Pathway identifier,Pathway name,#Entities found,#Entities total,Entities ratio,Entities pValue,Entities FDR,#Reactions found,#Reactions total,Reactions ratio,Species identifier,Species name,Submitted entities found,Mapped entities,Found reaction identifiers R-HSA-606279,"Deposition of new CENPA-containing nucleosomes at the centromere",31,54,0.0036802289920261706,1.1102230246251565E-16,4.3298697960381105E-15,4,4,3.0859435272334514E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HJURP;CASC5;CENPA;HIST2H4A;HIST1H2AE;HIST1H2AD;OIP5;STRA13;CENPU;CENPW;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;MIS18A;CENPI;CENPK;CENPL;HIST1H2BF;CENPM;HIST1H4H;HIST1H2BE;CENPN;CENPO;HIST1H2BG;HIST1H4C;HIST1H2BB;CENPQ;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-606349;R-HSA-606287;R-HSA-606289;R-HSA-606326" R-HSA-774815,"Nucleosome assembly",31,54,0.0036802289920261706,1.1102230246251565E-16,4.3298697960381105E-15,4,4,3.0859435272334514E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HJURP;CASC5;CENPA;HIST2H4A;HIST1H2AE;HIST1H2AD;OIP5;STRA13;CENPU;CENPW;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;MIS18A;CENPI;CENPK;CENPL;HIST1H2BF;CENPM;HIST1H4H;HIST1H2BE;CENPN;CENPO;HIST1H2BG;HIST1H4C;HIST1H2BB;CENPQ;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-606349;R-HSA-606287;R-HSA-606289;R-HSA-606326" R-HSA-141444,"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal",38,94,0.006406324541675185,1.1102230246251565E-16,4.3298697960381105E-15,4,4,3.0859435272334514E-4,9606,Homo sapiens,"ERCC6L;ZWILCH;CDCA8;CASC5;BUB1B;CENPA;AURKB;SKA1;CDC20;DSN1;NUF2;KNTC1;BUB3;SPDL1;BUB1;CENPU;PLK1;NDC80;ZWINT;SGO1;CENPE;SGO2;CENPF;KIF18A;CENPI;INCENP;CENPK;CENPL;CENPM;BIRC5;CENPN;KIF2C;CENPO;DOCK2;CENPQ;SPC24;MAD2L1;SPC25","","R-HSA-141409;R-HSA-141431;R-HSA-141422;R-HSA-141439" R-HSA-141424,"Amplification of signal from the kinetochores",38,94,0.006406324541675185,1.1102230246251565E-16,4.3298697960381105E-15,4,4,3.0859435272334514E-4,9606,Homo sapiens,"ERCC6L;ZWILCH;CDCA8;CASC5;BUB1B;CENPA;AURKB;SKA1;CDC20;DSN1;NUF2;KNTC1;BUB3;SPDL1;BUB1;CENPU;PLK1;NDC80;ZWINT;SGO1;CENPE;SGO2;CENPF;KIF18A;CENPI;INCENP;CENPK;CENPL;CENPM;BIRC5;CENPN;KIF2C;CENPO;DOCK2;CENPQ;SPC24;MAD2L1;SPC25","","R-HSA-141409;R-HSA-141431;R-HSA-141422;R-HSA-141439" R-HSA-69618,"Mitotic Spindle Checkpoint",40,111,0.0075649151502760175,1.1102230246251565E-16,4.3298697960381105E-15,7,7,5.40040117265854E-4,9606,Homo sapiens,"ERCC6L;ZWILCH;CDCA8;CASC5;BUB1B;CENPA;AURKB;SKA1;CDC20;DSN1;NUF2;KNTC1;BUB3;SPDL1;BUB1;CENPU;UBE2C;PLK1;NDC80;ZWINT;SGO1;CENPE;SGO2;CENPF;KIF18A;CENPI;INCENP;UBE2S;CENPK;CENPL;CENPM;BIRC5;CENPN;KIF2C;CENPO;DOCK2;CENPQ;SPC24;MAD2L1;SPC25","","R-HSA-141409;R-HSA-141431;R-HSA-141429;R-HSA-141422;R-HSA-141439;R-HSA-141423;R-HSA-141437" R-HSA-69206,"G1/S Transition",39,150,0.010222858311183807,1.1102230246251565E-16,4.3298697960381105E-15,57,61,0.004706063879031014,9606,Homo sapiens,"MCM7;MCM8;PRIM1;MCM10;LIN9;TYMS;CKS1B;CCNB1;ORC6;CDC45;ORC1;E2F1;TK1;FBXO5;CDT1;RRM2;CDC7;CDC6;CDC25A;CCNA2;POLA2;RBL1;DBF4;CCNE2;POLE2;CDK2;CDK1;MCM5;MCM2","","R-HSA-187520;R-HSA-8961934;R-HSA-8961678;R-HSA-8961920;R-HSA-8961665;R-HSA-8962050;R-HSA-8961671;R-HSA-8961688;R-HSA-8961946;R-HSA-8848414;R-HSA-187545;R-HSA-8961961;R-HSA-187552;R-HSA-8961952;R-HSA-8961699;R-HSA-69299;R-HSA-68914;R-HSA-8848436;R-HSA-68917;R-HSA-187574;R-HSA-68916;R-HSA-187575;R-HSA-8961982;R-HSA-68919;R-HSA-68918;R-HSA-8961840;R-HSA-8932400;R-HSA-188345;R-HSA-69562;R-HSA-188350;R-HSA-8961972;R-HSA-8961846;R-HSA-69191;R-HSA-69195;R-HSA-68940;R-HSA-69199;R-HSA-8961863;R-HSA-8961991;R-HSA-157906;R-HSA-8961874;R-HSA-8961619;R-HSA-68954;R-HSA-8961620;R-HSA-188386;R-HSA-68960;R-HSA-113504;R-HSA-188390;R-HSA-113638;R-HSA-8961632;R-HSA-8961888;R-HSA-113643;R-HSA-8961636;R-HSA-8961895;R-HSA-8961915;R-HSA-8961651;R-HSA-8961907;R-HSA-8962039" R-HSA-453279,"Mitotic G1 phase and G1/S transition",49,173,0.01179036325223199,1.1102230246251565E-16,4.3298697960381105E-15,92,99,0.007637710229902793,9606,Homo sapiens,"CDKN1C;TOP2A;MCM7;MCM8;PRIM1;MCM10;LIN9;TYMS;CKS1B;CCNB1;ORC6;CDC45;ORC1;E2F1;MYBL2;TK1;FBXO5;CDKN2D;CDT1;RRM2;CDC7;CDC6;CDC25A;CCNA2;POLA2;RBL1;DBF4;CCNE2;POLE2;CDK2;CDK1;MCM5;MCM2","","R-HSA-187520;R-HSA-8964492;R-HSA-1227671;R-HSA-8961934;R-HSA-8961678;R-HSA-8942607;R-HSA-8961920;R-HSA-8961665;R-HSA-8962050;R-HSA-8964482;R-HSA-8961671;R-HSA-8961688;R-HSA-8961946;R-HSA-1363328;R-HSA-1363331;R-HSA-8848414;R-HSA-8964498;R-HSA-187545;R-HSA-8961961;R-HSA-187552;R-HSA-8964525;R-HSA-9018017;R-HSA-8961952;R-HSA-8964513;R-HSA-8961699;R-HSA-69299;R-HSA-68914;R-HSA-8848436;R-HSA-68917;R-HSA-187574;R-HSA-68916;R-HSA-187575;R-HSA-8961982;R-HSA-68919;R-HSA-68918;R-HSA-8961840;R-HSA-8932400;R-HSA-8964531;R-HSA-188345;R-HSA-69562;R-HSA-188350;R-HSA-8961972;R-HSA-8961846;R-HSA-182594;R-HSA-1362261;R-HSA-69191;R-HSA-69195;R-HSA-1362270;R-HSA-68940;R-HSA-69199;R-HSA-8964550;R-HSA-8961863;R-HSA-8961991;R-HSA-8941895;R-HSA-157906;R-HSA-8941915;R-HSA-8964561;R-HSA-8961874;R-HSA-8942803;R-HSA-8961619;R-HSA-68954;R-HSA-8961620;R-HSA-1363274;R-HSA-8964567;R-HSA-188386;R-HSA-68960;R-HSA-113504;R-HSA-188390;R-HSA-8964588;R-HSA-1363314;R-HSA-113638;R-HSA-8978926;R-HSA-8961632;R-HSA-8961888;R-HSA-69227;R-HSA-113643;R-HSA-8961636;R-HSA-8964580;R-HSA-8961895;R-HSA-8961915;R-HSA-1363303;R-HSA-8964475;R-HSA-8964465;R-HSA-8961651;R-HSA-8961907;R-HSA-1363311;R-HSA-1226094;R-HSA-8942836;R-HSA-1226095;R-HSA-1363306;R-HSA-8962039;R-HSA-8964471" R-HSA-73886,"Chromosome Maintenance",46,138,0.009405029646289103,1.1102230246251565E-16,4.3298697960381105E-15,35,38,0.002931646350871779,9606,Homo sapiens,"FEN1;HJURP;CASC5;CHTF18;HIST1H2AE;HIST1H2AD;OIP5;STRA13;RFC3;RFC4;LIG1;H2AFZ;RFC2;HIST1H2AK;H2AFX;HIST2H2BB;CCNA2;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;PRIM1;HIST1H2BL;HIST1H2BK;CENPA;HIST2H4A;POLD1;RAD54L;CENPU;CENPW;HIST1H4L;H2BFS;POLA2;HIST1H4B;MIS18A;CENPI;CDK2;CENPK;CDK1;CENPL;CENPM;HIST1H4H;CENPN;CENPO;HIST1H4C;CENPQ;HIST1H4D;HIST1H4E;WRAP53","","R-HSA-606349;R-HSA-606287;R-HSA-9670101;R-HSA-181450;R-HSA-164616;R-HSA-164617;R-HSA-164620;R-HSA-163090;R-HSA-9670149;R-HSA-606289;R-HSA-174427;R-HSA-163099;R-HSA-163096;R-HSA-174425;R-HSA-174438;R-HSA-174439;R-HSA-9668597;R-HSA-9686521;R-HSA-174441;R-HSA-174446;R-HSA-174447;R-HSA-174444;R-HSA-174445;R-HSA-9670114;R-HSA-174451;R-HSA-174448;R-HSA-163120;R-HSA-9668902;R-HSA-174452;R-HSA-174456;R-HSA-9668904;R-HSA-176702;R-HSA-176700;R-HSA-606326;R-HSA-9007926" R-HSA-5693567,"HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)",35,124,0.008450896203911947,1.1102230246251565E-16,4.3298697960381105E-15,37,42,0.003240240703595124,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;BRCA2;HIST2H4A;RAD51AP1;BRIP1;EME1;EXO1;POLD1;CLSPN;GEN1;RFC3;RFC4;RFC2;HIST1H4L;XRCC2;XRCC3;H2AFX;HIST2H2BB;H2BFS;CCNA2;HIST1H4B;RAD51;POLE2;CDK2;HIST1H2BF;TIMELESS;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5684887;R-HSA-5684052;R-HSA-5693589;R-HSA-5684882;R-HSA-5685011;R-HSA-5686483;R-HSA-5693584;R-HSA-5686430;R-HSA-5685341;R-HSA-5693593;R-HSA-5685318;R-HSA-5685319;R-HSA-5686469;R-HSA-5684096;R-HSA-5686657;R-HSA-5685838;R-HSA-5693580;R-HSA-5684108;R-HSA-5686410;R-HSA-5684875;R-HSA-5686475;R-HSA-5693620;R-HSA-5686642;R-HSA-5684081;R-HSA-5686398;R-HSA-5693564;R-HSA-5685242;R-HSA-5693561;R-HSA-5693542;R-HSA-5684071;R-HSA-5685156;R-HSA-5693539;R-HSA-5685985;R-HSA-5685230;R-HSA-5685994;R-HSA-5686440;R-HSA-5693608" R-HSA-2500257,"Resolution of Sister Chromatid Cohesion",49,134,0.0091324200913242,1.1102230246251565E-16,4.3298697960381105E-15,7,8,6.171887054466903E-4,9606,Homo sapiens,"ERCC6L;ZWILCH;CDCA5;CDCA8;CASC5;BUB1B;CENPA;AURKB;SKA1;CDC20;CCNB2;TUBA1C;TUBB6;CCNB1;TUBA1B;DSN1;TUBB3;NUF2;KNTC1;BUB3;SPDL1;BUB1;CENPU;PLK1;TUBB4B;NDC80;ZWINT;SGO1;CENPE;SGO2;CENPF;KIF18A;CENPI;INCENP;CENPK;CENPL;CDK1;CENPM;BIRC5;CENPN;KIF2C;CENPO;DOCK2;CENPQ;SPC24;MAD2L1;SPC25","","R-HSA-2468293;R-HSA-2466068;R-HSA-2484822;R-HSA-2467794;R-HSA-1638803;R-HSA-2468287;R-HSA-1638821" R-HSA-2467813,"Separation of Sister Chromatids",50,195,0.01328971580453895,1.1102230246251565E-16,4.3298697960381105E-15,7,8,6.171887054466903E-4,9606,Homo sapiens,"ERCC6L;ZWILCH;CDCA5;CDCA8;CASC5;BUB1B;CENPA;AURKB;SKA1;CDC20;TUBA1C;TUBB6;TUBA1B;DSN1;PTTG1;TUBB3;NUF2;KNTC1;BUB3;SPDL1;BUB1;CENPU;UBE2C;PLK1;TUBB4B;NDC80;ZWINT;SGO1;CENPE;SGO2;CENPF;KIF18A;ESPL1;CENPI;INCENP;UBE2S;CENPK;CENPL;CENPM;BIRC5;CENPN;KIF2C;CENPO;DOCK2;CENPQ;SPC24;MAD2L1;SPC25","","R-HSA-174144;R-HSA-2467798;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-2467775;R-HSA-174121" R-HSA-68877,"Mitotic Prometaphase",60,211,0.014380154024398555,1.1102230246251565E-16,4.3298697960381105E-15,17,20,0.0015429717636167258,9606,Homo sapiens,"ERCC6L;ZWILCH;CASC5;BUB1B;SMC4;CDC20;TUBA1C;TUBB6;TUBA1B;TUBB3;NUF2;KNTC1;NEK2;SPDL1;TUBB;HAUS5;SGO1;SGO2;INCENP;BIRC5;KIF2C;DOCK2;CDCA5;NCAPG;CDCA8;CENPA;NCAPH;SKA1;AURKB;CCNB2;DSN1;CCNB1;HAUS8;CEP72;BUB3;BUB1;PLK4;CENPU;CEP152;PLK1;TUBB4B;NDC80;ZWINT;CENPE;KIF18A;CENPF;CENPI;CENPJ;CENPK;CDK1;CENPL;CENPM;CENPN;CENPO;CENPQ;SPC24;SPC25;MAD2L1","","R-HSA-2514854;R-HSA-2468293;R-HSA-9648114;R-HSA-9648017;R-HSA-375302;R-HSA-156682;R-HSA-1638803;R-HSA-2466068;R-HSA-2529015;R-HSA-2484822;R-HSA-2520883;R-HSA-2467794;R-HSA-380316;R-HSA-380508;R-HSA-2468287;R-HSA-2529020;R-HSA-1638821" R-HSA-69278,"Cell Cycle, Mitotic",156,596,0.04061882368977033,1.1102230246251565E-16,4.3298697960381105E-15,291,350,0.0270020058632927,9606,Homo sapiens,"ERCC6L;ZWILCH;CASC5;BUB1B;SMC4;CDC20;TUBB6;PTTG1;TUBB3;HIST1H2AE;HIST1H2AD;KNTC1;NEK2;FBXO5;GTSE1;TMPO;LIG1;HIST1H2AK;ESCO2;CDC25C;CDC25A;SGO1;SGO2;CCNE2;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST1H3J;CDCA5;NCAPG;CDCA8;HMMR;PKMYT1;NCAPH;SKA1;CCNB2;CCNB1;DSN1;ORC6;ORC1;CEP72;HIST1H3B;PLK4;CDT1;UBE2C;HIST1H4L;NCAPH2;PLK1;CDC7;H2BFS;CDC6;NDC80;ZWINT;TPX2;POLA2;KIF18A;HIST1H4B;UBE2S;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;CDKN1C;TOP2A;FEN1;MCM7;MCM8;NCAPG2;MCM10;CKS1B;LMNB1;TUBA1C;TUBA1B;NUF2;MYBL2;TK1;SPDL1;RFC3;RFC4;H2AFZ;RFC2;TUBB;H2AFX;HIST2H2BB;KIF23;HAUS5;MASTL;CCNA2;RBL1;DBF4;ESPL1;INCENP;BIRC5;KIF2C;MCM5;DOCK2;MCM2;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;PRIM1;HIST1H2BL;HIST1H2BK;LIN9;TYMS;CENPA;AURKB;AURKA;HIST2H4A;CDC45;HAUS8;POLD1;E2F1;BUB3;BUB1;CDKN2D;GINS1;CENPU;GINS2;RRM2;CEP152;GINS3;GINS4;TUBB4B;CENPE;CENPF;CENPI;POLE2;CENPJ;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;SPC24;SPC25;MAD2L1","","R-HSA-375302;R-HSA-156673;R-HSA-156678;R-HSA-8961678;R-HSA-69127;R-HSA-156682;R-HSA-8961665;R-HSA-174088;R-HSA-187916;R-HSA-8961671;R-HSA-8961688;R-HSA-174097;R-HSA-69140;R-HSA-69142;R-HSA-156699;R-HSA-69144;R-HSA-174104;R-HSA-174105;R-HSA-187934;R-HSA-174110;R-HSA-69152;R-HSA-380455;R-HSA-187937;R-HSA-174119;R-HSA-9018017;R-HSA-174122;R-HSA-174120;R-HSA-3000327;R-HSA-174121;R-HSA-8961699;R-HSA-187948;R-HSA-187949;R-HSA-156723;R-HSA-69173;R-HSA-187959;R-HSA-174132;R-HSA-174139;R-HSA-170044;R-HSA-2245218;R-HSA-174144;R-HSA-170055;R-HSA-69191;R-HSA-4088441;R-HSA-4088439;R-HSA-69195;R-HSA-170057;R-HSA-174159;R-HSA-69199;R-HSA-174157;R-HSA-170070;R-HSA-174164;R-HSA-174171;R-HSA-380508;R-HSA-170072;R-HSA-8942803;R-HSA-174174;R-HSA-170076;R-HSA-2430533;R-HSA-2430535;R-HSA-170087;R-HSA-170084;R-HSA-69227;R-HSA-170088;R-HSA-141423;R-HSA-174195;R-HSA-9624800;R-HSA-2484822;R-HSA-141429;R-HSA-174202;R-HSA-174203;R-HSA-69754;R-HSA-8942836;R-HSA-69756;R-HSA-141437;R-HSA-187520;R-HSA-174209;R-HSA-170116;R-HSA-8942607;R-HSA-8962050;R-HSA-170126;R-HSA-174227;R-HSA-170131;R-HSA-174224;R-HSA-174235;R-HSA-8848414;R-HSA-2473151;R-HSA-8854044;R-HSA-187545;R-HSA-174238;R-HSA-2995376;R-HSA-8854041;R-HSA-187552;R-HSA-170149;R-HSA-174251;R-HSA-170153;R-HSA-170158;R-HSA-174255;R-HSA-5244669;R-HSA-170159;R-HSA-170156;R-HSA-69299;R-HSA-170161;R-HSA-8848436;R-HSA-187574;R-HSA-4086410;R-HSA-187575;R-HSA-8932400;R-HSA-163010;R-HSA-174273;R-HSA-5195402;R-HSA-5229194;R-HSA-2993898;R-HSA-179410;R-HSA-157906;R-HSA-2529015;R-HSA-2529020;R-HSA-179417;R-HSA-8961619;R-HSA-2172666;R-HSA-8961620;R-HSA-179421;R-HSA-2468039;R-HSA-2473152;R-HSA-4088024;R-HSA-8961632;R-HSA-2468041;R-HSA-8961636;R-HSA-8961651;R-HSA-9648017;R-HSA-2172194;R-HSA-8964492;R-HSA-8852354;R-HSA-8961934;R-HSA-8961920;R-HSA-8964482;R-HSA-2294574;R-HSA-8852362;R-HSA-2990882;R-HSA-2984226;R-HSA-8961946;R-HSA-2520883;R-HSA-2294580;R-HSA-8853405;R-HSA-8964498;R-HSA-2294590;R-HSA-188191;R-HSA-8961961;R-HSA-8964525;R-HSA-2172678;R-HSA-8961952;R-HSA-8964513;R-HSA-9686969;R-HSA-8853419;R-HSA-176942;R-HSA-2168079;R-HSA-68913;R-HSA-2984220;R-HSA-2466068;R-HSA-8853429;R-HSA-2429719;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-2301205;R-HSA-8961982;R-HSA-2172183;R-HSA-68919;R-HSA-68918;R-HSA-8964531;R-HSA-8961972;R-HSA-176956;R-HSA-182594;R-HSA-1362261;R-HSA-8853444;R-HSA-1362270;R-HSA-68940;R-HSA-8964550;R-HSA-8961991;R-HSA-68944;R-HSA-68947;R-HSA-68946;R-HSA-68948;R-HSA-9686980;R-HSA-68950;R-HSA-8964561;R-HSA-68954;R-HSA-4088162;R-HSA-1363274;R-HSA-8964567;R-HSA-9648114;R-HSA-68960;R-HSA-113504;R-HSA-162657;R-HSA-8964588;R-HSA-2314566;R-HSA-1363314;R-HSA-4088152;R-HSA-8978926;R-HSA-2294600;R-HSA-8964580;R-HSA-380278;R-HSA-1363303;R-HSA-380272;R-HSA-4088134;R-HSA-1363311;R-HSA-1226094;R-HSA-4088130;R-HSA-1226095;R-HSA-380283;R-HSA-1363306;R-HSA-8853496;R-HSA-8962039;R-HSA-2514854;R-HSA-380294;R-HSA-3002798;R-HSA-1227671;R-HSA-1638803;R-HSA-380303;R-HSA-69005;R-HSA-69006;R-HSA-380311;R-HSA-1363328;R-HSA-69015;R-HSA-3002811;R-HSA-1363331;R-HSA-380316;R-HSA-69016;R-HSA-2468287;R-HSA-2467775;R-HSA-69019;R-HSA-8961840;R-HSA-188345;R-HSA-69562;R-HSA-1638821;R-HSA-188350;R-HSA-69053;R-HSA-8961846;R-HSA-8852280;R-HSA-2288097;R-HSA-2467809;R-HSA-2467811;R-HSA-69063;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-69068;R-HSA-4088305;R-HSA-8961863;R-HSA-8941895;R-HSA-9668419;R-HSA-188371;R-HSA-3000319;R-HSA-8941915;R-HSA-69074;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-8852317;R-HSA-8961874;R-HSA-3000310;R-HSA-2574840;R-HSA-188386;R-HSA-2468293;R-HSA-8852324;R-HSA-188390;R-HSA-174054;R-HSA-113638;R-HSA-174058;R-HSA-8961888;R-HSA-113643;R-HSA-174057;R-HSA-8852331;R-HSA-2214351;R-HSA-8961895;R-HSA-8961915;R-HSA-2467798;R-HSA-8964475;R-HSA-174070;R-HSA-8852337;R-HSA-2467794;R-HSA-169461;R-HSA-8852351;R-HSA-2562526;R-HSA-8964465;R-HSA-8961907;R-HSA-174079;R-HSA-69116;R-HSA-169468;R-HSA-8964471" R-HSA-5693538,"Homology Directed Repair",37,130,0.0088598105363593,1.1102230246251565E-16,4.3298697960381105E-15,41,50,0.0038574294090418146,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;FEN1;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;BRCA2;HIST2H4A;RAD51AP1;BRIP1;EME1;EXO1;POLD1;CLSPN;GEN1;POLQ;RFC3;RFC4;RFC2;HIST1H4L;XRCC2;XRCC3;H2AFX;HIST2H2BB;H2BFS;CCNA2;HIST1H4B;RAD51;POLE2;CDK2;HIST1H2BF;TIMELESS;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5684887;R-HSA-5684052;R-HSA-5693589;R-HSA-5684882;R-HSA-5685011;R-HSA-5686483;R-HSA-5693584;R-HSA-5686430;R-HSA-5685341;R-HSA-5687640;R-HSA-5693593;R-HSA-5685318;R-HSA-5685319;R-HSA-5686469;R-HSA-5684096;R-HSA-5686657;R-HSA-5685838;R-HSA-5693580;R-HSA-5684108;R-HSA-5686410;R-HSA-5684875;R-HSA-5686475;R-HSA-5693620;R-HSA-5686642;R-HSA-5687664;R-HSA-5684081;R-HSA-5686398;R-HSA-5693564;R-HSA-5687484;R-HSA-5685242;R-HSA-5693561;R-HSA-5693542;R-HSA-5684071;R-HSA-5685156;R-HSA-5687653;R-HSA-5693539;R-HSA-5685985;R-HSA-5685230;R-HSA-5685994;R-HSA-5686440;R-HSA-5693608" R-HSA-1640170,"Cell Cycle",175,734,0.05002385333605943,1.1102230246251565E-16,4.3298697960381105E-15,356,449,0.034639716093195494,9606,Homo sapiens,"ERCC6L;ZWILCH;HJURP;CASC5;BUB1B;SMC4;CDC20;TUBB6;PTTG1;TUBB3;HIST1H2AE;HIST1H2AD;KNTC1;OIP5;NEK2;STRA13;FBXO5;GTSE1;TMPO;LIG1;HIST1H2AK;ESCO2;CDC25C;CDC25A;SGO1;SGO2;CCNE2;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;BLM;HIST1H3J;CDCA5;NCAPG;CDCA8;HMMR;PKMYT1;NCAPH;SKA1;CCNB2;CCNB1;BRIP1;DSN1;ORC6;ORC1;CEP72;CLSPN;HIST1H3B;PLK4;CDT1;UBE2C;HIST1H4L;NCAPH2;PLK1;CDC7;H2BFS;CDC6;NDC80;ZWINT;TPX2;POLA2;KIF18A;HIST1H4B;UBE2S;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;WRAP53;CDKN1C;TOP2A;FEN1;SYCP2;MCM7;MCM8;NCAPG2;MCM10;BRCA1;CHTF18;BRCA2;CKS1B;LMNB1;TUBA1C;TUBA1B;EXO1;NUF2;MYBL2;TK1;SPDL1;RFC3;RFC4;H2AFZ;RFC2;TUBB;H2AFX;HIST2H2BB;KIF23;HAUS5;MASTL;CCNA2;RBL1;DBF4;ESPL1;INCENP;DMC1;BIRC5;KIF2C;MCM5;DOCK2;MCM2;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;PRIM1;HIST1H2BL;HIST1H2BK;LIN9;TYMS;CENPA;AURKB;AURKA;PSMC3IP;HIST2H4A;CDC45;HAUS8;POLD1;E2F1;RAD54L;BUB3;BUB1;CDKN2D;GINS1;CENPU;GINS2;RRM2;CENPW;CEP152;GINS3;GINS4;MND1;TUBB4B;CENPE;CENPF;RAD51;MIS18A;CENPI;POLE2;CENPJ;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;SPC24;SPC25;MAD2L1","","R-HSA-375302;R-HSA-156673;R-HSA-156678;R-HSA-8961678;R-HSA-69127;R-HSA-156682;R-HSA-912389;R-HSA-8961665;R-HSA-174088;R-HSA-187916;R-HSA-8961671;R-HSA-8961688;R-HSA-174097;R-HSA-912408;R-HSA-69140;R-HSA-69142;R-HSA-156699;R-HSA-69144;R-HSA-174104;R-HSA-174105;R-HSA-187934;R-HSA-174110;R-HSA-912429;R-HSA-75809;R-HSA-69152;R-HSA-380455;R-HSA-187937;R-HSA-174119;R-HSA-9018017;R-HSA-174122;R-HSA-174120;R-HSA-3000327;R-HSA-174121;R-HSA-8961699;R-HSA-187948;R-HSA-187949;R-HSA-156723;R-HSA-69173;R-HSA-187959;R-HSA-174132;R-HSA-174139;R-HSA-176702;R-HSA-176700;R-HSA-170044;R-HSA-2245218;R-HSA-5683735;R-HSA-174144;R-HSA-170055;R-HSA-606287;R-HSA-69191;R-HSA-912458;R-HSA-4088441;R-HSA-4088439;R-HSA-69195;R-HSA-170057;R-HSA-174159;R-HSA-69199;R-HSA-912450;R-HSA-174157;R-HSA-170070;R-HSA-174164;R-HSA-606289;R-HSA-174171;R-HSA-380508;R-HSA-170072;R-HSA-8942803;R-HSA-912470;R-HSA-174174;R-HSA-912467;R-HSA-170076;R-HSA-2430533;R-HSA-2430535;R-HSA-141409;R-HSA-170087;R-HSA-170084;R-HSA-69227;R-HSA-170088;R-HSA-141422;R-HSA-141423;R-HSA-174195;R-HSA-9624800;R-HSA-2484822;R-HSA-912505;R-HSA-141431;R-HSA-141429;R-HSA-174202;R-HSA-174203;R-HSA-912503;R-HSA-69754;R-HSA-8942836;R-HSA-912496;R-HSA-141439;R-HSA-69756;R-HSA-606326;R-HSA-141437;R-HSA-187520;R-HSA-174209;R-HSA-606349;R-HSA-170116;R-HSA-8942607;R-HSA-8962050;R-HSA-176264;R-HSA-170126;R-HSA-174227;R-HSA-170131;R-HSA-174224;R-HSA-9670149;R-HSA-174235;R-HSA-8848414;R-HSA-2473151;R-HSA-8854044;R-HSA-187545;R-HSA-174238;R-HSA-2995376;R-HSA-8854041;R-HSA-187552;R-HSA-170149;R-HSA-176298;R-HSA-174251;R-HSA-170153;R-HSA-170158;R-HSA-174255;R-HSA-5244669;R-HSA-170159;R-HSA-170156;R-HSA-69299;R-HSA-170161;R-HSA-8848436;R-HSA-187574;R-HSA-4086410;R-HSA-187575;R-HSA-8932400;R-HSA-176318;R-HSA-163010;R-HSA-174273;R-HSA-5195402;R-HSA-5229194;R-HSA-2993898;R-HSA-181450;R-HSA-179410;R-HSA-157906;R-HSA-2529015;R-HSA-2529020;R-HSA-179417;R-HSA-8961619;R-HSA-2172666;R-HSA-8961620;R-HSA-179421;R-HSA-2468039;R-HSA-2473152;R-HSA-4088024;R-HSA-8961632;R-HSA-2468041;R-HSA-8961636;R-HSA-8961651;R-HSA-1214188;R-HSA-69891;R-HSA-9648017;R-HSA-2172194;R-HSA-75010;R-HSA-8964492;R-HSA-8852354;R-HSA-8961934;R-HSA-8961920;R-HSA-75016;R-HSA-8964482;R-HSA-164616;R-HSA-164617;R-HSA-2294574;R-HSA-8852362;R-HSA-164620;R-HSA-2990882;R-HSA-2984226;R-HSA-163090;R-HSA-8961946;R-HSA-2520883;R-HSA-2294580;R-HSA-163099;R-HSA-8853405;R-HSA-163096;R-HSA-8964498;R-HSA-2294590;R-HSA-188191;R-HSA-8961961;R-HSA-8964525;R-HSA-2172678;R-HSA-8961952;R-HSA-8964513;R-HSA-9686969;R-HSA-8853419;R-HSA-176942;R-HSA-2168079;R-HSA-68913;R-HSA-2984220;R-HSA-2466068;R-HSA-8853429;R-HSA-2429719;R-HSA-163120;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-2301205;R-HSA-8961982;R-HSA-2172183;R-HSA-68919;R-HSA-68918;R-HSA-8964531;R-HSA-8961972;R-HSA-176956;R-HSA-182594;R-HSA-1362261;R-HSA-8853444;R-HSA-9670101;R-HSA-1362270;R-HSA-68940;R-HSA-8964550;R-HSA-8961991;R-HSA-68944;R-HSA-68947;R-HSA-68946;R-HSA-68948;R-HSA-9686980;R-HSA-68950;R-HSA-174427;R-HSA-8964561;R-HSA-68954;R-HSA-174425;R-HSA-4088162;R-HSA-1363274;R-HSA-8964567;R-HSA-9648114;R-HSA-68960;R-HSA-113504;R-HSA-162657;R-HSA-174438;R-HSA-8964588;R-HSA-174439;R-HSA-2314566;R-HSA-1363314;R-HSA-4088152;R-HSA-9668597;R-HSA-8978926;R-HSA-9686521;R-HSA-2294600;R-HSA-174441;R-HSA-174446;R-HSA-8964580;R-HSA-174447;R-HSA-174444;R-HSA-174445;R-HSA-9670114;R-HSA-174451;R-HSA-174448;R-HSA-380278;R-HSA-1363303;R-HSA-380272;R-HSA-174452;R-HSA-4088134;R-HSA-174456;R-HSA-1363311;R-HSA-1226094;R-HSA-4088130;R-HSA-1226095;R-HSA-380283;R-HSA-1363306;R-HSA-8853496;R-HSA-8962039;R-HSA-2514854;R-HSA-6799332;R-HSA-380294;R-HSA-3002798;R-HSA-1227671;R-HSA-1638803;R-HSA-380303;R-HSA-69005;R-HSA-69006;R-HSA-380311;R-HSA-1363328;R-HSA-69015;R-HSA-3002811;R-HSA-1363331;R-HSA-380316;R-HSA-69016;R-HSA-2468287;R-HSA-2467775;R-HSA-69019;R-HSA-9668902;R-HSA-8961840;R-HSA-9668904;R-HSA-188345;R-HSA-69562;R-HSA-1638821;R-HSA-188350;R-HSA-69053;R-HSA-8961846;R-HSA-9007926;R-HSA-8852280;R-HSA-2288097;R-HSA-2467809;R-HSA-2467811;R-HSA-69063;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-69068;R-HSA-4088305;R-HSA-8961863;R-HSA-8941895;R-HSA-9668419;R-HSA-188371;R-HSA-3000319;R-HSA-8941915;R-HSA-69074;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-8852317;R-HSA-8961874;R-HSA-3000310;R-HSA-2574840;R-HSA-69598;R-HSA-188386;R-HSA-2468293;R-HSA-69600;R-HSA-8852324;R-HSA-188390;R-HSA-174054;R-HSA-69604;R-HSA-113638;R-HSA-176101;R-HSA-174058;R-HSA-8961888;R-HSA-69608;R-HSA-113643;R-HSA-9029987;R-HSA-174057;R-HSA-8852331;R-HSA-2214351;R-HSA-8961895;R-HSA-8961915;R-HSA-2467798;R-HSA-8964475;R-HSA-174070;R-HSA-8852337;R-HSA-2467794;R-HSA-169461;R-HSA-8852351;R-HSA-2562526;R-HSA-8964465;R-HSA-8961907;R-HSA-174079;R-HSA-69116;R-HSA-169468;R-HSA-8964471" R-HSA-69481,"G2/M Checkpoints",41,154,0.010495467866148708,1.1102230246251565E-16,4.3298697960381105E-15,17,24,0.001851566116340071,9606,Homo sapiens,"MCM7;MCM8;MCM10;BRCA1;EXO1;GTSE1;RFC3;RFC4;RFC2;H2AFX;HIST2H2BB;CDC25C;CDC25A;DBF4;HIST1H2BF;HIST1H2BE;MCM5;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;MCM2;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;PKMYT1;HIST2H4A;CCNB2;BRIP1;CCNB1;ORC6;CDC45;ORC1;CLSPN;HIST1H4L;CDC7;H2BFS;CDC6;HIST1H4B;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E","","R-HSA-75809;R-HSA-5683735;R-HSA-69891;R-HSA-6799332;R-HSA-75010;R-HSA-170055;R-HSA-8852354;R-HSA-69604;R-HSA-176101;R-HSA-176298;R-HSA-75016;R-HSA-9029987;R-HSA-176264;R-HSA-170070;R-HSA-8852337;R-HSA-8852351;R-HSA-176318" R-HSA-68886,"M Phase",88,416,0.028351393716349756,1.1102230246251565E-16,4.3298697960381105E-15,55,91,0.007020521524456103,9606,Homo sapiens,"ERCC6L;ZWILCH;CASC5;BUB1B;SMC4;CDC20;TUBB6;PTTG1;TUBB3;HIST1H2AE;HIST1H2AD;KNTC1;NEK2;FBXO5;TMPO;HIST1H2AK;SGO1;SGO2;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST1H3J;CDCA5;NCAPG;CDCA8;NCAPH;SKA1;CCNB2;CCNB1;DSN1;CEP72;HIST1H3B;PLK4;UBE2C;HIST1H4L;NCAPH2;PLK1;H2BFS;NDC80;ZWINT;KIF18A;HIST1H4B;UBE2S;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;NCAPG2;LMNB1;TUBA1C;TUBA1B;NUF2;SPDL1;H2AFZ;TUBB;H2AFX;HIST2H2BB;KIF23;HAUS5;MASTL;ESPL1;INCENP;BIRC5;KIF2C;DOCK2;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;CENPA;AURKB;HIST2H4A;HAUS8;BUB3;BUB1;CENPU;CEP152;TUBB4B;CENPE;CENPF;CENPI;CENPJ;CENPK;CENPL;CENPM;CENPN;CENPO;CENPQ;SPC24;SPC25;MAD2L1","","R-HSA-2514854;R-HSA-9648017;R-HSA-375302;R-HSA-2172194;R-HSA-156673;R-HSA-156682;R-HSA-1638803;R-HSA-2294574;R-HSA-2990882;R-HSA-2984226;R-HSA-2520883;R-HSA-2294580;R-HSA-380316;R-HSA-2468287;R-HSA-2467775;R-HSA-2294590;R-HSA-2995376;R-HSA-2172678;R-HSA-174121;R-HSA-5244669;R-HSA-2168079;R-HSA-2984220;R-HSA-2466068;R-HSA-156723;R-HSA-2429719;R-HSA-2301205;R-HSA-2172183;R-HSA-1638821;R-HSA-2245218;R-HSA-163010;R-HSA-174144;R-HSA-2288097;R-HSA-2467809;R-HSA-5195402;R-HSA-5229194;R-HSA-2467811;R-HSA-2993898;R-HSA-9668419;R-HSA-2529015;R-HSA-380508;R-HSA-2529020;R-HSA-2172666;R-HSA-2468293;R-HSA-2430533;R-HSA-9648114;R-HSA-2430535;R-HSA-2314566;R-HSA-2294600;R-HSA-2214351;R-HSA-9624800;R-HSA-2484822;R-HSA-380278;R-HSA-2467798;R-HSA-2467794;R-HSA-174202" R-HSA-9648025,"EML4 and NUDC in mitotic spindle formation",45,121,0.00824643903768827,1.1102230246251565E-16,4.3298697960381105E-15,3,5,3.8574294090418145E-4,9606,Homo sapiens,"ERCC6L;ZWILCH;CDCA8;CASC5;BUB1B;CENPA;AURKB;SKA1;CDC20;TUBA1C;TUBB6;TUBA1B;DSN1;TUBB3;NUF2;KNTC1;BUB3;SPDL1;BUB1;CENPU;PLK1;TUBB4B;NDC80;ZWINT;SGO1;CENPE;SGO2;CENPF;KIF18A;CENPI;INCENP;CENPK;CENPL;CENPM;BIRC5;CENPN;KIF2C;CENPO;DOCK2;CENPQ;SPC24;MAD2L1;SPC25","","R-HSA-9648114;R-HSA-9648017;R-HSA-156682" R-HSA-69620,"Cell Cycle Checkpoints",83,280,0.019082668847543106,1.1102230246251565E-16,4.3298697960381105E-15,29,56,0.004320320938126832,9606,Homo sapiens,"ERCC6L;MCM7;ZWILCH;MCM8;CASC5;BUB1B;MCM10;BRCA1;CDC20;EXO1;NUF2;KNTC1;SPDL1;GTSE1;RFC3;RFC4;RFC2;H2AFX;HIST2H2BB;CDC25C;CDC25A;SGO1;CCNA2;SGO2;DBF4;CCNE2;INCENP;HIST1H2BF;BIRC5;HIST1H2BE;MCM5;KIF2C;HIST1H2BG;DOCK2;HIST1H2BB;HIST1H2BD;HIST1H2BC;MCM2;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;CDCA8;PKMYT1;CENPA;SKA1;AURKB;HIST2H4A;CCNB2;DSN1;BRIP1;CCNB1;ORC6;CDC45;ORC1;BUB3;CLSPN;BUB1;CENPU;UBE2C;HIST1H4L;PLK1;CDC7;H2BFS;CDC6;NDC80;ZWINT;CENPE;KIF18A;CENPF;HIST1H4B;UBE2S;CENPI;CDK2;CENPK;CDK1;CENPL;CENPM;HIST1H4H;CENPN;CENPO;HIST1H4C;CENPQ;HIST1H4D;SPC24;HIST1H4E;SPC25;MAD2L1","","R-HSA-5683735;R-HSA-69891;R-HSA-6799332;R-HSA-75010;R-HSA-170055;R-HSA-8852354;R-HSA-75016;R-HSA-176264;R-HSA-170070;R-HSA-187934;R-HSA-69598;R-HSA-75809;R-HSA-69600;R-HSA-141409;R-HSA-69604;R-HSA-176101;R-HSA-176298;R-HSA-69608;R-HSA-9029987;R-HSA-141422;R-HSA-141423;R-HSA-141431;R-HSA-8852337;R-HSA-141429;R-HSA-8852351;R-HSA-69562;R-HSA-176318;R-HSA-141439;R-HSA-141437" R-HSA-2555396,"Mitotic Metaphase and Anaphase",56,250,0.017038097185306345,1.1102230246251565E-16,4.3298697960381105E-15,11,33,0.0025459034099675976,9606,Homo sapiens,"ERCC6L;ZWILCH;CASC5;BUB1B;LMNB1;CDC20;TUBA1C;TUBB6;TUBA1B;PTTG1;TUBB3;NUF2;KNTC1;SPDL1;FBXO5;TMPO;SGO1;SGO2;ESPL1;INCENP;BIRC5;KIF2C;DOCK2;CDCA5;CDCA8;CENPA;SKA1;AURKB;CCNB2;DSN1;CCNB1;BUB3;BUB1;CENPU;UBE2C;PLK1;TUBB4B;NDC80;ZWINT;CENPE;KIF18A;CENPF;UBE2S;CENPI;CENPK;CDK1;CENPL;CENPM;CENPN;CENPO;CENPQ;SPC24;SPC25;MAD2L1","","R-HSA-163010;R-HSA-9668419;R-HSA-174144;R-HSA-9624800;R-HSA-2467798;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-2467775;R-HSA-174121;R-HSA-2995376" R-HSA-68882,"Mitotic Anaphase",55,249,0.01696994479656512,1.1102230246251565E-16,4.3298697960381105E-15,10,32,0.002468754821786761,9606,Homo sapiens,"ERCC6L;ZWILCH;CASC5;BUB1B;LMNB1;CDC20;TUBA1C;TUBB6;TUBA1B;PTTG1;TUBB3;NUF2;KNTC1;SPDL1;TMPO;SGO1;SGO2;ESPL1;INCENP;BIRC5;KIF2C;DOCK2;CDCA5;CDCA8;CENPA;SKA1;AURKB;CCNB2;DSN1;CCNB1;BUB3;BUB1;CENPU;UBE2C;PLK1;TUBB4B;NDC80;ZWINT;CENPE;KIF18A;CENPF;UBE2S;CENPI;CENPK;CDK1;CENPL;CENPM;CENPN;CENPO;CENPQ;SPC24;SPC25;MAD2L1","","R-HSA-9668419;R-HSA-174144;R-HSA-9624800;R-HSA-2467798;R-HSA-2467809;R-HSA-2467811;R-HSA-174202;R-HSA-2467775;R-HSA-174121;R-HSA-2995376" R-HSA-194315,"Signaling by Rho GTPases",76,457,0.03114564165474,1.1102230246251565E-16,4.3298697960381105E-15,23,117,0.009026384817157847,9606,Homo sapiens,"ARHGAP11A;ERCC6L;ZWILCH;KIF14;CASC5;BUB1B;CDC20;TUBA1C;TUBB6;TUBA1B;TUBB3;NUF2;HIST1H2AE;HIST1H2AD;KNTC1;SPDL1;H2AFZ;HIST1H2AK;H2AFX;HIST2H2BB;CDC25C;SGO1;SGO2;DEPDC1B;INCENP;ARHGEF3;HIST1H2BF;BIRC5;HIST1H2BE;KIF2C;HIST1H2BG;DOCK2;HIST1H2BB;SCG2;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;CDCA8;ARHGAP18;IQGAP3;CENPA;SKA1;AURKB;HIST2H4A;DSN1;ARHGAP20;RACGAP1;BUB3;ECT2;HIST1H3B;BUB1;CENPU;HIST1H4L;PLK1;ARHGAP28;NEB;H2BFS;TUBB4B;NDC80;ZWINT;CENPE;KIF18A;CENPF;DIAPH3;HIST1H4B;PRC1;CENPI;CENPK;CENPL;CENPM;HIST1H4H;CENPN;CENPO;HIST1H4C;CENPQ;HIST1H4D;SPC24;HIST1H4E;SPC25;MAD2L1","","R-HSA-5626549;R-HSA-5666070;R-HSA-194913;R-HSA-5672304;R-HSA-5666160;R-HSA-5666129;R-HSA-194922;R-HSA-75016;R-HSA-5625849;R-HSA-5625848;R-HSA-5625784;R-HSA-5625883;R-HSA-5666169;R-HSA-5671737;R-HSA-5625797;R-HSA-5626469;R-HSA-5625796;R-HSA-5671749;R-HSA-5671970;R-HSA-5625870;R-HSA-5625774;R-HSA-5626507;R-HSA-5672329" R-HSA-195258,"RHO GTPase Effectors",68,326,0.022217678729639475,1.1102230246251565E-16,4.3298697960381105E-15,21,112,0.008640641876253664,9606,Homo sapiens,"ERCC6L;ZWILCH;KIF14;CASC5;BUB1B;CDC20;TUBA1C;TUBB6;TUBA1B;TUBB3;NUF2;HIST1H2AE;HIST1H2AD;KNTC1;SPDL1;H2AFZ;HIST1H2AK;H2AFX;HIST2H2BB;CDC25C;SGO1;SGO2;INCENP;HIST1H2BF;BIRC5;HIST1H2BE;KIF2C;HIST1H2BG;DOCK2;HIST1H2BB;SCG2;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;CDCA8;IQGAP3;CENPA;SKA1;AURKB;HIST2H4A;DSN1;BUB3;HIST1H3B;BUB1;CENPU;HIST1H4L;PLK1;NEB;H2BFS;TUBB4B;NDC80;ZWINT;CENPE;KIF18A;CENPF;DIAPH3;HIST1H4B;PRC1;CENPI;CENPK;CENPL;CENPM;HIST1H4H;CENPN;CENPO;HIST1H4C;CENPQ;HIST1H4D;SPC24;HIST1H4E;SPC25;MAD2L1","","R-HSA-5626549;R-HSA-5666070;R-HSA-5672304;R-HSA-5666160;R-HSA-5666129;R-HSA-75016;R-HSA-5625849;R-HSA-5625848;R-HSA-5625784;R-HSA-5625883;R-HSA-5666169;R-HSA-5671737;R-HSA-5625797;R-HSA-5626469;R-HSA-5625796;R-HSA-5671749;R-HSA-5671970;R-HSA-5625870;R-HSA-5625774;R-HSA-5626507;R-HSA-5672329" R-HSA-5663220,"RHO GTPases Activate Formins",46,149,0.010154705922442582,1.1102230246251565E-16,4.3298697960381105E-15,4,27,0.00208301188088258,9606,Homo sapiens,"ERCC6L;ZWILCH;CDCA8;CASC5;BUB1B;CENPA;AURKB;SKA1;CDC20;TUBA1C;TUBB6;TUBA1B;DSN1;TUBB3;NUF2;KNTC1;BUB3;SPDL1;BUB1;CENPU;PLK1;TUBB4B;NDC80;ZWINT;SGO1;CENPE;SGO2;CENPF;KIF18A;DIAPH3;CENPI;INCENP;CENPK;CENPL;CENPM;BIRC5;CENPN;KIF2C;CENPO;DOCK2;CENPQ;SPC24;MAD2L1;SPC25","","R-HSA-5666070;R-HSA-5666160;R-HSA-5666129;R-HSA-5666169" R-HSA-912446,"Meiotic recombination",25,58,0.003952838546991072,2.220446049250313E-16,7.993605777301127E-15,5,9,6.943372936275266E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;BRCA2;HIST2H4A;PSMC3IP;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;MND1;H2BFS;HIST1H4B;RAD51;DMC1;CDK2;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-912429;R-HSA-912458;R-HSA-912503;R-HSA-912496;R-HSA-1214188" R-HSA-69205,"G1/S-Specific Transcription",22,43,0.0029305527158726913,3.3306690738754696E-16,1.1324274851176597E-14,28,28,0.002160160469063416,9606,Homo sapiens,"CDT1;RRM2;CDC6;LIN9;TYMS;CDC25A;RBL1;CDC45;ORC1;E2F1;CDK1;TK1;FBXO5","","R-HSA-8961934;R-HSA-8961678;R-HSA-8961920;R-HSA-8961665;R-HSA-8962050;R-HSA-8961671;R-HSA-8961863;R-HSA-8961991;R-HSA-8961688;R-HSA-8961946;R-HSA-8961874;R-HSA-8961619;R-HSA-8961620;R-HSA-8961961;R-HSA-8961632;R-HSA-8961888;R-HSA-8961952;R-HSA-8961699;R-HSA-8961636;R-HSA-8961895;R-HSA-8961915;R-HSA-8961982;R-HSA-8961840;R-HSA-8961651;R-HSA-8961907;R-HSA-8961972;R-HSA-8961846;R-HSA-8962039" R-HSA-5693532,"DNA Double-Strand Break Repair",39,167,0.011381448919784638,5.551115123125783E-16,1.8318679906315083E-14,77,107,0.008254898935349484,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;FEN1;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;BRCA2;HIST2H4A;RAD51AP1;BRIP1;EME1;EXO1;POLD1;CLSPN;KPNA2;GEN1;POLQ;RFC3;RFC4;RFC2;HIST1H4L;XRCC2;XRCC3;H2AFX;EYA4;HIST2H2BB;H2BFS;CCNA2;HIST1H4B;RAD51;POLE2;CDK2;HIST1H2BF;TIMELESS;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-69891;R-HSA-5684052;R-HSA-5686483;R-HSA-5685341;R-HSA-5683930;R-HSA-5687640;R-HSA-5683801;R-HSA-5685318;R-HSA-5685319;R-HSA-5682629;R-HSA-5686469;R-HSA-5685838;R-HSA-5683405;R-HSA-5686475;R-HSA-5686900;R-HSA-5686642;R-HSA-5687664;R-HSA-5684081;R-HSA-5693566;R-HSA-5686398;R-HSA-5683967;R-HSA-5683964;R-HSA-5693564;R-HSA-5685242;R-HSA-5693561;R-HSA-5693542;R-HSA-5684071;R-HSA-5687653;R-HSA-5693539;R-HSA-5693536;R-HSA-5683425;R-HSA-5685985;R-HSA-5685230;R-HSA-5693551;R-HSA-5693549;R-HSA-5685994;R-HSA-5682967;R-HSA-5683735;R-HSA-5684887;R-HSA-5682965;R-HSA-5693589;R-HSA-5683986;R-HSA-5684882;R-HSA-5685011;R-HSA-5693584;R-HSA-5686430;R-HSA-5693599;R-HSA-5682588;R-HSA-5686685;R-HSA-5682586;R-HSA-5693593;R-HSA-5683077;R-HSA-5659781;R-HSA-5684096;R-HSA-5686657;R-HSA-5693583;R-HSA-5693580;R-HSA-5684108;R-HSA-5686410;R-HSA-5684875;R-HSA-5693620;R-HSA-5686704;R-HSA-5682992;R-HSA-5687484;R-HSA-5683384;R-HSA-5683385;R-HSA-5682598;R-HSA-5684006;R-HSA-5682983;R-HSA-5685156;R-HSA-5693602;R-HSA-5682607;R-HSA-5682863;R-HSA-5682858;R-HSA-5686440;R-HSA-5693608;R-HSA-5684008" R-HSA-2299718,"Condensation of Prophase Chromosomes",23,55,0.0037483813807673958,5.218048215738236E-15,1.6697754290362354E-13,10,10,7.714858818083629E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;NCAPG2;SMC4;HIST2H4A;CCNB1;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;NCAPH2;PLK1;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-2245218;R-HSA-2429719;R-HSA-2288097;R-HSA-2301205;R-HSA-2294580;R-HSA-2172678;R-HSA-2294600;R-HSA-2172666;R-HSA-2294574;R-HSA-2294590" R-HSA-157579,"Telomere Maintenance",31,111,0.0075649151502760175,5.440092820663267E-15,1.6864287744056128E-13,31,34,0.002623051998148434,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;FEN1;HIST1H2BO;HIST1H2BJ;HIST1H2BI;PRIM1;HIST1H2BL;HIST1H2BK;CHTF18;HIST2H4A;POLD1;HIST1H2AE;RAD54L;HIST1H2AD;RFC3;RFC4;LIG1;H2AFZ;RFC2;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;CCNA2;POLA2;HIST1H4B;CDK2;HIST1H2BF;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;WRAP53;HIST1H2BC","","R-HSA-9670101;R-HSA-181450;R-HSA-164616;R-HSA-164617;R-HSA-164620;R-HSA-163090;R-HSA-9670149;R-HSA-174427;R-HSA-163099;R-HSA-163096;R-HSA-174425;R-HSA-174438;R-HSA-174439;R-HSA-9668597;R-HSA-9686521;R-HSA-174441;R-HSA-174446;R-HSA-174447;R-HSA-174444;R-HSA-174445;R-HSA-9670114;R-HSA-174451;R-HSA-174448;R-HSA-163120;R-HSA-9668902;R-HSA-174452;R-HSA-174456;R-HSA-9668904;R-HSA-176702;R-HSA-176700;R-HSA-9007926" R-HSA-1538133,"G0 and Early G1",19,38,0.0025897907721665644,5.573319583618286E-14,1.6719958750854857E-12,26,27,0.00208301188088258,9606,Homo sapiens,"TOP2A;CCNA2;RBL1;CCNE2;CDK2;E2F1;CDK1;MYBL2;CDC6;LIN9;CDC25A","","R-HSA-1362261;R-HSA-8964492;R-HSA-1227671;R-HSA-8961934;R-HSA-8961665;R-HSA-8964482;R-HSA-1362270;R-HSA-8964550;R-HSA-8964561;R-HSA-8964498;R-HSA-8961619;R-HSA-8964567;R-HSA-8964588;R-HSA-8964525;R-HSA-1363314;R-HSA-8978926;R-HSA-8964513;R-HSA-8964580;R-HSA-1363303;R-HSA-8964475;R-HSA-8964465;R-HSA-8964531;R-HSA-188345;R-HSA-1363311;R-HSA-1363306;R-HSA-8964471" R-HSA-176187,"Activation of ATR in response to replication stress",19,39,0.00265794316090779,8.748557434046234E-14,2.5370816558734077E-12,6,9,6.943372936275266E-4,9606,Homo sapiens,"RFC3;RFC4;MCM7;RFC2;MCM8;MCM10;CDC7;CDC6;CDC25C;CDC25A;ORC6;CDC45;DBF4;ORC1;CDK2;MCM5;CLSPN;MCM2","","R-HSA-75010;R-HSA-69604;R-HSA-176101;R-HSA-176298;R-HSA-176264;R-HSA-176318" R-HSA-1500620,"Meiosis",27,92,0.006270019764192735,9.880984919163893E-14,2.667865928174251E-12,11,15,0.0011572288227125443,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;SYCP2;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;BRCA2;LMNB1;HIST2H4A;PSMC3IP;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;MND1;H2BFS;HIST1H4B;RAD51;DMC1;CDK2;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-912429;R-HSA-912505;R-HSA-912408;R-HSA-912458;R-HSA-912389;R-HSA-912503;R-HSA-912470;R-HSA-912496;R-HSA-912467;R-HSA-1214188;R-HSA-912450" R-HSA-69306,"DNA Replication",33,142,0.009677639201254005,1.1035616864774056E-13,2.8692603848412546E-12,43,47,0.0036259836444993056,9606,Homo sapiens,"FEN1;MCM7;MCM8;PRIM1;MCM10;ORC6;CDC45;ORC1;POLD1;E2F1;GINS1;CDT1;GINS2;RFC3;RFC4;LIG1;RFC2;UBE2C;GINS3;GINS4;CDC7;CDC6;CCNA2;POLA2;DBF4;CCNE2;UBE2S;POLE2;CDK2;CDK1;MCM5;MCM2","","R-HSA-68611;R-HSA-68615;R-HSA-69063;R-HSA-69127;R-HSA-69005;R-HSA-68940;R-HSA-69068;R-HSA-176973;R-HSA-69006;R-HSA-68944;R-HSA-68688;R-HSA-68947;R-HSA-68946;R-HSA-69074;R-HSA-68948;R-HSA-69140;R-HSA-69015;R-HSA-69142;R-HSA-68950;R-HSA-69144;R-HSA-69016;R-HSA-69019;R-HSA-68826;R-HSA-68954;R-HSA-68637;R-HSA-68960;R-HSA-69152;R-HSA-68712;R-HSA-176942;R-HSA-68849;R-HSA-68913;R-HSA-69299;R-HSA-68914;R-HSA-68917;R-HSA-69173;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-169461;R-HSA-69053;R-HSA-69116;R-HSA-176956;R-HSA-169468" R-HSA-9616222,"Transcriptional regulation of granulopoiesis",24,71,0.004838819600627002,1.2378986724570495E-13,3.094746681142624E-12,20,27,0.00208301188088258,9606,Homo sapiens,"HIST1H2BN;CEBPA;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;E2F1;HIST1H2AE;HIST1H2AD;HIST1H3B;IL6R;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;CDK2;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9622386;R-HSA-9616243;R-HSA-9624112;R-HSA-9616241;R-HSA-9618582;R-HSA-9616214;R-HSA-9617207;R-HSA-8865505;R-HSA-9618586;R-HSA-9622363;R-HSA-9624120;R-HSA-9622367;R-HSA-9617087;R-HSA-9634430;R-HSA-9624668;R-HSA-9634429;R-HSA-9634433;R-HSA-9634442;R-HSA-9634446;R-HSA-9634445" R-HSA-2559586,"DNA Damage/Telomere Stress Induced Senescence",24,71,0.004838819600627002,1.2378986724570495E-13,3.094746681142624E-12,4,18,0.0013886745872550533,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;LMNB1;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H1E;HIST1H1A;HIST1H1B;HIST1H1C;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;CCNA2;HIST1H4B;CCNE2;CDK2;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-3785711;R-HSA-69562;R-HSA-4647594;R-HSA-187934" R-HSA-5334118,"DNA methylation",18,36,0.0024534859946841138,2.5557334026871104E-13,6.133760166449065E-12,7,7,5.40040117265854E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;UHRF1;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5334097;R-HSA-5334160;R-HSA-5334099;R-HSA-5334179;R-HSA-5334164;R-HSA-5334151;R-HSA-5334152" R-HSA-69190,"DNA strand elongation",18,38,0.0025897907721665644,6.212808045802376E-13,1.4289458505345465E-11,15,15,0.0011572288227125443,9606,Homo sapiens,"GINS1;GINS2;FEN1;RFC3;RFC4;MCM7;LIG1;RFC2;MCM8;PRIM1;GINS3;GINS4;POLA2;CDC45;POLD1;MCM5;MCM2","","R-HSA-69152;R-HSA-69063;R-HSA-69127;R-HSA-176942;R-HSA-69068;R-HSA-69074;R-HSA-69173;R-HSA-69140;R-HSA-169461;R-HSA-69142;R-HSA-69144;R-HSA-69053;R-HSA-69116;R-HSA-176956;R-HSA-169468" R-HSA-73894,"DNA Repair",53,368,0.02508007905677094,8.707479182135103E-13,1.9156454200697226E-11,160,328,0.025304736923314305,9606,Homo sapiens,"DCLRE1B;FEN1;BRCA1;BRCA2;GMPPB;EME1;EXO1;HIST1H2AE;HIST1H2AD;STRA13;KPNA2;GEN1;RFC3;RFC4;LIG1;H2AFZ;RFC2;HIST1H2AK;H2AFX;HIST2H2BB;CCNA2;NEIL3;FANCD2;HIST1H2BF;TIMELESS;HIST1H2BE;HIST1H2BG;HIST1H2BB;DTL;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;RAD51AP1;HIST2H4A;BRIP1;POLD1;CLSPN;FANCI;POLQ;HIST1H4L;XRCC2;XRCC3;EYA4;FANCA;FANCB;H2BFS;RAD51;HIST1H4B;POLE2;UBE2T;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E","","R-HSA-6785126;R-HSA-69891;R-HSA-5684052;R-HSA-5655892;R-HSA-5656148;R-HSA-5653840;R-HSA-5651792;R-HSA-5656158;R-HSA-5685341;R-HSA-5651805;R-HSA-6786155;R-HSA-5687640;R-HSA-5683801;R-HSA-9635996;R-HSA-5685318;R-HSA-5651782;R-HSA-6786166;R-HSA-5685319;R-HSA-5685838;R-HSA-5653838;R-HSA-110363;R-HSA-5651789;R-HSA-6786171;R-HSA-110364;R-HSA-110368;R-HSA-5686900;R-HSA-110371;R-HSA-5690997;R-HSA-5686642;R-HSA-5687664;R-HSA-5684081;R-HSA-9629365;R-HSA-5693566;R-HSA-5686398;R-HSA-5693564;R-HSA-9629369;R-HSA-9629372;R-HSA-9629373;R-HSA-5693561;R-HSA-5691001;R-HSA-5693542;R-HSA-5684071;R-HSA-5687653;R-HSA-5690213;R-HSA-5693539;R-HSA-5693536;R-HSA-6785361;R-HSA-5651809;R-HSA-5693551;R-HSA-5690988;R-HSA-5693549;R-HSA-9636008;R-HSA-9629358;R-HSA-5682967;R-HSA-5683735;R-HSA-5653780;R-HSA-5682965;R-HSA-5683986;R-HSA-5685011;R-HSA-6788385;R-HSA-5358619;R-HSA-5653786;R-HSA-5651739;R-HSA-5655835;R-HSA-5651992;R-HSA-6788392;R-HSA-5653766;R-HSA-5358592;R-HSA-5358597;R-HSA-5358599;R-HSA-6785087;R-HSA-6785342;R-HSA-5653770;R-HSA-6785594;R-HSA-5651723;R-HSA-6782211;R-HSA-5682992;R-HSA-6782208;R-HSA-5651773;R-HSA-5684006;R-HSA-5682983;R-HSA-5652005;R-HSA-6782227;R-HSA-6782224;R-HSA-5684008;R-HSA-5652009;R-HSA-5656105;R-HSA-5358545;R-HSA-5686483;R-HSA-5649873;R-HSA-5683930;R-HSA-9629470;R-HSA-5649883;R-HSA-5682629;R-HSA-5686469;R-HSA-9629195;R-HSA-5683405;R-HSA-5654989;R-HSA-5654986;R-HSA-5686475;R-HSA-5654985;R-HSA-5358579;R-HSA-6785732;R-HSA-6785986;R-HSA-9629492;R-HSA-5683967;R-HSA-9629499;R-HSA-5683964;R-HSA-5653756;R-HSA-9629497;R-HSA-5653754;R-HSA-5685242;R-HSA-9629216;R-HSA-5683425;R-HSA-5685985;R-HSA-5685230;R-HSA-9629483;R-HSA-5685994;R-HSA-5684887;R-HSA-5693589;R-HSA-5684882;R-HSA-5693584;R-HSA-5686430;R-HSA-5693599;R-HSA-5682588;R-HSA-5686685;R-HSA-5655965;R-HSA-5682586;R-HSA-5693593;R-HSA-5683077;R-HSA-5659781;R-HSA-5684096;R-HSA-5686657;R-HSA-5693583;R-HSA-5693580;R-HSA-5684108;R-HSA-5686410;R-HSA-5684875;R-HSA-5652151;R-HSA-5693620;R-HSA-110307;R-HSA-110308;R-HSA-5686704;R-HSA-110311;R-HSA-5687484;R-HSA-110317;R-HSA-110316;R-HSA-5683384;R-HSA-110319;R-HSA-5683385;R-HSA-5655481;R-HSA-5682598;R-HSA-5685156;R-HSA-5693602;R-HSA-5682607;R-HSA-5682863;R-HSA-5682858;R-HSA-5655466;R-HSA-5686440;R-HSA-5693608" R-HSA-73728,"RNA Polymerase I Promoter Opening",17,34,0.002317181217201663,1.1718404024918527E-12,2.578048885482076E-11,1,2,1.5429717636167257E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-73718" R-HSA-69473,"G2/M DNA damage checkpoint",24,81,0.005520343488039256,1.9076962232134065E-12,4.0061620687481536E-11,7,12,9.257830581700355E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;HIST2H4A;BRIP1;CCNB1;EXO1;RFC3;RFC4;RFC2;HIST1H4L;H2AFX;HIST2H2BB;H2BFS;CDC25C;HIST1H4B;HIST1H2BF;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-75809;R-HSA-5683735;R-HSA-69891;R-HSA-6799332;R-HSA-170070;R-HSA-75016;R-HSA-9029987" R-HSA-5693607,"Processing of DNA double-strand break ends",25,90,0.006133714986710284,2.6086910409617303E-12,5.478251186019634E-11,14,17,0.001311525999074217,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;HIST2H4A;BRIP1;EXO1;CLSPN;RFC3;RFC4;RFC2;HIST1H4L;H2AFX;HIST2H2BB;H2BFS;CCNA2;HIST1H4B;CDK2;HIST1H2BF;TIMELESS;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5684887;R-HSA-5684052;R-HSA-5684882;R-HSA-5685011;R-HSA-5684081;R-HSA-5693542;R-HSA-5684071;R-HSA-5685156;R-HSA-5684096;R-HSA-5685985;R-HSA-5684108;R-HSA-5685994;R-HSA-5684875;R-HSA-5693608" R-HSA-69242,"S Phase",35,180,0.012267429973420568,2.8740343438471427E-12,5.7480686876942855E-11,46,54,0.00416602376176516,9606,Homo sapiens,"FEN1;MCM7;MCM8;CDCA5;PRIM1;LIN9;CKS1B;ORC6;CDC45;ORC1;POLD1;E2F1;GINS1;CDT1;GINS2;RFC3;RFC4;LIG1;RFC2;UBE2C;GINS3;GINS4;CDC6;ESCO2;CDC25A;CCNA2;POLA2;CCNE2;UBE2S;POLE2;CDK2;CDK1;MCM5;MCM2","","R-HSA-187520;R-HSA-174273;R-HSA-69063;R-HSA-69127;R-HSA-69005;R-HSA-69068;R-HSA-187916;R-HSA-69006;R-HSA-68944;R-HSA-68947;R-HSA-68946;R-HSA-69074;R-HSA-68948;R-HSA-69140;R-HSA-69015;R-HSA-174164;R-HSA-69142;R-HSA-68950;R-HSA-69144;R-HSA-8848414;R-HSA-69016;R-HSA-2473151;R-HSA-69019;R-HSA-187545;R-HSA-187934;R-HSA-174110;R-HSA-69152;R-HSA-187552;R-HSA-2468039;R-HSA-174054;R-HSA-2473152;R-HSA-176942;R-HSA-2468041;R-HSA-187948;R-HSA-187949;R-HSA-68913;R-HSA-8848436;R-HSA-187574;R-HSA-69173;R-HSA-187575;R-HSA-169461;R-HSA-188345;R-HSA-69053;R-HSA-69116;R-HSA-176956;R-HSA-169468" R-HSA-453274,"Mitotic G2-G2/M phases",38,214,0.01458461119062223,4.714451051768265E-12,9.42890210353653E-11,70,80,0.006171887054466903,9606,Homo sapiens,"HMMR;LIN9;PKMYT1;AURKB;AURKA;CCNB2;TUBA1C;TUBB6;CCNB1;TUBA1B;HAUS8;TUBB3;E2F1;CEP72;NEK2;MYBL2;GTSE1;PLK4;TUBB;CEP152;PLK1;HAUS5;TUBB4B;CDC25C;CDC25A;CCNA2;TPX2;CENPF;CENPJ;CDK2;CDK1","","R-HSA-380294;R-HSA-3002798;R-HSA-156678;R-HSA-8852354;R-HSA-170116;R-HSA-380303;R-HSA-170126;R-HSA-8852362;R-HSA-170131;R-HSA-380311;R-HSA-3002811;R-HSA-156699;R-HSA-8853405;R-HSA-8854044;R-HSA-8854041;R-HSA-380455;R-HSA-187937;R-HSA-170149;R-HSA-3000327;R-HSA-170153;R-HSA-8853419;R-HSA-170158;R-HSA-170159;R-HSA-170156;R-HSA-8853429;R-HSA-170161;R-HSA-4086410;R-HSA-187959;R-HSA-170044;R-HSA-8852280;R-HSA-8853444;R-HSA-170055;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-4088305;R-HSA-3000319;R-HSA-170070;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-170072;R-HSA-8852317;R-HSA-3000310;R-HSA-4088162;R-HSA-170076;R-HSA-2574840;R-HSA-162657;R-HSA-8852324;R-HSA-170087;R-HSA-170084;R-HSA-4088024;R-HSA-4088152;R-HSA-170088;R-HSA-8852331;R-HSA-380272;R-HSA-8852337;R-HSA-4088134;R-HSA-8852351;R-HSA-2562526;R-HSA-69754;R-HSA-4088130;R-HSA-69756;R-HSA-380283;R-HSA-8853496" R-HSA-212300,"PRC2 methylates histones and DNA",18,44,0.002998705104613917,6.7382766033574626E-12,1.280272554637918E-10,4,4,3.0859435272334514E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-212263;R-HSA-212222;R-HSA-212269;R-HSA-212252" R-HSA-156711,"Polo-like kinase mediated events",14,23,0.0015675049410481838,8.908429549592256E-12,1.6926016144225287E-10,15,15,0.0011572288227125443,9606,Homo sapiens,"CCNB2;CCNB1;CENPF;PLK1;MYBL2;LIN9;CDC25C;PKMYT1;CDC25A","","R-HSA-162657;R-HSA-156678;R-HSA-4088152;R-HSA-4088441;R-HSA-4088439;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-4088305;R-HSA-4088298;R-HSA-4088299;R-HSA-4088134;R-HSA-156699;R-HSA-4088130;R-HSA-4088162" R-HSA-427359,"SIRT1 negatively regulates rRNA expression",18,45,0.003066857493355142,9.677703083355027E-12,1.7578738464862909E-10,3,5,3.8574294090418145E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;SUV39H1;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-427527;R-HSA-427514;R-HSA-427528" R-HSA-110330,"Recognition and association of DNA glycosylase with site containing an affected purine",17,39,0.00265794316090779,9.765965813812727E-12,1.7578738464862909E-10,4,10,7.714858818083629E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9629365;R-HSA-9629195;R-HSA-9629358;R-HSA-9629373" R-HSA-1474165,"Reproduction",28,123,0.008382743815170722,1.2993273124095595E-11,2.338789162337207E-10,12,24,0.001851566116340071,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;SYCP2;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;BRCA2;LMNB1;HIST2H4A;PSMC3IP;HIST1H2AE;HIST1H2AD;HIST1H3B;OVGP1;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;MND1;H2BFS;HIST1H4B;RAD51;DMC1;CDK2;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-912429;R-HSA-912505;R-HSA-912408;R-HSA-912458;R-HSA-912389;R-HSA-1297338;R-HSA-912503;R-HSA-912470;R-HSA-912496;R-HSA-912467;R-HSA-1214188;R-HSA-912450" R-HSA-171306,"Packaging Of Telomere Ends",16,34,0.002317181217201663,1.302924435009345E-11,2.345263983016821E-10,2,2,1.5429717636167257E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-181450;R-HSA-176700" R-HSA-73884,"Base Excision Repair",25,99,0.006747086485381313,1.923605719156285E-11,3.2701297225656845E-10,28,105,0.00810060175898781,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;FEN1;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;POLD1;HIST1H2AE;HIST1H2AD;RFC3;RFC4;LIG1;H2AFZ;RFC2;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;POLE2;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5651792;R-HSA-5649873;R-HSA-5651805;R-HSA-9629470;R-HSA-5651739;R-HSA-5649883;R-HSA-9635996;R-HSA-5651782;R-HSA-9629195;R-HSA-110363;R-HSA-5651789;R-HSA-5651723;R-HSA-110364;R-HSA-110368;R-HSA-110371;R-HSA-9629492;R-HSA-9629365;R-HSA-9629499;R-HSA-9629497;R-HSA-9629369;R-HSA-5651773;R-HSA-9629372;R-HSA-9629373;R-HSA-9629216;R-HSA-5651809;R-HSA-9629483;R-HSA-9636008;R-HSA-9629358" R-HSA-68962,"Activation of the pre-replicative complex",16,36,0.0024534859946841138,2.98768787487802E-11,4.849738388656988E-10,9,9,6.943372936275266E-4,9606,Homo sapiens,"CDT1;MCM7;MCM8;PRIM1;MCM10;CDC7;CDC6;POLA2;ORC6;CDC45;DBF4;ORC1;POLE2;CDK2;MCM5;MCM2","","R-HSA-68960;R-HSA-69299;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-68954;R-HSA-68940" R-HSA-110328,"Recognition and association of DNA glycosylase with site containing an affected pyrimidine",17,42,0.0028624003271314658,3.0310864929106174E-11,4.849738388656988E-10,2,21,0.001620120351797562,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9629369;R-HSA-9629372" R-HSA-69275,"G2/M Transition",36,212,0.01444830641313978,5.816636061695135E-11,9.306617698712216E-10,68,78,0.00601758987810523,9606,Homo sapiens,"HMMR;LIN9;PKMYT1;AURKB;AURKA;CCNB2;TUBA1C;TUBB6;CCNB1;TUBA1B;HAUS8;TUBB3;CEP72;NEK2;MYBL2;GTSE1;PLK4;TUBB;CEP152;PLK1;HAUS5;TUBB4B;CDC25C;CDC25A;CCNA2;TPX2;CENPF;CENPJ;CDK2;CDK1","","R-HSA-380294;R-HSA-3002798;R-HSA-156678;R-HSA-8852354;R-HSA-170116;R-HSA-380303;R-HSA-170126;R-HSA-8852362;R-HSA-170131;R-HSA-380311;R-HSA-3002811;R-HSA-156699;R-HSA-8853405;R-HSA-8854044;R-HSA-8854041;R-HSA-380455;R-HSA-170149;R-HSA-3000327;R-HSA-170153;R-HSA-8853419;R-HSA-170158;R-HSA-170159;R-HSA-170156;R-HSA-8853429;R-HSA-170161;R-HSA-4086410;R-HSA-170044;R-HSA-8852280;R-HSA-8853444;R-HSA-170055;R-HSA-4088441;R-HSA-4088439;R-HSA-170057;R-HSA-4088309;R-HSA-4088306;R-HSA-4088307;R-HSA-8852298;R-HSA-4088305;R-HSA-3000319;R-HSA-170070;R-HSA-4088298;R-HSA-8852306;R-HSA-4088299;R-HSA-2574845;R-HSA-170072;R-HSA-8852317;R-HSA-3000310;R-HSA-4088162;R-HSA-170076;R-HSA-2574840;R-HSA-162657;R-HSA-8852324;R-HSA-170087;R-HSA-170084;R-HSA-4088024;R-HSA-4088152;R-HSA-170088;R-HSA-8852331;R-HSA-380272;R-HSA-8852337;R-HSA-4088134;R-HSA-8852351;R-HSA-2562526;R-HSA-69754;R-HSA-4088130;R-HSA-69756;R-HSA-380283;R-HSA-8853496" R-HSA-69239,"Synthesis of DNA",28,133,0.009064267702582975,7.55755458214935E-11,1.1336331873224026E-9,26,26,0.0020058632927017436,9606,Homo sapiens,"FEN1;MCM7;MCM8;PRIM1;ORC6;CDC45;ORC1;POLD1;GINS1;CDT1;GINS2;RFC3;RFC4;LIG1;RFC2;UBE2C;GINS3;GINS4;CDC6;CCNA2;POLA2;CCNE2;UBE2S;POLE2;CDK2;CDK1;MCM5;MCM2","","R-HSA-69063;R-HSA-69127;R-HSA-69005;R-HSA-69068;R-HSA-69006;R-HSA-68944;R-HSA-68947;R-HSA-68946;R-HSA-69074;R-HSA-68948;R-HSA-69140;R-HSA-69015;R-HSA-69142;R-HSA-68950;R-HSA-69144;R-HSA-69016;R-HSA-69019;R-HSA-69152;R-HSA-176942;R-HSA-68913;R-HSA-69173;R-HSA-169461;R-HSA-69053;R-HSA-69116;R-HSA-176956;R-HSA-169468" R-HSA-110331,"Cleavage of the damaged purine",17,45,0.003066857493355142,8.624534419965357E-11,1.2936801629948036E-9,4,9,6.943372936275266E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9629216;R-HSA-9629492;R-HSA-9629483;R-HSA-9629470" R-HSA-73927,"Depurination",17,46,0.0031350098820963675,1.2011491801189322E-10,1.8017237701783984E-9,8,19,0.0014658231754358896,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9629216;R-HSA-9629492;R-HSA-9629365;R-HSA-9629483;R-HSA-9629195;R-HSA-9629470;R-HSA-9629358;R-HSA-9629373" R-HSA-983189,"Kinesins",20,68,0.004634362434403326,1.499231849777516E-10,2.248847774666274E-9,10,14,0.001080080234531708,9606,Homo sapiens,"KIF23;KIF22;KIF11;TUBB4B;KIF15;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;KIF18B;RACGAP1;KIFC1;TUBB3;KIF4A;KIF2C;KIF20B","","R-HSA-984671;R-HSA-990478;R-HSA-984606;R-HSA-983259;R-HSA-990489;R-HSA-984648;R-HSA-984821;R-HSA-983266;R-HSA-984689;R-HSA-984609" R-HSA-1221632,"Meiotic synapsis",19,62,0.004225448101955974,2.1993129539765732E-10,3.0790381355672025E-9,6,6,4.6289152908501776E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;SYCP2;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;LMNB1;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-912505;R-HSA-912408;R-HSA-912389;R-HSA-912470;R-HSA-912467;R-HSA-912450" R-HSA-9670095,"Inhibition of DNA recombination at telomere",17,48,0.003271314659578818,2.275106769644708E-10,3.1851494775025913E-9,4,4,3.0859435272334514E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;RAD54L;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9670114;R-HSA-9670149;R-HSA-9670101;R-HSA-9007926" R-HSA-427389,"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression",17,48,0.003271314659578818,2.275106769644708E-10,3.1851494775025913E-9,2,4,3.0859435272334514E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-427383;R-HSA-427336" R-HSA-5625886,"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3",17,49,0.0033394670483200438,3.096208844866055E-10,4.025071498325872E-9,8,11,8.486344699891992E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5625797;R-HSA-5625796;R-HSA-5625870;R-HSA-5625774;R-HSA-5625849;R-HSA-5625848;R-HSA-5625784;R-HSA-5625883" R-HSA-68875,"Mitotic Prophase",27,135,0.009200572480065426,4.927337426963163E-10,6.405538655052112E-9,25,34,0.002623051998148434,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;NCAPG2;SMC4;LMNB1;HIST2H4A;CCNB2;CCNB1;HIST1H2AE;HIST1H2AD;HIST1H3B;TMPO;H2AFZ;HIST1H4L;HIST1H2AK;NCAPH2;PLK1;H2AFX;HIST2H2BB;H2BFS;MASTL;HIST1H4B;HIST1H2BF;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-2245218;R-HSA-2288097;R-HSA-2172194;R-HSA-5195402;R-HSA-5229194;R-HSA-2993898;R-HSA-2294574;R-HSA-2990882;R-HSA-2984226;R-HSA-2294580;R-HSA-2172666;R-HSA-2294590;R-HSA-2430533;R-HSA-2430535;R-HSA-2314566;R-HSA-2172678;R-HSA-2294600;R-HSA-5244669;R-HSA-2214351;R-HSA-2168079;R-HSA-2984220;R-HSA-2429719;R-HSA-380278;R-HSA-2301205;R-HSA-2172183" R-HSA-110329,"Cleavage of the damaged pyrimidine ",17,51,0.0034757718258024944,5.615493625654722E-10,7.300141713351138E-9,2,20,0.0015429717636167258,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9629499;R-HSA-9629497" R-HSA-73928,"Depyrimidination",17,51,0.0034757718258024944,5.615493625654722E-10,7.300141713351138E-9,4,41,0.003163092115414288,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9629499;R-HSA-9629497;R-HSA-9629369;R-HSA-9629372" R-HSA-2559582,"Senescence-Associated Secretory Phenotype (SASP)",22,91,0.00620186737545151,6.825062737192411E-10,8.872581558350134E-9,9,22,0.0016972689399783983,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;CDKN2D;H2AFZ;UBE2C;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;CCNA2;HIST1H4B;UBE2S;CDK2;HIST1H2BF;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-3788745;R-HSA-3790137;R-HSA-182594;R-HSA-3788748;R-HSA-3788705;R-HSA-3790130;R-HSA-3788725;R-HSA-3788724;R-HSA-3788708" R-HSA-2559583,"Cellular Senescence",33,200,0.013630477748245075,7.465194018507759E-10,9.31409882554135E-9,31,90,0.006943372936275266,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;LMNB1;HIST2H4A;E2F1;HIST1H2AE;HIST1H2AD;HIST1H1E;HIST1H3B;HIST1H1A;HIST1H1B;MAP2K6;HIST1H1C;CDKN2D;H2AFZ;UBE2C;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;CCNA2;HIST1H4B;CCNE2;UBE2S;CDK2;HIST1H2BF;CDK1;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;EZH2;HIST1H2BC","","R-HSA-3790137;R-HSA-182594;R-HSA-3228469;R-HSA-3790130;R-HSA-3788725;R-HSA-3240765;R-HSA-3240957;R-HSA-3788724;R-HSA-3240766;R-HSA-3229089;R-HSA-3223200;R-HSA-3785711;R-HSA-3240295;R-HSA-3788705;R-HSA-450333;R-HSA-187934;R-HSA-3788708;R-HSA-3229102;R-HSA-3240787;R-HSA-3209109;R-HSA-3238999;R-HSA-4647594;R-HSA-3788745;R-HSA-3222593;R-HSA-3788748;R-HSA-3209096;R-HSA-3240777;R-HSA-69562;R-HSA-450296;R-HSA-3240783;R-HSA-3240782" R-HSA-201722,"Formation of the beta-catenin:TCF transactivating complex",19,67,0.0045662100456621,7.761749021284459E-10,9.31409882554135E-9,11,13,0.0010029316463508718,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;TCF7;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;SCG2;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-201712;R-HSA-3299569;R-HSA-4411351;R-HSA-3322422;R-HSA-3451153;R-HSA-3364026;R-HSA-3322427;R-HSA-3322424;R-HSA-3364014;R-HSA-3451147;R-HSA-4411372" R-HSA-176974,"Unwinding of DNA",9,12,8.178286648947046E-4,7.919935041122983E-9,9.50392204934758E-8,4,4,3.0859435272334514E-4,9606,Homo sapiens,"GINS1;GINS2;CDC45;MCM7;MCM8;GINS3;GINS4;MCM5;MCM2","","R-HSA-169461;R-HSA-176942;R-HSA-176956;R-HSA-169468" R-HSA-2559580,"Oxidative Stress Induced Senescence",23,114,0.007769372316499694,8.038898768880642E-9,9.646678522656771E-8,17,40,0.0030859435272334516,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;E2F1;HIST1H2AE;HIST1H2AD;HIST1H3B;MAP2K6;CDKN2D;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;EZH2;HIST1H2BC","","R-HSA-182594;R-HSA-3240787;R-HSA-3228469;R-HSA-3238999;R-HSA-3240765;R-HSA-3240957;R-HSA-3240766;R-HSA-3229089;R-HSA-3222593;R-HSA-3223200;R-HSA-3240295;R-HSA-3240777;R-HSA-450333;R-HSA-450296;R-HSA-3240783;R-HSA-3229102;R-HSA-3240782" R-HSA-5250924,"B-WICH complex positively regulates rRNA expression",17,62,0.004225448101955974,9.751662588541876E-9,1.1701995106250251E-7,1,3,2.3144576454250888E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5250938" R-HSA-73929,"Base-Excision Repair, AP Site Formation",17,62,0.004225448101955974,9.751662588541876E-9,1.1701995106250251E-7,14,62,0.00478321246721185,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;NEIL3;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9629492;R-HSA-9629365;R-HSA-9629499;R-HSA-9629497;R-HSA-9629369;R-HSA-9629470;R-HSA-9629372;R-HSA-9629373;R-HSA-9635996;R-HSA-9629216;R-HSA-9629483;R-HSA-9629195;R-HSA-9636008;R-HSA-9629358" R-HSA-3214815,"HDACs deacetylate histones",17,63,0.004293600490697199,1.226965873346586E-8,1.3496624606812446E-7,4,4,3.0859435272334514E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;HIST1H4L;HIST1H2AH;HIST1H2AK;HIST2H2BB;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-3777129;R-HSA-3782637;R-HSA-3782655;R-HSA-3769447" R-HSA-5685942,"HDR through Homologous Recombination (HRR)",18,72,0.0049069719893682275,1.4530983749594384E-8,1.5984082124553822E-7,19,19,0.0014658231754358896,9606,Homo sapiens,"GEN1;BLM;RFC3;RFC4;RFC2;XRCC2;XRCC3;BRCA1;BRCA2;RAD51AP1;BRIP1;RAD51;EME1;EXO1;POLE2;POLD1","","R-HSA-5693620;R-HSA-5693589;R-HSA-5686483;R-HSA-5693584;R-HSA-5686398;R-HSA-5686430;R-HSA-5685341;R-HSA-5685242;R-HSA-5693593;R-HSA-5693561;R-HSA-5685318;R-HSA-5685319;R-HSA-5686469;R-HSA-5693539;R-HSA-5685838;R-HSA-5685230;R-HSA-5686410;R-HSA-5686475;R-HSA-5686440" R-HSA-73772,"RNA Polymerase I Promoter Escape",17,64,0.004361752879438424,1.5371913519857117E-8,1.6909104871842828E-7,1,2,1.5429717636167257E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-74986" R-HSA-1362277,"Transcription of E2F targets under negative control by DREAM complex",11,25,0.0017038097185306344,3.995239050702537E-8,4.394762955772791E-7,12,12,9.257830581700355E-4,9606,Homo sapiens,"TOP2A;RBL1;E2F1;CDC6;LIN9;CDC25A","","R-HSA-8964475;R-HSA-8964492;R-HSA-8964525;R-HSA-8961665;R-HSA-8964513;R-HSA-8964465;R-HSA-8964482;R-HSA-8964498;R-HSA-8964531;R-HSA-8961619;R-HSA-188345;R-HSA-8964471" R-HSA-1362300,"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1",10,20,0.0013630477748245075,5.131776303901603E-8,5.644953934291763E-7,8,8,6.171887054466903E-4,9606,Homo sapiens,"CCNA2;RBL1;E2F1;CDK1;MYBL2;LIN9","","R-HSA-8964588;R-HSA-8961934;R-HSA-8978926;R-HSA-8964513;R-HSA-8964561;R-HSA-8964580;R-HSA-8964550;R-HSA-8964567" R-HSA-1912408,"Pre-NOTCH Transcription and Translation",19,89,0.006065562597969059,6.717982548032353E-8,7.389780802835588E-7,5,28,0.002160160469063416,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;E2F1;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9604834;R-HSA-4395231;R-HSA-9604831;R-HSA-1912416;R-HSA-9604829" R-HSA-5625740,"RHO GTPases activate PKNs",18,80,0.00545219109929803,6.897980253661729E-8,7.587778279027901E-7,11,20,0.0015429717636167258,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;CDC25C;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5625797;R-HSA-5625796;R-HSA-5671749;R-HSA-75016;R-HSA-5625870;R-HSA-5625774;R-HSA-5625849;R-HSA-5625848;R-HSA-5625784;R-HSA-5625883;R-HSA-5671737" R-HSA-5693568,"Resolution of D-loop Structures through Holliday Junction Intermediates",12,36,0.0024534859946841138,1.8907978949211923E-7,1.8907978949211923E-6,9,9,6.943372936275266E-4,9606,Homo sapiens,"RAD51AP1;GEN1;BLM;BRIP1;RAD51;EME1;EXO1;XRCC2;XRCC3;BRCA1;BRCA2","","R-HSA-5686469;R-HSA-5686483;R-HSA-5693539;R-HSA-5693584;R-HSA-5686398;R-HSA-5686430;R-HSA-5686410;R-HSA-5686475;R-HSA-5686440" R-HSA-5693579,"Homologous DNA Pairing and Strand Exchange",13,44,0.002998705104613917,2.292941417847416E-7,2.292941417847416E-6,8,8,6.171887054466903E-4,9606,Homo sapiens,"RAD51AP1;BLM;RFC3;BRIP1;RFC4;RAD51;RFC2;EXO1;XRCC2;XRCC3;BRCA1;BRCA2","","R-HSA-5685318;R-HSA-5685319;R-HSA-5693620;R-HSA-5685838;R-HSA-5685230;R-HSA-5685341;R-HSA-5685242;R-HSA-5693561" R-HSA-8936459,"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function",17,78,0.00531588632181558,2.456135446138319E-7,2.456135446138319E-6,20,33,0.0025459034099675976,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-8936584;R-HSA-8936616;R-HSA-8937097;R-HSA-8937037;R-HSA-8936621;R-HSA-8936608;R-HSA-8936481;R-HSA-8936995;R-HSA-8937016;R-HSA-8937113;R-HSA-8937050;R-HSA-8935740;R-HSA-8936989;R-HSA-8937118;R-HSA-8937022;R-HSA-8935730;R-HSA-8936979;R-HSA-8935731;R-HSA-8936628;R-HSA-8936599" R-HSA-6811434,"COPI-dependent Golgi-to-ER retrograde traffic",20,107,0.007292305595311115,2.473087243881622E-7,2.473087243881622E-6,2,11,8.486344699891992E-4,9606,Homo sapiens,"KIF23;KIF22;KIF11;TUBB4B;KIF15;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;KIF18B;RACGAP1;KIFC1;TUBB3;KIF4A;KIF2C;KIF20B","","R-HSA-6811426;R-HSA-6811423" R-HSA-5693537,"Resolution of D-Loop Structures",12,37,0.002521638383425339,2.519887857266312E-7,2.519887857266312E-6,10,10,7.714858818083629E-4,9606,Homo sapiens,"RAD51AP1;GEN1;BLM;BRIP1;RAD51;EME1;EXO1;XRCC2;XRCC3;BRCA1;BRCA2","","R-HSA-5693589;R-HSA-5686469;R-HSA-5686483;R-HSA-5693539;R-HSA-5693584;R-HSA-5686398;R-HSA-5686430;R-HSA-5686410;R-HSA-5686475;R-HSA-5686440" R-HSA-69002,"DNA Replication Pre-Initiation",18,88,0.005997410209227834,2.7334068641859943E-7,2.7334068641859943E-6,17,21,0.001620120351797562,9606,Homo sapiens,"CDT1;MCM7;MCM8;PRIM1;MCM10;CDC7;CDC6;POLA2;ORC6;CDC45;DBF4;ORC1;POLE2;CDK2;E2F1;MCM5;MCM2","","R-HSA-68960;R-HSA-68611;R-HSA-68615;R-HSA-68712;R-HSA-68940;R-HSA-176973;R-HSA-68849;R-HSA-68688;R-HSA-69299;R-HSA-68914;R-HSA-68917;R-HSA-68916;R-HSA-68919;R-HSA-68918;R-HSA-68826;R-HSA-68954;R-HSA-68637" R-HSA-5250941,"Negative epigenetic regulation of rRNA expression",18,89,0.006065562597969059,3.2111418390989854E-7,3.1241647259205862E-6,6,12,9.257830581700355E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;SUV39H1;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-427527;R-HSA-427514;R-HSA-5227490;R-HSA-433672;R-HSA-427528;R-HSA-427337" R-HSA-5250913,"Positive epigenetic regulation of rRNA expression",17,80,0.00545219109929803,3.4712941399117625E-7,3.1241647259205862E-6,3,7,5.40040117265854E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-427383;R-HSA-5250938;R-HSA-427336" R-HSA-427413,"NoRC negatively regulates rRNA expression",17,80,0.00545219109929803,3.4712941399117625E-7,3.1241647259205862E-6,3,7,5.40040117265854E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5227490;R-HSA-433672;R-HSA-427337" R-HSA-5578749,"Transcriptional regulation by small RNAs",17,81,0.005520343488039256,4.1102590275787776E-7,3.6992331248209E-6,1,5,3.8574294090418145E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5578742" R-HSA-5693606,"DNA Double Strand Break Response",16,74,0.005043276766850678,6.101765225308142E-7,5.491588702777328E-6,32,44,0.0033945378799567967,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;HIST2H4A;KPNA2;HIST1H4L;H2AFX;EYA4;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5682967;R-HSA-5683735;R-HSA-69891;R-HSA-5682965;R-HSA-5683986;R-HSA-5682588;R-HSA-5683930;R-HSA-5682586;R-HSA-5683801;R-HSA-5682629;R-HSA-5683077;R-HSA-5659781;R-HSA-5693583;R-HSA-5683405;R-HSA-5682992;R-HSA-5693566;R-HSA-5683967;R-HSA-5683964;R-HSA-5683384;R-HSA-5683385;R-HSA-5682598;R-HSA-5684006;R-HSA-5682983;R-HSA-5693602;R-HSA-5693536;R-HSA-5683425;R-HSA-5682607;R-HSA-5682863;R-HSA-5693551;R-HSA-5693549;R-HSA-5682858;R-HSA-5684008" R-HSA-6791312,"TP53 Regulates Transcription of Cell Cycle Genes",15,65,0.00442990526817965,6.151741585025405E-7,5.536567426522865E-6,15,42,0.003240240703595124,9606,Homo sapiens,"CDC25C;AURKB;AURKA;CCNA2;CCNB1;RBL1;CCNE2;CENPJ;CDK2;E2F1;CDK1;E2F7;E2F8","","R-HSA-6791235;R-HSA-6803875;R-HSA-8953037;R-HSA-6801666;R-HSA-6798304;R-HSA-6798347;R-HSA-8952996;R-HSA-6798282;R-HSA-6798353;R-HSA-6802973;R-HSA-6798268;R-HSA-69562;R-HSA-6798299;R-HSA-187934;R-HSA-8953013" R-HSA-5693571,"Nonhomologous End-Joining (NHEJ)",14,57,0.003884686158249847,7.044506442621667E-7,6.340055798359501E-6,4,13,0.0010029316463508718,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H4L;HIST1H2BI;HIST1H2BL;HIST1H2BK;H2AFX;HIST2H2BB;BRCA1;H2BFS;HIST2H4A;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H2BD;HIST1H4E;HIST1H2BC","","R-HSA-5686900;R-HSA-5686704;R-HSA-5693599;R-HSA-5686685" R-HSA-5693565,"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks",15,66,0.004498057656920875,7.416823060157895E-7,6.675140754142106E-6,30,35,0.00270020058632927,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;BRCA1;HIST2H4A;HIST1H4L;H2AFX;EYA4;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5682967;R-HSA-5683735;R-HSA-69891;R-HSA-5682965;R-HSA-5683986;R-HSA-5682588;R-HSA-5683930;R-HSA-5682586;R-HSA-5683801;R-HSA-5682629;R-HSA-5683077;R-HSA-5659781;R-HSA-5693583;R-HSA-5683405;R-HSA-5682992;R-HSA-5693566;R-HSA-5683967;R-HSA-5683964;R-HSA-5683384;R-HSA-5683385;R-HSA-5682598;R-HSA-5682983;R-HSA-5693602;R-HSA-5693536;R-HSA-5683425;R-HSA-5682607;R-HSA-5682863;R-HSA-5693551;R-HSA-5693549;R-HSA-5682858" R-HSA-73854,"RNA Polymerase I Promoter Clearance",17,87,0.005929257820486608,1.0751620641569204E-6,9.676458577412284E-6,2,10,7.714858818083629E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-73718;R-HSA-74986" R-HSA-977225,"Amyloid fiber formation",17,88,0.005997410209227834,1.251788366962714E-6,1.1266095302664425E-5,1,33,0.0025459034099675976,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-977224" R-HSA-73864,"RNA Polymerase I Transcription",17,89,0.006065562597969059,1.4542426803876296E-6,1.3088184123488666E-5,2,14,0.001080080234531708,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-73718;R-HSA-74986" R-HSA-1912422,"Pre-NOTCH Expression and Processing",19,113,0.007701219927758468,2.2680837340471882E-6,2.0412753606424694E-5,5,38,0.002931646350871779,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;E2F1;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9604834;R-HSA-4395231;R-HSA-9604831;R-HSA-1912416;R-HSA-9604829" R-HSA-8854518,"AURKA Activation by TPX2",15,74,0.005043276766850678,2.949411390895662E-6,2.6292394404769937E-5,2,2,1.5429717636167257E-4,9606,Homo sapiens,"PLK4;TUBB;CEP152;PLK1;HAUS5;HMMR;TUBB4B;AURKB;AURKA;TPX2;HAUS8;CENPJ;CDK1;CEP72;NEK2","","R-HSA-8853405;R-HSA-8853419" R-HSA-5617472,"Activation of anterior HOX genes in hindbrain development during early embryogenesis",19,116,0.007905677093982145,3.286549300596242E-6,2.6292394404769937E-5,31,43,0.0033173892917759606,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;MAFB;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-5617877;R-HSA-5617492;R-HSA-5617431;R-HSA-5621010;R-HSA-5617874;R-HSA-6810159;R-HSA-6810158;R-HSA-5617887;R-HSA-5617862;R-HSA-6810161;R-HSA-5617859;R-HSA-5617676;R-HSA-5617484;R-HSA-5693644;R-HSA-5617486;R-HSA-5617672;R-HSA-5617483;R-HSA-5617867;R-HSA-5621002;R-HSA-5617866;R-HSA-5617462;R-HSA-5617650;R-HSA-5617661;R-HSA-5617471;R-HSA-5617445;R-HSA-5617452;R-HSA-5617454;R-HSA-5617641;R-HSA-6810139;R-HSA-5617896;R-HSA-5617642" R-HSA-5619507,"Activation of HOX genes during differentiation",19,116,0.007905677093982145,3.286549300596242E-6,2.6292394404769937E-5,31,43,0.0033173892917759606,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;MAFB;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-5617877;R-HSA-5617492;R-HSA-5617431;R-HSA-5621010;R-HSA-5617874;R-HSA-6810159;R-HSA-6810158;R-HSA-5617887;R-HSA-5617862;R-HSA-6810161;R-HSA-5617859;R-HSA-5617676;R-HSA-5617484;R-HSA-5693644;R-HSA-5617486;R-HSA-5617672;R-HSA-5617483;R-HSA-5617867;R-HSA-5621002;R-HSA-5617866;R-HSA-5617462;R-HSA-5617650;R-HSA-5617661;R-HSA-5617471;R-HSA-5617445;R-HSA-5617452;R-HSA-5617454;R-HSA-5617641;R-HSA-6810139;R-HSA-5617896;R-HSA-5617642" R-HSA-380320,"Recruitment of NuMA to mitotic centrosomes",17,97,0.0066107817078988615,4.4840103080590055E-6,3.5872082464472044E-5,2,2,1.5429717636167257E-4,9606,Homo sapiens,"PLK4;TUBB;CEP152;PLK1;HAUS5;TUBB4B;TUBA1C;TUBB6;TUBA1B;HAUS8;TUBB3;CENPJ;CDK1;CEP72;NEK2","","R-HSA-380316;R-HSA-380508" R-HSA-69186,"Lagging Strand Synthesis",9,26,0.0017719621072718598,4.711487322839325E-6,3.76918985827146E-5,11,11,8.486344699891992E-4,9606,Homo sapiens,"POLA2;RFC3;FEN1;RFC4;LIG1;RFC2;PRIM1;POLD1","","R-HSA-69152;R-HSA-69074;R-HSA-69173;R-HSA-69140;R-HSA-69063;R-HSA-69127;R-HSA-69142;R-HSA-69144;R-HSA-69053;R-HSA-69068;R-HSA-69116" R-HSA-5693616,"Presynaptic phase of homologous DNA pairing and strand exchange",11,41,0.0027942479383902406,4.7615700698999675E-6,3.809256055919974E-5,5,5,3.8574294090418145E-4,9606,Homo sapiens,"BLM;RFC3;BRIP1;RFC4;RAD51;RFC2;EXO1;XRCC2;BRCA1;BRCA2","","R-HSA-5685318;R-HSA-5685230;R-HSA-5685341;R-HSA-5685242;R-HSA-5693561" R-HSA-6804116,"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest",8,20,0.0013630477748245075,5.643032098601175E-6,4.51442567888094E-5,9,17,0.001311525999074217,9606,Homo sapiens,"CCNA2;CCNE2;CDK2;E2F1;E2F7;E2F8","","R-HSA-8953037;R-HSA-6798353;R-HSA-6798304;R-HSA-69562;R-HSA-6798299;R-HSA-6798347;R-HSA-8952996;R-HSA-187934;R-HSA-8953013" R-HSA-180786,"Extension of Telomeres",14,69,0.004702514823144551,6.188281870822543E-6,4.950625496658034E-5,25,28,0.002160160469063416,9606,Homo sapiens,"BLM;FEN1;RFC3;RFC4;LIG1;RFC2;PRIM1;CHTF18;CCNA2;POLA2;POLD1;CDK2;CDK1;WRAP53","","R-HSA-164616;R-HSA-164617;R-HSA-164620;R-HSA-163090;R-HSA-174427;R-HSA-163099;R-HSA-163096;R-HSA-174425;R-HSA-174438;R-HSA-174439;R-HSA-9668597;R-HSA-9686521;R-HSA-174441;R-HSA-174446;R-HSA-174447;R-HSA-174444;R-HSA-174445;R-HSA-174451;R-HSA-174448;R-HSA-163120;R-HSA-9668902;R-HSA-174452;R-HSA-174456;R-HSA-9668904;R-HSA-176702" R-HSA-174143,"APC/C-mediated degradation of cell cycle proteins",16,92,0.006270019764192735,9.323964212160085E-6,7.459171369728068E-5,39,40,0.0030859435272334516,9606,Homo sapiens,"UBE2C;PLK1;BUB1B;AURKB;AURKA;CDC20;CCNA2;CCNB1;PTTG1;UBE2S;CDK2;CDK1;NEK2;FBXO5;BUB3;BUB1;MAD2L1","","R-HSA-174144;R-HSA-174209;R-HSA-174088;R-HSA-174159;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-188371;R-HSA-174224;R-HSA-174097;R-HSA-9686980;R-HSA-174171;R-HSA-174235;R-HSA-174104;R-HSA-174105;R-HSA-179417;R-HSA-174238;R-HSA-174174;R-HSA-188191;R-HSA-179421;R-HSA-174119;R-HSA-174058;R-HSA-174122;R-HSA-174251;R-HSA-9686969;R-HSA-174120;R-HSA-174057;R-HSA-174121;R-HSA-174255;R-HSA-141423;R-HSA-174195;R-HSA-174070;R-HSA-174132;R-HSA-141429;R-HSA-174202;R-HSA-174139;R-HSA-174203;R-HSA-174079;R-HSA-141437" R-HSA-453276,"Regulation of mitotic cell cycle",16,92,0.006270019764192735,9.323964212160085E-6,7.459171369728068E-5,39,40,0.0030859435272334516,9606,Homo sapiens,"UBE2C;PLK1;BUB1B;AURKB;AURKA;CDC20;CCNA2;CCNB1;PTTG1;UBE2S;CDK2;CDK1;NEK2;FBXO5;BUB3;BUB1;MAD2L1","","R-HSA-174144;R-HSA-174209;R-HSA-174088;R-HSA-174159;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-188371;R-HSA-174224;R-HSA-174097;R-HSA-9686980;R-HSA-174171;R-HSA-174235;R-HSA-174104;R-HSA-174105;R-HSA-179417;R-HSA-174238;R-HSA-174174;R-HSA-188191;R-HSA-179421;R-HSA-174119;R-HSA-174058;R-HSA-174122;R-HSA-174251;R-HSA-9686969;R-HSA-174120;R-HSA-174057;R-HSA-174121;R-HSA-174255;R-HSA-141423;R-HSA-174195;R-HSA-174070;R-HSA-174132;R-HSA-141429;R-HSA-174202;R-HSA-174139;R-HSA-174203;R-HSA-174079;R-HSA-141437" R-HSA-212165,"Epigenetic regulation of gene expression",20,139,0.009473182035030328,1.1933233150185352E-5,8.595600802008274E-5,20,34,0.002623051998148434,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;UHRF1;HIST1H2BI;HIST1H2BL;SUV39H1;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-5334097;R-HSA-427527;R-HSA-5334160;R-HSA-5334099;R-HSA-212263;R-HSA-5334164;R-HSA-5250938;R-HSA-5227490;R-HSA-212269;R-HSA-433672;R-HSA-427528;R-HSA-427336;R-HSA-427337;R-HSA-427383;R-HSA-5334179;R-HSA-5334151;R-HSA-5334152;R-HSA-427514;R-HSA-212222;R-HSA-212252" R-HSA-69109,"Leading Strand Synthesis",7,16,0.001090438219859606,1.2279429717154677E-5,8.595600802008274E-5,4,4,3.0859435272334514E-4,9606,Homo sapiens,"POLA2;RFC3;RFC4;RFC2;PRIM1;POLD1","","R-HSA-69074;R-HSA-69063;R-HSA-69053;R-HSA-69068" R-HSA-69091,"Polymerase switching",7,16,0.001090438219859606,1.2279429717154677E-5,8.595600802008274E-5,4,4,3.0859435272334514E-4,9606,Homo sapiens,"POLA2;RFC3;RFC4;RFC2;PRIM1;POLD1","","R-HSA-69074;R-HSA-69063;R-HSA-69053;R-HSA-69068" R-HSA-211000,"Gene Silencing by RNA",18,117,0.00797382948272337,1.353060621511748E-5,9.471424350582236E-5,2,36,0.0027773491745101066,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;MYBL1;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-5578742;R-HSA-5601926" R-HSA-8953750,"Transcriptional Regulation by E2F6",11,46,0.0031350098820963675,1.3741617778117998E-5,9.619132444682599E-5,15,33,0.0025459034099675976,9606,Homo sapiens,"RRM2;RAD51;E2F1;CDC7;BRCA1;EZH2","","R-HSA-9007561;R-HSA-9007496;R-HSA-9007467;R-HSA-8953452;R-HSA-9007591;R-HSA-9007462;R-HSA-9007514;R-HSA-9007546;R-HSA-8961982;R-HSA-8954110;R-HSA-9007582;R-HSA-8953556;R-HSA-9007605;R-HSA-9007220;R-HSA-9007606" R-HSA-8939236,"RUNX1 regulates transcription of genes involved in differentiation of HSCs",17,106,0.00722415320656989,1.3873287948329427E-5,9.711301563830599E-5,3,15,0.0011572288227125443,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-8865491;R-HSA-8865505;R-HSA-8865498" R-HSA-5693554,"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)",9,30,0.0020445716622367613,1.4520719993749154E-5,1.0164503995624408E-4,1,1,7.714858818083629E-5,9606,Homo sapiens,"RAD51AP1;BLM;BRIP1;RAD51;EXO1;XRCC2;XRCC3;BRCA1;BRCA2","","R-HSA-5693589" R-HSA-68689,"CDC6 association with the ORC:origin complex",6,11,7.496762761534792E-4,1.5237917555532832E-5,1.0666542288872982E-4,2,2,1.5429717636167257E-4,9606,Homo sapiens,"ORC6;ORC1;MCM8;E2F1;CDC6","","R-HSA-68688;R-HSA-68637" R-HSA-5651801,"PCNA-Dependent Long Patch Base Excision Repair",8,23,0.0015675049410481838,1.5302580381848507E-5,1.0711806267293955E-4,6,6,4.6289152908501776E-4,9606,Homo sapiens,"RFC3;FEN1;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-110368;R-HSA-110371;R-HSA-5651809;R-HSA-110363;R-HSA-5651805;R-HSA-110364" R-HSA-113510,"E2F mediated regulation of DNA replication",8,24,0.001635657329789409,2.0663651085550683E-5,1.4464555759885478E-4,3,4,3.0859435272334514E-4,9606,Homo sapiens,"POLA2;CCNB1;ORC6;ORC1;MCM8;PRIM1;E2F1;CDK1","","R-HSA-113504;R-HSA-113638;R-HSA-113643" R-HSA-3214847,"HATs acetylate histones",17,110,0.0074967627615347915,2.2008251907457144E-5,1.540577633522E-4,13,15,0.0011572288227125443,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;HIST1H4L;HIST1H2AH;HIST1H2AK;HIST2H2BB;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-3318486;R-HSA-3321975;R-HSA-3301237;R-HSA-3662335;R-HSA-3697008;R-HSA-3321883;R-HSA-5144542;R-HSA-3301345;R-HSA-3697920;R-HSA-3662318;R-HSA-3318415;R-HSA-3318413;R-HSA-3321805" R-HSA-69273,"Cyclin A/B1/B2 associated events during G2/M transition",9,32,0.002180876439719212,2.393553413093663E-5,1.6754873891655642E-4,21,25,0.0019287147045209073,9606,Homo sapiens,"CCNA2;CCNB2;CCNB1;CDK2;PLK1;CDK1;CDC25C;PKMYT1;CDC25A","","R-HSA-170055;R-HSA-170087;R-HSA-170116;R-HSA-170084;R-HSA-4088024;R-HSA-170149;R-HSA-170088;R-HSA-170057;R-HSA-170153;R-HSA-170158;R-HSA-170126;R-HSA-170159;R-HSA-170156;R-HSA-170131;R-HSA-170161;R-HSA-170070;R-HSA-170072;R-HSA-69754;R-HSA-69756;R-HSA-170076;R-HSA-170044" R-HSA-8856688,"Golgi-to-ER retrograde transport",20,148,0.010086553533701356,2.8599738316148482E-5,2.0019816821303937E-4,4,18,0.0013886745872550533,9606,Homo sapiens,"KIF23;KIF22;KIF11;TUBB4B;KIF15;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;KIF18B;RACGAP1;KIFC1;TUBB3;KIF4A;KIF2C;KIF20B","","R-HSA-8849350;R-HSA-6811426;R-HSA-6811423;R-HSA-8849353" R-HSA-174417,"Telomere C-strand (Lagging Strand) Synthesis",11,51,0.0034757718258024944,3.4809032877669566E-5,2.1824890430499622E-4,17,18,0.0013886745872550533,9606,Homo sapiens,"BLM;POLA2;RFC3;FEN1;RFC4;LIG1;RFC2;PRIM1;POLD1;CHTF18","","R-HSA-174438;R-HSA-174439;R-HSA-9668597;R-HSA-174441;R-HSA-174446;R-HSA-174447;R-HSA-174444;R-HSA-174445;R-HSA-174451;R-HSA-174448;R-HSA-9668902;R-HSA-174452;R-HSA-174427;R-HSA-174456;R-HSA-9668904;R-HSA-174425;R-HSA-176702" R-HSA-9609690,"HCMV Early Events",25,215,0.014652763579363457,3.590021045418723E-5,2.1824890430499622E-4,7,12,9.257830581700355E-4,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;TUBA1C;TUBB6;TUBA1B;TUBB3;HIST1H2AE;HIST1H2AD;HIST1H3B;HIST1H4L;HIST1H2AH;HIST1H2AK;HIST2H2BB;TUBB4B;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-9614816;R-HSA-9621073;R-HSA-9614343;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096;R-HSA-9614367" R-HSA-2565942,"Regulation of PLK1 Activity at G2/M Transition",15,92,0.006270019764192735,3.6374817384166036E-5,2.1824890430499622E-4,9,12,9.257830581700355E-4,9606,Homo sapiens,"PLK4;TUBB;CEP152;PLK1;HAUS5;TUBB4B;AURKB;AURKA;CCNB2;CCNB1;HAUS8;CENPJ;CDK1;CEP72;NEK2","","R-HSA-3000319;R-HSA-3002798;R-HSA-4086410;R-HSA-3002811;R-HSA-2562526;R-HSA-2574845;R-HSA-3000327;R-HSA-3000310;R-HSA-2574840" R-HSA-176417,"Phosphorylation of Emi1",5,8,5.45219109929803E-4,4.17991125023498E-5,2.507946750140988E-4,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CDC20;CCNB1;PLK1;CDK1;FBXO5","","R-HSA-174122;R-HSA-174174" R-HSA-9018519,"Estrogen-dependent gene expression",20,154,0.010495467866148708,4.9137704675517035E-5,2.948262280531022E-4,17,66,0.005091806819935195,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;KPNA2;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9009065;R-HSA-9011981;R-HSA-9011949;R-HSA-9011983;R-HSA-9011950;R-HSA-9012000;R-HSA-9009378;R-HSA-9011941;R-HSA-9012196;R-HSA-9011975;R-HSA-9009371;R-HSA-9011966;R-HSA-9011985;R-HSA-9012209;R-HSA-9011952;R-HSA-9011984;R-HSA-9012208" R-HSA-8852135,"Protein ubiquitination",14,84,0.0057248006542629315,5.1994890721718257E-5,3.1196934433030954E-4,9,32,0.002468754821786761,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;UBE2C;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H2BB;GMPPB;UBE2S;UBE2T;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC","","R-HSA-8943003;R-HSA-8852130;R-HSA-8852129;R-HSA-8943007;R-HSA-8852127;R-HSA-8943040;R-HSA-8943041;R-HSA-8942099;R-HSA-8942101" R-HSA-983231,"Factors involved in megakaryocyte development and platelet production",23,194,0.013221563415797723,5.465130997206469E-5,3.279078598323881E-4,14,43,0.0033173892917759606,9606,Homo sapiens,"HIST1H3J;KIF23;KIF22;KIF11;TUBB4B;KIF15;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;KIF18B;RACGAP1;KIFC1;TUBB3;KIF4A;CDK2;KIF2C;DOCK2;KIF20B;HIST1H3B","","R-HSA-997263;R-HSA-990478;R-HSA-1011598;R-HSA-984648;R-HSA-983266;R-HSA-984609;R-HSA-984671;R-HSA-984606;R-HSA-983259;R-HSA-994106;R-HSA-990489;R-HSA-1013881;R-HSA-984821;R-HSA-984689" R-HSA-5626467,"RHO GTPases activate IQGAPs",9,36,0.0024534859946841138,5.8763150411089704E-5,3.525789024665382E-4,5,5,3.8574294090418145E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B;IQGAP3;SCG2","","R-HSA-5626549;R-HSA-5626469;R-HSA-5672304;R-HSA-5626507;R-HSA-5672329" R-HSA-113507,"E2F-enabled inhibition of pre-replication complex formation",5,9,6.133714986710284E-4,7.252390253564833E-5,4.3514341521389E-4,1,1,7.714858818083629E-5,9606,Homo sapiens,"CCNB1;ORC6;ORC1;MCM8;CDK1","","R-HSA-113638" R-HSA-2514853,"Condensation of Prometaphase Chromosomes",6,15,0.0010222858311183807,8.387492359018811E-5,5.032495415411287E-4,4,4,3.0859435272334514E-4,9606,Homo sapiens,"CCNB2;CCNB1;CDK1;NCAPG;SMC4;NCAPH","","R-HSA-2514854;R-HSA-2529015;R-HSA-2520883;R-HSA-2529020" R-HSA-190840,"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane",7,22,0.0014993525523069584,9.000342801068761E-5,5.400205680641257E-4,1,2,1.5429717636167257E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-190520" R-HSA-110314,"Recognition of DNA damage by PCNA-containing replication complex",8,30,0.0020445716622367613,9.685881198007174E-5,5.811528718804304E-4,5,6,4.6289152908501776E-4,9606,Homo sapiens,"GMPPB;RFC3;RFC4;RFC2;POLE2;POLD1;DTL","","R-HSA-5652005;R-HSA-5655466;R-HSA-5651992;R-HSA-5652009;R-HSA-5655481" R-HSA-5685938,"HDR through Single Strand Annealing (SSA)",9,39,0.00265794316090779,1.0698358709471112E-4,6.419015225682667E-4,4,6,4.6289152908501776E-4,9606,Homo sapiens,"BLM;RFC3;BRIP1;RFC4;RAD51;RFC2;EXO1;BRCA1","","R-HSA-5686642;R-HSA-5686657;R-HSA-5693564;R-HSA-5693580" R-HSA-190872,"Transport of connexons to the plasma membrane",7,23,0.0015675049410481838,1.1810360780162288E-4,7.086216468097373E-4,1,3,2.3144576454250888E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-190520" R-HSA-174411,"Polymerase switching on the C-strand of the telomere",8,31,0.002112724050977987,1.2097775479480433E-4,7.25866528768826E-4,6,6,4.6289152908501776E-4,9606,Homo sapiens,"POLA2;RFC3;RFC4;RFC2;PRIM1;POLD1;CHTF18","","R-HSA-174448;R-HSA-174439;R-HSA-9668902;R-HSA-174452;R-HSA-9668904;R-HSA-174447" R-HSA-110373,"Resolution of AP sites via the multiple-nucleotide patch replacement pathway",8,32,0.002180876439719212,1.4985272309109288E-4,8.991163385465573E-4,14,19,0.0014658231754358896,9606,Homo sapiens,"RFC3;FEN1;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-110368;R-HSA-110371;R-HSA-5651792;R-HSA-5649873;R-HSA-5651805;R-HSA-5651773;R-HSA-5651739;R-HSA-5649883;R-HSA-5651782;R-HSA-5651809;R-HSA-110363;R-HSA-5651789;R-HSA-5651723;R-HSA-110364" R-HSA-380284,"Loss of proteins required for interphase microtubule organization from the centrosome",12,71,0.004838819600627002,1.538356893202586E-4,9.230141359215516E-4,3,3,2.3144576454250888E-4,9606,Homo sapiens,"PLK4;HAUS8;TUBB;CEP152;CENPJ;PLK1;CDK1;CEP72;NEK2;HAUS5;TUBB4B","","R-HSA-380294;R-HSA-380272;R-HSA-380303" R-HSA-380259,"Loss of Nlp from mitotic centrosomes",12,71,0.004838819600627002,1.538356893202586E-4,9.230141359215516E-4,2,2,1.5429717636167257E-4,9606,Homo sapiens,"PLK4;HAUS8;TUBB;CEP152;CENPJ;PLK1;CDK1;CEP72;NEK2;HAUS5;TUBB4B","","R-HSA-380272;R-HSA-380303" R-HSA-8866654,"E3 ubiquitin ligases ubiquitinate target proteins",11,61,0.004157295713214748,1.6555380551863674E-4,9.933228331118205E-4,6,16,0.0012343774108933806,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H2BB;GMPPB;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC","","R-HSA-8943003;R-HSA-8943007;R-HSA-8943040;R-HSA-8943041;R-HSA-8942099;R-HSA-8942101" R-HSA-6783310,"Fanconi Anemia Pathway",9,42,0.0028624003271314658,1.8467502675123537E-4,0.0011080501605074122,12,13,0.0010029316463508718,9606,Homo sapiens,"FANCI;DCLRE1B;EME1;FANCD2;UBE2T;FANCA;STRA13;FANCB","","R-HSA-6786166;R-HSA-6785126;R-HSA-6785732;R-HSA-6785986;R-HSA-6785361;R-HSA-6788385;R-HSA-6785087;R-HSA-6785342;R-HSA-6786171;R-HSA-6786155;R-HSA-6785594;R-HSA-6788392" R-HSA-389977,"Post-chaperonin tubulin folding pathway",7,25,0.0017038097185306344,1.95668282499728E-4,0.001174009694998368,9,9,6.943372936275266E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-389972;R-HSA-389956;R-HSA-389974;R-HSA-389969;R-HSA-389955;R-HSA-389964;R-HSA-389976;R-HSA-389963;R-HSA-389978" R-HSA-179409,"APC-Cdc20 mediated degradation of Nek2A",7,26,0.0017719621072718598,2.475472062480888E-4,0.0014852832374885327,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CDC20;UBE2S;UBE2C;BUB1B;NEK2;BUB3;BUB1;MAD2L1","","R-HSA-179410;R-HSA-179417;R-HSA-179421" R-HSA-2132295,"MHC class II antigen presentation",18,148,0.010086553533701356,2.525098232262213E-4,0.0015150589393573277,2,26,0.0020058632927017436,9606,Homo sapiens,"IL1R2;KIF23;KIF22;KIF11;TUBB4B;KIF15;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;RACGAP1;TUBB3;KIF4A;KIF2C","","R-HSA-2213248;R-HSA-8856157" R-HSA-5696397,"Gap-filling DNA repair synthesis and ligation in GG-NER",7,27,0.0018401144960130853,3.099612606000113E-4,0.001749913578072415,2,2,1.5429717636167257E-4,9606,Homo sapiens,"RFC3;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-5690997;R-HSA-5691001" R-HSA-176814,"Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins",12,77,0.005247733933074354,3.181672220000653E-4,0.001749913578072415,15,15,0.0011572288227125443,9606,Homo sapiens,"UBE2C;PLK1;BUB1B;CDC20;CCNA2;CCNB1;PTTG1;UBE2S;CDK1;NEK2;BUB3;BUB1;MAD2L1","","R-HSA-174144;R-HSA-174119;R-HSA-174120;R-HSA-174121;R-HSA-174255;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-174132;R-HSA-174202;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174238;R-HSA-179421" R-HSA-68911,"G2 Phase",4,7,4.7706672118857766E-4,3.49982715614483E-4,0.001749913578072415,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CCNA2;CDK2;E2F1;CDK1","","R-HSA-187937;R-HSA-187959" R-HSA-69478,"G2/M DNA replication checkpoint",4,7,4.7706672118857766E-4,3.49982715614483E-4,0.001749913578072415,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CCNB2;CCNB1;CDK1;PKMYT1","","R-HSA-170070;R-HSA-170055" R-HSA-140342,"Apoptosis induced DNA fragmentation",5,13,8.859810536359299E-4,3.920828314064595E-4,0.0019604141570322975,3,12,9.257830581700355E-4,9606,Homo sapiens,"HMGB2;HIST1H1E;HIST1H1A;HIST1H1B;HIST1H1C","","R-HSA-211239;R-HSA-266204;R-HSA-211247" R-HSA-380270,"Recruitment of mitotic centrosome proteins and complexes",12,81,0.005520343488039256,4.957284362647751E-4,0.0024786421813238757,3,3,2.3144576454250888E-4,9606,Homo sapiens,"PLK4;HAUS8;TUBB;CEP152;CENPJ;PLK1;CDK1;CEP72;NEK2;HAUS5;TUBB4B","","R-HSA-380311;R-HSA-380455;R-HSA-380283" R-HSA-141405,"Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components",6,21,0.0014312001635657329,5.0074126352595E-4,0.0025037063176297503,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CDC20;UBE2S;UBE2C;BUB1B;BUB3;BUB1;MAD2L1","","R-HSA-141429;R-HSA-141423;R-HSA-141437" R-HSA-141430,"Inactivation of APC/C via direct inhibition of the APC/C complex",6,21,0.0014312001635657329,5.0074126352595E-4,0.0025037063176297503,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CDC20;UBE2S;UBE2C;BUB1B;BUB3;BUB1;MAD2L1","","R-HSA-141423;R-HSA-141437" R-HSA-6804114,"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest",6,21,0.0014312001635657329,5.0074126352595E-4,0.0025037063176297503,4,11,8.486344699891992E-4,9606,Homo sapiens,"CCNB1;RBL1;CDK1;CDC25C;AURKB;AURKA","","R-HSA-6791235;R-HSA-6803875;R-HSA-6798268;R-HSA-6798282" R-HSA-69052,"Switching of origins to a post-replicative state",13,93,0.00633817215293396,5.040239719036332E-4,0.002520119859518166,9,9,6.943372936275266E-4,9606,Homo sapiens,"CDT1;MCM7;UBE2C;MCM8;CDC6;CCNA2;ORC6;CCNE2;ORC1;UBE2S;CDK2;CDK1;MCM5;MCM2","","R-HSA-68944;R-HSA-68947;R-HSA-68946;R-HSA-68948;R-HSA-69015;R-HSA-69016;R-HSA-69019;R-HSA-69005;R-HSA-69006" R-HSA-389960,"Formation of tubulin folding intermediates by CCT/TriC",7,30,0.0020445716622367613,5.760149693402328E-4,0.002880074846701164,2,2,1.5429717636167257E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-389954;R-HSA-389961" R-HSA-8863678,"Neurodegenerative Diseases",7,30,0.0020445716622367613,5.760149693402328E-4,0.002880074846701164,6,22,0.0016972689399783983,9606,Homo sapiens,"BCL2L11;SOD2;CDC25C;CDC25A;LMNB1","","R-HSA-8863014;R-HSA-8868340;R-HSA-8863011;R-HSA-8870703;R-HSA-8870686;R-HSA-8863674" R-HSA-8862803,"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models",7,30,0.0020445716622367613,5.760149693402328E-4,0.002880074846701164,6,22,0.0016972689399783983,9606,Homo sapiens,"BCL2L11;SOD2;CDC25C;CDC25A;LMNB1","","R-HSA-8863014;R-HSA-8868340;R-HSA-8863011;R-HSA-8870703;R-HSA-8870686;R-HSA-8863674" R-HSA-176408,"Regulation of APC/C activators between G1/S and early anaphase",12,83,0.005656648265521706,6.119631147341043E-4,0.0030598155736705213,14,14,0.001080080234531708,9606,Homo sapiens,"UBE2C;PLK1;BUB1B;CDC20;CCNA2;CCNB1;UBE2S;CDK2;CDK1;FBXO5;BUB3;BUB1;MAD2L1","","R-HSA-174209;R-HSA-174122;R-HSA-174251;R-HSA-141423;R-HSA-174159;R-HSA-188371;R-HSA-174097;R-HSA-141429;R-HSA-174139;R-HSA-174203;R-HSA-174235;R-HSA-174174;R-HSA-174079;R-HSA-141437" R-HSA-8852276,"The role of GTSE1 in G2/M progression after G2 checkpoint",12,83,0.005656648265521706,6.119631147341043E-4,0.0030598155736705213,10,10,7.714858818083629E-4,9606,Homo sapiens,"TUBA1C;CCNB2;TUBA1B;TUBB6;CCNB1;TUBB3;PLK1;CDK1;TUBB4B;GTSE1","","R-HSA-8852324;R-HSA-8852306;R-HSA-8852354;R-HSA-8852337;R-HSA-8852351;R-HSA-8852317;R-HSA-8852331;R-HSA-8852362;R-HSA-8852298;R-HSA-8852280" R-HSA-380287,"Centrosome maturation",12,83,0.005656648265521706,6.119631147341043E-4,0.0030598155736705213,6,6,4.6289152908501776E-4,9606,Homo sapiens,"PLK4;HAUS8;TUBB;CEP152;CENPJ;PLK1;CDK1;CEP72;NEK2;HAUS5;TUBB4B","","R-HSA-380311;R-HSA-380455;R-HSA-380294;R-HSA-380272;R-HSA-380303;R-HSA-380283" R-HSA-6804756,"Regulation of TP53 Activity through Phosphorylation",13,95,0.006474476930416411,6.120297988567724E-4,0.0030601489942838622,5,26,0.0020058632927017436,9606,Homo sapiens,"BLM;RFC3;RFC4;RFC2;BRCA1;AURKB;AURKA;CCNA2;TPX2;BRIP1;EXO1;CDK2;CDK1","","R-HSA-6805126;R-HSA-6805109;R-HSA-6799332;R-HSA-6805122;R-HSA-6805103" R-HSA-9645723,"Diseases of programmed cell death",7,32,0.002180876439719212,8.367206677885042E-4,0.004183603338942521,6,23,0.0017744175281592346,9606,Homo sapiens,"BCL2L11;SOD2;CDC25C;CDC25A;LMNB1","","R-HSA-8863014;R-HSA-8868340;R-HSA-8863011;R-HSA-8870703;R-HSA-8870686;R-HSA-8863674" R-HSA-1368108,"BMAL1:CLOCK,NPAS2 activates circadian gene expression",8,42,0.0028624003271314658,8.862437199200768E-4,0.004431218599600384,8,20,0.0015429717636167258,9606,Homo sapiens,"NOCT;SERPINE1;STRA13;KLF15","","R-HSA-8878679;R-HSA-5663124;R-HSA-5663138;R-HSA-5663170;R-HSA-549424;R-HSA-8878702;R-HSA-879798;R-HSA-549364" R-HSA-5620912,"Anchoring of the basal body to the plasma membrane",13,99,0.006747086485381313,8.873088598970735E-4,0.004436544299485368,8,9,6.943372936275266E-4,9606,Homo sapiens,"PLK4;HAUS8;TUBB;CEP152;CENPJ;PLK1;CDK1;CEP72;KIF24;NEK2;HAUS5;TUBB4B","","R-HSA-5626228;R-HSA-5626227;R-HSA-5626220;R-HSA-5626223;R-HSA-5626681;R-HSA-5617816;R-HSA-5626699;R-HSA-5638009" R-HSA-2980767,"Activation of NIMA Kinases NEK9, NEK6, NEK7",4,9,6.133714986710284E-4,8.893961691605057E-4,0.004446980845802528,2,4,3.0859435272334514E-4,9606,Homo sapiens,"CCNB2;CCNB1;PLK1;CDK1","","R-HSA-2984220;R-HSA-2984226" R-HSA-2995410,"Nuclear Envelope (NE) Reassembly",12,88,0.005997410209227834,0.0010060036655408222,0.005030018327704111,3,24,0.001851566116340071,9606,Homo sapiens,"TUBA1C;CCNB2;TUBA1B;TUBB6;CCNB1;TUBB3;CDK1;TUBB4B;TMPO;LMNB1","","R-HSA-9668419;R-HSA-9624800;R-HSA-2995376" R-HSA-176409,"APC/C:Cdc20 mediated degradation of mitotic proteins",11,76,0.005179581544333129,0.0010076685419433407,0.005038342709716703,13,13,0.0010029316463508718,9606,Homo sapiens,"CDC20;CCNA2;CCNB1;PTTG1;UBE2S;UBE2C;CDK1;BUB1B;NEK2;BUB3;BUB1;MAD2L1","","R-HSA-174144;R-HSA-174120;R-HSA-174121;R-HSA-174255;R-HSA-174157;R-HSA-179410;R-HSA-174227;R-HSA-174202;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174238;R-HSA-179421" R-HSA-9609646,"HCMV Infection",25,270,0.01840114496013085,0.0010347012268372424,0.005173506134186212,8,31,0.002391606233605925,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;TUBA1C;TUBB6;TUBA1B;TUBB3;HIST1H2AE;HIST1H2AD;HIST1H3B;HIST1H4L;HIST1H2AH;HIST1H2AK;HIST2H2BB;TUBB4B;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-9614816;R-HSA-9621073;R-HCY-9625991;R-HSA-9614343;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096;R-HSA-9614367" R-HSA-9619483,"Activation of AMPK downstream of NMDARs",7,34,0.002317181217201663,0.0011827149625495137,0.0059135748127475685,1,3,2.3144576454250888E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-9619542" R-HSA-9661069,"Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)",5,17,0.0011585906086008315,0.0012900422463582029,0.006450211231791014,1,1,7.714858818083629E-5,9606,Homo sapiens,"CDKN1C;CCNE2;CDK2;E2F1;CDK1","","R-HSA-9659782" R-HSA-2559584,"Formation of Senescence-Associated Heterochromatin Foci (SAHF)",5,17,0.0011585906086008315,0.0012900422463582029,0.006450211231791014,1,2,1.5429717636167257E-4,9606,Homo sapiens,"HIST1H1E;HIST1H1A;HIST1H1B;HIST1H1C;LMNB1","","R-HSA-4647594" R-HSA-9659787,"Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects",5,17,0.0011585906086008315,0.0012900422463582029,0.006450211231791014,1,2,1.5429717636167257E-4,9606,Homo sapiens,"CDKN1C;CCNE2;CDK2;E2F1;CDK1","","R-HSA-9659782" R-HSA-68867,"Assembly of the pre-replicative complex",10,68,0.004634362434403326,0.0014969072907521364,0.0065276123627588944,8,12,9.257830581700355E-4,9606,Homo sapiens,"CDT1;ORC6;MCM7;ORC1;MCM8;E2F1;MCM5;CDC6;MCM2","","R-HSA-68849;R-HSA-68688;R-HSA-68611;R-HSA-68615;R-HSA-68712;R-HSA-68826;R-HSA-68637;R-HSA-176973" R-HSA-6811442,"Intra-Golgi and retrograde Golgi-to-ER traffic",21,218,0.014857220745587133,0.0015854460101414336,0.0065276123627588944,6,48,0.003703132232680142,9606,Homo sapiens,"KIF23;KIF22;KIF11;TUBB4B;KIF15;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;KIF18B;RACGAP1;KIFC1;TUBB3;KIF4A;MAN1C1;KIF2C;KIF20B","","R-HSA-8849350;R-HSA-8847635;R-HSA-6811426;R-HSA-6811423;R-HSA-8849353;R-HSA-8847544" R-HSA-9675126,"Diseases of mitotic cell cycle",7,36,0.0024534859946841138,0.0016319030906897236,0.0065276123627588944,2,3,2.3144576454250888E-4,9606,Homo sapiens,"CDKN1C;CCNE2;UBE2S;UBE2C;CDK2;E2F1;CDK1","","R-HSA-9687377;R-HSA-9659782" R-HSA-9687139,"Aberrant regulation of mitotic cell cycle due to RB1 defects",7,36,0.0024534859946841138,0.0016319030906897236,0.0065276123627588944,2,3,2.3144576454250888E-4,9606,Homo sapiens,"CDKN1C;CCNE2;UBE2S;UBE2C;CDK2;E2F1;CDK1","","R-HSA-9687377;R-HSA-9659782" R-HSA-5689880,"Ub-specific processing proteases",20,206,0.014039392080692428,0.0018521166896539043,0.007408466758615617,8,40,0.0030859435272334516,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2AH;HIST1H2BI;HIST1H2AK;HIST1H2BL;HIST1H2BK;HIST2H2BB;HIST2H2BF;CDC25A;CDC20;CCNA2;HIST1H2AE;HIST1H2BF;HIST1H2AD;HIST1H2BE;HIST1H2BG;CLSPN;HIST1H2BB;HIST1H2BD;HIST1H2BC;BIRC3","","R-HSA-6781797;R-HSA-5696914;R-HSA-5696960;R-HSA-5690080;R-HSA-5697009;R-HSA-5696958;R-HSA-5690157;R-HSA-5696600" R-HSA-389958,"Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding",7,37,0.002521638383425339,0.0019012242154152759,0.0076048968616611035,4,6,4.6289152908501776E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-389970;R-HSA-389954;R-HSA-389980;R-HSA-389961" R-HSA-73933,"Resolution of Abasic Sites (AP sites)",8,48,0.003271314659578818,0.002033576576075613,0.008134306304302452,14,43,0.0033173892917759606,9606,Homo sapiens,"RFC3;FEN1;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-110368;R-HSA-110371;R-HSA-5651792;R-HSA-5649873;R-HSA-5651805;R-HSA-5651773;R-HSA-5651739;R-HSA-5649883;R-HSA-5651782;R-HSA-5651809;R-HSA-110363;R-HSA-5651789;R-HSA-5651723;R-HSA-110364" R-HSA-5617833,"Cilium Assembly",20,208,0.014175696858174878,0.002066238518957264,0.008264954075829056,16,50,0.0038574294090418146,9606,Homo sapiens,"PLK4;TUBB;CEP152;PLK1;KIF24;HAUS5;TUBB4B;TUBA1C;TUBB6;TUBA1B;HAUS8;TUBB3;CENPJ;TCTEX1D1;CDK1;CEP72;DYNLRB2;NEK2","","R-HSA-5624949;R-HSA-5626228;R-HSA-5625424;R-HSA-5626227;R-HSA-5625426;R-HSA-5626681;R-HSA-5624952;R-HSA-5617816;R-HSA-5618328;R-HSA-5618331;R-HSA-5638009;R-HSA-5625421;R-HSA-5626220;R-HSA-5626223;R-HSA-5625416;R-HSA-5626699" R-HSA-69183,"Processive synthesis on the lagging strand",5,19,0.0012948953860832822,0.0020873453062624225,0.00834938122504969,7,7,5.40040117265854E-4,9606,Homo sapiens,"POLA2;FEN1;LIG1;PRIM1;POLD1","","R-HSA-69152;R-HSA-69173;R-HSA-69140;R-HSA-69127;R-HSA-69142;R-HSA-69144;R-HSA-69116" R-HSA-8939211,"ESR-mediated signaling",23,256,0.017447011517753696,0.0023406862241421855,0.009362744896568742,22,110,0.008486344699891991,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;S1PR3;KPNA2;HIST1H3B;H2AFZ;HIST1H4L;MMP1;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;BTC;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9009065;R-HSA-9624272;R-HSA-9011981;R-HSA-9011949;R-HSA-9011983;R-HSA-9011950;R-HSA-9625813;R-HSA-9012000;R-HSA-9625465;R-HSA-9009378;R-HSA-9011941;R-HSA-9012196;R-HSA-9011975;R-HSA-9009371;R-HSA-9011966;R-HSA-9625482;R-HSA-9011985;R-HSA-9012209;R-HSA-9011952;R-HSA-9011984;R-HSA-9012208;R-HSA-9625487" R-HSA-68949,"Orc1 removal from chromatin",10,73,0.004975124378109453,0.0024877569814837353,0.009951027925934941,4,4,3.0859435272334514E-4,9606,Homo sapiens,"CCNA2;CDT1;ORC6;MCM7;ORC1;MCM8;CDK2;CDK1;MCM5;CDC6;MCM2","","R-HSA-68944;R-HSA-68947;R-HSA-68946;R-HSA-68948" R-HSA-9668328,"Sealing of the nuclear envelope (NE) by ESCRT-III",7,39,0.00265794316090779,0.002542157651101218,0.010168630604404871,1,7,5.40040117265854E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-9668419" R-HSA-3700989,"Transcriptional Regulation by TP53",37,486,0.03312206092823553,0.0025493238119576045,0.010197295247830418,28,259,0.0199814843388366,9606,Homo sapiens,"BLM;BRCA1;AURKB;AURKA;BRIP1;CCNB1;EXO1;E2F1;E2F7;E2F8;MAP2K6;FANCI;RFC3;RFC4;RFC2;CDC25C;CCNA2;TPX2;RBL1;CCNE2;FANCD2;CENPJ;RRAGD;CDK2;CDK1;BIRC5","","R-HSA-6797606;R-HSA-6799332;R-HSA-6803875;R-HSA-8953037;R-HSA-6798304;R-HSA-6805103;R-HSA-6805109;R-HSA-6797616;R-HSA-6793661;R-HSA-6798268;R-HSA-187934;R-HSA-6805126;R-HSA-6797766;R-HSA-6791235;R-HSA-6797763;R-HSA-6805122;R-HSA-6801666;R-HSA-6798347;R-HSA-8952996;R-HSA-6798282;R-HSA-380979;R-HSA-6798353;R-HSA-6797712;R-HSA-6802973;R-HSA-69562;R-HSA-8877691;R-HSA-6798299;R-HSA-8953013" R-HSA-176412,"Phosphorylation of the APC/C",5,20,0.0013630477748245075,0.0025986020603177007,0.010394408241270803,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CCNB1;UBE2S;UBE2C;PLK1;CDK1","","R-HSA-174119;R-HSA-174132" R-HSA-69236,"G1 Phase",8,51,0.0034757718258024944,0.0029337962521130967,0.011735185008452387,13,15,0.0011572288227125443,9606,Homo sapiens,"CDKN2D;CDKN1C;RBL1;CCNE2;CDK2;E2F1;CDK1;CKS1B","","R-HSA-182594;R-HSA-8942607;R-HSA-9018017;R-HSA-69227;R-HSA-8941895;R-HSA-8941915;R-HSA-1363328;R-HSA-1363331;R-HSA-8942803;R-HSA-1226094;R-HSA-8942836;R-HSA-1226095;R-HSA-1363274" R-HSA-69231,"Cyclin D associated events in G1",8,51,0.0034757718258024944,0.0029337962521130967,0.011735185008452387,13,15,0.0011572288227125443,9606,Homo sapiens,"CDKN2D;CDKN1C;RBL1;CCNE2;CDK2;E2F1;CDK1;CKS1B","","R-HSA-182594;R-HSA-8942607;R-HSA-9018017;R-HSA-69227;R-HSA-8941895;R-HSA-8941915;R-HSA-1363328;R-HSA-1363331;R-HSA-8942803;R-HSA-1226094;R-HSA-8942836;R-HSA-1226095;R-HSA-1363274" R-HSA-201681,"TCF dependent signaling in response to WNT",20,216,0.014720915968104683,0.0031439734698230914,0.012575893879292366,17,71,0.005477549760839377,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;TCF7;HIST2H4A;HIST1H2AE;RSPO2;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;SCG2;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-3299569;R-HSA-3361751;R-HSA-3322422;R-HSA-3451153;R-HSA-3364026;R-HSA-3322427;R-HSA-3322424;R-HSA-4411372;R-HSA-4641206;R-HSA-4641205;R-HSA-201712;R-HSA-4411351;R-HSA-4641246;R-HSA-3364042;R-HSA-3364014;R-HSA-5665608;R-HSA-3451147" R-HSA-8955332,"Carboxyterminal post-translational modifications of tubulin",8,52,0.0035439242145437195,0.0032943091324848517,0.013177236529939407,6,6,4.6289152908501776E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-8955706;R-HSA-8955869;R-HSA-8955712;R-HSA-8865774;R-HSA-8867370;R-HSA-8866105" R-HSA-190861,"Gap junction assembly",7,41,0.0027942479383902406,0.0033374933265708506,0.013349973306283403,3,16,0.0012343774108933806,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-190520;R-HSA-191737;R-HSA-190877" R-HSA-3214858,"RMTs methylate histone arginines",8,53,0.003612076603284945,0.003688292104524371,0.014753168418097484,16,22,0.0016972689399783983,9606,Homo sapiens,"HIST1H3J;H2AFZ;HIST1H4L;HIST1H2AH;HIST1H2AK;H2AFX;HIST2H4A;HIST1H4B;HIST1H2AE;HIST1H4H;HIST1H2AD;HIST1H4C;HIST1H3B;HIST1H4D;HIST1H4E","","R-HSA-5205867;R-HSA-5216234;R-HSA-5218952;R-HSA-5205799;R-HSA-5212679;R-HSA-5205798;R-HSA-5205861;R-HSA-5661117;R-HSA-5225602;R-HSA-5205824;R-HSA-5661126;R-HSA-5205822;R-HSA-5205820;R-HSA-5229203;R-HSA-5229010;R-HSA-5225649" R-HSA-75153,"Apoptotic execution phase",8,54,0.0036802289920261706,0.004117759330730775,0.0164710373229231,6,57,0.004397469526307669,9606,Homo sapiens,"OCLN;HMGB2;HIST1H1E;CLSPN;HIST1H1A;HIST1H1B;HIST1H1C;LMNB1","","R-HSA-351876;R-HSA-264871;R-HSA-211239;R-HSA-351936;R-HSA-266204;R-HSA-211247" R-HSA-437239,"Recycling pathway of L1",8,55,0.0037483813807673958,0.004584761973460583,0.01833904789384233,2,14,0.001080080234531708,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;KIF4A;TUBB4B","","R-HSA-445077;R-HSA-445071" R-HSA-4839726,"Chromatin organization",22,256,0.017447011517753696,0.00479605249367121,0.01918420997468484,72,84,0.006480481407190248,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;SUV39H1;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;HIST1H3C;H2AFZ;HIST1H4L;HIST1H2AH;HIST1H2AK;H2AFX;HIST2H2BB;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-5159245;R-HSA-5205824;R-HSA-5144542;R-HSA-5661126;R-HSA-5651654;R-HSA-5661124;R-HSA-5661125;R-HSA-5661122;R-HSA-5661123;R-HSA-5661120;R-HSA-5661121;R-HSA-5229010;R-HSA-4722133;R-HSA-5651657;R-HSA-5205867;R-HSA-5216234;R-HSA-5634802;R-HSA-3321883;R-HSA-5205861;R-HSA-5638141;R-HSA-5649764;R-HSA-3697920;R-HSA-3318415;R-HSA-4827383;R-HSA-4827382;R-HSA-3318413;R-HSA-4754187;R-HSA-5244692;R-HSA-3321975;R-HSA-3782655;R-HSA-3301237;R-HSA-5218952;R-HSA-3662335;R-HSA-3697008;R-HSA-4754176;R-HSA-5212679;R-HSA-8865613;R-HSA-4754181;R-HSA-5225602;R-HSA-3777129;R-HSA-5649799;R-HSA-3301345;R-HSA-3782637;R-HSA-3662318;R-HSA-5638157;R-HSA-5649802;R-HSA-5229203;R-HSA-3769447;R-HSA-5649800;R-HSA-5649801;R-HSA-5423117;R-HSA-3247569;R-HSA-5637686;R-HSA-3318486;R-HSA-5205799;R-HSA-5205798;R-HSA-5661116;R-HSA-5638332;R-HSA-5634750;R-HSA-5638333;R-HSA-5661117;R-HSA-5661114;R-HSA-5423038;R-HSA-5661115;R-HSA-3214912;R-HSA-5205822;R-HSA-5205820;R-HSA-4724284;R-HSA-5634729;R-HSA-5225649;R-HSA-4724279;R-HSA-3321805" R-HSA-3247509,"Chromatin modifying enzymes",22,256,0.017447011517753696,0.00479605249367121,0.01918420997468484,72,84,0.006480481407190248,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;SUV39H1;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;HIST1H3C;H2AFZ;HIST1H4L;HIST1H2AH;HIST1H2AK;H2AFX;HIST2H2BB;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-5159245;R-HSA-5205824;R-HSA-5144542;R-HSA-5661126;R-HSA-5651654;R-HSA-5661124;R-HSA-5661125;R-HSA-5661122;R-HSA-5661123;R-HSA-5661120;R-HSA-5661121;R-HSA-5229010;R-HSA-4722133;R-HSA-5651657;R-HSA-5205867;R-HSA-5216234;R-HSA-5634802;R-HSA-3321883;R-HSA-5205861;R-HSA-5638141;R-HSA-5649764;R-HSA-3697920;R-HSA-3318415;R-HSA-4827383;R-HSA-4827382;R-HSA-3318413;R-HSA-4754187;R-HSA-5244692;R-HSA-3321975;R-HSA-3782655;R-HSA-3301237;R-HSA-5218952;R-HSA-3662335;R-HSA-3697008;R-HSA-4754176;R-HSA-5212679;R-HSA-8865613;R-HSA-4754181;R-HSA-5225602;R-HSA-3777129;R-HSA-5649799;R-HSA-3301345;R-HSA-3782637;R-HSA-3662318;R-HSA-5638157;R-HSA-5649802;R-HSA-5229203;R-HSA-3769447;R-HSA-5649800;R-HSA-5649801;R-HSA-5423117;R-HSA-3247569;R-HSA-5637686;R-HSA-3318486;R-HSA-5205799;R-HSA-5205798;R-HSA-5661116;R-HSA-5638332;R-HSA-5634750;R-HSA-5638333;R-HSA-5661117;R-HSA-5661114;R-HSA-5423038;R-HSA-5661115;R-HSA-3214912;R-HSA-5205822;R-HSA-5205820;R-HSA-4724284;R-HSA-5634729;R-HSA-5225649;R-HSA-4724279;R-HSA-3321805" R-HSA-5620924,"Intraflagellar transport",8,56,0.0038165337695086213,0.005091383904282654,0.020365535617130615,6,12,9.257830581700355E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TCTEX1D1;DYNLRB2;TUBB4B","","R-HSA-5624949;R-HSA-5625424;R-HSA-5625426;R-HSA-5625421;R-HSA-5624952;R-HSA-5625416" R-HSA-157118,"Signaling by NOTCH",22,258,0.01758331629523615,0.005233771166356482,0.02093508466542593,9,154,0.01188088257984879,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;E2F1;HIST1H2AE;HIST1H2AD;HIST1H3B;DLGAP5;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;TACC3;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9604834;R-HSA-9604675;R-HSA-9018538;R-HSA-9017855;R-HSA-9018542;R-HSA-4395231;R-HSA-9604831;R-HSA-1912416;R-HSA-9604829" R-HSA-174048,"APC/C:Cdc20 mediated degradation of Cyclin B",5,24,0.001635657329789409,0.005570625537919205,0.02228250215167682,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CDC20;CCNB1;UBE2S;UBE2C;CDK1","","R-HSA-174227;R-HSA-174120;R-HSA-174157" R-HSA-73893,"DNA Damage Bypass",8,57,0.003884686158249847,0.00563973725783995,0.0225589490313598,29,34,0.002623051998148434,9606,Homo sapiens,"GMPPB;RFC3;RFC4;RFC2;POLE2;POLD1;DTL","","R-HSA-5655892;R-HSA-5656148;R-HSA-5653780;R-HSA-5653840;R-HSA-5656158;R-HSA-5655965;R-HSA-5653786;R-HSA-5655835;R-HSA-5651992;R-HSA-5653766;R-HSA-5653838;R-HSA-5654989;R-HSA-5654986;R-HSA-5653770;R-HSA-5654985;R-HSA-5652151;R-HSA-110307;R-HSA-110308;R-HSA-110311;R-HSA-5653756;R-HSA-110317;R-HSA-5653754;R-HSA-110316;R-HSA-110319;R-HSA-5655481;R-HSA-5652005;R-HSA-5655466;R-HSA-5652009;R-HSA-5656105" R-HSA-5656169,"Termination of translesion DNA synthesis",6,35,0.002385333605942888,0.006276653780437291,0.025106615121749165,8,9,6.943372936275266E-4,9606,Homo sapiens,"RFC3;RFC4;RFC2;POLE2;POLD1","","R-HSA-5653766;R-HSA-5653780;R-HSA-5653840;R-HSA-5653838;R-HSA-5653756;R-HSA-5653786;R-HSA-5653770;R-HSA-5653754" R-HSA-9646399,"Aggrephagy",7,47,0.0032031622708375927,0.006878626018483325,0.0275145040739333,4,15,0.0011572288227125443,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-9646679;R-HSA-9646390;R-HSA-9646383;R-HSA-9646685" R-HSA-179419,"APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint",9,74,0.005043276766850678,0.008407678424727116,0.033630713698908465,6,6,4.6289152908501776E-4,9606,Homo sapiens,"CDC20;CCNA2;UBE2S;UBE2C;CDK1;BUB1B;NEK2;BUB3;BUB1;MAD2L1","","R-HSA-179410;R-HSA-174171;R-HSA-174104;R-HSA-179417;R-HSA-174255;R-HSA-179421" R-HSA-162658,"Golgi Cisternae Pericentriolar Stack Reorganization",4,17,0.0011585906086008315,0.008488587589533636,0.033954350358134544,4,6,4.6289152908501776E-4,9606,Homo sapiens,"CCNB2;CCNB1;PLK1;CDK1","","R-HSA-2172194;R-HSA-2314566;R-HSA-2172183;R-HSA-2214351" R-HSA-9609736,"Assembly and cell surface presentation of NMDA receptors",7,49,0.0033394670483200438,0.008523104222423528,0.03409241688969411,2,23,0.0017744175281592346,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-9610627;R-HSA-9610408" R-HSA-9610379,"HCMV Late Events",16,175,0.011926668029714442,0.008641694309207915,0.03456677723683166,1,19,0.0014658231754358896,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;HIST1H4L;HIST1H2AH;HIST1H2AK;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HCY-9625991" R-HSA-2995383,"Initiation of Nuclear Envelope (NE) Reformation",5,27,0.0018401144960130853,0.008981084779770665,0.03592433911908266,2,7,5.40040117265854E-4,9606,Homo sapiens,"CCNB2;CCNB1;CDK1;TMPO;LMNB1","","R-HSA-9624800;R-HSA-2995376" R-HSA-5688426,"Deubiquitination",23,288,0.01962788795747291,0.00916299219554817,0.03665196878219268,18,77,0.005940441289924395,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;TNFAIP3;BRCA1;CDC20;HIST1H2AE;HIST1H2AD;CLSPN;HIST1H2AH;HIST1H2AK;HIST2H2BB;HIST2H2BF;CDC25A;CCNA2;HIST1H2BF;CDK1;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;BIRC3","","R-HSA-5690870;R-HSA-688136;R-HSA-6781797;R-HSA-5691381;R-HSA-5696914;R-HSA-5691411;R-HSA-8869506;R-HSA-5697009;R-HSA-5696958;R-HSA-5690845;R-HSA-8940100;R-HSA-5696600;R-HSA-5690790;R-HSA-5696960;R-HSA-5690080;R-HSA-5690157;R-HSA-5690827;R-HSA-5690856" R-HSA-69166,"Removal of the Flap Intermediate",4,18,0.0012267429973420569,0.010294697835925959,0.041178791343703836,4,4,3.0859435272334514E-4,9606,Homo sapiens,"POLA2;FEN1;PRIM1;POLD1","","R-HSA-69152;R-HSA-69140;R-HSA-69142;R-HSA-69144" R-HSA-112409,"RAF-independent MAPK1/3 activation",5,28,0.0019082668847543107,0.010380782556595247,0.04152313022638099,5,12,9.257830581700355E-4,9606,Homo sapiens,"DUSP4;POC1A;CDK1;IL6R","","R-HSA-109857;R-HSA-109858;R-HSA-5675376;R-HSA-112342;R-HSA-5675373" R-HSA-190828,"Gap junction trafficking",7,52,0.0035439242145437195,0.011507247859748437,0.04602899143899375,3,20,0.0015429717636167258,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-190520;R-HSA-191737;R-HSA-190877" R-HSA-389957,"Prefoldin mediated transfer of substrate to CCT/TriC",5,29,0.001976419273495536,0.011922887550788741,0.047691550203154964,2,2,1.5429717636167257E-4,9606,Homo sapiens,"TUBA1C;TUBB6;TUBB3;TUBB4B","","R-HSA-389970;R-HSA-389980" R-HSA-110312,"Translesion synthesis by REV1",4,19,0.0012948953860832822,0.012332442326180915,0.04932976930472366,4,5,3.8574294090418145E-4,9606,Homo sapiens,"RFC3;RFC4;RFC2","","R-HSA-5652151;R-HSA-110307;R-HSA-110308;R-HSA-110311" R-HSA-5696400,"Dual Incision in GG-NER",6,41,0.0027942479383902406,0.012917585375383567,0.05167034150153427,2,3,2.3144576454250888E-4,9606,Homo sapiens,"RFC3;RFC4;RFC2;POLE2;POLD1","","R-HSA-5690213;R-HSA-5690988" R-HSA-5656121,"Translesion synthesis by POLI",4,20,0.0013630477748245075,0.014611448237775493,0.052389978868114584,3,3,2.3144576454250888E-4,9606,Homo sapiens,"RFC3;RFC4;RFC2","","R-HSA-5656148;R-HSA-5656158;R-HSA-5656105" R-HSA-68881,"Mitotic Metaphase/Anaphase Transition",2,4,2.726095549649015E-4,0.015098107096391589,0.052389978868114584,1,1,7.714858818083629E-5,9606,Homo sapiens,"PLK1;FBXO5","","R-HSA-163010" R-HSA-157858,"Gap junction trafficking and regulation",7,56,0.0038165337695086213,0.016574409605213836,0.052389978868114584,3,24,0.001851566116340071,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-190520;R-HSA-191737;R-HSA-190877" R-HSA-5655862,"Translesion synthesis by POLK",4,21,0.0014312001635657329,0.017140234292313483,0.052389978868114584,3,3,2.3144576454250888E-4,9606,Homo sapiens,"RFC3;RFC4;RFC2","","R-HSA-5655892;R-HSA-5655965;R-HSA-5655835" R-HSA-5689901,"Metalloprotease DUBs",5,32,0.002180876439719212,0.017463326289371528,0.052389978868114584,2,6,4.6289152908501776E-4,9606,Homo sapiens,"HIST1H2AH;HIST1H2AK;HIST1H2AE;HIST1H2AD;BRCA1","","R-HSA-5691381;R-HSA-5691411" R-HSA-2465910,"MASTL Facilitates Mitotic Progression",3,12,8.178286648947046E-4,0.018805867177043023,0.05641760153112907,3,4,3.0859435272334514E-4,9606,Homo sapiens,"CCNB1;CDK1;MASTL","","R-HSA-2430533;R-HSA-2430535;R-HSA-2168079" R-HSA-5633007,"Regulation of TP53 Activity",15,178,0.012131125195938118,0.02069860848761851,0.062095825462855525,7,98,0.007560561641721956,9606,Homo sapiens,"BLM;RFC3;RFC4;RFC2;BRCA1;AURKB;AURKA;CCNA2;TPX2;BRIP1;EXO1;CDK2;CDK1;MAP2K6","","R-HSA-6805126;R-HSA-6805109;R-HSA-6799332;R-HSA-6805122;R-HSA-6805103;R-HSA-6793661;R-HSA-8877691" R-HSA-8953897,"Cellular responses to external stimuli",45,709,0.04832004361752879,0.02149712324568165,0.06449136973704495,52,258,0.019904335750655762,9606,Homo sapiens,"LMNB1;TUBA1C;MT2A;TUBB6;TUBA1B;TUBB3;HIST1H2AE;HIST1H2AD;HIST1H1E;HIST1H1A;HIST1H1B;HIST1H1C;H2AFZ;HIST1H2AK;H2AFX;HIST2H2BB;KLF15;CCNA2;CCNE2;RRAGD;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;E2F1;HIST1H3B;MAP2K6;CDKN2D;RPL39L;UBE2C;HIST1H4L;H2BFS;TUBB4B;SOD2;HIST1H4B;UBE2S;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;EZH2","","R-HSA-9657619;R-HSA-3790137;R-HSA-3228469;R-HSA-3790130;R-HSA-3788725;R-HSA-3240765;R-HSA-9645598;R-HSA-3788724;R-HSA-3240766;R-HSA-9640195;R-HSA-3229089;R-HSA-3223200;R-HSA-9646468;R-HSA-3788705;R-HSA-450333;R-HSA-187934;R-HSA-3788708;R-HSA-3229102;R-HSA-3209109;R-HSA-9640254;R-HSA-3209096;R-HSA-9645608;R-HSA-69562;R-HSA-9640237;R-HSA-182594;R-HSA-5662608;R-HSA-3240957;R-HSA-5662598;R-HSA-3299680;R-HSA-3785711;R-HSA-3240295;R-HSA-9633742;R-HSA-5662986;R-HSA-3240787;R-HSA-9633008;R-HSA-9639287;R-HSA-9639286;R-HSA-3238999;R-HSA-4647594;R-HSA-3788745;R-HSA-3222593;R-HSA-9640167;R-HSA-3788748;R-HSA-5618080;R-HSA-3240777;R-HSA-9640168;R-HSA-9640175;R-HSA-450296;R-HSA-3240783;R-HSA-9634669;R-HSA-3240782;R-HSA-9633005" R-HSA-2262752,"Cellular responses to stress",44,691,0.04709330062018674,0.02176901951287835,0.06530705853863505,49,227,0.017512729517049838,9606,Homo sapiens,"LMNB1;TUBA1C;TUBB6;TUBA1B;TUBB3;HIST1H2AE;HIST1H2AD;HIST1H1E;HIST1H1A;HIST1H1B;HIST1H1C;H2AFZ;HIST1H2AK;H2AFX;HIST2H2BB;KLF15;CCNA2;CCNE2;RRAGD;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;E2F1;HIST1H3B;MAP2K6;CDKN2D;RPL39L;UBE2C;HIST1H4L;H2BFS;TUBB4B;SOD2;HIST1H4B;UBE2S;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;EZH2","","R-HSA-9657619;R-HSA-3790137;R-HSA-3228469;R-HSA-3790130;R-HSA-3788725;R-HSA-3240765;R-HSA-9645598;R-HSA-3788724;R-HSA-3240766;R-HSA-9640195;R-HSA-3229089;R-HSA-3223200;R-HSA-9646468;R-HSA-3788705;R-HSA-450333;R-HSA-187934;R-HSA-3788708;R-HSA-3229102;R-HSA-3209109;R-HSA-9640254;R-HSA-3209096;R-HSA-9645608;R-HSA-69562;R-HSA-9640237;R-HSA-182594;R-HSA-3240957;R-HSA-3299680;R-HSA-3785711;R-HSA-3240295;R-HSA-9633742;R-HSA-3240787;R-HSA-9633008;R-HSA-9639287;R-HSA-9639286;R-HSA-3238999;R-HSA-4647594;R-HSA-3788745;R-HSA-3222593;R-HSA-9640167;R-HSA-3788748;R-HSA-5618080;R-HSA-3240777;R-HSA-9640168;R-HSA-9640175;R-HSA-450296;R-HSA-3240783;R-HSA-9634669;R-HSA-3240782;R-HSA-9633005" R-HSA-174184,"Cdc20:Phospho-APC/C mediated degradation of Cyclin A",8,73,0.004975124378109453,0.02184794959656189,0.06554384878968567,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CDC20;CCNA2;UBE2S;UBE2C;CDK1;BUB1B;BUB3;BUB1;MAD2L1","","R-HSA-174171;R-HSA-174104;R-HSA-174255" R-HSA-170145,"Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes",2,5,3.407619437061269E-4,0.0228893918702483,0.0686681756107449,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CCNA2;CDK1","","R-HSA-69754;R-HSA-69756" R-HSA-4419969,"Depolymerisation of the Nuclear Lamina",4,23,0.0015675049410481838,0.02297563265620084,0.06892689796860252,3,6,4.6289152908501776E-4,9606,Homo sapiens,"CCNB1;CDK1;TMPO;LMNB1","","R-HSA-5195402;R-HSA-5229194;R-HSA-5244669" R-HSA-110056,"MAPK3 (ERK1) activation",3,13,8.859810536359299E-4,0.02312265173514383,0.06936795520543149,2,4,3.0859435272334514E-4,9606,Homo sapiens,"CDK1;IL6R","","R-HSA-109857;R-HSA-112342" R-HSA-6796648,"TP53 Regulates Transcription of DNA Repair Genes",9,89,0.006065562597969059,0.024511309301028295,0.07353392790308488,3,17,0.001311525999074217,9606,Homo sapiens,"FANCI;FANCD2;BRCA1","","R-HSA-6797606;R-HSA-6797712;R-HSA-6797616" R-HSA-110313,"Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template",6,48,0.003271314659578818,0.025552184864648053,0.07665655459394416,24,28,0.002160160469063416,9606,Homo sapiens,"RFC3;RFC4;RFC2;POLE2;POLD1","","R-HSA-5652151;R-HSA-5655892;R-HSA-110307;R-HSA-5656148;R-HSA-5653780;R-HSA-110308;R-HSA-110311;R-HSA-5653840;R-HSA-5656158;R-HSA-5653756;R-HSA-5655965;R-HSA-110317;R-HSA-5653786;R-HSA-5653754;R-HSA-5655835;R-HSA-110316;R-HSA-110319;R-HSA-5653766;R-HSA-5653838;R-HSA-5654989;R-HSA-5654986;R-HSA-5653770;R-HSA-5656105;R-HSA-5654985" R-HSA-110320,"Translesion Synthesis by POLH",4,24,0.001635657329789409,0.026293705952435187,0.07888111785730556,6,8,6.171887054466903E-4,9606,Homo sapiens,"RFC3;RFC4;RFC2","","R-HSA-5654989;R-HSA-5654986;R-HSA-110317;R-HSA-110316;R-HSA-110319;R-HSA-5654985" R-HSA-6811436,"COPI-independent Golgi-to-ER retrograde traffic",7,63,0.004293600490697199,0.02891732801928326,0.08675198405784978,2,7,5.40040117265854E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-8849350;R-HSA-8849353" R-HSA-4615885,"SUMOylation of DNA replication proteins",6,50,0.003407619437061269,0.030286917529109614,0.09086075258732884,5,8,6.171887054466903E-4,9606,Homo sapiens,"TOP2A;INCENP;BIRC5;CDCA8;AURKB;AURKA","","R-HSA-4641350;R-HSA-5228525;R-HSA-4641342;R-HSA-4655404;R-HSA-4655355" R-HSA-8952158,"RUNX3 regulates BCL2L11 (BIM) transcription",2,6,4.089143324473523E-4,0.03198457545138189,0.09595372635414567,2,2,1.5429717636167257E-4,9606,Homo sapiens,"BCL2L11","","R-HSA-8952232;R-HSA-8952226" R-HSA-69200,"Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes",2,6,4.089143324473523E-4,0.03198457545138189,0.09595372635414567,1,1,7.714858818083629E-5,9606,Homo sapiens,"CCNE2;CDK2;CDK1","","R-HSA-188390" R-HSA-68616,"Assembly of the ORC complex at the origin of replication",2,6,4.089143324473523E-4,0.03198457545138189,0.09595372635414567,2,5,3.8574294090418145E-4,9606,Homo sapiens,"ORC6;ORC1","","R-HSA-68611;R-HSA-68615" R-HSA-75035,"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex",3,15,0.0010222858311183807,0.03322838072635936,0.09968514217907809,4,5,3.8574294090418145E-4,9606,Homo sapiens,"CCNB1;CDK1;CDC25C","","R-HSA-75809;R-HSA-170070;R-HSA-75016;R-HSA-9029987" R-HSA-113501,"Inhibition of replication initiation of damaged DNA by RB1/E2F1",3,15,0.0010222858311183807,0.03322838072635936,0.09968514217907809,2,3,2.3144576454250888E-4,9606,Homo sapiens,"POLA2;PRIM1;E2F1","","R-HSA-113504;R-HSA-113643" R-HSA-6782210,"Gap-filling DNA repair synthesis and ligation in TC-NER",7,66,0.004498057656920875,0.03572398761081497,0.1071719628324449,2,2,1.5429717636167257E-4,9606,Homo sapiens,"RFC3;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-6782227;R-HSA-6782208" R-HSA-8878171,"Transcriptional regulation by RUNX1",19,261,0.017787773461459825,0.03758247222398825,0.11274741667196475,25,132,0.01018361363987039,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;HIST1H2AE;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;OCLN;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-8936584;R-HSA-8937097;R-HSA-8937037;R-HSA-8937113;R-HSA-8937050;R-HSA-8865491;R-HSA-8936989;R-HSA-8937118;R-HSA-8936979;R-HSA-8865498;R-HSA-8936599;R-HSA-8936616;R-HSA-8935980;R-HSA-8936621;R-HSA-8865505;R-HSA-8936608;R-HSA-8936481;R-HSA-8936995;R-HSA-8937016;R-HSA-8935740;R-HSA-8937022;R-HSA-8935730;R-HSA-8935731;R-HSA-8935988;R-HSA-8936628" R-HSA-9006931,"Signaling by Nuclear Receptors",26,385,0.02623866966537177,0.03777511020869673,0.11332533062609018,28,191,0.014735380342539732,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;RDH10;HIST1H2AE;HIST1H2AD;S1PR3;KPNA2;HIST1H3B;H2AFZ;HIST1H4L;MMP1;HIST1H2AK;AKR1C1;H2AFX;AKR1C3;HIST2H2BB;H2BFS;BTC;HIST1H4B;FABP5;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-9624272;R-HSA-9011981;R-HSA-9011983;R-HSA-5362518;R-HSA-9625813;R-HSA-5422942;R-HSA-9011975;R-HSA-9009371;R-HSA-9625482;R-HSA-9011985;R-HSA-9011984;R-HSA-9625487;R-HSA-9009065;R-HSA-5615668;R-HSA-5634100;R-HSA-9011949;R-HSA-5622129;R-HSA-9011950;R-HSA-9012000;R-HSA-9625465;R-HSA-9009378;R-HSA-9011941;R-HSA-9012196;R-HSA-9011966;R-HSA-9012209;R-HSA-9011952;R-HSA-9012208;R-HSA-5633256" R-HSA-68952,"DNA replication initiation",3,16,0.001090438219859606,0.03900908448362084,0.11702725345086251,2,2,1.5429717636167257E-4,9606,Homo sapiens,"POLA2;PRIM1;POLE2","","R-HSA-68913;R-HSA-68950" R-HSA-9636003,"NEIL3-mediated resolution of ICLs",1,1,6.815238874122537E-5,0.04515751970727899,0.13547255912183698,2,2,1.5429717636167257E-4,9606,Homo sapiens,"NEIL3","","R-HSA-9636008;R-HSA-9635996" R-HSA-9629232,"Defective Base Excision Repair Associated with NEIL3",1,1,6.815238874122537E-5,0.04515751970727899,0.13547255912183698,1,1,7.714858818083629E-5,9606,Homo sapiens,"NEIL3","","R-HSA-9629245" R-HSA-390466,"Chaperonin-mediated protein folding",9,100,0.006815238874122538,0.04553061182356244,0.13659183547068732,5,19,0.0014658231754358896,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;CCNE2;TUBB3;TUBB4B;WRAP53","","R-HSA-390470;R-HSA-389970;R-HSA-389954;R-HSA-389980;R-HSA-389961" R-HSA-3371497,"HSP90 chaperone cycle for steroid hormone receptors (SHR)",7,70,0.004770667211885776,0.04633499869122326,0.13900499607366978,1,12,9.257830581700355E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-5618080" R-HSA-212436,"Generic Transcription Pathway",86,1554,0.10590881210386424,0.046425428483937825,0.13927628545181348,96,824,0.0635704366610091,9606,Homo sapiens,"SERPINE1;BRCA1;EXO1;HIST1H2AE;HIST1H2AD;MYBL2;RFC3;RFC4;H2AFZ;RFC2;HIST1H2AK;H2AFX;HIST2H2BB;CDC25C;CCNA2;RBL1;CCNE2;FANCD2;GPRIN1;ZNF724P;RRAGD;HIST1H2BF;BIRC5;HIST1H2BE;HIST1H2BG;HIST1H2BB;SCG2;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;TCF7;HIST1H2BK;AURKB;AURKA;HIST2H4A;BRIP1;CCNB1;BCL2L11;E2F1;HIST1H3B;E2F7;MAP2K6;E2F8;FANCI;RRM2;ABCA6;UBE2C;HIST1H4L;ATAD2;NR0B1;CDC7;H2BFS;SOD2;TPX2;OCLN;BMP2;RAD51;HIST1H4B;UBE2S;CENPJ;CDK2;CDK1;HIST1H4H;HIST1H4C;ZNF730;HIST1H4D;HIST1H4E;ZNF530;EZH2","","R-HSA-8936584;R-HSA-8937097;R-HSA-9007496;R-HSA-6799332;R-HSA-6798304;R-HSA-6805103;R-HSA-3790130;R-HSA-9009282;R-HSA-8951428;R-HSA-8937113;R-HSA-8937369;R-HSA-9625091;R-HSA-6805109;R-HSA-9007514;R-HSA-382096;R-HSA-8936989;R-HSA-9023132;R-HSA-9625092;R-HSA-8937118;R-HSA-8936979;R-HSA-187934;R-HSA-8936599;R-HSA-8952232;R-HSA-8936616;R-HSA-9622579;R-HSA-6797766;R-HSA-6791235;R-HSA-6797763;R-HSA-8935980;R-HSA-8936621;R-HSA-9617972;R-HSA-8936608;R-HSA-8936481;R-HSA-8952226;R-HSA-8869549;R-HSA-8936995;R-HSA-8952996;R-HSA-6798282;R-HSA-8937016;R-HSA-2186643;R-HSA-9007546;R-HSA-8935740;R-HSA-380979;R-HSA-8937022;R-HSA-8961982;R-HSA-8869566;R-HSA-2127257;R-HSA-8935730;R-HSA-9617832;R-HSA-9617833;R-HSA-8935731;R-HSA-69562;R-HSA-8935988;R-HSA-8936628;R-HSA-6798299;R-HSA-8953013;R-HSA-9622572;R-HSA-9007561;R-HSA-6797606;R-HSA-6803875;R-HSA-8937037;R-HSA-8953037;R-HSA-9008832;R-HSA-975040;R-HSA-9007707;R-HSA-8937050;R-HSA-8865491;R-HSA-1484099;R-HSA-9007582;R-HSA-6797616;R-HSA-6793661;R-HSA-6798268;R-HSA-8953556;R-HSA-8865498;R-HSA-9622604;R-HSA-6805126;R-HSA-9007467;R-HSA-8953452;R-HSA-6805122;R-HSA-6801666;R-HSA-376419;R-HSA-8865505;R-HSA-6798347;R-HSA-9007591;R-HSA-9007462;R-HSA-9021946;R-HSA-9021948;R-HSA-6798353;R-HSA-8954110;R-HSA-6797712;R-HSA-2106586;R-HSA-6802973;R-HSA-8877691;R-HSA-9007605;R-HSA-9007220;R-HSA-9007606" R-HSA-5635851,"GLI proteins bind promoters of Hh responsive genes to promote transcription",2,8,5.45219109929803E-4,0.053562805902579225,0.16068841770773767,4,4,3.0859435272334514E-4,9606,Homo sapiens,"GLI1","","R-HSA-5635846;R-HSA-5635853;R-HSA-5635848;R-HSA-5635850" R-HSA-8935964,"RUNX1 regulates expression of components of tight junctions",2,8,5.45219109929803E-4,0.053562805902579225,0.16068841770773767,2,6,4.6289152908501776E-4,9606,Homo sapiens,"OCLN","","R-HSA-8935980;R-HSA-8935988" R-HSA-69202,"Cyclin E associated events during G1/S transition ",8,88,0.005997410209227834,0.054624926618847436,0.1638747798565423,17,20,0.0015429717636167258,9606,Homo sapiens,"CCNA2;CCNE2;CDK2;E2F1;CDK1;LIN9;CDC25A;CKS1B","","R-HSA-188386;R-HSA-187552;R-HSA-187520;R-HSA-188390;R-HSA-69191;R-HSA-69195;R-HSA-69199;R-HSA-157906;R-HSA-8848436;R-HSA-187574;R-HSA-187575;R-HSA-8932400;R-HSA-8848414;R-HSA-188345;R-HSA-69562;R-HSA-187545;R-HSA-188350" R-HSA-400253,"Circadian Clock",9,104,0.007087848429087439,0.05548210731118186,0.16644632193354558,9,59,0.004551766702669341,9606,Homo sapiens,"NOCT;SERPINE1;ELOVL3;STRA13;KLF15","","R-HSA-8878679;R-HSA-5663252;R-HSA-5663124;R-HSA-5663138;R-HSA-5663170;R-HSA-549424;R-HSA-8878702;R-HSA-879798;R-HSA-549364" R-HSA-174178,"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1",7,74,0.005043276766850678,0.058774505242578545,0.17632351572773564,6,6,4.6289152908501776E-4,9606,Homo sapiens,"CDC20;PTTG1;UBE2S;UBE2C;PLK1;AURKB;AURKA","","R-HSA-174195;R-HSA-9686980;R-HSA-174088;R-HSA-9686969;R-HSA-174105;R-HSA-188191" R-HSA-69656,"Cyclin A:Cdk2-associated events at S phase entry",8,90,0.006133714986710284,0.06056390214791196,0.1816917064437359,16,19,0.0014658231754358896,9606,Homo sapiens,"CCNA2;CCNE2;CDK2;E2F1;CDK1;LIN9;CDC25A;CKS1B","","R-HSA-187552;R-HSA-187520;R-HSA-174273;R-HSA-174054;R-HSA-187948;R-HSA-187916;R-HSA-187949;R-HSA-8848436;R-HSA-187574;R-HSA-187575;R-HSA-174164;R-HSA-8848414;R-HSA-188345;R-HSA-187545;R-HSA-187934;R-HSA-174110" R-HSA-391251,"Protein folding",9,106,0.00722415320656989,0.06094819702598464,0.18284459107795392,14,28,0.002160160469063416,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;CCNE2;TUBB3;TUBB4B;WRAP53","","R-HSA-389956;R-HSA-390470;R-HSA-389955;R-HSA-389954;R-HSA-389964;R-HSA-389961;R-HSA-389963;R-HSA-389972;R-HSA-389974;R-HSA-389969;R-HSA-389970;R-HSA-389980;R-HSA-389976;R-HSA-389978" R-HSA-8869496,"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation",2,9,6.133714986710284E-4,0.06580673944003634,0.19742021832010903,2,7,5.40040117265854E-4,9606,Homo sapiens,"MYBL2","","R-HSA-8869566;R-HSA-8869549" R-HSA-174414,"Processive synthesis on the C-strand of the telomere",4,33,0.0022490288284604375,0.06858526548089094,0.20575579644267283,7,7,5.40040117265854E-4,9606,Homo sapiens,"BLM;FEN1;LIG1;POLD1","","R-HSA-174451;R-HSA-174438;R-HSA-174456;R-HSA-174441;R-HSA-174446;R-HSA-174444;R-HSA-174445" R-HSA-193807,"Synthesis of bile acids and bile salts via 27-hydroxycholesterol",4,34,0.002317181217201663,0.07465123470619328,0.22395370411857984,2,12,9.257830581700355E-4,9606,Homo sapiens,"AKR1C1;AKR1C3;AKR1C2","","R-HSA-193841;R-HSA-193800" R-HSA-1445148,"Translocation of SLC2A4 (GLUT4) to the plasma membrane",7,79,0.005384038710556805,0.07696328233198857,0.2308898469959657,1,15,0.0011572288227125443,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-2316347" R-HSA-5357801,"Programmed Cell Death",14,197,0.0134260205820214,0.07776386941999958,0.23329160825999873,20,154,0.01188088257984879,9606,Homo sapiens,"DAPK2;HMGB2;LMNB1;OCLN;BCL2L11;E2F1;HIST1H1E;BMF;CLSPN;CD14;HIST1H1A;HIST1H1B;BIRC3;HIST1H1C","","R-HSA-351876;R-HSA-2562564;R-HSA-264871;R-HSA-508163;R-HSA-211239;R-HSA-508162;R-HSA-351936;R-HSA-139908;R-HSA-139909;R-HSA-418849;R-HSA-139918;R-HSA-211247;R-HSA-139919;R-HSA-5675470;R-HSA-266204;R-HSA-5213462;R-HSA-140217;R-HSA-4331327;R-HSA-4331324;R-HSA-140221" R-HSA-438064,"Post NMDA receptor activation events",8,96,0.006542629319157636,0.08073281408284927,0.2421984422485478,3,39,0.003008794939052615,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B;KPNA2","","R-HSA-9619542;R-HSA-9619127;R-HSA-112282" R-HSA-176407,"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase",3,22,0.0014993525523069584,0.08323468257045274,0.24970404771135823,2,3,2.3144576454250888E-4,9606,Homo sapiens,"CDC20;UBE2S;UBE2C","","R-HSA-174224;R-HSA-174070" R-HSA-5358606,"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)",3,22,0.0014993525523069584,0.08323468257045274,0.24970404771135823,4,9,6.943372936275266E-4,9606,Homo sapiens,"LIG1;EXO1;POLD1","","R-HSA-5358545;R-HSA-5358592;R-HSA-5358579;R-HSA-5358619" R-HSA-5358565,"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)",3,22,0.0014993525523069584,0.08323468257045274,0.24970404771135823,4,10,7.714858818083629E-4,9606,Homo sapiens,"LIG1;EXO1;POLD1","","R-HSA-5358592;R-HSA-5358579;R-HSA-5358597;R-HSA-5358599" R-HSA-2980766,"Nuclear Envelope Breakdown",6,65,0.00442990526817965,0.08382068148604482,0.25146204445813447,7,13,0.0010029316463508718,9606,Homo sapiens,"CCNB2;CCNB1;PLK1;CDK1;TMPO;LMNB1","","R-HSA-2984220;R-HSA-5195402;R-HSA-5229194;R-HSA-2993898;R-HSA-5244669;R-HSA-2990882;R-HSA-2984226" R-HSA-5579032,"Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD)",1,2,1.3630477748245075E-4,0.0882787093616243,0.2648361280848729,1,1,7.714858818083629E-5,9606,Homo sapiens,"TBXAS1","","R-HSA-5603275" R-HSA-5340573,"WNT ligand secretion is abrogated by the PORCN inhibitor LGK974",1,2,1.3630477748245075E-4,0.0882787093616243,0.2648361280848729,1,1,7.714858818083629E-5,9606,Homo sapiens,"PORCN","","R-HSA-5340560" R-HSA-5358508,"Mismatch Repair",3,23,0.0015675049410481838,0.09205810776885681,0.27617432330657044,6,17,0.001311525999074217,9606,Homo sapiens,"LIG1;EXO1;POLD1","","R-HSA-5358545;R-HSA-5358592;R-HSA-5358579;R-HSA-5358597;R-HSA-5358599;R-HSA-5358619" R-HSA-111453,"BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members",2,11,7.496762761534792E-4,0.09266910297711861,0.27800730893135583,2,4,3.0859435272334514E-4,9606,Homo sapiens,"BCL2L11;BMF","","R-HSA-508163;R-HSA-508162" R-HSA-195721,"Signaling by WNT",21,332,0.022626593062086826,0.0955530835565026,0.2866592506695078,24,157,0.012112328344391297,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;TCF7;HIST2H4A;PORCN;HIST1H2AE;RSPO2;HIST1H2AD;HIST1H3B;H2AFZ;HIST1H4L;HIST1H2AK;H2AFX;HIST2H2BB;H2BFS;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;HIST1H2BB;HIST1H4D;SCG2;HIST1H4E;HIST1H2BD;HIST1H2BC","","R-HSA-8944362;R-HSA-3299569;R-HSA-3361751;R-HSA-3322422;R-HSA-3451153;R-HSA-4411365;R-HSA-8944352;R-HSA-3364026;R-HSA-4641231;R-HSA-3322427;R-HSA-3322424;R-HSA-5229348;R-HSA-4411372;R-HSA-4641206;R-HSA-4641205;R-HSA-201712;R-HSA-4411351;R-HSA-8944349;R-HSA-3238694;R-HSA-4641246;R-HSA-3364042;R-HSA-3364014;R-HSA-5665608;R-HSA-3451147" R-HSA-6782135,"Dual incision in TC-NER",6,68,0.004634362434403326,0.0984404854097598,0.2953214562292794,2,7,5.40040117265854E-4,9606,Homo sapiens,"RFC3;RFC4;RFC2;POLE2;POLD1","","R-HSA-6782211;R-HSA-6782224" R-HSA-1852241,"Organelle biogenesis and maintenance",21,335,0.0228310502283105,0.10209740399317846,0.3062922119795354,17,86,0.006634778583551921,9606,Homo sapiens,"PLK4;TUBB;CEP152;PLK1;KIF24;HAUS5;TUBB4B;SOD2;TUBA1C;TUBB6;TUBA1B;HAUS8;TUBB3;CENPJ;TCTEX1D1;CDK1;CEP72;DYNLRB2;NEK2","","R-HSA-5624949;R-HSA-5626228;R-HSA-5625424;R-HSA-5626227;R-HSA-5625426;R-HSA-5626681;R-HSA-5624952;R-HSA-5617816;R-HSA-5618328;R-HSA-5618331;R-HSA-5638009;R-HSA-5688289;R-HSA-5625421;R-HSA-5626220;R-HSA-5626223;R-HSA-5625416;R-HSA-5626699" R-HSA-6781827,"Transcription-Coupled Nucleotide Excision Repair (TC-NER)",7,85,0.0057929530430041575,0.10266490663073125,0.30671800539763416,4,17,0.001311525999074217,9606,Homo sapiens,"RFC3;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-6782227;R-HSA-6782211;R-HSA-6782208;R-HSA-6782224" R-HSA-109581,"Apoptosis",13,189,0.012880801472091597,0.10427933780393461,0.30671800539763416,18,141,0.010877950933497917,9606,Homo sapiens,"DAPK2;HMGB2;LMNB1;OCLN;BCL2L11;E2F1;HIST1H1E;BMF;CLSPN;CD14;HIST1H1A;HIST1H1B;HIST1H1C","","R-HSA-351876;R-HSA-2562564;R-HSA-264871;R-HSA-508163;R-HSA-211239;R-HSA-508162;R-HSA-351936;R-HSA-139908;R-HSA-139909;R-HSA-418849;R-HSA-139918;R-HSA-211247;R-HSA-139919;R-HSA-266204;R-HSA-140217;R-HSA-4331327;R-HSA-4331324;R-HSA-140221" R-HSA-112411,"MAPK1 (ERK2) activation",2,12,8.178286648947046E-4,0.10709640040979351,0.30671800539763416,1,3,2.3144576454250888E-4,9606,Homo sapiens,"IL6R","","R-HSA-109858" R-HSA-2173796,"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription",4,39,0.00265794316090779,0.10878698643851292,0.30671800539763416,4,17,0.001311525999074217,9606,Homo sapiens,"RBL1;SERPINE1;SCG2","","R-HSA-2186643;R-HSA-1484099;R-HSA-2127257;R-HSA-2106586" R-HSA-9619665,"EGR2 and SOX10-mediated initiation of Schwann cell myelination",4,39,0.00265794316090779,0.10878698643851292,0.30671800539763416,6,26,0.0020058632927017436,9606,Homo sapiens,"MPZ;ADGRG6;MBP","","R-HSA-9614787;R-HSA-9614273;R-HSA-9614790;R-HSA-9614773;R-HSA-9614271;R-HSA-9613644" R-HSA-2468052,"Establishment of Sister Chromatid Cohesion",2,13,8.859810536359299E-4,0.12207199246924094,0.30671800539763416,4,4,3.0859435272334514E-4,9606,Homo sapiens,"CDCA5;ESCO2","","R-HSA-2468039;R-HSA-2473152;R-HSA-2473151;R-HSA-2468041" R-HSA-9663891,"Selective autophagy",7,89,0.006065562597969059,0.12208488066904444,0.30671800539763416,4,48,0.003703132232680142,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-9646679;R-HSA-9646390;R-HSA-9646383;R-HSA-9646685" R-HSA-9657689,"Defective SERPING1 causes hereditary angioedema",1,3,2.0445716622367614E-4,0.12945526558271647,0.30671800539763416,3,3,2.3144576454250888E-4,9606,Homo sapiens,"SERPING1","","R-HSA-9651456;R-HSA-9651467;R-HSA-9650447" R-HSA-166020,"Transfer of LPS from LBP carrier to CD14",1,3,2.0445716622367614E-4,0.12945526558271647,0.30671800539763416,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CD14","","R-HSA-166038;R-HSA-169719" R-HSA-352238,"Breakdown of the nuclear lamina",1,3,2.0445716622367614E-4,0.12945526558271647,0.30671800539763416,1,3,2.3144576454250888E-4,9606,Homo sapiens,"LMNB1","","R-HSA-264871" R-HSA-1482839,"Acyl chain remodelling of PE",4,42,0.0028624003271314658,0.13207317387950324,0.30671800539763416,4,9,6.943372936275266E-4,9606,Homo sapiens,"RARRES3;CFI;NES","","R-HSA-1482646;R-HSA-1602398;R-HSA-8858298;R-HSA-1482667" R-HSA-69017,"CDK-mediated phosphorylation and removal of Cdc6",6,75,0.005111429155591904,0.13735429651339592,0.30671800539763416,4,4,3.0859435272334514E-4,9606,Homo sapiens,"CCNA2;CCNE2;UBE2S;UBE2C;CDK2;CDK1;CDC6","","R-HSA-69015;R-HSA-69016;R-HSA-69005;R-HSA-69006" R-HSA-5696399,"Global Genome Nucleotide Excision Repair (GG-NER)",7,92,0.006270019764192735,0.13779488871009338,0.30671800539763416,4,20,0.0015429717636167258,9606,Homo sapiens,"RFC3;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-5690213;R-HSA-5690997;R-HSA-5690988;R-HSA-5691001" R-HSA-193775,"Synthesis of bile acids and bile salts via 24-hydroxycholesterol",4,43,0.0029305527158726913,0.140256287792084,0.30671800539763416,2,28,0.002160160469063416,9606,Homo sapiens,"AKR1C1;AKR1C3;AKR1C2","","R-HSA-193781;R-HSA-193758" R-HSA-68827,"CDT1 association with the CDC6:ORC:origin complex",5,59,0.0040209909357322975,0.14063318884587672,0.30671800539763416,2,3,2.3144576454250888E-4,9606,Homo sapiens,"CDT1;ORC6;ORC1;MCM8;CDC6","","R-HSA-68712;R-HSA-68826" R-HSA-373760,"L1CAM interactions",9,130,0.0088598105363593,0.1525614682168439,0.30671800539763416,3,54,0.00416602376176516,9606,Homo sapiens,"TUBA1C;TUBA1B;GAP43;TUBB6;TUBB3;KIF4A;TUBB4B","","R-HSA-445077;R-HSA-8933328;R-HSA-445071" R-HSA-110362,"POLB-Dependent Long Patch Base Excision Repair",2,15,0.0010222858311183807,0.15335900269881708,0.30671800539763416,8,10,7.714858818083629E-4,9606,Homo sapiens,"FEN1;LIG1","","R-HSA-5651782;R-HSA-5651792;R-HSA-5649873;R-HSA-5651789;R-HSA-5651773;R-HSA-5651739;R-HSA-5651723;R-HSA-5649883" R-HSA-5685939,"HDR through MMEJ (alt-NHEJ)",2,15,0.0010222858311183807,0.15335900269881708,0.30671800539763416,4,8,6.171887054466903E-4,9606,Homo sapiens,"POLQ;FEN1","","R-HSA-5687653;R-HSA-5687664;R-HSA-5687484;R-HSA-5687640" R-HSA-68884,"Mitotic Telophase/Cytokinesis",2,15,0.0010222858311183807,0.15335900269881708,0.30671800539763416,2,4,3.0859435272334514E-4,9606,Homo sapiens,"PLK1;KIF23","","R-HSA-156723;R-HSA-156673" R-HSA-202670,"ERKs are inactivated",2,15,0.0010222858311183807,0.15335900269881708,0.30671800539763416,1,2,1.5429717636167257E-4,9606,Homo sapiens,"DUSP4;POC1A","","R-HSA-203797" R-HSA-442755,"Activation of NMDA receptors and postsynaptic events",8,114,0.007769372316499694,0.161998083819884,0.323996167639768,5,71,0.005477549760839377,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B;KPNA2","","R-HSA-9610627;R-HSA-9619542;R-HSA-9619127;R-HSA-9610408;R-HSA-112282" R-HSA-6783589,"Interleukin-6 family signaling",3,30,0.0020445716622367613,0.1630308700978389,0.3260617401956778,18,33,0.0025459034099675976,9606,Homo sapiens,"IL11;IL6R","","R-HSA-1112690;R-HSA-1112755;R-HSA-1067667;R-HSA-449829;R-HSA-1112565;R-HSA-1112727;R-HSA-1067640;R-HSA-1112602;R-HSA-1112604;R-HSA-1067676;R-HSA-1112510;R-HSA-1112703;R-HSA-1112514;R-HSA-1067651;R-HSA-1112708;R-HSA-1067688;R-HSA-1067659;R-HSA-449976" R-HSA-1566948,"Elastic fibre formation",4,46,0.0031350098820963675,0.1659473632839943,0.3318947265679886,6,17,0.001311525999074217,9606,Homo sapiens,"BMP2;LOXL3;EMILIN2;LTBP1","","R-HSA-2161282;R-HSA-2328033;R-HSA-2328048;R-HSA-2395328;R-HSA-2396399;R-HSA-2129375" R-HSA-8854521,"Interaction between PHLDA1 and AURKA",1,4,2.726095549649015E-4,0.16877476169362193,0.33754952338724387,2,2,1.5429717636167257E-4,9606,Homo sapiens,"AURKB;AURKA","","R-HSA-8853429;R-HSA-8853444" R-HSA-5655799,"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)",1,4,2.726095549649015E-4,0.16877476169362193,0.33754952338724387,1,1,7.714858818083629E-5,9606,Homo sapiens,"SLC40A1","","R-HSA-5655760" R-HSA-5619049,"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)",1,4,2.726095549649015E-4,0.16877476169362193,0.33754952338724387,1,1,7.714858818083629E-5,9606,Homo sapiens,"SLC40A1","","R-HSA-5655733" R-HSA-1059683,"Interleukin-6 signaling",2,17,0.0011585906086008315,0.1859695381050268,0.3719390762100536,16,19,0.0014658231754358896,9606,Homo sapiens,"IL6R","","R-HSA-1112690;R-HSA-1112755;R-HSA-1067667;R-HSA-1112565;R-HSA-1112727;R-HSA-1067640;R-HSA-1112602;R-HSA-1112604;R-HSA-1067676;R-HSA-1112510;R-HSA-1112703;R-HSA-1112514;R-HSA-1067651;R-HSA-1112708;R-HSA-1067688;R-HSA-1067659" R-HSA-5676594,"TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway",2,17,0.0011585906086008315,0.1859695381050268,0.3719390762100536,6,12,9.257830581700355E-4,9606,Homo sapiens,"CD40;BIRC3","","R-HSA-5676598;R-HSA-5676596;R-HSA-5676597;R-HSA-5676595;R-HSA-5676593;R-HSA-199404" R-HSA-73857,"RNA Polymerase II Transcription",86,1693,0.11538199413889456,0.1900110507580438,0.3800221015160876,96,885,0.06827650054004011,9606,Homo sapiens,"SERPINE1;BRCA1;EXO1;HIST1H2AE;HIST1H2AD;MYBL2;RFC3;RFC4;H2AFZ;RFC2;HIST1H2AK;H2AFX;HIST2H2BB;CDC25C;CCNA2;RBL1;CCNE2;FANCD2;GPRIN1;ZNF724P;RRAGD;HIST1H2BF;BIRC5;HIST1H2BE;HIST1H2BG;HIST1H2BB;SCG2;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;TCF7;HIST1H2BK;AURKB;AURKA;HIST2H4A;BRIP1;CCNB1;BCL2L11;E2F1;HIST1H3B;E2F7;MAP2K6;E2F8;FANCI;RRM2;ABCA6;UBE2C;HIST1H4L;ATAD2;NR0B1;CDC7;H2BFS;SOD2;TPX2;OCLN;BMP2;RAD51;HIST1H4B;UBE2S;CENPJ;CDK2;CDK1;HIST1H4H;HIST1H4C;ZNF730;HIST1H4D;HIST1H4E;ZNF530;EZH2","","R-HSA-8936584;R-HSA-8937097;R-HSA-9007496;R-HSA-6799332;R-HSA-6798304;R-HSA-6805103;R-HSA-3790130;R-HSA-9009282;R-HSA-8951428;R-HSA-8937113;R-HSA-8937369;R-HSA-9625091;R-HSA-6805109;R-HSA-9007514;R-HSA-382096;R-HSA-8936989;R-HSA-9023132;R-HSA-9625092;R-HSA-8937118;R-HSA-8936979;R-HSA-187934;R-HSA-8936599;R-HSA-8952232;R-HSA-8936616;R-HSA-9622579;R-HSA-6797766;R-HSA-6791235;R-HSA-6797763;R-HSA-8935980;R-HSA-8936621;R-HSA-9617972;R-HSA-8936608;R-HSA-8936481;R-HSA-8952226;R-HSA-8869549;R-HSA-8936995;R-HSA-8952996;R-HSA-6798282;R-HSA-8937016;R-HSA-2186643;R-HSA-9007546;R-HSA-8935740;R-HSA-380979;R-HSA-8937022;R-HSA-8961982;R-HSA-8869566;R-HSA-2127257;R-HSA-8935730;R-HSA-9617832;R-HSA-9617833;R-HSA-8935731;R-HSA-69562;R-HSA-8935988;R-HSA-8936628;R-HSA-6798299;R-HSA-8953013;R-HSA-9622572;R-HSA-9007561;R-HSA-6797606;R-HSA-6803875;R-HSA-8937037;R-HSA-8953037;R-HSA-9008832;R-HSA-975040;R-HSA-9007707;R-HSA-8937050;R-HSA-8865491;R-HSA-1484099;R-HSA-9007582;R-HSA-6797616;R-HSA-6793661;R-HSA-6798268;R-HSA-8953556;R-HSA-8865498;R-HSA-9622604;R-HSA-6805126;R-HSA-9007467;R-HSA-8953452;R-HSA-6805122;R-HSA-6801666;R-HSA-376419;R-HSA-8865505;R-HSA-6798347;R-HSA-9007591;R-HSA-9007462;R-HSA-9021946;R-HSA-9021948;R-HSA-6798353;R-HSA-8954110;R-HSA-6797712;R-HSA-2106586;R-HSA-6802973;R-HSA-8877691;R-HSA-9007605;R-HSA-9007220;R-HSA-9007606" R-HSA-3214841,"PKMTs methylate histone lysines",4,49,0.0033394670483200438,0.1931587556672355,0.386317511334471,20,22,0.0016972689399783983,9606,Homo sapiens,"HIST2H4A;HIST1H4B;HIST1H3J;HIST1H4L;SUV39H1;HIST1H4H;HIST1H4C;HIST1H3B;HIST1H4D;HIST1H4E;EZH2","","R-HSA-5637686;R-HSA-5159245;R-HSA-5244692;R-HSA-5634802;R-HSA-5638332;R-HSA-5634750;R-HSA-5638333;R-HSA-5638141;R-HSA-5423038;R-HSA-5651654;R-HSA-5649799;R-HSA-5649764;R-HSA-5638157;R-HSA-5634729;R-HSA-5649802;R-HSA-5649800;R-HSA-4827383;R-HSA-4827382;R-HSA-5649801;R-HSA-5651657" R-HSA-9615017,"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes",4,49,0.0033394670483200438,0.1931587556672355,0.386317511334471,5,34,0.002623051998148434,9606,Homo sapiens,"ABCA6;SOD2","","R-HSA-9625091;R-HSA-9625092;R-HSA-9617972;R-HSA-9617832;R-HSA-9617833" R-HSA-8866652,"Synthesis of active ubiquitin: roles of E1 and E2 enzymes",3,33,0.0022490288284604375,0.19727867963453316,0.3945573592690663,3,16,0.0012343774108933806,9606,Homo sapiens,"UBE2S;UBE2C;UBE2T","","R-HSA-8852130;R-HSA-8852129;R-HSA-8852127" R-HSA-111446,"Activation of BIM and translocation to mitochondria ",1,5,3.407619437061269E-4,0.2063208328692474,0.4126416657384948,2,2,1.5429717636167257E-4,9606,Homo sapiens,"BCL2L11","","R-HSA-139918;R-HSA-139919" R-HSA-139910,"Activation of BMF and translocation to mitochondria",1,5,3.407619437061269E-4,0.2063208328692474,0.4126416657384948,2,2,1.5429717636167257E-4,9606,Homo sapiens,"BMF","","R-HSA-139908;R-HSA-139909" R-HSA-1368071,"NR1D1 (REV-ERBA) represses gene expression",1,5,3.407619437061269E-4,0.2063208328692474,0.4126416657384948,1,1,7.714858818083629E-5,9606,Homo sapiens,"ELOVL3","","R-HSA-5663252" R-HSA-1483076,"Synthesis of CL",1,5,3.407619437061269E-4,0.2063208328692474,0.4126416657384948,1,1,7.714858818083629E-5,9606,Homo sapiens,"MCM8","","R-HSA-1483063" R-HSA-380095,"Tachykinin receptors bind tachykinins",1,5,3.407619437061269E-4,0.2063208328692474,0.4126416657384948,1,3,2.3144576454250888E-4,9606,Homo sapiens,"TACR2","","R-HSA-383363" R-HSA-171319,"Telomere Extension By Telomerase",3,34,0.002317181217201663,0.20905973852353488,0.41811947704706975,8,10,7.714858818083629E-4,9606,Homo sapiens,"CCNA2;CDK2;CDK1;WRAP53","","R-HSA-163090;R-HSA-163120;R-HSA-163099;R-HSA-163096;R-HSA-9686521;R-HSA-164616;R-HSA-164617;R-HSA-164620" R-HSA-5610787,"Hedgehog 'off' state",8,124,0.008450896203911947,0.21901351191943796,0.43802702383887593,11,32,0.002468754821786761,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;GLI1;TUBB4B","","R-HSA-5610741;R-HSA-5617412;R-HSA-5610758;R-HSA-5610742;R-HSA-5610737;R-HSA-5617408;R-HSA-5610723;R-HSA-5610733;R-HSA-5610767;R-HSA-5610766;R-HSA-5610760" R-HSA-416700,"Other semaphorin interactions",2,19,0.0012948953860832822,0.21942705090977055,0.4388541018195411,2,9,6.943372936275266E-4,9606,Homo sapiens,"CD72;PLXNC1","","R-HSA-373748;R-HSA-434989" R-HSA-6807878,"COPI-mediated anterograde transport",7,107,0.007292305595311115,0.22914111040576102,0.45828222081152203,2,12,9.257830581700355E-4,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-6809006;R-HSA-6809003" R-HSA-114452,"Activation of BH3-only proteins",3,36,0.0024534859946841138,0.23305590460119974,0.4661118092023995,8,19,0.0014658231754358896,9606,Homo sapiens,"BCL2L11;E2F1;BMF","","R-HSA-139908;R-HSA-139909;R-HSA-140217;R-HSA-139918;R-HSA-139919;R-HSA-4331327;R-HSA-4331324;R-HSA-140221" R-HSA-9687136,"Aberrant regulation of mitotic exit in cancer due to RB1 defects",2,20,0.0013630477748245075,0.23634489127472313,0.47268978254944627,1,1,7.714858818083629E-5,9606,Homo sapiens,"UBE2S;UBE2C","","R-HSA-9687377" R-HSA-5619060,"Defective CP causes aceruloplasminemia (ACERULOP)",1,6,4.089143324473523E-4,0.24217335298348885,0.4843467059669777,1,1,7.714858818083629E-5,9606,Homo sapiens,"SLC40A1","","R-HSA-5621402" R-HSA-140834,"Extrinsic Pathway of Fibrin Clot Formation",1,6,4.089143324473523E-4,0.24217335298348885,0.4843467059669777,7,8,6.171887054466903E-4,9606,Homo sapiens,"F3","","R-HSA-140736;R-HSA-140823;R-HSA-140825;R-HSA-140777;R-HSA-140761;R-HSA-140783;R-HSA-140748" R-HSA-2408552,"Methylation of MeSeH for excretion",1,6,4.089143324473523E-4,0.24217335298348885,0.4843467059669777,1,2,1.5429717636167257E-4,9606,Homo sapiens,"INMT","","R-HSA-2408554" R-HSA-111448,"Activation of NOXA and translocation to mitochondria",1,6,4.089143324473523E-4,0.24217335298348885,0.4843467059669777,2,5,3.8574294090418145E-4,9606,Homo sapiens,"E2F1","","R-HSA-140217;R-HSA-4331327" R-HSA-140877,"Formation of Fibrin Clot (Clotting Cascade)",4,55,0.0037483813807673958,0.2511237407433742,0.5022474814867484,15,61,0.004706063879031014,9606,Homo sapiens,"THBD;TG;SERPING1;F3","","R-HSA-140736;R-HSA-140777;R-HSA-140847;R-HSA-140783;R-HSA-140748;R-HSA-140851;R-HSA-141040;R-HSA-141046;R-HSA-140599;R-HSA-140823;R-HSA-158357;R-HSA-9650473;R-HSA-140825;R-HSA-140761;R-HSA-158399" R-HSA-2173793,"Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer",4,55,0.0037483813807673958,0.2511237407433742,0.5022474814867484,4,38,0.002931646350871779,9606,Homo sapiens,"RBL1;SERPINE1;SCG2","","R-HSA-2186643;R-HSA-1484099;R-HSA-2127257;R-HSA-2106586" R-HSA-1483148,"Synthesis of PG",2,21,0.0014312001635657329,0.25332860466179175,0.5066572093235835,1,5,3.8574294090418145E-4,9606,Homo sapiens,"PLD1","","R-HSA-1483142" R-HSA-2129379,"Molecules associated with elastic fibres",3,38,0.0025897907721665644,0.2575105597768561,0.5150211195537122,5,10,7.714858818083629E-4,9606,Homo sapiens,"BMP2;EMILIN2;LTBP1","","R-HSA-2161282;R-HSA-2328033;R-HSA-2328048;R-HSA-2395328;R-HSA-2396399" R-HSA-111465,"Apoptotic cleavage of cellular proteins",3,38,0.0025897907721665644,0.2575105597768561,0.5150211195537122,3,38,0.002931646350871779,9606,Homo sapiens,"OCLN;CLSPN;LMNB1","","R-HSA-351876;R-HSA-264871;R-HSA-351936" R-HSA-174437,"Removal of the Flap Intermediate from the C-strand",2,22,0.0014993525523069584,0.27033780809029917,0.5227527106656185,4,4,3.0859435272334514E-4,9606,Homo sapiens,"FEN1;POLD1","","R-HSA-174451;R-HSA-174441;R-HSA-174446;R-HSA-174445" R-HSA-174430,"Telomere C-strand synthesis initiation",2,22,0.0014993525523069584,0.27033780809029917,0.5227527106656185,3,4,3.0859435272334514E-4,9606,Homo sapiens,"POLA2;PRIM1","","R-HSA-9668597;R-HSA-174427;R-HSA-174425" R-HSA-390522,"Striated Muscle Contraction",3,40,0.002726095549649015,0.28228671504169633,0.5227527106656185,4,4,3.0859435272334514E-4,9606,Homo sapiens,"ACTC1;TNNC2;NEB","","R-HSA-390597;R-HSA-390598;R-HSA-390593;R-HSA-390595" R-HSA-1482788,"Acyl chain remodelling of PC",3,40,0.002726095549649015,0.28228671504169633,0.5227527106656185,4,9,6.943372936275266E-4,9606,Homo sapiens,"TMEM86A;CFI;NES","","R-HSA-1482533;R-HSA-8874435;R-HSA-1482547;R-HSA-1602417" R-HSA-168638,"NOD1/2 Signaling Pathway",3,40,0.002726095549649015,0.28228671504169633,0.5227527106656185,4,18,0.0013886745872550533,9606,Homo sapiens,"TNFAIP3;BIRC3;MAP2K6","","R-HSA-727819;R-HSA-688136;R-HSA-688137;R-HSA-1247960" R-HSA-2564830,"Cytosolic iron-sulfur cluster assembly",2,23,0.0015675049410481838,0.28733562135290613,0.5227527106656185,1,3,2.3144576454250888E-4,9606,Homo sapiens,"BRIP1;POLD1","","R-HSA-2564828" R-HSA-9614657,"FOXO-mediated transcription of cell death genes",2,23,0.0015675049410481838,0.28733562135290613,0.5227527106656185,3,15,0.0011572288227125443,9606,Homo sapiens,"BCL2L11","","R-HSA-9622579;R-HSA-9622604;R-HSA-9622572" R-HSA-5625900,"RHO GTPases activate CIT",2,23,0.0015675049410481838,0.28733562135290613,0.5227527106656185,1,6,4.6289152908501776E-4,9606,Homo sapiens,"PRC1;KIF14;NEB","","R-HSA-5671970" R-HSA-937041,"IKK complex recruitment mediated by RIP1",2,24,0.001635657329789409,0.3042884337876286,0.5227527106656185,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CD14;BIRC3","","R-HSA-168915;R-HSA-937029;R-HSA-168921" R-HSA-3301854,"Nuclear Pore Complex (NPC) Disassembly",3,42,0.0028624003271314658,0.3072564107735154,0.5227527106656185,1,2,1.5429717636167257E-4,9606,Homo sapiens,"CCNB2;CCNB1;CDK1","","R-HSA-2990882" R-HSA-2559585,"Oncogene Induced Senescence",3,42,0.0028624003271314658,0.3072564107735154,0.5227527106656185,3,19,0.0014658231754358896,9606,Homo sapiens,"CDKN2D;E2F1","","R-HSA-182594;R-HSA-3209109;R-HSA-3209096" R-HSA-8849470,"PTK6 Regulates Cell Cycle",1,8,5.45219109929803E-4,0.3090994349425612,0.5227527106656185,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CDK2","","R-HSA-8848436;R-HSA-8848414" R-HSA-9652817,"Signaling by MAPK mutants",1,8,5.45219109929803E-4,0.3090994349425612,0.5227527106656185,1,1,7.714858818083629E-5,9606,Homo sapiens,"POC1A","","R-HSA-9652816" R-HSA-5576894,"Phase 1 - inactivation of fast Na+ channels",1,8,5.45219109929803E-4,0.3090994349425612,0.5227527106656185,1,1,7.714858818083629E-5,9606,Homo sapiens,"KCND3","","R-HSA-5577234" R-HSA-9605308,"Diseases of Base Excision Repair",1,8,5.45219109929803E-4,0.3090994349425612,0.5227527106656185,1,19,0.0014658231754358896,9606,Homo sapiens,"NEIL3","","R-HSA-9629245" R-HSA-198725,"Nuclear Events (kinase and transcription factor activation)",5,80,0.00545219109929803,0.3119606903343235,0.5227527106656185,4,47,0.0036259836444993056,9606,Homo sapiens,"DUSP4;FOSL1;POC1A;F3","","R-HSA-9621042;R-HSA-9031624;R-HSA-203797;R-HSA-9621035" R-HSA-5696398,"Nucleotide Excision Repair",7,119,0.00811013426020582,0.3134329659999492,0.5227527106656185,8,37,0.0028544977626909426,9606,Homo sapiens,"RFC3;RFC4;LIG1;RFC2;POLE2;POLD1","","R-HSA-5690213;R-HSA-5690997;R-HSA-6782227;R-HSA-6782211;R-HSA-6782208;R-HSA-6782224;R-HSA-5690988;R-HSA-5691001" R-HSA-6804757,"Regulation of TP53 Degradation",3,43,0.0029305527158726913,0.3197764436688657,0.5227527106656185,1,30,0.0023144576454250886,9606,Homo sapiens,"CCNA2;CDK2;CDK1","","R-HSA-6793661" R-HSA-5654221,"Phospholipase C-mediated cascade; FGFR2",2,25,0.0017038097185306344,0.32116568492043385,0.5227527106656185,3,3,2.3144576454250888E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654147;R-HSA-5654159;R-HSA-5654157" R-HSA-162594,"Early Phase of HIV Life Cycle",2,25,0.0017038097185306344,0.32116568492043385,0.5227527106656185,1,38,0.002931646350871779,9606,Homo sapiens,"FEN1;LIG1","","R-HSA-182876" R-HSA-187577,"SCF(Skp2)-mediated degradation of p27/p21",4,62,0.004225448101955974,0.32245679797593896,0.5227527106656185,7,7,5.40040117265854E-4,9606,Homo sapiens,"CCNA2;CCNE2;CDK2;CDK1;CKS1B","","R-HSA-187552;R-HSA-187520;R-HSA-8848436;R-HSA-187574;R-HSA-187575;R-HSA-8848414;R-HSA-187545" R-HSA-190241,"FGFR2 ligand binding and activation",2,26,0.0017719621072718598,0.3379396582066462,0.5227527106656185,5,5,3.8574294090418145E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5656070;R-HSA-190258;R-HSA-190260;R-HSA-190408;R-HSA-190413" R-HSA-1482925,"Acyl chain remodelling of PG",2,26,0.0017719621072718598,0.3379396582066462,0.5227527106656185,3,10,7.714858818083629E-4,9606,Homo sapiens,"MCM8;CFI","","R-HSA-1482546;R-HSA-1482689;R-HSA-1602368" R-HSA-210991,"Basigin interactions",2,26,0.0017719621072718598,0.3379396582066462,0.5227527106656185,2,10,7.714858818083629E-4,9606,Homo sapiens,"SLC7A5;MMP1","","R-HSA-375135;R-HSA-375131" R-HSA-198753,"ERK/MAPK targets",2,26,0.0017719621072718598,0.3379396582066462,0.5227527106656185,1,7,5.40040117265854E-4,9606,Homo sapiens,"DUSP4;POC1A","","R-HSA-203797" R-HSA-164944,"Nef and signal transduction",1,9,6.133714986710284E-4,0.34031542074297627,0.5227527106656185,1,5,3.8574294090418145E-4,9606,Homo sapiens,"DOCK2","","R-HSA-200952" R-HSA-3108232,"SUMO E3 ligases SUMOylate target proteins",10,183,0.012471887139644245,0.3408665432334773,0.5227527106656185,11,131,0.010106465051689554,9606,Homo sapiens,"TOP2A;BLM;HIST1H4L;CDCA8;MITF;BRCA1;AURKB;AURKA;HIST2H4A;HIST1H4B;INCENP;BIRC5;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E","","R-HSA-4570485;R-HSA-4641350;R-HSA-2997709;R-HSA-5228525;R-HSA-3232162;R-HSA-4570496;R-HSA-4568914;R-HSA-4641342;R-HSA-4655404;R-HSA-4655355;R-HSA-2997616" R-HSA-194840,"Rho GTPase cycle",8,144,0.009813943978736455,0.3496059630685995,0.5227527106656185,2,5,3.8574294090418145E-4,9606,Homo sapiens,"ARHGAP11A;DEPDC1B;ARHGAP20;RACGAP1;ARHGEF3;ARHGAP18;ARHGAP28;ECT2","","R-HSA-194913;R-HSA-194922" R-HSA-6806003,"Regulation of TP53 Expression and Degradation",3,46,0.0031350098820963675,0.3573124251053291,0.5227527106656185,1,35,0.00270020058632927,9606,Homo sapiens,"CCNA2;CDK2;CDK1","","R-HSA-6793661" R-HSA-74160,"Gene expression (Transcription)",89,1851,0.12615007156000818,0.3608384527478061,0.5227527106656185,120,996,0.07683999382811295,9606,Homo sapiens,"SUV39H1;SERPINE1;BRCA1;EXO1;HIST1H2AE;HIST1H2AD;MYBL2;MYBL1;RFC3;RFC4;H2AFZ;RFC2;HIST1H2AK;H2AFX;HIST2H2BB;CDC25C;CCNA2;RBL1;CCNE2;FANCD2;GPRIN1;ZNF724P;RRAGD;HIST1H2BF;BIRC5;HIST1H2BE;HIST1H2BG;HIST1H2BB;SCG2;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H3J;HIST1H2BJ;UHRF1;HIST1H2BI;HIST1H2BL;TCF7;HIST1H2BK;AURKB;AURKA;HIST2H4A;BRIP1;CCNB1;BCL2L11;E2F1;HIST1H3B;E2F7;MAP2K6;E2F8;FANCI;RRM2;ABCA6;UBE2C;HIST1H4L;ATAD2;NR0B1;CDC7;H2BFS;SOD2;TPX2;OCLN;BMP2;RAD51;HIST1H4B;UBE2S;CENPJ;CDK2;CDK1;HIST1H4H;HIST1H4C;ZNF730;HIST1H4D;HIST1H4E;ZNF530;EZH2","","R-HSA-8936584;R-HSA-5334097;R-HSA-8937097;R-HSA-427527;R-HSA-9007496;R-HSA-5334099;R-HSA-6805103;R-HSA-3790130;R-HSA-9009282;R-HSA-8951428;R-HSA-433672;R-HSA-427528;R-HSA-8937113;R-HSA-8937369;R-HSA-6805109;R-HSA-9007514;R-HSA-9023132;R-HSA-8937118;R-HSA-187934;R-HSA-8936599;R-HSA-212252;R-HSA-8952232;R-HSA-8936616;R-HSA-212263;R-HSA-6791235;R-HSA-8936621;R-HSA-8936608;R-HSA-5250938;R-HSA-8952226;R-HSA-8869549;R-HSA-8952996;R-HSA-212269;R-HSA-9007546;R-HSA-380979;R-HSA-8961982;R-HSA-8869566;R-HSA-9617832;R-HSA-9617833;R-HSA-8936628;R-HSA-8953013;R-HSA-9007561;R-HSA-6797606;R-HSA-8953037;R-HSA-9008832;R-HSA-427336;R-HSA-427337;R-HSA-8865491;R-HSA-1484099;R-HSA-9007582;R-HSA-6797616;R-HSA-8953556;R-HSA-8865498;R-HSA-6801666;R-HSA-376419;R-HSA-8865505;R-HSA-6798347;R-HSA-9007591;R-HSA-427383;R-HSA-9021946;R-HSA-9021948;R-HSA-6798353;R-HSA-8954110;R-HSA-6802973;R-HSA-9007605;R-HSA-9007606;R-HSA-6799332;R-HSA-6798304;R-HSA-9625091;R-HSA-382096;R-HSA-8936989;R-HSA-9625092;R-HSA-8936979;R-HSA-9622579;R-HSA-6797766;R-HSA-5578742;R-HSA-6797763;R-HSA-8935980;R-HSA-9617972;R-HSA-8936481;R-HSA-8936995;R-HSA-5227490;R-HSA-6798282;R-HSA-8937016;R-HSA-2186643;R-HSA-8935740;R-HSA-8937022;R-HSA-2127257;R-HSA-8935730;R-HSA-8935731;R-HSA-69562;R-HSA-8935988;R-HSA-6798299;R-HSA-9622572;R-HSA-5334160;R-HSA-6803875;R-HSA-8937037;R-HSA-5334164;R-HSA-975040;R-HSA-9007707;R-HSA-8937050;R-HSA-5601926;R-HSA-5334151;R-HSA-5334152;R-HSA-6793661;R-HSA-6798268;R-HSA-9622604;R-HSA-6805126;R-HSA-9007467;R-HSA-8953452;R-HSA-6805122;R-HSA-74986;R-HSA-9007462;R-HSA-5334179;R-HSA-73718;R-HSA-6797712;R-HSA-2106586;R-HSA-8877691;R-HSA-427514;R-HSA-212222;R-HSA-9007220" R-HSA-2562578,"TRIF-mediated programmed cell death",1,10,6.815238874122538E-4,0.3701230046923415,0.5227527106656185,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CD14","","R-HSA-2562564;R-HSA-2569057;R-HSA-2562541" R-HSA-964827,"Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2",1,10,6.815238874122538E-4,0.3701230046923415,0.5227527106656185,3,3,2.3144576454250888E-4,9606,Homo sapiens,"MAN1C1","","R-HSA-964830;R-HSA-964825;R-HSA-964737" R-HSA-4411364,"Binding of TCF/LEF:CTNNB1 to target gene promoters",1,10,6.815238874122538E-4,0.3701230046923415,0.5227527106656185,2,4,3.0859435272334514E-4,9606,Homo sapiens,"TCF7","","R-HSA-4411351;R-HSA-4411372" R-HSA-139915,"Activation of PUMA and translocation to mitochondria",1,10,6.815238874122538E-4,0.3701230046923415,0.5227527106656185,2,5,3.8574294090418145E-4,9606,Homo sapiens,"E2F1","","R-HSA-4331324;R-HSA-140221" R-HSA-8964046,"VLDL clearance",1,10,6.815238874122538E-4,0.3701230046923415,0.5227527106656185,1,3,2.3144576454250888E-4,9606,Homo sapiens,"LSR","","R-HSA-8933292" R-HSA-8951430,"RUNX3 regulates WNT signaling",1,10,6.815238874122538E-4,0.3701230046923415,0.5227527106656185,1,5,3.8574294090418145E-4,9606,Homo sapiens,"TCF7","","R-HSA-8951428" R-HSA-6804115,"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain",2,28,0.0019082668847543107,0.37107997300939455,0.5227527106656185,2,14,0.001080080234531708,9606,Homo sapiens,"CENPJ;CDC25C","","R-HSA-6801666;R-HSA-6802973" R-HSA-6803205,"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain",2,28,0.0019082668847543107,0.37107997300939455,0.5227527106656185,2,19,0.0014658231754358896,9606,Homo sapiens,"BIRC5","","R-HSA-6797766;R-HSA-6797763" R-HSA-174154,"APC/C:Cdc20 mediated degradation of Securin",4,68,0.004634362434403326,0.3846424884763222,0.5227527106656185,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CDC20;PTTG1;UBE2S;UBE2C","","R-HSA-174144;R-HSA-174202;R-HSA-174121" R-HSA-8873719,"RAB geranylgeranylation",4,68,0.004634362434403326,0.3846424884763222,0.5227527106656185,2,5,3.8574294090418145E-4,9606,Homo sapiens,"RAB20;CDK2;RAB27B;RAB33A","","R-HSA-8870469;R-HSA-8870466" R-HSA-2033519,"Activated point mutants of FGFR2",2,29,0.001976419273495536,0.38740341373064324,0.5227527106656185,6,10,7.714858818083629E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-2033486;R-HSA-2077421;R-HSA-2033474;R-HSA-2077424;R-HSA-2033472;R-HSA-2033488" R-HSA-1369062,"ABC transporters in lipid homeostasis",2,29,0.001976419273495536,0.38740341373064324,0.5227527106656185,2,11,8.486344699891992E-4,9606,Homo sapiens,"ABCA6;ABCA8","","R-HSA-1369028;R-HSA-1369052" R-HSA-1632852,"Macroautophagy",8,150,0.010222858311183807,0.39096654257833385,0.5227527106656185,9,87,0.006711927171732758,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;RRAGD;TUBB4B","","R-HSA-9646679;R-HSA-9646390;R-HSA-5672017;R-HSA-5672817;R-HSA-5675790;R-HSA-5672010;R-HSA-9646383;R-HSA-5673768;R-HSA-9646685" R-HSA-2990846,"SUMOylation",10,192,0.013085258638315273,0.3955931312036318,0.5227527106656185,11,140,0.01080080234531708,9606,Homo sapiens,"TOP2A;BLM;HIST1H4L;CDCA8;MITF;BRCA1;AURKB;AURKA;HIST2H4A;HIST1H4B;INCENP;BIRC5;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E","","R-HSA-4570485;R-HSA-4641350;R-HSA-2997709;R-HSA-5228525;R-HSA-3232162;R-HSA-4570496;R-HSA-4568914;R-HSA-4641342;R-HSA-4655404;R-HSA-4655355;R-HSA-2997616" R-HSA-212718,"EGFR interacts with phospholipase C-gamma",1,11,7.496762761534792E-4,0.3985856414037411,0.5227527106656185,3,3,2.3144576454250888E-4,9606,Homo sapiens,"BTC","","R-HSA-212706;R-HSA-212710;R-HSA-212713" R-HSA-9012546,"Interleukin-18 signaling",1,11,7.496762761534792E-4,0.3985856414037411,0.5227527106656185,2,4,3.0859435272334514E-4,9606,Homo sapiens,"IL18R1","","R-HSA-8848370;R-HSA-8848395" R-HSA-446205,"Synthesis of GDP-mannose",1,11,7.496762761534792E-4,0.3985856414037411,0.5227527106656185,1,3,2.3144576454250888E-4,9606,Homo sapiens,"GMPPB","","R-HSA-446221" R-HSA-442729,"CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde",1,11,7.496762761534792E-4,0.3985856414037411,0.5227527106656185,2,10,7.714858818083629E-4,9606,Homo sapiens,"KPNA2","","R-HSA-9619127;R-HSA-112282" R-HSA-351906,"Apoptotic cleavage of cell adhesion proteins",1,11,7.496762761534792E-4,0.3985856414037411,0.5227527106656185,1,10,7.714858818083629E-4,9606,Homo sapiens,"OCLN","","R-HSA-351876" R-HSA-9614085,"FOXO-mediated transcription",6,110,0.0074967627615347915,0.3986195734115956,0.5227527106656185,8,85,0.006557629995371085,9606,Homo sapiens,"BCL2L11;ABCA6;SOD2","","R-HSA-9625091;R-HSA-9622579;R-HSA-9625092;R-HSA-9617972;R-HSA-9617832;R-HSA-9617833;R-HSA-9622604;R-HSA-9622572" R-HSA-5357956,"TNFR1-induced NFkappaB signaling pathway",2,30,0.0020445716622367613,0.403537442991325,0.5227527106656185,5,5,3.8574294090418145E-4,9606,Homo sapiens,"TNFAIP3;BIRC3","","R-HSA-5357776;R-HSA-5357904;R-HSA-5357860;R-HSA-5357780;R-HSA-5357757" R-HSA-3214842,"HDMs demethylate histones",2,31,0.002112724050977987,0.4194658792629553,0.5227527106656185,17,17,0.001311525999074217,9606,Homo sapiens,"HIST2H4A;HIST1H4B;HIST1H3J;HIST1H4L;HIST1H4H;HIST1H4C;HIST1H3B;HIST1H4D;HIST1H4E","","R-HSA-4754187;R-HSA-4754176;R-HSA-5661116;R-HSA-5661114;R-HSA-5661115;R-HSA-4754181;R-HSA-3214912;R-HSA-5661124;R-HSA-5661125;R-HSA-4724284;R-HSA-5661122;R-HSA-5661123;R-HSA-5661120;R-HSA-5661121;R-HSA-4722133;R-HSA-4724279;R-HSA-5423117" R-HSA-5654695,"PI-3K cascade:FGFR2",2,31,0.002112724050977987,0.4194658792629553,0.5227527106656185,6,7,5.40040117265854E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654614;R-HSA-5654612;R-HSA-5654622;R-HSA-5654620;R-HSA-5654701;R-HSA-5654697" R-HSA-1482801,"Acyl chain remodelling of PS",2,31,0.002112724050977987,0.4194658792629553,0.5227527106656185,3,8,6.171887054466903E-4,9606,Homo sapiens,"CFI;NES","","R-HSA-1482691;R-HSA-1482636;R-HSA-1602374" R-HSA-1266695,"Interleukin-7 signaling",2,31,0.002112724050977987,0.4194658792629553,0.5227527106656185,2,25,0.0019287147045209073,9606,Homo sapiens,"HIST1H3J;HIST1H3B;HIST1H3C","","R-HSA-8865711;R-HSA-8865613" R-HSA-2534343,"Interaction With Cumulus Cells And The Zona Pellucida",1,12,8.178286648947046E-4,0.4257639306227886,0.5227527106656185,1,2,1.5429717636167257E-4,9606,Homo sapiens,"OVGP1","","R-HSA-1297338" R-HSA-418889,"Caspase activation via Dependence Receptors in the absence of ligand",1,12,8.178286648947046E-4,0.4257639306227886,0.5227527106656185,1,8,6.171887054466903E-4,9606,Homo sapiens,"DAPK2","","R-HSA-418849" R-HSA-69615,"G1/S DNA Damage Checkpoints",4,72,0.0049069719893682275,0.42577980636773805,0.5227527106656185,6,26,0.0020058632927017436,9606,Homo sapiens,"CCNA2;CCNE2;CDK2;CDC25A","","R-HSA-69600;R-HSA-69604;R-HSA-69608;R-HSA-69562;R-HSA-187934;R-HSA-69598" R-HSA-8864260,"Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors",3,52,0.0035439242145437195,0.43120420163890305,0.5227527106656185,3,44,0.0033945378799567967,9606,Homo sapiens,"ATAD2;MYBL2","","R-HSA-8937369;R-HSA-8869566;R-HSA-8869549" R-HSA-70635,"Urea cycle",2,32,0.002180876439719212,0.43517438403867925,0.5227527106656185,2,8,6.171887054466903E-4,9606,Homo sapiens,"ORC1;NAGS","","R-HSA-70634;R-HSA-70542" R-HSA-525793,"Myogenesis",2,32,0.002180876439719212,0.43517438403867925,0.5227527106656185,3,14,0.001080080234531708,9606,Homo sapiens,"MYF6;MAP2K6","","R-HSA-448951;R-HSA-448962;R-HSA-448963" R-HSA-5357769,"Caspase activation via extrinsic apoptotic signalling pathway",2,32,0.002180876439719212,0.43517438403867925,0.5227527106656185,2,17,0.001311525999074217,9606,Homo sapiens,"DAPK2;CD14","","R-HSA-2562564;R-HSA-418849" R-HSA-9022699,"MECP2 regulates neuronal receptors and channels",2,32,0.002180876439719212,0.43517438403867925,0.5227527106656185,2,26,0.0020058632927017436,9606,Homo sapiens,"GPRIN1","","R-HSA-9021946;R-HSA-9021948" R-HSA-913709,"O-linked glycosylation of mucins",4,73,0.004975124378109453,0.43596442173718764,0.5227527106656185,3,17,0.001311525999074217,9606,Homo sapiens,"GALNT15;GALNT18;GCNT3","","R-HSA-914012;R-HSA-913675;R-HSA-914018" R-HSA-8950505,"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation",4,73,0.004975124378109453,0.43596442173718764,0.5227527106656185,2,36,0.0027773491745101066,9606,Homo sapiens,"SOD2;LMNB1","","R-HSA-8950681;R-HSA-9617941" R-HSA-114608,"Platelet degranulation ",7,137,0.009336877257547877,0.4468575201489038,0.5227527106656185,3,11,8.486344699891992E-4,9606,Homo sapiens,"CLEC3B;TG;SERPINE1;SERPING1;EMILIN2;RAB27B;SEPP1","","R-HSA-481010;R-HSA-481009;R-HSA-481007" R-HSA-5654699,"SHC-mediated cascade:FGFR2",2,33,0.0022490288284604375,0.4506503288022127,0.5227527106656185,4,4,3.0859435272334514E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654406;R-HSA-5654407;R-HSA-5654404;R-HSA-5654402" R-HSA-390666,"Serotonin receptors",1,13,8.859810536359299E-4,0.4517157454885806,0.5227527106656185,1,3,2.3144576454250888E-4,9606,Homo sapiens,"HTR2B","","R-HSA-390930" R-HSA-111932,"CaMK IV-mediated phosphorylation of CREB",1,13,8.859810536359299E-4,0.4517157454885806,0.5227527106656185,2,13,0.0010029316463508718,9606,Homo sapiens,"KPNA2","","R-HSA-9619127;R-HSA-112282" R-HSA-9675135,"Diseases of DNA repair",1,13,8.859810536359299E-4,0.4517157454885806,0.5227527106656185,1,25,0.0019287147045209073,9606,Homo sapiens,"NEIL3","","R-HSA-9629245" R-HSA-5654700,"FRS-mediated FGFR2 signaling",2,34,0.002317181217201663,0.46588267022189656,0.5227527106656185,9,9,6.943372936275266E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654615;R-HSA-5654608;R-HSA-5654607;R-HSA-5654399;R-HSA-8941618;R-HSA-5654605;R-HSA-5654397;R-HSA-5654618;R-HSA-5654603" R-HSA-193368,"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol",4,76,0.005179581544333129,0.46618818405912044,0.5227527106656185,2,39,0.003008794939052615,9606,Homo sapiens,"AKR1C1;AKR1C3;AKR1C2","","R-HSA-192160;R-HSA-192036" R-HSA-190377,"FGFR2b ligand binding and activation",1,14,9.541334423771553E-4,0.47649635503999566,0.5227527106656185,3,3,2.3144576454250888E-4,9606,Homo sapiens,"FGF7","","R-HSA-5656070;R-HSA-190260;R-HSA-190408" R-HSA-5638303,"Inhibition of Signaling by Overexpressed EGFR",1,14,9.541334423771553E-4,0.47649635503999566,0.5227527106656185,1,2,1.5429717636167257E-4,9606,Homo sapiens,"BTC","","R-HSA-1225978" R-HSA-5658623,"FGFRL1 modulation of FGFR1 signaling",1,14,9.541334423771553E-4,0.47649635503999566,0.5227527106656185,1,2,1.5429717636167257E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654511" R-HSA-5638302,"Signaling by Overexpressed Wild-Type EGFR in Cancer",1,14,9.541334423771553E-4,0.47649635503999566,0.5227527106656185,1,2,1.5429717636167257E-4,9606,Homo sapiens,"BTC","","R-HSA-1225978" R-HSA-5357786,"TNFR1-induced proapoptotic signaling",1,14,9.541334423771553E-4,0.47649635503999566,0.5227527106656185,1,3,2.3144576454250888E-4,9606,Homo sapiens,"TNFAIP3","","R-HSA-140978" R-HSA-75205,"Dissolution of Fibrin Clot",1,14,9.541334423771553E-4,0.47649635503999566,0.5227527106656185,3,19,0.0014658231754358896,9606,Homo sapiens,"SERPINE1","","R-HSA-158800;R-HSA-158795;R-HSA-159005" R-HSA-9031628,"NGF-stimulated transcription",3,56,0.0038165337695086213,0.4787383438868211,0.5227527106656185,3,36,0.0027773491745101066,9606,Homo sapiens,"FOSL1;F3","","R-HSA-9621042;R-HSA-9031624;R-HSA-9621035" R-HSA-1592389,"Activation of Matrix Metalloproteinases",2,35,0.002385333605942888,0.48086183310494224,0.5227527106656185,9,27,0.00208301188088258,9606,Homo sapiens,"MMP1","","R-HSA-1604712;R-HSA-1592297;R-HSA-1602473;R-HSA-1592362;R-HSA-1604763;R-HSA-1592316;R-HSA-1604690;R-HSA-1592436;R-HSA-1604359" R-HSA-450282,"MAPK targets/ Nuclear events mediated by MAP kinases",2,35,0.002385333605942888,0.48086183310494224,0.5227527106656185,1,16,0.0012343774108933806,9606,Homo sapiens,"DUSP4;POC1A","","R-HSA-203797" R-HSA-9013508,"NOTCH3 Intracellular Domain Regulates Transcription",2,36,0.0024534859946841138,0.49557960066398377,0.5227527106656185,2,22,0.0016972689399783983,9606,Homo sapiens,"DLGAP5","","R-HSA-9018538;R-HSA-9018542" R-HSA-76005,"Response to elevated platelet cytosolic Ca2+",7,144,0.009813943978736455,0.498050605425698,0.5227527106656185,3,14,0.001080080234531708,9606,Homo sapiens,"CLEC3B;TG;SERPINE1;SERPING1;EMILIN2;RAB27B;SEPP1","","R-HSA-481010;R-HSA-481009;R-HSA-481007" R-HSA-1250342,"PI3K events in ERBB4 signaling",1,15,0.0010222858311183807,0.50015854122601,0.5227527106656185,2,2,1.5429717636167257E-4,9606,Homo sapiens,"BTC","","R-HSA-1250370;R-HSA-1250353" R-HSA-190373,"FGFR1c ligand binding and activation",1,15,0.0010222858311183807,0.50015854122601,0.5227527106656185,2,3,2.3144576454250888E-4,9606,Homo sapiens,"FGF5","","R-HSA-190256;R-HSA-190429" R-HSA-1839122,"Signaling by activated point mutants of FGFR1",1,15,0.0010222858311183807,0.50015854122601,0.5227527106656185,2,4,3.0859435272334514E-4,9606,Homo sapiens,"FGF5","","R-HSA-2023455;R-HSA-2023451" R-HSA-5693548,"Sensing of DNA Double Strand Breaks",1,15,0.0010222858311183807,0.50015854122601,0.5227527106656185,2,9,6.943372936275266E-4,9606,Homo sapiens,"KPNA2","","R-HSA-5684006;R-HSA-5684008" R-HSA-9612973,"Autophagy",8,166,0.011313296531043413,0.5007199159473665,0.5227527106656185,9,108,0.00833204752353032,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;RRAGD;TUBB4B","","R-HSA-9646679;R-HSA-9646390;R-HSA-5672017;R-HSA-5672817;R-HSA-5675790;R-HSA-5672010;R-HSA-9646383;R-HSA-5673768;R-HSA-9646685" R-HSA-2162123,"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)",3,58,0.003952838546991072,0.501801220585416,0.5227527106656185,5,32,0.002468754821786761,9606,Homo sapiens,"AKR1C1;TBXAS1;AKR1C3;PTGES","","R-HSA-76500;R-HSA-2161660;R-HSA-2161549;R-HSA-2161613;R-HSA-2161614" R-HSA-140875,"Common Pathway of Fibrin Clot Formation",2,37,0.002521638383425339,0.510029011677128,0.5227527106656185,5,29,0.0022373090572442526,9606,Homo sapiens,"THBD;TG","","R-HSA-140851;R-HSA-141040;R-HSA-141046;R-HSA-140599;R-HSA-140847" R-HSA-5358351,"Signaling by Hedgehog",8,168,0.011449601308525863,0.5141027522751608,0.5227527106656185,24,82,0.006326184230828576,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;GLI1;TUBB4B","","R-HSA-5610741;R-HSA-5635861;R-HSA-5635860;R-HSA-5610742;R-HSA-5610737;R-HSA-5635859;R-HSA-5635868;R-HSA-5635864;R-HSA-5635845;R-HSA-5617412;R-HSA-5610758;R-HSA-5635846;R-HSA-5635841;R-HSA-5617408;R-HSA-5610723;R-HSA-5635843;R-HSA-5635842;R-HSA-5635853;R-HSA-5610733;R-HSA-5610767;R-HSA-5610766;R-HSA-5610760;R-HSA-5635848;R-HSA-5635850" R-HSA-179812,"GRB2 events in EGFR signaling",1,16,0.001090438219859606,0.5227527106656185,0.5227527106656185,2,3,2.3144576454250888E-4,9606,Homo sapiens,"BTC","","R-HSA-177938;R-HSA-177943" R-HSA-4641265,"Repression of WNT target genes",1,16,0.001090438219859606,0.5227527106656185,0.5227527106656185,4,7,5.40040117265854E-4,9606,Homo sapiens,"TCF7","","R-HSA-8944349;R-HSA-8944352;R-HSA-4641231;R-HSA-5229348" R-HSA-351200,"Interconversion of polyamines",1,16,0.001090438219859606,0.5227527106656185,0.5227527106656185,2,7,5.40040117265854E-4,9606,Homo sapiens,"GBP2","","R-HSA-351207;R-HSA-351208" R-HSA-5661231,"Metallothioneins bind metals",1,16,0.001090438219859606,0.5227527106656185,0.5227527106656185,3,27,0.00208301188088258,9606,Homo sapiens,"MT2A","","R-HSA-5662598;R-HSA-5662608;R-HSA-5662986" R-HSA-381426,"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)",6,127,0.008655353370135623,0.5335651425217538,0.5335651425217538,4,14,0.001080080234531708,9606,Homo sapiens,"IGFBP5;MMP1;FAM20A;SCG2;LTBP1","","R-HSA-381537;R-HSA-8952289;R-HSA-381545;R-HSA-381435" R-HSA-109606,"Intrinsic Pathway for Apoptosis",3,61,0.004157295713214748,0.5353836414790148,0.5353836414790148,10,62,0.00478321246721185,9606,Homo sapiens,"BCL2L11;E2F1;BMF","","R-HSA-508163;R-HSA-508162;R-HSA-139908;R-HSA-139909;R-HSA-140217;R-HSA-139918;R-HSA-139919;R-HSA-4331327;R-HSA-4331324;R-HSA-140221" R-HSA-5083635,"Defective B3GALTL causes Peters-plus syndrome (PpS)",2,39,0.00265794316090779,0.5381006250552892,0.5381006250552892,1,1,7.714858818083629E-5,9606,Homo sapiens,"ADAMTS4;ADAMTS3","","R-HSA-6785565" R-HSA-5357905,"Regulation of TNFR1 signaling",2,39,0.00265794316090779,0.5381006250552892,0.5381006250552892,4,14,0.001080080234531708,9606,Homo sapiens,"TNFAIP3;BIRC3","","R-HSA-5693108;R-HSA-5357845;R-HSA-5693055;R-HSA-5357928" R-HSA-5365859,"RA biosynthesis pathway",2,39,0.00265794316090779,0.5381006250552892,0.5381006250552892,2,11,8.486344699891992E-4,9606,Homo sapiens,"AKR1C1;RDH10;AKR1C3","","R-HSA-5615668;R-HSA-5362518" R-HSA-9020591,"Interleukin-12 signaling",4,84,0.0057248006542629315,0.5435346142192506,0.5435346142192506,2,56,0.004320320938126832,9606,Homo sapiens,"SOD2;LMNB1","","R-HSA-8950681;R-HSA-9617941" R-HSA-190375,"FGFR2c ligand binding and activation",1,17,0.0011585906086008315,0.5443270013928303,0.5443270013928303,2,2,1.5429717636167257E-4,9606,Homo sapiens,"FGF5","","R-HSA-190258;R-HSA-190413" R-HSA-1839130,"Signaling by activated point mutants of FGFR3",1,17,0.0011585906086008315,0.5443270013928303,0.5443270013928303,2,6,4.6289152908501776E-4,9606,Homo sapiens,"FGF5","","R-HSA-2012074;R-HSA-2012073" R-HSA-6788467,"IL-6-type cytokine receptor ligand interactions",1,17,0.0011585906086008315,0.5443270013928303,0.5443270013928303,2,14,0.001080080234531708,9606,Homo sapiens,"IL11","","R-HSA-449829;R-HSA-449976" R-HSA-6811555,"PI5P Regulates TP53 Acetylation",1,17,0.0011585906086008315,0.5443270013928303,0.5443270013928303,1,8,6.171887054466903E-4,9606,Homo sapiens,"MAP2K6","","R-HSA-8877691" R-HSA-166166,"MyD88-independent TLR4 cascade ",5,107,0.007292305595311115,0.5502717846210321,0.5502717846210321,25,60,0.004628915290850177,9606,Homo sapiens,"DUSP4;POC1A;CD14;BIRC3;MAP2K6","","R-HSA-2569057;R-HSA-2562541;R-HSA-937029;R-HSA-168915;R-HSA-5362500;R-HSA-203797;R-HSA-936985;R-HSA-450333;R-HSA-2201338;R-HSA-168921;R-HSA-166175;R-HSA-936941;R-HSA-2562564;R-HSA-166245;R-HSA-5362486;R-HSA-450346;R-HSA-450358;R-HSA-936952;R-HSA-2559568;R-HSA-2213017;R-HSA-936951;R-HSA-166271;R-HSA-937075;R-HSA-936947;R-HSA-450296" R-HSA-937061,"TRIF(TICAM1)-mediated TLR4 signaling ",5,107,0.007292305595311115,0.5502717846210321,0.5502717846210321,23,58,0.004474618114488505,9606,Homo sapiens,"DUSP4;POC1A;CD14;BIRC3;MAP2K6","","R-HSA-936941;R-HSA-2562564;R-HSA-2569057;R-HSA-166245;R-HSA-5362486;R-HSA-2562541;R-HSA-937029;R-HSA-450346;R-HSA-450358;R-HSA-168915;R-HSA-5362500;R-HSA-203797;R-HSA-936952;R-HSA-936985;R-HSA-2213017;R-HSA-936951;R-HSA-450333;R-HSA-2201338;R-HSA-168921;R-HSA-166271;R-HSA-937075;R-HSA-936947;R-HSA-450296" R-HSA-390471,"Association of TriC/CCT with target proteins during biosynthesis",2,40,0.002726095549649015,0.5517143459462412,0.5517143459462412,1,2,1.5429717636167257E-4,9606,Homo sapiens,"CCNE2;WRAP53","","R-HSA-390470" R-HSA-170834,"Signaling by TGF-beta Receptor Complex",4,85,0.0057929530430041575,0.5527992253846835,0.5527992253846835,4,82,0.006326184230828576,9606,Homo sapiens,"RBL1;SERPINE1;SCG2","","R-HSA-2186643;R-HSA-1484099;R-HSA-2127257;R-HSA-2106586" R-HSA-193648,"NRAGE signals death through JNK",3,63,0.004293600490697199,0.5570436450849565,0.5570436450849565,2,7,5.40040117265854E-4,9606,Homo sapiens,"BCL2L11;ARHGEF3;ECT2","","R-HSA-205075;R-HSA-205039" R-HSA-9012852,"Signaling by NOTCH3",3,63,0.004293600490697199,0.5570436450849565,0.5570436450849565,3,37,0.0028544977626909426,9606,Homo sapiens,"TACC3;DLGAP5","","R-HSA-9018538;R-HSA-9017855;R-HSA-9018542" R-HSA-5654227,"Phospholipase C-mediated cascade; FGFR3",1,18,0.0012267429973420569,0.5649273848116175,0.5649273848116175,3,3,2.3144576454250888E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654148;R-HSA-5654224;R-HSA-5654222" R-HSA-8847993,"ERBB2 Activates PTK6 Signaling",1,18,0.0012267429973420569,0.5649273848116175,0.5649273848116175,2,2,1.5429717636167257E-4,9606,Homo sapiens,"BTC","","R-HSA-8848005;R-HSA-8847995" R-HSA-5602498,"MyD88 deficiency (TLR2/4)",1,18,0.0012267429973420569,0.5649273848116175,0.5649273848116175,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CD14","","R-HSA-5602383;R-HSA-5602606" R-HSA-964739,"N-glycan trimming and elongation in the cis-Golgi",1,18,0.0012267429973420569,0.5649273848116175,0.5649273848116175,3,5,3.8574294090418145E-4,9606,Homo sapiens,"MAN1C1","","R-HSA-964830;R-HSA-964825;R-HSA-964737" R-HSA-190372,"FGFR3c ligand binding and activation",1,18,0.0012267429973420569,0.5649273848116175,0.5649273848116175,2,4,3.0859435272334514E-4,9606,Homo sapiens,"FGF5","","R-HSA-190388;R-HSA-190261" R-HSA-2160916,"Hyaluronan uptake and degradation",1,18,0.0012267429973420569,0.5649273848116175,0.5649273848116175,3,10,7.714858818083629E-4,9606,Homo sapiens,"HMMR","","R-HSA-2160915;R-HSA-2160884;R-HSA-2160892" R-HSA-975163,"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation",1,18,0.0012267429973420569,0.5649273848116175,0.5649273848116175,1,5,3.8574294090418145E-4,9606,Homo sapiens,"CD14","","R-HSA-450358" R-HSA-5173214,"O-glycosylation of TSR domain-containing proteins",2,41,0.0027942479383902406,0.5650425838534692,0.5650425838534692,2,2,1.5429717636167257E-4,9606,Homo sapiens,"ADAMTS4;ADAMTS3","","R-HSA-5173005;R-HSA-5173192" R-HSA-5654727,"Negative regulation of FGFR2 signaling",2,41,0.0027942479383902406,0.5650425838534692,0.5650425838534692,3,14,0.001080080234531708,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654677;R-HSA-5654562;R-HSA-5654729" R-HSA-8957275,"Post-translational protein phosphorylation",5,109,0.007428610372793566,0.5665781254779632,0.5665781254779632,1,1,7.714858818083629E-5,9606,Homo sapiens,"IGFBP5;FAM20A;SCG2;LTBP1","","R-HSA-8952289" R-HSA-5173105,"O-linked glycosylation",6,132,0.00899611531384175,0.5709305355203866,0.5709305355203866,5,28,0.002160160469063416,9606,Homo sapiens,"ADAMTS4;ADAMTS3;GALNT15;GALNT18;GCNT3","","R-HSA-914012;R-HSA-5173005;R-HSA-913675;R-HSA-5173192;R-HSA-914018" R-HSA-5654696,"Downstream signaling of activated FGFR2",2,42,0.0028624003271314658,0.5780833274049949,0.5780833274049949,22,23,0.0017744175281592346,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654614;R-HSA-5654615;R-HSA-5654612;R-HSA-5654608;R-HSA-5654622;R-HSA-5654399;R-HSA-5654620;R-HSA-5654397;R-HSA-5654618;R-HSA-5654406;R-HSA-5654407;R-HSA-5654404;R-HSA-5654402;R-HSA-5654147;R-HSA-5654607;R-HSA-5654159;R-HSA-8941618;R-HSA-5654701;R-HSA-5654605;R-HSA-5654157;R-HSA-5654603;R-HSA-5654697" R-HSA-1483166,"Synthesis of PA",3,65,0.00442990526817965,0.5780867418315287,0.5780867418315287,2,17,0.001311525999074217,9606,Homo sapiens,"CFI;PLD1","","R-HSA-1602446;R-HSA-1483182" R-HSA-937072,"TRAF6-mediated induction of TAK1 complex within TLR4 complex",1,19,0.0012948953860832822,0.584597763074949,0.584597763074949,6,6,4.6289152908501776E-4,9606,Homo sapiens,"CD14","","R-HSA-450358;R-HSA-936952;R-HSA-936985;R-HSA-936951;R-HSA-937075;R-HSA-936947" R-HSA-180336,"SHC1 events in EGFR signaling",1,19,0.0012948953860832822,0.584597763074949,0.584597763074949,4,4,3.0859435272334514E-4,9606,Homo sapiens,"BTC","","R-HSA-177936;R-HSA-177925;R-HSA-177945;R-HSA-177933" R-HSA-6785631,"ERBB2 Regulates Cell Motility",1,19,0.0012948953860832822,0.584597763074949,0.584597763074949,2,2,1.5429717636167257E-4,9606,Homo sapiens,"BTC","","R-HSA-6785636;R-HSA-6785648" R-HSA-5603041,"IRAK4 deficiency (TLR2/4)",1,19,0.0012948953860832822,0.584597763074949,0.584597763074949,2,2,1.5429717636167257E-4,9606,Homo sapiens,"CD14","","R-HSA-5602353;R-HSA-5602672" R-HSA-190239,"FGFR3 ligand binding and activation",1,19,0.0012948953860832822,0.584597763074949,0.584597763074949,2,6,4.6289152908501776E-4,9606,Homo sapiens,"FGF5","","R-HSA-190388;R-HSA-190261" R-HSA-168927,"TICAM1, RIP1-mediated IKK complex recruitment",1,19,0.0012948953860832822,0.584597763074949,0.584597763074949,1,3,2.3144576454250888E-4,9606,Homo sapiens,"BIRC3","","R-HSA-9014342" R-HSA-419408,"Lysosphingolipid and LPA receptors",1,19,0.0012948953860832822,0.584597763074949,0.584597763074949,1,3,2.3144576454250888E-4,9606,Homo sapiens,"S1PR3","","R-HSA-419428" R-HSA-5689896,"Ovarian tumor domain proteases",2,43,0.0029305527158726913,0.5908353277149678,0.5908353277149678,7,14,0.001080080234531708,9606,Homo sapiens,"CDK1;TNFAIP3","","R-HSA-5690870;R-HSA-688136;R-HSA-8869506;R-HSA-5690845;R-HSA-8940100;R-HSA-5690827;R-HSA-5690856" R-HSA-156590,"Glutathione conjugation",3,67,0.0045662100456621,0.5984903248590421,0.5984903248590421,2,14,0.001080080234531708,9606,Homo sapiens,"GSTM3;CHAC2","","R-HSA-176054;R-HSA-6785928" R-HSA-3769402,"Deactivation of the beta-catenin transactivating complex",2,44,0.002998705104613917,0.6032980338084896,0.6032980338084896,3,14,0.001080080234531708,9606,Homo sapiens,"TCF7;SCG2","","R-HSA-3361751;R-HSA-3364042;R-HSA-5665608" R-HSA-936964,"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon",1,20,0.0013630477748245075,0.6033800620936671,0.6033800620936671,7,9,6.943372936275266E-4,9606,Homo sapiens,"CD14","","R-HSA-936941;R-HSA-5362500;R-HSA-166245;R-HSA-5362486;R-HSA-2213017;R-HSA-2201338;R-HSA-166271" R-HSA-388844,"Receptor-type tyrosine-protein phosphatases",1,20,0.0013630477748245075,0.6033800620936671,0.6033800620936671,2,6,4.6289152908501776E-4,9606,Homo sapiens,"PTPRF","","R-HSA-6798258;R-HSA-388824" R-HSA-140534,"Caspase activation via Death Receptors in the presence of ligand",1,20,0.0013630477748245075,0.6033800620936671,0.6033800620936671,1,9,6.943372936275266E-4,9606,Homo sapiens,"CD14","","R-HSA-2562564" R-HSA-3232118,"SUMOylation of transcription factors",1,20,0.0013630477748245075,0.6033800620936671,0.6033800620936671,1,11,8.486344699891992E-4,9606,Homo sapiens,"MITF","","R-HSA-3232162" R-HSA-9006936,"Signaling by TGFB family members",5,114,0.007769372316499694,0.6059673397682981,0.6059673397682981,12,107,0.008254898935349484,9606,Homo sapiens,"BMP2;RBL1;SERPINE1;SCG2","","R-HSA-201475;R-HSA-201443;R-HSA-201810;R-HSA-2186643;R-HSA-201457;R-HSA-201648;R-HSA-1484099;R-HSA-201476;R-HSA-2127257;R-HSA-2106586;R-HSA-201821;R-HSA-201453" R-HSA-450294,"MAP kinase activation",3,69,0.004702514823144551,0.618237254340507,0.618237254340507,4,32,0.002468754821786761,9606,Homo sapiens,"DUSP4;POC1A;MAP2K6","","R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-1250347,"SHC1 events in ERBB4 signaling",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,4,4,3.0859435272334514E-4,9606,Homo sapiens,"BTC","","R-HSA-1250357;R-HSA-1250383;R-HSA-1250380;R-HSA-1250348" R-HSA-1963640,"GRB2 events in ERBB2 signaling",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,2,4,3.0859435272334514E-4,9606,Homo sapiens,"BTC","","R-HSA-1306969;R-HSA-1306972" R-HSA-190242,"FGFR1 ligand binding and activation",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,2,7,5.40040117265854E-4,9606,Homo sapiens,"FGF5","","R-HSA-190256;R-HSA-190429" R-HSA-5675482,"Regulation of necroptotic cell death",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,1,5,3.8574294090418145E-4,9606,Homo sapiens,"BIRC3","","R-HSA-5675470" R-HSA-9671793,"Diseases of hemostasis",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,3,18,0.0013886745872550533,9606,Homo sapiens,"SERPING1","","R-HSA-9651456;R-HSA-9651467;R-HSA-9650447" R-HSA-9651496,"Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,3,18,0.0013886745872550533,9606,Homo sapiens,"SERPING1","","R-HSA-9651456;R-HSA-9651467;R-HSA-9650447" R-HSA-5660526,"Response to metal ions",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,3,31,0.002391606233605925,9606,Homo sapiens,"MT2A","","R-HSA-5662598;R-HSA-5662608;R-HSA-5662986" R-HSA-8866910,"TFAP2 (AP-2) family regulates transcription of growth factors and their receptors",1,21,0.0014312001635657329,0.6213143203705209,0.6213143203705209,1,18,0.0013886745872550533,9606,Homo sapiens,"ATAD2","","R-HSA-8937369" R-HSA-909733,"Interferon alpha/beta signaling",8,186,0.01267634430586792,0.627832944502813,0.627832944502813,2,20,0.0015429717636167258,9606,Homo sapiens,"ISG20;GBP2;IFIT1;IFIT2","","R-HSA-1015702;R-HSA-1015699" R-HSA-69563,"p53-Dependent G1 DNA Damage Response",3,70,0.004770667211885776,0.6278604908524331,0.6278604908524331,2,22,0.0016972689399783983,9606,Homo sapiens,"CCNA2;CCNE2;CDK2","","R-HSA-69562;R-HSA-187934" R-HSA-69580,"p53-Dependent G1/S DNA damage checkpoint",3,70,0.004770667211885776,0.6278604908524331,0.6278604908524331,2,22,0.0016972689399783983,9606,Homo sapiens,"CCNA2;CCNE2;CDK2","","R-HSA-69562;R-HSA-187934" R-HSA-168643,"Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways",3,70,0.004770667211885776,0.6278604908524331,0.6278604908524331,4,46,0.003548835056318469,9606,Homo sapiens,"TNFAIP3;BIRC3;MAP2K6","","R-HSA-727819;R-HSA-688136;R-HSA-688137;R-HSA-1247960" R-HSA-199977,"ER to Golgi Anterograde Transport",7,164,0.011176991753560963,0.6336197050685832,0.6336197050685832,2,39,0.003008794939052615,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B","","R-HSA-6809006;R-HSA-6809003" R-HSA-5654219,"Phospholipase C-mediated cascade: FGFR1",1,22,0.0014993525523069584,0.6384387738468544,0.6384387738468544,3,3,2.3144576454250888E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654167;R-HSA-5654165;R-HSA-5654149" R-HSA-4641263,"Regulation of FZD by ubiquitination",1,22,0.0014993525523069584,0.6384387738468544,0.6384387738468544,3,6,4.6289152908501776E-4,9606,Homo sapiens,"RSPO2","","R-HSA-4641206;R-HSA-4641205;R-HSA-4641246" R-HSA-1963642,"PI3K events in ERBB2 signaling",1,22,0.0014993525523069584,0.6384387738468544,0.6384387738468544,2,7,5.40040117265854E-4,9606,Homo sapiens,"BTC","","R-HSA-1306979;R-HSA-1250346" R-HSA-400511,"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)",1,22,0.0014993525523069584,0.6384387738468544,0.6384387738468544,1,7,5.40040117265854E-4,9606,Homo sapiens,"SPC25","","R-HSA-400496" R-HSA-5210891,"Uptake and function of anthrax toxins",1,22,0.0014993525523069584,0.6384387738468544,0.6384387738468544,1,19,0.0014658231754358896,9606,Homo sapiens,"MAP2K6","","R-HSA-5211405" R-HSA-5362517,"Signaling by Retinoic Acid",3,72,0.0049069719893682275,0.646601051703922,0.646601051703922,6,21,0.001620120351797562,9606,Homo sapiens,"FABP5;AKR1C1;RDH10;AKR1C3","","R-HSA-5615668;R-HSA-5634100;R-HSA-5622129;R-HSA-5362518;R-HSA-5422942;R-HSA-5633256" R-HSA-447115,"Interleukin-12 family signaling",4,96,0.006542629319157636,0.6475866395634667,0.6475866395634667,2,114,0.008794939052615337,9606,Homo sapiens,"SOD2;LMNB1","","R-HSA-8950681;R-HSA-9617941" R-HSA-71240,"Tryptophan catabolism",2,48,0.003271314659578818,0.6502660564261958,0.6502660564261958,2,16,0.0012343774108933806,9606,Homo sapiens,"SLC7A5;KYNU","","R-HSA-71217;R-HSA-352232" R-HSA-8853884,"Transcriptional Regulation by VENTX",2,48,0.003271314659578818,0.6502660564261958,0.6502660564261958,1,13,0.0010029316463508718,9606,Homo sapiens,"UBE2S;UBE2C","","R-HSA-3790130" R-HSA-180292,"GAB1 signalosome",1,23,0.0015675049410481838,0.6547899369402148,0.6547899369402148,9,11,8.486344699891992E-4,9606,Homo sapiens,"BTC","","R-HSA-177923;R-HSA-177939;R-HSA-177926;R-HSA-177927;R-HSA-177924;R-HSA-177941;R-HSA-177930;R-HSA-177944;R-HSA-177935" R-HSA-2142670,"Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)",1,23,0.0015675049410481838,0.6547899369402148,0.6547899369402148,1,3,2.3144576454250888E-4,9606,Homo sapiens,"EPHX2","","R-HSA-2161961" R-HSA-2142845,"Hyaluronan metabolism",1,23,0.0015675049410481838,0.6547899369402148,0.6547899369402148,3,13,0.0010029316463508718,9606,Homo sapiens,"HMMR","","R-HSA-2160915;R-HSA-2160884;R-HSA-2160892" R-HSA-8849932,"Synaptic adhesion-like molecules",1,23,0.0015675049410481838,0.6547899369402148,0.6547899369402148,1,8,6.171887054466903E-4,9606,Homo sapiens,"PTPRF","","R-HSA-8855648" R-HSA-109582,"Hemostasis",36,824,0.05615756832276971,0.6587719916348863,0.6587719916348863,40,332,0.025613331276037647,9606,Homo sapiens,"HIST1H3J;SERPINE1;KIF11;KIF15;THBD;TUBA1C;CLEC3B;TUBB6;TUBA1B;RACGAP1;TUBB3;EMILIN2;HIST1H3B;GUCY1A2;MMP1;PSG1;KIF23;RAB27B;KIF22;TUBB4B;F3;SEPP1;CENPE;SLC7A5;KIF18A;KIF18B;TG;KIFC1;KIF4A;CDK2;SERPING1;KIF2C;DOCK2;KIF20B","","R-HSA-997263;R-HSA-990478;R-HSA-1011598;R-HSA-140736;R-HSA-984648;R-HSA-158795;R-HSA-392143;R-HSA-8870732;R-HSA-140748;R-HSA-984671;R-HSA-984606;R-HSA-158800;R-HSA-983259;R-HSA-140823;R-HSA-990489;R-HSA-158357;R-HSA-375135;R-HSA-140825;R-HSA-140761;R-HSA-392152;R-HSA-375131;R-HSA-159005;R-HSA-481007;R-HSA-140777;R-HSA-140847;R-HSA-983266;R-HSA-140783;R-HSA-984609;R-HSA-140851;R-HSA-141040;R-HSA-141046;R-HSA-481010;R-HSA-140599;R-HSA-994106;R-HSA-481009;R-HSA-1013881;R-HSA-9650473;R-HSA-984821;R-HSA-158399;R-HSA-984689" R-HSA-1839126,"FGFR2 mutant receptor activation",2,49,0.0033394670483200438,0.6612944499798237,0.6612944499798237,6,18,0.0013886745872550533,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-2033486;R-HSA-2077421;R-HSA-2033474;R-HSA-2077424;R-HSA-2033472;R-HSA-2033488" R-HSA-5675221,"Negative regulation of MAPK pathway",2,49,0.0033394670483200438,0.6612944499798237,0.6612944499798237,2,17,0.001311525999074217,9606,Homo sapiens,"DUSP4;POC1A","","R-HSA-5675376;R-HSA-5675373" R-HSA-5689603,"UCH proteinases",4,98,0.0066789340966400875,0.6633150465183486,0.6633150465183486,1,11,8.486344699891992E-4,9606,Homo sapiens,"HIST1H2AH;HIST1H2AK;HIST1H2AE;HIST1H2AD","","R-HSA-5690790" R-HSA-5654710,"PI-3K cascade:FGFR3",1,24,0.001635657329789409,0.6704026799441973,0.6704026799441973,6,7,5.40040117265854E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654709;R-HSA-5654643;R-HSA-5654640;R-HSA-5654641;R-HSA-5654705;R-HSA-5654637" R-HSA-2243919,"Crosslinking of collagen fibrils",1,24,0.001635657329789409,0.6704026799441973,0.6704026799441973,3,13,0.0010029316463508718,9606,Homo sapiens,"LOXL3","","R-HSA-2022141;R-HSA-2395340;R-HSA-2002466" R-HSA-75893,"TNF signaling",2,50,0.003407619437061269,0.6720417899504685,0.6720417899504685,10,29,0.0022373090572442526,9606,Homo sapiens,"TNFAIP3;BIRC3","","R-HSA-140978;R-HSA-5357776;R-HSA-5357904;R-HSA-5693108;R-HSA-5357845;R-HSA-5357860;R-HSA-5357780;R-HSA-5693055;R-HSA-5357928;R-HSA-5357757" R-HSA-75876,"Synthesis of very long-chain fatty acyl-CoAs",2,51,0.0034757718258024944,0.6825109306620725,0.6825109306620725,3,12,9.257830581700355E-4,9606,Homo sapiens,"DEPDC1B;ELOVL3","","R-HSA-548814;R-HSA-548815;R-HSA-548800" R-HSA-6807004,"Negative regulation of MET activity",1,25,0.0017038097185306344,0.6853103029531813,0.6853103029531813,4,10,7.714858818083629E-4,9606,Homo sapiens,"LIG1","","R-HSA-8875431;R-HSA-8875443;R-HSA-8875490;R-HSA-8875374" R-HSA-211979,"Eicosanoids",1,25,0.0017038097185306344,0.6853103029531813,0.6853103029531813,1,6,4.6289152908501776E-4,9606,Homo sapiens,"TBXAS1","","R-HSA-76500" R-HSA-1482922,"Acyl chain remodelling of PI",1,25,0.0017038097185306344,0.6853103029531813,0.6853103029531813,1,6,4.6289152908501776E-4,9606,Homo sapiens,"CFI","","R-HSA-1602377" R-HSA-977347,"Serine biosynthesis",1,25,0.0017038097185306344,0.6853103029531813,0.6853103029531813,1,7,5.40040117265854E-4,9606,Homo sapiens,"PSPH","","R-HSA-977324" R-HSA-448424,"Interleukin-17 signaling",3,77,0.005247733933074354,0.6904798851695035,0.6904798851695035,4,35,0.00270020058632927,9606,Homo sapiens,"DUSP4;POC1A;MAP2K6","","R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-975138,"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation",4,102,0.006951543651604989,0.6933165112054118,0.6933165112054118,5,48,0.003703132232680142,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-450358;R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-168164,"Toll Like Receptor 3 (TLR3) Cascade",4,102,0.006951543651604989,0.6933165112054118,0.6933165112054118,5,61,0.004706063879031014,9606,Homo sapiens,"DUSP4;POC1A;BIRC3;MAP2K6","","R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296;R-HSA-9014342" R-HSA-5654704,"SHC-mediated cascade:FGFR3",1,26,0.0017719621072718598,0.6995446064679016,0.6995446064679016,4,4,3.0859435272334514E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654646;R-HSA-5654647;R-HSA-5654625;R-HSA-5654634" R-HSA-70221,"Glycogen breakdown (glycogenolysis)",1,26,0.0017719621072718598,0.6995446064679016,0.6995446064679016,2,15,0.0011572288227125443,9606,Homo sapiens,"PHKG1","","R-HSA-71541;R-HSA-453337" R-HSA-422085,"Synthesis, secretion, and deacylation of Ghrelin",1,26,0.0017719621072718598,0.6995446064679016,0.6995446064679016,1,8,6.171887054466903E-4,9606,Homo sapiens,"SPC25","","R-HSA-422051" R-HSA-174403,"Glutathione synthesis and recycling",1,26,0.0017719621072718598,0.6995446064679016,0.6995446064679016,1,9,6.943372936275266E-4,9606,Homo sapiens,"CHAC2","","R-HSA-6785928" R-HSA-975155,"MyD88 dependent cascade initiated on endosome",4,103,0.007019696040346214,0.700511761610902,0.700511761610902,5,63,0.004860361055392687,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-450358;R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-168181,"Toll Like Receptor 7/8 (TLR7/8) Cascade",4,103,0.007019696040346214,0.700511761610902,0.700511761610902,5,64,0.004937509643573522,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-450358;R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-975634,"Retinoid metabolism and transport",3,79,0.005384038710556805,0.7068443544549126,0.7068443544549126,1,28,0.002160160469063416,9606,Homo sapiens,"AKR1C1;AKR1C3","","R-HSA-2855252" R-HSA-5654706,"FRS-mediated FGFR3 signaling",1,27,0.0018401144960130853,0.7131359588307817,0.7131359588307817,9,9,6.943372936275266E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654631;R-HSA-5654628;R-HSA-8941628;R-HSA-5654416;R-HSA-5654623;R-HSA-5654413;R-HSA-5654408;R-HSA-5654633;R-HSA-5654409" R-HSA-450302,"activated TAK1 mediates p38 MAPK activation",1,27,0.0018401144960130853,0.7131359588307817,0.7131359588307817,3,5,3.8574294090418145E-4,9606,Homo sapiens,"MAP2K6","","R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-2033514,"FGFR3 mutant receptor activation",1,27,0.0018401144960130853,0.7131359588307817,0.7131359588307817,3,9,6.943372936275266E-4,9606,Homo sapiens,"FGF5","","R-HSA-2077420;R-HSA-2012074;R-HSA-2012073" R-HSA-166208,"mTORC1-mediated signalling",1,27,0.0018401144960130853,0.7131359588307817,0.7131359588307817,2,7,5.40040117265854E-4,9606,Homo sapiens,"RRAGD","","R-HSA-165718;R-HSA-165692" R-HSA-204998,"Cell death signalling via NRAGE, NRIF and NADE",3,80,0.00545219109929803,0.7147745272328266,0.7147745272328266,2,17,0.001311525999074217,9606,Homo sapiens,"BCL2L11;ARHGEF3;ECT2","","R-HSA-205075;R-HSA-205039" R-HSA-174113,"SCF-beta-TrCP mediated degradation of Emi1",2,55,0.0037483813807673958,0.7216729201056682,0.7216729201056682,3,3,2.3144576454250888E-4,9606,Homo sapiens,"CDC20;FBXO5","","R-HSA-174209;R-HSA-174203;R-HSA-174159" R-HSA-499943,"Interconversion of nucleotide di- and triphosphates",3,81,0.005520343488039256,0.7225379318684961,0.7225379318684961,5,33,0.0025459034099675976,9606,Homo sapiens,"RRM2;TYMS;AK8","","R-HSA-73605;R-HSA-111751;R-HSA-110137;R-HSA-110138;R-HSA-111742" R-HSA-5654689,"PI-3K cascade:FGFR1",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,6,7,5.40040117265854E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654692;R-HSA-5654596;R-HSA-5654594;R-HSA-5654690;R-HSA-5654592;R-HSA-5654591" R-HSA-5213460,"RIPK1-mediated regulated necrosis",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,2,13,0.0010029316463508718,9606,Homo sapiens,"BIRC3","","R-HSA-5675470;R-HSA-5213462" R-HSA-5218859,"Regulated Necrosis",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,2,13,0.0010029316463508718,9606,Homo sapiens,"BIRC3","","R-HSA-5675470;R-HSA-5213462" R-HSA-71384,"Ethanol oxidation",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,1,8,6.171887054466903E-4,9606,Homo sapiens,"ACSS1","","R-HSA-449911" R-HSA-3238698,"WNT ligand biogenesis and trafficking",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,1,12,9.257830581700355E-4,9606,Homo sapiens,"PORCN","","R-HSA-3238694" R-HSA-9013507,"NOTCH3 Activation and Transmission of Signal to the Nucleus",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,1,15,0.0011572288227125443,9606,Homo sapiens,"TACC3","","R-HSA-9017855" R-HSA-189200,"Cellular hexose transport",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,1,17,0.001311525999074217,9606,Homo sapiens,"SLC2A12","","R-HSA-429094" R-HSA-8964038,"LDL clearance",1,28,0.0019082668847543107,0.7261133606328354,0.7261133606328354,1,19,0.0014658231754358896,9606,Homo sapiens,"LSR","","R-HSA-8933258" R-HSA-168138,"Toll Like Receptor 9 (TLR9) Cascade",4,107,0.007292305595311115,0.7280721275596455,0.7280721275596455,5,67,0.005168955408116032,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-450358;R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-597592,"Post-translational protein modification",69,1594,0.10863490765351326,0.7345017200218678,0.7345017200218678,72,526,0.04058015738311989,9606,Homo sapiens,"TOP2A;GALNT15;GALNT18;LRR1;CCNF;TNFAIP3;BRCA1;GMPPB;CDC20;ADAMTS4;TUBA1C;TUBB6;TUBA1B;ADAMTS3;TUBB3;HIST1H2AE;HIST1H2AD;IGFBP5;HIST1H2AH;HIST1H2AK;HIST2H2BB;MITF;RENBP;HIST2H2BF;RAB33A;CDC25A;CCNA2;RTN4RL1;INCENP;HIST1H2BF;BIRC5;HIST1H2BE;FAM20A;HIST1H2BG;HIST1H2BB;SCG2;DTL;HIST1H2BD;HIST1H2BC;BIRC3;HIST1H2BN;HIST1H2BM;BLM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;CDCA8;LTBP1;AURKB;AURKA;HIST2H4A;RAB20;MAN1C1;GCNT3;CLSPN;UBE2C;HIST1H4L;RAB27B;TUBB4B;HIST1H4B;RAET1G;UBE2S;UBE2T;CDK2;CDK1;HIST1H4H;HIST1H4C;KBTBD8;HIST1H4D;HIST1H4E","","R-HSA-8956040;R-HSA-4641350;R-HSA-688136;R-HSA-6781797;R-HSA-8956045;R-HSA-8869506;R-HSA-913675;R-HSA-5173192;R-HSA-5690845;R-HSA-446221;R-HSA-5696600;R-HSA-964737;R-HSA-8955289;R-HSA-3232162;R-HSA-8943003;R-HSA-5696960;R-HSA-4568914;R-HSA-8943007;R-HSA-8852127;R-HSA-8942099;R-HSA-8942101;R-HSA-8955285;R-HSA-5690827;R-HSA-8956200;R-HSA-5690870;R-HSA-8952618;R-HSA-5228525;R-HSA-5691381;R-HSA-8952620;R-HSA-8852130;R-HSA-8852129;R-HSA-5697009;R-HSA-8867370;R-HSA-4570485;R-HSA-8955706;R-HSA-5690080;R-HSA-8952638;R-HSA-8952639;R-HSA-4655355;R-HSA-8866105;R-HSA-5690856;R-HSA-8870469;R-HSA-5173005;R-HSA-5696914;R-HSA-8870466;R-HSA-5691411;R-HSA-4570496;R-HSA-8955712;R-HSA-8943040;R-HSA-6809006;R-HSA-8943041;R-HSA-8940100;R-HSA-6809003;R-HSA-964830;R-HSA-914012;R-HSA-8955869;R-HSA-6803761;R-HSA-964825;R-HSA-2997616;R-HSA-2997709;R-HSA-8955241;R-HSA-8955245;R-HSA-5696958;R-HSA-8952289;R-HSA-8865774;R-HSA-4655404;R-HSA-8940388;R-HSA-914018;R-HSA-5690790;R-HSA-8956026;R-HSA-4641342;R-HSA-5690157" R-HSA-446210,"Synthesis of UDP-N-acetyl-glucosamine",1,29,0.001976419273495536,0.7385045062283915,0.7385045062283915,1,7,5.40040117265854E-4,9606,Homo sapiens,"RENBP","","R-HSA-6803761" R-HSA-9634638,"Estrogen-dependent nuclear events downstream of ESR-membrane signaling",1,29,0.001976419273495536,0.7385045062283915,0.7385045062283915,1,12,9.257830581700355E-4,9606,Homo sapiens,"BTC","","R-HSA-9625465" R-HSA-9018682,"Biosynthesis of maresins",1,29,0.001976419273495536,0.7385045062283915,0.7385045062283915,1,13,0.0010029316463508718,9606,Homo sapiens,"EPHX2","","R-HSA-9024993" R-HSA-164952,"The role of Nef in HIV-1 replication and disease pathogenesis",1,29,0.001976419273495536,0.7385045062283915,0.7385045062283915,1,20,0.0015429717636167258,9606,Homo sapiens,"DOCK2","","R-HSA-200952" R-HSA-1483206,"Glycerophospholipid biosynthesis",9,232,0.01581135418796429,0.7442833839315124,0.7442833839315124,20,133,0.010260762228051227,9606,Homo sapiens,"TMEM86A;MCM8;RARRES3;CFI;PLD1;NES;MFSD2A","","R-HSA-1482646;R-HSA-1483063;R-HSA-8865637;R-HSA-8874435;R-HSA-1482546;R-HSA-1482547;R-HSA-1602398;R-HSA-1602417;R-HSA-1483142;R-HSA-1602377;R-HSA-1482533;R-HSA-1482691;R-HSA-1602446;R-HSA-1482689;R-HSA-1483182;R-HSA-1602368;R-HSA-1482636;R-HSA-8858298;R-HSA-1482667;R-HSA-1602374" R-HSA-109704,"PI3K Cascade",2,58,0.003952838546991072,0.7483031790057915,0.7483031790057915,1,6,4.6289152908501776E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-109699" R-HSA-5654688,"SHC-mediated cascade:FGFR1",1,30,0.0020445716622367613,0.7503358424869995,0.7503358424869995,4,4,3.0859435272334514E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654582;R-HSA-5654597;R-HSA-5654573;R-HSA-5654600" R-HSA-201451,"Signaling by BMP",1,30,0.0020445716622367613,0.7503358424869995,0.7503358424869995,8,17,0.001311525999074217,9606,Homo sapiens,"BMP2","","R-HSA-201475;R-HSA-201443;R-HSA-201810;R-HSA-201457;R-HSA-201648;R-HSA-201476;R-HSA-201821;R-HSA-201453" R-HSA-420029,"Tight junction interactions",1,30,0.0020445716622367613,0.7503358424869995,0.7503358424869995,1,3,2.3144576454250888E-4,9606,Homo sapiens,"CLDN23","","R-HSA-420019" R-HSA-168188,"Toll Like Receptor TLR6:TLR2 Cascade",4,111,0.0075649151502760175,0.7536951589989743,0.7536951589989743,22,66,0.005091806819935195,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-166082;R-HSA-2201316;R-HSA-166119;R-HSA-166091;R-HSA-2201322;R-HSA-450346;R-HSA-166286;R-HSA-937059;R-HSA-166284;R-HSA-2559464;R-HSA-937022;R-HSA-2559414;R-HSA-168950;R-HSA-2262775;R-HSA-203797;R-HSA-166362;R-HSA-937079;R-HSA-166363;R-HSA-166072;R-HSA-450333;R-HSA-2262777;R-HSA-450296" R-HSA-166058,"MyD88:MAL(TIRAP) cascade initiated on plasma membrane",4,111,0.0075649151502760175,0.7536951589989743,0.7536951589989743,20,64,0.004937509643573522,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-166082;R-HSA-2201316;R-HSA-166119;R-HSA-166091;R-HSA-2201322;R-HSA-450346;R-HSA-166286;R-HSA-937059;R-HSA-166284;R-HSA-937022;R-HSA-2559414;R-HSA-2262775;R-HSA-203797;R-HSA-166362;R-HSA-937079;R-HSA-166363;R-HSA-166072;R-HSA-450333;R-HSA-2262777;R-HSA-450296" R-HSA-192105,"Synthesis of bile acids and bile salts",4,111,0.0075649151502760175,0.7536951589989743,0.7536951589989743,6,83,0.006403332819009412,9606,Homo sapiens,"AKR1C1;AKR1C3;AKR1C2","","R-HSA-192160;R-HSA-193841;R-HSA-192036;R-HSA-193781;R-HSA-193800;R-HSA-193758" R-HSA-5654693,"FRS-mediated FGFR1 signaling",1,31,0.002112724050977987,0.7616326249065404,0.7616326249065404,9,9,6.943372936275266E-4,9606,Homo sapiens,"FGF5","","R-HSA-5654578;R-HSA-5654575;R-HSA-5654586;R-HSA-5654587;R-HSA-5654571;R-HSA-5654584;R-HSA-5654392;R-HSA-8941623;R-HSA-5654569" R-HSA-1971475,"A tetrasaccharide linker sequence is required for GAG synthesis",1,31,0.002112724050977987,0.7616326249065404,0.7616326249065404,1,5,3.8574294090418145E-4,9606,Homo sapiens,"XYLT1","","R-HSA-1878002" R-HSA-1187000,"Fertilization",1,31,0.002112724050977987,0.7616326249065404,0.7616326249065404,1,9,6.943372936275266E-4,9606,Homo sapiens,"OVGP1","","R-HSA-1297338" R-HSA-5686938,"Regulation of TLR by endogenous ligand",1,31,0.002112724050977987,0.7616326249065404,0.7616326249065404,1,12,9.257830581700355E-4,9606,Homo sapiens,"CD14","","R-HSA-8869694" R-HSA-5601884,"PIWI-interacting RNA (piRNA) biogenesis",1,31,0.002112724050977987,0.7616326249065404,0.7616326249065404,1,15,0.0011572288227125443,9606,Homo sapiens,"MYBL1","","R-HSA-5601926" R-HSA-181438,"Toll Like Receptor 2 (TLR2) Cascade",4,114,0.007769372316499694,0.7716636851803498,0.7716636851803498,24,68,0.005246103996296868,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-166082;R-HSA-2201316;R-HSA-166119;R-HSA-166091;R-HSA-2201322;R-HSA-2559468;R-HSA-450346;R-HSA-166286;R-HSA-937059;R-HSA-166284;R-HSA-2559464;R-HSA-937022;R-HSA-2559414;R-HSA-168950;R-HSA-2262775;R-HSA-168951;R-HSA-203797;R-HSA-166362;R-HSA-937079;R-HSA-166363;R-HSA-166072;R-HSA-450333;R-HSA-2262777;R-HSA-450296" R-HSA-168179,"Toll Like Receptor TLR1:TLR2 Cascade",4,114,0.007769372316499694,0.7716636851803498,0.7716636851803498,22,66,0.005091806819935195,9606,Homo sapiens,"DUSP4;POC1A;CD14;MAP2K6","","R-HSA-166082;R-HSA-2201316;R-HSA-166119;R-HSA-166091;R-HSA-2201322;R-HSA-2559468;R-HSA-450346;R-HSA-166286;R-HSA-937059;R-HSA-166284;R-HSA-937022;R-HSA-2559414;R-HSA-2262775;R-HSA-168951;R-HSA-203797;R-HSA-166362;R-HSA-937079;R-HSA-166363;R-HSA-166072;R-HSA-450333;R-HSA-2262777;R-HSA-450296" R-HSA-2046105,"Linoleic acid (LA) metabolism",1,32,0.002180876439719212,0.7724189712059784,0.7724189712059784,1,10,7.714858818083629E-4,9606,Homo sapiens,"ELOVL3","","R-HSA-2046094" R-HSA-9639288,"Amino acids regulate mTORC1",2,61,0.004157295713214748,0.7727146567591486,0.7727146567591486,12,12,9.257830581700355E-4,9606,Homo sapiens,"RRAGD;KLF15","","R-HSA-9657619;R-HSA-9640195;R-HSA-9639287;R-HSA-9640167;R-HSA-9639286;R-HSA-9646468;R-HSA-9640168;R-HSA-9645608;R-HSA-9640175;R-HSA-9640254;R-HSA-9645598;R-HSA-9640237" R-HSA-177929,"Signaling by EGFR",2,61,0.004157295713214748,0.7727146567591486,0.7727146567591486,40,49,0.003780280820860978,9606,Homo sapiens,"BTC;LIG1","","R-HSA-177922;R-HSA-177923;R-HSA-177926;R-HSA-177927;R-HSA-177924;R-HSA-177925;R-HSA-177930;R-HSA-182986;R-HSA-183051;R-HSA-8951490;R-HSA-177934;R-HSA-182990;R-HSA-177935;R-HSA-183055;R-HSA-177933;R-HSA-177938;R-HSA-183058;R-HSA-182994;R-HSA-177939;R-HSA-177936;R-HSA-177937;R-HSA-182993;R-HSA-177942;R-HSA-177943;R-HSA-177941;R-HSA-183002;R-HSA-183067;R-HSA-177944;R-HSA-177945;R-HSA-8867047;R-HSA-212706;R-HSA-183072;R-HSA-8867044;R-HSA-212710;R-HSA-8867041;R-HSA-212713;R-HSA-183084;R-HSA-183089;R-HSA-182969;R-HSA-183036" R-HSA-199991,"Membrane Trafficking",27,665,0.04532133851291488,0.7793054311161758,0.7793054311161758,37,218,0.01681839222342231,9606,Homo sapiens,"KIF23;RAB27B;STON2;KIF22;KIF11;TUBB4B;RAB33A;KIF15;BTC;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;KIF18B;RACGAP1;KIFC1;TUBB3;KIF4A;CDK2;AGTR1;MAN1C1;KIF2C;KIF20B","","R-HSA-8868230;R-HSA-8849350;R-HSA-6811426;R-HSA-6809006;R-HSA-8868236;R-HSA-6809003;R-HSA-8849353;R-HSA-8854612;R-HSA-8847635;R-HSA-2316347;R-HSA-8866269;R-HSA-8871194;R-HSA-8871193;R-HSA-190877;R-HSA-8868071;R-HSA-8863463;R-HSA-8866279;R-HSA-8863727;R-HSA-8867756;R-HSA-8863723;R-HSA-8868651;R-HSA-8866283;R-HSA-8867754;R-HSA-8863721;R-HSA-8868072;R-HSA-8868648;R-HSA-8868661;R-HSA-8868660;R-HSA-8868659;R-HSA-8868658;R-HSA-6811423;R-HSA-8869438;R-HSA-190520;R-HSA-8877308;R-HSA-191737;R-HSA-8847544;R-HSA-8875320" R-HSA-140837,"Intrinsic Pathway of Fibrin Clot Formation",1,33,0.0022490288284604375,0.7827179125105309,0.7827179125105309,3,24,0.001851566116340071,9606,Homo sapiens,"SERPING1","","R-HSA-158357;R-HSA-9650473;R-HSA-158399" R-HSA-425410,"Metal ion SLC transporters",1,33,0.0022490288284604375,0.7827179125105309,0.7827179125105309,2,20,0.0015429717636167258,9606,Homo sapiens,"SLC40A1","","R-HSA-904830;R-HSA-442368" R-HSA-187037,"Signaling by NTRK1 (TRKA)",5,143,0.00974579158999523,0.7894857277418913,0.7894857277418913,4,101,0.007792007406264466,9606,Homo sapiens,"DUSP4;FOSL1;POC1A;F3","","R-HSA-9621042;R-HSA-9031624;R-HSA-203797;R-HSA-9621035" R-HSA-948021,"Transport to the Golgi and subsequent modification",8,219,0.014925373134328358,0.7923787619587743,0.7923787619587743,5,60,0.004628915290850177,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;MAN1C1;TUBB4B","","R-HSA-964830;R-HSA-964825;R-HSA-6809006;R-HSA-6809003;R-HSA-964737" R-HSA-5602358,"Diseases associated with the TLR signaling cascade",1,34,0.002317181217201663,0.7925514422376141,0.7925514422376141,4,15,0.0011572288227125443,9606,Homo sapiens,"CD14","","R-HSA-5602353;R-HSA-5602672;R-HSA-5602383;R-HSA-5602606" R-HSA-5260271,"Diseases of Immune System",1,34,0.002317181217201663,0.7925514422376141,0.7925514422376141,4,15,0.0011572288227125443,9606,Homo sapiens,"CD14","","R-HSA-5602353;R-HSA-5602672;R-HSA-5602383;R-HSA-5602606" R-HSA-5654732,"Negative regulation of FGFR3 signaling",1,34,0.002317181217201663,0.7925514422376141,0.7925514422376141,3,14,0.001080080234531708,9606,Homo sapiens,"FGF5","","R-HSA-5654679;R-HSA-5654565;R-HSA-5654730" R-HSA-73614,"Pyrimidine salvage",1,34,0.002317181217201663,0.7925514422376141,0.7925514422376141,1,10,7.714858818083629E-4,9606,Homo sapiens,"TK1","","R-HSA-73632" R-HSA-166016,"Toll Like Receptor 4 (TLR4) Cascade",5,144,0.009813943978736455,0.794403880490241,0.794403880490241,47,95,0.007329115877179448,9606,Homo sapiens,"DUSP4;POC1A;CD14;BIRC3;MAP2K6","","R-HSA-166082;R-HSA-2201316;R-HSA-2569057;R-HSA-166091;R-HSA-2562541;R-HSA-2201322;R-HSA-937029;R-HSA-166286;R-HSA-166284;R-HSA-2559414;R-HSA-168915;R-HSA-166038;R-HSA-2262775;R-HSA-5362500;R-HSA-203797;R-HSA-936985;R-HSA-166362;R-HSA-166363;R-HSA-166168;R-HSA-450333;R-HSA-166041;R-HSA-2262777;R-HSA-2201338;R-HSA-168921;R-HSA-166175;R-HSA-936941;R-HSA-2562564;R-HSA-166119;R-HSA-166245;R-HSA-5362486;R-HSA-2559439;R-HSA-450346;R-HSA-2201293;R-HSA-937059;R-HSA-937022;R-HSA-450358;R-HSA-169719;R-HSA-936952;R-HSA-2559568;R-HSA-2213017;R-HSA-937079;R-HSA-936951;R-HSA-166072;R-HSA-166271;R-HSA-937075;R-HSA-936947;R-HSA-450296" R-HSA-174084,"Autodegradation of Cdh1 by Cdh1:APC/C",2,64,0.004361752879438424,0.7950346277962883,0.7950346277962883,2,2,1.5429717636167257E-4,9606,Homo sapiens,"UBE2S;UBE2C","","R-HSA-174058;R-HSA-174057" R-HSA-5655253,"Signaling by FGFR2 in disease",2,64,0.004361752879438424,0.7950346277962883,0.7950346277962883,16,28,0.002160160469063416,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654748;R-HSA-5655323;R-HSA-5655320;R-HSA-2077424;R-HSA-2033488;R-HSA-2033486;R-HSA-5655268;R-HSA-2077421;R-HSA-5655301;R-HSA-5655233;R-HSA-5655343;R-HSA-5655245;R-HSA-5655339;R-HSA-2033474;R-HSA-5655241;R-HSA-2033472" R-HSA-5654708,"Downstream signaling of activated FGFR3",1,35,0.002385333605942888,0.8019405627864183,0.8019405627864183,22,23,0.0017744175281592346,9606,Homo sapiens,"FGF5","","R-HSA-5654646;R-HSA-5654647;R-HSA-5654709;R-HSA-5654643;R-HSA-5654224;R-HSA-5654640;R-HSA-5654416;R-HSA-5654641;R-HSA-5654705;R-HSA-5654623;R-HSA-5654631;R-HSA-5654148;R-HSA-5654628;R-HSA-8941628;R-HSA-5654625;R-HSA-5654222;R-HSA-5654637;R-HSA-5654413;R-HSA-5654634;R-HSA-5654408;R-HSA-5654633;R-HSA-5654409" R-HSA-9665686,"Signaling by ERBB2 TMD/JMD mutants",1,35,0.002385333605942888,0.8019405627864183,0.8019405627864183,6,13,0.0010029316463508718,9606,Homo sapiens,"BTC","","R-HSA-9665699;R-HSA-9665697;R-HSA-9665701;R-HSA-9665700;R-HSA-9665705;R-HSA-9665709" R-HSA-112399,"IRS-mediated signalling",2,65,0.00442990526817965,0.8020325181831718,0.8020325181831718,1,9,6.943372936275266E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-109699" R-HSA-975871,"MyD88 cascade initiated on plasma membrane",3,94,0.006406324541675185,0.8089593617424103,0.8089593617424103,4,58,0.004474618114488505,9606,Homo sapiens,"DUSP4;POC1A;MAP2K6","","R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-168176,"Toll Like Receptor 5 (TLR5) Cascade",3,94,0.006406324541675185,0.8089593617424103,0.8089593617424103,4,59,0.004551766702669341,9606,Homo sapiens,"DUSP4;POC1A;MAP2K6","","R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-168142,"Toll Like Receptor 10 (TLR10) Cascade",3,94,0.006406324541675185,0.8089593617424103,0.8089593617424103,4,59,0.004551766702669341,9606,Homo sapiens,"DUSP4;POC1A;MAP2K6","","R-HSA-203797;R-HSA-450333;R-HSA-450346;R-HSA-450296" R-HSA-6806667,"Metabolism of fat-soluble vitamins",3,94,0.006406324541675185,0.8089593617424103,0.8089593617424103,1,34,0.002623051998148434,9606,Homo sapiens,"AKR1C1;AKR1C3","","R-HSA-2855252" R-HSA-194068,"Bile acid and bile salt metabolism",4,121,0.00824643903768827,0.8095754994457025,0.8095754994457025,6,94,0.007251967288998611,9606,Homo sapiens,"AKR1C1;AKR1C3;AKR1C2","","R-HSA-192160;R-HSA-193841;R-HSA-192036;R-HSA-193781;R-HSA-193800;R-HSA-193758" R-HSA-1250196,"SHC1 events in ERBB2 signaling",1,36,0.0024534859946841138,0.8109053301298484,0.8109053301298484,4,6,4.6289152908501776E-4,9606,Homo sapiens,"BTC","","R-HSA-1250195;R-HSA-1250486;R-HSA-1963578;R-HSA-1250463" R-HSA-9008059,"Interleukin-37 signaling",1,36,0.0024534859946841138,0.8109053301298484,0.8109053301298484,4,14,0.001080080234531708,9606,Homo sapiens,"IL18R1","","R-HSA-9008684;R-HSA-9008577;R-HSA-8848335;R-HSA-9009072" R-HSA-380972,"Energy dependent regulation of mTOR by LKB1-AMPK",1,36,0.0024534859946841138,0.8109053301298484,0.8109053301298484,2,7,5.40040117265854E-4,9606,Homo sapiens,"RRAGD","","R-HSA-447074;R-HSA-380979" R-HSA-8863795,"Downregulation of ERBB2 signaling",1,36,0.0024534859946841138,0.8109053301298484,0.8109053301298484,2,14,0.001080080234531708,9606,Homo sapiens,"BTC","","R-HSA-1963563;R-HSA-8863804" R-HSA-936440,"Negative regulators of DDX58/IFIH1 signaling",1,36,0.0024534859946841138,0.8109053301298484,0.8109053301298484,1,13,0.0010029316463508718,9606,Homo sapiens,"TNFAIP3","","R-HSA-937337" R-HSA-2022090,"Assembly of collagen fibrils and other multimeric structures",2,67,0.0045662100456621,0.8153946349819563,0.8153946349819563,4,26,0.0020058632927017436,9606,Homo sapiens,"MMP1;LOXL3","","R-HSA-2213200;R-HSA-2022141;R-HSA-2395340;R-HSA-2002466" R-HSA-182971,"EGFR downregulation",1,37,0.002521638383425339,0.8194648964026972,0.8194648964026972,18,22,0.0016972689399783983,9606,Homo sapiens,"BTC","","R-HSA-8867047;R-HSA-183072;R-HSA-8867044;R-HSA-8867041;R-HSA-182986;R-HSA-183051;R-HSA-8951490;R-HSA-182990;R-HSA-183055;R-HSA-183084;R-HSA-183058;R-HSA-182994;R-HSA-183089;R-HSA-182993;R-HSA-183002;R-HSA-183067;R-HSA-182969;R-HSA-183036" R-HSA-8956321,"Nucleotide salvage",2,68,0.004634362434403326,0.8217686925162998,0.8217686925162998,3,21,0.001620120351797562,9606,Homo sapiens,"PNP;TK1","","R-HSA-112033;R-HSA-73632;R-HSA-112034" R-HSA-1442490,"Collagen degradation",2,69,0.004702514823144551,0.8279446116166882,0.8279446116166882,10,34,0.002623051998148434,9606,Homo sapiens,"MMP1","","R-HSA-1454822;R-HSA-1474197;R-HSA-1474213;R-HSA-1454757;R-HSA-1564179;R-HSA-1564143;R-HSA-1564142;R-HSA-2168923;R-HSA-1564169;R-HSA-1564120" R-HSA-2428928,"IRS-related events triggered by IGF1R",2,69,0.004702514823144551,0.8279446116166882,0.8279446116166882,1,12,9.257830581700355E-4,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-109699" R-HSA-8943724,"Regulation of PTEN gene transcription",2,70,0.004770667211885776,0.8339272570573159,0.8339272570573159,4,15,0.0011572288227125443,9606,Homo sapiens,"RRAGD;EZH2","","R-HSA-8944104;R-HSA-8944457;R-HSA-8943817;R-HSA-8944454" R-HSA-373755,"Semaphorin interactions",2,70,0.004770667211885776,0.8339272570573159,0.8339272570573159,2,40,0.0030859435272334516,9606,Homo sapiens,"CD72;PLXNC1","","R-HSA-373748;R-HSA-434989" R-HSA-5654726,"Negative regulation of FGFR1 signaling",1,39,0.00265794316090779,0.8354407573050067,0.8354407573050067,3,15,0.0011572288227125443,9606,Homo sapiens,"FGF5","","R-HSA-5654672;R-HSA-5654560;R-HSA-5654673" R-HSA-1855204,"Synthesis of IP3 and IP4 in the cytosol",1,39,0.00265794316090779,0.8354407573050067,0.8354407573050067,1,12,9.257830581700355E-4,9606,Homo sapiens,"PLCB4","","R-HSA-1855177" R-HSA-9022692,"Regulation of MECP2 expression and activity",1,39,0.00265794316090779,0.8354407573050067,0.8354407573050067,1,14,0.001080080234531708,9606,Homo sapiens,"AURKB","","R-HSA-9023132" R-HSA-6804758,"Regulation of TP53 Activity through Acetylation",1,39,0.00265794316090779,0.8354407573050067,0.8354407573050067,1,14,0.001080080234531708,9606,Homo sapiens,"MAP2K6","","R-HSA-8877691" R-HSA-4791275,"Signaling by WNT in cancer",1,39,0.00265794316090779,0.8354407573050067,0.8354407573050067,1,16,0.0012343774108933806,9606,Homo sapiens,"PORCN","","R-HSA-5340560" R-HSA-112043,"PLC beta mediated events",2,71,0.004838819600627002,0.8397214589662099,0.8397214589662099,5,32,0.002468754821786761,9606,Homo sapiens,"PLCB4;KPNA2","","R-HSA-112037;R-HSA-9619127;R-HSA-111879;R-HSA-112282;R-HSA-111870" R-HSA-936837,"Ion transport by P-type ATPases",2,71,0.004838819600627002,0.8397214589662099,0.8397214589662099,2,14,0.001080080234531708,9606,Homo sapiens,"ATP8B4","","R-HSA-947591;R-HSA-939763" R-HSA-8848021,"Signaling by PTK6",2,71,0.004838819600627002,0.8397214589662099,0.8397214589662099,4,53,0.004088875173584324,9606,Homo sapiens,"BTC;CDK2","","R-HSA-8848005;R-HSA-8848436;R-HSA-8848414;R-HSA-8847995" R-HSA-9006927,"Signaling by Non-Receptor Tyrosine Kinases",2,71,0.004838819600627002,0.8397214589662099,0.8397214589662099,4,53,0.004088875173584324,9606,Homo sapiens,"BTC;CDK2","","R-HSA-8848005;R-HSA-8848436;R-HSA-8848414;R-HSA-8847995" R-HSA-112314,"Neurotransmitter receptors and postsynaptic signal transmission",8,232,0.01581135418796429,0.8399063916415443,0.8399063916415443,5,109,0.008409196111711155,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B;KPNA2","","R-HSA-9610627;R-HSA-9619542;R-HSA-9619127;R-HSA-9610408;R-HSA-112282" R-HSA-8986944,"Transcriptional Regulation by MECP2",3,100,0.006815238874122538,0.8404938289492747,0.8404938289492747,3,77,0.005940441289924395,9606,Homo sapiens,"GPRIN1;AURKB","","R-HSA-9021946;R-HSA-9023132;R-HSA-9021948" R-HSA-156584,"Cytosolic sulfonation of small molecules",2,72,0.0049069719893682275,0.8453320060395675,0.8453320060395675,7,24,0.001851566116340071,9606,Homo sapiens,"SULT1A1","","R-HSA-158849;R-HSA-176646;R-HSA-158468;R-HSA-176474;R-HSA-176585;R-HSA-158860;R-HSA-176669" R-HSA-112040,"G-protein mediated events",2,72,0.0049069719893682275,0.8453320060395675,0.8453320060395675,5,41,0.003163092115414288,9606,Homo sapiens,"PLCB4;KPNA2","","R-HSA-112037;R-HSA-9619127;R-HSA-111879;R-HSA-112282;R-HSA-111870" R-HSA-2428924,"IGF1R signaling cascade",2,72,0.0049069719893682275,0.8453320060395675,0.8453320060395675,1,17,0.001311525999074217,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-109699" R-HSA-74751,"Insulin receptor signalling cascade",2,72,0.0049069719893682275,0.8453320060395675,0.8453320060395675,1,25,0.0019287147045209073,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-109699" R-HSA-392154,"Nitric oxide stimulates guanylate cyclase",1,41,0.0027942479383902406,0.8500047863997757,0.8500047863997757,2,7,5.40040117265854E-4,9606,Homo sapiens,"GUCY1A2","","R-HSA-392143;R-HSA-392152" R-HSA-73887,"Death Receptor Signalling",5,157,0.010699925032372385,0.850415042401315,0.850415042401315,12,90,0.006943372936275266,9606,Homo sapiens,"BCL2L11;ARHGEF3;TNFAIP3;ECT2;BIRC3","","R-HSA-205075;R-HSA-140978;R-HSA-5357776;R-HSA-5357904;R-HSA-5693108;R-HSA-5357845;R-HSA-5357860;R-HSA-5357780;R-HSA-5693055;R-HSA-5357928;R-HSA-205039;R-HSA-5357757" R-HSA-2404192,"Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)",2,73,0.004975124378109453,0.8507636394369162,0.8507636394369162,1,19,0.0014658231754358896,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-109699" R-HSA-2219530,"Constitutive Signaling by Aberrant PI3K in Cancer",3,103,0.007019696040346214,0.8545032916906562,0.8545032916906562,1,2,1.5429717636167257E-4,9606,Homo sapiens,"BTC;FGF5;FGF7","","R-HSA-2400009" R-HSA-6785807,"Interleukin-4 and Interleukin-13 signaling",7,211,0.014380154024398555,0.8551569255203171,0.8551569255203171,4,46,0.003548835056318469,9606,Homo sapiens,"TG;MMP1;BIRC5;IL6R","","R-HSA-6785895;R-HSA-6790022;R-HSA-6790036;R-HSA-6789615" R-HSA-5654687,"Downstream signaling of activated FGFR1",1,42,0.0028624003271314658,0.8567967421361526,0.8567967421361526,23,24,0.001851566116340071,9606,Homo sapiens,"FGF5","","R-HSA-5654582;R-HSA-5654167;R-HSA-5654165;R-HSA-5654578;R-HSA-5654591;R-HSA-5654586;R-HSA-5654587;R-HSA-5654584;R-HSA-5654392;R-HSA-5654692;R-HSA-5654596;R-HSA-5654149;R-HSA-5654597;R-HSA-5654594;R-HSA-5654690;R-HSA-5656064;R-HSA-5654592;R-HSA-5654575;R-HSA-5654573;R-HSA-5654571;R-HSA-5654600;R-HSA-8941623;R-HSA-5654569" R-HSA-8853338,"Signaling by FGFR3 point mutants in cancer",1,42,0.0028624003271314658,0.8567967421361526,0.8567967421361526,13,19,0.0014658231754358896,9606,Homo sapiens,"FGF5","","R-HSA-5655285;R-HSA-5655315;R-HSA-5655262;R-HSA-5655295;R-HSA-5655289;R-HSA-5655270;R-HSA-2077420;R-HSA-2012074;R-HSA-2012073;R-HSA-5655247;R-HSA-5655244;R-HSA-5655277;R-HSA-5655243" R-HSA-5655332,"Signaling by FGFR3 in disease",1,42,0.0028624003271314658,0.8567967421361526,0.8567967421361526,13,28,0.002160160469063416,9606,Homo sapiens,"FGF5","","R-HSA-5655285;R-HSA-5655315;R-HSA-5655262;R-HSA-5655295;R-HSA-5655289;R-HSA-5655270;R-HSA-2077420;R-HSA-2012074;R-HSA-2012073;R-HSA-5655247;R-HSA-5655244;R-HSA-5655277;R-HSA-5655243" R-HSA-163560,"Triglyceride catabolism",1,42,0.0028624003271314658,0.8567967421361526,0.8567967421361526,1,17,0.001311525999074217,9606,Homo sapiens,"FABP5","","R-HSA-5334794" R-HSA-8964043,"Plasma lipoprotein clearance",1,42,0.0028624003271314658,0.8567967421361526,0.8567967421361526,2,35,0.00270020058632927,9606,Homo sapiens,"LSR","","R-HSA-8933258;R-HSA-8933292" R-HSA-1474290,"Collagen formation",3,104,0.007087848429087439,0.8589285302723049,0.8589285302723049,5,77,0.005940441289924395,9606,Homo sapiens,"ADAMTS3;MMP1;LOXL3","","R-HSA-2213200;R-HSA-2002428;R-HSA-2022141;R-HSA-2395340;R-HSA-2002466" R-HSA-8853659,"RET signaling",1,43,0.0029305527158726913,0.8632815833288152,0.8632815833288152,20,24,0.001851566116340071,9606,Homo sapiens,"CDC25C","","R-HSA-8853734;R-HSA-8854981;R-HSA-8855747;R-HSA-8853762;R-HSA-8853793;R-HSA-8855617;R-HSA-8853792;R-HSA-8853774;R-HSA-8855564;R-HSA-8855915;R-HSA-8853737;R-HSA-8853800;R-HSA-8855508;R-HSA-8854899;R-HSA-8854897;R-HSA-8853745;R-HSA-8854908;R-HSA-8853755;R-HSA-8853753;R-HSA-8854905" R-HSA-381771,"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)",1,43,0.0029305527158726913,0.8632815833288152,0.8632815833288152,1,7,5.40040117265854E-4,9606,Homo sapiens,"SPC25","","R-HSA-400459" R-HSA-111933,"Calmodulin induced events",1,43,0.0029305527158726913,0.8632815833288152,0.8632815833288152,2,23,0.0017744175281592346,9606,Homo sapiens,"KPNA2","","R-HSA-9619127;R-HSA-112282" R-HSA-111997,"CaM pathway",1,43,0.0029305527158726913,0.8632815833288152,0.8632815833288152,2,24,0.001851566116340071,9606,Homo sapiens,"KPNA2","","R-HSA-9619127;R-HSA-112282" R-HSA-8982491,"Glycogen metabolism",1,43,0.0029305527158726913,0.8632815833288152,0.8632815833288152,2,39,0.003008794939052615,9606,Homo sapiens,"PHKG1","","R-HSA-71541;R-HSA-453337" R-HSA-1296072,"Voltage gated Potassium channels",1,44,0.002998705104613917,0.869473177314587,0.869473177314587,1,1,7.714858818083629E-5,9606,Homo sapiens,"KCND3","","R-HSA-1296127" R-HSA-74217,"Purine salvage",1,44,0.002998705104613917,0.869473177314587,0.869473177314587,2,11,8.486344699891992E-4,9606,Homo sapiens,"PNP","","R-HSA-112033;R-HSA-112034" R-HSA-2046106,"alpha-linolenic acid (ALA) metabolism",1,45,0.003066857493355142,0.8753847661540581,0.8753847661540581,1,15,0.0011572288227125443,9606,Homo sapiens,"ELOVL3","","R-HSA-2046088" R-HSA-3906995,"Diseases associated with O-glycosylation of proteins",2,78,0.00531588632181558,0.8754000730863318,0.8754000730863318,1,9,6.943372936275266E-4,9606,Homo sapiens,"ADAMTS4;ADAMTS3","","R-HSA-6785565" R-HSA-193704,"p75 NTR receptor-mediated signalling",3,109,0.007428610372793566,0.8793275511150536,0.8793275511150536,2,50,0.0038574294090418146,9606,Homo sapiens,"BCL2L11;ARHGEF3;ECT2","","R-HSA-205075;R-HSA-205039" R-HSA-1660661,"Sphingolipid de novo biosynthesis",2,79,0.005384038710556805,0.8798545083182604,0.8798545083182604,6,30,0.0023144576454250886,9606,Homo sapiens,"CERS4;PPM1L","","R-HSA-429732;R-HSA-429730;R-HSA-429699;R-HSA-429683;R-HSA-429694;R-HSA-428185" R-HSA-75105,"Fatty acyl-CoA biosynthesis",2,79,0.005384038710556805,0.8798545083182604,0.8798545083182604,3,24,0.001851566116340071,9606,Homo sapiens,"DEPDC1B;ELOVL3","","R-HSA-548814;R-HSA-548815;R-HSA-548800" R-HSA-9664565,"Signaling by ERBB2 KD Mutants",1,46,0.0031350098820963675,0.8810289947852642,0.8810289947852642,6,17,0.001311525999074217,9606,Homo sapiens,"BTC","","R-HSA-9664976;R-HSA-9664567;R-HSA-9664983;R-HSA-9664950;R-HSA-9664991;R-HSA-9664588" R-HSA-168276,"NS1 Mediated Effects on Host Pathways",1,46,0.0031350098820963675,0.8810289947852642,0.8810289947852642,2,6,4.6289152908501776E-4,9606,Homo sapiens,"KPNA2","","R-HSA-1176059;R-HSA-6791035" R-HSA-166520,"Signaling by NTRKs",5,166,0.011313296531043413,0.8812796157768316,0.8812796157768316,4,163,0.012575219873476316,9606,Homo sapiens,"DUSP4;FOSL1;POC1A;F3","","R-HSA-9621042;R-HSA-9031624;R-HSA-203797;R-HSA-9621035" R-HSA-9009391,"Extra-nuclear estrogen signaling",3,110,0.0074967627615347915,0.8830784598819748,0.8830784598819748,5,38,0.002931646350871779,9606,Homo sapiens,"BTC;MMP1;S1PR3","","R-HSA-9624272;R-HSA-9625813;R-HSA-9625482;R-HSA-9625465;R-HSA-9625487" R-HSA-400508,"Incretin synthesis, secretion, and inactivation",1,47,0.0032031622708375927,0.8864179379116071,0.8864179379116071,2,14,0.001080080234531708,9606,Homo sapiens,"SPC25","","R-HSA-400496;R-HSA-400459" R-HSA-1251985,"Nuclear signaling by ERBB4",1,47,0.0032031622708375927,0.8864179379116071,0.8864179379116071,1,34,0.002623051998148434,9606,Homo sapiens,"BTC","","R-HSA-1251992" R-HSA-1643713,"Signaling by EGFR in Cancer",1,47,0.0032031622708375927,0.8864179379116071,0.8864179379116071,1,42,0.003240240703595124,9606,Homo sapiens,"BTC","","R-HSA-1225978" R-HSA-3108214,"SUMOylation of DNA damage response and repair proteins",2,81,0.005520343488039256,0.8883252465970919,0.8883252465970919,3,24,0.001851566116340071,9606,Homo sapiens,"BLM;BRCA1","","R-HSA-2997709;R-HSA-4568914;R-HSA-2997616" R-HSA-6811438,"Intra-Golgi traffic",1,48,0.003271314659578818,0.8915631256807053,0.8915631256807053,2,10,7.714858818083629E-4,9606,Homo sapiens,"MAN1C1","","R-HSA-8847635;R-HSA-8847544" R-HSA-1227990,"Signaling by ERBB2 in Cancer",1,48,0.003271314659578818,0.8915631256807053,0.8915631256807053,12,62,0.00478321246721185,9606,Homo sapiens,"BTC","","R-HSA-9665699;R-HSA-9665697;R-HSA-9664976;R-HSA-9664567;R-HSA-9664983;R-HSA-9664950;R-HSA-9665701;R-HSA-9665700;R-HSA-9665705;R-HSA-9664991;R-HSA-9665709;R-HSA-9664588" R-HSA-1839124,"FGFR1 mutant receptor activation",1,48,0.003271314659578818,0.8915631256807053,0.8915631256807053,2,25,0.0019287147045209073,9606,Homo sapiens,"FGF5","","R-HSA-2023455;R-HSA-2023451" R-HSA-111996,"Ca-dependent events",1,48,0.003271314659578818,0.8915631256807053,0.8915631256807053,2,27,0.00208301188088258,9606,Homo sapiens,"KPNA2","","R-HSA-9619127;R-HSA-112282" R-HSA-2022377,"Metabolism of Angiotensinogen to Angiotensins",1,48,0.003271314659578818,0.8915631256807053,0.8915631256807053,1,20,0.0015429717636167258,9606,Homo sapiens,"CPB1","","R-HSA-2028294" R-HSA-1169408,"ISG15 antiviral mechanism",2,83,0.005656648265521706,0.8962394698504786,0.8962394698504786,3,16,0.0012343774108933806,9606,Homo sapiens,"KPNA2;IFIT1","","R-HSA-1678841;R-HSA-1176059;R-HSA-1169406" R-HSA-5633008,"TP53 Regulates Transcription of Cell Death Genes",2,83,0.005656648265521706,0.8962394698504786,0.8962394698504786,2,68,0.005246103996296868,9606,Homo sapiens,"BIRC5","","R-HSA-6797766;R-HSA-6797763" R-HSA-165159,"MTOR signalling",1,49,0.0033394670483200438,0.8964755682085119,0.8964755682085119,14,28,0.002160160469063416,9606,Homo sapiens,"RRAGD","","R-HSA-5653974;R-HSA-8952716;R-HSA-447074;R-HSA-5653968;R-HSA-377186;R-HSA-5672828;R-HSA-5672824;R-HSA-165680;R-HSA-5653957;R-HSA-165718;R-HSA-380979;R-HSA-5672843;R-HSA-165692;R-HSA-8952726" R-HSA-8854214,"TBC/RABGAPs",1,49,0.0033394670483200438,0.8964755682085119,0.8964755682085119,1,14,0.001080080234531708,9606,Homo sapiens,"RAB33A","","R-HSA-8854612" R-HSA-8856825,"Cargo recognition for clathrin-mediated endocytosis",3,115,0.007837524705240918,0.9003160011354199,0.9003160011354199,7,14,0.001080080234531708,9606,Homo sapiens,"BTC;AGTR1;STON2","","R-HSA-8863463;R-HSA-8866279;R-HSA-8863727;R-HSA-8866269;R-HSA-8863723;R-HSA-8866283;R-HSA-8863721" R-HSA-163125,"Post-translational modification: synthesis of GPI-anchored proteins",3,115,0.007837524705240918,0.9003160011354199,0.9003160011354199,1,16,0.0012343774108933806,9606,Homo sapiens,"RTN4RL1;RAET1G","","R-HSA-8940388" R-HSA-416482,"G alpha (12/13) signalling events",2,85,0.0057929530430041575,0.9036292460572579,0.9036292460572579,1,14,0.001080080234531708,9606,Homo sapiens,"ARHGEF3;ECT2","","R-HSA-419166" R-HSA-383280,"Nuclear Receptor transcription pathway",2,86,0.005861105431745383,0.907137128665634,0.907137128665634,2,2,1.5429717636167257E-4,9606,Homo sapiens,"NR0B1","","R-HSA-382096;R-HSA-376419" R-HSA-6783783,"Interleukin-10 signaling",2,86,0.005861105431745383,0.907137128665634,0.907137128665634,1,15,0.0011572288227125443,9606,Homo sapiens,"IL1R2","","R-HSA-8937656" R-HSA-8878159,"Transcriptional regulation by RUNX3",3,118,0.008041981871464595,0.9095257463416428,0.9095257463416428,3,47,0.0036259836444993056,9606,Homo sapiens,"BCL2L11;TCF7","","R-HSA-8952232;R-HSA-8952226;R-HSA-8951428" R-HSA-5654738,"Signaling by FGFR2",2,88,0.005997410209227834,0.913797478997212,0.913797478997212,30,46,0.003548835056318469,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654614;R-HSA-5654615;R-HSA-5654612;R-HSA-5654677;R-HSA-5654608;R-HSA-5654622;R-HSA-190408;R-HSA-5654620;R-HSA-5654618;R-HSA-190413;R-HSA-5656070;R-HSA-5654406;R-HSA-5654407;R-HSA-5654404;R-HSA-5654402;R-HSA-5654147;R-HSA-5654607;R-HSA-5654159;R-HSA-5654605;R-HSA-5654157;R-HSA-5654603;R-HSA-5654729;R-HSA-5654399;R-HSA-5654397;R-HSA-190258;R-HSA-5654562;R-HSA-190260;R-HSA-8941618;R-HSA-5654701;R-HSA-5654697" R-HSA-5654741,"Signaling by FGFR3",1,53,0.003612076603284945,0.9140011695901747,0.9140011695901747,27,43,0.0033173892917759606,9606,Homo sapiens,"FGF5","","R-HSA-5654679;R-HSA-5654224;R-HSA-5654416;R-HSA-5654623;R-HSA-5654148;R-HSA-5654222;R-HSA-5654413;R-HSA-5654730;R-HSA-5654408;R-HSA-5654409;R-HSA-5654646;R-HSA-5654647;R-HSA-5654709;R-HSA-5654643;R-HSA-5654640;R-HSA-5654641;R-HSA-5654705;R-HSA-5654631;R-HSA-5654628;R-HSA-5654565;R-HSA-8941628;R-HSA-190388;R-HSA-5654625;R-HSA-190261;R-HSA-5654637;R-HSA-5654634;R-HSA-5654633" R-HSA-1489509,"DAG and IP3 signaling",1,53,0.003612076603284945,0.9140011695901747,0.9140011695901747,2,28,0.002160160469063416,9606,Homo sapiens,"KPNA2","","R-HSA-9619127;R-HSA-112282" R-HSA-5683826,"Surfactant metabolism",1,53,0.003612076603284945,0.9140011695901747,0.9140011695901747,1,29,0.0022373090572442526,9606,Homo sapiens,"LMCD1","","R-HSA-5683888" R-HSA-69613,"p53-Independent G1/S DNA damage checkpoint",1,54,0.0036802289920261706,0.9178984183498741,0.9178984183498741,4,4,3.0859435272334514E-4,9606,Homo sapiens,"CDC25A","","R-HSA-69600;R-HSA-69604;R-HSA-69608;R-HSA-69598" R-HSA-69601,"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A",1,54,0.0036802289920261706,0.9178984183498741,0.9178984183498741,4,4,3.0859435272334514E-4,9606,Homo sapiens,"CDC25A","","R-HSA-69600;R-HSA-69604;R-HSA-69608;R-HSA-69598" R-HSA-69610,"p53-Independent DNA Damage Response",1,54,0.0036802289920261706,0.9178984183498741,0.9178984183498741,4,4,3.0859435272334514E-4,9606,Homo sapiens,"CDC25A","","R-HSA-69600;R-HSA-69604;R-HSA-69608;R-HSA-69598" R-HSA-382556,"ABC-family proteins mediated transport",3,122,0.008314591426429496,0.9206048140802054,0.9206048140802054,3,27,0.00208301188088258,9606,Homo sapiens,"ABCA6;ABCA8","","R-HSA-1369028;R-HSA-1467457;R-HSA-1369052" R-HSA-8854050,"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis",1,55,0.0037483813807673958,0.9216193023446186,0.9216193023446186,3,6,4.6289152908501776E-4,9606,Homo sapiens,"AURKB;AURKA","","R-HSA-8854044;R-HSA-8854041;R-HSA-8853496" R-HSA-445355,"Smooth Muscle Contraction",1,55,0.0037483813807673958,0.9216193023446186,0.9216193023446186,2,11,8.486344699891992E-4,9606,Homo sapiens,"GUCY1A2","","R-HSA-392143;R-HSA-392152" R-HSA-2046104,"alpha-linolenic (omega3) and linoleic (omega6) acid metabolism",1,55,0.0037483813807673958,0.9216193023446186,0.9216193023446186,2,25,0.0019287147045209073,9606,Homo sapiens,"ELOVL3","","R-HSA-2046094;R-HSA-2046088" R-HSA-5632684,"Hedgehog 'on' state",2,92,0.006270019764192735,0.9257953910305292,0.9257953910305292,14,37,0.0028544977626909426,9606,Homo sapiens,"GLI1","","R-HSA-5635861;R-HSA-5635860;R-HSA-5635859;R-HSA-5635868;R-HSA-5635864;R-HSA-5635845;R-HSA-5635846;R-HSA-5635841;R-HSA-5610723;R-HSA-5635843;R-HSA-5635842;R-HSA-5635853;R-HSA-5635848;R-HSA-5635850" R-HSA-168898,"Toll-like Receptor Cascades",5,184,0.01254003952838547,0.9269802328343706,0.9269802328343706,53,182,0.014041043048912205,9606,Homo sapiens,"DUSP4;POC1A;CD14;BIRC3;MAP2K6","","R-HSA-166286;R-HSA-166284;R-HSA-2559414;R-HSA-166038;R-HSA-5362500;R-HSA-203797;R-HSA-936985;R-HSA-166168;R-HSA-450333;R-HSA-166041;R-HSA-166175;R-HSA-2562564;R-HSA-450346;R-HSA-937022;R-HSA-450358;R-HSA-2213017;R-HSA-8869694;R-HSA-166072;R-HSA-166082;R-HSA-2201316;R-HSA-2569057;R-HSA-166091;R-HSA-2562541;R-HSA-2201322;R-HSA-2559468;R-HSA-937029;R-HSA-2559464;R-HSA-9014342;R-HSA-168915;R-HSA-2262775;R-HSA-166362;R-HSA-166363;R-HSA-2262777;R-HSA-2201338;R-HSA-168921;R-HSA-936941;R-HSA-166119;R-HSA-166245;R-HSA-5362486;R-HSA-2559439;R-HSA-2201293;R-HSA-937059;R-HSA-168950;R-HSA-169719;R-HSA-168951;R-HSA-936952;R-HSA-2559568;R-HSA-937079;R-HSA-936951;R-HSA-166271;R-HSA-937075;R-HSA-936947;R-HSA-450296" R-HSA-6799198,"Complex I biogenesis",1,57,0.003884686158249847,0.9285634959759786,0.9285634959759786,5,13,0.0010029316463508718,9606,Homo sapiens,"E2F1","","R-HSA-6799191;R-HSA-6799202;R-HSA-6799197;R-HSA-6799196;R-HSA-6799179" R-HSA-9604323,"Negative regulation of NOTCH4 signaling",1,57,0.003884686158249847,0.9285634959759786,0.9285634959759786,1,6,4.6289152908501776E-4,9606,Homo sapiens,"TACC3","","R-HSA-9604675" R-HSA-380108,"Chemokine receptors bind chemokines",1,57,0.003884686158249847,0.9285634959759786,0.9285634959759786,1,19,0.0014658231754358896,9606,Homo sapiens,"ACKR3","","R-HSA-374214" R-HSA-2453902,"The canonical retinoid cycle in rods (twilight vision)",1,57,0.003884686158249847,0.9285634959759786,0.9285634959759786,1,25,0.0019287147045209073,9606,Homo sapiens,"RDH10","","R-HSA-74872" R-HSA-6811558,"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling",3,126,0.008587200981394398,0.9304315891468994,0.9304315891468994,1,7,5.40040117265854E-4,9606,Homo sapiens,"BTC;FGF5;FGF7","","R-HSA-2316434" R-HSA-1226099,"Signaling by FGFR in disease",2,94,0.006406324541675185,0.9311864566414254,0.9311864566414254,41,106,0.008177750347168647,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-2023455;R-HSA-2023451;R-HSA-5655315;R-HSA-5655326;R-HSA-5655262;R-HSA-5655263;R-HSA-5654748;R-HSA-5655323;R-HSA-5655320;R-HSA-2033488;R-HSA-2033486;R-HSA-5655301;R-HSA-5655233;R-HSA-5655247;R-HSA-5655244;R-HSA-5655245;R-HSA-2033474;R-HSA-5655243;R-HSA-5655240;R-HSA-5655241;R-HSA-2033472;R-HSA-1839100;R-HSA-5655285;R-HSA-1839098;R-HSA-5655295;R-HSA-1839094;R-HSA-5655290;R-HSA-2077424;R-HSA-5655289;R-HSA-5655270;R-HSA-5655268;R-HSA-2077421;R-HSA-5655269;R-HSA-2077420;R-HSA-2012074;R-HSA-5655266;R-HSA-2012073;R-HSA-5655278;R-HSA-5655343;R-HSA-5655277;R-HSA-5655339" R-HSA-1169410,"Antiviral mechanism by IFN-stimulated genes",2,94,0.006406324541675185,0.9311864566414254,0.9311864566414254,3,31,0.002391606233605925,9606,Homo sapiens,"KPNA2;IFIT1","","R-HSA-1678841;R-HSA-1176059;R-HSA-1169406" R-HSA-8876198,"RAB GEFs exchange GTP for GDP on RABs",2,94,0.006406324541675185,0.9311864566414254,0.9311864566414254,2,21,0.001620120351797562,9606,Homo sapiens,"CDK2;RAB27B","","R-HSA-8877308;R-HSA-8875320" R-HSA-6798695,"Neutrophil degranulation",16,480,0.03271314659578818,0.9314521248932488,0.9314521248932488,10,10,7.714858818083629E-4,9606,Homo sapiens,"POLQ;ATP8B4;TUBB;TUBB4B;PLD1;ATAD3A;GLIPR1;DSN1;PNP;ADGRE5;FABP5;SLPI;MBP;METTL7A;CD14;DOCK2","","R-HSA-6798743;R-HSA-6799350;R-HSA-6798739;R-HSA-6800434;R-HSA-6798751;R-HSA-6798749;R-HSA-6798748;R-HSA-6798747;R-HSA-6800426;R-HSA-6798745" R-HSA-5655302,"Signaling by FGFR1 in disease",1,58,0.003952838546991072,0.9318016826631782,0.9318016826631782,12,35,0.00270020058632927,9606,Homo sapiens,"FGF5","","R-HSA-1839100;R-HSA-2023455;R-HSA-5655269;R-HSA-5655266;R-HSA-2023451;R-HSA-1839098;R-HSA-5655326;R-HSA-5655278;R-HSA-5655263;R-HSA-1839094;R-HSA-5655290;R-HSA-5655240" R-HSA-9007101,"Rab regulation of trafficking",3,129,0.008791658147618075,0.9370541446798487,0.9370541446798487,3,35,0.00270020058632927,9606,Homo sapiens,"CDK2;RAB27B;RAB33A","","R-HSA-8854612;R-HSA-8877308;R-HSA-8875320" R-HSA-5339562,"Uptake and actions of bacterial toxins",1,60,0.004089143324473523,0.9378449447510044,0.9378449447510044,1,65,0.005014658231754359,9606,Homo sapiens,"MAP2K6","","R-HSA-5211405" R-HSA-74752,"Signaling by Insulin receptor",2,97,0.0066107817078988615,0.9385833654514778,0.9385833654514778,1,34,0.002623051998148434,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-109699" R-HSA-8856828,"Clathrin-mediated endocytosis",4,161,0.010972534587337286,0.939436102969361,0.939436102969361,22,34,0.002623051998148434,9606,Homo sapiens,"BTC;CDK2;AGTR1;STON2","","R-HSA-8868071;R-HSA-8863463;R-HSA-8866279;R-HSA-8868230;R-HSA-8863727;R-HSA-8867756;R-HSA-8868236;R-HSA-8863723;R-HSA-8868651;R-HSA-8866283;R-HSA-8867754;R-HSA-8863721;R-HSA-8868072;R-HSA-8868648;R-HSA-8868661;R-HSA-8868660;R-HSA-8868659;R-HSA-8868658;R-HSA-8869438;R-HSA-8866269;R-HSA-8871194;R-HSA-8871193" R-HSA-5610780,"Degradation of GLI1 by the proteasome",1,62,0.004225448101955974,0.9433534142765176,0.9433534142765176,5,6,4.6289152908501776E-4,9606,Homo sapiens,"GLI1","","R-HSA-5610741;R-HSA-5610758;R-HSA-5610742;R-HSA-5610737;R-HSA-5610760" R-HSA-5654736,"Signaling by FGFR1",1,62,0.004225448101955974,0.9433534142765176,0.9433534142765176,29,48,0.003703132232680142,9606,Homo sapiens,"FGF5","","R-HSA-5654167;R-HSA-5654165;R-HSA-5654672;R-HSA-5654673;R-HSA-5654596;R-HSA-5654149;R-HSA-5654597;R-HSA-5654594;R-HSA-5656064;R-HSA-5654592;R-HSA-5654600;R-HSA-190429;R-HSA-5654582;R-HSA-5654578;R-HSA-5654591;R-HSA-5654586;R-HSA-5654587;R-HSA-5654584;R-HSA-5654392;R-HSA-190256;R-HSA-5654692;R-HSA-5654690;R-HSA-5654560;R-HSA-5654511;R-HSA-5654575;R-HSA-5654573;R-HSA-5654571;R-HSA-8941623;R-HSA-5654569" R-HSA-4551638,"SUMOylation of chromatin organization proteins",1,62,0.004225448101955974,0.9433534142765176,0.9433534142765176,2,15,0.0011572288227125443,9606,Homo sapiens,"HIST2H4A;HIST1H4B;HIST1H4L;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E","","R-HSA-4570485;R-HSA-4570496" R-HSA-199418,"Negative regulation of the PI3K/AKT network",3,134,0.0091324200913242,0.9468115050976031,0.9468115050976031,1,10,7.714858818083629E-4,9606,Homo sapiens,"BTC;FGF5;FGF7","","R-HSA-2316434" R-HSA-2219528,"PI3K/AKT Signaling in Cancer",3,134,0.0091324200913242,0.9468115050976031,0.9468115050976031,1,21,0.001620120351797562,9606,Homo sapiens,"BTC;FGF5;FGF7","","R-HSA-2400009" R-HSA-6802957,"Oncogenic MAPK signaling",2,101,0.006883391262863764,0.947278640115911,0.947278640115911,6,46,0.003548835056318469,9606,Homo sapiens,"BCL2L11;POC1A","","R-HSA-6802935;R-HSA-6802934;R-HSA-6802933;R-HSA-6802932;R-HSA-9652816;R-HSA-6802927" R-HSA-2142753,"Arachidonic acid metabolism",4,166,0.011313296531043413,0.948079190251751,0.948079190251751,6,77,0.005940441289924395,9606,Homo sapiens,"EPHX2;AKR1C1;TBXAS1;AKR1C3;PTGES","","R-HSA-76500;R-HSA-2161961;R-HSA-2161660;R-HSA-2161549;R-HSA-2161613;R-HSA-2161614" R-HSA-5578775,"Ion homeostasis",1,64,0.004361752879438424,0.9483743535021205,0.9483743535021205,1,15,0.0011572288227125443,9606,Homo sapiens,"CLIC2","","R-HSA-2855020" R-HSA-1483191,"Synthesis of PC",1,65,0.00442990526817965,0.9507156178741638,0.9507156178741638,1,18,0.0013886745872550533,9606,Homo sapiens,"MFSD2A","","R-HSA-8865637" R-HSA-3299685,"Detoxification of Reactive Oxygen Species",1,65,0.00442990526817965,0.9507156178741638,0.9507156178741638,1,34,0.002623051998148434,9606,Homo sapiens,"SOD2","","R-HSA-3299680" R-HSA-1266738,"Developmental Biology",46,1241,0.0845771144278607,0.9526171958140893,0.9526171958140893,93,537,0.04142879185310909,9606,Homo sapiens,"TUBA1C;TUBB6;TUBA1B;TUBB3;MPZ;HIST1H2AE;HIST1H2AD;PLXNC1;IL6R;H2AFZ;HIST1H2AK;H2AFX;HIST2H2BB;CDC25C;GAP43;RBL1;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST1H2BN;CEBPA;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;ADGRG6;E2F1;MBP;HIST1H3B;MAP2K6;RPL39L;CD72;HIST1H4L;H2BFS;TUBB4B;MAFB;HIST1H4B;KIF4A;CDK2;MYF6;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;EZH2","","R-HSA-5617877;R-HSA-5617492;R-HSA-9618582;R-HSA-8853762;R-HSA-5617874;R-HSA-9618586;R-HSA-1183003;R-HSA-445071;R-HSA-8853774;R-HSA-5617887;R-HSA-8855564;R-HSA-9634433;R-HSA-5617862;R-HSA-445077;R-HSA-5617859;R-HSA-9634442;R-HSA-5617484;R-HSA-5693644;R-HSA-5617486;R-HSA-9634446;R-HSA-9634445;R-HSA-5617483;R-HSA-5617867;R-HSA-5617866;R-HSA-9624112;R-HSA-9617207;R-HSA-8853793;R-HSA-9614773;R-HSA-5617650;R-HSA-8853792;R-HSA-5617661;R-HSA-1183032;R-HSA-9624120;R-HSA-434989;R-HSA-9617087;R-HSA-9614271;R-HSA-8853800;R-HSA-448951;R-HSA-5617641;R-HSA-5617896;R-HSA-5617642;R-HSA-1183058;R-HSA-5617431;R-HSA-8854981;R-HSA-448962;R-HSA-8855747;R-HSA-9616214;R-HSA-448963;R-HSA-8855617;R-HSA-5621010;R-HSA-6810159;R-HSA-9622363;R-HSA-6810158;R-HSA-9622367;R-HSA-9624668;R-HSA-9614787;R-HSA-8855508;R-HSA-9614273;R-HSA-9614790;R-HSA-6810161;R-HSA-8933328;R-HSA-5617676;R-HSA-9014610;R-HSA-5617672;R-HSA-9613644;R-HSA-5621002;R-HSA-9622386;R-HSA-9616243;R-HSA-8853734;R-HSA-560491;R-HSA-9616241;R-HSA-5617462;R-HSA-8850786;R-HSA-381283;R-HSA-8865505;R-HSA-5617471;R-HSA-8855915;R-HSA-9634430;R-HSA-9634429;R-HSA-8853737;R-HSA-5617445;R-HSA-373748;R-HSA-8854899;R-HSA-9014652;R-HSA-8854897;R-HSA-8853745;R-HSA-5617452;R-HSA-5617454;R-HSA-8854908;R-HSA-6810139;R-HSA-8853755;R-HSA-8853753;R-HSA-8854905" R-HSA-2187338,"Visual phototransduction",4,169,0.01151775369726709,0.9527074113971786,0.9527074113971786,2,92,0.007097670112636938,9606,Homo sapiens,"AKR1C1;RDH10;AKR1C3","","R-HSA-74872;R-HSA-2855252" R-HSA-8979227,"Triglyceride metabolism",1,66,0.004498057656920875,0.9529508535198263,0.9529508535198263,1,24,0.001851566116340071,9606,Homo sapiens,"FABP5","","R-HSA-5334794" R-HSA-5668541,"TNFR2 non-canonical NF-kB pathway",2,104,0.007087848429087439,0.9530167875512652,0.9530167875512652,12,43,0.0033173892917759606,9606,Homo sapiens,"CD40;BIRC3","","R-HSA-5668454;R-HSA-5668534;R-HSA-5676598;R-HSA-5676596;R-HSA-5676597;R-HSA-5676595;R-HSA-5668481;R-HSA-5676593;R-HSA-5668417;R-HSA-5668414;R-HSA-5668543;R-HSA-199404" R-HSA-9033241,"Peroxisomal protein import",1,67,0.0045662100456621,0.9550848553862321,0.9550848553862321,3,26,0.0020058632927017436,9606,Homo sapiens,"EPHX2","","R-HSA-9033233;R-HSA-9033235;R-HSA-9033236" R-HSA-421270,"Cell-cell junction organization",1,67,0.0045662100456621,0.9550848553862321,0.9550848553862321,1,21,0.001620120351797562,9606,Homo sapiens,"CLDN23","","R-HSA-420019" R-HSA-5687128,"MAPK6/MAPK4 signaling",2,106,0.00722415320656989,0.9565054405301454,0.9565054405301454,3,40,0.0030859435272334516,9606,Homo sapiens,"CDK1;ETV4","","R-HSA-5692755;R-HSA-5687099;R-HSA-5687097" R-HSA-352230,"Amino acid transport across the plasma membrane",1,68,0.004634362434403326,0.9571222018844003,0.9571222018844003,1,36,0.0027773491745101066,9606,Homo sapiens,"SLC7A5","","R-HSA-352232" R-HSA-190236,"Signaling by FGFR",2,107,0.007292305595311115,0.9581554602308581,0.9581554602308581,86,142,0.010955099521678753,9606,Homo sapiens,"FGF5;FGF7","","R-HSA-5654614;R-HSA-5654615;R-HSA-5654612;R-HSA-5654608;R-HSA-5654224;R-HSA-5654622;R-HSA-5654623;R-HSA-5654620;R-HSA-5654618;R-HSA-5654596;R-HSA-5654597;R-HSA-5654594;R-HSA-5654592;R-HSA-5654222;R-HSA-5654607;R-HSA-5654605;R-HSA-5654730;R-HSA-5654603;R-HSA-5654600;R-HSA-5654729;R-HSA-5654646;R-HSA-5654647;R-HSA-5654643;R-HSA-5654640;R-HSA-5654641;R-HSA-5654399;R-HSA-5654397;R-HSA-5654392;R-HSA-190258;R-HSA-5654631;R-HSA-5654628;R-HSA-190256;R-HSA-8941628;R-HSA-190260;R-HSA-190388;R-HSA-5654625;R-HSA-190261;R-HSA-5654511;R-HSA-8941618;R-HSA-5654637;R-HSA-5654634;R-HSA-5654633;R-HSA-8941623;R-HSA-5654679;R-HSA-5654167;R-HSA-5654677;R-HSA-5654165;R-HSA-5654672;R-HSA-5654416;R-HSA-5654673;R-HSA-190408;R-HSA-190413;R-HSA-5656070;R-HSA-5654406;R-HSA-5654407;R-HSA-5654404;R-HSA-5654148;R-HSA-5654149;R-HSA-5654402;R-HSA-5654147;R-HSA-5656064;R-HSA-5654159;R-HSA-5654157;R-HSA-5654413;R-HSA-5654408;R-HSA-5654409;R-HSA-190429;R-HSA-5654582;R-HSA-5654709;R-HSA-5654578;R-HSA-5654705;R-HSA-5654591;R-HSA-5654586;R-HSA-5654587;R-HSA-5654584;R-HSA-5654692;R-HSA-5654565;R-HSA-5654562;R-HSA-5654690;R-HSA-5654560;R-HSA-5654575;R-HSA-5654701;R-HSA-5654573;R-HSA-5654571;R-HSA-5654697;R-HSA-5654569" R-HSA-381340,"Transcriptional regulation of white adipocyte differentiation",2,108,0.007360457984052341,0.9597454442908887,0.9597454442908887,5,18,0.0013886745872550533,9606,Homo sapiens,"CEBPA","","R-HSA-1183058;R-HSA-560491;R-HSA-381283;R-HSA-1183003;R-HSA-1183032" R-HSA-449147,"Signaling by Interleukins",21,639,0.04354937640564302,0.9610821805718281,0.9610821805718281,40,490,0.03780280820860978,9606,Homo sapiens,"DUSP4;IL11;HIST1H3J;MMP1;IL1R2;SOD2;LMNB1;TG;POC1A;BIRC5;HIST1H3B;IL6R;HIST1H3C;IL18R1;MAP2K6","","R-HSA-6785895;R-HSA-727819;R-HSA-1067667;R-HSA-9617941;R-HSA-1112727;R-HSA-9008577;R-HSA-8848335;R-HSA-6789615;R-HSA-1112602;R-HSA-8865613;R-HSA-8848395;R-HSA-1112604;R-HSA-1067676;R-HSA-8950681;R-HSA-1112514;R-HSA-1067651;R-HSA-1112708;R-HSA-203797;R-HSA-450333;R-HSA-1067659;R-HSA-6790022;R-HSA-1112690;R-HSA-1112755;R-HSA-449829;R-HSA-9008684;R-HSA-1112565;R-HSA-1067640;R-HSA-8865711;R-HSA-450346;R-HSA-1112510;R-HSA-1112703;R-HSA-8937656;R-HSA-6790036;R-HSA-446130;R-HSA-8848370;R-HSA-1067688;R-HSA-9009072;R-HSA-445757;R-HSA-450296;R-HSA-449976" R-HSA-9020702,"Interleukin-1 signaling",2,109,0.007428610372793566,0.9612774396237197,0.9612774396237197,3,46,0.003548835056318469,9606,Homo sapiens,"IL1R2;MAP2K6","","R-HSA-727819;R-HSA-446130;R-HSA-445757" R-HSA-5658442,"Regulation of RAS by GAPs",1,71,0.004838819600627002,0.962697047239793,0.962697047239793,2,5,3.8574294090418145E-4,9606,Homo sapiens,"RASA4B;RASA4","","R-HSA-5658231;R-HSA-5658435" R-HSA-5684996,"MAPK1/MAPK3 signaling",10,352,0.023989640836911335,0.963678651313972,0.963678651313972,8,82,0.006326184230828576,9606,Homo sapiens,"BTC;DUSP4;FGF5;FGF7;RASA4B;RASA4;POC1A;CDK1;CDC25C;IL6R","","R-HSA-109857;R-HSA-5658231;R-HSA-5672965;R-HSA-109858;R-HSA-5658435;R-HSA-5675376;R-HSA-112342;R-HSA-5675373" R-HSA-1483257,"Phospholipid metabolism",9,325,0.02214952634089825,0.9643847785541324,0.9643847785541324,20,218,0.01681839222342231,9606,Homo sapiens,"TMEM86A;MCM8;RARRES3;CFI;PLD1;NES;MFSD2A","","R-HSA-1482646;R-HSA-1483063;R-HSA-8865637;R-HSA-8874435;R-HSA-1482546;R-HSA-1482547;R-HSA-1602398;R-HSA-1602417;R-HSA-1483142;R-HSA-1602377;R-HSA-1482533;R-HSA-1482691;R-HSA-1602446;R-HSA-1482689;R-HSA-1483182;R-HSA-1602368;R-HSA-1482636;R-HSA-8858298;R-HSA-1482667;R-HSA-1602374" R-HSA-389661,"Glyoxylate metabolism and glycine degradation",1,72,0.0049069719893682275,0.9643895583232144,0.9643895583232144,1,23,0.0017744175281592346,9606,Homo sapiens,"HOGA1","","R-HSA-6784423" R-HSA-111885,"Opioid Signalling",2,112,0.007633067539017243,0.9655450395281261,0.9655450395281261,5,59,0.004551766702669341,9606,Homo sapiens,"PLCB4;KPNA2","","R-HSA-112037;R-HSA-9619127;R-HSA-111879;R-HSA-112282;R-HSA-111870" R-HSA-8878166,"Transcriptional regulation by RUNX2",3,147,0.01001840114496013,0.9659882436199447,0.9659882436199447,3,84,0.006480481407190248,9606,Homo sapiens,"BMP2;CCNB1;CDK1","","R-HSA-9007707;R-HSA-9008832;R-HSA-9009282" R-HSA-6802952,"Signaling by BRAF and RAF fusions",1,73,0.004975124378109453,0.9660053848375653,0.9660053848375653,5,5,3.8574294090418145E-4,9606,Homo sapiens,"BCL2L11","","R-HSA-6802935;R-HSA-6802934;R-HSA-6802933;R-HSA-6802932;R-HSA-6802927" R-HSA-1793185,"Chondroitin sulfate/dermatan sulfate metabolism",1,73,0.004975124378109453,0.9660053848375653,0.9660053848375653,1,28,0.002160160469063416,9606,Homo sapiens,"XYLT1","","R-HSA-1878002" R-HSA-1474228,"Degradation of the extracellular matrix",3,148,0.010086553533701356,0.9671550454776549,0.9671550454776549,35,105,0.00810060175898781,9606,Homo sapiens,"ADAMTS4;MMP1","","R-HSA-1474197;R-HSA-4086205;R-HSA-1604763;R-HSA-1564179;R-HSA-3791295;R-HSA-1604690;R-HSA-2534248;R-HSA-1564120;R-HSA-1454791;R-HSA-1566981;R-HSA-3788075;R-HSA-3791149;R-HSA-1566979;R-HSA-1592270;R-HSA-8940561;R-HSA-375135;R-HSA-1564169;R-HSA-1604359;R-HSA-1592316;R-HSA-1566962;R-HSA-1454781;R-HSA-1592436;R-HSA-1454843;R-HSA-1592310;R-HSA-1454822;R-HSA-1604712;R-HSA-1592297;R-HSA-1602473;R-HSA-1592362;R-HSA-1474213;R-HSA-1454757;R-HSA-2533970;R-HSA-1564143;R-HSA-1564142;R-HSA-2168923" R-HSA-74259,"Purine catabolism",1,74,0.005043276766850678,0.9675479963208141,0.9675479963208141,2,28,0.002160160469063416,9606,Homo sapiens,"PNP","","R-HSA-74242;R-HSA-74249" R-HSA-1474244,"Extracellular matrix organization",9,329,0.02242213589586315,0.9677271012508447,0.9677271012508447,47,318,0.02453325104150594,9606,Homo sapiens,"ADAMTS4;BMP2;ADAMTS3;MMP1;SERPINE1;LOXL3;EMILIN2;LTBP1","","R-HSA-2328033;R-HSA-1474197;R-HSA-4086205;R-HSA-1604763;R-HSA-1564179;R-HSA-3791295;R-HSA-1604690;R-HSA-2396399;R-HSA-2396079;R-HSA-2534248;R-HSA-1564120;R-HSA-1454791;R-HSA-1566981;R-HSA-3788075;R-HSA-2328048;R-HSA-3791149;R-HSA-1566979;R-HSA-1592270;R-HSA-8940561;R-HSA-375135;R-HSA-1564169;R-HSA-1604359;R-HSA-2161282;R-HSA-2002428;R-HSA-2022141;R-HSA-1592316;R-HSA-2395328;R-HSA-1566962;R-HSA-2395340;R-HSA-1454781;R-HSA-1592436;R-HSA-1454843;R-HSA-1592310;R-HSA-1454822;R-HSA-1604712;R-HSA-1592297;R-HSA-1602473;R-HSA-2213200;R-HSA-1592362;R-HSA-1474213;R-HSA-1454757;R-HSA-2533970;R-HSA-1564143;R-HSA-1564142;R-HSA-2168923;R-HSA-2002466;R-HSA-2129375" R-HSA-1650814,"Collagen biosynthesis and modifying enzymes",1,76,0.005179581544333129,0.970426675642838,0.970426675642838,1,51,0.003934577997222651,9606,Homo sapiens,"ADAMTS3","","R-HSA-2002428" R-HSA-1227986,"Signaling by ERBB2",1,78,0.00531588632181558,0.9730503425761312,0.9730503425761312,18,46,0.003548835056318469,9606,Homo sapiens,"BTC","","R-HSA-1963581;R-HSA-1250195;R-HSA-8848005;R-HSA-1963582;R-HSA-6785636;R-HSA-1250486;R-HSA-1963578;R-HSA-1306969;R-HSA-1250463;R-HSA-1306972;R-HSA-1306979;R-HSA-1963563;R-HSA-6785648;R-HSA-1963589;R-HSA-1250346;R-HSA-8863804;R-HSA-8847995;R-HSA-1963586" R-HSA-1799339,"SRP-dependent cotranslational protein targeting to membrane",2,119,0.00811013426020582,0.9738157619931707,0.9738157619931707,5,5,3.8574294090418145E-4,9606,Homo sapiens,"RPL39L;SPC25","","R-HSA-1799326;R-HSA-1799330;R-HSA-1799329;R-HSA-1799335;R-HSA-1799332" R-HSA-9679191,"Potential therapeutics for SARS",2,119,0.00811013426020582,0.9738157619931707,0.9738157619931707,2,33,0.0025459034099675976,9606,Homo sapiens,"TUBB;IL6R","","R-HSA-9685830;R-HSA-9681294" R-HSA-3000178,"ECM proteoglycans",1,79,0.005384038710556805,0.9742736764833178,0.9742736764833178,1,23,0.0017744175281592346,9606,Homo sapiens,"SERPINE1","","R-HSA-2396079" R-HSA-913531,"Interferon Signaling",11,396,0.02698834594152525,0.9752736889645535,0.9752736889645535,7,66,0.005091806819935195,9606,Homo sapiens,"ISG20;MT2A;GBP2;IFIT1;KPNA2;IFIT2","","R-HSA-1678841;R-HSA-1015702;R-HSA-1176059;R-HSA-1031716;R-HSA-1015699;R-HSA-1031713;R-HSA-1169406" R-HSA-351202,"Metabolism of polyamines",1,80,0.00545219109929803,0.9754415574040524,0.9754415574040524,2,17,0.001311525999074217,9606,Homo sapiens,"GBP2","","R-HSA-351207;R-HSA-351208" R-HSA-4086398,"Ca2+ pathway",1,81,0.005520343488039256,0.9765564954444641,0.9765564954444641,2,27,0.00208301188088258,9606,Homo sapiens,"TCF7","","R-HSA-8944362;R-HSA-4411365" R-HSA-397014,"Muscle contraction",6,254,0.017310706740271246,0.9768949414596813,0.9768949414596813,8,41,0.003163092115414288,9606,Homo sapiens,"GUCY1A2;ACTC1;KCND3;TNNC2;NEB;CLIC2","","R-HSA-390597;R-HSA-390598;R-HSA-390593;R-HSA-390595;R-HSA-5577234;R-HSA-2855020;R-HSA-392143;R-HSA-392152" R-HSA-1236394,"Signaling by ERBB4",1,82,0.005588495876780481,0.9776208872499772,0.9776208872499772,12,52,0.004011726585403487,9606,Homo sapiens,"BTC","","R-HSA-1250370;R-HSA-1250353;R-HSA-1250357;R-HSA-1250315;R-HSA-1977958;R-HSA-1977959;R-HSA-1251992;R-HSA-1250383;R-HSA-1236398;R-HSA-1250380;R-HSA-1250348;R-HSA-1250220" R-HSA-5653656,"Vesicle-mediated transport",27,824,0.05615756832276971,0.9778234439234658,0.9778234439234658,37,251,0.01936429563338991,9606,Homo sapiens,"KIF23;RAB27B;STON2;KIF22;KIF11;TUBB4B;RAB33A;KIF15;BTC;TUBA1C;CENPE;TUBB6;TUBA1B;KIF18A;KIF18B;RACGAP1;KIFC1;TUBB3;KIF4A;CDK2;AGTR1;MAN1C1;KIF2C;KIF20B","","R-HSA-8868230;R-HSA-8849350;R-HSA-6811426;R-HSA-6809006;R-HSA-8868236;R-HSA-6809003;R-HSA-8849353;R-HSA-8854612;R-HSA-8847635;R-HSA-2316347;R-HSA-8866269;R-HSA-8871194;R-HSA-8871193;R-HSA-190877;R-HSA-8868071;R-HSA-8863463;R-HSA-8866279;R-HSA-8863727;R-HSA-8867756;R-HSA-8863723;R-HSA-8868651;R-HSA-8866283;R-HSA-8867754;R-HSA-8863721;R-HSA-8868072;R-HSA-8868648;R-HSA-8868661;R-HSA-8868660;R-HSA-8868659;R-HSA-8868658;R-HSA-6811423;R-HSA-8869438;R-HSA-190520;R-HSA-8877308;R-HSA-191737;R-HSA-8847544;R-HSA-8875320" R-HSA-917937,"Iron uptake and transport",1,83,0.005656648265521706,0.9786370211266477,0.9786370211266477,4,34,0.002623051998148434,9606,Homo sapiens,"SLC40A1","","R-HSA-917933;R-HSA-904830;R-HSA-442368;R-HSA-917891" R-HSA-8939902,"Regulation of RUNX2 expression and activity",1,83,0.005656648265521706,0.9786370211266477,0.9786370211266477,1,32,0.002468754821786761,9606,Homo sapiens,"BMP2","","R-HSA-9007707" R-HSA-5683057,"MAPK family signaling cascades",11,403,0.02746541266271383,0.979084157176466,0.979084157176466,11,122,0.009412127758062027,9606,Homo sapiens,"BTC;DUSP4;FGF5;FGF7;RASA4B;RASA4;POC1A;CDK1;CDC25C;ETV4;IL6R","","R-HSA-109857;R-HSA-5658231;R-HSA-5672965;R-HSA-109858;R-HSA-5692755;R-HSA-5658435;R-HSA-5675376;R-HSA-112342;R-HSA-5675373;R-HSA-5687099;R-HSA-5687097" R-HSA-446652,"Interleukin-1 family signaling",3,163,0.011108839364819737,0.9806973023101058,0.9806973023101058,9,79,0.006094738466286067,9606,Homo sapiens,"IL1R2;IL18R1;MAP2K6","","R-HSA-727819;R-HSA-446130;R-HSA-9008684;R-HSA-8848370;R-HSA-9008577;R-HSA-8848335;R-HSA-9009072;R-HSA-445757;R-HSA-8848395" R-HSA-2151201,"Transcriptional activation of mitochondrial biogenesis",1,87,0.005929257820486608,0.9822612193632734,0.9822612193632734,1,32,0.002468754821786761,9606,Homo sapiens,"SOD2","","R-HSA-5688289" R-HSA-2029485,"Role of phospholipids in phagocytosis",2,129,0.008791658147618075,0.9823892916699535,0.9823892916699535,1,12,9.257830581700355E-4,9606,Homo sapiens,"PLD1","","R-HSA-2029471" R-HSA-6806834,"Signaling by MET",1,88,0.005997410209227834,0.9830669265737545,0.9830669265737545,4,49,0.003780280820860978,9606,Homo sapiens,"LIG1","","R-HSA-8875431;R-HSA-8875443;R-HSA-8875490;R-HSA-8875374" R-HSA-375280,"Amine ligand-binding receptors",1,88,0.005997410209227834,0.9830669265737545,0.9830669265737545,1,20,0.0015429717636167258,9606,Homo sapiens,"HTR2B","","R-HSA-390930" R-HSA-1638091,"Heparan sulfate/heparin (HS-GAG) metabolism",1,88,0.005997410209227834,0.9830669265737545,0.9830669265737545,1,33,0.0025459034099675976,9606,Homo sapiens,"XYLT1","","R-HSA-1878002" R-HSA-5579029,"Metabolic disorders of biological oxidation enzymes",1,88,0.005997410209227834,0.9830669265737545,0.9830669265737545,1,39,0.003008794939052615,9606,Homo sapiens,"TBXAS1","","R-HSA-5603275" R-HSA-76002,"Platelet activation, signaling and aggregation",7,296,0.02017310706740271,0.9834950290625734,0.9834950290625734,3,115,0.008872087640796174,9606,Homo sapiens,"CLEC3B;TG;SERPINE1;SERPING1;EMILIN2;RAB27B;SEPP1","","R-HSA-481010;R-HSA-481009;R-HSA-481007" R-HSA-446219,"Synthesis of substrates in N-glycan biosythesis",2,131,0.008927962925100525,0.9837419147561032,0.9837419147561032,2,49,0.003780280820860978,9606,Homo sapiens,"GMPPB;RENBP","","R-HSA-6803761;R-HSA-446221" R-HSA-9018677,"Biosynthesis of DHA-derived SPMs",1,89,0.006065562597969059,0.9838360895456345,0.9838360895456345,1,58,0.004474618114488505,9606,Homo sapiens,"EPHX2","","R-HSA-9024993" R-HSA-1483249,"Inositol phosphate metabolism",1,90,0.006133714986710284,0.9845703634687849,0.9845703634687849,1,71,0.005477549760839377,9606,Homo sapiens,"PLCB4","","R-HSA-1855177" R-HSA-195253,"Degradation of beta-catenin by the destruction complex",1,91,0.00620186737545151,0.9852713286708029,0.9852713286708029,4,23,0.0017744175281592346,9606,Homo sapiens,"TCF7","","R-HSA-8944349;R-HSA-8944352;R-HSA-4641231;R-HSA-5229348" R-HSA-9013694,"Signaling by NOTCH4",1,92,0.006270019764192735,0.9859404939981596,0.9859404939981596,1,20,0.0015429717636167258,9606,Homo sapiens,"TACC3","","R-HSA-9604675" R-HSA-6794362,"Protein-protein interactions at synapses",1,93,0.00633817215293396,0.9865793000448426,0.9865793000448426,3,33,0.0025459034099675976,9606,Homo sapiens,"PTPRF","","R-HSA-6798258;R-HSA-8855648;R-HSA-388824" R-HSA-8951664,"Neddylation",5,241,0.016424725686635316,0.9867656398722492,0.9867656398722492,12,31,0.002391606233605925,9606,Homo sapiens,"LRR1;CCNF;BIRC5;KBTBD8;DTL","","R-HSA-8956040;R-HSA-8956200;R-HSA-8955289;R-HSA-8955241;R-HSA-8952618;R-HSA-8956026;R-HSA-8952620;R-HSA-8956045;R-HSA-8955245;R-HSA-8952638;R-HSA-8952639;R-HSA-8955285" R-HSA-5419276,"Mitochondrial translation termination",1,94,0.006406324541675185,0.9871891222353872,0.9871891222353872,5,5,3.8574294090418145E-4,9606,Homo sapiens,"BRIP1","","R-HSA-5419264;R-HSA-5419281;R-HSA-5419271;R-HSA-5419273;R-HSA-5419277" R-HSA-5389840,"Mitochondrial translation elongation",1,94,0.006406324541675185,0.9871891222353872,0.9871891222353872,5,8,6.171887054466903E-4,9606,Homo sapiens,"BRIP1","","R-HSA-5389842;R-HSA-5389857;R-HSA-5389848;R-HSA-5419279;R-HSA-5419261" R-HSA-446728,"Cell junction organization",1,94,0.006406324541675185,0.9871891222353872,0.9871891222353872,1,37,0.0028544977626909426,9606,Homo sapiens,"CLDN23","","R-HSA-420019" R-HSA-375276,"Peptide ligand-binding receptors",4,211,0.014380154024398555,0.9880291020382941,0.9880291020382941,5,76,0.005863292701743558,9606,Homo sapiens,"PNP;TACR2;AGTR1;ACKR3","","R-HSA-9615249;R-HSA-374214;R-HSA-383363;R-HSA-374173;R-HSA-388863" R-HSA-977606,"Regulation of Complement cascade",2,139,0.009473182035030328,0.9882115282486513,0.9882115282486513,13,42,0.003240240703595124,9606,Homo sapiens,"CFI;SERPING1","","R-HSA-977359;R-HSA-977615;R-HSA-976810;R-HSA-8852481;R-HSA-976743;R-HSA-981637;R-HSA-3266557;R-HSA-977602;R-HSA-8852266;R-HSA-976801;R-HSA-9021306;R-HSA-981658;R-HSA-977371" R-HSA-5368286,"Mitochondrial translation initiation",1,96,0.006542629319157636,0.9883270084298911,0.9883270084298911,1,4,3.0859435272334514E-4,9606,Homo sapiens,"BRIP1","","R-HSA-5389839" R-HSA-168928,"DDX58/IFIH1-mediated induction of interferon-alpha/beta",1,96,0.006542629319157636,0.9883270084298911,0.9883270084298911,1,46,0.003548835056318469,9606,Homo sapiens,"TNFAIP3","","R-HSA-937337" R-HSA-156902,"Peptide chain elongation",1,97,0.0066107817078988615,0.9888575232732659,0.9888575232732659,4,5,3.8574294090418145E-4,9606,Homo sapiens,"RPL39L","","R-HSA-156915;R-HSA-156912;R-HSA-156923;R-HSA-156907" R-HSA-174824,"Plasma lipoprotein assembly, remodeling, and clearance",1,98,0.0066789340966400875,0.9893639611869024,0.9893639611869024,2,84,0.006480481407190248,9606,Homo sapiens,"LSR","","R-HSA-8933258;R-HSA-8933292" R-HSA-373080,"Class B/2 (Secretin family receptors)",1,99,0.006747086485381313,0.9898474133395604,0.9898474133395604,2,20,0.0015429717636167258,9606,Homo sapiens,"ADGRE5","","R-HSA-444773;R-HSA-879674" R-HSA-983168,"Antigen processing: Ubiquitination & Proteasome degradation",7,315,0.021468002453485995,0.9904756164293005,0.9904756164293005,5,9,6.943372936275266E-4,9606,Homo sapiens,"CDC20;UBE2S;UBE2C;LRR1;CCNF;KBTBD8;TRAIP","","R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152" R-HSA-975956,"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)",1,101,0.006883391262863764,0.9907494803584463,0.9907494803584463,1,1,7.714858818083629E-5,9606,Homo sapiens,"RPL39L","","R-HSA-927789" R-HSA-5368287,"Mitochondrial translation",1,102,0.006951543651604989,0.9911700394779845,0.9911700394779845,11,17,0.001311525999074217,9606,Homo sapiens,"BRIP1","","R-HSA-5389842;R-HSA-5419264;R-HSA-5389857;R-HSA-5419281;R-HSA-5419271;R-HSA-5389848;R-HSA-5419273;R-HSA-5419279;R-HSA-5389839;R-HSA-5419261;R-HSA-5419277" R-HSA-156842,"Eukaryotic Translation Elongation",1,102,0.006951543651604989,0.9911700394779845,0.9911700394779845,4,9,6.943372936275266E-4,9606,Homo sapiens,"RPL39L","","R-HSA-156915;R-HSA-156912;R-HSA-156923;R-HSA-156907" R-HSA-15869,"Metabolism of nucleotides",5,254,0.017310706740271246,0.9912908945787118,0.9912908945787118,10,135,0.0104150594044129,9606,Homo sapiens,"RRM2;PNP;TK1;TYMS;AK8","","R-HSA-112033;R-HSA-73632;R-HSA-74242;R-HSA-112034;R-HSA-73605;R-HSA-111751;R-HSA-110137;R-HSA-74249;R-HSA-110138;R-HSA-111742" R-HSA-2980736,"Peptide hormone metabolism",2,147,0.01001840114496013,0.9914753109111425,0.9914753109111425,4,63,0.004860361055392687,9606,Homo sapiens,"CPB1;SPC25","","R-HSA-422051;R-HSA-400496;R-HSA-2028294;R-HSA-400459" R-HSA-112315,"Transmission across Chemical Synapses",8,352,0.023989640836911335,0.9920399226213649,0.9920399226213649,5,162,0.01249807128529548,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;TUBB4B;KPNA2","","R-HSA-9610627;R-HSA-9619542;R-HSA-9619127;R-HSA-9610408;R-HSA-112282" R-HSA-156580,"Phase II - Conjugation of compounds",5,258,0.01758331629523615,0.9923569468337532,0.9923569468337532,9,72,0.005554698349020213,9606,Homo sapiens,"SULT1A1;GSTM3;CHAC2","","R-HSA-158849;R-HSA-176646;R-HSA-176054;R-HSA-158468;R-HSA-176474;R-HSA-176585;R-HSA-158860;R-HSA-176669;R-HSA-6785928" R-HSA-72764,"Eukaryotic Translation Termination",1,106,0.00722415320656989,0.9926698068167147,0.9926698068167147,3,5,3.8574294090418145E-4,9606,Homo sapiens,"RPL39L","","R-HSA-141671;R-HSA-141691;R-HSA-141673" R-HSA-72689,"Formation of a pool of free 40S subunits",1,106,0.00722415320656989,0.9926698068167147,0.9926698068167147,1,2,1.5429717636167257E-4,9606,Homo sapiens,"RPL39L","","R-HSA-72673" R-HSA-1296071,"Potassium Channels",1,107,0.007292305595311115,0.9930031733139268,0.9930031733139268,1,19,0.0014658231754358896,9606,Homo sapiens,"KCND3","","R-HSA-1296127" R-HSA-9675108,"Nervous system development",17,620,0.04225448101955973,0.993447031663603,0.993447031663603,33,323,0.024918993982410122,9606,Homo sapiens,"RPL39L;CD72;TUBB4B;CDC25C;TUBA1C;GAP43;TUBB6;TUBA1B;TUBB3;KIF4A;MPZ;ADGRG6;MBP;PLXNC1","","R-HSA-8854981;R-HSA-8855747;R-HSA-8853762;R-HSA-8855617;R-HSA-445071;R-HSA-8853774;R-HSA-8855564;R-HSA-9614787;R-HSA-445077;R-HSA-8855508;R-HSA-9614273;R-HSA-9614790;R-HSA-8933328;R-HSA-9014610;R-HSA-9613644;R-HSA-8853734;R-HSA-8853793;R-HSA-9614773;R-HSA-8853792;R-HSA-434989;R-HSA-8855915;R-HSA-9614271;R-HSA-8853737;R-HSA-8853800;R-HSA-373748;R-HSA-8854899;R-HSA-9014652;R-HSA-8854897;R-HSA-8853745;R-HSA-8854908;R-HSA-8853755;R-HSA-8853753;R-HSA-8854905" R-HSA-446203,"Asparagine N-linked glycosylation",10,421,0.028692155660055885,0.9937270845028618,0.9937270845028618,7,144,0.011109396698040426,9606,Homo sapiens,"GMPPB;TUBA1C;TUBA1B;TUBB6;TUBB3;MAN1C1;TUBB4B;RENBP","","R-HSA-964830;R-HSA-6803761;R-HSA-964825;R-HSA-6809006;R-HSA-446221;R-HSA-6809003;R-HSA-964737" R-HSA-166658,"Complement cascade",2,156,0.01063177264363116,0.9940975679985425,0.9940975679985425,13,71,0.005477549760839377,9606,Homo sapiens,"CFI;SERPING1","","R-HSA-977359;R-HSA-977615;R-HSA-976810;R-HSA-8852481;R-HSA-976743;R-HSA-981637;R-HSA-3266557;R-HSA-977602;R-HSA-8852266;R-HSA-976801;R-HSA-9021306;R-HSA-981658;R-HSA-977371" R-HSA-428157,"Sphingolipid metabolism",2,157,0.010699925032372385,0.9943348101687729,0.9943348101687729,6,62,0.00478321246721185,9606,Homo sapiens,"CERS4;PPM1L","","R-HSA-429732;R-HSA-429730;R-HSA-429699;R-HSA-429683;R-HSA-429694;R-HSA-428185" R-HSA-162582,"Signal Transduction",130,3396,0.2314455121652014,0.9945199179688318,0.9945199179688318,355,2386,0.18407653139947538,9606,Homo sapiens,"ERCC6L;ZWILCH;SERPINE1;CASC5;BUB1B;FGF5;CDC20;FGF7;TUBB6;PNP;TUBB3;HIST1H2AE;HIST1H2AD;KNTC1;KPNA2;IL6R;LIG1;HIST1H2AK;CDC25C;SGO1;BTC;SGO2;DEPDC1B;RRAGD;AGTR1;HIST1H2BF;HIST1H2BE;HIST1H2BG;HIST1H2BB;SCG2;HIST1H2BD;HIST1H2BC;HIST1H3J;TCF7;CDCA8;ARHGAP18;IQGAP3;SKA1;PORCN;ARHGAP20;DSN1;BCL2L11;RACGAP1;RDH10;HIST1H3B;ECT2;HIST1H4L;PLK1;ARHGAP28;NEB;H2BFS;NDC80;ZWINT;FOSL1;KIF18A;BMP2;HIST1H4B;DIAPH3;REEP4;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;EZH2;ARHGAP11A;RTP4;KIF14;HTR2B;TNFAIP3;GLI1;TUBA1C;TUBA1B;ADGRE5;NUF2;RSPO2;SPDL1;DLGAP5;DUSP4;RASA4B;H2AFZ;MMP1;H2AFX;TACR2;HIST2H2BB;F3;ETV4;PLCB4;RBL1;INCENP;RASA4;ARHGEF3;BIRC5;KIF2C;DOCK2;BIRC3;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;CENPA;AURKB;HIST2H4A;E2F1;POC1A;S1PR3;BUB3;BUB1;CENPU;AKR1C1;AKR1C3;TUBB4B;CENPE;CENPF;FABP5;PRC1;CENPI;CENPK;TACC3;CENPL;ACKR3;CENPM;CENPN;CENPO;CENPQ;SPC24;SPC25;MAD2L1","","R-HSA-5654614;R-HSA-5654615;R-HSA-114688;R-HSA-5654612;R-HSA-8848005;R-HSA-6785636;R-HSA-3322422;R-HSA-5654608;R-HSA-5654622;R-HSA-5654623;R-HSA-3322427;R-HSA-5654620;R-HSA-3322424;R-HSA-5654618;R-HSA-5654596;R-HSA-5654597;R-HSA-5654594;R-HSA-203797;R-HSA-5654592;R-HSA-6785648;R-HSA-1250315;R-HSA-5654607;R-HSA-5654605;R-HSA-5654603;R-HSA-5654600;R-HSA-1963581;R-HSA-5654646;R-HSA-5654647;R-HSA-5658231;R-HSA-1250353;R-HSA-1963582;R-HSA-9018538;R-HSA-5654643;R-HSA-9619127;R-HSA-1250357;R-HSA-5654640;R-HSA-1963578;R-HSA-5654641;R-HSA-9018542;R-HSA-5693055;R-HSA-5626469;R-HSA-5654631;R-HSA-5654628;R-HSA-380979;R-HSA-1963563;R-HSA-5654625;R-HSA-879674;R-HSA-1250346;R-HSA-5654637;R-HSA-5654634;R-HSA-1250348;R-HSA-5654633;R-HSA-8943817;R-HSA-9624272;R-HSA-9625813;R-HSA-8951490;R-HSA-9604831;R-HSA-5625883;R-HSA-9604829;R-HSA-5656070;R-HSA-1250370;R-HSA-201810;R-HSA-9009371;R-HSA-5672965;R-HSA-8944349;R-HSA-5656064;R-HSA-1963589;R-HSA-5625870;R-HSA-1250383;R-HSA-201821;R-HSA-1963586;R-HSA-1250380;R-HSA-8867047;R-HSA-5654582;R-HSA-5615668;R-HSA-5634100;R-HSA-419428;R-HSA-8944362;R-HSA-8867044;R-HSA-447074;R-HSA-9011949;R-HSA-5654578;R-HSA-8867041;R-HSA-9011950;R-HSA-8944352;R-HSA-5654591;R-HSA-9009378;R-HSA-9011941;R-HSA-5654586;R-HSA-5654587;R-HSA-5654584;R-HSA-9604834;R-HSA-5654565;R-HSA-5671970;R-HSA-5654562;R-HSA-5654560;R-HSA-9011966;R-HSA-1977958;R-HSA-74872;R-HSA-1977959;R-HSA-9011952;R-HSA-5654575;R-HSA-5654573;R-HSA-1912416;R-HSA-5654571;R-HSA-5654569;R-HSA-5357776;R-HSA-109699;R-HSA-5357780;R-HSA-5654224;R-HSA-3364026;R-HSA-1251992;R-HSA-1250463;R-HSA-5654222;R-HSA-8848414;R-HSA-112282;R-HSA-4395231;R-HSA-5654730;R-HSA-3364014;R-HSA-5654729;R-HSA-5610741;R-HSA-9621042;R-HSA-5610742;R-HSA-5610737;R-HSA-1250486;R-HSA-380073;R-HSA-379048;R-HSA-140978;R-HSA-2316434;R-HSA-8848436;R-HSA-8941628;R-HSA-5610723;R-HSA-5610733;R-HSA-9621035;R-HSA-8941618;R-HSA-8863804;R-HSA-182969;R-HSA-5633256;R-HSA-8941623;R-HSA-5654679;R-HSA-5654167;R-HSA-5654677;R-HSA-5654165;R-HSA-3299569;R-HSA-5654672;R-HSA-5654673;R-HSA-182986;R-HSA-182990;R-HSA-182994;R-HSA-9604675;R-HSA-5654148;R-HSA-182993;R-HSA-5654149;R-HSA-5654147;R-HSA-112342;R-HSA-183002;R-HSA-5654159;R-HSA-5654157;R-HSA-5626507;R-HSA-201443;R-HSA-5626549;R-HSA-212706;R-HSA-5693108;R-HSA-5654709;R-HSA-212710;R-HSA-5654705;R-HSA-212713;R-HSA-205039;R-HSA-5357757;R-HSA-201453;R-HSA-201457;R-HSA-5654692;R-HSA-5654690;R-HSA-3364042;R-HSA-2106586;R-HSA-388863;R-HSA-5654701;R-HSA-8847995;R-HSA-183036;R-HSA-5654697;R-HSA-111870;R-HSA-177922;R-HSA-201475;R-HSA-177923;R-HSA-5357904;R-HSA-9615249;R-HSA-8952716;R-HSA-177926;R-HSA-177927;R-HSA-5692755;R-HSA-177924;R-HSA-111879;R-HSA-5362518;R-HSA-177925;R-HSA-201476;R-HSA-5666129;R-HSA-177930;R-HSA-183051;R-HSA-75016;R-HSA-177934;R-HSA-5422942;R-HSA-177935;R-HSA-183055;R-HSA-177933;R-HSA-177938;R-HSA-183058;R-HSA-205075;R-HSA-177939;R-HSA-177936;R-HSA-177937;R-HSA-5671749;R-HSA-177942;R-HSA-177943;R-HSA-5658435;R-HSA-390930;R-HSA-177941;R-HSA-3238694;R-HSA-9625482;R-HSA-183067;R-HSA-177944;R-HSA-177945;R-HSA-9625487;R-HSA-8952726;R-HSA-5665608;R-HSA-109857;R-HSA-9009065;R-HSA-8875431;R-HSA-183072;R-HSA-109858;R-HSA-5622129;R-HSA-3451153;R-HSA-5672304;R-HSA-5666160;R-HSA-5675376;R-HSA-5654399;R-HSA-5672828;R-HSA-5654397;R-HSA-5672824;R-HSA-183084;R-HSA-5654392;R-HSA-5666169;R-HSA-190258;R-HSA-165680;R-HSA-190256;R-HSA-381750;R-HSA-183089;R-HSA-8875443;R-HSA-190260;R-HSA-190261;R-HSA-5357928;R-HSA-5675373;R-HSA-165692;R-HSA-3451147;R-HSA-5635861;R-HSA-5666070;R-HSA-5635860;R-HSA-9031624;R-HSA-5357845;R-HSA-5635859;R-HSA-5635868;R-HSA-1306969;R-HSA-5635864;R-HSA-1306972;R-HSA-5635845;R-HSA-5617412;R-HSA-5610758;R-HSA-5635846;R-HSA-165718;R-HSA-5635841;R-HSA-1484099;R-HSA-5617408;R-HSA-5635843;R-HSA-5635842;R-HSA-419166;R-HSA-5635853;R-HSA-5610767;R-HSA-5610766;R-HSA-5610760;R-HSA-5635848;R-HSA-5635850;R-HSA-8944104;R-HSA-194913;R-HSA-444773;R-HSA-8875490;R-HSA-377186;R-HSA-194922;R-HSA-398188;R-HSA-5229348;R-HSA-9012196;R-HSA-5687099;R-HSA-5671737;R-HSA-5687097;R-HSA-1306979;R-HSA-5357860;R-HSA-9017855;R-HSA-9012209;R-HSA-9012208;R-HSA-2855252;R-HSA-5653974;R-HSA-1250195;R-HSA-749448;R-HSA-9011981;R-HSA-749454;R-HSA-383363;R-HSA-5653968;R-HSA-9011983;R-HSA-749452;R-HSA-4641231;R-HSA-9011975;R-HSA-5625797;R-HSA-5625796;R-HSA-5653957;R-HSA-4411351;R-HSA-4641246;R-HSA-374173;R-HSA-9011985;R-HSA-9011984;R-HSA-749456;R-HSA-112037;R-HSA-4411365;R-HSA-9012000;R-HSA-5625849;R-HSA-5625848;R-HSA-4411372;R-HSA-2186643;R-HSA-201648;R-HSA-190388;R-HSA-5654511;R-HSA-2127257;R-HSA-1236398;R-HSA-1250220;R-HSA-8944457;R-HSA-374214;R-HSA-5654416;R-HSA-190408;R-HSA-8944454;R-HSA-190413;R-HSA-5654406;R-HSA-5654407;R-HSA-5654404;R-HSA-5654402;R-HSA-5654413;R-HSA-5672843;R-HSA-5654408;R-HSA-5654409;R-HSA-190429;R-HSA-5672329;R-HSA-3361751;R-HSA-8875374;R-HSA-9625465;R-HSA-5625784;R-HSA-4641206;R-HSA-4641205;R-HSA-201712;R-HSA-5625774" R-HSA-2408557,"Selenocysteine synthesis",1,113,0.007701219927758468,0.9947084105531732,0.9947084105531732,2,7,5.40040117265854E-4,9606,Homo sapiens,"RPL39L","","R-HSA-2408529;R-HSA-5333615" R-HSA-446193,"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein",2,159,0.010836229809854835,0.9947816095801502,0.9947816095801502,2,63,0.004860361055392687,9606,Homo sapiens,"GMPPB;RENBP","","R-HSA-6803761;R-HSA-446221" R-HSA-192823,"Viral mRNA Translation",1,114,0.007769372316499694,0.994949177354929,0.994949177354929,2,2,1.5429717636167257E-4,9606,Homo sapiens,"RPL39L","","R-HSA-192704;R-HSA-192841" R-HSA-611105,"Respiratory electron transport",1,115,0.007837524705240918,0.9951790047114747,0.9951790047114747,6,19,0.0014658231754358896,9606,Homo sapiens,"E2F1","","R-HSA-6799191;R-HSA-163217;R-HSA-6799202;R-HSA-6799197;R-HSA-6799196;R-HSA-6799179" R-HSA-9633012,"Response of EIF2AK4 (GCN2) to amino acid deficiency",1,115,0.007837524705240918,0.9951790047114747,0.9951790047114747,4,16,0.0012343774108933806,9606,Homo sapiens,"RPL39L","","R-HSA-9633008;R-HSA-9633742;R-HSA-9634669;R-HSA-9633005" R-HSA-5673001,"RAF/MAP kinase cascade",7,345,0.023512574115722756,0.9961492254584802,0.9961492254584802,5,75,0.005786144113562722,9606,Homo sapiens,"BTC;DUSP4;FGF5;FGF7;RASA4B;RASA4;POC1A;CDC25C","","R-HSA-5658231;R-HSA-5672965;R-HSA-5658435;R-HSA-5675376;R-HSA-5675373" R-HSA-72706,"GTP hydrolysis and joining of the 60S ribosomal subunit",1,120,0.008178286648947045,0.9961806557577318,0.9961806557577318,2,3,2.3144576454250888E-4,9606,Homo sapiens,"RPL39L","","R-HSA-72672;R-HSA-72671" R-HSA-156827,"L13a-mediated translational silencing of Ceruloplasmin expression",1,120,0.008178286648947045,0.9961806557577318,0.9961806557577318,1,3,2.3144576454250888E-4,9606,Homo sapiens,"RPL39L","","R-HSA-156826" R-HSA-2672351,"Stimuli-sensing channels",1,120,0.008178286648947045,0.9961806557577318,0.9961806557577318,1,26,0.0020058632927017436,9606,Homo sapiens,"CLIC2","","R-HSA-2855020" R-HSA-983712,"Ion channel transport",3,207,0.014107544469433653,0.9962193540500391,0.9962193540500391,3,41,0.003163092115414288,9606,Homo sapiens,"ATP8B4;CLIC2","","R-HSA-2855020;R-HSA-947591;R-HSA-939763" R-HSA-418346,"Platelet homeostasis",1,123,0.008382743815170722,0.996678889088438,0.996678889088438,2,30,0.0023144576454250886,9606,Homo sapiens,"GUCY1A2","","R-HSA-392143;R-HSA-392152" R-HSA-6807070,"PTEN Regulation",2,171,0.01165405847474954,0.9968211243983679,0.9968211243983679,4,56,0.004320320938126832,9606,Homo sapiens,"RRAGD;EZH2","","R-HSA-8944104;R-HSA-8944457;R-HSA-8943817;R-HSA-8944454" R-HSA-927802,"Nonsense-Mediated Decay (NMD)",1,124,0.008450896203911947,0.9968301007680577,0.9968301007680577,5,6,4.6289152908501776E-4,9606,Homo sapiens,"RPL39L","","R-HSA-927836;R-HSA-927789;R-HSA-927832;R-HSA-927813;R-HSA-927889" R-HSA-975957,"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)",1,124,0.008450896203911947,0.9968301007680577,0.9968301007680577,4,5,3.8574294090418145E-4,9606,Homo sapiens,"RPL39L","","R-HSA-927836;R-HSA-927832;R-HSA-927813;R-HSA-927889" R-HSA-5628897,"TP53 Regulates Metabolic Genes",1,125,0.008519048592653173,0.9969744374026537,0.9969744374026537,1,34,0.002623051998148434,9606,Homo sapiens,"RRAGD","","R-HSA-380979" R-HSA-5576891,"Cardiac conduction",2,173,0.01179036325223199,0.9970744531353554,0.9970744531353554,2,26,0.0020058632927017436,9606,Homo sapiens,"KCND3;CLIC2","","R-HSA-5577234;R-HSA-2855020" R-HSA-877300,"Interferon gamma signaling",4,252,0.017174401962788795,0.9971556308218283,0.9971556308218283,2,15,0.0011572288227125443,9606,Homo sapiens,"MT2A;GBP2","","R-HSA-1031716;R-HSA-1031713" R-HSA-1989781,"PPARA activates gene expression",2,174,0.011858515640973216,0.9971935683069079,0.9971935683069079,1,41,0.003163092115414288,9606,Homo sapiens,"GLIPR1","","R-HSA-1989772" R-HSA-1592230,"Mitochondrial biogenesis",1,127,0.008655353370135623,0.9972437199552558,0.9972437199552558,1,36,0.0027773491745101066,9606,Homo sapiens,"SOD2","","R-HSA-5688289" R-HSA-400206,"Regulation of lipid metabolism by PPARalpha",2,176,0.011994820418455667,0.9974176732158244,0.9974176732158244,1,44,0.0033945378799567967,9606,Homo sapiens,"GLIPR1","","R-HSA-1989772" R-HSA-162587,"HIV Life Cycle",2,177,0.012062972807196893,0.9975230300680139,0.9975230300680139,1,115,0.008872087640796174,9606,Homo sapiens,"FEN1;LIG1","","R-HSA-182876" R-HSA-72613,"Eukaryotic Translation Initiation",1,130,0.0088598105363593,0.9976034378263398,0.9976034378263398,4,21,0.001620120351797562,9606,Homo sapiens,"RPL39L","","R-HSA-72673;R-HSA-72672;R-HSA-156826;R-HSA-72671" R-HSA-72737,"Cap-dependent Translation Initiation",1,130,0.0088598105363593,0.9976034378263398,0.9976034378263398,3,18,0.0013886745872550533,9606,Homo sapiens,"RPL39L","","R-HSA-72673;R-HSA-72672;R-HSA-72671" R-HSA-202733,"Cell surface interactions at the vascular wall",4,257,0.01751516390649492,0.9976252980016166,0.9976252980016166,4,64,0.004937509643573522,9606,Homo sapiens,"SLC7A5;THBD;MMP1;PSG1","","R-HSA-141040;R-HSA-375135;R-HSA-8870732;R-HSA-375131" R-HSA-9607240,"FLT3 Signaling",7,362,0.024671164724323586,0.9977367472014846,0.9977367472014846,6,97,0.00748341305354112,9606,Homo sapiens,"BTC;DUSP4;FGF5;FGF7;RASA4B;RASA4;POC1A;CDC25C","","R-HSA-5658231;R-HSA-109699;R-HSA-5672965;R-HSA-5658435;R-HSA-5675376;R-HSA-5675373" R-HSA-2408522,"Selenoamino acid metabolism",2,181,0.012335582362161793,0.997903784432274,0.997903784432274,3,33,0.0025459034099675976,9606,Homo sapiens,"RPL39L;INMT","","R-HSA-2408529;R-HSA-2408554;R-HSA-5333615" R-HSA-1500931,"Cell-Cell communication",1,133,0.009064267702582975,0.9979162695901402,0.9979162695901402,1,60,0.004628915290850177,9606,Homo sapiens,"CLDN23","","R-HSA-420019" R-HSA-1630316,"Glycosaminoglycan metabolism",2,182,0.01240373475090302,0.9979895904097872,0.9979895904097872,4,88,0.006789075759913593,9606,Homo sapiens,"XYLT1;HMMR","","R-HSA-2160915;R-HSA-2160884;R-HSA-2160892;R-HSA-1878002" R-HSA-6809371,"Formation of the cornified envelope",1,138,0.009405029646289103,0.9983496791466937,0.9983496791466937,1,27,0.00208301188088258,9606,Homo sapiens,"RBL1","","R-HSA-8850786" R-HSA-8956319,"Nucleobase catabolism",1,139,0.009473182035030328,0.9984248947522052,0.9984248947522052,2,58,0.004474618114488505,9606,Homo sapiens,"PNP","","R-HSA-74242;R-HSA-74249" R-HSA-6791226,"Major pathway of rRNA processing in the nucleolus and cytosol",2,189,0.012880801472091597,0.9985006672071928,0.9985006672071928,1,7,5.40040117265854E-4,9606,Homo sapiens,"ISG20;RPL39L","","R-HSA-6791218" R-HSA-2029480,"Fcgamma receptor (FCGR) dependent phagocytosis",2,193,0.013153411027056498,0.9987327639650941,0.9987327639650941,1,42,0.003240240703595124,9606,Homo sapiens,"PLD1","","R-HSA-2029471" R-HSA-1280218,"Adaptive Immune System",28,999,0.06808423635248416,0.9988116529796085,0.9988116529796085,10,261,0.02013578151519827,9606,Homo sapiens,"CD40;LRR1;CCNF;KIF11;KIF15;CDC20;TUBA1C;TUBB6;TUBA1B;RACGAP1;TUBB3;CD14;UBE2C;IL1R2;KIF23;KIF22;TUBB4B;TRAIP;CENPE;KIF18A;CLEC2B;UBE2S;KIF4A;KIF2C;KBTBD8","","R-HSA-8863895;R-HSA-2213248;R-HSA-983147;R-HSA-8856157;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-5685608;R-HSA-199404;R-HSA-983152" R-HSA-392499,"Metabolism of proteins",81,2356,0.160567027874327,0.9989407496563772,0.9989407496563772,122,892,0.06881654065730597,9606,Homo sapiens,"TOP2A;GALNT15;GALNT18;LRR1;CCNF;TNFAIP3;BRCA1;GMPPB;CDC20;ADAMTS4;TUBA1C;TUBB6;TUBA1B;ADAMTS3;TUBB3;HIST1H2AE;HIST1H2AD;LMCD1;IGFBP5;H2AFZ;HIST1H2AH;MMP1;HIST1H2AK;H2AFX;HIST2H2BB;MITF;RENBP;HIST2H2BF;RAB33A;CDC25A;CCNA2;CCNE2;RTN4RL1;INCENP;HIST1H2BF;BIRC5;HIST1H2BE;FAM20A;HIST1H2BG;HIST1H2BB;SCG2;DTL;HIST1H2BD;HIST1H2BC;BIRC3;HIST1H2BN;HIST1H2BM;BLM;CPB1;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;CDCA8;LTBP1;AURKB;AURKA;HIST2H4A;BRIP1;RAB20;MAN1C1;GCNT3;CLSPN;HIST1H3B;RPL39L;UBE2C;HIST1H4L;RAB27B;H2BFS;TUBB4B;HIST1H4B;RAET1G;UBE2S;UBE2T;CDK2;CDK1;HIST1H4H;HIST1H4C;KBTBD8;HIST1H4D;HIST1H4E;SPC25;WRAP53","","R-HSA-8956040;R-HSA-4641350;R-HSA-688136;R-HSA-6781797;R-HSA-8956045;R-HSA-8869506;R-HSA-913675;R-HSA-446221;R-HSA-5696600;R-HSA-8955289;R-HSA-8943003;R-HSA-4568914;R-HSA-8943007;R-HSA-2028294;R-HSA-8852127;R-HSA-8955285;R-HSA-8852130;R-HSA-8852129;R-HSA-4570485;R-HSA-5389842;R-HSA-389956;R-HSA-5419281;R-HSA-5173005;R-HSA-390470;R-HSA-5691411;R-HSA-977224;R-HSA-389955;R-HSA-389954;R-HSA-8943040;R-HSA-389964;R-HSA-8943041;R-HSA-5389848;R-HSA-389961;R-HSA-400459;R-HSA-389963;R-HSA-914012;R-HSA-389972;R-HSA-5419264;R-HSA-389974;R-HSA-389969;R-HSA-5419271;R-HSA-8955869;R-HSA-6803761;R-HSA-389970;R-HSA-389980;R-HSA-5419273;R-HSA-5419279;R-HSA-5389839;R-HSA-2997616;R-HSA-389976;R-HSA-5419277;R-HSA-389978;R-HSA-381537;R-HSA-141671;R-HSA-8952289;R-HSA-8865774;R-HSA-4655404;R-HSA-141673;R-HSA-381545;R-HSA-914018;R-HSA-5389857;R-HSA-400496;R-HSA-4641342;R-HSA-141691;R-HSA-5690157;R-HSA-1799326;R-HSA-5173192;R-HSA-5690845;R-HSA-964737;R-HSA-3232162;R-HSA-5696960;R-HSA-156826;R-HSA-8942099;R-HSA-8942101;R-HSA-5690827;R-HSA-8956200;R-HSA-5690870;R-HSA-8952618;R-HSA-5228525;R-HSA-5691381;R-HSA-8952620;R-HSA-422051;R-HSA-5697009;R-HSA-8867370;R-HSA-5419261;R-HSA-8955706;R-HSA-5690080;R-HSA-8952638;R-HSA-8952639;R-HSA-1799330;R-HSA-1799329;R-HSA-4655355;R-HSA-1799335;R-HSA-8866105;R-HSA-5690856;R-HSA-1799332;R-HSA-8870469;R-HSA-5696914;R-HSA-8870466;R-HSA-4570496;R-HSA-8955712;R-HSA-6809006;R-HSA-8940100;R-HSA-6809003;R-HSA-964830;R-HSA-964825;R-HSA-72671;R-HSA-2997709;R-HSA-72673;R-HSA-8955241;R-HSA-72672;R-HSA-8955245;R-HSA-5683888;R-HSA-5696958;R-HSA-156907;R-HSA-8940388;R-HSA-5690790;R-HSA-156915;R-HSA-8956026;R-HSA-156912;R-HSA-156923;R-HSA-381435" R-HSA-1257604,"PIP3 activates AKT signaling",5,316,0.02153615484222722,0.9989407744431087,0.9989407744431087,5,86,0.006634778583551921,9606,Homo sapiens,"BTC;FGF5;FGF7;RRAGD;EZH2","","R-HSA-8944104;R-HSA-2316434;R-HSA-8944457;R-HSA-8943817;R-HSA-8944454" R-HSA-168255,"Influenza Infection",2,200,0.013630477748245075,0.9990567582435195,0.9990567582435195,4,59,0.004551766702669341,9606,Homo sapiens,"RPL39L;KPNA2","","R-HSA-192704;R-HSA-1176059;R-HSA-192841;R-HSA-6791035" R-HSA-163200,"Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.",1,150,0.010222858311183807,0.999057306228407,0.999057306228407,6,31,0.002391606233605925,9606,Homo sapiens,"E2F1","","R-HSA-6799191;R-HSA-163217;R-HSA-6799202;R-HSA-6799197;R-HSA-6799196;R-HSA-6799179" R-HSA-162909,"Host Interactions of HIV factors",1,150,0.010222858311183807,0.999057306228407,0.999057306228407,1,54,0.00416602376176516,9606,Homo sapiens,"DOCK2","","R-HSA-200952" R-HSA-416476,"G alpha (q) signalling events",4,283,0.01928712601376678,0.9990853067036949,0.9990853067036949,5,35,0.00270020058632927,9606,Homo sapiens,"PLCB4;TACR2;HTR2B;AGTR1","","R-HSA-114688;R-HSA-749448;R-HSA-749452;R-HSA-398188;R-HSA-379048" R-HSA-3781865,"Diseases of glycosylation",2,202,0.013766782525727527,0.9991332553088461,0.9991332553088461,1,77,0.005940441289924395,9606,Homo sapiens,"ADAMTS4;ADAMTS3","","R-HSA-6785565" R-HSA-422475,"Axon guidance",13,584,0.03980099502487562,0.9991434432060233,0.9991434432060233,27,297,0.022913130689708378,9606,Homo sapiens,"RPL39L;TUBA1C;TUBA1B;GAP43;TUBB6;CD72;TUBB3;KIF4A;PLXNC1;TUBB4B;CDC25C","","R-HSA-8854981;R-HSA-8855747;R-HSA-8853762;R-HSA-8855617;R-HSA-445071;R-HSA-8853774;R-HSA-8855564;R-HSA-445077;R-HSA-8855508;R-HSA-8933328;R-HSA-9014610;R-HSA-8853734;R-HSA-8853793;R-HSA-8853792;R-HSA-434989;R-HSA-8855915;R-HSA-8853737;R-HSA-8853800;R-HSA-373748;R-HSA-8854899;R-HSA-9014652;R-HSA-8854897;R-HSA-8853745;R-HSA-8854908;R-HSA-8853755;R-HSA-8853753;R-HSA-8854905" R-HSA-1280215,"Cytokine Signaling in Immune system",39,1312,0.0894159340284877,0.9991929615011018,0.9991929615011018,65,735,0.05670421231291467,9606,Homo sapiens,"CD40;HIST1H3J;IFIT1;LMNB1;IFIT2;FGF5;MT2A;FGF7;POC1A;GBP2;KPNA2;HIST1H3B;IL6R;HIST1H3C;MAP2K6;DUSP4;IL11;RASA4B;MMP1;IL1R2;SOD2;CDC25C;BTC;ISG20;TG;RASA4;BIRC5;IL18R1;BIRC3","","R-HSA-6785895;R-HSA-727819;R-HSA-109699;R-HSA-1067667;R-HSA-9617941;R-HSA-1112727;R-HSA-6789615;R-HSA-1112602;R-HSA-8848395;R-HSA-1112604;R-HSA-1067676;R-HSA-8950681;R-HSA-1067651;R-HSA-1112708;R-HSA-5658435;R-HSA-203797;R-HSA-5668417;R-HSA-1015702;R-HSA-450333;R-HSA-1067659;R-HSA-1015699;R-HSA-5658231;R-HSA-1112755;R-HSA-449829;R-HSA-9008684;R-HSA-5675376;R-HSA-8865711;R-HSA-1031716;R-HSA-450346;R-HSA-1112510;R-HSA-1031713;R-HSA-8937656;R-HSA-5668454;R-HSA-446130;R-HSA-1067688;R-HSA-9009072;R-HSA-5675373;R-HSA-445757;R-HSA-449976;R-HSA-9008577;R-HSA-8848335;R-HSA-8865613;R-HSA-1112514;R-HSA-5672965;R-HSA-5668481;R-HSA-5668534;R-HSA-1678841;R-HSA-5676598;R-HSA-6790022;R-HSA-1112690;R-HSA-5676596;R-HSA-5676597;R-HSA-1112565;R-HSA-5676595;R-HSA-5676593;R-HSA-5668414;R-HSA-1067640;R-HSA-5668543;R-HSA-1176059;R-HSA-199404;R-HSA-1169406;R-HSA-1112703;R-HSA-6790036;R-HSA-8848370;R-HSA-450296" R-HSA-9006925,"Intracellular signaling by second messengers",6,363,0.02473931711306481,0.9992858757785108,0.9992858757785108,7,114,0.008794939052615337,9606,Homo sapiens,"BTC;FGF5;FGF7;RRAGD;KPNA2;EZH2","","R-HSA-8944104;R-HSA-2316434;R-HSA-8944457;R-HSA-8943817;R-HSA-9619127;R-HSA-112282;R-HSA-8944454" R-HSA-8868773,"rRNA processing in the nucleus and cytosol",2,207,0.014107544469433653,0.999298728056826,0.999298728056826,1,15,0.0011572288227125443,9606,Homo sapiens,"ISG20;RPL39L","","R-HSA-6791218" R-HSA-112316,"Neuronal System",10,498,0.03393988959313024,0.9993141643985964,0.9993141643985964,9,215,0.016586946458879804,9606,Homo sapiens,"TUBA1C;TUBA1B;TUBB6;TUBB3;KCND3;TUBB4B;KPNA2;PTPRF","","R-HSA-9610627;R-HSA-9619542;R-HSA-9619127;R-HSA-6798258;R-HSA-8855648;R-HSA-9610408;R-HSA-112282;R-HSA-1296127;R-HSA-388824" R-HSA-9018678,"Biosynthesis of specialized proresolving mediators (SPMs)",1,159,0.010836229809854835,0.999380786499283,0.999380786499283,1,124,0.0095664249344237,9606,Homo sapiens,"EPHX2","","R-HSA-9024993" R-HSA-1236974,"ER-Phagosome pathway",1,165,0.011245144142302188,0.9995321671526228,0.9995321671526228,1,10,7.714858818083629E-4,9606,Homo sapiens,"CD14","","R-HSA-8863895" R-HSA-425366,"Transport of bile salts and organic acids, metal ions and amine compounds",1,165,0.011245144142302188,0.9995321671526228,0.9995321671526228,2,67,0.005168955408116032,9606,Homo sapiens,"SLC40A1","","R-HSA-904830;R-HSA-442368" R-HSA-425393,"Transport of inorganic cations/anions and amino acids/oligopeptides",1,165,0.011245144142302188,0.9995321671526228,0.9995321671526228,1,75,0.005786144113562722,9606,Homo sapiens,"SLC7A5","","R-HSA-352232" R-HSA-3858494,"Beta-catenin independent WNT signaling",1,166,0.011313296531043413,0.999553528030229,0.999553528030229,2,51,0.003934577997222651,9606,Homo sapiens,"TCF7","","R-HSA-8944362;R-HSA-4411365" R-HSA-162906,"HIV Infection",3,262,0.01785592585020105,0.9995583521323382,0.9995583521323382,2,158,0.012189476932572134,9606,Homo sapiens,"FEN1;LIG1;DOCK2","","R-HSA-200952;R-HSA-182876" R-HSA-9609507,"Protein localization",1,170,0.011585906086008315,0.9996296655156023,0.9996296655156023,3,53,0.004088875173584324,9606,Homo sapiens,"EPHX2","","R-HSA-9033233;R-HSA-9033235;R-HSA-9033236" R-HSA-168273,"Influenza Viral RNA Transcription and Replication",1,176,0.011994820418455667,0.9997202615999239,0.9997202615999239,2,14,0.001080080234531708,9606,Homo sapiens,"RPL39L","","R-HSA-192704;R-HSA-192841" R-HSA-983169,"Class I MHC mediated antigen processing & presentation",8,465,0.0316908607646698,0.9997603472146178,0.9997603472146178,6,48,0.003703132232680142,9606,Homo sapiens,"CDC20;UBE2S;UBE2C;LRR1;CCNF;CD14;KBTBD8;TRAIP","","R-HSA-8863895;R-HSA-983147;R-HSA-983157;R-HSA-983156;R-HSA-983140;R-HSA-983152" R-HSA-9679506,"SARS-CoV Infections",2,234,0.01594765896544674,0.9997786516978844,0.9997786516978844,2,143,0.01103224810985959,9606,Homo sapiens,"TUBB;IL6R","","R-HSA-9685830;R-HSA-9681294" R-HSA-8957322,"Metabolism of steroids",4,322,0.02194506917467457,0.9997905190691773,0.9997905190691773,6,235,0.01812991822249653,9606,Homo sapiens,"AKR1C1;AKR1C3;AKR1C2","","R-HSA-192160;R-HSA-193841;R-HSA-192036;R-HSA-193781;R-HSA-193800;R-HSA-193758" R-HSA-9010553,"Regulation of expression of SLITs and ROBOs",1,183,0.012471887139644245,0.9997983773787089,0.9997983773787089,2,20,0.0015429717636167258,9606,Homo sapiens,"RPL39L","","R-HSA-9014652;R-HSA-9014610" R-HSA-5619102,"SLC transporter disorders",1,185,0.012608191917126695,0.999816390815915,0.999816390815915,3,65,0.005014658231754359,9606,Homo sapiens,"SLC40A1","","R-HSA-5655733;R-HSA-5655760;R-HSA-5621402" R-HSA-211897,"Cytochrome P450 - arranged by substrate type",1,185,0.012608191917126695,0.999816390815915,0.999816390815915,1,61,0.004706063879031014,9606,Homo sapiens,"TBXAS1","","R-HSA-76500" R-HSA-1236975,"Antigen processing-Cross presentation",1,187,0.012744496694609145,0.9998327970507792,0.9998327970507792,1,23,0.0017744175281592346,9606,Homo sapiens,"CD14","","R-HSA-8863895" R-HSA-72312,"rRNA processing",2,245,0.01669733524160022,0.9998621854685688,0.9998621854685688,1,21,0.001620120351797562,9606,Homo sapiens,"ISG20;RPL39L","","R-HSA-6791218" R-HSA-8978868,"Fatty acid metabolism",6,429,0.029237374769985686,0.9999304738187859,0.9999304738187859,11,217,0.016741243635241473,9606,Homo sapiens,"DEPDC1B;EPHX2;AKR1C1;ELOVL3;TBXAS1;AKR1C3;PTGES","","R-HSA-2046094;R-HSA-76500;R-HSA-548814;R-HSA-2046088;R-HSA-548815;R-HSA-548800;R-HSA-2161961;R-HSA-2161660;R-HSA-2161549;R-HSA-2161613;R-HSA-2161614" R-HSA-6805567,"Keratinization",1,226,0.015402439855516935,0.9999731195795782,0.9999731195795782,1,34,0.002623051998148434,9606,Homo sapiens,"RBL1","","R-HSA-8850786" R-HSA-418594,"G alpha (i) signalling events",9,568,0.03871055680501602,0.9999757185644137,0.9999757185644137,10,165,0.012729517049837987,9606,Homo sapiens,"PLCB4;PNP;AKR1C1;RDH10;AKR1C3;ACKR3;S1PR3;KPNA2","","R-HSA-112037;R-HSA-749454;R-HSA-9619127;R-HSA-111879;R-HSA-74872;R-HSA-749456;R-HSA-112282;R-HSA-380073;R-HSA-2855252;R-HSA-111870" R-HSA-373076,"Class A/1 (Rhodopsin-like receptors)",6,462,0.03148640359844612,0.999979290764337,0.999979290764337,7,152,0.011726585403487116,9606,Homo sapiens,"PNP;TACR2;HTR2B;AGTR1;ACKR3;S1PR3","","R-HSA-419428;R-HSA-9615249;R-HSA-374214;R-HSA-383363;R-HSA-390930;R-HSA-374173;R-HSA-388863" R-HSA-1428517,"The citric acid (TCA) cycle and respiratory electron transport",1,233,0.015879506576705515,0.9999806477743363,0.9999806477743363,6,67,0.005168955408116032,9606,Homo sapiens,"E2F1","","R-HSA-6799191;R-HSA-163217;R-HSA-6799202;R-HSA-6799197;R-HSA-6799196;R-HSA-6799179" R-HSA-72766,"Translation",3,339,0.023103659783275405,0.9999809523926129,0.9999809523926129,27,99,0.007637710229902793,9606,Homo sapiens,"RPL39L;BRIP1;SPC25","","R-HSA-5389842;R-HSA-5419281;R-HSA-1799326;R-HSA-5389848;R-HSA-5419264;R-HSA-5419271;R-HSA-156826;R-HSA-5419273;R-HSA-5419279;R-HSA-5389839;R-HSA-72671;R-HSA-5419277;R-HSA-72673;R-HSA-72672;R-HSA-141671;R-HSA-156907;R-HSA-141673;R-HSA-5419261;R-HSA-156915;R-HSA-156912;R-HSA-5389857;R-HSA-156923;R-HSA-1799330;R-HSA-141691;R-HSA-1799329;R-HSA-1799335;R-HSA-1799332" R-HSA-376176,"Signaling by ROBO receptors",1,235,0.016015811354187965,0.9999823824579456,0.9999823824579456,2,60,0.004628915290850177,9606,Homo sapiens,"RPL39L","","R-HSA-9014652;R-HSA-9014610" R-HSA-211945,"Phase I - Functionalization of compounds",2,298,0.020309411844885165,0.9999863231520402,0.9999863231520402,2,98,0.007560561641721956,9606,Homo sapiens,"TBXAS1;ACSS1","","R-HSA-449911;R-HSA-76500" R-HSA-198933,"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell",2,316,0.02153615484222722,0.9999938143578568,0.9999938143578568,2,43,0.0033173892917759606,9606,Homo sapiens,"CD40;CLEC2B","","R-HSA-5685608;R-HSA-199404" R-HSA-5663202,"Diseases of signal transduction by growth factor receptors and second messengers",6,499,0.03400804198187146,0.999994836991142,0.999994836991142,62,396,0.03055084091961117,9606,Homo sapiens,"BTC;FGF5;PORCN;FGF7;BCL2L11;POC1A","","R-HSA-2023455;R-HSA-2023451;R-HSA-6802927;R-HSA-5655262;R-HSA-5655263;R-HSA-5654748;R-HSA-6802935;R-HSA-6802934;R-HSA-6802933;R-HSA-6802932;R-HSA-5655233;R-HSA-5655247;R-HSA-5655244;R-HSA-5655245;R-HSA-5655243;R-HSA-5655240;R-HSA-5655241;R-HSA-5655285;R-HSA-9664567;R-HSA-9664950;R-HSA-5655295;R-HSA-5655290;R-HSA-2400009;R-HSA-5655289;R-HSA-9665699;R-HSA-5655270;R-HSA-5655268;R-HSA-9665697;R-HSA-5655269;R-HSA-2012074;R-HSA-5655266;R-HSA-9665701;R-HSA-9665700;R-HSA-2012073;R-HSA-5655278;R-HSA-9665705;R-HSA-5655277;R-HSA-9665709;R-HSA-5340560;R-HSA-9664976;R-HSA-9652816;R-HSA-9664983;R-HSA-5655315;R-HSA-5655326;R-HSA-9664991;R-HSA-5655323;R-HSA-5655320;R-HSA-2033488;R-HSA-2033486;R-HSA-5655301;R-HSA-2033474;R-HSA-2033472;R-HSA-9664588;R-HSA-1839100;R-HSA-1839098;R-HSA-1225978;R-HSA-1839094;R-HSA-2077424;R-HSA-2077421;R-HSA-2077420;R-HSA-5655343;R-HSA-5655339" R-HSA-5663205,"Infectious disease",33,1374,0.09364138213044368,0.9999957197310748,0.9999957197310748,17,637,0.049143650671192717,9606,Homo sapiens,"HIST1H2BN;HIST1H2BM;FEN1;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;TUBA1C;TUBB6;TUBA1B;TUBB3;HIST1H2AE;HIST1H2AD;KPNA2;HIST1H3B;IL6R;MAP2K6;RPL39L;LIG1;HIST1H4L;HIST1H2AH;TUBB;HIST1H2AK;HIST2H2BB;TUBB4B;HIST2H2BF;HIST1H4B;HIST1H2BF;HIST1H4H;HIST1H2BE;HIST1H2BG;HIST1H4C;DOCK2;HIST1H2BB;HIST1H4D;HIST1H4E;HIST1H2BD;HIST1H2BC;EZH2","","R-HSA-5211405;R-HSA-192704;R-HSA-9621073;R-HSA-9614810;R-HSA-9614811;R-HSA-9623096;R-HSA-1176059;R-HSA-192841;R-HSA-9614367;R-HSA-9614816;R-HCY-9625991;R-HSA-9614343;R-HSA-9685830;R-HSA-200952;R-HSA-6791035;R-HSA-9681294;R-HSA-182876" R-HSA-211859,"Biological oxidations",7,545,0.03714305186396783,0.9999960052465983,0.9999960052465983,11,188,0.014503934577997223,9606,Homo sapiens,"SULT1A1;GSTM3;TBXAS1;CHAC2;ACSS1","","R-HSA-449911;R-HSA-158849;R-HSA-176646;R-HSA-176054;R-HSA-76500;R-HSA-158468;R-HSA-176474;R-HSA-176585;R-HSA-158860;R-HSA-176669;R-HSA-6785928" R-HSA-9006934,"Signaling by Receptor Tyrosine Kinases",9,622,0.04239078579704219,0.999996281867537,0.999996281867537,165,701,0.05408116031476624,9606,Homo sapiens,"BTC;DUSP4;FGF5;FOSL1;FGF7;LIG1;POC1A;F3","","R-HSA-5654614;R-HSA-177922;R-HSA-5654615;R-HSA-177923;R-HSA-5654612;R-HSA-8848005;R-HSA-6785636;R-HSA-177926;R-HSA-177927;R-HSA-5654608;R-HSA-177924;R-HSA-177925;R-HSA-5654622;R-HSA-177930;R-HSA-183051;R-HSA-5654623;R-HSA-5654620;R-HSA-5654618;R-HSA-177934;R-HSA-177935;R-HSA-183055;R-HSA-177933;R-HSA-177938;R-HSA-183058;R-HSA-177939;R-HSA-177936;R-HSA-5654596;R-HSA-177937;R-HSA-5654597;R-HSA-177942;R-HSA-5654594;R-HSA-177943;R-HSA-203797;R-HSA-5654592;R-HSA-177941;R-HSA-6785648;R-HSA-1250315;R-HSA-5654607;R-HSA-183067;R-HSA-177944;R-HSA-5654605;R-HSA-177945;R-HSA-5654603;R-HSA-5654600;R-HSA-1963581;R-HSA-5654646;R-HSA-8875431;R-HSA-5654647;R-HSA-1250353;R-HSA-183072;R-HSA-1963582;R-HSA-5654643;R-HSA-1250357;R-HSA-5654640;R-HSA-1963578;R-HSA-5654641;R-HSA-5654399;R-HSA-5654397;R-HSA-183084;R-HSA-5654392;R-HSA-190258;R-HSA-5654631;R-HSA-5654628;R-HSA-190256;R-HSA-183089;R-HSA-8875443;R-HSA-190260;R-HSA-1963563;R-HSA-5654625;R-HSA-190261;R-HSA-1250346;R-HSA-5654637;R-HSA-5654634;R-HSA-1250348;R-HSA-5654633;R-HSA-9031624;R-HSA-1306969;R-HSA-8951490;R-HSA-1306972;R-HSA-5656070;R-HSA-1250370;R-HSA-5656064;R-HSA-1963589;R-HSA-1250383;R-HSA-1963586;R-HSA-1250380;R-HSA-8867047;R-HSA-5654582;R-HSA-8867044;R-HSA-5654578;R-HSA-8875490;R-HSA-8867041;R-HSA-5654591;R-HSA-5654586;R-HSA-5654587;R-HSA-5654584;R-HSA-1306979;R-HSA-5654565;R-HSA-5654562;R-HSA-5654560;R-HSA-1977958;R-HSA-1977959;R-HSA-5654575;R-HSA-5654573;R-HSA-5654571;R-HSA-5654569;R-HSA-1250195;R-HSA-109699;R-HSA-5654224;R-HSA-1251992;R-HSA-1250463;R-HSA-5654222;R-HSA-5654730;R-HSA-5654729;R-HSA-9621042;R-HSA-1250486;R-HSA-8941628;R-HSA-190388;R-HSA-5654511;R-HSA-9621035;R-HSA-8941618;R-HSA-8863804;R-HSA-182969;R-HSA-1236398;R-HSA-1250220;R-HSA-8941623;R-HSA-5654679;R-HSA-5654167;R-HSA-5654677;R-HSA-5654165;R-HSA-5654672;R-HSA-5654416;R-HSA-5654673;R-HSA-182986;R-HSA-190408;R-HSA-182990;R-HSA-190413;R-HSA-5654406;R-HSA-182994;R-HSA-5654407;R-HSA-5654404;R-HSA-5654148;R-HSA-182993;R-HSA-5654149;R-HSA-5654402;R-HSA-5654147;R-HSA-183002;R-HSA-5654159;R-HSA-5654157;R-HSA-5654413;R-HSA-5654408;R-HSA-5654409;R-HSA-190429;R-HSA-212706;R-HSA-5654709;R-HSA-212710;R-HSA-5654705;R-HSA-8875374;R-HSA-212713;R-HSA-5654692;R-HSA-5654690;R-HSA-5654701;R-HSA-8847995;R-HSA-183036;R-HSA-5654697" R-HSA-196854,"Metabolism of vitamins and cofactors",3,383,0.02610236488788932,0.9999970013674391,0.9999970013674391,1,205,0.01581546057707144,9606,Homo sapiens,"AKR1C1;AKR1C3","","R-HSA-2855252" R-HSA-5619115,"Disorders of transmembrane transporters",1,280,0.019082668847543106,0.9999978778673683,0.9999978778673683,3,87,0.006711927171732758,9606,Homo sapiens,"SLC40A1","","R-HSA-5655733;R-HSA-5655760;R-HSA-5621402" R-HSA-5668914,"Diseases of metabolism",3,409,0.02787432699516118,0.9999990086736896,0.9999990086736896,2,191,0.014735380342539732,9606,Homo sapiens,"ADAMTS4;ADAMTS3;TBXAS1","","R-HSA-6785565;R-HSA-5603275" R-HSA-71291,"Metabolism of amino acids and derivatives",9,662,0.0451168813466912,0.9999991121131702,0.9999991121131702,11,285,0.021987347631538343,9606,Homo sapiens,"RPL39L;SLC7A5;ORC1;KYNU;NAGS;HOGA1;GBP2;PSPH;INMT","","R-HSA-71217;R-HSA-6784423;R-HSA-351207;R-HSA-977324;R-HSA-2408529;R-HSA-70634;R-HSA-351208;R-HSA-352232;R-HSA-2408554;R-HSA-5333615;R-HSA-70542" R-HSA-425407,"SLC-mediated transmembrane transport",3,419,0.028555850882573435,0.9999993540310439,0.9999993540310439,4,191,0.014735380342539732,9606,Homo sapiens,"SLC7A5;SLC2A12;SLC40A1","","R-HSA-429094;R-HSA-904830;R-HSA-442368;R-HSA-352232" R-HSA-168256,"Immune System",84,2869,0.19552920329857562,0.9999997302966811,0.9999997302966811,151,1634,0.1260607930874865,9606,Homo sapiens,"CD40;LRR1;CCNF;TNFAIP3;KIF11;IFIT1;LMNB1;KIF15;IFIT2;CDC20;FGF5;TUBA1C;MT2A;TUBB6;GLIPR1;TUBA1B;FGF7;PNP;ADGRE5;TUBB3;KPNA2;IL6R;DUSP4;IL11;RASA4B;MMP1;IL1R2;TUBB;KIF23;KIF22;CDC25C;ATAD3A;TRAIP;BTC;SLPI;RASA4;BIRC5;SERPING1;KIF2C;DOCK2;BIRC3;HIST1H3J;CFI;PLD1;DSN1;RACGAP1;POC1A;MBP;CD14;METTL7A;GBP2;HIST1H3B;HIST1H3C;MAP2K6;POLQ;ATP8B4;UBE2C;TUBB4B;SOD2;ISG20;CENPE;KIF18A;CLEC2B;TG;FABP5;UBE2S;KIF4A;KBTBD8;IL18R1","","R-HSA-6785895;R-HSA-727819;R-HSA-688136;R-HSA-688137;R-HSA-1112602;R-HSA-1112604;R-HSA-8863895;R-HSA-8950681;R-HSA-5362500;R-HSA-5658435;R-HSA-203797;R-HSA-936985;R-HSA-5668417;R-HSA-166168;R-HSA-450333;R-HSA-166175;R-HSA-5658231;R-HSA-2562564;R-HSA-449829;R-HSA-5675376;R-HSA-8865711;R-HSA-1031716;R-HSA-450346;R-HSA-1031713;R-HSA-8937656;R-HSA-937022;R-HSA-450358;R-HSA-5668454;R-HSA-9009072;R-HSA-5675373;R-HSA-445757;R-HSA-5685608;R-HSA-2569057;R-HSA-9008577;R-HSA-8848335;R-HSA-937029;R-HSA-6800426;R-HSA-5672965;R-HSA-6800434;R-HSA-5676598;R-HSA-1112690;R-HSA-5676596;R-HSA-5676597;R-HSA-983147;R-HSA-5676595;R-HSA-166245;R-HSA-5362486;R-HSA-5676593;R-HSA-5668414;R-HSA-1067640;R-HSA-976743;R-HSA-983140;R-HSA-937059;R-HSA-1112703;R-HSA-8848370;R-HSA-2559568;R-HSA-937337;R-HSA-937079;R-HSA-983157;R-HSA-983156;R-HSA-166271;R-HSA-937075;R-HSA-983152;R-HSA-2029471;R-HSA-109699;R-HSA-1067667;R-HSA-8852481;R-HSA-9617941;R-HSA-1112727;R-HSA-6789615;R-HSA-981637;R-HSA-8848395;R-HSA-166286;R-HSA-1067676;R-HSA-166284;R-HSA-6799350;R-HSA-2559414;R-HSA-1067651;R-HSA-166038;R-HSA-981658;R-HSA-1112708;R-HSA-1015702;R-HSA-166041;R-HSA-1067659;R-HSA-1015699;R-HSA-2213248;R-HSA-1112755;R-HSA-976810;R-HSA-9008684;R-HSA-8852266;R-HSA-1112510;R-HSA-976801;R-HSA-446130;R-HSA-2213017;R-HSA-1067688;R-HSA-8869694;R-HSA-166072;R-HSA-449976;R-HSA-166082;R-HSA-977359;R-HSA-977615;R-HSA-2201316;R-HSA-166091;R-HSA-2562541;R-HSA-8865613;R-HSA-1247960;R-HSA-2201322;R-HSA-2559468;R-HSA-3266557;R-HSA-977602;R-HSA-2559464;R-HSA-9014342;R-HSA-168915;R-HSA-1112514;R-HSA-2262775;R-HSA-977371;R-HSA-5668481;R-HSA-166362;R-HSA-166363;R-HSA-8856157;R-HSA-2262777;R-HSA-2201338;R-HSA-168921;R-HSA-5668534;R-HSA-1678841;R-HSA-6790022;R-HSA-936941;R-HSA-166119;R-HSA-1112565;R-HSA-2559439;R-HSA-5668543;R-HSA-1176059;R-HSA-2201293;R-HSA-199404;R-HSA-1169406;R-HSA-6798743;R-HSA-9021306;R-HSA-6790036;R-HSA-168950;R-HSA-6798739;R-HSA-169719;R-HSA-168951;R-HSA-936952;R-HSA-6798751;R-HSA-936951;R-HSA-6798749;R-HSA-6798748;R-HSA-6798747;R-HSA-936947;R-HSA-450296;R-HSA-6798745" R-HSA-71387,"Metabolism of carbohydrates",3,456,0.031077489265998775,0.9999998690755475,0.9999998690755475,6,243,0.01874710692794322,9606,Homo sapiens,"PHKG1;XYLT1;HMMR","","R-HSA-2160915;R-HSA-71541;R-HSA-2160884;R-HSA-2160892;R-HSA-1878002;R-HSA-453337" R-HSA-500792,"GPCR ligand binding",7,652,0.04443535745927895,0.9999999323521159,0.9999999323521159,9,179,0.013809597284369696,9606,Homo sapiens,"PNP;ADGRE5;TACR2;HTR2B;AGTR1;ACKR3;S1PR3","","R-HSA-419428;R-HSA-9615249;R-HSA-374214;R-HSA-444773;R-HSA-383363;R-HSA-390930;R-HSA-879674;R-HSA-374173;R-HSA-388863" R-HSA-381753,"Olfactory Signaling Pathway",2,432,0.029441831936209365,0.9999999657693328,0.9999999657693328,1,2,1.5429717636167257E-4,9606,Homo sapiens,"RTP4;REEP4","","R-HSA-381750" R-HSA-168249,"Innate Immune System",24,1329,0.09057452463708852,0.9999999946467564,0.9999999946467564,82,697,0.0537725659620429,9606,Homo sapiens,"DUSP4;POLQ;ATP8B4;TUBB;CFI;TNFAIP3;TUBB4B;PLD1;ATAD3A;GLIPR1;DSN1;PNP;ADGRE5;FABP5;SLPI;POC1A;SERPING1;MBP;METTL7A;CD14;DOCK2;BIRC3;MAP2K6","","R-HSA-727819;R-HSA-2029471;R-HSA-688136;R-HSA-688137;R-HSA-8852481;R-HSA-981637;R-HSA-166286;R-HSA-166284;R-HSA-6799350;R-HSA-2559414;R-HSA-166038;R-HSA-981658;R-HSA-5362500;R-HSA-203797;R-HSA-936985;R-HSA-166168;R-HSA-450333;R-HSA-166041;R-HSA-166175;R-HSA-2562564;R-HSA-976810;R-HSA-450346;R-HSA-8852266;R-HSA-976801;R-HSA-937022;R-HSA-450358;R-HSA-2213017;R-HSA-8869694;R-HSA-166072;R-HSA-166082;R-HSA-977359;R-HSA-977615;R-HSA-2201316;R-HSA-2569057;R-HSA-166091;R-HSA-2562541;R-HSA-1247960;R-HSA-2201322;R-HSA-2559468;R-HSA-937029;R-HSA-3266557;R-HSA-977602;R-HSA-6800426;R-HSA-2559464;R-HSA-9014342;R-HSA-168915;R-HSA-6800434;R-HSA-2262775;R-HSA-977371;R-HSA-166362;R-HSA-166363;R-HSA-2262777;R-HSA-2201338;R-HSA-168921;R-HSA-936941;R-HSA-166119;R-HSA-166245;R-HSA-5362486;R-HSA-2559439;R-HSA-976743;R-HSA-2201293;R-HSA-937059;R-HSA-6798743;R-HSA-9021306;R-HSA-168950;R-HSA-6798739;R-HSA-169719;R-HSA-168951;R-HSA-936952;R-HSA-2559568;R-HSA-937337;R-HSA-6798751;R-HSA-937079;R-HSA-936951;R-HSA-6798749;R-HSA-6798748;R-HSA-6798747;R-HSA-166271;R-HSA-937075;R-HSA-936947;R-HSA-450296;R-HSA-6798745" R-HSA-1643685,"Disease",59,2418,0.16479247597628296,0.9999999986900238,0.9999999986900238,100,1418,0.10939669804042586,9606,Homo sapiens,"CDKN1C;FEN1;SLC40A1;LMNB1;ADAMTS4;FGF5;TUBA1C;TUBB6;TUBA1B;FGF7;ADAMTS3;TUBB3;HIST1H2AE;HIST1H2AD;KPNA2;IL6R;LIG1;HIST1H2AH;HIST1H2AK;TUBB;HIST2H2BB;CDC25C;HIST2H2BF;CDC25A;BTC;NEIL3;CCNE2;HIST1H2BF;SERPING1;HIST1H2BE;HIST1H2BG;DOCK2;HIST1H2BB;HIST1H2BD;HIST1H2BC;HIST1H2BN;HIST1H2BM;HIST1H2BO;HIST1H3J;HIST1H2BJ;HIST1H2BI;HIST1H2BL;HIST1H2BK;HIST2H4A;PORCN;BCL2L11;E2F1;POC1A;CD14;HIST1H3B;MAP2K6;RPL39L;UBE2C;HIST1H4L;TUBB4B;SOD2;HIST1H4B;UBE2S;TBXAS1;CDK2;CDK1;HIST1H4H;HIST1H4C;HIST1H4D;HIST1H4E;EZH2","","R-HSA-2023455;R-HSA-2023451;R-HSA-9659782;R-HCY-9625991;R-HSA-5602383;R-HSA-6791035;R-HSA-9681294;R-HSA-5602672;R-HSA-9664950;R-HSA-2400009;R-HSA-9665699;R-HSA-9665697;R-HSA-9665701;R-HSA-9665700;R-HSA-9665705;R-HSA-8863674;R-HSA-9665709;R-HSA-5211405;R-HSA-9664976;R-HSA-9664983;R-HSA-5655315;R-HSA-9614810;R-HSA-5655326;R-HSA-9614811;R-HSA-192841;R-HSA-9664991;R-HSA-5655323;R-HSA-5655320;R-HSA-2033488;R-HSA-2033486;R-HSA-5655301;R-HSA-2033474;R-HSA-182876;R-HSA-2033472;R-HSA-5602353;R-HSA-9614816;R-HSA-8868340;R-HSA-5655343;R-HSA-6785565;R-HSA-5602606;R-HSA-5655339;R-HSA-5655760;R-HSA-6802927;R-HSA-5655262;R-HSA-5655263;R-HSA-5654748;R-HSA-9614367;R-HSA-6802935;R-HSA-6802934;R-HSA-6802933;R-HSA-9651456;R-HSA-6802932;R-HSA-9614343;R-HSA-5655233;R-HSA-9651467;R-HSA-8870686;R-HSA-5655247;R-HSA-5655244;R-HSA-5655245;R-HSA-9650447;R-HSA-5655243;R-HSA-5655240;R-HSA-5603275;R-HSA-5655241;R-HSA-8863014;R-HSA-5655285;R-HSA-9664567;R-HSA-8863011;R-HSA-8870703;R-HSA-5655295;R-HSA-9623096;R-HSA-5655290;R-HSA-5655289;R-HSA-9629245;R-HSA-5655270;R-HSA-5655268;R-HSA-5655269;R-HSA-2012074;R-HSA-5655266;R-HSA-2012073;R-HSA-5655278;R-HSA-5655277;R-HSA-5340560;R-HSA-9687377;R-HSA-192704;R-HSA-9621073;R-HSA-9652816;R-HSA-5621402;R-HSA-9685830;R-HSA-9664588;R-HSA-1839100;R-HSA-5655733;R-HSA-1839098;R-HSA-1225978;R-HSA-1839094;R-HSA-1176059;R-HSA-2077424;R-HSA-2077421;R-HSA-2077420;R-HSA-200952" R-HSA-382551,"Transport of small molecules",10,963,0.06563075035780004,0.9999999999584438,0.9999999999584438,14,438,0.03379108162320629,9606,Homo sapiens,"SLC7A5;ATP8B4;ABCA6;SLC2A12;SLC40A1;LSR;ABCA8;CLIC2","","R-HSA-429094;R-HSA-8933258;R-HSA-917933;R-HSA-8933292;R-HSA-442368;R-HSA-2855020;R-HSA-1369052;R-HSA-947591;R-HSA-917891;R-HSA-352232;R-HSA-1369028;R-HSA-904830;R-HSA-1467457;R-HSA-939763" R-HSA-556833,"Metabolism of lipids",23,1445,0.09848020173107068,0.9999999999637411,0.9999999999637411,46,943,0.07275111865452862,9606,Homo sapiens,"CERS4;TMEM86A;PPM1L;MCM8;RARRES3;EPHX2;AKR1C1;ELOVL3;CFI;AKR1C3;AKR1C2;PLD1;GLIPR1;DEPDC1B;FABP5;TBXAS1;NES;MFSD2A;PTGES","","R-HSA-1482646;R-HSA-8874435;R-HSA-429699;R-HSA-548814;R-HSA-1602398;R-HSA-548815;R-HSA-548800;R-HSA-2161961;R-HSA-193800;R-HSA-1483142;R-HSA-2046094;R-HSA-1602377;R-HSA-1989772;R-HSA-76500;R-HSA-1482691;R-HSA-1602446;R-HSA-2046088;R-HSA-1482689;R-HSA-1602368;R-HSA-1482636;R-HSA-5334794;R-HSA-193758;R-HSA-2161660;R-HSA-1602374;R-HSA-428185;R-HSA-1483063;R-HSA-429732;R-HSA-192160;R-HSA-8865637;R-HSA-429730;R-HSA-1482546;R-HSA-1482547;R-HSA-192036;R-HSA-9024993;R-HSA-1602417;R-HSA-2161549;R-HSA-2161613;R-HSA-2161614;R-HSA-193841;R-HSA-1482533;R-HSA-429683;R-HSA-193781;R-HSA-1483182;R-HSA-429694;R-HSA-8858298;R-HSA-1482667" R-HSA-418555,"G alpha (s) signalling events",2,605,0.04123219518844135,0.9999999999879465,0.9999999999879465,1,18,0.0013886745872550533,9606,Homo sapiens,"RTP4;REEP4","","R-HSA-381750" R-HSA-388396,"GPCR downstream signalling",16,1359,0.09261909629932528,0.9999999999999195,0.9999999999999195,17,258,0.019904335750655762,9606,Homo sapiens,"RTP4;AKR1C1;TACR2;HTR2B;AKR1C3;PLCB4;PNP;REEP4;RDH10;AGTR1;ARHGEF3;ACKR3;S1PR3;ECT2;KPNA2","","R-HSA-114688;R-HSA-749448;R-HSA-112037;R-HSA-749454;R-HSA-9619127;R-HSA-111879;R-HSA-749452;R-HSA-398188;R-HSA-380073;R-HSA-379048;R-HSA-381750;R-HSA-419166;R-HSA-74872;R-HSA-749456;R-HSA-112282;R-HSA-2855252;R-HSA-111870" R-HSA-8953854,"Metabolism of RNA",2,782,0.05329516799563825,0.9999999999999971,0.9999999999999971,6,187,0.014426785989816386,9606,Homo sapiens,"ISG20;RPL39L","","R-HSA-927836;R-HSA-927789;R-HSA-6791218;R-HSA-927832;R-HSA-927813;R-HSA-927889" R-HSA-372790,"Signaling by GPCR",17,1485,0.10120629728071968,0.9999999999999974,0.9999999999999974,26,437,0.033713933035025456,9606,Homo sapiens,"RTP4;AKR1C1;TACR2;HTR2B;AKR1C3;PLCB4;PNP;ADGRE5;REEP4;RDH10;AGTR1;ARHGEF3;ACKR3;S1PR3;ECT2;KPNA2","","R-HSA-114688;R-HSA-749448;R-HSA-9615249;R-HSA-374214;R-HSA-749454;R-HSA-383363;R-HSA-111879;R-HSA-749452;R-HSA-390930;R-HSA-374173;R-HSA-419166;R-HSA-749456;R-HSA-112282;R-HSA-419428;R-HSA-444773;R-HSA-112037;R-HSA-9619127;R-HSA-398188;R-HSA-380073;R-HSA-379048;R-HSA-381750;R-HSA-879674;R-HSA-74872;R-HSA-388863;R-HSA-2855252;R-HSA-111870" R-HSA-1430728,"Metabolism",50,3650,0.24875621890547264,1.0,1.0,92,2241,0.17288998611325412,9606,Homo sapiens,"PPM1L;MCM8;CFI;XYLT1;HMMR;TYMS;PLD1;AK8;SULT1A1;BRIP1;GLIPR1;PNP;PHKG1;ORC1;KYNU;POLD1;E2F1;CHAC2;TK1;GBP2;ACSS1;PSPH;MFSD2A;RPL39L;CERS4;GSTM3;TMEM86A;RRM2;RARRES3;EPHX2;AKR1C1;ELOVL3;AKR1C3;AKR1C2;HOGA1;INMT;SLC7A5;DEPDC1B;PLCB4;FABP5;TBXAS1;NAGS;NES;PTGES","","R-HSA-1482646;R-HSA-158849;R-HSA-74242;R-HSA-176646;R-HSA-73605;R-HSA-429699;R-HSA-6799202;R-HSA-158468;R-HSA-111751;R-HSA-74249;R-HSA-2161961;R-HSA-193800;R-HSA-158860;R-HSA-70542;R-HSA-1483142;R-HSA-2046094;R-HSA-1989772;R-HSA-163217;R-HSA-1602446;R-HSA-2046088;R-HSA-1482636;R-HSA-176669;R-HSA-428185;R-HSA-112033;R-HSA-1483063;R-HSA-73632;R-HSA-429732;R-HSA-192160;R-HSA-977324;R-HSA-112034;R-HSA-429730;R-HSA-1482546;R-HSA-1482547;R-HSA-192036;R-HSA-6799179;R-HSA-2161549;R-HSA-71217;R-HSA-6799191;R-HSA-193841;R-HSA-2160915;R-HSA-1482533;R-HSA-176054;R-HSA-1483182;R-HSA-110137;R-HSA-6799197;R-HSA-110138;R-HSA-6799196;R-HSA-8858298;R-HSA-1482667;R-HSA-5333615;R-HSA-6784423;R-HSA-8874435;R-HSA-548814;R-HSA-1602398;R-HSA-548815;R-HSA-548800;R-HSA-176585;R-HSA-2408554;R-HSA-1602377;R-HSA-2160884;R-HSA-76500;R-HSA-1482691;R-HSA-1855177;R-HSA-1482689;R-HSA-176474;R-HSA-1602368;R-HSA-5334794;R-HSA-193758;R-HSA-2161660;R-HSA-2160892;R-HSA-1602374;R-HSA-453337;R-HSA-351207;R-HSA-8865637;R-HSA-9024993;R-HSA-1602417;R-HSA-70634;R-HSA-351208;R-HSA-352232;R-HSA-2161613;R-HSA-2161614;R-HSA-1878002;R-HSA-6785928;R-HSA-449911;R-HSA-71541;R-HSA-429683;R-HSA-2408529;R-HSA-193781;R-HSA-429694;R-HSA-2564828;R-HSA-2855252;R-HSA-111742"