMUSG00000047854,STX19,syntaxin 19,membrane|integral component of membrane|,intracellular protein transport|biological_process|vesicle-mediated transport|,molecular_function|SNAP receptor activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.8
ENSMUSG00000051036,TTC24,tetratricopeptide repeat domain 24,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.188,10,0.3,0.808,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000061171,SLC38A11,"solute carrier family 38, member 11",cellular_component|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|amino acid transport|biological_process|,molecular_function|,10,0.1,0.152,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000022602,ARC,activity regulated cytoskeletal-associated protein,cytoplasm|endosome|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|cell junction|cytoplasmic vesicle|cell projection|synapse|postsynaptic membrane|,endocytosis|cytoskeleton organization|multicellular organismal development|endoderm development|anterior/posterior pattern specification|cell migration|regulation of cell morphogenesis|,actin binding|protein binding|,10,0,0,10,0.1,0.139,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000003865,GYS1,"glycogen synthase 1, muscle",cytoplasm|membrane|inclusion body|,glycogen metabolic process|glycogen biosynthetic process|glycogen biosynthetic process|heart development|metabolic process|,"catalytic activity|glycogen (starch) synthase activity|glycogen (starch) synthase activity|protein binding|glucose binding|transferase activity|transferase activity, transferring glycosyl groups|protein kinase binding|glycogen synthase activity, transferring glucose-1-phosphate|",10,0,0,10,0.1,0.0583,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000020657,DNAJC27,"DnaJ (Hsp40) homolog, subfamily C, member 27",mitochondrion|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000068735,TRP53I11,transformation related protein 53 inducible protein 11,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.308,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000047632,FGFBP3,fibroblast growth factor binding protein 3,extracellular region|,positive regulation of vascular permeability|positive regulation of fibroblast growth factor receptor signaling pathway|,heparin binding|fibroblast growth factor binding|growth factor binding|,10,0.2,0.33,10,0,0,0,0,0,0.863,0,0,-1.4,1.5
ENSMUSG00000022390,ZC3H7B,zinc finger CCCH type containing 7B,cellular_component|,biological_process|,poly(A) RNA binding|metal ion binding|,10,-0.3,0.639,10,0,0,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000075316,SCN9A,"sodium channel, voltage-gated, type IX, alpha",voltage-gated sodium channel complex|plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|inflammatory response|response to toxic substance|post-embryonic development|neuronal action potential|neuronal action potential|regulation of ion transmembrane transport|sodium ion transmembrane transport|sodium ion transmembrane transport|behavioral response to pain|transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated sodium channel activity|sodium channel activity|sodium ion binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-2,1.1
ENSMUSG00000021390,OGN,osteoglycin,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|,None,growth factor activity|,10,0,0,10,-0.1,0.0223,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000005362,CRBN,cereblon,nucleus|nucleolus|cytoplasm|membrane|Cul4A-RING E3 ubiquitin ligase complex|,proteolysis|protein ubiquitination|negative regulation of protein homooligomerization|negative regulation of ion transmembrane transport|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of protein homodimerization activity|,ATP-dependent peptidase activity|,10,0,0,10,0.1,0.0217,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000005917,OTX1,orthodenticle homolog 1,nucleus|,"regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|anterior/posterior pattern specification|metencephalon development|forebrain development|midbrain development|inner ear morphogenesis|inner ear morphogenesis|positive regulation of transcription from RNA polymerase II promoter|diencephalon morphogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.8
ENSMUSG00000021124,VTI1B,vesicle transport through interaction with t-SNAREs 1B,lysosome|lysosomal membrane|endosome|Golgi apparatus|Golgi apparatus|membrane|integral component of membrane|late endosome membrane|perinuclear region of cytoplasm|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,SNARE binding|protein binding|,9,0,0,9,0,0,0,0,0,0.863,0,0,-1.3,1.8
ENSMUSG00000036606,PLXNB2,plexin B2,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,neural tube closure|regulation of protein phosphorylation|signal transduction|multicellular organismal development|neuroblast proliferation|brain development|regulation of cell shape|regulation of Rho GTPase activity|positive regulation of axonogenesis|semaphorin-plexin signaling pathway|regulation of neuron migration|,receptor activity|protein binding|semaphorin receptor activity|,10,0,0,10,0.1,0.0389,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000060681,SLC9A6,"solute carrier family 9 (sodium/hydrogen exchanger), member 6",mitochondrion|endosome|early endosome|late endosome|endoplasmic reticulum membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|dendrite|cytoplasmic vesicle|early endosome membrane|axon terminus|axonal spine|synapse|recycling endosome|recycling endosome membrane|,transport|ion transport|sodium ion transport|proton transport|brain-derived neurotrophic factor receptor signaling pathway|axon extension|neuron projection morphogenesis|synapse organization|regulation of neurotrophin TRK receptor signaling pathway|dendritic spine development|dendrite extension|,molecular_function|antiporter activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000021732,FGF10,fibroblast growth factor 10,extracellular region|extracellular space|extracellular space|cell|nucleus|plasma membrane|cell surface|extracellular matrix|,"establishment of mitotic spindle orientation|activation of MAPK activity|organ induction|organ induction|blood vessel remodeling|metanephros morphogenesis|chemotaxis|cell-cell signaling|cell-cell signaling|determination of left/right symmetry|salivary gland development|salivary gland morphogenesis|positive regulation of cell proliferation|negative regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|epidermis development|regulation of smoothened signaling pathway|embryonic pattern specification|organ morphogenesis|organ morphogenesis|regulation of gene expression|epithelial cell migration|positive regulation of epithelial cell migration|positive regulation of epithelial cell migration|positive regulation of keratinocyte proliferation|pituitary gland development|positive regulation of Wnt signaling pathway|lung development|lung development|embryonic genitalia morphogenesis|epithelial cell differentiation|thyroid gland development|otic vesicle formation|positive regulation of vascular endothelial growth factor receptor signaling pathway|pancreas development|hair follicle morphogenesis|embryonic camera-type eye development|actin cytoskeleton reorganization|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|positive regulation of ATPase activity|lacrimal gland development|lacrimal gland development|regulation of activin receptor signaling pathway|protein localization to cell surface|somatic stem cell maintenance|limb morphogenesis|organ growth|wound healing|inner ear morphogenesis|inner ear morphogenesis|odontogenesis of dentin-containing tooth|muscle cell fate commitment|positive regulation of MAPK cascade|keratinocyte proliferation|negative regulation of cell differentiation|positive regulation of DNA repair|positive regulation of DNA replication|positive regulation of Notch signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of Ras protein signal transduction|regulation of saliva secretion|positive regulation of fibroblast proliferation|lung alveolus development|lung alveolus development|blood vessel morphogenesis|spleen development|thymus development|embryonic digestive tract morphogenesis|digestive tract development|embryonic digestive tract development|organ formation|epidermis morphogenesis|semicircular canal morphogenesis|branching morphogenesis of an epithelial tube|female genitalia morphogenesis|male genitalia morphogenesis|positive regulation of lymphocyte proliferation|epithelial cell proliferation|epithelial cell proliferation|urothelial cell proliferation|positive regulation of urothelial cell proliferation|regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|white fat cell differentiation|positive chemotaxis|positive chemotaxis|induction of positive chemotaxis|smooth muscle cell differentiation|positive regulation of keratinocyte migration|radial glial cell differentiation|limb development|limb bud formation|lung morphogenesis|lung epithelium development|lung saccule development|bronchiole morphogenesis|epithelial tube branching involved in lung morphogenesis|epithelial tube branching involved in lung morphogenesis|branching involved in salivary gland morphogenesis|branching involved in salivary gland morphogenesis|bud outgrowth involved in lung branching|bud elongation involved in lung branching|mesenchymal-epithelial cell signaling involved in lung development|Type II pneumocyte differentiation|prostatic bud formation|respiratory system development|mammary gland specification|fibroblast growth factor receptor signaling pathway involved in mammary gland specification|fibroblast growth factor receptor signaling pathway involved in mammary gland specification|fibroblast growth factor receptor signaling pathway involved in mammary gland specification|mammary gland bud formation|submandibular salivary gland formation|epithelial cell proliferation involved in salivary gland morphogenesis|epithelial cell proliferation involved in salivary gland morphogenesis|regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling|branch elongation involved in salivary gland morphogenesis|semicircular canal fusion|mesenchymal cell differentiation involved in lung development|secretion by lung epithelial cell involved in lung growth|lung proximal/distal axis specification|tear secretion|positive regulation of white fat cell proliferation|ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|Harderian gland development|negative regulation of cell cycle arrest|positive regulation of hair follicle cell proliferation|positive regulation of canonical Wnt signaling pathway|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|",receptor binding|fibroblast growth factor receptor binding|type 2 fibroblast growth factor receptor binding|protein binding|growth factor activity|heparin binding|chemoattractant activity|chemoattractant activity|,10,-0.2,0.325,10,0,0,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000067616,KLK11,kallikrein related-peptidase 11,extracellular region|extracellular space|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.2,1.9
ENSMUSG00000040746,RNF167,ring finger protein 167,cytoplasm|membrane|integral component of membrane|,protein polyubiquitination|negative regulation of cell cycle|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000037907,ANKRD13B,ankyrin repeat domain 13b,cellular_component|endosome|plasma membrane|membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000020627,KLHL29,kelch-like 29,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000056211,R3HDM1,R3H domain containing 1,cellular_component|,biological_process|,poly(A) RNA binding|,10,-0.2,0.336,10,0.7,1.41,0,0,0,0.863,0,0,-1.4,1.8
ENSMUSG00000036564,NDRG4,N-myc downstream regulated gene 4,cytoplasm|mitochondrion|endoplasmic reticulum membrane|,positive regulation of neuron projection development|,None,10,0,0,10,0.2,0.142,0,0,0,0.863,0,0,-1.1,1.8
ENSMUSG00000074625,ARHGAP40,Rho GTPase activating protein 40,cellular_component|intracellular|,signal transduction|biological_process|,molecular_function|GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000025702,8-Mar,membrane-associated ring finger (C3HC4) 8,lysosome|endosome|membrane|integral component of membrane|cytoplasmic vesicle|,protein polyubiquitination|immune system process|antigen processing and presentation of peptide antigen via MHC class II|protein ubiquitination|negative regulation of MHC class II biosynthetic process|,"ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|MHC class II protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.404,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000043286,PNPLA1,patatin-like phospholipase domain containing 1,cytoplasm|,lipid metabolic process|biological_process|metabolic process|lipid catabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0,0,10,0.2,0.504,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000035413,TMEM98,transmembrane protein 98,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.121,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000032291,CRABP1,cellular retinoic acid binding protein I,cytoplasm|cytosol|,transport|,retinoic acid binding|transporter activity|retinoid binding|lipid binding|retinal binding|retinol binding|,10,0,0,10,0.3,0.323,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000048732,KLHL11,kelch-like 11,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.619,10,0,0,0,0,0,0.863,0,0,-1.9,1.1
ENSMUSG00000057969,SEMA3B,"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B",extracellular region|membrane|extracellular vesicular exosome|,multicellular organismal development|nervous system development|cell differentiation|,receptor activity|,10,0.1,0.259,10,-0.1,0.0211,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000017774,MYO1C,myosin IC,nucleus|nuclear pore|cytoplasm|mitochondrion|plasma membrane|microvillus|brush border|basal plasma membrane|membrane|membrane|lateral plasma membrane|myosin complex|cytoplasmic vesicle|filamentous actin|stereocilium|cell projection|membrane raft|myosin I complex|extracellular vesicular exosome|,ATP catabolic process|protein targeting|protein targeting to membrane|transport|protein transport|positive regulation of cell migration|positive regulation of cell migration by vascular endothelial growth factor signaling pathway|mRNA transport|positive regulation of protein targeting to membrane|positive regulation of vascular endothelial growth factor signaling pathway|regulation of tight junction assembly|,nucleotide binding|motor activity|actin binding|receptor binding|protein binding|calmodulin binding|ATP binding|phospholipid binding|protein C-terminus binding|actin-dependent ATPase activity|,10,0.1,0.142,10,0,0,0,0,0,0.863,0,0,-1.8,1.1
ENSMUSG00000063661,KRT73,keratin 73,nucleus|intermediate filament|keratin filament|extracellular vesicular exosome|,biological_process|,structural molecule activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000039672,KCNE2,"potassium voltage-gated channel, Isk-related subfamily, gene 2",lysosome|plasma membrane|voltage-gated potassium channel complex|cell surface|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|potassium ion import|cellular protein localization|regulation of ion transmembrane transport|cellular response to drug|regulation of membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|potassium ion export|potassium ion transmembrane transport|potassium ion transmembrane transport|cardiac muscle cell action potential involved in contraction|ventricular cardiac muscle cell action potential|ventricular cardiac muscle cell action potential|membrane repolarization|membrane repolarization during action potential|membrane repolarization during cardiac muscle cell action potential|regulation of heart rate by cardiac conduction|regulation of potassium ion transmembrane transport|positive regulation of proteasomal protein catabolic process|regulation of inward rectifier potassium channel activity|regulation of cyclic nucleotide-gated ion channel activity|regulation of delayed rectifier potassium channel activity|regulation of cation channel activity|,inward rectifier potassium channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|protein binding|potassium channel regulator activity|protein homodimerization activity|ion channel binding|voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000036275,9530068E07RIK,RIKEN cDNA 9530068E07 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000031429,PSMD10,"proteasome (prosome, macropain) 26S subunit, non-ATPase, 10","nucleus|cytoplasm|proteasome regulatory particle, base subcomplex|intermediate filament cytoskeleton|","negative regulation of transcription from RNA polymerase II promoter|apoptotic process|cytoplasmic sequestering of NF-kappaB|positive regulation of cell growth|positive regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of apoptotic process|negative regulation of MAPK cascade|negative regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of cyclin-dependent protein serine/threonine kinase activity|proteasome regulatory particle assembly|negative regulation of release of cytochrome c from mitochondria|",transcription factor binding|,10,0,0,10,0.2,0.0567,0,0,0,0.863,0,0,-1.2,1.9
ENSMUSG00000032911,CSPG4,chondroitin sulfate proteoglycan 4,intracellular|plasma membrane|plasma membrane|membrane|integral component of membrane|cell projection|extracellular vesicular exosome|,activation of MAPK activity|angiogenesis|inflammatory response|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|multicellular organismal development|cell proliferation|glial cell migration|negative regulation of neuron projection development|neuron remodeling|cell differentiation|intracellular signal transduction|tissue remodeling|positive regulation of peptidyl-tyrosine phosphorylation|,signal transducer activity|protein binding|collagen binding|protein kinase binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.3
ENSMUSG00000041670,RIMS1,regulating synaptic membrane exocytosis 1,cell|plasma membrane|membrane|cell junction|presynaptic membrane|synapse|,protein complex assembly|transport|neurotransmitter transport|intracellular protein transport|exocytosis|regulation of membrane potential|regulation of long-term neuronal synaptic plasticity|calcium ion-dependent exocytosis of neurotransmitter|long-term synaptic potentiation|regulation of synaptic vesicle exocytosis|,protein binding|SH3 domain binding|Rab GTPase binding|protein kinase binding|ion channel binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000026941,MAMDC4,MAM domain containing 4,endosome|,biological_process|,molecular_function|,9,-0.3,0.509,9,-1,0.514,0,0,0,0.863,0,0,-2,0.7
ENSMUSG00000055707,KLHL26,kelch-like 26,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000054920,KLHL5,kelch-like 5,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0657,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000027227,SORD,sorbitol dehydrogenase,mitochondrion|cilium|membrane|motile cilium|cell projection|extracellular vesicular exosome|,sorbitol metabolic process|sorbitol catabolic process|response to hormone|sperm motility|fructose biosynthetic process|response to cadmium ion|response to copper ion|L-xylitol catabolic process|L-xylitol metabolic process|oxidation-reduction process|,L-iditol 2-dehydrogenase activity|L-iditol 2-dehydrogenase activity|zinc ion binding|oxidoreductase activity|identical protein binding|metal ion binding|NAD binding|,10,-0.2,0.376,10,0.1,0.244,0,0,0,0.863,0,0,-1.4,1.5
ENSMUSG00000062110,SCFD2,Sec1 family domain containing 2,cellular_component|,transport|vesicle docking involved in exocytosis|biological_process|protein transport|vesicle-mediated transport|,molecular_function|,10,0.1,0.0569,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000049699,UCN2,urocortin 2,extracellular region|extracellular space|,cAMP biosynthetic process|response to stress|digestion|cell proliferation|negative regulation of gene expression|negative regulation of luteinizing hormone secretion|negative regulation of follicle-stimulating hormone secretion|,G-protein coupled receptor binding|receptor binding|receptor binding|hormone activity|protein binding|hormone binding|corticotropin-releasing hormone receptor 2 binding|,10,0,0,10,-0.8,0.151,0,0,0,0.863,0,0,-2,1
ENSMUSG00000059890,UBE4A,ubiquitination factor E4A,cytoplasm|,protein polyubiquitination|,ubiquitin-protein transferase activity|ubiquitin-ubiquitin ligase activity|,10,-0.4,0.215,10,0,0,0,0,0,0.863,0,0,-1.7,1.2
ENSMUSG00000001508,SGCA,"sarcoglycan, alpha (dystrophin-associated glycoprotein)",cytoplasm|cytoskeleton|plasma membrane|integral component of plasma membrane|cell-cell junction|dystrophin-associated glycoprotein complex|dystroglycan complex|sarcoglycan complex|membrane|integral component of membrane|sarcolemma|membrane raft|,muscle contraction|muscle organ development|membrane organization|,calcium ion binding|,10,0.1,0.132,10,0,0,0,0,0,0.863,0,0,-1.9,1.2
ENSMUSG00000025875,TSPAN17,tetraspanin 17,membrane|integral component of membrane|,protein maturation|establishment of protein localization to organelle|,enzyme binding|enzyme binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000024299,ADAMTS10,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10",microfibril|extracellular region|proteinaceous extracellular matrix|extracellular matrix|,proteolysis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,9,-1,0.245,9,0,0,0,0,0,0.863,0,0,-2,1
ENSMUSG00000032375,APH1B,anterior pharynx defective 1b homolog (C. elegans),membrane|integral component of membrane|transport vesicle|,proteolysis|Notch signaling pathway|protein processing|positive regulation of catalytic activity|,endopeptidase activity|,10,0,0,10,0.1,0.0338,0,0,0,0.863,0,0,-1,2
ENSMUSG00000016940,KCTD2,potassium channel tetramerisation domain containing 2,cellular_component|,transport|ion transport|biological_process|protein homooligomerization|,protein complex binding|,10,0.2,0.659,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000091166,TSTD1,thiosulfate sulfurtransferase (rhodanese)-like domain containing 1,cytoplasm|mitochondrion|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000073968,TRIM68,tripartite motif-containing 68,intracellular|nucleus|nucleolus|cytoplasm|Golgi apparatus|,protein autoubiquitination|regulation of androgen receptor signaling pathway|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|histone acetyltransferase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|androgen receptor binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.2,0.355,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000004952,RASA4,RAS p21 protein activator 4,intracellular|cytoplasm|plasma membrane|membrane|intrinsic component of the cytoplasmic side of the plasma membrane|,signal transduction|positive regulation of Ras GTPase activity|intracellular signal transduction|positive regulation of GTPase activity|negative regulation of Ras protein signal transduction|regulation of small GTPase mediated signal transduction|,GTPase activator activity|Ras GTPase activator activity|metal ion binding|,10,-0.1,0.0223,10,0.3,0.335,0,0,0,0.863,0,0,-1.5,1.4
ENSMUSG00000027702,LRRC34,leucine rich repeat containing 34,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.7
ENSMUSG00000034973,DOPEY1,dopey family member 1,cellular_component|,transport|biological_process|protein transport|,molecular_function|,10,1.1,1.08,10,0,0,0,0,0,0.863,0,0,-0.6,2
ENSMUSG00000037649,H2-DMA,"histocompatibility 2, class II, locus DMa",intracellular|lysosome|lysosomal membrane|endosome|late endosome|multivesicular body|cell surface|endosome membrane|membrane|membrane|integral component of membrane|MHC class II protein complex|extracellular vesicular exosome|,immune system process|peptide antigen assembly with MHC class II protein complex|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|positive regulation of germinal center formation|positive regulation of humoral immune response|protein complex assembly|immune response|protein transport|immunoglobulin mediated immune response|antigen processing and presentation|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|antigen processing and presentation of exogenous peptide antigen via MHC class II|positive thymic T cell selection|positive regulation of T cell differentiation|inner ear development|positive regulation of immune response|chaperone mediated protein folding requiring cofactor|chaperone mediated protein folding requiring cofactor|,protein binding|MHC class II protein complex binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000054054,OLFR309,olfactory receptor 309,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.252,10,0,0,0,0,0,0.863,0,0,-1.8,1.4
ENSMUSG00000069044,USP9Y,"ubiquitin specific peptidase 9, Y chromosome",cellular_component|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.9,1
ENSMUSG00000038324,TRPC4AP,"transient receptor potential cation channel, subfamily C, member 4 associated protein",Cul4A-RING E3 ubiquitin ligase complex|,ubiquitin-dependent protein catabolic process|protein ubiquitination|,phosphatase binding|,10,0,0,10,0.2,0.111,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000090215,TRIM34B,tripartite motif-containing 34B,cellular_component|,biological_process|,molecular_function|metal ion binding|,9,1,0.395,9,0.1,0.105,0,0,0,0.863,0,0,-0.7,2
ENSMUSG00000044737,KLK14,kallikrein related-peptidase 14,extracellular region|extracellular space|extracellular vesicular exosome|,proteolysis|fertilization|negative regulation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|epidermis morphogenesis|seminal clot liquefaction|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.8,1.2
ENSMUSG00000001632,BRPF1,"bromodomain and PHD finger containing, 1",nucleus|MOZ/MORF histone acetyltransferase complex|,"histone H3 acetylation|positive regulation of transcription, DNA-templated|",metal ion binding|,9,-0.2,0.062,10,0.5,0.714,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000046168,KCNRG,potassium channel regulator,cellular_component|endoplasmic reticulum|,biological_process|protein homooligomerization|,identical protein binding|,10,-0.2,0.198,10,1,0.446,0,0,0,0.863,0,0,-0.8,2
ENSMUSG00000027517,ANKRD60,ankyrin repeat domain 60,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0555,10,-0.2,0.184,0,0,0,0.863,0,0,-1.7,1.2
ENSMUSG00000062995,ICA1,islet cell autoantigen 1,Golgi membrane|cytoplasm|Golgi apparatus|Golgi stack|cytosol|membrane|cell junction|dendrite|secretory granule membrane|synaptic vesicle membrane|cytoplasmic vesicle|synapse|perinuclear region of cytoplasm|,transport|neurotransmitter transport|regulation of protein homodimerization activity|regulation of neurotransmitter secretion|,protein domain specific binding|,10,0,0,10,-0.1,0.199,0,0,0,0.863,0,0,-2,0.7
ENSMUSG00000040455,USP45,ubiquitin specific petidase 45,cellular_component|,proteolysis|ubiquitin-dependent protein catabolic process|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.3
ENSMUSG00000060913,TRIM55,tripartite motif-containing 55,None,None,identical protein binding|identical protein binding|metal ion binding|,10,-0.1,0.0794,10,1,0.131,0,0,0,0.863,0,0,-1,2
ENSMUSG00000019189,RNF145,ring finger protein 145,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.1,0.16,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000048696,MEX3D,mex3 homolog D (C. elegans),nucleus|cytoplasm|perinuclear region of cytoplasm|,mRNA catabolic process|RNA destabilization|mRNA destabilization|,RNA binding|mRNA 3'-UTR binding|zinc ion binding|AU-rich element binding|poly(A) RNA binding|metal ion binding|,10,-0.1,0.159,10,0,0,0,0,0,0.863,0,0,-1.8,1.1
ENSMUSG00000027997,CASP6,caspase 6,nucleus|cytoplasm|cytoplasm|cytosol|,acute inflammatory response to non-antigenic stimulus|proteolysis|proteolysis|proteolysis|apoptotic process|response to glucose|response to iron ion|response to cytokine|response to hydrogen peroxide|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of retinal cell programmed cell death|,endopeptidase activity|cysteine-type endopeptidase activity|protein binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|identical protein binding|,10,0,0,10,-0.1,0.143,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000074892,B3GALT5,"UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.2,0.349,10,0,0,0,0,0,0.863,0,0,-1.7,1.3
ENSMUSG00000040883,TMEM205,transmembrane protein 205,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.9,1.1
ENSMUSG00000039497,DSE,dermatan sulfate epimerase,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,dermatan sulfate biosynthetic process|,isomerase activity|chondroitin-glucuronate 5-epimerase activity|,10,-0.1,0.116,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000037335,HAND1,heart and neural crest derivatives expressed transcript 1,nucleus|nucleus|nucleoplasm|nucleolus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|angiogenesis|in utero embryonic development|mesoderm formation|cell fate determination|heart looping|heart morphogenesis|heart morphogenesis|embryonic heart tube formation|cardiac left ventricle formation|cardiac right ventricle formation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|heart development|heart development|cell differentiation|embryonic heart tube development|odontogenesis of dentin-containing tooth|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|ventricular cardiac muscle tissue morphogenesis|ventricular cardiac muscle tissue morphogenesis|cardiac septum morphogenesis|mesenchyme development|cartilage morphogenesis|trophoblast giant cell differentiation|trophoblast giant cell differentiation|determination of heart left/right asymmetry|",DNA binding|transcription coactivator activity|transcription coactivator activity|protein binding|transcription factor binding|transcription factor binding|enzyme binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|bHLH transcription factor binding|bHLH transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|,10,0.1,0.111,10,-0.2,0.57,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000031494,CD209A,CD209a antigen,cell surface|membrane|integral component of membrane|,endocytosis|regulation of gene expression|regulation of blood coagulation|regulation of T cell proliferation|,mannose binding|carbohydrate binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000034892,RPS29,ribosomal protein S29,intracellular|cytoplasm|ribosome|small ribosomal subunit|cytosolic small ribosomal subunit|cytosolic small ribosomal subunit|ribonucleoprotein complex|extracellular vesicular exosome|,translation|,structural constituent of ribosome|structural constituent of ribosome|zinc ion binding|zinc ion binding|metal ion binding|,0,0,0,3,0,0,0,0,0,0.863,0,0,-1.8,2
ENSMUSG00000025401,MYO1A,myosin IA,cytoplasm|microvillus|microvillus|brush border|brush border|basal plasma membrane|actin cytoskeleton|basolateral plasma membrane|apical plasma membrane|lateral plasma membrane|lateral plasma membrane|myosin complex|growth cone|cortical actin cytoskeleton|cell leading edge|filamentous actin|neuron projection|neuronal cell body|membrane raft|,sensory perception of sound|cell projection organization|microvillus assembly|regulation of protein localization|vesicle localization|,nucleotide binding|motor activity|actin binding|calmodulin binding|ATP binding|,10,-0.1,0.129,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000061527,KRT5,keratin 5,nucleus|cytoplasm|mitochondrion|intermediate filament|plasma membrane|membrane|keratin filament|keratin filament|extracellular vesicular exosome|,None,structural molecule activity|protein binding|scaffold protein binding|,10,0.2,0.389,10,0,0,0,0,0,0.863,0,0,-2,1.1
ENSMUSG00000031204,ASB12,ankyrin repeat and SOCS box-containing 12,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0.1,0.159,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000027293,EHD4,EH-domain containing 4,endosome|endoplasmic reticulum|plasma membrane|membrane|membrane|perinuclear region of cytoplasm|recycling endosome membrane|extracellular vesicular exosome|,pinocytosis|regulation of endocytosis|endocytic recycling|positive regulation of peptidyl-tyrosine phosphorylation|protein homooligomerization|cellular response to growth factor stimulus|,nucleotide binding|GTPase activity|calcium ion binding|protein binding|ATP binding|GTP binding|metal ion binding|,8,0,0,8,-0.1,0.151,0,0,0,0.863,0,0,-1.6,1.6
ENSMUSG00000047414,FLRT2,fibronectin leucine rich transmembrane protein 2,extracellular space|membrane|integral component of membrane|extracellular vesicular exosome|,axon guidance|negative chemotaxis|regulation of neuron migration|,protein binding|chemorepellent activity|,10,0.1,0.175,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000028914,CASP9,caspase 9,intracellular|nucleus|nucleus|cytoplasm|mitochondrion|cytosol|cytosol|apoptosome|,proteolysis|proteolysis|proteolysis|apoptotic process|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|response to UV|response to organic cyclic compound|cellular response to UV|signal transduction in response to DNA damage|regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of neuron apoptotic process|cellular response to dexamethasone stimulus|regulation of response to DNA damage stimulus|,cysteine-type endopeptidase activity|protein binding|peptidase activity|peptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|SH3 domain binding|protein kinase binding|,10,0.1,0.0807,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000022019,TDRD3,tudor domain containing 3,nucleus|cytoplasm|exon-exon junction complex|,mRNA processing|chromatin modification|regulation of RNA biosynthetic process|,chromatin binding|transcription coactivator activity|RNA binding|methylated histone binding|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000023571,FAM132A,"family with sequence similarity 132, member A",extracellular region|extracellular region|extracellular space|,regulation of glucose metabolic process|positive regulation of insulin secretion involved in cellular response to glucose stimulus|negative regulation of gluconeogenesis|regulation of glucose import|positive regulation of glucose import|positive regulation of insulin receptor signaling pathway|negative regulation of inflammatory response|positive regulation of protein kinase B signaling|,hormone activity|,10,-0.6,1.56,10,0,0,0,0,0,0.863,0,0,-2,0.8
ENSMUSG00000026203,DNAJB2,"DnaJ (Hsp40) homolog, subfamily B, member 2",proteasome complex|nucleus|cytosol|inclusion body|,negative regulation of cell proliferation|negative regulation of cell growth|ER-associated ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|protein refolding|negative regulation of inclusion body assembly|negative regulation of protein deubiquitination|,Hsp70 protein binding|polyubiquitin binding|unfolded protein binding|chaperone binding|proteasome binding|,10,0.1,0.172,10,-0.8,2.38,0,0,0,0.863,0,0,-2,0.8
ENSMUSG00000027893,AHCYL1,S-adenosylhomocysteine hydrolase-like 1,intracellular|cell|endoplasmic reticulum|extracellular vesicular exosome|,mRNA polyadenylation|protein export from nucleus|one-carbon metabolic process|positive regulation of sodium ion transport|regulation of mRNA 3'-end processing|regulation of ion transmembrane transporter activity|regulation of anion transport|,adenosylhomocysteinase activity|protein binding|hydrolase activity|,10,-0.1,0.355,10,0,0,0,0,0,0.863,0,0,-2,1
ENSMUSG00000015668,PDZD11,PDZ domain containing 11,cytoplasm|cytosol|basolateral plasma membrane|,biological_process|,protein C-terminus binding|,10,0,0,10,0.3,0.681,0,0,0,0.863,0,0,-0.8,2
ENSMUSG00000022358,FBXO32,F-box protein 32,nucleus|nucleus|nucleolus|cytoplasm|Z disc|,response to electrical stimulus involved in regulation of muscle adaptation|muscle atrophy|response to denervation involved in regulation of muscle adaptation|cellular response to dexamethasone stimulus|,protein binding|,10,-0.2,0.681,10,0,0,0,0,0,0.863,0,0,-1.5,1.4
ENSMUSG00000018340,ANXA6,annexin A6,cytoplasm|lysosomal membrane|membrane|apical plasma membrane|late endosome membrane|protein complex|perinuclear region of cytoplasm|extracellular vesicular exosome|,calcium ion transport|regulation of muscle contraction|ion transmembrane transport|protein homooligomerization|,calcium ion binding|GTP binding|calcium-dependent phospholipid binding|lipid binding|ligand-gated ion channel activity|cholesterol binding|protein homodimerization activity|calcium-dependent protein binding|,10,0,0,10,0.5,0.978,0,0,0,0.863,0,0,-1.9,1.3
ENSMUSG00000024168,TMEM204,transmembrane protein 204,plasma membrane|membrane|integral component of membrane|cell junction|,lymph vessel development|lymph vessel development|regulation of vascular endothelial growth factor receptor signaling pathway|smooth muscle cell differentiation|,protein binding|,10,0.1,0.056,10,-0.1,0.089,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000010830,KDELR3,KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,protein retention in ER lumen|transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|ER retention sequence binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000002064,SDF2,stromal cell derived factor 2,extracellular region|membrane|,None,None,10,0.2,0.82,10,0,0,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000030340,SCNN1A,"sodium channel, nonvoltage-gated 1 alpha",cytosol|plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|apical plasma membrane|cortical actin cytoskeleton|motile cilium|sodium channel complex|sodium channel complex|cell projection|ciliary membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|sodium ion transport|sodium ion transport|sodium ion transmembrane transport|sodium ion transmembrane transport|regulation of body fluid levels|multicellular organismal water homeostasis|response to stimulus|sensory perception of taste|sodium ion homeostasis|,actin binding|sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|ligand-gated sodium channel activity|WW domain binding|WW domain binding|,10,-0.2,0.168,10,0.2,0.708,0,0,0,0.863,0,0,-0.9,2
ENSMUSG00000051956,RNF133,ring finger protein 133,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,protein autoubiquitination|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0.1,0.0884,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000048402,GLI2,GLI-Kruppel family member GLI2,nucleus|nucleus|cytoplasm|cytoplasm|cilium|membrane|nuclear speck|motile primary cilium|primary cilium|ciliary tip|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|skeletal system development|osteoblast differentiation|osteoblast differentiation|in utero embryonic development|kidney development|morphogenesis of an epithelium|chondrocyte differentiation|osteoblast development|osteoblast development|transcription, DNA-templated|regulation of transcription, DNA-templated|smoothened signaling pathway|smoothened signaling pathway|smoothened signaling pathway|pattern specification process|pattern specification process|axon guidance|ventral midline development|ventral midline development|hindgut morphogenesis|hindgut morphogenesis|heart development|cell proliferation|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of smoothened signaling pathway|epidermal cell differentiation|dorsal/ventral pattern formation|proximal/distal pattern formation|floor plate formation|spinal cord dorsal/ventral patterning|spinal cord dorsal/ventral patterning|ventral spinal cord development|spinal cord motor neuron differentiation|cerebellar cortex morphogenesis|cerebellar cortex morphogenesis|smoothened signaling pathway involved in ventral spinal cord interneuron specification|smoothened signaling pathway involved in spinal cord motor neuron cell fate specification|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|neural tube development|smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation|smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation|spinal cord ventral commissure morphogenesis|pituitary gland development|cell differentiation|lung development|lung development|mammary gland development|hindbrain development|hindbrain development|negative regulation of chondrocyte differentiation|tube development|odontogenesis of dentin-containing tooth|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|positive regulation of neuron differentiation|positive regulation of DNA replication|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic digestive tract development|developmental growth|anatomical structure formation involved in morphogenesis|neuron development|branching morphogenesis of an epithelial tube|anatomical structure development|anatomical structure development|notochord regression|head development|prostatic bud formation|mammary gland duct morphogenesis|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|cellular response to organic cyclic compound|cochlea morphogenesis|",nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,9,0.1,0.206,9,-0.4,1.37,0,0,0,0.863,0,0,-1.9,1.1
ENSMUSG00000040812,AGBL2,ATP/GTP binding protein-like 2,cytoplasm|cytosol|,proteolysis|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.0296,10,-0.9,0.774,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000024644,CNDP2,CNDP dipeptidase 2 (metallopeptidase M20 family),cytoplasm|cytosol|extracellular vesicular exosome|,proteolysis|proteolysis|metabolic process|,carboxypeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|dipeptidase activity|dipeptidase activity|tripeptidase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.8,1.3
ENSMUSG00000029060,MIB2,mindbomb homolog 2 (Drosophila),ubiquitin ligase complex|cytoplasm|endosome|early endosome|,signal transduction|Notch signaling pathway|protein ubiquitination|positive regulation of I-kappaB kinase/NF-kappaB signaling|,"actin binding|ubiquitin-protein transferase activity|signal transducer activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,0.568,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000067215,USP51,ubiquitin specific protease 51,cellular_component|,proteolysis|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|,10,-1.3,1.89,10,0,0,0,0,0,0.863,0,0,-2,1
ENSMUSG00000046282,ADAM20,a disintegrin and metallopeptidase domain 20,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.134,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000079259,TRIM71,tripartite motif-containing 71,cytoplasmic mRNA processing body|intracellular|cytoplasm|,G1/S transition of mitotic cell cycle|neural tube closure|multicellular organismal development|fibroblast growth factor receptor signaling pathway|miRNA metabolic process|neural tube development|gene silencing by RNA|negative regulation of translation involved in gene silencing by miRNA|regulation of protein metabolic process|protein autoubiquitination|regulation of gene silencing by miRNA|regulation of gene silencing by miRNA|cellular response to organic substance|stem cell proliferation|regulation of neural precursor cell proliferation|positive regulation of gene silencing by miRNA|positive regulation of gene silencing by miRNA|,"RNA binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|miRNA binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000046834,KRT1,keratin 1,extracellular space|nucleus|intermediate filament|plasma membrane|membrane|keratin filament|extracellular vesicular exosome|blood microparticle|,"complement activation, lectin pathway|negative regulation of inflammatory response|negative regulation of inflammatory response|establishment of skin barrier|",structural molecule activity|carbohydrate binding|,10,-0.1,0.133,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000014232,CLUAP1,clusterin associated protein 1,intracellular|cell|nucleus|centrosome|cilium|cilium|axoneme|intraciliary transport particle B|cell projection|intracellular membrane-bounded organelle|ciliary tip|ciliary base|,neural tube closure|heart looping|smoothened signaling pathway|smoothened signaling pathway|floor plate formation|cell projection organization|axoneme assembly|intraciliary transport|cilium assembly|left/right pattern formation|,molecular_function|,6,0.1,0.0719,6,0,0,0,0,0,0.863,0,0,-1.6,1.8
ENSMUSG00000028405,ACO1,aconitase 1,cytoplasm|cytoplasm|mitochondrion|mitochondrion|endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|intracellular membrane-bounded organelle|extracellular vesicular exosome|,tricarboxylic acid cycle|citrate metabolic process|regulation of translation|cellular iron ion homeostasis|cellular iron ion homeostasis|cellular iron ion homeostasis|metabolic process|post-embryonic development|response to iron(II) ion|regulation of gene expression|intestinal absorption|,"RNA binding|aconitate hydratase activity|aconitate hydratase activity|lyase activity|iron-responsive element binding|iron-responsive element binding|metal ion binding|mRNA 5'-UTR binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,0,0,10,-0.7,0.256,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000030638,SH3GL3,SH3-domain GRB2-like 3,cytoplasm|endosome|membrane|extracellular vesicular exosome|,endocytosis|,protein binding|lipid binding|identical protein binding|,10,0,0,10,0.2,0.12,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000009575,CBX5,chromobox 5,"histone deacetylase complex|chromosome, centromeric region|kinetochore|heterochromatin|nucleus|nucleus|chromosome|nuclear heterochromatin|nucleolus|nucleolus|chromocenter|PML body|transcriptional repressor complex|histone methyltransferase complex|","negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|","chromatin binding|protein binding|protein binding, bridging|methylated histone binding|protein homodimerization activity|histone deacetylase binding|repressing transcription factor binding|",10,0,0,10,0.1,0.083,0,0,0,0.863,0,0,-2,1
ENSMUSG00000025353,ORMDL2,ORM1-like 2 (S. cerevisiae),endoplasmic reticulum|membrane|integral component of membrane|,ceramide metabolic process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000019935,SLC17A8,"solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8",membrane|integral component of membrane|cell junction|synaptic vesicle membrane|cytoplasmic vesicle|neuron projection|synapse|,transport|ion transport|sodium ion transport|neurotransmitter transport|sensory perception of sound|L-glutamate transport|transmembrane transport|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|symporter activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000025993,SLC40A1,"solute carrier family 40 (iron-regulated transporter), member 1",intracellular|multivesicular body|plasma membrane|plasma membrane|synaptic vesicle|membrane|integral component of membrane|basolateral plasma membrane|,lymphocyte homeostasis|endothelium development|transport|ion transport|iron ion transport|cellular iron ion homeostasis|regulation of transcription from RNA polymerase II promoter in response to iron|iron ion transmembrane transport|iron ion transmembrane transport|negative regulation of apoptotic process|spleen development|iron ion homeostasis|spleen trabecula formation|multicellular organismal iron ion homeostasis|,iron ion transmembrane transporter activity|iron ion transmembrane transporter activity|protein binding|,10,0,0,10,-0.1,0.081,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000033805,EPHX4,epoxide hydrolase 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|catalytic activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000014852,ADAMTS13,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13",extracellular region|proteinaceous extracellular matrix|extracellular space|,proteolysis|proteolysis|proteolysis|blood coagulation|hemostasis|peptide catabolic process|,endopeptidase activity|endopeptidase activity|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,9,0,0,9,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000031812,MAP1LC3B,microtubule-associated protein 1 light chain 3 beta,autophagic vacuole membrane|intracellular|cytoplasm|autophagic vacuole|cytoskeleton|microtubule|microtubule associated complex|axoneme|membrane|axon|dendrite|cytoplasmic vesicle|neuronal cell body|,autophagy|positive regulation of protein binding|positive regulation of mucus secretion|,protein binding|microtubule binding|tubulin binding|protein domain specific binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000026933,CAMSAP1,calmodulin regulated spectrin-associated protein 1,cytoplasm|cytoskeleton|microtubule|,cytoskeleton organization|regulation of cell morphogenesis|neuron projection development|,calmodulin binding|microtubule binding|spectrin binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.8
ENSMUSG00000026577,BLZF1,basic leucine zipper nuclear factor 1,Golgi membrane|nucleus|cytoplasm|Golgi apparatus|,transport|Golgi organization|protein transport|vesicle-mediated transport|Golgi to plasma membrane protein transport|,protein binding|enzyme binding|ubiquitin protein ligase binding|,10,0.2,0.575,10,0,0,0,0,0,0.863,0,0,-1.3,1.6
ENSMUSG00000038997,ASB17,ankyrin repeat and SOCS box-containing 17,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,-0.1,0.552,10,0.2,0.41,0,0,0,0.863,0,0,-1.1,1.8
ENSMUSG00000053856,DNAJC5G,"DnaJ (Hsp40) homolog, subfamily C, member 5 gamma",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.107,10,0,0,0,0,0,0.863,0,0,-1.8,1.4
ENSMUSG00000038828,TMEM214,transmembrane protein 214,endoplasmic reticulum|cytoplasmic microtubule|membrane|integral component of membrane|,apoptotic process|biological_process|,molecular_function|,10,-0.2,0.356,10,0.2,0.505,0,0,0,0.863,0,0,-1.5,1.4
ENSMUSG00000037129,TMPRSS13,"transmembrane protease, serine 13",membrane|integral component of membrane|blood microparticle|,proteolysis|biological_process|,molecular_function|catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.3,1.48,10,0.1,0.0884,0,0,0,0.863,0,0,-1.8,1
ENSMUSG00000039470,ZDHHC2,"zinc finger, DHHC domain containing 2",endoplasmic reticulum|Golgi apparatus|integral component of plasma membrane|membrane|integral component of membrane|recycling endosome membrane|,protein palmitoylation|protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000040722,SCAMP5,secretory carrier membrane protein 5,Golgi membrane|endosome|Golgi apparatus|plasma membrane|synaptic vesicle|synaptic vesicle|membrane|integral component of membrane|cell junction|SNARE complex|cytoplasmic vesicle|trans-Golgi network membrane|synapse|recycling endosome membrane|,transport|exocytosis|protein transport|response to endoplasmic reticulum stress|negative regulation of endocytosis|positive regulation of calcium ion-dependent exocytosis|positive regulation of cytokine secretion|,molecular_function|,10,0,0,10,0.2,0.388,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000002910,ARRDC2,arrestin domain containing 2,plasma membrane|cytoplasmic vesicle|,signal transduction|biological_process|,molecular_function|,10,0,0,10,-0.2,0.286,0,0,0,0.863,0,0,-1.3,1.6
ENSMUSG00000061536,SEC22C,SEC22 vesicle trafficking protein homolog C (S. cerevisiae),endoplasmic reticulum|membrane|integral component of membrane|,transport|protein transport|vesicle-mediated transport|,None,10,-0.3,0.522,10,0.1,0.132,0,0,0,0.863,0,0,-1,2
ENSMUSG00000030605,MFGE8,milk fat globule-EGF factor 8 protein,extracellular region|extracellular space|extracellular space|external side of plasma membrane|membrane|membrane|extrinsic component of plasma membrane|extracellular matrix|extracellular vesicular exosome|,"angiogenesis|phagocytosis, recognition|phagocytosis, engulfment|cell adhesion|single fertilization|positive regulation of phagocytosis|positive regulation of apoptotic cell clearance|",phosphatidylserine binding|integrin binding|phosphatidylethanolamine binding|,10,-0.1,0.232,10,0.1,0.031,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000044164,RNF182,ring finger protein 182,cytoplasm|membrane|integral component of membrane|,protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.2,0.0826,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000038822,HACE1,"HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1",Golgi membrane|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Golgi organization|cell cycle|protein ubiquitination|regulation of cell migration|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|membrane fusion|protein K48-linked ubiquitination|","ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|Rab GTPase binding|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|Rac GTPase binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.7,1.3,10,0.1,0.129,0,0,0,0.863,0,0,-1.9,1
ENSMUSG00000026179,PNKD,paroxysmal nonkinesiogenic dyskinesia,nucleus|cytoplasm|mitochondrion|mitochondrion|membrane|,"glutathione biosynthetic process|regulation of synaptic transmission, dopaminergic|regulation of dopamine metabolic process|neuromuscular process controlling posture|",molecular_function|GPI-anchor transamidase activity|hydroxyacylglutathione hydrolase activity|zinc ion binding|hydrolase activity|metal ion binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,-0.1,0.0213,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000075502,ZBTBD6,kelch repeat and BTB (POZ) domain containing 6,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.732,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000029420,RIMBP2,RIMS binding protein 2,plasma membrane|membrane|cell junction|synapse|,negative regulation of phosphatase activity|,None,10,0.1,0.0378,10,0,0,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000068923,SYT11,synaptotagmin XI,integral component of plasma membrane|synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,transport|,transporter activity|calcium ion binding|calcium-dependent phospholipid binding|metal ion binding|,10,-0.2,0.724,10,0.1,0.193,0,0,0,0.863,0,0,-1.4,1.5
ENSMUSG00000027660,SKIL,SKI-like,acrosomal vesicle|nucleus|nucleus|cytoplasm|cytoplasm|PML body|protein complex|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|blastocyst formation|lymphocyte homeostasis|cell cycle arrest|transforming growth factor beta receptor signaling pathway|skeletal muscle tissue development|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of cell differentiation|positive regulation of axonogenesis|protein homotrimerization|protein heterotrimerization|lens fiber cell differentiation|response to growth factor|positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage|,chromatin binding|transcription corepressor activity|protein binding|protein domain specific binding|protein complex binding|SMAD binding|SMAD binding|,10,0,0,10,-0.9,0.627,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000027412,LPIN3,lipin 3,nucleus|,lipid metabolic process|fatty acid metabolic process|dephosphorylation|,phosphatidate phosphatase activity|hydrolase activity|,10,0,0,10,0.1,0.156,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000075702,SELM,selenoprotein M,cell|cytoplasm|endoplasmic reticulum|Golgi apparatus|,response to selenium ion|multicellular organism growth|corticosterone secretion|hormone metabolic process|adipose tissue development|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.9,1.2
ENSMUSG00000044469,TNFAIP8L1,"tumor necrosis factor, alpha-induced protein 8-like 1",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.097,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000072419,DPPA2,developmental pluripotency associated 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|stem cell maintenance|regulation of histone methylation|lung-associated mesenchyme development|lung-associated mesenchyme development|positive regulation of stem cell proliferation|",nucleic acid binding|chromatin binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000001827,FOLR1,folate receptor 1 (adult),extracellular region|intracellular|cell|endosome|plasma membrane|brush border|membrane|anchored component of membrane|anchored component of external side of plasma membrane|cytoplasmic vesicle|brush border membrane|anchored component of plasma membrane|extracellular vesicular exosome|,posttranslational protein targeting to membrane|transport|folic acid transport|folic acid transport|folic acid metabolic process|,receptor activity|folic acid binding|folic acid binding|folic acid transporter activity|folic acid transporter activity|,10,0,0,10,0.1,0.142,0,0,0,0.863,0,0,-1.8,1.4
ENSMUSG00000020476,DBNL,drebrin-like,ruffle|podosome|intracellular|cytoplasm|Golgi apparatus|cytoskeleton|plasma membrane|cell cortex|postsynaptic density|membrane|lamellipodium|cell junction|dendrite|cytoplasmic vesicle|cell projection|synapse|extracellular vesicular exosome|,immune system process|transport|endocytosis|synapse assembly|Rac protein signal transduction|neuron projection morphogenesis|podosome assembly|,actin binding|protein binding|protein C-terminus binding|protein domain specific binding|actin filament binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000023286,UBE2J2,ubiquitin-conjugating enzyme E2J 2,endoplasmic reticulum|membrane|integral component of membrane|,response to unfolded protein|,nucleotide binding|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000035104,EVA1A,eva-1 homolog A (C. elegans),lysosome|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,autophagy|apoptotic process|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000045078,RNF216,ring finger protein 216,nucleus|cytoplasm|,apoptotic process|regulation of interferon-beta production|proteasome-mediated ubiquitin-dependent protein catabolic process|regulation of defense response to virus by host|protein K48-linked ubiquitination|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.265,10,0,0,0,0,0,0.863,0,0,-1.1,1.9
ENSMUSG00000054999,NAALADL1,N-acetylated alpha-linked acidic dipeptidase-like 1,cellular_component|plasma membrane|membrane|integral component of membrane|,proteolysis|biological_process|metabolic process|,molecular_function|catalytic activity|carboxypeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|dipeptidase activity|metal ion binding|,10,0,0,10,-0.1,0.123,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000029312,KLHL8,kelch-like 8,nucleus|Cul3-RING ubiquitin ligase complex|,protein ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,molecular_function|,10,0,0,10,-0.1,0.0375,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000025050,PCGF6,polycomb group ring finger 6,nucleus|nucleus|PcG protein complex|PRC1 complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-templated|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding|protein domain specific binding|metal ion binding|,9,0,0,9,0,0,0,0,0,0.863,0,0,-1.2,1.9
ENSMUSG00000027274,MKKS,McKusick-Kaufman syndrome,intracellular|cytoplasm|centrosome|cytoskeleton|motile cilium|,protein folding|spermatid development|sensory perception of smell|negative regulation of gene expression|artery smooth muscle contraction|striatum development|hippocampus development|cerebral cortex development|leptin-mediated signaling pathway|nonmotile primary cilium assembly|nonmotile primary cilium assembly|social behavior|negative regulation of appetite by leptin-mediated signaling pathway|positive regulation of multicellular organism growth|vasodilation|cilium assembly|cellular protein metabolic process|response to leptin|photoreceptor cell maintenance|negative regulation of blood pressure|brain morphogenesis|detection of mechanical stimulus involved in sensory perception of sound|chaperone-mediated protein complex assembly|cartilage development|cilium morphogenesis|regulation of cilium beat frequency involved in ciliary motility|,nucleotide binding|RNA polymerase II repressing transcription factor binding|ATP binding|unfolded protein binding|,10,-0.2,0.415,10,0,0,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000033208,S100B,"S100 protein, beta polypeptide, neural",ruffle|extracellular region|extracellular space|nucleus|nucleus|cytoplasm|cytoplasm|neuronal cell body|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,energy reserve metabolic process|cellular calcium ion homeostasis|learning or memory|memory|positive regulation of cell proliferation|regulation of cell shape|regulation of cytokine biosynthetic process|positive regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|regulation of neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|positive regulation of synaptic transmission|negative regulation of skeletal muscle cell differentiation|,receptor binding|calcium ion binding|calcium ion binding|zinc ion binding|identical protein binding|protein homodimerization activity|S100 protein binding|metal ion binding|calcium-dependent protein binding|RAGE receptor binding|,10,0,0,10,0.1,0.0522,0,0,0,0.863,0,0,-1.3,1.6
ENSMUSG00000035770,DYNC1LI2,"dynein, cytoplasmic 1 light intermediate chain 2",cytoplasm|centrosome|cytoskeleton|cytoplasmic dynein complex|microtubule|membrane|dynein complex|,microtubule cytoskeleton organization|transport|microtubule-based movement|centrosome localization|,nucleotide binding|motor activity|microtubule motor activity|protein binding|ATP binding|,10,-0.1,0.0844,10,0,0,0,0,0,0.863,0,0,-2,1
ENSMUSG00000027744,STOML3,stomatin (Epb7.2)-like 3,plasma membrane|cilium|membrane|integral component of membrane|membrane raft|,signal transduction|,protein binding|,10,-0.3,1.49,10,0,0,0,0,0,0.863,0,0,-1.5,1.4
ENSMUSG00000046312,AI464131,expressed sequence AI464131,membrane|integral component of membrane|nuclear membrane|,carbohydrate metabolic process|metabolic process|positive regulation of insulin-like growth factor receptor signaling pathway|skeletal muscle fiber development|positive regulation of protein kinase B signaling|,"catalytic activity|hydrolase activity, hydrolyzing O-glycosyl compounds|protein binding|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,-0.2,0.527,10,0.1,0.0013,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000031749,ST3GAL2,"ST3 beta-galactoside alpha-2,3-sialyltransferase 2",extracellular region|Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|protein glycosylation|sialylation|sialylation|,"beta-galactoside (CMP) alpha-2,3-sialyltransferase activity|sialyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,10,-0.1,0.147,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000021589,RHOBTB3,Rho-related BTB domain containing 3,intracellular|cell|cytoplasm|Golgi apparatus|,"ATP catabolic process|transport|small GTPase mediated signal transduction|retrograde transport, endosome to Golgi|","nucleotide binding|thiamine-pyrophosphatase activity|protein binding|ATP binding|GTP binding|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|ATPase activity|Rab GTPase binding|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|",10,0,0,10,-1.4,3.11,0,0,0,0.863,0,0,-3,0.4
ENSMUSG00000034930,RTKN,rhotekin,intracellular|,apoptotic process|signal transduction|Rho protein signal transduction|negative regulation of catalytic activity|negative regulation of catalytic activity|,nucleotide binding|GTPase inhibitor activity|GTPase inhibitor activity|protein binding|GTP binding|Rho GTPase binding|GTP-Rho binding|GTP-Rho binding|,10,0.1,0.135,10,-0.1,0.112,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000046523,KCTD4,potassium channel tetramerisation domain containing 4,cellular_component|,biological_process|protein homooligomerization|,molecular_function|,9,0,0,9,-0.1,0.202,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000072244,TRIM6,tripartite motif-containing 6,intracellular|cytoplasm|cytoplasm|,protein trimerization|,protein binding|zinc ion binding|metal ion binding|,10,0.9,0.427,10,0,0,0,0,0,0.863,0,0,-1.6,1.8
ENSMUSG00000037025,FOXA2,forkhead box A2,nucleus|nucleus|cytoplasm|,"positive regulation of transcription from RNA polymerase II promoter by glucose|negative regulation of transcription from RNA polymerase II promoter by glucose|in utero embryonic development|ectoderm formation|cell fate specification|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|pattern specification process|adult locomotory behavior|anatomical structure morphogenesis|anterior/posterior pattern specification|dorsal/ventral pattern formation|regulation of gene expression|negative regulation of epithelial to mesenchymal transition|chromatin modification|regulation of lipid metabolic process|regulation of lipid metabolic process|regulation of steroid metabolic process|regulation of steroid metabolic process|cell differentiation in hindbrain|cell differentiation in hindbrain|dorsal/ventral neural tube patterning|dorsal/ventral neural tube patterning|signal transduction involved in regulation of gene expression|regulation of blood coagulation|lung development|endocrine pancreas development|endocrine pancreas development|somite rostral/caudal axis specification|negative regulation of glucokinase activity|positive regulation of embryonic development|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of smoothened signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase III promoter|cell development|anatomical structure formation involved in morphogenesis|neuron fate specification|neuron fate specification|epithelial tube branching involved in lung morphogenesis|lung epithelial cell differentiation|regulation of insulin secretion involved in cellular response to glucose stimulus|connective tissue development|response to interleukin-6|dopaminergic neuron differentiation|primitive streak formation|positive regulation of gastrulation|negative regulation of detection of glucose|regulation of transcription from RNA polymerase II promoter involved in detection of glucose|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|kinase binding|protein domain specific binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|SMAD binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.8
ENSMUSG00000049580,TSKU,tsukushi,extracellular region|extracellular space|,regulation of gene expression|corpus callosum morphogenesis|lateral ventricle development|anterior commissure morphogenesis|negative regulation of Wnt signaling pathway|camera-type eye development|ciliary body morphogenesis|,protein binding|,10,-0.2,0.349,10,0.1,0.302,0,0,0,0.863,0,0,-1.4,1.5
ENSMUSG00000032182,YIPF2,"Yip1 domain family, member 2",membrane|integral component of membrane|transport vesicle|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000024248,COX7A2L,cytochrome c oxidase subunit VIIa polypeptide 2-like,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain|membrane|,None,cytochrome-c oxidase activity|electron carrier activity|,10,-0.5,0.669,10,0,0,0,0,0,0.863,0,0,-2,1
ENSMUSG00000048163,SELPLG,"selectin, platelet (p-selectin) ligand",plasma membrane|membrane|integral component of membrane|,cell adhesion|leukocyte tethering or rolling|leukocyte adhesive activation|,protein binding|,10,-0.4,1.55,10,0.1,0.0583,0,0,0,0.863,0,0,-1.8,1
ENSMUSG00000029236,NMU,neuromedin U,extracellular region|terminal bouton|,gastric acid secretion|regulation of smooth muscle contraction|neuropeptide signaling pathway|sensory perception of pain|eating behavior|positive regulation of smooth muscle contraction|positive regulation of hormone secretion|positive regulation of synaptic transmission|,neuromedin U receptor binding|,10,1,0.75,10,0,0,0,0,0,0.863,0,0,-0.8,2
ENSMUSG00000019790,STXBP5,syntaxin binding protein 5 (tomosyn),cytoplasm|plasma membrane|acetylcholine-gated channel complex|membrane|integral component of membrane|secretory granule|,transport|exocytosis|axonogenesis|regulation of gene expression|protein transport|vesicle-mediated transport|regulation of exocytosis|regulation of blood coagulation|positive regulation of exocytosis|,protein binding|syntaxin-1 binding|syntaxin-1 binding|syntaxin-1 binding|syntaxin binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.1,1.9
ENSMUSG00000092035,PEG10,paternally expressed 10,nucleus|cytoplasm|,placenta development|apoptotic process|cell differentiation|negative regulation of transforming growth factor beta receptor signaling pathway|,nucleic acid binding|DNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,-0.1,0.0461,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000020473,AEBP1,AE binding protein 1,extracellular region|extracellular space|nucleus|cytoplasm|extracellular matrix|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|proteolysis|cell adhesion|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|transcription corepressor activity|carboxypeptidase activity|metallocarboxypeptidase activity|calmodulin binding|zinc ion binding|,10,0.1,0.0226,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000015441,GZMF,granzyme F,membrane|,cytolysis|,catalytic activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.1,0.121,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000043468,ADAM30,a disintegrin and metallopeptidase domain 30,cellular_component|,proteolysis|integrin-mediated signaling pathway|biological_process|,molecular_function|peptidase activity|metallopeptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.6
ENSMUSG00000090799,KLHL33,kelch-like 33,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0689,10,0,0,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000021795,SFTPD,surfactant associated protein D,extracellular region|proteinaceous extracellular matrix|collagen trimer|extracellular space|cytoplasm|multivesicular body|rough endoplasmic reticulum|cytoplasmic vesicle|,immune system process|respiratory gaseous exchange|opsonization|negative regulation of interleukin-2 production|negative regulation of T cell proliferation|surfactant homeostasis|innate immune response|lung alveolus development|negative regulation of phagocytosis|positive regulation of phagocytosis|regulation of liquid surface tension|,lipopolysaccharide binding|carbohydrate binding|identical protein binding|monosaccharide binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000035649,ZCCHC7,"zinc finger, CCHC domain containing 7",nucleus|nucleolus|cytoplasm|,biological_process|,nucleic acid binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.1,0.332,10,0.3,0.462,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000030882,DNHD1,dynein heavy chain domain 1,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.3,0.156,10,0,0,0,0,0,0.863,0,0,-1.7,1.2
ENSMUSG00000052584,SERP2,stress-associated endoplasmic reticulum protein family member 2,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,transport|protein transport|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000031545,AGPAT6,"1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)",endoplasmic reticulum|endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,glandular epithelial cell maturation|lipid metabolic process|fatty acid metabolic process|acyl-CoA metabolic process|triglyceride metabolic process|phosphatidylcholine biosynthetic process|lactation|metabolic process|lipid biosynthetic process|phospholipid biosynthetic process|triglyceride biosynthetic process|mammary gland development|regulation of multicellular organism growth|diacylglycerol metabolic process|,"glycerol-3-phosphate O-acyltransferase activity|glycerol-3-phosphate O-acyltransferase activity|glycerol-3-phosphate O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0,0,10,-0.9,1.36,0,0,0,0.863,0,0,-2,0.6
ENSMUSG00000022322,SHCBP1,Shc SH2-domain binding protein 1,cellular_component|,fibroblast growth factor receptor signaling pathway|regulation of neural precursor cell proliferation|,protein binding|SH2 domain binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000066357,WDR6,WD repeat domain 6,cytoplasm|plasma membrane|COP9 signalosome|protein complex|,cell cycle|cell cycle arrest|negative regulation of cell proliferation|negative regulation of autophagy|,insulin receptor substrate binding|poly(A) RNA binding|,10,0,0,10,0.1,0.00508,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000036834,PLCH1,"phospholipase C, eta 1",cytoplasm|cytosol|membrane|,lipid metabolic process|signal transduction|lipid catabolic process|intracellular signal transduction|phosphatidylinositol-mediated signaling|,phosphatidylinositol phospholipase C activity|signal transducer activity|calcium ion binding|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|calcium-dependent phospholipase C activity|,10,0.1,0.000934,10,0,0,0,0,0,0.863,0,0,-1.9,1.1
ENSMUSG00000043274,OLFR1123,olfactory receptor 1123,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.209,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000062444,AP3B2,"adaptor-related protein complex 3, beta 2 subunit",intracellular|cell|nucleus|cytoplasm|Golgi apparatus|trans-Golgi network|membrane|membrane coat|AP-3 adaptor complex|cytoplasmic vesicle|,transport|intracellular protein transport|anterograde axon cargo transport|protein transport|vesicle-mediated transport|anterograde synaptic vesicle transport|,None,10,0.4,1.17,10,-0.2,0.423,0,0,0,0.863,0,0,-1.3,1.8
ENSMUSG00000020537,DRG2,developmentally regulated GTP binding protein 2,cytoplasm|mitochondrion|membrane|,biological_process|,nucleotide binding|GTP binding|,10,-0.1,0.0128,10,-1,0.683,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000014542,CLEC4F,"C-type lectin domain family 4, member f",plasma membrane|membrane|integral component of membrane|,endocytosis|NK T cell activation|,galactose binding|carbohydrate binding|glycolipid binding|,10,0,0,10,-1.3,2.41,0,0,0,0.863,0,0,-2,0.5
ENSMUSG00000042251,PM20D1,peptidase M20 domain containing 1,extracellular region|extracellular vesicular exosome|,proteolysis|metabolic process|regulation of defense response to virus by host|regulation of viral process|negative regulation of neuron death|,peptidase activity|hydrolase activity|metal ion binding|,10,-0.2,0.585,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000034768,ASB16,ankyrin repeat and SOCS box-containing 16,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,-0.3,0.788,10,0,0,0,0,0,0.863,0,0,-1.7,1.2
ENSMUSG00000028344,INVS,inversin,nucleus|cytoplasm|cytoskeleton|microtubule|membrane|,kidney development|multicellular organismal development|post-embryonic development|Wnt signaling pathway|pancreas development|organ development|embryonic heart tube left/right pattern formation|negative regulation of canonical Wnt signaling pathway|,protein binding|calmodulin binding|,10,1.3,1.85,10,0,0,0,0,0,0.863,0,0,-0.8,2
ENSMUSG00000026455,KLHL12,kelch-like 12,Golgi membrane|ER to Golgi transport vesicle|cytoplasmic vesicle|Cul3-RING ubiquitin ligase complex|,protein monoubiquitination|transport|ER to Golgi vesicle-mediated transport|Wnt signaling pathway|vesicle-mediated transport|COPII vesicle coating|,molecular_function|,9,0,0,9,0.4,0.469,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000038485,SOCS7,suppressor of cytokine signaling 7,nucleus|nucleolus|cytoplasm|plasma membrane|membrane|intracellular membrane-bounded organelle|,insulin receptor signaling pathway|negative regulation of signal transduction|protein ubiquitination|intracellular signal transduction|regulation of growth|fat cell differentiation|,None,10,0.2,0.0697,10,-0.3,0.645,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000054659,PM20D2,peptidase M20 domain containing 2,nucleus|extracellular vesicular exosome|,biological_process|,hydrolase activity|,10,-0.1,0.136,10,0.1,0.373,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000027978,PRSS12,"protease, serine 12 neurotrypsin (motopsin)",extracellular region|plasma membrane|membrane|axon|dendrite|cytoplasmic vesicle|synaptic cleft|terminal bouton|synapse|,proteolysis|proteolysis|exocytosis|zymogen activation|,catalytic activity|serine-type endopeptidase activity|scavenger receptor activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.284,10,-0.1,0.0422,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000034145,TMEM63C,transmembrane protein 63c,cellular_component|membrane|integral component of membrane|,transport|ion transport|cation transport|ion transmembrane transport|,calcium activated cation channel activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000032002,DCUN1D5,"DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.8,1.37,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000028015,CTSO,cathepsin O,cellular_component|lysosome|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.1,0.0611,10,0,0,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000038135,CRYGN,"crystallin, gamma N",cellular_component|,biological_process|,molecular_function|structural constituent of eye lens|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000064023,KLK8,kallikrein related-peptidase 8,extracellular region|extracellular space|cytoplasm|cytoplasm|,proteolysis|memory|cell death|response to wounding|negative regulation of myelination|keratinocyte proliferation|negative regulation of axon regeneration|neuron projection morphogenesis|regulation of synapse organization|synapse organization|,catalytic activity|serine-type endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,0,0,10,-0.8,0.993,0,0,0,0.863,0,0,-2,1
ENSMUSG00000037348,PAQR7,progestin and adipoQ receptor family member VII,plasma membrane|membrane|integral component of membrane|,multicellular organismal development|cell differentiation|steroid hormone mediated signaling pathway|oogenesis|response to steroid hormone|,steroid hormone receptor activity|steroid binding|lipid binding|,10,0.2,0.543,10,0,0,0,0,0,0.863,0,0,-1.8,1.2
ENSMUSG00000054083,CAPN12,calpain 12,intracellular|cytoplasm|,proteolysis|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|metal ion binding|,9,0,0,9,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000017309,CD300LG,CD300 antigen like family member G,endosome|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|extracellular vesicular exosome|,immune system process|immunoglobulin transcytosis in epithelial cells|,IgM binding|,10,0.1,0.0189,10,-0.1,0.323,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000056596,TRNP1,TMF1-regulated nuclear protein 1,nucleus|nuclear euchromatin|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|multicellular organismal development|nervous system development|cerebellar cortex morphogenesis|regulation of cell proliferation|regulation of cell cycle|neural precursor cell proliferation|",DNA binding|protein binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-2,1.1
ENSMUSG00000031389,ARHGAP4,Rho GTPase activating protein 4,cytoplasm|Golgi apparatus|microtubule|growth cone|,negative regulation of fibroblast migration|negative regulation of axon extension|positive regulation of Rho GTPase activity|,Rho GTPase activator activity|,10,-0.1,0.36,10,0.1,0.0449,0,0,0,0.863,0,0,-1.4,1.5
ENSMUSG00000056752,DNAH9,"dynein, axonemal, heavy chain 9",axoneme|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0.8,1.6,0,0,0,0.863,0,0,-0.9,2
ENSMUSG00000018595,GLRA4,"glycine receptor, alpha 4 subunit",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|chloride channel complex|synapse|postsynaptic membrane|,transport|ion transport|chloride transport|,extracellular ligand-gated ion channel activity|chloride channel activity|glycine binding|transmitter-gated ion channel activity|,10,0,0,10,-0.3,0.269,0,0,0,0.863,0,0,-1.7,1.3
ENSMUSG00000037536,FBXO34,F-box protein 34,cellular_component|,biological_process|,molecular_function|,10,0.4,0.718,10,0,0,0,0,0,0.863,0,0,-1.1,1.8
ENSMUSG00000038412,HIGD1A,"HIG1 domain family, member 1A",mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|protein complex|respiratory chain|,transport|response to stress|cellular response to glucose starvation|negative regulation of apoptotic process|oxidation-reduction process|cellular response to hypoxia|negative regulation of release of cytochrome c from mitochondria|,molecular_function|,10,0.1,0.0472,10,-0.1,0.171,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000030722,NFATC2IP,"nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein",nucleus|cytoplasm|,cytokine production|positive regulation of transcription from RNA polymerase II promoter|,protein binding|,10,-0.1,0.0281,10,0.1,0.0546,0,0,0,0.863,0,0,-1.6,1.3
ENSMUSG00000038195,RILP,Rab interacting lysosomal protein,mitochondrion|lysosome|endosome|late endosome|membrane|cytoplasmic vesicle|protein complex|,transport|endosome to lysosome transport|protein transport|,protein binding|Rab GTPase binding|,10,-0.1,0.133,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000024875,YIF1A,Yip1 interacting factor homolog A (S. cerevisiae),endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|microtubule organizing center|membrane|integral component of membrane|intracellular membrane-bounded organelle|,transport|biological_process|protein transport|vesicle-mediated transport|,molecular_function|,10,0.1,0.061,10,0,0,0,0,0,0.863,0,0,-1.8,1.2
ENSMUSG00000033769,EXOC6B,exocyst complex component 6B,exocyst|cellular_component|,vesicle docking involved in exocytosis|biological_process|,molecular_function|,10,-0.1,0.184,10,0.8,0.0419,0,0,0,0.863,0,0,-1.4,1.8
ENSMUSG00000051444,BBS12,Bardet-Biedl syndrome 12 (human),intracellular|cell|cilium|cell projection|,intraciliary transport|eating behavior|cellular protein metabolic process|photoreceptor cell maintenance|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|chaperone-mediated protein complex assembly|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000022468,ENDOU,"endonuclease, polyU-specific",extracellular region|cytoplasm|,"proteolysis|immune response|RNA phosphodiester bond hydrolysis, endonucleolytic|","RNA binding|nuclease activity|endonuclease activity|endoribonuclease activity|scavenger receptor activity|hydrolase activity|hydrolase activity, acting on ester bonds|polysaccharide binding|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|",10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000020611,GNA13,"guanine nucleotide binding protein, alpha 13",intracellular|nucleus|cytoplasm|heterotrimeric G-protein complex|heterotrimeric G-protein complex|heterotrimeric G-protein complex|membrane|membrane|brush border membrane|brush border membrane|extracellular vesicular exosome|,angiogenesis|patterning of blood vessels|in utero embryonic development|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|small GTPase mediated signal transduction|Rho protein signal transduction|regulation of cell shape|cell differentiation|platelet activation|regulation of cell migration|activation of phospholipase D activity|activation of phospholipase D activity|intracellular signal transduction|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|GTPase activity|signal transducer activity|protein binding|GTP binding|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|type 1 angiotensin receptor binding|type 1 angiotensin receptor binding|D5 dopamine receptor binding|D5 dopamine receptor binding|metal ion binding|,9,0,0,9,0,0,0,0,0,0.863,0,0,-1.8,1.3
ENSMUSG00000022637,CBLB,Casitas B-lineage lymphoma b,intracellular|nucleus|cytoplasm|membrane raft|,positive regulation of T cell anergy|immune response|signal transduction|cell surface receptor signaling pathway|regulation of signaling|intracellular signal transduction|T cell activation|positive regulation of protein catabolic process|negative regulation of alpha-beta T cell proliferation|negative regulation of T cell receptor signaling pathway|,"phosphotyrosine binding|ubiquitin-protein transferase activity|signal transducer activity|calcium ion binding|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|protein kinase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",9,0,0,9,-0.1,0.113,0,0,0,0.863,0,0,-1.8,1.3
ENSMUSG00000024907,GAL,galanin,extracellular region|extracellular space|cytoplasm|Golgi apparatus|secretory granule|neuronal cell body|,inflammatory response|neuropeptide signaling pathway|nervous system development|feeding behavior|negative regulation of cell proliferation|protein kinase A signaling|cAMP-mediated signaling|regulation of glucocorticoid metabolic process|positive regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|negative regulation of lymphocyte proliferation|positive regulation of cortisol secretion|positive regulation of catagen|positive regulation of large conductance calcium-activated potassium channel activity|negative regulation of root hair elongation|,hormone activity|neuropeptide hormone activity|type 1 galanin receptor binding|type 2 galanin receptor binding|type 3 galanin receptor binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000026585,KIFAP3,kinesin-associated protein 3,condensed nuclear chromosome|endoplasmic reticulum|Golgi apparatus|centrosome|kinesin complex|spindle microtubule|axoneme|microtubule cytoskeleton|microtubule cytoskeleton|kinesin II complex|kinesin II complex|kinesin II complex|intraciliary transport particle|photoreceptor connecting cilium|ciliary basal body|extracellular vesicular exosome|periciliary membrane compartment|,microtubule-based process|protein localization|negative regulation of cell proliferation|negative regulation of apoptotic process|positive regulation of calcium-dependent cell-cell adhesion|,protein binding|kinesin binding|,10,0.1,0.0073,10,-0.2,0.382,0,0,0,0.863,0,0,-1.5,1.4
ENSMUSG00000063851,RNF183,ring finger protein 183,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.4,1.19,10,0.1,0.122,0,0,0,0.863,0,0,-1.7,1.2
ENSMUSG00000004929,THOP1,thimet oligopeptidase 1,intracellular|cytoplasm|,proteolysis|peptide metabolic process|intracellular signal transduction|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|hydrolase activity|peptide binding|metal ion binding|,10,-0.1,0.151,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000039347,ATP6V0E2,"ATPase, H+ transporting, lysosomal V0 subunit E2","membrane|integral component of membrane|proton-transporting V-type ATPase, V0 domain|",transport|ion transport|ATP hydrolysis coupled proton transport|proton transport|cell growth|,hydrogen ion transmembrane transporter activity|hydrolase activity|,10,-0.1,0.0329,10,0,0,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000026542,APCS,serum amyloid P-component,extracellular region|extracellular space|nucleus|extracellular matrix|protein complex|extracellular vesicular exosome|blood microparticle|,protein complex assembly|innate immune response|negative regulation of monocyte differentiation|negative regulation of viral entry into host cell|negative regulation of viral process|negative regulation of exo-alpha-sialidase activity|negative regulation of glycoprotein metabolic process|,complement component C1q binding|calcium ion binding|virion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000033233,TRIM45,tripartite motif-containing 45,intracellular|nucleus|cytoplasm|,bone development|,zinc ion binding|metal ion binding|,10,0,0,10,-0.2,0.139,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000025289,PRDX4,peroxiredoxin 4,extracellular region|extracellular space|nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|smooth endoplasmic reticulum|cytosol|extracellular vesicular exosome|,spermatogenesis|male gonad development|4-hydroxyproline metabolic process|protein maturation by protein folding|extracellular matrix organization|cell redox homeostasis|oxidation-reduction process|reactive oxygen species metabolic process|negative regulation of male germ cell proliferation|,peroxidase activity|antioxidant activity|oxidoreductase activity|protein homodimerization activity|peroxiredoxin activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000073719,VPS13D,vacuolar protein sorting 13 D (yeast),extracellular vesicular exosome|,biological_process|,molecular_function|,9,0,0,9,0,0,0,0,0,0.863,0,0,-1.5,1.7
ENSMUSG00000043621,UBXN10,UBX domain protein 10,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.177,10,0.1,0.0401,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000018581,DNAH11,"dynein, axonemal, heavy chain 11",None,cilium movement|determination of left/right symmetry|,nucleotide binding|ATP binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000079557,2-Mar,membrane-associated ring finger (C3HC4) 2,lysosome|endosome|endoplasmic reticulum|membrane|integral component of membrane|cytoplasmic vesicle|,endocytosis|protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.398,10,0.6,0.395,0,0,0,0.863,0,0,-0.9,1.9
ENSMUSG00000059201,LEP,leptin,extracellular region|extracellular space|extracellular space|intracellular|cell|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|ovulation from ovarian follicle|placenta development|regulation of protein phosphorylation|response to dietary excess|response to dietary excess|response to dietary excess|cardiac muscle hypertrophy|glucose metabolic process|regulation of gluconeogenesis|energy reserve metabolic process|glycerol biosynthetic process|lipid metabolic process|fatty acid beta-oxidation|signal transduction|tyrosine phosphorylation of STAT protein|cholesterol metabolic process|bile acid metabolic process|regulation of blood pressure|positive regulation of cell proliferation|adult feeding behavior|fatty acid catabolic process|negative regulation of metabolic process|regulation of metabolic process|central nervous system neuron development|insulin secretion|regulation of intestinal cholesterol absorption|negative regulation of appetite|response to insulin|leptin-mediated signaling pathway|positive regulation of peroxisome proliferator activated receptor signaling pathway|intracellular signal transduction|bone mineralization involved in bone maturation|positive regulation of protein import into nucleus|hormone metabolic process|positive regulation of tyrosine phosphorylation of Stat3 protein|glucose homeostasis|eating behavior|negative regulation of apoptotic process|positive regulation of ion transport|positive regulation of MAPK cascade|regulation of fat cell differentiation|positive regulation of myeloid cell differentiation|negative regulation of vasoconstriction|positive regulation of JAK-STAT cascade|positive regulation of JAK-STAT cascade|positive regulation of insulin receptor signaling pathway|positive regulation of developmental growth|regulation of insulin secretion|regulation of steroid biosynthetic process|leukocyte tethering or rolling|regulation of lipoprotein lipid oxidation|adipose tissue development|negative regulation of cartilage development|negative regulation of glucagon secretion|regulation of protein localization to nucleus|positive regulation of STAT protein import into nucleus|positive regulation of reactive oxygen species metabolic process|negative regulation of glutamine transport|positive regulation of hepatic stellate cell activation|,hormone activity|protein binding|growth factor activity|peptide hormone receptor binding|,9,0,0,9,-0.8,0.127,0,0,0,0.863,0,0,-2,0.8
ENSMUSG00000008763,MAN1A2,"mannosidase, alpha, class 1A, member 2",Golgi membrane|nucleolus|Golgi apparatus|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,respiratory gaseous exchange|metabolic process|glycoprotein metabolic process|lung alveolus development|,"mannosyl-oligosaccharide 1,2-alpha-mannosidase activity|calcium ion binding|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0,0,9,0,0,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000028780,SEMA3C,"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C",extracellular region|extracellular space|membrane|,neural crest cell migration|blood vessel remodeling|multicellular organismal development|nervous system development|axon guidance|heart development|post-embryonic development|cell differentiation|dichotomous subdivision of terminal units involved in salivary gland branching|,receptor activity|semaphorin receptor binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000020787,P2RX1,"purinergic receptor P2X, ligand-gated ion channel, 1",cell|integral component of nuclear inner membrane|plasma membrane|membrane|integral component of membrane|external side of cell outer membrane|neuron projection|protein complex|membrane raft|postsynaptic membrane|,"serotonin secretion by platelet|regulation of vascular smooth muscle contraction|transport|ion transport|ion transport|cation transport|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of smooth muscle contraction|insemination|regulation of blood pressure|response to organic substance|neuronal action potential|regulation of vasoconstriction|platelet activation|response to ATP|ion transmembrane transport|synaptic transmission, glutamatergic|purinergic nucleotide receptor signaling pathway|purinergic nucleotide receptor signaling pathway|vasoconstriction|positive regulation of ion transport|positive regulation of ion transport|ceramide biosynthetic process|protein homooligomerization|protein heterooligomerization|regulation of calcium ion transport|",purinergic nucleotide receptor activity|purinergic nucleotide receptor activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|ion channel activity|cation channel activity|cation channel activity|ATP binding|drug binding|zinc ion binding|,10,-0.3,0.111,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000048904,NEUROG1,neurogenin 1,nucleus|neuronal cell body|perikaryon|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|neurogenesis|cell differentiation|neuron differentiation|neuron differentiation|positive regulation of exit from mitosis|inner ear morphogenesis|cell fate commitment|regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of sequence-specific DNA binding transcription factor activity|",transcription factor binding transcription factor activity|DNA binding|chromatin binding|protein binding|protein dimerization activity|E-box binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.8,1.3
ENSMUSG00000068009,BPIFB6,"BPI fold containing family B, member 6",cellular_component|extracellular region|,biological_process|,lipid binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000019927,UBE2D1,ubiquitin-conjugating enzyme E2D 1,ubiquitin ligase complex|cytoplasm|protein complex|,protein polyubiquitination|protein polyubiquitination|ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination|protein K48-linked ubiquitination|,nucleotide binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|ATP binding|ligase activity|acid-amino acid ligase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000022357,KLHL38,kelch-like 38,cellular_component|,biological_process|,molecular_function|,10,0.2,0.271,10,0,0,0,0,0,0.863,0,0,-1.4,1.5
ENSMUSG00000024378,STARD4,StAR-related lipid transfer (START) domain containing 4,mitochondrion|,transport|lipid transport|,lipid binding|cholesterol binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000025359,PMEL,premelanosome protein,extracellular region|endosome|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|multivesicular body membrane|melanosome|melanosome|,melanosome organization|melanin biosynthetic process|,None,10,0,0,10,0.7,1.47,0,0,0,0.863,0,0,-0.8,2
ENSMUSG00000034623,PRSS55,"protease, serine 55",cellular_component|membrane|integral component of membrane|,proteolysis|biological_process|,molecular_function|catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.8
ENSMUSG00000021003,GALC,galactosylceramidase,mitochondrion|lysosome|extracellular vesicular exosome|,carbohydrate metabolic process|lipid metabolic process|sphingolipid metabolic process|galactosylceramide catabolic process|metabolic process|lipid catabolic process|,"galactosylceramidase activity|galactosylceramidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,-0.3,0.799,10,0,0,0,0,0,0.863,0,0,-1.7,1.2
ENSMUSG00000025759,MFSD8,major facilitator superfamily domain containing 8,nucleus|lysosome|lysosomal membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,transport|biological_process|transmembrane transport|,molecular_function|,10,0.1,0.213,10,0,0,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000028278,RRAGD,Ras-related GTP binding D,nucleus|cytoplasm|lysosome|,biological_process|,nucleotide binding|GTP binding|protein heterodimerization activity|,10,0,0,10,0.5,0.536,0,0,0,0.863,0,0,-0.9,2
ENSMUSG00000042744,GM15800,predicted gene 15800,cellular_component|,biological_process|,molecular_function|ligase activity|,10,0,0,10,-0.6,1.72,0,0,0,0.863,0,0,-2,0.8
ENSMUSG00000057286,ST6GALNAC2,"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|,"sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,9,0,0,0,0,0,0.863,0,0,-1.9,1.2
ENSMUSG00000017677,WSB1,WD repeat and SOCS box-containing 1,intracellular|,biological_process|intracellular signal transduction|,molecular_function|,10,0.5,0.606,10,-0.1,0.121,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000047257,PRSS45,"protease, serine 45",cellular_component|extracellular region|,proteolysis|,catalytic activity|serine-type endopeptidase activity|,10,0.1,0.0165,10,-0.1,0.278,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000022821,HGD,"homogentisate 1, 2-dioxygenase",extracellular vesicular exosome|,cellular amino acid metabolic process|L-phenylalanine catabolic process|tyrosine metabolic process|tyrosine catabolic process|oxidation-reduction process|,"homogentisate 1,2-dioxygenase activity|oxidoreductase activity|metal ion binding|dioxygenase activity|",10,-0.1,0.0134,10,0.1,0.135,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000067813,XKR9,X Kell blood group precursor related family member 9 homolog,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.176,0,0,0,0.863,0,0,-1.9,1.1
ENSMUSG00000040462,OS9,amplified in osteosarcoma,endoplasmic reticulum|endoplasmic reticulum lumen|,protein targeting|protein retention in ER lumen|protein ubiquitination|ER-associated ubiquitin-dependent protein catabolic process|response to endoplasmic reticulum stress|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,glycoprotein binding|protease binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000041538,H2-OB,"histocompatibility 2, O region beta locus",intracellular|lysosome|membrane|integral component of membrane|MHC class II protein complex|,immune system process|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of antigen processing and presentation of peptide antigen via MHC class II|,MHC class II protein complex binding|,10,-0.1,0.132,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000033196,MYH2,"myosin, heavy polypeptide 2, skeletal muscle, adult",Golgi apparatus|actomyosin contractile ring|muscle myosin complex|cell-cell junction|myosin complex|myofibril|myofibril|A band|protein complex|,plasma membrane repair|muscle contraction|response to activity|actin-mediated cell contraction|,nucleotide binding|actin binding|ATP binding|,10,0.1,0.0142,10,-0.9,1,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000041528,RNF123,ring finger protein 123,cytoplasm|,biological_process|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.2,0.294,0,0,0,0.863,0,0,-1.7,1.3
ENSMUSG00000059361,NRSN2,neurensin 2,plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|transport vesicle|neuronal cell body|,biological_process|,molecular_function|,10,-0.1,0.111,10,0,0,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000027804,PPID,peptidylprolyl isomerase D (cyclophilin D),nucleus|nucleolus|cytoplasm|mitochondrion|,negative regulation of transcription from RNA polymerase II promoter|protein peptidyl-prolyl isomerization|protein peptidyl-prolyl isomerization|protein folding|protein complex assembly|transport|apoptotic process|protein transport|lipid particle organization|positive regulation of apoptotic process|positive regulation of viral genome replication|positive regulation of protein secretion|chaperone-mediated protein folding|cellular response to UV-A|,peptidyl-prolyl cis-trans isomerase activity|peptidyl-prolyl cis-trans isomerase activity|FK506 binding|transcription factor binding|cyclosporin A binding|isomerase activity|enzyme binding|heat shock protein binding|peptide binding|Hsp90 protein binding|,10,0,0,10,0.2,0.237,0,0,0,0.863,0,0,-2,1
ENSMUSG00000087141,PLCXD2,"phosphatidylinositol-specific phospholipase C, X domain containing 2",cellular_component|,biological_process|,molecular_function|,10,0,0,10,1,0.296,0,0,0,0.863,0,0,-1.1,2
ENSMUSG00000030562,NOX4,NADPH oxidase 4,stress fiber|mitochondrion|endoplasmic reticulum|plasma membrane|focal adhesion|membrane|integral component of membrane|apical plasma membrane|cell junction|NADPH oxidase complex|perinuclear region of cytoplasm|cell periphery|,cell morphogenesis|superoxide metabolic process|cell aging|negative regulation of cell proliferation|positive regulation of smooth muscle cell migration|superoxide anion generation|positive regulation of apoptotic process|positive regulation of MAP kinase activity|bone resorption|homocysteine metabolic process|positive regulation of stress fiber assembly|positive regulation of protein kinase B signaling|cardiac muscle cell differentiation|oxidation-reduction process|oxidation-reduction process|positive regulation of ERK1 and ERK2 cascade|reactive oxygen species metabolic process|reactive oxygen species metabolic process|positive regulation of reactive oxygen species metabolic process|positive regulation of DNA biosynthetic process|,"NAD(P)H oxidase activity|superoxide-generating NADPH oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor|modified amino acid binding|",10,0,0,10,0.1,0.202,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000073700,KLHL21,kelch-like 21,cytoplasm|polar microtubule|cytoskeleton|Cul3-RING ubiquitin ligase complex|,cell cycle|mitotic nuclear division|protein ubiquitination|regulation of cytokinesis|chromosome passenger complex localization to spindle midzone|cell division|,ubiquitin-protein transferase activity|,10,-0.1,0.048,10,0,0,0,0,0,0.863,0,0,-1.4,1.5
ENSMUSG00000028455,STOML2,stomatin (Epb7.2)-like 2,immunological synapse|intracellular|cell|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial inner membrane|mitochondrial intermembrane space|plasma membrane|COP9 signalosome|actin cytoskeleton|membrane|extrinsic component of plasma membrane|extrinsic component of plasma membrane|T cell receptor complex|membrane raft|,"mitochondrial calcium ion transport|cellular calcium ion homeostasis|mitochondrion organization|lipid localization|positive regulation of mitochondrial membrane potential|interleukin-2 production|mitochondrial protein processing|CD4-positive, alpha-beta T cell activation|mitochondrial ATP synthesis coupled proton transport|mitochondrial ATP synthesis coupled proton transport|T cell receptor signaling pathway|protein oligomerization|positive regulation of mitochondrial DNA replication|positive regulation of cardiolipin metabolic process|stress-induced mitochondrial fusion|",lipid binding|cardiolipin binding|,10,0,0,10,-0.1,0.183,0,0,0,0.863,0,0,-1.4,1.7
ENSMUSG00000006546,CRYBA2,"crystallin, beta A2",None,lens development in camera-type eye|,structural constituent of eye lens|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.6
ENSMUSG00000051674,DCUN1D4,"DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)",nucleus|,biological_process|,molecular_function|,10,0,0,10,-0.7,1.5,0,0,0,0.863,0,0,-2,0.7
ENSMUSG00000033313,FBXL8,F-box and leucine-rich repeat protein 8,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.4,0.507,0,0,0,0.863,0,0,-1,1.9
ENSMUSG00000005371,FBXO11,F-box protein 11,nucleus|chromosome|nucleolus|cytoplasm|,cellular protein modification process|sensory perception of sound|peptidyl-arginine N-methylation|,ubiquitin-protein transferase activity|zinc ion binding|protein-arginine N-methyltransferase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000020805,SLC13A5,"solute carrier family 13 (sodium-dependent citrate transporter), member 5",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,transport|ion transport|sodium ion transport|tricarboxylic acid transport|succinate transport|succinate transport|citrate transport|citrate transport|tricarboxylic acid transmembrane transport|sodium ion transmembrane transport|transmembrane transport|succinate transmembrane transport|,transporter activity|organic acid:sodium symporter activity|citrate transmembrane transporter activity|citrate transmembrane transporter activity|succinate transmembrane transporter activity|succinate transmembrane transporter activity|tricarboxylic acid transmembrane transporter activity|symporter activity|sodium:dicarboxylate symporter activity|,10,0,0,10,0.1,0.124,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000051351,ZFP46,zinc finger protein 46,intracellular|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0.5,0.517,0,0,0,0.863,0,0,-1.1,1.9
ENSMUSG00000070336,FBXO47,F-box protein 47,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.3,1.8
ENSMUSG00000020109,DNAJB12,"DnaJ (Hsp40) homolog, subfamily B, member 12",membrane|membrane|integral component of membrane|,None,None,10,0,0,10,-0.2,0.416,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000069307,HIST1H2BQ,"histone cluster 1, H2bq",nucleus|extracellular vesicular exosome|,biological_process|,molecular_function|,1,0,0,1,0,0,0,0,0,0.863,0,0,-1.9,1.9
ENSMUSG00000054537,TMPRSS11E,"transmembrane protease, serine 11e",extracellular region|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,proteolysis|cognition|,catalytic activity|serine-type endopeptidase activity|protein binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,-0.1,0.212,0,0,0,0.863,0,0,-1.7,1.4
ENSMUSG00000024325,RING1,ring finger protein 1,ubiquitin ligase complex|sex chromatin|nucleus|cytoplasm|nuclear body|PcG protein complex|PcG protein complex|PRC1 complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|anterior/posterior pattern specification|anterior/posterior pattern specification|chromatin modification|histone ubiquitination|histone ubiquitination|histone H2A monoubiquitination|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|camera-type eye morphogenesis|","chromatin binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.315,10,0,0,0,0,0,0.863,0,0,-1.3,1.7
ENSMUSG00000025464,PAOX,polyamine oxidase (exo-N4-amino),cytoplasm|peroxisome|peroxisomal matrix|,polyamine catabolic process|polyamine catabolic process|putrescine biosynthetic process|putrescine catabolic process|spermidine catabolic process|spermine catabolic process|oxidation-reduction process|oxidation-reduction process|positive regulation of spermidine biosynthetic process|,"receptor binding|oxidoreductase activity|polyamine oxidase activity|polyamine oxidase activity|N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity|spermine:oxygen oxidoreductase (spermidine-forming) activity|spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity|N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity|N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity|",10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000015766,EPS8,epidermal growth factor receptor pathway substrate 8,cytoplasm|plasma membrane|cell cortex|postsynaptic density|membrane|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|stereocilium|ruffle membrane|cell projection|neuron projection|synapse|extracellular vesicular exosome|,adult locomotory behavior|regulation of cell shape|exit from mitosis|Rac protein signal transduction|regulation of actin filament length|actin cytoskeleton reorganization|dendritic cell migration|behavioral response to ethanol|barbed-end actin filament capping|barbed-end actin filament capping|actin filament bundle assembly|actin filament bundle assembly|actin filament bundle assembly|actin crosslink formation|actin crosslink formation|actin polymerization-dependent cell motility|,actin binding|protein binding|Rac GTPase binding|,9,0,0,9,0.6,0.704,0,0,0,0.863,0,0,-1.3,1.9
ENSMUSG00000027993,TRIM2,tripartite motif-containing 2,intracellular|cytoplasm|cytoplasm|,protein ubiquitination|regulation of neuron apoptotic process|regulation of neuron apoptotic process|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|myosin binding|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.1,0.254,10,0.1,0.0337,0,0,0,0.863,0,0,-1.4,1.6
ENSMUSG00000058145,ADAMTS17,"a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17",cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.1,0.0808,10,0,0,0,0,0,0.863,0,0,-1.6,1.4
ENSMUSG00000025935,TRAM1,translocating chain-associating membrane protein 1,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,transport|protein transport|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.2,1.8
ENSMUSG00000019433,GIPC1,"GIPC PDZ domain containing family, member 1",intracellular|cell|cytoplasm|cytosol|cytosol|brush border|cell cortex|synaptic vesicle|vesicle membrane|membrane|membrane|cytoplasmic membrane-bounded vesicle|endocytic vesicle|dendritic spine|dendritic shaft|extracellular vesicular exosome|,protein targeting|protein targeting|G-protein coupled receptor signaling pathway|synaptic transmission|glutamate secretion|positive regulation of transforming growth factor beta receptor signaling pathway|regulation of protein stability|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of cytokinesis|endothelial cell migration|positive regulation of GTPase activity|regulation of synaptic plasticity|,actin binding|GTPase activator activity|receptor binding|protein binding|myosin binding|PDZ domain binding|protein homodimerization activity|,10,-0.1,0.118,10,0,0,0,0,0,0.863,0,0,-1.5,1.5
ENSMUSG00000048175,ASB8,ankyrin repeat and SOCS box-containing 8,cytoplasm|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.6,1.5
ENSMUSG00000074480,MEX3A,mex3 homolog A (C. elegans),cellular_component|,biological_process|,poly(A) RNA binding|metal ion binding|,10,0.1,0.166,10,0,0,0,0,0,0.863,0,0,-1,2
ENSMUSG00000031074,FGF3,fibroblast growth factor 3,extracellular region|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|,organ induction|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|cell differentiation|otic vesicle formation|post-anal tail morphogenesis|thymus development|semicircular canal morphogenesis|positive regulation of cell division|negative regulation of cardiac muscle tissue development|,receptor binding|fibroblast growth factor receptor binding|protein binding|growth factor activity|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.4,1.7
ENSMUSG00000031758,CDYL2,"chromodomain protein, Y chromosome-like 2",nucleus|,biological_process|metabolic process|,catalytic activity|methylated histone binding|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.9,1.1
ENSMUSG00000071392,ECT2L,epithelial cell transforming sequence 2 oncogene-like,cellular_component|,biological_process|,molecular_function|,10,-0.6,2.12,10,0,0,0,0,0,0.863,0,0,-2,0.8
ENSMUSG00000004567,MCOLN1,mucolipin 1,cytoplasm|lysosome|lysosomal membrane|endosome|late endosome|plasma membrane|membrane|integral component of membrane|receptor complex|,transport|ion transport|cation transport|calcium ion transport|endosomal transport|ion transmembrane transport|release of sequestered calcium ion into cytosol|calcium ion transmembrane transport|,cation channel activity|NAADP-sensitive calcium-release channel activity|,10,0,0,10,-0.3,0.295,0,0,0,0.863,0,0,-1.8,1.1
ENSMUSG00000036067,SLC2A6,"solute carrier family 2 (facilitated glucose transporter), member 6",cellular_component|membrane|integral component of membrane|,transport|biological_process|carbohydrate transport|,molecular_function|,10,0,0,10,0.1,0.0477,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000034528,HSD17B13,hydroxysteroid (17-beta) dehydrogenase 13,cellular_component|extracellular region|,biological_process|metabolic process|oxidation-reduction process|,"molecular_function|oxidoreductase activity|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|versicolorin reductase activity|ketoreductase activity|",10,0,0,10,-0.1,0.0311,0,0,0,0.863,0,0,-1.8,1.2
ENSMUSG00000075376,RC3H2,ring finger and CCCH-type zinc finger domains 2,nucleus|cytoplasm|cell surface|membrane|,protein polyubiquitination|B cell homeostasis|post-embryonic development|regulation of gene expression|posttranscriptional regulation of gene expression|multicellular organism growth|T cell proliferation|T cell homeostasis|lung alveolus development|lymph node development|spleen development|limb development|T follicular helper cell differentiation|positive regulation of NIK/NF-kappaB signaling|,DNA binding|RNA binding|mRNA binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,-0.1,0.0762,0,0,0,0.863,0,0,-1.4,1.7
ENSMUSG00000029001,FBXO44,F-box protein 44,SCF ubiquitin ligase complex|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.863,0,0,-1.5,1.6
ENSMUSG00000019647,SEMA6A,"sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|,neuron migration|apoptotic process|cell surface receptor signaling pathway|multicellular organismal development|nervous system development|axon guidance|axon guidance|cell differentiation|centrosome localization|semaphorin-plexin signaling pathway|positive regulation of neuron migration|,receptor activity|transmembrane signaling receptor activity|protein binding|semaphorin receptor binding|semaphorin receptor binding|,10,0.1,0.0391,10,0,0,0,0,0,0.863,0,0,-1.2,1.7
ENSMUSG00000045053,KCNG3,"potassium voltage-gated channel, subfamily G, member 3",cytoplasm|endoplasmic reticulum|plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0,0,10,1,0.107,0,0,0,0.863,0,0,-0.8,2
ENSMUSG00000031382,ASB11,ankyrin repeat and SOCS box-containing 11,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,-0.2,0.248,10,0,0,0,0,0,0.863,0,0,-1.7,1.3
ENSMUSG00000025437,USP33,ubiquitin specific peptidase 33,cytoplasm|Golgi apparatus|centrosome|cytoskeleton|cell body|,proteolysis|ubiquitin-dependent protein catabolic process|endocytosis|axon guidance|regulation of G-protein coupled receptor protein signaling pathway|cell migration|protein deubiquitination|centrosome duplication|protein K63-linked deubiquitination|protein K48-linked deubiquitination|,G-protein coupled receptor binding|cysteine-type endopeptidase activity|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|zinc ion binding|hydrolase activity|ubiquitinyl hydrolase activity|metal ion binding|,10,0,0,10,-0.7,1.27,0,0,0,0.863,0,0,-2,0.9
ENSMUSG00000022488,NCKAP1L,NCK associated protein 1 like,cytosol|membrane|SCAR complex|SCAR complex|extracellular vesicular exosome|,"B cell homeostasis|myeloid cell homeostasis|protein complex assembly|chemotaxis|maintenance of cell polarity|neutrophil chemotaxis|positive regulation of actin filament polymerization|positive regulation of actin filament polymerization|cortical actin cytoskeleton organization|positive regulation of B cell proliferation|negative regulation of interleukin-17 production|negative regulation of interleukin-6 production|positive regulation of Rac GTPase activity|positive regulation of cell adhesion mediated by integrin|negative regulation of myosin-light-chain-phosphatase activity|positive regulation of T cell proliferation|positive regulation of phosphorylation|response to drug|T cell homeostasis|negative regulation of apoptotic process|positive regulation of CD4-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of B cell differentiation|positive regulation of gamma-delta T cell differentiation|positive regulation of lymphocyte differentiation|positive regulation of erythrocyte differentiation|positive regulation of protein kinase activity|B cell receptor signaling pathway|positive regulation of phagocytosis, engulfment|actin polymerization-dependent cell motility|positive regulation of neutrophil chemotaxis|",protein kinase activator activity|Rac GTPase activator activity|protein complex binding|,10,3.7,287,10,2.3,152,3.1,434,434,1.00E-05,1,1,2.7,4
ENSMUSG00000024560,CXXC1,CXXC finger 1 (PHD domain),nucleus|nuclear matrix|nuclear speck|histone methyltransferase complex|Set1C/COMPASS complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|histone H3-K4 methylation|",DNA binding|zinc ion binding|histone methyltransferase activity (H3-K4 specific)|unmethylated CpG binding|metal ion binding|,10,0.8,25.7,10,2.1,42.3,0.9,65.3,65.3,1.00E-05,1,1,0.8,2
ENSMUSG00000090213,TMEM189,transmembrane protein 189,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.1,39.3,10,0.8,25,1,62.7,62.7,1.00E-05,1,1,0.7,1.4
ENSMUSG00000029388,EIF2B1,"eukaryotic translation initiation factor 2B, subunit 1 (alpha)",cytoplasm|cytoplasm|eukaryotic translation initiation factor 2 complex|eukaryotic translation initiation factor 2B complex|eukaryotic translation initiation factor 2B complex|plasma membrane|membrane|,translation|translational initiation|regulation of translation|regulation of translational initiation|response to heat|response to glucose|oligodendrocyte development|negative regulation of translational initiation in response to stress|response to peptide hormone|positive regulation of GTPase activity|positive regulation of GTPase activity|cellular metabolic process|regulation of catalytic activity|cellular response to stimulus|,translation initiation factor activity|translation initiation factor activity|guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|protein binding|GTP binding|GDP binding|enzyme regulator activity|,8,-1.7,36.9,7,-1.6,23.2,-1.7,59.5,-59.5,1.00E-05,1,1,-2.6,-1.2
ENSMUSG00000028266,LMO4,LIM domain only 4,transcription factor complex|,"neural tube closure|ventricular septum development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|ventral spinal cord interneuron differentiation|spinal cord motor neuron differentiation|spinal cord association neuron differentiation|negative regulation of protein complex assembly|regulation of cell fate specification|positive regulation of transcription from RNA polymerase II promoter|thymus development|regulation of cell activation|",enhancer sequence-specific DNA binding|protein binding|transcription factor binding|zinc ion binding|metal ion binding|,10,0.7,24.2,10,1.1,36.1,1,58,58,1.00E-05,1,1,0.7,1.3
ENSMUSG00000028587,ORC1,"origin recognition complex, subunit 1",origin recognition complex|nucleus|nucleus|nuclear origin of replication recognition complex|nucleolus|cytoplasm|plasma membrane|,DNA replication|,nucleotide binding|DNA binding|chromatin binding|ATP binding|,10,1.2,26.4,10,1.8,24.6,1.6,49.6,49.6,5.00E-05,1,1,0.9,2.6
ENSMUSG00000007817,ZMIZ1,"zinc finger, MIZ-type containing 1",nucleus|cytoplasm|,"vasculogenesis|in utero embryonic development|heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|vitellogenesis|cell aging|positive regulation of transcription from RNA polymerase II promoter|positive regulation of fibroblast proliferation|developmental growth|artery morphogenesis|",zinc ion binding|metal ion binding|,9,-0.7,15.6,9,-1,32.3,-1,47.4,-47.4,0.00014,1,1,-1.4,-0.7
ENSMUSG00000039810,ZC3H10,zinc finger CCCH type containing 10,None,None,poly(A) RNA binding|metal ion binding|,10,-1.4,33.3,10,-1.3,8.64,-1.4,41.4,-41.4,0.00038,1,1,-2.2,-0.9
ENSMUSG00000024456,DIAP1,diaphanous homolog 1 (Drosophila),cytoplasm|cytoskeleton|plasma membrane|membrane|ruffle membrane|cell projection|neuron projection|mitotic spindle|,cytoskeleton organization|actin filament organization|sensory perception of sound|regulation of cell shape|cellular component organization|actin cytoskeleton organization|actin filament polymerization|positive regulation of cell migration|neuron projection development|regulation of microtubule-based process|protein localization to microtubule|regulation of release of sequestered calcium ion into cytosol|cellular response to histamine|,actin binding|protein binding|profilin binding|Rho GTPase binding|identical protein binding|ion channel binding|ion channel binding|poly(A) RNA binding|,10,1.4,35.8,10,0.8,6.77,1.2,40.4,40.4,0.00043,1,1,0.7,1.9
ENSMUSG00000031627,IRF2,interferon regulatory factor 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",regulatory region DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.6,14.2,10,-1.1,30.3,-1,39.7,-39.7,0.00043,1,1,-1.4,-0.6
ENSMUSG00000025872,THOC3,THO complex 3,transcription export complex|THO complex part of transcription export complex|nucleus|,mRNA processing|mRNA export from nucleus|transport|RNA splicing|viral mRNA export from host cell nucleus|mRNA transport|,RNA binding|protein binding|,9,0.6,9.25,9,0.9,32,0.8,39.5,39.5,0.00043,1,1,0.6,1.2
ENSMUSG00000028910,MECR,mitochondrial trans-2-enoyl-CoA reductase,nucleus|mitochondrion|mitochondrion|cytosol|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|oxidation-reduction process|,receptor binding|zinc ion binding|oxidoreductase activity|ligand-dependent nuclear receptor binding|trans-2-enoyl-CoA reductase (NADPH) activity|,10,0.7,3.84,10,2,37.3,1.9,36.2,36.2,0.00052,1,1,1.2,3.6
ENSMUSG00000028683,EIF2B3,"eukaryotic translation initiation factor 2B, subunit 3",cytoplasm|eukaryotic translation initiation factor 2B complex|,translational initiation|regulation of translation|response to heat|response to glucose|oligodendrocyte development|negative regulation of translational initiation in response to stress|response to peptide hormone|positive regulation of GTPase activity|cellular response to stimulus|,"translation initiation factor activity|guanyl-nucleotide exchange factor activity|guanyl-nucleotide exchange factor activity|translation factor activity, nucleic acid binding|",10,-1.8,29.7,10,-1.3,8.29,-1.7,36,-36,0.00053,1,1,-2.6,-1
ENSMUSG00000027655,DHX35,DEAH (Asp-Glu-Ala-His) box polypeptide 35,catalytic step 2 spliceosome|,biological_process|,nucleotide binding|molecular_function|ATP binding|hydrolase activity|,10,1,14,10,1.4,21.7,1,34.6,34.6,0.00062,1,1,0.7,1.8
ENSMUSG00000034640,TIPARP,TCDD-inducible poly(ADP-ribose) polymerase,nucleus|,vasculogenesis|kidney development|protein ADP-ribosylation|nitrogen compound metabolic process|androgen metabolic process|estrogen metabolic process|female gonad development|post-embryonic development|negative regulation of gene expression|hemopoiesis|multicellular organismal metabolic process|positive regulation of protein catabolic process|platelet-derived growth factor receptor signaling pathway|skeletal system morphogenesis|smooth muscle tissue development|palate development|face morphogenesis|cellular response to organic cyclic compound|,"NAD+ ADP-ribosyltransferase activity|NAD+ ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|enhancer binding|metal ion binding|",9,-0.8,24.5,9,-0.5,12,-0.7,34.6,-34.6,0.00062,1,1,-1.1,-0.5
ENSMUSG00000034748,SIRT6,sirtuin 6,nucleus|nucleoplasm|nuclear telomeric heterochromatin|,protein ADP-ribosylation|regulation of double-strand break repair via homologous recombination|histone H3 deacetylation|,"chromatin binding|NAD(P)+-protein-arginine ADP-ribosyltransferase activity|histone deacetylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|metal ion binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|NAD+ binding|",10,-0.4,1.58,10,-1.6,31.7,-0.4,30.6,-30.6,0.00105,0,1,-2.4,-0.3
ENSMUSG00000037426,DEPDC5,DEP domain containing 5,cytoplasm|lysosomal membrane|cytosol|perinuclear region of cytoplasm|,biological_process|intracellular signal transduction|,molecular_function|GTPase activator activity|,10,-0.6,13.7,10,-1.2,19.8,-0.9,30.3,-30.3,0.00112,0,1,-1.4,-0.5
ENSMUSG00000052331,ANKRD44,ankyrin repeat domain 44,cellular_component|,biological_process|,molecular_function|,10,1,15.2,10,0.8,16.5,0.8,30.3,30.3,0.00112,0,1,0.6,1.3
ENSMUSG00000051149,ADNP,activity-dependent neuroprotective protein,extracellular space|extracellular space|nucleus|nucleus|cytoplasm|axon|dendrite|neuronal cell body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|short-term memory|negative regulation of gene expression|regulation of protein ADP-ribosylation|positive regulation of neuron projection development|positive regulation of cGMP biosynthetic process|negative regulation of protein binding|activation of protein kinase activity|nitric oxide homeostasis|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of axon extension|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of synaptic transmission|positive regulation of synapse assembly|",DNA binding|chromatin binding|copper ion binding|protein binding|peptide binding|metal ion binding|beta-tubulin binding|,10,0.7,12.9,10,0.9,17,0.8,29.1,29.1,0.00145,0,1,0.5,1.2
ENSMUSG00000035011,ZBTB7A,zinc finger and BTB domain containing 7a,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell differentiation|regulation of osteoclast differentiation|negative regulation of transcription, DNA-templated|cartilage development|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|histone acetyltransferase binding|metal ion binding|,10,0.9,18.4,10,0.6,12.1,0.8,29,29,0.0015,0,1,0.5,1.2
ENSMUSG00000018565,ELP5,elongator acetyltransferase complex subunit 5,nucleus|cytoplasm|Elongator holoenzyme complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell migration|",None,8,-0.5,2.67,9,1,30.9,1,28.7,28.7,0.00161,0,1,0.6,1.6
ENSMUSG00000049672,ZBTB14,zinc finger and BTB domain containing 14,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0.8,21.3,10,0.7,7.69,0.7,28.5,28.5,0.00168,0,1,0.5,1.1
ENSMUSG00000051220,ERCC6L,excision repair cross-complementing rodent repair deficiency complementation group 6 like,"chromosome, centromeric region|kinetochore|chromosome|membrane|",cell cycle|mitotic nuclear division|biological_process|cell division|,nucleotide binding|DNA binding|helicase activity|ATP binding|hydrolase activity|,10,1.1,5.36,10,1.8,25.3,1.6,28.3,28.3,0.00178,0,1,0.9,2.8
ENSMUSG00000042507,ELMSAN1,ELM2 and Myb/SANT-like domain containing 1,nucleus|,biological_process|,molecular_function|,10,0.7,13.2,10,0.6,14.7,0.7,27.2,27.2,0.00221,0,1,0.4,1
ENSMUSG00000004364,CUL3,cullin 3,Golgi membrane|nucleus|Golgi apparatus|polar microtubule|membrane|cullin-RING ubiquitin ligase complex|Cul3-RING ubiquitin ligase complex|extracellular vesicular exosome|,mitotic anaphase|protein polyubiquitination|cell morphogenesis|cytokinesis|in utero embryonic development|trophectodermal cellular morphogenesis|ubiquitin-dependent protein catabolic process|protein monoubiquitination|transport|ER to Golgi vesicle-mediated transport|integrin-mediated signaling pathway|gastrulation|cyclin catabolic process|Wnt signaling pathway|vesicle-mediated transport|cell migration|protein ubiquitination|stem cell division|positive regulation of cytokinesis|negative regulation of Rho protein signal transduction|embryonic cleavage|stress fiber assembly|proteasome-mediated ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|COPII vesicle coating|anaphase|,ubiquitin-protein transferase activity|protein binding|cyclin binding|POZ domain binding|ubiquitin protein ligase binding|protein homodimerization activity|protein heterodimerization activity|,9,-0.8,13.6,9,-1,13.6,-0.9,26.6,-26.6,0.00259,0,1,-1.5,-0.6
ENSMUSG00000093938,EVI2B,ecotropic viral integration site 2b,membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.9,9.1,9,0.8,17.7,0.9,26.2,26.2,0.00287,0,1,0.5,1.3
ENSMUSG00000072872,RYBP,RING1 and YY1 binding protein,nucleus|nucleoplasm|cytoplasm|PcG protein complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|histone H2A monoubiquitination|",DNA binding|transcription corepressor activity|protein binding|zinc ion binding|metal ion binding|,10,0.8,13.1,10,0.8,13.5,0.8,26.2,26.2,0.00287,0,1,0.6,1.3
ENSMUSG00000034259,EXOSC4,exosome component 4,exosome (RNase complex)|nucleus|cytoplasm|transcriptionally active chromatin|,maturation of 5.8S rRNA|nuclear-transcribed mRNA catabolic process|rRNA processing|positive regulation of cell growth|DNA deamination|defense response to virus|nuclear mRNA surveillance|histone mRNA catabolic process|,RNA binding|protein binding|AU-rich element binding|,8,-1.5,24.9,8,1,6.44,-1.4,26.2,-26.2,0.00287,0,1,-2.6,-0.4
ENSMUSG00000020472,ZKSCAN17,zinc finger with KRAB and SCAN domains 17,intracellular|nucleus|nuclear body|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein self-association|protein self-association|metal ion binding|,10,-1.6,28.9,10,0.2,0.948,-1.6,25.4,-25.4,0.00355,0,0,-2.9,-0.8
ENSMUSG00000036528,PPFIBP2,"PTPRF interacting protein, binding protein 2 (liprin beta 2)",extracellular space|,DNA integration|,DNA binding|integrase activity|,10,0.8,5.06,10,1.9,22.9,1.8,24.1,24.1,0.00518,0,0,0.7,3
ENSMUSG00000038299,WDR36,WD repeat domain 36,cellular_component|,retina homeostasis|regulation of axon extension|,poly(A) RNA binding|,7,1.7,24,8,-0.8,8.03,1.7,23.5,23.5,0.00595,0,0,0.9,3
ENSMUSG00000035297,COPS4,"COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)",nucleus|cytoplasm|synaptic vesicle|COP9 signalosome|COP9 signalosome|cell junction|cytoplasmic vesicle|synapse|extracellular vesicular exosome|,protein deneddylation|cullin deneddylation|,protein binding|,8,1.3,6.23,8,1.1,17.6,1.3,23,23,0.00693,0,0,0.9,1.9
ENSMUSG00000003662,CIAO1,cytosolic iron-sulfur protein assembly 1,MMXD complex|CIA complex|,regulation of transcription from RNA polymerase II promoter|chromosome segregation|iron-sulfur cluster assembly|,sequence-specific DNA binding transcription factor activity|,7,-2,25.6,7,0.8,3.97,-2,22.4,-22.4,0.00842,0,0,-4,-1.5
ENSMUSG00000028668,TCEB3,"transcription elongation factor B (SIII), polypeptide 3",extracellular space|nucleus|transcription elongation factor complex|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription elongation from RNA polymerase II promoter|",DNA binding|,10,0.6,12.8,10,0.7,9.91,0.7,22.3,22.3,0.00868,0,0,0.4,1
ENSMUSG00000018932,MAP2K3,mitogen-activated protein kinase kinase 3,intracellular|cytosol|membrane|,"MAPK cascade|MAPK cascade|activation of MAPK activity|activation of MAPK activity|protein phosphorylation|inflammatory response|phosphorylation|signal transduction by phosphorylation|intracellular signal transduction|regulation of cytokine biosynthetic process|positive regulation of protein kinase activity|positive regulation of transcription, DNA-templated|cardiac muscle contraction|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|MAP kinase kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein kinase binding|",9,0.5,11.2,9,0.5,11,0.5,21.8,21.8,0.01,0,0,0.3,1
ENSMUSG00000020358,HNRNPAB,heterogeneous nuclear ribonucleoprotein A/B,nucleus|cytoplasm|virion|viral nucleocapsid|ribonucleoprotein complex|,"negative regulation of transcription from RNA polymerase II promoter|epithelial to mesenchymal transition|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",nucleotide binding|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA binding|protein binding|sequence-specific DNA binding|poly(A) RNA binding|,10,0.8,18.6,10,0.4,4.99,0.7,21.4,21.4,0.0112,0,0,0.4,1.4
ENSMUSG00000006392,MED8,mediator complex subunit 8,nucleus|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|,10,2.1,23,10,0.6,1.71,2,21,21,0.0131,0,0,1.3,4
ENSMUSG00000014907,NAF1,nuclear assembly factor 1 homolog (S. cerevisiae),nucleus|small nucleolar ribonucleoprotein complex|cytoplasm|ribonucleoprotein complex|,pseudouridine synthesis|rRNA processing|ribosome biogenesis|,RNA binding|poly(A) RNA binding|,9,2,22.7,8,-1.1,8.14,2,20.8,20.8,0.014,0,0,1.4,4
ENSMUSG00000020400,TNIP1,TNFAIP3 interacting protein 1,nucleus|cytoplasm|,MyD88-dependent toll-like receptor signaling pathway|inflammatory response|leukocyte cell-cell adhesion|glycoprotein biosynthetic process|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of transcription from RNA polymerase II promoter|positive regulation of inflammatory response|negative regulation of ERK1 and ERK2 cascade|modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|,ubiquitin-specific protease activity|protein binding|polyubiquitin binding|mitogen-activated protein kinase binding|,10,-0.9,16.6,10,-0.4,6.99,-0.7,20.7,-20.7,0.0144,0,0,-1.2,-0.4
ENSMUSG00000024604,RBM22,RNA binding motif protein 22,nucleus|spliceosomal complex|cytoplasm|catalytic step 2 spliceosome|,"protein import into nucleus, translocation|mRNA processing|transport|RNA splicing|positive regulation of RNA splicing|cellular response to drug|mRNA cis splicing, via spliceosome|positive regulation of intracellular protein transport|",nucleotide binding|nucleic acid binding|RNA binding|nucleocytoplasmic transporter activity|snRNA binding|pre-mRNA binding|poly(A) RNA binding|metal ion binding|calcium-dependent protein binding|,9,0.7,7.52,8,1.2,15,1.1,20.5,20.5,0.0153,0,0,0.6,1.7
ENSMUSG00000023988,BYSL,bystin-like,nucleus|nucleolus|nucleolus|cytoplasm|cytoplasm|cytoplasmic microtubule|membrane|cell projection|intracellular membrane-bounded organelle|apical part of cell|perinuclear region of cytoplasm|,"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|in utero embryonic development|blastocyst formation|trophectodermal cell differentiation|cell adhesion|cell proliferation|ribosome biogenesis|",poly(A) RNA binding|,10,0.2,0.265,10,-1.7,23.6,-1.6,20.2,-20.2,0.0171,0,0,-3,-0.4
ENSMUSG00000044452,ZFP507,zinc finger protein 507,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,1.9,23.9,10,-0.2,1.9,1.9,20.2,20.2,0.0171,0,0,1.2,3
ENSMUSG00000066000,2610305D13RIK,RIKEN cDNA 2610305D13 gene,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.3,0.441,10,-1.7,22.8,-1.7,19.9,-19.9,0.0191,0,0,-3,-0.3
ENSMUSG00000039205,CIZ1,CDKN1A interacting zinc finger protein 1,cell|nucleus|nucleus|,positive regulation of DNA-dependent DNA replication initiation|positive regulation of DNA-dependent DNA replication initiation|maintenance of protein location in nucleus|,cyclin binding|metal ion binding|,10,-0.1,0.292,10,1.9,22.6,1.9,19.4,19.4,0.0229,0,0,1,3
ENSMUSG00000051579,TCEAL8,transcription elongation factor A (SII)-like 8,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,10,-1.6,22.7,10,0,0,-1.6,19.3,-19.3,0.0239,0,0,-3,-0.8
ENSMUSG00000037275,GEMIN5,gem (nuclear organelle) associated protein 5,nucleus|nucleoplasm|cytoplasm|cytosol|membrane|nuclear body|SMN complex|SMN-Sm protein complex|,spliceosomal snRNP assembly|mRNA processing|RNA splicing|,RNA binding|snRNA binding|poly(A) RNA binding|,9,-1.2,11.1,9,-1.1,8.59,-1.2,19.2,-19.2,0.0249,0,0,-1.9,-0.7
ENSMUSG00000024135,SRBD1,S1 RNA binding domain 1,cellular_component|,nucleobase-containing compound metabolic process|biological_process|,"molecular_function|nucleic acid binding|RNA binding|hydrolase activity, acting on ester bonds|",10,0.7,10.2,10,0.8,9.33,0.8,19,19,0.0266,0,0,0.5,1.3
ENSMUSG00000031060,RBM10,RNA binding motif protein 10,nucleus|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of cell proliferation|negative regulation of cell proliferation|regulation of smooth muscle cell apoptotic process|positive regulation of smooth muscle cell apoptotic process|3'-UTR-mediated mRNA stabilization|,nucleotide binding|nucleic acid binding|RNA binding|zinc ion binding|protein complex binding|identical protein binding|poly(A) RNA binding|metal ion binding|,10,0.3,2.55,10,1.7,19.2,1.6,18.4,18.4,0.0307,0,0,0.3,3
ENSMUSG00000020300,CPEB4,cytoplasmic polyadenylation element binding protein 4,nucleus|nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|postsynaptic density|dendrite|dendrite|synapse|,response to ischemia|ionotropic glutamate receptor signaling pathway|cellular response to decreased oxygen levels|cellular response to glucose starvation|negative regulation of neuron apoptotic process|cellular response to amino acid stimulus|cellular response to amino acid stimulus|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.6,13.4,10,0.4,6.72,0.4,18.4,18.4,0.0307,0,0,0.3,0.9
ENSMUSG00000030423,POP4,"processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)",ribonuclease MRP complex|nucleus|nucleolar ribonuclease P complex|ribonuclease P complex|,rRNA processing|mRNA cleavage|tRNA processing|,RNA binding|ribonuclease P activity|ribonuclease activity|hydrolase activity|,10,-0.4,3.41,10,-1.7,18.3,-1.6,17.9,-17.9,0.0335,0,0,-3,-0.3
ENSMUSG00000024914,DRAP1,Dr1 associated protein 1 (negative cofactor 2 alpha),intracellular|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|transcription corepressor activity|protein binding|transcription factor binding|sequence-specific DNA binding|protein heterodimerization activity|,9,1.4,12.7,9,0.7,5.77,0.7,17.4,17.4,0.0351,0,0,0.4,1.7
ENSMUSG00000017299,DNTTIP1,"deoxynucleotidyltransferase, terminal, interacting protein 1",nucleus|,positive regulation of catalytic activity|,DNA binding|enzyme activator activity|transferase activity|protein homodimerization activity|,10,0.4,2.84,10,0.5,14.8,0.5,17,17,0.0361,0,0,0.3,0.8
ENSMUSG00000002345,2310045N01RIK,RIKEN cDNA 2310045N01 gene,cellular_component|,biological_process|,molecular_function|,10,1.1,14.7,10,0.6,2.41,0.7,16.4,16.4,0.0374,0,0,0.5,1.7
ENSMUSG00000028633,CTPS,cytidine 5'-triphosphate synthase,membrane|,pyrimidine nucleotide biosynthetic process|CTP biosynthetic process|glutamine metabolic process|,nucleotide binding|CTP synthase activity|ATP binding|ligase activity|,10,0.3,2.17,10,0.9,15.2,0.9,16.3,16.3,0.0376,0,0,-0.6,2
ENSMUSG00000030677,KIF22,kinesin family member 22,chromatin|nucleus|cytoplasm|spindle|cytoskeleton|kinesin complex|microtubule|focal adhesion|,DNA repair|microtubule-based movement|,nucleotide binding|DNA binding|microtubule motor activity|ATP binding|microtubule binding|,10,-0.9,11.7,10,-1.2,5.68,-1,16.3,-16.3,0.0376,0,0,-1.7,-0.6
ENSMUSG00000032212,SLTM,"SAFB-like, transcription modulator",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|biological_process|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.6,5.9,10,0.7,11.4,0.6,16.2,16.2,0.0378,0,0,0.4,1.1
ENSMUSG00000023025,LARP4,"La ribonucleoprotein domain family, member 4",membrane|,cytoskeleton organization|regulation of cell morphogenesis|,nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.7,8.33,10,0.7,8.09,0.7,16,16,0.0383,0,0,0.4,1.1
ENSMUSG00000030942,THUMPD1,THUMP domain containing 1,cellular_component|,biological_process|,RNA binding|poly(A) RNA binding|,10,0.7,6.07,10,0.8,10.4,0.7,15.9,15.9,0.0384,0,0,0.3,1.2
ENSMUSG00000078495,GM13157,predicted gene 13157,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-1.4,16,10,-0.3,3.24,-0.3,15.7,-15.7,0.0389,0,0,-2.5,-0.2
ENSMUSG00000025451,PAIP1,polyadenylate binding protein-interacting protein 1,cellular_component|cytoplasm|,regulation of translation|positive regulation of translation|,RNA binding|protein binding|translation activator activity|,10,0.7,9.8,10,1.4,7.42,1.2,15,15,0.0401,0,0,0.5,1.8
ENSMUSG00000002455,PRPF6,PRP6 pre-mRNA splicing factor 6 homolog (yeast),intracellular|nucleus|spliceosomal complex|U5 snRNP|membrane|U4/U6 x U5 tri-snRNP complex|U4/U6 snRNP|catalytic step 2 spliceosome|,"spliceosomal tri-snRNP complex assembly|mRNA splicing, via spliceosome|RNA processing|mRNA processing|RNA localization|RNA splicing|positive regulation of transcription from RNA polymerase II promoter|",transcription coactivator activity|RNA binding|ribonucleoprotein complex binding|poly(A) RNA binding|androgen receptor binding|,8,-0.6,7.77,8,0.8,14.1,0.9,14.9,14.9,0.0402,0,0,0.4,1.8
ENSMUSG00000030557,MEF2A,myocyte enhancer factor 2A,nuclear chromatin|nucleus|nucleus|nucleus|cytoplasm|,"mitochondrial genome maintenance|negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|apoptotic process|multicellular organismal development|nervous system development|cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|mitochondrion distribution|dendrite morphogenesis|ventricular cardiac myofibril assembly|cardiac conduction|ERK5 cascade|cellular response to calcium ion|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II transcription coactivator activity|DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|protein kinase binding|activating transcription factor binding|activating transcription factor binding|histone acetyltransferase binding|histone deacetylase binding|sequence-specific DNA binding|sequence-specific DNA binding|SMAD binding|protein heterodimerization activity|protein dimerization activity|,10,-0.8,5.84,10,-0.8,9.1,-0.8,14.6,-14.6,0.0406,0,0,-1.4,-0.4
ENSMUSG00000063358,MAPK1,mitogen-activated protein kinase 1,nucleus|nucleus|nucleus|nucleoplasm|cytoplasm|cytoplasm|mitochondrion|mitochondrion|early endosome|late endosome|Golgi apparatus|cytosol|cytosol|cytosol|cytoskeleton|caveola|focal adhesion|microtubule cytoskeleton|axon|pseudopodium|dendrite cytoplasm|perikaryon|protein complex|extracellular vesicular exosome|,"MAPK cascade|MAPK cascade|MAPK cascade|MAPK import into nucleus|transcription, DNA-templated|protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|cellular response to DNA damage stimulus|cell cycle|signal transduction|response to toxic substance|organ morphogenesis|positive regulation of peptidyl-threonine phosphorylation|phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|sensory perception of pain|cytosine metabolic process|lipopolysaccharide-mediated signaling pathway|response to lipopolysaccharide|regulation of stress-activated MAPK cascade|mammary gland epithelial cell proliferation|intracellular signal transduction|ERBB signaling pathway|response to exogenous dsRNA|response to estrogen|negative regulation of cell differentiation|positive regulation of translation|T cell receptor signaling pathway|B cell receptor signaling pathway|regulation of sequence-specific DNA binding transcription factor activity|regulation of cytoskeleton organization|labyrinthine layer blood vessel development|ERK1 and ERK2 cascade|response to epidermal growth factor|cellular response to organic substance|caveolin-mediated endocytosis|regulation of Golgi inheritance|cellular response to granulocyte macrophage colony-stimulating factor stimulus|regulation of early endosome to late endosome transport|","nucleotide binding|phosphotyrosine binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|MAP kinase activity|MAP kinase activity|MAP kinase activity|protein binding|ATP binding|transcription factor binding|RNA polymerase II carboxy-terminal domain kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|phosphatase binding|mitogen-activated protein kinase kinase kinase binding|",10,1.2,2.25,10,-0.6,13.5,-0.5,14.4,-14.4,0.0409,0,0,-1.1,-0.3
ENSMUSG00000040481,BPTF,bromodomain PHD finger transcription factor,nucleus|cytoplasm|microtubule cytoskeleton|NURF complex|,"negative regulation of transcription from RNA polymerase II promoter|embryonic placenta development|ATP catabolic process|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|brain development|endoderm development|anterior/posterior pattern specification|positive regulation of transcription, DNA-templated|",DNA-dependent ATPase activity|transcription factor binding|sequence-specific DNA binding|metal ion binding|,10,0.5,7.4,10,0.4,6.81,0.5,13.8,13.8,0.0421,0,0,0.3,0.9
ENSMUSG00000027014,CWC22,CWC22 spliceosome-associated protein homolog (S. cerevisiae),nucleus|spliceosomal complex|cytoplasm|nuclear speck|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,RNA binding|,9,-0.9,14.7,9,1.1,8.29,-0.9,13.7,-13.7,0.0423,0,0,-1.7,-0.4
ENSMUSG00000022377,ASAP1,"ArfGAP with SH3 domain, ankyrin repeat and PH domain1",cytoplasm|membrane|,cell projection organization|regulation of ARF GTPase activity|positive regulation of GTPase activity|cilium morphogenesis|,"GTPase activator activity|protein binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|ARF GTPase activator activity|zinc ion binding|metal ion binding|",10,0.6,8.43,10,0.5,5.29,0.6,13.3,13.3,0.0433,0,0,0.3,1.3
ENSMUSG00000024622,HMGXB3,HMG box domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0.6,8.31,10,0.9,5.4,0.6,12.9,12.9,0.0443,0,0,0.2,1.2
ENSMUSG00000027236,EIF3J1,"eukaryotic translation initiation factor 3, subunit J1",eukaryotic translation initiation factor 3 complex|,biological_process|,molecular_function|,6,-1.1,12.1,6,-0.6,2.35,-1.1,12.8,-12.8,0.0446,0,0,-1.8,-0.5
ENSMUSG00000022160,METTL3,methyltransferase like 3,nucleus|nuclear speck|MIS complex|,RNA methylation|nucleobase-containing compound metabolic process|mRNA processing|circadian rhythm|mRNA modification|stem cell maintenance|methylation|rhythmic process|mRNA destabilization|mRNA methylation|mRNA methylation|mRNA methylation|,mRNA (N6-adenosine)-methyltransferase activity|RNA binding|protein binding|methyltransferase activity|mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity|mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity|mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity|transferase activity|,8,-1.3,14.3,8,0.1,0.37,-1.3,12.7,-12.7,0.0449,0,0,-2,-0.5
ENSMUSG00000025223,LDB1,LIM domain binding 1,nuclear chromatin|nucleus|nucleus|transcription factor complex|protein complex|protein complex|,"transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery|gastrulation with mouth forming second|hair follicle development|transcription from RNA polymerase II promoter|multicellular organismal development|anterior/posterior axis specification|epithelial structure maintenance|Wnt signaling pathway|cerebellum development|cerebellar Purkinje cell differentiation|cellular component assembly|regulation of DNA-templated transcription, elongation|somatic stem cell maintenance|histone H3-K4 acetylation|negative regulation of erythrocyte differentiation|positive regulation of cell adhesion|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hemoglobin biosynthetic process|primitive erythrocyte differentiation|head development|regulation of RNA biosynthetic process|",transcription factor binding transcription factor activity|RNA polymerase II activating transcription factor binding|enhancer sequence-specific DNA binding|DNA binding|chromatin binding|transcription cofactor activity|protein binding|enzyme binding|enzyme binding|LIM domain binding|LIM domain binding|LIM domain binding|protein homodimerization activity|protein self-association|,10,-0.7,9.44,10,-0.3,5.26,-0.6,12.5,-12.5,0.0454,0,0,-1,-0.2
ENSMUSG00000020397,MED7,mediator complex subunit 7,nucleus|transcription factor complex|mitochondrion|mediator complex|nuclear membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|stem cell maintenance|",RNA polymerase II transcription cofactor activity|,7,-1.3,5.8,7,1.1,9.54,0.9,12.4,12.4,0.0457,0,0,0.3,1.9
ENSMUSG00000069744,PSMB3,"proteasome (prosome, macropain) subunit, beta type 3",proteasome complex|nucleus|cytoplasm|mitochondrion|Golgi apparatus|proteasome core complex|actin cytoskeleton|extracellular vesicular exosome|,proteolysis|protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,5,-0.8,11.1,6,1.5,14.9,1.5,12.3,12.3,0.046,0,0,-0.8,3
ENSMUSG00000069310,HIST1H3C,"histone cluster 1, H3c",nucleus|extracellular vesicular exosome|,biological_process|,molecular_function|,9,-1.4,15.1,8,-0.1,0.0219,-1.4,12.3,-12.3,0.046,0,0,-3,-0.4
ENSMUSG00000025279,DNASE1L3,deoxyribonuclease 1-like 3,nucleus|nucleus|,"DNA catabolic process, endonucleolytic|DNA catabolic process|apoptotic DNA fragmentation|apoptotic process|developmental programmed cell death|","DNA binding|nuclease activity|endonuclease activity|endodeoxyribonuclease activity|deoxyribonuclease activity|hydrolase activity|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|",10,0.3,0.867,10,1.5,14.9,1.5,12.2,12.2,0.0463,0,0,0.8,3
ENSMUSG00000069308,HIST1H2BP,"histone cluster 1, H2bp",nucleosome|nucleus|chromosome|,None,DNA binding|protein heterodimerization activity|,7,1.2,11,7,0.4,2.85,0.7,11.7,11.7,0.0482,0,0,0.4,1.7
ENSMUSG00000056493,FOXK1,forkhead box K1,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|muscle organ development|cell differentiation|negative regulation of cell growth|negative regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",RNA polymerase II regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.5,7.58,10,-0.4,4.49,-0.5,11.6,-11.6,0.0486,0,0,-0.9,-0.2
ENSMUSG00000028430,NOL6,nucleolar protein family 6 (RNA-associated),condensed nuclear chromosome|nucleus|chromosome|nucleolus|nucleolus|mitochondrion|,biological_process|,RNA binding|poly(A) RNA binding|,10,-0.2,1.27,9,-0.8,13.4,-0.8,11.6,-11.6,0.0486,0,0,-1.6,-0.3
ENSMUSG00000075266,CENPW,centromere protein W,"chromosome, centromeric region|kinetochore|nucleus|chromosome|",mitotic cell cycle|cell cycle|chromosome segregation|mitotic nuclear division|chromosome organization|cell division|kinetochore assembly|,molecular_function|DNA binding|protein heterodimerization activity|,10,1.1,14.5,10,0.1,0.0567,1,11.5,11.5,0.0491,0,0,0.7,2
ENSMUSG00000036442,THAP11,THAP domain containing 11,nucleus|cytoplasm|intercellular bridge|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|zinc ion binding|metal ion binding|,8,0.9,11.4,7,-0.5,1.13,0.9,11.3,11.3,0.0499,0,0,0.4,1.8
ENSMUSG00000039356,EXOSC2,exosome component 2,exosome (RNase complex)|nucleus|cytoplasm|,rRNA processing|positive regulation of cell growth|,molecular_function|RNA binding|,9,0.9,12.1,8,-0.6,2.69,0.8,11.1,11.1,0.0507,0,0,0.4,1.9
ENSMUSG00000046101,MCMDC2,minichromosome maintenance domain containing 2,cellular_component|,DNA replication|biological_process|,molecular_function|DNA binding|ATP binding|,10,0.6,6.38,10,1,5.48,0.9,10.8,10.8,0.0521,0,0,0.3,1.6
ENSMUSG00000024841,EIF1AD,eukaryotic translation initiation factor 1A domain containing,nucleus|intracellular membrane-bounded organelle|intermediate filament cytoskeleton|,translational initiation|,RNA binding|translation initiation factor activity|,8,-1,6.33,10,0.7,9.93,0.5,10.7,10.7,0.0526,0,0,0.1,1.8
ENSMUSG00000028890,MTF1,metal response element binding transcription factor 1,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to oxidative stress|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|response to cadmium ion|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|core promoter binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|histone acetyltransferase binding|metal ion binding|,10,0.8,5.98,10,0.4,6.17,0.4,10.6,10.6,0.0532,0,0,0.2,1.1
ENSMUSG00000022983,SCAF4,SR-related CTD-associated factor 4,nucleus|,mRNA processing|,protein C-terminus binding|poly(A) RNA binding|,9,0.6,7.02,10,1.2,4.9,1,10.5,10.5,0.0537,0,0,0.4,1.7
ENSMUSG00000022641,BBX,bobby sox homolog (Drosophila),nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|bone development|",DNA binding|,10,0.4,2.42,10,0.6,8.7,0.5,10.3,10.3,0.0549,0,0,0.2,1
ENSMUSG00000028099,POLR3C,polymerase (RNA) III (DNA directed) polypeptide C,nucleus|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|,"immune system process|transcription, DNA-templated|positive regulation of interferon-beta production|innate immune response|positive regulation of innate immune response|defense response to virus|",RNA polymerase III activity|DNA binding|DNA-directed RNA polymerase activity|transferase activity|nucleotidyltransferase activity|,9,-0.6,4.1,9,-0.6,6.58,-0.6,10.3,-10.3,0.0549,0,0,-1.5,-0.2
ENSMUSG00000021810,ECD,ecdysoneless homolog (Drosophila),nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell proliferation|regulation of G1/S transition of mitotic cell cycle|",protein binding|,9,-0.3,2.19,9,0.7,10.3,0.7,10.3,10.3,0.0549,0,0,0.3,1.5
ENSMUSG00000041303,GTF3C3,"general transcription factor IIIC, polypeptide 3",transcription factor TFIIIC complex|,biological_process|,molecular_function|,10,-0.8,10.5,10,1.1,9.95,-0.8,10.2,-10.2,0.0555,0,0,-2,1.5
ENSMUSG00000026464,ZC3H11A,zinc finger CCCH type containing 11A,transcription export complex|,transport|poly(A)+ mRNA export from nucleus|mRNA transport|,poly(A) RNA binding|metal ion binding|,10,0.2,0.776,10,1,10.4,0.7,10,10,0.0568,0,0,0.3,1.6
ENSMUSG00000032469,DBR1,debranching enzyme homolog 1 (S. cerevisiae),nucleus|,"RNA splicing, via transesterification reactions|mRNA splicing, via spliceosome|mRNA processing|RNA phosphodiester bond hydrolysis, endonucleolytic|RNA phosphodiester bond hydrolysis, endonucleolytic|","nuclease activity|RNA lariat debranching enzyme activity|RNA lariat debranching enzyme activity|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|poly(A) RNA binding|retroviral 3' processing activity|metal ion binding|",9,-0.5,7.4,9,-0.3,3.1,-0.5,9.95,-9.95,0.0571,0,0,-1.1,-0.2
ENSMUSG00000027304,RTF1,"Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)",nucleus|nucleolus|Cdc73/Paf1 complex|,"negative regulation of transcription from RNA polymerase II promoter|endodermal cell fate commitment|transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|Wnt signaling pathway|histone modification|stem cell maintenance|stem cell maintenance|positive regulation of transcription elongation from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of histone H3-K4 methylation|histone H3-K4 trimethylation|",DNA binding|single-stranded DNA binding|poly(A) RNA binding|,9,0.7,4.84,10,-1.1,12.3,-0.9,9.92,-9.92,0.0571,0,0,-1.9,-0.4
ENSMUSG00000079487,MED12,mediator complex subunit 12,nucleus|membrane|mediator complex|mediator complex|,"neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|heart development|oligodendrocyte development|Schwann cell development|stem cell maintenance|negative regulation of Wnt signaling pathway|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|axis elongation involved in somitogenesis|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II transcription cofactor activity|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|chromatin binding|transcription cofactor activity|transcription coactivator activity|receptor activity|protein binding|beta-catenin binding|protein C-terminus binding|transcription factor binding|protein domain specific binding|thyroid hormone receptor binding|,10,-0.5,4.05,10,-0.8,6.79,-0.6,9.68,-9.68,0.0585,0,0,-2,0.5
ENSMUSG00000034998,FOXN2,forkhead box N2,nucleus|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle cell differentiation|",DNA binding|,10,-0.6,5.98,10,-0.6,3.84,-0.6,9.46,-9.46,0.0601,0,0,-1.2,-0.2
ENSMUSG00000071645,TUT1,"terminal uridylyl transferase 1, U6 snRNA-specific",nucleus|mRNA cleavage and polyadenylation specificity factor complex|nuclear speck|intercellular bridge|,mRNA polyadenylation|mRNA cleavage|mRNA processing|snRNA processing|,nucleotide binding|nucleic acid binding|RNA binding|mRNA 3'-UTR binding|polynucleotide adenylyltransferase activity|ATP binding|transferase activity|nucleotidyltransferase activity|enzyme binding|metal ion binding|RNA uridylyltransferase activity|,8,-0.8,1.17,6,-1.1,9.03,-1.1,9.46,-9.46,0.0601,0,0,-2,-0.6
ENSMUSG00000022536,GLYR1,glyoxylate reductase 1 homolog (Arabidopsis),nucleus|cytoplasm|Golgi apparatus|,pentose-phosphate shunt|oxidation-reduction process|,"DNA binding|phosphogluconate dehydrogenase (decarboxylating) activity|N-ethylmaleimide reductase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|methylated histone binding|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|coenzyme binding|NAD binding|epoxyqueuosine reductase activity|",10,0,0,10,-0.4,10.7,-0.4,9.33,-9.33,0.0614,0,0,-1,-0.2
ENSMUSG00000062417,HIST1H3G,"histone cluster 1, H3g",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,molecular_function|,9,-1.4,9.97,9,-0.3,1.6,-1.3,9.18,-9.18,0.0627,0,0,-2,0.2
ENSMUSG00000037174,ELF2,E74-like factor 2,nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.6,4.13,10,-0.7,5.53,-0.6,9.12,-9.12,0.0631,0,0,-1.3,-0.2
ENSMUSG00000028901,GMEB1,glucocorticoid modulatory element binding protein 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|metal ion binding|,10,0.7,7.59,10,0.3,3.37,0.5,9.02,9.02,0.0638,0,0,0.2,1.2
ENSMUSG00000066042,MED18,mediator complex subunit 18,nucleus|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|biological_process|",RNA polymerase II transcription cofactor activity|,10,0,0,10,-0.8,10.1,-0.7,9,-9,0.064,0,0,-1.6,-0.2
ENSMUSG00000059713,RCAN3,regulator of calcineurin 3,None,calcium-mediated signaling|,nucleotide binding|troponin I binding|,10,0.6,4.43,10,0.6,4.7,0.6,8.77,8.77,0.066,0,0,0.2,1.3
ENSMUSG00000011306,SUGP1,SURP and G patch domain containing 1,nucleus|spliceosomal complex|,RNA processing|mRNA processing|RNA splicing|,nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.1,0.385,10,-0.5,10,-0.4,8.76,-8.76,0.0662,0,0,-1,-0.1
ENSMUSG00000035569,ANKRD11,ankyrin repeat domain 11,nucleus|cytoplasm|plasma membrane|,in utero embryonic development|tissue homeostasis|multicellular organism growth|odontogenesis of dentin-containing tooth|skeletal system morphogenesis|skeletal system morphogenesis|head morphogenesis|face morphogenesis|bone development|,molecular_function|,9,-1.1,4.79,9,-0.5,5.12,-0.5,8.73,-8.73,0.0665,0,0,-1.5,-0.1
ENSMUSG00000020692,NLE1,notchless homolog 1 (Drosophila),nucleus|nucleolus|nucleolus|,inner cell mass cell differentiation|Notch signaling pathway|Notch signaling pathway|ribosomal large subunit biogenesis|negative regulation of mitotic cell cycle|hematopoietic stem cell homeostasis|positive regulation of canonical Wnt signaling pathway|negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|,molecular_function|,6,-0.5,4.68,5,-0.6,4.46,-0.6,8.7,-8.7,0.0669,0,0,-1.7,-0.2
ENSMUSG00000039377,HLX,H2.0-like homeobox,nucleus|,"liver development|transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle tissue development|positive regulation of cell proliferation|cell differentiation|positive regulation of T-helper 1 cell differentiation|positive regulation of T-helper 1 cell differentiation|negative regulation of T-helper 2 cell differentiation|negative regulation of T-helper 2 cell differentiation|positive regulation of organ growth|enteric nervous system development|organ development|embryonic digestive tract morphogenesis|",DNA binding|sequence-specific DNA binding|,10,0.2,1.7,10,0.8,7.73,0.8,8.51,8.51,0.0686,0,0,0.2,1.6
ENSMUSG00000061755,BOD1L,biorientation of chromosomes in cell division 1-like,nucleus|,biological_process|,molecular_function|,9,0.9,7.6,9,0.5,2.37,0.8,8.44,8.44,0.0694,0,0,0.3,1.7
ENSMUSG00000029594,RBM19,RNA binding motif protein 19,nucleus|nucleoplasm|chromosome|nucleolus|cytoplasm|cytoplasm|membrane|,multicellular organismal development|positive regulation of embryonic development|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-1,2.75,10,-1.2,6.09,-1.1,8.42,-8.42,0.0696,0,0,-2,-0.5
ENSMUSG00000041837,PDCD7,programmed cell death 7,nucleus|U12-type spliceosomal complex|,regulation of transcription from RNA polymerase I promoter|apoptotic process|response to glucocorticoid|positive regulation of T cell apoptotic process|positive regulation of apoptotic signaling pathway|,molecular_function|,8,-0.4,0.991,9,1,9.96,0.9,8.39,8.39,0.07,0,0,0.1,2
ENSMUSG00000074656,EIF2S2,"eukaryotic translation initiation factor 2, subunit 2 (beta)",cellular_component|,in utero embryonic development|male germ cell proliferation|translation|translational initiation|male gonad development|,translation initiation factor activity|poly(A) RNA binding|metal ion binding|,10,0.9,8.06,10,1.5,2.45,1.3,8.36,8.36,0.0704,0,0,-0.1,3
ENSMUSG00000038374,RBM8A,RNA binding motif protein 8a,nucleus|nucleus|exon-exon junction complex|catalytic step 2 spliceosome|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of alternative mRNA splicing, via spliceosome|",mRNA binding|poly(A) RNA binding|,4,0.6,4.05,5,0.9,5.43,0.7,8.29,8.29,0.0711,0,0,0.3,1.8
ENSMUSG00000052926,RNASEH2A,"ribonuclease H2, large subunit",nucleus|ribonuclease H2 complex|ribonuclease H2 complex|,"mismatch repair|mismatch repair|RNA catabolic process|RNA metabolic process|RNA phosphodiester bond hydrolysis, endonucleolytic|",nucleic acid binding|RNA binding|nuclease activity|endonuclease activity|RNA-DNA hybrid ribonuclease activity|bidentate ribonuclease III activity|hydrolase activity|metal ion binding|,7,1.1,9.05,8,0.4,1.09,0.8,8.29,8.29,0.0711,0,0,0.4,1.9
ENSMUSG00000040463,MYBBP1A,MYB binding protein (P160) 1a,nucleus|nucleus|nucleolus|nucleolus|cytoplasm|membrane|NLS-dependent protein nuclear import complex|intracellular membrane-bounded organelle|,"osteoblast differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|nucleocytoplasmic transport|respiratory electron transport chain|cellular response to glucose starvation|negative regulation of transcription, DNA-templated|positive regulation of cell cycle arrest|intrinsic apoptotic signaling pathway by p53 class mediator|",DNA binding|DNA-directed DNA polymerase activity|protein binding|transcription factor binding|zinc ion binding|sequence-specific DNA binding|poly(A) RNA binding|,10,-0.7,8.12,9,0.3,0.389,-0.6,8.21,-8.21,0.0719,0,0,-1.6,-0.2
ENSMUSG00000060938,RPL26,ribosomal protein L26,membrane|cytosolic large ribosomal subunit|extracellular vesicular exosome|,rRNA processing|ribosomal large subunit biogenesis|,poly(A) RNA binding|,8,-1,5.28,8,-0.5,4.05,-0.5,8.2,-8.2,0.072,0,0,-1.7,-0.2
ENSMUSG00000038683,PAK1IP1,PAK1 interacting protein 1,nucleus|nucleolus|plasma membrane|,cell proliferation|negative regulation of signal transduction|palate development|,protein binding|,10,-0.6,7.68,8,-0.7,0.702,-0.6,8.13,-8.13,0.0728,0,0,-1.6,-0.2
ENSMUSG00000021714,CENPK,centromere protein K,"chromosome, centromeric region|kinetochore|nucleus|chromosome|",positive regulation of transcription from RNA polymerase II promoter|,protein binding|,10,0.6,2.15,8,0.7,6.23,0.7,7.94,7.94,0.0749,0,0,0.1,1.8
ENSMUSG00000030512,SNRPA1,small nuclear ribonucleoprotein polypeptide A',nucleus|spliceosomal complex|virion|viral nucleocapsid|ribonucleoprotein complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,RNA binding|poly(A) RNA binding|,8,-1.2,8.05,8,-0.6,1.49,-0.7,7.83,-7.83,0.0761,0,0,-2,-0.1
ENSMUSG00000003847,NFAT5,nuclear factor of activated T cells 5,nucleus|cytoplasm|,"cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of gene expression|positive regulation of transcription from RNA polymerase II promoter|regulation of calcineurin-NFAT signaling cascade|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,0.3,0.98,10,0.7,7.78,0.6,7.77,7.77,0.077,0,0,0.1,1.5
ENSMUSG00000039449,PRPF18,PRP18 pre-mRNA processing factor 18 homolog (yeast),cellular_component|nucleus|spliceosomal complex|,mRNA processing|RNA splicing|,potassium channel inhibitor activity|,8,-0.7,5.67,9,-0.4,3.24,-0.4,7.69,-7.69,0.0781,0,0,-1.2,-0.1
ENSMUSG00000022336,EIF3E,"eukaryotic translation initiation factor 3, subunit E",nucleus|cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|membrane|PML body|extracellular vesicular exosome|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|translation|translational initiation|translational initiation|",translation initiation factor activity|translation initiation factor activity|poly(A) RNA binding|protein N-terminus binding|,8,-0.6,2.24,8,-0.5,5.82,-0.5,7.68,-7.68,0.0783,0,0,-1.6,0.3
ENSMUSG00000031157,PQBP1,polyglutamine binding protein 1,nucleus|nucleus|cytoplasm|cytoplasm|cytoplasmic stress granule|nuclear speck|neuronal ribonucleoprotein granule|,"alternative mRNA splicing, via spliceosome|alternative mRNA splicing, via spliceosome|transcription, DNA-templated|regulation of transcription, DNA-templated|neuron projection development|stress granule assembly|regulation of RNA splicing|regulation of dendrite morphogenesis|",ribonucleoprotein complex binding|,10,0.3,2.82,10,0.4,5.25,0.4,7.67,7.67,0.0784,0,0,0.1,1
ENSMUSG00000039826,TRUB2,TruB pseudouridine (psi) synthase homolog 2 (E. coli),cellular_component|,pseudouridine synthesis|RNA processing|tRNA processing|biological_process|RNA modification|,RNA binding|pseudouridine synthase activity|isomerase activity|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|poly(A) RNA binding|baruol synthase activity|,9,0.5,2.07,9,-0.9,8.52,-0.7,7.66,-7.66,0.0786,0,0,-2,1
ENSMUSG00000058881,ZFP516,zinc finger protein 516,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.3,1.24,10,-0.4,6.89,-0.4,7.64,-7.64,0.0789,0,0,-1,-0.1
ENSMUSG00000040148,HMX3,H6 homeobox 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|brain development|embryo implantation|cell differentiation|inner ear morphogenesis|inner ear morphogenesis|neuromuscular process controlling balance|maternal process involved in female pregnancy|",DNA binding|sequence-specific DNA binding|,10,-0.4,2.5,10,-0.6,5.72,-0.5,7.62,-7.62,0.0793,0,0,-1.3,-0.1
ENSMUSG00000025959,KLF7,Kruppel-like factor 7 (ubiquitous),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|axonogenesis|axon guidance|positive regulation of transcription, DNA-templated|dendrite morphogenesis|",nucleic acid binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,9,1.4,10.5,10,-0.2,0.679,1.4,7.49,7.49,0.081,0,0,0.2,2
ENSMUSG00000008976,GABPA,"GA repeat binding protein, alpha",nuclear chromatin|nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of megakaryocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0.6,3.12,9,-1.1,9.09,0.6,7.48,7.48,0.0811,0,0,-1.5,3
ENSMUSG00000069272,HIST1H2AE,"histone cluster 1, H2ae",nucleus|extracellular vesicular exosome|,biological_process|,enzyme binding|,6,-0.7,6.54,6,0.7,7.24,0.7,7.47,7.47,0.0814,0,0,-1.1,2
ENSMUSG00000031848,LSM4,"LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)",nucleus|nucleoplasm|spliceosomal complex|cytoplasm|ribonucleoprotein complex|,mRNA processing|biological_process|RNA splicing|,RNA binding|poly(A) RNA binding|,9,0.6,2.33,9,-1,6.67,-1,7.46,-7.46,0.0815,0,0,-2,1.1
ENSMUSG00000002107,CELF2,"CUGBP, Elav-like family member 2",nucleus|nucleus|cytoplasm|,mRNA splice site selection|mRNA processing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.8,4.15,10,0.9,9.15,0.8,7.31,7.31,0.0838,0,0,-0.6,2
ENSMUSG00000054003,TDRD9,tudor domain containing 9,nucleus|cytoplasm|piP-body|,meiotic nuclear division|male meiosis|multicellular organismal development|spermatogenesis|fertilization|cell differentiation|gene silencing by RNA|piRNA metabolic process|DNA methylation involved in gamete generation|,nucleotide binding|nucleic acid binding|helicase activity|protein binding|ATP binding|hydrolase activity|,10,0,0,10,-1.1,10.6,-1.1,7.27,-7.27,0.0843,0,0,-1.9,-0.3
ENSMUSG00000031079,ZFP300,zinc finger protein 300,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,1,10.5,10,-0.2,1.02,1,7.18,7.18,0.0855,0,0,0.3,1.9
ENSMUSG00000022419,DEPTOR,DEP domain containing MTOR-interacting protein,intracellular|,negative regulation of protein kinase activity|negative regulation of TOR signaling|intracellular signal transduction|negative regulation of cell size|regulation of extrinsic apoptotic signaling pathway|,None,9,0.5,3.43,9,1,5.26,0.5,7.15,7.15,0.0861,0,0,0.1,1.6
ENSMUSG00000036572,UPF3B,UPF3 regulator of nonsense transcripts homolog B (yeast),nucleus|cytoplasm|exon-exon junction complex|exon-exon junction complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|response to unfolded protein|positive regulation of translation|",mRNA binding|poly(A) RNA binding|,9,-0.6,4.55,9,-0.3,3.3,-0.3,7.12,-7.12,0.0865,0,0,-1.1,-0.1
ENSMUSG00000036181,HIST1H1C,"histone cluster 1, H1c",nucleosome|nucleus|chromosome|nuclear euchromatin|,nucleosome assembly|nucleosome positioning|,DNA binding|protein binding|chromatin DNA binding|poly(A) RNA binding|,10,0.2,2.17,10,0.4,5.33,0.4,7.02,7.02,0.0885,0,0,0.1,0.9
ENSMUSG00000043602,ZFP3,zinc finger protein 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.5,2.99,10,0.4,4.48,0.5,6.97,6.97,0.0895,0,0,0.1,1.2
ENSMUSG00000034321,EXOSC1,exosome component 1,exosome (RNase complex)|nucleus|nucleolus|cytoplasm|,rRNA processing|RNA processing|,RNA binding|protein binding|,8,0.9,3.7,9,0.5,3.78,0.6,6.95,6.95,0.0898,0,0,-0.8,1.9
ENSMUSG00000045817,ZFP36L2,"zinc finger protein 36, C3H type-like 2",nucleus|cytoplasm|,"nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|mRNA catabolic process|hemopoiesis|T cell differentiation in thymus|somatic stem cell maintenance|regulation of mRNA stability|somatic stem cell division|definitive hemopoiesis|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|negative regulation of stem cell differentiation|",DNA binding|RNA binding|AU-rich element binding|mRNA 3'-UTR AU-rich region binding|poly(A) RNA binding|metal ion binding|,10,0.6,5.22,10,0.6,1.96,0.6,6.88,6.88,0.0912,0,0,0.1,1.4
ENSMUSG00000068391,CHRAC1,chromatin accessibility complex 1,cellular_component|intracellular|nucleus|,biological_process|,DNA binding|DNA-directed DNA polymerase activity|protein binding|transferase activity|nucleotidyltransferase activity|sequence-specific DNA binding|protein heterodimerization activity|,10,0.5,6.31,10,0.2,1.48,0.4,6.83,6.83,0.0921,0,0,0.1,1.1
ENSMUSG00000071256,ZFP213,zinc finger protein 213,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|metal ion binding|,10,0.4,3.36,10,0.4,3.8,0.4,6.82,6.82,0.0922,0,0,0,1.4
ENSMUSG00000069312,HIST1H3H,"histone cluster 1, H3h",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,molecular_function|,8,-0.8,4.75,7,-0.7,2.45,-0.8,6.8,-6.8,0.0927,0,0,-1.7,-0.2
ENSMUSG00000001823,HOXD12,homeobox D12,nucleus|transcription factor complex|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|embryonic digit morphogenesis|",DNA binding|protein binding|sequence-specific DNA binding|,10,0.9,3.05,10,1.1,4.29,1,6.65,6.65,0.0958,0,0,-0.1,2
ENSMUSG00000023104,RFC2,replication factor C (activator 1) 2,nucleus|DNA replication factor C complex|,DNA replication|,nucleotide binding|DNA binding|ATP binding|,7,-0.8,3.43,7,0.5,4.36,-0.9,6.53,-6.53,0.098,0,0,-2,0.8
ENSMUSG00000027246,ELL3,elongation factor RNA polymerase II-like 3,nucleus|nucleus|transcription elongation factor complex|,"transcription, DNA-templated|DNA-templated transcription, elongation|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription elongation from RNA polymerase II promoter|regulation of epithelial to mesenchymal transition|positive regulation of DNA-templated transcription, elongation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|stem cell differentiation|positive regulation of neurogenesis|negative regulation of signal transduction by p53 class mediator|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of neural precursor cell proliferation|",protein binding|enhancer binding|,10,-0.1,0.388,10,-0.7,7.91,-0.4,6.43,-6.43,0.1,0,0,-1.6,0.1
ENSMUSG00000061458,NOL10,nucleolar protein 10,cellular_component|nucleus|,biological_process|,poly(A) RNA binding|,10,0.4,2.91,9,-1.1,8.66,-1,6.37,-6.37,0.101,0,0,-2,0.3
ENSMUSG00000079428,TCEAL7,transcription elongation factor A (SII)-like 7,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of NF-kappaB transcription factor activity|negative regulation of transcription, DNA-templated|",None,10,1.4,8.63,10,-0.3,2.07,1.4,6.32,6.32,0.102,0,0,-0.1,2
ENSMUSG00000037188,GRHL3,grainyhead-like 3 (Drosophila),nucleus|,"establishment of planar polarity|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|pattern specification process|ectoderm development|central nervous system development|epidermis development|positive regulation of gene expression|positive regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|wound healing|wound healing|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|eyelid development in camera-type eye|cochlea morphogenesis|planar cell polarity pathway involved in neural tube closure|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|protein binding|,9,-0.7,3.58,9,-0.5,3.14,-0.5,6.28,-6.28,0.103,0,0,-1.6,-0.1
ENSMUSG00000027593,RALY,hnRNP-associated with lethal yellow,nucleus|spliceosomal complex|ribonucleoprotein complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.3,0.38,10,-0.6,6.87,-0.5,6.26,-6.26,0.104,0,0,-1.3,0
ENSMUSG00000079716,MAP3K4,mitogen-activated protein kinase kinase kinase 4,cytoplasm|cytoplasm|,MAPK cascade|activation of MAPKK activity|placenta development|protein phosphorylation|response to UV-C|regulation of gene expression|phosphorylation|male germ-line sex determination|intracellular signal transduction|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|determination of dorsal identity|chorionic trophoblast cell differentiation|positive regulation of p38MAPK cascade|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.3,2.52,10,0.3,4.03,0.3,6.25,6.25,0.104,0,0,0,0.9
ENSMUSG00000038697,TAF5L,"TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor",nucleus|STAGA complex|transcription factor TFTC complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|histone H3 acetylation|regulation of RNA biosynthetic process|",transcription coactivator activity|histone acetyltransferase activity|,10,1.2,4.26,10,1.2,2.22,1.2,6.17,6.17,0.106,0,0,0.4,2
ENSMUSG00000001657,HOXC8,homeobox C8,nucleus|nucleus|microtubule cytoskeleton|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|neuron differentiation|skeletal system morphogenesis|skeletal system morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.4,4.35,10,-0.4,2.05,-0.4,6.1,-6.1,0.108,0,0,-1.3,0
ENSMUSG00000057649,BRD9,bromodomain containing 9,cellular_component|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|chromatin modification|",lysine-acetylated histone binding|,10,1.3,8.13,10,0.2,0.912,0.7,6.08,6.08,0.108,0,0,0.2,1.9
ENSMUSG00000035666,GTF3C4,"general transcription factor IIIC, polypeptide 4",transcription factor TFIIIC complex|nucleus|,"transcription, DNA-templated|biological_process|","molecular_function|DNA binding|histone acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,-0.2,1.87,10,-0.5,4.86,-0.5,6.08,-6.08,0.108,0,0,-1.4,0.2
ENSMUSG00000021569,TRIP13,thyroid hormone receptor interactor 13,male germ cell nucleus|,oocyte maturation|double-strand break repair|meiotic nuclear division|synaptonemal complex assembly|reciprocal meiotic recombination|male meiosis I|female meiosis I|spermatogenesis|spermatid development|cell differentiation|oogenesis|,nucleotide binding|protein binding|ATP binding|identical protein binding|,10,0.5,2.78,10,0.6,3.84,0.5,6.07,6.07,0.108,0,0,0,1.3
ENSMUSG00000060950,TRMT61A,tRNA methyltransferase 61A,cellular_component|nucleus|tRNA (m1A) methyltransferase complex|,tRNA processing|biological_process|tRNA methylation|methylation|,molecular_function|methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|transferase activity|,7,-0.9,8.73,7,0.1,0.0863,-0.8,6.06,-6.06,0.109,0,0,-2,-0.3
ENSMUSG00000021418,RPP40,ribonuclease P 40 subunit,nucleus|nucleolar ribonuclease P complex|,"tRNA 5'-leader removal|tRNA processing|RNA phosphodiester bond hydrolysis, endonucleolytic|",ribonuclease P activity|hydrolase activity|,7,-0.5,3.76,8,-0.9,3.63,-0.6,6.05,-6.05,0.109,0,0,-1.9,-0.1
ENSMUSG00000028483,SNAPC3,"small nuclear RNA activating complex, polypeptide 3",nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|,9,0.6,4.75,8,0.4,2.32,0.5,6.04,6.04,0.109,0,0,-0.1,1.3
ENSMUSG00000043760,PKHD1,polycystic kidney and hepatic disease 1,cytoplasm|centrosome|apical plasma membrane|ciliary basal body|perinuclear region of cytoplasm|extracellular vesicular exosome|primary cilium|mitotic spindle|,kidney development|cellular calcium ion homeostasis|positive regulation of cell proliferation|regulation of centrosome duplication|regulation of TOR signaling|negative regulation of NF-kappaB transcription factor activity|cilium assembly|negative regulation of apoptotic process|negative regulation of protein kinase B signaling|regulation of ERK1 and ERK2 cascade|,protein binding|,10,-1,3.58,10,-0.8,2.86,-0.9,5.96,-5.96,0.111,0,0,-2,-0.2
ENSMUSG00000049184,PURG,purine-rich element binding protein G,cellular_component|nucleus|,biological_process|,DNA binding|poly(A) RNA binding|,10,-1.2,4.61,10,1.5,8.86,0.2,5.95,5.95,0.111,0,0,-1,3
ENSMUSG00000031226,PBDC1,polysaccharide biosynthesis domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.6,8.39,10,0,0,-0.6,5.87,-5.87,0.113,0,0,-1.9,-0.2
ENSMUSG00000055760,GEMIN6,gem (nuclear organelle) associated protein 6,nucleus|nucleoplasm|cytoplasm|cytosol|nuclear body|SMN complex|SMN-Sm protein complex|,spliceosomal complex assembly|spliceosomal snRNP assembly|mRNA processing|RNA splicing|,protein binding|,8,0.8,5.86,7,0.3,2.47,0.5,5.86,5.86,0.113,0,0,-0.3,2
ENSMUSG00000022529,ZFP263,zinc finger protein 263,nucleus|cytoplasm|microtubule cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|metal ion binding|,10,1.3,7.43,10,0.2,0.869,0.7,5.84,5.84,0.114,0,0,0.1,1.9
ENSMUSG00000041890,GIT2,G protein-coupled receptor kinase-interactor 2,nucleoplasm|,phosphorylation|regulation of ARF GTPase activity|behavioral response to pain|,GTPase activator activity|protein binding|ARF GTPase activator activity|zinc ion binding|kinase activity|transferase activity|metal ion binding|,10,-0.8,0.0014,10,0.4,7.04,0.4,5.82,5.82,0.115,0,0,-0.2,1.4
ENSMUSG00000020982,NEMF,nuclear export mediator factor,intracellular|cell|nucleus|,nuclear export|,molecular_function|,10,-0.3,0.788,10,-1.1,7.91,-1,5.82,-5.82,0.115,0,0,-2,0.1
ENSMUSG00000002679,MED6,mediator complex subunit 6,nucleus|membrane|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|stem cell maintenance|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|DNA binding|transcription coactivator activity|protein binding|transcription factor binding|,8,0.6,3.35,8,-0.8,7.41,-0.8,5.75,-5.75,0.116,0,0,-2,0.7
ENSMUSG00000046865,FBL,fibrillarin,dense fibrillar component|granular component|nucleus|nucleolus|nucleolus|nucleolus|Cajal body|Cajal body|Cajal body|membrane|ribonucleoprotein complex|extracellular vesicular exosome|,osteoblast differentiation|rRNA processing|RNA processing|tRNA processing|snoRNA metabolic process|methylation|histone glutamine methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|snoRNA binding|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|histone-glutamine methyltransferase activity|",10,0.4,3.97,10,0.2,2.01,0.4,5.67,5.67,0.119,0,0,0,1.2
ENSMUSG00000029402,SNRNP35,small nuclear ribonucleoprotein 35 (U11/U12),nucleus|spliceosomal complex|U12-type spliceosomal complex|,mRNA processing|biological_process|RNA splicing|,nucleotide binding|molecular_function|nucleic acid binding|RNA binding|,8,0,0,9,-1.2,8.48,-1.2,5.62,-5.62,0.12,0,0,-2,-0.3
ENSMUSG00000022191,DROSHA,"drosha, ribonuclease type III",nucleus|,"RNA processing|regulation of gene expression|miRNA metabolic process|rRNA catabolic process|primary miRNA processing|pre-miRNA processing|ribosome biogenesis|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|RNA phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, endonucleolytic|RNA phosphodiester bond hydrolysis, endonucleolytic|",lipopolysaccharide binding|RNA binding|nuclease activity|endonuclease activity|endoribonuclease activity|ribonuclease III activity|protein binding|hydrolase activity|poly(A) RNA binding|metal ion binding|,10,0.1,0.727,10,1.1,7.49,0.7,5.56,5.56,0.122,0,0,0.2,1.9
ENSMUSG00000025782,TAF3,"TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|transcription factor TFIID complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of sequence-specific DNA binding transcription factor activity|maintenance of protein location in nucleus|",p53 binding|protein binding|zinc ion binding|metal ion binding|,8,-0.5,0.621,8,-0.7,5.24,-0.6,5.56,-5.56,0.122,0,0,-1.8,0.1
ENSMUSG00000089824,RBM12,RNA binding motif protein 12,nucleus|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,4,0.4,2.99,4,0.5,2.86,0.4,5.46,5.46,0.125,0,0,-0.1,1.8
ENSMUSG00000029345,TFIP11,tuftelin interacting protein 11,proteinaceous extracellular matrix|intracellular|nucleus|spliceosomal complex|cytoplasm|nuclear speck|U2-type post-mRNA release spliceosomal complex|catalytic step 2 spliceosome|,"spliceosomal complex disassembly|spliceosomal complex disassembly|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|cell differentiation|extracellular matrix organization|biomineral tissue development|",nucleic acid binding|DNA binding|protein binding|,10,0.5,7.26,10,-0.9,8.2,0.4,5.46,5.46,0.125,0,0,-1.8,1.1
ENSMUSG00000037364,SRRT,serrate RNA effector molecule homolog (Arabidopsis),nucleus|nucleoplasm|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell proliferation|gene silencing by RNA|primary miRNA processing|primary miRNA processing|neuronal stem cell maintenance|",DNA binding|protein binding|poly(A) RNA binding|,10,-0.8,4.67,10,-1.3,2.61,-0.9,5.46,-5.46,0.125,0,0,-2,-0.3
ENSMUSG00000028053,ASH1L,"ash1 (absent, small, or homeotic)-like (Drosophila)",nucleus|chromosome|cytoplasm|Golgi apparatus|tight junction|cell junction|extracellular vesicular exosome|,"negative regulation of acute inflammatory response|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|methylation|interleukin-6 production|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of MAPK cascade|positive regulation of transcription from RNA polymerase II promoter|negative regulation of inflammatory response|histone H3-K4 methylation|",DNA binding|chromatin binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H3-K4 specific)|metal ion binding|,10,-0.2,0.79,10,-0.5,5.41,-0.4,5.42,-5.42,0.126,0,0,-1.3,0.2
ENSMUSG00000059309,HIST1H3F,"histone cluster 1, H3f",nucleus|nucleus|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-1.1,7.61,10,0.6,1.79,-1,5.4,-5.4,0.127,0,0,-2,0.7
ENSMUSG00000047003,ZFP41,zinc finger protein 41,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|biological_process|cell differentiation|",nucleic acid binding|DNA binding|metal ion binding|,10,-1.1,8.5,10,0,0,-1.1,5.33,-5.33,0.129,0,0,-2,-0.3
ENSMUSG00000033964,ZBTB41,zinc finger and BTB domain containing 41 homolog,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.5,1.36,9,-0.5,6.86,-0.4,5.3,-5.3,0.13,0,0,-1.5,0.7
ENSMUSG00000041645,DDX24,DEAD (Asp-Glu-Ala-Asp) box polypeptide 24,nucleolus|membrane|,None,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,8,-0.5,5.03,9,0.5,1.42,-0.6,5.28,-5.28,0.13,0,0,-1.5,0.7
ENSMUSG00000004356,UTP20,"UTP20, small subunit (SSU) processome component, homolog (yeast)",nucleus|nucleolus|,rRNA processing|,poly(A) RNA binding|,8,-0.3,1.48,9,-0.4,4.04,-0.4,5.25,-5.25,0.131,0,0,-1.4,0.4
ENSMUSG00000061482,HIST1H4D,"histone cluster 1, H4d",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,9,-0.4,3.02,9,-1,4.63,-0.6,5.19,-5.19,0.134,0,0,-2,0
ENSMUSG00000060152,POP5,"processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)",ribonuclease MRP complex|nucleus|nucleolar ribonuclease P complex|,"rRNA processing|tRNA processing|RNA metabolic process|RNA phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, endonucleolytic|",ribonuclease MRP activity|ribonuclease P activity|ribonuclease activity|hydrolase activity|,10,0.5,7.17,9,-1.4,2.66,0.5,5.19,5.19,0.134,0,0,-1.2,2
ENSMUSG00000098022,ZFP82,zinc finger protein 82,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.4,1.93,10,-0.5,3.6,-0.4,5.15,-5.15,0.135,0,0,-1.5,0.4
ENSMUSG00000022538,LSG1,large subunit GTPase 1 homolog (S. cerevisiae),nucleus|cytoplasm|endoplasmic reticulum|cytosol|Cajal body|membrane|,GTP catabolic process|GTP catabolic process|transport|protein transport|ribosome biogenesis|nuclear export|,"nucleotide binding|GTPase activity|GTPase activity|thiamine-pyrophosphatase activity|GTP binding|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|",9,-0.5,5.22,10,-0.3,1.37,-0.4,5.13,-5.13,0.136,0,0,-1.3,0.5
ENSMUSG00000063888,RPL7L1,ribosomal protein L7-like 1,ribosome|ribonucleoprotein complex|,None,poly(A) RNA binding|,10,-0.3,4.12,10,-0.3,1.26,-0.3,5.12,-5.12,0.136,0,0,-1.4,0.2
ENSMUSG00000042167,PAPD4,PAP associated domain containing 4,nucleus|cytoplasm|,hematopoietic progenitor cell differentiation|mRNA processing|RNA polyadenylation|histone mRNA catabolic process|,nucleotide binding|polynucleotide adenylyltransferase activity|protein binding|ATP binding|transferase activity|metal ion binding|,10,0.6,3.25,10,0.4,2.66,0.3,5.1,5.1,0.137,0,0,0,1.4
ENSMUSG00000095253,ZFP799,zinc finger protein 799,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,1.1,8.05,10,-0.2,0.285,1.1,5.1,5.1,0.137,0,0,0,2
ENSMUSG00000060630,ZFP735,zinc finger protein 735,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.2,1.15,9,0.5,4.83,0.5,5.09,5.09,0.137,0,0,-0.5,1.4
ENSMUSG00000028187,RPF1,ribosome production factor 1 homolog (S. cerevisiae),nucleus|nucleolus|,rRNA processing|biological_process|ribosome biogenesis|,RNA binding|rRNA binding|poly(A) RNA binding|,10,-0.2,0.714,10,-0.7,5,-0.7,5,-5,0.14,0,0,-1.8,0.3
ENSMUSG00000020273,PAPOLG,poly(A) polymerase gamma,nucleus|nucleus|cytoplasm|membrane|,mRNA polyadenylation|mRNA processing|RNA 3'-end processing|RNA polyadenylation|,nucleotide binding|RNA binding|polynucleotide adenylyltransferase activity|polynucleotide adenylyltransferase activity|ATP binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,0.4,3.38,10,0.3,2.12,0.3,5,5,0.14,0,0,-0.1,1
ENSMUSG00000048930,TADA3,transcriptional adaptor 3,intracellular|nucleus|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|STAGA complex|STAGA complex|transcription factor TFTC complex|mitotic spindle|,"regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|mitotic nuclear division|positive regulation of gene expression|regulation of histone deacetylation|regulation of protein stability|histone H3 acetylation|positive regulation of transcription, DNA-templated|regulation of tubulin deacetylation|regulation of RNA biosynthetic process|",transcription coactivator activity|histone acetyltransferase activity|protein binding|ligand-dependent nuclear receptor binding|protein domain specific binding|ligand-dependent nuclear receptor transcription coactivator activity|,10,0.1,0.499,10,0.3,5.29,0.3,4.98,4.98,0.141,0,0,-0.8,1.1
ENSMUSG00000062761,ZFP512,zinc finger protein 512,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0,0,10,-1.1,8.21,-1.1,4.95,-4.95,0.142,0,0,-2,-0.2
ENSMUSG00000072623,ZFP9,zinc finger protein 9,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.4,3.1,10,-0.4,2.07,-0.4,4.89,-4.89,0.145,0,0,-1.1,0.1
ENSMUSG00000030752,KDM8,lysine (K)-specific demethylase 8,nucleus|,"G2/M transition of mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|chromatin modification|positive regulation of transcription, DNA-templated|oxidation-reduction process|histone H3-K36 demethylation|",chromatin binding|oxidoreductase activity|metal ion binding|dioxygenase activity|histone demethylase activity (H3-K36 specific)|,10,0.4,3.36,10,0.4,1.78,0.4,4.87,4.87,0.145,0,0,0,1.2
ENSMUSG00000021024,PSMA6,"proteasome (prosome, macropain) subunit, alpha type 6","proteasome complex|cytoplasmic mRNA processing body|nucleus|cytoplasm|cytoplasm|proteasome core complex|polysome|nuclear matrix|proteasome core complex, alpha-subunit complex|myofibril|sarcomere|extracellular vesicular exosome|",proteolysis|ubiquitin-dependent protein catabolic process|skeletal muscle tissue development|positive regulation of NF-kappaB transcription factor activity|proteolysis involved in cellular protein catabolic process|,RNA binding|RNA binding|endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|NF-kappaB binding|,8,-1.2,7.48,7,0.6,0.87,-1.2,4.85,-4.85,0.146,0,0,-2,0.7
ENSMUSG00000029504,DDX51,DEAD (Asp-Glu-Ala-Asp) box polypeptide 51,nucleus|membrane|,rRNA processing|biological_process|ribosome biogenesis|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,-0.2,0.448,10,-0.9,6.96,-0.8,4.84,-4.84,0.146,0,0,-1.9,-0.1
ENSMUSG00000043445,PGP,phosphoglycolate phosphatase,cellular_component|,carbohydrate metabolic process|metabolic process|dephosphorylation|peptidyl-tyrosine dephosphorylation|,"magnesium ion binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|phosphoglycolate phosphatase activity|hydrolase activity|phosphatase activity|metal ion binding|nucleotide phosphatase activity, acting on free nucleotides|",10,-0.7,7.41,10,0,0,-0.7,4.83,-4.83,0.147,0,0,-1.6,0
ENSMUSG00000072995,CPXCR1,"CPX chromosome region, candidate 1",cellular_component|,biological_process|,molecular_function|,10,-0.2,2.23,10,-0.3,3.12,-0.3,4.78,-4.78,0.149,0,0,-1,0.2
ENSMUSG00000031635,ANXA10,annexin A10,mitochondrion|,None,calcium ion binding|calcium-dependent phospholipid binding|,10,-0.4,2.01,10,-0.4,3.03,-0.4,4.76,-4.76,0.15,0,0,-1.2,0.2
ENSMUSG00000030213,ATF7IP,activating transcription factor 7 interacting protein,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|ATP catabolic process|DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|regulation of RNA polymerase II transcriptional preinitiation complex assembly|",transcription corepressor activity|ATPase activity|,10,0.9,7.32,10,-1.2,4.13,0.8,4.66,4.66,0.154,0,0,-1.5,2
ENSMUSG00000064037,GPN1,GPN-loop GTPase 1,cytoplasm|,biological_process|,nucleotide binding|GTP binding|,10,0.7,1.8,10,-0.4,3.28,0.6,4.58,4.58,0.157,0,0,-1,1.4
ENSMUSG00000034032,RPAP1,RNA polymerase II associated protein 1,nucleus|RNA polymerase complex|,"transcription, DNA-templated|",DNA binding|DNA-directed RNA polymerase activity|transferase activity|nucleotidyltransferase activity|,9,1.2,1.22,10,-0.6,5.37,-0.5,4.48,-4.48,0.162,0,0,-1.5,1.5
ENSMUSG00000071359,TBPL1,TATA box binding protein-like 1,nucleus|transcription factor TFIIA complex|cytoplasm|,"acrosome assembly|dTTP biosynthetic process|DNA-templated transcription, initiation|spermatogenesis|spermatogenesis|spermatid nucleus differentiation|",DNA binding|protein binding|,10,-0.5,5.5,10,0.5,0.624,-0.5,4.45,-4.45,0.163,0,0,-1.3,1
ENSMUSG00000036733,RBM42,RNA binding motif protein 42,nucleus|cytoplasm|,None,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.4,5.31,10,-0.2,1,0.4,4.42,4.42,0.165,0,0,-0.7,1.7
ENSMUSG00000027580,HELZ2,"helicase with zinc finger 2, transcriptional coactivator",nucleus|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",nucleotide binding|DNA binding|helicase activity|ATP binding|hydrolase activity|ligand-dependent nuclear receptor transcription coactivator activity|poly(A) RNA binding|metal ion binding|,10,-0.3,2,10,-0.4,2.8,-0.3,4.42,-4.42,0.165,0,0,-1.2,0.1
ENSMUSG00000027831,VEPH1,ventricular zone expressed PH domain-containing 1,cellular_component|plasma membrane|membrane|,biological_process|,molecular_function|,10,0,0,10,-1.1,7.48,-1.1,4.4,-4.4,0.166,0,0,-2,0.2
ENSMUSG00000035851,YTHDC1,YTH domain containing 1,nucleus|nucleoplasm|nuclear body|,"mRNA splicing, via spliceosome|mRNA splice site selection|mRNA processing|RNA splicing|",RNA binding|poly(A) RNA binding|,10,0.5,3.34,10,-0.6,6.88,-0.6,4.38,-4.38,0.167,0,0,-1.8,0.6
ENSMUSG00000024800,RPP30,ribonuclease P/MRP 30 subunit,cellular_component|nucleus|,tRNA processing|biological_process|,catalytic activity|ribonuclease P activity|ribonuclease activity|hydrolase activity|poly(A) RNA binding|,10,-1,2.79,10,-0.3,2.97,-0.4,4.37,-4.37,0.168,0,0,-1.9,0.7
ENSMUSG00000024383,MAP3K2,mitogen-activated protein kinase kinase kinase 2,nucleus|cytoplasm|cytosol|,"MAPK cascade|activation of MAPKK activity|protein phosphorylation|protein phosphorylation|phosphorylation|positive regulation of transcription, DNA-templated|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|metal ion binding|",10,0.5,1.82,10,0.3,3.08,0.3,4.34,4.34,0.169,0,0,-0.3,1.2
ENSMUSG00000029701,RBM28,RNA binding motif protein 28,nucleus|spliceosomal complex|nucleolus|,mRNA processing|biological_process|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.7,3.53,10,-0.3,1.26,-0.7,4.29,-4.29,0.172,0,0,-1.9,0.6
ENSMUSG00000069274,HIST1H4F,"histone cluster 1, H4f",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,10,-1,3.34,10,0.5,4.66,0.4,4.28,4.28,0.172,0,0,-1.8,1.1
ENSMUSG00000030127,COPS7A,"COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)",nucleus|cytoplasm|COP9 signalosome|COP9 signalosome|,cullin deneddylation|cullin deneddylation|,molecular_function|,10,0.3,2.59,10,0.3,1.95,0.3,4.28,4.28,0.172,0,0,-0.2,1.2
ENSMUSG00000021047,NOVA1,neuro-oncological ventral antigen 1,nucleus|nucleus|nucleolus|intracellular membrane-bounded organelle|,"mRNA splicing, via spliceosome|mRNA splicing, via spliceosome|nervous system development|regulation of RNA metabolic process|",RNA binding|mRNA binding|protein binding|poly(A) RNA binding|,10,-0.6,1.79,10,-0.4,2.95,-0.4,4.27,-4.27,0.173,0,0,-1.4,0.4
ENSMUSG00000036672,CENPT,centromere protein T,"chromosome, centromeric region|kinetochore|nucleus|chromosome|cytoplasm|nuclear membrane|",mitotic cell cycle|cell cycle|chromosome segregation|mitotic nuclear division|chromosome organization|cell division|kinetochore assembly|,molecular_function|DNA binding|protein heterodimerization activity|,10,-0.4,3.17,10,0.4,2.86,0.4,4.25,4.25,0.174,0,0,-0.8,1.5
ENSMUSG00000032864,RAG2,recombination activating gene 2,nucleus|,B cell lineage commitment|pre-B cell allelic exclusion|B cell homeostatic proliferation|T cell lineage commitment|DNA recombination|chromatin modification|B cell differentiation|T cell differentiation|T cell differentiation in thymus|V(D)J recombination|V(D)J recombination|positive regulation of organ growth|positive regulation of organ growth|,"DNA binding|chromatin binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|zinc ion binding|methylated histone binding|phosphatidylinositol binding|phosphatidylinositol-3,4-bisphosphate binding|metal ion binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0.7,1.28,10,-0.5,4.66,-0.3,4.16,-4.16,0.178,0,0,-1.4,1
ENSMUSG00000031393,MECP2,methyl CpG binding protein 2,nuclear chromatin|heterochromatin|heterochromatin|heterochromatin|extracellular space|cell|nucleus|nucleus|cytoplasm|cytosol|cytosol|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|behavioral fear response|response to hypoxia|startle response|neurological system process involved in regulation of systemic arterial blood pressure|regulation of respiratory gaseous exchange by neurological system process|inositol metabolic process|mitochondrial electron transport, ubiquinol to cytochrome c|chromatin silencing|regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|glutamine metabolic process|cellular biogenic amine metabolic process|synaptic transmission|synapse assembly|brain development|respiratory gaseous exchange|learning|memory|long-term memory|protein localization|glucocorticoid metabolic process|positive regulation of cell proliferation|adult locomotory behavior|visual learning|pathogenesis|embryo development|post-embryonic development|regulation of gene expression|dendrite development|histone methylation|histone acetylation|proprioception|sensory perception of pain|cerebellum development|ventricular system development|neuron differentiation|negative regulation of histone methylation|neuron projection development|cardiolipin metabolic process|multicellular organismal response to stress|negative regulation of histone acetylation|social behavior|regulation of gene expression, epigenetic|neuron maturation|negative regulation of neuron apoptotic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|phosphatidylcholine metabolic process|regulation of synaptic plasticity|catecholamine secretion|neuromuscular process controlling posture|neuromuscular process|positive regulation of synapse assembly|regulation of excitatory postsynaptic membrane potential|long-term synaptic potentiation|",four-way junction DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|mRNA binding|protein binding|transcription factor binding|methyl-CpG binding|methyl-CpG binding|double-stranded methylated DNA binding|double-stranded methylated DNA binding|double-stranded methylated DNA binding|enzyme binding|protein domain specific binding|chromatin DNA binding|siRNA binding|poly(A) RNA binding|unmethylated CpG binding|protein N-terminus binding|,10,-0.3,2.85,10,-0.4,1.64,-0.3,4.13,-4.13,0.179,0,0,-1.3,0.4
ENSMUSG00000047371,ZFP768,zinc finger protein 768,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|poly(A) RNA binding|metal ion binding|,10,0.3,2.66,10,0.2,2.01,0.3,4.12,4.12,0.18,0,0,-0.2,1.1
ENSMUSG00000024268,CELF4,"CUGBP, Elav-like family member 4",nucleus|cytoplasm|,"regulation of alternative mRNA splicing, via spliceosome|mRNA splice site selection|mRNA processing|RNA splicing|positive regulation of mRNA splicing, via spliceosome|negative regulation of excitatory postsynaptic membrane potential|",nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|,10,-0.1,0.0123,10,0.5,5.6,0.4,4.12,4.12,0.18,0,0,-0.2,1.4
ENSMUSG00000035355,KCNH4,"potassium voltage-gated channel, subfamily H (eag-related), member 4",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|regulation of ion transmembrane transport|regulation of membrane potential|potassium ion transmembrane transport|,voltage-gated potassium channel activity|,10,0,0,10,-0.4,5.48,-0.3,4.11,-4.11,0.181,0,0,-1.2,0.9
ENSMUSG00000040331,NSMCE4A,non-SMC element 4 homolog A (S. cerevisiae),nucleus|Smc5-Smc6 complex|,positive regulation of response to DNA damage stimulus|,molecular_function|,10,1,2,9,0.4,3.12,0.4,4.05,4.05,0.184,0,0,-1,1.7
ENSMUSG00000025494,SIGIRR,single immunoglobulin and toll-interleukin 1 receptor (TIR) domain,membrane|integral component of membrane|,negative regulation of cytokine-mediated signaling pathway|acute-phase response|signal transduction|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of chemokine biosynthetic process|,None,10,-0.5,2.94,10,-0.2,1.52,-0.3,4.05,-4.05,0.184,0,0,-1.3,0.4
ENSMUSG00000026805,BARHL1,BarH-like 1 (Drosophila),nucleus|,"neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|sensory perception of sound|midbrain development|negative regulation of neuron apoptotic process|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|,10,1.2,6.35,10,0.1,0.507,0.6,4.02,4.02,0.185,0,0,0.1,1.9
ENSMUSG00000041560,GLTSCR2,glioma tumor suppressor candidate region gene 2,nucleolus|intracellular membrane-bounded organelle|,biological_process|,poly(A) RNA binding|,9,-0.1,0.441,9,-1.5,7.12,-1.4,4.01,-4.01,0.186,0,0,-3,-0.1
ENSMUSG00000042446,ZMYM4,"zinc finger, MYM-type 4",nucleus|cytoplasm|,cytoskeleton organization|regulation of cell morphogenesis|,molecular_function|zinc ion binding|metal ion binding|,10,0.6,2.6,10,0.3,1.81,0.4,4,4,0.187,0,0,-0.2,1.4
ENSMUSG00000091736,YY2,Yy2 transcription factor,None,biological_process|,None,10,0.5,1.77,10,1.1,3.72,0.9,3.97,3.97,0.188,0,0,0.1,2
ENSMUSG00000009076,ZMAT5,"zinc finger, matrin type 5",nucleus|spliceosomal complex|U12-type spliceosomal complex|,mRNA processing|biological_process|RNA splicing|,zinc ion binding|metal ion binding|,10,-0.2,0.771,10,-0.3,3.53,-0.3,3.96,-3.96,0.189,0,0,-1.2,0.3
ENSMUSG00000034681,RNPS1,ribonucleic acid binding protein S1,nucleus|cytoplasm|ASAP complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of alternative mRNA splicing, via spliceosome|mRNA processing|RNA splicing|positive regulation of apoptotic process|negative regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|DNA binding|RNA binding|mRNA 3'-UTR binding|poly(A) RNA binding|,10,-0.8,6.25,10,0.7,2.85,0.4,3.92,3.92,0.191,0,0,-1.7,1.2
ENSMUSG00000027806,TSC22D2,"TSC22 domain family, member 2",cellular_component|,response to osmotic stress|,molecular_function|,10,0.2,0.62,10,0.4,3.82,0.4,3.92,3.92,0.191,0,0,-0.4,1.3
ENSMUSG00000042063,ZFP386,zinc finger protein 386 (Kruppel-like),cellular_component|,"regulation of transcription, DNA-templated|negative regulation of transcription during meiosis|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.9,1.87,10,0.7,2.42,0.7,3.92,3.92,0.191,0,0,0,1.8
ENSMUSG00000040621,GEMIN8,gem (nuclear organelle) associated protein 8,nucleus|cytoplasm|cytosol|SMN complex|SMN-Sm protein complex|,spliceosomal snRNP assembly|mRNA processing|RNA splicing|,None,10,-0.9,3.47,10,1.4,1.59,-0.8,3.91,-3.91,0.191,0,0,-2,1.2
ENSMUSG00000035653,LRFN5,leucine rich repeat and fibronectin type III domain containing 5,membrane|integral component of membrane|,None,None,10,0.4,4,10,0.2,0.873,0.3,3.91,3.91,0.191,0,0,-0.6,1.1
ENSMUSG00000002280,NARFL,nuclear prelamin A recognition factor-like,CIA complex|,"response to hypoxia|hematopoietic progenitor cell differentiation|regulation of transcription, DNA-templated|iron-sulfur cluster assembly|iron-sulfur cluster assembly|oxygen homeostasis|","molecular_function|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",10,-0.7,2.81,10,1.1,5.14,0.3,3.83,3.83,0.196,0,0,-0.9,2
ENSMUSG00000049606,ZFP644,zinc finger protein 644,cellular_component|,biological_process|,molecular_function|,10,0.5,5.71,10,-0.6,0.894,0.3,3.83,3.83,0.196,0,0,-0.9,1.5
ENSMUSG00000027981,RNPC3,"RNA-binding region (RNP1, RRM) containing 3",nucleus|nucleus|U12-type spliceosomal complex|,biological_process|,nucleotide binding|molecular_function|nucleic acid binding|RNA binding|,9,0.2,0.491,9,-0.6,5.24,-0.5,3.81,-3.81,0.197,0,0,-1.7,0.9
ENSMUSG00000027752,EXOSC8,exosome component 8,exosome (RNase complex)|nucleus|cytoplasm|,rRNA processing|biological_process|,RNA binding|AU-rich element binding|,8,-0.9,6.56,8,0.5,1.86,-0.9,3.8,-3.8,0.198,0,0,-2,0.5
ENSMUSG00000038622,MED30,mediator complex subunit 30,nucleus|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|stem cell maintenance|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|",RNA polymerase II transcription cofactor activity|transcription cofactor activity|receptor activity|protein binding|thyroid hormone receptor binding|,9,1,3.5,9,-0.7,1.39,0.7,3.79,3.79,0.198,0,0,-1,1.9
ENSMUSG00000045763,BASP1,"brain abundant, membrane attached signal protein 1",nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|COP9 signalosome|membrane|nuclear speck|cell junction|cell projection|extracellular vesicular exosome|,"negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|glomerular visceral epithelial cell differentiation|",transcription corepressor activity|transcription corepressor activity|protein binding|protein domain specific binding|transcription regulatory region DNA binding|,10,-0.3,2.45,10,-0.4,1.64,-0.3,3.78,-3.78,0.199,0,0,-1.4,0.3
ENSMUSG00000033055,ANKRD54,ankyrin repeat domain 54,nucleus|cytoplasm|midbody|,nucleocytoplasmic transport|positive regulation of erythrocyte differentiation|regulation of protein kinase activity|regulation of intracellular signal transduction|,protein binding|protein kinase regulator activity|protein complex binding|,10,0.4,1.48,10,0.3,2.49,0.3,3.73,3.73,0.201,0,0,-0.3,1.2
ENSMUSG00000020743,MIF4GD,MIF4G domain containing,nucleus|nucleolus|cytoplasm|,regulation of translation|,RNA binding|protein C-terminus binding|,9,0.3,2.96,9,-0.8,1.24,0.3,3.71,3.71,0.203,0,0,-1.5,1.2
ENSMUSG00000059975,ZFP74,zinc finger protein 74,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.3,0.499,10,-0.4,3.46,-0.3,3.7,-3.7,0.203,0,0,-1.4,0.5
ENSMUSG00000037791,PHF12,PHD finger protein 12,nucleus|Sin3 complex|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-templated|",RNA polymerase II transcription corepressor activity|transcription corepressor binding|zinc ion binding|phosphatidylinositol binding|metal ion binding|,9,0.9,0.949,9,-0.9,6.29,-0.6,3.63,-3.63,0.208,0,0,-2,0.8
ENSMUSG00000026491,AHCTF1,AT hook containing transcription factor 1,"chromosome, centromeric region|kinetochore|condensed chromosome kinetochore|chromatin|nucleus|nuclear pore|chromosome|cytoplasm|nuclear matrix|nuclear pore outer ring|nuclear membrane|extracellular vesicular exosome|","cytokinesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transport|cell cycle|mitotic nuclear division|multicellular organismal development|protein transport|hemopoiesis|positive regulation of transcription, DNA-templated|mRNA transport|nuclear pore complex assembly|cell division|",DNA binding|sequence-specific DNA binding transcription factor activity|,9,-0.3,2.13,8,1.1,4.76,0.9,3.62,3.62,0.208,0,0,-0.9,2
ENSMUSG00000029427,ZCCHC8,"zinc finger, CCHC domain containing 8",nucleus|spliceosomal complex|catalytic step 2 spliceosome|,mRNA processing|biological_process|RNA splicing|,nucleic acid binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0.1,0.123,10,0.7,4.13,0.4,3.62,3.62,0.208,0,0,-0.1,1.7
ENSMUSG00000048686,HMGB4,high-mobility group box 4,nucleus|chromosome|,None,DNA binding|,10,-0.4,4.25,10,0,0,-0.4,3.59,-3.59,0.21,0,0,-1.4,0.3
ENSMUSG00000012640,ZFP715,zinc finger protein 715,nucleus|cytoplasm|intermediate filament cytoskeleton|,biological_process|,molecular_function|metal ion binding|,10,-0.2,1.54,10,-0.2,2.27,-0.2,3.58,-3.58,0.211,0,0,-1.6,0.5
ENSMUSG00000032340,NEO1,neogenin,plasma membrane|membrane|integral component of membrane|,"regulation of transcription, DNA-templated|cell adhesion|myoblast fusion|iron ion homeostasis|",receptor activity|protein binding|cadherin binding|,10,-1.3,5.99,10,-0.2,0.792,-0.2,3.57,-3.57,0.212,0,0,-2,-0.1
ENSMUSG00000028282,CASP8AP2,caspase 8 associated protein 2,nucleus|cytoplasm|mitochondrion|PML body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|cell cycle|extrinsic apoptotic signaling pathway via death domain receptors|extrinsic apoptotic signaling pathway via death domain receptors|Fas signaling pathway|regulation of RNA biosynthetic process|",protease binding|DNA binding|transcription corepressor activity|protein binding|cysteine-type endopeptidase activator activity involved in apoptotic process|SUMO polymer binding|identical protein binding|,10,0.2,1.24,10,-0.8,4.54,-0.6,3.56,-3.56,0.213,0,0,-1.7,1.2
ENSMUSG00000048385,SCRT1,"scratch homolog 1, zinc finger protein (Drosophila)",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of neuron migration|",nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,0.3,1.98,10,0.9,2.34,0.3,3.55,3.55,0.213,0,0,-0.1,1.7
ENSMUSG00000032119,HINFP,histone H4 transcription factor,nucleus|nucleoplasm|Cajal body|,"DNA damage checkpoint|G1/S transition of mitotic cell cycle|regulation of transcription involved in G1/S transition of mitotic cell cycle|in utero embryonic development|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of gene expression|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|establishment of protein localization|myoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|enzyme binding|histone binding|transcription regulatory region DNA binding|metal ion binding|,9,-0.5,3.41,8,0.3,1.9,-0.5,3.55,-3.55,0.213,0,0,-1.3,1.7
ENSMUSG00000001517,FOXM1,forkhead box M1,intracellular|nucleus|nucleus|cytoplasm|,"G2/M transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|vasculogenesis|liver development|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cell cycle|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of stress-activated MAPK cascade|regulation of cell proliferation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of Ras protein signal transduction|regulation of cell cycle arrest|negative regulation of cell aging|regulation of reactive oxygen species metabolic process|positive regulation of double-strand break repair|positive regulation of double-strand break repair|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein kinase binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.4,2.78,10,0.2,0.986,0.4,3.5,3.5,0.217,0,0,-0.2,1.4
ENSMUSG00000001542,ELL2,elongation factor RNA polymerase II 2,nucleus|cytoplasm|centrosome|transcription elongation factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription elongation from RNA polymerase II promoter|positive regulation of transcription elongation from RNA polymerase II promoter|",None,10,0.3,2.65,10,0.2,1.2,0.3,3.48,3.48,0.218,0,0,-0.3,1.3
ENSMUSG00000037855,ZFP365,zinc finger protein 365,cytoplasm|cytoskeleton|,None,None,10,-0.3,3.07,10,-0.2,1.09,-0.2,3.46,-3.46,0.219,0,0,-1.2,0.7
ENSMUSG00000096334,SH2D1B1,SH2 domain containing 1B1,intracellular|,leukocyte activation involved in immune response|positive regulation of natural killer cell mediated immunity|natural killer cell inhibitory signaling pathway|positive regulation of signal transduction|peptidyl-tyrosine phosphorylation|negative regulation of interferon-gamma production|positive regulation of innate immune response|negative regulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of peptidyl-tyrosine phosphorylation|,phosphotyrosine binding|protein binding|signaling adaptor activity|,8,-1.3,5.71,8,-0.2,0.653,-1.2,3.45,-3.45,0.219,0,0,-2,0
ENSMUSG00000063488,ZKSCAN7,zinc finger with KRAB and SCAN domains 7,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|metal ion binding|,10,-1.2,5.3,10,0.1,0.299,-1.2,3.42,-3.42,0.221,0,0,-2,0
ENSMUSG00000031706,RFX1,"regulatory factor X, 1 (influences HLA class II expression)",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|,10,-0.1,0.454,10,-0.5,4.04,-0.3,3.39,-3.39,0.224,0,0,-1.6,0.3
ENSMUSG00000013822,ELOF1,"elongation factor 1 homolog (ELF1, S. cerevisiae)",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|translation|translational elongation|biological_process|",molecular_function|translation elongation factor activity|metal ion binding|,8,-0.4,0.891,10,0.5,4.19,0.4,3.39,3.39,0.224,0,0,-0.8,1.5
ENSMUSG00000024891,SLC29A2,"solute carrier family 29 (nucleoside transporters), member 2",nucleus|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,transport|nucleoside transport|nucleoside transport|nucleoside transmembrane transport|,nucleoside transmembrane transporter activity|,10,0.3,0.689,10,0.6,3.43,0.6,3.38,3.38,0.225,0,0,-0.1,1.6
ENSMUSG00000039834,ZFP335,zinc finger protein 335,nucleus|histone methyltransferase complex|histone methyltransferase complex|,"in utero embryonic development|positive regulation of neuroblast proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|brain development|brain development|regulation of gene expression|cerebral cortex neuron differentiation|cerebral cortex neuron differentiation|regulation of gene expression, epigenetic|neuron projection morphogenesis|brain morphogenesis|brain morphogenesis|positive regulation of lymphocyte proliferation|regulation of neurogenesis|positive regulation of neurogenesis|regulation of histone H3-K4 methylation|histone H3-K4 trimethylation|",RNA polymerase II core promoter sequence-specific DNA binding|nucleic acid binding|DNA binding|protein binding|transcription regulatory region DNA binding|metal ion binding|,10,-0.7,4.18,10,0.7,3.72,0.8,3.38,3.38,0.225,0,0,-1.1,1.9
ENSMUSG00000023902,ZSCAN10,zinc finger and SCAN domain containing 10,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|stem cell differentiation|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|metal ion binding|,10,0.4,2.87,10,0.2,1.03,0.4,3.38,3.38,0.225,0,0,-0.4,1.5
ENSMUSG00000075588,HOXB2,homeobox B2,nucleus|,"morphogenesis of an epithelial sheet|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|dorsal/ventral pattern formation|rhombomere 3 development|rhombomere 4 development|facial nerve structural organization|embryonic skeletal system morphogenesis|skeletal system morphogenesis|skeletal system morphogenesis|neural nucleus development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.7,3.81,10,-0.3,1.03,-0.5,3.37,-3.37,0.225,0,0,-1.6,0.2
ENSMUSG00000091405,HIST2H4,"histone cluster 2, H4",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,protein binding|poly(A) RNA binding|,10,-0.2,1.07,10,-1.3,4.42,-1.3,3.36,-3.36,0.226,0,0,-2,-0.1
ENSMUSG00000035047,KRI1,KRI1 homolog (S. cerevisiae),nucleolus|,biological_process|,poly(A) RNA binding|,10,0.8,3.35,10,-0.3,1.54,-0.3,3.36,-3.36,0.226,0,0,-1.7,1.3
ENSMUSG00000071341,EGR4,early growth response 4,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|cellular response to cAMP|cellular response to gonadotropin stimulus|",RNA polymerase II regulatory region sequence-specific DNA binding|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.4,5.58,-0.3,3.34,-3.34,0.227,0,0,-1.4,0.4
ENSMUSG00000005621,ZFP592,zinc finger protein 592,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|protein binding|metal ion binding|,10,0,0,10,-0.4,5.47,-0.3,3.34,-3.34,0.227,0,0,-1.4,0.3
ENSMUSG00000031660,BRD7,bromodomain containing 7,nucleus|nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|cell cycle|negative regulation of cell proliferation|Wnt signaling pathway|positive regulation of histone acetylation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of G1/S transition of mitotic cell cycle|regulation of RNA biosynthetic process|",p53 binding|transcription coactivator activity|transcription corepressor activity|transcription corepressor activity|protein binding|transcription factor binding|histone binding|transcription regulatory region DNA binding|lysine-acetylated histone binding|,10,-0.2,1.31,10,-0.3,2.36,-0.3,3.33,-3.33,0.228,0,0,-1.2,1.1
ENSMUSG00000070697,UTP3,"UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)",nucleus|nucleolus|,multicellular organismal development|brain development|chromatin modification|,protein binding|poly(A) RNA binding|,10,-0.7,3.8,10,0.4,4.87,0.4,3.31,3.31,0.229,0,0,-1.3,1.7
ENSMUSG00000048485,ZBTB8B,zinc finger and BTB domain containing 8b,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.6,3.24,10,0.3,1.56,0.4,3.29,3.29,0.231,0,0,-0.7,1.6
ENSMUSG00000072980,OIP5,Opa interacting protein 5,"chromosome, centromeric region|chromatin|nucleus|nucleus|chromosome|cytoplasm|chromocenter|Cajal body|",cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,7,0.4,3.21,6,0.7,0.635,0.5,3.29,3.29,0.231,0,0,-0.3,1.8
ENSMUSG00000047264,ZFP358,zinc finger protein 358,cellular_component|,biological_process|,molecular_function|,10,-0.4,2.31,10,-0.2,1.46,-0.3,3.28,-3.28,0.232,0,0,-1.4,0.3
ENSMUSG00000024986,HHEX,hematopoietically expressed homeobox,nucleus|nucleus|cytoplasm|cytoplasm|protein-DNA complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|vasculogenesis|in utero embryonic development|liver development|morphogenesis of an epithelium|myeloid leukocyte differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|mRNA export from nucleus|signal transduction|multicellular organismal development|endoderm development|cell proliferation|organ morphogenesis|anterior/posterior pattern specification|Wnt signaling pathway|negative regulation of angiogenesis|negative regulation of angiogenesis|poly(A)+ mRNA export from nucleus|interkinetic nuclear migration|hemopoiesis|cell differentiation|positive regulation of Wnt signaling pathway|B cell differentiation|thyroid gland development|forebrain development|negative regulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of vascular endothelial growth factor receptor signaling pathway|pancreas development|protein localization to nucleus|embryonic heart tube development|multicellular organism growth|regulation of cell proliferation|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|embryonic organ development|tissue morphogenesis|forebrain morphogenesis|primary lung bud formation|common bile duct development|gall bladder development|hepatic duct development|hepatoblast differentiation|hepatocyte differentiation|DNA conformation change|primitive streak formation|primitive streak formation|","DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|eukaryotic initiation factor 4E binding|DNA binding, bending|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|repressing transcription factor binding|HMG box domain binding|",10,0.2,0.899,10,0.4,2.97,0.3,3.27,3.27,0.233,0,0,-0.3,1.3
ENSMUSG00000025899,ALKBH8,"alkB, alkylation repair homolog 8 (E. coli)",nucleus|cytoplasm|cytosol|,cellular response to DNA damage stimulus|metabolic process|tRNA methylation|methylation|oxidation-reduction process|,"nucleotide binding|rRNA (adenine-N6,N6-)-dimethyltransferase activity|sulfonate dioxygenase activity|nucleic acid binding|RNA binding|catalytic activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|procollagen-proline dioxygenase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|hypophosphite dioxygenase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|DNA-N1-methyladenine dioxygenase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.8,2.82,10,-0.2,1.31,-0.4,3.27,-3.27,0.233,0,0,-1.8,0.8
ENSMUSG00000057093,C030039L03RIK,RIKEN cDNA C030039L03 gene,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.5,3.76,10,-0.1,0.13,-0.4,3.27,-3.27,0.233,0,0,-1.5,0.6
ENSMUSG00000046364,RPL27A,ribosomal protein L27A,membrane|cytosolic large ribosomal subunit|cytosolic ribosome|,translation|,structural constituent of ribosome|poly(A) RNA binding|,10,0.3,2.39,10,0.3,1.08,0.3,3.26,3.26,0.233,0,0,-1.5,1.2
ENSMUSG00000043059,ZFP513,zinc finger protein 513,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|retina development in camera-type eye|",nucleic acid binding|DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,-0.4,3.75,-0.3,3.24,-3.24,0.235,0,0,-1.3,0.6
ENSMUSG00000078427,SARNP,SAP domain containing ribonucleoprotein,transcription export complex|nucleus|nucleus|nuclear speck|intracellular membrane-bounded organelle|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|mRNA export from nucleus|,RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|protein binding|protein C-terminus binding|poly(A) RNA binding|RS domain binding|,6,-0.5,1.98,6,-0.3,2.02,-0.4,3.23,-3.23,0.236,0,0,-1.7,1.1
ENSMUSG00000035125,GCFC2,GC-rich sequence DNA binding factor 2,nucleus|nucleolus|U2-type post-mRNA release spliceosomal complex|,"negative regulation of transcription from RNA polymerase II promoter|spliceosomal complex assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|mRNA processing|RNA splicing|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.3,0.801,10,0.7,4.56,0.6,3.22,3.22,0.237,0,0,-0.4,1.8
ENSMUSG00000028487,BNC2,basonuclin 2,nucleus|nucleus|cytoplasm|plasma membrane|,"endochondral bone growth|transcription, DNA-templated|regulation of transcription, DNA-templated|tongue development|palate development|mesenchyme development|",DNA binding|metal ion binding|,10,0.2,0.414,10,-1,5.56,-0.9,3.21,-3.21,0.237,0,0,-2,0.2
ENSMUSG00000079560,HOXA3,homeobox A3,nucleus|,"blood vessel remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of cell proliferation|organ morphogenesis|anterior/posterior pattern specification|specification of organ position|glossopharyngeal nerve morphogenesis|glossopharyngeal nerve morphogenesis|thyroid gland development|thyroid gland development|thymus development|thymus development|organ formation|embryonic skeletal system morphogenesis|embryonic skeletal system development|cartilage development|parathyroid gland development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|HMG box domain binding|,10,-0.4,3.18,10,-0.2,0.605,-0.3,3.2,-3.2,0.238,0,0,-1.3,0.5
ENSMUSG00000057551,ZFP317,zinc finger protein 317,nucleus|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.957,10,-0.3,2.94,-0.3,3.19,-3.19,0.239,0,0,-1.2,0.8
ENSMUSG00000014771,PDCD2,programmed cell death 2,nucleus|cytoplasm|extracellular vesicular exosome|,apoptotic process|,DNA binding|enzyme binding|metal ion binding|,7,0.8,1.93,8,0.3,1.66,0.3,3.19,3.19,0.239,0,0,-0.7,1.8
ENSMUSG00000039737,PRKRIP1,Prkr interacting protein 1 (IL11 inducible),nucleus|nucleolus|extracellular vesicular exosome|,renal system process|negative regulation of protein kinase activity|negative regulation of phosphorylation|,double-stranded RNA binding|protein kinase inhibitor activity|protein binding|protein kinase binding|,10,-0.5,4.84,9,0,0,-0.4,3.18,-3.18,0.24,0,0,-1.5,0.6
ENSMUSG00000035168,TANC1,"tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1",plasma membrane|membrane|cell junction|dendrite|neuronal cell body|axon terminus|synapse|postsynaptic membrane|,myoblast fusion|visual learning|dendritic spine maintenance|,molecular_function|,9,0.4,2.56,9,-0.9,3.29,0.4,3.17,3.17,0.241,0,0,-1.8,1
ENSMUSG00000029028,LRRC47,leucine rich repeat containing 47,cellular_component|,biological_process|,RNA binding|phenylalanine-tRNA ligase activity|poly(A) RNA binding|,10,-0.3,1.87,10,-0.4,1.56,-0.4,3.16,-3.16,0.242,0,0,-1.4,0.4
ENSMUSG00000045365,RBM15B,RNA binding motif protein 15B,nucleus|nucleoplasm|,"regulation of alternative mRNA splicing, via spliceosome|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-1.2,5.1,10,-0.2,0.258,-0.2,3.12,-3.12,0.245,0,0,-2,0.1
ENSMUSG00000018923,MED11,mediator complex subunit 11,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|biological_process|",RNA polymerase II transcription cofactor activity|molecular_function|,8,1.4,5.85,9,-0.9,2.88,-0.7,3.12,-3.12,0.245,0,0,-1.6,1.9
ENSMUSG00000038000,ACD,adrenocortical dysplasia,"chromosome, telomeric region|nuclear telomere cap complex|nuclear telomere cap complex|nucleus|chromosome|","telomere maintenance|skeletal system development|urogenital system development|intracellular protein transport|telomere capping|telomere capping|embryonic limb morphogenesis|protection from non-homologous end joining at telomere|telomere assembly|negative regulation of telomere maintenance via telomerase|segmentation|positive regulation of telomerase activity|positive regulation of single-stranded telomeric DNA binding|protein localization to chromosome, telomeric region|",DNA binding|protein binding|DNA polymerase binding|,10,0.6,2.15,9,-0.6,5.14,-0.4,3.11,-3.11,0.246,0,0,-1.5,1.1
ENSMUSG00000024081,CEBPZ,CCAAT/enhancer binding protein zeta,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|poly(A) RNA binding|,10,0.8,2.97,10,-0.4,2.26,-0.4,3.04,-3.04,0.251,0,0,-1.3,1.5
ENSMUSG00000003970,RPL8,ribosomal protein L8,intracellular|cytoplasm|ribosome|large ribosomal subunit|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,RNA binding|structural constituent of ribosome|rRNA binding|poly(A) RNA binding|,3,1.2,4.99,4,0,0,1.2,3.04,3.04,0.251,0,0,-0.4,2
ENSMUSG00000037579,KCNH3,"potassium voltage-gated channel, subfamily H (eag-related), member 3",integral component of plasma membrane|membrane|integral component of membrane|,phosphorelay signal transduction system|transport|ion transport|potassium ion transport|signal transduction|regulation of ion transmembrane transport|regulation of membrane potential|transmembrane transport|potassium ion transmembrane transport|,phosphorelay sensor kinase activity|signal transducer activity|ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|,10,1.1,6.09,10,0,0,0.9,3.03,3.03,0.252,0,0,0,1.9
ENSMUSG00000024274,ZSCAN30,zinc finger and SCAN domain containing 30,None,biological_process|,molecular_function|,10,-0.3,3.18,9,0.1,0.157,-0.3,3.01,-3.01,0.254,0,0,-1.2,1.2
ENSMUSG00000040302,RBM48,RNA binding motif protein 48,nucleus|,biological_process|,molecular_function|RNA binding|,8,-0.4,4.3,9,0.6,2.3,-0.4,2.99,-2.99,0.255,0,0,-1.3,1.5
ENSMUSG00000058248,KCNH1,"potassium voltage-gated channel, subfamily H (eag-related), member 1",nucleus|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,phosphorelay signal transduction system|transport|ion transport|potassium ion transport|signal transduction|regulation of ion transmembrane transport|regulation of membrane potential|transmembrane transport|potassium ion transmembrane transport|,phosphorelay sensor kinase activity|signal transducer activity|ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|calmodulin binding|,10,0.6,2.88,10,0.9,0.642,0.8,2.97,2.97,0.257,0,0,-0.3,1.8
ENSMUSG00000027405,NOP56,NOP56 ribonucleoprotein,nucleus|nucleolus|small nucleolar ribonucleoprotein complex|cytoplasm|membrane|ribonucleoprotein complex|pre-snoRNP complex|,biological_process|ribosome biogenesis|,snoRNA binding|poly(A) RNA binding|,8,-0.8,5.17,7,1.2,4.51,-0.8,2.95,-2.95,0.259,0,0,-1.7,1.8
ENSMUSG00000022237,ANKRD33B,ankyrin repeat domain 33B,cellular_component|,biological_process|,molecular_function|DNA binding|,10,-0.2,2.85,10,-0.1,0.322,-0.2,2.94,-2.94,0.259,0,0,-1.3,0.7
ENSMUSG00000017478,ZC3H18,zinc finger CCCH-type containing 18,nucleus|,biological_process|,poly(A) RNA binding|metal ion binding|,9,0.4,1.66,9,0.3,1.64,0.3,2.94,2.94,0.259,0,0,-1,1.5
ENSMUSG00000037570,MCRS1,microspherule protein 1,histone acetyltransferase complex|nucleus|Ino80 complex|MLL1 complex|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|chromatin modification|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|",histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|histone acetyltransferase activity (H4-K16 specific)|,10,-0.3,1.88,10,0.4,1.84,-0.3,2.92,-2.92,0.261,0,0,-1.4,1.1
ENSMUSG00000064141,ZFP69,zinc finger protein 69,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.2,0.656,10,-0.5,2.82,-0.5,2.92,-2.92,0.261,0,0,-1.6,0.3
ENSMUSG00000003234,ABCF3,"ATP-binding cassette, sub-family F (GCN20), member 3",membrane|,biological_process|defense response to virus|,nucleotide binding|protein binding|ATP binding|ATPase activity|,10,-0.2,0.45,10,-0.3,2.8,-0.3,2.91,-2.91,0.262,0,0,-1.3,0.4
ENSMUSG00000028610,DMRTB1,"DMRT-like family B with proline-rich C-terminal, 1",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,-0.4,4.09,10,-0.1,0.466,-0.3,2.88,-2.88,0.265,0,0,-1.4,0.3
ENSMUSG00000033039,MICALL1,"microtubule associated monooxygenase, calponin and LIM domain containing -like 1",endosome|late endosome|endosome membrane|membrane|extrinsic component of membrane|,"protein targeting to membrane|transport|endocytosis|receptor-mediated endocytosis|protein transport|neuron projection development|neuron projection development|endocytic recycling|slow endocytic recycling|protein localization to endosome|membrane tubulation|cellular response to nerve growth factor stimulus|retrograde transport, endosome to plasma membrane|",protein binding|zinc ion binding|Rab GTPase binding|Rab GTPase binding|identical protein binding|metal ion binding|phosphatidic acid binding|,10,0.3,3.34,10,0.1,0.394,0.2,2.87,2.87,0.266,0,0,-0.5,1.3
ENSMUSG00000071369,MAP3K5,mitogen-activated protein kinase kinase kinase 5,intracellular|cytoplasm|endoplasmic reticulum|protein kinase complex|,MAPK cascade|MAPK cascade|activation of MAPKK activity|activation of MAPKK activity|activation of MAPK activity|positive regulation of protein phosphorylation|immune system process|protein phosphorylation|protein phosphorylation|apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|response to stress|JNK cascade|intrinsic apoptotic signaling pathway in response to oxidative stress|intrinsic apoptotic signaling pathway in response to oxidative stress|regulation of cell death|phosphorylation|positive regulation of apoptotic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|innate immune response|cellular response to hydrogen peroxide|programmed necrotic cell death|positive regulation of neuron death|cellular response to reactive nitrogen species|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|cysteine-type endopeptidase activator activity involved in apoptotic process|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein phosphatase binding|protein homodimerization activity|metal ion binding|",10,-0.3,2.08,10,-0.2,1.07,-0.2,2.83,-2.83,0.269,0,0,-1.3,0.7
ENSMUSG00000021997,LRRC63,leucine rich repeat containing 63,cellular_component|,biological_process|,molecular_function|,10,0.4,1.92,10,-0.3,2.34,0.4,2.82,2.82,0.27,0,0,-0.8,1.8
ENSMUSG00000022332,KHDRBS3,"KH domain containing, RNA binding, signal transduction associated 3",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|positive regulation of RNA splicing|",RNA binding|single-stranded RNA binding|SH3 domain binding|poly(A) RNA binding|,10,0.3,2.57,10,0.1,0.614,0.2,2.8,2.8,0.272,0,0,-0.4,1.6
ENSMUSG00000029686,CUL1,cullin 1,SCF ubiquitin ligase complex|SCF ubiquitin ligase complex|cullin-RING ubiquitin ligase complex|,ubiquitin-dependent protein catabolic process|protein monoubiquitination|apoptotic process|cell proliferation|organ morphogenesis|viral process|protein ubiquitination|protein ubiquitination|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|,ubiquitin-protein transferase activity|protein binding|ubiquitin protein ligase binding|,10,0.4,4.02,10,-0.1,0.143,0.3,2.8,2.8,0.272,0,0,-0.4,1.5
ENSMUSG00000004054,MAP3K11,mitogen-activated protein kinase kinase kinase 11,cytoplasm|centrosome|cytoskeleton|microtubule|membrane|,mitotic G1 phase|activation of MAPK activity|protein phosphorylation|microtubule-based process|JNK cascade|activation of JNKK activity|activation of JUN kinase activity|cell death|cell proliferation|phosphorylation|positive regulation of apoptotic process|positive regulation of JUN kinase activity|positive regulation of neuron apoptotic process|positive regulation of JNK cascade|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase binding|mitogen-activated protein kinase kinase kinase binding|identical protein binding|protein homodimerization activity|Rac GTPase binding|",10,0.3,0.197,10,-1,5.86,-1,2.77,-2.77,0.275,0,0,-2,0.1
ENSMUSG00000008301,PHAX,phosphorylated adaptor for RNA export,nucleus|nucleus|nucleolus|cytoplasm|neuronal cell body|intracellular membrane-bounded organelle|,snRNA export from nucleus|transport|protein transport|,RNA binding|toxic substance binding|,9,-0.1,0.405,10,0.7,4.76,0.7,2.77,2.77,0.275,0,0,-0.4,1.9
ENSMUSG00000043290,ZFP784,zinc finger protein 784,nucleus|,"hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.3,3.73,10,0,0,-0.3,2.76,-2.76,0.276,0,0,-1.4,0.6
ENSMUSG00000049321,ZFP2,zinc finger protein 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.7,5.55,10,0,0,0.5,2.75,2.75,0.277,0,0,-0.1,2
ENSMUSG00000041781,CPSF2,cleavage and polyadenylation specific factor 2,nucleus|mRNA cleavage and polyadenylation specificity factor complex|mRNA cleavage and polyadenylation specificity factor complex|membrane|,mRNA polyadenylation|mRNA cleavage|mRNA processing|histone mRNA 3'-end processing|,molecular_function|RNA binding|,7,0.8,2.43,6,0.3,1.55,0.5,2.75,2.75,0.277,0,0,-1.8,1.6
ENSMUSG00000028688,TOE1,"target of EGR1, member 1 (nuclear)",nucleus|,biological_process|,nucleic acid binding|metal ion binding|,7,0.4,3.12,8,-0.3,1.63,0.4,2.74,2.74,0.278,0,0,-0.8,1.9
ENSMUSG00000030315,VGLL4,vestigial like 4 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,10,0.4,4.47,10,0,0,0.3,2.72,2.72,0.28,0,0,-0.7,1.9
ENSMUSG00000050064,ZFP697,zinc finger protein 697,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.5,0.975,10,0.3,2.07,0.2,2.68,2.68,0.283,0,0,-0.6,1.6
ENSMUSG00000028609,MAGOH,"mago-nashi homolog, proliferation-associated (Drosophila)",nucleus|spliceosomal complex|cytoplasm|exon-exon junction complex|catalytic step 2 spliceosome|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of alternative mRNA splicing, via spliceosome|mRNA processing|regulation of translation|transport|female gamete generation|RNA splicing|mRNA transport|",RNA binding|poly(A) RNA binding|,5,-0.3,2.7,6,0.6,3.46,-0.3,2.68,-2.68,0.283,0,0,-1.4,1.7
ENSMUSG00000033970,RFC3,replication factor C (activator 1) 3,nucleus|DNA replication factor C complex|,ATP catabolic process|DNA replication|,nucleotide binding|DNA binding|ATP binding|ATPase activity|,6,-0.9,4.47,5,0.8,3.34,-0.9,2.68,-2.68,0.283,0,0,-2,1.4
ENSMUSG00000022974,PAXBP1,PAX3 and PAX7 binding protein 1,nucleus|cytosol|,"transcription, DNA-templated|regulation of transcription, DNA-templated|muscle organ development|regulation of satellite cell proliferation|positive regulation of histone methylation|positive regulation of histone methylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of myoblast proliferation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|,10,0.2,1.34,10,0.7,3.43,0.2,2.67,2.67,0.284,0,0,-0.9,1.7
ENSMUSG00000020653,KLF11,Kruppel-like factor 11,nucleus|,"regulation of transcription involved in G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|apoptotic process|negative regulation of cell proliferation|positive regulation of apoptotic process|negative regulation of transcription, DNA-templated|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|metal ion binding|,10,0.7,5.69,10,0,0,0.7,2.67,2.67,0.284,0,0,-0.1,1.8
ENSMUSG00000015165,HNRNPL,heterogeneous nuclear ribonucleoprotein L,nucleus|cytoplasm|membrane|ribonucleoprotein complex|pronucleus|extracellular vesicular exosome|,mRNA processing|,nucleotide binding|nucleic acid binding|RNA binding|transcription regulatory region DNA binding|poly(A) RNA binding|,8,-1,4.06,9,0.6,1.85,-0.4,2.66,-2.66,0.285,0,0,-2,0.9
ENSMUSG00000021510,A530054K11RIK,RIKEN cDNA A530054K11 gene,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.2,0.683,10,-0.5,4.66,-0.4,2.65,-2.65,0.286,0,0,-1.5,0.6
ENSMUSG00000066880,ZFP617,zinc finger protein 617,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.4,3.44,10,0.1,0.236,0.3,2.64,2.64,0.287,0,0,-0.2,1.8
ENSMUSG00000032386,TRIP4,thyroid hormone receptor interactor 4,nucleus|cytoplasm|cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",zinc ion binding|ligand-dependent nuclear receptor binding|metal ion binding|,10,-0.7,1.12,10,-0.2,2.27,-0.2,2.63,-2.63,0.288,0,0,-1.7,0.7
ENSMUSG00000033597,CASKIN1,CASK interacting protein 1,cytoplasm|,signal transduction|,protein domain specific binding|,10,0.4,1.52,10,0.2,1.51,0.3,2.63,2.63,0.288,0,0,-0.4,1.5
ENSMUSG00000001383,ZMAT2,"zinc finger, matrin type 2",cellular_component|nucleus|,biological_process|,nucleic acid binding|DNA binding|zinc ion binding|metal ion binding|,10,-0.9,1.7,10,0.9,5.23,0.8,2.6,2.6,0.291,0,0,-1.1,2
ENSMUSG00000091625,LSM5,"LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)",nucleus|spliceosomal complex|cytoplasm|ribonucleoprotein complex|,mRNA processing|mRNA catabolic process|RNA splicing|,RNA binding|protein binding|protein heterodimerization activity|,7,0.4,1.24,7,-0.8,3.95,-0.5,2.58,-2.58,0.293,0,0,-2,0.8
ENSMUSG00000040043,RBMS2,"RNA binding motif, single stranded interacting protein 2",nucleus|,None,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,9,0.3,0.276,9,0.4,2.54,0.3,2.58,2.58,0.293,0,0,-0.5,1.6
ENSMUSG00000046311,ZFP62,zinc finger protein 62,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|metal ion binding|,10,-0.2,1.27,10,-0.3,1.54,-0.2,2.57,-2.57,0.294,0,0,-1.5,0.5
ENSMUSG00000056300,GM13247,predicted gene 13247,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.08,10,0.6,4.89,0.5,2.56,2.56,0.295,0,0,-0.3,1.7
ENSMUSG00000002885,CD97,CD97 antigen,plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcium ion binding|,10,-0.3,3.72,10,0,0,-0.3,2.56,-2.56,0.295,0,0,-1.4,1
ENSMUSG00000011158,BRF1,"BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)",cellular_component|nucleus|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|translation|translational initiation|regulation of mRNA stability|",molecular_function|translation initiation factor activity|zinc ion binding|TBP-class protein binding|metal ion binding|,6,-0.3,3.29,6,-1.3,3.69,-1.3,2.56,-2.56,0.295,0,0,-2,0
ENSMUSG00000067194,EIF1AX,"eukaryotic translation initiation factor 1A, X-linked",cellular_component|,translation|translational initiation|,RNA binding|translation initiation factor activity|,10,-0.4,3.18,10,-0.2,0.313,-0.3,2.56,-2.56,0.295,0,0,-1.5,0.5
ENSMUSG00000029754,DLX6,distal-less homeobox 6,nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|embryonic limb morphogenesis|epithelial cell differentiation|inner ear morphogenesis|anatomical structure formation involved in morphogenesis|positive regulation of epithelial cell proliferation|palate development|head development|",DNA binding|sequence-specific DNA binding|,10,0.1,0.519,10,-0.4,3.75,-0.3,2.55,-2.55,0.295,0,0,-1.4,0.7
ENSMUSG00000055835,ZFP1,zinc finger protein 1,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.3,3.83,-0.3,2.55,-2.55,0.295,0,0,-1.6,0.6
ENSMUSG00000043467,ZBTB37,zinc finger and BTB domain containing 37,cellular_component|nucleus|,biological_process|,molecular_function|metal ion binding|,10,0.4,2.98,10,0.1,0.206,0.2,2.54,2.54,0.297,0,0,-0.6,1.4
ENSMUSG00000029538,SRSF9,serine/arginine-rich splicing factor 9,nucleus|,"mRNA processing|RNA splicing|negative regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.4,2.12,10,0.2,0.868,0.4,2.54,2.54,0.297,0,0,-0.3,1.5
ENSMUSG00000041992,RAPGEF5,Rap guanine nucleotide exchange factor (GEF) 5,intracellular|nucleus|,small GTPase mediated signal transduction|positive regulation of Rap GTPase activity|intracellular signal transduction|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|Rap guanyl-nucleotide exchange factor activity|GTP-dependent protein binding|,10,0.3,2.05,10,-0.3,2.77,-0.2,2.53,-2.53,0.298,0,0,-1.4,1
ENSMUSG00000021540,SMAD5,SMAD family member 5,intracellular|nucleus|transcription factor complex|cytoplasm|protein complex|,"angiogenesis|Mullerian duct regression|osteoblast fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|transforming growth factor beta receptor signaling pathway|multicellular organismal development|germ cell development|cell differentiation|erythrocyte differentiation|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|positive regulation of osteoblast differentiation|positive regulation of transcription from RNA polymerase II promoter|cartilage development|cardiac muscle contraction|bone development|cellular response to organic cyclic compound|cellular response to BMP stimulus|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|ubiquitin protein ligase binding|metal ion binding|,10,0,0,10,0.5,3.93,0.3,2.53,2.53,0.298,0,0,-0.5,1.5
ENSMUSG00000051965,NANOS2,nanos homolog 2 (Drosophila),cytoplasmic mRNA processing body|nucleus|cytoplasm|cytoplasm|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,mRNA catabolic process|regulation of translation|multicellular organismal development|spermatogenesis|cell differentiation|germ-line stem cell maintenance|negative regulation of meiosis|,RNA binding|mRNA binding|protein binding|zinc ion binding|metal ion binding|,10,0.5,3.46,10,0.1,0.594,0.4,2.5,2.5,0.301,0,0,-0.7,1.6
ENSMUSG00000070866,ZFP804A,zinc finger protein 804A,None,biological_process|,metal ion binding|,9,-0.1,0.189,9,-0.3,2.93,-0.2,2.45,-2.45,0.307,0,0,-1.5,0.6
ENSMUSG00000048481,MYPOP,"Myb-related transcription factor, partner of profilin",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|,6,-0.2,1.33,6,-0.3,1.49,-0.2,2.45,-2.45,0.307,0,0,-1.9,0.8
ENSMUSG00000045639,ZFP629,zinc finger protein 629,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,2.02,10,-0.2,0.582,-0.2,2.43,-2.43,0.309,0,0,-1.4,0.8
ENSMUSG00000027514,ZBP1,Z-DNA binding protein 1,nucleus|cytoplasm|cytosol|,immune system process|viral process|innate immune response|defense response to virus|positive regulation of type I interferon-mediated signaling pathway|,DNA binding|DNA binding|left-handed Z-DNA binding|RNA binding|double-stranded RNA adenosine deaminase activity|protein binding|,10,0.7,5.09,10,0,0,0.5,2.41,2.41,0.311,0,0,-0.4,1.7
ENSMUSG00000072949,ACOT1,acyl-CoA thioesterase 1,cytoplasm|mitochondrion|cytosol|,long-chain fatty acid metabolic process|acyl-CoA metabolic process|,palmitoyl-CoA hydrolase activity|hydrolase activity|thiolester hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|acyl-CoA hydrolase activity|,10,0.3,1.21,10,0.5,1.67,0.3,2.39,2.39,0.314,0,0,-0.5,1.6
ENSMUSG00000031665,SALL1,sal-like 1 (Drosophila),heterochromatin|heterochromatin|nucleus|nucleus|nucleus|cytoplasm|chromocenter|NuRD complex|NuRD complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|ureteric bud development|branching involved in ureteric bud morphogenesis|kidney development|neural tube closure|ventricular septum development|ventricular septum development|mesenchymal to epithelial transition involved in metanephros morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|heart development|olfactory nerve development|olfactory bulb development|olfactory bulb interneuron differentiation|neural tube development|positive regulation of Wnt signaling pathway|inductive cell-cell signaling|forelimb morphogenesis|hindlimb morphogenesis|outer ear morphogenesis|embryonic digit morphogenesis|embryonic digit morphogenesis|positive regulation of neuron differentiation|negative regulation of smoothened signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic digestive tract development|limb development|olfactory bulb mitral cell layer development|kidney epithelium development|ureteric bud invasion|regulation of neural precursor cell proliferation|negative regulation of mesoderm development|negative regulation of ectoderm development|",RNA polymerase II transcription factor binding|RNA polymerase II transcription coactivator activity|enhancer sequence-specific DNA binding|nucleic acid binding|DNA binding|chromatin binding|histone deacetylase activity|protein binding|beta-catenin binding|metal ion binding|,10,-0.3,2.39,10,-0.7,0.373,-0.3,2.38,-2.38,0.315,0,0,-1.6,0.7
ENSMUSG00000008193,SPIB,Spi-B transcription factor (Spi-1/PU.1 related),nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|macrophage differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.4,3.83,10,0,0,0.3,2.35,2.35,0.318,0,0,-0.3,1.9
ENSMUSG00000022109,MED4,mediator complex subunit 4,nucleus|membrane|mediator complex|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|",RNA polymerase II transcription cofactor activity|transcription cofactor activity|receptor activity|protein binding|thyroid hormone receptor binding|,10,-0.4,2.69,10,0.2,0.827,-0.4,2.35,-2.35,0.318,0,0,-1.6,0.8
ENSMUSG00000026735,PTF1A,"pancreas specific transcription factor, 1a",intracellular|nucleus|nucleus|transcription factor complex|transcription factor complex|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|embryo development|tissue development|retina layer formation|cerebellum development|cerebellum development|cell differentiation|hindbrain development|pancreas development|pancreas development|exocrine pancreas development|amacrine cell differentiation|cell fate commitment|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|retinoic acid receptor signaling pathway|neuron fate commitment|generation of neurons|generation of neurons|retina morphogenesis in camera-type eye|regulation of neural retina development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|protein binding|sequence-specific DNA binding|protein dimerization activity|E-box binding|,10,-0.4,0.564,10,-0.3,2.11,-0.3,2.35,-2.35,0.318,0,0,-1.7,0.5
ENSMUSG00000032652,CREBL2,cAMP responsive element binding protein-like 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell differentiation|positive regulation of peptidyl-serine phosphorylation|positive regulation of fat cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of glucose import|positive regulation of lipid biosynthetic process|protein stabilization|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.2,1.23,10,-0.2,1.27,-0.2,2.32,-2.32,0.322,0,0,-1.6,0.5
ENSMUSG00000032374,PLOD2,"procollagen lysine, 2-oxoglutarate 5-dioxygenase 2",endoplasmic reticulum|membrane|extracellular vesicular exosome|,oxidation-reduction process|,"iron ion binding|procollagen-lysine 5-dioxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|L-ascorbic acid binding|metal ion binding|dioxygenase activity|",10,-0.3,2.88,10,-0.1,0.167,-0.3,2.32,-2.32,0.322,0,0,-1.5,0.5
ENSMUSG00000022194,PABPN1,"poly(A) binding protein, nuclear 1",nucleus|cytoplasm|ribonucleoprotein complex|,mRNA polyadenylation|mRNA processing|poly(A)+ mRNA export from nucleus|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) binding|poly(A) RNA binding|,4,0.8,3.66,3,-0.2,0.123,0.7,2.31,2.31,0.323,0,0,-1.2,2
ENSMUSG00000038167,PLEKHG6,"pleckstrin homology domain containing, family G (with RhoGef domain) member 6",cellular_component|cytoplasm|cytoskeleton|,biological_process|regulation of Rho protein signal transduction|,molecular_function|Rho guanyl-nucleotide exchange factor activity|GTPase activator activity|,10,0.4,3.15,10,0.1,0.541,0.2,2.28,2.28,0.326,0,0,-0.4,1.5
ENSMUSG00000020888,DVL2,"dishevelled 2, dsh homolog (Drosophila)",nucleus|cytoplasm|cytoplasm|cytosol|cytoskeleton|plasma membrane|plasma membrane|cell cortex|cell cortex|membrane|clathrin-coated vesicle|cytoplasmic vesicle|apical part of cell|,"neural tube closure|positive regulation of protein phosphorylation|heart morphogenesis|outflow tract morphogenesis|transcription from RNA polymerase II promoter|multicellular organismal development|segment specification|heart development|Wnt signaling pathway|Wnt signaling pathway|Wnt signaling pathway|cell migration in hindbrain|convergent extension involved in neural plate elongation|convergent extension involved in neural plate elongation|cellular protein localization|segmentation|intracellular signal transduction|non-canonical Wnt signaling pathway|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|canonical Wnt signaling pathway involved in regulation of cell proliferation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|regulation of JNK cascade|positive regulation of sequence-specific DNA binding transcription factor activity|convergent extension involved in organogenesis|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|positive regulation of protein tyrosine kinase activity|cochlea morphogenesis|planar cell polarity pathway involved in neural tube closure|planar cell polarity pathway involved in neural tube closure|positive regulation of canonical Wnt signaling pathway|",frizzled binding|frizzled binding|frizzled binding|protein binding|protein domain specific binding|identical protein binding|identical protein binding|protein self-association|,10,0.2,1.11,10,0.2,1.34,0.2,2.27,2.27,0.328,0,0,-0.6,1.5
ENSMUSG00000059772,SLX1B,SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae),nucleus|Slx1-Slx4 complex|,"DNA catabolic process, endonucleolytic|DNA repair|DNA recombination|cellular response to DNA damage stimulus|","nuclease activity|endonuclease activity|thiamine-pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|crossover junction endodeoxyribonuclease activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|5'-flap endonuclease activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|",10,0.4,1.99,10,0.4,0.432,0.4,2.27,2.27,0.328,0,0,-0.5,1.6
ENSMUSG00000050213,SNIP1,Smad nuclear interacting protein 1,nucleus|,"regulation of transcription, DNA-templated|I-kappaB kinase/NF-kappaB signaling|gene silencing by RNA|production of miRNAs involved in gene silencing by miRNA|",protein binding|poly(A) RNA binding|,9,-0.3,3.74,10,0.4,3.09,-0.2,2.26,-2.26,0.328,0,0,-1,1.3
ENSMUSG00000037692,AHDC1,"AT hook, DNA binding motif, containing 1",cellular_component|,biological_process|,molecular_function|DNA binding|,10,-0.4,1.87,10,-0.2,0.849,-0.4,2.24,-2.24,0.331,0,0,-1.5,0.8
ENSMUSG00000034551,HDX,highly divergent homeobox,cellular_component|nucleus|,biological_process|,DNA binding|,10,0.4,3.34,10,-0.1,0.366,0.4,2.23,2.23,0.332,0,0,-0.9,1.6
ENSMUSG00000030393,ZIK1,zinc finger protein interacting with K protein 1,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.3,1.33,10,-0.2,1.09,-0.3,2.22,-2.22,0.333,0,0,-1.4,1
ENSMUSG00000003505,PSG18,pregnancy specific glycoprotein 18,None,female pregnancy|cytokinin biosynthetic process|positive regulation of gene expression|regulation of interleukin-10 secretion|,None,10,0,0,10,-0.5,3.77,-0.3,2.2,-2.2,0.335,0,0,-1.7,0.5
ENSMUSG00000030507,DBX1,developing brain homeobox 1,nucleus|,"regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|ventral spinal cord interneuron specification|",DNA binding|sequence-specific DNA binding|,10,-0.2,2.01,10,0.2,0.47,-0.2,2.2,-2.2,0.335,0,0,-1.2,1.1
ENSMUSG00000062296,TRANK1,tetratricopeptide repeat and ankyrin repeat containing 1,cellular_component|,biological_process|,molecular_function|ATP binding|hydrolase activity|,10,0.2,0.68,10,0.7,3.26,0.6,2.19,2.19,0.337,0,0,-0.2,1.8
ENSMUSG00000066839,ECSIT,ECSIT homolog (Drosophila),nucleus|transcription factor complex|cytoplasm|mitochondrion|mitochondrion|,mesoderm formation|immune system process|regulation of transcription from RNA polymerase II promoter|transmembrane receptor protein serine/threonine kinase signaling pathway|transmembrane receptor protein serine/threonine kinase signaling pathway|BMP signaling pathway|innate immune response|regulation of oxidoreductase activity|oxidation-reduction process|,"sequence-specific DNA binding transcription factor activity|signal transducer activity|protein binding|oxidoreductase activity, acting on NAD(P)H|",10,0.1,0.0133,10,0.7,4.41,0.6,2.18,2.18,0.338,0,0,-0.4,1.9
ENSMUSG00000016018,SKIV2L2,superkiller viralicidic activity 2-like 2 (S. cerevisiae),exosome (RNase complex)|nucleus|spliceosomal complex|catalytic step 2 spliceosome|,maturation of 5.8S rRNA|rRNA processing|mRNA processing|RNA splicing|,"nucleotide binding|nucleic acid binding|helicase activity|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|poly(A) RNA binding|",8,0,0,8,0.4,2.98,0.3,2.17,2.17,0.339,0,0,-0.8,1.7
ENSMUSG00000028358,ZFP618,zinc finger protein 618,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0.4,3.86,0.4,2.16,2.16,0.34,0,0,-0.8,1.5
ENSMUSG00000047534,MIS18BP1,MIS18 binding protein 1,"chromosome, centromeric region|cellular_component|nucleus|chromosome|",cell cycle|mitotic nuclear division|biological_process|cell division|,DNA binding|chromatin binding|protein binding|,10,1,2.52,10,-0.8,1.48,-0.9,2.15,-2.15,0.341,0,0,-1.9,1.4
ENSMUSG00000063506,ARHGAP22,Rho GTPase activating protein 22,intracellular|nucleus|cytoplasm|,"angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|multicellular organismal development|cell differentiation|",molecular_function|GTPase activator activity|,10,0.2,0.683,10,0.2,1.62,0.2,2.14,2.14,0.343,0,0,-0.4,1.7
ENSMUSG00000067220,CNGA1,cyclic nucleotide gated channel alpha 1,photoreceptor outer segment|cytoplasm|integral component of plasma membrane|membrane|integral component of membrane|intracellular cyclic nucleotide activated cation channel complex|photoreceptor outer segment membrane|terminal bouton|,"transport|ion transport|cation transport|visual perception|phototransduction, visible light|ion transmembrane transport|regulation of ion transmembrane transport|regulation of membrane potential|response to stimulus|cytosolic calcium ion homeostasis|membrane depolarization|transmembrane transport|potassium ion transmembrane transport|",nucleotide binding|ion channel activity|intracellular cAMP activated cation channel activity|intracellular cGMP activated cation channel activity|intracellular cGMP activated cation channel activity|voltage-gated potassium channel activity|cGMP binding|cGMP binding|,10,-0.4,2.34,10,-0.1,0.24,-0.3,2.14,-2.14,0.343,0,0,-1.4,1
ENSMUSG00000039117,TAF4A,"TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|cytoplasm|transcription factor TFTC complex|MLL1 complex|,"ovarian follicle development|DNA-templated transcription, initiation|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.4,1.7,10,-0.2,0.962,-0.3,2.13,-2.13,0.344,0,0,-1.5,0.6
ENSMUSG00000025019,LCOR,ligand dependent nuclear receptor corepressor,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|,9,-0.3,0.87,10,0.3,2.86,0.2,2.13,2.13,0.344,0,0,-1,1.4
ENSMUSG00000053580,TANC2,"tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2",cellular_component|,in utero embryonic development|,molecular_function|,10,0.2,0.433,10,0.2,1.84,0.2,2.12,2.12,0.345,0,0,-0.9,1.4
ENSMUSG00000037001,ZFP39,zinc finger protein 39,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|biological_process|cell differentiation|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.4,1.28,10,0.2,2.63,0.2,2.11,2.11,0.346,0,0,-1.2,1.2
ENSMUSG00000053286,TRMT1L,tRNA methyltransferase 1 like,None,behavior|tRNA processing|adult locomotory behavior|adult behavior|methylation|,"tRNA binding|rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,0.668,10,-0.3,1.65,-0.2,2.09,-2.09,0.349,0,0,-1.4,0.8
ENSMUSG00000022503,NUBP1,nucleotide binding protein 1,cytoplasm|cytosol|plasma membrane|extracellular vesicular exosome|,cellular iron ion homeostasis|negative regulation of centrosome duplication|cell growth|iron-sulfur cluster assembly|centrosome localization|protein localization to cell cortex|,"nucleotide binding|protein binding|ATP binding|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",8,0.6,1.64,9,-0.2,1.34,-0.3,2.08,-2.08,0.35,0,0,-1.1,1.4
ENSMUSG00000038290,SMG6,"Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)","chromosome, telomeric region|nucleus|chromosome|nucleolus|cytoplasm|cytosol|exon-exon junction complex|","nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|telomere maintenance|RNA phosphodiester bond hydrolysis, endonucleolytic|",DNA binding|nuclease activity|endonuclease activity|endoribonuclease activity|hydrolase activity|telomeric DNA binding|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,-0.5,1.74,10,0.3,1.09,-0.3,2.06,-2.06,0.353,0,0,-1.4,1.3
ENSMUSG00000026889,RBM18,RNA binding motif protein 18,cellular_component|,biological_process|,nucleotide binding|molecular_function|nucleic acid binding|RNA binding|,9,0.9,2.37,9,-0.8,2.29,0.9,2.06,2.06,0.353,0,0,-1.3,2
ENSMUSG00000029012,ORC5,"origin recognition complex, subunit 5",origin recognition complex|nucleus|nuclear origin of replication recognition complex|cytoplasm|,DNA replication|,nucleotide binding|ATP binding|,8,-1.1,4.65,8,0.9,3.01,-1.1,2.06,-2.06,0.353,0,0,-2,1.3
ENSMUSG00000060739,NSA2,NSA2 ribosome biogenesis homolog (S. cerevisiae),cellular_component|nucleus|ribonucleoprotein complex|,rRNA processing|biological_process|ribosome biogenesis|,poly(A) RNA binding|,10,0.2,1.03,10,0.3,1.31,0.2,2.04,2.04,0.355,0,0,-1,1.6
ENSMUSG00000050100,HMX2,H6 homeobox 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|brain development|positive regulation of cell proliferation|cell differentiation|inner ear morphogenesis|inner ear morphogenesis|",DNA binding|sequence-specific DNA binding|,10,0.1,0.057,10,0.3,2.53,0.2,1.99,1.99,0.362,0,0,-0.6,1.5
ENSMUSG00000026843,FUBP3,far upstream element (FUSE) binding protein 3,nucleus|cytoplasm|membrane|,"transcription, DNA-templated|positive regulation of gene expression|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",single-stranded DNA binding|poly(A) RNA binding|,10,0,0,10,0.4,3.23,0.3,1.99,1.99,0.362,0,0,-0.6,1.6
ENSMUSG00000057098,EBF1,early B cell factor 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|protein dimerization activity|C2H2 zinc finger domain binding|,10,0.2,0.077,10,-0.6,3.62,-0.5,1.98,-1.98,0.363,0,0,-1.9,0.5
ENSMUSG00000003452,BICD1,bicaudal D homolog 1 (Drosophila),cell|Golgi apparatus|trans-Golgi network|cytosol|cytoplasmic microtubule|membrane|cytoplasmic vesicle|perinuclear region of cytoplasm|host cell viral assembly compartment|,transport|viral process|protein localization to organelle|stress granule assembly|positive regulation of receptor-mediated endocytosis|minus-end-directed organelle transport along microtubule|microtubule anchoring at microtubule organizing center|negative regulation of phospholipase C activity|regulation of proteinase activated receptor activity|negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|,cytoskeletal adaptor activity|Rab GTPase binding|proteinase activated receptor binding|proteinase activated receptor binding|dynactin binding|dynein binding|,10,-0.1,0.116,10,-0.3,2.19,-0.3,1.97,-1.97,0.364,0,0,-1.7,0.5
ENSMUSG00000038766,GABPB2,"GA repeat binding protein, beta 2",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",protein homodimerization activity|transcription regulatory region DNA binding|protein heterodimerization activity|,10,-0.2,1.44,10,-0.2,0.669,-0.2,1.96,-1.96,0.366,0,0,-1.5,0.7
ENSMUSG00000041530,AGO1,argonaute RISC catalytic subunit 1,cytoplasmic mRNA processing body|cytoplasm|polysome|ribonucleoprotein complex|micro-ribonucleoprotein complex|micro-ribonucleoprotein complex|,"nuclear-transcribed mRNA catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|gene silencing by RNA|negative regulation of translation involved in gene silencing by miRNA|",nucleic acid binding|RNA binding|RNA binding|protein binding|poly(A) RNA binding|,10,-0.3,2.05,10,-0.1,0.467,-0.2,1.95,-1.95,0.367,0,0,-1.4,0.9
ENSMUSG00000051224,TCEANC,transcription elongation factor A (SII) N-terminal and central domain containing,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of DNA-templated transcription, elongation|",molecular_function|DNA binding|,10,0.2,1.53,10,1.2,2.96,0.3,1.95,1.95,0.367,0,0,-0.1,2
ENSMUSG00000018698,LHX1,LIM homeobox protein 1,intracellular|nucleus|nucleus|protein complex|,"urogenital system development|ureteric bud development|gastrulation with mouth forming second|ectoderm formation|endoderm formation|kidney development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell-cell signaling|multicellular organismal development|pattern specification process|pattern specification process|nervous system development|motor neuron axon guidance|anatomical structure morphogenesis|post-embryonic development|embryonic pattern specification|anterior/posterior axis specification|anterior/posterior pattern specification|dorsal/ventral pattern formation|regulation of gene expression|retina layer formation|spinal cord association neuron differentiation|cerebellum development|cerebellar Purkinje cell differentiation|forebrain regionalization|cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation|cell differentiation|somite rostral/caudal axis specification|oviduct epithelium development|uterine epithelium development|nephric duct elongation|horizontal cell localization|positive regulation of embryonic development|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|anatomical structure formation involved in morphogenesis|anatomical structure formation involved in morphogenesis|embryonic viscerocranium morphogenesis|embryonic retina morphogenesis in camera-type eye|uterus development|oviduct development|cervix development|vagina development|head development|epithelium development|paramesonephric duct development|renal system development|comma-shaped body morphogenesis|S-shaped body morphogenesis|renal vesicle morphogenesis|nephric duct morphogenesis|primitive streak formation|positive regulation of branching involved in ureteric bud morphogenesis|lateral motor column neuron migration|positive regulation of gastrulation|positive regulation of anterior head development|positive regulation of nephron tubule epithelial cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,9,0,0,10,1,3.59,0.9,1.93,1.93,0.37,0,0,-0.1,2
ENSMUSG00000007946,PHOX2A,paired-like homeobox 2a,nuclear chromatin|nucleus|,"noradrenergic neuron differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|somatic motor neuron differentiation|oculomotor nerve formation|trochlear nerve formation|locus ceruleus development|midbrain development|regulation of respiratory gaseous exchange|positive regulation of transcription from RNA polymerase II promoter|sympathetic nervous system development|parasympathetic nervous system development|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|,10,0.3,2.29,10,-1,3.33,0.2,1.9,1.9,0.373,0,0,-2,0.7
ENSMUSG00000020547,BZW2,basic leucine zipper and W2 domains 2,membrane|,multicellular organismal development|nervous system development|biological_process|cell differentiation|,molecular_function|,10,0.2,0.306,10,0.8,2.27,0.2,1.9,1.9,0.373,0,0,-0.5,1.9
ENSMUSG00000040321,ZFP770,zinc finger protein 770,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.9,4.22,-0.6,1.89,-1.89,0.375,0,0,-2,0.1
ENSMUSG00000036611,EEPD1,endonuclease/exonuclease/phosphatase family domain containing 1,cellular_component|,DNA repair|biological_process|,DNA binding|,10,0.3,0.851,10,0.2,1.2,0.3,1.88,1.88,0.377,0,0,-1,1.4
ENSMUSG00000019897,CCDC59,coiled-coil domain containing 59,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",poly(A) RNA binding|,10,0.3,0.152,10,-0.5,2.31,-0.4,1.87,-1.87,0.378,0,0,-1.4,1.3
ENSMUSG00000028886,EYA3,eyes absent 3 homolog (Drosophila),nucleus|nucleus|transcription factor complex|cytoplasm|,"DNA repair|double-strand break repair|transcription, DNA-templated|regulation of transcription, DNA-templated|protein dephosphorylation|cellular response to DNA damage stimulus|multicellular organismal development|response to ionizing radiation|chromatin modification|histone dephosphorylation|peptidyl-tyrosine dephosphorylation|peptidyl-tyrosine dephosphorylation|positive regulation of DNA repair|",chromatin binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine phosphatase activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|metal ion binding|,10,-0.3,4.13,10,0,0,-0.3,1.86,-1.86,0.379,0,0,-1.5,0.7
ENSMUSG00000043300,B3GALNT1,"UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1",Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|oligosaccharide biosynthetic process|,"galactosyltransferase activity|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity|",10,-0.1,0.516,10,-0.2,1.53,-0.2,1.86,-1.86,0.379,0,0,-1.7,0.6
ENSMUSG00000031568,RWDD4A,RWD domain containing 4A,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.44,10,-0.2,0.547,-0.2,1.84,-1.84,0.382,0,0,-1.7,0.5
ENSMUSG00000020052,ASCL1,achaete-scute complex homolog 1 (Drosophila),nucleus|nucleus|neuronal cell body|,"neuron migration|neuron migration|noradrenergic neuron development|noradrenergic neuron fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|regulation of mitotic cell cycle|pattern specification process|nervous system development|neuroblast fate determination|neuroblast proliferation|regulation of Notch signaling pathway|glial cell differentiation|regulation of gene expression|oligodendrocyte development|spinal cord association neuron differentiation|spinal cord oligodendrocyte cell differentiation|spinal cord oligodendrocyte cell fate specification|vestibular nucleus development|oligodendrocyte cell fate commitment|forebrain neuron differentiation|commitment of neuronal cell to specific neuron type in forebrain|central nervous system neuron development|central nervous system neuron development|cerebral cortex development|neurogenesis|neurogenesis|cell differentiation|neuron differentiation|neuron differentiation|regulation of epithelial cell differentiation|regulation of cell proliferation|negative regulation of apoptotic process|positive regulation of neuron apoptotic process|negative regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of Notch signaling pathway|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|enteric nervous system development|sympathetic nervous system development|parasympathetic nervous system development|neuron fate commitment|neuron fate commitment|neuron fate specification|neuron development|generation of neurons|oligodendrocyte differentiation|regulation of neurogenesis|positive regulation of neurogenesis|musculoskeletal movement, spinal reflex action|subpallium neuron fate commitment|regulation of timing of subpallium neuron differentiation|olfactory pit development|ventral spinal cord interneuron fate commitment|lung neuroendocrine cell differentiation|stomach neuroendocrine cell differentiation|carotid body glomus cell differentiation|adrenal chromaffin cell differentiation|sympathetic ganglion development|positive regulation of neural precursor cell proliferation|",transcription factor binding transcription factor activity|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|bHLH transcription factor binding|sequence-specific DNA binding|protein dimerization activity|E-box binding|,10,-0.5,3.47,10,0,0,-0.5,1.83,-1.83,0.384,0,0,-1.7,0.4
ENSMUSG00000025475,GPR123,G protein-coupled receptor 123,plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.32,10,0.2,0.646,0.2,1.82,1.82,0.386,0,0,-1.9,0.9
ENSMUSG00000028729,EBNA1BP2,EBNA1 binding protein 2,nucleus|nucleolus|nucleolus|,rRNA processing|chromosome segregation|ribosome biogenesis|,poly(A) RNA binding|,10,-0.3,1.3,8,-0.6,0.904,-0.4,1.81,-1.81,0.387,0,0,-1.7,1.1
ENSMUSG00000038069,CDKN2AIP,CDKN2A interacting protein,granular component|nucleus|nucleus|nucleoplasm|nucleolus|cytoplasm|,positive regulation of signal transduction|negative regulation of cell growth|regulation of protein stability|,p53 binding|RNA binding|,10,0.2,0.29,10,-0.3,2.12,0.6,1.81,1.81,0.387,0,0,-0.7,1.8
ENSMUSG00000042109,CSDC2,"cold shock domain containing C2, RNA binding",nucleus|cytoplasm|,"regulation of transcription, DNA-templated|mRNA processing|biological_process|",nucleic acid binding|DNA binding|RNA binding|,10,0.3,0.605,10,0.3,1.33,0.3,1.8,1.8,0.389,0,0,-0.5,1.6
ENSMUSG00000046714,FOXC2,forkhead box C2,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|skeletal system development|skeletal system development|ossification|blood vessel development|patterning of blood vessels|metanephros development|ureteric bud development|somitogenesis|kidney development|lymph vessel development|lymphangiogenesis|lymphangiogenesis|blood vessel remodeling|heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|Notch signaling pathway|multicellular organismal development|heart development|heart development|heart development|cell proliferation|insulin receptor signaling pathway|insulin receptor signaling pathway|response to hormone|response to hormone|positive regulation of endothelial cell migration|neural crest cell development|collagen fibril organization|positive regulation of integrin activation|positive regulation of cell adhesion mediated by integrin|embryonic heart tube development|positive regulation of vascular wound healing|camera-type eye development|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of organ growth|vascular endothelial growth factor receptor signaling pathway|paraxial mesoderm formation|paraxial mesodermal cell fate commitment|embryonic cranial skeleton morphogenesis|embryonic viscerocranium morphogenesis|embryonic skeletal system morphogenesis|artery morphogenesis|regulation of blood vessel size|ventricular cardiac muscle tissue morphogenesis|cardiac muscle cell proliferation|glomerular endothelium development|glomerular visceral epithelial cell differentiation|glomerular mesangial cell development|positive regulation of cell migration involved in sprouting angiogenesis|negative regulation of apoptotic process involved in outflow tract morphogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|chromatin DNA binding|chromatin DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.3,2.04,10,0.1,0.199,0.2,1.79,1.79,0.39,0,0,-0.6,1.6
ENSMUSG00000034297,MED13,mediator complex subunit 13,nucleus|membrane|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|transcription cofactor activity|transcription coactivator activity|receptor activity|thyroid hormone receptor binding|,10,-0.4,2.45,9,0.4,3.16,0.4,1.78,1.78,0.392,0,0,-1.1,1.4
ENSMUSG00000045252,ZFP574,zinc finger protein 574,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,9,-0.3,1.82,9,-0.1,0.361,-0.2,1.77,-1.77,0.393,0,0,-1.5,1.1
ENSMUSG00000020171,YEATS4,YEATS domain containing 4,nucleus|nucleoplasm|nucleoplasm|NuA4 histone acetyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|regulation of growth|histone H4 acetylation|histone H2A acetylation|",protein binding|protein C-terminus binding|,10,0,0,10,0.3,2.39,0.3,1.76,1.76,0.395,0,0,-1,1.4
ENSMUSG00000032239,RP9,retinitis pigmentosa 9 (human),nucleus|signal recognition particle receptor complex|nuclear speck|,cognition|,nucleic acid binding|protein binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.1,0.424,10,-0.3,1.87,-0.2,1.74,-1.74,0.397,0,0,-1.8,0.4
ENSMUSG00000055341,ZFP457,zinc finger protein 457,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.0682,10,0.3,2.13,0.2,1.73,1.73,0.399,0,0,-0.4,1.8
ENSMUSG00000024497,POU4F3,"POU domain, class 4, transcription factor 3",nucleus|nucleus|transcription factor complex|,"regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|sensory perception of sound|sensory perception of sound|vestibulocochlear nerve development|retinal ganglion cell axon guidance|inner ear morphogenesis|auditory receptor cell differentiation|positive regulation of transcription from RNA polymerase II promoter|axon extension|inner ear development|neuromuscular process controlling balance|neuromuscular process controlling balance|neuron apoptotic process|inner ear receptor cell differentiation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.4,3.77,10,0,0,0.3,1.72,1.72,0.401,0,0,-0.4,1.6
ENSMUSG00000000823,ZNF512B,zinc finger protein 512B,None,biological_process|,molecular_function|,10,0,0,10,0.2,2.72,0.2,1.71,1.71,0.402,0,0,-0.9,1.5
ENSMUSG00000041815,POLDIP3,"polymerase (DNA-directed), delta interacting protein 3",transcription export complex|intracellular|cell|nucleus|cytoplasm|nuclear speck|exon-exon junction complex|,regulation of translation|transport|poly(A)+ mRNA export from nucleus|poly(A)+ mRNA export from nucleus|positive regulation of translation|mRNA transport|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.5,1.18,10,-0.3,0.843,-0.5,1.7,-1.7,0.403,0,0,-1.7,0.8
ENSMUSG00000034758,TLE6,"transducin-like enhancer of split 6, homolog of Drosophila E(spl)",cytoplasm|cell cortex|protein complex|,None,protein binding|,10,-1,1.42,10,-0.3,1.6,-0.4,1.67,-1.67,0.408,0,0,-2,0.2
ENSMUSG00000033849,B3GALT2,"UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2",cellular_component|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|oligosaccharide biosynthetic process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.3,0.803,10,-0.3,1.89,-0.3,1.66,-1.66,0.41,0,0,-1.3,1.3
ENSMUSG00000054079,UTP18,"UTP18, small subunit (SSU) processome component, homolog (yeast)",nucleus|nucleolus|,rRNA processing|biological_process|,poly(A) RNA binding|,10,0.2,0.885,10,-0.8,4.23,0.2,1.64,1.64,0.412,0,0,-1.8,1
ENSMUSG00000028772,ZCCHC17,"zinc finger, CCHC domain containing 17",nucleus|nucleolus|cytosolic large ribosomal subunit|ribonucleoprotein complex|,None,nucleic acid binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.4,0.874,10,-0.8,1.33,-0.4,1.62,-1.62,0.416,0,0,-1.8,0.9
ENSMUSG00000030204,DDX47,DEAD (Asp-Glu-Ala-Asp) box polypeptide 47,nucleus|nucleolus|membrane|,rRNA processing|mRNA processing|apoptotic process|RNA splicing|extrinsic apoptotic signaling pathway via death domain receptors|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,0,0,10,-0.7,2.64,-0.5,1.6,-1.6,0.419,0,0,-1.7,1.8
ENSMUSG00000031107,RBMX2,"RNA binding motif protein, X-linked 2",cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,9,0.4,2.52,10,-0.1,0.306,0.4,1.6,1.6,0.419,0,0,-0.9,1.6
ENSMUSG00000054737,ZFP182,zinc finger protein 182,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,2.39,10,0,0,-0.2,1.6,-1.6,0.419,0,0,-1.5,0.9
ENSMUSG00000044791,SETD2,SET domain containing 2,nucleus|chromosome|,"angiogenesis|vasculogenesis|morphogenesis of a branching structure|neural tube closure|mismatch repair|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription elongation from RNA polymerase II promoter|histone H3-K36 methylation|regulation of gene expression|regulation of mRNA export from nucleus|chromatin modification|peptidyl-lysine trimethylation|forebrain development|methylation|nucleosome organization|histone lysine methylation|cell migration involved in vasculogenesis|mesoderm morphogenesis|embryonic organ development|embryonic cranial skeleton morphogenesis|stem cell development|pericardium development|embryonic placenta morphogenesis|coronary vasculature morphogenesis|histone H3-K36 trimethylation|",methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|,10,-1.1,1.01,10,-0.4,2.35,-1,1.59,-1.59,0.421,0,0,-2,0.4
ENSMUSG00000019297,NOP9,NOP9 nucleolar protein,cellular_component|,biological_process|,RNA binding|poly(A) RNA binding|,10,-1,1.16,10,0.6,2.16,0.6,1.56,1.56,0.426,0,0,-1.6,1.6
ENSMUSG00000036686,CC2D1A,coiled-coil and C2 domain containing 1A,nucleus|cytoplasm|membrane|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|signal transducer activity|,10,0.3,3.56,10,-0.1,0.118,0.3,1.56,1.56,0.426,0,0,-1.1,1.4
ENSMUSG00000031621,ISX,intestine specific homeobox,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of vitamin A metabolic process|",DNA binding|sequence-specific DNA binding|,10,0.1,0.467,10,0.2,1.48,0.2,1.55,1.55,0.427,0,0,-1,1.5
ENSMUSG00000021936,MAPK8,mitogen-activated protein kinase 8,nucleus|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|cytosol|axon|vesicle|dendrite cytoplasm|perikaryon|,"ossification|regulation of transcription, DNA-templated|protein phosphorylation|inflammatory response|response to osmotic stress|signal transduction|JNK cascade|JNK cascade|JUN phosphorylation|JUN phosphorylation|JUN phosphorylation|response to heat|response to UV|regulation of gene expression|positive regulation of gene expression|phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|peptidyl-threonine phosphorylation|positive regulation of cell migration|regulation of histone deacetylation|positive regulation of microtubule polymerization|neuron projection development|negative regulation of protein binding|regulation of protein localization|response to hydrogen peroxide|negative regulation of apoptotic process|positive regulation of DNA replication|response to cadmium ion|determination of dorsal identity|cellular response to hydrogen peroxide|cellular response to lipopolysaccharide|cellular response to nitric oxide|positive regulation of deacetylase activity|programmed necrotic cell death|positive regulation of determination of dorsal identity|positive regulation of apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|JUN kinase activity|JUN kinase activity|MAP kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|histone deacetylase regulator activity|histone deacetylase binding|",10,-0.2,1.59,10,-0.1,0.323,-0.2,1.53,-1.53,0.431,0,0,-1.4,1.6
ENSMUSG00000050714,ZBTB26,zinc finger and BTB domain containing 26,cellular_component|nucleus|,biological_process|,molecular_function|metal ion binding|,9,-0.7,3.94,9,0,0,-0.6,1.53,-1.53,0.431,0,0,-1.9,0.4
ENSMUSG00000058392,RRP1B,ribosomal RNA processing 1 homolog B (S. cerevisiae),"euchromatin|heterochromatin|nucleus|nucleus|nucleolus|cytosol|preribosome, small subunit precursor|",rRNA processing|negative regulation of phosphatase activity|,protein binding|poly(A) RNA binding|,10,0.8,3.64,10,-0.1,0.00812,0.5,1.51,1.51,0.434,0,0,-0.5,2
ENSMUSG00000078897,GM4724,predicted gene 4724,cellular_component|,biological_process|,molecular_function|,9,0.2,1.16,9,0.2,0.47,0.2,1.51,1.51,0.434,0,0,-0.7,1.8
ENSMUSG00000078880,GM14308,predicted gene 14308,cellular_component|,biological_process|,molecular_function|,9,0.2,1.16,9,0.2,0.47,0.2,1.51,1.51,0.434,0,0,-0.7,1.8
ENSMUSG00000078881,GM14434,predicted gene 14434,cellular_component|,biological_process|,molecular_function|,9,0.2,1.16,9,0.2,0.47,0.2,1.51,1.51,0.434,0,0,-0.7,1.8
ENSMUSG00000044030,IRF2BP1,interferon regulatory factor 2 binding protein 1,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|","transcription corepressor activity|transcription factor binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.3,0.922,10,-0.3,0.699,-0.3,1.5,-1.5,0.436,0,0,-1.5,0.9
ENSMUSG00000074406,ZFP628,zinc finger protein 628,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,1.21,10,0.9,3.59,-0.2,1.49,-1.49,0.437,0,0,-0.5,2
ENSMUSG00000044475,ASCC1,activating signal cointegrator 1 complex subunit 1,transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",transcription coactivator activity|RNA binding|catalytic activity|,10,-0.1,0.286,10,-0.5,2.1,-0.2,1.45,-1.45,0.444,0,0,-1.6,1.2
ENSMUSG00000027387,ZC3H8,zinc finger CCCH type containing 8,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|negative regulation of T cell differentiation in thymus|T cell homeostasis|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|response to antibiotic|positive regulation of thymocyte apoptotic process|",sequence-specific DNA binding transcription factor activity|RNA binding|sequence-specific DNA binding|poly(A) RNA binding|metal ion binding|,10,-0.1,0.142,10,0.3,2.53,0.2,1.43,1.43,0.447,0,0,-0.8,1.6
ENSMUSG00000028150,RORC,RAR-related orphan receptor gamma,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|xenobiotic metabolic process|multicellular organismal development|regulation of glucose metabolic process|regulation of steroid metabolic process|cell differentiation|circadian regulation of gene expression|T cell differentiation in thymus|cellular response to sterol|T-helper cell differentiation|positive regulation of circadian rhythm|steroid hormone mediated signaling pathway|regulation of gamma-delta T cell differentiation|regulation of fat cell differentiation|alpha-beta T cell differentiation|rhythmic process|lymph node development|mucosal-associated lymphoid tissue development|Peyer's patch development|adipose tissue development|regulation of transcription involved in cell fate commitment|negative regulation of thymocyte apoptotic process|T-helper 17 cell differentiation|T-helper 17 cell differentiation|",transcription coactivator binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|oxysterol binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|direct ligand regulated sequence-specific DNA binding transcription factor activity|,10,-0.3,1.77,10,-0.1,0.0964,-0.2,1.43,-1.43,0.447,0,0,-1.9,0.4
ENSMUSG00000062808,HIST1H3D,"histone cluster 1, H3d",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,molecular_function|,8,-0.9,1.52,7,-0.4,1.27,-0.4,1.42,-1.42,0.449,0,0,-2,0.6
ENSMUSG00000027510,RBM38,RNA binding motif protein 38,nucleus|cytoplasm|cytosol|,"mRNA processing|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cell cycle|negative regulation of cell proliferation|RNA splicing|regulation of myotube differentiation|cell differentiation|regulation of RNA splicing|3'-UTR-mediated mRNA stabilization|",nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|mRNA binding|mRNA 3'-UTR binding|poly(A) RNA binding|,10,-0.1,0.17,10,-0.4,1.88,-0.4,1.4,-1.4,0.453,0,0,-1.7,0.7
ENSMUSG00000033669,ZFP7,zinc finger protein 7,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.5,1.22,10,-0.2,0.77,-0.2,1.36,-1.36,0.46,0,0,-1.7,0.6
ENSMUSG00000017999,DDX27,DEAD (Asp-Glu-Ala-Asp) box polypeptide 27,cellular_component|nucleus|,biological_process|,nucleotide binding|nucleic acid binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,-0.8,2.86,10,0.9,3.44,0.2,1.36,1.36,0.46,0,0,-1.3,1.9
ENSMUSG00000030678,MAZ,MYC-associated zinc finger protein (purine-binding transcription factor),nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|termination of RNA polymerase II transcription|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|chromatin binding|protein binding|poly(A) RNA binding|metal ion binding|,10,-0.1,1.02,10,-0.1,0.444,-0.1,1.35,-1.35,0.462,0,0,-1.6,1
ENSMUSG00000033326,KDM4A,lysine (K)-specific demethylase 4A,nucleus|nucleolus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cardiac muscle hypertrophy in response to stress|chromatin modification|histone demethylation|negative regulation of transcription, DNA-templated|oxidation-reduction process|histone H3-K36 demethylation|","sulfonate dioxygenase activity|zinc ion binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|ubiquitin protein ligase binding|hypophosphite dioxygenase activity|methylated histone binding|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|histone demethylase activity (H3-K36 specific)|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",9,-0.2,1.2,9,0.2,1.88,0.2,1.34,1.34,0.464,0,0,-1.2,1.4
ENSMUSG00000006019,DHX34,DEAH (Asp-Glu-Ala-His) box polypeptide 34,membrane|,"nuclear-transcribed mRNA catabolic process|negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|",nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,0.1,0.0157,10,0.5,3.05,0.4,1.34,1.34,0.464,0,0,-0.9,1.7
ENSMUSG00000031167,RBM3,RNA binding motif protein 3,nucleus|cytoplasm|large ribosomal subunit|dendrite|cell projection|,translation|regulation of translation|response to stress|response to cold|production of miRNAs involved in gene silencing by miRNA|positive regulation of translation|,nucleotide binding|nucleic acid binding|RNA binding|ribosomal large subunit binding|poly(A) RNA binding|,10,0.1,0.85,10,0.4,0.93,0.2,1.34,1.34,0.464,0,0,-0.6,1.8
ENSMUSG00000060461,DPPA5A,developmental pluripotency associated 5A,cytoplasm|,multicellular organismal development|regulation of gene expression|,RNA binding|mRNA binding|,9,0.4,2.53,9,0.1,0.333,0.2,1.33,1.33,0.465,0,0,-0.7,1.9
ENSMUSG00000057691,ZFP746,zinc finger protein 746,intracellular|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of cell death|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|neuron death|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|ubiquitin protein ligase binding|ubiquitin protein ligase binding|transcription regulatory region DNA binding|metal ion binding|,10,1,1.25,10,0.2,1.19,0.3,1.3,1.3,0.471,0,0,-1,2
ENSMUSG00000023947,NFKBIE,"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon",cytoplasm|Golgi apparatus|perinuclear region of cytoplasm|,"D-serine transport|negative regulation of transcription, DNA-templated|",protein binding|,10,0.1,0.019,10,-0.3,2.44,-0.3,1.29,-1.29,0.473,0,0,-1.8,0.6
ENSMUSG00000029290,ZFP326,zinc finger protein 326,nucleus|spliceosomal complex|nuclear matrix|DBIRD complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|regulation of DNA-templated transcription, elongation|positive regulation of transcription, DNA-templated|",RNA polymerase II core binding|DNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,9,0.2,0.893,9,0.1,0.548,0.2,1.28,1.28,0.475,0,0,-1.6,1.3
ENSMUSG00000026135,ZFP142,zinc finger protein 142,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.389,10,0.4,1.57,0.3,1.27,1.27,0.477,0,0,-1.3,1.3
ENSMUSG00000036249,RBM43,RNA binding motif protein 43,cellular_component|,biological_process|,molecular_function|nucleic acid binding|RNA binding|,10,-0.2,0.218,10,-0.2,1.15,-0.2,1.27,-1.27,0.477,0,0,-1.6,0.9
ENSMUSG00000006342,SUSD2,sushi domain containing 2,membrane|integral component of membrane|extracellular vesicular exosome|,immune response|biological_process|,molecular_function|scavenger receptor activity|polysaccharide binding|,10,-0.2,1.84,10,0.1,0.161,-0.2,1.27,-1.27,0.477,0,0,-1.4,1.1
ENSMUSG00000069727,GM5595,predicted gene 5595,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.5,1.04,10,-1.3,2.6,-1.2,1.26,-1.26,0.479,0,0,-2,0.3
ENSMUSG00000028952,ZBTB48,zinc finger and BTB domain containing 48,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.3,1.11,10,-0.4,2.6,0.2,1.25,1.25,0.48,0,0,-1.2,1.5
ENSMUSG00000025977,BOLL,"bol, boule-like (Drosophila)",cytoplasm|,regulation of translation|meiotic nuclear division|multicellular organismal development|spermatogenesis|cell differentiation|positive regulation of translational initiation|,nucleotide binding|nucleic acid binding|RNA binding|translation activator activity|,10,-0.3,0.98,10,-0.1,0.563,-0.2,1.24,-1.24,0.482,0,0,-1.4,1.1
ENSMUSG00000028644,ERMAP,erythroblast membrane-associated protein,cytoplasm|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,biological_process|,molecular_function|,10,-0.5,0.56,10,0.4,1.95,0.2,1.23,1.23,0.484,0,0,-1.5,1.3
ENSMUSG00000040712,CAMTA2,calmodulin binding transcription activator 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|cardiac muscle hypertrophy in response to stress|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|chromatin binding|transcription factor binding|histone deacetylase binding|,10,0.1,0.348,10,0.9,2.17,0.4,1.23,1.23,0.484,0,0,-0.2,1.9
ENSMUSG00000035934,PKNOX2,Pbx/knotted 1 homeobox 2,nucleus|cytoplasm|actin cytoskeleton|microtubule cytoskeleton|,"regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|",DNA binding|actin monomer binding|sequence-specific DNA binding|sequence-specific DNA binding|actin filament binding|,10,1,2.09,10,0.3,0.147,0.4,1.22,1.22,0.486,0,0,-0.2,2
ENSMUSG00000029832,NFE2L3,"nuclear factor, erythroid derived 2, like 3",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.1,0.373,10,-0.3,1.88,-0.2,1.22,-1.22,0.486,0,0,-1.3,1.3
ENSMUSG00000021500,DDX46,DEAD (Asp-Glu-Ala-Asp) box polypeptide 46,nucleus|nucleolus|,mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,10,-1,1.57,10,0.4,2.15,0.3,1.22,1.22,0.486,0,0,-2,1
ENSMUSG00000026398,NR5A2,"nuclear receptor subfamily 5, group A, member 2",nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|bile acid metabolic process|intracellular receptor signaling pathway|regulation of cell proliferation|cholesterol homeostasis|steroid hormone mediated signaling pathway|positive regulation of viral genome replication|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|phospholipid binding|zinc ion binding|lipid binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0.3,2.62,10,0,0,0.3,1.2,1.2,0.49,0,0,-1.4,1.4
ENSMUSG00000054715,ZSCAN22,zinc finger and SCAN domain containing 22,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|metal ion binding|,10,-0.2,0.748,10,-0.7,1.23,-0.3,1.19,-1.19,0.492,0,0,-1.7,1
ENSMUSG00000051235,GEN1,"Gen homolog 1, endonuclease (Drosophila)",nucleus|centrosome|extracellular vesicular exosome|,"double-strand break repair via homologous recombination|DNA catabolic process, endonucleolytic|DNA repair|cellular response to DNA damage stimulus|regulation of centrosome duplication|resolution of recombination intermediates|resolution of mitotic recombination intermediates|positive regulation of mitotic cell cycle spindle assembly checkpoint|",DNA binding|catalytic activity|nuclease activity|endonuclease activity|crossover junction endodeoxyribonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,1,2.83,10,0.1,0.0445,0.2,1.19,1.19,0.492,0,0,-0.7,2
ENSMUSG00000004864,MAPK13,mitogen-activated protein kinase 13,intracellular|,"MAPK cascade|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|response to stress|response to osmotic stress|cell cycle|phosphorylation|peptidyl-serine phosphorylation|positive regulation of interleukin-6 production|intracellular signal transduction|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.2,2.5,10,0.1,0.503,-0.2,1.18,-1.18,0.494,0,0,-1.1,1.5
ENSMUSG00000008496,POU2F2,"POU domain, class 2, transcription factor 2",cell|nucleus|nucleus|cytoplasm|,"mature B cell differentiation|immunoglobulin secretion involved in immune response|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|immunoglobulin secretion|cell maturation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein domain specific binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,0,0,10,-0.5,2.57,-0.4,1.18,-1.18,0.494,0,0,-1.9,0.4
ENSMUSG00000020042,BTBD11,BTB (POZ) domain containing 11,cellular_component|membrane|integral component of membrane|,SMAD protein signal transduction|,molecular_function|protein heterodimerization activity|,10,-0.9,1.44,10,-0.2,0.946,-0.1,1.18,-1.18,0.494,0,0,-2,0.4
ENSMUSG00000007415,GATAD1,GATA zinc finger domain containing 1,nucleus|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|zinc ion binding|sequence-specific DNA binding|metal ion binding|,9,-0.1,0.512,9,-0.2,0.84,-0.2,1.18,-1.18,0.494,0,0,-1.9,0.5
ENSMUSG00000043342,HOXD9,homeobox D9,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|single fertilization|skeletal muscle tissue development|adult locomotory behavior|anterior/posterior pattern specification|anterior/posterior pattern specification|proximal/distal pattern formation|proximal/distal pattern formation|regulation of gene expression|mammary gland development|embryonic forelimb morphogenesis|embryonic forelimb morphogenesis|forelimb morphogenesis|hindlimb morphogenesis|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|embryonic skeletal system development|embryonic skeletal system development|peripheral nervous system neuron development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.4,1.3,10,0.1,0.327,0.3,1.18,1.18,0.494,0,0,-0.7,1.7
ENSMUSG00000026317,CLN8,"ceroid-lipofuscinosis, neuronal 8",mitochondrion|endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|membrane|integral component of membrane|,age-dependent response to oxidative stress|phospholipid metabolic process|phospholipid metabolic process|ceramide metabolic process|mitochondrial membrane organization|lysosome organization|nervous system development|visual perception|adult walking behavior|cholesterol metabolic process|cell death|associative learning|adult locomotory behavior|regulation of cell size|spinal cord motor neuron differentiation|somatic motor neuron differentiation|social behavior|negative regulation of apoptotic process|cellular protein catabolic process|cellular macromolecule catabolic process|cellular protein metabolic process|photoreceptor cell maintenance|musculoskeletal movement|neuromuscular process controlling posture|neuromuscular process controlling balance|negative regulation of transferase activity|L-glutamate uptake involved in synaptic transmission|retina development in camera-type eye|neurofilament cytoskeleton organization|,None,10,-0.1,0.0877,10,-0.3,1.7,-0.3,1.17,-1.17,0.496,0,0,-1.8,0.9
ENSMUSG00000049232,TIGD2,tigger transposable element derived 2,cellular_component|nucleus|,biological_process|,molecular_function|nucleic acid binding|DNA binding|,10,-0.8,1.03,10,0.6,1.38,0.4,1.15,1.15,0.5,0,0,-1.8,1.2
ENSMUSG00000028833,NCDN,neurochondrin,cytoplasm|cytosol|membrane|dendrite|cell projection|neuron projection|neuronal cell body|,neuron projection development|bone resorption|regulation of neuronal synaptic plasticity|,protein binding|,10,0.2,2.09,10,-0.4,0.551,0.2,1.15,1.15,0.5,0,0,-1.5,1.2
ENSMUSG00000033222,TTF2,"transcription termination factor, RNA polymerase II",nucleus|spliceosomal complex|cytoplasm|,"transcription, DNA-templated|DNA-templated transcription, termination|regulation of transcription, DNA-templated|mRNA processing|biological_process|RNA splicing|",nucleotide binding|nucleic acid binding|DNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|zinc ion binding|hydrolase activity|,10,-0.2,0.95,10,0.8,1.09,-0.2,1.14,-1.14,0.502,0,0,-1,1.8
ENSMUSG00000021754,MAP3K1,mitogen-activated protein kinase kinase kinase 1,intracellular|cytoplasm|cytoskeleton|membrane|,MAPK cascade|activation of MAPKK activity|epithelial cell morphogenesis|protein phosphorylation|transforming growth factor beta receptor signaling pathway|JNK cascade|activation of JNKK activity|activation of JUN kinase activity|apoptotic mitochondrial changes|phosphorylation|protein ubiquitination|regulation of cell migration|positive regulation of actin filament polymerization|wound healing|camera-type eye development|eyelid development in camera-type eye|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|JUN kinase kinase kinase activity|MAP kinase kinase kinase activity|ubiquitin-protein transferase activity|protein binding|ATP binding|zinc ion binding|JUN kinase binding|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|mitogen-activated protein kinase kinase binding|sphingolipid binding|metal ion binding|mitogen-activated protein kinase binding|",9,-0.3,1.82,9,0.6,2.22,-0.2,1.13,-1.13,0.504,0,0,-1.2,1.7
ENSMUSG00000057000,NXF3,nuclear RNA export factor 3,intracellular|cell|nucleus|cytoplasm|cytoplasm|nuclear RNA export factor complex|,mRNA export from nucleus|poly(A)+ mRNA export from nucleus|,mRNA binding|protein binding|,10,-0.1,0.239,10,-0.2,1.22,-0.2,1.11,-1.11,0.508,0,0,-1.5,1.4
ENSMUSG00000030084,PLXNA1,plexin A1,intracellular|nucleus|cytoplasm|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|multicellular organismal development|regulation of smooth muscle cell migration|dichotomous subdivision of terminal units involved in salivary gland branching|semaphorin-plexin signaling pathway|,receptor activity|protein binding|semaphorin receptor activity|,10,0,0,10,-0.3,1.8,-0.3,1.11,-1.11,0.508,0,0,-1.3,1.5
ENSMUSG00000028751,PLA2G2E,"phospholipase A2, group IIE",cellular_component|extracellular region|,lipid metabolic process|phospholipid metabolic process|lipid catabolic process|,phospholipase A2 activity|calcium ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0.2,1.4,0.2,1.11,1.11,0.508,0,0,-0.8,1.7
ENSMUSG00000025967,EEF1B2,eukaryotic translation elongation factor 1 beta 2,eukaryotic translation elongation factor 1 complex|,translation|translational elongation|,translation elongation factor activity|protein binding|,10,0,0,10,0.3,2.05,0.3,1.11,1.11,0.508,0,0,-0.6,1.7
ENSMUSG00000090290,GM17296,"predicted gene, 17296",None,None,None,10,0.6,1.6,10,-0.2,0.149,0.3,1.1,1.1,0.51,0,0,-0.9,1.8
ENSMUSG00000004661,ARID3B,AT rich interactive domain 3B (BRIGHT-like),intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|,8,-0.6,2.35,8,-0.2,0.28,-0.3,1.1,-1.1,0.51,0,0,-1.9,0.8
ENSMUSG00000021685,OTP,orthopedia homolog (Drosophila),nucleus|,"positive regulation of neuroblast proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|forebrain neuron differentiation|hypothalamus cell differentiation|neurohypophysis development|cell differentiation|",DNA binding|sequence-specific DNA binding|,10,0.1,0.256,10,-1.2,4.47,-1.2,1.09,-1.09,0.513,0,0,-2,0.4
ENSMUSG00000021469,MSX2,msh homeobox 2,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|ossification|osteoblast differentiation|chondrocyte development|osteoblast development|outflow tract septum morphogenesis|outflow tract morphogenesis|epithelial to mesenchymal transition involved in endocardial cushion formation|endochondral bone growth|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|negative regulation of cell proliferation|anterior/posterior pattern specification|signal transduction involved in regulation of gene expression|embryonic limb morphogenesis|BMP signaling pathway|BMP signaling pathway|positive regulation of BMP signaling pathway|negative regulation of CREB transcription factor activity|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|wound healing, spreading of epidermal cells|embryonic nail plate morphogenesis|wound healing|odontogenesis|anagen|embryonic digit morphogenesis|regulation of apoptotic process|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of fat cell differentiation|negative regulation of keratinocyte differentiation|positive regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|stem cell differentiation|cartilage development|cartilage development|positive regulation of catagen|bone trabecula formation|bone morphogenesis|frontal suture morphogenesis|branching involved in mammary gland duct morphogenesis|mammary gland epithelium development|BMP signaling pathway involved in heart development|enamel mineralization|cellular response to growth factor stimulus|cellular response to estradiol stimulus|activation of meiosis|negative regulation of transcription regulatory region DNA binding|positive regulation of mesenchymal cell apoptotic process|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|transcription factor binding transcription factor activity|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|transcription cofactor activity|protein binding|transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0,0,10,0.6,3.78,0.6,1.09,1.09,0.513,0,0,-0.4,1.9
ENSMUSG00000031996,APLP2,amyloid beta (A4) precursor-like protein 2,nucleus|plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,suckling behavior|cellular copper ion homeostasis|regulation of epidermal growth factor-activated receptor activity|mating behavior|locomotory behavior|cholesterol metabolic process|embryo development|extracellular matrix organization|forebrain development|midbrain development|regulation of protein binding|neuromuscular process controlling balance|,DNA binding|protein binding|heparin binding|identical protein binding|transition metal ion binding|,10,0.2,1.7,10,0,0,0.2,1.09,1.09,0.513,0,0,-0.9,1.6
ENSMUSG00000015627,GATA5,GATA binding protein 5,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|intestinal epithelial cell differentiation|cellular response to BMP stimulus|",enhancer sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,-0.3,2.63,-0.2,1.07,-1.07,0.517,0,0,-1.7,0.7
ENSMUSG00000024312,WDR46,WD repeat domain 46,cellular_component|,biological_process|,poly(A) RNA binding|,10,-0.2,0.737,10,-0.3,0.735,-0.2,1.07,-1.07,0.517,0,0,-1.9,0.5
ENSMUSG00000040985,SUN3,Sad1 and UNC84 domain containing 3,membrane|integral component of membrane|SUN-KASH complex|,biological_process|,protein binding|,10,0.8,0.313,10,0.2,0.885,0.2,1.06,1.06,0.519,0,0,-0.7,1.9
ENSMUSG00000067916,GM13139,predicted gene 13139,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.574,10,-0.3,0.799,-0.2,1.06,-1.06,0.519,0,0,-1.5,1.3
ENSMUSG00000041975,METTL8,methyltransferase like 8,nucleus|cytoplasm|,skeletal muscle tissue development|metabolic process|histone acetylation|methylation|fat cell differentiation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|histone acetyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,1.35,10,-0.1,0.167,-0.1,1.06,-1.06,0.519,0,0,-1.4,1.2
ENSMUSG00000042606,HIRIP3,HIRA interacting protein 3,nucleus|,biological_process|,molecular_function|,10,-0.1,0.0668,10,0.3,2.06,0.2,1.03,1.03,0.526,0,0,-1,1.5
ENSMUSG00000033499,LARP4B,"La ribonucleoprotein domain family, member 4B",nucleolus|cytoplasm|cytosol|cytoplasmic stress granule|membrane|polysomal ribosome|,regulation of translation|positive regulation of translation|,nucleic acid binding|RNA binding|poly(A) RNA binding|,9,-0.4,1.82,9,0.2,0.952,0.3,1.03,1.03,0.526,0,0,-1.3,1.5
ENSMUSG00000033752,MND1,meiotic nuclear divisions 1 homolog (S. cerevisiae),nucleus|,DNA recombination|meiotic nuclear division|,DNA binding|protein binding|,10,-0.2,1.08,10,0.1,0.165,-0.2,1.02,-1.02,0.528,0,0,-1.4,1.3
ENSMUSG00000047412,ZBTB44,zinc finger and BTB domain containing 44,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-1,1.85,10,-0.1,0.282,-0.2,1.01,-1.01,0.53,0,0,-2,0.3
ENSMUSG00000028029,AIMP1,aminoacyl tRNA synthetase complex-interacting multifunctional protein 1,extracellular region|extracellular space|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|cell surface|membrane|aminoacyl-tRNA synthetase multienzyme complex|cytoplasmic vesicle|,angiogenesis|negative regulation of endothelial cell proliferation|carbohydrate metabolic process|glucose metabolic process|translation|apoptotic process|inflammatory response|cell adhesion|cell-cell signaling|leukocyte migration|leukocyte migration|,tRNA binding|RNA binding|cytokine activity|protein homodimerization activity|,10,-0.3,1.99,10,0,0,-0.2,1,-1,0.532,0,0,-1.2,1.5
ENSMUSG00000023018,SMARCD1,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1",nucleus|SWI/SNF complex|npBAF complex|nBAF complex|,nucleosome disassembly|chromatin remodeling|nervous system development|chromatin modification|chromatin-mediated maintenance of transcription|,protein binding|protein complex scaffold|,6,-0.9,2.28,6,0.3,0.801,0.3,0.996,0.996,0.533,0,0,-2,1.2
ENSMUSG00000028619,TCEANC2,transcription elongation factor A (SII) N-terminal and central domain containing 2,cellular_component|nucleus|,"transcription, DNA-templated|",molecular_function|DNA binding|,10,-0.5,0.855,10,1.3,3.31,0.1,0.989,0.989,0.534,0,0,-0.8,2
ENSMUSG00000067261,FOXD3,forkhead box D3,nuclear chromatin|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|trophectodermal cell differentiation|embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0.2,1.14,10,0.1,0.148,0.1,0.988,0.988,0.534,0,0,-0.7,1.9
ENSMUSG00000045598,ZFP553,zinc finger protein 553,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.2,1.4,10,-0.1,0.106,-0.2,0.981,-0.981,0.536,0,0,-1.8,0.9
ENSMUSG00000032398,SNAPC5,"small nuclear RNA activating complex, polypeptide 5",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase III promoter|biological_process|",molecular_function|sequence-specific DNA binding transcription factor activity|,7,0,0,7,-0.3,1.54,-0.2,0.973,-0.973,0.538,0,0,-1.9,1.1
ENSMUSG00000069045,DDX3Y,"DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked",nucleus|cytoplasm|membrane|,None,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|,10,0.3,1.35,10,0.1,0.101,0.2,0.972,0.972,0.538,0,0,-0.8,1.8
ENSMUSG00000038518,JARID2,"jumonji, AT rich interactive domain 2",intracellular|nucleus|nucleus|histone methyltransferase complex|ESC/E(Z) complex|ESC/E(Z) complex|,"negative regulation of transcription from RNA polymerase II promoter|liver development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|negative regulation of cell proliferation|chromatin modification|cell differentiation|negative regulation of histone methylation|regulation of cell proliferation|negative regulation of transcription, DNA-templated|spleen development|thymus development|stem cell differentiation|positive regulation of histone H3-K9 methylation|",DNA binding|DNA binding|chromatin binding|protein binding|,10,0.9,1,10,0.3,0.512,0.3,0.957,0.957,0.542,0,0,-0.7,1.9
ENSMUSG00000040128,PNRC1,proline-rich nuclear receptor coactivator 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.19,10,0.1,0.217,-0.2,0.957,-0.957,0.542,0,0,-1.7,0.9
ENSMUSG00000053111,FANK1,fibronectin type 3 and ankyrin repeat domains 1,nucleus|cytoplasm|,biological_process|,molecular_function|,10,-0.2,1.52,10,0.1,0.0658,-0.2,0.954,-0.954,0.542,0,0,-1.2,1.7
ENSMUSG00000042185,NFRKB,nuclear factor related to kappa B binding protein,nucleus|Ino80 complex|Ino80 complex|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|biological_process|",protease binding|DNA binding|,10,0.1,0.455,10,0.9,1.14,0.1,0.949,0.949,0.543,0,0,-0.4,2
ENSMUSG00000031312,ITGB1BP2,integrin beta 1 binding protein 2,Z disc|,None,integrin binding|calcium ion binding|protein binding|zinc ion binding|SH3 domain binding|metal ion binding|,10,-0.1,0.811,10,-0.1,0.218,-0.1,0.948,-0.948,0.544,0,0,-1.4,1.3
ENSMUSG00000043456,ZFP536,zinc finger protein 536,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of neuron differentiation|negative regulation of retinoic acid receptor signaling pathway|",nucleic acid binding|DNA binding|retinoic acid-responsive element binding|metal ion binding|,10,0.2,0.636,10,0.1,0.468,0.2,0.945,0.945,0.544,0,0,-1.3,1.5
ENSMUSG00000027428,RBBP9,retinoblastoma binding protein 9,nucleus|nucleolus|cytoplasm|extracellular vesicular exosome|,regulation of cell proliferation|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.2,0.197,10,-0.5,1.37,-0.3,0.945,-0.945,0.544,0,0,-1.6,0.9
ENSMUSG00000007216,ZFP775,zinc finger protein 775,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.3,1.36,10,-0.7,1.14,0.2,0.941,0.941,0.545,0,0,-1.9,0.9
ENSMUSG00000040694,APOBEC2,"apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2",None,mRNA processing|mRNA modification|DNA demethylation|,"catalytic activity|GTP cyclohydrolase activity|tRNA-specific adenosine deaminase activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines|N-cyclopropylmelamine deaminase activity|N-cyclopropylammeline deaminase activity|N-cyclopropylammelide alkylamino hydrolase activity|2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity|tRNA-specific adenosine-37 deaminase activity|archaeal-specific GTP cyclohydrolase activity|metal ion binding|tRNA-specific adenosine-34 deaminase activity|",9,0.2,0.704,9,-0.2,0.555,0.2,0.939,0.939,0.546,0,0,-1.7,1.1
ENSMUSG00000025612,BACH1,BTB and CNC homology 1,nucleus|nucleus|nucleus|cytosol|,"regulation of transcription involved in G1/S transition of mitotic cell cycle|regulation of transcription involved in G2/M transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter in response to hypoxia|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0.1,0.386,10,0.2,0.672,0.2,0.927,0.927,0.549,0,0,-1.1,1.6
ENSMUSG00000035420,FAM170A,"family with sequence similarity 170, member A",nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",DNA binding|metal ion binding|,10,-0.5,2.09,10,0.2,0.49,-0.4,0.925,-0.925,0.549,0,0,-1.6,0.9
ENSMUSG00000020668,KIF3C,kinesin family member 3C,intracellular|cell|cytoplasm|cytoskeleton|kinesin complex|microtubule|neuronal cell body|neuronal ribonucleoprotein granule|,microtubule-based movement|organelle transport along microtubule|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|,10,0.4,2.15,10,-0.2,1.04,-0.2,0.918,-0.918,0.551,0,0,-1.1,1.5
ENSMUSG00000009628,TEX15,testis expressed gene 15,cellular_component|,synapsis|synaptonemal complex assembly|male meiosis|spermatogenesis|fertilization|regulation of double-strand break repair via homologous recombination|male genitalia development|regulation of protein localization|protein localization to chromosome|homeostasis of number of cells within a tissue|,molecular_function|,10,0,0,10,0.4,2.28,0.2,0.903,0.903,0.554,0,0,-1.2,1.5
ENSMUSG00000028670,LYPLA2,lysophospholipase 2,cytoplasm|extracellular vesicular exosome|,lipid metabolic process|fatty acid metabolic process|,"CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0,0,10,0.3,1.56,0.2,0.891,0.891,0.557,0,0,-0.9,1.7
ENSMUSG00000074785,PLXNC1,plexin C1,intracellular|membrane|membrane|integral component of membrane|,signal transduction|multicellular organismal development|,receptor activity|,10,-0.1,0.207,10,-0.2,0.826,-0.2,0.885,-0.885,0.558,0,0,-1.8,0.8
ENSMUSG00000074676,FOXS1,forkhead box S1,nucleus|,"blood vessel development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of multicellular organism growth|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|neuromuscular process controlling balance|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.4,0.517,10,0.1,0.591,0.2,0.884,0.884,0.559,0,0,-1.1,1.5
ENSMUSG00000022951,RCAN1,regulator of calcineurin 1,intracellular|nucleus|cytoplasm|,response to ischemia|response to stress|response to stress|response to oxidative stress|short-term memory|calcium-mediated signaling|locomotion involved in locomotory behavior|calcineurin-NFAT signaling cascade|calcineurin-NFAT signaling cascade|regulation of phosphoprotein phosphatase activity|skeletal muscle fiber development|,protein binding|identical protein binding|,9,-0.1,0.128,9,0.6,1.81,0.6,0.88,0.88,0.56,0,0,-0.5,1.9
ENSMUSG00000039841,ZFP800,zinc finger protein 800,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.1,0.568,10,-0.2,0.575,-0.2,0.873,-0.873,0.561,0,0,-1.2,1.6
ENSMUSG00000054074,SKIDA1,SKI/DACH domain containing 1,cellular_component|nucleus|,biological_process|,molecular_function|,10,-0.2,0.443,10,-0.1,0.592,-0.1,0.865,-0.865,0.563,0,0,-1.8,0.7
ENSMUSG00000020076,DDX50,DEAD (Asp-Glu-Ala-Asp) box polypeptide 50,nucleus|nucleolus|plasma membrane|membrane|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,-0.9,0.852,10,-0.4,1.42,-0.4,0.862,-0.862,0.564,0,0,-2,0.5
ENSMUSG00000071235,VRTN,vertebrae development associated,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,2.09,-0.3,0.857,-0.857,0.565,0,0,-1.9,0.6
ENSMUSG00000040310,ALX4,aristaless-like homeobox 4,nucleus|nucleus|transcription factor complex|transcription factor complex|,"hair follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|pattern specification process|muscle organ development|post-embryonic development|anterior/posterior pattern specification|anterior/posterior pattern specification|limb morphogenesis|limb morphogenesis|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic digit morphogenesis|embryonic digit morphogenesis|regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|digestive tract development|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|skeletal system morphogenesis|palate development|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|protein heterodimerization activity|HMG box domain binding|,10,-0.1,0.272,10,-0.8,1.09,-0.7,0.856,-0.856,0.565,0,0,-2,0.3
ENSMUSG00000053985,ZFP14,zinc finger protein 14,intracellular|nucleus|,"regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.7,1.88,-0.3,0.856,-0.856,0.565,0,0,-1.8,1
ENSMUSG00000042487,LEO1,"Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)",nucleus|Cdc73/Paf1 complex|,"endodermal cell fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA polyadenylation|histone monoubiquitination|Wnt signaling pathway|stem cell maintenance|stem cell maintenance|positive regulation of mRNA 3'-end processing|positive regulation of transcription elongation from RNA polymerase II promoter|histone H2B ubiquitination|negative regulation of myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",protein binding|,10,-0.3,1.11,9,-0.1,0.14,-0.2,0.849,-0.849,0.567,0,0,-1.5,1.2
ENSMUSG00000034245,HDAC11,histone deacetylase 11,histone deacetylase complex|histone deacetylase complex|nucleus|nucleus|cytoplasm|plasma membrane|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|oligodendrocyte development|chromatin modification|histone deacetylation|histone deacetylation|",histone deacetylase activity|histone deacetylase activity|protein binding|transcription factor binding|hydrolase activity|histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K14 specific)|histone deacetylase activity (H3-K9 specific)|histone deacetylase activity (H4-K16 specific)|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|NAD-dependent histone deacetylase activity (H3-K18 specific)|,10,-0.3,1.07,10,-0.1,0.0568,-0.2,0.845,-0.845,0.568,0,0,-1.5,1.1
ENSMUSG00000039531,ZUFSP,zinc finger with UFM1-specific peptidase domain,None,biological_process|,metal ion binding|,10,0.4,0.821,10,-0.4,1.67,-0.3,0.835,-0.835,0.57,0,0,-1.8,0.9
ENSMUSG00000038932,TCFL5,transcription factor-like 5 (basic helix-loop-helix),male germ cell nucleus|nucleus|,"regulation of transcription, DNA-templated|",DNA binding|DNA binding|,10,-0.1,0.356,10,-0.2,0.56,-0.1,0.826,-0.826,0.573,0,0,-1.4,1.4
ENSMUSG00000055917,ZFP277,zinc finger protein 277,cellular_component|,cellular response to hydrogen peroxide|regulation of cellular senescence|,RNA polymerase II core promoter sequence-specific DNA binding|protein binding|,10,-0.1,0.659,10,0.2,1.3,-0.2,0.825,-0.825,0.573,0,0,-1.5,1.1
ENSMUSG00000062040,ZFP27,zinc finger protein 27,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.886,10,0.1,0.00301,0.1,0.822,0.822,0.574,0,0,-0.7,1.9
ENSMUSG00000095567,NOC2L,nucleolar complex associated 2 homolog (S. cerevisiae),nucleus|nucleus|nucleoplasm|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of B cell apoptotic process|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|chromatin assembly|nucleolus to nucleoplasm transport|cellular response to UV|negative regulation of histone acetylation|negative regulation of histone acetylation|negative regulation of intrinsic apoptotic signaling pathway|",p53 binding|chromatin binding|transcription corepressor activity|nucleosome binding|nucleosomal histone binding|histone binding|histone binding|poly(A) RNA binding|repressing transcription factor binding|,10,1,3.44,10,0,0,0.5,0.816,0.816,0.575,0,0,-0.5,2
ENSMUSG00000046185,ZFP84,zinc finger protein 84,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.258,10,-0.1,0.615,-0.1,0.802,-0.802,0.579,0,0,-0.8,1.9
ENSMUSG00000021415,4933417A18RIK,RIKEN cDNA 4933417A18 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.34,10,0,0,-0.1,0.798,-0.798,0.58,0,0,-1.9,0.7
ENSMUSG00000026333,GIN1,gypsy retrotransposon integrase 1,None,DNA integration|,nucleic acid binding|,10,0,0,10,0.7,1.7,-0.2,0.779,-0.779,0.585,0,0,-1.2,1.7
ENSMUSG00000053935,ATF7IP,activating transcription factor 7 interacting protein,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|ATP catabolic process|DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|regulation of RNA polymerase II transcriptional preinitiation complex assembly|",transcription corepressor activity|ATPase activity|,10,0.1,0.692,10,0.1,0.152,0.1,0.777,0.777,0.585,0,0,-1,1.8
ENSMUSG00000024472,DCP2,DCP2 decapping enzyme homolog (S. cerevisiae),cytoplasmic mRNA processing body|nucleus|cytoplasm|RISC complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|mRNA catabolic process|mRNA catabolic process|histone mRNA catabolic process|",RNA binding|hydrolase activity|manganese ion binding|metal ion binding|m7G(5')pppN diphosphatase activity|,10,0.1,0.21,10,0.9,1.4,0.1,0.772,0.772,0.586,0,0,-0.6,2
ENSMUSG00000069729,ARID1B,AT rich interactive domain 1B (SWI-like),nucleus|cytoplasm|SWI/SNF complex|nBAF complex|,chromatin remodeling|,molecular_function|,10,-0.1,0.122,10,-0.4,1.31,-0.1,0.764,-0.764,0.589,0,0,-1.8,0.8
ENSMUSG00000051251,NHLH1,nescient helix loop helix 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|protein dimerization activity|,10,-0.1,0.0702,10,-0.2,0.806,-0.2,0.757,-0.757,0.591,0,0,-1.6,1
ENSMUSG00000021661,ANKRA2,"ankyrin repeat, family A (RFXANK-like), 2",nucleus|cytoplasm|cytoplasm|cytosol|cytoskeleton|membrane|membrane|,None,protein binding|low-density lipoprotein particle binding|histone deacetylase binding|,10,0.2,0.92,10,0.1,0.231,0.2,0.752,0.752,0.592,0,0,-1.2,1.7
ENSMUSG00000022682,RRN3,RRN3 RNA polymerase I transcription factor homolog (yeast),nucleus|nucleolus|,"in utero embryonic development|transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase I promoter|nucleolus organization|cytoplasm organization|cell proliferation|ribosome biogenesis|positive regulation of transcription, DNA-templated|homeostasis of number of cells|negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator|regulation of DNA-templated transcription, initiation|",RNA polymerase binding|,9,-0.1,0.157,9,-0.2,0.706,-0.2,0.752,-0.752,0.592,0,0,-1.7,1.1
ENSMUSG00000047242,TAF9B,"TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|transcription factor TFIID complex|transcription factor TFTC complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|positive regulation of cell growth|negative regulation of apoptotic process|protein stabilization|",molecular_function|protein heterodimerization activity|,10,-0.1,0.556,10,0.3,1.38,0.3,0.742,0.742,0.595,0,0,-1.4,1.4
ENSMUSG00000021614,VCAN,versican,extracellular region|proteinaceous extracellular matrix|extracellular space|membrane|extracellular matrix|intracellular membrane-bounded organelle|,osteoblast differentiation|cell adhesion|heart development|glial cell migration|,calcium ion binding|hyaluronic acid binding|carbohydrate binding|,10,0.3,1.91,10,0,0,0.2,0.74,0.74,0.595,0,0,-0.8,1.7
ENSMUSG00000021575,AHRR,aryl-hydrocarbon receptor repressor,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|xenobiotic metabolic process|signal transduction|response to xenobiotic stimulus|positive regulation of protein sumoylation|negative regulation of transcription, DNA-templated|",DNA binding|signal transducer activity|protein dimerization activity|,10,-0.4,1.53,10,0,0,-0.2,0.738,-0.738,0.596,0,0,-1.8,0.8
ENSMUSG00000041703,ZIC5,zinc finger protein of the cerebellum 5,nucleus|,neural tube closure|multicellular organismal development|nervous system development|cell differentiation|forebrain development|,nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0.3,1.05,0.2,0.735,0.735,0.597,0,0,-0.7,1.8
ENSMUSG00000050368,HOXD10,homeobox D10,nucleus|,"skeletal system development|skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|single fertilization|skeletal muscle tissue development|adult locomotory behavior|anterior/posterior pattern specification|proximal/distal pattern formation|regulation of gene expression|spinal cord motor neuron cell fate specification|embryonic limb morphogenesis|forelimb morphogenesis|hindlimb morphogenesis|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|peripheral nervous system neuron development|neuromuscular process|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,9,0,0,10,1.2,3.76,1.1,0.732,0.732,0.597,0,0,-0.3,2
ENSMUSG00000050619,ZSCAN29,zinc finger SCAN domains 29,nucleus|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|,sequence-specific DNA binding RNA polymerase II transcription factor activity|metal ion binding|,10,-0.2,0.96,10,-0.1,0.04,-0.2,0.725,-0.725,0.599,0,0,-1.5,1.1
ENSMUSG00000087598,ZFP111,zinc finger protein 111,cellular_component|,"regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.2,1.01,-0.1,0.713,-0.713,0.603,0,0,-1.7,0.9
ENSMUSG00000030123,PLXND1,plexin D1,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|lamellipodium|,angiogenesis|patterning of blood vessels|outflow tract morphogenesis|signal transduction|multicellular organismal development|synapse assembly|regulation of cell migration|positive regulation of protein binding|endothelial cell migration|regulation of angiogenesis|dichotomous subdivision of terminal units involved in salivary gland branching|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|,receptor activity|protein binding|semaphorin receptor activity|semaphorin receptor activity|protein domain specific binding|,10,0.9,2.92,10,-0.4,0.669,-0.4,0.708,-0.708,0.604,0,0,-1,2
ENSMUSG00000063065,MAPK3,mitogen-activated protein kinase 3,nucleus|nucleus|nucleus|nucleoplasm|cytoplasm|mitochondrion|early endosome|late endosome|Golgi apparatus|cytosol|cytosol|cytosol|cytoskeleton|caveola|focal adhesion|microtubule cytoskeleton|pseudopodium|protein complex|extracellular vesicular exosome|,"MAPK cascade|MAPK cascade|MAPK import into nucleus|positive regulation of protein phosphorylation|transcription, DNA-templated|protein complex assembly|protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|cellular response to DNA damage stimulus|DNA damage induced protein phosphorylation|cell cycle|signal transduction|response to toxic substance|organ morphogenesis|phosphorylation|phosphorylation|peptidyl-serine phosphorylation|sensory perception of pain|BMP signaling pathway|lipopolysaccharide-mediated signaling pathway|response to lipopolysaccharide|regulation of stress-activated MAPK cascade|positive regulation of histone phosphorylation|positive regulation of histone acetylation|intracellular signal transduction|peptidyl-tyrosine autophosphorylation|response to exogenous dsRNA|positive regulation of translation|positive regulation of transcription from RNA polymerase II promoter|regulation of sequence-specific DNA binding transcription factor activity|cartilage development|regulation of cytoskeleton organization|positive regulation of ERK1 and ERK2 cascade|interleukin-1-mediated signaling pathway|response to epidermal growth factor|caveolin-mediated endocytosis|regulation of Golgi inheritance|regulation of early endosome to late endosome transport|negative regulation of apolipoprotein binding|","nucleotide binding|phosphotyrosine binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|MAP kinase activity|MAP kinase activity|MAP kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|phosphatase binding|",10,-0.2,0.609,10,-0.1,0.209,-0.1,0.702,-0.702,0.605,0,0,-1.5,1.2
ENSMUSG00000038292,CCDC155,coiled-coil domain containing 155,"chromosome, telomeric region|lateral element|cell|nucleus|nuclear outer membrane|chromosome|membrane|integral component of membrane|",double-strand break repair via homologous recombination|synapsis|spermatogenesis|oogenesis|microtubule cytoskeleton organization involved in synapsis|chromosome localization to nuclear envelope involved in synapsis|,protein binding|identical protein binding|dynein complex binding|,10,0.1,0.272,10,0.3,0.788,0.2,0.691,0.691,0.609,0,0,-0.9,1.7
ENSMUSG00000044835,ANKRD45,ankyrin repeat domain 45,cellular_component|,biological_process|,molecular_function|,10,0.3,1.24,10,0.1,0.0308,0.2,0.688,0.688,0.609,0,0,-0.9,1.7
ENSMUSG00000012076,BRMS1L,breast cancer metastasis-suppressor 1-like,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|regulation of growth|",molecular_function|,10,0.1,0.307,10,0.1,0.44,0.1,0.684,0.684,0.61,0,0,-1.4,1.4
ENSMUSG00000057101,ZFP180,zinc finger protein 180,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.855,10,0,0,-0.1,0.684,-0.684,0.61,0,0,-1.5,1.3
ENSMUSG00000074151,NLRC5,"NLR family, CARD domain containing 5",nucleus|nucleus|cytoplasm|cytosol|cytosol|,immune system process|defense response|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB transcription factor activity|regulation of kinase activity|innate immune response|innate immune response|positive regulation of MHC class I biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of interferon-gamma-mediated signaling pathway|negative regulation of type I interferon-mediated signaling pathway|negative regulation of type I interferon-mediated signaling pathway|positive regulation of type I interferon-mediated signaling pathway|,nucleotide binding|RNA polymerase II core promoter sequence-specific DNA binding|ATP binding|,10,0.1,0.51,9,0.3,0.409,0.1,0.666,0.666,0.616,0,0,-1.4,1.4
ENSMUSG00000038954,SUPT3,suppressor of Ty 3,nucleus|cytoplasm|STAGA complex|transcription factor TFTC complex|,histone deubiquitination|histone H3 acetylation|regulation of RNA biosynthetic process|,transcription coactivator activity|histone acetyltransferase activity|,9,0.1,0.165,9,-0.2,1.9,-0.2,0.664,-0.664,0.616,0,0,-1.7,1.2
ENSMUSG00000030866,ERN2,endoplasmic reticulum (ER) to nucleus signalling 2,intracellular|endoplasmic reticulum|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|protein phosphorylation|apoptotic process|response to unfolded protein|cell cycle arrest|metabolic process|rRNA catabolic process|phosphorylation|apoptotic chromosome condensation|response to endoplasmic reticulum stress|negative regulation of transcription, DNA-templated|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|nucleic acid phosphodiester bond hydrolysis|","nucleotide binding|magnesium ion binding|catalytic activity|endonuclease activity|ribonuclease activity|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|bidentate ribonuclease III activity|transferase activity|transferase activity, transferring phosphorus-containing groups|hydrolase activity|metal ion binding|",10,0.1,0.0812,10,0.2,0.667,0.1,0.652,0.652,0.619,0,0,-0.7,1.8
ENSMUSG00000049871,NLRC3,"NLR family, CARD domain containing 3",cytoplasm|cytoplasm|,I-kappaB kinase/NF-kappaB signaling|I-kappaB kinase/NF-kappaB signaling|regulation of protein ubiquitination|regulation of protein ubiquitination|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB transcription factor activity|response to lipopolysaccharide|T cell activation|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of I-kappaB kinase/NF-kappaB signaling|,nucleotide binding|protein binding|ATP binding|,10,0.2,0.196,10,0.2,0.514,0.2,0.65,0.65,0.62,0,0,-0.8,1.8
ENSMUSG00000052763,ZFP212,Zinc finger protein 212,cellular_component|,biological_process|,identical protein binding|metal ion binding|,10,0.1,0.152,10,0.2,0.856,0.1,0.647,0.647,0.621,0,0,-0.9,1.8
ENSMUSG00000006941,EIF1B,eukaryotic translation initiation factor 1B,cellular_component|,translation|translational initiation|biological_process|,translation initiation factor activity|poly(A) RNA binding|,10,0,0,10,-0.2,1.04,-0.2,0.646,-0.646,0.621,0,0,-1.8,0.8
ENSMUSG00000029771,IRF5,interferon regulatory factor 5,nucleus|cytoplasm|,"immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|response to peptidoglycan|response to muramyl dipeptide|positive regulation of apoptotic process|innate immune response|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|",regulatory region DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.1,0.0446,10,-0.2,0.715,-0.1,0.643,-0.643,0.622,0,0,-1.7,1.1
ENSMUSG00000038533,CBFA2T2,"core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)",nucleus|,"regulation of transcription, DNA-templated|positive regulation of neuron projection development|epithelial cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of RNA biosynthetic process|",sequence-specific DNA binding transcription factor activity|transcription corepressor activity|transcription corepressor activity|protein binding|metal ion binding|,10,0.4,0.778,10,0.2,0.419,0.3,0.638,0.638,0.624,0,0,-0.9,1.7
ENSMUSG00000025478,DPYSL4,dihydropyrimidinase-like 4,cytoplasm|,pyrimidine nucleobase catabolic process|,"protein binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|phosphoprotein binding|",9,0.1,0.159,9,0.2,0.668,0.1,0.638,0.638,0.624,0,0,-0.9,1.9
ENSMUSG00000054360,BSX,brain specific homeobox,nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|locomotory behavior|eating behavior|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|mammary gland involution|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0.2,0.364,10,0.2,0.332,0.2,0.637,0.637,0.624,0,0,-1.1,1.6
ENSMUSG00000009585,APOBEC3,"apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3",nucleus|cytoplasm|,hematopoietic progenitor cell differentiation|immune system process|metabolic process|negative regulation of transposition|negative regulation of transposition|negative regulation of viral genome replication|innate immune response|defense response to virus|,"catalytic activity|GTP cyclohydrolase activity|protein binding|tRNA-specific adenosine deaminase activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines|N-cyclopropylmelamine deaminase activity|N-cyclopropylammeline deaminase activity|N-cyclopropylammelide alkylamino hydrolase activity|2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity|tRNA-specific adenosine-37 deaminase activity|archaeal-specific GTP cyclohydrolase activity|poly(A) RNA binding|metal ion binding|deoxycytidine deaminase activity|tRNA-specific adenosine-34 deaminase activity|",10,0.1,0.215,10,0.2,0.55,0.2,0.634,0.634,0.625,0,0,-1.1,1.6
ENSMUSG00000033740,ST18,suppression of tumorigenicity 18,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding|metal ion binding|,10,-0.2,1.04,10,0.4,1.83,-0.2,0.633,-0.633,0.625,0,0,-1.2,1.4
ENSMUSG00000049037,CLEC4A1,"C-type lectin domain family 4, member a1",cellular_component|,biological_process|,molecular_function|,10,-0.8,0.0584,10,-0.3,0.976,-0.2,0.632,-0.632,0.626,0,0,-1.9,0.7
ENSMUSG00000052751,REPIN1,replication initiator 1,nucleus|lipid particle|cytosol|cytosolic ribosome|nuclear membrane|,DNA replication|regulation of fatty acid transport|regulation of glucose import in response to insulin stimulus|,nucleic acid binding|DNA binding|poly(A) RNA binding|metal ion binding|,10,0.1,0.676,10,0.1,0.00852,0.1,0.631,0.631,0.626,0,0,-0.8,2
ENSMUSG00000037447,ARID5A,AT rich interactive domain 5A (MRF1-like),intracellular|nucleus|nucleus|transcription factor complex|nucleolus|,"chondrocyte differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of histone acetylation|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|chromatin binding|transcription factor binding|,10,0,0,10,0.3,1.82,0.2,0.625,0.625,0.628,0,0,-1.1,1.6
ENSMUSG00000032495,LRRC2,leucine rich repeat containing 2,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.56,10,0,0,0.1,0.623,0.623,0.628,0,0,-1.1,1.7
ENSMUSG00000043683,FEM1A,feminization 1 homolog a (C. elegans),cellular_component|cytoplasm|,negative regulation of MAP kinase activity|negative regulation of inflammatory response|negative regulation of inflammatory response|,transcription factor binding|EP4 subtype prostaglandin E2 receptor binding|,10,-0.2,1.19,10,0,0,-0.2,0.617,-0.617,0.63,0,0,-1.6,1.2
ENSMUSG00000048450,MSX1,msh homeobox 1,nucleus|nucleus|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|in utero embryonic development|epithelial to mesenchymal transition|heart morphogenesis|epithelial to mesenchymal transition involved in endocardial cushion formation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|heart development|muscle organ development|negative regulation of cell proliferation|anterior/posterior pattern specification|mesenchymal cell proliferation|signal transduction involved in regulation of gene expression|negative regulation of cell growth|embryonic limb morphogenesis|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|positive regulation of BMP signaling pathway|forebrain development|midbrain development|protein localization to nucleus|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic nail plate morphogenesis|embryonic nail plate morphogenesis|embryonic nail plate morphogenesis|middle ear morphogenesis|odontogenesis of dentin-containing tooth|odontogenesis of dentin-containing tooth|odontogenesis|odontogenesis|regulation of odontogenesis|embryonic digit morphogenesis|negative regulation of apoptotic process|negative regulation of DNA binding|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|stem cell differentiation|protein stabilization|negative regulation of striated muscle cell differentiation|negative regulation of striated muscle cell differentiation|cartilage development|palate development|face morphogenesis|face morphogenesis|face morphogenesis|bone morphogenesis|bone morphogenesis|cartilage morphogenesis|mammary gland epithelium development|BMP signaling pathway involved in heart development|activation of meiosis|positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator|negative regulation of transcription regulatory region DNA binding|positive regulation of mesenchymal cell apoptotic process|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|p53 binding|DNA binding|protein binding|sequence-specific DNA binding|,10,0.1,0.179,10,0.6,1.06,0.2,0.613,0.613,0.631,0,0,-0.5,1.9
ENSMUSG00000022441,EFCAB6,EF-hand calcium binding domain 6,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",calcium ion binding|metal ion binding|,10,0.2,0.544,10,-0.8,2.68,-0.5,0.605,-0.605,0.634,0,0,-1.9,0.9
ENSMUSG00000032368,ZIC1,zinc finger protein of the cerebellum 1,nucleus|nucleus|cytoplasm|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|nervous system development|central nervous system development|central nervous system development|brain development|brain development|adult walking behavior|regulation of smoothened signaling pathway|spinal cord development|cell differentiation|positive regulation of protein import into nucleus|positive regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,0.2,1.01,10,-0.3,1.79,-0.2,0.605,-0.605,0.634,0,0,-1.8,0.9
ENSMUSG00000021010,NPAS3,neuronal PAS domain protein 3,nucleus|nucleus|cytoplasm|,"startle response|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|locomotory behavior|maternal behavior|positive regulation of transcription, DNA-templated|",DNA binding|signal transducer activity|protein binding|protein dimerization activity|,10,0.3,0.523,10,0.1,0.442,0.2,0.601,0.601,0.635,0,0,-1.1,1.6
ENSMUSG00000002658,GTF2F1,"general transcription factor IIF, polypeptide 1",nucleus|cell junction|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|positive regulation of transcription elongation from RNA polymerase II promoter|positive regulation of catalytic activity|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|catalytic activity|protein binding|transcription factor binding|phosphatase activator activity|poly(A) RNA binding|,10,0.2,0.15,10,-0.2,0.962,0.2,0.594,0.594,0.637,0,0,-1,1.7
ENSMUSG00000069189,ZDHHC11,"zinc finger, DHHC domain containing 11",endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,"molecular_function|zinc ion binding|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.2,0.172,10,-0.2,0.48,-0.2,0.588,-0.588,0.639,0,0,-1.7,1
ENSMUSG00000010476,EBF3,early B cell factor 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of transcription, DNA-templated|",DNA binding|protein binding|metal ion binding|protein dimerization activity|,10,0,0,10,0.2,0.692,0.2,0.588,0.588,0.639,0,0,-1,1.7
ENSMUSG00000025821,ZFP282,zinc finger protein 282,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.3,1.33,10,0,0,0.1,0.576,0.576,0.642,0,0,-0.9,1.7
ENSMUSG00000029840,MTPN,myotrophin,nucleus|cytoplasm|cytosol|F-actin capping protein complex|axon|extracellular vesicular exosome|,positive regulation of macromolecule biosynthetic process|positive regulation of cardiac muscle hypertrophy|cell growth|positive regulation of cell growth|positive regulation of NF-kappaB transcription factor activity|positive regulation of protein metabolic process|regulation of barbed-end actin filament capping|,None,10,-0.2,0.631,10,0.1,0.611,0.1,0.573,0.573,0.643,0,0,-1,1.7
ENSMUSG00000023165,SSXB2,"synovial sarcoma, X member B, breakpoint 2",cellular_component|,biological_process|,molecular_function|,4,-0.2,0.39,4,-0.2,0.234,-0.2,0.571,-0.571,0.644,0,0,-2,1.3
ENSMUSG00000021271,ZFP839,zinc finger protein 839,cellular_component|,biological_process|,molecular_function|,9,-0.4,0.792,10,-0.2,0.135,-0.4,0.571,-0.571,0.644,0,0,-1.7,0.9
ENSMUSG00000034673,PBX2,pre B cell leukemia homeobox 2,nucleus|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|proximal/distal pattern formation|embryonic limb morphogenesis|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|,10,0,0,10,0.1,0.731,0.1,0.563,0.563,0.646,0,0,-1.1,1.7
ENSMUSG00000025085,ABLIM1,actin-binding LIM protein 1,stress fiber|cytoplasm|cytoskeleton|actin cytoskeleton|lamellipodium|,cytoskeleton organization|axon guidance|lamellipodium assembly|cilium assembly|positive regulation of transcription from RNA polymerase II promoter|,actin binding|protein binding|zinc ion binding|metal ion binding|,10,-0.3,0.299,10,-0.7,0.836,-0.4,0.56,-0.56,0.647,0,0,-2,0.5
ENSMUSG00000020228,HELB,helicase (DNA) B,alpha DNA polymerase:primase complex|,"ATP catabolic process|DNA replication|DNA-dependent DNA replication|DNA replication, synthesis of RNA primer|DNA replication, synthesis of RNA primer|DNA duplex unwinding|DNA duplex unwinding|",nucleotide binding|ATP-dependent DNA helicase activity|helicase activity|ATP binding|hydrolase activity|single-stranded DNA-dependent ATP-dependent DNA helicase activity|ATP-dependent 5'-3' DNA helicase activity|,10,-0.7,2.67,10,0,0,-0.2,0.559,-0.559,0.648,0,0,-2,0.4
ENSMUSG00000032329,HMG20A,high mobility group 20A,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|negative regulation of neuron differentiation|negative regulation of neuron differentiation|",DNA binding|protein heterodimerization activity|,10,0,0,10,0.2,1.6,0.1,0.549,0.549,0.651,0,0,-1.2,1.6
ENSMUSG00000030386,ZFP606,zinc finger protein 606,nucleus|cytoplasm|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.2,0.937,-0.1,0.546,-0.546,0.652,0,0,-1.7,1.1
ENSMUSG00000038773,KDM3B,KDM3B lysine (K)-specific demethylase 3B,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|chromatin modification|oxidation-reduction process|","sulfonate dioxygenase activity|molecular_function|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.4,0.553,10,-0.2,0.459,-0.4,0.546,-0.546,0.652,0,0,-1.6,1.2
ENSMUSG00000066760,PSG16,pregnancy specific glycoprotein 16,None,female pregnancy|,None,10,-0.2,0.626,10,-0.1,0.0447,-0.1,0.536,-0.536,0.655,0,0,-1.6,1.2
ENSMUSG00000034653,YTHDC2,YTH domain containing 2,endoplasmic reticulum|endoplasmic reticulum|,ATP catabolic process|response to tumor necrosis factor|positive regulation by host of viral genome replication|response to interleukin-1|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|RNA-dependent ATPase activity|hydrolase activity|poly(A) RNA binding|RNA polymerase binding|,10,-0.1,0.329,10,-0.1,0.255,-0.1,0.534,-0.534,0.655,0,0,-1.3,1.7
ENSMUSG00000038618,RASSF7,Ras association (RalGDS/AF-6) domain family (N-terminal) member 7,cellular_component|cytoplasm|cytoskeleton|,apoptotic process|signal transduction|biological_process|,molecular_function|,10,-0.2,0.48,10,-0.9,1.57,-0.4,0.532,-0.532,0.656,0,0,-2,0.3
ENSMUSG00000035365,PARPBP,PARP1 binding protein,chromatin|nucleus|cytoplasm|,DNA repair|cellular response to DNA damage stimulus|negative regulation of double-strand break repair via homologous recombination|,molecular_function|DNA binding|,10,0,0,10,-0.4,0.804,-0.1,0.529,-0.529,0.657,0,0,-1.9,0.7
ENSMUSG00000045662,HENMT1,HEN1 methyltransferase homolog 1 (Arabidopsis),cellular_component|cytoplasm|,RNA methylation|gene silencing by RNA|methylation|piRNA metabolic process|,RNA binding|methyltransferase activity|O-methyltransferase activity|RNA methyltransferase activity|transferase activity|metal ion binding|,10,-0.9,1.11,10,0.2,0.375,-0.1,0.523,-0.523,0.659,0,0,-2,0.7
ENSMUSG00000031728,ZFP821,zinc finger protein 821,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.1,0.164,10,0.6,1.11,0.4,0.523,0.523,0.659,0,0,-0.6,1.9
ENSMUSG00000029706,PAX4,paired box 4,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|organ morphogenesis|cell differentiation|negative regulation of apoptotic process|regulation of cell differentiation|positive regulation of cell differentiation|negative regulation of transcription, DNA-templated|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.1,0.136,10,-0.3,0.569,-0.1,0.523,-0.523,0.659,0,0,-1.4,1.3
ENSMUSG00000055298,CTSJ,cathepsin J,lysosome|perinuclear region of cytoplasm|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.3,0.632,10,-0.4,2.25,-0.3,0.522,-0.522,0.659,0,0,-1.8,0.9
ENSMUSG00000050328,HOXC12,homeobox C12,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|biological_process|",molecular_function|DNA binding|sequence-specific DNA binding|,10,0.4,2.64,10,-0.1,0.132,0.4,0.521,0.521,0.659,0,0,-0.7,1.8
ENSMUSG00000031881,CDH16,cadherin 16,plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,cell adhesion|homophilic cell adhesion|calcium-dependent cell-cell adhesion|calcium-dependent cell-cell adhesion|,calcium ion binding|metal ion binding|,10,1,2.88,10,0.1,0.144,0.4,0.519,0.519,0.66,0,0,-0.5,2
ENSMUSG00000058093,AA987161,expressed sequence AA987161,None,biological_process|,molecular_function|metal ion binding|,10,-0.2,0.144,10,0.2,0.822,0.1,0.516,0.516,0.661,0,0,-1.3,1.5
ENSMUSG00000071477,ZFP777,zinc finger protein 777,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.2,0.607,10,-0.3,1.53,-0.2,0.515,-0.515,0.661,0,0,-1.3,1.4
ENSMUSG00000001910,NACC1,"nucleus accumbens associated 1, BEN and BTB (POZ) domain containing",nucleus|cytoplasm|nuclear body|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|negative regulation of transcription, DNA-templated|protein homooligomerization|",protein binding|,10,0,0,10,-0.2,1.18,-0.1,0.511,-0.511,0.663,0,0,-1.7,1
ENSMUSG00000055612,CDCA7,cell division cycle associated 7,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|regulation of cell proliferation|",molecular_function|,10,-0.3,1.17,10,0.1,0.478,0.1,0.51,0.51,0.663,0,0,-1.3,1.4
ENSMUSG00000023106,DENR,density-regulated protein,cellular_component|,formation of translation preinitiation complex|IRES-dependent translational initiation|translational initiation|ribosome disassembly|,molecular_function|translation initiation factor activity|,9,1,2.59,9,-0.3,1.28,-0.2,0.509,-0.509,0.663,0,0,-1,2
ENSMUSG00000051557,PUSL1,pseudouridylate synthase-like 1,None,pseudouridine synthesis|tRNA processing|RNA modification|,RNA binding|pseudouridine synthase activity|isomerase activity|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|baruol synthase activity|,10,-0.1,0.351,10,-0.1,0.204,-0.1,0.508,-0.508,0.664,0,0,-1.7,1
ENSMUSG00000026305,LRRFIP1,leucine rich repeat (in FLII) interacting protein 1,nucleus|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|protein binding|protein homodimerization activity|,10,0.1,0.0442,10,-0.4,1.27,-0.2,0.508,-0.508,0.664,0,0,-1.5,1.5
ENSMUSG00000027803,WWTR1,WW domain containing transcription regulator 1,nucleus|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|osteoblast differentiation|osteoblast differentiation|negative regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of protein kinase activity|positive regulation of cell proliferation|positive regulation of epithelial to mesenchymal transition|stem cell division|glomerulus development|hippo signaling|negative regulation of catenin import into nucleus|negative regulation of fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cilium morphogenesis|regulation of SMAD protein import into nucleus|regulation of canonical Wnt signaling pathway|regulation of metanephric nephron tubule epithelial cell differentiation|negative regulation of canonical Wnt signaling pathway|regulation of RNA biosynthetic process|",transcription coactivator activity|transcription coactivator activity|transcription corepressor activity|protein binding|protein homodimerization activity|,10,-0.2,1.04,10,0,0,-0.1,0.501,-0.501,0.666,0,0,-1.6,1.2
ENSMUSG00000045034,ANKRD34B,ankyrin repeat domain 34B,cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.6,1.38,10,0,0,0.2,0.501,0.501,0.666,0,0,-0.8,1.9
ENSMUSG00000037896,RCOR1,REST corepressor 1,nucleus|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|chromatin modification|erythrocyte differentiation|positive regulation of megakaryocyte differentiation|negative regulation of transcription, DNA-templated|histone H4 deacetylation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|protein binding|transcription regulatory region DNA binding|,10,-0.2,0.274,10,-0.1,0.302,-0.2,0.497,-0.497,0.667,0,0,-1.5,1.7
ENSMUSG00000029844,HOXA1,homeobox A1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|sensory perception of sound|optokinetic behavior|motor neuron axon guidance|anatomical structure morphogenesis|anatomical structure morphogenesis|anterior/posterior pattern specification|anterior/posterior pattern specification|rhombomere 3 development|rhombomere 3 development|rhombomere 4 development|rhombomere 4 development|rhombomere 5 development|rhombomere 5 development|abducens nerve formation|facial nerve structural organization|facial nucleus development|central nervous system neuron differentiation|hindbrain development|inner ear morphogenesis|outer ear morphogenesis|positive regulation of transcription from RNA polymerase II promoter|anatomical structure formation involved in morphogenesis|embryonic neurocranium morphogenesis|inner ear development|artery morphogenesis|regulation of behavior|cognition|neuromuscular process|artery development|semicircular canal formation|cochlea development|cochlea morphogenesis|",DNA binding|protein binding|sequence-specific DNA binding|,10,0.3,1.12,10,-0.1,0.226,0.1,0.494,0.494,0.668,0,0,-1.2,1.6
ENSMUSG00000042156,DZIP1,DAZ interacting protein 1,nucleus|cytoplasm|centriole|ciliary basal body|,multicellular organismal development|spermatogenesis|cell differentiation|cilium assembly|,protein binding|metal ion binding|,10,0,0,10,-0.2,1.19,-0.1,0.494,-0.494,0.668,0,0,-1.6,1.1
ENSMUSG00000038535,ZFP280D,zinc finger protein 280D,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,9,0.2,0.634,9,0.1,0.0321,0.1,0.48,0.48,0.673,0,0,-1.4,1.6
ENSMUSG00000035027,MAP2K2,mitogen-activated protein kinase kinase 2,nucleus|cytoplasm|cytoplasm|mitochondrion|early endosome|late endosome|peroxisomal membrane|endoplasmic reticulum|Golgi apparatus|Golgi apparatus|cytosol|cytosol|microtubule|cell-cell junction|focal adhesion|cell cortex|cytoplasmic side of plasma membrane|perinuclear region of cytoplasm|,MAPK cascade|activation of MAPK activity|activation of MAPK activity|protein phosphorylation|protein phosphorylation|phosphorylation|regulation of stress-activated MAPK cascade|peptidyl-serine autophosphorylation|positive regulation of protein serine/threonine kinase activity|regulation of Golgi inheritance|positive regulation of cell motility|regulation of early endosome to late endosome transport|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|PDZ domain binding|protein complex scaffold|protein serine/threonine kinase activator activity|scaffold protein binding|",10,0,0,10,-0.2,0.875,-0.1,0.474,-0.474,0.676,0,0,-1.5,1.3
ENSMUSG00000063108,ZFP26,zinc finger protein 26,intracellular|nucleus|,"regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,9,-0.1,0.412,9,-0.2,0.12,-0.1,0.471,-0.471,0.677,0,0,-1.8,1.1
ENSMUSG00000092558,MED20,mediator complex subunit 20,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|skeletal muscle cell differentiation|",RNA polymerase II transcription cofactor activity|protein binding|,2,0.6,1.46,2,0,0,0.6,0.467,0.467,0.678,0,0,-1.6,2
ENSMUSG00000022811,ZFP148,zinc finger protein 148,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|protein complex assembly|gamete generation|negative regulation of gene expression|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",transcription regulatory region sequence-specific DNA binding|nucleic acid binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|metal ion binding|,10,0.2,1.22,10,-0.1,0.423,-0.1,0.465,-0.465,0.679,0,0,-1.4,1.3
ENSMUSG00000067071,HES6,hairy and enhancer of split 6,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription cofactor activity|transcription factor binding|protein dimerization activity|,10,0.3,2.02,10,-0.2,0.667,0.2,0.458,0.458,0.681,0,0,-1.1,1.5
ENSMUSG00000034544,RSRC1,arginine/serine-rich coiled-coil 1,nucleus|cytoplasm|nuclear speck|,"alternative mRNA splicing, via spliceosome|mRNA splicing, via spliceosome|mRNA processing|protein phosphorylation|nucleocytoplasmic transport|RNA splicing|response to antibiotic|",protein binding|,10,-0.2,0.82,10,0,0,-0.1,0.457,-0.457,0.681,0,0,-1.5,1.3
ENSMUSG00000070420,ZSCAN25,zinc finger and SCAN domain containing 25,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|metal ion binding|,10,-0.1,0.0437,10,-0.1,0.448,-0.1,0.451,-0.451,0.683,0,0,-1.5,1.3
ENSMUSG00000040433,ZBTB38,zinc finger and BTB domain containing 38,nucleus|blood microparticle|,"negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",sequence-specific DNA binding transcription factor activity|methyl-CpG binding|protein homodimerization activity|metal ion binding|,9,0,0,10,-0.3,1.31,-0.2,0.448,-0.448,0.684,0,0,-1.8,0.9
ENSMUSG00000057895,ZFP105,zinc finger protein 105,nucleus|perinuclear region of cytoplasm|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.1,0.679,10,0.2,0.266,-0.1,0.437,-0.437,0.688,0,0,-1.7,1.1
ENSMUSG00000028389,ZFP37,zinc finger protein 37,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|germ cell development|spermatogenesis|cell differentiation|",nucleic acid binding|DNA binding|zinc ion binding|metal ion binding|,10,-0.1,0.217,10,-0.1,0.258,-0.1,0.434,-0.434,0.689,0,0,-1.6,1.2
ENSMUSG00000029814,IGF2BP3,insulin-like growth factor 2 mRNA binding protein 3,nucleus|cytoplasm|,regulation of translation|transport|mRNA transport|,nucleotide binding|nucleic acid binding|RNA binding|mRNA 3'-UTR binding|poly(A) RNA binding|mRNA 5'-UTR binding|,10,0.1,0.0491,10,0.1,0.424,0.1,0.433,0.433,0.689,0,0,-1.6,1.4
ENSMUSG00000097918,ASCL5,achaete-scute complex homolog 5 (Drosophila),cellular_component|,biological_process|,molecular_function|,10,0.2,0.961,10,-0.9,2.18,0.1,0.428,0.428,0.691,0,0,-2,0.7
ENSMUSG00000059842,ZFP341,zinc finger protein 341,None,biological_process|,molecular_function|,10,-0.1,0.787,10,0,0,-0.1,0.426,-0.426,0.692,0,0,-1.8,1.1
ENSMUSG00000021668,POLK,"polymerase (DNA directed), kappa",nucleus|nucleus|,"DNA replication|DNA-dependent DNA replication|DNA repair|nucleotide-excision repair, DNA gap filling|cellular response to DNA damage stimulus|DNA biosynthetic process|",DNA binding|damaged DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,-0.1,0.217,10,-0.1,0.249,-0.1,0.426,-0.426,0.692,0,0,-1.3,1.5
ENSMUSG00000037029,ZFP146,zinc finger protein 146,nucleus|nucleolus|cytoplasm|,"regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.3,2.03,-0.2,0.42,-0.42,0.694,0,0,-1.3,1.7
ENSMUSG00000074102,RBM15B,RNA binding motif protein 15B,nucleus|nucleoplasm|,"regulation of alternative mRNA splicing, via spliceosome|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.2,0.515,10,0,0,-0.1,0.419,-0.419,0.694,0,0,-1.8,1
ENSMUSG00000058186,GM13242,predicted gene 13242,cellular_component|,"hematopoietic progenitor cell differentiation|regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,5,-0.9,2.34,5,0,0,-0.8,0.419,-0.419,0.694,0,0,-2,1
ENSMUSG00000052137,RBM12B2,RNA binding motif protein 12 B2,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.1,0.178,10,0.1,0.429,0.1,0.411,0.411,0.697,0,0,-1.5,1.3
ENSMUSG00000025529,ZFP711,zinc finger protein 711,nucleus|extracellular vesicular exosome|,"positive regulation of transcription, DNA-templated|",sequence-specific DNA binding|,10,-0.3,0.698,10,0,0,-0.3,0.407,-0.407,0.699,0,0,-1.6,1.5
ENSMUSG00000094626,CECR6,"cat eye syndrome chromosome region, candidate 6",None,None,None,10,-0.1,0.189,10,-0.1,0.252,-0.1,0.402,-0.402,0.701,0,0,-1.4,1.4
ENSMUSG00000031816,MTHFSD,methenyltetrahydrofolate synthetase domain containing,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.2,0.224,10,0.1,0.402,-0.1,0.399,-0.399,0.701,0,0,-1.5,1.2
ENSMUSG00000006705,PKNOX1,Pbx/knotted 1 homeobox,nucleus|transcription factor complex|cytoplasm|,"angiogenesis|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|hemopoiesis|T cell differentiation|erythrocyte differentiation|camera-type eye development|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|protein heterodimerization activity|,10,-0.1,0.304,10,-0.1,0.127,-0.1,0.393,-0.393,0.703,0,0,-2,0.6
ENSMUSG00000022760,THAP7,THAP domain containing 7,nucleus|chromosome|nuclear speck|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|protein N-terminus binding|C2H2 zinc finger domain binding|,10,-0.1,0.102,10,0.6,0.426,-0.1,0.388,-0.388,0.705,0,0,-0.9,1.8
ENSMUSG00000026240,COPS7B,"COP9 (constitutive photomorphogenic) homolog, subunit 7b (Arabidopsis thaliana)",nucleus|cytoplasm|COP9 signalosome|COP9 signalosome|,cullin deneddylation|cullin deneddylation|,molecular_function|,10,0,0,10,0.2,1.03,0.2,0.386,0.386,0.706,0,0,-1.4,1.4
ENSMUSG00000026427,EIF2D,eukaryotic translation initiation factor 2D,nucleus|cytoplasm|cytosolic small ribosomal subunit|,formation of translation preinitiation complex|IRES-dependent translational initiation|translation|translational initiation|ribosome disassembly|,RNA binding|translation initiation factor activity|,10,0.3,0.306,10,0.1,0.25,0.2,0.382,0.382,0.707,0,0,-1.2,1.5
ENSMUSG00000028676,SRSF10,serine/arginine-rich splicing factor 10,intracellular|cell|nucleus|nucleoplasm|nucleoplasm|,"RNA splicing, via transesterification reactions|RNA splicing, via transesterification reactions|mRNA splicing, via spliceosome|regulation of transcription, DNA-templated|mRNA splice site selection|mRNA splice site selection|mRNA processing|mRNA export from nucleus|RNA splicing|cytoplasmic transport|cytoplasmic transport|negative regulation of mRNA splicing, via spliceosome|negative regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|unfolded protein binding|,10,0.3,0.189,10,0.1,0.461,0.1,0.382,0.382,0.707,0,0,-0.7,1.9
ENSMUSG00000034402,KCNH5,"potassium voltage-gated channel, subfamily H (eag-related), member 5",intracellular|integral component of plasma membrane|cell surface|membrane|integral component of membrane|,phosphorelay signal transduction system|transport|ion transport|potassium ion transport|signal transduction|regulation of G2/M transition of mitotic cell cycle|regulation of ion transmembrane transport|regulation of membrane potential|transmembrane transport|potassium ion transmembrane transport|,phosphorelay sensor kinase activity|signal transducer activity|ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|calmodulin binding|,10,-0.1,0.0417,10,-0.1,0.371,-0.1,0.378,-0.378,0.709,0,0,-1.4,1.4
ENSMUSG00000063785,UTP14A,"UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)",cellular_component|nucleus|small-subunit processome|,rRNA processing|biological_process|ribosome biogenesis|,poly(A) RNA binding|,10,0,0,10,-0.8,2.99,-0.1,0.372,-0.372,0.711,0,0,-2,0.4
ENSMUSG00000028777,GNAT3,"guanine nucleotide binding protein, alpha transducing 3",acrosomal vesicle|photoreceptor outer segment|photoreceptor inner segment|cytoplasm|cytoplasm|heterotrimeric G-protein complex|axoneme|apical plasma membrane|protein complex|,detection of chemical stimulus involved in sensory perception of bitter taste|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|detection of visible light|sensory perception of taste|sensory perception of taste|sensory perception of bitter taste|sensory perception of sweet taste|sensory perception of umami taste|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|signal transducer activity|GTP binding|G-protein coupled photoreceptor activity|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,-0.1,0.195,10,-0.7,0.77,-0.6,0.371,-0.371,0.712,0,0,-1.9,0.5
ENSMUSG00000001661,HOXC6,homeobox C6,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|embryonic skeletal system development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.2,0.994,0.1,0.37,0.37,0.712,0,0,-1.3,1.5
ENSMUSG00000020362,CNOT6,"CCR4-NOT transcription complex, subunit 6",nucleus|cytoplasm|membrane|CCR4-NOT complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|positive regulation of cell proliferation|positive regulation of cytoplasmic mRNA processing body assembly|gene silencing by RNA|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|nuclear-transcribed mRNA catabolic process, no-go decay|RNA phosphodiester bond hydrolysis, exonucleolytic|positive regulation of ligand-dependent nuclear receptor transcription coactivator activity|",RNA binding|nuclease activity|exonuclease activity|exoribonuclease activity|poly(A)-specific ribonuclease activity|hydrolase activity|metal ion binding|,10,0.2,0.394,10,0.1,0.209,0.1,0.366,0.366,0.713,0,0,-1.3,1.5
ENSMUSG00000054604,CGGBP1,CGG triplet repeat binding protein 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|double-stranded DNA binding|,10,-1.2,2.7,10,0.1,0.366,-0.1,0.365,-0.365,0.714,0,0,-2,0.7
ENSMUSG00000026788,ZBTB43,zinc finger and BTB domain containing 43,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.4,1.18,10,0.1,0.0526,0.1,0.359,0.359,0.716,0,0,-1,1.7
ENSMUSG00000074500,ZFP558,zinc finger protein 558,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.2,0.893,10,0,0,0.1,0.355,0.355,0.717,0,0,-1.4,1.5
ENSMUSG00000009535,RNMT,RNA (guanine-7-) methyltransferase,nucleus|mRNA cap binding complex|receptor complex|,7-methylguanosine mRNA capping|mRNA processing|methylation|RNA (guanine-N7)-methylation|mRNA methylation|,RNA binding|mRNA (guanine-N7-)-methyltransferase activity|methyltransferase activity|transferase activity|,10,-0.2,0.654,10,0,0,-0.1,0.353,-0.353,0.718,0,0,-1.3,1.6
ENSMUSG00000063954,HIST2H2AA1,"histone cluster 2, H2aa1",nucleus|extracellular vesicular exosome|,None,None,10,0,0,10,0.3,1.02,0.2,0.351,0.351,0.719,0,0,-1.7,1.2
ENSMUSG00000010362,RDM1,RAD52 motif 1,nucleus|nucleolus|cytoplasm|,biological_process|,nucleotide binding|molecular_function|nucleic acid binding|DNA binding|RNA binding|,10,-0.3,0.9,10,0.2,0.101,-0.3,0.348,-0.348,0.72,0,0,-1.7,1
ENSMUSG00000027439,GZF1,GDNF-inducible zinc finger protein 1,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|branching involved in ureteric bud morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0.2,0.572,0.2,0.344,0.344,0.721,0,0,-1.3,1.5
ENSMUSG00000029765,PLXNA4,plexin A4,intracellular|plasma membrane|membrane|integral component of membrane|,signal transduction|multicellular organismal development|nervous system development|axon guidance|cranial nerve morphogenesis|facial nerve morphogenesis|glossopharyngeal nerve morphogenesis|trigeminal nerve morphogenesis|vagus nerve morphogenesis|postganglionic parasympathetic nervous system development|chemorepulsion of branchiomotor axon|anterior commissure morphogenesis|sympathetic nervous system development|neuron projection morphogenesis|regulation of axon extension involved in axon guidance|regulation of negative chemotaxis|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|,receptor activity|protein binding|semaphorin receptor activity|,10,0.3,2.06,9,-0.1,0.32,-0.1,0.335,-0.335,0.725,0,0,-1.2,1.5
ENSMUSG00000006311,ETV2,ets variant 2,nucleus|,"in utero embryonic development|mesoderm formation|blastocyst development|placenta development|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|Notch signaling pathway|positive regulation of gene expression|positive regulation of gene expression|Wnt signaling pathway|hemopoiesis|erythrocyte differentiation|positive regulation of endothelial cell differentiation|positive regulation of transcription from RNA polymerase II promoter|blood vessel morphogenesis|BMP signaling pathway involved in mesodermal cell fate specification|positive regulation of mesoderm development|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.4,0.675,0.1,0.332,0.332,0.726,0,0,-0.7,1.9
ENSMUSG00000026459,MYOG,myogenin,nucleus|nucleus|nucleus|protein-DNA complex|,"ossification|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell cycle|multicellular organismal development|muscle organ development|skeletal muscle tissue development|skeletal muscle tissue development|negative regulation of cell proliferation|positive regulation of myotube differentiation|positive regulation of muscle atrophy|regulation of satellite cell proliferation|response to muscle activity involved in regulation of muscle adaptation|response to electrical stimulus involved in regulation of muscle adaptation|striated muscle atrophy|response to denervation involved in regulation of muscle adaptation|myotube differentiation|cell differentiation|mRNA transcription from RNA polymerase II promoter|positive regulation of myoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|skeletal muscle fiber development|positive regulation of skeletal muscle fiber development|positive regulation of cell cycle arrest|cellular response to lithium ion|cellular response to growth factor stimulus|cellular response to estradiol stimulus|regulation of myoblast fusion|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|core promoter binding|core promoter binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|chromatin DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|protein dimerization activity|E-box binding|,10,0,0,10,-0.3,1.5,-0.2,0.328,-0.328,0.727,0,0,-2,0.7
ENSMUSG00000036615,RFXAP,regulatory factor X-associated protein,nucleus|,"positive regulation of transcription, DNA-templated|",DNA binding|,10,-0.6,2.23,10,0.3,0.812,0.2,0.327,0.327,0.728,0,0,-1.8,1
ENSMUSG00000054939,ZFP174,zinc finger protein 174,nucleus|nucleus|cytoplasm|actin cytoskeleton|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-templated|",sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|transcription regulatory region DNA binding|metal ion binding|,10,0.4,0.732,10,-0.1,0.544,-0.1,0.326,-0.326,0.728,0,0,-1.2,1.6
ENSMUSG00000078878,GM14305,predicted gene 14305,cellular_component|,biological_process|,molecular_function|,8,0.2,0.688,8,0,0,0.1,0.323,0.323,0.729,0,0,-1.2,1.8
ENSMUSG00000008575,NFIB,nuclear factor I/B,intracellular|nucleus|nucleus|nucleolus|cerebellar mossy fiber|,"negative regulation of transcription from RNA polymerase II promoter|chondrocyte differentiation|DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of cell proliferation|glial cell differentiation|principal sensory nucleus of trigeminal nerve development|anterior commissure morphogenesis|lung development|forebrain development|hindbrain development|negative regulation of DNA binding|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|Clara cell differentiation|Type I pneumocyte differentiation|Type II pneumocyte differentiation|lung ciliated cell differentiation|commissural neuron axon guidance|negative regulation of mesenchymal cell proliferation involved in lung development|negative regulation of epithelial cell proliferation involved in lung morphogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription corepressor activity|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|,10,0.1,0.195,10,0.1,0.159,0.1,0.322,0.322,0.73,0,0,-1.1,1.8
ENSMUSG00000033882,RBM46,RNA binding motif protein 46,cellular_component|,biological_process|,nucleotide binding|molecular_function|nucleic acid binding|RNA binding|,10,0.1,0.324,10,-0.1,0.364,-0.1,0.321,-0.321,0.73,0,0,-1.5,1.2
ENSMUSG00000009941,NXF2,nuclear RNA export factor 2,intracellular|cell|nucleus|nuclear envelope|nuclear envelope|,RNA export from nucleus|RNA export from nucleus|poly(A)+ mRNA export from nucleus|,RNA binding|mRNA binding|protein binding|,10,0,0,10,0.2,0.614,0.1,0.32,0.32,0.73,0,0,-1.1,1.7
ENSMUSG00000032419,TBX18,T-box18,nucleus|Tle3-Aes complex|,"negative regulation of transcription from RNA polymerase II promoter|somitogenesis|positive regulation of mesenchymal cell proliferation|sinoatrial node development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|sensory perception of sound|anterior/posterior axis specification|morphogenesis of embryonic epithelium|positive regulation of cell-cell adhesion|cell differentiation|anatomical structure formation involved in morphogenesis|positive regulation of epithelial cell proliferation|smooth muscle cell differentiation|negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation|ureter development|cochlea morphogenesis|positive regulation of mesenchymal cell proliferation involved in ureter development|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II transcription factor binding|RNA polymerase II transcription corepressor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|protein heterodimerization activity|,7,0.1,0.0357,7,-0.1,0.491,-0.1,0.316,-0.316,0.732,0,0,-1.8,1.4
ENSMUSG00000037797,ADH4,"alcohol dehydrogenase 4 (class II), pi polypeptide",cytoplasm|,retinoid metabolic process|alcohol metabolic process|ethanol metabolic process|ethanol oxidation|cellular aldehyde metabolic process|cellular aldehyde metabolic process|retinol metabolic process|alcohol catabolic process|oxidation-reduction process|quinone metabolic process|,"NADPH:quinone reductase activity|alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase (NAD) activity|alcohol dehydrogenase activity, zinc-dependent|alcohol dehydrogenase activity, zinc-dependent|alditol:NADP+ 1-oxidoreductase activity|retinol dehydrogenase activity|all-trans retinal binding|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|benzaldehyde dehydrogenase activity|retinol binding|ethanol binding|metal ion binding|NAD binding|",10,0.2,0.903,10,0,0,0.2,0.313,0.313,0.733,0,0,-1.1,1.6
ENSMUSG00000018040,RRP7A,ribosomal RNA processing 7 homolog A (S. cerevisiae),cellular_component|,biological_process|,nucleotide binding|RNA binding|poly(A) RNA binding|,9,0.1,0.312,9,0.8,0.369,0.1,0.307,0.307,0.735,0,0,-0.8,2
ENSMUSG00000094870,ZFP131,zinc finger protein 131,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,6,0.1,0.31,8,-0.8,2.22,-0.4,0.298,-0.298,0.738,0,0,-2,0.7
ENSMUSG00000063455,D630045J12RIK,RIKEN cDNA D630045J12 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.139,10,-0.1,0.181,-0.1,0.292,-0.292,0.741,0,0,-1.9,0.9
ENSMUSG00000037513,SAMD4B,sterile alpha motif domain containing 4B,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",poly(A) RNA binding|,10,1,1.75,10,-0.2,0.403,-0.1,0.291,-0.291,0.741,0,0,-1,2
ENSMUSG00000042851,ZC3H6,zinc finger CCCH type containing 6,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.206,10,0.2,0.118,0.1,0.288,0.288,0.742,0,0,-1.2,1.6
ENSMUSG00000024206,RFX2,"regulatory factor X, 2 (influences HLA class II expression)",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|,10,0,0,10,0.3,0.685,0.1,0.282,0.282,0.744,0,0,-1,1.7
ENSMUSG00000010592,DAZL,deleted in azoospermia-like,cytoplasm|polysome|,oocyte maturation|regulation of translation|female meiosis II|multicellular organismal development|germ cell development|spermatogenesis|cell differentiation|positive regulation of meiosis|positive regulation of translational initiation|oogenesis|,nucleotide binding|nucleic acid binding|RNA binding|mRNA 3'-UTR binding|protein binding|translation activator activity|identical protein binding|,10,-0.1,0.0196,10,0.4,0.811,0.3,0.282,0.282,0.744,0,0,-0.9,1.7
ENSMUSG00000030738,EIF3C,"eukaryotic translation initiation factor 3, subunit C","cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex, eIF3m|",translation|translational initiation|translational initiation|,RNA binding|translation initiation factor activity|translation initiation factor activity|translation initiation factor binding|ribosome binding|poly(A) RNA binding|,8,0.3,0.59,7,-0.2,0.476,0.6,0.279,0.279,0.745,0,0,-0.9,2
ENSMUSG00000039473,UBN1,ubinuclein 1,nucleus|tight junction|cell junction|,DNA replication-independent nucleosome assembly|negative regulation of phosphatase activity|chromatin modification|keratinocyte differentiation|,DNA binding|transcription factor binding|,10,0.3,1.3,10,-0.2,0.99,-0.1,0.273,-0.273,0.748,0,0,-1.4,1.3
ENSMUSG00000095139,POU3F2,"POU domain, class 3, transcription factor 2",nucleus|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|epidermis development|astrocyte development|Schwann cell development|cerebral cortex radially oriented cell migration|forebrain ventricular zone progenitor cell division|hypothalamus cell differentiation|neurohypophysis development|myelination in peripheral nervous system|neuron differentiation|positive regulation of multicellular organism growth|regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of axonogenesis|cellular response to organic substance|",RNA polymerase II transcription coactivator activity|RNA polymerase II transcription coactivator activity|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|identical protein binding|sequence-specific DNA binding|sequence-specific DNA binding|HMG box domain binding|,10,0.2,1.5,10,-0.2,0.505,0.2,0.27,0.27,0.749,0,0,-0.7,2
ENSMUSG00000021485,MXD3,Max dimerization protein 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|protein binding|protein dimerization activity|,10,0,0,10,-0.3,1.22,-0.1,0.263,-0.263,0.751,0,0,-1.8,0.9
ENSMUSG00000049604,HOXB13,homeobox B13,nucleus|transcription factor complex|,"morphogenesis of an epithelium|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|regulation of growth|prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis|epithelial cell maturation involved in prostate gland development|",DNA binding|protein binding|sequence-specific DNA binding|,10,-0.2,0.519,10,0,0,-0.2,0.261,-0.261,0.752,0,0,-1.6,1.2
ENSMUSG00000029267,MTF2,metal response element binding transcription factor 2,nucleus|cytoplasm|ESC/E(Z) complex|,negative regulation of transcription from RNA polymerase II promoter|segment specification|chromatin modification|stem cell maintenance|positive regulation of transcription from RNA polymerase II promoter|stem cell differentiation|negative regulation of histone H3-K27 methylation|positive regulation of histone H3-K27 methylation|,DNA binding|protein binding|zinc ion binding|methylated histone binding|methylated histone binding|metal ion binding|,10,-0.4,1.16,10,-0.1,0.0381,-0.1,0.259,-0.259,0.753,0,0,-1.2,1.7
ENSMUSG00000029144,GTF3C2,"general transcription factor IIIC, polypeptide 2, beta",transcription factor TFIIIC complex|nucleus|,"transcription, DNA-templated|transcription from RNA polymerase III promoter|",DNA binding|,10,-0.1,0.385,10,0,0,-0.1,0.259,-0.259,0.753,0,0,-1.7,1.2
ENSMUSG00000001065,ZFP276,zinc finger protein (C2H2 type) 276,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|zinc ion binding|metal ion binding|,10,0.9,1.06,10,-0.1,0.146,0.1,0.248,0.248,0.757,0,0,-0.8,2
ENSMUSG00000038560,SP6,trans-acting transcription factor 6,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of cell proliferation|regulation of odontogenesis|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0.4,0.556,0.1,0.244,0.244,0.759,0,0,-0.9,1.8
ENSMUSG00000059316,SLC27A4,"solute carrier family 27 (fatty acid transporter), member 4",endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|plasma membrane|microvillus|membrane|membrane|integral component of membrane|brush border membrane|,very long-chain fatty acid metabolic process|very long-chain fatty acid metabolic process|medium-chain fatty acid transport|medium-chain fatty acid transport|long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|transport|lipid transport|metabolic process|long-chain fatty acid transport|very long-chain fatty acid catabolic process|skin development|long-chain fatty acid import|,"nucleotide binding|catalytic activity|acyl-CoA ligase activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|succinate-CoA ligase activity|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity|fatty acid ligase activity|ligase activity|3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity|benzoyl acetate-CoA ligase activity|2,4-dichlorobenzoate-CoA ligase activity|very long-chain fatty acid-CoA ligase activity|very long-chain fatty acid-CoA ligase activity|pivalate-CoA ligase activity|cyclopropanecarboxylate-CoA ligase activity|adipate-CoA ligase activity|citronellyl-CoA ligase activity|mentha-1,3-dione-CoA ligase activity|thiophene-2-carboxylate-CoA ligase activity|2,4,4-trimethylpentanoate-CoA ligase activity|cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity|3-hydroxypropionyl-CoA synthetase activity|perillic acid:CoA ligase (ADP-forming) activity|perillic acid:CoA ligase (AMP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity|pristanate-CoA ligase activity|malonyl-CoA synthetase activity|",10,0.1,0.0845,10,0.4,0.533,0.1,0.234,0.234,0.762,0,0,-1.3,1.6
ENSMUSG00000008384,SERTAD1,SERTA domain containing 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cell growth|positive regulation of transcription, DNA-templated|",protein binding|,10,0.4,0.869,10,-0.1,0.089,0.1,0.233,0.233,0.763,0,0,-1.1,1.5
ENSMUSG00000028863,MEAF6,MYST/Esa1-associated factor 6,nucleus|cytoplasm|centrosome|NuA4 histone acetyltransferase complex|MOZ/MORF histone acetyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H2A acetylation|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K12 acetylation|histone H3-K14 acetylation|",molecular_function|,10,0.1,0.0557,10,0.2,0.306,0.1,0.23,0.23,0.764,0,0,-0.6,2
ENSMUSG00000055633,ZFP580,zinc finger protein 580,nucleus|,"positive regulation of endothelial cell proliferation|positive regulation of leukocyte chemotaxis|transcription, DNA-templated|regulation of transcription, DNA-templated|chemotaxis|inflammatory response|positive regulation of endothelial cell migration|positive regulation of gene expression|positive regulation of interleukin-8 production|cellular response to hydrogen peroxide|",nucleic acid binding|DNA binding|metal ion binding|,10,0.2,0.46,10,0,0,0.1,0.224,0.224,0.766,0,0,-1,1.8
ENSMUSG00000061898,RBAK,RB-associated KRAB repressor,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|metal ion binding|,10,0.1,0.639,10,0,0,0.1,0.223,0.223,0.767,0,0,-1,1.9
ENSMUSG00000000730,DNMT3L,DNA (cytosine-5-)-methyltransferase 3-like,condensed nuclear chromosome|nucleus|nuclear heterochromatin|cytoplasm|cytosol|,"in utero embryonic development|placenta development|methylation|positive regulation of catalytic activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|chorionic trophoblast cell differentiation|genetic imprinting|",protein binding|enzyme activator activity|enzyme activator activity|methyltransferase activity|transferase activity|enzyme binding|enzyme binding|metal ion binding|,10,-0.8,0.788,10,0.3,1.79,0.1,0.222,0.222,0.767,0,0,-1.9,1
ENSMUSG00000038721,HOXB7,homeobox B7,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|myeloid cell differentiation|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.2,0.311,10,-0.2,1.11,-0.1,0.221,-0.221,0.767,0,0,-1.3,1.6
ENSMUSG00000036923,STOX1,storkhead box 1,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.1,0.464,10,0,0,0.1,0.22,0.22,0.768,0,0,-0.9,2
ENSMUSG00000040187,ARNTL2,aryl hydrocarbon receptor nuclear translocator-like 2,nucleus|transcription factor complex|nucleolus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|signal transduction|circadian rhythm|positive regulation of circadian rhythm|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|protein binding|protein dimerization activity|E-box binding|E-box binding|,10,-0.2,0.0951,10,0.2,0.322,0.1,0.219,0.219,0.768,0,0,-1.4,1.4
ENSMUSG00000037621,ATOH8,atonal homolog 8 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|cell differentiation|",DNA binding|protein dimerization activity|,10,0,0,10,0.2,1.25,0.1,0.218,0.218,0.768,0,0,-1.3,1.5
ENSMUSG00000054648,ZFP869,zinc finger protein 869,nucleus|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.7,1.91,10,0,0,0.1,0.217,0.217,0.769,0,0,-0.8,1.9
ENSMUSG00000042810,KRBA1,KRAB-A domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.58,10,0.1,0.344,-0.2,0.216,-0.216,0.769,0,0,-1.5,1.2
ENSMUSG00000067724,GBX1,gastrulation brain homeobox 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|adult walking behavior|proprioception|spinal cord motor neuron differentiation|neuron fate commitment|sensory neuron axon guidance|",DNA binding|sequence-specific DNA binding|,10,-0.1,0.508,10,0.4,1.23,-0.1,0.212,-0.212,0.771,0,0,-1.2,1.7
ENSMUSG00000047819,TIGD4,tigger transposable element derived 4,cellular_component|nucleus|,biological_process|,molecular_function|nucleic acid binding|DNA binding|,10,-0.1,0.0863,10,-0.1,0.147,-0.1,0.212,-0.212,0.771,0,0,-1.5,1.4
ENSMUSG00000027932,SLC27A3,"solute carrier family 27 (fatty acid transporter), member 3",mitochondrion|membrane|membrane|integral component of membrane|,long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|acyl-CoA metabolic process|metabolic process|,"nucleotide binding|catalytic activity|acyl-CoA ligase activity|fatty-acyl-CoA synthase activity|long-chain fatty acid-CoA ligase activity|succinate-CoA ligase activity|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity|fatty acid ligase activity|ligase activity|3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity|benzoyl acetate-CoA ligase activity|2,4-dichlorobenzoate-CoA ligase activity|pivalate-CoA ligase activity|cyclopropanecarboxylate-CoA ligase activity|adipate-CoA ligase activity|citronellyl-CoA ligase activity|mentha-1,3-dione-CoA ligase activity|thiophene-2-carboxylate-CoA ligase activity|2,4,4-trimethylpentanoate-CoA ligase activity|cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity|3-hydroxypropionyl-CoA synthetase activity|perillic acid:CoA ligase (ADP-forming) activity|perillic acid:CoA ligase (AMP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity|pristanate-CoA ligase activity|malonyl-CoA synthetase activity|",10,-0.2,0.925,10,0.2,0.939,0.1,0.211,0.211,0.771,0,0,-1.4,1.4
ENSMUSG00000021880,RNASE6,"ribonuclease, RNase A family, 6",extracellular vesicular exosome|,biological_process|,molecular_function|nucleic acid binding|nuclease activity|endonuclease activity|hydrolase activity|,10,-0.6,1.27,10,0,0,-0.1,0.21,-0.21,0.771,0,0,-1.9,0.8
ENSMUSG00000032745,GPBP1,GC-rich promoter binding protein 1,nucleus|nucleolus|cytoplasm|plasma membrane|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0.2,0.423,10,-0.2,0.319,-0.1,0.203,-0.203,0.774,0,0,-1.4,1.3
ENSMUSG00000047911,NPM2,nucleophosmin/nucleoplasmin 2,cytoplasmic chromatin|nuclear chromatin|nucleus|nucleus|,chromatin remodeling|chromatin remodeling|regulation of exit from mitosis|multicellular organismal development|single fertilization|embryo development|chromatin modification|positive regulation of catalytic activity|positive regulation of DNA replication|positive regulation of meiosis|positive regulation of DNA metabolic process|protein homooligomerization|,nucleic acid binding|chromatin binding|enzyme binding|,10,-0.2,0.383,10,0.2,0.8,0.1,0.202,0.202,0.774,0,0,-1.3,1.5
ENSMUSG00000037652,PHC3,polyhomeotic-like 3 (Drosophila),nucleus|actin cytoskeleton|PcG protein complex|PcG protein complex|PRC1 complex|intracellular membrane-bounded organelle|,multicellular organismal development|biological_process|,molecular_function|DNA binding|zinc ion binding|metal ion binding|,9,0.2,0.646,10,-0.2,0.773,0.1,0.2,0.2,0.775,0,0,-1,2
ENSMUSG00000078903,GM14391,predicted gene 14391,cellular_component|,biological_process|,molecular_function|,9,-0.2,1.21,9,0.1,0.016,-0.1,0.197,-0.197,0.776,0,0,-1.6,1.3
ENSMUSG00000078887,GM6710,predicted gene 6710,cellular_component|,biological_process|,molecular_function|,9,-0.2,1.21,9,0.1,0.016,-0.1,0.197,-0.197,0.776,0,0,-1.6,1.3
ENSMUSG00000045193,CIRBP,cold inducible RNA binding protein,nucleus|nucleus|cytoplasm|cytoplasm|cytoplasmic stress granule|,response to stress|response to UV|negative regulation of translation|stress granule assembly|positive regulation of translation|mRNA stabilization|,nucleotide binding|nucleic acid binding|RNA binding|mRNA 3'-UTR binding|translation repressor activity|poly(A) RNA binding|small ribosomal subunit rRNA binding|,10,0,0,10,0.1,0.295,0.1,0.193,0.193,0.778,0,0,-1.2,1.7
ENSMUSG00000051499,ZFP786,zinc finger protein 786,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.5,0.992,10,0.1,1.03,0.1,0.193,0.193,0.778,0,0,-1,2
ENSMUSG00000027173,DEPDC7,DEP domain containing 7,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,0.1,0.354,0.1,0.192,0.192,0.778,0,0,-1.2,1.6
ENSMUSG00000038116,PHF20,PHD finger protein 20,histone acetyltransferase complex|nucleus|cytoplasm|nuclear membrane|MLL1 complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|",DNA binding|zinc ion binding|histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|metal ion binding|histone acetyltransferase activity (H4-K16 specific)|,10,-0.1,0.384,10,0.1,0.387,-0.1,0.192,-0.192,0.778,0,0,-1.8,1
ENSMUSG00000039081,ZFP503,zinc finger protein 503,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cell proliferation|negative regulation of gene expression|neural precursor cell proliferation|G1 to G0 transition involved in cell differentiation|G1 to G0 transition involved in cell differentiation|",nucleic acid binding|metal ion binding|,10,0.1,0.111,10,0.1,0.0977,0.1,0.19,0.19,0.779,0,0,-1.5,1.5
ENSMUSG00000039275,FOXK2,forkhead box K2,nucleus|nucleus|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",magnesium ion binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|metal ion binding|,9,-0.2,0.706,9,0,0,-0.2,0.189,-0.189,0.779,0,0,-1.6,1.3
ENSMUSG00000039967,ZFP292,zinc finger protein 292,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0.4,0.568,0.1,0.188,0.188,0.78,0,0,-1.6,1.4
ENSMUSG00000027132,KATNBL1,katanin p80 subunit B like 1,nucleolus|,biological_process|,molecular_function|,10,0.2,0.686,10,0,0,0.1,0.186,0.186,0.781,0,0,-1.4,1.4
ENSMUSG00000028799,ZFP362,zinc finger protein 362,cellular_component|,biological_process|,molecular_function|,10,0.1,0.211,10,0.9,0.489,0.1,0.186,0.186,0.781,0,0,-0.7,2
ENSMUSG00000010461,EYA4,eyes absent 4 homolog (Drosophila),cellular_component|nucleus|cytoplasm|,"DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|multicellular organismal development|sensory perception of sound|chromatin modification|middle ear morphogenesis|",molecular_function|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|metal ion binding|,10,-0.2,0.395,10,0,0,-0.1,0.185,-0.185,0.781,0,0,-1.6,1.2
ENSMUSG00000059325,HOPX,HOP homeobox,nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|trophectodermal cell differentiation|trophectodermal cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|heart development|regulation of heart contraction|histone deacetylation|regulation of protein binding|positive regulation of skeletal muscle tissue regeneration|negative regulation of cell differentiation|lung alveolus development|positive regulation of striated muscle cell differentiation|",DNA binding|protein binding|,10,0.3,1.02,10,0,0,0.1,0.181,0.181,0.782,0,0,-0.9,1.8
ENSMUSG00000034765,DUSP5,dual specificity phosphatase 5,None,"inactivation of MAPK activity|endoderm formation|protein dephosphorylation|dephosphorylation|negative regulation of transcription, DNA-templated|",phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|,10,0.1,0.46,10,0,0,0.1,0.179,0.179,0.783,0,0,-1,1.9
ENSMUSG00000023411,NFATC4,"nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4",intracellular|nucleus|nucleus|transcription factor complex|cytoplasm|cytosol|cytosol|intermediate filament cytoskeleton|,"negative regulation of transcription from RNA polymerase II promoter|patterning of blood vessels|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|heart development|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|cell differentiation|positive regulation of tumor necrosis factor production|cellular response to UV|positive regulation of apoptotic process|cellular respiration|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of synaptic plasticity|smooth muscle cell differentiation|muscle cell development|cellular response to lithium ion|positive regulation of apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|peroxisome proliferator activated receptor binding|,10,0.5,0.447,10,-0.2,0.604,0.1,0.177,0.177,0.784,0,0,-1.4,1.6
ENSMUSG00000001504,IRX2,Iroquois related homeobox 2 (Drosophila),nucleus|,"regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding|,10,-0.2,0.626,10,0.3,1.93,0.3,0.177,0.177,0.784,0,0,-1.1,1.6
ENSMUSG00000026199,ANKZF1,ankyrin repeat and zinc finger domain containing 1,membrane|,biological_process|,molecular_function|metal ion binding|,10,0.2,0.506,10,-0.1,0.0842,-0.1,0.171,-0.171,0.787,0,0,-1.4,1.4
ENSMUSG00000039477,TNRC18,trinucleotide repeat containing 18,cellular_component|,biological_process|,molecular_function|chromatin binding|,9,-0.9,0.706,9,-0.1,0.37,-0.1,0.17,-0.17,0.787,0,0,-2,0.7
ENSMUSG00000027210,MEIS2,Meis homeobox 2,nucleus|,"eye development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|negative regulation of myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|regulation of RNA biosynthetic process|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|transcription cofactor activity|transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,-0.1,0.158,10,0.3,1.24,0.2,0.168,0.168,0.788,0,0,-1.6,1.3
ENSMUSG00000074272,CEACAM1,carcinoembryonic antigen-related cell adhesion molecule 1,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|ciliary membrane|extracellular vesicular exosome|,homophilic cell adhesion|viral process|positive regulation of MAP kinase activity|,virus receptor activity|protein kinase binding|protein homodimerization activity|,10,-0.2,0.138,10,-0.1,0.0469,-0.1,0.167,-0.167,0.788,0,0,-1.8,1
ENSMUSG00000021381,BARX1,BarH-like homeobox 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell-cell signaling|cell-cell signaling|tissue development|anterior/posterior pattern specification|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|epithelial cell differentiation|organ development|spleen development|anatomical structure development|digestive system development|",DNA binding|sequence-specific DNA binding|,10,0,0,10,0.2,0.642,0.1,0.167,0.167,0.788,0,0,-1,1.8
ENSMUSG00000020069,HNRNPH3,heterogeneous nuclear ribonucleoprotein H3,nucleus|,biological_process|,poly(A) RNA binding|,10,-0.2,1.01,10,0,0,-0.1,0.166,-0.166,0.789,0,0,-1.6,1.2
ENSMUSG00000082482,H2AFB2,"H2A histone family, member B2",nucleosome|nuclear nucleosome|nucleus|chromosome|transcriptionally active chromatin|,None,DNA binding|,10,0,0,10,-0.2,0.509,-0.1,0.163,-0.163,0.79,0,0,-1.8,1
ENSMUSG00000079662,NTN3,netrin 3,extracellular region|proteinaceous extracellular matrix|Golgi apparatus|,"regulation of transcription, DNA-templated|axonogenesis|myoblast fusion|",receptor binding|receptor binding|,10,0.1,0.234,10,0,0,0.1,0.163,0.163,0.79,0,0,-0.8,2
ENSMUSG00000038398,UPF3A,UPF3 regulator of nonsense transcripts homolog A (yeast),nucleus|cytoplasm|plasma membrane|exon-exon junction complex|,response to unfolded protein|positive regulation of translation|,mRNA binding|,10,0,0,10,0.1,0.354,0.1,0.163,0.163,0.79,0,0,-1.1,1.8
ENSMUSG00000037034,PAX1,paired box 1,nucleus|transcription factor complex|,"skeletal system development|skeletal system development|somitogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|cell proliferation|organ morphogenesis|CD4-positive, alpha-beta T cell differentiation|CD8-positive, alpha-beta T cell differentiation|positive regulation of transcription from RNA polymerase II promoter|thymus development|parathyroid gland development|bone morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.3,0.805,10,0,0,-0.1,0.152,-0.152,0.794,0,0,-1.7,1.2
ENSMUSG00000049764,ZFP280B,zinc finger protein 280B,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.758,10,0.1,0.551,0.1,0.148,0.148,0.796,0,0,-1.4,1.4
ENSMUSG00000015597,ZFP318,zinc finger protein 318,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|meiotic nuclear division|",nucleic acid binding|zinc ion binding|metal ion binding|,10,0.3,1.01,10,0,0,0.1,0.142,0.142,0.798,0,0,-1.1,1.7
ENSMUSG00000034422,PARP14,"poly (ADP-ribose) polymerase family, member 14",nucleus|cytoplasm|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|","nucleic acid binding|NAD+ ADP-ribosyltransferase activity|protein binding|transferase activity|transferase activity, transferring glycosyl groups|",10,0.3,0.887,10,0,0,-0.2,0.139,-0.139,0.799,0,0,-1.3,1.4
ENSMUSG00000055480,ZFP458,zinc finger protein 458,cellular_component|intracellular|,"regulation of transcription, DNA-templated|biological_process|",molecular_function|nucleic acid binding|metal ion binding|,10,0,0,10,-0.2,0.506,-0.1,0.128,-0.128,0.803,0,0,-1.6,1.2
ENSMUSG00000027102,HOXD8,homeobox D8,cellular_component|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|skeletal system morphogenesis|skeletal system morphogenesis|",molecular_function|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.1,0.211,10,-0.7,0.221,0.1,0.125,0.125,0.804,0,0,-2,0.9
ENSMUSG00000036972,ZIC4,zinc finger protein of the cerebellum 4,nucleus|,None,nucleic acid binding|DNA binding|metal ion binding|,10,0.1,0.174,10,0,0,0.1,0.125,0.125,0.804,0,0,-1.3,1.6
ENSMUSG00000039607,RBMS3,"RNA binding motif, single stranded interacting protein",cytoplasm|,positive regulation of translation|,nucleotide binding|nucleic acid binding|RNA binding|mRNA 3'-UTR binding|,10,-0.3,1.54,10,0,0,0.1,0.123,0.123,0.805,0,0,-1.2,1.6
ENSMUSG00000060032,H2AFJ,"H2A histone family, member J",nucleosome|nucleus|chromosome|extracellular vesicular exosome|,biological_process|,DNA binding|protein heterodimerization activity|,10,0.1,0.281,10,0,0,0.1,0.121,0.121,0.806,0,0,-1.1,1.8
ENSMUSG00000048373,FGFBP1,fibroblast growth factor binding protein 1,extracellular region|plasma membrane|cell surface|membrane|,cell-cell signaling|positive regulation of cell proliferation|positive regulation of fibroblast growth factor receptor signaling pathway|,fibroblast growth factor binding|growth factor binding|,10,-1,1.81,10,-0.1,0.259,-0.5,0.115,-0.115,0.808,0,0,-2,0.4
ENSMUSG00000054452,AES,amino-terminal enhancer of split,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|negative regulation of gene expression|Wnt signaling pathway|cellular response to extracellular stimulus|negative regulation of protein binding|regulation of growth|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of response to cytokine stimulus|response to interleukin-1|negative regulation of canonical Wnt signaling pathway|positive regulation of anoikis|",transcription corepressor activity|transcription corepressor activity|protein binding|,10,-0.2,0.641,10,0.3,0.346,-0.1,0.115,-0.115,0.808,0,0,-1.3,1.6
ENSMUSG00000064264,ZFP428,zinc finger protein 428,None,biological_process|,metal ion binding|,10,0,0,10,0.6,1.07,0.1,0.107,0.107,0.811,0,0,-0.9,1.9
ENSMUSG00000028528,DNAJC6,"DnaJ (Hsp40) homolog, subfamily C, member 6",synapse|,clathrin coat disassembly|clathrin coat disassembly|regulation of clathrin-mediated endocytosis|,molecular_function|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|hydrolase activity|SH3 domain binding|,10,0.5,2.23,10,-0.1,0.178,-0.1,0.101,-0.101,0.813,0,0,-0.9,1.7
ENSMUSG00000018347,ZKSCAN6,zinc finger with KRAB and SCAN domains 6,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0.2,0.366,0.1,0.101,0.101,0.813,0,0,-1.6,1.3
ENSMUSG00000040721,ZFHX2,zinc finger homeobox 2,nucleus|,adult behavior|,DNA binding|,10,0.2,0.61,10,-0.4,1.02,-0.1,0.0982,-0.0982,0.814,0,0,-1.7,1.1
ENSMUSG00000026565,POU2F1,"POU domain, class 2, transcription factor 1",nucleus|nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|olfactory placode formation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|lens induction in camera-type eye|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,0.1,0.171,10,0,0,0.1,0.0913,0.0913,0.817,0,0,-1.4,1.5
ENSMUSG00000048921,ZFP689,zinc finger protein 689,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle cell differentiation|",nucleic acid binding|DNA binding|metal ion binding|,10,0.1,0.0724,10,0.3,0.496,0.1,0.0884,0.0884,0.818,0,0,-1.1,1.7
ENSMUSG00000063146,CLIP2,CAP-GLY domain containing linker protein 2,cytoplasm|cytoskeleton|microtubule|microtubule associated complex|cytoplasmic microtubule|cytoplasmic microtubule|microtubule plus-end|,None,protein binding|microtubule binding|microtubule plus-end binding|microtubule plus-end binding|,10,0,0,10,-0.2,0.996,-0.1,0.0875,-0.0875,0.818,0,0,-1.6,1.4
ENSMUSG00000058638,ZFP110,zinc finger protein 110,intracellular|nucleus|nucleus|cytoplasm|centrosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|apoptotic process|regulation of JNK cascade|neuron apoptotic process|extrinsic apoptotic signaling pathway|retinal cell apoptotic process|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|neurotrophin p75 receptor binding|protein binding|sequence-specific DNA binding|metal ion binding|,10,-0.1,0.271,10,0.2,0.932,-0.1,0.087,-0.087,0.818,0,0,-1.7,1.1
ENSMUSG00000018076,MED13L,mediator complex subunit 13-like,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|molecular_function|,10,-0.4,1.18,10,0,0,-0.1,0.085,-0.085,0.819,0,0,-1.8,0.9
ENSMUSG00000042369,RBM45,RNA binding motif protein 45,nucleus|cytoplasm|,multicellular organismal development|nervous system development|biological_process|cell differentiation|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.1,0.0905,10,-0.2,0.644,-0.1,0.0812,-0.0812,0.82,0,0,-1.6,1.2
ENSMUSG00000026782,ABI2,abl-interactor 2,cytoplasm|cytosol|cytosol|cytoskeleton|cell-cell adherens junction|lamellipodium|filopodium|dendrite|SCAR complex|cell projection|,cellular component movement|learning or memory|actin polymerization or depolymerization|dendrite development|cell migration|Rac protein signal transduction|peptidyl-tyrosine phosphorylation|camera-type eye development|positive regulation of Arp2/3 complex-mediated actin nucleation|,SH3 domain binding|ubiquitin protein ligase binding|protein complex binding|Rac GTPase binding|proline-rich region binding|,10,0.2,0.0287,10,0.1,0.0889,0.1,0.0803,0.0803,0.821,0,0,-1,1.9
ENSMUSG00000034800,ZFP661,zinc finger protein 661,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.3,0.83,0.1,0.0778,0.0778,0.822,0,0,-1.5,1.3
ENSMUSG00000020091,EIF4EBP2,eukaryotic translation initiation factor 4E binding protein 2,intracellular|,regulation of translation|regulation of translational initiation|insulin receptor signaling pathway|negative regulation of translation|cAMP-mediated signaling|negative regulation of translational initiation|,protein binding|eukaryotic initiation factor 4E binding|,10,0.1,0.263,10,-0.4,1.36,0.1,0.0759,0.0759,0.822,0,0,-1.6,1.1
ENSMUSG00000036636,CLCN7,chloride channel 7,lysosome|lysosomal membrane|membrane|membrane|integral component of membrane|cytoplasmic vesicle|,transport|ion transport|chloride transport|response to pH|transmembrane transport|,nucleotide binding|ion channel activity|voltage-gated chloride channel activity|protein binding|ATP binding|antiporter activity|adenyl nucleotide binding|,10,0.3,0.461,10,0.1,0.00999,0.2,0.0739,0.0739,0.823,0,0,-0.9,1.8
ENSMUSG00000031379,PIR,pirin,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|myeloid cell differentiation|monocyte differentiation|oxidation-reduction process|regulation of RNA biosynthetic process|","transcription cofactor activity|quercetin 2,3-dioxygenase activity|quercetin 2,3-dioxygenase activity|oxidoreductase activity|metal ion binding|dioxygenase activity|",10,-0.1,0.0967,10,0,0,-0.1,0.0737,-0.0737,0.823,0,0,-1.4,1.6
ENSMUSG00000030382,SLC27A5,"solute carrier family 27 (fatty acid transporter), member 5",endoplasmic reticulum|endoplasmic reticulum|basal plasma membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|protein complex|,very long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|triglyceride mobilization|bile acid biosynthetic process|metabolic process|bile acid metabolic process|bile acid metabolic process|fatty acid transport|plasma membrane long-chain fatty acid transport|ketone body biosynthetic process|,nucleotide binding|catalytic activity|long-chain fatty acid-CoA ligase activity|ATP binding|fatty acid transporter activity|ligase activity|very long-chain fatty acid-CoA ligase activity|protein complex binding|cholate-CoA ligase activity|,10,0.1,0.215,10,-0.3,1.42,-0.3,0.0735,-0.0735,0.823,0,0,-1.6,1.2
ENSMUSG00000025207,SEMA4G,"sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G",plasma membrane|membrane|integral component of membrane|,multicellular organismal development|nervous system development|cell differentiation|,receptor activity|protein binding|,10,-0.1,0.203,10,0,0,-0.1,0.0699,-0.0699,0.825,0,0,-1.7,1.1
ENSMUSG00000020327,FGF22,fibroblast growth factor 22,nucleolus|Golgi apparatus|cell surface|,fibroblast growth factor receptor signaling pathway|,receptor binding|fibroblast growth factor receptor binding|protein binding|growth factor activity|,10,0.2,0.551,10,-0.3,0.958,-0.1,0.0693,-0.0693,0.825,0,0,-1.3,1.5
ENSMUSG00000040289,HEY1,hairy/enhancer-of-split related with YRPW motif 1,nucleus|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|blood vessel development|vasculogenesis|osteoblast development|outflow tract morphogenesis|atrioventricular valve morphogenesis|pulmonary valve morphogenesis|atrioventricular valve formation|epithelial to mesenchymal transition involved in endocardial cushion formation|endocardial cushion to mesenchymal transition involved in heart valve formation|endocardial cushion morphogenesis|cardiac ventricle morphogenesis|ventricular trabecula myocardium morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|anterior/posterior axis specification|negative regulation of gene expression|negative regulation of gene expression|mesenchymal cell development|dorsal aorta morphogenesis|umbilical cord morphogenesis|negative regulation of neuron differentiation|positive regulation of osteoblast differentiation|negative regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cardiac epithelial to mesenchymal transition|cardiac septum morphogenesis|ventricular septum morphogenesis|labyrinthine layer blood vessel development|artery development|arterial endothelial cell differentiation|Notch signaling involved in heart development|negative regulation of transcription regulatory region DNA binding|negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|regulation of vasculogenesis|",RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|protein binding transcription factor activity|protein binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|microsatellite binding|microsatellite binding|sequence-specific DNA binding|protein dimerization activity|,10,0.1,0.371,10,0,0,0.1,0.063,0.063,0.827,0,0,-1.2,1.7
ENSMUSG00000017607,TNS4,tensin 4,cytoplasm|cytoskeleton|focal adhesion|cell junction|,apoptotic process|protein localization|,molecular_function|actin binding|,10,0,0,10,-0.1,0.31,-0.1,0.0626,-0.0626,0.827,0,0,-1.4,1.5
ENSMUSG00000057156,HOMEZ,homeodomain leucine zipper-encoding gene,nucleus|nucleus|nucleolus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|,10,0,0,10,-0.2,0.438,-0.1,0.0586,-0.0586,0.828,0,0,-1.9,1
ENSMUSG00000036817,SUN1,Sad1 and UNC84 domain containing 1,acrosomal membrane|nucleus|nuclear envelope|nuclear envelope|integral component of nuclear inner membrane|cytoplasm|membrane|integral component of membrane|SUN-KASH complex|,nuclear envelope organization|cytoskeletal anchoring at nuclear membrane|nuclear matrix anchoring at nuclear membrane|,protein binding|lamin binding|,10,0,0,10,0.2,0.348,0.2,0.0498,0.0498,0.832,0,0,-1.2,1.6
ENSMUSG00000067942,ZFP160,zinc finger protein 160,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.412,10,-0.1,0.12,-0.1,0.0468,-0.0468,0.833,0,0,-1.6,1.3
ENSMUSG00000099032,TCF24,transcription factor 24,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.131,-0.1,0.0445,-0.0445,0.833,0,0,-1.6,1.3
ENSMUSG00000004542,PSG19,pregnancy specific glycoprotein 19,cellular_component|,female pregnancy|biological_process|,molecular_function|,10,0.1,0.245,10,0,0,0.1,0.044,0.044,0.834,0,0,-1.2,1.7
ENSMUSG00000030600,LRFN1,leucine rich repeat and fibronectin type III domain containing 1,plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,None,None,10,0,0,10,0.1,0.14,0.1,0.0403,0.0403,0.835,0,0,-1.5,1.4
ENSMUSG00000029868,TRPV6,"transient receptor potential cation channel, subfamily V, member 6",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|calcium ion transport|transmembrane transport|calcium ion import|calcium ion transmembrane transport|,ion channel activity|calcium channel activity|calcium channel activity|calmodulin binding|,10,0,0,10,0.1,0.575,0.1,0.0392,0.0392,0.835,0,0,-1.4,1.5
ENSMUSG00000078768,ZFP566,zinc finger protein 566,cellular_component|,biological_process|,molecular_function|metal ion binding|,5,0.6,0.0127,5,0.1,0.252,0.1,0.0387,0.0387,0.836,0,0,-1.3,2
ENSMUSG00000069476,ZFP616,zinc finger protein 616,cellular_component|,biological_process|,molecular_function|,10,0.2,0.767,10,-0.1,0.384,-0.1,0.0384,-0.0384,0.836,0,0,-1.5,1.5
ENSMUSG00000075600,ZC3H3,zinc finger CCCH type containing 3,nucleus|mRNA cleavage and polyadenylation specificity factor complex|,mRNA polyadenylation|regulation of mRNA export from nucleus|poly(A)+ mRNA export from nucleus|mRNA 3'-end processing|positive regulation of activin receptor signaling pathway|,SMAD binding|metal ion binding|R-SMAD binding|,9,0,0,10,0.2,0.163,0.1,0.0384,0.0384,0.836,0,0,-1.1,1.8
ENSMUSG00000070354,GM21975,N/A,None,None,None,6,0.2,0.503,6,0,0,0.1,0.0349,0.0349,0.837,0,0,-1.4,1.9
ENSMUSG00000019900,RFX6,"regulatory factor X, 6",nucleus|,"type B pancreatic cell differentiation|pancreatic A cell differentiation|pancreatic D cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell differentiation|endocrine pancreas development|glucose homeostasis|glucose homeostasis|positive regulation of transcription, DNA-templated|regulation of insulin secretion|regulation of insulin secretion|pancreatic epsilon cell differentiation|",DNA binding|protein binding|transcription regulatory region DNA binding|,10,-0.1,0.0608,10,0.1,0.234,0.1,0.0343,0.0343,0.837,0,0,-1.7,1.3
ENSMUSG00000029127,ZBTB49,zinc finger and BTB domain containing 49,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.1,0.319,10,0,0,0.1,0.033,0.033,0.838,0,0,-1.9,1.1
ENSMUSG00000050846,ZFP623,zinc finger protein 623,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|,9,-0.3,0.787,9,0.1,0.118,0.1,0.0294,0.0294,0.839,0,0,-1.5,1.5
ENSMUSG00000091086,GM5428,predicted gene 5428,cellular_component|ribosome|ribonucleoprotein complex|,biological_process|,molecular_function|,9,0.3,0.747,9,0,0,0.1,0.0283,0.0283,0.84,0,0,-0.9,1.9
ENSMUSG00000030148,CLEC4A2,"C-type lectin domain family 4, member a2",membrane|integral component of membrane|,immune system process|innate immune response|,carbohydrate binding|,10,0,0,10,-0.1,0.297,-0.1,0.0256,-0.0256,0.841,0,0,-1.7,1.3
ENSMUSG00000047143,DMRTA2,doublesex and mab-3 related transcription factor like family A2,nucleus|,"positive regulation of neuroblast proliferation|regulation of transcription, DNA-templated|cerebral cortex regionalization|skeletal muscle cell differentiation|neuron fate specification|dopaminergic neuron differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,0.2,0.786,10,0,0,0.1,0.0226,0.0226,0.842,0,0,-0.7,2
ENSMUSG00000036792,MBD5,methyl-CpG binding domain protein 5,nucleus|chromosome|chromocenter|extracellular vesicular exosome|,nervous system development|regulation of multicellular organism growth|glucose homeostasis|single-organism behavior|positive regulation of growth hormone receptor signaling pathway|,DNA binding|chromatin binding|,10,0.2,0.503,10,-0.8,2.51,0.1,0.0203,0.0203,0.843,0,0,-2,0.5
ENSMUSG00000044390,TIGD3,tigger transposable element derived 3,cellular_component|nucleus|,biological_process|,molecular_function|nucleic acid binding|DNA binding|,10,-0.1,0.456,10,0.1,0.0136,-0.1,0.0176,-0.0176,0.844,0,0,-1.6,1.3
ENSMUSG00000037197,RBM17,RNA binding motif protein 17,nucleus|spliceosomal complex|cytoplasm|,"RNA splicing, via transesterification reactions|alternative mRNA splicing, via spliceosome|mRNA processing|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|,9,0,0,10,0.1,0.0761,0.1,0.00928,0.00928,0.847,0,0,-1.4,1.5
ENSMUSG00000042548,ASXL1,additional sex combs like 1,nuclear chromatin|nucleus|PR-DUB complex|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|response to retinoic acid|negative regulation of peroxisome proliferator activated receptor signaling pathway|monoubiquitinated histone H2A deubiquitination|negative regulation of fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of retinoic acid receptor signaling pathway|negative regulation of retinoic acid receptor signaling pathway|bone development|",DNA binding|transcription coactivator activity|transcription corepressor activity|protein binding|retinoic acid receptor binding|peroxisome proliferator activated receptor binding|metal ion binding|,10,1,1.76,10,-0.2,0.762,-0.1,0.00915,-0.00915,0.847,0,0,-0.9,2
ENSMUSG00000040964,ARHGEF10L,Rho guanine nucleotide exchange factor (GEF) 10-like,cytoplasm|,regulation of Rho protein signal transduction|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0,0,10,-0.2,0.436,-0.1,0.00678,-0.00678,0.848,0,0,-1.7,1.2
ENSMUSG00000053552,EBF4,early B cell factor 4,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|transcription factor binding|metal ion binding|protein dimerization activity|,10,0,0,10,0.1,0.0101,0.1,0.00513,0.00513,0.849,0,0,-1.2,1.7
ENSMUSG00000031347,CETN2,centrin 2,intracellular|nucleus|cytoplasm|centrosome|centrosome|centriole|centriole|cytoskeleton|cilium|photoreceptor connecting cilium|ciliary basal body|XPC complex|,DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|centriole replication|regulation of cytokinesis|cell division|,nucleic acid binding|calcium ion binding|ATP binding|microtubule binding|ATP-dependent helicase activity|G-protein beta/gamma-subunit complex binding|heterotrimeric G-protein binding|metal ion binding|,10,-0.2,1.37,10,0,0,-0.1,0.0024,-0.0024,0.85,0,0,-1.5,1.4
ENSMUSG00000040929,RFX3,"regulatory factor X, 3 (influences HLA class II expression)",nuclear chromatin|nuclear chromatin|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|determination of left/right symmetry|cell differentiation|endocrine pancreas development|cilium assembly|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|cell maturation|regulation of insulin secretion|cilium-dependent cell motility|epithelial cilium movement involved in determination of left/right asymmetry|type B pancreatic cell maturation|positive regulation of type B pancreatic cell development|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|,10,-0.1,0.293,10,0,0,-0.1,0.000678,-0.000678,0.85,0,0,-1.7,1.3
ENSMUSG00000025213,KAZALD1,Kazal-type serine peptidase inhibitor domain 1,extracellular region|proteinaceous extracellular matrix|interstitial matrix|extracellular matrix|,ossification|regulation of cell growth|multicellular organismal development|cell differentiation|extracellular matrix organization|,insulin-like growth factor binding|,10,-0.1,0.0112,10,-0.7,1.03,-0.1,0.000104,-0.000104,0.85,0,0,-2,0.8
ENSMUSG00000002602,AXL,AXL receptor tyrosine kinase,extracellular space|intracellular|intracellular|cell|cell|plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,neuron migration|neuron migration|natural killer cell differentiation|positive regulation of cytokine-mediated signaling pathway|blood vessel remodeling|immune system process|protein phosphorylation|phagocytosis|phagocytosis|inflammatory response|enzyme linked receptor protein signaling pathway|spermatogenesis|phosphorylation|forebrain cell migration|cell differentiation|platelet activation|cellular response to extracellular stimulus|negative regulation of interferon-gamma production|negative regulation of tumor necrosis factor production|positive regulation of natural killer cell differentiation|secretion by cell|erythrocyte homeostasis|erythrocyte homeostasis|substrate adhesion-dependent cell spreading|cellular response to interferon-alpha|ovulation cycle|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|apoptotic cell clearance|apoptotic cell clearance|protein kinase B signaling|protein kinase B signaling|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|innate immune response|negative regulation of lymphocyte activation|positive regulation of protein kinase B signaling|positive regulation of protein kinase B signaling|vagina development|cellular response to hydrogen peroxide|cellular response to lipopolysaccharide|negative regulation of dendritic cell apoptotic process|,"nucleotide binding|phosphatidylserine binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|myosin heavy chain binding|phosphatidylinositol 3-kinase binding|protein heterodimerization activity|",10,0,0,10,0,0,0,0,0,0.85,0,0,-2,0.9
ENSMUSG00000022361,ZHX1,zinc fingers and homeoboxes 1,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|metal ion binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.3,1.6
ENSMUSG00000028137,CELF3,"CUGBP, Elav-like family member 3",nucleus|nucleus|cytoplasm|cytoplasm|,"regulation of alternative mRNA splicing, via spliceosome|mRNA processing|spermatogenesis|RNA splicing|sperm motility|positive regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|RNA binding|,10,0,0,10,-0.1,0.00457,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000096795,ZFP433,RIKEN cDNA 1700123A16 gene,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.5
ENSMUSG00000055053,NFIC,nuclear factor I/C,intracellular|nucleus|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|odontogenesis of dentin-containing tooth|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",core promoter proximal region DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|,10,0.1,0.342,10,-0.1,0.0239,0,0,0,0.85,0,0,-1.5,1.4
ENSMUSG00000040270,BACH2,BTB and CNC homology 2,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0,0,10,0.1,0.0984,0,0,0,0.85,0,0,-0.9,2
ENSMUSG00000052406,REXO4,"REX4, RNA exonuclease 4 homolog (S. cerevisiae)",nucleus|nucleolus|,biological_process|,nucleic acid binding|nuclease activity|exonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|poly(A) RNA binding|retroviral 3' processing activity|,10,-0.6,0.813,10,0.2,0.322,0,0,0,0.85,0,0,-1.9,1
ENSMUSG00000029697,FEZF1,Fez family zinc finger 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|axon guidance|negative regulation of cell proliferation|telencephalon development|olfactory bulb development|forebrain anterior/posterior pattern specification|cell differentiation|forebrain development|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|nucleic acid binding|DNA binding|metal ion binding|,10,-0.2,0.116,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000036995,ASAP3,"ArfGAP with SH3 domain, ankyrin repeat and PH domain 3",ruffle|cytoplasm|focal adhesion|,cell migration|regulation of ARF GTPase activity|positive regulation of ARF GTPase activity|regulation of stress fiber assembly|,ARF GTPase activator activity|zinc ion binding|metal ion binding|,10,-0.1,0.333,10,0,0,0,0,0,0.85,0,0,-1.8,1.1
ENSMUSG00000021681,AGGF1,angiogenic factor with G patch and FHA domains 1,extracellular region|cytoplasm|perinuclear region of cytoplasm|,angiogenesis|positive regulation of endothelial cell proliferation|cell adhesion|multicellular organismal development|cell differentiation|positive regulation of angiogenesis|,nucleic acid binding|,10,-0.2,0.651,10,0.2,0.191,0,0,0,0.85,0,0,-1.5,1.4
ENSMUSG00000023079,GTF2IRD1,general transcription factor II I repeat domain-containing 1,nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|embryo development|transition between slow and fast fiber|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.2,0.744,10,0,0,0,0,0,0.85,0,0,-1.8,1.1
ENSMUSG00000000942,HOXA4,homeobox A4,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.2,0.109,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000038718,PBX3,pre B cell leukemia homeobox 3,nucleus|transcription factor complex|,"regulation of respiratory gaseous exchange by neurological system process|transcription, DNA-templated|regulation of transcription, DNA-templated|respiratory gaseous exchange|adult locomotory behavior|dorsal spinal cord development|neuron development|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.1,0.26,10,0,0,0,0,0,0.85,0,0,-1.3,1.6
ENSMUSG00000024518,RAX,retina and anterior neural fold homeobox,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|pattern specification process|brain development|hypothalamus development|camera-type eye development|positive regulation of transcription from RNA polymerase II promoter|limb development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1,1.9
ENSMUSG00000037868,EGR2,early growth response 2,nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein export from nucleus|rhythmic behavior|rhythmic behavior|motor neuron axon guidance|Schwann cell differentiation|rhombomere 3 development|facial nerve structural organization|rhombomere 3 formation|rhombomere 5 formation|regulation of ossification|response to insulin|brain segmentation|skeletal muscle cell differentiation|myelination|negative regulation of apoptotic process|fat cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of neuronal synaptic plasticity|cellular response to organic substance|cellular response to cAMP|cellular response to gonadotropin stimulus|","RNA polymerase II activating transcription factor binding|nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|ubiquitin protein ligase binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|transcription regulatory region DNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|HMG box domain binding|",10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000029587,ZFP12,zinc finger protein 12,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.1,0.129,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000044646,ZBTB7C,zinc finger and BTB domain containing 7C,None,None,nucleic acid binding|metal ion binding|,10,0.1,0.185,10,0.9,0.124,0,0,0,0.85,0,0,-0.7,2
ENSMUSG00000055210,FOXD2,forkhead box D2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.1,0.128,10,0.1,0.466,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000033565,RBFOX2,"RNA binding protein, fox-1 homolog (C. elegans) 2",nucleus|nucleus|cytoplasm|,"regulation of alternative mRNA splicing, via spliceosome|regulation of alternative mRNA splicing, via spliceosome|mRNA processing|RNA splicing|regulation of definitive erythrocyte differentiation|radial glia guided migration of Purkinje cell|intracellular estrogen receptor signaling pathway|regulation of RNA splicing|negative regulation of transcription, DNA-templated|dendrite morphogenesis|neuromuscular process controlling balance|",nucleotide binding|nucleic acid binding|transcription corepressor activity|RNA binding|RNA binding|mRNA binding|protein binding|transcription factor binding|poly(A) RNA binding|,10,-0.2,0.0738,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000045493,BHLHE23,"basic helix-loop-helix family, member e23",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|retinal rod cell development|negative regulation of retinal cell programmed cell death|post-embryonic eye morphogenesis|",DNA binding|protein dimerization activity|,10,0,0,10,0.3,0.804,0,0,0,0.85,0,0,-1,1.9
ENSMUSG00000059689,ZFP637,zinc finger protein 637,nucleus|,biological_process|,nucleic acid binding|metal ion binding|,10,-0.1,0.641,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000005718,TFAP4,transcription factor AP4,nucleus|nucleus|transcriptional repressor complex|,"regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein complex assembly|protein complex assembly|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|negative regulation of cell proliferation|negative regulation of gene expression|positive regulation of apoptotic process|negative regulation of DNA binding|negative regulation by host of viral transcription|positive regulation by host of viral transcription|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of cell cycle arrest|cellular response to dexamethasone stimulus|positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|histone deacetylase binding|histone deacetylase binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|E-box binding|E-box binding|,10,-0.1,0.024,10,0.1,0.325,0,0,0,0.85,0,0,-1,1.9
ENSMUSG00000070034,SP110,Sp110 nuclear body protein,nucleus|nucleolus|,"immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|response to bacterium|positive regulation of apoptotic process|innate immune response|",DNA binding|,8,0,0,8,0,0,0,0,0,0.85,0,0,-2,1.2
ENSMUSG00000039634,ZFP189,zinc finger protein 189,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.3,1.8
ENSMUSG00000058402,ZFP420,zinc finger protein 420,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.1,0.173,10,0,0,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000025813,HOMER2,homer homolog 2 (Drosophila),nucleus|nucleolus|cytoplasm|cytoplasm|plasma membrane|membrane|cell junction|dendrite|neuronal cell body|apical part of cell|synapse|postsynaptic membrane|,G-protein coupled glutamate receptor signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|calcium-mediated signaling using intracellular calcium source|behavioral response to cocaine|chemical homeostasis within a tissue|,actin binding|protein binding|protein domain specific binding|GKAP/Homer scaffold activity|glutamate receptor binding|G-protein coupled glutamate receptor binding|protein homodimerization activity|protein heterodimerization activity|,10,0.2,0.29,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000028749,PLA2G2F,"phospholipase A2, group IIF",extracellular region|,lipid metabolic process|phospholipid metabolic process|lipid catabolic process|,phospholipase A2 activity|calcium ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000038691,MBD3L1,methyl-CpG binding domain protein 3-like 1,nucleus|cytoplasm|plasma membrane|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",None,10,-0.2,0.476,10,0.3,0.809,0,0,0,0.85,0,0,-1.5,1.4
ENSMUSG00000036898,ZFP157,zinc finger protein 157,cellular_component|,regulation of cell fate commitment|lung alveolus development|mammary gland morphogenesis|,molecular_function|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-2,1.1
ENSMUSG00000038538,UBN2,ubinuclein 2,extracellular space|nucleus|,biological_process|,molecular_function|,10,0.1,0.111,10,-0.2,0.314,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000028707,DMBX1,diencephalon/mesencephalon homeobox 1,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|adult feeding behavior|adult feeding behavior|adult locomotory behavior|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|protein heterodimerization activity|,10,0.1,0.182,10,0,0,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000022708,ZBTB20,zinc finger and BTB domain containing 20,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.5
ENSMUSG00000024235,MAP3K8,mitogen-activated protein kinase kinase kinase 8,cytoplasm|,MAPK cascade|activation of MAPKK activity|immune system process|protein phosphorylation|cell cycle|signal transduction|phosphorylation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",9,0,0,9,0.8,0.309,0,0,0,0.85,0,0,-0.8,2
ENSMUSG00000022469,RAPGEF3,Rap guanine nucleotide exchange factor (GEF) 3,intracellular|cytoplasm|cAMP-dependent protein kinase complex|membrane|extracellular vesicular exosome|,angiogenesis|regulation of protein phosphorylation|small GTPase mediated signal transduction|Rap protein signal transduction|positive regulation of Rap GTPase activity|intracellular signal transduction|positive regulation of GTPase activity|positive regulation of angiogenesis|regulation of small GTPase mediated signal transduction|positive regulation of stress fiber assembly|establishment of endothelial barrier|cellular response to cAMP|regulation of actin cytoskeleton reorganization|,nucleotide binding|guanyl-nucleotide exchange factor activity|cAMP-dependent protein kinase regulator activity|Rap guanyl-nucleotide exchange factor activity|cAMP binding|,10,0,0,10,0.7,0.171,0,0,0,0.85,0,0,-0.9,2
ENSMUSG00000000244,TSPAN32,tetraspanin 32,intracellular|cell surface|membrane|integral component of membrane|integrin alphaIIb-beta3 complex|,cytoskeleton organization|integrin-mediated signaling pathway|blood coagulation|hemostasis|negative regulation of cell proliferation|negative regulation of myeloid dendritic cell activation|defense response to protozoan|regulation of defense response to virus|platelet aggregation|,molecular_function|,10,-0.3,0.62,10,0.1,0.0277,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000030411,NOVA2,neuro-oncological ventral antigen 2,None,regulation of RNA metabolic process|,RNA binding|protein binding|poly(A) RNA binding|,10,0,0,10,-0.3,0.529,0,0,0,0.85,0,0,-1.8,1.2
ENSMUSG00000027018,HAT1,histone aminotransferase 1,nuclear chromatin|nucleus|intracellular membrane-bounded organelle|protein complex|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|chromatin silencing at telomere|chromatin modification|histone acetylation|,"histone acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,0.1,0.391,10,-0.7,0.873,0,0,0,0.85,0,0,-1.9,1.2
ENSMUSG00000052942,GLIS3,GLIS family zinc finger 3,nucleus|nucleus|Golgi apparatus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000053134,SUPT7L,suppressor of Ty 7-like,nucleus|STAGA complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|histone H3 acetylation|maintenance of protein location in nucleus|regulation of RNA biosynthetic process|",transcription coactivator activity|histone acetyltransferase activity|,10,0,0,10,0.5,1.43,0,0,0,0.85,0,0,-1,1.8
ENSMUSG00000031609,SAP30,sin3 associated polypeptide,histone deacetylase complex|nucleus|Sin3 complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle cell differentiation|",DNA binding|transcription corepressor activity|protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000025216,LBX1,ladybird homeobox homolog 1 (Drosophila),nucleus|transcription factor complex|,"heart looping|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|muscle organ development|negative regulation of cell proliferation|spinal cord motor neuron differentiation|regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification|cell differentiation|negative regulation of neuron differentiation|neuron fate commitment|neuron fate determination|neuron fate determination|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.4,0.737,10,0,0,0,0,0,0.85,0,0,-1.9,0.9
ENSMUSG00000028946,HES3,hairy and enhancer of split 3 (Drosophila),nucleus|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|midbrain-hindbrain boundary morphogenesis|oculomotor nerve development|trochlear nerve development|hindbrain morphogenesis|neural tube development|midbrain development|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of neurogenesis|regulation of timing of neuron differentiation|",DNA binding|transcription factor binding|protein dimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000030757,ZKSCAN2,zinc finger with KRAB and SCAN domains 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|metal ion binding|,10,0,0,10,-0.4,1.29,0,0,0,0.85,0,0,-1.6,1.2
ENSMUSG00000002057,FOXN1,forkhead box N1,nucleus|,"hair follicle development|lymphocyte homeostasis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|cell proliferation|epidermis development|keratinocyte differentiation|keratinocyte differentiation|regulation of T cell differentiation in thymus|nail development|thymus development|thymus development|epithelial cell proliferation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.4,0.306,10,0,0,0,0,0,0.85,0,0,-1.8,1.2
ENSMUSG00000024154,GTF2A1L,"general transcription factor IIA, 1-like",nucleus|transcription factor TFIIA complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|cognition|",DNA binding|protein binding|,10,-0.5,1.86,10,0,0,0,0,0,0.85,0,0,-2,0.8
ENSMUSG00000067438,HMX1,H6 homeobox 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|DNA binding|sequence-specific DNA binding|,10,0.1,0.179,10,0,0,0,0,0,0.85,0,0,-1.3,1.7
ENSMUSG00000091294,GLIS3,GLIS family zinc finger 3,nucleus|nucleus|Golgi apparatus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0.1,0.532,0,0,0,0.85,0,0,-0.7,2
ENSMUSG00000056854,POU3F4,"POU domain, class 3, transcription factor 4",intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|sensory perception of sound|forebrain neuron differentiation|inner ear development|cochlea morphogenesis|negative regulation of mesenchymal cell apoptotic process|",DNA binding|AT DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000034538,ZFP418,zinc finger protein 418,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,-0.2,0.419,0,0,0,0.85,0,0,-1.2,1.8
ENSMUSG00000019826,ZBTB24,zinc finger and BTB domain containing 24,nucleus|,"hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.6,1.81,0,0,0,0.85,0,0,-2,0.7
ENSMUSG00000035580,KCNH8,"potassium voltage-gated channel, subfamily H (eag-related), member 8",integral component of plasma membrane|membrane|integral component of membrane|,phosphorelay signal transduction system|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transport|ion transport|potassium ion transport|signal transduction|regulation of ion transmembrane transport|regulation of membrane potential|negative regulation of apoptotic process|transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,phosphorelay sensor kinase activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|signal transducer activity|ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|potassium channel activity|,10,-0.3,0.245,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000035285,NAT14,N-acetyltransferase 14,cellular_component|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|","molecular_function|DNA binding|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0,0,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000042419,NFKBIL1,nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1,nucleus|nucleus|cytosol|intermediate filament cytoskeleton|,I-kappaB kinase/NF-kappaB signaling|negative regulation of lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|negative regulation of tumor necrosis factor production|negative regulation of toll-like receptor signaling pathway|cellular response to lipopolysaccharide|,molecular_function|,10,0.1,0.0663,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000037214,THAP1,"THAP domain containing, apoptosis associated protein 1",nucleus|,"endothelial cell proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|regulation of mitotic cell cycle|",nucleic acid binding|DNA binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,9,0,0,10,0,0,0,0,0,0.85,0,0,-1.1,2
ENSMUSG00000022738,GSC2,goosecoid homebox 2,nucleus|,regulation of transcription from RNA polymerase II promoter|,DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0.1,0.239,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000046668,CXXC5,CXXC finger 5,nucleus|nucleolus|cytoplasm|intracellular membrane-bounded organelle|,signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|,DNA binding|signal transducer activity|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000063242,TGIF2LX2,"TGFB-induced factor homeobox 2-like, X-linked 2",cellular_component|,biological_process|,molecular_function|,2,0,0,2,0,0,0,0,0,0.85,0,0,-2,1.7
ENSMUSG00000066721,ZFP575,zinc finger protein 575,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000096225,LHX8,LIM homeobox protein 8,female germ cell nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|learning or memory|female gonad development|forebrain neuron differentiation|forebrain neuron development|odontogenesis of dentin-containing tooth|",DNA binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,-0.1,0.223,0,0,0,0.85,0,0,-1.4,1.5
ENSMUSG00000014603,ALX3,aristaless-like homeobox 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|regulation of apoptotic process|embryonic skeletal system morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000041298,KATNAL1,katanin p60 subunit A-like 1,cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|,ATP catabolic process|spermatogenesis|microtubule severing|,nucleotide binding|ATP binding|microtubule binding|microtubule-severing ATPase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000055991,ZKSCAN5,zinc finger with KRAB and SCAN domains 5,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.3,1.7
ENSMUSG00000001815,EVX2,even skipped homeotic gene 2 homolog,nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|limb morphogenesis|limb morphogenesis|",DNA binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.5
ENSMUSG00000023333,GCM1,glial cells missing homolog 1 (Drosophila),nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of transcription from RNA polymerase II promoter|astrocyte fate commitment|positive regulation of syncytium formation by plasma membrane fusion|positive regulation of syncytium formation by plasma membrane fusion|branching involved in labyrinthine layer morphogenesis|cell differentiation involved in embryonic placenta development|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|zinc ion binding|metal ion binding|,10,0.3,0.294,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000004936,MAP2K1,mitogen-activated protein kinase kinase 1,nucleus|cytoplasm|mitochondrion|early endosome|late endosome|Golgi apparatus|Golgi apparatus|cytosol|cytosol|cytoskeleton|microtubule|plasma membrane|focal adhesion|cell cortex|axon|dendrite|dendrite cytoplasm|perikaryon|perinuclear region of cytoplasm|extracellular vesicular exosome|,MAPK cascade|MAPK cascade|activation of MAPK activity|activation of MAPK activity|activation of MAPK activity|regulation of vascular smooth muscle contraction|protein phosphorylation|protein phosphorylation|protein phosphorylation|response to oxidative stress|cell cycle arrest|mitotic nuclear division|cell proliferation|negative regulation of cell proliferation|positive regulation of gene expression|phosphorylation|neuron differentiation|neuron differentiation|keratinocyte differentiation|positive regulation of cell migration|positive regulation of Ras GTPase activity|melanosome transport|regulation of stress-activated MAPK cascade|positive regulation of transcription elongation from RNA polymerase II promoter|negative regulation of homotypic cell-cell adhesion|peptidyl-tyrosine dephosphorylation|positive regulation of cell differentiation|positive regulation of Ras protein signal transduction|vesicle transport along microtubule|Golgi inheritance|response to axon injury|neuron projection morphogenesis|cell motility|protein heterooligomerization|response to glucocorticoid|placenta blood vessel development|labyrinthine layer development|positive regulation of protein serine/threonine kinase activity|regulation of Golgi inheritance|cellular senescence|regulation of early endosome to late endosome transport|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|MAP kinase kinase activity|protein serine/threonine/tyrosine kinase activity|protein tyrosine kinase activity|receptor signaling protein tyrosine phosphatase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Ras GTPase binding|protein kinase binding|mitogen-activated protein kinase kinase kinase binding|protein serine/threonine kinase activator activity|",10,-0.1,0.205,10,0.2,0.0117,0,0,0,0.85,0,0,-1.1,1.7
ENSMUSG00000068154,INSM1,insulinoma-associated 1,nucleus|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of protein phosphorylation|type B pancreatic cell differentiation|pancreatic A cell differentiation|type B pancreatic cell development|noradrenergic neuron development|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|multicellular organismal development|nervous system development|negative regulation of cell proliferation|regulation of gene expression|cell differentiation|endocrine pancreas development|endocrine system development|norepinephrine biosynthetic process|regulation of protein complex assembly|positive regulation of cell differentiation|transdifferentiation|adrenal chromaffin cell differentiation|sympathetic ganglion development|positive regulation of cell cycle arrest|positive regulation of neural precursor cell proliferation|",core promoter binding|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|cyclin binding|chromatin DNA binding|histone deacetylase binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000000617,GRM6,"glutamate receptor, metabotropic 6",Golgi membrane|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|new growing cell tip|presynaptic membrane|cell projection|postsynaptic membrane|,"signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|visual perception|locomotory behavior|response to stimulus|detection of light stimulus involved in visual perception|sensory perception of light stimulus|regulation of synaptic transmission, glutamatergic|retina development in camera-type eye|positive regulation of calcium ion import|",adenylate cyclase inhibiting G-protein coupled glutamate receptor activity|group III metabotropic glutamate receptor activity|group III metabotropic glutamate receptor activity|signal transducer activity|G-protein coupled receptor activity|glutamate receptor activity|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000039485,TSPYL4,TSPY-like 4,cellular_component|nucleus|,nucleosome assembly|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.2
ENSMUSG00000030544,MESP1,mesoderm posterior 1,nucleus|,"heart looping|heart morphogenesis|secondary heart field specification|embryonic heart tube morphogenesis|cardiac atrium formation|cardiac ventricle formation|sinus venosus morphogenesis|growth involved in heart morphogenesis|cardioblast migration|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|Notch signaling pathway|multicellular organismal development|mesodermal cell migration|neurogenesis|signal transduction involved in regulation of gene expression|positive regulation of Notch signaling pathway involved in heart induction|negative regulation of mesodermal cell fate specification|negative regulation of endodermal cell fate specification|endothelial cell differentiation|positive regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of striated muscle cell differentiation|cardiac muscle cell differentiation|cardiac cell fate determination|sinoatrial node cell differentiation|cardiac vascular smooth muscle cell differentiation|cardioblast migration to the midline involved in heart field formation|positive regulation of hepatocyte differentiation|positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|enhancer binding|transcription regulatory region DNA binding|protein dimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000036139,HOXC9,homeobox C9,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|embryonic skeletal system morphogenesis|embryonic skeletal system development|",DNA binding|sequence-specific DNA binding|,10,-0.3,0.617,10,0.1,0.0307,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000056413,ADAP1,ArfGAP with dual PH domains 1,nucleus|cytoplasm|plasma membrane|,regulation of GTPase activity|positive regulation of GTPase activity|,"phosphatidylinositol-3,4,5-trisphosphate binding|ARF GTPase activator activity|metal ion binding|",9,0,0,9,0,0,0,0,0,0.85,0,0,-1.4,1.7
ENSMUSG00000022721,TRMT2A,TRM2 tRNA methyltransferase 2A,None,methylation|,"nucleotide binding|rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.3,0.325,10,0,0,0,0,0,0.85,0,0,-1.8,1
ENSMUSG00000060586,H2-EB1,"histocompatibility 2, class II antigen E beta",extracellular space|lysosomal membrane|membrane|membrane|integral component of membrane|late endosome membrane|MHC class II protein complex|extracellular vesicular exosome|,immune system process|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|immune response|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|response to interferon-gamma|,protein binding|,10,0.3,0.564,10,-0.4,0.959,0,0,0,0.85,0,0,-2,0.9
ENSMUSG00000070291,DDX43,DEAD (Asp-Glu-Ala-Asp) box polypeptide 43,intracellular|,biological_process|,nucleotide binding|molecular_function|helicase activity|ATP binding|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000032735,ABLIM3,"actin binding LIM protein family, member 3",stress fiber|cytoplasm|lamellipodium|,"transcription, DNA-templated|cytoskeleton organization|lamellipodium assembly|actin cytoskeleton organization|cilium assembly|positive regulation of transcription from RNA polymerase II promoter|",molecular_function|actin binding|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000045757,ZFP764,zinc finger protein 764,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.1,1.9
ENSMUSG00000078862,GM14326,predicted gene 14326,cellular_component|,biological_process|,molecular_function|,10,0.3,0.445,10,-0.1,0.433,0,0,0,0.85,0,0,-1.3,1.6
ENSMUSG00000032357,TINAG,tubulointerstitial nephritis antigen,basement membrane|,cell adhesion|,None,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.4,1.7
ENSMUSG00000026707,NSUN6,NOL1/NOP2/Sun domain family member 6,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,-0.2,0.357,0,0,0,0.85,0,0,-1.4,1.5
ENSMUSG00000060397,ZFP128,zinc finger protein 128,nucleus|,negative regulation of transcription from RNA polymerase II promoter|BMP signaling pathway|,protein binding|metal ion binding|,10,-0.1,0.121,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000051390,ZBTB22,zinc finger and BTB domain containing 22,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000053414,HUNK,hormonally upregulated Neu-associated kinase,None,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.3,1.27,10,0.1,0.347,0,0,0,0.85,0,0,-1.7,1.1
ENSMUSG00000015053,GATA2,GATA binding protein 2,nucleus|nucleus|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|urogenital system development|cell fate determination|embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|phagocytosis|ventral spinal cord interneuron differentiation|cell differentiation in hindbrain|commitment of neuronal cell to specific neuron type in forebrain|central nervous system neuron development|pituitary gland development|cell differentiation|neuron differentiation|somatic stem cell maintenance|regulation of histone acetylation|eosinophil fate commitment|inner ear morphogenesis|negative regulation of fat cell differentiation|negative regulation of fat cell differentiation|negative regulation of myeloid cell differentiation|positive regulation of erythrocyte differentiation|negative regulation of macrophage differentiation|positive regulation of megakaryocyte differentiation|negative regulation of Notch signaling pathway|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|neuron fate commitment|homeostasis of number of cells within a tissue|positive regulation of phagocytosis|definitive hemopoiesis|semicircular canal development|negative regulation of fat cell proliferation|GABAergic neuron differentiation|negative regulation of neural precursor cell proliferation|negative regulation of neural precursor cell proliferation|regulation of forebrain neuron differentiation|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|enhancer sequence-specific DNA binding|DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|C2H2 zinc finger domain binding|,10,0,0,10,0.1,0.0715,0,0,0,0.85,0,0,-1.1,1.7
ENSMUSG00000020721,HELZ,helicase with zinc finger domain,nucleus|membrane|,None,nucleotide binding|helicase activity|protein binding|ATP binding|hydrolase activity|poly(A) RNA binding|metal ion binding|,10,0.1,0.043,10,-0.1,0.0745,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000075528,AARSD1,alanyl-tRNA synthetase domain containing 1,nucleus|cytoplasm|,translation|alanyl-tRNA aminoacylation|regulation of translational fidelity|tRNA aminoacylation|,"nucleotide binding|aminoacyl-tRNA editing activity|Ser-tRNA(Ala) hydrolase activity|nucleic acid binding|alanine-tRNA ligase activity|protein binding|ATP binding|ligase activity, forming aminoacyl-tRNA and related compounds|metal ion binding|",10,0,0,10,0.1,0.117,0,0,0,0.85,0,0,-1.1,1.9
ENSMUSG00000028023,PITX2,paired-like homeodomain transcription factor 2,nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|patterning of blood vessels|vasculogenesis|in utero embryonic development|neuron migration|extraocular skeletal muscle development|atrioventricular valve development|cardiac neural crest cell migration involved in outflow tract morphogenesis|pulmonary myocardium development|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|determination of left/right symmetry|heart development|heart development|skeletal muscle tissue development|myoblast fusion|anatomical structure morphogenesis|organ morphogenesis|Wnt signaling pathway|subthalamic nucleus development|hypothalamus cell migration|pituitary gland development|lung development|regulation of cell migration|embryonic camera-type eye development|embryonic hindlimb morphogenesis|vascular smooth muscle cell differentiation|deltoid tuberosity development|deltoid tuberosity development|regulation of cell proliferation|odontogenesis|odontogenesis|camera-type eye development|positive regulation of DNA binding|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|spleen development|embryonic digestive tract morphogenesis|cardiac muscle tissue development|cardiac muscle cell differentiation|atrial cardiac muscle tissue morphogenesis|ventricular cardiac muscle cell development|digestive system development|ventricular septum morphogenesis|left lung morphogenesis|pulmonary vein morphogenesis|superior vena cava morphogenesis|endodermal digestive tract morphogenesis|iris morphogenesis|cell proliferation involved in outflow tract morphogenesis|left/right axis specification|positive regulation of myoblast proliferation|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|chromatin DNA binding|protein homodimerization activity|sequence-specific DNA binding|phosphoprotein binding|,10,0.3,0.052,10,0,0,0,0,0,0.85,0,0,-1,1.9
ENSMUSG00000029061,MMP23,matrix metallopeptidase 23,endoplasmic reticulum|membrane|integral component of membrane|extracellular matrix|,proteolysis|,metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.1,0.64,10,0,0,0,0,0,0.85,0,0,-1.4,1.5
ENSMUSG00000025402,NAB2,Ngfi-A binding protein 2,nucleus|,"endochondral ossification|transcription, DNA-templated|regulation of transcription, DNA-templated|Schwann cell differentiation|negative regulation of transcription from RNA polymerase III promoter|myelination|regulation of epidermis development|negative regulation of transcription, DNA-templated|",transcription factor binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000024548,SETBP1,SET binding protein 1,nucleus|,biological_process|,molecular_function|DNA binding|,10,-0.1,0.218,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000039342,ANKAR,ankyrin and armadillo repeat containing,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.156,10,0,0,0,0,0,0.85,0,0,-1.3,1.8
ENSMUSG00000028741,MRTO4,"MRT4, mRNA turnover 4, homolog (S. cerevisiae)",intracellular|nucleus|ribosome|ribonucleoprotein complex|nuclear membrane|,biological_process|ribosome biogenesis|,poly(A) RNA binding|,8,-0.1,0.068,9,0.4,1.06,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000033581,IGF2BP2,insulin-like growth factor 2 mRNA binding protein 2,nucleus|cytoplasm|cytoskeleton|,regulation of translation|transport|mRNA transport|,nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|mRNA 3'-UTR binding|poly(A) RNA binding|mRNA 5'-UTR binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.8,1.2
ENSMUSG00000028159,DAPP1,dual adaptor for phosphotyrosine and 3-phosphoinositides 1,cytoplasm|plasma membrane|phosphatidylinositol 3-kinase complex|membrane|,None,"phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol 3-kinase regulator activity|phosphatidylinositol-3,4-bisphosphate binding|",10,0,0,10,0.5,0.853,0,0,0,0.85,0,0,-0.8,1.9
ENSMUSG00000005043,SGSH,N-sulfoglucosamine sulfohydrolase (sulfamidase),lysosome|extracellular vesicular exosome|,heparan sulfate proteoglycan metabolic process|,protein binding|sulfuric ester hydrolase activity|sulfuric ester hydrolase activity|N-sulfoglucosamine sulfohydrolase activity|hydrolase activity|,10,0.2,0.227,10,0,0,0,0,0,0.85,0,0,-1.3,1.7
ENSMUSG00000026934,LHX3,LIM homeobox protein 3,intracellular|nucleus|transcription factor complex|,"placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|motor neuron axon guidance|dorsal/ventral pattern formation|spinal cord motor neuron cell fate specification|ventral spinal cord interneuron specification|medial motor column neuron differentiation|spinal cord association neuron differentiation|pituitary gland development|cell differentiation|negative regulation of apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription factor binding transcription factor activity|DNA binding|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.1,0.224,10,0.1,0.242,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000043903,GM22,predicted gene 22,cellular_component|,biological_process|,molecular_function|,9,-0.1,0.0158,9,0,0,0,0,0,0.85,0,0,-1.5,1.7
ENSMUSG00000032661,OAS3,2'-5' oligoadenylate synthetase 3,extracellular space|nucleus|cytoplasm|plasma membrane|,immune system process|immune response|response to virus|negative regulation of viral genome replication|innate immune response|defense response to virus|regulation of ribonuclease activity|,nucleotide binding|2'-5'-oligoadenylate synthetase activity|2'-5'-oligoadenylate synthetase activity|RNA binding|double-stranded RNA binding|double-stranded RNA binding|ATP binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,0,0,10,-0.3,0.329,0,0,0,0.85,0,0,-2,0.8
ENSMUSG00000025498,IRF7,interferon regulatory factor 7,nucleus|cytoplasm|,"immune system process|regulation of adaptive immune response|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|immunoglobulin mediated immune response|interferon-alpha production|interferon-beta production|positive regulation of interferon-alpha production|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|regulation of MyD88-dependent toll-like receptor signaling pathway|regulation of MyD88-independent toll-like receptor signaling pathway|innate immune response|regulation of innate immune response|type I interferon biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of type I interferon-mediated signaling pathway|",regulatory region DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,9,0.5,1.88,9,-0.7,1.2,0,0,0,0.85,0,0,-1.8,1.3
ENSMUSG00000025151,MAGED1,"melanoma antigen, family D, 1",chromatin|nucleus|cytoplasm|plasma membrane|membrane|protein complex|,"regulation of transcription from RNA polymerase II promoter|circadian regulation of gene expression|regulation of circadian rhythm|positive regulation of MAP kinase activity|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|rhythmic process|negative regulation of epithelial cell proliferation|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of apoptotic signaling pathway|",transcription coactivator activity|protein binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.5
ENSMUSG00000038895,ZFP653,zinc finger protein 653,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000049823,ZBTB12,zinc finger and BTB domain containing 12,cellular_component|nucleus|,biological_process|,molecular_function|metal ion binding|,10,0.2,1.2,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000024175,TEKT4,tektin 4,nucleus|cytoplasm|cytoskeleton|microtubule|cilium|cell projection|,cell projection organization|regulation of fertilization|,None,10,0.4,1.14,10,0,0,0,0,0,0.85,0,0,-0.9,2
ENSMUSG00000029016,CLCN6,chloride channel 6,lysosomal membrane|endosome|membrane|integral component of membrane|,transport|ion transport|chloride transport|response to mechanical stimulus|transmembrane transport|,nucleotide binding|ion channel activity|voltage-gated chloride channel activity|ATP binding|antiporter activity|adenyl nucleotide binding|,10,-0.1,0.202,10,-0.7,0.16,0,0,0,0.85,0,0,-2,0.8
ENSMUSG00000026497,MIXL1,Mix1 homeobox-like 1 (Xenopus laevis),nuclear chromatin|nucleus|,"endoderm formation|hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|gastrulation|endoderm development|heart development|hemopoiesis|cell differentiation|endodermal cell differentiation|cell migration involved in gastrulation|positive regulation of transcription from RNA polymerase II promoter|digestive tract development|negative regulation of hematopoietic progenitor cell differentiation|positive regulation of mesoderm development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|protein homodimerization activity|sequence-specific DNA binding|,10,0,0,10,0.1,0.00388,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000034889,CACTIN,"cactin, spliceosome C complex subunit",nucleus|spliceosomal complex|cytoplasm|extracellular vesicular exosome|catalytic step 2 spliceosome|,negative regulation of protein phosphorylation|immune system process|mRNA processing|multicellular organismal development|RNA splicing|negative regulation of lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|negative regulation of interferon-beta production|negative regulation of interleukin-8 production|negative regulation of tumor necrosis factor production|negative regulation of toll-like receptor signaling pathway|innate immune response|negative regulation of type I interferon-mediated signaling pathway|cellular response to lipopolysaccharide|cellular response to interleukin-1|cellular response to tumor necrosis factor|,poly(A) RNA binding|,10,-0.1,0.207,10,0.1,0.105,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000016487,PPFIBP1,"PTPRF interacting protein, binding protein 1 (liprin beta 1)",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.518,0,0,0,0.85,0,0,-1.8,1.2
ENSMUSG00000041936,AGRN,agrin,basement membrane|basement membrane|basal lamina|basal lamina|extracellular space|extracellular space|cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|cell junction|extracellular matrix|extracellular matrix|axonal growth cone|synapse|synapse|extracellular vesicular exosome|,regulation of protein phosphorylation|positive regulation of protein phosphorylation|plasma membrane organization|synaptic transmission|synaptic transmission|multicellular organismal development|synapse assembly|neuromuscular junction development|regulation of synaptic growth at neuromuscular junction|regulation of receptor activity|cell differentiation|positive regulation of protein binding|regulation of Rac GTPase activity|positive regulation of Rho GTPase activity|receptor clustering|receptor clustering|receptor clustering|receptor clustering|positive regulation of neuron apoptotic process|neurotransmitter receptor metabolic process|positive regulation of synaptic growth at neuromuscular junction|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein heterotetramerization|positive regulation of filopodium assembly|regulation of microtubule cytoskeleton organization|regulation of axon guidance|positive regulation of protein geranylgeranylation|,dystroglycan binding|calcium ion binding|protein binding|acetylcholine receptor regulator activity|chondroitin sulfate binding|BMP binding|heparan sulfate proteoglycan binding|transforming growth factor beta binding|,10,0,0,10,-0.1,0.0974,0,0,0,0.85,0,0,-1.7,1.2
ENSMUSG00000067441,GM14920,predicted pseudogene 14920,nucleosome|nucleus|chromosome|,None,DNA binding|,10,0,0,10,-0.3,1.01,0,0,0,0.85,0,0,-1.8,1
ENSMUSG00000095362,GM14325,predicted gene 14325,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,-0.1,0.0768,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000047123,TICAM1,toll-like receptor adaptor molecule 1,ripoptosome|,macrophage activation involved in immune response|immune system process|MyD88-independent toll-like receptor signaling pathway|apoptotic process|inflammatory response|signal transduction|positive regulation of B cell proliferation|positive regulation of protein ubiquitination|lipopolysaccharide-mediated signaling pathway|positive regulation of protein binding|positive regulation of type I interferon production|response to lipopolysaccharide|response to lipopolysaccharide|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of natural killer cell activation|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|response to exogenous dsRNA|response to exogenous dsRNA|response to exogenous dsRNA|regulation of protein homodimerization activity|positive regulation of chemokine biosynthetic process|positive regulation of chemokine biosynthetic process|innate immune response|positive regulation of interferon-beta biosynthetic process|positive regulation of nitric oxide biosynthetic process|positive regulation of B cell activation|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|defense response to virus|apoptotic signaling pathway|,signal transducer activity|protein binding|protein kinase binding|,10,-0.1,0.26,10,0,0,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000007812,ZFP655,zinc finger protein 655,nucleus|nucleolus|cytoplasm|,"regulation of transcription, DNA-templated|negative regulation of G1/S transition of mitotic cell cycle|",sequence-specific DNA binding transcription factor activity|,10,0.1,0.13,10,-0.2,0.337,0,0,0,0.85,0,0,-1.4,1.5
ENSMUSG00000033730,EGR3,early growth response 3,nucleus|cytoplasm|,"positive regulation of endothelial cell proliferation|cell migration involved in sprouting angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|neuromuscular synaptic transmission|peripheral nervous system development|positive regulation of T cell differentiation in thymus|endothelial cell chemotaxis|cellular response to vascular endothelial growth factor stimulus|negative regulation of apoptotic process|negative regulation of apoptotic process|cellular response to fibroblast growth factor stimulus|regulation of gamma-delta T cell differentiation|cellular response to cAMP|cellular response to gonadotropin stimulus|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.207,10,0,0,0,0,0,0.85,0,0,-2,0.8
ENSMUSG00000070990,FOXE1,forkhead box E1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|thyroid hormone generation|cell migration|thyroid gland development|thyroid gland development|hair follicle morphogenesis|positive regulation of transcription, DNA-templated|embryonic organ morphogenesis|hard palate development|soft palate development|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.3,0.211,10,0,0,0,0,0,0.85,0,0,-1.8,1.1
ENSMUSG00000044243,BHLHA9,"basic helix-loop-helix family, member a9",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|",DNA binding|protein dimerization activity|,10,0,0,10,-0.1,0.132,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000042320,PROX2,prospero homeobox 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|",DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000020656,GRHL1,grainyhead-like 1 (Drosophila),nucleus|cytoplasm|Golgi apparatus|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.2,0.498,10,0,0,0,0,0,0.85,0,0,-1.5,1.4
ENSMUSG00000014704,HOXA2,homeobox A2,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|cell fate determination|osteoblast development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|segment specification|pattern specification process|motor neuron axon guidance|anterior/posterior pattern specification|dorsal/ventral pattern formation|dorsal/ventral pattern formation|rhombomere 2 development|rhombomere 3 development|rhombomere 3 morphogenesis|brain segmentation|middle ear morphogenesis|middle ear morphogenesis|cell fate commitment|negative regulation of neuron differentiation|negative regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|embryonic viscerocranium morphogenesis|embryonic skeletal system morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.1,0.0644,10,-0.2,0.597,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000025352,GDF11,growth differentiation factor 11,extracellular region|extracellular space|protein complex|,skeletal system development|metanephros development|ureteric bud development|negative regulation of cell proliferation|organ morphogenesis|anterior/posterior pattern specification|spinal cord anterior/posterior patterning|pancreas development|growth|negative regulation of cell differentiation|negative regulation of neuron differentiation|cell maturation|camera-type eye morphogenesis|palate development|,cytokine activity|protein binding|growth factor activity|,10,0.6,0.819,10,0,0,0,0,0,0.85,0,0,-0.7,2
ENSMUSG00000091519,SKOR2,SKI family transcriptional corepressor 2,nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|cerebellum morphogenesis|cerebellar Purkinje cell differentiation|regulation of cerebellar granule cell precursor proliferation|negative regulation of BMP signaling pathway|positive regulation of smoothened signaling pathway|regulation of dendrite morphogenesis|",transcription corepressor activity|histone deacetylase binding|SMAD binding|SMAD binding|,10,0,0,10,-1.3,2.47,0,0,0,0.85,0,0,-2,0.6
ENSMUSG00000078868,GM14412,N/A,None,None,None,6,0,0,7,0.7,0.466,0,0,0,0.85,0,0,-0.9,2
ENSMUSG00000021900,BTD,biotinidase,extracellular region|extracellular space|nucleolus|perikaryon|apical part of cell|extracellular vesicular exosome|,biotin metabolic process|nitrogen compound metabolic process|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|biotinidase activity|",10,-0.2,0.845,10,0.1,0.322,0,0,0,0.85,0,0,-1.5,1.4
ENSMUSG00000021007,SPATA7,spermatogenesis associated 7,cellular_component|,visual perception|biological_process|response to stimulus|,molecular_function|,10,-0.1,0.174,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000028134,PTBP2,polypyrimidine tract binding protein 2,nucleus|spliceosomal complex|,mRNA splice site selection|mRNA splice site selection|mRNA processing|RNA splicing|negative regulation of RNA splicing|regulation of neural precursor cell proliferation|,nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|protein binding|poly(A) RNA binding|,10,0.5,1.25,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000026077,NPAS2,neuronal PAS domain protein 2,nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|signal transduction|circadian regulation of gene expression|circadian sleep/wake cycle|regulation of circadian rhythm|locomotor rhythm|positive regulation of DNA repair|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|response to redox state|response to redox state|negative regulation of cell death|regulation of response to DNA damage stimulus|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|protein binding|metal ion binding|protein dimerization activity|Hsp90 protein binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000046982,TSHZ1,teashirt zinc finger family member 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|regulation of gene expression|middle ear morphogenesis|soft palate development|",DNA binding|protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000042570,MIER2,"mesoderm induction early response 1, family member 2",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|chromatin binding|,10,0.2,0.767,10,0,0,0,0,0,0.85,0,0,-1.3,1.5
ENSMUSG00000038331,SATB2,special AT-rich sequence binding protein 2,histone deacetylase complex|nuclear chromatin|nucleus|nucleus|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|neuron migration|osteoblast development|osteoblast development|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|embryonic pattern specification|regulation of gene expression|chromatin modification|commitment of neuronal cell to specific neuron type in forebrain|commitment of neuronal cell to specific neuron type in forebrain|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|cartilage development|palate development|cellular response to organic substance|",DNA binding|chromatin binding|protein binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.5
ENSMUSG00000001988,NPAS1,neuronal PAS domain protein 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|startle response|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|maternal behavior|",DNA binding|signal transducer activity|protein dimerization activity|,10,0,0,10,0.1,0.184,0,0,0,0.85,0,0,-1.2,1.8
ENSMUSG00000052040,KLF13,Kruppel-like factor 13,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of cell proliferation|negative regulation of erythrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.8,1.2
ENSMUSG00000025105,BNC1,basonuclin 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase I promoter|regulation of transcription from RNA polymerase II promoter|wound healing|positive regulation of epithelial cell proliferation|chromosome organization|",DNA binding|protein binding|metal ion binding|,10,-0.3,0.77,10,0,0,0,0,0,0.85,0,0,-1.7,1.2
ENSMUSG00000093661,EIF4E3,eukaryotic translation initiation factor 4E member 3,cellular_component|cytoplasm|,translation|translational initiation|regulation of translation|biological_process|,molecular_function|RNA binding|translation initiation factor activity|,4,0.4,0.112,4,0,0,0,0,0,0.85,0,0,-1.6,1.9
ENSMUSG00000032582,RBM6,RNA binding motif protein 6,nucleus|,None,poly(A) RNA binding|,10,0,0,10,-0.1,0.147,0,0,0,0.85,0,0,-1.8,1.2
ENSMUSG00000039759,THAP3,"THAP domain containing, apoptosis associated protein 3",cellular_component|,biological_process|,molecular_function|nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.2,1.8
ENSMUSG00000039354,SMARCAL1,"SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1",nucleus|DNA replication factor A complex|site of double-strand break|,DNA strand renaturation|ATP catabolic process|ATP catabolic process|DNA metabolic process|regulation of transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|chromatin modification|replication fork processing|,nucleotide binding|DNA binding|helicase activity|ATP binding|DNA-dependent ATPase activity|DNA-dependent ATPase activity|hydrolase activity|annealing helicase activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000030145,ZFP248,zinc finger protein 248,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.2,0.564,9,0,0,0,0,0,0.85,0,0,-1.7,1.2
ENSMUSG00000024695,ZFP91,zinc finger protein 91,nucleus|,activation of NF-kappaB-inducing kinase activity|protein K63-linked ubiquitination|,"nucleic acid binding|ubiquitin-protein transferase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.3,0.884,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000042589,CUX2,cut-like homeobox 2,nucleus|nucleus|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|short-term memory|positive regulation of gene expression|negative regulation of transcription, DNA-templated|positive regulation of dendrite morphogenesis|cognition|positive regulation of synapse assembly|positive regulation of dendritic spine morphogenesis|cellular response to organic substance|positive regulation of excitatory postsynaptic membrane potential|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding|,10,-0.3,0.114,10,0.1,0.0592,0,0,0,0.85,0,0,-1.6,1.2
ENSMUSG00000010505,MYT1,myelin transcription factor 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|cell differentiation|",enhancer sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|metal ion binding|,10,0.1,0.221,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000015579,NKX2-5,NK2 homeobox 5,nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|vasculogenesis|heart looping|heart morphogenesis|outflow tract septum morphogenesis|outflow tract morphogenesis|outflow tract morphogenesis|cardiac conduction system development|cardiac conduction system development|atrioventricular node development|bundle of His development|Purkinje myocyte differentiation|cardiac ventricle morphogenesis|cardiac ventricle formation|right ventricular cardiac muscle tissue morphogenesis|ventricular trabecula myocardium morphogenesis|apoptotic process involved in heart morphogenesis|septum secundum development|proepicardium development|pulmonary myocardium development|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|endoderm development|heart development|heart development|adult heart development|adult heart development|positive regulation of cell proliferation|positive regulation of gene expression|negative regulation of cardiac muscle cell apoptotic process|negative regulation of cardiac muscle cell apoptotic process|positive regulation of transcription via serum response element binding|positive regulation of sodium ion transport|negative regulation of myotube differentiation|hemopoiesis|cell differentiation|BMP signaling pathway|thyroid gland development|thyroid gland development|embryonic heart tube development|negative regulation of apoptotic process|tongue development|sarcomere organization|positive regulation of neuron differentiation|positive regulation of heart contraction|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|spleen development|spleen development|spleen development|cardiac muscle tissue development|positive regulation of cardioblast differentiation|ventricular cardiac myofibril assembly|cardiac muscle cell differentiation|cardiac muscle cell differentiation|cardiac muscle cell differentiation|cardiac muscle cell differentiation|cardiac muscle tissue morphogenesis|atrial cardiac muscle cell development|ventricular cardiac muscle cell development|regulation of cardiac muscle contraction|pharyngeal system development|cardiac muscle cell proliferation|regulation of cardiac muscle cell proliferation|heart contraction|cardiac muscle contraction|canonical Wnt signaling pathway|positive regulation of transcription initiation from RNA polymerase II promoter|heart trabecula formation|ventricular septum morphogenesis|atrial septum morphogenesis|atrioventricular node cell development|atrioventricular node cell fate commitment|embryonic heart tube left/right pattern formation|cardiovascular system development|negative regulation of canonical Wnt signaling pathway|positive regulation of voltage-gated calcium channel activity|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription cofactor activity|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|serum response element binding|protein homodimerization activity|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.5
ENSMUSG00000004328,HIF3A,"hypoxia inducible factor 3, alpha subunit",nucleus|nucleus|cytoplasm|,"response to hypoxia|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|signal transduction|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription corepressor activity|signal transducer activity|protein dimerization activity|,10,-0.1,0.225,10,0.1,0.183,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000048047,ZBTB33,zinc finger and BTB domain containing 33,nucleus|nucleus|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Wnt signaling pathway|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|protein binding|methyl-CpG binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000022515,ANKS3,ankyrin repeat and sterile alpha motif domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.6,0.559,0,0,0,0.85,0,0,-1,1.9
ENSMUSG00000071350,SETDB2,"SET domain, bifurcated 2",nucleus|chromosome|,cell cycle|chromosome segregation|mitotic nuclear division|multicellular organismal development|chromatin modification|peptidyl-lysine methylation|methylation|histone lysine methylation|cell division|histone H3-K9 methylation|,DNA binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|metal ion binding|histone methyltransferase activity (H3-K9 specific)|,9,-0.2,0.245,9,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000046709,MAPK10,mitogen-activated protein kinase 10,intracellular|nucleus|cytoplasm|mitochondrion|plasma membrane|membrane|,protein phosphorylation|JNK cascade|JNK cascade|JUN phosphorylation|JUN phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|JUN kinase activity|JUN kinase activity|MAP kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0.1,0.486,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000023050,MAP3K12,mitogen-activated protein kinase kinase kinase 12,cytoplasm|cytosol|plasma membrane|membrane|axon|growth cone|,activation of MAPKK activity|protein phosphorylation|protein phosphorylation|JNK cascade|phosphorylation|histone phosphorylation|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein homodimerization activity|",10,0,0,10,-0.1,0.196,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000057842,ZFP595,zinc finger protein 595,cellular_component|,biological_process|,molecular_function|metal ion binding|,9,-0.1,0.113,9,0.1,0.0997,0,0,0,0.85,0,0,-1.4,1.7
ENSMUSG00000022485,HOXC5,homeobox C5,nucleus|cell junction|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|embryonic skeletal system development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.2,1.8
ENSMUSG00000029423,PIWIL1,piwi-like RNA-mediated gene silencing 1,cytoplasm|polysome|mRNA cap binding complex|chromatoid body|,regulation of translation|meiotic nuclear division|multicellular organismal development|spermatogenesis|spermatid development|cell differentiation|gene silencing by RNA|piRNA metabolic process|,nucleic acid binding|RNA binding|single-stranded RNA binding|mRNA binding|protein binding|protein kinase binding|piRNA binding|,10,0,0,10,-0.1,0.73,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000031808,SLC27A1,"solute carrier family 27 (fatty acid transporter), member 1",cytoplasm|mitochondrion|mitochondrial inner membrane|endoplasmic reticulum|plasma membrane|plasma membrane|plasma membrane|caveola|membrane|membrane|integral component of membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|,medium-chain fatty acid transport|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|phosphatidylethanolamine biosynthetic process|phosphatidic acid biosynthetic process|phosphatidylglycerol biosynthetic process|phosphatidylcholine biosynthetic process|phosphatidylserine biosynthetic process|phosphatidylinositol biosynthetic process|transport|lipid transport|metabolic process|response to cold|fatty acid transport|fatty acid transport|long-chain fatty acid transport|positive regulation of heat generation|cardiolipin biosynthetic process|response to insulin|adiponectin-activated signaling pathway|negative regulation of phospholipid biosynthetic process|positive regulation of protein serine/threonine kinase activity|,"nucleotide binding|catalytic activity|acyl-CoA ligase activity|long-chain fatty acid-CoA ligase activity|succinate-CoA ligase activity|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity|fatty acid transporter activity|fatty acid transporter activity|fatty acid ligase activity|ligase activity|3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity|benzoyl acetate-CoA ligase activity|2,4-dichlorobenzoate-CoA ligase activity|very long-chain fatty acid-CoA ligase activity|pivalate-CoA ligase activity|cyclopropanecarboxylate-CoA ligase activity|adipate-CoA ligase activity|citronellyl-CoA ligase activity|mentha-1,3-dione-CoA ligase activity|thiophene-2-carboxylate-CoA ligase activity|2,4,4-trimethylpentanoate-CoA ligase activity|cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|protein homodimerization activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity|3-hydroxypropionyl-CoA synthetase activity|perillic acid:CoA ligase (ADP-forming) activity|perillic acid:CoA ligase (AMP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity|pristanate-CoA ligase activity|malonyl-CoA synthetase activity|",10,0.1,0.17,10,0,0,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000005503,EVX1,even skipped homeotic gene 1 homolog,nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|embryo development ending in birth or egg hatching|regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding|,10,0,0,10,-0.1,0.0691,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000085111,ASCL4,achaete-scute complex homolog 4 (Drosophila),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.3,1.7
ENSMUSG00000044149,NKRF,NF-kappaB repressing factor,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|poly(A) RNA binding|,9,-0.1,0.179,9,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000038797,ZSCAN2,zinc finger and SCAN domain containing 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|cell differentiation|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.0107,10,1.2,1.3,0,0,0,0.85,0,0,-0.7,2
ENSMUSG00000047909,ANKRD16,ankyrin repeat domain 16,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.072,10,0,0,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000031586,RBPMS,RNA binding protein gene with multiple splicing,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of SMAD protein import into nucleus|regulation of RNA biosynthetic process|",nucleotide binding|nucleic acid binding|transcription coactivator activity|RNA binding|poly(A) binding|poly(A) RNA binding|,10,-0.9,0.737,10,0,0,0,0,0,0.85,0,0,-2,0.8
ENSMUSG00000001158,SNRNP27,small nuclear ribonucleoprotein 27 (U4/U6.U5),cellular_component|nucleus|,mRNA processing|biological_process|RNA splicing|,molecular_function|,10,0,0,10,0.4,1.45,0,0,0,0.85,0,0,-0.7,1.9
ENSMUSG00000049577,ZFPM1,"zinc finger protein, multitype 1",nucleus|transcription factor complex|cytoplasm|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|outflow tract morphogenesis|atrioventricular valve morphogenesis|mitral valve formation|tricuspid valve formation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|heart development|regulation of definitive erythrocyte differentiation|erythrocyte differentiation|erythrocyte differentiation|megakaryocyte differentiation|megakaryocyte differentiation|platelet formation|granulocyte differentiation|negative regulation of protein binding|regulation of chemokine production|embryonic hemopoiesis|megakaryocyte development|positive regulation of interferon-gamma biosynthetic process|negative regulation of interleukin-4 biosynthetic process|negative regulation of fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|homeostasis of number of cells|cardiac muscle tissue morphogenesis|definitive erythrocyte differentiation|primitive erythrocyte differentiation|negative regulation of mast cell differentiation|ventricular septum morphogenesis|atrial septum morphogenesis|transcriptional activation by promoter-enhancer looping|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription factor binding|RNA polymerase II activating transcription factor binding|nucleic acid binding|DNA binding|transcription corepressor activity|protein binding|transcription factor binding|metal ion binding|,10,0.3,0.997,10,-0.1,0.077,0,0,0,0.85,0,0,-1.1,1.7
ENSMUSG00000049536,TCEAL1,transcription elongation factor A (SII)-like 1,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",protein binding|,10,0,0,10,-0.2,0.405,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000036721,ZSCAN12,zinc finger and SCAN domain containing 12,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.872,10,0,0,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000020831,0610010K14RIK,RIKEN cDNA 0610010K14 gene,nucleus|NURF complex|MLL1 complex|,biological_process|chromatin modification|,molecular_function|DNA binding|chromatin binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000074194,ZFP791,zinc finger protein 791,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.013,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000035916,PTPRQ,"protein tyrosine phosphatase, receptor type, Q",membrane|integral component of membrane|stereocilium bundle|,hematopoietic progenitor cell differentiation|protein dephosphorylation|dephosphorylation|inner ear morphogenesis|regulation of fat cell differentiation|neuromuscular process controlling balance|detection of mechanical stimulus involved in sensory perception of sound|vestibular receptor cell morphogenesis|,"phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0,0,10,0.2,0.613,0,0,0,0.85,0,0,-1.5,1.4
ENSMUSG00000044220,NKX2-3,NK2 homeobox 3,nucleus|,"leukocyte homeostasis|plasma cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|triglyceride metabolic process|immune response|multicellular organismal development|post-embryonic development|gland morphogenesis|B cell differentiation|macrophage differentiation|regulation of cell proliferation|odontogenesis of dentin-containing tooth|CD4-positive, alpha-beta T cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|lymph node development|spleen development|mucosal-associated lymphoid tissue development|Peyer's patch development|digestive tract development|post-embryonic digestive tract morphogenesis|leukocyte migration|",DNA binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.5
ENSMUSG00000020086,H2AFY2,"H2A histone family, member Y2",nucleosome|nuclear chromatin|Barr body|nucleus|chromosome|ESC/E(Z) complex|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|nucleosome assembly|brain development|dosage compensation|chromatin modification|negative regulation of gene expression, epigenetic|establishment of protein localization to chromatin|negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|",DNA binding|chromatin DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0.3,0.00397,10,0,0,0,0,0,0.85,0,0,-2,1.1
ENSMUSG00000021911,PARG,poly (ADP-ribose) glycohydrolase,chromatin|nucleus|nucleus|cytosol|intracellular membrane-bounded organelle|,carbohydrate metabolic process|cellular response to DNA damage stimulus|metabolic process|detection of bacterium|positive regulation of DNA repair|,"chromatin binding|poly(ADP-ribose) glycohydrolase activity|poly(ADP-ribose) glycohydrolase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.1,0.186,10,-0.2,0.831,0,0,0,0.85,0,0,-1.6,1.3
ENSMUSG00000083616,H2AFB3,"H2A histone family, member B3",nucleosome|nuclear nucleosome|nucleus|chromosome|transcriptionally active chromatin|,None,DNA binding|,10,0.1,0.00193,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000062519,ZFP398,zinc finger protein 398,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.2,1.7
ENSMUSG00000033863,KLF9,Kruppel-like factor 9,nucleus|nucleus|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|embryo implantation|positive regulation of transcription from RNA polymerase II promoter|progesterone receptor signaling pathway|cellular response to thyroid hormone stimulus|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|metal ion binding|,9,0.2,0.233,9,-0.9,1.42,0,0,0,0.85,0,0,-2,1
ENSMUSG00000048001,HES5,hairy and enhancer of split 5 (Drosophila),nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|protein complex assembly|cell adhesion|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|Notch signaling pathway|smoothened signaling pathway|multicellular organismal development|nervous system development|brain development|positive regulation of cell proliferation|oligodendrocyte development|telencephalon development|glial cell fate commitment|forebrain radial glial cell differentiation|neural tube development|central nervous system myelination|cell differentiation|positive regulation of BMP signaling pathway|regulation of myelination|auditory receptor cell differentiation|positive regulation of tyrosine phosphorylation of Stat3 protein|auditory receptor cell fate determination|camera-type eye development|regulation of cell differentiation|negative regulation of neuron differentiation|negative regulation of neuron differentiation|positive regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JAK-STAT cascade|cell maturation|positive regulation of smooth muscle cell proliferation|astrocyte differentiation|negative regulation of astrocyte differentiation|negative regulation of oligodendrocyte differentiation|negative regulation of oligodendrocyte differentiation|regulation of neurogenesis|cartilage development|cartilage development|neuronal stem cell maintenance|neuronal stem cell maintenance|negative regulation of stem cell differentiation|negative regulation of pro-B cell differentiation|negative regulation of forebrain neuron differentiation|negative regulation of inner ear receptor cell differentiation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|double-stranded DNA binding|protein binding|transcription factor binding|protein dimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000073423,ZFP414,zinc finger protein 414,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.3,1.7
ENSMUSG00000021067,SAV1,salvador homolog 1 (Drosophila),intracellular|nucleus|cytoplasm|,hair follicle development|signal transduction|keratinocyte differentiation|keratinocyte differentiation|hippo signaling|hippo signaling|positive regulation of apoptotic process|regulation of organ growth|negative regulation of epithelial cell proliferation|negative regulation of cardiac muscle cell proliferation|ventricular septum morphogenesis|lung epithelial cell differentiation|intestinal epithelial cell differentiation|regulation of stem cell maintenance|,None,10,0.3,0.421,10,-0.2,0.45,0,0,0,0.85,0,0,-1.2,1.6
ENSMUSG00000070330,TMEM235,transmembrane protein 235,cytoplasm|endoplasmic reticulum|tight junction|membrane|integral component of membrane|apical plasma membrane|,biological_process|,molecular_function|structural molecule activity|,10,0,0,10,0.1,0.036,0,0,0,0.85,0,0,-1,2
ENSMUSG00000035877,ZHX3,zinc fingers and homeoboxes 3,nucleus|nucleus|cell cortex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|cell differentiation|positive regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000045268,ZFP691,zinc finger protein 691,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000043432,LENG9,leukocyte receptor cluster (LRC) member 9,cellular_component|,biological_process|,molecular_function|catalytic activity|metal ion binding|,10,1,1.71,10,0,0,0,0,0,0.85,0,0,-0.7,2
ENSMUSG00000025586,CPEB1,cytoplasmic polyadenylation element binding protein 1,nucleus|cytoplasm|plasma membrane|membrane|cell junction|ribonucleoprotein complex|synapse|postsynaptic membrane|meiotic spindle|,mRNA processing|regulation of translation|synaptonemal complex assembly|cellular response to insulin stimulus|regulation of neuronal synaptic plasticity|cellular response to amino acid stimulus|cellular response to hypoxia|cellular response to hypoxia|negative regulation of cytoplasmic translation|negative regulation of cytoplasmic translation|,"nucleotide binding|translation repressor activity, nucleic acid binding|nucleic acid binding|RNA binding|mRNA binding|protein binding|mRNA 3'-UTR AU-rich region binding|metal ion binding|",10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000069867,PABPN1L,poly(A)binding protein nuclear 1-like,cytoplasm|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000059851,SUV420H2,suppressor of variegation 4-20 homolog 2 (Drosophila),"condensed nuclear chromosome, centromeric region|nucleus|chromosome|nuclear heterochromatin|","transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone methylation|peptidyl-lysine methylation|methylation|histone H4-K20 methylation|histone H4-K20 trimethylation|",methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H4-K20 specific)|,10,0.1,0.00117,10,0,0,0,0,0,0.85,0,0,-1.3,1.7
ENSMUSG00000045314,SOWAHB,sosondowah ankyrin repeat domain family member B,cellular_component|,biological_process|,molecular_function|,9,0.9,0.888,9,0,0,0,0,0,0.85,0,0,-0.8,2
ENSMUSG00000023991,FOXP4,forkhead box P4,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|heart development|embryonic foregut morphogenesis|lung secretory cell differentiation|regulation of lung goblet cell differentiation|negative regulation of lung goblet cell differentiation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,0.1,0.12,10,0,0,0,0,0,0.85,0,0,-1.7,1.2
ENSMUSG00000038415,FOXQ1,forkhead box Q1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|hair follicle morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,5,0.7,1.06,5,0,0,0,0,0,0.85,0,0,-1.2,2
ENSMUSG00000074220,ZFP382,zinc finger protein 382,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,0.2,0.957,10,0,0,0,0,0,0.85,0,0,-0.9,2
ENSMUSG00000046518,FERD3L,Fer3-like (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|floor plate development|negative regulation of transcription, DNA-templated|cell development|regulation of neurogenesis|",DNA binding|protein dimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000020542,MYOCD,myocardin,nucleus|nucleus|SRF-myogenin-E12 complex|,"negative regulation of transcription from RNA polymerase II promoter|regulation of cell growth by extracellular stimulus|vasculogenesis|cardiac ventricle development|positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|heart development|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cardiac muscle cell apoptotic process|negative regulation of myotube differentiation|positive regulation of transforming growth factor beta receptor signaling pathway|regulation of histone acetylation|hepatic stellate cell activation|muscle cell differentiation|positive regulation of DNA binding|cellular component maintenance|regulation of myoblast differentiation|negative regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle contraction|lung alveolus development|digestive tract development|positive regulation of sequence-specific DNA binding transcription factor activity|smooth muscle cell differentiation|smooth muscle cell differentiation|regulation of smooth muscle cell differentiation|positive regulation of smooth muscle cell differentiation|cardiac muscle cell differentiation|ventricular cardiac muscle cell differentiation|uterus development|urinary bladder development|cell growth involved in cardiac muscle cell development|ductus arteriosus closure|negative regulation of beta-amyloid clearance|positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|positive regulation of cardiac vascular smooth muscle cell differentiation|positive regulation of cardiac muscle cell differentiation|negative regulation of skeletal muscle cell differentiation|",core promoter sequence-specific DNA binding|RNA polymerase II transcription factor binding transcription factor activity|RNA polymerase II transcription factor binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|transcription coactivator activity|protein binding|transcription factor binding|protein domain specific binding|histone acetyltransferase binding|histone deacetylase binding|R-SMAD binding|,9,0,0,9,-0.3,0.706,0,0,0,0.85,0,0,-1.8,1.1
ENSMUSG00000048728,ZFP454,zinc finger protein 454,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.1,0.0596,0,0,0,0.85,0,0,-1.4,1.6
ENSMUSG00000048562,SP8,trans-acting transcription factor 8,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|dorsal/ventral pattern formation|proximal/distal pattern formation|embryonic limb morphogenesis|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.1,0.288,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000006050,SRA1,steroid receptor RNA activator 1,nucleus|nucleus|transcription factor complex|cytoplasm|steroid hormone aporeceptor complex|plasma membrane|microtubule cytoskeleton|ribonucleoprotein complex|cell leading edge|intercellular bridge|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|apoptotic process|cell proliferation|cell differentiation|regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of receptor activity|",DNA binding|transcription cofactor activity|transcription coactivator activity|thyroid hormone receptor activator activity|ligand-dependent nuclear receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity|,10,0,0,10,0.1,0.125,0,0,0,0.85,0,0,-1.5,1.5
ENSMUSG00000059246,FOXB1,forkhead box B1,nucleus|,"somitogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|axon target recognition|lactation|visual learning|mammillary body development|hypothalamus cell migration|telencephalon cell migration|midbrain development|floor plate development|negative regulation of neuron apoptotic process|epithelial cell differentiation involved in mammary gland alveolus development|mammillothalamic axonal tract development|mammary gland lobule development|inferior colliculus development|cell migration in diencephalon|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.2,1.1,10,0,0,0,0,0,0.85,0,0,-1.1,1.8
ENSMUSG00000045519,ZFP560,zinc finger protein 560,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.2,0.124,10,0,0,0,0,0,0.85,0,0,-1.3,1.7
ENSMUSG00000034266,BATF,"basic leucine zipper transcription factor, ATF-like",intracellular|nucleus|cytoplasm|,"cytokine production|lymphoid progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell differentiation|DNA damage response, signal transduction by p53 class mediator|defense response to protozoan|myeloid dendritic cell differentiation|T-helper 2 cell differentiation|isotype switching|hematopoietic stem cell differentiation|T-helper 17 cell differentiation|T-helper 17 cell lineage commitment|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.5,1.6
ENSMUSG00000019230,LHX9,LIM homeobox protein 9,nucleus|,"regulation of transcription, DNA-templated|cell proliferation|male gonad development|female gonad development|gonad morphogenesis|",DNA binding|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,9,-0.1,0.0321,9,0.1,0.124,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000036211,HIST1H1T,"histone cluster 1, H1t",nucleosome|condensed nuclear chromosome|intracellular|nucleus|chromosome|,nucleosome assembly|multicellular organismal development|spermatogenesis|binding of sperm to zona pellucida|cell differentiation|sperm motility|,DNA binding|,10,-0.2,0.117,10,0,0,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000025128,BHLHE22,"basic helix-loop-helix family, member e22",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|corpus callosum morphogenesis|cerebral cortex regionalization|central nervous system projection neuron axonogenesis|corticospinal tract morphogenesis|corticospinal tract morphogenesis|anterior commissure morphogenesis|neuron differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|retinal bipolar neuron differentiation|retina morphogenesis in camera-type eye|",sequence-specific DNA binding RNA polymerase II transcription factor activity|chromatin binding|protein binding|protein homodimerization activity|protein dimerization activity|,10,-0.1,0.164,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000072770,ACRBP,proacrosin binding protein,acrosomal vesicle|extracellular region|nucleus|cytoplasmic vesicle|,spermatid development|positive regulation of peptidase activity|,peptidase activator activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-0.8,2
ENSMUSG00000029644,PDX1,pancreatic and duodenal homeobox 1,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|liver development|type B pancreatic cell differentiation|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|smoothened signaling pathway|nitric oxide mediated signal transduction|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|response to glucose|positive regulation of cell death|morphogenesis of embryonic epithelium|insulin secretion|cell differentiation|cell differentiation|pancreas development|exocrine pancreas development|endocrine pancreas development|positive regulation of insulin secretion|regulation of cell proliferation|glucose homeostasis|glucose homeostasis|glucose homeostasis|positive regulation of DNA binding|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|digestive tract development|stem cell differentiation|detection of glucose|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of type B pancreatic cell apoptotic process|",core promoter sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein complex binding|sequence-specific DNA binding|sequence-specific DNA binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.6,1.4
ENSMUSG00000048763,HOXB3,homeobox B3,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|rhombomere development|glossopharyngeal nerve morphogenesis|thyroid gland development|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|regulation of neurogenesis|cartilage development|definitive hemopoiesis|face development|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.85,0,0,-1.7,1.4
ENSMUSG00000074519,ETOHI1,ethanol induced 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.335,10,0.1,0.124,0,0,0,0.85,0,0,-1.7,1.3
ENSMUSG00000039621,PREX1,"phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1",cytoplasm|cytosol|plasma membrane|membrane|growth cone|dendritic shaft|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,G-protein coupled receptor signaling pathway|T cell differentiation|neutrophil chemotaxis|regulation of actin filament polymerization|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of cell adhesion|regulation of dendrite development|reactive oxygen species metabolic process|positive regulation of substrate adhesion-dependent cell spreading|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|phospholipid binding|,10,3.1,161,10,3.2,202,3.2,362,362,1.00E-05,1,1,2.8,3.8
ENSMUSG00000053436,MAPK14,mitogen-activated protein kinase 14,spindle pole|cell|nucleus|nucleus|cytoplasm|mitochondrion|cytosol|cytosol|extracellular vesicular exosome|,"DNA damage checkpoint|cell morphogenesis|cartilage condensation|angiogenesis|chondrocyte differentiation|chondrocyte differentiation|glucose metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|response to stress|cellular response to DNA damage stimulus|transmembrane receptor protein serine/threonine kinase signaling pathway|skeletal muscle tissue development|positive regulation of myotube differentiation|myoblast differentiation involved in skeletal muscle regeneration|phosphorylation|peptidyl-serine phosphorylation|fatty acid oxidation|osteoclast differentiation|lipopolysaccharide-mediated signaling pathway|response to muramyl dipeptide|response to lipopolysaccharide|intracellular signal transduction|intracellular signal transduction|cellular response to vascular endothelial growth factor stimulus|p38MAPK cascade|positive regulation of protein import into nucleus|signal transduction in response to DNA damage|positive regulation of erythrocyte differentiation|positive regulation of myoblast differentiation|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|vascular endothelial growth factor receptor signaling pathway|striated muscle cell differentiation|stress-activated MAPK cascade|cellular response to lipopolysaccharide|cellular response to ionizing radiation|negative regulation of canonical Wnt signaling pathway|stress-induced premature senescence|positive regulation of myoblast fusion|positive regulation of reactive oxygen species metabolic process|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|MAP kinase activity|protein binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|NFAT protein binding|",10,1.6,125,10,1.9,106,1.8,230,230,1.00E-05,1,1,1.6,2.3
ENSMUSG00000002968,MED25,mediator complex subunit 25,cellular_component|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of chromatin binding|positive regulation of transcription from RNA polymerase II promoter|negative regulation of fibroblast proliferation|positive regulation of cell cycle arrest|positive regulation of mediator complex assembly|",transcription factor binding|retinoic acid receptor binding|retinoic acid receptor binding|retinoid X receptor binding|retinoid X receptor binding|,10,1.6,107,10,1.9,52.3,1.7,158,158,1.00E-05,1,1,1.4,2.2
ENSMUSG00000051495,IRF2BP2,interferon regulatory factor 2 binding protein 2,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",transcription corepressor activity|metal ion binding|,10,-1.8,56.6,10,-0.9,21.8,-1.4,73.5,-73.5,1.00E-05,1,1,-2.1,-1
ENSMUSG00000021264,YY1,YY1 transcription factor,nucleus|nucleus|transcription factor complex|transcription factor complex|Ino80 complex|PcG protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|double-strand break repair via homologous recombination|DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|RNA localization|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|spermatogenesis|anterior/posterior pattern specification|anterior/posterior pattern specification|response to UV-C|response to UV-C|cell differentiation|cellular response to UV|camera-type eye morphogenesis|chromosome organization|",four-way junction DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA binding|protein binding|transcription regulatory region DNA binding|metal ion binding|,9,1.5,59.5,10,0.8,10.3,1.3,66.7,66.7,1.00E-05,1,1,0.9,2
ENSMUSG00000038002,CRAMP1L,"Crm, cramped-like (Drosophila)",cellular_component|nucleus|,biological_process|,molecular_function|DNA binding|chromatin binding|,10,1,32.9,10,1.3,34.5,1.2,65.9,65.9,1.00E-05,1,1,0.9,1.7
ENSMUSG00000026074,MAP4K4,mitogen-activated protein kinase kinase kinase kinase 4,intracellular|cytoplasm|,protein phosphorylation|protein phosphorylation|protein phosphorylation|response to stress|negative regulation of neuron projection development|phosphorylation|signal transduction by phosphorylation|intracellular signal transduction|intracellular signal transduction|intracellular signal transduction|regulation of JNK cascade|negative regulation of insulin secretion involved in cellular response to glucose stimulus|negative regulation of neuron projection regeneration|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,1,24.2,10,1.2,38.7,1.1,62.1,62.1,6.00E-05,1,1,0.8,1.5
ENSMUSG00000029196,TADA2B,transcriptional adaptor 2B,nucleus|STAGA complex|SAGA-type complex|,biological_process|,protein binding|,10,1.5,46.3,10,1,15.8,1.3,60.9,60.9,7.00E-05,1,1,0.9,2
ENSMUSG00000005150,WDR83,WD repeat domain containing 83,nucleus|spliceosomal complex|cytoplasm|catalytic step 2 spliceosome|,"RNA splicing, via transesterification reactions|mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",molecular_function|,10,1.6,10.4,10,1.6,42.4,1.6,52.4,52.4,0.00018,1,1,1.1,2.3
ENSMUSG00000035575,UTP6,"UTP6, small subunit (SSU) processome component, homolog (yeast)",intracellular|nucleus|nucleolus|,rRNA processing|RNA processing|,None,10,-1.8,51,10,-0.4,2.13,-1.8,49.2,-49.2,0.0004,1,1,-2.9,-1.2
ENSMUSG00000019494,COPS6,"COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)",nucleus|cytoplasm|COP9 signalosome|COP9 signalosome|extracellular vesicular exosome|,cullin deneddylation|,protein binding|,9,0.8,7.04,10,1.4,43.5,1.2,48.1,48.1,0.00047,1,1,0.9,1.9
ENSMUSG00000028540,DPH2,DPH2 homolog (S. cerevisiae),cellular_component|cytoplasm|,peptidyl-diphthamide biosynthetic process from peptidyl-histidine|,protein binding|,10,0.9,30.2,10,0.7,17.1,0.8,46.5,46.5,0.00063,1,1,0.6,1.3
ENSMUSG00000032301,PSMA4,"proteasome (prosome, macropain) subunit, alpha type 4","proteasome complex|cytoplasmic mRNA processing body|nucleus|cytoplasm|proteasome core complex|proteasome core complex, alpha-subunit complex|extracellular vesicular exosome|",proteolysis|ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,10,-1.5,39.9,8,-1.1,8.29,-1.4,46.1,-46.1,0.00065,1,1,-2.5,-0.9
ENSMUSG00000040782,RFWD2,ring finger and WD repeat domain 2,Golgi membrane|nucleus|cytoplasm|centrosome|focal adhesion|,None,"protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.8,31.9,10,0.7,14.2,0.8,45.6,45.6,0.00068,1,1,0.5,1.3
ENSMUSG00000047388,ATMIN,ATM interactor,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",transcription regulatory region DNA binding|dynein binding|metal ion binding|,10,0.6,26.6,10,0.7,19.1,0.7,45.2,45.2,0.00072,1,1,0.5,1.2
ENSMUSG00000026799,MED27,mediator complex subunit 27,nucleus|transcription factor complex|nucleolus|cytoplasm|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|stem cell maintenance|",transcription coactivator activity|,10,-1.9,23.1,10,-2.2,22.3,-2.1,44.7,-44.7,0.00078,1,1,-3.9,-1.6
ENSMUSG00000051510,MAFG,"v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)",nucleus|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|adult behavior|regulation of cellular pH|regulation of cell proliferation|regulation of epidermal cell differentiation|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|protein heterodimerization activity|,9,1.4,31.6,10,1.2,12.8,1.3,44,44,0.00085,1,1,0.9,2.2
ENSMUSG00000038705,GMEB2,glucocorticoid modulatory element binding protein 2,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|transcription coactivator activity|metal ion binding|,10,1.1,18,10,1.1,26,1.1,43.6,43.6,0.00092,1,1,0.8,1.8
ENSMUSG00000028042,ZBTB7B,zinc finger and BTB domain containing 7B,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of gene expression|cell differentiation|regulation of CD4-positive, alpha-beta T cell differentiation|regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|metal ion binding|,10,0.9,25.4,10,1,16.5,1,41.3,41.3,0.00133,0,1,0.7,1.5
ENSMUSG00000033237,ARID2,"AT rich interactive domain 2 (ARID, RFX-like)",nucleus|transcription factor complex|,nucleosome disassembly|positive regulation of transcription from RNA polymerase II promoter|,transcription factor binding|,10,-1.4,29.2,9,-1.2,11.2,-1.3,39.8,-39.8,0.00166,0,1,-2.1,-0.8
ENSMUSG00000037857,NUFIP2,nuclear fragile X mental retardation protein interacting protein 2,nucleus|cytoplasm|membrane|polysomal ribosome|,None,RNA binding|poly(A) RNA binding|,10,1,18.1,10,1,21.8,1,39.5,39.5,0.00172,0,1,0.7,1.7
ENSMUSG00000025025,MXI1,Max interacting protein 1,nucleus|nucleus|nucleolus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|protein binding|protein dimerization activity|,10,1,26.6,10,0.6,12.3,0.8,37.4,37.4,0.00219,0,1,0.5,1.4
ENSMUSG00000039238,ZFP750,zinc finger protein 750,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|epidermis development|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|metal ion binding|,9,-0.9,12.9,9,-1.8,25.8,-1.6,36,-36,0.00265,0,0,-2.5,-0.7
ENSMUSG00000002524,PUF60,poly-U binding splicing factor 60,nucleus|cyclin-dependent protein kinase activating kinase holoenzyme complex|ribonucleoprotein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|apoptotic process|RNA splicing|",nucleotide binding|nucleic acid binding|DNA binding|RNA binding|identical protein binding|poly(A) RNA binding|,8,1.3,28.8,8,1.2,7.54,1.2,35.9,35.9,0.00265,0,0,0.7,2.2
ENSMUSG00000029135,FOSL2,fos-like antigen 2,nucleus|,"response to hypoxia|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to estradiol|positive regulation of transcription, DNA-templated|positive regulation of fibroblast proliferation|",RNA polymerase II regulatory region sequence-specific DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,1.1,27.5,10,0.8,8.34,1,35,35,0.00303,0,0,0.6,1.7
ENSMUSG00000071665,FOXR2,forkhead box R2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,8,0.4,0.486,8,-1.7,37.1,-1.7,34.7,-34.7,0.00316,0,0,-3,-1.1
ENSMUSG00000029038,SSU72,Ssu72 RNA polymerase II CTD phosphatase homolog (yeast),cellular_component|nucleus|cytoplasm|,mRNA polyadenylation|mRNA processing|dephosphorylation of RNA polymerase II C-terminal domain|,phosphoprotein phosphatase activity|CTD phosphatase activity|hydrolase activity|,8,1.6,11.7,8,1.4,22.6,1.4,33.7,33.7,0.00362,0,0,1,2.4
ENSMUSG00000031578,MAK16,MAK16 homolog (S. cerevisiae),cellular_component|nucleus|,biological_process|,poly(A) RNA binding|,9,-2.1,23,9,-1.4,12.4,-1.7,33.4,-33.4,0.00387,0,0,-3.3,-1.1
ENSMUSG00000036281,SNAPC4,"small nuclear RNA activating complex, polypeptide 4",nucleus|snRNA-activating protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|snRNA transcription from RNA polymerase II promoter|snRNA transcription from RNA polymerase III promoter|",DNA binding|chromatin binding|,7,2.7,33,10,0.7,5.32,2.6,33.1,33.1,0.00405,0,0,0.8,5
ENSMUSG00000027167,ELP4,elongation protein 4 homolog (S. cerevisiae),"nucleus|cytoplasm|transcription elongation factor complex|DNA-directed RNA polymerase II, holoenzyme|Elongator holoenzyme complex|","transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|histone acetylation|regulation of protein kinase activity|",histone acetyltransferase activity|phosphorylase kinase regulator activity|,10,1.8,34.5,10,0.4,1.07,1.7,32.8,32.8,0.00425,0,0,1.1,2.9
ENSMUSG00000045251,ZFP688,zinc finger protein 688,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-1.5,18,10,-1.6,14.7,-1.6,32.1,-32.1,0.00465,0,0,-3,-1.1
ENSMUSG00000061104,GM10094,predicted gene 10094,cellular_component|,biological_process|,molecular_function|,9,-0.2,0.181,9,-1.8,34.6,-1.8,31.7,-31.7,0.00495,0,0,-3,-1.3
ENSMUSG00000020248,NFYB,nuclear transcription factor-Y beta,intracellular|nucleus|nucleus|transcription factor complex|CCAAT-binding factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein complex binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|repressing transcription factor binding|,10,-0.7,7.04,10,-1.7,26.8,-0.8,31.5,-31.5,0.00508,0,0,-2.3,-0.5
ENSMUSG00000019977,HBS1L,Hbs1-like (S. cerevisiae),membrane|extracellular vesicular exosome|,translation|translational elongation|biological_process|,nucleotide binding|translation elongation factor activity|GTPase activity|GTP binding|,9,2.1,33.9,9,-0.1,0.218,2.1,30.6,30.6,0.00577,0,0,1.2,3.6
ENSMUSG00000028233,TGS1,trimethylguanosine synthase homolog (S. cerevisiae),extracellular space|nucleus|nucleus|cytoplasm|cytoplasm|,"RNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|7-methylguanosine RNA capping|methylation|7-methylguanosine cap hypermethylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|RNA trimethylguanosine synthase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,1,18.8,9,1.4,11.9,1,29.7,29.7,0.00669,0,0,0.6,1.8
ENSMUSG00000039183,NUBP2,nucleotide binding protein 2,nucleus|cytoplasm|cytoskeleton|spindle pole centrosome|,iron-sulfur cluster assembly|,"nucleotide binding|protein binding|ATP binding|metal ion binding|iron-sulfur cluster binding|4 iron, 4 sulfur cluster binding|",7,2,28.1,6,1,3.31,2,29.3,29.3,0.00715,0,0,1.3,3.3
ENSMUSG00000038510,RPF2,ribosome production factor 2 homolog (S. cerevisiae),nucleus|,biological_process|,poly(A) RNA binding|,8,1.3,25.8,8,0.8,4.78,1,29.2,29.2,0.00729,0,0,0.6,1.9
ENSMUSG00000032264,ZW10,zw10 kinetochore protein,"chromosome, centromeric region|kinetochore|spindle pole|nucleus|chromosome|cytoplasm|endoplasmic reticulum|kinetochore microtubule|cytoskeleton|membrane|membrane|",mitotic sister chromatid segregation|establishment of mitotic spindle orientation|protein complex assembly|transport|ER to Golgi vesicle-mediated transport|cell cycle|mitotic nuclear division|mitotic metaphase plate congression|mitotic cell cycle checkpoint|regulation of exit from mitosis|protein transport|vesicle-mediated transport|protein localization to kinetochore|cell division|,None,10,0.9,28.4,10,0.4,2.57,0.6,29.1,29.1,0.00743,0,0,0.4,1.8
ENSMUSG00000021697,DEPDC1B,DEP domain containing 1B,intracellular|,signal transduction|intracellular signal transduction|,molecular_function|GTPase activator activity|,10,-1.2,30.2,10,-0.2,0.338,-1.2,28.3,-28.3,0.00837,0,0,-2.5,-0.6
ENSMUSG00000028284,MAP3K7,mitogen-activated protein kinase kinase kinase 7,intracellular|cytoplasm|plasma membrane|membrane|,"MAPK cascade|activation of MAPK activity|angiogenesis|neural tube formation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|apoptotic process|response to stress|signal transduction|transforming growth factor beta receptor signaling pathway|I-kappaB phosphorylation|phosphorylation|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of JNK cascade|negative regulation of necroptotic process|negative regulation of ripoptosome assembly involved in necroptotic process|regulation of reactive oxygen species metabolic process|negative regulation of reactive oxygen species metabolic process|negative regulation of apoptotic signaling pathway|negative regulation of apoptotic signaling pathway|","nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|scaffold protein binding|",8,-1.3,31.3,8,0.6,2.3,-1.3,28.2,-28.2,0.00854,0,0,-2.7,-0.7
ENSMUSG00000057637,PRDM2,"PR domain containing 2, with ZNF domain",nucleus|,response to estradiol|,None,10,-1.4,31.2,10,0.3,2.83,-1.3,27.8,-27.8,0.00918,0,0,-2.9,-0.9
ENSMUSG00000093445,LRCH4,leucine-rich repeats and calponin homology (CH) domain containing 4,cytoplasm|PML body|PML body|,"negative regulation of transcription, DNA-templated|",protein binding|,10,-1,13.9,10,-0.7,14.9,-0.7,27.7,-27.7,0.00935,0,0,-1.3,-0.4
ENSMUSG00000019373,COPS3,"COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)",nucleus|cytoplasm|COP9 signalosome|COP9 signalosome|,in utero embryonic development|cullin deneddylation|,protein binding|,10,0.9,12,9,1,16,1,27.6,27.6,0.00956,0,0,0.7,1.6
ENSMUSG00000068966,ZBTB34,zinc finger and BTB domain containing 34,nucleus|,biological_process|,molecular_function|metal ion binding|,10,1.3,21.5,10,0.6,7.24,0.8,27.5,27.5,0.0097,0,0,0.4,1.6
ENSMUSG00000016253,NELFCD,"negative elongation factor complex member C/D, Th1l",nucleus|membrane|NELF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",None,8,-1.2,28.1,8,-0.6,1.28,-1.1,27.4,-27.4,0.00997,0,0,-2.5,-0.5
ENSMUSG00000066007,ZFP600,zinc finger protein 600,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,8,-1.4,26.4,8,-0.4,1.27,-1.3,25.5,-25.5,0.0138,0,0,-2.7,-0.6
ENSMUSG00000069305,HIST1H4N,"histone cluster 1, H4n",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,6,1.3,27.9,6,-0.4,0.698,1.3,25.4,25.4,0.014,0,0,0.7,2
ENSMUSG00000040356,SKIV2L,superkiller viralicidic activity 2-like (S. cerevisiae),nucleus|Ski complex|,None,nucleotide binding|helicase activity|ATP binding|hydrolase activity|,10,2.7,22.5,10,0.7,6.59,0.7,25.4,25.4,0.014,0,0,0.2,4.2
ENSMUSG00000055436,SRSF11,serine/arginine-rich splicing factor 11,nucleus|,biological_process|,poly(A) RNA binding|,9,1.2,14.3,10,1.5,11.2,1.3,24.8,24.8,0.0155,0,0,0.5,2.4
ENSMUSG00000078970,WDR92,WD repeat domain 92,cellular_component|,apoptotic process|histone lysine methylation|,methylated histone binding|,9,-1.3,24.5,8,-0.6,2.67,-1.2,24.5,-24.5,0.0165,0,0,-2.6,-0.5
ENSMUSG00000028798,EIF3I,"eukaryotic translation initiation factor 3, subunit I","cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|extracellular vesicular exosome|eukaryotic translation initiation factor 3 complex, eIF3m|",translation|translational initiation|translational initiation|,translation initiation factor activity|translation initiation factor activity|protein binding|,7,1.2,27,7,-0.7,0.403,1.2,24.4,24.4,0.0167,0,0,0.7,2
ENSMUSG00000034820,CPSF7,cleavage and polyadenylation specific factor 7,nucleus|mRNA cleavage factor complex|membrane|,mRNA processing|protein tetramerization|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-1.6,22.9,10,-0.4,6.36,-0.7,24.3,-24.3,0.017,0,0,-2.4,-0.4
ENSMUSG00000020962,GTF2A1,"general transcription factor II A, 1",nucleus|nucleus|transcription factor TFIIA complex|transcription factor TFIIA complex|cytoplasm|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|",RNA polymerase II repressing transcription factor binding|DNA binding|protein binding|transcription factor binding|TBP-class protein binding|protein heterodimerization activity|,9,2.3,15.9,9,1.5,10.1,2.3,24.2,24.2,0.0173,0,0,1.4,3.8
ENSMUSG00000026019,WDR12,WD repeat domain 12,"nucleus|nucleoplasm|nucleolus|preribosome, large subunit precursor|PeBoW complex|","maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|rRNA processing|Notch signaling pathway|cell proliferation|ribosome biogenesis|",protein binding|,9,-1,20.3,6,-0.7,4.67,-0.9,24.1,-24.1,0.0177,0,0,-1.6,-0.5
ENSMUSG00000014039,PRDM15,PR domain containing 15,nucleus|,biological_process|,molecular_function|,10,-0.1,0.0625,10,-2.5,27.2,-2.5,23.8,-23.8,0.0189,0,0,-4.7,-1.5
ENSMUSG00000026761,ORC4,"origin recognition complex, subunit 4",origin recognition complex|nucleus|nuclear origin of replication recognition complex|,DNA replication|DNA replication initiation|,nucleotide binding|DNA binding|DNA replication origin binding|ATP binding|,8,-1.4,26,7,0.2,0.179,-1.4,23.1,-23.1,0.0215,0,0,-2.9,-0.8
ENSMUSG00000002325,IRF9,interferon regulatory factor 9,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|type I interferon biosynthetic process|",regulatory region DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0.7,11.1,10,0.6,12.2,0.7,22.9,22.9,0.0224,0,0,0.4,1.2
ENSMUSG00000067919,REX2,reduced expression 2,nucleus|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,7,-1.7,25.2,7,-0.2,0.474,-1.4,22.7,-22.7,0.0233,0,0,-3,-0.8
ENSMUSG00000021541,TRPC7,"transient receptor potential cation channel, subfamily C, member 7",nucleus|cis-Golgi network|plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,transport|ion transport|calcium ion transport|manganese ion transport|transmembrane transport|calcium ion transmembrane transport|,ion channel activity|calcium channel activity|,10,1.4,20.8,10,1.3,2.31,1.4,22.7,22.7,0.0233,0,0,0.7,2.8
ENSMUSG00000020454,EIF4ENIF1,eukaryotic translation initiation factor 4E nuclear import factor 1,nucleus|cytoplasm|cytosol|membrane|intracellular membrane-bounded organelle|,transport|biological_process|protein transport|,protein binding|poly(A) RNA binding|,10,-1.3,25.1,10,1,0.481,-1.2,22.5,-22.5,0.0242,0,0,-2.8,-0.5
ENSMUSG00000037296,LSM1,"LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)",nucleus|cytoplasm|ribonucleoprotein complex|,mRNA processing|RNA splicing|histone mRNA catabolic process|,RNA binding|poly(A) RNA binding|,9,-0.4,2.42,9,-1.5,23.2,-1.2,22.4,-22.4,0.0249,0,0,-2.4,-0.4
ENSMUSG00000049658,BDP1,"B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB",nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|chromatin binding|,9,3.4,25.3,9,-0.2,1.59,3.4,22.2,22.2,0.026,0,0,2.5,6
ENSMUSG00000021051,PPP2R5E,"protein phosphatase 2, regulatory subunit B', epsilon",protein phosphatase type 2A complex|cytoplasm|cytoplasm|,signal transduction|,protein phosphatase type 2A regulator activity|,10,-1.6,23,10,-0.4,0.922,-1.2,21.8,-21.8,0.0286,0,0,-2.8,-0.6
ENSMUSG00000032998,FOXJ3,forkhead box J3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,1.2,15.8,10,0.8,6.38,0.8,21.6,21.6,0.0299,0,0,0.4,1.6
ENSMUSG00000079083,JRKL,Jrk-like,cellular_component|nucleus|,biological_process|,molecular_function|nucleic acid binding|DNA binding|,10,-1.2,21.6,10,-0.1,0.46,-1.1,21.1,-21.1,0.0339,0,0,-2.5,-0.5
ENSMUSG00000078619,SMARCD2,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2",nuclear chromatin|nucleus|SWI/SNF complex|protein complex|,"nucleosome disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|ATP-dependent chromatin remodeling|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|nucleosomal DNA binding|,10,-1.7,23,9,1.6,6.02,-1.4,20.8,-20.8,0.0363,0,0,-3,-0.8
ENSMUSG00000041777,CIR1,"corepressor interacting with RBPJ, 1",histone deacetylase complex|nucleus|cytoplasm|cytoskeleton|nuclear speck|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",protein binding|histone deacetylase binding|,9,1.3,19.5,10,0.7,2.15,1,20.8,20.8,0.0363,0,0,0.4,1.8
ENSMUSG00000061559,WDR61,WD repeat domain 61,nucleus|cytoplasm|Cdc73/Paf1 complex|transcriptionally active chromatin|Ski complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Wnt signaling pathway|positive regulation of transcription elongation from RNA polymerase II promoter|negative regulation of myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of histone H3-K4 methylation|histone H3-K4 trimethylation|positive regulation of histone H3-K79 methylation|",molecular_function|,9,-0.9,12.2,10,-1.1,8.99,-1,20.5,-20.5,0.039,0,0,-1.6,-0.6
ENSMUSG00000029614,RPL6,ribosomal protein L6,intracellular|nucleus|nucleus|nucleolus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|,translation|,structural constituent of ribosome|poly(A) RNA binding|,3,1.9,4.44,4,2.2,16.6,2.1,20.4,20.4,0.04,0,0,1.6,3.9
ENSMUSG00000021890,EAF1,ELL associated factor 1,nucleus|cytoplasm|ELL-EAF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",transcription factor binding|,10,0.8,9.52,9,0.9,11,0.8,20,20,0.0445,0,0,0.5,1.4
ENSMUSG00000043969,EMX2,empty spiracles homeobox 2,nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|brain development|anterior/posterior pattern specification|anterior/posterior pattern specification|regulation of gene expression|dentate gyrus development|cerebral cortex regionalization|cerebral cortex regionalization|cell proliferation in forebrain|forebrain cell migration|cerebral cortex development|neuron differentiation|forebrain development|forebrain development|response to drug|renal system development|",DNA binding|sequence-specific DNA binding|,10,-0.3,1.9,10,2.4,23.3,2.4,19.8,19.8,0.047,0,0,0.6,4
ENSMUSG00000031931,ANKRD49,ankyrin repeat domain 49,cellular_component|,"positive regulation of transcription, DNA-templated|",molecular_function|,9,1.5,17,9,0.6,5.76,0.8,19.8,19.8,0.047,0,0,0.5,2.1
ENSMUSG00000040720,1110037F02RIK,RIKEN cDNA 1110037F02 gene,cellular_component|nucleus|,mRNA processing|biological_process|RNA splicing|,poly(A) RNA binding|,10,-0.9,17.8,9,-1.2,2.84,-1.1,19.8,-19.8,0.047,0,0,-1.7,-0.5
ENSMUSG00000027547,SALL4,sal-like 4 (Drosophila),heterochromatin|nucleus|transcription factor complex|cytoplasm|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|inner cell mass cell proliferation|neural tube closure|neural tube closure|ventricular septum development|ventricular septum development|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|tissue development|stem cell maintenance|neural tube development|embryonic limb morphogenesis|embryonic limb morphogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,1.5,19.4,10,1,1.24,1.3,19.6,19.6,0.0497,0,0,0.6,2.8
ENSMUSG00000031487,BRF2,"BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like",cellular_component|nucleus|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|",zinc ion binding|metal ion binding|,10,1.6,11.5,9,1.1,8.91,1.2,19.5,19.5,0.0511,0,0,0.7,2.3
ENSMUSG00000022685,PARN,poly(A)-specific ribonuclease (deadenylation nuclease),nucleus|cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|nuclear-transcribed mRNA poly(A) tail shortening|mRNA catabolic process|",nucleotide binding|nucleic acid binding|RNA binding|nuclease activity|exonuclease activity|poly(A)-specific ribonuclease activity|protein binding|hydrolase activity|protein kinase binding|poly(A) RNA binding|metal ion binding|,10,0.3,0.482,10,3.2,21.9,3.2,19.4,19.4,0.0524,0,0,2.6,6
ENSMUSG00000001785,PWP1,PWP1 homolog (S. cerevisiae),nucleus|nucleolus|Golgi apparatus|,biological_process|,molecular_function|,10,2.2,19.9,10,0.8,2.12,2.2,19.4,19.4,0.0524,0,0,1.4,3.7
ENSMUSG00000073062,ZXDB,"zinc finger, X-linked, duplicated B",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|metal ion binding|,10,1.6,11,10,1,9.66,1.2,19.4,19.4,0.0524,0,0,0.7,2.2
ENSMUSG00000027080,MED19,mediator complex subunit 19,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|biological_process|",RNA polymerase II transcription cofactor activity|protein binding|,8,1.3,22.1,9,-1.1,7.26,1.3,19.3,19.3,0.0535,0,0,0.4,1.9
ENSMUSG00000024837,DMRT1,doublesex and mab-3 related transcription factor 1,intracellular|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|male germ cell proliferation|developmental process involved in reproduction|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|sex differentiation|germ cell migration|male gonad development|cell differentiation|male sex determination|intracellular signal transduction|negative regulation of meiosis|positive regulation of mitosis|positive regulation of transcription from RNA polymerase II promoter|male sex differentiation|oocyte development|Sertoli cell differentiation|Sertoli cell development|positive regulation of meiosis I|regulation of nodal signaling pathway|positive regulation of male gonad development|",core promoter proximal region sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,-1.9,22.8,10,0.5,2.85,-1.9,19.3,-19.3,0.0535,0,0,-3.9,-1.2
ENSMUSG00000066415,MSL2,male-specific lethal 2 homolog (Drosophila),MSL complex|,histone H4-K16 acetylation|,"molecular_function|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.8,15.8,10,-1.1,4.22,-0.8,19.2,-19.2,0.0547,0,0,-1.5,-0.5
ENSMUSG00000022635,ZCRB1,zinc finger CCHC-type and RNA binding motif 1,nucleus|spliceosomal complex|U12-type spliceosomal complex|,mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-2.2,22.6,10,0.7,2.45,-2.2,19.1,-19.1,0.0559,0,0,-4,-1.4
ENSMUSG00000059273,ZC3H4,zinc finger CCCH-type containing 4,None,None,poly(A) RNA binding|metal ion binding|,10,1.2,14,10,-1.5,7.46,1,19,19,0.057,0,0,0.4,1.8
ENSMUSG00000023026,DIP2B,DIP2 disco-interacting protein 2 homolog B (Drosophila),nucleus|cytoplasm|membrane|extracellular vesicular exosome|,biological_process|metabolic process|,molecular_function|catalytic activity|transcription factor binding|,10,1,3.39,10,0.9,16,0.9,18.9,18.9,0.0579,0,0,0.4,1.5
ENSMUSG00000044770,SCML4,sex comb on midleg-like 4 (Drosophila),cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|,10,1.4,21.1,10,-0.2,0.492,1.3,18.1,18.1,0.0661,0,0,0.4,2.8
ENSMUSG00000049327,SETD8,SET domain containing (lysine methyltransferase) 8,nucleus|chromosome|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|mitotic nuclear division|chromatin modification|peptidyl-lysine monomethylation|methylation|histone lysine methylation|regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of transcription, DNA-templated|cell division|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|p53 binding|transcription corepressor activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",8,-1.4,12.6,9,-1.3,5.97,-1.4,18.1,-18.1,0.0661,0,0,-2,-0.8
ENSMUSG00000048897,ZFP710,zinc finger protein 710,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.4,2.66,10,0.9,16,0.9,18,18,0.0672,0,0,0.4,1.4
ENSMUSG00000039756,DNTTIP2,"deoxynucleotidyltransferase, terminal, interacting protein 2",nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",poly(A) RNA binding|,9,0.1,0.22,9,-1.6,20.7,-1.6,17.4,-17.4,0.0729,0,0,-3,-0.8
ENSMUSG00000063334,KRR1,"KRR1, small subunit (SSU) processome component, homolog (yeast)",nucleus|nucleolus|membrane|ribonucleoprotein complex|intercellular bridge|,rRNA processing|biological_process|ribosome biogenesis|,RNA binding|poly(A) RNA binding|,9,-0.9,18.6,9,0.4,1.58,-0.9,17.3,-17.3,0.0737,0,0,-2,2.4
ENSMUSG00000061887,SSBP3,single-stranded DNA binding protein 3,nucleus|protein complex|,"hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein complex assembly|positive regulation of cell proliferation|prechordal plate formation|midbrain-hindbrain boundary initiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|head development|head morphogenesis|positive regulation of anterior head development|",DNA binding|single-stranded DNA binding|protein binding|,10,-0.8,9.54,10,-0.5,8.8,-0.6,17,-17,0.0756,0,0,-1.2,-0.3
ENSMUSG00000074899,SPTBN5,"spectrin beta, non-erythrocytic 5",cytoplasm|microtubule associated complex|axoneme|cortical cytoskeleton|photoreceptor connecting cilium|protein complex|apical cortex|extracellular vesicular exosome|photoreceptor disc membrane|,Golgi organization|lysosomal transport|protein homooligomerization|,opsin binding|actin binding|protein binding|protein C-terminus binding|kinesin binding|spectrin binding|spectrin binding|myosin tail binding|dynactin binding|protein self-association|dynein intermediate chain binding|protein heterodimerization activity|actin filament binding|,10,1.4,20.2,10,-0.2,0.59,1.4,16.9,16.9,0.0763,0,0,0.6,2.9
ENSMUSG00000027185,NAT10,N-acetyltransferase 10,nucleus|membrane|,biological_process|,"nucleotide binding|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|ATP binding|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|poly(A) RNA binding|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",8,-0.9,8.02,8,-0.7,9.46,-0.8,16.9,-16.9,0.0763,0,0,-1.5,-0.4
ENSMUSG00000029913,PRDM5,PR domain containing 5,nucleus|,"mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone deacetylation|methylation|negative regulation of transcription, DNA-templated|histone H3-K9 methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|transcription regulatory region sequence-specific DNA binding|nucleic acid binding|DNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|sequence-specific DNA binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|transcription regulatory region DNA binding|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|repressing transcription factor binding|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,1.5,20,10,-0.5,1.11,1.4,16.8,16.8,0.0769,0,0,0.6,2.9
ENSMUSG00000075327,ZBTB2,zinc finger and BTB domain containing 2,cellular_component|nucleus|,biological_process|,molecular_function|metal ion binding|,10,-0.6,3.97,10,-0.6,13.1,-0.6,16.7,-16.7,0.0774,0,0,-1,-0.3
ENSMUSG00000024491,RBM27,RNA binding motif protein 27,nucleus|cytoplasm|,mRNA processing|biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|metal ion binding|,8,0.4,1.26,8,1.3,16.3,1.2,16.3,16.3,0.0798,0,0,0.7,1.9
ENSMUSG00000037475,THOC2,THO complex 2,transcription export complex|THO complex|THO complex part of transcription export complex|nucleus|,cell morphogenesis|blastocyst development|mRNA processing|mRNA export from nucleus|transport|RNA splicing|regulation of gene expression|regulation of mRNA export from nucleus|poly(A)+ mRNA export from nucleus|stem cell division|viral mRNA export from host cell nucleus|mRNA transport|,RNA binding|mRNA binding|protein binding|,9,1.2,14.7,9,0.8,2.47,0.8,16.2,16.2,0.0805,0,0,0.4,2
ENSMUSG00000041229,PHF8,PHD finger protein 8,nucleus|nucleolus|microtubule cytoskeleton|,"G1/S transition of mitotic cell cycle|histone H3-K9 demethylation|histone H4-K20 demethylation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase I promoter|oxidation-reduction process|negative regulation of chromatin silencing at rDNA|histone H3-K36 demethylation|histone H3-K27 demethylation|","chromatin binding|iron ion binding|zinc ion binding|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|histone demethylase activity|histone demethylase activity (H3-K9 specific)|methylated histone binding|histone demethylase activity (H4-K20 specific)|histone demethylase activity (H3-K36 specific)|histone demethylase activity (H3-K27 specific)|",10,-1.1,16.4,10,-0.3,1.7,-0.7,16,-16,0.0816,0,0,-2.4,-0.3
ENSMUSG00000004268,EMG1,EMG1 nucleolar protein homolog (S. cerevisiae),cellular_component|nucleus|,blastocyst development|rRNA processing|nucleologenesis|rRNA methylation|methylation|ribosome biogenesis|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|rRNA binding|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (pseudouridine) methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",8,-1.2,17.5,8,-0.3,0.856,-0.9,15.8,-15.8,0.0828,0,0,-1.9,-0.5
ENSMUSG00000009640,DMAP1,DNA methyltransferase 1-associated protein 1,nucleus|replication fork|cytoplasm|NuA4 histone acetyltransferase complex|,"negative regulation of transcription from RNA polymerase II promoter|DNA repair|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|regulation of growth|positive regulation of transcription factor import into nucleus|histone H4 acetylation|histone H2A acetylation|negative regulation of transcription, DNA-templated|",RNA polymerase II repressing transcription factor binding|chromatin binding|transcription corepressor activity|protein binding|,10,1.5,16,9,0.5,2.86,0.8,15.7,15.7,0.0835,0,0,-1.6,3
ENSMUSG00000053950,ADNP2,ADNP homeobox 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|neuron differentiation|positive regulation of cell growth|cellular response to oxidative stress|negative regulation of cell death|cellular response to retinoic acid|",DNA binding|metal ion binding|,10,0.5,3.68,10,1,13.4,0.7,15.6,15.6,0.0841,0,0,0.4,1.4
ENSMUSG00000060639,HIST1H4I,"histone cluster 1, H4i",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,9,0,0,8,-1.7,18.5,-1.7,15.5,-15.5,0.0847,0,0,-3,-0.6
ENSMUSG00000049396,GEMIN4,gem (nuclear organelle) associated protein 4,nucleolus|cytosol|Cajal body|membrane|SMN complex|SMN-Sm protein complex|extracellular vesicular exosome|,spliceosomal snRNP assembly|,ribonucleoprotein complex binding|,10,-0.6,5.31,9,-1.5,12.1,-0.6,15.4,-15.4,0.0854,0,0,-2.2,-0.3
ENSMUSG00000030880,POLR3E,polymerase (RNA) III (DNA directed) polypeptide E,nucleus|DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III complex|centrosome|,"immune system process|transcription, DNA-templated|innate immune response|defense response to virus|",RNA polymerase III activity|DNA-directed RNA polymerase activity|,9,0.8,5.18,9,1.1,10.8,1,15.3,15.3,0.086,0,0,0.4,1.9
ENSMUSG00000033047,EIF3L,"eukaryotic translation initiation factor 3, subunit L",fibrillar center|nucleoplasm|nucleolus|cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|membrane|,translation|translational initiation|translational initiation|,translation initiation factor activity|translation initiation factor activity|protein binding|poly(A) RNA binding|,8,-0.6,4.33,8,-0.7,11,-0.7,14.9,-14.9,0.0886,0,0,-1.3,-0.4
ENSMUSG00000050945,ZFP438,zinc finger protein 438,nucleus|,"negative regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|,10,-1.4,14.9,10,0.3,0.599,-1.1,14.7,-14.7,0.09,0,0,-2.8,-0.6
ENSMUSG00000033902,MAPKBP1,mitogen-activated protein kinase binding protein 1,cellular_component|,activation of JNKK activity|,protein binding|,10,1.5,17.7,10,-0.8,4.27,1.5,14.4,14.4,0.0922,0,0,0.7,3
ENSMUSG00000004393,DDX56,DEAD (Asp-Glu-Ala-Asp) box polypeptide 56,nucleus|nucleolus|nucleolus|membrane|,rRNA processing|biological_process|ribosome biogenesis|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,8,1.3,17.2,7,-0.8,10.3,1.2,14.3,14.3,0.0928,0,0,-0.6,2
ENSMUSG00000094622,GM3055,predicted gene 3055,cellular_component|,biological_process|,molecular_function|,10,1.3,16.7,10,-0.2,0.268,0.5,14.2,14.2,0.0935,0,0,0.3,1.9
ENSMUSG00000070803,CITED4,"Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4",nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|response to estrogen|positive regulation of transcription, DNA-templated|regulation of RNA biosynthetic process|",transcription coactivator activity|transcription coactivator activity|,9,2.3,14.5,9,0.7,2.29,2.3,13.9,13.9,0.096,0,0,0.4,4
ENSMUSG00000067150,XPO5,exportin 5,intracellular|cell|nucleus|cytoplasm|,protein export from nucleus|transport|intracellular protein transport|protein transport|gene silencing by RNA|,tRNA binding|RNA binding|Ran GTPase binding|protein transporter activity|poly(A) RNA binding|,9,-0.6,5.09,9,-1.5,11.7,-1,13.9,-13.9,0.096,0,0,-2.4,-0.4
ENSMUSG00000030180,KDM5A,lysine (K)-specific demethylase 5A,intracellular|nucleus|cytoplasm|cyclin-dependent protein kinase activating kinase holoenzyme complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|chromatin modification|positive regulation of transcription, DNA-templated|oxidation-reduction process|","sulfonate dioxygenase activity|DNA binding|chromatin binding|protein binding|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,1.9,17.3,10,-0.1,0.432,1.9,13.9,13.9,0.096,0,0,0.9,3.9
ENSMUSG00000054309,CPSF3,cleavage and polyadenylation specificity factor 3,nucleus|mRNA cleavage and polyadenylation specificity factor complex|mRNA cleavage and polyadenylation specificity factor complex|ribonucleoprotein complex|,"mRNA polyadenylation|mRNA processing|histone mRNA 3'-end processing|histone mRNA 3'-end processing|RNA phosphodiester bond hydrolysis, endonucleolytic|",RNA binding|mRNA binding|nuclease activity|endonuclease activity|endoribonuclease activity|5'-3' exonuclease activity|hydrolase activity|metal ion binding|,8,1.5,15.5,8,0.5,1.45,1.4,13.8,13.8,0.0966,0,0,0.5,2.7
ENSMUSG00000001415,SMG5,"Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)",nucleus|cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of dephosphorylation|",protein phosphatase 2A binding|,10,0.5,2.37,10,0.7,12.1,0.6,13.5,13.5,0.0989,0,0,0.3,1.3
ENSMUSG00000046957,SPZ1,spermatogenic leucine zipper 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.6,2.35,10,-0.6,11.4,-0.6,13.5,-13.5,0.0989,0,0,-1.1,-0.3
ENSMUSG00000070003,SSBP4,single stranded DNA binding protein 4,cellular_component|,biological_process|,molecular_function|,10,-0.6,6.14,10,-0.6,7.72,-0.6,13.5,-13.5,0.0989,0,0,-1.2,-0.3
ENSMUSG00000019837,GTF3C6,"general transcription factor IIIC, polypeptide 6, alpha",transcription factor TFIIIC complex|nucleus|,"transcription, DNA-templated|transcription from RNA polymerase III promoter|",DNA binding|,9,1.3,13.6,9,0.6,0.65,1.1,13.3,13.3,0.101,0,0,0.4,2
ENSMUSG00000056749,NFIL3,"nuclear factor, interleukin 3, regulated",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|circadian rhythm|positive regulation of gene expression|positive regulation of gene expression|rhythmic process|cellular response to interleukin-4|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,1.1,8.21,10,0.7,5.61,0.7,13.3,13.3,0.101,0,0,0.3,1.6
ENSMUSG00000022119,RBM26,RNA binding motif protein 26,cellular_component|,mRNA processing|negative regulation of phosphatase activity|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|metal ion binding|,10,0.4,1.19,10,1,13.2,0.7,13.2,13.2,0.102,0,0,0.3,1.6
ENSMUSG00000022312,EIF3H,"eukaryotic translation initiation factor 3, subunit H","cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|membrane|intracellular membrane-bounded organelle|protein complex|extracellular vesicular exosome|eukaryotic translation initiation factor 3 complex, eIF3m|",translation|translational initiation|translational initiation|,translation initiation factor activity|translation initiation factor activity|protein complex binding|poly(A) RNA binding|,10,-0.7,6.51,10,-1.2,7.89,-1.1,13,-13,0.103,0,0,-1.8,-0.4
ENSMUSG00000022009,NUFIP1,nuclear fragile X mental retardation protein interacting protein 1,nucleus|nucleus|perichromatin fibrils|perichromatin fibrils|nucleolus|nucleolus|transcription elongation factor complex|transcription elongation factor complex|nuclear matrix|nuclear matrix|cytosolic ribosome|cytosolic ribosome|presynaptic active zone|presynaptic active zone|pre-snoRNP complex|,box C/D snoRNP assembly|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|,"RNA binding|RNA binding|protein binding|snoRNA binding|protein binding, bridging|identical protein binding|metal ion binding|",9,1.5,15.7,9,-0.4,1.75,1.5,13,13,0.103,0,0,0.6,2.9
ENSMUSG00000033352,MAP2K4,mitogen-activated protein kinase kinase 4,intracellular|nucleus|cytoplasm|cytosol|axon|dendrite cytoplasm|perikaryon|,MAPK cascade|positive regulation of protein phosphorylation|protein phosphorylation|apoptotic process|response to stress|JNK cascade|activation of JUN kinase activity|phosphorylation|positive regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of DNA replication|positive regulation of nitric-oxide synthase biosynthetic process|cell growth involved in cardiac muscle cell development|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase kinase binding|",10,-1.4,14.7,10,1,1.73,-1.1,12.9,-12.9,0.104,0,0,-2.8,-0.5
ENSMUSG00000066900,SUDS3,suppressor of defective silencing 3 homolog (S. cerevisiae),nucleus|cytoplasm|plasma membrane|Sin3 complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|chromatin modification|histone deacetylation|positive regulation of apoptotic process|negative regulation of transcription, DNA-templated|",histone deacetylase activity|protein binding|enzyme binding|identical protein binding|protein homodimerization activity|histone deacetylase binding|,9,1.3,14.9,9,0.2,0.138,1.2,12.7,12.7,0.106,0,0,-0.9,2
ENSMUSG00000025626,PHF6,PHD finger protein 6,nucleus|nucleoplasm|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|zinc ion binding|tubulin binding|enzyme binding|histone binding|histone deacetylase binding|ribonucleoprotein complex binding|poly(A) RNA binding|metal ion binding|phosphoprotein binding|scaffold protein binding|,10,-0.4,1.13,10,-0.7,12.6,-0.6,12.7,-12.7,0.106,0,0,-1.1,-0.3
ENSMUSG00000078348,SF3B5,"splicing factor 3b, subunit 5",nucleus|spliceosomal complex|U12-type spliceosomal complex|,mRNA processing|RNA splicing|,molecular_function|,6,-1,9.12,5,-1.2,3.45,-1.2,12.1,-12.1,0.112,0,0,-2,-0.6
ENSMUSG00000031935,MED17,mediator complex subunit 17,nucleus|transcription factor complex|membrane|mediator complex|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|stem cell maintenance|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|transcription cofactor activity|transcription coactivator activity|receptor activity|thyroid hormone receptor binding|,9,1.6,8.9,10,0.8,4.64,1.1,12.1,12.1,0.112,0,0,0.7,2.6
ENSMUSG00000045624,ESF1,"ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)",extracellular space|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",poly(A) RNA binding|,9,-1.1,11.5,10,0.3,1.09,-1.1,12.1,-12.1,0.112,0,0,-2,-0.6
ENSMUSG00000061650,MED9,mediator complex subunit 9,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|biological_process|",RNA polymerase II transcription cofactor activity|protein binding|,10,-0.8,10.6,10,-0.4,2.53,-0.7,12.1,-12.1,0.112,0,0,-1.5,-0.3
ENSMUSG00000027763,MBNL1,muscleblind-like 1 (Drosophila),nucleus|nucleus|cytoplasm|cytoplasm|cytoplasmic stress granule|,"alternative mRNA splicing, via spliceosome|alternative mRNA splicing, via spliceosome|regulation of alternative mRNA splicing, via spliceosome|mRNA splice site selection|mRNA processing|skeletal muscle tissue development|RNA splicing|regulation of RNA splicing|myoblast differentiation|",RNA binding|double-stranded RNA binding|poly(A) RNA binding|metal ion binding|,10,-0.3,1.51,10,-0.6,11.8,-0.5,12,-12,0.113,0,0,-1,-0.2
ENSMUSG00000013833,MED16,mediator complex subunit 16,nucleus|membrane|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of receptor activity|",transcription cofactor activity|catalytic activity|receptor activity|thyroid hormone receptor coactivator activity|thyroid hormone receptor binding|,10,0.2,0.999,10,0.7,13.3,0.7,11.9,11.9,0.114,0,0,0.3,1.4
ENSMUSG00000001016,ILF2,interleukin enhancer binding factor 2,nucleus|nucleus|nucleolus|cytoplasm|membrane|ribonucleoprotein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|immune response|positive regulation of transcription, DNA-templated|",DNA binding|DNA binding|RNA binding|double-stranded RNA binding|ATP binding|transferase activity|poly(A) RNA binding|,9,-0.7,4.61,8,-0.7,7.62,-0.7,11.9,-11.9,0.114,0,0,-1.5,-0.3
ENSMUSG00000017264,EXOSC10,exosome component 10,nuclear exosome (RNase complex)|exosome (RNase complex)|intracellular|nucleus|nucleolus|nucleolus|cytoplasm|membrane|transcriptionally active chromatin|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|maturation of 5.8S rRNA|nuclear-transcribed mRNA catabolic process|nucleobase-containing compound metabolic process|rRNA processing|RNA processing|dosage compensation by inactivation of X chromosome|cellular metabolic process|nuclear mRNA surveillance|CUT catabolic process|nuclear polyadenylation-dependent rRNA catabolic process|histone mRNA catabolic process|nuclear retention of unspliced pre-mRNA at the site of transcription|RNA phosphodiester bond hydrolysis, exonucleolytic|",nucleotide binding|3'-5'-exoribonuclease activity|nucleic acid binding|RNA binding|catalytic activity|nuclease activity|exonuclease activity|exoribonuclease activity|5'-3' exoribonuclease activity|3'-5' exonuclease activity|hydrolase activity|poly(A) RNA binding|,8,-0.6,4.19,9,-0.8,8.18,-0.8,11.8,-11.8,0.115,0,0,-1.4,-0.3
ENSMUSG00000026404,DDX59,DEAD (Asp-Glu-Ala-Asp) box polypeptide 59,intracellular|nucleus|cytoplasm|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|hydrolase activity|metal ion binding|,10,-0.4,1.13,10,-1,11.9,-0.9,11.7,-11.7,0.116,0,0,-1.6,-0.4
ENSMUSG00000035623,RSF1,remodeling and spacing factor 1,nucleus|RSF complex|,"nucleosome assembly|chromatin remodeling|DNA-templated transcription, initiation|nucleosome positioning|negative regulation of DNA binding|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of viral transcription|",histone binding|metal ion binding|,10,-0.4,2.65,10,-0.8,10.3,-0.7,11.7,-11.7,0.116,0,0,-1.4,-0.3
ENSMUSG00000030751,PSMA1,"proteasome (prosome, macropain) subunit, alpha type 1","proteasome complex|nucleus|cytoplasm|centrosome|proteasome core complex|proteasome core complex, alpha-subunit complex|extracellular vesicular exosome|",immune system process|negative regulation of inflammatory response to antigenic stimulus|negative regulation of inflammatory response to antigenic stimulus|proteolysis|ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,lipopolysaccharide binding|endopeptidase activity|threonine-type endopeptidase activity|protein binding|peptidase activity|hydrolase activity|,8,-0.7,6.09,7,-0.6,5.96,-0.7,11.6,-11.6,0.117,0,0,-1.3,-0.3
ENSMUSG00000031865,DCTN1,dynactin 1,kinetochore|spindle pole|cell|cytoplasm|centrosome|cytoskeleton|cytoplasmic dynein complex|dynactin complex|microtubule|membrane|dynein complex|cell leading edge|protein complex|,transport|microtubule-based transport|melanosome transport|,motor activity|protein binding|dynein binding|,10,0.6,4.43,10,0.7,7.5,0.7,11.5,11.5,0.118,0,0,0.3,1.4
ENSMUSG00000020700,MAP3K3,mitogen-activated protein kinase kinase kinase 3,intracellular|,protein phosphorylation|phosphorylation|intracellular signal transduction|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.1,0.184,10,0.7,13.1,0.7,11.5,11.5,0.118,0,0,0.3,1.5
ENSMUSG00000038725,PKHD1L1,polycystic kidney and hepatic disease 1-like 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1,12.6,10,-0.3,0.333,0.9,11.4,11.4,0.12,0,0,0.3,1.7
ENSMUSG00000064127,MED14,mediator complex subunit 14,nucleus|membrane|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|stem cell maintenance|intracellular steroid hormone receptor signaling pathway|androgen receptor signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|transcription cofactor activity|transcription coactivator activity|receptor activity|thyroid hormone receptor binding|,6,-1,10.8,4,-0.6,1.62,-0.9,11.3,-11.3,0.121,0,0,-1.9,-0.4
ENSMUSG00000070319,EIF3G,"eukaryotic translation initiation factor 3, subunit G",nucleus|cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|,translation|translational initiation|translational initiation|,nucleotide binding|nucleic acid binding|RNA binding|translation initiation factor activity|translation initiation factor activity|protein binding|poly(A) RNA binding|,5,0.5,0.814,5,1.5,12.4,1.5,11.3,11.3,0.121,0,0,0.6,3
ENSMUSG00000026751,NR5A1,"nuclear receptor subfamily 5, group A, member 1",nucleus|nucleus|,"luteinization|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|male gonad development|male gonad development|tissue development|multicellular organismal aging|reproductive process|cell differentiation|adrenal gland development|adrenal gland development|hormone metabolic process|steroid hormone mediated signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|maintenance of protein location in nucleus|positive regulation of male gonad development|positive regulation of male gonad development|negative regulation of female gonad development|",DNA binding|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|protein binding|phospholipid binding|zinc ion binding|lipid binding|enzyme binding|sequence-specific DNA binding|metal ion binding|,10,1.3,12.5,10,0.4,0.749,0.8,11.2,11.2,0.122,0,0,0.3,1.9
ENSMUSG00000029389,DDX55,DEAD (Asp-Glu-Ala-Asp) box polypeptide 55,membrane|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|poly(A) RNA binding|,7,2.3,14,7,0.1,0.24,2.3,11.1,11.1,0.123,0,0,0.4,4
ENSMUSG00000047907,TSHZ2,teashirt zinc finger family member 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|regulation of gene expression|",DNA binding|protein binding|metal ion binding|,10,-0.8,11.7,10,-0.1,0.0798,-0.8,11,-11,0.124,0,0,-1.6,-0.3
ENSMUSG00000029627,ZKSCAN14,zinc finger with KRAB and SCAN domains 14,intracellular|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,9,2.1,4.85,10,-1,10.7,-0.9,11,-11,0.124,0,0,-1.8,-0.3
ENSMUSG00000001225,SLC26A3,"solute carrier family 26, member 3",intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|apical plasma membrane|brush border membrane|sperm midpiece|,transport|anion transport|sulfate transport|bicarbonate transport|ion transmembrane transport|sperm capacitation|intracellular pH elevation|transmembrane transport|membrane hyperpolarization|cellular response to cAMP|chloride transmembrane transport|,protein binding|secondary active sulfate transmembrane transporter activity|bicarbonate transmembrane transporter activity|chloride transmembrane transporter activity|sulfate transmembrane transporter activity|antiporter activity|anion:anion antiporter activity|anion:anion antiporter activity|,10,1.2,10.1,10,0.4,1.99,1,10.9,10.9,0.126,0,0,0.3,1.9
ENSMUSG00000074817,PAPOLB,poly (A) polymerase beta (testis specific),nucleus|cytoplasm|endoplasmic reticulum|,"mRNA splicing, via spliceosome|termination of RNA polymerase II transcription|mRNA polyadenylation|mRNA processing|RNA 3'-end processing|RNA polyadenylation|",nucleotide binding|RNA binding|polynucleotide adenylyltransferase activity|polynucleotide adenylyltransferase activity|polynucleotide adenylyltransferase activity|protein binding|ATP binding|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,1.2,14.1,10,-0.3,1.47,1.2,10.9,10.9,0.126,0,0,0.3,1.9
ENSMUSG00000055204,ANKRD17,ankyrin repeat domain 17,nucleus|cytoplasm|membrane|,blood vessel maturation|endoderm development|negative regulation of smooth muscle cell differentiation|,RNA binding|poly(A) RNA binding|,10,1.1,11.5,10,-0.7,1.93,0.4,10.8,10.8,0.127,0,0,0.2,1.8
ENSMUSG00000030521,MPHOSPH10,M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein),nucleus|chromosome|nucleolus|ribonucleoprotein complex|,rRNA processing|negative regulation of phosphatase activity|ribosome biogenesis|,poly(A) RNA binding|,9,0.8,10.5,8,-0.5,1.8,0.9,10.8,10.8,0.127,0,0,0.3,1.8
ENSMUSG00000039200,ATF7IP2,activating transcription factor 7 interacting protein 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,10,0.8,7.47,10,0.7,3.65,0.7,10.7,10.7,0.128,0,0,0.2,1.4
ENSMUSG00000045248,MED26,mediator complex subunit 26,nucleus|mediator complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|DNA binding|protein binding|,8,1,6.37,8,0.9,4.53,0.9,10.5,10.5,0.131,0,0,0.3,1.7
ENSMUSG00000027787,NMD3,NMD3 homolog (S. cerevisiae),nucleus|nucleoplasm|nucleolus|cytoplasm|membrane|,ribosomal large subunit export from nucleus|transport|protein transport|,"protein binding, bridging|ribosomal large subunit binding|poly(A) RNA binding|",10,-0.9,11.3,10,0,0,-0.9,10.5,-10.5,0.131,0,0,-1.8,-0.3
ENSMUSG00000027714,EXOSC9,exosome component 9,nuclear exosome (RNase complex)|exosome (RNase complex)|nucleus|nucleolus|cytoplasm|intermediate filament cytoskeleton|,nuclear-transcribed mRNA catabolic process|rRNA processing|positive regulation of cell growth|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|nuclear mRNA surveillance|nuclear polyadenylation-dependent rRNA catabolic process|,RNA binding|nuclease activity|exonuclease activity|hydrolase activity|AU-rich element binding|poly(A) RNA binding|,8,1,10.1,8,0.9,0.485,0.9,10.4,10.4,0.132,0,0,0.3,1.8
ENSMUSG00000024097,SRSF7,serine/arginine-rich splicing factor 7,nucleus|cytoplasm|extracellular vesicular exosome|,"mRNA processing|transport|RNA splicing|negative regulation of mRNA splicing, via spliceosome|mRNA transport|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,6,0.6,1.21,5,1.2,10.4,0.9,10.3,10.3,0.134,0,0,0.5,1.9
ENSMUSG00000052435,CEBPE,"CCAAT/enhancer binding protein (C/EBP), epsilon",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|phagocytosis|positive regulation of gene expression|macrophage differentiation|cytokine biosynthetic process|defense response to bacterium|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|protein heterodimerization activity|,10,0.5,5.49,10,0.6,5.08,0.6,10.1,10.1,0.136,0,0,0.2,1.1
ENSMUSG00000028330,NCBP1,nuclear cap binding protein subunit 1,nucleus|cytoplasm|mitochondrion|mRNA cap binding complex|nuclear cap binding complex|plasma membrane|ribonucleoprotein complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|7-methylguanosine mRNA capping|mRNA cleavage|mRNA processing|mRNA export from nucleus|regulation of translation|regulation of translational initiation|transport|RNA splicing|RNA metabolic process|gene silencing by RNA|positive regulation of mRNA 3'-end processing|mRNA cis splicing, via spliceosome|mRNA transport|",RNA cap binding|RNA binding|protein binding|poly(A) RNA binding|,8,-0.9,9.65,8,-0.4,1.43,-0.7,10.1,-10.1,0.136,0,0,-1.6,-0.3
ENSMUSG00000027230,CREB3L1,cAMP responsive element binding protein 3-like 1,nucleus|endoplasmic reticulum|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|response to unfolded protein|regulation of bone mineralization|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,9,1,5.67,9,2.1,6.99,2,9.95,9.95,0.139,0,0,0.9,4
ENSMUSG00000048878,HEXIM1,hexamethylene bis-acetamide inducible 1,nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",cyclin-dependent protein serine/threonine kinase inhibitor activity|protein binding|snRNA binding|,10,-0.4,3.74,10,-0.8,7.45,-0.6,9.86,-9.86,0.14,0,0,-1.2,-0.2
ENSMUSG00000010205,RAVER1,"ribonucleoprotein, PTB-binding 1",nucleus|cytoplasm|,None,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,8,-0.1,0.522,9,-1,11.2,-0.8,9.69,-9.69,0.142,0,0,-1.7,-0.3
ENSMUSG00000060121,GEMIN2,gem (nuclear organelle) associated protein 2,intracellular|nucleus|nucleus|spliceosomal complex|nucleolus|cytoplasm|cytoplasm|cytosol|SMN complex|SMN-Sm protein complex|,"spliceosomal complex assembly|spliceosomal snRNP assembly|mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",None,9,-0.8,11,9,-0.1,0.0868,-0.7,9.67,-9.67,0.142,0,0,-1.6,-0.2
ENSMUSG00000028322,EXOSC3,exosome component 3,nuclear exosome (RNase complex)|cytoplasmic exosome (RNase complex)|exosome (RNase complex)|nucleus|nucleolus|cytoplasm|transcriptionally active chromatin|,rRNA processing|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|DNA deamination|isotype switching|positive regulation of isotype switching|CUT catabolic process|,3'-5'-exoribonuclease activity|molecular_function|RNA binding|nuclease activity|exonuclease activity|5'-3' exoribonuclease activity|hydrolase activity|,9,-0.8,5.75,9,-0.9,4.21,-0.9,9.59,-9.59,0.143,0,0,-1.8,-0.3
ENSMUSG00000034762,GLIS1,GLIS family zinc finger 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|metal ion binding|,9,1,4.16,10,1.2,5.66,1.1,9.37,9.37,0.147,0,0,-0.4,2
ENSMUSG00000024215,SPDEF,SAM pointed domain containing ets transcription factor,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of cell fate commitment|positive regulation of cell fate commitment|positive regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|lung goblet cell differentiation|intestinal epithelial cell development|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,1.5,12.6,10,-0.1,0.205,1.5,9.25,9.25,0.149,0,0,0.6,2.8
ENSMUSG00000047603,ZFP235,zinc finger protein 235,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,1.6,12.6,10,-0.1,0.148,1.5,9.24,9.24,0.149,0,0,0.8,3
ENSMUSG00000003680,TAF6L,"TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor",nucleus|STAGA complex|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|histone H3 acetylation|regulation of sequence-specific DNA binding transcription factor activity|regulation of RNA biosynthetic process|",transcription coactivator activity|histone acetyltransferase activity|protein heterodimerization activity|,10,-0.7,8.1,10,-1.2,2.34,-1,9.23,-9.23,0.149,0,0,-1.8,-0.3
ENSMUSG00000034621,GPATCH8,G patch domain containing 8,None,biological_process|,nucleic acid binding|protein binding|poly(A) RNA binding|metal ion binding|,10,-0.4,3.31,10,-0.6,6.55,-0.6,9.16,-9.16,0.15,0,0,-1.3,-0.2
ENSMUSG00000021366,HIVEP1,human immunodeficiency virus type I enhancer binding protein 1,nucleus|nucleus|mitochondrion|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|DNA binding|protein binding|metal ion binding|HMG box domain binding|,10,0.7,3.47,10,0.5,6.3,0.5,9.15,9.15,0.15,0,0,0.2,1.1
ENSMUSG00000026174,RQCD1,rcd1 (required for cell differentiation) homolog 1 (S. pombe),cytoplasmic mRNA processing body|nucleus|cytoplasm|membrane|CCR4-NOT complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|cytokine-mediated signaling pathway|gene silencing by RNA|negative regulation of intracellular estrogen receptor signaling pathway|positive regulation of ligand-dependent nuclear receptor transcription coactivator activity|",protein binding|,10,1,11.5,10,-0.6,7.62,1,9.02,9.02,0.152,0,0,-0.9,2
ENSMUSG00000053801,GRWD1,glutamate-rich WD repeat containing 1,nucleus|nucleolus|cytoplasm|,biological_process|,poly(A) RNA binding|,9,0.6,2.75,9,0.8,6.58,0.7,8.9,8.9,0.154,0,0,0.3,1.6
ENSMUSG00000028837,PSMB2,"proteasome (prosome, macropain) subunit, beta type 2",proteasome complex|nucleus|cytoplasm|proteasome core complex|membrane|extracellular vesicular exosome|,proteolysis|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,4,0.3,0.564,4,-1.5,10.3,-1.5,8.74,-8.74,0.157,0,0,-3,-0.3
ENSMUSG00000046351,ZFP322A,zinc finger protein 322A,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.6,5.68,10,-0.4,3.84,-0.5,8.7,-8.7,0.158,0,0,-1.3,-0.2
ENSMUSG00000020526,ZNHIT3,"zinc finger, HIT type 3",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.7,11.7,10,-0.5,6.69,0.7,8.7,8.7,0.158,0,0,-0.6,2
ENSMUSG00000075394,HOXC4,homeobox C4,nucleus|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|embryonic organ morphogenesis|cartilage development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|HMG box domain binding|,10,0.7,11.1,10,-0.1,0.216,0.6,8.69,8.69,0.158,0,0,0.2,1.8
ENSMUSG00000047591,MAFA,"v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)",nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|nitric oxide mediated signal transduction|response to glucose|insulin secretion|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,9,0.9,7.55,10,0.3,2.72,0.6,8.66,8.66,0.158,0,0,0.2,1.5
ENSMUSG00000037876,JMJD1C,jumonji domain containing 1C,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|oxidation-reduction process|","sulfonate dioxygenase activity|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.5,2.36,10,0.6,6.84,0.6,8.64,8.64,0.158,0,0,0.2,1.5
ENSMUSG00000004846,PLOD3,"procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3",endoplasmic reticulum|membrane|extracellular vesicular exosome|,in utero embryonic development|endothelial cell morphogenesis|protein localization|neural tube development|collagen fibril organization|vasodilation|epidermis morphogenesis|oxidation-reduction process|lung morphogenesis|basement membrane assembly|,"iron ion binding|procollagen-lysine 5-dioxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|L-ascorbic acid binding|procollagen glucosyltransferase activity|metal ion binding|dioxygenase activity|",10,-0.2,1.22,10,-0.6,8.26,-0.5,8.53,-8.53,0.16,0,0,-1.2,-0.2
ENSMUSG00000024240,EPC1,enhancer of polycomb homolog 1 (Drosophila),nucleus|nucleus|nucleoplasm|nuclear membrane|Piccolo NuA4 histone acetyltransferase complex|NuA4 histone acetyltransferase complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|regulation of growth|histone H4 acetylation|histone H2A acetylation|negative regulation of gene expression, epigenetic|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of striated muscle cell differentiation|",histone acetyltransferase activity|,10,0.4,2.9,10,0.6,6.19,0.5,8.52,8.52,0.16,0,0,0.2,1.2
ENSMUSG00000003154,FOXJ2,forkhead box J2,nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.8,8.77,10,-0.1,0.559,-0.8,8.52,-8.52,0.16,0,0,-1.8,-0.3
ENSMUSG00000050966,LIN28A,lin-28 homolog A (C. elegans),cytoplasmic mRNA processing body|nucleus|nucleolus|cytoplasm|cytoplasm|cytoplasmic stress granule|,"regulation of transcription, DNA-templated|germ cell development|germ cell development|miRNA metabolic process|miRNA catabolic process|miRNA catabolic process|stem cell maintenance|gene silencing by RNA|pre-miRNA processing|pre-miRNA processing|pre-miRNA processing|RNA 3'-end processing|positive regulation of neuron differentiation|negative regulation of glial cell differentiation|positive regulation of translation|stem cell differentiation|regulation of gene silencing by miRNA|",nucleic acid binding|DNA binding|RNA binding|RNA binding|mRNA binding|zinc ion binding|translation initiation factor binding|miRNA binding|metal ion binding|,10,1,10.9,10,-0.1,0.121,1,8.43,8.43,0.162,0,0,0.2,1.8
ENSMUSG00000031585,GTF2E2,"general transcription factor II E, polypeptide 2 (beta subunit)",nucleus|transcription factor TFIIE complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|",DNA binding|protein binding|poly(A) RNA binding|,8,0.8,9.9,7,-0.6,3.37,0.7,8.38,8.38,0.163,0,0,0.2,2
ENSMUSG00000050188,LSM10,U7 snRNP-specific Sm-like protein LSM10,nucleus|U7 snRNP|Cajal body|ribonucleoprotein complex|,mitotic S phase|mRNA processing|RNA splicing|,RNA binding|snRNA binding|histone pre-mRNA DCP binding|,9,-1,8.6,9,0.2,0.484,-1,8.35,-8.35,0.163,0,0,-2,-0.4
ENSMUSG00000022718,DGCR8,DiGeorge syndrome critical region gene 8,nucleus|cytoplasm|microtubule cytoskeleton|,primary miRNA processing|,RNA binding|double-stranded RNA binding|metal ion binding|,9,-0.6,3.99,10,-0.7,4.68,-0.7,8.23,-8.23,0.165,0,0,-1.9,-0.1
ENSMUSG00000020262,ADARB1,"adenosine deaminase, RNA-specific, B1",nucleus|nucleus|nucleoplasm|nucleolus|,adenosine to inosine editing|adenosine to inosine editing|RNA processing|RNA processing|mRNA processing|negative regulation of cell proliferation|mRNA modification|negative regulation of cell migration|negative regulation of protein kinase activity by regulation of protein phosphorylation|positive regulation of viral genome replication|regulation of cell cycle|,RNA binding|RNA binding|double-stranded RNA binding|double-stranded RNA binding|double-stranded RNA adenosine deaminase activity|double-stranded RNA adenosine deaminase activity|adenosine deaminase activity|hydrolase activity|poly(A) RNA binding|metal ion binding|,10,1,3.67,10,0.5,5.51,0.6,8.22,8.22,0.166,0,0,0.2,1.6
ENSMUSG00000028675,PNRC2,proline-rich nuclear receptor coactivator 2,cytoplasmic mRNA processing body|nucleus|cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|transcription, DNA-templated|regulation of transcription, DNA-templated|",None,10,1.6,11.4,10,-0.2,0.309,1.5,8.22,8.22,0.166,0,0,0.7,3
ENSMUSG00000040725,HNRNPUL1,heterogeneous nuclear ribonucleoprotein U-like 1,nucleus|ribonucleoprotein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|RNA processing|response to virus|",nucleic acid binding|RNA binding|enzyme binding|poly(A) RNA binding|,10,-0.3,0.0618,10,0.8,10.8,0.8,8.18,8.18,0.166,0,0,0.3,1.8
ENSMUSG00000023087,CCRN4L,CCR4 carbon catabolite repression 4-like (S. cerevisiae),cytoplasmic mRNA processing body|nucleus|cytoplasm|perinuclear region of cytoplasm|,"deadenylation-dependent decapping of nuclear-transcribed mRNA|mRNA processing|response to extracellular stimulus|negative regulation of gene expression|response to lipopolysaccharide|circadian regulation of gene expression|cytoplasmic mRNA processing body assembly|regulation of circadian rhythm|positive regulation of fat cell differentiation|negative regulation of osteoblast differentiation|regulation of embryonic development|mRNA stabilization|rhythmic process|RNA phosphodiester bond hydrolysis, exonucleolytic|",RNA binding|mRNA binding|nuclease activity|exonuclease activity|poly(A)-specific ribonuclease activity|poly(A)-specific ribonuclease activity|protein binding|hydrolase activity|metal ion binding|,10,1.2,10.9,10,0.1,0.0353,1.2,8.14,8.14,0.167,0,0,0.3,2
ENSMUSG00000096210,H1F0,"H1 histone family, member 0",nucleosome|nuclear chromatin|nucleus|nucleus|chromosome|nuclear euchromatin|Golgi apparatus|actin cytoskeleton|,nucleosome assembly|,DNA binding|chromatin DNA binding|poly(A) RNA binding|,10,0.5,0.815,10,0.8,8.32,0.7,8.1,8.1,0.168,0,0,0.2,1.6
ENSMUSG00000020100,SLC29A3,"solute carrier family 29 (nucleoside transporters), member 3",lysosome|lysosomal membrane|endosome|membrane|integral component of membrane|,transport|nucleoside transport|nucleoside transmembrane transport|,nucleoside transmembrane transporter activity|,10,-0.4,0.327,10,-1.4,8.49,-0.5,7.98,-7.98,0.17,0,0,-2.5,-0.1
ENSMUSG00000016921,SRSF6,serine/arginine-rich splicing factor 6,nucleus|nuclear speck|,"alternative mRNA splicing, via spliceosome|regulation of alternative mRNA splicing, via spliceosome|mRNA splice site selection|mRNA processing|RNA splicing|regulation of keratinocyte proliferation|negative regulation of keratinocyte differentiation|negative regulation of mRNA splicing, via spliceosome|positive regulation of epithelial cell proliferation involved in lung morphogenesis|negative regulation of cell death|regulation of wound healing|",nucleotide binding|nucleic acid binding|RNA binding|pre-mRNA binding|poly(A) RNA binding|,10,0.3,3.03,10,0.6,5.87,0.4,7.87,7.87,0.172,0,0,0.1,1.1
ENSMUSG00000039523,CEP104,centrosomal protein 104,cytoplasm|centriole|cytoskeleton|,biological_process|,glycine binding|glycine binding|glutamate binding|glutamate binding|thienylcyclohexylpiperidine binding|thienylcyclohexylpiperidine binding|,10,0.9,10.7,10,-0.3,0.673,0.8,7.85,7.85,0.172,0,0,0.2,1.8
ENSMUSG00000049421,ZFP260,zinc finger protein 260,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.9,1.12,10,1.6,8.04,1.5,7.82,7.82,0.172,0,0,0.5,3
ENSMUSG00000039706,LDB2,LIM domain binding 2,nucleus|transcription factor complex|,hair follicle development|epithelial structure maintenance|somatic stem cell maintenance|positive regulation of cellular component biogenesis|positive regulation of transcription from RNA polymerase II promoter|regulation of RNA biosynthetic process|,transcription factor binding transcription factor activity|transcription cofactor activity|protein binding|enzyme binding|LIM domain binding|,10,0.4,1.66,10,0.9,7.84,0.6,7.78,7.78,0.173,0,0,0.1,1.6
ENSMUSG00000005883,SPO11,SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae),"chromosome, telomeric region|nucleus|chromosome|","DNA catabolic process, endonucleolytic|ovarian follicle development|DNA metabolic process|meiotic nuclear division|synapsis|reciprocal meiotic recombination|male meiosis I|spermatid development|protein localization to chromosome|",DNA binding|catalytic activity|ATP binding|hydrolase activity|,8,0.5,3.34,8,0.7,4.92,0.7,7.76,7.76,0.174,0,0,0.2,1.6
ENSMUSG00000035266,HELQ,"helicase, POLQ-like",nucleus|single-stranded DNA-dependent ATP-dependent DNA helicase complex|,double-strand break repair via homologous recombination|ATP catabolic process|DNA metabolic process|DNA duplex unwinding|,nucleotide binding|nucleic acid binding|helicase activity|ATP binding|hydrolase activity|single-stranded DNA-dependent ATP-dependent DNA helicase activity|,10,-1,10.6,10,0,0,-0.9,7.75,-7.75,0.174,0,0,-2,-0.3
ENSMUSG00000037993,DHX38,DEAH (Asp-Glu-Ala-His) box polypeptide 38,membrane|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|",nucleotide binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,-0.8,4.75,10,-0.6,3.39,-0.7,7.62,-7.62,0.176,0,0,-1.6,-0.2
ENSMUSG00000009569,MKL2,MKL/myocardin-like 2,nucleus|cytoplasm|,"in utero embryonic development|liver development|heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|heart development|muscle organ development|gene expression|regulation of gene expression|cell differentiation|positive regulation of striated muscle tissue development|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|blood vessel morphogenesis|embryonic organ development|cardiac muscle tissue development|smooth muscle cell differentiation|",nucleic acid binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription coactivator activity|actin binding|protein binding|,10,0.3,0.9,10,0.7,7.64,0.7,7.62,7.62,0.176,0,0,0.1,1.4
ENSMUSG00000040629,MAEL,maelstrom homolog (Drosophila),chromatin|XY body|intracellular|nucleus|cytoplasm|autosome|chromatoid body|P granule|perinuclear region of cytoplasm|piP-body|,negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|cellular response to DNA damage stimulus|meiotic nuclear division|synapsis|male meiosis|multicellular organismal development|spermatogenesis|intrinsic apoptotic signaling pathway in response to DNA damage|fertilization|negative regulation of gene expression|cell differentiation|gene silencing by RNA|piRNA metabolic process|DNA methylation involved in gamete generation|negative regulation of apoptotic process|regulation of organ growth|,DNA binding|protein binding|,10,0,0,10,-1.4,10.8,-1.4,7.6,-7.6,0.176,0,0,-2.8,-0.3
ENSMUSG00000067455,HIST1H4J,"histone cluster 1, H4j",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,9,0.7,1.4,10,0.8,6.61,0.7,7.58,7.58,0.177,0,0,0.2,1.6
ENSMUSG00000030149,KLRK1,"killer cell lectin-like receptor subfamily K, member 1",plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,stimulatory C-type lectin receptor signaling pathway|immune system process|natural killer cell activation|natural killer cell activation|cell differentiation|positive regulation of interferon-gamma production|innate immune response|positive regulation of nitric oxide biosynthetic process|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|defense response to Gram-positive bacterium|cellular response to lipopolysaccharide|,protein binding|kinase binding|carbohydrate binding|MHC class Ib receptor activity|MHC class I protein binding|protein homodimerization activity|,10,0.2,0.393,10,1.3,9.11,0.7,7.52,7.52,0.178,0,0,0.1,2.5
ENSMUSG00000074886,GRK6,G protein-coupled receptor kinase 6,cytosol|plasma membrane|membrane|membrane|,desensitization of G-protein coupled receptor protein signaling pathway|protein phosphorylation|signal transduction|negative regulation of anion channel activity|Wnt signaling pathway|phosphorylation|termination of G-protein coupled receptor signaling pathway|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|G-protein coupled receptor kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-0.9,10.2,-0.9,7.51,-7.51,0.178,0,0,-1.8,-0.3
ENSMUSG00000033319,FEM1C,fem-1 homolog c (C.elegans),cellular_component|cytoplasm|,biological_process|,molecular_function|,10,-0.8,7.1,10,-0.7,0.646,-0.8,7.48,-7.48,0.179,0,0,-1.7,-0.2
ENSMUSG00000062329,CYTL1,cytokine-like 1,cellular_component|,chondrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|inner ear development|chondroitin sulfate proteoglycan biosynthetic process|positive regulation of sequence-specific DNA binding transcription factor activity|cartilage homeostasis|,None,10,-1.4,10.7,10,0,0,-1.1,7.44,-7.44,0.18,0,0,-2,-0.4
ENSMUSG00000060093,HIST1H4A,"histone cluster 1, H4a",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,8,0.5,3.28,8,-0.9,9.96,-0.9,7.4,-7.4,0.181,0,0,-2,0
ENSMUSG00000003382,ETV3,ets variant 3,nucleus|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0,0,10,0.5,9.31,0.5,7.37,7.37,0.181,0,0,0.1,1.2
ENSMUSG00000027583,ZBTB46,zinc finger and BTB domain containing 46,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of granulocyte differentiation|negative regulation of macrophage differentiation|negative regulation of monocyte differentiation|negative regulation of dendritic cell differentiation|positive regulation of dendritic cell differentiation|",nucleic acid binding|protein binding|metal ion binding|,10,0.7,5.42,10,0.5,2.52,0.6,7.36,7.36,0.182,0,0,0.1,1.4
ENSMUSG00000061601,PCLO,piccolo (presynaptic cytomatrix protein),intracellular|cell|cell junction|synapse|synapse|,cytoskeleton organization|synaptic vesicle targeting|regulation of exocytosis|cAMP-mediated signaling|insulin secretion|,calcium ion binding|protein binding|profilin binding|calcium-dependent phospholipid binding|metal ion binding|,10,1.1,7.09,10,0.4,1.27,0.5,7.14,7.14,0.186,0,0,0.1,1.8
ENSMUSG00000027309,4930402H24RIK,RIKEN cDNA 4930402H24 gene,cellular_component|,biological_process|,molecular_function|,9,-1.4,9.93,10,0,0,-1,7.13,-7.13,0.187,0,0,-2,-0.3
ENSMUSG00000030291,MED21,mediator complex subunit 21,nucleus|mediator complex|mediator complex|,"blastocyst development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|stem cell maintenance|positive regulation of transcription from RNA polymerase II promoter|",transcription coactivator activity|protein binding|,7,1,5.75,8,-1.2,9.3,-1.2,7.12,-7.12,0.187,0,0,-2,1.1
ENSMUSG00000003444,MED29,mediator complex subunit 29,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,10,-0.5,2.92,10,0.8,7.52,0.7,7.1,7.1,0.187,0,0,0.1,1.9
ENSMUSG00000079509,ZFX,zinc finger protein X-linked,nucleus|,"ovarian follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|germ cell development|spermatogenesis|fertilization|embryo development|post-embryonic development|death|multicellular organism growth|oocyte development|homeostasis of number of cells|parental behavior|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.6,1.55,10,-0.5,5.87,-0.5,7.04,-7.04,0.188,0,0,-1.3,0
ENSMUSG00000035597,PRPF39,PRP39 pre-mRNA processing factor 39 homolog (yeast),intracellular|nucleus|,RNA processing|mRNA processing|biological_process|RNA splicing|,molecular_function|,10,1.1,7.58,10,0.3,1.25,0.3,7.03,7.03,0.189,0,0,0.1,1.8
ENSMUSG00000039158,AKNA,AT-hook transcription factor,nucleus|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|,10,-0.2,1.32,10,-0.5,6.39,-0.4,6.96,-6.96,0.19,0,0,-1,-0.1
ENSMUSG00000062397,ZFP706,zinc finger protein 706,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.5,5.06,10,-0.5,2.14,-0.5,6.89,-6.89,0.192,0,0,-1.6,-0.1
ENSMUSG00000027133,NOP10,NOP10 ribonucleoprotein,cellular_component|nucleus|ribonucleoprotein complex|box H/ACA RNP complex|,pseudouridine synthesis|rRNA processing|biological_process|ribosome biogenesis|,molecular_function|snoRNA binding|,3,0.5,1.73,3,0.8,6.07,0.8,6.89,6.89,0.192,0,0,0.3,2
ENSMUSG00000021494,DDX41,DEAD (Asp-Glu-Ala-Asp) box polypeptide 41,nucleus|spliceosomal complex|endoplasmic reticulum|membrane|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|cellular response to interferon-beta|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|,nucleotide binding|nucleic acid binding|DNA binding|RNA binding|helicase activity|protein binding|ATP binding|zinc ion binding|hydrolase activity|poly(A) RNA binding|metal ion binding|,9,-0.9,5.33,9,1.3,6.37,1,6.78,6.78,0.195,0,0,-1.1,2
ENSMUSG00000009596,TAF7L,"TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|transcription factor TFIID complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription initiation from RNA polymerase II promoter|multicellular organismal development|spermatogenesis|spermatid development|cell differentiation|sperm motility|",protein binding|,10,-0.7,6.08,10,-0.5,1.05,-0.6,6.76,-6.76,0.195,0,0,-1.8,0.3
ENSMUSG00000025785,EXOSC7,exosome component 7,exosome (RNase complex)|nucleus|cytoplasm|,rRNA processing|,RNA binding|,8,0.6,2.84,7,1,4.49,0.7,6.74,6.74,0.196,0,0,-0.8,2
ENSMUSG00000018678,SP2,Sp2 transcription factor,nucleus|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organism growth|fibroblast proliferation|embryonic organ development|cardiovascular system development|",nucleic acid binding|DNA binding|histone deacetylase binding|metal ion binding|,10,-0.1,0.0474,10,-0.5,7.68,-0.5,6.73,-6.73,0.196,0,0,-1.1,-0.1
ENSMUSG00000017843,PPP2R5C,"protein phosphatase 2, regulatory subunit B', gamma","protein phosphatase type 2A complex|chromosome, centromeric region|nucleus|chromosome|",signal transduction|proteasome-mediated ubiquitin-dependent protein catabolic process|,protein binding|protein phosphatase type 2A regulator activity|,9,-0.7,7.54,10,-0.3,0.689,-0.6,6.63,-6.63,0.199,0,0,-1.5,-0.1
ENSMUSG00000016554,EIF3D,"eukaryotic translation initiation factor 3, subunit D","cytoplasm|eukaryotic translation initiation factor 3 complex|eukaryotic translation initiation factor 3 complex|membrane|eukaryotic translation initiation factor 3 complex, eIF3m|",formation of translation initiation complex|translation|translational initiation|,translation initiation factor activity|translation initiation factor activity|poly(A) RNA binding|,10,-0.6,3.71,9,0.6,3.62,-0.5,6.61,-6.61,0.199,0,0,-1.4,0.9
ENSMUSG00000021743,FEZF2,Fez family zinc finger 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|axon guidance|axonal fasciculation|locomotory behavior|negative regulation of cell proliferation|dendrite development|telencephalon development|telencephalon development|dentate gyrus development|forebrain anterior/posterior pattern specification|cerebral cortex GABAergic interneuron migration|cerebral cortex neuron differentiation|commitment of neuronal cell to specific neuron type in forebrain|commitment of neuronal cell to specific neuron type in forebrain|cell differentiation|forebrain development|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|nucleic acid binding|DNA binding|metal ion binding|,10,-1.4,9.4,10,-0.1,0.0372,-1,6.58,-6.58,0.2,0,0,-2,-0.3
ENSMUSG00000021464,ROR2,receptor tyrosine kinase-like orphan receptor 2,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,"skeletal system development|cartilage condensation|somitogenesis|protein phosphorylation|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|Wnt signaling pathway, calcium modulating pathway|JNK cascade|multicellular organismal development|negative regulation of cell proliferation|phosphorylation|peptidyl-tyrosine phosphorylation|cell differentiation|positive regulation of cell migration|embryonic genitalia morphogenesis|inner ear morphogenesis|positive regulation of transcription, DNA-templated|Wnt signaling pathway, planar cell polarity pathway|negative regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|","nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|frizzled binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Wnt-protein binding|Wnt-protein binding|",9,-0.8,7.51,9,0.8,3.61,-0.7,6.45,-6.45,0.203,0,0,-2,0.8
ENSMUSG00000026254,EIF4E2,eukaryotic translation initiation factor 4E member 2,cytoplasm|mRNA cap binding complex|,in utero embryonic development|translation|translational initiation|regulation of translation|negative regulation of translation|,RNA binding|translation initiation factor activity|ubiquitin protein ligase binding|poly(A) RNA binding|,10,0.3,1.95,10,0.6,5.43,0.5,6.41,6.41,0.204,0,0,0.1,1.5
ENSMUSG00000018425,DHX40,DEAH (Asp-Glu-Ala-His) box polypeptide 40,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|,10,-0.6,5.42,10,-0.3,1.86,-0.5,6.38,-6.38,0.205,0,0,-1.5,0
ENSMUSG00000001569,NOM1,nucleolar protein with MIF4G domain 1,nucleus|nucleolus|,None,RNA binding|poly(A) RNA binding|,7,-0.4,1.87,7,-1.5,7.47,-1.4,6.28,-6.28,0.208,0,0,-2.9,-0.2
ENSMUSG00000055148,KLF2,Kruppel-like factor 2 (lung),nucleus|,"cell morphogenesis|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of interleukin-6 production|erythrocyte homeostasis|multicellular organism growth|positive regulation of transcription from RNA polymerase II promoter in response to stress|regulation of gene expression, epigenetic|erythrocyte maturation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein metabolic process|Type I pneumocyte differentiation|cellular response to laminar fluid shear stress|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|metal ion binding|,10,0.3,1.32,10,0.5,5.64,0.5,6.27,6.27,0.208,0,0,0.1,1.2
ENSMUSG00000063800,PRPF38A,PRP38 pre-mRNA processing factor 38 (yeast) domain containing A,cellular_component|nucleus|spliceosomal complex|,mRNA processing|biological_process|RNA splicing|,poly(A) RNA binding|,9,1,5.33,9,0.4,1.82,0.5,6.23,6.23,0.209,0,0,0.1,1.8
ENSMUSG00000028759,HP1BP3,"heterochromatin protein 1, binding protein 3",nucleosome|nucleus|chromosome|,nucleosome assembly|,DNA binding|,10,-0.6,4.3,10,-0.3,2.73,-0.5,6.18,-6.18,0.211,0,0,-1.4,-0.1
ENSMUSG00000022774,NCBP2,nuclear cap binding protein subunit 2,nucleus|nucleoplasm|cytoplasm|mRNA cap binding complex|nuclear cap binding complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|7-methylguanosine mRNA capping|mRNA processing|regulation of translation|regulation of translational initiation|transport|RNA splicing|gene silencing by RNA|mRNA cis splicing, via spliceosome|mRNA transport|",nucleotide binding|RNA cap binding|RNA 7-methylguanosine cap binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,5,-0.8,7.87,7,1,6.05,-0.8,6.11,-6.11,0.213,0,0,-2,1.4
ENSMUSG00000042625,SAFB2,scaffold attachment factor B2,nucleus|cytoplasm|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleotide binding|nucleic acid binding|DNA binding|RNA binding|identical protein binding|poly(A) RNA binding|,10,1.1,7.88,10,-0.5,1.17,0.4,6.09,6.09,0.213,0,0,0.1,2
ENSMUSG00000038507,PARP12,"poly (ADP-ribose) polymerase family, member 12",cellular_component|nucleus|,biological_process|,NAD+ ADP-ribosyltransferase activity|transferase activity|poly(A) RNA binding|metal ion binding|,10,0.5,2.83,10,0.8,3.96,0.6,6.08,6.08,0.214,0,0,0.1,1.6
ENSMUSG00000020018,SNRPF,small nuclear ribonucleoprotein polypeptide F,nucleus|spliceosomal complex|U7 snRNP|U1 snRNP|U4 snRNP|U12-type spliceosomal complex|cytoplasm|cytosol|ribonucleoprotein complex|small nuclear ribonucleoprotein complex|methylosome|pICln-Sm protein complex|SMN-Sm protein complex|catalytic step 2 spliceosome|,spliceosomal snRNP assembly|RNA processing|mRNA processing|RNA splicing|,RNA binding|,1,0,0,2,-0.9,6.76,-0.9,6.08,-6.08,0.214,0,0,-2,-0.1
ENSMUSG00000070520,NDNL2,necdin-like 2,"chromosome, telomeric region|nucleus|chromosome|cytoplasm|Smc5-Smc6 complex|","DNA repair|DNA recombination|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|positive regulation of protein ubiquitination|regulation of growth|",protein binding|,7,0.8,7.49,5,-1.3,7.59,0.7,6.07,6.07,0.214,0,0,-1.8,2
ENSMUSG00000031433,RBM41,RNA binding motif protein 41,cellular_component|,biological_process|,nucleotide binding|molecular_function|nucleic acid binding|RNA binding|,9,-0.8,4.2,9,-0.4,3.15,-0.4,6.06,-6.06,0.214,0,0,-1.7,-0.1
ENSMUSG00000039789,ZFP597,zinc finger protein 597,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.8,2.84,10,0.7,3.44,0.7,5.96,5.96,0.217,0,0,0.1,1.7
ENSMUSG00000055313,PGBD1,piggyBac transposable element derived 1,cellular_component|,biological_process|,molecular_function|,10,1.1,7.16,10,-1,0.891,0.3,5.95,5.95,0.218,0,0,0.1,2
ENSMUSG00000054160,NKX2-4,NK2 homeobox 4,cellular_component|nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|",DNA binding|sequence-specific DNA binding|,10,0.3,1.75,10,0.5,4.92,0.5,5.94,5.94,0.218,0,0,0,1.4
ENSMUSG00000032396,DIS3L,DIS3 mitotic control homolog (S. cerevisiae)-like,cytoplasmic exosome (RNase complex)|exosome (RNase complex)|cytoplasm|,"rRNA catabolic process|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|RNA binding|nuclease activity|exonuclease activity|5'-3' exoribonuclease activity|hydrolase activity|enzyme binding|,10,-0.3,1.57,10,-0.5,4.8,-0.5,5.93,-5.93,0.218,0,0,-1.1,0
ENSMUSG00000034154,INO80,INO80 homolog (S. cerevisiae),nucleus|microtubule|Ino80 complex|,mitotic sister chromatid segregation|double-strand break repair via homologous recombination|ATP catabolic process|DNA repair|double-strand break repair|DNA recombination|chromatin remodeling|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|positive regulation of nuclear cell cycle DNA replication|positive regulation of cell growth|DNA duplex unwinding|cellular response to UV|positive regulation of transcription from RNA polymerase II promoter|spindle assembly|cell division|UV-damage excision repair|cellular response to ionizing radiation|regulation of G1/S transition of mitotic cell cycle|,"nucleotide binding|DNA binding|DNA helicase activity|actin binding|helicase activity|ATP binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|ATPase activity|alpha-tubulin binding|",10,2,2.59,10,-0.6,6.62,-0.6,5.9,-5.9,0.219,0,0,-1.9,2.4
ENSMUSG00000023007,PRPF40B,PRP40 pre-mRNA processing factor 40 homolog B (yeast),cellular_component|nucleus|,mRNA processing|biological_process|RNA splicing|,molecular_function|,10,-0.9,4.92,10,-0.4,2.48,-0.5,5.87,-5.87,0.22,0,0,-2,-0.1
ENSMUSG00000020706,FTSJ3,FtsJ homolog 3 (E. coli),nucleus|nucleolus|,RNA methylation|rRNA processing|biological_process|rRNA methylation|methylation|ribosome biogenesis|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.5,2.13,9,2.1,8.38,2,5.87,5.87,0.22,0,0,-1.1,4
ENSMUSG00000031697,ORC6,"origin recognition complex, subunit 6",origin recognition complex|nucleus|nuclear origin of replication recognition complex|membrane|,DNA replication|DNA-dependent DNA replication|,molecular_function|DNA binding|,10,-1,6.42,9,0.4,1.85,-0.9,5.84,-5.84,0.221,0,0,-2,1
ENSMUSG00000063808,GPATCH1,G patch domain containing 1,catalytic step 2 spliceosome|,biological_process|,molecular_function|nucleic acid binding|,10,0.4,0.77,10,0.9,6.23,0.7,5.82,5.82,0.222,0,0,0.1,1.8
ENSMUSG00000016503,GTF3A,general transcription factor III A,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA binding|metal ion binding|,9,0.5,2.19,9,0.7,3.93,0.6,5.79,5.79,0.223,0,0,-0.3,1.7
ENSMUSG00000029068,CCNL2,cyclin L2,nucleus|,"regulation of cyclin-dependent protein serine/threonine kinase activity|transcription, DNA-templated|regulation of transcription, DNA-templated|RNA processing|biological_process|",protein binding|protein kinase binding|,9,-0.3,0.19,9,-0.7,6.53,-0.6,5.71,-5.71,0.226,0,0,-1.7,-0.1
ENSMUSG00000061013,MKX,mohawk homeobox,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|tendon sheath development|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|regulation of gene expression|positive regulation of gene expression|collagen fibril organization|positive regulation of collagen biosynthetic process|tendon cell differentiation|tendon formation|negative regulation of myoblast differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor binding|DNA binding|protein binding|sequence-specific DNA binding|,10,0.8,3.59,10,0.6,2.59,0.7,5.57,5.57,0.23,0,0,-0.1,1.7
ENSMUSG00000020246,HCFC2,host cell factor C2,nucleus|cytoplasm|plasma membrane|,negative regulation of transcription from RNA polymerase II promoter|,molecular_function|,10,-0.6,5.33,10,-0.2,1.38,-0.3,5.41,-5.41,0.236,0,0,-1.6,0.2
ENSMUSG00000053914,KDM4D,lysine (K)-specific demethylase 4D,nucleus|blood microparticle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H3-K9 demethylation|oxidation-reduction process|","sulfonate dioxygenase activity|molecular_function|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.4,3.42,10,-0.8,2.83,-0.6,5.39,-5.39,0.237,0,0,-1.4,0
ENSMUSG00000018750,ZBTB4,zinc finger and BTB domain containing 4,nucleus|,"cellular response to DNA damage stimulus|negative regulation of transcription, DNA-templated|",methyl-CpG binding|methyl-CpNpG binding|protein kinase binding|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|,10,1,7.53,10,-0.2,0.547,0.4,5.39,5.39,0.237,0,0,0.1,1.9
ENSMUSG00000038502,PTOV1,prostate tumor over expressed gene 1,nucleus|cytoplasm|plasma membrane|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",None,10,-0.7,3.46,10,-0.3,2.88,-0.4,5.38,-5.38,0.237,0,0,-1.6,0
ENSMUSG00000042390,GATAD2B,GATA zinc finger domain containing 2B,nuclear chromatin|nucleus|protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|ATP-dependent chromatin remodeling|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|nucleosomal DNA binding|sequence-specific DNA binding|metal ion binding|,10,-0.4,2.26,10,-0.4,3.26,-0.4,5.23,-5.23,0.243,0,0,-1.2,0.1
ENSMUSG00000019984,MED23,mediator complex subunit 23,nucleus|transcription factor complex|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",None,10,0.1,0.0566,10,0.4,5.68,0.4,5.22,5.22,0.243,0,0,-0.1,1.2
ENSMUSG00000038418,EGR1,early growth response 1,nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|learning or memory|response to glucose|positive regulation of gene expression|positive regulation of cell death|T cell differentiation|BMP signaling pathway|response to insulin|regulation of protein sumoylation|skeletal muscle cell differentiation|negative regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of long-term neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|interleukin-1-mediated signaling pathway|cellular response to organic substance|cellular response to cAMP|cellular response to gonadotropin stimulus|cellular response to gamma radiation|cellular response to heparin|cellular response to mycophenolic acid|glomerular mesangial cell proliferation|positive regulation of glomerular metanephric mesangial cell proliferation|negative regulation of canonical Wnt signaling pathway|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription factor binding|histone acetyltransferase binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,0.7,5.94,10,0.1,0.0933,0.5,5.2,5.2,0.244,0,0,-0.1,1.8
ENSMUSG00000020902,NTN1,netrin 1,extracellular region|proteinaceous extracellular matrix|basement membrane|cytoplasm|cell periphery|,neuron migration|apoptotic process|axonogenesis|axon guidance|axon guidance|positive regulation of cell proliferation|single organismal cell-cell adhesion|regulation of cell migration|regulation of cell migration|negative regulation of axon extension|mammary gland development|anterior/posterior axon guidance|establishment of nucleus localization|inner ear morphogenesis|positive regulation of axon extension|mammary gland duct morphogenesis|,protein binding|,10,1.6,8.64,10,-0.5,0.168,1.6,5.18,5.18,0.244,0,0,0.7,3
ENSMUSG00000023015,RACGAP1,Rac GTPase-activating protein 1,intracellular|nucleus|cytoplasm|cytoskeleton|plasma membrane|membrane|midbody|extrinsic component of cytoplasmic side of plasma membrane|cytoplasmic vesicle|cleavage furrow|spindle midzone|extracellular vesicular exosome|mitotic spindle|centralspindlin complex|,"mitotic cytokinesis|actomyosin contractile ring assembly|transport|ion transport|cell cycle|cytokinesis, initiation of separation|signal transduction|multicellular organismal development|spermatogenesis|sulfate transport|embryo development|cell differentiation|positive regulation of cytokinesis|intracellular signal transduction|positive regulation of GTPase activity|spindle midzone assembly involved in mitosis|cell division|regulation of attachment of spindle microtubules to kinetochore|","GTPase activator activity|phosphatidylinositol-3,4,5-trisphosphate binding|microtubule binding|lipid binding|protein kinase binding|alpha-tubulin binding|gamma-tubulin binding|metal ion binding|beta-tubulin binding|",10,-0.3,1.44,10,-1.1,5.11,-0.4,5.17,-5.17,0.245,0,0,-2,0.6
ENSMUSG00000018102,HIST1H2BC,"histone cluster 1, H2bc",extracellular space|nucleus|extracellular vesicular exosome|,innate immune response in mucosa|antibacterial humoral response|defense response to Gram-positive bacterium|,molecular_function|,6,-0.8,5.65,5,0.9,5.01,-0.5,5.11,-5.11,0.247,0,0,-1.9,1.5
ENSMUSG00000036698,AGO2,argonaute RISC catalytic subunit 2,cytoplasmic mRNA processing body|cytoplasmic mRNA processing body|nucleus|cytoplasm|polysome|mRNA cap binding complex|membrane|RISC complex|ribonucleoprotein complex|micro-ribonucleoprotein complex|micro-ribonucleoprotein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA cleavage|regulation of translation|multicellular organismal development|post-embryonic development|cell differentiation|gene silencing by RNA|pre-miRNA processing|negative regulation of translation involved in gene silencing by miRNA|mRNA cleavage involved in gene silencing by miRNA|negative regulation of translational initiation|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|RNA phosphodiester bond hydrolysis, endonucleolytic|RNA phosphodiester bond hydrolysis, endonucleolytic|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|","RNA 7-methylguanosine cap binding|nucleic acid binding|RNA binding|mRNA binding|nuclease activity|endonuclease activity|endoribonuclease activity|endoribonuclease activity|protein binding|hydrolase activity|siRNA binding|siRNA binding|poly(A) RNA binding|metal ion binding|endoribonuclease activity, cleaving siRNA-paired mRNA|",9,-0.4,1.37,9,-0.5,4.06,-0.5,5.11,-5.11,0.247,0,0,-1.5,0.1
ENSMUSG00000041483,ZFP281,zinc finger protein 281,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|embryonic body morphogenesis|negative regulation of gene expression|cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|stem cell differentiation|",core promoter binding|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,10,-1.3,8.16,10,-0.1,0.113,-1,5.1,-5.1,0.248,0,0,-2,-0.2
ENSMUSG00000021175,CDCA7L,cell division cycle associated 7 like,nucleus|nucleus|nucleolus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|",None,10,-0.7,4.56,10,-0.4,1.08,-0.6,5.06,-5.06,0.249,0,0,-1.8,0
ENSMUSG00000058589,ANKS1B,ankyrin repeat and sterile alpha motif domain containing 1B,cellular_component|nucleus|cytoplasm|plasma membrane|membrane|cell junction|cell projection|synapse|postsynaptic membrane|,biological_process|,ephrin receptor binding|,10,-0.3,1.84,10,-0.5,3.55,-0.4,5.04,-5.04,0.25,0,0,-1.2,0.1
ENSMUSG00000075595,ZFP652,zinc finger protein 652,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,9,0.8,2.31,9,0.4,3.91,0.4,4.99,4.99,0.252,0,0,0,1.5
ENSMUSG00000033080,VSX1,visual system homeobox 1 homolog (zebrafish),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|visual perception|neuron maturation|neuron development|response to stimulus|retinal bipolar neuron differentiation|retinal bipolar neuron differentiation|",DNA binding|sequence-specific DNA binding|,10,-0.7,6.78,10,0.1,0.103,-0.6,4.74,-4.74,0.263,0,0,-1.7,0.1
ENSMUSG00000030232,AEBP2,AE binding protein 2,nucleus|ESC/E(Z) complex|ESC/E(Z) complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|chromatin modification|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|transcription corepressor activity|transcription corepressor activity|metal ion binding|,10,0.5,2.93,10,0.5,2.07,0.5,4.73,4.73,0.264,0,0,-0.1,1.5
ENSMUSG00000024774,ANKRD22,ankyrin repeat domain 22,cellular_component|,biological_process|,molecular_function|,10,-0.6,2.26,10,0.4,3.43,0.5,4.7,4.7,0.265,0,0,-1.1,1.4
ENSMUSG00000031917,NIP7,nuclear import 7 homolog (S. cerevisiae),cellular_component|nucleus|,biological_process|ribosome biogenesis|ribosome assembly|,RNA binding|poly(A) RNA binding|,6,0.5,1.46,7,1,3.84,0.7,4.68,4.68,0.266,0,0,0.1,2
ENSMUSG00000037730,MYNN,myoneurin,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.1,0.234,10,-0.7,5.87,-0.5,4.66,-4.66,0.267,0,0,-2,2.4
ENSMUSG00000078866,GM14420,predicted gene 14420,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,1,5,10,0.3,0.282,0.4,4.63,4.63,0.268,0,0,-0.1,2
ENSMUSG00000031965,TBX20,T-box 20,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|patterning of blood vessels|neuron migration|heart looping|embryonic heart tube morphogenesis|outflow tract septum morphogenesis|outflow tract septum morphogenesis|outflow tract morphogenesis|tricuspid valve development|aortic valve development|aortic valve morphogenesis|pulmonary valve formation|endocardial cushion morphogenesis|cardiac chamber formation|cardiac right ventricle morphogenesis|endocardial cushion formation|cardiac septum development|pericardium morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|muscle contraction|multicellular organismal development|blood circulation|cell proliferation|dorsal/ventral pattern formation|regulation of epithelial to mesenchymal transition|negative regulation of SMAD protein complex assembly|visceral motor neuron differentiation|embryonic heart tube development|embryonic heart tube development|foramen ovale closure|embryonic heart tube elongation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cardiac muscle tissue morphogenesis|positive regulation of cardiac muscle cell proliferation|atrial septum morphogenesis|pulmonary vein morphogenesis|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription factor binding|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription coactivator activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|,10,1.2,7.04,10,-0.4,0.322,0.3,4.63,4.63,0.268,0,0,0,2
ENSMUSG00000027569,MRGBP,MRG/MORF4L binding protein,nucleus|H4/H2A histone acetyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|chromatin modification|regulation of growth|",molecular_function|,10,0.5,1.73,10,-1.1,5.87,0.6,4.63,4.63,0.268,0,0,-1.6,1.6
ENSMUSG00000025917,COPS5,"COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)",nucleus|transcription factor complex|cytoplasm|synaptic vesicle|COP9 signalosome|COP9 signalosome|cell junction|cytoplasmic vesicle|synapse|,"protein deneddylation|regulation of transcription, DNA-templated|proteolysis|cullin deneddylation|protein deubiquitination|positive regulation of transcription from RNA polymerase II promoter|regulation of JNK cascade|regulation of cell cycle|exosomal secretion|",transcription coactivator activity|ubiquitin-specific protease activity|protein binding|peptidase activity|cysteine-type peptidase activity|metallopeptidase activity|hydrolase activity|metal ion binding|,10,1,3.29,10,0.3,1.87,0.3,4.59,4.59,0.27,0,0,-1.4,1.6
ENSMUSG00000026439,RBBP5,retinoblastoma binding protein 5,nucleus|nucleolus|histone methyltransferase complex|Set1C/COMPASS complex|MLL1 complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|chromatin modification|response to estrogen|histone H3-K4 methylation|histone H3-K4 methylation|",protein binding|methylated histone binding|histone methyltransferase activity (H3-K4 specific)|transcription regulatory region DNA binding|,9,1,3.07,8,-1.2,4.2,0.7,4.55,4.55,0.272,0,0,-1.5,1.9
ENSMUSG00000021431,SNRNP48,small nuclear ribonucleoprotein 48 (U11/U12),nucleus|spliceosomal complex|U12-type spliceosomal complex|,mRNA processing|biological_process|RNA splicing|,molecular_function|metal ion binding|,9,0.8,3.44,9,-0.6,3.21,0.9,4.54,4.54,0.273,0,0,-0.7,2
ENSMUSG00000056648,HOXB8,homeobox B8,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|grooming behavior|adult locomotory behavior|anterior/posterior pattern specification|anterior/posterior pattern specification|sensory perception of pain|dorsal spinal cord development|negative regulation of myeloid cell differentiation|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|skeletal system morphogenesis|skeletal system morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,1,4.31,10,0.3,0.466,0.4,4.48,4.48,0.275,0,0,-0.1,1.9
ENSMUSG00000002948,MAP2K7,mitogen-activated protein kinase kinase 7,nucleus|nucleus|cytoplasm|cytosol|,positive regulation of protein phosphorylation|protein phosphorylation|protein phosphorylation|apoptotic process|response to stress|response to stress|JNK cascade|activation of JUN kinase activity|activation of JUN kinase activity|phosphorylation|positive regulation of neuron apoptotic process|stress-activated MAPK cascade|stress-activated MAPK cascade|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|MAP kinase kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|protein C-terminus binding|JUN kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein phosphatase binding|mitogen-activated protein kinase kinase kinase binding|metal ion binding|",10,0.4,2.75,9,-0.7,7.25,-0.7,4.45,-4.45,0.277,0,0,-1.7,0.7
ENSMUSG00000035378,SHQ1,SHQ1 homolog (S. cerevisiae),nucleus|nucleoplasm|cytoplasm|,ribonucleoprotein complex assembly|positive regulation of apoptotic process|negative regulation of rRNA processing|,molecular_function|,9,-0.4,0.875,9,-0.6,4.13,-0.6,4.36,-4.36,0.281,0,0,-1.7,0.3
ENSMUSG00000069049,EIF2S3Y,"eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked",None,translation|translational initiation|,nucleotide binding|translation initiation factor activity|GTPase activity|GTP binding|,10,1.2,7.02,10,0,0,1.1,4.35,4.35,0.282,0,0,0.1,2
ENSMUSG00000021095,GSC,goosecoid homeobox,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|multicellular organismal development|anatomical structure morphogenesis|neural crest cell fate specification|dorsal/ventral neural tube patterning|signal transduction involved in regulation of gene expression|negative regulation of Wnt signaling pathway|forebrain development|middle ear morphogenesis|ear development|muscle organ morphogenesis|embryonic skeletal system morphogenesis|",RNA polymerase II transcription factor binding|RNA polymerase II repressing transcription factor binding|DNA binding|protein binding|sequence-specific DNA binding|,10,-0.6,3.77,10,-0.5,0.812,-0.6,4.3,-4.3,0.284,0,0,-1.6,1.6
ENSMUSG00000028898,TRNAU1AP,tRNA selenocysteine 1 associated protein 1,nucleus|cytoplasm|,selenocysteine incorporation|translation|,tRNA binding|nucleotide binding|nucleic acid binding|RNA binding|protein binding|poly(A) RNA binding|,10,-0.8,3.01,10,0.5,2.09,-1.2,4.29,-4.29,0.285,0,0,-2,0.5
ENSMUSG00000032940,RBM11,RNA binding motif protein 11,nucleus|nucleoplasm|nuclear speck|,"regulation of alternative mRNA splicing, via spliceosome|mRNA processing|multicellular organismal development|RNA splicing|cell differentiation|cellular response to oxidative stress|",nucleotide binding|nucleic acid binding|RNA binding|poly(U) RNA binding|poly(U) RNA binding|protein homodimerization activity|,10,0.4,1.64,10,-1,7.28,-1,4.29,-4.29,0.285,0,0,-2,0.5
ENSMUSG00000019947,ARID5B,AT rich interactive domain 5B (MRF1-like),intracellular|nucleus|,"kidney development|transcription, DNA-templated|regulation of transcription, DNA-templated|nitrogen compound metabolic process|male gonad development|female gonad development|post-embryonic development|fibroblast migration|adrenal gland development|multicellular organism growth|fat cell differentiation|platelet-derived growth factor receptor signaling pathway|cell development|muscle organ morphogenesis|skeletal system morphogenesis|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|palate development|face morphogenesis|adipose tissue development|fat pad development|",DNA binding|transcription coactivator activity|transcription regulatory region DNA binding|,10,0.5,2.83,10,0.5,1.61,0.5,4.19,4.19,0.29,0,0,-0.1,1.5
ENSMUSG00000066037,HNRNPR,heterogeneous nuclear ribonucleoprotein R,nucleus|nucleus|nucleoplasm|virion|viral nucleocapsid|ribonucleoprotein complex|catalytic step 2 spliceosome|,None,poly(A) RNA binding|,10,0,0,10,0.6,5.3,0.6,4.18,4.18,0.29,0,0,-0.1,1.7
ENSMUSG00000033983,COIL,coilin,female germ cell nucleus|nucleus|nucleoplasm|nucleolus|cytoplasm|Cajal body|Cajal body|membrane|,oxidation-reduction process|,protein binding|protein C-terminus binding|disulfide oxidoreductase activity|identical protein binding|,10,-0.8,2.56,9,0.4,2.13,0.4,4.17,4.17,0.291,0,0,-1.7,1.1
ENSMUSG00000046962,ZBTB21,zinc finger and BTB domain containing 21,nucleus|,"negative regulation of transcription, DNA-templated|",methyl-CpG binding|metal ion binding|,10,-0.5,3.11,10,-0.3,1.78,-0.4,4.17,-4.17,0.291,0,0,-1.4,0.3
ENSMUSG00000027566,PSMA7,"proteasome (prosome, macropain) subunit, alpha type 7","proteasome complex|nucleus|cytoplasm|proteasome core complex|proteasome core complex, alpha-subunit complex|extracellular vesicular exosome|",proteolysis|ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|identical protein binding|,6,-0.7,3.39,9,1.1,2.37,-0.5,4.16,-4.16,0.292,0,0,-1.7,1.5
ENSMUSG00000042472,ZFP410,zinc finger protein 410,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.4,1.21,10,-0.5,3.33,-0.4,4.15,-4.15,0.292,0,0,-1.4,0.2
ENSMUSG00000022623,SHANK3,SH3/ankyrin domain gene 3,intracellular|cytoplasm|plasma membrane|postsynaptic density|membrane|cell junction|cell projection|neuron projection|neuron spine|synapse|postsynaptic membrane|excitatory synapse|ciliary membrane|neuronal postsynaptic density|,"MAPK cascade|embryonic epithelial tube formation|synapse assembly|learning|learning|memory|striatal medium spiny neuron differentiation|adult behavior|negative regulation of actin filament bundle assembly|social behavior|social behavior|locomotory exploration behavior|vocal learning|negative regulation of cell volume|positive regulation of long-term neuronal synaptic plasticity|brain morphogenesis|neuromuscular process controlling balance|protein oligomerization|positive regulation of synapse structural plasticity|positive regulation of synaptic transmission, glutamatergic|dendritic spine morphogenesis|positive regulation of dendritic spine development|regulation of dendritic spine morphogenesis|vocalization behavior|vocalization behavior|postsynaptic density assembly|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|N-methyl-D-aspartate receptor clustering|guanylate kinase-associated protein clustering|regulation of long-term synaptic potentiation|positive regulation of glutamate receptor signaling pathway|positive regulation of glutamate receptor signaling pathway|regulation of long term synaptic depression|positive regulation of excitatory postsynaptic membrane potential|regulation of grooming behavior|regulation of behavioral fear response|positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|",actin binding|protein binding|protein C-terminus binding|protein C-terminus binding|zinc ion binding|SH3 domain binding|GKAP/Homer scaffold activity|ionotropic glutamate receptor binding|identical protein binding|protein self-association|scaffold protein binding|scaffold protein binding|,10,0.3,0.752,10,-0.4,4.52,-0.4,4.13,-4.13,0.293,0,0,-1.4,0.5
ENSMUSG00000015804,MED28,mediator complex subunit 28,nucleus|cytoplasm|cytoskeleton|membrane|mediator complex|cortical actin cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|stem cell maintenance|negative regulation of smooth muscle cell differentiation|",actin binding|protein binding|,10,-0.6,2.31,9,-0.4,2.38,-0.4,4.05,-4.05,0.298,0,0,-1.6,1.2
ENSMUSG00000048100,TAF13,"TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|nucleus|transcription factor TFIID complex|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|protein binding|protein C-terminus binding|protein heterodimerization activity|,10,1.1,6.58,9,-0.3,4.48,0.3,3.96,3.96,0.303,0,0,-0.4,2
ENSMUSG00000041390,MDFIC,MyoD family inhibitor domain containing,nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|Golgi apparatus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|activation of JUN kinase activity|regulation of Wnt signaling pathway|negative regulation of protein import into nucleus|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of viral transcription|",protein binding|transcription factor binding|cyclin binding|Tat protein binding|,10,1.7,7.24,10,-0.1,0.14,1.6,3.94,3.94,0.304,0,0,-0.1,3
ENSMUSG00000042726,TRAFD1,TRAF type zinc finger domain containing 1,cellular_component|,negative regulation of innate immune response|,protein binding|zinc ion binding|metal ion binding|,10,0.3,0.536,10,0.6,3.9,0.5,3.93,3.93,0.304,0,0,-0.1,1.6
ENSMUSG00000033543,GTF2A2,"general transcription factor II A, 2",nucleus|transcription factor TFIIA complex|cell junction|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of sequence-specific DNA binding transcription factor activity|RNA polymerase II transcriptional preinitiation complex assembly|",RNA polymerase II repressing transcription factor binding|transcription coactivator activity|transcription factor binding|TBP-class protein binding|protein homodimerization activity|protein heterodimerization activity|,10,-0.7,4.41,10,0.4,0.697,-0.7,3.86,-3.86,0.308,0,0,-1.8,0.8
ENSMUSG00000028059,ARHGEF2,rho/rac guanine nucleotide exchange factor (GEF) 2,cell|cytoplasm|Golgi apparatus|cytoskeleton|microtubule|tight junction|cell junction|cytoplasmic vesicle|vesicle|ruffle membrane|neuronal cell body|dendritic shaft|protein complex|,establishment of mitotic spindle orientation|cell morphogenesis|cell morphogenesis|immune system process|actin filament organization|actin filament organization|negative regulation of microtubule depolymerization|cell cycle|mitotic nuclear division|positive regulation of Rho GTPase activity|positive regulation of Rho GTPase activity|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|innate immune response|positive regulation of transcription from RNA polymerase II promoter|positive regulation of peptidyl-tyrosine phosphorylation|negative regulation of neurogenesis|positive regulation of NF-kappaB transcription factor activity|cell division|cellular response to muramyl dipeptide|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|microtubule binding|microtubule binding|Rho GTPase binding|Rac guanyl-nucleotide exchange factor activity|metal ion binding|Rac GTPase binding|,10,-0.2,0.475,10,-0.4,3.7,-0.3,3.85,-3.85,0.309,0,0,-1.4,0.2
ENSMUSG00000078851,HIST3H2A,"histone cluster 3, H2a",nucleosome|nuclear nucleosome|nucleus|chromosome|,nucleosome disassembly|UV-damage excision repair|,DNA binding|protein heterodimerization activity|,10,0.2,0.465,10,0.6,4.62,0.3,3.85,3.85,0.309,0,0,-0.2,1.5
ENSMUSG00000033454,ZBTB1,zinc finger and BTB domain containing 1,nucleus|nucleoplasm|nuclear body|,"negative regulation of transcription from RNA polymerase II promoter|immune system process|positive regulation of T cell mediated immunity|transcription, DNA-templated|regulation of transcription, DNA-templated|cell differentiation|B cell differentiation|positive regulation of natural killer cell differentiation|T cell differentiation in thymus|mRNA transcription from RNA polymerase II promoter|innate immune response|positive regulation of T cell differentiation|thymus development|protein homooligomerization|positive regulation of pro-T cell differentiation|",nucleic acid binding|DNA binding|protein binding|protein homodimerization activity|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,-0.3,2.21,10,-0.4,2.06,-0.3,3.85,-3.85,0.309,0,0,-1.3,0.3
ENSMUSG00000005846,RSL1D1,ribosomal L1 domain containing 1,nucleolus|nucleolus|membrane|,osteoblast differentiation|regulation of protein localization|,protein binding|poly(A) RNA binding|,9,1.7,6.88,7,0,0,1.7,3.83,3.83,0.31,0,0,-1.3,3
ENSMUSG00000054967,ZFP647,zinc finger protein 647,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,1.1,6.78,10,-0.9,0.389,0.3,3.82,3.82,0.311,0,0,-0.2,2
ENSMUSG00000038425,POLI,"polymerase (DNA directed), iota",intracellular|nucleus|intracellular membrane-bounded organelle|,DNA replication|DNA-dependent DNA replication|DNA repair|cellular response to DNA damage stimulus|DNA biosynthetic process|,DNA binding|damaged DNA binding|DNA-directed DNA polymerase activity|transferase activity|nucleotidyltransferase activity|metal ion binding|,10,-1,6.95,10,0.2,0.675,-1,3.8,-3.8,0.312,0,0,-2,0.7
ENSMUSG00000050600,ZFP831,zinc finger protein 831,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.67,10,-0.4,2.55,-0.4,3.79,-3.79,0.312,0,0,-1.3,0.7
ENSMUSG00000039699,BATF2,"basic leucine zipper transcription factor, ATF-like 2",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell differentiation|defense response to protozoan|myeloid dendritic cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.5,3.13,10,0.3,0.985,0.5,3.75,3.75,0.314,0,0,-0.6,1.4
ENSMUSG00000024186,RGS11,regulator of G-protein signaling 11,cytoplasm|heterotrimeric G-protein complex|plasma membrane|protein complex|dendrite terminus|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|intracellular signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,signal transducer activity|GTPase activator activity|GTPase activator activity|protein binding|G-protein beta-subunit binding|,10,0.4,1.84,10,0.3,2.19,0.4,3.74,3.74,0.315,0,0,-0.5,1.3
ENSMUSG00000039623,AP5Z1,"adaptor-related protein complex 5, zeta 1 subunit",nucleus|cytoplasm|AP-5 adaptor complex|,double-strand break repair via homologous recombination|DNA repair|transport|cellular response to DNA damage stimulus|protein transport|endosomal transport|,molecular_function|,10,2.1,1.77,10,0.8,5.47,1.2,3.71,3.71,0.317,0,0,0,3.4
ENSMUSG00000068749,PSMA5,"proteasome (prosome, macropain) subunit, alpha type 5","proteasome complex|nucleus|cytoplasm|proteasome core complex|proteasome core complex, alpha-subunit complex|extracellular vesicular exosome|",proteolysis|ubiquitin-dependent protein catabolic process|proteolysis involved in cellular protein catabolic process|,endopeptidase activity|threonine-type endopeptidase activity|peptidase activity|hydrolase activity|,7,-0.3,0.339,6,-0.5,3.97,-0.5,3.68,-3.68,0.319,0,0,-1.8,0.8
ENSMUSG00000051518,RPS19BP1,ribosomal protein S19 binding protein 1,nucleus|nucleoplasm|nucleolus|nucleolus|cytoplasm|,biological_process|,protein binding|enzyme binding|poly(A) RNA binding|,10,1.1,5.99,9,-1,1.6,0.6,3.61,3.61,0.323,0,0,-0.7,2
ENSMUSG00000041215,YEATS2,YEATS domain containing 2,nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|mitotic spindle|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|histone H3 acetylation|negative regulation of transcription, DNA-templated|",TBP-class protein binding|,10,0.5,4.04,10,0.1,0.135,0.4,3.6,3.6,0.324,0,0,-0.3,1.9
ENSMUSG00000021470,ERCC6L2,"excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2",cellular_component|nucleus|cytoplasm|mitochondrion|cytoskeleton|,DNA repair|cellular response to DNA damage stimulus|biological_process|,nucleotide binding|nucleic acid binding|DNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|,10,-0.4,2.78,10,-0.4,1.04,-0.4,3.6,-3.6,0.324,0,0,-1.6,0.5
ENSMUSG00000027613,EIF6,eukaryotic translation initiation factor 6,nucleus|lamin filament|cytoplasm|intermediate filament|extracellular vesicular exosome|,translation|translational initiation|integrin-mediated signaling pathway|ribosome biogenesis|mature ribosome assembly|,translation initiation factor activity|ribosome binding|,8,1,4.71,8,-1.1,5.83,-0.7,3.59,-3.59,0.324,0,0,-2,1.5
ENSMUSG00000033760,RBM4B,RNA binding motif protein 4B,cellular_component|nucleus|,mRNA processing|regulation of translation|circadian rhythm|RNA splicing|positive regulation of gene expression|circadian regulation of gene expression|entrainment of circadian clock by photoperiod|,nucleotide binding|nucleic acid binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.5,2.26,10,-0.4,1.73,-0.5,3.59,-3.59,0.324,0,0,-1.6,0.3
ENSMUSG00000027881,PRPF38B,PRP38 pre-mRNA processing factor 38 (yeast) domain containing B,cellular_component|nucleus|spliceosomal complex|,mRNA processing|biological_process|RNA splicing|,poly(A) RNA binding|,6,1.7,6.43,7,-0.3,0.661,1.7,3.56,3.56,0.326,0,0,-0.7,3
ENSMUSG00000020092,PALD1,"phosphatase domain containing, paladin 1",cytoplasm|cytosol|,biological_process|,molecular_function|,10,-0.7,1.2,10,-0.4,3.15,-0.4,3.55,-3.55,0.327,0,0,-1.7,0.2
ENSMUSG00000015882,LCORL,ligand dependent nuclear receptor corepressor-like,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",DNA binding|,10,-0.9,4.35,10,-0.3,1.06,-0.5,3.54,-3.54,0.328,0,0,-2,0.1
ENSMUSG00000047710,CHAMP1,chromosome alignment maintaining phosphoprotein 1,"chromosome, centromeric region|kinetochore|condensed chromosome kinetochore|condensed chromosome|nucleus|chromosome|cytoplasm|spindle|cytoskeleton|",sister chromatid biorientation|protein localization to kinetochore|protein localization to microtubule|attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|,nucleic acid binding|metal ion binding|,10,0.4,1.56,10,0.5,2.24,0.4,3.53,3.53,0.328,0,0,-0.3,1.5
ENSMUSG00000061911,MYT1L,myelin transcription factor 1-like,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription coactivator activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|retinoic acid-responsive element binding|metal ion binding|,10,-0.9,4.12,10,-0.3,0.698,-0.5,3.52,-3.52,0.329,0,0,-2,0
ENSMUSG00000057561,EIF1A,eukaryotic translation initiation factor 1A,None,translation|translational initiation|,RNA binding|translation initiation factor activity|poly(A) RNA binding|,10,1,6.06,10,0.1,0.186,0.9,3.52,3.52,0.329,0,0,0,2
ENSMUSG00000072437,NANOS1,nanos homolog 1 (Drosophila),cytoplasm|cytoplasm|perinuclear region of cytoplasm|,regulation of translation|epithelial cell migration|cell migration|,molecular_function|RNA binding|zinc ion binding|metal ion binding|,10,1,3.22,10,0.4,1.53,0.4,3.51,3.51,0.329,0,0,-0.4,2
ENSMUSG00000020871,DLX4,distal-less homeobox 4,cellular_component|nucleus|,"regulation of transcription, DNA-templated|multicellular organismal development|",DNA binding|sequence-specific DNA binding|,9,0,0,9,1.3,6.21,1,3.48,3.48,0.331,0,0,0,2
ENSMUSG00000006642,TCF23,transcription factor 23,nucleus|,multicellular organismal development|muscle organ development|cell differentiation|,protein dimerization activity|,10,1,2.23,10,0.6,1.73,0.6,3.47,3.47,0.332,0,0,-0.1,1.8
ENSMUSG00000033099,NOL12,nucleolar protein 12,nucleus|nucleolus|nucleolus|,biological_process|,RNA binding|rRNA binding|poly(A) RNA binding|,10,-1,6.23,10,0.9,2.95,-0.9,3.41,-3.41,0.336,0,0,-2,1.2
ENSMUSG00000027016,ZFP385B,zinc finger protein 385B,nucleus|,apoptotic process|intrinsic apoptotic signaling pathway by p53 class mediator|,p53 binding|nucleic acid binding|zinc ion binding|metal ion binding|,10,-0.6,2.41,10,-0.4,1.33,-0.5,3.37,-3.37,0.338,0,0,-1.7,0.2
ENSMUSG00000068302,NOTO,notochord homolog (Xenopus laevis),cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|determination of left/right symmetry|embryonic pattern specification|dorsal/ventral pattern formation|notochord development|cilium morphogenesis|",DNA binding|,10,0.4,0.869,10,0.4,2.71,0.4,3.37,3.37,0.338,0,0,-0.4,1.4
ENSMUSG00000032777,GTF3C1,general transcription factor III C 1,transcription factor TFIIIC complex|nucleus|nucleolus|membrane|ribonucleoprotein complex|,"transcription, DNA-templated|",DNA binding|,8,0.9,2.1,8,0.6,1.49,0.9,3.33,3.33,0.341,0,0,-0.4,2
ENSMUSG00000030243,RECQL,RecQ protein-like,nucleus|membrane|,DNA strand renaturation|DNA replication|DNA repair|DNA recombination|DNA duplex unwinding|,nucleotide binding|nucleic acid binding|DNA binding|DNA helicase activity|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|annealing helicase activity|ATP-dependent 3'-5' DNA helicase activity|,10,-0.3,0.391,10,-0.5,3.37,-0.4,3.33,-3.33,0.341,0,0,-1.5,0.4
ENSMUSG00000070732,RBM44,RNA binding motif protein 44,cytoplasm|intercellular bridge|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|protein binding|protein homodimerization activity|,10,-0.3,0.496,10,-0.6,3.44,-0.5,3.31,-3.31,0.342,0,0,-1.6,0.3
ENSMUSG00000035601,TRMT10B,tRNA methyltransferase 10B,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,0.9,3.12,9,0.2,1.37,0.3,3.3,3.3,0.343,0,0,-0.1,1.9
ENSMUSG00000032802,SRXN1,sulfiredoxin 1 homolog (S. cerevisiae),cytoplasm|cytosol|cytosol|,response to oxidative stress|response to oxidative stress|oxidation-reduction process|,"nucleotide binding|ATP binding|antioxidant activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors|oxidoreductase activity, acting on a sulfur group of donors|sulfiredoxin activity|",10,0.8,5.42,10,-0.5,1.09,0.6,3.23,3.23,0.348,0,0,-0.7,1.9
ENSMUSG00000029802,ABCG2,"ATP-binding cassette, sub-family G (WHITE), member 2",nucleus|mitochondrion|plasma membrane|membrane|integral component of membrane|apical plasma membrane|,transport|drug transmembrane transport|drug transport|urate metabolic process|drug export|embryonic process involved in female pregnancy|,nucleotide binding|ATP binding|drug transmembrane transporter activity|ATPase activity|protein homodimerization activity|protein dimerization activity|,10,-0.4,2.52,10,-0.5,0.961,-0.4,3.22,-3.22,0.349,0,0,-1.6,0.4
ENSMUSG00000097084,FOXL1,forkhead box L1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|visceral mesoderm-endoderm interaction involved in midgut development|heart development|regulation of Wnt signaling pathway|proteoglycan biosynthetic process|Peyer's patch morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,9,0,0,10,-1.5,6.21,-1.4,3.21,-3.21,0.349,0,0,-3,-0.1
ENSMUSG00000031374,ZFP92,zinc finger protein 92,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.9,1.57,10,0.3,1.91,0.3,3.2,3.2,0.35,0,0,-0.2,1.8
ENSMUSG00000063972,NR6A1,"nuclear receptor subfamily 6, group A, member 1",nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|cell differentiation|steroid hormone mediated signaling pathway|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|protein binding|zinc ion binding|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|,10,-0.4,2.51,10,-0.3,1.08,-0.4,3.19,-3.19,0.351,0,0,-1.6,0.3
ENSMUSG00000045273,CENPH,centromere protein H,"chromosome, centromeric region|kinetochore|kinetochore|kinetochore|nucleus|nucleus|chromosome|",chromosome segregation|mitotic nuclear division|kinetochore assembly|kinetochore organization|,kinetochore binding|kinetochore binding|,10,0.4,1.87,10,2,4.63,1.9,3.16,3.16,0.353,0,0,0,3.8
ENSMUSG00000020599,RGS9,regulator of G-protein signaling 9,nucleus|cytoplasm|cytoplasm|heterotrimeric G-protein complex|plasma membrane|membrane|,G-protein coupled receptor signaling pathway|dopamine receptor signaling pathway|visual perception|regulation of G-protein coupled receptor protein signaling pathway|negative regulation of signal transduction|intracellular signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|positive regulation of GTPase activity|response to stimulus|,signal transducer activity|GTPase activator activity|GTPase activator activity|GTPase activator activity|protein binding|protein complex binding|,10,0.3,1.03,10,-0.5,5.22,-0.4,3.15,-3.15,0.354,0,0,-1.6,0.7
ENSMUSG00000035310,LIN54,lin-54 homolog (C. elegans),cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|biological_process|",molecular_function|DNA binding|,10,-0.2,0.74,10,-0.6,3.76,-0.4,3.15,-3.15,0.354,0,0,-1.6,0.5
ENSMUSG00000056820,TSNAX,translin-associated factor X,nucleus|cytoplasm|Golgi apparatus|,multicellular organismal development|spermatogenesis|cell differentiation|,DNA binding|single-stranded DNA binding|protein binding|A2A adenosine receptor binding|protein complex binding|sequence-specific DNA binding|poly(A) RNA binding|metal ion binding|,10,-0.7,2.61,10,-0.3,1.25,-0.3,3.14,-3.14,0.354,0,0,-1.9,0.2
ENSMUSG00000019792,TRMT11,tRNA methyltransferase 11,cellular_component|,tRNA processing|methylation|,"tRNA binding|rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.3,1.51,10,-0.3,1.78,-0.3,3.08,-3.08,0.359,0,0,-1.1,1.5
ENSMUSG00000054716,ZFP771,zinc finger protein 771,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.3,1.4,10,0.6,2.35,0.4,3.07,3.07,0.359,0,0,-0.2,1.7
ENSMUSG00000058886,DEAF1,deformed epidermal autoregulatory factor 1 (Drosophila),nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|,"neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|regulation of mammary gland epithelial cell proliferation|regulation of mammary gland epithelial cell proliferation|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system development|",DNA binding|metal ion binding|,10,0.3,1.78,10,0.8,1.91,0.4,3.05,3.05,0.361,0,0,-1.1,1.8
ENSMUSG00000048249,CREBRF,CREB3 regulatory factor,nucleus|cytoplasm|nuclear body|nuclear body|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transport|response to stress|response to unfolded protein|positive regulation of intracellular transport|response to endoplasmic reticulum stress|maternal behavior|maternal behavior|positive regulation of protein catabolic process|positive regulation of protein transport|negative regulation of endoplasmic reticulum unfolded protein response|negative regulation of glucocorticoid mediated signaling pathway|positive regulation of prolactin signaling pathway|",molecular_function|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.3,0.422,10,0.5,3.88,0.4,3.03,3.03,0.362,0,0,-0.8,1.6
ENSMUSG00000023994,NFYA,nuclear transcription factor-Y alpha,nucleus|nucleus|CCAAT-binding factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of stem cell maintenance|positive regulation of stem cell proliferation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|transcription cofactor binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|transcription regulatory region DNA binding|,10,0.4,1.58,10,0.4,1.67,0.4,3.03,3.03,0.362,0,0,-0.9,1.7
ENSMUSG00000039782,CPEB2,cytoplasmic polyadenylation element binding protein 2,nucleus|cytoplasm|cytoplasm|polysome|messenger ribonucleoprotein complex|messenger ribonucleoprotein complex|,regulation of translation|cellular response to insulin stimulus|negative regulation of GTP catabolic process|negative regulation of GTPase activity|cellular response to oxidative stress|cellular response to oxidative stress|negative regulation of translational elongation|cellular response to arsenic-containing substance|cellular response to arsenic-containing substance|cellular response to hypoxia|cellular response to hypoxia|negative regulation of cytoplasmic translational elongation|negative regulation of cytoplasmic translation|negative regulation of cytoplasmic translation|,"nucleotide binding|translation repressor activity, nucleic acid binding|translation repressor activity, nucleic acid binding|nucleic acid binding|RNA binding|GTPase inhibitor activity|protein binding|poly-pyrimidine tract binding|mRNA 3'-UTR AU-rich region binding|ribosome binding|ribosomal large subunit binding|ribosomal small subunit binding|poly(A) RNA binding|",10,0.8,3.09,10,0.2,0.408,0.7,2.97,2.97,0.367,0,0,-0.1,1.8
ENSMUSG00000060261,GTF2I,general transcription factor II I,nucleus|nucleus|cytoplasm|membrane|cell projection|neuronal cell body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|embryo development|transition between slow and fast fiber|negative regulation of angiogenesis|negative regulation of cytosolic calcium ion concentration|",DNA binding|protein binding|mitogen-activated protein kinase binding|,10,-0.4,1.45,10,-0.4,1.73,-0.4,2.97,-2.97,0.367,0,0,-1.6,0.5
ENSMUSG00000022061,NKX3-1,"NK-3 transcription factor, locus 1 (Drosophila)",intracellular|intracellular|intracellular|nucleus|nucleus|,"urogenital system development|positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|activation of cysteine-type endopeptidase activity involved in apoptotic process|multicellular organismal development|salivary gland development|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of gene expression|negative regulation of gene expression|positive regulation of cell death|positive regulation of phosphatidylinositol 3-kinase signaling|androgen receptor signaling pathway|prostate gland development|response to testosterone|internal genitalia morphogenesis|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|steroid hormone mediated signaling pathway|protein kinase B signaling|protein kinase B signaling|negative regulation of insulin-like growth factor receptor signaling pathway|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of mitotic cell cycle|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|branching morphogenesis of an epithelial tube|negative regulation of epithelial cell proliferation|positive regulation of cell division|branching involved in prostate gland morphogenesis|epithelial cell proliferation involved in salivary gland morphogenesis|negative regulation of epithelial cell proliferation involved in prostate gland development|cellular response to steroid hormone stimulus|cellular response to hypoxia|mitotic cell cycle arrest|negative regulation of estrogen receptor binding|positive regulation of androgen secretion|positive regulation of response to DNA damage stimulus|positive regulation of apoptotic signaling pathway|positive regulation of intrinsic apoptotic signaling pathway|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|core promoter binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|androgen receptor activity|protein binding|transcription factor binding|transcription factor binding|transcription factor binding|cysteine-type endopeptidase activator activity involved in apoptotic process|estrogen receptor activity|protein kinase activator activity|estrogen receptor binding|histone deacetylase binding|sequence-specific DNA binding|sequence-specific DNA binding|protein self-association|transcription regulatory region DNA binding|MADS box domain binding|,10,0,0,10,0.5,3.61,0.4,2.97,2.97,0.367,0,0,-0.4,1.5
ENSMUSG00000066224,ARID3C,AT rich interactive domain 3C (BRIGHT-like),intracellular|nucleus|cytoplasm|membrane raft|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|chromatin binding|protein binding|,10,0.9,3.24,10,0.3,0.504,0.5,2.97,2.97,0.367,0,0,-0.4,1.8
ENSMUSG00000061360,PHF5A,PHD finger protein 5A,nucleus|spliceosomal complex|U2 snRNP|U12-type spliceosomal complex|nuclear matrix|nuclear speck|,"mRNA splicing, via spliceosome|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|RNA splicing|positive regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|poly(A) RNA binding|,5,-0.6,3.12,6,-0.2,0.421,-0.6,2.97,-2.97,0.367,0,0,-2,0.9
ENSMUSG00000002833,HDGFRP2,"hepatoma-derived growth factor, related protein 2",nucleus|,"transcription, DNA-templated|biological_process|",DNA binding|chromatin binding|protein binding|,10,0.4,2.16,10,0.5,1.01,0.4,2.95,2.95,0.368,0,0,-0.7,1.7
ENSMUSG00000059119,NAP1L4,nucleosome assembly protein 1-like 4,cellular_component|nucleus|,nucleosome assembly|biological_process|,poly(A) RNA binding|,10,-0.5,2.51,10,0.4,1.95,0.3,2.95,2.95,0.368,0,0,-1.3,1.3
ENSMUSG00000034430,ZXDC,ZXD family zinc finger C,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",nucleic acid binding|sequence-specific DNA binding transcription factor activity|LRR domain binding|metal ion binding|C2H2 zinc finger domain binding|,10,-0.3,1.22,10,-0.6,2.28,-0.3,2.94,-2.94,0.369,0,0,-1.6,0.5
ENSMUSG00000031508,ANKRD10,ankyrin repeat domain 10,cellular_component|,regulation of canonical Wnt signaling pathway|,molecular_function|,10,0,0,10,0.4,3.94,0.4,2.92,2.92,0.37,0,0,-0.5,1.5
ENSMUSG00000002578,IKZF4,IKAROS family zinc finger 4,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|protein binding|protein homodimerization activity|bHLH transcription factor binding|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,-0.6,2.35,10,-0.2,0.941,-0.3,2.9,-2.9,0.372,0,0,-1.7,0.2
ENSMUSG00000011837,SNAPC2,"small nuclear RNA activating complex, polypeptide 2",nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,7,0.8,5.42,8,-0.6,0.525,0.7,2.89,2.89,0.373,0,0,-0.8,2
ENSMUSG00000045336,HSFY2,"heat shock transcription factor, Y linked 2",cellular_component|nucleus|,response to stress|biological_process|,molecular_function|DNA binding|,10,-0.6,3.86,10,0.2,0.346,-0.6,2.89,-2.89,0.373,0,0,-1.8,0.5
ENSMUSG00000017830,DHX58,DEXH (Asp-Glu-X-His) box polypeptide 58,cytoplasm|,immune system process|response to virus|negative regulation of type I interferon production|negative regulation of type I interferon production|positive regulation of type I interferon production|negative regulation of MDA-5 signaling pathway|negative regulation of RIG-I signaling pathway|negative regulation of RIG-I signaling pathway|innate immune response|regulation of innate immune response|negative regulation of innate immune response|negative regulation of innate immune response|defense response to virus|positive regulation of MDA-5 signaling pathway|positive regulation of RIG-I signaling pathway|,"nucleotide binding|DNA binding|RNA binding|double-stranded RNA binding|double-stranded RNA binding|single-stranded RNA binding|helicase activity|ATP binding|zinc ion binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|metal ion binding|",10,-0.5,2.71,10,-0.3,0.947,-0.4,2.89,-2.89,0.373,0,0,-1.6,0.9
ENSMUSG00000004263,ATN1,atrophin 1,nucleus|nucleus|nucleus|cytoplasm|nuclear matrix|cell junction|cell leading edge|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|toxin metabolic process|cell migration|maintenance of cell polarity|neuron apoptotic process|regulation of RNA biosynthetic process|",transcription corepressor activity|transcription corepressor activity|protein binding|JUN kinase binding|protein domain specific binding|toxin receptor binding|,9,0.4,1.84,9,0.3,1.27,0.3,2.89,2.89,0.373,0,0,-0.9,1.5
ENSMUSG00000057173,RFX8,regulatory factor X 8,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|,10,-0.6,3.73,10,-0.2,0.797,-0.3,2.87,-2.87,0.374,0,0,-1.8,0.3
ENSMUSG00000063889,CREM,cAMP responsive element modulator,nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|glycosphingolipid metabolic process|spermatogenesis|spermatogenesis|circadian regulation of gene expression|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|response to cAMP|",core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.5,2.24,10,0.3,1.1,0.4,2.86,2.86,0.375,0,0,-0.4,1.7
ENSMUSG00000003039,FAM32A,"family with sequence similarity 32, member A",nucleus|mitochondrion|intracellular membrane-bounded organelle|,apoptotic process|cell cycle|biological_process|,poly(A) RNA binding|,10,0.4,0.55,9,0.6,2.65,0.5,2.83,2.83,0.378,0,0,-0.5,1.6
ENSMUSG00000026816,GTF3C5,"general transcription factor IIIC, polypeptide 5",transcription factor TFIIIC complex|nucleus|,"transcription, DNA-templated|skeletal muscle cell differentiation|",molecular_function|DNA binding|,8,1.7,4.95,10,-0.5,3.71,-0.4,2.81,-2.81,0.379,0,0,-1.7,2.7
ENSMUSG00000004096,CWC15,CWC15 homolog (S. cerevisiae),nucleus|spliceosomal complex|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|mRNA processing|biological_process|RNA splicing|",molecular_function|,10,-0.4,2.72,10,0.2,0.841,-0.4,2.81,-2.81,0.379,0,0,-1.5,0.7
ENSMUSG00000031626,SORBS2,sorbin and SH3 domain containing 2,cytoplasm|cytoskeleton|plasma membrane|postsynaptic density|cell junction|dendrite|neuronal cell body|,actin filament organization|cell adhesion|cell migration|,protein domain specific binding|poly(A) RNA binding|metal ion binding|,9,1,3.56,9,0.1,0.000421,0.3,2.79,2.79,0.381,0,0,-0.4,2
ENSMUSG00000028546,ELAVL4,"ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)",None,None,nucleotide binding|nucleic acid binding|RNA binding|AU-rich element binding|,10,0.4,0.706,10,0.7,2.35,0.7,2.78,2.78,0.382,0,0,-0.7,2
ENSMUSG00000050996,CETN1,centrin 1,spindle pole|cytoplasm|centrosome|centrosome|centriole|cytoskeleton|photoreceptor connecting cilium|,cell cycle|mitotic nuclear division|cellular response to heat|cell division|,nucleic acid binding|calcium ion binding|ATP binding|microtubule binding|ATP-dependent helicase activity|G-protein beta/gamma-subunit complex binding|heterotrimeric G-protein binding|metal ion binding|,10,0,0,10,-0.5,3.63,-0.3,2.76,-2.76,0.383,0,0,-1.6,0.6
ENSMUSG00000067367,LYAR,Ly1 antibody reactive clone,nucleus|nucleolus|nucleolus|,biological_process|,poly(A) RNA binding|metal ion binding|,10,-0.1,0.0564,10,1.5,6.04,1.5,2.75,2.75,0.384,0,0,-0.1,3
ENSMUSG00000049800,SERTAD2,SERTA domain containing 2,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cell growth|positive regulation of transcription, DNA-templated|",transcription coactivator activity|protein binding|,10,-0.1,0.152,10,-1.2,3.63,-0.3,2.74,-2.74,0.385,0,0,-2,0.2
ENSMUSG00000044155,NAA38,"N(alpha)-acetyltransferase 38, NatC auxiliary subunit",nucleus|cytoplasm|polysome|NatC complex|,negative regulation of apoptotic process|,molecular_function|,9,-0.1,0.00288,10,1,4.64,0.9,2.73,2.73,0.386,0,0,-0.3,2
ENSMUSG00000028060,2810403A07RIK,RIKEN cDNA 2810403A07 gene,cellular_component|,biological_process|,RNA binding|,9,-0.4,0.974,9,0.8,3.92,0.5,2.73,2.73,0.386,0,0,-0.6,2
ENSMUSG00000053470,KDM3A,lysine (K)-specific demethylase 3A,nucleus|nucleus|cytoplasm|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|spermatid nucleus elongation|hormone-mediated signaling pathway|chromatin modification|cell differentiation|androgen receptor signaling pathway|histone H3-K9 demethylation|histone H3-K9 dimethylation|histone H3-K9 dimethylation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|formaldehyde biosynthetic process|negative regulation of histone H3-K9 methylation|oxidation-reduction process|","sulfonate dioxygenase activity|transcription regulatory region sequence-specific DNA binding|core promoter binding|sequence-specific DNA binding transcription factor activity|iron ion binding|protein binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|androgen receptor binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.3,1.03,10,-0.5,1.95,-0.4,2.72,-2.72,0.387,0,0,-1.4,1.6
ENSMUSG00000020798,SPNS3,spinster homolog 3,cellular_component|membrane|integral component of membrane|,transport|lipid transport|biological_process|transmembrane transport|,molecular_function|,10,0.1,0.135,10,-1.2,4.35,-0.3,2.72,-2.72,0.387,0,0,-2,0.2
ENSMUSG00000029826,ZC3HAV1,"zinc finger CCCH type, antiviral 1",nucleus|cytoplasm|Golgi apparatus|plasma membrane|,immune system process|response to virus|positive regulation of type I interferon production|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|positive regulation of ATPase activity|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of viral genome replication|innate immune response|regulation of defense response to virus by host|defense response to virus|positive regulation of mRNA catabolic process|cellular response to exogenous dsRNA|positive regulation of RIG-I signaling pathway|positive regulation of RIG-I signaling pathway|,RNA binding|NAD+ ADP-ribosyltransferase activity|DEAD/H-box RNA helicase binding|poly(A) RNA binding|metal ion binding|,10,-0.5,2.35,10,-0.3,0.716,-0.4,2.71,-2.71,0.387,0,0,-1.6,0.4
ENSMUSG00000031099,SMARCA1,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1",nuclear chromatin|nucleus|NURF complex|CERF complex|,"DNA strand renaturation|ATP catabolic process|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|brain development|brain development|chromatin modification|neuron differentiation|ATP-dependent chromatin remodeling|positive regulation of transcription, DNA-templated|regulation of neural precursor cell proliferation|regulation of neural precursor cell proliferation|","nucleotide binding|nucleic acid binding|DNA binding|chromatin binding|helicase activity|ATP binding|DNA-dependent ATPase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|nucleosome binding|annealing helicase activity|nucleosome-dependent ATPase activity|",10,-0.5,2.51,10,0.2,1.12,-0.5,2.68,-2.68,0.39,0,0,-1.6,0.8
ENSMUSG00000020075,DDX21,DEAD (Asp-Glu-Ala-Asp) box polypeptide 21,nucleus|nucleus|nucleolus|nucleolus|membrane|,osteoblast differentiation|response to virus|response to exogenous dsRNA|,nucleotide binding|nucleic acid binding|RNA binding|RNA helicase activity|double-stranded RNA binding|helicase activity|protein binding|ATP binding|hydrolase activity|poly(A) RNA binding|,10,-0.8,4.41,10,1,1.99,-0.4,2.66,-2.66,0.392,0,0,-2,1.2
ENSMUSG00000039552,RSPH4A,radial spoke head 4 homolog A (Chlamydomonas),nucleus|cytoplasm|cytoskeleton|cilium|cell projection|,cilium movement|axoneme assembly|,molecular_function|,10,1,4.32,10,-0.2,0.393,0.2,2.65,2.65,0.393,0,0,-0.7,2
ENSMUSG00000040632,NRL,neural retina leucine zipper gene,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|regulation of rhodopsin gene expression|positive regulation of rhodopsin gene expression|positive regulation of rhodopsin gene expression|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|retinal rod cell development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|leucine zipper domain binding|sequence-specific DNA binding|,10,-0.2,0.531,10,-0.4,2.59,-0.3,2.61,-2.61,0.396,0,0,-1.5,0.7
ENSMUSG00000074971,FIBIN,fin bud initiation factor homolog (zebrafish),extracellular region|endoplasmic reticulum|Golgi apparatus|,biological_process|,molecular_function|,10,-0.2,0.29,10,-0.4,2.81,-0.3,2.6,-2.6,0.397,0,0,-1.5,0.4
ENSMUSG00000034732,PABPC5,"poly(A) binding protein, cytoplasmic 5",cellular_component|,biological_process|,molecular_function|,10,-0.3,1.54,10,-0.2,1.29,-0.3,2.59,-2.59,0.398,0,0,-1.3,1.4
ENSMUSG00000024948,MAP4K2,mitogen-activated protein kinase kinase kinase kinase 2,intracellular|cytoplasm|Golgi apparatus|plasma membrane|membrane|,MAPK cascade|activation of MAPKKK activity|immune system process|protein phosphorylation|protein phosphorylation|vesicle targeting|response to stress|activation of JUN kinase activity|phosphorylation|intracellular signal transduction|innate immune response|positive regulation of JNK cascade|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase kinase binding|",10,0.9,3.26,10,-0.2,0.294,0.4,2.57,2.57,0.4,0,0,-0.4,2
ENSMUSG00000046792,ZFP787,zinc finger protein 787,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.3,2.93,10,0.1,0.324,0.2,2.57,2.57,0.4,0,0,-0.4,1.6
ENSMUSG00000031134,RBMX,"RNA binding motif protein, X chromosome",extracellular space|nucleus|spliceosomal complex|nuclear euchromatin|membrane|ribonucleoprotein complex|supraspliceosomal complex|extracellular vesicular exosome|catalytic step 2 spliceosome|,"regulation of alternative mRNA splicing, via spliceosome|osteoblast differentiation|transcription, DNA-templated|transcription from RNA polymerase II promoter|mRNA splice site selection|mRNA processing|membrane protein ectodomain proteolysis|RNA splicing|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|cellular response to interleukin-1|",nucleotide binding|core promoter binding|nucleic acid binding|chromatin binding|RNA binding|single-stranded RNA binding|mRNA binding|poly(A) RNA binding|,10,1.1,5.62,10,-0.2,0.873,1.1,2.56,2.56,0.401,0,0,-0.4,2
ENSMUSG00000043219,HOXA6,homeobox A6,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|embryonic skeletal system morphogenesis|embryonic skeletal system development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.1,0.167,10,-0.3,2.87,-0.3,2.56,-2.56,0.401,0,0,-2,0.6
ENSMUSG00000040167,IKZF5,IKAROS family zinc finger 5,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.3,0.685,10,0.4,2.32,0.4,2.56,2.56,0.401,0,0,-0.6,1.4
ENSMUSG00000037206,ISLR,immunoglobulin superfamily containing leucine-rich repeat,extracellular region|extracellular vesicular exosome|,None,None,10,1,4.09,10,-0.2,0.449,0.2,2.53,2.53,0.403,0,0,-0.3,2
ENSMUSG00000010175,PROX1,prospero homeobox 1,nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cell fate determination|positive regulation of endothelial cell proliferation|lymph vessel development|lymphangiogenesis|lens morphogenesis in camera-type eye|hepatocyte cell migration|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|regulation of gene expression|regulation of gene expression|positive regulation of endothelial cell migration|dentate gyrus development|cerebellar granule cell differentiation|skeletal muscle thin filament assembly|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of viral genome replication|endothelial cell differentiation|positive regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of cell cycle|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|inner ear development|venous blood vessel morphogenesis|ventricular cardiac myofibril assembly|atrial cardiac muscle tissue morphogenesis|ventricular cardiac muscle tissue morphogenesis|endocardium formation|positive regulation of sarcomere organization|ventricular septum morphogenesis|aorta smooth muscle tissue morphogenesis|positive regulation of heart growth|lymphatic endothelial cell differentiation|lymphatic endothelial cell differentiation|regulation of transcription involved in lymphatic endothelial cell fate commitment|branching involved in pancreas morphogenesis|lens fiber cell morphogenesis|negative regulation of bile acid biosynthetic process|hepatocyte proliferation|acinar cell differentiation|neuronal stem cell maintenance|positive regulation of cell cycle checkpoint|positive regulation of neural precursor cell proliferation|positive regulation of forebrain neuron differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription corepressor activity|ligand-dependent nuclear receptor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|DBD domain binding|LBD domain binding|,10,0.4,2.05,10,0.3,0.732,0.3,2.52,2.52,0.404,0,0,-0.6,1.8
ENSMUSG00000038253,HOXA5,homeobox A5,nucleus|nucleus|,"skeletal system development|morphogenesis of an epithelium|respiratory system process|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|respiratory gaseous exchange|anterior/posterior pattern specification|anterior/posterior pattern specification|positive regulation of receptor biosynthetic process|cell migration|negative regulation of angiogenesis|lung development|thyroid gland development|regulation of mammary gland epithelial cell proliferation|multicellular organism growth|positive regulation of apoptotic process|positive regulation of myeloid cell differentiation|negative regulation of erythrocyte differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|lung alveolus development|embryonic skeletal system morphogenesis|embryonic skeletal system development|bronchiole development|trachea morphogenesis|epithelial tube branching involved in lung morphogenesis|lung goblet cell differentiation|lobar bronchus epithelium development|lung-associated mesenchyme development|trachea cartilage morphogenesis|cartilage morphogenesis|intestinal epithelial cell maturation|mesenchymal-epithelial cell signaling|mammary gland epithelial cell differentiation|mammary gland alveolus development|cell-cell signaling involved in mammary gland development|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,-0.6,3.05,10,-0.2,0.45,-0.5,2.51,-2.51,0.405,0,0,-2,2.5
ENSMUSG00000051159,CITED1,Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1,nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytosol|,"embryonic axis specification|vasculogenesis|placenta development|negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|nucleocytoplasmic transport|apoptotic process|transforming growth factor beta receptor signaling pathway|multicellular organismal development|positive regulation of gene expression|cell differentiation|melanocyte differentiation|melanocyte differentiation|response to lipopolysaccharide|response to insulin|response to cytokine|response to interferon-gamma|melanin biosynthetic process|pigmentation|pigmentation|pigmentation|negative regulation of neuron apoptotic process|response to estrogen|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|response to cAMP|SMAD protein signal transduction|labyrinthine layer development|spongiotrophoblast layer development|response to interleukin-1|response to interleukin-2|response to interleukin-4|response to interleukin-6|response to interleukin-9|response to interleukin-11|response to parathyroid hormone|response to transforming growth factor beta|",chromatin binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|protein C-terminus binding|protein homodimerization activity|transcription regulatory region DNA binding|LBD domain binding|co-SMAD binding|,10,0.2,1.21,10,0.3,1.47,0.3,2.49,2.49,0.407,0,0,-0.4,1.6
ENSMUSG00000037007,ZFP113,zinc finger protein 113,None,biological_process|,identical protein binding|metal ion binding|,10,1.1,5.01,10,-0.6,1.58,0.2,2.48,2.48,0.408,0,0,-0.6,2
ENSMUSG00000009739,POU6F1,"POU domain, class 6, transcription factor 1",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,-0.3,3.38,-0.3,2.47,-2.47,0.408,0,0,-1.5,0.6
ENSMUSG00000029033,ACAP3,"ArfGAP with coiled-coil, ankyrin repeat and PH domains 3",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.4,1.22,10,0.4,1.42,0.4,2.46,2.46,0.409,0,0,-0.6,1.8
ENSMUSG00000062518,ZFP534,zinc finger protein 534,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,3,-0.8,3.88,3,0.2,0.364,-0.7,2.45,-2.45,0.41,0,0,-2,1
ENSMUSG00000057894,ZFP329,zinc finger protein 329,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.2,0.923,10,0.5,2.63,0.3,2.42,2.42,0.413,0,0,-0.3,1.8
ENSMUSG00000029439,SFSWAP,"splicing factor, suppressor of white-apricot homolog (Drosophila)",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|RNA processing|mRNA processing|RNA splicing|negative regulation of mRNA splicing, via spliceosome|",RNA binding|,10,0.6,0.735,10,1,2.1,0.7,2.42,2.42,0.413,0,0,-0.4,2
ENSMUSG00000058046,4933430I17RIK,RIKEN cDNA 4933430I17 gene,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.81,10,-0.5,2.03,-0.4,2.38,-2.38,0.417,0,0,-1.5,0.7
ENSMUSG00000031590,FRG1,FSHD region gene 1,nucleus|spliceosomal complex|catalytic step 2 spliceosome|,rRNA processing|mRNA processing|RNA splicing|ribosome biogenesis|,poly(A) RNA binding|,10,0.2,0.369,10,0.3,2.2,0.3,2.36,2.36,0.419,0,0,-0.5,1.5
ENSMUSG00000075304,SP5,trans-acting transcription factor 5,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|post-anal tail morphogenesis|bone morphogenesis|",nucleic acid binding|DNA binding|sequence-specific DNA binding|metal ion binding|,10,-0.3,0.901,10,-0.3,1.6,-0.3,2.33,-2.33,0.422,0,0,-1.7,0.5
ENSMUSG00000022761,LZTR1,"leucine-zipper-like transcriptional regulator, 1",cellular_component|,biological_process|,molecular_function|,10,0.4,1.14,10,0.4,1.37,0.4,2.33,2.33,0.422,0,0,-0.5,1.6
ENSMUSG00000028318,POLR1E,polymerase (RNA) I polypeptide E,nucleus|nucleolus|DNA-directed RNA polymerase I complex|DNA-directed RNA polymerase I complex|,"RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript|transcription, DNA-templated|",RNA polymerase I activity|RNA polymerase I transcription factor binding|DNA binding|DNA-directed RNA polymerase activity|protein binding|,10,-0.6,1.12,9,-0.4,1.55,-0.5,2.33,-2.33,0.422,0,0,-1.8,0.8
ENSMUSG00000034057,MYRFL,myelin regulatory factor-like,cellular_component|membrane|integral component of membrane|,"regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.2,0.614,10,-0.5,2.27,-0.3,2.33,-2.33,0.422,0,0,-1.6,0.4
ENSMUSG00000045098,SUV420H1,suppressor of variegation 4-20 homolog 1 (Drosophila),"condensed nuclear chromosome, centromeric region|nucleus|chromosome|","transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone methylation|peptidyl-lysine methylation|methylation|histone H4-K20 methylation|histone H4-K20 trimethylation|histone lysine methylation|",methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H4-K20 specific)|,10,-0.2,0.627,10,-0.7,2.95,-0.4,2.3,-2.3,0.425,0,0,-1.8,0.3
ENSMUSG00000050272,DSCAM,Down syndrome cell adhesion molecule,plasma membrane|membrane|integral component of membrane|axon|growth cone|,cell adhesion|negative regulation of cell adhesion|nervous system development|locomotory behavior|positive regulation of phosphorylation|dendrite morphogenesis|positive regulation of axon extension involved in axon guidance|positive regulation of axon extension involved in axon guidance|post-embryonic retina morphogenesis in camera-type eye|dendrite self-avoidance|,protein binding|,10,-0.6,2.74,10,-0.2,0.569,-0.3,2.28,-2.28,0.427,0,0,-1.8,0.3
ENSMUSG00000070031,SP140,Sp140 nuclear body protein,None,biological_process|,molecular_function|metal ion binding|,8,-0.5,0.544,8,1.4,4.97,1.3,2.2,2.2,0.435,0,0,-0.8,2
ENSMUSG00000032526,DEB1,differentially expressed in B16F10 1,cellular_component|,biological_process|,molecular_function|,9,2,1.93,7,-0.3,1.56,-0.3,2.2,-2.2,0.435,0,0,-2,3.2
ENSMUSG00000028568,BTF3L4,basic transcription factor 3-like 4,cellular_component|,biological_process|,molecular_function|,10,0.5,1.18,10,0.3,1.66,0.3,2.18,2.18,0.437,0,0,-0.7,1.6
ENSMUSG00000021113,SNAPC1,"small nuclear RNA activating complex, polypeptide 1",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|,8,-0.6,1.05,9,-0.3,1.78,-0.3,2.18,-2.18,0.437,0,0,-1.8,1.1
ENSMUSG00000061024,RRS1,RRS1 ribosome biogenesis regulator homolog (S. cerevisiae),condensed nuclear chromosome|nucleus|nucleolus|nucleolus|endoplasmic reticulum|,hematopoietic progenitor cell differentiation|mitotic metaphase plate congression|ribosome biogenesis|,protein binding|poly(A) RNA binding|,9,-0.4,1.06,9,1.3,2.24,-0.5,2.17,-2.17,0.438,0,0,-1.5,1.9
ENSMUSG00000011267,ZFP296,zinc finger protein 296,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,3.1,-0.3,2.14,-2.14,0.441,0,0,-1.6,0.5
ENSMUSG00000041762,GPR155,G protein-coupled receptor 155,extracellular vesicular exosome|,cognition|,molecular_function|,10,-0.8,4.85,10,0.2,0.384,-0.7,2.13,-2.13,0.443,0,0,-2,0.8
ENSMUSG00000026638,IRF6,interferon regulatory factor 6,nucleus|cytoplasm|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle arrest|negative regulation of cell proliferation|negative regulation of cell proliferation|cell differentiation|keratinocyte differentiation|skin development|skin development|keratinocyte proliferation|keratinocyte proliferation|positive regulation of transcription, DNA-templated|cell development|",regulatory region DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|,10,0.1,0.0853,10,-1,4.82,-0.9,2.13,-2.13,0.443,0,0,-2,0.3
ENSMUSG00000033356,PUS7L,pseudouridylate synthase 7 homolog (S. cerevisiae)-like,cellular_component|,pseudouridine synthesis|tRNA processing|RNA modification|,RNA binding|pseudouridine synthase activity|isomerase activity|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|baruol synthase activity|,10,0.4,1.26,10,0.3,1.14,0.3,2.13,2.13,0.443,0,0,-0.7,1.6
ENSMUSG00000095909,GM10324,predicted gene 10324,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.5,2.69,10,0,0,-0.4,2.11,-2.11,0.445,0,0,-1.6,1.3
ENSMUSG00000026468,LHX4,LIM homeobox protein 4,intracellular|nucleus|,"placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|motor neuron axon guidance|organ morphogenesis|medial motor column neuron differentiation|negative regulation of apoptotic process|",DNA binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.2,0.383,10,-0.4,2.35,-0.4,2.11,-2.11,0.445,0,0,-1.6,0.6
ENSMUSG00000024276,ZFP397,zinc finger protein 397,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|metal ion binding|,10,0.3,1.65,10,0.5,0.636,0.4,2.1,2.1,0.446,0,0,-0.4,1.8
ENSMUSG00000049755,ZFP672,zinc finger protein 672,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.6,2.1,10,0.4,1.61,0.4,2.09,2.09,0.447,0,0,-1.6,1.2
ENSMUSG00000062175,TGIF2,TGFB-induced factor homeobox 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of gastrulation|nodal signaling pathway|positive regulation of neuron differentiation|retina development in camera-type eye|",DNA binding|,10,0.7,3.05,10,-0.4,3.25,0.5,2.09,2.09,0.447,0,0,-0.9,1.7
ENSMUSG00000062861,ZFP28,zinc finger protein 28,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.3,1.6,10,-0.2,0.661,-0.3,2.08,-2.08,0.448,0,0,-1.5,1.1
ENSMUSG00000034271,JDP2,Jun dimerization protein 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of histone deacetylation|negative regulation of fat cell differentiation|",DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|protein heterodimerization activity|,10,0.2,1.53,10,0.3,0.717,0.2,2.07,2.07,0.45,0,0,-0.8,1.5
ENSMUSG00000046058,EID2,EP300 interacting inhibitor of differentiation 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transforming growth factor beta receptor complex assembly|SMAD protein complex assembly|multicellular organismal development|muscle organ development|regulation of transforming growth factor beta receptor signaling pathway|cell differentiation|negative regulation of transforming growth factor beta receptor signaling pathway|regulation of cell proliferation|negative regulation of transcription, DNA-templated|",SMAD binding|,10,0.3,0.784,10,0.4,1.73,0.3,2.07,2.07,0.45,0,0,-0.7,1.7
ENSMUSG00000024498,TCERG1,transcription elongation regulator 1 (CA150),nucleus|nuclear matrix|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II repressing transcription factor binding|RNA polymerase II transcription corepressor activity|sequence-specific DNA binding transcription factor activity|poly(A) RNA binding|proline-rich region binding|,9,0.5,3.64,9,-0.4,0.193,0.4,2.07,2.07,0.45,0,0,-1.1,1.6
ENSMUSG00000055932,FTO,fat mass and obesity associated,nucleus|nuclear speck|,temperature homeostasis|DNA repair|DNA dealkylation involved in DNA repair|DNA dealkylation involved in DNA repair|cellular response to DNA damage stimulus|regulation of lipid storage|oxidative single-stranded DNA demethylation|oxidative single-stranded DNA demethylation|oxidative single-stranded RNA demethylation|oxidative single-stranded RNA demethylation|regulation of multicellular organism growth|RNA repair|RNA repair|regulation of respiratory system process|oxidation-reduction process|adipose tissue development|regulation of white fat cell proliferation|oxidative demethylation|oxidative demethylation|DNA demethylation|DNA demethylation|,"sulfonate dioxygenase activity|ferrous iron binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|oxidative RNA demethylase activity|oxidative RNA demethylase activity|oxidative DNA demethylase activity|oxidative DNA demethylase activity|DNA-N1-methyladenine dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0,0,10,0.5,3.29,0.4,2.04,2.04,0.453,0,0,-0.5,1.7
ENSMUSG00000036036,ZFP57,zinc finger protein 57,intracellular|nucleus|nuclear heterochromatin|,"negative regulation of transcription from RNA polymerase II promoter|regulation of gene expression by genetic imprinting|regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|DNA methylation involved in embryo development|DNA methylation involved in embryo development|",nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,0,0,10,-0.5,4.12,-0.5,2.03,-2.03,0.454,0,0,-1.8,0.4
ENSMUSG00000020420,ZFP607,zinc finger proten 607,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.268,10,-0.6,2.89,-0.5,2.01,-2.01,0.456,0,0,-1.8,0.4
ENSMUSG00000026946,NMI,N-myc (and STAT) interactor,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.2,0.429,10,0.3,1.97,0.3,2.01,2.01,0.456,0,0,-1.2,1.5
ENSMUSG00000038279,NOP2,NOP2 nucleolar protein,nucleus|nucleolus|,rRNA processing|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0.4,3,0.4,2.01,2.01,0.456,0,0,-0.7,1.7
ENSMUSG00000044709,GEMIN7,gem (nuclear organelle) associated protein 7,nucleus|nucleoplasm|cytoplasm|cytosol|nuclear body|SMN complex|SMN-Sm protein complex|,spliceosomal snRNP assembly|mRNA processing|RNA splicing|,protein binding|,10,-0.6,1.48,9,-0.3,0.992,-0.3,2,-2,0.458,0,0,-1.5,1.5
ENSMUSG00000014686,CEACAM16,carcinoembryonic antigen-related cell adhesion molecule 16,extracellular region|stereocilium bundle tip|,sensory perception of sound|,protein binding|,9,1,4.22,9,0,0,0.2,1.99,1.99,0.459,0,0,-0.1,2
ENSMUSG00000026571,DCAF6,DDB1 and CUL4 associated factor 6,nucleus|Cul4-RING E3 ubiquitin ligase complex|,positive regulation of transcription from RNA polymerase II promoter|,ligand-dependent nuclear receptor transcription coactivator activity|,10,0,0,10,-1.2,4.95,-1.1,1.96,-1.96,0.462,0,0,-2,0.1
ENSMUSG00000043753,DMRTA1,doublesex and mab-3 related transcription factor like family A1,cellular_component|nucleus|,"ovarian follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|male mating behavior|",DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|,10,-0.5,0.254,10,0.6,2.87,0.4,1.92,1.92,0.467,0,0,-1.5,1.5
ENSMUSG00000035215,LSM7,"LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)",cytoplasm|,mRNA catabolic process|,protein binding|protein heterodimerization activity|,7,0.4,1.2,6,0.3,0.881,0.3,1.92,1.92,0.467,0,0,-0.7,2
ENSMUSG00000032717,MDFI,MyoD family inhibitor,nucleus|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|activation of JUN kinase activity|multicellular organismal development|dorsal/ventral axis specification|regulation of Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|negative regulation of DNA binding|embryonic skeletal system morphogenesis|trophoblast giant cell differentiation|,protein binding|transcription factor binding|,10,0.4,1.33,10,0.3,0.848,0.3,1.9,1.9,0.469,0,0,-1.4,1.3
ENSMUSG00000037017,ZSCAN21,zinc finger and SCAN domain containing 21,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|cell differentiation|positive regulation of transcription, DNA-templated|oogenesis|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.386,10,0.4,2.83,0.3,1.88,1.88,0.471,0,0,-1,1.5
ENSMUSG00000049641,VGLL2,vestigial like 2 homolog (Drosophila),nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|skeletal muscle tissue development|positive regulation of transcription from RNA polymerase II promoter|",transcription coactivator activity|protein binding|,10,0,0,10,0.3,2.6,0.3,1.88,1.88,0.471,0,0,-1,1.4
ENSMUSG00000042414,PRDM14,PR domain containing 14,nucleus|,"cell morphogenesis|cell fate specification|inner cell mass cell fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|germ cell development|fertilization|regulation of gene expression|germ-line stem cell maintenance|methylation|histone H3-R26 methylation|regulation of gene expression, epigenetic|negative regulation of fibroblast growth factor receptor signaling pathway|regulation of DNA methylation|homeostasis of number of cells within a tissue|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|DNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.4,0.695,10,-1.2,3.88,-0.8,1.87,-1.87,0.473,0,0,-2,0.7
ENSMUSG00000001444,TBX21,T-box 21,nucleus|neuronal cell body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|T cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of isotype switching to IgG isotypes|regulation of immune response|cellular response to organic substance|lymphocyte migration|lymphocyte migration|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription regulatory region DNA binding|,10,0.4,0.931,10,0.3,1.14,0.3,1.86,1.86,0.474,0,0,-0.9,1.6
ENSMUSG00000020335,ZFP354B,zinc finger protein 354B,intracellular|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.5,3.4,10,-0.3,1.25,0.4,1.86,1.86,0.474,0,0,-0.9,1.5
ENSMUSG00000025229,PITX3,paired-like homeodomain transcription factor 3,nucleus|,"lens development in camera-type eye|lens morphogenesis in camera-type eye|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|locomotory behavior|regulation of gene expression|regulation of gene expression|regulation of gene expression|midbrain development|positive regulation of transcription, DNA-templated|neuron development|lens fiber cell differentiation|dopaminergic neuron differentiation|dopaminergic neuron differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|,10,0.8,2.31,10,0.2,0.7,0.5,1.86,1.86,0.474,0,0,-1,1.8
ENSMUSG00000051184,ZFP524,zinc finger protein 524,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.3,2.43,10,-0.1,0.022,-0.3,1.85,-1.85,0.476,0,0,-1.7,0.6
ENSMUSG00000008658,RBFOX1,"RNA binding protein, fox-1 homolog (C. elegans) 1",nucleus|cytoplasm|cytoplasm|trans-Golgi network|,mRNA processing|RNA splicing|regulation of RNA splicing|neuromuscular process controlling balance|,nucleotide binding|nucleic acid binding|RNA binding|protein C-terminus binding|,10,1,2.59,10,0.2,0.492,0.2,1.84,1.84,0.477,0,0,-0.3,2
ENSMUSG00000037617,SPAG1,sperm associated antigen 1,nucleus|cytoplasm|microtubule cytoskeleton|,single fertilization|,nucleotide binding|GTP binding|hydrolase activity|,10,-0.1,0.198,10,-0.3,2.31,-0.2,1.83,-1.83,0.478,0,0,-1.6,0.8
ENSMUSG00000005470,ASF1B,anti-silencing function 1B histone chaperone,chromatin|nuclear chromatin|nucleus|protein complex|,"chromatin assembly or disassembly|nucleosome assembly|DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|",histone binding|,9,0.6,2.31,9,-0.3,1.18,0.5,1.82,1.82,0.479,0,0,-1.2,1.6
ENSMUSG00000002881,NAB1,Ngfi-A binding protein 1,nucleus|,"endochondral ossification|transcription, DNA-templated|regulation of transcription, DNA-templated|Schwann cell differentiation|myelination|regulation of epidermis development|negative regulation of transcription, DNA-templated|",transcription factor binding|,10,0.4,2.47,10,0.1,0.0819,0.3,1.81,1.81,0.481,0,0,-0.5,1.8
ENSMUSG00000000731,AIRE,autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy),intracellular|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|humoral immune response|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|chromatin binding|zinc ion binding|histone binding|identical protein binding|transcription regulatory region DNA binding|translation regulator activity|metal ion binding|,10,-0.6,1.35,10,0.2,0.91,-0.7,1.81,-1.81,0.481,0,0,-1.9,0.7
ENSMUSG00000052707,TNRC6A,trinucleotide repeat containing 6a,cytoplasmic mRNA processing body|cytoplasmic mRNA processing body|cytoplasm|micro-ribonucleoprotein complex|perinuclear region of cytoplasm|,regulation of translation|cellular response to starvation|gene silencing by RNA|maintenance of protein location in cell|negative regulation of translation involved in gene silencing by miRNA|,nucleotide binding|nucleic acid binding|RNA binding|protein complex scaffold|poly(A) RNA binding|,10,-0.3,1.24,10,0.3,1.23,-0.3,1.8,-1.8,0.482,0,0,-1.4,1.1
ENSMUSG00000045591,OLIG3,oligodendrocyte transcription factor 3,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|regulation of gene expression|spinal cord motor neuron cell fate specification|spinal cord motor neuron differentiation|spinal cord motor neuron differentiation|spinal cord motor neuron migration|",RNA polymerase II transcription corepressor activity|DNA binding|protein dimerization activity|,10,-0.5,2.1,10,-0.2,0.186,-0.4,1.79,-1.79,0.483,0,0,-1.7,0.6
ENSMUSG00000027359,SLC27A2,"solute carrier family 27 (fatty acid transporter), member 2",mitochondrion|peroxisome|peroxisome|peroxisome|peroxisome|peroxisomal membrane|integral component of peroxisomal membrane|integral component of peroxisomal membrane|endoplasmic reticulum|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum lumen|endoplasmic reticulum membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|intracellular membrane-bounded organelle|extracellular vesicular exosome|,very long-chain fatty acid metabolic process|fatty acid alpha-oxidation|long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|long-chain fatty acid metabolic process|lipid metabolic process|fatty acid metabolic process|fatty acid beta-oxidation|bile acid biosynthetic process|metabolic process|fatty acid transport|very long-chain fatty acid catabolic process|long-chain fatty acid import|methyl-branched fatty acid metabolic process|,"nucleotide binding|catalytic activity|acyl-CoA ligase activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|long-chain fatty acid-CoA ligase activity|succinate-CoA ligase activity|receptor binding|ATP binding|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity|fatty acid transporter activity|fatty acid ligase activity|ligase activity|3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity|2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity|benzoyl acetate-CoA ligase activity|2,4-dichlorobenzoate-CoA ligase activity|enzyme binding|very long-chain fatty acid-CoA ligase activity|very long-chain fatty acid-CoA ligase activity|very long-chain fatty acid-CoA ligase activity|pivalate-CoA ligase activity|cyclopropanecarboxylate-CoA ligase activity|adipate-CoA ligase activity|citronellyl-CoA ligase activity|mentha-1,3-dione-CoA ligase activity|thiophene-2-carboxylate-CoA ligase activity|2,4,4-trimethylpentanoate-CoA ligase activity|cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity|branched-chain acyl-CoA synthetase (ADP-forming) activity|aryl-CoA synthetase (ADP-forming) activity|3-hydroxypropionyl-CoA synthetase activity|phytanate-CoA ligase activity|perillic acid:CoA ligase (ADP-forming) activity|perillic acid:CoA ligase (AMP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity|(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity|pristanate-CoA ligase activity|malonyl-CoA synthetase activity|",10,0.7,1.15,10,-0.3,2.93,-0.2,1.76,-1.76,0.487,0,0,-1,1.7
ENSMUSG00000035946,GSX2,GS homeobox 2,nucleus|,"regulation of respiratory gaseous exchange by neurological system process|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|pattern specification process|pattern specification process|central nervous system development|brain development|spinal cord association neuron differentiation|subpallium development|hindbrain morphogenesis|forebrain dorsal/ventral pattern formation|olfactory bulb interneuron differentiation|telencephalon regionalization|regulation of cell migration|positive regulation of Notch signaling pathway|neuron fate commitment|neuron fate specification|positive regulation of oligodendrocyte differentiation|forebrain morphogenesis|subpallium neuron fate commitment|",DNA binding|sequence-specific DNA binding|,10,0.5,2.2,10,0.2,0.0424,0.4,1.75,1.75,0.488,0,0,-0.7,1.7
ENSMUSG00000069378,PRDM6,PR domain containing 6,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|neurogenesis|methylation|negative regulation of transcription, DNA-templated|negative regulation of smooth muscle cell differentiation|",nucleic acid binding|methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|protein homodimerization activity|metal ion binding|,10,-0.3,1.89,10,0.1,0.0945,-0.3,1.74,-1.74,0.49,0,0,-1.6,0.8
ENSMUSG00000073176,ZFP449,zinc finger protein 449,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|metal ion binding|,10,0,0,10,-0.3,2.06,-0.2,1.72,-1.72,0.493,0,0,-1.6,0.8
ENSMUSG00000041453,RPL21,ribosomal protein L21,intracellular|nucleolus|cytoplasm|ribosome|membrane|cytosolic large ribosomal subunit|ribonucleoprotein complex|,translation|,structural constituent of ribosome|poly(A) RNA binding|,3,0.9,2.87,2,-0.9,2.9,0.9,1.72,1.72,0.493,0,0,-1.7,2
ENSMUSG00000074607,TOX2,TOX high mobility group box family member 2,nucleus|,positive regulation of transcription from RNA polymerase II promoter|,RNA polymerase II transcription factor binding|,10,0.5,0.94,10,0.4,1.03,0.4,1.72,1.72,0.493,0,0,-0.8,1.7
ENSMUSG00000003233,DVL3,"dishevelled 3, dsh homolog (Drosophila)",cytoplasm|cell cortex|,"positive regulation of protein phosphorylation|heart morphogenesis|outflow tract septum morphogenesis|multicellular organismal development|Wnt signaling pathway|regulation of signaling|intracellular signal transduction|non-canonical Wnt signaling pathway|non-canonical Wnt signaling pathway via JNK cascade|positive regulation of JUN kinase activity|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|convergent extension|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|cochlea morphogenesis|planar cell polarity pathway involved in neural tube closure|",protease binding|receptor binding|frizzled binding|frizzled binding|protein binding|beta-catenin binding|beta-catenin binding|protein heterodimerization activity|,10,-0.4,1.55,10,-0.3,0.303,-0.3,1.69,-1.69,0.496,0,0,-1.7,0.6
ENSMUSG00000019782,RWDD1,RWD domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.322,10,-0.3,1.63,-0.2,1.69,-1.69,0.496,0,0,-1.7,0.6
ENSMUSG00000037477,TBX10,T-box 10,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,1,1.57,10,-0.5,1.92,-0.4,1.69,-1.69,0.496,0,0,-1.3,1.8
ENSMUSG00000018651,TADA2A,transcriptional adaptor 2A,PCAF complex|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|chromosome|mitotic spindle|,"regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|mitotic nuclear division|regulation of histone deacetylation|regulation of protein stability|histone H3 acetylation|regulation of tubulin deacetylation|",DNA binding|chromatin binding|histone acetyltransferase activity|,10,0.4,2.17,10,-0.5,2.89,0.3,1.69,1.69,0.496,0,0,-1.3,1.5
ENSMUSG00000048138,DMRT2,doublesex and mab-3 related transcription factor 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of somitogenesis|regulation of somitogenesis|embryonic skeletal system development|positive regulation of myotome development|",DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0.4,3.11,0.3,1.66,1.66,0.5,0,0,-0.9,1.7
ENSMUSG00000030543,MESP2,mesoderm posterior 2,nucleus|extracellular vesicular exosome|,"somitogenesis|somitogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|Notch signaling pathway|Notch signaling pathway|multicellular organismal development|mesodermal cell migration|signal transduction involved in regulation of gene expression|somite rostral/caudal axis specification|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein dimerization activity|,10,-0.1,0.205,10,-0.5,1.6,-0.5,1.66,-1.66,0.5,0,0,-1.8,0.4
ENSMUSG00000035456,PRDM8,PR domain containing 8,nucleus|histone methyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|histone methylation|peptidyl-lysine methylation|corpus callosum morphogenesis|central nervous system projection neuron axonogenesis|corticospinal tract morphogenesis|neurogenesis|methylation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|histone H3-K9 methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|DNA binding|chromatin binding|transcription corepressor activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|histone methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|histone methyltransferase activity (H3-K9 specific)|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.1,0.0951,10,0.4,2.17,0.3,1.65,1.65,0.502,0,0,-0.7,1.7
ENSMUSG00000062012,ZFP13,zinc finger protein 13,intracellular|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-templated|positive regulation of hydrogen peroxide biosynthetic process|positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|",nucleic acid binding|DNA binding|metal ion binding|,10,0.7,2.22,10,0.1,0.118,0.7,1.65,1.65,0.502,0,0,-0.3,1.9
ENSMUSG00000006456,RBM14,RNA binding motif protein 14,nucleus|transcription factor complex|,histone deacetylation|positive regulation of transcription from RNA polymerase II promoter|SMAD protein signal transduction|,ligand-dependent nuclear receptor transcription coactivator activity|poly(A) RNA binding|,5,0.5,0.393,4,0.8,1.69,0.6,1.65,1.65,0.502,0,0,-0.9,2
ENSMUSG00000021118,PLEK2,pleckstrin 2,cytoplasm|cytoskeleton|plasma membrane|membrane|cell projection|,intracellular signal transduction|,None,10,-0.5,2.05,10,-0.1,0.156,-0.5,1.63,-1.63,0.504,0,0,-1.7,0.9
ENSMUSG00000035910,DCDC2A,doublecortin domain containing 2a,cellular_component|,neuron migration|neuron migration|nervous system development|visual learning|intracellular signal transduction|dendrite morphogenesis|,molecular_function|,10,-0.3,1.26,10,-0.3,0.488,-0.3,1.62,-1.62,0.506,0,0,-1.6,0.9
ENSMUSG00000069273,HIST1H3E,"histone cluster 1, H3e",nuclear chromosome|chromatin|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|regulation of gene silencing|,molecular_function|,7,0,0,7,-0.3,2.7,-0.2,1.61,-1.61,0.507,0,0,-1.9,0.9
ENSMUSG00000041343,ANKRD42,ankyrin repeat domain 42,nucleus|,positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of cytokine production involved in inflammatory response|,NF-kappaB binding|,10,-0.3,1.44,10,-0.2,0.378,-0.3,1.61,-1.61,0.507,0,0,-1.7,0.8
ENSMUSG00000033210,SLC9C1,"solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1",plasma membrane|cilium|membrane|integral component of membrane|motile cilium|cell projection|,transport|ion transport|cation transport|sodium ion transport|multicellular organismal development|spermatogenesis|cell differentiation|sperm motility|transmembrane transport|,antiporter activity|solute:proton antiporter activity|,10,0,0,10,0.8,3.89,0.8,1.61,1.61,0.507,0,0,-0.2,2
ENSMUSG00000022724,MINA,myc induced nuclear antigen,nucleus|nucleus|transcription factor complex|nucleolus|cytoplasm|cytosol|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cell proliferation|regulation of cell proliferation|ribosome biogenesis|oxidation-reduction process|","sulfonate dioxygenase activity|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.5,1.58,10,0.2,0.698,0.4,1.58,1.58,0.511,0,0,-0.8,1.7
ENSMUSG00000020137,THAP2,"THAP domain containing, apoptosis associated protein 2",nucleolus|,biological_process|,molecular_function|nucleic acid binding|DNA binding|metal ion binding|,10,0.7,3.85,10,-0.3,1.16,0.6,1.58,1.58,0.511,0,0,-0.9,1.8
ENSMUSG00000041272,TOX,thymocyte selection-associated high mobility group box,nucleus|,None,DNA binding|,10,-0.3,1.07,10,-0.3,0.643,-0.3,1.58,-1.58,0.511,0,0,-1.6,0.8
ENSMUSG00000014426,MAP3K4,mitogen-activated protein kinase kinase kinase 4,cytoplasm|cytoplasm|,MAPK cascade|activation of MAPKK activity|placenta development|protein phosphorylation|response to UV-C|regulation of gene expression|phosphorylation|male germ-line sex determination|intracellular signal transduction|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|positive regulation of JUN kinase activity|determination of dorsal identity|chorionic trophoblast cell differentiation|positive regulation of p38MAPK cascade|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,0.4,2.38,10,0.1,0.0547,0.2,1.57,1.57,0.512,0,0,-0.7,1.8
ENSMUSG00000074771,ANKEF1,ankyrin repeat and EF-hand domain containing 1,cellular_component|,biological_process|,molecular_function|calcium ion binding|,10,-0.2,0.682,10,-0.5,1.21,-0.3,1.57,-1.57,0.512,0,0,-1.6,0.8
ENSMUSG00000034777,VAX2,ventral anterior homeobox 2,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|axonogenesis|dorsal/ventral axis specification|Wnt signaling pathway|forebrain development|camera-type eye development|embryonic eye morphogenesis|embryonic eye morphogenesis|retina development in camera-type eye|",DNA binding|chromatin DNA binding|sequence-specific DNA binding|,10,0.5,1.14,10,-0.4,3.41,-0.3,1.57,-1.57,0.512,0,0,-1.5,1.2
ENSMUSG00000040728,ESRP1,epithelial splicing regulatory protein 1,nucleus|,mRNA processing|RNA splicing|regulation of RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|,10,0.4,1.94,10,-0.3,2.63,-0.2,1.54,-1.54,0.517,0,0,-1.3,1.3
ENSMUSG00000051490,FOXD4,forkhead box D4,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.4,2.35,10,1.2,3.11,-0.3,1.53,-1.53,0.518,0,0,-1.1,2
ENSMUSG00000047888,TNRC6B,trinucleotide repeat containing 6b,cellular_component|cytoplasm|,"regulation of translation|gene silencing by RNA|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|",nucleotide binding|RNA binding|poly(A) RNA binding|,10,-0.3,0.743,10,-0.5,1.01,-0.3,1.53,-1.53,0.518,0,0,-1.5,1.5
ENSMUSG00000051375,PCDH1,protocadherin 1,plasma membrane|integral component of plasma membrane|cell-cell junction|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|calcium-dependent cell-cell adhesion|,protein binding|,10,0.4,0.249,10,0.4,1.38,0.4,1.51,1.51,0.521,0,0,-0.7,1.7
ENSMUSG00000058665,EN1,engrailed 1,nucleus|membrane|,"regulation of transcription, DNA-templated|multicellular organismal development|dorsal/ventral pattern formation|proximal/distal pattern formation|regulation of gene expression|regulation of gene expression|neuron differentiation|embryonic limb morphogenesis|embryonic limb morphogenesis|midbrain development|hindbrain development|midbrain-hindbrain boundary development|embryonic forelimb morphogenesis|multicellular organism growth|pigmentation|positive regulation of transcription from RNA polymerase II promoter|neuron development|neuron development|limb development|",DNA binding|protein binding|sequence-specific DNA binding|,10,0.3,1.79,10,0.1,0.221,0.2,1.51,1.51,0.521,0,0,-1.2,1.4
ENSMUSG00000075000,NRBF2,nuclear receptor binding factor 2,nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|",transcription coactivator activity|ligand-dependent nuclear receptor binding|,10,-0.2,0.55,10,-0.3,1.19,-0.2,1.5,-1.5,0.522,0,0,-1.7,0.7
ENSMUSG00000074088,SNRNP40,small nuclear ribonucleoprotein 40 (U5),nucleus|spliceosomal complex|cytoplasm|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,poly(A) RNA binding|,10,0,0,9,0.4,2.3,0.3,1.49,1.49,0.524,0,0,-0.9,1.7
ENSMUSG00000052928,CTIF,CBP80/20-dependent translation initiation factor,cytoplasm|perinuclear region of cytoplasm|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of translation|regulation of translational initiation|",molecular_function|RNA binding|,10,-0.8,4.5,10,0.1,0.198,-0.8,1.49,-1.49,0.524,0,0,-2,0.4
ENSMUSG00000049295,ZFP219,zinc finger protein 219,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.7,1.43,10,-0.2,0.977,-0.2,1.48,-1.48,0.526,0,0,-2,0.8
ENSMUSG00000053007,CREB5,cAMP responsive element binding protein 5,nucleus|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|fat cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|adipose tissue development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,-1.2,4.49,-1.2,1.48,-1.48,0.526,0,0,-2,0.2
ENSMUSG00000026890,LHX6,LIM homeobox protein 6,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|cerebral cortex radially oriented cell migration|cerebral cortex tangential migration|cerebral cortex GABAergic interneuron migration|forebrain neuron fate commitment|forebrain neuron development|cerebral cortex neuron differentiation|cell differentiation|cell maturation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.3,0.595,10,0.5,3.17,0.4,1.47,1.47,0.527,0,0,-1.2,1.6
ENSMUSG00000038500,PRR3,proline-rich polypeptide 3,cellular_component|,biological_process|,poly(A) RNA binding|metal ion binding|,10,0.5,0.924,10,0.3,0.868,0.3,1.45,1.45,0.53,0,0,-0.6,1.7
ENSMUSG00000054385,CEACAM2,carcinoembryonic antigen-related cell adhesion molecule 2,plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,viral process|negative regulation of brown fat cell proliferation|negative regulation of feeding behavior|regulation of energy homeostasis|,protein kinase binding|protein homodimerization activity|,10,0.1,0.0455,10,0.5,1.83,0.5,1.44,1.44,0.532,0,0,-0.8,1.7
ENSMUSG00000022176,REM2,rad and gem related GTP binding protein 2,plasma membrane|membrane|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|,nucleotide binding|GTPase activity|GTP binding|,10,-0.1,0.226,10,-1.3,3.02,-0.3,1.43,-1.43,0.533,0,0,-2,0.6
ENSMUSG00000035049,RRP12,ribosomal RNA processing 12 homolog (S. cerevisiae),nucleus|nucleolus|membrane|integral component of membrane|,biological_process|,poly(A) RNA binding|,9,-0.2,0.903,8,1,3.33,0.6,1.42,1.42,0.535,0,0,-0.7,2
ENSMUSG00000058794,NFE2,"nuclear factor, erythroid derived 2",nucleus|nucleus|cytoplasm|actin cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell-cell signaling|negative regulation of bone mineralization|negative regulation of syncytium formation by plasma membrane fusion|negative regulation of syncytium formation by plasma membrane fusion|labyrinthine layer blood vessel development|positive regulation of peptidyl-lysine acetylation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|protein N-terminus binding|WW domain binding|,10,-0.3,0.389,10,-0.2,1.28,-0.2,1.41,-1.41,0.536,0,0,-1.6,1.2
ENSMUSG00000046229,SCAND1,SCAN domain-containing 1,nucleus|nucleus|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|regulation of RNA biosynthetic process|,sequence-specific DNA binding RNA polymerase II transcription factor activity|transcription coactivator activity|,10,0.5,1.65,10,0.3,0.0569,0.5,1.38,1.38,0.541,0,0,-0.5,1.8
ENSMUSG00000063894,ZKSCAN8,zinc finger with KRAB and SCAN domains 8,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|metal ion binding|,10,-0.6,2.42,10,-0.1,0.084,-0.2,1.37,-1.37,0.542,0,0,-1.9,0.8
ENSMUSG00000047034,ANKRD33,ankyrin repeat domain 33,nucleus|cytosol|,negative regulation of transcription from RNA polymerase II promoter|skeletal muscle cell differentiation|negative regulation of transcription regulatory region DNA binding|,molecular_function|,10,0,0,10,-1.2,4.24,-1.2,1.37,-1.37,0.542,0,0,-2,1
ENSMUSG00000069114,ZBTB10,zinc finger and BTB domain containing 10,nucleus|,negative regulation of transcription from RNA polymerase II promoter|,DNA binding|metal ion binding|,10,0.1,0.101,10,-0.4,1.41,-0.4,1.37,-1.37,0.542,0,0,-1.7,1.1
ENSMUSG00000078173,LENEP,lens epithelial protein,cytoplasm|,multicellular organismal development|biological_process|,molecular_function|,10,-0.3,0.755,10,-0.5,0.991,-0.4,1.36,-1.36,0.544,0,0,-1.9,0.5
ENSMUSG00000021990,SPATA13,spermatogenesis associated 13,nucleus|cytoplasm|plasma membrane|membrane|lamellipodium|filopodium|ruffle membrane|cell projection|,cell migration|lamellipodium assembly|regulation of cell migration|positive regulation of Rac GTPase activity|regulation of Rho protein signal transduction|intracellular signal transduction|positive regulation of GTPase activity|filopodium assembly|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|Rac guanyl-nucleotide exchange factor activity|,10,0,0,10,-0.4,2.12,-0.2,1.35,-1.35,0.545,0,0,-1.8,0.6
ENSMUSG00000037921,DDX60,DEAD (Asp-Glu-Ala-Asp) box polypeptide 60,cytoplasm|cytoplasm|intermediate filament cytoskeleton|,response to virus|defense response to virus|positive regulation of MDA-5 signaling pathway|positive regulation of RIG-I signaling pathway|,nucleotide binding|double-stranded DNA binding|RNA binding|double-stranded RNA binding|single-stranded RNA binding|helicase activity|protein binding|ATP binding|hydrolase activity|,10,0.3,1.62,10,0.1,0.223,0.2,1.35,1.35,0.545,0,0,-0.9,1.6
ENSMUSG00000018974,SART3,squamous cell carcinoma antigen recognized by T cells 3,intracellular|nucleus|cytoplasm|,cell morphogenesis|RNA processing|regulation of gene expression|homeostasis of number of cells|hematopoietic stem cell proliferation|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.2,0.42,10,0.6,1.21,0.4,1.34,1.34,0.547,0,0,-1.2,1.6
ENSMUSG00000057469,E2F6,E2F transcription factor 6,nucleus|DNA replication factor A complex|transcription factor complex|MLL1 complex|,"regulation of transcription involved in G1/S transition of mitotic cell cycle|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.4,1.14,10,-0.2,0.486,-0.2,1.34,-1.34,0.547,0,0,-1.8,0.6
ENSMUSG00000041935,AW549877,expressed sequence AW549877,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0844,10,-0.2,1.43,-0.2,1.33,-1.33,0.548,0,0,-1.5,1.2
ENSMUSG00000033430,TERF2IP,"telomeric repeat binding factor 2, interacting protein","chromosome, telomeric region|chromosome, telomeric region|chromosome, telomeric region|nuclear telomere cap complex|nuclear chromosome, telomeric region|nuclear chromosome, telomeric region|nucleus|nucleus|nuclear envelope|chromosome|cytoplasm|cytoplasm|Mre11 complex|","telomere maintenance|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of double-strand break repair via homologous recombination|telomere maintenance via telomere lengthening|negative regulation of telomere maintenance|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of DNA recombination at telomere|positive regulation of NF-kappaB transcription factor activity|protein localization to chromosome, telomeric region|",DNA binding|protein binding|,10,0.5,1.55,10,0.1,0.227,0.3,1.33,1.33,0.548,0,0,-0.4,1.9
ENSMUSG00000036120,RFXANK,regulatory factor X-associated ankyrin-containing protein,intracellular|nucleus|nucleus|nucleus|cytoplasm|cytoplasm|intercellular bridge|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Ras protein signal transduction|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|protein binding|histone deacetylase binding|,10,-0.3,1.12,10,-0.1,0.531,-0.2,1.3,-1.3,0.553,0,0,-1.7,0.9
ENSMUSG00000016181,DIEXF,digestive organ expansion factor homolog (zebrafish),cellular_component|nucleus|,multicellular organismal development|biological_process|,poly(A) RNA binding|,10,-0.1,0.192,10,1.7,4.23,1.6,1.3,1.3,0.553,0,0,-0.5,3
ENSMUSG00000011349,DMRTC2,doublesex and mab-3 related transcription factor like family C2,XY body|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|male meiosis I|spermatid nucleus elongation|sex differentiation|cell differentiation|positive regulation of histone H3-K9 dimethylation|positive regulation of histone H3-K9 trimethylation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|,10,-0.2,0.325,10,-1.3,2.58,-0.3,1.27,-1.27,0.558,0,0,-2,0.8
ENSMUSG00000037058,PAIP2,polyadenylate-binding protein-interacting protein 2,cytoplasm|cytoplasm|,regulation of translation|spermatogenesis|memory|negative regulation of translation|negative regulation of translation|negative regulation of translational initiation|regulation of long-term synaptic potentiation|,"translation repressor activity, nucleic acid binding|mRNA binding|poly(A) binding|translation repressor activity|",10,-0.7,3.53,10,0,0,-0.3,1.25,-1.25,0.562,0,0,-2,0.5
ENSMUSG00000035356,NFKBIZ,"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|inflammatory response|",None,10,0,0,10,-0.8,3.84,-0.7,1.25,-1.25,0.562,0,0,-2,0.4
ENSMUSG00000038151,PRDM1,"PR domain containing 1, with ZNF domain",nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|embryonic placenta development|maternal placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|germ cell development|post-embryonic development|positive regulation of gene expression|negative regulation of gene expression|negative regulation of B cell proliferation|negative regulation of lipopolysaccharide-mediated signaling pathway|methylation|eye photoreceptor cell development|cell fate commitment|positive regulation of B cell differentiation|intestinal epithelial cell development|trophoblast giant cell differentiation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|DNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|histone deacetylase binding|sequence-specific DNA binding|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.2,0.928,10,0.2,0.414,0.2,1.24,1.24,0.563,0,0,-0.7,1.8
ENSMUSG00000030188,MAGOHB,mago-nashi homolog B (Drosophila),cellular_component|nucleus|,mRNA processing|transport|biological_process|RNA splicing|mRNA transport|,RNA binding|poly(A) RNA binding|,10,0.3,0.758,10,0.3,0.586,0.3,1.24,1.24,0.563,0,0,-0.6,1.8
ENSMUSG00000063821,DUPD1,dual specificity phosphatase and pro isomerase domain containing 1,cellular_component|cytoplasm|,protein dephosphorylation|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,0.1,0.00649,10,0.2,1.31,0.2,1.22,1.22,0.567,0,0,-0.7,1.8
ENSMUSG00000000916,NSUN5,"NOL1/NOP2/Sun domain family, member 5",nucleus|nucleolus|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.1,0.121,10,0.5,2.01,0.3,1.22,1.22,0.567,0,0,-1.2,1.7
ENSMUSG00000023284,ZFP605,zinc finger protein 605,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.7,2.35,10,-0.1,0.0781,-0.6,1.22,-1.22,0.567,0,0,-2,0.4
ENSMUSG00000019564,ARID3A,AT rich interactive domain 3A (BRIGHT-like),intracellular|nucleus|nucleus|cytoplasm|Golgi apparatus|membrane raft|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|,9,0.2,0.209,9,0.4,1.39,0.3,1.21,1.21,0.568,0,0,-1,1.8
ENSMUSG00000028565,NFIA,nuclear factor I/A,intracellular|nucleus|nucleus|,"DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|,10,-0.3,1.96,10,-0.1,0.103,-0.3,1.2,-1.2,0.57,0,0,-1.8,0.7
ENSMUSG00000041309,NKX6-2,NK6 homeobox 2,nucleus|nucleus|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of cell fate commitment|positive regulation of cell fate commitment|regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification|regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification|central nervous system myelination|cell differentiation|endocrine pancreas development|negative regulation of glial cell differentiation|positive regulation of glial cell differentiation|oligodendrocyte differentiation|neuromuscular process controlling balance|,DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.5,2.18,10,0.3,0.263,-0.2,1.2,-1.2,0.57,0,0,-1.8,1
ENSMUSG00000068284,GM608,predicted gene 608,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.228,10,-0.3,1.14,-0.2,1.19,-1.19,0.572,0,0,-1.7,0.8
ENSMUSG00000031681,SMAD1,SMAD family member 1,intracellular|nucleus|nucleus|nuclear inner membrane|transcription factor complex|cytoplasm|cytoplasm|mitochondrion|protein complex|,"MAPK cascade|MAPK cascade|mesodermal cell fate commitment|osteoblast fate commitment|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|protein phosphorylation|transforming growth factor beta receptor signaling pathway|SMAD protein complex assembly|gamete generation|negative regulation of cell proliferation|positive regulation of gene expression|positive regulation of gene expression|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|midbrain development|hindbrain development|response to drug|homeostatic process|positive regulation of cell differentiation|positive regulation of osteoblast differentiation|positive regulation of transcription from RNA polymerase II promoter|cartilage development|cardiac muscle cell proliferation|cardiac muscle cell proliferation|bone development|positive regulation of cartilage development|cellular response to organic cyclic compound|cellular response to BMP stimulus|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein kinase binding|identical protein binding|metal ion binding|co-SMAD binding|I-SMAD binding|,10,0.1,0.00142,10,0.4,1.43,0.4,1.17,1.17,0.575,0,0,-0.7,1.8
ENSMUSG00000043372,HEXIM2,hexamethylene bis-acetamide inducible 2,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of transcription, DNA-templated|",cyclin-dependent protein serine/threonine kinase inhibitor activity|snRNA binding|,10,0,0,10,0.4,1.67,0.3,1.16,1.16,0.577,0,0,-1.4,1.4
ENSMUSG00000041420,MEIS3,Meis homeobox 3,nucleus|,"regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein kinase B signaling|negative regulation of apoptotic signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding|,10,-0.2,0.47,10,-0.3,0.783,-0.2,1.13,-1.13,0.582,0,0,-1.5,1.1
ENSMUSG00000038025,PHF2,PHD finger protein 2,nucleus|nucleolus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein demethylation|chromatin modification|histone H3-K9 demethylation|histone H3-K9 demethylation|oxidation-reduction process|negative regulation of chromatin silencing at rDNA|","sulfonate dioxygenase activity|transcription coactivator activity|iron ion binding|zinc ion binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|histone demethylase activity (H3-K9 specific)|histone demethylase activity (H3-K9 specific)|hypophosphite dioxygenase activity|methylated histone binding|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.1,0.0787,10,-0.6,2.23,-0.4,1.13,-1.13,0.582,0,0,-1.9,0.6
ENSMUSG00000055065,DDX17,DEAD (Asp-Glu-Ala-Asp) box polypeptide 17,nucleus|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|post-embryonic development|positive regulation of intracellular estrogen receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|cardiovascular system development|regulation of skeletal muscle cell differentiation|",nucleotide binding|nucleic acid binding|transcription coactivator activity|RNA binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|estrogen receptor binding|poly(A) RNA binding|,10,0,0,10,0.3,1.84,0.2,1.13,1.13,0.582,0,0,-0.8,1.7
ENSMUSG00000045555,METTL24,methyltransferase like 24,cellular_component|extracellular region|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.2,0.355,10,0.3,0.963,0.2,1.12,1.12,0.584,0,0,-1.2,1.5
ENSMUSG00000054191,KLF1,Kruppel-like factor 1 (erythroid),nuclear chromatin|nucleus|,"in utero embryonic development|liver development|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|erythrocyte differentiation|embryonic hemopoiesis|erythrocyte maturation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|erythrocyte development|",core promoter proximal region sequence-specific DNA binding|nucleic acid binding|DNA binding|protein domain specific binding|activating transcription factor binding|transcription regulatory region DNA binding|metal ion binding|,10,-0.3,1.9,10,0,0,-0.2,1.11,-1.11,0.586,0,0,-1.7,0.7
ENSMUSG00000093668,POU5F2,"POU domain class 5, transcription factor 2",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.2,1.53,10,0,0,-0.2,1.09,-1.09,0.589,0,0,-1.8,0.6
ENSMUSG00000079277,HOXD3,homeobox D3,None,"transcription, DNA-templated|cell-matrix adhesion|Notch signaling pathway|anterior/posterior pattern specification|anterior/posterior pattern specification|positive regulation of gene expression|glossopharyngeal nerve morphogenesis|thyroid gland development|positive regulation of neuron differentiation|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|cartilage development|",None,10,0.2,0.389,10,1,2.05,0.3,1.09,1.09,0.589,0,0,-0.4,2
ENSMUSG00000053129,GSX1,GS homeobox 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|spinal cord association neuron differentiation|hypothalamus development|adenohypophysis development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|neuron fate commitment|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,-0.2,0.129,10,-0.4,1.36,-0.3,1.08,-1.08,0.59,0,0,-1.7,0.8
ENSMUSG00000034993,VAT1,vesicle amine transport protein 1 homolog (T californica),cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|extracellular vesicular exosome|,negative regulation of mitochondrial fusion|oxidation-reduction process|,zinc ion binding|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,-0.5,2.28,10,0,0,-0.3,1.07,-1.07,0.592,0,0,-1.9,0.5
ENSMUSG00000091854,MIER2,"mesoderm induction early response 1, family member 2",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|chromatin binding|,10,0,0,10,0.5,1.99,0.3,1.07,1.07,0.592,0,0,-0.6,2
ENSMUSG00000042197,ZFP451,zinc finger protein 451,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0.1,0.151,10,-0.3,2.2,-0.2,1.06,-1.06,0.594,0,0,-1.5,1.2
ENSMUSG00000047036,ZFP445,zinc finger protein 445,intracellular|nucleus|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.279,10,-0.6,3.37,-0.4,1.05,-1.05,0.596,0,0,-1.8,0.7
ENSMUSG00000034007,SCAPER,S phase cyclin A-associated protein in the ER,cellular_component|,biological_process|,molecular_function|,10,0.3,0.183,9,-0.3,1.37,-0.2,1.05,-1.05,0.596,0,0,-1.3,1.6
ENSMUSG00000061136,PRPF40A,PRP40 pre-mRNA processing factor 40 homolog A (yeast),nucleus|cytoplasm|membrane|nuclear matrix|nuclear matrix|,mRNA processing|cytoskeleton organization|regulation of cell shape|RNA splicing|cell migration|regulation of cytokinesis|,protein binding|poly(A) RNA binding|proline-rich region binding|,7,0.2,0.33,8,0.9,1.58,0.3,1.04,1.04,0.598,0,0,-0.9,2
ENSMUSG00000001911,NFIX,nuclear factor I/X,intracellular|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|cerebellum development|cerebellar Purkinje cell layer development|cerebellar granule cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|astrocyte differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.2,0.279,10,-0.3,1.08,-0.2,1.04,-1.04,0.598,0,0,-1.5,1.1
ENSMUSG00000022484,HOXC10,homeobox C10,nucleus|cyclin-dependent protein kinase activating kinase holoenzyme complex|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|proximal/distal pattern formation|spinal cord motor neuron cell fate specification|embryonic limb morphogenesis|neuromuscular process|",DNA binding|sequence-specific DNA binding|,10,-0.5,0.715,10,0.6,2.39,0.3,1.04,1.04,0.598,0,0,-1.1,1.8
ENSMUSG00000034780,B3GALT1,"UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1",Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|oligosaccharide biosynthetic process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,-0.5,2.19,-0.3,1.03,-1.03,0.6,0,0,-1.7,0.9
ENSMUSG00000059208,HNRNPM,heterogeneous nuclear ribonucleoprotein M,nucleus|nucleoplasm|spliceosomal complex|membrane|nuclear matrix|ribonucleoprotein complex|paraspeckles|catalytic step 2 spliceosome|,"alternative mRNA splicing, via spliceosome|mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|antigen binding|protein domain specific binding|poly(A) RNA binding|,9,-0.2,0.0421,9,-1,1.98,-0.2,1.03,-1.03,0.6,0,0,-2,0.6
ENSMUSG00000028522,MIER1,mesoderm induction early response 1 homolog (Xenopus laevis,nucleus|transcriptional repressor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|positive regulation of chromatin silencing|positive regulation of I-kappaB kinase/NF-kappaB signaling|",DNA binding|chromatin binding|signal transducer activity|,10,-0.2,0.595,10,-0.1,0.59,-0.1,1.02,-1.02,0.602,0,0,-1.6,1.1
ENSMUSG00000022557,BOP1,block of proliferation 1,nucleus|nucleolus|ribonucleoprotein complex|PeBoW complex|,"cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|rRNA processing|rRNA processing|cell proliferation|ribosome biogenesis|ribosomal large subunit biogenesis|regulation of cell cycle|",protein binding|ribonucleoprotein complex binding|poly(A) RNA binding|,10,-0.2,0.458,9,-0.2,0.653,-0.2,1.02,-1.02,0.602,0,0,-1.7,0.9
ENSMUSG00000026610,ESRRG,estrogen-related receptor gamma,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|intracellular receptor signaling pathway|steroid hormone mediated signaling pathway|positive regulation of transcription, DNA-templated|retinoic acid receptor signaling pathway|",DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|retinoic acid receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|steroid binding|protein binding|calmodulin binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,-0.3,1.45,10,0.7,1.57,-0.2,1.01,-1.01,0.604,0,0,-1.2,1.8
ENSMUSG00000027796,SMAD9,SMAD family member 9,intracellular|nucleus|transcription factor complex|cytoplasm|,"Mullerian duct regression|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|transforming growth factor beta receptor signaling pathway|BMP signaling pathway|BMP signaling pathway|midbrain development|hindbrain development|positive regulation of cell differentiation|positive regulation of transcription, DNA-templated|cartilage development|bone development|cellular response to organic cyclic compound|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,-0.1,0.104,10,-0.2,1.14,-0.2,1.01,-1.01,0.604,0,0,-1.6,1.1
ENSMUSG00000024619,CDX1,caudal type homeobox 1,nucleus|,"regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|pattern specification process|anterior/posterior pattern specification|anterior/posterior pattern specification|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|bone morphogenesis|bone morphogenesis|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|,10,0,0,10,-0.2,1.5,-0.2,1,-1,0.606,0,0,-1.5,1.5
ENSMUSG00000021144,MTA1,metastasis associated 1,nucleus|nucleus|cytoplasm|cytoplasm|endoplasmic reticulum|Golgi apparatus|NuRD complex|intracellular membrane-bounded organelle|,"regulation of transcription, DNA-templated|secretory granule organization|",RNA polymerase II repressing transcription factor binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|enzyme binding|sequence-specific DNA binding|metal ion binding|,10,-0.5,2.05,10,0.1,0.0139,-0.6,0.995,-0.995,0.606,0,0,-2,0.4
ENSMUSG00000027498,CSTF1,"cleavage stimulation factor, 3' pre-RNA, subunit 1",cellular_component|nucleus|,mRNA processing|,poly(A) RNA binding|,9,0.2,1.15,9,0.1,0.0314,0.2,0.994,0.994,0.607,0,0,-1.1,1.7
ENSMUSG00000045969,ING1,"inhibitor of growth family, member 1",nucleus|,"protein import into nucleus|cell cycle|negative regulation of cell proliferation|regulation of cell death|chromatin modification|positive regulation of transcription, DNA-templated|",zinc ion binding|methylated histone binding|metal ion binding|,10,-0.1,0.449,10,-0.2,0.666,-0.2,0.987,-0.987,0.608,0,0,-1.7,0.9
ENSMUSG00000037331,LARP1,"La ribonucleoprotein domain family, member 1",nucleus|cytoplasm|cytoplasm|membrane|TORC1 complex|,translational initiation|cell proliferation|positive regulation of macroautophagy|TOR signaling|positive regulation of translation|,RNA cap binding|RNA binding|mRNA 3'-UTR binding|eukaryotic initiation factor 4E binding|translation activator activity|translation initiation factor binding|poly(A) RNA binding|mRNA 5'-UTR binding|,8,-0.2,0.344,9,0.5,1.63,0.5,0.969,0.969,0.611,0,0,-0.9,1.8
ENSMUSG00000027544,NFATC2,"nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2",nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytosol|cytosol|plasma membrane|actin cytoskeleton|ribonucleoprotein complex|nuclear transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|positive regulation of gene expression|cell migration|positive regulation of B cell proliferation|response to drug|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|B cell receptor signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|,9,-0.8,2.74,9,1.3,2.04,-0.3,0.966,-0.966,0.612,0,0,-1.8,1.8
ENSMUSG00000021506,PITX1,paired-like homeodomain transcription factor 1,nucleus|nucleus|transcription factor complex|nucleolus|cytoplasm|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|branchiomeric skeletal muscle development|pituitary gland development|embryonic hindlimb morphogenesis|hindlimb morphogenesis|hindlimb morphogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|myoblast fate commitment|cartilage development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.3,2.02,0.3,0.959,0.959,0.613,0,0,-0.7,1.8
ENSMUSG00000015501,HIVEP2,human immunodeficiency virus type I enhancer binding protein 2,nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.174,10,0.3,0.904,0.2,0.956,0.956,0.614,0,0,-0.9,1.7
ENSMUSG00000037492,ZMAT4,"zinc finger, matrin type 4",nucleus|,biological_process|,nucleic acid binding|DNA binding|zinc ion binding|metal ion binding|,10,-0.6,0.824,10,-0.2,0.692,-0.3,0.953,-0.953,0.614,0,0,-1.7,1.5
ENSMUSG00000024803,ANKRD1,ankyrin repeat domain 1 (cardiac muscle),nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytosol|myofibril|I band|I band|,"negative regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of neuron projection development|cellular response to drug|skeletal muscle cell differentiation|response to muscle stretch|positive regulation of apoptotic process|positive regulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein secretion|cardiac muscle tissue morphogenesis|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|cellular response to mechanical stimulus|cellular response to interleukin-1|cellular response to tumor necrosis factor|cellular response to transforming growth factor beta stimulus|negative regulation of DNA biosynthetic process|",RNA polymerase II transcription factor binding|RNA polymerase II transcription coactivator activity|p53 binding|DNA binding|transcription corepressor activity|protein binding|transcription factor binding|titin binding|titin binding|histone deacetylase binding|R-SMAD binding|,10,-0.2,0.545,10,-0.2,0.489,-0.2,0.95,-0.95,0.615,0,0,-1.2,1.7
ENSMUSG00000029736,NOBOX,NOBOX oogenesis homeobox,nucleus|transcription factor complex|cytoplasm|,"ovarian follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|oogenesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,9,0.5,1.26,9,-0.3,1.79,0.3,0.948,0.948,0.615,0,0,-1.1,1.6
ENSMUSG00000036602,ALX1,ALX homeobox 1,nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|neural tube closure|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|anterior/posterior pattern specification|mesenchymal cell development|embryonic limb morphogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|palate development|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|protein heterodimerization activity|,10,-0.6,3.43,10,0.1,0.14,0.3,0.947,0.947,0.615,0,0,-1.8,1.2
ENSMUSG00000027430,DTD1,D-tyrosyl-tRNA deacylase 1,nucleus|cytoplasm|,DNA replication|biological_process|D-amino acid catabolic process|,"molecular_function|DNA binding|nuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|",10,1.8,2.2,10,0.4,2.05,1.7,0.942,0.942,0.616,0,0,-0.2,3
ENSMUSG00000033726,EMX1,empty spiracles homeobox 1,nucleus|,"in utero embryonic development|regulation of transcription, DNA-templated|multicellular organismal development|brain development|post-embryonic development|cerebral cortex regionalization|cerebral cortex neuron differentiation|cerebral cortex development|cerebral cortex development|neuron differentiation|response to drug|brain morphogenesis|neuron projection extension|",DNA binding|sequence-specific DNA binding|,10,-0.4,0.275,10,1.1,1.59,0.6,0.939,0.939,0.617,0,0,-0.9,2
ENSMUSG00000027201,MYEF2,"myelin basic protein expression factor 2, repressor",nucleus|cytoplasm|,None,poly(A) RNA binding|,10,0,0,10,-0.3,2.53,-0.3,0.936,-0.936,0.618,0,0,-1.7,1.1
ENSMUSG00000026279,THAP4,THAP domain containing 4,cellular_component|,biological_process|,molecular_function|nucleic acid binding|DNA binding|metal ion binding|,10,0.4,0.525,10,0.2,0.588,0.2,0.924,0.924,0.62,0,0,-0.8,1.8
ENSMUSG00000000838,FMR1,fragile X mental retardation syndrome 1,nucleus|cytoplasm|polysome|mRNA cap binding complex|microtubule|cytoplasmic stress granule|membrane|dendrite|cytoplasmic ribonucleoprotein granule|neuron projection|dendritic spine|dendritic shaft|cell body|synapse|neuronal ribonucleoprotein granule|neuronal ribonucleoprotein granule|,transport|central nervous system development|negative regulation of translational initiation|mRNA transport|,RNA binding|protein binding|microtubule binding|poly(A) RNA binding|,10,0,0,10,-0.2,1.33,-0.2,0.918,-0.918,0.621,0,0,-1.6,1
ENSMUSG00000048626,KLF17,Kruppel-like factor 17,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|gamete generation|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,-0.4,2.84,-0.4,0.906,-0.906,0.623,0,0,-1.8,0.7
ENSMUSG00000078202,NRARP,Notch-regulated ankyrin repeat protein,cellular_component|,negative regulation of transcription from RNA polymerase II promoter|patterning of blood vessels|patterning of blood vessels|positive regulation of endothelial cell proliferation|sprouting angiogenesis|sprouting angiogenesis|blood vessel endothelial cell proliferation involved in sprouting angiogenesis|multicellular organismal development|regulation of cell-cell adhesion|regulation of cell-cell adhesion|somite rostral/caudal axis specification|negative regulation of T cell differentiation|negative regulation of Notch signaling pathway|negative regulation of Notch signaling pathway|negative regulation of Notch signaling pathway|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|negative regulation of Notch signaling pathway involved in somitogenesis|,None,10,0,0,10,-0.6,2.01,-0.2,0.9,-0.9,0.625,0,0,-1.8,0.8
ENSMUSG00000043424,EIF3J2,"eukaryotic translation initiation factor 3, subunit J2",eukaryotic translation initiation factor 3 complex|,biological_process|,molecular_function|,8,0.3,0.846,9,-0.8,0.529,-0.4,0.89,-0.89,0.627,0,0,-1.9,1
ENSMUSG00000020733,SLC9A3R1,"solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1",intracellular|cytoplasm|centrosome|plasma membrane|microvillus|membrane|membrane|apical plasma membrane|apical plasma membrane|brush border membrane|microvillus membrane|cell projection|intracellular membrane-bounded organelle|membrane raft|apical part of cell|extracellular vesicular exosome|cell periphery|sperm midpiece|,renal sodium ion transport|adenylate cyclase-activating dopamine receptor signaling pathway|negative regulation of cell proliferation|negative regulation of platelet-derived growth factor receptor signaling pathway|negative regulation of sodium ion transport|negative regulation of phosphatidylinositol 3-kinase signaling|negative regulation of phosphatidylinositol 3-kinase signaling|Wnt signaling pathway|cAMP-mediated signaling|cAMP-mediated signaling|microvillus assembly|actin cytoskeleton organization|negative regulation of cell migration|cellular phosphate ion homeostasis|negative regulation of sodium:proton antiporter activity|bile acid secretion|cellular protein localization|glutathione transport|regulation of excretion|regulation of protein kinase activity|negative regulation of protein kinase B signaling|negative regulation of protein kinase B signaling|phospholipase C-activating dopamine receptor signaling pathway|renal absorption|negative regulation of ERK1 and ERK2 cascade|renal phosphate ion absorption|negative regulation of cell motility|positive regulation of intrinsic apoptotic signaling pathway|,receptor binding|protein binding|beta-catenin binding|chloride channel regulator activity|phosphatase binding|phosphatase binding|protein domain specific binding|PDZ domain binding|beta-2 adrenergic receptor binding|protein complex binding|protein complex scaffold|protein self-association|dopamine receptor binding|growth factor receptor binding|,10,-0.3,0.836,10,0.4,2.2,0.3,0.887,0.887,0.627,0,0,-1.4,1.4
ENSMUSG00000030515,TARSL2,threonyl-tRNA synthetase-like 2,cytoplasm|,translation|tRNA aminoacylation for protein translation|threonyl-tRNA aminoacylation|tRNA aminoacylation|,"nucleotide binding|aminoacyl-tRNA ligase activity|threonine-tRNA ligase activity|ATP binding|ligase activity|ligase activity, forming aminoacyl-tRNA and related compounds|",10,0.3,0.597,10,0.3,0.363,0.3,0.882,0.882,0.628,0,0,-1.1,1.6
ENSMUSG00000039652,CPEB3,cytoplasmic polyadenylation element binding protein 3,nucleus|nucleus|cytoplasm|cytoplasm|CCR4-NOT complex|dendrite|neuron projection|neuron projection|synapse|apical dendrite|,"negative regulation of transcription from RNA polymerase II promoter|translation|translation|long-term memory|negative regulation of translation|negative regulation of translation|negative regulation of translation|positive regulation of translation|regulation of synaptic plasticity|positive regulation of nuclear-transcribed mRNA poly(A) tail shortening|regulation of dendritic spine development|positive regulation of dendritic spine development|3'-UTR-mediated mRNA destabilization|cellular response to amino acid stimulus|cellular response to amino acid stimulus|positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|negative regulation of cytoplasmic translational elongation|positive regulation of mRNA polyadenylation|","nucleotide binding|translation repressor activity, nucleic acid binding|nucleic acid binding|RNA binding|RNA binding|mRNA 3'-UTR binding|mRNA 3'-UTR binding|protein binding|translation factor activity, nucleic acid binding|translation factor activity, nucleic acid binding|RNA stem-loop binding|mRNA 3'-UTR AU-rich region binding|poly(A) RNA binding|",10,0.3,0.746,10,-0.4,1.46,-0.3,0.868,-0.868,0.631,0,0,-1.4,1.3
ENSMUSG00000040363,BCOR,BCL6 interacting corepressor,nucleus|nucleus|PcG protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of histone H3-K36 methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|chromatin modification|negative regulation of bone mineralization|histone H2A monoubiquitination|odontogenesis|negative regulation of transcription, DNA-templated|negative regulation of histone H3-K4 methylation|palate development|specification of axis polarity|negative regulation of tooth mineralization|regulation of RNA biosynthetic process|",transcription corepressor activity|transcription corepressor activity|ubiquitin-protein transferase activity|protein binding|transcription factor binding|heat shock protein binding|histone deacetylase binding|transcription regulatory region DNA binding|,10,0,0,10,-0.2,1.25,-0.2,0.86,-0.86,0.633,0,0,-1.7,1
ENSMUSG00000032320,RCN2,reticulocalbin 2,nucleolus|endoplasmic reticulum|,None,calcium ion binding|protein binding|metal ion binding|,10,-0.8,2.5,10,0.2,0.372,0.2,0.853,0.853,0.634,0,0,-2,1
ENSMUSG00000060510,ZFP266,zinc finger protein 266,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.2,0.401,10,0.2,0.945,0.2,0.841,0.841,0.636,0,0,-1.2,1.6
ENSMUSG00000056895,HIST3H2BA,"histone cluster 3, H2ba",nucleosome|nucleus|chromosome|extracellular vesicular exosome|,biological_process|,DNA binding|protein heterodimerization activity|,10,0.5,1.79,10,-0.3,0.618,0.5,0.838,0.838,0.637,0,0,-1.2,1.7
ENSMUSG00000068959,ZFP619,zinc finger protein 619,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.2,1.6,10,-0.2,0.214,0.2,0.834,0.834,0.638,0,0,-1.4,1.5
ENSMUSG00000035051,DHX57,DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|metal ion binding|,10,0.8,2.88,10,0,0,0.2,0.831,0.831,0.638,0,0,-0.7,1.9
ENSMUSG00000012350,EHF,ets homologous factor,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.3,0.923,10,-0.2,0.203,-0.2,0.828,-0.828,0.639,0,0,-1.5,1.2
ENSMUSG00000031688,POU4F2,"POU domain, class 4, transcription factor 2",intracellular|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|MAPK cascade|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|nervous system development|axonogenesis|axon guidance|sensory perception of sound|neuron differentiation|neuron differentiation|intracellular estrogen receptor signaling pathway|retinal ganglion cell axon guidance|retinal ganglion cell axon guidance|positive regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|axon extension|neuromuscular process controlling balance|retina development in camera-type eye|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.1,0.31,10,-0.3,0.668,-0.2,0.824,-0.824,0.64,0,0,-1.8,0.8
ENSMUSG00000022987,ZFP641,zinc finger protein 641,intracellular|nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.5,2.47,-0.3,0.812,-0.812,0.642,0,0,-1.7,0.9
ENSMUSG00000019261,MAP1S,microtubule-associated protein 1S,nucleus|nucleus|nucleolus|cytoplasm|cytosol|cytosol|cytoskeleton|microtubule|microtubule cytoskeleton|cell junction|dendrite|cell projection|neuronal cell body|synapse|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,microtubule cytoskeleton organization|microtubule bundle formation|microtubule bundle formation|apoptotic process|neuron projection morphogenesis|execution phase of apoptosis|execution phase of apoptosis|,DNA binding|DNA binding|microtubule binding|microtubule binding|tubulin binding|tubulin binding|identical protein binding|beta-tubulin binding|beta-tubulin binding|actin filament binding|,10,-0.4,2.8,10,0,0,-0.3,0.807,-0.807,0.643,0,0,-1.9,0.5
ENSMUSG00000016831,TOX4,TOX high mobility group box family member 4,chromatin|nucleus|PTW/PP1 phosphatase complex|,biological_process|,DNA binding|,10,0.3,1.2,10,0,0,0.2,0.804,0.804,0.644,0,0,-0.7,1.9
ENSMUSG00000044024,RELL2,RELT-like 2,basement membrane|plasma membrane|membrane|integral component of membrane|extracellular matrix|,positive regulation of cell-substrate adhesion|,collagen binding|,9,0.4,1.17,10,-0.2,0.263,-0.2,0.803,-0.803,0.644,0,0,-1.4,1.6
ENSMUSG00000038354,ANKRD35,ankyrin repeat domain 35,cellular_component|,biological_process|,molecular_function|,10,-0.3,2.38,10,1.1,1.67,-0.2,0.798,-0.798,0.645,0,0,-1,2
ENSMUSG00000024136,DNASE1L2,deoxyribonuclease 1-like 2,cellular_component|extracellular region|cytoplasm|,hair follicle development|corneocyte development|DNA catabolic process|DNA catabolic process|nucleic acid phosphodiester bond hydrolysis|,"nuclease activity|endonuclease activity|deoxyribonuclease activity|hydrolase activity|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|metal ion binding|",10,0.1,0.179,10,0.2,0.69,0.2,0.794,0.794,0.646,0,0,-1.4,1.4
ENSMUSG00000042448,HOXD1,homeobox D1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|sensory perception of pain|neuron differentiation|embryonic skeletal system development|",DNA binding|sequence-specific DNA binding|,10,0.2,0.35,10,-0.2,0.729,-0.2,0.782,-0.782,0.649,0,0,-1.5,1.2
ENSMUSG00000046667,RBM12B1,RNA binding motif protein 12 B1,cellular_component|,biological_process|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.3,0.249,10,0.6,2.02,0.5,0.777,0.777,0.65,0,0,-0.9,1.9
ENSMUSG00000025930,MSC,musculin,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|branchiomeric skeletal muscle development|palate development|diaphragm development|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|protein dimerization activity|,7,0.5,1.18,7,0.1,0.156,0.2,0.777,0.777,0.65,0,0,-1,2
ENSMUSG00000031256,CSTF2,"cleavage stimulation factor, 3' pre-RNA subunit 2",nucleus|mRNA cleavage and polyadenylation specificity factor complex|cleavage body|,mRNA processing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.1,0.088,10,0.4,1.36,0.2,0.776,0.776,0.65,0,0,-0.9,1.8
ENSMUSG00000036098,MYRF,myelin regulatory factor,nucleus|cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|proteolysis|oligodendrocyte development|central nervous system myelination|cell differentiation|positive regulation of myelination|central nervous system myelin maintenance|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|oligodendrocyte differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|sequence-specific DNA binding|,9,-0.2,0.218,9,-0.2,0.621,-0.2,0.771,-0.771,0.651,0,0,-1.8,1
ENSMUSG00000017007,RBPJL,recombination signal binding protein for immunoglobulin kappa J region-like,nucleus|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|,10,-0.2,0.709,10,0.4,2,0.3,0.769,0.769,0.651,0,0,-1.2,1.6
ENSMUSG00000039037,ST6GALNAC5,"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|glycosphingolipid biosynthetic process|oligosaccharide biosynthetic process|sialylation|,"alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity|sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,10,-0.2,1.75,-0.2,0.764,-0.764,0.652,0,0,-1.7,1.1
ENSMUSG00000035150,EIF2S3X,"eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked",extracellular vesicular exosome|,translation|translational initiation|,"nucleotide binding|translation initiation factor activity|GTPase activity|GTP binding|translation factor activity, nucleic acid binding|",7,-0.3,1.29,8,0.2,0.584,-0.4,0.76,-0.76,0.653,0,0,-1.9,1.3
ENSMUSG00000049878,RLF,rearranged L-myc fusion sequence,cellular_component|,DNA integration|chromosome organization|,molecular_function|,10,-0.4,0.796,10,-0.2,0.0212,-0.4,0.749,-0.749,0.655,0,0,-1.8,0.8
ENSMUSG00000013465,NELFB,negative elongation factor complex member B,nucleus|cytoplasm|NELF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",None,8,-0.2,0.655,8,-0.1,0.205,-0.2,0.747,-0.747,0.656,0,0,-1.4,1.6
ENSMUSG00000025997,IKZF2,IKAROS family zinc finger 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",nucleic acid binding|DNA binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,0,0,10,-0.5,1.15,-0.4,0.738,-0.738,0.658,0,0,-1.9,0.6
ENSMUSG00000018379,SRSF1,serine/arginine-rich splicing factor 1,nucleus|nucleus|nucleoplasm|spliceosomal complex|cytoplasm|nuclear speck|nuclear speck|exon-exon junction complex|extracellular vesicular exosome|catalytic step 2 spliceosome|,mRNA 5'-splice site recognition|in utero embryonic development|mRNA processing|transport|RNA splicing|RNA splicing|mRNA transport|cardiac muscle contraction|,nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|protein binding|poly(A) RNA binding|RS domain binding|,2,0.4,0.426,2,0.4,0.368,0.4,0.728,0.728,0.66,0,0,-1.6,2
ENSMUSG00000042596,TFAP2D,"transcription factor AP-2, delta",nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of neuron apoptotic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|inferior colliculus development|",RNA polymerase II regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,-0.2,0.618,10,-0.2,0.167,-0.2,0.721,-0.721,0.662,0,0,-1.8,0.9
ENSMUSG00000029404,ARL6IP4,ADP-ribosylation factor-like 6 interacting protein 4,nucleus|,mRNA processing|RNA splicing|,protein binding|poly(A) RNA binding|,10,0,0,10,-0.6,2.34,-0.5,0.711,-0.711,0.664,0,0,-1.8,0.9
ENSMUSG00000064043,TRERF1,transcriptional regulating factor 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|metal ion binding|,10,0,0,10,-0.3,1.21,-0.2,0.696,-0.696,0.667,0,0,-1.7,0.9
ENSMUSG00000035923,MYF6,myogenic factor 6,nucleus|,"somitogenesis|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|muscle organ development|skeletal muscle tissue development|skeletal muscle tissue development|skeletal muscle tissue development|cell differentiation|skeletal muscle cell differentiation|skeletal muscle tissue regeneration|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|muscle tissue morphogenesis|",DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein dimerization activity|,10,-0.2,0.341,10,-0.6,1.18,-0.4,0.694,-0.694,0.668,0,0,-1.5,1.8
ENSMUSG00000042408,ZMYM6,"zinc finger, MYM-type 6",cellular_component|,cytoskeleton organization|regulation of cell morphogenesis|,molecular_function|,10,0,0,10,0.2,0.973,0.2,0.683,0.683,0.67,0,0,-0.9,1.9
ENSMUSG00000055762,EEF1D,eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein),nucleus|nucleolus|cytoplasm|eukaryotic translation elongation factor 1 complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|translation|translational elongation|signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|",DNA binding|translation elongation factor activity|signal transducer activity|,10,0.2,0.169,10,0.2,0.575,0.2,0.683,0.683,0.67,0,0,-0.9,1.8
ENSMUSG00000038692,HOXB4,homeobox B4,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|morphogenesis of an epithelial sheet|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell proliferation|anterior/posterior pattern specification|hemopoiesis|positive regulation of transcription from RNA polymerase II promoter|somatic stem cell division|spleen development|bone marrow development|embryonic skeletal system morphogenesis|skeletal system morphogenesis|skeletal system morphogenesis|definitive hemopoiesis|hematopoietic stem cell differentiation|positive regulation of stem cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.7,1.94,10,-0.1,0.176,-0.2,0.673,-0.673,0.672,0,0,-2,0.6
ENSMUSG00000040661,RAD54L2,RAD54 like 2 (S. cerevisiae),nucleus|,regulation of RNA biosynthetic process|,nucleotide binding|DNA binding|transcription cofactor activity|helicase activity|ATP binding|hydrolase activity|protein kinase binding|,10,-0.3,0.194,10,-0.2,0.521,-0.2,0.652,-0.652,0.677,0,0,-1.8,0.9
ENSMUSG00000026004,KANSL1L,KAT8 regulatory NSL complex subunit 1-like,histone acetyltransferase complex|cellular_component|,biological_process|,molecular_function|,10,-0.1,0.14,10,-0.4,1.26,-0.2,0.652,-0.652,0.677,0,0,-1.7,1.1
ENSMUSG00000027799,NBEA,neurobeachin,intracellular|cell|trans-Golgi network|cytosol|plasma membrane|endomembrane system|membrane|cell junction|synapse|postsynaptic membrane|,protein targeting|post-Golgi vesicle-mediated transport|protein localization|,protein kinase binding|protein kinase A binding|,10,0,0,10,0.2,0.897,0.2,0.651,0.651,0.677,0,0,-1.3,1.6
ENSMUSG00000042377,FAM83G,"family with sequence similarity 83, member G",cellular_component|,biological_process|,molecular_function|,10,0.3,0.318,10,1.1,1.18,0.8,0.636,0.636,0.681,0,0,-0.5,2
ENSMUSG00000036932,AIFM1,"apoptosis-inducing factor, mitochondrion-associated 1",nucleus|nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|mitochondrion|mitochondrial outer membrane|mitochondrial inner membrane|mitochondrial intermembrane space|mitochondrial intermembrane space|cytosol|cytosol|membrane|,apoptotic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|response to oxidative stress|apoptotic mitochondrial changes|positive regulation of cell death|neuron differentiation|mitochondrial respiratory chain complex I assembly|positive regulation of apoptotic process|cell redox homeostasis|neuron apoptotic process|oxidation-reduction process|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of apoptotic DNA fragmentation|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|DNA binding|aldo-keto reductase (NADP) activity|electron-transferring-flavoprotein dehydrogenase activity|isocitrate dehydrogenase activity|mevaldate reductase activity|protein binding|gluconate dehydrogenase activity|NAD(P)H oxidase activity|steroid dehydrogenase activity|oxidoreductase activity|oxidoreductase activity, acting on NAD(P)H|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|protein dimerization activity|3-ketoglucose-reductase activity|flavin adenine dinucleotide binding|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|FAD binding|",10,-0.7,1.04,10,-0.1,0.213,-0.2,0.63,-0.63,0.682,0,0,-2,0.7
ENSMUSG00000041995,ZBED3,"zinc finger, BED domain containing 3",cytoplasm|cytosol|membrane|,negative regulation of protein phosphorylation|Wnt signaling pathway|positive regulation of transcription from RNA polymerase II promoter|protein stabilization|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,DNA binding|protein binding|metal ion binding|,10,-0.3,0.227,10,-0.2,0.527,-0.3,0.624,-0.624,0.684,0,0,-1.8,1
ENSMUSG00000061283,TGIF2LX1,"TGFB-induced factor homeobox 2-like, X-linked 1",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.728,-0.2,0.62,-0.62,0.685,0,0,-1.6,1.1
ENSMUSG00000025255,ZFHX4,zinc finger homeodomain 4,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0.2,0.319,10,0.1,0.371,0.2,0.619,0.619,0.685,0,0,-1.1,1.7
ENSMUSG00000006720,ZFP184,zinc finger protein 184 (Kruppel-like),intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.745,10,-0.1,0.0206,-0.2,0.606,-0.606,0.688,0,0,-1.7,1
ENSMUSG00000055067,SMYD3,SET and MYND domain containing 3,nucleus|cytoplasm|,nucleosome assembly|negative regulation of protein kinase activity|myotube cell development|chromatin modification|peptidyl-lysine methylation|methylation|positive regulation of peptidyl-serine phosphorylation|histone lysine methylation|establishment of protein localization|positive regulation of transcription from RNA polymerase II promoter|cellular response to dexamethasone stimulus|,RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core binding|RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding|protein binding|methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|metal ion binding|,10,0.1,0.193,9,0.2,0.502,0.1,0.594,0.594,0.691,0,0,-1.1,1.7
ENSMUSG00000055817,MTA3,metastasis associated 3,nucleus|nucleus|cytoplasm|cohesin complex|NuRD complex|intracellular membrane-bounded organelle|,"regulation of transcription, DNA-templated|positive regulation of cell proliferation|positive regulation of G2/M transition of mitotic cell cycle|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,9,-0.1,0.0932,10,-0.4,1.1,-0.1,0.587,-0.587,0.693,0,0,-1.7,1.1
ENSMUSG00000068823,CSDE1,"cold shock domain containing E1, RNA binding",cytoplasm|mitochondrial inner membrane|Golgi apparatus|plasma membrane|CRD-mediated mRNA stability complex|,"regulation of transcription, DNA-templated|nuclear-transcribed mRNA catabolic process, no-go decay|",nucleic acid binding|DNA binding|RNA binding|poly(A) RNA binding|,10,-0.3,0.851,10,0.6,2.98,0.5,0.585,0.585,0.693,0,0,-1.1,1.8
ENSMUSG00000006310,ZBTB32,zinc finger and BTB domain containing 32,nuclear chromosome|nucleus|,"regulation of cytokine production|transcription, DNA-templated|regulation of transcription, DNA-templated|hemopoiesis|T cell proliferation|regulation of RNA biosynthetic process|",nucleic acid binding|DNA binding|transcription corepressor activity|zinc ion binding|metal ion binding|,10,-0.1,0.0297,10,-0.2,0.671,-0.2,0.581,-0.581,0.694,0,0,-1.7,1
ENSMUSG00000003992,SSBP2,single-stranded DNA binding protein 2,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|single-stranded DNA binding|protein binding|,10,0.1,0.133,10,0.1,0.496,0.1,0.577,0.577,0.695,0,0,-1.2,1.6
ENSMUSG00000023980,TAF8,"TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorq",nucleus|transcription factor TFIID complex|cytoplasm|perinuclear region of cytoplasm|,"inner cell mass cell proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell differentiation|regulation of fat cell differentiation|positive regulation of transcription, DNA-templated|maintenance of protein location in nucleus|",protein heterodimerization activity|,10,0.5,0.257,10,-0.3,2.25,-0.2,0.577,-0.577,0.695,0,0,-0.8,2
ENSMUSG00000060206,ZFP462,zinc finger protein 462,nucleus|,chromatin organization|negative regulation of DNA binding|positive regulation of transcription from RNA polymerase II promoter|,molecular_function|,10,0.3,0.677,10,1.9,2.09,0.1,0.574,0.574,0.696,0,0,-0.7,3
ENSMUSG00000050240,HIC2,hypermethylated in cancer 2,nucleus|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|protein C-terminus binding|metal ion binding|,10,-0.4,1.06,10,0,0,-0.3,0.562,-0.562,0.699,0,0,-1.9,0.8
ENSMUSG00000042895,ABRA,actin-binding Rho activating protein,cytoplasm|cytoskeleton|plasma membrane|actin cytoskeleton|myofibril|sarcomere|,"protein import into nucleus, translocation|transcription, DNA-templated|regulation of transcription, DNA-templated|transport|protein transport|positive regulation of Rho protein signal transduction|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of sequence-specific DNA binding transcription factor activity|",transcription coactivator activity|actin binding|,9,0,0,9,-0.3,1.33,-0.2,0.559,-0.559,0.7,0,0,-1.8,1
ENSMUSG00000023971,RRP36,ribosomal RNA processing 36 homolog (S. cerevisiae),nucleus|nucleolus|,rRNA processing|ribosome biogenesis|ribosomal small subunit biogenesis|,poly(A) RNA binding|,10,0,0,10,0.4,1.8,-0.3,0.545,-0.545,0.703,0,0,-1.5,1.3
ENSMUSG00000028940,HES2,hairy and enhancer of split 2 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|double-stranded DNA binding|transcription factor binding|protein dimerization activity|,10,0,0,10,0.6,1.41,0.2,0.537,0.537,0.705,0,0,-0.4,2
ENSMUSG00000040446,RPRD1A,regulation of nuclear pre-mRNA domain containing 1A,"DNA-directed RNA polymerase II, holoenzyme|",dephosphorylation of RNA polymerase II C-terminal domain|,molecular_function|,10,-0.8,1.83,10,0.3,0.807,0.2,0.529,0.529,0.707,0,0,-2,1
ENSMUSG00000028580,PUM1,pumilio RNA-binding family member 1,cytoplasm|,regulation of translation|,RNA binding|poly(A) RNA binding|,10,-0.3,0.335,10,-0.1,0.388,-0.2,0.529,-0.529,0.707,0,0,-1.7,1
ENSMUSG00000061143,MAML3,mastermind like 3 (Drosophila),nucleus|nucleus|,Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|,transcription coactivator activity|transcription coactivator activity|,10,0.2,0.563,10,-0.2,0.878,0.2,0.521,0.521,0.71,0,0,-1.2,1.5
ENSMUSG00000048540,NHLH2,nescient helix loop helix 2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|mating behavior|cell differentiation|ovulation cycle|",RNA polymerase II activating transcription factor binding|DNA binding|protein binding|protein dimerization activity|,10,-0.6,2.15,10,0.2,0.598,0.2,0.512,0.512,0.712,0,0,-1.8,1.1
ENSMUSG00000058028,ZSCAN5B,zinc finger and SCAN domain containing 5B,nucleus|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|,sequence-specific DNA binding RNA polymerase II transcription factor activity|metal ion binding|,10,0,0,10,-0.4,1.75,-0.3,0.511,-0.511,0.712,0,0,-1.2,1.8
ENSMUSG00000000056,NARF,nuclear prelamin A recognition factor,nucleus|lamin filament|nuclear lumen|,biological_process|,lamin binding|,10,0.9,1.02,10,-0.1,0.156,0.9,0.509,0.509,0.713,0,0,-1,2
ENSMUSG00000056476,MED12L,mediator complex subunit 12-like,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|biological_process|",RNA polymerase II transcription cofactor activity|beta-catenin binding|transcription factor binding|,10,-0.2,0.503,10,-0.1,0.072,-0.2,0.509,-0.509,0.713,0,0,-1.6,1.2
ENSMUSG00000078796,ZFP541,zinc finger protein 541,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|biological_process|cell differentiation|",nucleic acid binding|DNA binding|chromatin binding|metal ion binding|,10,0.5,1.95,10,0,0,0.3,0.506,0.506,0.714,0,0,-0.8,1.9
ENSMUSG00000044876,ZFP444,zinc finger protein 444,nucleus|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|,sequence-specific DNA binding RNA polymerase II transcription factor activity|metal ion binding|,10,-0.1,0.0989,10,-0.2,0.492,-0.1,0.496,-0.496,0.716,0,0,-1.7,1.2
ENSMUSG00000028842,AGO3,argonaute RISC catalytic subunit 3,cytoplasm|membrane|ribonucleoprotein complex|micro-ribonucleoprotein complex|,mRNA catabolic process|regulation of translation|gene silencing by RNA|negative regulation of translation involved in gene silencing by miRNA|regulation of stem cell proliferation|,nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.9,0.96,10,-0.1,0.126,0.3,0.496,0.496,0.716,0,0,-0.7,2
ENSMUSG00000048280,ZFP738,zinc finger protein 738,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.203,10,-0.4,1.33,-0.1,0.494,-0.494,0.717,0,0,-2,0.9
ENSMUSG00000031365,ZFP275,zinc finger protein 275,None,None,metal ion binding|,10,0.2,0.445,10,1,1.01,0.2,0.484,0.484,0.72,0,0,-0.4,2
ENSMUSG00000053646,PLXNB1,plexin B1,semaphorin receptor complex|intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,negative regulation of cell adhesion|signal transduction|multicellular organismal development|regulation of cell shape|regulation of cell shape|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of Rho GTPase activity|negative regulation of osteoblast proliferation|ossification involved in bone maturation|neuron projection morphogenesis|positive regulation of axonogenesis|regulation of cytoskeleton organization|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway|semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis|,receptor activity|protein binding|semaphorin receptor activity|semaphorin receptor activity|GTPase activating protein binding|,10,0,0,10,0.2,0.921,0.2,0.483,0.483,0.72,0,0,-1.7,1.2
ENSMUSG00000092260,ZFP963,zinc finger protein 963,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,6,0.4,0.938,6,-0.1,0.266,-0.2,0.483,-0.483,0.72,0,0,-1.8,1.4
ENSMUSG00000024968,RCOR2,REST corepressor 2,chromatin|nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|,10,-0.3,0.497,10,-0.1,0.235,-0.2,0.482,-0.482,0.72,0,0,-1.7,1.1
ENSMUSG00000031907,ZFP90,zinc finger protein 90,intracellular|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of DNA binding|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,-0.3,1.54,10,0,0,-0.3,0.482,-0.482,0.72,0,0,-1.9,0.8
ENSMUSG00000008489,ELAVL2,"ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)",None,None,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.1,0.359,10,-0.1,0.163,-0.1,0.477,-0.477,0.722,0,0,-1.5,1.4
ENSMUSG00000015937,H2AFY,"H2A histone family, member Y",nucleosome|nuclear chromatin|condensed chromosome|Barr body|nucleus|nucleus|chromosome|nucleolus|centrosome|ESC/E(Z) complex|extracellular vesicular exosome|,"negative regulation of transcription from RNA polymerase II promoter|nucleosome assembly|dosage compensation|chromatin modification|negative regulation of histone phosphorylation|negative regulation of gene expression, epigenetic|establishment of protein localization to chromatin|negative regulation of protein serine/threonine kinase activity|negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|negative regulation of cell cycle G2/M phase transition|",rDNA binding|DNA binding|chromatin binding|double-stranded methylated DNA binding|protein kinase binding|protein serine/threonine kinase inhibitor activity|chromatin DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0.3,0.676,10,-0.3,0.879,-0.2,0.475,-0.475,0.722,0,0,-1.6,1.2
ENSMUSG00000040489,SOX30,SRY (sex determining region Y)-box 30,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding|,10,-0.2,0.59,10,0.3,0.785,-0.1,0.468,-0.468,0.724,0,0,-1.7,1.2
ENSMUSG00000008393,CARHSP1,calcium regulated heat stable protein 1,cytoplasmic exosome (RNase complex)|cytoplasm|cytosol|P granule|extracellular vesicular exosome|,"regulation of transcription, DNA-templated|regulation of mRNA stability|",nucleic acid binding|DNA binding|RNA binding|mRNA 3'-UTR binding|protein binding|,10,-0.1,0.259,10,-0.1,0.251,-0.1,0.466,-0.466,0.725,0,0,-2,0.7
ENSMUSG00000044186,NKX2-6,NK2 homeobox 6,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|heart development|positive regulation of cell proliferation|cell differentiation|embryonic heart tube development|negative regulation of apoptotic process|pharyngeal system development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,9,-0.3,0.449,9,-0.1,0.172,-0.3,0.466,-0.466,0.725,0,0,-1.8,1.1
ENSMUSG00000034429,ZFP707,zinc finger protein 707,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,-0.6,1.39,-0.4,0.465,-0.465,0.725,0,0,-1.9,0.8
ENSMUSG00000034949,ZFR2,zinc finger RNA binding protein 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,1.13,-0.2,0.465,-0.465,0.725,0,0,-1.1,1.7
ENSMUSG00000055116,ARNTL,aryl hydrocarbon receptor nuclear translocator-like,nucleus|nucleus|transcription factor complex|transcription factor complex|cytoplasm|nuclear body|chromatoid body|,"protein import into nucleus, translocation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|signal transduction|spermatogenesis|circadian rhythm|circadian rhythm|negative regulation of TOR signaling|circadian regulation of gene expression|circadian regulation of gene expression|circadian regulation of gene expression|regulation of protein catabolic process|regulation of hair cycle|positive regulation of circadian rhythm|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of fat cell differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|regulation of neurogenesis|regulation of insulin secretion|regulation of cell cycle|response to redox state|response to redox state|positive regulation of canonical Wnt signaling pathway|oxidative stress-induced premature senescence|regulation of type B pancreatic cell development|negative regulation of glucocorticoid receptor signaling pathway|regulation of cellular senescence|positive regulation of skeletal muscle cell differentiation|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|core promoter sequence-specific DNA binding|core promoter binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|signal transducer activity|protein binding|transcription factor binding|aryl hydrocarbon receptor binding|bHLH transcription factor binding|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|Hsp90 protein binding|E-box binding|E-box binding|,10,0.2,0.639,10,0,0,0.1,0.463,0.463,0.725,0,0,-1.5,1.4
ENSMUSG00000022199,SLC22A17,"solute carrier family 22 (organic cation transporter), member 17",vacuole|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|integral component of organelle membrane|,transport|ion transport|signal transduction|siderophore transport|iron ion homeostasis|transmembrane transport|,transmembrane signaling receptor activity|transporter activity|protein binding|transmembrane transporter activity|,10,-0.3,0.225,10,-0.2,0.291,-0.3,0.462,-0.462,0.726,0,0,-1.8,0.9
ENSMUSG00000016624,PHF21B,PHD finger protein 21B,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.3,0.535,10,1,0.91,0.2,0.46,0.46,0.726,0,0,-0.5,2
ENSMUSG00000043639,RBM20,RNA binding motif protein 20,nucleus|,mRNA processing|heart development|RNA splicing|positive regulation of RNA splicing|positive regulation of RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|zinc ion binding|,10,0,0,10,0.4,0.882,0.3,0.455,0.455,0.728,0,0,-0.7,1.9
ENSMUSG00000074397,FOXR1,forkhead box R1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.2,1.09,10,0,0,-0.1,0.453,-0.453,0.728,0,0,-1.2,1.8
ENSMUSG00000033961,ZFP446,zinc finger protein 446,extracellular space|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|metal ion binding|,10,-0.3,1.17,10,0.1,0.106,-0.3,0.451,-0.451,0.729,0,0,-1.7,1.2
ENSMUSG00000060284,SP7,Sp7 transcription factor 7,nucleus|nucleus|cytoplasm|,"osteoblast differentiation|osteoblast differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|hematopoietic stem cell differentiation|positive regulation of stem cell differentiation|",nucleic acid binding|DNA binding|DNA binding|protein binding|DEAD/H-box RNA helicase binding|metal ion binding|,10,0,0,10,-0.4,0.98,-0.3,0.443,-0.443,0.731,0,0,-1.9,0.8
ENSMUSG00000055150,ZFP78,zinc finger protein 78,nucleus|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.215,10,-0.1,0.27,-0.1,0.443,-0.443,0.731,0,0,-1.5,1.3
ENSMUSG00000025200,CWF19L1,"CWF19-like 1, cell cycle control (S. pombe)",cellular_component|,biological_process|,catalytic activity|,10,0.2,1.17,10,-0.1,0.175,0.2,0.442,0.442,0.731,0,0,-1.7,1.3
ENSMUSG00000042500,AGO4,argonaute RISC catalytic subunit 4,cytoplasmic mRNA processing body|cytoplasm|membrane|ribonucleoprotein complex|micro-ribonucleoprotein complex|,mRNA catabolic process|regulation of translation|gene silencing by RNA|negative regulation of translation involved in gene silencing by miRNA|,nucleic acid binding|RNA binding|,10,0,0,10,-0.5,2.05,-0.1,0.442,-0.442,0.731,0,0,-2,0.9
ENSMUSG00000021621,ZCCHC9,"zinc finger, CCHC domain containing 9",cellular_component|,negative regulation of phosphatase activity|,nucleic acid binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.1,0.202,10,-0.1,0.274,-0.1,0.435,-0.435,0.734,0,0,-1.7,1.1
ENSMUSG00000041124,MSANTD4,Myb/SANT-like DNA-binding domain containing 4 with coiled-coils,nucleus|,biological_process|,molecular_function|,10,0.5,0.525,10,-0.1,0.103,-0.1,0.432,-0.432,0.734,0,0,-1.4,1.5
ENSMUSG00000047002,MSGN1,mesogenin 1,nucleus|,"somitogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|segment specification|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|chromatin binding|protein dimerization activity|,10,0.1,0.389,10,0.1,0.0782,0.1,0.428,0.428,0.736,0,0,-0.9,1.8
ENSMUSG00000029235,PDCL2,phosducin-like 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,1.2,2.02,-0.2,0.427,-0.427,0.736,0,0,-1,2
ENSMUSG00000036279,ZBTB20,zinc finger and BTB domain containing 20,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|metal ion binding|,7,0,0,7,-0.7,1.31,-0.3,0.427,-0.427,0.736,0,0,-2,1
ENSMUSG00000058669,NKX2-9,NK2 homeobox 9,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|axonogenesis|respiratory tube development|lung development|negative regulation of epithelial cell proliferation|",DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0.1,0.239,10,-0.2,0.503,-0.1,0.425,-0.425,0.737,0,0,-1.9,0.8
ENSMUSG00000073894,RBMXL2,"RNA binding motif protein, X-linked-like 2",None,biological_process|,molecular_function|,10,-0.1,0.00408,10,0.3,0.919,0.1,0.418,0.418,0.739,0,0,-1,1.7
ENSMUSG00000026987,BAZ2B,"bromodomain adjacent to zinc finger domain, 2B",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.081,10,0.2,0.484,0.1,0.416,0.416,0.739,0,0,-1.3,1.5
ENSMUSG00000065999,GM13154,predicted gene 13154,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.0182,10,-0.2,0.566,-0.1,0.416,-0.416,0.739,0,0,-1.5,1.4
ENSMUSG00000005417,MPRIP,myosin phosphatase Rho interacting protein,cytoplasm|cytoskeleton|actin cytoskeleton|,None,actin binding|,10,0,0,10,-0.1,0.713,-0.1,0.413,-0.413,0.74,0,0,-2,0.7
ENSMUSG00000040209,ZFP704,zinc finger protein 704,None,None,metal ion binding|,10,-0.2,0.584,10,0,0,-0.1,0.411,-0.411,0.74,0,0,-1.6,1.3
ENSMUSG00000054199,GON4L,gon-4-like (C.elegans),nucleus|,"regulation of transcription, DNA-templated|B cell differentiation|",molecular_function|DNA binding|chromatin binding|,10,0.1,0.077,10,0.2,0.455,0.1,0.409,0.409,0.741,0,0,-1,1.8
ENSMUSG00000063382,BCL9L,B cell CLL/lymphoma 9-like,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of epithelial to mesenchymal transition|regulation of cell morphogenesis|negative regulation of transforming growth factor beta receptor signaling pathway|somatic stem cell maintenance|skeletal muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|canonical Wnt signaling pathway|",beta-catenin binding|beta-catenin binding|,10,-0.2,0.496,10,-0.1,0.0743,-0.1,0.403,-0.403,0.742,0,0,-1.1,1.8
ENSMUSG00000057967,FGF18,fibroblast growth factor 18,extracellular region|nucleolus|,ossification|angiogenesis|intramembranous ossification|endochondral ossification|chondrocyte development|signal transduction|nervous system development|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|lung development|positive regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of chondrocyte differentiation|positive regulation of ERK1 and ERK2 cascade|,receptor binding|fibroblast growth factor receptor binding|type 1 fibroblast growth factor receptor binding|type 2 fibroblast growth factor receptor binding|growth factor activity|,10,0.3,1.13,10,0,0,0.1,0.4,0.4,0.743,0,0,-0.9,1.8
ENSMUSG00000003410,ELAVL3,"ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)",None,multicellular organismal development|nervous system development|cell differentiation|,nucleotide binding|nucleic acid binding|RNA binding|AU-rich element binding|AU-rich element binding|,10,-0.3,1.1,10,0.2,0.147,-0.1,0.399,-0.399,0.744,0,0,-1.3,1.5
ENSMUSG00000025086,TRUB1,TruB pseudouridine (psi) synthase homolog 1 (E. coli),cellular_component|,pseudouridine synthesis|RNA processing|tRNA processing|RNA modification|,RNA binding|pseudouridine synthase activity|isomerase activity|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|baruol synthase activity|,9,-0.1,0.16,9,-0.2,0.354,-0.2,0.395,-0.395,0.745,0,0,-1.5,1.5
ENSMUSG00000066009,GM13051,predicted gene 13051,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,3,0,0,3,-0.2,0.537,-0.2,0.395,-0.395,0.745,0,0,-2,1.5
ENSMUSG00000075040,ZFP408,zinc finger protein 408,cellular_component|,biological_process|,identical protein binding|,10,-0.4,1.2,10,-0.1,0.0968,-0.1,0.394,-0.394,0.745,0,0,-1.8,1.3
ENSMUSG00000036775,DECR2,"2-4-dienoyl-Coenzyme A reductase 2, peroxisomal",peroxisome|peroxisomal membrane|,lipid metabolic process|fatty acid metabolic process|unsaturated fatty acid biosynthetic process|unsaturated fatty acid biosynthetic process|oxidation-reduction process|,"receptor binding|2,4-dienoyl-CoA reductase (NADPH) activity|2,4-dienoyl-CoA reductase (NADPH) activity|oxidoreductase activity|trans-2-enoyl-CoA reductase (NADPH) activity|",10,0.1,0.176,10,0.5,0.622,0.1,0.394,0.394,0.745,0,0,-1.2,1.7
ENSMUSG00000021012,ZC3H14,zinc finger CCCH type containing 14,nucleus|cytoplasm|,biological_process|,RNA binding|poly(A) RNA binding|metal ion binding|,10,0.4,1.39,10,-0.2,0.61,0.1,0.393,0.393,0.745,0,0,-1.2,1.6
ENSMUSG00000031403,DKC1,"dyskeratosis congenita 1, dyskerin",nucleus|nucleoplasm|telomerase holoenzyme complex|nucleolus|nucleolus|nucleolus|small nucleolar ribonucleoprotein complex|Cajal body|ribonucleoprotein complex|,rRNA modification|rRNA modification|pseudouridine synthesis|RNA-dependent DNA replication|rRNA processing|RNA processing|cell proliferation|RNA modification|ribosome biogenesis|DNA biosynthetic process|,telomerase activity|RNA binding|pseudouridylate synthase activity|pseudouridine synthase activity|isomerase activity|snoRNP binding|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|poly(A) RNA binding|baruol synthase activity|,4,0.4,0.931,4,-0.1,0.118,0.2,0.392,0.392,0.746,0,0,-1.4,2
ENSMUSG00000050954,ZFP169,zinc finger protein 169,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.4,0.304,10,0.1,0.179,0.2,0.382,0.382,0.749,0,0,-1.1,1.7
ENSMUSG00000021514,ZFP369,zinc finger protein 369,intracellular|nucleus|nucleus|cytoplasm|centrosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|apoptotic process|regulation of cell cycle|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|neurotrophin p75 receptor binding|protein binding|sequence-specific DNA binding|metal ion binding|,10,0.2,0.183,10,-0.3,0.284,0.2,0.377,0.377,0.75,0,0,-1.1,1.7
ENSMUSG00000027667,ZFP639,zinc finger protein 639,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell growth|negative regulation by host of viral transcription|positive regulation by host of viral transcription|negative regulation of transcription, DNA-templated|viral entry into host cell|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein self-association|transcription regulatory region DNA binding|metal ion binding|,10,-0.3,1.39,10,0.2,0.51,-0.1,0.376,-0.376,0.751,0,0,-1.7,1.1
ENSMUSG00000020366,MAPK9,mitogen-activated protein kinase 9,nucleus|nucleus|cytoplasm|mitochondrion|mitochondrion|cytosol|cytosol|,"release of cytochrome c from mitochondria|positive regulation of protein phosphorylation|protein phosphorylation|activation of cysteine-type endopeptidase activity involved in apoptotic process|JNK cascade|JNK cascade|JUN phosphorylation|JUN phosphorylation|positive regulation of gene expression|positive regulation of macrophage derived foam cell differentiation|positive regulation of cell morphogenesis involved in differentiation|phosphorylation|neuron projection development|positive regulation of prostaglandin biosynthetic process|regulation of protein ubiquitination|positive regulation of prostaglandin secretion|positive regulation of chemokine production|cellular response to UV|response to drug|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of nitric oxide biosynthetic process|positive regulation of transcription, DNA-templated|regulation of JNK cascade|response to cadmium ion|positive regulation of nitric-oxide synthase biosynthetic process|positive regulation of apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|JUN kinase activity|JUN kinase activity|MAP kinase activity|protein binding|ATP binding|transcription factor binding|cysteine-type endopeptidase activator activity involved in apoptotic process|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|mitogen-activated protein kinase kinase kinase binding|",10,-0.3,1.31,10,0.3,0.818,-0.2,0.365,-0.365,0.754,0,0,-1.5,1.3
ENSMUSG00000025592,DACH2,dachshund 2 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|development of primary female sexual characteristics|",DNA binding|,10,0,0,10,-0.7,2.31,-0.1,0.354,-0.354,0.757,0,0,-2,0.8
ENSMUSG00000033732,SF3B3,"splicing factor 3b, subunit 3",nucleus|spliceosomal complex|U12-type spliceosomal complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,molecular_function|nucleic acid binding|,6,0,0,6,0.3,0.727,0.2,0.337,0.337,0.763,0,0,-1.2,2
ENSMUSG00000029517,ANKRD7,ankyrin repeat domain 7,nucleus|,biological_process|,molecular_function|,10,-0.1,0.0165,10,1.2,1.38,-0.1,0.335,-0.335,0.764,0,0,-0.8,2
ENSMUSG00000037784,DZIP1L,DAZ interacting protein 1-like,centriole|ciliary basal body|,cilium assembly|,metal ion binding|,10,0,0,10,0.3,2,0.2,0.335,0.335,0.764,0,0,-1.3,1.5
ENSMUSG00000029178,KLF3,Kruppel-like factor 3 (basic),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,0.4,1.42,10,-0.1,0.377,-0.1,0.332,-0.332,0.765,0,0,-0.8,2
ENSMUSG00000041649,KLF8,Kruppel-like factor 8,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.3,1.06,10,0.1,0.00773,0.1,0.331,0.331,0.765,0,0,-1.7,1.2
ENSMUSG00000069227,GPRIN1,G protein-regulated inducer of neurite outgrowth 1,plasma membrane|membrane|cell projection|,neuron projection development|,phosphoprotein binding|,10,0.1,0.0378,10,0.2,0.408,0.1,0.324,0.324,0.767,0,0,-1,1.9
ENSMUSG00000040713,CREG1,cellular repressor of E1A-stimulated genes 1,extracellular region|transcription factor complex|extracellular vesicular exosome|,"regulation of transcription, DNA-templated|regulation of growth|oxidation-reduction process|",transcription factor binding|FMN binding|oxidoreductase activity|,10,0.2,0.866,10,-0.6,0.793,0.2,0.312,0.312,0.771,0,0,-1.8,1.1
ENSMUSG00000034839,LARP6,"La ribonucleoprotein domain family, member 6",nucleus|cytoplasm|ribonucleoprotein complex|,RNA processing|regulation of translation|,nucleotide binding|RNA binding|,10,0,0,10,0.7,1.28,0.5,0.31,0.31,0.772,0,0,-1,1.9
ENSMUSG00000064288,HIST1H4K,"histone cluster 1, H4k",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,9,0,0,9,0.4,0.762,0.2,0.31,0.31,0.772,0,0,-0.7,2
ENSMUSG00000028840,ZFP593,zinc finger protein 593,nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0.1,0.153,10,0.1,0.179,0.1,0.303,0.303,0.775,0,0,-1.5,1.5
ENSMUSG00000034522,ZFP395,zinc finger protein 395,nucleus|cytoplasm|,regulation of transcription from RNA polymerase II promoter|,DNA binding|,10,-0.2,0.0592,10,0.3,1.1,0.1,0.297,0.297,0.777,0,0,-1.4,1.4
ENSMUSG00000043668,TOX3,TOX high mobility group box family member 3,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|calcium-mediated signaling|negative regulation of neuron apoptotic process|positive regulation of transcription, DNA-templated|",DNA binding|chromatin binding|estrogen response element binding|protein homodimerization activity|phosphoprotein binding|,10,0,0,10,0.4,1.7,0.1,0.295,0.295,0.777,0,0,-1.3,1.5
ENSMUSG00000026466,TOR1AIP1,torsin A interacting protein 1,nucleus|nuclear envelope|nuclear envelope|nuclear envelope|membrane|integral component of membrane|,positive regulation of ATPase activity|protein localization to nucleus|nuclear membrane organization|nuclear membrane organization|,ATPase activator activity|protein binding|lamin binding|lamin binding|cytoskeletal protein binding|ATPase binding|,10,0.3,0.434,10,-0.1,0.309,-0.1,0.291,-0.291,0.779,0,0,-1.9,1.1
ENSMUSG00000031734,IRX3,Iroquois related homeobox 3,nucleus|cytoplasm|axon|,"kidney development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|mesoderm development|negative regulation of neuron differentiation|positive regulation of neuron differentiation|",DNA binding|sequence-specific DNA binding|,10,-0.1,0.0718,10,0.5,1.28,0.2,0.288,0.288,0.78,0,0,-1.2,1.8
ENSMUSG00000036819,JMJD4,jumonji domain containing 4,cellular_component|,biological_process|,molecular_function|,9,0.2,0.227,9,0.1,0.124,0.1,0.286,0.286,0.78,0,0,-1.2,1.7
ENSMUSG00000051034,ZFP11,zinc finger protein 11,nucleus|,"regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0.6,2.48,0.5,0.286,0.286,0.78,0,0,-0.8,1.9
ENSMUSG00000034384,BARHL2,BarH-like 2 (Drosophila),nucleus|nucleus|cytoplasm|,"cell fate determination|neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|neuron differentiation|neuron differentiation|regulation of axon extension|cell fate commitment|positive regulation of translation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,-0.4,1.97,-0.3,0.285,-0.285,0.781,0,0,-1.8,1
ENSMUSG00000042812,FOXF1,forkhead box F1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|blood vessel development|vasculogenesis|in utero embryonic development|in utero embryonic development|somitogenesis|morphogenesis of a branching structure|positive regulation of mesenchymal cell proliferation|endocardial cushion development|cardiac left ventricle morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|smoothened signaling pathway|determination of left/right symmetry|midgut development|mesoderm development|mesoderm development|heart development|organ morphogenesis|positive regulation of cell-substrate adhesion|detection of wounding|single organismal cell-cell adhesion|extracellular matrix organization|respiratory tube development|lung development|lung development|positive regulation of cell migration|pancreas development|negative regulation of mast cell degranulation|establishment of epithelial cell apical/basal polarity|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|lung alveolus development|lateral mesodermal cell differentiation|embryonic digestive tract morphogenesis|digestive tract development|embryonic digestive tract development|embryonic ectodermal digestive tract morphogenesis|embryonic foregut morphogenesis|negative regulation of inflammatory response|smooth muscle cell differentiation|regulation of smooth muscle cell differentiation|regulation of smooth muscle cell differentiation|lung morphogenesis|lung vasculature development|trachea development|epithelial tube branching involved in lung morphogenesis|branching involved in open tracheal system development|right lung morphogenesis|lung lobe morphogenesis|venous blood vessel development|epithelial cell differentiation involved in mammary gland alveolus development|cellular response to cytokine stimulus|cellular response to organic cyclic compound|renal system development|ureter development|mesenchyme migration|ductus arteriosus closure|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,0,0,10,-0.3,1.01,-0.1,0.284,-0.284,0.781,0,0,-1.7,1.2
ENSMUSG00000044676,ZFP612,zinc finger protein 612,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.5,0.934,10,0.3,1.51,-0.1,0.277,-0.277,0.784,0,0,-1.7,1.2
ENSMUSG00000034486,GBX2,gastrulation brain homeobox 2,nucleus|,"patterning of blood vessels|patterning of blood vessels|neural crest cell migration|transcription, DNA-templated|regulation of transcription, DNA-templated|axon guidance|cell proliferation|cerebellum development|midbrain-hindbrain boundary morphogenesis|rhombomere 2 development|thalamus development|forebrain neuron development|cerebellar granule cell precursor proliferation|hindbrain development|midbrain-hindbrain boundary development|tube morphogenesis|inner ear morphogenesis|autonomic nervous system development|",DNA binding|sequence-specific DNA binding|,10,-0.3,0.0806,10,0.1,0.345,0.1,0.275,0.275,0.784,0,0,-1.5,1.5
ENSMUSG00000003051,ELF3,E74-like factor 3,nucleus|nucleus|cytoplasm|,"blastocyst development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|inflammatory response|multicellular organismal development|anatomical structure morphogenesis|embryo development|cell differentiation|extracellular matrix organization|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|mammary gland involution|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|sequence-specific DNA binding|,10,0,0,10,-0.2,0.419,-0.2,0.272,-0.272,0.785,0,0,-1.8,1
ENSMUSG00000020623,MAP2K6,mitogen-activated protein kinase kinase 6,intracellular|nucleus|cytoplasm|cytoskeleton|,"MAPK cascade|MAPK cascade|activation of MAPK activity|activation of MAPK activity|activation of MAPK activity|positive regulation of protein phosphorylation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|protein phosphorylation|apoptotic process|response to stress|phosphorylation|positive regulation of prostaglandin secretion|positive regulation of apoptotic process|positive regulation of nitric-oxide synthase biosynthetic process|cardiac muscle contraction|","nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase activity|protein tyrosine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|",10,0,0,10,-0.4,0.655,0.1,0.258,0.258,0.79,0,0,-1.7,1.1
ENSMUSG00000051550,ZFP579,zinc finger protein 579,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,-0.2,0.686,-0.1,0.258,-0.258,0.79,0,0,-1.2,1.8
ENSMUSG00000000938,HOXA10,homeobox A10,nucleus|transcription factor complex|cytoplasm|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|spermatogenesis|single fertilization|male gonad development|anterior/posterior pattern specification|proximal/distal pattern formation|regulation of gene expression|embryonic limb morphogenesis|positive regulation of transcription from RNA polymerase II promoter|uterus development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|histone deacetylase binding|sequence-specific DNA binding|,10,0,0,10,-0.1,0.3,-0.1,0.249,-0.249,0.793,0,0,-1.8,1.1
ENSMUSG00000022464,SLC38A4,"solute carrier family 38, member 4",plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|ion transport|sodium ion transport|amino acid transport|,amino acid transmembrane transporter activity|symporter activity|,10,-0.3,0.282,10,0.4,1.16,0.3,0.249,0.249,0.793,0,0,-1.1,1.8
ENSMUSG00000024747,ALDH1A7,"aldehyde dehydrogenase family 1, subfamily A7",cytoplasm|,metabolic process|oxidation-reduction process|,"aldehyde dehydrogenase (NAD) activity|oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|",10,0.1,0.0251,10,0.2,0.275,0.1,0.246,0.246,0.794,0,0,-1.5,1.4
ENSMUSG00000021127,ZFP36L1,"zinc finger protein 36, C3H type-like 1",nucleus|cytoplasm|cytosol|,"nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|vasculogenesis|mRNA catabolic process|regulation of translation|T cell differentiation in thymus|regulation of mRNA stability|",DNA binding|mRNA binding|AU-rich element binding|poly(A) RNA binding|metal ion binding|,10,-0.3,0.279,10,0.1,0.229,0.1,0.246,0.246,0.794,0,0,-1.3,1.6
ENSMUSG00000020010,VNN3,vanin 3,extracellular space|plasma membrane|membrane|anchored component of membrane|,nitrogen compound metabolic process|pantothenate metabolic process|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|pantetheine hydrolase activity|",10,0.1,0.155,10,-0.4,0.641,-0.2,0.246,-0.246,0.794,0,0,-1.6,1.1
ENSMUSG00000024220,ZFP523,zinc finger protein 523,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,0,0,10,0.1,0.31,0.1,0.239,0.239,0.796,0,0,-0.8,2
ENSMUSG00000035951,ASCL3,achaete-scute complex homolog 3 (Drosophila),nucleus|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|",DNA binding|protein binding|protein dimerization activity|,10,0.1,0.0192,10,0.1,0.239,0.1,0.236,0.236,0.797,0,0,-1.7,1.2
ENSMUSG00000038902,POGZ,pogo transposable element with ZNF domain,nuclear chromatin|nucleus|chromosome|cytoplasm|,cell cycle|mitotic sister chromatid cohesion|cell division|kinetochore assembly|,nucleic acid binding|DNA binding|metal ion binding|,10,0.2,0.507,10,-0.1,0.153,0.1,0.235,0.235,0.798,0,0,-1.6,1.2
ENSMUSG00000003573,HOMER3,homer homolog 3 (Drosophila),cytoplasm|cytosol|plasma membrane|postsynaptic density|membrane|cell junction|basal part of cell|synapse|postsynaptic membrane|,G-protein coupled glutamate receptor signaling pathway|,protein binding|protein C-terminus binding|protein domain specific binding|,10,0.2,0.234,10,0.1,0.0729,0.1,0.226,0.226,0.801,0,0,-1.3,1.6
ENSMUSG00000034292,TRAF3IP1,TRAF3 interacting protein 1,intracellular|cell|cytoplasm|centrosome|cytosol|cytoskeleton|cilium|cilium|axoneme|microtubule cytoskeleton|intraciliary transport particle B|ciliary basal body|cell projection|,negative regulation of transcription from RNA polymerase II promoter|neural tube patterning|embryonic camera-type eye development|negative regulation of interferon-beta production|embryonic heart tube development|post-anal tail morphogenesis|intraciliary transport|intraciliary transport|cilium assembly|negative regulation of tyrosine phosphorylation of Stat6 protein|embryonic digit morphogenesis|negative regulation of defense response to virus|regulation of DNA binding|negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|,receptor binding|protein binding|microtubule binding|tubulin binding|,10,0.2,1.11,10,0,0,0.1,0.225,0.225,0.801,0,0,-1.6,1.4
ENSMUSG00000035529,PRDM4,PR domain containing 4,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cell growth|methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|DNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|death receptor binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.5,1.55,10,0,0,0.2,0.224,0.224,0.801,0,0,-1,1.7
ENSMUSG00000004540,PSG17,pregnancy specific glycoprotein 17,None,immune response|female pregnancy|,protein binding|heparan sulfate proteoglycan binding|,10,0.3,0.551,10,-1.1,0.539,0.1,0.223,0.223,0.802,0,0,-1.7,1.7
ENSMUSG00000094936,RBM4,RNA binding motif protein 4,cell|nucleus|nucleoplasm|nucleolus|cytoplasm|cytoplasmic stress granule|nuclear speck|,"regulation of alternative mRNA splicing, via spliceosome|regulation of alternative mRNA splicing, via spliceosome|cap-independent translational initiation|IRES-dependent translational initiation|regulation of gene expression|negative regulation of translation|pancreas development|negative regulation of translation in response to stress|circadian regulation of gene expression|negative regulation of translation involved in gene silencing by miRNA|insulin secretion involved in cellular response to glucose stimulus|enteroendocrine cell differentiation|glucose homeostasis|positive regulation of translation|negative regulation of translational initiation|regulation of insulin receptor signaling pathway|response to arsenic-containing substance|regulation of nucleocytoplasmic transport|positive regulation of muscle cell differentiation|stress-activated MAPK cascade|",RNA binding|mRNA binding|mRNA 3'-UTR binding|miRNA binding|poly(A) RNA binding|pre-mRNA intronic binding|pre-mRNA intronic pyrimidine-rich binding|,5,-0.6,1.9,5,0.1,0.141,-0.5,0.222,-0.222,0.802,0,0,-2,1.2
ENSMUSG00000037674,RFX7,"regulatory factor X, 7",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.121,10,-0.1,0.119,-0.1,0.219,-0.219,0.803,0,0,-1.7,1.2
ENSMUSG00000036916,ZFP280C,zinc finger protein 280C,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0.2,0.584,10,0,0,0.1,0.218,0.218,0.804,0,0,-1.3,1.6
ENSMUSG00000020519,SAP30L,SAP30-like,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|metal ion binding|,10,0.5,1.33,10,0,0,0.1,0.21,0.21,0.807,0,0,-0.9,1.8
ENSMUSG00000046574,PRR12,proline rich 12,cellular_component|,biological_process|,molecular_function|,10,0.1,0.232,10,0,0,0.1,0.207,0.207,0.808,0,0,-1.4,1.5
ENSMUSG00000040296,DDX58,DEAD (Asp-Glu-Ala-Asp) box polypeptide 58,cytoplasm|cytoskeleton|plasma membrane|tight junction|actin cytoskeleton|membrane|cell junction|ruffle membrane|cell projection|,positive regulation of defense response to virus by host|immune system process|detection of virus|response to virus|regulation of cell migration|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|positive regulation of interferon-beta production|RIG-I signaling pathway|positive regulation of transcription factor import into nucleus|response to exogenous dsRNA|innate immune response|innate immune response|positive regulation of transcription from RNA polymerase II promoter|defense response to virus|,"nucleotide binding|nucleic acid binding|double-stranded DNA binding|RNA binding|double-stranded RNA binding|double-stranded RNA binding|single-stranded RNA binding|single-stranded RNA binding|helicase activity|protein binding|ATP binding|zinc ion binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|identical protein binding|metal ion binding|",10,0,0,10,0.2,0.413,0.1,0.205,0.205,0.809,0,0,-1.6,1.3
ENSMUSG00000005267,ZFP287,zinc finger protein 287,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of cytokine biosynthetic process|positive regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.2,0.665,10,0,0,0.1,0.205,0.205,0.809,0,0,-1.2,1.7
ENSMUSG00000023034,NR4A1,"nuclear receptor subfamily 4, group A, member 1",nucleus|nucleus|transcription factor complex|cytoplasm|,"positive regulation of endothelial cell proliferation|cell migration involved in sprouting angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|apoptotic process|response to inorganic substance|endothelial cell chemotaxis|skeletal muscle cell differentiation|cellular response to vascular endothelial growth factor stimulus|positive regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|steroid hormone mediated signaling pathway|cellular response to fibroblast growth factor stimulus|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cellular response to organic substance|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|protein binding|zinc ion binding|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,-0.1,0.0427,10,-0.2,0.197,-0.2,0.193,-0.193,0.813,0,0,-1.7,1.1
ENSMUSG00000036158,PRICKLE1,prickle homolog 1 (Drosophila),nucleus|cytoplasm|cytosol|membrane|nuclear membrane|,"neural tube closure|protein import into nucleus|positive regulation of protein ubiquitination|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of transcription, DNA-templated|negative regulation of canonical Wnt signaling pathway|negative regulation of cardiac muscle cell myoblast differentiation|",protein binding|transcription factor binding|zinc ion binding|metal ion binding|,10,0,0,10,-0.1,0.406,-0.1,0.19,-0.19,0.814,0,0,-1.5,1.4
ENSMUSG00000048874,PHF3,PHD finger protein 3,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0.3,0.881,0.1,0.19,0.19,0.814,0,0,-1.3,1.6
ENSMUSG00000022053,EBF2,early B cell factor 2,nucleus|,"cell fate determination|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of chromatin binding|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|brown fat cell differentiation|adipose tissue development|",DNA binding|chromatin binding|protein binding|metal ion binding|protein dimerization activity|,10,-0.2,0.194,10,-0.1,0.0394,-0.2,0.188,-0.188,0.815,0,0,-1.9,0.8
ENSMUSG00000055407,MAP6,microtubule-associated protein 6,cytoplasm|Golgi apparatus|cytoskeleton|microtubule|perinuclear region of cytoplasm|,microtubule cytoskeleton organization|transport|lysosome localization|dendrite morphogenesis|,calmodulin binding|microtubule binding|,10,0.3,0.297,10,-0.1,0.268,0.2,0.187,0.187,0.815,0,0,-0.9,1.8
ENSMUSG00000000435,MYF5,myogenic factor 5,nucleus|,"cartilage condensation|ossification|somitogenesis|regulation of cell-matrix adhesion|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|muscle organ development|muscle organ development|skeletal muscle tissue development|skeletal muscle tissue development|cell differentiation|extracellular matrix organization|skeletal muscle cell differentiation|camera-type eye development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|muscle organ morphogenesis|embryonic skeletal system morphogenesis|muscle tissue morphogenesis|muscle tissue morphogenesis|",DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|protein dimerization activity|,10,0.3,1,10,-0.2,0.351,0.3,0.186,0.186,0.816,0,0,-1.3,1.5
ENSMUSG00000079466,PRDM12,PR domain containing 12,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|neurogenesis|methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|nucleic acid binding|DNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0.7,2.1,0.1,0.184,0.184,0.816,0,0,-0.6,2
ENSMUSG00000027238,FRMD5,FERM domain containing 5,cellular_component|cytoplasm|cytoskeleton|extrinsic component of membrane|,biological_process|,molecular_function|cytoskeletal protein binding|,10,-0.4,1.27,9,0.2,0.448,0.1,0.182,0.182,0.817,0,0,-1.7,1.3
ENSMUSG00000022286,GRHL2,grainyhead-like 2 (Drosophila),nucleus|,"in utero embryonic development|neural tube closure|cardiac ventricle morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|brain development|regulation of gene expression|neural tube development|respiratory tube development|multicellular organism growth|embryonic digit morphogenesis|camera-type eye development|embryonic organ development|embryonic cranial skeleton morphogenesis|face development|lung lobe morphogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|,10,0.2,0.751,10,-0.9,0.835,-0.1,0.181,-0.181,0.817,0,0,-2,0.9
ENSMUSG00000022394,L3MBTL2,l(3)mbt-like 2 (Drosophila),nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|chromatin modification|",zinc ion binding|methylated histone binding|histone binding|metal ion binding|,9,-0.3,1.26,10,0,0,-0.1,0.177,-0.177,0.819,0,0,-1.7,1.2
ENSMUSG00000052363,ZDHHC19,"zinc finger, DHHC domain containing 19",endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,"molecular_function|zinc ion binding|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.4,0.0329,10,0.2,0.29,0.2,0.177,0.177,0.819,0,0,-0.9,1.9
ENSMUSG00000011427,ZFP790,zinc finger protein 790,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.00838,10,0.1,0.181,0.1,0.173,0.173,0.82,0,0,-1.5,1.3
ENSMUSG00000034442,TRMT5,TRM5 tRNA methyltransferase 5,cellular_component|nucleus|cytoplasm|mitochondrion|,tRNA processing|biological_process|tRNA methylation|methylation|,molecular_function|methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|transferase activity|tRNA (guanine(37)-N(1))-methyltransferase activity|,9,0,0,9,-0.2,0.717,-0.1,0.173,-0.173,0.82,0,0,-1.6,1.4
ENSMUSG00000051451,CREBZF,CREB/ATF bZIP transcription factor,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|response to virus|negative regulation of transcription, DNA-templated|regulation of sequence-specific DNA binding transcription factor activity|",sequence-specific DNA binding transcription factor activity|protein binding|identical protein binding|sequence-specific DNA binding|,10,-0.2,0.895,10,0,0,-0.1,0.168,-0.168,0.822,0,0,-1.6,1.3
ENSMUSG00000042097,ZFP239,zinc finger protein 239,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,-0.4,1.13,-0.2,0.161,-0.161,0.825,0,0,-1.9,0.9
ENSMUSG00000004500,ZFP324,zinc finger protein 324,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,-0.2,0.586,-0.1,0.16,-0.16,0.825,0,0,-1.5,1.4
ENSMUSG00000050199,LGR4,leucine-rich repeat-containing G protein-coupled receptor 4,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,"osteoblast differentiation|immune system process|signal transduction|G-protein coupled receptor signaling pathway|multicellular organismal development|spermatogenesis|Wnt signaling pathway|cell differentiation|bone mineralization|male genitalia development|negative regulation of toll-like receptor signaling pathway|tube morphogenesis|innate immune response|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|bone remodeling|epithelial cell proliferation|negative regulation of cytokine secretion|canonical Wnt signaling pathway involved in metanephric kidney development|cell differentiation involved in metanephros development|metanephric glomerulus development|metanephric nephron tubule morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|",signal transducer activity|transmembrane signaling receptor activity|transmembrane signaling receptor activity|protein binding|protein-hormone receptor activity|,10,-0.2,0.219,10,-0.1,0.019,-0.1,0.159,-0.159,0.826,0,0,-1.8,1.1
ENSMUSG00000052135,FOXO6,forkhead box O6,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.3,1.06,10,0.2,0.462,-0.1,0.156,-0.156,0.827,0,0,-1.2,3.7
ENSMUSG00000032446,EOMES,eomesodermin homolog (Xenopus laevis),intracellular|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|endoderm formation|mesoderm formation|endodermal cell fate specification|blastocyst development|trophectodermal cell differentiation|trophectodermal cell differentiation|CD8-positive, alpha-beta T cell differentiation involved in immune response|CD8-positive, alpha-beta T cell differentiation involved in immune response|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|gastrulation|brain development|cardioblast differentiation|regulation of gene expression|stem cell maintenance|olfactory bulb development|cerebral cortex regionalization|cerebral cortex neuron differentiation|cell differentiation|interferon-gamma production|skeletal muscle cell differentiation|positive regulation of cell differentiation|positive regulation of cell differentiation|regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|regulation of neurogenesis|cell differentiation involved in embryonic placenta development|mesodermal to mesenchymal transition involved in gastrulation|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.4,1.33,10,0.2,0.586,0.1,0.156,0.156,0.827,0,0,-1.8,1.2
ENSMUSG00000032358,FAM83B,"family with sequence similarity 83, member B",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.125,10,-0.1,0.0446,-0.1,0.155,-0.155,0.827,0,0,-1.4,1.7
ENSMUSG00000028911,SRSF4,serine/arginine-rich splicing factor 4,nucleus|,"hematopoietic progenitor cell differentiation|mRNA processing|RNA splicing|negative regulation of mRNA splicing, via spliceosome|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.1,0.165,10,0.1,0.000502,0.1,0.151,0.151,0.829,0,0,-1.3,1.7
ENSMUSG00000032436,CMTM7,CKLF-like MARVEL transmembrane domain containing 7,extracellular space|membrane|membrane|integral component of membrane|,B-1a B cell differentiation|chemotaxis|,molecular_function|cytokine activity|,10,0.1,0.132,10,-0.3,1.15,-0.2,0.15,-0.15,0.829,0,0,-1.7,1.2
ENSMUSG00000046541,ZFP526,zinc finger protein 526,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.1,0.0288,10,-0.7,1.39,-0.1,0.147,-0.147,0.83,0,0,-1.9,0.9
ENSMUSG00000079681,ZGLP1,"zinc finger, GATA-like protein 1",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|oocyte development|",DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0.1,0.129,10,0.1,0.029,0.1,0.144,0.144,0.831,0,0,-1.8,1.2
ENSMUSG00000019338,ZFP687,zinc finger protein 687,nucleus|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0.3,0.602,10,0,0,0.1,0.144,0.144,0.831,0,0,-0.9,1.9
ENSMUSG00000078502,GM13212,predicted gene 13212,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,8,0,0,8,0.5,2.05,0.2,0.138,0.138,0.834,0,0,-1,1.9
ENSMUSG00000055200,SERTAD3,SERTA domain containing 3,nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of cell growth|positive regulation of transcription, DNA-templated|",protein binding|,10,0,0,10,-0.3,0.948,-0.1,0.137,-0.137,0.834,0,0,-1.9,0.8
ENSMUSG00000037533,RAPGEF6,Rap guanine nucleotide exchange factor (GEF) 6,plasma membrane|,positive regulation of GTPase activity|,guanyl-nucleotide exchange factor activity|Ras GTPase binding|GTP-dependent protein binding|,10,-0.3,1.01,10,0,0,-0.2,0.127,-0.127,0.838,0,0,-1.8,1
ENSMUSG00000024955,ESRRA,"estrogen related receptor, alpha",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|regulation of ossification|regulation of cell proliferation|steroid hormone mediated signaling pathway|regulation of osteoblast differentiation|regulation of osteoclast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cartilage development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|steroid binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,-0.1,0.236,-0.1,0.126,-0.126,0.839,0,0,-1.6,1.4
ENSMUSG00000047141,ZFP654,zinc finger protein 654,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0.1,0.108,10,-0.2,0.408,0.1,0.123,0.123,0.84,0,0,-1.3,1.5
ENSMUSG00000044519,ZFP488,zinc finger protein 488,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|oligodendrocyte development|negative regulation of transcription, DNA-templated|positive regulation of oligodendrocyte differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|protein binding|metal ion binding|,10,0,0,10,-0.3,0.282,-0.2,0.123,-0.123,0.84,0,0,-1.7,1.1
ENSMUSG00000090258,CHURC1,churchill domain containing 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|mesoderm development|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|zinc ion binding|metal ion binding|,10,0,0,10,-0.2,0.689,-0.1,0.122,-0.122,0.84,0,0,-1.1,1.7
ENSMUSG00000070495,CTCFL,CCCTC-binding factor (zinc finger protein)-like,nucleus|cytoplasm|,"regulation of gene expression by genetic imprinting|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of gene expression|chromatin modification|histone methylation|DNA methylation involved in gamete generation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of histone H3-K4 methylation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|protein binding|histone binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|,9,0,0,9,0.3,0.834,0.2,0.119,0.119,0.841,0,0,-0.9,1.9
ENSMUSG00000041886,MACC1,metastasis associated in colon cancer 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0103,10,-0.1,0.119,-0.1,0.118,-0.118,0.842,0,0,-1.8,1.1
ENSMUSG00000028957,PER3,period circadian clock 3,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|circadian rhythm|circadian regulation of gene expression|regulation of circadian sleep/wake cycle, sleep|regulation of circadian sleep/wake cycle, sleep|rhythmic process|",signal transducer activity|protein binding|kinase binding|ubiquitin protein ligase binding|,9,0.2,0.305,9,-0.1,0.00897,0.1,0.117,0.117,0.842,0,0,-1.3,1.7
ENSMUSG00000038446,CDC40,cell division cycle 40,nucleus|spliceosomal complex|catalytic step 2 spliceosome|,mRNA processing|RNA splicing|,poly(A) RNA binding|,10,0,0,10,-0.1,0.318,-0.1,0.116,-0.116,0.843,0,0,-1.7,1.4
ENSMUSG00000055782,ABCD2,"ATP-binding cassette, sub-family D (ALD), member 2",mitochondrion|peroxisome|peroxisomal membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,very long-chain fatty acid metabolic process|fatty acid beta-oxidation|fatty acid beta-oxidation|transport|positive regulation of fatty acid beta-oxidation|very long-chain fatty acid catabolic process|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|protein homodimerization activity|",10,0.2,0.385,10,0,0,0.1,0.112,0.112,0.844,0,0,-1.3,1.6
ENSMUSG00000034818,CELF5,"CUGBP, Elav-like family member 5",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0091,10,-0.8,1.15,0.1,0.107,0.107,0.846,0,0,-1.9,1
ENSMUSG00000026432,AVPR1B,arginine vasopressin receptor 1B,plasma membrane|membrane|integral component of membrane|,regulation of systemic arterial blood pressure by vasopressin|signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|vasopressin receptor activity|peptide hormone binding|protein homodimerization activity|,10,0,0,10,-0.1,0.196,-0.1,0.104,-0.104,0.847,0,0,-1.6,1.3
ENSMUSG00000022526,ZFP251,zinc finger protein 251,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.2,0.804,10,0,0,0.1,0.103,0.103,0.847,0,0,-1.1,1.8
ENSMUSG00000047473,ZFP30,zinc finger protein 30,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.981,10,0,0,-0.1,0.103,-0.103,0.847,0,0,-1.6,1.3
ENSMUSG00000074158,9830147E19RIK,RIKEN cDNA 9830147E19 gene,cellular_component|,"regulation of transcription, DNA-templated|cellular response to heat|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.0271,10,0.1,0.085,0.1,0.102,0.102,0.848,0,0,-1.3,1.7
ENSMUSG00000030443,ZFP583,zinc finger protein 583,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0.5,0.443,-0.1,0.0933,-0.0933,0.851,0,0,-0.7,2
ENSMUSG00000017421,ZFP207,zinc finger protein 207,"chromosome, centromeric region|kinetochore|nucleus|nucleus|chromosome|microtubule|",mitotic sister chromatid segregation|cell cycle|chromosome segregation|mitotic nuclear division|mitotic spindle assembly checkpoint|attachment of spindle microtubules to kinetochore|protein stabilization|cell division|regulation of chromosome segregation|,microtubule binding|heparin binding|poly(A) RNA binding|metal ion binding|,9,0.1,0.0263,8,-0.4,1.18,-0.1,0.0924,-0.0924,0.851,0,0,-1.9,1
ENSMUSG00000033458,FAN1,FANCD2/FANCI-associated nuclease 1,nucleus|,"double-strand break repair via homologous recombination|DNA catabolic process, endonucleolytic|DNA repair|nucleotide-excision repair|cellular response to DNA damage stimulus|nucleotide-excision repair, DNA incision|","nuclease activity|endonuclease activity|exonuclease activity|phosphodiesterase I activity|5'-3' exonuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|5'-flap endonuclease activity|ubiquitin binding|metal ion binding|",10,-0.3,0.49,10,0.5,2.34,0.2,0.0902,0.0902,0.852,0,0,-1.3,1.5
ENSMUSG00000022914,BRWD1,bromodomain and WD repeat domain containing 1,nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|cytoskeleton organization|regulation of cell shape|",protein binding|,10,0,0,10,0.2,0.497,0.1,0.0894,0.0894,0.853,0,0,-1.1,1.8
ENSMUSG00000039068,ZZZ3,"zinc finger, ZZ domain containing 3",nucleus|Ada2/Gcn5/Ada3 transcription activator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|chromatin binding|zinc ion binding|metal ion binding|,10,-0.1,0.13,10,0.1,0.059,0.1,0.0883,0.0883,0.853,0,0,-1.3,1.6
ENSMUSG00000028988,CTNNBIP1,catenin beta interacting protein 1,nucleus|nucleus|nucleus|cytoplasm|cytoplasm|cytosol|cytosol|beta-catenin destruction complex|beta-catenin destruction complex|,negative regulation of transcription from RNA polymerase II promoter|branching involved in ureteric bud morphogenesis|regulation of vascular permeability involved in acute inflammatory response|anterior/posterior pattern specification|Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of protein complex assembly|negative regulation of protein binding|negative regulation of DNA binding|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of monocyte differentiation|positive regulation of osteoblast differentiation|negative regulation of smooth muscle cell proliferation|negative regulation of transcription initiation from RNA polymerase II promoter|negative regulation of mesenchymal cell proliferation|,protein binding|beta-catenin binding|beta-catenin binding|armadillo repeat domain binding|,9,-0.2,0.213,9,0,0,-0.1,0.0877,-0.0877,0.853,0,0,-1.7,1.3
ENSMUSG00000004127,TRMT10A,tRNA methyltransferase 10A,extracellular vesicular exosome|,magnesium ion homeostasis|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.3,0.882,10,0,0,-0.1,0.0871,-0.0871,0.853,0,0,-1.8,1.1
ENSMUSG00000028949,SMARCD3,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3",nuclear chromatin|nucleus|nucleus|cytoplasm|SWI/SNF complex|npBAF complex|npBAF complex|nBAF complex|,"positive regulation of neuroblast proliferation|heart morphogenesis|secondary heart field specification|cardiac right ventricle formation|nucleosome disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|nervous system development|chromatin modification|muscle cell differentiation|regulation of protein binding|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",receptor binding|protein binding|transcription factor binding|ligand-dependent nuclear receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|nuclear hormone receptor binding|,10,0.3,0.622,10,-0.2,0.51,0.1,0.0803,0.0803,0.856,0,0,-0.9,2
ENSMUSG00000026896,IFIH1,interferon induced with helicase C domain 1,nucleus|cytoplasm|,immune system process|response to virus|protein sumoylation|positive regulation of interferon-alpha production|positive regulation of interferon-beta production|regulation of apoptotic process|innate immune response|defense response to virus|,"nucleotide binding|DNA binding|RNA binding|double-stranded RNA binding|single-stranded RNA binding|helicase activity|protein binding|ATP binding|zinc ion binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|ribonucleoprotein complex binding|metal ion binding|",10,-0.1,0.0523,10,-0.1,0.0349,-0.1,0.0793,-0.0793,0.857,0,0,-1.5,1.5
ENSMUSG00000054519,ZFP867,zinc finger protein 867,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.01,10,-0.1,0.0767,-0.1,0.079,-0.079,0.857,0,0,-1.3,1.6
ENSMUSG00000021962,DCP1A,DCP1 decapping enzyme homolog A (S. cerevisiae),cytoplasmic mRNA processing body|nucleus|transcription factor complex|cytoplasm|membrane|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|transforming growth factor beta receptor signaling pathway|positive regulation of transcription, DNA-templated|",GPI-anchor transamidase activity|transcription factor binding|hydrolase activity|identical protein binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0.1,0.266,10,0,0,0.1,0.0765,0.0765,0.858,0,0,-1.1,1.8
ENSMUSG00000044927,H1FX,"H1 histone family, member X",nucleus|chromosome|nucleolus|,biological_process|,DNA binding|protein binding|poly(A) RNA binding|,10,0,0,10,-0.2,0.47,-0.1,0.0693,-0.0693,0.86,0,0,-1.7,1.1
ENSMUSG00000047417,REXO1,"REX1, RNA exonuclease 1 homolog (S. cerevisiae)",nucleus|,biological_process|,molecular_function|nucleic acid binding|nuclease activity|exonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,9,-0.1,0.144,9,0,0,-0.1,0.0693,-0.0693,0.86,0,0,-1.4,1.6
ENSMUSG00000045991,ONECUT2,"one cut domain, family member 2",nucleus|,"liver development|regulation of cell-matrix adhesion|epithelial cell development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|anatomical structure morphogenesis|positive regulation of cell migration|negative regulation of transforming growth factor beta receptor signaling pathway|pancreas development|endocrine pancreas development|cilium assembly|cell fate commitment|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|peripheral nervous system neuron development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|,10,0,0,10,-0.4,0.26,-0.1,0.0683,-0.0683,0.861,0,0,-1.8,1
ENSMUSG00000021066,ATL1,atlastin GTPase 1,Golgi cis cisterna|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|cell projection|,GTP catabolic process|endoplasmic reticulum organization|axonogenesis|protein homooligomerization|,nucleotide binding|GTPase activity|GTP binding|hydrolase activity|identical protein binding|,10,0.3,0.545,10,0,0,0.1,0.0683,0.0683,0.861,0,0,-1,1.8
ENSMUSG00000075592,NYNRIN,NYN domain and retroviral integrase containing,cellular_component|membrane|integral component of membrane|,biological_process|DNA integration|,molecular_function|nucleic acid binding|,10,0.2,0.151,10,-0.1,0.132,0.1,0.064,0.064,0.862,0,0,-1.1,1.8
ENSMUSG00000014329,BICC1,bicaudal C homolog 1 (Drosophila),cytoplasm|,multicellular organismal development|negative regulation of canonical Wnt signaling pathway|,RNA binding|poly(A) RNA binding|,10,0.3,1.13,10,0,0,0.1,0.0608,0.0608,0.863,0,0,-1.3,1.5
ENSMUSG00000034071,ZFP551,zinc fingr protein 551,intracellular|nucleus|,"regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|metal ion binding|,10,0.2,0.285,10,-0.7,1.64,0.1,0.0596,0.0596,0.864,0,0,-2,0.8
ENSMUSG00000047171,HELT,helt bHLH transcription factor,nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|suckling behavior|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|central nervous system development|post-embryonic development|multicellular organismal aging|gene expression|GABAergic neuron differentiation in basal ganglia|cell differentiation|neuron differentiation|multicellular organism growth|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|protein homodimerization activity|protein dimerization activity|,10,0.2,0.642,10,0,0,0.1,0.058,0.058,0.865,0,0,-1.4,1.5
ENSMUSG00000021098,4930447C04RIK,RIKEN cDNA 4930447C04 gene,cellular_component|,multicellular organismal development|regulation of sequence-specific DNA binding transcription factor activity|,molecular_function|,10,-0.2,0.691,10,0,0,-0.1,0.0578,-0.0578,0.865,0,0,-1.5,1.4
ENSMUSG00000058298,MCM9,minichromosome maintenance complex component 9,nucleus|MCM8-MCM9 complex|MCM8-MCM9 complex|,double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|DNA repair|cellular response to DNA damage stimulus|cellular response to DNA damage stimulus|gamete generation|female gamete generation|,nucleotide binding|DNA binding|helicase activity|protein binding|ATP binding|hydrolase activity|,10,-0.5,2,9,0.3,1.39,-0.1,0.0568,-0.0568,0.865,0,0,-1.8,1
ENSMUSG00000021838,SAMD4,sterile alpha motif domain containing 4,cytoplasm|cell junction|cell projection|neuron projection|synapse|,regulation of translation|negative regulation of translation|positive regulation of translation|,translation repressor activity|poly(A) RNA binding|,10,0,0,10,-0.2,0.865,-0.1,0.0558,-0.0558,0.865,0,0,-1.6,1.3
ENSMUSG00000021362,GCM2,glial cells missing homolog 2 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular calcium ion homeostasis|cellular calcium ion homeostasis|multicellular organismal development|cell differentiation|cellular phosphate ion homeostasis|cellular phosphate ion homeostasis|negative regulation of apoptotic process|parathyroid gland development|parathyroid gland development|cellular response to organic substance|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|sequence-specific DNA binding|metal ion binding|,10,0.1,0.0858,10,0,0,0.1,0.0552,0.0552,0.866,0,0,-1.2,1.7
ENSMUSG00000039106,HTR5A,5-hydroxytryptamine (serotonin) receptor 5A,intracellular|rough endoplasmic reticulum|Golgi apparatus|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|dendrite|perikaryon|,"signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|serotonin receptor signaling pathway|cAMP-mediated signaling|",signal transducer activity|G-protein coupled receptor activity|serotonin receptor activity|,10,-0.1,0.00644,10,-0.1,0.0542,-0.1,0.0552,-0.0552,0.866,0,0,-2,0.9
ENSMUSG00000024266,ADAD2,adenosine deaminase domain containing 2,None,RNA processing|biological_process|,RNA binding|adenosine deaminase activity|,9,0,0,9,-0.2,0.339,-0.1,0.0504,-0.0504,0.867,0,0,-1.5,1.6
ENSMUSG00000033200,TPSG1,tryptase gamma 1,membrane|integral component of membrane|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0,0,10,1.2,0.739,-0.1,0.0498,-0.0498,0.868,0,0,-1.4,2
ENSMUSG00000027939,NUP210L,nucleoporin 210-like,cellular_component|membrane|integral component of membrane|,spermatid development|Sertoli cell development|,molecular_function|,10,0.1,0.16,10,0,0,0.1,0.0447,0.0447,0.869,0,0,-1.3,1.7
ENSMUSG00000055027,SMYD1,SET and MYND domain containing 1,nucleus|cytoplasm|,"chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|heart development|positive regulation of myotube differentiation|methylation|skeletal muscle cell differentiation|positive regulation of myoblast differentiation|negative regulation of transcription, DNA-templated|",DNA binding|transcription corepressor activity|protein binding|methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|metal ion binding|,10,-0.1,0.396,10,0.1,0.0095,-0.1,0.0445,-0.0445,0.869,0,0,-1.6,1.4
ENSMUSG00000048307,ANKRD46,ankyrin repeat domain 46,membrane|integral component of membrane|,None,None,10,0.2,0.00908,10,-0.3,0.956,-0.1,0.0428,-0.0428,0.87,0,0,-1.6,1.2
ENSMUSG00000030264,THUMPD3,THUMP domain containing 3,nucleolus|cytoplasm|,biological_process|methylation|,molecular_function|RNA binding|methyltransferase activity|transferase activity|,10,0,0,10,0.1,0.0772,0.1,0.0342,0.0342,0.873,0,0,-1.6,1.5
ENSMUSG00000050397,FOXL2,forkhead box L2,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|ovarian follicle development|ovarian follicle development|extraocular skeletal muscle development|apoptotic DNA fragmentation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|female somatic sex determination|cell differentiation|menstruation|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|embryonic eye morphogenesis|granulosa cell differentiation|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|estrogen receptor binding|ubiquitin conjugating enzyme binding|cysteine-type endopeptidase regulator activity involved in apoptotic process|sequence-specific DNA binding|,10,0,0,10,0.1,0.343,0.1,0.0329,0.0329,0.874,0,0,-1.6,1.5
ENSMUSG00000054893,ZFP667,zinc finger protein 667,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,-0.1,0.233,-0.1,0.029,-0.029,0.875,0,0,-1.8,1.2
ENSMUSG00000054459,VSNL1,visinin-like 1,None,None,calcium ion binding|metal ion binding|,10,-0.1,0.161,10,0.2,0.497,-0.1,0.0287,-0.0287,0.875,0,0,-1.2,1.6
ENSMUSG00000027204,FBN1,fibrillin 1,microfibril|microfibril|extracellular region|extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|extracellular matrix|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,skeletal system development|metanephros development|kidney development|heart development|sequestering of BMP in extracellular matrix|sequestering of TGFbeta in extracellular matrix|,extracellular matrix structural constituent|calcium ion binding|protein binding|,10,-0.1,0.0419,10,0,0,-0.1,0.0281,-0.0281,0.876,0,0,-1.6,1.4
ENSMUSG00000033883,D3ERTD254E,"DNA segment, Chr 3, ERATO Doi 254, expressed",cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.21,10,0,0,0.1,0.0258,0.0258,0.877,0,0,-1.1,1.8
ENSMUSG00000042002,FOXN4,forkhead box N4,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|retina layer formation|cell differentiation|amacrine cell differentiation|positive regulation of transcription, DNA-templated|neuron fate commitment|ventral spinal cord interneuron fate commitment|",enhancer sequence-specific DNA binding|enhancer sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.7,1.36,0.1,0.0226,0.0226,0.878,0,0,-0.6,2
ENSMUSG00000006378,GCAT,glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase),nucleus|mitochondrion|mitochondrion|mitochondrial inner membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.201,0.1,0.0221,0.0221,0.878,0,0,-1.6,1.5
ENSMUSG00000045440,INSM2,insulinoma-associated 2,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|transcription corepressor activity|metal ion binding|,10,0,0,10,-0.1,0.278,-0.1,0.02,-0.02,0.879,0,0,-1.8,1.2
ENSMUSG00000000317,BCL6B,"B cell CLL/lymphoma 6, member B",nucleus|,negative regulation of transcription from RNA polymerase II promoter|,nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,0,0,10,-0.3,1.41,-0.1,0.0195,-0.0195,0.879,0,0,-1.3,1.7
ENSMUSG00000055239,KCMF1,potassium channel modulatory factor 1,None,protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.7,1.99,10,0.1,0.136,-0.1,0.0175,-0.0175,0.88,0,0,-2,0.8
ENSMUSG00000037991,RMI2,"RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)",nucleus|cytoplasm|,DNA replication|biological_process|,molecular_function|DNA binding|,10,0,0,10,0.2,0.383,0.1,0.017,0.017,0.88,0,0,-1.2,1.7
ENSMUSG00000022020,NAA16,"N(alpha)-acetyltransferase 16, NatA auxiliary subunit",cytoplasm|NatA complex|extracellular vesicular exosome|,N-terminal protein amino acid acetylation|negative regulation of apoptotic process|protein stabilization|,peptide alpha-N-acetyltransferase activity|ribosome binding|,10,0,0,10,0.2,0.863,0.1,0.0164,0.0164,0.88,0,0,-1.2,1.7
ENSMUSG00000045608,DBX2,developing brain homeobox 2,cellular_component|nucleus|,biological_process|,DNA binding|,10,0.1,0.124,10,0,0,0.1,0.0127,0.0127,0.881,0,0,-1.2,1.7
ENSMUSG00000041079,RWDD2B,RWD domain containing 2B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.123,-0.1,0.0111,-0.0111,0.882,0,0,-1.4,1.6
ENSMUSG00000048377,FOXI2,forkhead box I2,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.1,0.377,10,0,0,-0.1,0.00988,-0.00988,0.883,0,0,-1.4,1.7
ENSMUSG00000040158,TAX1BP3,Tax1 (human T cell leukemia virus type I) binding protein 3,intracellular|nucleus|cytoplasm|plasma membrane|membrane|extracellular vesicular exosome|,Rho protein signal transduction|negative regulation of cell proliferation|Wnt signaling pathway|regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|activation of Cdc42 GTPase activity|negative regulation of protein localization to cell surface|,protein binding|beta-catenin binding|protein C-terminus binding|,10,0.1,0.285,10,0,0,0.1,0.0047,0.0047,0.884,0,0,-1.4,1.6
ENSMUSG00000031409,TCEAL6,transcription elongation factor A (SII)-like 6,cellular_component|,translation|translational elongation|biological_process|,molecular_function|translation elongation factor activity|,10,0,0,10,-0.2,0.617,-0.1,0.0036,-0.0036,0.885,0,0,-1.7,1.2
ENSMUSG00000026058,KHDRBS2,"KH domain containing, RNA binding, signal transduction associated 2",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of signal transduction|",RNA binding|SH3/SH2 adaptor activity|poly(A) binding|poly(U) RNA binding|SH3 domain binding|SH2 domain binding|protein heterodimerization activity|,10,0.1,0.098,10,0,0,0.1,0.00316,0.00316,0.885,0,0,-1.1,1.8
ENSMUSG00000032089,IL10RA,"interleukin 10 receptor, alpha",plasma membrane|membrane|integral component of membrane|,cytokine-mediated signaling pathway|,interleukin-10 receptor activity|interleukin-10 binding|,9,-0.4,0.182,9,0,0,-0.1,0.00183,-0.00183,0.886,0,0,-1.7,1.4
ENSMUSG00000073043,ATOH1,atonal homolog 1 (Drosophila),nucleus|,"neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|nervous system development|axon guidance|brain development|cerebral cortex development|cell differentiation|neuron differentiation|inner ear morphogenesis|auditory receptor cell differentiation|auditory receptor cell differentiation|auditory receptor cell fate specification|auditory receptor cell fate determination|negative regulation of apoptotic process|positive regulation of auditory receptor cell differentiation|regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|inner ear development|positive regulation of inner ear receptor cell differentiation|",DNA binding|protein binding|chromatin DNA binding|sequence-specific DNA binding|protein dimerization activity|,10,0,0,10,0.3,0.529,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000092094,ZFP804B,zinc finger protein 804B,None,biological_process|,molecular_function|,10,-0.1,0.0572,10,1,0.619,0,0,0,0.886,0,0,-1.2,2
ENSMUSG00000020120,PLEK,pleckstrin,intracellular|cell|cytoplasm|membrane|ruffle membrane|,vesicle docking involved in exocytosis|integrin-mediated signaling pathway|positive regulation of platelet activation|negative regulation of inositol phosphate biosynthetic process|positive regulation of inositol-polyphosphate 5-phosphatase activity|cell projection organization|positive regulation of actin filament depolymerization|positive regulation of actin filament depolymerization|phospholipase C-inhibiting G-protein coupled receptor signaling pathway|cortical actin cytoskeleton organization|ruffle organization|actin cytoskeleton reorganization|positive regulation of actin filament bundle assembly|positive regulation of integrin activation|intracellular signal transduction|negative regulation of G-protein coupled receptor protein signaling pathway|phosphatidylinositol metabolic process|regulation of cell diameter|thrombin receptor signaling pathway|thrombin receptor signaling pathway|platelet aggregation|protein kinase C signaling|protein secretion by platelet|,"protein kinase C binding|protein homodimerization activity|phosphatidylinositol-3,4-bisphosphate binding|",10,-0.2,0.377,10,0,0,0,0,0,0.886,0,0,-1.6,1.4
ENSMUSG00000051977,PRDM9,PR domain containing 9,intracellular|nucleus|nucleoplasm|chromosome|,"meiotic gene conversion|transcription, DNA-templated|regulation of transcription, DNA-templated|meiotic nuclear division|spermatogenesis|positive regulation of reciprocal meiotic recombination|positive regulation of reciprocal meiotic recombination|chromatin modification|histone methylation|histone methylation|peptidyl-lysine methylation|methylation|histone lysine methylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|histone H3-K4 methylation|positive regulation of meiosis I|",nucleic acid binding|methyltransferase activity|recombination hotspot binding|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H3-K4 specific)|histone methyltransferase activity (H3-K4 specific)|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1,1.9
ENSMUSG00000020801,MED31,mediator complex subunit 31,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein complex assembly|negative regulation of fibroblast proliferation|limb development|",RNA polymerase II transcription cofactor activity|protein binding|protein complex binding|,10,-0.1,0.181,10,0.6,0.396,0,0,0,0.886,0,0,-1.3,1.8
ENSMUSG00000050058,PRM3,protamine 3,nucleosome|nucleus|chromosome|cytoplasm|,multicellular organismal development|spermatogenesis|cell differentiation|chromosome condensation|sperm motility|,DNA binding|,10,0,0,10,-0.2,0.348,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000035305,ROR1,receptor tyrosine kinase-like orphan receptor 1,integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,protein phosphorylation|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|phosphorylation|peptidyl-tyrosine phosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|Wnt-protein binding|",10,0,0,10,0,0,0,0,0,0.886,0,0,-1.7,1.4
ENSMUSG00000049985,ANKRD55,ankyrin repeat domain 55,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.4,1.7
ENSMUSG00000060257,SCRT2,"scratch homolog 2, zinc finger protein (Drosophila)",nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of neuron migration|",nucleic acid binding|DNA binding|metal ion binding|,10,0.1,0.0427,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000054034,TCEAL5,transcription elongation factor A (SII)-like 5,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|translation|translational elongation|biological_process|",molecular_function|translation elongation factor activity|,10,0,0,10,-0.1,0.086,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000031398,PLXNA3,plexin A3,intracellular|plasma membrane|membrane|integral component of membrane|,signal transduction|multicellular organismal development|axon guidance|hippocampus development|pyramidal neuron development|negative regulation of axon extension involved in axon guidance|negative chemotaxis|positive regulation of cytoskeleton organization|semaphorin-plexin signaling pathway|,receptor activity|semaphorin receptor activity|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000035930,CHST4,carbohydrate (chondroitin 6/keratan) sulfotransferase 4,Golgi membrane|Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|,carbohydrate metabolic process|N-acetylglucosamine metabolic process|protein sulfation|sulfur compound metabolic process|inflammatory response|leukocyte tethering or rolling|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0,0,10,-0.2,0.151,0,0,0,0.886,0,0,-1.6,1.3
ENSMUSG00000035277,ARX,aristaless related homeobox,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|neuron migration|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|axon guidance|globus pallidus development|olfactory bulb development|cerebral cortex tangential migration|embryonic olfactory bulb interneuron precursor migration|cell proliferation in forebrain|cerebral cortex GABAergic interneuron migration|cell differentiation|forebrain development|regulation of cell proliferation|lipid digestion|positive regulation of organ growth|epithelial cell fate commitment|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|chromatin binding|sequence-specific DNA binding|,10,-0.1,0.251,10,0.6,0.893,0,0,0,0.886,0,0,-1.1,1.9
ENSMUSG00000022330,OSR2,odd-skipped related 2,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|chondrocyte differentiation|positive regulation of cell proliferation|positive regulation of gene expression|cell differentiation|positive regulation of bone mineralization|osteoblast proliferation|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic skeletal limb joint morphogenesis|middle ear morphogenesis|odontogenesis|embryonic digit morphogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|pronephros development|positive regulation of epithelial cell proliferation|palate development|embryonic skeletal joint morphogenesis|head development|bone morphogenesis|eyelid development in camera-type eye|embryonic skeletal joint development|positive regulation of gastrulation|",nucleic acid binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0.1,0.091,0,0,0,0.886,0,0,-1.3,1.6
ENSMUSG00000056962,JMJD6,jumonji domain containing 6,nucleus|nucleus|nucleoplasm|nucleolus|plasma membrane|,"blood vessel development|kidney development|sprouting angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|cell surface receptor signaling pathway|multicellular organismal development|heart development|RNA splicing|chromatin modification|peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine|cell differentiation|lung development|T cell differentiation in thymus|macrophage activation|apoptotic cell clearance|recognition of apoptotic cell|recognition of apoptotic cell|regulation of mRNA splicing, via spliceosome|regulation of mRNA splicing, via spliceosome|erythrocyte development|oxidation-reduction process|retina development in camera-type eye|histone H3-R2 demethylation|histone H4-R3 demethylation|","sulfonate dioxygenase activity|RNA binding|single-stranded RNA binding|receptor activity|iron ion binding|protein binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|histone demethylase activity (H3-R2 specific)|histone demethylase activity (H4-R3 specific)|hypophosphite dioxygenase activity|identical protein binding|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|peptidyl-lysine 5-dioxygenase activity|",10,0.1,0.00355,10,0,0,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000033837,FOXH1,forkhead box H1,nuclear chromatin|nucleus|nucleus|transcription factor complex|transcription factor complex|activin responsive factor complex|activin responsive factor complex|,"negative regulation of transcription from RNA polymerase II promoter|heart looping|secondary heart field specification|outflow tract morphogenesis|cardiac right ventricle morphogenesis|ventricular trabecula myocardium morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|determination of left/right symmetry|anterior/posterior pattern specification|negative regulation of intracellular estrogen receptor signaling pathway|embryonic heart tube anterior/posterior pattern specification|aorta morphogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|axial mesoderm development|negative regulation of androgen receptor signaling pathway|negative regulation of androgen receptor activity|",RNA polymerase II transcription cofactor activity|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein domain specific binding|bHLH transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|SMAD binding|SMAD binding|androgen receptor binding|co-SMAD binding|R-SMAD binding|R-SMAD binding|,9,0,0,9,0,0,0,0,0,0.886,0,0,-2,1
ENSMUSG00000090264,EIF4EBP3,eukaryotic translation initiation factor 4E binding protein 3,membrane|,regulation of translation|biological_process|negative regulation of translation|negative regulation of translational initiation|,molecular_function|eukaryotic initiation factor 4E binding|,10,0,0,10,0.2,0.384,0,0,0,0.886,0,0,-1.2,1.8
ENSMUSG00000024423,IMPACT,"impact, RWD domain protein",cytoplasm|,negative regulation of protein phosphorylation|regulation of translation|regulation of translational initiation|,protein binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.8,1.3
ENSMUSG00000044400,SOWAHD,sosondowah ankyrin repeat domain family member D,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0662,0,0,0,0.886,0,0,-1.2,1.8
ENSMUSG00000021255,ESRRB,"estrogen related receptor, beta",nucleus|,"in utero embryonic development|trophectodermal cellular morphogenesis|trophectodermal cell proliferation|embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|stem cell maintenance|steroid hormone mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II distal enhancer sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|transcription coactivator activity|steroid binding|protein binding|transcription factor binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,-0.3,0.346,0,0,0,0.886,0,0,-1.8,1.1
ENSMUSG00000034227,FOXJ1,forkhead box J1,nucleus|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|central tolerance induction|negative regulation of germinal center formation|positive regulation of central B cell tolerance induction|negative regulation of humoral immune response mediated by circulating immunoglobulin|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|humoral immune response|actin cytoskeleton organization|regulation of epithelial cell differentiation|negative regulation of NF-kappaB transcription factor activity|activation of Rho GTPase activity|negative regulation of T cell differentiation in thymus|establishment of apical/basal cell polarity|negative regulation of T cell proliferation|cilium assembly|negative regulation of interleukin-6 biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of B cell activation|leukocyte migration|cilium morphogenesis|left/right pattern formation|positive regulation of lung ciliated cell differentiation|",transcription regulatory region sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,9,0.2,0.503,9,-0.4,0.693,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000037279,OVOL2,ovo-like 2 (Drosophila),nucleus|,"angiogenesis|neural crest cell migration|neural fold formation|heart looping|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|heart development|negative regulation of cell proliferation|dorsal/ventral pattern formation|regulation of keratinocyte proliferation|regulation of keratinocyte proliferation|negative regulation of transcription by competitive promoter binding|negative regulation of keratinocyte differentiation|negative regulation of Notch signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|embryonic digestive tract morphogenesis|regulation of cell cycle|endocardium formation|heart trabecula formation|labyrinthine layer blood vessel development|",sequence-specific DNA binding RNA polymerase II transcription factor activity|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,0.1,0.156,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000053536,CSTF2T,"cleavage stimulation factor, 3' pre-RNA subunit 2, tau",intracellular|nucleus|,mRNA polyadenylation|mRNA processing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0.4,1.14,10,-0.7,1.98,0,0,0,0.886,0,0,-1.7,1.5
ENSMUSG00000002329,MDP1,magnesium-dependent phosphatase 1,extracellular vesicular exosome|,dephosphorylation|fructosamine metabolic process|,"phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|metal ion binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0,0,10,-0.1,0.132,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000064036,MRO,maestro,nucleus|nucleolus|,biological_process|,molecular_function|,10,0.2,0.251,10,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000037337,MAP4K1,mitogen-activated protein kinase kinase kinase kinase 1,intracellular|membrane|,MAPK cascade|activation of MAPKKK activity|protein phosphorylation|protein phosphorylation|protein phosphorylation|response to stress|cell proliferation|phosphorylation|peptidyl-serine phosphorylation|intracellular signal transduction|intracellular signal transduction|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|small GTPase regulator activity|protein binding|ATP binding|ATP binding|MAP kinase kinase kinase kinase activity|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,-0.3,1.12,0,0,0,0.886,0,0,-1.7,1.2
ENSMUSG00000035275,RAVER2,"ribonucleoprotein, PTB-binding 2",nucleus|cytoplasm|,None,nucleotide binding|nucleic acid binding|RNA binding|protein binding|poly(A) RNA binding|,10,0,0,10,0.1,0.137,0,0,0,0.886,0,0,-2,1
ENSMUSG00000059475,ZFP426,zinc finger protein 426,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.4,0.823,10,0,0,0,0,0,0.886,0,0,-1.8,1.1
ENSMUSG00000029817,TRA2A,transformer 2 alpha homolog (Drosophila),nucleus|nucleus|nucleolus|intracellular membrane-bounded organelle|,"mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|identical protein binding|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.6,1.4
ENSMUSG00000073209,KLF14,Kruppel-like factor 14,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.2,1.8
ENSMUSG00000060969,IRX1,Iroquois related homeobox 1 (Drosophila),nucleus|,"regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding|,10,0.2,0.11,10,-0.1,0.208,0,0,0,0.886,0,0,-1.4,1.5
ENSMUSG00000040620,DHX33,DEAH (Asp-Glu-Ala-His) box polypeptide 33,nucleus|nucleoplasm|nucleoplasm|nucleolus|nucleolus|,positive regulation of transcription from RNA polymerase I promoter|positive regulation of transcription from RNA polymerase I promoter|,nucleotide binding|rDNA binding|rDNA binding|nucleic acid binding|helicase activity|ATP binding|ATP-dependent helicase activity|hydrolase activity|activating transcription factor binding|poly(A) RNA binding|,9,0,0,6,-0.8,0.281,0,0,0,0.886,0,0,-2,1.4
ENSMUSG00000036109,MBNL3,muscleblind-like 3 (Drosophila),nucleus|cytoplasm|,mRNA processing|multicellular organismal development|RNA splicing|regulation of RNA splicing|negative regulation of myoblast differentiation|,poly(A) RNA binding|metal ion binding|,10,0.1,0.0188,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000042279,H1FOO,"H1 histone family, member O, oocyte-specific",nucleosome|female germ cell nucleus|nucleus|chromosome|cytoplasm|extracellular vesicular exosome|,nucleosome assembly|meiotic nuclear division|nucleosome positioning|regulation of DNA methylation|negative regulation of stem cell differentiation|,DNA binding|nucleosomal DNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.1,1.8
ENSMUSG00000028034,FUBP1,far upstream element (FUSE) binding protein 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of gene expression|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|RNA binding|protein binding|poly(A) RNA binding|,10,0.3,0.316,9,-0.6,1.53,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000021775,NR1D2,"nuclear receptor subfamily 1, group D, member 2",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of lipid metabolic process|regulation of circadian rhythm|steroid hormone mediated signaling pathway|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|rhythmic process|regulation of inflammatory response|lipid homeostasis|regulation of energy homeostasis|regulation of skeletal muscle cell differentiation|",core promoter sequence-specific DNA binding|core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|thyroid hormone receptor activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0.4,0.457,10,-0.1,0.164,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000079215,ZFP664,zinc finger protein 664,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,1.1,1.13,0,0,0,0.886,0,0,-0.7,2
ENSMUSG00000041165,SPEM1,sperm maturation 1,cytoplasm|membrane|integral component of membrane|,multicellular organismal development|spermatogenesis|sperm individualization|cell differentiation|sperm motility|,None,10,0.3,0.878,10,0,0,0,0,0,0.886,0,0,-1.1,1.7
ENSMUSG00000056209,NPM3,nucleoplasmin 3,nucleus|nucleolus|,rRNA processing|rRNA transcription|,nucleic acid binding|protein binding|poly(A) RNA binding|,10,0.2,0.333,10,0,0,0,0,0,0.886,0,0,-1,2
ENSMUSG00000025265,FGD1,"FYVE, RhoGEF and PH domain containing 1",ruffle|cytoplasm|Golgi apparatus|cytoskeleton|lamellipodium|cell projection|,cytoskeleton organization|regulation of cell shape|actin cytoskeleton organization|regulation of Rho protein signal transduction|regulation of Cdc42 GTPase activity|positive regulation of GTPase activity|filopodium assembly|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|small GTPase binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000006931,LEPREL4,leprecan-like 4,synaptonemal complex|nucleus|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.107,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000035873,PAWR,"PRKC, apoptosis, WT1, regulator",nucleus|nucleus|cytoplasm|cytoplasm|actin filament|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|negative regulation of B cell proliferation|interleukin-2 biosynthetic process|negative regulation of T cell proliferation|positive regulation of amyloid precursor protein biosynthetic process|negative regulation of T cell receptor signaling pathway|actin filament bundle assembly|apoptotic signaling pathway|",actin binding|protein binding|enzyme binding|leucine zipper domain binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000049532,SALL2,sal-like 2 (Drosophila),nucleus|NuRD complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|neural tube development|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0.3,0.587,0,0,0,0.886,0,0,-1.1,1.7
ENSMUSG00000042477,TFAP2E,"transcription factor AP-2, epsilon",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",DNA binding|sequence-specific DNA binding transcription factor activity|protein homodimerization activity|protein heterodimerization activity|,10,-0.1,0.224,10,0.1,0.103,0,0,0,0.886,0,0,-1.2,1.7
ENSMUSG00000032727,MIER3,"mesoderm induction early response 1, family member 3",cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|chromatin binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000085795,ZFP703,zinc finger protein 703,nucleus|nucleus|cytoplasm|cytoplasm|nuclear matrix|protein complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|positive regulation of epithelial to mesenchymal transition|regulation of transforming growth factor beta receptor signaling pathway|regulation of transforming growth factor beta receptor signaling pathway|positive regulation of cell migration|positive regulation of mammary gland epithelial cell proliferation|positive regulation of mammary gland epithelial cell proliferation|negative regulation of homotypic cell-cell adhesion|adherens junction assembly|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|regulation of cell cycle|mammary gland epithelial cell differentiation|regulation of canonical Wnt signaling pathway|cellular response to estradiol stimulus|",nucleic acid binding|metal ion binding|repressing transcription factor binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000071064,ZFP827,zinc finger protein 827,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000028977,CASZ1,castor zinc finger 1,nucleus|cytoplasm|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|biological_process|",DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000038193,HAND2,heart and neural crest derivatives expressed transcript 2,nuclear chromatin|nucleus|nucleus|transcription factor complex|protein complex|,"angiogenesis|in utero embryonic development|heart looping|suckling behavior|heart morphogenesis|cardiac right ventricle formation|cardiac neural crest cell migration involved in outflow tract morphogenesis|regulation of secondary heart field cardioblast proliferation|apoptotic process involved in heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|heart development|adult heart development|mesenchymal cell proliferation|negative regulation of cardiac muscle cell apoptotic process|neural crest cell development|cell differentiation|odontogenesis of dentin-containing tooth|embryonic digit morphogenesis|negative regulation of apoptotic process|negative regulation of DNA binding|negative regulation of sequence-specific DNA binding transcription factor activity|tongue development|negative regulation of osteoblast differentiation|negative regulation of osteoblast differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|sympathetic nervous system development|thymus development|peripheral nervous system neuron development|palate development|mesenchyme development|cartilage morphogenesis|coronary artery morphogenesis|visceral serous pericardium development|cardiac neural crest cell development involved in outflow tract morphogenesis|cell proliferation involved in outflow tract morphogenesis|determination of heart left/right asymmetry|positive regulation of transcription regulatory region DNA binding|positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process|positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|AT DNA binding|transcription coactivator activity|protein binding|transcription factor binding|transcription factor binding|activating transcription factor binding|protein homodimerization activity|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein dimerization activity|E-box binding|E-box binding|E-box binding|,10,0.5,1.18,10,-0.1,0.116,0,0,0,0.886,0,0,-1.2,1.8
ENSMUSG00000041544,PTCHD2,patched domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|hedgehog receptor activity|,10,0.3,0.315,10,-0.1,0.0864,0,0,0,0.886,0,0,-1.2,1.7
ENSMUSG00000033423,ERI3,exoribonuclease 3,plasma membrane|,biological_process|,nucleic acid binding|nuclease activity|exonuclease activity|protein binding|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|poly(A) RNA binding|retroviral 3' processing activity|metal ion binding|,10,0.2,0.387,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000072294,KLF12,Kruppel-like factor 12,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,0.4,0.559,10,0,0,0,0,0,0.886,0,0,-0.9,1.9
ENSMUSG00000042121,SSH1,slingshot homolog 1 (Drosophila),nucleus|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|,cell morphogenesis|protein dephosphorylation|protein dephosphorylation|regulation of actin polymerization or depolymerization|regulation of lamellipodium assembly|dephosphorylation|actin cytoskeleton organization|regulation of cellular protein metabolic process|regulation of axonogenesis|cellular response to ATP|,DNA binding|actin binding|actin binding|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,0.2,0.164,10,0,0,0,0,0,0.886,0,0,-1.9,1.1
ENSMUSG00000007617,HOMER1,homer homolog 1 (Drosophila),cytoplasm|plasma membrane|membrane|Z disc|cell junction|axon|dendrite|neuron projection|neuron projection|neuronal cell body|costamere|dendritic shaft|apical part of cell|synapse|postsynaptic membrane|excitatory synapse|neuronal postsynaptic density|neuronal postsynaptic density|,skeletal muscle contraction|G-protein coupled glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway|protein localization to synapse|behavioral response to cocaine|skeletal muscle fiber development|chemical homeostasis within a tissue|response to calcium ion|positive regulation of calcium ion transport|regulation of calcium ion import|regulation of store-operated calcium entry|regulation of cation channel activity|,receptor binding|protein binding|type 5 metabotropic glutamate receptor binding|protein complex scaffold|G-protein coupled glutamate receptor binding|identical protein binding|ion channel binding|protein heterodimerization activity|scaffold protein binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000030087,KLF15,Kruppel-like factor 15,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|glial cell differentiation|regulation of gene expression|cardiac muscle hypertrophy in response to stress|glucose transport|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|glomerular visceral epithelial cell differentiation|negative regulation of peptidyl-lysine acetylation|negative regulation of peptidyl-lysine acetylation|",nucleic acid binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,-1.4,2.65,0,0,0,0.886,0,0,-2,0.6
ENSMUSG00000007872,ID3,inhibitor of DNA binding 3,nucleus|cytoplasm|microtubule cytoskeleton|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|regulation of DNA replication|transcription, DNA-templated|multicellular organismal development|heart development|muscle organ development|epithelial cell differentiation|positive regulation of apoptotic process|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of myoblast differentiation|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|regulation of cell cycle|",sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|protein domain specific binding|protein dimerization activity|,10,0,0,10,-0.2,0.649,0,0,0,0.886,0,0,-1.4,1.5
ENSMUSG00000052102,GNPDA1,glucosamine-6-phosphate deaminase 1,cell|cytoplasm|extracellular vesicular exosome|,carbohydrate metabolic process|fructose 6-phosphate metabolic process|glucosamine metabolic process|glucosamine catabolic process|N-acetylglucosamine metabolic process|generation of precursor metabolites and energy|acrosome reaction|fructose biosynthetic process|,glucosamine-6-phosphate deaminase activity|glucosamine-6-phosphate deaminase activity|glucosamine-6-phosphate deaminase activity|hydrolase activity|,9,0,0,9,0,0,0,0,0,0.886,0,0,-1.6,1.6
ENSMUSG00000028850,GPATCH3,G patch domain containing 3,cellular_component|,biological_process|,molecular_function|nucleic acid binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000054169,CEACAM10,carcinoembryonic antigen-related cell adhesion molecule 10,extracellular region|,sperm motility|,molecular_function|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.9,1
ENSMUSG00000040478,PRDM13,PR domain containing 13,cellular_component|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|neurogenesis|methylation|","rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|DNA binding|chromatin binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|protein binding|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0.2,0.361,0,0,0,0.886,0,0,-1.2,1.7
ENSMUSG00000054321,TAF4B,"TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor",nucleus|transcription factor complex|,regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|,DNA binding|NF-kappaB binding|,10,-0.1,0.0986,10,0.3,0.356,0,0,0,0.886,0,0,-1.6,1.6
ENSMUSG00000066797,ZFP648,zinc finger protein 648,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.05,10,0,0,0,0,0,0.886,0,0,-2,0.6
ENSMUSG00000066798,ZBTB6,zinc finger and BTB domain containing 6,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.1,0.0114,10,0.2,0.683,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000033767,D930015E06RIK,RIKEN cDNA D930015E06 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000040183,ANKRD6,ankyrin repeat domain 6,nucleus|cytoplasm|,"positive regulation of JNK cascade|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|positive regulation of Wnt signaling pathway, planar cell polarity pathway|",protein binding|,10,0.1,0.223,10,-0.3,1.3,0,0,0,0.886,0,0,-1.6,1.2
ENSMUSG00000005148,KLF5,Kruppel-like factor 5,nucleus|nucleus|cytoplasm|Golgi apparatus|plasma membrane|intracellular membrane-bounded organelle|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|microvillus assembly|regulation of microvillus assembly|skeletal muscle cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|intestinal epithelial cell development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000070780,RBM47,RNA binding motif protein 47,cellular_component|nucleus|,hematopoietic progenitor cell differentiation|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,9,-0.4,0.344,9,0,0,0,0,0,0.886,0,0,-1.8,1.3
ENSMUSG00000034968,LBX2,ladybird homeobox homolog 2 (Drosophila),cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|,10,-0.1,0.139,10,0,0,0,0,0,0.886,0,0,-1.2,1.8
ENSMUSG00000027338,PRND,prion protein dublet,plasma membrane|membrane|anchored component of membrane|,cellular copper ion homeostasis|protein homooligomerization|,copper ion binding|protein binding|,3,0,0,3,0,0,0,0,0,0.886,0,0,-1.9,1.7
ENSMUSG00000096010,HIST4H4,"histone cluster 4, H4",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.4,1.5
ENSMUSG00000059625,SOHLH1,spermatogenesis and oogenesis specific basic helix-loop-helix 1,nucleus|cytoplasm|,"ovarian follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|regulation of gene expression|cell differentiation|positive regulation of transcription, DNA-templated|oogenesis|",DNA binding|sequence-specific DNA binding transcription factor activity|protein dimerization activity|,10,0,0,10,0.2,0.202,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000017667,ZFP334,zinc finger protein 334,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.0401,10,-0.2,0.292,0,0,0,0.886,0,0,-1.3,1.6
ENSMUSG00000044595,DND1,dead end homolog 1 (zebrafish),nucleus|cytoplasm|cytoplasm|,multicellular organismal development|germ cell development|negative regulation of gene silencing by miRNA|,nucleotide binding|nucleic acid binding|RNA binding|protein binding|AU-rich element binding|,10,-0.6,0.219,10,0,0,0,0,0,0.886,0,0,-2,0.9
ENSMUSG00000022096,HR,hairless,histone deacetylase complex|nucleus|nuclear body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|protein heterooligomerization|oxidation-reduction process|","sulfonate dioxygenase activity|DNA binding|transcription corepressor activity|transcription corepressor activity|protein binding|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|vitamin D receptor binding|histone deacetylase binding|DNA-N1-methyladenine dioxygenase activity|metal ion binding|thyroid hormone receptor binding|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0,0,10,0,0,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000060678,HIST1H4C,"histone cluster 1, H4c",nuclear chromosome|nucleus|membrane|protein complex|extracellular vesicular exosome|,DNA replication-dependent nucleosome assembly|DNA replication-independent nucleosome assembly|negative regulation of megakaryocyte differentiation|,poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1,1.9
ENSMUSG00000056459,ZBTB25,zinc finger and BTB domain containing 25,nucleus|cytoplasm|,biological_process|,DNA binding|metal ion binding|,10,0.1,0.0314,10,-0.2,0.327,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000024013,FGD2,"FYVE, RhoGEF and PH domain containing 2",nucleus|cytoplasm|endosome|cytoskeleton|plasma membrane|membrane|cell projection|,regulation of Rho protein signal transduction|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|metal ion binding|,10,0,0,10,-0.5,0.116,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000044847,LSM11,U7 snRNP-specific Sm-like protein LSM11,nucleus|U7 snRNP|U7 snRNP|ribonucleoprotein complex|histone pre-mRNA 3'end processing complex|,mitotic S phase|mRNA processing|histone mRNA 3'-end processing|,RNA binding|protein binding|U7 snRNA binding|,10,0,0,10,1.2,1.56,0,0,0,0.886,0,0,-1.1,2
ENSMUSG00000054582,PABPC1L,"poly(A) binding protein, cytoplasmic 1-like",cellular_component|,oocyte maturation|mRNA polyadenylation|,molecular_function|RNA binding|,9,0,0,9,0,0,0,0,0,0.886,0,0,-1.3,1.8
ENSMUSG00000038700,HOXB5,homeobox B5,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|endothelial cell differentiation|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|embryonic skeletal system morphogenesis|embryonic skeletal system development|",RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000034610,ZCCHC11,"zinc finger, CCHC domain containing 11",extracellular space|nucleus|nucleolus|cytoplasm|cytoplasm|extracellular vesicular exosome|,cytokine production|miRNA metabolic process|miRNA catabolic process|stem cell maintenance|gene silencing by RNA|pre-miRNA processing|RNA 3'-end processing|RNA 3'-end processing|regulation of lipopolysaccharide-mediated signaling pathway|negative regulation of NF-kappaB transcription factor activity|positive regulation of interleukin-6 production|interleukin-6-mediated signaling pathway|,nucleic acid binding|protein binding|zinc ion binding|transferase activity|nucleotidyltransferase activity|poly(A) RNA binding|metal ion binding|RNA uridylyltransferase activity|RNA uridylyltransferase activity|,10,0,0,10,-0.1,0.144,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000029715,POP7,"processing of precursor 7, ribonuclease P family, (S. cerevisiae)",cellular_component|nucleus|cytoplasm|,tRNA processing|biological_process|,nucleic acid binding|ribonuclease P activity|hydrolase activity|poly(A) RNA binding|,5,0,0,5,0.1,0.135,0,0,0,0.886,0,0,-1.5,1.9
ENSMUSG00000053110,YAP1,yes-associated protein 1,nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytosol|membrane|,"vasculogenesis|embryonic heart tube morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|cell proliferation|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of keratinocyte proliferation|keratinocyte differentiation|keratinocyte differentiation|negative regulation of epithelial cell differentiation|notochord development|somatic stem cell maintenance|hippo signaling|regulation of cell proliferation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of organ growth|paraxial mesoderm development|lateral mesoderm development|contact inhibition|regulation of canonical Wnt signaling pathway|cellular response to gamma radiation|regulation of stem cell proliferation|regulation of stem cell proliferation|regulation of metanephric nephron tubule epithelial cell differentiation|positive regulation of canonical Wnt signaling pathway|regulation of RNA biosynthetic process|negative regulation of extrinsic apoptotic signaling pathway|",RNA polymerase II transcription factor binding transcription factor activity|chromatin binding|transcription coactivator activity|transcription coactivator activity|transcription corepressor activity|protein binding|transcription regulatory region DNA binding|proline-rich region binding|,10,0,0,10,-0.2,0.565,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000096199,PTRHD1,peptidyl-tRNA hydrolase domain containing 1,cellular_component|,protein dephosphorylation|biological_process|,molecular_function|aminoacyl-tRNA hydrolase activity|protein tyrosine phosphatase activity|hydrolase activity|,10,0.1,0.0943,10,0,0,0,0,0,0.886,0,0,-1.5,1.4
ENSMUSG00000022335,ZFAT,zinc finger and AT hook domain containing,nucleus|cytoplasm|,"hematopoietic progenitor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|hemopoiesis|positive regulation of transcription from RNA polymerase II promoter|spongiotrophoblast layer development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000028175,DEPDC1A,DEP domain containing 1a,intracellular|nucleus|transcriptional repressor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|intracellular signal transduction|negative regulation of transcription, DNA-templated|",GTPase activator activity|,10,-0.2,0.452,10,0.2,0.608,0,0,0,0.886,0,0,-1.2,1.7
ENSMUSG00000021597,ANKRD32,ankyrin repeat domain 32,nucleus|centrosome|,None,protein binding|,10,0,0,10,-0.5,0.239,0,0,0,0.886,0,0,-1.7,1.4
ENSMUSG00000014303,GLIS2,GLIS family zinc finger 2,nucleus|transcription factor complex|cytoplasm|nuclear speck|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|cell differentiation|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of smoothened signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription regulatory region DNA binding|metal ion binding|,10,0,0,10,0.1,0.0628,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000039391,CCDC81,coiled-coil domain containing 81,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.27,0,0,0,0.886,0,0,-1.5,1.4
ENSMUSG00000061809,TBPL2,TATA box binding protein like 2,nucleus|nucleus|cytoplasm|cytoplasm|,"transcription, DNA-templated|DNA-templated transcription, initiation|regulation of transcription, DNA-templated|multicellular organismal development|negative regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0.3,1.17,10,0,0,0,0,0,0.886,0,0,-1.2,1.8
ENSMUSG00000021604,IRX4,Iroquois related homeobox 4 (Drosophila),nucleus|transcription factor complex|,"regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|heart development|cell differentiation|",DNA binding|sequence-specific DNA binding|,10,0,0,10,0.3,0.894,0,0,0,0.886,0,0,-1.1,1.8
ENSMUSG00000063047,ZFP780B,zinc finger protein 780B,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,-0.2,0.669,10,0.1,0.0667,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000059878,ZFP422,zinc finger protein 422,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|odontogenesis|",nucleic acid binding|DNA binding|metal ion binding|,10,0.1,0.146,10,0,0,0,0,0,0.886,0,0,-1.4,1.7
ENSMUSG00000042372,DMRT3,doublesex and mab-3 related transcription factor 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|sex differentiation|adult walking behavior|transmission of nerve impulse|ventral spinal cord interneuron specification|cell differentiation|regulation of odontogenesis of dentin-containing tooth|male sex differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,0,0,10,1.1,1.09,0,0,0,0.886,0,0,-0.7,2
ENSMUSG00000020037,RFX4,"regulatory factor X, 4 (influences HLA class II expression)",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|dorsal spinal cord development|telencephalon development|cerebellar cortex morphogenesis|negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning|forebrain development|midbrain development|cilium assembly|positive regulation of transcription from RNA polymerase II promoter|regulation of protein processing|",DNA binding|chromatin binding|protein binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.6,1.4
ENSMUSG00000021476,HABP4,hyaluronic acid binding protein 4,nucleus|cytoplasm|cytoplasm|cytoplasm|sarcomere|,"transcription, DNA-templated|regulation of transcription, DNA-templated|hyaluronan metabolic process|negative regulation of DNA binding|cellular response to mechanical stimulus|",hyaluronic acid binding|,10,0.1,0.136,10,0,0,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000000690,HOXB6,homeobox B6,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|anterior/posterior pattern specification|erythrocyte homeostasis|embryonic skeletal system morphogenesis|embryonic skeletal system development|embryonic skeletal system development|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000026535,IFI202B,interferon activated gene 202B,None,cellular response to interferon-beta|,None,10,0,0,10,0,0,0,0,0,0.886,0,0,-1,2
ENSMUSG00000026572,TBX19,T-box 19,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|pituitary gland development|regulation of cell proliferation|cell fate commitment|regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",enhancer sequence-specific DNA binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,10,0.2,0.738,10,0,0,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000047821,TRIM16,tripartite motif-containing 16,intracellular|cytoplasm|cytoplasm|PML body|,"histone H3 acetylation|histone H4 acetylation|positive regulation of keratinocyte differentiation|positive regulation of transcription, DNA-templated|positive regulation of retinoic acid receptor signaling pathway|positive regulation of interleukin-1 beta secretion|response to growth hormone|",DNA binding|zinc ion binding|interleukin-1 binding|NACHT domain binding|metal ion binding|,10,-0.1,0.14,10,0,0,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000037307,BANF2,barrier to autointegration factor 2,nucleus|cytoplasm|,biological_process|,molecular_function|DNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000017707,SERINC3,serine incorporator 3,Golgi apparatus|plasma membrane|membrane|integral component of membrane|,positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,None,10,-0.2,0.208,10,0,0,0,0,0,0.886,0,0,-1.6,1.3
ENSMUSG00000022201,ZFR,zinc finger RNA binding protein,nucleus|chromosome|cytoplasm|,multicellular organismal development|,nucleic acid binding|DNA binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,0.1,0.151,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000038236,HOXA7,homeobox A7,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of cell-matrix adhesion|negative regulation of leukocyte migration|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|anterior/posterior pattern specification|negative regulation of keratinocyte differentiation|negative regulation of monocyte differentiation|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|embryonic skeletal system morphogenesis|stem cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|sequence-specific DNA binding|,10,0.1,0.115,10,-0.2,0.692,0,0,0,0.886,0,0,-1.6,1.3
ENSMUSG00000075704,TXNRD2,thioredoxin reductase 2,cytoplasm|mitochondrion|mitochondrion|axon|dendrite|neuronal cell body|,response to oxygen radical|heart development|hemopoiesis|cell redox homeostasis|oxidation-reduction process|,"thioredoxin-disulfide reductase activity|protein binding|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor|protein homodimerization activity|flavin adenine dinucleotide binding|NADP binding|",10,0,0,10,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000027737,SLC7A11,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 11",rough endoplasmic reticulum|cytoskeleton|plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,amino acid transmembrane transport|transport|amino acid transport|response to toxic substance|platelet aggregation|,amino acid transmembrane transporter activity|,10,0.3,0.339,10,0,0,0,0,0,0.886,0,0,-1.1,1.8
ENSMUSG00000040054,BAZ2A,"bromodomain adjacent to zinc finger domain, 2A",nucleus|chromatin silencing complex|nucleolus|rDNA heterochromatin|,"chromatin silencing at rDNA|chromatin silencing at rDNA|DNA methylation|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone deacetylation|histone H4-K20 methylation|histone H3-K9 methylation|heterochromatin assembly involved in chromatin silencing|heterochromatin assembly involved in chromatin silencing|histone H4 deacetylation|",DNA binding|RNA binding|protein binding|zinc ion binding|metal ion binding|lysine-acetylated histone binding|,10,0,0,10,0.1,0.0509,0,0,0,0.886,0,0,-1.3,1.6
ENSMUSG00000025470,ZFP511,zinc finger protein 511,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",DNA binding|metal ion binding|,10,0,0,10,-0.1,0.0447,0,0,0,0.886,0,0,-1.4,1.5
ENSMUSG00000039748,EXO1,exonuclease 1,nucleus|,"DNA catabolic process, endonucleolytic|DNA catabolic process, exonucleolytic|immune system process|humoral immune response mediated by circulating immunoglobulin|nucleobase-containing compound metabolic process|DNA repair|mismatch repair|DNA recombination|cellular response to DNA damage stimulus|meiotic nuclear division|somatic hypermutation of immunoglobulin genes|isotype switching|nucleic acid phosphodiester bond hydrolysis|","DNA binding|catalytic activity|nuclease activity|endonuclease activity|exonuclease activity|5'-3' exonuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|5'-3' exodeoxyribonuclease activity|phosphoric ester hydrolase activity|structure-specific DNA binding|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|single-stranded DNA 5'-3' exodeoxyribonuclease activity|metal ion binding|flap endonuclease activity|double-stranded DNA 5'-3' exodeoxyribonuclease activity|",10,-0.3,0.227,10,0,0,0,0,0,0.886,0,0,-1.8,1.1
ENSMUSG00000024483,ANKHD1,ankyrin repeat and KH domain containing 1,None,biological_process|,poly(A) RNA binding|,10,0.2,0.179,10,-0.1,0.257,0,0,0,0.886,0,0,-1.2,1.7
ENSMUSG00000033788,DYSF,dysferlin,cytoplasm|plasma membrane|membrane|integral component of membrane|lamellipodium|T-tubule|T-tubule|cytoplasmic vesicle|sarcolemma|sarcolemma|extracellular vesicular exosome|,plasma membrane repair|plasma membrane repair|vesicle fusion|,calcium ion binding|protein binding|phospholipid binding|calcium-dependent phospholipid binding|lipid binding|metal ion binding|,8,0.1,0.122,8,-0.1,0.333,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000045826,PTPRCAP,"protein tyrosine phosphatase, receptor type, C polypeptide-associated protein",plasma membrane|membrane|integral component of membrane|,None,None,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000068551,ZFP467,zinc finger protein 467,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,0,0,10,-0.1,0.253,0,0,0,0.886,0,0,-1.7,1.2
ENSMUSG00000028089,CHD1L,chromodomain helicase DNA binding protein 1-like,nucleus|cytoplasm|plasma membrane|,ATP catabolic process|DNA repair|chromatin remodeling|cellular response to DNA damage stimulus|,nucleotide binding|DNA binding|helicase activity|ATP binding|hydrolase activity|ATPase activity|,10,0.4,0.162,10,0,0,0,0,0,0.886,0,0,-1.1,1.8
ENSMUSG00000050919,ZFP366,zinc finger protein 366,nucleus|nucleus|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of intracellular estrogen receptor signaling pathway|response to estrogen|,transcription corepressor activity|estrogen receptor binding|,10,0,0,10,0.1,0.0481,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000050410,TCF19,transcription factor 19,nucleus|,None,None,10,-0.2,0.0766,10,1.1,0.611,0,0,0,0.886,0,0,-1.1,2
ENSMUSG00000004105,ANGPTL2,angiopoietin-like 2,extracellular region|extracellular vesicular exosome|,None,None,10,0.1,0.126,10,0,0,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000006673,QRICH1,glutamine-rich 1,nucleus|,biological_process|,molecular_function|,10,-0.3,0.301,10,0,0,0,0,0,0.886,0,0,-2,0.8
ENSMUSG00000048410,ZFP407,zinc finger protein 407,cellular_component|,biological_process|,molecular_function|,9,0,0,9,-0.5,0.662,0,0,0,0.886,0,0,-1.9,1.1
ENSMUSG00000031131,VGLL1,vestigial like 1 homolog (Drosophila),cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,10,0.1,0.0709,10,0,0,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000030446,ZFP273,zinc finger protein 273,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000022683,PLA2G10,"phospholipase A2, group X",extracellular region|,lipid metabolic process|phospholipid metabolic process|axon guidance|positive regulation of lipid storage|lipid catabolic process|positive regulation of cellular protein metabolic process|positive regulation of prostaglandin secretion|cholesterol homeostasis|regulation of macrophage activation|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of sequence-specific DNA binding transcription factor activity|lysophospholipid transport|positive regulation of arachidonic acid secretion|negative regulation of cholesterol efflux|,phospholipase activity|phospholipase A2 activity|calcium ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.4,1.7
ENSMUSG00000023781,HES7,hairy and enhancer of split 7 (Drosophila),nucleus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|skeletal system development|somitogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|Notch signaling pathway|multicellular organismal development|regulation of somitogenesis|post-anal tail morphogenesis|negative regulation of transcription, DNA-templated|rhythmic process|rhythmic process|",DNA binding|transcription factor binding|protein dimerization activity|,10,-0.1,0.0373,10,0.2,0.917,0,0,0,0.886,0,0,-1.3,1.6
ENSMUSG00000054383,PNMA1,paraneoplastic antigen MA1,nucleus|nucleolus|cytoplasm|focal adhesion|,inflammatory response to antigenic stimulus|,molecular_function|,10,0,0,10,0.2,0.213,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000021481,ZFP346,zinc finger protein 346,nucleus|nucleolus|nucleolus|cytoplasm|,positive regulation of apoptotic process|,nucleic acid binding|RNA binding|double-stranded RNA binding|double-stranded RNA binding|protein binding|zinc ion binding|enzyme binding|poly(A) RNA binding|metal ion binding|,10,0,0,10,-0.3,0.758,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000045333,ZFP423,zinc finger protein 423,nucleus|nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|Notch signaling pathway|multicellular organismal development|nervous system development|cell differentiation|positive regulation of BMP signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|protein binding|protein homodimerization activity|sequence-specific DNA binding|metal ion binding|protein heterodimerization activity|,10,-0.2,0.255,10,0,0,0,0,0,0.886,0,0,-1.3,1.8
ENSMUSG00000024561,MBD1,methyl-CpG binding domain protein 1,chromatin|heterochromatin|nucleus|chromosome|cytoplasm|nuclear matrix|nuclear speck|,"DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|protein binding|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000037235,MXD4,Max dimerization protein 4,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",DNA binding|protein binding|protein dimerization activity|,10,-0.1,0.0386,10,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000031738,IRX6,Iroquois related homeobox 6 (Drosophila),nucleus|,"regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding|,10,0.1,0.173,10,0,0,0,0,0,0.886,0,0,-1.1,1.9
ENSMUSG00000005373,MLXIPL,MLX interacting protein-like,nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytosol|,"negative regulation of transcription from RNA polymerase II promoter|regulation of glycolytic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|positive regulation of cell proliferation|response to glucose|glucose mediated signaling pathway|negative regulation of peptidyl-serine phosphorylation|glucose homeostasis|positive regulation of fatty acid biosynthetic process|positive regulation of glycolytic process|positive regulation of glycolytic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of lipid biosynthetic process|fatty acid homeostasis|negative regulation of cell cycle arrest|cellular response to glucose stimulus|negative regulation of oxidative phosphorylation|regulation of energy homeostasis|",DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|transcription factor binding|protein kinase binding|carbohydrate response element binding|sequence-specific DNA binding|protein heterodimerization activity|protein dimerization activity|,10,0.3,0.963,10,-0.2,0.139,0,0,0,0.886,0,0,-1.3,1.6
ENSMUSG00000055639,DACH1,dachshund 1 (Drosophila),nucleus|transcription factor complex|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|suckling behavior|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|respiratory gaseous exchange|cell proliferation|negative regulation of transcription by competitive promoter binding|negative regulation of cell migration|development of primary female sexual characteristics|negative regulation of fibroblast proliferation|negative regulation of fibroblast proliferation|RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of cell proliferation involved in contact inhibition|",RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|,9,0,0,9,0.1,0.0309,0,0,0,0.886,0,0,-1.4,1.7
ENSMUSG00000007035,MSH5,mutS homolog 5 (E. coli),synaptonemal complex|,ATP catabolic process|mismatch repair|meiotic nuclear division|meiosis I|synapsis|reciprocal meiotic recombination|female gamete generation|homologous chromosome segregation|chiasma assembly|,nucleotide binding|DNA binding|ATP binding|DNA-dependent ATPase activity|mismatched DNA binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000052676,ZMAT1,"zinc finger, matrin type 1",nucleus|,biological_process|,DNA binding|metal ion binding|,10,-0.6,0.853,10,0,0,0,0,0,0.886,0,0,-2,0.8
ENSMUSG00000091243,VGLL3,vestigial like 3 (Drosophila),cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|,10,0.2,0.316,10,-0.1,0.24,0,0,0,0.886,0,0,-1.4,1.6
ENSMUSG00000031667,AKTIP,thymoma viral proto-oncogene 1 interacting protein,cytoplasm|plasma membrane|membrane|HOPS complex|FHF complex|,positive regulation of protein phosphorylation|transport|apoptotic process|endosome organization|lysosome organization|endosome to lysosome transport|protein transport|positive regulation of protein binding|early endosome to late endosome transport|,acid-amino acid ligase activity|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000036959,BCORL1,BCL6 co-repressor-like 1,nucleus|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|chromatin modification|",molecular_function|,10,0.1,0.0975,10,0,0,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000032015,POU2F3,"POU domain, class 2, transcription factor 3",nucleus|transcription factor complex|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|epidermis development|epidermis development|keratinocyte differentiation|wound healing|negative regulation by host of viral transcription|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|sequence-specific DNA binding|protein dimerization activity|,10,0,0,9,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000070345,HSF5,heat shock transcription factor family member 5,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.1,0.109,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000038630,ZKSCAN16,zinc finger with KRAB and SCAN domains 16,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000029238,CLOCK,circadian locomotor output cycles kaput,nucleus|nucleus|transcription factor complex|transcription factor complex|chromosome|cytoplasm|chromatoid body|intracellular membrane-bounded organelle|,"DNA damage checkpoint|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular response to DNA damage stimulus|signal transduction|spermatogenesis|circadian rhythm|circadian rhythm|histone acetylation|histone acetylation|circadian regulation of gene expression|circadian regulation of gene expression|regulation of hair cycle|proteasome-mediated ubiquitin-dependent protein catabolic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|rhythmic process|regulation of insulin secretion|positive regulation of NF-kappaB transcription factor activity|response to redox state|cellular response to ionizing radiation|regulation of type B pancreatic cell development|negative regulation of glucocorticoid receptor signaling pathway|","RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|core promoter sequence-specific DNA binding|core promoter binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|histone acetyltransferase activity|histone acetyltransferase activity|signal transducer activity|protein binding|transcription factor binding|transferase activity|transferase activity, transferring acyl groups|chromatin DNA binding|sequence-specific DNA binding|protein dimerization activity|E-box binding|E-box binding|",10,0,0,10,0,0,0,0,0,0.886,0,0,-1.5,1.6
ENSMUSG00000051176,ZFP42,zinc finger protein 42,nucleus|cytoplasm|cytoplasm|protein complex|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|spermatid development|regulation of genetic imprinting|",nucleic acid binding|DNA binding|protein binding|sequence-specific DNA binding|metal ion binding|,10,-0.1,0.0214,10,0,0,0,0,0,0.886,0,0,-1.7,1.3
ENSMUSG00000033249,HSF4,heat shock transcription factor 4,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|eye development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|response to stress|positive regulation of cell proliferation|positive regulation of cell proliferation|histone H3-K9 demethylation|camera-type eye development|positive regulation of cell differentiation|positive regulation of transcription from RNA polymerase II promoter|cell development|protein homotrimerization|",DNA binding|sequence-specific DNA binding transcription factor activity|protein phosphatase binding|sequence-specific DNA binding|,10,0,0,10,-0.1,0.22,0,0,0,0.886,0,0,-1.6,1.4
ENSMUSG00000021375,KIF13A,kinesin family member 13A,cytoplasm|endosome|Golgi apparatus|centrosome|cytoskeleton|kinesin complex|microtubule|endosome membrane|membrane|midbody|trans-Golgi network membrane|,cytokinesis|transport|intracellular protein transport|microtubule-based movement|cell cycle|endosome to lysosome transport|protein transport|melanosome organization|cargo loading into vesicle|Golgi to plasma membrane protein transport|cell division|plus-end-directed vesicle transport along microtubule|,nucleotide binding|microtubule motor activity|protein binding|ATP binding|microtubule binding|,10,-0.4,2.04,10,0.1,0.0337,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000045896,PAIP2B,poly(A) binding protein interacting protein 2B,cellular_component|,negative regulation of translation|negative regulation of translational initiation|,"translation repressor activity, nucleic acid binding|poly(A) binding|",10,0.2,0.284,10,0,0,0,0,0,0.886,0,0,-1.8,1.3
ENSMUSG00000021327,ZKSCAN3,zinc finger with KRAB and SCAN domains 3,intracellular|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|autophagy|lysosome organization|negative regulation of autophagy|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|negative regulation of cellular senescence|",nucleic acid binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0.2,0.671,0,0,0,0.886,0,0,-1.7,1.4
ENSMUSG00000049600,ZBTB45,zinc finger and BTB domain containing 45,cellular_component|nucleus|,biological_process|,molecular_function|metal ion binding|,9,-0.3,0.621,9,0,0,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000032387,RBPMS2,RNA binding protein with multiple splicing 2,cellular_component|,biological_process|,nucleotide binding|molecular_function|nucleic acid binding|,10,-0.1,0.00283,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000046886,ZFP474,zinc finger protein 474,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0.1,0.0306,0,0,0,0.886,0,0,-1.6,1.6
ENSMUSG00000018727,CPSF4L,cleavage and polyadenylation specific factor 4-like,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.4,0.00892,10,-0.1,0.0434,0,0,0,0.886,0,0,-2,0.8
ENSMUSG00000009248,ASCL2,achaete-scute complex homolog 2 (Drosophila),nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|placenta development|transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|nervous system development|negative regulation of Schwann cell proliferation|cell differentiation|somatic stem cell maintenance|spongiotrophoblast differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|protein dimerization activity|E-box binding|,10,0.1,0.162,10,-0.1,0.003,0,0,0,0.886,0,0,-1.7,1.4
ENSMUSG00000030016,ZFML,"zinc finger, matrin-like",nucleus|intracellular membrane-bounded organelle|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleotide binding|nucleic acid binding|DNA binding|RNA binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,9,-0.3,0.136,10,0.2,0.251,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000071604,FAM189A2,"family with sequence similarity 189, member A2",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.00912,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000030380,MZF1,myeloid zinc finger 1,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|protein homodimerization activity|transcription regulatory region DNA binding|metal ion binding|,10,0.1,0.064,10,0,0,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000034685,FAM171A2,"family with sequence similarity 171, member A2",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.7,1.4
ENSMUSG00000024063,LBH,limb-bud and heart,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|regulation of gene expression|regulation of blood coagulation|positive regulation of transcription, DNA-templated|",None,10,0.1,0.0463,10,0,0,0,0,0,0.886,0,0,-1.6,1.4
ENSMUSG00000078302,FOXD1,forkhead box D1,nucleus|,"branching involved in ureteric bud morphogenesis|kidney development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|axon guidance|positive regulation of gene expression|positive regulation of BMP signaling pathway|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|dichotomous subdivision of terminal units involved in ureteric bud branching|nephrogenic mesenchyme development|metanephric nephron development|metanephric capsule development|metanephric capsule specification|pattern specification involved in metanephros development|positive regulation of kidney development|","RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|DNA binding, bending|sequence-specific DNA binding|sequence-specific DNA binding|",10,0,0,10,0,0,0,0,0,0.886,0,0,-1.6,1.5
ENSMUSG00000046201,SCAF8,SR-related CTD-associated factor 8,nucleus|spliceosomal complex|nuclear matrix|,transcription from RNA polymerase II promoter|mRNA processing|RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|protein domain specific binding|RNA polymerase core enzyme binding|RNA polymerase binding|,10,0.1,0.064,10,0,0,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000066838,ZFP772,zinc finger protein 772,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.7,1.4
ENSMUSG00000031326,CDX4,caudal type homeobox 4,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|blood vessel development|placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|anterior/posterior pattern specification|positive regulation of transcription from RNA polymerase II promoter|labyrinthine layer development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding|,10,-0.1,0.217,10,1.1,1.07,0,0,0,0.886,0,0,-0.9,2
ENSMUSG00000030001,FIGLA,folliculogenesis specific basic helix-loop-helix,nucleus|transcription factor complex|transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|cell differentiation|oogenesis|",DNA binding|transcription factor binding|transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|protein dimerization activity|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.2,1.8
ENSMUSG00000047067,DUSP28,dual specificity phosphatase 28,intracellular|,protein dephosphorylation|JNK cascade|dephosphorylation|,phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,9,0,0,9,0,0,0,0,0,0.886,0,0,-1.6,1.6
ENSMUSG00000038765,LMX1B,LIM homeobox transcription factor 1 beta,nucleus|nucleus|,"neuron migration|trabecular meshwork development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|multicellular organismal development|cell proliferation|regulation of gene expression|cerebellum morphogenesis|central nervous system neuron development|neuron differentiation|collagen fibril organization|embryonic limb morphogenesis|midbrain development|limb morphogenesis|organ growth|camera-type eye development|positive regulation of transcription from RNA polymerase II promoter|dopaminergic neuron differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.886,0,0,-1.3,1.7
ENSMUSG00000004996,MRI1,methylthioribose-1-phosphate isomerase homolog (S. cerevisiae),nucleus|nucleolus|cytoplasm|cytoplasm|,cellular amino acid biosynthetic process|methionine biosynthetic process|L-methionine salvage from methylthioadenosine|cellular metabolic process|cellular biosynthetic process|,isomerase activity|identical protein binding|S-methyl-5-thioribose-1-phosphate isomerase activity|,9,0,0,9,-0.4,1.03,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000018862,OTOP3,otopetrin 3,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.253,0,0,0,0.886,0,0,-1.8,1.2
ENSMUSG00000033439,TRMT13,tRNA methyltransferase 13,cellular_component|,tRNA processing|biological_process|methylation|,methyltransferase activity|transferase activity|metal ion binding|,10,0,0,10,0.3,0.144,0,0,0,0.886,0,0,-1.1,1.8
ENSMUSG00000007209,CEACAM9,carcinoembryonic antigen-related cell adhesion molecule 9,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.383,0,0,0,0.886,0,0,-1.5,1.5
ENSMUSG00000044617,ZBTB39,zinc finger and BTB domain containing 39,cellular_component|nucleus|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.122,10,0,0,0,0,0,0.886,0,0,-1.1,1.8
ENSMUSG00000040552,C3AR1,complement component 3a receptor 1,plasma membrane|membrane|integral component of membrane|,complement receptor mediated signaling pathway|tolerance induction to nonself antigen|chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|regulation of blood pressure|positive regulation vascular endothelial growth factor production|positive regulation of macrophage chemotaxis|positive regulation of cell migration|positive regulation of angiogenesis|positive regulation of smooth muscle cell proliferation|positive regulation of glomerular mesangial cell proliferation|positive regulation of neutrophil chemotaxis|positive regulation of DNA biosynthetic process|,complement component C3a binding|signal transducer activity|G-protein coupled receptor activity|anaphylatoxin receptor activity|C3a anaphylatoxin receptor activity|,10,3.1,257,10,3,258,3,515,515,1.00E-05,1,1,2.8,3.7
ENSMUSG00000030536,IQGAP1,IQ motif containing GTPase activating protein 1,intracellular|nucleus|cytoplasm|cytoplasm|microtubule|plasma membrane|cell-cell junction|membrane|lateral plasma membrane|cell junction|midbody|ribonucleoprotein complex|ribonucleoprotein complex|extrinsic component of cytoplasmic side of plasma membrane|cell leading edge|cytoplasmic ribonucleoprotein granule|neuron projection|protein complex|extracellular vesicular exosome|,regulation of cytokine production|signal transduction|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|small GTPase mediated signal transduction|fibroblast growth factor receptor signaling pathway|negative regulation of dephosphorylation|cellular response to platelet-derived growth factor stimulus|cellular response to fibroblast growth factor stimulus|positive regulation of protein kinase activity|positive regulation of protein kinase activity|platelet-derived growth factor receptor signaling pathway|regulation of small GTPase mediated signal transduction|cellular response to calcium ion|cellular response to epidermal growth factor stimulus|cellular response to epidermal growth factor stimulus|positive regulation of protein serine/threonine kinase activity|,"GTPase activator activity|Ras GTPase activator activity|protein binding|calmodulin binding|phosphatidylinositol-3,4,5-trisphosphate binding|Rho GTPase binding|protein kinase binding|protein phosphatase binding|protein complex binding|protein serine/threonine kinase activator activity|Rac GTPase binding|",9,2,131,9,1.6,43.9,1.8,174,174,1.00E-05,1,1,1.5,2.3
ENSMUSG00000039901,9130011E15RIK,RIKEN cDNA 9130011E15 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.3,50,10,2.6,63.3,2.2,107,107,1.00E-05,1,1,1.6,3
ENSMUSG00000063234,GPR84,G protein-coupled receptor 84,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,1.1,49.3,10,1.7,35.9,1.1,84.5,84.5,1.00E-05,1,1,0.9,1.7
ENSMUSG00000028398,TMEM261,transmembrane protein 261,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-1.9,52.3,10,-1.1,28.9,-1.5,78.2,-78.2,1.00E-05,1,1,-2.3,-1.1
ENSMUSG00000037966,NINJ1,ninjurin 1,membrane|integral component of membrane|,positive regulation of cell-matrix adhesion|cell adhesion|tissue regeneration|hyaloid vascular plexus regression|,None,10,1.6,47,10,1,24,1,69.5,69.5,1.00E-05,1,1,0.8,1.8
ENSMUSG00000055447,CD47,"CD47 antigen (Rh-related antigen, integrin-associated signal transducer)",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|extracellular vesicular exosome|,cell adhesion|signal transduction|integrin-mediated signaling pathway|opsonization|positive regulation of cell proliferation|response to bacterium|cell migration|positive regulation of cell-cell adhesion|positive regulation of inflammatory response|positive regulation of phagocytosis|positive regulation of T cell activation|,protein binding|thrombospondin receptor activity|,10,-1.3,32.6,10,-2.2,38.4,-1.6,69.4,-69.4,1.00E-05,1,1,-2.5,-0.9
ENSMUSG00000035762,TMEM161B,transmembrane protein 161B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,19.8,10,1.4,40.9,1.2,54.6,54.6,1.00E-05,1,1,0.8,1.7
ENSMUSG00000027312,ATRN,attractin,extracellular space|cytoplasm|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,inflammatory response|response to oxidative stress|multicellular organismal development|cerebellum development|regulation of multicellular organism growth|myelination|pigmentation|,receptor activity|protein binding|carbohydrate binding|,10,1,26.8,10,0.9,25.1,1,51.5,51.5,5.00E-05,1,1,0.7,1.3
ENSMUSG00000050312,NSUN3,NOL1/NOP2/Sun domain family member 3,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-1.3,31,10,-0.8,20.6,-0.9,49.8,-49.8,7.00E-05,1,1,-1.6,-0.6
ENSMUSG00000026116,TMEM131,transmembrane protein 131,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.9,12,10,1,30.2,1,41.8,41.8,0.00062,1,1,0.7,1.4
ENSMUSG00000021733,SLC4A7,"solute carrier family 4, sodium bicarbonate cotransporter, member 7",cytoplasm|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|cytoplasmic vesicle|cell projection|,transport|ion transport|sodium ion transport|anion transport|visual perception|cochlear nucleus development|retinal cell programmed cell death|auditory receptor cell development|camera-type eye photoreceptor cell differentiation|retina vasculature morphogenesis in camera-type eye|,transporter activity|inorganic anion exchanger activity|anion transmembrane transporter activity|symporter activity|,10,1,16.9,10,0.9,24.8,0.9,41.1,41.1,0.00064,1,1,0.6,1.3
ENSMUSG00000027349,FAM98B,"family with sequence similarity 98, member B",tRNA-splicing ligase complex|,biological_process|,poly(A) RNA binding|,10,1,26.4,10,1.2,12.3,1.1,38,38,0.00077,1,1,0.8,1.6
ENSMUSG00000038141,TMEM181A,transmembrane protein 181A,cellular_component|,pathogenesis|,toxic substance binding|,10,1.4,22,10,1.2,15.8,1.3,37.2,37.2,0.00077,1,1,0.8,2
ENSMUSG00000021497,TXNDC15,thioredoxin domain containing 15,cellular_component|membrane|integral component of membrane|,biological_process|cell redox homeostasis|,molecular_function|,10,0.9,26.6,10,0.7,10.9,0.9,36.8,36.8,0.00077,1,1,0.6,1.3
ENSMUSG00000020921,TMEM101,transmembrane protein 101,cellular_component|membrane|integral component of membrane|,signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|,10,-0.7,19.5,10,-0.7,15.5,-0.7,34.6,-34.6,0.00085,1,1,-1.1,-0.5
ENSMUSG00000038178,SLC43A2,"solute carrier family 43, member 2",plasma membrane|membrane|integral component of membrane|,L-amino acid transport|transmembrane transport|L-alpha-amino acid transmembrane transport|,L-amino acid transmembrane transporter activity|,10,0.7,12.6,10,0.9,22.9,0.8,33.8,33.8,0.00091,1,1,0.5,1.7
ENSMUSG00000023923,TBC1D5,"TBC1 domain family, member 5",retromer complex|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,0.8,13.9,10,0.9,20.3,0.9,33.7,33.7,0.00092,1,1,0.5,1.2
ENSMUSG00000026858,FAM73B,"family with sequence similarity 73, member B",cellular_component|membrane|integral component of membrane|,bone development|,molecular_function|,10,-0.8,20.3,10,-0.9,9.33,-0.8,29,-29,0.00178,0,1,-1.3,-0.5
ENSMUSG00000034854,MFSD12,major facilitator superfamily domain containing 12,lysosomal membrane|membrane|integral component of membrane|,transport|,molecular_function|,10,0.9,16.1,10,0.9,12.6,0.9,28.4,28.4,0.00197,0,1,0.6,1.3
ENSMUSG00000044857,LEMD2,LEM domain containing 2,nucleus|integral component of nuclear inner membrane|membrane|membrane|integral component of membrane|nuclear membrane|nuclear membrane|,skeletal muscle cell differentiation|skeletal muscle cell differentiation|negative regulation of MAPK cascade|,molecular_function|,10,-1.2,30.3,10,0.7,2.3,-1.2,27.9,-27.9,0.00216,0,1,-2.4,-0.5
ENSMUSG00000027634,NDRG3,N-myc downstream regulated gene 3,cytoplasm|cytoplasm|extracellular vesicular exosome|,biological_process|,molecular_function|,9,1.5,26.6,9,0.7,4.06,1.3,27.9,27.9,0.00216,0,1,0.5,2.4
ENSMUSG00000054836,ELP6,elongator acetyltransferase complex subunit 6,Elongator holoenzyme complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell migration|",molecular_function|,9,1.1,13.6,9,1.2,14.2,1.2,27.1,27.1,0.00266,0,0,0.8,1.9
ENSMUSG00000031939,TAF1D,"TATA box binding protein (Tbp)-associated factor, RNA polymerase I, D",nucleus|RNA polymerase transcription factor SL1 complex|microtubule organizing center|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|,9,-1.6,23.6,10,0.9,6.53,-1.3,27,-27,0.00271,0,0,-2.9,-0.9
ENSMUSG00000051650,B3GNT2,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2",Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,protein glycosylation|axon guidance|sensory perception of smell|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-1,22.2,10,-0.7,4.89,-0.8,26.4,-26.4,0.00319,0,0,-1.5,-0.5
ENSMUSG00000074634,GM7120,predicted gene 7120,cellular_component|,biological_process|,molecular_function|,10,1.7,27.5,10,-0.1,0.227,1.6,25.2,25.2,0.00421,0,0,0.5,2.7
ENSMUSG00000034269,SETD5,SET domain containing 5,cellular_component|,biological_process|,molecular_function|,10,-0.8,9.61,10,-1,16.6,-1,25.1,-25.1,0.00429,0,0,-1.5,-0.6
ENSMUSG00000029090,GPR125,G protein-coupled receptor 125,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,1.7,24.2,10,1.3,1.75,1.6,25,25,0.00445,0,0,0.8,3
ENSMUSG00000033773,RPAP2,RNA polymerase II associated protein 2,"nucleus|nucleolus|cytoplasm|DNA-directed RNA polymerase II, holoenzyme|","transcription, DNA-templated|regulation of transcription, DNA-templated|snRNA transcription|dephosphorylation of RNA polymerase II C-terminal domain|",phosphoprotein phosphatase activity|CTD phosphatase activity|hydrolase activity|metal ion binding|,10,2,24,10,0.8,3.26,1.9,24.1,24.1,0.00588,0,0,0.8,3.6
ENSMUSG00000030614,TMEM126B,transmembrane protein 126B,cellular_component|mitochondrion|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.9,12.9,10,-1.1,11.9,-0.9,23.9,-23.9,0.00623,0,0,-1.4,-0.5
ENSMUSG00000026062,SLC9A2,"solute carrier family 9 (sodium/hydrogen exchanger), member 2",brush border|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|regulation of pH|protein localization|sodium ion transmembrane transport|sodium ion transmembrane transport|hydrogen ion transmembrane transport|,antiporter activity|sodium:proton antiporter activity|sodium:proton antiporter activity|,10,-1.6,23.4,10,-0.7,2.94,-1.3,23.2,-23.2,0.00768,0,0,-2.7,-0.4
ENSMUSG00000023827,AGPAT4,"1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)",cellular_component|membrane|integral component of membrane|,lipid metabolic process|biological_process|metabolic process|phospholipid biosynthetic process|,"molecular_function|1-acylglycerol-3-phosphate O-acyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",10,1,19.7,10,0.8,4.21,1,23.1,23.1,0.00795,0,0,0.6,1.5
ENSMUSG00000031070,MRGPRF,"MAS-related GPR, member F",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,2.6,22.7,10,0.9,3.08,2.5,22.7,22.7,0.00902,0,0,1.6,4.8
ENSMUSG00000036208,BC027231,cDNA sequence BC027231,nucleus|,negative regulation of neuron differentiation|positive regulation of Notch signaling pathway|,molecular_function|,9,-1.7,25.1,9,0,0,-1.7,22.2,-22.2,0.0106,0,0,-3,-0.8
ENSMUSG00000029647,PAN3,PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae),cytoplasmic mRNA processing body|cytoplasm|PAN complex|,"deadenylation-dependent decapping of nuclear-transcribed mRNA|mRNA processing|protein phosphorylation|protein targeting|positive regulation of cytoplasmic mRNA processing body assembly|positive regulation of cytoplasmic mRNA processing body assembly|RNA phosphodiester bond hydrolysis, exonucleolytic|","nucleotide binding|poly(A)-specific ribonuclease activity|protein kinase activity|protein binding|ATP binding|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.6,12,10,-0.7,10.1,-0.7,21.7,-21.7,0.0125,0,0,-1.1,-0.4
ENSMUSG00000027698,NCEH1,neutral cholesterol ester hydrolase 1,endoplasmic reticulum|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,protein dephosphorylation|lipid metabolic process|xenobiotic metabolic process|metabolic process|lipid catabolic process|SMAD protein signal transduction|,"phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|serine hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|phosphate ion binding|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|carboxylic ester hydrolase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-1.5,22.2,10,-0.3,0.614,-1.2,21.5,-21.5,0.0135,0,0,-2.8,-0.6
ENSMUSG00000040297,SUCO,SUN domain containing ossification factor,endoplasmic reticulum|rough endoplasmic reticulum|membrane|integral component of membrane|,ossification|multicellular organismal development|positive regulation of collagen biosynthetic process|positive regulation of osteoblast differentiation|regulation of bone remodeling|,molecular_function|,10,0.9,9.51,10,0.8,12,0.9,21.1,21.1,0.0157,0,0,0.5,1.4
ENSMUSG00000040420,CDH18,cadherin 18,plasma membrane|membrane|integral component of membrane|,cell adhesion|biological_process|,molecular_function|,10,1.6,22.5,10,0.2,0.397,1.6,20.9,20.9,0.017,0,0,0.6,3
ENSMUSG00000029544,CABP1,calcium binding protein 1,Golgi membrane|plasma membrane|,None,calcium ion binding|metal ion binding|,10,2,23.9,10,0.1,0.00633,2,20.6,20.6,0.0189,0,0,1.2,4
ENSMUSG00000040105,PPAPDC2,phosphatidic acid phosphatase type 2 domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,"catalytic activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,0.8,12.1,10,0.6,9.03,0.8,20.5,20.5,0.0196,0,0,0.5,1.2
ENSMUSG00000041570,CAMSAP2,"calmodulin regulated spectrin-associated protein family, member 2",cytoplasm|centrosome|cytoskeleton|microtubule|microtubule minus-end|,microtubule cytoskeleton organization|regulation of organelle organization|regulation of organelle organization|,protein binding|microtubule binding|microtubule minus-end binding|,10,0.5,12.3,10,1.3,14,1,20,20,0.0239,0,0,0.4,1.6
ENSMUSG00000040231,SYNGR4,synaptogyrin 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-1.8,23.2,10,0.4,1.05,-1.7,19.9,-19.9,0.0247,0,0,-3,-1
ENSMUSG00000039480,NT5DC1,5'-nucleotidase domain containing 1,cellular_component|,biological_process|,"molecular_function|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|metal ion binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,1.8,22.5,10,0,0,1.8,19.5,19.5,0.0284,0,0,0.9,3
ENSMUSG00000036890,GTDC1,glycosyltransferase-like domain containing 1,cellular_component|,biological_process|biosynthetic process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|",10,2.8,22,10,0,0,2.8,19.4,19.4,0.0293,0,0,2.3,5
ENSMUSG00000038368,FOCAD,focadhesin,focal adhesion|membrane|integral component of membrane|cell junction|,biological_process|,molecular_function|,10,1.7,22.7,10,-0.1,0.39,1.7,19.3,19.3,0.0303,0,0,0.9,3
ENSMUSG00000006010,BC003331,cDNA sequence BC003331,cellular_component|membrane|integral component of membrane|,biological_process|oxidation-reduction process|,molecular_function|zinc ion binding|oxidoreductase activity|,10,-0.7,10.5,10,-0.8,8.84,-0.8,18.9,-18.9,0.034,0,0,-1.4,-0.5
ENSMUSG00000033031,C330027C09RIK,RIKEN cDNA C330027C09 gene,cytoplasm|plasma membrane|membrane|integral component of membrane|,spermatogenesis|positive regulation of neural precursor cell proliferation|,None,10,-1.6,22,10,0.5,0.882,-1.6,18.8,-18.8,0.035,0,0,-3,-0.7
ENSMUSG00000024754,TMEM2,transmembrane protein 2,membrane|integral component of membrane|extracellular vesicular exosome|,multicellular organismal development|biological_process|,molecular_function|,10,0.7,1.83,10,-2.5,21.8,-2.5,18.3,-18.3,0.04,0,0,-5,-2
ENSMUSG00000038733,WDR26,WD repeat domain 26,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.5,6.04,10,0.8,13.8,0.7,18.2,18.2,0.0411,0,0,0.4,1.2
ENSMUSG00000042305,TMEM183A,transmembrane protein 183A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.6,21.3,10,-0.2,0.214,1.6,17.9,17.9,0.0443,0,0,0.6,3
ENSMUSG00000031608,GALNT7,UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7,Golgi apparatus|membrane|membrane|integral component of membrane|,protein O-linked glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|polypeptide N-acetylgalactosaminyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,1.6,19.7,10,-0.4,0.369,1.5,16.3,16.3,0.0485,0,0,0.4,3
ENSMUSG00000039428,TMEM135,transmembrane protein 135,peroxisome|peroxisome|membrane|integral component of membrane|,peroxisome organization|,molecular_function|,10,1.4,7.29,10,0.6,9.41,1.2,15.5,15.5,0.0493,0,0,0.3,2
ENSMUSG00000029782,TMEM209,transmembrane protein 209,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.9,6.57,10,-0.9,9.18,-0.9,15.4,-15.4,0.0495,0,0,-1.6,-0.4
ENSMUSG00000046441,CMTR2,cap methyltransferase 2,nucleus|cytoplasm|membrane|integral component of membrane|,7-methylguanosine mRNA capping|mRNA processing|methylation|cap2 mRNA methylation|,mRNA (nucleoside-2'-O-)-methyltransferase activity|methyltransferase activity|transferase activity|,10,-0.6,13.5,10,-0.5,2.59,-0.6,15.3,-15.3,0.0495,0,0,-1,-0.3
ENSMUSG00000036155,MGAT5,mannoside acetylglucosaminyltransferase 5,Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,protein N-linked glycosylation|protein N-linked glycosylation|,"acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity|",10,-0.6,8.15,10,-1.6,8.65,-0.8,15.3,-15.3,0.0495,0,0,-1.8,-0.4
ENSMUSG00000028345,TEX10,testis expressed gene 10,nucleus|cytoplasm|membrane|integral component of membrane|MLL1 complex|,biological_process|,molecular_function|,9,-1,17,9,0.4,1.83,-0.9,15.1,-15.1,0.0499,0,0,-1.7,-0.4
ENSMUSG00000027651,RPRD1B,regulation of nuclear pre-mRNA domain containing 1B,"nucleus|DNA-directed RNA polymerase II, holoenzyme|","transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|regulation of cell cycle process|positive regulation of transcription from RNA polymerase II promoter|dephosphorylation of RNA polymerase II C-terminal domain|",RNA polymerase II core binding|,10,-0.5,3.14,10,-1.1,13.8,-0.8,14.8,-14.8,0.0501,0,0,-1.9,-0.4
ENSMUSG00000033943,MGA,MAX gene associated,nucleus|transcription factor complex|MLL1 complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|sequence-specific DNA binding transcription factor activity|protein dimerization activity|,10,-0.7,8.15,10,-0.6,6.92,-0.7,14.3,-14.3,0.0505,0,0,-1.1,-0.3
ENSMUSG00000028557,RNF11,ring finger protein 11,ubiquitin ligase complex|ubiquitin ligase complex|nucleus|cytoplasm|endosome|extracellular vesicular exosome|,ubiquitin-dependent protein catabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein autoubiquitination|,ubiquitin-protein transferase activity|protein binding|zinc ion binding|metal ion binding|,10,-0.6,5.25,10,-0.7,9.44,-0.6,14.1,-14.1,0.0508,0,0,-1,-0.3
ENSMUSG00000034850,TMEM127,transmembrane protein 127,cytoplasm|plasma membrane|membrane|integral component of membrane|,negative regulation of cell proliferation|negative regulation of TOR signaling|,molecular_function|,10,0.7,9,10,0.6,5.13,0.6,13.7,13.7,0.0512,0,0,0.3,1.1
ENSMUSG00000021886,GPR65,G-protein coupled receptor 65,plasma membrane|membrane|integral component of membrane|,apoptotic process|signal transduction|G-protein coupled receptor signaling pathway|response to acidity|positive regulation of cAMP biosynthetic process|actin cytoskeleton reorganization|activation of Rho GTPase activity|positive regulation of stress fiber assembly|,signal transducer activity|G-protein coupled receptor activity|,10,0.5,7.75,10,0.8,6.94,0.6,13.3,13.3,0.0517,0,0,0.3,1.2
ENSMUSG00000046675,TMEM251,transmembrane protein 251,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,3.83,10,1.1,11,0.9,13.2,13.2,0.0519,0,0,0.5,1.6
ENSMUSG00000068015,LRCH1,leucine-rich repeats and calponin homology (CH) domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.6,10.4,10,0.5,3.19,0.6,13.2,13.2,0.0519,0,0,0.3,1.1
ENSMUSG00000045087,S1PR5,sphingosine-1-phosphate receptor 5,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|sphingosine-1-phosphate receptor activity|,10,-0.4,2.77,10,-1,11.3,-0.7,12.9,-12.9,0.0523,0,0,-1.8,-0.4
ENSMUSG00000079020,SLC45A4,"solute carrier family 45, member 4",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,-0.6,7.34,10,-0.6,5.83,-0.6,12.8,-12.8,0.0525,0,0,-1.2,-0.3
ENSMUSG00000030786,ITGAM,integrin alpha M,nucleus|integrin complex|external side of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,leukocyte migration involved in inflammatory response|cell adhesion|cell adhesion|leukocyte cell-cell adhesion|integrin-mediated signaling pathway|microglia development|single organismal cell-cell adhesion|neutrophil chemotaxis|cellular extravasation|activated T cell proliferation|,opsonin binding|opsonin binding|glycoprotein binding|heparin binding|heparan sulfate proteoglycan binding|metal ion binding|protein heterodimerization activity|,10,0.4,5.47,10,0.6,8.01,0.5,12.6,12.6,0.0529,0,0,0.2,1
ENSMUSG00000029550,SPPL3,signal peptide peptidase 3,endoplasmic reticulum|rough endoplasmic reticulum|membrane|integral component of membrane|Golgi-associated vesicle membrane|integral component of cytoplasmic side of endoplasmic reticulum membrane|integral component of lumenal side of endoplasmic reticulum membrane|,proteolysis|,"aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|protein homodimerization activity|",10,0.8,11.4,10,0.4,1.82,0.7,12.3,12.3,0.0533,0,0,0.4,1.4
ENSMUSG00000035181,HEATR5A,HEAT repeat containing 5A,cellular_component|,biological_process|,molecular_function|,10,0.7,8.16,10,0.5,4.37,0.6,11.9,11.9,0.0541,0,0,0.3,1.2
ENSMUSG00000026443,LRRN2,"leucine rich repeat protein 2, neuronal",cellular_component|,biological_process|,molecular_function|,10,1.4,14.8,10,0,0,1.4,11.7,11.7,0.0544,0,0,0.2,2.6
ENSMUSG00000033446,LPAR6,lysophosphatidic acid receptor 6,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.6,8.28,10,-0.4,3.75,-0.5,11.2,-11.2,0.0557,0,0,-1.1,-0.2
ENSMUSG00000060591,IFITM2,interferon induced transmembrane protein 2,cellular_component|plasma membrane|membrane|integral component of membrane|,immune system process|response to biotic stimulus|response to virus|response to virus|response to interferon-gamma|response to interferon-alpha|response to interferon-beta|negative regulation of viral genome replication|innate immune response|negative regulation of viral entry into host cell|negative regulation of viral entry into host cell|defense response to virus|,molecular_function|,10,0,0,10,1.1,14,1.1,11,11,0.0563,0,0,0.6,2
ENSMUSG00000075227,ZNHIT2,"zinc finger, HIT domain containing 2",None,None,metal ion binding|,6,-1.5,12.9,5,0.8,1.23,-1.4,10.9,-10.9,0.0567,0,0,-2,-0.5
ENSMUSG00000096115,FAM57A,"family with sequence similarity 57, member A",cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,7,-1,11.8,7,2,4.22,-0.9,10.9,-10.9,0.0567,0,0,-2,1.8
ENSMUSG00000047789,SLC38A9,"solute carrier family 38, member 9",cellular_component|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|amino acid transport|biological_process|,molecular_function|,10,-0.3,1.72,10,-0.6,10.3,-0.5,10.8,-10.8,0.0569,0,0,-1,-0.2
ENSMUSG00000024982,ZDHHC6,"zinc finger, DHHC domain containing 6",endoplasmic reticulum|membrane|integral component of membrane|,protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,1.4,12,10,0.2,0.701,0.5,10.2,10.2,0.0593,0,0,0.2,2.6
ENSMUSG00000037344,SLC12A9,"solute carrier family 12 (potassium/chloride transporters), member 9",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|transmembrane transport|,None,10,-0.1,0.172,10,-1.5,12.9,-1.1,10.1,-10.1,0.0598,0,0,-2.7,-0.6
ENSMUSG00000040747,CD53,CD53 antigen,immunological synapse|plasma membrane|cell-cell junction|cell surface|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,positive regulation of myoblast fusion|,None,10,-0.6,6.78,10,-0.5,3.72,-0.5,10,-10,0.0601,0,0,-1.2,-0.2
ENSMUSG00000055900,TMEM69,transmembrane protein 69,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.9,8.09,10,-0.8,2.25,-0.8,9.89,-9.89,0.0606,0,0,-1.7,-0.3
ENSMUSG00000013858,TMEM259,transmembrane protein 259,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,3.63,10,0.6,6.8,0.7,9.77,9.77,0.0611,0,0,0.3,1.4
ENSMUSG00000049092,GPR137C,G protein-coupled receptor 137C,cellular_component|,biological_process|,molecular_function|,10,0.9,6.82,10,0.6,3.63,0.7,9.68,9.68,0.0615,0,0,0.3,1.5
ENSMUSG00000049988,LRRC25,leucine rich repeat containing 25,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,3.13,10,1.2,10,1,9.56,9.56,0.0619,0,0,0.3,2.1
ENSMUSG00000021171,ESYT2,extended synaptotagmin-like protein 2,endoplasmic reticulum|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|intrinsic component of endoplasmic reticulum membrane|extrinsic component of cytoplasmic side of plasma membrane|organelle membrane contact site|,transport|lipid transport|endocytosis|biological_process|,calcium ion binding|calcium-dependent phospholipid binding|lipid binding|phosphatidylethanolamine binding|phosphatidylcholine binding|phosphatidylinositol binding|metal ion binding|,10,0.5,8.59,10,0.3,1.46,0.5,9.25,9.25,0.0634,0,0,0.2,1.1
ENSMUSG00000019943,ATP2B1,"ATPase, Ca++ transporting, plasma membrane 1",integral component of plasma membrane|cytoplasmic side of plasma membrane|membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|dendrite membrane|dendritic spine membrane|neuronal cell body membrane|membrane raft|apical part of cell|extracellular vesicular exosome|,calcium ion transport|calcium ion export|,nucleotide binding|protein binding|ATP binding|hydrolase activity|PDZ domain binding|,10,0.9,8.79,10,2,4.44,0.9,9.13,9.13,0.0642,0,0,0.4,3.1
ENSMUSG00000016494,CD34,CD34 antigen,extracellular region|cytoplasm|cytoplasm|lysosome|plasma membrane|external side of plasma membrane|external side of plasma membrane|basal plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|glomerular endothelium fenestra|intercellular bridge|perinuclear region of cytoplasm|cell periphery|,tissue homeostasis|endothelial cell proliferation|glutamate metabolic process|cell adhesion|regulation of blood pressure|negative regulation of gene expression|single organismal cell-cell adhesion|hemopoiesis|negative regulation of blood coagulation|negative regulation of tumor necrosis factor production|positive regulation of interleukin-10 production|paracrine signaling|positive regulation of odontogenesis|negative regulation of nitric oxide biosynthetic process|positive regulation of angiogenesis|leukocyte migration|hematopoietic stem cell proliferation|positive regulation of transforming growth factor beta production|positive regulation of granulocyte colony-stimulating factor production|extracellular vesicular exosome assembly|negative regulation of cellular response to heat|negative regulation of cellular response to hypoxia|negative regulation of interleukin-2 secretion|positive regulation of glial cell line-derived neurotrophic factor secretion|negative regulation of neuron death|positive regulation of vasculogenesis|,transcription factor binding|carbohydrate binding|sulfate binding|,10,-0.9,7.21,10,-0.9,1.9,-0.9,8.8,-8.8,0.0661,0,0,-1.8,-0.4
ENSMUSG00000010095,SLC3A2,"solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2",nucleus|cytoplasm|plasma membrane|membrane|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,amino acid transmembrane transport|carbohydrate metabolic process|transport|amino acid transport|neutral amino acid transport|response to exogenous dsRNA|leucine import|,double-stranded RNA binding|catalytic activity|protein binding|neutral amino acid transmembrane transporter activity|cation binding|poly(A) RNA binding|,10,-0.7,5.42,10,-0.7,3.55,-0.7,8.61,-8.61,0.0672,0,0,-1.5,-0.3
ENSMUSG00000030095,TMEM43,transmembrane protein 43,nucleus|nuclear inner membrane|integral component of nuclear inner membrane|endoplasmic reticulum|endoplasmic reticulum lumen|Golgi apparatus|membrane|integral component of membrane|,nuclear membrane organization|nuclear membrane organization|,protein self-association|,10,-1.1,11.7,10,1.1,11.1,-1.1,8.61,-8.61,0.0672,0,0,-2,1.6
ENSMUSG00000028217,CDH17,cadherin 17,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,transport|oligopeptide transport|cell adhesion|homophilic cell adhesion|calcium-dependent cell-cell adhesion|oligopeptide transmembrane transport|,proton-dependent oligopeptide secondary active transmembrane transporter activity|calcium ion binding|protein binding|metal ion binding|,10,0.5,3.94,10,0.5,4.77,0.5,8.35,8.35,0.069,0,0,0.1,1.2
ENSMUSG00000054150,SYNE3,"spectrin repeat containing, nuclear envelope family member 3",nucleus|nuclear envelope|nuclear outer membrane|endoplasmic reticulum|membrane|membrane|integral component of membrane|SUN-KASH complex|SUN-KASH complex|,cytoskeleton organization|regulation of cell shape|establishment of protein localization to membrane|cytoskeletal anchoring at nuclear membrane|,actin binding|protein binding|actin filament binding|,10,-0.8,8.3,10,-0.3,1.17,-0.7,8.24,-8.24,0.0698,0,0,-1.5,-0.2
ENSMUSG00000071652,INTS5,integrator complex subunit 5,nucleus|membrane|membrane|integral component of membrane|integrator complex|,snRNA processing|,molecular_function|,10,1,8.53,10,0.3,1.44,1,8.21,8.21,0.07,0,0,0.2,1.7
ENSMUSG00000066595,MFSD7B,major facilitator superfamily domain containing 7B,mitochondrion|plasma membrane|membrane|integral component of membrane|,blood vessel development|in utero embryonic development|transport|mitochondrial transport|heme transport|erythrocyte differentiation|erythrocyte differentiation|limb morphogenesis|multicellular organism growth|embryonic digit morphogenesis|erythrocyte maturation|regulation of organ growth|spleen development|embryonic skeletal system morphogenesis|transmembrane transport|head morphogenesis|heme export|,heme transporter activity|,7,0,0,7,1.4,10.9,1.3,8.2,8.2,0.0701,0,0,0.7,2.9
ENSMUSG00000031302,NLGN3,neuroligin 3,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|cell junction|endocytic vesicle|synapse|synapse|excitatory synapse|,"regulation of respiratory gaseous exchange by neurological system process|receptor-mediated endocytosis|cell adhesion|neuron cell-cell adhesion|synapse assembly|synapse assembly|learning|visual learning|adult behavior|social behavior|social behavior|axon extension|oligodendrocyte differentiation|regulation of synaptic transmission|synapse organization|synapse organization|positive regulation of synapse assembly|regulation of synaptic transmission, glutamatergic|positive regulation of synaptic transmission, glutamatergic|rhythmic synaptic transmission|regulation of excitatory postsynaptic membrane potential|regulation of inhibitory postsynaptic membrane potential|regulation of inhibitory postsynaptic membrane potential|regulation of dendritic spine morphogenesis|vocalization behavior|postsynaptic membrane assembly|presynaptic membrane assembly|regulation of long-term synaptic potentiation|regulation of N-methyl-D-aspartate selective glutamate receptor activity|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|regulation of terminal button organization|positive regulation of excitatory postsynaptic membrane potential|positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|",receptor activity|receptor activity|neurexin family protein binding|neurexin family protein binding|cell adhesion molecule binding|,10,0.6,6.87,10,0.3,2.16,0.6,7.93,7.93,0.0723,0,0,-0.1,1.6
ENSMUSG00000032422,SNX14,sorting nexin 14,cellular_component|membrane|integral component of membrane|,transport|protein transport|termination of G-protein coupled receptor signaling pathway|,molecular_function|phosphatidylinositol binding|,10,0.4,6.37,10,0.4,1.76,0.4,7.83,7.83,0.0732,0,0,0.1,0.9
ENSMUSG00000032122,SLC37A2,"solute carrier family 37 (glycerol-3-phosphate transporter), member 2",intracellular|cell|membrane|integral component of membrane|extracellular vesicular exosome|,glycerol-3-phosphate metabolic process|glycerophosphate shuttle|transport|carbohydrate transport|polyol transport|glycerol-3-phosphate transport|ion transmembrane transport|transmembrane transport|,transporter activity|glycerol-3-phosphate transmembrane transporter activity|,10,0.4,3.91,10,0.4,4.25,0.4,7.82,7.82,0.0733,0,0,0.1,0.9
ENSMUSG00000049103,CCR2,chemokine (C-C motif) receptor 2,plasma membrane|plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,"angiogenesis|blood vessel remodeling|wound healing involved in inflammatory response|monocyte chemotaxis|positive regulation of T-helper 1 type immune response|negative regulation of type 2 immune response|chemotaxis|inflammatory response|immune response|humoral immune response|cellular defense response|signal transduction|G-protein coupled receptor signaling pathway|regulation of vascular endothelial growth factor production|positive regulation of T cell chemotaxis|negative regulation of angiogenesis|cytokine-mediated signaling pathway|sensory perception of pain|cellular homeostasis|hemopoiesis|regulation of cell migration|positive regulation of interferon-gamma production|positive regulation of interleukin-2 production|T-helper 17 cell chemotaxis|positive regulation of tumor necrosis factor biosynthetic process|apoptotic cell clearance|negative regulation of eosinophil degranulation|positive regulation of T-helper 1 cell differentiation|positive regulation of alpha-beta T cell proliferation|positive regulation of inflammatory response|positive regulation of T cell activation|chemokine-mediated signaling pathway|positive regulation of monocyte chemotaxis|positive regulation of monocyte chemotaxis|positive regulation of immune complex clearance by monocytes and macrophages|positive regulation of monocyte extravasation|positive regulation of CD8-positive, alpha-beta T cell extravasation|positive regulation of astrocyte chemotaxis|positive regulation of hematopoietic stem cell migration|",signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|cytokine binding|chemokine (C-C motif) ligand 2 binding|chemokine (C-C motif) ligand 12 binding|chemokine (C-C motif) ligand 7 binding|,10,1.2,9.42,10,0.2,0.336,0.4,7.77,7.77,0.0737,0,0,0.2,1.9
ENSMUSG00000037958,CCDC55,coiled-coil domain containing 55,nucleus|nuclear speck|ribonucleoprotein complex|,"regulation of alternative mRNA splicing, via spliceosome|mRNA processing|nucleocytoplasmic transport|RNA splicing|developmental process|",RNA binding|mRNA binding|poly(A) RNA binding|,10,0.7,0.589,10,1,7.62,0.9,7.73,7.73,0.074,0,0,0.3,2
ENSMUSG00000048677,TPCN2,two pore segment channel 2,intracellular|cell|lysosome|lysosomal membrane|lysosomal membrane|plasma membrane|endosome membrane|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|cellular calcium ion homeostasis|smooth muscle contraction|regulation of ion transmembrane transport|release of sequestered calcium ion into cytosol|transmembrane transport|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|protein kinase binding|identical protein binding|NAADP-sensitive calcium-release channel activity|NAADP-sensitive calcium-release channel activity|NAADP-sensitive calcium-release channel activity|,10,0.7,6.01,10,0.5,2.2,0.7,7.7,7.7,0.0743,0,0,0.1,1.7
ENSMUSG00000038866,ZCCHC2,"zinc finger, CCHC domain containing 2",cytoplasm|,biological_process|,molecular_function|nucleic acid binding|zinc ion binding|phosphatidylinositol binding|metal ion binding|,10,1.1,7.8,10,0.5,2.83,1,7.7,7.7,0.0743,0,0,0.2,1.8
ENSMUSG00000020101,4632428N05RIK,RIKEN cDNA 4632428N05 gene,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,"negative regulation of T cell cytokine production|BMP signaling pathway|positive regulation of BMP signaling pathway|positive regulation of BMP signaling pathway|stem cell differentiation|negative regulation of CD4-positive, alpha-beta T cell proliferation|positive regulation of stem cell differentiation|",protein binding|,10,0.3,1.75,10,0.5,6.46,0.4,7.57,7.57,0.0756,0,0,0.1,1.1
ENSMUSG00000037242,CLIC4,chloride intracellular channel 4 (mitochondrial),intracellular|intracellular|nucleus|cytoplasm|mitochondrion|mitochondrion|vacuole|centrosome|cytosol|plasma membrane|microvillus|cell-cell junction|cell surface|microtubule cytoskeleton|membrane|integral component of membrane|nuclear matrix|midbody|cytoplasmic vesicle|chloride channel complex|apical part of cell|perinuclear region of cytoplasm|extracellular vesicular exosome|,angiogenesis|endothelial cell morphogenesis|transport|ion transport|chloride transport|vacuolar acidification|fertilization|keratinocyte differentiation|keratinocyte differentiation|negative regulation of cell migration|regulation of ion transmembrane transport|multicellular organism growth|branching morphogenesis of an epithelial tube|retina vasculature morphogenesis in camera-type eye|cellular response to calcium ion|chloride transmembrane transport|,voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|protein binding|protein complex binding|,10,0.7,5.84,10,0.5,2.39,0.6,7.45,7.45,0.0769,0,0,0.1,1.3
ENSMUSG00000022754,TMEM45A,transmembrane protein 45a,integral component of plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.854,10,0.6,7.7,0.4,7.41,7.41,0.0773,0,0,0.1,1.1
ENSMUSG00000039065,FAM173B,"family with sequence similarity 173, member B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,0.156,10,0.6,7.81,0.6,7.4,7.4,0.0774,0,0,0.1,1.1
ENSMUSG00000037190,CYB561D2,cytochrome b-561 domain containing 2,cellular_component|membrane|integral component of membrane|,transport|biological_process|oxidation-reduction process|,molecular_function|metal ion binding|,10,-0.4,2.75,10,-0.6,4.97,-0.5,7.27,-7.27,0.079,0,0,-1.2,-0.1
ENSMUSG00000048058,LDLRAD3,low density lipoprotein receptor class A domain containing 3,plasma membrane|membrane|integral component of membrane|cell junction|,receptor-mediated endocytosis|regulation of protein processing|,beta-amyloid binding|,10,0.7,6.76,10,-1.2,1.91,0.6,7.06,7.06,0.0817,0,0,-0.8,1.6
ENSMUSG00000023147,WRB,tryptophan rich basic protein,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|tail-anchored membrane protein insertion into ER membrane|,molecular_function|,8,-0.6,1.46,8,-0.7,5.97,-0.7,7.03,-7.03,0.0821,0,0,-1.8,-0.2
ENSMUSG00000045744,BRICD5,BRICHOS domain containing 5,cellular_component|,biological_process|,molecular_function|,10,0.4,3.41,10,0.5,4.12,0.4,6.99,6.99,0.0825,0,0,0.1,1.1
ENSMUSG00000029452,TMEM116,transmembrane protein 116,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.6,9.06,10,0.1,0.159,-0.6,6.95,-6.95,0.0829,0,0,-1.4,-0.1
ENSMUSG00000024679,MS4A6D,"membrane-spanning 4-domains, subfamily A, member 6D",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,0.657,10,0.7,7.03,0.6,6.93,6.93,0.0832,0,0,-0.2,1.8
ENSMUSG00000042682,SELK,selenoprotein K,endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|plasma membrane|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|response to oxidative stress|macrophage derived foam cell differentiation|protein palmitoylation|positive regulation of cell migration|positive regulation of T cell proliferation|respiratory burst after phagocytosis|regulation of protein transport|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|positive regulation of T cell migration|,molecular_function|,10,-0.5,7.61,10,-0.2,0.572,-0.4,6.88,-6.88,0.0838,0,0,-1.2,-0.1
ENSMUSG00000030748,IL4RA,"interleukin 4 receptor, alpha",extracellular region|extracellular space|plasma membrane|membrane|integral component of membrane|receptor complex|,immune system process|production of molecular mediator involved in inflammatory response|regulation of cell proliferation|defense response to protozoan|positive regulation of macrophage activation|negative regulation of T-helper 1 cell differentiation|positive regulation of T-helper 2 cell differentiation|positive regulation of chemokine secretion|,cytokine receptor activity|protein binding|,10,-0.9,5.65,10,-0.5,1.95,-0.8,6.75,-6.75,0.0855,0,0,-1.8,-0.2
ENSMUSG00000025510,CD151,CD151 antigen,membrane|integral component of membrane|,cell migration|T cell proliferation|,None,10,0.4,1.61,10,0.7,6.07,0.5,6.71,6.71,0.0862,0,0,0,1.5
ENSMUSG00000029501,ANKLE2,ankyrin repeat and LEM domain containing 2,endoplasmic reticulum|membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,cell cycle|mitotic nuclear division|mitotic nuclear envelope reassembly|positive regulation of protein dephosphorylation|negative regulation of phosphorylation|cell division|,protein phosphatase 2A binding|,10,-0.5,5.14,10,-0.7,1.99,-0.4,6.67,-6.67,0.0867,0,0,-1.4,0
ENSMUSG00000047787,FLRT1,fibronectin leucine rich transmembrane protein 1,extracellular space|membrane|integral component of membrane|,None,None,10,0.2,1.04,10,0.7,7.37,0.5,6.5,6.5,0.0895,0,0,0.1,1.4
ENSMUSG00000015966,IL17RB,interleukin 17 receptor B,extracellular region|cytoplasm|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|,cytokine-mediated signaling pathway|,cytokine receptor activity|,10,-0.8,4.76,10,-1.1,2.19,-0.8,6.49,-6.49,0.0897,0,0,-1.8,-0.2
ENSMUSG00000022564,GRINA,"glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,endoplasmic reticulum calcium ion homeostasis|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,ion channel binding|,10,-0.1,0.405,10,-0.7,8.3,-0.7,6.44,-6.44,0.0904,0,0,-1.7,-0.1
ENSMUSG00000023259,SLC26A6,"solute carrier family 26, member 6",intracellular|endoplasmic reticulum|plasma membrane|plasma membrane|integral component of plasma membrane|vesicle membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|cytoplasmic vesicle|brush border membrane|brush border membrane|membrane-bounded vesicle|chloride channel complex|intracellular membrane-bounded organelle|sperm midpiece|,transport|ion transport|anion transport|chloride transport|chloride transport|chloride transport|sulfate transport|sulfate transport|sulfate transport|bicarbonate transport|bicarbonate transport|bicarbonate transport|formate transport|formate transport|mannitol transport|oxalate transport|oxalate transport|oxalate transport|transepithelial chloride transport|transepithelial chloride transport|transepithelial chloride transport|angiotensin-activated signaling pathway|epithelial fluid transport|oxalic acid secretion|sperm capacitation|intestinal absorption|regulation of intracellular pH|regulation of intracellular pH|intracellular pH elevation|transmembrane transport|protein kinase C signaling|protein kinase C signaling|transepithelial transport|cellular response to cAMP|cellular response to fructose stimulus|cellular response to interferon-gamma|sulfate transmembrane transport|sulfate transmembrane transport|chloride transmembrane transport|chloride transmembrane transport|positive regulation of dipeptide transmembrane transport|,chloride channel activity|protein binding|secondary active sulfate transmembrane transporter activity|bicarbonate transmembrane transporter activity|bicarbonate transmembrane transporter activity|bicarbonate transmembrane transporter activity|chloride transmembrane transporter activity|chloride transmembrane transporter activity|chloride transmembrane transporter activity|sulfate transmembrane transporter activity|sulfate transmembrane transporter activity|sulfate transmembrane transporter activity|antiporter activity|anion:anion antiporter activity|anion:anion antiporter activity|anion:anion antiporter activity|formate transmembrane transporter activity|efflux transmembrane transporter activity|formate uptake transmembrane transporter activity|formate efflux transmembrane transporter activity|oxalate transmembrane transporter activity|oxalate transmembrane transporter activity|oxalate transmembrane transporter activity|PDZ domain binding|,10,1.4,9.55,10,0.1,0.0832,1.4,6.41,6.41,0.091,0,0,0.1,2.8
ENSMUSG00000046798,CLDN12,claudin 12,plasma membrane|tight junction|membrane|integral component of membrane|lateral plasma membrane|cell junction|cell periphery|,None,structural molecule activity|,10,0.7,6.9,10,0.4,0.263,0.7,6.4,6.4,0.0912,0,0,0.1,1.7
ENSMUSG00000036810,CNEP1R1,CTD nuclear envelope phosphatase 1 regulatory subunit 1,nucleus|cytoplasm|membrane|integral component of membrane|nuclear membrane|Nem1-Spo7 phosphatase complex|,lipid metabolic process|positive regulation of triglyceride biosynthetic process|protein localization to nucleus|positive regulation of protein dephosphorylation|,molecular_function|,10,0.5,8.33,10,-0.2,0.628,0.5,6.35,6.35,0.092,0,0,-0.1,1.4
ENSMUSG00000025728,PIGQ,"phosphatidylinositol glycan anchor biosynthesis, class Q",glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|membrane|integral component of membrane|,GPI anchor biosynthetic process|GPI anchor biosynthetic process|,"transferase activity|transferase activity, transferring glycosyl groups|phosphatidylinositol N-acetylglucosaminyltransferase activity|phosphatidylinositol N-acetylglucosaminyltransferase activity|",10,0.8,2.72,10,0.5,4.7,0.7,6.33,6.33,0.0924,0,0,0,1.7
ENSMUSG00000045039,MEGF8,multiple EGF-like-domains 8,nucleus|integral component of membrane|extracellular vesicular exosome|,embryonic heart tube morphogenesis|multicellular organismal development|regulation of gene expression|embryonic limb morphogenesis|BMP signaling pathway|limb morphogenesis|cell migration involved in gastrulation|embryonic skeletal system morphogenesis|positive regulation of axon extension involved in axon guidance|epiboly involved in gastrulation with mouth forming second|embryonic heart tube left/right pattern formation|left/right pattern formation|left/right pattern formation|determination of heart left/right asymmetry|determination of heart left/right asymmetry|determination of digestive tract left/right asymmetry|determination of digestive tract left/right asymmetry|craniofacial suture morphogenesis|fasciculation of sensory neuron axon|nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|,molecular_function|receptor activity|calcium ion binding|,10,0.3,1.36,10,0.6,5.72,0.5,6.28,6.28,0.0932,0,0,0.1,1.3
ENSMUSG00000028563,TM2D1,TM2 domain containing 1,integral component of plasma membrane|membrane|integral component of membrane|,apoptotic process|G-protein coupled receptor signaling pathway|apoptotic signaling pathway|,beta-amyloid binding|G-protein coupled receptor activity|,10,0.8,8.32,10,0.2,0.666,0.7,6.24,6.24,0.0938,0,0,0.1,1.5
ENSMUSG00000019437,TLCD1,TLC domain containing 1,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.8,3.71,10,-1.4,3.47,-1.2,6.18,-6.18,0.0949,0,0,-2,-0.2
ENSMUSG00000051067,LINGO3,leucine rich repeat and Ig domain containing 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.7,6.94,10,0,0,-0.7,6.17,-6.17,0.0952,0,0,-1.7,-0.1
ENSMUSG00000004948,ZP3,zona pellucida glycoprotein 3,outer acrosomal membrane|extracellular region|proteinaceous extracellular matrix|extracellular space|intracellular|cell|cytoplasm|cytoplasm|multivesicular body|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|secretory granule|extracellular matrix|extracellular matrix|perinuclear region of cytoplasm|,"positive regulation of type IV hypersensitivity|blastocyst formation|humoral immune response mediated by circulating immunoglobulin|positive regulation of leukocyte migration|positive regulation of humoral immune response|manganese ion transport|intracellular protein transport|binding of sperm to zona pellucida|binding of sperm to zona pellucida|binding of sperm to zona pellucida|binding of sperm to zona pellucida|binding of sperm to zona pellucida|positive regulation of phosphatidylinositol biosynthetic process|positive regulation of interferon-gamma production|positive regulation of interleukin-4 production|intracellular signal transduction|intracellular signal transduction|egg coat formation|positive regulation of T cell proliferation|positive regulation of protein kinase activity|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|phosphatidylinositol-mediated signaling|oocyte development|positive regulation of inflammatory response|positive regulation of protein kinase B signaling|protein kinase C signaling|calcium ion transmembrane transport|manganese ion transmembrane transport|positive regulation of calcium ion import|positive regulation of calcium ion import|positive regulation of acrosome reaction|positive regulation of acrosome reaction|negative regulation of binding of sperm to zona pellucida|positive regulation of acrosomal vesicle exocytosis|positive regulation of ovarian follicle development|positive regulation of ovarian follicle development|positive regulation of antral ovarian follicle growth|",signal transducer activity|signal transducer activity|signal transducer activity|manganese ion transmembrane transporter activity|protein binding|store-operated calcium channel activity|carbohydrate binding|acrosin binding|,10,0.5,2.74,10,0.6,3.73,0.6,6.14,6.14,0.0957,0,0,0,1.5
ENSMUSG00000021133,4933426M11RIK,RIKEN cDNA 4933426M11 gene,cellular_component|,biological_process|,molecular_function|,10,0.4,4.07,10,0.4,2.22,0.4,5.99,5.99,0.0988,0,0,0,1
ENSMUSG00000075470,ALG10B,"asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)",plasma membrane|membrane|integral component of membrane|,biological_process|,"potassium channel regulator activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|",10,0.5,5.25,10,0.4,1.06,0.5,5.99,5.99,0.0988,0,0,0.1,1.5
ENSMUSG00000074796,SLC4A11,"solute carrier family 4, sodium bicarbonate transporter-like, member 11",plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|anion transport|inorganic anion transport|bicarbonate transport|proton transport|cellular cation homeostasis|borate transmembrane transport|sodium ion transmembrane transport|fluid transport|borate transport|ion homeostasis|,transporter activity|sodium channel activity|inorganic anion exchanger activity|bicarbonate transmembrane transporter activity|hydrogen ion channel activity|symporter activity|anion:anion antiporter activity|borate transmembrane transporter activity|protein dimerization activity|,10,-0.6,3.24,10,-0.6,2.99,-0.6,5.92,-5.92,0.1,0,0,-1.5,0.4
ENSMUSG00000038055,DEXI,dexamethasone-induced transcript,cellular_component|,biological_process|,molecular_function|,10,0.3,2.1,10,0.5,4.21,0.4,5.9,5.9,0.101,0,0,0,1.3
ENSMUSG00000037960,1110007C09RIK,RIKEN cDNA 1110007C09 gene,nucleus|mitochondrion|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,biological_process|regulation of apoptotic process|,molecular_function|,10,0.5,6.35,10,0.2,0.431,0.4,5.71,5.71,0.104,0,0,0,1.3
ENSMUSG00000060131,ATP8B4,"ATPase, class I, type 8B, member 4",Golgi apparatus|plasma membrane|membrane|integral component of membrane|,biological_process|,nucleotide binding|molecular_function|ATP binding|hydrolase activity|,10,-0.8,7.76,10,0.1,0.0643,-0.5,5.68,-5.68,0.105,0,0,-1.8,-0.1
ENSMUSG00000079588,TMEM182,transmembrane protein 182,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.3,3.86,10,0.5,4,0.4,5.59,5.59,0.107,0,0,0.1,1.8
ENSMUSG00000030834,ABCC6,"ATP-binding cassette, sub-family C (CFTR/MRP), member 6",plasma membrane|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|,ATP catabolic process|transport|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,-0.4,3.26,10,-0.5,2.53,-0.4,5.49,-5.49,0.109,0,0,-1.2,0.2
ENSMUSG00000029534,ST7,suppression of tumorigenicity 7,membrane|integral component of membrane|,None,None,10,-0.1,0.124,10,-0.5,6.69,-0.5,5.45,-5.45,0.11,0,0,-1.6,0.2
ENSMUSG00000038296,GALNT18,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0.6,5.71,10,0.2,0.695,0.4,5.45,5.45,0.11,0,0,-0.1,1.3
ENSMUSG00000030284,CRELD1,cysteine-rich with EGF-like domains 1,cellular_component|membrane|integral component of membrane|,biological_process|,calcium ion binding|,9,0.5,1.92,9,-1,8.12,-0.9,5.4,-5.4,0.111,0,0,-2,0
ENSMUSG00000040283,BTNL9,butyrophilin-like 9,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,4.18,10,0.3,1.49,0.3,5.4,5.4,0.111,0,0,-0.1,1
ENSMUSG00000033147,SLC22A15,"solute carrier family 22 (organic anion/cation transporter), member 15",cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|transmembrane transport|,molecular_function|transmembrane transporter activity|,10,-0.2,0.767,10,-0.7,6.85,-0.6,5.35,-5.35,0.113,0,0,-1.6,0
ENSMUSG00000062949,ATP11C,"ATPase, class VI, type 11C",lysosomal membrane|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,pre-B cell differentiation|transport|cation transport|lipid transport|phospholipid transport|phospholipid translocation|positive regulation of B cell differentiation|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,-0.4,1.94,10,-1.2,4.13,-0.4,5.26,-5.26,0.115,0,0,-1.8,0
ENSMUSG00000057337,CHST3,carbohydrate (chondroitin 6/keratan) sulfotransferase 3,Golgi membrane|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|sulfur compound metabolic process|chondroitin sulfate biosynthetic process|chondroitin sulfate biosynthetic process|chondroitin sulfate biosynthetic process|T cell homeostasis|positive regulation of cellular component movement|,sulfotransferase activity|chondroitin 6-sulfotransferase activity|chondroitin 6-sulfotransferase activity|transferase activity|proteoglycan sulfotransferase activity|proteoglycan sulfotransferase activity|,10,0.6,3.99,10,0.3,1.69,0.5,5.21,5.21,0.116,0,0,-0.1,1.3
ENSMUSG00000060063,ALOX5AP,arachidonate 5-lipoxygenase activating protein,nucleus|nuclear envelope|nuclear envelope|endoplasmic reticulum|endoplasmic reticulum|cytosol|membrane|membrane|integral component of membrane|nuclear membrane|,leukotriene production involved in inflammatory response|positive regulation of acute inflammatory response|leukotriene metabolic process|leukotriene biosynthetic process|leukotriene biosynthetic process|leukotriene biosynthetic process|lipoxygenase pathway|oxidation-reduction process|protein homotrimerization|cellular response to calcium ion|,arachidonate 5-lipoxygenase activity|protein binding|enzyme activator activity|enzyme binding|protein homodimerization activity|protein heterodimerization activity|protein N-terminus binding|arachidonic acid binding|,10,-0.5,4.74,10,0.3,1.07,-0.5,5.09,-5.09,0.12,0,0,-1.2,0.5
ENSMUSG00000044534,ACKR2,atypical chemokine receptor 2,endosome|actin filament|plasma membrane|membrane|integral component of membrane|,receptor-mediated endocytosis|chemotaxis|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|neutrophil activation|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|scavenger receptor activity|protein binding|C-C chemokine receptor activity|C-X-C chemokine receptor activity|C-C chemokine binding|,10,0.5,4.85,10,0.3,0.498,0.5,5.07,5.07,0.121,0,0,-0.3,1.4
ENSMUSG00000079654,PRRT4,proline-rich transmembrane protein 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,1.2,5.94,0.9,5.03,5.03,0.122,0,0,0.1,2.5
ENSMUSG00000020224,LLPH,"LLP homolog, long-term synaptic facilitation (Aplysia)",cellular_component|,biological_process|,poly(A) RNA binding|,10,0.4,3.81,10,0.6,1.69,0.4,5,5,0.123,0,0,-0.4,1.3
ENSMUSG00000019787,TRDN,triadin,intracellular|cell|cytoplasm|endoplasmic reticulum|plasma membrane|junctional sarcoplasmic reticulum membrane|membrane|sarcoplasmic reticulum|junctional membrane complex|calcium channel complex|intracellular membrane-bounded organelle|,cellular calcium ion homeostasis|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|cytoplasmic microtubule organization|negative regulation of release of sequestered calcium ion into cytosol|positive regulation of release of sequestered calcium ion into cytosol|heart contraction|heart contraction|endoplasmic reticulum membrane organization|,None,10,0.6,5.49,10,-0.1,0.0746,0.6,4.94,4.94,0.125,0,0,-0.1,1.6
ENSMUSG00000026814,ENG,endoglin,extracellular space|nucleus|cytoplasm|external side of plasma membrane|cell surface|membrane|integral component of membrane|endothelial microparticle|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|patterning of blood vessels|vasculogenesis|vasculogenesis|response to hypoxia|positive regulation of protein phosphorylation|negative regulation of endothelial cell proliferation|heart looping|positive regulation of systemic arterial blood pressure|cell migration involved in endocardial cushion formation|regulation of transcription, DNA-templated|protein phosphorylation|cell adhesion|transmembrane receptor protein serine/threonine kinase signaling pathway|transforming growth factor beta receptor signaling pathway|heart development|positive regulation of gene expression|positive regulation of pathway-restricted SMAD protein phosphorylation|cell migration|regulation of transforming growth factor beta receptor signaling pathway|regulation of transforming growth factor beta receptor signaling pathway|central nervous system vasculogenesis|extracellular matrix disassembly|negative regulation of cell migration|positive regulation of BMP signaling pathway|negative regulation of protein autophosphorylation|positive regulation of collagen biosynthetic process|intracellular signal transduction|wound healing|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|smooth muscle tissue development|artery morphogenesis|venous blood vessel morphogenesis|cell motility|negative regulation of nitric-oxide synthase activity|cell chemotaxis|negative regulation of pathway-restricted SMAD protein phosphorylation|extracellular matrix constituent secretion|detection of hypoxia|","transforming growth factor beta-activated receptor activity|transforming growth factor beta receptor, cytoplasmic mediator activity|type II transforming growth factor beta receptor binding|protein binding|galactose binding|glycosaminoglycan binding|type I transforming growth factor beta receptor binding|protein homodimerization activity|protein homodimerization activity|transforming growth factor beta binding|transforming growth factor beta binding|",10,-0.5,1.37,10,-0.5,3.82,-0.5,4.93,-4.93,0.125,0,0,-1.5,0
ENSMUSG00000053929,CYHR1,cysteine and histidine rich 1,nuclear envelope|cytoplasm|,biological_process|,protein binding|zinc ion binding|metal ion binding|,10,0.9,4.65,10,0.4,1.36,0.9,4.89,4.89,0.126,0,0,-0.2,1.8
ENSMUSG00000066324,IMPAD1,inositol monophosphatase domain containing 1,Golgi apparatus|membrane|membrane|integral component of membrane|,skeletal system development|endochondral ossification|chondrocyte development|post-embryonic development|dephosphorylation|chondroitin sulfate metabolic process|embryonic digit morphogenesis|phosphatidylinositol phosphorylation|,"3'-nucleotidase activity|3'(2'),5'-bisphosphate nucleotidase activity|inositol monophosphate 1-phosphatase activity|hydrolase activity|metal ion binding|inositol monophosphate 3-phosphatase activity|inositol monophosphate 4-phosphatase activity|inositol monophosphate phosphatase activity|",10,0.4,1.96,10,0.4,3.2,0.4,4.88,4.88,0.127,0,0,-0.1,1.2
ENSMUSG00000038403,HFE2,hemochromatosis type 2 (juvenile) (human homolog),extracellular space|plasma membrane|cell surface|membrane|basolateral plasma membrane|anchored component of membrane|,BMP signaling pathway|BMP signaling pathway|positive regulation of transcription from RNA polymerase II promoter|iron ion homeostasis|iron ion homeostasis|,protein binding|coreceptor activity|,9,-1,7.09,9,0.1,0.0997,-0.9,4.86,-4.86,0.127,0,0,-2,-0.1
ENSMUSG00000034947,TMEM106A,transmembrane protein 106A,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.5,3.34,10,0.4,1.82,0.4,4.86,4.86,0.127,0,0,-0.7,1.3
ENSMUSG00000029416,SLC15A4,"solute carrier family 15, member 4",membrane|integral component of membrane|,transport|drug transmembrane transport|oligopeptide transport|protein transport|histidine transport|peptide transport|L-alpha-amino acid transmembrane transport|,transporter activity|L-histidine transmembrane transporter activity|symporter activity|,10,-0.6,4.95,10,-0.2,0.895,-0.3,4.8,-4.8,0.129,0,0,-1.2,0.1
ENSMUSG00000036552,ERMARD,ER membrane associated RNA degradation,cellular_component|,biological_process|,molecular_function|,10,0.4,0.938,10,0.6,4.42,0.5,4.77,4.77,0.13,0,0,-0.2,1.6
ENSMUSG00000040164,KCNS1,"K+ voltage-gated channel, subfamily S, 1",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|potassium channel regulator activity|,10,-0.6,6.06,10,0.3,0.541,-0.5,4.7,-4.7,0.133,0,0,-1.6,0.4
ENSMUSG00000029669,TSPAN12,tetraspanin 12,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,angiogenesis|cell surface receptor signaling pathway|retina layer formation|regulation of angiogenesis|,None,10,-1.4,7.87,10,0.1,0.0689,-1.4,4.64,-4.64,0.135,0,0,-2,0.4
ENSMUSG00000009291,PTTG1IP,pituitary tumor-transforming 1 interacting protein,nucleus|cytoplasm|plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,protein import into nucleus|multicellular organismal development|,molecular_function|receptor activity|,10,-1,6.72,10,-0.1,0.102,-0.7,4.63,-4.63,0.135,0,0,-1.9,-0.1
ENSMUSG00000021254,GPATCH2L,G patch domain containing 2 like,cellular_component|,biological_process|,molecular_function|,10,0.7,5.88,9,0.1,0.0398,0.6,4.62,4.62,0.136,0,0,-0.1,1.7
ENSMUSG00000019838,SLC16A10,"solute carrier family 16 (monocarboxylic acid transporters), member 10",plasma membrane|membrane|integral component of membrane|,transport|transmembrane transport|,None,10,0.4,5.98,10,0,0,0.4,4.6,4.6,0.136,0,0,-0.1,1.3
ENSMUSG00000022385,GTSE1,G two S phase expressed protein 1,cytoplasm|cytoskeleton|microtubule|membrane|,None,None,8,-1.1,4.39,9,0.7,5.25,0.6,4.56,4.56,0.138,0,0,-1.7,1.6
ENSMUSG00000026614,SLC30A10,"solute carrier family 30, member 10",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|zinc ion transport|biological_process|transmembrane transport|,molecular_function|cation transmembrane transporter activity|,10,0.1,0.00423,10,0.6,6.49,0.5,4.53,4.53,0.139,0,0,-0.2,1.8
ENSMUSG00000032718,MANSC1,MANSC domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.7,4.75,10,-0.2,0.696,-0.6,4.52,-4.52,0.139,0,0,-1.7,0.4
ENSMUSG00000030126,TMCC1,transmembrane and coiled coil domains 1,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.82,10,0.5,3.13,0.4,4.51,4.51,0.14,0,0,-0.1,1.3
ENSMUSG00000041949,TANGO6,transport and golgi organization 6,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,8,0.8,6.71,8,0.1,0.0881,0.8,4.46,4.46,0.142,0,0,0,2
ENSMUSG00000031170,SLC38A5,"solute carrier family 38, member 5",plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|neutral amino acid transport|glycine transport|L-alpha-amino acid transmembrane transport|,amino acid transmembrane transporter activity|neutral amino acid transmembrane transporter activity|glycine transmembrane transporter activity|,10,0.4,1.53,10,0.5,3.24,0.5,4.45,4.45,0.142,0,0,-0.1,1.5
ENSMUSG00000057654,OLFR328,olfactory receptor 328,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,1.1,5.11,9,0.2,0.685,0.3,4.43,4.43,0.143,0,0,0,1.9
ENSMUSG00000047021,CCDC108,coiled-coil domain containing 108,cellular_component|membrane|integral component of membrane|,biological_process|,poly(A) RNA binding|,10,0.6,2.18,10,0.5,2.57,0.6,4.41,4.41,0.144,0,0,-0.4,1.6
ENSMUSG00000037336,MFSD2B,major facilitator superfamily domain containing 2B,cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0.7,6.07,10,-0.3,0.272,0.6,4.4,4.4,0.144,0,0,-0.3,1.7
ENSMUSG00000048174,TMEM81,transmembrane protein 81,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,1.16,10,0.7,3.91,0.6,4.4,4.4,0.144,0,0,-0.5,1.6
ENSMUSG00000054874,PCNXL3,pecanex-like 3 (Drosophila),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.5,1.83,10,0.4,2.92,0.4,4.37,4.37,0.145,0,0,-0.1,1.4
ENSMUSG00000037106,FER1L6,fer-1-like 6 (C. elegans),cellular_component|,biological_process|,molecular_function|,9,0.1,0.276,9,0.7,5.75,0.4,4.33,4.33,0.147,0,0,-0.2,1.7
ENSMUSG00000040234,TM7SF3,transmembrane 7 superfamily member 3,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.9,6.26,10,-0.2,0.31,-0.8,4.32,-4.32,0.147,0,0,-1.9,-0.1
ENSMUSG00000058807,OLFR331,olfactory receptor 331,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.8,2.53,10,-1.2,2.35,-1.1,4.3,-4.3,0.148,0,0,-2,0.6
ENSMUSG00000030703,GDPD3,glycerophosphodiester phosphodiesterase domain containing 3,membrane|integral component of membrane|extracellular vesicular exosome|,glycerol metabolic process|lipid metabolic process|,nuclease activity|phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0.5,2.63,10,0.4,2,0.5,4.27,4.27,0.149,0,0,-0.4,1.6
ENSMUSG00000061165,OLFR160,olfactory receptor 160,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|axon guidance|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.7,1.46,10,-0.8,3.04,-0.8,4.17,-4.17,0.154,0,0,-1.8,0.7
ENSMUSG00000061928,DSG1B,desmoglein 1 beta,plasma membrane|cell-cell junction|cytoplasmic side of plasma membrane|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|cell junction|desmosome|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|,calcium ion binding|gamma-catenin binding|metal ion binding|,10,0.4,2.95,10,0.4,1.42,0.4,4.12,4.12,0.156,0,0,-0.8,1.3
ENSMUSG00000030471,ZDHHC13,"zinc finger, DHHC domain containing 13",Golgi membrane|endoplasmic reticulum|Golgi apparatus|membrane|membrane|integral component of membrane|Golgi-associated vesicle membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|,transport|ion transport|signal transduction|magnesium ion transport|ion transmembrane transport|positive regulation of I-kappaB kinase/NF-kappaB signaling|,"signal transducer activity|zinc ion binding|magnesium ion transmembrane transporter activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.5,0.686,10,0.7,3.84,0.6,4.09,4.09,0.158,0,0,-0.1,1.6
ENSMUSG00000031703,ITFG1,integrin alpha FG-GAP repeat containing 1,cellular_component|extracellular region|membrane|integral component of membrane|,biological_process|,protein binding|,10,-0.5,4.88,10,0,0,-0.4,4.05,-4.05,0.159,0,0,-1.5,0.1
ENSMUSG00000043831,LYSMD4,"LysM, putative peptidoglycan-binding, domain containing 4",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.7,2.7,10,0.7,4.69,0.7,4.02,4.02,0.161,0,0,-1.4,1.6
ENSMUSG00000019737,SYNE4,"spectrin repeat containing, nuclear envelope family member 4",nucleus|membrane|integral component of membrane|integral component of nuclear outer membrane|,establishment of epithelial cell apical/basal polarity|,actin binding|protein binding|,9,-0.5,2.96,9,-0.2,1.31,-0.5,3.99,-3.99,0.162,0,0,-1.6,0.2
ENSMUSG00000034075,ZDHHC5,"zinc finger, DHHC domain containing 5",plasma membrane|plasma membrane|membrane|membrane|integral component of membrane|dendrite|,protein palmitoylation|protein palmitoylation|protein palmitoylation|,"protein binding|zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.3,1.21,9,0.4,3.06,0.4,3.98,3.98,0.163,0,0,-0.4,1.3
ENSMUSG00000046079,LRRC8D,leucine rich repeat containing 8D,endoplasmic reticulum|plasma membrane|membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,-0.2,0.926,10,-0.5,3.71,-0.4,3.97,-3.97,0.163,0,0,-1.3,0.2
ENSMUSG00000024331,DSC2,desmocollin 2,plasma membrane|cell-cell adherens junction|intercalated disc|membrane|integral component of membrane|cell junction|desmosome|desmosome|cytoplasmic vesicle|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|cellular response to starvation|ventricular cardiac muscle cell action potential|cardiac muscle cell-cardiac muscle cell adhesion|bundle of His cell to Purkinje myocyte communication|regulation of heart rate by cardiac conduction|,calcium ion binding|metal ion binding|,10,-0.7,2.75,10,-0.6,1.48,-0.6,3.96,-3.96,0.163,0,0,-1.7,0.4
ENSMUSG00000037822,SMIM14,small integral membrane protein 14,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,5.58,10,0.1,0.186,0.6,3.96,3.96,0.163,0,0,-0.3,1.7
ENSMUSG00000024410,3110002H16RIK,RIKEN cDNA 3110002H16 gene,lysosomal membrane|,None,None,10,-0.2,0.366,10,0.7,4.64,0.7,3.92,3.92,0.165,0,0,-0.4,1.7
ENSMUSG00000070806,ZMYND12,"zinc finger, MYND domain containing 12",intracellular|,biological_process|,molecular_function|,10,0.2,0.43,10,0.5,4.23,0.4,3.91,3.91,0.166,0,0,-0.3,1.6
ENSMUSG00000067365,TMEM128,transmembrane protein 128,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.71,10,0.4,2.56,0.3,3.89,3.89,0.167,0,0,-0.3,1.4
ENSMUSG00000035595,1600002K03RIK,RIKEN cDNA 1600002K03 gene,extracellular region|cytoplasm|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,4.18,10,0.1,0.247,0.4,3.85,3.85,0.169,0,0,-0.3,1.5
ENSMUSG00000036368,RMDN2,regulator of microtubule dynamics 2,cytoplasm|mitochondrion|cytoskeleton|microtubule|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.3,6.94,10,0,0,1.2,3.85,3.85,0.169,0,0,0.1,2
ENSMUSG00000004558,NDRG2,N-myc downstream regulated gene 2,nucleus|nucleus|cytoplasm|cytoplasm|Golgi apparatus|centrosome|microtubule organizing center|cell projection|extracellular vesicular exosome|,negative regulation of cytokine production|signal transduction|multicellular organismal development|nervous system development|regulation of vascular endothelial growth factor production|Wnt signaling pathway|cell differentiation|negative regulation of smooth muscle cell proliferation|negative regulation of ERK1 and ERK2 cascade|regulation of platelet-derived growth factor production|,None,10,-0.4,3.04,10,-0.2,1.53,-0.3,3.84,-3.84,0.169,0,0,-1.5,0.2
ENSMUSG00000047898,CCR4,chemokine (C-C motif) receptor 4,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|neuronal cell body|,neuron migration|tolerance induction|chemotaxis|inflammatory response|immune response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of positive chemotaxis|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|C-C chemokine receptor activity|,10,-0.4,1.01,10,-0.4,3.01,-0.4,3.8,-3.8,0.171,0,0,-1.3,0.7
ENSMUSG00000036902,NETO2,neuropilin (NRP) and tolloid (TLL)-like 2,plasma membrane|postsynaptic density|membrane|integral component of membrane|kainate selective glutamate receptor complex|synapse|,regulation of kainate selective glutamate receptor activity|,ionotropic glutamate receptor binding|,10,0.1,0.0586,10,-0.8,6.53,-0.7,3.78,-3.78,0.172,0,0,-2,0
ENSMUSG00000026627,TMEM206,transmembrane protein 206,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,2.83,10,0.9,1.71,0.4,3.78,3.78,0.172,0,0,-0.5,1.7
ENSMUSG00000059279,OLFR224,olfactory receptor 224,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.6,4.2,10,-0.7,2.23,-0.6,3.71,-3.71,0.176,0,0,-1.6,1.1
ENSMUSG00000026566,MPZL1,myelin protein zero-like 1,membrane|integral component of membrane|,None,None,10,-0.1,0.2,10,-0.4,4.62,-0.4,3.69,-3.69,0.177,0,0,-1.4,0.9
ENSMUSG00000022462,SLC38A2,"solute carrier family 38, member 2",plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|ion transport|sodium ion transport|amino acid transport|,amino acid transmembrane transporter activity|symporter activity|,9,0.6,3.92,9,1.2,0.55,0.7,3.66,3.66,0.179,0,0,-0.1,1.9
ENSMUSG00000024011,PI16,peptidase inhibitor 16,extracellular region|extracellular space|membrane|integral component of membrane|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of cell growth involved in cardiac muscle cell development|negative regulation of cell growth involved in cardiac muscle cell development|,peptidase inhibitor activity|,10,0.4,2.6,10,0.3,1.35,0.3,3.65,3.65,0.179,0,0,-0.4,1.5
ENSMUSG00000037824,TSPAN14,tetraspanin 14,plasma membrane|cell surface|membrane|integral component of membrane|tetraspanin-enriched microdomain|,positive regulation of Notch signaling pathway|protein maturation|protein maturation|establishment of protein localization to plasma membrane|,enzyme binding|enzyme binding|,10,0.6,4.52,10,0.1,0.149,0.3,3.63,3.63,0.18,0,0,-0.1,1.6
ENSMUSG00000027770,DHX36,DEAH (Asp-Glu-Ala-His) box polypeptide 36,"chromosome, telomeric region|nucleus|chromosome|cytoplasm|","ossification|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|response to virus|RNA secondary structure unwinding|positive regulation of telomere maintenance|response to exogenous dsRNA|positive regulation of transcription from RNA polymerase II promoter|",nucleotide binding|core promoter binding|G-quadruplex RNA binding|nucleic acid binding|DNA binding|RNA binding|double-stranded RNA binding|double-stranded RNA binding|helicase activity|protein binding|ATP binding|ATP-dependent helicase activity|DNA-dependent ATPase activity|hydrolase activity|histone deacetylase binding|transcription regulatory region DNA binding|poly(A) RNA binding|G-quadruplex DNA binding|,10,0.2,0.695,9,0.6,4.01,0.7,3.61,3.61,0.182,0,0,-1.1,1.8
ENSMUSG00000021000,CTAGE5,"CTAGE family, member 5",membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,4.95,10,-0.5,5.4,-0.4,3.6,-3.6,0.182,0,0,-1.2,1.4
ENSMUSG00000028865,CD164L2,CD164 sialomucin-like 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,3.42,10,1.3,1.49,-0.3,3.6,-3.6,0.182,0,0,-1.2,1.6
ENSMUSG00000030452,NIPA2,non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human),endosome|early endosome|plasma membrane|membrane|integral component of membrane|,transport|ion transport|magnesium ion transport|,protein binding|magnesium ion transmembrane transporter activity|,10,0.5,4.82,10,-0.1,0.0181,0.4,3.53,3.53,0.186,0,0,-0.9,1.5
ENSMUSG00000052187,HBB-Y,"hemoglobin Y, beta-like embryonic chain",hemoglobin complex|blood microparticle|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transport|oxygen transport|protein heterooligomerization|,oxygen transporter activity|iron ion binding|oxygen binding|heme binding|hemoglobin alpha binding|metal ion binding|,10,0.6,0.749,10,0.5,3,0.5,3.53,3.53,0.186,0,0,-0.2,1.6
ENSMUSG00000049411,TMEM241,transmembrane protein 241,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-1.1,1.72,10,-0.8,2.11,-0.8,3.49,-3.49,0.189,0,0,-2,0.3
ENSMUSG00000034612,CHST11,carbohydrate sulfotransferase 11,Golgi apparatus|membrane|membrane|integral component of membrane|,chondrocyte development|carbohydrate metabolic process|respiratory gaseous exchange|post-embryonic development|carbohydrate biosynthetic process|chondroitin sulfate metabolic process|chondroitin sulfate biosynthetic process|chondroitin sulfate biosynthetic process|chondroitin sulfate biosynthetic process|embryonic limb morphogenesis|negative regulation of transforming growth factor beta receptor signaling pathway|polysaccharide localization|post-anal tail morphogenesis|regulation of cell proliferation|embryonic digit morphogenesis|negative regulation of apoptotic process|developmental growth|embryonic viscerocranium morphogenesis|embryonic skeletal system morphogenesis|cartilage development|,N-acetylgalactosamine 4-O-sulfotransferase activity|sulfotransferase activity|transferase activity|chondroitin 4-sulfotransferase activity|N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity|,10,0.5,2.41,10,1.3,2.04,0.5,3.47,3.47,0.19,0,0,-0.1,1.8
ENSMUSG00000030406,GIPR,gastric inhibitory polypeptide receptor,plasma membrane|membrane|integral component of membrane|,desensitization of G-protein coupled receptor protein signaling pathway|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|positive regulation of cAMP biosynthetic process|endocrine pancreas development|positive regulation of insulin secretion|gastric inhibitory peptide signaling pathway|response to calcium ion|,signal transducer activity|receptor activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|gastric inhibitory peptide receptor activity|peptide hormone binding|,10,-0.8,4.29,10,1.1,6.42,0.9,3.42,3.42,0.193,0,0,-1.2,2
ENSMUSG00000041329,ATP1B2,"ATPase, Na+/K+ transporting, beta 2 polypeptide",cytoplasm|plasma membrane|sodium:potassium-exchanging ATPase complex|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|,ATP catabolic process|transport|ion transport|potassium ion transport|sodium ion transport|cell adhesion|sodium ion transmembrane transport|potassium ion transmembrane transport|,sodium:potassium-exchanging ATPase activity|,10,-0.2,0.321,10,-0.6,4.59,-0.6,3.4,-3.4,0.195,0,0,-1.7,0.2
ENSMUSG00000040592,CD79B,CD79B antigen,nucleus|cytoplasm|Golgi apparatus|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|B cell receptor complex|extracellular vesicular exosome|,immune system process|cell surface receptor signaling pathway|B cell receptor signaling pathway|,transmembrane signaling receptor activity|protein binding|,10,0,0,10,0.6,4.2,0.5,3.37,3.37,0.197,0,0,-0.3,1.6
ENSMUSG00000051232,TMEM199,transmembrane protein 199,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.929,10,0.4,3.06,0.3,3.36,3.36,0.197,0,0,-0.4,1.4
ENSMUSG00000053559,SMAGP,small cell adhesion glycoprotein,nucleus|plasma membrane|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|,biological_process|,molecular_function|,9,-0.2,0.391,9,0.6,4.59,0.6,3.34,3.34,0.198,0,0,-0.7,1.6
ENSMUSG00000019295,TMEM129,transmembrane protein 129,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.88,10,-0.6,2.02,-0.5,3.29,-3.29,0.202,0,0,-1.7,0.4
ENSMUSG00000036813,ENTPD8,ectonucleoside triphosphate diphosphohydrolase 8,plasma membrane|membrane|integral component of membrane|,nucleoside monophosphate biosynthetic process|nucleoside diphosphate biosynthetic process|,nucleotide binding|ATP binding|hydrolase activity|nucleoside-diphosphatase activity|nucleoside-triphosphatase activity|metal ion binding|,10,0.4,3.35,10,0.2,0.584,0.4,3.27,3.27,0.203,0,0,-1.3,1.3
ENSMUSG00000050212,EVA1B,eva-1 homolog B (C. elegans),cellular_component|membrane|integral component of membrane|,biological_process|,protein binding|,10,0.2,2.49,10,0.8,2.23,0.3,3.24,3.24,0.205,0,0,-0.4,1.7
ENSMUSG00000025239,LIMD1,LIM domains containing 1,cytoplasmic mRNA processing body|nucleus|cytoplasm|cytoplasm|adherens junction|focal adhesion|RISC complex|cell junction|,"response to hypoxia|osteoblast development|transcription, DNA-templated|regulation of transcription, DNA-templated|cytoskeleton organization|regulation of cell shape|phosphorylation|cell migration|gene silencing by RNA|cytoplasmic mRNA processing body assembly|gene silencing by miRNA|negative regulation of hippo signaling|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|negative regulation of canonical Wnt signaling pathway|positive regulation of gene silencing by miRNA|regulation of RNA biosynthetic process|",transcription corepressor activity|protein binding|zinc ion binding|metal ion binding|,10,0.3,1.99,10,0.3,1.45,0.3,3.23,3.23,0.206,0,0,-0.6,1.4
ENSMUSG00000026223,ITM2C,integral membrane protein 2C,lysosome|lysosome|Golgi apparatus|plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,negative regulation of neuron projection development|neuron differentiation|positive regulation of extrinsic apoptotic signaling pathway|,beta-amyloid binding|ATP binding|,10,0.1,0.464,10,0.5,3.85,0.3,3.22,3.22,0.206,0,0,-0.5,1.4
ENSMUSG00000025165,SECTM1A,secreted and transmembrane 1A,extracellular region|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|,10,-0.1,0.141,10,-1.6,5.94,-1.6,3.17,-3.17,0.21,0,0,-3,0
ENSMUSG00000037400,ATP11B,"ATPase, class VI, type 11B",endoplasmic reticulum|membrane|membrane|integral component of membrane|recycling endosome|,biological_process|,nucleotide binding|ATP binding|hydrolase activity|,10,-0.2,0.572,10,-0.6,3.85,-0.5,3.15,-3.15,0.211,0,0,-1.7,0.4
ENSMUSG00000040412,5330417C22RIK,RIKEN cDNA 5330417C22 gene,lysosome|endosome|late endosome|Golgi apparatus|trans-Golgi network|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,autophagy|cellular response to starvation|macroautophagy|positive regulation of vacuole organization|positive regulation of autophagic vacuole assembly|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,poly(A) RNA binding|,10,-0.1,0.203,9,0.6,5.21,0.5,3.15,3.15,0.211,0,0,-0.4,1.7
ENSMUSG00000022758,P2RX6,"purinergic receptor P2X, ligand-gated ion channel, 6",integral component of nuclear inner membrane|cytoplasm|integral component of plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|neuronal cell body|dendritic spine|,transport|ion transport|cation transport|cation transport|ion transmembrane transport|ion transmembrane transport|purinergic nucleotide receptor signaling pathway|protein homooligomerization|protein heterooligomerization|,purinergic nucleotide receptor activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|ion channel activity|ATP binding|identical protein binding|,10,-0.5,4.3,10,0.3,0.233,-0.5,3.15,-3.15,0.211,0,0,-1.6,0.9
ENSMUSG00000001082,MFSD10,major facilitator superfamily domain containing 10,membrane|integral component of membrane|,transport|apoptotic process|transmembrane transport|,transporter activity|,10,-0.7,5.14,10,0.1,0.178,-0.6,3.13,-3.13,0.213,0,0,-1.8,0.3
ENSMUSG00000039270,MEGF9,multiple EGF-like-domains 9,membrane|integral component of membrane|,None,None,10,-0.3,0.867,10,-0.7,3.56,-0.4,3.09,-3.09,0.216,0,0,-1.8,0.4
ENSMUSG00000053216,BTN2A2,"butyrophilin, subfamily 2, member A2",cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,negative regulation of phosphatidylinositol 3-kinase signaling|negative regulation of cellular metabolic process|positive regulation of regulatory T cell differentiation|negative regulation of activated T cell proliferation|negative regulation of cytokine secretion|negative regulation of T cell receptor signaling pathway|negative regulation of protein kinase B signaling|negative regulation of ERK1 and ERK2 cascade|negative regulation of G1/S transition of mitotic cell cycle|,molecular_function|,10,0.5,3.38,10,0,0,0.5,3.07,3.07,0.217,0,0,-0.2,1.7
ENSMUSG00000005465,IL27RA,"interleukin 27 receptor, alpha",membrane|integral component of membrane|,positive regulation of T-helper 1 type immune response|negative regulation of type 2 immune response|positive regulation of interferon-gamma production|regulation of isotype switching to IgG isotypes|defense response to Gram-positive bacterium|interleukin-27-mediated signaling pathway|,protein binding|interleukin-27 receptor activity|,10,-0.4,1.77,10,-0.6,1.96,-0.5,3.05,-3.05,0.219,0,0,-2,0.6
ENSMUSG00000019806,AIG1,androgen-induced 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.82,10,-0.5,1.5,-0.5,3.01,-3.01,0.222,0,0,-1.8,0.5
ENSMUSG00000059149,MFSD4,major facilitator superfamily domain containing 4,cellular_component|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0.4,4.33,10,0,0,0.4,3.01,3.01,0.222,0,0,-0.3,1.6
ENSMUSG00000070733,FRYL,furry homolog-like (Drosophila),cellular_component|,biological_process|,protein binding|,10,0.5,5.25,10,-0.1,0.0596,0.5,2.98,2.98,0.224,0,0,-0.4,1.6
ENSMUSG00000028121,BCAR3,breast cancer anti-estrogen resistance 3,None,lens morphogenesis in camera-type eye|signal transduction|small GTPase mediated signal transduction|positive regulation of peptidyl-serine phosphorylation|,guanyl-nucleotide exchange factor activity|,10,-0.5,2.09,10,-0.6,1.09,-0.5,2.96,-2.96,0.225,0,0,-1.8,0.5
ENSMUSG00000041623,D11WSU47E,"DNA segment, Chr 11, Wayne State University 47, expressed",membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.2,0.926,10,-0.7,5.34,-0.7,2.93,-2.93,0.228,0,0,-1.9,0.7
ENSMUSG00000047989,INO80C,INO80 complex subunit C,nucleus|nucleolus|Ino80 complex|MLL1 complex|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|biological_process|",molecular_function|,10,-0.5,4.19,10,0,0,-0.4,2.92,-2.92,0.229,0,0,-1.6,0.4
ENSMUSG00000043067,DPY19L1,dpy-19-like 1 (C. elegans),membrane|membrane|integral component of membrane|,biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.4,1.53,10,0.4,1.58,0.4,2.9,2.9,0.23,0,0,-0.3,1.6
ENSMUSG00000028435,AQP3,aquaporin 3,cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|cell-cell junction|cell-cell junction|membrane|integral component of membrane|basolateral plasma membrane|,positive regulation of immune system process|transport|water transport|water transport|water transport|water transport|glycerol transport|glycerol transport|urea transport|response to retinoic acid|carbohydrate transmembrane transport|transmembrane transport|renal water absorption|renal water absorption|,transporter activity|water channel activity|water channel activity|glycerol channel activity|,9,-0.3,1.05,10,-0.5,2.1,-0.5,2.89,-2.89,0.231,0,0,-1.6,0.4
ENSMUSG00000048503,TMEM136,transmembrane protein 136,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,2.26,10,0.3,0.83,0.4,2.89,2.89,0.231,0,0,-1,1.4
ENSMUSG00000038973,CLDND2,claudin domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.5,2.91,10,-0.3,0.649,-0.4,2.88,-2.88,0.232,0,0,-1.6,0.8
ENSMUSG00000071068,TREML2,triggering receptor expressed on myeloid cells-like 2,plasma membrane|cell surface|membrane|integral component of membrane|,T cell activation|,receptor activity|,10,0.4,1.73,10,0.3,1.35,0.3,2.87,2.87,0.233,0,0,-0.5,1.5
ENSMUSG00000010721,LMBR1,limb region 1,membrane|integral component of membrane|,embryonic hindlimb morphogenesis|embryonic digit morphogenesis|,None,10,0.2,0.976,10,0.5,2.8,0.3,2.84,2.84,0.235,0,0,-1.4,1.3
ENSMUSG00000025425,ST8SIA5,"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,protein glycosylation|sialylation|,"alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity|sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.8,4.69,10,0,0,-0.5,2.83,-2.83,0.236,0,0,-1.9,0.4
ENSMUSG00000041594,TMTC4,transmembrane and tetratricopeptide repeat containing 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,4.98,10,-1.1,2.7,0.6,2.83,2.83,0.236,0,0,-1.5,1.7
ENSMUSG00000001964,EMD,emerin,nucleus|nuclear envelope|nuclear envelope|nuclear inner membrane|nuclear outer membrane|nuclear lamina|endoplasmic reticulum|spindle|microtubule|membrane|membrane|integral component of membrane|nuclear membrane|,negative regulation of catenin import into nucleus|skeletal muscle cell differentiation|skeletal muscle cell differentiation|positive regulation of protein export from nucleus|negative regulation of fibroblast proliferation|regulation of canonical Wnt signaling pathway|cellular response to growth factor stimulus|,actin binding|protein binding|beta-tubulin binding|,10,-0.6,4.91,10,0.3,0.948,-0.4,2.82,-2.82,0.236,0,0,-1.7,0.6
ENSMUSG00000093865,LRIT3,"leucine-rich repeat, immunoglobulin-like and transmembrane domains 3",cellular_component|,regulation of fibroblast growth factor receptor signaling pathway|,molecular_function|,10,0.4,0.75,10,-0.4,3.54,-0.3,2.77,-2.77,0.241,0,0,-1.3,1
ENSMUSG00000027351,SPRED1,"sprouty protein with EVH-1 domain 1, related sequence",nucleus|cytoplasm|plasma membrane|membrane|,"inactivation of MAPK activity|multicellular organismal development|regulation of signal transduction|negative regulation of peptidyl-threonine phosphorylation|negative regulation of peptidyl-threonine phosphorylation|negative regulation of phosphatase activity|positive regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of protein serine/threonine kinase activity|regulation of protein deacetylation|",stem cell factor receptor binding|protein binding|protein kinase binding|protein kinase binding|phosphatase binding|protein serine/threonine kinase inhibitor activity|,10,0.2,1.52,10,0.3,1.62,0.3,2.77,2.77,0.241,0,0,-0.5,1.6
ENSMUSG00000047428,DLK2,delta-like 2 homolog (Drosophila),membrane|integral component of membrane|extracellular vesicular exosome|,regulation of fat cell differentiation|negative regulation of Notch signaling pathway|,calcium ion binding|protein homodimerization activity|protein heterodimerization activity|,9,0.1,0.536,9,0.6,3.75,0.3,2.71,2.71,0.246,0,0,-1.2,1.5
ENSMUSG00000034175,RHBDD3,rhomboid domain containing 3,intracellular|membrane|integral component of membrane|,MAPK cascade|liver development|regulation of acute inflammatory response|response to xenobiotic stimulus|negative regulation of natural killer cell activation|positive regulation of protein catabolic process|regulation of protein secretion|,serine-type endopeptidase activity|protein binding|,10,0.3,1.57,10,0.3,1.33,0.3,2.71,2.71,0.246,0,0,-0.8,1.5
ENSMUSG00000049339,FAM134A,"family with sequence similarity 134, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,0.756,10,0.5,2.54,0.4,2.7,2.7,0.247,0,0,-0.9,1.6
ENSMUSG00000057193,SLC44A2,"solute carrier family 44, member 2",lysosomal membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|protein binding|,10,0.5,2.9,10,0.2,0.556,0.4,2.7,2.7,0.247,0,0,-0.4,1.6
ENSMUSG00000031007,ATP6AP2,"ATPase, H+ transporting, lysosomal accessory protein 2",external side of plasma membrane|membrane|integral component of membrane|neuron projection|cell body|extracellular vesicular exosome|,angiotensin maturation|proteolysis|rostrocaudal neural tube patterning|positive regulation of Wnt signaling pathway|positive regulation of Wnt signaling pathway|positive regulation of transforming growth factor beta1 production|regulation of MAPK cascade|eye pigmentation|head morphogenesis|,aspartic-type endopeptidase activity|receptor activity|enzyme binding|,10,0.2,0.527,10,0.5,2.58,0.4,2.69,2.69,0.248,0,0,-0.3,1.6
ENSMUSG00000036957,LRFN3,leucine rich repeat and fibronectin type III domain containing 3,plasma membrane|membrane|integral component of membrane|cell junction|cell projection|synapse|postsynaptic membrane|,cell adhesion|,None,10,0.3,3.49,10,-0.3,0.904,0.3,2.67,2.67,0.25,0,0,-1.4,1.1
ENSMUSG00000032392,PARP16,"poly (ADP-ribose) polymerase family, member 16",nucleus|nuclear envelope|endoplasmic reticulum|membrane|membrane|integral component of membrane|endoplasmic reticulum tubular network|,protein ADP-ribosylation|response to unfolded protein|activation of signaling protein activity involved in unfolded protein response|endoplasmic reticulum unfolded protein response|negative regulation of cell death|protein auto-ADP-ribosylation|positive regulation of protein serine/threonine kinase activity|,"NAD+ ADP-ribosyltransferase activity|NAD(P)+-protein-arginine ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|kinase binding|protein serine/threonine kinase activator activity|",10,0.1,0.747,10,0.5,3.19,0.3,2.67,2.67,0.25,0,0,-1.3,1.5
ENSMUSG00000043999,GPR75,G protein-coupled receptor 75,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.4,5.08,10,-0.3,0.839,0.4,2.65,2.65,0.251,0,0,-0.8,1.4
ENSMUSG00000062609,KCNJ15,"potassium inwardly-rectifying channel, subfamily J, member 15",plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|potassium channel activity|protein binding|,10,0.3,1.2,10,0.7,1.99,0.4,2.65,2.65,0.251,0,0,-0.5,1.7
ENSMUSG00000022514,IL1RAP,interleukin 1 receptor accessory protein,extracellular region|cytoplasm|plasma membrane|membrane|membrane|integral component of membrane|protein complex|,signal transduction|cytokine-mediated signaling pathway|interleukin-2 biosynthetic process|,signal transducer activity|interleukin-1 receptor activity|interleukin-1 receptor binding|protein binding|,10,-0.5,2.42,10,-0.4,0.429,-0.4,2.65,-2.65,0.251,0,0,-1.5,0.4
ENSMUSG00000035596,MBOAT7,membrane bound O-acyltransferase domain containing 7,membrane|membrane|integral component of membrane|,lipid metabolic process|phospholipid biosynthetic process|ventricular system development|layer formation in cerebral cortex|phosphatidylinositol metabolic process|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|lysophospholipid acyltransferase activity|",9,0.7,3.35,10,-0.5,1.77,0.7,2.65,2.65,0.251,0,0,-0.8,1.8
ENSMUSG00000038949,CNST,"consortin, connexin sorting protein",Golgi apparatus|trans-Golgi network|plasma membrane|membrane|membrane|integral component of membrane|transport vesicle|cytoplasmic vesicle|protein complex|,negative regulation of phosphatase activity|positive regulation of Golgi to plasma membrane protein transport|,protein binding|phosphatase binding|connexin binding|,10,0.4,2.8,10,1.3,2.09,0.5,2.64,2.64,0.252,0,0,-0.5,2
ENSMUSG00000040616,TMEM51,transmembrane protein 51,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,3.7,10,0.1,0.00361,0.4,2.64,2.64,0.252,0,0,-0.4,1.6
ENSMUSG00000027215,CD82,CD82 antigen,membrane|integral component of membrane|extracellular vesicular exosome|,None,None,10,-1.3,5.23,10,0.5,2.49,-1,2.63,-2.63,0.253,0,0,-2,0.7
ENSMUSG00000028246,FAXC,failed axon connections homolog (Drosophila),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,3.51,10,0,0,0.3,2.63,2.63,0.253,0,0,-0.5,1.5
ENSMUSG00000044071,FAM19A2,"family with sequence similarity 19, member A2",cellular_component|cytoplasm|,biological_process|,molecular_function|,10,-0.3,1.78,10,-0.4,1.08,-0.3,2.62,-2.62,0.254,0,0,-1.4,0.5
ENSMUSG00000026114,CNGA3,cyclic nucleotide gated channel alpha 3,photoreceptor outer segment|photoreceptor outer segment|cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|dendrite|photoreceptor outer segment membrane|neuronal cell body|perikaryon|transmembrane transporter complex|,"transport|ion transport|cation transport|cation transport|visual perception|phototransduction, visible light|response to magnesium ion|ion transmembrane transport|ion transmembrane transport|regulation of ion transmembrane transport|regulation of membrane potential|retinal cone cell development|response to stimulus|response to cAMP|transmembrane transport|potassium ion transmembrane transport|",nucleotide binding|ion channel activity|intracellular cyclic nucleotide activated cation channel activity|intracellular cAMP activated cation channel activity|intracellular cGMP activated cation channel activity|intracellular cGMP activated cation channel activity|voltage-gated potassium channel activity|protein binding|protein C-terminus binding|cGMP binding|cGMP binding|,10,0.3,2.53,10,0.2,0.326,0.3,2.61,2.61,0.255,0,0,-0.4,1.6
ENSMUSG00000053293,POM121,nuclear pore membrane protein 121,nucleus|nuclear pore|endoplasmic reticulum|membrane|integral component of membrane|,transport|nuclear pore organization|protein transport|mRNA transport|,structural constituent of nuclear pore|,10,-0.2,1.36,10,-1.5,5.26,-1.5,2.6,-2.6,0.256,0,0,-2.9,0
ENSMUSG00000023243,KCNK5,"potassium channel, subfamily K, member 5",membrane|integral component of membrane|,transport|ion transport|,None,10,0.4,1.81,10,0.3,1.09,0.4,2.59,2.59,0.257,0,0,-0.3,1.7
ENSMUSG00000054434,TMEM120B,transmembrane protein 120B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.36,10,-0.2,1.42,-0.2,2.57,-2.57,0.259,0,0,-1.4,0.4
ENSMUSG00000000085,SCMH1,sex comb on midleg homolog 1,nucleus|nucleus|chromocenter|,"chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|spermatogenesis|anterior/posterior pattern specification|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",protein binding|,10,0.5,3.05,10,1.7,2.73,0.5,2.57,2.57,0.259,0,0,-0.2,2.9
ENSMUSG00000030313,DENND5B,DENN/MADD domain containing 5B,membrane|integral component of membrane|,positive regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.6,2.94,10,-0.3,0.477,-0.4,2.57,-2.57,0.259,0,0,-1.6,0.6
ENSMUSG00000038179,SLAMF7,SLAM family member 7,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,regulation of natural killer cell activation|,receptor activity|protein binding|,10,0.4,3.73,10,0,0,0.3,2.57,2.57,0.259,0,0,-1.6,1.1
ENSMUSG00000020806,RHBDF2,rhomboid 5 homolog 2 (Drosophila),endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|membrane|integral component of membrane|,proteolysis|transport|protein transport|negative regulation of protein secretion|,None,10,0.3,2.17,10,0.3,0.581,0.3,2.57,2.57,0.259,0,0,-0.6,1.5
ENSMUSG00000074342,I830077J02RIK,RIKEN cDNA I830077J02 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1,5.27,10,0,0,0.9,2.55,2.55,0.261,0,0,-0.2,2
ENSMUSG00000025521,TMEM192,transmembrane protein 192,lysosome|lysosomal membrane|endosome|late endosome|membrane|integral component of membrane|perinuclear region of cytoplasm|extracellular vesicular exosome|,biological_process|,protein homodimerization activity|,10,-0.1,0.108,10,0.7,4.38,0.5,2.54,2.54,0.262,0,0,-0.5,1.8
ENSMUSG00000039704,LMBRD2,LMBR1 domain containing 2,membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.7,4.91,0.4,2.52,2.52,0.264,0,0,-0.1,1.8
ENSMUSG00000038604,FAM65A,"family with sequence similarity 65, member A",cytoplasm|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,1.1,3.99,0.8,2.47,2.47,0.269,0,0,0,2
ENSMUSG00000060470,GPR97,G protein-coupled receptor 97,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0.5,2.58,10,0.2,0.898,0.4,2.47,2.47,0.269,0,0,-0.4,1.6
ENSMUSG00000031364,GRPR,gastrin releasing peptide receptor,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|learning or memory|bombesin receptor signaling pathway|social behavior|regulation of cell proliferation|,signal transducer activity|G-protein coupled receptor activity|bombesin receptor activity|protein binding|neuropeptide binding|,10,-0.3,2.52,10,0.7,0.669,-0.2,2.46,-2.46,0.27,0,0,-1.3,1.5
ENSMUSG00000031021,TMEM9B,"TMEM9 domain family, member B",cellular_component|membrane|integral component of membrane|,signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|,10,0.2,0.902,10,0.5,2.75,0.2,2.46,2.46,0.27,0,0,-0.7,1.5
ENSMUSG00000047037,NIPA1,non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human),endosome|early endosome|plasma membrane|membrane|integral component of membrane|,transport|ion transport|magnesium ion transport|,magnesium ion transmembrane transporter activity|,10,-0.1,0.345,10,0.5,3.92,0.5,2.44,2.44,0.272,0,0,-0.9,1.7
ENSMUSG00000039878,SLC39A5,"solute carrier family 39 (metal ion transporter), member 5",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|extracellular vesicular exosome|,transport|ion transport|zinc ion transport|cellular zinc ion homeostasis|metal ion transport|cellular response to zinc ion starvation|transmembrane transport|,metal ion transmembrane transporter activity|,10,0.5,2.05,10,0.3,0.745,0.4,2.43,2.43,0.273,0,0,-0.6,1.6
ENSMUSG00000048807,SLC35E4,"solute carrier family 35, member E4",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.8,1.56,10,-0.3,3.16,-0.3,2.41,-2.41,0.275,0,0,-1.3,1.6
ENSMUSG00000001627,IFRD1,interferon-related developmental regulator 1,nucleus|,multicellular organismal development|adult somatic muscle development|cell differentiation|muscle cell differentiation|,None,10,0.2,1.1,10,0.4,1.8,0.3,2.41,2.41,0.275,0,0,-0.6,1.7
ENSMUSG00000029924,SLC37A3,"solute carrier family 37 (glycerol-3-phosphate transporter), member 3",cellular_component|membrane|integral component of membrane|,transport|biological_process|carbohydrate transport|transmembrane transport|,molecular_function|transporter activity|,10,0.6,5.01,10,-0.5,2.5,0.5,2.4,2.4,0.276,0,0,-1.4,1.5
ENSMUSG00000073139,BC023829,cDNA sequence BC023829,membrane|integral component of membrane|dendrite|cell projection|,biological_process|,molecular_function|,10,-0.5,3.78,10,0.2,0.647,-0.4,2.4,-2.4,0.276,0,0,-1.7,0.6
ENSMUSG00000030029,LRIG1,leucine-rich repeats and immunoglobulin-like domains 1,membrane|integral component of membrane|,sensory perception of sound|otolith morphogenesis|innervation|,None,10,-0.6,2.27,10,-1.1,0.987,-0.6,2.38,-2.38,0.278,0,0,-1.9,0.6
ENSMUSG00000022131,GPR180,G protein-coupled receptor 180,membrane|integral component of membrane|extracellular vesicular exosome|,G-protein coupled receptor signaling pathway|biological_process|response to pheromone|,molecular_function|,10,-0.6,1.47,10,-0.3,1.58,-0.3,2.38,-2.38,0.278,0,0,-1.6,0.9
ENSMUSG00000078681,TM2D3,TM2 domain containing 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.71,10,0.4,1.17,0.4,2.38,2.38,0.278,0,0,-0.9,1.5
ENSMUSG00000032131,ABCG4,"ATP-binding cassette, sub-family G (WHITE), member 4",None,None,nucleotide binding|ATP binding|protein homodimerization activity|protein heterodimerization activity|,10,-0.1,0.0418,10,-0.7,4.15,-0.6,2.36,-2.36,0.281,0,0,-1.9,0.6
ENSMUSG00000036009,METTL25,methyltransferase like 25,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.5,2.94,10,0.2,0.249,-0.4,2.35,-2.35,0.282,0,0,-1.1,1.9
ENSMUSG00000004798,ULK2,unc-51 like kinase 2,cytosol|membrane|cytoplasmic vesicle|pre-autophagosomal structure membrane|pre-autophagosomal structure membrane|Atg1p signaling complex|,autophagic vacuole assembly|protein phosphorylation|autophagy|signal transduction|nervous system development|axonogenesis|regulation of autophagy|regulation of autophagy|phosphorylation|response to starvation|protein autophosphorylation|protein autophosphorylation|negative regulation of collateral sprouting|axon extension|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.8,3.57,10,0.1,0.189,0.2,2.33,2.33,0.284,0,0,-0.2,1.9
ENSMUSG00000047731,WBP1L,WW domain binding protein 1 like,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.3,4.19,10,0.3,0.203,0.4,2.3,2.3,0.287,0,0,-0.3,2
ENSMUSG00000006221,HSPB7,"heat shock protein family, member 7 (cardiovascular)",nucleus|cytoplasm|mitochondrion|actin cytoskeleton|,response to stress|response to heat|,filamin binding|,10,-0.7,3.16,10,0.6,3.96,0.4,2.28,2.28,0.289,0,0,-1.5,1.5
ENSMUSG00000030789,ITGAX,integrin alpha X,integrin complex|external side of plasma membrane|cell surface|membrane|membrane|integral component of membrane|,cell adhesion|integrin-mediated signaling pathway|defense response to virus|,metal ion binding|,10,0,0,10,0.4,3.85,0.4,2.24,2.24,0.294,0,0,-0.3,1.6
ENSMUSG00000037997,PARP11,"poly (ADP-ribose) polymerase family, member 11",cellular_component|,biological_process|,"molecular_function|NAD+ ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.9,3.19,10,-0.3,0.529,-0.3,2.23,-2.23,0.295,0,0,-1.5,1.7
ENSMUSG00000040828,CATSPERD,catsper channel auxiliary subunit delta,plasma membrane|cilium|membrane|integral component of membrane|CatSper complex|cell projection|sperm principal piece|,multicellular organismal development|spermatogenesis|cell differentiation|sperm motility|sperm capacitation|,molecular_function|,10,0.6,4.23,10,-0.1,0.334,0.5,2.22,2.22,0.296,0,0,-0.7,1.7
ENSMUSG00000045282,TMEM86B,transmembrane protein 86B,cytoplasm|membrane|integral component of membrane|,ether lipid metabolic process|,hydrolase activity|alkenylglycerophosphocholine hydrolase activity|alkenylglycerophosphoethanolamine hydrolase activity|,10,-0.4,2.03,10,1.2,0.985,-0.3,2.21,-2.21,0.297,0,0,-1.2,1.9
ENSMUSG00000087370,TMEM170B,transmembrane protein 170B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.248,10,-1.6,5.53,-1.6,2.21,-2.21,0.297,0,0,-3,0.2
ENSMUSG00000035245,EOGT,EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase,cellular_component|endoplasmic reticulum|,protein O-linked glycosylation|metabolic process|,"protein N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.2,0.662,10,-0.3,1.83,-0.3,2.21,-2.21,0.297,0,0,-1.5,0.6
ENSMUSG00000063019,MANBAL,"mannosidase, beta A, lysosomal-like",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.95,10,-1,0.811,-0.5,2.19,-2.19,0.299,0,0,-1.7,1.1
ENSMUSG00000063873,SLC24A3,"solute carrier family 24 (sodium/potassium/calcium exchanger), member 3",plasma membrane|plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|potassium ion transport|sodium ion transport|calcium ion transport|cellular calcium ion homeostasis|sodium ion transmembrane transport|sodium ion transmembrane transport|transmembrane transport|calcium ion transmembrane transport|calcium ion transmembrane transport|potassium ion transmembrane transport|,"calcium, potassium:sodium antiporter activity|calcium, potassium:sodium antiporter activity|calcium, potassium:sodium antiporter activity|symporter activity|antiporter activity|",10,0.3,2.49,10,0.1,0.0923,0.3,2.19,2.19,0.299,0,0,-0.8,1.5
ENSMUSG00000034845,PLVAP,plasmalemma vesicle associated protein,intracellular|cytoplasm|plasma membrane|caveola|caveola|cell surface|membrane|integral component of membrane|,MAPK cascade|positive regulation of cellular extravasation|positive regulation of cellular extravasation|tumor necrosis factor-mediated signaling pathway|,protein homodimerization activity|,10,0.5,2.95,10,0.1,0.0592,0.3,2.19,2.19,0.299,0,0,-0.5,1.6
ENSMUSG00000028618,TMEM59,transmembrane protein 59,Golgi cis cisterna|Golgi trans cisterna|lysosome|endosome|late endosome|Golgi apparatus|Golgi medial cisterna|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,proteolysis|autophagy|positive regulation of autophagy|negative regulation of protein processing|negative regulation of establishment of protein localization to plasma membrane|negative regulation of protein glycosylation in Golgi|,endopeptidase activity|,10,-0.7,4.59,10,0.5,0.766,-0.4,2.18,-2.18,0.3,0,0,-1.8,1.2
ENSMUSG00000073434,WDR90,WD repeat domain 90,cellular_component|,biological_process|,molecular_function|,10,0.3,1.39,10,0.2,0.906,0.2,2.13,2.13,0.306,0,0,-0.9,1.4
ENSMUSG00000022560,SLC52A2,"solute carrier protein 52, member 2",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|riboflavin transport|,riboflavin transporter activity|,10,-0.5,1.85,10,-0.3,0.791,-0.3,2.13,-2.13,0.306,0,0,-1.7,0.4
ENSMUSG00000044393,DSG2,desmoglein 2,plasma membrane|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|cell junction|desmosome|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|ventricular cardiac muscle cell action potential|bundle of His cell to Purkinje myocyte communication|regulation of heart rate by cardiac conduction|,calcium ion binding|metal ion binding|,10,0.3,1.73,10,0.3,0.549,0.3,2.12,2.12,0.308,0,0,-0.5,1.6
ENSMUSG00000034652,CD300A,CD300A antigen,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,"immune system process|serotonin secretion by mast cell|receptor-mediated endocytosis|signal transduction|negative regulation of serotonin secretion|negative regulation of B cell proliferation|positive regulation of phosphoprotein phosphatase activity|negative regulation of mast cell activation involved in immune response|negative regulation of mast cell degranulation|negative regulation of mast cell degranulation|negative regulation of MAP kinase activity|negative regulation of fibroblast proliferation|regulation of T cell receptor signaling pathway|negative regulation of B cell receptor signaling pathway|negative regulation of NK T cell activation|negative regulation of phagocytosis, engulfment|negative regulation of neutrophil activation|negative regulation of eosinophil activation|negative regulation of activation of JAK2 kinase activity|negative regulation of eosinophil migration|",phosphatidylserine binding|protein binding|phosphatidylethanolamine binding|phosphatase binding|signaling receptor activity|,10,-0.4,1.09,10,-0.4,1.19,-0.4,2.12,-2.12,0.308,0,0,-1.6,0.7
ENSMUSG00000053730,TMEM39B,transmembrane protein 39b,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.82,10,-0.5,0.736,-0.3,2.12,-2.12,0.308,0,0,-1.5,1.1
ENSMUSG00000034265,ZDHHC14,"zinc finger, DHHC domain containing 14",endoplasmic reticulum|membrane|integral component of membrane|,protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.3,1.4,10,0.4,0.88,0.3,2.09,2.09,0.311,0,0,-0.6,1.7
ENSMUSG00000023349,CLEC4N,"C-type lectin domain family 4, member n",membrane|integral component of membrane|,immune system process|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|positive regulation of cytokine secretion|defense response to fungus|,protein binding|carbohydrate binding|,10,0.2,1.59,10,0.3,0.632,0.3,2.03,2.03,0.319,0,0,-1,1.4
ENSMUSG00000023909,PAQR4,progestin and adipoQ receptor family member IV,cellular_component|membrane|integral component of membrane|,biological_process|,receptor activity|,10,0,0,10,0.4,3.46,0.3,2.02,2.02,0.32,0,0,-0.5,1.6
ENSMUSG00000041734,KIRREL,kin of IRRE like (Drosophila),plasma membrane|plasma membrane|cell-cell junction|cell-cell junction|membrane|integral component of membrane|cell projection membrane|dendritic shaft|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,negative regulation of protein phosphorylation|excretion|single organismal cell-cell adhesion|single organismal cell-cell adhesion|positive regulation of actin filament polymerization|,protein binding|myosin binding|,10,-0.2,0.363,10,-0.2,1.78,-0.2,2,-2,0.322,0,0,-1.4,1.5
ENSMUSG00000002897,IL17RA,interleukin 17 receptor A,plasma membrane|membrane|integral component of membrane|,positive regulation of interleukin-23 production|cellular response to cytokine stimulus|fibroblast activation|positive regulation of cytokine production involved in inflammatory response|,None,10,-0.5,3.82,10,0,0,-0.4,1.99,-1.99,0.324,0,0,-1.8,0.4
ENSMUSG00000002980,BCAM,basal cell adhesion molecule,plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|cell-matrix adhesion|,laminin receptor activity|laminin receptor activity|laminin binding|,10,-0.2,0.282,10,-0.7,2.76,-0.6,1.99,-1.99,0.324,0,0,-1.8,1
ENSMUSG00000006469,SLC34A3,"solute carrier family 34 (sodium phosphate), member 3",brush border|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|cytoplasmic vesicle|brush border membrane|,transport|ion transport|sodium ion transport|phosphate ion transport|phosphate ion transport|cellular phosphate ion homeostasis|phosphate ion transmembrane transport|phosphate ion transmembrane transport|sodium ion transmembrane transport|sodium-dependent phosphate transport|,sodium:phosphate symporter activity|symporter activity|sodium-dependent phosphate transmembrane transporter activity|sodium-dependent phosphate transmembrane transporter activity|,10,-0.3,0.512,10,-1.4,3.77,-0.4,1.97,-1.97,0.326,0,0,-2,0.2
ENSMUSG00000000552,ZFP385A,zinc finger protein 385A,nuclear chromatin|nucleus|cytoplasm|dendrite|cell projection|neuronal cell body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|apoptotic process|cellular response to DNA damage stimulus|cell cycle|hemostasis|learning or memory|locomotory behavior|intracellular mRNA localization|mRNA localization resulting in posttranscriptional regulation of gene expression|platelet formation|megakaryocyte development|megakaryocyte development|positive regulation of fat cell differentiation|platelet alpha granule organization|positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|regulation of cytoplasmic translation|",p53 binding|nucleic acid binding|RNA binding|mRNA 3'-UTR binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,-0.5,3.08,10,0,0,-0.5,1.97,-1.97,0.326,0,0,-1.7,0.9
ENSMUSG00000022474,PMM1,phosphomannomutase 1,cytoplasm|neuronal cell body|,mannose metabolic process|metabolic process|mannose biosynthetic process|,catalytic activity|phosphomannomutase activity|isomerase activity|metal ion binding|,10,0.2,1.41,10,-0.7,2.45,-0.4,1.96,-1.96,0.328,0,0,-1.7,0.8
ENSMUSG00000096188,CMTM4,CKLF-like MARVEL transmembrane domain containing 4,cellular_component|extracellular space|membrane|integral component of membrane|,chemotaxis|biological_process|,molecular_function|cytokine activity|,10,-0.2,1.56,10,-1,1.01,-0.2,1.9,-1.9,0.336,0,0,-1.9,0.7
ENSMUSG00000031129,SLC9A9,"solute carrier family 9 (sodium/hydrogen exchanger), member 9",endosome|membrane|integral component of membrane|recycling endosome|,transport|ion transport|cation transport|sodium ion transport|regulation of pH|transmembrane transport|,antiporter activity|solute:proton antiporter activity|sodium:proton antiporter activity|,10,0.1,0.00394,10,0.4,2.24,0.4,1.89,1.89,0.337,0,0,-0.4,1.7
ENSMUSG00000026123,PLEKHB2,"pleckstrin homology domain containing, family B (evectins) member 2",cellular_component|endosome|membrane|,biological_process|,molecular_function|,10,0.2,0.258,10,0.7,2.85,0.3,1.87,1.87,0.34,0,0,-0.5,1.8
ENSMUSG00000026000,LANCL1,LanC (bacterial lantibiotic synthetase component C)-like 1,nucleus|cytoplasm|membrane|extracellular vesicular exosome|,None,catalytic activity|zinc ion binding|SH3 domain binding|glutathione binding|metal ion binding|low-density lipoprotein particle receptor binding|,10,-0.8,3.98,10,0,0,-0.7,1.86,-1.86,0.342,0,0,-2,0.5
ENSMUSG00000024857,CABP2,calcium binding protein 2,cytoplasm|Golgi apparatus|plasma membrane|membrane|,None,calcium ion binding|metal ion binding|,10,0.3,2.62,10,0,0,0.2,1.85,1.85,0.343,0,0,-1,1.4
ENSMUSG00000054400,CKLF,chemokine-like factor,extracellular region|extracellular space|cell|membrane|membrane|integral component of membrane|,chemotaxis|cell proliferation|neutrophil chemotaxis|leukocyte chemotaxis|secretion by cell|macrophage chemotaxis|lymphocyte chemotaxis|,cytokine activity|chemokine activity|,10,0.5,3.72,10,0,0,0.4,1.85,1.85,0.343,0,0,-0.4,1.8
ENSMUSG00000033192,LPCAT2,lysophosphatidylcholine acyltransferase 2,endoplasmic reticulum|endoplasmic reticulum|Golgi apparatus|Golgi stack|lipid particle|membrane|integral component of membrane|,lipid metabolic process|platelet activating factor biosynthetic process|metabolic process|phospholipid biosynthetic process|phosphatidylcholine acyl-chain remodeling|membrane organization|,"1-acylglycerol-3-phosphate O-acyltransferase activity|calcium ion binding|transferase activity|transferase activity, transferring acyl groups|metal ion binding|1-acylglycerophosphocholine O-acyltransferase activity|1-acylglycerophosphocholine O-acyltransferase activity|1-alkylglycerophosphocholine O-acetyltransferase activity|",9,0.3,0.337,9,0.4,1.7,0.4,1.84,1.84,0.344,0,0,-0.8,1.7
ENSMUSG00000019734,TMC4,transmembrane channel-like gene family 4,cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.2,0.631,10,0.3,1.56,0.2,1.84,1.84,0.344,0,0,-1,1.4
ENSMUSG00000033159,CNPPD1,cyclin Pas1/PHO80 domain containing 1,cellular_component|membrane|integral component of membrane|,regulation of cyclin-dependent protein serine/threonine kinase activity|biological_process|,molecular_function|protein kinase binding|,10,0.5,3.21,10,0,0,0.4,1.84,1.84,0.344,0,0,-0.7,1.6
ENSMUSG00000047045,TMEM164,transmembrane protein 164,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,3.43,10,0,0,0.6,1.83,1.83,0.346,0,0,-0.2,1.9
ENSMUSG00000052581,LRRTM4,leucine rich repeat transmembrane neuronal 4,plasma membrane|membrane|integral component of membrane|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|postsynaptic membrane|,synapse organization|neurotransmitter-gated ion channel clustering|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|regulation of presynaptic membrane organization|,heparan sulfate proteoglycan binding|,10,-0.2,1.37,10,0.5,2.63,0.8,1.82,1.82,0.347,0,0,-1,1.9
ENSMUSG00000039646,VASN,vasorin,extracellular space|mitochondrion|lysosomal membrane|plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,negative regulation of epithelial to mesenchymal transition|negative regulation of transforming growth factor beta receptor signaling pathway|cellular response to hypoxia|cellular response to redox state|,protein binding|transforming growth factor beta binding|,10,-0.1,0.385,10,-0.3,2.16,-0.3,1.81,-1.81,0.349,0,0,-1.7,0.6
ENSMUSG00000045009,PRRT3,proline-rich transmembrane protein 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.206,10,-0.5,2.97,-0.2,1.8,-1.8,0.35,0,0,-1.8,0.3
ENSMUSG00000062524,NCR1,natural cytotoxicity triggering receptor 1,plasma membrane|membrane|integral component of membrane|,None,None,10,0.2,0.95,10,0.5,1.28,0.4,1.79,1.79,0.352,0,0,-1.4,1.6
ENSMUSG00000037110,RALGAPA2,"Ral GTPase activating protein, alpha subunit 2 (catalytic)",extracellular space|intracellular|cytoplasm|cytoplasm|plasma membrane|,Ral protein signal transduction|activation of Ral GTPase activity|activation of Ral GTPase activity|regulation of protein localization|regulation of small GTPase mediated signal transduction|regulation of exocyst localization|,GTPase activator activity|Ral GTPase activator activity|Ral GTPase activator activity|protein heterodimerization activity|,10,0.3,1.07,10,0.3,0.868,0.3,1.79,1.79,0.352,0,0,-0.6,1.7
ENSMUSG00000028270,GBP2,guanylate binding protein 2,nucleus|cytoplasm|Golgi apparatus|membrane|symbiont-containing vacuole membrane|cytoplasmic vesicle|,GTP catabolic process|cellular response to interferon-beta|defense response to protozoan|adhesion of symbiont to host|defense response to Gram-positive bacterium|cellular response to lipopolysaccharide|cellular response to interferon-gamma|,nucleotide binding|GTPase activity|GTP binding|,10,0.1,0.0233,10,-1.3,5.08,-1.3,1.79,-1.79,0.352,0,0,-2,0.5
ENSMUSG00000037419,ENDOD1,endonuclease domain containing 1,extracellular region|membrane|extracellular vesicular exosome|,biological_process|,nucleic acid binding|nuclease activity|endonuclease activity|hydrolase activity|metal ion binding|,10,0,0,10,0.8,4.67,0.6,1.78,1.78,0.353,0,0,-0.1,2
ENSMUSG00000036658,OLFR11,olfactory receptor 11,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.7,2.36,10,-0.2,0.655,-0.4,1.77,-1.77,0.355,0,0,-1.9,1
ENSMUSG00000067377,TSPAN6,tetraspanin 6,membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of NIK/NF-kappaB signaling|,signal transducer activity|,10,-0.4,2.54,10,0,0,-0.3,1.76,-1.76,0.356,0,0,-1.7,0.6
ENSMUSG00000055963,TRIQK,triple QxxK/R motif containing,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,None,None,10,0.2,1.3,10,1.7,4.23,0.5,1.74,1.74,0.359,0,0,-0.1,2.9
ENSMUSG00000051663,PCDHB1,protocadherin beta 1,plasma membrane|membrane|integral component of membrane|,cell adhesion|,None,10,0.1,0.0795,10,0.4,2.45,0.3,1.7,1.7,0.366,0,0,-0.8,1.6
ENSMUSG00000060621,NKPD1,"NTPase, KAP family P-loop domain containing 1",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,2.07,10,0.1,0.125,-0.4,1.67,-1.67,0.37,0,0,-1.7,0.8
ENSMUSG00000071000,OLFR155,olfactory receptor 155,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|sensory perception of smell|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|olfactory receptor activity|,10,0.3,1.93,10,0.1,0.075,0.2,1.67,1.67,0.37,0,0,-0.7,1.6
ENSMUSG00000034320,SLC26A2,"solute carrier family 26 (sulfate transporter), member 2",membrane|integral component of membrane|,ossification|transport|sulfate transport|transmembrane transport|sulfate transmembrane transport|,secondary active sulfate transmembrane transporter activity|sulfate transmembrane transporter activity|,10,-0.3,0.259,10,-0.3,1.53,-0.3,1.67,-1.67,0.37,0,0,-1.7,0.7
ENSMUSG00000073725,LMBRD1,LMBR1 domain containing 1,lysosome|plasma membrane|membrane|membrane|integral component of membrane|clathrin-coated endocytic vesicle|,transport|insulin receptor internalization|negative regulation of glucose import|negative regulation of insulin receptor signaling pathway|negative regulation of protein kinase B signaling|,insulin receptor binding|cobalamin binding|,10,0.2,0.395,10,0.3,1.62,0.2,1.67,1.67,0.37,0,0,-1.4,1.5
ENSMUSG00000030650,TMC5,transmembrane channel-like gene family 5,cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.7,3.53,10,-1.3,3.52,0.4,1.67,1.67,0.37,0,0,-2,1.4
ENSMUSG00000021556,GOLM1,golgi membrane protein 1,extracellular space|Golgi apparatus|Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,nucleus organization|regulation of lipid metabolic process|,molecular_function|,10,1.1,4.55,10,-0.5,0.913,1,1.65,1.65,0.373,0,0,-0.7,2
ENSMUSG00000022610,MAPK12,mitogen-activated protein kinase 12,nucleus|cytoplasm|mitochondrion|,"MAPK cascade|transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|response to stress|cell cycle|phosphorylation|peptidyl-serine phosphorylation|myoblast differentiation|negative regulation of cell cycle|","nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.2,0.74,10,-0.8,2.24,-0.4,1.64,-1.64,0.375,0,0,-1.9,0.5
ENSMUSG00000033396,SPG11,spastic paraplegia 11,nucleus|nucleolus|cytoplasm|lysosomal membrane|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.4,1.84,10,0.4,1.91,0.3,1.63,1.63,0.377,0,0,-1.3,1.5
ENSMUSG00000050818,OLFR330,olfactory receptor 330,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.38,10,0.8,3.08,0.4,1.62,1.62,0.379,0,0,-0.6,1.9
ENSMUSG00000033114,SLC35D2,"solute carrier family 35, member D2",cellular_component|Golgi apparatus|membrane|integral component of membrane|,transport|biological_process|carbohydrate transport|,molecular_function|,10,0.3,1.23,10,0.3,0.506,0.3,1.61,1.61,0.38,0,0,-0.6,1.7
ENSMUSG00000070305,MPZL3,myelin protein zero-like 3,membrane|integral component of membrane|,cell adhesion|extracellular matrix organization|hair cycle|,None,10,0.4,1.65,10,0.1,0.149,0.3,1.6,1.6,0.382,0,0,-0.9,1.6
ENSMUSG00000049676,CATSPERG1,catsper channel auxiliary subunit gamma 1,cellular_component|membrane|integral component of membrane|CatSper complex|sperm principal piece|,biological_process|,molecular_function|,10,1,1.84,10,0.2,0.225,0.2,1.6,1.6,0.382,0,0,-0.3,2
ENSMUSG00000042650,ALKBH5,"alkB, alkylation repair homolog 5 (E. coli)",nucleus|nuclear speck|,response to hypoxia|mRNA processing|mRNA export from nucleus|spermatogenesis|cell differentiation|oxidative single-stranded RNA demethylation|oxidation-reduction process|,"sulfonate dioxygenase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|oxidative RNA demethylase activity|DNA-N1-methyladenine dioxygenase activity|poly(A) RNA binding|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.2,1.22,10,0.2,0.509,0.2,1.6,1.6,0.382,0,0,-1.1,1.4
ENSMUSG00000023169,SLC38A1,"solute carrier family 38, member 1",plasma membrane|membrane|integral component of membrane|axon|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|amino acid transport|glutamine transport|L-alpha-amino acid transmembrane transport|,L-glutamine transmembrane transporter activity|symporter activity|,10,-0.6,3.41,10,0.3,1.67,-0.5,1.6,-1.6,0.382,0,0,-1.7,0.9
ENSMUSG00000036578,FXYD7,FXYD domain-containing ion transport regulator 7,membrane|integral component of membrane|,transport|ion transport|regulation of ion transport|,ion channel activity|ATPase binding|,10,-0.4,0.708,10,-0.2,1.06,-0.2,1.59,-1.59,0.384,0,0,-1.7,1
ENSMUSG00000025777,GDAP1,ganglioside-induced differentiation-associated-protein 1,nucleus|cytoplasm|mitochondrion|mitochondrial outer membrane|membrane|membrane|integral component of membrane|integral component of mitochondrial outer membrane|,mitochondrial fission|protein targeting to mitochondrion|response to retinoic acid|,molecular_function|,10,0.3,1.97,10,0.1,0.325,0.3,1.58,1.58,0.385,0,0,-0.6,1.7
ENSMUSG00000021140,PCNX,pecanex homolog (Drosophila),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,0.443,10,-0.3,1.25,-0.3,1.57,-1.57,0.387,0,0,-1.7,0.6
ENSMUSG00000028033,KCNQ5,"potassium voltage-gated channel, subfamily Q, member 5",voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|potassium ion transport|regulation of ion transmembrane transport|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.9,0.757,10,0.3,1.34,0.2,1.55,1.55,0.39,0,0,-0.3,1.9
ENSMUSG00000037031,TSPAN15,tetraspanin 15,plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|tetraspanin-enriched microdomain|,protein maturation|protein maturation|establishment of protein localization to plasma membrane|,enzyme binding|enzyme binding|,10,0.3,1.4,10,0.2,0.281,0.2,1.55,1.55,0.39,0,0,-1,1.5
ENSMUSG00000039294,BC017643,cDNA sequence BC017643,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.9,3,10,-0.1,0.0222,0.2,1.55,1.55,0.39,0,0,-0.6,2
ENSMUSG00000039461,TCTA,T cell leukemia translocation altered gene,membrane|integral component of membrane|,None,None,10,-0.1,0.037,10,-1.6,4.82,-1.6,1.54,-1.54,0.392,0,0,-3,0.2
ENSMUSG00000006241,CCDC159,coiled-coil domain containing 159,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.727,10,-1.1,1.18,-0.2,1.53,-1.53,0.394,0,0,-2,0.4
ENSMUSG00000056938,ACBD4,acyl-Coenzyme A binding domain containing 4,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.913,10,0.5,2.27,0.3,1.53,1.53,0.394,0,0,-0.9,1.6
ENSMUSG00000022664,SLC35A5,"solute carrier family 35, member A5",Golgi membrane|membrane|integral component of membrane|,transport|biological_process|carbohydrate transport|nucleotide-sugar transport|,molecular_function|nucleotide-sugar transmembrane transporter activity|sugar:proton symporter activity|,10,-0.3,1.89,10,-0.1,0.0827,-0.2,1.53,-1.53,0.394,0,0,-1.5,1.1
ENSMUSG00000078201,TMEM203,transmembrane protein 203,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,1.94,10,-0.9,4.17,-0.5,1.53,-1.53,0.394,0,0,-1.9,0.8
ENSMUSG00000047843,BRI3,brain protein I3,membrane|integral component of membrane|,None,identical protein binding|,10,0.4,2.98,10,-1.6,4.55,0.3,1.52,1.52,0.395,0,0,-2.9,0.9
ENSMUSG00000021504,B4GALT7,"xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)",Golgi apparatus|membrane|integral component of membrane|extracellular matrix|,carbohydrate metabolic process|glycosaminoglycan biosynthetic process|proteoglycan metabolic process|protein N-linked glycosylation|extracellular fibril organization|negative regulation of fibroblast proliferation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|manganese ion binding|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|xylosylprotein 4-beta-galactosyltransferase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.4,1.61,10,0.2,0.331,0.3,1.52,1.52,0.395,0,0,-0.7,1.6
ENSMUSG00000028073,PEAR1,platelet endothelial aggregation receptor 1,phagocytic cup|plasma membrane|membrane|integral component of membrane|,recognition of apoptotic cell|recognition of apoptotic cell|,molecular_function|,10,-0.1,0.436,10,-0.3,1.61,-0.2,1.5,-1.5,0.399,0,0,-1.7,0.6
ENSMUSG00000054484,TMEM62,transmembrane protein 62,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.9,2,10,0.4,0.223,0.8,1.5,1.5,0.399,0,0,-0.7,2
ENSMUSG00000005950,P2RX5,"purinergic receptor P2X, ligand-gated ion channel, 5",integral component of nuclear inner membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|cation transport|cell surface receptor signaling pathway|neuronal action potential|ion transmembrane transport|purinergic nucleotide receptor signaling pathway|regulation of skeletal muscle tissue regeneration|protein homooligomerization|,purinergic nucleotide receptor activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|ATP binding|GTP binding|drug binding|zinc ion binding|,10,1.1,0.323,10,0.4,2.52,0.3,1.48,1.48,0.402,0,0,-0.4,1.9
ENSMUSG00000056004,9330182L06RIK,RIKEN cDNA 9330182L06 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.955,10,0.3,0.711,0.3,1.48,1.48,0.402,0,0,-0.4,1.9
ENSMUSG00000036304,ZDHHC23,"zinc finger, DHHC domain containing 23",cellular_component|membrane|integral component of membrane|,protein palmitoylation|protein localization to plasma membrane|,"molecular_function|zinc ion binding|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,-0.6,2.44,10,-0.3,0.274,-0.3,1.48,-1.48,0.402,0,0,-1.8,0.9
ENSMUSG00000026519,TMEM63A,transmembrane protein 63a,lysosome|lysosomal membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|biological_process|,nucleotide binding|molecular_function|,10,0.2,1.43,10,-0.4,2.38,0.2,1.47,1.47,0.404,0,0,-1.5,1.1
ENSMUSG00000043398,GPR135,G protein-coupled receptor 135,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.7,2.14,10,-0.3,0.101,-0.4,1.47,-1.47,0.404,0,0,-2,0.5
ENSMUSG00000034445,CYB561A3,"cytochrome b561 family, member A3",lysosome|lysosomal membrane|lysosomal membrane|endosome|membrane|integral component of membrane|late endosome membrane|,transport|biological_process|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|epoxyqueuosine reductase activity|,10,0,0,10,-0.5,2.41,-0.4,1.47,-1.47,0.404,0,0,-1.9,0.5
ENSMUSG00000039568,UBALD1,UBA-like domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.02,10,-0.4,2,-0.3,1.47,-1.47,0.404,0,0,-1.5,1
ENSMUSG00000056529,PTAFR,platelet-activating factor receptor,intracellular|plasma membrane|membrane|integral component of membrane|,cytokine production|pattern recognition receptor signaling pathway|chemotaxis|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|lipopolysaccharide-mediated signaling pathway|response to lipopolysaccharide|inositol trisphosphate biosynthetic process|phosphatidylinositol-mediated signaling|,lipopolysaccharide binding|lipopolysaccharide receptor activity|signal transducer activity|G-protein coupled receptor activity|platelet activating factor receptor activity|phospholipid binding|,10,0.2,1.25,10,0.2,0.325,0.2,1.46,1.46,0.406,0,0,-0.8,1.6
ENSMUSG00000037944,CCR7,chemokine (C-C motif) receptor 7,intracellular|intracellular|cell|plasma membrane|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,establishment of T cell polarity|myeloid dendritic cell chemotaxis|lymphocyte chemotaxis across high endothelial venule|positive regulation of dendritic cell antigen processing and presentation|regulation of tolerance induction to self antigen|positive regulation of hypersensitivity|positive regulation of humoral immune response|chemotaxis|inflammatory response|inflammatory response|immune response|signal transduction|G-protein coupled receptor signaling pathway|activation of JUN kinase activity|positive regulation of macrophage chemotaxis|positive regulation of T cell chemotaxis|actin cytoskeleton organization|positive regulation of Ras GTPase activity|response to lipopolysaccharide|regulation of interferon-gamma production|positive regulation of interleukin-12 production|positive regulation of tumor necrosis factor production|response to prostaglandin E|chemokine (C-C motif) ligand 19 signaling pathway|chemokine (C-C motif) ligand 21 signaling pathway|positive regulation of T cell proliferation|positive regulation of Cdc42 GTPase activity|negative thymic T cell selection|positive regulation of T-helper 1 cell differentiation|positive regulation of receptor-mediated endocytosis|lymph node development|regulation of interleukin-1 beta secretion|positive regulation of interleukin-1 beta secretion|positive regulation of phagocytosis|positive regulation of T cell receptor signaling pathway|positive regulation of filopodium assembly|chemokine-mediated signaling pathway|cellular response to cytokine stimulus|response to nitric oxide|interleukin-12 secretion|positive regulation of neutrophil chemotaxis|positive regulation of neutrophil chemotaxis|lymphocyte migration into lymph node|mature dendritic cell differentiation|negative regulation of leukocyte apoptotic process|positive regulation of cell motility|positive regulation of thymocyte migration|positive regulation of dendritic cell chemotaxis|positive regulation of immunological synapse formation|positive regulation of T cell costimulation|positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation|regulation of dendritic cell dendrite assembly|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|chemokine (C-C motif) ligand 19 binding|chemokine (C-C motif) ligand 21 binding|C-C motif chemokine 19 receptor activity|C-C motif chemokine 21 receptor activity|,10,0,0,10,-0.5,2.69,-0.2,1.46,-1.46,0.406,0,0,-1.6,0.8
ENSMUSG00000034107,ANO7,anoctamin 7,intracellular|intracellular|nucleus|endoplasmic reticulum|plasma membrane|plasma membrane|membrane|integral component of membrane|,chloride transport|chloride transport|phospholipid transport|calcium activated phosphatidylserine scrambling|calcium activated phosphatidylcholine scrambling|calcium activated galactosylceramide scrambling|chloride transmembrane transport|chloride transmembrane transport|,intracellular calcium activated chloride channel activity|phospholipid scramblase activity|,10,-0.3,1.93,10,0.2,0.422,-0.3,1.46,-1.46,0.406,0,0,-1.5,1.5
ENSMUSG00000031785,GPR56,G protein-coupled receptor 56,extracellular region|intracellular|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|glial limiting end-foot|,angiogenesis|cell adhesion|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|Rho protein signal transduction|multicellular organismal development|brain development|negative regulation of cell proliferation|vascular endothelial growth factor production|cerebral cortex radial glia guided migration|layer formation in cerebral cortex|cell differentiation|positive regulation of Rho protein signal transduction|positive regulation of cell adhesion|protein kinase C signaling|negative regulation of neuron migration|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|collagen binding|extracellular matrix binding|,10,0.5,1.88,10,-0.4,2.88,-0.3,1.45,-1.45,0.408,0,0,-1.3,1.4
ENSMUSG00000050147,F2RL3,coagulation factor II (thrombin) receptor-like 3,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|blood coagulation|hemostasis|positive regulation of release of sequestered calcium ion into cytosol|thrombin receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|thrombin receptor activity|,10,0,0,10,0.4,2.7,0.3,1.45,1.45,0.408,0,0,-1.2,1.6
ENSMUSG00000021610,CLPTM1L,CLPTM1-like,membrane|membrane|integral component of membrane|,apoptotic process|biological_process|,molecular_function|,10,-0.2,0.282,10,-0.3,1.36,-0.3,1.44,-1.44,0.409,0,0,-1.9,0.6
ENSMUSG00000039908,SLC26A11,"solute carrier family 26, member 11",lysosome|lysosomal membrane|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sulfate transport|ion transmembrane transport|,secondary active sulfate transmembrane transporter activity|anion transmembrane transporter activity|sulfate transmembrane transporter activity|anion:anion antiporter activity|,10,-0.4,2.16,10,0.9,0.0559,-0.3,1.44,-1.44,0.409,0,0,-1.3,1.7
ENSMUSG00000031617,TMEM184C,transmembrane protein 184C,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.5,2.44,0.3,1.43,1.43,0.411,0,0,-1.1,1.8
ENSMUSG00000001739,CLDN15,claudin 15,plasma membrane|tight junction|membrane|integral component of membrane|lateral plasma membrane|cell junction|,transport|ion transport|,structural molecule activity|,10,-0.7,2.42,10,-0.1,0.595,-0.3,1.43,-1.43,0.411,0,0,-1.9,0.6
ENSMUSG00000015316,SLAMF1,signaling lymphocytic activation molecule family member 1,plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|phagocytic vesicle|extracellular vesicular exosome|,regulation of vesicle fusion|lymphocyte activation|regulation of catalytic activity|,receptor activity|protein binding|,10,0.8,2.28,10,-0.1,0.113,0.8,1.42,1.42,0.413,0,0,-0.6,1.9
ENSMUSG00000033436,ARMCX2,"armadillo repeat containing, X-linked 2",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,3.4,10,-0.2,0.136,0.5,1.42,1.42,0.413,0,0,-0.6,1.8
ENSMUSG00000017167,CNTNAP1,contactin associated protein-like 1,intracellular|cell|voltage-gated potassium channel complex|membrane|integral component of membrane|axon|paranode region of axon|paranode region of axon|,protein localization to paranode region of axon|cytoskeleton organization|cell adhesion|axon cargo transport|neuronal action potential propagation|paranodal junction assembly|neuron projection development|neuron projection morphogenesis|neuromuscular process controlling posture|neuromuscular process controlling balance|,SH3 domain binding|,9,-0.6,2.57,9,0.2,0.685,0.3,1.42,1.42,0.413,0,0,-1.7,1.3
ENSMUSG00000056043,RGS9BP,regulator of G-protein signalling 9 binding protein,membrane|integral component of membrane|,visual perception|negative regulation of signal transduction|response to stimulus|detection of light stimulus involved in visual perception|,None,10,-0.6,2.93,10,0.5,1.44,-0.4,1.41,-1.41,0.414,0,0,-1.9,0.8
ENSMUSG00000029655,N4BP2L2,NEDD4 binding protein 2-like 2,nucleus|cytoplasm|transcriptional repressor complex|extracellular vesicular exosome|,negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|blastocyst development|transcription from RNA polymerase II promoter|positive regulation of hematopoietic stem cell proliferation|negative regulation of hematopoietic stem cell differentiation|,RNA polymerase II transcription corepressor activity|protein binding|enzyme binding|,10,-0.2,0.132,10,-0.4,1.53,-0.2,1.4,-1.4,0.416,0,0,-1.6,0.9
ENSMUSG00000069520,TMEM19,transmembrane protein 19,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.3,3.65,10,-0.3,1.28,1.2,1.38,1.38,0.42,0,0,-0.5,2
ENSMUSG00000063549,OLFR322,olfactory receptor 322,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.729,10,-0.4,3.07,-0.3,1.37,-1.37,0.422,0,0,-1.7,0.9
ENSMUSG00000029830,SVOPL,SV2 related protein homolog (rat)-like,membrane|integral component of membrane|,transport|transmembrane transport|,molecular_function|,10,0.7,1.25,10,-0.7,2.41,-0.4,1.37,-1.37,0.422,0,0,-1.5,1.6
ENSMUSG00000052850,TAS2R137,"taste receptor, type 2, member 137",membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|bitter taste receptor activity|,10,0.1,0.00681,10,0.5,2.71,0.3,1.36,1.36,0.424,0,0,-0.4,1.9
ENSMUSG00000032135,MCAM,melanoma cell adhesion molecule,extracellular space|nucleus|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,cell adhesion|heterophilic cell-cell adhesion|positive regulation of cell migration|,None,10,0.4,0.486,10,-0.3,1.88,-0.2,1.36,-1.36,0.424,0,0,-1.5,1.3
ENSMUSG00000027942,4933434E20RIK,RIKEN cDNA 4933434E20 gene,cellular_component|membrane|integral component of membrane|,biological_process|oxidation-reduction process|,"molecular_function|oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|coenzyme binding|",10,0.2,0.364,10,0.3,1.25,0.2,1.35,1.35,0.426,0,0,-0.8,1.6
ENSMUSG00000024486,HBEGF,heparin-binding EGF-like growth factor,extracellular region|extracellular space|extracellular space|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|,"angiogenesis|blastocyst growth|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|regulation of heart contraction|cell migration|positive regulation of cell growth|positive regulation of cell migration|wound healing, spreading of epidermal cells|positive regulation of smooth muscle cell proliferation|negative regulation of elastin biosynthetic process|positive regulation of keratinocyte migration|positive regulation of protein kinase B signaling|positive regulation of wound healing|",epidermal growth factor receptor binding|epidermal growth factor receptor binding|growth factor activity|growth factor activity|heparin binding|heparin binding|,10,-0.1,0.327,10,-0.3,1.46,-0.2,1.35,-1.35,0.426,0,0,-1.7,0.7
ENSMUSG00000026180,CXCR2,chemokine (C-X-C motif) receptor 2,intracellular|plasma membrane|cell surface|membrane|integral component of membrane|mast cell granule|,acute inflammatory response to antigenic stimulus|positive regulation of leukocyte chemotaxis|chemotaxis|chemotaxis|cellular defense response|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cell proliferation|positive regulation of cardiac muscle cell apoptotic process|neutrophil chemotaxis|receptor internalization|negative regulation of neutrophil apoptotic process|interleukin-8-mediated signaling pathway|interleukin-8-mediated signaling pathway|neutrophil activation|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of vascular permeability|positive regulation of angiogenesis|chemokine-mediated signaling pathway|chemokine-mediated signaling pathway|metanephric tubule morphogenesis|positive regulation of neutrophil chemotaxis|,signal transducer activity|interleukin-8 receptor activity|interleukin-8 receptor activity|G-protein coupled receptor activity|chemokine receptor activity|chemokine receptor activity|protein binding|C-X-C chemokine receptor activity|interleukin-8 binding|,10,0.5,3.87,10,0,0,0.5,1.35,1.35,0.426,0,0,-0.6,1.8
ENSMUSG00000030281,IL17RC,interleukin 17 receptor C,plasma membrane|membrane|integral component of membrane|,cytokine-mediated signaling pathway|positive regulation of cytokine production involved in inflammatory response|,protein binding|interleukin-17 receptor activity|,10,0.3,1.07,10,0.5,0.634,0.3,1.34,1.34,0.427,0,0,-0.4,1.9
ENSMUSG00000021749,OIT1,oncoprotein induced transcript 1,extracellular region|,negative regulation of insulin secretion|negative regulation of insulin secretion|,molecular_function|,10,0.4,2.31,10,0,0,0.3,1.34,1.34,0.427,0,0,-0.6,1.7
ENSMUSG00000035372,1810055G02RIK,RIKEN cDNA 1810055G02 gene,cellular_component|Golgi apparatus|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,2.94,10,-0.1,0.0448,0.3,1.34,1.34,0.427,0,0,-0.5,1.8
ENSMUSG00000021830,TXNDC16,thioredoxin domain containing 16,extracellular region|endoplasmic reticulum lumen|extracellular vesicular exosome|,biological_process|cell redox homeostasis|,molecular_function|,10,-0.4,1.77,10,-0.1,0.138,-0.5,1.33,-1.33,0.429,0,0,-1.7,0.7
ENSMUSG00000023017,ASIC1,acid-sensing (proton-gated) ion channel 1,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|dendritic spine|dendritic shaft|synapse|synapse|,transport|ion transport|cation transport|cation transport|sodium ion transport|calcium ion transport|memory|associative learning|response to acidity|response to acidity|monovalent inorganic cation transport|ion transmembrane transport|ion transmembrane transport|ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|negative regulation of neurotransmitter secretion|sensory perception of sour taste|calcium ion transmembrane transport|cellular response to pH|,ion channel activity|cation channel activity|cation channel activity|sodium channel activity|protein binding|monovalent inorganic cation transmembrane transporter activity|ligand-gated sodium channel activity|ion gated channel activity|ion gated channel activity|acid-sensing ion channel activity|,10,0.1,0.677,10,0.3,0.888,0.2,1.33,1.33,0.429,0,0,-0.8,1.9
ENSMUSG00000020070,RUFY2,RUN and FYVE domain-containing 2,nucleus|,None,metal ion binding|,10,0.2,1.93,10,0,0,0.2,1.32,1.32,0.431,0,0,-0.9,1.6
ENSMUSG00000036622,ATP13A2,ATPase type 13A2,lysosome|lysosomal membrane|membrane|integral component of membrane|,cation transport|,nucleotide binding|ATP binding|hydrolase activity|ATPase activity|cation-transporting ATPase activity|metal ion binding|,10,0.1,0.406,10,0.3,1.36,0.2,1.32,1.32,0.431,0,0,-0.9,1.7
ENSMUSG00000070379,OLFR402,olfactory receptor 402,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.791,10,-0.4,0.816,-0.2,1.31,-1.31,0.433,0,0,-1.4,1.2
ENSMUSG00000068740,CELSR2,"cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)",cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|,"neuron migration|cilium movement|regulation of transcription, DNA-templated|cell adhesion|homophilic cell adhesion|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|multicellular organismal development|Wnt signaling pathway|ventricular system development|neural plate anterior/posterior regionalization|regulation of cell-cell adhesion|regulation of protein localization|regulation of protein localization|cerebrospinal fluid secretion|cilium assembly|cilium assembly|dendrite morphogenesis|",signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcium ion binding|protein binding|,10,0.3,1.89,10,-0.1,0.15,0.2,1.31,1.31,0.433,0,0,-1,1.5
ENSMUSG00000000605,CLCN4-2,chloride channel 4-2,endosome|membrane|integral component of membrane|,transport|ion transport|chloride transport|transmembrane transport|chloride transmembrane transport|,nucleotide binding|ion channel activity|voltage-gated chloride channel activity|ATP binding|antiporter activity|adenyl nucleotide binding|,10,0.1,0.084,10,0.3,1.56,0.3,1.31,1.31,0.433,0,0,-0.8,1.7
ENSMUSG00000013495,TMEM175,transmembrane protein 175,lysosomal membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.155,10,-0.2,1.29,-0.2,1.29,-1.29,0.437,0,0,-1.3,1.5
ENSMUSG00000033420,ANTXR1,anthrax toxin receptor 1,plasma membrane|membrane|integral component of membrane|lamellipodium membrane|filopodium membrane|cell projection|extracellular vesicular exosome|,signal transduction|reproductive process|actin cytoskeleton reorganization|substrate adhesion-dependent cell spreading|,receptor activity|transmembrane signaling receptor activity|collagen binding|metal ion binding|actin filament binding|,10,-1.2,3.3,10,0.4,1.61,0.3,1.29,1.29,0.437,0,0,-2,1
ENSMUSG00000037341,SLC9A7,"solute carrier family 9 (sodium/hydrogen exchanger), member 7",endosome|Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|recycling endosome membrane|,transport|ion transport|cation transport|potassium ion transport|sodium ion transport|regulation of pH|sodium ion transmembrane transport|transmembrane transport|potassium ion transmembrane transport|hydrogen ion transmembrane transport|,antiporter activity|solute:proton antiporter activity|sodium:proton antiporter activity|potassium:proton antiporter activity|,9,0.8,2.14,10,0.2,0.346,0.2,1.28,1.28,0.438,0,0,-0.7,1.9
ENSMUSG00000041945,MFSD9,major facilitator superfamily domain containing 9,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|transporter activity|,10,0.1,0.507,10,0.7,2.41,0.3,1.28,1.28,0.438,0,0,-0.3,1.9
ENSMUSG00000074109,MRGPRX2,"MAS-related GPR, member X2",cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|neuropeptide binding|,10,-0.3,0.912,10,0.7,2.82,0.6,1.28,1.28,0.438,0,0,-0.8,1.9
ENSMUSG00000028832,STMN1,stathmin 1,intracellular|cytoplasm|cytosol|cytoskeleton|microtubule|membrane|extracellular vesicular exosome|,microtubule depolymerization|mitotic spindle organization|multicellular organismal development|nervous system development|axonogenesis|cell differentiation|regulation of microtubule polymerization or depolymerization|negative regulation of microtubule polymerization|positive regulation of cellular component movement|,protein binding|tubulin binding|,10,0.2,0.458,10,0.2,0.926,0.2,1.28,1.28,0.438,0,0,-1.1,1.5
ENSMUSG00000019080,MFSD3,major facilitator superfamily domain containing 3,cellular_component|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0.2,0.828,10,0.2,0.552,0.2,1.27,1.27,0.44,0,0,-1.1,1.5
ENSMUSG00000020895,TMEM107,transmembrane protein 107,cellular_component|membrane|integral component of membrane|,multicellular organismal development|neural tube patterning|cell projection organization|cilium assembly|embryonic digit morphogenesis|,molecular_function|,10,-0.1,0.0267,10,0.7,4.16,0.7,1.27,1.27,0.44,0,0,-0.5,2
ENSMUSG00000079437,TMEM179B,transmembrane protein 179B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.31,10,0.1,0.227,0.2,1.26,1.26,0.443,0,0,-0.9,1.6
ENSMUSG00000062300,PVRL2,poliovirus receptor-related 2,cell|plasma membrane|cell-cell junction|cell-cell junction|zonula adherens|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,acrosome assembly|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|positive regulation of immunoglobulin mediated immune response|cytoskeleton organization|cell adhesion|homophilic cell adhesion|homophilic cell adhesion|spermatid development|spermatid nucleus differentiation|fertilization|fusion of virus membrane with host plasma membrane|sperm mitochondrion organization|cell part morphogenesis|positive regulation of mast cell activation|susceptibility to natural killer cell mediated cytotoxicity|adhesion of symbiont to host|cilium organization|positive regulation of natural killer cell mediated cytotoxicity|coreceptor-mediated virion attachment to host cell|establishment of mitochondrion localization|susceptibility to T cell mediated cytotoxicity|,protein binding|identical protein binding|protein homodimerization activity|protein homodimerization activity|cell adhesion molecule binding|cell adhesion molecule binding|,10,0.6,0.366,10,-1.2,2.43,-0.2,1.26,-1.26,0.443,0,0,-2,0.9
ENSMUSG00000028445,ENHO,energy homeostasis associated,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.3,2.9,10,0,0,0.3,1.26,1.26,0.443,0,0,-1.3,1.4
ENSMUSG00000064210,ANO6,anoctamin 6,intracellular|plasma membrane|membrane|membrane|integral component of membrane|chloride channel complex|extracellular vesicular exosome|,dendritic cell chemotaxis|activation of blood coagulation via clotting cascade|transport|ion transport|cation transport|cation transport|chloride transport|chloride transport|chloride transport|blood coagulation|phospholipid transport|phospholipid scrambling|regulation of ion transmembrane transport|bone mineralization involved in bone maturation|regulation of anion transport|calcium activated phospholipid scrambling|calcium activated phosphatidylserine scrambling|calcium activated phosphatidylcholine scrambling|calcium activated galactosylceramide scrambling|phosphatidylserine exposure on blood platelet|chloride transmembrane transport|chloride transmembrane transport|positive regulation of endothelial cell apoptotic process|,calcium activated cation channel activity|calcium activated cation channel activity|intracellular calcium activated chloride channel activity|intracellular calcium activated chloride channel activity|voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|phospholipid scramblase activity|phospholipid scramblase activity|protein homodimerization activity|,10,-0.2,0.595,10,-0.2,0.751,-0.2,1.24,-1.24,0.447,0,0,-1.7,0.8
ENSMUSG00000050150,SLC9B1,"solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1",cellular_component|membrane|integral component of membrane|,transport|cation transport|biological_process|transmembrane transport|,molecular_function|solute:proton antiporter activity|,10,0.2,0.807,10,0.2,0.542,0.2,1.24,1.24,0.447,0,0,-1.4,1.3
ENSMUSG00000044367,SLC16A13,"solute carrier family 16 (monocarboxylic acid transporters), member 13",Golgi apparatus|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,9,-0.3,0.794,9,-0.4,0.563,-0.3,1.23,-1.23,0.449,0,0,-1.8,0.8
ENSMUSG00000057234,METTL15,methyltransferase like 15,cellular_component|,methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,0.565,10,-0.4,1.3,-0.4,1.23,-1.23,0.449,0,0,-1.5,1
ENSMUSG00000021565,SLC6A19,"solute carrier family 6 (neurotransmitter transporter), member 19",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|brush border membrane|extracellular vesicular exosome|,amino acid transmembrane transport|transport|neurotransmitter transport|amino acid transport|neutral amino acid transport|,neurotransmitter:sodium symporter activity|protein binding|neutral amino acid transmembrane transporter activity|symporter activity|,10,-0.3,2.18,10,0.1,0.151,-0.3,1.22,-1.22,0.451,0,0,-1.3,1.7
ENSMUSG00000031791,TMEM38A,transmembrane protein 38A,nucleus|membrane|integral component of membrane|sarcoplasmic reticulum|extracellular vesicular exosome|,transport|ion transport|potassium ion transport|monovalent inorganic cation transport|potassium ion transmembrane transport|,cation channel activity|potassium channel activity|calcium-activated potassium channel activity|,10,-0.1,0.23,10,-0.2,1.21,-0.2,1.22,-1.22,0.451,0,0,-1.6,1.1
ENSMUSG00000034258,MFSD7C,major facilitator superfamily domain containing 7C,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|heme transport|transmembrane transport|,heme transporter activity|heme binding|,10,-0.2,1.21,10,-0.1,0.158,-0.2,1.22,-1.22,0.451,0,0,-1.6,1
ENSMUSG00000021499,CATSPER3,"cation channel, sperm associated 3",acrosomal vesicle|endoplasmic reticulum|plasma membrane|cilium|membrane|integral component of membrane|CatSper complex|cell projection|,transport|ion transport|sodium ion transport|calcium ion transport|multicellular organismal development|spermatogenesis|cell differentiation|sperm motility|regulation of ion transmembrane transport|sperm capacitation|transmembrane transport|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|calcium activated cation channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|,10,-0.6,2.47,10,0.2,0.363,-0.3,1.21,-1.21,0.453,0,0,-1.8,0.7
ENSMUSG00000030474,SIGLECE,sialic acid binding Ig-like lectin E,membrane|integral component of membrane|,cell adhesion|intracellular signal transduction|,receptor activity|receptor signaling protein activity|monosaccharide binding|,10,0.2,0.319,10,0.4,1.24,0.3,1.21,1.21,0.453,0,0,-1.2,1.5
ENSMUSG00000032012,PVRL1,poliovirus receptor-related 1,plasma membrane|cell-cell adherens junction|cell-cell adherens junction|membrane|integral component of membrane|catenin complex|cell junction|axon|growth cone membrane|neuron projection|intracellular membrane-bounded organelle|synapse|,lens morphogenesis in camera-type eye|desmosome organization|iron ion transport|cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|axon guidance|viral process|single organismal cell-cell adhesion|viral entry into host cell|camera-type eye morphogenesis|regulation of synapse assembly|retina development in camera-type eye|enamel mineralization|,receptor activity|protein binding|carbohydrate binding|protein homodimerization activity|virion binding|protein heterodimerization activity|cell adhesion molecule binding|,10,0.2,0.611,10,0.7,1.66,0.2,1.21,1.21,0.453,0,0,-0.9,1.9
ENSMUSG00000021384,SUSD3,sushi domain containing 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0624,10,0.4,2.25,0.3,1.21,1.21,0.453,0,0,-0.6,1.8
ENSMUSG00000020251,GLT8D2,glycosyltransferase 8 domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.3,0.799,10,-0.3,0.506,-0.3,1.2,-1.2,0.456,0,0,-1.9,0.4
ENSMUSG00000005649,CABP5,calcium binding protein 5,cytoplasm|cytosol|,None,calcium ion binding|metal ion binding|,10,-0.1,0.247,10,0.4,1.27,0.3,1.2,1.2,0.456,0,0,-0.7,1.9
ENSMUSG00000026616,CR2,complement receptor 2,external side of plasma membrane|membrane|integral component of membrane|receptor complex|extracellular vesicular exosome|,"immune system process|complement receptor mediated signaling pathway|complement activation, classical pathway|B cell differentiation|B cell proliferation|B cell activation|innate immune response|",complement binding|DNA binding|receptor activity|complement receptor activity|protein binding|protein homodimerization activity|,10,0.3,0.735,10,0.2,0.65,0.3,1.19,1.19,0.458,0,0,-0.7,1.7
ENSMUSG00000024366,GFRA3,glial cell line derived neurotrophic factor family receptor alpha 3,cytoplasm|plasma membrane|external side of plasma membrane|membrane|anchored component of membrane|intracellular membrane-bounded organelle|,neuron migration|signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|axon guidance|sympathetic nervous system development|neuron development|,receptor activity|protein binding|axon guidance receptor activity|coreceptor activity|,10,0.8,2.71,10,0.2,0.193,0.7,1.19,1.19,0.458,0,0,-0.5,2
ENSMUSG00000055862,IZUMO4,IZUMO family member 4,extracellular region|nucleus|,biological_process|,molecular_function|,10,-0.2,0.953,10,-0.2,0.338,-0.2,1.19,-1.19,0.458,0,0,-1.7,0.8
ENSMUSG00000035785,CMTM2B,CKLF-like MARVEL transmembrane domain containing 2B,extracellular space|nucleus|membrane|integral component of membrane|,chemotaxis|,cytokine activity|,10,-0.3,1.39,10,-0.1,0.0424,-0.4,1.18,-1.18,0.46,0,0,-1.6,1
ENSMUSG00000030468,SIGLECG,sialic acid binding Ig-like lectin G,membrane|integral component of membrane|,hematopoietic progenitor cell differentiation|,protein binding|,10,0.4,1.17,10,0.1,0.542,0.3,1.18,1.18,0.46,0,0,-1.2,1.6
ENSMUSG00000025920,STAU2,staufen (RNA binding protein) homolog 2 (Drosophila),nucleus|cytoplasm|endoplasmic reticulum|microtubule|membrane|,transport|,RNA binding|double-stranded RNA binding|poly(A) RNA binding|,10,0.6,2.13,10,-0.4,1.6,-0.3,1.18,-1.18,0.46,0,0,-1.5,1.4
ENSMUSG00000049791,FZD4,frizzled homolog 4 (Drosophila),cytoplasm|plasma membrane|plasma membrane|plasma membrane|cell-cell junction|cell surface|membrane|integral component of membrane|cell projection|extracellular vesicular exosome|,"luteinization|blood vessel development|vasculogenesis|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|Wnt signaling pathway, calcium modulating pathway|multicellular organismal development|sensory perception of sound|embryo development|negative regulation of cell-substrate adhesion|negative regulation of cell-substrate adhesion|Wnt signaling pathway|regulation of vascular endothelial growth factor receptor signaling pathway|locomotion involved in locomotory behavior|substrate adhesion-dependent cell spreading|extracellular matrix-cell signaling|progesterone secretion|positive regulation of JUN kinase activity|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|canonical Wnt signaling pathway|canonical Wnt signaling pathway|canonical Wnt signaling pathway|retina vasculature morphogenesis in camera-type eye|retina vasculature morphogenesis in camera-type eye|retina vasculature morphogenesis in camera-type eye|cerebellum vasculature morphogenesis|retinal blood vessel morphogenesis|",signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|Wnt-protein binding|Wnt-protein binding|cytokine binding|cytokine binding|PDZ domain binding|PDZ domain binding|ubiquitin protein ligase binding|protein homodimerization activity|Wnt-activated receptor activity|Wnt-activated receptor activity|protein heterodimerization activity|,10,-0.3,1.85,9,0.7,3.72,-0.3,1.18,-1.18,0.46,0,0,-1,1.8
ENSMUSG00000049872,FAM26E,"family with sequence similarity 26, member E",membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|biological_process|,molecular_function|,10,-0.6,0.588,10,-0.3,0.997,-0.3,1.18,-1.18,0.46,0,0,-1.9,0.5
ENSMUSG00000042641,RGSL1,regulator of G-protein signaling like 1,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.949,10,0.3,0.731,-0.2,1.17,-1.17,0.462,0,0,-1.2,1.4
ENSMUSG00000094924,CR2,complement receptor 2,external side of plasma membrane|membrane|integral component of membrane|receptor complex|extracellular vesicular exosome|,"immune system process|complement receptor mediated signaling pathway|complement activation, classical pathway|B cell differentiation|B cell proliferation|B cell activation|innate immune response|",complement binding|DNA binding|receptor activity|complement receptor activity|protein binding|protein homodimerization activity|,10,-0.7,1.1,10,0.9,4.05,0.8,1.17,1.17,0.462,0,0,-1.2,2
ENSMUSG00000068105,TNFRSF13C,"tumor necrosis factor receptor superfamily, member 13c",external side of plasma membrane|membrane|integral component of membrane|,B cell homeostasis|immune system process|positive regulation of germinal center formation|positive regulation of B cell proliferation|T cell costimulation|T cell costimulation|B cell costimulation|positive regulation of T cell proliferation|positive regulation of T cell proliferation|positive regulation of interferon-gamma biosynthetic process|regulation of immune response|,None,10,0.9,1.4,10,0.2,0.292,0.2,1.17,1.17,0.462,0,0,-1.1,1.9
ENSMUSG00000071150,TAS2R121,"taste receptor, type 2, member 121",cellular_component|plasma membrane|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytokinesis|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|bitter taste receptor activity|,10,0,0,10,-0.3,1.96,-0.3,1.17,-1.17,0.462,0,0,-1.7,0.8
ENSMUSG00000038578,SUSD1,sushi domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.39,10,0.2,0.642,-0.3,1.17,-1.17,0.462,0,0,-1.7,0.8
ENSMUSG00000041143,TMCO4,transmembrane and coiled-coil domains 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.318,10,0.2,0.93,0.2,1.15,1.15,0.467,0,0,-0.8,1.7
ENSMUSG00000051790,NLGN2,neuroligin 2,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|excitatory synapse|inhibitory synapse|inhibitory synapse|,"thigmotaxis|regulation of respiratory gaseous exchange by neurological system process|cell adhesion|neuron cell-cell adhesion|synapse assembly|synapse assembly|jump response|sensory perception of pain|positive regulation of synaptic transmission, GABAergic|social behavior|protein localization to synapse|locomotory exploration behavior|regulation of synaptic transmission|synapse organization|neuromuscular process controlling balance|positive regulation of synapse assembly|positive regulation of synaptic transmission, glutamatergic|terminal button organization|postsynaptic membrane assembly|presynaptic membrane assembly|presynaptic membrane assembly|presynaptic membrane assembly|gephyrin clustering|postsynaptic density protein 95 clustering|positive regulation of inhibitory postsynaptic membrane potential|positive regulation of inhibitory postsynaptic membrane potential|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|positive regulation of excitatory postsynaptic membrane potential|",receptor activity|protein binding|neurexin family protein binding|neurexin family protein binding|cell adhesion molecule binding|,10,-0.5,2.48,10,0.1,0.225,-0.4,1.15,-1.15,0.467,0,0,-1.8,0.8
ENSMUSG00000043531,SORCS1,VPS10 domain receptor protein SORCS 1,membrane|integral component of membrane|,None,None,10,-0.1,0.292,10,-0.2,0.978,-0.2,1.15,-1.15,0.467,0,0,-1.6,1
ENSMUSG00000028460,SIT1,suppression inducing transmembrane adaptor 1,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,immune system process|regulation of T cell activation|,kinase binding|,10,0.3,1.12,10,-1,1.31,-0.3,1.14,-1.14,0.469,0,0,-1.9,0.8
ENSMUSG00000079580,TMEM217,transmembrane protein 217,cellular_component|,biological_process|,molecular_function|,10,0.1,0.203,10,0.2,1.22,0.2,1.14,1.14,0.469,0,0,-0.9,1.7
ENSMUSG00000005947,ITGAE,"integrin alpha E, epithelial-associated",integrin complex|external side of plasma membrane|membrane|integral component of membrane|,cell adhesion|integrin-mediated signaling pathway|,metal ion binding|,10,1.4,3.44,10,0.2,0.467,1.3,1.14,1.14,0.469,0,0,-0.3,2
ENSMUSG00000094152,SLC6A16,"solute carrier family 6, member 16",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|symporter activity|,10,-0.3,1.14,10,0.2,0.366,-0.3,1.14,-1.14,0.469,0,0,-1.6,1.1
ENSMUSG00000043015,TMEM194B,transmembrane protein 194B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.983,10,0.2,0.236,0.2,1.13,1.13,0.471,0,0,-1,1.6
ENSMUSG00000045435,TMEM60,transmembrane protein 60,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.53,10,0.1,0.0813,-0.5,1.13,-1.13,0.471,0,0,-1.8,1.1
ENSMUSG00000024232,BAMBI,BMP and activin membrane-bound inhibitor,cytoplasm|plasma membrane|membrane|integral component of membrane|,"transforming growth factor beta receptor signaling pathway|positive regulation of cell proliferation|regulation of cell shape|positive regulation of epithelial to mesenchymal transition|cell migration|negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of protein binding|positive regulation of catenin import into nucleus|positive regulation of transcription, DNA-templated|positive regulation of canonical Wnt signaling pathway|",frizzled binding|,10,0.6,2.34,10,-0.2,0.225,0.4,1.13,1.13,0.471,0,0,-0.7,1.8
ENSMUSG00000027994,CCDC109B,coiled-coil domain containing 109B,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|intrinsic component of membrane|integral component of mitochondrial inner membrane|calcium channel complex|uniplex complex|,transport|ion transport|calcium ion transport|mitochondrial calcium ion transport|mitochondrial calcium ion homeostasis|,protein binding|calcium channel inhibitor activity|,10,1.3,3.78,9,-0.3,0.319,0.3,1.13,1.13,0.471,0,0,-0.8,2
ENSMUSG00000009035,TMEM184B,transmembrane protein 184b,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.2,10,-0.4,1.57,0.2,1.12,1.12,0.473,0,0,-1,2
ENSMUSG00000038522,AI317395,expressed sequence AI317395,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|biological_process|carbohydrate transport|transmembrane transport|,molecular_function|symporter activity|,10,0,0,10,-0.4,1.76,-0.4,1.1,-1.1,0.477,0,0,-1.7,0.7
ENSMUSG00000050288,FZD2,frizzled homolog 2 (Drosophila),cytoplasm|cytoplasm|plasma membrane|membrane|integral component of membrane|neuron projection membrane|apical part of cell|,"vasculature development|membranous septum morphogenesis|muscular septum morphogenesis|outflow tract morphogenesis|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|positive regulation of cytosolic calcium ion concentration|Wnt signaling pathway, calcium modulating pathway|Wnt signaling pathway, calcium modulating pathway|cell-cell signaling|multicellular organismal development|axonogenesis|brain development|sensory perception of smell|gonad development|Wnt signaling pathway|positive regulation of cGMP metabolic process|epithelial cell differentiation|epithelial cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of sequence-specific DNA binding transcription factor activity|hard palate development|hard palate development|canonical Wnt signaling pathway|canonical Wnt signaling pathway|inner ear receptor cell development|ventricular septum morphogenesis|cochlea morphogenesis|planar cell polarity pathway involved in neural tube closure|",signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|Wnt-protein binding|PDZ domain binding|PDZ domain binding|identical protein binding|Wnt-activated receptor activity|Wnt-activated receptor activity|protein heterodimerization activity|,10,-0.2,1.08,10,0.6,1.18,-0.2,1.1,-1.1,0.477,0,0,-1,1.8
ENSMUSG00000026678,RGS5,regulator of G-protein signaling 5,cytoplasm|cytoplasm|plasma membrane|membrane|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|negative regulation of G-protein coupled receptor protein signaling pathway|,GTPase activator activity|GTPase activator activity|,10,0.1,0.0551,10,0.4,2.09,0.2,1.1,1.1,0.477,0,0,-0.6,1.8
ENSMUSG00000040372,GPR63,G protein-coupled receptor 63,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0.3,1.95,0.2,1.09,1.09,0.48,0,0,-1,1.6
ENSMUSG00000000792,SLC5A5,"solute carrier family 5 (sodium iodide symporter), member 5",nucleus|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|anion transport|iodide transport|sodium ion transmembrane transport|sodium ion transmembrane transport|transmembrane transport|,transporter activity|sodium:iodide symporter activity|sodium:iodide symporter activity|iodide transmembrane transporter activity|symporter activity|,10,-0.2,1.21,10,0,0,-0.2,1.08,-1.08,0.482,0,0,-1.8,0.6
ENSMUSG00000049556,LINGO1,leucine rich repeat and Ig domain containing 1,intracellular|plasma membrane|membrane|integral component of membrane|,central nervous system neuron development|central nervous system neuron development|neuron projection development|protein kinase B signaling|negative regulation of oligodendrocyte differentiation|,epidermal growth factor receptor binding|protein binding|,10,0.6,0.882,10,0.3,0.509,0.3,1.08,1.08,0.482,0,0,-0.9,1.8
ENSMUSG00000040899,CCR6,chemokine (C-C motif) receptor 6,plasma membrane|cell surface|membrane|integral component of membrane|,chemotaxis|immune response|signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|,10,0.2,0.194,10,0.2,0.953,0.2,1.06,1.06,0.486,0,0,-0.9,1.7
ENSMUSG00000042535,GTPBP1,GTP binding protein 1,cytoplasmic exosome (RNase complex)|cytoplasm|cytosol|membrane|,GTP catabolic process|positive regulation of mRNA catabolic process|,nucleotide binding|GTPase activity|GTP binding|poly(A) RNA binding|,10,-0.4,2.44,9,0.8,0.391,-0.3,1.06,-1.06,0.486,0,0,-1.4,1.6
ENSMUSG00000032412,ATP1B3,"ATPase, Na+/K+ transporting, beta 3 polypeptide",cytoplasm|plasma membrane|sodium:potassium-exchanging ATPase complex|caveola|membrane|integral component of membrane|extracellular vesicular exosome|,ATP catabolic process|transport|ion transport|potassium ion transport|sodium ion transport|metal ion transport|sodium ion transmembrane transport|potassium ion transmembrane transport|,sodium:potassium-exchanging ATPase activity|protein binding|,5,-0.7,0.567,6,1.1,1.39,-0.8,1.05,-1.05,0.488,0,0,-1.8,1.7
ENSMUSG00000037996,SLC24A2,"solute carrier family 24 (sodium/potassium/calcium exchanger), member 2",membrane|integral component of membrane|intrinsic component of plasma membrane|,calcium ion transport|cellular calcium ion homeostasis|learning|memory|ion transmembrane transport|sodium ion transmembrane transport|long-term synaptic potentiation|long term synaptic depression|calcium ion transmembrane transport|calcium ion transmembrane transport|potassium ion transmembrane transport|,"calcium channel activity|calcium ion binding|calcium, potassium:sodium antiporter activity|nickel cation binding|manganese ion binding|potassium ion binding|sodium ion binding|cadmium ion binding|protein dimerization activity|",10,0.2,0.165,10,0.8,1.32,0.7,1.05,1.05,0.488,0,0,-0.3,1.9
ENSMUSG00000025735,RHBDL1,"rhomboid, veinlet-like 1 (Drosophila)",membrane|integral component of membrane|,proteolysis|biological_process|,serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,9,0.1,0.139,9,0.5,1.81,0.4,1.05,1.05,0.488,0,0,-1.1,1.7
ENSMUSG00000034908,SIDT2,"SID1 transmembrane family, member 2",lysosome|lysosomal membrane|lysosomal membrane|membrane|integral component of membrane|,cell morphogenesis|type B pancreatic cell development|response to glucose|dsRNA transport|glucose homeostasis|type B pancreatic cell proliferation|regulation of insulin secretion involved in cellular response to glucose stimulus|,molecular_function|RNA transmembrane transporter activity|,10,0.1,0.319,10,-0.6,2.3,-0.5,1.03,-1.03,0.493,0,0,-1.9,0.7
ENSMUSG00000031962,CDH15,cadherin 15,plasma membrane|caveola|membrane|integral component of membrane|neuromuscular junction|,cell adhesion|homophilic cell adhesion|,calcium ion binding|protein binding|metal ion binding|,10,0.2,0.766,10,-0.3,2.54,-0.2,1.03,-1.03,0.493,0,0,-1.8,0.8
ENSMUSG00000045114,PRRT2,proline-rich transmembrane protein 2,plasma membrane|membrane|integral component of membrane|cell junction|synapse|,response to biotic stimulus|neuromuscular process controlling posture|,molecular_function|,10,-0.3,1.31,10,0.6,2.19,-0.3,1.03,-1.03,0.493,0,0,-1.7,1.4
ENSMUSG00000038497,TMCO3,transmembrane and coiled-coil domains 3,cellular_component|membrane|integral component of membrane|,transport|ion transport|cation transport|biological_process|transmembrane transport|,molecular_function|antiporter activity|solute:proton antiporter activity|,10,0,0,10,-0.8,2.35,-0.3,1.03,-1.03,0.493,0,0,-1.8,0.6
ENSMUSG00000054871,TMEM158,transmembrane protein 158,cellular_component|membrane|integral component of membrane|,biological_process|,protein binding|peptide binding|,10,0.2,0.631,10,0.2,0.461,0.2,1,1,0.5,0,0,-0.9,1.7
ENSMUSG00000053897,SLC39A8,"solute carrier family 39 (metal ion transporter), member 8",plasma membrane|membrane|integral component of membrane|organelle membrane|,transport|ion transport|zinc ion transport|metal ion transport|transmembrane transport|cadmium ion transmembrane transport|,metal ion transmembrane transporter activity|,10,0.1,0.0854,10,0.3,1.5,0.2,0.998,0.998,0.501,0,0,-0.8,1.7
ENSMUSG00000039691,TSPAN10,tetraspanin 10,membrane|integral component of membrane|,protein maturation|establishment of protein localization to organelle|,enzyme binding|enzyme binding|,10,0.1,0.0698,10,0.3,1.4,0.2,0.997,0.997,0.501,0,0,-1.2,1.5
ENSMUSG00000066720,CLDN9,claudin 9,plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,cell-cell junction organization|,structural molecule activity|,10,0.2,1.11,10,0.1,0.157,0.2,0.995,0.995,0.502,0,0,-0.9,1.7
ENSMUSG00000070287,SLC35G2,"solute carrier family 35, member G2",Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,0.9,10,0.1,0.222,0.2,0.991,0.991,0.503,0,0,-0.8,1.7
ENSMUSG00000046589,LRRC8E,"leucine rich repeat containing 8 family, member E",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.2,1.24,10,-0.1,0.154,0.2,0.981,0.981,0.505,0,0,-1,1.6
ENSMUSG00000042066,TMCC2,transmembrane and coiled-coil domains 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.1,0.152,9,0.6,3.69,0.6,0.98,0.98,0.505,0,0,-0.9,1.9
ENSMUSG00000039155,CDH26,cadherin-like 26,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|biological_process|,calcium ion binding|metal ion binding|,10,0,0,10,-1.4,3.64,0.5,0.98,0.98,0.505,0,0,-2,1.2
ENSMUSG00000070547,MRGPRB1,"MAS-related GPR, member B1",cellular_component|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|neuropeptide binding|,10,-0.2,0.357,10,-0.2,0.705,-0.2,0.977,-0.977,0.506,0,0,-1.7,0.9
ENSMUSG00000038147,CD84,CD84 antigen,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|,receptor activity|,10,0,0,10,-0.5,2.22,-0.2,0.975,-0.975,0.507,0,0,-1.7,0.9
ENSMUSG00000024958,GPR137,G protein-coupled receptor 137,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,2.64,10,0.1,0.248,-0.3,0.967,-0.967,0.509,0,0,-1.6,1
ENSMUSG00000064310,ZPLD1,zona pellucida like domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.892,10,-0.2,0.138,-0.2,0.951,-0.951,0.513,0,0,-1.6,1
ENSMUSG00000004945,TMEM242,transmembrane protein 242,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.4,1.25,9,0.3,0.666,-0.6,0.949,-0.949,0.513,0,0,-2,0.8
ENSMUSG00000029219,SLC10A4,"solute carrier family 10 (sodium/bile acid cotransporter family), member 4",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|adult behavior|response to drug|,molecular_function|bile acid:sodium symporter activity|symporter activity|,10,-0.5,2.56,10,0.4,1.82,0.3,0.941,0.941,0.515,0,0,-1.6,1.1
ENSMUSG00000008153,CLSTN3,calsyntenin 3,endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|postsynaptic membrane|postsynaptic membrane|extracellular vesicular exosome|,"cell adhesion|homophilic cell adhesion|synapse assembly|synapse assembly|synaptic transmission, glutamatergic|synaptic transmission, GABAergic|",calcium ion binding|protein binding|,10,0.7,2.61,10,-0.1,0.154,0.6,0.932,0.932,0.518,0,0,-0.8,1.9
ENSMUSG00000039953,CLSTN1,calsyntenin 1,extracellular region|nucleus|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|cell junction|cell projection|synapse|postsynaptic membrane|extracellular vesicular exosome|,cellular calcium ion homeostasis|cell adhesion|homophilic cell adhesion|synaptic transmission|,beta-amyloid binding|calcium ion binding|protein binding|kinesin binding|X11-like protein binding|,10,0.4,1.41,10,0.1,0.137,0.2,0.924,0.924,0.519,0,0,-1.1,1.6
ENSMUSG00000006463,ZDHHC24,"zinc finger, DHHC domain containing 24",cellular_component|membrane|integral component of membrane|,biological_process|,"molecular_function|zinc ion binding|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.1,0.303,10,0.2,0.697,0.2,0.917,0.917,0.521,0,0,-1.1,1.6
ENSMUSG00000036862,DCHS1,dachsous 1 (Drosophila),intracellular|plasma membrane|membrane|integral component of membrane|apical part of cell|,branching involved in ureteric bud morphogenesis|establishment of planar polarity|kidney development|heart morphogenesis|cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|neural tube development|neurogenesis|hippo signaling|post-anal tail morphogenesis|ossification involved in bone maturation|digestive tract development|cochlea development|,molecular_function|calcium ion binding|,10,0,0,10,-0.3,2.07,-0.2,0.913,-0.913,0.522,0,0,-1.6,1.1
ENSMUSG00000017417,PLXDC1,plexin domain containing 1,cytoplasm|plasma membrane|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|dendrite|neuronal cell body|receptor complex|,multicellular organismal development|,receptor activity|protein binding|,10,0.4,1.56,10,-0.1,0.17,0.2,0.912,0.912,0.522,0,0,-1.2,1.5
ENSMUSG00000044017,GPR133,G protein-coupled receptor 133,plasma membrane|membrane|integral component of membrane|,cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0.1,0.043,10,0.3,1.04,0.3,0.906,0.906,0.524,0,0,-0.8,1.9
ENSMUSG00000022035,CCDC25,coiled-coil domain containing 25,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.5,1.35,10,-0.1,0.252,-0.2,0.9,-0.9,0.525,0,0,-1.9,0.7
ENSMUSG00000020399,HAVCR2,hepatitis A virus cellular receptor 2,membrane|integral component of membrane|extracellular vesicular exosome|,None,protein binding|,10,0.2,0.155,10,-0.4,1.09,-0.2,0.899,-0.899,0.526,0,0,-1.8,0.9
ENSMUSG00000003341,ATP8B3,"ATPase, class I, type 8B, member 3",acrosomal vesicle|endoplasmic reticulum|membrane|integral component of membrane|cytoplasmic vesicle|,ATP catabolic process|transport|cation transport|lipid transport|binding of sperm to zona pellucida|phospholipid transport|phospholipid translocation|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,9,-0.1,0.231,10,-0.3,0.843,-0.2,0.882,-0.882,0.53,0,0,-1.5,1.4
ENSMUSG00000030762,AQP8,aquaporin 8,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|apical part of cell|intracellular canaliculus|,transport|water transport|water transport|water transport|canalicular bile acid transport|transmembrane transport|,transporter activity|water channel activity|water channel activity|,10,0.1,0.209,10,0.6,1.7,0.2,0.882,0.882,0.53,0,0,-0.5,2
ENSMUSG00000047953,GP5,glycoprotein 5 (platelet),cell surface|,cell-matrix adhesion|negative regulation of platelet activation|,collagen binding|,10,0,0,10,0.4,2.21,0.2,0.875,0.875,0.532,0,0,-1,1.6
ENSMUSG00000025404,R3HDM2,R3H domain containing 2,cellular_component|nucleus|,biological_process|,nucleic acid binding|poly(A) RNA binding|,10,0.3,0.601,10,0.2,0.498,0.2,0.871,0.871,0.533,0,0,-1.3,1.5
ENSMUSG00000030847,BAG3,BCL2-associated athanogene 3,cytoplasm|cytosol|plasma membrane|Z disc|neuron projection|,apoptotic process|extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of striated muscle cell apoptotic process|protein stabilization|cellular response to mechanical stimulus|extrinsic apoptotic signaling pathway in absence of ligand|,protein binding|protein complex binding|protein complex binding|chaperone binding|,10,0.2,1.42,10,-0.1,0.339,0.2,0.859,0.859,0.536,0,0,-0.8,1.9
ENSMUSG00000027546,ATP9A,"ATPase, class II, type 9A",endosome|early endosome|Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|perinuclear region of cytoplasm|recycling endosome|,cation transport|phospholipid transport|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,-0.3,1.51,10,0.2,0.42,-0.2,0.848,-0.848,0.539,0,0,-1.5,1.1
ENSMUSG00000020212,MDM1,transformed mouse 3T3 cell double minute 1,nucleus|,retina development in camera-type eye|,None,10,0.2,0.674,10,0.2,0.247,0.2,0.846,0.846,0.54,0,0,-1,1.7
ENSMUSG00000050530,FAM171A1,"family with sequence similarity 171, member A1",extracellular vesicular exosome|,biological_process|,molecular_function|,9,-0.4,1.79,10,0.1,0.393,-0.2,0.844,-0.844,0.54,0,0,-1.5,1.2
ENSMUSG00000044328,TRP53I13,transformation related protein 53 inducible protein 13,cellular_component|cytoplasm|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.2,1.87,10,0.2,0.123,0.2,0.84,0.84,0.541,0,0,-0.8,2
ENSMUSG00000038119,CDON,cell adhesion molecule-related/down-regulated by oncogenes,plasma membrane|integral component of plasma membrane|cell surface|cell surface|membrane|integral component of membrane|,cell fate specification|positive regulation of protein phosphorylation|lens development in camera-type eye|cell adhesion|smoothened signaling pathway|smoothened signaling pathway|myoblast fusion|anterior/posterior pattern specification|embryonic body morphogenesis|embryonic body morphogenesis|skeletal muscle satellite cell differentiation|regulation of striated muscle tissue development|single organismal cell-cell adhesion|cerebral cortex development|positive regulation of MAPK cascade|positive regulation of MAPK cascade|regulation of protein heterodimerization activity|positive regulation of myoblast differentiation|regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of transcription from RNA polymerase II promoter|embryonic morphogenesis|positive regulation of skeletal muscle tissue development|positive regulation of small GTPase mediated signal transduction|striated muscle cell differentiation|embryonic retina morphogenesis in camera-type eye|positive regulation of neural precursor cell proliferation|,protein binding|,10,-0.5,1.17,10,-0.1,0.493,-0.2,0.839,-0.839,0.541,0,0,-2,0.5
ENSMUSG00000071537,KLRG2,"killer cell lectin-like receptor subfamily G, member 2",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|carbohydrate binding|,10,-0.2,0.485,10,-0.2,0.429,-0.2,0.838,-0.838,0.542,0,0,-1.6,1
ENSMUSG00000025227,TMEM180,transmembrane protein 180,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.383,10,0.5,2.38,0.2,0.837,0.837,0.542,0,0,-1.1,1.6
ENSMUSG00000035776,CD99L2,CD99 antigen-like 2,plasma membrane|membrane|integral component of membrane|cell junction|,cell adhesion|,None,10,0,0,10,0.4,2.58,0.3,0.837,0.837,0.542,0,0,-1,1.6
ENSMUSG00000008590,HTR3B,5-hydroxytryptamine (serotonin) receptor 3B,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|neuronal cell body|postsynaptic membrane|,transport|ion transport|cation transport|serotonin receptor signaling pathway|serotonin receptor signaling pathway|serotonin receptor signaling pathway|ion transmembrane transport|,serotonin receptor activity|serotonin receptor activity|serotonin receptor activity|extracellular ligand-gated ion channel activity|serotonin-activated cation-selective channel activity|serotonin-activated cation-selective channel activity|ligand-gated ion channel activity|,10,0.3,0.411,10,-1.2,3,-0.3,0.835,-0.835,0.543,0,0,-2,1.2
ENSMUSG00000038623,TM6SF1,transmembrane 6 superfamily member 1,membrane|integral component of membrane|,None,None,10,0,0,10,0.3,1.53,0.2,0.833,0.833,0.543,0,0,-0.9,1.8
ENSMUSG00000031684,SLC10A7,"solute carrier family 10 (sodium/bile acid cotransporter family), member 7",cellular_component|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|biological_process|,molecular_function|symporter activity|,9,0.5,0.629,9,0.2,0.658,0.3,0.828,0.828,0.545,0,0,-0.6,1.9
ENSMUSG00000068566,MYADM,myeloid-associated differentiation marker,ruffle|plasma membrane|cell-cell junction|membrane|integral component of membrane|cortical actin cytoskeleton|membrane raft|extracellular vesicular exosome|,negative regulation of protein phosphorylation|negative regulation of gene expression|positive regulation of cell migration|negative regulation of actin filament polymerization|membrane raft organization|negative regulation of heterotypic cell-cell adhesion|establishment of endothelial barrier|protein targeting to plasma membrane|negative regulation of protein kinase C signaling|positive regulation of substrate adhesion-dependent cell spreading|,None,10,-0.1,0.136,10,-0.3,1.18,-0.2,0.826,-0.826,0.545,0,0,-1.6,1.1
ENSMUSG00000045576,ST7L,suppression of tumorigenicity 7-like,cellular_component|membrane|integral component of membrane|,extracellular matrix organization|negative regulation of cell growth|regulation of cell differentiation|,molecular_function|,10,-0.1,0.478,10,-0.1,0.423,-0.1,0.826,-0.826,0.545,0,0,-1.8,0.9
ENSMUSG00000007107,ATP1A4,"ATPase, Na+/K+ transporting, alpha 4 polypeptide",cellular_component|plasma membrane|membrane|integral component of membrane|,ATP catabolic process|ATP biosynthetic process|transport|ion transport|cation transport|potassium ion transport|sodium ion transport|spermatogenesis|fertilization|monovalent inorganic cation transport|sperm motility|sperm motility|regulation of cellular pH|sodium ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|potassium ion transmembrane transport|,"nucleotide binding|sodium:potassium-exchanging ATPase activity|sodium:potassium-exchanging ATPase activity|sodium:potassium-exchanging ATPase activity|ATP binding|monovalent inorganic cation transmembrane transporter activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|cation-transporting ATPase activity|metal ion binding|",10,0.2,0.211,10,0.3,0.812,0.2,0.826,0.826,0.545,0,0,-0.7,1.8
ENSMUSG00000027075,SLC43A1,"solute carrier family 43, member 1",membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|neutral amino acid transport|L-amino acid transport|transmembrane transport|L-alpha-amino acid transmembrane transport|,neutral amino acid transmembrane transporter activity|L-amino acid transmembrane transporter activity|,10,0,0,10,0.4,1.77,0.2,0.825,0.825,0.545,0,0,-0.7,1.8
ENSMUSG00000032046,ABHD12,abhydrolase domain containing 12,membrane|integral component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,phosphatidylserine catabolic process|adult walking behavior|response to auditory stimulus|,hydrolase activity|acylglycerol lipase activity|,10,0.5,2.77,10,-0.2,0.447,0.4,0.824,0.824,0.546,0,0,-0.8,1.8
ENSMUSG00000058441,PANX2,pannexin 2,cytoplasm|plasma membrane|gap junction|membrane|integral component of membrane|cell junction|,response to ischemia|transport|ion transport|cell-cell signaling|transmembrane transport|transmembrane transport|,gap junction channel activity|channel activity|protein heterodimerization activity|,10,0.2,0.762,10,-0.2,0.525,0.2,0.822,0.822,0.546,0,0,-0.9,1.8
ENSMUSG00000044364,TMEM74B,transmembrane protein 74B,cellular_component|,biological_process|,molecular_function|,10,0.4,0.602,10,0.2,0.471,0.2,0.822,0.822,0.546,0,0,-0.8,1.8
ENSMUSG00000051703,TMEM198,transmembrane protein 198,plasma membrane|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|cytoplasmic vesicle|,multicellular organismal development|Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,molecular_function|,10,0.2,1.05,10,0,0,0.1,0.821,0.821,0.546,0,0,-1.1,1.6
ENSMUSG00000012017,SCARF2,"scavenger receptor class F, member 2",cellular_component|membrane|integral component of membrane|,receptor-mediated endocytosis|cell adhesion|heterophilic cell-cell adhesion|,scavenger receptor activity|,10,0.1,0.0195,10,0.5,1.79,0.2,0.82,0.82,0.547,0,0,-0.9,1.8
ENSMUSG00000037913,TMEM156,transmembrane protein 156,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.364,10,-0.2,0.653,-0.2,0.82,-0.82,0.547,0,0,-1.7,1.1
ENSMUSG00000058831,OPN1SW,"opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)",photoreceptor outer segment|photoreceptor outer segment|membrane|integral component of membrane|terminal bouton|cell body|,signal transduction|G-protein coupled receptor signaling pathway|visual perception|phototransduction|protein-chromophore linkage|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|photoreceptor activity|,10,-0.3,0.48,10,2,4.35,2,0.812,0.812,0.549,0,0,-0.5,4
ENSMUSG00000030798,CD37,CD37 antigen,immunological synapse|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,positive regulation of immunoglobulin production|regulation of humoral immune response|negative regulation of cell proliferation|negative regulation of myeloid dendritic cell activation|defense response to protozoan|regulation of defense response to virus|,None,10,-0.3,1.56,10,0,0,-0.2,0.805,-0.805,0.551,0,0,-1.8,1
ENSMUSG00000031823,ZDHHC7,"zinc finger, DHHC domain containing 7",Golgi apparatus|membrane|integral component of membrane|,peptidyl-L-cysteine S-palmitoylation|protein palmitoylation|protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.3,1.49,10,-0.3,2.52,-0.2,0.802,-0.802,0.552,0,0,-1.7,1.1
ENSMUSG00000049047,ARMCX3,"armadillo repeat containing, X-linked 3",membrane|integral component of membrane|integral component of mitochondrial outer membrane|,cellular protein localization|positive regulation of transcription from RNA polymerase II promoter|,protein binding|,10,0.9,3.65,10,-0.8,2.34,0.9,0.799,0.799,0.552,0,0,-1.3,2
ENSMUSG00000040006,GINM1,glycoprotein integral membrane 1,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.2,1.09,10,-0.1,0.164,0.2,0.787,0.787,0.556,0,0,-1.8,1.1
ENSMUSG00000045205,DPY19L4,dpy-19-like 4 (C. elegans),cellular_component|membrane|integral component of membrane|,biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.2,0.89,10,0.1,0.147,0.2,0.785,0.785,0.556,0,0,-1,1.7
ENSMUSG00000032850,RNFT2,"ring finger protein, transmembrane 2",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0,0,10,-0.6,2.19,-0.2,0.779,-0.779,0.558,0,0,-1.8,0.8
ENSMUSG00000036553,SH3TC1,SH3 domain and tetratricopeptide repeats 1,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.56,10,0.1,0.0042,-0.3,0.778,-0.778,0.558,0,0,-1.7,0.9
ENSMUSG00000044134,FAM109A,"family with sequence similarity 109, member A",endosome|early endosome|Golgi apparatus|trans-Golgi network|clathrin-coated vesicle|cytoplasmic vesicle|recycling endosome|,"receptor recycling|endosome organization|retrograde transport, endosome to Golgi|",protein homodimerization activity|,10,0.6,0.389,10,0.2,0.506,0.3,0.776,0.776,0.559,0,0,-0.5,1.9
ENSMUSG00000022257,LAPTM4B,lysosomal-associated protein transmembrane 4B,membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0.1,0.0727,10,0.2,0.803,0.2,0.775,0.775,0.559,0,0,-0.8,1.8
ENSMUSG00000027900,DRAM2,DNA-damage regulated autophagy modulator 2,cytoplasm|lysosome|Golgi apparatus|microtubule cytoskeleton|membrane|integral component of membrane|intracellular membrane-bounded organelle|,apoptotic process|apoptotic nuclear changes|,molecular_function|,10,0,0,10,1.3,1.51,0.9,0.771,0.771,0.56,0,0,-0.5,2
ENSMUSG00000053094,TMEM248,transmembrane protein 248,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.2,0.71,9,0.6,1.94,0.4,0.771,0.771,0.56,0,0,-0.8,1.9
ENSMUSG00000035314,GDPD5,glycerophosphodiester phosphodiesterase domain containing 5,cytoplasm|membrane|integral component of membrane|cell projection|,glycerol metabolic process|lipid metabolic process|nervous system development|spinal cord motor neuron differentiation|cerebral cortex neuron differentiation|neuron projection development|positive regulation of neuron differentiation|negative regulation of Notch signaling pathway|negative regulation of Notch signaling pathway|regulation of timing of cell differentiation|,nuclease activity|phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,0.2,1.28,10,-0.3,1.44,0.2,0.765,0.765,0.562,0,0,-1.4,1.2
ENSMUSG00000030156,CD69,CD69 antigen,external side of plasma membrane|membrane|integral component of membrane|,None,calcium ion binding|carbohydrate binding|,10,-0.3,0.523,10,-0.4,0.447,-0.3,0.759,-0.759,0.564,0,0,-1.7,1.1
ENSMUSG00000028403,ZDHHC21,"zinc finger, DHHC domain containing 21",Golgi apparatus|plasma membrane|membrane|integral component of membrane|,hair follicle development|peptidyl-L-cysteine S-palmitoylation|protein palmitoylation|protein palmitoylation|sebaceous gland development|,"zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,-0.1,0.153,10,-0.2,0.724,-0.1,0.755,-0.755,0.565,0,0,-1.7,1
ENSMUSG00000025505,TMEM80,transmembrane protein 80,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.3,1.93,-0.3,0.752,-0.752,0.565,0,0,-1.8,0.9
ENSMUSG00000049551,FZD9,frizzled homolog 9 (Drosophila),cytoplasm|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|filopodium membrane|perinuclear region of cytoplasm|,vasculature development|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|multicellular organismal development|neuroblast proliferation|brain development|learning or memory|gonad development|embryo development|Wnt signaling pathway|B cell differentiation|canonical Wnt signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|Wnt-protein binding|Wnt-protein binding|PDZ domain binding|protein homodimerization activity|Wnt-activated receptor activity|Wnt-activated receptor activity|protein heterodimerization activity|,10,0.4,1.25,10,-0.4,1.3,-0.2,0.748,-0.748,0.566,0,0,-1.5,1.5
ENSMUSG00000020007,IL20RA,"interleukin 20 receptor, alpha",cellular_component|membrane|integral component of membrane|,cytokine-mediated signaling pathway|regulation of bone resorption|positive regulation of intrinsic apoptotic signaling pathway|,interleukin-20 binding|,10,0.3,0.676,10,0.2,0.146,0.2,0.734,0.734,0.571,0,0,-0.7,1.8
ENSMUSG00000028232,TMEM68,transmembrane protein 68,cellular_component|membrane|integral component of membrane|,biological_process|metabolic process|,"molecular_function|transferase activity, transferring acyl groups|",10,0.1,0.28,10,0.2,0.576,0.1,0.728,0.728,0.572,0,0,-1.8,1.4
ENSMUSG00000061666,GDPD1,glycerophosphodiester phosphodiesterase domain containing 1,membrane|membrane|integral component of membrane|,glycerol metabolic process|lipid metabolic process|biological_process|,molecular_function|nuclease activity|phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0.2,0.563,10,0.1,0.269,0.2,0.728,0.728,0.572,0,0,-1.3,1.4
ENSMUSG00000006143,UPK3BL,uroplakin 3B-like,cellular_component|membrane|integral component of membrane|,response to oxidative stress|biological_process|oxidation-reduction process|,molecular_function|peroxidase activity|heme binding|,10,-0.2,0.861,10,0,0,-0.2,0.727,-0.727,0.572,0,0,-1.5,1.2
ENSMUSG00000026271,GPR35,G protein-coupled receptor 35,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0.1,0.147,10,0.5,1.2,0.3,0.714,0.714,0.576,0,0,-0.9,1.7
ENSMUSG00000034452,SLC24A1,"solute carrier family 24 (sodium/potassium/calcium exchanger), member 1",membrane|integral component of membrane|intrinsic component of plasma membrane|,sodium ion transmembrane transport|calcium ion transmembrane transport|potassium ion transmembrane transport|,"calcium, potassium:sodium antiporter activity|",10,0.5,1.09,10,-0.2,1.03,-0.2,0.713,-0.713,0.576,0,0,-1.1,1.7
ENSMUSG00000035107,DCBLD2,"discoidin, CUB and LCCL domain containing 2",integral component of plasma membrane|cell surface|membrane|integral component of membrane|,cell adhesion|negative regulation of cell growth|wound healing|,None,10,0,0,10,-0.2,1.43,-0.1,0.71,-0.71,0.577,0,0,-1.6,1.2
ENSMUSG00000046822,SLC39A3,"solute carrier family 39 (zinc transporter), member 3",membrane|integral component of membrane|,transport|ion transport|zinc ion transport|metal ion transport|transmembrane transport|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|metal ion transmembrane transporter activity|,10,0,0,10,-0.2,1.28,-0.2,0.709,-0.709,0.577,0,0,-1.7,1.1
ENSMUSG00000075593,GAL3ST4,galactose-3-O-sulfotransferase 4,membrane|extracellular vesicular exosome|,glycoprotein biosynthetic process|,galactose 3-O-sulfotransferase activity|,10,0,0,10,-0.4,1.9,-0.3,0.708,-0.708,0.578,0,0,-1.3,1.6
ENSMUSG00000064115,CADM2,cell adhesion molecule 2,cytoplasm|plasma membrane|membrane|integral component of membrane|cell junction|axon|neuronal cell body membrane|cell projection|synapse|,cell adhesion|,protein binding|,10,0.2,0.42,10,-0.5,1.63,-0.4,0.706,-0.706,0.578,0,0,-1.8,0.9
ENSMUSG00000041460,CACNA2D4,"calcium channel, voltage-dependent, alpha 2/delta subunit 4",voltage-gated calcium channel complex|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|detection of light stimulus involved in visual perception|calcium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|metal ion binding|,10,-0.1,0.046,10,-0.2,0.94,-0.2,0.703,-0.703,0.579,0,0,-1.8,0.9
ENSMUSG00000025511,TSPAN4,tetraspanin 4,plasma membrane|membrane|integral component of membrane|vesicle|,protein complex assembly|,antigen binding|integrin binding|protein binding|,10,0.2,1.13,10,-0.2,0.72,0.2,0.703,0.703,0.579,0,0,-1.6,1.4
ENSMUSG00000022537,TMEM44,transmembrane protein 44,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.807,10,0.4,1.26,-0.2,0.702,-0.702,0.579,0,0,-1.4,1.5
ENSMUSG00000002032,TMEM25,transmembrane protein 25,cellular_component|extracellular region|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,0.752,10,0.4,3.05,0.4,0.699,0.699,0.58,0,0,-1.4,1.4
ENSMUSG00000027775,MFSD1,major facilitator superfamily domain containing 1,cellular_component|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,0,0,10,-0.3,1.47,-0.2,0.694,-0.694,0.582,0,0,-1.8,0.8
ENSMUSG00000032324,TSPAN3,tetraspanin 3,membrane|integral component of membrane|extracellular vesicular exosome|,None,None,10,0,0,10,0.4,1.87,0.2,0.693,0.693,0.582,0,0,-0.8,1.8
ENSMUSG00000059791,NRM,nurim (nuclear envelope membrane protein),nucleus|nuclear envelope|nuclear inner membrane|nuclear lamina|membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-1,1.15,10,-0.1,0.52,-0.1,0.689,-0.689,0.583,0,0,-2,0.7
ENSMUSG00000024180,TMEM8,transmembrane protein 8 (five membrane-spanning domains),lysosomal membrane|integral component of plasma membrane|membrane|integral component of membrane|,cell adhesion|biological_process|,molecular_function|,10,0,0,10,0.2,1.15,0.2,0.683,0.683,0.585,0,0,-0.9,1.8
ENSMUSG00000025389,MIP,major intrinsic protein of eye lens fiber,plasma membrane|gap junction|membrane|integral component of membrane|cell junction|intracellular membrane-bounded organelle|intracellular canaliculus|,lens development in camera-type eye|transport|water transport|water transport|cell communication|visual perception|canalicular bile acid transport|response to stimulus|transmembrane transport|,structural constituent of eye lens|transporter activity|protein binding|water channel activity|water channel activity|channel activity|,10,0,0,10,-0.2,0.973,-0.2,0.675,-0.675,0.587,0,0,-2,0.9
ENSMUSG00000044033,CCDC141,coiled-coil domain containing 141,cytoplasm|centrosome|,cerebral cortex radially oriented cell migration|centrosome localization|,protein binding|,10,-0.1,0.29,10,-0.3,0.57,-0.2,0.671,-0.671,0.588,0,0,-1.5,1.2
ENSMUSG00000064158,IZUMO1,izumo sperm-egg fusion 1,acrosomal vesicle|acrosomal membrane|membrane|integral component of membrane|integral component of membrane|,cell adhesion|single fertilization|fusion of sperm to egg plasma membrane|fusion of sperm to egg plasma membrane|fusion of sperm to egg plasma membrane|sperm-egg recognition|,receptor binding|receptor binding|protein binding|protein homodimerization activity|protein homodimerization activity|,10,-0.1,0.093,10,-0.3,1.22,-0.2,0.663,-0.663,0.591,0,0,-1.5,1.5
ENSMUSG00000024036,SLC37A1,"solute carrier family 37 (glycerol-3-phosphate transporter), member 1",membrane|,biological_process|,molecular_function|,10,0.1,0.142,10,0.2,0.767,0.1,0.662,0.662,0.591,0,0,-1.2,1.6
ENSMUSG00000023473,CELSR3,"cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)",plasma membrane|membrane|integral component of membrane|,neuron migration|cell adhesion|homophilic cell adhesion|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|multicellular organismal development|axonal fasciculation|regulation of protein localization|cilium assembly|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcium ion binding|,10,-0.2,1.22,10,0,0,-0.2,0.662,-0.662,0.591,0,0,-1.7,1
ENSMUSG00000050549,5730508B09RIK,RIKEN cDNA 5730508B09 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-1.5,3.84,-1.5,0.658,-0.658,0.592,0,0,-3,0.3
ENSMUSG00000028803,NIPAL3,NIPA-like domain containing 3,membrane|integral component of membrane|,magnesium ion transport|,magnesium ion transmembrane transporter activity|,10,-0.3,0.832,10,0.6,2.4,-0.2,0.657,-0.657,0.593,0,0,-1.1,1.6
ENSMUSG00000028797,TMEM234,transmembrane protein 234,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-1.2,2.6,0.2,0.655,0.655,0.593,0,0,-2,0.9
ENSMUSG00000067714,LPAR5,lysophosphatidic acid receptor 5,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.3,1.4,10,0,0,-0.1,0.652,-0.652,0.594,0,0,-1.7,1
ENSMUSG00000037221,MOSPD3,motile sperm domain containing 3,membrane|integral component of membrane|,heart development|,structural molecule activity|protein binding|,10,0.1,0.32,10,0.1,0.381,0.1,0.642,0.642,0.597,0,0,-1.2,1.6
ENSMUSG00000022440,C1QTNF6,C1q and tumor necrosis factor related protein 6,extracellular region|collagen trimer|extracellular space|,protein oligomerization|protein heterotrimerization|,identical protein binding|,10,0.8,0.896,10,0.1,0.251,0.1,0.636,0.636,0.599,0,0,-1.3,1.8
ENSMUSG00000042428,MGAT3,mannoside acetylglucosaminyltransferase 3,None,None,transferase activity|,9,-0.1,0.0546,9,-0.2,0.665,-0.2,0.634,-0.634,0.6,0,0,-1.1,2
ENSMUSG00000059448,OLFR156,olfactory receptor 156,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.101,10,-0.6,1.31,-0.1,0.629,-0.629,0.601,0,0,-1.9,0.9
ENSMUSG00000032741,TPCN1,two pore channel 1,lysosome|lysosomal membrane|endosome|plasma membrane|endosome membrane|membrane|integral component of membrane|,transport|ion transport|calcium ion transport|ion transmembrane transport|regulation of ion transmembrane transport|transmembrane transport|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|identical protein binding|NAADP-sensitive calcium-release channel activity|NAADP-sensitive calcium-release channel activity|,10,-0.2,0.933,10,0.1,0.036,-0.1,0.627,-0.627,0.602,0,0,-1.5,1.3
ENSMUSG00000000154,SLC22A18,"solute carrier family 22 (organic cation transporter), member 18",nuclear envelope|cytoplasm|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|apical plasma membrane|,transport|ion transport|anion transport|drug transmembrane transport|organic anion transport|drug transport|ion transmembrane transport|transmembrane transport|,transporter activity|organic anion transmembrane transporter activity|drug transmembrane transporter activity|symporter activity|ubiquitin protein ligase binding|,10,0.1,0.242,10,-0.3,2.34,-0.3,0.618,-0.618,0.605,0,0,-1.5,1.5
ENSMUSG00000039199,ZDHHC1,"zinc finger, DHHC domain containing 1",endoplasmic reticulum|membrane|integral component of membrane|extracellular vesicular exosome|,protein palmitoylation|protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0.5,0.35,10,0.3,0.503,0.5,0.616,0.616,0.605,0,0,-1.3,1.6
ENSMUSG00000027340,SLC23A2,"solute carrier family 23 (nucleobase transporters), member 2",cytoplasm|cytoplasm|plasma membrane|integral component of plasma membrane|basal plasma membrane|basal plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|,transport|ion transport|sodium ion transport|L-ascorbic acid transport|L-ascorbic acid transport|L-ascorbic acid transport|L-ascorbic acid transport|L-ascorbic acid metabolic process|carbohydrate transmembrane transport|vitamin transmembrane transport|vitamin transmembrane transport|sodium ion transmembrane transport|transmembrane transport|transepithelial L-ascorbic acid transport|,transporter activity|L-ascorbate:sodium symporter activity|L-ascorbate:sodium symporter activity|L-ascorbate:sodium symporter activity|L-ascorbic acid transporter activity|L-ascorbic acid transporter activity|L-ascorbic acid transporter activity|symporter activity|sodium-dependent L-ascorbate transmembrane transporter activity|,10,-0.3,1.62,10,0.5,2.92,0.4,0.611,0.611,0.607,0,0,-1.3,1.6
ENSMUSG00000028262,CLCA2,chloride channel calcium activated 2,integral component of plasma membrane|,chloride transport|anoikis|extrinsic apoptotic signaling pathway in absence of ligand|chloride transmembrane transport|,intracellular calcium activated chloride channel activity|,10,-0.1,0.404,10,-0.2,0.31,-0.2,0.608,-0.608,0.608,0,0,-1.5,1.3
ENSMUSG00000055003,LRTM2,leucine-rich repeats and transmembrane domains 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,1.68,10,-0.3,0.719,0.3,0.603,0.603,0.609,0,0,-1.2,1.5
ENSMUSG00000057411,FAM173A,"family with sequence similarity 173, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.07,10,0.4,1.87,0.2,0.597,0.597,0.611,0,0,-1.2,1.4
ENSMUSG00000047554,TMEM41B,transmembrane protein 41B,cellular_component|membrane|integral component of membrane|,nervous system development|biological_process|,molecular_function|,9,0.5,1.67,9,0.1,0.103,0.2,0.595,0.595,0.612,0,0,-1.1,1.8
ENSMUSG00000052819,BEST2,bestrophin 2,plasma membrane|cilium|membrane|integral component of membrane|chloride channel complex|,transport|ion transport|chloride transport|membrane depolarization|chloride transmembrane transport|,chloride channel activity|chloride channel activity|,10,0,0,10,0.4,2.24,0.2,0.593,0.593,0.612,0,0,-0.8,1.8
ENSMUSG00000030577,CD22,CD22 antigen,plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|cell surface receptor signaling pathway|,protein binding|coreceptor activity|,10,-0.5,0.6,10,0.2,0.269,-0.4,0.593,-0.593,0.612,0,0,-1.7,1.1
ENSMUSG00000028039,EFNA3,ephrin A3,plasma membrane|membrane|anchored component of membrane|,axon guidance|regulation of neuron differentiation|ephrin receptor signaling pathway|,ephrin receptor binding|ephrin receptor binding|,9,-0.7,0.453,9,0.3,0.695,0.2,0.589,0.589,0.614,0,0,-1.9,1.1
ENSMUSG00000048988,ELFN1,"leucine rich repeat and fibronectin type III, extracellular 1",membrane|integral component of membrane|dendrite|cell projection|excitatory synapse|extracellular vesicular exosome|,negative regulation of phosphatase activity|synapse organization|,protein phosphatase inhibitor activity|phosphatase binding|,10,0.2,0.862,10,0.1,0.0468,0.1,0.588,0.588,0.614,0,0,-0.8,1.9
ENSMUSG00000044216,KCNJ4,"potassium inwardly-rectifying channel, subfamily J, member 4",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|cell junction|dendrite|cytoplasmic vesicle|neuronal cell body|synapse|postsynaptic membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|PDZ domain binding|,10,0.2,0.232,10,0.4,0.476,0.2,0.588,0.588,0.614,0,0,-0.8,1.9
ENSMUSG00000038552,FNDC4,fibronectin type III domain containing 4,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.397,10,-0.1,0.24,-0.1,0.581,-0.581,0.616,0,0,-1.6,1.2
ENSMUSG00000030352,TSPAN9,tetraspanin 9,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.628,10,-0.3,1.18,-0.3,0.58,-0.58,0.616,0,0,-1.5,1.3
ENSMUSG00000026576,ATP1B1,"ATPase, Na+/K+ transporting, beta 1 polypeptide",plasma membrane|sodium:potassium-exchanging ATPase complex|caveola|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|extracellular vesicular exosome|,response to hypoxia|blastocyst development|ATP catabolic process|transport|ion transport|potassium ion transport|sodium ion transport|cell adhesion|metal ion transport|sodium ion transmembrane transport|potassium ion transmembrane transport|,sodium:potassium-exchanging ATPase activity|protein binding|MHC class II protein complex binding|,10,0.2,1.12,10,-0.1,0.085,0.2,0.576,0.576,0.618,0,0,-1.4,1.4
ENSMUSG00000047216,CDH19,"cadherin 19, type 2",cellular_component|plasma membrane|membrane|integral component of membrane|,cell adhesion|biological_process|,molecular_function|,10,0,0,9,0.4,1.14,0.1,0.567,0.567,0.621,0,0,-0.7,2
ENSMUSG00000041377,NINJ2,ninjurin 2,membrane|integral component of membrane|,cell adhesion|tissue regeneration|,None,10,0.7,1.21,10,0.3,0.578,0.3,0.565,0.565,0.621,0,0,-1,1.9
ENSMUSG00000054662,ANO9,anoctamin 9,intracellular|plasma membrane|membrane|integral component of membrane|,chloride transport|phospholipid transport|calcium activated phosphatidylserine scrambling|calcium activated phosphatidylcholine scrambling|calcium activated galactosylceramide scrambling|chloride transmembrane transport|negative regulation of intracellular calcium activated chloride channel activity|,phospholipid scramblase activity|,10,0.5,1.02,10,0.1,0.187,0.4,0.565,0.565,0.621,0,0,-0.8,1.8
ENSMUSG00000037455,SLC18B1,"solute carrier family 18, subfamily B, member 1",cellular_component|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|,10,-0.2,0.424,10,-0.1,0.202,-0.1,0.56,-0.56,0.623,0,0,-1.6,1.2
ENSMUSG00000056966,GJC3,"gap junction protein, gamma 3",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|myelin sheath|,cell communication|cell-cell signaling|sensory perception of sound|myelination|transmembrane transport|,gap junction channel activity|protein homodimerization activity|,10,-0.2,0.192,10,-0.2,0.417,-0.2,0.557,-0.557,0.624,0,0,-1.3,1.7
ENSMUSG00000036327,QSOX2,quiescin Q6 sulfhydryl oxidase 2,cellular_component|membrane|integral component of membrane|,cell redox homeostasis|oxidation-reduction process|,oxidoreductase activity|thiol oxidase activity|,10,-0.2,0.345,10,-0.4,0.376,-0.2,0.557,-0.557,0.624,0,0,-1.7,1
ENSMUSG00000033589,REEP4,receptor accessory protein 4,endoplasmic reticulum|microtubule|membrane|integral component of membrane|,nuclear envelope organization|cell cycle|mitotic nuclear division|mitotic nuclear envelope reassembly|cell division|,molecular_function|,10,-0.2,0.992,10,0.2,0.599,0.1,0.557,0.557,0.624,0,0,-1.3,1.5
ENSMUSG00000040612,ILDR2,immunoglobulin-like domain containing receptor 2,cell|endoplasmic reticulum|membrane|integral component of membrane|,response to glucose|insulin secretion|cell differentiation|pancreas development|homeostasis of number of cells within a tissue|,None,10,-0.1,0.0282,10,-0.1,0.574,-0.1,0.554,-0.554,0.625,0,0,-1.6,1.2
ENSMUSG00000020023,TMCC3,transmembrane and coiled coil domains 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.116,10,0.5,1.93,-0.2,0.552,-0.552,0.626,0,0,-1.2,1.6
ENSMUSG00000032816,IGDCC4,"immunoglobulin superfamily, DCC subclass, member 4",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.305,10,0.4,0.61,0.3,0.538,0.538,0.63,0,0,-1,1.7
ENSMUSG00000017692,RHBDL3,"rhomboid, veinlet-like 3 (Drosophila)",membrane|integral component of membrane|,proteolysis|biological_process|,serine-type endopeptidase activity|calcium ion binding|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.771,10,0,0,0.1,0.538,0.538,0.63,0,0,-1.2,1.6
ENSMUSG00000038498,CATSPER1,"cation channel, sperm associated 1",plasma membrane|cilium|membrane|integral component of membrane|CatSper complex|cell projection|,transport|ion transport|calcium ion transport|multicellular organismal development|spermatogenesis|fusion of sperm to egg plasma membrane|cell differentiation|sperm motility|regulation of ion transmembrane transport|regulation of calcium ion transport|transmembrane transport|regulation of cilium beat frequency involved in ciliary motility|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|calcium activated cation channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|,10,0.5,0.756,10,-0.1,0.0196,-0.1,0.537,-0.537,0.63,0,0,-1.5,1.5
ENSMUSG00000028950,TAS1R1,"taste receptor, type 1, member 1",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|detection of chemical stimulus involved in sensory perception of taste|sensory perception of umami taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|,10,1.1,3.06,10,0,0,0.2,0.535,0.535,0.631,0,0,-0.8,2
ENSMUSG00000032806,SLC10A3,"solute carrier family 10 (sodium/bile acid cotransporter family), member 3",membrane|integral component of membrane|,transport|sodium ion transport|response to organic substance|response to retinoic acid|,bile acid:sodium symporter activity|symporter activity|,10,0.1,0.463,10,-0.2,0.858,0.1,0.535,0.535,0.631,0,0,-1.3,1.5
ENSMUSG00000038079,TMEM237,transmembrane protein 237,cilium|membrane|membrane|integral component of membrane|ciliary transition zone|ciliary transition zone|cell projection|,cell projection organization|regulation of Wnt signaling pathway|regulation of Wnt signaling pathway|cilium assembly|cilium assembly|,molecular_function|,10,0,0,10,0.6,1.17,0.6,0.533,0.533,0.632,0,0,-0.5,2
ENSMUSG00000062785,KCNC3,"potassium voltage gated channel, Shaw-related subfamily, member 3",voltage-gated potassium channel complex|membrane|integral component of membrane|axolemma|neuromuscular junction|dendrite membrane|neuronal cell body membrane|axon terminus|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|regulation of neurotransmitter secretion|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0,0,10,0.2,1.22,0.2,0.532,0.532,0.632,0,0,-0.9,1.8
ENSMUSG00000044156,HEPACAM2,HEPACAM family member 2,cytoplasm|Golgi apparatus|centrosome|spindle|cytoskeleton|membrane|integral component of membrane|midbody|,cell cycle|mitotic nuclear division|centrosome organization|cell division|,molecular_function|,10,0.3,1.32,10,-0.1,0.127,0.2,0.532,0.532,0.632,0,0,-1.1,1.6
ENSMUSG00000061626,OLFR68,olfactory receptor 68,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.00946,10,-0.3,1.78,-0.2,0.532,-0.532,0.632,0,0,-1.6,1.1
ENSMUSG00000056856,JAKMIP3,janus kinase and microtubule interacting protein 3,cellular_component|Golgi apparatus|,biological_process|,molecular_function|microtubule binding|kinase binding|,10,0.3,0.741,10,-0.1,0.109,0.2,0.53,0.53,0.633,0,0,-1,1.7
ENSMUSG00000060227,CASC4,cancer susceptibility candidate 4,Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.4,2.36,-0.3,0.527,-0.527,0.634,0,0,-1.8,0.8
ENSMUSG00000027860,VANGL1,"vang-like 1 (van gogh, Drosophila)",plasma membrane|membrane|integral component of membrane|lateral plasma membrane|,multicellular organismal development|,protein binding|,10,-0.2,0.231,10,-0.2,0.343,-0.2,0.525,-0.525,0.635,0,0,-1.7,1
ENSMUSG00000022762,NCAM2,neural cell adhesion molecule 2,plasma membrane|membrane|integral component of membrane|axon|anchored component of membrane|,cell adhesion|,None,10,0,0,10,0.3,1.05,0.2,0.519,0.519,0.637,0,0,-1.1,1.7
ENSMUSG00000041644,SLC5A12,"solute carrier family 5 (sodium/glucose cotransporter), member 12",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|transmembrane transport|,transporter activity|symporter activity|,10,-0.4,0.855,10,0.2,0.35,0.2,0.516,0.516,0.638,0,0,-1.6,1.3
ENSMUSG00000014353,TMEM87B,transmembrane protein 87B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0731,10,0.2,0.64,0.2,0.513,0.513,0.639,0,0,-1.5,1.3
ENSMUSG00000025163,CD7,CD7 antigen,membrane|integral component of membrane|extracellular vesicular exosome|,immune system process|homeostasis of number of cells within a tissue|,None,10,-0.1,0.196,10,-0.1,0.364,-0.1,0.512,-0.512,0.639,0,0,-1.9,0.8
ENSMUSG00000001946,ESAM,endothelial cell-specific adhesion molecule,plasma membrane|adherens junction|tight junction|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|single organismal cell-cell adhesion|calcium-independent cell-cell adhesion|,None,9,0.2,0.847,9,0,0,0.2,0.504,0.504,0.642,0,0,-1.1,1.7
ENSMUSG00000028051,HCN3,"hyperpolarization-activated, cyclic nucleotide-gated K+ 3",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|sodium ion transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,nucleotide binding|ion channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|potassium channel activity|sodium channel activity|protein binding|cAMP binding|,10,-0.1,0.0635,10,-0.1,0.485,-0.1,0.503,-0.503,0.643,0,0,-1.6,1.3
ENSMUSG00000042246,TMC7,transmembrane channel-like gene family 7,cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.2,0.578,10,0.1,0.139,0.1,0.503,0.503,0.643,0,0,-1.6,1.5
ENSMUSG00000026068,IL18RAP,interleukin 18 receptor accessory protein,membrane|integral component of membrane|,signal transduction|,interleukin-1 receptor activity|,10,-0.5,2.2,10,0.3,0.832,0.1,0.493,0.493,0.646,0,0,-1.6,1.5
ENSMUSG00000031111,IGSF1,"immunoglobulin superfamily, member 1",extracellular region|membrane|integral component of membrane|,"regulation of transcription, DNA-templated|signal transduction|",receptor activity|coreceptor activity|inhibin binding|,9,0.2,0.66,9,-0.1,0.0252,0.2,0.491,0.491,0.647,0,0,-1.2,1.6
ENSMUSG00000043671,DPY19L3,dpy-19-like 3 (C. elegans),cellular_component|membrane|integral component of membrane|,biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.2,0.499,10,0.1,0.0448,0.2,0.49,0.49,0.647,0,0,-0.9,1.8
ENSMUSG00000023032,SLC4A8,"solute carrier family 4 (anion exchanger), member 8",plasma membrane|membrane|integral component of membrane|neuronal cell body membrane|neuron projection|,transport|ion transport|sodium ion transport|anion transport|embryo development|,transporter activity|inorganic anion exchanger activity|anion transmembrane transporter activity|antiporter activity|anion:anion antiporter activity|,10,-0.5,0.749,10,0.4,1.11,-0.1,0.489,-0.489,0.648,0,0,-1.2,1.8
ENSMUSG00000049488,TMEM67,transmembrane protein 67,cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|centrosome|cytoskeleton|plasma membrane|cilium|membrane|integral component of membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle membrane|TCTN-B9D complex|cell projection|ciliary membrane|,negative regulation of centrosome duplication|negative regulation of centrosome duplication|cell projection organization|ER-associated ubiquitin-dependent protein catabolic process|cilium assembly|cilium assembly|branching morphogenesis of an epithelial tube|cilium morphogenesis|,filamin binding|unfolded protein binding|,10,-0.2,0.634,10,-0.1,0.11,-0.2,0.489,-0.489,0.648,0,0,-1.8,0.9
ENSMUSG00000092586,LY6G6C,"lymphocyte antigen 6 complex, locus G6C",cellular_component|plasma membrane|membrane|anchored component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.3,1.11,0.2,0.487,0.487,0.648,0,0,-0.9,1.7
ENSMUSG00000044052,CCR10,chemokine (C-C motif) receptor 10,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,chemotaxis|immune response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|,10,0.2,1.26,10,0,0,0.2,0.484,0.484,0.649,0,0,-1,1.7
ENSMUSG00000040123,ZMYM5,"zinc finger, MYM-type 5",cellular_component|nucleus|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.2,0.302,10,-0.1,0.285,-0.1,0.483,-0.483,0.65,0,0,-1.6,1.1
ENSMUSG00000029189,SEL1L3,sel-1 suppressor of lin-12-like 3 (C. elegans),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.264,10,0.2,0.279,0.1,0.477,0.477,0.652,0,0,-1.2,1.6
ENSMUSG00000061577,GPR114,G protein-coupled receptor 114,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0,0,10,-0.3,1.26,-0.2,0.475,-0.475,0.653,0,0,-1.7,1
ENSMUSG00000039463,SLC9A8,"solute carrier family 9 (sodium/hydrogen exchanger), member 8",Golgi apparatus|membrane|integral component of membrane|,transport|ion transport|cation transport|potassium ion transport|sodium ion transport|regulation of pH|sodium ion transmembrane transport|regulation of intracellular pH|transmembrane transport|potassium ion transmembrane transport|hydrogen ion transmembrane transport|,antiporter activity|solute:proton antiporter activity|sodium:proton antiporter activity|potassium:proton antiporter activity|,10,0.1,0.145,10,0.8,1.78,0.1,0.474,0.474,0.653,0,0,-0.6,2
ENSMUSG00000045463,SLCO6B1,"solute carrier organic anion transporter family, member 6b1",integral component of plasma membrane|,organic anion transport|ion transmembrane transport|,organic anion transmembrane transporter activity|,10,0.2,0.131,10,0.2,0.386,0.2,0.473,0.473,0.653,0,0,-0.9,1.8
ENSMUSG00000078584,AU022252,expressed sequence AU022252,cellular_component|,biological_process|,molecular_function|,10,0.5,1.26,10,0.1,0.0381,0.2,0.473,0.473,0.653,0,0,-1.2,1.7
ENSMUSG00000053391,OLFR211,olfactory receptor 211,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.2,0.953,0.1,0.466,0.466,0.656,0,0,-1.4,1.4
ENSMUSG00000030292,SMCO2,single-pass membrane protein with coiled-coil domains 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.983,-0.2,0.459,-0.459,0.659,0,0,-1.9,0.8
ENSMUSG00000016028,CELSR1,"cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)",intracellular|nucleus|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,gastrulation with mouth forming second|establishment of planar polarity|neuron migration|neural tube closure|neural tube closure|hair follicle development|cell adhesion|homophilic cell adhesion|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|Rho protein signal transduction|cell-cell signaling|multicellular organismal development|central nervous system development|locomotory behavior|anterior/posterior pattern specification|regulation of actin cytoskeleton organization|wound healing|establishment of planar polarity of embryonic epithelium|inner ear morphogenesis|apical protein localization|regulation of neurotransmitter secretion|establishment of body hair planar orientation|orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis|planar dichotomous subdivision of terminal units involved in lung branching morphogenesis|lateral sprouting involved in lung morphogenesis|planar cell polarity pathway involved in neural tube closure|protein localization involved in establishment of planar polarity|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcium ion binding|protein binding|protein dimerization activity|,10,0.2,1.37,10,-0.1,0.0273,0.1,0.457,0.457,0.659,0,0,-1.2,1.6
ENSMUSG00000003665,HAS1,hyaluronan synthase1,membrane|integral component of membrane|,negative regulation of fibroblast migration|hyaluronan biosynthetic process|hyaluronan biosynthetic process|cellular response to platelet-derived growth factor stimulus|extracellular polysaccharide biosynthetic process|extracellular matrix assembly|,"transferase activity|transferase activity, transferring glycosyl groups|hyaluronan synthase activity|hyaluronan synthase activity|",10,-0.1,0.305,10,0.1,0.449,0.1,0.45,0.45,0.662,0,0,-1.1,1.7
ENSMUSG00000032913,LRIG2,leucine-rich repeats and immunoglobulin-like domains 2,cellular_component|cytoplasm|plasma membrane|membrane|integral component of membrane|,sensory perception of sound|regulation of platelet-derived growth factor receptor signaling pathway|innervation|,molecular_function|,10,0.5,1.92,10,0,0,0.3,0.437,0.437,0.667,0,0,-0.7,1.9
ENSMUSG00000044026,SLC35G1,"solute carrier family 35, member G1",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,0.458,10,0.2,0.293,-0.1,0.436,-0.436,0.667,0,0,-1.5,1.4
ENSMUSG00000014158,TRPV4,"transient receptor potential cation channel, subfamily V, member 4",cell|cytoplasmic microtubule|plasma membrane|plasma membrane|adherens junction|focal adhesion|cilium|cell surface|membrane|integral component of membrane|lamellipodium|cell junction|filopodium|growth cone|cortical actin cytoskeleton|cytoplasmic vesicle|ruffle membrane|,transport|ion transport|calcium ion transport|cellular calcium ion homeostasis|cellular calcium ion homeostasis|response to osmotic stress|response to osmotic stress|hypotonic response|actin filament organization|cell-cell junction assembly|positive regulation of cytosolic calcium ion concentration|osmosensory signaling pathway|osmosensory signaling pathway|negative regulation of neuron projection development|vasopressin secretion|positive regulation of microtubule depolymerization|actin cytoskeleton reorganization|cellular response to heat|hyperosmotic salinity response|cortical microtubule organization|microtubule polymerization|regulation of response to osmotic stress|transmembrane transport|calcium ion import|calcium ion import|calcium ion transmembrane transport|cellular response to osmotic stress|cellular hypotonic response|,nucleotide binding|actin binding|osmosensor activity|osmosensor activity|protein kinase C binding|ion channel activity|cation channel activity|calcium channel activity|calcium channel activity|calcium channel activity|protein binding|calmodulin binding|ATP binding|microtubule binding|protein kinase binding|protein kinase binding|SH2 domain binding|alpha-tubulin binding|beta-tubulin binding|actin filament binding|,10,0,0,10,0.8,1.68,0.1,0.433,0.433,0.668,0,0,-0.7,1.9
ENSMUSG00000054594,OSCAR,osteoclast associated receptor,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,None,None,10,0.1,0.408,10,-0.2,1.45,-0.2,0.428,-0.428,0.67,0,0,-1.6,1.1
ENSMUSG00000024018,CCDC167,coiled-coil domain containing 167,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.2,0.402,10,0.1,0.0711,0.1,0.427,0.427,0.671,0,0,-1.3,1.6
ENSMUSG00000034686,PRR7,proline rich 7 (synaptic),cellular_component|plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,biological_process|,molecular_function|,10,0,0,10,-1.3,3.12,-1.2,0.425,-0.425,0.672,0,0,-2,0.4
ENSMUSG00000001138,CNNM3,cyclin M3,plasma membrane|membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|adenyl nucleotide binding|,10,0.6,0.748,10,-0.5,0.535,0.2,0.419,0.419,0.674,0,0,-1.1,1.7
ENSMUSG00000056069,FAM105A,"family with sequence similarity 105, member A",cellular_component|,biological_process|,molecular_function|,10,0.1,0.0796,10,0.2,0.625,0.2,0.418,0.418,0.674,0,0,-1.2,1.6
ENSMUSG00000022744,CLDN25,claudin 25,membrane|integral component of membrane|apical plasma membrane|,biological_process|,molecular_function|,10,-0.2,1.23,10,0.7,0.606,-0.2,0.415,-0.415,0.675,0,0,-1.2,1.7
ENSMUSG00000071342,LSMEM1,leucine-rich single-pass membrane protein 1,cytoplasm|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.39,10,0.3,0.741,-0.2,0.413,-0.413,0.676,0,0,-1.4,1.4
ENSMUSG00000026811,ST6GALNAC6,"ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6",cytoplasm|Golgi apparatus|membrane|integral component of membrane|,ganglioside biosynthetic process|protein glycosylation|glycosylceramide metabolic process|glycosphingolipid metabolic process|glycoprotein metabolic process|oligosaccharide biosynthetic process|cell-cell recognition|sialylation|sialylation|,"alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity|sialyltransferase activity|sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",9,-0.2,1.07,9,0,0,-0.1,0.405,-0.405,0.679,0,0,-1.9,1
ENSMUSG00000027603,GGT7,gamma-glutamyltransferase 7,cellular_component|membrane|integral component of membrane|,glutathione metabolic process|glutathione biosynthetic process|biological_process|,"molecular_function|gamma-glutamyltransferase activity|transferase activity|transferase activity, transferring acyl groups|hydrolase activity|glutathione hydrolase activity|",10,0.2,0.59,10,0.1,0.0433,0.1,0.403,0.403,0.68,0,0,-1,1.7
ENSMUSG00000042804,GPR153,G protein-coupled receptor 153,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.4,2.08,10,0,0,-0.2,0.4,-0.4,0.681,0,0,-1.8,0.9
ENSMUSG00000048120,ENTPD1,ectonucleoside triphosphate diphosphohydrolase 1,basal lamina|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,ATP catabolic process|G-protein coupled receptor signaling pathway|purine ribonucleoside diphosphate catabolic process|platelet activation|,nucleotide binding|ATP binding|hydrolase activity|nucleoside-diphosphatase activity|nucleoside-triphosphatase activity|,10,-0.2,0.883,10,0.2,0.467,0.1,0.396,0.396,0.683,0,0,-1.2,1.7
ENSMUSG00000033770,CLCNKA,chloride channel Ka,endoplasmic reticulum|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|chloride channel complex|,transport|ion transport|chloride transport|regulation of ion transmembrane transport|regulation of body fluid levels|transmembrane transport|renal inner medulla development|chloride transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|protein binding|adenyl nucleotide binding|metal ion binding|,10,0.1,0.155,10,0.5,1.07,0.2,0.383,0.383,0.688,0,0,-0.7,2
ENSMUSG00000060538,TMEM219,transmembrane protein 219,cellular_component|plasma membrane|membrane|integral component of membrane|,apoptotic process|biological_process|,molecular_function|,10,0,0,10,0.3,1.14,0.1,0.379,0.379,0.69,0,0,-1.2,1.6
ENSMUSG00000044244,IL20RB,interleukin 20 receptor beta,None,negative regulation of type IV hypersensitivity|inflammatory response to antigenic stimulus|immune response-inhibiting signal transduction|negative regulation of interferon-gamma production|negative regulation of interleukin-2 production|positive regulation of interleukin-10 production|positive regulation of interleukin-4 production|negative regulation of T cell proliferation|homeostasis of number of cells within a tissue|regulation of T cell activation|,interleukin-20 binding|,10,0,0,9,0.3,1.14,0.1,0.374,0.374,0.692,0,0,-1.6,1.2
ENSMUSG00000009207,LNP,limb and neural patterns,endoplasmic reticulum membrane|membrane|integral component of membrane|,multicellular organismal development|blood coagulation|regulation of chondrocyte differentiation|embryonic forelimb morphogenesis|embryonic digit morphogenesis|,molecular_function|,9,0,0,10,0.4,1.52,0.1,0.373,0.373,0.692,0,0,-0.7,1.9
ENSMUSG00000001248,GRAMD1A,GRAM domain containing 1A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.517,10,0.1,0.0697,0.1,0.372,0.372,0.692,0,0,-1,1.7
ENSMUSG00000022848,DIRC2,disrupted in renal carcinoma 2 (human),cellular_component|lysosome|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,-0.1,0.175,10,0.8,1.84,-0.1,0.371,-0.371,0.693,0,0,-1.7,1.5
ENSMUSG00000042380,SMIM12,small integral membrane protein 12,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.71,10,1.1,0.046,0.3,0.369,0.369,0.693,0,0,-1.1,1.9
ENSMUSG00000040195,TMEM194,transmembrane protein 194,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.111,10,-0.1,0.29,-0.1,0.366,-0.366,0.695,0,0,-1.5,1.4
ENSMUSG00000027217,TSPAN18,tetraspanin 18,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.00447,10,-0.4,1.74,-0.2,0.357,-0.357,0.698,0,0,-1.5,1.2
ENSMUSG00000038217,TLCD2,TLC domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.547,10,-0.3,0.321,0.1,0.356,0.356,0.699,0,0,-1.3,1.4
ENSMUSG00000027887,SYPL2,synaptophysin-like 2,synaptic vesicle|membrane|integral component of membrane|integral component of synaptic vesicle membrane|,transport|cellular calcium ion homeostasis|,transporter activity|,10,0.8,1.44,10,0,0,0.1,0.356,0.356,0.699,0,0,-0.8,2
ENSMUSG00000034714,TTYH2,tweety homolog 2 (Drosophila),plasma membrane|membrane|integral component of membrane|chloride channel complex|,transport|ion transport|chloride transport|biological_process|,molecular_function|chloride channel activity|,10,0.2,0.442,10,0,0,0.2,0.355,0.355,0.699,0,0,-0.9,1.8
ENSMUSG00000037625,CLDN11,claudin 11,plasma membrane|integral component of plasma membrane|tight junction|tight junction|membrane|integral component of membrane|cell junction|basal part of cell|extracellular vesicular exosome|,cell adhesion|spermatogenesis|axon ensheathment|,structural molecule activity|protein binding|,10,0.2,0.581,10,-0.2,0.934,-0.1,0.354,-0.354,0.7,0,0,-1.6,1.3
ENSMUSG00000026556,VANGL2,"vang-like 2 (van gogh, Drosophila)",stress fiber|intracellular|plasma membrane|cell-cell junction|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|lateral plasma membrane|ER to Golgi transport vesicle|cell pole|cell periphery|,"patterning of blood vessels|establishment of planar polarity|establishment of planar polarity|neural tube closure|neural tube closure|hair follicle development|heart looping|outflow tract septum morphogenesis|membranous septum morphogenesis|muscular septum morphogenesis|epicardial cell to mesenchymal cell transition|planar cell polarity pathway involved in axis elongation|Rho protein signal transduction|multicellular organismal development|anterior/posterior pattern specification|convergent extension involved in neural plate elongation|convergent extension involved in neural plate elongation|regulation of Wnt signaling pathway|glomerulus development|regulation of actin cytoskeleton organization|somatic stem cell maintenance|nonmotile primary cilium assembly|non-canonical Wnt signaling pathway|cell migration involved in kidney development|post-anal tail morphogenesis|wound healing|positive regulation of JUN kinase activity|apical protein localization|establishment or maintenance of epithelial cell apical/basal polarity|somatic stem cell division|establishment of body hair planar orientation|digestive tract morphogenesis|convergent extension involved in axis elongation|convergent extension involved in organogenesis|Wnt signaling pathway, planar cell polarity pathway|Wnt signaling pathway, planar cell polarity pathway|inner ear receptor cell development|inner ear receptor stereocilium organization|inner ear receptor stereocilium organization|orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis|planar dichotomous subdivision of terminal units involved in lung branching morphogenesis|lateral sprouting involved in lung morphogenesis|cardiac vascular smooth muscle cell differentiation|kidney morphogenesis|planar cell polarity pathway involved in heart morphogenesis|cochlea development|cochlea morphogenesis|cochlea morphogenesis|establishment of epithelial cell polarity|regulation of establishment of planar polarity|establishment of planar polarity involved in neural tube closure|planar cell polarity pathway involved in neural tube closure|planar cell polarity pathway involved in neural tube closure|",protein binding|,10,-0.3,0.777,10,0.2,0.339,0.1,0.354,0.354,0.7,0,0,-1.6,1.2
ENSMUSG00000033214,SLITRK5,"SLIT and NTRK-like family, member 5",membrane|integral component of membrane|receptor complex|,synaptic transmission|axonogenesis|grooming behavior|response to xenobiotic stimulus|striatum development|adult behavior|skin development|dendrite morphogenesis|cardiovascular system development|,molecular_function|,10,-0.1,0.152,10,0.3,1.35,0.2,0.352,0.352,0.7,0,0,-1,1.7
ENSMUSG00000034723,TMX4,thioredoxin-related transmembrane protein 4,endoplasmic reticulum|membrane|integral component of membrane|,protein folding|transport|response to endoplasmic reticulum stress|cell redox homeostasis|oxidation-reduction process|,protein disulfide isomerase activity|,10,0,0,10,-0.4,1.5,-0.3,0.35,-0.35,0.701,0,0,-1.8,0.9
ENSMUSG00000060765,OLFR325,olfactory receptor 325,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.368,10,0.5,2.35,0.2,0.35,0.35,0.701,0,0,-0.9,1.7
ENSMUSG00000079157,FAM155A,"family with sequence similarity 155, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-1.2,3.55,-0.8,0.347,-0.347,0.702,0,0,-2,0.3
ENSMUSG00000059595,OLFR935,olfactory receptor 935,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,1.13,10,0,0,0.1,0.347,0.347,0.702,0,0,-1.5,1.4
ENSMUSG00000038267,SLC22A23,"solute carrier family 22, member 23",cellular_component|membrane|integral component of membrane|,transport|ion transport|transmembrane transport|,molecular_function|transporter activity|transmembrane transporter activity|,9,-0.3,1.14,9,0.2,0.562,0.2,0.344,0.344,0.704,0,0,-1.2,1.7
ENSMUSG00000026960,ARL6IP6,ADP-ribosylation factor-like 6 interacting protein 6,cellular_component|membrane|integral component of membrane|,biological_process|,protein binding|,10,-0.2,0.172,10,-0.5,0.267,-0.2,0.344,-0.344,0.704,0,0,-1.5,1.7
ENSMUSG00000060548,TNFRSF19,"tumor necrosis factor receptor superfamily, member 19",extracellular region|plasma membrane|membrane|integral component of membrane|,hair follicle development|positive regulation of I-kappaB kinase/NF-kappaB signaling|,None,10,0.1,0.438,10,-0.2,0.407,-0.2,0.34,-0.34,0.705,0,0,-1.2,1.8
ENSMUSG00000044528,TRAM1L1,translocation associated membrane protein 1-like 1,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,transport|protein transport|,molecular_function|,10,0.1,0.0813,10,0.2,0.367,0.1,0.339,0.339,0.706,0,0,-1.3,1.5
ENSMUSG00000018569,CLDN7,claudin 7,plasma membrane|tight junction|membrane|integral component of membrane|basolateral plasma membrane|lateral plasma membrane|cell junction|,None,structural molecule activity|protein binding|,10,0,0,10,0.4,1.1,0.2,0.33,0.33,0.71,0,0,-1.6,1.5
ENSMUSG00000022657,CD96,CD96 antigen,membrane|integral component of membrane|,cell adhesion|,None,10,-0.1,0.394,10,0.1,0.212,-0.1,0.327,-0.327,0.711,0,0,-1.4,1.4
ENSMUSG00000079659,TMEM243,"transmembrane protein 243, mitochondrial",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.8,2.76,0.3,0.322,0.322,0.713,0,0,-0.4,2
ENSMUSG00000063564,COL23A1,"collagen, type XXIII, alpha 1",collagen trimer|extracellular space|plasma membrane|cell surface|membrane|integral component of membrane|,protein homotrimerization|,heparin binding|protein homodimerization activity|,10,-0.1,0.00552,10,-0.4,0.729,-0.2,0.32,-0.32,0.714,0,0,-1.9,0.8
ENSMUSG00000020747,2310067B10RIK,RIKEN cDNA 2310067B10 gene,nucleus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.383,10,0.1,0.145,0.1,0.319,0.319,0.714,0,0,-0.7,2
ENSMUSG00000024667,TMEM216,transmembrane protein 216,cytoplasm|cytoskeleton|cilium|membrane|integral component of membrane|ciliary transition zone|TCTN-B9D complex|cell projection|,cell projection organization|cilium assembly|cilium morphogenesis|,molecular_function|,10,0,0,10,0.3,1.14,0.2,0.307,0.307,0.719,0,0,-0.6,2
ENSMUSG00000037140,TAS2R108,"taste receptor, type 2, member 108",cellular_component|plasma membrane|cilium|membrane|integral component of membrane|cell projection|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|respiratory gaseous exchange|response to stimulus|sensory perception of taste|detection of chemical stimulus involved in sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|bitter taste receptor activity|,10,0.2,1.33,10,0,0,0.1,0.306,0.306,0.72,0,0,-1.4,1.4
ENSMUSG00000050473,SLC35D3,"solute carrier family 35, member D3",membrane|integral component of membrane|,transport|carbohydrate transport|,None,10,0.4,0.543,10,-0.1,0.0274,-0.3,0.303,-0.303,0.721,0,0,-1.4,1.4
ENSMUSG00000026525,OPN3,opsin 3,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|phototransduction|protein-chromophore linkage|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|photoreceptor activity|,10,0.2,1.3,10,-1,0.805,0.1,0.302,0.302,0.721,0,0,-2,0.8
ENSMUSG00000074259,GRAMD2,GRAM domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.64,10,0,0,-0.1,0.302,-0.302,0.721,0,0,-1.9,0.9
ENSMUSG00000001014,ICAM4,"intercellular adhesion molecule 4, Landsteiner-Wiener blood group",extracellular region|extracellular space|cytoplasm|plasma membrane|membrane|integral component of membrane|,cell adhesion|single organismal cell-cell adhesion|,None,10,0.4,0.694,10,0,0,0.3,0.301,0.301,0.722,0,0,-0.8,2
ENSMUSG00000021703,SERINC5,serine incorporator 5,endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|myelin sheath|extracellular vesicular exosome|,lipid metabolic process|phosphatidylserine metabolic process|phospholipid biosynthetic process|myelination|positive regulation of transferase activity|,molecular_function|,10,0,0,10,0.2,0.631,0.1,0.3,0.3,0.722,0,0,-1.3,1.5
ENSMUSG00000030329,PIANP,PILR alpha associated neural protein,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.2,1.01,-0.1,0.293,-0.293,0.726,0,0,-1.4,1.5
ENSMUSG00000030207,8430419L09RIK,RIKEN cDNA 8430419L09 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.6,2.09,10,0,0,-0.3,0.291,-0.291,0.727,0,0,-2,0.7
ENSMUSG00000008318,RELT,RELT tumor necrosis factor receptor,cytoplasm|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,programmed cell death|,molecular_function|,10,-0.1,0.454,10,1.5,2.8,-0.2,0.291,-0.291,0.727,0,0,-0.9,2.9
ENSMUSG00000008140,EMC10,ER membrane protein complex subunit 10,extracellular region|membrane|integral component of membrane|ER membrane protein complex|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.729,-0.1,0.288,-0.288,0.728,0,0,-1.6,1.2
ENSMUSG00000073460,PNLDC1,poly(A)-specific ribonuclease (PARN)-like domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.862,-0.2,0.286,-0.286,0.729,0,0,-1.2,1.8
ENSMUSG00000051344,PLEKHM3,"pleckstrin homology domain containing, family M, member 3",cellular_component|,biological_process|intracellular signal transduction|,molecular_function|metal ion binding|,10,-0.1,0.0972,10,-0.1,0.213,-0.1,0.283,-0.283,0.73,0,0,-1.6,1.2
ENSMUSG00000031647,MFAP3L,microfibrillar-associated protein 3-like,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.5,2.43,0.3,0.281,0.281,0.731,0,0,-0.7,1.9
ENSMUSG00000050908,TVP23A,trans-golgi network vesicle protein 23A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.934,0.2,0.281,0.281,0.731,0,0,-0.9,1.9
ENSMUSG00000057454,LYPD3,Ly6/Plaur domain containing 3,extracellular space|plasma membrane|membrane|integral component of membrane|anchored component of membrane|,cellular component movement|cell-matrix adhesion|,laminin binding|,10,-0.2,0.36,10,-0.1,0.0759,-0.2,0.281,-0.281,0.731,0,0,-1.4,1.5
ENSMUSG00000041654,SLC39A11,"solute carrier family 39 (metal ion transporter), member 11",cellular_component|membrane|integral component of membrane|,transport|ion transport|zinc ion transport|biological_process|metal ion transport|transmembrane transport|,molecular_function|metal ion transmembrane transporter activity|,10,0.1,0.0136,10,0.1,0.293,0.1,0.28,0.28,0.732,0,0,-1.2,1.7
ENSMUSG00000039801,2410089E03RIK,RIKEN cDNA 2410089E03 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,1.8,3.68,1.8,0.276,0.276,0.734,0,0,-0.6,3
ENSMUSG00000037661,GPR160,G protein-coupled receptor 160,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.3,1.64,10,0.2,0.492,-0.2,0.275,-0.275,0.734,0,0,-1.6,1.1
ENSMUSG00000034591,SLC41A2,"solute carrier family 41, member 2",plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|,cation transmembrane transporter activity|,10,-0.3,1.06,10,0,0,-0.1,0.272,-0.272,0.735,0,0,-1.8,0.9
ENSMUSG00000044600,SMIM7,small integral membrane protein 7,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.171,10,-0.1,0.138,-0.1,0.271,-0.271,0.736,0,0,-1.7,1.5
ENSMUSG00000039313,AF529169,cDNA sequence AF529169,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.198,10,-0.1,0.0949,-0.1,0.267,-0.267,0.738,0,0,-1.7,1.1
ENSMUSG00000011118,PANX3,pannexin 3,plasma membrane|gap junction|membrane|integral component of membrane|cell junction|,transport|ion transport|cell-cell signaling|,None,10,-0.4,0.724,10,0,0,-0.2,0.266,-0.266,0.738,0,0,-1.7,1
ENSMUSG00000037577,EPHX3,epoxide hydrolase 3,cellular_component|extracellular region|,biological_process|,molecular_function|catalytic activity|hydrolase activity|,10,0,0,10,0.2,0.586,0.1,0.262,0.262,0.74,0,0,-1.6,1.3
ENSMUSG00000050394,ARMCX6,"armadillo repeat containing, X-linked 6",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.0122,10,0.2,0.449,0.1,0.262,0.262,0.74,0,0,-1.1,1.7
ENSMUSG00000029270,FAM69A,"family with sequence similarity 69, member A",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,protein binding|,10,-0.1,0.284,10,0.6,0.652,-0.1,0.261,-0.261,0.74,0,0,-0.9,1.9
ENSMUSG00000043857,MGAT5B,"mannoside acetylglucosaminyltransferase 5, isoenzyme B",Golgi apparatus|membrane|integral component of membrane|,protein N-linked glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|metal ion binding|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.1,0.134,10,-0.1,0.153,-0.1,0.261,-0.261,0.74,0,0,-1.3,1.7
ENSMUSG00000040836,GPR161,G protein-coupled receptor 161,plasma membrane|cilium|membrane|integral component of membrane|cell projection|recycling endosome|primary cilium|,signal transduction|G-protein coupled receptor signaling pathway|multicellular organismal development|positive regulation of cAMP biosynthetic process|negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|,signal transducer activity|G-protein coupled receptor activity|,10,-0.1,0.173,10,0.5,1.29,-0.1,0.259,-0.259,0.741,0,0,-1.2,1.8
ENSMUSG00000026258,3110079O15RIK,RIKEN cDNA 3110079O15 gene,membrane|integral component of membrane|cell periphery|,biological_process|,molecular_function|,10,0.2,0.512,10,0,0,0.1,0.258,0.258,0.742,0,0,-1.3,1.6
ENSMUSG00000063975,SLCO1A5,"solute carrier organic anion transporter family, member 1a5",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|brush border membrane|,amino acid transmembrane transport|transport|ion transport|lipid transport|organic anion transport|monocarboxylic acid transport|bile acid and bile salt transport|intestinal absorption|thyroid hormone transport|,transporter activity|monocarboxylic acid transmembrane transporter activity|organic anion transmembrane transporter activity|bile acid transmembrane transporter activity|thyroid hormone transmembrane transporter activity|,10,-0.1,0.334,10,0,0,-0.1,0.257,-0.257,0.742,0,0,-1.6,1.3
ENSMUSG00000013275,SLC41A1,"solute carrier family 41, member 1",cellular_component|membrane|integral component of membrane|,transport|ion transport|cation transport|biological_process|,molecular_function|cation transmembrane transporter activity|,10,-0.2,0.745,10,0,0,-0.1,0.256,-0.256,0.743,0,0,-1.7,1.1
ENSMUSG00000023153,TMEM52,transmembrane protein 52,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.701,-0.1,0.255,-0.255,0.743,0,0,-1.8,1
ENSMUSG00000024169,IFT140,intraflagellar transport 140,intracellular|cell|centrosome|cilium|cilium|axoneme|intraciliary transport particle A|intraciliary transport particle A|photoreceptor connecting cilium|ciliary basal body|ciliary basal body|cell projection|primary cilium|,intraciliary retrograde transport|intraciliary retrograde transport|cilium assembly|skeletal system morphogenesis|retina development in camera-type eye|cilium morphogenesis|protein localization to cilium|renal system development|regulation of cilium assembly|,molecular_function|,10,0.7,2.49,10,-0.4,1.17,0.1,0.252,0.252,0.744,0,0,-1.1,1.9
ENSMUSG00000000183,FGF6,fibroblast growth factor 6,extracellular region|sarcolemma|,cartilage condensation|angiogenesis|multicellular organismal development|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|cell differentiation|myoblast differentiation|positive regulation of cell division|,receptor binding|fibroblast growth factor receptor binding|growth factor activity|,10,0.1,0.212,10,-0.2,0.374,-0.1,0.251,-0.251,0.745,0,0,-1,1.8
ENSMUSG00000038212,HIATL1,hippocampus abundant transcript-like 1,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|transmembrane transport|,transporter activity|,10,-0.2,0.896,10,0,0,-0.1,0.251,-0.251,0.745,0,0,-1.7,1.1
ENSMUSG00000039917,RHBDD2,rhomboid domain containing 2,Golgi membrane|nucleus|Golgi apparatus|Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|,biological_process|,molecular_function|serine-type endopeptidase activity|,10,-0.2,0.663,10,0.3,1.38,0.2,0.25,0.25,0.745,0,0,-0.9,1.9
ENSMUSG00000050808,MUC15,mucin 15,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.591,-0.2,0.247,-0.247,0.747,0,0,-1.2,1.8
ENSMUSG00000019810,FUCA2,"fucosidase, alpha-L- 2, plasma",extracellular region|extracellular space|lysosome|extracellular vesicular exosome|,carbohydrate metabolic process|fucose metabolic process|metabolic process|response to bacterium|glycoside catabolic process|regulation of entry of bacterium into host cell|,"alpha-L-fucosidase activity|alpha-L-fucosidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|fucose binding|",10,0.1,0.388,10,-0.2,1.38,-0.1,0.243,-0.243,0.749,0,0,-1.1,1.8
ENSMUSG00000048534,AMICA1,"adhesion molecule, interacts with CXADR antigen 1",plasma membrane|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,immune system process|cell adhesion|heterophilic cell-cell adhesion|neutrophil chemotaxis|monocyte extravasation|gamma-delta T cell activation|positive regulation of epithelial cell proliferation involved in wound healing|neutrophil extravasation|,integrin binding|protein homodimerization activity|cell adhesion molecule binding|,10,0.1,0.469,10,0,0,0.1,0.241,0.241,0.75,0,0,-1.3,1.6
ENSMUSG00000051599,PCDHB2,protocadherin beta 2,plasma membrane|membrane|integral component of membrane|,cell adhesion|,molecular_function|,10,0.1,0.092,10,0.1,0.17,0.1,0.238,0.238,0.751,0,0,-1.3,1.6
ENSMUSG00000051373,PPAPDC3,phosphatidic acid phosphatase type 2 domain containing 3,nucleus|nuclear envelope|endoplasmic reticulum|membrane|integral component of membrane|,negative regulation of myotube differentiation|negative regulation of myotube differentiation|,"catalytic activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,-0.2,0.62,10,0.5,2.83,0.5,0.236,0.236,0.752,0,0,-0.9,1.8
ENSMUSG00000041037,IRGQ,"immunity-related GTPase family, Q",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.4,2.5,0.3,0.233,0.233,0.753,0,0,-1.2,1.6
ENSMUSG00000050201,OTOP2,otopetrin 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.272,10,0,0,-0.1,0.232,-0.232,0.754,0,0,-1.6,1.3
ENSMUSG00000050822,SLC29A4,"solute carrier family 29 (nucleoside transporters), member 4",plasma membrane|membrane|integral component of membrane|,transport|monoamine transport|transmembrane transport|,nucleoside transmembrane transporter activity|monoamine transmembrane transporter activity|,10,0,0,10,-1.3,3.46,-1.3,0.232,-0.232,0.754,0,0,-2,0.6
ENSMUSG00000041423,PAQR6,progestin and adipoQ receptor family member VI,cellular_component|membrane|integral component of membrane|,biological_process|,receptor activity|,10,-1.1,0.996,10,0.2,0.0914,-0.9,0.227,-0.227,0.756,0,0,-2,1.1
ENSMUSG00000035165,KCNE3,"potassium voltage-gated channel, Isk-related subfamily, gene 3",voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|regulation of potassium ion transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|potassium channel regulator activity|,10,0.2,1.46,10,-0.2,0.676,0.1,0.225,0.225,0.757,0,0,-1.3,1.5
ENSMUSG00000049307,FUT4,fucosyltransferase 4,Golgi apparatus|cell surface|membrane|integral component of membrane|cell periphery|,protein glycosylation|fucosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.2,0.48,10,-0.1,0.00602,0.1,0.223,0.223,0.758,0,0,-1.4,1.4
ENSMUSG00000025933,TMEM14A,transmembrane protein 14A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,0.355,10,-0.2,0.484,-0.1,0.223,-0.223,0.758,0,0,-1.5,1.4
ENSMUSG00000055912,TMEM150A,transmembrane protein 150A,plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.661,10,0.1,0.0506,-0.1,0.218,-0.218,0.76,0,0,-1.5,1.3
ENSMUSG00000025008,TCTN3,tectonic family member 3,membrane|integral component of membrane|extracellular vesicular exosome|,apoptotic process|smoothened signaling pathway|cell projection organization|cilium morphogenesis|,protein binding|,10,-0.8,2.42,10,0,0,-0.1,0.217,-0.217,0.76,0,0,-2,0.5
ENSMUSG00000029650,SLC46A3,"solute carrier family 46, member 3",membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|transmembrane transport|,molecular_function|,10,0,0,10,0.4,0.58,0.1,0.216,0.216,0.761,0,0,-1,1.9
ENSMUSG00000028786,TMEM54,transmembrane protein 54,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.3,1.98,0.3,0.215,0.215,0.761,0,0,-1.3,1.4
ENSMUSG00000056498,TMEM154,transmembrane protein 154,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.279,10,0.1,0.147,-0.1,0.214,-0.214,0.762,0,0,-1.7,1.2
ENSMUSG00000036744,OLFR701,olfactory receptor 701,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.322,10,0.1,0.0688,-0.1,0.209,-0.209,0.764,0,0,-1.4,1.4
ENSMUSG00000040432,LTB4R2,leukotriene B4 receptor 2,plasma membrane|membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|keratinocyte migration|,leukotriene B4 receptor activity|signal transducer activity|G-protein coupled receptor activity|leukotriene receptor activity|,10,0,0,10,0.2,0.534,0.1,0.206,0.206,0.766,0,0,-1.2,1.6
ENSMUSG00000041907,GPR45,G protein-coupled receptor 45,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,-0.1,0.345,-0.1,0.204,-0.204,0.767,0,0,-1.3,1.7
ENSMUSG00000090210,ITGA10,"integrin, alpha 10",membrane|integral component of membrane|,cell adhesion|integrin-mediated signaling pathway|,None,10,-0.3,0.69,10,0,0,-0.1,0.204,-0.204,0.767,0,0,-1.5,1.5
ENSMUSG00000096606,GM4980,predicted gene 4980,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.327,-0.1,0.201,-0.201,0.769,0,0,-1.5,1.4
ENSMUSG00000021592,ARSK,arylsulfatase K,cellular_component|extracellular region|,metabolic process|,catalytic activity|sulfuric ester hydrolase activity|hydrolase activity|alkyl sulfatase activity|endosulfan hemisulfate sulfatase activity|endosulfan sulfate hydrolase activity|metal ion binding|,9,-0.1,0.316,10,0.8,2.29,0.1,0.192,0.192,0.772,0,0,-0.7,2
ENSMUSG00000061549,OLFR301,olfactory receptor 301,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.101,10,0.1,0.105,0.1,0.187,0.187,0.774,0,0,-1.1,1.8
ENSMUSG00000036915,KIRREL2,kin of IRRE like 2 (Drosophila),plasma membrane|cell-cell junction|membrane|integral component of membrane|slit diaphragm|,negative regulation of protein phosphorylation|single organismal cell-cell adhesion|,protein binding|,10,-0.1,0.0356,10,-0.1,0.167,-0.1,0.184,-0.184,0.776,0,0,-1.5,1.4
ENSMUSG00000042498,D330045A20RIK,RIKEN cDNA D330045A20 gene,cellular_component|,biological_process|,poly(A) RNA binding|,10,-0.2,0.287,10,-0.1,0.0438,-0.3,0.182,-0.182,0.777,0,0,-1.4,1.7
ENSMUSG00000038024,DENND4C,DENN/MADD domain containing 4C,cytoplasm|cytosol|plasma membrane|membrane|retromer complex|cytoplasmic vesicle|insulin-responsive compartment|,transport|protein transport|positive regulation of Rab GTPase activity|cellular response to insulin stimulus|protein localization to plasma membrane|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.2,0.608,10,0,0,-0.2,0.177,-0.177,0.779,0,0,-1.7,1.1
ENSMUSG00000049123,CATSPERG2,catsper channel auxiliary subunit gamma 2,membrane|integral component of membrane|motile cilium|CatSper complex|sperm principal piece|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,protein binding|,10,0,0,10,-0.5,1.05,-0.1,0.177,-0.177,0.779,0,0,-2,0.6
ENSMUSG00000026442,NFASC,neurofascin,intracellular|plasma membrane|membrane|integral component of membrane|axon|paranodal junction|node of Ranvier|paranode region of axon|axon initial segment|extracellular vesicular exosome|Schwann cell microvillus|,protein localization to paranode region of axon|cell adhesion|axon guidance|peripheral nervous system development|transmission of nerve impulse|paranodal junction assembly|heterotypic cell-cell adhesion|myelination|clustering of voltage-gated sodium channels|synapse organization|protein localization to juxtaparanode region of axon|protein targeting to plasma membrane|,protein binding|protein domain specific binding|protein binding involved in heterotypic cell-cell adhesion|,10,-0.1,0.0752,10,-0.1,0.117,-0.1,0.175,-0.175,0.78,0,0,-1.7,1.1
ENSMUSG00000036510,CDH8,cadherin 8,plasma membrane|membrane|integral component of membrane|synaptic cleft|axon terminus|,"cell adhesion|homophilic cell adhesion|synaptic transmission|response to cold|synaptic transmission, glutamatergic|",calcium ion binding|metal ion binding|,10,1.1,0.367,10,-0.2,0.396,0.1,0.174,0.174,0.781,0,0,-1.4,1.9
ENSMUSG00000064105,CNNM2,cyclin M2,plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|,transport|ion transport|magnesium ion homeostasis|magnesium ion transport|,molecular_function|adenyl nucleotide binding|,10,0.1,0.271,10,-0.2,0.563,-0.1,0.173,-0.173,0.781,0,0,-1.7,1.1
ENSMUSG00000009731,KCND1,"potassium voltage-gated channel, Shal-related family, member 1",voltage-gated potassium channel complex|membrane|integral component of membrane|cell projection|neuronal cell body|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|metal ion binding|,10,0.1,0.259,10,0,0,0.1,0.171,0.171,0.782,0,0,-1.3,1.5
ENSMUSG00000037278,TMEM97,transmembrane protein 97,nucleus|lysosome|endoplasmic reticulum|rough endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|nuclear membrane|,cholesterol homeostasis|,molecular_function|,10,-0.5,0.123,10,-0.1,0.166,-0.1,0.17,-0.17,0.782,0,0,-1.9,1
ENSMUSG00000004612,NKG7,natural killer cell group 7 sequence,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.211,10,0,0,0.1,0.169,0.169,0.783,0,0,-1.9,1.1
ENSMUSG00000037752,XKR8,X Kell blood group precursor related family member 8 homolog,plasma membrane|membrane|integral component of membrane|,apoptotic process|engulfment of apoptotic cell|phosphatidylserine exposure on apoptotic cell surface|phosphatidylserine exposure on apoptotic cell surface|,molecular_function|,10,0,0,10,-0.2,0.385,-0.1,0.167,-0.167,0.784,0,0,-1.6,1.3
ENSMUSG00000051185,FAM174A,"family with sequence similarity 174, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.6,0.712,10,0.2,0.163,-0.2,0.166,-0.166,0.784,0,0,-1.9,1.1
ENSMUSG00000044950,PWWP2A,PWWP domain containing 2A,cellular_component|,biological_process|,molecular_function|,10,-0.6,0.965,10,0,0,-0.1,0.163,-0.163,0.786,0,0,-2,0.9
ENSMUSG00000017802,FAM134C,"family with sequence similarity 134, member C",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.347,10,0,0,-0.1,0.157,-0.157,0.789,0,0,-1.3,1.7
ENSMUSG00000027224,DUOXA1,dual oxidase maturation factor 1,endoplasmic reticulum membrane|plasma membrane|membrane|integral component of membrane|,transport|protein transport|hydrogen peroxide metabolic process|positive regulation of neuron differentiation|positive regulation of neuron differentiation|regulation of inflammatory response|positive regulation of reactive oxygen species metabolic process|regulation of thyroid hormone generation|,protein binding|,10,0,0,10,0.4,0.956,0.1,0.155,0.155,0.79,0,0,-1.3,1.7
ENSMUSG00000028631,KCNQ4,"potassium voltage-gated channel, subfamily Q, member 4",cytoplasm|plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|neuron projection|,"transport|ion transport|potassium ion transport|potassium ion transport|sensory perception of sound|negative regulation of synaptic transmission, dopaminergic|regulation of ion transmembrane transport|inner ear morphogenesis|transmembrane transport|potassium ion transmembrane transport|",ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.1,0.0319,10,0.1,0.137,0.1,0.154,0.154,0.79,0,0,-1,1.9
ENSMUSG00000045377,TMEM88,transmembrane protein 88,cellular_component|plasma membrane|membrane|integral component of membrane|,multicellular organismal development|biological_process|Wnt signaling pathway|,protein binding|,10,-0.2,0.118,10,-0.1,0.124,-0.2,0.15,-0.15,0.792,0,0,-1.8,0.9
ENSMUSG00000026721,RABGAP1L,RAB GTPase activating protein 1-like,nucleus|early endosome|Golgi apparatus|,regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|regulation of protein localization|megakaryocyte development|,GTPase activator activity|Rab GTPase activator activity|Rab GTPase binding|,10,-0.4,1.63,10,0.2,0.652,0.1,0.149,0.149,0.792,0,0,-1.7,1.2
ENSMUSG00000039747,ORAI2,ORAI calcium release-activated calcium modulator 2,membrane|integral component of membrane|growth cone|,None,None,10,0,0,10,0.3,0.799,0.3,0.148,0.148,0.793,0,0,-0.8,1.9
ENSMUSG00000025104,HDGFRP3,"hepatoma-derived growth factor, related protein 3",nucleus|nucleus|nucleus|cytoplasm|,cell proliferation|,chromatin binding|growth factor activity|,10,0,0,10,0.2,0.708,0.1,0.148,0.148,0.793,0,0,-1.1,1.7
ENSMUSG00000035773,KISS1R,KISS1 receptor,intracellular|plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|,activation of MAPKK activity|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|negative regulation of cell proliferation|negative regulation of cell proliferation|calcium-mediated signaling|negative regulation of cell migration|positive regulation of hormone secretion|arachidonic acid secretion|positive regulation of synaptic transmission|positive regulation of stress fiber assembly|,signal transducer activity|G-protein coupled receptor activity|protein binding|neuropeptide receptor activity|G-protein coupled peptide receptor activity|G-protein coupled peptide receptor activity|neuropeptide binding|,10,0.3,1.18,10,-0.1,0.515,0.1,0.145,0.145,0.794,0,0,-1.4,1.4
ENSMUSG00000045838,A430105I19RIK,RIKEN cDNA A430105I19 gene,cellular_component|,biological_process|,poly(A) RNA binding|,10,0,0,10,0.3,1.15,0.1,0.142,0.142,0.795,0,0,-0.8,1.9
ENSMUSG00000030431,TMEM238,transmembrane protein 238,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.03,10,-0.1,0.337,-0.1,0.137,-0.137,0.798,0,0,-1.5,1.3
ENSMUSG00000020829,SLC46A1,"solute carrier family 46, member 1",cytoplasm|plasma membrane|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|brush border membrane|,transport|folic acid transport|heme transport|methotrexate transport|transmembrane transport|,transporter activity|folic acid binding|folic acid transporter activity|heme transporter activity|methotrexate transporter activity|,10,0.1,0.464,10,0,0,0.1,0.135,0.135,0.799,0,0,-1.3,1.6
ENSMUSG00000045045,LRFN4,leucine rich repeat and fibronectin type III domain containing 4,membrane|integral component of membrane|,None,None,10,0,0,10,0.1,0.385,0.1,0.135,0.135,0.799,0,0,-1.3,1.6
ENSMUSG00000040189,CCDC114,coiled-coil domain containing 114,cilium|outer dynein arm|cell projection|,outer dynein arm assembly|,molecular_function|,10,0,0,10,-0.1,0.464,-0.1,0.123,-0.123,0.805,0,0,-1.7,1.2
ENSMUSG00000048799,CEP120,centrosomal protein 120,cytoplasm|centrosome|centrosome|cytoskeleton|,microtubule cytoskeleton organization|cell proliferation|cerebral cortex development|neurogenesis|interkinetic nuclear migration|astral microtubule organization|regulation of protein localization|regulation of microtubule-based process|,protein binding|protein C-terminus binding|,10,0.4,0.0985,10,-0.2,0.815,-0.1,0.119,-0.119,0.806,0,0,-1.4,1.5
ENSMUSG00000041889,SHISA4,shisa family member 4,membrane|integral component of membrane|,None,None,10,-0.1,0.127,10,-0.3,0.312,-0.1,0.117,-0.117,0.807,0,0,-1.8,1
ENSMUSG00000030683,SEZ6L2,seizure related 6 homolog like 2,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|neuronal cell body|,adult locomotory behavior|cerebellar Purkinje cell layer development|synapse maturation|regulation of protein kinase C signaling|,None,10,0,0,10,0.2,0.242,0.1,0.116,0.116,0.808,0,0,-0.8,2
ENSMUSG00000043964,ORAI3,ORAI calcium release-activated calcium modulator 3,membrane|integral component of membrane|,store-operated calcium entry|,None,10,0.1,0.228,10,0,0,0.1,0.116,0.116,0.808,0,0,-1.3,1.6
ENSMUSG00000066894,VSIG10,V-set and immunoglobulin domain containing 10,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.228,10,-0.2,0.631,-0.1,0.115,-0.115,0.808,0,0,-1.1,1.8
ENSMUSG00000048644,CTXN1,cortexin 1,cellular_component|membrane|integral component of membrane|intrinsic component of membrane|,biological_process|,molecular_function|,10,-0.1,0.255,10,0.2,0.0338,-0.1,0.104,-0.104,0.813,0,0,-0.9,2
ENSMUSG00000020105,LRIG3,leucine-rich repeats and immunoglobulin-like domains 3,extracellular space|plasma membrane|membrane|integral component of membrane|cytoplasmic vesicle|,multicellular organismal development|otolith morphogenesis|,None,10,0,0,10,0.2,0.545,0.1,0.103,0.103,0.814,0,0,-1.8,1.1
ENSMUSG00000064272,GPBAR1,G protein-coupled bile acid receptor 1,cytoplasm|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|bile acid signaling pathway|,signal transducer activity|G-protein coupled receptor activity|bile acid receptor activity|,10,-0.4,0.406,10,0,0,-0.1,0.101,-0.101,0.815,0,0,-1.9,1
ENSMUSG00000026070,IL18R1,interleukin 18 receptor 1,membrane|integral component of membrane|,signal transduction|natural killer cell activation|positive regulation of interferon-gamma production|interleukin-18-mediated signaling pathway|positive regulation of NF-kappaB import into nucleus|T-helper 1 cell differentiation|,interleukin-18 receptor activity|,10,-0.1,0.0162,10,-0.1,0.0896,-0.1,0.0963,-0.0963,0.817,0,0,-1.9,0.8
ENSMUSG00000071669,SNX29,sorting nexin 29,extracellular vesicular exosome|,biological_process|,molecular_function|phosphatidylinositol binding|,10,0.1,0.00315,10,-0.1,0.495,-0.1,0.0962,-0.0962,0.817,0,0,-1.5,1.5
ENSMUSG00000040680,KREMEN2,kringle containing transmembrane protein 2,membrane|integral component of membrane|,Wnt signaling pathway|,protein binding|,10,0.2,0.566,10,-0.3,0.17,0.1,0.0838,0.0838,0.822,0,0,-1.2,1.6
ENSMUSG00000036339,TMEM260,transmembrane protein 260,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.98,10,0,0,-0.2,0.0819,-0.0819,0.823,0,0,-1.5,1.4
ENSMUSG00000032128,ROBO3,roundabout homolog 3 (Drosophila),membrane|integral component of membrane|axon|,neuron migration|chemotaxis|multicellular organismal development|nervous system development|axon guidance|axon guidance|axon guidance|axon midline choice point recognition|cell differentiation|,protein binding|protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,0.6,0.659,-0.1,0.0753,-0.0753,0.826,0,0,-0.9,2
ENSMUSG00000044801,OLFR159,olfactory receptor 159,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|sensory perception of smell|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|olfactory receptor activity|,9,0,0,9,-0.2,0.351,-0.1,0.0697,-0.0697,0.829,0,0,-1.6,1.4
ENSMUSG00000023906,CLDN6,claudin 6,plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,cell-cell junction organization|,structural molecule activity|protein binding|,10,0,0,10,0.2,0.349,0.1,0.0676,0.0676,0.83,0,0,-1,1.8
ENSMUSG00000034224,SLC38A8,"solute carrier family 38, member 8",cellular_component|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|amino acid transport|biological_process|,molecular_function|,10,0,0,10,0.1,0.171,0.1,0.0656,0.0656,0.831,0,0,-1.5,1.4
ENSMUSG00000021803,CDHR1,cadherin-related family member 1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|photoreceptor outer segment membrane|,cell adhesion|homophilic cell adhesion|cellular process|photoreceptor cell maintenance|,calcium ion binding|protein binding|,10,-0.2,0.504,10,0.3,0.382,-0.1,0.0626,-0.0626,0.833,0,0,-1.3,1.6
ENSMUSG00000031486,GPR124,G protein-coupled receptor 124,plasma membrane|cell surface|membrane|integral component of membrane|,angiogenesis|sprouting angiogenesis|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|central nervous system development|positive regulation of endothelial cell migration|endothelial cell migration|regulation of angiogenesis|regulation of chemotaxis|regulation of establishment of blood-brain barrier|negative regulation of vascular endothelial growth factor signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0,0,10,-0.1,0.109,-0.1,0.0596,-0.0596,0.834,0,0,-1.9,0.9
ENSMUSG00000045980,TMEM104,transmembrane protein 104,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.6,2.09,10,0.2,0.291,-0.1,0.0571,-0.0571,0.835,0,0,-2,1
ENSMUSG00000033460,ARMCX1,"armadillo repeat containing, X-linked 1",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0277,10,-0.1,0.341,-0.1,0.055,-0.055,0.837,0,0,-1.4,1.5
ENSMUSG00000034520,GJC1,"gap junction protein, gamma 1",plasma membrane|gap junction|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,vasculogenesis|cell communication|cell-cell signaling|cell-cell signaling|synaptic transmission|heart development|visual perception|ion transmembrane transport|cell development|cardiac muscle tissue development|transmembrane transport|,ion channel activity|gap junction channel activity|protein binding|,10,-0.5,0.311,10,0.3,0.813,-0.1,0.0544,-0.0544,0.837,0,0,-1.5,1.6
ENSMUSG00000026347,TMEM163,transmembrane protein 163,endosome|membrane|integral component of membrane|cell junction|integral component of synaptic vesicle membrane|integral component of synaptic vesicle membrane|cytoplasmic vesicle|early endosome membrane|synapse|,biological_process|,zinc ion binding|,10,0.1,0.195,10,-0.1,0.176,0.1,0.054,0.054,0.837,0,0,-1.2,1.7
ENSMUSG00000021590,SPATA9,spermatogenesis associated 9,cellular_component|membrane|integral component of membrane|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,0.1,0.219,10,0,0,0.1,0.0509,0.0509,0.839,0,0,-1,1.9
ENSMUSG00000047197,GJD3,"gap junction protein, delta 3",plasma membrane|gap junction|connexon complex|connexon complex|connexon complex|cell surface|cell surface|membrane|integral component of membrane|cell junction|,cell communication|response to glucose|gap junction assembly|gap junction assembly|ion transmembrane transport|transmembrane transport|,ion channel activity|ion channel activity|gap junction channel activity|,10,0,0,10,0.3,0.42,0.2,0.0495,0.0495,0.839,0,0,-0.8,2
ENSMUSG00000032121,TMEM218,transmembrane protein 218,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.401,10,0,0,-0.1,0.0474,-0.0474,0.84,0,0,-1.4,1.5
ENSMUSG00000030917,TMEM159,transmembrane protein 159,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.236,10,0.2,0.512,0.1,0.046,0.046,0.841,0,0,-1.5,1.4
ENSMUSG00000032842,ABCC10,"ATP-binding cassette, sub-family C (CFTR/MRP), member 10",lysosomal membrane|plasma membrane|membrane|integral component of membrane|,transport|transmembrane transport|,"nucleotide binding|ATP binding|ATPase activity|ATPase activity, coupled to transmembrane movement of substances|",10,0.3,1.33,10,0,0,0.2,0.0452,0.0452,0.841,0,0,-1,1.8
ENSMUSG00000047881,RELL1,RELT-like 1,cytoplasm|plasma membrane|microtubule cytoskeleton|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.17,10,0,0,-0.1,0.0452,-0.0452,0.841,0,0,-1.6,1.5
ENSMUSG00000006301,TMBIM1,transmembrane BAX inhibitor motif containing 1,lysosome|lysosomal membrane|endosome|Golgi apparatus|endosome membrane|membrane|integral component of membrane|extracellular vesicular exosome|,negative regulation of establishment of protein localization to plasma membrane|negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of Fas signaling pathway|,death receptor binding|,10,0,0,10,-0.1,0.192,-0.1,0.0449,-0.0449,0.841,0,0,-1,2
ENSMUSG00000037977,6430571L13RIK,RIKEN cDNA 6430571L13 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.476,-0.1,0.0442,-0.0442,0.842,0,0,-1.8,1.1
ENSMUSG00000025348,ITGA7,integrin alpha 7,cytoplasm|muscle tendon junction|integrin complex|cell surface|membrane|integral component of membrane|neuromuscular junction|integrin alpha7-beta1 complex|integrin alpha7-beta1 complex|sarcolemma|,cell adhesion|cell adhesion|integrin-mediated signaling pathway|regulation of cell shape|cell migration|blood vessel morphogenesis|,integrin binding|protein binding|laminin binding|laminin binding|laminin binding|metal ion binding|protein heterodimerization activity|cell adhesion molecule binding|,10,0.1,0.393,10,-0.1,0.357,0.1,0.0419,0.0419,0.843,0,0,-1.3,1.6
ENSMUSG00000053647,GPER1,G protein-coupled estrogen receptor 1,intracellular|nucleus|nuclear envelope|cytoplasm|cytoplasm|mitochondrion|endosome|early endosome|endoplasmic reticulum|Golgi apparatus|trans-Golgi network|cytoskeleton|plasma membrane|plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|axon|dendrite|cytoplasmic vesicle membrane|cytoplasmic vesicle|mitochondrial membrane|dendritic spine membrane|presynaptic membrane|cell projection|dendritic shaft|axon terminus|dendritic spine head|keratin filament|synapse|postsynaptic membrane|perinuclear region of cytoplasm|presynaptic active zone|recycling endosome|neuronal postsynaptic density|,positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|immune system process|negative regulation of leukocyte activation|transcription from RNA polymerase II promoter|apoptotic process|inflammatory response|cell cycle|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|nervous system development|positive regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of gene expression|negative regulation of gene expression|positive regulation of phosphatidylinositol 3-kinase signaling|cell differentiation|apoptotic chromosome condensation|nuclear fragmentation involved in apoptotic nuclear change|positive regulation of cell migration|intracellular steroid hormone receptor signaling pathway|positive regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|mineralocorticoid receptor signaling pathway|positive regulation of insulin secretion|positive regulation of inositol trisphosphate biosynthetic process|positive regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|steroid hormone mediated signaling pathway|steroid hormone mediated signaling pathway|positive regulation of MAPK cascade|innate immune response|negative regulation of fat cell differentiation|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of epidermal growth factor receptor signaling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|positive regulation of vasodilation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of inflammatory response|positive regulation of neurogenesis|negative regulation of DNA metabolic process|negative regulation of lipid biosynthetic process|positive regulation of release of sequestered calcium ion into cytosol|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|positive regulation of uterine smooth muscle contraction|negative regulation of cell cycle arrest|cellular response to glucose stimulus|cellular response to tumor necrosis factor|cellular response to peptide hormone stimulus|cellular response to mineralocorticoid stimulus|cellular response to estradiol stimulus|cellular response to estradiol stimulus|positive regulation of establishment of protein localization to plasma membrane|positive regulation of release of cytochrome c from mitochondria|positive regulation of endothelial cell apoptotic process|positive regulation of extrinsic apoptotic signaling pathway|,chromatin binding|steroid hormone receptor activity|signal transducer activity|G-protein coupled receptor activity|steroid binding|drug binding|mineralocorticoid receptor activity|estrogen receptor activity|estrogen receptor activity|hormone binding|,10,0,0,10,-0.1,0.184,-0.1,0.0395,-0.0395,0.844,0,0,-1.7,1.2
ENSMUSG00000021969,ZDHHC20,"zinc finger, DHHC domain containing 20",plasma membrane|membrane|membrane|integral component of membrane|,protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,-0.1,0.164,10,0,0,-0.1,0.0389,-0.0389,0.844,0,0,-1.1,2
ENSMUSG00000071147,TAS2R140,"taste receptor, type 2, member 140",membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|taste receptor activity|bitter taste receptor activity|,10,-0.1,0.0646,10,0.2,0.265,0.1,0.0367,0.0367,0.845,0,0,-1.4,1.5
ENSMUSG00000055296,TMEM245,transmembrane protein 245,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,0.213,10,-0.2,0.515,-0.1,0.0357,-0.0357,0.845,0,0,-1,1.9
ENSMUSG00000040035,DISP2,dispatched homolog 2 (Drosophila),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.129,0.1,0.0325,0.0325,0.847,0,0,-1.5,1.4
ENSMUSG00000019990,PDE7B,phosphodiesterase 7B,None,signal transduction|metabolic process|,"3',5'-cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|",10,-0.1,0.074,10,0.1,0.00818,-0.1,0.0296,-0.0296,0.848,0,0,-1.6,1.3
ENSMUSG00000024681,MS4A3,"membrane-spanning 4-domains, subfamily A, member 3",cytoplasm|membrane|integral component of membrane|,biological_process|,protein binding|,10,0,0,10,0.3,0.188,0.1,0.0232,0.0232,0.851,0,0,-1,1.9
ENSMUSG00000069808,FAM57A,"family with sequence similarity 57, member A",cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.7,0.549,0.1,0.0194,0.0194,0.853,0,0,-0.6,2
ENSMUSG00000041707,1810011H11RIK,RIKEN cDNA 1810011H11 gene,cellular_component|,biological_process|,molecular_function|,7,0.3,0.204,7,-0.1,0.034,0.1,0.0173,0.0173,0.854,0,0,-1.1,2
ENSMUSG00000047996,PRRG1,proline rich Gla (G-carboxyglutamic acid) 1,cellular_component|,biological_process|,molecular_function|,10,-0.7,1.75,10,0.2,0.344,-0.1,0.0154,-0.0154,0.855,0,0,-2,0.7
ENSMUSG00000042035,IGSF3,"immunoglobulin superfamily, member 3",cellular_component|membrane|integral component of membrane|,lacrimal gland development|,molecular_function|,10,0,0,10,0.2,0.493,0.1,0.0139,0.0139,0.855,0,0,-1.4,1.5
ENSMUSG00000038984,TSPYL5,"testis-specific protein, Y-encoded-like 5",cellular_component|nucleus|,nucleosome assembly|positive regulation of cell proliferation|positive regulation of protein ubiquitination|regulation of growth|positive regulation of protein kinase B signaling|cellular response to gamma radiation|,molecular_function|,10,-0.1,0.229,10,0.2,0.305,0.1,0.012,0.012,0.856,0,0,-1.4,1.5
ENSMUSG00000071648,ROM1,rod outer segment membrane protein 1,photoreceptor outer segment|membrane|integral component of membrane|photoreceptor outer segment membrane|,cell adhesion|visual perception|regulation of gene expression|retina morphogenesis in camera-type eye|camera-type eye photoreceptor cell differentiation|retina vasculature development in camera-type eye|,molecular_function|,9,0.1,0.276,9,0,0,-0.1,0.00739,-0.00739,0.858,0,0,-1.6,1.4
ENSMUSG00000007594,HAPLN4,hyaluronan and proteoglycan link protein 4,cellular_component|extracellular region|proteinaceous extracellular matrix|,cell adhesion|biological_process|,hyaluronic acid binding|,10,0,0,10,0.3,0.279,0.1,0.00703,0.00703,0.858,0,0,-1.4,1.5
ENSMUSG00000009246,TRPM5,"transient receptor potential cation channel, subfamily M, member 5",plasma membrane|membrane|integral component of membrane|,transport|ion transport|ion transmembrane transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|potassium ion transmembrane transport|,calcium activated cation channel activity|voltage-gated ion channel activity|potassium channel activity|sodium channel activity|,10,-0.1,0.228,10,0,0,-0.1,0.00646,-0.00646,0.859,0,0,-1.5,1.5
ENSMUSG00000048218,AMIGO2,adhesion molecule with Ig like domain 2,nucleus|plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|heterophilic cell-cell adhesion|negative regulation of apoptotic process|negative regulation of programmed cell death|negative regulation of programmed cell death|,molecular_function|,10,-0.2,0.443,10,0.1,0.281,-0.1,0.00395,-0.00395,0.86,0,0,-0.9,1.9
ENSMUSG00000044197,GPR146,G protein-coupled receptor 146,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.1,0.119,10,0.2,0.072,-0.1,0.00196,-0.00196,0.861,0,0,-1.5,1.5
ENSMUSG00000025956,METTL21A,methyltransferase like 21A,cellular_component|cytoplasm|,protein methylation|peptidyl-lysine methylation|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|Hsp70 protein binding|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|ATPase binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0,0,0,0,0,0.861,0,0,-1.4,1.7
ENSMUSG00000050947,AMIGO1,adhesion molecule with Ig like domain 1,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|heterophilic cell-cell adhesion|multicellular organismal development|nervous system development|axonogenesis|axonal fasciculation|axonal fasciculation|cell differentiation|myelination|positive regulation of axonogenesis|positive regulation of axonogenesis|,protein binding|,10,-0.1,0.414,10,-1.4,2.61,0,0,0,0.861,0,0,-2,0.6
ENSMUSG00000000706,BTN1A1,"butyrophilin, subfamily 1, member A1",extracellular space|membrane|integral component of membrane|,negative regulation of cellular metabolic process|negative regulation of activated T cell proliferation|negative regulation of cytokine secretion|,protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000067787,BLCAP,bladder cancer associated protein homolog (human),membrane|integral component of membrane|,apoptotic process|cell cycle|apoptotic nuclear changes|,None,10,-0.1,0.282,10,0.3,0.862,0,0,0,0.861,0,0,-1.4,1.5
ENSMUSG00000036814,SLC6A20A,"solute carrier family 6 (neurotransmitter transporter), member 20A",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|apical plasma membrane|,amino acid transmembrane transport|amino acid transmembrane transport|transport|neurotransmitter transport|amino acid transport|amino acid transport|glycine transport|proline transport|,neurotransmitter:sodium symporter activity|amino acid transmembrane transporter activity|amino acid transmembrane transporter activity|symporter activity|,10,0.1,0.307,10,-0.5,1.4,0,0,0,0.861,0,0,-1.9,1
ENSMUSG00000035270,IMPG2,interphotoreceptor matrix proteoglycan 2,proteinaceous extracellular matrix|membrane|integral component of membrane|receptor complex|,biological_process|,hyaluronic acid binding|heparin binding|,10,-0.1,0.045,10,1.6,1.11,0,0,0,0.861,0,0,-0.7,3
ENSMUSG00000022686,B3GNT5,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5",intracellular|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|multicellular organismal development|central nervous system development|lipopolysaccharide biosynthetic process|sphingolipid biosynthetic process|,"galactosyltransferase activity|beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity|lipopolysaccharide N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity|",10,0,0,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000038745,NLRP6,"NLR family, pyrin domain containing 6",cellular_component|nucleus|cytoplasm|plasma membrane|membrane|,G-protein coupled receptor signaling pathway|response to bacterium|negative regulation of toll-like receptor signaling pathway|wound healing|negative regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of MAPK cascade|regulation of inflammatory response|negative regulation of immune response|,nucleotide binding|vasopressin receptor activity|ATP binding|peptide binding|,10,0.1,0.364,10,0,0,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000028132,TMEM56,transmembrane protein 56,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.449,10,0.2,0.248,0,0,0,0.861,0,0,-1.3,1.6
ENSMUSG00000031990,JAM3,junction adhesion molecule 3,extracellular region|extracellular space|plasma membrane|cell-cell junction|tight junction|cell surface|membrane|integral component of membrane|cell junction|desmosome|paranodal junction|Schmidt-Lanterman incisure|cell-cell contact zone|,angiogenesis|angiogenesis|neutrophil homeostasis|adaptive immune response|myeloid progenitor cell differentiation|leukocyte migration involved in inflammatory response|cell adhesion|cell adhesion|cell adhesion|cell-matrix adhesion|cell-matrix adhesion|spermatogenesis|spermatid development|cell migration|transmission of nerve impulse|establishment of cell polarity|myelination|regulation of neutrophil chemotaxis|regulation of actin cytoskeleton organization by cell-cell adhesion|,integrin binding|integrin binding|protein binding|protein homodimerization activity|protein heterodimerization activity|,10,0.2,0.316,10,-0.1,0.273,0,0,0,0.861,0,0,-0.9,2
ENSMUSG00000067722,BC003965,cDNA sequence BC003965,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.0579,10,0,0,0,0,0,0.861,0,0,-1.5,1.4
ENSMUSG00000031951,TMEM231,transmembrane protein 231,plasma membrane|cilium|membrane|integral component of membrane|ciliary transition zone|TCTN-B9D complex|cell projection|ciliary membrane|,in utero embryonic development|vasculature development|smoothened signaling pathway|cell projection organization|regulation of protein localization|cilium assembly|embryonic digit morphogenesis|camera-type eye development|neuroepithelial cell differentiation|,protein binding|,10,0,0,10,0.8,2.43,0,0,0,0.861,0,0,-1.4,1.9
ENSMUSG00000046908,LTB4R1,leukotriene B4 receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,leukotriene B4 receptor activity|signal transducer activity|G-protein coupled receptor activity|leukotriene receptor activity|,10,0,0,10,-0.2,0.23,0,0,0,0.861,0,0,-1.9,1
ENSMUSG00000078771,EVI2A,ecotropic viral integration site 2a,membrane|integral component of membrane|,None,None,10,0,0,10,0.1,0.275,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000036826,IGFLR1,IGF-like family receptor 1,plasma membrane|plasma membrane|membrane|integral component of membrane|,biological_process|,protein binding|,10,0,0,10,-0.1,0.271,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000036975,TMEM177,transmembrane protein 177,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.8,1.2
ENSMUSG00000034210,EFCAB14,EF-hand calcium binding domain 14,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0.3,0.834,0,0,0,0.861,0,0,-1.5,1.6
ENSMUSG00000081534,SLC48A1,"solute carrier family 48 (heme transporter), member 1",cellular_component|lysosome|endosome|membrane|integral component of membrane|,transport|biological_process|heme transport|,molecular_function|heme transporter activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.5
ENSMUSG00000049036,TMEM121,transmembrane protein 121,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0921,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000036026,TMEM63B,transmembrane protein 63b,cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,nucleotide binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.4,1.7
ENSMUSG00000033152,PODXL2,podocalyxin-like 2,cellular_component|membrane|integral component of membrane|,cell adhesion|leukocyte tethering or rolling|,molecular_function|,10,0.2,0.509,10,0,0,0,0,0,0.861,0,0,-1.9,1.2
ENSMUSG00000007888,CRLF1,cytokine receptor-like factor 1,extracellular region|CRLF-CLCF1 complex|,positive regulation of cell proliferation|positive regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of neuron apoptotic process|negative regulation of motor neuron apoptotic process|,cytokine activity|ciliary neurotrophic factor receptor binding|ciliary neurotrophic factor receptor binding|cytokine binding|protein heterodimerization activity|protein heterodimerization activity|,10,0.6,0.503,10,0,0,0,0,0,0.861,0,0,-1,1.9
ENSMUSG00000062372,OTOF,otoferlin,cell|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|cell junction|synaptic vesicle membrane|cytoplasmic vesicle|synapse|,sensory perception of sound|synaptic vesicle exocytosis|synaptic vesicle exocytosis|,calcium ion binding|protein binding|AP-2 adaptor complex binding|,10,-0.2,0.0458,10,0.6,1.27,0,0,0,0.861,0,0,-0.9,2
ENSMUSG00000049649,GPR3,G-protein coupled receptor 3,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cAMP metabolic process|regulation of meiosis|,signal transducer activity|G-protein coupled receptor activity|,10,0.2,0.119,10,-0.3,0.729,0,0,0,0.861,0,0,-1.6,1.3
ENSMUSG00000037490,SLC2A12,"solute carrier family 2 (facilitated glucose transporter), member 12",membrane|integral component of membrane|,transport|carbohydrate transport|glucose transport|transmembrane transport|,molecular_function|transporter activity|transmembrane transporter activity|substrate-specific transmembrane transporter activity|,10,0.4,0.682,10,0,0,0,0,0,0.861,0,0,-1.1,1.8
ENSMUSG00000028782,BAI2,brain-specific angiogenesis inhibitor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|peripheral nervous system development|negative regulation of angiogenesis|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|,10,0.1,0.154,10,-0.1,0.138,0,0,0,0.861,0,0,-0.9,2
ENSMUSG00000043953,CCRL2,chemokine (C-C motif) receptor-like 2,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,chemotaxis|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|C-C chemokine receptor activity|chemokine receptor binding|chemokine receptor binding|CCR chemokine receptor binding|,10,0,0,10,-0.2,0.0451,0,0,0,0.861,0,0,-1.8,1.2
ENSMUSG00000029070,MXRA8,matrix-remodelling associated 8,cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.1,0.0566,10,0,0,0,0,0,0.861,0,0,-1.9,1.1
ENSMUSG00000045312,LHFPL2,lipoma HMGIC fusion partner-like 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.133,0,0,0,0.861,0,0,-1.5,1.6
ENSMUSG00000075289,CARNS1,carnosine synthase 1,cellular_component|,ATP catabolic process|ATP catabolic process|carnosine biosynthetic process|carnosine biosynthetic process|,nucleotide binding|ATP binding|ligase activity|ATPase activity|ATPase activity|metal ion binding|carnosine synthase activity|carnosine synthase activity|,10,1.2,1.09,10,0,0,0,0,0,0.861,0,0,-0.9,2
ENSMUSG00000020282,RHBDF1,rhomboid family 1 (Drosophila),Golgi membrane|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|membrane|integral component of membrane|,proteolysis|cell proliferation|cell migration|regulation of epidermal growth factor receptor signaling pathway|regulation of protein secretion|negative regulation of protein secretion|regulation of proteasomal protein catabolic process|,serine-type endopeptidase activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.5,1.6
ENSMUSG00000036186,FAM69B,"family with sequence similarity 69, member B",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.3,0.278,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000031534,SMIM19,small integral membrane protein 19,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000031904,SLC7A6,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 6",plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|,molecular_function|amino acid transmembrane transporter activity|antiporter activity|,10,0,0,10,0.1,0.0652,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000032641,GPR19,G protein-coupled receptor 19,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.2,0.201,10,-0.2,0.472,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000046961,GPR156,G protein-coupled receptor 156,plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,signal transduction|G-protein coupled receptor signaling pathway|,molecular_function|signal transducer activity|G-protein coupled receptor activity|G-protein coupled GABA receptor activity|,10,0.3,0.636,10,0,0,0,0,0,0.861,0,0,-1.2,1.7
ENSMUSG00000038963,SLCO4A1,"solute carrier organic anion transporter family, member 4a1",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|ion transport|organic anion transport|thyroid hormone metabolic process|thyroid hormone transport|,transporter activity|organic anion transmembrane transporter activity|thyroid hormone transmembrane transporter activity|,10,-0.1,0.141,10,0.1,0.0778,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000038732,MBOAT1,membrane bound O-acyltransferase domain containing 1,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,lipid metabolic process|biological_process|phospholipid biosynthetic process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,-0.1,0.0503,10,0.4,0.956,0,0,0,0.861,0,0,-1.1,1.8
ENSMUSG00000026069,IL1RL1,interleukin 1 receptor-like 1,extracellular region|extracellular space|plasma membrane|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|extracellular matrix|,negative regulation of T-helper 1 type immune response|signal transduction|negative regulation of cell proliferation|negative regulation of interferon-gamma production|positive regulation of interleukin-5 production|interleukin-33-mediated signaling pathway|positive regulation of macrophage activation|negative regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of inflammatory response|positive regulation of chemokine secretion|,interleukin-33 binding|interleukin-33 receptor activity|interleukin-1 receptor activity|,10,-0.1,0.0548,10,0.1,0.064,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000054942,FAM73A,"family with sequence similarity 73, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.495,10,0,0,0,0,0,0.861,0,0,-1.4,1.5
ENSMUSG00000051855,MEST,mesoderm specific transcript,endoplasmic reticulum|membrane|integral component of membrane|extracellular vesicular exosome|,regulation of lipid storage|response to retinoic acid|,catalytic activity|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,-0.2,0.136,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000034482,LY6G5C,"lymphocyte antigen 6 complex, locus G5C",cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1,2
ENSMUSG00000027495,FAM210B,"family with sequence similarity 210, member B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000030584,DPF1,"D4, zinc and double PHD fingers family 1",nucleus|cytoplasm|nBAF complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|nervous system development|",nucleic acid binding|zinc ion binding|metal ion binding|,10,-0.2,0.261,10,0,0,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000028040,EFNA4,ephrin A4,plasma membrane|membrane|anchored component of membrane|,axon guidance|osteoclast differentiation|bone remodeling|ephrin receptor signaling pathway|,ephrin receptor binding|ephrin receptor binding|,10,-0.1,0.0168,10,0.1,0.206,0,0,0,0.861,0,0,-1.8,1.1
ENSMUSG00000027505,FAM209,family with sequence similarity 209,nucleus|,biological_process|,molecular_function|,10,0.1,0.138,10,0,0,0,0,0,0.861,0,0,-1.8,1.3
ENSMUSG00000024425,NDFIP1,Nedd4 family interacting protein 1,extracellular region|endosome|Golgi apparatus|cell cortex|membrane|integral component of membrane|integral component of Golgi membrane|perinuclear region of cytoplasm|,regulation of myeloid leukocyte differentiation|negative regulation of type 2 immune response|cellular iron ion homeostasis|signal transduction|negative regulation of gene expression|positive regulation of protein ubiquitination|negative regulation of transporter activity|negative regulation of interleukin-4 production|negative regulation of T cell proliferation|positive regulation of I-kappaB kinase/NF-kappaB signaling|ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway|regulation of lymphocyte differentiation|positive regulation of protein catabolic process|positive regulation of protein catabolic process|negative regulation of isotype switching to IgE isotypes|regulation of isotype switching to IgG isotypes|negative regulation of inflammatory response|negative regulation of protein transport|,signal transducer activity|protein binding|WW domain binding|,10,0,0,10,-0.1,0.0576,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000014786,SLC9A5,"solute carrier family 9 (sodium/hydrogen exchanger), member 5",cellular_component|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|proton transport|sodium ion transmembrane transport|hydrogen ion transmembrane transport|,antiporter activity|sodium:proton antiporter activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1,1.9
ENSMUSG00000022215,FITM1,fat storage-inducing transmembrane protein 1,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,positive regulation of sequestering of triglyceride|lipid particle organization|,None,10,0,0,10,0.2,0.0591,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000034739,MFRP,membrane-type frizzled-related protein,None,visual perception|eye photoreceptor cell development|retina development in camera-type eye|,None,10,-0.1,0.328,10,0.6,0.931,0,0,0,0.861,0,0,-0.9,2
ENSMUSG00000031772,CNTNAP4,contactin associated protein-like 4,membrane|integral component of membrane|dendrite|,cell adhesion|,protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000090491,FRYL,furry homolog-like (Drosophila),cellular_component|,biological_process|,protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000001029,ICAM2,intercellular adhesion molecule 2,uropod|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|cell periphery|,cell adhesion|single organismal cell-cell adhesion|,integrin binding|protein binding|,10,0.4,0.34,10,-0.1,0.196,0,0,0,0.861,0,0,-1,1.9
ENSMUSG00000020793,GALR2,galanin receptor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|synaptic transmission|neuron projection development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of large conductance calcium-activated potassium channel activity|,signal transducer activity|G-protein coupled receptor activity|galanin receptor activity|peptide hormone binding|neuropeptide binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.5
ENSMUSG00000030124,LAG3,lymphocyte-activation gene 3,external side of plasma membrane|membrane|integral component of membrane|,cell surface receptor signaling pathway|negative regulation of interleukin-2 biosynthetic process|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|negative regulation of T cell activation|,transmembrane signaling receptor activity|MHC class II protein binding|MHC class II protein binding|,9,-0.2,0.359,9,0.2,0.0838,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000055976,CLDN23,claudin 23,cellular_component|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,biological_process|,molecular_function|structural molecule activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000086564,CD101,CD101 antigen,membrane|integral component of membrane|extracellular vesicular exosome|,positive regulation of myeloid leukocyte differentiation|,molecular_function|,10,0.1,0.262,10,0,0,0,0,0,0.861,0,0,-1.4,1.5
ENSMUSG00000022801,LRCH3,leucine-rich repeats and calponin homology (CH) domain containing 3,extracellular region|cytoplasm|,biological_process|,molecular_function|,10,-0.2,0.109,10,0.5,0.283,0,0,0,0.861,0,0,-1.4,1.7
ENSMUSG00000029431,B3GNT4,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4",cellular_component|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,-0.1,0.117,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000031953,TMEM170,transmembrane protein 170,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.364,10,0.1,0.186,0,0,0,0.861,0,0,-1.5,1.4
ENSMUSG00000070720,TMEM200B,transmembrane protein 200B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.129,0,0,0,0.861,0,0,-1.2,1.7
ENSMUSG00000026514,CNIH3,cornichon homolog 3 (Drosophila),plasma membrane|membrane|integral component of membrane|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|dendritic shaft|synapse|postsynaptic membrane|,"synaptic transmission, glutamatergic|intracellular signal transduction|regulation of membrane potential|localization within membrane|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|",channel regulator activity|,10,0.2,0.297,10,0,0,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000049686,ORAI1,ORAI calcium release-activated calcium modulator 1,plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|growth cone|protein complex|,store-operated calcium entry|store-operated calcium entry|immune system process|transport|ion transport|calcium ion transport|regulation of calcium ion transport|positive regulation of calcium ion transport|calcium ion transmembrane transport|,calcium channel activity|protein binding|calmodulin binding|store-operated calcium channel activity|,10,0,0,10,0.1,0.0751,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000061461,SMIM20,small integral membrane protein 20,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.831,10,0,0,0,0,0,0.861,0,0,-1.8,1
ENSMUSG00000059674,CDH24,cadherin-like 24,plasma membrane|cell-cell junction|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|single organismal cell-cell adhesion|,calcium ion binding|beta-catenin binding|alpha-catenin binding|metal ion binding|delta-catenin binding|,10,0.1,0.0814,10,0,0,0,0,0,0.861,0,0,-1.2,1.7
ENSMUSG00000034028,CD226,CD226 antigen,external side of plasma membrane|cell surface|membrane|integral component of membrane|,cytokine production|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|positive regulation of immunoglobulin mediated immune response|cell adhesion|positive regulation of mast cell activation|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of Fc receptor mediated stimulatory signaling pathway|,integrin binding|protein binding|protein kinase binding|cell adhesion molecule binding|,10,0.1,0.182,10,0,0,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000057722,LEPR,leptin receptor,extracellular region|extracellular space|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,angiogenesis|signal transduction|G-protein coupled receptor signaling pathway|cholesterol metabolic process|regulation of metabolic process|leptin-mediated signaling pathway|eating behavior|positive regulation of MAPK cascade|negative regulation of gluconeogenesis|negative regulation of hydrolase activity|,transmembrane signaling receptor activity|cytokine receptor activity|protein binding|protein-hormone receptor activity|peptide hormone binding|identical protein binding|,10,-0.2,0.271,10,0.2,0.0766,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000044345,MARVELD1,MARVEL (membrane-associating) domain containing 1,cellular_component|nucleus|cytoplasm|cytoskeleton|plasma membrane|membrane|integral component of membrane|,cell cycle|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.3
ENSMUSG00000056569,MPZ,myelin protein zero,plasma membrane|membrane|integral component of membrane|,cell-cell junction maintenance|,protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.5,1.4
ENSMUSG00000032434,CMTM6,CKLF-like MARVEL transmembrane domain containing 6,extracellular space|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,chemotaxis|biological_process|,molecular_function|cytokine activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.7,1.2
ENSMUSG00000047033,PCDHB15,protocadherin beta 15,plasma membrane|membrane|integral component of membrane|,cell adhesion|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1,2
ENSMUSG00000029784,SSMEM1,serine-rich single-pass membrane protein 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.827,0,0,0,0.861,0,0,-1.9,0.9
ENSMUSG00000073998,OLFR520,olfactory receptor 520,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0942,10,0,0,0,0,0,0.861,0,0,-1.6,1.3
ENSMUSG00000019891,DCBLD1,"discoidin, CUB and LCCL domain containing 1",membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000044788,FADS6,"fatty acid desaturase domain family, member 6",cellular_component|membrane|integral component of membrane|,lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|biological_process|oxidation-reduction process|,molecular_function|acyl-CoA desaturase activity|oxidoreductase activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000057060,SLC35F3,"solute carrier family 35, member F3",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0,0,10,-0.4,0.844,0,0,0,0.861,0,0,-1.5,1.3
ENSMUSG00000028152,TSPAN5,tetraspanin 5,plasma membrane|membrane|integral component of membrane|,positive regulation of Notch signaling pathway|protein maturation|protein maturation|establishment of protein localization to plasma membrane|,enzyme binding|enzyme binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000024059,CLIP4,"CAP-GLY domain containing linker protein family, member 4",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.4,1.13,0,0,0,0.861,0,0,-1.8,1
ENSMUSG00000071180,SMIM15,small integral membrane protein 15,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.3
ENSMUSG00000030167,KLRC1,"killer cell lectin-like receptor subfamily C, member 1",external side of plasma membrane|,None,None,10,-0.1,0.0887,10,0,0,0,0,0,0.861,0,0,-1,2
ENSMUSG00000010307,TMEM86A,transmembrane protein 86A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.5,0.0744,0,0,0,0.861,0,0,-1.1,2
ENSMUSG00000028360,SLC44A5,"solute carrier family 44, member 5",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0178,0,0,0,0.861,0,0,-1.1,1.9
ENSMUSG00000050761,GP1BB,"glycoprotein Ib, beta polypeptide",integral component of plasma membrane|membrane|integral component of membrane|,cell adhesion|blood coagulation|hemostasis|,None,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000028347,TMEFF1,transmembrane protein with EGF-like and two follistatin-like domains 1,plasma membrane|membrane|integral component of membrane|,multicellular organismal development|,None,10,-0.1,0.294,10,0.2,0.494,0,0,0,0.861,0,0,-1.5,1.4
ENSMUSG00000044206,VSIG4,V-set and immunoglobulin domain containing 4,extracellular vesicular exosome|,negative regulation of interleukin-2 production|negative regulation of T cell proliferation|,None,10,0,0,10,0.3,0.871,0,0,0,0.861,0,0,-1.3,1.6
ENSMUSG00000040569,SLC26A7,"solute carrier family 26, member 7",cytoplasm|endosome|plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|,gastric acid secretion|transport|ion transport|anion transport|anion transport|chloride transport|chloride transport|sulfate transport|inorganic anion transport|bicarbonate transport|oxalate transport|ion transmembrane transport|sulfate transmembrane transport|chloride transmembrane transport|chloride transmembrane transport|,anion channel activity|chloride channel activity|chloride channel activity|bicarbonate transmembrane transporter activity|sulfate transmembrane transporter activity|anion:anion antiporter activity|oxalate transmembrane transporter activity|,10,0,0,10,-0.2,0.237,0,0,0,0.861,0,0,-1.7,1.2
ENSMUSG00000015335,ZDHHC12,"zinc finger, DHHC domain containing 12",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,protein palmitoylation|,"zinc ion binding|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,-0.1,0.164,10,0.2,0.422,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000035582,GDPD4,glycerophosphodiester phosphodiesterase domain containing 4,cellular_component|cytoplasm|membrane|integral component of membrane|,glycerol metabolic process|lipid metabolic process|biological_process|,molecular_function|nuclease activity|phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,1,0.794,10,0,0,0,0,0,0.861,0,0,-0.8,2
ENSMUSG00000032763,ILVBL,ilvB (bacterial acetolactate synthase)-like,membrane|membrane|integral component of membrane|,biological_process|,magnesium ion binding|catalytic activity|transferase activity|thiamine pyrophosphate binding|metal ion binding|,10,0,0,10,-0.2,0.0583,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000007837,PRRG2,proline-rich Gla (G-carboxyglutamic acid) polypeptide 2,extracellular region|membrane|integral component of membrane|,biological_process|,calcium ion binding|protein binding|,10,0,0,10,-0.5,1.45,0,0,0,0.861,0,0,-1.9,0.9
ENSMUSG00000028295,SMIM8,small integral membrane protein 8,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.128,10,0,0,0,0,0,0.861,0,0,-1.7,1.3
ENSMUSG00000024427,SPRY4,sprouty homolog 4 (Drosophila),cytoplasm|Golgi apparatus|membrane|,multicellular organismal development|regulation of signal transduction|negative regulation of MAP kinase activity|,protein binding|,10,0,0,10,0.3,0.538,0,0,0,0.861,0,0,-0.8,1.9
ENSMUSG00000001334,FNDC5,fibronectin type III domain containing 5,extracellular region|peroxisome|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,response to muscle activity|positive regulation of brown fat cell differentiation|,hormone activity|protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000024666,TMEM138,transmembrane protein 138,vacuole|cilium|membrane|integral component of membrane|cell projection|,cell projection organization|cilium assembly|,molecular_function|,10,0,0,10,0.1,0.132,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000049848,CEACAM19,carcinoembryonic antigen-related cell adhesion molecule 19,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000096847,TMEM151B,transmembrane protein 151B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.105,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000021360,GCNT2,"glucosaminyl (N-acetyl) transferase 2, I-branching enzyme",Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|positive regulation of cell proliferation|posttranscriptional regulation of gene expression|posttranscriptional regulation of gene expression|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|negative regulation of cell-substrate adhesion|positive regulation of cell migration|positive regulation of heterotypic cell-cell adhesion|maintenance of lens transparency|positive regulation of protein kinase B signaling|positive regulation of protein kinase B signaling|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|,"N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0,0,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000045498,PCDHB3,protocadherin beta 3,plasma membrane|membrane|integral component of membrane|,cell adhesion|,None,10,0,0,10,-0.5,0.51,0,0,0,0.861,0,0,-2,0.9
ENSMUSG00000043088,IL17RE,interleukin 17 receptor E,extracellular region|cytoplasm|plasma membrane|membrane|integral component of membrane|,inflammatory response|,None,10,0,0,10,0.1,0.0177,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000045005,FZD5,frizzled homolog 5 (Drosophila),cytoplasm|early endosome|Golgi apparatus|plasma membrane|plasma membrane|tight junction|cell surface|membrane|integral component of membrane|cell projection|perinuclear region of cytoplasm|,"embryonic axis specification|angiogenesis|vasculature development|regulation of transcription from RNA polymerase II promoter|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|multicellular organismal development|axonogenesis|brain development|negative regulation of cell proliferation|gonad development|anterior/posterior axis specification, embryo|Wnt signaling pathway|cell differentiation|embryonic camera-type eye development|post-embryonic camera-type eye development|positive regulation of interferon-gamma production|T cell differentiation in thymus|positive regulation of JUN kinase activity|Wnt signaling pathway involved in dorsal/ventral axis specification|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|Spemann organizer formation|canonical Wnt signaling pathway|canonical Wnt signaling pathway|apoptotic process involved in morphogenesis|branching involved in labyrinthine layer morphogenesis|syncytiotrophoblast cell differentiation involved in labyrinthine layer development|labyrinthine layer blood vessel development|chorionic trophoblast cell differentiation|regulation of canonical Wnt signaling pathway|cellular response to molecule of bacterial origin|regulation of chorionic trophoblast cell proliferation|regulation of tight junction assembly|",signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein binding|Wnt-protein binding|Wnt-protein binding|protein kinase binding|PDZ domain binding|ubiquitin protein ligase binding|Wnt-activated receptor activity|,10,0,0,10,0.3,0.905,0,0,0,0.861,0,0,-1.4,1.5
ENSMUSG00000015189,CASD1,CAS1 domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.7,1.3
ENSMUSG00000032657,FAM189B,"family with sequence similarity 189, member B",cellular_component|membrane|integral component of membrane|,biological_process|,WW domain binding|,10,0,0,10,-0.3,0.876,0,0,0,0.861,0,0,-1.7,1.1
ENSMUSG00000041439,MFSD6,major facilitator superfamily domain containing 6,membrane|membrane|integral component of membrane|,immune system process|transmembrane transport|,None,10,0,0,10,0.1,0.134,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000026205,SLC23A3,"solute carrier family 23 (nucleobase transporters), member 3",cellular_component|cytoplasm|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|transporter activity|,10,0.2,0.311,10,0,0,0,0,0,0.861,0,0,-0.7,2
ENSMUSG00000040693,SLCO4C1,"solute carrier organic anion transporter family, member 4C1",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|extracellular vesicular exosome|,transport|ion transport|multicellular organismal development|spermatogenesis|organic anion transport|cell differentiation|ion transmembrane transport|,transporter activity|organic anion transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000032482,CSPG5,chondroitin sulfate proteoglycan 5,endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|Golgi-associated vesicle membrane|,multicellular organismal development|nervous system development|cell differentiation|regulation of growth|regulation of synaptic transmission|,None,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.1,1.9
ENSMUSG00000074037,MC1R,melanocortin 1 receptor,intracellular|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of protein kinase A signaling|sensory perception of pain|positive regulation of cAMP biosynthetic process|negative regulation of tumor necrosis factor production|intracellular signal transduction|melanin biosynthetic process|pigmentation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of protein kinase B signaling|regulation of feeding behavior|UV-damage excision repair|positive regulation of protein kinase C signaling|positive regulation of feeding behavior|,signal transducer activity|G-protein coupled receptor activity|melanocortin receptor activity|melanocortin receptor activity|melanocyte-stimulating hormone receptor activity|melanocyte-stimulating hormone receptor activity|protein binding|ubiquitin protein ligase binding|hormone binding|,10,-0.1,0.0873,10,0,0,0,0,0,0.861,0,0,-1.8,1.2
ENSMUSG00000017057,IL13RA1,"interleukin 13 receptor, alpha 1",membrane|integral component of membrane|,interleukin-13-mediated signaling pathway|,cytokine receptor activity|interleukin-13 receptor activity|,10,0,0,10,0.1,0.0641,0,0,0,0.861,0,0,-1.6,1.3
ENSMUSG00000015396,CD83,CD83 antigen,external side of plasma membrane|membrane|integral component of membrane|,"response to organic cyclic compound|negative regulation of interleukin-4 production|positive regulation of interleukin-10 production|positive regulation of interleukin-2 production|positive regulation of CD4-positive, alpha-beta T cell differentiation|",None,10,-0.1,0.0198,10,0.1,0.0433,0,0,0,0.861,0,0,-1.5,1.4
ENSMUSG00000032394,IGDCC3,"immunoglobulin superfamily, DCC subclass, member 3",cellular_component|membrane|integral component of membrane|,neuromuscular process controlling balance|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000020099,UNC5B,unc-5 homolog B (C. elegans),membrane|integral component of membrane|membrane raft|,apoptotic process|signal transduction|multicellular organismal development|axon guidance|positive regulation of phosphatidylinositol 3-kinase signaling|anterior/posterior axon guidance|netrin-activated signaling pathway|negative regulation of neuron apoptotic process|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|,netrin receptor activity|protein binding|,10,0,0,10,0.1,0.0687,0,0,0,0.861,0,0,-0.7,2
ENSMUSG00000029571,TMEM106B,transmembrane protein 106B,lysosome|lysosomal membrane|endosome|membrane|integral component of membrane|extracellular vesicular exosome|,transport|lysosome localization|dendrite morphogenesis|,molecular_function|,10,0,0,10,-0.2,0.647,0,0,0,0.861,0,0,-1.7,1.2
ENSMUSG00000034918,CDHR2,cadherin-related family member 2,membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|negative regulation of cell growth|,molecular_function|,10,-0.2,0.659,10,0.3,0.489,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000042195,SLC35F2,"solute carrier family 35, member F2",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0,0,10,0.2,0.497,0,0,0,0.861,0,0,-1,1.9
ENSMUSG00000095115,ITPRIPL2,"inositol 1,4,5-triphosphate receptor interacting protein-like 2",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.123,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000013091,TMEM190,transmembrane protein 190,inner acrosomal membrane|nucleus|membrane|integral component of membrane|,hematopoietic progenitor cell differentiation|,protein self-association|,10,0,0,10,0.1,0.115,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000033350,CHST2,carbohydrate sulfotransferase 2,Golgi membrane|Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|,carbohydrate metabolic process|N-acetylglucosamine metabolic process|N-acetylglucosamine metabolic process|sulfur compound metabolic process|inflammatory response|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,-0.1,0.26,10,0.2,0.658,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000037995,IGSF9,"immunoglobulin superfamily, member 9",plasma membrane|membrane|integral component of membrane|cell junction|axon|dendrite|synapse|inhibitory synapse|,homophilic cell adhesion|multicellular organismal development|nervous system development|dendrite development|cell differentiation|regulation of synapse organization|,protein binding involved in cell-cell adhesion|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.3
ENSMUSG00000024187,ITFG3,integrin alpha FG-GAP repeat containing 3,cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.1,1.9
ENSMUSG00000045679,PQLC3,PQ loop repeat containing,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.403,0,0,0,0.861,0,0,-1.7,1.6
ENSMUSG00000018865,SULT4A1,"sulfotransferase family 4A, member 1",cytoplasm|cytoplasm|,lipid metabolic process|sulfur compound metabolic process|steroid metabolic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0,0,10,0,0,0,0,0,0.861,0,0,-1,2
ENSMUSG00000043843,TMEM145,transmembrane protein 145,cellular_component|membrane|integral component of membrane|,G-protein coupled receptor signaling pathway|biological_process|response to pheromone|,molecular_function|,10,-0.2,0.327,10,0,0,0,0,0,0.861,0,0,-1.7,1.2
ENSMUSG00000036256,IGFBP7,insulin-like growth factor binding protein 7,extracellular region|extracellular space|extracellular matrix|extracellular vesicular exosome|,regulation of cell growth|cell adhesion|inner ear development|regulation of steroid biosynthetic process|,insulin-like growth factor binding|growth factor binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.8,1.1
ENSMUSG00000048772,TMEM53,transmembrane protein 53,nucleus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.0602,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000048661,LEMD3,LEM domain containing 3,nucleus|nuclear envelope|nuclear inner membrane|integral component of nuclear inner membrane|membrane|integral component of membrane|,negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of BMP signaling pathway|negative regulation of activin receptor signaling pathway|skeletal muscle cell differentiation|regulation of cell cycle|,nucleotide binding|DNA binding|,10,0.1,0.311,10,0,0,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000039178,TBC1D19,"TBC1 domain family, member 19",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000023074,MOSPD1,motile sperm domain containing 1,membrane|integral component of membrane|,None,molecular_function|structural molecule activity|,9,0,0,10,0.3,0.0894,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000028459,CD72,CD72 antigen,integral component of plasma membrane|membrane|integral component of membrane|,None,carbohydrate binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1,1.9
ENSMUSG00000037553,ZDHHC18,"zinc finger, DHHC domain containing 18",Golgi apparatus|membrane|integral component of membrane|,protein palmitoylation|cellular protein localization|,"zinc ion binding|palmitoyltransferase activity|palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,0,0,10,0,0,0,0,0,0.861,0,0,-1,1.9
ENSMUSG00000048796,CYB561D1,cytochrome b-561 domain containing 1,cellular_component|membrane|integral component of membrane|,transport|biological_process|oxidation-reduction process|,molecular_function|metal ion binding|,10,0.1,0.176,9,0,0,0,0,0,0.861,0,0,-1.8,1.3
ENSMUSG00000069441,DSG1A,desmoglein 1 alpha,plasma membrane|cell-cell junction|cytoplasmic side of plasma membrane|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|cell junction|desmosome|desmosome|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|,calcium ion binding|protein binding|gamma-catenin binding|metal ion binding|,10,0.2,0.264,10,0,0,0,0,0,0.861,0,0,-1.2,1.7
ENSMUSG00000090958,LRRC32,leucine rich repeat containing 32,None,positive regulation of gene expression|negative regulation of activated T cell proliferation|negative regulation of cytokine secretion|,None,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.3,1.7
ENSMUSG00000000915,HIP1R,huntingtin interacting protein 1 related,cytoplasm|cytoskeleton|coated pit|membrane|clathrin-coated vesicle|cytoplasmic vesicle|intracellular membrane-bounded organelle|,endocytosis|receptor-mediated endocytosis|receptor-mediated endocytosis|,actin binding|protein binding|phospholipid binding|phosphatidylinositol binding|,10,0,0,10,0.1,0.0807,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000030089,SLC41A3,"solute carrier family 41, member 3",plasma membrane|membrane|integral component of membrane|,cation transport|biological_process|,protein binding|cation transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.7,1.3
ENSMUSG00000096364,GPR45,G protein-coupled receptor 45,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.2,0.567,10,0,0,0,0,0,0.861,0,0,-1.7,1.2
ENSMUSG00000050666,VSTM4,V-set and transmembrane domain containing 4,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0572,10,-0.7,0.797,0,0,0,0.861,0,0,-1.8,1.2
ENSMUSG00000025946,PTH2R,parathyroid hormone 2 receptor,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|parathyroid hormone receptor activity|,10,-0.1,0.099,10,0.1,0.24,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000020393,KREMEN1,kringle containing transmembrane protein 1,membrane|integral component of membrane|,Wnt signaling pathway|,None,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000038059,SMIM3,small integral membrane protein 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,0.165,10,-0.1,0.656,0,0,0,0.861,0,0,-0.9,2
ENSMUSG00000029735,TPK1,thiamine pyrophosphokinase,None,thiamine metabolic process|thiamine diphosphate biosynthetic process|phosphorylation|,nucleotide binding|thiamine diphosphokinase activity|ATP binding|kinase activity|transferase activity|thiamine binding|,9,0,0,7,0.4,0.918,0,0,0,0.861,0,0,-1.1,2
ENSMUSG00000040856,DLK1,delta-like 1 homolog (Drosophila),external side of plasma membrane|membrane|integral component of membrane|,embryo development|post-embryonic development|regulation of gene expression|cell differentiation|negative regulation of Notch signaling pathway|embryonic skeletal system development|,calcium ion binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.5
ENSMUSG00000020439,SMTN,smoothelin,nucleus|cytoplasm|cytoskeleton|actin cytoskeleton|,None,None,10,-0.1,0.0134,10,0.5,1.64,0,0,0,0.861,0,0,-0.9,1.9
ENSMUSG00000058396,GPR182,G protein-coupled receptor 182,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,adrenomedullin receptor activity|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,-0.1,0.233,0,0,0,0.861,0,0,-1.6,1.4
ENSMUSG00000026463,ATP2B4,"ATPase, Ca++ transporting, plasma membrane 4",plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|basolateral plasma membrane|neuron projection|protein complex|sperm principal piece|,ATP catabolic process|calcium ion transport|calcium ion transport|calcium ion transmembrane transport|calcium ion export|negative regulation of peptidyl-cysteine S-nitrosylation|regulation of sodium ion transmembrane transport|,nucleotide binding|calcium-transporting ATPase activity|ATP binding|hydrolase activity|sodium channel regulator activity|PDZ domain binding|scaffold protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.2,1.8
ENSMUSG00000047085,LRRC4B,leucine rich repeat containing 4B,plasma membrane|membrane|integral component of membrane|cell junction|cerebellar mossy fiber|synapse|,positive regulation of synapse assembly|,receptor binding|protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-2,0.9
ENSMUSG00000028825,RHD,"Rh blood group, D antigen",membrane|integral component of membrane|,ammonium transport|erythrocyte development|multicellular organismal iron ion homeostasis|,molecular_function|ammonium transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.6,1.5
ENSMUSG00000032595,CDHR4,cadherin-related family member 4,cellular_component|membrane|integral component of membrane|,cell adhesion|biological_process|,molecular_function|,10,0,0,10,0.9,0.337,0,0,0,0.861,0,0,-0.8,2
ENSMUSG00000021678,F2RL1,coagulation factor II (thrombin) receptor-like 1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|pseudopodium|,"T cell activation involved in immune response|immune system process|positive regulation of leukocyte chemotaxis|positive regulation of cytokine secretion involved in immune response|positive regulation of glomerular filtration|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration|blood coagulation|negative regulation of tumor necrosis factor-mediated signaling pathway|positive regulation of phosphatidylinositol 3-kinase signaling|regulation of blood coagulation|positive regulation of cell migration|positive regulation of actin filament depolymerization|positive regulation of pseudopodium assembly|positive regulation of superoxide anion generation|positive regulation of toll-like receptor 2 signaling pathway|negative regulation of toll-like receptor 3 signaling pathway|positive regulation of toll-like receptor 3 signaling pathway|positive regulation of toll-like receptor 4 signaling pathway|positive regulation of Rho protein signal transduction|positive regulation of Rho protein signal transduction|chemokine (C-C motif) ligand 2 secretion|neutrophil activation|regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of eosinophil degranulation|innate immune response|positive regulation of vasodilation|positive regulation of vasodilation|positive regulation of vasodilation|positive regulation of transcription from RNA polymerase II promoter|regulation of JNK cascade|negative regulation of JNK cascade|positive regulation of JNK cascade|interleukin-1 beta secretion|leukocyte migration|positive regulation of chemotaxis|positive regulation of positive chemotaxis|defense response to virus|defense response to virus|positive regulation of phagocytosis, engulfment|establishment of endothelial barrier|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|thrombin receptor signaling pathway|leukocyte proliferation|positive regulation of neutrophil mediated killing of gram-negative bacterium|interleukin-10 secretion|interferon-gamma secretion|chemokine secretion|chemokine secretion|negative regulation of chemokine secretion|mature dendritic cell differentiation|mature dendritic cell differentiation|positive regulation of renin secretion into blood stream|positive regulation of interleukin-8 secretion|positive regulation of interleukin-6 secretion|",G-protein alpha-subunit binding|signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|thrombin receptor activity|G-protein beta-subunit binding|heterotrimeric G-protein binding|,10,0.1,0.0345,10,0,0,0,0,0,0.861,0,0,-1.4,1.5
ENSMUSG00000036565,TTYH3,tweety homolog 3 (Drosophila),plasma membrane|membrane|integral component of membrane|chloride channel complex|extracellular vesicular exosome|,transport|ion transport|chloride transport|chloride transmembrane transport|,intracellular calcium activated chloride channel activity|chloride channel activity|,10,-0.1,0.0391,10,0.1,0.369,0,0,0,0.861,0,0,-1.4,1.6
ENSMUSG00000069237,C78339,expressed sequence C78339,cellular_component|,biological_process|,molecular_function|,10,0.3,0.718,10,-0.2,0.014,0,0,0,0.861,0,0,-1.3,1.6
ENSMUSG00000037762,SLC16A9,"solute carrier family 16 (monocarboxylic acid transporters), member 9",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|urate metabolic process|transmembrane transport|,molecular_function|symporter activity|,10,0,0,10,-0.1,0.194,0,0,0,0.861,0,0,-1.7,1.3
ENSMUSG00000030114,KLRG1,"killer cell lectin-like receptor subfamily G, member 1",plasma membrane|membrane|integral component of membrane|,immune system process|cell surface receptor signaling pathway|innate immune response|,carbohydrate binding|carbohydrate binding|,10,0,0,10,-1.1,0.676,0,0,0,0.861,0,0,-2,0.6
ENSMUSG00000043252,TMEM64,transmembrane protein 64,endoplasmic reticulum|membrane|integral component of membrane|,regulation of ATPase activity|positive regulation of osteoclast differentiation|positive regulation of bone resorption|cytosolic calcium ion homeostasis|,protein binding|,10,-0.2,0.517,10,0,0,0,0,0,0.861,0,0,-1.8,1.1
ENSMUSG00000035498,CDCP1,CUB domain containing protein 1,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.492,0,0,0,0.861,0,0,-1.3,1.6
ENSMUSG00000079260,TMPPE,transmembrane protein with metallophosphoesterase domain,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.8,1.41,0,0,0,0.861,0,0,-2,0.8
ENSMUSG00000015094,NPDC1,"neural proliferation, differentiation and control 1",membrane|integral component of membrane|,None,None,10,0.3,0.995,10,0,0,0,0,0,0.861,0,0,-1.4,1.5
ENSMUSG00000038390,GPR162,G protein-coupled receptor 162,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,-0.1,0.0824,0,0,0,0.861,0,0,-1.2,1.7
ENSMUSG00000018820,ZFYVE27,"zinc finger, FYVE domain containing 27",cytoplasm|endosome|endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|axon|dendrite|growth cone membrane|growth cone membrane|cell projection|recycling endosome membrane|,neuron projection development|neurotrophin TRK receptor signaling pathway|protein localization to plasma membrane|,metal ion binding|,10,0,0,10,-0.1,0.191,0,0,0,0.861,0,0,-1.6,1.3
ENSMUSG00000029149,KRTCAP3,keratinocyte associated protein 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.388,10,0,0,0,0,0,0.861,0,0,-1.5,1.5
ENSMUSG00000041779,TRAM2,translocating chain-associating membrane protein 2,cellular_component|membrane|integral component of membrane|,transport|protein transport|collagen biosynthetic process|,protein binding|,10,0,0,10,0,0,0,0,0,0.861,0,0,-1.4,1.7
ENSMUSG00000027956,TMEM144,transmembrane protein 144,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.6,1.15,0,0,0,0.861,0,0,-0.9,2
ENSMUSG00000035914,CD276,CD276 antigen,external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,positive regulation of bone mineralization|positive regulation of T cell proliferation|positive regulation of T cell proliferation|T cell activation|negative regulation of T cell proliferation|negative regulation of T cell proliferation|negative regulation of interferon-gamma biosynthetic process|negative regulation of interferon-gamma biosynthetic process|positive regulation of interferon-gamma biosynthetic process|negative regulation of interleukin-2 biosynthetic process|positive regulation of osteoblast differentiation|negative regulation of inflammatory response|regulation of immune response|positive regulation of interleukin-2 secretion|,receptor binding|receptor binding|,10,0,0,10,-0.2,0.203,0,0,0,0.861,0,0,-1.9,1
ENSMUSG00000037257,AAGAB,alpha- and gamma-adaptin binding protein,nucleus|cytoplasm|,transport|biological_process|protein transport|,molecular_function|,10,1.8,73.5,10,1.5,26.8,1.7,98.7,98.7,1.00E-05,1,1,1.2,2.2
ENSMUSG00000030060,HMCES,"5-hydroxymethylcytosine (hmC) binding, ES cell specific",cellular_component|,proteolysis|biological_process|,molecular_function|DNA binding|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,1.7,43.3,10,1.1,12.3,1.6,54.7,54.7,1.00E-05,1,1,1.1,2.3
ENSMUSG00000006307,KMT2B,lysine (K)-specific methyltransferase 2B,nucleus|histone methyltransferase complex|,"ovarian follicle development|transcription, DNA-templated|regulation of transcription, DNA-templated|oocyte differentiation|gene silencing|chromatin modification|peptidyl-lysine methylation|ovulation|methylation|histone lysine methylation|histone H3-K4 methylation|regulation of histone H3-K4 methylation|histone H3-K4 trimethylation|",DNA binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H3-K4 specific)|metal ion binding|,10,1.8,41.5,10,0.8,9.22,1.2,48.6,48.6,2.00E-05,1,1,0.8,2.2
ENSMUSG00000031864,INTS10,integrator complex subunit 10,nucleus|integrator complex|,snRNA processing|,molecular_function|,10,1.3,28.5,10,1,10.9,1.2,37.5,37.5,4.00E-05,1,1,0.9,1.8
ENSMUSG00000010277,2610507B11RIK,RIKEN cDNA 2610507B11 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-1.4,30.2,10,-0.6,6.89,-1,35.2,-35.2,5.00E-05,1,1,-1.7,-0.4
ENSMUSG00000057572,ZBTB8OS,zinc finger and BTB domain containing 8 opposite strand,extracellular vesicular exosome|,biological_process|,molecular_function|,8,1.4,17.8,6,1.6,14.7,1.5,32.1,32.1,9.00E-05,1,1,0.8,2.3
ENSMUSG00000042660,WDR55,WD repeat domain 55,nucleus|nucleolus|cytoplasm|,rRNA processing|,molecular_function|,8,1.7,28.6,8,0.8,5.19,0.9,31.2,31.2,0.00011,1,1,0.5,2.4
ENSMUSG00000074576,MOCS3,molybdenum cofactor synthesis 3,cytoplasm|cytosol|cytosol|,tRNA wobble uridine modification|tRNA wobble position uridine thiolation|Mo-molybdopterin cofactor biosynthetic process|tRNA processing|metabolic process|protein adenylylation|enzyme active site formation via L-cysteine persulfide|protein urmylation|tRNA thio-modification|,nucleotide binding|catalytic activity|thiosulfate sulfurtransferase activity|thiosulfate sulfurtransferase activity|ATP binding|transferase activity|nucleotidyltransferase activity|sulfurtransferase activity|URM1 activating enzyme activity|URM1 activating enzyme activity|metal ion binding|molybdopterin-synthase sulfurtransferase activity|molybdopterin-synthase adenylyltransferase activity|protein adenylyltransferase activity|,9,0.7,20.5,9,1.1,10.9,0.9,30.1,30.1,0.00012,1,1,0.6,1.5
ENSMUSG00000025133,INTS4,integrator complex subunit 4,nucleus|integrator complex|,snRNA processing|,molecular_function|,10,2,29.9,9,0.4,1.07,1.9,27.3,27.3,0.00027,1,1,0.6,3.4
ENSMUSG00000034263,VWA9,von Willebrand factor A domain containing 9,None,biological_process|,molecular_function|,10,1.3,22,10,2.1,4.15,1.4,25.1,25.1,0.00063,0,1,0.7,2.3
ENSMUSG00000025862,STAG2,stromal antigen 2,"chromosome, centromeric region|chromatin|chromatin|nucleus|chromosome|nucleolus|plasma membrane|actin cytoskeleton|membrane|intermediate filament cytoskeleton|",cell cycle|chromosome segregation|sister chromatid cohesion|mitotic nuclear division|meiotic nuclear division|stem cell maintenance|negative regulation of DNA endoreduplication|cell division|,chromatin binding|,10,0.7,14.1,10,0.9,11.3,0.8,24.5,24.5,0.00079,0,1,0.5,1.1
ENSMUSG00000014418,HPS5,Hermansky-Pudlak syndrome 5 homolog (human),cytoplasm|BLOC-2 complex|,organelle organization|blood coagulation|pigmentation|,protein binding|,10,0.7,10.1,10,0.8,14.1,0.7,23.7,23.7,0.00115,0,1,0.5,1.2
ENSMUSG00000037466,4930427A07RIK,RIKEN cDNA 4930427A07 gene,cellular_component|,biological_process|,molecular_function|,8,0.9,5.95,8,1.7,20.5,1.6,23.6,23.6,0.00118,0,1,0.8,2.6
ENSMUSG00000024118,1600002H07RIK,RIKEN cDNA 1600002H07 gene,cellular_component|,biological_process|,molecular_function|,10,1.1,11.7,10,1.1,12.3,1.1,23.6,23.6,0.00118,0,1,0.6,2
ENSMUSG00000024170,TELO2,"TEL2, telomere maintenance 2, homolog (S. cerevisiae)","chromosome, telomeric region|intracellular|nucleus|chromosome|cytoplasm|membrane|TORC1 complex|TORC2 complex|",regulation of TOR signaling|,protein complex binding|protein complex binding|protein complex scaffold|,10,1,9.29,10,1,14.1,1,23,23,0.00152,0,0,0.5,1.6
ENSMUSG00000059474,MBTD1,mbt domain containing 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|embryonic skeletal system development|",molecular_function|zinc ion binding|metal ion binding|,10,1.1,0.764,10,-1.4,22.9,-1.3,22.4,-22.4,0.00184,0,0,-2.4,-0.8
ENSMUSG00000029463,FAM216A,"family with sequence similarity 216, member A",cellular_component|,biological_process|,molecular_function|,10,-1.7,22.8,10,-1,0.0285,-1.7,21.6,-21.6,0.0025,0,0,-3,-1.1
ENSMUSG00000046295,ANKLE1,ankyrin repeat and LEM domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-1.4,24.3,9,0.3,0.615,-1.4,21.3,-21.3,0.00276,0,0,-2.8,-0.4
ENSMUSG00000037049,SMPD1,"sphingomyelin phosphodiesterase 1, acid lysosomal",extracellular space|lysosome|lamellar body|extracellular vesicular exosome|,sphingomyelin catabolic process|metabolic process|termination of signal transduction|positive regulation of protein dephosphorylation|response to cocaine|positive regulation of apoptotic process|negative regulation of MAP kinase activity|ceramide biosynthetic process|,"sphingomyelin phosphodiesterase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,1.1,13.3,10,0.8,8.72,0.8,20.9,20.9,0.00326,0,0,0.5,1.4
ENSMUSG00000003208,CCDC94,coiled-coil domain containing 94,cellular_component|,biological_process|,molecular_function|,9,-1.3,23.4,9,0.5,0.599,-1.3,20.4,-20.4,0.00386,0,0,-2,-0.9
ENSMUSG00000021036,SPTLC2,"serine palmitoyltransferase, long chain base subunit 2",mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|serine C-palmitoyltransferase complex|serine C-palmitoyltransferase complex|,lipid metabolic process|sphingolipid metabolic process|sphingomyelin biosynthetic process|metabolic process|biosynthetic process|sphinganine biosynthetic process|sphingosine biosynthetic process|ceramide biosynthetic process|,"catalytic activity|serine C-palmitoyltransferase activity|serine C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|pyridoxal phosphate binding|",10,1.2,7.73,10,1.2,13,1.2,20.3,20.3,0.00398,0,0,0.6,1.9
ENSMUSG00000040247,TBC1D10C,"TBC1 domain family, member 10c",membrane|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,9,-0.3,2.72,10,-1.8,22.6,-1.8,20.3,-20.3,0.00398,0,0,-3,-0.7
ENSMUSG00000040345,ARHGAP9,Rho GTPase activating protein 9,cellular_component|,positive regulation of GTPase activity|,"GTPase activator activity|phosphatidylinositol-3,4,5-trisphosphate binding|",10,-1.5,22.7,10,-0.4,0.844,-1.4,20.2,-20.2,0.00419,0,0,-3,-0.5
ENSMUSG00000022978,MIS18A,MIS18 kinetochore protein homolog A (S. pombe),"chromosome, centromeric region|nucleus|chromosome|cytoplasm|",cell cycle|chromosome segregation|mitotic nuclear division|centromere-specific nucleosome assembly|regulation of DNA methylation|cell division|,protein binding|,7,1.2,11.7,7,1,8.96,1.1,20,20,0.00467,0,0,0.8,1.9
ENSMUSG00000022466,RPAP3,RNA polymerase II associated protein 3,cellular_component|,biological_process|,molecular_function|,8,0.9,7.95,9,1.2,12.6,1,19.8,19.8,0.0052,0,0,0.7,1.7
ENSMUSG00000007656,ARPP19,cAMP-regulated phosphoprotein 19,cellular_component|cytoplasm|,G2/M transition of mitotic cell cycle|cell cycle|mitotic nuclear division|positive regulation of gluconeogenesis|positive regulation of Ras protein signal transduction|cell division|,protein phosphatase inhibitor activity|receptor binding|potassium channel regulator activity|,9,1,13.1,9,0.9,7.1,0.9,19.8,19.8,0.0052,0,0,0.6,1.4
ENSMUSG00000032637,ATXN2L,ataxin 2-like,cytoplasm|cytoplasmic stress granule|membrane|nuclear speck|,regulation of cytoplasmic mRNA processing body assembly|stress granule assembly|,poly(A) RNA binding|,9,0.8,5.39,10,1.2,15.3,1,19.6,19.6,0.00578,0,0,0.6,1.8
ENSMUSG00000075054,YAE1D1,Yae1 domain containing 1,cellular_component|,biological_process|,molecular_function|,9,1.3,10.9,10,1.8,9.08,1.3,18.7,18.7,0.00824,0,0,0.9,2.6
ENSMUSG00000023764,SFI1,"Sfi1 homolog, spindle assembly associated (yeast)",cytoplasm|cytoskeleton|,negative regulation of phosphatase activity|,phosphatase binding|,6,0.7,14.9,6,0.9,3.89,0.7,18.3,18.3,0.00896,0,0,0.4,1.4
ENSMUSG00000025591,TMA16,translation machinery associated 16 homolog (S. cerevisiae),nucleus|,biological_process|,molecular_function|,9,1.1,10,9,1.8,8.53,1.1,17.7,17.7,0.00972,0,0,0.6,2.4
ENSMUSG00000030680,PAGR1A,PAXIP1 associated glutamate rich protein 1A,nucleus|histone methyltransferase complex|histone methyltransferase complex|,histone H3-K27 demethylation|,protein binding|,10,0.7,15.4,10,0.4,3.05,0.7,17.5,17.5,0.00998,0,0,0.4,1.1
ENSMUSG00000020929,EFTUD2,elongation factor Tu GTP binding domain containing 2,nucleus|nucleus|spliceosomal complex|cytoplasm|Cajal body|membrane|nuclear speck|catalytic step 2 spliceosome|,mRNA processing|translation|translational elongation|RNA splicing|,nucleotide binding|translation elongation factor activity|GTPase activity|protein binding|GTP binding|poly(A) RNA binding|,8,1,6.39,9,1.3,11.9,1,17,17,0.0104,0,0,0.6,2
ENSMUSG00000024095,HNRNPLL,heterogeneous nuclear ribonucleoprotein L-like,nucleus|membrane|ribonucleoprotein complex|,mRNA processing|positive regulation of RNA splicing|,nucleotide binding|nucleic acid binding|RNA binding|mRNA binding|poly(A) RNA binding|,10,0.8,13.2,10,0.6,3.6,0.7,16.4,16.4,0.0105,0,0,0.4,1.5
ENSMUSG00000031792,USB1,U6 snRNA biogenesis 1,nucleus|,"mRNA processing|RNA splicing|U6 snRNA 3'-end processing|RNA phosphodiester bond hydrolysis, exonucleolytic|","3'-5'-exoribonuclease activity|catalytic activity|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|photoreceptor cyclic-nucleotide phosphodiesterase activity|nuclease activity|hydrolase activity|7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity|inositol phosphosphingolipid phospholipase activity|inositol phosphorylceramide phospholipase activity|mannosyl-inositol phosphorylceramide phospholipase activity|mannosyl-diinositol phosphorylceramide phospholipase activity|",10,0.5,11.3,10,0.5,5.27,0.5,16.2,16.2,0.0105,0,0,0.3,0.9
ENSMUSG00000048170,MCMBP,MCM (minichromosome maintenance deficient) binding protein,nucleus|cytoplasm|plasma membrane|MCM complex|,mitotic S phase|DNA replication|DNA-dependent DNA replication|cell cycle|sister chromatid cohesion|mitotic nuclear division|cell division|,chromatin binding|,9,0.7,2.98,9,1,14.3,1,16.2,16.2,0.0105,0,0,0.5,1.6
ENSMUSG00000022961,SON,Son DNA binding protein,nucleus|nuclear speck|,"microtubule cytoskeleton organization|cytokinesis|transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|cell cycle|RNA splicing|negative regulation of apoptotic process|regulation of RNA splicing|regulation of cell cycle|",nucleic acid binding|DNA binding|RNA binding|protein binding|poly(A) RNA binding|RS domain binding|,10,0.7,10.4,8,1.1,6.49,0.8,16.1,16.1,0.0105,0,0,0.4,1.4
ENSMUSG00000026975,DPH7,diphthamine biosynethesis 7,cellular_component|,peptidyl-diphthamide biosynthetic process from peptidyl-histidine|,molecular_function|,10,0.7,10.5,10,0.5,4.99,0.6,14.8,14.8,0.0109,0,0,0.3,1
ENSMUSG00000022253,NADK2,"NAD kinase 2, mitochondrial",mitochondrion|mitochondrion|,NADP biosynthetic process|metabolic process|phosphorylation|NAD metabolic process|,nucleotide binding|NAD+ kinase activity|ATP binding|kinase activity|transferase activity|protein homodimerization activity|,9,0.6,10.2,9,0.6,4.9,0.6,14.7,14.7,0.0109,0,0,0.3,1.4
ENSMUSG00000000561,WDR77,WD repeat domain 77,nucleus|cytoplasm|Golgi apparatus|cytosol|methylosome|,regulation of transcription from RNA polymerase II promoter|positive regulation of cell proliferation|negative regulation of cell proliferation|secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development|negative regulation of epithelial cell proliferation involved in prostate gland development|regulation of RNA biosynthetic process|,protein binding|ligand-dependent nuclear receptor transcription coactivator activity|,10,1.1,5.54,10,-1,9.33,-0.9,13.4,-13.4,0.0115,0,0,-1.7,-0.4
ENSMUSG00000053453,THOC7,THO complex 7 homolog (Drosophila),transcription export complex|THO complex|THO complex part of transcription export complex|nucleus|cytoplasm|,mRNA processing|mRNA export from nucleus|transport|RNA splicing|viral mRNA export from host cell nucleus|mRNA transport|,RNA binding|protein binding|,10,0.7,11.2,10,-1.2,6.03,0.7,12.6,12.6,0.0123,0,0,0.4,1.5
ENSMUSG00000014601,STRIP1,striatin interacting protein 1,nucleus|cytoplasm|extracellular vesicular exosome|,regulation of cell morphogenesis|cortical actin cytoskeleton organization|,molecular_function|,10,0.6,9.16,10,2,5.78,0.7,12.5,12.5,0.0124,0,0,0.3,2
ENSMUSG00000020684,RASL10B,"RAS-like, family 10, member B",cellular_component|plasma membrane|membrane|,regulation of systemic arterial blood pressure by atrial natriuretic peptide|GTP catabolic process|signal transduction|small GTPase mediated signal transduction|positive regulation of peptide hormone secretion|,nucleotide binding|protein binding|GTP binding|,10,-1.3,15.6,10,0.2,0.588,-1.3,12.4,-12.4,0.0125,0,0,-2,-0.3
ENSMUSG00000068479,MFAP1A,microfibrillar-associated protein 1A,microfibril|,biological_process|,poly(A) RNA binding|,9,1.4,12,9,-0.8,10.3,1.3,11.1,11.1,0.0141,0,0,-0.9,3
ENSMUSG00000038145,SNRK,SNF related kinase,nucleus|,protein phosphorylation|phosphorylation|,"nucleotide binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-1,10.3,10,-0.4,1.64,-0.9,11,-11,0.0143,0,0,-1.7,-0.4
ENSMUSG00000027469,TPX2,"TPX2, microtubule-associated protein homolog (Xenopus laevis)",spindle pole|nucleus|cytoplasm|aster|spindle|cytoskeleton|microtubule|spindle microtubule|microtubule cytoskeleton|axon hillock|,apoptotic process|cell cycle|mitotic nuclear division|activation of protein kinase activity|spindle assembly|cell division|regulation of mitotic spindle organization|,protein binding|protein kinase binding|protein kinase binding|,10,0.7,4.22,10,1.4,7.96,0.9,10.8,10.8,0.0146,0,0,0.5,2.2
ENSMUSG00000028066,PMF1,polyamine-modulated factor 1,"MIS12/MIND type complex|chromosome, centromeric region|kinetochore|nucleus|chromosome|","transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|chromosome segregation|mitotic nuclear division|cell division|regulation of RNA biosynthetic process|",transcription coactivator activity|transcription coactivator activity|protein binding|leucine zipper domain binding|,9,1.2,13.2,9,-0.8,10.3,1.1,10.7,10.7,0.0148,0,0,-1,2
ENSMUSG00000079710,GM3448,predicted gene 3448,cellular_component|,biological_process|,molecular_function|,10,0.2,0.346,10,1.5,13.7,1.5,10.7,10.7,0.0148,0,0,0.4,2.7
ENSMUSG00000015605,SRF,serum response factor,nuclear chromatin|nucleus|nucleus|nucleus|cytoplasm|,"patterning of blood vessels|in utero embryonic development|mesoderm formation|neuron migration|trophectodermal cell differentiation|heart looping|morphogenesis of an epithelial sheet|cell migration involved in sprouting angiogenesis|cell migration involved in sprouting angiogenesis|leukocyte differentiation|positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|actin filament organization|cell-matrix adhesion|multicellular organismal development|gastrulation|heart development|long-term memory|negative regulation of cell proliferation|associative learning|response to hormone|epithelial structure maintenance|positive regulation of transcription via serum response element binding|single organismal cell-cell adhesion|hippocampus development|tangential migration from the subventricular zone to the olfactory bulb|actin cytoskeleton organization|contractile actin filament bundle assembly|regulation of cell adhesion|platelet activation|platelet formation|negative regulation of cell migration|neuron projection development|regulation of water loss via skin|response to cytokine|megakaryocyte development|dorsal aorta morphogenesis|mRNA transcription from RNA polymerase II promoter|stress fiber assembly|skin morphogenesis|positive thymic T cell selection|sarcomere organization|positive regulation of cell differentiation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle contraction|positive regulation of transcription by glucose|muscle cell cellular homeostasis|developmental growth|erythrocyte development|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of filopodium assembly|cardiac myofibril assembly|hematopoietic stem cell differentiation|positive regulation of transcription initiation from RNA polymerase II promoter|long term synaptic depression|heart trabecula formation|cardiac vascular smooth muscle cell differentiation|eyelid development in camera-type eye|tight junction assembly|primitive streak formation|epithelial cell-cell adhesion|cellular senescence|negative regulation of beta-amyloid clearance|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|RNA polymerase II transcription factor binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|serum response element binding|serum response element binding|chromatin DNA binding|protein homodimerization activity|sequence-specific DNA binding|protein dimerization activity|,10,0.9,4.98,10,0.9,6.02,0.9,10.6,10.6,0.0149,0,0,0.5,1.8
ENSMUSG00000009549,SRP14,signal recognition particle 14,"nucleus|nucleolus|cytoplasm|signal recognition particle, endoplasmic reticulum targeting|ribonucleoprotein complex|intercellular bridge|signal recognition particle|extracellular vesicular exosome|",SRP-dependent cotranslational protein targeting to membrane|response to drug|protein targeting to ER|,RNA binding|7S RNA binding|endoplasmic reticulum signal peptide binding|poly(A) RNA binding|,7,1.1,7.18,7,-1,5.07,-1.1,10.5,-10.5,0.0151,0,0,-2,1.6
ENSMUSG00000022463,SREBF2,sterol regulatory element binding factor 2,nucleus|nucleus|nucleolus|cytoplasm|cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|dendrite|cytoplasmic vesicle|SREBP-SCAP-Insig complex|intracellular membrane-bounded organelle|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|lipid metabolic process|steroid metabolic process|cholesterol metabolic process|response to hormone|positive regulation of cholesterol storage|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cholesterol efflux|regulation of cholesterol homeostasis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|protein C-terminus binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein dimerization activity|E-box binding|,10,0.7,1.05,10,1.1,10.2,0.6,10.4,10.4,0.0153,0,0,0.3,1.7
ENSMUSG00000020059,SYCP3,synaptonemal complex protein 3,condensed chromosome|condensed nuclear chromosome|synaptonemal complex|lateral element|transverse filament|male germ cell nucleus|nucleus|nucleus|chromosome|,"meiotic DNA repair synthesis|cell cycle|female meiosis sister chromatid cohesion|mitotic nuclear division|meiotic nuclear division|synapsis|synaptonemal complex assembly|synaptonemal complex assembly|spermatogenesis|spermatogenesis|photosynthesis|female meiosis chromosome segregation|sperm chromatin condensation|spermatogenesis, exchange of chromosomal proteins|negative regulation of apoptotic process|chiasma assembly|chiasma assembly|cell division|female meiosis chromosome separation|lateral element assembly|",DNA binding|protein binding|protein heterodimerization activity|,10,0.2,0.713,10,-1.5,13.4,-1.5,10,-10,0.0159,0,0,-2.9,-0.3
ENSMUSG00000030224,STRAP,serine/threonine kinase receptor associated protein,nucleus|cytoplasm|cytosol|plasma membrane|cell junction|SMN complex|SMN-Sm protein complex|,negative regulation of transcription from RNA polymerase II promoter|spliceosomal snRNP assembly|mRNA processing|RNA splicing|negative regulation of epithelial cell migration|negative regulation of epithelial to mesenchymal transition|phosphorylation|maintenance of gastrointestinal epithelium|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of epithelial cell proliferation|negative regulation of pathway-restricted SMAD protein phosphorylation|,receptor binding|protein binding|kinase activity|transferase activity|poly(A) RNA binding|,8,1.5,7.99,7,1.5,2.19,1.5,9.85,9.85,0.0162,0,0,0.6,2.8
ENSMUSG00000030527,CRTC3,CREB regulated transcription coactivator 3,nucleus|nucleus|cytoplasm|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of CREB transcription factor activity|negative regulation of cAMP-mediated signaling|positive regulation of transcription from RNA polymerase II promoter|negative regulation of lipid catabolic process|protein homotetramerization|energy homeostasis|",molecular_function|cAMP response element binding protein binding|,10,0.4,5.98,9,0.5,4.21,0.5,9.7,9.7,0.0166,0,0,0.2,1.1
ENSMUSG00000025758,PLK4,polo-like kinase 4,nucleus|nucleolus|cytoplasm|centrosome|centriole|cytoskeleton|deuterosome|,protein phosphorylation|centriole replication|centriole replication|phosphorylation|positive regulation of centriole replication|trophoblast giant cell differentiation|de novo centriole assembly|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|",10,0.6,7.49,10,-0.5,3.34,0.6,9.65,9.65,0.0167,0,0,0.2,1.4
ENSMUSG00000028849,MAP7D1,MAP7 domain containing 1,cytoplasm|cytoskeleton|microtubule|microtubule cytoskeleton|,microtubule cytoskeleton organization|biological_process|,molecular_function|,10,0.6,5.62,10,0.7,4.14,0.6,9.38,9.38,0.0174,0,0,0.2,1.1
ENSMUSG00000033411,CTDSPL2,"CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2",cellular_component|,biological_process|,"molecular_function|phosphoprotein phosphatase activity|protein tyrosine/serine/threonine phosphatase activity|protein tyrosine/threonine phosphatase activity|JUN kinase phosphatase activity|phosphohistidine phosphatase activity|inositol bisphosphate phosphatase activity|hydrolase activity|phosphatase activity|MAP kinase tyrosine/serine/threonine phosphatase activity|inositol-1,3,4-trisphosphate 4-phosphatase activity|NADP phosphatase activity|transmembrane receptor protein phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity|inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity|inositol-4,5-bisphosphate 5-phosphatase activity|5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity|phosphatidylinositol-4-phosphate phosphatase activity|phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|inositol phosphate phosphatase activity|inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity|inositol-3,4-bisphosphate 4-phosphatase activity|inositol-1,3,4-trisphosphate 1-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity|inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity|phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity|IDP phosphatase activity|",10,-1,10.3,10,-0.4,1.96,-0.8,9.37,-9.37,0.0174,0,0,-2,-0.3
ENSMUSG00000025646,ATRIP,ATR interacting protein,nucleus|microtubule cytoskeleton|,DNA repair|cellular response to DNA damage stimulus|,protein binding|,8,0,0,9,1.7,12.2,1.7,8.95,8.95,0.0187,0,0,0.5,3
ENSMUSG00000044408,SPTSSA,"serine palmitoyltransferase, small subunit A",endoplasmic reticulum|membrane|integral component of membrane|serine C-palmitoyltransferase complex|,lipid metabolic process|sphingolipid metabolic process|biological_process|,serine C-palmitoyltransferase activity|,10,1.1,4.21,10,1.5,5.21,1,8.71,8.71,0.0195,0,0,0.2,2.4
ENSMUSG00000042772,SMG7,"Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)",nucleus|cytoplasm|intermediate filament cytoskeleton|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|biological_process|",protein phosphatase 2A binding|,8,-0.5,5.61,8,0.8,3.73,-0.7,8.47,-8.47,0.0204,0,0,-1.9,-0.1
ENSMUSG00000043923,CCDC84,coiled-coil domain containing 84,cellular_component|,biological_process|,molecular_function|,7,0.3,2.19,6,1.2,9.16,1.1,8.26,8.26,0.0211,0,0,0.3,1.9
ENSMUSG00000021028,MBIP,MAP3K12 binding inhibitory protein 1,nucleus|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|nucleolus|cytoplasm|,histone H3 acetylation|,protein binding|identical protein binding|,10,0.4,1.48,10,1.6,9.8,1.5,7.92,7.92,0.0223,0,0,0.6,3
ENSMUSG00000036934,4921524J17RIK,RIKEN cDNA 4921524J17 gene,cellular_component|,biological_process|,molecular_function|,10,-0.6,9.56,10,-0.1,0.13,-0.5,7.8,-7.8,0.0229,0,0,-1.2,-0.1
ENSMUSG00000040097,FLYWCH1,FLYWCH-type zinc finger 1,nucleus|cytoplasm|,biological_process|,molecular_function|DNA binding|metal ion binding|,10,0.5,4.15,10,0.9,4.34,0.5,7.74,7.74,0.0231,0,0,0.2,1.3
ENSMUSG00000021645,SMN1,survival motor neuron 1,nucleus|nucleus|nucleoplasm|nucleolus|cytoplasm|cytoplasm|cytosol|Cajal body|SMN complex|SMN-Sm protein complex|Gemini of coiled bodies|,mRNA processing|microtubule depolymerization|nervous system development|axonogenesis|RNA splicing|,RNA binding|protein binding|fibroblast growth factor binding|identical protein binding|,10,0.5,1.39,10,1.8,9.34,1.7,7.51,7.51,0.0243,0,0,0.3,2.9
ENSMUSG00000037119,D15ERTD621E,"DNA segment, Chr 15, ERATO Doi 621, expressed",cellular_component|,biological_process|,molecular_function|,10,0.4,4.22,10,0.8,4.63,0.5,7.5,7.5,0.0244,0,0,0.1,1.2
ENSMUSG00000026078,PDCL3,phosducin-like 3,cytoplasm|cytoplasm|,angiogenesis|positive regulation of endothelial cell proliferation|protein folding|apoptotic process|positive regulation of angiogenesis|regulation of peptidyl-tyrosine phosphorylation|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,vascular endothelial growth factor receptor 2 binding|protein binding involved in protein folding|,10,0.5,4.8,10,0.6,3.08,0.5,7.44,7.44,0.0246,0,0,0.1,1.2
ENSMUSG00000031813,MVB12A,multivesicular body subunit 12A,ESCRT I complex|nucleus|cytoplasm|endosome|cytosol|cytoskeleton|membrane|aggresome|vesicle|intracellular membrane-bounded organelle|extracellular vesicular exosome|,transport|protein transport|regulation of epidermal growth factor receptor signaling pathway|,lipid binding|SH3 domain binding|ubiquitin binding|,10,0.3,1.81,10,1.6,7.55,0.3,7.19,7.19,0.0261,0,0,0.1,2.5
ENSMUSG00000032553,SRPRB,"signal recognition particle receptor, B subunit",intracellular|cytoplasm|endoplasmic reticulum|cytoplasmic microtubule|membrane|integral component of membrane|,small GTPase mediated signal transduction|,nucleotide binding|GTP binding|ubiquitin protein ligase binding|,9,-0.4,2.43,9,1.1,9.99,1.1,6.85,6.85,0.0283,0,0,-0.5,2
ENSMUSG00000021932,RNASEH2B,"ribonuclease H2, subunit B",nucleus|ribonuclease H2 complex|ribonuclease H2 complex|,"in utero embryonic development|RNA catabolic process|ribonucleotide metabolic process|regulation of G2/M transition of mitotic cell cycle|negative regulation of gene expression|positive regulation of fibroblast proliferation|RNA phosphodiester bond hydrolysis, endonucleolytic|regulation of DNA damage checkpoint|",RNA-DNA hybrid ribonuclease activity|,10,0.8,0.858,10,2.1,8.01,0.9,6.85,6.85,0.0283,0,0,0.6,3.6
ENSMUSG00000038215,CEP44,centrosomal protein 44,spindle pole|cytoplasm|centrosome|cytoskeleton|,biological_process|,molecular_function|,10,0.7,6.18,10,1.3,1.14,0.7,6.82,6.82,0.0285,0,0,0.3,1.8
ENSMUSG00000074922,FAM122A,"family with sequence similarity 122, member A",cellular_component|,biological_process|,molecular_function|,9,0.5,5.49,9,-0.7,2.81,0.5,6.79,6.79,0.0288,0,0,-0.6,1.7
ENSMUSG00000032481,SMARCC1,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1",nuclear chromatin|XY body|intracellular|nucleus|nucleus|SWI/SNF complex|SWI/SNF complex|SWI/SNF complex|protein complex|npBAF complex|nBAF complex|,"DNA packaging|nucleosome disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|nervous system development|insulin receptor signaling pathway|organ morphogenesis|chromatin modification|ATP-dependent chromatin remodeling|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|DNA binding|chromatin binding|protein binding|nucleosomal DNA binding|protein N-terminus binding|,10,0.9,4.4,10,0.4,2.84,0.5,6.75,6.75,0.0292,0,0,0.1,1.4
ENSMUSG00000040325,VPRBP,Vpr (HIV-1) binding protein,nucleus|cytoplasm|COP9 signalosome|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|viral process|phosphorylation|chromatin modification|B cell differentiation|V(D)J recombination|cell competition in a multicellular organism|histone H2A-T120 phosphorylation|",nucleotide binding|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|histone kinase activity (H2A-T120 specific)|,10,-0.5,2.86,10,-0.8,4.27,-0.8,6.67,-6.67,0.0297,0,0,-1.8,0.5
ENSMUSG00000031015,SWAP70,SWA-70 protein,nucleus|cytoplasm|plasma membrane|membrane|cell projection|,somatic cell DNA recombination|isotype switching|,DNA binding|protein binding|ATP binding|,10,-0.2,1.43,10,-0.5,6.26,-0.4,6.64,-6.64,0.03,0,0,-1,0
ENSMUSG00000037210,FAM193A,"family with sequence similarity 193, member A",None,biological_process|,molecular_function|,10,-0.5,4.32,10,-0.4,2.81,-0.4,6.59,-6.59,0.0303,0,0,-1.2,-0.1
ENSMUSG00000049354,DCAF7,DDB1 and CUL4 associated factor 7,nucleus|cytoplasm|nuclear matrix|protein complex|Cul4-RING E3 ubiquitin ligase complex|,multicellular organismal development|,None,9,0,0,9,0.8,8.04,0.7,6.58,6.58,0.0305,0,0,0.2,1.7
ENSMUSG00000032120,C2CD2L,C2 calcium-dependent domain containing 2-like,membrane|integral component of membrane|,positive regulation of insulin secretion involved in cellular response to glucose stimulus|,insulin binding|,10,0.4,2.87,10,1.1,5.31,0.5,6.48,6.48,0.0314,0,0,0.1,1.7
ENSMUSG00000020919,STAT5B,signal transducer and activator of transcription 5B,nucleus|nucleus|cytoplasm|cytosol|,"allantoin metabolic process|luteinization|luteinization|natural killer cell differentiation|liver development|citrate metabolic process|2-oxoglutarate metabolic process|succinate metabolic process|oxaloacetate metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|isoleucine metabolic process|valine metabolic process|creatine metabolic process|fatty acid metabolic process|acute-phase response|signal transduction|JAK-STAT cascade|JAK-STAT cascade|sex differentiation|female pregnancy|female pregnancy|lactation|positive regulation of cell proliferation|regulation of steroid metabolic process|cytokine-mediated signaling pathway|taurine metabolic process|lipid storage|regulation of cell adhesion|regulation of epithelial cell differentiation|response to estradiol|response to lipopolysaccharide|positive regulation of natural killer cell proliferation|positive regulation of natural killer cell differentiation|cellular response to hormone stimulus|T cell differentiation in thymus|prolactin signaling pathway|regulation of multicellular organism growth|positive regulation of multicellular organism growth|positive regulation of multicellular organism growth|positive regulation of activated T cell proliferation|positive regulation of activated T cell proliferation|progesterone metabolic process|T cell homeostasis|negative regulation of apoptotic process|response to peptide hormone|positive regulation of interleukin-2 biosynthetic process|positive regulation of B cell differentiation|positive regulation of gamma-delta T cell differentiation|positive regulation of lymphocyte differentiation|negative regulation of erythrocyte differentiation|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of natural killer cell mediated cytotoxicity|creatinine metabolic process|development of secondary female sexual characteristics|development of secondary male sexual characteristics|development of secondary male sexual characteristics|Peyer's patch development|positive regulation of smooth muscle cell proliferation|positive regulation of inflammatory response|positive regulation of cellular component movement|JAK-STAT cascade involved in growth hormone signaling pathway|JAK-STAT cascade involved in growth hormone signaling pathway|response to interleukin-2|response to interleukin-4|response to interleukin-15|cellular response to growth factor stimulus|cellular response to epidermal growth factor stimulus|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|calcium ion binding|protein binding|protein phosphatase binding|glucocorticoid receptor binding|sequence-specific DNA binding|protein dimerization activity|,10,-0.6,6.96,10,0.2,0.603,-0.5,6.47,-6.47,0.0315,0,0,-1.5,0.1
ENSMUSG00000024037,WDR4,WD repeat domain 4,nucleus|nucleoplasm|cytoplasm|,tRNA modification|tRNA processing|RNA (guanine-N7)-methylation|,tRNA (guanine-N7-)-methyltransferase activity|,10,0.6,3,10,0.5,3.81,0.5,6.42,6.42,0.032,0,0,0,1.3
ENSMUSG00000049164,ZFP518A,zinc finger protein 518A,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.8,2.3,10,1.6,5.49,0.9,6.32,6.32,0.0329,0,0,0.2,2.8
ENSMUSG00000039929,URB1,URB1 ribosome biogenesis 1 homolog (S. cerevisiae),nucleus|nucleolus|,None,poly(A) RNA binding|,10,0.8,7.7,10,0.1,0.12,0.7,6.32,6.32,0.0329,0,0,0.1,1.7
ENSMUSG00000021555,NAA35,"N(alpha)-acetyltransferase 35, NatC auxiliary subunit",cytoplasm|cytoplasm|polysome|NatC complex|,negative regulation of apoptotic process|smooth muscle cell proliferation|,protein binding|,10,0.6,6.76,10,0.3,0.808,0.5,6.22,6.22,0.0337,0,0,0.1,1.4
ENSMUSG00000021176,EFCAB11,EF-hand calcium binding domain 11,cellular_component|,biological_process|,calcium ion binding|metal ion binding|,10,0.4,3.92,10,0.5,2.62,0.4,6.21,6.21,0.0338,0,0,0,1.3
ENSMUSG00000027652,RALGAPB,"Ral GTPase activating protein, beta subunit (non-catalytic)",intracellular|,Ral protein signal transduction|activation of Ral GTPase activity|activation of Ral GTPase activity|regulation of protein localization|regulation of small GTPase mediated signal transduction|regulation of exocyst localization|,GTPase activator activity|Ral GTPase activator activity|Ral GTPase activator activity|protein heterodimerization activity|,10,-0.5,4.77,10,-0.4,1.93,-0.5,6.13,-6.13,0.0346,0,0,-1.2,0
ENSMUSG00000059182,SKAP2,src family associated phosphoprotein 2,nucleus|cytoplasm|cytoplasm|plasma membrane|,negative regulation of cell proliferation|B cell activation|,None,10,0.3,1.1,10,1.5,6.71,0.7,6.04,6.04,0.0356,0,0,0.1,2.5
ENSMUSG00000034951,COG7,component of oligomeric golgi complex 7,Golgi apparatus|membrane|Golgi transport complex|,"protein glycosylation|transport|intracellular protein transport|retrograde vesicle-mediated transport, Golgi to ER|protein transport|protein localization to organelle|protein localization to Golgi apparatus|protein stabilization|",molecular_function|,9,0.8,6.5,9,-0.3,0.865,0.8,5.88,5.88,0.0373,0,0,0,2
ENSMUSG00000024976,SHOC2,soc-2 (suppressor of clear) homolog (C. elegans),protein phosphatase type 1 complex|nucleus|cytoplasm|,positive regulation of Ras protein signal transduction|,protein phosphatase binding|,10,-0.5,3.25,9,-0.9,3.57,-0.9,5.85,-5.85,0.0376,0,0,-1.7,-0.1
ENSMUSG00000015087,RABL6,"RAB, member RAS oncogene family-like 6",intracellular|nucleus|cytoplasm|,small GTPase mediated signal transduction|,nucleotide binding|GTP binding|,10,0.4,3.67,10,0.4,2.31,0.4,5.68,5.68,0.0394,0,0,0,1.2
ENSMUSG00000037443,CEP85,centrosomal protein 85,spindle pole|nucleus|nucleolus|cytoplasm|centrosome|cytoskeleton|,biological_process|,molecular_function|,10,-0.5,7.1,10,-0.1,0.0951,-0.5,5.67,-5.67,0.0395,0,0,-1.6,0
ENSMUSG00000044783,HJURP,Holliday junction recognition protein,"chromosome, centromeric region|nucleus|chromosome|",cell cycle|,DNA binding|histone binding|,10,0.9,5.28,10,-1.4,7.97,0.8,5.59,5.59,0.0405,0,0,-2.5,1.8
ENSMUSG00000057219,ARMC7,armadillo repeat containing 7,cytoplasm|,biological_process|,molecular_function|,9,-0.5,0.876,9,0.7,7.21,0.7,5.59,5.59,0.0405,0,0,-0.1,2.7
ENSMUSG00000036459,WTIP,WT1-interacting protein,cytoplasmic mRNA processing body|nucleus|cytoplasm|plasma membrane|membrane|cell junction|,"response to hypoxia|transcription, DNA-templated|regulation of transcription, DNA-templated|cytoskeleton organization|regulation of cell morphogenesis|gene silencing by RNA|gene silencing by miRNA|negative regulation of hippo signaling|positive regulation of gene silencing by miRNA|regulation of RNA biosynthetic process|",transcription corepressor activity|protein binding|zinc ion binding|metal ion binding|,10,0.5,7.42,10,0,0,0.5,5.52,5.52,0.0415,0,0,-0.1,1.4
ENSMUSG00000050721,PLEKHO2,"pleckstrin homology domain containing, family O member 2",cellular_component|,biological_process|,molecular_function|,10,0.3,4.52,10,0.3,1.15,0.3,5.41,5.41,0.0428,0,0,0,1.1
ENSMUSG00000015776,MED22,mediator complex subunit 22,nucleus|mediator complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription cofactor activity|,6,0.5,3.96,5,-0.9,2.94,0.5,5.39,5.39,0.0431,0,0,-0.9,2
ENSMUSG00000020897,AURKB,aurora kinase B,"chromosome, centromeric region|kinetochore|condensed chromosome, centromeric region|condensed nuclear chromosome, centromeric region|nucleus|chromosome|cytoplasm|spindle|cytoskeleton|chromocenter|midbody|midbody|chromosome passenger complex|chromosome passenger complex|intercellular bridge|mitotic spindle pole|",negative regulation of transcription from RNA polymerase II promoter|negative regulation of B cell apoptotic process|protein phosphorylation|cell cycle|mitotic nuclear division|phosphorylation|spindle checkpoint|negative regulation of protein binding|positive regulation of cytokinesis|protein localization to kinetochore|cellular response to UV|cleavage furrow formation|spindle stabilization|histone H3-S28 phosphorylation|spindle midzone assembly involved in mitosis|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|histone serine kinase activity|metal ion binding|",7,0.7,4.04,6,1.3,2.45,0.7,5.37,5.37,0.0434,0,0,-1.2,2
ENSMUSG00000025374,NABP2,nucleic acid binding protein 2,nucleus|SOSS complex|,double-strand break repair via homologous recombination|DNA repair|cellular response to DNA damage stimulus|mitotic cell cycle checkpoint|response to ionizing radiation|,nucleic acid binding|DNA binding|single-stranded DNA binding|,10,0,0,10,-1,8.13,-0.9,5.33,-5.33,0.044,0,0,-1.8,-0.1
ENSMUSG00000029464,GPN3,GPN-loop GTPase 3,protein complex|,biological_process|,nucleotide binding|molecular_function|GTP binding|,9,-0.8,3.41,8,-0.5,3.13,-0.6,5.28,-5.28,0.0447,0,0,-1.6,1.4
ENSMUSG00000022558,MROH1,maestro heat-like repeat family member 1,cellular_component|,biological_process|,molecular_function|,10,0.3,2.8,10,0.6,3.23,0.4,5.28,5.28,0.0447,0,0,0,1.2
ENSMUSG00000017734,DBNDD2,dysbindin (dystrobrevin binding protein 1) domain containing 2,cellular_component|cytoplasm|,negative regulation of protein kinase activity|,molecular_function|,10,0.5,2.34,9,0.7,3.21,0.6,5.22,5.22,0.0456,0,0,-0.2,1.5
ENSMUSG00000096351,SAMD11,sterile alpha motif domain containing 11,nucleus|,negative regulation of transcription from RNA polymerase II promoter|,SAM domain binding|PH domain binding|protein self-association|,10,0.1,0.506,10,1.7,8.28,1.6,5.22,5.22,0.0456,0,0,0.2,2.9
ENSMUSG00000032077,BUD13,BUD13 homolog (yeast),nucleus|,biological_process|,poly(A) RNA binding|,10,0.6,6.02,10,0.2,0.0879,0.5,5.08,5.08,0.0479,0,0,-0.1,1.5
ENSMUSG00000024426,ATAT1,alpha tubulin acetyltransferase 1,cytoplasm|cytoskeleton|coated pit|membrane|cell junction|cell projection|mitotic spindle|microtubule bundle|,spermatogenesis|dentate gyrus development|regulation of fat cell differentiation|alpha-tubulin acetylation|alpha-tubulin acetylation|positive regulation of NLRP3 inflammasome complex assembly|,"transferase activity|transferase activity, transferring acyl groups|tubulin N-acetyltransferase activity|tubulin N-acetyltransferase activity|coenzyme binding|",10,0.8,2.76,10,0.4,2.74,0.4,5.01,5.01,0.0492,0,0,-0.6,2
ENSMUSG00000044627,SWI5,SWI5 recombination repair homolog (yeast),nucleus|Swi5-Sfr1 complex|Swi5-Sfr1 complex|,double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|DNA repair|cellular response to DNA damage stimulus|cellular response to ionizing radiation|,protein binding|,10,1.2,2.72,10,0.8,3.33,1,5.01,5.01,0.0492,0,0,0.1,1.8
ENSMUSG00000025066,SFR1,SWI5 dependent recombination repair 1,nucleus|Swi5-Sfr1 complex|Swi5-Sfr1 complex|,double-strand break repair via homologous recombination|double-strand break repair via homologous recombination|DNA repair|cellular response to DNA damage stimulus|,molecular_function|,10,0.2,0.442,10,1,6.98,0.7,5,5,0.0494,0,0,0.1,1.8
ENSMUSG00000000976,HEATR6,HEAT repeat containing 6,cellular_component|,biological_process|,poly(A) RNA binding|,10,0.4,4.66,10,0.2,0.909,0.3,4.92,4.92,0.0511,0,0,-0.1,1.2
ENSMUSG00000064030,WIBG,within bgcn homolog (Drosophila),nucleus|cytoplasm|exon-exon junction complex|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of translation|positive regulation of translation|",ribosome binding|poly(A) RNA binding|,10,0.3,2.41,10,0.6,3.22,0.5,4.86,4.86,0.0523,0,0,-0.9,1.7
ENSMUSG00000055538,ZCCHC24,"zinc finger, CCHC domain containing 24",cellular_component|,regulation of gliogenesis|,nucleic acid binding|zinc ion binding|poly(A) RNA binding|metal ion binding|,10,0.3,0.929,10,-1.4,7.92,-1.4,4.85,-4.85,0.0525,0,0,-3,-0.1
ENSMUSG00000027502,RTFDC1,replication termination factor 2 domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.5,5.1,10,0.3,0.101,0.4,4.76,4.76,0.0542,0,0,-0.3,1.3
ENSMUSG00000066191,ANKS6,ankyrin repeat and sterile alpha motif domain containing 6,cytoplasm|cilium|cell projection|,None,protein homodimerization activity|,10,1.6,7.32,10,0.2,0.241,0.2,4.64,4.64,0.0569,0,0,0.1,2.9
ENSMUSG00000025902,SOX17,SRY (sex determining region Y)-box 17,nucleus|nucleus|transcription factor complex|nuclear transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|vasculogenesis|endoderm formation|inner cell mass cellular morphogenesis|heart looping|cardiogenic plate morphogenesis|embryonic heart tube morphogenesis|outflow tract morphogenesis|negative regulation of Wnt signaling pathway involved in heart development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|spermatogenesis|gastrulation|endoderm development|endodermal cell fate determination|positive regulation of gene expression|Wnt signaling pathway|rostrocaudal neural tube patterning|signal transduction involved in regulation of gene expression|negative regulation of Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of cell growth|protein destabilization|embryonic heart tube development|cell migration involved in gastrulation|regulation of mesodermal cell fate specification|negative regulation of mesodermal cell fate specification|mRNA transcription from RNA polymerase II promoter|regulation of cell differentiation|positive regulation of cell differentiation|positive regulation of cell differentiation|positive regulation of protein catabolic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|regulation of embryonic development|embryonic organ development|embryonic foregut morphogenesis|positive regulation of skeletal muscle tissue development|stem cell differentiation|stem cell fate specification|protein stabilization|canonical Wnt signaling pathway|endocardium formation|regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification|cardiac cell fate determination|endocardial cell differentiation|common bile duct development|gall bladder development|endodermal digestive tract morphogenesis|renal system development|regulation of stem cell proliferation|negative regulation of canonical Wnt signaling pathway|regulation of stem cell division|regulation of cardiac cell fate specification|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription coactivator activity|protein binding|beta-catenin binding|transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,1.3,3.38,10,0.4,1.79,1.2,4.62,4.62,0.0574,0,0,0.2,2
ENSMUSG00000018572,PHF23,PHD finger protein 23,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.4,2.88,10,-1.1,3.83,-0.6,4.59,-4.59,0.0582,0,0,-1.9,1
ENSMUSG00000061079,ZFP143,zinc finger protein 143,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|protein binding|metal ion binding|,10,0.4,2.05,10,0.4,2.8,0.4,4.57,4.57,0.0587,0,0,-0.1,1.9
ENSMUSG00000047656,TRPT1,tRNA phosphotransferase 1,cellular_component|,"tRNA splicing, via endonucleolytic cleavage and ligation|tRNA processing|regulation of protein kinase activity|","tRNA 2'-phosphotransferase activity|2'-phosphotransferase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,3.55,10,0.7,1.99,0.5,4.57,4.57,0.0587,0,0,0,1.4
ENSMUSG00000028614,NDC1,NDC1 transmembrane nucleoporin,nucleus|nuclear pore|nuclear pore|cytoplasm|membrane|membrane|integral component of membrane|,transport|synapsis|spermatogenesis|protein transport|nuclear pore distribution|mRNA transport|nuclear pore complex assembly|,structural constituent of nuclear pore|,10,0.4,4.17,10,0.2,0.893,0.3,4.43,4.43,0.0618,0,0,-0.2,1.6
ENSMUSG00000063882,UQCRH,ubiquinol-cytochrome c reductase hinge protein,mitochondrion|mitochondrial inner membrane|mitochondrial respiratory chain complex III|membrane|respiratory chain|,"mitochondrial electron transport, ubiquinol to cytochrome c|transport|protein heterooligomerization|oxidation-reduction process|",ubiquinol-cytochrome-c reductase activity|protein complex binding|,9,0.9,0.937,9,-1.2,7.66,-1.2,4.42,-4.42,0.0621,0,0,-2,0.6
ENSMUSG00000041408,WAPAL,wings apart-like homolog (Drosophila),chromatin|chromatin|synaptonemal complex|nucleus|chromosome|cytoplasm|cohesin complex|microtubule cytoskeleton|intracellular membrane-bounded organelle|,cell cycle|mitotic nuclear division|mitotic nuclear division|negative regulation of DNA replication|response to toxic substance|negative regulation of chromatin binding|negative regulation of sister chromatid cohesion|positive regulation of fibroblast proliferation|cell division|regulation of chromosome segregation|regulation of chromosome condensation|protein localization to chromatin|regulation of cohesin localization to chromatin|regulation of cohesin localization to chromatin|,molecular_function|,10,0.1,0.0238,10,0.5,5.64,0.5,4.4,4.4,0.0625,0,0,-0.3,1.4
ENSMUSG00000034832,TET3,tet methylcytosine dioxygenase 3,female pronucleus|male pronucleus|nucleus|cytoplasm|,protein O-linked glycosylation|multicellular organismal development|chromatin modification|DNA demethylation of male pronucleus|positive regulation of transcription from RNA polymerase II promoter|oxidation-reduction process|DNA demethylation|DNA demethylation|histone H3-K4 trimethylation|,DNA binding|protein binding|oxidoreductase activity|metal ion binding|dioxygenase activity|methylcytosine dioxygenase activity|methylcytosine dioxygenase activity|,9,0.5,5.17,9,0.1,0.233,0.4,4.34,4.34,0.0642,0,0,-0.1,1.5
ENSMUSG00000078810,GP6,glycoprotein 6 (platelet),integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,blood coagulation|hemostasis|,collagen binding|,10,0.5,2.66,10,0.5,1.92,0.5,4.32,4.32,0.0646,0,0,-0.1,1.7
ENSMUSG00000049957,CCDC137,coiled-coil domain containing 137,cellular_component|,biological_process|,poly(A) RNA binding|,9,0.3,1.55,9,0.8,3.86,0.4,4.28,4.28,0.0657,0,0,0,1.8
ENSMUSG00000073856,IQCK,IQ motif containing K,cellular_component|,biological_process|,molecular_function|,10,0.4,3.18,10,0.3,1.57,0.3,4.25,4.25,0.0665,0,0,-0.3,1.2
ENSMUSG00000034773,BC030867,cDNA sequence BC030867,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.84,10,-1,2.17,-0.7,4.24,-4.24,0.0667,0,0,-1.8,0
ENSMUSG00000031458,COPRS,"coordinator of PRMT5, differentiation stimulator",nucleus|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|muscle organ development|chromatin modification|histone H4-R3 methylation|",protein binding|histone binding|,10,0.5,2.69,10,0.3,2.03,0.4,4.24,4.24,0.0667,0,0,-0.1,1.4
ENSMUSG00000030609,AEN,apoptosis enhancing nuclease,nucleus|nucleoplasm|nucleolus|nuclear membrane|,apoptotic process|cellular response to DNA damage stimulus|response to ionizing radiation|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|nucleic acid phosphodiester bond hydrolysis|,nucleic acid binding|nuclease activity|exonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,1.2,7.01,10,-1.2,1.03,1.1,4.17,4.17,0.0685,0,0,-0.8,2
ENSMUSG00000074994,QSER1,glutamine and serine rich 1,cellular_component|,biological_process|,molecular_function|,10,0.2,0.605,10,0.9,5.12,0.4,4.12,4.12,0.07,0,0,-0.1,1.8
ENSMUSG00000052915,MSL1,male-specific lethal 1 homolog (Drosophila),nucleus|MSL complex|,chromatin modification|histone H4-K16 acetylation|,molecular_function|,10,-0.6,4.8,10,-0.2,1.13,-0.5,4.08,-4.08,0.0711,0,0,-1.6,0.2
ENSMUSG00000024101,WASH,WAS protein family homolog,intracellular|cell|endosome|early endosome|early endosome|membrane|recycling endosome|WASH complex|,"transport|endosomal transport|Arp2/3 complex-mediated actin nucleation|Arp2/3 complex-mediated actin nucleation|retrograde transport, endosome to Golgi|",actin binding|ubiquitin protein ligase binding|alpha-tubulin binding|,10,-0.2,1.38,10,-0.9,5.14,-0.9,4.07,-4.07,0.0713,0,0,-1.8,0.1
ENSMUSG00000010290,AI597479,expressed sequence AI597479,tRNA-splicing ligase complex|,biological_process|embryonic morphogenesis|,molecular_function|,10,0.5,2.78,10,0.8,1.84,0.7,4.04,4.04,0.0722,0,0,-0.2,1.7
ENSMUSG00000029386,TCTN2,tectonic family member 2,cytoplasm|cytoskeleton|membrane|integral component of membrane|TCTN-B9D complex|cell projection|,smoothened signaling pathway|cell projection organization|cilium assembly|cilium morphogenesis|,protein binding|,10,-1.3,7.11,10,0.2,0.354,-1.2,3.98,-3.98,0.0742,0,0,-2,0.2
ENSMUSG00000031691,TNPO2,"transportin 2 (importin 3, karyopherin beta 2b)",nucleus|cytoplasm|,transport|intracellular protein transport|protein transport|,protein binding|Ran GTPase binding|,10,-0.3,2.11,10,-0.4,2.12,-0.3,3.97,-3.97,0.0745,0,0,-1.2,0.3
ENSMUSG00000073471,RSPH3A,radial spoke 3A homolog (Chlamydomonas),cellular_component|,biological_process|,molecular_function|,9,0.5,5,9,0.1,0.0918,0.4,3.95,3.95,0.0752,0,0,-0.2,1.5
ENSMUSG00000025995,WDR75,WD repeat domain 75,nucleus|,biological_process|,poly(A) RNA binding|,8,-0.8,3.86,7,-0.4,0.943,-0.6,3.95,-3.95,0.0752,0,0,-1.9,1
ENSMUSG00000031072,ORAOV1,oral cancer overexpressed 1,cellular_component|,biological_process|,molecular_function|,10,0.7,4.52,10,-0.4,2,0.6,3.94,3.94,0.0756,0,0,-0.8,1.6
ENSMUSG00000020485,SUPT4A,suppressor of Ty 4A,nucleus|DSIF complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription elongation from RNA polymerase II promoter|negative regulation of DNA-templated transcription, elongation|positive regulation of DNA-templated transcription, elongation|negative regulation of transcription elongation from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",zinc ion binding|metal ion binding|protein heterodimerization activity|,10,-0.7,4.43,10,-0.2,0.441,-0.6,3.92,-3.92,0.0763,0,0,-1.8,0.7
ENSMUSG00000021981,CAB39L,calcium binding protein 39-like,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.9,3.34,10,-1.2,1.26,-1.1,3.89,-3.89,0.0772,0,0,-2,1
ENSMUSG00000056268,DENND1B,DENN/MADD domain containing 1B,cellular_component|cytoplasm|cytoplasmic vesicle|,transport|protein transport|positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,0.5,2.89,9,0.3,1.57,0.3,3.81,3.81,0.0798,0,0,-0.2,1.4
ENSMUSG00000073069,MAGEB2,"melanoma antigen, family B, 2",cellular_component|,biological_process|,molecular_function|,10,-0.3,2.25,10,-0.3,1.8,-0.3,3.8,-3.8,0.0801,0,0,-1.5,0.5
ENSMUSG00000031971,CCSAP,"centriole, cilia and spindle associated protein",cytoplasm|centrosome|centriole|spindle|cytoskeleton|cilium|axoneme|axon|ciliary transition zone|ciliary basal body|cell projection|,multicellular organismal development|biological_process|,molecular_function|,9,1.2,6.17,10,-0.1,0.237,1.1,3.79,3.79,0.0805,0,0,0,2
ENSMUSG00000052142,RASAL3,RAS protein activator like 3,intracellular|cytoplasm|membrane|intrinsic component of the cytoplasmic side of the plasma membrane|extracellular vesicular exosome|,signal transduction|positive regulation of Ras GTPase activity|negative regulation of Ras protein signal transduction|regulation of small GTPase mediated signal transduction|,GTPase activator activity|Ras GTPase activator activity|,9,0.5,4,9,0.2,0.617,0.4,3.76,3.76,0.0817,0,0,-0.2,1.4
ENSMUSG00000037379,SPON2,"spondin 2, extracellular matrix protein",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|extracellular vesicular exosome|,immune system process|mast cell mediated immunity|cell adhesion|opsonization|opsonization|response to lipopolysaccharide|positive regulation of interleukin-6 production|positive regulation of interleukin-6 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|defense response to bacterium|induction of bacterial agglutination|innate immune response|defense response to fungus|defense response to virus|positive regulation of macrophage cytokine production|positive regulation of macrophage cytokine production|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|,lipopolysaccharide binding|antigen binding|antigen binding|receptor binding|protein binding|metal ion binding|,10,-0.3,1.9,10,1.9,7.16,1.8,3.64,3.64,0.0859,0,0,-0.2,3
ENSMUSG00000017550,ATAD5,"ATPase family, AAA domain containing 5",cellular_component|nucleus|,cellular response to DNA damage stimulus|biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0.4,3.09,10,0.2,1.02,0.3,3.62,3.62,0.0867,0,0,-0.6,1.6
ENSMUSG00000025264,TSR2,TSR2 20S rRNA accumulation,cellular_component|,rRNA processing|biological_process|,molecular_function|,8,-0.2,0.281,9,0.6,4.25,0.6,3.6,3.6,0.0875,0,0,-0.8,1.9
ENSMUSG00000091649,PHF11B,PHD finger protein 11B,cellular_component|,biological_process|,molecular_function|metal ion binding|,8,-0.5,3.94,8,-0.2,0.294,-0.4,3.6,-3.6,0.0875,0,0,-1.7,0.2
ENSMUSG00000034560,A230046K03RIK,RIKEN cDNA A230046K03 gene,intracellular|cell|endosome|endosome|WASH complex|,endosomal transport|endosomal transport|,molecular_function|,10,-0.1,0.039,10,-0.5,4.44,-0.5,3.53,-3.53,0.0904,0,0,-1.8,1.3
ENSMUSG00000020864,ANKRD40,ankyrin repeat domain 40,cellular_component|,biological_process|,molecular_function|,10,0.6,4.03,10,0.2,1.21,0.4,3.53,3.53,0.0904,0,0,-1,1.6
ENSMUSG00000002222,RMND5A,required for meiotic nuclear division 5 homolog A (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,1.1,2.43,10,0.8,1.55,1,3.52,3.52,0.0909,0,0,0,1.9
ENSMUSG00000020102,SLC16A7,"solute carrier family 16 (monocarboxylic acid transporters), member 7",cytoplasm|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|organic anion transport|lactate transmembrane transport|plasma membrane lactate transport|transmembrane transport|pyruvate transmembrane transport|,lactate transmembrane transporter activity|symporter activity|secondary active monocarboxylate transmembrane transporter activity|pyruvate transmembrane transporter activity|,10,-1.2,5.77,10,0.1,0.0894,-0.2,3.48,-3.48,0.0926,0,0,-2,0
ENSMUSG00000038122,TBC1D32,"TBC1 domain family, member 32",cellular_component|cytoplasm|cilium|cell projection|,lens development in camera-type eye|retinal pigment epithelium development|smoothened signaling pathway|multicellular organismal development|neural tube development|regulation of Rab GTPase activity|axoneme assembly|embryonic digit morphogenesis|camera-type eye development|retina development in camera-type eye|cilium morphogenesis|smoothened signaling pathway involved in dorsal/ventral neural tube patterning|protein localization to cilium|,Rab GTPase activator activity|protein binding|,10,0.1,0.211,10,0.7,3.85,0.6,3.41,3.41,0.0955,0,0,-0.1,1.9
ENSMUSG00000023829,SLC22A1,"solute carrier family 22 (organic cation transporter), member 1",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,transport|ion transport|cation transport|neurotransmitter transport|drug transmembrane transport|establishment or maintenance of transmembrane electrochemical gradient|organic cation transport|organic cation transport|quaternary ammonium group transport|monoamine transport|dopamine transport|norepinephrine transport|ion transmembrane transport|epinephrine transport|protein homooligomerization|transmembrane transport|acetate ester transport|,transporter activity|acetylcholine transmembrane transporter activity|dopamine transmembrane transporter activity|norepinephrine transmembrane transporter activity|monoamine transmembrane transporter activity|secondary active organic cation transmembrane transporter activity|ion transmembrane transporter activity|organic cation transmembrane transporter activity|organic cation transmembrane transporter activity|quaternary ammonium group transmembrane transporter activity|transmembrane transporter activity|identical protein binding|protein homodimerization activity|,10,0.4,3.85,10,0,0,0.4,3.4,3.4,0.0959,0,0,-0.2,1.5
ENSMUSG00000027067,SSRP1,structure specific recognition protein 1,nucleus|chromosome|cytoplasm|,"DNA replication|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|biological_process|",DNA binding|chromatin binding|poly(A) RNA binding|,8,0.3,1.8,8,0.5,2.1,0.3,3.39,3.39,0.0963,0,0,-1.4,1.7
ENSMUSG00000027109,SP3,trans-acting transcription factor 3,nucleus|transcriptional repressor complex|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|ossification|in utero embryonic development|natural killer cell differentiation|trophectodermal cell differentiation|liver development|embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|B cell differentiation|T cell differentiation|erythrocyte differentiation|megakaryocyte differentiation|monocyte differentiation|lung development|granulocyte differentiation|enucleate erythrocyte differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|embryonic camera-type eye morphogenesis|embryonic skeletal system development|embryonic process involved in female pregnancy|definitive hemopoiesis|",RNA polymerase II core promoter sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|DNA binding|chromatin binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|metal ion binding|,10,0.4,3.52,10,-0.1,0.484,0.3,3.37,3.37,0.0972,0,0,-0.2,1.8
ENSMUSG00000027690,SLC2A2,"solute carrier family 2 (facilitated glucose transporter), member 2",cytoplasm|cytoplasm|endosome|cytosol|plasma membrane|plasma membrane|brush border|brush border|membrane|integral component of membrane|basolateral plasma membrane|brush border membrane|,transport|carbohydrate transport|carbohydrate utilization|glucose transport|glucose transport|glucose transport|hexose transmembrane transport|transmembrane transport|dehydroascorbic acid transport|dehydroascorbic acid transport|,insulin receptor binding|transporter activity|glucose transmembrane transporter activity|glucose transmembrane transporter activity|transmembrane transporter activity|substrate-specific transmembrane transporter activity|dehydroascorbic acid transporter activity|dehydroascorbic acid transporter activity|D-glucose transmembrane transporter activity|D-glucose transmembrane transporter activity|,10,0,0,10,1,4.58,1,3.36,3.36,0.0977,0,0,-0.1,2
ENSMUSG00000071379,HPCAL1,hippocalcin-like 1,extracellular vesicular exosome|,biological_process|,calcium ion binding|protein binding|metal ion binding|,10,0.4,2.24,10,0.4,1.35,0.4,3.36,3.36,0.0977,0,0,-0.4,1.4
ENSMUSG00000046546,FAM43A,"family with sequence similarity 43, member A",cellular_component|,biological_process|,molecular_function|,9,0.1,0.0094,9,-0.5,4.23,-0.5,3.34,-3.34,0.0984,0,0,-1.7,0.4
ENSMUSG00000055670,ZZEF1,"zinc finger, ZZ-type with EF hand domain 1",cellular_component|,biological_process|,molecular_function|calcium ion binding|zinc ion binding|metal ion binding|,10,0.4,2.28,10,0.3,1.27,0.3,3.33,3.33,0.0989,0,0,-0.3,1.4
ENSMUSG00000025332,KDM5C,lysine (K)-specific demethylase 5C,intracellular|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H3-K4 demethylation|oxidation-reduction process|","sulfonate dioxygenase activity|RNA polymerase II transcription factor binding|DNA binding|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|histone demethylase activity (H3-K4 specific)|hypophosphite dioxygenase activity|identical protein binding|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,-0.5,1.94,10,-0.4,1.65,-0.4,3.25,-3.25,0.102,0,0,-1.6,0.9
ENSMUSG00000005982,NAA60,"N(alpha)-acetyltransferase 60, NatF catalytic subunit",Golgi membrane|Golgi apparatus|membrane|,nucleosome assembly|chromosome segregation|cell proliferation|chromatin modification|N-terminal peptidyl-methionine acetylation|histone H4 acetylation|,"histone acetyltransferase activity|peptide alpha-N-acetyltransferase activity|N-acetyltransferase activity|H4 histone acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",4,-0.6,1.29,4,-0.6,2.18,-0.6,3.25,-3.25,0.102,0,0,-2,0.4
ENSMUSG00000040842,SZRD1,SUZ RNA binding domain containing 1,cellular_component|,biological_process|,molecular_function|,8,-0.7,4.79,6,-0.1,0.136,-0.6,3.22,-3.22,0.104,0,0,-1.9,0.3
ENSMUSG00000025609,MKLN1,"muskelin 1, intracellular mediator containing kelch motifs",cytoplasm|,None,protein binding|,10,-0.3,0.725,10,-0.8,3.97,-0.4,3.19,-3.19,0.106,0,0,-1.7,0.6
ENSMUSG00000044715,GSKIP,GSK3B interacting protein,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.5,1.5,10,0.4,1.96,0.5,3.19,3.19,0.106,0,0,-1,1.5
ENSMUSG00000031221,IGBP1,immunoglobulin (CD79A) binding protein 1,cytoplasm|microtubule|,negative regulation of transcription from RNA polymerase II promoter|regulation of signal transduction|negative regulation of stress-activated MAPK cascade|response to tumor necrosis factor|positive regulation of dephosphorylation|negative regulation of protein dephosphorylation|B cell activation|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of transcription from RNA polymerase II promoter|regulation of microtubule-based movement|response to interleukin-1|negative regulation of apoptotic signaling pathway|,protein binding|protein phosphatase type 2A regulator activity|protein domain specific binding|mitogen-activated protein kinase kinase binding|,9,0.9,3.56,8,0.1,0.297,0.5,3.17,3.17,0.106,0,0,-0.6,1.9
ENSMUSG00000001376,CCDC132,coiled-coil domain containing 132,membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,0.357,10,1.7,5.81,1.6,3.15,3.15,0.107,0,0,-0.1,3
ENSMUSG00000022249,TTC23L,tetratricopeptide repeat domain 23-like,cellular_component|,biological_process|,molecular_function|,10,0.5,3.83,10,0.1,0.311,0.4,3.13,3.13,0.108,0,0,-0.3,1.6
ENSMUSG00000054302,EAPP,E2F-associated phosphoprotein,nucleus|cytoplasm|Golgi apparatus|,positive regulation of cell proliferation|positive regulation of transcription elongation from RNA polymerase II promoter|negative regulation of transcription elongation from RNA polymerase II promoter|,molecular_function|,10,0.7,3.05,10,0.4,0.643,0.7,3.11,3.11,0.109,0,0,-0.4,1.8
ENSMUSG00000023892,ZFP51,zinc finger protein 51,None,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.5,2.18,10,0.6,1.13,0.5,3.09,3.09,0.11,0,0,-0.5,1.5
ENSMUSG00000029004,KMT2E,lysine (K)-specific methyltransferase 2E,nucleus|MLL5-L complex|,"neutrophil mediated immunity|DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|cell cycle arrest|chromatin modification|peptidyl-lysine methylation|erythrocyte differentiation|positive regulation of granulocyte differentiation|methylation|neutrophil activation|positive regulation of transcription, DNA-templated|retinoic acid receptor signaling pathway|histone H3-K4 methylation|cellular response to retinoic acid|",transcription coactivator activity|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|enzyme binding|histone methyltransferase activity (H3-K4 specific)|metal ion binding|,10,-0.6,2.41,10,-0.4,1.08,-0.6,2.99,-2.99,0.116,0,0,-1.7,0.3
ENSMUSG00000068663,CLEC16A,"C-type lectin domain family 16, member A",cellular_component|,biological_process|,molecular_function|,10,0.4,3.76,10,0.1,0.0165,0.3,2.98,2.98,0.116,0,0,-0.5,1.4
ENSMUSG00000044098,RSBN1,"rosbin, round spermatid basic protein 1",nucleus|,biological_process|,protein binding|,10,0.7,4.95,10,-1.1,3.1,0.6,2.97,2.97,0.117,0,0,-1.7,1.6
ENSMUSG00000038039,GCC2,GRIP and coiled-coil domain containing 2,nucleus|cytoplasm|Golgi apparatus|trans-Golgi network|membrane|membrane|,"protein targeting to Golgi|protein targeting to lysosome|transport|protein transport|microtubule organizing center organization|protein localization to Golgi apparatus|microtubule anchoring|late endosome to Golgi transport|retrograde transport, endosome to Golgi|regulation of protein exit from endoplasmic reticulum|recycling endosome to Golgi transport|Golgi ribbon formation|",protein binding|identical protein binding|,10,0.6,4.67,10,0,0,0.3,2.95,2.95,0.118,0,0,-0.1,1.7
ENSMUSG00000019868,VTA1,Vps20-associated 1 homolog (S. cerevisiae),cytoplasm|endosome|membrane|extracellular vesicular exosome|,transport|protein transport|,protein binding|,10,-0.1,0.209,10,-0.5,3.59,-0.3,2.93,-2.93,0.119,0,0,-1.5,0.5
ENSMUSG00000078453,ABRACL,ABRA C-terminal like,cellular_component|,biological_process|,molecular_function|,10,0.4,3.13,10,0.1,0.529,0.3,2.91,2.91,0.12,0,0,-0.3,1.5
ENSMUSG00000042203,TBC1D22B,"TBC1 domain family, member 22B",cellular_component|,biological_process|,molecular_function|,9,-0.3,1.84,9,-0.2,1.43,-0.3,2.91,-2.91,0.12,0,0,-1.5,0.6
ENSMUSG00000038848,YTHDF1,YTH domain family 1,cellular_component|,biological_process|,RNA binding|poly(A) RNA binding|N6-methyladenosine-containing RNA binding|,10,-0.4,3.09,10,-0.8,0.0132,-0.4,2.9,-2.9,0.121,0,0,-1.8,0.6
ENSMUSG00000058914,C1QTNF3,C1q and tumor necrosis factor related protein 3,extracellular region|collagen trimer|extracellular space|membrane|extracellular vesicular exosome|,negative regulation of gene expression|cellular triglyceride homeostasis|negative regulation of NF-kappaB import into nucleus|glucose homeostasis|negative regulation of gluconeogenesis|negative regulation of gluconeogenesis|positive regulation of cytokine secretion|positive regulation of cytokine secretion|negative regulation of inflammatory response|protein oligomerization|positive regulation of protein kinase B signaling|positive regulation of adiponectin secretion|positive regulation of adiponectin secretion|protein trimerization|positive regulation of ERK1 and ERK2 cascade|negative regulation of monocyte chemotactic protein-1 production|negative regulation of interleukin-6 secretion|,identical protein binding|,10,-0.2,1.08,10,-0.4,2.66,-0.3,2.89,-2.89,0.122,0,0,-1.4,0.5
ENSMUSG00000028291,AKIRIN2,akirin 2,nucleus|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|immune system process|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|positive regulation of cell proliferation|embryo development|negative regulation of gene expression|positive regulation of endopeptidase activity|response to lipopolysaccharide|positive regulation of interleukin-6 production|innate immune response|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|",enzyme binding|,10,1.7,5.07,10,-0.4,2.3,1.6,2.87,2.87,0.123,0,0,-0.4,3
ENSMUSG00000005374,TBL2,transducin (beta)-like 2,cellular_component|,biological_process|,poly(A) RNA binding|,10,0.2,0.484,10,1.9,4.88,1.9,2.85,2.85,0.124,0,0,0,3
ENSMUSG00000029337,FGF5,fibroblast growth factor 5,extracellular region|,cell proliferation|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|glial cell differentiation|signal transduction involved in regulation of gene expression|positive regulation of cell division|,receptor binding|fibroblast growth factor receptor binding|growth factor activity|,9,-0.2,0.447,10,-1,3.2,-0.5,2.84,-2.84,0.124,0,0,-1.9,0.3
ENSMUSG00000071653,1810009A15RIK,RIKEN cDNA 1810009A15 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,3.87,10,0.1,0.241,0.4,2.82,2.82,0.125,0,0,-0.5,1.6
ENSMUSG00000070837,AURKC,aurora kinase C,"chromosome, centromeric region|condensed chromosome|nucleus|chromosome|cytoplasm|cytoskeleton|midbody|spindle midzone|",protein phosphorylation|cell cycle|mitotic nuclear division|meiotic nuclear division|phosphorylation|cell division|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.324,10,-1.3,4.7,-0.3,2.82,-2.82,0.125,0,0,-2,0
ENSMUSG00000036912,PIWIL4,piwi-like RNA-mediated gene silencing 4,nucleus|cytoplasm|P granule|piP-body|,regulation of translation|meiotic nuclear division|multicellular organismal development|spermatogenesis|cell differentiation|gene silencing by RNA|piRNA metabolic process|piRNA metabolic process|DNA methylation involved in gamete generation|,nucleic acid binding|RNA binding|protein binding|piRNA binding|,10,0.3,2.2,10,0.4,0.839,0.3,2.79,2.79,0.127,0,0,-0.5,1.4
ENSMUSG00000050914,ANKRD37,ankyrin repeat domain 37,nucleus|cytoplasm|,biological_process|,protein binding|,10,-0.3,1.31,10,-0.3,1.66,-0.3,2.78,-2.78,0.128,0,0,-1.5,0.4
ENSMUSG00000029821,DFNA5,"deafness, autosomal dominant 5 (human)",cytoplasm|,apoptotic process|sensory perception of sound|negative regulation of cell proliferation|inner ear receptor cell differentiation|positive regulation of intrinsic apoptotic signaling pathway|,None,10,0.3,3.12,10,-0.1,0.0634,0.3,2.78,2.78,0.128,0,0,-0.6,1.4
ENSMUSG00000024878,CBWD1,COBW domain containing 1,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0.2,2.3,10,0.3,0.631,0.3,2.75,2.75,0.13,0,0,-0.4,1.5
ENSMUSG00000018287,SPAG7,sperm associated antigen 7,nucleus|,biological_process|,molecular_function|nucleic acid binding|,10,0.4,2.11,10,0.3,0.819,0.3,2.72,2.72,0.132,0,0,-0.4,2
ENSMUSG00000055368,SLC6A2,"solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2",plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|neuron projection|membrane raft|,transport|neurotransmitter transport|monoamine transport|norepinephrine transport|response to pain|transmembrane transport|,neurotransmitter:sodium symporter activity|norepinephrine transmembrane transporter activity|monoamine transmembrane transporter activity|symporter activity|alpha-tubulin binding|beta-tubulin binding|,10,0.4,2.35,10,0.3,0.577,0.3,2.72,2.72,0.132,0,0,-0.7,1.4
ENSMUSG00000041671,PYROXD1,pyridine nucleotide-disulphide oxidoreductase domain 1,cellular_component|,oxidation-reduction process|,molecular_function|alkyl hydroperoxide reductase activity|oxidoreductase activity|,10,0.8,3.51,10,-1.2,1.9,0.8,2.71,2.71,0.132,0,0,-1.6,1.7
ENSMUSG00000070883,CCDC173,coiled-coil domain containing 173,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.14,10,-0.6,2.26,-0.5,2.69,-2.69,0.134,0,0,-1.6,0.5
ENSMUSG00000040738,INTS8,integrator complex subunit 8,nucleus|integrator complex|,snRNA processing|,molecular_function|,10,0.5,2.53,10,0.2,0.679,0.4,2.68,2.68,0.134,0,0,-0.7,1.6
ENSMUSG00000000732,ICOSL,icos ligand,integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,immune system process|signal transduction|positive regulation of activated T cell proliferation|T cell activation|B cell activation|isotype switching|positive regulation of interleukin-4 biosynthetic process|,receptor binding|protein binding|,10,0.3,2.17,10,0.2,0.738,0.3,2.66,2.66,0.135,0,0,-0.6,1.4
ENSMUSG00000074704,RAD21L,RAD21-like (S. pombe),nuclear chromosome|lateral element|nucleus|chromosome|meiotic cohesin complex|nuclear meiotic cohesin complex|,double-strand break repair via homologous recombination|double-strand break repair|chromosome segregation|meiotic nuclear division|synapsis|spermatogenesis|fertilization|linear element assembly|attachment of telomeric heterochromatin to nuclear envelope|seminiferous tubule development|,molecular_function|,10,0.5,4.37,10,-0.4,1.21,0.4,2.64,2.64,0.137,0,0,-0.8,1.5
ENSMUSG00000024098,TWSG1,twisted gastrulation homolog 1 (Drosophila),extracellular region|extracellular space|extracellular vesicular exosome|,ossification|mesoderm formation|multicellular organismal development|salivary gland morphogenesis|embryo development|tissue development|hemopoiesis|cell differentiation|BMP signaling pathway|positive regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|forebrain development|forebrain development|camera-type eye development|negative regulation of osteoblast differentiation|,protein binding|,10,0.2,0.289,10,0.5,3.51,0.4,2.63,2.63,0.138,0,0,-0.4,1.5
ENSMUSG00000027286,LRRC57,leucine rich repeat containing 57,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.4,1.4,10,-0.2,1.63,-0.3,2.61,-2.61,0.139,0,0,-1.6,0.5
ENSMUSG00000066366,SERPINA1A,"serine (or cysteine) peptidase inhibitor, clade A, member 1A",extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|extracellular vesicular exosome|,protein N-linked glycosylation|acute-phase response|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,glycoprotein binding|protease binding|endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|protein binding|peptidase inhibitor activity|identical protein binding|,10,-0.5,4.78,10,0,0,-0.4,2.61,-2.61,0.139,0,0,-1.6,0.7
ENSMUSG00000022911,ARL13B,ADP-ribosylation factor-like 13B,intracellular|plasma membrane|cilium|cilium|membrane|cell projection|ciliary membrane|primary cilium|,heart looping|smoothened signaling pathway|small GTPase mediated signal transduction|multicellular organismal development|determination of left/right symmetry|dorsal/ventral pattern formation|neural tube patterning|interneuron migration from the subpallium to the cortex|formation of radial glial scaffolds|nonmotile primary cilium assembly|cilium assembly|left/right axis specification|,nucleotide binding|GTP binding|,10,0.4,2.55,10,0.2,0.652,0.3,2.6,2.6,0.14,0,0,-0.6,1.7
ENSMUSG00000018238,GDF9,growth differentiation factor 9,extracellular region|extracellular space|cytoplasm|,oocyte growth|positive regulation of cell proliferation|negative regulation of cell growth|regulation of progesterone secretion|,cytokine activity|growth factor activity|,10,-0.3,2.65,10,-0.1,0.518,-0.2,2.58,-2.58,0.141,0,0,-1.4,0.7
ENSMUSG00000067795,4930444P10RIK,RIKEN cDNA 4930444P10 gene,cellular_component|,biological_process|,molecular_function|,10,0.6,0.527,10,-0.3,2.52,-0.2,2.58,-2.58,0.141,0,0,-1.2,1.4
ENSMUSG00000044250,PCED1B,PC-esterase domain containing 1B,cellular_component|,biological_process|,molecular_function|hydrolase activity|,10,-0.2,0.923,10,-0.7,2.95,-0.3,2.56,-2.56,0.143,0,0,-1.8,0.2
ENSMUSG00000029682,SPAM1,sperm adhesion molecule 1,acrosomal vesicle|plasma membrane|external side of plasma membrane|membrane|anchored component of membrane|membrane raft|,carbohydrate metabolic process|cell adhesion|single fertilization|fusion of sperm to egg plasma membrane|metabolic process|,"catalytic activity|hyalurononglucosaminidase activity|hyalurononglucosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,-0.1,0.112,10,-0.4,2.87,-0.3,2.56,-2.56,0.143,0,0,-1.5,0.8
ENSMUSG00000042250,PGLYRP4,peptidoglycan recognition protein 4,cellular_component|extracellular region|,pattern recognition receptor signaling pathway|immune system process|peptidoglycan catabolic process|detection of bacterium|negative regulation of interferon-gamma production|negative regulation of natural killer cell differentiation involved in immune response|defense response to bacterium|growth of symbiont in host|innate immune response|defense response to Gram-positive bacterium|,zinc ion binding|N-acetylmuramoyl-L-alanine amidase activity|peptidoglycan receptor activity|peptidoglycan binding|,10,0.2,1.53,10,0.2,1.22,0.2,2.56,2.56,0.143,0,0,-0.8,1.3
ENSMUSG00000021403,SERPINB9B,"serine (or cysteine) peptidase inhibitor, clade B, member 9b",cytoplasm|,negative regulation of endopeptidase activity|cytolysis|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|protein binding|,10,0.3,2.55,10,0.2,0.268,0.3,2.55,2.55,0.144,0,0,-0.6,1.4
ENSMUSG00000068745,MYBPHL,myosin binding protein H-like,cellular_component|,biological_process|,molecular_function|,10,-1,0.531,10,1.6,3.04,-1.1,2.55,-2.55,0.144,0,0,-2,2.3
ENSMUSG00000020973,DNAAF2,"dynein, axonemal assembly factor 2",cytoplasm|ciliary basal body|,response to organic substance|response to retinoic acid|cilium-dependent cell motility|axonemal dynein complex assembly|bacterial-type flagellum-dependent cell motility|,protein binding|,10,0.5,3.62,10,-0.1,0.198,0.5,2.53,2.53,0.145,0,0,-0.6,1.7
ENSMUSG00000095810,GM14478,predicted gene 14478,cellular_component|,biological_process|,molecular_function|,10,-0.4,0.714,10,-0.4,1.98,-0.4,2.52,-2.52,0.146,0,0,-1.6,0.6
ENSMUSG00000096097,GM14477,predicted gene 14477,cellular_component|,biological_process|,molecular_function|,10,-0.4,0.714,10,-0.4,1.98,-0.4,2.52,-2.52,0.146,0,0,-1.6,0.6
ENSMUSG00000095662,GM14482,predicted gene 14482,cellular_component|,biological_process|,molecular_function|,10,-0.4,0.714,10,-0.4,1.98,-0.4,2.52,-2.52,0.146,0,0,-1.6,0.6
ENSMUSG00000094904,GM14476,predicted gene 14476,cellular_component|,biological_process|,molecular_function|,10,-0.4,0.714,10,-0.4,1.98,-0.4,2.52,-2.52,0.146,0,0,-1.6,0.6
ENSMUSG00000051851,CXX1C,CAAX box 1C,cellular_component|,biological_process|,molecular_function|,10,0.3,0.987,10,0.4,1.73,0.3,2.51,2.51,0.146,0,0,-0.8,1.7
ENSMUSG00000046671,MTFR1L,mitochondrial fission regulator 1-like,cellular_component|,biological_process|,molecular_function|,10,0.4,2.61,10,0.2,0.497,0.3,2.51,2.51,0.146,0,0,-0.6,1.5
ENSMUSG00000026917,WDR5,WD repeat domain 5,histone acetyltransferase complex|intracellular|nucleus|nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|histone methyltransferase complex|Set1C/COMPASS complex|MLL1 complex|,"skeletal system development|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter|histone H3 acetylation|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|rhythmic process|histone H3-K4 methylation|histone H3-K4 methylation|",protein binding|histone methyltransferase activity (H3-K4 specific)|histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|histone acetyltransferase activity (H4-K16 specific)|,8,0,0,7,1.4,4.32,0.7,2.46,2.46,0.15,0,0,-0.2,2.9
ENSMUSG00000090641,ZFP712,zinc finger protein 712,cellular_component|,"regulation of transcription, DNA-templated|",sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.4,1.97,10,0.2,0.928,0.3,2.43,2.43,0.153,0,0,-0.6,1.6
ENSMUSG00000002699,LCP2,lymphocyte cytosolic protein 2,cell|cytoplasm|cell-cell junction|,mast cell activation|cytokine secretion|,None,10,0.3,2.35,10,0.2,0.321,0.3,2.43,2.43,0.153,0,0,-0.6,1.6
ENSMUSG00000022404,SLC25A17,"solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17",cytoplasm|mitochondrion|peroxisome|peroxisomal membrane|peroxisomal membrane|integral component of peroxisomal membrane|membrane|membrane|integral component of membrane|intracellular membrane-bounded organelle|,fatty acid beta-oxidation|transport|ADP transport|ATP transport|fatty acid transport|coenzyme A transmembrane transport|FAD transmembrane transport|NAD transport|transmembrane transport|AMP transport|nucleotide transmembrane transport|,ATP transmembrane transporter activity|ADP transmembrane transporter activity|coenzyme A transmembrane transporter activity|FAD transmembrane transporter activity|FMN transmembrane transporter activity|chaperone binding|NAD transporter activity|AMP transmembrane transporter activity|,10,0,0,10,-0.4,4.27,-0.3,2.42,-2.42,0.153,0,0,-1.8,0.4
ENSMUSG00000028245,NSMAF,neutral sphingomyelinase (N-SMase) activation associated factor,None,positive regulation of apoptotic process|positive regulation of catalytic activity|,death receptor binding|sphingomyelin phosphodiesterase activator activity|,10,-0.2,0.535,10,-0.3,2.07,-0.3,2.4,-2.4,0.155,0,0,-1.5,0.6
ENSMUSG00000058240,CRYZL1,"crystallin, zeta (quinone reductase)-like 1",cytosol|,oxidation-reduction process|,zinc ion binding|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.3,0.773,10,0.4,1.97,0.3,2.4,2.4,0.155,0,0,-0.7,1.5
ENSMUSG00000050390,C77080,expressed sequence C77080,cellular_component|,biological_process|,molecular_function|,10,0.3,2.73,10,0.1,0.00637,0.2,2.38,2.38,0.157,0,0,-0.9,1.4
ENSMUSG00000043439,E130012A19RIK,RIKEN cDNA E130012A19 gene,cellular_component|,neuron fate commitment|neuron fate commitment|,protein binding|,10,-0.5,2.15,10,-0.3,0.539,-0.5,2.38,-2.38,0.157,0,0,-1.6,0.5
ENSMUSG00000048126,COL6A3,"collagen, type VI, alpha 3",collagen trimer|extracellular space|extracellular space|extracellular matrix|extracellular matrix|extracellular matrix|sarcolemma|extracellular vesicular exosome|,None,None,10,-0.4,2.28,10,-1.3,2.17,-0.3,2.37,-2.37,0.158,0,0,-2,0.6
ENSMUSG00000031563,WWC2,"WW, C2 and coiled-coil domain containing 2",cytosol|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of hippo signaling|negative regulation of organ growth|,kinase binding|protein complex scaffold|,10,1.3,3.19,10,-0.4,0.842,-0.3,2.34,-2.34,0.16,0,0,-0.9,2
ENSMUSG00000059022,KCP,kielin/chordin-like protein,extracellular region|extracellular space|,hematopoietic progenitor cell differentiation|positive regulation of BMP signaling pathway|,protein binding|,10,0.3,1.6,10,0.4,0.966,0.4,2.34,2.34,0.16,0,0,-0.6,1.8
ENSMUSG00000085079,KHDC1B,KH domain containing 1B,cytoplasm|,activation of cysteine-type endopeptidase activity involved in apoptotic process|,RNA binding|protein binding|identical protein binding|,10,0.3,1.06,10,0.5,1.73,0.4,2.32,2.32,0.162,0,0,-0.7,1.5
ENSMUSG00000037525,BCDIN3D,BCDIN3 domain containing,nucleus|cytoplasm|,RNA methylation|miRNA metabolic process|methylation|negative regulation of pre-miRNA processing|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.3,1.88,10,0.3,0.612,0.3,2.32,2.32,0.162,0,0,-0.5,1.5
ENSMUSG00000071647,EML3,echinoderm microtubule associated protein like 3,cellular_component|cytoplasm|cytoskeleton|microtubule|,biological_process|,molecular_function|,10,0.3,1.98,10,0.2,0.644,0.2,2.29,2.29,0.164,0,0,-0.6,1.5
ENSMUSG00000044700,TMEM201,transmembrane protein 201,cell|nucleus|membrane|integral component of membrane|nuclear membrane|,nuclear migration|fibroblast migration|,protein binding|lamin binding|actin filament binding|,9,0.7,4.56,10,0.1,0.138,0.7,2.29,2.29,0.164,0,0,-0.2,1.9
ENSMUSG00000036104,RAB3GAP1,RAB3 GTPase activating protein subunit 1,cytoplasm|extracellular vesicular exosome|,brain development|hypothalamus development|positive regulation of Rab GTPase activity|lipid particle organization|camera-type eye development|regulation of GTPase activity|face morphogenesis|,GTPase activator activity|Rab GTPase activator activity|Rab GTPase binding|,10,0.5,0.978,10,0.6,1.5,0.5,2.28,2.28,0.165,0,0,-0.5,1.7
ENSMUSG00000035545,LENG8,leukocyte receptor cluster (LRC) member 8,cellular_component|,biological_process|,None,10,0.2,0.855,10,0.5,1.9,0.3,2.28,2.28,0.165,0,0,-0.9,1.5
ENSMUSG00000037638,ZBTB42,zinc finger and BTB domain containing 42,nucleus|nucleus|nucleoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|,10,0.3,2.34,10,0.3,0.0757,0.3,2.28,2.28,0.165,0,0,-0.5,1.5
ENSMUSG00000050930,MAP10,microtubule-associated protein 10,cytoplasm|centrosome|cytoskeleton|cytoplasmic microtubule|midbody|mitotic spindle pole|mitotic spindle midzone|,microtubule cytoskeleton organization|cell cycle|cytoplasmic microtubule organization|positive regulation of cytokinesis|regulation of microtubule-based process|spindle midzone assembly involved in mitosis|cell division|,microtubule binding|,10,0.3,1.35,10,0.3,1.1,0.3,2.28,2.28,0.165,0,0,-0.6,1.6
ENSMUSG00000040859,BSDC1,BSD domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.2,0.652,10,0.4,2.09,0.3,2.27,2.27,0.166,0,0,-0.5,1.8
ENSMUSG00000096393,GM590,predicted gene 590,cellular_component|,biological_process|,molecular_function|,10,-0.5,4.31,10,0,0,-0.4,2.2,-2.2,0.173,0,0,-1.7,0.6
ENSMUSG00000047940,STPG2,sperm tail PG rich repeat containing 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,3.29,0.4,2.19,2.19,0.174,0,0,-0.2,1.9
ENSMUSG00000022359,WDYHV1,WDYHV motif containing 1,nucleus|cytoplasm|cytosol|,cellular protein modification process|protein catabolic process|,"histone deacetylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|protein-N-terminal glutamine amidohydrolase activity|",10,0.2,0.605,10,0.2,1.74,0.2,2.19,2.19,0.174,0,0,-1,1.4
ENSMUSG00000038712,FAM63A,"family with sequence similarity 63, member A",extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,1.41,10,0.4,0.942,0.3,2.18,2.18,0.175,0,0,-0.5,1.6
ENSMUSG00000020186,CSRP2,cysteine and glycine-rich protein 2,nucleus|,multicellular organismal development|cell differentiation|,protein binding|zinc ion binding|metal ion binding|,10,-0.3,2.15,10,-0.2,0.408,-0.3,2.17,-2.17,0.176,0,0,-1.5,0.7
ENSMUSG00000032172,OLFM2,olfactomedin 2,extracellular region|cell|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|,protein secretion|,molecular_function|,10,0.2,0.751,10,0.4,1.8,0.3,2.17,2.17,0.176,0,0,-0.7,1.6
ENSMUSG00000048617,RTBDN,retbindin,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.2,1.17,10,0.8,1.21,0.2,2.17,2.17,0.176,0,0,-0.6,1.8
ENSMUSG00000020538,SREBF1,sterol regulatory element binding transcription factor 1,nucleus|nucleus|cytoplasm|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|regulation of heart rate by chemical signal|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|lipid metabolic process|steroid metabolic process|cholesterol metabolic process|insulin receptor signaling pathway|lipid biosynthetic process|cellular response to starvation|cellular response to starvation|response to glucose|positive regulation of triglyceride biosynthetic process|positive regulation of triglyceride biosynthetic process|regulation of fatty acid metabolic process|positive regulation of histone deacetylation|positive regulation of cholesterol biosynthetic process|positive regulation of fatty acid biosynthetic process|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of insulin secretion|regulation of insulin secretion|",DNA binding|chromatin binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein kinase binding|protein complex binding|sterol response element binding|sterol response element binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein dimerization activity|,9,1.5,3.33,9,0.3,1.43,1.3,2.16,2.16,0.176,0,0,-0.3,3
ENSMUSG00000036282,NAA30,"N(alpha)-acetyltransferase 30, NatC catalytic subunit",cytoplasm|polysome|NatC complex|,metabolic process|,"peptide alpha-N-acetyltransferase activity|N-acetyltransferase activity|transferase activity|transferase activity, transferring acyl groups|",9,0.6,1.88,9,-0.4,3.68,-0.3,2.16,-2.16,0.176,0,0,-1.3,1.5
ENSMUSG00000002504,SLC9A3R2,"solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2",nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|membrane|apical plasma membrane|apical plasma membrane|protein complex|extracellular vesicular exosome|,negative regulation of phosphatidylinositol 3-kinase signaling|positive regulation of membrane potential|,receptor binding|protein binding|beta-catenin binding|protein C-terminus binding|channel regulator activity|phosphatase binding|phosphatase binding|PDZ domain binding|protein complex scaffold|low-density lipoprotein particle receptor binding|,10,0.3,1.67,10,0.3,0.613,0.3,2.13,2.13,0.179,0,0,-0.6,1.5
ENSMUSG00000034471,CASKIN2,CASK-interacting protein 2,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.2,1.47,10,0.2,0.809,0.2,2.12,2.12,0.18,0,0,-0.6,1.5
ENSMUSG00000026730,PTER,phosphotriesterase related,extracellular vesicular exosome|,catabolic process|,"nuclease activity|zinc ion binding|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|",10,0.4,2.69,10,0,0,0.3,2.11,2.11,0.181,0,0,-0.9,1.5
ENSMUSG00000045374,WDR81,WD repeat domain 81,cellular_component|,negative regulation of phosphatase activity|,"molecular_function|transferase activity, transferring phosphorus-containing groups|",10,0.2,0.972,10,0.5,1.74,0.3,2.11,2.11,0.181,0,0,-0.4,1.6
ENSMUSG00000004359,SPIC,Spi-C transcription factor (Spi-1/PU.1 related),nucleus|,"blastocyst development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,0,0,10,0.5,3.66,0.4,2.08,2.08,0.184,0,0,-0.7,1.8
ENSMUSG00000050824,SSTR5,somatostatin receptor 5,cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|positive regulation of cytokinesis|somatostatin signaling pathway|glucose homeostasis|regulation of insulin secretion|,signal transducer activity|G-protein coupled receptor activity|somatostatin receptor activity|protein binding|,10,1.2,1.56,10,0.3,1.39,0.3,2.05,2.05,0.187,0,0,-0.3,2
ENSMUSG00000024052,LPIN2,lipin 2,nucleus|cytoplasm|endoplasmic reticulum|endoplasmic reticulum membrane|cytosol|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|lipid metabolic process|fatty acid metabolic process|dephosphorylation|positive regulation of transcription from RNA polymerase II promoter|",transcription coactivator activity|phosphatidate phosphatase activity|hydrolase activity|,10,0.3,2.34,10,0.1,0.287,0.3,2.05,2.05,0.187,0,0,-0.6,1.6
ENSMUSG00000031577,TTI2,TELO2 interacting protein 2,cellular_component|,biological_process|,molecular_function|,10,0.4,2.32,10,0.1,0.101,0.4,2.05,2.05,0.187,0,0,-0.6,1.6
ENSMUSG00000032381,FAM96A,"family with sequence similarity 96, member A",nucleus|cytoplasm|,chromosome segregation|biological_process|,molecular_function|metal ion binding|,10,0.2,0.993,10,0.7,2.13,0.2,2.05,2.05,0.187,0,0,-0.5,1.7
ENSMUSG00000038646,FAM103A1,"family with sequence similarity 103, member A1",nucleus|mRNA cap binding complex|,7-methylguanosine mRNA capping|methylation|recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex|,RNA binding|poly(A) RNA binding|,1,0,0,1,-0.8,2.66,-0.7,2.04,-2.04,0.188,0,0,-2,1.5
ENSMUSG00000031148,GPKOW,G patch domain and KOW motifs,nucleus|,biological_process|,molecular_function|nucleic acid binding|,9,-0.3,1.49,8,0.8,2.47,-0.3,2.04,-2.04,0.188,0,0,-1.5,1.6
ENSMUSG00000020392,CDKN2AIPNL,CDKN2A interacting protein N-terminal like,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.114,10,-0.4,2.46,-0.3,2.04,-2.04,0.188,0,0,-1.6,0.6
ENSMUSG00000037085,TRMT12,tRNA methyltranferase 12,cellular_component|,tRNA processing|biological_process|,molecular_function|transferase activity|,10,0.3,0.332,10,0.6,2.31,0.5,2.02,2.02,0.19,0,0,-0.7,1.7
ENSMUSG00000046691,CHTF8,"CTF8, chromosome transmission fidelity factor 8",cellular_component|nucleus|,DNA replication|cell cycle|biological_process|,molecular_function|DNA binding|,10,-0.2,0.94,10,-0.3,1.31,-0.3,2.02,-2.02,0.19,0,0,-1.3,1.4
ENSMUSG00000050052,TDRP,testis development related protein,nucleus|cytoplasm|,spermatogenesis|,molecular_function|,10,-0.2,1.08,10,-0.2,1.1,-0.2,2.02,-2.02,0.19,0,0,-1.3,1.2
ENSMUSG00000014498,ANKRD52,ankyrin repeat domain 52,cellular_component|,biological_process|,molecular_function|,10,0.3,2.69,10,0,0,0.3,2.01,2.01,0.191,0,0,-0.8,1.5
ENSMUSG00000062162,MAGEB1,"melanoma antigen, family B, 1",cellular_component|,biological_process|,molecular_function|,10,-0.2,1.27,10,-0.3,1.02,-0.3,2,-2,0.192,0,0,-1.6,1.1
ENSMUSG00000040771,OARD1,O-acyl-ADP-ribose deacylase 1,cellular_component|,purine nucleoside metabolic process|,"purine nucleoside binding|histone deacetylase activity|protein-N-terminal asparagine amidohydrolase activity|UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity|hydrolase activity|iprodione amidohydrolase activity|(3,5-dichlorophenylurea)acetate amidohydrolase activity|deacetylase activity|4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity|didemethylisoproturon amidohydrolase activity|N-isopropylacetanilide amidohydrolase activity|N-cyclohexylformamide amidohydrolase activity|isonicotinic acid hydrazide hydrolase activity|cis-aconitamide amidase activity|gamma-N-formylaminovinylacetate hydrolase activity|N2-acetyl-L-lysine deacetylase activity|O-succinylbenzoate synthase activity|indoleacetamide hydrolase activity|N-acetylcitrulline deacetylase activity|N-acetylgalactosamine-6-phosphate deacetylase activity|diacetylchitobiose deacetylase activity|chitooligosaccharide deacetylase activity|",10,-0.2,0.409,10,0.4,2.24,0.3,2,2,0.192,0,0,-0.7,1.9
ENSMUSG00000054951,9130008F23RIK,RIKEN cDNA 9130008F23 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.788,10,0.8,1.48,0.2,1.99,1.99,0.193,0,0,-0.7,1.8
ENSMUSG00000037750,FAM222B,"family with sequence similarity 222, member B",cellular_component|,biological_process|,molecular_function|,10,0.4,0.216,10,0.3,1.93,0.3,1.99,1.99,0.193,0,0,-0.4,1.9
ENSMUSG00000073664,NBEAL1,neurobeachin like 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0491,10,0.4,2.56,0.4,1.98,1.98,0.194,0,0,-0.6,1.9
ENSMUSG00000021819,ZSWIM8,zinc finger SWIM-type containing 8,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.4,2.37,10,0,0,0.3,1.96,1.96,0.196,0,0,-0.7,1.6
ENSMUSG00000011589,FSD1,fibronectin type 3 and SPRY domain-containing protein,intracellular|nucleus|cytoplasm|cytoskeleton|microtubule|,cell cycle|mitotic nuclear division|cell division|,None,10,0.3,2.71,10,-0.2,0.561,0.2,1.95,1.95,0.197,0,0,-0.8,1.5
ENSMUSG00000026634,ANGEL2,angel homolog 2 (Drosophila),cellular_component|,biological_process|,molecular_function|,10,-0.1,0.044,10,-1,3.33,-0.6,1.94,-1.94,0.198,0,0,-2,0.4
ENSMUSG00000029304,SPP1,secreted phosphoprotein 1,extracellular region|extracellular space|cytoplasm|membrane-bounded vesicle|cell projection|apical part of cell|perinuclear region of cytoplasm|extracellular vesicular exosome|,ossification|osteoblast differentiation|cell adhesion|response to organic substance|positive regulation of cell-substrate adhesion|neutrophil chemotaxis|neutrophil chemotaxis|biomineral tissue development|response to vitamin D|negative regulation of apoptotic process|positive regulation of bone resorption|response to steroid hormone|,cytokine activity|extracellular matrix binding|,10,-0.1,0.229,10,-0.4,3.16,-0.3,1.94,-1.94,0.198,0,0,-1.6,0.6
ENSMUSG00000042677,ZC3H12A,zinc finger CCCH type containing 12A,nucleus|cytoplasm|,angiogenesis|apoptotic process|multicellular organismal development|positive regulation of autophagy|positive regulation of autophagy|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|negative regulation of gene expression|positive regulation of lipid storage|positive regulation of lipid storage|cell differentiation|negative regulation of NF-kappaB transcription factor activity|negative regulation of NF-kappaB transcription factor activity|negative regulation of interleukin-6 production|negative regulation of interleukin-6 production|negative regulation of tumor necrosis factor production|negative regulation of tumor necrosis factor production|negative regulation of nitric oxide biosynthetic process|negative regulation of nitric oxide biosynthetic process|positive regulation of fat cell differentiation|positive regulation of fat cell differentiation|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|positive regulation of reactive oxygen species metabolic process|positive regulation of reactive oxygen species metabolic process|,nuclease activity|endonuclease activity|protein binding|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0.2,0.832,10,0.4,1.49,0.3,1.91,1.91,0.202,0,0,-0.5,1.6
ENSMUSG00000035790,CEP19,centrosomal protein 19,spindle pole|cytoplasm|centriole|cytoskeleton|,biological_process|,molecular_function|,10,0.2,1.35,10,0.3,0.688,0.2,1.89,1.89,0.204,0,0,-1.1,1.4
ENSMUSG00000063080,GM14501,predicted gene 14501,nucleosome|cellular_component|nucleus|chromosome|,biological_process|,molecular_function|DNA binding|,7,-0.7,0.365,7,-0.4,2.01,-0.4,1.88,-1.88,0.205,0,0,-1.9,0.9
ENSMUSG00000046991,WDR27,WD repeat domain 27,nucleus|,biological_process|,molecular_function|,10,-0.6,3.8,10,0,0,-0.4,1.83,-1.83,0.211,0,0,-1.9,0.5
ENSMUSG00000013158,4933405L10RIK,RIKEN cDNA 4933405L10 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,1.43,10,0.3,0.663,0.2,1.83,1.83,0.211,0,0,-0.9,1.5
ENSMUSG00000072969,ARMCX5,"armadillo repeat containing, X-linked 5",cellular_component|,biological_process|,molecular_function|,10,-0.9,4.53,10,-0.1,0.0975,-0.9,1.82,-1.82,0.212,0,0,-2,0.3
ENSMUSG00000031847,1700030J22RIK,RIKEN cDNA 1700030J22 gene,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.4,0.233,10,0.3,1.65,0.3,1.76,1.76,0.22,0,0,-0.6,1.6
ENSMUSG00000026532,SPTA1,"spectrin alpha, erythrocytic 1",cytoplasm|cytoskeleton|spectrin|spectrin|spectrin-associated cytoskeleton|spectrin-associated cytoskeleton|membrane|cortical cytoskeleton|cuticular plate|,lymphocyte homeostasis|porphyrin-containing compound biosynthetic process|plasma membrane organization|regulation of cell shape|actin cytoskeleton organization|hemopoiesis|positive regulation of protein binding|positive regulation of T cell proliferation|actin filament capping|,actin binding|calcium ion binding|metal ion binding|protein heterodimerization activity|,10,-0.2,1.51,10,-0.3,0.443,-0.2,1.76,-1.76,0.22,0,0,-1.6,0.7
ENSMUSG00000040818,DENND6A,DENN/MADD domain containing 6A,cytoplasm|endosome|recycling endosome|,positive regulation of Rab GTPase activity|positive regulation of cell-cell adhesion mediated by cadherin|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.1,0.286,9,-0.3,2.1,-0.2,1.75,-1.75,0.221,0,0,-1.7,0.7
ENSMUSG00000022972,1110004E09RIK,RIKEN cDNA 1110004E09 gene,nucleus|cytoplasm|cytosol|,biological_process|,molecular_function|,7,0.9,3.56,8,0.2,0.353,0.8,1.73,1.73,0.224,0,0,-0.6,2
ENSMUSG00000047642,D930020B18RIK,RIKEN cDNA D930020B18 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.755,10,0.3,1.18,0.2,1.73,1.73,0.224,0,0,-0.7,1.7
ENSMUSG00000029163,EMILIN1,elastin microfibril interfacer 1,extracellular region|proteinaceous extracellular matrix|collagen trimer|extracellular matrix|extracellular vesicular exosome|,cell adhesion|positive regulation of cell-substrate adhesion|extracellular matrix organization|,protein binding|extracellular matrix constituent conferring elasticity|identical protein binding|,10,-0.4,3.13,10,0.1,0.00241,-0.3,1.72,-1.72,0.225,0,0,-1.6,0.8
ENSMUSG00000038005,2700029M09RIK,RIKEN cDNA 2700029M09 gene,nucleus|,biological_process|,molecular_function|,9,-0.2,0.846,9,0.8,1.63,-0.3,1.71,-1.71,0.226,0,0,-1.1,1.7
ENSMUSG00000020956,DTD2,D-tyrosyl-tRNA deacylase 2,cellular_component|cytoplasm|,biological_process|D-amino acid catabolic process|,"molecular_function|nuclease activity|hydrolase activity|hydrolase activity, acting on ester bonds|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|",9,0.9,1.99,8,0.3,0.483,0.3,1.7,1.7,0.227,0,0,-0.9,2
ENSMUSG00000040591,1110051M20RIK,RIKEN cDNA 1110051M20 gene,nucleus|,biological_process|,molecular_function|,10,0.2,0.707,10,0.3,1.27,0.2,1.67,1.67,0.231,0,0,-0.8,1.6
ENSMUSG00000020299,4930524B15RIK,RIKEN cDNA 4930524B15 gene,cellular_component|,biological_process|,molecular_function|,9,0,0,9,0.4,2.06,0.4,1.66,1.66,0.233,0,0,-0.4,2
ENSMUSG00000041328,PCF11,cleavage and polyadenylation factor subunit homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0.4,0.601,10,-1.1,2.55,-0.2,1.63,-1.63,0.237,0,0,-2,0.9
ENSMUSG00000037904,ANKRD9,ankyrin repeat domain 9,cellular_component|,biological_process|,molecular_function|hydrolase activity|,10,0.2,0.9,10,0.2,0.862,0.2,1.63,1.63,0.237,0,0,-0.7,1.6
ENSMUSG00000061175,FNIP2,folliculin interacting protein 2,intracellular|nucleus|cytoplasm|cytoplasm|microtubule organizing center|plasma membrane|,negative regulation of transcription from RNA polymerase II promoter|regulation of protein phosphorylation|protein phosphorylation|cellular response to DNA damage stimulus|intrinsic apoptotic signaling pathway in response to DNA damage|positive regulation of peptidyl-serine phosphorylation|,molecular_function|,10,0.8,2.14,10,-0.4,2.16,0.7,1.63,1.63,0.237,0,0,-1,1.8
ENSMUSG00000047986,PALM3,paralemmin 3,cellular_component|cytoplasm|plasma membrane|membrane|,negative regulation of cytokine-mediated signaling pathway|Toll signaling pathway|response to lipopolysaccharide|,nucleotide binding|molecular_function|ATP binding|,9,0.1,0.051,9,0.4,2.26,0.3,1.62,1.62,0.238,0,0,-0.6,1.9
ENSMUSG00000020523,FAM114A2,"family with sequence similarity 114, member A2",cellular_component|,biological_process|,molecular_function|,10,0.3,2.39,10,0.1,0.00128,0.3,1.61,1.61,0.239,0,0,-0.5,1.7
ENSMUSG00000048832,VPS37C,vacuolar protein sorting 37C (yeast),ESCRT I complex|endosome|membrane|extracellular vesicular exosome|,transport|protein transport|,molecular_function|,10,0.3,1.78,10,-0.1,0.176,0.2,1.6,1.6,0.241,0,0,-0.3,2
ENSMUSG00000031163,GLOD5,glyoxalase domain containing 5,cellular_component|,biological_process|,molecular_function|,10,0.2,0.315,10,0.2,1.38,0.2,1.58,1.58,0.243,0,0,-0.7,1.7
ENSMUSG00000008333,SNRPB2,U2 small nuclear ribonucleoprotein B,nucleus|spliceosomal complex|ribonucleoprotein complex|catalytic step 2 spliceosome|,"mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|protein binding|snRNA binding|,10,-0.1,0.0102,10,0.4,2.15,0.3,1.58,1.58,0.243,0,0,-0.5,1.8
ENSMUSG00000020265,SUMO3,SMT3 suppressor of mif two 3 homolog 3 (yeast),nucleus|cytoplasm|nuclear body|extracellular vesicular exosome|,protein sumoylation|protein sumoylation|protein localization to nucleus|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,SUMO ligase activity|,10,0.5,2.24,10,0.1,0.17,0.4,1.58,1.58,0.243,0,0,-1.4,1.6
ENSMUSG00000027961,LRRC39,leucine rich repeat containing 39,cellular_component|,biological_process|,molecular_function|,10,0.6,0.64,10,-0.4,1.84,-0.3,1.57,-1.57,0.245,0,0,-1.3,1.5
ENSMUSG00000028100,NUDT17,nudix (nucleoside diphosphate linked moiety X)-type motif 17,cellular_component|,biological_process|,"thiamine-pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|",10,0.4,0.841,10,-0.8,1.61,0.4,1.56,1.56,0.246,0,0,-1.5,1.7
ENSMUSG00000030691,FCHSD2,FCH and double SH3 domains 2,cellular_component|,biological_process|,molecular_function|,10,0.4,1.76,10,0.2,0.156,0.3,1.56,1.56,0.246,0,0,-0.9,1.6
ENSMUSG00000044581,4932415D10RIK,N/A,None,None,None,10,-0.4,2.7,10,0.7,2.33,-0.3,1.55,-1.55,0.248,0,0,-1.1,2
ENSMUSG00000022008,GPALPP1,GPALPP motifs containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.5,1.67,10,-0.2,0.319,-0.3,1.55,-1.55,0.248,0,0,-1.6,0.8
ENSMUSG00000028016,INTS12,integrator complex subunit 12,nucleus|integrator complex|,snRNA processing|,molecular_function|zinc ion binding|metal ion binding|,10,0.3,1.48,10,0.1,0.319,0.2,1.54,1.54,0.249,0,0,-1.6,1.3
ENSMUSG00000025722,WDR73,WD repeat domain 73,cellular_component|,biological_process|,molecular_function|,10,0.2,1.7,10,-0.5,0.268,0.2,1.53,1.53,0.251,0,0,-1.5,1.1
ENSMUSG00000026357,RGS18,regulator of G-protein signaling 18,cytoplasm|plasma membrane|,G-protein coupled receptor signaling pathway|regulation of G-protein coupled receptor protein signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|,10,0.4,0.824,10,-0.6,2.22,-0.4,1.52,-1.52,0.252,0,0,-1.6,1
ENSMUSG00000073758,SH3D21,SH3 domain containing 21,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.8,4.36,10,0,0,-0.8,1.49,-1.49,0.257,0,0,-2,0.4
ENSMUSG00000035572,DCAF10,DDB1 and CUL4 associated factor 10,Cul4-RING E3 ubiquitin ligase complex|,biological_process|,molecular_function|,9,0.3,1.49,9,0.2,0.272,0.3,1.49,1.49,0.257,0,0,-0.8,1.8
ENSMUSG00000024054,SMCHD1,SMC hinge domain containing 1,Barr body|chromosome|,dosage compensation by inactivation of X chromosome|chromosome organization|inactivation of X chromosome by DNA methylation|,ATP binding|,10,0.2,0.755,10,0.3,0.994,0.2,1.48,1.48,0.258,0,0,-0.5,1.8
ENSMUSG00000091144,PHF11C,PHD finger protein 11C,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.575,10,0.3,1.26,0.2,1.48,1.48,0.258,0,0,-0.9,1.5
ENSMUSG00000025241,FYCO1,FYVE and coiled-coil domain containing 1,lysosome|endosome|late endosome|autophagic vacuole|membrane|integral component of membrane|cytoplasmic vesicle|,transport|plus-end-directed vesicle transport along microtubule|,metal ion binding|,10,0.3,1.44,10,0.2,0.159,0.3,1.44,1.44,0.264,0,0,-0.6,1.7
ENSMUSG00000045211,NUDT18,nudix (nucleoside diphosphate linked moiety X)-type motif 18,cellular_component|,nucleotide metabolic process|dADP catabolic process|dGDP catabolic process|GDP catabolic process|,magnesium ion binding|hydrolase activity|8-oxo-dGDP phosphatase activity|8-oxo-GDP phosphatase activity|8-hydroxy-dADP phosphatase activity|metal ion binding|,10,-0.4,1.9,10,-0.1,0.178,-0.4,1.44,-1.44,0.264,0,0,-1.7,0.7
ENSMUSG00000049744,ARHGAP15,Rho GTPase activating protein 15,intracellular|cytoplasm|membrane|,signal transduction|regulation of cell shape|positive regulation of Rac GTPase activity|,GTPase activator activity|Rac GTPase activator activity|,10,0.3,0.812,10,0.2,0.822,0.2,1.44,1.44,0.264,0,0,-0.7,1.7
ENSMUSG00000051007,PDDC1,Parkinson disease 7 domain containing 1,extracellular region|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.3,0.671,10,-0.2,0.93,-0.2,1.43,-1.43,0.266,0,0,-1.5,1
ENSMUSG00000039660,D2WSU81E,"DNA segment, Chr 2, Wayne State University 81, expressed",cellular_component|,biological_process|,poly(A) RNA binding|,9,0.6,0.94,10,-0.4,1.19,-0.7,1.43,-1.43,0.266,0,0,-1.8,1.3
ENSMUSG00000054752,FSD1L,fibronectin type III and SPRY domain containing 1-like,cellular_component|intracellular|,biological_process|,molecular_function|,9,0,0,9,-0.5,2.66,-0.3,1.42,-1.42,0.267,0,0,-1.7,1.4
ENSMUSG00000039496,CDNF,cerebral dopamine neurotrophic factor,cellular_component|extracellular region|,biological_process|,molecular_function|growth factor activity|,10,0,0,10,0.3,2.84,0.2,1.42,1.42,0.267,0,0,-0.4,2
ENSMUSG00000042595,FAM199X,"family with sequence similarity 199, X-linked",cellular_component|,biological_process|,molecular_function|,9,0.5,0.539,10,0.2,1.03,0.2,1.4,1.4,0.271,0,0,-0.6,1.8
ENSMUSG00000034636,ZYG11B,"zyg-ll family member B, cell cycle regulator",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.4,3.15,0.3,1.39,1.39,0.272,0,0,-0.4,1.9
ENSMUSG00000029708,GCC1,golgi coiled coil 1,cytoplasm|Golgi apparatus|plasma membrane|membrane|,protein targeting to Golgi|biological_process|,molecular_function|,10,0.3,1.39,10,0.2,0.143,0.2,1.38,1.38,0.274,0,0,-0.8,1.6
ENSMUSG00000042742,B630005N14RIK,RIKEN cDNA B630005N14 gene,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,-0.7,1.36,9,-0.4,0.176,-0.4,1.38,-1.38,0.274,0,0,-2,0.4
ENSMUSG00000026222,SP100,nuclear antigen Sp100,nucleus|cytoplasm|PML body|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|protein binding|metal ion binding|,10,0.1,0.189,10,-0.5,3.84,-0.5,1.37,-1.37,0.275,0,0,-1.8,0.5
ENSMUSG00000032300,1700017B05RIK,RIKEN cDNA 1700017B05 gene,cytoplasm|,biological_process|,molecular_function|,10,0.3,2.51,10,0,0,0.3,1.37,1.37,0.275,0,0,-0.9,1.6
ENSMUSG00000020592,SDC1,syndecan 1,extracellular region|cytoplasm|focal adhesion|external side of plasma membrane|cell surface|membrane|integral component of membrane|protein complex|extracellular vesicular exosome|,inflammatory response|myoblast development|canonical Wnt signaling pathway|,glycoprotein binding|protein C-terminus binding|cytoskeletal protein binding|,10,-0.2,1.1,10,-0.2,0.39,-0.2,1.37,-1.37,0.275,0,0,-1.4,1.3
ENSMUSG00000050786,CCDC126,coiled-coil domain containing 126,extracellular region|membrane|,protein N-linked glycosylation|biological_process|,"molecular_function|alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity|",10,0,0,10,-0.5,3.15,-0.3,1.36,-1.36,0.277,0,0,-1.8,0.5
ENSMUSG00000002428,HLTF,helicase-like transcription factor,nucleus|cytoplasm|membrane|,"ATP catabolic process|transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|metabolic process|chromatin modification|","nucleotide binding|nucleic acid binding|DNA binding|catalytic activity|helicase activity|ATP binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|ligase activity|ATPase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|poly(A) RNA binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.5,2.63,10,0,0,-0.4,1.31,-1.31,0.285,0,0,-1.7,0.8
ENSMUSG00000040113,METTL11B,methyltransferase like 11B,cellular_component|nucleus|,biological_process|methylation|,molecular_function|methyltransferase activity|transferase activity|,10,0.2,1.55,10,0.1,0.0807,0.2,1.31,1.31,0.285,0,0,-0.9,1.7
ENSMUSG00000036941,ELAC1,elaC homolog 1 (E. coli),nucleus|cytoplasm|cytosol|,tRNA processing|tRNA 3'-trailer cleavage|,"nuclease activity|endonuclease activity|hydrolase activity|endoribonuclease activity, producing 5'-phosphomonoesters|metal ion binding|",10,0.1,0.128,10,0.2,1.36,0.2,1.3,1.3,0.287,0,0,-0.9,1.7
ENSMUSG00000035530,EIF1,eukaryotic translation initiation factor 1,cellular_component|,translation|translational initiation|dosage compensation by inactivation of X chromosome|,molecular_function|translation initiation factor activity|,10,0.4,1.15,10,0.2,0.441,0.3,1.29,1.29,0.289,0,0,-1.2,1.8
ENSMUSG00000014763,FAM120B,"family with sequence similarity 120, member B",nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell differentiation|",None,10,0.5,0.798,10,-0.8,0.881,0.5,1.28,1.28,0.291,0,0,-1.5,1.4
ENSMUSG00000063236,1110038F14RIK,RIKEN cDNA 1110038F14 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,3.21,10,-0.3,1.66,0.4,1.28,1.28,0.291,0,0,-1,1.6
ENSMUSG00000037095,LRG1,leucine-rich alpha-2-glycoprotein 1,extracellular space|extracellular space|extracellular vesicular exosome|,positive regulation of endothelial cell proliferation|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of angiogenesis|brown fat cell differentiation|,transforming growth factor beta receptor binding|,10,0.4,1.33,10,0.1,0.306,0.4,1.28,1.28,0.291,0,0,-0.7,1.8
ENSMUSG00000031984,2810004N23RIK,RIKEN cDNA 2810004N23 gene,cellular_component|,biological_process|,poly(A) RNA binding|,10,0.1,0.0995,10,0.4,2.28,0.3,1.26,1.26,0.294,0,0,-1,1.7
ENSMUSG00000026227,2810459M11RIK,RIKEN cDNA 2810459M11 gene,cellular_component|,biological_process|,protein binding|,10,0.2,1.56,10,0.1,0.057,0.2,1.24,1.24,0.298,0,0,-2,0.9
ENSMUSG00000057176,GM166,predicted gene 166,cellular_component|,biological_process|,molecular_function|,10,0.3,1.39,10,0.1,0.244,0.3,1.24,1.24,0.298,0,0,-0.5,2
ENSMUSG00000002006,PDZD4,PDZ domain containing 4,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,-0.3,0.321,10,-0.4,1.09,-0.3,1.24,-1.24,0.298,0,0,-1.5,1.1
ENSMUSG00000072849,SERPINA1E,"serine (or cysteine) peptidase inhibitor, clade A, member 1E",extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,glycoprotein binding|protease binding|endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|identical protein binding|,10,0.2,0.884,10,0.5,1.38,0.4,1.24,1.24,0.298,0,0,-0.4,2
ENSMUSG00000041722,KHDC1C,KH domain containing 1C,cellular_component|,biological_process|,molecular_function|RNA binding|,2,0.1,0.0123,2,-0.4,2.01,-0.4,1.24,-1.24,0.298,0,0,-2,1.5
ENSMUSG00000044165,BCL2L15,BCLl2-like 15,nucleus|cytosol|,biological_process|,molecular_function|,10,0.3,1.63,10,0,0,0.2,1.23,1.23,0.3,0,0,-1.8,1.2
ENSMUSG00000039330,TSGA10IP,testis specific 10 interacting protein,cellular_component|,biological_process|,molecular_function|,10,-0.3,2.16,10,0,0,-0.2,1.23,-1.23,0.3,0,0,-1.6,0.9
ENSMUSG00000017009,SDC4,syndecan 4,extracellular region|focal adhesion|cell surface|cell surface|membrane|integral component of membrane|costamere|membrane raft|extracellular vesicular exosome|,signal transduction|positive regulation of protein kinase activity|positive regulation of stress fiber assembly|positive regulation of focal adhesion assembly|,fibronectin binding|protein kinase C binding|cytoskeletal protein binding|thrombospondin receptor activity|,9,0.2,0.844,10,0.3,0.549,0.2,1.22,1.22,0.302,0,0,-0.9,1.7
ENSMUSG00000024114,PRSS41,"protease, serine 41",plasma membrane|membrane|anchored component of membrane|intracellular organelle|,proteolysis|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.2,0.675,10,0.2,0.649,0.2,1.22,1.22,0.302,0,0,-0.5,2
ENSMUSG00000026319,2310035C23RIK,RIKEN cDNA 2310035C23 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.4,3.28,-0.3,1.22,-1.22,0.302,0,0,-1.7,0.7
ENSMUSG00000021482,AAED1,AhpC/TSA antioxidant enzyme domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.5,0.905,10,0.3,0.703,0.4,1.2,1.2,0.306,0,0,-0.6,1.8
ENSMUSG00000020309,CHAC2,"ChaC, cation transport regulator 2",cellular_component|,biological_process|,molecular_function|,10,0,0,10,1,2.96,0.2,1.19,1.19,0.307,0,0,-0.3,2
ENSMUSG00000095098,CCDC85B,coiled-coil domain containing 85B,nucleus|nucleus|cytoplasm|centrosome|cytoskeleton|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell differentiation|negative regulation of cell growth|regulation of growth|negative regulation of fat cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",protein binding|,10,0,0,10,0.3,2.5,0.2,1.19,1.19,0.307,0,0,-0.7,1.8
ENSMUSG00000028409,SMU1,smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans),cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,9,0,0,8,-0.3,1.54,-0.2,1.19,-1.19,0.307,0,0,-1.9,1
ENSMUSG00000027834,SERPINI1,"serine (or cysteine) peptidase inhibitor, clade I, member 1",extracellular region|extracellular space|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of cell adhesion|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.2,1,10,0.3,0.381,0.2,1.18,1.18,0.309,0,0,-1.1,1.5
ENSMUSG00000025573,6030468B19RIK,RIKEN cDNA 6030468B19 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.1,0.0742,10,-0.5,2.58,-0.2,1.18,-1.18,0.309,0,0,-1.6,1
ENSMUSG00000067872,CCDC87,coiled-coil domain containing 87,cellular_component|,microtubule cytoskeleton organization|cytokinesis|biological_process|,molecular_function|microtubule binding|,10,0.5,2.2,10,0,0,0.2,1.16,1.16,0.314,0,0,-0.5,1.9
ENSMUSG00000041308,SNTB2,"syntrophin, basic 2",cytoplasm|cytoskeleton|microtubule|membrane|cell junction|cytoplasmic vesicle|protein complex|synapse|extracellular vesicular exosome|,None,actin binding|protein binding|calmodulin binding|poly(A) RNA binding|,10,0.5,2.67,10,0,0,0.3,1.15,1.15,0.316,0,0,-0.6,1.8
ENSMUSG00000025020,SLIT1,slit homolog 1 (Drosophila),extracellular region|extracellular space|extracellular space|cell|,multicellular organismal development|nervous system development|axonogenesis|axonogenesis|axon guidance|axon guidance|axon guidance|motor neuron axon guidance|olfactory bulb development|tangential migration from the subventricular zone to the olfactory bulb|telencephalon cell migration|cell differentiation|retinal ganglion cell axon guidance|retinal ganglion cell axon guidance|dorsal/ventral axon guidance|establishment of nucleus localization|neuron projection morphogenesis|negative regulation of axon extension involved in axon guidance|axon extension involved in axon guidance|negative chemotaxis|negative chemotaxis|,receptor binding|calcium ion binding|heparan sulfate proteoglycan binding|Roundabout binding|Roundabout binding|,9,0.1,0.287,9,-0.3,2.42,-0.3,1.14,-1.14,0.318,0,0,-1.4,1.4
ENSMUSG00000026085,LYG1,lysozyme G-like 1,cellular_component|extracellular region|,biological_process|metabolic process|peptidoglycan catabolic process|cell wall macromolecule catabolic process|,"molecular_function|lysozyme activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,0,0,10,-0.6,3.83,-0.6,1.14,-1.14,0.318,0,0,-2,0.6
ENSMUSG00000020441,2310033P09RIK,RIKEN cDNA 2310033P09 gene,cellular_component|,biological_process|,poly(A) RNA binding|,10,-0.2,1.33,10,-0.1,0.175,-0.2,1.14,-1.14,0.318,0,0,-1.4,1.3
ENSMUSG00000030822,PRR14,proline rich 14,cellular_component|,biological_process|,molecular_function|,10,0.3,1.36,10,0,0,0.3,1.13,1.13,0.319,0,0,-0.8,1.7
ENSMUSG00000024663,RAB3IL1,RAB3A interacting protein (rabin3)-like 1,cellular_component|,transport|protein transport|positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|kinase binding|,10,0.1,0.531,10,0.2,0.722,0.2,1.12,1.12,0.321,0,0,-0.5,2
ENSMUSG00000022351,SQLE,squalene epoxidase,endoplasmic reticulum|membrane|integral component of membrane|intracellular membrane-bounded organelle|,cellular aromatic compound metabolic process|metabolic process|cholesterol metabolic process|response to organic substance|oxidation-reduction process|,squalene monooxygenase activity|oxidoreductase activity|flavin adenine dinucleotide binding|,10,0.3,0.832,10,0.1,0.463,0.2,1.12,1.12,0.321,0,0,-0.9,1.7
ENSMUSG00000060268,GM1661,predicted gene 1661,cellular_component|,biological_process|,molecular_function|,10,0.7,1.97,10,0.2,0.171,0.5,1.11,1.11,0.323,0,0,-0.4,1.9
ENSMUSG00000025193,CUTC,cutC copper transporter homolog (E.coli),nucleus|nucleolus|cytoplasm|,protein tetramerization|copper ion homeostasis|,copper ion binding|metal ion binding|,10,0.2,0.7,10,0.2,0.512,0.2,1.11,1.11,0.323,0,0,-0.9,1.6
ENSMUSG00000039316,RFTN1,raftlin lipid raft linker 1,intracellular|cell|cytoplasm|endosome|plasma membrane|membrane|protein complex|membrane raft|extracellular vesicular exosome|,membrane raft assembly|T cell antigen processing and presentation|protein transport into membrane raft|interleukin-17 production|dsRNA transport|toll-like receptor 3 signaling pathway|growth|response to exogenous dsRNA|T cell receptor signaling pathway|B cell receptor signaling pathway|protein localization to membrane raft|,double-stranded RNA binding|,10,0,0,10,0.3,2.44,0.2,1.09,1.09,0.328,0,0,-0.4,2
ENSMUSG00000035439,HAUS8,"4HAUS augmin-like complex, subunit 8",cytoplasm|centrosome|cytoskeleton|microtubule|HAUS complex|,cell cycle|mitotic nuclear division|spindle assembly|centrosome organization|cell division|,molecular_function|,10,0.3,1.58,10,-0.2,0.0385,0.3,1.09,1.09,0.328,0,0,-1.1,1.6
ENSMUSG00000026915,STRBP,spermatid perinuclear RNA binding protein,nucleus|cytoplasm|cytoskeleton|microtubule cytoskeleton|,cellular component movement|multicellular organismal development|spermatogenesis|spermatid development|mechanosensory behavior|cell differentiation|,RNA binding|double-stranded RNA binding|single-stranded RNA binding|poly(A) RNA binding|,10,0,0,10,0.7,3.44,0.3,1.09,1.09,0.328,0,0,-0.5,1.8
ENSMUSG00000047515,BC049715,cDNA sequence BC049715,cellular_component|,biological_process|,molecular_function|,10,0.2,0.918,10,0.1,0.279,0.2,1.09,1.09,0.328,0,0,-0.8,1.8
ENSMUSG00000076431,SOX4,SRY (sex determining region Y)-box 4,nucleus|nucleus|cytoplasm|mitochondrion|nuclear transcription factor complex|,"skeletal system development|response to hypoxia|neural tube formation|pro-B cell differentiation|mitral valve morphogenesis|cardiac ventricle formation|cardiac right ventricle morphogenesis|atrial septum primum morphogenesis|noradrenergic neuron differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|heart development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|glial cell proliferation|spinal cord development|spinal cord motor neuron differentiation|glial cell development|positive regulation of Wnt signaling pathway|T cell differentiation|endocrine pancreas development|negative regulation of protein ubiquitination|regulation of protein stability|positive regulation of insulin secretion|somatic stem cell maintenance|ascending aorta morphogenesis|glucose homeostasis|DNA damage response, detection of DNA damage|positive regulation of apoptotic process|positive regulation of translation|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of protein export from nucleus|sympathetic nervous system development|protein stabilization|protein stabilization|canonical Wnt signaling pathway|limb bud formation|ventricular septum morphogenesis|negative regulation of cell death|neuroepithelial cell differentiation|kidney morphogenesis|cellular response to glucose stimulus|positive regulation of canonical Wnt signaling pathway|positive regulation of N-terminal peptidyl-lysine acetylation|",transcription regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|core promoter sequence-specific DNA binding|core promoter sequence-specific DNA binding|nucleic acid binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription coactivator activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein heterodimerization activity|,10,-0.3,1.26,10,-0.1,0.0107,-0.2,1.08,-1.08,0.33,0,0,-1.7,0.9
ENSMUSG00000022099,DMTN,dematin actin binding protein,intracellular|cell|cytoplasm|cytosol|cytosol|cytoskeleton|actin filament|plasma membrane|spectrin-associated cytoskeleton|membrane|cytoplasmic membrane-bounded vesicle|cortical cytoskeleton|platelet dense tubular network membrane|cell projection membrane|cell projection|perinuclear region of cytoplasm|,protein complex assembly|protein complex assembly|cytoskeleton organization|regulation of cell shape|regulation of cell shape|regulation of cell shape|regulation of lamellipodium assembly|positive regulation of fibroblast migration|negative regulation of peptidyl-threonine phosphorylation|negative regulation of cell-substrate adhesion|actin cytoskeleton organization|positive regulation of blood coagulation|regulation of actin cytoskeleton organization|negative regulation of peptidyl-serine phosphorylation|calcium-mediated signaling using intracellular calcium source|calcium-mediated signaling using extracellular calcium source|erythrocyte development|negative regulation of peptidyl-tyrosine phosphorylation|actin filament bundle assembly|regulation of filopodium assembly|actin filament capping|negative regulation of focal adhesion assembly|protein secretion by platelet|cellular response to calcium ion|cellular response to cAMP|positive regulation of wound healing|negative regulation of protein targeting to membrane|actin filament reorganization|negative regulation of substrate adhesion-dependent cell spreading|positive regulation of substrate adhesion-dependent cell spreading|positive regulation of platelet aggregation|positive regulation of integrin-mediated signaling pathway|,actin binding|receptor binding|spectrin binding|protein self-association|protein self-association|,10,-0.3,1.83,10,0.6,0.84,-0.2,1.07,-1.07,0.332,0,0,-0.9,1.7
ENSMUSG00000013707,TNFAIP8L2,"tumor necrosis factor, alpha-induced protein 8-like 2",cytoplasm|,immune system process|innate immune response|negative regulation of inflammatory response|negative regulation of T cell activation|,protein binding|,10,0,0,10,-0.6,2.1,-0.6,1.05,-1.05,0.336,0,0,-1.8,0.7
ENSMUSG00000071324,ARMC2,armadillo repeat containing 2,cellular_component|,biological_process|,molecular_function|,10,0.9,0.608,10,0.2,0.639,0.2,1.04,1.04,0.338,0,0,-0.6,2
ENSMUSG00000035578,IQCG,IQ motif containing G,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.6,1.76,10,0,0,0.2,1.04,1.04,0.338,0,0,-1.7,1
ENSMUSG00000079511,CCDC142,coiled-coil domain containing 142,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.238,10,-0.2,0.937,-0.2,1.04,-1.04,0.338,0,0,-1.8,0.8
ENSMUSG00000062393,DGKK,diacylglycerol kinase kappa,intracellular|plasma membrane|,response to oxidative stress|phosphorylation|intracellular signal transduction|diacylglycerol metabolic process|,nucleotide binding|diacylglycerol kinase activity|ATP binding|kinase activity|transferase activity|metal ion binding|,10,-0.3,1.19,10,0.4,1.57,0.4,1.03,1.03,0.34,0,0,-1.2,1.5
ENSMUSG00000022749,TBC1D23,"TBC1 domain family, member 23",cellular_component|,regulation of Rab GTPase activity|regulation of tumor necrosis factor production|positive regulation of interleukin-6 production|regulation of inflammatory response|,molecular_function|Rab GTPase activator activity|,10,0.3,1.12,10,0.1,0.216,0.2,1.03,1.03,0.34,0,0,-1.1,1.8
ENSMUSG00000041057,WDR43,WD repeat domain 43,cellular_component|nucleus|,biological_process|,poly(A) RNA binding|,8,-0.9,1.29,5,0.3,0.883,0.6,1.03,1.03,0.34,0,0,-1.7,1.7
ENSMUSG00000045827,SERPINB9,"serine (or cysteine) peptidase inhibitor, clade B, member 9",extracellular space|nucleus|cytoplasm|cytoplasm|cytosol|membrane|extracellular vesicular exosome|,T cell mediated cytotoxicity|acute inflammatory response to antigenic stimulus|immune response|negative regulation of endopeptidase activity|regulation of proteolysis|defense response to bacterium|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of T cell apoptotic process|,protease binding|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|protein binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|,10,0.1,0.156,10,0.4,1.19,0.2,1.03,1.03,0.34,0,0,-0.6,1.8
ENSMUSG00000058407,TXNDC9,thioredoxin domain containing 9,nucleus|cytoplasm|centrosome|midbody|,biological_process|cell redox homeostasis|,molecular_function|,10,-0.1,0.12,10,0.5,1.62,0.2,1.02,1.02,0.342,0,0,-1,1.7
ENSMUSG00000024395,LIMS2,LIM and senescent cell antigen like domains 2,plasma membrane|focal adhesion|membrane|cell junction|,single organismal cell-cell adhesion|negative regulation of apoptotic process|cell-cell junction organization|negative regulation of epithelial cell proliferation|negative regulation of neural precursor cell proliferation|negative regulation of hepatocyte proliferation|positive regulation of integrin-mediated signaling pathway|,molecular_function|zinc ion binding|metal ion binding|,10,-0.2,0.944,10,-0.1,0.204,-0.2,1.02,-1.02,0.342,0,0,-1.5,1.2
ENSMUSG00000027589,PCMTD2,protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2,cellular_component|cytoplasm|,cellular protein modification process|biological_process|,molecular_function|protein-L-isoaspartate (D-aspartate) O-methyltransferase activity|,10,0,0,10,0.4,1.82,0.3,0.998,0.998,0.347,0,0,-0.6,1.8
ENSMUSG00000047361,GM973,predicted gene 973,cellular_component|,biological_process|,molecular_function|,9,-0.5,0.734,9,0.4,2.36,0.3,0.996,0.996,0.347,0,0,-1.5,1.4
ENSMUSG00000048581,E130311K13RIK,RIKEN cDNA E130311K13 gene,extracellular space|membrane|integral component of membrane|,regulation of sequence-specific DNA binding transcription factor activity|negative regulation of ERK1 and ERK2 cascade|,"molecular_function|nucleic acid binding|hydrolase activity, acting on ester bonds|",10,-0.3,0.561,10,-0.2,0.554,-0.2,0.988,-0.988,0.349,0,0,-1.5,1.1
ENSMUSG00000028218,FAM92A,"family with sequence similarity 92, member A",cellular_component|,biological_process|,protein binding|,10,-0.1,0.255,10,-0.3,0.936,-0.2,0.985,-0.985,0.35,0,0,-1.5,1.2
ENSMUSG00000002664,PSPN,persephin,extracellular region|extracellular space|,branching involved in ureteric bud morphogenesis|,receptor binding|growth factor activity|,10,0.2,0.405,10,0.2,0.662,0.2,0.981,0.981,0.351,0,0,-0.7,1.8
ENSMUSG00000027233,PATL2,protein associated with topoisomerase II homolog 2 (yeast),cytoplasmic mRNA processing body|cytoplasmic mRNA processing body|nucleus|cytoplasm|cytoplasm|,negative regulation of cytoplasmic mRNA processing body assembly|negative regulation of cytoplasmic mRNA processing body assembly|negative regulation of translation|,G-quadruplex RNA binding|RNA binding|poly(U) RNA binding|translation repressor activity|poly(G) binding|,10,-0.1,0.291,10,1.6,3.73,1.6,0.957,0.957,0.357,0,0,-0.3,3
ENSMUSG00000052812,ATAD2B,"ATPase family, AAA domain containing 2B",nucleus|,biological_process|,nucleotide binding|ATP binding|lysine-acetylated histone binding|,10,-0.3,2.01,9,0,0,-0.2,0.944,-0.944,0.359,0,0,-1.7,1
ENSMUSG00000048546,TOB2,"transducer of ERBB2, 2",None,regulation of gene expression|negative regulation of osteoclast differentiation|positive regulation of ossification|,vitamin D receptor binding|,10,0.4,0.831,10,0.2,0.37,0.4,0.935,0.935,0.362,0,0,-0.7,1.8
ENSMUSG00000022151,TTC33,tetratricopeptide repeat domain 33,cellular_component|,biological_process|,molecular_function|,10,1,1.45,10,0.2,0.171,0.3,0.934,0.934,0.362,0,0,-0.7,2
ENSMUSG00000030966,TRIM21,tripartite motif-containing 21,intracellular|nucleus|cytoplasm|cytoplasm|SCF ubiquitin ligase complex|ribonucleoprotein complex|,protein polyubiquitination|protein monoubiquitination|cell cycle|protein ubiquitination|protein destabilization|negative regulation of NF-kappaB transcription factor activity|negative regulation of viral transcription|innate immune response|positive regulation of cell cycle|positive regulation of viral entry into host cell|positive regulation of sequence-specific DNA binding transcription factor activity|protein autoubiquitination|protein trimerization|negative regulation of protein deubiquitination|negative regulation of viral release from host cell|,"DNA binding|RNA binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.2,1.62,10,0,0,0.2,0.932,0.932,0.362,0,0,-1.1,1.6
ENSMUSG00000032726,BMP8A,bone morphogenetic protein 8a,extracellular region|extracellular space|,ossification|osteoblast differentiation|diet induced thermogenesis|transforming growth factor beta receptor signaling pathway|multicellular organismal development|germ cell development|spermatogenesis|cell differentiation|growth|negative regulation of insulin secretion|cartilage development|regulation of energy homeostasis|,cytokine activity|growth factor activity|,9,-0.1,0.135,9,-0.5,2.56,-0.4,0.926,-0.926,0.364,0,0,-1.7,1
ENSMUSG00000030321,EFCAB12,EF-hand calcium binding domain 12,cellular_component|,biological_process|,molecular_function|,10,0.2,0.185,10,0.3,0.84,0.2,0.925,0.925,0.364,0,0,-0.6,1.9
ENSMUSG00000052373,MPP3,"membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)",None,phosphorylation|,kinase activity|transferase activity|PDZ domain binding|,10,0.4,0.619,10,-0.3,2.48,-0.3,0.914,-0.914,0.367,0,0,-1.4,1.3
ENSMUSG00000054520,SH3BP2,SH3-domain binding protein 2,None,None,protein binding|SH3 domain binding|,10,0,0,10,0.3,1.25,0.3,0.913,0.913,0.367,0,0,-0.5,1.9
ENSMUSG00000037568,VASH2,vasohibin 2,cytoplasm|,positive regulation of endothelial cell proliferation|regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of angiogenesis|,molecular_function|,10,0.1,0.186,10,0.2,0.874,0.2,0.906,0.906,0.369,0,0,-1,1.8
ENSMUSG00000043789,VWCE,von Willebrand factor C and EGF domains,cellular_component|extracellular region|,biological_process|,calcium ion binding|,10,0.3,0.75,10,-0.4,2.66,-0.4,0.901,-0.901,0.37,0,0,-1.6,1.1
ENSMUSG00000029185,FAM114A1,"family with sequence similarity 114, member A1",cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.3,2.39,10,0,0,0.2,0.896,0.896,0.371,0,0,-1.1,1.6
ENSMUSG00000084957,BBIP1,BBSome interacting protein 1,cytoplasm|BBSome|,cilium assembly|eating behavior|receptor localization to nonmotile primary cilium|,molecular_function|,4,0,0,4,0.8,1.6,0.2,0.892,0.892,0.372,0,0,-1.1,2
ENSMUSG00000010538,TSACC,TSSK6 activating co-chaperone,cytoplasm|,negative regulation of protein kinase activity|positive regulation of protein kinase activity|,protein kinase inhibitor activity|protein kinase binding|Hsp70 protein binding|chaperone binding|,10,-0.4,2.16,10,0.2,0.301,-0.2,0.887,-0.887,0.374,0,0,-1.6,1
ENSMUSG00000043496,TRIL,TLR4 interactor with leucine-rich repeats,membrane|integral component of membrane|lipopolysaccharide receptor complex|,immune system process|regulation of cytokine production involved in immune response|inflammatory response|toll-like receptor 4 signaling pathway|innate immune response|,lipopolysaccharide binding|,8,0.8,0.0302,8,-0.4,1.99,-0.3,0.885,-0.885,0.374,0,0,-1.4,1.7
ENSMUSG00000024691,FAM111A,"family with sequence similarity 111, member A",chromatin|nucleus|cytoplasm|,DNA replication|negative regulation of viral genome replication|,molecular_function|catalytic activity|,10,0,0,10,0.3,2.01,0.2,0.877,0.877,0.376,0,0,-0.6,1.9
ENSMUSG00000028578,CAAP1,caspase activity and apoptosis inhibitor 1,cellular_component|,apoptotic process|biological_process|,molecular_function|,10,0.4,1.99,10,0,0,0.2,0.871,0.871,0.377,0,0,-0.7,1.8
ENSMUSG00000005357,SLC1A6,"solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6",Golgi apparatus|membrane|integral component of membrane|,transport|anion transport|dicarboxylic acid transport|L-glutamate transport|ion transmembrane transport|regulation of membrane potential|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|anion transmembrane transporter activity|symporter activity|sodium:dicarboxylate symporter activity|,10,-0.1,0.559,9,0.4,2.06,0.2,0.865,0.865,0.379,0,0,-0.6,2
ENSMUSG00000036097,FAM178A,"family with sequence similarity 178, member A",chromatin|extracellular space|nucleus|,biological_process|,molecular_function|,10,1.2,3.5,10,-0.1,0.00202,0.2,0.861,0.861,0.38,0,0,-0.3,2
ENSMUSG00000063253,SCOC,short coiled-coil protein,cytoplasm|endosome|Golgi apparatus|trans-Golgi network|membrane|,positive regulation of macroautophagy|,molecular_function|,10,0,0,10,0.3,2.47,0.2,0.854,0.854,0.381,0,0,-0.8,1.7
ENSMUSG00000024873,CNIH2,cornichon homolog 2 (Drosophila),endoplasmic reticulum|plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|dendrite|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|cell projection|dendritic spine|dendritic shaft|synapse|postsynaptic membrane|,"synaptic transmission, glutamatergic|intracellular signal transduction|regulation of membrane potential|localization within membrane|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|",channel regulator activity|,10,0.2,0.509,10,0.3,0.431,0.2,0.849,0.849,0.383,0,0,-1.1,1.5
ENSMUSG00000042694,OBFC1,oligonucleotide/oligosaccharide-binding fold containing 1,"chromosome, telomeric region|nuclear chromosome, telomeric region|nuclear chromosome, telomeric region|nucleus|nucleus|chromosome|intracellular membrane-bounded organelle|intermediate filament cytoskeleton|Stn1-Ten1 complex|",telomere maintenance|telomere maintenance via telomere lengthening|positive regulation of DNA replication|,nucleic acid binding|DNA binding|single-stranded DNA binding|protein binding|single-stranded telomeric DNA binding|,10,0.2,0.706,10,-0.3,0.877,0.3,0.849,0.849,0.383,0,0,-0.9,1.8
ENSMUSG00000091415,AK9,adenylate kinase 9,nucleus|cytoplasm|nuclear membrane|,dADP phosphorylation|dGDP phosphorylation|AMP phosphorylation|ADP phosphorylation|CDP phosphorylation|dAMP phosphorylation|CMP phosphorylation|dCMP phosphorylation|GDP phosphorylation|UDP phosphorylation|dCDP phosphorylation|TDP phosphorylation|,nucleoside diphosphate kinase activity|nucleoside phosphate kinase activity|,10,0,0,10,-0.3,2.28,-0.2,0.848,-0.848,0.383,0,0,-1.7,0.9
ENSMUSG00000030125,LRRC23,leucine rich repeat containing 23,cellular_component|,biological_process|,molecular_function|,10,0.1,0.168,10,0.4,1.2,0.2,0.83,0.83,0.388,0,0,-0.8,1.8
ENSMUSG00000050088,1600012H06RIK,RIKEN cDNA 1600012H06 gene,extracellular region|extracellular vesicular exosome|,apoptotic process|biological_process|,molecular_function|,10,0.2,0.456,10,0.8,0.516,0.2,0.829,0.829,0.388,0,0,-0.7,1.9
ENSMUSG00000004896,RRNAD1,ribosomal RNA adenine dimethylase domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,1.42,10,-0.2,0.352,0.2,0.829,0.829,0.388,0,0,-1.1,1.6
ENSMUSG00000031927,1700012B09RIK,RIKEN cDNA 1700012B09 gene,cellular_component|,biological_process|,molecular_function|,10,0.6,2.89,10,-0.2,0.729,0.2,0.826,0.826,0.389,0,0,-0.7,1.8
ENSMUSG00000006471,NDOR1,NADPH dependent diflavin oxidoreductase 1,nucleus|cytoplasm|cytosol|cytosol|intermediate filament cytoskeleton|,cell death|cellular response to menadione|oxidation-reduction process|oxidation-reduction process|,"NADPH-hemoprotein reductase activity|iron ion binding|FMN binding|oxidoreductase activity|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen|epoxide carboxylase activity|flavin adenine dinucleotide binding|NADP binding|reduced coenzyme F420:NADP+ oxidoreductase activity|",9,-0.3,1.23,9,0.4,0.083,-0.2,0.816,-0.816,0.391,0,0,-1.3,1.5
ENSMUSG00000042992,LOH12CR1,"loss of heterozygosity, 12, chromosomal region 1 homolog (human)",cellular_component|,biological_process|,molecular_function|,10,0.1,0.602,10,0.2,0.301,0.2,0.813,0.813,0.392,0,0,-0.4,2
ENSMUSG00000028439,FAM219A,"family with sequence similarity 219, member A",cellular_component|,biological_process|,molecular_function|,10,0.5,1.97,10,0,0,0.4,0.812,0.812,0.392,0,0,-1.3,1.6
ENSMUSG00000051285,PCMTD1,protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1,cellular_component|cytoplasm|,cellular protein modification process|biological_process|methylation|,molecular_function|protein-L-isoaspartate (D-aspartate) O-methyltransferase activity|methyltransferase activity|transferase activity|,10,0,0,10,-1.3,3.07,-0.2,0.81,-0.81,0.393,0,0,-2,0.6
ENSMUSG00000035864,SYT1,synaptotagmin I,cell|cytoplasm|plasma membrane|plasma membrane|synaptic vesicle|synaptic vesicle|synaptic vesicle|membrane|integral component of membrane|cell junction|secretory granule|secretory granule|synaptic vesicle membrane|dense core granule|SNARE complex|cytoplasmic vesicle|presynaptic membrane|neuron projection|intracellular organelle|synapse|excitatory synapse|,detection of calcium ion|transport|neurotransmitter secretion|synaptic vesicle exocytosis|regulation of calcium ion-dependent exocytosis|positive regulation of vesicle fusion|positive regulation of calcium ion-dependent exocytosis|vesicle docking|response to calcium ion|,"SNARE binding|phosphatidylserine binding|transporter activity|calcium ion binding|calcium ion binding|protein binding|calmodulin binding|phospholipid binding|calcium-dependent phospholipid binding|calcium-dependent phospholipid binding|phosphatidylinositol-4,5-bisphosphate binding|protein C-terminus binding|syntaxin-1 binding|syntaxin binding|clathrin binding|identical protein binding|metal ion binding|calcium-dependent protein binding|calcium-dependent protein binding|low-density lipoprotein particle receptor binding|",10,-0.2,0.821,10,-1.1,0.54,-0.2,0.808,-0.808,0.393,0,0,-2,0.5
ENSMUSG00000022913,PSMG1,"proteasome (prosome, macropain) assembly chaperone 1",nucleus|cytoplasm|endoplasmic reticulum|,cerebellar granule cell precursor proliferation|proteasome assembly|proteasome core complex assembly|,proteasome binding|,10,0.1,0.0171,10,-0.4,1.57,-0.3,0.807,-0.807,0.393,0,0,-1.3,1.8
ENSMUSG00000024534,SNCAIP,"synuclein, alpha interacting protein (synphilin)",cytoplasm|,dopamine metabolic process|regulation of neurotransmitter secretion|regulation of inclusion body assembly|,ubiquitin protein ligase binding|identical protein binding|,10,-0.3,0.676,10,-0.1,0.278,-0.2,0.803,-0.803,0.394,0,0,-1.8,0.7
ENSMUSG00000034917,TJP3,tight junction protein 3,nucleus|plasma membrane|tight junction|tight junction|cell surface|membrane|apical plasma membrane|cell junction|,regulation of G1/S transition of mitotic cell cycle|,protein binding|,10,0.5,1.86,10,0.1,0.369,0.2,0.8,0.8,0.395,0,0,-0.5,1.9
ENSMUSG00000021179,NRDE2,"nrde-2 necessary for RNA interference, domain containing",cellular_component|,biological_process|,molecular_function|,10,0.3,0.547,10,0.2,0.33,0.2,0.793,0.793,0.397,0,0,-0.8,1.7
ENSMUSG00000036925,SPT1,salivary protein 1,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.3,0.0117,10,0.3,0.841,0.3,0.788,0.788,0.398,0,0,-1.3,1.5
ENSMUSG00000039069,MTG2,mitochondrial ribosome associated GTPase 2,mitochondrion|mitochondrial inner membrane|mitochondrial matrix|mitochondrial ribosome|,GTP catabolic process|regulation of respiratory system process|regulation of mitochondrial translation|,nucleotide binding|GTPase activity|GTP binding|,10,0.5,1.97,10,0,0,0.4,0.787,0.787,0.398,0,0,-0.7,1.8
ENSMUSG00000050635,SPRR2F,small proline-rich protein 2F,cornified envelope|nucleus|cytoplasm|,epidermis development|keratinocyte differentiation|keratinization|response to estradiol|,molecular_function|,10,-0.2,1.45,10,0.4,1.03,-0.2,0.787,-0.787,0.398,0,0,-1.4,1.4
ENSMUSG00000004040,STAT3,signal transducer and activator of transcription 3,intracellular|nucleus|nucleus|cytoplasm|cytoplasm|mitochondrial inner membrane|plasma membrane|,"temperature homeostasis|eye photoreceptor cell differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein import into nucleus|acute-phase response|signal transduction|JAK-STAT cascade|cell proliferation|negative regulation of cell proliferation|phosphorylation|cytokine-mediated signaling pathway|stem cell maintenance|sexual reproduction|intracellular receptor signaling pathway|response to estradiol|cellular response to hormone stimulus|response to cytokine|regulation of multicellular organism growth|glucose homeostasis|eating behavior|positive regulation of Notch signaling pathway|negative regulation of glycolytic process|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|astrocyte differentiation|radial glial cell differentiation|growth hormone receptor signaling pathway|JAK-STAT cascade involved in growth hormone signaling pathway|JAK-STAT cascade involved in growth hormone signaling pathway|negative regulation of cell death|interleukin-6-mediated signaling pathway|negative regulation of neuron migration|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II repressing transcription factor binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|calcium ion binding|protein binding|transcription factor binding|protein kinase binding|protein phosphatase binding|CCR5 chemokine receptor binding|glucocorticoid receptor binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein dimerization activity|,10,0.1,0.058,10,0.3,1.16,0.2,0.786,0.786,0.398,0,0,-0.4,2
ENSMUSG00000033735,SPR,sepiapterin reductase,nucleus|cytoplasm|mitochondrion|extracellular vesicular exosome|,L-phenylalanine metabolic process|tetrahydrobiopterin biosynthetic process|nitric oxide biosynthetic process|metabolic process|response to organic substance|death|pteridine metabolic process|regulation of multicellular organism growth|norepinephrine metabolic process|dopamine metabolic process|serotonin metabolic process|tetrahydrobiopterin metabolic process|cell morphogenesis involved in neuron differentiation|voluntary musculoskeletal movement|oxidation-reduction process|,sepiapterin reductase activity|oxidoreductase activity|protein homodimerization activity|,9,-0.4,1.72,9,-0.1,0.0346,-0.2,0.775,-0.775,0.401,0,0,-1.8,0.9
ENSMUSG00000029094,AFAP1,actin filament associated protein 1,cytoplasm|cytoskeleton|actin filament|,regulation of signal transduction|,actin binding|SH3 domain binding|SH2 domain binding|,10,0.3,1.17,10,0.1,0.169,0.2,0.77,0.77,0.403,0,0,-0.8,1.8
ENSMUSG00000035901,DENND5A,DENN/MADD domain containing 5A,Golgi apparatus|membrane|,positive regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|protein binding|Rab guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Rab GTPase binding|,10,-0.1,0.047,10,0.5,1.91,0.5,0.768,0.768,0.403,0,0,-0.8,2
ENSMUSG00000039201,TBC1D25,"TBC1 domain family, member 25",cytoplasm|autophagic vacuole|cytoplasmic vesicle|,autophagy|regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|regulation of autophagic vacuole maturation|,GTPase activator activity|Rab GTPase activator activity|,10,-0.4,0.978,10,-0.2,0.177,-0.3,0.762,-0.762,0.405,0,0,-1.9,0.5
ENSMUSG00000026153,FAM135A,"family with sequence similarity 135, member A",cellular_component|,biological_process|,molecular_function|,10,-0.6,2.08,10,0.5,0.181,-0.3,0.755,-0.755,0.406,0,0,-1.8,1
ENSMUSG00000045410,AKR1E1,"aldo-keto reductase family 1, member E1",cytoplasm|extracellular vesicular exosome|,oxidation-reduction process|,"oxidoreductase activity|1,5-anhydro-D-fructose reductase activity|",9,0,0,9,0.3,1.24,0.3,0.755,0.755,0.406,0,0,-0.9,1.8
ENSMUSG00000036197,GXYLT1,glucoside xylosyltransferase 1,cellular_component|membrane|integral component of membrane|,O-glycan processing|,"transferase activity|transferase activity, transferring glycosyl groups|UDP-xylosyltransferase activity|",10,-0.1,0.155,10,-1.1,2.38,-0.2,0.742,-0.742,0.41,0,0,-2,0.5
ENSMUSG00000049515,ESPNL,espin-like,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.835,10,0.2,0.599,0.2,0.739,0.739,0.411,0,0,-1.3,1.5
ENSMUSG00000021904,SEMA3G,"sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G",extracellular region|membrane|extracellular vesicular exosome|,multicellular organismal development|,receptor activity|,10,0.4,0.963,10,0.1,0.0154,0.3,0.739,0.739,0.411,0,0,-0.8,1.8
ENSMUSG00000074121,NTF5,neurotrophin 5,extracellular region|,ganglion mother cell fate determination|long-term memory|sensory organ boundary specification|adult locomotory behavior|epidermis development|mechanoreceptor differentiation|innervation|negative regulation of cell death|taste bud development|,receptor binding|neurotrophin p75 receptor binding|growth factor activity|,10,1.2,3.52,10,-0.1,0.122,1.1,0.736,0.736,0.412,0,0,-0.7,2
ENSMUSG00000039599,FAM149B,"family with sequence similarity 149, member B",cellular_component|,biological_process|,molecular_function|,9,0.2,0.76,9,0.1,0.0775,0.2,0.735,0.735,0.412,0,0,-1.3,1.6
ENSMUSG00000030008,PRADC1,protease-associated domain containing 1,extracellular region|extracellular vesicular exosome|,biological_process|,molecular_function|,9,0.2,0.345,9,-0.2,1.01,-0.2,0.735,-0.735,0.412,0,0,-1.7,1.1
ENSMUSG00000062939,STAT4,signal transducer and activator of transcription 4,nucleus|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|protein phosphorylation|signal transduction|cell proliferation|cytokine-mediated signaling pathway|positive regulation of transcription from RNA polymerase II promoter|cellular response to organic substance|",DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|calcium ion binding|protein binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,0.2,1.41,10,0,0,0.2,0.735,0.735,0.412,0,0,-1.4,1.4
ENSMUSG00000070524,FCRLB,Fc receptor-like B,cytoplasm|endoplasmic reticulum|,negative regulation of immune response|,molecular_function|,10,1.2,1.01,10,0.2,0.684,0.2,0.734,0.734,0.413,0,0,-0.3,2
ENSMUSG00000070427,IL18BP,interleukin 18 binding protein,extracellular region|extracellular space|extracellular vesicular exosome|,T-helper 1 type immune response|,interleukin-18 binding|,10,0.3,0.326,10,0.3,0.472,0.3,0.732,0.732,0.413,0,0,-0.9,1.7
ENSMUSG00000022095,FAM160B2,"family with sequence similarity 160, member B2",cellular_component|,biological_process|,molecular_function|,10,-0.4,1.8,10,0.2,0.323,-0.1,0.728,-0.728,0.414,0,0,-1.4,1.5
ENSMUSG00000026767,FAM188A,"family with sequence similarity 188, member A",nucleus|,apoptotic process|biological_process|,molecular_function|calcium ion binding|,10,0.4,0.618,10,0.1,0.286,0.1,0.727,0.727,0.414,0,0,-0.8,1.9
ENSMUSG00000073436,EME2,essential meiotic endonuclease 1 homolog 2 (S. pombe),cellular_component|nucleus|,DNA repair|DNA recombination|cellular response to DNA damage stimulus|biological_process|,molecular_function|DNA binding|nuclease activity|endonuclease activity|hydrolase activity|,9,0.2,0.613,8,-0.2,1.21,-0.2,0.726,-0.726,0.415,0,0,-1.4,1.5
ENSMUSG00000072501,PHF20L1,PHD finger protein 20-like 1,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.1,0.164,10,0.2,0.665,0.2,0.724,0.724,0.415,0,0,-1,1.7
ENSMUSG00000027209,FAM227B,"family with sequence similarity 227, member B",cellular_component|,biological_process|,molecular_function|,9,-0.3,1.69,9,0.1,0.176,-0.3,0.719,-0.719,0.417,0,0,-1.8,1.2
ENSMUSG00000049313,SORL1,"sortilin-related receptor, LDLR class A repeats-containing",extracellular region|extracellular space|nuclear envelope lumen|endosome|early endosome|multivesicular body|endoplasmic reticulum|Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|Golgi cisterna|low-density lipoprotein particle|neuronal cell body|perinuclear region of cytoplasm|recycling endosome|extracellular vesicular exosome|,protein targeting to Golgi|protein targeting|protein targeting to lysosome|lipid metabolic process|transport|lipid transport|post-Golgi vesicle-mediated transport|endocytosis|multicellular organismal development|steroid metabolic process|cholesterol metabolic process|regulation of smooth muscle cell migration|cell migration|negative regulation of protein binding|negative regulation of protein oligomerization|protein retention in Golgi apparatus|positive regulation of protein catabolic process|protein maturation|positive regulation of protein exit from endoplasmic reticulum|negative regulation of beta-amyloid formation|positive regulation of ER to Golgi vesicle-mediated transport|positive regulation of early endosome to recycling endosome transport|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of protein localization to early endosome|positive regulation of endocytic recycling|,beta-amyloid binding|protein binding|low-density lipoprotein particle binding|ADP-ribosylation factor binding|,10,-0.2,0.716,10,0.2,0.44,-0.2,0.718,-0.718,0.417,0,0,-1.1,1.8
ENSMUSG00000017314,MPP2,"membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)",None,None,protein binding|PDZ domain binding|,10,0,0,10,-0.3,1.91,-0.2,0.711,-0.711,0.419,0,0,-1.4,1.3
ENSMUSG00000045767,B230219D22RIK,RIKEN cDNA B230219D22 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.955,-0.1,0.707,-0.707,0.42,0,0,-1.8,0.9
ENSMUSG00000001119,COL6A1,"collagen, type VI, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|lysosomal membrane|membrane|extracellular matrix|extracellular matrix|sarcolemma|protein complex|extracellular vesicular exosome|,osteoblast differentiation|cell adhesion|protein heterotrimerization|cellular response to amino acid stimulus|,platelet-derived growth factor binding|,10,1.3,1.98,10,-0.1,0.692,-0.1,0.698,-0.698,0.423,0,0,-0.8,2
ENSMUSG00000036395,GLB1L2,"galactosidase, beta 1-like 2",cellular_component|extracellular region|,carbohydrate metabolic process|metabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-galactosidase activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,-0.1,0.68,10,0.2,0.318,-0.2,0.696,-0.696,0.424,0,0,-1.6,1.1
ENSMUSG00000032184,LYSMD2,"LysM, putative peptidoglycan-binding, domain containing 2",cellular_component|,biological_process|,molecular_function|,10,0.3,0.397,10,0.2,0.421,0.2,0.69,0.69,0.426,0,0,-0.9,1.7
ENSMUSG00000017049,CCDC70,coiled-coil domain containing 70,extracellular region|plasma membrane|,biological_process|,molecular_function|,10,0,0,10,-0.5,1.74,-0.3,0.689,-0.689,0.426,0,0,-1.7,0.9
ENSMUSG00000055629,B4GALNT4,"beta-1,4-N-acetyl-galactosaminyl transferase 4",Golgi apparatus|membrane|integral component of membrane|Golgi cisterna membrane|,metabolic process|,acetylgalactosaminyltransferase activity|acetylgalactosaminyltransferase activity|transferase activity|N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity|,10,0.6,1.15,10,0.1,0.118,0.2,0.687,0.687,0.427,0,0,-0.6,1.9
ENSMUSG00000036820,AMDHD2,amidohydrolase domain containing 2,nucleus|,carbohydrate metabolic process|N-acetylglucosamine metabolic process|N-acetylneuraminate catabolic process|,"N-acetylglucosamine-6-phosphate deacetylase activity|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|metal ion binding|",10,0.4,2.07,10,-0.1,0.164,0.2,0.686,0.686,0.427,0,0,-1.1,1.6
ENSMUSG00000070424,ART5,ADP-ribosyltransferase 5,extracellular region|membrane|,protein ADP-ribosylation|,"NAD+ ADP-ribosyltransferase activity|NAD+ nucleosidase activity|NAD(P)+-protein-arginine ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.827,10,-0.3,0.564,0.1,0.684,0.684,0.428,0,0,-1.3,1.4
ENSMUSG00000042842,SERPINB6B,"serine (or cysteine) peptidase inhibitor, clade B, member 6b",intracellular|,gonad development|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|,10,-0.2,0.0627,10,-0.2,0.673,-0.2,0.678,-0.678,0.429,0,0,-1.6,1.3
ENSMUSG00000073791,EFCAB7,EF-hand calcium binding domain 7,cellular_component|,biological_process|,calcium ion binding|metal ion binding|,10,-0.2,0.595,10,1.4,1.67,-0.2,0.672,-0.672,0.431,0,0,-1.1,2.9
ENSMUSG00000044933,SSTR3,somatostatin receptor 3,cytoplasm|plasma membrane|cilium|membrane|integral component of membrane|nonmotile primary cilium|ciliary membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|somatostatin receptor activity|,10,0,0,10,0.4,1.96,0.2,0.667,0.667,0.432,0,0,-0.9,1.7
ENSMUSG00000049643,2310022A10RIK,RIKEN cDNA 2310022A10 gene,nucleus|,biological_process|,molecular_function|,9,0.7,1.4,9,-0.1,0.00939,0.2,0.666,0.666,0.433,0,0,-0.6,2
ENSMUSG00000054215,SPRR2K,small proline-rich protein 2K,cornified envelope|cytoplasm|,epidermis development|keratinocyte differentiation|keratinization|,molecular_function|,10,-0.1,0.314,10,-0.1,0.405,-0.1,0.659,-0.659,0.435,0,0,-1.4,1.5
ENSMUSG00000032640,CHSY1,chondroitin sulfate synthase 1,extracellular region|Golgi apparatus|membrane|membrane|integral component of membrane|Golgi cisterna membrane|,chondrocyte development|proximal/distal pattern formation|chondroitin sulfate biosynthetic process|chondroitin sulfate biosynthetic process|negative regulation of ossification|positive regulation of smoothened signaling pathway|cartilage development|sulfation|bone morphogenesis|,"acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity|",10,0.1,0.558,10,0.1,0.155,0.1,0.654,0.654,0.436,0,0,-1.1,1.7
ENSMUSG00000028626,COL9A2,"collagen, type IX, alpha 2",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type IX trimer|,None,None,10,-0.1,0.0724,10,0.2,0.742,0.2,0.644,0.644,0.439,0,0,-1.1,1.7
ENSMUSG00000058741,PRR19,proline rich 19,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,2.21,0.4,0.633,0.633,0.443,0,0,-0.5,2
ENSMUSG00000039963,CCDC40,coiled-coil domain containing 40,cytoplasm|cilium|cell projection|,heart looping|cilium movement|epithelial cilium movement|regulation of cilium beat frequency|lung development|lung development|determination of pancreatic left/right asymmetry|epithelial cilium movement involved in determination of left/right asymmetry|epithelial cilium movement involved in determination of left/right asymmetry|axonemal dynein complex assembly|determination of digestive tract left/right asymmetry|determination of liver left/right asymmetry|,molecular_function|,10,-0.7,0.764,10,0.1,0.192,0.2,0.632,0.632,0.443,0,0,-1.8,1.2
ENSMUSG00000033632,AW554918,expressed sequence AW554918,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.604,10,0.2,0.281,-0.1,0.627,-0.627,0.445,0,0,-1.6,1.2
ENSMUSG00000063160,NUMBL,numb-like,cytoplasm|,multicellular organismal development|nervous system development|neuroblast proliferation|axonogenesis|cytokine-mediated signaling pathway|protein metabolic process|lateral ventricle development|neuroblast division in subventricular zone|forebrain development|adherens junction organization|positive regulation of neurogenesis|positive regulation of dendrite morphogenesis|,None,10,0,0,10,0.5,2.76,0.4,0.621,0.621,0.447,0,0,-0.5,2
ENSMUSG00000078320,GM362,predicted gene 362,None,None,None,10,-0.2,0.931,10,0.1,0.132,-0.2,0.62,-0.62,0.447,0,0,-1.6,1.2
ENSMUSG00000060311,MUCL1,mucin-like 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.155,10,0.6,2.88,0.3,0.616,0.616,0.448,0,0,-0.6,1.9
ENSMUSG00000025916,PPP1R42,"protein phosphatase 1, regulatory subunit 42",manchette|cytoplasm|centrosome|microtubule organizing center|cytoskeleton|microtubule cytoskeleton|,regulation of phosphatase activity|,actin binding|protein binding|tubulin binding|dynein binding|,9,0.2,0.191,9,0.2,0.477,0.2,0.612,0.612,0.45,0,0,-0.9,1.9
ENSMUSG00000030729,PGM2L1,phosphoglucomutase 2-like 1,cytosol|,carbohydrate metabolic process|glucose metabolic process|phosphorylation|phosphorylation|,"transferase activity|isomerase activity|intramolecular transferase activity, phosphotransferases|glucose-1,6-bisphosphate synthase activity|glucose-1,6-bisphosphate synthase activity|",10,0.8,1.81,10,-0.2,0.227,0.2,0.609,0.609,0.451,0,0,-0.8,2
ENSMUSG00000032305,FAM219B,"family with sequence similarity 219, member B",cellular_component|,biological_process|,molecular_function|,10,-0.4,0.905,10,0.2,0.654,-0.3,0.6,-0.6,0.454,0,0,-1.8,1.1
ENSMUSG00000071724,SMPD5,sphingomyelin phosphodiesterase 5,mitochondrion|,ceramide metabolic process|,sphingomyelin phosphodiesterase activity|,10,0,0,10,0.4,1.89,0.3,0.596,0.596,0.455,0,0,-0.8,1.9
ENSMUSG00000025144,STRA13,stimulated by retinoic acid 13,"chromosome, centromeric region|kinetochore|nucleus|chromosome|Fanconi anaemia nuclear complex|FANCM-MHF complex|",resolution of meiotic recombination intermediates|DNA repair|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|replication fork processing|cell division|kinetochore assembly|,DNA binding|double-stranded DNA binding|,10,0.4,2.13,10,-0.1,0.0846,0.2,0.595,0.595,0.455,0,0,-1.4,1.5
ENSMUSG00000015962,1700016C15RIK,RIKEN cDNA 1700016C15 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,1.08,-0.2,0.592,-0.592,0.456,0,0,-1.7,1.1
ENSMUSG00000016998,SVS4,seminal vesicle secretory protein 4,extracellular region|,None,None,10,0.5,1.74,10,-0.1,0.339,0.2,0.587,0.587,0.458,0,0,-0.7,1.8
ENSMUSG00000022773,YPEL1,yippee-like 1 (Drosophila),cellular_component|nucleus|,biological_process|,molecular_function|,10,0.2,0.745,10,0.1,0.0815,0.1,0.585,0.585,0.458,0,0,-1.2,1.6
ENSMUSG00000038260,TRPM4,"transient receptor potential cation channel, subfamily M, member 4",endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|membrane|integral component of membrane|,immune system process|dendritic cell chemotaxis|regulation of T cell cytokine production|transport|ion transport|cation transport|calcium ion transport|positive regulation of cell proliferation|protein sumoylation|ion transmembrane transport|regulation of ion transmembrane transport|regulation of membrane potential|transmembrane transport|calcium ion transmembrane transport|positive regulation of canonical Wnt signaling pathway|,nucleotide binding|ion channel activity|calcium activated cation channel activity|calcium activated cation channel activity|calcium activated cation channel activity|voltage-gated ion channel activity|calcium channel activity|calmodulin binding|ATP binding|,10,0,0,10,0.5,1.37,0.3,0.585,0.585,0.458,0,0,-0.6,2
ENSMUSG00000026718,STAM,signal transducing adaptor molecule (SH3 domain and ITAM motif) 1,cytoplasm|endosome|membrane|,transport|intracellular protein transport|protein transport|,protein binding|,10,-0.3,1.78,10,0,0,-0.2,0.58,-0.58,0.46,0,0,-1.6,1.2
ENSMUSG00000019951,UHRF1BP1L,UHRF1 (ICBP90) binding protein 1-like,cellular_component|,biological_process|,molecular_function|,10,0.2,0.539,10,0.2,0.0892,0.2,0.577,0.577,0.461,0,0,-1.1,1.6
ENSMUSG00000051736,FAM229B,"family with sequence similarity 229, member B",cellular_component|,biological_process|,molecular_function|,10,0.1,0.202,10,0.4,0.837,0.2,0.575,0.575,0.462,0,0,-0.9,1.7
ENSMUSG00000047921,TRAPPC9,trafficking protein particle complex 9,cytoplasm|endoplasmic reticulum|Golgi apparatus|,cell differentiation|,None,10,0,0,10,0.2,0.933,0.1,0.574,0.574,0.462,0,0,-1,1.7
ENSMUSG00000095845,GM5741,predicted gene 5741,cellular_component|plasma membrane|membrane|,signal transduction|biological_process|,molecular_function|signal transducer activity|,10,0,0,10,0.3,2.04,0.3,0.572,0.572,0.463,0,0,-0.8,1.8
ENSMUSG00000025766,D3ERTD751E,"DNA segment, Chr 3, ERATO Doi 751, expressed",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.227,10,-0.2,0.516,-0.2,0.572,-0.572,0.463,0,0,-1.8,0.9
ENSMUSG00000002227,MOV10,Moloney leukemia virus 10,cytoplasmic mRNA processing body|extracellular space|cytoplasm|,gene silencing by RNA|mRNA cleavage involved in gene silencing by miRNA|,nucleotide binding|RNA binding|helicase activity|ATP binding|hydrolase activity|poly(A) RNA binding|,10,0.2,0.584,10,0.1,0.0578,0.2,0.569,0.569,0.464,0,0,-1.2,1.6
ENSMUSG00000037172,E330009J07RIK,RIKEN cDNA E330009J07 gene,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.921,10,0.3,0.26,-0.2,0.566,-0.566,0.465,0,0,-1.5,1.4
ENSMUSG00000041040,FAM117B,"family with sequence similarity 117, member B",cellular_component|,biological_process|,molecular_function|,10,-0.3,0.75,10,-0.1,0.222,-0.2,0.566,-0.566,0.465,0,0,-1.5,1.6
ENSMUSG00000029280,SMR3A,submaxillary gland androgen regulated protein 3A,extracellular region|,None,None,10,0.1,0.0932,10,0.2,0.788,0.1,0.554,0.554,0.469,0,0,-0.9,1.8
ENSMUSG00000078521,AUNIP,N/A,None,None,None,10,0.1,0.38,10,0.3,0.527,0.2,0.551,0.551,0.47,0,0,-1.4,1.4
ENSMUSG00000002274,METRN,"meteorin, glial cell differentiation regulator",extracellular region|extracellular space|,multicellular organismal development|nervous system development|glial cell differentiation|cell differentiation|positive regulation of axonogenesis|,molecular_function|,10,0,0,10,0.3,1.48,0.2,0.549,0.549,0.471,0,0,-0.9,1.8
ENSMUSG00000034379,WDR5B,WD repeat domain 5B,cellular_component|,biological_process|,molecular_function|,10,0.2,0.592,10,0.1,0.0507,0.1,0.548,0.548,0.471,0,0,-0.9,1.9
ENSMUSG00000037349,NUDT22,nudix (nucleoside diphosphate linked moiety X)-type motif 22,cellular_component|,biological_process|,molecular_function|hydrolase activity|,10,-0.4,1.71,10,0,0,-0.1,0.544,-0.544,0.473,0,0,-1.6,1.2
ENSMUSG00000031558,SLIT2,slit homolog 2 (Drosophila),extracellular region|extracellular space|extracellular space|cytoplasm|plasma membrane|cell surface|extracellular vesicular exosome|,metanephros development|ureteric bud development|in utero embryonic development|negative regulation of protein phosphorylation|cell migration involved in sprouting angiogenesis|negative regulation of leukocyte chemotaxis|chemotaxis|multicellular organismal development|nervous system development|axonogenesis|axonogenesis|axon guidance|axon guidance|axon guidance|axon guidance|motor neuron axon guidance|negative regulation of cell proliferation|negative regulation of lamellipodium assembly|negative regulation of endothelial cell migration|negative regulation of gene expression|negative regulation of smooth muscle cell migration|single organismal cell-cell adhesion|single organismal cell-cell adhesion|olfactory bulb development|chemorepulsion involved in postnatal olfactory bulb interneuron migration|corticospinal neuron axon guidance through spinal cord|telencephalon cell migration|cell differentiation|negative regulation of cell growth|negative regulation of cell migration|negative regulation of axon extension|negative regulation of actin filament polymerization|retinal ganglion cell axon guidance|retinal ganglion cell axon guidance|retinal ganglion cell axon guidance|dorsal/ventral axon guidance|dorsal/ventral axon guidance|Roundabout signaling pathway|positive regulation of apoptotic process|negative regulation of catalytic activity|negative regulation of vascular permeability|branching morphogenesis of an epithelial tube|neuron projection morphogenesis|neuron projection morphogenesis|axon extension involved in axon guidance|negative regulation of inflammatory response|negative chemotaxis|negative chemotaxis|induction of negative chemotaxis|negative regulation of small GTPase mediated signal transduction|mammary gland duct morphogenesis|mammary gland duct morphogenesis|mammary duct terminal end bud growth|negative regulation of chemokine-mediated signaling pathway|cellular response to heparin|negative regulation of smooth muscle cell chemotaxis|negative regulation of mononuclear cell migration|negative regulation of neutrophil chemotaxis|negative regulation of monocyte chemotaxis|negative regulation of retinal ganglion cell axon guidance|negative regulation of cellular response to growth factor stimulus|,GTPase inhibitor activity|receptor binding|calcium ion binding|protein binding|heparin binding|identical protein binding|protein homodimerization activity|laminin-1 binding|proteoglycan binding|heparan sulfate proteoglycan binding|chemorepellent activity|Roundabout binding|,8,0.1,0.384,8,0.1,0.208,0.1,0.542,0.542,0.474,0,0,-1.2,1.8
ENSMUSG00000055030,SPRR2E,small proline-rich protein 2E,cornified envelope|cytoplasm|,epidermis development|keratinocyte differentiation|keratinization|response to estradiol|,molecular_function|,10,0,0,10,-0.3,2.03,-0.3,0.531,-0.531,0.477,0,0,-1.7,1
ENSMUSG00000075705,MSRB1,methionine sulfoxide reductase B1,nucleus|cytoplasm|cytoskeleton|actin cytoskeleton|,immune system process|response to oxidative stress|actin filament polymerization|protein repair|innate immune response|oxidation-reduction process|,"actin binding|peptide-methionine (S)-S-oxide reductase activity|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor|peptide-methionine (R)-S-oxide reductase activity|metal ion binding|methionine-R-sulfoxide reductase activity|",10,0.1,0.508,10,0.1,0.067,0.1,0.528,0.528,0.478,0,0,-1.3,1.5
ENSMUSG00000036299,BC031181,cDNA sequence BC031181,cellular_component|,signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|,10,0.2,0.889,10,0,0,0.2,0.526,0.526,0.479,0,0,-1,1.7
ENSMUSG00000021275,TECPR2,tectonin beta-propeller repeat containing 2,cellular_component|,biological_process|,molecular_function|,9,0,0,9,-0.2,0.612,-0.1,0.526,-0.526,0.479,0,0,-1.6,1.4
ENSMUSG00000056737,CAPG,"capping protein (actin filament), gelsolin-like",extracellular region|nucleus|cytoplasm|nuclear membrane|extracellular vesicular exosome|,cell projection assembly|actin filament capping|,actin binding|,10,-0.1,0.0489,10,-0.2,0.565,-0.1,0.523,-0.523,0.48,0,0,-1.3,1.6
ENSMUSG00000034586,HID1,HID1 domain containing,Golgi trans cisterna|cytoplasm|Golgi apparatus|Golgi medial cisterna|cytoplasmic microtubule|membrane|extracellular vesicular exosome|extrinsic component of Golgi membrane|,intracellular protein transport|response to brefeldin A|,molecular_function|,10,0.1,0.505,10,0.1,0.0649,0.1,0.523,0.523,0.48,0,0,-1.6,1.3
ENSMUSG00000043541,CASC1,cancer susceptibility candidate 1,cytoplasmic microtubule|,microtubule-based movement|,microtubule binding|beta-tubulin binding|,10,0.3,1.33,10,-0.3,2.37,-0.2,0.521,-0.521,0.481,0,0,-1.8,1
ENSMUSG00000050628,UBALD2,UBA-like domain containing 2,cellular_component|,biological_process|,molecular_function|,8,0.1,0.215,8,1.3,1.42,0.5,0.52,0.52,0.481,0,0,-0.5,2
ENSMUSG00000031428,ZCCHC18,"zinc finger, CCHC domain containing 18",nuclear speck|,BMP signaling pathway|,nucleic acid binding|zinc ion binding|ligand-dependent nuclear receptor transcription coactivator activity|metal ion binding|,10,0.2,0.97,10,0,0,0.2,0.514,0.514,0.484,0,0,-1.1,1.7
ENSMUSG00000078784,1810022K09RIK,RIKEN cDNA 1810022K09 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.171,10,-0.2,0.552,-0.1,0.509,-0.509,0.486,0,0,-1.8,0.9
ENSMUSG00000054237,FRA10AC1,FRA10AC1 homolog (human),cellular_component|nucleus|,biological_process|,molecular_function|,10,0,0,10,0.3,1.01,0.1,0.507,0.507,0.486,0,0,-0.8,1.8
ENSMUSG00000096826,CCL27B,chemokine (C-C motif) ligand 27b,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,1.26,0.2,0.507,0.507,0.486,0,0,-0.9,1.7
ENSMUSG00000060568,FAM78B,"family with sequence similarity 78, member B",cellular_component|,biological_process|,molecular_function|,10,0.2,0.3,10,0.1,0.27,0.2,0.496,0.496,0.491,0,0,-0.6,2
ENSMUSG00000034848,TTC21B,tetratricopeptide repeat domain 21B,nuclear chromatin|intracellular|cell|cytoplasm|cytoskeleton|cilium|cilium|intraciliary transport particle A|intraciliary transport particle A|cell projection|,regulation of transcription from RNA polymerase II promoter|smoothened signaling pathway|regulation of smoothened signaling pathway|ventricular system development|forebrain dorsal/ventral pattern formation|intraciliary retrograde transport|intraciliary retrograde transport|intraciliary transport involved in cilium morphogenesis|cilium morphogenesis|,molecular_function|,10,0.1,0.0426,10,-0.3,1.55,-0.2,0.491,-0.491,0.493,0,0,-1.7,1.1
ENSMUSG00000059820,AU019823,expressed sequence AU019823,cellular_component|,biological_process|,molecular_function|,10,0.5,0.654,10,-0.3,1.31,-0.2,0.486,-0.486,0.495,0,0,-1.4,1.5
ENSMUSG00000062342,SERPINB9E,"serine (or cysteine) peptidase inhibitor, clade B, member 9e",cytoplasm|,negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|,10,0.2,0.753,10,0,0,0.1,0.484,0.484,0.495,0,0,-1.1,1.6
ENSMUSG00000046688,TIFA,TRAF-interacting protein with forkhead-associated domain,intracellular|,I-kappaB kinase/NF-kappaB signaling|,protein binding|,10,0.1,0.303,10,-0.7,1.35,0.1,0.479,0.479,0.497,0,0,-1.7,1.3
ENSMUSG00000028556,DOCK7,dedicator of cytokinesis 7,COP9 signalosome|cell projection|,microtubule cytoskeleton organization|hematopoietic progenitor cell differentiation|small GTPase mediated signal transduction|multicellular organismal development|nervous system development|axonogenesis|cell differentiation|neuron projection development|activation of Rac GTPase activity|positive regulation of peptidyl-serine phosphorylation|pigmentation|establishment of neuroblast polarity|,guanyl-nucleotide exchange factor activity|Rac GTPase binding|Rac GTPase binding|,10,-0.1,0.135,10,-0.2,0.418,-0.1,0.475,-0.475,0.499,0,0,-1.5,1.5
ENSMUSG00000019362,D8ERTD738E,"DNA segment, Chr 8, ERATO Doi 738, expressed",cellular_component|,biological_process|,molecular_function|,10,0.3,1.2,10,0,0,0.1,0.475,0.475,0.499,0,0,-1.4,1.6
ENSMUSG00000009115,SPATC1L,spermatogenesis and centriole associated 1 like,cellular_component|,biological_process|,molecular_function|,10,0.4,2.09,10,0,0,0.2,0.474,0.474,0.499,0,0,-1.1,1.7
ENSMUSG00000043807,LY6G5B,"lymphocyte antigen 6 complex, locus G5B",cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.1,0.196,10,0.2,0.367,0.1,0.472,0.472,0.5,0,0,-1.1,1.7
ENSMUSG00000090077,LIME1,Lck interacting transmembrane adaptor 1,extracellular space|plasma membrane|membrane|integral component of membrane|B cell receptor complex|,immune system process|regulation of transcription from RNA polymerase II promoter|regulation of phosphatidylinositol 3-kinase signaling|regulation of NF-kappaB import into nucleus|regulation of I-kappaB kinase/NF-kappaB signaling|regulation of MAP kinase activity|T cell receptor signaling pathway|B cell receptor signaling pathway|regulation of release of sequestered calcium ion into cytosol|,protein binding|protein kinase binding|,10,0.2,0.462,10,0.1,0.225,0.1,0.471,0.471,0.501,0,0,-1,1.8
ENSMUSG00000039031,ARHGAP18,Rho GTPase activating protein 18,intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,0.1,0.365,10,0.1,0.144,0.1,0.466,0.466,0.502,0,0,-1.5,1.4
ENSMUSG00000042208,0610010F05RIK,RIKEN cDNA 0610010F05 gene,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.551,9,0.7,0.945,-0.2,0.465,-0.465,0.503,0,0,-1.3,1.7
ENSMUSG00000047115,FAM221A,"family with sequence similarity 221, member A",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.103,10,-0.2,0.614,-0.1,0.464,-0.464,0.503,0,0,-1.7,1.1
ENSMUSG00000072568,FAM84B,"family with sequence similarity 84, member B",cytoplasm|plasma membrane|,biological_process|,molecular_function|,10,0.1,0.109,10,0.2,0.533,0.1,0.459,0.459,0.505,0,0,-0.8,2
ENSMUSG00000053617,SH3PXD2A,SH3 and PX domains 2A,podosome|cytoplasm|cell junction|cell projection|,superoxide metabolic process|reactive oxygen species metabolic process|,protein binding|phosphatidylinositol binding|,10,0,0,10,0.2,0.635,0.1,0.458,0.458,0.506,0,0,-1.3,1.6
ENSMUSG00000035671,ZSWIM4,zinc finger SWIM-type containing 4,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.3,1.47,10,-0.4,0.657,0.2,0.45,0.45,0.509,0,0,-1.5,1.4
ENSMUSG00000045659,PLEKHA7,"pleckstrin homology domain containing, family A member 7",cytoplasm|centrosome|cytoskeleton|zonula adherens|cell junction|extracellular vesicular exosome|,zonula adherens maintenance|epithelial cell-cell adhesion|,delta-catenin binding|,10,-0.1,0.0362,10,-0.2,0.556,-0.1,0.441,-0.441,0.512,0,0,-1.6,1.3
ENSMUSG00000068167,CSNKA2IP,"casein kinase 2, alpha prime interacting protein",nucleus|,biological_process|,protein binding|,10,0,0,10,-0.6,1.5,-0.2,0.439,-0.439,0.513,0,0,-1.9,0.7
ENSMUSG00000014782,PLEKHG4,"pleckstrin homology domain containing, family G (with RhoGef domain) member 4",cellular_component|,biological_process|,molecular_function|,10,0.1,0.332,10,0.1,0.147,0.1,0.438,0.438,0.514,0,0,-1.4,1.4
ENSMUSG00000041161,OTUD3,OTU domain containing 3,cellular_component|,proteolysis|protein K11-linked deubiquitination|protein K6-linked deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0,0,10,0.4,1.2,0.1,0.437,0.437,0.514,0,0,-0.6,2
ENSMUSG00000006574,SLC4A1,"solute carrier family 4 (anion exchanger), member 1",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|Z disc|cortical cytoskeleton|cortical cytoskeleton|extracellular vesicular exosome|blood microparticle|,transport|ion transport|anion transport|chloride transport|inorganic anion transport|bicarbonate transport|ion transmembrane transport|chloride transmembrane transport|,actin binding|transporter activity|inorganic anion exchanger activity|protein binding|protein C-terminus binding|anion transmembrane transporter activity|bicarbonate transmembrane transporter activity|chloride transmembrane transporter activity|anion:anion antiporter activity|ankyrin binding|protein homodimerization activity|,10,0,0,10,0.3,1.49,0.2,0.437,0.437,0.514,0,0,-1,1.7
ENSMUSG00000039032,TSGA13,testis specific gene A13,cellular_component|,biological_process|,molecular_function|,9,-0.4,0.75,10,1.5,2.3,0.1,0.435,0.435,0.515,0,0,-0.7,3
ENSMUSG00000046791,2410016O06RIK,RIKEN cDNA 2410016O06 gene,nucleus|nucleolus|nucleolar preribosome|,"chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H3-K4 demethylation|ribosome biogenesis|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|oxidation-reduction process|histone H3-K36 demethylation|","sulfonate dioxygenase activity|RNA binding|iron ion binding|protein binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|histone demethylase activity (H3-K4 specific)|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|histone demethylase activity (H3-K36 specific)|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",7,0,0,7,1,1.17,0.2,0.422,0.422,0.521,0,0,-1,2
ENSMUSG00000030317,TIMP4,tissue inhibitor of metalloproteinase 4,extracellular region|extracellular space|sarcomere|,negative regulation of peptidase activity|,enzyme inhibitor activity|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|metal ion binding|,10,0.3,0.602,10,-0.4,1.4,0.2,0.421,0.421,0.521,0,0,-1.3,1.6
ENSMUSG00000074881,MAGEB3,"melanoma antigen, family B, 3",cellular_component|,biological_process|,molecular_function|,10,0.3,1.71,10,-0.1,0.2,0.2,0.414,0.414,0.524,0,0,-1,1.7
ENSMUSG00000005656,SNX6,sorting nexin 6,nucleus|cytoplasm|endosome|membrane|cytoplasmic vesicle|early endosome membrane|,"transport|intracellular protein transport|intracellular protein transport|protein transport|negative regulation of transforming growth factor beta receptor signaling pathway|retrograde transport, endosome to Golgi|negative regulation of transcription, DNA-templated|",lipid binding|type I transforming growth factor beta receptor binding|phosphatidylinositol binding|protein homodimerization activity|,10,-0.3,0.743,10,0,0,-0.2,0.413,-0.413,0.525,0,0,-1.7,1.1
ENSMUSG00000070056,MFHAS1,malignant fibrous histiocytoma amplified sequence 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.61,10,0.1,0.13,-0.2,0.408,-0.408,0.527,0,0,-1.4,1.5
ENSMUSG00000027165,B230118H07RIK,RIKEN cDNA B230118H07 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.245,10,0.1,0.193,0.1,0.4,0.4,0.53,0,0,-0.6,2
ENSMUSG00000027649,CTNNBL1,"catenin, beta like 1",Prp19 complex|nucleus|spliceosomal complex|membrane|,apoptotic process|somatic diversification of immunoglobulins|positive regulation of apoptotic process|,protein binding|enzyme binding|,10,0.1,0.206,10,0.1,0.231,0.1,0.399,0.399,0.531,0,0,-1.3,1.6
ENSMUSG00000025237,PARP6,"poly (ADP-ribose) polymerase family, member 6",cellular_component|,biological_process|,"molecular_function|NAD+ ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.1,0.168,10,-0.2,0.5,-0.1,0.398,-0.398,0.531,0,0,-1.5,1.3
ENSMUSG00000066643,WDR35,WD repeat domain 35,intracellular|cell|cytoplasm|centrosome|cytoskeleton|cilium|axoneme|intraciliary transport particle A|intraciliary transport particle A|ciliary basal body|cell projection|,cell projection organization|intraciliary retrograde transport|cilium assembly|cilium assembly|,molecular_function|,10,0.3,0.706,10,0,0,0.2,0.395,0.395,0.532,0,0,-0.9,1.8
ENSMUSG00000063458,1700112E06RIK,RIKEN cDNA 1700112E06 gene,cellular_component|,cell differentiation|melanocyte differentiation|,molecular_function|,10,0.5,1.39,10,0,0,0.4,0.394,0.394,0.533,0,0,-0.7,1.9
ENSMUSG00000054640,SLC8A1,"solute carrier family 8 (sodium/calcium exchanger), member 1",intracellular|cell|mitochondrion|microtubule|plasma membrane|plasma membrane|integral component of plasma membrane|intercalated disc|membrane|integral component of membrane|basolateral plasma membrane|Z disc|T-tubule|T-tubule|sarcolemma|sarcolemma|cell projection|dendritic spine|dendritic shaft|,response to hypoxia|embryonic placenta development|regulation of the force of heart contraction|regulation of heart rate|regulation of sodium ion transport|heart morphogenesis|transport|ion transport|sodium ion transport|sodium ion transport|calcium ion transport|calcium ion transport|cellular calcium ion homeostasis|cell communication|positive regulation of cytosolic calcium ion concentration|post-embryonic development|positive regulation of fibroblast migration|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|vascular smooth muscle contraction|response to ATP|cellular response to reactive oxygen species|embryonic heart tube development|sodium ion transmembrane transport|relaxation of smooth muscle|muscle fiber development|negative regulation of cytosolic calcium ion concentration|regulation of calcium ion transport|cardiac muscle cell development|calcium ion homeostasis|transmembrane transport|cardiac muscle contraction|calcium ion transport into cytosol|calcium ion transport into cytosol|calcium ion import|calcium ion import|calcium ion transmembrane transport|calcium ion transmembrane transport|cellular response to caffeine|cellular response to cAMP|sodium ion export|sodium ion export|cell communication by electrical coupling involved in cardiac conduction|sodium ion import|sodium ion import|calcium ion export|calcium ion export|,calcium:sodium antiporter activity|calcium:sodium antiporter activity|calcium:sodium antiporter activity|protein binding|calmodulin binding|cytoskeletal protein binding|antiporter activity|ankyrin binding|ankyrin binding|ion channel binding|metal ion binding|,10,0.1,0.164,10,-0.8,0.49,0.1,0.393,0.393,0.533,0,0,-1.9,1.1
ENSMUSG00000073424,CYP4F15,"cytochrome P450, family 4, subfamily f, polypeptide 15",None,oxidation-reduction process|,monooxygenase activity|oxidoreductase activity|heme binding|metal ion binding|,9,0.2,0.55,9,0,0,0.1,0.391,0.391,0.534,0,0,-1.3,1.6
ENSMUSG00000068264,AP5S1,"adaptor-related protein 5 complex, sigma 1 subunit",nucleus|cytoplasm|lysosome|endosome|late endosome|membrane|AP-type membrane coat adaptor complex|,double-strand break repair via homologous recombination|DNA repair|transport|cellular response to DNA damage stimulus|protein transport|endosomal transport|,molecular_function|,9,-0.1,0.169,9,-0.1,0.253,-0.1,0.385,-0.385,0.537,0,0,-1.6,1.3
ENSMUSG00000039164,NAIF1,nuclear apoptosis inducing factor 1,nucleus|nucleus|mitochondrion|mitochondrion|plasma membrane|,apoptotic process|negative regulation of cell growth|regulation of mitochondrial membrane permeability involved in apoptotic process|regulation of mitochondrial membrane permeability involved in apoptotic process|,molecular_function|,10,0.1,0.35,10,0.1,0.0707,0.1,0.385,0.385,0.537,0,0,-1,1.8
ENSMUSG00000078667,1700094D03RIK,RIKEN cDNA 1700094D03 gene,cellular_component|,biological_process|,molecular_function|,8,0.2,0.532,8,0.1,0.0596,0.2,0.381,0.381,0.539,0,0,-1.3,1.7
ENSMUSG00000037801,IQCH,IQ motif containing H,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.819,-0.1,0.373,-0.373,0.543,0,0,-1.6,1.2
ENSMUSG00000047227,GM527,predicted gene 527,cellular_component|,biological_process|,molecular_function|,10,0.1,0.281,10,0.1,0.127,0.1,0.373,0.373,0.543,0,0,-1,1.8
ENSMUSG00000030041,M1AP,meiosis 1 associated protein,cytoplasm|integral component of membrane|,RNA processing|spermatogenesis|cell differentiation|chromatin assembly|male meiosis chromosome separation|,molecular_function|,10,0.6,1.29,10,0,0,0.3,0.372,0.372,0.543,0,0,-0.5,2
ENSMUSG00000051978,ERICH1,glutamate rich 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,0.825,0.1,0.372,0.372,0.543,0,0,-0.8,1.9
ENSMUSG00000043391,2510009E07RIK,RIKEN cDNA 2510009E07 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.743,10,0,0,0.1,0.37,0.37,0.544,0,0,-1,1.8
ENSMUSG00000032611,1700102P08RIK,RIKEN cDNA 1700102P08 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.349,10,-0.1,0.102,-0.1,0.366,-0.366,0.546,0,0,-1.8,1
ENSMUSG00000076437,2700094K13RIK,RIKEN cDNA 2700094K13 gene,None,cell redox homeostasis|,selenium binding|poly(A) RNA binding|,10,0.4,1.5,8,-0.1,0.0888,0.1,0.365,0.365,0.546,0,0,-1.4,1.5
ENSMUSG00000030098,GRIP2,glutamate receptor interacting protein 2,cytoplasm|plasma membrane|postsynaptic density|membrane|dendrite|dendritic shaft|postsynaptic membrane|,protein transport|,protein C-terminus binding|glutamate receptor binding|,10,-0.1,0.274,10,-0.1,0.124,-0.1,0.364,-0.364,0.547,0,0,-1.7,1.2
ENSMUSG00000033478,FAM160B1,"family with sequence similarity 160, member B1",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.887,10,0.4,0.969,-0.1,0.363,-0.363,0.547,0,0,-1.4,1.4
ENSMUSG00000020691,METTL2,methyltransferase like 2,cellular_component|,methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.6,2.61,10,-0.2,0.527,0.5,0.362,0.362,0.548,0,0,-0.7,1.9
ENSMUSG00000046204,PNMA2,paraneoplastic antigen MA2,cellular_component|nucleus|,biological_process|,molecular_function|,10,0.1,0.375,10,0.1,0.0183,0.1,0.36,0.36,0.548,0,0,-0.9,1.9
ENSMUSG00000041477,DCP1B,DCP1 decapping enzyme homolog B (S. cerevisiae),nucleus|cytoplasm|membrane|intracellular membrane-bounded organelle|,"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|biological_process|",molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,-0.1,0.322,10,0.2,0.535,0.1,0.359,0.359,0.549,0,0,-1,1.7
ENSMUSG00000053333,DIS3L2,DIS3 mitotic control homolog (S. cerevisiae)-like 2,cytoplasmic mRNA processing body|cytoplasm|cytoplasm|,"nuclear-transcribed mRNA catabolic process, exonucleolytic|cell cycle|mitotic nuclear division|negative regulation of cell proliferation|miRNA catabolic process|stem cell maintenance|nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'|cell division|mitotic sister chromatid separation|RNA phosphodiester bond hydrolysis|RNA phosphodiester bond hydrolysis, exonucleolytic|RNA phosphodiester bond hydrolysis, exonucleolytic|",3'-5'-exoribonuclease activity|3'-5'-exoribonuclease activity|RNA binding|nuclease activity|exonuclease activity|5'-3' exoribonuclease activity|ribonuclease activity|hydrolase activity|,10,0.2,0.674,10,0,0,0.1,0.355,0.355,0.551,0,0,-1.3,1.6
ENSMUSG00000061742,SLC22A12,"solute carrier family 22 (organic anion/cation transporter), member 12",plasma membrane|membrane|integral component of membrane|integral component of membrane|apical plasma membrane|brush border membrane|extracellular vesicular exosome|,transport|ion transport|urate transport|urate transport|organic acid transport|organic acid transport|response to drug|urate metabolic process|transmembrane transport|,protein binding|urate transmembrane transporter activity|urate transmembrane transporter activity|transmembrane transporter activity|PDZ domain binding|,10,-0.3,1.33,10,0,0,-0.1,0.353,-0.353,0.552,0,0,-1.7,1.1
ENSMUSG00000038517,TBKBP1,TBK1 binding protein 1,cellular_component|,immune system process|biological_process|innate immune response|,protein binding|,10,-0.2,0.612,10,0.2,0.694,0.1,0.348,0.348,0.554,0,0,-1.2,1.6
ENSMUSG00000056427,SLIT3,slit homolog 3 (Drosophila),extracellular region|extracellular space|extracellular space|mitochondrion|membrane|,multicellular organismal development|nervous system development|axon guidance|axon guidance|negative regulation of cell proliferation|organ morphogenesis|organ morphogenesis|negative regulation of gene expression|cell differentiation|negative regulation of cell growth|Roundabout signaling pathway|axon extension involved in axon guidance|negative chemotaxis|negative regulation of chemokine-mediated signaling pathway|,receptor binding|calcium ion binding|Roundabout binding|,10,0.2,0.917,10,-0.2,0.231,0.1,0.346,0.346,0.555,0,0,-1,1.8
ENSMUSG00000028878,FAM76A,"family with sequence similarity 76, member A",cellular_component|,biological_process|,molecular_function|,10,0.3,0.869,10,0,0,0.1,0.345,0.345,0.556,0,0,-1,1.8
ENSMUSG00000027074,SLC43A3,"solute carrier family 43, member 3",membrane|integral component of membrane|,transmembrane transport|,None,10,-0.1,0.109,10,0.2,0.328,0.1,0.344,0.344,0.556,0,0,-1.3,1.5
ENSMUSG00000025257,RIBC1,RIB43A domain with coiled-coils 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.331,10,0.1,0.0446,0.1,0.344,0.344,0.556,0,0,-1,1.8
ENSMUSG00000014496,ANKRD28,ankyrin repeat domain 28,cellular_component|nucleus|,biological_process|,None,10,-0.3,0.396,10,-0.1,0.181,-0.2,0.344,-0.344,0.556,0,0,-1.7,1.1
ENSMUSG00000038327,SERPINB9F,"serine (or cysteine) peptidase inhibitor, clade B, member 9f",cytoplasm|,hematopoietic progenitor cell differentiation|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|,10,0.2,0.455,10,-0.1,0.0732,0.2,0.34,0.34,0.558,0,0,-1,1.7
ENSMUSG00000040434,GYLTL1B,glycosyltransferase-like 1B,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|",10,0.1,0.449,10,0,0,0.1,0.339,0.339,0.559,0,0,-1.1,1.7
ENSMUSG00000036513,COMMD2,COMM domain containing 2,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.34,10,-0.5,0.463,-0.5,0.335,-0.335,0.561,0,0,-1.8,0.9
ENSMUSG00000070737,GM12942,predicted gene 12942,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,0.75,10,0,0,-0.2,0.332,-0.332,0.562,0,0,-1.8,1.1
ENSMUSG00000000204,SLFN4,schlafen 4,cellular_component|,biological_process|,molecular_function|,10,0.2,0.229,10,0.1,0.179,0.2,0.328,0.328,0.564,0,0,-0.9,1.8
ENSMUSG00000037103,DCAF15,DDB1 and CUL4 associated factor 15,cellular_component|,biological_process|,molecular_function|,10,0.1,0.408,10,-0.1,0.039,0.1,0.327,0.327,0.565,0,0,-1.5,1.4
ENSMUSG00000028621,CYB5RL,cytochrome b5 reductase-like,cellular_component|,oxidation-reduction process|,"cytochrome-b5 reductase activity, acting on NAD(P)H|oxidoreductase activity|",10,-0.1,0.455,10,0,0,-0.1,0.323,-0.323,0.567,0,0,-1.2,1.8
ENSMUSG00000011263,EXOC3L2,exocyst complex component 3-like 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.561,0.1,0.323,0.323,0.567,0,0,-0.8,2
ENSMUSG00000028018,GSTCD,"glutathione S-transferase, C-terminal domain containing",extracellular vesicular exosome|,biological_process|,protein binding|,10,0.4,0.777,10,0,0,0.2,0.315,0.315,0.571,0,0,-1,1.8
ENSMUSG00000035513,NTNG2,netrin G2,plasma membrane|membrane|axon|anchored component of membrane|anchored component of plasma membrane|,multicellular organismal development|nervous system development|axonogenesis|cell differentiation|,protein binding|,10,-0.2,0.414,10,0.2,0.512,-0.1,0.313,-0.313,0.572,0,0,-1.5,1.4
ENSMUSG00000007833,ALDH16A1,"aldehyde dehydrogenase 16 family, member A1",membrane|extracellular vesicular exosome|,metabolic process|oxidation-reduction process|,"oxidoreductase activity|oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor|",10,-1,2.64,10,0.5,1.76,0.1,0.31,0.31,0.573,0,0,-2,0.9
ENSMUSG00000042675,YPEL3,yippee-like 3 (Drosophila),cellular_component|nucleus|,apoptotic process|biological_process|,molecular_function|,10,-0.1,0.324,10,-0.1,0.0127,-0.1,0.309,-0.309,0.573,0,0,-1.8,1
ENSMUSG00000030491,TDRD12,tudor domain containing 12,cellular_component|,meiotic nuclear division|male meiosis|multicellular organismal development|spermatogenesis|fertilization|cell differentiation|gene silencing by RNA|piRNA metabolic process|DNA methylation involved in gamete generation|,nucleotide binding|molecular_function|nucleic acid binding|helicase activity|ATP binding|hydrolase activity|,10,0,0,10,-0.4,2.6,-0.3,0.307,-0.307,0.575,0,0,-1.3,1.8
ENSMUSG00000017679,TTPAL,tocopherol (alpha) transfer protein-like,intracellular|membrane|,transport|biological_process|,molecular_function|transporter activity|,10,-0.1,0.145,10,0.1,0.405,0.1,0.307,0.307,0.575,0,0,-1.4,1.4
ENSMUSG00000038793,LEFTY1,left right determination factor 1,extracellular region|extracellular space|,negative regulation of transcription from RNA polymerase II promoter|heart morphogenesis|multicellular organismal development|determination of left/right symmetry|negative regulation of cell proliferation|anterior/posterior axis specification|cell growth|response to retinoic acid|growth|cell migration involved in gastrulation|negative regulation of nodal signaling pathway|negative regulation of nodal receptor complex assembly|,cytokine activity|transforming growth factor beta receptor binding|growth factor activity|nodal binding|,10,0.1,0.247,10,-0.2,0.361,-0.2,0.307,-0.307,0.575,0,0,-1.7,1.1
ENSMUSG00000079012,SERPINA3M,"serine (or cysteine) peptidase inhibitor, clade A, member 3M",extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.1,0.291,10,-0.1,0.0441,-0.1,0.307,-0.307,0.575,0,0,-1.8,0.9
ENSMUSG00000026578,CCDC181,coiled-coil domain containing 181,nucleus|,biological_process|,molecular_function|,10,0,0,10,0.3,1.28,0.1,0.306,0.306,0.575,0,0,-1.2,1.7
ENSMUSG00000030532,HDDC3,HD domain containing 3,cellular_component|,biological_process|,"molecular_function|guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity|hydrolase activity|metal ion binding|",10,-0.4,1.51,10,0,0,-0.4,0.305,-0.305,0.575,0,0,-1.7,1
ENSMUSG00000044795,CYB5D1,cytochrome b5 domain containing 1,cellular_component|,biological_process|,molecular_function|heme binding|metal ion binding|,10,0.1,0.421,10,0,0,0.1,0.302,0.302,0.577,0,0,-1,1.8
ENSMUSG00000046287,PNMA3,paraneoplastic antigen MA3,cellular_component|nucleus|,biological_process|,molecular_function|nucleic acid binding|zinc ion binding|metal ion binding|,10,-0.1,0.142,10,0.3,0.808,0.2,0.299,0.299,0.579,0,0,-1.1,1.6
ENSMUSG00000073096,LRRC61,leucine rich repeat containing 61,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0795,10,0.1,0.247,0.1,0.298,0.298,0.579,0,0,-1.2,1.7
ENSMUSG00000029469,IFT81,intraflagellar transport 81,intracellular|cell|centrosome|cilium|cilium|intraciliary transport particle B|cell projection|sperm midpiece|sperm principal piece|,multicellular organismal development|spermatogenesis|cell projection organization|cell differentiation|intraciliary transport involved in cilium morphogenesis|intraciliary transport|intraciliary transport|cilium assembly|cilium assembly|,protein binding|tubulin binding|tubulin binding|,10,0.1,0.122,10,0.2,0.215,0.1,0.297,0.297,0.58,0,0,-1.2,1.6
ENSMUSG00000039774,GALNT12,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-0.7,0.408,10,0.1,0.169,-0.3,0.297,-0.297,0.58,0,0,-1.8,0.9
ENSMUSG00000020107,ANAPC16,anaphase promoting complex subunit 16,nucleus|anaphase-promoting complex|cytoplasm|,cell cycle|mitotic nuclear division|protein ubiquitination|cell division|,molecular_function|,10,0.2,0.261,10,0.1,0.0996,0.1,0.296,0.296,0.58,0,0,-1.2,1.7
ENSMUSG00000072640,LYRM9,LYR motif containing 9,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.871,-0.1,0.296,-0.296,0.58,0,0,-1.5,1.4
ENSMUSG00000003153,SLC2A3,"solute carrier family 2 (facilitated glucose transporter), member 3",acrosomal membrane|cytoplasm|cytoplasm|plasma membrane|plasma membrane|caveola|membrane|integral component of membrane|synaptic vesicle membrane|extracellular vesicular exosome|,transport|carbohydrate transport|glucose transport|glucose transport|glucose transport|hexose transmembrane transport|transmembrane transport|dehydroascorbic acid transport|dehydroascorbic acid transport|,transporter activity|glucose transmembrane transporter activity|glucose binding|monosaccharide transmembrane transporter activity|galactoside binding|kinase binding|transmembrane transporter activity|substrate-specific transmembrane transporter activity|xylose binding|dehydroascorbic acid transporter activity|dehydroascorbic acid transporter activity|D-glucose transmembrane transporter activity|D-glucose transmembrane transporter activity|,10,-0.2,0.498,10,0,0,-0.1,0.296,-0.296,0.58,0,0,-1.6,1.2
ENSMUSG00000027925,SPRR2J-PS,"small proline-rich protein 2J, pseudogene",None,None,None,10,0,0,10,-0.4,1.49,-0.1,0.296,-0.296,0.58,0,0,-1.9,0.8
ENSMUSG00000025795,RASSF3,Ras association (RalGDS/AF-6) domain family member 3,cytoplasm|cytoskeleton|microtubule|plasma membrane|,signal transduction|,identical protein binding|,10,-0.1,0.45,10,0,0,-0.1,0.295,-0.295,0.581,0,0,-1.6,1.3
ENSMUSG00000023330,DTWD1,DTW domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.11,10,0.1,0.207,0.1,0.289,0.289,0.584,0,0,-1,1.9
ENSMUSG00000039713,PLEKHG5,"pleckstrin homology domain containing, family G (with RhoGef domain) member 5",cytoplasm|plasma membrane|cell-cell junction|lamellipodium|cell junction|endocytic vesicle|cell projection|,signal transduction|positive regulation of Rho GTPase activity|regulation of Rho protein signal transduction|endothelial cell chemotaxis|positive regulation of I-kappaB kinase/NF-kappaB signaling|endothelial cell migration|,signal transducer activity|Rho guanyl-nucleotide exchange factor activity|protein binding|,10,-0.2,0.221,10,0.4,1.53,0.1,0.279,0.279,0.589,0,0,-0.9,1.9
ENSMUSG00000042200,CDRT4,CMT1A duplicated region transcript 4,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.518,10,0.6,2.43,-0.1,0.276,-0.276,0.591,0,0,-0.8,1.8
ENSMUSG00000041153,OSGIN2,oxidative stress induced growth inhibitor family member 2,cellular_component|,biological_process|,molecular_function|,10,0.1,0.492,9,0,0,0.1,0.271,0.271,0.593,0,0,-1.1,1.8
ENSMUSG00000034303,CCDC15,coiled-coil domain containing 15,centrosome|,biological_process|,molecular_function|,10,0,0,10,0.2,0.645,0.2,0.271,0.271,0.593,0,0,-1.1,1.7
ENSMUSG00000062651,H2AFB1,"H2A histone family, member B1",nucleosome|nucleus|chromosome|,mRNA processing|,DNA binding|protein heterodimerization activity|,10,-0.1,0.209,10,0.2,0.977,0.2,0.268,0.268,0.595,0,0,-1.2,1.6
ENSMUSG00000044060,A830010M20RIK,RIKEN cDNA A830010M20 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.464,0.1,0.264,0.264,0.597,0,0,-1.2,1.7
ENSMUSG00000028108,ECM1,extracellular matrix protein 1,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|extracellular vesicular exosome|,ossification|angiogenesis|positive regulation of endothelial cell proliferation|negative regulation of cytokine-mediated signaling pathway|regulation of type 2 immune response|regulation of transcription from RNA polymerase II promoter|inflammatory response|signal transduction|negative regulation of peptidase activity|regulation of bone mineralization|negative regulation of bone mineralization|biomineral tissue development|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of angiogenesis|regulation of T cell migration|,protease binding|signal transducer activity|interleukin-2 receptor binding|protein C-terminus binding|enzyme binding|laminin binding|,10,-0.1,0.0694,10,-0.1,0.219,-0.1,0.263,-0.263,0.598,0,0,-1.7,1.3
ENSMUSG00000020955,AP4S1,"adaptor-related protein complex AP-4, sigma 1",Golgi apparatus|trans-Golgi network|coated pit|membrane|,transport|intracellular protein transport|protein transport|vesicle-mediated transport|,protein transporter activity|,10,-0.2,0.663,10,0.5,1.37,0.1,0.262,0.262,0.599,0,0,-1.3,1.6
ENSMUSG00000039246,LYPLAL1,lysophospholipase-like 1,cytoplasm|cytosol|extracellular vesicular exosome|,protein depalmitoylation|negative regulation of Golgi to plasma membrane protein transport|,"molecular_function|CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0.1,0.309,10,-0.3,0.84,0.1,0.257,0.257,0.601,0,0,-1.5,1.3
ENSMUSG00000050373,SNX21,sorting nexin family member 21,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.788,10,0,0,-0.1,0.255,-0.255,0.603,0,0,-1.7,1.1
ENSMUSG00000032246,CALML4,calmodulin-like 4,None,None,calcium ion binding|,10,0.2,0.228,10,-0.1,0.0712,-0.1,0.254,-0.254,0.603,0,0,-1.4,1.5
ENSMUSG00000005360,SLC1A3,"solute carrier family 1 (glial high affinity glutamate transporter), member 3",mitochondrial inner membrane|plasma membrane|plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|cell projection|neuron projection|neuronal cell body|dendritic spine|fibril|synapse|,glutamate metabolic process|glutamate biosynthetic process|transport|dicarboxylic acid transport|sensory perception of sound|response to light stimulus|gamma-aminobutyric acid biosynthetic process|response to wounding|response to inorganic substance|L-glutamate transport|L-glutamate transport|cranial nerve development|auditory behavior|sodium ion transmembrane transport|response to drug|response to amino acid|malate-aspartate shuttle|response to antibiotic|cell morphogenesis involved in neuron differentiation|positive regulation of synaptic transmission|neuromuscular process controlling balance|L-glutamate import|L-glutamate import|D-aspartate import|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|high-affinity glutamate transmembrane transporter activity|high-affinity glutamate transmembrane transporter activity|high-affinity glutamate transmembrane transporter activity|protein binding|symporter activity|glutamate binding|amino acid binding|sodium:dicarboxylate symporter activity|,10,0,0,10,0.3,0.7,0.3,0.253,0.253,0.604,0,0,-0.9,1.8
ENSMUSG00000034647,ANKRD12,ankyrin repeat domain 12,nucleus|cytoplasm|,biological_process|,molecular_function|,9,0.1,0.316,9,-0.2,0.504,0.1,0.253,0.253,0.604,0,0,-1.3,1.8
ENSMUSG00000071547,NT5DC2,5'-nucleotidase domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0.2,0.196,10,0.1,0.0831,0.1,0.253,0.253,0.604,0,0,-1.5,1.4
ENSMUSG00000024565,SALL3,sal-like 3 (Drosophila),nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|olfactory bulb interneuron development|forelimb morphogenesis|hindlimb morphogenesis|negative regulation of smoothened signaling pathway|",nucleic acid binding|DNA binding|metal ion binding|,10,0.2,0.897,10,0,0,0.1,0.252,0.252,0.604,0,0,-1.1,1.7
ENSMUSG00000028642,4930538K18RIK,RIKEN cDNA 4930538K18 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.568,10,-0.1,0.188,0.3,0.249,0.249,0.606,0,0,-0.9,1.7
ENSMUSG00000071691,GM960,predicted gene 960,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.509,0.1,0.248,0.248,0.606,0,0,-1,1.8
ENSMUSG00000095105,EDARADD,EDAR (ectodysplasin-A receptor)-associated death domain,cytoplasm|,hair follicle development|signal transduction|I-kappaB kinase/NF-kappaB signaling|multicellular organismal development|cell differentiation|odontogenesis of dentin-containing tooth|trachea gland development|,death receptor binding|protein binding|,9,0.1,0.161,9,0.2,0.156,0.1,0.247,0.247,0.607,0,0,-1.1,1.8
ENSMUSG00000048827,PKD1L3,polycystic kidney disease 1 like 3,plasma membrane|cell surface|membrane|integral component of membrane|extracellular vesicular exosome|,detection of chemical stimulus involved in sensory perception of sour taste|transport|ion transport|cation transport|calcium ion transport|neuropeptide signaling pathway|sensory perception of sour taste|detection of mechanical stimulus|calcium ion transmembrane transport|cellular response to acidity|,cation channel activity|calcium channel activity|calcium ion binding|protein binding|cation transmembrane transporter activity|carbohydrate binding|sour taste receptor activity|,10,0.1,0.519,10,0,0,0.1,0.247,0.247,0.607,0,0,-1.2,1.7
ENSMUSG00000039137,WHRN,whirlin,photoreceptor inner segment|stereocilia ankle link complex|cytoplasm|actin filament|cilium|membrane|axon|dendrite|photoreceptor connecting cilium|stereocilium|stereocilium|stereocilium bundle|cell projection|neuronal cell body|neuronal cell body|dendritic shaft|synapse|,retina homeostasis|sensory perception of sound|sensory perception of sound|sensory perception of light stimulus|inner ear receptor stereocilium organization|,protein binding|protein domain specific binding|,10,0,0,10,-0.2,0.694,-0.1,0.242,-0.242,0.61,0,0,-1.7,1.2
ENSMUSG00000028807,ZBTB8A,zinc finger and BTB domain containing 8a,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,0.2,0.873,10,0,0,0.1,0.24,0.24,0.611,0,0,-1.5,1.4
ENSMUSG00000022211,LRRC16B,leucine rich repeat containing 16B,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.3,0.491,10,0.1,0.0378,0.3,0.24,0.24,0.611,0,0,-0.9,1.8
ENSMUSG00000027901,DENND2D,DENN/MADD domain containing 2D,cellular_component|cytoplasm|,positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.1,0.0313,10,0.4,1.34,0.1,0.237,0.237,0.613,0,0,-1,1.7
ENSMUSG00000045539,SPRR3,small proline-rich protein 3,cytoplasm|extracellular vesicular exosome|,peptide cross-linking|keratinization|,protein binding|,10,-0.2,0.703,10,0,0,-0.1,0.233,-0.233,0.615,0,0,-1.9,0.9
ENSMUSG00000020332,4930404A10RIK,RIKEN cDNA 4930404A10 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0225,10,0.6,1.45,0.2,0.227,0.227,0.618,0,0,-0.6,1.9
ENSMUSG00000051427,CCDC157,coiled-coil domain containing 157,cellular_component|,biological_process|,molecular_function|,10,0.2,0.387,10,0,0,0.1,0.227,0.227,0.618,0,0,-1.1,1.8
ENSMUSG00000024176,SOX8,SRY (sex determining region Y)-box 8,nucleus|nucleus|cytoplasm|cytoplasm|nuclear transcription factor complex|,"osteoblast differentiation|in utero embryonic development|neural crest cell migration|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|signal transduction|spermatogenesis|spermatogenesis|peripheral nervous system development|male gonad development|positive regulation of gene expression|regulation of hormone levels|positive regulation of gliogenesis|positive regulation of osteoblast proliferation|skeletal muscle cell differentiation|negative regulation of apoptotic process|cell fate commitment|fat cell differentiation|negative regulation of myoblast differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of photoreceptor cell differentiation|cell maturation|cell maturation|enteric nervous system development|oligodendrocyte differentiation|Sertoli cell development|astrocyte fate commitment|retina development in camera-type eye|retinal rod cell differentiation|adipose tissue development|morphogenesis of a branching epithelium|renal vesicle induction|ureter morphogenesis|metanephric nephron tubule formation|positive regulation of kidney development|positive regulation of branching involved in ureteric bud morphogenesis|",RNA polymerase II core promoter sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|sequence-specific DNA binding|protein heterodimerization activity|,10,0.3,0.522,10,0.1,0.055,0.2,0.223,0.223,0.62,0,0,-1.2,1.7
ENSMUSG00000036745,TTLL7,"tubulin tyrosine ligase-like family, member 7",cytoplasm|cytoskeleton|cilium|cell projection|,cellular protein modification process|multicellular organismal development|nervous system development|protein polyglutamylation|cell differentiation|,ligase activity|,10,-0.1,0.188,10,-0.1,0.0566,-0.1,0.223,-0.223,0.62,0,0,-1.5,1.4
ENSMUSG00000044287,NRN1L,neuritin 1-like,plasma membrane|membrane|anchored component of membrane|,nervous system development|,None,10,-0.1,0.469,10,0.2,0.0678,-0.1,0.22,-0.22,0.622,0,0,-1.3,1.5
ENSMUSG00000036188,ANKMY2,ankyrin repeat and MYND domain containing 2,cellular_component|cilium|cell projection|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0.2,0.37,0.1,0.215,0.215,0.625,0,0,-1,1.8
ENSMUSG00000030889,VWA3A,von Willebrand factor A domain containing 3A,cellular_component|,biological_process|,molecular_function|,10,0.1,0.219,10,-0.3,0.751,-0.3,0.207,-0.207,0.63,0,0,-1.6,1.1
ENSMUSG00000042997,NHLRC3,NHL repeat containing 3,extracellular vesicular exosome|,biological_process|,molecular_function|,9,-0.2,0.691,9,0,0,-0.1,0.204,-0.204,0.631,0,0,-1.6,1.4
ENSMUSG00000050821,FAM131A,"family with sequence similarity 131, member A",cellular_component|extracellular region|,biological_process|,molecular_function|,9,-1,0.453,9,0,0,-0.9,0.201,-0.201,0.633,0,0,-2,0.8
ENSMUSG00000029775,KLHDC10,kelch domain containing 10,cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0.2,0.522,0.1,0.2,0.2,0.634,0,0,-1.4,1.5
ENSMUSG00000058207,SERPINA3K,"serine (or cysteine) peptidase inhibitor, clade A, member 3K",extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,serine-type endopeptidase inhibitor activity|protein binding|peptidase inhibitor activity|,9,0,0,10,0.2,0.829,0.2,0.199,0.199,0.634,0,0,-0.9,1.9
ENSMUSG00000048982,GPHB5,glycoprotein hormone beta 5,cellular_component|extracellular region|,regulation of thyroid hormone mediated signaling pathway|,molecular_function|hormone activity|,10,0.1,0.32,10,-0.2,0.527,0.1,0.195,0.195,0.636,0,0,-1.4,1.4
ENSMUSG00000040658,DNPH1,2'-deoxynucleoside 5'-phosphate N-hydrolase 1,nucleus|cytoplasm|extracellular vesicular exosome|,metabolic process|nucleotide metabolic process|deoxyribonucleoside monophosphate catabolic process|positive regulation of cell growth|,"purine-specific mismatch base pair DNA N-glycosylase activity|uracil DNA N-glycosylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|single-strand selective uracil DNA N-glycosylase activity|DNA N-glycosylase activity|protein homodimerization activity|DNA-3-methylbase glycosylase activity|nucleoside deoxyribosyltransferase activity|nicotinamide riboside hydrolase activity|nicotinic acid riboside hydrolase activity|deoxyribonucleoside 5'-monophosphate N-glycosidase activity|",10,0,0,10,-0.1,0.471,-0.1,0.194,-0.194,0.637,0,0,-1.6,1.4
ENSMUSG00000039879,HECA,headcase homolog (Drosophila),membrane|,biological_process|,molecular_function|,10,0.1,0.515,10,-0.1,0.179,0.1,0.192,0.192,0.638,0,0,-1.6,1.3
ENSMUSG00000048039,ISG20L2,interferon stimulated exonuclease gene 20-like 2,nucleus|,biological_process|ribosome biogenesis|,nucleic acid binding|nuclease activity|exonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|poly(A) RNA binding|retroviral 3' processing activity|,10,0.1,0.0318,10,0.1,0.174,0.1,0.188,0.188,0.64,0,0,-1.5,1.5
ENSMUSG00000034387,SSU2,ssu-2 homolog (C. elegans),cytoplasm|,biological_process|,molecular_function|heat shock protein binding|unfolded protein binding|,10,-0.2,1.72,10,0.1,0.17,-0.1,0.188,-0.188,0.64,0,0,-1.5,1.4
ENSMUSG00000050545,FAM228B,"family with sequence similarity 228, member B",cellular_component|,biological_process|,molecular_function|,10,0.2,0.328,10,0,0,0.1,0.187,0.187,0.641,0,0,-1.1,1.7
ENSMUSG00000046470,SOX18,SRY (sex determining region Y)-box 18,nuclear chromatin|nucleus|nucleus|nucleus|nuclear transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|angiogenesis|blood vessel development|vasculogenesis|in utero embryonic development|hair follicle development|vasculature development|lymph vessel development|lymphangiogenesis|lymphangiogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|heart development|hair cycle process|embryonic heart tube development|mRNA transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|cell maturation|stem cell fate specification|endocardium formation|lymphatic endothelial cell differentiation|endocardial cell differentiation|establishment of endothelial barrier|regulation of stem cell proliferation|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0,0,10,0.3,1.47,0.2,0.187,0.187,0.641,0,0,-0.7,2
ENSMUSG00000032870,SMAP2,small ArfGAP 2,nucleus|cytoplasm|,regulation of ARF GTPase activity|,GTPase activator activity|ARF GTPase activator activity|zinc ion binding|metal ion binding|,10,0.2,0.531,10,-0.3,1.9,-0.1,0.186,-0.186,0.641,0,0,-1.6,1.2
ENSMUSG00000049323,SMCR8,"Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)",nucleus|,biological_process|,molecular_function|,9,0.1,0.155,9,0.1,0.048,0.1,0.185,0.185,0.642,0,0,-1.3,1.7
ENSMUSG00000018593,SPARC,secreted acidic cysteine rich glycoprotein,extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|intracellular|nucleus|cytoplasm|extracellular matrix|membrane-bounded vesicle|,signal transduction|lung development|regulation of cell proliferation|bone development|cellular response to growth factor stimulus|,calcium ion binding|metal ion binding|extracellular matrix binding|,10,0,0,10,0.2,0.566,0.1,0.184,0.184,0.642,0,0,-1.2,1.7
ENSMUSG00000035443,THYN1,thymocyte nuclear protein 1,nucleus|nucleus|,biological_process|,molecular_function|,10,0.5,0.176,10,-0.3,1.37,-0.1,0.183,-0.183,0.643,0,0,-1.2,1.6
ENSMUSG00000036167,PPHLN1,periphilin 1,nucleus|cytoplasm|Golgi apparatus|intracellular membrane-bounded organelle|,keratinization|,poly(A) RNA binding|,10,0.1,0.201,10,-0.1,0.0671,0.1,0.178,0.178,0.645,0,0,-1.1,1.8
ENSMUSG00000002147,STAT6,signal transducer and activator of transcription 6,nuclear chromatin|nucleus|nucleus|cytoplasm|cytoplasm|membrane raft|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|T-helper 1 cell lineage commitment|negative regulation of type 2 immune response|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|cytokine-mediated signaling pathway|mammary gland epithelial cell proliferation|response to cytokine|interleukin-4-mediated signaling pathway|interleukin-4-mediated signaling pathway|regulation of cell proliferation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of isotype switching to IgE isotypes|mammary gland morphogenesis|cellular response to hydrogen peroxide|cellular response to reactive nitrogen species|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|calcium ion binding|protein phosphatase binding|identical protein binding|sequence-specific DNA binding|sequence-specific DNA binding|,10,0.1,0.439,10,0,0,0.1,0.176,0.176,0.647,0,0,-1.2,1.7
ENSMUSG00000029141,SLC4A1AP,"solute carrier family 4 (anion exchanger), member 1, adaptor protein",cellular_component|,biological_process|,protein binding|,10,0,0,10,0.2,0.691,0.1,0.175,0.175,0.647,0,0,-1,1.9
ENSMUSG00000016995,MATN4,matrilin 4,extracellular region|,response to axon injury|,None,10,0.2,0.399,9,0,0,0.1,0.172,0.172,0.649,0,0,-0.7,2
ENSMUSG00000059866,TNIP2,TNFAIP3 interacting protein 2,cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|apoptotic process|inflammatory response|I-kappaB kinase/NF-kappaB signaling|CD40 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 9 signaling pathway|positive regulation of macrophage activation|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of transcription from RNA polymerase II promoter|protein stabilization|positive regulation of B cell activation|interleukin-1-mediated signaling pathway|cellular response to lipopolysaccharide|negative regulation of endothelial cell apoptotic process|",protein binding|protein kinase binding|polyubiquitin binding|,10,0.2,0.787,10,0,0,0.1,0.17,0.17,0.65,0,0,-1.4,1.4
ENSMUSG00000035711,DOK3,docking protein 3,cytoplasm|plasma membrane|membrane|,Ras protein signal transduction|,insulin receptor binding|protein binding|,10,0.1,0.316,10,-0.5,0.79,0.1,0.168,0.168,0.652,0,0,-1.3,1.7
ENSMUSG00000024188,LUC7L,Luc7 homolog (S. cerevisiae)-like,nucleus|U1 snRNP|,mRNA splice site selection|negative regulation of striated muscle tissue development|,mRNA binding|protein binding|identical protein binding|RS domain binding|,10,0,0,10,-0.3,0.811,-0.1,0.166,-0.166,0.653,0,0,-2,0.8
ENSMUSG00000033955,TNKS1BP1,tankyrase 1 binding protein 1,nucleus|chromosome|cytoplasm|cytoskeleton|CCR4-NOT complex|,biological_process|,molecular_function|,10,-0.2,0.369,10,0,0,-0.1,0.157,-0.157,0.658,0,0,-1.9,0.9
ENSMUSG00000039046,USP6NL,USP6 N-terminal like,Golgi apparatus|cytoplasmic vesicle|,"Golgi organization|regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|retrograde transport, plasma membrane to Golgi|",GTPase activator activity|Rab GTPase activator activity|,10,0.6,0.752,10,0,0,0.1,0.156,0.156,0.659,0,0,-1,1.9
ENSMUSG00000028931,KCNAB2,"potassium voltage-gated channel, shaker-related subfamily, beta member 2",cytoplasm|integral component of membrane|juxtaparanode region of axon|,hematopoietic progenitor cell differentiation|transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein heterooligomerization|,voltage-gated ion channel activity|voltage-gated potassium channel activity|protein binding|,10,0,0,10,0.2,0.421,0.1,0.156,0.156,0.659,0,0,-1.1,1.8
ENSMUSG00000023084,LRRC71,leucine rich repeat containing 71,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.723,-0.1,0.155,-0.155,0.66,0,0,-1.6,1.3
ENSMUSG00000057068,FAM47E,"family with sequence similarity 47, member E",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.947,-0.2,0.152,-0.152,0.661,0,0,-1.7,1.1
ENSMUSG00000074818,PDZD7,PDZ domain containing 7,extracellular space|nucleus|cilium|,None,None,10,-0.3,0.795,10,0.2,0.811,-0.1,0.148,-0.148,0.664,0,0,-1.4,1.4
ENSMUSG00000058706,0610030E20RIK,RIKEN cDNA 0610030E20 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,1.38,0.1,0.148,0.148,0.664,0,0,-1.8,1.3
ENSMUSG00000061882,CCDC62,coiled-coil domain containing 62,nucleus|cytoplasm|plasma membrane|,positive regulation of transcription from RNA polymerase II promoter|cellular response to estradiol stimulus|,estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|,10,0.3,1.07,10,0,0,0.1,0.147,0.147,0.664,0,0,-1.2,1.7
ENSMUSG00000049687,FAM109B,"family with sequence similarity 109, member B",endosome|early endosome|Golgi apparatus|trans-Golgi network|clathrin-coated vesicle|cytoplasmic vesicle|recycling endosome|,"receptor recycling|endosome organization|retrograde transport, endosome to Golgi|",protein homodimerization activity|,10,-0.1,0.0838,10,0.4,1.45,0.1,0.145,0.145,0.665,0,0,-0.7,2
ENSMUSG00000048655,CCDC169,coiled-coil domain containing 169,cellular_component|,biological_process|,molecular_function|,10,0.3,0.204,10,0.2,0.0515,0.2,0.143,0.143,0.667,0,0,-0.9,1.8
ENSMUSG00000050625,CCDC121,coiled-coil domain containing 121,cellular_component|,biological_process|,molecular_function|,10,0.2,0.221,10,0.1,0.0169,0.1,0.141,0.141,0.668,0,0,-1.1,1.8
ENSMUSG00000001095,SLC13A2,"solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2",membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|transmembrane transport|,transporter activity|symporter activity|,10,0.1,0.0457,10,0.1,0.108,0.1,0.14,0.14,0.668,0,0,-1.3,1.6
ENSMUSG00000013076,AMOTL1,angiomotin-like 1,cytoplasm|tight junction|tight junction|COP9 signalosome|apical plasma membrane|lamellipodium|cell junction|cytoplasmic vesicle|,establishment of cell polarity involved in ameboidal cell migration|Wnt signaling pathway|hippo signaling|positive regulation of blood vessel endothelial cell migration|,protein binding|identical protein binding|,10,-0.2,0.78,10,0,0,-0.1,0.139,-0.139,0.669,0,0,-2,0.9
ENSMUSG00000024041,CRYAA,"crystallin, alpha A",nucleus|cytoplasm|cytoplasm|extracellular vesicular exosome|,response to hypoxia|positive regulation of protein phosphorylation|lens development in camera-type eye|lens development in camera-type eye|lens morphogenesis in camera-type eye|protein folding|apoptotic process|mitochondrion organization|actin filament organization|microtubule-based process|tubulin complex assembly|negative regulation of gene expression|positive regulation of cell growth|response to hydrogen peroxide|response to hydrogen peroxide|camera-type eye development|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|embryonic camera-type eye morphogenesis|protein homooligomerization|apoptotic process involved in morphogenesis|response to UV-A|lens fiber cell morphogenesis|,structural constituent of eye lens|protein binding|identical protein binding|metal ion binding|unfolded protein binding|,10,0.1,0.00932,10,-0.2,0.651,0.1,0.137,0.137,0.67,0,0,-1.4,1.5
ENSMUSG00000029168,DPYSL5,dihydropyrimidinase-like 5,cytoplasm|dendrite|neuronal cell body|protein complex|,pyrimidine nucleobase catabolic process|axon guidance|,"protein binding|hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|",10,-0.1,0.146,10,0.1,0.0199,0.1,0.136,0.136,0.671,0,0,-1.4,1.5
ENSMUSG00000032502,STAC,src homology three (SH3) and cysteine rich domain,cellular_component|cytoplasm|,cellular response to heat|intracellular signal transduction|,molecular_function|metal ion binding|,10,0,0,10,0.1,0.193,0.1,0.136,0.136,0.671,0,0,-1,1.9
ENSMUSG00000018427,YPEL2,yippee-like 2 (Drosophila),cellular_component|nucleus|,biological_process|,molecular_function|,10,0.1,0.163,10,0,0,0.1,0.135,0.135,0.671,0,0,-1.1,1.8
ENSMUSG00000040506,AMBRA1,autophagy/beclin 1 regulator 1,cytoplasm|axoneme|cytoplasmic vesicle|phagocytic vesicle|,autophagy|multicellular organismal development|nervous system development|negative regulation of cell proliferation|embryo development|neural tube development|cell differentiation|negative regulation of neuron apoptotic process|,protein binding|,10,-0.1,0.203,10,0,0,-0.1,0.134,-0.134,0.672,0,0,-1.7,1.2
ENSMUSG00000014813,STC1,stanniocalcin 1,extracellular region|extracellular space|cytoplasm|apical plasma membrane|,ossification|cellular calcium ion homeostasis|cellular monovalent inorganic anion homeostasis|,hormone activity|,10,0.2,1.18,10,-0.1,0.47,0.1,0.131,0.131,0.674,0,0,-1.2,1.6
ENSMUSG00000056018,1700008F21RIK,RIKEN cDNA 1700008F21 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.667,0.1,0.13,0.13,0.674,0,0,-1.3,1.5
ENSMUSG00000025372,BAIAP2,brain-specific angiogenesis inhibitor 1-associated protein 2,intracellular|cytoplasm|cytosol|cytoskeleton|actin cytoskeleton|membrane|cell projection|neuron projection|extracellular vesicular exosome|,signal transduction|Rho protein signal transduction|regulation of cell shape|response to bacterium|dendrite development|regulation of actin cytoskeleton organization|filopodium assembly|regulation of synaptic plasticity|actin filament bundle assembly|actin filament bundle assembly|actin crosslink formation|,protein binding|cytoskeletal adaptor activity|SH3 domain binding|identical protein binding|proline-rich region binding|,9,-0.1,0.282,9,0,0,-0.1,0.13,-0.13,0.674,0,0,-2,0.9
ENSMUSG00000022876,SAMSN1,"SAM domain, SH3 domain and nuclear localization signals, 1",nucleus|nucleus|cytoplasm|cytosol|cell projection|,negative regulation of adaptive immune response|negative regulation of peptidyl-tyrosine phosphorylation|negative regulation of B cell activation|,phosphotyrosine binding|poly(A) RNA binding|,10,0,0,10,-0.4,2.3,-0.3,0.127,-0.127,0.677,0,0,-1.8,1
ENSMUSG00000039345,METTL22,methyltransferase like 22,cellular_component|nucleus|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.2,1.31,10,0,0,0.1,0.125,0.125,0.678,0,0,-1.2,1.7
ENSMUSG00000055865,FAM19A3,"family with sequence similarity 19, member A3",cellular_component|extracellular region|,biological_process|,molecular_function|,10,-1.1,0.936,9,0.1,0.339,0.1,0.125,0.125,0.678,0,0,-2,1.2
ENSMUSG00000047344,LANCL3,LanC lantibiotic synthetase component C-like 3 (bacterial),cellular_component|,biological_process|,molecular_function|catalytic activity|,7,0.7,1.06,7,-0.9,1.37,-0.1,0.125,-0.125,0.678,0,0,-1.8,1.6
ENSMUSG00000040648,PPIP5K2,diphosphoinositol pentakisphosphate kinase 2,cytoplasm|,phosphorylation|,nucleotide binding|inositol hexakisphosphate 5-kinase activity|acid phosphatase activity|ATP binding|kinase activity|transferase activity|diphosphoinositol-pentakisphosphate kinase activity|inositol hexakisphosphate 1-kinase activity|inositol hexakisphosphate 3-kinase activity|,10,0,0,10,-0.7,1.42,0.1,0.124,0.124,0.678,0,0,-1.8,1.3
ENSMUSG00000037818,3110057O12RIK,RIKEN cDNA 3110057O12 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.3,0.912,10,0,0,-0.1,0.122,-0.122,0.68,0,0,-1.8,1
ENSMUSG00000043987,CEP164,centrosomal protein 164,extracellular space|nucleus|cytoplasm|centrosome|centriole|centriole|cytoskeleton|cilium|ciliary transition fiber|,DNA repair|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|cell projection organization|cilium assembly|cell division|,protein binding|,10,0.5,0.684,10,0,0,0.4,0.122,0.122,0.68,0,0,-1.1,1.8
ENSMUSG00000078794,DACT3,"dapper homolog 3, antagonist of beta-catenin (xenopus)",cytoplasm|,negative regulation of epithelial to mesenchymal transition|Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of cell growth|negative regulation of catenin import into nucleus|negative regulation of canonical Wnt signaling pathway|,protein kinase C binding|protein binding|identical protein binding|protein kinase A binding|delta-catenin binding|,10,0.1,0.243,10,-0.2,0.385,-0.1,0.121,-0.121,0.68,0,0,-1.5,1.4
ENSMUSG00000029848,STRA8,stimulated by retinoic acid gene 8,nucleus|cytoplasm|,ovarian follicle development|DNA replication|female meiosis sister chromatid cohesion|meiotic nuclear division|synapsis|reciprocal meiotic recombination|spermatogenesis|fertilization|meiotic chromosome condensation|meiotic DNA replication checkpoint|meiotic DNA double-strand break formation|regulation of organ growth|oocyte development|cellular response to retinoic acid|,protein binding|,10,-0.5,0.823,10,0,0,-0.1,0.12,-0.12,0.681,0,0,-1.9,0.9
ENSMUSG00000038543,BC028528,cDNA sequence BC028528,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.2,0.393,10,0,0,-0.1,0.115,-0.115,0.684,0,0,-1.7,1.2
ENSMUSG00000003134,TBC1D8,"TBC1 domain family, member 8",cellular_component|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|calcium ion binding|,10,-0.7,1.04,9,0,0,0.1,0.114,0.114,0.685,0,0,-2,1
ENSMUSG00000056941,COMMD7,COMM domain containing 7,extracellular vesicular exosome|,"negative regulation of NF-kappaB transcription factor activity|tumor necrosis factor-mediated signaling pathway|negative regulation of transcription, DNA-templated|",NF-kappaB binding|,10,0,0,10,0.3,0.349,0.1,0.113,0.113,0.685,0,0,-1.1,1.8
ENSMUSG00000035109,SHC4,"SHC (Src homology 2 domain containing) family, member 4",cellular_component|plasma membrane|membrane|cell junction|synapse|postsynaptic membrane|,apoptotic process|positive regulation of cell proliferation|regulation of gene expression|intracellular signal transduction|stem cell differentiation|,protein domain specific binding|receptor tyrosine kinase binding|,10,0,0,10,0.6,0.81,0.1,0.11,0.11,0.687,0,0,-0.6,2
ENSMUSG00000042616,OSCP1,organic solute carrier partner 1,plasma membrane|membrane|,transport|,None,10,-0.4,1.28,10,0.1,0.1,-0.4,0.11,-0.11,0.687,0,0,-1.6,1.2
ENSMUSG00000027882,STXBP3A,syntaxin binding protein 3A,cell|cytoplasm|cytosol|cytosol|plasma membrane|plasma membrane|membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|platelet alpha granule|specific granule|extracellular vesicular exosome|tertiary granule|,transport|exocytosis|vesicle docking involved in exocytosis|brain development|protein transport|glucose transport|vesicle-mediated transport|protein to membrane docking|insulin secretion|response to insulin|negative regulation of calcium ion-dependent exocytosis|protein heterooligomerization|platelet aggregation|,protein binding|syntaxin-1 binding|syntaxin binding|syntaxin binding|syntaxin binding|,10,0,0,10,0.9,1.13,0.1,0.108,0.108,0.689,0,0,-0.7,2
ENSMUSG00000023289,SVA,seminal vesicle antigen,extracellular space|extracellular space|,cellular response to steroid hormone stimulus|,None,10,0,0,10,-0.1,0.535,-0.1,0.107,-0.107,0.689,0,0,-1.7,1.2
ENSMUSG00000060962,DMKN,dermokine,extracellular region|extracellular space|extracellular vesicular exosome|,biological_process|cell differentiation|,molecular_function|,9,0.5,0.356,10,-0.1,0.217,-0.1,0.107,-0.107,0.689,0,0,-1.5,1.6
ENSMUSG00000018470,KCNAB3,"potassium voltage-gated channel, shaker-related subfamily, beta member 3",cytoplasm|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated potassium channel activity|protein binding|,10,0,0,10,0.2,0.428,0.1,0.105,0.105,0.69,0,0,-1.6,1.4
ENSMUSG00000060791,GMFG,"glia maturation factor, gamma",intracellular|,None,actin binding|growth factor activity|,10,0,0,10,-0.2,0.815,-0.1,0.104,-0.104,0.691,0,0,-1.2,1.7
ENSMUSG00000024940,LTBP3,latent transforming growth factor beta binding protein 3,extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular vesicular exosome|,skeletal system development|transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|negative regulation of bone mineralization|negative regulation of chondrocyte differentiation|transforming growth factor beta activation|positive regulation of bone resorption|bone remodeling|bone morphogenesis|lung saccule development|positive regulation of mesenchymal stem cell proliferation|positive regulation of mesenchymal stem cell differentiation|,calcium ion binding|growth factor binding|transforming growth factor beta binding|,10,0,0,10,0.2,0.297,0.1,0.102,0.102,0.692,0,0,-0.7,2
ENSMUSG00000032609,KLHDC8B,kelch domain containing 8B,cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0.8,0.544,0.1,0.1,0.1,0.693,0,0,-0.9,2
ENSMUSG00000044813,SHB,src homology 2 domain-containing transforming protein B,cellular_component|cytoplasm|plasma membrane|membrane|,angiogenesis|blood vessel development|negative regulation of protein kinase activity|apoptotic process|multicellular organismal development|positive regulation of signal transduction|hemopoiesis|cell differentiation|B cell proliferation|positive regulation of mitotic cell cycle|blood vessel morphogenesis|blood vessel morphogenesis|hematopoietic stem cell proliferation|negative regulation of oocyte maturation|,glycoprotein binding|SH3/SH2 adaptor activity|,10,0.5,1.31,10,0,0,0.1,0.0993,0.0993,0.694,0,0,-0.9,1.9
ENSMUSG00000024935,SLC1A1,"solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|dicarboxylic acid transport|L-glutamate transport|L-glutamate transport|sodium ion transmembrane transport|protein homooligomerization|protein homooligomerization|L-glutamate import|D-aspartate import|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|L-glutamate transmembrane transporter activity|protein binding|symporter activity|glutamate:sodium symporter activity|glutamate:sodium symporter activity|glutamate binding|sodium:dicarboxylate symporter activity|,10,0,0,10,-0.1,0.198,-0.1,0.0978,-0.0978,0.694,0,0,-1.7,1.2
ENSMUSG00000024224,CLPSL2,colipase-like 2,cellular_component|extracellular region|,digestion|biological_process|lipid catabolic process|,molecular_function|enzyme activator activity|,10,0.1,0.228,10,0,0,0.1,0.0972,0.0972,0.695,0,0,-1.2,1.7
ENSMUSG00000067149,IGJ,immunoglobulin joining chain,extracellular region|extracellular space|extracellular vesicular exosome|monomeric IgA immunoglobulin complex|dimeric IgA immunoglobulin complex|dimeric IgA immunoglobulin complex|secretory IgA immunoglobulin complex|secretory dimeric IgA immunoglobulin complex|pentameric IgM immunoglobulin complex|blood microparticle|,adaptive immune response|glomerular filtration|humoral immune response|antibacterial humoral response|positive regulation of protein oligomerization|positive regulation of protein oligomerization|innate immune response|positive regulation of respiratory burst|,single-stranded DNA binding|antigen binding|IgA binding|IgA binding|phosphatidylcholine binding|immunoglobulin receptor binding|immunoglobulin receptor binding|protein homodimerization activity|peptidoglycan binding|,10,0.2,0.551,10,-0.1,0.105,0.1,0.096,0.096,0.696,0,0,-1.3,1.6
ENSMUSG00000022667,CD200R1,CD200 receptor 1,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|receptor complex|,None,receptor activity|protein binding|,10,0.1,0.229,10,0,0,0.1,0.0941,0.0941,0.697,0,0,-1.2,1.7
ENSMUSG00000033763,MTSS1L,metastasis suppressor 1-like,None,signal transduction|filopodium assembly|,actin binding|cytoskeletal adaptor activity|SH3 domain binding|,10,0,0,10,0.1,0.249,0.1,0.0937,0.0937,0.697,0,0,-1.3,1.6
ENSMUSG00000026249,SERPINE2,"serine (or cysteine) peptidase inhibitor, clade E, member 2",extracellular region|extracellular region|extracellular space|extracellular space|cell|cytosol|membrane|extracellular matrix|platelet alpha granule|extrinsic component of external side of plasma membrane|neuromuscular junction|neuronal cell body|,"multicellular organismal development|nervous system development|blood coagulation|negative regulation of cell proliferation|response to wounding|negative regulation of peptidase activity|negative regulation of platelet activation|negative regulation of plasminogen activation|negative regulation of plasminogen activation|negative regulation of sodium ion transport|negative regulation of sodium ion transport|negative regulation of endopeptidase activity|negative regulation of protein processing|positive regulation of neuron projection development|negative regulation of phosphatidylinositol 3-kinase signaling|cerebellar granular layer morphogenesis|cell differentiation|negative regulation of blood coagulation|negative regulation of cell growth|secretion by cell|secretion by cell|secretory granule organization|secretory granule organization|negative regulation of protein catabolic process|negative regulation of protein catabolic process|mating plug formation|negative regulation of proteolysis|negative regulation of smoothened signaling pathway|regulation of timing of cell differentiation|positive regulation of astrocyte differentiation|detection of mechanical stimulus involved in sensory perception|regulation of synaptic transmission, glutamatergic|long-term synaptic potentiation|innervation|seminal vesicle epithelium development|dense core granule biogenesis|negative regulation of platelet aggregation|",serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|receptor binding|receptor binding|glycosaminoglycan binding|heparin binding|peptidase inhibitor activity|,10,0.6,2.22,10,-0.2,0.786,0.2,0.0921,0.0921,0.698,0,0,-0.8,1.9
ENSMUSG00000043183,SIMC1,SUMO-interacting motifs containing 1,cellular_component|,biological_process|,SUMO polymer binding|,10,0,0,10,0.1,0.252,0.1,0.091,0.091,0.699,0,0,-1.2,1.7
ENSMUSG00000030924,2610020H08RIK,RIKEN cDNA 2610020H08 gene,nucleolus|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.1,0.000233,10,-0.7,1.14,0.1,0.089,0.089,0.7,0,0,-1.9,1
ENSMUSG00000093805,GM9994,predicted gene 9994,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0654,10,0.4,1.71,-0.1,0.0869,-0.0869,0.702,0,0,-0.9,2
ENSMUSG00000097886,GM12302,predicted gene 12302,None,None,None,10,-0.1,0.154,10,0.2,0.444,0.1,0.0849,0.0849,0.703,0,0,-1.4,1.5
ENSMUSG00000039262,PRRC2B,proline-rich coiled-coil 2B,cellular_component|,biological_process|,poly(A) RNA binding|,10,0,0,10,-0.4,0.984,0.1,0.0813,0.0813,0.705,0,0,-1.7,1.2
ENSMUSG00000024353,MZB1,marginal zone B and B1 cell-specific protein 1,extracellular region|extracellular region|cytoplasm|endoplasmic reticulum|endoplasmic reticulum lumen|endoplasmic reticulum chaperone complex|,positive regulation of immunoglobulin biosynthetic process|positive regulation of cell proliferation|positive regulation of cell proliferation|regulation of B cell proliferation|integrin activation|regulation of cell proliferation|negative regulation of glucose import in response to insulin stimulus|,protein binding|,10,0.2,0.114,10,0.1,0.0801,0.1,0.0811,0.0811,0.705,0,0,-1.3,1.6
ENSMUSG00000027579,SRMS,src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites,cytoplasm|,protein phosphorylation|phosphorylation|peptidyl-tyrosine autophosphorylation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.14,9,0,0,-0.1,0.0806,-0.0806,0.706,0,0,-1.5,1.5
ENSMUSG00000010911,APIP,APAF1 interacting protein,cellular_component|cytoplasm|,apoptotic process|cellular amino acid biosynthetic process|methionine biosynthetic process|L-methionine salvage from methylthioadenosine|negative regulation of apoptotic process|negative regulation of apoptotic process|regulation of ERK1 and ERK2 cascade|,lyase activity|identical protein binding|methylthioribulose 1-phosphate dehydratase activity|metal ion binding|,10,-0.1,0.235,10,0.1,0.0326,-0.1,0.0792,-0.0792,0.707,0,0,-1.2,1.6
ENSMUSG00000056531,CCDC18,coiled-coil domain containing 18,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.483,0.1,0.0785,0.0785,0.707,0,0,-0.9,1.9
ENSMUSG00000025900,RP1,retinitis pigmentosa 1 (human),photoreceptor outer segment|photoreceptor inner segment|photoreceptor inner segment|cytoplasm|cytoskeleton|microtubule associated complex|cilium|axoneme|photoreceptor connecting cilium|photoreceptor connecting cilium|cell projection|,negative regulation of microtubule depolymerization|visual perception|cell projection organization|axoneme assembly|intracellular signal transduction|photoreceptor cell outer segment organization|photoreceptor cell development|photoreceptor cell maintenance|retinal rod cell development|retinal cone cell development|microtubule polymerization|response to stimulus|retina development in camera-type eye|retina morphogenesis in camera-type eye|cellular response to light stimulus|,microtubule binding|,10,0,0,10,-0.2,0.409,-0.1,0.0773,-0.0773,0.708,0,0,-1.8,1.1
ENSMUSG00000044177,WFIKKN2,"WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2",extracellular region|,skeletal system development|transforming growth factor beta receptor signaling pathway|negative regulation of peptidase activity|negative regulation of protein binding|negative regulation of DNA binding|muscle fiber development|palate development|,enzyme inhibitor activity|serine-type endopeptidase inhibitor activity|protein binding|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,-0.1,0.137,-0.1,0.0753,-0.0753,0.709,0,0,-1.6,1.4
ENSMUSG00000046380,JRK,jerky,nucleus|cytoplasm|ribonucleoprotein complex|,None,nucleic acid binding|DNA binding|mRNA binding|,10,0,0,10,-0.3,0.442,0.1,0.0741,0.0741,0.71,0,0,-1.5,1.4
ENSMUSG00000057738,SPTAN1,"spectrin alpha, non-erythrocytic 1",cytoplasm|cytoskeleton|plasma membrane|fascia adherens|microtubule cytoskeleton|membrane|lateral plasma membrane|Z disc|cortical cytoskeleton|cuticular plate|paranode region of axon|intracellular membrane-bounded organelle|protein complex|extracellular vesicular exosome|,actin cytoskeleton reorganization|actin filament capping|,actin binding|calcium ion binding|calmodulin binding|syntaxin binding|spectrin binding|spectrin binding|spectrin binding|protein complex binding|metal ion binding|protein heterodimerization activity|protein N-terminus binding|,10,0,0,10,-0.2,0.441,-0.1,0.0741,-0.0741,0.71,0,0,-1.5,1.5
ENSMUSG00000070871,CCNYL1,cyclin Y-like 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,1.28,-0.1,0.0713,-0.0713,0.711,0,0,-1.4,1.5
ENSMUSG00000037300,TTC13,tetratricopeptide repeat domain 13,cellular_component|,biological_process|,molecular_function|,10,0.1,0.113,10,0,0,0.1,0.0699,0.0699,0.712,0,0,-1.4,1.6
ENSMUSG00000034083,CCDC174,coiled-coil domain containing 174,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.1,0.406,10,0,0,0.1,0.0688,0.0688,0.713,0,0,-1.7,1.4
ENSMUSG00000078908,MON1B,MON1 homolog b (yeast),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.294,0.1,0.0683,0.0683,0.713,0,0,-1.5,1.4
ENSMUSG00000058935,1700018C11RIK,RIKEN cDNA 1700018C11 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.529,10,0,0,-0.1,0.0652,-0.0652,0.716,0,0,-1.7,1.2
ENSMUSG00000078127,FAM170B,"family with sequence similarity 170, member B",cellular_component|,biological_process|,molecular_function|,10,0.2,0.393,10,0,0,0.1,0.064,0.064,0.716,0,0,-1.7,1.3
ENSMUSG00000030374,STRN4,"striatin, calmodulin binding protein 4",protein phosphatase type 2A complex|cytoplasm|membrane|cell projection|dendritic spine|protein complex|,biological_process|,calmodulin binding|protein domain specific binding|protein complex binding|protein phosphatase 2A binding|armadillo repeat domain binding|,10,0,0,10,0.4,1.13,0.1,0.0546,0.0546,0.722,0,0,-1.1,1.7
ENSMUSG00000040258,NXPH4,neurexophilin 4,cellular_component|,biological_process|,receptor binding|,9,0,0,10,-0.2,0.959,-0.1,0.0526,-0.0526,0.724,0,0,-1.6,1.4
ENSMUSG00000090919,PABPC4L,"poly(A) binding protein, cytoplasmic 4-like",cellular_component|,biological_process|,molecular_function|RNA binding|,10,0,0,10,-0.1,0.46,-0.1,0.0511,-0.0511,0.724,0,0,-1.6,1.4
ENSMUSG00000026523,WDR64,WD repeat domain 64,cellular_component|,biological_process|,molecular_function|,10,0.4,0.0796,10,0.1,0.107,0.2,0.0487,0.0487,0.726,0,0,-0.9,1.8
ENSMUSG00000022780,MFI2,antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5,extracellular region|plasma membrane|cell surface|membrane|anchored component of membrane|anchored component of plasma membrane|extracellular vesicular exosome|,transport|ion transport|iron ion transport|positive regulation of plasminogen activation|iron ion homeostasis|positive regulation of extracellular matrix disassembly|iron ion import|negative regulation of substrate adhesion-dependent cell spreading|,iron ion binding|ferric iron binding|metal ion binding|,10,-0.1,0.0126,10,0.1,0.172,0.1,0.0451,0.0451,0.728,0,0,-1.1,1.7
ENSMUSG00000023805,SYNJ2,synaptojanin 2,cytoplasm|cytoplasmic microtubule|membrane|extrinsic component of mitochondrial outer membrane|ruffle membrane|axon terminus|perinuclear region of cytoplasm|,dephosphorylation|inositol phosphate dephosphorylation|phosphatidylinositol dephosphorylation|intracellular distribution of mitochondria|,"nucleotide binding|nucleic acid binding|RNA binding|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|inositol-polyphosphate 5-phosphatase activity|hydrolase activity|SH3 domain binding|PDZ domain binding|phosphoric ester hydrolase activity|phosphatidylinositol monophosphate phosphatase activity|",10,0,0,10,0.4,0.7,0.1,0.0372,0.0372,0.733,0,0,-1.6,1.4
ENSMUSG00000038541,SRD5A2,steroid 5 alpha-reductase 2,cytoplasm|endoplasmic reticulum|membrane|integral component of membrane|neuronal cell body|intracellular membrane-bounded organelle|cell body fiber|,lipid metabolic process|steroid biosynthetic process|steroid biosynthetic process|androgen biosynthetic process|androgen biosynthetic process|steroid catabolic process|sex differentiation|steroid metabolic process|androgen metabolic process|male gonad development|response to organic substance|cell differentiation|male genitalia development|response to peptide hormone|oxidation-reduction process|,"3-oxo-5-alpha-steroid 4-dehydrogenase activity|3-oxo-5-alpha-steroid 4-dehydrogenase activity|sterol 5-alpha reductase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-CH group of donors|amide binding|cholestenone 5-alpha-reductase activity|",10,0,0,10,0.1,0.24,0.1,0.0369,0.0369,0.733,0,0,-0.9,2
ENSMUSG00000023572,CCNDBP1,cyclin D-type binding-protein 1,nucleus|cytoplasm|,cell cycle|regulation of cell cycle|,None,10,0,0,10,0.5,0.381,-0.1,0.0357,-0.0357,0.734,0,0,-1.2,1.7
ENSMUSG00000031637,LRP2BP,Lrp2 binding protein,cytoplasm|,biological_process|,protein binding|,10,0,0,10,-0.1,0.0575,-0.1,0.0356,-0.0356,0.734,0,0,-1.6,1.4
ENSMUSG00000042684,NPL,N-acetylneuraminate pyruvate lyase,cellular_component|cytoplasm|,carbohydrate metabolic process|metabolic process|N-acetylneuraminate catabolic process|,catalytic activity|N-acetylneuraminate lyase activity|N-acetylneuraminate lyase activity|lyase activity|,10,-0.1,0.602,10,0.3,0.89,-0.1,0.0336,-0.0336,0.735,0,0,-1.2,1.6
ENSMUSG00000074637,SOX2,SRY (sex determining region Y)-box 2,nucleus|nucleus|nucleus|transcription factor complex|cytoplasm|cytoplasm|cytosol|nuclear transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|osteoblast differentiation|cell fate specification|endodermal cell fate specification|positive regulation of neuroblast proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|cell cycle arrest|multicellular organismal development|sensory perception of sound|response to organic substance|regulation of gene expression|stem cell maintenance|forebrain neuron differentiation|adenohypophysis development|cerebral cortex development|positive regulation of cell-cell adhesion|negative regulation of Wnt signaling pathway|male genitalia development|positive regulation of epithelial cell differentiation|olfactory placode formation|response to retinoic acid|somatic stem cell maintenance|inner ear morphogenesis|regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of MAPK cascade|tongue development|cell fate commitment|negative regulation of cell differentiation|positive regulation of cell differentiation|negative regulation of neuron differentiation|positive regulation of neuron differentiation|negative regulation of osteoblast differentiation|positive regulation of Notch signaling pathway|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|pigment biosynthetic process|lung alveolus development|embryonic organ development|anatomical structure formation involved in morphogenesis|neuron fate commitment|diencephalon morphogenesis|stem cell differentiation|negative regulation of epithelial cell proliferation|regulation of neurogenesis|detection of mechanical stimulus involved in sensory perception of sound|detection of mechanical stimulus involved in equilibrioception|retina morphogenesis in camera-type eye|lens induction in camera-type eye|epithelial tube branching involved in lung morphogenesis|response to growth factor|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|neuronal stem cell maintenance|",transcription regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|miRNA binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0,0,10,0.1,0.0578,0.1,0.0288,0.0288,0.739,0,0,-1.3,1.6
ENSMUSG00000022265,ANK,progressive ankylosis,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|integral component of membrane|,transport|phosphate ion transport|regulation of bone mineralization|inorganic diphosphate transport|inorganic diphosphate transport|ion transmembrane transport|phosphate ion transmembrane transport|,inorganic phosphate transmembrane transporter activity|phosphate ion transmembrane transporter activity|inorganic diphosphate transmembrane transporter activity|inorganic diphosphate transmembrane transporter activity|,10,0,0,10,-0.1,0.18,-0.1,0.0277,-0.0277,0.739,0,0,-1.1,1.8
ENSMUSG00000020844,NXN,nucleoredoxin,nucleus|cytoplasm|,multicellular organismal development|Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|negative regulation of protein ubiquitination|oxidation-reduction process|cardiovascular system development|,thioredoxin-disulfide reductase activity|protein binding|oxidoreductase activity|protein-disulfide reductase activity|,10,-0.7,1.53,10,0.2,0.223,0.1,0.027,0.027,0.74,0,0,-1.9,1.1
ENSMUSG00000028068,IQGAP3,IQ motif containing GTPase activating protein 3,intracellular|cytoplasm|cell-cell junction|lateral plasma membrane|,G1/S transition of mitotic cell cycle|activation of MAPK activity|positive regulation of protein phosphorylation|Ras protein signal transduction|regulation of cell size|positive regulation of gene expression|negative regulation of gene expression|positive regulation of mammary gland epithelial cell proliferation|ERK1 and ERK2 cascade|cellular response to organic substance|,protein binding|Ras GTPase binding|Rho GTPase binding|,10,0,0,10,0.1,0.0786,0.1,0.0265,0.0265,0.74,0,0,-1.4,1.7
ENSMUSG00000047221,FAM185A,"family with sequence similarity 185, member A",None,biological_process|,molecular_function|,10,0,0,10,-0.2,0.259,-0.1,0.0263,-0.0263,0.74,0,0,-1.8,1.1
ENSMUSG00000055302,MRFAP1,Morf4 family associated protein 1,cellular_component|nucleus|cytoplasm|,biological_process|,protein binding|,4,0.2,0.377,4,0,0,0.1,0.0256,0.0256,0.741,0,0,-1.6,1.9
ENSMUSG00000094410,ZBED6,"zinc finger, BED domain containing 6",nucleus|nucleolus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|metal ion binding|protein dimerization activity|,10,0,0,10,-0.1,0.1,-0.1,0.0241,-0.0241,0.741,0,0,-1.4,1.5
ENSMUSG00000052906,UBXN8,UBX domain protein 8,endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,ER-associated ubiquitin-dependent protein catabolic process|,molecular_function|,10,0,0,10,0.1,0.061,0.1,0.0211,0.0211,0.743,0,0,-1.4,1.6
ENSMUSG00000044576,GAREML,"GRB2 associated, regulator of MAPK1-like",extracellular vesicular exosome|,biological_process|,molecular_function|,9,0,0,9,0.1,0.112,0.1,0.0194,0.0194,0.744,0,0,-1.2,1.8
ENSMUSG00000072704,2700089E24RIK,RIKEN cDNA 2700089E24 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.7,1.08,0.1,0.0172,0.0172,0.746,0,0,-0.7,2
ENSMUSG00000032514,TTC21A,tetratricopeptide repeat domain 21A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,1.85,0.2,0.0168,0.0168,0.746,0,0,-0.6,2
ENSMUSG00000047466,8030462N17RIK,RIKEN cDNA 8030462N17 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.257,0.1,0.0156,0.0156,0.747,0,0,-1.2,1.7
ENSMUSG00000000531,GRASP,GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein,nuclear envelope lumen|cytoplasm|plasma membrane|plasma membrane|membrane|,intracellular protein transport|signal transduction|protein localization|,protein binding|PDZ domain binding|ADP-ribosylation factor binding|identical protein binding|,9,0,0,9,0.2,0.143,0.1,0.0148,0.0148,0.747,0,0,-1.2,1.8
ENSMUSG00000033526,PPIP5K1,diphosphoinositol pentakisphosphate kinase 1,cytoplasm|cytosol|plasma membrane|membrane|,inositol metabolic process|phosphorylation|,"nucleotide binding|inositol-1,3,4,5,6-pentakisphosphate kinase activity|inositol hexakisphosphate 5-kinase activity|acid phosphatase activity|ATP binding|kinase activity|transferase activity|diphosphoinositol-pentakisphosphate kinase activity|inositol hexakisphosphate 1-kinase activity|inositol hexakisphosphate 3-kinase activity|",10,0,0,10,0.3,0.681,0.1,0.012,0.012,0.749,0,0,-1.2,1.7
ENSMUSG00000042763,MANEAL,"mannosidase, endo-alpha-like",cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,-0.1,0.0595,10,-0.7,0.436,-0.1,0.0116,-0.0116,0.749,0,0,-1.9,0.9
ENSMUSG00000059455,PLAC8L1,PLAC8-like 1,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.788,10,0,0,-0.1,0.00553,-0.00553,0.753,0,0,-1.8,1.1
ENSMUSG00000096603,GM7694,predicted gene 7694,cellular_component|,biological_process|,molecular_function|,10,-0.8,0.533,10,0,0,-0.1,0.00518,-0.00518,0.753,0,0,-2,0.9
ENSMUSG00000028256,ODF2L,outer dense fiber of sperm tails 2-like,centrosome|,biological_process|,molecular_function|,10,-0.1,0.0493,10,0,0,-0.1,0.00484,-0.00484,0.753,0,0,-1.8,1.2
ENSMUSG00000022421,NPTXR,neuronal pentraxin receptor,extracellular space|plasma membrane|,signal transduction|,pentraxin receptor activity|protein complex binding|,6,0.3,0.606,6,0,0,0.1,0.0048,0.0048,0.754,0,0,-1.2,2
ENSMUSG00000038276,ASIC3,acid-sensing (proton-gated) ion channel 3,cytoplasm|plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|cation transport|cation transport|sodium ion transport|response to heat|response to mechanical stimulus|response to acidity|response to acidity|response to acidity|ion transmembrane transport|ion transmembrane transport|sodium ion transmembrane transport|enterobactin transport|detection of chemical stimulus involved in sensory perception|sensory perception of sour taste|detection of temperature stimulus involved in sensory perception|detection of temperature stimulus involved in sensory perception of pain|detection of mechanical stimulus involved in sensory perception of pain|detection of chemical stimulus involved in sensory perception of pain|detection of mechanical stimulus involved in sensory perception|,cation channel activity|cation channel activity|cation channel activity|sodium channel activity|ligand-gated sodium channel activity|PDZ domain binding|enterobactin transporter activity|,10,0,0,10,0.1,0.126,0.1,0.0029,0.0029,0.755,0,0,-1.2,2
ENSMUSG00000070604,VSIG10L,ZV-set and immunoglobulin domain containing 10 like,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.79,10,0,0,0.1,0.00173,0.00173,0.755,0,0,-1.2,1.7
ENSMUSG00000079652,FAM71F2,"family with sequence similarity 71, member F2",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0262,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000020778,TEN1,TEN1 telomerase capping complex subunit,"chromosome, telomeric region|nuclear chromosome, telomeric region|nuclear chromosome, telomeric region|nucleus|nucleus|chromosome|Stn1-Ten1 complex|",biological_process|,molecular_function|DNA binding|single-stranded DNA binding|,9,0.2,0.506,9,-0.8,1.89,0,0,0,0.756,0,0,-2,0.9
ENSMUSG00000018900,SLC22A5,"solute carrier family 22 (organic cation transporter), member 5",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|brush border membrane|brush border membrane|extracellular vesicular exosome|,amino acid transmembrane transport|transport|ion transport|sodium ion transport|mitochondrion organization|adult heart development|locomotory behavior|carnitine metabolic process|organic cation transport|quaternary ammonium group transport|quaternary ammonium group transport|carnitine transport|carnitine transport|carnitine transport|ion transmembrane transport|antibiotic transport|reproductive structure development|quorum sensing involved in interaction with host|transmembrane transport|positive regulation of intestinal epithelial structure maintenance|sodium-dependent organic cation transport|modified amino acid transport|carnitine transmembrane transport|carnitine transmembrane transport|,nucleotide binding|transporter activity|ATP binding|ion transmembrane transporter activity|carnitine transmembrane transporter activity|carnitine transmembrane transporter activity|carnitine transmembrane transporter activity|symporter activity|quaternary ammonium group transmembrane transporter activity|quaternary ammonium group transmembrane transporter activity|transmembrane transporter activity|PDZ domain binding|antibiotic transporter activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000030402,PPM1N,"protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)",cellular_component|,biological_process|,magnesium ion binding|molecular_function|catalytic activity|phosphoprotein phosphatase activity|hydrolase activity|manganese ion binding|metal ion binding|,10,0.1,0.295,10,-1,1.2,0,0,0,0.756,0,0,-2,1
ENSMUSG00000041406,BC055324,cDNA sequence BC055324,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.0647,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000031109,ENOX2,ecto-NOX disulfide-thiol exchanger 2,extracellular region|plasma membrane|external side of plasma membrane|membrane|,transport|ultradian rhythm|regulation of growth|rhythmic process|oxidation-reduction process|,nucleotide binding|nucleic acid binding|N-ethylmaleimide reductase activity|protein disulfide oxidoreductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.3,0.155,10,0,0,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000020834,DHRS13,dehydrogenase/reductase (SDR family) member 13,extracellular region|membrane|,metabolic process|oxidation-reduction process|,"oxidoreductase activity|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|versicolorin reductase activity|ketoreductase activity|",10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000028795,CCDC28B,coiled coil domain containing 28B,cytoplasm|centrosome|cytoskeleton|,cell projection organization|cilium assembly|,molecular_function|,10,-0.1,0.0287,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000028545,BEND5,BEN domain containing 5,Golgi apparatus|,biological_process|,molecular_function|,9,-0.1,0.186,9,0,0,0,0,0,0.756,0,0,-1.8,1.3
ENSMUSG00000027007,SSFA2,sperm specific antigen 2,nucleus|cytoplasm|plasma membrane|,None,actin binding|receptor binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000033257,TTLL4,"tubulin tyrosine ligase-like family, member 4",cellular_component|cytoplasm|cytoskeleton|cilium|cell projection|,cellular protein modification process|protein polyglutamylation|,tubulin binding|ligase activity|,10,0,0,10,0.2,0.335,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000063060,SOX7,SRY (sex determining region Y)-box 7,nucleus|nucleus|cytoplasm|cytoplasm|,"endoderm formation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|negative regulation of cell proliferation|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|regulation of canonical Wnt signaling pathway|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|transcription regulatory region DNA binding|,10,-0.8,2.03,10,0,0,0,0,0,0.756,0,0,-2,0.6
ENSMUSG00000054708,ANKRD24,ankyrin repeat domain 24,cellular_component|,biological_process|,protein binding|,10,0.1,0.0971,10,0,0,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000039693,MSANTD3,Myb/SANT-like DNA-binding domain containing 3,cellular_component|,biological_process|,identical protein binding|,10,-0.2,0.576,10,0.7,1.15,0,0,0,0.756,0,0,-1.2,1.9
ENSMUSG00000042106,FAM212A,"family with sequence similarity 212, member A",extracellular vesicular exosome|,neural tube development|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000037355,UVSSA,UV stimulated scaffold protein A,chromosome|,DNA repair|transcription-coupled nucleotide-excision repair|cellular response to DNA damage stimulus|response to UV|protein ubiquitination|,RNA polymerase II core binding|,10,-0.1,0.0544,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000062604,SRPK2,serine/arginine-rich protein specific kinase 2,nucleus|nucleus|cytoplasm|cytoplasm|,spliceosomal complex assembly|spliceosomal complex assembly|angiogenesis|mRNA processing|protein phosphorylation|protein phosphorylation|positive regulation of cell proliferation|positive regulation of cell proliferation|RNA splicing|RNA splicing|positive regulation of gene expression|phosphorylation|cell differentiation|nuclear speck organization|intracellular signal transduction|intracellular signal transduction|positive regulation of neuron apoptotic process|positive regulation of viral genome replication|negative regulation of viral genome replication|positive regulation of cell cycle|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|14-3-3 protein binding|",10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000060147,SERPINB6A,"serine (or cysteine) peptidase inhibitor, clade B, member 6a",extracellular space|intracellular|cytoplasm|cytoplasm|protein complex|extracellular vesicular exosome|,gonad development|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,protease binding|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|protein binding|peptidase inhibitor activity|,10,0,0,10,-0.2,0.394,0,0,0,0.756,0,0,-1,2
ENSMUSG00000029641,RASL11A,"RAS-like, family 11, member A",nucleus|nucleolus|membrane|,"GTP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|small GTPase mediated signal transduction|positive regulation of transcription from RNA polymerase I promoter|",nucleotide binding|protein binding|GTP binding|,10,-0.2,0.664,10,0.2,0.552,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000046959,SLC26A1,"solute carrier family 26 (sulfate transporter), member 1",membrane|integral component of membrane|,transport|ion transport|chloride transport|sulfate transport|sulfate transport|oxalate transport|transmembrane transport|sulfate transmembrane transport|sulfate transmembrane transport|chloride transmembrane transport|,secondary active sulfate transmembrane transporter activity|chloride transmembrane transporter activity|sulfate transmembrane transporter activity|sulfate transmembrane transporter activity|antiporter activity|anion:anion antiporter activity|oxalate transmembrane transporter activity|,10,0,0,10,-0.6,0.407,0,0,0,0.756,0,0,-1.9,1.1
ENSMUSG00000042918,MAMSTR,MEF2 activating motif and SAP domain containing transcriptional regulator,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of myotube differentiation|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription factor binding transcription factor activity|nucleic acid binding|protein binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000047423,AI837181,expressed sequence AI837181,cellular_component|,biological_process|,poly(A) RNA binding|,10,0.1,0.121,10,0,0,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000022012,ENOX1,ecto-NOX disulfide-thiol exchanger 1,extracellular region|plasma membrane|membrane|,transport|biological_process|rhythmic process|oxidation-reduction process|,nucleotide binding|molecular_function|nucleic acid binding|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000090066,1110002E22RIK,RIKEN cDNA 1110002E22 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.183,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000022428,CBY1,chibby homolog 1 (Drosophila),nucleus|Golgi apparatus|trans-Golgi network|ciliary basal body|,"protein localization|cell differentiation|negative regulation of Wnt signaling pathway|cilium assembly|fat cell differentiation|negative regulation of transcription, DNA-templated|cardiac muscle cell differentiation|negative regulation of canonical Wnt signaling pathway|",beta-catenin binding|identical protein binding|,10,0.1,0.0541,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000023052,NPFF,neuropeptide FF-amide peptide precursor,extracellular region|extracellular space|dendrite|vesicle|perikaryon|axon terminus|,regulation of membrane depolarization|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|negative regulation of heart rate|vasopressin secretion|negative regulation of appetite|positive regulation of blood pressure|negative regulation of insulin secretion|regulation of sensory perception of pain|regulation of excitatory postsynaptic membrane potential|somatostatin secretion|,G-protein coupled receptor binding|neuropeptide hormone activity|,10,0,0,10,-0.2,0.134,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000079592,C1QTNF5,C1q and tumor necrosis factor related protein 5,extracellular region|extracellular space|cell|plasma membrane|tight junction|membrane|apical plasma membrane|lateral plasma membrane|transport vesicle|cell projection|extracellular vesicular exosome|,protein secretion|inner ear development|protein trimerization|,identical protein binding|,10,0.1,0.0788,10,1.3,0.518,0,0,0,0.756,0,0,-0.9,2
ENSMUSG00000024039,CBS,cystathionine beta-synthase,nucleus|cytoplasm|cytosol|,endochondral ossification|blood vessel remodeling|cysteine biosynthetic process from serine|superoxide metabolic process|cellular amino acid biosynthetic process|cysteine biosynthetic process via cystathionine|cysteine biosynthetic process|transsulfuration|cerebellum morphogenesis|regulation of cGMP metabolic process|negative regulation of apoptotic process|regulation of JUN kinase activity|homocysteine metabolic process|homocysteine metabolic process|regulation of blood vessel size|response to folic acid|maternal process involved in female pregnancy|cartilage development involved in endochondral bone morphogenesis|hydrogen sulfide biosynthetic process|cellular response to hypoxia|,cystathionine beta-synthase activity|cystathionine beta-synthase activity|lyase activity|enzyme binding|heme binding|pyridoxal phosphate binding|adenyl nucleotide binding|ubiquitin protein ligase binding|identical protein binding|protein homodimerization activity|metal ion binding|modified amino acid binding|,10,-0.1,0.0113,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000041396,METTL18,methyltransferase like 18,cellular_component|cytoplasm|,protein methylation|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,0,0,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000084989,E030010N08RIK,RIKEN cDNA E030010N08 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-1.1,0.646,0,0,0,0.756,0,0,-2,1
ENSMUSG00000041930,FAM222A,"family with sequence similarity 222, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0924,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000053012,KRCC1,lysine-rich coiled-coil 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.201,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000053550,SHISA7,shisa family member 7,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,0.0925,10,0.1,0.0828,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000047356,LCN10,lipocalin 10,cellular_component|extracellular region|,transport|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000053684,BC048403,cDNA sequence BC048403,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.292,0,0,0,0.756,0,0,-1,2
ENSMUSG00000051502,UFSP1,UFM1-specific peptidase 1,extracellular vesicular exosome|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|thiolester hydrolase activity|UFM1 hydrolase activity|UFM1 hydrolase activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000046337,FAM178B,"family with sequence similarity 178, member B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.323,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000039512,UHRF1BP1,UHRF1 (ICBP90) binding protein 1,cellular_component|,biological_process|,identical protein binding|histone deacetylase binding|,10,0,0,10,0.1,0.209,0,0,0,0.756,0,0,-1.1,2
ENSMUSG00000042510,AA986860,expressed sequence AA986860,cytoplasm|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.1,0.0926,10,0,0,0,0,0,0.756,0,0,-1.8,1.1
ENSMUSG00000012211,TEX22,testis expressed gene 22,acrosomal vesicle|cytoplasm|cytoplasmic vesicle|,biological_process|,molecular_function|,10,-0.1,0.282,10,0.2,0.366,0,0,0,0.756,0,0,-1,1.9
ENSMUSG00000042821,SNAI1,snail family zinc finger 1,nucleus|nucleus|cytoplasm|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|mesoderm formation|epithelial to mesenchymal transition|epithelial to mesenchymal transition|epithelial to mesenchymal transition|epithelial to mesenchymal transition involved in endocardial cushion formation|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|mesoderm development|positive regulation of epithelial to mesenchymal transition|positive regulation of epithelial to mesenchymal transition|negative regulation of vitamin D biosynthetic process|cell migration|positive regulation of cell migration|positive regulation of cell migration|hair follicle morphogenesis|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|palate development|cartilage morphogenesis|trophoblast giant cell differentiation|negative regulation of cell differentiation involved in embryonic placenta development|left/right pattern formation|Notch signaling involved in heart development|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|regulation of tight junction assembly|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|protein binding|kinase binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1,1.9
ENSMUSG00000047671,TCTEX1D4,Tctex1 domain containing 4,acrosomal vesicle|nucleus|cytoplasm|microtubule organizing center|axoneme|sperm flagellum|,biological_process|,protein phosphatase 1 binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000023931,EFHB,"EF hand domain family, member B",cellular_component|,biological_process|,calcium ion binding|metal ion binding|,10,-0.5,0.626,10,0,0,0,0,0,0.756,0,0,-1.7,1.3
ENSMUSG00000074457,S100A16,S100 calcium binding protein A16,nucleus|nucleolus|cytoplasm|cytoplasm|cytosol|plasma membrane|extracellular vesicular exosome|,response to calcium ion|,calcium ion binding|calcium ion binding|protein homodimerization activity|protein homodimerization activity|poly(A) RNA binding|metal ion binding|,10,0.1,0.26,10,0,0,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000030301,CCDC91,coiled-coil domain containing 91,nucleus|Golgi apparatus|membrane|,transport|biological_process|protein transport|,identical protein binding|,10,-0.1,0.217,10,0.1,0.484,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000046203,SPRR2G,small proline-rich protein 2G,None,None,None,10,0,0,10,-0.2,0.381,0,0,0,0.756,0,0,-1.8,1.3
ENSMUSG00000038056,KMT2C,lysine (K)-specific methyltransferase 2C,nucleus|histone methyltransferase complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone methylation|peptidyl-lysine methylation|methylation|intracellular signal transduction|histone H3-K4 methylation|",DNA binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H3-K4 specific)|poly(A) RNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000026080,CHST10,carbohydrate sulfotransferase 10,Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|learning|long-term memory|carbohydrate biosynthetic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0,0,10,0.1,0.0175,0,0,0,0.756,0,0,-2,1.1
ENSMUSG00000044465,FAM160A2,"family with sequence similarity 160, member A2",FHF complex|,transport|endosome organization|lysosome organization|endosome to lysosome transport|protein transport|early endosome to late endosome transport|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000024043,ARHGAP28,Rho GTPase activating protein 28,intracellular|nucleus|cell junction|,signal transduction|,molecular_function|GTPase activator activity|,10,0,0,10,-0.1,0.315,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000028990,LZIC,leucine zipper and CTNNBIP1 domain containing,cellular_component|,None,molecular_function|beta-catenin binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1,1.9
ENSMUSG00000035208,SLFN8,schlafen 8,intracellular|,biological_process|,molecular_function|,10,-0.1,0.234,10,0.2,0.871,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000024354,SLC23A1,"solute carrier family 23 (nucleobase transporters), member 1",cytoplasm|cytoplasm|plasma membrane|brush border|basal plasma membrane|basal plasma membrane|membrane|integral component of membrane|apical plasma membrane|intracellular organelle|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|brain development|response to toxic substance|L-ascorbic acid transport|L-ascorbic acid transport|L-ascorbic acid transport|lung development|carbohydrate transmembrane transport|vitamin transmembrane transport|sodium ion transmembrane transport|transmembrane transport|dehydroascorbic acid transport|transepithelial L-ascorbic acid transport|,transporter activity|L-ascorbate:sodium symporter activity|sodium ion transmembrane transporter activity|L-ascorbic acid transporter activity|L-ascorbic acid transporter activity|L-ascorbic acid transporter activity|symporter activity|dehydroascorbic acid transporter activity|sodium-dependent L-ascorbate transmembrane transporter activity|,10,0,0,10,0.5,0.71,0,0,0,0.756,0,0,-1.1,1.8
ENSMUSG00000028331,5830415F09RIK,RIKEN cDNA 5830415F09 gene,cellular_component|,biological_process|,"molecular_function|CoA hydrolase activity|hydrolase activity|2-oxoglutaryl-CoA thioesterase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity|3-isopropylbut-3-enoyl-CoA thioesterase activity|glutaryl-CoA hydrolase activity|acyl-CoA hydrolase activity|",10,0,0,9,0.1,0.357,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000050910,CDR2L,cerebellar degeneration-related protein 2-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000028962,SLC4A2,"solute carrier family 4 (anion exchanger), member 2",membrane|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|,transport|ion transport|anion transport|chloride transport|chloride transmembrane transport|,transporter activity|inorganic anion exchanger activity|anion transmembrane transporter activity|chloride transmembrane transporter activity|antiporter activity|anion:anion antiporter activity|,10,0.1,0.142,10,1.3,0.441,0,0,0,0.756,0,0,-0.8,2
ENSMUSG00000022408,FAM83F,"family with sequence similarity 83, member F",cellular_component|,biological_process|,molecular_function|,10,0.1,0.182,10,0,0,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000026600,SOAT1,sterol O-acyltransferase 1,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,lipid metabolic process|steroid metabolic process|cholesterol metabolic process|cholesterol metabolic process|macrophage derived foam cell differentiation|cholesterol storage|cholesterol efflux|very-low-density lipoprotein particle assembly|cholesterol esterification|positive regulation of amyloid precursor protein biosynthetic process|,"fatty-acyl-CoA binding|sterol O-acyltransferase activity|sterol O-acyltransferase activity|O-acyltransferase activity|cholesterol binding|transferase activity|transferase activity, transferring acyl groups|cholesterol O-acyltransferase activity|",10,0,0,10,0,0,0,0,0,0.756,0,0,-1.9,1.1
ENSMUSG00000004837,GRAP,GRB2-related adaptor protein,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.00676,10,0,0,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000022676,SNAI2,snail family zinc finger 2,nuclear chromatin|nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|epithelial to mesenchymal transition|epithelial to mesenchymal transition|epithelial to mesenchymal transition involved in endocardial cushion formation|cell migration involved in endocardial cushion formation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|negative regulation of cell adhesion involved in substrate-bound cell migration|Notch signaling pathway|multicellular organismal development|sensory perception of sound|sensory perception of sound|response to radiation|response to radiation|negative regulation of keratinocyte proliferation|negative regulation of vitamin D biosynthetic process|neural crest cell development|cell migration|positive regulation of cell migration|negative regulation of chondrocyte differentiation|regulation of chemokine production|positive regulation of histone acetylation|negative regulation of catenin import into nucleus|desmosome disassembly|desmosome disassembly|cellular response to platelet-derived growth factor stimulus|regulation of apoptotic process|negative regulation of apoptotic process|pigmentation|pigmentation|negative regulation of DNA damage response, signal transduction by p53 class mediator|wound healing, spreading of cells|positive regulation of fat cell differentiation|positive regulation of fat cell differentiation|regulation of osteoblast differentiation|white fat cell differentiation|palate development|palate development|canonical Wnt signaling pathway|epithelium development|cartilage morphogenesis|regulation of branching involved in salivary gland morphogenesis|negative regulation of vitamin D receptor signaling pathway|cellular response to epidermal growth factor stimulus|cellular response to ionizing radiation|negative regulation of canonical Wnt signaling pathway|negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|negative regulation of stem cell proliferation|regulation of tight junction assembly|negative regulation of anoikis|positive regulation of endothelial cell chemotaxis|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|",RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|chromatin binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|metal ion binding|,10,0,0,10,-0.1,0.0246,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000030134,RASGEF1A,"RasGEF domain family, member 1A",cellular_component|,cell migration|positive regulation of Ras GTPase activity|positive regulation of Ras protein signal transduction|,guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|,10,0,0,10,-0.5,1.33,0,0,0,0.756,0,0,-2,0.9
ENSMUSG00000067297,2010002M12RIK,RIKEN cDNA 2010002M12 gene,extracellular region|cytoplasm|host cell|,response to virus|intracellular transport of viral protein in host cell|negative regulation of protein binding|positive regulation of viral genome replication|negative regulation of viral genome replication|negative regulation of defense response to virus by host|negative regulation of helicase activity|cellular response to type I interferon|cellular response to exogenous dsRNA|,RNA binding|,10,0.2,0.199,10,0,0,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000025963,MDH1B,"malate dehydrogenase 1B, NAD (soluble)",cellular_component|,carbohydrate metabolic process|tricarboxylic acid cycle|malate metabolic process|oxidation-reduction process|,"C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity|catalytic activity|aldo-keto reductase (NADP) activity|isocitrate dehydrogenase activity|mevaldate reductase activity|gluconate dehydrogenase activity|steroid dehydrogenase activity|oxidoreductase activity|malate dehydrogenase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|epoxide dehydrogenase activity|5-exo-hydroxycamphor dehydrogenase activity|2-hydroxytetrahydrofuran dehydrogenase activity|acetoin dehydrogenase activity|phenylcoumaran benzylic ether reductase activity|D-xylose:NADP reductase activity|L-arabinose:NADP reductase activity|D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity|steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|steroid dehydrogenase activity, acting on the CH-CH group of donors|(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity|3-hydroxymenthone dehydrogenase activity|very long-chain-3-hydroxyacyl-CoA dehydrogenase activity|dihydrotestosterone 17-beta-dehydrogenase activity|(R)-2-hydroxyisocaproate dehydrogenase activity|L-arabinose 1-dehydrogenase (NADP+) activity|L-xylulose reductase (NAD+) activity|3-ketoglucose-reductase activity|(R)-2-hydroxyglutarate dehydrogenase activity|D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity|",10,0.2,0.342,10,-0.1,0.00221,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000059479,B3GNT8,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8",cellular_component|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|poly-N-acetyllactosamine biosynthetic process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|protein N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000045275,LCA5L,Leber congenital amaurosis 5-like,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0627,10,0.2,0.277,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000048647,EXD1,exonuclease 3'-5' domain containing 1,cellular_component|,nucleobase-containing compound metabolic process|biological_process|,nucleic acid binding|nuclease activity|exonuclease activity|3'-5' exonuclease activity|hydrolase activity|,10,0,0,10,0.1,0.0138,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000039765,CC2D2A,coiled-coil and C2 domain containing 2A,cytoplasm|cytoskeleton|cilium|ciliary transition zone|TCTN-B9D complex|cell projection|,smoothened signaling pathway|cell projection organization|cilium assembly|cilium morphogenesis|,protein binding|,10,0,0,10,0.4,0.42,0,0,0,0.756,0,0,-1.1,1.8
ENSMUSG00000048997,ATXN7L2,ataxin 7-like 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.408,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000042272,SESTD1,SEC14 and spectrin domains 1,calcium channel complex|,None,"phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-5-phosphate binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-3,4-bisphosphate binding|phosphatidylinositol-4-phosphate binding|phosphatidic acid binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0,0,10,0.2,0.316,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000059112,OLFR1263,olfactory receptor 1263,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,0.049,10,0.7,0.456,0,0,0,0.756,0,0,-0.7,1.9
ENSMUSG00000066233,TMEM42,transmembrane protein 42,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.193,10,0.1,0.049,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000036216,LEAP2,liver-expressed antimicrobial peptide 2,extracellular region|,defense response to bacterium|,None,10,0,0,10,0.1,0.166,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000032352,LRRC1,leucine rich repeat containing 1,cytoplasm|membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000008129,4930432K21RIK,RIKEN cDNA 4930432K21 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.121,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000079084,CCDC82,coiled-coil domain containing 82,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0669,0,0,0,0.756,0,0,-1.7,1.2
ENSMUSG00000053091,LINS,lines homolog (Drosophila),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.409,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000036598,CCDC113,coiled-coil domain containing 113,nucleus|cytoplasm|protein complex|,biological_process|,molecular_function|,10,0.1,0.118,10,0,0,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000030606,HAPLN3,hyaluronan and proteoglycan link protein 3,extracellular region|proteinaceous extracellular matrix|extracellular space|,cell adhesion|biological_process|,hyaluronic acid binding|,10,-0.1,0.109,10,0.1,0.207,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000071855,CCDC112,coiled-coil domain containing 112,cellular_component|,biological_process|,molecular_function|,10,0.5,0.566,10,-0.1,0.0972,0,0,0,0.756,0,0,-0.9,1.9
ENSMUSG00000042564,FAM227A,"family with sequence similarity 227, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.127,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000036918,TTC7,tetratricopeptide repeat domain 7,None,cellular iron ion homeostasis|hemopoiesis|,None,10,-0.7,1.27,10,0.1,0.0937,0,0,0,0.756,0,0,-1.5,1.9
ENSMUSG00000000958,SLC7A7,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 7",plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|amino acid transport|,amino acid transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000024219,ANKS1,ankyrin repeat and SAM domain containing 1,nucleus|cytoplasm|,regulation of ephrin receptor signaling pathway|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|,ephrin receptor binding|,9,0,0,9,-0.4,0.375,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000001054,RMND5B,required for meiotic nuclear division 5 homolog B (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.187,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000074579,LEKR1,"leucine, glutamate and lysine rich 1",cellular_component|,biological_process|,molecular_function|,10,0.1,0.0482,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000050092,SPRR2B,small proline-rich protein 2B,cornified envelope|cytoplasm|,epidermis development|keratinocyte differentiation|keratinization|response to estradiol|,molecular_function|,10,0.1,0.253,10,-0.1,0.00356,0,0,0,0.756,0,0,-2,0.9
ENSMUSG00000078552,DCDC2B,doublecortin domain containing 2b,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0328,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000035212,LEPROT,leptin receptor overlapping transcript,endosome|Golgi apparatus|membrane|integral component of membrane|,negative regulation of JAK-STAT cascade|negative regulation of growth hormone receptor signaling pathway|negative regulation of protein localization to cell surface|,receptor binding|protein binding|,9,0,0,9,0,0,0,0,0,0.756,0,0,-1.5,1.7
ENSMUSG00000001436,SLC19A1,"solute carrier family 19 (folate transporter), member 1",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|brush border membrane|,transport|folic acid transport|methotrexate transport|transmembrane transport|,folic acid binding|folic acid transporter activity|reduced folate carrier activity|methotrexate transporter activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000002475,ABHD3,abhydrolase domain containing 3,cellular_component|membrane|integral component of membrane|,biological_process|,"phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.1,0.364,10,0,0,0,0,0,0.756,0,0,-0.9,2
ENSMUSG00000031755,BBS2,Bardet-Biedl syndrome 2 (human),cytoplasm|cytoskeleton|plasma membrane|cilium|membrane|motile cilium|motile cilium|BBSome|BBSome|ciliary basal body|cell projection|,transport|sperm axoneme assembly|protein localization|negative regulation of gene expression|artery smooth muscle contraction|protein transport|striatum development|hippocampus development|cerebral cortex development|cell projection organization|adult behavior|leptin-mediated signaling pathway|protein localization to organelle|negative regulation of appetite by leptin-mediated signaling pathway|negative regulation of multicellular organism growth|positive regulation of multicellular organism growth|vasodilation|cilium assembly|Golgi to plasma membrane protein transport|response to leptin|photoreceptor cell maintenance|brain morphogenesis|cartilage development|cilium morphogenesis|regulation of cilium beat frequency involved in ciliary motility|,RNA polymerase II repressing transcription factor binding|,10,0.1,0.146,10,-0.3,1.03,0,0,0,0.756,0,0,-1.8,1.1
ENSMUSG00000026452,SYT2,synaptotagmin II,cytoplasm|plasma membrane|synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|intracellular membrane-bounded organelle|synapse|,transport|,transporter activity|calcium ion binding|protein binding|calcium-dependent phospholipid binding|calcium-dependent phospholipid binding|syntaxin binding|metal ion binding|,10,0,0,10,0.2,0.623,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000091931,AK010878,cDNA sequence AK010878,None,None,None,1,-0.1,0.00678,1,0,0,0,0,0,0.756,0,0,-2,1.8
ENSMUSG00000058297,SPOCK2,"sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2",extracellular region|proteinaceous extracellular matrix|,signal transduction|positive regulation of cell-substrate adhesion|peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|extracellular matrix organization|,calcium ion binding|calcium ion binding|glycosaminoglycan binding|extracellular matrix binding|,10,0.5,0.405,10,0,0,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000037552,PLEKHG2,"pleckstrin homology domain containing, family G (with RhoGef domain) member 2",None,regulation of Rho protein signal transduction|,guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0,0,10,0.3,0.348,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000022179,4931414P19RIK,RIKEN cDNA 4931414P19 gene,cellular_component|extracellular region|,biological_process|,poly(A) RNA binding|,9,-0.1,0.204,10,0.2,0.132,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000052217,HBB-BH1,"hemoglobin Z, beta-like embryonic chain",hemoglobin complex|blood microparticle|,negative regulation of transcription from RNA polymerase II promoter|transport|oxygen transport|protein heterooligomerization|,oxygen transporter activity|iron ion binding|oxygen binding|heme binding|hemoglobin alpha binding|metal ion binding|,10,-0.9,0.939,10,0.4,1.12,0,0,0,0.756,0,0,-1.9,1.2
ENSMUSG00000042462,DCTPP1,dCTP pyrophosphatase 1,cytoplasm|cytosol|,nucleoside triphosphate catabolic process|protein homotetramerization|,nucleotide binding|magnesium ion binding|pyrophosphatase activity|hydrolase activity|pyrimidine deoxyribonucleotide binding|metal ion binding|nucleoside-triphosphate diphosphatase activity|dCTP diphosphatase activity|,10,0.1,0.357,10,-0.2,0.777,0,0,0,0.756,0,0,-1.5,1.4
ENSMUSG00000047228,BC048546,cDNA sequence BC048546,cellular_component|extracellular region|extracellular space|,negative regulation of peptidase activity|,endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0.1,0.0846,0,0,0,0.756,0,0,-1.6,1.3
ENSMUSG00000005089,SLC1A2,"solute carrier family 1 (glial high affinity glutamate transporter), member 2",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|axolemma|presynaptic membrane|neuron projection|dendritic spine|dendritic shaft|synapse|,transport|dicarboxylic acid transport|nervous system development|visual behavior|response to light stimulus|response to wounding|multicellular organismal aging|L-glutamate transport|L-glutamate transport|L-glutamate transport|telencephalon development|adult behavior|cellular response to extracellular stimulus|multicellular organism growth|sodium ion transmembrane transport|response to drug|response to amino acid|positive regulation of glucose import|L-glutamate import|D-aspartate import|L-alpha-amino acid transmembrane transport|,L-glutamate transmembrane transporter activity|L-glutamate transmembrane transporter activity|high-affinity glutamate transmembrane transporter activity|symporter activity|glutamate:sodium symporter activity|sodium:dicarboxylate symporter activity|,10,-0.2,0.827,10,0,0,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000017004,SVS5,seminal vesicle secretory protein 5,extracellular region|,None,None,9,-0.1,0.108,9,0.1,0.0921,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000022177,HAUS4,"HAUS augmin-like complex, subunit 4",cytoplasm|centrosome|cytoskeleton|microtubule|HAUS complex|,cell cycle|mitotic nuclear division|spindle assembly|centrosome organization|cell division|,molecular_function|,10,-0.1,0.12,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000026018,ICA1L,islet cell autoantigen 1-like,cellular_component|,biological_process|,molecular_function|protein domain specific binding|,10,-0.1,0.00171,10,0.1,0.166,0,0,0,0.756,0,0,-1.9,1.3
ENSMUSG00000013646,SH3BP5L,SH3 binding domain protein 5 like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.00181,0,0,0,0.756,0,0,-1.1,1.8
ENSMUSG00000044526,ZNRF4,zinc and ring finger 4,cytoplasm|,biological_process|,molecular_function|metal ion binding|,9,0,0,9,0,0,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000037339,FAM53A,"family with sequence similarity 53, member A",nucleus|,protein import into nucleus|,molecular_function|,9,0,0,9,0,0,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000056673,KDM5D,lysine (K)-specific demethylase 5D,intracellular|nucleus|,chromatin modification|histone H3-K4 demethylation|oxidation-reduction process|,"sulfonate dioxygenase activity|DNA binding|zinc ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|histone demethylase activity (H3-K4 specific)|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.3,0.477,10,0,0,0,0,0,0.756,0,0,-0.9,1.9
ENSMUSG00000014198,ZFP385C,zinc finger protein 385C,nucleus|,biological_process|,nucleic acid binding|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000038695,JOSD2,Josephin domain containing 2,cellular_component|cytoplasm|,proteolysis|protein deubiquitination|,ubiquitin-specific protease activity|peptidase activity|omega peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000039264,GIMAP3,"GTPase, IMAP family member 3",mitochondrion|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,mitochondrial DNA inheritance|,nucleotide binding|GTP binding|,10,0.1,0.223,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000045110,RASSF8,Ras association (RalGDS/AF-6) domain family (N-terminal) member 8,None,signal transduction|,None,10,0,0,10,0.2,0.211,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000034212,ANKMY1,ankyrin repeat and MYND domain containing 1,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.0922,10,0.1,0.0702,0,0,0,0.756,0,0,-1.9,1.2
ENSMUSG00000048478,SPATA33,spermatogenesis associated 33,cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,9,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000079177,FAM228A,"family with sequence similarity 228, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.7,1.3
ENSMUSG00000037972,SNN,stannin,cellular_component|mitochondrion|mitochondrial outer membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.1,0.277,9,0,0,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000027322,SIGLEC1,"sialic acid binding Ig-like lectin 1, sialoadhesin",extracellular region|plasma membrane|membrane|integral component of membrane|,endocytosis|cell adhesion|positive regulation of T cell apoptotic process|positive regulation of extrinsic apoptotic signaling pathway|,protein binding|,10,-0.3,0.981,10,0.2,0.407,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000072571,TMEM253,transmembrane protein 253,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.2,0.209,9,0,0,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000060798,INTU,inturned planar cell polarity effector homolog (Drosophila),cytoplasm|,multicellular organismal development|nervous system development|regulation of smoothened signaling pathway|negative regulation of keratinocyte proliferation|spinal cord dorsal/ventral patterning|cell projection organization|keratinocyte differentiation|hair follicle morphogenesis|cilium assembly|positive regulation of smoothened signaling pathway|negative regulation of cell division|limb development|cilium morphogenesis|,molecular_function|,10,0,0,10,0.2,0.42,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000020776,FBF1,Fas (TNFRSF6) binding factor 1,spindle pole|cytoplasm|centriole|centriole|cytoskeleton|cell junction|apical junction complex|keratin filament|ciliary transition fiber|,cell projection organization|cilium assembly|apical junction assembly|establishment of epithelial cell polarity|,protein binding|,10,-0.1,0.0708,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000007021,SYNGR3,synaptogyrin 3,synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|neuromuscular junction|synapse|,positive regulation of transporter activity|,protein binding|SH2 domain binding|protein N-terminus binding|,9,0.1,0.115,9,-0.2,0.269,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000020878,LRRC46,leucine rich repeat containing 46,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0521,10,-0.4,0.000573,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000094651,GAL3ST2,galactose-3-O-sulfotransferase 2,membrane|,glycoprotein biosynthetic process|sulfation|,sulfotransferase activity|galactose 3-O-sulfotransferase activity|,10,0,0,10,0.4,1.8,0,0,0,0.756,0,0,-0.9,2
ENSMUSG00000046814,GCHFR,GTP cyclohydrolase I feedback regulator,nucleus|cytoplasm|membrane|dendrite|nuclear membrane|melanosome|protein complex|,protein complex assembly|negative regulation of biosynthetic process|negative regulation of GTP cyclohydrolase I activity|protein heterooligomerization|,enzyme inhibitor activity|amino acid binding|hydrolase activity|enzyme binding|GTP-dependent protein binding|GTP cyclohydrolase binding|,10,0.2,0.653,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000020297,NSG2,neuron specific gene family member 2,endosome|Golgi apparatus|membrane|integral component of membrane|cytoplasmic vesicle|,dopamine receptor signaling pathway|clathrin coat assembly|,clathrin light chain binding|,10,0,0,10,-0.1,0.238,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000059482,2610301B20RIK,RIKEN cDNA 2610301B20 gene,cytoplasm|plasma membrane|cell junction|,biological_process|,molecular_function|,9,0.1,0.224,9,0,0,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000026017,CARF,calcium response factor,nucleus|nucleus|nucleoplasm|nucleolus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular response to potassium ion|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter in response to calcium ion|cellular response to calcium ion|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1,2
ENSMUSG00000034334,FAM151B,"family with sequence similarity 151, member B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000060429,SNTB1,"syntrophin, basic 1",cytoplasm|cytoskeleton|plasma membrane|membrane|cell junction|protein complex|synapse|,None,actin binding|protein binding|calmodulin binding|PDZ domain binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000034911,USHBP1,Usher syndrome 1C binding protein 1,cellular_component|,biological_process|,PDZ domain binding|,10,-0.1,0.146,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000063320,1190007I07RIK,RIKEN cDNA 1190007I07 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.9,0.0893,10,0,0,0,0,0,0.756,0,0,-2,0.9
ENSMUSG00000031820,BABAM1,BRISC and BRCA1 A complex member 1,nucleus|cytoplasm|BRCA1-A complex|BRISC complex|,DNA repair|double-strand break repair|cellular response to DNA damage stimulus|response to ionizing radiation|chromatin modification|G2 DNA damage checkpoint|positive regulation of DNA repair|protein K63-linked deubiquitination|,molecular_function|,10,-0.1,0.199,10,0,0,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000022487,GTSF1,gametocyte specific factor 1,cytoplasm|,None,metal ion binding|,10,0.3,0.123,10,0,0,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000038022,FAM188B,"family with sequence similarity 188, member B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.8,1.3
ENSMUSG00000040606,KAZN,"kazrin, periplakin interacting protein",cornified envelope|nucleus|cytoplasm|cytoskeleton|cell junction|desmosome|,keratinization|,None,10,0,0,9,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000026796,FAM129B,"family with sequence similarity 129, member B",cytoplasm|cytosol|cytosol|plasma membrane|adherens junction|actin cytoskeleton|cell junction|extracellular vesicular exosome|,negative regulation of apoptotic process|,None,10,0,0,10,0.2,0.41,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000044034,NPB,neuropeptide B,extracellular region|extracellular space|,G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,G-protein coupled receptor binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000016984,ETAA1,Ewing tumor-associated antigen 1,cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0.2,0.509,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000021404,SERPINB9C,"serine (or cysteine) peptidase inhibitor, clade B, member 9c",cytoplasm|,negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000044468,FAM46C,"family with sequence similarity 46, member C",cellular_component|,biological_process|,molecular_function|,10,0.1,0.102,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000039813,TBC1D2,"TBC1 domain family, member 2",cytoplasm|cell junction|cytoplasmic vesicle|,regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|,GTPase activator activity|Rab GTPase activator activity|cadherin binding|,10,0.1,0.0231,10,1.3,0.862,0,0,0,0.756,0,0,-0.7,2
ENSMUSG00000070476,FAM217B,"family with sequence similarity 217, member B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.076,0,0,0,0.756,0,0,-1.6,1.3
ENSMUSG00000047369,DNAH14,"dynein, axonemal, heavy chain 14",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.193,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000090266,METTL23,methyltransferase like 23,cellular_component|cytoplasm|membrane|integral component of membrane|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,-0.1,0.153,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000079470,UTP14B,"UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast)",nucleus|virion|viral nucleocapsid|ribonucleoprotein complex|small-subunit processome|,rRNA processing|meiotic nuclear division|multicellular organismal development|spermatogenesis|cell differentiation|ribosome biogenesis|,None,10,-0.1,0.0336,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000021815,MSS51,MSS51 mitochondrial translational activator,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000024503,SPINK3,"serine peptidase inhibitor, Kazal type 3",extracellular region|extracellular space|,negative regulation of peptidase activity|negative regulation of nitric oxide mediated signal transduction|negative regulation of peptidyl-tyrosine phosphorylation|regulation of acrosome reaction|negative regulation of calcium ion import|negative regulation of serine-type endopeptidase activity|negative regulation of serine-type endopeptidase activity|regulation of store-operated calcium entry|,serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.1,0.133,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000090777,GM7873,predicted gene 7873,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000019461,PLSCR3,phospholipid scramblase 3,mitochondrion|plasma membrane|membrane|integral component of membrane|,apoptotic process|glucose homeostasis|cholesterol homeostasis|,SH3 domain binding|calcium-dependent protein binding|,10,0,0,10,0.3,1.28,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000006576,SLC4A3,"solute carrier family 4 (anion exchanger), member 3",plasma membrane|membrane|integral component of membrane|,transport|ion transport|anion transport|ion transmembrane transport|regulation of intracellular pH|,transporter activity|inorganic anion exchanger activity|anion transmembrane transporter activity|antiporter activity|anion:anion antiporter activity|,10,0,0,10,0.1,0.173,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000041117,CCDC8,coiled-coil domain containing 8,cytoplasm|centrosome|plasma membrane|3M complex|,microtubule cytoskeleton organization|regulation of mitosis|negative regulation of phosphatase activity|,molecular_function|,9,0.1,0.0674,9,0,0,0,0,0,0.756,0,0,-1,2
ENSMUSG00000062590,ARMC9,armadillo repeat containing 9,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0644,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000059554,CCDC28A,coiled-coil domain containing 28A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000035878,HYKK,hydroxylysine kinase 1,cellular_component|cytoplasm|,biological_process|phosphorylation|,"molecular_function|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|hydroxylysine kinase activity|",10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000028214,GEM,GTP binding protein (gene overexpressed in skeletal muscle),nucleus|plasma membrane|cytoplasmic side of plasma membrane|membrane|midbody|spindle midzone|mitotic spindle|,GTP catabolic process|mitotic nuclear division|signal transduction|small GTPase mediated signal transduction|chromosome organization|metaphase plate congression|,nucleotide binding|magnesium ion binding|GTPase activity|protein binding|GTP binding|GDP binding|,10,0,0,10,0.2,0.294,0,0,0,0.756,0,0,-1,2
ENSMUSG00000021782,DLG5,"discs, large homolog 5 (Drosophila)",cell-cell adherens junction|,protein complex assembly|polarized epithelial cell differentiation|midbrain development|apical protein localization|zonula adherens assembly|establishment or maintenance of epithelial cell apical/basal polarity|epithelial tube branching involved in lung morphogenesis|protein localization to adherens junction|metanephric collecting duct development|,protein binding|beta-catenin binding|cytoskeletal protein binding|,10,0.1,0.156,10,0,0,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000042202,SLC35E2,"solute carrier family 35, member E2",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000026831,1700007K13RIK,RIKEN cDNA 1700007K13 gene,cellular_component|,biological_process|,molecular_function|,10,0.6,0.678,10,0,0,0,0,0,0.756,0,0,-0.8,2
ENSMUSG00000014243,ZSWIM7,zinc finger SWIM-type containing 7,nucleus|Shu complex|,double-strand break repair via homologous recombination|DNA repair|DNA recombination|cellular response to DNA damage stimulus|protein stabilization|,molecular_function|zinc ion binding|metal ion binding|,10,0,0,10,0.2,0.191,0,0,0,0.756,0,0,-1,2
ENSMUSG00000045349,SH2D5,SH2 domain containing 5,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000020328,NUDCD2,NudC domain containing 2,"chromosome, centromeric region|kinetochore|intracellular|chromosome|cytoplasm|cytoskeleton|microtubule cytoskeleton|extracellular vesicular exosome|",biological_process|,molecular_function|,10,0,0,10,-0.3,0.214,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000044976,WDR72,WD repeat domain 72,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000036411,9530077C05RIK,RIKEN cDNA 9530077C05 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000071722,SPIN4,"spindlin family, member 4",cellular_component|,gamete generation|biological_process|,molecular_function|,9,0.2,0.516,9,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000052631,SH2D6,SH2 domain containing 6,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.604,0,0,0,0.756,0,0,-0.8,2
ENSMUSG00000038570,FAM154B,"family with sequence similarity 154, member B",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.135,10,0.2,0.875,0,0,0,0.756,0,0,-0.9,2
ENSMUSG00000046618,OLFML2A,olfactomedin-like 2A,extracellular region|extracellular matrix|,extracellular matrix organization|,protein homodimerization activity|extracellular matrix binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000037410,TBC1D2B,"TBC1 domain family, member 2B",cellular_component|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,0,0,10,-0.2,0.303,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000050944,EFCAB5,EF-hand calcium binding domain 5,cellular_component|,biological_process|,molecular_function|calcium ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000056222,SPOCK1,"sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1",extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|sarcoplasm|neuromuscular junction|node of Ranvier|,signal transduction|negative regulation of cell-substrate adhesion|negative regulation of endopeptidase activity|negative regulation of neuron projection development|,cysteine-type endopeptidase inhibitor activity|calcium ion binding|metalloendopeptidase inhibitor activity|,10,0,0,10,0.4,1.37,0,0,0,0.756,0,0,-0.8,2
ENSMUSG00000025185,LOXL4,lysyl oxidase-like 4,extracellular region|extracellular region|membrane|receptor complex|extracellular vesicular exosome|,oxidation-reduction process|,"protein-lysine 6-oxidase activity|scavenger receptor activity|copper ion binding|aspartate oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor|D-lysine oxidase activity|metal ion binding|",10,0,0,10,-1.1,0.178,0,0,0,0.756,0,0,-2,1.1
ENSMUSG00000026932,NACC2,"nucleus accumbens associated 2, BEN and BTB (POZ) domain containing",nuclear chromatin|nucleus|NuRD complex|,"transcription from RNA polymerase II promoter|negative regulation of cell proliferation|posttranscriptional regulation of gene expression|histone deacetylation|cellular protein complex localization|negative regulation of transcription, DNA-templated|protein homooligomerization|negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter|positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II transcription factor binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|histone deacetylase activity|protein homodimerization activity|histone deacetylase binding|,10,0,0,10,-0.3,0.498,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000072754,LRCOL1,leucine rich colipase-like 1,cellular_component|extracellular region|,digestion|biological_process|lipid catabolic process|,molecular_function|enzyme activator activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1,2
ENSMUSG00000006527,SFMBT1,Scm-like with four mbt domains 1,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|chromatin modification|cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of muscle organ development|",histone binding|,10,0,0,10,-0.2,0.477,0,0,0,0.756,0,0,-1.7,1.2
ENSMUSG00000045319,PROSER2,proline and serine rich 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.322,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000023968,CRIP3,cysteine-rich protein 3,cytoplasm|,T cell proliferation|,molecular_function|zinc ion binding|metal ion binding|,9,0,0,9,0.1,0.0319,0,0,0,0.756,0,0,-0.9,2
ENSMUSG00000044433,CAMSAP3,"calmodulin regulated spectrin-associated protein family, member 3",cytoplasm|centrosome|cytoskeleton|microtubule|zonula adherens|cell junction|microtubule minus-end|,microtubule cytoskeleton organization|negative regulation of phosphatase activity|regulation of organelle organization|regulation of organelle organization|microtubule anchoring|zonula adherens maintenance|regulation of microtubule cytoskeleton organization|epithelial cell-cell adhesion|,protein binding|microtubule binding|microtubule minus-end binding|,10,0,0,10,-0.3,0.463,0,0,0,0.756,0,0,-1.7,1.6
ENSMUSG00000034105,TLDC1,TBC/LysM associated domain containing 1,lysosomal membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000032332,COL12A1,"collagen, type XII, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type XII trimer|extracellular space|extracellular matrix|extracellular vesicular exosome|,cell adhesion|,None,10,-1,1.21,10,0,0,0,0,0,0.756,0,0,-2,0.8
ENSMUSG00000073600,PROB1,proline rich basic protein 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.00725,10,0,0,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000014075,TCTEX1D2,Tctex1 domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0392,10,0,0,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000034059,YPEL4,yippee-like 4 (Drosophila),cellular_component|nucleus|,biological_process|,molecular_function|,10,0,0,10,0.1,0.186,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000031513,LEPROTL1,leptin receptor overlapping transcript-like 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.1,0.244,9,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000048495,TYW5,tRNA-yW synthesizing protein 5,cellular_component|,tRNA processing|wybutosine biosynthetic process|oxidation-reduction process|,"tRNA binding|iron ion binding|oxidoreductase activity|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|protein homodimerization activity|metal ion binding|dioxygenase activity|",10,0.1,0.0516,10,-0.3,0.777,0,0,0,0.756,0,0,-1.7,1.1
ENSMUSG00000047150,1700001C19RIK,RIKEN cDNA 1700001C19 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.383,10,0.1,0.0625,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000047613,A430005L14RIK,RIKEN cDNA A430005L14 gene,nucleus|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000041609,CCDC64,coiled-coil domain containing 64,intracellular|cell|cytoplasm|centrosome|cytoskeleton|,transport|nervous system development|neuron projection development|Golgi to secretory granule transport|,protein binding|Rab GTPase binding|dynactin binding|,10,0,0,10,0.1,0.013,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000041263,RUSC1,RUN and SH3 domain containing 1,nucleus|cytoplasm|endosome|early endosome|Golgi apparatus|cytoskeleton|microtubule|plasma membrane|microtubule cytoskeleton|membrane|cell junction|cytoplasmic vesicle|synapse|postsynaptic membrane|,protein polyubiquitination|,actin binding|,10,-0.1,0.00362,10,0.1,0.314,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000038593,TCTN1,tectonic family member 1,extracellular region|extracellular space|cytoplasm|cytoskeleton|membrane|ciliary transition zone|TCTN-B9D complex|cell projection|,in utero embryonic development|neural tube formation|multicellular organismal development|regulation of smoothened signaling pathway|somatic motor neuron differentiation|telencephalon development|dorsal/ventral neural tube patterning|central nervous system interneuron axonogenesis|cell projection organization|cilium morphogenesis|,protein binding|,10,0,0,10,-0.1,0.0216,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000036087,SLAIN2,"SLAIN motif family, member 2",nucleus|cytoplasm|centrosome|cytoskeleton|microtubule cytoskeleton|microtubule plus-end|,microtubule nucleation|regulation of microtubule polymerization|positive regulation of microtubule polymerization|cytoplasmic microtubule organization|cytoplasmic microtubule organization|,molecular_function|,10,0,0,10,-0.3,0.686,0,0,0,0.756,0,0,-2,0.9
ENSMUSG00000068859,SP9,trans-acting transcription factor 9,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|embryonic limb morphogenesis|",nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.6
ENSMUSG00000003824,SYCE2,synaptonemal complex central element protein 2,synaptonemal complex|central element|nucleus|chromosome|,cell cycle|meiotic nuclear division|synaptonemal complex assembly|cell division|,protein binding|,10,1.2,0.79,10,0.1,0.0618,0,0,0,0.756,0,0,-0.8,2
ENSMUSG00000076433,BC100451,cDNA sequence BC100451,cilium|motile cilium|cell projection|,biological_process|,protein binding|,10,0,0,10,0.1,0.0405,0,0,0,0.756,0,0,-1.1,1.8
ENSMUSG00000027650,TTI1,TELO2 interacting protein 1,cytoplasm|TORC1 complex|TORC2 complex|,regulation of TOR signaling|,molecular_function|,10,-0.2,0.565,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000025383,IL23A,"interleukin 23, alpha subunit p19",extracellular region|extracellular space|interleukin-23 complex|,positive regulation of T cell mediated cytotoxicity|positive regulation of defense response to virus by host|positive regulation of defense response to virus by host|immune system process|positive regulation of T-helper 1 type immune response|positive regulation of T-helper 1 type immune response|inflammatory response|immune response|positive regulation of activation of JAK2 kinase activity|negative regulation of interleukin-10 production|positive regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of interferon-gamma production|positive regulation of interleukin-10 production|positive regulation of interleukin-12 production|positive regulation of interleukin-17 production|positive regulation of tumor necrosis factor production|positive regulation of natural killer cell proliferation|T cell proliferation|positive regulation of T cell proliferation|positive regulation of activated T cell proliferation|regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat4 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of memory T cell differentiation|innate immune response|positive regulation of osteoclast differentiation|positive regulation of transcription from RNA polymerase II promoter|tissue remodeling|defense response to Gram-negative bacterium|positive regulation of NK T cell activation|positive regulation of NK T cell proliferation|defense response to virus|positive regulation of neutrophil chemotaxis|positive regulation of T-helper 17 type immune response|positive regulation of T-helper 17 cell lineage commitment|,cytokine activity|protein binding|interleukin-23 receptor binding|interleukin-23 receptor binding|,10,0.2,0.0708,10,0,0,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000048707,TPRN,taperin,stereocilium|cell projection|,sensory perception of sound|,molecular_function|phosphatase binding|,10,0,0,10,-0.2,0.719,0,0,0,0.756,0,0,-1,1.9
ENSMUSG00000055013,AGAP1,"ArfGAP with GTPase domain, ankyrin repeat and PH domain 1",intracellular|cytoplasm|cytosol|,GTP catabolic process|transport|small GTPase mediated signal transduction|protein transport|regulation of ARF GTPase activity|,nucleotide binding|GTPase activity|GTPase activator activity|GTP binding|phospholipid binding|ARF GTPase activator activity|zinc ion binding|metal ion binding|,9,-1,0.141,9,0,0,0,0,0,0.756,0,0,-1.9,1.5
ENSMUSG00000091721,GM5549,predicted gene 5549,cellular_component|,biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000048455,SPRR1B,small proline-rich protein 1B,cornified envelope|cytoplasm|,regulation of cell shape|peptide cross-linking|keratinization|,structural constituent of cytoskeleton|,10,0.2,0.0715,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000023009,NCKAP5L,NCK-associated protein 5-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000045257,MORN2,MORN repeat containing 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000036863,SYDE2,"synapse defective 1, Rho GTPase, homolog 2 (C. elegans)",cellular_component|,biological_process|,molecular_function|,9,-0.1,0.0679,9,0.2,0.256,0,0,0,0.756,0,0,-1.2,1.9
ENSMUSG00000001918,SLC1A5,"solute carrier family 1 (neutral amino acid transporter), member 5",Golgi apparatus|plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,amino acid transmembrane transport|amino acid transmembrane transport|transport|dicarboxylic acid transport|extracellular amino acid transport|neutral amino acid transport|L-serine transport|L-alpha-amino acid transmembrane transport|,amino acid transmembrane transporter activity|neutral amino acid transmembrane transporter activity|L-serine transmembrane transporter activity|symporter activity|sodium:dicarboxylate symporter activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.7
ENSMUSG00000073063,HBQ1B,"hemoglobin, theta 1B",cellular_component|,transport|biological_process|oxygen transport|,molecular_function|oxygen transporter activity|metal ion binding|,6,0,0,6,-0.1,0.06,0,0,0,0.756,0,0,-1.8,1.5
ENSMUSG00000058690,CCSER2,coiled-coil serine rich 2,microtubule cytoskeleton|,microtubule bundle formation|,microtubule binding|,9,0,0,10,-0.6,0.66,0,0,0,0.756,0,0,-1.8,1.3
ENSMUSG00000061065,GM5382,predicted gene 5382,nucleosome|cellular_component|nucleus|chromosome|,biological_process|,molecular_function|DNA binding|,9,0,0,9,0.2,0.481,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000042363,LGALSL,"lectin, galactoside binding-like",intracellular|,biological_process|,molecular_function|carbohydrate binding|,10,0,0,10,-0.1,0.341,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000038781,STAP2,signal transducing adaptor family member 2,cytoplasm|plasma membrane|membrane|,None,protein binding|,10,0,0,10,-0.2,1.05,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000068882,SSB,Sjogren syndrome antigen B,nucleus|ribonucleoprotein complex|,RNA processing|tRNA processing|,nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,0,0,10,0.3,0.147,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000020303,STC2,stanniocalcin 2,extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|,cellular calcium ion homeostasis|cellular calcium ion homeostasis|response to oxidative stress|endoplasmic reticulum unfolded protein response|response to endoplasmic reticulum stress|negative regulation of multicellular organism growth|calcium ion homeostasis|regulation of sodium-dependent phosphate transport|regulation of store-operated calcium entry|,hormone activity|protein binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000021747,4930452B06RIK,RIKEN cDNA 4930452B06 gene,cellular_component|,biological_process|,molecular_function|,9,0,0,10,0.1,0.00598,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000026611,SPATA17,spermatogenesis associated 17,cellular_component|cytoplasm|,biological_process|,molecular_function|calmodulin binding|,10,0.1,0.117,10,0,0,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000001948,SPA17,sperm autoantigenic protein 17,cytoplasm|membrane|motile cilium|primary cilium|,binding of sperm to zona pellucida|,None,10,0,0,10,0.4,1.82,0,0,0,0.756,0,0,-0.8,2
ENSMUSG00000036002,FAM214B,"family with sequence similarity 214, member B",nucleus|,biological_process|,molecular_function|,10,0,0,10,0.3,0.0962,0,0,0,0.756,0,0,-1,1.9
ENSMUSG00000026956,UAP1L1,UDP-N-acteylglucosamine pyrophosphorylase 1-like 1,cellular_component|,biological_process|metabolic process|,"molecular_function|telomerase activity|RNA helicase activity|DNA primase activity|sulfate adenylyltransferase activity|RNA guanylyltransferase activity|tRNA guanylyltransferase activity|mannose-phosphate guanylyltransferase activity|transferase activity|nucleotidyltransferase activity|DNA/RNA helicase activity|CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity|phospholactate guanylyltransferase activity|ATP:coenzyme F420 adenylyltransferase activity|UDP-N-acetylgalactosamine diphosphorylase activity|uridylyltransferase activity|",9,0,0,9,0,0,0,0,0,0.756,0,0,-1.5,1.7
ENSMUSG00000046694,FAM46B,"family with sequence similarity 46, member B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000001103,SEBOX,SEBOX homeobox,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|embryo development ending in birth or egg hatching|cell differentiation|oogenesis|",molecular_function|DNA binding|,10,0.6,1.5,10,-0.2,0.957,0,0,0,0.756,0,0,-0.9,1.9
ENSMUSG00000052794,1700030K09RIK,RIKEN cDNA 1700030K09 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.298,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000066842,HMCN1,hemicentin 1,extracellular region|basement membrane|cell cortex|cell junction|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0577,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000039738,SLX4,SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae),"nuclear chromosome, telomeric region|nuclear chromatin|nucleus|cytoplasm|cell junction|Slx1-Slx4 complex|Holliday junction resolvase complex|ERCC4-ERCC1 complex|","double-strand break repair via homologous recombination|DNA catabolic process, endonucleolytic|DNA replication|DNA repair|nucleotide-excision repair|DNA recombination|cellular response to DNA damage stimulus|DNA double-strand break processing involved in repair via single-strand annealing|positive regulation of catalytic activity|response to intra-S DNA damage checkpoint signaling|",enzyme activator activity|crossover junction endodeoxyribonuclease activity|5'-flap endonuclease activity|3'-flap endonuclease activity|,10,0.2,0.465,10,0,0,0,0,0,0.756,0,0,-1.1,1.8
ENSMUSG00000035829,PPP1R26,"protein phosphatase 1, regulatory subunit 26",nucleus|,negative regulation of phosphatase activity|,protein phosphatase inhibitor activity|phosphatase binding|,10,0,0,10,0.2,0.44,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000018986,SLFN3,schlafen 3,None,negative regulation of cell proliferation|,None,10,-0.4,0.605,10,0,0,0,0,0,0.756,0,0,-1.8,1.1
ENSMUSG00000009894,SNAP47,"synaptosomal-associated protein, 47",cytoplasm|membrane|dendrite|BLOC-1 complex|neuronal cell body|,long-term synaptic potentiation|,molecular_function|,10,-0.1,0.197,10,0.2,0.26,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000052688,5430435G22RIK,RIKEN cDNA 5430435G22 gene,lysosome|lysosome|endosome|late endosome|late endosome|Golgi apparatus|trans-Golgi network|membrane|cytoplasmic vesicle|phagocytic vesicle|,transport|small GTPase mediated signal transduction|protein transport|positive regulation of interleukin-6 production|negative regulation of toll-like receptor 4 signaling pathway|negative regulation of toll-like receptor 9 signaling pathway|late endosome to Golgi transport|positive regulation of megakaryocyte differentiation|positive regulation of NF-kappaB transcription factor activity|,nucleotide binding|GTP binding|,10,0.1,0.147,10,-0.2,0.104,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000022864,D16ERTD472E,"DNA segment, Chr 16, ERATO Doi 472, expressed",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0482,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000040380,CBLN3,cerebellin 3 precursor protein,extracellular region|extracellular space|extracellular space|endoplasmic reticulum|Golgi apparatus|cell junction|synapse|,biological_process|,protein binding|,10,0,0,10,-0.2,0.182,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000000693,LOXL3,lysyl oxidase-like 3,extracellular region|membrane|,"epithelial to mesenchymal transition|negative regulation of transcription, DNA-templated|oxidation-reduction process|","scavenger receptor activity|copper ion binding|aspartate oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor|D-lysine oxidase activity|metal ion binding|",10,0,0,10,0.3,1.29,0,0,0,0.756,0,0,-1.1,1.7
ENSMUSG00000042155,KLHL23,kelch-like 23,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0713,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000028843,SH3BGRL3,SH3 domain binding glutamic acid-rich protein-like 3,nucleus|cytoplasm|lamellipodium|extracellular vesicular exosome|,regulation of actin filament depolymerization|positive regulation of Rho GTPase activity|regulation of actin cytoskeleton organization|regulation of blood vessel endothelial cell migration|cell redox homeostasis|,Rho GTPase activator activity|electron carrier activity|protein disulfide oxidoreductase activity|semaphorin receptor binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.8,1.3
ENSMUSG00000051517,ARHGEF39,Rho guanine nucleotide exchange factor (GEF) 39,plasma membrane|membrane|,positive regulation of cell migration|regulation of Rho protein signal transduction|,molecular_function|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000037962,FAM101A,"family with sequence similarity 101, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,0.847,0,0,0,0.756,0,0,-1.1,1.8
ENSMUSG00000047180,NEURL3,neuralized homolog 3 homolog (Drosophila),cellular_component|,protein ubiquitination|,"ubiquitin-protein transferase activity|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.1,0.0138,10,-0.1,0.000973,0,0,0,0.756,0,0,-1.2,1.7
ENSMUSG00000046999,1110032F04RIK,RIKEN cDNA 1110032F04 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.275,10,0.1,0.264,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000047844,BEX4,brain expressed gene 4,nucleus|cytoplasm|,biological_process|,molecular_function|,10,-0.2,0.164,10,0,0,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000031671,SETD6,SET domain containing 6,nucleus|cytoplasm|,peptidyl-lysine monomethylation|negative regulation of NF-kappaB transcription factor activity|methylation|regulation of inflammatory response|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|NF-kappaB binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",9,-0.2,0.666,9,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000014837,4931428F04RIK,RIKEN cDNA 4931428F04 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000041481,SERPINA3G,"serine (or cysteine) peptidase inhibitor, clade A, member 3G",extracellular region|extracellular space|nucleus|cytoplasm|,immune system process|apoptotic process|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,serine-type endopeptidase inhibitor activity|cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000036022,FAM122B,"family with sequence similarity 122, member B",cellular_component|collagen trimer|,biological_process|,molecular_function|,10,0,0,10,0.5,0.588,0,0,0,0.756,0,0,-1,1.8
ENSMUSG00000030590,FAM98C,"family with sequence similarity 98, member C",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000031105,SLC25A14,"solute carrier family 25 (mitochondrial carrier, brain), member 14",mitochondrion|mitochondrial envelope|mitochondrial inner membrane|membrane|integral component of membrane|mitochondrial membrane|,transport|mitochondrial transport|,None,10,-0.8,0.209,10,0,0,0,0,0,0.756,0,0,-2,1
ENSMUSG00000059562,CCDC154,coiled-coil domain containing 154,cellular_component|endosome|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.237,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000053153,SPAG16,sperm associated antigen 16,nucleus|cytoplasm|cytoskeleton|cilium|axoneme|microtubule cytoskeleton|cell projection|,spermatogenesis|cell projection organization|cilium assembly|,protein binding|protein kinase binding|,10,0,0,10,0.1,0.00119,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000030555,TTC23,tetratricopeptide repeat domain 23,cellular_component|,biological_process|,molecular_function|,10,0.6,0.352,10,0,0,0,0,0,0.756,0,0,-0.9,2
ENSMUSG00000071659,HNRNPUL2,heterogeneous nuclear ribonucleoprotein U-like 2,nucleus|membrane|,biological_process|,nucleic acid binding|protein binding|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000047990,C2CD4A,C2 calcium-dependent domain containing 4A,cellular_component|,biological_process|,molecular_function|,9,-0.2,0.274,10,0.2,0.584,0,0,0,0.756,0,0,-1.5,1.5
ENSMUSG00000068686,CD59B,CD59b antigen,extracellular region|extracellular space|plasma membrane|plasma membrane|cell surface|cell surface|membrane|anchored component of membrane|anchored component of external side of plasma membrane|sarcolemma|compact myelin|extracellular vesicular exosome|,cell activation|negative regulation of activation of membrane attack complex|negative regulation of activation of membrane attack complex|cell surface receptor signaling pathway|positive regulation of T cell proliferation|negative regulation of apoptotic process|negative regulation of complement activation|negative regulation of cytolysis|,complement binding|complement binding|,10,0,0,10,-0.2,0.429,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000004894,HAPLN2,hyaluronan and proteoglycan link protein 2,extracellular region|proteinaceous extracellular matrix|extracellular matrix|,cell adhesion|establishment of blood-nerve barrier|extracellular matrix assembly|,hyaluronic acid binding|,10,0.2,0.078,10,-0.1,0.0771,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000050471,FAM118B,"family with sequence similarity 118, member B",cellular_component|,biological_process|,molecular_function|,10,0.2,0.121,10,0,0,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000082101,SLFN14,schlafen 14,None,None,None,10,0,0,10,0.1,0.0259,0,0,0,0.756,0,0,-1.9,1.1
ENSMUSG00000027646,SRC,Rous sarcoma oncogene,intracellular|nucleus|cytoplasm|mitochondrion|mitochondrial inner membrane|lysosome|late endosome|cytosol|cytoskeleton|plasma membrane|plasma membrane|caveola|postsynaptic density|membrane|neuron projection|extracellular vesicular exosome|,"immune system process|protein phosphorylation|cell cycle|cell adhesion|cell proliferation|positive regulation of gene expression|positive regulation of glucose metabolic process|positive regulation of smooth muscle cell migration|phosphorylation|cell migration|peptidyl-serine phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|forebrain development|positive regulation of protein autophosphorylation|activation of protein kinase B activity|negative regulation of protein homooligomerization|regulation of intracellular estrogen receptor signaling pathway|adherens junction organization|substrate adhesion-dependent cell spreading|intracellular signal transduction|intracellular signal transduction|osteoclast development|positive regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of protein binding|positive regulation of MAP kinase activity|positive regulation of phosphatidylinositol 3-kinase activity|transcytosis|bone resorption|positive regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of cell adhesion|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of insulin receptor signaling pathway|protein autophosphorylation|neurotrophin TRK receptor signaling pathway|oogenesis|positive regulation of cytokine secretion|progesterone receptor signaling pathway|positive regulation of protein transport|negative regulation of focal adhesion assembly|positive regulation of protein kinase B signaling|negative regulation of mitochondrial depolarization|uterus development|branching involved in mammary gland duct morphogenesis|regulation of cell projection assembly|positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|response to interleukin-1|cellular response to progesterone stimulus|positive regulation of podosome assembly|positive regulation of podosome assembly|positive regulation of canonical Wnt signaling pathway|positive regulation of intracellular signal transduction|positive regulation of DNA biosynthetic process|negative regulation of anoikis|negative regulation of extrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway|","nucleotide binding|protein kinase activity|protein kinase activity|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|protein kinase C binding|receptor binding|insulin receptor binding|protein binding|ATP binding|protein C-terminus binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|enzyme binding|protein kinase binding|protein domain specific binding|heme binding|estrogen receptor binding|protein complex binding|SH2 domain binding|ion channel binding|ephrin receptor binding|ephrin receptor binding|cell adhesion molecule binding|phosphoprotein binding|growth factor receptor binding|",10,0.1,0.0441,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000050883,4930523C07RIK,RIKEN cDNA 4930523C07 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.4,0.227,0,0,0,0.756,0,0,-1.7,1.1
ENSMUSG00000046139,PATL1,protein associated with topoisomerase II homolog 1 (yeast),cytoplasmic mRNA processing body|nucleus|cytoplasm|CCR4-NOT complex|intracellular membrane-bounded organelle|,deadenylation-dependent decapping of nuclear-transcribed mRNA|negative regulation of translation|cytoplasmic mRNA processing body assembly|,G-quadruplex RNA binding|RNA binding|poly(U) RNA binding|translation repressor activity|poly(G) binding|poly(A) RNA binding|,10,-0.1,0.117,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000010136,PIFO,primary cilia formation,nucleus|cytoplasm|Golgi apparatus|trans-Golgi network|cytoplasmic vesicle|ciliary basal body|,cell projection organization|regulation of cell projection organization|positive regulation of kinase activity|,protein binding|Rab GTPase binding|Rab GTPase binding|kinesin binding|kinesin binding|protein kinase binding|protein kinase binding|gamma-tubulin binding|gamma-tubulin binding|beta-tubulin binding|beta-tubulin binding|,10,-0.2,0.0864,10,0,0,0,0,0,0.756,0,0,-1.8,1.1
ENSMUSG00000048905,4930539E08RIK,RIKEN cDNA 4930539E08 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.198,0,0,0,0.756,0,0,-1.2,1.8
ENSMUSG00000029188,SLC34A2,"solute carrier family 34 (sodium phosphate), member 2",brush border|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|brush border membrane|microvillus membrane|,in utero embryonic development|transport|ion transport|sodium ion transport|phosphate ion transport|phosphate ion transport|phosphate ion transport|cellular phosphate ion homeostasis|phosphate ion transmembrane transport|phosphate ion transmembrane transport|sodium ion transmembrane transport|sodium-dependent phosphate transport|,sodium:phosphate symporter activity|symporter activity|sodium-dependent phosphate transmembrane transporter activity|sodium-dependent phosphate transmembrane transporter activity|protein domain specific binding|sodium ion binding|phosphate ion binding|,10,0.1,0.0744,10,-0.1,0.157,0,0,0,0.756,0,0,-1.5,1.4
ENSMUSG00000002804,NUDT14,nudix (nucleoside diphosphate linked moiety X)-type motif 14,cytoplasm|extracellular vesicular exosome|,None,"UDP-sugar diphosphatase activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|metal ion binding|ADP-ribose diphosphatase activity|",10,0.1,0.0926,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000037139,MYOM3,"myomesin family, member 3",cytoplasm|M band|,biological_process|,protein homodimerization activity|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000063632,SOX11,SRY (sex determining region Y)-box 11,nucleus|nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|skeletal system development|neural tube formation|lens morphogenesis in camera-type eye|outflow tract morphogenesis|cardiac ventricle formation|noradrenergic neuron differentiation|noradrenergic neuron differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|translation|multicellular organismal development|nervous system development|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of gene expression|negative regulation of gene expression|negative regulation of gene expression|glial cell proliferation|neural crest cell development|spinal cord development|glial cell development|cell differentiation|positive regulation of BMP signaling pathway|positive regulation of hippo signaling|skeletal muscle cell differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of neuron differentiation|positive regulation of osteoblast differentiation|positive regulation of ossification|positive regulation of ossification|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of hormone secretion|sympathetic nervous system development|embryonic digestive tract morphogenesis|embryonic skeletal system morphogenesis|negative regulation of lymphocyte proliferation|positive regulation of neurogenesis|hard palate development|soft palate development|limb bud formation|negative regulation of glial cell proliferation|negative regulation of glial cell proliferation|ventricular septum morphogenesis|lung morphogenesis|negative regulation of cell death|neuroepithelial cell differentiation|eyelid development in camera-type eye|somite development|cornea development in camera-type eye|closure of optic fissure|positive regulation of stem cell proliferation|negative regulation of transcription regulatory region DNA binding|positive regulation of lens epithelial cell proliferation|","transcription regulatory region sequence-specific DNA binding|transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|nucleic acid binding transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription coactivator activity|RNA polymerase II transcription coactivator activity|enhancer sequence-specific DNA binding|enhancer sequence-specific DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|translation factor activity, nucleic acid binding|",9,0,0,10,-0.9,0.134,0,0,0,0.756,0,0,-1.9,1.3
ENSMUSG00000021335,SLC17A1,"solute carrier family 17 (sodium phosphate), member 1",membrane|integral component of membrane|,transport|ion transport|sodium ion transport|phosphate ion transmembrane transport|urate metabolic process|transmembrane transport|,phosphate ion transmembrane transporter activity|symporter activity|,10,-0.1,0.363,10,0,0,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000046259,SPRR2H,small proline-rich protein 2H,cornified envelope|cytoplasm|,epidermis development|keratinocyte differentiation|keratinization|,molecular_function|,10,0,0,9,0,0,0,0,0,0.756,0,0,-1.3,1.8
ENSMUSG00000043614,VPS37D,vacuolar protein sorting 37D (yeast),ESCRT I complex|endosome|membrane|extracellular vesicular exosome|,transport|protein transport|,molecular_function|,10,0,0,10,0.4,1.04,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000056770,SETD3,SET domain containing 3,nuclear chromatin|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|histone H3-K36 methylation|chromatin modification|peptidyl-lysine methylation|methylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of muscle cell differentiation|histone H3-K4 methylation|",RNA polymerase II activating transcription factor binding|transcription coactivator activity|methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H3-K4 specific)|histone methyltransferase activity (H3-K36 specific)|,10,0,0,10,-0.2,0.315,0,0,0,0.756,0,0,-2,1
ENSMUSG00000011305,PLIN5,perilipin 5,cytoplasm|mitochondrion|lipid particle|lipid particle|lipid particle|cytosol|,lipid metabolic process|positive regulation of triglyceride biosynthetic process|positive regulation of triglyceride biosynthetic process|positive regulation of lipid storage|positive regulation of sequestering of triglyceride|positive regulation of sequestering of triglyceride|negative regulation of triglyceride catabolic process|lipid storage|negative regulation of fatty acid beta-oxidation|negative regulation of fatty acid beta-oxidation|positive regulation of fatty acid beta-oxidation|positive regulation of fatty acid beta-oxidation|lipid particle organization|negative regulation of peroxisome proliferator activated receptor signaling pathway|negative regulation of lipid catabolic process|mitochondrion localization|negative regulation of lipase activity|positive regulation of lipase activity|negative regulation of reactive oxygen species metabolic process|,protein binding|lipase binding|lipase binding|identical protein binding|,10,0,0,10,0.3,1.24,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000071252,2210408I21RIK,RIKEN cDNA 2210408I21 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.165,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000034858,FAM214A,"family with sequence similarity 214, member A",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.199,10,0,0,0,0,0,0.756,0,0,-2,0.9
ENSMUSG00000032064,DIXDC1,DIX domain containing 1,cytoplasm|cytosol|cell cortex|cell junction|neuronal cell body|neuronal cell body|protein complex|axon terminus|axon terminus|,cell cycle|multicellular organismal development|Wnt signaling pathway|cerebellar cortex development|cerebellar cortex development|cerebral cortex cell migration|cerebral cortex radially oriented cell migration|cell proliferation in forebrain|forebrain ventricular zone progenitor cell division|positive regulation of Wnt signaling pathway|forebrain development|regulation of actin cytoskeleton organization|camera-type eye development|negative regulation of neuron differentiation|regulation of JNK cascade|positive regulation of JNK cascade|positive regulation of axonogenesis|positive regulation of axonogenesis|canonical Wnt signaling pathway|canonical Wnt signaling pathway|regulation of microtubule cytoskeleton organization|positive regulation of canonical Wnt signaling pathway|,actin binding|protein binding|protein domain specific binding|mitogen-activated protein kinase kinase kinase binding|mitogen-activated protein kinase kinase kinase binding|gamma-tubulin binding|gamma-tubulin binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.7,1.4
ENSMUSG00000043872,ZMYM1,"zinc finger, MYM domain containing 1",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.339,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000017561,CRLF3,cytokine receptor-like factor 3,cytoplasm|,"G1/S transition of mitotic cell cycle|negative regulation of cell growth|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of JAK-STAT cascade|positive regulation of cell cycle arrest|",molecular_function|,10,0,0,10,0.2,0.384,0,0,0,0.756,0,0,-1.7,1.3
ENSMUSG00000046753,CCDC66,coiled-coil domain containing 66,cellular_component|,retinal rod cell development|post-embryonic retina morphogenesis in camera-type eye|,molecular_function|,10,0,0,10,-0.3,0.454,0,0,0,0.756,0,0,-1.6,1.2
ENSMUSG00000022378,FAM49B,"family with sequence similarity 49, member B",cilium|extracellular vesicular exosome|,biological_process|,protein binding|,9,-0.1,0.178,9,0.1,0.174,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000044734,SERPINB1A,"serine (or cysteine) peptidase inhibitor, clade B, member 1a",extracellular space|extracellular space|cytoplasm|membrane|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|regulation of protein catabolic process|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0.1,0.0709,0,0,0,0.756,0,0,-1.6,1.4
ENSMUSG00000036931,NFKBID,"nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta",nucleus|,inflammatory response|negative regulation of NF-kappaB transcription factor activity|negative regulation of T cell differentiation in thymus|negative regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of thymocyte apoptotic process|,protein binding|NF-kappaB binding|,10,0,0,10,0.1,0.177,0,0,0,0.756,0,0,-1.7,1.3
ENSMUSG00000001229,DPP9,dipeptidylpeptidase 9,cytoplasm|membrane|,proteolysis|,aminopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|identical protein binding|,10,0,0,10,-0.5,0.744,0,0,0,0.756,0,0,-1.9,1
ENSMUSG00000011096,AKT1S1,AKT1 substrate 1 (proline-rich),nucleus|cytoplasm|cytosol|TORC1 complex|protein complex|,negative regulation of protein kinase activity|Notch signaling pathway|negative regulation of TOR signaling|regulation of neuron apoptotic process|negative regulation of cell size|neurotrophin TRK receptor signaling pathway|,None,9,0,0,9,0.3,0.444,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000056706,KRTAP7-1,keratin associated protein 7-1,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0,0,10,0.2,0.551,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000002844,ADPRH,ADP-ribosylarginine hydrolase,None,cellular protein modification process|cellular protein modification process|protein de-ADP-ribosylation|,magnesium ion binding|ADP-ribosylarginine hydrolase activity|ADP-ribosylarginine hydrolase activity|hydrolase activity|,10,0.5,1.68,9,-0.2,0.259,0,0,0,0.756,0,0,-0.9,1.9
ENSMUSG00000037503,FAM168B,"family with sequence similarity 168, member B",cellular_component|cytoplasm|plasma membrane|membrane|integral component of membrane|cell projection|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.41,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000045179,SOX3,SRY (sex determining region Y)-box 3,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|sensory organ development|sex determination|sex determination|organ morphogenesis|hypothalamus development|pituitary gland development|forebrain development|spermatid differentiation|face development|",RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II transcription corepressor activity|DNA binding|,9,0,0,9,-0.1,0.123,0,0,0,0.756,0,0,-1.6,1.5
ENSMUSG00000028539,ARTN,artemin,extracellular region|extracellular space|,cell surface receptor signaling pathway|axon guidance|axon guidance|peripheral nervous system development|induction of positive chemotaxis|Peyer's patch morphogenesis|lymphocyte migration into lymphoid organs|,receptor binding|protein binding|growth factor activity|glial cell line-derived neurotrophic factor receptor binding|glial cell line-derived neurotrophic factor receptor binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.6
ENSMUSG00000036402,GNG12,"guanine nucleotide binding protein (G protein), gamma 12",heterotrimeric G-protein complex|actin filament|plasma membrane|membrane|extracellular vesicular exosome|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|PDZ domain binding|phosphate ion binding|,10,0.1,0.103,10,0,0,0,0,0,0.756,0,0,-1.3,1.6
ENSMUSG00000047022,MIPOL1,mirror-image polydactyly gene 1 homolog (human),nucleus|,biological_process|,molecular_function|,9,0,0,9,0,0,0,0,0,0.756,0,0,-1.6,1.6
ENSMUSG00000032327,STRA6,stimulated by retinoic acid gene 6,plasma membrane|plasma membrane|membrane|integral component of membrane|protein complex|,blood vessel development|kidney development|pulmonary valve morphogenesis|ventricular septum development|transport|heart development|learning|feeding behavior|lung development|adrenal gland development|female genitalia development|retinol transport|retinol transport|vocal learning|ear development|nose morphogenesis|positive regulation of JAK-STAT cascade|lung alveolus development|positive regulation of behavior|digestive tract morphogenesis|embryonic digestive tract development|developmental growth|smooth muscle tissue development|artery morphogenesis|cognition|neuromuscular process|head development|head morphogenesis|face morphogenesis|lung vasculature development|diaphragm development|embryonic camera-type eye formation|eyelid development in camera-type eye|uterus morphogenesis|alveolar primary septum development|pulmonary artery morphogenesis|paramesonephric duct development|ductus arteriosus closure|,receptor activity|protein binding|vitamin transporter activity|,10,0,0,10,-0.4,0.889,0,0,0,0.756,0,0,-1.8,1.1
ENSMUSG00000039349,C130074G19RIK,RIKEN cDNA C130074G19 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000023467,TULP2,tubby-like protein 2,cellular_component|extracellular region|cytoplasm|,biological_process|,phosphoric diester hydrolase activity|protein complex binding|,10,0,0,10,-0.1,0.49,0,0,0,0.756,0,0,-1.8,1.2
ENSMUSG00000051246,MSANTD1,Myb/SANT-like DNA-binding domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.8,1.3
ENSMUSG00000040795,IQCC,IQ motif containing C,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.5,1.7
ENSMUSG00000009394,SYN2,synapsin II,cell|synaptic vesicle|cell junction|synaptic vesicle membrane|synapse|,neurotransmitter secretion|neurotransmitter secretion|,catalytic activity|ATP binding|protein dimerization activity|calcium-dependent protein binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.1,1.9
ENSMUSG00000015536,MOCS2,molybdenum cofactor synthesis 2,nucleus|cytoplasm|cytosol|molybdopterin synthase complex|extracellular vesicular exosome|,Mo-molybdopterin cofactor biosynthetic process|,nucleotide binding|transferase activity|molybdopterin synthase activity|molybdopterin synthase activity|identical protein binding|,10,0,0,10,-0.3,0.257,0,0,0,0.756,0,0,-2,0.8
ENSMUSG00000034158,LRRC58,leucine rich repeat containing 58,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.109,10,0,0,0,0,0,0.756,0,0,-1.3,1.7
ENSMUSG00000057191,AB124611,cDNA sequence AB124611,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.3,1.9
ENSMUSG00000052512,NAV2,neuron navigator 2,interstitial matrix|nucleus|extracellular matrix|,regulation of systemic arterial blood pressure by baroreceptor feedback|nervous system development|sensory perception of sound|sensory perception of smell|locomotory behavior|optic nerve development|glossopharyngeal nerve development|vagus nerve development|,nucleotide binding|ATP binding|heparin binding|,10,0,0,10,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000025736,JMJD8,jumonji domain containing 8,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.2,0.187,10,0,0,0,0,0,0.756,0,0,-1.4,1.5
ENSMUSG00000028392,BSPRY,B-box and SPRY domain containing,intracellular|cytoplasm|membrane|cell leading edge|perinuclear region of cytoplasm|,transport|ion transport|calcium ion transport|biological_process|,vitamin D binding|zinc ion binding|metal ion binding|,10,0,0,10,-0.1,0.365,0,0,0,0.756,0,0,-1.7,1.3
ENSMUSG00000046761,FAM83H,"family with sequence similarity 83, member H",cellular_component|,biological_process|biomineral tissue development|,molecular_function|,9,0,0,9,0,0,0,0,0,0.756,0,0,-1.4,1.6
ENSMUSG00000079015,SERPINA1C,"serine (or cysteine) peptidase inhibitor, clade A, member 1C",extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,glycoprotein binding|protease binding|endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|identical protein binding|,10,0.4,0.498,10,0,0,0,0,0,0.756,0,0,-1,1.9
ENSMUSG00000057522,SPOP,speckle-type POZ protein,nucleus|nuclear speck|Cul3-RING ubiquitin ligase complex|,glucose homeostasis|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|proteasome-mediated ubiquitin-dependent protein catabolic process|positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|positive regulation of type B pancreatic cell apoptotic process|,RNA polymerase II transcription factor binding|protein binding|ubiquitin protein ligase binding|,10,1.4,105,10,1.7,104,1.6,208,208,1.00E-05,1,1,1.4,2.1
ENSMUSG00000037089,SLC35B2,"solute carrier family 35, member B2",Golgi apparatus|membrane|integral component of membrane|,transport|signal transduction|positive regulation of I-kappaB kinase/NF-kappaB signaling|3'-phosphoadenosine 5'-phosphosulfate transport|transmembrane transport|3'-phospho-5'-adenylyl sulfate transmembrane transport|,signal transducer activity|3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity|,9,1.7,124,9,1.3,54.8,1.6,177,177,1.00E-05,1,1,1.3,2.1
ENSMUSG00000001280,SP1,trans-acting transcription factor 1,nuclear chromatin|nucleus|nucleus|cytoplasm|protein-DNA complex|,"ossification|in utero embryonic development|trophectodermal cell differentiation|liver development|embryonic placenta development|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|megakaryocyte differentiation|lung development|enucleate erythrocyte differentiation|positive regulation by host of viral transcription|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic camera-type eye morphogenesis|embryonic skeletal system development|embryonic process involved in female pregnancy|definitive hemopoiesis|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II repressing transcription factor binding|nucleic acid binding|DNA binding|DNA binding|DNA binding|double-stranded DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|protein C-terminus binding|transcription factor binding|histone acetyltransferase binding|enhancer binding|protein homodimerization activity|histone deacetylase binding|bHLH transcription factor binding|sequence-specific DNA binding|sequence-specific DNA binding|transcription regulatory region DNA binding|metal ion binding|HMG box domain binding|,10,1.8,114,10,0.9,31.5,1.7,140,140,1.00E-05,1,1,1.3,2.2
ENSMUSG00000029478,NCOR2,nuclear receptor co-repressor 2,histone deacetylase complex|chromatin|nucleus|membrane|nuclear matrix|nuclear body|nuclear body|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|in utero embryonic development|heart morphogenesis|heart morphogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|telencephalon development|cell proliferation in forebrain|forebrain development|glucose homeostasis|negative regulation of fat cell differentiation|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|white fat cell differentiation|Type I pneumocyte differentiation|Type I pneumocyte differentiation|regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter|",RNA polymerase II regulatory region DNA binding|DNA binding|chromatin binding|chromatin binding|transcription corepressor activity|transcription corepressor activity|transcription corepressor activity|transcription corepressor activity|Notch binding|protein binding|ligand-dependent nuclear receptor binding|protein complex binding|glucocorticoid receptor binding|histone deacetylase binding|retinoic acid receptor binding|sequence-specific DNA binding|retinoid X receptor binding|protein N-terminus binding|,10,1.4,58,10,1.6,67.7,1.5,125,125,1.00E-05,1,1,1.3,2.1
ENSMUSG00000022507,1810013L24RIK,RIKEN cDNA 1810013L24 gene,cellular_component|,biological_process|,molecular_function|,10,1.3,62.3,10,1.3,57.9,1.3,120,120,1.00E-05,1,1,1,1.7
ENSMUSG00000034390,CMIP,c-Maf inducing protein,cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,10,-1.2,37.7,10,-1.4,50.1,-1.3,87.1,-87.1,1.00E-05,1,1,-1.7,-1
ENSMUSG00000019808,ADAT2,"adenosine deaminase, tRNA-specific 2",cellular_component|,tRNA wobble adenosine to inosine editing|tRNA processing|biological_process|,"catalytic activity|GTP cyclohydrolase activity|tRNA-specific adenosine deaminase activity|zinc ion binding|hydrolase activity|N-cyclopropylmelamine deaminase activity|N-cyclopropylammeline deaminase activity|N-cyclopropylammelide alkylamino hydrolase activity|2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity|tRNA-specific adenosine-37 deaminase activity|archaeal-specific GTP cyclohydrolase activity|metal ion binding|tRNA-specific adenosine-34 deaminase activity|",10,1.3,70.5,10,1.3,11.8,1.3,81.8,81.8,1.00E-05,1,1,1,1.8
ENSMUSG00000048154,KMT2D,lysine (K)-specific methyltransferase 2D,nucleus|histone methyltransferase complex|,"oocyte growth|in utero embryonic development|chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of cell proliferation|chromatin modification|methylation|positive regulation of intracellular estrogen receptor signaling pathway|response to estrogen|positive regulation of transcription from RNA polymerase II promoter|oogenesis|histone H3-K4 methylation|",methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|transcription regulatory region DNA binding|metal ion binding|,10,1.2,60.1,10,0.8,21.8,1,80.3,80.3,1.00E-05,1,1,0.7,1.5
ENSMUSG00000040843,TIPRL,"TIP41, TOR signalling pathway regulator-like (S. cerevisiae)",cytoplasm|intracellular membrane-bounded organelle|,DNA damage checkpoint|negative regulation of protein phosphatase type 2A activity|,molecular_function|,10,1.2,46.9,10,0.8,33.7,0.9,79.2,79.2,1.00E-05,1,1,0.7,1.4
ENSMUSG00000059995,ATXN7L3,ataxin 7-like 3,SAGA complex|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone deubiquitination|positive regulation of transcription, DNA-templated|",transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity|metal ion binding|,10,0.8,21.5,10,1.4,58.5,1.3,76.1,76.1,1.00E-05,1,1,0.9,1.8
ENSMUSG00000027936,CRTC2,CREB regulated transcription coactivator 2,nucleus|nucleus|cytoplasm|extracellular vesicular exosome|,"gluconeogenesis|transcription, DNA-templated|regulation of transcription, DNA-templated|positive regulation of CREB transcription factor activity|glucose homeostasis|histone H3-K9 acetylation|positive regulation of transcription from RNA polymerase II promoter|protein homotetramerization|",protein binding|cAMP response element binding protein binding|,10,1.4,43.3,10,0.9,32.6,0.9,74.6,74.6,1.00E-05,1,1,0.6,1.6
ENSMUSG00000040033,STAT2,signal transducer and activator of transcription 2,nucleus|cytoplasm|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|signal transduction|",DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|calcium ion binding|protein binding|identical protein binding|,10,0.7,33.1,10,0.8,38.1,0.7,70.4,70.4,2.00E-05,1,1,0.6,1
ENSMUSG00000020284,1810043G02RIK,RIKEN cDNA 1810043G02 gene,cytoplasm|plasma membrane|,cytoskeleton organization|smoothened signaling pathway|regulation of cell shape|cell projection organization|cilium morphogenesis|,molecular_function|,9,1.1,45.5,9,1.3,22.6,1.3,67.3,67.3,2.00E-05,1,1,0.9,1.8
ENSMUSG00000026104,STAT1,signal transducer and activator of transcription 1,nuclear chromatin|nucleus|nucleus|cytoplasm|cytoplasm|axon|dendrite|,"negative regulation of endothelial cell proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|activation of cysteine-type endopeptidase activity involved in apoptotic process|signal transduction|JAK-STAT cascade|response to nutrient|blood circulation|positive regulation of cell proliferation|response to mechanical stimulus|response to bacterium|negative regulation of angiogenesis|cytokine-mediated signaling pathway|lipopolysaccharide-mediated signaling pathway|response to lipopolysaccharide|cellular response to insulin stimulus|tumor necrosis factor-mediated signaling pathway|response to cytokine|negative regulation of macrophage fusion|cellular response to interferon-beta|response to drug|negative regulation of I-kappaB kinase/NF-kappaB signaling|response to exogenous dsRNA|response to peptide hormone|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of smooth muscle cell proliferation|response to cAMP|interferon-gamma-mediated signaling pathway|interferon-gamma-mediated signaling pathway|type I interferon signaling pathway|renal tubule development|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|tumor necrosis factor receptor binding|calcium ion binding|protein binding|enzyme binding|CCR5 chemokine receptor binding|identical protein binding|protein homodimerization activity|sequence-specific DNA binding|,9,1,43.9,9,1,13.2,1,56.7,56.7,6.00E-05,1,1,0.7,1.5
ENSMUSG00000050029,RAP2C,"RAP2C, member of RAS oncogene family",cytoplasm|endosome|cytosol|plasma membrane|membrane|recycling endosome|recycling endosome membrane|extracellular vesicular exosome|,GTP catabolic process|signal transduction|small GTPase mediated signal transduction|negative regulation of cell migration|positive regulation of protein autophosphorylation|Rap protein signal transduction|regulation of protein tyrosine kinase activity|regulation of RNA biosynthetic process|,nucleotide binding|transcription coactivator activity|GTP binding|GDP binding|,10,0.7,20.6,10,0.9,32.8,0.8,52.6,52.6,0.00012,1,1,0.6,1.2
ENSMUSG00000079003,SAMD1,sterile alpha motif domain containing 1,cellular_component|extracellular region|cytoplasm|,biological_process|,molecular_function|,9,0.9,20.6,9,1.4,32.2,1.3,49.9,49.9,0.00017,1,1,0.8,1.8
ENSMUSG00000051223,BZW1,basic leucine zipper and W2 domains 1,cytoplasm|membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",poly(A) RNA binding|,10,1.8,41.9,10,1.3,4.43,1.6,45.3,45.3,0.00032,1,1,1.1,2.6
ENSMUSG00000039231,SUV39H1,suppressor of variegation 3-9 homolog 1 (Drosophila),"chromosome, centromeric region|heterochromatin|heterochromatin|nucleus|nucleus|chromatin silencing complex|chromatin silencing complex|chromosome|nuclear heterochromatin|rDNA heterochromatin|","chromatin silencing at rDNA|DNA packaging|chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|protein methylation|cell cycle|chromatin modification|peptidyl-lysine methylation|cell differentiation|methylation|histone lysine methylation|histone H3-K9 dimethylation|histone H3-K9 trimethylation|negative regulation of circadian rhythm|negative regulation of transcription, DNA-templated|rhythmic process|histone H3-K9 methylation|histone H3-K9 methylation|",transcription regulatory region sequence-specific DNA binding|protein binding|methyltransferase activity|zinc ion binding|protein methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|transferase activity|histone-lysine N-methyltransferase activity|histone-lysine N-methyltransferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity|metal ion binding|histone methyltransferase activity (H3-K9 specific)|histone methyltransferase activity (H3-K9 specific)|protein N-terminus binding|,10,-0.6,14.6,9,-1.3,35.1,-1.1,44.6,-44.6,0.00033,1,1,-1.6,-0.7
ENSMUSG00000032187,SMARCA4,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4",nuclear chromatin|heterochromatin|extracellular space|nucleus|nucleus|nuclear euchromatin|perichromatin fibrils|membrane|SWI/SNF complex|SWI/SNF complex|SWI/SNF complex|protein complex|npBAF complex|npBAF complex|nBAF complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|vasculogenesis|in utero embryonic development|blastocyst growth|blastocyst hatching|liver development|ATP catabolic process|ATP catabolic process|nucleosome assembly|nucleosome disassembly|chromatin remodeling|chromatin remodeling|methylation-dependent chromatin silencing|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|nervous system development|glial cell fate determination|heart development|DNA methylation on cytosine within a CG sequence|chromatin modification|stem cell maintenance|neurogenesis|extracellular matrix organization|keratinocyte differentiation|negative regulation of cell growth|forebrain development|hindbrain development|embryonic hindlimb morphogenesis|aortic smooth muscle cell differentiation|ATP-dependent chromatin remodeling|positive regulation of DNA binding|positive regulation by host of viral transcription|histone H3 acetylation|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|embryonic organ morphogenesis|epidermis morphogenesis|positive regulation of sequence-specific DNA binding transcription factor activity|definitive erythrocyte differentiation|heart trabecula formation|negative regulation of androgen receptor signaling pathway|lens fiber cell development|","nucleotide binding|RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II transcription coactivator activity|p53 binding|DNA binding|chromatin binding|transcription coactivator activity|transcription corepressor activity|helicase activity|protein binding|ATP binding|DNA-dependent ATPase activity|transcription factor binding|hydrolase activity|hydrolase activity, acting on acid anhydrides|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|ATPase activity|ATPase activity|Tat protein binding|nucleosomal DNA binding|protein complex binding|histone binding|protein N-terminus binding|androgen receptor binding|lysine-acetylated histone binding|",10,1.4,27.5,10,0.8,17.6,1.2,42.6,42.6,0.0004,1,1,0.5,1.9
ENSMUSG00000035370,ADAT3,"adenosine deaminase, tRNA-specific 3",cellular_component|,tRNA processing|biological_process|,molecular_function|catalytic activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.7,23,10,0.8,18.2,0.8,40.5,40.5,0.00052,1,1,0.5,1.2
ENSMUSG00000024384,IWS1,IWS1 homolog (S. cerevisiae),nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|mRNA processing|transport|RNA splicing|regulation of mRNA export from nucleus|regulation of mRNA processing|mRNA transport|regulation of histone H4 acetylation|regulation of histone H3-K36 trimethylation|",molecular_function|DNA binding|,10,1.4,34.2,10,0.7,3.82,1.2,35.7,35.7,0.00081,1,1,0.6,2.2
ENSMUSG00000020922,LSM12,LSM12 homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,1.8,31.2,10,0.5,3.58,1.6,30.6,30.6,0.00188,0,1,0.7,2.6
ENSMUSG00000004508,GAB2,growth factor receptor bound protein 2-associated protein 2,intracellular|cytoplasm|plasma membrane|membrane|protein complex|,transmembrane receptor protein tyrosine kinase signaling pathway|integrin-mediated signaling pathway|positive regulation of cell proliferation|positive regulation of signal transduction|cell migration|osteoclast differentiation|osteoclast differentiation|intracellular signal transduction|positive regulation of mast cell degranulation|phosphatidylinositol-mediated signaling|,"transmembrane receptor protein tyrosine kinase adaptor activity|protein binding|phosphatidylinositol-3,4,5-trisphosphate binding|protein domain specific binding|phosphatidylinositol-3,4-bisphosphate binding|",6,1.8,24.3,8,1,8.18,1.7,30.5,30.5,0.0019,0,1,1.2,3
ENSMUSG00000041685,FCHO2,FCH domain only 2,plasma membrane|coated pit|coated pit|membrane|clathrin-coated vesicle|clathrin-coated vesicle|clathrin-coated vesicle|,endocytosis|membrane invagination|clathrin coat assembly|clathrin-mediated endocytosis|protein localization to plasma membrane|,"phosphatidylserine binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol binding|",10,0.9,16.4,10,0.6,15,0.7,30.3,30.3,0.00197,0,1,0.4,1.1
ENSMUSG00000003423,PIH1D1,PIH1 domain containing 1,pre-snoRNP complex|,box C/D snoRNP assembly|,molecular_function|,10,0.7,16.6,10,0.9,14.2,0.8,29.9,29.9,0.00211,0,1,0.5,1.3
ENSMUSG00000024925,RNASEH2C,"ribonuclease H2, subunit C",nucleus|ribonuclease H2 complex|ribonuclease H2 complex|,RNA catabolic process|,molecular_function|,8,0.9,11.6,8,0.9,15.3,0.9,26.5,26.5,0.00408,0,0,0.7,1.6
ENSMUSG00000038174,FAM126B,"family with sequence similarity 126, member B",intracellular|,biological_process|,molecular_function|,9,1.6,24.5,9,0.5,6.33,0.5,26,26,0.00457,0,0,0.4,2.5
ENSMUSG00000008200,FNBP4,formin binding protein 4,nucleus|,biological_process|,protein binding|,10,0.7,15.5,10,0.4,10.3,0.6,24.3,24.3,0.00702,0,0,0.4,1
ENSMUSG00000060708,BLOC1S4,"biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino",intracellular|cell|cytoplasm|BLOC-1 complex|BLOC-1 complex|,anterograde axon cargo transport|neuron projection development|melanosome organization|anterograde synaptic vesicle transport|neuromuscular process controlling balance|platelet aggregation|,protein binding|,10,0.7,17.5,10,0.5,7.48,0.6,24.2,24.2,0.0072,0,0,0.4,1
ENSMUSG00000024273,2700062C07RIK,RIKEN cDNA 2700062C07 gene,cellular_component|,biological_process|,molecular_function|,8,-1.9,23.3,8,0.7,12.2,-1.9,24.2,-24.2,0.0072,0,0,-3,-1.3
ENSMUSG00000069910,SPDL1,spindle apparatus coiled-coil protein 1,"chromosome, centromeric region|kinetochore|spindle pole|condensed chromosome outer kinetochore|nucleus|chromosome|cytoplasm|cytoskeleton|",establishment of mitotic spindle orientation|cell cycle|mitotic nuclear division|mitotic metaphase plate congression|spindle checkpoint|protein localization to kinetochore|cell division|,enzyme binding|kinetochore binding|,9,0.8,16.4,9,-1.5,25.4,-1.5,22.7,-22.7,0.01,0,0,-2.7,-0.5
ENSMUSG00000037286,STAG1,stromal antigen 1,chromatin|chromatin|nucleus|chromosome|cell junction|,cell cycle|chromosome segregation|mitotic nuclear division|cell division|,chromatin binding|,10,0.4,7.16,10,0.6,15.5,0.5,21.4,21.4,0.0134,0,0,0.3,0.9
ENSMUSG00000027520,ZDBF2,"zinc finger, DBF-type containing 2",cellular_component|,biological_process|,molecular_function|,10,1.5,24.3,10,0,0,1.4,21,21,0.0147,0,0,0.8,3
ENSMUSG00000056724,NBEAL2,neurobeachin-like 2,endoplasmic reticulum|membrane|,blood coagulation|platelet formation|megakaryocyte development|wound healing|platelet alpha granule organization|,molecular_function|,10,0.7,14.3,10,0.5,7.38,0.6,20.8,20.8,0.0155,0,0,0.4,1
ENSMUSG00000030056,ISY1,ISY1 splicing factor homolog (S. cerevisiae),nucleus|spliceosomal complex|,mRNA processing|biological_process|RNA splicing|,molecular_function|,10,0.7,6.31,10,0.9,14.9,0.8,20.4,20.4,0.0172,0,0,0.3,1.3
ENSMUSG00000028195,CYR61,cysteine rich protein 61,extracellular region|,"regulation of cell growth|osteoblast differentiation|positive regulation of protein phosphorylation|intussusceptive angiogenesis|atrioventricular valve morphogenesis|apoptotic process involved in heart morphogenesis|ventricular septum development|chemotaxis|cell adhesion|cell adhesion|positive regulation of phospholipase activity|positive regulation of cell-substrate adhesion|single organismal cell-cell adhesion|extracellular matrix organization|positive regulation of cell migration|positive regulation of cell migration|positive regulation of BMP signaling pathway|positive regulation of osteoblast proliferation|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|wound healing, spreading of cells|positive regulation of cell differentiation|positive regulation of osteoblast differentiation|positive regulation of protein kinase activity|positive regulation of transcription from RNA polymerase II promoter|atrial septum morphogenesis|chondroblast differentiation|chorio-allantoic fusion|labyrinthine layer blood vessel development|positive regulation of cartilage development|regulation of ERK1 and ERK2 cascade|reactive oxygen species metabolic process|positive regulation of ceramide biosynthetic process|",integrin binding|insulin-like growth factor binding|heparin binding|growth factor binding|extracellular matrix binding|,10,1.6,22.7,10,0.4,0.21,1.6,20.3,20.3,0.0177,0,0,1,3
ENSMUSG00000051721,BC068281,cDNA sequence BC068281,cellular_component|,biological_process|,molecular_function|,10,0.5,7.07,10,0.8,14.2,0.8,19.9,19.9,0.0198,0,0,0.3,1.2
ENSMUSG00000024077,STRN,"striatin, calmodulin binding protein",protein phosphatase type 2A complex|cytoplasm|tight junction|postsynaptic density|membrane|cell projection|neuronal cell body|dendritic spine|protein complex|postsynaptic membrane|,locomotory behavior|negative regulation of cell proliferation|Wnt signaling pathway|dendrite development|,calmodulin binding|protein domain specific binding|estrogen receptor binding|protein complex binding|protein phosphatase 2A binding|armadillo repeat domain binding|,10,0.8,11.3,10,0.7,8.82,0.7,19.5,19.5,0.0222,0,0,0.5,1.3
ENSMUSG00000071451,PSMG4,"proteasome (prosome, macropain) assembly chaperone 4",cellular_component|,biological_process|,molecular_function|,8,-1,7.8,7,-1,11.8,-1,19.2,-19.2,0.0237,0,0,-1.7,-0.6
ENSMUSG00000039536,STAU1,staufen (RNA binding protein) homolog 1 (Drosophila),cytoplasm|endoplasmic reticulum|cytoplasmic stress granule|membrane|dendrite|ribonucleoprotein complex|cytoplasmic ribonucleoprotein granule|neuron projection|neuronal cell body|cell body|extracellular vesicular exosome|,intracellular mRNA localization|,RNA binding|double-stranded RNA binding|protein binding|protein phosphatase 1 binding|poly(A) RNA binding|,10,0.5,10.2,10,0.9,10.3,0.7,18.9,18.9,0.0252,0,0,0.4,1.3
ENSMUSG00000022960,DONSON,downstream neighbor of SON,cellular_component|nucleus|,multicellular organismal development|biological_process|,molecular_function|,8,-1.2,3.3,8,0.9,16.5,0.9,18.7,18.7,0.026,0,0,0.4,1.7
ENSMUSG00000022110,SUCLA2,"succinate-Coenzyme A ligase, ADP-forming, beta subunit",mitochondrion|mitochondrion|extracellular vesicular exosome|,tricarboxylic acid cycle|succinyl-CoA metabolic process|succinate metabolic process|metabolic process|,nucleotide binding|catalytic activity|succinate-CoA ligase activity|succinate-CoA ligase (ADP-forming) activity|ATP binding|ligase activity|metal ion binding|,10,-0.7,10.1,10,-1.4,9.97,-1.1,18.7,-18.7,0.026,0,0,-1.8,-0.4
ENSMUSG00000038047,HAUS6,"HAUS augmin-like complex, subunit 6",centrosome|HAUS complex|,spindle assembly|centrosome organization|,molecular_function|,8,0.8,12.5,7,1.1,7.06,1,18.6,18.6,0.0263,0,0,0.5,1.7
ENSMUSG00000037224,ZFYVE28,"zinc finger, FYVE domain containing 28",cytoplasm|endosome|cytosol|membrane|early endosome membrane|,negative regulation of epidermal growth factor-activated receptor activity|negative regulation of epidermal growth factor receptor signaling pathway|,phosphatidylinositol-3-phosphate binding|metal ion binding|,10,-1.5,21.2,10,0.4,0.883,-1.4,18.4,-18.4,0.0269,0,0,-3,-0.6
ENSMUSG00000022604,CEP97,centrosomal protein 97,cytoplasm|centrosome|microtubule organizing center|cytoskeleton|protein complex|,biological_process|cell projection organization|,molecular_function|,10,1,12,10,0.8,6.99,0.9,18.4,18.4,0.0269,0,0,0.6,1.6
ENSMUSG00000039985,FAM60A,"family with sequence similarity 60, member A",nucleus|Sin3 complex|,negative regulation of cell migration|,molecular_function|,10,-0.6,8.96,10,-0.7,9.34,-0.6,17.8,-17.8,0.0286,0,0,-1,-0.3
ENSMUSG00000039456,MORC3,microrchidia 3,nucleus|nucleoplasm|PML body|PML body|,protein phosphorylation|cell aging|post-embryonic development|peptidyl-serine phosphorylation|negative regulation of fibroblast proliferation|protein stabilization|maintenance of protein location in nucleus|,molecular_function|,8,0.9,13.8,8,0.9,4.37,0.9,17.8,17.8,0.0286,0,0,0.6,1.7
ENSMUSG00000049091,SEPHS2,selenophosphate synthetase 2,None,selenium compound metabolic process|selenium compound metabolic process|selenocysteine biosynthetic process|phosphorylation|,"nucleotide binding|catalytic activity|selenide, water dikinase activity|ATP binding|kinase activity|transferase activity|",9,0.3,1.65,9,1.1,19.6,1,17.7,17.7,0.0288,0,0,0.6,2
ENSMUSG00000002052,SUPT6,suppressor of Ty 6,nucleus|,"nucleobase-containing compound metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|mRNA processing|transport|RNA splicing|regulation of mRNA export from nucleus|regulation of DNA-templated transcription, elongation|positive regulation of transcription elongation from RNA polymerase II promoter|positive regulation of transcription elongation from RNA polymerase II promoter|regulation of isotype switching|regulation of mRNA processing|mRNA transport|regulation of muscle cell differentiation|negative regulation of histone H3-K27 methylation|negative regulation of histone H3-K27 methylation|","nucleic acid binding|DNA binding|RNA binding|protein binding|hydrolase activity, acting on ester bonds|histone binding|poly(A) RNA binding|",10,0.5,9.2,10,1,11,0.8,17.5,17.5,0.0295,0,0,0.4,1.4
ENSMUSG00000027404,SNRPB,small nuclear ribonucleoprotein B,nucleus|spliceosomal complex|U7 snRNP|U1 snRNP|U4 snRNP|U12-type spliceosomal complex|cytoplasm|cytosol|ribonucleoprotein complex|methylosome|SMN-Sm protein complex|extracellular vesicular exosome|catalytic step 2 spliceosome|histone pre-mRNA 3'end processing complex|,spliceosomal snRNP assembly|mRNA processing|RNA splicing|,RNA binding|protein binding|poly(A) RNA binding|histone pre-mRNA DCP binding|,8,1.1,18.5,8,0.2,1.77,1,17.3,17.3,0.0301,0,0,0.3,1.7
ENSMUSG00000063480,NHP2L1,NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae),plasma membrane|,single fertilization|,snoRNA binding|poly(A) RNA binding|,7,1.3,19.3,7,-0.3,0.451,1.3,16.6,16.6,0.0323,0,0,0.4,2
ENSMUSG00000024217,SNRPC,U1 small nuclear ribonucleoprotein C,nucleus|U1 snRNP|virion|viral nucleocapsid|ribonucleoprotein complex|,"spliceosomal snRNP assembly|mRNA splicing, via spliceosome|",nucleic acid binding|RNA binding|zinc ion binding|metal ion binding|,10,0.6,11.3,9,0.5,5.36,0.6,16.1,16.1,0.0336,0,0,0.3,1
ENSMUSG00000039770,YPEL5,yippee-like 5 (Drosophila),cellular_component|,biological_process|,molecular_function|,10,0.5,12.6,10,0.6,3.73,0.5,15.8,15.8,0.0344,0,0,0.3,0.9
ENSMUSG00000059518,ZNHIT1,"zinc finger, HIT domain containing 1",nucleus|nucleus|,negative regulation of transcription from RNA polymerase II promoter|regulation of histone deacetylation|regulation of T cell proliferation|negative regulation of G0 to G1 transition|,chromatin binding|histone deacetylase binding|metal ion binding|,9,0.7,8.07,9,0.8,8.03,0.8,15.7,15.7,0.0347,0,0,0.3,1.5
ENSMUSG00000020803,TXNDC17,thioredoxin domain containing 17,cytoplasm|cytosol|extracellular vesicular exosome|,tumor necrosis factor-mediated signaling pathway|oxidation-reduction process|,peroxidase activity|electron carrier activity|protein-disulfide reductase activity|,10,-0.9,5.06,10,-0.8,10.6,-0.8,15.1,-15.1,0.0363,0,0,-1.3,-0.3
ENSMUSG00000034247,PLEKHM1,"pleckstrin homology domain containing, family M (with RUN domain) member 1",cellular_component|cytoplasm|,biological_process|intracellular signal transduction|,protein binding|metal ion binding|,10,0.5,7.91,10,0.4,7.26,0.5,14.4,14.4,0.038,0,0,0.2,0.9
ENSMUSG00000069895,ATXN1L,ataxin 1-like,cellular_component|nucleus|cell projection|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|extracellular matrix organization|lung alveolus development|lung alveolus development|positive regulation of hematopoietic stem cell proliferation|",DNA binding|RNA binding|protein binding|,10,-0.3,4.61,10,-0.6,11.5,-0.5,14.4,-14.4,0.038,0,0,-1,-0.3
ENSMUSG00000019659,CCDC12,coiled-coil domain containing 12,cellular_component|,biological_process|,molecular_function|,10,1.2,10.3,10,1.5,4.47,1.3,14,14,0.0394,0,0,0.9,2.8
ENSMUSG00000002028,KMT2A,lysine (K)-specific methyltransferase 2A,nucleus|nucleus|cytoplasm|histone methyltransferase complex|MLL1 complex|,"DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|protein complex assembly|negative regulation of cell proliferation|anterior/posterior pattern specification|anterior/posterior pattern specification|chromatin modification|methylation|positive regulation of transporter activity|embryonic hemopoiesis|histone H4-K16 acetylation|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|histone H3-K4 methylation|regulation of histone H3-K4 methylation|histone H3-K4 trimethylation|positive regulation of cellular response to drug|",DNA binding|chromatin binding|protein binding|methyltransferase activity|zinc ion binding|transferase activity|histone-lysine N-methyltransferase activity|histone methyltransferase activity (H3-K4 specific)|identical protein binding|protein homodimerization activity|transcription regulatory region DNA binding|unmethylated CpG binding|metal ion binding|lysine-acetylated histone binding|,10,-0.5,9.51,10,-0.4,4.66,-0.4,13.6,-13.6,0.0408,0,0,-0.8,-0.2
ENSMUSG00000027933,INTS3,integrator complex subunit 3,nucleus|integrator complex|SOSS complex|,DNA repair|cellular response to DNA damage stimulus|mitotic cell cycle checkpoint|response to ionizing radiation|snRNA processing|,molecular_function|,10,0.7,7.55,10,0.5,6.8,0.6,13.6,13.6,0.0408,0,0,0.3,1.2
ENSMUSG00000028069,GPATCH4,G patch domain containing 4,cellular_component|,hematopoietic progenitor cell differentiation|,nucleic acid binding|poly(A) RNA binding|,10,0.4,3.88,10,0.7,10.1,0.6,13.4,13.4,0.0415,0,0,0.2,1.1
ENSMUSG00000023806,RSPH3B,radial spoke 3B homolog (Chlamydomonas),cellular_component|,biological_process|,molecular_function|,10,0.5,4.84,10,0.5,8.97,0.5,13.4,13.4,0.0415,0,0,0.2,0.9
ENSMUSG00000035093,SECISBP2L,SECIS binding protein 2-like,cellular_component|,biological_process|,poly(A) RNA binding|,10,1,13.9,10,0.3,2.6,0.5,13.3,13.3,0.0419,0,0,0.2,1.6
ENSMUSG00000020289,NPRL3,nitrogen permease regulator-like 3,cellular_component|,ventricular septum development|aorta morphogenesis|cardiac muscle tissue development|palate development|,molecular_function|GTPase activator activity|,10,-0.4,8.53,10,-0.5,5.19,-0.5,13.2,-13.2,0.0422,0,0,-0.9,-0.2
ENSMUSG00000036613,TSSC1,tumor suppressing subtransferable candidate 1,cellular_component|,biological_process|,molecular_function|,10,-0.7,4.2,10,-1,9.62,-0.9,13.1,-13.1,0.0425,0,0,-1.5,-0.4
ENSMUSG00000032846,ZSWIM6,zinc finger SWIM-type containing 6,cellular_component|,neuron projection morphogenesis|regulation of neuron migration|,molecular_function|zinc ion binding|metal ion binding|,10,0.6,13.5,10,0.2,0.956,0.5,12.7,12.7,0.0441,0,0,0.2,1
ENSMUSG00000074247,DDA1,DET1 and DDB1 associated 1,cellular_component|,biological_process|,molecular_function|,10,0.4,1.7,10,0.9,12.4,0.8,12.6,12.6,0.0446,0,0,0.3,1.6
ENSMUSG00000029034,CPSF3L,cleavage and polyadenylation specific factor 3-like,nucleus|cytoplasm|integrator complex|blood microparticle|,snRNA processing|,molecular_function|hydrolase activity|,7,0.4,6.71,7,0.8,6.85,0.7,12.1,12.1,0.0471,0,0,0.2,1.4
ENSMUSG00000032041,TIRAP,toll-interleukin 1 receptor (TIR) domain-containing adaptor protein,intracellular|cytoplasm|plasma membrane|membrane|endocytic vesicle|ruffle membrane|,immune system process|inflammatory response|signal transduction|cell surface receptor signaling pathway|cell surface receptor signaling pathway|I-kappaB kinase/NF-kappaB signaling|I-kappaB kinase/NF-kappaB signaling|activation of JUN kinase activity|response to bacterium|myeloid cell differentiation|positive regulation of B cell proliferation|response to lipopolysaccharide|regulation of interferon-beta production|regulation of interleukin-15 production|positive regulation of interleukin-12 production|positive regulation of interleukin-15 production|positive regulation of interleukin-8 production|positive regulation of interleukin-8 production|positive regulation of tumor necrosis factor production|positive regulation of tumor necrosis factor production|positive regulation of toll-like receptor 2 signaling pathway|positive regulation of toll-like receptor 3 signaling pathway|positive regulation of toll-like receptor 4 signaling pathway|TIRAP-dependent toll-like receptor 4 signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB signaling|negative regulation of growth of symbiont in host|innate immune response|regulation of innate immune response|positive regulation of innate immune response|positive regulation of interleukin-6 biosynthetic process|positive regulation of interleukin-6 biosynthetic process|positive regulation of interleukin-6 biosynthetic process|positive regulation of JNK cascade|defense response to Gram-positive bacterium|positive regulation of NF-kappaB transcription factor activity|positive regulation of NF-kappaB transcription factor activity|positive regulation of ERK1 and ERK2 cascade|3'-UTR-mediated mRNA stabilization|cellular response to bacterial lipopeptide|cellular response to lipoteichoic acid|positive regulation of neutrophil chemotaxis|positive regulation of protein homodimerization activity|positive regulation of chemokine (C-X-C motif) ligand 1 production|positive regulation of chemokine (C-X-C motif) ligand 2 production|,"protein kinase C binding|protein binding|phosphatidylinositol-4,5-bisphosphate binding|Toll-like receptor 4 binding|Toll-like receptor 2 binding|Toll-like receptor 2 binding|protein homodimerization activity|protein heterodimerization activity|protein heterodimerization activity|",10,-1.4,15.1,10,0.2,0.387,-1.4,11.9,-11.9,0.048,0,0,-2,-0.3
ENSMUSG00000021368,TBC1D7,"TBC1 domain family, member 7",cytoplasmic vesicle|,positive regulation of protein ubiquitination|negative regulation of TOR signaling|negative regulation of TOR signaling|regulation of Rab GTPase activity|activation of Rho GTPase activity|activation of Rho GTPase activity|response to growth factor|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,0.4,6.43,10,0.4,5.77,0.4,11.8,11.8,0.0486,0,0,0.2,0.8
ENSMUSG00000022982,SOD1,"superoxide dismutase 1, soluble",extracellular region|extracellular space|extracellular space|intracellular|cell|nucleus|cytoplasm|cytoplasm|mitochondrion|mitochondrion|mitochondrial intermembrane space|peroxisome|cytosol|plasma membrane|secretory granule|extracellular matrix|dense core granule|cytoplasmic vesicle|dendrite cytoplasm|neuron projection|neuronal cell body|protein complex|extracellular vesicular exosome|,activation of MAPK activity|response to reactive oxygen species|response to superoxide|response to superoxide|ovarian follicle development|positive regulation of cytokine production|retina homeostasis|myeloid cell homeostasis|myeloid cell homeostasis|glutathione metabolic process|superoxide metabolic process|superoxide metabolic process|cellular iron ion homeostasis|response to oxidative stress|response to oxidative stress|response to oxidative stress|spermatogenesis|embryo implantation|aging|cell aging|sensory perception of sound|locomotory behavior|anterograde axon cargo transport|retrograde axon cargo transport|regulation of blood pressure|response to heat|response to organic substance|transmission of nerve impulse|removal of superoxide radicals|removal of superoxide radicals|removal of superoxide radicals|removal of superoxide radicals|removal of superoxide radicals|response to nutrient levels|peripheral nervous system myelin maintenance|regulation of Rac GTPase activity|positive regulation of superoxide anion generation|regulation of multicellular organism growth|response to drug|response to hydrogen peroxide|superoxide anion generation|negative regulation of apoptotic process|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of catalytic activity|negative regulation of neuron apoptotic process|response to ethanol|negative regulation of cholesterol biosynthetic process|regulation of protein kinase activity|response to copper ion|muscle cell cellular homeostasis|response to axon injury|hydrogen peroxide biosynthetic process|hydrogen peroxide biosynthetic process|regulation of mitochondrial membrane potential|oxidation-reduction process|heart contraction|heart contraction|neurofilament cytoskeleton organization|neurofilament cytoskeleton organization|relaxation of vascular smooth muscle|auditory receptor cell stereocilium organization|reactive oxygen species metabolic process|positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,superoxide dismutase activity|superoxide dismutase activity|superoxide dismutase activity|superoxide dismutase activity|copper ion binding|copper ion binding|protein binding|zinc ion binding|zinc ion binding|antioxidant activity|oxidoreductase activity|enzyme binding|protein phosphatase 2B binding|identical protein binding|metal ion binding|Rac GTPase binding|chaperone binding|,9,0.5,11.9,9,-0.6,1.66,0.5,11.5,11.5,0.0502,0,0,0.2,1.1
ENSMUSG00000024764,NAA40,"N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)",cellular_component|,lipid metabolic process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,-0.6,4.64,10,-0.6,7.23,-0.6,11.5,-11.5,0.0502,0,0,-1.1,-0.3
ENSMUSG00000022195,6030458C11RIK,RIKEN cDNA 6030458C11 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,11.2,10,0.3,1.36,0.5,11.5,11.5,0.0502,0,0,0.2,1
ENSMUSG00000001228,UHRF1,"ubiquitin-like, containing PHD and RING finger domains, 1",nuclear chromatin|nuclear chromatin|euchromatin|heterochromatin|heterochromatin|nucleus|nucleus|nucleus|replication fork|replication fork|nuclear heterochromatin|nuclear matrix|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|DNA repair|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|cell cycle|cell proliferation|maintenance of DNA methylation|maintenance of DNA methylation|histone monoubiquitination|chromatin modification|histone ubiquitination|positive regulation of cellular protein metabolic process|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein autoubiquitination|","core promoter proximal region sequence-specific DNA binding|DNA binding|ubiquitin-protein transferase activity|ubiquitin-protein transferase activity|protein binding|zinc ion binding|methyl-CpG binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|nucleosomal histone binding|methylated histone binding|methylated histone binding|histone binding|identical protein binding|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|hemi-methylated DNA-binding|hemi-methylated DNA-binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",8,1.2,12.9,7,-0.9,2.68,1,11.5,11.5,0.0502,0,0,0.2,2
ENSMUSG00000096121,GM14474,predicted gene 14474,nucleosome|cellular_component|nucleus|chromosome|,biological_process|,molecular_function|DNA binding|,4,-0.3,1.97,4,-1.1,11.8,-1,11.3,-11.3,0.0515,0,0,-2,-0.5
ENSMUSG00000022677,FOPNL,Fgfr1op N-terminal like,nucleus|cytoplasm|centrosome|microtubule organizing center|cytoskeleton|motile cilium|centriolar satellite|ciliary basal body|cell projection|,cell projection organization|microtubule anchoring|cilium assembly|,molecular_function|,10,0.6,8.37,10,0.3,3.88,0.4,11.2,11.2,0.0522,0,0,0.2,0.9
ENSMUSG00000000902,SMARCB1,"SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1",nuclear chromosome|nuclear chromatin|XY body|nucleus|nucleus|SWI/SNF complex|SWI/SNF complex|protein complex|npBAF complex|nBAF complex|,"blastocyst development|blastocyst hatching|DNA repair|nucleosome disassembly|nucleosome disassembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|cell cycle|nervous system development|negative regulation of cell proliferation|chromatin modification|cell differentiation|single stranded viral RNA replication via double stranded DNA intermediate|ATP-dependent chromatin remodeling|ATP-dependent chromatin remodeling|positive regulation by host of viral transcription|mitotic cell cycle phase transition|positive regulation of transcription from RNA polymerase II promoter|positive regulation of sequence-specific DNA binding transcription factor activity|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|p53 binding|transcription coactivator activity|protein binding|Tat protein binding|nucleosomal DNA binding|,10,0.7,7.96,9,0.5,3.69,0.6,10.9,10.9,0.0541,0,0,0.2,1.3
ENSMUSG00000095413,GM14484,predicted gene 14484,nucleosome|cellular_component|nucleus|chromosome|,biological_process|,molecular_function|DNA binding|,3,-0.3,1.54,3,-1.1,10.9,-1,10.5,-10.5,0.0568,0,0,-2,-0.6
ENSMUSG00000004626,STXBP2,syntaxin binding protein 2,cell|cytoplasm|cytosol|plasma membrane|apical plasma membrane|apical plasma membrane|lamellipodium|secretory granule|SNARE complex|specific granule|azurophil granule|protein complex|cytolytic granule|extracellular vesicular exosome|tertiary granule|,leukocyte mediated cytotoxicity|transport|exocytosis|vesicle docking involved in exocytosis|protein transport|vesicle-mediated transport|regulation of mast cell degranulation|,syntaxin-1 binding|syntaxin-1 binding|syntaxin binding|syntaxin binding|syntaxin-3 binding|syntaxin-3 binding|,10,1,13.7,10,-0.2,0.664,1,10.5,10.5,0.0568,0,0,0.6,2
ENSMUSG00000001018,SNAPIN,SNAP-associated protein,intracellular|cell|nucleolus|cytoplasm|Golgi apparatus|cytosol|synaptic vesicle|membrane|cell junction|secretory granule|BLOC-1 complex|BLOC-1 complex|cytoplasmic vesicle|synapse|perinuclear region of cytoplasm|,intracellular protein transport|exocytosis|synaptic transmission|anterograde axon cargo transport|endosome to lysosome transport|synaptic vesicle exocytosis|synaptic vesicle maturation|neuron projection development|synaptic vesicle fusion to presynaptic membrane|regulation of protein binding|synaptic vesicle transport|anterograde synaptic vesicle transport|terminal button organization|autophagic vacuole maturation|,SNARE binding|protein binding|,10,0.4,7.1,10,0.3,3.47,0.4,10.2,10.2,0.059,0,0,0.2,0.9
ENSMUSG00000019132,BC005537,cDNA sequence BC005537,intracellular|,biological_process|,molecular_function|,9,0.8,9.54,9,0.5,1.8,0.8,10.1,10.1,0.0599,0,0,0.3,1.5
ENSMUSG00000038806,SDE2,SDE2 telomere maintenance homolog (S. pombe),cellular_component|,biological_process|,molecular_function|,10,0.4,5.13,10,0.9,7.08,0.4,10,10,0.0606,0,0,0.2,1.5
ENSMUSG00000072772,GRCC10,"gene rich cluster, C10 gene",cellular_component|cytoplasm|,biological_process|,molecular_function|,10,1.3,11.8,10,0.3,1.83,1.2,9.96,9.96,0.061,0,0,0.3,2
ENSMUSG00000036246,GMIP,Gem-interacting protein,intracellular|,signal transduction|intracellular signal transduction|,GTPase activator activity|metal ion binding|,10,-0.5,8.74,10,-0.3,1.85,-0.5,9.84,-9.84,0.062,0,0,-1,-0.2
ENSMUSG00000044768,D1ERTD622E,"DNA segment, Chr 1, ERATO Doi 622, expressed",cytoplasm|cilium|ciliary transition zone|cell projection|,transport|biological_process|protein transport|cell projection organization|,molecular_function|,10,-0.9,3.15,10,-0.6,7.6,-0.6,9.77,-9.77,0.0625,0,0,-1.4,-0.2
ENSMUSG00000044991,1110034G24RIK,RIKEN cDNA 1110034G24 gene,cellular_component|,biological_process|,molecular_function|,10,-1.4,12.7,10,0,0,-1.4,9.69,-9.69,0.0631,0,0,-2,-0.4
ENSMUSG00000019822,SMPD2,"sphingomyelin phosphodiesterase 2, neutral",intracellular|caveola|membrane|integral component of membrane|,lipid metabolic process|sphingolipid metabolic process|response to mechanical stimulus|intracellular signal transduction|positive regulation of apoptotic process|ceramide biosynthetic process|,sphingomyelin phosphodiesterase activity|sphingomyelin phosphodiesterase activity|hydrolase activity|metal ion binding|,10,0.3,3.55,10,0.9,7.96,0.3,9.66,9.66,0.0634,0,0,0.2,1.6
ENSMUSG00000012123,AIM1L,absent in melanoma 1-like,cellular_component|,biological_process|,molecular_function|,10,0.4,7.58,10,0.5,2.45,0.4,9.58,9.58,0.0641,0,0,0.2,1
ENSMUSG00000026873,PHF19,PHD finger protein 19,nucleus|ESC/E(Z) complex|ESC/E(Z) complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|stem cell maintenance|stem cell differentiation|positive regulation of histone H3-K27 methylation|positive regulation of histone H3-K27 methylation|",zinc ion binding|methylated histone binding|methylated histone binding|metal ion binding|,10,0.4,1.64,10,0.4,8.16,0.4,9.5,9.5,0.0647,0,0,0.1,0.9
ENSMUSG00000047248,C2CD3,C2 calcium-dependent domain containing 3,cytoplasm|centrosome|centriole|centriole|cytoskeleton|cilium|centriolar satellite|ciliary basal body|cell projection|,in utero embryonic development|heart looping|pattern specification process|brain development|regulation of smoothened signaling pathway|regulation of smoothened signaling pathway|protein processing|neural tube development|neural plate axis specification|cell projection organization|regulation of proteolysis|embryonic limb morphogenesis|nonmotile primary cilium assembly|cilium assembly|embryonic digit morphogenesis|protein localization to centrosome|,protein binding|,10,0.6,8.66,10,0.3,2.13,0.5,9.33,9.33,0.0661,0,0,0.1,1.1
ENSMUSG00000047213,YTHDF3,YTH domain family 3,cellular_component|,biological_process|,RNA binding|poly(A) RNA binding|N6-methyladenosine-containing RNA binding|,10,-0.5,3.63,10,-0.6,5.97,-0.5,9.22,-9.22,0.0672,0,0,-1.1,-0.2
ENSMUSG00000057147,DPH6,diphthamine biosynthesis 6,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|ligase activity|diphthine-ammonia ligase activity|,10,0.7,7.97,10,0.4,2.63,0.5,9.18,9.18,0.0675,0,0,0.2,1.3
ENSMUSG00000027615,HPS3,Hermansky-Pudlak syndrome 3 homolog (human),cytoplasm|BLOC-2 complex|,organelle organization|pigmentation|,None,10,0.2,1.58,10,0.5,8.99,0.4,9.12,9.12,0.0682,0,0,0.1,0.9
ENSMUSG00000028706,NSUN4,"NOL1/NOP2/Sun domain family, member 4",cytoplasm|mitochondrion|mitochondrial large ribosomal subunit|,rRNA processing|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.7,5.8,10,0.4,3.97,0.6,9.04,9.04,0.0691,0,0,0.2,1.4
ENSMUSG00000071540,3425401B19RIK,RIKEN cDNA 3425401B19 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,1.26,10,0.8,10.5,0.7,9.04,9.04,0.0691,0,0,0.2,1.7
ENSMUSG00000006818,SOD2,"superoxide dismutase 2, mitochondrial",intracellular|cytoplasm|mitochondrion|mitochondrion|mitochondrial inner membrane|mitochondrial nucleoid|extracellular vesicular exosome|,response to reactive oxygen species|response to superoxide|response to superoxide|age-dependent response to oxidative stress|age-dependent response to reactive oxygen species|release of cytochrome c from mitochondria|liver development|detection of oxygen|vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|glutathione metabolic process|superoxide metabolic process|superoxide metabolic process|response to oxidative stress|response to oxidative stress|mitochondrion organization|heart development|locomotory behavior|regulation of blood pressure|negative regulation of cell proliferation|intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to oxidative stress|apoptotic mitochondrial changes|post-embryonic development|response to gamma radiation|response to activity|removal of superoxide radicals|removal of superoxide radicals|removal of superoxide radicals|respiratory electron transport chain|hemopoiesis|response to nutrient levels|oxygen homeostasis|vasodilation|response to drug|response to hydrogen peroxide|superoxide anion generation|hydrogen peroxide metabolic process|negative regulation of apoptotic process|negative regulation of neuron apoptotic process|positive regulation of nitric oxide biosynthetic process|negative regulation of fat cell differentiation|negative regulation of fibroblast proliferation|neuron development|response to axon injury|erythrophore differentiation|hydrogen peroxide biosynthetic process|regulation of catalytic activity|protein homooligomerization|protein homotetramerization|regulation of mitochondrial membrane potential|iron ion homeostasis|response to hyperoxia|oxidation-reduction process|negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|,DNA binding|superoxide dismutase activity|superoxide dismutase activity|superoxide dismutase activity|protein binding|oxidoreductase activity|oxygen binding|manganese ion binding|identical protein binding|metal ion binding|,10,1.1,10.7,10,0.2,1.13,0.5,8.94,8.94,0.0701,0,0,0.2,1.8
ENSMUSG00000024078,TTC27,tetratricopeptide repeat domain 27,cellular_component|,biological_process|,molecular_function|,10,0.8,7,10,0.3,3.67,0.5,8.88,8.88,0.0707,0,0,0.2,1.4
ENSMUSG00000051154,COMMD3,COMM domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0.4,6.86,10,-0.9,3.85,0.5,8.84,8.84,0.0711,0,0,-0.3,1.6
ENSMUSG00000032415,UBE2CBP,ubiquitin-conjugating enzyme E2C binding protein,cellular_component|cytoplasm|,biological_process|,"molecular_function|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.4,3.36,10,0.3,5.82,0.4,8.69,8.69,0.0728,0,0,0.1,0.8
ENSMUSG00000027287,SNAP23,synaptosomal-associated protein 23,cell|nucleus|plasma membrane|plasma membrane|membrane|cell junction|SNARE complex|cytoplasmic vesicle|specific granule|azurophil granule|neuron projection|synapse|extracellular vesicular exosome|,protein complex assembly|transport|exocytosis|protein transport|vesicle-mediated transport|regulation of exocytosis|membrane fusion|,SNAP receptor activity|protein binding|syntaxin binding|,9,0.8,6.6,9,1.2,3.22,1,8.67,8.67,0.0731,0,0,0.5,1.9
ENSMUSG00000027811,4930579G24RIK,RIKEN cDNA 4930579G24 gene,cellular_component|,biological_process|,molecular_function|,10,0.7,9.02,10,-1.1,1.69,0.6,8.62,8.62,0.0737,0,0,0.2,1.6
ENSMUSG00000028617,LRRC42,leucine rich repeat containing 42,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.288,10,0.9,11.1,0.3,8.58,8.58,0.0742,0,0,0.2,1.8
ENSMUSG00000021671,POC5,POC5 centriolar protein homolog (Chlamydomonas),cytoplasm|centrosome|cytoskeleton|,cell cycle|biological_process|,protein binding|identical protein binding|,10,0,0,10,0.8,9.61,0.7,8.36,8.36,0.0768,0,0,0.1,1.5
ENSMUSG00000096571,1700012L04RIK,RIKEN cDNA 1700012L04 gene,nucleosome|nucleus|chromosome|,None,DNA binding|,7,-0.7,1.47,7,-1,7.75,-0.9,8.34,-8.34,0.0771,0,0,-1.9,-0.4
ENSMUSG00000047220,CCDC36,coiled-coil domain containing 36,cellular_component|,biological_process|,molecular_function|,10,-1.4,11.2,10,0.1,0.693,-1.3,8.29,-8.29,0.0777,0,0,-2,-0.2
ENSMUSG00000038291,SNX25,sorting nexin 25,endosome|membrane|,transport|protein transport|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|receptor catabolic process|receptor catabolic process|termination of G-protein coupled receptor signaling pathway|negative regulation of pathway-restricted SMAD protein phosphorylation|,type I transforming growth factor beta receptor binding|phosphatidylinositol binding|,10,0,0,10,-0.6,9.73,-0.5,8.2,-8.2,0.0792,0,0,-1.2,-0.1
ENSMUSG00000027628,AAR2,AAR2 splicing factor homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0.4,4.05,10,0.5,4.49,0.4,8.1,8.1,0.0806,0,0,0.1,1
ENSMUSG00000042157,SPRR2I,small proline-rich protein 2I,cornified envelope|cytoplasm|,epidermis development|keratinocyte differentiation|keratinization|,molecular_function|,10,0.6,9.33,10,0,0,0.5,7.99,7.99,0.0822,0,0,0.2,1.3
ENSMUSG00000000378,CCM2,cerebral cavernous malformation 2,cytoplasm|protein complex|,blood vessel development|vasculogenesis|vasculogenesis|in utero embryonic development|in utero embryonic development|endothelial cell development|endothelial cell development|vasculature development|vasculature development|heart development|heart development|heart development|multicellular organism growth|multicellular organism growth|cell-cell junction organization|inner ear development|venous blood vessel morphogenesis|venous blood vessel morphogenesis|pericardium development|pericardium development|blood vessel endothelial cell differentiation|endothelial tube morphogenesis|,protein binding|,9,-0.3,1.66,8,-0.7,8.01,-0.6,7.83,-7.83,0.0846,0,0,-1.4,-0.1
ENSMUSG00000033106,SLC7A6OS,"solute carrier family 7, member 6 opposite strand",cellular_component|nucleus|cytoplasm|,hematopoietic progenitor cell differentiation|transport|protein transport|,molecular_function|,9,0.5,5.23,9,0.4,2.9,0.5,7.79,7.79,0.0852,0,0,-0.4,1.6
ENSMUSG00000029703,LRWD1,leucine-rich repeats and WD repeat domain containing 1,"chromosome, centromeric region|chromosome, telomeric region|nucleus|nuclear origin of replication recognition complex|chromosome|centromeric heterochromatin|cytoplasm|cytoskeleton|telomeric heterochromatin|",DNA replication|chromatin organization|chromatin modification|establishment of protein localization to chromatin|,chromatin binding|methyl-CpG binding|methylated histone binding|,10,0.4,1.43,10,0.6,7.14,0.6,7.71,7.71,0.0864,0,0,0.1,1.3
ENSMUSG00000023066,RTTN,rotatin,cytoplasm|cytoskeleton|cilium|integral component of membrane|ciliary basal body|cell projection|,multicellular organismal development|determination of left/right symmetry|,None,10,0.6,9.41,10,0.1,0.382,0.6,7.65,7.65,0.0874,0,0,0.1,1.4
ENSMUSG00000037458,AZIN1,antizyme inhibitor 1,None,polyamine metabolic process|polyamine biosynthetic process|negative regulation of protein catabolic process|positive regulation of catalytic activity|positive regulation of catalytic activity|negative regulation of catalytic activity|,catalytic activity|ornithine decarboxylase inhibitor activity|ornithine decarboxylase activator activity|ornithine decarboxylase activator activity|,10,0.4,5.17,10,0.3,2.84,0.4,7.52,7.52,0.0891,0,0,0.1,1
ENSMUSG00000027245,HYPK,huntingtin interacting protein K,cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,7,-1.2,8.49,8,0.1,0.499,-1.2,7.35,-7.35,0.0918,0,0,-2,-0.3
ENSMUSG00000027742,COG6,component of oligomeric golgi complex 6,Golgi apparatus|membrane|Golgi transport complex|,transport|intra-Golgi vesicle-mediated transport|protein transport|glycosylation|,molecular_function|,10,1,9.05,10,0.2,1.72,0.9,7.32,7.32,0.0923,0,0,0,2
ENSMUSG00000021490,SLC34A1,"solute carrier family 34 (sodium phosphate), member 1",endosome|plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|intrinsic component of plasma membrane|brush border membrane|membrane-bounded vesicle|membrane raft|perinuclear region of cytoplasm|,transport|ion transport|sodium ion transport|phosphate ion transport|response to lead ion|phosphate ion transmembrane transport|sodium-dependent phosphate transport|positive regulation of membrane potential|response to cadmium ion|response to mercury ion|bone remodeling|protein homooligomerization|phosphate ion homeostasis|arsenate ion transmembrane transport|positive regulation of sodium-dependent phosphate transport|positive regulation of phosphate transmembrane transport|,protein binding|symporter activity|sodium-dependent phosphate transmembrane transporter activity|PDZ domain binding|protein complex binding|protein homodimerization activity|,10,0.5,1.02,10,0.6,6.47,0.6,7.07,7.07,0.0968,0,0,0.1,1.5
ENSMUSG00000061186,SFMBT2,Scm-like with four mbt domains 2,nucleus|,"regulation of transcription, DNA-templated|negative regulation of gene expression|",histone binding|,10,0.5,7.76,10,0,0,0.5,7.05,7.05,0.0971,0,0,0.1,1.2
ENSMUSG00000044442,N6AMT1,N-6 adenine-specific DNA methyltransferase 1 (putative),protein complex|,protein methylation|positive regulation of cell growth|methylation|,methyltransferase activity|protein methyltransferase activity|transferase activity|,10,0.9,9.84,10,0,0,0.9,6.95,6.95,0.0989,0,0,0.3,1.9
ENSMUSG00000002668,DENND1C,DENN/MADD domain containing 1C,cellular_component|cytoplasm|cytoplasmic vesicle|,positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,0.4,7.56,10,0,0,0.4,6.95,6.95,0.0989,0,0,0,1.2
ENSMUSG00000027346,GPCPD1,glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae),cytoplasm|,glycerol metabolic process|lipid metabolic process|,phosphoric diester hydrolase activity|glycerophosphodiester phosphodiesterase activity|hydrolase activity|carbohydrate binding|glycerophosphocholine phosphodiesterase activity|starch binding|,10,0.6,6.36,10,0.4,0.878,0.5,6.9,6.9,0.1,0,0,0.1,1.4
ENSMUSG00000024579,PCYOX1L,prenylcysteine oxidase 1 like,extracellular region|membrane|,prenylcysteine catabolic process|oxidation-reduction process|,"prenylcysteine oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor|",10,1.2,8.2,10,-1.1,4.09,1.1,6.82,6.82,0.102,0,0,-1,2
ENSMUSG00000098678,MROH6,maestro heat-like repeat family member 6,None,None,None,10,0.4,1.59,10,1,7.17,0.4,6.74,6.74,0.103,0,0,0.2,1.9
ENSMUSG00000046658,ZFP316,zinc finger protein 316,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,1.3,10.1,10,0,0,1.3,6.72,6.72,0.104,0,0,0.2,2
ENSMUSG00000078936,TRAPPC13,trafficking protein particle complex 13,cellular_component|,biological_process|,molecular_function|,10,-1.2,7.98,10,-0.3,1.35,-1.1,6.67,-6.67,0.105,0,0,-1.9,-0.2
ENSMUSG00000024532,1700034E13RIK,RIKEN cDNA 1700034E13 gene,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.45,10,-0.5,5.73,-0.4,6.57,-6.57,0.107,0,0,-1.3,0.3
ENSMUSG00000030714,CCDC101,coiled-coil domain containing 101,nucleus|Ada2/Gcn5/Ada3 transcription activator complex|Ada2/Gcn5/Ada3 transcription activator complex|SAGA-type complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chromatin modification|histone H3 acetylation|",methylated histone binding|,10,0.1,0.423,10,1.4,9.34,1.3,6.44,6.44,0.11,0,0,0.2,3
ENSMUSG00000002477,SNRPD1,small nuclear ribonucleoprotein D1,nucleus|nucleus|spliceosomal complex|U1 snRNP|U4 snRNP|U12-type spliceosomal complex|cytoplasm|cytosol|ribonucleoprotein complex|methylosome|pICln-Sm protein complex|SMN-Sm protein complex|catalytic step 2 spliceosome|,spliceosomal snRNP assembly|mRNA processing|RNA splicing|,poly(A) RNA binding|,6,0.5,3.66,5,0.7,3.36,0.7,6.43,6.43,0.11,0,0,0.1,1.8
ENSMUSG00000070462,MESDC1,mesoderm development candidate 1,cellular_component|,biological_process|,protein binding|,9,0.2,1.01,10,-0.6,8.45,-0.6,6.4,-6.4,0.111,0,0,-1.6,0.1
ENSMUSG00000022992,KANSL2,KAT8 regulatory NSL complex subunit 2,histone acetyltransferase complex|nucleus|,chromatin modification|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|,histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|histone acetyltransferase activity (H4-K16 specific)|,10,0.2,1.93,10,1.4,8.86,1.3,6.24,6.24,0.114,0,0,0.6,2
ENSMUSG00000016409,NKAP,NFKB activating protein,nucleus|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|Notch signaling pathway|stem cell maintenance|hemopoiesis|granulocyte differentiation|T cell differentiation in thymus|negative regulation of transcription, DNA-templated|positive regulation of alpha-beta T cell differentiation|hematopoietic stem cell proliferation|",chromatin binding|chromatin DNA binding|poly(A) RNA binding|,10,-0.9,1.42,10,0.6,5.96,0.6,6.23,6.23,0.115,0,0,-1.4,1.5
ENSMUSG00000057421,LAS1L,LAS1-like (S. cerevisiae),nucleus|cytoplasm|microtubule organizing center|membrane|MLL1 complex|,rRNA processing|biological_process|,poly(A) RNA binding|,4,0.8,7.41,3,-0.9,4.55,0.7,6.2,6.2,0.115,0,0,-1.3,2
ENSMUSG00000004085,ZAK,sterile alpha motif and leucine zipper containing kinase AZK,nucleus|cytoplasm|cytoplasm|,cell cycle checkpoint|DNA damage checkpoint|MAPK cascade|activation of MAPKK activity|protein phosphorylation|protein phosphorylation|cytoskeleton organization|cell cycle|cell cycle arrest|activation of JUN kinase activity|response to radiation|phosphorylation|intracellular signal transduction|intracellular signal transduction|positive regulation of apoptotic process|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|MAP kinase kinase kinase activity|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|metal ion binding|",10,0.4,8.21,10,0,0,0.4,6.18,6.18,0.116,0,0,0,1.2
ENSMUSG00000006423,C330007P06RIK,RIKEN cDNA C330007P06 gene,cellular_component|,biological_process|,molecular_function|,10,-1.2,3.74,10,-0.5,4.65,-0.7,6.05,-6.05,0.119,0,0,-1.8,-0.1
ENSMUSG00000030103,BHLHE40,"basic helix-loop-helix family, member e40",nucleus|nucleus|nucleolus|cytoplasm|Golgi apparatus|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|response to light stimulus|entrainment of circadian clock|circadian regulation of gene expression|circadian regulation of gene expression|entrainment of circadian clock by photoperiod|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|rhythmic process|",sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II activating transcription factor binding|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription|DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|transcription corepressor activity|protein binding|protein domain specific binding|protein homodimerization activity|bHLH transcription factor binding|MRF binding|protein heterodimerization activity|protein heterodimerization activity|protein dimerization activity|E-box binding|E-box binding|,10,0.2,0.646,10,-0.6,8.27,-0.5,6.04,-6.04,0.12,0,0,-1.4,0.1
ENSMUSG00000021457,SYK,spleen tyrosine kinase,intracellular|cell|cytoplasm|plasma membrane|membrane|B cell receptor complex|cytoplasmic vesicle|early phagosome|T cell receptor complex|protein complex|,activation of MAPK activity|activation of MAPK activity|angiogenesis|serotonin secretion|lymph vessel development|macrophage activation involved in immune response|neutrophil activation involved in immune response|leukocyte activation involved in immune response|immune system process|serotonin secretion by platelet|protein phosphorylation|leukocyte cell-cell adhesion|cell surface receptor signaling pathway|cell surface receptor signaling pathway|enzyme linked receptor protein signaling pathway|G-protein coupled receptor signaling pathway|integrin-mediated signaling pathway|activation of JUN kinase activity|regulation of platelet activation|phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|peptidyl-tyrosine phosphorylation|leukotriene biosynthetic process|signal transduction by phosphorylation|neutrophil chemotaxis|regulation of superoxide anion generation|positive regulation of cell adhesion mediated by integrin|intracellular signal transduction|intracellular signal transduction|defense response to bacterium|positive regulation of mast cell degranulation|positive regulation of mast cell degranulation|regulation of neutrophil degranulation|beta selection|innate immune response|positive regulation of interleukin-3 biosynthetic process|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|positive regulation of B cell differentiation|positive regulation of gamma-delta T cell differentiation|positive regulation of bone resorption|positive regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell proliferation|protein autophosphorylation|protein autophosphorylation|blood vessel morphogenesis|positive regulation of cytokine secretion|positive regulation of peptidyl-tyrosine phosphorylation|regulation of phagocytosis|regulation of immune response|positive regulation of calcium-mediated signaling|B cell receptor signaling pathway|regulation of ERK1 and ERK2 cascade|cellular response to molecule of fungal origin|regulation of arachidonic acid secretion|regulation of platelet aggregation|,"nucleotide binding|protein kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|non-membrane spanning protein tyrosine kinase activity|receptor signaling protein tyrosine kinase activity|integrin binding|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|protein domain specific binding|",8,0.3,2.79,8,0.3,3.57,0.3,6.04,6.04,0.12,0,0,0,1.1
ENSMUSG00000018372,CEP95,centrosomal protein 95,spindle pole|cytoplasm|centrosome|cytoskeleton|,biological_process|,molecular_function|,10,0.3,4.12,10,0.4,2.29,0.4,5.98,5.98,0.121,0,0,0,1.1
ENSMUSG00000042212,SPRR2D,small proline-rich protein 2D,cornified envelope|nucleus|cytoplasm|,epidermis development|keratinocyte differentiation|keratinization|response to estradiol|,None,10,0.4,4.4,10,0.3,1.88,0.4,5.82,5.82,0.126,0,0,-0.1,1.2
ENSMUSG00000029346,SRRD,SRR1 domain containing,cellular_component|,biological_process|rhythmic process|,molecular_function|,9,0.2,1.15,9,0.8,6.27,0.3,5.81,5.81,0.126,0,0,0.1,1.8
ENSMUSG00000066150,SLC31A1,"solute carrier family 31, member 1",cytoplasm|late endosome|plasma membrane|membrane|integral component of membrane|neuronal cell body|recycling endosome|,transport|ion transport|copper ion transport|drug transmembrane transport|cellular copper ion homeostasis|cellular copper ion homeostasis|copper ion import|copper ion import|copper ion transmembrane transport|cellular response to cisplatin|copper ion import into cell|,copper ion transmembrane transporter activity|protein binding|copper uptake transmembrane transporter activity|copper uptake transmembrane transporter activity|,10,0.2,2.34,9,0.3,3.87,0.3,5.81,5.81,0.126,0,0,-0.2,1
ENSMUSG00000000948,SNRPN,small nuclear ribonucleoprotein N,nucleus|U1 snRNP|U2 snRNP|ribonucleoprotein complex|,None,RNA binding|,10,-0.7,3.78,10,-0.6,2.33,-0.7,5.74,-5.74,0.128,0,0,-1.7,0
ENSMUSG00000035206,SPPL2B,signal peptide peptidase like 2B,lysosomal membrane|Golgi apparatus|plasma membrane|endosome membrane|membrane|integral component of membrane|Golgi-associated vesicle membrane|integral component of cytoplasmic side of endoplasmic reticulum membrane|integral component of lumenal side of endoplasmic reticulum membrane|,proteolysis|membrane protein ectodomain proteolysis|membrane protein intracellular domain proteolysis|regulation of immune response|,"aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|protein homodimerization activity|",10,1.2,8.7,10,0.1,0.165,1.2,5.72,5.72,0.128,0,0,0.1,2
ENSMUSG00000045912,C2CD4C,C2 calcium-dependent domain containing 4C,cellular_component|,biological_process|,molecular_function|,10,0.2,1.54,10,0.3,4.41,0.3,5.58,5.58,0.133,0,0,-0.1,1
ENSMUSG00000074794,ARRDC3,arrestin domain containing 3,cytoplasm|endosome|plasma membrane|,temperature homeostasis|negative regulation of heat generation|skin development|negative regulation of multicellular organismal metabolic process|positive regulation of ubiquitin-protein transferase activity|fat pad development|positive regulation of adrenergic receptor signaling pathway|negative regulation of locomotion involved in locomotory behavior|,beta-3 adrenergic receptor binding|,10,0.3,1.53,10,0.3,4.32,0.3,5.58,5.58,0.133,0,0,-0.1,1.1
ENSMUSG00000006442,SRM,spermidine synthase,None,polyamine biosynthetic process|spermidine biosynthetic process|,catalytic activity|spermidine synthase activity|transferase activity|protein homodimerization activity|,10,0.3,3.76,10,0.6,2.71,0.4,5.51,5.51,0.134,0,0,0,1.2
ENSMUSG00000003135,CNOT11,"CCR4-NOT transcription complex, subunit 11",nucleus|cytoplasm|CCR4-NOT complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of translation|biological_process|gene silencing by RNA|",molecular_function|,10,0.1,0.398,10,1.3,8.31,1.3,5.49,5.49,0.135,0,0,0.3,3
ENSMUSG00000070705,EID2B,EP300 interacting inhibitor of differentiation 2B,cellular_component|,biological_process|,molecular_function|,10,0.3,1.83,10,0.3,3.83,0.3,5.37,5.37,0.139,0,0,-0.2,1.1
ENSMUSG00000025078,NHLRC2,NHL repeat containing 2,cellular_component|,biological_process|,molecular_function|,10,-0.9,6.47,10,1,7.24,0.9,5.29,5.29,0.141,0,0,-1.2,2
ENSMUSG00000030082,SEC61A1,Sec61 alpha 1 subunit (S. cerevisiae),endoplasmic reticulum|rough endoplasmic reticulum|membrane|integral component of membrane|,SRP-dependent cotranslational protein targeting to membrane|posttranslational protein targeting to membrane|transport|endoplasmic reticulum organization|protein transport|cell growth|,ribosome binding|,8,-0.7,6.11,7,-0.2,0.132,-0.6,5.29,-5.29,0.141,0,0,-1.6,0
ENSMUSG00000001962,FAM50A,"family with sequence similarity 50, member A",nucleus|,None,poly(A) RNA binding|,8,-0.4,2.38,7,1.2,4.75,-0.5,5.27,-5.27,0.142,0,0,-1.8,1.7
ENSMUSG00000028109,HORMAD1,HORMA domain containing 1,condensed nuclear chromosome|nucleus|nucleus|chromosome|cytoplasm|,blastocyst development|meiotic nuclear division|synaptonemal complex assembly|spermatogenesis|cell differentiation|meiotic DNA double-strand break formation|oogenesis|meiotic sister chromatid cohesion|meiotic recombination checkpoint|regulation of homologous chromosome segregation|,protein binding|,10,-0.4,3.55,10,-0.4,1.97,-0.4,5.24,-5.24,0.143,0,0,-1.4,0.1
ENSMUSG00000022422,DSCC1,defective in sister chromatid cohesion 1 homolog (S. cerevisiae),"chromosome, centromeric region|chromatin|nucleus|nucleoplasm|",DNA replication|regulation of DNA replication|cell cycle|maintenance of mitotic sister chromatid cohesion|post-translational protein acetylation|,molecular_function|DNA binding|,10,-1.2,5.6,10,-0.3,1.99,-0.4,5.19,-5.19,0.145,0,0,-1.9,-0.1
ENSMUSG00000021701,PLK2,polo-like kinase 2,intracellular|cytoplasm|centrosome|centriole|cytoskeleton|dendrite|cell projection|,G1/S transition of mitotic cell cycle|mitotic cell cycle|protein phosphorylation|protein phosphorylation|mitotic spindle organization|mitotic cell cycle checkpoint|Ras protein signal transduction|memory|phosphorylation|positive regulation of protein binding|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|Rap protein signal transduction|negative regulation of apoptotic process|positive regulation of I-kappaB kinase/NF-kappaB signaling|regulation of centriole replication|regulation of synaptic plasticity|regulation of synaptic plasticity|long-term synaptic potentiation|long term synaptic depression|negative regulation of dendritic spine development|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|signal transducer activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein complex binding|",10,0.3,1.8,10,0.4,3.67,0.3,5.14,5.14,0.146,0,0,-0.1,1.2
ENSMUSG00000025268,MAGED2,"melanoma antigen, family D, 2",membrane|,biological_process|,molecular_function|,10,0.9,5.05,10,0.6,0.755,0.8,5.09,5.09,0.148,0,0,0.1,1.8
ENSMUSG00000028801,STPG1,sperm tail PG rich repeat containing 1,cellular_component|nucleus|cytoplasm|,apoptotic process|biological_process|,molecular_function|,10,0.2,1.01,10,0.3,4.44,0.3,5.05,5.05,0.15,0,0,-0.2,1.2
ENSMUSG00000047044,D030056L22RIK,RIKEN cDNA D030056L22 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,2.56,10,0.3,3.14,0.3,5.03,5.03,0.151,0,0,-0.1,1.2
ENSMUSG00000020978,KLHDC2,kelch domain containing 2,cellular_component|nucleus|,biological_process|,protein binding|,10,0,0,10,-0.5,6.53,-0.4,5.02,-5.02,0.151,0,0,-1.4,0
ENSMUSG00000020898,CTC1,CTS telomere maintenance complex component 1,"chromosome, telomeric region|nuclear chromosome, telomeric region|nuclear chromosome, telomeric region|nucleus|nucleus|chromosome|Stn1-Ten1 complex|",telomere maintenance|cellular response to DNA damage stimulus|aging|regulation of G2/M transition of mitotic cell cycle|telomere maintenance via telomere lengthening|multicellular organism growth|positive regulation of DNA replication|positive regulation of fibroblast proliferation|spleen development|thymus development|bone marrow development|chromosome organization|hematopoietic stem cell proliferation|replicative senescence|,DNA binding|single-stranded DNA binding|protein binding|,9,-0.6,4.47,8,-0.3,1.49,-0.6,4.98,-4.98,0.152,0,0,-1.6,0.1
ENSMUSG00000040340,1700019B03RIK,RIKEN cDNA 1700019B03 gene,cellular_component|,biological_process|,molecular_function|,10,-0.9,1.58,10,-0.4,4.27,-0.3,4.97,-4.97,0.153,0,0,-1.6,0.6
ENSMUSG00000028608,0610037L13RIK,RIKEN cDNA 0610037L13 gene,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.5,7.39,10,-0.8,7.06,0.5,4.89,4.89,0.155,0,0,-1.7,1.2
ENSMUSG00000025184,R3HCC1L,R3H domain and coiled-coil containing 1 like,exon-exon junction complex|,biological_process|,nucleotide binding|molecular_function|,10,0.2,1.17,10,0.4,4.48,0.4,4.89,4.89,0.155,0,0,-0.1,1.2
ENSMUSG00000071037,CAMKMT,calmodulin-lysine N-methyltransferase,cellular_component|nucleus|cytoplasm|Golgi apparatus|,biological_process|methylation|,molecular_function|methyltransferase activity|transferase activity|calmodulin-lysine N-methyltransferase activity|,10,0.4,6.94,10,0,0,0.4,4.86,4.86,0.157,0,0,-0.2,1.3
ENSMUSG00000074405,ZFP865,zinc finger protein 865,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|DNA binding|metal ion binding|,10,-0.5,2.02,10,-0.6,3.15,-0.6,4.82,-4.82,0.158,0,0,-1.5,0.1
ENSMUSG00000031781,CIAPIN1,cytokine induced apoptosis inhibitor 1,nucleus|nucleolus|cytoplasm|cytoplasm|mitochondrion|,apoptotic process|iron-sulfur cluster assembly|hemopoiesis|negative regulation of apoptotic process|,"protein binding|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,1.2,7.65,9,-0.2,0.203,1.2,4.8,4.8,0.159,0,0,0.1,2
ENSMUSG00000034300,FAM53C,"family with sequence similarity 53, member C",cellular_component|,biological_process|,molecular_function|,10,0.6,5.35,10,0.2,1.06,0.4,4.79,4.79,0.159,0,0,-0.1,1.4
ENSMUSG00000038598,AI481877,expressed sequence AI481877,cellular_component|,biological_process|,molecular_function|,10,0.4,3.31,10,0.3,2.03,0.3,4.78,4.78,0.16,0,0,-0.1,1.3
ENSMUSG00000018541,CWC25,CWC25 spliceosome-associated protein homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0.9,2.42,10,0.6,2.84,0.7,4.7,4.7,0.163,0,0,0,1.8
ENSMUSG00000029291,RUFY3,RUN and FYVE domain containing 3,filopodium|growth cone|cell projection|,multicellular organismal development|nervous system development|cell differentiation|negative regulation of axonogenesis|,protein binding|,10,0.2,1.62,10,0.3,3.3,0.3,4.63,4.63,0.165,0,0,-0.2,1.1
ENSMUSG00000049489,FAM58B,"family with sequence similarity 58, member B",cellular_component|,"regulation of cyclin-dependent protein serine/threonine kinase activity|regulation of transcription, DNA-templated|positive regulation of MAPK cascade|positive regulation of protein kinase activity|",protein binding|protein kinase binding|protein kinase activator activity|,10,0.7,4.56,7,0.4,0.723,0.7,4.63,4.63,0.165,0,0,-0.2,1.9
ENSMUSG00000038930,RCCD1,RCC1 domain containing 1,cytoplasm|plasma membrane|,biological_process|,molecular_function|,9,-0.4,2.48,10,-1.1,4.89,-0.6,4.62,-4.62,0.166,0,0,-2,0.1
ENSMUSG00000033405,NUDT15,nudix (nucleoside diphosphate linked moiety X)-type motif 15,cellular_component|,response to reactive oxygen species|GTP catabolic process|dGTP catabolic process|purine deoxyribonucleoside triphosphate catabolic process|,"8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|hydrolase activity|8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity|metal ion binding|",10,-0.5,1.3,10,-0.6,3.62,-0.5,4.58,-4.58,0.168,0,0,-1.6,0.2
ENSMUSG00000035399,OSER1,oxidative stress responsive serine rich 1,cellular_component|,biological_process|cellular response to hydrogen peroxide|,molecular_function|,10,0.4,1.51,10,0.9,4.78,0.8,4.58,4.58,0.168,0,0,0.1,2
ENSMUSG00000071112,B230216G23RIK,RIKEN cDNA B230216G23 gene,extracellular space|cytoplasm|,positive regulation of systemic arterial blood pressure|negative regulation of heart rate|negative regulation of appetite|negative regulation of renal sodium excretion|long-chain fatty acid import|positive regulation of transcription from RNA polymerase II promoter|regulation of sensory perception of pain|,neuropeptide hormone activity|type 2 galanin receptor binding|type 3 galanin receptor binding|,10,0.2,1.28,10,0.6,4.51,0.2,4.55,4.55,0.169,0,0,-0.1,1.4
ENSMUSG00000049659,AFTPH,aftiphilin,cytoplasm|cytosol|AP-1 adaptor complex|,transport|biological_process|protein transport|,clathrin binding|,10,0.3,1.98,10,0.2,2.94,0.3,4.53,4.53,0.17,0,0,-0.2,1.2
ENSMUSG00000078346,GM5132,predicted gene 5132,nucleosome|cellular_component|nucleus|chromosome|,biological_process|,molecular_function|DNA binding|,10,-0.3,1.47,10,-0.5,3.47,-0.4,4.42,-4.42,0.175,0,0,-1.5,0.1
ENSMUSG00000037594,BC022687,cDNA sequence BC022687,cellular_component|,biological_process|,molecular_function|,10,0.7,5.94,10,0.1,0.0122,0.6,4.41,4.41,0.175,0,0,0,1.7
ENSMUSG00000027867,SPAG17,sperm associated antigen 17,nucleus|cytoplasm|cytoskeleton|microtubule|cilium|sperm flagellum|cell projection|,biological_process|,protein binding|,10,-1,6.55,10,-0.1,0.289,-0.4,4.35,-4.35,0.178,0,0,-1.9,-0.1
ENSMUSG00000038605,SAMD10,sterile alpha motif domain containing 10,cellular_component|,biological_process|,molecular_function|,10,0.2,1.82,10,0.5,3.26,0.4,4.34,4.34,0.178,0,0,-0.4,1.4
ENSMUSG00000010554,METTL16,methyltransferase like 16,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|poly(A) RNA binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",8,-0.8,6.11,9,0.2,1.62,-0.8,4.27,-4.27,0.182,0,0,-1.9,0.7
ENSMUSG00000024067,DPY30,dpy-30 homolog (C. elegans),nucleus|Golgi apparatus|trans-Golgi network|histone methyltransferase complex|Set1C/COMPASS complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|endosomal transport|chromatin modification|histone H3-K4 methylation|",identical protein binding|protein homodimerization activity|,10,0.3,2.9,9,0.2,1.59,0.2,4.23,4.23,0.184,0,0,-0.5,1.1
ENSMUSG00000018433,NOL11,nucleolar protein 11,nucleus|nucleolus|t-UTP complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|rRNA processing|maturation of SSU-rRNA|positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|",poly(A) RNA binding|,8,-1,1.95,6,0.5,5.99,0.5,4.2,4.2,0.185,0,0,-1.2,2
ENSMUSG00000020272,STK10,serine/threonine kinase 10,plasma membrane|membrane|extracellular vesicular exosome|,protein phosphorylation|cell cycle|phosphorylation|signal transduction by phosphorylation|protein autophosphorylation|lymphocyte aggregation|regulation of lymphocyte migration|regulation of lymphocyte migration|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|protein homodimerization activity|",9,0.2,1.09,9,0.8,4.25,0.2,4.19,4.19,0.186,0,0,-0.3,1.9
ENSMUSG00000026650,MEIG1,meiosis expressed gene 1,nucleus|,meiotic nuclear division|spermatogenesis|cell differentiation|,protein binding|,10,-0.6,5.36,10,-0.1,0.392,-0.5,4.15,-4.15,0.188,0,0,-1.5,0.7
ENSMUSG00000026851,BC005624,cDNA sequence BC005624,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.7,6.44,10,0,0,0.6,4.14,4.14,0.188,0,0,-0.1,1.8
ENSMUSG00000021395,SPIN1,spindlin 1,nucleus|nucleolus|cytoplasm|spindle|cytoskeleton|,cell cycle|meiotic nuclear division|female meiotic division|multicellular organismal development|gamete generation|rRNA transcription|Wnt signaling pathway|chromatin modification|positive regulation of Wnt signaling pathway|,DNA binding|methylated histone binding|,10,0.1,0.593,10,0.3,4.11,0.3,4.08,4.08,0.191,0,0,-0.2,1.2
ENSMUSG00000004994,CCDC130,coiled-coil domain containing 130,cellular_component|,biological_process|,molecular_function|,10,0.3,2.41,10,0.4,2.09,0.3,4.04,4.04,0.193,0,0,-0.2,1.2
ENSMUSG00000029401,RILPL2,Rab interacting lysosomal protein-like 2,intracellular|cell|cytoplasm|centrosome|cytoskeleton|cilium|cell projection|extracellular vesicular exosome|primary cilium|,epithelial cell morphogenesis|transport|intracellular protein transport|protein transport|,identical protein binding|,10,-0.1,0.0385,10,-0.7,6.12,-0.4,4.03,-4.03,0.194,0,0,-1.8,0
ENSMUSG00000003068,STK11,serine/threonine kinase 11,nucleus|nucleus|cytoplasm|cytoplasm|cytoplasm|mitochondrion|cytosol|membrane|TCR signalosome|protein complex|extracellular vesicular exosome|,regulation of cell growth|tissue homeostasis|vasculature development|protein phosphorylation|protein phosphorylation|autophagy|apoptotic process|cellular response to DNA damage stimulus|cell cycle|cell cycle arrest|spermatid development|axonogenesis|axonogenesis|negative regulation of cell proliferation|response to ionizing radiation|phosphorylation|establishment of cell polarity|regulation of Wnt signaling pathway|negative regulation of cell growth|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signaling pathway|activation of protein kinase activity|activation of protein kinase activity|response to lipid|TCR signalosome assembly|glucose homeostasis|anoikis|positive thymic T cell selection|positive regulation of gluconeogenesis|positive regulation of protein kinase activity|protein autophosphorylation|protein autophosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of axonogenesis|T cell receptor signaling pathway|T cell receptor signaling pathway|protein heterooligomerization|Golgi localization|regulation of protein kinase B signaling|canonical Wnt signaling pathway|negative regulation of epithelial cell proliferation involved in prostate gland development|intrinsic apoptotic signaling pathway by p53 class mediator|,"nucleotide binding|magnesium ion binding|p53 binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|LRR domain binding|protein kinase activator activity|protein kinase activator activity|protein kinase activator activity|protein complex binding|metal ion binding|",7,-0.3,2.5,8,-0.4,1.76,-0.4,4,-4,0.195,0,0,-1.6,0.2
ENSMUSG00000020807,4933427D14RIK,RIKEN cDNA 4933427D14 gene,cytoplasm|centrosome|,biological_process|,molecular_function|,9,0.2,0.781,10,0.6,4.32,0.5,3.99,3.99,0.196,0,0,-0.2,1.5
ENSMUSG00000063511,SNRNP70,small nuclear ribonucleoprotein 70 (U1),nucleus|nucleus|spliceosomal complex|U1 snRNP|virion|viral nucleocapsid|ribonucleoprotein complex|,"mRNA splicing, via spliceosome|regulation of RNA splicing|",nucleotide binding|nucleic acid binding|RNA binding|poly(A) RNA binding|,10,-0.5,1.91,10,-0.9,2.95,-0.6,3.99,-3.99,0.196,0,0,-1.9,0.8
ENSMUSG00000050555,HYLS1,hydrolethalus syndrome 1,nucleus|cytoplasm|cytoplasm|centrosome|plasma membrane|,biological_process|,molecular_function|,10,0.3,2.53,10,0.4,1.88,0.3,3.98,3.98,0.196,0,0,-0.3,1.3
ENSMUSG00000034042,GPBP1L1,GC-rich promoter binding protein 1-like 1,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|positive regulation of transcription, DNA-templated|",molecular_function|DNA binding|sequence-specific DNA binding transcription factor activity|,10,0.5,0.906,10,0.7,3.44,0.6,3.97,3.97,0.197,0,0,-0.1,1.7
ENSMUSG00000038637,LRRC56,leucine rich repeat containing 56,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.5,6.25,-0.5,3.96,-3.96,0.197,0,0,-1.7,0.1
ENSMUSG00000056952,TATDN2,TatD DNase domain containing 2,intracellular organelle|,DNA catabolic process|nucleic acid phosphodiester bond hydrolysis|,deoxyribonuclease activity|,10,0.2,1.92,10,0.2,2.25,0.2,3.93,3.93,0.199,0,0,-0.5,1.2
ENSMUSG00000032902,SLC16A1,"solute carrier family 16 (monocarboxylic acid transporters), member 1",mitochondrion|centrosome|plasma membrane|integral component of plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,lipid metabolic process|transport|organic anion transport|response to food|lactate transmembrane transport|plasma membrane lactate transport|glucose homeostasis|regulation of insulin secretion|centrosome organization|behavioral response to nutrient|transmembrane transport|cellular response to organic cyclic compound|,symporter activity|secondary active monocarboxylate transmembrane transporter activity|protein homodimerization activity|organic cyclic compound binding|,10,0.9,2.26,10,-0.5,2.42,0.9,3.81,3.81,0.206,0,0,-0.7,2
ENSMUSG00000023075,AKIRIN1,akirin 1,nucleus|nuclear membrane|,biological_process|,molecular_function|,10,-0.9,4.41,10,-0.5,0.916,-0.8,3.81,-3.81,0.206,0,0,-2,0.5
ENSMUSG00000042404,DENND4B,DENN/MADD domain containing 4B,nucleus|Golgi apparatus|,regulation of Rab protein signal transduction|positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.3,1.29,10,-0.3,2.73,-0.3,3.79,-3.79,0.207,0,0,-1.4,0.7
ENSMUSG00000030689,INO80E,INO80 complex subunit E,nucleus|nucleolus|Ino80 complex|,biological_process|,molecular_function|,10,0.2,1.13,10,0.4,3.29,0.3,3.71,3.71,0.211,0,0,-0.3,1.4
ENSMUSG00000031634,UFSP2,UFM1-specific peptidase 2,nucleus|cytoplasm|endoplasmic reticulum|,proteolysis|,peptidase activity|cysteine-type peptidase activity|hydrolase activity|thiolester hydrolase activity|small conjugating protein-specific protease activity|,10,0.4,1.64,10,0.5,2.25,0.5,3.62,3.62,0.216,0,0,-0.5,1.5
ENSMUSG00000042423,FBRS,fibrosin,extracellular space|,positive regulation of fibroblast proliferation|,growth factor activity|,10,0.4,2.4,10,0.4,1.44,0.4,3.61,3.61,0.217,0,0,-0.1,1.5
ENSMUSG00000031402,MPP1,"membrane protein, palmitoylated",intracellular|membrane|membrane|cortical cytoskeleton|cell projection|,regulation of neutrophil chemotaxis|,protein binding|,10,0,0,10,0.6,5.38,0.2,3.6,3.6,0.218,0,0,-0.1,1.6
ENSMUSG00000079165,SAP25,sin3 associated polypeptide,cellular_component|nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",protein binding|,10,-0.5,1.52,10,-0.5,2.29,-0.5,3.58,-3.58,0.219,0,0,-1.6,0.4
ENSMUSG00000030929,ERI2,exoribonuclease 2,cellular_component|,biological_process|,molecular_function|nucleic acid binding|nuclease activity|exonuclease activity|zinc ion binding|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,-0.8,4.93,10,0.2,1.51,-0.7,3.54,-3.54,0.222,0,0,-1.7,0.6
ENSMUSG00000025420,KATNAL2,katanin p60 subunit A-like 2,cellular_component|cytoplasm|cytoskeleton|microtubule|,biological_process|,nucleotide binding|molecular_function|ATP binding|microtubule-severing ATPase activity|hydrolase activity|,10,-0.2,0.757,10,0.4,4.8,0.4,3.54,3.54,0.222,0,0,-0.6,1.4
ENSMUSG00000028848,GPN2,GPN-loop GTPase 2,cellular_component|,biological_process|,nucleotide binding|molecular_function|GTP binding|,3,-0.8,2.73,4,-0.4,1.6,-0.7,3.5,-3.5,0.224,0,0,-2,0.4
ENSMUSG00000014873,SURF2,surfeit gene 2,nucleus|nucleolus|plasma membrane|,biological_process|,molecular_function|,10,-0.3,2.33,10,-0.2,1.4,-0.3,3.49,-3.49,0.225,0,0,-1.4,0.5
ENSMUSG00000040339,FAM102B,"family with sequence similarity 102, member B",cellular_component|,biological_process|,molecular_function|,10,-0.2,2.02,10,0.4,3.05,-0.3,3.49,-3.49,0.225,0,0,-1.3,1
ENSMUSG00000025323,SP4,trans-acting transcription factor 4,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of heart contraction|",nucleic acid binding|DNA binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.6,2.78,10,0.7,0.957,0.7,3.49,3.49,0.225,0,0,-0.7,1.8
ENSMUSG00000029174,TBC1D1,"TBC1 domain family, member 1",nucleus|,regulation of Rab GTPase activity|regulation of protein localization|,GTPase activator activity|Rab GTPase activator activity|,10,-0.2,1.35,10,-0.3,2.49,-0.3,3.44,-3.44,0.228,0,0,-1.3,0.8
ENSMUSG00000056121,FEZ2,fasciculation and elongation protein zeta 2 (zygin II),cellular_component|,biological_process|,protein binding|,10,0.3,2.97,10,0.2,0.676,0.3,3.44,3.44,0.228,0,0,-0.3,1.3
ENSMUSG00000078630,TOMT,transmembrane O-methyltransferase,cellular_component|cytoplasm|,catecholamine metabolic process|sensory perception of sound|methylation|neurotransmitter catabolic process|catecholamine catabolic process|auditory receptor cell development|,methyltransferase activity|O-methyltransferase activity|catechol O-methyltransferase activity|transferase activity|,10,-0.4,1.23,10,-0.3,2.46,-0.3,3.44,-3.44,0.228,0,0,-1.1,1.2
ENSMUSG00000024019,CMTR1,cap methyltransferase 1,nucleus|cytoplasm|,7-methylguanosine mRNA capping|mRNA processing|methylation|mRNA methylation|cap1 mRNA methylation|,nucleic acid binding|mRNA (nucleoside-2'-O-)-methyltransferase activity|methyltransferase activity|transferase activity|,10,0.4,5.71,10,-0.7,4.56,0.4,3.4,3.4,0.23,0,0,-1.7,0.9
ENSMUSG00000039337,TEX19.2,testis expressed gene 19.2,nucleus|cytoplasm|,meiotic nuclear division|spermatogenesis|biological_process|cell differentiation|,protein binding|,10,-0.1,0.0845,10,0.6,6.29,0.6,3.4,3.4,0.23,0,0,-0.6,2
ENSMUSG00000030231,PLEKHA5,"pleckstrin homology domain containing, family A member 5",cytosol|membrane|,reproductive system development|,"phosphatidylinositol-5-phosphate binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-4-phosphate binding|phosphatidylinositol-3,5-bisphosphate binding|",10,0.6,2.73,10,-0.3,1.68,-0.3,3.39,-3.39,0.231,0,0,-1.1,1.4
ENSMUSG00000028115,BNIPL,BCL2/adenovirus E1B 19kD interacting protein like,nucleus|cytosol|cytosol|,apoptotic process|apoptotic process|negative regulation of cell proliferation|regulation of growth rate|,identical protein binding|identical protein binding|,10,0.4,4.05,10,-0.7,0.753,0.4,3.39,3.39,0.231,0,0,-1,1.6
ENSMUSG00000027189,TRIM44,tripartite motif-containing 44,intracellular|,None,zinc ion binding|metal ion binding|,10,0.3,3.3,10,0.2,0.532,0.3,3.34,3.34,0.234,0,0,-0.4,1.3
ENSMUSG00000024223,ARMC12,armadillo repeat containing 12,nucleus|,biological_process|,molecular_function|,10,0.6,1.89,10,0.3,2.39,0.4,3.29,3.29,0.237,0,0,-0.2,1.6
ENSMUSG00000059013,SH2D3C,SH2 domain containing 3C,cytoplasm|membrane|,signal transduction|transmembrane receptor protein tyrosine kinase signaling pathway|small GTPase mediated signal transduction|positive regulation of signal transduction|,transmembrane receptor protein tyrosine kinase adaptor activity|guanyl-nucleotide exchange factor activity|,10,0.2,0.614,10,0.8,4.27,0.2,3.27,3.27,0.238,0,0,-0.1,1.9
ENSMUSG00000024966,STIP1,stress-induced phosphoprotein 1,nucleus|cytoplasm|protein complex|,None,protein binding|protein C-terminus binding|Hsp70 protein binding|poly(A) RNA binding|chaperone binding|,9,-0.5,1.45,8,0.6,2.79,0.5,3.26,3.26,0.239,0,0,-1.7,1.3
ENSMUSG00000046591,TICRR,TOPBP1-interacting checkpoint and replication regulator,nucleus|,DNA replication|DNA repair|cellular response to DNA damage stimulus|cell cycle|response to ionizing radiation|regulation of DNA-dependent DNA replication initiation|mitotic DNA replication checkpoint|,chromatin binding|,9,-0.4,3.54,9,-0.2,0.052,-0.4,3.24,-3.24,0.241,0,0,-1.5,0.9
ENSMUSG00000002014,SSR4,"signal sequence receptor, delta",endoplasmic reticulum|Sec61 translocon complex|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.2,1.09,10,-1.1,4.81,-0.5,3.24,-3.24,0.241,0,0,-1.9,0
ENSMUSG00000051457,SPN,sialophorin,uropod|basement membrane|extracellular space|integral component of plasma membrane|microvillus|external side of plasma membrane|cell surface|membrane|integral component of membrane|cleavage furrow|extracellular vesicular exosome|,response to protozoan|negative regulation of type IV hypersensitivity|positive regulation of protein phosphorylation|negative regulation of cell adhesion|negative regulation of cell adhesion|cell surface receptor signaling pathway|T cell costimulation|positive regulation of T cell proliferation|negative regulation of T cell proliferation|positive regulation of tumor necrosis factor biosynthetic process|positive regulation of tumor necrosis factor biosynthetic process|defense response to bacterium|defense response to bacterium|negative thymic T cell selection|regulation of defense response to virus|regulation of immune response|negative regulation of T cell activation|thymocyte aggregation|apoptotic signaling pathway|,protein binding|protein domain specific binding|,10,-0.3,1.48,10,0.4,4.68,0.3,3.24,3.24,0.241,0,0,-0.8,1.5
ENSMUSG00000042532,GOLGA7B,"golgi autoantigen, golgin subfamily a, 7B",cellular_component|Golgi apparatus|membrane|,biological_process|,molecular_function|,10,0.2,0.459,10,0.2,2.89,0.2,3.17,3.17,0.245,0,0,-1,1.3
ENSMUSG00000024528,SRFBP1,serum response factor binding protein 1,nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",protein binding|poly(A) RNA binding|,10,-0.5,3.16,10,0.7,0.272,0.7,3.16,3.16,0.246,0,0,-0.9,1.9
ENSMUSG00000041319,THOC6,THO complex 6 homolog (Drosophila),transcription export complex|THO complex|THO complex part of transcription export complex|nucleus|,mRNA processing|mRNA export from nucleus|transport|apoptotic process|multicellular organismal development|central nervous system development|RNA splicing|negative regulation of apoptotic process|viral mRNA export from host cell nucleus|mRNA transport|,RNA binding|protein binding|,10,0.2,1.44,10,0.3,2.19,0.3,3.15,3.15,0.247,0,0,-0.4,1.4
ENSMUSG00000022671,MZT2,mitotic spindle organizing protein 2,cytoplasm|centrosome|cytoskeleton|,biological_process|,molecular_function|,10,-0.4,3.6,10,0.1,0.0699,-0.4,3.14,-3.14,0.247,0,0,-1.4,0.5
ENSMUSG00000079304,4933413G19RIK,RIKEN cDNA 4933413G19 gene,cellular_component|,biological_process|,molecular_function|,10,-0.4,3.05,10,-0.2,0.578,-0.3,3.12,-3.12,0.249,0,0,-1.5,0.3
ENSMUSG00000020257,WDR82,WD repeat domain containing 82,chromatin|nucleus|histone methyltransferase complex|Set1C/COMPASS complex|PTW/PP1 phosphatase complex|,histone H3-K4 methylation|histone H3-K4 methylation|,chromatin binding|histone methyltransferase activity (H3-K4 specific)|,7,0.3,1.04,7,-0.9,2.38,0.3,3.12,3.12,0.249,0,0,-2,0.9
ENSMUSG00000051890,KLHDC1,kelch domain containing 1,cytoplasm|,biological_process|,molecular_function|,10,0.4,4.88,10,-0.1,0.0446,0.3,3.1,3.1,0.25,0,0,-0.9,1.5
ENSMUSG00000095655,GM14479,predicted gene 14479,cellular_component|,biological_process|,molecular_function|,2,-0.4,1.99,2,-0.4,1.3,-0.4,3.08,-3.08,0.251,0,0,-2,1.1
ENSMUSG00000095445,GM14475,predicted gene 14475,cellular_component|,biological_process|,molecular_function|,2,-0.4,1.99,2,-0.4,1.3,-0.4,3.08,-3.08,0.251,0,0,-2,1.1
ENSMUSG00000095208,GM14483,predicted gene 14483,cellular_component|,biological_process|,molecular_function|,2,-0.4,1.99,2,-0.4,1.3,-0.4,3.08,-3.08,0.251,0,0,-2,1.1
ENSMUSG00000044120,OLFR683,olfactory receptor 683,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.6,4,10,-0.2,0.285,0.6,3.08,3.08,0.251,0,0,-0.8,1.7
ENSMUSG00000043190,RFESD,Rieske (Fe-S) domain containing,cellular_component|,biological_process|oxidation-reduction process|,"molecular_function|oxidoreductase activity|metal ion binding|iron-sulfur cluster binding|2 iron, 2 sulfur cluster binding|",10,0,0,10,0.4,3.58,0.4,3.01,3.01,0.257,0,0,-0.2,1.6
ENSMUSG00000023943,SULT1C1,"sulfotransferase family, cytosolic, 1C, member 1",cytoplasm|,sulfur compound metabolic process|metabolic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|alcohol sulfotransferase activity|aryl sulfotransferase activity|aryl sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0.3,1.07,10,0.2,2.26,0.2,2.97,2.97,0.26,0,0,-0.6,1.4
ENSMUSG00000024601,ISOC1,isochorismatase domain containing 1,peroxisome|peroxisome|extracellular vesicular exosome|,biological_process|metabolic process|,molecular_function|catalytic activity|,10,-0.7,1.67,10,-0.2,1.9,-0.3,2.94,-2.94,0.262,0,0,-1.5,1.1
ENSMUSG00000035919,BBS9,Bardet-Biedl syndrome 9 (human),cytoplasm|cytoskeleton|plasma membrane|cilium|membrane|BBSome|BBSome|ciliary basal body|cell projection|,transport|protein transport|cell projection organization|cilium assembly|,protein binding|,10,-0.3,1.82,10,-0.3,1.32,-0.3,2.93,-2.93,0.263,0,0,-1.4,0.8
ENSMUSG00000053205,STYX,serine/threonine/tyrosine interaction protein,nucleus|cytoplasm|cytoplasm|,protein dephosphorylation|spermatogenesis|dephosphorylation|MAPK export from nucleus|regulation of ERK1 and ERK2 cascade|,phosphoprotein phosphatase activity|protein binding|protein tyrosine/serine/threonine phosphatase activity|hydrolase activity|phosphatase activity|,10,-0.5,4.22,10,0,0,-0.5,2.92,-2.92,0.264,0,0,-1.6,0.2
ENSMUSG00000020424,GATSL3,GATS protein-like 3,cellular_component|,biological_process|,molecular_function|,10,0.2,1.58,10,0.3,1.54,0.3,2.91,2.91,0.265,0,0,-0.6,1.4
ENSMUSG00000020867,SPATA20,spermatogenesis associated 20,cellular_component|extracellular region|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,catalytic activity|protein binding|,10,0.2,2.56,10,0.2,0.516,0.2,2.89,2.89,0.266,0,0,-0.5,1.5
ENSMUSG00000022055,NEFL,"neurofilament, light polypeptide",cytoplasm|intermediate filament|neurofilament|neurofilament|axon|axon|growth cone|TSC1-TSC2 complex|neuron projection|neuron projection|neuron projection|,microtubule cytoskeleton organization|anterograde axon cargo transport|retrograde axon cargo transport|peripheral nervous system axon regeneration|axon transport of mitochondrion|regulation of axon diameter|neurofilament bundle assembly|locomotion|negative regulation of neuron apoptotic process|intermediate filament organization|intermediate filament organization|intermediate filament bundle assembly|neuron projection morphogenesis|positive regulation of axonogenesis|neuromuscular process controlling balance|protein polymerization|neurofilament cytoskeleton organization|neurofilament cytoskeleton organization|,"structural molecule activity|structural constituent of cytoskeleton|structural constituent of cytoskeleton|protein binding|protein C-terminus binding|protein domain specific binding|protein binding, bridging|identical protein binding|phospholipase binding|",10,0.3,1.19,10,0.3,1.87,0.3,2.86,2.86,0.269,0,0,-0.4,1.6
ENSMUSG00000004371,IL11,interleukin 11,extracellular region|extracellular space|cytoplasm|,positive regulation of cell proliferation|positive regulation of cell proliferation|positive regulation of peptidyl-serine phosphorylation|positive regulation of MAPK cascade|positive regulation of transcription from RNA polymerase II promoter|negative regulation of hormone secretion|positive regulation of peptidyl-tyrosine phosphorylation|,cytokine activity|interleukin-11 receptor binding|growth factor activity|growth factor activity|,10,0.4,2.48,10,0.4,0.549,0.4,2.85,2.85,0.269,0,0,-1.3,1.4
ENSMUSG00000024939,FAM89B,"family with sequence similarity 89, member B",cytoplasm|,negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of SMAD protein import into nucleus|,transcription corepressor binding|protein binding|,10,0.3,2.2,10,0.2,0.88,0.2,2.85,2.85,0.269,0,0,-0.4,1.4
ENSMUSG00000056708,IER5,immediate early response 5,cellular_component|,biological_process|,molecular_function|,10,0.2,0.746,10,0.4,2.79,0.4,2.82,2.82,0.272,0,0,-0.3,1.6
ENSMUSG00000045795,WHAMM,"WAS protein homolog associated with actin, golgi membranes and microtubules",cytoplasm|Golgi apparatus|membrane|cytoplasmic vesicle|,biological_process|,molecular_function|actin binding|,10,0.4,2.95,10,0.3,0.109,0.4,2.82,2.82,0.272,0,0,-0.5,1.6
ENSMUSG00000003206,EBI3,Epstein-Barr virus induced gene 3,extracellular region|extracellular space|membrane|,cytokine-mediated signaling pathway|,cytokine receptor activity|cytokine activity|protein binding|interleukin-27 receptor binding|,9,0.3,2.12,9,0.2,1.12,0.2,2.8,2.8,0.274,0,0,-0.4,1.6
ENSMUSG00000079235,CCDC13,coiled-coil domain containing 13,cellular_component|,biological_process|,molecular_function|,10,0.3,3.11,10,0.5,0.0683,0.4,2.77,2.77,0.276,0,0,-0.4,1.5
ENSMUSG00000071103,1700029J07RIK,RIKEN cDNA 1700029J07 gene,cellular_component|,biological_process|,molecular_function|,9,-0.1,0.347,9,-0.6,3.6,-0.5,2.72,-2.72,0.281,0,0,-1.8,0.3
ENSMUSG00000034543,MORC2A,microrchidia 2A,nucleus|cytoplasm|,biological_process|,zinc ion binding|metal ion binding|,10,0.3,2.69,10,0.2,0.438,0.3,2.71,2.71,0.282,0,0,-0.6,1.5
ENSMUSG00000034190,CHMP7,charged multivesicular body protein 7,ESCRT III complex|cytoplasm|,transport|protein transport|late endosome to vacuole transport|,protein transporter activity|,10,0.4,0.802,10,0.5,2.17,0.5,2.68,2.68,0.284,0,0,-0.7,1.7
ENSMUSG00000020876,SNX11,sorting nexin 11,endosome|endosome|membrane|,transport|intracellular protein transport|protein transport|vesicle organization|vesicle organization|,lipid binding|phosphatidylinositol binding|phosphatidylinositol phosphate binding|,10,-1,4.25,10,0,0,-0.9,2.66,-2.66,0.286,0,0,-2,0.2
ENSMUSG00000026797,STXBP1,syntaxin binding protein 1,cell|cytoplasm|mitochondrion|plasma membrane|plasma membrane|platelet alpha granule|protein complex|extracellular vesicular exosome|,"platelet degranulation|transport|exocytosis|vesicle docking involved in exocytosis|neurotransmitter secretion|neuromuscular synaptic transmission|axon target recognition|regulation of synaptic vesicle priming|protein transport|synaptic vesicle maturation|vesicle-mediated transport|negative regulation of synaptic transmission, GABAergic|negative regulation of neuron apoptotic process|positive regulation of exocytosis|positive regulation of calcium ion-dependent exocytosis|protein stabilization|long term synaptic depression|platelet aggregation|",SNARE binding|protein binding|syntaxin-1 binding|syntaxin-1 binding|protein kinase binding|protein domain specific binding|syntaxin binding|identical protein binding|poly(A) RNA binding|protein N-terminus binding|,10,-0.2,1.87,10,-0.3,1.03,-0.2,2.64,-2.64,0.288,0,0,-1.5,0.5
ENSMUSG00000022064,PIBF1,progesterone immunomodulatory binding factor 1,centrosome|,biological_process|,molecular_function|,9,0.1,0.452,9,0.5,3.15,0.4,2.64,2.64,0.288,0,0,-0.4,1.7
ENSMUSG00000067889,SPTBN2,"spectrin beta, non-erythrocytic 2",photoreceptor inner segment|extracellular space|plasma membrane|spectrin|apical plasma membrane|neuronal cell body|,synapse assembly|synaptic vesicle exocytosis|vesicle-mediated transport|cerebellar Purkinje cell layer morphogenesis|adult behavior|multicellular organism growth|,actin binding|,10,0,0,10,0.4,4.39,0.3,2.63,2.63,0.289,0,0,-0.4,1.6
ENSMUSG00000068744,PSRC1,proline/serine-rich coiled-coil 1,spindle pole|nucleus|cytoplasm|cytoplasm|spindle|cytosol|cytoskeleton|spindle microtubule|microtubule cytoskeleton|midbody|,"microtubule bundle formation|cell cycle|mitotic nuclear division|mitotic metaphase plate congression|cellular process|negative regulation of cell growth|positive regulation of microtubule polymerization|positive regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of transcription, DNA-templated|cell division|regulation of mitotic spindle organization|",protein binding|microtubule binding|,10,-0.2,0.648,10,0.3,3.78,0.3,2.63,2.63,0.289,0,0,-0.7,1.4
ENSMUSG00000007440,PCDHA2,protocadherin alpha 2,nucleus|endoplasmic reticulum|,biological_process|,molecular_function|,10,0.3,2.11,10,0.2,0.923,0.3,2.59,2.59,0.292,0,0,-0.5,1.5
ENSMUSG00000048720,TBC1D12,"TBC1D12: TBC1 domain family, member 12",cellular_component|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|,10,-0.6,4.97,10,0.3,0.542,-0.5,2.58,-2.58,0.293,0,0,-1.7,0.7
ENSMUSG00000036687,TMEM184A,transmembrane protein 184a,endosome|membrane|integral component of membrane|early endosome membrane|,germ-line sex determination|regulation of protein localization|regulation of secretion|,None,3,0.4,2.93,3,-0.2,0.22,0.4,2.55,2.55,0.296,0,0,-1.1,2
ENSMUSG00000020359,PHYKPL,5-phosphohydroxy-L-lysine phospholyase,mitochondrion|,biological_process|,catalytic activity|transaminase activity|transferase activity|lyase activity|pyridoxal phosphate binding|,10,0.6,2.83,10,0.2,1.2,0.4,2.53,2.53,0.298,0,0,-0.4,1.8
ENSMUSG00000040699,LIMD2,LIM domain containing 2,cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.3,1.76,10,0.2,0.949,0.3,2.51,2.51,0.3,0,0,-0.5,1.5
ENSMUSG00000058503,FAM133B,"family with sequence similarity 133, member B",cellular_component|,biological_process|,poly(A) RNA binding|,10,0.4,0.751,10,0.5,2.03,0.4,2.51,2.51,0.3,0,0,-0.3,1.7
ENSMUSG00000018199,TROVE2,"TROVE domain family, member 2",nucleus|nucleus|cytoplasm|cytoplasm|virion|viral nucleocapsid|ribonucleoprotein complex|ribonucleoprotein complex|,immune system development|smoothened signaling pathway|response to UV|response to UV|cell projection organization|cilium morphogenesis|,RNA binding|RNA binding|U2 snRNA binding|misfolded RNA binding|metal ion binding|,10,-0.2,1.16,10,0.8,5.42,0.7,2.47,2.47,0.303,0,0,-0.4,1.9
ENSMUSG00000035427,MAGEB4,"melanoma antigen, family B, 4",cytoplasm|,biological_process|,molecular_function|,10,0.3,3.17,10,-0.1,0.169,0.2,2.45,2.45,0.305,0,0,-0.8,1.4
ENSMUSG00000027496,AURKA,aurora kinase A,nucleus|cytoplasm|centrosome|centrosome|microtubule organizing center|spindle|cytoskeleton|microtubule|spindle microtubule|microtubule cytoskeleton|spindle pole centrosome|germinal vesicle|axon hillock|pronucleus|perinuclear region of cytoplasm|mitotic spindle|meiotic spindle|,meiotic spindle organization|microtubule cytoskeleton organization|mitotic cell cycle|protein phosphorylation|protein phosphorylation|protein phosphorylation|cell cycle|mitotic spindle organization|spindle assembly involved in female meiosis I|mitotic nuclear division|mitotic centrosome separation|mitotic centrosome separation|meiotic nuclear division|anterior/posterior axis specification|phosphorylation|cell projection organization|regulation of protein stability|negative regulation of protein binding|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|histone-serine phosphorylation|negative regulation of apoptotic process|spindle stabilization|centrosome organization|cell division|centrosome localization|protein localization to centrosome|negative regulation of spindle checkpoint|positive regulation of oocyte maturation|neuron projection extension|,"nucleotide binding|protein kinase activity|protein kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|protein kinase binding|ubiquitin protein ligase binding|histone serine kinase activity|",10,0.3,2.37,10,-0.5,0.809,0.3,2.44,2.44,0.306,0,0,-1.4,1.2
ENSMUSG00000027573,GID8,GID complex subunit 8 homolog (S. cerevisiae),nucleus|cell junction|,biological_process|,molecular_function|,10,0.3,2.79,10,0.1,0.193,0.2,2.42,2.42,0.308,0,0,-0.5,1.5
ENSMUSG00000044968,NAPEPLD,N-acyl phosphatidylethanolamine phospholipase D,membrane|extracellular vesicular exosome|,lipid metabolic process|phospholipid catabolic process|lipid catabolic process|,phospholipase activity|zinc ion binding|hydrolase activity|metal ion binding|N-acylphosphatidylethanolamine-specific phospholipase D activity|,10,-0.2,2.43,10,-0.2,0.137,-0.2,2.42,-2.42,0.308,0,0,-1.5,0.6
ENSMUSG00000032265,FAM46A,"family with sequence similarity 46, member A",cellular_component|,regulation of gene expression|regulation of blood coagulation|,poly(A) RNA binding|,10,0.3,2.69,10,-0.3,1.38,-0.3,2.42,-2.42,0.308,0,0,-1.2,1.1
ENSMUSG00000053080,2700081O15RIK,RIKEN cDNA 2700081O15 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.1,10,-0.9,2.63,-0.4,2.41,-2.41,0.309,0,0,-1.9,0.2
ENSMUSG00000034412,TBC1D10A,"TBC1 domain family, member 10a",cell projection|extracellular vesicular exosome|,regulation of Rab GTPase activity|positive regulation of proteolysis|activation of cysteine-type endopeptidase activity|,guanyl-nucleotide exchange factor activity|GTPase activator activity|Rab GTPase activator activity|PDZ domain binding|,10,0.2,1.34,10,0.2,1.24,0.2,2.4,2.4,0.309,0,0,-0.8,1.4
ENSMUSG00000078861,ZFP931,zinc finger protein 931,blood microparticle|,biological_process|,molecular_function|metal ion binding|,5,0.4,2.81,5,-0.8,1.93,-0.6,2.4,-2.4,0.309,0,0,-2,1.2
ENSMUSG00000040928,S100PBP,S100P binding protein,nucleus|,biological_process|,calcium-dependent protein binding|,10,-1.1,5.12,10,0,0,-0.3,2.38,-2.38,0.311,0,0,-2,0.1
ENSMUSG00000020461,CLHC1,clathrin heavy chain linker domain containing 1,spindle pole|cytoplasm|centrosome|cytoskeleton|,spindle organization|,molecular_function|,10,0.4,4.69,10,-0.2,1.78,0.3,2.37,2.37,0.312,0,0,-0.9,1.3
ENSMUSG00000030876,METTL9,methyltransferase like 9,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,2.71,0.3,2.36,2.36,0.313,0,0,-0.5,1.6
ENSMUSG00000070777,CEACAM20,carcinoembryonic antigen-related cell adhesion molecule 20,cellular_component|,biological_process|,molecular_function|,10,0.8,3.1,10,0.2,0.413,0.3,2.34,2.34,0.315,0,0,-0.2,2
ENSMUSG00000031893,TSNAXIP1,translin-associated factor X (Tsnax) interacting protein 1,cytoplasm|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,protein binding|,10,0.5,4.48,10,-0.2,0.407,0.4,2.34,2.34,0.315,0,0,-0.5,1.7
ENSMUSG00000090394,4930523C07RIK,RIKEN cDNA 4930523C07 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.736,10,0.3,1.91,0.2,2.33,2.33,0.316,0,0,-0.5,1.6
ENSMUSG00000090946,CCDC71L,coiled-coil domain containing 71 like,cellular_component|,biological_process|,molecular_function|,10,0.5,3.01,10,-0.1,0.123,0.5,2.32,2.32,0.317,0,0,-0.8,1.8
ENSMUSG00000024155,MEIOB,meiosis specific with OB domains,nucleus|chromosome|cytoplasm|,"resolution of meiotic recombination intermediates|double-strand break repair via homologous recombination|DNA catabolic process, exonucleolytic|meiotic nuclear division|synapsis|male meiosis I|female meiosis I|fertilization|",DNA binding|chromatin binding|chromatin binding|single-stranded DNA binding|nuclease activity|exonuclease activity|protein binding|single-stranded DNA 3'-5' exodeoxyribonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,0.9,2.66,10,0.2,1.41,0.3,2.31,2.31,0.318,0,0,-0.3,2
ENSMUSG00000024253,DYNC2LI1,dynein cytoplasmic 2 light intermediate chain 1,cytoplasm|cytoskeleton|microtubule|cilium|axoneme|dynein complex|intraciliary transport particle|motile primary cilium|cell projection|apical part of cell|,multicellular organismal development|determination of left/right symmetry|cell projection organization|cilium assembly|,molecular_function|motor activity|,10,0.3,2,10,0.2,0.69,0.3,2.29,2.29,0.32,0,0,-0.6,1.6
ENSMUSG00000043323,FBRSL1,fibrosin-like 1,cellular_component|,biological_process|,poly(A) RNA binding|,10,-0.2,0.779,10,-0.3,1.83,-0.3,2.29,-2.29,0.32,0,0,-1.4,0.9
ENSMUSG00000036667,FAM115A,"family with sequence similarity 115, member A",cellular_component|,biological_process|,molecular_function|,10,0.4,3.03,10,-0.3,0.717,0.3,2.28,2.28,0.321,0,0,-0.9,1.5
ENSMUSG00000062661,NCS1,neuronal calcium sensor 1,cytoplasm|Golgi apparatus|cytosol|plasma membrane|membrane|cell junction|axon|dendrite|dense core granule|cytoplasmic vesicle|intracellular membrane-bounded organelle|synapse|postsynaptic membrane|extracellular vesicular exosome|,regulation of neuron projection development|regulation of ion transmembrane transport|positive regulation of exocytosis|phosphatidylinositol-mediated signaling|positive regulation of synaptic transmission|calcium ion transmembrane transport|,magnesium ion binding|voltage-gated calcium channel activity|calcium ion binding|calcium ion binding|protein kinase binding|metal ion binding|,10,-0.5,2.32,10,-0.2,0.394,-0.4,2.26,-2.26,0.324,0,0,-1.6,0.5
ENSMUSG00000015377,DENND6B,DENN/MADD domain containing 6B,cellular_component|cytoplasm|endosome|,positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,1.1,4.55,10,0.2,0.0806,0.9,2.23,2.23,0.327,0,0,-0.1,2
ENSMUSG00000024970,AI846148,expressed sequence AI846148,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0434,10,-0.4,4.5,-0.4,2.21,-2.21,0.329,0,0,-1.6,0.5
ENSMUSG00000030711,SULT1A1,"sulfotransferase family 1A, phenol-preferring, member 1",cytoplasm|cytosol|,catecholamine metabolic process|lipid metabolic process|xenobiotic metabolic process|steroid metabolic process|estrogen metabolic process|drug metabolic process|4-nitrophenol metabolic process|response to glucocorticoid|sulfation|,nucleotide binding|aryl sulfotransferase activity|sulfotransferase activity|sulfotransferase activity|transferase activity|tyrosine-ester sulfotransferase activity|protein homodimerization activity|3'-phosphoadenosine 5'-phosphosulfate binding|,10,0.6,4.16,10,0.1,0.117,0.3,2.19,2.19,0.331,0,0,-0.8,1.9
ENSMUSG00000027855,SYCP1,synaptonemal complex protein 1,synaptonemal complex|synaptonemal complex|lateral element|central element|transverse filament|male germ cell nucleus|nucleus|chromosome|,meiotic DNA repair synthesis|meiotic DNA repair synthesis|cell cycle|meiotic nuclear division|synaptonemal complex assembly|synaptonemal complex assembly|synaptonemal complex assembly|spermatogenesis|regulation of protein localization|sperm chromatin condensation|chiasma assembly|cell division|lateral element assembly|,DNA binding|protein binding|,10,-1,4.9,10,0,0,-0.4,2.18,-2.18,0.332,0,0,-2,0.2
ENSMUSG00000047153,KHNYN,KH and NYN domain containing,cellular_component|,biological_process|,molecular_function|,10,-0.8,3.04,10,-0.2,0.49,-0.2,2.18,-2.18,0.332,0,0,-1.8,0.4
ENSMUSG00000034121,MKS1,"Meckel syndrome, type 1",cytoplasm|centrosome|centriole|cytoskeleton|cilium|membrane|ciliary transition zone|ciliary transition zone|TCTN-B9D complex|ciliary basal body|cell projection|,cell projection organization|cilium assembly|cilium assembly|branching morphogenesis of an epithelial tube|cilium morphogenesis|,protein binding|,10,0.2,0.676,10,0.8,2.69,0.2,2.17,2.17,0.333,0,0,-0.2,2
ENSMUSG00000041375,CCDC9,coiled-coil domain containing 9,cellular_component|,biological_process|,poly(A) RNA binding|,10,0.2,0.96,10,-0.4,3.29,-0.3,2.16,-2.16,0.334,0,0,-1.5,0.8
ENSMUSG00000037845,FDXACB1,ferredoxin-fold anticodon binding domain containing 1,cellular_component|,phenylalanyl-tRNA aminoacylation|tRNA processing|biological_process|,tRNA binding|magnesium ion binding|molecular_function|phenylalanine-tRNA ligase activity|ATP binding|,10,0.2,0.842,10,0.4,2.07,0.3,2.15,2.15,0.336,0,0,-0.8,1.6
ENSMUSG00000064280,CCDC146,coiled-coil domain containing 146,cellular_component|,biological_process|,molecular_function|,10,0.3,0.825,10,0.4,1.48,0.3,2.13,2.13,0.338,0,0,-0.4,1.7
ENSMUSG00000032431,CRTAP,cartilage associated protein,extracellular region|proteinaceous extracellular matrix|extracellular space|endoplasmic reticulum|endoplasmic reticulum|,peptidyl-proline hydroxylation to 3-hydroxy-L-proline|protein stabilization|negative regulation of post-translational protein modification|,None,10,0.4,1.82,10,0.3,0.523,0.3,2.13,2.13,0.338,0,0,-0.4,1.7
ENSMUSG00000039637,CORO7,coronin 7,cytoplasm|Golgi apparatus|trans-Golgi network|membrane|membrane|integral component of membrane|cytoplasmic vesicle|,transport|biological_process|protein transport|,actin binding|actin binding|,10,0.4,3.87,10,0,0,0.3,2.13,2.13,0.338,0,0,-0.7,1.6
ENSMUSG00000028669,PITHD1,PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1,nucleus|,biological_process|,molecular_function|,10,-0.7,4.79,10,0.5,0.0936,-0.6,2.11,-2.11,0.34,0,0,-1.8,0.9
ENSMUSG00000042340,CTF1,cardiotrophin 1,extracellular region|extracellular space|,nervous system development|neuron development|leukemia inhibitory factor signaling pathway|,cytokine activity|leukemia inhibitory factor receptor binding|,9,-0.4,4.38,9,0.5,2,-0.4,2.1,-2.1,0.341,0,0,-1.3,1.4
ENSMUSG00000038028,9630033F20RIK,RIKEN cDNA 9630033F20 gene,intracellular|,metabolic process|response to xenobiotic stimulus|response to gamma radiation|positive regulation of cardiac muscle cell apoptotic process|intestinal epithelial cell development|negative regulation of macromitophagy|negative regulation of reactive oxygen species metabolic process|,"molecular_function|catalytic activity|fructose-2,6-bisphosphate 2-phosphatase activity|hydrolase activity|",10,-0.6,3.14,10,-0.2,0.539,-0.3,2.08,-2.08,0.343,0,0,-1.6,0.9
ENSMUSG00000051728,4930563D23RIK,RIKEN cDNA 4930563D23 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,2.81,10,0.1,0.449,0.4,2.08,2.08,0.343,0,0,-0.6,1.8
ENSMUSG00000040025,YTHDF2,YTH domain family 2,cytoplasmic mRNA processing body|cytoplasm|,regulation of mRNA stability|,RNA binding|poly(A) RNA binding|N6-methyladenosine-containing RNA binding|,10,0.3,4.15,10,-0.2,0.432,0.2,2.08,2.08,0.343,0,0,-0.9,1.4
ENSMUSG00000028468,RGP1,RGP1 retrograde golgi transport homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0.4,3.4,9,0,0,0.3,2.07,2.07,0.344,0,0,-1.2,1.4
ENSMUSG00000019988,NEDD1,"neural precursor cell expressed, developmentally down-regulated gene 1","pericentriolar material|spindle pole|gamma-tubulin ring complex, centrosomal|cytoplasm|centrosome|centrosome|centriole|cytoskeleton|ciliary basal body|apical part of cell|",microtubule depolymerization|cell cycle|mitotic nuclear division|microtubule polymerization or depolymerization|cell division|regulation of establishment of protein localization|,None,10,-0.1,0.135,10,0.3,2.66,-0.6,2.01,-2.01,0.351,0,0,-1.7,0.9
ENSMUSG00000029823,LUC7L2,LUC7-like 2 (S. cerevisiae),nucleus|U1 snRNP|,mRNA splice site selection|,mRNA binding|enzyme binding|poly(A) RNA binding|,10,-0.3,2.92,10,0,0,-0.2,2.01,-2.01,0.351,0,0,-1.5,0.7
ENSMUSG00000029276,GLMN,"glomulin, FKBP associated protein",cullin-RING ubiquitin ligase complex|Cul2-RING ubiquitin ligase complex|Cul3-RING ubiquitin ligase complex|Cul4A-RING E3 ubiquitin ligase complex|,"vasculogenesis|neural tube closure|cell surface receptor signaling pathway|negative regulation of cell proliferation|negative regulation of protein ubiquitination|regulation of proteasomal ubiquitin-dependent protein catabolic process|regulation of gene expression, epigenetic|negative regulation of T cell proliferation|positive regulation of phosphorylation|muscle cell differentiation|negative regulation of catalytic activity|positive regulation of interleukin-2 biosynthetic process|positive regulation of cytokine secretion|circulatory system development|",receptor binding|hepatocyte growth factor receptor binding|protein binding|ubiquitin protein ligase binding|ubiquitin-protein transferase inhibitor activity|,10,0.3,2.25,10,0.6,0.669,0.2,2.01,2.01,0.351,0,0,-0.9,1.7
ENSMUSG00000003418,ST8SIA6,"ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6",Golgi apparatus|membrane|integral component of membrane|integral component of Golgi membrane|,ganglioside biosynthetic process|protein glycosylation|protein O-linked glycosylation|glycoprotein metabolic process|glycolipid biosynthetic process|oligosaccharide metabolic process|carbohydrate biosynthetic process|sialylation|,"sialyltransferase activity|lytic endotransglycosylase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.407,10,0.3,2.07,0.3,1.98,1.98,0.354,0,0,-0.5,1.7
ENSMUSG00000025898,CWF19L2,"CWF19-like 2, cell cycle control (S. pombe)",cellular_component|,biological_process|,molecular_function|catalytic activity|,10,-0.4,1.78,10,0.2,1.17,-0.3,1.96,-1.96,0.357,0,0,-1.4,1
ENSMUSG00000042729,WDR74,WD repeat domain 74,nucleus|nucleus|nucleolus|,blastocyst formation|RNA metabolic process|,molecular_function|,8,0.2,0.369,8,0.9,3.31,0.7,1.95,1.95,0.358,0,0,-1.6,2
ENSMUSG00000023904,HCFC1R1,host cell factor C1 regulator 1 (XPO1-dependent),cellular_component|nucleus|cytoplasm|,biological_process|,molecular_function|,9,0.1,0.405,9,0.2,1.83,0.2,1.94,1.94,0.359,0,0,-1.3,1.5
ENSMUSG00000040520,MANEA,"mannosidase, endo-alpha",Golgi apparatus|membrane|integral component of membrane|,metabolic process|,"alpha-mannosidase activity|glycoprotein endo-alpha-1,2-mannosidase activity|hydrolase activity|",10,-0.4,2.47,10,0,0,-0.4,1.91,-1.91,0.362,0,0,-1.6,0.8
ENSMUSG00000004865,SRPK1,serine/arginine-rich protein specific kinase 1,intracellular|nucleus|cytoplasm|endoplasmic reticulum|plasma membrane|intracellular membrane-bounded organelle|,mRNA processing|protein phosphorylation|protein phosphorylation|chromosome segregation|RNA splicing|phosphorylation|cell differentiation|intracellular signal transduction|intracellular signal transduction|positive regulation of viral genome replication|negative regulation of viral genome replication|regulation of mRNA processing|regulation of mRNA processing|,"nucleotide binding|magnesium ion binding|magnesium ion binding|protein kinase activity|protein serine/threonine kinase activity|protein serine/threonine kinase activity|protein binding|ATP binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|poly(A) RNA binding|",9,0.5,3.81,9,-0.4,0.785,0.4,1.91,1.91,0.362,0,0,-1.1,1.7
ENSMUSG00000050876,SPATA31D1A,"spermatogenesis associated 31 subfamily D, member 1A",cellular_component|,biological_process|,molecular_function|,10,0.1,0.0485,10,0.3,2.71,0.3,1.91,1.91,0.362,0,0,-0.6,1.7
ENSMUSG00000035236,SCAI,suppressor of cancer cell invasion,nucleus|cytoplasm|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|negative regulation of signal transduction|negative regulation of cell migration|negative regulation of cell migration|negative regulation of Rho protein signal transduction|regulation of RNA biosynthetic process|",transcription corepressor activity|transcription corepressor activity|protein binding|,10,0.2,0.507,10,0.2,1.53,0.2,1.9,1.9,0.364,0,0,-0.9,1.5
ENSMUSG00000036661,DENND3,DENN/MADD domain containing 3,intracellular|cell|,endosome to lysosome transport|positive regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|cellular protein catabolic process|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,0.4,3.61,10,0,0,0.3,1.86,1.86,0.368,0,0,-0.6,1.7
ENSMUSG00000073755,5730409E04RIK,RIKEN cDNA 5730409E04Rik gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,3.08,0.2,1.85,1.85,0.369,0,0,-0.8,1.6
ENSMUSG00000066571,4931406P16RIK,RIKEN cDNA 4931406P16 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,3.01,10,0,0,0.2,1.85,1.85,0.369,0,0,-0.6,1.6
ENSMUSG00000007379,DENND2C,DENN/MADD domain containing 2C,cellular_component|,positive regulation of Rab GTPase activity|,guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|,10,-0.2,0.858,10,-0.2,1.14,-0.2,1.85,-1.85,0.369,0,0,-1.6,0.7
ENSMUSG00000026315,SERPINB8,"serine (or cysteine) peptidase inhibitor, clade B, member 8",extracellular space|cytoplasm|cytosol|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.4,3.92,10,-0.3,1.36,0.3,1.83,1.83,0.372,0,0,-0.9,1.5
ENSMUSG00000066108,MUC5B,"mucin 5, subtype B, tracheobronchial",extracellular region|extracellular space|,biological_process|,molecular_function|,10,0.4,3.14,10,1.3,1.83,0.5,1.81,1.81,0.375,0,0,-0.1,2
ENSMUSG00000064080,FBLN2,fibulin 2,extracellular region|proteinaceous extracellular matrix|extracellular vesicular exosome|,positive regulation of cell-substrate adhesion|,calcium ion binding|protein binding|extracellular matrix binding|,10,0.3,1.77,10,0.2,0.218,0.2,1.81,1.81,0.375,0,0,-0.9,1.5
ENSMUSG00000071202,CCDC78,coiled-coil domain containing 78,cytoplasm|centriole|cytoskeleton|plasma membrane|membrane|sarcoplasmic reticulum|sarcolemma|perinuclear region of cytoplasm|deuterosome|,skeletal muscle contraction|cell projection organization|de novo centriole assembly|,molecular_function|,9,0.9,2.01,9,0.5,0.507,0.7,1.8,1.8,0.376,0,0,-0.4,2
ENSMUSG00000048327,CKAP2L,cytoskeleton associated protein 2-like,cytoplasm|centrosome|cytoskeleton|,biological_process|,molecular_function|,10,-0.3,1.21,10,-0.3,0.733,-0.3,1.8,-1.8,0.376,0,0,-1.7,0.4
ENSMUSG00000074182,ZNHIT6,"zinc finger, HIT type 6",extracellular vesicular exosome|pre-snoRNP complex|,box C/D snoRNP assembly|ribosome biogenesis|,enzyme binding|identical protein binding|metal ion binding|,10,0.3,1.49,10,0.3,0.432,0.3,1.79,1.79,0.377,0,0,-0.5,1.7
ENSMUSG00000037499,NENF,neuron derived neurotrophic factor,extracellular region|extracellular space|,positive regulation of MAPK cascade|,growth factor activity|heme binding|metal ion binding|,10,0,0,10,0.3,3.31,0.2,1.79,1.79,0.377,0,0,-0.7,1.6
ENSMUSG00000075271,TTC30A1,tetratricopeptide repeat domain 30A1,intracellular|cell|centrosome|cilium|cilium|intraciliary transport particle B|intraciliary transport particle B|cell projection|,cell projection organization|intraciliary anterograde transport|intraciliary transport|cilium assembly|,molecular_function|,10,0,0,10,-0.6,3.56,-0.5,1.78,-1.78,0.378,0,0,-1.9,0.2
ENSMUSG00000073616,MYEOV2,myeloma overexpressed 2,cellular_component|,biological_process|,molecular_function|,10,-0.4,2,10,-0.2,0.143,-0.3,1.78,-1.78,0.378,0,0,-1.5,1
ENSMUSG00000042988,NOTUM,notum pectinacetylesterase homolog (Drosophila),cellular_component|extracellular region|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0.1,0.0972,10,0.9,3.39,0.2,1.77,1.77,0.38,0,0,-0.6,2
ENSMUSG00000040177,2310057M21RIK,RIKEN cDNA 2310057M21 gene,cellular_component|,biological_process|,identical protein binding|,10,0.1,0.628,10,0.2,1.34,0.2,1.77,1.77,0.38,0,0,-0.8,1.6
ENSMUSG00000025377,ENTHD2,ENTH domain containing 2,cellular_component|cytoplasm|cytoplasmic vesicle|,biological_process|,molecular_function|,10,0,0,10,0.2,2.26,0.2,1.76,1.76,0.381,0,0,-0.7,1.6
ENSMUSG00000068747,SORT1,sortilin 1,nucleus|lysosome|endosome|early endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|coated pit|cell surface|membrane|integral component of membrane|cytoplasmic membrane-bounded vesicle|clathrin-coated vesicle|trans-Golgi network transport vesicle|dendrite|neuronal cell body|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|,ossification|transport|Golgi to endosome transport|endocytosis|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|multicellular organismal development|endosome to lysosome transport|extrinsic apoptotic signaling pathway via death domain receptors|regulation of gene expression|myotube differentiation|myotube differentiation|vesicle organization|vesicle organization|cell differentiation|endosome transport via multivesicular body sorting pathway|response to insulin|response to insulin|nerve growth factor signaling pathway|glucose import|glucose import|neurotrophin TRK receptor signaling pathway|plasma membrane to endosome transport|negative regulation of lipoprotein lipase activity|,"protein binding|nerve growth factor receptor activity|enzyme binding|neurotensin receptor activity, non-G-protein coupled|nerve growth factor binding|",10,-0.3,1.46,10,-0.1,0.507,-0.2,1.76,-1.76,0.381,0,0,-1.7,0.7
ENSMUSG00000028300,3110043O21RIK,RIKEN cDNA 3110043O21 gene,extracellular region|extracellular space|extracellular space|nucleus|nucleus|cytoplasm|lysosome|endosome|autophagic vacuole|cytoplasmic vesicle|,endocytosis|autophagy|,protein binding|Rab GTPase binding|Rab GTPase binding|,10,0.2,1.62,10,0.3,0.297,0.2,1.76,1.76,0.381,0,0,-1.5,1.3
ENSMUSG00000025889,SNCA,"synuclein, alpha",cell|nucleus|nucleus|nuclear outer membrane|cytoplasm|cytoplasm|mitochondrion|mitochondrion|rough endoplasmic reticulum|Golgi apparatus|cytosol|cytosol|ribosome|cytoskeleton|plasma membrane|plasma membrane|cell cortex|synaptic vesicle|actin cytoskeleton|inclusion body|inclusion body|axon|growth cone|cytoplasmic vesicle membrane|platelet alpha granule membrane|terminal bouton|fibril|intracellular membrane-bounded organelle|axon terminus|synapse|perinuclear region of cytoplasm|,"microglial cell activation|positive regulation of receptor recycling|negative regulation of protein phosphorylation|positive regulation of neurotransmitter secretion|synaptic transmission, dopaminergic|fatty acid metabolic process|neutral lipid metabolic process|phospholipid metabolic process|activation of cysteine-type endopeptidase activity involved in apoptotic process|mitochondrial membrane organization|synaptic transmission|adult locomotory behavior|response to iron(II) ion|regulation of phospholipase activity|negative regulation of platelet-derived growth factor receptor signaling pathway|regulation of glutamate secretion|regulation of dopamine secretion|negative regulation of microtubule polymerization|receptor internalization|protein destabilization|response to magnesium ion|negative regulation of transporter activity|response to lipopolysaccharide|negative regulation of monooxygenase activity|positive regulation of peptidyl-serine phosphorylation|response to interferon-gamma|cellular response to oxidative stress|negative regulation of histone acetylation|regulation of locomotion|dopamine biosynthetic process|dopamine metabolic process|response to drug|mitochondrial ATP synthesis coupled electron transport|regulation of macrophage activation|negative regulation of apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of endocytosis|negative regulation of exocytosis|negative regulation of dopamine metabolic process|regulation of neurotransmitter secretion|regulation of neurotransmitter secretion|behavioral response to cocaine|regulation of neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|synaptic vesicle endocytosis|synaptic vesicle transport|positive regulation of synaptic transmission|synapse organization|regulation of acyl-CoA biosynthetic process|regulation of acyl-CoA biosynthetic process|positive regulation of release of sequestered calcium ion into cytosol|negative regulation of dopamine uptake involved in synaptic transmission|negative regulation of serotonin uptake|negative regulation of norepinephrine uptake|oxidation-reduction process|regulation of excitatory postsynaptic membrane potential|long-term synaptic potentiation|positive regulation of inositol phosphate biosynthetic process|membrane organization|negative regulation of thrombin receptor signaling pathway|response to interleukin-1|cellular response to copper ion|positive regulation of protein serine/threonine kinase activity|regulation of neuron death|",magnesium ion binding|copper ion binding|calcium ion binding|protein binding|phospholipid binding|microtubule binding|ferrous iron binding|zinc ion binding|oxidoreductase activity|kinesin binding|enzyme binding|protein domain specific binding|Hsp70 protein binding|histone binding|histone binding|identical protein binding|identical protein binding|alpha-tubulin binding|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|phospholipase binding|dynein binding|metal ion binding|protein N-terminus binding|tau protein binding|beta-tubulin binding|arachidonic acid binding|phosphoprotein binding|,10,0.6,2.89,10,-0.2,0.505,0.5,1.75,1.75,0.383,0,0,-0.6,1.8
ENSMUSG00000050668,GPATCH11,G patch domain containing 11,cellular_component|,biological_process|,molecular_function|nucleic acid binding|,10,-0.1,0.388,10,-0.4,2.15,-0.3,1.75,-1.75,0.383,0,0,-1.6,0.6
ENSMUSG00000022787,WDR53,WD repeat domain 53,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,2.45,0.3,1.71,1.71,0.388,0,0,-0.8,1.6
ENSMUSG00000040649,RIMKLB,ribosomal modification protein rimK-like family member B,cytoplasm|,cellular protein modification process|,nucleotide binding|catalytic activity|ATP binding|ligase activity|metal ion binding|N-acetyl-L-aspartate-L-glutamate ligase activity|citrate-L-glutamate ligase activity|,10,-0.6,3.12,10,0,0,-0.5,1.71,-1.71,0.388,0,0,-1.8,0.4
ENSMUSG00000045932,IFIT2,interferon-induced protein with tetratricopeptide repeats 2,cytoplasm|endoplasmic reticulum|,immune system process|apoptotic process|response to virus|response to virus|negative regulation of protein binding|cellular response to interferon-alpha|positive regulation of apoptotic process|innate immune response|defense response to virus|,RNA binding|poly(A) RNA binding|,10,0.1,0.115,10,0.3,2.52,0.3,1.7,1.7,0.389,0,0,-0.6,1.7
ENSMUSG00000028784,SPOCD1,SPOC domain containing 1,cellular_component|,negative regulation of phosphatase activity|,molecular_function|,10,0.2,0.664,10,0.3,1.43,0.3,1.7,1.7,0.389,0,0,-0.6,1.7
ENSMUSG00000025262,FAM120C,"family with sequence similarity 120, member C",cellular_component|,biological_process|,poly(A) RNA binding|,10,0.3,2.95,10,0,0,0.2,1.69,1.69,0.391,0,0,-0.8,1.6
ENSMUSG00000006526,TMEM110,transmembrane protein 110,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,2.35,10,0,0,-0.2,1.67,-1.67,0.393,0,0,-1.4,1.3
ENSMUSG00000024251,THADA,thyroid adenoma associated,cellular_component|,biological_process|,molecular_function|,10,0.2,1.82,10,0.1,0.292,0.2,1.66,1.66,0.394,0,0,-0.9,1.5
ENSMUSG00000022748,CMSS1,cms small ribosomal subunit 1,cellular_component|,biological_process|,poly(A) RNA binding|,10,-0.2,1.18,10,-0.3,0.647,-0.2,1.61,-1.61,0.401,0,0,-1.6,0.8
ENSMUSG00000038524,FCHSD1,FCH and double SH3 domains 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.469,10,-0.7,2.31,-0.2,1.61,-1.61,0.401,0,0,-1.9,0.5
ENSMUSG00000041141,PNMAL1,PNMA-like 1,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.33,10,-0.1,0.408,-0.2,1.59,-1.59,0.404,0,0,-1.8,0.5
ENSMUSG00000001039,B9D1,B9 protein domain 1,cytoplasm|centrosome|cytoskeleton|cilium|membrane|ciliary transition zone|TCTN-B9D complex|ciliary basal body|cell projection|,in utero embryonic development|vasculature development|smoothened signaling pathway|cell projection organization|regulation of protein localization|cilium assembly|embryonic digit morphogenesis|camera-type eye development|cilium morphogenesis|neuroepithelial cell differentiation|,protein binding|hedgehog receptor activity|,10,0.4,1.97,10,0.2,0.27,0.3,1.56,1.56,0.408,0,0,-0.7,1.8
ENSMUSG00000037656,SLC20A2,"solute carrier family 20, member 2",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|phosphate ion transport|viral process|,inorganic phosphate transmembrane transporter activity|symporter activity|,10,0.3,0.907,10,0.2,1.08,0.2,1.56,1.56,0.408,0,0,-0.7,1.7
ENSMUSG00000043542,ZC2HC1A,"zinc finger, C2HC-type containing 1A",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,-0.6,3.14,-0.3,1.54,-1.54,0.411,0,0,-1.8,0.6
ENSMUSG00000068860,GM128,predicted gene 128,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.1,0.306,10,-0.3,2,-0.2,1.54,-1.54,0.411,0,0,-1.6,0.8
ENSMUSG00000021411,PXDC1,PX domain containing 1,cellular_component|,biological_process|,molecular_function|phosphatidylinositol binding|,10,0.2,0.734,10,0.2,0.919,0.2,1.53,1.53,0.413,0,0,-1.2,1.4
ENSMUSG00000040389,WDR47,WD repeat domain 47,cellular_component|cytoplasm|cytoskeleton|microtubule|,multicellular organismal development|biological_process|,molecular_function|,10,0.4,2.05,10,0.7,0.499,0.6,1.53,1.53,0.413,0,0,-0.6,1.8
ENSMUSG00000031669,GINS3,GINS complex subunit 3 (Psf3 homolog),nucleus|,DNA replication|,molecular_function|,10,0.2,0.157,10,0.5,2.25,0.4,1.53,1.53,0.413,0,0,-1,1.7
ENSMUSG00000033967,2310014L17RIK,RIKEN cDNA 2310014L17 gene,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.4,3.56,10,0,0,0.3,1.53,1.53,0.413,0,0,-0.6,1.7
ENSMUSG00000020315,SPTBN1,"spectrin beta, non-erythrocytic 1",intracellular|cell|nucleus|nucleolus|cytoplasm|cytoskeleton|plasma membrane|spectrin|membrane|axolemma|cortical cytoskeleton|M band|cuticular plate|protein complex|extracellular vesicular exosome|,mitotic cytokinesis|plasma membrane organization|common-partner SMAD protein phosphorylation|SMAD protein import into nucleus|Golgi to plasma membrane protein transport|actin filament capping|membrane assembly|protein targeting to plasma membrane|protein targeting to plasma membrane|,actin binding|structural constituent of cytoskeleton|protein binding|calmodulin binding|phospholipid binding|ankyrin binding|protein complex binding|poly(A) RNA binding|,10,-0.3,1.33,10,0.2,0.644,-0.3,1.5,-1.5,0.417,0,0,-1.5,0.9
ENSMUSG00000021286,ZFYVE21,"zinc finger, FYVE domain containing 21",cellular_component|endosome|cell junction|cytoplasmic vesicle|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0.3,1.95,0.3,1.49,1.49,0.419,0,0,-1,1.5
ENSMUSG00000042485,MUSTN1,"musculoskeletal, embryonic nuclear protein 1",nucleus|nucleoplasm|,wound healing|tissue regeneration|,molecular_function|,10,0.7,4.06,10,0,0,0.2,1.49,1.49,0.419,0,0,-0.3,1.9
ENSMUSG00000009108,GNAT2,"guanine nucleotide binding protein, alpha transducing 2",photoreceptor outer segment|photoreceptor outer segment|photoreceptor inner segment|photoreceptor inner segment|heterotrimeric G-protein complex|heterotrimeric G-protein complex|membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|GTP catabolic process|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger|positive regulation of cytosolic calcium ion concentration|visual perception|visual perception|phototransduction|phototransduction|detection of visible light|response to light intensity|retinal cone cell development|response to stimulus|detection of light stimulus involved in visual perception|detection of light stimulus involved in visual perception|,nucleotide binding|G-protein coupled receptor binding|GTPase activity|GTPase activity|signal transducer activity|GTP binding|G-protein coupled photoreceptor activity|guanyl nucleotide binding|G-protein beta/gamma-subunit complex binding|metal ion binding|,10,0.8,2.45,10,0.2,0.299,0.2,1.48,1.48,0.421,0,0,-0.5,1.9
ENSMUSG00000054676,1600014C10RIK,RIKEN cDNA 1600014C10 gene,mitochondrion|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.885,10,-0.3,0.835,-0.2,1.47,-1.47,0.422,0,0,-1.4,1.6
ENSMUSG00000024831,IGHMBP2,immunoglobulin mu binding protein 2,nucleus|nucleus|cytoplasm|cytoplasm|membrane|axon|growth cone|ribonucleoprotein complex|cell projection|neuronal cell body|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|ATP catabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|translation|spinal cord motor neuron differentiation|DNA duplex unwinding|protein homooligomerization|",tRNA binding|nucleotide binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|nucleic acid binding|DNA binding|RNA binding|helicase activity|ATP binding|DNA-dependent ATPase activity|transcription factor binding|RNA-dependent ATPase activity|zinc ion binding|hydrolase activity|ATP-dependent 5'-3' RNA helicase activity|ribosome binding|ribosome binding|ATP-dependent 5'-3' DNA helicase activity|metal ion binding|,10,0,0,10,-0.3,2.16,-0.2,1.46,-1.46,0.424,0,0,-1.6,0.8
ENSMUSG00000038375,TRP53INP2,transformation related protein 53 inducible nuclear protein 2,nucleus|cytoplasm|autophagic vacuole|cytosol|cytoplasmic vesicle|,"autophagic vacuole assembly|osteoblast differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|autophagy|positive regulation of autophagy|positive regulation of transcription, DNA-templated|",molecular_function|,10,0.2,0.855,9,0.2,0.709,0.2,1.44,1.44,0.427,0,0,-1.1,1.6
ENSMUSG00000026601,AXDND1,axonemal dynein light chain domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.6,2.75,-0.5,1.44,-1.44,0.427,0,0,-1.9,0.5
ENSMUSG00000049504,PROSER1,proline and serine rich 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.234,10,0.3,1.65,0.2,1.43,1.43,0.428,0,0,-1.1,1.5
ENSMUSG00000072620,SLFN2,schlafen 2,None,negative regulation of cell proliferation|,None,10,-0.2,0.557,10,-0.3,1.14,-0.2,1.42,-1.42,0.43,0,0,-1.7,0.7
ENSMUSG00000039452,SNX22,sorting nexin 22,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.243,10,0.4,3.17,0.3,1.41,1.41,0.431,0,0,-0.8,1.7
ENSMUSG00000035228,CCDC106,coiled-coil domain containing 106,nucleus|cytoplasm|,biological_process|,molecular_function|,10,-0.2,0.683,10,-0.2,0.844,-0.2,1.41,-1.41,0.431,0,0,-1.6,0.9
ENSMUSG00000062822,4833420G17RIK,RIKEN cDNA 4833420G17 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.8,1.87,0.7,1.4,1.4,0.433,0,0,-0.3,2
ENSMUSG00000030663,1110004F10RIK,RIKEN cDNA 1110004F10 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.474,10,0.3,1.23,0.2,1.4,1.4,0.433,0,0,-1,1.6
ENSMUSG00000035062,ZC4H2,"zinc finger, C4H2 domain containing",nucleus|cytoplasm|plasma membrane|membrane|cell junction|synapse|postsynaptic membrane|,multicellular organismal development|nervous system development|,molecular_function|metal ion binding|,10,0.3,0.88,10,0.2,0.645,0.3,1.39,1.39,0.435,0,0,-1.4,1.3
ENSMUSG00000031574,STAR,steroidogenic acute regulatory protein,mitochondrion|mitochondrial intermembrane space|cytosol|mitochondrial crista|neuron projection|neuronal cell body|,steroid biosynthetic process|bile acid biosynthetic process|estrogen biosynthetic process|transport|lipid transport|glucocorticoid metabolic process|positive regulation of gene expression|cellular response to interferon-alpha|negative regulation of neuron apoptotic process|cellular lipid metabolic process|regulation of neuronal synaptic plasticity|positive regulation of neurogenesis|regulation of steroid biosynthetic process|,lipid binding|,10,-0.4,2.28,10,0,0,-0.2,1.37,-1.37,0.438,0,0,-1.7,0.7
ENSMUSG00000072941,SOD3,"superoxide dismutase 3, extracellular",extracellular region|extracellular space|extracellular space|nucleus|cytoplasm|cytoplasm|trans-Golgi network|extracellular matrix|extracellular matrix|extracellular matrix|extracellular vesicular exosome|,response to hypoxia|superoxide metabolic process|removal of superoxide radicals|removal of superoxide radicals|response to copper ion|oxidation-reduction process|,superoxide dismutase activity|superoxide dismutase activity|copper ion binding|protein binding|zinc ion binding|antioxidant activity|oxidoreductase activity|metal ion binding|,10,0.5,2.4,10,0.1,0.45,0.4,1.37,1.37,0.438,0,0,-0.7,1.8
ENSMUSG00000032712,2810474O19RIK,RIKEN cDNA 2810474O19 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,1.09,10,0.1,0.54,0.2,1.37,1.37,0.438,0,0,-0.8,1.7
ENSMUSG00000018566,SLC2A4,"solute carrier family 2 (facilitated glucose transporter), member 4",cytoplasm|endosome|endosome|multivesicular body|plasma membrane|plasma membrane|integral component of plasma membrane|coated pit|external side of plasma membrane|cell surface|endomembrane system|vesicle membrane|membrane|membrane|integral component of membrane|clathrin-coated vesicle|trans-Golgi network transport vesicle|T-tubule|cytoplasmic vesicle membrane|cytoplasmic vesicle membrane|vesicle|insulin-responsive compartment|insulin-responsive compartment|sarcolemma|sarcolemma|intracellular membrane-bounded organelle|perinuclear region of cytoplasm|perinuclear region of cytoplasm|extracellular vesicular exosome|,transport|carbohydrate transport|amylopectin biosynthetic process|glucose transport|glucose transport|glucose transport|proton transport|cellular response to insulin stimulus|cellular response to insulin stimulus|ion transmembrane transport|hexose transmembrane transport|glucose homeostasis|brown fat cell differentiation|transmembrane transport|cellular response to hypoxia|cellular response to osmotic stress|,transporter activity|glucose transmembrane transporter activity|glucose transmembrane transporter activity|glucose transmembrane transporter activity|insulin-responsive hydrogen:glucose symporter activity|protein binding|transmembrane transporter activity|substrate-specific transmembrane transporter activity|D-glucose transmembrane transporter activity|,10,0.1,0.511,10,0.4,1.65,0.3,1.37,1.37,0.438,0,0,-1.1,1.6
ENSMUSG00000022816,FSTL1,follistatin-like 1,extracellular region|extracellular space|,response to starvation|,calcium ion binding|protein binding|heparin binding|,10,0,0,10,-0.3,2.94,-0.3,1.37,-1.37,0.438,0,0,-1.7,0.7
ENSMUSG00000032065,TEX12,testis expressed gene 12,synaptonemal complex|synaptonemal complex|central element|,meiotic DNA repair synthesis|meiotic DNA repair synthesis|synaptonemal complex assembly|synaptonemal complex assembly|,protein binding|,7,-1,3.37,7,0.1,0.312,-0.9,1.37,-1.37,0.438,0,0,-2,0.7
ENSMUSG00000044551,9930012K11RIK,RIKEN cDNA 9930012K11 gene,None,biological_process|,molecular_function|,10,0.7,2.87,10,0,0,0.2,1.36,1.36,0.44,0,0,-0.4,2
ENSMUSG00000050592,FAM78A,"family with sequence similarity 78, member A",cellular_component|,biological_process|,molecular_function|,10,0.7,1.53,10,0.3,0.74,0.3,1.35,1.35,0.441,0,0,-0.4,1.9
ENSMUSG00000042271,NXT2,nuclear transport factor 2-like export factor 2,cellular_component|intracellular|nucleus|cytoplasm|,transport|biological_process|protein transport|mRNA transport|,protein binding|,10,0.3,1.38,10,0.1,0.62,0.2,1.35,1.35,0.441,0,0,-0.7,1.7
ENSMUSG00000001518,ITFG2,integrin alpha FG-GAP repeat containing 2,nucleoplasm|cytosol|,germinal center B cell differentiation|,molecular_function|,10,0.1,0.227,10,-0.6,2.36,-0.2,1.34,-1.34,0.443,0,0,-1.9,0.5
ENSMUSG00000003435,SUPT5,suppressor of Ty 5,nucleus|DSIF complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|DNA-templated transcription, elongation|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription elongation from RNA polymerase II promoter|positive regulation of macroautophagy|regulation of DNA-templated transcription, elongation|negative regulation of DNA-templated transcription, elongation|positive regulation of DNA-templated transcription, elongation|positive regulation of transcription from RNA polymerase II promoter|",chromatin binding|enzyme binding|poly(A) RNA binding|protein heterodimerization activity|,9,-0.1,0.451,9,-0.2,1.06,-0.2,1.34,-1.34,0.443,0,0,-1.3,1.7
ENSMUSG00000038323,1700066M21RIK,RIKEN cDNA 1700066M21 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.3,0.992,10,0.6,3.62,-0.4,1.34,-1.34,0.443,0,0,-1.2,1.6
ENSMUSG00000062014,GMFB,"glia maturation factor, beta",intracellular|,learning|locomotory behavior|,actin binding|growth factor activity|,10,0.2,2.08,10,0,0,0.2,1.32,1.32,0.446,0,0,-0.9,1.6
ENSMUSG00000030814,BCL7C,B cell CLL/lymphoma 7C,cellular_component|,apoptotic process|biological_process|,molecular_function|,10,0.1,0.397,10,0.3,1.61,0.2,1.31,1.31,0.447,0,0,-0.8,1.7
ENSMUSG00000055069,RAB39,"RAB39, member RAS oncogene family",plasma membrane|membrane|cytoplasmic vesicle|phagocytic vesicle|,transport|small GTPase mediated signal transduction|protein transport|phagosome acidification|phagosome-lysosome fusion|,nucleotide binding|GTP binding|,10,0.3,3,10,0,0,0.2,1.29,1.29,0.451,0,0,-1.2,1.5
ENSMUSG00000067006,SERPINB5,"serine (or cysteine) peptidase inhibitor, clade B, member 5",extracellular region|extracellular space|cytoplasm|cytoplasm|extracellular vesicular exosome|,morphogenesis of an epithelium|negative regulation of endopeptidase activity|regulation of proteolysis|extracellular matrix organization|regulation of epithelial cell proliferation|prostate gland morphogenesis|,serine-type endopeptidase inhibitor activity|,10,0,0,10,0.8,2.96,0.2,1.29,1.29,0.451,0,0,-0.3,2
ENSMUSG00000030034,INO80B,INO80 complex subunit B,nucleus|cytoplasm|plasma membrane|Ino80 complex|,"DNA repair|DNA recombination|transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|biological_process|",protein binding|metal ion binding|,10,0.2,0.211,10,0.6,1.81,0.2,1.29,1.29,0.451,0,0,-0.3,1.9
ENSMUSG00000042901,AIDA,"axin interactor, dorsalization associated",cytoplasm|,multicellular organismal development|dorsal/ventral pattern formation|regulation of protein homodimerization activity|negative regulation of JUN kinase activity|negative regulation of JUN kinase activity|negative regulation of JUN kinase activity|negative regulation of JNK cascade|negative regulation of JNK cascade|negative regulation of JNK cascade|determination of ventral identity|negative regulation of determination of dorsal identity|,protein binding|protein domain specific binding|,10,-0.1,0.525,10,-0.2,0.987,-0.2,1.29,-1.29,0.451,0,0,-1.6,0.9
ENSMUSG00000050002,IDNK,idnK gluconokinase homolog (E. coli),None,carbohydrate metabolic process|biological_process|phosphorylation|,nucleotide binding|molecular_function|ATP binding|kinase activity|transferase activity|gluconokinase activity|,10,0.4,2.39,10,0.1,0.117,0.2,1.25,1.25,0.457,0,0,-0.6,1.8
ENSMUSG00000073877,GM13306,predicted gene 13306,cellular_component|,biological_process|,molecular_function|,2,-0.2,0.673,2,0.5,1.91,-0.3,1.23,-1.23,0.46,0,0,-1.6,2
ENSMUSG00000019872,SMPDL3A,"sphingomyelin phosphodiesterase, acid-like 3A",extracellular region|extracellular space|,sphingomyelin catabolic process|metabolic process|,"cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|photoreceptor cyclic-nucleotide phosphodiesterase activity|sphingomyelin phosphodiesterase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity|inositol phosphosphingolipid phospholipase activity|inositol phosphorylceramide phospholipase activity|mannosyl-inositol phosphorylceramide phospholipase activity|mannosyl-diinositol phosphorylceramide phospholipase activity|",10,0.3,0.666,10,-0.3,1.91,-0.3,1.23,-1.23,0.46,0,0,-1.7,1
ENSMUSG00000030980,KNOP1,lysine rich nucleolar protein 1,nucleus|,None,poly(A) RNA binding|,10,-0.1,0.177,10,0.3,2.17,0.2,1.23,1.23,0.46,0,0,-0.8,1.7
ENSMUSG00000040533,MATN1,"matrilin 1, cartilage matrix protein",extracellular region|proteinaceous extracellular matrix|,chondrocyte differentiation|growth plate cartilage chondrocyte morphogenesis|regulation of bone mineralization|,protein binding|,10,0.6,2.36,10,-0.7,3.07,-0.3,1.22,-1.22,0.462,0,0,-1.8,1.3
ENSMUSG00000039814,XKR5,"X Kell blood group precursor-related family, member 5",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.86,10,-0.2,0.466,-0.2,1.22,-1.22,0.462,0,0,-1.6,1
ENSMUSG00000071178,SERPINA1B,"serine (or cysteine) preptidase inhibitor, clade A, member 1B",extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|extracellular vesicular exosome|,in utero embryonic development|protein N-linked glycosylation|acute-phase response|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,glycoprotein binding|protease binding|endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|protein binding|peptidase inhibitor activity|identical protein binding|,10,0.4,2.05,10,-0.9,1.35,0.3,1.22,1.22,0.462,0,0,-1.9,1.2
ENSMUSG00000029059,FAM213B,"family with sequence similarity 213, member B",cytoplasm|cytoplasm|endoplasmic reticulum|cytosol|myelin sheath|myelin sheath|extracellular vesicular exosome|,prostaglandin biosynthetic process|lipid metabolic process|fatty acid metabolic process|fatty acid biosynthetic process|prostaglandin metabolic process|oxidation-reduction process|,"oxidoreductase activity|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|prostaglandin-F synthase activity|prostaglandin-F synthase activity|",10,0.4,3.11,10,0,0,0.4,1.21,1.21,0.464,0,0,-0.8,1.7
ENSMUSG00000036648,GM3417,predicted gene 3417,cellular_component|,biological_process|,molecular_function|,2,0.6,2.03,2,0,0,0.5,1.2,1.2,0.466,0,0,-1.5,2
ENSMUSG00000000567,SOX9,SRY (sex determining region Y)-box 9,intracellular|intracellular|nucleus|nucleus|transcription factor complex|transcription factor complex|protein complex|nuclear transcription factor complex|,"skeletal system development|cartilage condensation|cell fate specification|epithelial to mesenchymal transition|tissue homeostasis|tissue homeostasis|positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|hair follicle development|positive regulation of mesenchymal cell proliferation|chondrocyte development|negative regulation of immune system process|negative regulation of immune system process|heart valve development|heart valve development|heart valve morphogenesis|heart valve formation|endocardial cushion morphogenesis|chondrocyte differentiation involved in endochondral bone morphogenesis|chondrocyte hypertrophy|chondrocyte hypertrophy|nucleosome assembly|chromatin remodeling|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|protein complex assembly|protein phosphorylation|protein phosphorylation|cytoskeleton organization|signal transduction|signal transduction|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor signaling pathway|spermatogenesis|heart development|positive regulation of cell proliferation|positive regulation of cell proliferation|negative regulation of cell proliferation|male gonad development|male gonad development|male gonad development|regulation of cell cycle process|positive regulation of gene expression|positive regulation of gene expression|positive regulation of epithelial cell migration|positive regulation of epithelial cell migration|positive regulation of epithelial cell migration|neural crest cell development|positive regulation of phosphatidylinositol 3-kinase signaling|positive regulation of phosphatidylinositol 3-kinase signaling|single organismal cell-cell adhesion|male germ-line sex determination|cAMP-mediated signaling|cell differentiation|regulation of cell adhesion|extracellular matrix organization|male sex determination|negative regulation of ossification|negative regulation of ossification|negative regulation of bone mineralization|negative regulation of epithelial cell differentiation|positive regulation of epithelial cell differentiation|otic vesicle formation|endocrine pancreas development|negative regulation of chondrocyte differentiation|positive regulation of chondrocyte differentiation|positive regulation of chondrocyte differentiation|positive regulation of chondrocyte differentiation|somatic stem cell maintenance|intrahepatic bile duct development|regulation of cell proliferation|negative regulation of apoptotic process|negative regulation of apoptotic process|protein kinase B signaling|protein kinase B signaling|cell fate commitment|regulation of cell differentiation|negative regulation of myoblast differentiation|positive regulation of protein catabolic process|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of photoreceptor cell differentiation|oligodendrocyte differentiation|positive regulation of epithelial cell proliferation|positive regulation of epithelial cell proliferation|negative regulation of epithelial cell proliferation|cartilage development|Sertoli cell differentiation|Sertoli cell development|astrocyte fate commitment|retina development in camera-type eye|retinal rod cell differentiation|endochondral bone morphogenesis|epithelial tube branching involved in lung morphogenesis|epithelial tube branching involved in lung morphogenesis|lung epithelial cell differentiation|prostate gland morphogenesis|epithelial cell proliferation involved in prostatic bud elongation|intestinal epithelial structure maintenance|regulation of cell proliferation involved in tissue homeostasis|positive regulation of cartilage development|positive regulation of cartilage development|regulation of branching involved in lung morphogenesis|morphogenesis of a branching epithelium|negative regulation of biomineral tissue development|negative regulation of biomineral tissue development|ERK1 and ERK2 cascade|ERK1 and ERK2 cascade|cellular response to mechanical stimulus|cellular response to mechanical stimulus|cellular response to retinoic acid|cellular response to epidermal growth factor stimulus|cellular response to epidermal growth factor stimulus|cellular response to heparin|cellular response to heparin|cellular response to transforming growth factor beta stimulus|renal vesicle induction|renal vesicle induction|ureter development|ureter smooth muscle cell differentiation|ureter morphogenesis|metanephric nephron tubule formation|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|cochlea morphogenesis|positive regulation of kidney development|positive regulation of kidney development|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of extracellular matrix assembly|positive regulation of male gonad development|positive regulation of cell proliferation involved in heart morphogenesis|positive regulation of mesenchymal stem cell differentiation|regulation of epithelial cell proliferation involved in lung morphogenesis|negative regulation of mesenchymal cell apoptotic process|",transcription regulatory region sequence-specific DNA binding|transcription regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|core promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|enhancer sequence-specific DNA binding|enhancer sequence-specific DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein kinase activity|protein kinase activity|protein binding|beta-catenin binding|protein kinase A catalytic subunit binding|enhancer binding|enhancer binding|bHLH transcription factor binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|pre-mRNA intronic binding|,10,-0.2,0.96,10,-0.9,1.49,-0.4,1.2,-1.2,0.466,0,0,-2,0.2
ENSMUSG00000020374,RASGEF1C,"RasGEF domain family, member 1C",intracellular|,small GTPase mediated signal transduction|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|,10,0.3,0.857,10,0.2,0.5,0.2,1.19,1.19,0.467,0,0,-1,1.6
ENSMUSG00000039210,GPATCH2,G patch domain containing 2,cellular_component|,negative regulation of phosphatase activity|,molecular_function|nucleic acid binding|,10,-0.9,0.131,10,-0.8,1.21,-0.9,1.19,-1.19,0.467,0,0,-2,0.2
ENSMUSG00000042225,AMMECR1,"Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1",cellular_component|,biological_process|,molecular_function|,10,0.4,1.73,10,0.1,0.19,0.2,1.19,1.19,0.467,0,0,-0.8,1.7
ENSMUSG00000026809,1700026L06RIK,RIKEN cDNA 1700026L06 gene,cytoplasmic microtubule|,biological_process|,molecular_function|,10,0.1,0.367,10,0.6,1.28,0.1,1.18,1.18,0.469,0,0,-0.5,2
ENSMUSG00000020193,ZPBP,zona pellucida binding protein,acrosomal vesicle|zona pellucida receptor complex|extracellular region|nucleus|cell body|,acrosome assembly|binding of sperm to zona pellucida|,molecular_function|,10,0.8,3.55,10,0.1,0.0113,0.7,1.17,1.17,0.471,0,0,-0.4,2
ENSMUSG00000078763,SLFN1,schlafen 1,nucleus|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of protein phosphorylation|cell cycle arrest|negative regulation of cell proliferation|negative regulation of T cell proliferation|negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter|negative regulation of G1/S transition of mitotic cell cycle|negative regulation of G1/S transition of mitotic cell cycle|,protein binding|,10,-0.3,1.81,10,0,0,-0.2,1.17,-1.17,0.471,0,0,-1.7,0.8
ENSMUSG00000026739,BMI1,Bmi1 polycomb ring finger oncogene,ubiquitin ligase complex|heterochromatin|nucleus|cytoplasm|nuclear body|PcG protein complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|skeletal system development|in utero embryonic development|DNA methylation|transcription, DNA-templated|regulation of transcription, DNA-templated|humoral immune response|brain development|cellular process|chromatin modification|histone acetylation|histone ubiquitination|rostrocaudal neural tube patterning|positive regulation of B cell proliferation|positive regulation of immature T cell proliferation in thymus|somatic stem cell division|embryonic skeletal system morphogenesis|embryonic skeletal system development|negative regulation of apoptotic signaling pathway|",chromatin binding|ubiquitin-protein transferase activity|protein binding|zinc ion binding|sequence-specific DNA binding|metal ion binding|,10,0.3,2.16,10,0,0,0.2,1.16,1.16,0.473,0,0,-0.6,1.8
ENSMUSG00000029074,TTLL10,"tubulin tyrosine ligase-like family, member 10",cytoplasm|cytoskeleton|microtubule|cilium|axoneme|microtubule cytoskeleton|cell projection|,cellular protein modification process|protein polyglycylation|,"UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0,0,10,-0.7,2.39,-0.2,1.16,-1.16,0.473,0,0,-2,0.3
ENSMUSG00000050612,TXNDC2,thioredoxin domain containing 2 (spermatozoa),outer dense fiber|nucleus|nucleolus|cytoplasm|motile cilium|,protein folding|glycerol ether metabolic process|multicellular organismal development|spermatogenesis|cell differentiation|cell redox homeostasis|oxidation-reduction process|,protein disulfide isomerase activity|thioredoxin-disulfide reductase activity|protein disulfide oxidoreductase activity|,10,-0.2,1.08,10,0.2,1.25,0.2,1.16,1.16,0.473,0,0,-1.4,1.2
ENSMUSG00000051910,SOX6,SRY (sex determining region Y)-box 6,nucleus|nucleus|nucleus|transcription factor complex|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|cell morphogenesis|in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|post-embryonic development|regulation of gene expression|gene silencing|oligodendrocyte cell fate specification|hemopoiesis|erythrocyte differentiation|positive regulation of chondrocyte differentiation|positive regulation of chondrocyte differentiation|muscle cell differentiation|cell fate commitment|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|astrocyte differentiation|oligodendrocyte differentiation|erythrocyte development|cartilage development|cardiac muscle cell differentiation|positive regulation of cartilage development|cellular response to transforming growth factor beta stimulus|positive regulation of mesenchymal stem cell differentiation|",DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|sequence-specific DNA binding|transcription regulatory region DNA binding|protein heterodimerization activity|,10,0.2,1.55,10,0,0,0.2,1.16,1.16,0.473,0,0,-1.1,1.5
ENSMUSG00000026095,ASNSD1,asparagine synthetase domain containing 1,cellular_component|,asparagine biosynthetic process|glutamine metabolic process|biological_process|metabolic process|cellular amino acid biosynthetic process|,molecular_function|asparagine synthase (glutamine-hydrolyzing) activity|,10,0.9,1.8,10,-0.3,1.26,-0.2,1.15,-1.15,0.475,0,0,-1.7,1.7
ENSMUSG00000038893,FAM117A,"family with sequence similarity 117, member A",cellular_component|,biological_process|,molecular_function|,10,-1.2,3.96,10,0,0,-0.3,1.15,-1.15,0.475,0,0,-2,0.2
ENSMUSG00000031274,COL4A5,"collagen, type IV, alpha 5",collagen trimer|collagen type IV trimer|basement membrane|basal lamina|neuromuscular junction|,neuromuscular junction development|,None,10,-0.1,0.00665,10,0.2,1.82,0.2,1.14,1.14,0.477,0,0,-0.8,1.7
ENSMUSG00000052748,SWT1,SWT1 RNA endoribonuclease homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,0.1,0.528,10,-0.8,1.55,0.2,1.13,1.13,0.478,0,0,-2,0.7
ENSMUSG00000071708,SMS,spermine synthase,extracellular vesicular exosome|,spermine biosynthetic process|spermine metabolic process|,spermine synthase activity|spermine synthase activity|,10,0.8,1.6,10,-0.4,1.65,0.6,1.13,1.13,0.478,0,0,-0.8,2
ENSMUSG00000035539,E230008N13RIK,RIKEN cDNA E230008N13 gene,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.8,1.07,10,-0.3,0.72,-0.2,1.12,-1.12,0.48,0,0,-2,0.3
ENSMUSG00000035614,FAM179B,"family with sequence similarity 179, member B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.8,3.15,-0.3,1.12,-1.12,0.48,0,0,-2,0.9
ENSMUSG00000070306,CCDC153,coiled-coil domain containing 153,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.87,10,0.1,0.454,-0.2,1.12,-1.12,0.48,0,0,-1.5,1.1
ENSMUSG00000029586,4933411G11RIK,RIKEN cDNA 4933411G11Rik gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.589,10,0.8,1.68,0.1,1.11,1.11,0.482,0,0,-0.4,2
ENSMUSG00000030074,GXYLT2,glucoside xylosyltransferase 2,cellular_component|membrane|integral component of membrane|,O-glycan processing|,"transferase activity|transferase activity, transferring glycosyl groups|UDP-xylosyltransferase activity|",10,0,0,10,0.2,1.86,0.2,1.11,1.11,0.482,0,0,-0.8,1.7
ENSMUSG00000035367,RMI1,"RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)",nucleus|,response to dietary excess|reduction of food intake in response to dietary excess|DNA replication|response to glucose|multicellular organism growth|glucose homeostasis|,molecular_function|,2,0.4,1.58,2,-0.6,1.64,0.3,1.09,1.09,0.486,0,0,-2,1.7
ENSMUSG00000024053,EMILIN2,elastin microfibril interfacer 2,extracellular region|proteinaceous extracellular matrix|collagen trimer|,cell adhesion|,None,10,0.6,3.5,10,0,0,0.1,1.09,1.09,0.486,0,0,-0.2,2
ENSMUSG00000046562,UNC119B,unc-119 homolog B (C. elegans),cilium|ciliary transition zone|cell projection|,transport|protein transport|cell projection organization|lipoprotein transport|cilium morphogenesis|,lipid binding|,10,0.5,3.14,10,-0.1,0.195,0.3,1.08,1.08,0.487,0,0,-0.5,1.9
ENSMUSG00000029559,2210016L21RIK,RIKEN cDNA 2210016L21 gene,cellular_component|,biological_process|,molecular_function|,9,0.3,2.68,9,-0.8,1.15,0.2,1.08,1.08,0.487,0,0,-1.9,1.2
ENSMUSG00000079484,PHYHD1,phytanoyl-CoA dioxygenase domain containing 1,cellular_component|,biological_process|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|dioxygenase activity|epoxyqueuosine reductase activity|,10,0.1,0.0383,10,-0.4,1.96,-0.4,1.07,-1.07,0.49,0,0,-1.8,0.6
ENSMUSG00000039195,1110008P14RIK,RIKEN cDNA 1110008P14 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,1.42,10,0.4,0.0732,0.2,1.05,1.05,0.494,0,0,-0.8,1.7
ENSMUSG00000041471,FAM35A,"family with sequence similarity 35, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,1.36,-0.2,1.05,-1.05,0.494,0,0,-1.7,0.8
ENSMUSG00000035963,ODF3L2,outer dense fiber of sperm tails 3-like 2,cytoplasmic microtubule|,biological_process|,molecular_function|,10,0.3,1.25,10,0,0,0.2,1.05,1.05,0.494,0,0,-0.8,1.8
ENSMUSG00000039976,TBC1D16,"TBC1 domain family, member 16",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,2.36,0.2,1.03,1.03,0.498,0,0,-0.9,1.7
ENSMUSG00000008028,1700008O03RIK,RIKEN cDNA 1700008O03 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,1.15,10,-0.4,2.15,0.1,1.02,1.02,0.5,0,0,-1.6,1.1
ENSMUSG00000033706,SMYD5,SET and MYND domain containing 5,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.1,0.546,10,0.1,0.567,0.1,1.02,1.02,0.5,0,0,-1,1.7
ENSMUSG00000048277,SYNGR2,synaptogyrin 2,intracellular|cell|synaptic vesicle|membrane|integral component of membrane|cytoplasmic vesicle|extracellular vesicular exosome|,protein targeting|,None,10,0.5,1.83,10,0.1,0.444,0.3,1.01,1.01,0.502,0,0,-1.1,1.6
ENSMUSG00000091264,SMIM13,small integral membrane protein 13,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.598,10,0.4,1.18,0.2,1.01,1.01,0.502,0,0,-0.8,1.7
ENSMUSG00000075573,DEFB47,defensin beta 47,cellular_component|,biological_process|,molecular_function|,10,0.2,1.82,10,-0.2,0.126,0.2,0.971,0.971,0.51,0,0,-1.2,1.5
ENSMUSG00000043068,FAM89A,"family with sequence similarity 89, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,1.76,-0.3,0.954,-0.954,0.514,0,0,-1.7,1
ENSMUSG00000016763,SCUBE1,"signal peptide, CUB domain, EGF-like 1",extracellular region|plasma membrane|external side of plasma membrane|cell surface|membrane|,protein homooligomerization|,calcium ion binding|protein heterodimerization activity|,10,0,0,10,0.3,3.1,0.3,0.954,0.954,0.514,0,0,-0.5,1.9
ENSMUSG00000022799,ARHGAP31,Rho GTPase activating protein 31,intracellular|lamellipodium|cell junction|cell projection|,signal transduction|small GTPase mediated signal transduction|positive regulation of GTPase activity|,GTPase activator activity|protein binding|SH3 domain binding|,10,0,0,10,-1.1,3.91,-1,0.952,-0.952,0.514,0,0,-2,0.2
ENSMUSG00000032258,LCA5,Leber congenital amaurosis 5 (human),intracellular|cell|cytoplasm|cytoskeleton|cilium|cilium|cilium|cell projection|,transport|protein transport|intraciliary transport|photoreceptor cell maintenance|,protein complex binding|,10,-0.2,0.685,10,-0.2,0.351,-0.2,0.952,-0.952,0.514,0,0,-1.6,1
ENSMUSG00000036480,PRSS56,"protease, serine 56",endoplasmic reticulum|membrane|,proteolysis|camera-type eye development|camera-type eye development|,catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.2,1.52,10,0,0,-0.2,0.95,-0.95,0.514,0,0,-1.8,0.8
ENSMUSG00000091537,TMA7,translational machinery associated 7 homolog (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,8,0.1,0.124,8,0.7,2.16,0.1,0.946,0.946,0.515,0,0,-0.7,2
ENSMUSG00000034035,CCDC17,coiled-coil domain containing 17,None,None,None,10,-0.1,0.748,10,0.3,2.19,-0.1,0.939,-0.939,0.517,0,0,-1.1,1.6
ENSMUSG00000005131,4930550C14RIK,RIKEN cDNA 4930550C14 gene,cellular_component|,biological_process|,molecular_function|,10,0.4,1.35,10,-0.3,0.11,0.3,0.926,0.926,0.519,0,0,-1.1,1.6
ENSMUSG00000014867,SURF4,surfeit gene 4,endoplasmic reticulum|endoplasmic reticulum-Golgi intermediate compartment|Golgi apparatus|membrane|integral component of membrane|,Golgi organization|positive regulation of organelle organization|,None,10,0,0,10,-0.3,2.28,-0.3,0.923,-0.923,0.52,0,0,-1.9,0.5
ENSMUSG00000035642,AAMDC,adipogenesis associated Mth938 domain containing,cytoplasm|,negative regulation of apoptotic process|positive regulation of fat cell differentiation|positive regulation of fat cell differentiation|positive regulation of transcription from RNA polymerase II promoter|,molecular_function|,10,0.3,1.74,10,-0.2,1.23,-0.2,0.918,-0.918,0.521,0,0,-1.3,1.3
ENSMUSG00000043629,1700019D03RIK,RIKEN cDNA 1700019D03 gene,cellular_component|plasma membrane|membrane|,biological_process|,molecular_function|protein kinase A regulatory subunit binding|,10,0.1,0.0487,10,-0.3,1.79,-0.2,0.904,-0.904,0.524,0,0,-1.3,1.3
ENSMUSG00000010048,IFRD2,interferon-related developmental regulator 2,nucleus|,biological_process|,molecular_function|,10,-0.5,1.01,10,0.2,1.34,0.1,0.902,0.902,0.524,0,0,-1.7,1.1
ENSMUSG00000038594,CEP85L,centrosomal protein 85-like,cellular_component|,biological_process|,molecular_function|,10,0.3,2.09,10,0,0,0.2,0.9,0.9,0.525,0,0,-0.8,1.8
ENSMUSG00000028415,SPINK4,"serine peptidase inhibitor, Kazal type 4",extracellular region|,negative regulation of peptidase activity|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.8,0.961,10,-0.1,0.275,-0.1,0.9,-0.9,0.525,0,0,-2,0.5
ENSMUSG00000026885,TTLL11,"tubulin tyrosine ligase-like family, member 11",cellular_component|cytoplasm|cytoskeleton|cilium|cell projection|,cellular protein modification process|protein polyglutamylation|microtubule severing|microtubule severing|,molecular_function|ligase activity|,10,-0.2,0.497,10,-0.2,0.472,-0.2,0.889,-0.889,0.527,0,0,-1.6,1
ENSMUSG00000026694,METTL13,methyltransferase like 13,cellular_component|,biological_process|metabolic process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|catalytic activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.4,0.342,10,-0.3,0.672,-0.3,0.888,-0.888,0.528,0,0,-1.7,0.8
ENSMUSG00000045751,MMS22L,"MMS22-like, DNA repair protein",nucleus|FACT complex|MCM complex|nuclear replication fork|,double-strand break repair via homologous recombination|DNA repair|cellular response to DNA damage stimulus|replication fork processing|,molecular_function|,8,-0.2,0.29,9,0.6,2.75,0.5,0.885,0.885,0.528,0,0,-1.6,1.6
ENSMUSG00000027259,ADAL,adenosine deaminase-like,cellular_component|,adenosine catabolic process|nucleotide metabolic process|inosine biosynthetic process|,"GTP cyclohydrolase activity|adenosine deaminase activity|adenosine deaminase activity|tRNA-specific adenosine deaminase activity|hydrolase activity|deaminase activity|N-cyclopropylmelamine deaminase activity|N-cyclopropylammeline deaminase activity|N-cyclopropylammelide alkylamino hydrolase activity|2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity|tRNA-specific adenosine-37 deaminase activity|archaeal-specific GTP cyclohydrolase activity|metal ion binding|tRNA-specific adenosine-34 deaminase activity|",10,0.4,1.94,9,-0.1,0.158,0.3,0.881,0.881,0.529,0,0,-0.8,1.8
ENSMUSG00000071177,SERPINA1D,"serine (or cysteine) peptidase inhibitor, clade A, member 1D",extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|extracellular vesicular exosome|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,glycoprotein binding|protease binding|endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|identical protein binding|,10,0.3,2.03,10,0,0,0.2,0.878,0.878,0.53,0,0,-0.7,1.8
ENSMUSG00000026921,EGFL7,EGF-like domain 7,extracellular region|extracellular space|,angiogenesis|positive regulation of endothelial cell proliferation|cell adhesion|multicellular organismal development|cell differentiation|regulation of cell migration|negative regulation of cell migration|negative regulation of Notch signaling pathway|,Notch binding|calcium ion binding|,7,-0.3,1.09,7,0.5,1.09,-0.2,0.876,-0.876,0.53,0,0,-1.3,1.8
ENSMUSG00000035179,PPP1R32,"protein phosphatase 1, regulatory subunit 32",cellular_component|,biological_process|,phosphatase binding|,10,-0.7,3.67,10,0.3,0.57,-0.7,0.875,-0.875,0.53,0,0,-2,0.8
ENSMUSG00000032261,SH3BGRL2,SH3 domain binding glutamic acid-rich protein like 2,nucleus|extracellular vesicular exosome|,biological_process|,molecular_function|SH3 domain binding|,10,0.4,1.99,10,1.3,2.02,1.1,0.871,0.871,0.531,0,0,-1.5,2
ENSMUSG00000045975,C2CD2,C2 calcium-dependent domain containing 2,nucleus|cytosol|,biological_process|,molecular_function|,10,0.1,0.17,10,0.2,0.828,0.1,0.87,0.87,0.532,0,0,-1.8,1
ENSMUSG00000010064,SLC38A3,"solute carrier family 38, member 3",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|drug transmembrane transport|amino acid transport|asparagine transport|glutamine transport|glutamine transport|L-alanine transport|histidine transport|histidine transport|L-alpha-amino acid transmembrane transport|,L-histidine transmembrane transporter activity|L-histidine transmembrane transporter activity|L-alanine transmembrane transporter activity|L-asparagine transmembrane transporter activity|L-glutamine transmembrane transporter activity|L-glutamine transmembrane transporter activity|symporter activity|antiporter activity|,10,0.3,1.54,10,0,0,0.2,0.869,0.869,0.532,0,0,-1.4,1.4
ENSMUSG00000089876,TMEM102,transmembrane protein 102,intracellular|plasma membrane|cell surface|membrane|integral component of membrane|protein complex|,apoptotic process|signal transduction|positive regulation of T cell chemotaxis|response to cytokine|regulation of apoptotic process|positive regulation of cell adhesion|positive regulation of cell adhesion|positive regulation of cell adhesion|regulation of peptidyl-tyrosine phosphorylation|regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway|positive regulation of T cell migration|positive regulation of T cell migration|positive regulation of T cell migration|,molecular_function|,10,-0.4,1.51,10,0.1,0.0361,-0.2,0.865,-0.865,0.533,0,0,-1.8,0.7
ENSMUSG00000030771,MICALCL,MICAL C-terminal like,cytoplasm|,multicellular organismal development|spermatogenesis|cell differentiation|,mitogen-activated protein kinase binding|,9,0.1,0.662,9,0.2,0.295,0.2,0.862,0.862,0.533,0,0,-1,1.8
ENSMUSG00000035992,FNIP1,folliculin interacting protein 1,cytoplasm|cytoplasm|,negative regulation of transcription from RNA polymerase II promoter|regulation of protein phosphorylation|positive regulation of protein phosphorylation|immature B cell differentiation|positive regulation of B cell apoptotic process|positive regulation of B cell apoptotic process|cellular response to starvation|TOR signaling|negative regulation of TOR signaling|positive regulation of peptidyl-serine phosphorylation|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|positive regulation of GTPase activity|regulation of pro-B cell differentiation|,guanyl-nucleotide exchange factor activity|protein binding|,10,0.1,0.351,10,0.2,0.766,0.2,0.85,0.85,0.536,0,0,-0.9,1.7
ENSMUSG00000043065,SPICE1,spindle and centriole associated protein 1,cytoplasm|centrosome|centriole|spindle|cytoskeleton|,cell cycle|mitotic nuclear division|regulation of centriole replication|cell division|metaphase plate congression|spindle assembly involved in mitosis|,molecular_function|,10,-0.3,1.08,10,-0.1,0.13,-0.2,0.844,-0.844,0.537,0,0,-1.8,0.8
ENSMUSG00000024213,NUDT3,nudix (nucleotide diphosphate linked moiety X)-type motif 3,extracellular vesicular exosome|,diphosphoinositol polyphosphate catabolic process|,magnesium ion binding|diphosphoinositol-polyphosphate diphosphatase activity|,9,0.2,0.326,9,0.1,0.591,0.2,0.841,0.841,0.538,0,0,-1,1.8
ENSMUSG00000056665,THEM6,thioesterase superfamily member 6,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.1,0.218,10,0.3,1.06,0.2,0.838,0.838,0.539,0,0,-1.5,1.4
ENSMUSG00000027122,ARL14EP,ADP-ribosylation factor-like 14 effector protein,cytoplasm|,biological_process|,molecular_function|,10,-0.5,0.0262,10,0.3,2.42,0.2,0.837,0.837,0.539,0,0,-1.4,1.5
ENSMUSG00000049516,SPTY2D1,"SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.4,2.14,0.3,0.836,0.836,0.539,0,0,-1.4,1.5
ENSMUSG00000061356,NUGGC,"nuclear GTPase, germinal center associated",nucleus|,cellular response to DNA damage stimulus|somatic hypermutation of immunoglobulin genes|,molecular_function|,10,0.9,1.98,10,0,0,0.7,0.835,0.835,0.539,0,0,-0.4,2
ENSMUSG00000061410,ZCCHC14,"zinc finger, CCHC domain containing 14",cellular_component|,biological_process|,molecular_function|nucleic acid binding|zinc ion binding|phosphatidylinositol binding|metal ion binding|,10,-0.9,0.355,10,0.5,2.99,0.4,0.83,0.83,0.541,0,0,-1.7,1.5
ENSMUSG00000045752,TSSC4,tumor-suppressing subchromosomal transferable fragment 4,cellular_component|,biological_process|,molecular_function|,10,0.1,0.456,10,0.1,0.445,0.1,0.826,0.826,0.541,0,0,-1.1,1.6
ENSMUSG00000029624,PTCD1,pentatricopeptide repeat domain 1,mitochondrion|mitochondrial matrix|,tRNA processing|biological_process|,molecular_function|,9,0.4,2.04,8,0,0,0.3,0.822,0.822,0.542,0,0,-1,1.8
ENSMUSG00000042388,DLGAP3,"discs, large (Drosophila) homolog-associated protein 3",plasma membrane|membrane|N-methyl-D-aspartate selective glutamate receptor complex|cell junction|neuronal cell body|dendritic spine|synapse|postsynaptic membrane|,protein complex assembly|cell-cell signaling|,beta-amyloid binding|protein domain specific binding|PDZ domain binding|protein complex scaffold|scaffold protein binding|,10,0.1,0.485,10,0.1,0.404,0.1,0.815,0.815,0.544,0,0,-1,1.7
ENSMUSG00000038214,BEND3,BEN domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0.2,1.49,10,-0.3,1.09,0.2,0.815,0.815,0.544,0,0,-1.3,1.4
ENSMUSG00000051113,FAM71E1,"family with sequence similarity 71, member E1",cellular_component|,biological_process|,molecular_function|,10,0.1,0.637,10,0.1,0.247,0.1,0.812,0.812,0.544,0,0,-1.1,1.6
ENSMUSG00000030792,DKKL1,dickkopf-like 1,extracellular region|,positive regulation of fat cell differentiation|,protein binding|,10,-0.4,0.802,10,0.4,1.64,0.3,0.79,0.79,0.55,0,0,-1.6,1.2
ENSMUSG00000039958,METTL20,methyltransferase like 20,cellular_component|cytoplasm|,protein methylation|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.2,0.762,10,0.1,0.196,0.2,0.786,0.786,0.551,0,0,-1.5,1.4
ENSMUSG00000000686,ABHD15,abhydrolase domain containing 15,extracellular region|membrane|,biological_process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.2,1.63,10,0.2,0.963,-0.2,0.779,-0.779,0.553,0,0,-1.4,1.3
ENSMUSG00000029272,SULT1E1,"sulfotransferase family 1E, member 1",cytoplasm|,female pregnancy|estrogen metabolic process|estrogen metabolic process|estrogen metabolic process|sulfation|,estrone sulfotransferase activity|steroid binding|sulfotransferase activity|lipid binding|transferase activity|flavonol 3-sulfotransferase activity|steroid sulfotransferase activity|steroid sulfotransferase activity|,10,0.2,0.888,10,-0.2,0.773,0.2,0.775,0.775,0.553,0,0,-1.2,1.5
ENSMUSG00000021091,SERPINA3N,"serine (or cysteine) peptidase inhibitor, clade A, member 3N",extracellular region|extracellular space|extracellular vesicular exosome|blood microparticle|,acute-phase response|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|response to cytokine|response to peptide hormone|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0.8,2.21,0.2,0.773,0.773,0.554,0,0,-0.5,2
ENSMUSG00000030030,1700003E16RIK,RIKEN cDNA 1700003E16 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.12,10,0.3,1.96,0.2,0.771,0.771,0.554,0,0,-0.8,1.8
ENSMUSG00000015542,NAT9,"N-acetyltransferase 9 (GCN5-related, putative)",protein complex|,biological_process|,"molecular_function|dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.2,1.36,10,0,0,0.2,0.766,0.766,0.555,0,0,-0.8,1.8
ENSMUSG00000036160,SURF6,surfeit gene 6,granular component|nucleus|nucleoplasm|nucleolus|,ribosome biogenesis|ribosome assembly|,DNA binding|RNA binding|poly(A) RNA binding|,10,0,0,10,-0.9,3.24,-0.7,0.76,-0.76,0.557,0,0,-2,0.2
ENSMUSG00000030410,DMWD,dystrophia myotonica-containing WD repeat motif,cellular_component|,biological_process|,molecular_function|,10,0.3,2.35,10,-0.1,0.313,0.3,0.752,0.752,0.559,0,0,-1.3,1.4
ENSMUSG00000038544,INIP,INTS3 and NABP interacting protein,nucleus|SOSS complex|,DNA repair|cellular response to DNA damage stimulus|response to ionizing radiation|,molecular_function|,10,-0.4,0.193,10,0.7,2.14,0.1,0.743,0.743,0.561,0,0,-1,2
ENSMUSG00000024732,CCDC86,coiled-coil domain containing 86,nucleus|nucleus|nucleolus|,None,poly(A) RNA binding|,10,0.1,0.251,10,0.1,0.552,0.1,0.737,0.737,0.562,0,0,-1.5,1.4
ENSMUSG00000047749,ZC3HAV1L,"zinc finger CCCH-type, antiviral 1-like",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.5,3.06,10,-0.2,0.434,0.4,0.737,0.737,0.562,0,0,-0.9,1.8
ENSMUSG00000021679,S100Z,"S100 calcium binding protein, zeta",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.3,1.38,10,0,0,0.2,0.733,0.733,0.563,0,0,-0.9,1.7
ENSMUSG00000013921,CLIP3,CAP-GLY domain containing linker protein 3,cytoplasm|Golgi apparatus|trans-Golgi network|plasma membrane|plasma membrane|membrane|early endosome membrane|trans-Golgi network membrane|membrane raft|recycling endosome membrane|,positive regulation of protein phosphorylation|positive regulation of glucose transport|peptidyl-L-cysteine S-palmitoylation|negative regulation of microtubule polymerization|positive regulation of apoptotic process|membrane biogenesis|positive regulation of endocytosis|chaperone-mediated protein transport|positive regulation of establishment of protein localization to plasma membrane|,protein binding|microtubule binding|ganglioside binding|,10,0.4,0.319,10,-0.2,0.967,-0.2,0.732,-0.732,0.563,0,0,-1.4,1.5
ENSMUSG00000087236,GM1305,predicted gene 1305,cellular_component|microtubule|,biological_process|,nucleotide binding|molecular_function|ATP binding|,9,-0.1,0.135,9,-0.7,1.47,-0.2,0.731,-0.731,0.564,0,0,-2,0.7
ENSMUSG00000042831,ALKBH6,"alkB, alkylation repair homolog 6 (E. coli)",cellular_component|nucleus|cytoplasm|,biological_process|oxidation-reduction process|,"sulfonate dioxygenase activity|oxidoreductase activity|2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity|procollagen-proline dioxygenase activity|hypophosphite dioxygenase activity|DNA-N1-methyladenine dioxygenase activity|metal ion binding|dioxygenase activity|C-19 gibberellin 2-beta-dioxygenase activity|C-20 gibberellin 2-beta-dioxygenase activity|",10,0.1,0.113,10,0.7,0.89,0.1,0.73,0.73,0.564,0,0,-0.4,2
ENSMUSG00000037134,PRMT10,protein arginine methyltransferase 10 (putative),cellular_component|cytoplasm|,protein methylation|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.4,1.13,10,-0.1,0.362,-0.3,0.727,-0.727,0.565,0,0,-1.9,0.6
ENSMUSG00000049723,MMP12,matrix metallopeptidase 12,extracellular region|proteinaceous extracellular matrix|extracellular matrix|,"proteolysis|wound healing, spreading of epidermal cells|wound healing|positive regulation of epithelial cell proliferation involved in wound healing|",metalloendopeptidase activity|calcium ion binding|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.4,0.601,9,0.1,0.641,0.2,0.725,0.725,0.565,0,0,-0.7,1.9
ENSMUSG00000019775,RGS17,regulator of G-protein signaling 17,nucleus|cytoplasm|plasma membrane|membrane|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|GTPase activator activity|,10,0.1,0.167,10,0.2,0.637,0.1,0.724,0.724,0.565,0,0,-1.2,1.5
ENSMUSG00000046567,4930430F08RIK,RIKEN cDNA 4930430F08 gene,cellular_component|,hematopoietic progenitor cell differentiation|,molecular_function|,9,0.9,3.02,9,0,0,0.2,0.716,0.716,0.567,0,0,-0.9,2
ENSMUSG00000055660,METTL4,methyltransferase like 4,cellular_component|,nucleobase-containing compound metabolic process|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,0.94,10,-1,1.67,-0.1,0.715,-0.715,0.568,0,0,-2,0.3
ENSMUSG00000036114,RPP25L,ribonuclease P/MRP 25 subunit-like,cellular_component|nucleus|,biological_process|,nucleic acid binding|poly(A) RNA binding|,7,0.5,1.7,8,0,0,0.2,0.712,0.712,0.568,0,0,-0.8,2
ENSMUSG00000069920,B3GNT9,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9",Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.1,0.0619,10,0.2,0.927,0.2,0.709,0.709,0.569,0,0,-1.3,1.5
ENSMUSG00000041287,SOX15,SRY (sex determining region Y)-box 15,nucleus|cytoplasm|nuclear transcription factor complex|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|positive regulation of satellite cell activation involved in skeletal muscle regeneration|cell differentiation|skeletal muscle tissue regeneration|negative regulation of striated muscle tissue development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|myoblast development|positive regulation of G0 to G1 transition|positive regulation of myoblast proliferation|,sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|DNA binding|chromatin binding|protein binding|protein heterodimerization activity|,10,0.6,3.3,10,-0.4,0.967,0.5,0.702,0.702,0.571,0,0,-1.1,1.8
ENSMUSG00000024786,1700123I01RIK,RIKEN cDNA 1700123I01 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.08,10,0.1,0.23,-0.2,0.701,-0.701,0.571,0,0,-1.5,1.2
ENSMUSG00000024973,HRASLS5,"HRAS-like suppressor family, member 5",None,None,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0.2,0.516,10,0.5,1.2,0.4,0.694,0.694,0.573,0,0,-0.6,1.9
ENSMUSG00000025743,SDC3,syndecan 3,membrane|integral component of membrane|axon|neuron projection|protein complex|,cell adhesion|,cytoskeletal protein binding|,10,0.2,1,10,0,0,0.1,0.691,0.691,0.574,0,0,-1,1.7
ENSMUSG00000017002,SLPI,secretory leukocyte peptidase inhibitor,extracellular region|extracellular matrix|extracellular vesicular exosome|,proteolysis|negative regulation of peptidase activity|negative regulation of protein binding|negative regulation of viral genome replication|,serine-type endopeptidase inhibitor activity|peptidase activity|hydrolase activity|enzyme binding|peptidase inhibitor activity|,10,0.1,0.303,10,0.1,0.45,0.1,0.69,0.69,0.574,0,0,-1.1,1.7
ENSMUSG00000037020,WDR62,WD repeat domain 62,spindle pole|nucleus|cytoplasm|cytoskeleton|,cerebral cortex development|neurogenesis|,molecular_function|,10,-0.3,0.0145,10,-0.3,0.726,-0.3,0.683,-0.683,0.576,0,0,-1.7,1.1
ENSMUSG00000069814,E130309D14RIK,RIKEN cDNA E130309D14 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.552,10,-0.1,0.233,-0.1,0.679,-0.679,0.577,0,0,-1.3,1.6
ENSMUSG00000073684,2610002J02RIK,RIKEN cDNA 2610002J02 gene,nucleus|chromosome|cell junction|Fanconi anaemia nuclear complex|,DNA repair|cellular response to DNA damage stimulus|translesion synthesis|interstrand cross-link repair|,polyubiquitin binding|ubiquitin binding|metal ion binding|K63-linked polyubiquitin binding|,10,0.2,0.799,10,0.1,0.102,0.1,0.671,0.671,0.579,0,0,-1.4,1.4
ENSMUSG00000012889,PODNL1,podocan-like 1,cellular_component|extracellular region|proteinaceous extracellular matrix|,biological_process|,molecular_function|,10,0.1,0.125,10,0.1,0.598,0.1,0.664,0.664,0.581,0,0,-1.2,1.6
ENSMUSG00000029461,FAM168A,"family with sequence similarity 168, member A",cellular_component|,biological_process|,molecular_function|,10,0.7,0.44,10,0.2,0.734,0.1,0.663,0.663,0.581,0,0,-0.5,2
ENSMUSG00000095573,GM16501,predicted gene 16501,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.59,10,0,0,-0.2,0.627,-0.627,0.591,0,0,-1.7,1
ENSMUSG00000049555,TMIE,transmembrane inner ear,membrane|integral component of membrane|,sensory perception of sound|inner ear morphogenesis|,None,10,0.1,0.402,10,0.1,0.282,0.1,0.626,0.626,0.591,0,0,-1.7,1.2
ENSMUSG00000040219,TTC12,tetratricopeptide repeat domain 12,cellular_component|,biological_process|,molecular_function|,10,0.1,0.024,10,0.2,0.741,0.1,0.618,0.618,0.593,0,0,-1.1,1.7
ENSMUSG00000006784,TTC25,tetratricopeptide repeat domain 25,cytoplasm|,biological_process|,molecular_function|,10,-0.1,0.00691,10,-0.2,1.09,-0.1,0.615,-0.615,0.594,0,0,-1.5,1.4
ENSMUSG00000015787,ABO,"ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase)",extracellular region|Golgi apparatus|membrane|integral component of membrane|cytoplasmic vesicle|,carbohydrate metabolic process|,"alpha-1,3-galactosyltransferase activity|glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity|glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity|fucosylgalactoside 3-alpha-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|metal ion binding|",10,0.2,0.528,10,-0.5,1.22,0.1,0.615,0.615,0.594,0,0,-1.3,1.8
ENSMUSG00000024696,LPXN,leupaxin,podosome|podosome|nucleus|nucleus|cytoplasm|plasma membrane|focal adhesion|focal adhesion|membrane|membrane|cell junction|cell projection|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cell adhesion|negative regulation of cell adhesion|regulation of cell adhesion mediated by integrin|negative regulation of B cell receptor signaling pathway|negative regulation of B cell receptor signaling pathway|regulation of RNA biosynthetic process|",transcription cofactor activity|transcription cofactor activity|protein binding|zinc ion binding|metal ion binding|,10,0.4,0.75,10,0.1,0.431,0.1,0.614,0.614,0.594,0,0,-0.8,1.8
ENSMUSG00000063663,BRWD3,bromodomain and WD repeat domain containing 3,cellular_component|,cytoskeleton organization|regulation of cell shape|,molecular_function|,10,0,0,10,0.5,2.78,0.4,0.6,0.6,0.598,0,0,-1.1,1.8
ENSMUSG00000024131,SLC3A1,"solute carrier family 3, member 1",mitochondrial inner membrane|vacuolar membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|brush border membrane|brush border membrane|extracellular vesicular exosome|,carbohydrate metabolic process|transport|amino acid transport|,catalytic activity|protein binding|cation binding|protein heterodimerization activity|,10,-0.1,0.372,10,-0.2,0.275,-0.1,0.583,-0.583,0.603,0,0,-1.6,1.3
ENSMUSG00000040225,PRRC2C,proline-rich coiled-coil 2C,membrane|,hematopoietic progenitor cell differentiation|,protein C-terminus binding|poly(A) RNA binding|,10,-0.2,0.17,10,-0.3,0.502,-0.3,0.575,-0.575,0.605,0,0,-1.9,0.7
ENSMUSG00000079033,MEF2B,myocyte enhancer factor 2B,nucleus|nucleus|transcription factor complex|cytoplasm|cell junction|,"regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|sequence-specific DNA binding transcription factor activity|histone deacetylase binding|,3,-0.1,0.0854,3,0.6,1.83,0.5,0.575,0.575,0.605,0,0,-1.4,2
ENSMUSG00000074651,MCIDAS,multiciliate differentiation and DNA synthesis associated cell cycle protein,nucleus|,"regulation of DNA replication|transcription, DNA-templated|regulation of transcription, DNA-templated|cell cycle|regulation of mitotic cell cycle|cell projection organization|",identical protein binding|,10,0,0,10,0.3,2.2,0.2,0.574,0.574,0.606,0,0,-0.7,1.9
ENSMUSG00000043336,FILIP1L,filamin A interacting protein 1-like,cellular_component|nucleus|cytoplasm|membrane|,biological_process|,molecular_function|,10,0.2,0.586,9,0.1,0.195,0.2,0.573,0.573,0.606,0,0,-1.4,1.5
ENSMUSG00000027536,CHMP4C,charged multivesicular body protein 4C,cytoplasm|endosome|membrane|midbody|extracellular vesicular exosome|Flemming body|,transport|bioluminescence|abscission|protein transport|cytokinesis checkpoint|negative regulation of cytokinesis|regulation of viral process|positive regulation of viral release from host cell|,protein homodimerization activity|,10,-0.1,0.0178,10,-0.3,1.02,-0.1,0.568,-0.568,0.607,0,0,-1.7,1
ENSMUSG00000070643,SOX13,SRY (sex determining region Y)-box 13,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of gamma-delta T cell differentiation|",DNA binding|sequence-specific DNA binding|,10,0,0,10,-0.2,0.863,-0.1,0.567,-0.567,0.608,0,0,-1.7,1.1
ENSMUSG00000020925,CCDC43,coiled-coil domain containing 43,cellular_component|,biological_process|,molecular_function|,10,0.2,0.231,10,0.1,0.495,0.2,0.565,0.565,0.608,0,0,-0.8,1.9
ENSMUSG00000041372,B4GALNT3,"beta-1,4-N-acetyl-galactosaminyl transferase 3",Golgi apparatus|membrane|integral component of membrane|Golgi cisterna membrane|,metabolic process|,acetylgalactosaminyltransferase activity|acetylgalactosaminyltransferase activity|transferase activity|N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity|,10,-0.3,1.72,10,0.7,1.02,-0.2,0.551,-0.551,0.612,0,0,-1.1,1.9
ENSMUSG00000032567,ASTE1,asteroid homolog 1 (Drosophila),cellular_component|,biological_process|,molecular_function|,10,-0.2,0.609,10,-0.1,0.0213,-0.1,0.55,-0.55,0.613,0,0,-1.8,0.9
ENSMUSG00000022228,ZSCAN26,zinc finger and SCAN domain containing 26,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",nucleic acid binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.2,1.15,10,-0.1,0.00226,0.1,0.549,0.549,0.613,0,0,-1.2,1.6
ENSMUSG00000028854,SLC9A1,"solute carrier family 9 (sodium/hydrogen exchanger), member 1",nucleus|cytoplasm|mitochondrion|endoplasmic reticulum|plasma membrane|cell surface|intercalated disc|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|T-tubule|sarcolemma|membrane raft|perinuclear region of cytoplasm|extracellular vesicular exosome|,response to acid|regulation of the force of heart contraction|transport|ion transport|cation transport|sodium ion transport|regulation of pH|regulation of pH|regulation of pH|embryo development|response to acidity|response to acidity|response to organic cyclic compound|positive regulation of cell growth|cellular response to insulin stimulus|sodium ion transmembrane transport|positive regulation of mitochondrial membrane permeability|positive regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of action potential|regulation of intracellular pH|regulation of sensory perception of pain|cardiac muscle cell differentiation|transmembrane transport|neuron death|cellular response to hypoxia|positive regulation of intracellular signal transduction|hydrogen ion transmembrane transport|,calmodulin binding|antiporter activity|solute:proton antiporter activity|sodium:proton antiporter activity|sodium:proton antiporter activity|sodium:proton antiporter activity|calcium-dependent protein binding|,10,-0.8,0.38,10,-0.7,0.255,-0.7,0.547,-0.547,0.614,0,0,-2,0.5
ENSMUSG00000031620,1700007B14RIK,RIKEN cDNA 1700007B14 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.48,10,0.6,0.14,0.1,0.542,0.542,0.615,0,0,-0.9,1.9
ENSMUSG00000033416,GUCD1,guanylyl cyclase domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.2,1.16,10,0,0,0.1,0.539,0.539,0.616,0,0,-1.3,1.6
ENSMUSG00000047617,BC029214,cDNA sequence BC029214,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.2,1.21,10,0,0,0.2,0.537,0.537,0.617,0,0,-1.1,1.6
ENSMUSG00000025731,0610011F06RIK,RIKEN cDNA 0610011F06 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,1.45,0.1,0.535,0.535,0.617,0,0,-1,1.8
ENSMUSG00000061689,DLGAP4,"discs, large homolog-associated protein 4 (Drosophila)",plasma membrane|membrane|dendrite|neuronal cell body|synapse|,cell-cell signaling|biological_process|,protein binding|protein domain specific binding|,10,0.2,0.814,10,0,0,0.1,0.532,0.532,0.618,0,0,-1.2,1.6
ENSMUSG00000051435,FHAD1,forkhead-associated (FHA) phosphopeptide binding domain 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.383,10,-0.1,0.195,-0.1,0.528,-0.528,0.619,0,0,-1.9,0.8
ENSMUSG00000042492,TBC1D10B,"TBC1 domain family, member 10b",cellular_component|cytoplasm|,regulation of Rab GTPase activity|positive regulation of Rab GTPase activity|,GTPase activator activity|Rab GTPase activator activity|,8,0.1,0.0426,9,0.7,1.25,0.1,0.521,0.521,0.621,0,0,-0.8,2
ENSMUSG00000041540,SOX5,SRY (sex determining region Y)-box 5,nucleus|nuclear transcription factor complex|,"in utero embryonic development|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|central nervous system neuron differentiation|positive regulation of chondrocyte differentiation|positive regulation of chondrocyte differentiation|cell fate commitment|negative regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|oligodendrocyte differentiation|cartilage development|regulation of timing of neuron differentiation|positive regulation of cartilage development|cellular response to transforming growth factor beta stimulus|positive regulation of mesenchymal stem cell differentiation|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|protein binding|transcription regulatory region DNA binding|protein heterodimerization activity|protein heterodimerization activity|,9,0.2,0.872,9,-0.2,0.408,0.2,0.521,0.521,0.621,0,0,-1.2,1.7
ENSMUSG00000072964,BHLHB9,"basic helix-loop-helix domain containing, class B9",nucleus|cytoplasm|extracellular vesicular exosome|,learning or memory|negative regulation of neuron apoptotic process|positive regulation of neurogenesis|positive regulation of synapse assembly|positive regulation of dendritic spine morphogenesis|,protein homodimerization activity|,10,0.2,1.31,10,0,0,0.1,0.521,0.521,0.621,0,0,-1.1,1.7
ENSMUSG00000044703,PHF11A,PHD finger protein 11A,cellular_component|nucleus|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.421,10,0.2,0.58,0.2,0.521,0.521,0.621,0,0,-1.1,1.6
ENSMUSG00000041035,DPCD,deleted in primary ciliary dyskinesia,nucleus|,epithelial cilium movement|spermatogenesis|determination of left/right symmetry|ventricular system development|lateral ventricle development|third ventricle development|sperm motility|left/right pattern formation|,molecular_function|,10,-0.2,1.29,10,0.2,0.252,-0.1,0.51,-0.51,0.625,0,0,-1.9,0.9
ENSMUSG00000037325,BBS7,Bardet-Biedl syndrome 7 (human),nucleus|cytoplasm|centrosome|centrosome|cytoskeleton|plasma membrane|cilium|axoneme|membrane|BBSome|BBSome|ciliary basal body|ciliary basal body|cell projection|,eye development|regulation of transcription from RNA polymerase II promoter|transport|smoothened signaling pathway|brain development|heart development|protein localization|protein transport|cell projection organization|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|nonmotile primary cilium assembly|palate development|limb development|,RNA polymerase II repressing transcription factor binding|,10,-0.1,0.366,10,-0.2,0.271,-0.2,0.502,-0.502,0.627,0,0,-1.5,1.2
ENSMUSG00000074884,SERF2,small EDRK-rich factor 2,cellular_component|,biological_process|,molecular_function|,9,-0.9,1.41,9,-0.1,0.14,-0.1,0.5,-0.5,0.627,0,0,-2,0.5
ENSMUSG00000079679,VWDE,von Willebrand factor D and EGF domains,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0.3,2.31,0.3,0.497,0.497,0.628,0,0,-0.9,1.8
ENSMUSG00000027327,1700037H04RIK,RIKEN cDNA 1700037H04 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.435,10,0.1,0.243,0.1,0.491,0.491,0.63,0,0,-1.1,1.7
ENSMUSG00000034801,SOS2,son of sevenless homolog 2 (Drosophila),intracellular|,small GTPase mediated signal transduction|positive regulation of Ras GTPase activity|regulation of Rho protein signal transduction|positive regulation of GTPase activity|regulation of small GTPase mediated signal transduction|positive regulation of small GTPase mediated signal transduction|,DNA binding|guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|protein heterodimerization activity|,10,-0.2,0.549,10,0.2,0.995,-0.2,0.488,-0.488,0.631,0,0,-1.2,1.5
ENSMUSG00000025102,3110040N11RIK,RIKEN cDNA 3110040N11 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.548,10,0.1,0.139,-0.1,0.471,-0.471,0.636,0,0,-1.6,1.2
ENSMUSG00000030805,STX4A,syntaxin 4A (placental),cell|cytoplasm|trans-Golgi network|plasma membrane|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|SNARE complex|myelin sheath adaxonal region|sarcolemma|specific granule|lateral loop|perinuclear region of cytoplasm|extracellular vesicular exosome|,protein complex assembly|transport|neurotransmitter transport|intracellular protein transport|synaptic vesicle exocytosis|synaptic vesicle docking involved in exocytosis|vesicle-mediated transport|SNARE complex assembly|membrane fusion|,SNARE binding|SNARE binding|SNAP receptor activity|protein binding|Rab GTPase binding|spectrin binding|,10,0.3,1.29,10,0,0,0.2,0.467,0.467,0.637,0,0,-1.1,1.7
ENSMUSG00000034863,ANO8,anoctamin 8,intracellular|plasma membrane|membrane|integral component of membrane|,chloride transport|chloride transmembrane transport|,None,10,-0.2,1.1,10,0.2,0.949,0.1,0.457,0.457,0.641,0,0,-1.3,1.4
ENSMUSG00000024379,TSLP,thymic stromal lymphopoietin,extracellular region|extracellular space|,None,cytokine activity|,10,0.1,0.51,10,-0.1,0.0854,0.1,0.454,0.454,0.642,0,0,-1.1,1.7
ENSMUSG00000047767,ATG16L2,autophagy related 16-like 2 (S. cerevisiae),nucleus|cytoplasm|,transport|autophagy|protein transport|negative stranded viral RNA replication|,molecular_function|,10,0.1,0.243,10,-0.1,0.474,-0.1,0.449,-0.449,0.643,0,0,-1.2,1.6
ENSMUSG00000024261,SYT4,synaptotagmin IV,cell|synaptic vesicle|membrane|integral component of membrane|cell junction|dense core granule|cytoplasmic vesicle|neuron projection|synapse|perinuclear region of cytoplasm|,transport|exocytosis|neurotransmitter secretion|regulation of calcium ion-dependent exocytosis|negative regulation of vesicle fusion|negative regulation of calcium ion-dependent exocytosis|synaptic vesicle transport|,SNARE binding|phosphatidylserine binding|transporter activity|calcium ion binding|clathrin binding|metal ion binding|,10,-0.2,0.619,10,-0.1,0.086,-0.2,0.448,-0.448,0.643,0,0,-1.7,1
ENSMUSG00000063052,LRRC40,leucine rich repeat containing 40,membrane|,biological_process|,molecular_function|,10,0.2,1.08,10,-0.2,0.305,0.2,0.439,0.439,0.646,0,0,-1.3,1.5
ENSMUSG00000051730,METTL5,methyltransferase like 5,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|nucleic acid binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.2,0.994,10,0,0,-0.2,0.438,-0.438,0.647,0,0,-1.7,1
ENSMUSG00000049562,AP5B1,"adaptor-related protein complex 5, beta 1 subunit",lysosomal membrane|AP-type membrane coat adaptor complex|,transport|protein transport|endosomal transport|,molecular_function|,10,0.4,1.91,10,0,0,0.1,0.436,0.436,0.648,0,0,-0.9,1.8
ENSMUSG00000044636,CSRNP2,cysteine-serine-rich nuclear protein 2,nucleus|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|apoptotic process|negative regulation of phosphatase activity|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|phosphatase binding|sequence-specific DNA binding|,10,-0.1,0.287,10,0.1,0.421,0.2,0.427,0.427,0.65,0,0,-1.1,1.7
ENSMUSG00000028436,DCAF12,DDB1 and CUL4 associated factor 12,cytoplasm|centrosome|cytoskeleton|Cul4-RING E3 ubiquitin ligase complex|,biological_process|,molecular_function|,9,0.5,0.964,10,-0.2,0.63,-0.1,0.426,-0.426,0.65,0,0,-1,1.9
ENSMUSG00000053747,SOX14,SRY (sex determining region Y)-box 14,nucleus|nuclear transcription factor complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|visual perception|entrainment of circadian clock|regulation of neuron migration|",sequence-specific DNA binding RNA polymerase II transcription factor activity|DNA binding|chromatin binding|protein heterodimerization activity|,10,0.5,0.795,10,0.1,0.269,0.1,0.424,0.424,0.651,0,0,-0.9,1.9
ENSMUSG00000032977,FAM207A,"family with sequence similarity 207, member A",cellular_component|,biological_process|,molecular_function|,10,0.1,0.593,10,-0.1,0.147,0.1,0.422,0.422,0.652,0,0,-1.6,1.3
ENSMUSG00000030731,SYT3,synaptotagmin III,endosome|synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,transport|calcium ion-dependent exocytosis|positive regulation of vesicle fusion|response to calcium ion|,SNARE binding|phosphatidylserine binding|transporter activity|protein binding|calcium-dependent phospholipid binding|syntaxin binding|clathrin binding|identical protein binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,-0.2,0.681,10,-0.1,0.0184,-0.1,0.422,-0.422,0.652,0,0,-1.8,1
ENSMUSG00000022094,SLC39A14,"solute carrier family 39 (zinc transporter), member 14",endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|iron ion transport|zinc ion transport|cellular zinc ion homeostasis|ferrous iron transport|metal ion transport|iron ion transmembrane transport|transmembrane transport|zinc ion transmembrane transport|zinc ion transmembrane transport|zinc ion transmembrane import|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|zinc ion transmembrane transporter activity|ferrous iron transmembrane transporter activity|metal ion transmembrane transporter activity|,10,-0.2,0.178,10,-0.1,0.421,-0.1,0.419,-0.419,0.653,0,0,-1.7,1.1
ENSMUSG00000031144,SYP,synaptophysin,synaptic vesicle|synaptic vesicle|membrane|integral component of membrane|cell junction|integral component of synaptic vesicle membrane|integral component of synaptic vesicle membrane|synaptic vesicle membrane|cytoplasmic vesicle|presynaptic membrane|neuron projection|intracellular organelle|protein complex|neuron projection terminus|neuron projection terminus|synapse|presynaptic active zone|excitatory synapse|excitatory synapse|,transport|endocytosis|endocytosis|synaptic transmission|regulation of neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|regulation of short-term neuronal synaptic plasticity|cellular response to organic substance|regulation of opioid receptor signaling pathway|,transporter activity|protein binding|cholesterol binding|syntaxin-1 binding|protein domain specific binding|protein complex binding|SH2 domain binding|identical protein binding|,10,0.4,0.264,10,-0.2,0.672,-0.1,0.418,-0.418,0.653,0,0,-1.2,1.7
ENSMUSG00000047604,FRAT2,frequently rearranged in advanced T cell lymphomas 2,cellular_component|,Wnt signaling pathway|,molecular_function|,10,0,0,10,0.1,0.537,0.1,0.417,0.417,0.653,0,0,-0.8,1.9
ENSMUSG00000066152,SLC31A2,"solute carrier family 31, member 2",late endosome|membrane|integral component of membrane|recycling endosome|,transport|ion transport|cellular copper ion homeostasis|cellular copper ion homeostasis|regulation of copper ion transmembrane transport|,protein binding|,10,-0.4,1.67,10,0.3,1.05,0.3,0.416,0.416,0.654,0,0,-1.2,1.6
ENSMUSG00000031970,DBNDD1,dysbindin (dystrobrevin binding protein 1) domain containing 1,cellular_component|cytoplasm|,biological_process|,molecular_function|,9,0.4,1.04,9,0,0,0.5,0.414,0.414,0.655,0,0,-0.6,2
ENSMUSG00000056692,D17WSU92E,"DNA segment, Chr 17, Wayne State University 92, expressed",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0397,10,-0.2,0.43,-0.1,0.404,-0.404,0.658,0,0,-1.6,1.2
ENSMUSG00000027488,SNTA1,"syntrophin, acidic 1",intracellular|cytoplasm|cytoskeleton|plasma membrane|membrane|cell junction|neuromuscular junction|sarcolemma|sarcolemma|protein complex|postsynaptic membrane|,regulation of heart rate|regulation of vasoconstriction by circulating norepinephrine|neuromuscular junction development|regulation of ventricular cardiac muscle cell membrane repolarization|ventricular cardiac muscle cell action potential|negative regulation of peptidyl-cysteine S-nitrosylation|regulation of sodium ion transmembrane transport|,actin binding|protein binding|calmodulin binding|sodium channel regulator activity|PDZ domain binding|ion channel binding|ion channel binding|nitric-oxide synthase binding|ATPase binding|,10,-0.2,0.849,10,0.1,0.186,0.2,0.4,0.4,0.659,0,0,-1.2,1.6
ENSMUSG00000074766,ISM1,isthmin 1 homolog (zebrafish),extracellular region|,None,None,10,0.2,1.23,10,0,0,0.1,0.397,0.397,0.66,0,0,-0.9,1.8
ENSMUSG00000022415,SYNGR1,synaptogyrin 1,synaptic vesicle|membrane|integral component of membrane|cell junction|synaptic vesicle membrane|synapse|,protein targeting|regulation of long-term neuronal synaptic plasticity|regulation of short-term neuronal synaptic plasticity|,None,10,0,0,10,-0.7,1.42,-0.1,0.396,-0.396,0.661,0,0,-2,0.5
ENSMUSG00000047368,ABHD17B,abhydrolase domain containing 17B,extracellular region|membrane|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,0.1,0.565,0.1,0.386,0.386,0.664,0,0,-1.1,1.7
ENSMUSG00000004897,HDGF,hepatoma-derived growth factor,extracellular space|extracellular space|nucleus|nucleus|cytoplasm|transcriptional repressor complex|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|cellular process|protein localization to nucleus|positive regulation of transcription from RNA polymerase II promoter|",nucleotide binding|RNA polymerase II transcription corepressor activity|transcription corepressor binding|DNA binding|protein binding|growth factor activity|heparin binding|poly(A) RNA binding|,9,0.1,0.119,9,-0.1,0.347,-0.1,0.386,-0.386,0.664,0,0,-1.7,1.2
ENSMUSG00000040631,DOK4,docking protein 4,intracellular|,MAPK cascade|transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|intracellular signal transduction|,receptor signaling protein activity|insulin receptor binding|,10,-0.2,0.933,10,0.2,0.502,-0.1,0.385,-0.385,0.664,0,0,-1.6,1.3
ENSMUSG00000079666,1700015F17RIK,RIKEN cDNA 1700015F17 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,1.23,10,-0.1,0.123,0.1,0.383,0.383,0.665,0,0,-1.2,1.6
ENSMUSG00000057594,ARL16,ADP-ribosylation factor-like 16,cellular_component|,biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0.2,0.387,10,0.2,0.0308,0.2,0.383,0.383,0.665,0,0,-0.9,1.8
ENSMUSG00000020072,PBLD1,phenazine biosynthesis-like protein domain containing 1,cytoplasm|extracellular vesicular exosome|,biosynthetic process|negative regulation of epithelial cell migration|negative regulation of epithelial to mesenchymal transition|maintenance of gastrointestinal epithelium|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of epithelial cell proliferation|negative regulation of SMAD protein import into nucleus|negative regulation of pathway-restricted SMAD protein phosphorylation|,molecular_function|catalytic activity|carnitine racemase activity|isomerase activity|NADHX epimerase activity|NADPHX epimerase activity|,10,-0.3,0.379,10,-0.1,0.172,-0.1,0.381,-0.381,0.665,0,0,-1.6,1.2
ENSMUSG00000038010,CCDC138,coiled-coil domain containing 138,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,1.02,0.1,0.379,0.379,0.666,0,0,-1,1.8
ENSMUSG00000034584,EXPH5,exophilin 5,endosome|,keratinocyte development|intracellular protein transport|positive regulation of exocytosis|positive regulation of protein secretion|multivesicular body sorting pathway|,protein binding|Rab GTPase binding|,10,0.6,0.676,10,-0.3,1.86,-0.1,0.371,-0.371,0.669,0,0,-1,1.8
ENSMUSG00000047181,SAMD14,sterile alpha motif domain containing 14,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,1.21,0.1,0.37,0.37,0.669,0,0,-1.6,1.5
ENSMUSG00000051166,EML5,echinoderm microtubule associated protein like 5,cytoplasm|cytoskeleton|microtubule|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.4,1.17,10,0.1,0.143,-0.3,0.36,-0.36,0.673,0,0,-1.8,0.9
ENSMUSG00000040935,PADI6,"peptidyl arginine deiminase, type VI",nucleus|cytoplasm|intermediate filament cytoskeleton|,cellular protein modification process|cytoskeleton organization|cytoplasm organization|protein citrullination|cellular protein localization|regulation of translation by machinery localization|,protein-arginine deiminase activity|calcium ion binding|protein binding|hydrolase activity|,10,0.1,0.352,10,0.3,0.202,0.1,0.358,0.358,0.673,0,0,-0.9,1.9
ENSMUSG00000027313,CHAC1,"ChaC, cation transport regulator 1",cytoplasm|Golgi apparatus|trans-Golgi network|cytosol|,apoptotic process|response to unfolded protein|Notch signaling pathway|nervous system development|negative regulation of protein processing|neurogenesis|negative regulation of Notch signaling pathway|intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|,Notch binding|,10,0.1,0.165,10,0.1,0.224,0.1,0.355,0.355,0.674,0,0,-1.3,1.6
ENSMUSG00000031023,AKIP1,A kinase (PRKA) interacting protein 1,nucleus|perinuclear region of cytoplasm|,substrate adhesion-dependent cell spreading|,protein binding|,10,-0.2,0.514,10,0.3,1.45,0.2,0.349,0.349,0.676,0,0,-1.6,1.3
ENSMUSG00000042558,ADPRHL2,ADP-ribosylhydrolase like 2,nucleus|nucleus|cytoplasm|mitochondrion|,cellular response to superoxide|,molecular_function|poly(ADP-ribose) glycohydrolase activity|hydrolase activity|metal ion binding|,10,0,0,10,-0.2,0.616,-0.1,0.347,-0.347,0.677,0,0,-1.4,1.6
ENSMUSG00000032551,1110059G10RIK,RIKEN cDNA 1110059G10 gene,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.421,10,0.3,1.29,-0.3,0.346,-0.346,0.677,0,0,-1.8,1
ENSMUSG00000031434,MORC4,microrchidia 4,cellular_component|nucleus|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,0.3,2.19,10,0,0,0.2,0.346,0.346,0.677,0,0,-0.9,1.8
ENSMUSG00000069825,SPATA22,spermatogenesis associated 22,cellular_component|chromosome|,meiotic DNA repair synthesis|meiotic nuclear division|synapsis|gamete generation|fertilization|regulation of meiotic cell cycle|reproductive system development|,protein binding|,10,-0.6,2.49,10,0.1,0.293,-0.3,0.345,-0.345,0.678,0,0,-1.8,1
ENSMUSG00000029851,FAM115C,"family with sequence similarity 115, member C",cellular_component|,hematopoietic progenitor cell differentiation|,molecular_function|,10,0.2,0.478,10,0,0,0.1,0.343,0.343,0.678,0,0,-1.4,1.5
ENSMUSG00000023266,FRS3,fibroblast growth factor receptor substrate 3,membrane|,fibroblast growth factor receptor signaling pathway|,fibroblast growth factor receptor binding|insulin receptor binding|,10,0.4,1.9,10,-0.3,0.943,0.1,0.342,0.342,0.679,0,0,-1.1,1.7
ENSMUSG00000030259,RASSF8,Ras association (RalGDS/AF-6) domain family (N-terminal) member 8,None,signal transduction|,None,10,0,0,10,-0.2,1.01,-0.1,0.342,-0.342,0.679,0,0,-1.5,1.3
ENSMUSG00000029797,SSPO,SCO-spondin,extracellular region|cytoplasm|,cell adhesion|biological_process|,molecular_function|hormone activity|,10,-0.2,0.563,10,0.1,0.073,-0.2,0.341,-0.341,0.679,0,0,-1.4,1.3
ENSMUSG00000029049,MORN1,MORN repeat containing 1,cellular_component|,biological_process|,molecular_function|,10,0.3,1.11,10,-0.1,0.0675,0.2,0.334,0.334,0.682,0,0,-0.8,1.9
ENSMUSG00000005125,NDRG1,N-myc downstream regulated gene 1,nucleus|cytoplasm|cytoplasm|centrosome|cytoskeleton|microtubule|plasma membrane|cell-cell adherens junction|microtubule cytoskeleton|membrane|perinuclear region of cytoplasm|recycling endosome membrane|extracellular vesicular exosome|,peripheral nervous system myelin maintenance|mast cell activation|positive regulation of spindle checkpoint|,microtubule binding|Rab GTPase binding|gamma-tubulin binding|cadherin binding|,10,0.3,0.278,10,0.1,0.13,-0.1,0.33,-0.33,0.683,0,0,-1.1,1.7
ENSMUSG00000001062,VPS9D1,VPS9 domain containing 1,None,biological_process|,molecular_function|,10,0.2,1.12,10,0,0,0.1,0.328,0.328,0.684,0,0,-1.5,1.4
ENSMUSG00000002608,CCDC97,coiled-coil domain containing 97,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,1.25,0.1,0.325,0.325,0.685,0,0,-1.8,1.2
ENSMUSG00000046138,9930021J03RIK,RIKEN cDNA 9930021J03 gene,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.2,10,0.2,0.646,-0.2,0.324,-0.324,0.685,0,0,-1.5,1.2
ENSMUSG00000057103,CML1,camello-like 1,mitochondrial inner membrane|endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,gastrulation with mouth forming second|negative regulation of cell adhesion|multicellular organismal development|gastrulation|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0,0,10,0.3,1.64,0.2,0.322,0.322,0.686,0,0,-0.9,1.8
ENSMUSG00000033006,SOX10,SRY (sex determining region Y)-box 10,nucleus|nucleus|cytoplasm|cytoplasm|extrinsic component of mitochondrial outer membrane|,"in utero embryonic development|neural crest cell migration|positive regulation of neuroblast proliferation|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|peripheral nervous system development|positive regulation of gliogenesis|cell differentiation|melanocyte differentiation|negative regulation of apoptotic process|negative regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cell maturation|cell maturation|enteric nervous system development|digestive tract morphogenesis|digestive tract morphogenesis|developmental growth|oligodendrocyte differentiation|negative regulation of canonical Wnt signaling pathway|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|DNA binding|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|protein binding|transcription factor binding|identical protein binding|transcription regulatory region DNA binding|,10,0.3,1.88,10,-1,1.52,0.2,0.322,0.322,0.686,0,0,-2,1
ENSMUSG00000028701,LURAP1,leucine rich adaptor protein 1,cytoplasm|actomyosin|,positive regulation of cytokine production|cell migration|actomyosin structure organization|positive regulation of I-kappaB kinase/NF-kappaB signaling|,molecular_function|,10,0.8,0.893,10,-0.2,0.485,-0.1,0.322,-0.322,0.686,0,0,-0.9,2
ENSMUSG00000037217,SYN1,synapsin I,synaptonemal complex|cell|cytosol|synaptic vesicle|axon|dendrite|synaptic vesicle membrane|intracellular organelle|synapse|presynaptic active zone|,neurotransmitter secretion|neurotransmitter secretion|,protein binding|protein dimerization activity|calcium-dependent protein binding|,10,0,0,10,-0.7,1.15,-0.1,0.313,-0.313,0.689,0,0,-1.9,1.4
ENSMUSG00000033948,ZSWIM5,zinc finger SWIM-type containing 5,extracellular space|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,9,-0.1,0.0584,9,-0.1,0.282,-0.1,0.311,-0.311,0.69,0,0,-1.8,1.2
ENSMUSG00000022575,GSDMD,gasdermin D,cellular_component|,cellular response to extracellular stimulus|,molecular_function|,10,0.2,1.06,10,0,0,0.1,0.311,0.311,0.69,0,0,-1.6,1.4
ENSMUSG00000029281,SMR2,submaxillary gland androgen regulated protein 2,extracellular region|,response to toxic substance|,None,10,-0.2,0.792,10,0.1,0.131,-0.1,0.301,-0.301,0.693,0,0,-1.7,1.1
ENSMUSG00000074513,ARFIP1,ADP-ribosylation factor interacting protein 1,Golgi membrane|cytosol|,intracellular protein transport|regulation of protein secretion|,identical protein binding|,10,0,0,10,0.1,0.401,0.1,0.3,0.3,0.694,0,0,-1.5,1.5
ENSMUSG00000090697,NSUN4,"NOL1/NOP2/Sun domain family, member 4",cytoplasm|mitochondrion|mitochondrial large ribosomal subunit|,rRNA processing|biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.3,0.945,10,-0.1,0.0121,-0.2,0.296,-0.296,0.695,0,0,-1.2,1.5
ENSMUSG00000040250,ASUN,"asunder, spermatogenesis regulator",cytoplasm|cytoplasm|,cell cycle|mitotic spindle organization|mitotic nuclear division|regulation of mitotic cell cycle|cell division|centrosome localization|protein localization to nuclear envelope|,molecular_function|,10,0.7,0.198,10,-0.3,0.747,0.1,0.294,0.294,0.696,0,0,-1,1.9
ENSMUSG00000074748,ATXN7L3B,ataxin 7-like 3B,cellular_component|,biological_process|,molecular_function|,9,-0.1,0.33,9,0,0,-0.1,0.291,-0.291,0.697,0,0,-1.8,1.2
ENSMUSG00000094881,GM6026,predicted gene 6026,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.947,10,0,0,-0.1,0.289,-0.289,0.698,0,0,-1.7,1.1
ENSMUSG00000040794,C1QTNF4,C1q and tumor necrosis factor related protein 4,cellular_component|extracellular region|extracellular space|,biological_process|,molecular_function|cytokine activity|,10,0.2,1.08,10,0,0,0.1,0.287,0.287,0.699,0,0,-1.2,1.7
ENSMUSG00000079144,A130010J15RIK,RIKEN cDNA A130010J15 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.85,10,0,0,-0.1,0.286,-0.286,0.699,0,0,-1.5,1.4
ENSMUSG00000037773,PCED1A,PC-esterase domain containing 1A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,1.95,-0.1,0.278,-0.278,0.702,0,0,-1,1.8
ENSMUSG00000078185,CHML,choroideremia-like,cytoplasm|Rab-protein geranylgeranyltransferase complex|,intracellular protein transport|protein geranylgeranylation|,Rab geranylgeranyltransferase activity|GTPase activator activity|Rab GTPase binding|,10,0.2,0.353,10,0.1,0.109,0.1,0.274,0.274,0.703,0,0,-1.2,1.7
ENSMUSG00000018809,SMYD4,SET and MYND domain containing 4,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|metal ion binding|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0,0,10,-0.2,0.387,-0.1,0.274,-0.274,0.703,0,0,-1.3,1.6
ENSMUSG00000043505,GIMAP5,"GTPase, IMAP family member 5",mitochondrion|mitochondrial outer membrane|lysosome|membrane|integral component of membrane|,None,nucleotide binding|GTP binding|,10,-0.1,0.526,10,0,0,-0.1,0.274,-0.274,0.703,0,0,-1.8,1.1
ENSMUSG00000028582,CC2D1B,coiled-coil and C2 domain containing 1B,nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|,10,-0.2,0.457,10,0.3,0.685,-0.1,0.268,-0.268,0.705,0,0,-1.4,1.4
ENSMUSG00000044148,1810030O07RIK,RIKEN cDNA 1810030O07 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.533,0.2,0.267,0.267,0.706,0,0,-1.2,1.6
ENSMUSG00000054266,SERPINB9D,"serine (or cysteine) peptidase inhibitor, clade B, member 9d",cytoplasm|,negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|,10,0,0,10,-0.5,1.93,-0.1,0.266,-0.266,0.706,0,0,-1.9,0.8
ENSMUSG00000017316,PPY,pancreatic polypeptide,extracellular region|,None,G-protein coupled receptor binding|hormone activity|,10,0.1,0.398,10,0,0,0.1,0.266,0.266,0.706,0,0,-1.7,1.3
ENSMUSG00000038156,SPON1,"spondin 1, (f-spondin) extracellular matrix protein",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|,cell adhesion|,None,10,0,0,10,-0.2,0.439,-0.2,0.264,-0.264,0.707,0,0,-1.8,0.9
ENSMUSG00000024505,DTWD2,DTW domain containing 2,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.26,10,0.1,0.113,-0.2,0.261,-0.261,0.708,0,0,-1.1,1.8
ENSMUSG00000022236,ROPN1L,ropporin 1-like,cytoplasm|motile cilium|motile cilium|,regulation of protein phosphorylation|cilium movement|sperm motility|sperm capacitation|,molecular_function|,10,0,0,10,0.3,0.752,0.1,0.258,0.258,0.709,0,0,-1.7,1.4
ENSMUSG00000055874,FOXI3,forkhead box I3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|",DNA binding|,10,-0.1,0.506,10,0.3,1.55,0.1,0.255,0.255,0.71,0,0,-1,1.7
ENSMUSG00000020280,PUS10,pseudouridylate synthase 10,cellular_component|,pseudouridine synthesis|tRNA processing|biological_process|RNA modification|,molecular_function|RNA binding|pseudouridine synthase activity|isomerase activity|pivalyl-CoA mutase activity|o-hydroxylaminobenzoate mutase activity|lupeol synthase activity|beta-amyrin synthase activity|baruol synthase activity|,10,0.2,0.945,10,-0.1,0.369,0.1,0.254,0.254,0.711,0,0,-1.3,1.5
ENSMUSG00000026201,STK16,serine/threonine kinase 16,cytoplasm|Golgi-associated vesicle|membrane|,transcription from RNA polymerase II promoter|protein phosphorylation|phosphorylation|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|protein autophosphorylation|cellular response to transforming growth factor beta stimulus|,"nucleotide binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|protein kinase activity|protein serine/threonine kinase activity|non-membrane spanning protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,-0.1,0.521,10,0,0,-0.1,0.252,-0.252,0.711,0,0,-1.7,1.3
ENSMUSG00000043230,FAM124B,"family with sequence similarity 124, member B",cellular_component|,biological_process|,molecular_function|,10,0.2,0.649,10,0,0,0.1,0.252,0.252,0.711,0,0,-1,1.8
ENSMUSG00000023911,FLYWCH2,FLYWCH family member 2,cellular_component|,biological_process|,poly(A) RNA binding|,10,0,0,10,0.4,1.74,0.1,0.252,0.252,0.711,0,0,-1.2,1.7
ENSMUSG00000039395,MREG,melanoregulin,plasma membrane|membrane|melanosome|protein complex|,melanocyte differentiation|melanosome transport|anagen|pigmentation|developmental pigmentation|,protein binding|,10,-0.2,0.371,10,0.5,0.112,-0.1,0.247,-0.247,0.713,0,0,-1.7,1.3
ENSMUSG00000074527,GM14296,predicted gene 14296,None,None,None,4,-0.8,1.87,4,0,0,-0.7,0.246,-0.246,0.714,0,0,-2,1.2
ENSMUSG00000073599,ECSCR,endothelial cell surface expressed chemotaxis and apoptosis regulator,cytoplasm|plasma membrane|membrane|integral component of membrane|,angiogenesis|apoptotic process|chemotaxis|multicellular organismal development|cell differentiation|,None,10,-0.6,1.75,10,0,0,-0.1,0.246,-0.246,0.714,0,0,-1.9,0.9
ENSMUSG00000078798,SULT2A1,"sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1",cytoplasm|cytosol|,lipid metabolic process|steroid metabolic process|,alcohol sulfotransferase activity|drug binding|sulfotransferase activity|transferase activity|bile-salt sulfotransferase activity|3'-phosphoadenosine 5'-phosphosulfate binding|,10,0.1,0.563,10,-0.4,1.21,0.1,0.244,0.244,0.714,0,0,-1.8,1.1
ENSMUSG00000026594,RALGPS2,Ral GEF with PH domain and SH3 binding motif 2,cellular_component|cytoplasm|plasma membrane|membrane|,small GTPase mediated signal transduction|biological_process|,molecular_function|guanyl-nucleotide exchange factor activity|,10,0,0,10,0.2,0.517,0.1,0.237,0.237,0.717,0,0,-1.3,1.5
ENSMUSG00000040242,FGFR1OP2,FGFR1 oncogene partner 2,cytoplasm|,wound healing|,protein homodimerization activity|,9,0.2,0.871,9,0,0,0.1,0.231,0.231,0.719,0,0,-1.2,1.7
ENSMUSG00000039242,B3GALNT2,"UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,protein glycosylation|protein O-linked glycosylation|UDP-N-acetylgalactosamine metabolic process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.2,1.66,10,0,0,0.1,0.224,0.224,0.722,0,0,-1.1,1.7
ENSMUSG00000002768,MEA1,male enhanced antigen 1,cytoplasm|,multicellular organismal development|spermatogenesis|cell differentiation|,None,10,0.2,1.01,10,0,0,0.1,0.223,0.223,0.722,0,0,-1.1,1.8
ENSMUSG00000039307,HEXDC,"hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing",nucleus|cytoplasm|,carbohydrate metabolic process|metabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-N-acetylhexosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.2,0.831,10,0,0,0.1,0.221,0.221,0.723,0,0,-1.1,1.8
ENSMUSG00000027550,LRRCC1,leucine rich repeat and coiled-coil domain containing 1,nucleus|cytoplasm|centrosome|cytoskeleton|,cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,10,-0.6,1.41,10,0.2,0.686,0.1,0.217,0.217,0.724,0,0,-1.8,1
ENSMUSG00000036655,COLEC11,collectin sub-family member 11,cellular_component|extracellular region|collagen trimer|,multicellular organismal development|biological_process|,mannose binding|carbohydrate binding|,8,0.2,0.0644,9,0.2,0.163,0.2,0.207,0.207,0.728,0,0,-1.1,1.9
ENSMUSG00000025060,SLK,STE20-like kinase,cytoplasm|extracellular vesicular exosome|,protein phosphorylation|protein phosphorylation|apoptotic process|phosphorylation|signal transduction by phosphorylation|protein autophosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|identical protein binding|protein homodimerization activity|",10,-0.3,1.06,10,0,0,-0.1,0.207,-0.207,0.728,0,0,-1.2,1.7
ENSMUSG00000061397,KRT79,keratin 79,intermediate filament|keratin filament|extracellular vesicular exosome|,None,structural molecule activity|enzyme binding|,10,0.3,1.39,10,-0.4,1.55,-0.2,0.203,-0.203,0.73,0,0,-1.5,1.4
ENSMUSG00000096014,SOX1,SRY (sex determining region Y)-box 1,nucleus|,"neuron migration|lens morphogenesis in camera-type eye|transcription, DNA-templated|regulation of transcription, DNA-templated|ventral spinal cord interneuron specification|forebrain neuron differentiation|forebrain neuron development|forebrain development|",core promoter sequence-specific DNA binding|DNA binding|sequence-specific DNA binding|,10,0,0,10,0.1,0.643,0.1,0.203,0.203,0.73,0,0,-1.2,1.7
ENSMUSG00000051000,FAM160A1,"family with sequence similarity 160, member A1",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.558,10,0,0,-0.1,0.193,-0.193,0.734,0,0,-1.7,1.1
ENSMUSG00000057554,LGALS8,"lectin, galactose binding, soluble 8",cytoplasm|membrane|extracellular vesicular exosome|,plasma cell differentiation|T cell costimulation|,carbohydrate binding|,10,0.3,0.356,10,0,0,0.1,0.193,0.193,0.734,0,0,-1.1,1.7
ENSMUSG00000026502,DESI2,desumoylating isopeptidase 2,cytoplasm|,proteolysis|biological_process|,molecular_function|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.2,1.54,10,-0.2,0.709,0.2,0.192,0.192,0.734,0,0,-1.3,1.5
ENSMUSG00000001076,C1QL4,"complement component 1, q subcomponent-like 4",extracellular region|collagen trimer|extracellular space|,negative regulation of fat cell differentiation|negative regulation of fibroblast proliferation|negative regulation of ERK1 and ERK2 cascade|,protein binding|identical protein binding|,10,-0.1,0.212,10,0,0,-0.1,0.192,-0.192,0.734,0,0,-1.7,1.2
ENSMUSG00000056832,TTC26,tetratricopeptide repeat domain 26,intracellular|cell|centrosome|cilium|cilium|cilium|intraciliary transport particle B|ciliary basal body|cell projection|primary cilium|,photoreceptor cell morphogenesis|cell projection organization|intraciliary transport|cilium assembly|cilium assembly|photoreceptor cell differentiation|,molecular_function|,10,0.1,0.364,10,-0.2,0.941,-0.1,0.19,-0.19,0.735,0,0,-1.5,1.3
ENSMUSG00000068245,PHF11D,PHD finger protein 11D,cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|zinc ion binding|metal ion binding|,10,0.2,1.34,10,0,0,0.1,0.18,0.18,0.739,0,0,-1,1.8
ENSMUSG00000027954,EFNA1,ephrin A1,extracellular region|plasma membrane|membrane|anchored component of membrane|anchored component of plasma membrane|extracellular vesicular exosome|,negative regulation of transcription from RNA polymerase II promoter|activation of MAPK activity|angiogenesis|aortic valve morphogenesis|mitral valve morphogenesis|endocardial cushion to mesenchymal transition involved in heart valve formation|axon guidance|negative regulation of epithelial to mesenchymal transition|notochord formation|cell migration|neuron differentiation|regulation of cell adhesion mediated by integrin|substrate adhesion-dependent cell spreading|regulation of blood vessel endothelial cell migration|regulation of angiogenesis|ephrin receptor signaling pathway|ephrin receptor signaling pathway|regulation of peptidyl-tyrosine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|regulation of axonogenesis|negative regulation of dendritic spine morphogenesis|,protein binding|ephrin receptor binding|ephrin receptor binding|,10,-0.1,0.502,10,0,0,-0.1,0.179,-0.179,0.739,0,0,-1.8,1.1
ENSMUSG00000044072,EML6,echinoderm microtubule associated protein like 6,cellular_component|cytoplasm|cytoskeleton|microtubule|,biological_process|,molecular_function|,9,-0.3,1.54,9,0,0,0.1,0.178,0.178,0.74,0,0,-1.5,1.4
ENSMUSG00000039760,IL22RA2,"interleukin 22 receptor, alpha 2",extracellular region|cytosol|,cytokine-mediated signaling pathway|regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of inflammatory response|,protein binding|interleukin-22 binding|interleukin-22 receptor activity|,10,0.3,1.1,10,0,0,0.1,0.177,0.177,0.74,0,0,-1.3,1.7
ENSMUSG00000036501,FAM13B,"family with sequence similarity 13, member B",intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,-0.1,0.28,10,0,0,-0.1,0.175,-0.175,0.741,0,0,-1.6,1.3
ENSMUSG00000027639,SAMHD1,"SAM domain and HD domain, 1",nucleus|plasma membrane|,immune system process|dGTP catabolic process|metabolic process|innate immune response|regulation of innate immune response|dATP catabolic process|protein homotetramerization|defense response to virus|,nucleic acid binding|RNA binding|catalytic activity|zinc ion binding|dGTPase activity|hydrolase activity|dGTP binding|metal ion binding|,10,-0.1,0.0405,10,-0.2,0.218,-0.1,0.172,-0.172,0.742,0,0,-1.8,1.1
ENSMUSG00000021578,CCDC127,coiled-coil domain containing 127,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.4,1.18,0.2,0.172,0.172,0.742,0,0,-0.7,1.9
ENSMUSG00000033965,SLC16A2,"solute carrier family 16 (monocarboxylic acid transporters), member 2",plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|hormone transport|transmembrane transport|thyroid hormone transport|,symporter activity|thyroid hormone transmembrane transporter activity|,10,0.8,2.12,10,0,0,0.1,0.169,0.169,0.743,0,0,-0.5,2
ENSMUSG00000044117,2900011O08RIK,RIKEN cDNA 2900011O08 gene,cellular_component|,biological_process|,protein binding|,10,0,0,10,-0.2,0.554,-0.1,0.168,-0.168,0.743,0,0,-1.5,1.4
ENSMUSG00000042050,WDR60,WD repeat domain 60,extracellular space|cilium|cell projection|extracellular vesicular exosome|,biological_process|cell projection organization|,molecular_function|,10,0,0,10,-0.2,0.316,-0.1,0.165,-0.165,0.745,0,0,-1.9,0.8
ENSMUSG00000072812,AHNAK2,AHNAK nucleoprotein 2,cytoplasm|plasma membrane|virion|viral nucleocapsid|Z disc|T-tubule|cytoplasmic vesicle membrane|costamere|,None,molecular_function|,10,0,0,10,-0.2,0.541,-0.1,0.164,-0.164,0.745,0,0,-1.9,1
ENSMUSG00000030827,FGF21,fibroblast growth factor 21,extracellular region|,positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|positive regulation of glucose import|positive regulation of ERK1 and ERK2 cascade|positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway|,receptor binding|fibroblast growth factor receptor binding|growth factor activity|,10,0,0,10,0.2,0.239,0.1,0.161,0.161,0.746,0,0,-1.1,1.7
ENSMUSG00000059834,SCLT1,sodium channel and clathrin linker 1,cytoplasm|centrosome|centriole|centriole|cytoskeleton|microtubule cytoskeleton|extracellular vesicular exosome|clathrin complex|ciliary transition fiber|,cilium assembly|clustering of voltage-gated sodium channels|,protein C-terminus binding|sodium channel regulator activity|clathrin binding|,10,0.1,0.0372,10,0.1,0.126,0.1,0.149,0.149,0.75,0,0,-1.3,1.7
ENSMUSG00000030556,LRRC28,leucine rich repeat containing 28,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.774,-0.1,0.142,-0.142,0.753,0,0,-1.8,1.1
ENSMUSG00000022948,SETD4,SET domain containing 4,cellular_component|,biological_process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.3,1.02,10,-0.4,0.854,0.2,0.133,0.133,0.757,0,0,-1.5,1.4
ENSMUSG00000027273,SNAP25,synaptosomal-associated protein 25,cell|cytoplasm|cytoplasm|endosome|trans-Golgi network|cytosol|plasma membrane|plasma membrane|voltage-gated potassium channel complex|actin cytoskeleton|membrane|lamellipodium|cell junction|filopodium|axon|growth cone|BLOC-1 complex|SNARE complex|neuron projection|neuronal cell body|intracellular organelle|axonal growth cone|membrane raft|synapse|perinuclear region of cytoplasm|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex|synaptobrevin 2-SNAP-25-syntaxin-1a complex|,neurotransmitter secretion|long-term memory|regulation of neuron projection development|endosomal transport|sleep|regulation of ion transmembrane transport|positive regulation of hormone secretion|calcium ion-dependent exocytosis of neurotransmitter|long-term synaptic potentiation|regulation of establishment of protein localization|potassium ion transmembrane transport|,SNARE binding|SNARE binding|voltage-gated potassium channel activity|protein binding|myosin binding|syntaxin-1 binding|protein domain specific binding|protein N-terminus binding|,10,0.3,0.804,10,0,0,0.1,0.132,0.132,0.757,0,0,-0.9,1.9
ENSMUSG00000047963,STBD1,starch binding domain 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|carbohydrate binding|starch binding|,10,-0.1,0.158,10,0,0,-0.1,0.124,-0.124,0.761,0,0,-1.5,1.5
ENSMUSG00000052407,CCDC171,coiled-coil domain containing 171,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.43,10,0,0,-0.1,0.124,-0.124,0.761,0,0,-1.8,1.1
ENSMUSG00000030177,CCDC77,coiled-coil domain containing 77,centrosome|membrane|,biological_process|,molecular_function|,10,0.5,1.53,10,0,0,0.1,0.121,0.121,0.762,0,0,-0.6,2
ENSMUSG00000046719,NXPH3,neurexophilin 3,extracellular region|,None,receptor binding|,10,0.1,0.543,10,0,0,0.1,0.121,0.121,0.762,0,0,-1.3,1.7
ENSMUSG00000050423,PPP1R3G,"protein phosphatase 1, regulatory (inhibitor) subunit 3G",cytoplasm|,glucose homeostasis|glucose homeostasis|positive regulation of glycogen biosynthetic process|positive regulation of glycogen biosynthetic process|positive regulation of glycogen (starch) synthase activity|positive regulation of glycogen (starch) synthase activity|,protein phosphatase binding|glycogen binding|,10,0.2,0.895,10,0,0,0.1,0.118,0.118,0.763,0,0,-1,1.8
ENSMUSG00000028373,ASTN2,astrotactin 2,endosome|membrane|integral component of membrane|cell pole|,negative regulation of protein localization to cell surface|,protein binding|,10,-0.2,0.35,10,0,0,-0.1,0.115,-0.115,0.764,0,0,-1.7,1.1
ENSMUSG00000041915,AMMECR1L,AMME chromosomal region gene 1-like,cellular_component|,biological_process|,molecular_function|,10,0.1,0.334,10,-1.1,1.09,0.1,0.114,0.114,0.764,0,0,-2,1
ENSMUSG00000028885,SMPDL3B,"sphingomyelin phosphodiesterase, acid-like 3B",extracellular region|extracellular space|extracellular vesicular exosome|,sphingomyelin catabolic process|biological_process|metabolic process|,"molecular_function|cyclic-nucleotide phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activity|calmodulin-dependent cyclic-nucleotide phosphodiesterase activity|cGMP-stimulated cyclic-nucleotide phosphodiesterase activity|cGMP-inhibited cyclic-nucleotide phosphodiesterase activity|photoreceptor cyclic-nucleotide phosphodiesterase activity|sphingomyelin phosphodiesterase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity|inositol phosphosphingolipid phospholipase activity|inositol phosphorylceramide phospholipase activity|mannosyl-inositol phosphorylceramide phospholipase activity|mannosyl-diinositol phosphorylceramide phospholipase activity|",10,-0.8,0.269,10,0.3,0.774,0.2,0.109,0.109,0.766,0,0,-1.8,1.3
ENSMUSG00000032593,AMIGO3,adhesion molecule with Ig like domain 3,membrane|integral component of membrane|,cell adhesion|heterophilic cell-cell adhesion|heterophilic cell-cell adhesion|nervous system development|,molecular_function|,10,0,0,10,-0.9,2.24,-0.1,0.104,-0.104,0.768,0,0,-2,0.5
ENSMUSG00000031357,SYAP1,synapse associated protein 1,nucleus|nucleus|cytoplasm|Golgi apparatus|,biological_process|,molecular_function|,10,0.7,0.159,10,0.1,0.319,0.1,0.102,0.102,0.769,0,0,-1.1,2
ENSMUSG00000030583,SIPA1L3,signal-induced proliferation-associated 1 like 3,extracellular space|,hematopoietic progenitor cell differentiation|,molecular_function|,9,0.2,0.663,9,0,0,0.1,0.0963,0.0963,0.771,0,0,-1.4,1.7
ENSMUSG00000074570,CASS4,Cas scaffolding protein family member 4,cytoplasm|cytoskeleton|cell junction|,cell adhesion|,None,10,0.2,0.937,10,0,0,0.1,0.0929,0.0929,0.772,0,0,-1.2,1.7
ENSMUSG00000042826,FGF11,fibroblast growth factor 11,extracellular region|nucleus|,None,receptor binding|growth factor activity|,10,0.2,0.614,10,-0.2,0.821,-0.1,0.0915,-0.0915,0.773,0,0,-1.5,1.4
ENSMUSG00000028182,LRRIQ3,leucine-rich repeats and IQ motif containing 3,cellular_component|,biological_process|,molecular_function|,10,0.1,0.14,10,0,0,0.1,0.0898,0.0898,0.774,0,0,-1.7,1.3
ENSMUSG00000039414,HEATR5B,HEAT repeat containing 5B,membrane|extracellular vesicular exosome|,biological_process|,protein binding|,10,0.4,1.33,10,0,0,0.1,0.0869,0.0869,0.775,0,0,-0.7,2
ENSMUSG00000015850,ADAMTSL4,ADAMTS-like 4,extracellular region|proteinaceous extracellular matrix|interstitial matrix|extracellular matrix|,apoptotic process|extracellular matrix organization|positive regulation of apoptotic process|,protease binding|metalloendopeptidase activity|peptidase activity|,10,-0.9,0.788,10,0.1,0.156,-0.1,0.0799,-0.0799,0.777,0,0,-2,0.9
ENSMUSG00000015790,SURF1,surfeit gene 1,mitochondrion|mitochondrial inner membrane|membrane|integral component of membrane|,oxidative phosphorylation|ATP biosynthetic process|oxidation-reduction process|hydrogen ion transmembrane transport|,cytochrome-c oxidase activity|,10,0.2,0.693,10,0,0,0.1,0.0762,0.0762,0.779,0,0,-1.2,1.7
ENSMUSG00000045237,1110012L19RIK,RIKEN cDNA 1110012L19 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.841,10,0.2,0.383,-0.1,0.0735,-0.0735,0.78,0,0,-1.3,1.5
ENSMUSG00000095440,FIGNL2,fidgetin-like 2,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,-0.4,1.64,10,0,0,-0.2,0.0688,-0.0688,0.782,0,0,-1.9,0.8
ENSMUSG00000058192,ZFP846,zinc finger protein 846,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.8,2.57,10,-0.1,0.141,0.2,0.0674,0.0674,0.782,0,0,-0.8,2
ENSMUSG00000078960,TOB2,"transducer of ERBB2, 2",None,regulation of gene expression|negative regulation of osteoclast differentiation|positive regulation of ossification|,vitamin D receptor binding|,10,0.3,0.708,10,-0.1,0.0249,-0.1,0.0656,-0.0656,0.783,0,0,-1.3,1.6
ENSMUSG00000071230,NPW,neuropeptide W,cellular_component|,G-protein coupled receptor signaling pathway|feeding behavior|,G-protein coupled receptor binding|,10,0.1,0.509,10,0,0,0.1,0.0616,0.0616,0.785,0,0,-1.2,1.7
ENSMUSG00000020564,ATXN7L1,ataxin 7-like 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.207,10,0,0,-0.1,0.061,-0.061,0.785,0,0,-1.6,1.2
ENSMUSG00000028332,HEMGN,hemogen,nucleus|nucleoplasm|,multicellular organismal development|cell differentiation|regulation of osteoblast differentiation|,molecular_function|,9,0.2,0.743,9,0,0,0.1,0.061,0.061,0.785,0,0,-1.2,1.8
ENSMUSG00000095390,OLFR229,olfactory receptor 229,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.298,10,0.5,1.77,-0.1,0.0583,-0.0583,0.786,0,0,-1,1.9
ENSMUSG00000048924,CCDC125,coiled-coil domain containing 125,cytoplasm|,biological_process|,molecular_function|,10,0.3,0.189,10,-0.5,1.78,-0.1,0.0545,-0.0545,0.787,0,0,-1.8,1.1
ENSMUSG00000006763,SAAL1,serum amyloid A-like 1,cellular_component|collagen trimer|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.281,-0.1,0.0539,-0.0539,0.788,0,0,-1.9,0.9
ENSMUSG00000074345,TNFAIP8L3,"tumor necrosis factor, alpha-induced protein 8-like 3",cellular_component|,biological_process|,molecular_function|,10,0.1,0.628,10,-0.1,0.0222,0.1,0.0456,0.0456,0.791,0,0,-1.5,1.5
ENSMUSG00000028451,1700022I11RIK,RIKEN cDNA 1700022I11 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.00515,10,-0.1,0.0438,-0.1,0.0445,-0.0445,0.791,0,0,-1.7,1.3
ENSMUSG00000040010,SLC7A5,"solute carrier family 7 (cationic amino acid transporter, y+ system), member 5",nucleus|nucleolus|cytoplasm|plasma membrane|membrane|membrane|integral component of membrane|extracellular vesicular exosome|,amino acid transmembrane transport|transport|amino acid transport|multicellular organismal development|nervous system development|L-amino acid transport|cell differentiation|L-alpha-amino acid transmembrane transport|,amino acid transmembrane transporter activity|L-amino acid transmembrane transporter activity|,10,-0.9,0.315,9,-0.1,0.00233,-0.1,0.0419,-0.0419,0.792,0,0,-2,0.8
ENSMUSG00000038957,EDC3,enhancer of mRNA decapping 3 homolog (S. cerevisiae),cytoplasm|membrane|,biological_process|,RNA binding|identical protein binding|,10,-0.1,0.145,10,0,0,-0.1,0.041,-0.041,0.793,0,0,-1.5,1.4
ENSMUSG00000000167,PIH1D2,PIH1 domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.204,0.1,0.033,0.033,0.796,0,0,-1.4,1.6
ENSMUSG00000016344,PPDPF,pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)RIKEN cDNA 2700038C09 gene,cellular_component|,multicellular organismal development|biological_process|cell differentiation|,molecular_function|,9,-0.1,0.179,9,0,0,-0.1,0.026,-0.026,0.799,0,0,-2,1
ENSMUSG00000063145,BBS5,Bardet-Biedl syndrome 5 (human),intracellular|cytoplasm|cytoskeleton|plasma membrane|cilium|membrane|BBSome|BBSome|ciliary basal body|ciliary basal body|cell projection|,transport|protein transport|cell projection organization|cilium assembly|,RNA polymerase II repressing transcription factor binding|phosphatidylinositol-3-phosphate binding|,10,0,0,10,-0.2,0.394,-0.1,0.0209,-0.0209,0.8,0,0,-1.8,1
ENSMUSG00000002635,PDCD2L,programmed cell death 2-like,cytoplasm|membrane|,cell cycle|biological_process|,molecular_function|,10,0.2,0.771,10,-0.1,0.062,0.1,0.0193,0.0193,0.801,0,0,-1.6,1.3
ENSMUSG00000047528,ALS2CR12,"amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12 (human)",outer dense fiber|cytoplasm|sperm fibrous sheath|sperm flagellum|,biological_process|,molecular_function|,10,-0.2,1.04,10,0,0,-0.1,0.0187,-0.0187,0.801,0,0,-1,2
ENSMUSG00000017764,ZSWIM1,zinc finger SWIM-type containing 1,nucleus|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.3,0.896,10,0.6,0.609,0.1,0.0178,0.0178,0.802,0,0,-1.1,1.9
ENSMUSG00000038836,AGBL3,ATP/GTP binding protein-like 3,cellular_component|cytoplasm|,proteolysis|,carboxypeptidase activity|metallocarboxypeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0,0,10,0.1,0.335,0.1,0.0171,0.0171,0.802,0,0,-1.1,1.8
ENSMUSG00000045004,SPATA21,spermatogenesis associated 21,cellular_component|,biological_process|,molecular_function|calcium ion binding|metal ion binding|,10,-1.1,2.06,10,0.1,0.146,0.1,0.0142,0.0142,0.803,0,0,-2,0.9
ENSMUSG00000069793,SLFN9,schlafen 9,intracellular|nucleus|,biological_process|,molecular_function|,10,0.1,0.745,10,-0.1,0.0989,0.1,0.0142,0.0142,0.803,0,0,-1.5,1.5
ENSMUSG00000033419,SNAP91,synaptosomal-associated protein 91,cell|plasma membrane|coated pit|synaptic vesicle|postsynaptic density|membrane|clathrin coat|AP-2 adaptor complex|presynaptic membrane|postsynaptic membrane|,transport|establishment or maintenance of cell polarity|synaptic transmission|neurotransmitter secretion|axonogenesis|protein transport|regulation of endocytosis|clathrin coat assembly|clathrin coat assembly|regulation of protein transport|,protein binding|phospholipid binding|1-phosphatidylinositol binding|clathrin binding|clathrin heavy chain binding|,10,0.1,0.17,10,0,0,0.1,0.0123,0.0123,0.804,0,0,-1.3,1.6
ENSMUSG00000040263,KLHDC4,kelch domain containing 4,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.25,-0.1,0.0123,-0.0123,0.804,0,0,-2,1.1
ENSMUSG00000037014,SSTR4,somatostatin receptor 4,cytoplasm|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|cell migration|arachidonic acid metabolic process|negative regulation of cAMP metabolic process|somatostatin signaling pathway|positive regulation of MAPK cascade|,signal transducer activity|G-protein coupled receptor activity|somatostatin receptor activity|protein binding|,10,-0.1,0.149,10,0,0,-0.1,0.0103,-0.0103,0.805,0,0,-1.8,1.1
ENSMUSG00000022002,4930564B18RIK,RIKEN cDNA 4930564B18 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,0.947,10,-0.2,0.468,0.1,0.00902,0.00902,0.805,0,0,-1.1,1.7
ENSMUSG00000033594,SPATA2L,spermatogenesis associated 2-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.505,0.1,0.00834,0.00834,0.805,0,0,-1.4,1.6
ENSMUSG00000055485,SOGA1,"suppressor of glucose, autophagy associated 1",extracellular region|extracellular space|extracellular space|extracellular vesicular exosome|,insulin receptor signaling pathway|regulation of autophagy|negative regulation of gluconeogenesis|,molecular_function|,10,0.3,1.4,10,0,0,0.1,0.00685,0.00685,0.806,0,0,-1.2,1.7
ENSMUSG00000029192,TBC1D14,"TBC1 domain family, member 14",autophagic vacuole|Golgi apparatus|,negative regulation of autophagy|regulation of Rab GTPase activity|regulation of autophagic vacuole assembly|,GTPase activator activity|Rab GTPase activator activity|protein kinase binding|,10,-0.2,0.43,10,0.1,0.415,-0.1,0.0057,-0.0057,0.806,0,0,-1.7,1.1
ENSMUSG00000035495,TSTD2,thiosulfate sulfurtransferase (rhodanese)-like domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0704,10,0.3,0.121,0.1,0.00568,0.00568,0.806,0,0,-1,1.8
ENSMUSG00000069038,GM4906,predicted gene 4906,nucleosome|cellular_component|nucleus|chromosome|,biological_process|,molecular_function|DNA binding|,10,0.1,0.0771,10,0,0,0.1,0.00562,0.00562,0.807,0,0,-1.4,1.5
ENSMUSG00000017767,SPATA25,spermatogenesis associated 25,membrane|integral component of membrane|,spermatogenesis|cell differentiation|,None,10,-1.1,1.57,10,0.1,0.177,0,0,0,0.809,0,0,-2,0.8
ENSMUSG00000038459,ABHD17C,abhydrolase domain containing 17C,cellular_component|,biological_process|,GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1,2
ENSMUSG00000047832,CDCA4,cell division cycle associated 4,nucleus|,biological_process|,molecular_function|,10,0,0,10,-0.9,0.993,0,0,0,0.809,0,0,-2,1.2
ENSMUSG00000017000,SVS6,seminal vesicle secretory protein 6,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.8,1.4
ENSMUSG00000021280,EXOC3L4,exocyst complex component 3-like 4,exocyst|cellular_component|,exocytosis|biological_process|,molecular_function|,10,0,0,10,-0.1,0.129,0,0,0,0.809,0,0,-1.2,1.9
ENSMUSG00000098132,RASSF10,Ras association (RalGDS/AF-6) domain family (N-terminal) member 10,cellular_component|cytoplasm|cytoskeleton|,signal transduction|biological_process|,molecular_function|,9,0.4,1.28,9,0,0,0,0,0,0.809,0,0,-0.9,2
ENSMUSG00000007721,CCDC124,coiled-coil domain containing 124,cytoplasm|cytoskeleton|plasma membrane|,cell cycle|biological_process|cell division|,poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000037936,SCARB1,"scavenger receptor class B, member 1",cytoplasm|lysosomal membrane|plasma membrane|plasma membrane|integral component of plasma membrane|caveola|cell surface|membrane|integral component of membrane|microvillus membrane|extracellular vesicular exosome|,"endothelial cell proliferation|pattern recognition receptor signaling pathway|androgen biosynthetic process|cholesterol catabolic process|cholesterol catabolic process|lipid transport|receptor-mediated endocytosis|receptor-mediated endocytosis|phagocytosis, recognition|cell adhesion|positive regulation of triglyceride biosynthetic process|positive regulation of cholesterol storage|positive regulation of cholesterol storage|regulation of phosphatidylcholine catabolic process|phospholipid transport|lipopolysaccharide transport|cholesterol transport|cholesterol transport|lipopolysaccharide-mediated signaling pathway|detection of lipopolysaccharide|cholesterol efflux|high-density lipoprotein particle remodeling|low-density lipoprotein particle clearance|high-density lipoprotein particle clearance|high-density lipoprotein particle clearance|cholesterol homeostasis|blood vessel endothelial cell migration|recognition of apoptotic cell|recognition of apoptotic cell|reverse cholesterol transport|adhesion of symbiont to host|regulation of phagocytosis|positive regulation of nitric-oxide synthase activity|triglyceride homeostasis|cholesterol import|cholesterol import|",lipopolysaccharide binding|phosphatidylserine binding|lipopolysaccharide receptor activity|high-density lipoprotein particle binding|low-density lipoprotein particle binding|low-density lipoprotein particle binding|apolipoprotein binding|apolipoprotein binding|apolipoprotein A-I binding|protein homodimerization activity|high-density lipoprotein particle receptor activity|high-density lipoprotein particle receptor activity|,10,0,0,10,-0.1,0.105,0,0,0,0.809,0,0,-1.5,1.4
ENSMUSG00000033722,BC034090,cDNA sequence BC034090,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.8,0.965,0,0,0,0.809,0,0,-2,0.8
ENSMUSG00000004043,STAT5A,signal transducer and activator of transcription 5A,nucleus|nucleus|cytoplasm|cytoplasm|,"allantoin metabolic process|luteinization|natural killer cell differentiation|citrate metabolic process|2-oxoglutarate metabolic process|succinate metabolic process|oxaloacetate metabolic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|isoleucine metabolic process|valine metabolic process|creatine metabolic process|fatty acid metabolic process|signal transduction|JAK-STAT cascade|JAK-STAT cascade|female pregnancy|lactation|positive regulation of cell proliferation|positive regulation of cell proliferation|peptidyl-tyrosine phosphorylation|regulation of steroid metabolic process|cytokine-mediated signaling pathway|taurine metabolic process|lipid storage|regulation of cell adhesion|regulation of epithelial cell differentiation|mammary gland development|positive regulation of natural killer cell differentiation|negative regulation of mast cell apoptotic process|T cell differentiation in thymus|prolactin signaling pathway|regulation of multicellular organism growth|positive regulation of multicellular organism growth|positive regulation of activated T cell proliferation|positive regulation of activated T cell proliferation|T cell homeostasis|negative regulation of apoptotic process|response to peptide hormone|positive regulation of interleukin-2 biosynthetic process|positive regulation of B cell differentiation|positive regulation of gamma-delta T cell differentiation|positive regulation of lymphocyte differentiation|negative regulation of erythrocyte differentiation|positive regulation of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|positive regulation of natural killer cell mediated cytotoxicity|creatinine metabolic process|development of secondary female sexual characteristics|development of secondary male sexual characteristics|development of secondary male sexual characteristics|Peyer's patch development|positive regulation of inflammatory response|mammary gland involution|positive regulation of mast cell differentiation|JAK-STAT cascade involved in growth hormone signaling pathway|prostate gland epithelium morphogenesis|epithelial cell differentiation involved in prostate gland development|mammary gland epithelium development|mammary gland epithelium development|positive regulation of mast cell proliferation|cellular response to granulocyte macrophage colony-stimulating factor stimulus|",RNA polymerase II core promoter sequence-specific DNA binding|DNA binding|double-stranded DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity|calcium ion binding|protein binding|protein phosphatase binding|sequence-specific DNA binding|,10,-0.1,0.188,10,0.4,0.326,0,0,0,0.809,0,0,-1.2,1.8
ENSMUSG00000062327,T,t-complex,None,None,None,10,0,0,10,0.1,0.265,0,0,0,0.809,0,0,-2,1
ENSMUSG00000054905,STFA3,stefin A3,None,None,None,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000019854,REPS1,RalBP1 associated Eps domain containing protein,plasma membrane|coated pit|membrane|,receptor-mediated endocytosis|,calcium ion binding|protein binding|SH3 domain binding|metal ion binding|,10,-0.1,0.556,10,0,0,0,0,0,0.809,0,0,-1.1,1.9
ENSMUSG00000025871,4833439L19RIK,RIKEN cDNA 4833439L19 gene,cytoplasm|,biological_process|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0.1,0.312,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000034687,FRAS1,Fraser syndrome 1 homolog (human),basement membrane|plasma membrane|membrane|integral component of membrane|sublamina densa|,morphogenesis of an epithelium|metanephros morphogenesis|cell communication|protein transport|embryonic limb morphogenesis|skin development|palate development|,protein binding|metal ion binding|,10,-0.3,0.455,10,0,0,0,0,0,0.809,0,0,-1.7,1.2
ENSMUSG00000020305,ASB3,ankyrin repeat and SOCS box-containing 3,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000020648,DUS4L,dihydrouridine synthase 4-like (S. cerevisiae),cellular_component|,tRNA processing|oxidation-reduction process|,"catalytic activity|oxidoreductase activity|enoyl-[acyl-carrier-protein] reductase activity|tRNA dihydrouridine synthase activity|2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity|cis-2,3-dihydrodiol DDT dehydrogenase activity|trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity|cis-chlorobenzene dihydrodiol dehydrogenase activity|2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity|trans-1,2-dihydrodiolphenanthrene dehydrogenase activity|3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity|benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity|benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity|citronellyl-CoA dehydrogenase activity|menthone dehydrogenase activity|phthalate 3,4-cis-dihydrodiol dehydrogenase activity|cinnamate reductase activity|flavin adenine dinucleotide binding|NADPH-dependent curcumin reductase activity|NADPH-dependent dihydrocurcumin reductase activity|",10,0,0,10,0.2,0.447,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000049670,MORN4,MORN repeat containing 4,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.51,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000028645,SLC2A1,"solute carrier family 2 (facilitated glucose transporter), member 1",female pronucleus|intracellular|cytoplasm|cytoplasm|plasma membrane|plasma membrane|integral component of plasma membrane|caveola|cell-cell junction|membrane|integral component of membrane|basolateral plasma membrane|midbody|cortical actin cytoskeleton|vesicle|extracellular vesicular exosome|blood microparticle|,protein complex assembly|transport|carbohydrate transport|glucose transport|glucose transport|hexose transmembrane transport|cellular response to glucose starvation|xenobiotic transport|transmembrane transport|dehydroascorbic acid transport|dehydroascorbic acid transport|,transporter activity|glucose transmembrane transporter activity|protein binding|kinase binding|transmembrane transporter activity|substrate-specific transmembrane transporter activity|dehydroascorbic acid transporter activity|dehydroascorbic acid transporter activity|identical protein binding|xenobiotic transporter activity|protein self-association|D-glucose transmembrane transporter activity|D-glucose transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000028071,SH2D2A,SH2 domain containing 2A,cytoplasm|plasma membrane|membrane|,cell proliferation|positive regulation of signal transduction|,SH3/SH2 adaptor activity|protein binding|SH3 domain binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000034645,ZYG11A,"zyg-11 family member A, cell cycle regulator",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0734,0,0,0,0.809,0,0,-1.8,1.1
ENSMUSG00000048038,4932418E24RIK,RIKEN cDNA 4932418E24 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.25,0,0,0,0.809,0,0,-1.9,1.3
ENSMUSG00000058656,SAMD12,sterile alpha motif domain containing 12,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.31,0,0,0,0.809,0,0,-2,0.9
ENSMUSG00000090685,GM9047,predicted gene 9047,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.8,1.3
ENSMUSG00000063605,CCDC102A,coiled-coil domain containing 102A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000061111,FAM195B,"family with sequence similarity 195, member B",cellular_component|,biological_process|,molecular_function|,9,0.6,0.551,9,0.1,0.0866,0,0,0,0.809,0,0,-0.9,2
ENSMUSG00000048458,FAM212B,"family with sequence similarity 212, member B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000006476,NSMF,NMDA receptor synaptonuclear signaling and neuronal migration factor,nucleus|nucleus|nuclear envelope|nuclear euchromatin|cytoplasm|cytoplasm|cytoskeleton|plasma membrane|postsynaptic density|membrane|nuclear matrix|cell junction|dendrite|cortical cytoskeleton|nuclear membrane|cell projection|neuron projection|perikaryon|synapse|postsynaptic membrane|apical dendrite|,positive regulation of protein dephosphorylation|regulation of neuron apoptotic process|regulation of neuronal synaptic plasticity|regulation of dendrite morphogenesis|cellular response to amino acid stimulus|cellular response to electrical stimulus|cellular response to gonadotropin stimulus|positive regulation of neuron migration|,calcium-dependent protein binding|,10,-0.1,0.279,10,0,0,0,0,0,0.809,0,0,-1,2
ENSMUSG00000041445,MMRN2,multimerin 2,extracellular region|proteinaceous extracellular matrix|basement membrane|extracellular space|extracellular vesicular exosome|,angiogenesis|negative regulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of cell migration involved in sprouting angiogenesis|,None,10,0.1,0.401,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000027778,IFT80,intraflagellar transport 80,intracellular|cell|cytoplasm|centrosome|cytoskeleton|cilium|cilium|intraciliary transport particle B|ciliary basal body|cell projection|,osteoblast differentiation|osteoblast differentiation|chondrocyte differentiation|chondrocyte differentiation|smoothened signaling pathway|intraciliary transport|cilium assembly|positive regulation of smoothened signaling pathway|negative regulation of epithelial cell proliferation|cilium morphogenesis|bone morphogenesis|negative regulation of non-canonical Wnt signaling pathway|,molecular_function|,10,0.1,0.448,10,-0.6,1.71,0,0,0,0.809,0,0,-1.9,0.9
ENSMUSG00000046605,B3GNTL1,"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1",cellular_component|,biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0.1,0.126,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000057054,INCA1,"inhibitor of CDK, cyclin A1 interacting protein 1",nucleus|cytoplasm|,negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cell proliferation|negative regulation of cyclin-dependent protein serine/threonine kinase activity|negative regulation of cyclin-dependent protein serine/threonine kinase activity|positive regulation of apoptotic signaling pathway|,cyclin-dependent protein serine/threonine kinase inhibitor activity|cyclin binding|cyclin binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000060224,PYROXD2,pyridine nucleotide-disulphide oxidoreductase domain 2,cellular_component|,biological_process|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000065979,CPPED1,calcineurin-like phosphoesterase domain containing 1,cytoplasm|extracellular vesicular exosome|,biological_process|,molecular_function|phosphoprotein phosphatase activity|hydrolase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.2,1.9
ENSMUSG00000003469,PHYHIP,phytanoyl-CoA hydroxylase interacting protein,cellular_component|,biological_process|,protein binding|,10,-0.3,0.665,10,0,0,0,0,0,0.809,0,0,-2,0.8
ENSMUSG00000021982,CDADC1,cytidine and dCMP deaminase domain containing 1,cellular_component|,biological_process|,catalytic activity|zinc ion binding|hydrolase activity|metal ion binding|,10,0.3,0.241,10,0,0,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000084883,CCDC85C,coiled-coil domain containing 85C,tight junction|cell junction|apical junction complex|,multicellular organismal development|cerebral cortex development|,molecular_function|,10,0.2,0.306,10,0,0,0,0,0,0.809,0,0,-1.2,1.7
ENSMUSG00000023979,GUCA1B,guanylate cyclase activator 1B,photoreceptor outer segment|photoreceptor inner segment|plasma membrane|membrane|,visual perception|phototransduction|regulation of guanylate cyclase activity|positive regulation of guanylate cyclase activity|response to stimulus|,calcium ion binding|calcium sensitive guanylate cyclase activator activity|guanylate cyclase regulator activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000041488,STX3,syntaxin 3,cell|plasma membrane|cell-cell junction|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|secretory granule|dendrite|growth cone|SNARE complex|specific granule|azurophil granule|neuron projection|extracellular vesicular exosome|,transport|neurotransmitter transport|intracellular protein transport|exocytosis|vesicle-mediated transport|neuron projection development|long-term synaptic potentiation|membrane fusion|,SNAP receptor activity|protein binding|arachidonic acid binding|,10,0.2,0.25,10,0,0,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000049288,LIX1L,Lix1-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0317,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000039481,NRTN,neurturin,extracellular region|axon|,neural crest cell migration|transmembrane receptor protein tyrosine kinase signaling pathway|nerve development|neuron projection development|,growth factor activity|growth factor activity|,10,0.1,0.301,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000035967,DDX26B,DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.459,10,0,0,0,0,0,0.809,0,0,-1.7,1.2
ENSMUSG00000033409,SYCE1L,synaptonemal complex central element protein 1 like,synaptonemal complex|cellular_component|,meiotic nuclear division|meiotic prophase I|synaptonemal complex assembly|biological_process|synaptonemal complex organization|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000035431,SSTR1,somatostatin receptor 1,cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|glutamate receptor signaling pathway|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|somatostatin signaling pathway|somatostatin signaling pathway|,signal transducer activity|G-protein coupled receptor activity|somatostatin receptor activity|somatostatin receptor activity|somatostatin receptor activity|protein binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000015702,ANXA9,annexin A9,cytosol|cell surface|extracellular vesicular exosome|,signal transduction|synaptic transmission|single organismal cell-cell adhesion|,phosphatidylserine binding|calcium ion binding|phospholipid binding|calcium-dependent phospholipid binding|acetylcholine receptor activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000025038,EFHC2,EF-hand domain (C-terminal) containing 2,cellular_component|,biological_process|,molecular_function|calcium ion binding|,10,-0.1,0.0336,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000021711,TRAPPC13,trafficking protein particle complex 13,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.3,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000031452,1700029H14RIK,RIKEN cDNA 1700029H14 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.6,0.453,0,0,0,0.809,0,0,-2,0.8
ENSMUSG00000071015,GM136,predicted gene 136,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.0368,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000026857,NTMT1,N-terminal Xaa-Pro-Lys N-methyltransferase 1,nucleus|cytoplasm|,spindle organization|chromosome segregation|N-terminal peptidyl-alanine trimethylation|N-terminal peptidyl-proline dimethylation|N-terminal peptidyl-proline dimethylation|methylation|N-terminal peptidyl-serine dimethylation|N-terminal peptidyl-serine trimethylation|,methyltransferase activity|protein methyltransferase activity|protein methyltransferase activity|transferase activity|,10,0,0,10,0.1,0.267,0,0,0,0.809,0,0,-1.3,1.8
ENSMUSG00000074925,PTAR1,protein prenyltransferase alpha subunit repeat containing 1,cellular_component|,biological_process|,molecular_function|,10,1,0.847,10,0.4,0.4,0,0,0,0.809,0,0,-0.5,2
ENSMUSG00000061082,PLAC1,placental specific protein 1,cellular_component|extracellular region|,multicellular organismal development|spongiotrophoblast layer developmental growth|,molecular_function|,10,0,0,10,-0.3,1.16,0,0,0,0.809,0,0,-1.9,1
ENSMUSG00000025466,FUOM,fucose mutarotase,cellular_component|,monosaccharide metabolic process|fucose metabolic process|fucosylation|negative regulation of neuron differentiation|female mating behavior|,"isomerase activity|racemase and epimerase activity, acting on carbohydrates and derivatives|fucose binding|fucose binding|monosaccharide binding|",10,0.4,0.0279,10,0,0,0,0,0,0.809,0,0,-1.3,1.8
ENSMUSG00000056130,TICAM2,toll-like receptor adaptor molecule 2,cytoplasm|endosome|early endosome|late endosome|endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|membrane|interleukin-1 receptor complex|,regulation of cytokine production|immune system process|inflammatory response|signal transduction|positive regulation of interferon-gamma production|positive regulation of interleukin-6 production|negative regulation of toll-like receptor 4 signaling pathway|positive regulation of toll-like receptor 4 signaling pathway|TRAM-dependent toll-like receptor 4 signaling pathway|regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|innate immune response|response to interleukin-12|cellular response to lipopolysaccharide|negative regulation of chemokine (C-C motif) ligand 5 production|positive regulation of chemokine (C-C motif) ligand 5 production|positive regulation of chemokine (C-C motif) ligand 5 production|positive regulation of interleukin-18-mediated signaling pathway|positive regulation of interleukin-18-mediated signaling pathway|,signal transducer activity|interleukin-1 receptor binding|protein binding|phospholipid binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000027315,SPINT1,"serine protease inhibitor, Kunitz type 1",extracellular region|extracellular space|extracellular vesicular exosome|,embryonic placenta development|negative regulation of peptidase activity|extracellular matrix organization|branching involved in labyrinthine layer morphogenesis|placenta blood vessel development|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000054280,PRR14L,proline rich 14-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.7
ENSMUSG00000046519,GOLPH3L,golgi phosphoprotein 3-like,Golgi apparatus|membrane|,Golgi organization|positive regulation of protein secretion|,lipid binding|phosphatidylinositol-4-phosphate binding|,10,0,0,10,0.1,0.0125,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000020941,MAP3K14,mitogen-activated protein kinase kinase kinase 14,intracellular|cytoplasm|,MAPK cascade|activation of MAPKK activity|protein phosphorylation|protein phosphorylation|immune response|I-kappaB kinase/NF-kappaB signaling|phosphorylation|signal transduction by phosphorylation|NIK/NF-kappaB signaling|positive regulation of I-kappaB kinase/NF-kappaB signaling|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|NF-kappaB-inducing kinase activity|MAP kinase kinase kinase activity|protein binding|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0.4,0.118,10,0,0,0,0,0,0.809,0,0,-1,1.9
ENSMUSG00000044906,4930503L19RIK,RIKEN cDNA 4930503L19 gene,extracellular region|,None,None,10,0,0,10,0.4,0.392,0,0,0,0.809,0,0,-1.6,1.6
ENSMUSG00000051098,MBLAC2,metallo-beta-lactamase domain containing 2,extracellular vesicular exosome|,biological_process|,GPI-anchor transamidase activity|hydrolase activity|metal ion binding|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000078235,FAM43B,"family with sequence similarity 43, member B",cellular_component|,biological_process|,molecular_function|,8,1,1.58,8,-0.1,0.0137,0,0,0,0.809,0,0,-0.9,2
ENSMUSG00000025723,NMB,neuromedin B,extracellular region|neuron projection|,positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|positive regulation of cell proliferation|glucose homeostasis|positive regulation of hormone secretion|negative regulation of hormone secretion|arachidonic acid secretion|,neuromedin B receptor binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000091680,KLHDC7B,kelch domain containing 7B,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.135,10,-0.8,0.542,0,0,0,0.809,0,0,-2,0.7
ENSMUSG00000022803,POPDC2,popeye domain containing 2,membrane|integral component of membrane|,regulation of heart rate|regulation of membrane potential|sinoatrial node cell development|,cAMP binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-2,1
ENSMUSG00000025983,CCDC150,coiled-coil domain containing 150,cellular_component|,biological_process|,molecular_function|,10,0.1,0.263,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000026974,ZMYND19,"zinc finger, MYND domain containing 19",cytoplasm|plasma membrane|membrane|synapse|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,-0.2,0.104,0,0,0,0.809,0,0,-1.8,1.2
ENSMUSG00000050087,CBY3,chibby homolog 3 (Drosophila),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.295,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000056050,MIA3,melanoma inhibitory activity 3,endoplasmic reticulum|endoplasmic reticulum membrane|endoplasmic reticulum membrane|membrane|membrane|integral component of membrane|,chondrocyte development|positive regulation of leukocyte migration|transport|exocytosis|negative regulation of cell adhesion|protein transport|vesicle-mediated transport|collagen fibril organization|negative regulation of cell migration|positive regulation of bone mineralization|wound healing|,molecular_function|,10,0.1,0.0843,10,0,0,0,0,0,0.809,0,0,-1.3,1.6
ENSMUSG00000022902,STFA2,stefin A2,cellular_component|intracellular|cytoplasm|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|,endopeptidase inhibitor activity|cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,4,0,0,4,-0.1,0.124,0,0,0,0.809,0,0,-2,1.5
ENSMUSG00000035852,MISP,mitotic spindle positioning,cellular_component|cytoplasm|cytoskeleton|cell junction|,cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|actin binding|,10,0.4,0.181,10,0,0,0,0,0,0.809,0,0,-0.9,1.9
ENSMUSG00000031174,RPGR,retinitis pigmentosa GTPase regulator,photoreceptor outer segment|intracellular|cell|cytoplasm|Golgi apparatus|centrosome|cytoskeleton|cilium|cilium|ciliary basal body|sperm flagellum|cell projection|primary cilium|,visual perception|visual perception|cell projection organization|intraciliary transport|cilium assembly|eye photoreceptor cell development|response to stimulus|,guanyl-nucleotide exchange factor activity|protein binding|poly(A) RNA binding|,10,-0.4,1.03,10,0,0,0,0,0,0.809,0,0,-1.8,1
ENSMUSG00000070331,QRICH2,glutamine rich 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.502,0,0,0,0.809,0,0,-1.5,1.7
ENSMUSG00000055609,HBA-X,"hemoglobin X, alpha-like embryonic chain in Hba complex",hemoglobin complex|,negative regulation of transcription from RNA polymerase II promoter|transport|oxygen transport|erythrocyte maturation|,oxygen transporter activity|iron ion binding|oxygen binding|heme binding|metal ion binding|,10,0.1,0.475,10,-0.2,0.467,0,0,0,0.809,0,0,-1.6,1.3
ENSMUSG00000040136,ABCC8,"ATP-binding cassette, sub-family C (CFTR/MRP), member 8",plasma membrane|voltage-gated potassium channel complex|synaptic vesicle membrane|sarcolemma|,response to pH|response to zinc ion|positive regulation of potassium ion transport|negative regulation of insulin secretion|cellular response to organic substance|potassium ion transmembrane transport|,nucleotide binding|potassium channel activity|ATP binding|syntaxin binding|ion channel binding|,10,0,0,10,-0.1,0.0236,0,0,0,0.809,0,0,-1.8,1.1
ENSMUSG00000023064,SNCG,"synuclein, gamma",cytoplasm|cytoskeleton|plasma membrane|axon|neuronal cell body|neuronal cell body|axon terminus|perinuclear region of cytoplasm|extracellular vesicular exosome|,synaptic transmission|adult locomotory behavior|protein secretion|regulation of dopamine secretion|regulation of neurotransmitter secretion|synapse organization|,protein binding|alpha-tubulin binding|beta-tubulin binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-2,1.1
ENSMUSG00000039639,KCNE1,"potassium voltage-gated channel, Isk-related subfamily, member 1",endoplasmic reticulum|Golgi apparatus|voltage-gated potassium channel complex|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|Z disc|,epithelial cell maturation|transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|heart contraction|cellular response to acidity|potassium ion transmembrane transport|regulation of heart rate by cardiac conduction|negative regulation of protein targeting to membrane|positive regulation of potassium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|protein heterodimerization activity|,10,0.1,0.0421,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000027397,SLC20A1,"solute carrier family 20, member 1",plasma membrane|membrane|integral component of membrane|,transport|sodium ion transport|phosphate ion transport|signal transduction|phosphate ion transmembrane transport|sodium ion transmembrane transport|positive regulation of I-kappaB kinase/NF-kappaB signaling|,signal transducer activity|inorganic phosphate transmembrane transporter activity|high affinity inorganic phosphate:sodium symporter activity|symporter activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000032468,ARMC8,armadillo repeat containing 8,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0186,10,0.4,1.34,0,0,0,0.809,0,0,-1.4,1.5
ENSMUSG00000079283,2310009B15RIK,RIKEN cDNA 2310009B15 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,0.0354,10,-0.3,0.658,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000050105,GRRP1,glycine/arginine rich protein 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0211,10,0,0,0,0,0,0.809,0,0,-1.7,1.2
ENSMUSG00000026927,SDCCAG3,serologically defined colon cancer antigen 3,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-2,1.1
ENSMUSG00000051817,SOX12,SRY (sex determining region Y)-box 12,nucleus|protein-DNA complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|spinal cord development|positive regulation of transcription from RNA polymerase II promoter|protein-DNA complex assembly|",transcription regulatory region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription coactivator activity|DNA binding|,10,-0.1,0.195,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000002031,IFT46,intraflagellar transport 46,intracellular|cell|cytoplasm|centrosome|cytoskeleton|cilium|cilium|intraciliary transport particle B|motile primary cilium|motile cilium|cell projection|ciliary membrane|primary cilium|ciliary base|,smoothened signaling pathway|protein transport|regulation of protein stability|axoneme assembly|intraciliary transport|intraciliary transport|cilium assembly|cilium organization|cilium-dependent cell motility|regulation of cilium assembly|,protein binding|,10,0.3,0.382,10,-0.2,0.339,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000030701,PLEKHB1,"pleckstrin homology domain containing, family B (evectins) member 1",Golgi membrane|photoreceptor outer segment|cytoplasm|membrane|integral component of membrane|integral component of membrane|,multicellular organismal development|,protein binding|protein C-terminus binding|protein homodimerization activity|,10,0.4,1.07,10,0,0,0,0,0,0.809,0,0,-0.9,2
ENSMUSG00000020846,FAM101B,"family with sequence similarity 101, member B",actin cytoskeleton|,epithelial to mesenchymal transition|actin cytoskeleton organization|actin cytoskeleton organization|,filamin binding|,10,0,0,10,-1.1,1.34,0,0,0,0.809,0,0,-2,1.1
ENSMUSG00000067653,ANKRD23,ankyrin repeat domain 23,nucleus|nucleus|intercalated disc|myofibril|I band|,fatty acid metabolic process|,titin binding|,9,0.1,0.31,9,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000029477,MORN3,MORN repeat containing 3,nucleus|,biological_process|,molecular_function|,10,-0.1,0.053,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000036644,TBC1D9B,"TBC1 domain family, member 9B",cellular_component|membrane|integral component of membrane|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|calcium ion binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000011034,SLC5A1,"solute carrier family 5 (sodium/glucose cotransporter), member 1",brush border|cell-cell junction|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|brush border membrane|extracellular vesicular exosome|,metanephros development|transport|ion transport|sodium ion transport|carbohydrate transport|glucose transport|glucose transport|hexose transmembrane transport|sodium ion transmembrane transport|intestinal absorption|transmembrane transport|,transporter activity|glucose transmembrane transporter activity|glucose:sodium symporter activity|symporter activity|,10,0,0,10,-0.9,0.97,0,0,0,0.809,0,0,-2,0.7
ENSMUSG00000029392,RILPL1,Rab interacting lysosomal protein-like 1,intracellular|cell|nucleus|cytoplasm|centrosome|cytosol|cytoskeleton|plasma membrane|cilium|cell projection|primary cilium|,epithelial cell morphogenesis|transport|intracellular protein transport|protein transport|regulation of neuron death|regulation of neuron death|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.2,1.8
ENSMUSG00000004366,SST,somatostatin,extracellular region|extracellular space|neuronal cell body|,regulation of cell migration|,hormone activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000024241,SOS1,son of sevenless homolog 1 (Drosophila),intracellular|plasma membrane|postsynaptic density|neuronal cell body|,small GTPase mediated signal transduction|Ras protein signal transduction|fibroblast growth factor receptor signaling pathway|positive regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|regulation of Rho protein signal transduction|neurotrophin TRK receptor signaling pathway|regulation of small GTPase mediated signal transduction|positive regulation of small GTPase mediated signal transduction|,DNA binding|guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|protein binding|SH3 domain binding|protein heterodimerization activity|,7,0,0,7,0.6,0.279,0,0,0,0.809,0,0,-1.2,2
ENSMUSG00000020528,PRPSAP2,phosphoribosyl pyrophosphate synthetase-associated protein 2,ribose phosphate diphosphokinase complex|protein complex|,nucleotide biosynthetic process|bone development|,magnesium ion binding|molecular_function|ribose phosphate diphosphokinase activity|,9,0,0,9,0.2,0.281,0,0,0,0.809,0,0,-1.3,1.8
ENSMUSG00000020381,3010026O09RIK,RIKEN cDNA 3010026O09 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.23,0,0,0,0.809,0,0,-1.4,1.5
ENSMUSG00000067750,KHDC1A,KH domain containing 1A,cytoplasm|,apoptotic process|biological_process|,RNA binding|protein binding|poly(U) RNA binding|identical protein binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000031853,BC021891,cDNA sequence BC021891,cellular_component|,protein phosphorylation|phosphorylation|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|MAP kinase kinase kinase activity|protein tyrosine kinase activity|ATP binding|kinase activity|transferase activity|transferase activity, transferring phosphorus-containing groups|",10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000038980,RBBP8NL,RBBP8 N-terminal like,extracellular space|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000061878,SPHK1,sphingosine kinase 1,nucleus|cytoplasm|cytosol|plasma membrane|synaptic vesicle|membrane|axon|neuron projection|,blood vessel development|positive regulation of protein phosphorylation|positive regulation of neurotransmitter secretion|sphingosine metabolic process|inflammatory response|protein kinase C-activating G-protein coupled receptor signaling pathway|brain development|metabolic process|positive regulation of cell proliferation|regulation of tumor necrosis factor-mediated signaling pathway|positive regulation of neuron projection development|phosphorylation|cyclooxygenase pathway|calcium-mediated signaling|positive regulation of cell growth|positive regulation of cell migration|positive regulation of protein ubiquitination|regulation of interleukin-1 beta production|positive regulation of NF-kappaB import into nucleus|negative regulation of apoptotic process|positive regulation of angiogenesis|positive regulation of mitotic cell cycle|positive regulation of smooth muscle contraction|lipid phosphorylation|lipid phosphorylation|positive regulation of fibroblast proliferation|positive regulation of NF-kappaB transcription factor activity|,nucleotide binding|magnesium ion binding|DNA binding|NAD+ kinase activity|diacylglycerol kinase activity|calmodulin binding|calmodulin binding|ATP binding|sphinganine kinase activity|sphinganine kinase activity|kinase activity|transferase activity|D-erythro-sphingosine kinase activity|protein phosphatase 2A binding|,10,0.2,0.118,10,-1.3,1.39,0,0,0,0.809,0,0,-2,1
ENSMUSG00000042306,S100A14,S100 calcium binding protein A14,cytoplasm|perinuclear region of cytoplasm|extracellular vesicular exosome|,apoptotic process|toll-like receptor 4 signaling pathway|positive regulation of granulocyte chemotaxis|positive regulation of monocyte chemotaxis|,calcium ion binding|chemokine receptor binding|,10,0.1,0.0375,10,-0.1,0.212,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000031983,2310022B05RIK,RIKEN cDNA 2310022B05 gene,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.2,0.812,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000025154,ARHGAP19,Rho GTPase activating protein 19,intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,0.2,0.735,10,-0.1,0.17,0,0,0,0.809,0,0,-1.4,1.5
ENSMUSG00000020546,STXBP4,syntaxin binding protein 4,intracellular|cell|nucleus|cytoplasm|intermediate filament cytoskeleton|extracellular vesicular exosome|,protein targeting|cellular response to DNA damage stimulus|insulin receptor signaling pathway|positive regulation of keratinocyte proliferation|glucose transport|protein stabilization|positive regulation of cell cycle G1/S phase transition|,calcium ion binding|protein binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000031150,CCDC120,coiled-coil domain containing 120,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000030844,RGS10,regulator of G-protein signalling 10,nucleus|cytoplasm|plasma membrane|neuronal cell body|dendritic spine|axon terminus|,negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|protein binding|,10,1,1.14,10,0,0,0,0,0,0.809,0,0,-0.8,2
ENSMUSG00000038619,ENSA,endosulfine alpha,cytoplasm|,cell cycle|mitotic nuclear division|regulation of insulin secretion|cell division|,protein phosphatase inhibitor activity|receptor binding|potassium channel inhibitor activity|,10,0.1,0.156,10,-0.7,0.511,0,0,0,0.809,0,0,-2,1
ENSMUSG00000037833,SH2D4B,SH2 domain containing 4B,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.163,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000015126,TSR3,TSR3 20S rRNA accumulation,cellular_component|,rRNA processing|biological_process|ribosome biogenesis|,molecular_function|,10,0,0,10,0.5,0.766,0,0,0,0.809,0,0,-0.8,2
ENSMUSG00000061759,1700052N19RIK,RIKEN cDNA 1700052N19 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000035007,RUNDC1,RUN domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.328,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000063935,ZAR1,zygote arrest 1,cytoplasm|,multicellular organismal development|biological_process|,molecular_function|,10,0,0,10,0.2,0.11,0,0,0,0.809,0,0,-1.1,1.9
ENSMUSG00000015093,CLIC3,chloride intracellular channel 3,nucleus|cytoplasm|membrane|integral component of membrane|chloride channel complex|extracellular vesicular exosome|,transport|ion transport|chloride transport|regulation of ion transmembrane transport|chloride transmembrane transport|,voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000053783,1700016K19RIK,RIKEN cDNA 1700016K19 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.503,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000028971,CORT,cortistatin,extracellular region|,"adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|regulation of circadian sleep/wake cycle, sleep|",G-protein coupled receptor binding|hormone activity|neuropeptide hormone activity|,9,0,0,9,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000035234,FAM175A,"family with sequence similarity 175, member A",nucleus|BRCA1-A complex|,DNA repair|double-strand break repair|cellular response to DNA damage stimulus|response to ionizing radiation|chromatin modification|G2 DNA damage checkpoint|positive regulation of DNA repair|,polyubiquitin binding|,10,0.2,0.665,10,-1.2,1.79,0,0,0,0.809,0,0,-2,0.9
ENSMUSG00000044629,CNRIP1,cannabinoid receptor interacting protein 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0292,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000029320,1700016H13RIK,RIKEN cDNA 1700016H13 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0259,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000020605,HS1BP3,HCLS1 binding protein 3,cellular_component|,cell surface receptor signaling pathway|T cell differentiation|,protein binding|phosphatidylinositol binding|,10,-0.8,2.42,10,0,0,0,0,0,0.809,0,0,-2,0.5
ENSMUSG00000027654,FAM83D,"family with sequence similarity 83, member D",cellular_component|cytoplasm|cytoskeleton|,cell cycle|mitotic nuclear division|biological_process|cell division|,molecular_function|,10,-0.1,0.0305,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000049680,URGCP,upregulator of cell proliferation,nucleus|cytoplasm|,cell cycle|biological_process|,molecular_function|GTP binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000026832,CYTIP,cytohesin 1 interacting protein,nucleus|cytoplasm|endosome|cell cortex|,regulation of cell adhesion|,None,10,0.1,0.201,10,-0.1,0.129,0,0,0,0.809,0,0,-1.1,1.8
ENSMUSG00000027854,SIKE1,suppressor of IKBKE 1,cytoplasm|,biological_process|,molecular_function|,10,0.1,0.142,10,0,0,0,0,0,0.809,0,0,-1.3,1.8
ENSMUSG00000007207,STX1A,syntaxin 1A (brain),cell|plasma membrane|plasma membrane|plasma membrane|synaptic vesicle|membrane|integral component of membrane|cell junction|secretory granule|synaptic vesicle membrane|SNARE complex|cytoplasmic vesicle|actomyosin|neuron projection|neuron projection|intracellular organelle|protein complex|synapse|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex|synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex|synaptobrevin 2-SNAP-25-syntaxin-1a complex|synaptobrevin 2-SNAP-25-syntaxin-1a complex|,positive regulation of neurotransmitter secretion|transport|neurotransmitter transport|intracellular protein transport|exocytosis|response to gravity|vesicle-mediated transport|calcium ion-dependent exocytosis|regulation of exocytosis|positive regulation of exocytosis|,"SNARE binding|SNARE binding|glycoprotein binding|SNAP receptor activity|protein binding|myosin binding|calcium channel inhibitor activity|protein domain specific binding|protein binding, bridging|myosin head/neck binding|ATP-dependent protein binding|protein heterodimerization activity|protein N-terminus binding|calcium-dependent protein binding|",10,0.1,0.213,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000041341,ATG2B,autophagy related 2B,pre-autophagosomal structure|lipid particle|membrane|extrinsic component of membrane|,autophagic vacuole assembly|mitochondrion degradation|autophagy|cellular response to nitrogen starvation|nucleophagy|,molecular_function|,10,0.1,0.357,10,-0.1,0.0897,0,0,0,0.809,0,0,-1.5,1.4
ENSMUSG00000028995,FAM126A,"family with sequence similarity 126, member A",cytoplasm|plasma membrane|membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.291,0,0,0,0.809,0,0,-1,2
ENSMUSG00000050359,SPRR1A,small proline-rich protein 1A,cornified envelope|cytoplasm|cell periphery|,peptide cross-linking|keratinocyte differentiation|keratinization|,"structural molecule activity|protein binding, bridging|",10,-0.2,0.178,10,0,0,0,0,0,0.809,0,0,-1.2,1.9
ENSMUSG00000019813,CEP57L1,centrosomal protein 57-like 1,cellular_component|cytoplasm|cytoskeleton|microtubule|,biological_process|microtubule anchoring|,molecular_function|microtubule binding|identical protein binding|gamma-tubulin binding|,10,0,0,10,0.3,0.505,0,0,0,0.809,0,0,-1.2,1.8
ENSMUSG00000020629,ADI1,acireductone dioxygenase 1,nucleus|cytoplasm|Golgi apparatus|plasma membrane|membrane|,cellular amino acid biosynthetic process|methionine biosynthetic process|L-methionine salvage from methylthioadenosine|oxidation-reduction process|,acireductone dioxygenase [iron(II)-requiring] activity|oxidoreductase activity|metal ion binding|dioxygenase activity|,10,-0.1,0.118,10,0,0,0,0,0,0.809,0,0,-1.7,1.2
ENSMUSG00000078350,SMIM1,small integral membrane protein 1,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0.3,0.235,0,0,0,0.809,0,0,-1,1.9
ENSMUSG00000046096,BC030336,cDNA sequence BC030336,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0661,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000028461,CCDC107,coiled-coil domain containing 107,None,None,None,10,-0.1,0.0812,10,0,0,0,0,0,0.809,0,0,-1.2,1.7
ENSMUSG00000034833,TESPA1,"thymocyte expressed, positive selection associated 1",cytoplasm|endoplasmic reticulum|COP9 signalosome|membrane|,COP9 signalosome assembly|positive regulation of T cell differentiation in thymus|positive regulation of T cell receptor signaling pathway|,molecular_function|receptor binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.9,1.1
ENSMUSG00000037151,LRRC20,leucine rich repeat containing 20,cellular_component|,biological_process|,molecular_function|,10,0.6,1.14,9,-0.3,1.23,0,0,0,0.809,0,0,-1,2
ENSMUSG00000090141,GM614,predicted gene 614,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000040943,TET2,tet methylcytosine dioxygenase 2,nucleus|,kidney development|5-methylcytosine catabolic process|protein O-linked glycosylation|protein O-linked glycosylation|cell cycle|post-embryonic development|chromatin modification|hemopoiesis|myeloid cell differentiation|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|oxidation-reduction process|DNA demethylation|DNA demethylation|DNA demethylation|histone H3-K4 trimethylation|histone H3-K4 trimethylation|,DNA binding|ferrous iron binding|zinc ion binding|oxidoreductase activity|metal ion binding|dioxygenase activity|methylcytosine dioxygenase activity|methylcytosine dioxygenase activity|methylcytosine dioxygenase activity|,10,0,0,10,0.1,0.112,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000074909,RANBP6,RAN binding protein 6,cellular_component|nucleus|cytoplasm|,transport|biological_process|protein transport|,molecular_function|,10,0.1,0.0506,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000021061,SPTB,"spectrin beta, erythrocytic",cytoplasm|cytoskeleton|plasma membrane|spectrin|cell surface|spectrin-associated cytoskeleton|spectrin-associated cytoskeleton|membrane|cortical cytoskeleton|protein complex|,porphyrin-containing compound biosynthetic process|plasma membrane organization|hemopoiesis|actin filament capping|,actin binding|structural constituent of cytoskeleton|ankyrin binding|protein heterodimerization activity|actin filament binding|actin filament binding|,10,0.1,0.1,10,0,0,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000039741,BAHCC1,BAH domain and coiled-coil containing 1,cellular_component|,biological_process|,molecular_function|chromatin binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000061991,HIST1H2AF,"histone cluster 1, H2af",nucleosome|nucleus|chromosome|,biological_process|,DNA binding|protein heterodimerization activity|,3,0,0,3,0.2,0.25,0,0,0,0.809,0,0,-1.6,2
ENSMUSG00000054723,VMAC,vimentin-type intermediate filament associated coiled-coil protein,cytoplasm|type III intermediate filament|,biological_process|,intermediate filament binding|,10,0,0,10,0.1,0.131,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000039981,ZC3H12D,zinc finger CCCH type containing 12D,nucleus|cytoplasm|,negative regulation of cell growth|negative regulation of G1/S transition of mitotic cell cycle|,molecular_function|nuclease activity|endonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0.1,0.071,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000075267,DFNB59,"deafness, autosomal recessive 59 (human)",neuronal cell body|,sensory perception of sound|,molecular_function|,10,-0.1,0.193,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000023151,LRRC69,leucine rich repeat containing 69,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0575,10,-0.1,0.00413,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000032221,MNS1,meiosis-specific nuclear structural protein 1,nucleus|nuclear envelope|intermediate filament|axoneme|sperm flagellum|,meiotic nuclear division|cilium organization|left/right axis specification|,identical protein binding|,10,0.2,0.386,10,0,0,0,0,0,0.809,0,0,-1.1,1.9
ENSMUSG00000079610,ANKRD39,ankyrin repeat domain 39,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.8,1.4
ENSMUSG00000094504,GM5294,predicted gene 5294,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",DNA binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000048899,RIMKLA,ribosomal modification protein rimK-like family member A,cytoplasm|,cellular protein modification process|,nucleotide binding|catalytic activity|ATP binding|ligase activity|metal ion binding|N-acetyl-L-aspartate-L-glutamate ligase activity|,10,-0.1,0.0234,10,0,0,0,0,0,0.809,0,0,-1.9,1.2
ENSMUSG00000025173,WDR45B,WD repeat domain 45B,None,None,None,10,0.1,0.299,10,0,0,0,0,0,0.809,0,0,-1.9,1.1
ENSMUSG00000074358,CCDC61,coiled-coil domain containing 61,centrosome|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.8,1.3
ENSMUSG00000022833,CCDC14,coiled-coil domain containing 14,centrosome|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000079339,GM14446,predicted gene 14446,cellular_component|,biological_process|,molecular_function|,10,0.1,0.222,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000063439,B9D2,B9 protein domain 2,nucleus|cytoplasm|centrosome|cytoskeleton|cilium|membrane|TCTN-B9D complex|ciliary basal body|cell projection|,cell projection organization|cilium assembly|,protein binding|gamma-tubulin binding|,10,0,0,10,0.1,0.0957,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000028339,COL15A1,"collagen, type XV, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|basement membrane|extracellular space|extracellular matrix|extracellular vesicular exosome|,cell adhesion|,structural molecule activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000022587,LY6E,"lymphocyte antigen 6 complex, locus E",cell|plasma membrane|membrane|anchored component of membrane|,in utero embryonic development|adrenal gland development|organ growth|norepinephrine metabolic process|epinephrine secretion|ventricular cardiac muscle tissue morphogenesis|,None,10,-0.1,0.0932,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000042116,VWA1,von Willebrand factor A domain containing 1,extracellular region|proteinaceous extracellular matrix|basement membrane|interstitial matrix|extracellular space|extracellular matrix|extracellular vesicular exosome|,extracellular matrix organization|extracellular matrix organization|behavioral response to pain|,protein binding|identical protein binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.5
ENSMUSG00000073733,RSG1,REM2 and RAB-like small GTPase 1,cellular_component|intracellular|cytoplasm|cytoskeleton|cilium|cell projection|,transport|exocytosis|small GTPase mediated signal transduction|protein transport|cell projection organization|,nucleotide binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000040966,SLC22A2,"solute carrier family 22 (organic cation transporter), member 2",integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|extracellular vesicular exosome|,transport|ion transport|cation transport|organic cation transport|organic cation transport|quaternary ammonium group transport|choline transport|ion transmembrane transport|histamine transport|transmembrane transport|,transporter activity|steroid binding|ion transmembrane transporter activity|organic cation transmembrane transporter activity|organic cation transmembrane transporter activity|choline transmembrane transporter activity|quaternary ammonium group transmembrane transporter activity|transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.1,2
ENSMUSG00000022362,9130401M01RIK,RIKEN cDNA 9130401M01 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.0695,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000029190,D5ERTD579E,"DNA segment, Chr 5, ERATO Doi 579, expressed",cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000031166,WDR13,WD repeat domain 13,nucleus|cytoplasm|,biological_process|,molecular_function|,10,0.1,0.127,10,-0.4,1.36,0,0,0,0.809,0,0,-1.9,1
ENSMUSG00000053560,IER2,immediate early response 2,cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000002580,MIEN1,migration and invasion enhancer 1,cytoplasm|cytosol|cytosol|plasma membrane|membrane|intrinsic component of the cytoplasmic side of the plasma membrane|extracellular vesicular exosome|,apoptotic process|positive regulation of cell migration|negative regulation of apoptotic process|cell redox homeostasis|positive regulation of filopodium assembly|,protein binding|selenium binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000024352,SPATA24,spermatogenesis associated 24,nucleus|nucleus|cytoplasm|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|spermatogenesis|biological_process|cell differentiation|",DNA binding|protein binding|protein homodimerization activity|,10,0.1,0.174,10,-0.3,0.351,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000055809,DNAAF3,"dynein, axonemal assembly factor 3",cellular_component|cytoplasm|,cell projection organization|motile cilium assembly|axonemal dynein complex assembly|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000047904,SSTR2,somatostatin receptor 2,cytoplasm|plasma membrane|plasma membrane|membrane|integral component of membrane|,regulation of muscle contraction|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|peristalsis|somatostatin signaling pathway|somatostatin signaling pathway|,signal transducer activity|G-protein coupled receptor activity|somatostatin receptor activity|somatostatin receptor activity|somatostatin receptor activity|PDZ domain binding|,10,0,0,10,-0.1,0.378,0,0,0,0.809,0,0,-1.6,1.3
ENSMUSG00000018126,BAIAP2L2,BAI1-associated protein 2-like 2,plasma membrane|vesicle membrane|membrane|cell junction|cytoplasmic vesicle|cell-cell contact zone|clathrin complex|,signal transduction|regulation of actin cytoskeleton organization|filopodium assembly|membrane organization|,phospholipid binding|cytoskeletal adaptor activity|lipid binding|SH3 domain binding|,10,-0.2,0.000282,10,0.1,0.0151,0,0,0,0.809,0,0,-1.6,1.3
ENSMUSG00000026955,SAPCD2,suppressor APC domain containing 2,nucleus|nucleolus|cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0.1,0.139,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000051225,FAM83A,"family with sequence similarity 83, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.386,0,0,0,0.809,0,0,-1.9,1
ENSMUSG00000029419,GM996,predicted gene 996,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000055717,SLAIN1,"SLAIN motif family, member 1",cellular_component|,biological_process|,molecular_function|,10,0.2,1.35,10,0,0,0,0,0,0.809,0,0,-1.3,1.6
ENSMUSG00000048000,GIGYF2,GRB10 interacting GYF protein 2,membrane|,feeding behavior|adult locomotory behavior|post-embryonic development|negative regulation of translation|spinal cord motor neuron differentiation|mitotic G1 DNA damage checkpoint|multicellular organism growth|cellular protein metabolic process|insulin-like growth factor receptor signaling pathway|homeostasis of number of cells within a tissue|musculoskeletal movement|neuromuscular process controlling balance|,protein binding|poly(A) RNA binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000051065,MB21D2,Mab-21 domain containing 2,cellular_component|,biological_process|,protein complex binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000025405,INHBC,inhibin beta-C,extracellular region|extracellular vesicular exosome|,None,hormone activity|growth factor activity|,10,-0.1,0.263,10,0.3,0.0618,0,0,0,0.809,0,0,-1,1.8
ENSMUSG00000040557,WBSCR27,Williams Beuren syndrome chromosome region 27 (human),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000090113,NHLRC4,NHL repeat containing 4,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000029097,TRMT44,tRNA methyltransferase 44,cellular_component|cytoplasm|,tRNA processing|biological_process|methylation|,molecular_function|methyltransferase activity|transferase activity|metal ion binding|,10,0,0,10,-0.1,0.173,0,0,0,0.809,0,0,-1.8,1.2
ENSMUSG00000074227,SPINT2,"serine protease inhibitor, Kunitz type 2",cytoplasm|membrane|integral component of membrane|,negative regulation of peptidase activity|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.1,0.013,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000026972,ARRDC1,arrestin domain containing 1,plasma membrane|cytoplasmic vesicle|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.286,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000027794,SOHLH2,spermatogenesis and oogenesis specific basic helix-loop-helix 2,nucleus|,"primary ovarian follicle growth|transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|multicellular organismal development|spermatogenesis|oocyte differentiation|regulation of gene expression|cell differentiation|positive regulation of transcription from RNA polymerase II promoter|oogenesis|",RNA polymerase II regulatory region sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|protein dimerization activity|,10,0.2,0.318,10,-0.1,0.0272,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000090553,SNRPE,small nuclear ribonucleoprotein E,nucleus|spliceosomal complex|cytoplasm|ribonucleoprotein complex|,"mRNA splicing, via spliceosome|mRNA processing|RNA splicing|",RNA binding|,9,0,0,9,0,0,0,0,0,0.809,0,0,-1.7,1.5
ENSMUSG00000078554,FAM229A,"family with sequence similarity 229, member A",cellular_component|,biological_process|,molecular_function|,10,0.3,0.878,10,0,0,0,0,0,0.809,0,0,-1.1,1.8
ENSMUSG00000029601,IQCD,IQ motif containing D,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0544,0,0,0,0.809,0,0,-1.2,1.7
ENSMUSG00000039715,WDR34,WD repeat domain 34,cytoplasm|centriole|cytoskeleton|axoneme|ciliary basal body|cell projection|,biological_process|,molecular_function|,10,0,0,10,0.1,0.191,0,0,0,0.809,0,0,-1.4,1.5
ENSMUSG00000048537,PHLDB1,"pleckstrin homology-like domain, family B, member 1",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.6,1.5
ENSMUSG00000078137,ANKRD63,ankyrin repeat domain 63,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.887,0,0,0,0.809,0,0,-1.9,1.2
ENSMUSG00000030249,ABCC9,"ATP-binding cassette, sub-family C (CFTR/MRP), member 9",mitochondrion|plasma membrane|plasma membrane|voltage-gated potassium channel complex|ATP-sensitive potassium channel complex|membrane|integral component of membrane|sarcomere|T-tubule|sarcolemma|,transport|potassium ion transport|signal transduction|potassium ion import|defense response to virus|transmembrane transport|,"nucleotide binding|potassium channel activity|potassium channel activity|ATP binding|drug binding|sulfonylurea receptor activity|potassium channel regulator activity|ATPase activity|syntaxin binding|ATPase activity, coupled to transmembrane movement of substances|identical protein binding|ion channel binding|",10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000041025,IFFO2,intermediate filament family orphan 2,cellular_component|intermediate filament|,biological_process|,molecular_function|structural molecule activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-2,1
ENSMUSG00000045176,2310047M10RIK,RIKEN cDNA 2310047M10 gene,cellular_component|,biological_process|,protein binding|,4,0,0,4,0,0,0,0,0,0.809,0,0,-1.7,1.8
ENSMUSG00000038677,SCUBE3,"signal peptide, CUB domain, EGF-like 3",extracellular region|cell surface|,protein homooligomerization|protein heterooligomerization|,calcium ion binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.5
ENSMUSG00000012282,WNT8A,"wingless-type MMTV integration site family, member 8A",extracellular region|proteinaceous extracellular matrix|extracellular space|,cell morphogenesis|regionalization|multicellular organismal development|endoderm development|polarity specification of anterior/posterior axis|polarity specification of proximal/distal axis|Wnt signaling pathway|neuron differentiation|regulation of protein localization|cell fate commitment|establishment of organ orientation|palate development|,receptor binding|frizzled binding|protein binding|,10,0.7,0.54,10,0,0,0,0,0,0.809,0,0,-0.9,2
ENSMUSG00000022364,TBC1D31,"TBC1 domain family, member 31",centrosome|,biological_process|regulation of Rab GTPase activity|,molecular_function|Rab GTPase activator activity|,10,0.2,0.303,10,0,0,0,0,0,0.809,0,0,-1.2,1.8
ENSMUSG00000031809,1700018B08RIK,RIKEN cDNA 1700018B08 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000020717,PECAM1,platelet/endothelial cell adhesion molecule 1,extracellular space|intracellular|plasma membrane|plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|cell junction|smooth muscle contractile fiber|membrane raft|extracellular vesicular exosome|cell periphery|,positive regulation of leukocyte migration|phagocytosis|cellular component movement|cell adhesion|Rho protein signal transduction|regulation of cell migration|negative regulation of actin filament polymerization|negative regulation of Rho GTPase activity|wound healing|positive regulation of tyrosine phosphorylation of Stat5 protein|negative regulation of peptidyl-tyrosine phosphorylation|diapedesis|,protein binding|,10,0,0,10,-0.1,0.00323,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000027175,TCP11L1,t-complex 11 like 1,microtubule|,biological_process|,molecular_function|,10,0,0,10,0.3,0.593,0,0,0,0.809,0,0,-0.9,1.9
ENSMUSG00000020910,ADPRM,"ADP-ribose/CDP-alcohol diphosphatase, manganese dependent",cellular_component|,biological_process|,molecular_function|hydrolase activity|metal ion binding|ADP-ribose diphosphatase activity|CDP-glycerol diphosphatase activity|,10,-0.2,0.582,10,0,0,0,0,0,0.809,0,0,-1.7,1.2
ENSMUSG00000028188,SPATA1,spermatogenesis associated 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000052302,TBC1D30,"TBC1 domain family, member 30",cellular_component|plasma membrane|membrane|,biological_process|regulation of Rab GTPase activity|,molecular_function|Rab GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.8,1.2
ENSMUSG00000093626,GM20654,N/A,None,None,None,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000022906,PARP9,"poly (ADP-ribose) polymerase family, member 9",nucleus|cytoplasm|membrane|,DNA repair|double-strand break repair|cellular response to DNA damage stimulus|regulation of response to interferon-gamma|,NAD+ ADP-ribosyltransferase activity|transferase activity|,10,0.1,0.179,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000030032,WDR54,WD repeat domain 54,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000044566,CAGE1,cancer antigen 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0977,10,0,0,0,0,0,0.809,0,0,-1.6,1.4
ENSMUSG00000057440,MPP7,"membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)",mitochondrion|adherens junction|tight junction|membrane|cell junction|MPP7-DLG1-LIN7 complex|,positive regulation of protein complex assembly|tight junction assembly|protein localization to adherens junction|,protein domain specific binding|protein complex scaffold|protein heterodimerization activity|,10,0.1,0.093,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000038351,SGSM2,small G protein signaling modulator 2,None,regulation of Rab GTPase activity|,Rab GTPase activator activity|,10,-0.2,0.015,10,-1.2,1.63,0,0,0,0.809,0,0,-2,0.4
ENSMUSG00000071562,STFA1,stefin A1,cytoplasm|,negative regulation of endopeptidase activity|,endopeptidase inhibitor activity|,3,0,0,3,0.1,0.066,0,0,0,0.809,0,0,-1.7,1.9
ENSMUSG00000027329,SPEF1,sperm flagellar 1,cytoplasm|cytoskeleton|cilium|motile cilium|cell projection|,biological_process|,molecular_function|,9,0.1,0.255,9,0,0,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000050677,CCDC96,coiled-coil domain containing 96,cellular_component|,biological_process|,molecular_function|,10,0.1,0.089,10,-0.1,0.134,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000060188,CXCL17,chemokine (C-X-C motif) ligand 17,cellular_component|extracellular region|,angiogenesis|chemotaxis|multicellular organismal development|biological_process|cell differentiation|,molecular_function|,10,0.1,0.294,10,-0.1,0.26,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000020173,COBL,cordon-bleu WH2 repeat,ruffle|cytoplasm|cytoskeleton|actin filament|plasma membrane|plasma membrane|cell cortex|cell cortex|membrane|axon|dendrite|cell projection|neuronal cell body|dendritic growth cone|axonal growth cone|perinuclear region of cytoplasm|,neural tube closure|actin filament polymerization|collateral sprouting in absence of injury|actin filament network formation|actin crosslink formation|positive regulation of dendrite development|positive regulation of ruffle assembly|,actin binding|actin monomer binding|protein binding|,10,0,0,10,0.2,0.0294,0,0,0,0.809,0,0,-1.1,1.8
ENSMUSG00000044172,PTX4,pentraxin 4,cellular_component|extracellular region|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.13,10,0.3,0.723,0,0,0,0.809,0,0,-1.1,1.9
ENSMUSG00000028779,PEF1,penta-EF hand domain containing 1,cytoplasm|cytoplasm|membrane|extracellular vesicular exosome|,proteolysis|response to calcium ion|,calcium-dependent cysteine-type endopeptidase activity|calcium ion binding|poly(A) RNA binding|metal ion binding|protein heterodimerization activity|protein dimerization activity|,10,0.1,0.144,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000027194,TTC17,tetratricopeptide repeat domain 17,cytoplasm|cytoskeleton|plasma membrane|actin cytoskeleton|membrane|,cell projection organization|actin filament polymerization|cilium organization|,molecular_function|,10,0.3,0.67,10,0,0,0,0,0,0.809,0,0,-1,1.9
ENSMUSG00000030987,STIM1,stromal interaction molecule 1,cytoplasm|endoplasmic reticulum|cytoskeleton|microtubule|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|growth cone|cortical endoplasmic reticulum|protein complex|,store-operated calcium entry|store-operated calcium entry|detection of calcium ion|transport|ion transport|cation transport|calcium ion transport|activation of store-operated calcium channel activity|regulation of calcium ion transport|calcium ion transmembrane transport|regulation of store-operated calcium entry|,calcium channel regulator activity|calcium ion binding|protein binding|store-operated calcium channel activity|identical protein binding|metal ion binding|microtubule plus-end binding|,10,0.4,0.571,10,0,0,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000044562,RASIP1,Ras interacting protein 1,cytoplasm|Golgi apparatus|perinuclear region of cytoplasm|,angiogenesis|vasculogenesis|signal transduction|positive regulation of cell proliferation|negative regulation of autophagy|regulation of Rho GTPase activity|branching morphogenesis of an epithelial tube|,protein binding|Ras GTPase binding|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.8,1.3
ENSMUSG00000031750,IL34,interleukin 34,extracellular region|extracellular space|extracellular space|,positive regulation of protein phosphorylation|positive regulation of protein phosphorylation|immune system process|inflammatory response|positive regulation of cell proliferation|positive regulation of cell proliferation|innate immune response|,cytokine activity|macrophage colony-stimulating factor receptor binding|macrophage colony-stimulating factor receptor binding|growth factor activity|,10,0.1,0.0264,10,0,0,0,0,0,0.809,0,0,-1.8,1.1
ENSMUSG00000021550,2210016F16RIK,RIKEN cDNA 2210016F16 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000024726,2410127L17RIK,RIKEN cDNA 2410127L17 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0174,10,0,0,0,0,0,0.809,0,0,-1.5,1.4
ENSMUSG00000036568,GLTSCR1L,GLTSCR1-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000068250,AMN1,antagonist of mitotic exit network 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.3,1.8
ENSMUSG00000040663,CLCF1,cardiotrophin-like cytokine factor 1,extracellular region|extracellular space|intracellular|intracellular|extracellular vesicular exosome|CRLF-CLCF1 complex|CNTFR-CLCF1 complex|,positive regulation of immunoglobulin production|positive regulation of type 2 immune response|cell surface receptor signaling pathway|JAK-STAT cascade|positive regulation of cell proliferation|B cell differentiation|positive regulation of B cell proliferation|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of neuron apoptotic process|negative regulation of neuron apoptotic process|positive regulation of isotype switching to IgE isotypes|positive regulation of astrocyte differentiation|regulation of inflammatory response|positive regulation of corticotropin-releasing hormone secretion|regulation of protein kinase B signaling|regulation of ERK1 and ERK2 cascade|negative regulation of motor neuron apoptotic process|,receptor binding|cytokine activity|cytokine activity|ciliary neurotrophic factor receptor binding|ciliary neurotrophic factor receptor binding|ciliary neurotrophic factor receptor binding|protein heterodimerization activity|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-2,1.1
ENSMUSG00000090206,TEPP,"testis, prostate and placenta expressed",cellular_component|,biological_process|,molecular_function|,10,0.6,0.397,10,0,0,0,0,0,0.809,0,0,-0.9,2
ENSMUSG00000038172,TTC39B,tetratricopeptide repeat domain 39B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000047841,BC051628,cDNA sequence BC051628,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.1,0.345,10,-0.1,0.0318,0,0,0,0.809,0,0,-1.9,1
ENSMUSG00000049807,ARHGAP23,Rho GTPase activating protein 23,intracellular|extracellular vesicular exosome|,signal transduction|,molecular_function|GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000039968,RSBN1L,round spermatid basic protein 1-like,cellular_component|,biological_process|,molecular_function|,10,-1.1,1.84,10,0,0,0,0,0,0.809,0,0,-2,0.9
ENSMUSG00000078896,GM8923,predicted gene 8923,cellular_component|,biological_process|,molecular_function|,9,-0.1,0.283,9,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000002396,OCEL1,occludin/ELL domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.1,0.123,10,0,0,0,0,0,0.809,0,0,-1.5,1.5
ENSMUSG00000073608,GM6086,predicted gene 6086,cellular_component|,None,None,10,-0.8,0.705,10,0,0,0,0,0,0.809,0,0,-2,0.9
ENSMUSG00000002797,GGCT,gamma-glutamyl cyclotransferase,cytosol|extracellular vesicular exosome|,release of cytochrome c from mitochondria|glutathione biosynthetic process|,"gamma-glutamylcyclotransferase activity|transferase activity|transferase activity, transferring acyl groups|protein homodimerization activity|",10,-0.1,0.361,10,0.1,0.375,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000028643,CCDC23,coiled-coil domain containing 23,apical part of cell|,protein secretion|negative regulation of endothelial cell migration|negative regulation of protein ubiquitination|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.2,1.9
ENSMUSG00000033256,SHF,Src homology 2 domain containing F,cellular_component|,apoptotic process|biological_process|,molecular_function|,10,0.1,0.104,10,0,0,0,0,0,0.809,0,0,-1.4,1.7
ENSMUSG00000033186,MZT1,mitotic spindle organizing protein 1,cytoplasm|centrosome|spindle|cytoskeleton|gamma-tubulin ring complex|,gamma-tubulin complex localization|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.1,1.9
ENSMUSG00000029089,PACRGL,PARK2 co-regulated-like,cellular_component|,biological_process|,molecular_function|,9,0.1,0.18,9,1.4,1.69,0,0,0,0.809,0,0,-0.9,2
ENSMUSG00000023828,SLC22A3,"solute carrier family 22 (organic cation transporter), member 3",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|organic cation transport|organic cation transport|quaternary ammonium group transport|quaternary ammonium group transport|monoamine transport|dopamine transport|regulation of appetite|ion transmembrane transport|histamine transport|histamine uptake|transmembrane transport|toxin transport|,transporter activity|dopamine transmembrane transporter activity|ion transmembrane transporter activity|organic cation transmembrane transporter activity|organic cation transmembrane transporter activity|quaternary ammonium group transmembrane transporter activity|quaternary ammonium group transmembrane transporter activity|toxin transporter activity|transmembrane transporter activity|,10,-0.3,0.814,10,0.1,0.0532,0,0,0,0.809,0,0,-2,0.8
ENSMUSG00000048445,CCDC57,coiled-coil domain containing 57,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0601,10,0.1,0.127,0,0,0,0.809,0,0,-1.4,1.6
ENSMUSG00000061838,SUCLG2,"succinate-Coenzyme A ligase, GDP-forming, beta subunit",mitochondrion|mitochondrion|plasma membrane|protein complex|succinate-CoA ligase complex (GDP-forming)|,tricarboxylic acid cycle|succinyl-CoA metabolic process|succinate metabolic process|metabolic process|oxidation-reduction process|,nucleotide binding|catalytic activity|succinate-CoA ligase (GDP-forming) activity|succinate-semialdehyde dehydrogenase (NAD+) activity|ATP binding|GTP binding|ligase activity|GDP binding|metal ion binding|protein heterodimerization activity|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.7,1.4
ENSMUSG00000049097,ANKRD34A,ankyrin repeat domain 34A,cytoplasm|,biological_process|,molecular_function|,10,-0.1,0.122,10,0.5,0.153,0,0,0,0.809,0,0,-1.3,1.7
ENSMUSG00000041966,DCAF17,DDB1 and CUL4 associated factor 17,nucleus|membrane|integral component of membrane|Cul4-RING E3 ubiquitin ligase complex|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.809,0,0,-1.5,1.6
ENSMUSG00000039252,LGI2,"leucine-rich repeat LGI family, member 2",cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.1,0.109,10,0,0,0,0,0,0.809,0,0,-1.7,1.3
ENSMUSG00000021182,CCDC88C,coiled-coil domain containing 88C,None,regulation of protein phosphorylation|Wnt signaling pathway|protein destabilization|protein homooligomerization|,protein binding|PDZ domain binding|protein self-association|,10,-0.1,0.439,10,0,0,0,0,0,0.809,0,0,-1.9,1.1
ENSMUSG00000051403,PPP1R37,"protein phosphatase 1, regulatory subunit 37",cellular_component|,negative regulation of phosphatase activity|,protein phosphatase inhibitor activity|phosphatase binding|,10,-0.7,25.5,10,-0.7,14.3,-0.7,39.4,-39.4,1.00E-05,1,1,-1,-0.5
ENSMUSG00000030165,KLRD1,"killer cell lectin-like receptor, subfamily D, member 1",external side of plasma membrane|membrane|integral component of membrane|,None,carbohydrate binding|,10,-0.9,6.57,10,-2,26.3,-1.8,29.1,-29.1,4.00E-05,1,1,-3.2,-0.6
ENSMUSG00000007036,ABHD16A,abhydrolase domain containing 16A,membrane|integral component of membrane|,None,GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,1.7,29.7,10,0.5,2.77,1.7,28.5,28.5,4.00E-05,1,1,0.9,2.8
ENSMUSG00000051207,MRGPRD,"MAS-related GPR, member D",extracellular space|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,9,-1.6,24.6,10,-0.5,5.34,-0.6,27.1,-27.1,7.00E-05,1,1,-2,-0.4
ENSMUSG00000022940,PIGP,"phosphatidylinositol glycan anchor biosynthesis, class P",glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex|endoplasmic reticulum|membrane|integral component of membrane|,GPI anchor biosynthetic process|,"transferase activity|transferase activity, transferring glycosyl groups|phosphatidylinositol N-acetylglucosaminyltransferase activity|",9,-1.8,26.8,9,0.5,2.33,-1.7,25.3,-25.3,0.00014,0,1,-3,-0.6
ENSMUSG00000022126,IRG1,immunoresponsive gene 1,mitochondrion|,immune system process|positive regulation of antimicrobial humoral response|positive regulation of antimicrobial humoral response|defense response|defense response|inflammatory response|embryo implantation|metabolic process|metabolic process|propionate catabolic process|negative regulation of NF-kappaB transcription factor activity|negative regulation of type I interferon production|response to lipopolysaccharide|negative regulation of toll-like receptor 2 signaling pathway|negative regulation of toll-like receptor 4 signaling pathway|cellular response to interferon-beta|innate immune response|negative regulation of innate immune response|negative regulation of inflammatory response|cellular response to molecule of bacterial origin|cellular response to lipopolysaccharide|cellular response to lipopolysaccharide|cellular response to interferon-gamma|cellular response to interleukin-1|cellular response to tumor necrosis factor|cellular response to progesterone stimulus|tolerance induction to lipopolysaccharide|tolerance induction to lipopolysaccharide|positive regulation of reactive oxygen species metabolic process|,lyase activity|2-methylcitrate dehydratase activity|aconitate decarboxylase activity|aconitate decarboxylase activity|,10,0.9,10.6,10,0.9,14.4,0.9,24.6,24.6,0.0002,0,1,0.5,1.3
ENSMUSG00000041700,LHFPL1,lipoma HMGIC fusion partner-like 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.6,2.46,10,2,27.1,1.9,24.2,24.2,0.00026,0,1,1.3,4
ENSMUSG00000064065,IPCEF1,interaction protein for cytohesin exchange factors 1,cytoplasm|cytosol|plasma membrane|membrane|,positive regulation of GTP catabolic process|,protein domain specific binding|,10,1.3,1.04,10,1.8,24,1.8,24,24,0.00026,0,1,1.1,3.7
ENSMUSG00000063582,OLFR666,olfactory receptor 666,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.96,10,1.4,25.6,1.4,22.4,22.4,0.00064,0,0,0.3,2.7
ENSMUSG00000033044,DHRS7C,dehydrogenase/reductase (SDR family) member 7C,extracellular region|longitudinal sarcoplasmic reticulum|sarcoplasmic reticulum membrane|,metabolic process|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|oxidation-reduction process|,"retinol dehydrogenase activity|oxidoreductase activity|pinocarveol dehydrogenase activity|chloral hydrate dehydrogenase activity|hydroxymethylmethylsilanediol oxidase activity|1-phenylethanol dehydrogenase activity|myrtenol dehydrogenase activity|cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity|3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity|2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity|cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity|citronellol dehydrogenase activity|naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity|2,4,4-trimethyl-1-pentanol dehydrogenase activity|2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity|1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity|endosulfan diol dehydrogenase activity|endosulfan hydroxyether dehydrogenase activity|3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity|3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity|versicolorin reductase activity|ketoreductase activity|",10,0.1,0.466,10,1.6,24.2,1.6,21.5,21.5,0.0011,0,0,0.6,3
ENSMUSG00000066748,OLFR145,olfactory receptor 145,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.562,10,-1.8,24.3,-1.8,21,-21,0.00139,0,0,-3,-0.4
ENSMUSG00000049100,PCDH10,protocadherin 10,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|,None,10,-0.2,0.667,10,1.6,24.1,1.6,20.8,20.8,0.00156,0,0,0.8,3
ENSMUSG00000045215,ASXL3,additional sex combs like 3 (Drosophila),cellular_component|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|DNA binding|metal ion binding|,10,-1.8,23,10,0.1,0.183,-1.8,19.8,-19.8,0.00264,0,0,-3,-0.8
ENSMUSG00000024283,WAC,WW domain containing adaptor with coiled-coil,nucleus|spliceosomal complex|,"transcription, DNA-templated|regulation of transcription, DNA-templated|cellular response to DNA damage stimulus|histone monoubiquitination|positive regulation of macroautophagy|chromatin modification|negative regulation of proteasomal ubiquitin-dependent protein catabolic process|G1 DNA damage checkpoint|positive regulation of transcription, DNA-templated|histone H2B conserved C-terminal lysine ubiquitination|",RNA polymerase II core binding|chromatin binding|,10,0.8,15.9,10,0.6,4.82,0.7,19.7,19.7,0.00278,0,0,0.4,1.3
ENSMUSG00000090369,4933411K16RIK,RIKEN cDNA 4933411K16 gene,cellular_component|,biological_process|,molecular_function|,10,-1.5,13.6,10,-0.7,6.83,-0.7,18.3,-18.3,0.00458,0,0,-1.8,-0.4
ENSMUSG00000031879,FAM96B,"family with sequence similarity 96, member B",nucleus|cytoplasm|spindle|cytoskeleton|MMXD complex|CIA complex|,chromosome segregation|,molecular_function|,7,0.7,17.2,7,0.4,2.12,0.7,17.8,17.8,0.00467,0,0,0.4,1.4
ENSMUSG00000024446,RPP21,ribonuclease P 21 subunit,cellular_component|nucleus|,tRNA processing|biological_process|,molecular_function|ribonuclease P activity|hydrolase activity|metal ion binding|,7,1,18.7,7,0,0,1,16.8,16.8,0.00489,0,0,0.6,1.8
ENSMUSG00000043453,MAGEA10,"melanoma antigen family A, 10",cellular_component|,biological_process|,molecular_function|,10,-1,8.39,10,-0.6,7.84,-0.7,14.9,-14.9,0.0057,0,0,-1.4,-0.4
ENSMUSG00000057531,DTNBP1,dystrobrevin binding protein 1,intracellular|cell|nucleus|cytoplasm|endosome|endoplasmic reticulum|endoplasmic reticulum membrane|plasma membrane|postsynaptic density|postsynaptic density|membrane|sarcoplasm|cell junction|axon|growth cone|synaptic vesicle membrane|synaptic vesicle membrane|BLOC-1 complex|BLOC-1 complex|cytoplasmic vesicle|sarcolemma|neuron projection|dendritic spine|synapse|postsynaptic membrane|,positive regulation of neurotransmitter secretion|organelle organization|muscle organ development|blood coagulation|anterograde axon cargo transport|positive regulation of gene expression|regulation of dopamine secretion|neuron projection development|neuron projection development|actin cytoskeleton reorganization|anterograde synaptic vesicle transport|neuron projection morphogenesis|response to stimulus|platelet dense granule organization|regulation of dopamine receptor signaling pathway|,protein binding|,10,0.8,10.3,10,0.7,5.08,0.7,14.9,14.9,0.0057,0,0,0.3,1.3
ENSMUSG00000038770,KPNA7,karyopherin alpha 7 (importin alpha 8),cellular_component|nucleus|cytoplasm|,protein import into nucleus|transport|biological_process|protein transport|,protein transporter activity|,10,-0.4,3.75,10,1.4,18.1,1.4,14.7,14.7,0.00578,0,0,0.6,3
ENSMUSG00000047343,METTL21C,methyltransferase like 21C,cellular_component|nucleus|,protein methylation|peptidyl-lysine methylation|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.5,3.01,10,1.3,17.4,1.3,14.2,14.2,0.00611,0,0,0.3,2.6
ENSMUSG00000046456,TMEM150B,transmembrane protein 150B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.8,17.6,10,-0.2,0.807,1.8,14.1,14.1,0.00619,0,0,0.3,3
ENSMUSG00000070814,6330408A02RIK,RIKEN cDNA 6330408A02 gene,cellular_component|nucleus|,hematopoietic progenitor cell differentiation|ubiquitin-dependent protein catabolic process|multicellular organismal development|,molecular_function|,10,0,0,10,1.4,17.1,1.4,13.6,13.6,0.00647,0,0,0.6,3
ENSMUSG00000018449,RPAIN,RPA interacting protein,nucleus|nucleolus|cytoplasm|PML body|,DNA-dependent DNA replication|DNA repair|DNA recombination|protein import into nucleus|response to UV|,protein complex binding|metal ion binding|,10,-0.1,0.788,10,1.3,16.5,1.3,13.4,13.4,0.00654,0,0,0.3,2.9
ENSMUSG00000021730,HCN1,"hyperpolarization-activated, cyclic nucleotide-gated K+ 1",plasma membrane|integral component of plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|axon|dendrite|,transport|ion transport|potassium ion transport|sodium ion transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|apical protein localization|retinal cone cell development|transmembrane transport|cellular response to cAMP|cellular response to cAMP|potassium ion transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,nucleotide binding|ion channel activity|intracellular cAMP activated cation channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|potassium channel activity|sodium channel activity|protein binding|cAMP binding|identical protein binding|,10,0.8,15.9,10,0,0,0.8,12.9,12.9,0.00687,0,0,0.4,1.5
ENSMUSG00000036196,SLC26A8,"solute carrier family 26, member 8",plasma membrane|membrane|integral component of membrane|,transport|ion transport|anion transport|chloride transport|meiotic nuclear division|multicellular organismal development|spermatogenesis|sulfate transport|oxalate transport|cell differentiation|sulfate transmembrane transport|chloride transmembrane transport|,chloride channel activity|sulfate transmembrane transporter activity|anion:anion antiporter activity|oxalate transmembrane transporter activity|,10,0.9,3.83,10,0.6,9.79,0.6,12.9,12.9,0.00687,0,0,0.3,1.3
ENSMUSG00000045871,SLITRK6,"SLIT and NTRK-like family, member 6",plasma membrane|integral component of plasma membrane|cell surface|membrane|integral component of membrane|cell periphery|,startle response|lens development in camera-type eye|auditory receptor cell morphogenesis|axonogenesis|synapse assembly|synapse assembly|visual perception|sensory perception of sound|adult locomotory behavior|vestibulocochlear nerve development|auditory behavior|multicellular organism growth|inner ear morphogenesis|camera-type eye development|neuron projection morphogenesis|response to stimulus|vestibular reflex|linear vestibuloocular reflex|innervation|cochlea development|,molecular_function|,10,-0.3,2.4,10,1.3,14.4,1.3,12.6,12.6,0.00707,0,0,0.7,2.9
ENSMUSG00000078317,F8A,factor 8-associated gene A,nucleus|,biological_process|,molecular_function|,10,-0.5,10.4,10,-1.3,3.49,-0.6,12.5,-12.5,0.00712,0,0,-1.5,-0.3
ENSMUSG00000059488,OLFR727,olfactory receptor 727,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,1.4,15.5,1.4,12.1,12.1,0.00749,0,0,0.5,3
ENSMUSG00000020522,MFAP3,microfibrillar-associated protein 3,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.5,8.36,10,0.3,4.47,0.4,11.8,11.8,0.00776,0,0,0.2,0.8
ENSMUSG00000034159,2310007B03RIK,RIKEN cDNA 2310007B03 gene,cellular_component|,biological_process|,molecular_function|,9,-0.7,5.48,9,1.3,13.3,0.3,11.8,11.8,0.00776,0,0,0.2,2.5
ENSMUSG00000045822,ZSWIM3,zinc finger SWIM-type containing 3,cellular_component|,biological_process|,zinc ion binding|metal ion binding|,10,-0.6,5.45,10,-0.6,6.64,-0.6,11.7,-11.7,0.00785,0,0,-1.1,-0.2
ENSMUSG00000037185,KRT80,keratin 80,cytoplasm|intermediate filament|keratin filament|,None,structural molecule activity|,10,-0.3,0.532,10,-1.6,12.5,-1.5,10.8,-10.8,0.00867,0,0,-3,-0.4
ENSMUSG00000042993,IFNK,interferon kappa,extracellular region|extracellular space|,"adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|regulation of transcription, DNA-templated|defense response|humoral immune response|cytokine-mediated signaling pathway|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|",cytokine activity|cytokine receptor binding|type I interferon receptor binding|type I interferon receptor binding|,9,0.5,5.73,10,0.6,5.34,0.5,10.5,10.5,0.00889,0,0,0.2,1.1
ENSMUSG00000085576,DPY19L2,dpy-19-like 2 (C. elegans),nucleus|nuclear inner membrane|membrane|integral component of membrane|,multicellular organismal development|spermatogenesis|spermatid development|spermatid development|cell differentiation|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.6,10.9,10,0.2,1.24,-0.6,10.3,-10.3,0.00905,0,0,-1.2,-0.2
ENSMUSG00000048933,OLFR722,olfactory receptor 722,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1.3,7.69,10,-1.4,2.49,-1.3,9.8,-9.8,0.00974,0,0,-2.7,-0.7
ENSMUSG00000038305,SPATS2L,"spermatogenesis associated, serine-rich 2-like",nucleus|nucleolus|cytoplasm|protein complex|,biological_process|,poly(A) RNA binding|,10,0.8,12.4,10,-0.2,0.396,0.8,9.65,9.65,0.0101,0,0,0.4,1.8
ENSMUSG00000019894,SLC6A15,"solute carrier family 6 (neurotransmitter transporter), member 15",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|neurotransmitter transport|amino acid transport|neutral amino acid transport|neutral amino acid transport|leucine transport|proline transport|proline transmembrane transport|sodium ion transmembrane transport|L-alpha-amino acid transmembrane transport|,proline:sodium symporter activity|neurotransmitter:sodium symporter activity|symporter activity|,10,0.5,8.33,10,0.4,1.93,0.5,9.63,9.63,0.0101,0,0,0.2,1.1
ENSMUSG00000060057,OLFR193,olfactory receptor 193,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.6,7.45,10,0.9,2.72,0.8,9.53,9.53,0.0103,0,0,-0.9,2
ENSMUSG00000073991,CNBD1,cyclic nucleotide binding domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.8,10.5,10,-0.8,1.19,0.8,8.95,8.95,0.0115,0,0,0.2,1.6
ENSMUSG00000056313,1810011O10RIK,RIKEN cDNA 1810011O10 gene,cellular_component|,apoptotic process|biological_process|,molecular_function|,10,-1,10.1,10,0.6,3.14,-0.8,8.86,-8.86,0.0117,0,0,-1.7,-0.2
ENSMUSG00000026312,CDH7,"cadherin 7, type 2",plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|,calcium ion binding|metal ion binding|,10,-0.6,4.14,10,-0.9,5.68,-0.7,8.78,-8.78,0.0119,0,0,-2,0.4
ENSMUSG00000036168,CCDC38,coiled-coil domain containing 38,cellular_component|,biological_process|,molecular_function|,10,-0.6,5.29,10,-1.2,4.28,-0.6,8.63,-8.63,0.0122,0,0,-1.7,-0.3
ENSMUSG00000037461,INTS7,integrator complex subunit 7,nucleus|chromosome|integrator complex|,DNA damage checkpoint|cellular response to DNA damage stimulus|snRNA processing|cellular response to ionizing radiation|,molecular_function|,10,0.5,7.75,9,0.6,1.16,0.5,8.63,8.63,0.0122,0,0,0.2,1.2
ENSMUSG00000040111,GRAMD1B,GRAM domain containing 1B,membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.5,6.66,10,-0.3,2.57,-0.6,8.53,-8.53,0.0125,0,0,-1.2,-0.1
ENSMUSG00000029843,SLC13A4,"solute carrier family 13 (sodium/sulfate symporters), member 4",cellular_component|,biological_process|,molecular_function|,10,-0.7,5.54,10,0.8,9.3,0.7,8.5,8.5,0.0126,0,0,-0.6,2
ENSMUSG00000050239,KRTAP24-1,keratin associated protein 24-1,cellular_component|,biological_process|,molecular_function|,10,-1.3,7.58,10,-1.3,1.13,-1.3,8.44,-8.44,0.0127,0,0,-2,-0.6
ENSMUSG00000063615,OLFR64,olfactory receptor 64,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,6.57,10,-0.6,2.17,-0.5,8.4,-8.4,0.0128,0,0,-1.5,1
ENSMUSG00000074111,MRGPRA9,"MAS-related GPR, member A9",cellular_component|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,1,3.45,10,-0.6,7.32,-0.4,8.21,-8.21,0.0135,0,0,-1.8,0.4
ENSMUSG00000053062,JAM2,junction adhesion molecule 2,plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,negative regulation of cell adhesion|,protein heterodimerization activity|,10,0.8,0.0965,10,0.7,8.36,0.7,8.2,8.2,0.0135,0,0,0.3,1.7
ENSMUSG00000030147,CLEC4B1,"C-type lectin domain family 4, member b1",None,positive regulation of release of sequestered calcium ion into cytosol|,None,10,-0.2,1.42,10,0.9,9.1,0.6,8.19,8.19,0.0135,0,0,0.2,1.6
ENSMUSG00000037973,CCDC129,coiled-coil domain containing 129,cellular_component|,biological_process|,molecular_function|receptor binding|,10,0.8,5.51,10,0.8,2.95,0.8,8.12,8.12,0.0137,0,0,0.2,1.8
ENSMUSG00000036099,VEZT,"vezatin, adherens junctions transmembrane protein",stereocilia ankle link complex|nucleus|nucleus|cytoplasm|plasma membrane|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|,multicellular organismal development|single organismal cell-cell adhesion|chordate embryonic development|,protein binding|myosin binding|,10,0.3,0.88,10,0.9,8.29,0.8,8.09,8.09,0.0138,0,0,0.3,1.7
ENSMUSG00000063764,OLFR508,olfactory receptor 508,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,6.36,10,-0.9,2.72,-0.6,8.05,-8.05,0.0139,0,0,-1.5,-0.2
ENSMUSG00000050957,INSL6,insulin-like 6,extracellular region|,spermatogenesis|spermatid development|male gonad development|fertilization|sperm motility|negative regulation of apoptotic process|,hormone activity|,10,-1.6,10.8,10,-0.2,0.4,-1.5,8.03,-8.03,0.0139,0,0,-3,-0.5
ENSMUSG00000067524,OLFR1428,olfactory receptor 1428,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1.6,9.99,10,0.4,3.59,-1.5,7.93,-7.93,0.0143,0,0,-3,-0.2
ENSMUSG00000020633,DCDC2C,doublecortin domain containing 2C,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|,10,0.6,7.99,10,0.2,0.257,0.5,7.92,7.92,0.0143,0,0,0.2,1.3
ENSMUSG00000042401,CRTAC1,cartilage acidic protein 1,extracellular region|proteinaceous extracellular matrix|growth cone|,axonal fasciculation|olfactory bulb development|negative regulation of receptor binding|,calcium ion binding|protein binding|,10,1.2,3.52,10,-1.4,10.2,-1.3,7.84,-7.84,0.0146,0,0,-3,-0.5
ENSMUSG00000090629,OLFR180,olfactory receptor 180,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,3.23,10,1.3,7.83,0.3,7.83,7.83,0.0147,0,0,0.1,1.8
ENSMUSG00000033149,PHLDB2,"pleckstrin homology-like domain, family B, member 2",cytoplasm|plasma membrane|membrane|intermediate filament cytoskeleton|,biological_process|,molecular_function|,10,0.4,2.91,10,0.8,5.94,0.5,7.79,7.79,0.0148,0,0,0.1,1.4
ENSMUSG00000022790,IGSF11,"immunoglobulin superfamily, member 11",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|regulation of growth|,None,10,-0.7,10.3,10,0.5,1.73,-0.7,7.74,-7.74,0.015,0,0,-1.9,-0.1
ENSMUSG00000043020,WDR63,WD repeat domain 63,cellular_component|,biological_process|,molecular_function|,10,-1.3,3.97,10,-0.5,6.24,-0.5,7.71,-7.71,0.0151,0,0,-1.7,-0.1
ENSMUSG00000026237,NMUR1,neuromedin U receptor 1,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,calcium ion transport|chloride transport|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|activation of phospholipase C activity|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|calcium-mediated signaling|inositol phosphate-mediated signaling|,neuromedin U receptor activity|signal transducer activity|G-protein coupled receptor activity|neuropeptide receptor activity|,9,-0.1,0.0154,10,1.1,10.7,1.1,7.63,7.63,0.0153,0,0,0.2,1.9
ENSMUSG00000042942,GREB1L,growth regulation by estrogen in breast cancer-like,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,10.4,10,-0.5,5.83,0.7,7.63,7.63,0.0153,0,0,-0.8,2
ENSMUSG00000048356,OLFR1496,olfactory receptor 1496,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.9,5.9,10,0.6,2.18,0.6,7.58,7.58,0.0154,0,0,0.2,1.6
ENSMUSG00000030205,GPRC5D,"G protein-coupled receptor, family C, group 5, member D",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|keratinization|hair cycle|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,1.1,6.73,10,1,0.996,1.1,7.32,7.32,0.0165,0,0,0.4,2
ENSMUSG00000047508,MBD3L2,methyl-CpG binding domain protein 3-like 2,cellular_component|,biological_process|,molecular_function|,10,0.5,4.63,10,0.5,2.94,0.5,7.24,7.24,0.0168,0,0,0.1,1.3
ENSMUSG00000051860,SAMD7,sterile alpha motif domain containing 7,cellular_component|,biological_process|,molecular_function|,10,-0.4,3.29,10,-0.5,4.36,-0.5,7.23,-7.23,0.0168,0,0,-1.1,-0.1
ENSMUSG00000054641,MMRN1,multimerin 1,cellular_component|extracellular region|,biological_process|,molecular_function|,9,-0.4,6.78,9,-1.1,2.03,-0.4,7.14,-7.14,0.0171,0,0,-1.5,-0.1
ENSMUSG00000071909,GM806,predicted gene 806,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.735,10,-0.6,7.07,-0.5,7.14,-7.14,0.0171,0,0,-1.2,-0.1
ENSMUSG00000094120,GM3233,predicted gene 3233,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.6,6.12,10,0.8,5.94,0.5,7.13,7.13,0.0171,0,0,-1.3,1.9
ENSMUSG00000069132,NXPH2,neurexophilin 2,extracellular region|,None,receptor binding|,10,0.4,3.94,10,0.5,3.88,0.4,7.01,7.01,0.0179,0,0,0,1.1
ENSMUSG00000030217,ART4,ADP-ribosyltransferase 4,cellular_component|plasma membrane|membrane|integral component of membrane|anchored component of membrane|,protein ADP-ribosylation|biological_process|,"molecular_function|NAD(P)+-protein-arginine ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.8,10,10,0.4,2.85,-0.8,7,-7,0.0179,0,0,-2,0.1
ENSMUSG00000047025,CCER1,coiled coil glutamate rich protein 1,cellular_component|,biological_process|,molecular_function|,10,-1,9.42,10,0.3,0.509,-0.7,6.98,-6.98,0.018,0,0,-1.9,-0.1
ENSMUSG00000057037,CFHR1,complement factor H-related 1,extracellular vesicular exosome|blood microparticle|,biological_process|,molecular_function|,10,0.4,2.94,10,0.4,4.3,0.4,6.92,6.92,0.0184,0,0,0,1.2
ENSMUSG00000041809,EFHC1,EF-hand domain (C-terminal) containing 1,cilium|axoneme|neuronal cell body|,cellular calcium ion homeostasis|positive regulation of apoptotic process|,calcium ion binding|protein C-terminus binding|,10,-0.6,7.52,10,-0.2,0.778,-0.5,6.91,-6.91,0.0184,0,0,-1.4,-0.1
ENSMUSG00000043311,D17H6S53E,"DNA segment, Chr 17, human D6S53E",cytoplasm|,biological_process|,molecular_function|,10,-0.4,2.89,10,-0.5,4.42,-0.4,6.91,-6.91,0.0184,0,0,-1.1,0
ENSMUSG00000031875,CMTM3,CKLF-like MARVEL transmembrane domain containing 3,extracellular space|cytoplasm|membrane|integral component of membrane|nuclear membrane|,chemotaxis|positive regulation of B cell receptor signaling pathway|,cytokine activity|protein binding|,10,0.3,3.63,10,-1.4,9.22,-0.8,6.86,-6.86,0.0188,0,0,-2.9,-0.1
ENSMUSG00000059956,SERPINB12,"serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12",extracellular space|cytoplasm|extracellular vesicular exosome|,hematopoietic progenitor cell differentiation|negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,1.1,7.01,10,0.7,0.441,1,6.84,6.84,0.0189,0,0,0.3,2
ENSMUSG00000096695,OLFR196,olfactory receptor 196,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.9,6.15,10,-1.5,9.83,-1.5,6.78,-6.78,0.0192,0,0,-3,1.1
ENSMUSG00000073721,GM13125,predicted gene 13125,cellular_component|,biological_process|,molecular_function|,10,0.5,5.52,10,0.3,2.4,0.4,6.64,6.64,0.0202,0,0,0,1.1
ENSMUSG00000055937,KRT28,keratin 28,cytoplasm|intermediate filament|,biological_process|,structural molecule activity|,10,0.8,5.15,10,0.4,2.43,0.5,6.64,6.64,0.0202,0,0,0.1,1.7
ENSMUSG00000047658,GAL3ST3,galactose-3-O-sulfotransferase 3,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biosynthetic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|galactosylceramide sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0.3,1.16,10,-0.8,8.82,-0.8,6.6,-6.6,0.0204,0,0,-1.8,-0.1
ENSMUSG00000074647,FAM83C,"family with sequence similarity 83, member C",cellular_component|,biological_process|,molecular_function|,10,-0.4,2.38,10,-0.9,5.04,-0.5,6.51,-6.51,0.0209,0,0,-1.6,-0.1
ENSMUSG00000011154,1700026D08RIK,RIKEN cDNA 1700026D08 gene,cellular_component|membrane|,biological_process|,molecular_function|,10,-0.4,1.64,10,-0.8,5.33,-0.7,6.5,-6.5,0.0209,0,0,-1.8,-0.1
ENSMUSG00000026963,TMEM210,transmembrane protein 210,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.813,10,-0.5,6.45,-0.5,6.48,-6.48,0.0211,0,0,-1.4,0.2
ENSMUSG00000018068,INTS2,integrator complex subunit 2,intracellular|nucleus|membrane|membrane|integral component of membrane|integrator complex|,snRNA processing|,molecular_function|,10,0.8,3.56,10,-1.1,4.11,-1.3,6.47,-6.47,0.0211,0,0,-3,0.7
ENSMUSG00000030617,CCDC83,coiled-coil domain containing 83,cellular_component|,biological_process|,molecular_function|,10,0.4,2.49,10,0.6,4.43,0.6,6.4,6.4,0.0216,0,0,-1.2,1.5
ENSMUSG00000040541,TMEM225,transmembrane protein 225,cellular_component|membrane|integral component of membrane|,negative regulation of phosphatase activity|,molecular_function|,10,0.5,5.45,10,0.8,1.95,0.5,6.37,6.37,0.0218,0,0,0.1,1.5
ENSMUSG00000031576,KCNU1,"potassium channel, subfamily U, member 1",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|calcium-activated potassium channel activity|large conductance calcium-activated potassium channel activity|,10,-0.5,8.74,10,0.5,6.13,-0.5,6.37,-6.37,0.0218,0,0,-1.3,0.8
ENSMUSG00000023802,NOX3,NADPH oxidase 3,cytoplasm|membrane|integral component of membrane|NADPH oxidase complex|extracellular vesicular exosome|,temperature homeostasis|detection of gravity|response to gravity|superoxide anion generation|otolith development|oxidation-reduction process|,protein binding|superoxide-generating NADPH oxidase activity|oxidoreductase activity|,10,-0.5,4.95,10,-0.5,1.62,-0.5,6.27,-6.27,0.0225,0,0,-1.3,0
ENSMUSG00000021790,DYDC1,DPY30 domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-1.6,9.4,10,0,0,-1.6,6.17,-6.17,0.0232,0,0,-3,-0.3
ENSMUSG00000044067,GPR22,G protein-coupled receptor 22,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.1,0.259,10,0.7,6.62,0.7,6.15,6.15,0.0233,0,0,0.1,1.6
ENSMUSG00000035004,IGSF6,"immunoglobulin superfamily, member 6",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,3.67,10,0.7,2.75,0.7,6.11,6.11,0.0236,0,0,0.1,1.7
ENSMUSG00000096380,GM19668,"predicted gene, 19668",intermediate filament|,None,None,10,-0.1,0.353,10,0.8,8.42,0.7,6.1,6.1,0.0238,0,0,0.2,1.9
ENSMUSG00000096169,GM4461,predicted gene 4461,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|,10,-1.1,2.52,10,-1.1,3.84,-1.1,6.05,-6.05,0.0241,0,0,-2,-0.2
ENSMUSG00000073551,SPINK13,"serine peptidase inhibitor, Kazal type 13",cellular_component|extracellular region|,biological_process|negative regulation of peptidase activity|negative regulation of acrosome reaction|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,9,0.5,7.17,9,0,0,0.5,6,6,0.0246,0,0,0,1.4
ENSMUSG00000047261,GAP43,growth associated protein 43,cytoplasm|plasma membrane|plasma membrane|membrane|cell junction|axon|filopodium membrane|cell projection|synapse|cell periphery|,multicellular organismal development|nervous system development|axon guidance|glial cell differentiation|axon choice point recognition|cell differentiation|regulation of growth|cell fate commitment|regulation of filopodium assembly|,calmodulin binding|,10,0.9,8.33,10,0,0,0.8,5.97,5.97,0.0248,0,0,-1.1,2
ENSMUSG00000079429,MROH2A,maestro heat-like repeat family member 2A,cellular_component|,biological_process|,molecular_function|,10,0.4,6.56,10,0,0,0.4,5.89,5.89,0.0254,0,0,-0.3,1.1
ENSMUSG00000020419,HORMAD2,HORMA domain containing 2,nucleus|chromosome|,meiotic nuclear division|meiotic sister chromatid cohesion|,protein binding|,10,-1,6.47,10,1,1.48,-0.9,5.82,-5.82,0.026,0,0,-2,0.1
ENSMUSG00000074063,OSGIN1,oxidative stress induced growth inhibitor 1,cellular_component|,negative regulation of cell growth|,growth factor activity|,10,-0.4,4.51,10,-0.4,1.59,-0.4,5.82,-5.82,0.026,0,0,-1.2,0
ENSMUSG00000046178,NXPH1,neurexophilin 1,extracellular region|,None,receptor binding|,10,-0.7,8.26,10,0.3,1.04,-0.7,5.81,-5.81,0.0261,0,0,-1.9,-0.1
ENSMUSG00000090053,PALM2,paralemmin 2,cellular_component|,biological_process|,molecular_function|,10,-1.1,5.21,10,1.2,4.45,-0.7,5.78,-5.78,0.0264,0,0,-2,1.4
ENSMUSG00000042357,GJB5,"gap junction protein, beta 5",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,cell communication|spongiotrophoblast differentiation|labyrinthine layer morphogenesis|,None,10,0.7,6.19,10,-0.1,0.225,0.6,5.78,5.78,0.0264,0,0,-0.7,1.7
ENSMUSG00000017176,NT5C3B,"5'-nucleotidase, cytosolic IIIB",cellular_component|cytoplasm|,biological_process|nucleotide metabolic process|,nucleotide binding|magnesium ion binding|molecular_function|5'-nucleotidase activity|hydrolase activity|metal ion binding|,10,0.6,8.26,10,0,0,0.6,5.75,5.75,0.0268,0,0,0,1.6
ENSMUSG00000070875,OLFR1100,olfactory receptor 1100,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.6,6.7,10,0.2,1.16,-0.5,5.7,-5.7,0.0273,0,0,-1.4,0.2
ENSMUSG00000066189,CACNG3,"calcium channel, voltage-dependent, gamma subunit 3",membrane|integral component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,voltage-gated ion channel activity|calcium channel activity|,10,-1,0.185,10,0.5,7.08,0.4,5.69,5.69,0.0274,0,0,-0.2,1.5
ENSMUSG00000070378,OLFR403,olfactory receptor 403,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.7,3.5,10,0.5,2.89,0.6,5.69,5.69,0.0274,0,0,-0.2,1.5
ENSMUSG00000063193,CD300LB,CD300 antigen like family member B,plasma membrane|membrane|integral component of membrane|,immune system process|neutrophil mediated immunity|positive regulation of mast cell activation|cellular response to lipopolysaccharide|,protein binding|,10,1.4,5.01,10,1,1.46,1.3,5.65,5.65,0.0279,0,0,0.6,3
ENSMUSG00000038740,MVB12B,multivesicular body subunit 12B,ESCRT I complex|nucleus|endosome|early endosome|late endosome|cytosol|plasma membrane|membrane|vesicle|extracellular vesicular exosome|,transport|protein transport|regulation of epidermal growth factor receptor signaling pathway|,lipid binding|,9,0.7,7.27,9,-0.4,2.34,0.6,5.63,5.63,0.0282,0,0,-0.5,1.7
ENSMUSG00000045036,TMEM232,transmembrane protein 232,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.251,10,-1.5,8.54,-1.4,5.6,-5.6,0.0285,0,0,-2.8,-0.1
ENSMUSG00000063376,IFNA13,interferon alpha 13,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,10,0.5,6.7,10,-0.5,1.83,0.5,5.58,5.58,0.0287,0,0,-0.7,1.3
ENSMUSG00000013643,LYPD8,LY6/PLAUR domain containing 8,cellular_component|plasma membrane|membrane|anchored component of membrane|,biological_process|,molecular_function|,10,0.5,7.77,10,-0.8,0.0504,0.5,5.56,5.56,0.0289,0,0,-0.3,1.6
ENSMUSG00000095667,OLFR854,olfactory receptor 854,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.88,10,0.4,4.38,0.3,5.51,5.51,0.0294,0,0,-0.3,1.1
ENSMUSG00000064121,OLFR96,olfactory receptor 96,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,6.77,10,0.5,5.22,-0.4,5.45,-5.45,0.0301,0,0,-1.1,1
ENSMUSG00000050164,MCHR1,melanin-concentrating hormone receptor 1,plasma membrane|plasma membrane|membrane|integral component of membrane|nonmotile primary cilium|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|positive regulation of calcium ion transport|regulation of feeding behavior|,signal transducer activity|G-protein coupled receptor activity|protein C-terminus binding|melanin-concentrating hormone receptor activity|hormone binding|,10,-0.6,4.15,10,-1,2.22,-0.7,5.4,-5.4,0.0307,0,0,-1.9,-0.1
ENSMUSG00000094913,GM9507,predicted gene 9507,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,1,4.03,10,0.8,1.9,0.9,5.38,5.38,0.031,0,0,0.2,2
ENSMUSG00000029005,DRAXIN,dorsal inhibitory axon guidance protein,extracellular region|,multicellular organismal development|axon guidance|Wnt signaling pathway|dorsal spinal cord development|commissural neuron differentiation in spinal cord|negative regulation of axon extension|forebrain development|negative regulation of neuron apoptotic process|negative regulation of canonical Wnt signaling pathway|,protein binding|,10,1,2.61,10,0.5,4.2,0.6,5.38,5.38,0.031,0,0,0.1,1.8
ENSMUSG00000038248,SOBP,sine oculis-binding protein homolog (Drosophila),None,sensory perception of sound|locomotory behavior|inner ear morphogenesis|,SUMO polymer binding|metal ion binding|,10,-0.5,3.75,10,-0.9,2.44,-0.6,5.36,-5.36,0.0312,0,0,-1.9,0
ENSMUSG00000038709,TXNDC8,thioredoxin domain containing 8,acrosomal vesicle|acrosomal vesicle|cytoplasm|Golgi apparatus|Golgi apparatus|sperm flagellum|extracellular vesicular exosome|,glycerol ether metabolic process|multicellular organismal development|spermatogenesis|cell differentiation|cell redox homeostasis|,protein disulfide oxidoreductase activity|,10,0.4,3.5,10,0.6,2.37,0.5,5.34,5.34,0.0315,0,0,-0.3,1.3
ENSMUSG00000048004,TMEM196,transmembrane protein 196,cellular_component|,biological_process|,molecular_function|,10,0.5,2.83,10,1.1,4.35,0.6,5.33,5.33,0.0316,0,0,-1.1,2
ENSMUSG00000026668,UCMA,upper zone of growth plate and cartilage matrix associated,extracellular region|proteinaceous extracellular matrix|extracellular space|cytoplasm|Golgi apparatus|cytoskeleton|aggresome|extracellular matrix|perinuclear region of cytoplasm|,negative regulation of osteoblast differentiation|,molecular_function|,10,-0.5,2,10,0.5,4.22,0.5,5.27,5.27,0.0323,0,0,-0.7,1.4
ENSMUSG00000019767,CCDC170,coiled-coil domain containing 170,cellular_component|,biological_process|,molecular_function|,10,0.8,6.08,10,0,0,0.8,5.26,5.26,0.0325,0,0,-1.6,2
ENSMUSG00000055882,ABHD16B,abhydrolase domain containing 16B,cellular_component|,biological_process|,molecular_function|GPI-anchor transamidase activity|hydrolase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|,10,0.3,1.63,10,-0.8,7.89,-0.7,5.25,-5.25,0.0326,0,0,-1.9,0.4
ENSMUSG00000073574,GRXCR2,"glutaredoxin, cysteine rich 2",cellular_component|,biological_process|,molecular_function|heat shock protein binding|unfolded protein binding|,10,-0.6,5.69,10,-0.3,0.26,-0.5,5.25,-5.25,0.0326,0,0,-1.5,0
ENSMUSG00000014846,TPPP3,tubulin polymerization-promoting protein family member 3,cytoplasm|cytoskeleton|microtubule|extracellular vesicular exosome|,microtubule bundle formation|,tubulin binding|,10,-0.9,1.35,10,-0.6,4.33,-0.7,5.22,-5.22,0.033,0,0,-1.7,-0.1
ENSMUSG00000059974,NTM,neurotrimin,extracellular space|plasma membrane|cell surface|membrane|axon|anchored component of membrane|perinuclear region of cytoplasm|excitatory synapse|,cell adhesion|negative regulation of neuron projection development|,oligosaccharide binding|,10,-0.5,4.12,10,-0.4,1.43,-0.4,5.22,-5.22,0.033,0,0,-1.3,0.3
ENSMUSG00000044317,GPR4,G protein-coupled receptor 4,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0.5,3.93,10,0.8,1.83,0.6,5.22,5.22,0.033,0,0,-0.9,1.6
ENSMUSG00000067529,OLFR1423,olfactory receptor 1423,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.6,4.83,10,0.3,1.32,0.4,5.17,5.17,0.0337,0,0,-0.1,1.4
ENSMUSG00000054498,OLFR308,olfactory receptor 308,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1.2,4.14,10,-1.1,1.38,-1.2,5.16,-5.16,0.0338,0,0,-2,0.1
ENSMUSG00000062103,OLFR924,olfactory receptor 924,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.662,10,-0.8,5.12,-0.7,5.09,-5.09,0.0349,0,0,-1.9,-0.1
ENSMUSG00000093804,OLFR1303,olfactory receptor 1303,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,7.58,10,0,0,-0.5,4.98,-4.98,0.0365,0,0,-1.6,0.4
ENSMUSG00000055333,FAT2,FAT tumor suppressor homolog 2 (Drosophila),nucleus|plasma membrane|cell-cell adherens junction|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|epithelial cell migration|,calcium ion binding|,10,-0.5,4.88,10,-0.2,1.14,-0.4,4.98,-4.98,0.0365,0,0,-1.4,0.5
ENSMUSG00000029829,TMEM213,transmembrane protein 213,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.5,6.54,10,-0.1,0.176,-0.4,4.97,-4.97,0.0366,0,0,-1.4,0.1
ENSMUSG00000032226,GCNT3,"glucosaminyl (N-acetyl) transferase 3, mucin type",Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,immunoglobulin production in mucosal tissue|protein O-linked glycosylation|tissue morphogenesis|intestinal absorption|kidney morphogenesis|,"beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|",10,-0.4,4.59,10,-0.2,0.991,-0.4,4.93,-4.93,0.0372,0,0,-1.1,0.8
ENSMUSG00000044162,TNIP3,TNFAIP3 interacting protein 3,cellular_component|,MyD88-independent toll-like receptor signaling pathway|toll-like receptor 4 signaling pathway|negative regulation of I-kappaB kinase/NF-kappaB signaling|cellular response to lipopolysaccharide|,polyubiquitin binding|,10,-0.6,5.47,10,0.5,1.53,-0.3,4.88,-4.88,0.038,0,0,-1.4,0.8
ENSMUSG00000056586,ZAR1L,zygote arrest 1-like,cytoplasm|,biological_process|,protein binding|,10,-0.7,7.11,10,0.1,0.332,-0.7,4.81,-4.81,0.0393,0,0,-1.8,0.4
ENSMUSG00000051379,FLRT3,fibronectin leucine rich transmembrane protein 3,extracellular space|membrane|integral component of membrane|,axon guidance|negative chemotaxis|,protein binding|chemorepellent activity|,9,-1.1,7.85,9,0.6,1.41,-1.1,4.8,-4.8,0.0394,0,0,-2,0.5
ENSMUSG00000022696,SIDT1,"SID1 transmembrane family, member 1",cellular_component|membrane|integral component of membrane|,biological_process|dsRNA transport|,molecular_function|RNA transmembrane transporter activity|,10,1,3.86,10,0.6,1.96,0.7,4.8,4.8,0.0394,0,0,0.1,1.8
ENSMUSG00000058250,TAS2R138,"taste receptor, type 2, member 138",membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|bitter taste receptor activity|,10,-0.4,3.73,10,-0.8,1.5,-0.3,4.72,-4.72,0.0407,0,0,-1.5,0.1
ENSMUSG00000049799,LRRC19,leucine rich repeat containing 19,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.71,10,-0.4,3.21,-0.3,4.59,-4.59,0.0433,0,0,-1.1,0.6
ENSMUSG00000048572,TMEM252,transmembrane protein 252,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.6,4.75,10,-0.1,0.361,-0.6,4.59,-4.59,0.0433,0,0,-1.7,0
ENSMUSG00000035486,PLK5,polo-like kinase 5,nucleus|nucleolus|cytoplasm|,defense response to tumor cell|defense response to tumor cell|protein phosphorylation|transformed cell apoptotic process|transformed cell apoptotic process|cellular response to DNA damage stimulus|cell cycle|negative regulation of cell proliferation|negative regulation of cell proliferation|positive regulation of neuron projection development|positive regulation of neuron projection development|cell differentiation|G2 DNA damage checkpoint|cell division|cellular response to growth factor stimulus|regulation of G1/S transition of mitotic cell cycle|regulation of G1/S transition of mitotic cell cycle|,"nucleotide binding|protein kinase activity|protein serine/threonine kinase activity|ATP binding|transferase activity, transferring phosphorus-containing groups|metal ion binding|",10,-0.4,4.94,10,-0.2,0.452,-0.4,4.59,-4.59,0.0433,0,0,-1.2,0.2
ENSMUSG00000095498,IFNA1,interferon alpha 1,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|defense response to bacterium|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,9,-0.1,0.344,9,-0.5,4.74,-0.4,4.57,-4.57,0.0437,0,0,-1.3,0.3
ENSMUSG00000003279,DLGAP1,"discs, large (Drosophila) homolog-associated protein 1",plasma membrane|membrane|cell junction|synapse|synapse|postsynaptic membrane|neuronal postsynaptic density|,cell-cell signaling|synaptic transmission|protein localization to synapse|regulation of proteasomal protein catabolic process|aggresome assembly|,protein domain specific binding|protein complex binding|,10,0.4,3.92,10,0.4,0.824,0.4,4.52,4.52,0.0445,0,0,-0.2,1.2
ENSMUSG00000047667,OLFR26,olfactory receptor 26,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,4.53,10,-0.2,0.724,-0.4,4.47,-4.47,0.0456,0,0,-1.2,0.2
ENSMUSG00000037101,TTC29,tetratricopeptide repeat domain 29,cellular_component|,biological_process|,molecular_function|,9,-0.7,6.93,9,0.1,0.0206,-0.7,4.43,-4.43,0.0464,0,0,-1.8,0.1
ENSMUSG00000034324,TMEM132C,transmembrane protein 132C,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.8,1.89,10,0.4,3.14,0.5,4.42,4.42,0.0466,0,0,-0.2,1.6
ENSMUSG00000072572,SLC39A2,"solute carrier family 39 (zinc transporter), member 2",plasma membrane|cytoplasmic membrane-bounded vesicle|,zinc ion transport|zinc ion transmembrane transport|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|zinc ion transmembrane transporter activity|,10,0.5,4.91,10,0,0,0.5,4.42,4.42,0.0466,0,0,-0.1,1.5
ENSMUSG00000044014,NPY5R,neuropeptide Y receptor Y5,cytoplasm|plasma membrane|membrane|integral component of membrane|neuron projection|,"positive regulation of acute inflammatory response|outflow tract morphogenesis|cardiac left ventricle morphogenesis|signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|synaptic transmission|negative regulation of glutamate secretion|negative regulation of synaptic transmission, GABAergic|eating behavior|negative regulation of apoptotic process|positive regulation of smooth muscle cell proliferation|generation of ovulation cycle rhythm|",peptide YY receptor activity|peptide YY receptor activity|pancreatic polypeptide receptor activity|pancreatic polypeptide receptor activity|signal transducer activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|neuropeptide Y receptor activity|,10,0.4,2.94,10,0.2,1.79,0.3,4.36,4.36,0.048,0,0,-0.3,1.1
ENSMUSG00000079173,ZAN,zonadhesin,plasma membrane|membrane|integral component of membrane|,cell adhesion|binding of sperm to zona pellucida|regulation of binding of sperm to zona pellucida|,extracellular matrix binding|,9,0.4,1.11,9,-1.2,4.6,0.6,4.33,4.33,0.0486,0,0,-1.7,1.7
ENSMUSG00000073932,OLFR641,olfactory receptor 641,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,4.1,10,-0.2,0.657,-0.3,4.33,-4.33,0.0486,0,0,-1.4,0.1
ENSMUSG00000021337,SCGN,"secretagogin, EF-hand calcium binding protein",extracellular region|cytoplasm|membrane|cytoplasmic vesicle|,None,calcium ion binding|metal ion binding|,10,1,2.31,10,0.6,3.51,0.8,4.29,4.29,0.0496,0,0,-0.1,2
ENSMUSG00000050134,OLFR430,olfactory receptor 430,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0282,10,0.9,7.21,0.9,4.28,4.28,0.0497,0,0,-0.6,1.9
ENSMUSG00000021680,CRHBP,corticotropin releasing hormone binding protein,extracellular region|extracellular space|extracellular space|intracellular|nucleus|secondary lysosome|multivesicular body|microtubule|secretory granule|dendrite|dense core granule|varicosity|perikaryon|axon terminus|,"synaptic transmission, dopaminergic|maternal aggressive behavior|inflammatory response|female pregnancy|hormone-mediated signaling pathway|cellular response to stress|cellular response to drug|cellular response to potassium ion|hormone metabolic process|regulated secretory pathway|behavioral response to ethanol|regulation of corticotropin secretion|negative regulation of corticotropin secretion|cellular response to calcium ion|cellular response to cocaine|cellular response to cAMP|cellular response to tumor necrosis factor|cellular response to estrogen stimulus|cellular response to estradiol stimulus|cellular response to estradiol stimulus|cellular response to gonadotropin-releasing hormone|negative regulation of corticotropin-releasing hormone receptor activity|regulation of N-methyl-D-aspartate selective glutamate receptor activity|",peptide binding|corticotropin-releasing hormone binding|corticotropin-releasing hormone binding|corticotropin-releasing hormone binding|,10,-0.7,5.21,10,0.5,1.02,-0.4,4.28,-4.28,0.0497,0,0,-1.7,0.5
ENSMUSG00000024064,GALNT14,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-1.5,7.63,10,0,0,-1.5,4.27,-4.27,0.0499,0,0,-3,-0.1
ENSMUSG00000026301,IQCA,IQ motif containing with AAA domain,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,1.1,3.29,10,0.7,2.13,0.9,4.27,4.27,0.0499,0,0,-0.2,2
ENSMUSG00000019945,1700040L02RIK,RIKEN cDNA 1700040L02 gene,cellular_component|,biological_process|,molecular_function|,10,-0.5,6.25,10,0.2,0.413,-0.5,4.27,-4.27,0.0499,0,0,-1.5,0.8
ENSMUSG00000016262,SERTAD4,SERTA domain containing 4,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0424,10,0.8,6.22,0.6,4.24,4.24,0.0506,0,0,-0.1,1.8
ENSMUSG00000054162,SPOCK3,"sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|,signal transduction|negative regulation of peptidase activity|negative regulation of endopeptidase activity|peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|,enzyme inhibitor activity|calcium ion binding|glycosaminoglycan binding|metalloendopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.8,4.62,10,-0.6,5.99,0.7,4.22,4.22,0.051,0,0,-1.4,1.6
ENSMUSG00000035383,PMCH,pro-melanin-concentrating hormone,extracellular region|extracellular space|nucleus|,"regulation of heart rate|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|synaptic transmission|feeding behavior|feeding behavior|response to cold|negative regulation of synaptic transmission, dopaminergic|glucose homeostasis|drinking behavior|negative regulation of blood pressure|positive regulation of circadian sleep/wake cycle, REM sleep|regulation of neuronal synaptic plasticity|",receptor binding|hormone activity|melanin-concentrating hormone activity|type 1 melanin-concentrating hormone receptor binding|,10,0.6,4.57,10,-0.3,0.661,0.4,4.19,4.19,0.0517,0,0,-0.8,1.5
ENSMUSG00000074028,SLC22A13,"solute carrier family 22 (organic cation transporter), member 13",membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,transport|urate transport|transmembrane transport|nicotinate transport|,transporter activity|transmembrane transporter activity|nicotinate transporter activity|,10,1,2.66,10,0.9,1.88,0.9,4.19,4.19,0.0517,0,0,-0.1,2
ENSMUSG00000062432,CYP26C1,"cytochrome P450, family 26, subfamily c, polypeptide 1",None,central nervous system development|anterior/posterior pattern specification|neural crest cell development|retinoic acid catabolic process|organelle fusion|oxidation-reduction process|,retinoic acid binding|monooxygenase activity|retinoic acid 4-hydroxylase activity|oxidoreductase activity|metal ion binding|,10,0.3,2.62,10,0.5,1.88,0.3,4.19,4.19,0.0517,0,0,-0.3,1.4
ENSMUSG00000048939,ATP13A5,ATPase type 13A5,membrane|integral component of membrane|,cation transport|,nucleotide binding|ATP binding|hydrolase activity|ATPase activity|cation-transporting ATPase activity|metal ion binding|,10,0.3,4.57,10,-0.1,0.121,0.3,4.18,4.18,0.052,0,0,-0.4,1.2
ENSMUSG00000044286,OLFR221,olfactory receptor 221,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-1,7.21,-1,4.17,-4.17,0.0521,0,0,-2,0.7
ENSMUSG00000042909,OLFR648,olfactory receptor 648,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.8,4.7,10,0.3,1.44,0.6,4.15,4.15,0.0525,0,0,-0.2,1.7
ENSMUSG00000075198,OLFR1045,olfactory receptor 1045,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.6,6.57,-0.5,4.14,-4.14,0.0528,0,0,-1.5,0.3
ENSMUSG00000066197,GPR139,G protein-coupled receptor 139,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|,signal transducer activity|G-protein coupled receptor activity|neuropeptide receptor activity|protein dimerization activity|,10,-0.3,4.08,10,-0.2,0.268,-0.3,4.12,-4.12,0.0533,0,0,-1.2,0.3
ENSMUSG00000066382,IQCF5,IQ motif containing F5,cellular_component|,biological_process|,molecular_function|,10,-0.7,5.47,10,-0.1,0.0794,-0.6,4.12,-4.12,0.0533,0,0,-1.6,1.5
ENSMUSG00000046275,TUSC5,tumor suppressor candidate 5,cellular_component|membrane|integral component of membrane|,biological_process|response to biotic stimulus|,molecular_function|,10,-0.3,2.09,10,-0.6,3.04,-0.4,4.11,-4.11,0.0535,0,0,-1.4,0.2
ENSMUSG00000020690,EFCAB3,EF-hand calcium binding domain 3,cellular_component|,biological_process|,molecular_function|calcium ion binding|metal ion binding|,10,-0.2,1.44,10,0.8,5.7,0.7,4.1,4.1,0.0538,0,0,-0.6,1.8
ENSMUSG00000049690,NCKAP5,NCK-associated protein 5,cellular_component|,biological_process|,molecular_function|,10,-0.9,6.01,10,0.7,2.02,-0.8,4.09,-4.09,0.0541,0,0,-2,0.8
ENSMUSG00000035164,ZC3H12C,zinc finger CCCH type containing 12C,cellular_component|,biological_process|,molecular_function|nuclease activity|endonuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,0.4,5.72,10,0,0,0.4,4.04,4.04,0.0553,0,0,-0.3,1.3
ENSMUSG00000020062,SLC5A8,"solute carrier family 5 (iodide transporter), member 8",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|apoptotic process|transmembrane transport|,transporter activity|symporter activity|,10,-1.1,0.236,10,0.4,4.95,0.4,4.03,4.03,0.0555,0,0,-1,1.6
ENSMUSG00000056481,CD248,"CD248 antigen, endosialin",cytoplasm|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,positive regulation of cell proliferation|cell migration|lymph node development|anatomical structure regression|positive regulation of endothelial cell apoptotic process|,calcium ion binding|carbohydrate binding|extracellular matrix binding|,9,0,0,9,0.8,4.52,0.7,4.03,4.03,0.0555,0,0,0,1.9
ENSMUSG00000070577,GM572,predicted gene 572,cellular_component|,biological_process|,molecular_function|,10,-0.7,4.96,10,-0.2,0.627,-0.4,3.99,-3.99,0.0567,0,0,-1.8,0.5
ENSMUSG00000070873,LILRA5,"leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5",extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,2.91,10,0.6,2.37,0.4,3.96,3.96,0.0575,0,0,-0.8,1.5
ENSMUSG00000048031,FCRL5,Fc receptor-like 5,plasma membrane|membrane|integral component of membrane|receptor complex|,negative regulation of B cell receptor signaling pathway|negative regulation of B cell receptor signaling pathway|negative regulation of release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion into cytosol|,protein binding|,10,-0.5,3.43,10,-0.3,1.06,-0.4,3.94,-3.94,0.058,0,0,-1.4,0.3
ENSMUSG00000068816,OLFR152,olfactory receptor 152,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,2.36,10,-0.9,4.4,-0.5,3.93,-3.93,0.0584,0,0,-1.9,0.6
ENSMUSG00000069085,DYTN,dystrotelin,cellular_component|plasma membrane|membrane|,biological_process|,molecular_function|calcium ion binding|zinc ion binding|metal ion binding|,10,1,6.94,10,-0.1,0.298,0.9,3.92,3.92,0.0587,0,0,0.1,2
ENSMUSG00000058400,QRFPR,pyroglutamylated RFamide peptide receptor,plasma membrane|membrane|integral component of membrane|nonmotile primary cilium|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|,10,0.5,2.73,10,0.4,1.59,0.4,3.91,3.91,0.0588,0,0,-0.2,1.5
ENSMUSG00000040866,RSPH6A,radial spoke head 6 homolog A (Chlamydomonas),intracellular|cilium|,biological_process|,molecular_function|,10,-0.7,4.64,10,0,0,-0.7,3.91,-3.91,0.0588,0,0,-1.7,0.1
ENSMUSG00000032344,MB21D1,Mab-21 domain containing 1,cytoplasm|cytosol|cytosol|,activation of innate immune response|activation of innate immune response|positive regulation of defense response to virus by host|positive regulation of defense response to virus by host|immune system process|cyclic nucleotide biosynthetic process|cyclic nucleotide biosynthetic process|innate immune response|defense response to virus|cellular response to exogenous dsRNA|cellular response to exogenous dsRNA|,nucleotide binding|DNA binding|ATP binding|GTP binding|transferase activity|nucleotidyltransferase activity|metal ion binding|cyclic-GMP-AMP synthase activity|cyclic-GMP-AMP synthase activity|,10,-0.6,5,10,0,0,-0.5,3.9,-3.9,0.0591,0,0,-1.6,0.2
ENSMUSG00000024734,ZP1,zona pellucida glycoprotein 1,extracellular region|proteinaceous extracellular matrix|Golgi apparatus|plasma membrane|membrane|integral component of membrane|secretory granule|extracellular matrix|,single fertilization|,None,10,-0.8,6.53,10,0.1,0.0281,-0.7,3.89,-3.89,0.0594,0,0,-1.8,0.1
ENSMUSG00000032921,ODF4,outer dense fiber of sperm tails 4,outer dense fiber|membrane|integral component of membrane|motile cilium|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,0.2,0.713,10,-0.9,6.57,-0.8,3.89,-3.89,0.0594,0,0,-1.9,0.2
ENSMUSG00000040624,PLEKHG1,"pleckstrin homology domain containing, family G (with RhoGef domain) member 1",cellular_component|,biological_process|,molecular_function|,10,-0.3,3.25,10,-0.2,1.01,-0.3,3.89,-3.89,0.0594,0,0,-1.3,0.4
ENSMUSG00000062252,LHFPL5,lipoma HMGIC fusion partner-like 5,plasma membrane|membrane|integral component of membrane|apical plasma membrane|stereocilium bundle|stereocilium bundle tip|,transport|ion transport|sensory perception of sound|detection of mechanical stimulus involved in sensory perception of sound|auditory receptor cell stereocilium organization|,protein binding|,10,0.5,2.56,10,0.4,1.67,0.4,3.86,3.86,0.0602,0,0,-0.2,1.6
ENSMUSG00000021579,LRRC14B,leucine rich repeat containing 14B,cellular_component|,biological_process|,molecular_function|,10,0.8,0.524,10,0.7,3.55,0.7,3.85,3.85,0.0605,0,0,-0.1,1.8
ENSMUSG00000031480,THSD1,"thrombospondin, type I, domain 1",cytoplasm|cytoplasm|cell surface|membrane|integral component of membrane|cell periphery|,hematopoietic progenitor cell differentiation|,molecular_function|,10,-0.4,1.93,10,-0.6,2.4,-0.5,3.85,-3.85,0.0605,0,0,-1.5,0.6
ENSMUSG00000045620,ODF3L1,outer dense fiber of sperm tails 3-like 1,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.88,10,-0.3,2.22,-0.3,3.85,-3.85,0.0605,0,0,-1.3,0.6
ENSMUSG00000045341,OLFR167,olfactory receptor 167,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,2.58,10,0.6,1.64,0.4,3.84,3.84,0.0607,0,0,-0.9,1.5
ENSMUSG00000048191,MUC6,"mucin 6, gastric",cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.4,3.73,10,0.1,0.612,0.4,3.84,3.84,0.0607,0,0,-0.2,1.3
ENSMUSG00000071656,LRRN4CL,LRRN4 C-terminal like,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,1.78,10,-0.8,2.61,0.3,3.8,3.8,0.062,0,0,-1.7,0.9
ENSMUSG00000029182,1700001C02RIK,RIKEN cDNA 1700001C02 gene,nucleus|,biological_process|,molecular_function|,10,-0.6,3.62,10,-0.3,0.764,-0.4,3.79,-3.79,0.0624,0,0,-1.5,0.8
ENSMUSG00000031250,TNMD,tenomodulin,nucleus|membrane|integral component of membrane|,endothelial cell morphogenesis|negative regulation of endothelial cell proliferation|negative regulation of angiogenesis|,None,10,0.3,1.99,10,1,2.99,0.4,3.77,3.77,0.063,0,0,-0.2,1.8
ENSMUSG00000040919,4930505A04RIK,RIKEN cDNA 4930505A04 gene,cellular_component|,biological_process|,molecular_function|,10,0.4,4.79,9,0,0,0.4,3.76,3.76,0.0633,0,0,-0.5,1.4
ENSMUSG00000074736,SYNDIG1,synapse differentiation inducing 1,endosome|plasma membrane|integral component of plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|early endosome membrane|cell projection|dendritic spine|dendritic shaft|cell body|synapse|postsynaptic membrane|excitatory synapse|,intracellular protein transport|response to biotic stimulus|positive regulation of synapse assembly|positive regulation of synapse assembly|synaptic vesicle clustering|,glutamate receptor binding|protein homodimerization activity|,10,0.9,6.69,10,-0.2,0.17,0.9,3.75,3.75,0.0636,0,0,-0.1,2
ENSMUSG00000046805,MPEG1,macrophage expressed gene 1,membrane|integral component of membrane|,None,None,10,0.1,0.241,10,1,6.48,1,3.73,3.73,0.0642,0,0,0.1,2
ENSMUSG00000047441,ANTXRL,anthrax toxin receptor-like,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|receptor activity|metal ion binding|,10,-0.3,2.04,10,-0.9,2.44,-0.3,3.72,-3.72,0.0644,0,0,-1.7,0.1
ENSMUSG00000021306,GPR137B,G protein-coupled receptor 137B,cellular_component|,biological_process|,molecular_function|,10,1.2,3.55,10,0.6,2.04,1.1,3.71,3.71,0.0647,0,0,-0.8,2
ENSMUSG00000006575,RUNDC3A,RUN domain containing 3A,cytosol|plasma membrane|,positive regulation of cGMP biosynthetic process|positive regulation of guanylate cyclase activity|,guanylate cyclase activator activity|peptide hormone receptor binding|,10,1,2.19,10,-0.3,3.11,-0.3,3.68,-3.68,0.0656,0,0,-0.9,1.8
ENSMUSG00000050865,OLFR1494,olfactory receptor 1494,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,3.57,10,0.7,0.882,-0.4,3.66,-3.66,0.0664,0,0,-1.4,1.1
ENSMUSG00000041817,FAM169A,"family with sequence similarity 169, member A",cellular_component|nucleus|membrane|,biological_process|,molecular_function|,10,-0.1,0.349,10,0.4,6.13,0.4,3.65,3.65,0.0666,0,0,-0.4,1.4
ENSMUSG00000039315,CLNK,cytokine-dependent hematopoietic cell linker,intracellular|,transmembrane receptor protein tyrosine kinase signaling pathway|intracellular signal transduction|,protein binding|,10,0.5,3.04,10,1,1.91,0.6,3.64,3.64,0.0671,0,0,-0.4,2
ENSMUSG00000027463,SLC52A3,"solute carrier protein family 52, member 3",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|sensory perception of sound|riboflavin transport|cellular response to heat|,protein binding|riboflavin transporter activity|,10,0.2,1.16,10,0.5,3.03,0.3,3.63,3.63,0.0674,0,0,-0.3,1.4
ENSMUSG00000067526,OLFR1425,olfactory receptor 1425,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,3.56,10,0.8,3.34,0.5,3.6,3.6,0.0684,0,0,-1.7,1.5
ENSMUSG00000047040,PRR15L,proline rich 15-like,cellular_component|,biological_process|,molecular_function|,10,-0.7,4.6,10,1.2,2.5,-0.5,3.58,-3.58,0.0691,0,0,-2,1.4
ENSMUSG00000029660,TEX26,testis expressed 26,cellular_component|,biological_process|,molecular_function|,9,-0.7,3.25,10,0.8,5.78,0.5,3.55,3.55,0.0701,0,0,-1.2,1.8
ENSMUSG00000030385,2900092C05RIK,RIKEN cDNA 2900092C05 gene,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.3,2.95,10,-0.3,0.799,-0.3,3.54,-3.54,0.0703,0,0,-1.4,1.1
ENSMUSG00000046942,MAGEB16,"melanoma antigen family B, 16",cellular_component|,biological_process|,molecular_function|,10,-0.3,1.33,10,-0.7,2.82,-0.6,3.54,-3.54,0.0703,0,0,-1.7,0.1
ENSMUSG00000047910,PCDHB16,protocadherin beta 16,plasma membrane|membrane|integral component of membrane|,cell adhesion|synaptic transmission|synapse assembly|calcium-dependent cell-cell adhesion|,None,10,1.2,5.53,10,-0.4,3.33,-0.3,3.53,-3.53,0.0707,0,0,-0.8,2
ENSMUSG00000046110,SERINC4,serine incorporator 4,None,None,None,10,0.2,0.542,10,-0.6,4.36,-0.5,3.5,-3.5,0.0718,0,0,-1.4,1.1
ENSMUSG00000038192,CER1,cerberus 1 homolog (Xenopus laevis),extracellular region|extracellular region|extracellular space|,ureteric bud development|gastrulation|nervous system development|negative regulation of cell proliferation|anterior/posterior axis specification|anterior/posterior axis specification|anterior/posterior pattern specification|signal transduction involved in regulation of gene expression|bone mineralization|negative regulation of BMP signaling pathway|negative regulation of activin receptor signaling pathway|negative regulation of activin receptor signaling pathway|sequestering of BMP in extracellular matrix|sequestering of BMP in extracellular matrix|cell migration involved in gastrulation|determination of dorsal identity|cellular response to BMP stimulus|negative regulation of mesoderm development|negative regulation of mesoderm development|,cytokine activity|morphogen activity|BMP binding|protein homodimerization activity|,10,-0.2,1.44,10,-0.3,2.31,-0.3,3.46,-3.46,0.0734,0,0,-1.4,0.3
ENSMUSG00000070337,GPR179,G protein-coupled receptor 179,membrane|integral component of membrane|dendrite terminus|,signal transduction|G-protein coupled receptor signaling pathway|visual perception|protein localization to plasma membrane|,signal transducer activity|G-protein coupled receptor activity|protein binding|,10,0.6,2.08,10,0.7,1.62,0.6,3.46,3.46,0.0734,0,0,-0.3,1.7
ENSMUSG00000096254,OLFR724,olfactory receptor 724,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.397,9,-0.6,3.49,-0.6,3.45,-3.45,0.0737,0,0,-1.7,1.2
ENSMUSG00000079022,COL22A1,"collagen, type XXII, alpha 1",cellular_component|,biological_process|,molecular_function|,10,-0.5,1.72,10,0.4,2.38,-0.6,3.42,-3.42,0.0751,0,0,-1.7,1
ENSMUSG00000056853,OLFR765,olfactory receptor 765,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.229,10,0.7,5.23,0.6,3.41,3.41,0.0754,0,0,-0.2,1.8
ENSMUSG00000030775,TRAT1,T cell receptor associated transmembrane adaptor 1,plasma membrane|membrane|integral component of membrane|T cell receptor complex|,negative regulation of receptor recycling|immune system process|positive regulation of calcium-mediated signaling|positive regulation of T cell receptor signaling pathway|negative regulation of transport|,molecular_function|,9,-0.3,1.03,9,-0.4,2.58,-0.4,3.37,-3.37,0.0768,0,0,-1.5,0.5
ENSMUSG00000026065,SLC9A4,"solute carrier family 9 (sodium/hydrogen exchanger), member 4",plasma membrane|membrane|integral component of membrane|,gastric acid secretion|epithelial cell development|transport|ion transport|cation transport|sodium ion transport|regulation of pH|transmembrane transport|,antiporter activity|solute:proton antiporter activity|sodium:proton antiporter activity|,10,-0.9,6.01,10,0,0,-0.7,3.35,-3.35,0.0776,0,0,-1.9,0.4
ENSMUSG00000067206,LRRC66,leucine rich repeat containing 66,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,2.3,10,0.4,1.53,0.5,3.34,3.34,0.078,0,0,-0.8,1.6
ENSMUSG00000052562,SLC22A30,"solute carrier family 22, member 30",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.7,4.69,10,0.2,0.346,0.5,3.34,3.34,0.078,0,0,-0.1,1.7
ENSMUSG00000026931,1700019N19RIK,RIKEN cDNA 1700019N19 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,1.4,10,0.4,2.19,0.3,3.33,3.33,0.0784,0,0,-0.8,1.4
ENSMUSG00000028139,RIIAD1,regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.5,5.45,10,0.1,0.0285,-0.4,3.33,-3.33,0.0784,0,0,-1.5,1
ENSMUSG00000058030,VMN1R237,vomeronasal 1 receptor 237,integral component of plasma membrane|,G-protein coupled receptor signaling pathway|response to pheromone|,pheromone binding|pheromone receptor activity|,10,-0.3,3.59,10,0,0,-0.3,3.33,-3.33,0.0784,0,0,-1.4,1
ENSMUSG00000021638,OCLN,occludin,cytosol|plasma membrane|plasma membrane|cell-cell junction|cell-cell junction|tight junction|tight junction|cell surface|membrane|integral component of membrane|apical plasma membrane|apicolateral plasma membrane|cell junction|endocytic vesicle|cytoplasmic vesicle|,methylation|cell-cell junction organization|S-adenosylhomocysteine metabolic process|S-adenosylmethionine metabolic process|tight junction assembly|,structural molecule activity|protein binding|thiopurine S-methyltransferase activity|S-adenosylmethionine-dependent methyltransferase activity|protein domain specific binding|,10,0.7,1.45,10,0.3,2.5,0.3,3.31,3.31,0.0793,0,0,-0.3,1.6
ENSMUSG00000015944,GATSL2,GATS protein-like 2,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.8,10,-0.2,1.05,-0.3,3.31,-3.31,0.0793,0,0,-1.5,1.2
ENSMUSG00000030549,RHCG,Rhesus blood group-associated C glycoprotein,plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|apical plasma membrane|cytoplasmic vesicle|extracellular vesicular exosome|,transport|cellular ion homeostasis|regulation of pH|organic cation transport|ammonium transport|ammonium transport|transepithelial ammonium transport|ammonium transmembrane transport|ammonium transmembrane transport|,ammonium transmembrane transporter activity|ammonium transmembrane transporter activity|ankyrin binding|,10,0.2,0.429,10,0.4,3.65,0.3,3.29,3.29,0.0802,0,0,-0.3,1.4
ENSMUSG00000021675,F2RL2,coagulation factor II (thrombin) receptor-like 2,plasma membrane|membrane|integral component of membrane|apical plasma membrane|,signal transduction|G-protein coupled receptor signaling pathway|blood coagulation|hemostasis|thrombin receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|thrombin receptor activity|,10,0.3,0.915,10,0.7,3.03,0.3,3.28,3.28,0.0806,0,0,-0.2,1.7
ENSMUSG00000067064,OLFR1416,olfactory receptor 1416,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,4.34,10,0.3,3.51,-0.3,3.28,-3.28,0.0806,0,0,-1.5,0.9
ENSMUSG00000044556,TEX38,testis expressed 38,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,2.49,10,-1.3,1.95,-1.2,3.27,-3.27,0.081,0,0,-2,0.4
ENSMUSG00000070044,FAM149A,"family with sequence similarity 149, member A",cellular_component|,biological_process|,molecular_function|,10,1.2,3.04,10,-0.3,0.671,-0.4,3.24,-3.24,0.0822,0,0,-1.2,1.8
ENSMUSG00000033377,PALMD,palmdelphin,cytoplasm|cytoplasm|cytoplasm|membrane|dendrite|cell projection|dendritic spine|,regulation of cell shape|,protein binding|,10,0.9,2.04,10,1,1.45,1,3.22,3.22,0.0831,0,0,-0.1,2
ENSMUSG00000066705,FXYD6,FXYD domain-containing ion transport regulator 6,plasma membrane|membrane|integral component of membrane|,transport|ion transport|,ion channel activity|,10,-1.5,6.64,10,0,0,-1.5,3.22,-3.22,0.0831,0,0,-3,1.3
ENSMUSG00000031399,FAM3A,"family with sequence similarity 3, member A",cellular_component|extracellular region|,biological_process|,molecular_function|,10,-1.1,4.38,10,-0.3,0.687,-0.8,3.22,-3.22,0.0831,0,0,-2,0.1
ENSMUSG00000057766,ANKRD29,ankyrin repeat domain 29,cellular_component|,biological_process|,molecular_function|,10,0.3,0.843,10,0.6,2.97,0.3,3.21,3.21,0.0835,0,0,-0.4,1.6
ENSMUSG00000027977,NDST3,N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3,Golgi apparatus|membrane|integral component of membrane|,metabolic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|catalytic activity|GPI-anchor transamidase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|[heparan sulfate]-glucosamine N-sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|hydrolase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|deacetylase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|hydroxyjasmonate sulfotransferase activity|",10,-0.3,1.4,10,-0.5,2.2,-0.4,3.2,-3.2,0.0839,0,0,-1.5,0.8
ENSMUSG00000093884,OLFR239,olfactory receptor 239,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,1,2.82,10,0.5,1.46,0.7,3.19,3.19,0.0844,0,0,-0.1,1.9
ENSMUSG00000053886,SH2D4A,SH2 domain containing 4A,cytoplasm|cytoplasm|,negative regulation of phosphatase activity|,phosphatase binding|,10,-0.5,1.68,10,-0.4,1.88,-0.5,3.19,-3.19,0.0844,0,0,-1.6,0.7
ENSMUSG00000043366,OLFR78,olfactory receptor 78,plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|sensory perception of smell|steroid hormone mediated signaling pathway|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,steroid hormone receptor activity|signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|olfactory receptor activity|olfactory receptor activity|,10,0.3,1.8,10,-0.9,6.07,-0.9,3.18,-3.18,0.0848,0,0,-2,0.6
ENSMUSG00000047786,LIX1,limb expression 1 homolog (chicken),cellular_component|,biological_process|,molecular_function|,10,0.3,4.33,10,0,0,0.3,3.15,3.15,0.0862,0,0,-0.9,1.5
ENSMUSG00000043036,CCDC63,coiled-coil domain containing 63,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.859,10,-0.8,3.54,-0.6,3.15,-3.15,0.0862,0,0,-1.8,0.3
ENSMUSG00000042262,CCR8,chemokine (C-C motif) receptor 8,plasma membrane|membrane|integral component of membrane|,chemotaxis|immune response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|,10,-0.3,2.9,10,-0.2,0.484,-0.3,3.14,-3.14,0.0867,0,0,-1.4,0.7
ENSMUSG00000090874,OLFR733,olfactory receptor 733,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,1.16,10,0.6,2.82,0.3,3.13,3.13,0.0871,0,0,-0.4,1.6
ENSMUSG00000045514,OLFR460,olfactory receptor 460,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,1.22,10,0.3,3.27,0.3,3.13,3.13,0.0871,0,0,-1.2,1.2
ENSMUSG00000069372,CTXN3,cortexin 3,cellular_component|membrane|integral component of membrane|intrinsic component of membrane|,biological_process|,molecular_function|,10,0.1,0.0424,10,-0.5,4.54,-0.4,3.12,-3.12,0.0875,0,0,-1.6,0.4
ENSMUSG00000051431,GPR87,G protein-coupled receptor 87,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled purinergic nucleotide receptor activity|,10,0.5,3.56,10,0.2,0.557,0.4,3.11,3.11,0.088,0,0,-0.5,1.7
ENSMUSG00000026327,SERPINB11,"serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11",extracellular space|cytoplasm|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.2,0.58,10,-0.6,3.08,-0.6,3.1,-3.1,0.0884,0,0,-1.7,0.8
ENSMUSG00000074417,GM14548,predicted gene 14548,cellular_component|,biological_process|,molecular_function|,10,-0.4,4.47,10,0.1,0.022,-0.3,3.1,-3.1,0.0884,0,0,-1.5,0.7
ENSMUSG00000026158,OGFRL1,opioid growth factor receptor-like 1,cellular_component|membrane|,biological_process|,molecular_function|receptor activity|,10,0.5,2.82,10,0.5,0.451,0.5,3.09,3.09,0.0887,0,0,-0.6,1.5
ENSMUSG00000060422,OLFR1034,olfactory receptor 1034,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1.1,5.72,10,0.2,0.59,-1,3.08,-3.08,0.0893,0,0,-2,0.2
ENSMUSG00000096204,TAAR8C,trace amine-associated receptor 8C,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,trace-amine receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|,10,-0.4,2.55,10,0.2,1.17,0.4,3.07,3.07,0.0897,0,0,-1,1.3
ENSMUSG00000056155,NANOS3,nanos homolog 3 (Drosophila),cytoplasmic mRNA processing body|nucleus|nucleus|cytoplasm|cytoplasm|cytoplasmic stress granule|perinuclear region of cytoplasm|,regulation of translation|multicellular organismal development|germ cell development|spermatogenesis|spermatogenesis|cell differentiation|oogenesis|regulation of cell cycle|negative regulation of apoptotic signaling pathway|negative regulation of apoptotic signaling pathway|,RNA binding|protein binding|zinc ion binding|metal ion binding|,10,0.4,2.51,10,-0.4,2.12,0.5,3.06,3.06,0.0901,0,0,-1.5,1.4
ENSMUSG00000051079,RGS13,regulator of G-protein signaling 13,nucleus|cytosol|plasma membrane|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|negative regulation of G-protein coupled receptor protein signaling pathway|,GTPase activator activity|protein binding|,10,0,0,10,0.5,5.09,0.3,3.06,3.06,0.0901,0,0,-0.3,1.8
ENSMUSG00000091212,KRTAP11-1,keratin associated protein 11-1,cellular_component|,biological_process|,molecular_function|,10,-0.4,3.77,10,-0.1,0.00654,-0.3,3.05,-3.05,0.0905,0,0,-1.4,1.2
ENSMUSG00000032852,RSPO4,"R-spondin family, member 4",extracellular region|,Wnt signaling pathway|response to stimulus|,heparin binding|,10,-0.4,3.73,10,0.1,0.313,-0.4,3.05,-3.05,0.0905,0,0,-1.6,0.4
ENSMUSG00000050875,A730017C20RIK,RIKEN cDNA A730017C20 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.5,3.85,10,0.2,0.291,0.3,3.05,3.05,0.0905,0,0,-0.4,1.5
ENSMUSG00000019932,KERA,keratocan,extracellular region|proteinaceous extracellular matrix|,cornea development in camera-type eye|,None,10,0.5,1.45,10,-0.4,2.93,-0.3,3.04,-3.04,0.0908,0,0,-1.2,1.2
ENSMUSG00000017720,TRP53TG5,transformation related protein 53 target 5,nucleus|,biological_process|,molecular_function|,10,-0.5,4.82,10,0.8,1.64,-0.3,3.03,-3.03,0.0914,0,0,-1.3,1.5
ENSMUSG00000048284,TAS2R126,"taste receptor, type 2, member 126",membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.4,1.3,10,-0.4,1.93,-0.4,3.02,-3.02,0.0919,0,0,-1.7,0.5
ENSMUSG00000030160,TMEM52B,transmembrane protein 52B,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.2,0.681,10,0.5,3.26,0.3,3.01,3.01,0.0923,0,0,-1.1,1.5
ENSMUSG00000071719,TMEM28,transmembrane protein 28,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,2.4,10,-0.5,1.07,-0.3,3.01,-3.01,0.0923,0,0,-1.5,0.8
ENSMUSG00000095721,GM7137,predicted gene 7137,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.6,4.99,10,-1.2,1.21,0.4,3.01,3.01,0.0923,0,0,-1.3,1.8
ENSMUSG00000062142,OLFR569,olfactory receptor 569,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.3,10,-0.6,4.6,-0.5,3.01,-3.01,0.0923,0,0,-1.6,0.7
ENSMUSG00000057715,A830018L16RIK,RIKEN cDNA A830018L16 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.199,10,0.8,5.65,0.5,3.01,3.01,0.0923,0,0,-0.1,1.9
ENSMUSG00000056972,MAGEL2,"melanoma antigen, family L, 2",endosome|retromer complex|,"Arp2/3 complex-mediated actin nucleation|retrograde transport, endosome to Golgi|protein K63-linked ubiquitination|",ubiquitin-protein transferase activity|protein binding|,10,-0.8,5.41,10,0.3,1.06,-0.8,3,-3,0.0928,0,0,-1.9,0.3
ENSMUSG00000071522,OLFR263,olfactory receptor 263,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|,10,-1,4.37,10,0.2,0.605,-0.7,2.99,-2.99,0.0934,0,0,-1.9,0.4
ENSMUSG00000049908,GJA8,"gap junction protein, alpha 8",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,lens development in camera-type eye|cell communication|cell-cell signaling|camera-type eye development|protein homooligomerization|transmembrane transport|,gap junction channel activity|,10,-0.6,2.7,10,0.5,2.44,-0.4,2.97,-2.97,0.0944,0,0,-1.5,1.1
ENSMUSG00000070377,OLFR43,olfactory receptor 43,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.43,10,0.3,1.75,0.3,2.97,2.97,0.0944,0,0,-0.5,1.4
ENSMUSG00000024842,CABP4,calcium binding protein 4,cytoplasm|cytosol|,visual perception|phototransduction|photoreceptor cell morphogenesis|retinal cone cell development|retinal bipolar neuron differentiation|,calcium ion binding|metal ion binding|,10,0.2,0.959,10,0.4,2.26,0.3,2.95,2.95,0.0952,0,0,-0.6,1.5
ENSMUSG00000053863,MEPE,matrix extracellular phosphoglycoprotein with ASARM motif (bone),proteinaceous extracellular matrix|,skeletal system development|negative regulation of bone mineralization|negative regulation of bone mineralization|,molecular_function|,10,-0.2,1.6,10,-1.1,2.63,-0.4,2.94,-2.94,0.0957,0,0,-1.9,0.1
ENSMUSG00000049093,IL23R,interleukin 23 receptor,intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|interleukin-23 receptor complex|,positive regulation of defense response to virus by host|immune system process|leukocyte mediated immunity|positive regulation of T-helper 1 type immune response|inflammatory response|JAK-STAT cascade|cytokine-mediated signaling pathway|response to lipopolysaccharide|negative regulation of interleukin-10 production|positive regulation of interferon-gamma production|positive regulation of interleukin-12 production|response to interferon-gamma|interleukin-23-mediated signaling pathway|innate immune response|,interleukin-12 receptor binding|interleukin-23 binding|interleukin-23 binding|interleukin-23 receptor activity|interleukin-23 receptor activity|,10,0.8,2.83,10,0.6,0.496,0.7,2.94,2.94,0.0957,0,0,-0.3,2
ENSMUSG00000052117,D630039A03RIK,RIKEN cDNA D630039A03 gene,cellular_component|,biological_process|,molecular_function|,10,0.6,5.48,10,-0.6,2.09,0.5,2.93,2.93,0.0961,0,0,-1,1.8
ENSMUSG00000022342,KCNV1,"potassium channel, subfamily V, member 1",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.4,3.76,10,-0.2,0.615,0.3,2.93,2.93,0.0961,0,0,-0.7,1.4
ENSMUSG00000058260,SERPINA9,"serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9",cellular_component|extracellular region|extracellular space|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.3,1.7,10,-0.7,2.84,-0.5,2.92,-2.92,0.0966,0,0,-1.7,0.5
ENSMUSG00000073979,OLFR547,olfactory receptor 547,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|cognition|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,2.34,10,-0.4,0.766,-0.3,2.9,-2.9,0.0975,0,0,-1.4,0.9
ENSMUSG00000073568,ARL14EPL,ADP-ribosylation factor-like 14 effector protein-like,cellular_component|,biological_process|,molecular_function|,10,0.4,3.8,10,0,0,0.4,2.9,2.9,0.0975,0,0,-0.3,1.5
ENSMUSG00000030523,TRPM1,"transient receptor potential cation channel, subfamily M, member 1",intracellular|cell|plasma membrane|membrane|integral component of membrane|new growing cell tip|,transport|ion transport|cation transport|signal transduction|G-protein coupled glutamate receptor signaling pathway|visual perception|ion transmembrane transport|retinal rod cell development|response to stimulus|transmembrane transport|calcium ion transport into cytosol|calcium ion transmembrane transport|cellular response to light stimulus|cellular response to light stimulus|,ion channel activity|cation channel activity|calcium channel activity|,10,1,2.11,10,-0.6,2.1,-0.5,2.88,-2.88,0.0985,0,0,-1.4,1.7
ENSMUSG00000044350,LACC1,laccase (multicopper oxidoreductase) domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-1.6,5.64,10,0,0,-1.5,2.88,-2.88,0.0985,0,0,-3,0.6
ENSMUSG00000047773,ANKFN1,ankyrin-repeat and fibronectin type III domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.6,5.24,10,-0.6,1.52,0.5,2.86,2.86,0.0996,0,0,-1.1,1.7
ENSMUSG00000009580,ODAM,"odontogenic, ameloblast asssociated",extracellular region|nucleus|cytoplasm|fibril|,biological_process|biomineral tissue development|,molecular_function|,10,-0.2,1.17,10,0.4,3.39,0.2,2.85,2.85,0.1,0,0,-0.7,1.7
ENSMUSG00000062285,OLFR1386,olfactory receptor 1386,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,0.736,10,0.8,5.71,0.8,2.85,2.85,0.1,0,0,-0.3,2
ENSMUSG00000029370,RASSF6,Ras association (RalGDS/AF-6) domain family member 6,cellular_component|,apoptotic process|signal transduction|regulation of apoptotic process|positive regulation of apoptotic process|,protein binding|,10,-0.1,0.201,10,0.4,3.52,0.3,2.84,2.84,0.101,0,0,-0.7,1.4
ENSMUSG00000025876,UNC5A,unc-5 homolog A (C. elegans),plasma membrane|membrane|integral component of membrane|,apoptotic process|signal transduction|multicellular organismal development|axon guidance|anterior/posterior axon guidance|netrin-activated signaling pathway|,netrin receptor activity|,10,-0.4,3.86,10,0,0,-0.3,2.83,-2.83,0.101,0,0,-1.6,0.5
ENSMUSG00000095746,SNURF,SNRPN upstream reading frame,nucleus|,None,None,10,-0.4,3.93,10,0.2,0.791,-0.3,2.83,-2.83,0.101,0,0,-1.4,0.7
ENSMUSG00000095788,SIRPB1A,signal-regulatory protein beta 1A,intracellular|plasma membrane|extracellular vesicular exosome|,intracellular signal transduction|positive regulation of phagocytosis|,molecular_function|,10,-0.3,2.09,10,-0.8,1.34,-0.3,2.82,-2.82,0.102,0,0,-1.8,0.6
ENSMUSG00000038045,SULT6B1,"sulfotransferase family, cytosolic, 6B, member 1",cellular_component|cytoplasm|,biological_process|,molecular_function|sulfotransferase activity|transferase activity|,10,-0.3,2.39,10,0.3,1.07,-0.3,2.82,-2.82,0.102,0,0,-1.5,0.9
ENSMUSG00000043931,GIMAP7,"GTPase, IMAP family member 7",lipid particle|,GTP catabolic process|,GTPase activity|GTP binding|protein homodimerization activity|,10,-0.5,2.95,10,-0.2,0.759,-0.4,2.82,-2.82,0.102,0,0,-1.5,1.2
ENSMUSG00000034151,ZBBX,"zinc finger, B-box domain containing",cellular_component|intracellular|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.5,3.22,10,-0.1,0.284,-0.5,2.78,-2.78,0.104,0,0,-1.8,0.1
ENSMUSG00000001672,MARVELD3,MARVEL (membrane-associating) domain containing 3,tight junction|tight junction|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|,cell-cell junction organization|cell-cell junction organization|tight junction assembly|,molecular_function|,10,0.3,2.84,10,0.2,0.218,0.3,2.78,2.78,0.104,0,0,-0.8,1.4
ENSMUSG00000059043,OLFR15,olfactory receptor 15,plasma membrane|cell cortex|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,1.96,10,0.5,2.15,0.3,2.77,2.77,0.104,0,0,-1,1.3
ENSMUSG00000073969,OLFR556,olfactory receptor 556,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,3.05,10,0,0,-0.4,2.73,-2.73,0.106,0,0,-1.5,0.4
ENSMUSG00000026051,1500015O10RIK,RIKEN cDNA 1500015O10 gene,extracellular region|extracellular space|cytoplasmic vesicle|,cyclin catabolic process|G1 to G0 transition|cellular senescence|,molecular_function|,10,0.1,0.102,10,0.4,3.32,0.4,2.73,2.73,0.106,0,0,-1,1.6
ENSMUSG00000047794,OLFR685,olfactory receptor 685,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,0.4,2.7,10,0.9,1.25,0.3,2.72,2.72,0.107,0,0,-0.3,1.8
ENSMUSG00000022723,CRYBG3,beta-gamma crystallin domain containing 3,cellular_component|,biological_process|,molecular_function|,10,0.9,3.23,10,0.2,0.765,0.2,2.72,2.72,0.107,0,0,-0.3,2
ENSMUSG00000020411,NIPAL4,NIPA-like domain containing 4,cellular_component|membrane|integral component of membrane|,transport|ion transport|magnesium ion transport|,molecular_function|magnesium ion transmembrane transporter activity|,9,0.3,1.62,9,0.3,1.28,0.3,2.71,2.71,0.108,0,0,-0.5,1.6
ENSMUSG00000063106,OLFR1510,olfactory receptor 1510,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,0.562,10,-0.6,2.56,-0.5,2.67,-2.67,0.11,0,0,-1.9,0.6
ENSMUSG00000033063,CNTNAP3,contactin associated protein-like 3,cellular_component|,biological_process|,molecular_function|,9,0.5,4.05,9,0,0,0.4,2.66,2.66,0.111,0,0,-0.3,1.8
ENSMUSG00000055114,ANXA13,annexin A13,extracellular space|plasma membrane|membrane|extracellular vesicular exosome|,biological_process|,phosphatidylserine binding|calcium ion binding|calcium-dependent phospholipid binding|phosphatidylglycerol binding|,9,-0.3,3.21,9,-0.1,0.0456,-0.4,2.66,-2.66,0.111,0,0,-1.7,0.6
ENSMUSG00000046431,OLFR518,olfactory receptor 518,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.7,4.93,10,0,0,-0.7,2.66,-2.66,0.111,0,0,-2,0.6
ENSMUSG00000039611,TMEM246,transmembrane protein 246,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,-0.4,1.6,8,-0.3,1.25,-0.3,2.65,-2.65,0.111,0,0,-1.6,0.6
ENSMUSG00000050558,PROKR2,prokineticin receptor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|circadian rhythm|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|,10,-1,1.48,10,-0.7,1.7,-0.8,2.65,-2.65,0.111,0,0,-1.9,0.3
ENSMUSG00000057137,TMEM140,transmembrane protein 140,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.99,10,-0.3,0.842,-0.3,2.65,-2.65,0.111,0,0,-1.7,0.6
ENSMUSG00000006435,NEURL1A,neuralized homolog 1A (Drosophila),cytoplasm|cytoplasm|plasma membrane|plasma membrane|postsynaptic density|membrane|cell junction|cell projection|dendritic spine|perikaryon|synapse|postsynaptic membrane|apical dendrite|,regulation of translation|protein monoubiquitination|Notch signaling pathway|sperm axoneme assembly|lactation|negative regulation of cell proliferation|sperm motility|positive regulation of apoptotic process|positive regulation of epidermal growth factor-activated receptor activity|negative regulation of Notch signaling pathway|positive regulation of long-term neuronal synaptic plasticity|positive regulation of filopodium assembly|positive regulation of dendritic spine development|cellular response to amino acid stimulus|positive regulation of synapse maturation|,"ubiquitin-protein transferase activity|protein binding|zinc ion binding|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|translation factor activity, non-nucleic acid binding|metal ion binding|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,0.9,3.83,10,0.2,0.65,0.5,2.65,2.65,0.111,0,0,-0.4,1.9
ENSMUSG00000029333,RASGEF1B,"RasGEF domain family, member 1B",intracellular|endosome|,small GTPase mediated signal transduction|positive regulation of Ras GTPase activity|regulation of small GTPase mediated signal transduction|,guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity|,10,-0.2,0.528,10,-0.3,2.37,-0.3,2.64,-2.64,0.112,0,0,-1.5,0.4
ENSMUSG00000046041,OLFR803,olfactory receptor 803,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,0.3,1.7,10,0.2,1.22,0.3,2.63,2.63,0.112,0,0,-1.4,1.3
ENSMUSG00000060827,OLFR1193,olfactory receptor 1193,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,3.97,10,-0.8,1.92,0.4,2.62,2.62,0.113,0,0,-1.3,1.7
ENSMUSG00000021907,MSMB,beta-microseminoprotein,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.6,4.42,10,0,0,-0.3,2.61,-2.61,0.114,0,0,-1.7,0.3
ENSMUSG00000014351,GIP,gastric inhibitory polypeptide,extracellular region|extracellular space|cytoplasm|neuronal cell body|,response to acid|memory|adult locomotory behavior|positive regulation of glucose transport|sensory perception of pain|endocrine pancreas development|positive regulation of insulin secretion|exploration behavior|positive regulation of cAMP-mediated signaling|positive regulation of synaptic transmission|long-term synaptic potentiation|positive regulation of glucagon secretion|triglyceride homeostasis|,receptor binding|hormone activity|,9,0.3,1.96,9,0.3,0.762,0.3,2.55,2.55,0.117,0,0,-0.5,1.6
ENSMUSG00000027518,1700021F07RIK,RIKEN cDNA 1700021F07 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.228,10,-0.6,3.99,-0.5,2.55,-2.55,0.117,0,0,-1.7,0.2
ENSMUSG00000028269,GBP2B,guanylate binding protein 2b,extracellular region|cytoplasm|Golgi apparatus|membrane|symbiont-containing vacuole membrane|cytoplasmic vesicle|,immune system process|cellular response to interferon-beta|defense response to protozoan|adhesion of symbiont to host|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|defense response to virus|cellular response to interferon-gamma|,nucleotide binding|GTPase activity|GTP binding|GMP binding|,10,-0.2,0.757,10,-0.3,2.18,-0.3,2.55,-2.55,0.117,0,0,-1.3,0.9
ENSMUSG00000075143,OLFR1157,olfactory receptor 1157,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,2.07,10,0.2,0.961,0.3,2.55,2.55,0.117,0,0,-1,1.6
ENSMUSG00000039198,PTCHD3,patched domain containing 3,membrane|integral component of membrane|sperm midpiece|,None,hedgehog receptor activity|,9,0.4,2.11,9,0.2,1.12,0.3,2.54,2.54,0.118,0,0,-1.2,1.4
ENSMUSG00000030142,CLEC4E,"C-type lectin domain family 4, member e",membrane|integral component of membrane|,immune system process|immune response|positive regulation of cytokine secretion|,receptor activity|protein binding|carbohydrate binding|,10,-0.7,1.36,10,0.3,2.75,0.3,2.54,2.54,0.118,0,0,-1.6,1.1
ENSMUSG00000033960,9430020K01RIK,RIKEN cDNA 9430020K01 gene,cell-cell junction|cell junction|,cell adhesion|biological_process|,molecular_function|,10,-0.5,3.5,10,0.6,3.01,0.6,2.53,2.53,0.119,0,0,-1.1,1.7
ENSMUSG00000092417,GPANK1,G patch domain and ankyrin repeats 1,cellular_component|,biological_process|,nucleic acid binding|protein binding|,10,0,0,10,0.5,2.87,0.5,2.53,2.53,0.119,0,0,-0.4,1.7
ENSMUSG00000031073,FGF15,fibroblast growth factor 15,extracellular region|,neural crest cell migration|heart development|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|positive regulation of glucose import|positive regulation of JNK cascade|positive regulation of ERK1 and ERK2 cascade|negative regulation of bile acid biosynthetic process|negative regulation of bile acid biosynthetic process|,receptor binding|fibroblast growth factor receptor binding|protein binding|growth factor activity|,10,-0.4,2.66,10,-0.1,0.187,-0.4,2.53,-2.53,0.119,0,0,-1.7,0.9
ENSMUSG00000043633,FAM221B,"family with sequence similarity 221, member B",cellular_component|,biological_process|,molecular_function|,10,-0.3,3.21,10,0.1,0.0338,-0.3,2.53,-2.53,0.119,0,0,-1.7,0.6
ENSMUSG00000025272,TRO,trophinin,nucleus|cytoplasm|plasma membrane|,cell adhesion|negative regulation of cell growth|,molecular_function|,10,-1.2,2.12,10,0.3,1.44,0.3,2.52,2.52,0.119,0,0,-1.9,1
ENSMUSG00000079362,GBP6,guanylate binding protein 6,symbiont-containing vacuole membrane|cytoplasmic vesicle|extracellular vesicular exosome|,immune response|cellular response to interferon-beta|defense response to bacterium|defense response to protozoan|adhesion of symbiont to host|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|cellular response to lipopolysaccharide|cellular response to interferon-gamma|,molecular_function|,10,1,1.84,10,-1.1,5.61,-1,2.51,-2.51,0.12,0,0,-2,1.3
ENSMUSG00000094140,OLFR1512,olfactory receptor 1512,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,4.28,10,0.3,1.31,-0.3,2.51,-2.51,0.12,0,0,-1.3,0.9
ENSMUSG00000055632,HMCN2,hemicentin 2,extracellular region|proteinaceous extracellular matrix|basement membrane|cell cortex|cell junction|,biological_process|response to stimulus|,calcium ion binding|,10,-0.2,2.08,10,-0.2,0.585,-0.2,2.49,-2.49,0.121,0,0,-1.4,0.6
ENSMUSG00000051497,KCNJ16,"potassium inwardly-rectifying channel, subfamily J, member 16",plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|cellular potassium ion transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|,10,0.4,2.28,10,0.2,0.47,0.3,2.48,2.48,0.122,0,0,-0.7,1.7
ENSMUSG00000071636,RIMBP3,RIMS binding protein 3,nucleus|,None,None,10,0.8,0.943,10,0.6,1.95,0.6,2.47,2.47,0.123,0,0,-0.5,1.9
ENSMUSG00000026424,GPR37L1,G protein-coupled receptor 37-like 1,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cerebellar granule cell precursor proliferation|negative regulation of neuron differentiation|negative regulation of smoothened signaling pathway|negative regulation of astrocyte differentiation|,signal transducer activity|G-protein coupled receptor activity|protein binding|,10,1,3.02,10,0.3,1.54,0.3,2.47,2.47,0.123,0,0,-0.9,2
ENSMUSG00000023336,WFDC1,WAP four-disulfide core domain 1,extracellular region|extracellular space|,regulation of cell growth|negative regulation of peptidase activity|negative regulation of epithelial cell proliferation|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.5,1.63,10,-0.3,1.27,-0.3,2.47,-2.47,0.123,0,0,-1.7,0.5
ENSMUSG00000036907,C1QL2,"complement component 1, q subcomponent-like 2",extracellular region|collagen trimer|,protein oligomerization|,protein binding|identical protein binding|,10,0.3,1.82,10,-0.8,1.08,0.2,2.46,2.46,0.123,0,0,-1.6,1.1
ENSMUSG00000034031,1700106J16RIK,RIKEN cDNA 1700106J16 gene,cellular_component|,biological_process|,molecular_function|,10,-0.4,2.71,10,0,0,-0.4,2.44,-2.44,0.125,0,0,-1.7,0.3
ENSMUSG00000095593,GM7138,predicted gene 7138,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.3,0.399,10,-1.1,3.85,-0.8,2.43,-2.43,0.125,0,0,-2,1
ENSMUSG00000071195,GM10318,predicted gene 10318,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.1,0.48,10,0.6,3.02,0.4,2.42,2.42,0.126,0,0,-1.2,1.5
ENSMUSG00000029607,ANKRD61,ankyrin repeat domain 61,cellular_component|,biological_process|,molecular_function|DNA binding|,10,-0.5,1.79,10,-0.4,0.845,-0.5,2.42,-2.42,0.126,0,0,-1.7,0.5
ENSMUSG00000031119,GPC4,glypican 4,extracellular region|proteinaceous extracellular matrix|nucleus|plasma membrane|external side of plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,None,heparan sulfate proteoglycan binding|,10,0.4,2.91,10,0.1,0.631,0.3,2.41,2.41,0.127,0,0,-0.9,1.6
ENSMUSG00000016498,PDCD1LG2,programmed cell death 1 ligand 2,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,positive regulation of T cell proliferation|negative regulation of T cell proliferation|,protein binding|,10,0.5,4.35,10,0,0,0.4,2.41,2.41,0.127,0,0,-0.6,1.7
ENSMUSG00000038148,CLDN16,claudin 16,plasma membrane|tight junction|tight junction|membrane|integral component of membrane|cell junction|,transport|ion transport|positive regulation of calcium ion transport|transepithelial transport|,structural molecule activity|,10,-0.9,1.17,10,-1.1,1.7,-1,2.41,-2.41,0.127,0,0,-2,0.3
ENSMUSG00000046321,HS3ST2,heparan sulfate (glucosamine) 3-O-sulfotransferase 2,cellular_component|Golgi apparatus|membrane|integral component of membrane|,circadian rhythm|,molecular_function|sulfotransferase activity|transferase activity|[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity|,10,0,0,10,0.7,4.18,0.4,2.39,2.39,0.129,0,0,-0.5,1.8
ENSMUSG00000054526,OLFR1500,olfactory receptor 1500,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,3.19,10,-0.1,0.225,0.3,2.39,2.39,0.129,0,0,-0.7,1.5
ENSMUSG00000026989,DAPL1,death associated protein-like 1,cellular_component|,apoptotic process|biological_process|cell differentiation|,molecular_function|,10,0.3,2.29,10,0.1,0.466,0.2,2.39,2.39,0.129,0,0,-0.4,1.7
ENSMUSG00000075044,SLC22A29,solute carrier family 22. member 29,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,1.21,10,0.3,1.35,0.3,2.38,2.38,0.129,0,0,-0.5,1.6
ENSMUSG00000060572,MFAP2,microfibrillar-associated protein 2,microfibril|extracellular region|proteinaceous extracellular matrix|,platelet formation|,fibronectin binding|protein binding|fibrinogen binding|,10,0.5,3.88,10,0,0,0.5,2.36,2.36,0.131,0,0,-0.5,1.7
ENSMUSG00000090550,PRLH,prolactin releasing hormone,cytoplasm|,tissue homeostasis|response to dietary excess|reduction of food intake in response to dietary excess|energy reserve metabolic process|lipid metabolic process|G-protein coupled receptor signaling pathway|feeding behavior|response to glucose|response to insulin|regulation of multicellular organism growth|eating behavior|response to peptide hormone|fat cell differentiation|autonomic nervous system development|,neuropeptide hormone activity|prolactin-releasing peptide receptor binding|,10,-0.2,1.5,10,-0.2,1.04,-0.2,2.36,-2.36,0.131,0,0,-1.6,0.5
ENSMUSG00000050075,GPR171,G protein-coupled receptor 171,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.6,4.33,10,0,0,0.4,2.35,2.35,0.131,0,0,-0.5,1.7
ENSMUSG00000056223,SPATA31,spermatogenesis associated 31,acrosomal vesicle|membrane|integral component of membrane|cytoplasmic vesicle|,spermatogenesis|biological_process|cell differentiation|,actin binding|,10,-0.3,2.92,10,0,0,-0.3,2.35,-2.35,0.131,0,0,-1.4,0.8
ENSMUSG00000066196,SPAG8,sperm associated antigen 8,acrosomal vesicle|nucleus|cytoplasm|,positive regulation of protein binding|positive regulation of transcription from RNA polymerase II promoter|,protein binding|,10,0.5,3.67,10,0.1,0.115,0.3,2.35,2.35,0.131,0,0,-0.6,1.6
ENSMUSG00000073111,OLFR446,olfactory receptor 446,integral component of membrane|,G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,olfactory receptor activity|,10,-0.3,2.19,10,-0.2,0.496,-0.3,2.35,-2.35,0.131,0,0,-1.5,0.7
ENSMUSG00000049674,OLFR714,olfactory receptor 714,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.7,3.98,10,0.9,0.885,-0.7,2.35,-2.35,0.131,0,0,-1.9,1.2
ENSMUSG00000044022,PCDHB21,protocadherin beta 21,plasma membrane|membrane|integral component of membrane|,cell adhesion|,molecular_function|,10,-0.5,2.65,10,-0.2,0.153,-0.3,2.35,-2.35,0.131,0,0,-1.6,0.9
ENSMUSG00000060332,TMC2,transmembrane channel-like gene family 2,membrane|integral component of membrane|stereocilium bundle tip|,transport|ion transport|regulation of ion transmembrane transport|detection of mechanical stimulus involved in sensory perception of sound|vestibular reflex|calcium ion transmembrane transport|calcium ion transmembrane transport|,voltage-gated calcium channel activity|voltage-gated calcium channel activity|,10,-0.3,1.58,10,-0.2,1.01,-0.2,2.34,-2.34,0.132,0,0,-1.6,0.5
ENSMUSG00000060787,OLFR464,olfactory receptor 464,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.239,10,0.5,2.38,0.3,2.33,2.33,0.133,0,0,-0.4,1.6
ENSMUSG00000046862,PRAMEF8,PRAME family member 8,cellular_component|,biological_process|,molecular_function|,10,0.3,1.81,10,0.2,0.727,0.3,2.33,2.33,0.133,0,0,-0.4,1.6
ENSMUSG00000067786,NNAT,neuronatin,cytoplasm|,multicellular organismal development|brain development|response to glucose|positive regulation of insulin secretion|regulation of protein localization|,None,10,-0.4,3.98,10,0,0,-0.4,2.33,-2.33,0.133,0,0,-1.6,0.5
ENSMUSG00000036242,3632451O06RIK,RIKEN cDNA 3632451O06 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.5,1.89,10,-0.2,0.947,-0.3,2.32,-2.32,0.133,0,0,-1.5,0.8
ENSMUSG00000012042,4930579F01RIK,RIKEN cDNA 4930579F01 gene,cellular_component|,biological_process|,molecular_function|,10,-0.4,3.95,10,0,0,-0.3,2.32,-2.32,0.133,0,0,-1.8,0.4
ENSMUSG00000034641,CD300LD,CD300 molecule-like family member d,plasma membrane|membrane|integral component of membrane|,immune system process|regulation of interleukin-6 production|regulation of tumor necrosis factor production|,protein binding|,10,-0.4,3.18,10,-1.2,1.02,-0.5,2.3,-2.3,0.135,0,0,-2,0.3
ENSMUSG00000038457,TMEM255B,transmembrane protein 255B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,2.17,9,-0.2,0.34,-0.2,2.3,-2.3,0.135,0,0,-1.7,0.7
ENSMUSG00000022800,FYTTD1,forty-two-three domain containing 1,nucleus|nucleoplasm|nuclear speck|,mRNA export from nucleus|transport|mRNA transport|,RNA binding|mRNA binding|poly(A) RNA binding|,10,-0.4,1.27,10,-0.2,1.47,-0.2,2.3,-2.3,0.135,0,0,-1.7,0.2
ENSMUSG00000018381,ABI3,"ABI gene family, member 3",intracellular|cytoplasm|membrane|lamellipodium|,regulation of cell migration|,molecular_function|,10,0.3,1.83,10,0.2,0.729,0.3,2.28,2.28,0.136,0,0,-0.8,1.4
ENSMUSG00000067882,CASP16,"caspase 16, apoptosis-related cysteine peptidase",cytoplasm|,proteolysis|intrinsic apoptotic signaling pathway in response to DNA damage|extrinsic apoptotic signaling pathway in absence of ligand|,cysteine-type endopeptidase activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0.4,2.75,10,0.2,0.229,0.3,2.27,2.27,0.137,0,0,-1.1,1.6
ENSMUSG00000059994,FCRL1,Fc receptor-like 1,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.56,10,-0.3,0.875,-0.3,2.26,-2.26,0.138,0,0,-1.6,0.5
ENSMUSG00000033765,CALM4,calmodulin 4,extracellular vesicular exosome|,None,calcium ion binding|metal ion binding|,10,-0.1,0.314,10,-0.4,2.66,-0.3,2.25,-2.25,0.139,0,0,-1.4,1.3
ENSMUSG00000073804,NPS,neuropeptide S,extracellular region|,"neuropeptide signaling pathway|visual learning|positive regulation of synaptic transmission, GABAergic|positive regulation of action potential|positive regulation of synaptic transmission, glutamatergic|",molecular_function|,10,0.3,1.42,10,0.4,1.12,0.3,2.25,2.25,0.139,0,0,-0.9,1.5
ENSMUSG00000002803,BTBD6,BTB (POZ) domain containing 6,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.5,4,10,0,0,0.4,2.24,2.24,0.139,0,0,-0.5,1.6
ENSMUSG00000050493,FAM167B,"family with sequence similarity 167, member B",cellular_component|,biological_process|,molecular_function|,10,-0.5,4.71,10,0.3,1.08,-0.5,2.24,-2.24,0.139,0,0,-1.6,0.9
ENSMUSG00000091151,VMN1R224,vomeronasal 1 receptor 224,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.75,10,0.7,3.46,0.4,2.23,2.23,0.14,0,0,-1.2,1.7
ENSMUSG00000058515,OLFR933,olfactory receptor 933,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.6,1.31,10,0.8,2.19,0.2,2.23,2.23,0.14,0,0,-1.2,1.8
ENSMUSG00000094995,GM17365,"predicted gene, 17365",extracellular region|,None,None,4,0.6,1.57,4,-0.4,1.51,-0.3,2.22,-2.22,0.141,0,0,-1.7,1.7
ENSMUSG00000029184,OLFR109,olfactory receptor 109,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.5,2.98,10,-0.3,0.587,-0.4,2.21,-2.21,0.142,0,0,-1.3,1.4
ENSMUSG00000024810,IL33,interleukin 33,extracellular region|extracellular space|nucleus|chromosome|cytoplasmic vesicle|,"negative regulation of leukocyte migration|negative regulation of T-helper 1 type immune response|positive regulation of type 2 immune response|transcription, DNA-templated|positive regulation of gene expression|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|negative regulation of interferon-gamma production|positive regulation of interleukin-13 production|positive regulation of interleukin-4 production|positive regulation of interleukin-5 production|positive regulation of interleukin-6 production|positive regulation of macrophage activation|positive regulation of macrophage activation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of inflammatory response|positive regulation of immunoglobulin secretion|negative regulation of immunoglobulin secretion|positive regulation of chemokine secretion|positive regulation of chemokine secretion|extrinsic apoptotic signaling pathway|",cytokine activity|cytokine activity|cytokine activity|,10,-0.4,2.79,10,0.6,2,-0.4,2.2,-2.2,0.143,0,0,-2,0.8
ENSMUSG00000086277,4930558K02RIK,RIKEN cDNA 4930558K02 gene,cellular_component|,biological_process|,molecular_function|,10,0.4,2.82,10,-0.4,1.29,0.3,2.2,2.2,0.143,0,0,-1,1.6
ENSMUSG00000096059,IFNA6,interferon alpha 6,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,10,-0.3,3.02,10,0.4,1.9,-0.2,2.19,-2.19,0.143,0,0,-1.5,1.2
ENSMUSG00000042219,OLFR631,olfactory receptor 631,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,0.782,10,-0.5,1.64,-0.3,2.19,-2.19,0.143,0,0,-1.8,0.4
ENSMUSG00000062061,OBP2A,odorant binding protein 2A,cellular_component|extracellular region|,transport|biological_process|,molecular_function|,10,0.3,1.5,10,0.3,0.84,0.3,2.18,2.18,0.144,0,0,-0.6,1.6
ENSMUSG00000045812,OLFR984,olfactory receptor 984,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,2.95,10,0,0,0.3,2.18,2.18,0.144,0,0,-0.4,1.8
ENSMUSG00000042816,GPR151,G protein-coupled receptor 151,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.3,1.58,10,0.2,0.836,0.3,2.17,2.17,0.145,0,0,-0.8,1.6
ENSMUSG00000091055,SIGLEC15,sialic acid binding Ig-like lectin 15,plasma membrane|protein complex|,regulation of actin cytoskeleton organization|regulation of bone resorption|cellular response to lipoprotein particle stimulus|regulation of osteoclast development|regulation of osteoclast development|,protein binding|,10,0.6,4.71,10,0,0,0.5,2.17,2.17,0.145,0,0,-0.4,1.8
ENSMUSG00000029298,GBP9,guanylate-binding protein 9,symbiont-containing vacuole membrane|cytoplasmic vesicle|extracellular vesicular exosome|,defense response to protozoan|adhesion of symbiont to host|defense response to Gram-positive bacterium|cellular response to interferon-gamma|,molecular_function|,10,0,0,10,-0.4,3,-0.3,2.16,-2.16,0.146,0,0,-1.2,1.5
ENSMUSG00000067219,NIPAL1,NIPA-like domain containing 1,cellular_component|membrane|integral component of membrane|,transport|ion transport|magnesium ion transport|,molecular_function|magnesium ion transmembrane transporter activity|,10,0.4,3.88,10,0,0,0.4,2.15,2.15,0.147,0,0,-0.5,1.6
ENSMUSG00000066684,PILRB1,paired immunoglobin-like type 2 receptor beta 1,plasma membrane|membrane|integral component of membrane|,myeloid dendritic cell activation|negative regulation of osteoclast differentiation|,protein binding|MHC class I protein binding|,10,-0.5,3.93,10,0,0,-0.4,2.14,-2.14,0.148,0,0,-1.6,0.4
ENSMUSG00000007908,HMGCLL1,3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1,cytoplasm|endoplasmic reticulum|cytosol|membrane|perinuclear region of cytoplasm|,ketone body biosynthetic process|,catalytic activity|hydroxymethylglutaryl-CoA lyase activity|lyase activity|metal ion binding|,10,0.3,1.39,10,0.8,1.76,0.2,2.13,2.13,0.149,0,0,-0.3,1.9
ENSMUSG00000011008,MCOLN2,mucolipin 2,membrane|integral component of membrane|,transport|ion transport|,None,10,-0.3,1.68,10,-0.2,0.619,-0.2,2.13,-2.13,0.149,0,0,-1.5,0.6
ENSMUSG00000091531,OLFR102,olfactory receptor 102,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.03,10,0.3,1.27,0.3,2.13,2.13,0.149,0,0,-0.6,1.6
ENSMUSG00000044708,KCNJ10,"potassium inwardly-rectifying channel, subfamily J, member 10",plasma membrane|integral component of plasma membrane|microvillus|membrane|integral component of membrane|basolateral plasma membrane|basolateral plasma membrane|apical plasma membrane|astrocyte projection|,transport|ion transport|potassium ion transport|visual perception|adult walking behavior|potassium ion import|oligodendrocyte development|central nervous system myelination|regulation of ion transmembrane transport|regulation of membrane potential|regulation of long-term neuronal synaptic plasticity|protein homotetramerization|regulation of sensory perception of pain|L-glutamate uptake involved in synaptic transmission|L-glutamate import|potassium ion homeostasis|regulation of resting membrane potential|membrane hyperpolarization|potassium ion transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,nucleotide binding|receptor binding|inward rectifier potassium channel activity|inward rectifier potassium channel activity|voltage-gated ion channel activity|potassium channel activity|protein binding|ATP binding|identical protein binding|,10,-0.3,2.89,10,-0.1,0.0976,-0.3,2.12,-2.12,0.15,0,0,-1.5,0.6
ENSMUSG00000073962,OLFR576,olfactory receptor 576,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,0.641,10,1,2.55,0.8,2.12,2.12,0.15,0,0,-0.1,2
ENSMUSG00000031430,VSIG1,V-set and immunoglobulin domain containing 1,plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|,epithelial cell morphogenesis|maintenance of gastrointestinal epithelium|,molecular_function|,10,0.4,0.232,10,-0.4,3.04,-0.4,2.12,-2.12,0.15,0,0,-1.6,0.8
ENSMUSG00000096131,KRTAP10-10,keratin associated protein 10-10,cellular_component|,biological_process|,molecular_function|,10,-0.4,2.63,10,-0.1,0.108,-0.3,2.12,-2.12,0.15,0,0,-1.6,0.5
ENSMUSG00000024682,GIF,gastric intrinsic factor,extracellular region|extracellular space|endosome|microvillus|apical plasma membrane|,transport|ion transport|cobalt ion transport|cobalamin metabolic process|cobalamin metabolic process|cobalamin transport|,cobalamin binding|cobalamin binding|,10,-0.1,0.15,10,0.5,3.03,0.5,2.11,2.11,0.15,0,0,-0.8,1.7
ENSMUSG00000062732,LYPD4,Ly6/Plaur domain containing 4,cellular_component|plasma membrane|membrane|anchored component of membrane|,biological_process|,molecular_function|,10,0.5,1.49,10,0.4,0.799,0.5,2.11,2.11,0.15,0,0,-0.7,1.6
ENSMUSG00000045306,OLFR734,olfactory receptor 734,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.7,4.56,10,0,0,0.7,2.11,2.11,0.15,0,0,-0.3,2
ENSMUSG00000044816,D630023F18RIK,RIKEN cDNA D630023F18 gene,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.31,10,0.7,2.94,-0.3,2.11,-2.11,0.15,0,0,-1.2,1.7
ENSMUSG00000000202,BTBD17,BTB (POZ) domain containing 17,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.7,2.15,10,-0.1,0.169,-0.7,2.11,-2.11,0.15,0,0,-1.9,0.2
ENSMUSG00000059473,OLFR979,olfactory receptor 979,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.8,4.16,10,-0.4,0.699,0.5,2.1,2.1,0.151,0,0,-1,1.9
ENSMUSG00000022519,SRL,sarcalumenin,sarcoplasmic reticulum|,None,GTPase activity|GTP binding|,10,0.2,2.12,10,0.1,0.202,0.2,2.09,2.09,0.152,0,0,-0.9,1.4
ENSMUSG00000027661,SLC2A10,"solute carrier family 2 (facilitated glucose transporter), member 10",cytoplasm|integral component of plasma membrane|membrane|integral component of membrane|,transport|carbohydrate transport|glucose transport|hexose transmembrane transport|transmembrane transport|,transporter activity|glucose transmembrane transporter activity|transmembrane transporter activity|substrate-specific transmembrane transporter activity|,10,0.2,0.593,10,0.5,2.3,0.4,2.08,2.08,0.153,0,0,-0.6,1.6
ENSMUSG00000057179,OLFR747,olfactory receptor 747,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,3.48,10,0.2,0.323,-0.5,2.07,-2.07,0.154,0,0,-1.6,1.1
ENSMUSG00000074949,OLFR1310,olfactory receptor 1310,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,1.45,10,-0.2,0.777,-0.2,2.07,-2.07,0.154,0,0,-1.5,0.8
ENSMUSG00000049315,OLFR348,olfactory receptor 348,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,2.16,10,0.8,1.08,0.4,2.07,2.07,0.154,0,0,-1.4,1.7
ENSMUSG00000039492,CCDC27,coiled-coil domain containing 27,cellular_component|,biological_process|,molecular_function|,10,0.2,0.892,10,0.5,1.44,0.2,2.06,2.06,0.155,0,0,-0.7,1.6
ENSMUSG00000044084,4933402P03RIK,RIKEN cDNA 4933402P03 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.241,10,0.5,3.11,0.4,2.05,2.05,0.156,0,0,-0.3,1.7
ENSMUSG00000053815,OLFR744,olfactory receptor 744,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.8,2.16,10,-0.4,1.37,-0.3,2.04,-2.04,0.157,0,0,-1.4,1.7
ENSMUSG00000034435,TMEM30B,transmembrane protein 30B,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|lipid transport|positive regulation of protein exit from endoplasmic reticulum|,molecular_function|,10,0.5,3.26,10,0.1,0.0446,0.3,2.03,2.03,0.158,0,0,-0.4,1.7
ENSMUSG00000060044,TMEM26,transmembrane protein 26,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.4,4.36,0.3,2.02,2.02,0.159,0,0,-0.5,1.7
ENSMUSG00000047161,CHST9,carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9,Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|sulfur compound metabolic process|carbohydrate biosynthetic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",9,-0.3,0.674,9,-0.5,1.52,-0.5,2.02,-2.02,0.159,0,0,-1.8,0.5
ENSMUSG00000044378,SLC15A5,"solute carrier family 15, member 5",cellular_component|membrane|integral component of membrane|,transport|biological_process|protein transport|peptide transport|,molecular_function|transporter activity|symporter activity|,10,0.5,4.09,10,-1.2,3.02,0.4,2.01,2.01,0.16,0,0,-2,1.1
ENSMUSG00000020169,BEST3,bestrophin 3,plasma membrane|membrane|integral component of membrane|chloride channel complex|,transport|ion transport|chloride transport|inorganic anion transport|negative regulation of ion transport|chloride transmembrane transport|,chloride channel activity|,10,-0.3,1.8,10,-0.1,0.489,-0.3,2,-2,0.161,0,0,-1.5,0.6
ENSMUSG00000046460,SH2D7,SH2 domain containing 7,cellular_component|,biological_process|,molecular_function|,10,-0.2,2.5,10,1.1,2.51,-0.2,2,-2,0.161,0,0,-1,2
ENSMUSG00000040514,4921511H03RIK,RIKEN cDNA 4921511H03 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,3.03,10,0.1,0.0135,0.3,2,2,0.161,0,0,-0.8,1.6
ENSMUSG00000041771,SLC24A4,"solute carrier family 24 (sodium/potassium/calcium exchanger), member 4",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|sodium ion transport|calcium ion transport|sensory perception of smell|sodium ion transmembrane transport|response to stimulus|transmembrane transport|calcium ion transmembrane transport|potassium ion transmembrane transport|amelogenesis|,"calcium:sodium antiporter activity|calcium, potassium:sodium antiporter activity|symporter activity|antiporter activity|",10,0.3,1.64,10,0.2,0.568,0.3,1.99,1.99,0.162,0,0,-0.7,1.6
ENSMUSG00000028007,SNX7,sorting nexin 7,endosome|membrane|cytoplasmic vesicle|,transport|intracellular protein transport|apoptotic process|protein transport|,lipid binding|phosphatidylinositol binding|,10,-0.1,0.116,10,0.3,4.15,0.3,1.99,1.99,0.162,0,0,-0.7,1.6
ENSMUSG00000062757,OLFR1206,olfactory receptor 1206,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,3.46,10,0,0,0.2,1.98,1.98,0.163,0,0,-0.6,1.6
ENSMUSG00000020279,IL9R,interleukin 9 receptor,extracellular region|plasma membrane|membrane|integral component of membrane|,positive regulation of cell growth|interleukin-9-mediated signaling pathway|,cytokine receptor activity|interleukin-9 receptor activity|interleukin-9 binding|,10,0.2,0.288,10,0.3,1.86,0.2,1.98,1.98,0.163,0,0,-1.8,1.2
ENSMUSG00000022661,CD200,CD200 antigen,plasma membrane|membrane|integral component of membrane|,None,protein binding|,10,-0.2,1.33,10,-0.3,0.837,-0.3,1.97,-1.97,0.164,0,0,-1.8,0.4
ENSMUSG00000060878,OLFR1420,olfactory receptor 1420,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,2.36,10,0.1,0.179,-0.3,1.96,-1.96,0.165,0,0,-1.6,0.7
ENSMUSG00000029195,KLB,klotho beta,plasma membrane|membrane|integral component of membrane|,carbohydrate metabolic process|positive regulation of cell proliferation|fibroblast growth factor receptor signaling pathway|positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway|,"hydrolase activity, hydrolyzing O-glycosyl compounds|fibroblast growth factor binding|",10,0.6,3.6,10,0.1,0.131,0.4,1.96,1.96,0.165,0,0,-1,1.8
ENSMUSG00000079559,GM684,predicted gene 684,cellular_component|,biological_process|,molecular_function|,10,-0.4,1,10,0.5,2.01,0.3,1.96,1.96,0.165,0,0,-1,1.5
ENSMUSG00000059382,TAS2R120,"taste receptor, type 2, member 120",cellular_component|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|bitter taste receptor activity|,10,0.1,0.16,10,0.4,2.18,0.2,1.96,1.96,0.165,0,0,-0.6,1.6
ENSMUSG00000071890,MROH9,maestro heat-like repeat family member 9,cellular_component|,biological_process|,molecular_function|,10,0.1,0.122,10,0.3,2.32,0.3,1.95,1.95,0.166,0,0,-0.9,1.5
ENSMUSG00000028268,GBP3,guanylate binding protein 3,nucleus|cytoplasm|cytosol|symbiont-containing vacuole membrane|cytoplasmic vesicle|,GTP catabolic process|cellular response to interferon-beta|defense response to protozoan|adhesion of symbiont to host|defense response to Gram-positive bacterium|cellular response to interferon-gamma|,nucleotide binding|GTPase activity|GTP binding|,10,0.2,0.175,10,-0.9,4.85,-0.9,1.95,-1.95,0.166,0,0,-2,0.3
ENSMUSG00000018776,SLC35G3,"solute carrier family 35, member G3",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.4,2.85,0.3,1.94,1.94,0.167,0,0,-1,1.5
ENSMUSG00000057761,OLFR1022,olfactory receptor 1022,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.7,3.92,10,-0.1,0.315,-0.7,1.93,-1.93,0.168,0,0,-2,0.8
ENSMUSG00000045534,KCNA5,"potassium voltage-gated channel, shaker-related subfamily, member 5",endoplasmic reticulum|Golgi apparatus|plasma membrane|plasma membrane|integral component of plasma membrane|voltage-gated potassium channel complex|intercalated disc|intercalated disc|membrane|integral component of membrane|Z disc|membrane raft|intracellular canaliculus|perinuclear region of cytoplasm|,transport|ion transport|potassium ion transport|potassium ion transport|regulation of vasoconstriction|regulation of ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|regulation of potassium ion transport|negative regulation of potassium ion transport|protein oligomerization|protein homooligomerization|negative regulation of cytosolic calcium ion concentration|potassium ion homeostasis|transmembrane transport|membrane hyperpolarization|regulation of atrial cardiac muscle cell membrane repolarization|potassium ion export|potassium ion transmembrane transport|membrane repolarization during cardiac muscle cell action potential|atrial cardiac muscle cell action potential|regulation of heart rate by cardiac conduction|positive regulation of G1/S transition of mitotic cell cycle|positive regulation of myoblast proliferation|,receptor binding|ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|protein binding|outward rectifier potassium channel activity|potassium channel inhibitor activity|protein kinase binding|alpha-actinin binding|voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|scaffold protein binding|,10,-0.2,0.902,9,-0.7,1.34,-0.2,1.92,-1.92,0.169,0,0,-1.8,1.1
ENSMUSG00000051050,SPINK14,"serine peptidase inhibitor, Kazal type 14",cellular_component|,biological_process|,molecular_function|,10,-0.4,3.94,10,0.3,0.651,-0.4,1.91,-1.91,0.17,0,0,-1.6,0.8
ENSMUSG00000034883,LRR1,leucine rich repeat protein 1,cellular_component|,biological_process|,molecular_function|isomerase activity|,5,-0.5,2.3,5,0.5,1.84,0.4,1.9,1.9,0.171,0,0,-1.6,1.7
ENSMUSG00000079298,KLRB1B,killer cell lectin-like receptor subfamily B member 1B,plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,negative regulation of natural killer cell mediated cytotoxicity|negative regulation of natural killer cell mediated cytotoxicity|,receptor activity|protein binding|carbohydrate binding|protein homodimerization activity|,9,-0.3,1.68,9,-0.2,0.553,-0.2,1.9,-1.9,0.171,0,0,-1.7,0.7
ENSMUSG00000031075,ANO1,"anoctamin 1, calcium activated chloride channel",cytoplasm|plasma membrane|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|apical plasma membrane|chloride channel complex|extracellular vesicular exosome|,transport|ion transport|cation transport|chloride transport|chloride transport|multicellular organismal development|regulation of membrane potential|regulation of membrane potential|trachea development|chloride transmembrane transport|chloride transmembrane transport|,calcium activated cation channel activity|intracellular calcium activated chloride channel activity|intracellular calcium activated chloride channel activity|chloride channel activity|protein homodimerization activity|protein heterodimerization activity|,10,0.1,0.116,10,0.3,2.36,0.3,1.9,1.9,0.171,0,0,-0.5,1.7
ENSMUSG00000033082,CLEC1A,"C-type lectin domain family 1, member a",cellular_component|membrane|integral component of membrane|,biological_process|,carbohydrate binding|,10,-1.3,5.04,10,0,0,-1.3,1.89,-1.89,0.172,0,0,-2,1
ENSMUSG00000022494,SHISA9,shisa family member 9,plasma membrane|ionotropic glutamate receptor complex|membrane|integral component of membrane|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|dendritic spine membrane|cell projection|synapse|,regulation of short-term neuronal synaptic plasticity|,molecular_function|,10,0.2,1.57,10,0.3,0.539,0.2,1.89,1.89,0.172,0,0,-1.2,1.4
ENSMUSG00000030158,CLEC12B,"C-type lectin domain family 12, member B",cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,carbohydrate binding|,10,-1.1,2.29,10,-0.5,0.481,-0.9,1.88,-1.88,0.173,0,0,-2,0.7
ENSMUSG00000028008,ASIC5,acid-sensing (proton-gated) ion channel family member 5,plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|proton transport|sodium ion transmembrane transport|sodium ion transmembrane transport|,sodium channel activity|hydrogen ion channel activity|ligand-gated sodium channel activity|,10,0.2,1.29,10,0.8,1.82,0.2,1.87,1.87,0.174,0,0,-0.7,1.9
ENSMUSG00000032024,CLMP,CXADR-like membrane protein,cytoplasmic microtubule|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,digestive tract development|,molecular_function|,10,0.4,3.09,10,-0.2,0.704,0.3,1.87,1.87,0.174,0,0,-1,1.4
ENSMUSG00000009487,OTOG,otogelin,extracellular region|proteinaceous extracellular matrix|cytosol|plasma membrane|membrane|,cell adhesion|blood coagulation|sensory perception of sound|adult locomotory behavior|L-arabinose metabolic process|,structural molecule activity|alpha-L-arabinofuranosidase activity|,10,-0.3,2.88,10,0,0,-0.2,1.87,-1.87,0.174,0,0,-1.8,0.5
ENSMUSG00000028019,PDGFC,"platelet-derived growth factor, C polypeptide",extracellular region|extracellular space|nucleus|cytoplasm|plasma membrane|cell surface|membrane|extracellular vesicular exosome|,activation of transmembrane receptor protein tyrosine kinase activity|multicellular organismal development|positive regulation of cell proliferation|organ morphogenesis|organ morphogenesis|positive regulation of DNA replication|platelet-derived growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|positive regulation of fibroblast proliferation|regulation of peptidyl-tyrosine phosphorylation|positive regulation of cell division|cellular response to amino acid stimulus|,platelet-derived growth factor receptor binding|platelet-derived growth factor receptor binding|growth factor activity|protein homodimerization activity|,10,0.5,3.88,10,0,0,0.4,1.86,1.86,0.175,0,0,-1.3,1.6
ENSMUSG00000078260,GM11569,predicted gene 11569,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.3,1.64,10,-0.2,0.499,-0.3,1.86,-1.86,0.175,0,0,-1.6,0.6
ENSMUSG00000026063,PIH1D3,PIH1 domain containing 3,cytoplasm|,sperm motility|axonemal dynein complex assembly|,protein binding|chaperone binding|,10,0.9,3.68,10,-0.1,0.299,-0.3,1.85,-1.85,0.176,0,0,-0.9,1.9
ENSMUSG00000096421,GM10100,predicted gene 10100,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.2,1.86,10,0.2,0.122,0.2,1.85,1.85,0.176,0,0,-0.5,1.7
ENSMUSG00000078315,FAM47C,"family with sequence similarity 47, member C",cellular_component|,biological_process|,molecular_function|,10,-0.3,1.36,10,-0.2,0.654,-0.3,1.85,-1.85,0.176,0,0,-1.6,0.8
ENSMUSG00000054320,LRRC36,leucine rich repeat containing 36,cellular_component|,biological_process|,molecular_function|,10,0.4,2.03,10,0.1,0.145,0.5,1.85,1.85,0.176,0,0,-0.5,1.8
ENSMUSG00000029288,AMBN,ameloblastin,extracellular region|proteinaceous extracellular matrix|,cell adhesion|cell proliferation|extracellular matrix organization|biomineral tissue development|odontogenesis of dentin-containing tooth|,growth factor activity|extracellular matrix structural constituent conferring compression resistance|structural constituent of tooth enamel|,9,0.3,1.56,9,0.2,0.501,0.3,1.84,1.84,0.177,0,0,-0.8,1.6
ENSMUSG00000095138,OLFR781,olfactory receptor 781,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,2.75,10,0.4,1.79,-0.3,1.84,-1.84,0.177,0,0,-1.6,1.1
ENSMUSG00000024008,CPNE5,copine V,neuron projection|neuronal cell body|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.3,1.86,10,-0.2,0.213,-0.3,1.84,-1.84,0.177,0,0,-1.8,0.8
ENSMUSG00000014980,TSEN15,tRNA splicing endonuclease 15 homolog (S. cerevisiae),cellular_component|nucleus|,"tRNA splicing, via endonucleolytic cleavage and ligation|mRNA processing|tRNA processing|biological_process|",tRNA-intron endonuclease activity|molecular_function|,10,-0.2,0.553,10,0.8,2.81,0.4,1.83,1.83,0.179,0,0,-0.9,1.8
ENSMUSG00000031449,ATP4B,"ATPase, H+/K+ exchanging, beta polypeptide",endoplasmic reticulum|plasma membrane|sodium:potassium-exchanging ATPase complex|membrane|integral component of membrane|,ATP catabolic process|transport|ion transport|potassium ion transport|sodium ion transport|cell adhesion|regulation of proton transport|proton transport|protein glycosylation in endoplasmic reticulum|pH reduction|potassium ion transmembrane transport|hydrogen ion transmembrane transport|,hydrogen:potassium-exchanging ATPase activity|protein heterodimerization activity|,10,0.4,2.7,10,0.1,0.245,0.3,1.83,1.83,0.179,0,0,-0.7,1.6
ENSMUSG00000078719,MSMP,"microseminoprotein, prostate associated",extracellular region|extracellular space|cytoplasm|,biological_process|,molecular_function|,10,-0.3,2.57,10,0.2,0.347,-0.3,1.82,-1.82,0.18,0,0,-1.8,0.9
ENSMUSG00000049168,OLFR449,olfactory receptor 449,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1.1,0.531,10,0.7,3.62,0.4,1.81,1.81,0.181,0,0,-1.3,1.9
ENSMUSG00000027676,CCDC39,coiled-coil domain containing 39,cytoplasm|cytoskeleton|cilium|axoneme|cell projection|,heart looping|lung development|determination of pancreatic left/right asymmetry|cilium-dependent cell motility|epithelial cilium movement involved in determination of left/right asymmetry|axonemal dynein complex assembly|determination of digestive tract left/right asymmetry|determination of liver left/right asymmetry|,molecular_function|,10,0.3,1.96,10,0.1,0.131,0.3,1.8,1.8,0.182,0,0,-1,1.5
ENSMUSG00000075192,OLFR1053,olfactory receptor 1053,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|,10,0.2,0.886,10,0.3,1.06,0.3,1.8,1.8,0.182,0,0,-1,1.5
ENSMUSG00000073896,OLFR716,olfactory receptor 716,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,2.99,10,0,0,0.3,1.8,1.8,0.182,0,0,-0.7,1.7
ENSMUSG00000042788,FAM166B,"family with sequence similarity 166, member B",cellular_component|,biological_process|,molecular_function|,10,0.4,3.51,10,-0.1,0.152,0.4,1.79,1.79,0.183,0,0,-0.6,1.6
ENSMUSG00000026679,ENKUR,"enkurin, TRPC channel interacting protein",cilium|cell projection|,None,calmodulin binding|SH3 domain binding|,10,0.4,2.15,10,0.2,0.213,0.3,1.79,1.79,0.183,0,0,-1.6,1.1
ENSMUSG00000074695,IL22,interleukin 22,extracellular region|extracellular space|,regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|negative regulation of inflammatory response|reactive oxygen species metabolic process|,cytokine activity|protein binding|,10,-0.6,4.29,10,0.1,0.0307,-0.3,1.79,-1.79,0.183,0,0,-1.8,0.4
ENSMUSG00000031342,GPM6B,glycoprotein m6b,plasma membrane|membrane|integral component of membrane|membrane raft|,ossification|transport|protein transport|positive regulation of bone mineralization|regulation of actin cytoskeleton organization|negative regulation of serotonin uptake|regulation of focal adhesion assembly|extracellular matrix assembly|negative regulation of protein localization to cell surface|,None,10,-0.4,1.89,10,-0.2,0.272,-0.3,1.79,-1.79,0.183,0,0,-1.7,0.5
ENSMUSG00000075140,OLFR73,olfactory receptor 73,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|sensory perception of smell|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|olfactory receptor activity|odorant binding|,10,-0.4,2.67,10,0.2,0.943,0.2,1.79,1.79,0.183,0,0,-1.5,1
ENSMUSG00000061859,INADL,InaD-like (Drosophila),cytoplasm|plasma membrane|tight junction|membrane|cell junction|protein complex|apical part of cell|perinuclear region of cytoplasm|extracellular vesicular exosome|,None,protein binding|,10,0.2,0.906,10,-0.5,2.97,-0.4,1.78,-1.78,0.184,0,0,-1.6,1
ENSMUSG00000063765,CHADL,chondroadherin-like,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.38,10,-0.2,0.532,-0.2,1.78,-1.78,0.184,0,0,-1.6,0.7
ENSMUSG00000032503,ARPP21,"cyclic AMP-regulated phosphoprotein, 21",cytoplasm|,cellular response to heat|,molecular_function|nucleic acid binding|calmodulin binding|,10,0.3,0.548,10,0.2,1.41,0.2,1.77,1.77,0.186,0,0,-0.7,1.6
ENSMUSG00000063157,CSN2,casein beta,extracellular region|extracellular space|,transport|lactation|,transporter activity|,10,-0.2,1.31,10,0.6,0.75,-0.3,1.77,-1.77,0.186,0,0,-1.7,1.1
ENSMUSG00000096404,OLFR1359,olfactory receptor 1359,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,2.53,10,0,0,0.3,1.76,1.76,0.187,0,0,-0.7,1.6
ENSMUSG00000029861,FAM131B,"family with sequence similarity 131, member B",cellular_component|,biological_process|,molecular_function|,10,1.1,3.54,10,0.2,0.716,1,1.76,1.76,0.187,0,0,-0.1,2
ENSMUSG00000021097,CLMN,calmin,cytoplasm|membrane|integral component of membrane|,negative regulation of cell proliferation|neuron projection development|,molecular_function|actin binding|,10,0.3,2.53,10,0.1,0.0758,0.3,1.76,1.76,0.187,0,0,-0.4,1.8
ENSMUSG00000023873,1700010I14RIK,RIKEN cDNA 1700010I14 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.372,10,-0.8,2.98,-0.3,1.76,-1.76,0.187,0,0,-1.9,0.5
ENSMUSG00000049608,GPR55,G protein-coupled receptor 55,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|activation of phospholipase C activity|positive regulation of Rho protein signal transduction|cannabinoid signaling pathway|bone resorption|negative regulation of osteoclast differentiation|positive regulation of ERK1 and ERK2 cascade|,signal transducer activity|G-protein coupled receptor activity|cannabinoid receptor activity|,10,0.2,1.44,10,0.3,0.52,0.2,1.76,1.76,0.187,0,0,-1,1.5
ENSMUSG00000042386,TEX13,testis expressed gene 13,cellular_component|,biological_process|,molecular_function|,10,-0.3,2.05,10,-0.1,0.228,-0.2,1.76,-1.76,0.187,0,0,-1.7,0.7
ENSMUSG00000035681,KCNC2,"potassium voltage gated channel, Shaw-related subfamily, member 2",voltage-gated potassium channel complex|membrane|integral component of membrane|,action potential|transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,9,-0.4,2.96,9,0,0,-0.2,1.76,-1.76,0.187,0,0,-1.8,0.5
ENSMUSG00000094496,OLFR792,olfactory receptor 792,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.03,10,0.4,1.7,0.2,1.76,1.76,0.187,0,0,-1,1.6
ENSMUSG00000063626,UNC5D,unc-5 homolog D (C. elegans),cell surface|membrane|integral component of membrane|,apoptotic process|signal transduction|multicellular organismal development|axon guidance|pyramidal neuron differentiation|regulation of neuron migration|,protein binding|,10,-0.2,1.28,10,-0.2,0.617,-0.2,1.75,-1.75,0.188,0,0,-1.6,0.7
ENSMUSG00000058252,1700008I05RIK,RIKEN cDNA 1700008I05 gene,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.02,10,-0.2,0.882,-0.2,1.75,-1.75,0.188,0,0,-1.2,1.9
ENSMUSG00000075377,OLFR362,olfactory receptor 362,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.136,10,-0.8,3.36,-0.3,1.74,-1.74,0.189,0,0,-2,0.7
ENSMUSG00000029206,NSUN7,"NOL1/NOP2/Sun domain family, member 7",None,methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|RNA binding|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,0.9,4.54,10,0,0,0.9,1.73,1.73,0.19,0,0,-0.6,2
ENSMUSG00000075384,OLFR3,olfactory receptor 3,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.7,2.47,10,0.2,0.202,-0.5,1.73,-1.73,0.19,0,0,-1.9,0.6
ENSMUSG00000069722,KRTAP3-3,keratin associated protein 3-3,cellular_component|,biological_process|,molecular_function|,10,0.2,0.85,10,0.3,1.06,0.2,1.73,1.73,0.19,0,0,-1.5,1.2
ENSMUSG00000045725,PRR15,proline rich 15,cellular_component|,multicellular organismal development|biological_process|,molecular_function|,10,0.1,0.186,10,0.7,2.03,0.2,1.73,1.73,0.19,0,0,-0.6,1.9
ENSMUSG00000021260,HHIPL1,hedgehog interacting protein-like 1,extracellular region|membrane|,carbohydrate metabolic process|biological_process|,"catalytic activity|scavenger receptor activity|oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor|quinone binding|",10,0.3,1.57,10,0.2,0.423,0.2,1.73,1.73,0.19,0,0,-0.7,1.6
ENSMUSG00000023992,TREM2,triggering receptor expressed on myeloid cells 2,extracellular region|plasma membrane|membrane|integral component of membrane|,positive regulation of antigen processing and presentation of peptide antigen via MHC class II|signal transduction|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of calcium-mediated signaling|positive regulation of ERK1 and ERK2 cascade|dendritic cell differentiation|positive regulation of protein localization to plasma membrane|positive regulation of C-C chemokine receptor CCR7 signaling pathway|positive regulation of CD40 signaling pathway|,lipopolysaccharide binding|transmembrane signaling receptor activity|protein binding|scaffold protein binding|,10,0.3,2.07,10,0.1,0.152,0.2,1.73,1.73,0.19,0,0,-0.9,1.7
ENSMUSG00000069721,KRTAP3-2,keratin associated protein 3-2,cellular_component|,biological_process|,molecular_function|,10,0.2,0.85,10,0.3,1.06,0.2,1.73,1.73,0.19,0,0,-1.5,1.2
ENSMUSG00000070509,RGMA,repulsive guidance molecule family member A,endoplasmic reticulum|plasma membrane|cell surface|membrane|anchored component of membrane|extracellular vesicular exosome|,neural tube closure|positive regulation of protein phosphorylation|BMP signaling pathway|regulation of BMP signaling pathway|regulation of BMP signaling pathway|regulation of BMP signaling pathway|,protein binding|coreceptor activity|,10,0.9,3.84,10,-0.4,0.336,0.2,1.71,1.71,0.193,0,0,-0.6,2
ENSMUSG00000030518,FAM189A1,"family with sequence similarity 189, member A1",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-1.5,4.95,-1.5,1.71,-1.71,0.193,0,0,-3,0.1
ENSMUSG00000090515,KRTAP27-1,keratin associated protein 27-1,cellular_component|,biological_process|,molecular_function|,10,-0.2,2.16,10,0,0,-0.2,1.7,-1.7,0.194,0,0,-1.6,0.9
ENSMUSG00000050050,CCDC158,coiled-coil domain containing 158,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.61,10,-0.1,0.263,-0.2,1.7,-1.7,0.194,0,0,-1.5,1.2
ENSMUSG00000027460,ANGPT4,angiopoietin 4,extracellular region|extracellular space|,angiogenesis|activation of transmembrane receptor protein tyrosine kinase activity|endoderm development|positive regulation of endothelial cell migration|negative regulation of angiogenesis|negative regulation of apoptotic process|positive regulation of blood vessel endothelial cell migration|negative regulation of blood vessel endothelial cell migration|positive regulation of angiogenesis|Tie signaling pathway|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of protein tyrosine kinase activity|positive regulation of receptor activity|,vascular endothelial growth factor receptor binding|transmembrane receptor protein tyrosine kinase activator activity|receptor tyrosine kinase binding|,10,-0.2,1.6,10,-0.2,0.211,-0.2,1.69,-1.69,0.195,0,0,-1.7,0.7
ENSMUSG00000089798,1700028K03RIK,RIKEN cDNA 1700028K03 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,0.699,10,-0.6,1.47,-0.6,1.68,-1.68,0.196,0,0,-1.8,0.7
ENSMUSG00000027219,SLC28A2,"solute carrier family 28 (sodium-coupled nucleoside transporter), member 2",integral component of plasma membrane|membrane|integral component of membrane|,retina homeostasis|transport|purine nucleoside transmembrane transport|purine nucleoside transmembrane transport|protein localization to cell surface|sodium ion transmembrane transport|nucleoside transmembrane transport|,nucleoside binding|nucleoside transmembrane transporter activity|nucleoside:sodium symporter activity|purine nucleoside transmembrane transporter activity|,10,0.8,1.12,10,-0.3,1.37,-0.3,1.67,-1.67,0.197,0,0,-1.5,1.6
ENSMUSG00000058014,OLFR502,olfactory receptor 502,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1,4.6,10,0.2,1.54,-0.9,1.66,-1.66,0.198,0,0,-2,0.9
ENSMUSG00000032343,IMPG1,interphotoreceptor matrix proteoglycan 1,extracellular region|,None,None,10,-0.4,1.85,10,-0.1,0.0965,-0.2,1.66,-1.66,0.198,0,0,-1.7,0.6
ENSMUSG00000031722,HP,haptoglobin,extracellular region|extracellular space|endoplasmic reticulum|Golgi apparatus|haptoglobin-hemoglobin complex|extracellular vesicular exosome|blood microparticle|,liver development|immune system process|proteolysis|acute-phase response|positive regulation of cell death|response to hydrogen peroxide|defense response to bacterium|negative regulation of oxidoreductase activity|negative regulation of hydrogen peroxide catabolic process|,catalytic activity|serine-type endopeptidase activity|antioxidant activity|hemoglobin binding|protein homodimerization activity|,10,-0.2,1.14,10,-0.2,0.655,-0.2,1.66,-1.66,0.198,0,0,-1.6,0.7
ENSMUSG00000089722,GM11711,predicted gene 11711,cellular_component|,biological_process|,molecular_function|,10,0.2,0.484,10,0.4,1.53,0.2,1.65,1.65,0.2,0,0,-0.5,1.8
ENSMUSG00000036855,GJD4,"gap junction protein, delta 4",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,cell communication|regulation of satellite cell activation involved in skeletal muscle regeneration|,molecular_function|,10,-0.5,2.66,10,0.1,0.435,-0.5,1.65,-1.65,0.2,0,0,-1.8,0.5
ENSMUSG00000069609,GM11710,predicted gene 11710,cellular_component|,biological_process|,molecular_function|,10,0.2,0.484,10,0.4,1.53,0.2,1.65,1.65,0.2,0,0,-0.5,1.8
ENSMUSG00000046474,KRTAP4-16,keratin associated protein 4-16,cellular_component|intermediate filament|,aging|hair cycle|,molecular_function|,10,-0.2,0.616,10,-0.3,1.17,-0.2,1.65,-1.65,0.2,0,0,-1.6,0.8
ENSMUSG00000067144,SLC22A7,"solute carrier family 22 (organic anion transporter), member 7",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|organic anion transport|organic anion transport|organic anion transport|ion transmembrane transport|transmembrane transport|,organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|ion transmembrane transporter activity|transmembrane transporter activity|,10,-0.4,1.41,10,-0.3,0.417,-0.3,1.64,-1.64,0.201,0,0,-1.7,0.7
ENSMUSG00000057447,OLFR1205,olfactory receptor 1205,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,1.86,10,0.1,0.22,0.2,1.64,1.64,0.201,0,0,-1.7,1.1
ENSMUSG00000039335,SPATA16,spermatogenesis associated 16,Golgi apparatus|cytoplasmic vesicle|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,0.3,1.02,10,-0.7,2.96,0.3,1.64,1.64,0.201,0,0,-1.6,1.4
ENSMUSG00000041695,KCNJ2,"potassium inwardly-rectifying channel, subfamily J, member 2",smooth endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|plasma membrane|voltage-gated potassium channel complex|intercalated disc|membrane|integral component of membrane|T-tubule|dendrite|intrinsic component of membrane|neuronal cell body|dendritic spine|,transport|ion transport|potassium ion transport|potassium ion import|regulation of skeletal muscle contraction via regulation of action potential|magnesium ion transport|regulation of ion transmembrane transport|protein homotetramerization|relaxation of cardiac muscle|regulation of membrane repolarization|potassium ion transmembrane transport|cardiac muscle cell action potential|cardiac muscle cell action potential involved in contraction|regulation of cardiac muscle cell contraction|membrane repolarization during action potential|membrane repolarization during cardiac muscle cell action potential|regulation of heart rate by cardiac conduction|relaxation of skeletal muscle|positive regulation of potassium ion transmembrane transport|,"inward rectifier potassium channel activity|voltage-gated ion channel activity|protein binding|phosphatidylinositol-4,5-bisphosphate binding|identical protein binding|voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization|",10,0.3,1.4,10,0.3,0.369,0.3,1.64,1.64,0.201,0,0,-0.6,1.7
ENSMUSG00000001123,LGALS9,"lectin, galactose binding, soluble 9",extracellular region|cytoplasm|,heterophilic cell-cell adhesion|,galactoside binding|carbohydrate binding|,9,-0.6,2.87,9,0,0,-0.5,1.63,-1.63,0.202,0,0,-1.9,0.5
ENSMUSG00000071471,KRTAP26-1,keratin associated protein 26-1,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.3,2.42,10,0.1,0.0132,0.2,1.63,1.63,0.202,0,0,-0.9,1.5
ENSMUSG00000045792,OLFR578,olfactory receptor 578,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.57,10,0.1,0.29,0.3,1.63,1.63,0.202,0,0,-1,1.7
ENSMUSG00000071862,LRRTM2,leucine rich repeat transmembrane neuronal 2,plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|excitatory synapse|,negative regulation of receptor internalization|synapse organization|synapse organization|long-term synaptic potentiation|,neurexin family protein binding|,10,0.6,0.925,10,-1.4,1.94,-1.2,1.63,-1.63,0.202,0,0,-3,0.8
ENSMUSG00000036921,4930549C01RIK,RIKEN cDNA 4930549C01 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,2.19,-0.3,1.62,-1.62,0.204,0,0,-1.6,0.6
ENSMUSG00000032523,HHATL,hedgehog acyltransferase-like,endoplasmic reticulum|membrane|integral component of membrane|perinuclear region of cytoplasm|,negative regulation of N-terminal protein palmitoylation|,protein binding|,10,-0.3,2.09,10,0,0,-0.3,1.62,-1.62,0.204,0,0,-1.7,0.5
ENSMUSG00000047735,SAMD9L,sterile alpha motif domain containing 9-like,early endosome|,hematopoietic progenitor cell differentiation|stem cell division|endosomal vesicle fusion|common myeloid progenitor cell proliferation|regulation of protein catabolic process|spleen development|,molecular_function|,10,-0.1,0.342,10,-1,2.43,-0.3,1.62,-1.62,0.204,0,0,-2,1.1
ENSMUSG00000074595,WFDC6A,WAP four-disulfide core domain 6A,cellular_component|extracellular region|,negative regulation of peptidase activity|defense response to bacterium|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.4,1.77,10,0.2,0.543,-0.4,1.62,-1.62,0.204,0,0,-1.3,1.4
ENSMUSG00000039116,GPR126,G protein-coupled receptor 126,cytoplasm|plasma membrane|cell surface|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,-0.1,0.173,10,1.1,4.6,0.2,1.62,1.62,0.204,0,0,-1,2
ENSMUSG00000045655,FAM216B,"family with sequence similarity 216, member B",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.655,10,-0.7,1.77,-0.2,1.61,-1.61,0.205,0,0,-1.9,0.3
ENSMUSG00000039883,LRRC17,leucine rich repeat containing 17,extracellular region|extracellular space|,ossification|negative regulation of osteoclast differentiation|bone marrow development|,molecular_function|,10,0.3,2.71,10,-0.2,0.444,0.2,1.6,1.6,0.206,0,0,-1.2,1.4
ENSMUSG00000050613,OLFR125,olfactory receptor 125,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,2.91,10,0,0,-0.3,1.6,-1.6,0.206,0,0,-1.8,0.6
ENSMUSG00000059763,TAAR2,trace amine-associated receptor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,trace-amine receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|,10,0,0,10,0.5,3.85,0.4,1.6,1.6,0.206,0,0,-0.8,1.7
ENSMUSG00000040154,WFDC5,WAP four-disulfide core domain 5,cellular_component|,biological_process|,molecular_function|,10,-0.6,3.9,10,0,0,-0.5,1.59,-1.59,0.207,0,0,-1.9,0.3
ENSMUSG00000071340,TRAPPC3L,trafficking protein particle complex 3 like,cellular_component|endoplasmic reticulum|Golgi apparatus|,transport|biological_process|vesicle-mediated transport|,molecular_function|,10,0.7,3.89,10,0.1,0.0207,0.7,1.59,1.59,0.207,0,0,-1,1.9
ENSMUSG00000096481,GM3250,predicted gene 3250,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.4,1.78,10,-1.1,3.49,0.4,1.59,1.59,0.207,0,0,-2,0.9
ENSMUSG00000038576,SUSD4,sushi domain containing 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-1.5,4.91,10,0.2,1,-1.5,1.59,-1.59,0.207,0,0,-3,0.4
ENSMUSG00000038201,KCNA7,"potassium voltage-gated channel, shaker-related subfamily, member 7",voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.2,1.82,10,0.1,0.0484,0.2,1.59,1.59,0.207,0,0,-1.2,1.4
ENSMUSG00000050315,SYNPO2,synaptopodin 2,nucleus|nucleus|cytoplasm|actin cytoskeleton|Z disc|Z disc|,None,actin binding|protein binding|muscle alpha-actinin binding|14-3-3 protein binding|,10,-0.3,1.45,10,-0.2,0.301,-0.2,1.58,-1.58,0.209,0,0,-1.7,0.8
ENSMUSG00000075158,OLFR1111,olfactory receptor 1111,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.311,10,-0.5,1.6,-0.2,1.58,-1.58,0.209,0,0,-1.8,0.7
ENSMUSG00000073380,ARRDC5,arrestin domain containing 5,cellular_component|,signal transduction|biological_process|,molecular_function|,10,0.2,1.05,10,-0.3,1.58,0.2,1.58,1.58,0.209,0,0,-1.2,1.4
ENSMUSG00000064333,OLFR926,olfactory receptor 926,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.99,10,0.1,0.873,0.2,1.58,1.58,0.209,0,0,-1.5,1.3
ENSMUSG00000040972,IGSF21,"immunoglobulin superfamily, member 21",cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.3,0.943,10,-0.5,0.952,-0.3,1.58,-1.58,0.209,0,0,-1.7,0.7
ENSMUSG00000056350,KRTAP13-1,keratin associated protein 13-1,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,1.6,2.4,10,-0.2,0.982,-0.2,1.57,-1.57,0.21,0,0,-1.3,2.8
ENSMUSG00000089942,PIRA2,paired-Ig-like receptor A2,cellular_component|,biological_process|,molecular_function|,10,-0.4,2.41,10,-0.1,0.113,-0.4,1.57,-1.57,0.21,0,0,-1.9,0.6
ENSMUSG00000069607,CD300LH,CD300 antigen like family member H,lysosome|endosome|plasma membrane|membrane|integral component of membrane|,immune system process|positive regulation of protein ubiquitination|positive regulation of toll-like receptor 9 signaling pathway|positive regulation of toll-like receptor 9 signaling pathway|,protein binding|,10,0.2,0.392,10,0.4,1.53,0.2,1.56,1.56,0.212,0,0,-0.5,1.8
ENSMUSG00000028492,FAM154A,"family with sequence similarity 154, member A",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.167,10,-0.3,1.64,-0.2,1.56,-1.56,0.212,0,0,-1.5,1
ENSMUSG00000024670,CD6,CD6 antigen,plasma membrane|membrane|integral component of membrane|fully spanning plasma membrane|,positive regulation of protein phosphorylation|cell adhesion|,glycoprotein binding|scavenger receptor activity|protein binding|protein kinase binding|,10,-0.3,0.186,10,-0.3,1.47,-0.3,1.55,-1.55,0.213,0,0,-1.7,0.5
ENSMUSG00000072707,OLFR31,olfactory receptor 31,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,2.27,10,0.4,3.25,0.3,1.54,1.54,0.214,0,0,-1.1,1.4
ENSMUSG00000000159,IGSF5,"immunoglobulin superfamily, member 5",plasma membrane|tight junction|cell surface|membrane|integral component of membrane|cell junction|,single organismal cell-cell adhesion|,protein binding|PDZ domain binding|,10,-0.4,2.71,10,0.6,3.46,0.6,1.53,1.53,0.216,0,0,-1.2,1.6
ENSMUSG00000030049,GKN2,gastrokine 2,cellular_component|extracellular region|Golgi apparatus|,biological_process|,molecular_function|,10,0.2,0.401,10,0.3,1.5,0.3,1.53,1.53,0.216,0,0,-0.9,1.6
ENSMUSG00000048108,TMEM72,transmembrane protein 72,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,0.816,10,0.2,0.889,0.3,1.53,1.53,0.216,0,0,-0.7,1.6
ENSMUSG00000063116,OLFR410,olfactory receptor 410,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,1.37,10,0.2,0.279,0.2,1.53,1.53,0.216,0,0,-0.7,1.7
ENSMUSG00000049001,NDNF,neuron-derived neurotrophic factor,extracellular region|extracellular matrix|,neuron migration|nervous system development|positive regulation of cell-substrate adhesion|positive regulation of neuron projection development|cell growth|peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|extracellular matrix organization|negative regulation of neuron apoptotic process|,glycosaminoglycan binding|heparin binding|,10,-0.3,2.8,10,0.1,0.138,-0.3,1.53,-1.53,0.216,0,0,-1.6,0.8
ENSMUSG00000025082,VWA2,von Willebrand factor A domain containing 2,extracellular region|basement membrane|extracellular space|extracellular space|extracellular vesicular exosome|,calcium-independent cell-matrix adhesion|calcium-independent cell-matrix adhesion|regulation of insulin receptor signaling pathway|protein homooligomerization|protein homooligomerization|,identical protein binding|identical protein binding|,10,0.3,1.21,10,0.2,0.518,0.3,1.53,1.53,0.216,0,0,-0.9,1.5
ENSMUSG00000022860,CHODL,chondrolectin,cytoplasm|membrane|integral component of membrane|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,biological_process|,carbohydrate binding|,10,0.3,2.73,10,0,0,0.2,1.52,1.52,0.217,0,0,-0.9,1.5
ENSMUSG00000032243,ITGA11,integrin alpha 11,focal adhesion|integrin complex|membrane|integral component of membrane|,osteoblast differentiation|substrate-dependent cell migration|substrate-dependent cell migration|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|cell adhesion mediated by integrin|collagen-activated signaling pathway|,collagen binding|collagen receptor activity|metal ion binding|,10,-0.4,0.976,10,-0.2,0.875,-0.3,1.52,-1.52,0.217,0,0,-1.9,0.4
ENSMUSG00000058897,COL25A1,"collagen, type XXV, alpha 1",extracellular region|collagen trimer|extracellular space|integral component of plasma membrane|membrane|integral component of membrane|,biological_process|,beta-amyloid binding|heparin binding|,9,-0.2,0.397,9,-1,2.72,-0.3,1.52,-1.52,0.217,0,0,-2,0.8
ENSMUSG00000075370,IGLL1,immunoglobulin lambda-like polypeptide 1,extracellular region|extracellular vesicular exosome|,None,protein binding|,10,0.4,1.74,10,0.1,0.124,0.4,1.52,1.52,0.217,0,0,-0.4,1.8
ENSMUSG00000032377,PLSCR4,phospholipid scramblase 4,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,enzyme binding|CD4 receptor binding|,10,-0.2,1.07,10,0.5,1.3,0.3,1.52,1.52,0.217,0,0,-1.1,1.5
ENSMUSG00000034709,PPP1R21,"protein phosphatase 1, regulatory subunit 21",membrane|,biological_process|,phosphatase binding|,10,0.4,2.02,10,0.1,0.013,0.3,1.5,1.5,0.22,0,0,-1,1.8
ENSMUSG00000040690,COL16A1,"collagen, type XVI, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|,cell adhesion|cellular response to amino acid stimulus|,integrin binding|,10,0,0,10,-0.4,3.14,-0.3,1.49,-1.49,0.221,0,0,-1.7,0.6
ENSMUSG00000061947,SERPINA10,"serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10",extracellular region|extracellular space|,blood coagulation|hemostasis|negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|heparin binding|peptidase inhibitor activity|,10,0.1,0.175,10,-0.6,4.15,-0.6,1.49,-1.49,0.221,0,0,-1.9,0.7
ENSMUSG00000078255,KRTAP9-5,keratin associated protein 9-5,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.5,2.3,10,-0.1,0.166,-0.3,1.49,-1.49,0.221,0,0,-1.6,0.7
ENSMUSG00000059862,OLFR826,olfactory receptor 826,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,1.35,10,0.2,0.756,-0.2,1.49,-1.49,0.221,0,0,-1.6,1
ENSMUSG00000029306,IBSP,integrin binding sialoprotein,extracellular region|extracellular space|membrane|membrane-bounded vesicle|,ossification|osteoblast differentiation|cell adhesion|extracellular matrix organization|biomineral tissue development|cellular response to growth factor stimulus|,None,10,-0.5,2.31,10,0,0,-0.2,1.49,-1.49,0.221,0,0,-1.8,0.5
ENSMUSG00000086022,RAD51AP2,RAD51 associated protein 2,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.36,10,-0.2,0.38,-0.3,1.48,-1.48,0.223,0,0,-1.8,0.6
ENSMUSG00000047867,GIMAP6,"GTPase, IMAP family member 6",cytoplasm|cytosol|,biological_process|,nucleotide binding|molecular_function|GTP binding|,10,0.2,1.59,10,0,0,0.3,1.47,1.47,0.224,0,0,-1.2,1.4
ENSMUSG00000053217,TAS2R136,"taste receptor, type 2, member 136",membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|bitter taste receptor activity|,10,-0.4,2.35,10,0,0,-0.3,1.47,-1.47,0.224,0,0,-1.5,1.2
ENSMUSG00000062154,TEX33,testis expressed 33,cellular_component|,biological_process|,molecular_function|,10,0.3,2.46,10,0,0,0.2,1.46,1.46,0.226,0,0,-0.8,1.8
ENSMUSG00000027574,NKAIN4,Na+/K+ transporting ATPase interacting 4,plasma membrane|membrane|integral component of membrane|,None,None,10,0,0,10,-0.4,3.04,-0.3,1.46,-1.46,0.226,0,0,-1.8,0.5
ENSMUSG00000063350,OLFR874,olfactory receptor 874,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.531,10,-0.6,1.67,-0.5,1.45,-1.45,0.227,0,0,-1.8,0.5
ENSMUSG00000036699,ZCCHC12,"zinc finger, CCHC domain containing 12",nucleus|nuclear speck|,"transcription, DNA-templated|regulation of transcription, DNA-templated|BMP signaling pathway|positive regulation of ligand-dependent nuclear receptor transcription coactivator activity|",nucleic acid binding|protein binding|zinc ion binding|ligand-dependent nuclear receptor transcription coactivator activity|SUMO binding|metal ion binding|,10,0.1,0.055,10,-0.8,4.34,-0.7,1.45,-1.45,0.227,0,0,-2,0.3
ENSMUSG00000029158,YIPF7,"Yip1 domain family, member 7",endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.984,10,0.5,1.03,0.3,1.45,1.45,0.227,0,0,-1.5,1.3
ENSMUSG00000026343,GPR39,G protein-coupled receptor 39,cellular_component|plasma membrane|membrane|integral component of membrane|,diet induced thermogenesis|signal transduction|G-protein coupled receptor signaling pathway|adult feeding behavior|regulation of lipid metabolic process|positive regulation of insulin secretion|gastric emptying|positive regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of membrane potential|regulation of membrane potential|glucose homeostasis|cholesterol homeostasis|positive regulation of release of sequestered calcium ion into cytosol|negative regulation of gastric acid secretion|cellular response to zinc ion|,molecular_function|signal transducer activity|G-protein coupled receptor activity|metal ion binding|,10,-0.4,1.96,10,-1.2,1.54,-0.4,1.44,-1.44,0.229,0,0,-2,0.6
ENSMUSG00000046491,C1QTNF2,C1q and tumor necrosis factor related protein 2,extracellular region|collagen trimer|extracellular space|,activation of MAPK activity|positive regulation of glycogen biosynthetic process|positive regulation of fatty acid oxidation|positive regulation of glucose import|protein homooligomerization|protein trimerization|protein heterotrimerization|,receptor binding|identical protein binding|,10,0.4,3.49,10,-0.2,0.171,0.3,1.44,1.44,0.229,0,0,-0.9,1.8
ENSMUSG00000062082,CD200R4,CD200 receptor 4,external side of plasma membrane|membrane|integral component of membrane|,None,receptor activity|protein binding|,10,0.4,3.08,10,-0.9,3.81,-0.3,1.43,-1.43,0.23,0,0,-2,0.9
ENSMUSG00000092519,ACTL9,actin-like 9,cellular_component|cytoplasm|cytoskeleton|,biological_process|,molecular_function|,10,0.2,1.51,10,0.1,0.178,0.2,1.43,1.43,0.23,0,0,-1.2,1.4
ENSMUSG00000043085,TMEM82,transmembrane protein 82,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.7,4.13,10,0.2,0.805,-0.6,1.43,-1.43,0.23,0,0,-1.9,0.8
ENSMUSG00000042581,THSD7B,"thrombospondin, type I, domain containing 7B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.7,4.32,0.7,1.42,1.42,0.231,0,0,-0.3,1.9
ENSMUSG00000062564,TEX28,testis expressed 28,cellular_component|,biological_process|,molecular_function|,10,0.2,1.21,9,0.2,0.319,0.2,1.42,1.42,0.231,0,0,-1.2,1.5
ENSMUSG00000022518,4930562C15RIK,RIKEN cDNA 4930562C15 gene,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.5,10,-0.2,0.128,-0.4,1.41,-1.41,0.233,0,0,-1.8,0.7
ENSMUSG00000045479,OLFR459,olfactory receptor 459,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.4,2.67,-0.4,1.41,-1.41,0.233,0,0,-1.7,0.6
ENSMUSG00000022270,FAM134B,"family with sequence similarity 134, member B",Golgi apparatus|cis-Golgi network|membrane|integral component of membrane|,sensory perception of pain|,molecular_function|,10,0.4,2.32,10,0,0,0.3,1.41,1.41,0.233,0,0,-0.9,1.7
ENSMUSG00000049130,C5AR1,complement component 5a receptor 1,plasma membrane|cell surface|membrane|integral component of membrane|basolateral plasma membrane|apical part of cell|,complement receptor mediated signaling pathway|apoptotic process|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|cell proliferation in hindbrain|neutrophil chemotaxis|response to peptidoglycan|complement component C5a signaling pathway|mRNA transcription from RNA polymerase II promoter|negative regulation of neuron apoptotic process|positive regulation of epithelial cell proliferation|defense response to Gram-positive bacterium|positive regulation of ERK1 and ERK2 cascade|,complement component C5a binding|signal transducer activity|complement component C5a receptor activity|G-protein coupled receptor activity|C5a anaphylatoxin receptor activity|C5a anaphylatoxin receptor activity|,10,0.3,1.61,10,0.1,0.197,0.2,1.41,1.41,0.233,0,0,-1,1.6
ENSMUSG00000036231,AGR3,anterior gradient 3,cellular_component|extracellular region|,biological_process|,dystroglycan binding|,10,0,0,10,-0.5,3.53,-0.4,1.41,-1.41,0.233,0,0,-1.7,0.7
ENSMUSG00000021396,NXNL2,nucleoredoxin-like 2,cellular_component|,visual perception|sensory perception of smell|,molecular_function|,10,-0.3,0.451,10,-0.3,1.07,-0.3,1.41,-1.41,0.233,0,0,-1.8,0.5
ENSMUSG00000040770,IL25,interleukin 25,None,inflammatory response to antigenic stimulus|inflammatory response|inflammatory response|inflammatory response|response to fungus|response to nematode|eosinophil differentiation|positive regulation of transcription from RNA polymerase II promoter|,cytokine activity|interleukin-17E receptor binding|,10,0,0,10,1.2,4.34,1.2,1.41,1.41,0.233,0,0,-0.3,2
ENSMUSG00000049598,VSIG8,V-set and immunoglobulin domain containing 8,intracellular|membrane|integral component of membrane|,biological_process|,poly(A) RNA binding|,10,0.6,3.48,10,0,0,0.5,1.41,1.41,0.233,0,0,-0.5,1.9
ENSMUSG00000095817,GM3238,predicted gene 3238,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.3,1.2,10,-0.3,0.842,0.2,1.41,1.41,0.233,0,0,-1,1.7
ENSMUSG00000058084,OLFR825,olfactory receptor 825,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0678,10,-0.6,2.33,-0.2,1.4,-1.4,0.235,0,0,-1.9,0.7
ENSMUSG00000052316,LRRC15,leucine rich repeat containing 15,intracellular|membrane|integral component of membrane|extracellular vesicular exosome|,positive regulation of cell migration|receptor-mediated virion attachment to host cell|negative regulation of establishment of protein localization to plasma membrane|,fibronectin binding|collagen binding|laminin binding|,10,0.4,2.16,10,-0.5,0.72,0.3,1.4,1.4,0.235,0,0,-1.1,1.7
ENSMUSG00000028753,VWA5B1,von Willebrand factor A domain containing 5B1,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.2,0.564,10,0.3,1.08,0.2,1.39,1.39,0.236,0,0,-1.4,1.4
ENSMUSG00000024330,COL11A2,"collagen, type XI, alpha 2",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type XI trimer|,skeletal system development|ossification|tissue homeostasis|chondrocyte differentiation|sensory perception of sound|sensory perception of sound|collagen fibril organization|collagen fibril organization|skeletal system morphogenesis|cartilage development|palate development|soft palate development|,extracellular matrix structural constituent|metal ion binding|,9,0.2,0.834,9,0.4,0.748,0.2,1.39,1.39,0.236,0,0,-1,1.7
ENSMUSG00000005364,IL5RA,"interleukin 5 receptor, alpha",membrane|integral component of membrane|,inflammatory response to antigenic stimulus|regulation of interleukin-5 production|cellular response to organic substance|,cytokine receptor activity|,10,0.4,3.42,10,0,0,0.3,1.39,1.39,0.236,0,0,-0.9,1.6
ENSMUSG00000063681,CRB1,crumbs homolog 1 (Drosophila),plasma membrane|microvillus|membrane|integral component of membrane|,plasma membrane organization|eye photoreceptor cell development|membrane organization|,calcium ion binding|protein binding|,10,-0.3,0.939,10,-0.3,0.57,-0.3,1.39,-1.39,0.236,0,0,-1.6,0.9
ENSMUSG00000018341,IL12RB2,"interleukin 12 receptor, beta 2",external side of plasma membrane|membrane|integral component of membrane|,peptidyl-tyrosine phosphorylation|response to lipopolysaccharide|interferon-gamma production|positive regulation of interferon-gamma production|response to cytokine|,cytokine receptor activity|protein binding|protein kinase binding|,10,0.1,0.333,10,0.2,1.29,0.2,1.38,1.38,0.238,0,0,-1,1.6
ENSMUSG00000040253,GBP7,guanylate binding protein 7,symbiont-containing vacuole membrane|cytoplasmic vesicle|,defense response to protozoan|defense response to protozoan|adhesion of symbiont to host|defense response to Gram-positive bacterium|cellular response to interferon-gamma|,molecular_function|,10,-0.7,4.06,10,0.3,2.16,-0.6,1.38,-1.38,0.238,0,0,-1.9,0.8
ENSMUSG00000051985,IGFN1,immunoglobulin-like and fibronectin type III domain containing 1,nucleus|cytoplasm|Z disc|,biological_process|,molecular_function|,10,-0.3,1.35,10,-0.1,0.265,-0.3,1.38,-1.38,0.238,0,0,-1.6,0.9
ENSMUSG00000051076,VTCN1,V-set domain containing T cell activation inhibitor 1,cell|plasma membrane|external side of plasma membrane|membrane|anchored component of membrane|,response to protozoan|immune system process|positive regulation of T cell proliferation|negative regulation of T cell activation|interleukin-4 secretion|interferon-gamma secretion|positive regulation of interleukin-2 secretion|,receptor binding|receptor binding|,10,-0.4,2.76,10,0,0,-0.3,1.38,-1.38,0.238,0,0,-1.4,1.1
ENSMUSG00000041669,PRIMA1,proline rich membrane anchor 1,plasma membrane|membrane|integral component of membrane|cell junction|intrinsic component of plasma membrane|synapse|,neurotransmitter catabolic process|establishment of localization in cell|,protein binding|enzyme binding|protein anchor|,10,0.1,0.251,10,-0.4,2.79,-0.4,1.38,-1.38,0.238,0,0,-1.7,0.7
ENSMUSG00000048521,CXCR6,chemokine (C-X-C motif) receptor 6,plasma membrane|membrane|integral component of membrane|,chemotaxis|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|coreceptor activity|C-X-C chemokine receptor activity|,10,-0.2,0.385,10,-0.5,1.34,-0.4,1.38,-1.38,0.238,0,0,-1.8,0.6
ENSMUSG00000074452,PATE2,prostate and testis expressed 2,extracellular region|extracellular space|,biological_process|,molecular_function|,10,0.1,0.378,10,0.3,1.26,0.2,1.38,1.38,0.238,0,0,-1,1.7
ENSMUSG00000059832,KPRP,"keratinocyte expressed, proline-rich",cytoplasm|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.2,0.83,10,-0.5,0.828,-0.4,1.37,-1.37,0.239,0,0,-1.7,0.9
ENSMUSG00000095377,OLFR91,olfactory receptor 91,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.8,3.55,-0.3,1.37,-1.37,0.239,0,0,-2,0.2
ENSMUSG00000057615,LDOC1,"leucine zipper, down-regulated in cancer 1",cellular_component|nucleus|,biological_process|,molecular_function|,10,0,0,10,0.8,3.34,0.2,1.37,1.37,0.239,0,0,-0.2,2
ENSMUSG00000012428,STEAP4,STEAP family member 4,endosome|Golgi apparatus|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|copper ion import|iron ion homeostasis|oxidation-reduction process|ferric iron import into cell|,cupric reductase activity|oxidoreductase activity|metal ion binding|ferric-chelate reductase (NADPH) activity|,10,0.3,1.39,10,0.1,0.214,0.3,1.36,1.36,0.241,0,0,-1.2,1.6
ENSMUSG00000073413,LY6G6D,"lymphocyte antigen 6 complex, locus G6D",cellular_component|plasma membrane|membrane|anchored component of membrane|cell projection|,biological_process|,molecular_function|,10,-0.3,2.8,10,0.1,0.24,-0.2,1.36,-1.36,0.241,0,0,-1.4,1.4
ENSMUSG00000023387,KCNK16,"potassium channel, subfamily K, member 16",cellular_component|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|potassium ion transmembrane transport|,potassium channel activity|,10,0.4,0.746,10,0.3,0.717,0.3,1.34,1.34,0.244,0,0,-1.1,1.5
ENSMUSG00000031518,SPATA4,spermatogenesis associated 4,cytoplasm|,biological_process|,protein binding|,10,-0.2,0.677,10,0.3,1.57,0.2,1.34,1.34,0.244,0,0,-1.3,1.3
ENSMUSG00000038704,ASPDH,aspartate dehydrogenase domain containing,cellular_component|,NADP catabolic process|NAD biosynthetic process|pyridine nucleotide biosynthetic process|oxidation-reduction process|,oxidoreductase activity|aspartate dehydrogenase activity|NADP binding|,10,0.3,1.26,10,0.5,0.251,0.3,1.34,1.34,0.244,0,0,-0.4,1.8
ENSMUSG00000034648,LRRN1,"leucine rich repeat protein 1, neuronal",membrane|integral component of membrane|,None,None,10,0.3,2.26,10,-0.3,1.47,0.2,1.34,1.34,0.244,0,0,-1.3,1.2
ENSMUSG00000063409,LRRC43,leucine rich repeat containing 43,cellular_component|,biological_process|,molecular_function|,10,0.5,1.46,10,-0.1,0.218,-0.2,1.34,-1.34,0.244,0,0,-1.6,1.3
ENSMUSG00000032105,PDZD3,PDZ domain containing 3,cytoplasm|endosome|brush border|brush border|membrane|subapical complex|apical part of cell|apical part of cell|,negative regulation of guanylate cyclase activity|,protein binding|protein C-terminus binding|guanylate cyclase inhibitor activity|,10,-0.1,0.0719,10,-0.7,2.87,-0.5,1.33,-1.33,0.246,0,0,-2,0.3
ENSMUSG00000047094,OFCC1,orofacial cleft 1 candidate 1,cytoplasm|endoplasmic reticulum|cytosol|microtubule cytoskeleton|perinuclear region of cytoplasm|,biological_process|,molecular_function|,10,1.4,1.35,10,0.3,1.53,0.2,1.31,1.31,0.25,0,0,-0.7,2.8
ENSMUSG00000058818,PIRB,paired Ig-like receptor B,plasma membrane|membrane|integral component of membrane|,B cell homeostasis|immune system process|cytokine-mediated signaling pathway|B cell mediated immunity|myeloid dendritic cell differentiation|,None,10,-1.2,3.27,10,-0.1,0.0546,-0.2,1.31,-1.31,0.25,0,0,-2,0.4
ENSMUSG00000021534,1700001L19RIK,RIKEN cDNA 1700001L19 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.639,10,-0.8,1.07,-0.2,1.31,-1.31,0.25,0,0,-2,0.4
ENSMUSG00000046486,OLFR231,olfactory receptor 231,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.5,1.98,10,0.1,0.44,0.3,1.3,1.3,0.251,0,0,-0.8,1.8
ENSMUSG00000075094,OLFR1230,olfactory receptor 1230,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,-0.3,1.54,9,0.1,0.131,-0.3,1.3,-1.3,0.251,0,0,-1.7,0.9
ENSMUSG00000078721,GM12429,predicted gene 12429,None,None,None,10,0.2,0.542,10,0.3,0.96,0.2,1.29,1.29,0.253,0,0,-0.7,1.8
ENSMUSG00000091017,FAM71A,"family with sequence similarity 71, member A",nucleus|,biological_process|,molecular_function|,10,-0.8,3.64,10,0,0,-0.6,1.29,-1.29,0.253,0,0,-2,0.2
ENSMUSG00000054666,OLFR63,olfactory receptor 63,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,0.1,0.122,10,0.5,1.69,0.2,1.29,1.29,0.253,0,0,-0.9,1.7
ENSMUSG00000059873,OLFR1029,olfactory receptor 1029,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,2.44,10,0,0,-0.2,1.28,-1.28,0.255,0,0,-1.8,0.7
ENSMUSG00000033768,NRXN2,neurexin II,cell|membrane|integral component of membrane|presynaptic membrane|,synaptic transmission|neurotransmitter secretion|synapse assembly|adult behavior|social behavior|vocal learning|vocalization behavior|,calcium channel regulator activity|protein binding|,10,0,0,10,0.3,2.06,0.2,1.28,1.28,0.255,0,0,-0.7,1.7
ENSMUSG00000036800,FAM135B,"family with sequence similarity 135, member B",cellular_component|,biological_process|,molecular_function|,10,-0.2,2.27,10,0,0,-0.2,1.27,-1.27,0.257,0,0,-1.9,0.5
ENSMUSG00000004730,EMR1,"EGF-like module containing, mucin-like, hormone receptor-like sequence 1",plasma membrane|external side of plasma membrane|membrane|integral component of membrane|cell periphery|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcium ion binding|,10,1.1,4.03,10,0,0,1,1.27,1.27,0.257,0,0,-0.2,2
ENSMUSG00000063130,CALML3,calmodulin-like 3,extracellular vesicular exosome|,biological_process|,calcium ion binding|metal ion binding|,10,-0.4,2.87,10,0,0,-0.3,1.27,-1.27,0.257,0,0,-1.7,0.8
ENSMUSG00000030976,TEX36,testis expressed 36,cellular_component|,biological_process|,molecular_function|,10,0.2,1.66,10,0,0,0.2,1.27,1.27,0.257,0,0,-1.2,1.5
ENSMUSG00000075200,OLFR1044,olfactory receptor 1044,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,1.43,10,0.2,0.241,-0.2,1.26,-1.26,0.258,0,0,-1.6,1
ENSMUSG00000079363,GBP4,guanylate binding protein 4,extracellular vesicular exosome|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of protein phosphorylation|negative regulation of protein ubiquitination|negative regulation of interferon-alpha production|negative regulation of protein import into nucleus|regulation of defense response to virus|cellular response to interferon-gamma|,protein binding|,10,0.2,1.22,10,0.1,0.158,0.2,1.26,1.26,0.258,0,0,-0.9,1.7
ENSMUSG00000033268,DUOX1,dual oxidase 1,plasma membrane|membrane|integral component of membrane|,cytokine-mediated signaling pathway|cuticle development|response to cAMP|oxidation-reduction process|reactive oxygen species metabolic process|,protein binding|oxidoreductase activity|,10,0.2,1.3,10,0.9,1.18,0.3,1.25,1.25,0.26,0,0,-0.5,2
ENSMUSG00000020589,FAM49A,"family with sequence similarity 49, member A",intracellular|,biological_process|,molecular_function|,10,-0.7,3.96,10,0,0,-0.7,1.25,-1.25,0.26,0,0,-1.7,1.7
ENSMUSG00000058222,OLFR318,olfactory receptor 318,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.126,10,0.8,2.04,0.7,1.24,1.24,0.262,0,0,-0.4,2
ENSMUSG00000025081,TDRD1,tudor domain containing 1,cytoplasm|ribonucleoprotein complex|chromatoid body|P granule|pi-body|,meiotic nuclear division|multicellular organismal development|germ cell development|spermatogenesis|cell differentiation|gene silencing by RNA|piRNA metabolic process|DNA methylation involved in gamete generation|,protein binding|metal ion binding|,10,0.2,1.45,10,-0.5,0.682,0.2,1.24,1.24,0.262,0,0,-1.7,1.1
ENSMUSG00000073954,OLFR594,olfactory receptor 594,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,1.14,10,0.5,0.253,0.2,1.24,1.24,0.262,0,0,-0.8,1.7
ENSMUSG00000021791,DYDC2,DPY30 domain containing 2,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.915,10,0.3,0.602,-0.2,1.23,-1.23,0.263,0,0,-1.4,1.2
ENSMUSG00000050645,DEFB19,defensin beta 19,cellular_component|extracellular region|,defense response|biological_process|defense response to bacterium|,molecular_function|,10,0.2,0.633,10,-0.2,1.77,-0.2,1.23,-1.23,0.263,0,0,-1.3,1.4
ENSMUSG00000071234,SYNDIG1L,synapse differentiation inducing 1 like,Golgi apparatus|membrane|integral component of membrane|,biological_process|response to biotic stimulus|,molecular_function|,10,-0.1,0.0611,10,0.3,1.98,0.2,1.23,1.23,0.263,0,0,-1.1,1.5
ENSMUSG00000056605,KRT72,keratin 72,intermediate filament|keratin filament|,None,structural molecule activity|,10,0.2,0.793,10,0.8,1.1,0.2,1.22,1.22,0.265,0,0,-0.4,1.9
ENSMUSG00000018412,KANSL1,KAT8 regulatory NSL complex subunit 1,histone acetyltransferase complex|nucleus|MLL1 complex|,chromatin modification|histone H4-K5 acetylation|histone H4-K8 acetylation|histone H4-K16 acetylation|,histone acetyltransferase activity (H4-K5 specific)|histone acetyltransferase activity (H4-K8 specific)|histone acetyltransferase activity (H4-K16 specific)|,9,-0.4,1.77,9,-0.1,0.114,-0.3,1.22,-1.22,0.265,0,0,-1.4,1.3
ENSMUSG00000032023,4931429I11RIK,RIKEN cDNA 4931429I11 gene,cellular_component|,brain development|ciliary basal body organization|cerebrospinal fluid secretion|axoneme assembly|,molecular_function|,10,-0.4,2.01,10,-0.1,0.0167,-0.2,1.21,-1.21,0.267,0,0,-1.7,0.7
ENSMUSG00000044647,CSRNP3,cysteine-serine-rich nuclear protein 3,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transcription from RNA polymerase II promoter|apoptotic process|negative regulation of phosphatase activity|positive regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|",RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|DNA binding|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding|,10,-0.3,1.59,10,0,0,-0.2,1.21,-1.21,0.267,0,0,-1.7,0.7
ENSMUSG00000078639,GM12695,predicted gene 12695,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.62,10,-0.1,0.14,-0.2,1.21,-1.21,0.267,0,0,-1.5,1.1
ENSMUSG00000041552,PTCHD1,patched domain containing 1,plasma membrane|membrane|integral component of membrane|,smoothened signaling pathway|cognition|,molecular_function|hedgehog receptor activity|,10,0.3,0.952,10,0.1,0.472,0.3,1.21,1.21,0.267,0,0,-0.9,1.6
ENSMUSG00000021719,RGS7BP,regulator of G-protein signalling 7 binding protein,nucleus|cytoplasm|plasma membrane|membrane|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|,protein binding|,10,0.8,2.92,10,0,0,0.1,1.2,1.2,0.269,0,0,-0.3,2
ENSMUSG00000042041,2010003K11RIK,RIKEN cDNA 2010003K11 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.538,10,0.2,0.759,0.2,1.19,1.19,0.27,0,0,-1.4,1.4
ENSMUSG00000025787,TGM4,transglutaminase 4 (prostate),extracellular region|cytoplasm|Golgi apparatus|extracellular matrix|extracellular vesicular exosome|,peptide cross-linking|mating plug formation|,"molecular_function|protein-glutamine gamma-glutamyltransferase activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,-0.3,2.08,10,0.6,0.724,-0.2,1.19,-1.19,0.27,0,0,-1.4,1.5
ENSMUSG00000033963,FANCD2OS,Fancd2 opposite strand,cellular_component|,biological_process|,molecular_function|,10,-0.9,1.16,10,0.7,1.82,0.2,1.19,1.19,0.27,0,0,-1.6,1.6
ENSMUSG00000043298,SMCO3,single-pass membrane protein with coiled-coil domains 3,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,2.19,10,-0.1,0.0876,0.2,1.19,1.19,0.27,0,0,-1.8,1.2
ENSMUSG00000094891,OLFR55,olfactory receptor 55,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,1.96,10,0,0,0.3,1.18,1.18,0.272,0,0,-0.5,1.8
ENSMUSG00000050830,VWC2,von Willebrand factor C domain containing 2,extracellular region|proteinaceous extracellular matrix|basement membrane|interstitial matrix|extracellular space|cell junction|extracellular matrix|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|,positive regulation of cell-substrate adhesion|negative regulation of BMP signaling pathway|positive regulation of neuron differentiation|,molecular_function|,10,-0.3,0.562,10,0.2,0.74,0.2,1.18,1.18,0.272,0,0,-1.6,1.3
ENSMUSG00000008874,CLEC3A,"C-type lectin domain family 3, member a",cellular_component|extracellular region|,biological_process|,carbohydrate binding|,10,0.2,0.805,10,0.3,0.706,0.2,1.18,1.18,0.272,0,0,-1.1,1.5
ENSMUSG00000091685,GM17359,"predicted gene, 17359",None,None,None,10,0.1,0.325,10,0.4,1.56,0.3,1.17,1.17,0.274,0,0,-1.6,1.4
ENSMUSG00000066756,IGFL3,IGF-like family member 3,extracellular region|extracellular space|,biological_process|,protein binding|,10,0.3,0.686,10,0.3,0.585,0.3,1.17,1.17,0.274,0,0,-0.6,1.8
ENSMUSG00000039115,ITGA9,integrin alpha 9,basal plasma membrane|membrane|integral component of membrane|integrin alpha9-beta1 complex|,cell adhesion|integrin-mediated signaling pathway|neutrophil chemotaxis|,collagen binding|laminin binding|,10,-0.3,1.25,10,-0.1,0.235,-0.2,1.17,-1.17,0.274,0,0,-1.7,0.8
ENSMUSG00000050439,ENTHD1,ENTH domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.989,10,0.6,0.35,-0.3,1.16,-1.16,0.276,0,0,-1.6,1.3
ENSMUSG00000043448,GJC2,"gap junction protein, gamma 2",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|myelin sheath|,cell communication|cell-cell signaling|response to toxic substance|transmembrane transport|,gap junction channel activity|,10,-0.1,0.373,10,-0.3,1.14,-0.2,1.15,-1.15,0.278,0,0,-1.8,0.6
ENSMUSG00000047969,OLFR1093,olfactory receptor 1093,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.9,1.53,10,0.2,0.708,0.5,1.15,1.15,0.278,0,0,-0.7,2
ENSMUSG00000039385,CDH6,cadherin 6,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|,calcium ion binding|metal ion binding|,8,-0.3,0.208,9,-1,2.32,-0.4,1.15,-1.15,0.278,0,0,-2,0.8
ENSMUSG00000054675,TMEM119,transmembrane protein 119,endoplasmic reticulum|membrane|integral component of membrane|,ossification|osteoblast differentiation|osteoblast differentiation|cell differentiation|,protein binding|,10,0.2,0.89,10,0.1,0.455,0.2,1.15,1.15,0.278,0,0,-1,1.6
ENSMUSG00000049011,OLFR729,olfactory receptor 729,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.504,10,-0.3,0.803,-0.2,1.15,-1.15,0.278,0,0,-1.7,0.8
ENSMUSG00000024502,JAKMIP2,janus kinase and microtubule interacting protein 2,cellular_component|,biological_process|,molecular_function|,10,-0.3,2.7,10,0.1,0.315,-0.2,1.15,-1.15,0.278,0,0,-1.6,1
ENSMUSG00000027270,LAMP5,"lysosomal-associated membrane protein family, member 5",endosome|plasma membrane|plasma membrane|endosome membrane|membrane|integral component of membrane|cytoplasmic vesicle membrane|cytoplasmic vesicle|early endosome membrane|growth cone membrane|dendrite membrane|endoplasmic reticulum-Golgi intermediate compartment membrane|cell projection|recycling endosome membrane|,biological_process|,molecular_function|,10,0.5,1.71,10,0.1,0.534,0.3,1.14,1.14,0.28,0,0,-0.8,1.7
ENSMUSG00000032110,ACRV1,acrosomal vesicle protein 1,acrosomal vesicle|,None,None,10,-0.3,0.66,10,0.3,1.45,0.3,1.13,1.13,0.282,0,0,-1.2,1.4
ENSMUSG00000022112,GPC5,glypican 5,extracellular region|proteinaceous extracellular matrix|plasma membrane|integral component of plasma membrane|membrane|anchored component of membrane|,None,heparan sulfate proteoglycan binding|,10,0.7,0.951,10,0.4,0.377,0.4,1.13,1.13,0.282,0,0,-1,1.8
ENSMUSG00000026124,CFC1,"cripto, FRL-1, cryptic family 1",extracellular region|plasma membrane|membrane|anchored component of membrane|,liver development|heart looping|heart morphogenesis|multicellular organismal development|determination of left/right symmetry|gastrulation|endoderm development|post-embryonic development|anterior/posterior pattern specification|BMP signaling pathway|nodal signaling pathway|spleen development|digestive tract morphogenesis|anatomical structure development|canonical Wnt signaling pathway|atrial septum morphogenesis|left lung morphogenesis|respiratory system development|,nodal binding|activin receptor binding|,10,0.2,0.848,10,0.2,0.383,0.2,1.13,1.13,0.282,0,0,-0.9,1.7
ENSMUSG00000094985,TOPAZ1,testis and ovary specific PAZ domain containing 1,cellular_component|cytoplasm|,biological_process|,molecular_function|metal ion binding|,9,0.1,0.142,9,-0.4,2.86,-0.2,1.12,-1.12,0.283,0,0,-1.7,1
ENSMUSG00000092077,OLFR101,olfactory receptor 101,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,3.04,10,-0.1,0.384,0.3,1.12,1.12,0.283,0,0,-1.6,1.2
ENSMUSG00000067629,SYNGAP1,synaptic Ras GTPase activating protein 1 homolog (rat),intracellular|cytoplasm|postsynaptic density|membrane|cell junction|intrinsic component of the cytoplasmic side of the plasma membrane|dendritic shaft|synapse|,signal transduction|Ras protein signal transduction|pattern specification process|visual learning|dendrite development|positive regulation of Ras GTPase activity|positive regulation of Ras GTPase activity|positive regulation of Rab GTPase activity|receptor clustering|regulation of MAPK cascade|negative regulation of neuron apoptotic process|negative regulation of Ras protein signal transduction|negative regulation of Ras protein signal transduction|regulation of synaptic plasticity|regulation of long-term neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|negative regulation of axonogenesis|regulation of synapse structure and activity|regulation of small GTPase mediated signal transduction|,GTPase activator activity|Rab GTPase activator activity|Ras GTPase activator activity|protein binding|SH3 domain binding|protein kinase binding|,10,0.3,2.62,10,-0.3,0.999,0.2,1.12,1.12,0.283,0,0,-1.3,1.4
ENSMUSG00000025780,ITIH5,inter-alpha (globulin) inhibitor H5,cellular_component|extracellular region|,biological_process|negative regulation of peptidase activity|hyaluronan metabolic process|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.4,2.07,10,0,0,-0.4,1.11,-1.11,0.285,0,0,-1.4,1.5
ENSMUSG00000034755,PCDH11X,protocadherin 11 X-linked,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|negative regulation of phosphatase activity|,protein binding|,10,0,0,10,0.4,2.24,0.2,1.1,1.1,0.287,0,0,-0.7,1.8
ENSMUSG00000001700,GRAMD3,GRAM domain containing 3,cytoplasmic microtubule|,biological_process|,molecular_function|,10,0.3,2.09,10,-0.1,0.145,0.2,1.1,1.1,0.287,0,0,-0.9,1.7
ENSMUSG00000068373,D430041D05RIK,RIKEN cDNA D430041D05 gene,cellular_component|,biological_process|,molecular_function|,10,0.7,3.04,10,0.1,0.00795,0.5,1.1,1.1,0.287,0,0,-1,1.9
ENSMUSG00000074673,TTLL9,"tubulin tyrosine ligase-like family, member 9",cellular_component|cytoplasm|cytoskeleton|microtubule|cilium|cell projection|,cellular protein modification process|biological_process|,molecular_function|ligase activity|,10,0.1,0.157,10,0.8,2.89,0.2,1.1,1.1,0.287,0,0,-0.2,2
ENSMUSG00000030669,CALCA,"calcitonin/calcitonin-related polypeptide, alpha",extracellular region|extracellular region|extracellular space|extracellular space|intracellular|nucleus|cytoplasm|axon|axon|neuron projection|neuronal cell body|terminal bouton|,neurological system process involved in regulation of systemic arterial blood pressure|vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure|regulation of heart rate|cellular calcium ion homeostasis|inflammatory response|adenylate cyclase-activating G-protein coupled receptor signaling pathway|activation of adenylate cyclase activity|activation of adenylate cyclase activity|neuropeptide signaling pathway|feeding behavior|regulation of heart contraction|response to heat|negative regulation of ossification|negative regulation of neurological system process|vasodilation|negative regulation of blood pressure|negative regulation of blood pressure|negative regulation of blood pressure|positive regulation of ossification|positive regulation of cell adhesion|negative regulation of smooth muscle contraction|negative regulation of smooth muscle contraction|sperm capacitation|response to pain|regulation of inflammatory response|detection of temperature stimulus involved in sensory perception of pain|,receptor binding|receptor binding|hormone activity|calcitonin receptor binding|calcitonin receptor binding|,10,0.4,2.35,10,0,0,0.3,1.1,1.1,0.287,0,0,-0.8,1.7
ENSMUSG00000020713,GH,growth hormone,extracellular region|extracellular space|extracellular space|nucleus|nucleus|mitochondrion|trans-Golgi network|cytosol|plasma membrane|secretory granule|secretory granule|,signal transduction|neuroblast proliferation|response to light stimulus|glucose transport|response to food|cellular response to insulin stimulus|regulation of intracellular steroid hormone receptor signaling pathway|positive regulation of multicellular organism growth|positive regulation of growth|lung alveolus development|positive regulation of neurogenesis|positive regulation of steroid hormone biosynthetic process|negative regulation of neuron death|,growth hormone receptor binding|growth hormone receptor binding|hormone activity|metal ion binding|,9,0.6,2.16,9,0.1,0.00589,0.4,1.1,1.1,0.287,0,0,-1.6,1.6
ENSMUSG00000036357,GPR101,G protein-coupled receptor 101,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.3,0.938,10,-0.2,0.331,-0.2,1.1,-1.1,0.287,0,0,-1.7,0.8
ENSMUSG00000067571,MS4A15,"membrane-spanning 4-domains, subfamily A, member 15",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,1.55,10,0.1,0.131,-0.1,1.09,-1.09,0.29,0,0,-1.8,0.9
ENSMUSG00000073805,FAM196A,"family with sequence similarity 196, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,1.66,0.2,1.09,1.09,0.29,0,0,-0.8,1.7
ENSMUSG00000027120,FSHB,follicle stimulating hormone beta,extracellular region|cytoplasm|extracellular vesicular exosome|,ovarian follicle development|follicle-stimulating hormone signaling pathway|regulation of osteoclast differentiation|positive regulation of bone resorption|Sertoli cell proliferation|,hormone activity|,10,-0.3,1.3,10,-0.1,0.0145,-0.2,1.09,-1.09,0.29,0,0,-1.7,0.8
ENSMUSG00000022687,BOC,biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein,integral component of plasma membrane|cell surface|membrane|integral component of membrane|axon|growth cone|neuronal cell body|axonal growth cone|,cell adhesion|smoothened signaling pathway|axon guidance|axon guidance|regulation of striated muscle tissue development|single organismal cell-cell adhesion|cell projection organization|positive regulation of myoblast differentiation|,protein binding|,10,-0.1,0.619,10,0.8,4.06,0.8,1.09,1.09,0.29,0,0,-1.2,1.9
ENSMUSG00000038791,SCGB3A2,"secretoglobin, family 3A, member 2",extracellular region|,biological_process|,protein binding|,10,-0.6,2.95,10,-0.1,0.0482,-0.4,1.09,-1.09,0.29,0,0,-1.9,0.6
ENSMUSG00000049010,OLFR982,olfactory receptor 982,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.261,10,0.2,0.919,0.2,1.09,1.09,0.29,0,0,-0.9,1.7
ENSMUSG00000021852,SLC35F4,"solute carrier family 35, member F4",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0.1,0.394,10,-0.3,1.96,-0.3,1.08,-1.08,0.292,0,0,-1.6,1
ENSMUSG00000025189,CNNM1,cyclin M1,plasma membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|adenyl nucleotide binding|,10,0.5,3.53,10,0,0,0.4,1.08,1.08,0.292,0,0,-0.6,1.9
ENSMUSG00000003354,CCDC65,coiled-coil domain containing 65,cellular_component|,biological_process|,molecular_function|,10,0.3,2.85,10,0,0,0.3,1.08,1.08,0.292,0,0,-1.1,1.5
ENSMUSG00000046856,GPR1,G protein-coupled receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.3,1.86,10,0,0,0.2,1.08,1.08,0.292,0,0,-1.5,1.2
ENSMUSG00000053368,RXFP2,relaxin/insulin-like family peptide receptor 2,plasma membrane|membrane|integral component of membrane|,oocyte maturation|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway|negative regulation of cell proliferation|male gonad development|positive regulation of cAMP biosynthetic process|negative regulation of apoptotic process|,signal transducer activity|G-protein coupled receptor activity|protein-hormone receptor activity|peptide hormone binding|,10,0.1,0.0697,10,0.2,1.43,0.2,1.08,1.08,0.292,0,0,-1,1.6
ENSMUSG00000034981,PARM1,prostate androgen-regulated mucin-like protein 1,endosome|early endosome|late endosome|Golgi apparatus|plasma membrane|membrane|integral component of membrane|,positive regulation of telomerase activity|,molecular_function|,10,-0.4,2.09,10,0.1,0.0716,-0.2,1.08,-1.08,0.292,0,0,-1.4,1.2
ENSMUSG00000021187,TC2N,"tandem C2 domains, nuclear",nucleus|,regulation of gene expression|regulation of blood coagulation|,molecular_function|,10,0.3,2.4,10,-0.1,0.358,0.2,1.08,1.08,0.292,0,0,-1,1.6
ENSMUSG00000023036,PCDHGA9,"protocadherin gamma subfamily A, 9",membrane|,biological_process|,poly(A) RNA binding|,10,-0.4,2.89,10,0.2,0.545,-0.2,1.08,-1.08,0.292,0,0,-1.7,1
ENSMUSG00000043605,OLFR13,olfactory receptor 13,plasma membrane|membrane|integral component of membrane|cleavage furrow|recycling endosome|Flemming body|mitotic spindle pole|mitotic spindle midzone|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,0.253,10,0.2,0.95,0.3,1.07,1.07,0.294,0,0,-1,1.6
ENSMUSG00000040367,LRRD1,leucine rich repeats and death domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0.9,2.54,10,0.1,0.328,0.2,1.07,1.07,0.294,0,0,-0.3,2
ENSMUSG00000075197,OLFR1046,olfactory receptor 1046,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,1.49,10,0.2,0.605,-0.2,1.05,-1.05,0.298,0,0,-1.4,1.2
ENSMUSG00000094531,OLFR671,olfactory receptor 671,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.8,2.25,-0.2,1.05,-1.05,0.298,0,0,-2,1
ENSMUSG00000068082,GRXCR1,"glutaredoxin, cysteine rich 1",cilium|stereocilium|cell projection|kinocilium|,sensory perception of sound|negative regulation of phosphatase activity|auditory receptor cell differentiation|cell redox homeostasis|post-embryonic organ morphogenesis|inner ear development|vestibular receptor cell development|inner ear receptor cell development|inner ear receptor stereocilium organization|,molecular_function|electron carrier activity|protein disulfide oxidoreductase activity|,10,0.3,2.53,9,0,0,0.2,1.04,1.04,0.3,0,0,-0.7,1.9
ENSMUSG00000029867,1700034O15RIK,RIKEN cDNA 1700034O15 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.4,2.22,10,0,0,-0.2,1.04,-1.04,0.3,0,0,-1.7,0.9
ENSMUSG00000074715,CCL28,chemokine (C-C motif) ligand 28,extracellular region|extracellular space|extracellular vesicular exosome|,chemotaxis|immune response|positive regulation of cytosolic calcium ion concentration|cell chemotaxis|,cytokine activity|chemokine activity|,10,-0.2,0.247,10,-0.4,1.23,-0.3,1.04,-1.04,0.3,0,0,-1.8,0.6
ENSMUSG00000098176,CCDC166,coiled-coil domain containing 166,cellular_component|,biological_process|,molecular_function|,10,0.5,3.52,10,0,0,0.5,1.04,1.04,0.3,0,0,-0.7,1.8
ENSMUSG00000046082,TMEM174,transmembrane protein 174,cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,2.18,10,0.4,0.476,-0.2,1.04,-1.04,0.3,0,0,-1.5,1.4
ENSMUSG00000043924,NCMAP,noncompact myelin associated protein,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|paranode region of axon|Schmidt-Lanterman incisure|,positive regulation of myelination|peripheral nervous system myelin formation|,structural constituent of myelin sheath|,10,-0.3,0.949,10,-0.2,0.25,-0.2,1.04,-1.04,0.3,0,0,-1.5,1.1
ENSMUSG00000017733,EPPIN,epididymal peptidase inhibitor,acrosomal vesicle|extracellular region|cytoplasm|,negative regulation of peptidase activity|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.3,0.916,10,-0.2,0.259,-0.2,1.03,-1.03,0.302,0,0,-1.7,0.9
ENSMUSG00000042873,LHFPL4,lipoma HMGIC fusion partner-like protein 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.33,10,-0.1,0.00615,-0.3,1.03,-1.03,0.302,0,0,-1.9,0.5
ENSMUSG00000069670,NKAIN2,Na+/K+ transporting ATPase interacting 2,plasma membrane|membrane|integral component of membrane|,None,None,10,0.3,1.71,10,0,0,0.3,1.03,1.03,0.302,0,0,-0.8,1.7
ENSMUSG00000073705,APITD1,"apoptosis-inducing, TAF9-like domain 1","chromosome, centromeric region|kinetochore|nucleus|chromosome|Fanconi anaemia nuclear complex|FANCM-MHF complex|",DNA repair|cellular response to DNA damage stimulus|cell cycle|mitotic nuclear division|cell division|,DNA binding|chromatin binding|double-stranded DNA binding|protein heterodimerization activity|,9,-0.2,0.382,9,0.2,0.959,0.1,1.02,1.02,0.304,0,0,-1.1,1.7
ENSMUSG00000027445,CST9,cystatin 9,extracellular region|,negative regulation of peptidase activity|,cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.3,1.3,10,0.1,0.0525,0.3,1.02,1.02,0.304,0,0,-0.8,1.7
ENSMUSG00000033774,NPBWR1,neuropeptides B/W receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|regulation of metabolic process|,signal transducer activity|G-protein coupled receptor activity|neuropeptide receptor activity|,10,0.1,0.335,10,0.2,0.79,0.1,1.02,1.02,0.304,0,0,-0.7,1.8
ENSMUSG00000044337,ACKR3,atypical chemokine receptor 3,cytoplasm|endosome|plasma membrane|coated pit|cell surface|membrane|integral component of membrane|,angiogenesis|vasculogenesis|chemotaxis|cell adhesion|signal transduction|G-protein coupled receptor signaling pathway|multicellular organismal development|receptor internalization|chemokine-mediated signaling pathway|positive regulation of ERK1 and ERK2 cascade|negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|scavenger receptor activity|coreceptor activity|C-X-C chemokine receptor activity|C-X-C chemokine binding|,10,0.1,0.239,10,0.2,0.962,0.2,1.02,1.02,0.304,0,0,-0.8,1.8
ENSMUSG00000047495,DLGAP2,"discs, large (Drosophila) homolog-associated protein 2",plasma membrane|membrane|cell junction|dendrite|synapse|postsynaptic membrane|,cell-cell signaling|biological_process|,protein domain specific binding|,10,-0.2,1.36,10,0,0,-0.2,1.01,-1.01,0.306,0,0,-1.8,0.8
ENSMUSG00000075220,OLFR993,olfactory receptor 993,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.581,10,-0.2,0.685,-0.1,1.01,-1.01,0.306,0,0,-1.7,0.9
ENSMUSG00000078129,ACTL10,actin-like 10,cellular_component|,biological_process|,molecular_function|,10,-0.8,3.3,10,0,0,-0.6,1.01,-1.01,0.306,0,0,-2,0.3
ENSMUSG00000030484,LYPD5,Ly6/Plaur domain containing 5,cellular_component|plasma membrane|membrane|anchored component of membrane|,biological_process|,molecular_function|,10,0.1,0.000499,10,0.3,1.5,0.2,1.01,1.01,0.306,0,0,-2,1
ENSMUSG00000046387,PCDHB17,protocadherin beta 17,plasma membrane|membrane|integral component of membrane|,cell adhesion|,molecular_function|,10,-0.1,0.255,10,0.7,2.63,0.5,1.01,1.01,0.306,0,0,-0.6,1.9
ENSMUSG00000041872,IL17F,interleukin 17F,extracellular region|extracellular space|,proteoglycan metabolic process|inflammatory response|negative regulation of angiogenesis|regulation of transforming growth factor beta receptor signaling pathway|cytokine biosynthetic process|lymphotoxin A biosynthetic process|regulation of interleukin-2 biosynthetic process|regulation of interleukin-6 biosynthetic process|regulation of interleukin-8 biosynthetic process|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|cartilage development|positive regulation of cytokine production involved in inflammatory response|positive regulation of cytokine production involved in inflammatory response|,cytokine activity|cytokine receptor binding|cytokine binding|protein homodimerization activity|,10,0.3,1.61,10,-0.1,0.223,0.2,1.01,1.01,0.306,0,0,-1.2,1.5
ENSMUSG00000034310,TMEM132D,transmembrane protein 132D,cellular_component|membrane|integral component of membrane|,negative regulation of phosphatase activity|,molecular_function|,10,-0.2,0.836,10,-0.1,0.311,-0.2,1,-1,0.308,0,0,-1.6,1
ENSMUSG00000026835,FCNB,ficolin B,extracellular region|collagen trimer|,"complement activation, lectin pathway|immune system process|innate immune response|",sialic acid binding|carbohydrate derivative binding|,10,0,0,10,0.2,1.24,0.2,1,1,0.308,0,0,-2,1
ENSMUSG00000036264,FSTL4,follistatin-like 4,extracellular region|,None,calcium ion binding|metal ion binding|,10,-0.3,2.14,10,0.1,0.401,-0.2,1,-1,0.308,0,0,-1.6,0.9
ENSMUSG00000050431,OLFR730,olfactory receptor 730,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,1.53,10,0.2,0.522,-0.2,0.999,-0.999,0.308,0,0,-1.4,1.3
ENSMUSG00000048779,P2RY6,"pyrimidinergic receptor P2Y, G-protein coupled, 6",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of smooth muscle cell migration|transepithelial chloride transport|,signal transducer activity|G-protein coupled receptor activity|pyrimidine nucleotide binding|G-protein coupled purinergic nucleotide receptor activity|UDP-activated nucleotide receptor activity|,10,-0.2,0.178,10,-0.4,1.05,-0.3,0.995,-0.995,0.309,0,0,-1.8,0.7
ENSMUSG00000045915,CCDC42,coiled-coil domain containing 42,cellular_component|,biological_process|,molecular_function|,10,1.2,2.93,10,0.2,0.12,1.1,0.992,0.992,0.31,0,0,-0.6,2
ENSMUSG00000094669,OLFR441,olfactory receptor 441,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.61,10,0,0,0.2,0.992,0.992,0.31,0,0,-1.4,1.3
ENSMUSG00000046056,SBSN,suprabasin,extracellular region|cytoplasm|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.1,0.489,10,-0.2,0.681,-0.2,0.992,-0.992,0.31,0,0,-1.8,0.7
ENSMUSG00000038537,MC3R,melanocortin 3 receptor,plasma membrane|membrane|integral component of membrane|,regulation of heart rate|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|regulation of blood pressure|positive regulation of cAMP biosynthetic process|homoiothermy|,signal transducer activity|G-protein coupled receptor activity|melanocortin receptor activity|melanocyte-stimulating hormone receptor activity|melanocyte-stimulating hormone receptor activity|protein binding|peptide hormone binding|neuropeptide binding|,10,0.2,0.416,10,0.2,0.664,0.2,0.992,0.992,0.31,0,0,-0.8,1.8
ENSMUSG00000068794,COL28A1,"collagen, type XXVIII, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|basement membrane|,cell adhesion|biological_process|negative regulation of peptidase activity|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.2,0.277,10,-0.2,0.792,-0.2,0.984,-0.984,0.312,0,0,-1.7,1
ENSMUSG00000047298,KCNV2,"potassium channel, subfamily V, member 2",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.4,2.96,10,0,0,0.3,0.982,0.982,0.312,0,0,-0.5,1.9
ENSMUSG00000044375,BC027072,cDNA sequence BC027072,cilium|cell projection|primary cilium|,visual perception|response to stimulus|detection of light stimulus involved in visual perception|,molecular_function|,10,0.2,0.277,10,0.2,0.789,0.2,0.981,0.981,0.312,0,0,-0.9,1.8
ENSMUSG00000049719,PRSS46,"protease, serine 46",cellular_component|membrane|integral component of membrane|,proteolysis|biological_process|,molecular_function|catalytic activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,0.1,0.18,10,0.4,1.37,0.2,0.979,0.979,0.313,0,0,-0.9,1.7
ENSMUSG00000043267,OLFR1031,olfactory receptor 1031,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,-0.2,0.8,9,-0.1,0.284,-0.2,0.978,-0.978,0.313,0,0,-1.5,1.3
ENSMUSG00000096029,OLFR679,olfactory receptor 679,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.9,1.73,10,0.2,0.441,0.3,0.971,0.971,0.314,0,0,-1.8,1.3
ENSMUSG00000070683,LACTBL1,"lactamase, beta-like 1",cellular_component|,biological_process|,molecular_function|,10,-0.5,2.8,10,0,0,-0.3,0.97,-0.97,0.315,0,0,-1.6,0.9
ENSMUSG00000075224,LRRC55,leucine rich repeat containing 55,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,-0.1,0.233,10,-0.5,1.51,-0.3,0.967,-0.967,0.315,0,0,-1.8,0.8
ENSMUSG00000055541,LAIR1,leukocyte-associated Ig-like receptor 1,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,None,None,10,-0.3,0.709,10,0.2,0.996,-0.4,0.967,-0.967,0.315,0,0,-1.5,1.1
ENSMUSG00000048029,ENO4,enolase 4,phosphopyruvate hydratase complex|sperm principal piece|,glycolytic process|sperm motility|cilium organization|,magnesium ion binding|phosphopyruvate hydratase activity|protein binding|protein heterodimerization activity|,10,0.1,0.151,10,0.2,1.29,0.1,0.966,0.966,0.315,0,0,-1.3,1.4
ENSMUSG00000027403,TGM6,transglutaminase 6,cytoplasm|,biological_process|,"protein-glutamine gamma-glutamyltransferase activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,-0.1,0.275,10,-0.2,0.79,-0.2,0.965,-0.965,0.316,0,0,-1.8,0.7
ENSMUSG00000078611,GM5901,predicted gene 5901,cellular_component|,biological_process|,molecular_function|,10,0.2,0.519,10,0.3,0.727,0.3,0.963,0.963,0.316,0,0,-1.1,1.6
ENSMUSG00000028533,IZUMO3,IZUMO family member 3,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,protein homodimerization activity|,10,0,0,10,0.8,2.71,0.2,0.961,0.961,0.317,0,0,-0.6,2
ENSMUSG00000027022,XIRP2,xin actin-binding repeat containing 2,Z disc|cell junction|,ventricular septum development|actin cytoskeleton organization|cell-cell junction organization|cardiac muscle tissue morphogenesis|,actin binding|protein binding|zinc ion binding|metal ion binding|alpha-actinin binding|,10,-0.3,0.179,10,-0.4,0.932,-0.4,0.959,-0.959,0.317,0,0,-1.9,0.4
ENSMUSG00000073514,DOK6,docking protein 6,cellular_component|,biological_process|,molecular_function|insulin receptor binding|,10,-1.2,2.64,10,-0.1,0.0264,-0.1,0.959,-0.959,0.317,0,0,-2,0.3
ENSMUSG00000045657,PCDHB10,protocadherin beta 10,plasma membrane|membrane|integral component of membrane|,cell adhesion|,molecular_function|,9,0.1,0.136,9,0.6,1.5,0.1,0.951,0.951,0.319,0,0,-1.3,1.6
ENSMUSG00000022123,SCEL,sciellin,cytoplasm|cytoplasm|membrane|extracellular vesicular exosome|,epidermis development|embryo development|keratinocyte differentiation|,zinc ion binding|metal ion binding|,10,0.1,0.0965,10,-0.3,1.44,-0.2,0.95,-0.95,0.319,0,0,-1.2,1.5
ENSMUSG00000025321,ITGB8,integrin beta 8,membrane|integral component of membrane|extracellular vesicular exosome|,ganglioside metabolic process|cell adhesion|integrin-mediated signaling pathway|,receptor binding|,10,0.1,0.0246,10,0.3,1.33,0.2,0.944,0.944,0.32,0,0,-1.8,1.1
ENSMUSG00000071104,CCDC110,coiled-coil domain containing 110,nucleus|,biological_process|,molecular_function|,10,-0.4,1.6,10,0.1,0.032,-0.2,0.935,-0.935,0.322,0,0,-1.8,0.9
ENSMUSG00000045648,VWC2L,von Willebrand factor C domain-containing protein 2-like,extracellular region|extracellular space|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|,multicellular organismal development|negative regulation of BMP signaling pathway|positive regulation of neuron differentiation|,molecular_function|,10,0.3,0.369,10,-0.5,1.51,-0.2,0.935,-0.935,0.322,0,0,-1.5,1.6
ENSMUSG00000031130,BRS3,bombesin-like receptor 3,plasma membrane|membrane|integral component of membrane|neuron projection|neuronal cell body|,signal transduction|G-protein coupled receptor signaling pathway|bombesin receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|bombesin receptor activity|,10,-0.8,3.31,10,0.3,0.704,-0.5,0.93,-0.93,0.323,0,0,-2,0.7
ENSMUSG00000032289,THSD4,"thrombospondin, type I, domain containing 4",microfibril|extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular vesicular exosome|,elastic fiber assembly|,metalloendopeptidase activity|protein binding|peptidase activity|hydrolase activity|,10,0,0,10,-0.4,1.9,-0.3,0.929,-0.929,0.324,0,0,-1.6,1
ENSMUSG00000020583,MATN3,matrilin 3,extracellular region|proteinaceous extracellular matrix|,None,calcium ion binding|,10,0.2,0.603,10,0.8,1.36,0.2,0.929,0.929,0.324,0,0,-0.5,2
ENSMUSG00000069763,TMEM100,transmembrane protein 100,intracellular|cytoplasm|endoplasmic reticulum|plasma membrane|plasma membrane|membrane|integral component of membrane|perikaryon|perikaryon|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,angiogenesis|vasculogenesis|in utero embryonic development|Notch signaling pathway|multicellular organismal development|cell differentiation|BMP signaling pathway|protein kinase B signaling|positive regulation of endothelial cell differentiation|arterial endothelial cell differentiation|cellular response to BMP stimulus|positive regulation of vasculogenesis|,molecular_function|,10,0.3,0.386,10,0.2,0.646,0.2,0.927,0.927,0.324,0,0,-0.7,1.9
ENSMUSG00000020090,NPFFR1,neuropeptide FF receptor 1,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,9,-1.2,2.85,9,-0.2,0.453,0.2,0.927,0.927,0.324,0,0,-2,0.6
ENSMUSG00000051397,TACSTD2,tumor-associated calcium signal transducer 2,extracellular space|nucleus|plasma membrane|basal plasma membrane|membrane|integral component of membrane|lateral plasma membrane|extracellular vesicular exosome|,negative regulation of epithelial cell migration|negative regulation of stress fiber assembly|negative regulation of branching involved in ureteric bud morphogenesis|negative regulation of substrate adhesion-dependent cell spreading|negative regulation of ruffle assembly|negative regulation of cell motility|positive regulation of stem cell differentiation|,molecular_function|,10,-0.3,1.27,10,-0.1,0.0133,-0.3,0.924,-0.924,0.325,0,0,-1.4,1.4
ENSMUSG00000030109,SLC6A12,"solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12",integral component of plasma membrane|membrane|integral component of membrane|,transport|neurotransmitter transport|cellular water homeostasis|,neurotransmitter:sodium symporter activity|gamma-aminobutyric acid:sodium symporter activity|symporter activity|,10,-0.5,2.01,10,0.1,0.0458,-0.2,0.924,-0.924,0.325,0,0,-1.7,1.2
ENSMUSG00000053395,CACNG8,"calcium channel, voltage-dependent, gamma subunit 8",plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|postsynaptic membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,voltage-gated ion channel activity|calcium channel activity|,10,-0.3,1.71,10,0,0,-0.3,0.922,-0.922,0.325,0,0,-1.8,0.7
ENSMUSG00000022900,ILDR1,immunoglobulin-like domain containing receptor 1,plasma membrane|membrane|integral component of membrane|,receptor-mediated endocytosis|positive regulation of peptide hormone secretion|,high-density lipoprotein particle receptor activity|,10,-0.1,0.5,10,0.6,3.39,0.5,0.92,0.92,0.325,0,0,-0.6,1.9
ENSMUSG00000020213,GLIPR1L1,GLI pathogenesis-related 1 like 1,acrosomal vesicle|sperm connecting piece|,binding of sperm to zona pellucida|,molecular_function|,10,0.4,1.99,10,0,0,0.2,0.918,0.918,0.326,0,0,-1.1,1.5
ENSMUSG00000095028,SIRPB1B,signal-regulatory protein beta 1B,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.3,2.18,10,0.4,1.59,-0.2,0.917,-0.917,0.326,0,0,-1.2,1.5
ENSMUSG00000043787,DEFB12,defensin beta 12,cellular_component|extracellular region|,defense response|defense response to bacterium|defense response to Gram-negative bacterium|,molecular_function|,7,-0.2,1.41,8,0.5,0.122,-0.2,0.916,-0.916,0.326,0,0,-1.9,1.1
ENSMUSG00000095957,OLFR832,olfactory receptor 832,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.339,10,-0.4,1.27,-0.2,0.915,-0.915,0.327,0,0,-1.7,0.8
ENSMUSG00000046699,SLITRK4,"SLIT and NTRK-like family, member 4",membrane|integral component of membrane|,axonogenesis|,molecular_function|,10,-0.1,0.401,10,-0.2,0.627,-0.2,0.914,-0.914,0.327,0,0,-1.6,1
ENSMUSG00000096140,ANKRD66,ankyrin repeat domain 66,None,None,None,10,0,0,10,0.2,1.22,0.2,0.914,0.914,0.327,0,0,-0.7,1.8
ENSMUSG00000072791,ABCB5,"ATP-binding cassette, sub-family B (MDR/TAP), member 5",integral component of plasma membrane|integral component of membrane|,"antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent|antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent|antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent|positive regulation of antigen processing and presentation of peptide antigen via MHC class I|ATP catabolic process|regulation of membrane potential|transmembrane transport|transmembrane transport|","nucleotide binding|ATP binding|efflux transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of substances|",10,0.4,1.38,10,0.1,0.0616,0.2,0.913,0.913,0.327,0,0,-0.7,1.8
ENSMUSG00000043259,FAM13C,"family with sequence similarity 13, member C",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.5,2.74,-0.2,0.912,-0.912,0.327,0,0,-2,0.6
ENSMUSG00000046818,DDIT4L,DNA-damage-inducible transcript 4-like,cellular_component|cytoplasm|,biological_process|negative regulation of signal transduction|,molecular_function|,10,-0.2,1.29,10,0.1,0.0826,-0.2,0.91,-0.91,0.328,0,0,-1.7,1
ENSMUSG00000030108,SLC6A13,"solute carrier family 6 (neurotransmitter transporter, GABA), member 13",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,amino acid transmembrane transport|transport|neurotransmitter transport|gamma-aminobutyric acid transport|sodium ion transmembrane transport|,neurotransmitter:sodium symporter activity|gamma-aminobutyric acid:sodium symporter activity|symporter activity|neurotransmitter binding|,10,-0.1,0.421,10,-0.2,0.618,-0.2,0.907,-0.907,0.328,0,0,-1.6,1.1
ENSMUSG00000019785,CLVS2,clavesin 2,intracellular|endosome|Golgi apparatus|trans-Golgi network|membrane|clathrin-coated vesicle|cytoplasmic vesicle|,transport|lysosome organization|,"transporter activity|lipid binding|phosphatidylinositol-3,5-bisphosphate binding|",9,-0.2,1.69,9,0,0,-0.2,0.906,-0.906,0.328,0,0,-1.9,0.9
ENSMUSG00000020422,TNS3,tensin 3,cytoplasm|focal adhesion|cell junction|,positive regulation of cell proliferation|cell migration|lung alveolus development|,molecular_function|metal ion binding|,10,-0.7,2.93,10,0,0,-0.5,0.906,-0.906,0.328,0,0,-2,0.4
ENSMUSG00000028655,MFSD2A,major facilitator superfamily domain containing 2A,cytoplasm|endoplasmic reticulum|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|lipid transport|fatty acid transport|transcytosis|establishment of blood-brain barrier|lipid transport across blood brain barrier|,phospholipid transporter activity|symporter activity|symporter activity|,10,0.2,0.352,10,0.1,0.665,0.2,0.905,0.905,0.329,0,0,-1.6,1.2
ENSMUSG00000020839,TMIGD1,transmembrane and immunoglobulin domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,2.06,10,0,0,0.2,0.905,0.905,0.329,0,0,-1.1,1.7
ENSMUSG00000073408,DPCR1,diffuse panbronchiolitis critical region 1 (human),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,2.47,10,-0.3,1.42,0.2,0.904,0.904,0.329,0,0,-1.3,1.3
ENSMUSG00000032204,AQP9,aquaporin 9,integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|intracellular membrane-bounded organelle|pore complex|,transport|ion transport|water transport|water transport|purine nucleobase transport|response to organic substance|canalicular bile acid transport|polyol transport|glycerol transport|amine transport|pyrimidine nucleobase transport|nucleobase-containing compound transport|carbohydrate transmembrane transport|response to mercury ion|transmembrane transport|pyrimidine-containing compound transmembrane transport|,transporter activity|purine nucleobase transmembrane transporter activity|pyrimidine nucleobase transmembrane transporter activity|water channel activity|water channel activity|glycerol channel activity|porin activity|,10,0.1,0.223,10,0.1,0.758,0.1,0.903,0.903,0.329,0,0,-1.1,1.6
ENSMUSG00000040485,LRRC52,leucine rich repeat containing 52,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0,0,10,0.8,2.38,0.2,0.901,0.901,0.329,0,0,-0.4,2
ENSMUSG00000067879,3110035E14RIK,RIKEN cDNA 3110035E14 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.605,10,0.2,0.375,0.2,0.9,0.9,0.33,0,0,-0.9,1.7
ENSMUSG00000074825,ITPRIPL1,"inositol 1,4,5-triphosphate receptor interacting protein-like 1",membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.406,10,0.3,2.51,0.2,0.9,0.9,0.33,0,0,-1.2,1.5
ENSMUSG00000026416,IL20,interleukin 20,extracellular region|extracellular space|intracellular|cell|,STAT protein import into nucleus|hemopoiesis|positive regulation of osteoclast differentiation|,receptor binding|cytokine activity|cytokine activity|interleukin-20 receptor binding|interleukin-20 receptor binding|interleukin-22 receptor binding|,10,0.2,0.618,10,0.7,0.993,0.2,0.898,0.898,0.33,0,0,-0.6,2
ENSMUSG00000025489,IFITM5,interferon induced transmembrane protein 5,plasma membrane|plasma membrane|membrane|integral component of membrane|,multicellular organismal development|response to biotic stimulus|bone mineralization|regulation of bone mineralization|,molecular_function|,10,0.3,1.57,10,0,0,0.2,0.897,0.897,0.33,0,0,-0.6,1.9
ENSMUSG00000058200,OLFR66,olfactory receptor 66,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.493,10,-0.2,0.502,-0.1,0.896,-0.896,0.331,0,0,-1.8,1.3
ENSMUSG00000001622,CSN3,casein kappa,extracellular region|extracellular space|,lactation|lactation|protein stabilization|,molecular_function|,10,-0.4,2.52,10,0.4,0.665,-0.2,0.896,-0.896,0.331,0,0,-1.7,1.2
ENSMUSG00000049098,OLFR147,olfactory receptor 147,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,1.02,10,-0.1,0.0856,-0.1,0.895,-0.895,0.331,0,0,-1.7,1
ENSMUSG00000025497,CDHR5,cadherin-related family member 5,plasma membrane|coated pit|membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|,calcium ion binding|beta-catenin binding|,9,-0.3,0.912,9,-0.1,0.181,-0.2,0.894,-0.894,0.331,0,0,-1.8,0.9
ENSMUSG00000075566,KRTAP4-6,keratin associated protein 4-6,cellular_component|intermediate filament|,biological_process|,protein binding|,10,0,0,10,0.3,1.83,0.2,0.89,0.89,0.332,0,0,-0.6,1.8
ENSMUSG00000040373,CACNG5,"calcium channel, voltage-dependent, gamma subunit 5",plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|synapse|postsynaptic membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,voltage-gated ion channel activity|calcium channel activity|,10,0.2,0.845,10,0.1,0.255,0.1,0.887,0.887,0.333,0,0,-0.9,1.7
ENSMUSG00000021804,RGR,retinal G protein coupled receptor,integral component of plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|visual perception|phototransduction|protein-chromophore linkage|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|photoreceptor activity|,10,-0.2,1.11,10,0.1,0.266,-0.1,0.887,-0.887,0.333,0,0,-1.6,1.1
ENSMUSG00000045441,GPRIN3,GPRIN family member 3,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,1.83,-0.2,0.886,-0.886,0.333,0,0,-1.6,1
ENSMUSG00000021336,SLC17A4,"solute carrier family 17 (sodium phosphate), member 4",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,-0.1,0.0608,10,-0.3,1.16,-0.3,0.885,-0.885,0.333,0,0,-1.6,1.2
ENSMUSG00000042367,GJB3,"gap junction protein, beta 3",cytoplasm|plasma membrane|cell-cell junction|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,placenta development|cell communication|sensory perception of sound|,protein binding|,10,-0.3,0.768,10,-0.1,0.38,-0.2,0.885,-0.885,0.333,0,0,-1.7,1
ENSMUSG00000047307,PCDHB13,protocadherin beta 13,plasma membrane|membrane|integral component of membrane|,cell adhesion|,None,10,-0.2,1.26,10,0.3,1.43,0.2,0.884,0.884,0.333,0,0,-1.6,1.2
ENSMUSG00000074872,CTXN2,cortexin 2,cellular_component|membrane|integral component of membrane|intrinsic component of membrane|,biological_process|,molecular_function|,10,0.2,0.657,10,0.2,0.3,0.2,0.879,0.879,0.335,0,0,-1.2,1.5
ENSMUSG00000027171,PRRG4,proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane),extracellular region|membrane|integral component of membrane|,biological_process|,molecular_function|calcium ion binding|,10,0.2,1,10,0,0,0.2,0.87,0.87,0.337,0,0,-1.1,1.6
ENSMUSG00000075190,OLFR1054,olfactory receptor 1054,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.039,10,-0.7,1.96,0.3,0.869,0.869,0.337,0,0,-1.7,1.1
ENSMUSG00000058728,CD300C,CD300C antigen,cellular_component|plasma membrane|membrane|integral component of membrane|,immune system process|biological_process|,molecular_function|,10,-0.3,0.982,10,0.2,0.693,-0.2,0.868,-0.868,0.337,0,0,-1.5,1.1
ENSMUSG00000047798,CD300LF,CD300 antigen like family member F,plasma membrane|membrane|integral component of membrane|,immune system process|osteoclast differentiation|,protein binding|,10,-0.2,0.845,10,-0.1,0.172,-0.2,0.859,-0.859,0.34,0,0,-1.6,1
ENSMUSG00000071356,REG3B,regenerating islet-derived 3 beta,extracellular region|,acute-phase response|inflammatory response|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|,carbohydrate binding|,10,0.3,1.34,10,-0.3,1.42,-0.2,0.859,-0.859,0.34,0,0,-1.4,1.2
ENSMUSG00000004383,LARGE,like-glycosyltransferase,Golgi apparatus|membrane|integral component of membrane|,glycoprotein biosynthetic process|muscle cell cellular homeostasis|,"protein binding|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.3,1.61,10,0.2,0.194,-0.3,0.858,-0.858,0.34,0,0,-1.8,1
ENSMUSG00000091345,COL6A5,"collagen, type VI, alpha 5",extracellular region|proteinaceous extracellular matrix|collagen trimer|,cell adhesion|,molecular_function|,10,-0.2,1.4,10,0.1,0.0739,-0.2,0.853,-0.853,0.341,0,0,-1,1.7
ENSMUSG00000060487,SAMD5,sterile alpha motif domain containing 5,cellular_component|,biological_process|,molecular_function|,8,0,0,8,0.7,1.88,-0.3,0.853,-0.853,0.341,0,0,-1.2,1.9
ENSMUSG00000024757,SLC22A19,"solute carrier family 22 (organic anion transporter), member 19",membrane|integral component of membrane|apical plasma membrane|,response to molecule of fungal origin|organic anion transport|organic anion transport|ion transmembrane transport|toxin transport|,organic anion transmembrane transporter activity|organic anion transmembrane transporter activity|toxin transporter activity|,10,-0.3,1.49,10,0.1,0.0545,-0.2,0.852,-0.852,0.341,0,0,-1.7,0.9
ENSMUSG00000023393,SLC17A9,"solute carrier family 17, member 9",membrane|integral component of membrane|,transport|exocytosis|transmembrane transport|,transporter activity|,10,0.3,1.85,10,-0.3,0.842,0.2,0.852,0.852,0.341,0,0,-1.2,1.4
ENSMUSG00000068196,COL8A1,"collagen, type VIII, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|basement membrane|extracellular matrix|intracellular membrane-bounded organelle|extracellular vesicular exosome|,angiogenesis|cell adhesion|positive regulation of cell-substrate adhesion|camera-type eye morphogenesis|epithelial cell proliferation|,None,10,0.4,0.982,10,0.1,0.298,0.2,0.846,0.846,0.343,0,0,-0.9,1.7
ENSMUSG00000094398,OLFR1360,olfactory receptor 1360,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,1.36,10,0,0,0.2,0.845,0.845,0.343,0,0,-1.4,1.3
ENSMUSG00000035694,CAPS2,calcyphosphine 2,cellular_component|,biological_process|,molecular_function|calcium ion binding|metal ion binding|,10,-0.2,0.462,10,0.8,1.2,-0.2,0.843,-0.843,0.343,0,0,-1.1,1.9
ENSMUSG00000079278,TMEM233,transmembrane protein 233,cellular_component|membrane|integral component of membrane|,biological_process|response to biotic stimulus|,molecular_function|,10,0.1,0.49,10,0.2,0.552,0.2,0.839,0.839,0.344,0,0,-1,1.7
ENSMUSG00000027674,PEX5L,peroxisomal biogenesis factor 5-like,cytoplasm|peroxisomal membrane|cytosol|cytosol|membrane|intracellular cyclic nucleotide activated cation channel complex|dendrite|receptor complex|perinuclear region of cytoplasm|cell tip|,"cation transport|protein import into peroxisome matrix|protein import into peroxisome matrix, docking|ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|regulation of cAMP-mediated signaling|regulated secretory pathway|maintenance of protein location|positive regulation of corticotropin secretion|",peroxisome targeting sequence binding|peroxisome matrix targeting signal-1 binding|peroxisome matrix targeting signal-1 binding|intracellular cyclic nucleotide activated cation channel activity|protein binding|Rab GTPase binding|small GTPase binding|,10,-0.3,1.44,10,-0.1,0.226,-0.3,0.839,-0.839,0.344,0,0,-1.8,0.9
ENSMUSG00000030553,PGPEP1L,pyroglutamyl-peptidase I-like,cellular_component|cytosol|,proteolysis|biological_process|,molecular_function|peptidase activity|cysteine-type peptidase activity|hydrolase activity|pyroglutamyl-peptidase activity|,10,0.5,1.58,10,0.1,0.14,0.2,0.839,0.839,0.344,0,0,-0.8,1.8
ENSMUSG00000056632,DSG3,desmoglein 3,plasma membrane|integral component of plasma membrane|spot adherens junction|membrane|integral component of membrane|cell junction|desmosome|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|,calcium ion binding|metal ion binding|,10,0.2,1.12,10,-0.1,0.122,0.1,0.839,0.839,0.344,0,0,-1.1,1.7
ENSMUSG00000006711,D130043K22RIK,RIKEN cDNA D130043K22 gene,endosome|early endosome|plasma membrane|membrane|integral component of membrane|,neuron migration|multicellular organismal development|nervous system development|negative regulation of dendrite development|,molecular_function|,10,-0.3,1.64,10,0.2,0.149,-0.1,0.839,-0.839,0.344,0,0,-1.7,1
ENSMUSG00000036437,NPY1R,neuropeptide Y receptor Y1,cytosol|plasma membrane|synaptic vesicle|membrane|integral component of membrane|axon|,outflow tract morphogenesis|glucose metabolic process|signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|locomotory behavior|feeding behavior|regulation of blood pressure|sensory perception of pain|sensory perception of pain|peristalsis|regulation of multicellular organism growth|positive regulation of vasoconstriction|negative regulation of hormone secretion|negative regulation of cytosolic calcium ion concentration|,peptide YY receptor activity|pancreatic polypeptide receptor activity|signal transducer activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|,10,0.5,3.4,10,0,0,0.4,0.834,0.834,0.346,0,0,-0.4,1.9
ENSMUSG00000032878,CCDC85A,coiled-coil domain containing 85A,cellular_component|,biological_process|,molecular_function|,10,0.6,3.5,10,-0.1,0.244,0.6,0.833,0.833,0.346,0,0,-0.7,1.9
ENSMUSG00000051669,AU021092,expressed sequence AU021092,extracellular region|cytosol|membrane|extracellular vesicular exosome|,biological_process|,protein homodimerization activity|,10,0.4,3,10,-1.5,2.5,-0.1,0.829,-0.829,0.347,0,0,-3,0.8
ENSMUSG00000037393,NMUR2,neuromedin U receptor 2,intracellular|plasma membrane|membrane|integral component of membrane|integral component of membrane|,reduction of food intake in response to dietary excess|calcium ion transport|chloride transport|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|grooming behavior|activation of phospholipase A2 activity by calcium-mediated signaling|inositol phosphate-mediated signaling|response to pain|arachidonic acid secretion|chloride transmembrane transport|,neuromedin U receptor activity|signal transducer activity|G-protein coupled receptor activity|intracellular calcium activated chloride channel activity|GTP binding|neuropeptide receptor activity|neuropeptide receptor activity|neuromedin U binding|,10,-0.2,1.02,10,-0.1,0.0805,-0.1,0.828,-0.828,0.347,0,0,-1.8,0.8
ENSMUSG00000036899,TRPV5,"transient receptor potential cation channel, subfamily V, member 5",intracellular|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|,transport|ion transport|calcium ion transport|cellular calcium ion homeostasis|protein tetramerization|transmembrane transport|calcium ion transport into cytosol|calcium ion transmembrane transport|,ion channel activity|calcium channel activity|calcium channel activity|protein binding|calmodulin binding|,10,-0.8,2.22,10,-0.1,0.0276,-0.2,0.827,-0.827,0.347,0,0,-2,0.4
ENSMUSG00000037418,BEST1,bestrophin 1,plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|chloride channel complex|,transport|ion transport|chloride transport|transepithelial chloride transport|detection of light stimulus involved in visual perception|regulation of calcium ion transport|chloride transmembrane transport|,chloride channel activity|,10,0.3,0.855,10,1,1.53,0.4,0.824,0.824,0.348,0,0,-0.5,2
ENSMUSG00000040724,KCNA2,"potassium voltage-gated channel, shaker-related subfamily, member 2",voltage-gated potassium channel complex|membrane|integral component of membrane|juxtaparanode region of axon|juxtaparanode region of axon|,transport|ion transport|potassium ion transport|optic nerve structural organization|regulation of ion transmembrane transport|protein oligomerization|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|protein binding|outward rectifier potassium channel activity|,10,0.1,0.0977,10,0.6,1.33,0.2,0.823,0.823,0.348,0,0,-0.5,2
ENSMUSG00000014747,ANKRD53,ankyrin repeat domain 53,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.47,10,0.2,0.147,-0.2,0.821,-0.821,0.349,0,0,-1.7,0.9
ENSMUSG00000048148,NWD1,NACHT and WD repeat domain containing 1,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,-0.1,0.269,10,0.4,1.05,0.3,0.821,0.821,0.349,0,0,-1.3,1.5
ENSMUSG00000022431,RIBC2,RIB43A domain with coiled-coils 2,nucleus|,biological_process|,molecular_function|,9,-0.2,0.729,9,0.3,2.25,0.2,0.819,0.819,0.349,0,0,-1.5,1.3
ENSMUSG00000038271,IFFO1,intermediate filament family orphan 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.4,1.56,0.2,0.813,0.813,0.351,0,0,-1.5,1.5
ENSMUSG00000020214,GLIPR1L2,GLI pathogenesis-related 1 like 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.5,1.57,10,0.1,0.171,0.2,0.813,0.813,0.351,0,0,-1.6,1.3
ENSMUSG00000042284,ITGA1,integrin alpha 1,acrosomal vesicle|focal adhesion|integrin complex|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|neuron projection|perikaryon|membrane raft|basal part of cell|extracellular vesicular exosome|,activation of MAPK activity|cell adhesion|integrin-mediated signaling pathway|negative regulation of cell proliferation|neutrophil chemotaxis|positive regulation of phosphoprotein phosphatase activity|negative regulation of epidermal growth factor receptor signaling pathway|vasodilation|positive regulation of neuron apoptotic process|cellular extravasation|neuron projection morphogenesis|cell chemotaxis|,receptor binding|protein binding|collagen binding|protein phosphatase binding|metal ion binding|,10,-0.2,0.559,10,0.5,3.06,0.4,0.812,0.812,0.351,0,0,-0.8,1.8
ENSMUSG00000048101,OLFR19,olfactory receptor 19,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,2.33,10,0,0,-0.2,0.807,-0.807,0.352,0,0,-1.7,0.9
ENSMUSG00000039131,GIPC2,"GIPC PDZ domain containing family, member 2",cytoplasm|extracellular vesicular exosome|,biological_process|,protein binding|,7,-0.1,0.176,8,0.5,1.52,0.2,0.805,0.805,0.353,0,0,-0.9,2
ENSMUSG00000048483,ZDHHC22,"zinc finger, DHHC-type containing 22",endoplasmic reticulum|Golgi apparatus|membrane|integral component of membrane|,protein palmitoylation|protein localization to plasma membrane|,"molecular_function|zinc ion binding|transferase activity|transferase activity, transferring acyl groups|protein-cysteine S-palmitoyltransferase activity|metal ion binding|",10,-0.3,1.42,10,0.3,1.15,-0.2,0.802,-0.802,0.354,0,0,-1.3,1.5
ENSMUSG00000031283,CHRDL1,chordin-like 1,extracellular region|,ossification|eye development|cell fate determination|multicellular organismal development|nervous system development|cell differentiation|neuron differentiation|negative regulation of BMP signaling pathway|compound eye development|,None,10,0,0,10,-0.3,1.36,-0.1,0.801,-0.801,0.354,0,0,-1.6,1.1
ENSMUSG00000060747,IFNL3,interferon lambda 3,extracellular region|extracellular space|,JAK-STAT cascade|innate immune response|positive regulation of immune response|defense response to virus|,receptor binding|cytokine activity|,10,-0.3,0.547,10,0.3,1.7,0.3,0.799,0.799,0.354,0,0,-1.3,1.8
ENSMUSG00000060735,RXFP3,relaxin family peptide receptor 3,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytokinesis|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled peptide receptor activity|,10,0.8,1.64,10,0.1,0.142,0.1,0.798,0.798,0.355,0,0,-0.7,2
ENSMUSG00000026344,LYPD1,Ly6/Plaur domain containing 1,plasma membrane|membrane|anchored component of membrane|,None,None,10,-0.2,1.75,10,0,0,-0.2,0.797,-0.797,0.355,0,0,-2,0.6
ENSMUSG00000079502,1700101E01RIK,RIKEN cDNA 1700101E01 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.5,2.62,0.2,0.794,0.794,0.356,0,0,-0.9,1.7
ENSMUSG00000027801,TM4SF4,transmembrane 4 superfamily member 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.2,0.701,9,0.2,0.157,0.2,0.789,0.789,0.357,0,0,-1.1,1.7
ENSMUSG00000031966,GLB1L3,"galactosidase, beta 1 like 3",cellular_component|,carbohydrate metabolic process|metabolic process|,"hydrolase activity, hydrolyzing O-glycosyl compounds|beta-galactosidase activity|lytic transglycosylase activity|mannosidase activity|mannosyl-oligosaccharide mannosidase activity|galactosidase activity|glucosidase activity|trehalase activity|fucosidase activity|hexosaminidase activity|amylase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|dextrin alpha-glucosidase activity|starch alpha-glucosidase activity|beta-glucanase activity|beta-6-sulfate-N-acetylglucosaminidase activity|glucan endo-1,4-beta-glucosidase activity|",10,0,0,10,-0.5,3.04,-0.4,0.785,-0.785,0.359,0,0,-1.8,0.8
ENSMUSG00000057092,FXYD3,FXYD domain-containing ion transport regulator 3,endoplasmic reticulum membrane|membrane|integral component of membrane|chloride channel complex|extracellular vesicular exosome|,transport|ion transport|chloride transport|regulation of catalytic activity|,ion channel activity|chloride channel activity|protein binding|ATPase binding|,10,0,0,10,-0.3,1.86,-0.2,0.784,-0.784,0.359,0,0,-1.8,0.7
ENSMUSG00000070907,IFNA7,interferon alpha 7,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|type I interferon receptor binding|,9,0,0,9,-0.4,1.63,-0.3,0.78,-0.78,0.36,0,0,-1.9,0.7
ENSMUSG00000046844,VAT1L,vesicle amine transport protein 1 homolog-like (T. californica),None,oxidation-reduction process|,zinc ion binding|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,-0.4,2.47,10,0,0,-0.2,0.778,-0.778,0.36,0,0,-1.7,0.9
ENSMUSG00000037716,CCDC33,coiled-coil domain containing 33,peroxisome|,spermatogenesis|,molecular_function|,10,-0.2,0.58,10,0.2,0.315,0.2,0.773,0.773,0.362,0,0,-1.4,1.3
ENSMUSG00000096753,FAM181A,"family with sequence similarity 181, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,1.23,-0.2,0.771,-0.771,0.362,0,0,-1.7,0.9
ENSMUSG00000026548,SLAMF9,SLAM family member 9,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|receptor activity|,10,1,2.66,10,-0.2,0.477,0.2,0.767,0.767,0.363,0,0,-0.6,2
ENSMUSG00000049939,LRRC4,leucine rich repeat containing 4,plasma membrane|membrane|integral component of membrane|cell junction|dendritic spine|neuron spine|synapse|postsynaptic membrane|excitatory synapse|,regulation of synapse organization|synapse organization|postsynaptic density protein 95 clustering|,protein binding|,10,0.2,1.11,10,0,0,0.2,0.767,0.767,0.363,0,0,-1.2,1.7
ENSMUSG00000018849,WWC1,"WW, C2 and coiled-coil domain containing 1",nucleus|cytoplasm|cytoplasm|cytosol|plasma membrane|membrane|ruffle membrane|cell projection|protein complex|perinuclear region of cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|cell migration|regulation of hippo signaling|negative regulation of hippo signaling|positive regulation of MAPK cascade|negative regulation of organ growth|","transcription coactivator activity|kinase binding|protein binding, bridging|protein complex scaffold|",10,-0.2,1.27,10,0.1,0.0671,-0.2,0.755,-0.755,0.366,0,0,-1.8,0.9
ENSMUSG00000008845,CD163,CD163 antigen,extracellular region|plasma membrane|membrane|integral component of membrane|,receptor-mediated endocytosis|acute-phase response|inflammatory response|,scavenger receptor activity|,9,-1.2,2.47,9,0,0,0.2,0.754,0.754,0.367,0,0,-2,0.9
ENSMUSG00000045267,TAS2R119,"taste receptor, type 2, member 119",cellular_component|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|detection of chemical stimulus involved in sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|bitter taste receptor activity|,10,-0.3,1.88,10,0.2,0.869,-0.2,0.753,-0.753,0.367,0,0,-1.7,1
ENSMUSG00000029862,CLCN1,chloride channel 1,membrane|integral component of membrane|chloride channel complex|sarcolemma|,transport|ion transport|chloride transport|chloride transport|neuronal action potential propagation|regulation of ion transmembrane transport|regulation of anion transport|transmembrane transport|chloride transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated chloride channel activity|chloride channel activity|adenyl nucleotide binding|,10,-0.3,0.637,10,-0.2,0.22,-0.2,0.751,-0.751,0.367,0,0,-2,0.5
ENSMUSG00000049362,OLFR173,olfactory receptor 173,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.4,0.886,10,0.1,0.276,0.2,0.75,0.75,0.368,0,0,-0.8,1.8
ENSMUSG00000043289,MEI4,"meiosis-specific, MEI4 homolog (S. cerevisiae)",lateral element|chromosome|,DNA recombination|meiotic nuclear division|synapsis|spermatogenesis|meiotic DNA double-strand break formation|oogenesis|,protein binding|,10,0.1,0.219,10,0.2,0.627,0.2,0.748,0.748,0.368,0,0,-1.2,1.6
ENSMUSG00000007805,TWIST2,twist basic helix-loop-helix transcription factor 2,nucleus|transcription factor complex|cytoplasm|,"negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|osteoblast differentiation|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter|multicellular organismal development|negative regulation of cell proliferation|positive regulation of keratinocyte proliferation|cell differentiation|negative regulation of tumor necrosis factor production|negative regulation of tumor necrosis factor production|negative regulation of apoptotic process|negative regulation of DNA binding|negative regulation of molecular function|negative regulation of myeloid cell differentiation|negative regulation of osteoblast differentiation|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-templated|embryonic cranial skeleton morphogenesis|face morphogenesis|cornea development in camera-type eye|",RNA polymerase II transcription factor binding transcription factor activity|DNA binding|chromatin binding|sequence-specific DNA binding transcription factor activity|protein binding|protein domain specific binding|protein dimerization activity|,10,-0.2,1.27,10,0,0,-0.1,0.746,-0.746,0.369,0,0,-1.8,1
ENSMUSG00000030472,CEACAM18,carcinoembryonic antigen-related cell adhesion molecule 18,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.929,10,0,0,0.1,0.745,0.745,0.369,0,0,-0.9,1.8
ENSMUSG00000028133,RWDD3,RWD domain containing 3,cellular_component|nucleus|cytoplasm|,negative regulation of NF-kappaB transcription factor activity|positive regulation of protein sumoylation|positive regulation of hypoxia-inducible factor-1alpha signaling pathway|,molecular_function|,10,-0.2,0.42,10,0.2,0.467,0.2,0.744,0.744,0.369,0,0,-1.2,1.4
ENSMUSG00000074505,FAT3,FAT tumor suppressor homolog 3 (Drosophila),plasma membrane|membrane|integral component of membrane|dendrite|,cell morphogenesis involved in differentiation|neuron migration|cell adhesion|homophilic cell adhesion|multicellular organismal development|retina layer formation|negative regulation of dendrite development|,calcium ion binding|,10,-0.2,0.499,10,-0.2,0.306,-0.2,0.739,-0.739,0.371,0,0,-1.8,0.7
ENSMUSG00000090843,GM17673,N/A,None,None,None,10,-0.1,0.35,10,0.4,0.853,0.4,0.736,0.736,0.371,0,0,-0.9,1.7
ENSMUSG00000010435,SPACA7,sperm acrosome associated 7,acrosomal vesicle|acrosomal vesicle|extracellular region|cell|,acrosome reaction|,molecular_function|,8,-0.2,0.888,8,0,0,-0.2,0.736,-0.736,0.371,0,0,-1.9,1
ENSMUSG00000047880,CXCR5,chemokine (C-X-C motif) receptor 5,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,chemotaxis|immune response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytokinesis|B cell activation|lymph node development|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|C-X-C chemokine receptor activity|,10,-0.3,2.02,10,0.2,0.218,-0.2,0.735,-0.735,0.372,0,0,-1.5,1.2
ENSMUSG00000063058,GM6406,predicted gene 6406,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.907,10,0.2,0.924,0.2,0.731,0.731,0.373,0,0,-1.6,1.3
ENSMUSG00000054204,FAM150B,"family with sequence similarity 150, member B",cellular_component|extracellular region|,biological_process|,molecular_function|,9,-0.3,1.36,9,0,0,-0.2,0.731,-0.731,0.373,0,0,-1.6,1.2
ENSMUSG00000021850,1700011H14RIK,RIKEN cDNA 1700011H14 gene,cellular_component|,biological_process|,molecular_function|,10,-0.4,1.57,10,0.4,2.34,0.3,0.727,0.727,0.374,0,0,-1.4,1.4
ENSMUSG00000043385,OLFR267,olfactory receptor 267,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0482,10,-0.4,1.79,-0.2,0.727,-0.727,0.374,0,0,-1.8,0.7
ENSMUSG00000028857,TMEM222,transmembrane protein 222,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.9,1.22,10,-0.1,0.259,-0.1,0.722,-0.722,0.375,0,0,-2,0.8
ENSMUSG00000047163,OLFR65,olfactory receptor 65,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.7,1.58,10,0.1,0.123,-0.4,0.722,-0.722,0.375,0,0,-2,0.6
ENSMUSG00000045148,OLFR1255,olfactory receptor 1255,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.148,10,-0.3,1,0.2,0.721,0.721,0.376,0,0,-1.2,1.5
ENSMUSG00000041293,GPR110,G protein-coupled receptor 110,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,-0.1,0.835,10,0,0,-0.1,0.721,-0.721,0.376,0,0,-1.9,0.8
ENSMUSG00000036381,P2RY14,"purinergic receptor P2Y, G-protein coupled, 14",plasma membrane|membrane|integral component of membrane|,immune response|signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled purinergic nucleotide receptor activity|,10,0,0,10,-0.3,1.06,-0.2,0.719,-0.719,0.376,0,0,-1.6,1
ENSMUSG00000029122,EVC,Ellis van Creveld gene syndrome,cytoplasm|cytoskeleton|plasma membrane|cilium|cilium|membrane|integral component of membrane|ciliary basal body|cell projection|,endochondral bone growth|smoothened signaling pathway|positive regulation of smoothened signaling pathway|,protein binding|,10,-0.1,0.0801,10,0.8,1.44,-0.2,0.717,-0.717,0.377,0,0,-1.1,1.9
ENSMUSG00000051455,GM1564,predicted gene 1564,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.691,10,0.3,1.2,0.2,0.711,0.711,0.378,0,0,-1.2,1.5
ENSMUSG00000013668,4933402N03RIK,RIKEN cDNA 4933402N03 gene,cellular_component|,biological_process|,molecular_function|,9,0.3,1.38,10,0.1,0.00318,0.2,0.709,0.709,0.379,0,0,-1.3,1.4
ENSMUSG00000041216,CLVS1,clavesin 1,intracellular|endosome|Golgi apparatus|trans-Golgi network|membrane|clathrin-coated vesicle|cytoplasmic vesicle|,transport|lysosome organization|,"transporter activity|lipid binding|phosphatidylinositol-3,5-bisphosphate binding|",10,-0.2,0.0566,10,0.8,2.14,0.2,0.707,0.707,0.379,0,0,-0.6,2
ENSMUSG00000021636,MARVELD2,MARVEL (membrane-associating) domain containing 2,cytoplasm|plasma membrane|tight junction|tight junction|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|cell junction|cytoplasmic vesicle|paranodal junction|Schmidt-Lanterman incisure|,sensory perception of sound|sensory perception of sound|cell-cell junction organization|cell-cell junction organization|establishment of endothelial barrier|tight junction assembly|,molecular_function|,10,-0.7,3.28,10,0.2,0.459,-0.6,0.707,-0.707,0.379,0,0,-1.8,1.4
ENSMUSG00000034112,ATP2C2,"ATPase, Ca++ transporting, type 2C, member 2",membrane|integral component of membrane|,transport|ion transport|cation transport|calcium ion transport|,nucleotide binding|calcium-transporting ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,0.6,0.791,10,0.2,0.206,0.3,0.704,0.704,0.381,0,0,-0.9,1.8
ENSMUSG00000045731,PNOC,prepronociceptin,extracellular region|,neuropeptide signaling pathway|synaptic transmission|,opioid peptide activity|,10,0.2,1.33,10,0,0,0.1,0.701,0.701,0.382,0,0,-1.3,1.5
ENSMUSG00000074384,AI429214,expressed sequence AI429214,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.24,10,1,0.929,-0.1,0.697,-0.697,0.383,0,0,-1.2,2
ENSMUSG00000038602,SLC35F1,"solute carrier family 35, member F1",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,-0.3,1.6,10,0,0,-0.2,0.696,-0.696,0.383,0,0,-1.6,1.1
ENSMUSG00000073971,OLFR554,olfactory receptor 554,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.816,10,0.1,0.378,-0.2,0.696,-0.696,0.383,0,0,-1.7,1.1
ENSMUSG00000050994,ADGB,androglobin,intracellular|cytoplasm|,proteolysis|oxygen transport|,calcium-dependent cysteine-type endopeptidase activity|iron ion binding|oxygen binding|heme binding|,10,-0.2,0.955,10,0.2,1.18,-0.1,0.691,-0.691,0.385,0,0,-1.7,1.1
ENSMUSG00000094146,GM10142,predicted gene 10142,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.2,0.696,10,0.1,0.0596,0.1,0.688,0.688,0.386,0,0,-1.2,1.6
ENSMUSG00000032338,HCN4,"hyperpolarization-activated, cyclic nucleotide-gated K+ 4",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|intrinsic component of plasma membrane|terminal bouton|,in utero embryonic development|regulation of heart rate|transport|ion transport|cation transport|potassium ion transport|sodium ion transport|regulation of heart contraction|ion transmembrane transport|regulation of ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|regulation of membrane potential|transmembrane transport|cellular response to cAMP|cellular response to cGMP|potassium ion transmembrane transport|potassium ion transmembrane transport|,nucleotide binding|ion channel activity|intracellular cAMP activated cation channel activity|intracellular cAMP activated cation channel activity|voltage-gated ion channel activity|voltage-gated sodium channel activity|voltage-gated potassium channel activity|voltage-gated potassium channel activity|potassium channel activity|sodium channel activity|protein binding|cAMP binding|identical protein binding|,10,0.2,0.766,10,0.1,0.135,0.1,0.687,0.687,0.386,0,0,-1.6,1.4
ENSMUSG00000058806,COL13A1,"collagen, type XIII, alpha 1",collagen trimer|plasma membrane|cell-cell junction|membrane|integral component of membrane|,ossification|cell adhesion|cell-matrix adhesion|multicellular organismal development|cell differentiation|,heparin binding|,10,-0.4,1.26,10,0,0,-0.2,0.687,-0.687,0.386,0,0,-1.9,0.7
ENSMUSG00000036412,ARSI,arylsulfatase i,cellular_component|extracellular region|endoplasmic reticulum|,metabolic process|,catalytic activity|sulfuric ester hydrolase activity|hydrolase activity|alkyl sulfatase activity|endosulfan hemisulfate sulfatase activity|endosulfan sulfate hydrolase activity|metal ion binding|,10,-0.1,0.335,10,-0.3,0.72,-0.1,0.681,-0.681,0.388,0,0,-1.6,1.2
ENSMUSG00000046031,FAM26F,"family with sequence similarity 26, member F",cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,-0.2,0.529,10,-0.1,0.346,-0.2,0.677,-0.677,0.389,0,0,-1.7,1
ENSMUSG00000040829,ZMYND15,"zinc finger, MYND-type containing 15",nucleus|cytoplasm|,"transcription, DNA-templated|regulation of transcription, DNA-templated|spermatogenesis|spermatid development|cell differentiation|negative regulation of transcription, DNA-templated|",histone deacetylase binding|metal ion binding|,10,0.2,0.637,10,0.2,0.096,0.2,0.674,0.674,0.39,0,0,-1,1.7
ENSMUSG00000044701,IL27,interleukin 27,extracellular region|extracellular space|,immune system process|inflammatory response|regulation of T cell proliferation|positive regulation of interferon-gamma biosynthetic process|innate immune response|regulation of T-helper 1 cell differentiation|,receptor binding|cytokine activity|protein binding|interleukin-27 receptor binding|,10,-0.3,0.581,10,-0.7,0.278,-0.2,0.667,-0.667,0.392,0,0,-1.9,1.1
ENSMUSG00000042190,CMKLR1,chemokine-like receptor 1,plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of macrophage chemotaxis|negative regulation of NF-kappaB transcription factor activity|negative regulation of interleukin-12 production|positive regulation of fat cell differentiation|regulation of calcium-mediated signaling|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|,10,0.3,1.43,10,0,0,0.2,0.666,0.666,0.392,0,0,-0.7,1.9
ENSMUSG00000041748,ACKR4,atypical chemokine receptor 4,endosome|plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|scavenger receptor activity|chemokine binding|,10,-0.1,0.684,10,-0.1,0.0383,-0.1,0.666,-0.666,0.392,0,0,-1.8,0.9
ENSMUSG00000049530,CLRN2,clarin 2,cellular_component|,biological_process|,molecular_function|,10,0.8,1.28,10,-0.2,0.274,0.1,0.664,0.664,0.393,0,0,-0.6,2
ENSMUSG00000052270,FPR2,formyl peptide receptor 2,plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|,signal transducer activity|receptor activity|G-protein coupled receptor activity|N-formyl peptide receptor activity|RAGE receptor binding|,10,0.3,1.81,10,0,0,0.2,0.662,0.662,0.393,0,0,-1,1.7
ENSMUSG00000051041,OLFML1,olfactomedin-like 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.913,10,0,0,-0.1,0.661,-0.661,0.393,0,0,-1.9,0.8
ENSMUSG00000075145,OLFR1155,olfactory receptor 1155,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.02,10,0.1,0.675,0.1,0.66,0.66,0.394,0,0,-1.3,1.4
ENSMUSG00000041134,CYYR1,cysteine and tyrosine-rich protein 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,1.3,10,0,0,-0.2,0.66,-0.66,0.394,0,0,-1.6,1.1
ENSMUSG00000054976,NYAP2,neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2,intracellular|,phosphatidylinositol 3-kinase signaling|neuron projection morphogenesis|,protein binding|,10,-0.2,1.28,10,0,0,-0.1,0.66,-0.66,0.394,0,0,-1.7,1
ENSMUSG00000044916,1700029I15RIK,RIKEN cDNA 1700029I15 gene,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.2,0.186,10,-0.3,0.565,-0.3,0.659,-0.659,0.394,0,0,-1.6,1.2
ENSMUSG00000038077,KCNA6,"potassium voltage-gated channel, shaker-related, subfamily, member 6",voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.2,0.109,10,-0.2,0.608,-0.2,0.659,-0.659,0.394,0,0,-1.7,1
ENSMUSG00000026748,PLXDC2,plexin domain containing 2,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,multicellular organismal development|,receptor activity|,10,-0.1,0.183,10,-0.4,0.869,-0.1,0.658,-0.658,0.394,0,0,-1.6,1.5
ENSMUSG00000073008,GPR174,G protein-coupled receptor 174,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,1.1,3.67,10,-0.2,0.573,1.1,0.657,0.657,0.395,0,0,-0.6,2
ENSMUSG00000044897,OLFR821,olfactory receptor 821,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,1,2.46,10,-0.1,0.049,0.2,0.653,0.653,0.396,0,0,-0.6,2
ENSMUSG00000027386,FBLN7,fibulin 7,extracellular region|proteinaceous extracellular matrix|extracellular vesicular exosome|,cell adhesion|,calcium ion binding|heparin binding|,10,0.3,2.06,10,0,0,0.2,0.651,0.651,0.396,0,0,-0.9,1.7
ENSMUSG00000046167,GLDN,gliomedin,collagen trimer|extracellular space|plasma membrane|membrane|integral component of membrane|,multicellular organismal development|nervous system development|cell differentiation|microvillus organization|heterotypic cell-cell adhesion|clustering of voltage-gated sodium channels|,protein binding|protein binding involved in heterotypic cell-cell adhesion|,10,-0.4,1.83,10,0,0,-0.1,0.65,-0.65,0.397,0,0,-1.7,0.9
ENSMUSG00000023978,PRPH2,peripherin 2,membrane|integral component of membrane|,cell adhesion|visual perception|retina development in camera-type eye|,None,10,0.3,2.16,10,0,0,0.2,0.647,0.647,0.398,0,0,-0.9,1.7
ENSMUSG00000026554,DCAF8,DDB1 and CUL4 associated factor 8,Cul4-RING E3 ubiquitin ligase complex|,biological_process|,molecular_function|,10,0.2,1.59,10,0,0,0.2,0.645,0.645,0.398,0,0,-1.1,1.6
ENSMUSG00000025236,ADPGK,ADP-dependent glucokinase,extracellular region|membrane|,carbohydrate metabolic process|glycolytic process|biological_process|phosphorylation|,"molecular_function|kinase activity|transferase activity|phosphotransferase activity, alcohol group as acceptor|ADP-specific glucokinase activity|metal ion binding|",10,0.3,2.35,10,-0.2,0.252,0.2,0.644,0.644,0.398,0,0,-1.3,1.4
ENSMUSG00000047992,FAM69C,"family with sequence similarity 69, member C",cellular_component|endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.9,1.63,10,0.1,0.141,0.2,0.643,0.643,0.399,0,0,-1.8,1.4
ENSMUSG00000016327,ATP1B4,"ATPase, (Na+)/K+ transporting, beta 4 polypeptide",chromatin|nucleus|nuclear envelope|nuclear inner membrane|sodium:potassium-exchanging ATPase complex|membrane|integral component of membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|transport|ion transport|potassium ion transport|sodium ion transport|",protein binding|,10,-0.4,1.24,10,-0.1,0.12,-0.3,0.642,-0.642,0.399,0,0,-1.5,1.3
ENSMUSG00000036466,MEGF11,multiple EGF-like-domains 11,cellular_component|plasma membrane|membrane|integral component of membrane|,retina layer formation|homotypic cell-cell adhesion|,molecular_function|,10,-0.2,0.948,10,0,0,-0.2,0.639,-0.639,0.4,0,0,-1.4,1.4
ENSMUSG00000017310,SPINT4,"serine protease inhibitor, Kunitz type 4",cellular_component|extracellular region|,biological_process|negative regulation of peptidase activity|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.1,0.468,10,0.1,0.227,0.1,0.637,0.637,0.401,0,0,-1.2,1.6
ENSMUSG00000079550,MPP4,"membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)",nucleus|cytoplasm|presynaptic membrane|intracellular membrane-bounded organelle|,protein localization to synapse|,receptor binding|,10,-0.2,0.935,10,-0.1,0.00277,-0.2,0.631,-0.631,0.402,0,0,-1.9,0.9
ENSMUSG00000067649,MAGEB18,"melanoma antigen family B, 18",cytoplasm|,biological_process|,molecular_function|,10,-0.3,1.4,10,0.4,1.63,-0.3,0.63,-0.63,0.403,0,0,-1.4,1.4
ENSMUSG00000042800,1700015E13RIK,RIKEN cDNA 1700015E13 gene,cellular_component|,biological_process|,molecular_function|,10,0.7,1.02,10,-0.1,0.135,-0.3,0.629,-0.629,0.403,0,0,-1.6,1.6
ENSMUSG00000062105,OLFR183,olfactory receptor 183,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.47,10,0.2,0.745,-0.2,0.628,-0.628,0.403,0,0,-1.6,1.1
ENSMUSG00000037167,SPACA5,sperm acrosome associated 5,cellular_component|extracellular region|,biological_process|metabolic process|cell wall macromolecule catabolic process|,"molecular_function|lysozyme activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.2,0.691,10,0.1,0.174,0.2,0.623,0.623,0.405,0,0,-1,1.7
ENSMUSG00000031290,LRCH2,leucine-rich repeats and calponin homology (CH) domain containing 2,cellular_component|,biological_process|,molecular_function|,10,-0.5,2.24,10,0.1,0.689,-0.2,0.622,-0.622,0.405,0,0,-1.8,0.8
ENSMUSG00000074575,KCNG1,"potassium voltage-gated channel, subfamily G, member 1",voltage-gated potassium channel complex|membrane|integral component of membrane|intracellular membrane-bounded organelle|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.2,0.513,10,0.1,0.264,0.1,0.62,0.62,0.406,0,0,-0.8,1.9
ENSMUSG00000095525,OLFR834,olfactory receptor 834,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.02,10,0,0,0.2,0.614,0.614,0.407,0,0,-1.2,1.5
ENSMUSG00000031517,GPM6A,glycoprotein m6a,plasma membrane|membrane|integral component of membrane|filopodium|cell projection|neuron projection|neuronal cell body|axonal growth cone|extracellular vesicular exosome|,neuron migration|neural retina development|nervous system development|synapse assembly|neuron projection morphogenesis|stem cell differentiation|positive regulation of filopodium assembly|calcium ion transmembrane transport|,calcium channel activity|,10,-0.3,0.862,10,-0.1,0.135,-0.2,0.614,-0.614,0.407,0,0,-1.5,1.3
ENSMUSG00000059069,OLFR749,olfactory receptor 749,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.192,10,0.5,1.58,-0.4,0.613,-0.613,0.408,0,0,-1.7,1.3
ENSMUSG00000045281,GPR20,G protein-coupled receptor 20,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,8,0.2,0.274,8,-0.4,0.698,-0.2,0.611,-0.611,0.408,0,0,-1.6,1.4
ENSMUSG00000026368,F13B,"coagulation factor XIII, beta subunit",cellular_component|extracellular region|,blood coagulation|hemostasis|biological_process|,molecular_function|,10,-0.1,0.355,10,-0.1,0.311,-0.1,0.609,-0.609,0.409,0,0,-1.2,1.7
ENSMUSG00000052726,KCNT2,"potassium channel, subfamily T, member 2",plasma membrane|voltage-gated potassium channel complex|,potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated potassium channel activity|potassium channel activity|calcium-activated potassium channel activity|,10,0.1,0.109,10,0.4,1.28,0.2,0.609,0.609,0.409,0,0,-1.1,1.6
ENSMUSG00000033854,KCNK10,"potassium channel, subfamily K, member 10",membrane|integral component of membrane|,transport|ion transport|potassium ion transmembrane transport|,potassium channel activity|,10,0.7,1.92,10,0.1,0.172,0.3,0.608,0.608,0.409,0,0,-0.6,1.9
ENSMUSG00000040298,BTBD16,BTB (POZ) domain containing 16,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.416,10,-0.3,0.282,-0.3,0.608,-0.608,0.409,0,0,-1.8,0.8
ENSMUSG00000090470,2410012M07RIK,RIKEN cDNA 2410012M07 gene,cellular_component|,biological_process|,molecular_function|,9,0.1,0.347,9,0.2,0.321,0.2,0.608,0.608,0.409,0,0,-1.1,1.7
ENSMUSG00000079481,NHSL2,NHS-like 2,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0816,10,-0.2,0.864,-0.1,0.608,-0.608,0.409,0,0,-1.7,1.1
ENSMUSG00000025370,CDH9,cadherin 9,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|,calcium ion binding|metal ion binding|,10,0.2,1.49,10,0,0,0.2,0.606,0.606,0.41,0,0,-1.4,1.4
ENSMUSG00000051095,OLFR986,olfactory receptor 986,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0077,10,0.2,0.676,0.1,0.604,0.604,0.411,0,0,-1.1,1.7
ENSMUSG00000031354,AMELX,"amelogenin, X-linked",extracellular region|proteinaceous extracellular matrix|basement membrane|cell surface|,cell adhesion|signal transduction|multicellular organismal development|cell proliferation|biomineral tissue development|tooth mineralization|,protein binding|growth factor activity|structural constituent of tooth enamel|identical protein binding|hydroxyapatite binding|,10,0.1,0.00989,10,0.5,1.38,0.2,0.601,0.601,0.412,0,0,-0.7,1.9
ENSMUSG00000046623,GJB4,"gap junction protein, beta 4",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,cell communication|sensory perception of smell|olfactory behavior|,None,10,0.8,1.57,10,0.2,0.234,0.3,0.601,0.601,0.412,0,0,-0.7,2
ENSMUSG00000034009,RXFP1,relaxin/insulin-like family peptide receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|parturition|cell differentiation|extracellular matrix organization|lung connective tissue development|nipple morphogenesis|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|hormone binding|metal ion binding|,10,0.2,0.829,10,0.8,0.509,0.1,0.601,0.601,0.412,0,0,-0.5,2
ENSMUSG00000046500,FAM19A4,"family with sequence similarity 19, member A4",cellular_component|extracellular region|,regulation of membrane potential|regulation of sensory perception of pain|,molecular_function|,10,-0.2,1.09,10,0,0,-0.2,0.6,-0.6,0.412,0,0,-2,0.7
ENSMUSG00000046845,IL1F10,"interleukin 1 family, member 10",cellular_component|extracellular region|extracellular space|,biological_process|,molecular_function|cytokine activity|interleukin-1 receptor binding|,10,0.1,0.0609,10,0.2,0.947,0.1,0.598,0.598,0.413,0,0,-1.4,1.4
ENSMUSG00000058725,GM11937,predicted gene 11937,cellular_component|,biological_process|,molecular_function|,10,0.1,0.475,10,0.6,0.237,0.1,0.597,0.597,0.413,0,0,-1,1.9
ENSMUSG00000034634,LY6D,"lymphocyte antigen 6 complex, locus D",plasma membrane|cell surface|membrane|anchored component of membrane|,None,None,10,0.7,0.652,10,0.1,0.38,0.2,0.596,0.596,0.413,0,0,-1,1.9
ENSMUSG00000060205,OLFR57,olfactory receptor 57,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.5,2.16,10,0,0,-0.1,0.593,-0.593,0.414,0,0,-1.9,0.7
ENSMUSG00000035849,KRT222,keratin 222,intermediate filament|,biological_process|,structural molecule activity|,10,-0.2,0.465,10,-0.1,0.19,-0.1,0.593,-0.593,0.414,0,0,-1.8,0.9
ENSMUSG00000027474,CCM2L,cerebral cavernous malformation 2-like,cellular_component|,cardiac atrium morphogenesis|ventricular trabecula myocardium morphogenesis|negative regulation of protein binding|negative regulation of homotypic cell-cell adhesion|wound healing|cardiac muscle tissue growth|positive regulation of fibroblast growth factor production|,protein binding|,10,-0.1,0.453,10,-0.1,0.194,-0.1,0.592,-0.592,0.415,0,0,-1.9,0.9
ENSMUSG00000047626,OLFR791,olfactory receptor 791,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.174,10,-1,1.99,-0.3,0.591,-0.591,0.415,0,0,-2,0.8
ENSMUSG00000036885,ARHGEF26,Rho guanine nucleotide exchange factor (GEF) 26,cellular_component|,endothelial cell morphogenesis|ruffle assembly|,molecular_function|,10,1,2.83,10,0.1,0.103,0.2,0.59,0.59,0.415,0,0,-0.4,2
ENSMUSG00000078938,SYCE3,synaptonemal complex central element protein 3,central element|nucleus|chromosome|,cell cycle|meiotic nuclear division|synaptonemal complex assembly|reciprocal meiotic recombination|spermatogenesis|positive regulation of apoptotic process|cell division|,protein binding|,10,0,0,10,0.7,0.897,0.1,0.587,0.587,0.417,0,0,-0.5,2
ENSMUSG00000029503,P2RX2,"purinergic receptor P2X, ligand-gated ion channel, 2",intracellular|integral component of nuclear inner membrane|plasma membrane|plasma membrane|integral component of plasma membrane|cell surface|postsynaptic density|membrane|integral component of membrane|apical plasma membrane|presynaptic membrane|neuronal cell body|terminal bouton|dendritic spine|receptor complex|,response to hypoxia|detection of hypoxic conditions in blood by carotid body chemoreceptor signaling|transport|ion transport|cation transport|cation transport|synaptic transmission|neuromuscular synaptic transmission|neuromuscular junction development|sensory perception of sound|sensory perception of sound|response to carbohydrate|response to organic substance|urinary bladder smooth muscle contraction|urinary bladder smooth muscle contraction|neuronal action potential|peristalsis|response to ATP|response to ATP|ion transmembrane transport|ion transmembrane transport|purinergic nucleotide receptor signaling pathway|behavioral response to pain|behavioral response to pain|skeletal muscle fiber development|sensory perception of taste|protein homooligomerization|protein heterooligomerization|,purinergic nucleotide receptor activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|extracellular ATP-gated cation channel activity|ion channel activity|copper ion binding|ATP binding|drug binding|zinc ion binding|ligand-gated ion channel activity|nickel cation binding|phosphatidylinositol binding|identical protein binding|mercury ion binding|cadmium ion binding|cobalt ion binding|,10,0.1,0.149,10,0.2,0.546,0.1,0.586,0.586,0.417,0,0,-1.2,1.7
ENSMUSG00000006777,KRT23,keratin 23,intermediate filament|,biological_process|,structural molecule activity|,10,0.1,0.0492,10,0.3,0.988,0.2,0.585,0.585,0.417,0,0,-0.9,1.8
ENSMUSG00000010142,TNFRSF13B,"tumor necrosis factor receptor superfamily, member 13b",integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,B cell homeostasis|hematopoietic progenitor cell differentiation|immune system process|negative regulation of B cell proliferation|,None,10,0.4,2.37,10,0,0,0.2,0.585,0.585,0.417,0,0,-0.8,1.8
ENSMUSG00000029309,SPARCL1,SPARC-like 1,extracellular region|proteinaceous extracellular matrix|extracellular space|synapse|extracellular vesicular exosome|,signal transduction|,calcium ion binding|metal ion binding|,10,-0.2,1.37,10,0,0,-0.2,0.583,-0.583,0.418,0,0,-1.6,1.1
ENSMUSG00000063867,OLFR1511,olfactory receptor 1511,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.2,2.07,0.2,0.582,0.582,0.418,0,0,-1.2,1.6
ENSMUSG00000052613,PCDH15,protocadherin 15,photoreceptor outer segment|photoreceptor outer segment|extracellular region|extracellular space|cytoplasm|plasma membrane|membrane|integral component of membrane|stereocilium|synapse|extracellular vesicular exosome|,startle response|morphogenesis of an epithelium|actin filament organization|cell adhesion|homophilic cell adhesion|visual perception|sensory perception of sound|sensory perception of sound|sensory perception of sound|locomotory behavior|adult walking behavior|adult locomotory behavior|nonmotile primary cilium assembly|multicellular organism growth|auditory receptor cell differentiation|photoreceptor cell maintenance|inner ear development|detection of mechanical stimulus involved in sensory perception of sound|sensory perception of light stimulus|equilibrioception|detection of mechanical stimulus involved in equilibrioception|righting reflex|auditory receptor cell stereocilium organization|auditory receptor cell stereocilium organization|,calcium ion binding|protein binding|,10,-0.4,1.18,10,0,0,-0.2,0.572,-0.572,0.422,0,0,-2,0.6
ENSMUSG00000075090,OLFR1234,olfactory receptor 1234,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.908,10,1,2.54,0.1,0.571,0.571,0.422,0,0,-0.7,2
ENSMUSG00000022986,KRT75,keratin 75,intracellular|intermediate filament|keratin filament|extracellular vesicular exosome|,hematopoietic progenitor cell differentiation|,structural molecule activity|,10,0.4,2.06,10,-1.2,1.41,0.2,0.564,0.564,0.424,0,0,-2,1.1
ENSMUSG00000050866,CLRN3,clarin 3,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,-0.4,1.74,-0.3,0.558,-0.558,0.426,0,0,-1.7,1
ENSMUSG00000059588,CALCRL,calcitonin receptor-like,lysosome|endosome|endoplasmic reticulum|plasma membrane|plasma membrane|membrane|integral component of membrane|,angiogenesis|cAMP biosynthetic process|calcium ion transport|regulation of muscle contraction|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|heart development|positive regulation of cell proliferation|protein transport|positive regulation of cAMP biosynthetic process|receptor internalization|positive regulation of smooth muscle cell proliferation|negative regulation of inflammatory response|cellular response to sucrose stimulus|,adrenomedullin receptor activity|calcitonin gene-related polypeptide receptor activity|signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcitonin receptor activity|protein transporter activity|,10,-0.3,0.769,10,0.3,1.21,0.2,0.556,0.556,0.427,0,0,-1.7,1
ENSMUSG00000043333,RHBDL2,"rhomboid, veinlet-like 2 (Drosophila)",plasma membrane|membrane|integral component of membrane|,proteolysis|,serine-type endopeptidase activity|serine-type endopeptidase activity|peptidase activity|serine-type peptidase activity|hydrolase activity|,10,-0.1,0.574,10,-0.1,0.0269,-0.1,0.553,-0.553,0.428,0,0,-1.8,0.9
ENSMUSG00000026415,FCAMR,"Fc receptor, IgA, IgM, high affinity",plasma membrane|membrane|integral component of membrane|,immune system process|immune response|signal transduction|,IgM binding|transmembrane signaling receptor activity|IgA binding|,10,0.2,0.752,10,0.1,0.0287,0.1,0.551,0.551,0.429,0,0,-1.3,1.6
ENSMUSG00000067049,UNC93A,unc-93 homolog A (C. elegans),plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.24,10,0,0,-0.1,0.548,-0.548,0.43,0,0,-1.8,0.8
ENSMUSG00000034912,MDGA2,MAM domain containing glycosylphosphatidylinositol anchor 2,plasma membrane|membrane|anchored component of membrane|,pattern specification process|,molecular_function|,10,0.1,0.498,10,0.1,0.0997,0.1,0.548,0.548,0.43,0,0,-1.3,1.6
ENSMUSG00000025774,CRISP4,cysteine-rich secretory protein 4,nucleus|,binding of sperm to zona pellucida|regulation of acrosome reaction|,calcium channel regulator activity|,10,0.1,0.063,10,-0.2,0.79,-0.2,0.547,-0.547,0.43,0,0,-1.1,1.8
ENSMUSG00000055088,OLFR354,olfactory receptor 354,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.42,10,0.1,0.19,0.1,0.547,0.547,0.43,0,0,-1.7,1.3
ENSMUSG00000053963,6330403A02RIK,RIKEN cDNA 6330403A02 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.311,10,-0.2,0.354,-0.1,0.543,-0.543,0.432,0,0,-1.7,1.1
ENSMUSG00000038702,DSEL,dermatan sulfate epimerase-like,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|sulfotransferase activity|carnitine racemase activity|isomerase activity|NADHX epimerase activity|NADPHX epimerase activity|,10,0.1,0.479,10,0.2,0.178,0.1,0.542,0.542,0.432,0,0,-1.3,1.6
ENSMUSG00000035860,CDHR3,cadherin-related family member 3,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|biological_process|,calcium ion binding|,10,0.1,0.325,10,-0.5,1.14,-0.4,0.541,-0.541,0.432,0,0,-1.8,0.9
ENSMUSG00000062760,1810041L15RIK,RIKEN cDNA 1810041L15 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.4,2.18,10,0,0,0.3,0.541,0.541,0.432,0,0,-0.8,1.8
ENSMUSG00000073916,OLFR669,olfactory receptor 669,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.644,10,0.1,0.0721,0.2,0.539,0.539,0.433,0,0,-1.3,1.5
ENSMUSG00000078670,FAM174B,"family with sequence similarity 174, member B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,4,-0.2,0.304,4,-0.2,0.284,-0.2,0.538,-0.538,0.433,0,0,-2,1.3
ENSMUSG00000033498,STRC,stereocilin,cilium|stereocilium bundle tip|cell projection|kinocilium|,sensory perception of sound|detection of mechanical stimulus involved in sensory perception of sound|auditory receptor cell stereocilium organization|,molecular_function|,10,-0.3,1.19,10,0,0,-0.1,0.535,-0.535,0.434,0,0,-1.7,1
ENSMUSG00000050640,TMEM150C,transmembrane protein 150C,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.2,1.13,-0.2,0.532,-0.532,0.435,0,0,-1.5,1.4
ENSMUSG00000022203,EFS,embryonal Fyn-associated substrate,None,cell adhesion|,SH3 domain binding|protein domain specific binding|,10,0.2,1.32,10,0,0,0.2,0.532,0.532,0.435,0,0,-1.2,1.6
ENSMUSG00000037683,ARMC3,armadillo repeat containing 3,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.4,2.38,10,-1.4,1.4,0.2,0.531,0.531,0.436,0,0,-2,1.2
ENSMUSG00000022455,WBP2NL,WBP2 N-terminal like,perinuclear theca|,egg activation|female pronucleus assembly|male pronucleus assembly|,WW domain binding|,10,0.1,0.456,10,0.2,0.291,0.2,0.53,0.53,0.436,0,0,-1.1,1.7
ENSMUSG00000047636,CDCP2,CUB domain containing protein 2,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.876,-0.2,0.528,-0.528,0.437,0,0,-1.8,0.9
ENSMUSG00000020019,NTN4,netrin 4,extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|,neuron remodeling|regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling|,laminin-1 binding|,10,-0.4,1.03,10,0,0,-0.4,0.524,-0.524,0.438,0,0,-1.9,1
ENSMUSG00000040490,LRFN2,leucine rich repeat and fibronectin type III domain containing 2,plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,None,protein binding|,10,-0.1,0.252,10,-0.1,0.319,-0.1,0.522,-0.522,0.439,0,0,-2,0.6
ENSMUSG00000069706,TAAR5,trace amine-associated receptor 5,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|sensory perception of chemical stimulus|behavior|mating behavior|social behavior|,trace-amine receptor activity|signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|trimethylamine receptor activity|trimethylamine receptor activity|,9,0.8,1.72,9,0.1,0.0647,0.4,0.522,0.522,0.439,0,0,-0.8,2
ENSMUSG00000051212,GPR183,G protein-coupled receptor 183,plasma membrane|membrane|integral component of membrane|,mature B cell differentiation involved in immune response|immune system process|humoral immune response|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of B cell proliferation|positive regulation of B cell proliferation|positive regulation of ERK1 and ERK2 cascade|,signal transducer activity|G-protein coupled receptor activity|oxysterol binding|oxysterol binding|,10,-0.4,0.795,10,0.1,0.438,0.1,0.522,0.522,0.439,0,0,-1.6,1.3
ENSMUSG00000023078,CXCL13,chemokine (C-X-C motif) ligand 13,extracellular region|extracellular space|,lymphocyte chemotaxis across high endothelial venule|chemotaxis|inflammatory response|immune response|cell surface receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|cell-cell signaling|positive regulation of T cell chemotaxis|activation of Rap GTPase activity|positive regulation of integrin activation|positive regulation of cell-cell adhesion mediated by integrin|B cell chemotaxis|B cell chemotaxis|endothelial cell chemotaxis to fibroblast growth factor|B cell chemotaxis across high endothelial venule|defense response to bacterium|lymph node development|lymph node development|chemokine-mediated signaling pathway|positive regulation of receptor activity|negative regulation of endothelial cell chemotaxis to fibroblast growth factor|,cytokine activity|chemokine activity|chemokine activity|heparin binding|fibroblast growth factor binding|CXCR5 chemokine receptor binding|CXCR5 chemokine receptor binding|CCR10 chemokine receptor binding|protein heterodimerization activity|receptor agonist activity|CXCR3 chemokine receptor binding|,10,-0.3,0.379,10,1.1,2.89,-0.1,0.52,-0.52,0.44,0,0,-0.7,2
ENSMUSG00000042254,CILP,"cartilage intermediate layer protein, nucleotide pyrophosphohydrolase",extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|,negative regulation of insulin-like growth factor receptor signaling pathway|,molecular_function|,10,0.2,1.02,10,0,0,0.1,0.52,0.52,0.44,0,0,-1,1.7
ENSMUSG00000028591,PRAMEF12,PRAME family member 12,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.03,10,-0.1,0.109,-0.3,0.517,-0.517,0.441,0,0,-1.7,1.2
ENSMUSG00000060560,CES4A,carboxylesterase 4A,cellular_component|extracellular region|,biological_process|,"phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|carboxylic ester hydrolase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,-0.2,1.22,10,0,0,-0.2,0.512,-0.512,0.443,0,0,-1.5,1.4
ENSMUSG00000046182,GSG1L,GSG1-like,plasma membrane|membrane|integral component of membrane|cell junction|asymmetric synapse|synapse|,regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,molecular_function|,10,0.2,0.579,10,-0.2,1.06,-0.1,0.511,-0.511,0.443,0,0,-1.5,1.3
ENSMUSG00000037686,ASPG,asparaginase homolog (S. cerevisiae),None,cellular amino acid metabolic process|asparagine metabolic process|lipid metabolic process|phospholipid metabolic process|lipid catabolic process|,1-alkyl-2-acetylglycerophosphocholine esterase activity|asparaginase activity|lysophospholipase activity|hydrolase activity|,10,-0.2,0.361,10,0.3,0.917,-0.1,0.51,-0.51,0.444,0,0,-1.5,1.3
ENSMUSG00000046634,PKD1L1,polycystic kidney disease 1 like 1,plasma membrane|cilium|membrane|integral component of membrane|nonmotile primary cilium|calcium channel complex|cell projection|,detection of nodal flow|transport|ion transport|calcium ion transport|detection of mechanical stimulus|left/right pattern formation|calcium ion transmembrane transport|left/right axis specification|,calcium channel activity|calcium channel activity|protein binding|,10,-0.2,0.916,10,0,0,-0.1,0.508,-0.508,0.445,0,0,-1.7,1.1
ENSMUSG00000079021,FLRT3,fibronectin leucine rich transmembrane protein 3,extracellular space|membrane|integral component of membrane|,axon guidance|negative chemotaxis|,protein binding|chemorepellent activity|,6,0.8,1.45,6,-0.1,0.108,-0.1,0.505,-0.505,0.446,0,0,-1.2,2
ENSMUSG00000070533,WFDC8,WAP four-disulfide core domain 8,cellular_component|extracellular region|membrane|integral component of membrane|,biological_process|negative regulation of peptidase activity|,molecular_function|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.1,0.304,10,-0.1,0.246,-0.1,0.503,-0.503,0.447,0,0,-1.6,1.6
ENSMUSG00000056600,OLFR90,olfactory receptor 90,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.504,10,-0.1,0.0446,-0.1,0.503,-0.503,0.447,0,0,-1.9,0.8
ENSMUSG00000074677,SIRPB1C,N/A,None,None,None,10,0.3,0.351,10,0.1,0.325,0.2,0.5,0.5,0.448,0,0,-0.6,1.9
ENSMUSG00000053964,LGALS4,"lectin, galactose binding, soluble 4",None,None,protein binding|carbohydrate binding|,10,-0.1,0.286,10,-0.3,0.528,-0.1,0.499,-0.499,0.448,0,0,-1.9,0.8
ENSMUSG00000024575,PDE6A,"phosphodiesterase 6A, cGMP-specific, rod, alpha",plasma membrane|membrane|,signal transduction|visual perception|GMP metabolic process|response to stimulus|cytosolic calcium ion homeostasis|retina development in camera-type eye|,"3',5'-cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|metal ion binding|3',5'-cyclic-GMP phosphodiesterase activity|",10,0.2,1.24,10,0,0,0.2,0.497,0.497,0.449,0,0,-1,1.7
ENSMUSG00000003476,CRHR2,corticotropin releasing hormone receptor 2,endoplasmic reticulum|rough endoplasmic reticulum|Golgi apparatus|Golgi apparatus|plasma membrane|cell surface|membrane|integral component of membrane|axon|dendrite|neuronal cell body|varicosity|perikaryon|axon terminus|cell body fiber|,actin filament organization|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|hormone-mediated signaling pathway|positive regulation of heart rate|positive regulation of gene expression|negative regulation of gene expression|negative regulation of norepinephrine secretion|positive regulation of serotonin secretion|negative regulation of angiogenesis|sensory perception of pain|positive regulation of cAMP metabolic process|negative regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|epithelial cell differentiation|positive regulation of interleukin-6 production|negative regulation of epinephrine secretion|positive regulation of stress-activated MAPK cascade|negative regulation of luteinizing hormone secretion|gastric motility|catecholamine biosynthetic process|positive regulation of cAMP-mediated signaling|negative regulation of cAMP-mediated signaling|positive regulation of blood pressure|negative regulation of follicle-stimulating hormone secretion|skeletal muscle tissue growth|positive regulation of NF-kappaB transcription factor activity|long-term synaptic potentiation|negative regulation of insulin secretion involved in cellular response to glucose stimulus|regulation of ERK1 and ERK2 cascade|cellular response to corticotropin-releasing hormone stimulus|negative regulation of calcium ion import|negative regulation of feeding behavior|negative regulation of defecation|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|hormone activity|protein binding|corticotrophin-releasing factor receptor activity|peptide hormone binding|corticotropin-releasing hormone receptor activity|,10,-0.4,1.74,10,0.1,0.367,-0.2,0.497,-0.497,0.449,0,0,-1.8,0.9
ENSMUSG00000024992,PDE6C,"phosphodiesterase 6C, cGMP specific, cone, alpha prime",plasma membrane|membrane|,"signal transduction|visual perception|phototransduction, visible light|retinal cone cell development|response to stimulus|sensory perception of light stimulus|","nucleotide binding|3',5'-cyclic-nucleotide phosphodiesterase activity|phosphoric diester hydrolase activity|hydrolase activity|cGMP binding|metal ion binding|3',5'-cyclic-GMP phosphodiesterase activity|",9,-1.1,1.82,9,-0.1,0.233,-0.1,0.496,-0.496,0.449,0,0,-2,0.6
ENSMUSG00000026971,ITGB6,integrin beta 6,integrin complex|external side of plasma membrane|membrane|integral component of membrane|receptor complex|extracellular vesicular exosome|,inflammatory response|cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|multicellular organismal development|,receptor activity|integrin binding|,10,-0.3,1.38,10,0,0,-0.2,0.495,-0.495,0.45,0,0,-1.7,1
ENSMUSG00000028813,CK137956,cDNA sequence CK137956,cellular_component|,biological_process|,molecular_function|,10,-0.2,1.19,10,0.1,0.382,-0.1,0.494,-0.494,0.45,0,0,-1.6,1.3
ENSMUSG00000060491,4930522H14RIK,RIKEN cDNA 4930522H14 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.218,10,-0.4,0.66,-0.2,0.493,-0.493,0.45,0,0,-1.9,0.7
ENSMUSG00000047084,NGRN,"neugrin, neurite outgrowth associated",extracellular region|nucleus|,multicellular organismal development|nervous system development|biological_process|cell differentiation|,poly(A) RNA binding|,10,0.3,1.68,10,-0.2,0.442,0.2,0.493,0.493,0.45,0,0,-1.5,1.4
ENSMUSG00000062064,SLC2A7,"solute carrier family 2 (facilitated glucose transporter), member 7",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,0,0,10,-0.3,0.863,-0.2,0.492,-0.492,0.451,0,0,-1.7,1
ENSMUSG00000046345,SMCO1,single-pass membrane protein with coiled-coil domains 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,1.87,10,0.2,0.322,0.2,0.491,0.491,0.451,0,0,-1.3,1.4
ENSMUSG00000019232,ETNPPL,ethanolamine phosphate phospholyase,cellular_component|mitochondrion|,biological_process|,catalytic activity|transaminase activity|transferase activity|lyase activity|pyridoxal phosphate binding|ethanolamine-phosphate phospho-lyase activity|,10,0.1,0.382,10,0.2,0.157,0.2,0.489,0.489,0.452,0,0,-1,1.7
ENSMUSG00000049073,OLFR985,olfactory receptor 985,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.593,10,-1.2,1.06,0.1,0.489,0.489,0.452,0,0,-2,1
ENSMUSG00000024076,VIT,vitrin,extracellular region|proteinaceous extracellular matrix|interstitial matrix|extracellular matrix|,positive regulation of cell-substrate adhesion|extracellular matrix organization|,glycosaminoglycan binding|,10,0.3,1.76,10,0,0,0.2,0.488,0.488,0.452,0,0,-0.9,1.8
ENSMUSG00000032719,SBSPON,"somatomedin B and thrombospondin, type 1 domain containing",extracellular region|proteinaceous extracellular matrix|extracellular matrix|,immune response|biological_process|,molecular_function|scavenger receptor activity|polysaccharide binding|,10,0.4,0.978,10,-0.2,0.445,0.2,0.487,0.487,0.453,0,0,-1,1.7
ENSMUSG00000051323,PCDH19,protocadherin 19,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|biological_process|,calcium ion binding|,10,-0.3,0.726,10,0.2,0.234,-0.1,0.487,-0.487,0.453,0,0,-1.5,1.2
ENSMUSG00000039099,WDR93,WD repeat domain 93,cellular_component|,biological_process|electron transport chain|,"molecular_function|oxidoreductase activity, acting on NAD(P)H|",10,0.1,0.453,10,0.1,0.0769,0.1,0.486,0.486,0.453,0,0,-1.1,1.7
ENSMUSG00000028427,AQP7,aquaporin 7,cytoplasm|plasma membrane|integral component of plasma membrane|cell-cell junction|membrane|integral component of membrane|ribonucleoprotein complex|brush border membrane|pore complex|,transport|ion transport|water transport|water transport|glycerol transport|glycerol transport|urea transport|carbohydrate transmembrane transport|transmembrane transport|renal water absorption|urea transmembrane transport|,transporter activity|water channel activity|water channel activity|glycerol channel activity|urea channel activity|porin activity|,10,-0.3,1.53,10,0,0,-0.2,0.486,-0.486,0.453,0,0,-2,0.6
ENSMUSG00000054134,UMODL1,uromodulin-like 1,extracellular region|extracellular space|plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,single fertilization|regulation of gene expression|regulation of apoptotic process|multicellular organismal reproductive process|adipose tissue development|cellular response to gonadotropin-releasing hormone|regulation of ovarian follicle development|,calcium ion binding|peptidase inhibitor activity|,10,-1.4,2.57,10,0,0,0.1,0.484,0.484,0.454,0,0,-2,0.7
ENSMUSG00000053862,SLC51B,"solute carrier family 51, beta subunit",plasma membrane|plasma membrane|membrane|integral component of membrane|protein complex|,transport|bile acid and bile salt transport|regulation of protein stability|positive regulation of protein glycosylation|positive regulation of protein exit from endoplasmic reticulum|positive regulation of protein targeting to membrane|,transporter activity|protein binding|protein heterodimerization activity|,10,0.1,0.0346,10,-0.2,1.01,-0.1,0.484,-0.484,0.454,0,0,-1.4,1.5
ENSMUSG00000095248,OLFR681,olfactory receptor 681,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.94,10,0.2,0.538,-0.1,0.483,-0.483,0.454,0,0,-1.6,1.1
ENSMUSG00000052229,GPR17,G protein-coupled receptor 17,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,9,0.6,1.29,9,-0.2,0.34,-0.1,0.482,-0.482,0.455,0,0,-1.2,1.8
ENSMUSG00000001741,IL16,interleukin 16,extracellular region|extracellular space|intracellular|nucleus|cytoplasm|plasma membrane|,"transcription, DNA-templated|regulation of transcription, DNA-templated|chemotaxis|leukocyte chemotaxis|induction of positive chemotaxis|",cytokine activity|protein binding|,10,-0.2,0.74,10,0,0,-0.1,0.481,-0.481,0.455,0,0,-1.7,1.1
ENSMUSG00000095719,A830018L16RIK,RIKEN cDNA A830018L16 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.287,10,-0.4,0.349,-0.1,0.479,-0.479,0.456,0,0,-1.9,0.7
ENSMUSG00000073110,OLFR444,olfactory receptor 444,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.845,10,0,0,-0.1,0.478,-0.478,0.456,0,0,-1.8,1.1
ENSMUSG00000036944,TMEM71,transmembrane protein 71,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.3,0.971,10,0.1,0.024,0.2,0.478,0.478,0.456,0,0,-1.6,1.3
ENSMUSG00000025790,SLCO3A1,"solute carrier organic anion transporter family, member 3a1",plasma membrane|integral component of plasma membrane|basal plasma membrane|cell surface|membrane|integral component of membrane|apical plasma membrane|,transport|ion transport|oligopeptide transport|organic anion transport|prostaglandin transport|ion transmembrane transport|,transporter activity|organic anion transmembrane transporter activity|oligopeptide transporter activity|,10,-0.1,0.447,10,-0.1,0.0718,-0.1,0.476,-0.476,0.457,0,0,-1.5,1.3
ENSMUSG00000042436,MFAP4,microfibrillar-associated protein 4,microfibril|extracellular region|proteinaceous extracellular matrix|extracellular matrix|extracellular vesicular exosome|elastic fiber|,cell adhesion|UV protection|regulation of collagen metabolic process|extracellular fibril organization|elastic fiber assembly|cellular response to UV-B|,None,10,0.2,1.2,10,0,0,0.1,0.476,0.476,0.457,0,0,-0.7,2
ENSMUSG00000050028,OLFR745,olfactory receptor 745,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.311,10,0.1,0.891,0.1,0.474,0.474,0.458,0,0,-1.5,1.4
ENSMUSG00000055033,OLFR420,olfactory receptor 420,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.8,0.00425,10,-0.3,1.11,-0.4,0.473,-0.473,0.458,0,0,-2,0.7
ENSMUSG00000062157,IFNLR1,interferon lambda receptor 1,membrane|integral component of membrane|interleukin-28 receptor complex|,mucosal immune response|cytokine-mediated signaling pathway|regulation of defense response to virus by host|defense response to virus|defense response to virus|,cytokine receptor activity|,10,-0.1,0.113,10,-0.1,0.404,-0.1,0.473,-0.473,0.458,0,0,-1.5,1.4
ENSMUSG00000060756,KRTAP2-4,keratin associated protein 2-4,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.822,0.1,0.471,0.471,0.459,0,0,-1.2,1.6
ENSMUSG00000024409,PSORS1C2,psoriasis susceptibility 1 candidate 2 (human),cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.7,2,10,0,0,0.3,0.47,0.47,0.459,0,0,-0.7,2
ENSMUSG00000070421,OLFR658,olfactory receptor 658,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.2,1.06,0.1,0.467,0.467,0.461,0,0,-1.1,1.7
ENSMUSG00000070504,FCRL6,Fc receptor-like 6,external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,biological_process|,protein phosphatase binding|,10,-0.1,0.19,10,-0.7,0.868,-0.1,0.464,-0.464,0.462,0,0,-2,0.6
ENSMUSG00000039578,CCSER1,coiled-coil serine rich 1,cellular_component|,biological_process|,molecular_function|,10,-0.3,2.03,10,0,0,-0.2,0.462,-0.462,0.463,0,0,-1.6,1.1
ENSMUSG00000031661,NKD1,naked cuticle 1 homolog (Drosophila),protein phosphatase type 2A complex|cytoplasm|plasma membrane|membrane|,"multicellular organismal development|spermatogenesis|Wnt signaling pathway|cell differentiation|negative regulation of Wnt signaling pathway|positive regulation of protein catabolic process|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|positive regulation of non-canonical Wnt signaling pathway via JNK cascade|negative regulation of convergent extension involved in axis elongation|positive regulation of Wnt signaling pathway, planar cell polarity pathway|",calcium ion binding|protein binding|PDZ domain binding|metal ion binding|,10,0,0,10,-0.6,2.87,-0.5,0.461,-0.461,0.463,0,0,-1.9,0.6
ENSMUSG00000025739,GNG13,"guanine nucleotide binding protein (G protein), gamma 13",heterotrimeric G-protein complex|plasma membrane|membrane|,signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|sensory perception of taste|,signal transducer activity|G-protein beta-subunit binding|,10,0,0,10,0.3,1.54,0.1,0.459,0.459,0.464,0,0,-0.9,1.8
ENSMUSG00000028584,LRRC38,leucine rich repeat containing 38,cellular_component|plasma membrane|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,-0.3,2.52,10,0,0,-0.3,0.458,-0.458,0.464,0,0,-2,0.6
ENSMUSG00000001995,SIPA1L2,signal-induced proliferation-associated 1 like 2,cellular_component|,biological_process|regulation of small GTPase mediated signal transduction|,molecular_function|GTPase activator activity|,10,0.4,1.1,10,0,0,-0.1,0.457,-0.457,0.465,0,0,-1.5,1.4
ENSMUSG00000040264,GBP5,guanylate binding protein 5,cytoplasm|membrane|membrane|cytoplasmic vesicle|,cellular response to interferon-gamma|,nucleotide binding|GTPase activity|GTP binding|identical protein binding|,9,0.1,0.157,9,0.9,1.84,0.2,0.457,0.457,0.465,0,0,-0.6,2
ENSMUSG00000054406,OLFR411,olfactory receptor 411,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,1.1,3.47,10,0,0,1.1,0.456,0.456,0.465,0,0,-0.6,2
ENSMUSG00000093825,OLFR723,olfactory receptor 723,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.3,1.17,0.1,0.454,0.454,0.466,0,0,-1.1,1.7
ENSMUSG00000040329,IL7,interleukin 7,extracellular region|extracellular space|,T cell lineage commitment|immune response|regulation of gene expression|regulation of gene expression|positive regulation of B cell proliferation|positive regulation of B cell proliferation|negative regulation of catalytic activity|bone resorption|positive regulation of T cell differentiation|positive regulation of organ growth|positive regulation of organ growth|homeostasis of number of cells within a tissue|negative regulation of extrinsic apoptotic signaling pathway|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,cytokine activity|cytokine receptor binding|interleukin-7 receptor binding|growth factor activity|,7,0.2,0.376,7,0.4,0.265,0.2,0.453,0.453,0.467,0,0,-1,2
ENSMUSG00000044025,OLFR790,olfactory receptor 790,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.292,10,0.1,0.202,0.1,0.452,0.452,0.467,0,0,-0.9,1.9
ENSMUSG00000037689,TMEM247,transmembrane protein 247,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.7,1.37,0.1,0.451,0.451,0.467,0,0,-0.9,1.9
ENSMUSG00000059203,IL1RAPL2,interleukin 1 receptor accessory protein-like 2,membrane|integral component of membrane|,signal transduction|,"interleukin-1, Type II, blocking receptor activity|",10,-0.3,0.743,10,-0.1,0.0196,-0.2,0.451,-0.451,0.467,0,0,-1.8,0.9
ENSMUSG00000032355,MLIP,muscular LMNA-interacting protein,nucleus|nuclear envelope|PML body|nuclear lumen|,biological_process|,molecular_function|,10,-0.4,1.78,10,0.1,0.018,-0.2,0.45,-0.45,0.468,0,0,-1.9,0.8
ENSMUSG00000050128,OLFR1023,olfactory receptor 1023,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,0,0,9,-0.5,1.89,-0.4,0.449,-0.449,0.468,0,0,-2,0.7
ENSMUSG00000015452,AGER,advanced glycosylation end product-specific receptor,extracellular space|cytoplasm|cytosol|plasma membrane|basal plasma membrane|cell surface|membrane|integral component of membrane|axon|neuronal cell body|,negative regulation of protein phosphorylation|positive regulation of protein phosphorylation|negative regulation of endothelial cell proliferation|inflammatory response|negative regulation of cell adhesion|JAK-STAT cascade|positive regulation of autophagy|negative regulation of endothelial cell migration|positive regulation of gene expression|positive regulation of epithelial to mesenchymal transition|positive regulation of fibroblast migration|positive regulation of smooth muscle cell migration|positive regulation of cell migration|neuron projection development|negative regulation of collagen biosynthetic process|positive regulation of apoptotic process|positive regulation of neuron apoptotic process|positive regulation of fibroblast proliferation|positive regulation of smooth muscle cell proliferation|regulation of inflammatory response|positive regulation of inflammatory response|induction of positive chemotaxis|positive regulation of NF-kappaB transcription factor activity|calcium ion homeostasis|positive regulation of potassium ion transmembrane transporter activity|positive regulation of neuron death|positive regulation of endothelial cell apoptotic process|positive regulation of reactive oxygen species metabolic process|positive regulation of type B pancreatic cell apoptotic process|,protein binding|identical protein binding|S100 protein binding|S100 protein binding|advanced glycation end-product receptor activity|high mobility group box 1 binding|,10,0.1,0.271,10,0.1,0.221,0.1,0.449,0.449,0.468,0,0,-1.4,1.5
ENSMUSG00000020928,HIGD1B,"HIG1 domain family, member 1B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.3,0.833,0.1,0.449,0.449,0.468,0,0,-0.8,2
ENSMUSG00000061080,LSAMP,limbic system-associated membrane protein,plasma membrane|membrane|anchored component of membrane|,cell adhesion|locomotory exploration behavior|,None,10,0.3,1.14,10,-0.2,0.888,-0.2,0.449,-0.449,0.468,0,0,-1.3,1.4
ENSMUSG00000032125,ROBO4,roundabout homolog 4 (Drosophila),external side of plasma membrane|integral component of membrane|extracellular vesicular exosome|,angiogenesis|multicellular organismal development|cell differentiation|negative regulation of cell migration|,receptor activity|protein binding|,9,-0.4,1.99,9,0.3,0.26,-0.3,0.444,-0.444,0.47,0,0,-2,0.8
ENSMUSG00000035831,KRT25,keratin 25,cytoplasm|intermediate filament|,aging|hair follicle morphogenesis|hair cycle|intermediate filament organization|,structural molecule activity|protein binding|,10,0.4,0.88,10,-0.2,0.212,0.2,0.444,0.444,0.47,0,0,-1.3,1.5
ENSMUSG00000073811,IFNA12,interferon alpha 12,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,9,0.2,0.66,9,-1.5,3.25,-0.1,0.444,-0.444,0.47,0,0,-3,0.6
ENSMUSG00000070695,CNTNAP5A,contactin associated protein-like 5A,membrane|integral component of membrane|,proteolysis|cell adhesion|,aspartic-type endopeptidase activity|,10,0.8,0.536,10,-1.4,2,-0.1,0.441,-0.441,0.471,0,0,-3,1.2
ENSMUSG00000009216,FAM163B,"family with sequence similarity 163, member B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.367,10,-0.8,0.355,-0.2,0.441,-0.441,0.471,0,0,-2,0.6
ENSMUSG00000092518,FAM71E2,"family with sequence similarity 71, member E2",cellular_component|,biological_process|,molecular_function|,10,0.1,0.481,10,-0.5,1.6,0.2,0.44,0.44,0.472,0,0,-1.7,1.1
ENSMUSG00000032062,2310030G06RIK,RIKEN cDNA 2310030G06 gene,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,1.33,10,0,0,0.1,0.439,0.439,0.472,0,0,-1.1,1.7
ENSMUSG00000043243,FAM129C,"family with sequence similarity 129, member C",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.627,-0.1,0.438,-0.438,0.473,0,0,-1.8,1
ENSMUSG00000051917,TAS2R144,"taste receptor, type 2, member 144",membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|bitter taste receptor activity|,10,-0.2,1.12,10,0,0,-0.2,0.437,-0.437,0.473,0,0,-1.5,1.2
ENSMUSG00000075175,OLFR1086,olfactory receptor 1086,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.56,10,0,0,0.2,0.436,0.436,0.473,0,0,-1.2,1.6
ENSMUSG00000075166,OLFR1104,olfactory receptor 1104,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.236,10,0.2,0.946,0.2,0.435,0.435,0.474,0,0,-1.5,1.3
ENSMUSG00000001494,SOST,sclerostin,extracellular region|proteinaceous extracellular matrix|extracellular space|Golgi apparatus|extracellular matrix|,"ossification|Wnt signaling pathway|negative regulation of Wnt signaling pathway|negative regulation of ossification|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|negative regulation of protein complex assembly|positive regulation of transcription, DNA-templated|cellular response to parathyroid hormone stimulus|negative regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification|",protein binding|transcription factor binding|heparin binding|,10,-0.2,0.724,10,0,0,-0.1,0.43,-0.43,0.476,0,0,-1.7,1.1
ENSMUSG00000053675,TGM5,transglutaminase 5,cellular_component|cytoplasm|,peptide cross-linking|,"molecular_function|protein-glutamine gamma-glutamyltransferase activity|transferase activity|transferase activity, transferring acyl groups|metal ion binding|",10,-0.1,0.341,10,-0.1,0.13,-0.1,0.43,-0.43,0.476,0,0,-1.7,1.1
ENSMUSG00000066058,CLDN19,claudin 19,nucleus|cytoplasm|plasma membrane|tight junction|tight junction|membrane|integral component of membrane|basolateral plasma membrane|cell junction|apical junction complex|,neuronal action potential propagation|apical junction assembly|,structural molecule activity|,10,0,0,10,-0.2,0.806,-0.1,0.43,-0.43,0.476,0,0,-1.6,1.3
ENSMUSG00000029307,DMP1,dentin matrix protein 1,extracellular region|proteinaceous extracellular matrix|nucleus|nucleolus|cytoplasm|intracellular membrane-bounded organelle|,ossification|positive regulation of cell-substrate adhesion|extracellular matrix organization|biomineral tissue development|,extracellular matrix binding|,10,1,2.01,10,-0.2,0.736,-0.1,0.43,-0.43,0.476,0,0,-0.8,2
ENSMUSG00000033033,CALHM2,calcium homeostasis modulator 2,cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,0.1,0.352,10,0.1,0.118,0.1,0.43,0.43,0.476,0,0,-1.2,1.7
ENSMUSG00000029659,MEDAG,mesenteric estrogen dependent adipogenesis,cytoplasm|cytoplasm|,positive regulation of fat cell differentiation|,molecular_function|,10,0.3,0.0618,10,0.7,0.983,0.1,0.429,0.429,0.477,0,0,-0.6,2
ENSMUSG00000048965,MRGPRE,"MAS-related GPR, member E",cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.3,1.42,10,0,0,-0.2,0.429,-0.429,0.477,0,0,-1.3,1.4
ENSMUSG00000039097,RLN1,relaxin 1,extracellular region|,adenylate cyclase-modulating G-protein coupled receptor signaling pathway|regulation of nitric oxide mediated signal transduction|regulation of nitric oxide mediated signal transduction|developmental growth|prostate gland growth|,receptor binding|hormone activity|,9,-0.2,0.624,9,-0.1,0.0583,-0.2,0.427,-0.427,0.477,0,0,-1.5,1.5
ENSMUSG00000047712,UST,uronyl-2-sulfotransferase,Golgi apparatus|membrane|integral component of membrane|,None,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0.1,0.0769,10,0.2,0.392,0.2,0.426,0.426,0.478,0,0,-1,1.8
ENSMUSG00000030887,PDZD9,PDZ domain containing 9,cellular_component|,biological_process|,molecular_function|,10,0.1,0.685,10,0,0,0.1,0.424,0.424,0.479,0,0,-0.8,2
ENSMUSG00000066239,OLFR519,olfactory receptor 519,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,0,0,9,-0.3,0.75,-0.2,0.423,-0.423,0.479,0,0,-1.7,1.1
ENSMUSG00000024552,SLC14A2,"solute carrier family 14 (urea transporter), member 2",plasma membrane|membrane|integral component of membrane|,urea transport|urea transmembrane transport|,urea transmembrane transporter activity|urea transmembrane transporter activity|cell adhesion molecule binding|,10,0.2,0.327,10,0.1,0.203,0.1,0.421,0.421,0.48,0,0,-1,1.8
ENSMUSG00000022388,TTLL8,"tubulin tyrosine ligase-like family, member 8",cytoplasm|cytoskeleton|microtubule|cilium|axoneme|microtubule cytoskeleton|cell projection|,cellular protein modification process|protein polyglycylation|cilium assembly|cilium assembly|,"UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity|ligase activity|ribosomal S6-glutamic acid ligase activity|coenzyme F420-0 gamma-glutamyl ligase activity|coenzyme F420-2 alpha-glutamyl ligase activity|protein-glycine ligase activity|protein-glycine ligase activity, initiating|protein-glycine ligase activity, elongating|tubulin-glycine ligase activity|protein-glutamic acid ligase activity|tubulin-glutamic acid ligase activity|",10,-0.2,0.626,10,0,0,-0.1,0.42,-0.42,0.481,0,0,-1.7,1.2
ENSMUSG00000095654,PLSCR5,"phospholipid scramblase family, member 5",cellular_component|,biological_process|,molecular_function|,10,0.7,1.49,10,0,0,0.3,0.42,0.42,0.481,0,0,-0.7,1.9
ENSMUSG00000026073,IL1R2,"interleukin 1 receptor, type II",extracellular region|plasma membrane|membrane|integral component of membrane|,None,"interleukin-1 receptor activity|interleukin-1, Type II, blocking receptor activity|",10,-0.1,0.0804,10,-0.4,0.839,-0.2,0.419,-0.419,0.481,0,0,-1.7,1.1
ENSMUSG00000027225,DUOXA2,dual oxidase maturation factor 2,cellular_component|endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,transport|protein transport|hydrogen peroxide metabolic process|regulation of inflammatory response|regulation of thyroid hormone generation|,molecular_function|,10,-0.2,0.355,10,-0.1,0.164,-0.1,0.419,-0.419,0.481,0,0,-1.7,1.1
ENSMUSG00000033207,MAMDC2,MAM domain containing 2,extracellular region|proteinaceous extracellular matrix|interstitial matrix|endoplasmic reticulum|membrane|extracellular matrix|,peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan|,glycosaminoglycan binding|,10,-0.1,0.0727,10,0.4,1.64,0.2,0.418,0.418,0.481,0,0,-1,1.7
ENSMUSG00000069718,GM11563,predicted gene 11563,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.2,1.05,10,-0.1,0.246,0.1,0.418,0.418,0.481,0,0,-1.3,1.4
ENSMUSG00000063529,STMND1,stathmin domain containing 1,cellular_component|,biological_process|regulation of microtubule polymerization or depolymerization|,molecular_function|,10,-0.1,0.161,10,-0.2,0.321,-0.1,0.417,-0.417,0.482,0,0,-1.7,1.1
ENSMUSG00000035298,KLHL35,kelch-like 35,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.203,10,0.6,0.459,-0.1,0.417,-0.417,0.482,0,0,-0.8,1.8
ENSMUSG00000043719,COL6A6,"collagen, type VI, alpha 6",extracellular region|proteinaceous extracellular matrix|collagen trimer|extracellular matrix|,cell adhesion|,molecular_function|,10,-0.3,0.826,10,-0.1,0.0629,-0.3,0.417,-0.417,0.482,0,0,-2,0.6
ENSMUSG00000055235,WDR86,WD repeat domain 86,cellular_component|,biological_process|,molecular_function|,10,-0.3,1.55,10,0.4,1.47,-0.2,0.416,-0.416,0.482,0,0,-1.3,1.5
ENSMUSG00000020704,ASIC2,acid-sensing (proton-gated) ion channel 2,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|neuron projection|neuronal cell body|dendritic spine|synapse|,regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback|transport|ion transport|cation transport|cation transport|sodium ion transport|sodium ion transport|phototransduction|sensory perception of sound|response to mechanical stimulus|response to acidity|response to acidity|regulation of gene expression|regulation of vasoconstriction|regulation of blood coagulation|ion transmembrane transport|ion transmembrane transport|regulation of ion transmembrane transport|protein localization to synapse|sodium ion transmembrane transport|sodium ion transmembrane transport|regulation of membrane potential|negative regulation of apoptotic process|sensory perception of sour taste|detection of mechanical stimulus involved in sensory perception|positive regulation of synapse assembly|cellular response to acid|cellular response to acidity|positive regulation of cation channel activity|,ion channel activity|ion channel activity|voltage-gated sodium channel activity|cation channel activity|cation channel activity|sodium channel activity|protein binding|ligand-gated sodium channel activity|ion gated channel activity|ion gated channel activity|,10,0.2,0.687,10,0,0,0.1,0.414,0.414,0.483,0,0,-1,1.8
ENSMUSG00000043313,PCDHB19,protocadherin beta 19,plasma membrane|membrane|integral component of membrane|,cell adhesion|,None,10,-1.4,2.85,10,0.1,0.193,0.1,0.413,0.413,0.484,0,0,-3,0.9
ENSMUSG00000074378,BSPH1,binder of sperm protein homolog 1,extracellular region|extracellular space|cell surface|,single fertilization|sperm capacitation|,heparin binding|,10,0.1,0.144,10,0.2,0.437,0.1,0.412,0.412,0.484,0,0,-1.2,1.7
ENSMUSG00000042269,FAM92B,"family with sequence similarity 92, member B",cellular_component|,biological_process|,molecular_function|,10,0.1,0.238,10,0.1,0.213,0.1,0.412,0.412,0.484,0,0,-1.3,1.6
ENSMUSG00000055214,PLD5,"phospholipase D family, member 5",cellular_component|membrane|integral component of membrane|,biological_process|metabolic process|,molecular_function|catalytic activity|,10,0.5,2.07,10,-0.2,0.755,0.1,0.412,0.412,0.484,0,0,-1,1.7
ENSMUSG00000045201,LRRC3B,leucine rich repeat containing 3B,membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,0.937,10,0,0,-0.1,0.411,-0.411,0.484,0,0,-1.9,0.8
ENSMUSG00000027788,OTOL1,otolin 1 homolog (zebrafish),cellular_component|extracellular region|collagen trimer|,biological_process|,molecular_function|,10,0.1,0.118,10,-0.2,0.547,-0.1,0.411,-0.411,0.484,0,0,-1.2,1.6
ENSMUSG00000054690,EMCN,endomucin,membrane|integral component of membrane|integral component of membrane|,None,None,10,-0.2,0.694,10,0,0,0.2,0.41,0.41,0.485,0,0,-0.9,1.8
ENSMUSG00000070532,1700084C01RIK,RIKEN cDNA 1700084C01 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.726,10,0,0,0.1,0.409,0.409,0.485,0,0,-1.4,1.5
ENSMUSG00000070708,GTSF1L,gametocyte specific factor 1-like,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.4,1.17,10,0,0,0.4,0.409,0.409,0.485,0,0,-0.7,1.9
ENSMUSG00000017400,STAC2,SH3 and cysteine rich domain 2,cellular_component|,biological_process|intracellular signal transduction|,molecular_function|metal ion binding|,10,-0.2,1.25,10,0.2,0.974,0.1,0.408,0.408,0.486,0,0,-1.4,1.4
ENSMUSG00000066607,6030419C18RIK,RIKEN cDNA 6030419C18 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,1.23,10,-0.1,0.287,0.2,0.406,0.406,0.487,0,0,-0.8,1.9
ENSMUSG00000053194,CIB4,calcium and integrin binding family member 4,cellular_component|,biological_process|,calcium ion binding|metal ion binding|,10,-0.2,1.12,10,0.1,0.203,-0.1,0.399,-0.399,0.49,0,0,-1.5,1.5
ENSMUSG00000030116,MFAP5,microfibrillar associated protein 5,microfibril|extracellular region|proteinaceous extracellular matrix|extracellular matrix|,extracellular fibril organization|,extracellular matrix constituent conferring elasticity|,10,0.1,0.257,10,0.1,0.175,0.1,0.395,0.395,0.492,0,0,-1.8,1.3
ENSMUSG00000075113,OLFR1209,olfactory receptor 1209,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.373,10,-0.1,0.0585,-0.1,0.395,-0.395,0.492,0,0,-1.6,1.3
ENSMUSG00000093866,OLFR802,olfactory receptor 802,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.78,10,0,0,-0.1,0.395,-0.395,0.492,0,0,-1.8,0.9
ENSMUSG00000061387,OLFR1490,olfactory receptor 1490,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,1.1,3.5,10,-0.1,0.134,1,0.394,0.394,0.492,0,0,-0.4,2
ENSMUSG00000073897,OLFR17,olfactory receptor 17,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|axon guidance|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.874,10,0,0,0.1,0.393,0.393,0.493,0,0,-0.8,1.9
ENSMUSG00000053166,CDH22,cadherin 22,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|calcium-dependent cell-cell adhesion|,calcium ion binding|metal ion binding|,10,0,0,10,0.2,0.91,0.2,0.392,0.392,0.493,0,0,-1.1,1.7
ENSMUSG00000021961,4930578I06RIK,RIKEN cDNA 4930578I06 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.128,10,0.8,0.536,-0.1,0.39,-0.39,0.494,0,0,-0.6,2
ENSMUSG00000020434,4921536K21RIK,RIKEN cDNA 4921536K21 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.555,10,0,0,0.1,0.39,0.39,0.494,0,0,-1.9,0.8
ENSMUSG00000059493,NHS,Nance-Horan syndrome (human),None,lens development in camera-type eye|cell differentiation|,None,10,-0.2,0.238,10,-0.2,0.189,-0.2,0.39,-0.39,0.494,0,0,-1.5,1.4
ENSMUSG00000047117,ANKDD1B,ankyrin repeat and death domain containing 1B,cellular_component|,signal transduction|biological_process|,molecular_function|,9,-0.1,0.2,9,-0.2,0.257,-0.1,0.39,-0.39,0.494,0,0,-1.6,1.3
ENSMUSG00000092060,BEND4,BEN domain containing 4,cellular_component|,biological_process|,molecular_function|,10,0.2,0.846,10,0,0,0.1,0.389,0.389,0.495,0,0,-0.6,2
ENSMUSG00000041361,MYZAP,myocardial zonula adherens protein,cytoplasm|cytoskeleton|plasma membrane|membrane|cell junction|cortical actin cytoskeleton|extrinsic component of cytoplasmic side of plasma membrane|I band|,intracellular signal transduction|,protein binding|,2,-0.2,0.13,3,0.3,0.538,-0.2,0.387,-0.387,0.496,0,0,-1.7,1.9
ENSMUSG00000073375,LRRC30,leucine rich repeat containing 30,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.119,10,-0.5,0.638,-0.1,0.384,-0.384,0.497,0,0,-1.9,0.7
ENSMUSG00000004814,CCL24,chemokine (C-C motif) ligand 24,extracellular region|extracellular space|,positive regulation of endothelial cell proliferation|chemotaxis|inflammatory response|immune response|cytoskeleton organization|regulation of cell shape|positive regulation of cell migration|positive regulation of actin filament polymerization|positive regulation of Rac GTPase activity|positive regulation of angiogenesis|eosinophil chemotaxis|positive regulation of inflammatory response|positive regulation of eosinophil migration|,cytokine activity|chemokine activity|,10,-0.1,0.355,10,-0.1,0.0642,-0.1,0.384,-0.384,0.497,0,0,-1.9,1
ENSMUSG00000001420,TMEM79,transmembrane protein 79,cell|cytoplasm|lysosome|lysosomal membrane|Golgi apparatus|membrane|integral component of membrane|trans-Golgi network membrane|,epithelial cell maturation|hair follicle morphogenesis|cuticle development|regulated secretory pathway|positive regulation of epidermis development|establishment of skin barrier|cornification|,molecular_function|,10,-0.1,0.254,10,-0.1,0.166,-0.1,0.384,-0.384,0.497,0,0,-1.7,1.1
ENSMUSG00000078259,GM11554,predicted gene 11554,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.2,0.408,10,-0.1,0.0562,-0.1,0.379,-0.379,0.499,0,0,-1.7,1
ENSMUSG00000027908,TCHHL1,trichohyalin-like 1,cellular_component|,biological_process|,molecular_function|calcium ion binding|,10,-0.3,1.77,10,0.8,0.961,-0.2,0.376,-0.376,0.5,0,0,-0.9,2
ENSMUSG00000029530,CCR9,chemokine (C-C motif) receptor 9,plasma membrane|membrane|integral component of membrane|,chemotaxis|immune response|signal transduction|G-protein coupled receptor signaling pathway|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|,10,-0.1,0.372,10,0.1,0.0809,-0.1,0.376,-0.376,0.5,0,0,-1.7,1.1
ENSMUSG00000062563,CYS1,cystin 1,cytoplasm|cytoskeleton|plasma membrane|cilium|axoneme|axoneme|membrane|ciliary basal body|cell projection|membrane raft|extracellular vesicular exosome|,kidney development|inner ear development|,molecular_function|,10,1.1,3.12,10,0.1,0.143,1.1,0.376,0.376,0.5,0,0,-0.6,2
ENSMUSG00000094200,OLFR237-PS1,"olfactory receptor 237, pseudogene 1",None,None,None,10,0,0,10,0.3,1.38,0.1,0.375,0.375,0.501,0,0,-1,1.7
ENSMUSG00000055546,TIMD4,T cell immunoglobulin and mucin domain containing 4,membrane|integral component of membrane|,None,None,10,-0.1,0.281,10,-0.1,0.127,-0.1,0.373,-0.373,0.502,0,0,-1.8,1
ENSMUSG00000002020,LTBP2,latent transforming growth factor beta binding protein 2,extracellular region|extracellular space|extracellular matrix|extracellular vesicular exosome|,biological_process|,calcium ion binding|heparin binding|growth factor binding|,7,0.1,0.0201,7,-0.7,0.816,-0.5,0.373,-0.373,0.502,0,0,-2,0.9
ENSMUSG00000090122,KCNE1L,"potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene",voltage-gated potassium channel complex|membrane|integral component of membrane|,ion transport|regulation of heart contraction|cardiac muscle contraction|regulation of membrane repolarization|regulation of ventricular cardiac muscle cell membrane repolarization|regulation of atrial cardiac muscle cell membrane repolarization|potassium ion export|potassium ion transmembrane transport|ventricular cardiac muscle cell action potential|membrane repolarization during cardiac muscle cell action potential|atrial cardiac muscle cell action potential|regulation of heart rate by cardiac conduction|regulation of potassium ion transmembrane transport|negative regulation of potassium ion transmembrane transport|positive regulation of potassium ion transmembrane transport|regulation of cation channel activity|,voltage-gated potassium channel activity|potassium channel regulator activity|ion channel binding|voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization|,10,0.1,0.322,10,0.1,0.0811,0.1,0.368,0.368,0.504,0,0,-1.3,1.6
ENSMUSG00000079293,CLEC7A,"C-type lectin domain family 7, member a",plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,"response to yeast|detection of yeast|pattern recognition receptor signaling pathway|response to molecule of fungal origin|leukocyte activation involved in immune response|immune system process|cell surface pattern recognition receptor signaling pathway|phagocytosis, recognition|phagocytosis, recognition|phagocytosis, engulfment|inflammatory response|cell recognition|single organismal cell-cell adhesion|positive regulation of tumor necrosis factor production|innate immune response|positive regulation of phagocytosis|cellular response to molecule of fungal origin|",opsonin binding|(1->3)-beta-D-glucan binding|(1->3)-beta-D-glucan receptor activity|protein binding|signaling pattern recognition receptor activity|carbohydrate binding|polysaccharide binding|metal ion binding|,10,-0.2,0.885,10,0,0,-0.1,0.368,-0.368,0.504,0,0,-1.5,1.3
ENSMUSG00000006411,PVRL4,poliovirus receptor-related 4,plasma membrane|adherens junction|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,cell adhesion|single organismal cell-cell adhesion|,molecular_function|,10,-0.4,0.51,10,0.3,0.0683,-0.1,0.367,-0.367,0.505,0,0,-1.2,1.7
ENSMUSG00000061923,ODF1,outer dense fiber of sperm tails 1,outer dense fiber|nucleus|,multicellular organismal development|spermatogenesis|cell differentiation|,protein domain specific binding|,10,0,0,10,0.4,2.18,0.2,0.366,0.366,0.505,0,0,-0.6,1.9
ENSMUSG00000073774,KNCN,kinocilin,cytoplasm|microtubule cytoskeleton|membrane|integral component of membrane|apical plasma membrane|cuticular plate|ciliary basal body|neuronal cell body|apical part of cell|kinocilium|,biological_process|,molecular_function|,10,-0.1,0.0234,10,1.2,2.12,-0.1,0.366,-0.366,0.505,0,0,-1,2
ENSMUSG00000037254,ITIH2,"inter-alpha trypsin inhibitor, heavy chain 2",extracellular region|extracellular vesicular exosome|blood microparticle|,negative regulation of peptidase activity|hyaluronan metabolic process|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,-0.4,0.706,-0.1,0.364,-0.364,0.506,0,0,-1.6,1.3
ENSMUSG00000056270,PRR9,proline rich 9,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.517,10,1,1.02,-0.2,0.361,-0.361,0.508,0,0,-0.7,2
ENSMUSG00000031932,GPR83,G protein-coupled receptor 83,plasma membrane|membrane|integral component of membrane|nonmotile primary cilium|,signal transduction|G-protein coupled receptor signaling pathway|response to glucocorticoid|,signal transducer activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|,10,-0.1,0.12,10,-0.1,0.274,-0.1,0.36,-0.36,0.508,0,0,-1.7,1.1
ENSMUSG00000058153,SEZ6L,seizure related 6 homolog like,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|neuronal cell body|,adult locomotory behavior|cerebellar Purkinje cell layer development|synapse maturation|regulation of protein kinase C signaling|,molecular_function|,10,0,0,10,-0.1,0.492,-0.1,0.36,-0.36,0.508,0,0,-1.7,1.1
ENSMUSG00000040987,MILL2,MHC I like leukocyte 2,anchored component of external side of plasma membrane|,immune response-activating cell surface receptor signaling pathway|response to oxidative stress|response to heat|response to retinoic acid|gamma-delta T cell activation|negative regulation of defense response to virus by host|,protein binding|natural killer cell lectin-like receptor binding|,10,-0.4,1.7,10,0,0,-0.2,0.36,-0.36,0.508,0,0,-1.3,1.7
ENSMUSG00000035131,BRINP3,bone morphogenetic protein/retinoic acid inducible neural specific 3,extracellular region|mitochondrion|endoplasmic reticulum|dendrite|neuronal cell body|,cell cycle|cell cycle arrest|positive regulation of neuron differentiation|negative regulation of cell cycle|negative regulation of mitotic cell cycle|cellular response to retinoic acid|,molecular_function|,10,-0.3,0.268,10,-0.1,0.141,-0.1,0.36,-0.36,0.508,0,0,-1.7,1
ENSMUSG00000049028,OLFR873,olfactory receptor 873,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.3,0.875,-0.2,0.36,-0.36,0.508,0,0,-1.7,1
ENSMUSG00000049648,OLFR273,olfactory receptor 273,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,1.13,10,0,0,0.1,0.357,0.357,0.509,0,0,-1.1,1.8
ENSMUSG00000004360,9330159F19RIK,RIKEN cDNA 9330159F19 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.911,10,0,0,-0.1,0.356,-0.356,0.51,0,0,-1.8,1.1
ENSMUSG00000070906,IFNA11,interferon alpha 11,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,10,0.6,0.655,10,-0.1,0.0371,-0.1,0.355,-0.355,0.51,0,0,-1.1,1.8
ENSMUSG00000038421,FCRLA,Fc receptor-like A,extracellular region|cytoplasm|,cell differentiation|,protein binding|,10,0.2,0.605,10,0,0,0.1,0.355,0.355,0.51,0,0,-1.6,1.3
ENSMUSG00000078234,KLHDC7A,kelch domain containing 7A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,0.638,10,0.1,0.359,-0.1,0.351,-0.351,0.512,0,0,-1.7,1
ENSMUSG00000033361,PRRG3,proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane),cellular_component|extracellular region|membrane|integral component of membrane|,biological_process|,molecular_function|calcium ion binding|,10,0.3,0.873,10,-0.2,0.00816,0.3,0.351,0.351,0.512,0,0,-1.4,1.3
ENSMUSG00000047678,GPR82,G protein-coupled receptor 82,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,-0.4,1.65,-0.1,0.351,-0.351,0.512,0,0,-1.7,1.2
ENSMUSG00000037953,A4GNT,"alpha-1,4-N-acetylglucosaminyltransferase",cellular_component|,protein O-linked glycosylation|glycoprotein biosynthetic process|negative regulation of epithelial cell proliferation|,"acetylglucosaminyltransferase activity|acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.699,10,0,0,0.1,0.35,0.35,0.512,0,0,-1.3,1.5
ENSMUSG00000079355,ACKR4,atypical chemokine receptor 4,endosome|plasma membrane|membrane|integral component of membrane|,chemotaxis|signal transduction|G-protein coupled receptor signaling pathway|chemokine-mediated signaling pathway|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|scavenger receptor activity|chemokine binding|,10,0.1,0.309,10,-0.3,0.0746,0.1,0.349,0.349,0.513,0,0,-1.7,1.1
ENSMUSG00000044362,CCDC89,coiled-coil domain containing 89,intracellular|nucleus|cytoplasm|,biological_process|,protein binding|,10,0,0,10,-0.3,1.05,-0.1,0.346,-0.346,0.514,0,0,-1.7,1.1
ENSMUSG00000039084,CHAD,chondroadherin,extracellular region|proteinaceous extracellular matrix|,bone development|negative regulation of bone trabecula formation|,None,10,0,0,10,0.4,1.4,0.1,0.346,0.346,0.514,0,0,-0.8,1.9
ENSMUSG00000046975,OLFR1020,olfactory receptor 1020,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,-0.2,0.569,9,0,0,-0.1,0.346,-0.346,0.514,0,0,-1.7,1.2
ENSMUSG00000033032,AFAP1L1,actin filament associated protein 1-like 1,nucleus|cytoplasm|plasma membrane|cell junction|cell projection|,biological_process|,protein binding|,10,-0.2,0.284,10,-0.1,0.133,-0.2,0.345,-0.345,0.515,0,0,-2,0.7
ENSMUSG00000028544,SLC5A9,"solute carrier family 5 (sodium/glucose cotransporter), member 9",membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|transmembrane transport|,transporter activity|,10,0.4,0.473,10,0.1,0.0994,0.2,0.345,0.345,0.515,0,0,-1,1.8
ENSMUSG00000070369,ITGAD,"integrin, alpha D",integrin complex|membrane|integral component of membrane|,cell adhesion|integrin-mediated signaling pathway|activated T cell proliferation|,metal ion binding|protein heterodimerization activity|,10,-0.2,0.836,10,0,0,-0.1,0.345,-0.345,0.515,0,0,-1.8,1
ENSMUSG00000020545,LRRC72,leucine rich repeat containing 72,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.894,0.1,0.345,0.345,0.515,0,0,-1.5,1.4
ENSMUSG00000048186,BEND7,BEN domain containing 7,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.974,-0.1,0.344,-0.344,0.515,0,0,-1.8,1
ENSMUSG00000005540,FCER2A,"Fc receptor, IgE, low affinity II, alpha polypeptide",plasma membrane|external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,positive regulation of humoral immune response mediated by circulating immunoglobulin|positive regulation of nitric-oxide synthase activity|positive regulation of killing of cells of other organism|positive regulation of nitric-oxide synthase biosynthetic process|,IgE binding|carbohydrate binding|metal ion binding|,10,-0.1,0.000839,10,-0.1,0.374,-0.1,0.343,-0.343,0.516,0,0,-1.5,1.5
ENSMUSG00000074491,CLEC4G,"C-type lectin domain family 4, member g",plasma membrane|,negative regulation of T cell mediated immunity|negative regulation of T cell mediated immunity|negative regulation of T cell proliferation|negative regulation of T cell proliferation|,polysaccharide binding|,10,0,0,10,0.5,1.25,0.1,0.341,0.341,0.517,0,0,-0.9,1.8
ENSMUSG00000067212,H2-T23,"histocompatibility 2, T region locus 23",cell surface|membrane|integral component of membrane|MHC class I protein complex|extracellular vesicular exosome|,"positive regulation of T cell mediated cytotoxicity|immune system process|antigen processing and presentation of peptide antigen via MHC class I|antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent|immune response|antigen processing and presentation|inner ear development|",MHC class I protein binding|peptide antigen binding|,10,0.1,0.524,10,0,0,0.1,0.339,0.339,0.518,0,0,-1.4,1.5
ENSMUSG00000026147,COL9A1,"collagen, type IX, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|collagen type IX trimer|,tissue homeostasis|growth plate cartilage development|growth plate cartilage development|cartilage development|,metal ion binding|,9,-0.1,0.318,9,-0.1,0.0511,-0.1,0.337,-0.337,0.519,0,0,-1.9,1
ENSMUSG00000030930,CHST15,carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15,Golgi apparatus|membrane|integral component of membrane|,hexose biosynthetic process|,sulfotransferase activity|transferase activity|3'-phosphoadenosine 5'-phosphosulfate binding|N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity|,10,-0.1,0.406,10,0.1,0.0191,-0.1,0.337,-0.337,0.519,0,0,-1.5,1.4
ENSMUSG00000037736,LIMCH1,LIM and calponin homology domains 1,cellular_component|,biological_process|actomyosin structure organization|,molecular_function|actin binding|zinc ion binding|metal ion binding|,10,-0.2,1.42,10,0,0,-0.1,0.333,-0.333,0.521,0,0,-1.5,1.3
ENSMUSG00000045761,FAM179A,"family with sequence similarity 179, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.527,0.1,0.332,0.332,0.521,0,0,-1.4,1.5
ENSMUSG00000025870,ARL10,ADP-ribosylation factor-like 10,cellular_component|intracellular|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0.3,0.742,10,-1,2.09,0.2,0.33,0.33,0.522,0,0,-2,1.2
ENSMUSG00000023140,REG2,regenerating islet-derived 2,extracellular region|,suckling behavior|myelination|,carbohydrate binding|,10,-0.5,1.46,10,0.1,0.000621,0.2,0.326,0.326,0.524,0,0,-1.8,1
ENSMUSG00000049741,RXFP4,relaxin family peptide receptor 4,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,molecular_function|signal transducer activity|G-protein coupled receptor activity|angiotensin type II receptor activity|,10,0,0,10,0.2,1.09,0.1,0.323,0.323,0.526,0,0,-1.5,1.3
ENSMUSG00000047686,ZCCHC5,"zinc finger, CCHC domain containing 5",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0.1,0.249,10,-0.2,0.468,-0.2,0.322,-0.322,0.526,0,0,-1.5,1.2
ENSMUSG00000071398,2410004P03RIK,RIKEN cDNA 2410004P03 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.181,10,-0.1,0.172,-0.1,0.322,-0.322,0.526,0,0,-1.8,1.1
ENSMUSG00000021806,NID2,nidogen 2,extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|basement membrane|cell surface|extracellular matrix|extracellular vesicular exosome|,cell adhesion|cell-matrix adhesion|cell-matrix adhesion|,calcium ion binding|protein binding|,10,-0.1,0.787,10,0,0,-0.1,0.319,-0.319,0.528,0,0,-1.4,1.7
ENSMUSG00000039167,ELTD1,"EGF, latrophilin seven transmembrane domain containing 1",plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|calcium ion binding|protein dimerization activity|,10,0.1,0.395,10,0,0,0.1,0.319,0.319,0.528,0,0,-1.2,1.6
ENSMUSG00000026115,VWA3B,von Willebrand factor A domain containing 3B,cellular_component|,biological_process|,molecular_function|,10,0.1,0.304,10,-0.2,0.195,0.1,0.319,0.319,0.528,0,0,-1.6,1.2
ENSMUSG00000050234,GJA4,"gap junction protein, alpha 4",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,blood vessel development|calcium ion transport|cell communication|cell-cell signaling|,None,10,-0.1,0.392,10,0,0,-0.1,0.319,-0.319,0.528,0,0,-1.6,1.3
ENSMUSG00000034677,GPR142,G protein-coupled receptor 142,cytoplasm|plasma membrane|membrane|integral component of membrane|cell junction|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,-0.3,0.421,10,0.1,0.22,0.1,0.318,0.318,0.528,0,0,-1.3,1.5
ENSMUSG00000073923,OLFR657,olfactory receptor 657,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.209,10,0.1,0.138,0.1,0.317,0.317,0.529,0,0,-1.1,1.7
ENSMUSG00000073973,OLFR552,olfactory receptor 552,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.777,10,0.2,0.505,0.1,0.316,0.316,0.529,0,0,-1.6,1.3
ENSMUSG00000028441,1110017D15RIK,RIKEN cDNA 1110017D15 gene,manchette|nucleus|cytoplasm|cytoskeleton|perinuclear region of cytoplasm|perinuclear region of cytoplasm|,spermatogenesis|cell differentiation|cellular protein complex assembly|,alpha-tubulin binding|,10,-0.3,2.16,10,0,0,-0.2,0.315,-0.315,0.529,0,0,-1.5,1.3
ENSMUSG00000073965,OLFR568,olfactory receptor 568,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,1.56,10,-0.3,0.182,0.1,0.315,0.315,0.529,0,0,-1.6,1.2
ENSMUSG00000050425,MRGPRB2,"MAS-related GPR, member B2",cellular_component|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.2,0.249,10,-0.1,0.1,-0.1,0.314,-0.314,0.53,0,0,-1.8,1
ENSMUSG00000067522,OLFR76,olfactory receptor 76,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|olfactory receptor activity|,10,-0.3,1.38,10,0.1,0.226,-0.1,0.313,-0.313,0.53,0,0,-1.5,1.2
ENSMUSG00000045259,KLHDC9,kelch domain containing 9,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.487,10,0.2,0.0434,-0.1,0.311,-0.311,0.531,0,0,-1.4,1.5
ENSMUSG00000089717,OLFR275,olfactory receptor 275,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.735,10,0.1,0.0591,-0.1,0.31,-0.31,0.532,0,0,-1.6,1.2
ENSMUSG00000086596,SUSD5,sushi domain containing 5,cellular_component|,biological_process|,molecular_function|,10,0.8,1.43,10,0.1,0.317,0.1,0.306,0.306,0.534,0,0,-0.7,2
ENSMUSG00000066682,PILRB2,paired immunoglobin-like type 2 receptor beta 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0166,10,-0.8,1.62,0.1,0.305,0.305,0.534,0,0,-1.7,1.6
ENSMUSG00000021950,ANXA8,annexin A8,cytosol|plasma membrane|late endosome membrane|,blood coagulation|hemostasis|,"calcium ion binding|calcium-dependent phospholipid binding|phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-3,4-bisphosphate binding|metal ion binding|actin filament binding|",10,0.1,0.354,10,-0.2,0.708,-0.2,0.3,-0.3,0.537,0,0,-1.5,1.2
ENSMUSG00000009378,SLC16A12,"solute carrier family 16 (monocarboxylic acid transporters), member 12",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,-0.1,0.601,10,0,0,-0.1,0.3,-0.3,0.537,0,0,-1.8,1.1
ENSMUSG00000037016,FREM2,Fras1 related extracellular matrix protein 2,basement membrane|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,morphogenesis of an epithelium|cell communication|cell adhesion|homophilic cell adhesion|multicellular organismal development|inner ear development|,calcium ion binding|protein binding|metal ion binding|,10,0,0,10,-0.4,2.06,-0.2,0.298,-0.298,0.538,0,0,-1.8,0.9
ENSMUSG00000031022,BC051019,cDNA sequence BC051019,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.374,-0.1,0.297,-0.297,0.538,0,0,-1.7,1.2
ENSMUSG00000036185,SAPCD1,suppressor APC domain containing 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.127,10,-0.1,0.198,-0.1,0.296,-0.296,0.539,0,0,-1.3,1.7
ENSMUSG00000041468,GPR12,G-protein coupled receptor 12,plasma membrane|membrane|integral component of membrane|,cellular calcium ion homeostasis|signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|phosphatidylcholine binding|,10,-0.2,0.485,10,0,0,-0.1,0.296,-0.296,0.539,0,0,-1.7,1.1
ENSMUSG00000056492,GPR116,G protein-coupled receptor 116,plasma membrane|cell surface|membrane|integral component of membrane|cytoplasmic vesicle|,energy reserve metabolic process|regulation of lipid metabolic process|glucose homeostasis|surfactant homeostasis|fat cell differentiation|,molecular_function|,10,-0.2,0.18,10,-0.2,0.144,-0.2,0.295,-0.295,0.539,0,0,-1.7,1
ENSMUSG00000031394,OPN1MW,"opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)",photoreceptor outer segment|photoreceptor outer segment|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|visual perception|phototransduction|protein-chromophore linkage|positive regulation of cytokinesis|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|protein binding|photoreceptor activity|,10,-0.1,0.493,9,0,0,-0.1,0.293,-0.293,0.54,0,0,-1.7,1.2
ENSMUSG00000056822,OLFR166,olfactory receptor 166,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,8,0,0,8,0.4,1.01,0.2,0.293,0.293,0.54,0,0,-1.1,1.9
ENSMUSG00000044716,DOK7,docking protein 7,plasma membrane|membrane|cell junction|neuromuscular junction|synapse|,positive regulation of protein phosphorylation|neuromuscular junction development|neuromuscular junction development|receptor clustering|receptor clustering|positive regulation of protein tyrosine kinase activity|positive regulation of protein tyrosine kinase activity|,insulin receptor binding|protein binding|lipid binding|protein kinase binding|protein kinase binding|phosphatidylinositol binding|,10,-0.1,0.332,10,0,0,-0.1,0.293,-0.293,0.54,0,0,-1.7,1.2
ENSMUSG00000050505,PCDH20,protocadherin 20,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|biological_process|,calcium ion binding|poly(A) RNA binding|,10,-0.2,0.789,10,0,0,-0.1,0.292,-0.292,0.541,0,0,-1.7,1.1
ENSMUSG00000021750,FAM107A,"family with sequence similarity 107, member A",nucleus|neuron projection|neuron projection|,regulation of cell growth|,molecular_function|,10,0.1,0.182,10,0.1,0.136,0.1,0.29,0.29,0.542,0,0,-1.2,1.7
ENSMUSG00000038300,PTH2,parathyroid hormone 2,extracellular region|,cAMP biosynthetic process|neuropeptide signaling pathway|,receptor binding|,10,-0.1,0.46,10,0.2,1.27,0.1,0.288,0.288,0.543,0,0,-1.4,1.5
ENSMUSG00000036617,ETL4,enhancer trap locus 4,cytoplasm|,multicellular organismal development|embryonic skeletal system development|,None,10,0,0,10,-0.4,1.76,-0.2,0.287,-0.287,0.543,0,0,-1.9,0.8
ENSMUSG00000059900,TMEM40,transmembrane protein 40,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.487,10,0.3,1.55,0.2,0.286,0.286,0.544,0,0,-1.5,1.5
ENSMUSG00000027827,KCNAB1,"potassium voltage-gated channel, shaker-related subfamily, beta member 1",cytoplasm|voltage-gated potassium channel complex|integral component of membrane|,transport|ion transport|potassium ion transport|learning or memory|regulation of ion transmembrane transport|transmembrane transport|regulation of potassium ion transmembrane transporter activity|,voltage-gated ion channel activity|voltage-gated potassium channel activity|protein binding|,10,-0.2,0.593,10,0,0,-0.1,0.285,-0.285,0.544,0,0,-1.3,1.5
ENSMUSG00000019936,EPYC,epiphycan,extracellular region|proteinaceous extracellular matrix|,None,None,10,0,0,10,-0.1,0.4,-0.1,0.284,-0.284,0.545,0,0,-1.6,1.3
ENSMUSG00000030017,REG3G,regenerating islet-derived 3 gamma,extracellular region|cytoplasm|,MyD88-dependent toll-like receptor signaling pathway|acute-phase response|inflammatory response|positive regulation of keratinocyte proliferation|negative regulation of keratinocyte differentiation|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|positive regulation of wound healing|,carbohydrate binding|,10,-0.9,1.33,10,0,0,-0.1,0.284,-0.284,0.545,0,0,-2,0.7
ENSMUSG00000024440,PCDH12,protocadherin 12,plasma membrane|integral component of plasma membrane|cell-cell junction|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,glycogen metabolic process|cell adhesion|homophilic cell adhesion|calcium-dependent cell-cell adhesion|labyrinthine layer development|,calcium ion binding|,10,-0.3,1.07,10,0,0,-0.1,0.283,-0.283,0.545,0,0,-1.7,1.1
ENSMUSG00000033053,1700028P14RIK,RIKEN cDNA 1700028P14 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.4,1.55,10,0,0,-0.1,0.282,-0.282,0.546,0,0,-1.7,1.1
ENSMUSG00000079625,TM4SF19,transmembrane 4 L six family member 19,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0992,10,0.3,0.675,-0.1,0.282,-0.282,0.546,0,0,-1.5,1.3
ENSMUSG00000028264,SPACA1,sperm acrosome associated 1,acrosomal membrane|membrane|integral component of membrane|,acrosome assembly|spermatogenesis|,molecular_function|,10,0.1,0.0461,10,0.1,0.261,0.1,0.281,0.281,0.546,0,0,-1.1,1.7
ENSMUSG00000045246,KCNG4,"potassium voltage-gated channel, subfamily G, member 4",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.1,0.122,10,-0.1,0.184,-0.1,0.279,-0.279,0.547,0,0,-1.7,1.2
ENSMUSG00000049506,SPPL2C,signal peptide peptidase 2C,endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|integral component of cytoplasmic side of endoplasmic reticulum membrane|integral component of lumenal side of endoplasmic reticulum membrane|,proteolysis|biological_process|,"aspartic-type endopeptidase activity|peptidase activity|hydrolase activity|aspartic endopeptidase activity, intramembrane cleaving|protein homodimerization activity|",10,-0.1,0.0483,10,0.2,0.314,0.1,0.278,0.278,0.548,0,0,-1.6,1.3
ENSMUSG00000032473,CLDN18,claudin 18,plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,None,structural molecule activity|,10,0.1,0.174,10,0.1,0.129,0.1,0.276,0.276,0.549,0,0,-1.7,1.2
ENSMUSG00000074419,GM15448,predicted gene 15448,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0406,10,-0.1,0.261,-0.1,0.275,-0.275,0.55,0,0,-1.7,1.2
ENSMUSG00000052537,OLFR198,olfactory receptor 198,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.798,10,0,0,-0.1,0.275,-0.275,0.55,0,0,-1.6,1.3
ENSMUSG00000034275,IGSF9B,"immunoglobulin superfamily, member 9B",dendrite|neuronal cell body|inhibitory synapse|,homophilic cell adhesion|positive regulation of inhibitory postsynaptic membrane potential|,kinase binding|,10,-0.4,0.821,10,0,0,-0.1,0.274,-0.274,0.55,0,0,-1.6,1.3
ENSMUSG00000033007,ASIC4,acid-sensing (proton-gated) ion channel family member 4,membrane|integral component of membrane|,transport|ion transport|sodium ion transport|,sodium channel activity|,10,0,0,10,0.2,0.806,0.1,0.274,0.274,0.55,0,0,-1.2,1.7
ENSMUSG00000039795,ZFAND1,"zinc finger, AN1-type domain 1",cellular_component|,biological_process|,molecular_function|zinc ion binding|metal ion binding|,10,-0.5,1.37,10,0,0,-0.1,0.273,-0.273,0.551,0,0,-2,0.8
ENSMUSG00000032179,BMP5,bone morphogenetic protein 5,extracellular region|extracellular space|membrane-bounded vesicle|,skeletal system development|ossification|type B pancreatic cell development|multicellular organismal development|pattern specification process|negative regulation of cell proliferation|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of steroid biosynthetic process|cell differentiation|male genitalia development|negative regulation of aldosterone biosynthetic process|growth|negative regulation of insulin-like growth factor receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|positive regulation of epithelial cell proliferation|cartilage development|positive regulation of dendrite development|negative regulation of cortisol biosynthetic process|positive regulation of DNA-dependent DNA replication|,cytokine activity|protein binding|growth factor activity|BMP receptor binding|,10,0,0,10,0.3,1.4,0.1,0.273,0.273,0.551,0,0,-1.2,1.6
ENSMUSG00000060240,CEND1,cell cycle exit and neuronal differentiation 1,membrane|integral component of membrane|,adult walking behavior|cerebellar granular layer maturation|cerebellar Purkinje cell differentiation|radial glia guided migration of cerebellar granule cell|negative regulation of cerebellar granule cell precursor proliferation|,molecular_function|,10,-0.1,0.495,10,0,0,-0.1,0.273,-0.273,0.551,0,0,-1.9,0.9
ENSMUSG00000057207,OLFR1028,olfactory receptor 1028,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|,9,0.2,0.596,9,0,0,0.1,0.272,0.272,0.551,0,0,-1.5,1.4
ENSMUSG00000040600,EPS8L3,EPS8-like 3,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0,0,9,-0.2,0.609,-0.1,0.272,-0.272,0.551,0,0,-1.7,1.2
ENSMUSG00000030046,BMP10,bone morphogenetic protein 10,extracellular region|extracellular space|cytoplasm|cell surface|Z disc|,"cell adhesion|multicellular organismal development|heart development|adult heart development|negative regulation of endothelial cell migration|positive regulation of cardiac muscle hypertrophy|negative regulation of cardiac muscle hypertrophy|positive regulation of gene expression|positive regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of pathway-restricted SMAD protein phosphorylation|negative regulation of cell growth|negative regulation of cell migration|BMP signaling pathway|activin receptor signaling pathway|growth|sarcomere organization|positive regulation of transcription, DNA-templated|ventricular cardiac muscle tissue morphogenesis|ventricular cardiac muscle cell development|regulation of cardiac muscle contraction|cardiac muscle cell proliferation|positive regulation of cardiac muscle cell proliferation|positive regulation of sarcomere organization|heart trabecula formation|pathway-restricted SMAD protein phosphorylation|pathway-restricted SMAD protein phosphorylation|positive regulation of cell proliferation involved in heart morphogenesis|",cytokine activity|hormone activity|growth factor activity|receptor serine/threonine kinase binding|,10,-0.1,0.0379,10,-0.2,0.267,-0.1,0.271,-0.271,0.552,0,0,-1.8,1
ENSMUSG00000074738,B930041F14RIK,RIKEN cDNA B930041F14 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0288,10,-0.3,0.612,-0.1,0.27,-0.27,0.552,0,0,-1.4,1.5
ENSMUSG00000046408,1700067K01RIK,RIKEN cDNA 1700067K01 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.308,10,0,0,0.1,0.269,0.269,0.553,0,0,-1.3,1.6
ENSMUSG00000028989,ANGPTL7,angiopoietin-like 7,cellular_component|extracellular region|,None,None,10,-0.1,0.529,10,0,0,-0.1,0.268,-0.268,0.553,0,0,-1.6,1.3
ENSMUSG00000033434,GTPBP6,GTP binding protein 6 (putative),cellular_component|,biological_process|,nucleotide binding|molecular_function|GTP binding|metal ion binding|,10,0,0,10,-0.1,0.406,-0.1,0.268,-0.268,0.553,0,0,-1.7,1.2
ENSMUSG00000027858,TSPAN2,tetraspanin 2,plasma membrane|membrane|integral component of membrane|myelin sheath|myelin sheath|,inflammatory response|astrocyte development|astrocyte development|microglia development|microglia development|myelination|oligodendrocyte differentiation|axon development|,molecular_function|,10,-0.2,0.0321,10,0.4,1.11,-0.2,0.268,-0.268,0.553,0,0,-1.4,1.5
ENSMUSG00000075068,OLFR140,olfactory receptor 140,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.239,10,0.1,0.311,-0.1,0.268,-0.268,0.553,0,0,-1.6,1.2
ENSMUSG00000044772,SNTN,"sentan, cilia apical structure protein",cellular_component|cilium|cell projection|,biological_process|,molecular_function|calcium ion binding|,10,0.1,0.0913,10,0.1,0.2,0.1,0.266,0.266,0.554,0,0,-1.4,1.5
ENSMUSG00000073906,OLFR692,olfactory receptor 692,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.1,0.446,0.1,0.265,0.265,0.555,0,0,-1.1,1.8
ENSMUSG00000023935,SPATS1,"spermatogenesis associated, serine-rich 1",cellular_component|,biological_process|,molecular_function|,10,0.1,0.117,10,0.3,0.44,0.2,0.264,0.264,0.555,0,0,-1.4,1.7
ENSMUSG00000078487,ANKRD65,ankyrin repeat domain 65,cellular_component|,biological_process|,molecular_function|,9,-0.5,1.04,9,0.1,0.0668,-0.1,0.264,-0.264,0.555,0,0,-1.8,1
ENSMUSG00000028037,IFI44,interferon-induced protein 44,cytoplasm|,biological_process|,molecular_function|,10,-0.3,1.02,10,0,0,-0.1,0.262,-0.262,0.556,0,0,-1.7,1.1
ENSMUSG00000044296,ZFP879,zinc finger protein 879,intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|",nucleic acid binding|DNA binding|sequence-specific DNA binding transcription factor activity|metal ion binding|,10,0.1,0.61,10,-0.1,0.415,0.1,0.26,0.26,0.557,0,0,-1.8,1.1
ENSMUSG00000015484,FAM163A,"family with sequence similarity 163, member A",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.2,0.571,0.1,0.26,0.26,0.557,0,0,-1.5,1.3
ENSMUSG00000075478,SLITRK1,"SLIT and NTRK-like family, member 1",membrane|integral component of membrane|,nervous system development|axonogenesis|adult behavior|multicellular organism growth|homeostatic process|,molecular_function|,10,0.3,0.744,10,-0.1,0.24,0.2,0.256,0.256,0.559,0,0,-1.1,1.7
ENSMUSG00000024334,H2-OA,"histocompatibility 2, O region alpha locus",membrane|integral component of membrane|MHC class II protein complex|,immune system process|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of antigen processing and presentation of peptide antigen via MHC class II|antigen processing and presentation|antigen processing and presentation of exogenous peptide antigen via MHC class II|regulation of T cell differentiation|,MHC class II protein complex binding|,10,0.3,0.699,10,-0.1,0.354,0.2,0.255,0.255,0.56,0,0,-0.8,1.9
ENSMUSG00000075073,OLFR1256,olfactory receptor 1256,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.332,10,0.3,2.1,0.2,0.254,0.254,0.56,0,0,-1.2,1.6
ENSMUSG00000038591,COLEC10,collectin sub-family member 10,extracellular region|collagen trimer|nucleus|cytoplasm|cytosol|,defense response|heterophilic cell-cell adhesion|embryo development|,mannose binding|carbohydrate binding|,10,-0.2,0.885,10,0,0,-0.1,0.252,-0.252,0.561,0,0,-1.5,1.5
ENSMUSG00000069971,4933402J07RIK,RIKEN cDNA 4933402J07 gene,nucleus|,biological_process|,molecular_function|,10,-0.1,0.314,10,0,0,-0.1,0.252,-0.252,0.561,0,0,-1.6,1.3
ENSMUSG00000047293,GPR15,G protein-coupled receptor 15,cytoplasm|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|T cell migration|,signal transducer activity|G-protein coupled receptor activity|,10,0.3,0.506,10,0,0,0.2,0.251,0.251,0.562,0,0,-1,1.8
ENSMUSG00000007034,SLC44A4,"solute carrier family 44, member 4",cell|membrane|integral component of membrane|extracellular vesicular exosome|,acetylcholine biosynthetic process|positive regulation of cell growth|acetylcholine secretion|,molecular_function|,10,0.2,0.583,10,0,0,0.1,0.251,0.251,0.562,0,0,-0.8,1.9
ENSMUSG00000094012,GM10024,predicted gene 10024,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.969,-0.1,0.25,-0.25,0.562,0,0,-1.7,1.1
ENSMUSG00000075087,OLFR1240,olfactory receptor 1240,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.315,10,0,0,0.1,0.25,0.25,0.562,0,0,-1.5,1.4
ENSMUSG00000020234,4930404N11RIK,RIKEN cDNA 4930404N11 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.517,10,0,0,-0.1,0.245,-0.245,0.565,0,0,-1.8,1.1
ENSMUSG00000034990,OTOA,otoancorin,extracellular region|proteinaceous extracellular matrix|plasma membrane|membrane|apical plasma membrane|anchored component of membrane|,cell-matrix adhesion|sensory perception of sound|transmission of nerve impulse|,molecular_function|,10,-0.3,0.859,10,0,0,-0.1,0.244,-0.244,0.565,0,0,-1.7,1.1
ENSMUSG00000058740,KCNT1,"potassium channel, subfamily T, member 1",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated potassium channel activity|potassium channel activity|calcium-activated potassium channel activity|,10,0,0,10,-0.1,0.431,-0.1,0.244,-0.244,0.565,0,0,-1.5,1.4
ENSMUSG00000068407,RNASE12,"ribonuclease, RNase A family, 12 (non-active)",cellular_component|extracellular region|,biological_process|,molecular_function|nucleic acid binding|,10,0,0,10,-0.2,0.636,-0.1,0.243,-0.243,0.566,0,0,-1.8,1
ENSMUSG00000018919,TM4SF5,transmembrane 4 superfamily member 5,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,0.433,10,0,0,-0.1,0.242,-0.242,0.567,0,0,-1.8,0.9
ENSMUSG00000057240,MS4A13,"membrane-spanning 4-domains, subfamily A, member 13",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.333,10,-0.1,0.212,-0.1,0.242,-0.242,0.567,0,0,-1.6,1.4
ENSMUSG00000078668,GM11595,predicted gene 11595,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.9,0.726,10,-0.3,0.722,-0.4,0.241,-0.241,0.567,0,0,-2,0.3
ENSMUSG00000030911,ZP2,zona pellucida glycoprotein 2,extracellular region|proteinaceous extracellular matrix|multivesicular body|endoplasmic reticulum|Golgi apparatus|plasma membrane|membrane|integral component of membrane|secretory granule|extracellular matrix|,intracellular protein transport|single fertilization|binding of sperm to zona pellucida|prevention of polyspermy|,protein binding|acrosin binding|,10,0.1,0.323,10,0,0,0.1,0.241,0.241,0.567,0,0,-1.3,1.6
ENSMUSG00000041688,AMOT,angiomotin,stress fiber|ruffle|cytoplasm|actin filament|tight junction|tight junction|COP9 signalosome|external side of plasma membrane|cell surface|integral component of membrane|lamellipodium|lamellipodium|cell junction|endocytic vesicle|cytoplasmic vesicle|,vasculogenesis|in utero embryonic development|gastrulation with mouth forming second|establishment of cell polarity involved in ameboidal cell migration|chemotaxis|negative regulation of angiogenesis|actin cytoskeleton organization|regulation of cell migration|negative regulation of GTPase activity|cellular protein localization|cellular protein localization|hippo signaling|positive regulation of embryonic development|cell migration involved in gastrulation|negative regulation of vascular permeability|blood vessel endothelial cell migration|positive regulation of blood vessel endothelial cell migration|blood vessel morphogenesis|regulation of small GTPase mediated signal transduction|,receptor activity|protein binding|angiostatin binding|,10,-0.3,0.934,10,0,0,-0.1,0.24,-0.24,0.568,0,0,-1.4,1.5
ENSMUSG00000054000,TUSC1,tumor suppressor candidate 1,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.558,10,0,0,-0.1,0.239,-0.239,0.568,0,0,-1.7,1.2
ENSMUSG00000055978,FUT2,fucosyltransferase 2,Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,carbohydrate metabolic process|protein glycosylation|fucosylation|,"galactoside 2-alpha-L-fucosyltransferase activity|galactoside 2-alpha-L-fucosyltransferase activity|fucosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,0.2,0.505,10,0,0,0.1,0.238,0.238,0.569,0,0,-0.7,2
ENSMUSG00000055421,PCDH9,protocadherin 9,integral component of plasma membrane|membrane|integral component of membrane|growth cone|cell-cell contact zone|,cell adhesion|biological_process|,protein binding|,10,0.2,0.368,10,0,0,0.2,0.237,0.237,0.569,0,0,-1.6,1.4
ENSMUSG00000010841,1700006E09RIK,RIKEN cDNA 1700006E09 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.118,10,0.1,0.137,0.1,0.233,0.233,0.571,0,0,-1.2,1.7
ENSMUSG00000062278,GM11562,predicted gene 11562,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0.1,0.373,10,0,0,0.1,0.233,0.233,0.571,0,0,-1.4,1.6
ENSMUSG00000047014,CATSPERB,catsper channel auxiliary subunit beta,cilium|membrane|integral component of membrane|ion channel complex|CatSper complex|,multicellular organismal development|spermatogenesis|cell differentiation|sperm capacitation|,protein binding|,10,-0.1,0.496,10,0,0,-0.1,0.233,-0.233,0.571,0,0,-1.4,1.6
ENSMUSG00000026149,TM4SF20,transmembrane 4 L six family member 20,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.946,-0.1,0.233,-0.233,0.571,0,0,-1.6,1.3
ENSMUSG00000022132,CLDN10,claudin 10,cytoplasm|endoplasmic reticulum|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,transport|ion transport|,structural molecule activity|,10,0,0,10,0.2,0.471,0.1,0.232,0.232,0.572,0,0,-1.2,1.6
ENSMUSG00000039676,CAPSL,calcyphosine-like,cellular_component|cytoplasm|,biological_process|,calcium ion binding|metal ion binding|,9,-0.3,0.66,10,0,0,0.2,0.231,0.231,0.573,0,0,-1.3,1.7
ENSMUSG00000067578,CBLN4,cerebellin 4 precursor protein,extracellular region|extracellular space|cell|cell junction|synapse|,protein secretion|,protein binding|,10,0,0,10,0.2,0.426,0.1,0.229,0.229,0.573,0,0,-0.9,1.9
ENSMUSG00000091648,C2CD4D,C2 calcium-dependent domain containing 4D,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.207,10,-0.2,0.147,-0.1,0.227,-0.227,0.575,0,0,-1.8,1
ENSMUSG00000032021,CRTAM,cytotoxic and regulatory T cell molecule,plasma membrane|plasma membrane|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,detection of tumor cell|detection of tumor cell|detection of tumor cell|immune system process|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|cell recognition|cell recognition|cell recognition|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytotoxicity|positive regulation of cytokine secretion|positive regulation of cytokine secretion|detection of stimulus|detection of stimulus|detection of stimulus|,receptor binding|receptor binding|receptor binding|protein binding|,10,-0.2,0.502,10,0,0,-0.1,0.226,-0.226,0.575,0,0,-1.6,1.2
ENSMUSG00000040328,OLFR56,olfactory receptor 56,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.2,0.838,-0.1,0.226,-0.226,0.575,0,0,-1.5,1.3
ENSMUSG00000045989,4930451I11RIK,RIKEN cDNA 4930451I11 gene,cellular_component|,biological_process|,molecular_function|,9,-0.3,1.01,9,0.1,0.158,-0.2,0.225,-0.225,0.576,0,0,-1.9,0.9
ENSMUSG00000028794,A3GALT2,"alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)",Golgi apparatus|membrane|integral component of membrane|vesicle|,carbohydrate metabolic process|glycosphingolipid biosynthetic process|glycosphingolipid biosynthetic process|lipid glycosylation|,"alpha-1,3-galactosyltransferase activity|alpha-1,3-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|metal ion binding|N-acetyllactosaminide 3-alpha-galactosyltransferase activity|",10,-0.4,1.14,10,0,0,-0.1,0.223,-0.223,0.577,0,0,-1.9,0.9
ENSMUSG00000073735,DEFB18,defensin beta 18,cellular_component|extracellular region|,defense response|biological_process|defense response to bacterium|,molecular_function|,8,-0.8,1.01,8,0.7,0.983,0.1,0.221,0.221,0.578,0,0,-1.5,1.8
ENSMUSG00000035085,1700020L24RIK,RIKEN cDNA 1700020L24 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.408,10,0,0,0.1,0.221,0.221,0.578,0,0,-1.3,1.6
ENSMUSG00000070417,OLFR2,olfactory receptor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.348,-0.1,0.22,-0.22,0.579,0,0,-1.7,1.2
ENSMUSG00000094539,OLFR191,olfactory receptor 191,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,0.815,10,0,0,-0.2,0.219,-0.219,0.579,0,0,-1.8,1
ENSMUSG00000045509,GPR150,G protein-coupled receptor 150,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.1,0.002,10,0.2,0.46,0.1,0.218,0.218,0.58,0,0,-1.3,1.6
ENSMUSG00000024749,TMC1,transmembrane channel-like gene family 1,external side of plasma membrane|membrane|integral component of membrane|stereocilium bundle tip|,transport|ion transport|sensory perception of sound|regulation of ion transmembrane transport|detection of mechanical stimulus involved in sensory perception of sound|detection of mechanical stimulus involved in sensory perception of sound|vestibular reflex|auditory receptor cell development|calcium ion transmembrane transport|calcium ion transmembrane transport|,voltage-gated calcium channel activity|voltage-gated calcium channel activity|,10,0.8,0.81,10,-0.1,0.333,-0.1,0.217,-0.217,0.58,0,0,-1,2
ENSMUSG00000022824,MUC13,"mucin 13, epithelial transmembrane",extracellular region|extracellular space|cytosol|plasma membrane|membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,maintenance of gastrointestinal epithelium|,protein homodimerization activity|,8,0.2,0.37,8,-0.2,0.637,-0.1,0.216,-0.216,0.581,0,0,-1.6,1.4
ENSMUSG00000009654,OIT3,oncoprotein induced transcript 3,nucleus|,urate homeostasis|,None,10,0.4,0.484,10,0.1,0.0291,0.1,0.216,0.216,0.581,0,0,-0.9,1.8
ENSMUSG00000070368,PROK1,prokineticin 1,extracellular region|,activation of MAPK activity|angiogenesis|circadian rhythm|positive regulation of cell proliferation|regulation of angiogenesis|positive regulation of cell division|,G-protein coupled receptor binding|growth factor activity|,10,0.9,0.765,10,0,0,-0.1,0.214,-0.214,0.582,0,0,-1.1,2
ENSMUSG00000036062,N28178,expressed sequence N28178,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.18,10,-0.1,0.0537,-0.1,0.213,-0.213,0.582,0,0,-0.9,2
ENSMUSG00000072663,SPEF2,sperm flagellar 2,manchette|cytoplasm|Golgi apparatus|sperm midpiece|,immune system development|spermatogenesis|fertilization|multicellular organismal aging|axoneme assembly|embryonic neurocranium morphogenesis|skeletal system morphogenesis|brain morphogenesis|cilium morphogenesis|respiratory system development|,protein binding|,10,-0.2,0.15,10,0.3,1.85,0.1,0.213,0.213,0.582,0,0,-1.4,1.4
ENSMUSG00000041673,LRRC18,leucine rich repeat containing 18,cellular_component|cytoplasm|,biological_process|,molecular_function|,9,0.1,0.191,9,0.8,0.971,0.1,0.211,0.211,0.584,0,0,-0.9,2
ENSMUSG00000046637,TTC34,tetratricopeptide repeat domain 34,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.245,0.1,0.211,0.211,0.584,0,0,-1,1.9
ENSMUSG00000071531,GPRIN2,G protein regulated inducer of neurite outgrowth 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.272,-0.1,0.209,-0.209,0.584,0,0,-1.7,1.1
ENSMUSG00000075383,OLFR351,olfactory receptor 351,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.355,10,0,0,-0.1,0.209,-0.209,0.584,0,0,-1.6,1.3
ENSMUSG00000073680,TMEM88B,transmembrane protein 88B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.748,0.1,0.208,0.208,0.585,0,0,-1.4,1.6
ENSMUSG00000031936,HEPHL1,hephaestin-like 1,cellular_component|membrane|integral component of membrane|,transport|ion transport|copper ion transport|oxidation-reduction process|,ferroxidase activity|copper ion binding|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|metal ion binding|epoxyqueuosine reductase activity|,10,0,0,10,-0.2,0.639,-0.1,0.207,-0.207,0.585,0,0,-1.6,1.3
ENSMUSG00000032714,SYDE1,"synapse defective 1, Rho GTPase, homolog 1 (C. elegans)",intracellular|cytosol|cerebellar mossy fiber|synaptic membrane|,synaptonemal complex assembly|signal transduction|synaptic vesicle docking involved in exocytosis|positive regulation of GTPase activity|positive regulation of synaptic transmission|,GTPase activator activity|protein binding|protein complex binding|,10,-0.4,0.838,10,0,0,-0.1,0.205,-0.205,0.586,0,0,-2,0.8
ENSMUSG00000047518,SLFNL1,schlafen like 1,cellular_component|,biological_process|,nucleotide binding|molecular_function|ATP binding|,9,0.2,0.422,10,0,0,0.1,0.203,0.203,0.588,0,0,-1.2,1.7
ENSMUSG00000028778,HCRTR1,hypocretin (orexin) receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|feeding behavior|,signal transducer activity|G-protein coupled receptor activity|orexin receptor activity|peptide hormone binding|,9,0,0,9,-0.7,0.874,-0.1,0.203,-0.203,0.588,0,0,-2,0.8
ENSMUSG00000039899,FGL2,fibrinogen-like protein 2,extracellular region|extracellular vesicular exosome|,cytolysis|,None,10,-0.2,0.718,10,0.2,0.289,-0.1,0.202,-0.202,0.588,0,0,-1.5,1.4
ENSMUSG00000038259,GDF5,growth differentiation factor 5,extracellular region|extracellular space|plasma membrane|membrane|,chondrocyte differentiation|transmembrane receptor protein serine/threonine kinase signaling pathway|embryonic limb morphogenesis|positive regulation of chondrocyte differentiation|forelimb morphogenesis|hindlimb morphogenesis|growth|regulation of multicellular organism growth|negative regulation of neuron apoptotic process|positive regulation of neuron differentiation|negative regulation of epithelial cell proliferation|cartilage development|negative regulation of mesenchymal cell apoptotic process|,receptor binding|cytokine activity|protein binding|growth factor activity|,10,0.2,0.816,10,-0.4,1.2,-0.1,0.201,-0.201,0.589,0,0,-1.2,2
ENSMUSG00000079510,MDGA2,MAM domain containing glycosylphosphatidylinositol anchor 2,plasma membrane|membrane|anchored component of membrane|,pattern specification process|,molecular_function|,10,0.1,0.0243,10,0.1,0.195,0.1,0.2,0.2,0.589,0,0,-1.4,1.4
ENSMUSG00000038987,1700019L03RIK,RIKEN cDNA 1700019L03 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.1,10,-0.1,0.118,-0.1,0.199,-0.199,0.59,0,0,-0.9,2
ENSMUSG00000053977,CD8A,"CD8 antigen, alpha chain",external side of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,immune system process|T cell mediated immunity|cell surface receptor signaling pathway|T cell activation|cytotoxic T cell differentiation|positive regulation of calcium-mediated signaling|defense response to virus|,protein binding|protein kinase binding|protein homodimerization activity|,10,-0.1,0.213,10,0.1,0.181,-0.1,0.196,-0.196,0.592,0,0,-1.6,1.3
ENSMUSG00000018479,1700125H20RIK,RIKEN cDNA 1700125H20 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.582,10,0,0,-0.1,0.194,-0.194,0.593,0,0,-1.7,1.2
ENSMUSG00000073931,OLFR646,olfactory receptor 646,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0139,10,-0.5,1.42,-0.1,0.194,-0.194,0.593,0,0,-1.9,1
ENSMUSG00000039462,COL10A1,"collagen, type X, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|cell cortex|,None,None,10,0.3,0.704,10,0,0,-0.1,0.194,-0.194,0.593,0,0,-1.4,1.4
ENSMUSG00000066964,TMEM211,transmembrane protein 211,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.826,-0.1,0.193,-0.193,0.593,0,0,-1.7,1.1
ENSMUSG00000019146,CACNG2,"calcium channel, voltage-dependent, gamma subunit 2",voltage-gated calcium channel complex|membrane|integral component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,transport|ion transport|calcium ion transport|neuromuscular junction development|transmission of nerve impulse|regulation of ion transmembrane transport|regulation of membrane potential|neurological system process|membrane depolarization|membrane hyperpolarization|calcium ion transmembrane transport|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|ionotropic glutamate receptor binding|,10,-0.1,0.0962,10,-0.2,0.166,-0.1,0.192,-0.192,0.594,0,0,-1.7,1.2
ENSMUSG00000072511,HHLA1,HERV-H LTR-associating 1,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.2,0.795,10,0,0,0.1,0.191,0.191,0.595,0,0,-1,1.8
ENSMUSG00000043110,LRRN4,leucine rich repeat neuronal 4,integral component of plasma membrane|membrane|integral component of membrane|,long-term memory|visual learning|,molecular_function|,10,-0.1,0.27,10,0.2,0.0113,-0.1,0.191,-0.191,0.595,0,0,-1.5,1.4
ENSMUSG00000049015,OLFR1467,olfactory receptor 1467,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.135,10,0.1,0.0731,0.1,0.19,0.19,0.595,0,0,-1.5,1.5
ENSMUSG00000067528,OLFR1424,olfactory receptor 1424,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.6,10,0,0,-0.3,0.19,-0.19,0.595,0,0,-2,0.6
ENSMUSG00000033595,LGI3,"leucine-rich repeat LGI family, member 3",extracellular region|synaptic vesicle|cell junction|cytoplasmic vesicle|neuron projection|synapse|,exocytosis|regulation of exocytosis|,catalytic activity|protein binding|,10,-0.1,0.321,10,0,0,-0.1,0.187,-0.187,0.597,0,0,-1.6,1.3
ENSMUSG00000046272,OLFR1444,olfactory receptor 1444,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.49,10,0.1,0.273,0.1,0.187,0.187,0.597,0,0,-1.1,1.7
ENSMUSG00000063297,LUZP2,leucine zipper protein 2,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0.7,2.58,0.1,0.186,0.186,0.597,0,0,-0.6,2
ENSMUSG00000030159,CLEC1B,"C-type lectin domain family 1, member b",integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|platelet formation|,transmembrane signaling receptor activity|carbohydrate binding|,10,0.2,0.634,10,0,0,0.2,0.186,0.186,0.597,0,0,-1.4,1.5
ENSMUSG00000048612,MYOF,myoferlin,nucleus|plasma membrane|caveola|membrane|integral component of membrane|cytoplasmic vesicle|intracellular membrane-bounded organelle|extracellular vesicular exosome|,plasma membrane repair|regulation of vascular endothelial growth factor receptor signaling pathway|cellular response to heat|,phospholipid binding|phospholipid binding|,10,0.2,0.784,10,0,0,0.1,0.184,0.184,0.598,0,0,-0.9,1.9
ENSMUSG00000069911,FAM196B,"family with sequence similarity 196, member B",cellular_component|,biological_process|,molecular_function|,10,0.2,0.927,10,0,0,0.1,0.182,0.182,0.599,0,0,-1.2,1.7
ENSMUSG00000055409,NELL1,NEL-like 1,extracellular region|extracellular space|nucleus|nuclear envelope|cytoplasm|perinuclear region of cytoplasm|,regulation of gene expression|cell differentiation|positive regulation of bone mineralization|negative regulation of osteoblast proliferation|positive regulation of apoptotic process|regulation of osteoblast differentiation|positive regulation of osteoblast differentiation|positive regulation of ossification|protein homotrimerization|negative regulation of cyclin catabolic process|,protein kinase C binding|calcium ion binding|heparin binding|identical protein binding|,10,0.1,0.134,10,0.1,0.059,0.1,0.176,0.176,0.603,0,0,-1,1.8
ENSMUSG00000049149,OLFR1258,olfactory receptor 1258,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.218,10,-0.1,0.0349,0.1,0.176,0.176,0.603,0,0,-1.3,1.6
ENSMUSG00000020607,FAM84A,"family with sequence similarity 84, member A",cellular_component|,biological_process|,molecular_function|,10,0.4,1.37,10,0,0,0.2,0.174,0.174,0.604,0,0,-0.9,1.8
ENSMUSG00000042757,TMEM108,transmembrane protein 108,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.356,10,0,0,0.1,0.173,0.173,0.605,0,0,-1.4,1.5
ENSMUSG00000039601,RCAN2,regulator of calcineurin 2,intracellular|,response to stress|response to stress|response to oxidative stress|short-term memory|calcium-mediated signaling|locomotion involved in locomotory behavior|calcineurin-NFAT signaling cascade|calcineurin-NFAT signaling cascade|,nucleotide binding|,10,0.4,0.603,10,0,0,0.1,0.173,0.173,0.605,0,0,-1.8,1.2
ENSMUSG00000021414,FAM217A,"family with sequence similarity 217, member A",cellular_component|,biological_process|,molecular_function|,10,0.1,0.045,10,-0.2,0.234,-0.1,0.173,-0.173,0.605,0,0,-1.5,1.3
ENSMUSG00000092622,KHDC3,"KH domain containing 3, subcortical maternal complex member",cytoplasm|cell cortex|protein complex|apical cortex|,protein phosphorylation|cell cycle|mitotic spindle assembly checkpoint|multicellular organismal development|spindle assembly involved in mitosis|,RNA binding|protein binding|,10,-0.4,1.46,10,0.1,0.163,0.1,0.173,0.173,0.605,0,0,-1.7,1.1
ENSMUSG00000044819,OXGR1,oxoglutarate (alpha-ketoglutarate) receptor 1,plasma membrane|membrane|integral component of membrane|,adenosine receptor signaling pathway|signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|,G-protein coupled adenosine receptor activity|purine nucleoside binding|signal transducer activity|G-protein coupled receptor activity|AMP binding|,10,0.1,0.00938,10,0.1,0.181,0.1,0.173,0.173,0.605,0,0,-1.1,1.7
ENSMUSG00000095831,OLFR453,olfactory receptor 453,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.2,0.92,0.1,0.172,0.172,0.605,0,0,-1.3,1.6
ENSMUSG00000052417,OLFR720,olfactory receptor 720,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0125,10,-0.2,0.45,-0.1,0.172,-0.172,0.605,0,0,-1.3,1.6
ENSMUSG00000071847,APCDD1,adenomatosis polyposis coli down-regulated 1,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,hair follicle development|Wnt signaling pathway|negative regulation of Wnt signaling pathway|astrocyte cell migration|,Wnt-protein binding|,10,-0.1,0.181,10,0.1,0.309,-0.2,0.171,-0.171,0.606,0,0,-1.5,1.3
ENSMUSG00000017204,GSDMA,gasdermin A,cytoplasm|perinuclear region of cytoplasm|,apoptotic process|,molecular_function|,10,-0.2,0.575,10,0,0,-0.1,0.17,-0.17,0.607,0,0,-1.6,1.2
ENSMUSG00000028294,1700003M02RIK,RIKEN cDNA 1700003M02 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,1.14,10,-0.2,1.17,0.1,0.17,0.17,0.607,0,0,-1.3,1.5
ENSMUSG00000047330,KCNE4,"potassium voltage-gated channel, Isk-related subfamily, gene 4",voltage-gated potassium channel complex|membrane|integral component of membrane|apical plasma membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated potassium channel activity|potassium channel activity|,10,0.2,0.257,10,-0.1,0.0354,0.1,0.17,0.17,0.607,0,0,-1.4,1.5
ENSMUSG00000039683,SDK1,sidekick homolog 1 (chicken),membrane|integral component of membrane|extracellular vesicular exosome|,cell adhesion|,molecular_function|,10,-0.5,1.2,10,0.1,0.0514,0.1,0.17,0.17,0.607,0,0,-1.7,1.4
ENSMUSG00000078507,AADACL3,arylacetamide deacetylase-like 3,cellular_component|membrane|integral component of membrane|,biological_process|metabolic process|,"molecular_function|phospholipase activity|prenylcysteine methylesterase activity|lipase activity|hydrolase activity|1-oxa-2-oxocycloheptane lactonase activity|sulfolactone hydrolase activity|3,4-dihydrocoumarin hydrolase activity|butyrolactone hydrolase activity|endosulfan lactone lactonase activity|L-ascorbate 6-phosphate lactonase activity|Ser-tRNA(Thr) hydrolase activity|Ala-tRNA(Pro) hydrolase activity|Cys-tRNA(Pro) hydrolase activity|Ser(Gly)-tRNA(Ala) hydrolase activity|all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity|retinyl-palmitate esterase activity|carboxylic ester hydrolase activity|mannosyl-oligosaccharide 1,6-alpha-mannosidase activity|mannosyl-oligosaccharide 1,3-alpha-mannosidase activity|methyl indole-3-acetate esterase activity|methyl salicylate esterase activity|methyl jasmonate esterase activity|",10,0.1,0.174,10,0.1,0.0116,0.1,0.169,0.169,0.607,0,0,-1.3,1.6
ENSMUSG00000012705,RETN,resistin,extracellular region|extracellular space|extracellular space|nucleus|extracellular vesicular exosome|,positive regulation of collagen metabolic process|positive regulation of smooth muscle cell migration|response to insulin|fat cell differentiation|positive regulation of smooth muscle cell proliferation|positive regulation of synaptic transmission|negative regulation of feeding behavior|positive regulation of progesterone secretion|,hormone activity|,10,0,0,10,-0.2,0.528,-0.1,0.169,-0.169,0.607,0,0,-1.7,1.1
ENSMUSG00000032057,4833427G06RIK,RIKEN cDNA 4833427G06 gene,cellular_component|,biological_process|,molecular_function|,10,0.5,2.6,10,-0.3,0.541,0.3,0.169,0.169,0.607,0,0,-1,1.8
ENSMUSG00000040037,NEGR1,neuronal growth regulator 1,plasma membrane|membrane|dendrite|anchored component of membrane|neuronal cell body|extracellular vesicular exosome|,cell adhesion|locomotory behavior|feeding behavior|positive regulation of neuron projection development|single organismal cell-cell adhesion|,molecular_function|,10,-0.2,0.361,10,-0.1,0.0506,-0.1,0.169,-0.169,0.607,0,0,-1.9,1
ENSMUSG00000026830,ERMN,"ermin, ERM-like protein",cytoplasm|cytoskeleton|cell cortex|filopodium|internode region of axon|internode region of axon|paranode region of axon|paranode region of axon|neuronal cell body|myelin sheath|extracellular vesicular exosome|,morphogenesis of a branching structure|actin filament organization|actin filament organization|regulation of cell shape|regulation of cell shape|regulation of cell projection organization|regulation of cell projection organization|,actin binding|actin filament binding|,10,-0.4,0.65,10,0,0,-0.1,0.169,-0.169,0.607,0,0,-1.8,1
ENSMUSG00000054588,GBP10,guanylate-binding protein 10,cytoplasmic vesicle|extracellular vesicular exosome|,defense response to protozoan|defense response to Gram-positive bacterium|defense response to Gram-positive bacterium|cellular response to lipopolysaccharide|cellular response to interferon-gamma|,molecular_function|,10,-0.2,0.581,10,0.1,0.218,-0.1,0.167,-0.167,0.608,0,0,-1.6,1.3
ENSMUSG00000042671,RGS8,regulator of G-protein signaling 8,cytoplasm|plasma membrane|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|GTPase activator activity|,10,-0.1,0.0997,10,-0.2,0.211,-0.1,0.166,-0.166,0.609,0,0,-1.7,1.1
ENSMUSG00000044313,MAB21L3,mab-21-like 3 (C. elegans),cellular_component|,biological_process|,molecular_function|,10,-0.1,0.165,10,0.6,1.7,0.4,0.166,0.166,0.609,0,0,-1,1.8
ENSMUSG00000022321,CDH10,cadherin 10,plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|,calcium ion binding|metal ion binding|,10,0.4,1.35,10,0,0,0.1,0.165,0.165,0.609,0,0,-0.7,2
ENSMUSG00000020658,EFR3B,EFR3 homolog B (S. cerevisiae),cellular_component|,biological_process|,molecular_function|,10,-0.2,0.312,10,0,0,-0.1,0.164,-0.164,0.61,0,0,-1.5,1.4
ENSMUSG00000020140,LGR5,leucine rich repeat containing G protein coupled receptor 5,Golgi apparatus|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|trans-Golgi network membrane|,signal transduction|G-protein coupled receptor signaling pathway|inner ear development|positive regulation of canonical Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|protein-hormone receptor activity|,10,-0.2,0.818,10,0,0,-0.1,0.164,-0.164,0.61,0,0,-1.6,1.3
ENSMUSG00000029072,TAS1R3,"taste receptor, type 1, member 3",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of sweet taste|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|sensory perception of sweet taste|sensory perception of sweet taste|sensory perception of umami taste|,signal transducer activity|G-protein coupled receptor activity|protein binding|taste receptor activity|taste receptor activity|sweet taste receptor activity|,10,0.1,0.361,10,0,0,0.1,0.162,0.162,0.611,0,0,-1.3,1.6
ENSMUSG00000045326,FNDC7,fibronectin type III domain containing 7,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0.2,1.04,0.1,0.161,0.161,0.612,0,0,-1.2,1.6
ENSMUSG00000075324,FIGN,fidgetin,nucleus|cytoplasm|cytoskeleton|microtubule|nuclear matrix|,cell cycle|mitotic nuclear division|locomotory behavior|cell division|,nucleotide binding|ATP binding|protein C-terminus binding|,10,-0.1,0.0498,10,-0.3,0.3,-0.1,0.161,-0.161,0.612,0,0,-1.9,0.9
ENSMUSG00000079103,TGM7,transglutaminase 7,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,-0.1,0.0471,10,-0.1,0.129,-0.1,0.16,-0.16,0.612,0,0,-1.6,1.3
ENSMUSG00000038463,OLFML2B,olfactomedin-like 2B,extracellular region|extracellular matrix|,extracellular matrix organization|,protein homodimerization activity|extracellular matrix binding|,10,0.6,1.62,10,0,0,-0.1,0.158,-0.158,0.613,0,0,-0.9,1.9
ENSMUSG00000035349,MIA2,melanoma inhibitory activity 2,extracellular region|endoplasmic reticulum exit site|,cholesterol homeostasis|triglyceride homeostasis|,molecular_function|,10,-0.2,0.525,10,0.2,0.178,-0.1,0.156,-0.156,0.615,0,0,-1.3,1.6
ENSMUSG00000079246,SLC35F4,"solute carrier family 35, member F4",cellular_component|membrane|integral component of membrane|,transport|biological_process|,molecular_function|,10,-0.2,0.569,10,0,0,-0.1,0.156,-0.156,0.615,0,0,-1.9,1
ENSMUSG00000030897,CNGA4,cyclic nucleotide gated channel alpha 4,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|intracellular cyclic nucleotide activated cation channel complex|perikaryon|,"transport|ion transport|cation transport|phototransduction, visible light|sensory perception of smell|ion transmembrane transport|regulation of ion transmembrane transport|regulation of membrane potential|response to stimulus|protein heterotetramerization|transmembrane transport|potassium ion transmembrane transport|",nucleotide binding|ion channel activity|intracellular cyclic nucleotide activated cation channel activity|intracellular cAMP activated cation channel activity|intracellular cAMP activated cation channel activity|intracellular cGMP activated cation channel activity|intracellular cGMP activated cation channel activity|voltage-gated potassium channel activity|cAMP binding|cGMP binding|cGMP binding|,10,-0.2,0.521,10,0,0,-0.1,0.155,-0.155,0.615,0,0,-1.8,1.1
ENSMUSG00000023945,SLC5A7,"solute carrier family 5 (choline transporter), member 7",plasma membrane|plasma membrane|membrane|integral component of membrane|integral component of membrane|neuronal cell body|,"transport|ion transport|sodium ion transport|synaptic transmission, cholinergic|neuromuscular synaptic transmission|acetylcholine biosynthetic process|acetylcholine biosynthetic process|choline transport|choline transport|choline transport|ion transmembrane transport|sodium ion transmembrane transport|neurotransmitter biosynthetic process|transmembrane transport|",transporter activity|choline:sodium symporter activity|protein binding|choline transmembrane transporter activity|choline transmembrane transporter activity|choline transmembrane transporter activity|symporter activity|choline binding|,10,-0.2,1.22,10,0.1,0.413,-0.2,0.154,-0.154,0.616,0,0,-1.9,0.9
ENSMUSG00000042680,GAREM,"GRB2 associated, regulator of MAPK1",cellular_component|,epidermal growth factor receptor signaling pathway|positive regulation of cell proliferation|positive regulation of cell division|positive regulation of ERK1 and ERK2 cascade|cellular response to epidermal growth factor stimulus|,proline-rich region binding|,10,0,0,10,0.2,0.409,0.1,0.154,0.154,0.616,0,0,-1.3,1.6
ENSMUSG00000057699,TAS2R131,"taste receptor, type 2, member 131",membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|response to stimulus|sensory perception of taste|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0.5,1.35,0.4,0.153,0.153,0.616,0,0,-0.7,1.9
ENSMUSG00000040576,WBSCR28,Williams-Beuren syndrome chromosome region 28 (human),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0173,10,0.4,0.456,0.2,0.151,0.151,0.617,0,0,-1,1.8
ENSMUSG00000079539,OBP2B,odorant binding protein 2B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.6,0.954,0.1,0.15,0.15,0.618,0,0,-0.7,2
ENSMUSG00000028589,1700012P22RIK,RIKEN cDNA 1700012P22 gene,cellular_component|,biological_process|,molecular_function|,10,0.3,0.701,10,0,0,0.1,0.15,0.15,0.618,0,0,-1.1,1.7
ENSMUSG00000020701,TMEM132E,transmembrane protein 132E,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.2,0.472,0.1,0.149,0.149,0.618,0,0,-1,1.9
ENSMUSG00000050321,NETO1,neuropilin (NRP) and tolloid (TLL)-like 1,plasma membrane|postsynaptic density|membrane|integral component of membrane|cell junction|kainate selective glutamate receptor complex|synapse|postsynaptic membrane|excitatory synapse|,memory|visual learning|regulation of neuronal synaptic plasticity|regulation of long-term neuronal synaptic plasticity|receptor localization to synapse|positive regulation of excitatory postsynaptic membrane potential|,protein binding|ionotropic glutamate receptor binding|,10,-0.2,0.952,10,0,0,-0.1,0.148,-0.148,0.619,0,0,-1.9,0.9
ENSMUSG00000057135,SCIMP,SLP adaptor and CSK interacting membrane protein,immunological synapse|membrane|integral component of membrane|leading edge membrane|uropod membrane|tetraspanin-enriched microdomain|,positive regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 cascade|,protein binding|,10,0,0,10,-0.4,0.698,-0.2,0.147,-0.147,0.62,0,0,-1.8,1
ENSMUSG00000070867,TRABD2B,TraB domain containing 2B,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|integral component of organelle membrane|extracellular vesicular exosome|,proteolysis|metabolic process|Wnt signaling pathway|protein oxidation|negative regulation of Wnt signaling pathway|,metalloendopeptidase activity|peptidase activity|cysteine-type peptidase activity|metallopeptidase activity|hydrolase activity|Wnt-protein binding|metal ion binding|,10,-0.1,0.501,10,0.1,0.395,0.1,0.146,0.146,0.62,0,0,-1,1.8
ENSMUSG00000058743,KCNJ14,"potassium inwardly-rectifying channel, subfamily J, member 14",membrane|integral component of membrane|dendrite|neuronal cell body|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|,10,0,0,10,-0.1,0.402,-0.1,0.146,-0.146,0.62,0,0,-1.7,1.2
ENSMUSG00000039742,FAM71F1,"family with sequence similarity 71, member F1",cellular_component|,biological_process|,molecular_function|,10,-0.7,0.252,10,-0.1,0.2,-0.3,0.146,-0.146,0.62,0,0,-2,0.4
ENSMUSG00000032334,LOXL1,lysyl oxidase-like 1,acrosomal vesicle|extracellular region|proteinaceous extracellular matrix|basement membrane|cytoplasm|extracellular matrix|extracellular matrix|,oxidation-reduction process|,"copper ion binding|protein binding|aspartate oxidase activity|oxidoreductase activity|oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor|D-lysine oxidase activity|metal ion binding|",10,-0.2,0.523,10,0.1,0.33,-0.1,0.142,-0.142,0.623,0,0,-1.6,1.3
ENSMUSG00000070498,TMEM132B,transmembrane protein 132B,cellular_component|,biological_process|,molecular_function|,10,0.4,0.801,10,-0.1,0.272,-0.1,0.142,-0.142,0.623,0,0,-1.2,1.7
ENSMUSG00000034923,LY6G6F,"lymphocyte antigen 6 complex, locus G6F",cellular_component|,biological_process|,molecular_function|,10,0.1,0.0355,10,0.2,0.204,0.1,0.142,0.142,0.623,0,0,-1,1.8
ENSMUSG00000063919,SRRM4,serine/arginine repetitive matrix 4,nucleus|,"regulation of alternative mRNA splicing, via spliceosome|mRNA processing|nervous system development|sensory perception of sound|RNA splicing|cell differentiation|regulation of RNA splicing|",RNA binding|mRNA binding|,10,0.2,1.45,10,0,0,0.1,0.142,0.142,0.623,0,0,-1.7,1.2
ENSMUSG00000005983,1700037C18RIK,RIKEN cDNA 1700037C18 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.178,10,-0.3,0.0327,-0.1,0.141,-0.141,0.623,0,0,-1.8,1.1
ENSMUSG00000042256,PTCHD4,patched domain containing 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|hedgehog receptor activity|,10,0,0,10,-0.2,0.366,-0.1,0.141,-0.141,0.623,0,0,-1.6,1.3
ENSMUSG00000057751,MEGF6,multiple EGF-like-domains 6,cellular_component|extracellular region|,biological_process|,calcium ion binding|,10,0.3,0.793,10,-0.1,0.124,0.1,0.141,0.141,0.623,0,0,-1.3,1.6
ENSMUSG00000067642,GPR113,G protein-coupled receptor 113,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,-0.3,0.716,10,0,0,-0.3,0.136,-0.136,0.626,0,0,-2,0.7
ENSMUSG00000042708,SHCBP1L,Shc SH2-domain binding protein 1-like,cellular_component|,biological_process|,protein binding|,10,-0.1,0.679,10,0,0,-0.1,0.136,-0.136,0.626,0,0,-1.5,1.5
ENSMUSG00000064177,GHRL,ghrelin,extracellular region|extracellular region|extracellular space|cytoplasm|axon|,"activation of MAPK activity|gastric acid secretion|negative regulation of endothelial cell proliferation|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|actin polymerization or depolymerization|adult feeding behavior|visual learning|response to hormone|dendrite development|dendrite development|positive regulation of insulin secretion|regulation of response to food|positive regulation of response to food|positive regulation of appetite|positive regulation of appetite|positive regulation of appetite|negative regulation of interleukin-1 beta production|negative regulation of locomotion|regulation of cell proliferation|negative regulation of circadian sleep/wake cycle, REM sleep|negative regulation of tumor necrosis factor biosynthetic process|negative regulation of apoptotic process|response to estrogen|negative regulation of interleukin-6 biosynthetic process|positive regulation of circadian sleep/wake cycle, non-REM sleep|negative regulation of insulin secretion|negative regulation of insulin secretion|decidualization|negative regulation of inflammatory response|positive regulation of corticotropin secretion|positive regulation of cortisol secretion|positive regulation of synapse assembly|positive regulation of synapse assembly|regulation of excitatory postsynaptic membrane potential|positive regulation of growth hormone secretion|positive regulation of protein tyrosine kinase activity|",G-protein coupled receptor binding|hormone activity|hormone activity|growth hormone-releasing hormone activity|protein tyrosine kinase activator activity|ghrelin receptor binding|,10,-0.2,0.627,10,0.2,0.768,0.1,0.135,0.135,0.627,0,0,-1.9,1
ENSMUSG00000034139,SERPINI2,"serine (or cysteine) peptidase inhibitor, clade I, member 2",extracellular region|extracellular space|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|negative regulation of endopeptidase activity|regulation of cell adhesion|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.4,1.11,10,0,0,-0.2,0.133,-0.133,0.628,0,0,-1.9,0.8
ENSMUSG00000094734,OLFR799,olfactory receptor 799,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,1.17,10,-0.1,0.125,0.1,0.132,0.132,0.628,0,0,-1.1,1.8
ENSMUSG00000049804,ARMCX4,"armadillo repeat containing, X-linked 4",cellular_component|,biological_process|,molecular_function|,10,-0.8,3.11,10,0.6,0.925,-0.7,0.132,-0.132,0.628,0,0,-2,1.1
ENSMUSG00000060508,NLRP9B,"NLR family, pyrin domain containing 9B",cellular_component|cytoplasm|,biological_process|,nucleotide binding|molecular_function|ATP binding|,10,0,0,10,0.1,0.357,0.1,0.131,0.131,0.629,0,0,-1.4,1.6
ENSMUSG00000075427,OLFR288,olfactory receptor 288,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,0.721,10,-0.2,0.437,0.1,0.13,0.13,0.629,0,0,-1.1,1.7
ENSMUSG00000026156,B3GAT2,"beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)",cellular_component|Golgi apparatus|membrane|integral component of membrane|,carbohydrate biosynthetic process|,galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity|glucuronosyltransferase activity|transferase activity|metal ion binding|,10,-0.2,0.736,10,0.6,1,0.1,0.129,0.129,0.63,0,0,-1.6,1.5
ENSMUSG00000047102,TAS2R139,"taste receptor, type 2, member 139",membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|bitter taste receptor activity|,10,0,0,10,0.2,0.726,0.1,0.129,0.129,0.63,0,0,-1.5,1.4
ENSMUSG00000068615,GJD2,"gap junction protein, delta 2",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,action potential|cell communication|cell-cell signaling|synaptic transmission|visual perception|,protein binding|,10,0,0,10,0.7,1.42,0.1,0.128,0.128,0.631,0,0,-0.7,2
ENSMUSG00000030427,LILRA6,"leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.241,0.1,0.128,0.128,0.631,0,0,-1.2,1.7
ENSMUSG00000045111,TAAR6,trace amine-associated receptor 6,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,trace-amine receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|,10,0,0,10,-0.2,1.27,-0.1,0.128,-0.128,0.631,0,0,-1.3,1.6
ENSMUSG00000063430,WSCD2,WSC domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.628,10,0,0,-0.1,0.127,-0.127,0.631,0,0,-1.6,1.1
ENSMUSG00000024306,CCDC178,coiled coil domain containing 178,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.9,3.16,0.9,0.127,0.127,0.631,0,0,-0.5,2
ENSMUSG00000073945,OLFR618,olfactory receptor 618,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.3,0.244,10,0,0,0.3,0.127,0.127,0.631,0,0,-1,1.8
ENSMUSG00000042379,ESM1,endothelial cell-specific molecule 1,cellular_component|extracellular region|,angiogenesis|regulation of cell growth|sprouting angiogenesis|positive regulation of cell proliferation|positive regulation of hepatocyte growth factor receptor signaling pathway|,hepatocyte growth factor receptor binding|integrin binding|insulin-like growth factor binding|,10,0.2,0.558,10,0,0,0.1,0.126,0.126,0.632,0,0,-1.4,1.5
ENSMUSG00000034660,GALP,galanin-like peptide,cellular_component|extracellular region|,neuropeptide signaling pathway|regulation of appetite|behavioral response to starvation|,receptor binding|hormone activity|,10,-0.2,0.677,10,0.1,0.19,0.2,0.123,0.123,0.634,0,0,-1,1.8
ENSMUSG00000067613,5430421N21RIK,RIKEN cDNA 5430421N21 gene,extracellular space|intermediate filament|,aging|hair cycle|,molecular_function|,10,-0.2,0.862,10,0.1,0.158,-0.1,0.122,-0.122,0.634,0,0,-1.6,1.3
ENSMUSG00000029328,HNRNPDL,heterogeneous nuclear ribonucleoprotein D-like,nucleus|nucleus|cytoplasm|extracellular vesicular exosome|,"transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of gene expression|mRNA metabolic process|",nucleotide binding|nucleic acid binding|DNA binding|double-stranded DNA binding|single-stranded DNA binding|RNA binding|poly(A) binding|poly(G) binding|poly(A) RNA binding|,10,0.1,0.524,10,0,0,0.1,0.122,0.122,0.634,0,0,-1.3,1.6
ENSMUSG00000025557,SLC15A1,"solute carrier family 15 (oligopeptide transporter), member 1",membrane|integral component of membrane|,transport|oligopeptide transport|protein transport|peptide transport|oligopeptide transmembrane transport|negative regulation of amino acid transport|,transporter activity|proton-dependent oligopeptide secondary active transmembrane transporter activity|oligopeptide transporter activity|symporter activity|channel inhibitor activity|,10,0.1,0.416,10,0,0,0.1,0.12,0.12,0.636,0,0,-1.3,1.7
ENSMUSG00000047225,OLFR684,olfactory receptor 684,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,1.04,10,0,0,0.1,0.119,0.119,0.636,0,0,-1.8,1.1
ENSMUSG00000025172,ANKRD2,ankyrin repeat domain 2 (stretch responsive muscle),euchromatin|nucleus|nucleus|nucleus|cytoplasm|cytosol|cytosol|myofibril|sarcomere|I band|I band|intracellular membrane-bounded organelle|,skeletal muscle cell differentiation|negative regulation of myoblast differentiation|negative regulation of myoblast differentiation|,protein binding|titin binding|protein kinase B binding|protein kinase B binding|,10,0.1,0.34,10,0,0,0.1,0.117,0.117,0.637,0,0,-1.3,1.6
ENSMUSG00000063651,CNFN,cornifelin,cornified envelope|cytoplasm|extracellular vesicular exosome|,biological_process|keratinization|,molecular_function|,10,-0.2,0.801,10,0,0,-0.1,0.116,-0.116,0.638,0,0,-1.7,1.2
ENSMUSG00000046191,PCDHB20,protocadherin beta 20,plasma membrane|membrane|integral component of membrane|,cell adhesion|,molecular_function|,10,0.1,0.329,10,-1.5,1.94,0.1,0.114,0.114,0.639,0,0,-3,0.7
ENSMUSG00000055177,CSTL1,cystatin-like 1,cellular_component|,biological_process|negative regulation of peptidase activity|,molecular_function|cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0.2,0.576,10,0,0,0.1,0.114,0.114,0.639,0,0,-1.7,1.3
ENSMUSG00000025726,SLC28A1,"solute carrier family 28 (sodium-coupled nucleoside transporter), member 1",membrane|apical plasma membrane|,purine nucleobase transport|pyrimidine nucleobase transport|sodium ion transmembrane transport|pyrimidine-containing compound transmembrane transport|nucleoside transmembrane transport|,pyrimidine nucleobase transmembrane transporter activity|pyrimidine- and adenine-specific:sodium symporter activity|,10,0.2,0.593,10,0,0,0.1,0.113,0.113,0.639,0,0,-1.2,1.7
ENSMUSG00000035295,WDR38,WD repeat domain 38,cellular_component|,hematopoietic progenitor cell differentiation|,molecular_function|,10,-0.3,0.703,10,0.3,0.467,0.1,0.113,0.113,0.639,0,0,-1.2,1.6
ENSMUSG00000035626,OLFR1509,olfactory receptor 1509,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0332,10,0.1,0.0905,0.1,0.113,0.113,0.639,0,0,-1.6,1.3
ENSMUSG00000075211,OLFR1006,olfactory receptor 1006,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.3,1,0.2,0.113,0.113,0.639,0,0,-1.1,1.7
ENSMUSG00000027355,TMCO5,transmembrane and coiled-coil domains 5,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.166,0.1,0.112,0.112,0.64,0,0,-1.2,1.7
ENSMUSG00000042631,XKR7,X Kell blood group precursor related family member 7 homolog,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.412,10,-0.2,0.448,0.1,0.111,0.111,0.641,0,0,-1.5,1.4
ENSMUSG00000007480,MC5R,melanocortin 5 receptor,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cAMP biosynthetic process|,signal transducer activity|G-protein coupled receptor activity|melanocortin receptor activity|hormone binding|,10,-0.2,0.305,10,0.5,1.65,0.3,0.111,0.111,0.641,0,0,-1,1.7
ENSMUSG00000062961,CCDC177,coiled-coil domain containing 177,cellular_component|,biological_process|,molecular_function|,10,0.1,0.357,10,-0.1,0.23,0.1,0.11,0.11,0.641,0,0,-1.3,1.6
ENSMUSG00000024936,KCNK7,"potassium channel, subfamily K, member 7",integral component of plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|potassium channel activity|,10,0.1,0.0181,10,0.2,0.297,0.1,0.11,0.11,0.641,0,0,-1.2,1.7
ENSMUSG00000096035,GM1045,predicted gene 1045,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.405,10,0,0,-0.1,0.109,-0.109,0.642,0,0,-1.6,1.3
ENSMUSG00000042268,SLC26A9,"solute carrier family 26, member 9",cell surface|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|extracellular vesicular exosome|,anion transport|chloride transport|chloride transport|regulation of pH|sulfate transport|positive regulation of gene expression|bicarbonate transport|bicarbonate transport|ion transmembrane transport|transmembrane transport|chloride transmembrane transport|,chloride channel activity|secondary active sulfate transmembrane transporter activity|bicarbonate transmembrane transporter activity|sulfate transmembrane transporter activity|anion:anion antiporter activity|anion:anion antiporter activity|ATPase binding|,10,0,0,10,-0.9,3.24,-0.8,0.108,-0.108,0.642,0,0,-2,0.4
ENSMUSG00000079164,TLR5,toll-like receptor 5,membrane|integral component of membrane|,positive regulation of cytokine production|immune system process|MyD88-dependent toll-like receptor signaling pathway|inflammatory response|signal transduction|positive regulation of interleukin-8 production|positive regulation of toll-like receptor signaling pathway|toll-like receptor 5 signaling pathway|defense response to bacterium|innate immune response|positive regulation of nitric oxide biosynthetic process|regulation of cytokine secretion|,transmembrane signaling receptor activity|interleukin-1 receptor binding|protein binding|,10,0.2,0.531,10,0,0,0.1,0.106,0.106,0.644,0,0,-1.4,1.6
ENSMUSG00000096682,IFNA5,interferon alpha 5,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|type I interferon receptor binding|,10,0.1,0.259,10,-0.1,0.0354,0.1,0.105,0.105,0.644,0,0,-1.3,1.6
ENSMUSG00000032978,GUCA2B,guanylate cyclase activator 2b (retina),extracellular region|extracellular vesicular exosome|,cGMP biosynthetic process|excretion|body fluid secretion|regulation of cyclic nucleotide biosynthetic process|negative regulation of blood pressure|,guanylate cyclase activator activity|,10,0.1,0.183,10,0,0,0.1,0.105,0.105,0.644,0,0,-1.4,1.6
ENSMUSG00000035279,SSC5D,"scavenger receptor cysteine rich family, 5 domains",extracellular region|extracellular space|intracellular|cytoplasm|membrane|extracellular matrix|,immune system process|receptor-mediated endocytosis|defense response|multicellular organismal development|detection of bacterial lipoprotein|innate immune response|defense response to Gram-negative bacterium|defense response to Gram-positive bacterium|regulation of interleukin-8 secretion|negative regulation of interleukin-8 secretion|,fibronectin binding|scavenger receptor activity|protein binding|laminin binding|extracellular matrix binding|,10,0,0,10,-0.2,0.76,-0.1,0.104,-0.104,0.645,0,0,-1.7,1.1
ENSMUSG00000042433,E230019M04RIK,RIKEN cDNA E230019M04 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.471,-0.1,0.102,-0.102,0.646,0,0,-1.7,1.2
ENSMUSG00000070823,GM1043,predicted gene 1043,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.489,10,0,0,-0.1,0.1,-0.1,0.647,0,0,-1.8,1.1
ENSMUSG00000027886,1700013F07RIK,RIKEN cDNA 1700013F07 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.594,10,0,0,-0.1,0.1,-0.1,0.647,0,0,-1.6,1.3
ENSMUSG00000004031,BRINP2,bone morphogenic protein/retinoic acid inducible neural-specific 2,extracellular region|endoplasmic reticulum|dendrite|neuronal cell body|,cell cycle|cell cycle arrest|positive regulation of neuron differentiation|negative regulation of cell cycle|negative regulation of mitotic cell cycle|cellular response to retinoic acid|,molecular_function|,10,0,0,10,0.1,0.315,-0.1,0.0997,-0.0997,0.647,0,0,-1.4,1.5
ENSMUSG00000036560,LGI4,"leucine-rich repeat LGI family, member 4",extracellular region|extracellular space|,adult locomotory behavior|glial cell proliferation|Schwann cell development|glial cell development|myelination in peripheral nervous system|gliogenesis|gliogenesis|neuron maturation|myelination|myelination|,protein binding|,10,0,0,10,1.2,2.77,0.1,0.0979,0.0979,0.648,0,0,-0.6,2
ENSMUSG00000037922,BANK1,B cell scaffold protein with ankyrin repeats 1,cellular_component|,B cell activation|positive regulation of MAPK cascade|negative regulation of translational initiation|negative regulation of B cell activation|negative regulation of protein kinase B signaling|negative regulation of interleukin-6 secretion|,protein binding|,10,0.1,0.0563,10,-0.1,0.0531,-0.1,0.0969,-0.0969,0.648,0,0,-1.6,1.2
ENSMUSG00000018844,FNDC8,fibronectin type III domain containing 8,nucleus|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.161,-0.1,0.0959,-0.0959,0.649,0,0,-1.7,1.2
ENSMUSG00000059128,IFNL2,interferon lambda 2,cellular_component|extracellular region|extracellular space|,mucosal immune response|JAK-STAT cascade|positive regulation of immune response|defense response to virus|,molecular_function|cytokine activity|,10,-0.2,0.957,10,0,0,-0.1,0.0954,-0.0954,0.649,0,0,-1.6,1.3
ENSMUSG00000025482,ODF3,outer dense fiber of sperm tails 3,outer dense fiber|cytoplasm|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,molecular_function|,9,-0.3,0.535,9,0.5,0.715,-0.1,0.0953,-0.0953,0.649,0,0,-1.3,1.7
ENSMUSG00000061561,OLFR373,olfactory receptor 373,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,1.11,10,0,0,-0.1,0.09,-0.09,0.652,0,0,-1.7,1.2
ENSMUSG00000050685,CCDC54,coiled-coil domain containing 54,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.186,10,0.1,0.155,0.1,0.088,0.088,0.654,0,0,-1.3,1.6
ENSMUSG00000095373,OLFR705,olfactory receptor 705,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.88,10,0,0,-0.1,0.0871,-0.0871,0.654,0,0,-1.9,0.8
ENSMUSG00000069421,OLFR810,olfactory receptor 810,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.15,10,0.2,0.211,0.1,0.087,0.087,0.654,0,0,-1.1,1.7
ENSMUSG00000050891,TATDN1,TatD DNase domain containing 1,nucleus|intracellular organelle|,DNA catabolic process|nucleic acid phosphodiester bond hydrolysis|,"nuclease activity|deoxyribonuclease activity|hydrolase activity|endodeoxyribonuclease activity, producing 5'-phosphomonoesters|metal ion binding|",10,0.1,0.269,10,-0.1,0.17,-0.1,0.0866,-0.0866,0.654,0,0,-1.6,1.3
ENSMUSG00000028197,COL24A1,"collagen, type XXIV, alpha 1",cellular_component|extracellular region|proteinaceous extracellular matrix|collagen trimer|,hematopoietic progenitor cell differentiation|,molecular_function|extracellular matrix structural constituent|,10,-0.2,0.452,10,0.1,0.0982,-0.1,0.086,-0.086,0.655,0,0,-1.7,1.2
ENSMUSG00000041482,PIEZO2,piezo-type mechanosensitive ion channel component 2,plasma membrane|membrane|integral component of membrane|,transport|ion transport|cation transport|cation transport|ion transmembrane transport|regulation of membrane potential|,cation channel activity|mechanically-gated ion channel activity|,10,0,0,10,0.1,0.122,0.1,0.0851,0.0851,0.655,0,0,-1.3,1.6
ENSMUSG00000071506,TMEM139,transmembrane protein 139,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.717,10,0,0,0.1,0.0845,0.0845,0.656,0,0,-1.6,1.3
ENSMUSG00000020216,JSRP1,junctional sarcoplasmic reticulum protein 1,endoplasmic reticulum|membrane|sarcoplasmic reticulum|,skeletal muscle contraction|striated muscle contraction|regulation of ryanodine-sensitive calcium-release channel activity|protein localization to membrane|,protein binding|,10,-0.2,0.434,10,0,0,-0.1,0.0839,-0.0839,0.656,0,0,-1.6,1.3
ENSMUSG00000043948,OLFR691,olfactory receptor 691,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1.2,3.33,10,0,0,-1.2,0.0832,-0.0832,0.656,0,0,-2,1
ENSMUSG00000023995,TSPO2,translocator protein 2,endoplasmic reticulum|membrane|integral component of membrane|,transport|biological_process|,cholesterol binding|,10,-0.1,0.189,10,0,0,-0.1,0.0807,-0.0807,0.658,0,0,-1.6,1.2
ENSMUSG00000029126,NSG1,neuron specific gene family member 1,endosome|Golgi apparatus|membrane|integral component of membrane|lateral plasma membrane|postsynaptic membrane|,dopamine receptor signaling pathway|clathrin coat assembly|,clathrin light chain binding|,10,0.2,0.695,10,0,0,0.1,0.0789,0.0789,0.659,0,0,-1.8,1.1
ENSMUSG00000049353,RD3,retinal degeneration 3,None,visual perception|response to stimulus|retina development in camera-type eye|,None,10,0.2,0.631,10,0,0,0.1,0.0786,0.0786,0.659,0,0,-1.1,1.8
ENSMUSG00000034795,CCDC122,coiled-coil domain containing 122,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0397,10,-0.1,0.248,-0.1,0.0776,-0.0776,0.659,0,0,-1.7,1.2
ENSMUSG00000043122,A530016L24RIK,RIKEN cDNA A530016L24 gene,plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.147,-0.1,0.0752,-0.0752,0.661,0,0,-1.6,1.4
ENSMUSG00000049420,TMEM200A,transmembrane protein 200A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.011,10,-0.1,0.0708,-0.1,0.0744,-0.0744,0.661,0,0,-1.8,1.1
ENSMUSG00000053522,LGALS7,"lectin, galactose binding, soluble 7",extracellular region|nucleus|cytoplasm|extracellular vesicular exosome|,apoptotic process|biological_process|,molecular_function|carbohydrate binding|,10,0.2,0.959,10,-1.1,2.27,0.1,0.0733,0.0733,0.662,0,0,-2,0.8
ENSMUSG00000050232,CXCR3,chemokine (C-X-C motif) receptor 3,intracellular|plasma membrane|external side of plasma membrane|external side of plasma membrane|cell surface|membrane|integral component of membrane|,angiogenesis|negative regulation of endothelial cell proliferation|regulation of leukocyte migration|chemotaxis|inflammatory response|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|positive regulation of cell proliferation|T cell chemotaxis|negative regulation of angiogenesis|calcium-mediated signaling|positive regulation of cAMP metabolic process|positive regulation of cAMP-mediated signaling|positive regulation of angiogenesis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of chemotaxis|positive regulation of release of sequestered calcium ion into cytosol|chemokine-mediated signaling pathway|chemokine (C-C motif) ligand 11 production|negative regulation of execution phase of apoptosis|positive regulation of execution phase of apoptosis|,signal transducer activity|receptor activity|G-protein coupled receptor activity|chemokine receptor activity|C-X-C chemokine receptor activity|chemokine binding|C-X-C chemokine binding|,10,0.1,0.52,10,0,0,0.1,0.0695,0.0695,0.664,0,0,-1.3,1.7
ENSMUSG00000044359,P2RY4,"pyrimidinergic receptor P2Y, G-protein coupled, 4",plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|,signal transduction|G-protein coupled receptor signaling pathway|transepithelial chloride transport|,signal transducer activity|G-protein coupled receptor activity|ATP binding|pyrimidine nucleotide binding|G-protein coupled purinergic nucleotide receptor activity|UTP-activated nucleotide receptor activity|,10,-0.1,0.358,10,0.2,0.783,-0.1,0.0682,-0.0682,0.665,0,0,-1.6,1.4
ENSMUSG00000050788,OLFR419,olfactory receptor 419,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,1.17,10,0.1,0.0278,-0.1,0.0679,-0.0679,0.665,0,0,-1.8,1
ENSMUSG00000050158,OLFR165,olfactory receptor 165,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0585,10,-0.1,0.0141,-0.1,0.0661,-0.0661,0.666,0,0,-2,0.9
ENSMUSG00000022375,LRRC6,leucine rich repeat containing 6 (testis),cytoplasm|cytoplasm|cilium|cell projection|,cilium movement|sperm motility|outer dynein arm assembly|inner dynein arm assembly|motile cilium assembly|epithelial cilium movement involved in determination of left/right asymmetry|reproductive system development|,molecular_function|,10,0.3,0.802,10,-0.2,0.373,0.1,0.0651,0.0651,0.666,0,0,-1.2,1.7
ENSMUSG00000032530,LYZL4,lysozyme-like 4,extracellular region|nucleus|,biological_process|cell wall macromolecule catabolic process|,molecular_function|lysozyme activity|,10,-0.2,0.38,10,0,0,-0.1,0.0646,-0.0646,0.667,0,0,-1.7,1.2
ENSMUSG00000030769,SLC5A11,"solute carrier family 5 (sodium/glucose cotransporter), member 11",membrane|integral component of membrane|,transport|ion transport|sodium ion transport|apoptotic process|carbohydrate transport|transmembrane transport|,transporter activity|symporter activity|,10,-0.3,1.1,10,0,0,-0.1,0.0643,-0.0643,0.667,0,0,-1.6,1.3
ENSMUSG00000027955,FAM198B,"family with sequence similarity 198, member B",Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.632,10,-0.1,0.155,-0.1,0.0623,-0.0623,0.668,0,0,-1.3,1.6
ENSMUSG00000052675,ZFP112,zinc finger protein 112,cellular_component|intracellular|nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|biological_process|",molecular_function|nucleic acid binding|DNA binding|metal ion binding|,10,0,0,10,-0.1,0.462,-0.1,0.0621,-0.0621,0.668,0,0,-1.7,1.2
ENSMUSG00000070423,OLFR558,olfactory receptor 558,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.254,10,0,0,0.1,0.0597,0.0597,0.67,0,0,-1.2,1.7
ENSMUSG00000040570,RUNDC3B,RUN domain containing 3B,cellular_component|,biological_process|,molecular_function|,10,0.9,2.28,10,0,0,0.1,0.058,0.058,0.671,0,0,-0.5,2
ENSMUSG00000031424,KIR3DL1,"killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1",cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.3,0.865,0.1,0.0575,0.0575,0.671,0,0,-1.8,1.2
ENSMUSG00000004110,CACNA1E,"calcium channel, voltage-dependent, R type, alpha 1E subunit",plasma membrane|voltage-gated calcium channel complex|voltage-gated calcium channel complex|membrane|integral component of membrane|perikaryon|,behavioral fear response|regulation of heart rate|transport|ion transport|calcium ion transport|synaptic transmission|locomotory behavior|visual learning|transmission of nerve impulse|sensory perception of pain|sperm motility|regulation of ion transmembrane transport|glucose homeostasis|fear response|response to pain|behavioral response to pain|neurological system process|transmembrane transport|regulation of insulin secretion involved in cellular response to glucose stimulus|calcium ion import|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|regulation of somatostatin secretion|,ion channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|calcium ion binding|high voltage-gated calcium channel activity|metal ion binding|protein N-terminus binding|,10,0,0,10,-0.2,0.572,-0.1,0.0573,-0.0573,0.671,0,0,-1.5,1.4
ENSMUSG00000048721,FNDC9,fibronectin type III domain containing 9,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.0441,10,-0.1,0.0179,-0.1,0.0564,-0.0564,0.672,0,0,-1.6,1.4
ENSMUSG00000050921,P2RY10,"purinergic receptor P2Y, G-protein coupled 10",plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled purinergic nucleotide receptor activity|,10,0.1,0.198,10,0,0,0.1,0.0561,0.0561,0.672,0,0,-1.3,1.7
ENSMUSG00000045174,AMER3,APC membrane recruitment 3,cellular_component|plasma membrane|membrane|,biological_process|Wnt signaling pathway|,molecular_function|lipid binding|,10,0,0,10,0.1,0.428,0.1,0.055,0.055,0.673,0,0,-1.7,1.3
ENSMUSG00000015467,EGFL8,EGF-like domain 8,cellular_component|extracellular region|,biological_process|,calcium ion binding|,10,0.1,0.0652,10,0,0,0.1,0.0543,0.0543,0.673,0,0,-1.2,1.7
ENSMUSG00000027971,NDST4,N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4,Golgi apparatus|membrane|integral component of membrane|,metabolic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|catalytic activity|GPI-anchor transamidase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|[heparan sulfate]-glucosamine N-sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|hydrolase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|deacetylase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|coenzyme F390-A hydrolase activity|coenzyme F390-G hydrolase activity|hydroxyjasmonate sulfotransferase activity|",9,-0.8,1.68,10,-0.1,0.0125,-0.4,0.0535,-0.0535,0.673,0,0,-2,0.6
ENSMUSG00000036873,2410004B18RIK,RIKEN cDNA 2410004B18 gene,cellular_component|,biological_process|,poly(A) RNA binding|,10,0,0,10,-0.1,0.294,-0.1,0.0527,-0.0527,0.674,0,0,-1.7,1.3
ENSMUSG00000048304,SLITRK3,"SLIT and NTRK-like family, member 3",membrane|integral component of membrane|,axonogenesis|,molecular_function|,10,-0.1,0.282,10,0.3,0.463,-0.1,0.0521,-0.0521,0.674,0,0,-1.2,1.7
ENSMUSG00000038540,TMC3,transmembrane channel-like gene family 3,cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,-0.1,0.329,10,0,0,-0.1,0.052,-0.052,0.674,0,0,-1.8,1.1
ENSMUSG00000059648,RNASE11,"ribonuclease, RNase A family, 11 (non-active)",cellular_component|extracellular region|,biological_process|,molecular_function|nucleic acid binding|,10,0.2,0.237,10,-0.2,0.598,-0.1,0.0517,-0.0517,0.674,0,0,-1.2,1.8
ENSMUSG00000042216,SGSM1,small G protein signaling modulator 1,Golgi apparatus|,regulation of Rab GTPase activity|,Rab GTPase activator activity|,10,-0.1,0.406,10,0,0,-0.1,0.0517,-0.0517,0.674,0,0,-2,0.8
ENSMUSG00000060254,OLFR980,olfactory receptor 980,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.0992,-0.1,0.0515,-0.0515,0.674,0,0,-1.8,1.2
ENSMUSG00000038879,NIPAL2,NIPA-like domain containing 2,cellular_component|membrane|integral component of membrane|,biological_process|magnesium ion transport|,molecular_function|magnesium ion transmembrane transporter activity|,10,-0.1,0.469,10,0,0,0.1,0.051,0.051,0.675,0,0,-1.6,1.3
ENSMUSG00000035184,FAM124A,"family with sequence similarity 124, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.641,-0.1,0.0506,-0.0506,0.675,0,0,-1.7,1.2
ENSMUSG00000071113,MBOAT4,membrane bound O-acyltransferase domain containing 4,endoplasmic reticulum|membrane|integral component of membrane|integral component of endoplasmic reticulum membrane|,peptidyl-serine octanoylation|peptidyl-serine octanoylation|,"dihydrolipoamide branched chain acyltransferase activity|sterol O-acyltransferase activity|N-acetyltransferase activity|O-acyltransferase activity|palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity|carnitine O-acyltransferase activity|acetyltransferase activity|C-acyltransferase activity|palmitoyltransferase activity|N-acyltransferase activity|acylglycerol O-acyltransferase activity|serine O-acyltransferase activity|serine O-acyltransferase activity|O-acetyltransferase activity|O-octanoyltransferase activity|octanoyltransferase activity|O-palmitoyltransferase activity|S-acyltransferase activity|S-acetyltransferase activity|S-malonyltransferase activity|malonyltransferase activity|C-palmitoyltransferase activity|transferase activity|transferase activity, transferring acyl groups|succinyltransferase activity|N-succinyltransferase activity|O-succinyltransferase activity|S-succinyltransferase activity|sinapoyltransferase activity|O-sinapoyltransferase activity|peptidyl-lysine N6-myristoyltransferase activity|peptidyl-lysine N6-palmitoyltransferase activity|benzoyl acetate-CoA thiolase activity|3-hydroxybutyryl-CoA thiolase activity|3-ketopimelyl-CoA thiolase activity|N-palmitoyltransferase activity|myristoyltransferase activity|acyl-CoA N-acyltransferase activity|protein-cysteine S-myristoyltransferase activity|protein-cysteine S-acyltransferase activity|dihydrolipoamide S-acyltransferase activity|glucosaminyl-phosphotidylinositol O-acyltransferase activity|ergosterol O-acyltransferase activity|lanosterol O-acyltransferase activity|naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity|2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity|2-methylhexanoyl-CoA C-acetyltransferase activity|butyryl-CoA 2-C-propionyltransferase activity|2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity|L-2-aminoadipate N-acetyltransferase activity|UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity|keto acid formate lyase activity|Ras palmitoyltransferase activity|azetidine-2-carboxylic acid acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity|",10,0,0,10,0.1,0.208,0.1,0.0501,0.0501,0.675,0,0,-1.3,1.7
ENSMUSG00000024957,KCNK4,"potassium channel, subfamily K, member 4",membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|potassium channel activity|,10,1.5,1.11,10,-0.2,1.17,-0.1,0.0497,-0.0497,0.675,0,0,-0.9,3
ENSMUSG00000029618,OCM,oncomodulin,nucleus|cytoplasm|protein complex|,cytosolic calcium ion homeostasis|,calcium ion binding|protein homodimerization activity|metal ion binding|protein heterodimerization activity|,10,-0.2,0.487,10,1,1.49,-0.1,0.0495,-0.0495,0.675,0,0,-0.8,2
ENSMUSG00000027703,LRRIQ4,leucine-rich repeats and IQ motif containing 4,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.081,10,0,0,-0.1,0.0485,-0.0485,0.676,0,0,-1.7,1.2
ENSMUSG00000049548,KRT82,keratin 82,intermediate filament|keratin filament|,biological_process|,structural molecule activity|,10,0,0,10,-0.1,0.126,-0.1,0.0482,-0.0482,0.676,0,0,-1.7,1.2
ENSMUSG00000078926,CDC20B,cell division cycle 20B,cellular_component|,biological_process|,molecular_function|,10,0.1,0.297,10,0,0,0.1,0.0476,0.0476,0.677,0,0,-1.2,1.7
ENSMUSG00000027530,FABP12,fatty acid binding protein 12,cellular_component|,transport|biological_process|,transporter activity|lipid binding|,10,0.4,1.17,10,0,0,0.1,0.0475,0.0475,0.677,0,0,-0.9,1.9
ENSMUSG00000059429,OLFR365,olfactory receptor 365,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.183,10,0,0,-0.1,0.0453,-0.0453,0.678,0,0,-1.8,1.1
ENSMUSG00000073295,NUDT11,nudix (nucleoside diphosphate linked moiety X)-type motif 11,intracellular|,None,diphosphoinositol-polyphosphate diphosphatase activity|,10,0,0,10,-0.1,0.102,-0.1,0.0424,-0.0424,0.68,0,0,-1.8,1.2
ENSMUSG00000042846,LRRTM3,leucine rich repeat transmembrane neuronal 3,plasma membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,positive regulation of beta-amyloid formation|positive regulation of beta-amyloid formation|,molecular_function|,10,0.1,0.0389,10,0.1,0.0077,0.1,0.0423,0.0423,0.68,0,0,-1.6,1.4
ENSMUSG00000067594,KRT77,keratin 77,cytoskeleton|intermediate filament|keratin filament|,None,structural molecule activity|,10,-0.2,0.537,10,0,0,-0.1,0.0414,-0.0414,0.68,0,0,-1.4,1.5
ENSMUSG00000090176,CD200R2,Cd200 receptor 2,external side of plasma membrane|membrane|integral component of membrane|,None,receptor activity|protein binding|,10,0.1,0.316,10,-0.2,0.62,-0.1,0.0412,-0.0412,0.68,0,0,-1.4,1.4
ENSMUSG00000075168,OLFR1099,olfactory receptor 1099,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.2,0.536,-0.1,0.0409,-0.0409,0.68,0,0,-1.7,1.2
ENSMUSG00000034871,FAM151A,"family with sequence simliarity 151, member A",membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0.2,0.654,0.1,0.0408,0.0408,0.68,0,0,-1.2,1.7
ENSMUSG00000047511,OLFR1396,olfactory receptor 1396,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1,1.52,10,0.1,0.0837,0.1,0.0404,0.0404,0.681,0,0,-2,0.8
ENSMUSG00000009075,CABP7,calcium binding protein 7,cytoplasm|Golgi apparatus|plasma membrane|membrane|integral component of membrane|trans-Golgi network membrane|trans-Golgi network membrane|,biological_process|,calcium ion binding|metal ion binding|,10,0.7,1.55,10,-0.4,0.396,0.3,0.0354,0.0354,0.683,0,0,-1.3,1.8
ENSMUSG00000039628,HS3ST6,heparan sulfate (glucosamine) 3-O-sulfotransferase 6,cellular_component|Golgi apparatus|membrane|integral component of membrane|,None,sulfotransferase activity|[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity|transferase activity|,10,-1.1,1.36,10,0.2,0.0263,-0.1,0.0352,-0.0352,0.683,0,0,-2,0.8
ENSMUSG00000078949,R3HDML,R3H domain containing-like,cellular_component|extracellular region|,biological_process|negative regulation of peptidase activity|,molecular_function|peptidase inhibitor activity|,10,0,0,10,-0.1,0.289,-0.1,0.0337,-0.0337,0.684,0,0,-1.6,1.4
ENSMUSG00000044292,OLFR978,olfactory receptor 978,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.2,0.406,0.1,0.0335,0.0335,0.684,0,0,-1.3,1.6
ENSMUSG00000030351,TSPAN11,tetraspanin 11,membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.357,10,0,0,-0.1,0.0334,-0.0334,0.684,0,0,-1.5,1.5
ENSMUSG00000031230,FGF16,fibroblast growth factor 16,extracellular region|,fibroblast growth factor receptor signaling pathway|positive regulation of brown fat cell proliferation|,receptor binding|fibroblast growth factor receptor binding|growth factor activity|,10,0.2,0.441,10,0,0,0.1,0.0328,0.0328,0.685,0,0,-0.9,1.8
ENSMUSG00000061835,OLFR316,olfactory receptor 316,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.238,10,0,0,0.1,0.0317,0.0317,0.686,0,0,-1.4,1.6
ENSMUSG00000021728,EMB,embigin,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|synapse|,cell adhesion|plasma membrane lactate transport|,None,10,-0.2,0.0484,10,-0.1,0.0752,-0.1,0.0314,-0.0314,0.686,0,0,-1.7,1.1
ENSMUSG00000028963,UTS2,urotensin 2,extracellular region|extracellular space|,"negative regulation of glomerular filtration|positive regulation of cytosolic calcium ion concentration|regulation of blood pressure|negative regulation of heart rate|positive regulation of heart rate|positive regulation of fibroblast migration|positive regulation of circadian sleep/wake cycle, wakefulness|positive regulation of synaptic transmission, cholinergic|positive regulation of collagen biosynthetic process|negative regulation of urine volume|negative regulation of renal sodium excretion|regulation of vasodilation|positive regulation of cell differentiation|positive regulation of angiogenesis|negative regulation of blood pressure|positive regulation of blood pressure|positive regulation of vasodilation|positive regulation of circadian sleep/wake cycle, REM sleep|negative regulation of insulin secretion|positive regulation of fibroblast proliferation|",hormone activity|,10,0.2,0.651,10,0,0,0.1,0.0296,0.0296,0.687,0,0,-1.2,1.7
ENSMUSG00000027409,1700020A23RIK,RIKEN cDNA 1700020A23 gene,cellular_component|,biological_process|,molecular_function|,9,-0.1,0.0224,10,-0.1,0.00986,-0.1,0.0294,-0.0294,0.687,0,0,-1,2
ENSMUSG00000051896,TEX37,testis expressed 37,cellular_component|nucleus|,biological_process|,molecular_function|,10,-0.1,0.379,10,0,0,-0.1,0.0292,-0.0292,0.687,0,0,-1.7,1.3
ENSMUSG00000021388,ASPN,asporin,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|integral component of membrane|extracellular matrix|pore complex|,transport|ion transport|bone mineralization|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|biomineral tissue development|negative regulation of tooth mineralization|,calcium ion binding|protein binding|collagen binding|porin activity|,10,0.2,0.768,10,-0.1,0.19,0.1,0.0285,0.0285,0.687,0,0,-1.3,1.6
ENSMUSG00000047531,RTP2,receptor transporter protein 2,plasma membrane|cell surface|membrane|integral component of membrane|,protein insertion into membrane|,olfactory receptor binding|,10,0,0,10,-0.2,0.519,-0.1,0.0234,-0.0234,0.69,0,0,-1.5,1.5
ENSMUSG00000051190,OLFR1356,olfactory receptor 1356,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0224,10,-0.1,0.00323,-0.1,0.0233,-0.0233,0.69,0,0,-1.5,1.5
ENSMUSG00000053318,SLAMF8,SLAM family member 8,intracellular|membrane|integral component of membrane|,regulation of NAD(P)H oxidase activity|cellular response to drug|defense response to bacterium|regulation of kinase activity|phagosome acidification|,molecular_function|receptor activity|,10,-0.2,0.668,10,0,0,-0.1,0.0206,-0.0206,0.691,0,0,-1.5,1.4
ENSMUSG00000050010,SHISA3,shisa family member 3,endoplasmic reticulum|membrane|integral component of membrane|,multicellular organismal development|,None,10,0,0,10,0.1,0.113,0.1,0.0205,0.0205,0.692,0,0,-1.1,1.8
ENSMUSG00000032313,AI118078,expressed sequence AI118078,plasma membrane|membrane|integral component of membrane|,regulation of ion transmembrane transport|calcium ion import|membrane depolarization during action potential|,voltage-gated calcium channel activity|,10,-0.1,0.0372,10,0,0,-0.1,0.0192,-0.0192,0.692,0,0,-1.7,1.3
ENSMUSG00000022103,GFRA2,glial cell line derived neurotrophic factor family receptor alpha 2,plasma membrane|membrane|anchored component of membrane|,transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|cytokine-mediated signaling pathway|negative regulation of protein autophosphorylation|glial cell-derived neurotrophic factor receptor signaling pathway|,receptor activity|glial cell-derived neurotrophic factor receptor activity|,10,0,0,10,-0.1,0.152,-0.1,0.018,-0.018,0.693,0,0,-1.7,1.2
ENSMUSG00000049692,TMEM239,transmembrane 239,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.121,10,0,0,0.1,0.017,0.017,0.694,0,0,-1.2,1.7
ENSMUSG00000043102,QRFP,pyroglutamylated RFamide peptide,extracellular region|,neuropeptide signaling pathway|grooming behavior|locomotory behavior|positive regulation of blood pressure|regulation of feeding behavior|,G-protein coupled receptor binding|neuropeptide hormone activity|orexigenic neuropeptide QRFP receptor binding|,10,-0.2,0.795,10,0.1,0.0862,0.1,0.0163,0.0163,0.694,0,0,-1.3,1.7
ENSMUSG00000043782,CCDC64B,coiled-coil domain containing 64B,cellular_component|,biological_process|,Rab GTPase binding|,10,0.1,0.0909,10,0,0,0.1,0.0158,0.0158,0.694,0,0,-1.7,1.5
ENSMUSG00000042793,LGR6,leucine-rich repeat-containing G protein-coupled receptor 6,plasma membrane|membrane|integral component of membrane|vesicle|,signal transduction|G-protein coupled receptor signaling pathway|Wnt signaling pathway|positive regulation of Wnt signaling pathway|positive regulation of cell migration|,molecular_function|signal transducer activity|G-protein coupled receptor activity|protein-hormone receptor activity|,10,-0.4,0.539,10,0.2,0.652,0.1,0.0155,0.0155,0.695,0,0,-1.6,1.3
ENSMUSG00000059504,OLFR314,olfactory receptor 314,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.133,10,0,0,0.1,0.0154,0.0154,0.695,0,0,-1.2,1.8
ENSMUSG00000015085,ENTPD2,ectonucleoside triphosphate diphosphohydrolase 2,basal lamina|plasma membrane|membrane|integral component of membrane|,G-protein coupled receptor signaling pathway|purine ribonucleoside diphosphate catabolic process|platelet activation|,"nucleotide binding|thiamine-pyrophosphatase activity|protein binding|ATP binding|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|nucleoside-diphosphatase activity|nucleoside-triphosphatase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|",10,-0.1,0.234,10,0.1,0.0649,0.1,0.015,0.015,0.695,0,0,-1.1,1.8
ENSMUSG00000029088,KCNIP4,Kv channel interacting protein 4,plasma membrane|membrane|dendrite|neuronal cell body|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|potassium channel activity|calcium ion binding|metal ion binding|,10,0,0,10,-0.1,0.126,0.1,0.0126,0.0126,0.696,0,0,-1.3,1.6
ENSMUSG00000036244,TBC1D21,"TBC1 domain family, member 21",acrosomal vesicle|extracellular vesicular exosome|,biological_process|,actin binding|,10,-0.1,0.118,10,0,0,-0.1,0.012,-0.012,0.697,0,0,-1.5,1.5
ENSMUSG00000045573,PENK,preproenkephalin,extracellular region|,behavioral fear response|startle response|aggressive behavior|neuropeptide signaling pathway|locomotory behavior|sensory perception of pain|,opioid peptide activity|,10,0,0,10,-0.1,0.049,-0.1,0.012,-0.012,0.697,0,0,-1.7,1.3
ENSMUSG00000035148,GPR33,G protein-coupled receptor 33,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.5,2.07,10,0,0,-0.3,0.00785,-0.00785,0.699,0,0,-2,0.6
ENSMUSG00000043418,LRIT2,"leucine-rich repeat, immunoglobulin-like and transmembrane domains 2",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.384,-0.1,0.00704,-0.00704,0.7,0,0,-1.3,1.6
ENSMUSG00000004709,CD244,CD244 natural killer cell receptor 2B4,external side of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,None,receptor activity|protein binding|,10,0.1,0.0426,10,-0.1,0.193,0.1,0.00481,0.00481,0.701,0,0,-0.9,1.9
ENSMUSG00000033383,RTP1,receptor transporter protein 1,plasma membrane|cell surface|membrane|integral component of membrane|,protein insertion into membrane|,olfactory receptor binding|,10,0.9,2.02,10,-0.1,0.0474,0.1,0.00429,0.00429,0.701,0,0,-0.7,2
ENSMUSG00000057899,GPR111,G protein-coupled receptor 111,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0798,0.1,0.00372,0.00372,0.702,0,0,-1.3,1.6
ENSMUSG00000022650,RETNLB,resistin like beta,extracellular region|,None,hormone activity|,10,0,0,10,0.1,0.017,0.1,0.00356,0.00356,0.702,0,0,-1.1,1.8
ENSMUSG00000046613,VWA5B2,von Willebrand factor A domain containing 5B2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.11,-0.1,0.00317,-0.00317,0.702,0,0,-1.8,1.1
ENSMUSG00000073102,DRC1,dynein regulatory complex subunit 1,cellular_component|cytoplasm|cytoskeleton|cilium|cell projection|,cilium-dependent cell motility|axonemal dynein complex assembly|bacterial-type flagellum-dependent cell motility|,molecular_function|,10,0.1,0.164,10,0,0,0.1,0.00251,0.00251,0.702,0,0,-1.3,1.6
ENSMUSG00000033467,CRLF2,cytokine receptor-like factor 2,extracellular region|cell|plasma membrane|membrane|integral component of membrane|,immunoglobulin secretion involved in immune response|inflammatory response|T-helper 2 cell cytokine production|,cytokine activity|,10,-0.9,1.17,10,0.1,0.225,-0.1,0.00246,-0.00246,0.703,0,0,-2,0.7
ENSMUSG00000095075,OLFR782,olfactory receptor 782,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,6,-0.2,0.411,6,0,0,-0.1,0.000743,-0.000743,0.704,0,0,-1.7,1.6
ENSMUSG00000029248,1700023E05RIK,RIKEN cDNA 1700023E05 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.00082,10,0,0,-0.1,0.000358,-0.000358,0.704,0,0,-1.9,1
ENSMUSG00000070942,IL1RL2,interleukin 1 receptor-like 2,cellular_component|membrane|integral component of membrane|,signal transduction|cytokine-mediated signaling pathway|positive regulation of interleukin-6 production|positive regulation of T cell differentiation|regulation of inflammatory response|,"cytokine receptor activity|interleukin-1 receptor activity|interleukin-1, Type I, activating receptor activity|",10,0,0,10,0.1,0.197,0.1,0.000256,0.000256,0.704,0,0,-1.5,1.5
ENSMUSG00000066383,IQCF1,IQ motif containing F1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000024109,NRXN1,neurexin I,cell|plasma membrane|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|cell junction|endocytic vesicle|presynaptic membrane|synapse|,"vesicle docking involved in exocytosis|cell adhesion|synaptic transmission|neurotransmitter secretion|neurotransmitter secretion|synapse assembly|learning|learning|adult behavior|adult behavior|social behavior|vocal learning|neuromuscular process controlling balance|protein heterotetramerization|positive regulation of synapse assembly|positive regulation of synaptic transmission, glutamatergic|prepulse inhibition|regulation of insulin secretion involved in cellular response to glucose stimulus|vocalization behavior|positive regulation of synapse maturation|postsynaptic membrane assembly|gephyrin clustering|neuroligin clustering|postsynaptic density protein 95 clustering|positive regulation of excitatory postsynaptic membrane potential|regulation of grooming behavior|",receptor binding|calcium channel regulator activity|calcium ion binding|protein binding|acetylcholine receptor binding|metal ion binding|cell adhesion molecule binding|cell adhesion molecule binding|neuroligin family protein binding|neuroligin family protein binding|,10,0,0,10,0.1,0.0363,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000021872,RNASE10,"ribonuclease, RNase A family, 10 (non-active)",cellular_component|extracellular region|,epithelial cell morphogenesis|cell adhesion|single fertilization|male gonad development|positive regulation of cell-cell adhesion|heterotypic cell-cell adhesion|seminiferous tubule development|regulation of fertilization|positive regulation of sperm motility|,molecular_function|nucleic acid binding|,10,0.2,0.701,10,-0.2,0.307,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000043430,PSAPL1,prosaposin-like 1,extracellular region|lysosome|,lipid metabolic process|sphingolipid metabolic process|,molecular_function|,10,-0.1,0.0178,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000070366,PPAPDC1A,phosphatidic acid phosphatase type 2 domain containing 1A,cellular_component|membrane|integral component of membrane|,phospholipid dephosphorylation|,catalytic activity|phosphatidate phosphatase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000020286,1700093K21RIK,RIKEN cDNA 1700093K21 gene,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.065,10,0,0,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000026985,IL1F8,"interleukin 1 family, member 8",extracellular region|extracellular space|,positive regulation of cytokine production|inflammatory response|immune response|positive regulation of interleukin-6 production|positive regulation of T cell differentiation|,cytokine activity|interleukin-1 receptor binding|,10,-0.9,0.431,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000044103,IL1F9,"interleukin 1 family, member 9",extracellular region|extracellular space|,positive regulation of cytokine production|positive regulation of interleukin-6 production|,cytokine activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000096365,OLFR1463,olfactory receptor 1463,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000059610,OLFR222,olfactory receptor 222,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000063590,SLC22A28,"solute carrier family 22, member 28",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.2,0.292,0,0,0,0.704,0,0,-1,1.9
ENSMUSG00000033644,PIWIL2,piwi-like RNA-mediated gene silencing 2,cytoplasm|polysome|chromatoid body|P granule|pi-body|,RNA 5'-end processing|regulation of translation|meiotic nuclear division|multicellular organismal development|spermatogenesis|cell differentiation|germ-line stem cell maintenance|gene silencing by RNA|piRNA metabolic process|piRNA metabolic process|DNA methylation involved in gamete generation|positive regulation of translation|oogenesis|positive regulation of meiosis I|,nucleic acid binding|RNA binding|mRNA binding|protein binding|piRNA binding|piRNA binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000030909,ANKS4B,ankyrin repeat and sterile alpha motif domain containing 4B,endoplasmic reticulum membrane|plasma membrane|,response to endoplasmic reticulum stress|,protein binding|,10,0,0,10,0.1,0.044,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000046318,CCBE1,collagen and calcium binding EGF domains 1,extracellular region|collagen trimer|extracellular space|extracellular matrix|,angiogenesis|lymphangiogenesis|lymphangiogenesis|multicellular organismal development|positive regulation vascular endothelial growth factor production|positive regulation of endothelial cell migration|positive regulation of protein processing|positive regulation of angiogenesis|positive regulation of vascular endothelial growth factor signaling pathway|positive regulation of lymphangiogenesis|,protease binding|calcium ion binding|collagen binding|,10,0.1,0.00382,10,-0.1,0.165,0,0,0,0.704,0,0,-2,1
ENSMUSG00000027077,SMTNL1,smoothelin-like 1,nucleus|cytoplasm|M band|I band|contractile fiber|contractile fiber|,response to activity|peptidyl-serine phosphorylation|response to drug|negative regulation of catalytic activity|positive regulation of vasoconstriction|negative regulation of vasodilation|muscle organ morphogenesis|,protein phosphatase inhibitor activity|protein binding|calmodulin binding|protein phosphatase 1 binding|myosin phosphatase regulator activity|,10,0,0,10,-0.5,0.253,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000021086,CCDC175,coiled-coil domain containing 175,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.173,0,0,0,0.704,0,0,-1,1.9
ENSMUSG00000079436,KCNJ13,"potassium inwardly-rectifying channel, subfamily J, member 13",membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|,10,-0.1,0.0619,10,0,0,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000037627,RGS22,regulator of G-protein signalling 22,nucleus|cytoplasm|plasma membrane|,negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000019834,SLC22A16,"solute carrier family 22 (organic cation transporter), member 16",plasma membrane|membrane|integral component of membrane|,amino acid transmembrane transport|transport|ion transport|multicellular organismal development|spermatogenesis|single fertilization|organic cation transport|amine transport|carnitine transport|cell differentiation|sperm motility|acid secretion|transmembrane transport|modified amino acid transport|carnitine transmembrane transport|,amine transmembrane transporter activity|organic cation transmembrane transporter activity|carnitine transmembrane transporter activity|transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000058070,EML1,echinoderm microtubule associated protein like 1,cellular_component|cytoplasm|cytoskeleton|microtubule|,hematopoietic progenitor cell differentiation|brain development|,tubulin binding|,10,0.1,0.134,10,1,0.519,0,0,0,0.704,0,0,-0.7,2
ENSMUSG00000047129,1700113H08RIK,RIKEN cDNA 1700113H08 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.69,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000060212,PCNXL2,pecanex-like 2 (Drosophila),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.112,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000026894,MORN5,MORN repeat containing 5,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.217,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000043664,TMEM221,transmembrane protein 221,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000024784,GPHA2,glycoprotein hormone alpha 2,extracellular region|,biological_process|,molecular_function|hormone activity|,10,0.1,0.0533,10,0,0,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000047394,ODF3B,outer dense fiber of sperm tails 3B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.9
ENSMUSG00000050963,KCNS2,"K+ voltage-gated channel, subfamily S, 2",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000098188,SOWAHC,sosondowah ankyrin repeat domain family member C,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.296,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000039851,4932438H23RIK,RIKEN cDNA 4932438H23 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000072662,MANSC4,MANSC domain containing 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0128,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000044988,UCN3,urocortin 3,extracellular region|extracellular space|axon|neuron projection|varicosity|axon terminus|,response to stress|adenylate cyclase-activating G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|digestion|positive regulation of insulin secretion|positive regulation of membrane potential|,hormone activity|neuropeptide hormone activity|protein binding|corticotropin-releasing hormone receptor 2 binding|,10,0.1,0.489,10,-0.2,0.786,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000058275,OLFR412,olfactory receptor 412,intracellular|cell|plasma membrane|membrane|integral component of membrane|,"protein import into nucleus, translocation|signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|",signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.129,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000039533,MMD2,monocyte to macrophage differentiation-associated 2,Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|,cytolysis|,None,10,0,0,10,0.1,0.0644,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000070047,FAT1,FAT tumor suppressor homolog 1 (Drosophila),nucleus|plasma membrane|cell-cell junction|membrane|integral component of membrane|lamellipodium|cell junction|filopodium|perinuclear region of cytoplasm|extracellular vesicular exosome|,actin filament organization|cell adhesion|establishment or maintenance of cell polarity|single organismal cell-cell adhesion|,protein binding|,10,-0.1,0.186,10,0.4,0.998,0,0,0,0.704,0,0,-1.1,1.8
ENSMUSG00000071552,TIGIT,T cell immunoreceptor with Ig and ITIM domains,cell surface|,negative regulation of interleukin-12 production|positive regulation of interleukin-10 production|negative regulation of T cell activation|negative regulation of T cell activation|,receptor binding|receptor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000029359,TESC,tescalcin,ruffle|nucleus|nucleus|cytoplasm|cytoplasm|plasma membrane|membrane|lamellipodium|lamellipodium|cell projection|,"transport|cellular sodium ion homeostasis|negative regulation of cell proliferation|positive regulation of gene expression|protein transport|cell differentiation|positive regulation of granulocyte differentiation|positive regulation of sodium:proton antiporter activity|regulation of cell adhesion mediated by integrin|negative regulation of catalytic activity|positive regulation of megakaryocyte differentiation|positive regulation of transcription, DNA-templated|protein stabilization|protein maturation|cellular response to retinoic acid|protein targeting to plasma membrane|",magnesium ion binding|protein kinase inhibitor activity|calcium ion binding|calcium ion binding|phosphatase inhibitor activity|protein homodimerization activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000028259,FHL5,four and a half LIM domains 5,nucleus|,"transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|regulation of RNA biosynthetic process|",transcription coactivator activity|protein binding|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000030781,SLC5A2,"solute carrier family 5 (sodium/glucose cotransporter), member 2",membrane|integral component of membrane|brush border membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|carbohydrate transport|glucose transport|hexose transmembrane transport|sodium ion transmembrane transport|transmembrane transport|,transporter activity|glucose:sodium symporter activity|protein binding|symporter activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000054362,BC055111,cDNA sequence BC055111,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.361,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000051509,OLFR414,olfactory receptor 414,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0199,10,-0.1,0.0268,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000057767,OLFR1383,olfactory receptor 1383,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.0937,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000019842,TRAF3IP2,TRAF3 interacting protein 2,cell|,B cell apoptotic process|humoral immune response|immunoglobulin secretion|,protein binding|,10,-0.1,0.0344,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000023993,TREML1,triggering receptor expressed on myeloid cells-like 1,cytoplasm|plasma membrane|cell surface|cell surface|membrane|integral component of membrane|platelet alpha granule|platelet alpha granule|,negative regulation of signal transduction|calcium-mediated signaling|wound healing|,receptor activity|protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000075089,OLFR1238,olfactory receptor 1238,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.209,10,0.3,0.36,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000040978,GM11992,predicted gene 11992,cellular_component|,biological_process|,molecular_function|,10,-1,0.292,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000094282,CCDC42B,coiled-coil domain containing 42B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000031258,XKRX,X Kell blood group precursor related X linked,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0224,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000026765,LYPD6B,LY6/PLAUR domain containing 6B,cellular_component|plasma membrane|membrane|anchored component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000034063,4930590J08RIK,RIKEN cDNA 4930590J08 gene,cytoplasm|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.3,1.18,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000024246,THUMPD2,THUMP domain containing 2,cellular_component|,biological_process|methylation|,molecular_function|RNA binding|methyltransferase activity|transferase activity|,10,0.1,0.504,10,0,0,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000048022,TMEM229A,transmembrane protein 229A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.213,10,0,0,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000044217,AQP5,aquaporin 5,endoplasmic reticulum|plasma membrane|integral component of plasma membrane|microvillus|basal plasma membrane|membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|extracellular vesicular exosome|,transport|water transport|water transport|water transport|carbon dioxide transport|saliva secretion|camera-type eye morphogenesis|transmembrane transport|,transporter activity|protein binding|water channel activity|water channel activity|,10,0.2,0.518,10,0,0,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000025333,GPR143,G protein-coupled receptor 143,cell|lysosome|lysosomal membrane|Golgi apparatus|plasma membrane|membrane|integral component of membrane|apical plasma membrane|melanosome membrane|melanosome|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|melanosome localization|melanosome localization|melanosome transport|melanosome transport|melanosome organization|melanosome organization|calcium-mediated signaling using intracellular calcium source|phosphatidylinositol-mediated signaling|regulation of calcium-mediated signaling|,signal transducer activity|G-protein coupled receptor activity|dopamine binding|L-DOPA receptor activity|L-DOPA binding|tyrosine binding|,10,0,0,10,0.2,0.308,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000052496,PKDREJ,"polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)",plasma membrane|,detection of mechanical stimulus|regulation of acrosome reaction|calcium ion transmembrane transport|,calcium channel activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000049109,THEMIS,thymocyte selection associated,nucleus|cytoplasm|cell-cell junction|COP9 signalosome|,immune system process|multicellular organismal development|positive T cell selection|negative T cell selection|T cell receptor signaling pathway|,protein binding|,10,0.2,0.711,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000052212,CD177,CD177 antigen,cellular_component|plasma membrane|membrane|anchored component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.173,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000027848,OLFML3,olfactomedin-like 3,cellular_component|extracellular region|,multicellular organismal development|biological_process|,molecular_function|,10,-0.6,1.7,10,0,0,0,0,0,0.704,0,0,-2,0.7
ENSMUSG00000021538,IL9,interleukin 9,extracellular region|extracellular space|,immune response|positive regulation of cell growth|positive regulation of interleukin-5 biosynthetic process|,cytokine activity|cytokine receptor binding|interleukin-9 receptor binding|growth factor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000039546,AJAP1,adherens junction associated protein 1,cellular_component|plasma membrane|membrane|integral component of membrane|cell junction|,cell adhesion|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000042849,OLFR1414,olfactory receptor 1414,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,0.546,10,0.1,0.16,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000092021,GBP11,guanylate binding protein 11,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.3,0.0255,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000054161,FAM83E,"family with sequence similarity 83, member E",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.3,0.573,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000059023,OLFR1201,olfactory receptor 1201,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.364,10,-0.1,0.132,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000035020,EPGN,epithelial mitogen,intracellular|integral component of plasma membrane|membrane|integral component of membrane|,MAPK cascade|activation of MAPK activity|angiogenesis|protein phosphorylation|positive regulation of cell proliferation|positive regulation of MAP kinase activity|positive regulation of epidermal growth factor-activated receptor activity|positive regulation of epidermal growth factor-activated receptor activity|positive regulation of mitosis|positive regulation of mitosis|positive regulation of epithelial cell proliferation|,MAP kinase kinase activity|epidermal growth factor receptor binding|epidermal growth factor receptor binding|growth factor activity|growth factor activity|,10,-0.1,0.056,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000029678,HYAL5,hyaluronoglucosaminidase 5,acrosomal vesicle|plasma membrane|external side of plasma membrane|,penetration of zona pellucida|metabolic process|,"hyalurononglucosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.7,0.318,10,-0.2,0.312,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000021799,OPN4,opsin 4 (melanopsin),plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|visual perception|phototransduction|phototransduction|detection of visible light|rhodopsin mediated signaling pathway|protein-chromophore linkage|regulation of circadian rhythm|rhythmic process|response to stimulus|,signal transducer activity|G-protein coupled receptor activity|11-cis retinal binding|G-protein coupled photoreceptor activity|G-protein coupled photoreceptor activity|G-protein coupled photoreceptor activity|photoreceptor activity|,10,0.1,0.118,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000049350,ZG16,zymogen granule protein 16,extracellular region|proteinaceous extracellular matrix|Golgi apparatus|Golgi lumen|extracellular matrix|cytoplasmic vesicle|zymogen granule membrane|,transport|biological_process|protein transport|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000074361,C5AR2,complement component 5a receptor 2,plasma membrane|basal plasma membrane|membrane|integral component of membrane|apical part of cell|,chemotaxis|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|negative regulation of tumor necrosis factor production|positive regulation of epithelial cell proliferation|positive regulation of ERK1 and ERK2 cascade|negative regulation of neutrophil chemotaxis|negative regulation of interleukin-6 secretion|regulation of interleukin-8 secretion|,signal transducer activity|G-protein coupled receptor activity|C5a anaphylatoxin receptor activity|,10,-0.1,0.102,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000048281,DLEU7,"deleted in lymphocytic leukemia, 7",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.7
ENSMUSG00000056133,GM9992,predicted gene 9992,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000073914,OLFR677,olfactory receptor 677,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.6,0.807,10,0,0,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000078253,KRTAP16-1,keratin associated protein 16-1,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000045091,AQP12,aquaporin 12,cytoplasm|membrane|integral component of membrane|,transport|,transporter activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.9,1.2
ENSMUSG00000019815,ZC2HC1B,"zinc finger, C2HC-type containing 1B",cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,-0.2,0.574,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000027316,GFRA4,glial cell line derived neurotrophic factor family receptor alpha 4,extracellular region|extracellular space|plasma membrane|membrane|anchored component of membrane|extracellular vesicular exosome|,transmembrane receptor protein tyrosine kinase signaling pathway|cytokine-mediated signaling pathway|negative regulation of ossification|glial cell-derived neurotrophic factor receptor signaling pathway|,receptor activity|coreceptor activity|glial cell-derived neurotrophic factor receptor activity|,10,0,0,10,0.1,0.222,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000054141,OLFR24,olfactory receptor 24,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000054901,ARHGEF33,Rho guanine nucleotide exchange factor (GEF) 33,cellular_component|,biological_process|regulation of Rho protein signal transduction|,molecular_function|guanyl-nucleotide exchange factor activity|Rho guanyl-nucleotide exchange factor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000049409,PROKR1,prokineticin receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|circadian rhythm|negative regulation of apoptotic process|coronary vasculature development|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000010311,OPTC,opticin,extracellular region|proteinaceous extracellular matrix|extracellular matrix|,negative regulation of angiogenesis|,molecular_function|,10,0,0,10,-0.4,0.421,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000030235,SLCO1C1,"solute carrier organic anion transporter family, member 1c1",plasma membrane|membrane|integral component of membrane|,transport|ion transport|lipid transport|bile acid and bile salt transport|ion transmembrane transport|,transporter activity|bile acid transmembrane transporter activity|,10,0.1,0.203,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000052485,TMEM171,transmembrane protein 171,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0171,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000042861,KCNA10,"potassium voltage-gated channel, shaker-related subfamily, member 10",plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.1,0.203,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000078815,CACNG6,"calcium channel, voltage-dependent, gamma subunit 6",membrane|integral component of membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|,voltage-gated ion channel activity|calcium channel activity|,10,0,0,10,-0.3,0.227,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000075567,KRTAP1-4,keratin associated protein 1-4,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.1,0.115,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000051726,KCNF1,"potassium voltage-gated channel, subfamily F, member 1",voltage-gated potassium channel complex|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,0.1,0.157,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000047230,CLDN2,claudin 2,plasma membrane|tight junction|membrane|integral component of membrane|cell junction|extracellular vesicular exosome|,calcium-independent cell-cell adhesion|,structural molecule activity|protein binding|identical protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000045708,OLFR447,olfactory receptor 447,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.272,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000075380,OLFR355,olfactory receptor 355,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.482,10,0,0,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000020121,SRGAP1,SLIT-ROBO Rho GTPase activating protein 1,intracellular|,signal transduction|Rho protein signal transduction|cell migration|positive regulation of Rho GTPase activity|,GTPase activator activity|Rho GTPase activator activity|protein binding|Rho GTPase binding|,10,0.1,0.173,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000079583,GM7073,predicted gene 7073,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.231,10,0.8,2.9,0,0,0,0.704,0,0,-0.7,2
ENSMUSG00000046280,SHE,src homology 2 domain-containing transforming protein E,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000025652,TMEM89,transmembrane protein 89,nucleus|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0,0,9,0,0,0,0,0,0.704,0,0,-1.7,1.5
ENSMUSG00000094192,OLFR452,olfactory receptor 452,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.4,0.556,0,0,0,0.704,0,0,-1.9,1
ENSMUSG00000050742,OLFR164,olfactory receptor 164,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.198,10,0.2,0.344,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000096773,OLFR675,olfactory receptor 675,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0786,10,0,0,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000091530,CLDN20,claudin 20,cellular_component|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000050777,TMEM37,transmembrane protein 37,membrane|integral component of membrane|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|,voltage-gated ion channel activity|calcium channel activity|,10,0,0,10,0.2,0.217,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000035238,KCNK15,"potassium channel, subfamily K, member 15",cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,None,10,0.1,0.156,10,0,0,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000052382,RNASE9,"ribonuclease, RNase A family, 9 (non-active)",cellular_component|extracellular region|,biological_process|,molecular_function|nucleic acid binding|,10,0.1,0.0295,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000096215,SMIM22,small integral membrane protein 22,cellular_component|,biological_process|,molecular_function|,9,0,0,9,0.1,0.0387,0,0,0,0.704,0,0,-1.5,1.7
ENSMUSG00000038756,TTLL6,"tubulin tyrosine ligase-like family, member 6",cytoplasm|cytoskeleton|cilium|ciliary basal body|cell projection|,microtubule bundle formation|positive regulation of cilium movement|cellular protein modification process|protein polyglutamylation|microtubule severing|microtubule severing|,tubulin binding|ligase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000049809,KRTAP9-3,keratin associated protein 9-3,cellular_component|intermediate filament|keratin filament|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000037469,PAPL,iron/zinc purple acid phospatase-like,cellular_component|extracellular region|,biological_process|,acid phosphatase activity|hydrolase activity|metal ion binding|,10,0.6,0.723,10,0,0,0,0,0,0.704,0,0,-0.8,2
ENSMUSG00000090129,OLFR287,olfactory receptor 287,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.897,10,0.2,0.985,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000020916,KRT36,keratin 36,intermediate filament|intermediate filament cytoskeleton|,regulation of keratinocyte differentiation|,structural molecule activity|structural constituent of epidermis|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000090314,2310050C09RIK,RIKEN cDNA 2310050C09 gene,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.316,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000062608,OLFR195,olfactory receptor 195,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000045348,NYAP1,neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1,intracellular|,phosphatidylinositol 3-kinase signaling|neuron projection morphogenesis|,protein binding|,10,-0.1,0.182,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000057816,1700007G11RIK,RIKEN cDNA 1700007G11 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.103,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000027416,OTOR,otoraplin,extracellular region|Golgi apparatus|,cartilage condensation|,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000038916,SOGA3,SOGA family member 3,cellular_component|extracellular space|membrane|integral component of membrane|,biological_process|regulation of autophagy|,molecular_function|,10,0.1,0.271,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000078442,CCDC105,coiled-coil domain containing 105,extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000078354,IFNA2,interferon alpha 2,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,10,-0.1,0.166,10,0,0,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000001943,VSIG2,V-set and immunoglobulin domain containing 2,integral component of plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.118,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000024302,DTNA,dystrobrevin alpha,cytoplasm|plasma membrane|dystrobrevin complex|membrane|cell junction|axon|extrinsic component of cytoplasmic side of plasma membrane|sarcolemma|sarcolemma|cell projection|protein complex|synapse|,None,calcium ion binding|protein binding|zinc ion binding|PDZ domain binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000046493,OLFR1352,olfactory receptor 1352,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.2,0.514,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000054404,SLFN5,schlafen 5,nucleus|,cell differentiation|,nucleotide binding|ATP binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000035189,ANO4,anoctamin 4,intracellular|plasma membrane|membrane|integral component of membrane|,chloride transport|phospholipid transport|calcium activated phosphatidylserine scrambling|calcium activated phosphatidylcholine scrambling|calcium activated galactosylceramide scrambling|chloride transmembrane transport|,phospholipid scramblase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000040759,CMTM5,CKLF-like MARVEL transmembrane domain containing 5,cellular_component|extracellular space|membrane|integral component of membrane|,chemotaxis|biological_process|,molecular_function|cytokine activity|,10,0,0,10,-0.2,0.252,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000026983,IL1F5,"interleukin 1 family, member 5 (delta)",extracellular region|extracellular space|,negative regulation of interleukin-6 production|,molecular_function|cytokine activity|interleukin-1 receptor binding|interleukin-1 receptor antagonist activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000064129,GM14781,predicted gene 14781,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000070877,LDLRAD1,low density lipoprotein receptor class A domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.325,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000022798,4930435E12RIK,RIKEN cDNA 4930435E12 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000050854,TMEM125,transmembrane protein 125,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000046080,CLEC9A,"C-type lectin domain family 9, member a",cell surface|cell surface|membrane|integral component of membrane|,receptor-mediated endocytosis|receptor-mediated endocytosis|positive regulation of cytokine secretion|,carbohydrate binding|,10,-0.3,0.136,10,0.1,0.0156,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000075066,OLFR32,olfactory receptor 32,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.2,0.517,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000098049,GBP11,guanylate binding protein 11,extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.1,0.213,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000050157,GM867,predicted gene 867,cellular_component|,biological_process|,molecular_function|,9,0,0,9,0.3,0.822,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000049057,OLFR1257,olfactory receptor 1257,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.2,0.0211,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000031709,TBC1D9,"TBC1 domain family, member 9",cellular_component|,biological_process|regulation of Rab GTPase activity|,molecular_function|GTPase activator activity|Rab GTPase activator activity|calcium ion binding|,10,0,0,9,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000036502,TMEM255A,transmembrane protein 255A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.146,10,0,0,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000018634,CRHR1,corticotropin releasing hormone receptor 1,cell|endosome|multivesicular body|trans-Golgi network|plasma membrane|membrane|integral component of membrane|dendrite|intrinsic component of plasma membrane|vesicle|neuronal cell body|apical part of cell|,"response to hypoxia|signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|memory|visual learning|hormone-mediated signaling pathway|regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|adrenal gland development|positive regulation of cAMP biosynthetic process|epithelial cell differentiation|negative regulation of epinephrine secretion|locomotory exploration behavior|fear response|positive regulation of mast cell degranulation|behavioral response to cocaine|behavioral response to ethanol|regulation of synaptic plasticity|behavioral response to pain|corticotropin secretion|response to electrical stimulus|general adaptation syndrome, behavioral process|long-term synaptic potentiation|cellular response to corticotropin-releasing hormone stimulus|cellular response to corticotropin-releasing hormone stimulus|negative regulation of neuron death|negative regulation of voltage-gated calcium channel activity|negative regulation of feeding behavior|regulation of corticosterone secretion|",G-protein alpha-subunit binding|signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|corticotrophin-releasing factor receptor activity|corticotrophin-releasing factor receptor activity|protein complex binding|peptide binding|corticotropin-releasing hormone receptor activity|corticotropin-releasing hormone binding|,10,-0.8,0.148,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000041616,NPPA,natriuretic peptide type A,extracellular region|extracellular space|nucleus|cytoplasm|cytoplasm|mast cell granule|perinuclear region of cytoplasm|,negative regulation of systemic arterial blood pressure|cGMP biosynthetic process|receptor guanylyl cyclase signaling pathway|female pregnancy|regulation of blood pressure|regulation of blood pressure|cardiac muscle hypertrophy in response to stress|negative regulation of cell growth|regulation of blood vessel size|,receptor binding|hormone activity|peptide hormone receptor binding|,10,0.2,0.197,10,0,0,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000063120,OLFR480,olfactory receptor 480,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.5,0.703,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000048399,TPRG,transformation related protein 63 regulated,cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0.6,0.578,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000092083,KCNB2,"potassium voltage gated channel, Shab-related subfamily, member 2",voltage-gated potassium channel complex|membrane|integral component of membrane|neuronal cell body|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.1,0.151,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000091455,OTOGL,otogelin-like,cellular_component|extracellular region|,biological_process|L-arabinose metabolic process|,molecular_function|alpha-L-arabinofuranosidase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000041012,CMTM8,CKLF-like MARVEL transmembrane domain containing 8,cellular_component|extracellular space|membrane|integral component of membrane|,chemotaxis|biological_process|,molecular_function|cytokine activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000095789,NUPR1L,nuclear protein transcriptional regulator 1 like,cellular_component|,biological_process|,molecular_function|,10,0.2,0.464,10,-0.2,0.446,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000095401,OLFR804,olfactory receptor 804,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.1,0.177,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000096257,GM6537,predicted gene 6537,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.276,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000031147,MAGIX,"MAGI family member, X-linked",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000095002,OLFR798,olfactory receptor 798,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000041138,NME8,NME/NM23 family member 8,cytoplasm|,nucleoside diphosphate phosphorylation|GTP biosynthetic process|UTP biosynthetic process|CTP biosynthetic process|multicellular organismal development|spermatogenesis|cell differentiation|cell redox homeostasis|,nucleoside diphosphate kinase activity|ATP binding|,10,0.2,0.547,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000016982,POM121L2,POM121 membrane glycoprotein-like 2 (rat),cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000093973,MRGPRA2A,"MAS-related GPR, member A2A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.251,0,0,0,0.704,0,0,-1.8,1.4
ENSMUSG00000054497,TAS2R130,"taste receptor, type 2, member 130",cellular_component|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|bitter taste receptor activity|,10,-1.2,1.38,10,0.1,0.00264,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000050122,VWA3B,von Willebrand factor A domain containing 3B,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.169,10,0.3,0.816,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000027480,SUN5,Sad1 and UNC84 domain containing 5,cellular_component|nucleus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.00736,10,0.2,0.486,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000039257,VSTM2B,V-set and transmembrane domain containing 2B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.2,0.256,10,0,0,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000047822,GM6484,predicted gene 6484,extracellular region|,carbohydrate metabolic process|glucose metabolic process|lipid metabolic process|positive regulation of protein processing|regulation of lipid metabolic process|cellular lipid metabolic process|cellular lipid metabolic process|type B pancreatic cell proliferation|fat cell differentiation|cell maturation|regulation of lipoprotein metabolic process|negative regulation of lipoprotein lipase activity|triglyceride homeostasis|triglyceride homeostasis|triglyceride homeostasis|,hormone activity|,10,0.1,0.234,10,1,0.381,0,0,0,0.704,0,0,-1,2
ENSMUSG00000068392,RNASE13,"ribonuclease, RNase A family, 13 (non-active)",cellular_component|extracellular region|,biological_process|,molecular_function|nucleic acid binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000074199,KRTDAP,keratinocyte differentiation associated protein,extracellular region|,epidermis development|cell differentiation|,None,10,0,0,9,0,0,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000029602,RASAL1,RAS protein activator like 1 (GAP1 like),intracellular|cytoplasm|intrinsic component of the cytoplasmic side of the plasma membrane|,signal transduction|positive regulation of Ras GTPase activity|intracellular signal transduction|negative regulation of Ras protein signal transduction|regulation of small GTPase mediated signal transduction|,GTPase activator activity|Ras GTPase activator activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000019892,LRRIQ1,leucine-rich repeats and IQ motif containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000037157,IL22RA1,"interleukin 22 receptor, alpha 1",cellular_component|membrane|integral component of membrane|,defense response to Gram-negative bacterium|,interleukin-20 binding|,10,0.2,0.908,10,-0.1,0.103,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000051593,OLFR272,olfactory receptor 272,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000070563,SPACA4,sperm acrosome associated 4,cellular_component|plasma membrane|membrane|anchored component of membrane|cytoplasmic vesicle|,cell adhesion|biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000056423,UTS2B,urotensin 2B,extracellular region|,regulation of blood pressure|regulation of vasodilation|,G-protein coupled receptor binding|hormone activity|,10,-1.3,2.82,10,0.2,0.764,0,0,0,0.704,0,0,-2,0.6
ENSMUSG00000070802,PNMAL2,PNMA-like 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.00352,0,0,0,0.704,0,0,-0.8,1.9
ENSMUSG00000049528,OLFR429,olfactory receptor 429,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.179,10,-0.1,0.276,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000049630,C1QL3,C1q-like 3,extracellular region|collagen trimer|,regulation of synapse organization|,protein binding|,10,0,0,10,-0.2,0.155,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000049491,SLC36A3,"solute carrier family 36 (proton/amino acid symporter), member 3",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.487,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000055820,OLFR967,olfactory receptor 967,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000053044,CD8B1,"CD8 antigen, beta chain 1",external side of plasma membrane|cell surface|membrane|integral component of membrane|,immune system process|,protein binding|,10,0,0,10,0.2,0.355,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000096719,MRGPRA2B,"MAS-related GPR, member A2B",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.9
ENSMUSG00000025978,RFTN2,raftlin family member 2,cellular_component|plasma membrane|membrane|,dsRNA transport|response to exogenous dsRNA|,molecular_function|,10,0,0,10,0.9,0.714,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000040505,ABCG5,"ATP-binding cassette, sub-family G (WHITE), member 5",membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|apical part of cell|,ATP catabolic process|transport|excretion|excretion|negative regulation of intestinal phytosterol absorption|intestinal cholesterol absorption|cholesterol efflux|cholesterol efflux|cholesterol homeostasis|negative regulation of intestinal cholesterol absorption|,nucleotide binding|ATP binding|ATPase activity|cholesterol transporter activity|cholesterol transporter activity|protein heterodimerization activity|,10,0,0,10,-0.1,0.1,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000019888,MGAT4C,"MGAT4 family, member C",cellular_component|Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|biological_process|,"molecular_function|alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring hexosyl groups|metal ion binding|",10,-0.2,0.207,10,0.1,0.0335,0,0,0,0.704,0,0,-1.9,1
ENSMUSG00000041801,PHLDA3,"pleckstrin homology-like domain, family A, member 3",intracellular|cytoplasm|plasma membrane|membrane|extracellular vesicular exosome|,apoptotic process|intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of apoptotic process|negative regulation of protein kinase B signaling|,"phosphatidylinositol-4,5-bisphosphate binding|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-5-phosphate binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-3,4-bisphosphate binding|phosphatidylinositol-3,5-bisphosphate binding|",10,-0.1,0.0436,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000057716,TMEM178B,transmembrane protein 178B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000027229,4933406J08RIK,RIKEN cDNA 4933406J08 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000052759,GPR25,G protein-coupled receptor 25,cellular_component|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000041782,LAD1,ladinin,extracellular region|proteinaceous extracellular matrix|basement membrane|,None,None,10,0.1,0.406,10,0,0,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000030787,LYVE1,lymphatic vessel endothelial hyaluronan receptor 1,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|cell periphery|,glycosaminoglycan catabolic process|transport|cell adhesion|signal transduction|,transmembrane signaling receptor activity|hyaluronic acid binding|,10,0,0,10,0.1,0.27,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000016496,CD274,CD274 antigen,plasma membrane|external side of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,immune response|signal transduction|cell surface receptor signaling pathway|T cell costimulation|negative regulation of T cell proliferation|positive regulation of interleukin-10 secretion|,protein binding|,10,-0.1,0.144,10,0.1,0.156,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000078485,PLEKHN1,"pleckstrin homology domain containing, family N member 1",cellular_component|,biological_process|,protein binding|,10,0,0,10,-0.1,0.122,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000051652,LRRC3,leucine rich repeat containing 3,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.2,0.217,10,-0.1,0.0595,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000057439,KIR3DL2,"killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.204,10,0.1,0.418,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000051160,OLFR853,olfactory receptor 853,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0052,10,0,0,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000029121,CRMP1,collapsin response mediator protein 1,cytoplasm|cytoskeleton|dendrite|neuronal cell body|,pyrimidine nucleobase catabolic process|,"hydrolase activity|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds|hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides|phosphoprotein binding|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000062128,OLFR20,olfactory receptor 20,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.2,0.147,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000050248,EVC2,Ellis van Creveld syndrome 2,nucleus|nucleus|cytoplasm|cytoskeleton|plasma membrane|cilium|membrane|integral component of membrane|cell projection|,smoothened signaling pathway|,protein binding|,10,-0.8,0.239,10,0,0,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000058550,DPPA4,developmental pluripotency associated 4,nucleus|,"transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|lung-associated mesenchyme development|lung-associated mesenchyme development|",None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000056679,GPR173,G-protein coupled receptor 173,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|cellular response to gonadotropin-releasing hormone|negative regulation of neuron migration|negative regulation of neuron migration|,signal transducer activity|G-protein coupled receptor activity|gonadotropin-releasing hormone receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000075543,URAD,ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase,cellular_component|peroxisome|,purine nucleobase metabolic process|allantoin biosynthetic process|,lyase activity|carboxy-lyase activity|,10,0.3,0.713,10,0,0,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000031872,BEAN1,"brain expressed, associated with Nedd4, 1",cellular_component|membrane|integral component of membrane|,biological_process|,protein binding|,10,-1,0.458,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000031298,GPR64,G protein-coupled receptor 64,plasma membrane|membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000045629,SH3TC2,SH3 domain and tetratricopeptide repeats 2,plasma membrane|cytoplasmic vesicle|recycling endosome|,myelination in peripheral nervous system|peripheral nervous system myelin maintenance|regulation of intracellular protein transport|regulation of ERBB signaling pathway|,protein binding|,10,0.1,0.0625,10,0,0,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000040133,GPR176,G protein-coupled receptor 176,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000039620,6430573F11RIK,RIKEN cDNA 6430573F11 gene,cellular_component|,biological_process|metabolic process|methylation|,"rRNA (adenine-N6,N6-)-dimethyltransferase activity|molecular_function|protein C-terminal carboxyl O-methyltransferase activity|tRNA (guanine-N2-)-methyltransferase activity|methyltransferase activity|C-methyltransferase activity|N-methyltransferase activity|O-methyltransferase activity|S-methyltransferase activity|RNA methyltransferase activity|mRNA methyltransferase activity|tRNA methyltransferase activity|protein methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity|rRNA methyltransferase activity|rRNA (uridine-2'-O-)-methyltransferase activity|rRNA (adenine-N6-)-methyltransferase activity|DNA-methyltransferase activity|tRNA (guanine-N1-)-methyltransferase activity|rRNA (cytosine-C5-)-methyltransferase activity|selenocysteine methyltransferase activity|arginine N-methyltransferase activity|protein-arginine N-methyltransferase activity|lysine N-methyltransferase activity|protein-lysine N-methyltransferase activity|tRNA (uracil) methyltransferase activity|tRNA (guanine) methyltransferase activity|tRNA (adenine) methyltransferase activity|tRNA (cytosine) methyltransferase activity|tRNA (cytosine-5-)-methyltransferase activity|tRNA (adenine-N1-)-methyltransferase activity|rRNA (adenine) methyltransferase activity|rRNA (cytosine) methyltransferase activity|rRNA (guanine) methyltransferase activity|rRNA (uridine) methyltransferase activity|transferase activity|protein C-terminal leucine carboxyl O-methyltransferase activity|1-phenanthrol methyltransferase activity|protein-arginine N5-methyltransferase activity|methylarsonite methyltransferase activity|dimethylarsinite methyltransferase activity|4,5-dihydroxybenzo(a)pyrene methyltransferase activity|1-hydroxypyrene methyltransferase activity|1-hydroxy-6-methoxypyrene methyltransferase activity|demethylmenaquinone methyltransferase activity|cobalt-precorrin-6B C5-methyltransferase activity|cobalt-precorrin-7 C15-methyltransferase activity|cobalt-precorrin-5B C1-methyltransferase activity|cobalt-precorrin-3 C17-methyltransferase activity|dimethylamine methyltransferase activity|hydroxyneurosporene-O-methyltransferase activity|tRNA (adenine-57, 58-N(1)-) methyltransferase activity|methylamine-specific methylcobalamin:coenzyme M methyltransferase activity|trimethylamine methyltransferase activity|methanol-specific methylcobalamin:coenzyme M methyltransferase activity|monomethylamine methyltransferase activity|P-methyltransferase activity|Se-methyltransferase activity|2-phytyl-1,4-naphthoquinone methyltransferase activity|tRNA (uracil-2'-O-)-methyltransferase activity|tRNA (cytosine-2'-O-)-methyltransferase activity|phosphomethylethanolamine N-methyltransferase activity|tRNA (cytosine-3-)-methyltransferase activity|rRNA (cytosine-2'-O-)-methyltransferase activity|rRNA (cytosine-N4-)-methyltransferase activity|trihydroxyferuloyl spermidine O-methyltransferase activity|",10,-0.1,0.0349,10,0,0,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000072625,GDF2,growth differentiation factor 2,extracellular region|extracellular space|extracellular vesicular exosome|,"angiogenesis|patterning of blood vessels|patterning of blood vessels|vasculogenesis|osteoblast differentiation|negative regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|glucose metabolic process|cellular iron ion homeostasis|negative regulation of endothelial cell migration|positive regulation of gene expression|positive regulation of pathway-restricted SMAD protein phosphorylation|neuron differentiation|negative regulation of cell growth|BMP signaling pathway|positive regulation of BMP signaling pathway|positive regulation of interleukin-8 production|activin receptor signaling pathway|growth|positive regulation of endothelial cell differentiation|positive regulation of osteoblast differentiation|positive regulation of angiogenesis|positive regulation of angiogenesis|positive regulation of transcription, DNA-templated|positive regulation of transcription, DNA-templated|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|blood vessel morphogenesis|pathway-restricted SMAD protein phosphorylation|cellular response to BMP stimulus|negative regulation of DNA biosynthetic process|",cytokine activity|protein binding|growth factor activity|,10,-0.1,0.637,10,1,0.798,0,0,0,0.704,0,0,-1.1,2
ENSMUSG00000036949,SLC39A12,"solute carrier family 39 (zinc transporter), member 12",plasma membrane|membrane|integral component of membrane|perinuclear region of cytoplasm|,signal transduction|regulation of neuron projection development|metal ion transport|regulation of microtubule polymerization|transmembrane transport|zinc ion transmembrane import|divalent inorganic cation transport|,zinc ion transmembrane transporter activity|metal ion transmembrane transporter activity|,10,-0.9,0.651,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000061451,TMEM151A,transmembrane protein 151A,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000040938,SLC16A11,"solute carrier family 16 (monocarboxylic acid transporters), member 11",endoplasmic reticulum|endoplasmic reticulum membrane|membrane|integral component of membrane|,lipid metabolic process|transport|transmembrane transport|,molecular_function|symporter activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000003657,CALB2,calbindin 2,nucleus|cytoplasm|gap junction|,cytosolic calcium ion homeostasis|,calcium ion binding|metal ion binding|,10,0,0,10,-0.1,0.0633,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000029811,AOC1,"amine oxidase, copper-containing 1",extracellular region|extracellular space|plasma membrane|tight junction|extracellular vesicular exosome|,cation transport|amine metabolic process|amiloride transport|ion transmembrane transport|cellular response to copper ion starvation|response to drug|response to antibiotic|oxidation-reduction process|cellular response to copper ion|cellular response to histamine|cellular response to azide|,"receptor activity|cation channel activity|copper ion binding|calcium ion binding|primary amine oxidase activity|drug binding|heparin binding|zinc ion binding|oxidoreductase activity|protein complex binding|protein homodimerization activity|metal ion binding|quinone binding|diamine oxidase activity|histamine oxidase activity|methylputrescine oxidase activity|propane-1,3-diamine oxidase activity|",9,0,0,9,0.3,1.14,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000048003,CATSPER4,"cation channel, sperm associated 4",acrosomal vesicle|plasma membrane|cilium|membrane|integral component of membrane|CatSper complex|cell projection|sperm principal piece|,transport|ion transport|sodium ion transport|calcium ion transport|multicellular organismal development|spermatogenesis|cell differentiation|sperm motility|regulation of ion transmembrane transport|sperm capacitation|transmembrane transport|calcium ion import|calcium ion transmembrane transport|membrane depolarization during action potential|,ion channel activity|calcium activated cation channel activity|voltage-gated ion channel activity|voltage-gated calcium channel activity|voltage-gated calcium channel activity|calcium channel activity|protein binding|,10,0,0,10,-1.4,1.6,0,0,0,0.704,0,0,-3,0.5
ENSMUSG00000048706,LURAP1L,leucine rich adaptor protein 1-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.154,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000028536,2610528J11RIK,RIKEN cDNA 2610528J11 gene,membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000017943,GDAP1L1,ganglioside-induced differentiation-associated protein 1-like 1,cellular_component|,biological_process|,molecular_function|,10,0.2,0.464,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000042655,FAM159B,"family with sequence similarity 159, member B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0829,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000035407,KANK4,KN motif and ankyrin repeat domains 4,cytoplasm|,negative regulation of stress fiber assembly|,molecular_function|,10,0.1,0.202,10,-0.1,0.118,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000071510,OLFR172,olfactory receptor 172,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.5,1.64,0,0,0,0.704,0,0,-1,1.9
ENSMUSG00000013150,GFOD2,glucose-fructose oxidoreductase domain containing 2,extracellular region|proteinaceous extracellular matrix|extracellular matrix|,extracellular matrix organization|oxidation-reduction process|,molecular_function|N-ethylmaleimide reductase activity|oxidoreductase activity|reduced coenzyme F420 dehydrogenase activity|sulfur oxygenase reductase activity|malolactic enzyme activity|NADPH:sulfur oxidoreductase activity|epoxyqueuosine reductase activity|,10,0,0,10,0.2,0.333,0,0,0,0.704,0,0,-2,1
ENSMUSG00000051452,GM11437,predicted gene 11437,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0405,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000032346,OOEP,oocyte expressed protein,cytoplasm|cell cortex|protein complex|apical part of cell|,in utero embryonic development|protein phosphorylation|embryo implantation|fertilization|embryonic pattern specification|establishment or maintenance of apical/basal cell polarity|cellular protein complex assembly|,RNA binding|protein binding|,10,0,0,10,0.6,1.43,0,0,0,0.704,0,0,-0.8,2
ENSMUSG00000022014,EPSTI1,epithelial stromal interaction 1 (breast),cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.193,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000091129,IQCF6,IQ motif containing F6,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0743,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000038085,CNBD2,cyclic nucleotide binding domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.554,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000045667,SMTNL2,smoothelin-like 2,cellular_component|,biological_process|,molecular_function|,10,-0.3,0.411,10,0,0,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000046210,OLFR735,olfactory receptor 735,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000074594,WFDC9,WAP four-disulfide core domain 9,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000091873,OLFR732,olfactory receptor 732,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.322,10,0.1,0.115,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000093550,HIGD1C,"HIG1 domain family, member 1C",cellular_component|,biological_process|,molecular_function|,4,0.4,0.64,4,0,0,0,0,0,0.704,0,0,-1.4,2
ENSMUSG00000087385,AA415398,expressed sequence AA415398,None,None,None,10,0,0,10,-0.2,0.492,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000026390,MARCO,macrophage receptor with collagenous structure,collagen trimer|membrane|integral component of membrane|,immune system process|endocytosis|apoptotic cell clearance|innate immune response|,scavenger receptor activity|,9,0,0,9,0.4,1.38,0,0,0,0.704,0,0,-1.8,1.4
ENSMUSG00000036169,SOSTDC1,sclerostin domain containing 1,extracellular region|extracellular space|,pattern specification process|negative regulation of cell fate commitment|Wnt signaling pathway|negative regulation of BMP signaling pathway|negative regulation of BMP signaling pathway|hair follicle morphogenesis|odontogenesis of dentin-containing tooth|odontogenesis of dentin-containing tooth|mammary gland bud morphogenesis|negative regulation of canonical Wnt signaling pathway|,protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000045165,AI467606,expressed sequence AI467606,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000028351,BRINP1,bone morphogenic protein/retinoic acid inducible neural specific 1,cytoplasm|,cell cycle|cell cycle arrest|cell death|positive regulation of neuron differentiation|negative regulation of cell cycle|negative regulation of mitotic cell cycle|cellular response to retinoic acid|,molecular_function|,10,-0.2,0.345,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000029831,NPVF,neuropeptide VF precursor,extracellular region|,neuropeptide signaling pathway|sensory perception of pain|negative regulation of gonadotropin secretion|,receptor binding|,10,-0.2,0.499,10,0.2,0.289,0,0,0,0.704,0,0,-1.9,1
ENSMUSG00000071073,LRRC73,leucine rich repeat containing 73,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000024806,MLANA,melan-A,endoplasmic reticulum membrane|Golgi apparatus|trans-Golgi network|melanosome|,None,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000078963,HSBP1L1,heat shock factor binding protein 1-like 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000048070,PIRT,phosphoinositide-interacting regulator of transient receptor potential channels,membrane|integral component of membrane|,None,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000044787,SPATA32,spermatogenesis associated 32,perinuclear region of cytoplasm|,spermatogenesis|biological_process|,actin binding|,10,0.2,0.273,10,0,0,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000053063,CLEC12A,"C-type lectin domain family 12, member a",plasma membrane|cell surface|membrane|integral component of membrane|,regulation of immune response|,protein phosphatase binding|carbohydrate binding|,10,-0.1,0.27,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000026226,SPATA3,spermatogenesis associated 3,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.348,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000056174,COL8A2,"collagen, type VIII, alpha 2",extracellular region|proteinaceous extracellular matrix|collagen trimer|basement membrane|extracellular matrix|,angiogenesis|cell adhesion|camera-type eye morphogenesis|epithelial cell proliferation|,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000043357,OLFR187,olfactory receptor 187,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.2,0.623,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000029680,HYAL4,hyaluronoglucosaminidase 4,cell surface|membrane|integral component of membrane|,carbohydrate metabolic process|metabolic process|chondroitin sulfate catabolic process|,"catalytic activity|hyalurononglucosaminidase activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0,0,10,-0.1,0.142,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000036027,1810046K07RIK,RIKEN cDNA 1810046K07 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000024647,CBLN2,cerebellin 2 precursor protein,extracellular region|extracellular space|,positive regulation of synapse assembly|,protein binding|,10,-0.1,0.123,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000094595,FSBP,fibrinogen silencer binding protein,nucleus|,biological_process|,molecular_function|,10,0,0,10,0.1,0.219,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000050700,EMILIN3,elastin microfibril interfacer 3,extracellular region|proteinaceous extracellular matrix|cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000027560,DOK5,docking protein 5,intracellular|,MAPK cascade|transmembrane receptor protein tyrosine kinase signaling pathway|nervous system development|intracellular signal transduction|,receptor signaling protein activity|insulin receptor binding|,10,0.1,0.12,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000034842,ART3,ADP-ribosyltransferase 3,cellular_component|plasma membrane|membrane|anchored component of membrane|,protein ADP-ribosylation|biological_process|,"molecular_function|NAD(P)+-protein-arginine ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.1,0.0206,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000028174,RPE65,retinal pigment epithelium 65,cytoplasm|endoplasmic reticulum|plasma membrane|membrane|intracellular membrane-bounded organelle|cell body|,retina homeostasis|regulation of rhodopsin gene expression|visual perception|insulin receptor signaling pathway|retinol metabolic process|retinal metabolic process|retinal metabolic process|response to stimulus|detection of light stimulus involved in visual perception|retina development in camera-type eye|retina morphogenesis in camera-type eye|cellular response to electrical stimulus|,"retinal isomerase activity|hydrolase activity|isomerase activity|metal ion binding|all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity|all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity|",10,-0.1,0.318,10,0.1,0.00625,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000043354,OLFR577,olfactory receptor 577,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000091938,GM2564,predicted gene 2564,cellular_component|extracellular space|,biological_process|,molecular_function|cytokine activity|,10,-0.1,0.219,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000044055,OTOS,otospiralin,extracellular region|,sensory perception of sound|sensory perception of sound|,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000044461,SHISA2,shisa family member 2,endoplasmic reticulum|membrane|integral component of membrane|,multicellular organismal development|,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000041737,TMEM45B,transmembrane protein 45b,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.281,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000047733,BC048609,cDNA sequence BC048609,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000004988,FXYD4,FXYD domain-containing ion transport regulator 4,membrane|integral component of membrane|,transport|ion transport|potassium ion transmembrane transport|,ion channel activity|potassium channel activity|ATPase binding|,6,-0.1,0.0391,6,0,0,0,0,0,0.704,0,0,-1.8,1.5
ENSMUSG00000074006,OMP,olfactory marker protein,nucleus|cytoplasm|cytosol|cytosol|axon|neuronal cell body|,signal transduction|sensory perception of smell|neurogenesis|response to stimulus|,signal transducer activity|peptide binding|,10,0,0,10,0.1,0.085,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000056888,GLIPR1,GLI pathogenesis-related 1 (glioma),extracellular region|membrane|membrane|integral component of membrane|,None,None,10,0.1,0.0953,10,-0.3,0.215,0,0,0,0.704,0,0,-1.8,1
ENSMUSG00000061344,OLFR320,olfactory receptor 320,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0899,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000050224,KRTAP13,keratin associated protein 13,intermediate filament|,None,None,10,0.1,0.164,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000051056,GJA10,"gap junction protein, alpha 10",plasma membrane|gap junction|connexon complex|membrane|integral component of membrane|cell junction|,cell communication|gamete generation|synapse assembly|response to light stimulus|detection of light stimulus involved in visual perception|transmembrane transport|,gap junction channel activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000045930,CLEC14A,"C-type lectin domain family 14, member a",membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,carbohydrate binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000073967,OLFR557,olfactory receptor 557,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000050623,TEX40,testis expressed 40,cytoplasm|,spermatogenesis|biological_process|cell differentiation|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000024340,BTNL2,butyrophilin-like 2,membrane|integral component of membrane|,positive regulation of T cell proliferation|negative regulation of T cell receptor signaling pathway|positive regulation of interleukin-2 secretion|,receptor binding|,10,0.1,0.305,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000023886,SMOC2,SPARC related modular calcium binding 2,extracellular region|proteinaceous extracellular matrix|basement membrane|interstitial matrix|extracellular matrix|,signal transduction|positive regulation of cell-substrate adhesion|extracellular matrix organization|,calcium ion binding|glycosaminoglycan binding|heparin binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000027718,IL21,interleukin 21,extracellular region|extracellular space|,B cell apoptotic process|positive regulation of natural killer cell cytokine production|immune response|positive regulation of cell proliferation|positive regulation of B cell proliferation|positive regulation of interleukin-10 production|positive regulation of interleukin-17 production|positive regulation of natural killer cell differentiation|positive regulation of T cell proliferation|positive regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|positive regulation of interferon-gamma biosynthetic process|positive regulation of B cell differentiation|positive regulation of natural killer cell mediated cytotoxicity|cell maturation|,cytokine activity|cytokine receptor binding|interleukin-2 receptor binding|,10,0,0,10,0.2,0.612,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000069671,NKAIN2,Na+/K+ transporting ATPase interacting 2,plasma membrane|membrane|integral component of membrane|,None,None,10,0,0,10,-0.1,0.244,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000045776,LRTM1,leucine-rich repeats and transmembrane domains 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000090439,GM17455,"predicted gene, 17455",None,None,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000062987,GM10081,predicted gene 10081,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|biological_process|response to stimulus|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.1,0.353,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000050121,OPALIN,oligodendrocytic myelin paranodal and inner loop protein,Golgi apparatus|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000042371,SLC5A10,"solute carrier family 5 (sodium/glucose cotransporter), member 10",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|transmembrane transport|,transporter activity|,10,0.1,0.151,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000044811,AF251705,cDNA sequence AF251705,plasma membrane|plasma membrane|membrane|integral component of membrane|,immune system process|positive regulation of cytokine secretion|,protein binding|,10,-0.9,1.1,10,0.1,0.0762,0,0,0,0.704,0,0,-2,0.7
ENSMUSG00000054435,GIMAP4,"GTPase, IMAP family member 4",cytoplasm|cytosol|,None,nucleotide binding|GTP binding|,10,0.1,0.0883,10,-0.5,0.698,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000060512,0610040J01RIK,RIKEN cDNA 0610040J01 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.522,10,0,0,0,0,0,0.704,0,0,-0.8,2
ENSMUSG00000049018,OLFR368,olfactory receptor 368,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.5,0.519,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000040536,NECAB1,N-terminal EF-hand calcium binding protein 1,nucleus|cytoplasm|,biological_process|,calcium ion binding|metal ion binding|,10,0.2,0.376,9,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000051951,XKR4,X Kell blood group precursor related family member 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000035448,CCR3,chemokine (C-C motif) receptor 3,extracellular space|endosome|plasma membrane|membrane|integral component of membrane|,positive regulation of endothelial cell proliferation|mast cell chemotaxis|chemotaxis|inflammatory response|signal transduction|G-protein coupled receptor signaling pathway|angioblast cell migration|positive regulation of angiogenesis|positive regulation of angiogenesis|eosinophil chemotaxis|chemokine-mediated signaling pathway|ERK1 and ERK2 cascade|,signal transducer activity|G-protein coupled receptor activity|chemokine receptor activity|protein binding|C-C chemokine receptor activity|,10,0,0,10,-0.1,0.0212,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000037892,PCDH18,protocadherin 18,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,cell adhesion|homophilic cell adhesion|calcium-dependent cell-cell adhesion|,calcium ion binding|protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000052276,OSTN,osteocrin,extracellular region|extracellular space|,ossification|endochondral bone growth|cell surface receptor signaling pathway|multicellular organismal development|cell differentiation|regulation of bone mineralization|positive regulation of cGMP biosynthetic process|negative regulation of osteoblast differentiation|negative regulation of glucose import|,receptor binding|hormone activity|,10,0.7,0.0868,10,0,0,0,0,0,0.704,0,0,-1.1,2
ENSMUSG00000027894,SLC6A17,"solute carrier family 6 (neurotransmitter transporter), member 17",cellular_component|integral component of plasma membrane|synaptic vesicle|membrane|integral component of membrane|cell junction|cytoplasmic vesicle|synapse|,transport|neurotransmitter transport|neutral amino acid transport|glycine transport|leucine transport|proline transport|alanine transport|,neurotransmitter:sodium symporter activity|symporter activity|,10,0,0,10,0.4,0.506,0,0,0,0.704,0,0,-0.9,1.9
ENSMUSG00000046108,IL17C,interleukin 17C,extracellular region|extracellular space|,inflammatory response|neutrophil differentiation|positive regulation of cytokine production involved in inflammatory response|,cytokine activity|,9,-0.1,0.416,9,0.1,0.253,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000037843,VSTM2L,V-set and transmembrane domain containing 2-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000038064,CLDN22,claudin 22,cellular_component|plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,biological_process|,molecular_function|structural molecule activity|,10,0.1,0.216,10,0,0,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000037924,OLFR16,olfactory receptor 16,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.108,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000075302,ERICH2,glutamate rich 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000062593,LILRB4,"leukocyte immunoglobulin-like receptor, subfamily B, member 4",plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,immune system process|,None,10,-0.1,0.222,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000072494,PPP1R3E,"protein phosphatase 1, regulatory (inhibitor) subunit 3E",glycogen granule|,carbohydrate metabolic process|glycogen metabolic process|regulation of glycogen biosynthetic process|regulation of glycogen catabolic process|dephosphorylation|,phosphoprotein phosphatase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000044724,GPR152,G protein-coupled receptor 152,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,-0.2,0.332,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000051777,IQCJ,IQ motif containing J,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000067604,NMS,neuromedin S,extracellular region|,neuropeptide signaling pathway|locomotor rhythm|,G-protein coupled receptor binding|,10,-0.7,0.11,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000016356,COL20A1,"collagen, type XX, alpha 1",cellular_component|extracellular region|collagen trimer|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000048329,MFSD6L,major facilitator superfamily domain containing 6-like,cellular_component|membrane|integral component of membrane|,biological_process|transmembrane transport|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000097487,PTGES3L,prostaglandin E synthase 3 (cytosolic)-like,cellular_component|,biological_process|,molecular_function|,10,0.1,0.0637,10,-0.3,0.559,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000028716,PDZK1IP1,PDZK1 interacting protein 1,membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,molecular_function|,10,-0.1,0.319,10,0.2,0.102,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000087279,4930544D05RIK,RIKEN cDNA 4930544D05 gene,cellular_component|,biological_process|,molecular_function|,10,-1.4,2.05,10,-0.1,0.033,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000036958,CST11,cystatin 11,cellular_component|extracellular region|,biological_process|negative regulation of peptidase activity|,molecular_function|cysteine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,-0.1,0.343,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000041708,MPPED1,metallophosphoesterase domain containing 1,cellular_component|,biological_process|,molecular_function|nuclease activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000038115,ANO2,anoctamin 2,nucleus|plasma membrane|plasma membrane|membrane|integral component of membrane|nonmotile primary cilium|chloride channel complex|,transport|ion transport|chloride transport|chloride transport|chloride transmembrane transport|chloride transmembrane transport|,intracellular calcium activated chloride channel activity|intracellular calcium activated chloride channel activity|intracellular calcium activated chloride channel activity|chloride channel activity|protein binding|protein homodimerization activity|protein heterodimerization activity|,10,0,0,10,-1.1,2.35,0,0,0,0.704,0,0,-2,0.6
ENSMUSG00000090121,ABHD12B,abhydrolase domain containing 12B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.202,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000000791,IL12RB1,"interleukin 12 receptor, beta 1",external side of plasma membrane|membrane|integral component of membrane|interleukin-12 receptor complex|interleukin-23 receptor complex|,positive regulation of defense response to virus by host|positive regulation of T-helper 1 type immune response|peptidyl-tyrosine phosphorylation|positive regulation of interferon-gamma production|interleukin-12-mediated signaling pathway|interleukin-23-mediated signaling pathway|positive regulation of activated T cell proliferation|cellular response to interferon-gamma|,interleukin-12 receptor binding|protein binding|interleukin-12 receptor activity|cytokine binding|interleukin-23 binding|interleukin-23 receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000056858,OLFR1502,olfactory receptor 1502,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000047557,LXN,latexin,cytoplasm|extracellular vesicular exosome|,inflammatory response|negative regulation of peptidase activity|negative regulation of endopeptidase activity|detection of temperature stimulus involved in sensory perception of pain|,enzyme inhibitor activity|metalloendopeptidase inhibitor activity|heparin binding|peptidase inhibitor activity|,10,-0.6,1.43,10,-0.1,0.0629,0,0,0,0.704,0,0,-2,0.5
ENSMUSG00000067615,KRT81,keratin 81,extracellular space|intermediate filament|keratin filament|,biological_process|,molecular_function|structural molecule activity|,10,-0.9,0.256,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000038094,ATP13A4,ATPase type 13A4,endoplasmic reticulum membrane|membrane|integral component of membrane|,ATP catabolic process|cation transport|cellular calcium ion homeostasis|calcium ion transmembrane transport|,nucleotide binding|calcium-transporting ATPase activity|ATP binding|hydrolase activity|ATPase activity|cation-transporting ATPase activity|metal ion binding|,10,0.7,0.709,10,0,0,0,0,0,0.704,0,0,-0.9,1.9
ENSMUSG00000036040,ADAMTSL2,ADAMTS-like 2,extracellular region|proteinaceous extracellular matrix|extracellular matrix|,negative regulation of transforming growth factor beta receptor signaling pathway|,molecular_function|metalloendopeptidase activity|peptidase activity|metallopeptidase activity|zinc ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.1,2
ENSMUSG00000043687,1190005I06RIK,RIKEN cDNA 1190005I06 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0527,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000026841,FIBCD1,fibrinogen C domain containing 1,membrane|integral component of membrane|,None,chitin binding|metal ion binding|,10,-0.1,0.136,10,0.2,0.324,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000095270,IFNA9,interferon alpha 9,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000093920,OLFR463,olfactory receptor 463,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000091490,TRIML2,tripartite motif family-like 2,cellular_component|,response to organic substance|response to retinoic acid|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000060402,CHST8,carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8,Golgi apparatus|membrane|integral component of membrane|,carbohydrate metabolic process|sulfur compound metabolic process|carbohydrate biosynthetic process|peptide hormone processing|proteoglycan biosynthetic process|proteoglycan biosynthetic process|,"N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0.1,0.214,10,-0.2,0.279,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000026009,ICOS,inducible T cell co-stimulator,integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,T cell tolerance induction|single organismal cell-cell adhesion|T cell costimulation|,protein binding|,10,-1.2,3.18,10,0,0,0,0,0,0.704,0,0,-2,0.7
ENSMUSG00000043880,OLFR323,olfactory receptor 323,plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.1,1.8
ENSMUSG00000078746,GM20938,"predicted gene, 20938",None,None,None,10,0,0,10,-0.1,0.0769,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000046006,GAPT,"Grb2-binding adaptor, transmembrane",plasma membrane|membrane|integral component of membrane|,B cell homeostasis|B cell proliferation involved in immune response|immunoglobulin production involved in immunoglobulin mediated immune response|B cell activation|,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000020401,FAM71B,"family with sequence similarity 71, member B",nucleus|,biological_process|,molecular_function|,10,-0.2,0.371,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000046450,OLFR71,olfactory receptor 71,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|sensory perception of smell|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.5
ENSMUSG00000071005,CCL19,chemokine (C-C motif) ligand 19,intracellular|cell|external side of plasma membrane|,establishment of T cell polarity|dendritic cell chemotaxis|myeloid dendritic cell chemotaxis|response to prostaglandin E|positive regulation of NF-kappaB import into nucleus|positive regulation of I-kappaB kinase/NF-kappaB signaling|positive regulation of phosphatidylinositol 3-kinase activity|positive regulation of protein kinase activity|positive regulation of JNK cascade|release of sequestered calcium ion into cytosol|positive regulation of protein kinase B signaling|positive regulation of ERK1 and ERK2 cascade|response to nitric oxide|positive regulation of neutrophil chemotaxis|negative regulation of leukocyte apoptotic process|positive regulation of cell motility|,chemokine activity|CCR10 chemokine receptor binding|chemokine receptor binding|CCR chemokine receptor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000046157,TMEM229B,transmembrane protein 229B,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.4,1.56,0,0,0,0.704,0,0,-0.7,2
ENSMUSG00000073207,CCDC160,coiled-coil domain containing 160,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.1,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000039508,FAM26D,"family with sequence similarity 26, member D",cellular_component|membrane|integral component of membrane|,transport|ion transport|biological_process|,molecular_function|,10,-0.3,0.218,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000075112,OLFR1211,olfactory receptor 1211,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0142,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000027670,OCSTAMP,osteoclast stimulatory transmembrane protein,cellular_component|membrane|integral component of membrane|,cell differentiation|positive regulation of macrophage fusion|positive regulation of osteoclast differentiation|cellular response to tumor necrosis factor|cellular response to estrogen stimulus|multinuclear osteoclast differentiation|positive regulation of osteoclast proliferation|,molecular_function|,10,-0.1,0.000465,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000070983,OLFR270,olfactory receptor 270,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.3,1.04,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000031837,NECAB2,N-terminal EF-hand calcium binding protein 2,cytoplasm|,None,calcium ion binding|metal ion binding|,10,0,0,10,-0.1,0.264,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000044229,NXPE4,"neurexophilin and PC-esterase domain family, member 4",extracellular region|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0.1,0.48,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000025058,5430427O19RIK,RIKEN cDNA 5430427O19 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.144,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000055838,OLFR357,olfactory receptor 357,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.119,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000020467,EFEMP1,epidermal growth factor-containing fibulin-like extracellular matrix protein 1,extracellular region|proteinaceous extracellular matrix|extracellular space|extracellular matrix|extracellular vesicular exosome|,"regulation of transcription, DNA-templated|epidermal growth factor receptor signaling pathway|peptidyl-tyrosine phosphorylation|negative regulation of chondrocyte differentiation|",epidermal growth factor-activated receptor activity|epidermal growth factor receptor binding|calcium ion binding|growth factor activity|,10,0.1,0.313,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000069806,CACNG7,"calcium channel, voltage-dependent, gamma subunit 7",membrane|integral component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,transport|ion transport|calcium ion transport|regulation of ion transmembrane transport|calcium ion transmembrane transport|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,voltage-gated ion channel activity|calcium channel activity|,10,0,0,10,0.8,0.612,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000095970,GM19402,"predicted gene, 19402",intermediate filament|,None,None,10,-0.1,0.0227,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000048830,2310057N15RIK,RIKEN cDNA 2310057N15 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.382,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000022947,CBR3,carbonyl reductase 3,extracellular space|nucleus|cytoplasm|cytosol|,metabolic process|phylloquinone catabolic process|cognition|oxidation-reduction process|,3-keto sterol reductase activity|carbonyl reductase (NADPH) activity|oxidoreductase activity|NADPH binding|,10,0,0,10,0.1,0.00783,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000052549,ARL13A,ADP-ribosylation factor-like 13A,cellular_component|intracellular|,small GTPase mediated signal transduction|biological_process|,nucleotide binding|GTP binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000028699,TSPAN1,tetraspanin 1,cytoplasm|lysosome|plasma membrane|membrane|membrane|integral component of membrane|vesicle|perinuclear region of cytoplasm|extracellular vesicular exosome|,cell proliferation|cell migration|positive regulation of endocytosis|protein stabilization|thiamine transmembrane transport|,thiamine uptake transmembrane transporter activity|,10,-0.1,0.000998,10,0.1,0.233,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000009214,TMEM8C,transmembrane protein 8C,plasma membrane|membrane|integral component of membrane|,muscle organ development|myoblast fusion|plasma membrane fusion|,molecular_function|,10,0,0,10,-0.1,0.00496,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000087247,FAM150A,"family with sequence similarity 150, member A",cellular_component|,biological_process|,molecular_function|,10,-0.2,0.87,10,0.1,0.0429,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000049625,TIFAB,"TRAF-interacting protein with forkhead-associated domain, family member B",cellular_component|,biological_process|,molecular_function|,10,-0.1,0.162,10,0.1,0.237,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000095896,IFNA14,interferon alpha 14,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|type I interferon receptor binding|,10,0.2,0.279,10,-0.1,0.0558,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000045589,FRRS1L,ferric-chelate reductase 1 like,cellular_component|plasma membrane|membrane|integral component of membrane|cell junction|synapse|,biological_process|,molecular_function|,10,-0.1,0.135,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000022512,CLDN1,claudin 1,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|tight junction|tight junction|membrane|integral component of membrane|apical plasma membrane|lateral plasma membrane|lateral plasma membrane|cell junction|,calcium-independent cell-cell adhesion|cell-cell junction organization|establishment of skin barrier|establishment of skin barrier|,structural molecule activity|protein binding|identical protein binding|,10,0.1,0.059,10,-0.1,0.277,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000024731,MS4A10,"membrane-spanning 4-domains, subfamily A, member 10",membrane|integral component of membrane|,None,protein binding|,9,0,0,9,0,0,0,0,0,0.704,0,0,-1.5,1.7
ENSMUSG00000059169,KRT40,keratin 40,intermediate filament|,biological_process|,structural molecule activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000026220,SLC16A14,"solute carrier family 16 (monocarboxylic acid transporters), member 14",cellular_component|plasma membrane|membrane|integral component of membrane|,transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000090291,LRRC10B,leucine rich repeat containing 10B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000043388,TMEM130,transmembrane protein 130,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000053070,9230110C19RIK,RIKEN cDNA 9230110C19 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000045672,COL27A1,"collagen, type XXVII, alpha 1",extracellular region|proteinaceous extracellular matrix|collagen trimer|fibrillar collagen trimer|,growth plate cartilage chondrocyte development|extracellular matrix organization|,extracellular matrix structural constituent|metal ion binding|,10,-0.2,0.786,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000038233,FAM198A,"family with sequence similarity 198, member A",cellular_component|extracellular region|,biological_process|,molecular_function|,10,0.1,0.101,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000037660,GDF7,growth differentiation factor 7,extracellular region|extracellular space|,"axon guidance|positive regulation of gene expression|positive regulation of pathway-restricted SMAD protein phosphorylation|roof plate formation|spinal cord association neuron differentiation|neural tube development|gland morphogenesis|BMP signaling pathway|BMP signaling pathway|BMP signaling pathway|epithelial cell differentiation|midbrain development|activin receptor signaling pathway|growth|cell fate commitment|positive regulation of neuron differentiation|positive regulation of transcription, DNA-templated|reproductive structure development|branching morphogenesis of an epithelial tube|forebrain morphogenesis|pathway-restricted SMAD protein phosphorylation|morphogenesis of an epithelial fold|positive regulation of tendon cell differentiation|",cytokine activity|protein binding|growth factor activity|protein homodimerization activity|,10,-0.1,0.0473,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000007682,DIO2,"deiodinase, iodothyronine, type II",cell|membrane|integral component of membrane|,thyroid hormone generation|response to cold|thyroid hormone metabolic process|thyroid hormone catabolic process|hormone biosynthetic process|oxidation-reduction process|thyroid-stimulating hormone secretion|,thyroxine 5'-deiodinase activity|thyroxine 5'-deiodinase activity|thyroxine 5'-deiodinase activity|oxidoreductase activity|ubiquitin protein ligase binding|,10,-0.2,0.469,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000029282,AMTN,amelotin,extracellular region|proteinaceous extracellular matrix|proteinaceous extracellular matrix|proteinaceous extracellular matrix|basal lamina|basal lamina|cell-cell junction|cell-cell junction|,cell adhesion|biological_process|biomineral tissue development|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000036574,1700019O17RIK,RIKEN cDNA 1700019O17 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.106,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000057674,GM11938,predicted gene 11938,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.622,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000046916,MYCT1,myc target 1,cellular_component|nucleus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.5,0.57,0,0,0,0.704,0,0,-1,2
ENSMUSG00000032625,THSD7A,"thrombospondin, type I, domain containing 7A",extracellular region|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,angiogenesis|biological_process|cell differentiation|,molecular_function|,10,0.2,0.637,10,-0.9,0.999,0,0,0,0.704,0,0,-2,1.2
ENSMUSG00000026348,ACMSD,amino carboxymuconate semialdehyde decarboxylase,cytosol|extracellular vesicular exosome|,metabolic process|quinolinate metabolic process|,aminocarboxymuconate-semialdehyde decarboxylase activity|catalytic activity|lyase activity|carboxy-lyase activity|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000022523,FGF12,fibroblast growth factor 12,nucleus|,regulation of membrane depolarization|JNK cascade|synaptic transmission|adult locomotory behavior|positive regulation of sodium ion transport|neuromuscular process|regulation of sodium ion transmembrane transport|regulation of sodium ion transmembrane transporter activity|negative regulation of cation channel activity|,receptor binding|protein binding|growth factor activity|heparin binding|sodium channel regulator activity|ion channel binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000035506,SLC12A8,"solute carrier family 12 (potassium/chloride transporters), member 8",membrane|integral component of membrane|,transport|ion transport|potassium ion transport|transmembrane transport|,symporter activity|,10,0.1,0.0625,10,-0.2,0.187,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000034898,FILIP1,filamin A interacting protein 1,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.164,10,0.2,0.511,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000028184,LPHN2,latrophilin 2,plasma membrane|membrane|integral component of membrane|neuron projection|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|biological_process|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|PDZ domain binding|,10,0.2,0.107,10,0,0,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000078353,IFNAB,interferon alpha B,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|type I interferon receptor binding|,9,-0.1,0.144,9,0,0,0,0,0,0.704,0,0,-2,1.1
ENSMUSG00000029321,SLC10A6,"solute carrier family 10 (sodium/bile acid cotransporter family), member 6",membrane|integral component of membrane|,transport|ion transport|sodium ion transport|ion transmembrane transport|sodium-dependent organic anion transport|,bile acid:sodium symporter activity|symporter activity|sodium-dependent organic anion transmembrane transporter activity|,10,0,0,10,0.1,0.103,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000046245,PILRA,paired immunoglobin-like type 2 receptor alpha,membrane|integral component of membrane|extracellular vesicular exosome|,signal transduction|,protein binding|,10,0,0,10,-0.1,0.0772,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000035551,IGFBPL1,insulin-like growth factor binding protein-like 1,extracellular region|,regulation of cell growth|,insulin-like growth factor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000075023,ACCSL,1-aminocyclopropane-1-carboxylate synthase (non-functional)-like,cellular_component|,biological_process|biosynthetic process|,catalytic activity|pyridoxal phosphate binding|,10,-0.1,0.631,10,0.1,0.088,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000039720,GOT1L1,glutamic-oxaloacetic transaminase 1-like 1,cellular_component|cytoplasm|,cellular amino acid metabolic process|biological_process|biosynthetic process|,catalytic activity|transaminase activity|methionine-oxo-acid transaminase activity|transferase activity|6-aminohexanoate transaminase activity|pyridoxal phosphate binding|N2-acetyl-L-lysine aminotransferase activity|acetyldiaminopimelate aminotransferase activity|branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity|D-lysine transaminase activity|aspartate-2-keto-4-methylthiobutyrate transaminase activity|,10,-0.2,0.198,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000031682,1700011L22RIK,RIKEN cDNA 1700011L22 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000091080,PRR23A,proline rich 23A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.072,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000031937,VSTM5,V-set and transmembrane domain containing 5,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0,0,9,0.1,0.0972,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000078577,TMCO2,transmembrane and coiled-coil domains 2,nucleus|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.000285,10,-0.1,0.282,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000037424,TAAR9,trace amine-associated receptor 9,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,trace-amine receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|,10,0.1,0.405,10,-1.3,0.896,0,0,0,0.704,0,0,-2,0.7
ENSMUSG00000047443,FAM132B,"family with sequence similarity 132, member B",extracellular region|extracellular space|,regulation of fatty acid metabolic process|positive regulation of fatty acid transport|,protein homodimerization activity|,10,0,0,10,0.5,0.37,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000075208,OLFR1019,olfactory receptor 1019,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.49,10,0.1,0.0468,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000027431,SCP2D1,SCP2 sterol-binding domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000043164,TMEM212,transmembrane protein 212,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.187,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000043441,GPR149,G protein-coupled receptor 149,cellular_component|plasma membrane|membrane|integral component of membrane|,preantral ovarian follicle growth|antral ovarian follicle growth|signal transduction|G-protein coupled receptor signaling pathway|estrous cycle phase|negative regulation of ovulation|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,-0.1,0.165,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000092113,TAAR8B,trace amine-associated receptor 8B,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,trace-amine receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|,10,-0.3,0.676,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000093996,GM21598,"predicted gene, 21598",None,None,None,10,0,0,10,-0.1,0.0769,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000046743,FAT4,FAT tumor suppressor homolog 4 (Drosophila),intracellular|plasma membrane|membrane|integral component of membrane|apical part of cell|extracellular vesicular exosome|,branching involved in ureteric bud morphogenesis|establishment of planar polarity|kidney development|heart morphogenesis|plasma membrane organization|cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|cerebral cortex development|neurogenesis|hippo signaling|ossification involved in bone maturation|digestive tract development|inner ear receptor stereocilium organization|regulation of metanephric nephron tubule epithelial cell differentiation|,calcium ion binding|protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000030428,TTYH1,tweety homolog 1 (Drosophila),plasma membrane|membrane|integral component of membrane|axon|smooth endoplasmic reticulum membrane|filopodium membrane|filopodium tip|chloride channel complex|,transport|ion transport|chloride transport|mitotic nuclear division|cell adhesion|single organismal cell-cell adhesion|cell-substrate adhesion|regulation of anion transport|filopodium assembly|chloride transmembrane transport|,chloride channel activity|calcium ion binding|volume-sensitive chloride channel activity|,9,0.7,1.2,9,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000071679,ZCCHC16,"zinc finger, CCHC domain containing 16",cellular_component|,biological_process|,molecular_function|nucleic acid binding|zinc ion binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000046806,3110062M04RIK,RIKEN cDNA 3110062M04 gene,cellular_component|cytoplasm|,biological_process|,molecular_function|,10,0.3,0.382,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000039865,SLC44A3,"solute carrier family 44, member 3",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.4,1.26,0,0,0,0.704,0,0,-1,1.9
ENSMUSG00000069998,OLFR372,olfactory receptor 372,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.11,10,0,0,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000038663,FSD2,fibronectin type III and SPRY domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.431,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000059379,OLFR1014,olfactory receptor 1014,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.9,1.2
ENSMUSG00000050015,OLFR350,olfactory receptor 350,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.442,10,0,0,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000045364,IFNE,interferon epsilon,extracellular region|extracellular space|,adaptive immune response|T cell activation involved in immune response|natural killer cell activation involved in immune response|defense response|humoral immune response|cytokine-mediated signaling pathway|B cell differentiation|positive regulation of peptidyl-serine phosphorylation of STAT protein|B cell proliferation|defense response to bacterium|response to exogenous dsRNA|innate immune response|regulation of MHC class I biosynthetic process|defense response to virus|,cytokine activity|cytokine receptor binding|type I interferon receptor binding|,10,0,0,10,-1.1,1.66,0,0,0,0.704,0,0,-2,1.2
ENSMUSG00000037703,LZTS3,"leucine zipper, putative tumor suppressor family member 3",cytoplasm|cytoskeleton|plasma membrane|postsynaptic density|membrane|cell junction|dendritic spine|synapse|postsynaptic membrane|,protein homooligomerization|,PDZ domain binding|protein self-association|,10,0,0,10,-0.2,0.47,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000091735,GPR62,G protein-coupled receptor 62,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000018543,1700001P01RIK,RIKEN cDNA 1700001P01 gene,cellular_component|,biological_process|,molecular_function|,10,1.5,0.0948,10,0,0,0,0,0,0.704,0,0,-1.1,3
ENSMUSG00000023279,BMP15,bone morphogenetic protein 15,extracellular region|extracellular space|cytoplasm|,"ovarian follicle development|positive regulation of transcription, DNA-templated|granulosa cell development|",cytokine activity|growth factor activity|,10,-0.4,0.964,10,0,0,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000047420,FAM180A,"family with sequence similarity 180, member A",cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.501,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000071858,GM94,predicted gene 94,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0.1,0.249,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000064147,RAB44,"RAB44, member RAS oncogene family",cellular_component|plasma membrane|membrane|,small GTPase mediated signal transduction|protein transport|,nucleotide binding|GTP binding|,10,0.1,0.00829,10,-0.1,0.0119,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000025666,TMEM47,transmembrane protein 47,plasma membrane|cell-cell junction|membrane|integral component of membrane|cell junction|,None,None,10,0.1,0.0494,10,0,0,0,0,0,0.704,0,0,-1.1,1.8
ENSMUSG00000070609,GM13177,predicted gene 13177,cellular_component|,biological_process|,molecular_function|,10,-1.3,2.93,10,0,0,0,0,0,0.704,0,0,-2,0.4
ENSMUSG00000050276,MRGPRG,"MAS-related GPR, member G",cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0.1,0.107,10,-0.1,0.0821,0,0,0,0.704,0,0,-0.8,2
ENSMUSG00000053338,TARM1,"T cell-interacting, activating receptor on myeloid cells 1",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.112,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000025324,ATP10A,"ATPase, class V, type 10A",endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|,transport|cation transport|lipid transport|phospholipid transport|,nucleotide binding|magnesium ion binding|phospholipid-translocating ATPase activity|ATP binding|hydrolase activity|cation-transporting ATPase activity|metal ion binding|,10,0.3,0.71,10,0,0,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000041014,NRG3,neuregulin 3,extracellular region|intracellular|plasma membrane|membrane|integral component of membrane|,pattern specification process|mammary gland development|mammary gland development|intracellular signal transduction|mammary placode formation|,protein binding|growth factor activity|,10,0,0,10,0.1,0.228,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000034607,POF1B,premature ovarian failure 1B,tight junction|cell junction|,None,actin binding|,10,-0.1,0.376,10,0.1,0.0798,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000068522,AARD,alanine and arginine rich domain containing protein,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000024672,MS4A7,"membrane-spanning 4-domains, subfamily A, member 7",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.0881,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000048834,VSTM2A,V-set and transmembrane domain containing 2A,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000038026,KCNJ9,"potassium inwardly-rectifying channel, subfamily J, member 9",plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|,inward rectifier potassium channel activity|voltage-gated ion channel activity|G-protein activated inward rectifier potassium channel activity|PDZ domain binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000060503,OLFR715,olfactory receptor 715,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000017446,C1QTNF1,C1q and tumor necrosis factor related protein 1,extracellular region|collagen trimer|extracellular space|extracellular space|integral component of plasma membrane|,positive regulation of cytosolic calcium ion concentration|negative regulation of platelet activation|positive regulation of gene expression|regulation of glucose metabolic process|positive regulation of MAPK cascade|protein homooligomerization|positive regulation of protein kinase B signaling|protein heterotrimerization|negative regulation of platelet aggregation|positive regulation of aldosterone secretion|,collagen binding|,10,0.3,1.16,10,-0.2,0.844,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000026241,NPPC,natriuretic peptide type C,extracellular region|extracellular space|secretory granule|,ossification|growth plate cartilage chondrocyte differentiation|growth plate cartilage chondrocyte proliferation|cGMP biosynthetic process|cGMP biosynthetic process|cGMP biosynthetic process|receptor guanylyl cyclase signaling pathway|negative regulation of cell proliferation|post-embryonic development|regulation of cAMP metabolic process|regulation of cGMP metabolic process|positive regulation of cGMP biosynthetic process|regulation of multicellular organism growth|single organism reproductive process|positive regulation of osteoblast differentiation|positive regulation of vasodilation|organ development|regulation of blood vessel size|negative regulation of DNA metabolic process|negative regulation of meiotic cell cycle|negative regulation of meiotic cell cycle|negative regulation of oocyte maturation|negative regulation of oocyte maturation|,receptor binding|receptor binding|hormone activity|neuropeptide hormone activity|protein homodimerization activity|peptide hormone receptor binding|,10,0.2,0.396,10,0,0,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000022155,MROH2B,maestro heat-like repeat family member 2B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0724,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000031101,SASH3,SAM and SH3 domain containing 3,nucleus|cytoplasm|,"positive regulation of immunoglobulin production|positive regulation of T cell cytokine production|positive regulation of adaptive immune response|positive regulation of B cell proliferation|positive regulation of interferon-gamma production|positive regulation of interleukin-10 production|positive regulation of interleukin-2 production|positive regulation of interleukin-4 production|positive regulation of tumor necrosis factor production|positive regulation of T cell proliferation|positive regulation of CD4-positive, alpha-beta T cell differentiation|positive regulation of organ growth|homeostasis of number of cells within a tissue|positive regulation of lymphocyte activation|",None,10,0.4,0.24,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000059762,OLFR767,olfactory receptor 767,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.0927,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000059395,NKAPL,NFKB activating protein-like,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000078131,KRTAP1-3,keratin associated protein 1-3,cellular_component|,biological_process|,molecular_function|,10,0.7,0.139,10,0,0,0,0,0,0.704,0,0,-1.2,1.9
ENSMUSG00000070552,MRGPRX1,"MAS-related GPR, member X1",cellular_component|plasma membrane|membrane|integral component of membrane|,hematopoietic progenitor cell differentiation|signal transduction|G-protein coupled receptor signaling pathway|chemosensory behavior|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000066438,PLEKHD1,"pleckstrin homology domain containing, family D (with coiled-coil domains) member 1",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0414,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000021725,PARP8,"poly (ADP-ribose) polymerase family, member 8",intracellular|,biological_process|,"molecular_function|NAD+ ADP-ribosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|",10,-0.1,0.506,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000063687,PCDHB5,protocadherin beta 5,cytoplasm|plasma membrane|membrane|integral component of membrane|intermediate filament cytoskeleton|,cell adhesion|,None,10,0.2,0.293,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000038903,CCDC68,coiled-coil domain containing 68,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.365,10,0.1,0.0269,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000039891,TXLNB,taxilin beta,cytoplasm|,biological_process|,molecular_function|syntaxin binding|,10,0,0,10,0.1,0.304,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000037813,D630003M21RIK,RIKEN cDNA D630003M21 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000036422,PCDH8,protocadherin 8,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|cell junction|cell projection|synapse|postsynaptic membrane|,somitogenesis|cell adhesion|homophilic cell adhesion|synaptic transmission|morphogenesis of embryonic epithelium|,calcium ion binding|,10,0,0,10,0.1,0.028,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000036110,SLC17A2,"solute carrier family 17 (sodium phosphate), member 2",cellular_component|membrane|integral component of membrane|,transport|ion transport|sodium ion transport|biological_process|transmembrane transport|,molecular_function|symporter activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000061535,C1QTNF7,C1q and tumor necrosis factor related protein 7,extracellular region|collagen trimer|extracellular space|,protein homooligomerization|,molecular_function|,10,-0.1,0.21,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000066672,OLFR417,olfactory receptor 417,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,0,0,9,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000009687,FXYD5,FXYD domain-containing ion transport regulator 5,membrane|integral component of membrane|,transport|ion transport|,actin binding|ion channel activity|cadherin binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000096442,TAAR8A,trace amine-associated receptor 8A,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,trace-amine receptor activity|signal transducer activity|G-protein coupled receptor activity|G-protein coupled amine receptor activity|,10,0.6,1.05,10,-0.1,0.021,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000032705,EXD2,exonuclease 3'-5' domain containing 2,cellular_component|,nucleobase-containing compound metabolic process|biological_process|,molecular_function|nucleic acid binding|nuclease activity|exonuclease activity|3'-5' exonuclease activity|hydrolase activity|,10,-0.2,0.615,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000047583,TYW3,tRNA-yW synthesizing protein 3 homolog (S. cerevisiae),cellular_component|,tRNA processing|biological_process|methylation|,molecular_function|methyltransferase activity|transferase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000045733,SPRN,shadow of prion protein,intracellular|cell|nucleus|nucleolus|cytosol|plasma membrane|membrane|anchored component of membrane|vesicle|,protein import into nucleus|,nucleic acid binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000048294,KRTAP4-13,keratin associated protein 4-13,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,-0.1,0.0237,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000090675,OLFR111,olfactory receptor 111,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0472,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000059336,SLC14A1,"solute carrier family 14 (urea transporter), member 1",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,transport|water transport|water transport|urea transport|urea transport|transmembrane transport|urea transmembrane transport|urea transmembrane transport|,water transmembrane transporter activity|urea transmembrane transporter activity|urea transmembrane transporter activity|urea channel activity|,10,-0.2,0.0241,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000056912,1700017N19RIK,RIKEN cDNA 1700017N19 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.136,10,0.4,1.55,0,0,0,0.704,0,0,-0.9,1.9
ENSMUSG00000025938,SLCO5A1,"solute carrier organic anion transporter family, member 5A1",cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.132,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000089672,GP49A,glycoprotein 49 A,membrane|integral component of membrane|extracellular vesicular exosome|,None,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000030020,PRICKLE2,prickle homolog 2 (Drosophila),nucleus|cytoplasm|membrane|apicolateral plasma membrane|lateral plasma membrane|,neuron projection development|establishment or maintenance of epithelial cell apical/basal polarity|,protein binding|zinc ion binding|metal ion binding|,10,0,0,10,-0.2,0.324,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000078612,1700024P16RIK,RIKEN cDNA 1700024P16 gene,cellular_component|,biological_process|,molecular_function|,10,-0.2,0.517,10,0,0,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000091119,CCDC152,coiled-coil domain containing 152,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.4,1.09,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000032224,FAM81A,"family with sequence similarity 81, member A",cellular_component|,biological_process|,molecular_function|,10,0.1,0.0681,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000075144,OLFR1156,olfactory receptor 1156,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.0723,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000005338,CADM3,cell adhesion molecule 3,plasma membrane|cell-cell junction|membrane|integral component of membrane|cell junction|,cell adhesion|homophilic cell adhesion|heterophilic cell-cell adhesion|protein localization|,protein binding|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.1,2
ENSMUSG00000040121,REP15,RAB15 effector protein,endosome|endosome membrane|membrane|perinuclear region of cytoplasm|recycling endosome|,receptor recycling|transferrin transport|,molecular_function|,10,-0.1,0.231,10,0,0,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000098509,RGS21,regulator of G-protein signalling 21,cytoplasm|plasma membrane|,positive regulation of GTPase activity|,GTPase activator activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000023247,GUCA2A,guanylate cyclase activator 2a (guanylin),extracellular region|extracellular vesicular exosome|,positive regulation of guanylate cyclase activity|,guanylate cyclase activator activity|,10,-0.2,0.474,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000084845,TMEM240,transmembrane protein 240,cellular_component|,biological_process|,molecular_function|,10,1.1,2.27,10,0,0,0,0,0,0.704,0,0,-0.6,2
ENSMUSG00000043913,CCDC60,coiled-coil domain containing 60,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0269,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000047039,OLFR1151,olfactory receptor 1151,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.3,0.257,10,0.1,0.00842,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000023918,GPR115,G protein-coupled receptor 115,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,9,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000028523,TCTEX1D1,Tctex1 domain containing 1,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.119,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000025090,CCDC172,coiled-coil domain containing 172,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.9,0.513,0,0,0,0.704,0,0,-2,1
ENSMUSG00000060780,LRRTM1,leucine rich repeat transmembrane neuronal 1,endoplasmic reticulum|plasma membrane|membrane|integral component of membrane|cell junction|axon|growth cone|synapse|postsynaptic membrane|excitatory synapse|,negative regulation of receptor internalization|locomotory behavior|protein localization to synapse|exploration behavior|synapse organization|synapse organization|synapse organization|long-term synaptic potentiation|,molecular_function|,10,0.2,0.324,10,0,0,0,0,0,0.704,0,0,-1.1,1.8
ENSMUSG00000068263,EFCC1,EF hand and coiled-coil domain containing 1,cellular_component|,biological_process|,molecular_function|calcium ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000046846,SPESP1,sperm equatorial segment protein 1,acrosomal vesicle|cell|cytoplasmic vesicle|,multicellular organismal development|acrosome reaction|fusion of sperm to egg plasma membrane|,protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000044505,LINGO4,leucine rich repeat and Ig domain containing 4,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000050447,LYPD6,LY6/PLAUR domain containing 6,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000026479,LAMC2,"laminin, gamma 2",extracellular region|proteinaceous extracellular matrix|basement membrane|basement membrane|laminin-2 complex|laminin-5 complex|extracellular space|cell cortex|membrane|perinuclear region of cytoplasm|,cell adhesion|,protein binding|heparin binding|,10,-0.1,0.34,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000049565,AKNAD1,AKNA domain containing 1,cytoplasm|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000047606,ANKRD34C,ankyrin repeat domain 34C,cellular_component|,biological_process|,molecular_function|,10,0,0,9,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000031654,CBLN1,cerebellin 1 precursor protein,extracellular region|cell|plasma membrane|membrane|cell junction|synapse|postsynaptic membrane|,heterophilic cell-cell adhesion|protein secretion|cerebellar granule cell differentiation|positive regulation of synapse assembly|positive regulation of synapse assembly|,protein binding|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000032671,A930018P22RIK,RIKEN cDNA A930018P22 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.2,0.369,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000033578,TMEM35,transmembrane protein 35,cellular_component|peroxisome|membrane|integral component of membrane|cytoplasmic vesicle|,biological_process|,molecular_function|,9,-0.7,0.103,9,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000044712,SLC38A6,"solute carrier family 38, member 6",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,1.1,2.97,10,0,0,0,0,0,0.704,0,0,-0.7,2
ENSMUSG00000075570,KRT26,keratin 26,intermediate filament|,biological_process|,structural molecule activity|,10,-0.1,0.143,10,0,0,0,0,0,0.704,0,0,-1.2,1.9
ENSMUSG00000044322,DSC1,desmocollin 1,plasma membrane|membrane|integral component of membrane|cell junction|desmosome|extracellular vesicular exosome|,cell adhesion|homophilic cell adhesion|,calcium ion binding|protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000019909,FAM162B,"family with sequence similarity 162, member B",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.197,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000061531,TMEM236,transmembrane protein 236,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.3,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000056306,SERTM1,serine rich and transmembrane domain containing 1,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,0.116,10,0,0,0,0,0,0.704,0,0,-1.4,1.8
ENSMUSG00000063232,SERPINA11,"serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11",cellular_component|extracellular region|extracellular space|,negative regulation of peptidase activity|negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|peptidase inhibitor activity|,10,0,0,10,0.1,0.0217,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000035095,FAM167A,"family with sequence similarity 167, member A",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.9,1.02,0,0,0,0.704,0,0,-1,2
ENSMUSG00000044056,EFCAB9,EF-hand calcium binding domain 9,cellular_component|,biological_process|,molecular_function|calcium ion binding|,10,0.1,0.0519,10,-0.1,0.22,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000038246,FAM50B,"family with sequence similarity 50, member B",nucleus|,None,None,10,0.1,0.441,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000068696,GPR88,G-protein coupled receptor 88,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|locomotory behavior|neuronal action potential|neuromuscular process controlling balance|,signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0,0,10,0.1,0.269,0,0,0,0.704,0,0,-1.3,1.8
ENSMUSG00000036587,FUT7,fucosyltransferase 7,Golgi apparatus|membrane|membrane|integral component of membrane|,"CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|leukocyte migration involved in immune response|protein glycosylation|","alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000031963,BMPER,BMP-binding endothelial regulator,extracellular region|extracellular space|,blood vessel endothelial cell proliferation involved in sprouting angiogenesis|regulation of endothelial cell migration|negative regulation of BMP signaling pathway|endothelial cell activation|inner ear development|regulation of pathway-restricted SMAD protein phosphorylation|positive regulation of ERK1 and ERK2 cascade|,protein binding|,10,-1.1,0.793,10,-0.1,0.0331,0,0,0,0.704,0,0,-2,0.7
ENSMUSG00000030325,KLRB1C,killer cell lectin-like receptor subfamily B member 1C,plasma membrane|integral component of plasma membrane|external side of plasma membrane|membrane|integral component of membrane|,natural killer cell activation|positive regulation of natural killer cell mediated cytotoxicity|,receptor activity|carbohydrate binding|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000032360,HCRTR2,hypocretin (orexin) receptor 2,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|phospholipase C-activating G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|feeding behavior|circadian sleep/wake cycle process|,signal transducer activity|G-protein coupled receptor activity|orexin receptor activity|orexin receptor activity|peptide hormone binding|,10,0.1,0.127,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000044040,OLFR1497,olfactory receptor 1497,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000022715,CLDN26,claudin 26,plasma membrane|membrane|integral component of membrane|apical plasma membrane|apicolateral plasma membrane|,biological_process|,molecular_function|,10,-0.1,0.161,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000063137,OLFR177,olfactory receptor 177,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.9,1.37,0,0,0,0.704,0,0,-0.7,2
ENSMUSG00000072875,GPR27,G protein-coupled receptor 27,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|,signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.8
ENSMUSG00000051506,WDFY4,WD repeat and FYVE domain containing 4,cellular_component|,biological_process|,molecular_function|,10,0.7,2.07,10,0,0,0,0,0,0.704,0,0,-0.6,2
ENSMUSG00000024254,ABCG8,"ATP-binding cassette, sub-family G (WHITE), member 8",membrane|integral component of membrane|apical plasma membrane|apical plasma membrane|,ATP catabolic process|transport|excretion|excretion|negative regulation of intestinal phytosterol absorption|phospholipid transport|sterol transport|intestinal cholesterol absorption|cholesterol efflux|cholesterol efflux|cholesterol homeostasis|cholesterol homeostasis|negative regulation of intestinal cholesterol absorption|sterol homeostasis|,nucleotide binding|ATP binding|sterol transporter activity|ATPase activity|cholesterol transporter activity|cholesterol transporter activity|protein heterodimerization activity|,10,0,0,10,-0.3,0.761,0,0,0,0.704,0,0,-1.8,1
ENSMUSG00000074681,DEFB23,defensin beta 23,cellular_component|extracellular region|,defense response|biological_process|defense response to bacterium|,molecular_function|,10,0,0,10,0.2,0.374,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000049526,TMEM202,transmembrane protein 202,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.1,0.0522,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000047564,KRTAP3-1,keratin associated protein 3-1,cellular_component|intermediate filament|keratin filament|,biological_process|,molecular_function|structural molecule activity|,10,-1,0.061,10,0,0,0,0,0,0.704,0,0,-2,1.3
ENSMUSG00000039838,SLC45A1,"solute carrier family 45, member 1",cellular_component|membrane|integral component of membrane|,transport|carbohydrate transport|glucose transport|hexose transmembrane transport|transmembrane transport|,glucose transmembrane transporter activity|symporter activity|,10,0,0,10,-0.7,0.938,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000035932,OLFR750,olfactory receptor 750,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.4,1.31,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000020191,4930415F15RIK,RIKEN cDNA 4930415F15 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.00586,10,0.1,0.14,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000036770,4933433C11RIK,RIKEN cDNA 4933433C11 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.2,0.249,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000043461,SPTSSB,"serine palmitoyltransferase, small subunit B",endoplasmic reticulum|membrane|integral component of membrane|serine C-palmitoyltransferase complex|,lipid metabolic process|sphingolipid metabolic process|biological_process|,serine C-palmitoyltransferase activity|,10,0,0,10,0.1,0.237,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000068428,GMNC,geminin coiled-coil domain containing,cellular_component|nucleus|,DNA replication|cell cycle|cell proliferation|,molecular_function|,10,0.1,0.235,10,0,0,0,0,0,0.704,0,0,-1.6,1.3
ENSMUSG00000061974,CLDN24,claudin 24,plasma membrane|tight junction|membrane|integral component of membrane|apical plasma membrane|cell junction|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000045790,CCDC149,coiled-coil domain containing 149,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000036557,1700011E24RIK,RIKEN cDNA 1700011E24 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0401,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000059623,OLFR39,olfactory receptor 39,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.062,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000048013,KRT35,keratin 35,extracellular space|intermediate filament|,None,structural molecule activity|,10,-0.1,0.084,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000040729,AK129341,cDNA sequence AK129341,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.203,10,0.1,0.258,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000078657,CRNN,cornulin,membrane|extracellular vesicular exosome|,response to heat|single organismal cell-cell adhesion|,molecular_function|metal ion binding|,10,0.2,1.27,10,-0.2,0.433,0,0,0,0.704,0,0,-1.3,1.5
ENSMUSG00000066671,OLFR220,olfactory receptor 220,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.2,0.646,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000040163,1700034J05RIK,RIKEN cDNA 1700034J05 gene,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0976,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000029093,SORCS2,sortilin-related VPS10 domain containing receptor 2,membrane|integral component of membrane|,transport|,None,10,-0.1,0.184,10,0.3,0.63,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000003934,EFNB3,ephrin B3,plasma membrane|membrane|integral component of membrane|,multicellular organismal development|nervous system development|axon guidance|adult walking behavior|axon choice point recognition|cell differentiation|ephrin receptor signaling pathway|ephrin receptor signaling pathway|,ephrin receptor binding|ephrin receptor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000021612,SLC6A18,"solute carrier family 6 (neurotransmitter transporter), member 18",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|brush border membrane|,amino acid transmembrane transport|transport|neurotransmitter transport|amino acid transport|,transporter activity|neurotransmitter:sodium symporter activity|protein binding|symporter activity|,10,0,0,10,-0.1,0.15,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000052012,OLFR796,olfactory receptor 796,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.0733,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000052336,CX3CR1,chemokine (C-X3-C motif) receptor 1,plasma membrane|membrane|integral component of membrane|neuronal cell body membrane|neuron projection|perinuclear region of cytoplasm|,microglial cell activation involved in immune response|chemotaxis|cell adhesion|signal transduction|G-protein coupled receptor signaling pathway|negative regulation of angiogenesis|cytokine-mediated signaling pathway|cerebral cortex cell migration|negative regulation of cell migration|positive regulation of angiogenesis|macrophage chemotaxis|chemokine-mediated signaling pathway|negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|,signal transducer activity|cytokine receptor activity|G-protein coupled receptor activity|chemokine receptor activity|C-X3-C chemokine receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000005705,AGRP,agouti related protein,extracellular region|extracellular space|Golgi apparatus|Golgi lumen|neuronal cell body|extracellular vesicular exosome|,neuropeptide signaling pathway|neuropeptide signaling pathway|adult feeding behavior|hormone-mediated signaling pathway|eating behavior|regulation of feeding behavior|positive regulation of feeding behavior|,receptor binding|neuropeptide hormone activity|neuropeptide hormone activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000039977,CCDC67,coiled-coil domain containing 67,cytoplasm|deuterosome|,cell projection organization|de novo centriole assembly|,protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000026573,XCL1,chemokine (C motif) ligand 1,extracellular region|extracellular space|intracellular|cell|,"positive regulation of T cell mediated cytotoxicity|positive regulation of leukocyte chemotaxis|negative regulation of T cell cytokine production|positive regulation of T cell cytokine production|positive regulation of immune response to tumor cell|chemotaxis|immune response|cell-cell signaling|response to virus|positive regulation of T cell chemotaxis|positive regulation of T cell chemotaxis|negative regulation of interferon-gamma production|negative regulation of interleukin-2 production|positive regulation of interleukin-10 production|mature natural killer cell chemotaxis|mature natural killer cell chemotaxis|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of innate immune response|negative regulation of transcription, DNA-templated|regulation of inflammatory response|regulation of inflammatory response|release of sequestered calcium ion into cytosol|positive regulation of release of sequestered calcium ion into cytosol|cellular response to interleukin-4|cellular response to transforming growth factor beta stimulus|positive regulation of transforming growth factor beta production|positive regulation of granzyme B production|positive regulation of neutrophil chemotaxis|positive regulation of thymocyte migration|positive regulation of natural killer cell chemotaxis|positive regulation of natural killer cell chemotaxis|positive regulation of granzyme A production|negative regulation of T-helper 1 cell activation|positive regulation of B cell chemotaxis|positive regulation of T-helper 2 cell cytokine production|positive regulation of T-helper 1 cell cytokine production|positive regulation of immunoglobulin production in mucosal tissue|negative regulation of CD4-positive, alpha-beta T cell proliferation|positive regulation of CD4-positive, alpha-beta T cell proliferation|positive regulation of CD8-positive, alpha-beta T cell proliferation|",cytokine activity|chemokine activity|chemokine activity|chemokine receptor binding|chemokine receptor binding|chemokine receptor binding|protein homodimerization activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000078307,AI593442,expressed sequence AI593442,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0.1,0.514,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000078261,GM11596,predicted gene 11596,cellular_component|intermediate filament|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000071185,OLFR1357,olfactory receptor 1357,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.23,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000033316,GALNT9,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"molecular_function|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-0.1,0.149,10,0.1,0.0478,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000032776,MCTP2,"multiple C2 domains, transmembrane 2",membrane|membrane|integral component of membrane|,biological_process|,calcium ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000073591,PCDHB22,protocadherin beta 22,plasma membrane|membrane|integral component of membrane|,cell adhesion|,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000089661,MIA,melanoma inhibitory activity,extracellular region|,cell-matrix adhesion|extracellular matrix organization|,growth factor activity|,9,-0.1,0.0476,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000098133,AUTS2,autism susceptibility candidate 2,cellular_component|,biological_process|,molecular_function|,9,0,0,9,0,0,0,0,0,0.704,0,0,-1.7,1.5
ENSMUSG00000073293,NUDT10,nudix (nucleoside diphosphate linked moiety X)-type motif 10,intracellular|,None,diphosphoinositol-polyphosphate diphosphatase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000062314,OLFR1505,olfactory receptor 1505,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.158,10,0,0,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000070280,SLC22A14,"solute carrier family 22 (organic cation transporter), member 14",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0727,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000025418,BSND,"Bartter syndrome, infantile, with sensorineural deafness (Barttin)",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|basolateral plasma membrane|protein complex|,chloride transport|cellular ion homeostasis|sensory perception of sound|cellular potassium ion homeostasis|cellular chloride ion homeostasis|,chloride channel activity|protein binding|chloride channel regulator activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000046215,RPRML,reprimo-like,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000048794,CCDC37,coiled-coil domain containing 37,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000022229,ATP12A,"ATPase, H+/K+ transporting, nongastric, alpha polypeptide",membrane|integral component of membrane|basolateral plasma membrane|apical plasma membrane|,ATP biosynthetic process|transport|ion transport|cation transport|potassium ion transport|regulation of pH|response to metal ion|response to organic cyclic compound|monovalent inorganic cation transport|proton transport|metal ion transport|potassium ion homeostasis|hydrogen ion transmembrane transport|,"nucleotide binding|protein binding|ATP binding|hydrogen:potassium-exchanging ATPase activity|monovalent inorganic cation transmembrane transporter activity|hydrolase activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|cation-transporting ATPase activity|metal ion binding|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000020945,LYZL6,lysozyme-like 6,cellular_component|extracellular region|,biological_process|metabolic process|cell wall macromolecule catabolic process|,"molecular_function|lysozyme activity|hydrolase activity|hydrolase activity, acting on glycosyl bonds|",10,0.2,0.327,10,-0.1,0.0953,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000090461,ILTIFB,interleukin 10-related T cell-derived inducible factor beta,extracellular region|extracellular space|,None,cytokine activity|,10,-0.1,0.0854,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000091155,SERPINE3,"serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3",cellular_component|,negative regulation of endopeptidase activity|regulation of proteolysis|,serine-type endopeptidase inhibitor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.9,1.2
ENSMUSG00000045824,OLFR574,olfactory receptor 574,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.1,0.223,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000091972,TMEM207,transmembrane protein 207,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.1,0.209,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000039110,MYCBPAP,MYCBP associated protein,cytoplasm|membrane|,multicellular organismal development|spermatogenesis|biological_process|cell differentiation|,None,10,0.1,0.269,10,1,0.743,0,0,0,0.704,0,0,-1.3,2
ENSMUSG00000035183,SLC24A5,"solute carrier family 24, member 5",Golgi apparatus|trans-Golgi network|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|sodium ion transport|calcium ion transport|ion transmembrane transport|sodium ion transmembrane transport|negative regulation of melanin biosynthetic process|response to stimulus|transmembrane transport|calcium ion transmembrane transport|potassium ion transmembrane transport|,"calcium, potassium:sodium antiporter activity|symporter activity|antiporter activity|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000036198,ARHGAP36,Rho GTPase activating protein 36,intracellular|,signal transduction|,molecular_function|GTPase activator activity|,10,-0.1,0.273,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000054013,TMEM179,transmembrane protein 179,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000028804,CSMD2,CUB and Sushi multiple domains 2,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0405,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000063478,TAS2R114,"taste receptor, type 2, member 114",cellular_component|membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|bitter taste receptor activity|,10,0.2,0.43,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000055811,CLDN17,claudin 17,plasma membrane|tight junction|membrane|integral component of membrane|cell junction|,biological_process|,molecular_function|structural molecule activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000059852,KCNG2,"potassium voltage-gated channel, subfamily G, member 2",membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion transmembrane transport|,voltage-gated ion channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.1,0.0595,10,0.1,0.065,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000039903,EVA1C,eva-1 homolog C (C. elegans),cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|carbohydrate binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000053164,GPR21,G protein-coupled receptor 21,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|positive regulation of multicellular organism growth|glucose homeostasis|negative regulation of insulin receptor signaling pathway|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0.1,0.0167,0,0,0,0.704,0,0,-1.1,1.8
ENSMUSG00000058662,OLFR69,olfactory receptor 69,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000090498,KCNB2,"potassium voltage gated channel, Shab-related subfamily, member 2",voltage-gated potassium channel complex|membrane|integral component of membrane|neuronal cell body|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|,10,-0.8,0.273,10,0,0,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000070564,NTN5,netrin 5,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-1,0.703,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000090894,OLFR110,olfactory receptor 110,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.239,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000022755,GPR128,G protein-coupled receptor 128,plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|biological_process|,molecular_function|signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0,0,10,0.6,0.957,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000094500,SMIM18,small integral membrane protein 18,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.3,0.647,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000045232,RLN3,relaxin 3,extracellular region|,positive regulation of cAMP biosynthetic process|,G-protein coupled receptor binding|hormone activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.5
ENSMUSG00000043972,OPN5,opsin 5,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|visual perception|phototransduction|protein-chromophore linkage|response to stimulus|,molecular_function|signal transducer activity|G-protein coupled receptor activity|photoreceptor activity|,10,0,0,10,0.8,1.18,0,0,0,0.704,0,0,-0.7,2
ENSMUSG00000029335,BMP3,bone morphogenetic protein 3,extracellular region|extracellular space|membrane-bounded vesicle|extracellular vesicular exosome|,ossification|multicellular organismal development|cell differentiation|growth|positive regulation of transcription from RNA polymerase II promoter|cartilage development|,cytokine activity|growth factor activity|BMP receptor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000060105,OLFR504,olfactory receptor 504,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.102,10,-0.4,0.9,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000036103,COLEC12,collectin sub-family member 12,collagen trimer|membrane|integral component of membrane|extracellular vesicular exosome|,"pattern recognition receptor signaling pathway|pattern recognition receptor signaling pathway|phagocytosis, recognition|phagocytosis, recognition|immune response|",signaling pattern recognition receptor activity|signaling pattern recognition receptor activity|low-density lipoprotein particle binding|low-density lipoprotein particle binding|carbohydrate binding|metal ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000059463,SPAG11B,sperm associated antigen 11B,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0137,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000024544,LDLRAD4,low density lipoprotein receptor class A domain containing 4,cellular_component|plasma membrane|membrane|integral component of membrane|,biological_process|,molecular_function|,10,-0.3,0.624,10,0,0,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000020096,TBATA,"thymus, brain and testes associated",nucleus|cytoplasm|cytosol|,multicellular organismal development|spermatogenesis|cell differentiation|spermatid differentiation|,protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000024553,GALR1,galanin receptor 1,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|adenylate cyclase-activating G-protein coupled receptor signaling pathway|negative regulation of adenylate cyclase activity|positive regulation of cytosolic calcium ion concentration|neuropeptide signaling pathway|neuropeptide signaling pathway|synaptic transmission|positive regulation of transcription from RNA polymerase II promoter|positive regulation of cortisol secretion|,signal transducer activity|G-protein coupled receptor activity|galanin receptor activity|galanin receptor activity|peptide hormone binding|neuropeptide binding|,10,0.1,0.0965,10,-0.1,0.159,0,0,0,0.704,0,0,-1.8,1.1
ENSMUSG00000029108,PCDH7,protocadherin 7,integral component of plasma membrane|membrane|integral component of membrane|,cell adhesion|biological_process|,protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000026994,GALNT3,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3,Golgi apparatus|membrane|integral component of membrane|perinuclear region of cytoplasm|,protein O-linked glycosylation via serine|protein O-linked glycosylation via threonine|,"polypeptide N-acetylgalactosaminyltransferase activity|calcium ion binding|transferase activity|transferase activity, transferring glycosyl groups|manganese ion binding|metal ion binding|",10,0,0,10,-0.1,0.028,0,0,0,0.704,0,0,-1.1,1.8
ENSMUSG00000043119,OLFR448,olfactory receptor 448,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.0738,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000000544,GPA33,glycoprotein A33 (transmembrane),plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,None,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000060961,SLC4A4,"solute carrier family 4 (anion exchanger), member 4",plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,transport|ion transport|sodium ion transport|anion transport|regulation of pH|inorganic anion transport|bicarbonate transport|bicarbonate transport|sodium ion transmembrane transport|,transporter activity|inorganic anion exchanger activity|protein binding|anion transmembrane transporter activity|sodium:bicarbonate symporter activity|symporter activity|,10,0,0,10,-0.1,0.2,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000032311,NRG4,neuregulin 4,extracellular region|plasma membrane|membrane|integral component of membrane|,None,growth factor activity|,10,-0.1,0.0693,10,0.1,0.0447,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000043850,CLRN1,clarin 1,plasma membrane|microvillus|membrane|integral component of membrane|lamellipodium|,actin filament organization|visual perception|sensory perception of sound|sensory perception of sound|positive regulation of lamellipodium assembly|photoreceptor cell maintenance|cell motility|neuromuscular process controlling balance|response to stimulus|sensory perception of light stimulus|equilibrioception|auditory receptor cell stereocilium organization|auditory receptor cell development|,None,10,0.1,0.13,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000030361,KLRB1A,killer cell lectin-like receptor subfamily B member 1A,plasma membrane|membrane|integral component of membrane|,biological_process|,carbohydrate binding|,10,0,0,10,-0.1,0.00663,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000058975,KCNC1,"potassium voltage gated channel, Shaw-related subfamily, member 1",voltage-gated potassium channel complex|membrane|integral component of membrane|axolemma|dendrite membrane|neuronal cell body membrane|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|kinesin binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000020830,VMO1,vitelline membrane outer layer 1 homolog (chicken),extracellular region|extracellular vesicular exosome|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000059854,HYDIN,"HYDIN, axonemal central pair apparatus protein",cellular_component|cell projection|,epithelial cell development|cilium movement|multicellular organismal development|brain development|ventricular system development|cilium assembly|trachea development|,molecular_function|structural molecule activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000078591,HS3ST4,heparan sulfate (glucosamine) 3-O-sulfotransferase 4,cellular_component|,biological_process|,molecular_function|,10,0.1,0.143,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000031831,DNAAF1,"dynein, axonemal assembly factor 1",nucleus|cytoplasm|plasma membrane|cilium|axoneme|cell projection|,heart looping|cilium movement|regulation of cilium beat frequency|lung development|determination of pancreatic left/right asymmetry|outer dynein arm assembly|inner dynein arm assembly|motile cilium assembly|cilium morphogenesis|left/right pattern formation|axonemal dynein complex assembly|determination of digestive tract left/right asymmetry|determination of liver left/right asymmetry|,dynein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000001763,TSPAN33,tetraspanin 33,plasma membrane|cell surface|membrane|integral component of membrane|tetraspanin-enriched microdomain|,protein maturation|protein maturation|establishment of protein localization to plasma membrane|establishment of protein localization to plasma membrane|,enzyme binding|enzyme binding|,10,0,0,10,0.1,0.0613,0,0,0,0.704,0,0,-1.9,1
ENSMUSG00000049561,OLFR95,olfactory receptor 95,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0.1,0.0433,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000078907,FAM186B,"family with sequence similarity 186, member B",protein complex|,biological_process|,molecular_function|,10,0,0,10,-0.8,0.802,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000046593,TMEM215,transmembrane protein 215,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000056271,LMAN1L,"lectin, mannose-binding 1 like",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0.6,1.02,10,0,0,0,0,0,0.704,0,0,-1,1.9
ENSMUSG00000051354,SAMD3,sterile alpha motif domain containing 3,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0621,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000094066,GM13298,predicted gene 13298,cellular_component|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0769,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000044249,DEFB29,defensin beta 29,extracellular region|,defense response|defense response to bacterium|,None,10,-0.1,0.272,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000068617,EFCAB1,EF hand calcium binding domain 1,cellular_component|,biological_process|,calcium ion binding|metal ion binding|,10,-0.1,0.0509,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000006360,CRIP1,cysteine-rich protein 1 (intestinal),cytoplasm|cytoplasm|,intrinsic apoptotic signaling pathway in response to DNA damage|intrinsic apoptotic signaling pathway in response to DNA damage|response to zinc ion|response to zinc ion|cellular response to antibiotic|cellular response to antibiotic|cellular response to UV-B|cellular response to UV-B|,"AT DNA binding|AT DNA binding|zinc ion binding|zinc ion binding|DNA binding, bending|DNA binding, bending|peptide binding|peptide binding|metal ion binding|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.1,2
ENSMUSG00000053930,SHISA6,shisa family member 6,membrane|integral component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,biological_process|,molecular_function|,10,-0.1,0.0136,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000094035,LDLRAD2,low density lipoprotein receptor A domain containing 2,cellular_component|,biological_process|,molecular_function|,10,0.7,0.817,10,-0.1,0.189,0,0,0,0.704,0,0,-0.8,2
ENSMUSG00000071686,TEX13A,testis expressed 13A,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000026969,FAM166A,"family with sequence similarity 166, member A",nucleus|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.102,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000028976,SLC2A5,"solute carrier family 2 (facilitated glucose transporter), member 5",plasma membrane|membrane|integral component of membrane|apical plasma membrane|extracellular vesicular exosome|,transport|carbohydrate transport|fructose transport|glucose transport|hexose transmembrane transport|transmembrane transport|cellular response to fructose stimulus|,transporter activity|fructose transmembrane transporter activity|glucose transmembrane transporter activity|transmembrane transporter activity|substrate-specific transmembrane transporter activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000059729,OLFR1385,olfactory receptor 1385,membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.185,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000050650,MRGPRA1,"MAS-related GPR, member A1",cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|neuropeptide signaling pathway|synaptic transmission|,signal transducer activity|G-protein coupled receptor activity|neuropeptide receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000040055,GJB6,"gap junction protein, beta 6",cytosol|plasma membrane|gap junction|gap junction|connexon complex|membrane|integral component of membrane|apical plasma membrane|cell junction|,cell communication|sensory perception of sound|negative regulation of cell proliferation|ear morphogenesis|,protein binding|,10,0,0,10,0.1,0.163,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000040498,IGSF23,"immunoglobulin superfamily, member 23",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000002808,EPDR1,ependymin related protein 1 (zebrafish),extracellular region|lysosome|extracellular vesicular exosome|,cell-matrix adhesion|biological_process|,molecular_function|calcium ion binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000041605,5730559C18RIK,RIKEN cDNA 5730559C18 gene,cellular_component|,biological_process|,molecular_function|,10,0.1,0.077,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000013367,IGLON5,IgLON family member 5,cellular_component|extracellular region|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-2,1.1
ENSMUSG00000047793,SNED1,"sushi, nidogen and EGF-like domains 1",extracellular region|extracellular vesicular exosome|,cell-matrix adhesion|biological_process|,calcium ion binding|,10,-0.1,0.0131,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000030450,OCA2,oculocutaneous albinism II,lysosomal membrane|endoplasmic reticulum membrane|endosome membrane|membrane|integral component of membrane|melanosome membrane|,transport|spermatid development|cell proliferation|melanocyte differentiation|melanin biosynthetic process|pigmentation|developmental pigmentation|transmembrane transport|,None,9,0,0,9,0.2,0.809,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000067656,SLC22A27,"solute carrier family 22, member 27",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000051582,OTUD6A,OTU domain containing 6A,cellular_component|,proteolysis|protein K29-linked deubiquitination|protein K11-linked deubiquitination|protein K27-linked deubiquitination|protein K33-linked deubiquitination|,ubiquitin-specific protease activity|peptidase activity|cysteine-type peptidase activity|hydrolase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000062184,HS6ST2,heparan sulfate 6-O-sulfotransferase 2,membrane|integral component of membrane|extracellular vesicular exosome|,"heparan sulfate proteoglycan biosynthetic process, enzymatic modification|","N-acetylglucosamine 6-O-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity|heparan sulfate 2-O-sulfotransferase activity|sulfotransferase activity|HNK-1 sulfotransferase activity|transferase activity|heparan sulfate 6-O-sulfotransferase activity|trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity|1-phenanthrol sulfotransferase activity|3-phenanthrol sulfotransferase activity|4-phenanthrol sulfotransferase activity|trans-3,4-dihydrodiolphenanthrene sulfotransferase activity|9-phenanthrol sulfotransferase activity|2-phenanthrol sulfotransferase activity|phenanthrol sulfotransferase activity|1-hydroxypyrene sulfotransferase activity|galactose 3-O-sulfotransferase activity|proteoglycan sulfotransferase activity|cholesterol sulfotransferase activity|hydroxyjasmonate sulfotransferase activity|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000056203,TAS2R135,"taste receptor, type 2, member 135",membrane|integral component of membrane|integral component of membrane|,detection of chemical stimulus involved in sensory perception of bitter taste|signal transduction|G-protein coupled receptor signaling pathway|response to stimulus|sensory perception of taste|,signal transducer activity|G-protein coupled receptor activity|taste receptor activity|,9,-0.1,0.217,9,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000045052,PRLHR,prolactin releasing hormone receptor,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|G-protein coupled receptor signaling pathway|feeding behavior|feeding behavior|hormone metabolic process|,signal transducer activity|G-protein coupled receptor activity|G-protein coupled receptor activity|neuropeptide Y receptor activity|peptide hormone binding|,10,0,0,10,0.4,0.786,0,0,0,0.704,0,0,-1,1.9
ENSMUSG00000046922,GPR6,G protein-coupled receptor 6,plasma membrane|membrane|integral component of membrane|,sphingosine-1-phosphate signaling pathway|signal transduction|G-protein coupled receptor signaling pathway|positive regulation of cytosolic calcium ion concentration|,signal transducer activity|G-protein coupled receptor activity|sphingosine-1-phosphate receptor activity|,10,-0.1,0.0299,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000040901,KCNK18,"potassium channel, subfamily K, member 18",plasma membrane|plasma membrane|plasma membrane|membrane|integral component of membrane|,transport|ion transport|potassium ion transport|potassium ion transport|regulation of ion transmembrane transport|potassium ion export|cellular response to pH|potassium ion transmembrane transport|,potassium channel activity|protein binding|calcium-activated potassium channel activity|outward rectifier potassium channel activity|,10,0,0,10,-0.2,0.462,0,0,0,0.704,0,0,-1.7,1.2
ENSMUSG00000045126,OLFR1445,olfactory receptor 1445,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.9
ENSMUSG00000074569,GCNT7,glucosaminyl (N-acetyl) transferase family member 7,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,"alpha-1,6-mannosyltransferase activity|alpha-1,2-mannosyltransferase activity|mannosyltransferase activity|alpha-1,3-mannosyltransferase activity|alpha-1,3-galactosyltransferase activity|molecular_function|UDP-glucose:glycoprotein glucosyltransferase activity|glycolipid mannosyltransferase activity|oligosaccharyl transferase activity|dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity|acetylglucosaminyltransferase activity|acetylgalactosaminyltransferase activity|galactosyltransferase activity|fucosyltransferase activity|O antigen polymerase activity|lipopolysaccharide-1,6-galactosyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|cellulose synthase activity|9-phenanthrol UDP-glucuronosyltransferase activity|1-phenanthrol glycosyltransferase activity|9-phenanthrol glycosyltransferase activity|1,2-dihydroxy-phenanthrene glycosyltransferase activity|phenanthrol glycosyltransferase activity|beta-1,4-mannosyltransferase activity|alpha-1,2-galactosyltransferase activity|dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity|lipopolysaccharide-1,5-galactosyltransferase activity|dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity|inositol phosphoceramide synthase activity|glucosyltransferase activity|alpha-(1->3)-fucosyltransferase activity|alpha-(1->6)-fucosyltransferase activity|indole-3-butyrate beta-glucosyltransferase activity|salicylic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase (glucoside-forming) activity|benzoic acid glucosyltransferase activity|chondroitin hydrolase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity|cytokinin 9-beta-glucosyltransferase activity|",10,-0.2,0.432,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000047259,MC4R,melanocortin 4 receptor,cell|nucleus|plasma membrane|membrane|integral component of membrane|,diet induced thermogenesis|energy reserve metabolic process|signal transduction|G-protein coupled receptor signaling pathway|feeding behavior|feeding behavior|regulation of metabolic process|insulin secretion|positive regulation of cAMP biosynthetic process|response to insulin|positive regulation of bone resorption|positive regulation of bone resorption|regulation of feeding behavior|negative regulation of feeding behavior|regulation of grooming behavior|,signal transducer activity|G-protein coupled receptor activity|melanocortin receptor activity|melanocortin receptor activity|melanocyte-stimulating hormone receptor activity|melanocyte-stimulating hormone receptor activity|protein binding|peptide hormone binding|ubiquitin protein ligase binding|neuropeptide binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000035964,TMEM59L,transmembrane protein 59-like,cellular_component|Golgi apparatus|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0.4,1.11,9,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000030954,GP2,glycoprotein 2 (zymogen granule membrane),extracellular region|plasma membrane|membrane|apical plasma membrane|anchored component of membrane|,antigen transcytosis by M cells in mucosal-associated lymphoid tissue|antigen transcytosis by M cells in mucosal-associated lymphoid tissue|,antigen binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000055567,UNC80,unc-80 homolog (C. elegans),cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,-0.1,0.0565,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000022658,TAGLN3,transgelin 3,nucleus|,negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|,molecular_function|,10,0.2,0.628,10,0,0,0,0,0,0.704,0,0,-1,1.9
ENSMUSG00000020723,CACNG4,"calcium channel, voltage-dependent, gamma subunit 4",plasma membrane|voltage-gated calcium channel complex|membrane|integral component of membrane|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|,transport|ion transport|calcium ion transport|transmission of nerve impulse|regulation of ion transmembrane transport|calcium ion transmembrane transport|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|,voltage-gated ion channel activity|voltage-gated calcium channel activity|calcium channel activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000028444,CNTFR,ciliary neurotrophic factor receptor,plasma membrane|membrane|anchored component of membrane|CNTFR-CLCF1 complex|,suckling behavior|brainstem development|sex differentiation|positive regulation of cell proliferation|negative regulation of neuron apoptotic process|skeletal muscle organ development|ciliary neurotrophic factor-mediated signaling pathway|ciliary neurotrophic factor-mediated signaling pathway|,cytokine receptor activity|ciliary neurotrophic factor receptor activity|ciliary neurotrophic factor receptor activity|ciliary neurotrophic factor receptor activity|receptor binding|protein binding|cytokine binding|,10,0.1,0.289,10,-0.1,0.214,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000021943,GDF10,growth differentiation factor 10,extracellular region|extracellular space|,fat cell differentiation|positive regulation of osteoblast differentiation|,cytokine activity|growth factor activity|,10,0,0,10,0.1,0.0332,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000037239,SPRED3,"sprouty-related, EVH1 domain containing 3",plasma membrane|membrane|,inactivation of MAPK activity|multicellular organismal development|regulation of signal transduction|,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.3
ENSMUSG00000075139,OLFR1162,olfactory receptor 1162,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,-0.2,0.736,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000051243,ISLR2,immunoglobulin superfamily containing leucine-rich repeat 2,plasma membrane|cell surface|membrane|integral component of membrane|,multicellular organismal development|nervous system development|positive regulation of axon extension|,protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000049605,OLFR418-PS1,"olfactory receptor 418, pseudogene 1",None,None,None,10,0,0,10,0.1,0.11,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000046793,GPR61,G protein-coupled receptor 61,plasma membrane|membrane|integral component of membrane|receptor complex|,signal transduction|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000017195,ZPBP2,zona pellucida binding protein 2,acrosomal vesicle|zona pellucida receptor complex|extracellular region|nucleus|cell body|,acrosome assembly|binding of sperm to zona pellucida|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000075569,RSPH10B,radial spoke head 10 homolog B (Chlamydomonas),cellular_component|,biological_process|,molecular_function|,10,-0.2,0.105,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000040482,DXO,decapping exoribonuclease,cellular_component|nucleus|,mRNA catabolic process|metabolic process|RNA destabilization|nuclear mRNA surveillance|nucleic acid phosphodiester bond hydrolysis|,"nucleotide binding|3'-5'-exoribonuclease activity|magnesium ion binding|RNA binding|mRNA binding|nuclease activity|exonuclease activity|5'-3' exoribonuclease activity|thiamine-pyrophosphatase activity|5'-3' exonuclease activity|8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity|UDP-2,3-diacylglucosamine hydrolase activity|bis(5'-nucleosyl)-tetraphosphatase activity|dATP pyrophosphohydrolase activity|pyrophosphatase activity|hydrolase activity|dihydroneopterin monophosphate phosphatase activity|dihydroneopterin triphosphate pyrophosphohydrolase activity|RNA pyrophosphohydrolase activity|dITP diphosphatase activity|dTTP diphosphatase activity|XTP diphosphatase activity|ATP-dependent 5'-3' DNA helicase activity|phosphocholine hydrolase activity|metal ion binding|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000074951,OLFR1309,olfactory receptor 1309,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.1,0.467,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000026984,IL1F6,"interleukin 1 family, member 6",extracellular region|extracellular space|,positive regulation of cytokine production|inflammatory response|immune response|positive regulation of interleukin-6 production|,cytokine activity|interleukin-1 receptor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000094845,TMEM95,transmembrane protein 95,cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000041608,ENTPD3,ectonucleoside triphosphate diphosphohydrolase 3,plasma membrane|,nucleoside diphosphate catabolic process|nucleoside triphosphate catabolic process|,hydrolase activity|nucleoside-diphosphatase activity|nucleoside-triphosphatase activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000022832,ROPN1,"ropporin, rhophilin associated protein 1",nucleus|cytoplasm|cytoplasm|sperm midpiece|sperm principal piece|,regulation of protein phosphorylation|sperm motility|cilium organization|sperm capacitation|protein localization to cilium|,None,10,0,0,10,0.2,0.974,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000050587,LRRC4C,leucine rich repeat containing 4C,extracellular space|plasma membrane|membrane|membrane|integral component of membrane|cell junction|synapse|postsynaptic membrane|,regulation of axonogenesis|regulation of axonogenesis|,protein binding|,10,-0.2,0.953,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000031224,MAGEE2,"melanoma antigen, family E, 2",cellular_component|,biological_process|,molecular_function|,10,0.1,0.116,10,0,0,0,0,0,0.704,0,0,-1.4,1.7
ENSMUSG00000040312,CCHCR1,coiled-coil alpha-helical rod protein 1,nucleus|cytoplasm|cytoplasm|centriole|,protein export from nucleus|multicellular organismal development|cell differentiation|,protein binding|,10,0,0,10,0.1,0.0324,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000027200,SEMA6D,"sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D",plasma membrane|membrane|integral component of membrane|,multicellular organismal development|nervous system development|positive regulation of smooth muscle cell migration|negative regulation of smooth muscle cell migration|ventricular system development|ventricular system development|cell differentiation|,receptor activity|protein binding|semaphorin receptor binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000055761,NKAIN3,Na+/K+ transporting ATPase interacting 3,plasma membrane|membrane|integral component of membrane|,None,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000073898,OLFR713,olfactory receptor 713,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.1,0.125,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000044320,1700001O22RIK,RIKEN cDNA 1700001O22 gene,cellular_component|,biological_process|,molecular_function|,9,-0.1,0.0933,9,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000029322,PLAC8,placenta-specific 8,nucleus|,positive regulation of cell proliferation|response to cold|negative regulation of multicellular organism growth|defense response to bacterium|negative regulation of apoptotic process|negative regulation of apoptotic process|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|brown fat cell differentiation|,chromatin binding|protein binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.5
ENSMUSG00000060988,GALNT13,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13,Golgi apparatus|membrane|integral component of membrane|,protein O-linked glycosylation|,"polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,-1,1.13,10,0,0,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000061392,MAGEB5,"melanoma antigen, family B, 5",cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1,2
ENSMUSG00000093839,OLFR462,olfactory receptor 462,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0.8,0.754,10,0,0,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000004707,LY9,lymphocyte antigen 9,membrane|integral component of membrane|,cell adhesion|,receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000041592,SDK2,sidekick homolog 2 (chicken),membrane|integral component of membrane|,cell adhesion|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000024730,MS4A8A,"membrane-spanning 4-domains, subfamily A, member 8A",membrane|integral component of membrane|,None,None,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000023960,ENPP5,ectonucleotide pyrophosphatase/phosphodiesterase 5,extracellular region|plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|,cell communication|metabolic process|nucleotide catabolic process|,catalytic activity|nuclease activity|nucleotide diphosphatase activity|hydrolase activity|phosphoric ester hydrolase activity|T/G mismatch-specific endonuclease activity|retroviral 3' processing activity|metal ion binding|,10,1.3,1.98,10,0.3,0.229,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000072553,GM525,predicted gene 525,cellular_component|extracellular region|,biological_process|,molecular_function|,10,-0.8,0.0732,10,0,0,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000035528,NPFFR2,neuropeptide FF receptor 2,plasma membrane|integral component of plasma membrane|actin cytoskeleton|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|regulation of MAPK cascade|regulation of adenylate cyclase activity|regulation of cAMP-dependent protein kinase activity|,signal transducer activity|G-protein coupled receptor activity|neuropeptide receptor activity|opioid receptor binding|,10,-0.1,0.0622,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000061815,RUFY4,RUN and FYVE domain containing 4,cellular_component|,biological_process|,molecular_function|metal ion binding|,10,0,0,10,0.1,0.0526,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000091636,A330050F15RIK,RIKEN cDNA A330050F15 gene,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.5
ENSMUSG00000029673,AUTS2,autism susceptibility candidate 2,cellular_component|,biological_process|,molecular_function|,10,0.4,0.758,10,-0.1,0.306,0,0,0,0.704,0,0,-1.2,1.7
ENSMUSG00000050030,OLFR728,olfactory receptor 728,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.6,1.4
ENSMUSG00000034919,TTC22,tetratricopeptide repeat domain 22,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.7,1.4
ENSMUSG00000066747,OLFR878,olfactory receptor 878,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000022941,RIPPLY3,ripply3 homolog (zebrafish),cellular_component|nucleus|,"negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-templated|regulation of transcription, DNA-templated|multicellular organismal development|heart development|pharyngeal system development|",protein binding|,9,0,0,9,0,0,0,0,0,0.704,0,0,-1.5,1.7
ENSMUSG00000040447,SPNS2,spinster homolog 2,cellular_component|membrane|integral component of membrane|,B cell homeostasis|lymphocyte homeostasis|regulation of humoral immune response|sphingosine-1-phosphate signaling pathway|sphingolipid metabolic process|transport|lipid transport|T cell homeostasis|regulation of eye pigmentation|lymph node development|transmembrane transport|bone development|lymphocyte migration|,sphingolipid transporter activity|,10,0.2,0.948,10,-0.1,0.279,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000022596,SLURP1,secreted Ly6/Plaur domain containing 1,extracellular region|extracellular space|extracellular vesicular exosome|,cell activation|,molecular_function|cytokine activity|,10,0.1,0.0522,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000047286,OLFR370,olfactory receptor 370,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-1.2,1.55,10,0,0,0,0,0,0.704,0,0,-2,0.9
ENSMUSG00000042796,OLFR1032,olfactory receptor 1032,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.6,1.74,10,0,0,0,0,0,0.704,0,0,-2,0.8
ENSMUSG00000058251,OLFR822,olfactory receptor 822,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,1.3,1.3,10,0.4,0.769,0,0,0,0.704,0,0,-0.9,2
ENSMUSG00000054523,MS4A5,"membrane-spanning 4-domains, subfamily A, member 5",cellular_component|membrane|integral component of membrane|,biological_process|,molecular_function|,9,0,0,10,-0.6,1.37,0,0,0,0.704,0,0,-2,0.6
ENSMUSG00000026358,RGS1,regulator of G-protein signaling 1,cytoplasm|plasma membrane|plasma membrane|,G-protein coupled receptor signaling pathway|negative regulation of signal transduction|termination of G-protein coupled receptor signaling pathway|positive regulation of GTPase activity|,GTPase activator activity|GTPase activator activity|,10,-0.3,0.678,10,0,0,0,0,0,0.704,0,0,-2,0.7
ENSMUSG00000073956,OLFR592,olfactory receptor 592,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,10,-0.2,0.568,10,0,0,0,0,0,0.704,0,0,-1.4,1.5
ENSMUSG00000060371,CALN1,calneuron 1,cytoplasm|Golgi apparatus|plasma membrane|membrane|integral component of membrane|trans-Golgi network membrane|trans-Golgi network membrane|,biological_process|,calcium ion binding|metal ion binding|,10,0,0,10,0.1,0.0305,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000050641,BC048562,cDNA sequence BC048562,cellular_component|,biological_process|,molecular_function|,10,-0.1,0.0236,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000032036,KIRREL3,kin of IRRE like 3 (Drosophila),extracellular region|plasma membrane|membrane|integral component of membrane|axon|dendritic shaft|,neuron migration|inter-male aggressive behavior|principal sensory nucleus of trigeminal nerve development|hemopoiesis|neuron projection morphogenesis|glomerulus morphogenesis|,protein binding|PDZ domain binding|,10,0.1,0.288,10,-0.1,0.111,0,0,0,0.704,0,0,-1.5,1.4
ENSMUSG00000047875,GPR157,G protein-coupled receptor 157,cellular_component|plasma membrane|membrane|integral component of membrane|,signal transduction|cell surface receptor signaling pathway|G-protein coupled receptor signaling pathway|biological_process|,molecular_function|signal transducer activity|transmembrane signaling receptor activity|G-protein coupled receptor activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.6
ENSMUSG00000078532,NKAIN1,Na+/K+ transporting ATPase interacting 1,plasma membrane|membrane|integral component of membrane|,None,None,10,-0.3,1.06,10,0.1,0.0751,0,0,0,0.704,0,0,-1.7,1.1
ENSMUSG00000038143,STOX2,storkhead box 2,cellular_component|,biological_process|,molecular_function|,10,0,0,10,0.1,0.0188,0,0,0,0.704,0,0,-1.2,1.8
ENSMUSG00000030206,GSG1,germ cell-specific gene 1,endoplasmic reticulum|membrane|integral component of membrane|,biological_process|,protein binding|RNA polymerase binding|,10,-0.1,0.238,10,0.1,0.00789,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000064325,HHIP,Hedgehog-interacting protein,extracellular region|plasma membrane|integral component of plasma membrane|cell surface|membrane|,carbohydrate metabolic process|signal transduction|smoothened signaling pathway|neuroblast proliferation|organ morphogenesis|dorsal/ventral pattern formation|negative regulation of signal transduction|negative regulation of angiogenesis|regulation of fibroblast growth factor receptor signaling pathway|negative regulation of smoothened signaling pathway|skeletal system morphogenesis|epithelial tube branching involved in lung morphogenesis|,"catalytic activity|protein binding|zinc ion binding|oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor|metal ion binding|quinone binding|hedgehog family protein binding|",10,-0.1,0.355,10,0,0,0,0,0,0.704,0,0,-2,1
ENSMUSG00000030307,SLC6A11,"solute carrier family 6 (neurotransmitter transporter, GABA), member 11",cytoplasm|integral component of plasma membrane|membrane|integral component of membrane|cell projection|,amino acid transmembrane transport|transport|neurotransmitter transport|gamma-aminobutyric acid transport|sodium ion transmembrane transport|,neurotransmitter:sodium symporter activity|gamma-aminobutyric acid:sodium symporter activity|symporter activity|neurotransmitter binding|,10,-0.2,0.876,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000022025,LECT1,leukocyte cell derived chemotaxin 1,extracellular region|proteinaceous extracellular matrix|membrane|integral component of membrane|,endothelial cell morphogenesis|negative regulation of endothelial cell proliferation|multicellular organismal development|negative regulation of angiogenesis|negative regulation of angiogenesis|negative regulation of angiogenesis|cell differentiation|negative regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of ossification|cartilage development|,None,10,0,0,10,0.2,0.353,0,0,0,0.704,0,0,-1.1,1.9
ENSMUSG00000027524,EDN3,endothelin 3,extracellular region|extracellular space|intracellular|cell|,neural crest cell migration|positive regulation of leukocyte chemotaxis|regulation of systemic arterial blood pressure by endothelin|cell surface receptor signaling pathway|positive regulation of cell proliferation|positive regulation of heart rate|vein smooth muscle contraction|regulation of vasoconstriction|peptide hormone secretion|neuron differentiation|melanocyte differentiation|regulation of cell migration|neutrophil chemotaxis|vasoconstriction|positive regulation of MAP kinase activity|positive regulation of mitosis|positive regulation of hormone secretion|negative regulation of hormone secretion|regulation of neurotransmitter secretion|inositol phosphate-mediated signaling|regulation of developmental pigmentation|regulation of blood vessel size|,hormone activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000021130,GALNT16,UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16,Golgi apparatus|membrane|integral component of membrane|extracellular vesicular exosome|,biological_process|,"molecular_function|polypeptide N-acetylgalactosaminyltransferase activity|transferase activity|transferase activity, transferring glycosyl groups|metal ion binding|",10,0,0,10,0,0,0,0,0,0.704,0,0,-1.9,1.1
ENSMUSG00000005864,CNGA2,cyclic nucleotide gated channel alpha 2,plasma membrane|integral component of plasma membrane|membrane|integral component of membrane|intracellular cyclic nucleotide activated cation channel complex|perikaryon|,"transport|ion transport|cation transport|potassium ion transport|phototransduction, visible light|sensory perception of smell|ion transmembrane transport|regulation of ion transmembrane transport|regulation of membrane potential|response to stimulus|protein homotetramerization|protein heterotetramerization|membrane depolarization|transmembrane transport|potassium ion transmembrane transport|",nucleotide binding|ion channel activity|intracellular cAMP activated cation channel activity|intracellular cAMP activated cation channel activity|intracellular cGMP activated cation channel activity|intracellular cGMP activated cation channel activity|voltage-gated potassium channel activity|calmodulin binding|cAMP binding|cGMP binding|cGMP binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000047959,KCNA3,"potassium voltage-gated channel, shaker-related subfamily, member 3",plasma membrane|voltage-gated potassium channel complex|membrane|integral component of membrane|membrane raft|,transport|ion transport|potassium ion transport|regulation of ion transmembrane transport|protein homooligomerization|transmembrane transport|potassium ion transmembrane transport|,ion channel activity|voltage-gated ion channel activity|voltage-gated potassium channel activity|delayed rectifier potassium channel activity|delayed rectifier potassium channel activity|potassium channel activity|outward rectifier potassium channel activity|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.5,1.6
ENSMUSG00000026090,2010300C02RIK,RIKEN cDNA 2010300C02 gene,cellular_component|,biological_process|,molecular_function|,10,0.2,0.246,10,0,0,0,0,0,0.704,0,0,-1.3,1.6
ENSMUSG00000020728,CEP112,centrosomal protein 112,cytoplasm|centrosome|cytoskeleton|plasma membrane|inhibitory synapse|,receptor localization to synapse|,molecular_function|,10,0,0,10,0.2,0.125,0,0,0,0.704,0,0,-1.5,1.5
ENSMUSG00000029286,ENAM,enamelin,cellular_component|extracellular region|proteinaceous extracellular matrix|,biomineral tissue development|odontogenesis of dentin-containing tooth|amelogenesis|,molecular_function|,10,-0.1,0.253,10,0,0,0,0,0,0.704,0,0,-1.7,1.3
ENSMUSG00000024485,SLC4A9,"solute carrier family 4, sodium bicarbonate cotransporter, member 9",basolateral plasma membrane|apical part of cell|apical part of cell|,anion transport|ion transmembrane transport|,anion:anion antiporter activity|,10,0.1,0.167,10,0,0,0,0,0,0.704,0,0,-1.3,1.7
ENSMUSG00000066262,OLFR640,olfactory receptor 640,plasma membrane|membrane|integral component of membrane|,signal transduction|G-protein coupled receptor signaling pathway|sensory perception of smell|response to stimulus|detection of chemical stimulus involved in sensory perception of smell|,signal transducer activity|G-protein coupled receptor activity|olfactory receptor activity|,9,0,0,9,0,0,0,0,0,0.704,0,0,-1.6,1.6
ENSMUSG00000020264,SLC36A2,"solute carrier family 36 (proton/amino acid symporter), member 2",cytoplasm|plasma membrane|membrane|integral component of membrane|extracellular vesicular exosome|,regulation of proton transport|L-alanine transport|glycine transport|glycine transport|proline transport|proton transport|amino acid export|proline transmembrane transport|proline transmembrane transport|regulation of proline transport|positive regulation of glycine import|L-alpha-amino acid transmembrane transport|,hydrogen:amino acid symporter activity|L-alanine transmembrane transporter activity|glycine transmembrane transporter activity|glycine transmembrane transporter activity|L-proline transmembrane transporter activity|,10,-0.1,0.117,10,0,0,0,0,0,0.704,0,0,-1.8,1.2
ENSMUSG00000022652,MORC1,microrchidia 1,nucleus|,multicellular organismal development|spermatogenesis|cell differentiation|,molecular_function|zinc ion binding|metal ion binding|,10,0,0,10,-0.4,0.857,0,0,0,0.704,0,0,-1.9,1
ENSMUSG00000027376,PROM2,prominin 2,plasma membrane|integral component of plasma membrane|integral component of plasma membrane|microvillus|microvillus|cilium|cilium|cell surface|cell surface|membrane|integral component of membrane|cytoplasmic vesicle|cytoplasmic vesicle|cell projection|microspike|microspike|membrane raft|membrane raft|extracellular vesicular exosome|prominosome|prominosome|,positive regulation of protein phosphorylation|positive regulation of cell projection organization|regulation of Cdc42 GTPase activity|negative regulation of pinocytosis|negative regulation of caveolin-mediated endocytosis|,cholesterol binding|cholesterol binding|,10,0,0,10,0,0,0,0,0,0.704,0,0,-1.4,1.7