Isotype,variant,MCD Score TUBß8,V353I,0.188188381 TUBa1A,I238V,0.215529563 TUBa1A,I219V,0.215876414 TUBß8,I4L,0.221251192 TUBa1A,D127E,0.245956857 TUBß8,A352S,0.247709077 TUBß1,R307H,0.253453854 TUBß8,M330I,0.280641477 TUBß5,V353I,0.280780221 TUBa1A,S54N,0.300132328 TUBß8,R2K,0.31181383 TUBa1A,A270S,0.32610157 TUBa1A,V353I,0.335779461 TUBa1A,I188L,0.341419148 TUBß3,M323V,0.342945625 TUBß8,F200L,0.352795897 TUBß8,V175M,0.354377193 TUBa1A,I5L,0.357402023 TUBa1A,V409I,0.371734003 TUBa1A,R214H,0.372693731 TUBß8,M300I,0.375004734 TUBß5,Y222F,0.375456582 TUBß8,V255M,0.376630515 TUBa1A,A270T,0.383882229 TUBß8,I210V,0.384088768 TUBß8,V179M,0.385018177 TUBß8,Q245H,0.385860822 TUBß8,N348S,0.387464871 TUBß8,Q334E,0.395161063 TUBß8,D417N,0.401416763 TUBa1A,N329S,0.414722117 TUBß8,E410K,0.422573174 TUBa4A,K430N,0.423322587 TUBa1A,A19T,0.43200985 TUBß3,Q292E,0.432143074 TUBß8,R241H,0.432504447 TUBß8,R262Q,0.441254522 TUBß4A,V255I,0.44137542 TUBß2B,A248V,0.460248606 TUBß3,T238A,0.471204922 TUBß8,E205K,0.474658064 TUBß4A,R2Q,0.476394583 TUBß8,F367L,0.478122454 TUBß8,E108K,0.481479767 TUB1,F21L,0.485933474 TUBß4A,A352T,0.490585672 TUBa1A,R402H,0.493775814 TUBß8,V229A,0.496175614 TUBa1A,R123H,0.501169731 TUBß2B,S278G,0.506458037 TUBa4A,G43V,0.510147256 TUBa1A,E429Q,0.511043627 TUBß8,T238M,0.514257761 TUBa1A,G59S,0.514702729 TUBß8,M363T,0.518849915 TUBß8,P358A,0.519112199 TUBß3,M388V,0.520043867 TUBa1A,V118L,0.520607391 TUBß8,S176L,0.523405959 TUBß2A,A248V,0.524243932 TUBß4A,N414K,0.524866606 TUBß2B,A248T,0.527085578 TUBa1A,R2H,0.527392028 TUBa1A,L286F,0.527628794 TUBa1A,A333V,0.52954607 TUBa1A,V235L,0.529622516 TUBa1A,L92V,0.530725933 TUBß3,D417N,0.536953773 TUBß4A,A271T,0.537006506 TUBß8,R2M,0.537853907 TUBa1A,K326N,0.540283403 TUBß8,T285P,0.544096344 TUBß3,G98S,0.548970044 TUBß1,R359W,0.551254628 TUBß8,D417Y,0.553980885 TUBß2B,D417N,0.55507467 TUBa1A,N101S,0.556925117 TUBß3,G82R,0.558538611 TUBa1A,R264H,0.560275611 TUBß4A,M300I,0.562508426 TUBß5,Q15K,0.568024604 TUB1,I257F,0.569851687 TUBß8,P61T,0.570931084 TUBa1A,R422H,0.571301079 TUBa1A,V435A,0.571530287 TUBß4A,R391H,0.572340448 TUBß8,R391C,0.57299884 TUBa1A,T56M,0.576687175 TUBß5,M299V,0.577460392 TUBß3,E410K,0.577926682 TUBß3,A302T,0.580890495 TUBß4B,R391H,0.581114202 TUBß2B,M388V,0.58118891 TUBa1A,P72S,0.581877045 TUBß4A,V179L,0.583934016 TUBß3,T178M,0.586851472 TUBß8,G98R,0.587121384 TUBa1A,E113K,0.588993919 TUBß4A,M388I,0.590029349 TUBa1A,R320H,0.59363463 TUBß1,T274M,0.594122426 TUB1,T331P,0.595779051 TUBß2B,E421K,0.595806659 TUBß1,Q43P,0.596626195 TUBa1A,H107R,0.596696444 TUBß8,R262W,0.607346134 TUBa1A,S419L,0.607663584 TUBß2A,D417N,0.611353791 TUBß4A,M323R,0.613228474 TUBa1A,A369T,0.614494178 TUBß4A,F367L,0.614838132 TUBß8,C354Y,0.61726505 TUBß3,A302V,0.619845326 TUBß8,P358L,0.621899401 TUBa1A,Y161H,0.622141716 TUBß5,T221I,0.624526415 TUBa1A,A387V,0.626507239 TUBß4A,M388V,0.627593175 TUBa1A,E27Q,0.629278365 TUBß2B,N256S,0.633370985 TUBß3,R46G,0.634930175 TUBß4A,G244S,0.636789481 TUBa1A,R123C,0.637793865 TUBß3,E288K,0.638630855 TUBa1A,E55K,0.638792473 TUBß3,D417H,0.639301496 TUBß4A,Q292K,0.639603977 TUBß4A,E410K,0.644549504 TUBa1A,G366R,0.648324396 TUBß4A,R2G,0.650335467 TUBa1A,V409A,0.650936436 TUBß4A,A248D,0.65202534 TUBa1A,R390H,0.65231186 TUBß2B,D327G,0.652811366 TUBß3,G71R,0.653875256 TUBß2B,R241H,0.654571673 TUBa1A,D218Y,0.655901537 TUBß4A,H190Y,0.659211718 TUBß4A,F367I,0.662332097 TUBß3,E410V,0.662365762 TUBß3,S230L,0.663257236 TUBß2A,N247K,0.663327828 TUBa1A,R402L,0.665251009 TUBa4A,R320H,0.665427489 TUBß4A,R262H,0.66842396 TUBß3,R262H,0.672408727 TUBß2B,R380S,0.673244622 TUBß3,E205K,0.676448678 TUBß2B,C354R,0.676744546 TUBß4A,D249N,0.677838551 TUBß2B,P173L,0.679941615 TUBß4A,T178M,0.680033611 TUBß4B,R391C,0.6804264 TUBß2B,F265L,0.68107761 TUBa1A,L70S,0.681663548 TUBß5,P287L,0.681940276 TUBß4A,R2W,0.685218867 TUBß3,P357L,0.686698925 TUB1,S259L,0.687809113 TUBß3,R62Q,0.691338899 TUBa1A,R2S,0.694064723 TUBa1A,T150I,0.695264225 TUBß4A,A314V,0.695541134 TUBß2B,R380L,0.697605785 TUBa1A,L397P,0.698442829 TUBß2B,G140A,0.69929575 TUBß2B,G13A,0.707458002 TUBß4A,V180G,0.708004264 TUB1,D68N,0.711864987 TUBß4A,P182T,0.712062685 TUBa1A,M425K,0.717445877 TUBß4A,C239F,0.718684322 TUBa4A,T145P,0.719007434 TUBß2B,I210T,0.719716749 TUBß3,R262A,0.722861664 TUBß2B,R380C,0.723231038 TUBa1A,R422C,0.731807165 TUBß4A,G244D,0.733198282 TUBa1A,R390C,0.733856413 TUBß4A,T178R,0.734048501 TUB1,R341W,0.736053368 TUBa4A,R215C,0.737272705 TUBß3,R380C,0.739266449 TUBß2B,C239F,0.739295936 TUBa1A,R402C,0.739514045 TUBß2B,T312M,0.740219439 TUBa4A,A383T,0.740951772 TUBß4A,G96R,0.743187239 TUBß4A,M388T,0.743666097 TUBa1A,P263T,0.746045768 TUBß1,F260S,0.746964267 TUBa1A,G436R,0.747987848 TUBß2B,P171T,0.753716915 TUBa1A,V303G,0.762131473 TUBß4A,D355V,0.764560881 TUBß2B,G98R,0.765070131 TUBß2B,I202T,0.767631985 TUBß2B,S172P,0.769307096 TUBß4A,F394C,0.769606545 TUBa1A,V137D,0.769753562 TUBß4A,R156L,0.774898139 TUB1,L387P,0.781609983 TUBß4A,G244V,0.788246851 TUBß2B,D249H,0.789482282 TUBß4A,C354Y,0.791376976 TUBß4A,R282P,0.791408037 TUBa1A,V371E,0.793094909 TUBa1A,R64W,0.795539941 TUBa1A,S158L,0.79984071 TUBa1A,Y210C,0.806179292 TUBa1A,C25F,0.807679729 TUBa1A,C200Y,0.807918164 TUBa1A,D396Y,0.808207373 TUBß3,R262C,0.815247964 TUBa1A,P173L,0.818349438 TUBa1A,R264C,0.829727279 TUBß1,R318W,0.837411635 TUBß2B,L207P,0.839636289 TUB1,Y92C,0.847817188 TUBß2B,G369V,0.860925485 TUBa4A,R320C,0.86451789 TUBß2B,L228P,0.874206356 TUBß2B,L117P,0.883278402