residue,amino_acid,num_mutants,mutant,endogenous_ligand_wt_ks,endogenous_ligand_mut_ks,drug_wt_ks,drug_mut_ks,sig_prob,codon 718,leu,21,ALA,19.047,18.431,25.258,23.94,2.6605E-05,GCTGG 718,leu,21,ARG,19.047,19.409,25.258,22.502,0.00237855,GCTGG 718,leu,21,ASN,19.047,18.58,25.258,23.905,0,GCTGG 718,leu,21,ASP,19.047,18.382,25.258,22.751,0,GCTGG 718,leu,21,CYS,19.047,18.573,25.258,23.922,0,GCTGG 718,leu,21,GLN,19.047,18.743,25.258,24.465,0.013844436,GCTGG 718,leu,21,GLU,19.047,18.518,25.258,24.047,5.63791E-05,GCTGG 718,leu,21,GLY,19.047,18.146,25.258,nan,8.4912E-06,GCTGG 718,leu,21,HID,19.047,18.896,25.258,-60.92,0.000420078,GCTGG 718,leu,21,HIE,19.047,18.917,25.258,-61.903,0.000420078,GCTGG 718,leu,21,HIP,19.047,18.858,25.258,-62.439,0.000420078,GCTGG 718,leu,21,ILE,19.047,19.354,25.258,24.007,0.000739154,GCTGG 718,leu,21,LYS,19.047,19.222,25.258,22.977,0.000269724,GCTGG 718,leu,21,MET,19.047,19.436,25.258,24.628,0.010765658,GCTGG 718,leu,21,PHE,19.047,17.162,25.258,nan,0.000246577,GCTGG 718,leu,21,PRO,19.047,nan,25.258,nan,0.005231454,GCTGG 718,leu,21,SER,19.047,18.483,25.258,23.891,3.71285E-05,GCTGG 718,leu,21,THR,19.047,18.989,25.258,23.976,0.000133858,GCTGG 718,leu,21,TRP,19.047,17.961,25.258,nan,1.74828E-05,GCTGG 718,leu,21,TYR,19.047,15.322,25.258,nan,0,GCTGG 718,leu,21,VAL,19.047,19.136,25.258,23.624,0.002992341,GCTGG 719,gly,21,ALA,19.05,19.327,25.247,25.346,0.00409667,GGGCT 719,gly,21,ARG,19.05,15.787,25.247,25.102,0.004558455,GGGCT 719,gly,21,ASN,19.05,19.341,25.247,25.548,6.9696E-05,GGGCT 719,gly,21,ASP,19.05,19.148,25.247,25.365,0.005323593,GGGCT 719,gly,21,CYS,19.05,18.621,25.247,25.549,0.024673821,GGGCT 719,gly,21,GLN,19.05,17.869,25.247,25.66,0,GGGCT 719,gly,21,GLU,19.05,16.716,25.247,24.25,0.000153849,GGGCT 719,gly,21,HID,19.05,19.787,25.247,25.672,4.66395E-05,GGGCT 719,gly,21,HIE,19.05,19.794,25.247,25.714,4.66395E-05,GGGCT 719,gly,21,HIP,19.05,19.447,25.247,25.634,4.66395E-05,GGGCT 719,gly,21,ILE,19.05,16.147,25.247,25.791,0.000147605,GGGCT 719,gly,21,LEU,19.05,15.917,25.247,25.481,7.87309E-05,GGGCT 719,gly,21,LYS,19.05,16.554,25.247,25.138,0,GGGCT 719,gly,21,MET,19.05,18.046,25.247,24.928,0,GGGCT 719,gly,21,PHE,19.05,2.036,25.247,25.757,0.000598835,GGGCT 719,gly,21,PRO,19.05,nan,25.247,nan,2.49733E-05,GGGCT 719,gly,21,SER,19.05,19.226,25.247,25.496,0.007639723,GGGCT 719,gly,21,THR,19.05,17.76,25.247,25.601,4.02065E-05,GGGCT 719,gly,21,TRP,19.05,20.272,25.247,26.162,0.000135479,GGGCT 719,gly,21,TYR,19.05,-141.778,25.247,25.773,0.000246858,GGGCT 719,gly,21,VAL,19.05,14.699,25.247,25.679,0.017012902,GGGCT 723,phe,21,ALA,19.059,18.976,25.203,nan,5.71617E-07,GTTCG 723,phe,21,ARG,19.059,19.151,25.203,25.086,2.94074E-06,GTTCG 723,phe,21,ASN,19.059,19.108,25.203,25.075,1.18577E-05,GTTCG 723,phe,21,ASP,19.059,18.981,25.203,nan,8.40959E-07,GTTCG 723,phe,21,CYS,19.059,19.075,25.203,25.064,0.000509646,GTTCG 723,phe,21,GLN,19.059,19.076,25.203,25.102,0,GTTCG 723,phe,21,GLU,19.059,19.037,25.203,24.922,0,GTTCG 723,phe,21,GLY,19.059,18.906,25.203,nan,5.91554E-07,GTTCG 723,phe,21,HID,19.059,19.511,25.203,25.151,1.86124E-05,GTTCG 723,phe,21,HIE,19.059,19.608,25.203,25.145,1.86124E-05,GTTCG 723,phe,21,HIP,19.059,19.456,25.203,25.126,1.86124E-05,GTTCG 723,phe,21,ILE,19.059,19.5,25.203,25.095,0.002092108,GTTCG 723,phe,21,LEU,19.059,19.054,25.203,nan,0.008273152,GTTCG 723,phe,21,LYS,19.059,19.07,25.203,25.153,0,GTTCG 723,phe,21,MET,19.059,19.077,25.203,25.131,5.84745E-06,GTTCG 723,phe,21,PRO,19.059,nan,25.203,nan,6.72335E-06,GTTCG 723,phe,21,SER,19.059,19.046,25.203,25.225,0.001662424,GTTCG 723,phe,21,THR,19.059,19.073,25.203,25.131,7.48668E-06,GTTCG 723,phe,21,TRP,19.059,19.006,25.203,25.223,3.38381E-06,GTTCG 723,phe,21,TYR,19.059,19.486,25.203,25.203,0.00239425,GTTCG 723,phe,21,VAL,19.059,19.137,25.203,nan,0.000315569,GTTCG 726,val,21,ALA,19.042,17.356,25.242,24.109,0.0026951,GGTGT 726,val,21,ARG,19.042,17.682,25.242,25.188,2.31722E-05,GGTGT 726,val,21,ASN,19.042,18.168,25.242,24.854,0,GGTGT 726,val,21,ASP,19.042,18.321,25.242,24.405,0.000111561,GGTGT 726,val,21,CYS,19.042,18.384,25.242,24.678,0,GGTGT 726,val,21,GLN,19.042,17.55,25.242,24.508,6.51014E-05,GGTGT 726,val,21,GLU,19.042,17.131,25.242,24.03,0.005493485,GGTGT 726,val,21,GLY,19.042,16.966,25.242,23.723,0.001214228,GGTGT 726,val,21,HID,19.042,15.23,25.242,nan,0,GGTGT 726,val,21,HIE,19.042,15.311,25.242,nan,0,GGTGT 726,val,21,HIP,19.042,15.102,25.242,nan,0,GGTGT 726,val,21,ILE,19.042,19.215,25.242,25.929,0.000231658,GGTGT 726,val,21,LEU,19.042,18.832,25.242,26.208,0.015822068,GGTGT 726,val,21,LYS,19.042,17.073,25.242,25.539,5.38732E-05,GGTGT 726,val,21,MET,19.042,17.374,25.242,24.987,0.004377751,GGTGT 726,val,21,PHE,19.042,19.71,25.242,nan,0.000508642,GGTGT 726,val,21,PRO,19.042,nan,25.242,nan,2.30335E-05,GGTGT 726,val,21,SER,19.042,17.512,25.242,24.205,6.91646E-05,GGTGT 726,val,21,THR,19.042,18.404,25.242,24.825,3.46983E-05,GGTGT 726,val,21,TRP,19.042,19.508,25.242,nan,4.82055E-05,GGTGT 726,val,21,TYR,19.042,19.198,25.242,nan,0,GGTGT 743,ala,21,ARG,19.144,6.55,25.215,nan,1.72609E-05,CGCTA 743,ala,21,ASN,19.144,nan,25.215,nan,8.62891E-05,CGCTA 743,ala,21,ASP,19.144,13.507,25.215,nan,0.010877882,CGCTA 743,ala,21,CYS,19.144,14.53,25.215,nan,7.33747E-05,CGCTA 743,ala,21,GLN,19.144,2.021,25.215,nan,0,CGCTA 743,ala,21,GLU,19.144,4.169,25.215,nan,7.74053E-05,CGCTA 743,ala,21,GLY,19.144,18.318,25.215,24.213,0.002839546,CGCTA 743,ala,21,HID,19.144,nan,25.215,nan,5.86845E-05,CGCTA 743,ala,21,HIE,19.144,nan,25.215,nan,5.86845E-05,CGCTA 743,ala,21,HIP,19.144,nan,25.215,nan,5.86845E-05,CGCTA 743,ala,21,ILE,19.144,nan,25.215,nan,4.83521E-05,CGCTA 743,ala,21,LEU,19.144,nan,25.215,nan,3.08832E-05,CGCTA 743,ala,21,LYS,19.144,5.345,25.215,nan,0,CGCTA 743,ala,21,MET,19.144,6.995,25.215,nan,0,CGCTA 743,ala,21,PHE,19.144,nan,25.215,nan,0.000110056,CGCTA 743,ala,21,PRO,19.144,nan,25.215,nan,0.002475763,CGCTA 743,ala,21,SER,19.144,18.542,25.215,25.303,0.009101153,CGCTA 743,ala,21,THR,19.144,nan,25.215,nan,0.004569261,CGCTA 743,ala,21,TRP,19.144,nan,25.215,nan,0,CGCTA 743,ala,21,TYR,19.144,nan,25.215,nan,0.000194242,CGCTA 743,ala,21,VAL,19.144,nan,25.215,nan,0.005289747,CGCTA 744,ile,21,ALA,18.969,nan,25.189,25.143,1.54904E-05,TATCA 744,ile,21,ARG,18.969,18.974,25.189,25.168,1.09905E-05,TATCA 744,ile,21,ASN,18.969,18.968,25.189,25.19,0.00256233,TATCA 744,ile,21,ASP,18.969,nan,25.189,25.175,1.93634E-05,TATCA 744,ile,21,CYS,18.969,18.963,25.189,25.179,1.75077E-06,TATCA 744,ile,21,GLN,18.969,18.982,25.189,25.201,0,TATCA 744,ile,21,GLU,18.969,18.977,25.189,25.191,0,TATCA 744,ile,21,GLY,18.969,nan,25.189,25.114,1.04583E-06,TATCA 744,ile,21,HID,18.969,nan,25.189,25.214,1.0467E-06,TATCA 744,ile,21,HIE,18.969,nan,25.189,25.184,1.0467E-06,TATCA 744,ile,21,HIP,18.969,nan,25.189,25.201,1.0467E-06,TATCA 744,ile,21,LEU,18.969,nan,25.189,25.203,0.000267563,TATCA 744,ile,21,LYS,18.969,18.979,25.189,25.141,0.000109415,TATCA 744,ile,21,MET,18.969,18.973,25.189,25.204,0.005383161,TATCA 744,ile,21,PHE,18.969,nan,25.189,25.211,0.002520041,TATCA 744,ile,21,PRO,18.969,nan,25.189,nan,3.73778E-07,TATCA 744,ile,21,SER,18.969,nan,25.189,25.171,0.00021789,TATCA 744,ile,21,THR,18.969,18.971,25.189,25.183,0.002065514,TATCA 744,ile,21,TRP,18.969,nan,25.189,25.228,0,TATCA 744,ile,21,TYR,18.969,nan,25.189,25.219,1.11726E-05,TATCA 744,ile,21,VAL,18.969,18.947,25.189,25.173,0.006543451,TATCA 745,lys,21,ALA,18.982,nan,25.182,nan,4.68835E-06,CAAGG 745,lys,21,ARG,18.982,19.187,25.182,24.91,0.003668577,CAAGG 745,lys,21,ASN,18.982,nan,25.182,nan,0.022192852,CAAGG 745,lys,21,ASP,18.982,nan,25.182,nan,9.44453E-05,CAAGG 745,lys,21,CYS,18.982,nan,25.182,nan,0,CAAGG 745,lys,21,GLN,18.982,nan,25.182,nan,0.001577689,CAAGG 745,lys,21,GLU,18.982,nan,25.182,nan,0.002194491,CAAGG 745,lys,21,GLY,18.982,nan,25.182,nan,2.22563E-05,CAAGG 745,lys,21,HID,18.982,18.81,25.182,nan,6.75642E-05,CAAGG 745,lys,21,HIE,18.982,18.846,25.182,nan,6.75642E-05,CAAGG 745,lys,21,HIP,18.982,18.836,25.182,24.464,6.75642E-05,CAAGG 745,lys,21,ILE,18.982,19.046,25.182,nan,0.000243299,CAAGG 745,lys,21,LEU,18.982,nan,25.182,nan,6.03781E-05,CAAGG 745,lys,21,MET,18.982,18.975,25.182,nan,0.005158684,CAAGG 745,lys,21,PHE,18.982,18.936,25.182,nan,0,CAAGG 745,lys,21,PRO,18.982,nan,25.182,nan,4.70537E-06,CAAGG 745,lys,21,SER,18.982,nan,25.182,nan,0.000192388,CAAGG 745,lys,21,THR,18.982,18.71,25.182,nan,0.001263189,CAAGG 745,lys,21,TRP,18.982,nan,25.182,nan,5.89524E-05,CAAGG 745,lys,21,TYR,18.982,nan,25.182,nan,0.000152152,CAAGG 745,lys,21,VAL,18.982,nan,25.182,nan,3.52128E-05,CAAGG 766,met,21,ALA,19.053,nan,25.156,24.688,1.20362E-05,GATGG 766,met,21,ARG,19.053,19.057,25.156,24.144,0.001012196,GATGG 766,met,21,ASN,19.053,nan,25.156,24.745,0.000153575,GATGG 766,met,21,ASP,19.053,nan,25.156,24.598,0,GATGG 766,met,21,CYS,19.053,nan,25.156,24.738,0,GATGG 766,met,21,GLN,19.053,19.043,25.156,24.952,4.91244E-06,GATGG 766,met,21,GLU,19.053,nan,25.156,24.729,1.75663E-05,GATGG 766,met,21,GLY,19.053,nan,25.156,24.699,4.06076E-06,GATGG 766,met,21,HID,19.053,nan,25.156,24.921,0,GATGG 766,met,21,HIE,19.053,nan,25.156,24.976,0,GATGG 766,met,21,HIP,19.053,nan,25.156,24.87,0,GATGG 766,met,21,ILE,19.053,nan,25.156,24.941,0.034580808,GATGG 766,met,21,LEU,19.053,nan,25.156,25.009,0.002795343,GATGG 766,met,21,LYS,19.053,19.005,25.156,23.867,0.004798811,GATGG 766,met,21,PHE,19.053,nan,25.156,25.044,0.000119217,GATGG 766,met,21,PRO,19.053,nan,25.156,24.741,1.36673E-06,GATGG 766,met,21,SER,19.053,19.02,25.156,24.696,5.33293E-05,GATGG 766,met,21,THR,19.053,nan,25.156,24.715,0.005153904,GATGG 766,met,21,TRP,19.053,nan,25.156,21.333,8.46467E-06,GATGG 766,met,21,TYR,19.053,nan,25.156,24.966,0,GATGG 766,met,21,VAL,19.053,nan,25.156,24.761,0.001972545,GATGG 777,leu,21,ALA,19.049,nan,25.213,25.104,3.16048E-05,CCTGC 777,leu,21,ARG,19.049,19.049,25.213,25.127,0.002345714,CCTGC 777,leu,21,ASN,19.049,19.057,25.213,25.137,0,CCTGC 777,leu,21,ASP,19.049,nan,25.213,25.085,0,CCTGC 777,leu,21,CYS,19.049,nan,25.213,25.122,0,CCTGC 777,leu,21,GLN,19.049,nan,25.213,25.109,0.013763786,CCTGC 777,leu,21,GLU,19.049,nan,25.213,25.142,8.34675E-05,CCTGC 777,leu,21,GLY,19.049,nan,25.213,25.089,1.04298E-05,CCTGC 777,leu,21,HID,19.049,19.043,25.213,25.177,0.000280636,CCTGC 777,leu,21,HIE,19.049,19.061,25.213,25.122,0.000280636,CCTGC 777,leu,21,HIP,19.049,nan,25.213,25.174,0.000280636,CCTGC 777,leu,21,ILE,19.049,nan,25.213,25.141,0.000874882,CCTGC 777,leu,21,LYS,19.049,19.063,25.213,25.13,0.000347942,CCTGC 777,leu,21,MET,19.049,19.055,25.213,25.16,0.017910405,CCTGC 777,leu,21,PHE,19.049,nan,25.213,25.511,0.000379173,CCTGC 777,leu,21,PRO,19.049,nan,25.213,25.117,0.005218437,CCTGC 777,leu,21,SER,19.049,nan,25.213,25.111,5.77575E-05,CCTGC 777,leu,21,THR,19.049,nan,25.213,25.13,0.000210364,CCTGC 777,leu,21,TRP,19.049,nan,25.213,25.155,2.87535E-05,CCTGC 777,leu,21,TYR,19.049,nan,25.213,25.617,0,CCTGC 777,leu,21,VAL,19.049,nan,25.213,25.142,0.004487629,CCTGC 788,leu,21,ALA,18.98,nan,25.173,24.892,1.16199E-05,GCTCA 788,leu,21,ARG,18.98,nan,25.173,21.814,0.000819356,GCTCA 788,leu,21,ASN,18.98,nan,25.173,24.972,0.000102872,GCTCA 788,leu,21,ASP,18.98,nan,25.173,24.834,2.07362E-05,GCTCA 788,leu,21,CYS,18.98,nan,25.173,25.001,5.84954E-06,GCTCA 788,leu,21,GLN,18.98,18.921,25.173,25.084,0.000211704,GCTCA 788,leu,21,GLU,18.98,18.986,25.173,24.967,0,GCTCA 788,leu,21,GLY,18.98,nan,25.173,24.767,2.05553E-06,GCTCA 788,leu,21,HID,18.98,nan,25.173,25.019,0.004858752,GCTCA 788,leu,21,HIE,18.98,nan,25.173,25.046,0.004858752,GCTCA 788,leu,21,HIP,18.98,nan,25.173,25.043,0.004858752,GCTCA 788,leu,21,ILE,18.98,nan,25.173,24.13,0.011286177,GCTCA 788,leu,21,LYS,18.98,18.959,25.173,25.27,0,GCTCA 788,leu,21,MET,18.98,18.983,25.173,25.309,0.000114988,GCTCA 788,leu,21,PHE,18.98,nan,25.173,25.048,0.00533374,GCTCA 788,leu,21,PRO,18.98,nan,25.173,nan,0.002122773,GCTCA 788,leu,21,SER,18.98,nan,25.173,24.885,2.72663E-05,GCTCA 788,leu,21,THR,18.98,nan,25.173,24.542,5.1136E-05,GCTCA 788,leu,21,TRP,18.98,nan,25.173,22.088,0,GCTCA 788,leu,21,TYR,18.98,nan,25.173,25.054,3.76697E-05,GCTCA 788,leu,21,VAL,18.98,nan,25.173,22.7,0.002965523,GCTCA 790,thr,21,ALA,19.139,19.062,25.173,25.226,0.00267405,CACGC 790,thr,21,ARG,19.139,19.324,25.173,11.397,0.001385534,CACGC 790,thr,21,ASN,19.139,19.157,25.173,21.867,0.00021892,CACGC 790,thr,21,ASP,19.139,nan,25.173,nan,0,CACGC 790,thr,21,CYS,19.139,19.121,25.173,24.998,0,CACGC 790,thr,21,GLN,19.139,nan,25.173,21.571,1.54147E-05,CACGC 790,thr,21,GLU,19.139,nan,25.173,19.735,3.85592E-05,CACGC 790,thr,21,GLY,19.139,18.876,25.173,24.638,1.29028E-05,CACGC 790,thr,21,HID,19.139,nan,25.173,nan,0,CACGC 790,thr,21,HIE,19.139,nan,25.173,nan,0,CACGC 790,thr,21,HIP,19.139,nan,25.173,nan,0,CACGC 790,thr,21,ILE,19.139,18.627,25.173,24.732,0.000222943,CACGC 790,thr,21,LEU,19.139,nan,25.173,nan,6.21034E-05,CACGC 790,thr,21,LYS,19.139,19.542,25.173,22.011,0.00737665,CACGC 790,thr,21,MET,19.139,19.788,25.173,23.886,0.006016789,CACGC 790,thr,21,PHE,19.139,nan,25.173,nan,0,CACGC 790,thr,21,PRO,19.139,nan,25.173,nan,0.001222561,CACGC 790,thr,21,SER,19.139,19.087,25.173,25.187,0.005680542,CACGC 790,thr,21,TRP,19.139,nan,25.173,nan,2.58254E-05,CACGC 790,thr,21,TYR,19.139,nan,25.173,nan,0,CACGC 790,thr,21,VAL,19.139,nan,25.173,25.478,4.07658E-05,CACGC 791,gln,21,ALA,19.115,19.077,25.187,25.157,1.06483E-05,GCAGC 791,gln,21,ARG,19.115,19.132,25.187,25.285,0.005360332,GCAGC 791,gln,21,ASN,19.115,19.107,25.187,25.186,0.000434941,GCAGC 791,gln,21,ASP,19.115,19.081,25.187,25.102,8.18894E-05,GCAGC 791,gln,21,CYS,19.115,19.118,25.187,25.177,0,GCAGC 791,gln,21,GLU,19.115,19.168,25.187,25.174,0.003085482,GCAGC 791,gln,21,GLY,19.115,19.061,25.187,nan,1.80709E-05,GCAGC 791,gln,21,HID,19.115,19.144,25.187,25.198,0.013566748,GCAGC 791,gln,21,HIE,19.115,19.144,25.187,25.194,0.013566748,GCAGC 791,gln,21,HIP,19.115,19.135,25.187,25.207,0.013566748,GCAGC 791,gln,21,ILE,19.115,19.187,25.187,25.212,0,GCAGC 791,gln,21,LEU,19.115,19.122,25.187,25.182,0.014181679,GCAGC 791,gln,21,LYS,19.115,19.098,25.187,nan,0.016282596,GCAGC 791,gln,21,MET,19.115,19.132,25.187,25.246,0.000228398,GCAGC 791,gln,21,PHE,19.115,19.147,25.187,25.207,0,GCAGC 791,gln,21,PRO,19.115,19.22,25.187,nan,0.002299742,GCAGC 791,gln,21,SER,19.115,19.126,25.187,25.263,1.17485E-05,GCAGC 791,gln,21,THR,19.115,19.172,25.187,25.227,5.39053E-05,GCAGC 791,gln,21,TRP,19.115,19.241,25.187,25.213,3.76265E-05,GCAGC 791,gln,21,TYR,19.115,19.176,25.187,25.208,0.000146521,GCAGC 791,gln,21,VAL,19.115,19.179,25.187,25.191,5.2238E-05,GCAGC 792,leu,21,ALA,19.033,nan,25.164,24.505,1.16199E-05,GCTCA 792,leu,21,ARG,19.033,18.754,25.164,24.709,0.000819356,GCTCA 792,leu,21,ASN,19.033,18.812,25.164,24.872,0.000102872,GCTCA 792,leu,21,ASP,19.033,18.69,25.164,24.609,2.07362E-05,GCTCA 792,leu,21,CYS,19.033,18.658,25.164,24.655,5.84954E-06,GCTCA 792,leu,21,GLN,19.033,18.231,25.164,24.134,0.000211704,GCTCA 792,leu,21,GLU,19.033,18.723,25.164,24.693,0,GCTCA 792,leu,21,GLY,19.033,nan,25.164,24.383,2.05553E-06,GCTCA 792,leu,21,HID,19.033,18.985,25.164,25.288,0.004858752,GCTCA 792,leu,21,HIE,19.033,18.932,25.164,25.258,0.004858752,GCTCA 792,leu,21,HIP,19.033,18.885,25.164,25.213,0.004858752,GCTCA 792,leu,21,ILE,19.033,nan,25.164,24.951,0.011286177,GCTCA 792,leu,21,LYS,19.033,nan,25.164,24.451,0,GCTCA 792,leu,21,MET,19.033,19.174,25.164,25.09,0.000114988,GCTCA 792,leu,21,PHE,19.033,nan,25.164,25.516,0.00533374,GCTCA 792,leu,21,PRO,19.033,nan,25.164,24.594,0.002122773,GCTCA 792,leu,21,SER,19.033,18.59,25.164,24.561,2.72663E-05,GCTCA 792,leu,21,THR,19.033,nan,25.164,24.726,5.1136E-05,GCTCA 792,leu,21,TRP,19.033,nan,25.164,26.024,0,GCTCA 792,leu,21,TYR,19.033,nan,25.164,25.846,3.76697E-05,GCTCA 792,leu,21,VAL,19.033,nan,25.164,24.802,0.002965523,GCTCA 793,met,21,ALA,19.043,nan,25.164,nan,2.54701E-05,CATGC 793,met,21,ARG,19.043,nan,25.164,nan,0.001012558,CATGC 793,met,21,ASN,19.043,18.932,25.164,nan,0.000103534,CATGC 793,met,21,ASP,19.043,nan,25.164,nan,0,CATGC 793,met,21,CYS,19.043,nan,25.164,nan,0,CATGC 793,met,21,GLN,19.043,18.96,25.164,25.139,2.05437E-05,CATGC 793,met,21,GLU,19.043,nan,25.164,25.123,3.67572E-05,CATGC 793,met,21,GLY,19.043,nan,25.164,nan,1.06819E-05,CATGC 793,met,21,HID,19.043,19.081,25.164,25.193,0,CATGC 793,met,21,HIE,19.043,19.077,25.164,nan,0,CATGC 793,met,21,HIP,19.043,19.056,25.164,nan,0,CATGC 793,met,21,ILE,19.043,nan,25.164,nan,0.024692569,CATGC 793,met,21,LEU,19.043,nan,25.164,nan,0.005828528,CATGC 793,met,21,LYS,19.043,nan,25.164,nan,0.004764334,CATGC 793,met,21,PHE,19.043,nan,25.164,nan,0.000178937,CATGC 793,met,21,PRO,19.043,nan,25.164,nan,1.06819E-05,CATGC 793,met,21,SER,19.043,nan,25.164,nan,6.3361E-05,CATGC 793,met,21,THR,19.043,nan,25.164,nan,0.005121856,CATGC 793,met,21,TRP,19.043,nan,25.164,nan,2.05437E-05,CATGC 793,met,21,TYR,19.043,18.089,25.164,nan,0,CATGC 793,met,21,VAL,19.043,nan,25.164,nan,0.005180485,CATGC 794,pro,21,ALA,19.034,nan,25.144,25.115,0.00413637,GCCCT 794,pro,21,ARG,19.034,nan,25.144,25.206,0.004416419,GCCCT 794,pro,21,ASN,19.034,nan,25.144,25.143,0.000598835,GCCCT 794,pro,21,ASP,19.034,nan,25.144,25.081,0.000136019,GCCCT 794,pro,21,CYS,19.034,19.008,25.144,25.12,4.66395E-05,GCCCT 794,pro,21,GLN,19.034,nan,25.144,25.21,0.000676298,GCCCT 794,pro,21,GLU,19.034,19.065,25.144,25.135,0,GCCCT 794,pro,21,GLY,19.034,nan,25.144,25.043,2.49733E-05,GCCCT 794,pro,21,HID,19.034,19.035,25.144,25.17,0.02469552,GCCCT 794,pro,21,HIE,19.034,19.055,25.144,25.168,0.02469552,GCCCT 794,pro,21,HIP,19.034,nan,25.144,25.156,0.02469552,GCCCT 794,pro,21,ILE,19.034,nan,25.144,25.236,0.000147605,GCCCT 794,pro,21,LEU,19.034,nan,25.144,25.263,0.007970696,GCCCT 794,pro,21,LYS,19.034,nan,25.144,25.191,0,GCCCT 794,pro,21,MET,19.034,19.016,25.144,25.208,0,GCCCT 794,pro,21,PHE,19.034,19.016,25.144,25.241,6.9696E-05,GCCCT 794,pro,21,SER,19.034,19.01,25.144,25.114,0.005690332,GCCCT 794,pro,21,THR,19.034,19.061,25.144,25.13,0.017161004,GCCCT 794,pro,21,TRP,19.034,19.044,25.144,25.791,0,GCCCT 794,pro,21,TYR,19.034,19.055,25.144,25.184,0.000246858,GCCCT 794,pro,21,VAL,19.034,nan,25.144,25.208,4.02065E-05,GCCCT 796,gly,21,ALA,18.987,19.161,25.424,24.354,0.00409667,CGGCT 796,gly,21,ARG,18.987,19.54,25.424,9.359,0.002859214,CGGCT 796,gly,21,ASN,18.987,19.36,25.424,20.995,5.2505E-05,CGGCT 796,gly,21,ASP,18.987,19.147,25.424,18.29,0.005323593,CGGCT 796,gly,21,CYS,18.987,19.277,25.424,21.711,0.00383613,CGGCT 796,gly,21,GLN,18.987,19.408,25.424,-12.903,0,CGGCT 796,gly,21,GLU,18.987,18.876,25.424,1.164,0.000153849,CGGCT 796,gly,21,HID,18.987,19.492,25.424,24.122,1.87633E-05,CGGCT 796,gly,21,HIE,18.987,19.545,25.424,23.677,1.87633E-05,CGGCT 796,gly,21,HIP,18.987,19.463,25.424,24.426,1.87633E-05,CGGCT 796,gly,21,ILE,18.987,nan,25.424,nan,0.000163125,CGGCT 796,gly,21,LEU,18.987,19.552,25.424,-25.461,4.41339E-05,CGGCT 796,gly,21,LYS,18.987,19.424,25.424,7.618,0,CGGCT 796,gly,21,MET,18.987,19.713,25.424,11.992,0,CGGCT 796,gly,21,PHE,18.987,19.482,25.424,4.68,0.000175861,CGGCT 796,gly,21,PRO,18.987,nan,25.424,nan,1.558E-05,CGGCT 796,gly,21,SER,18.987,19.226,25.424,22.241,0.006427621,CGGCT 796,gly,21,THR,18.987,19.277,25.424,16.875,3.4458E-05,CGGCT 796,gly,21,TRP,18.987,19.127,25.424,nan,2.05504E-05,CGGCT 796,gly,21,TYR,18.987,19.484,25.424,-13.32,4.34046E-05,CGGCT 796,gly,21,VAL,18.987,nan,25.424,nan,0.017012902,CGGCT 797,cys,21,ALA,19.018,18.885,25.492,25.396,1.06483E-05,CTGCC 797,cys,21,ARG,19.018,17.813,25.492,25.542,0.005857603,CTGCC 797,cys,21,ASN,19.018,19.136,25.492,25.525,8.72597E-05,CTGCC 797,cys,21,ASP,19.018,nan,25.492,nan,1.17485E-05,CTGCC 797,cys,21,GLN,19.018,19.211,25.492,25.688,0,CTGCC 797,cys,21,GLU,19.018,19.084,25.492,25.439,0,CTGCC 797,cys,21,GLY,19.018,18.643,25.492,25.307,0.002352716,CTGCC 797,cys,21,HID,19.018,nan,25.492,26.581,3.76265E-05,CTGCC 797,cys,21,HIE,19.018,nan,25.492,26.457,3.76265E-05,CTGCC 797,cys,21,HIP,19.018,nan,25.492,26.345,3.76265E-05,CTGCC 797,cys,21,ILE,19.018,nan,25.492,25.875,0.000228398,CTGCC 797,cys,21,LEU,19.018,nan,25.492,nan,0.000858176,CTGCC 797,cys,21,LYS,19.018,16.736,25.492,25.718,0,CTGCC 797,cys,21,MET,19.018,17.268,25.492,26.17,0,CTGCC 797,cys,21,PHE,19.018,nan,25.492,nan,0.016295542,CTGCC 797,cys,21,PRO,19.018,19.135,25.492,26.487,1.80709E-05,CTGCC 797,cys,21,SER,19.018,18.946,25.492,25.432,0.017106763,CTGCC 797,cys,21,THR,19.018,19.115,25.492,25.683,5.2238E-05,CTGCC 797,cys,21,TRP,19.018,nan,25.492,nan,0.003889464,CTGCC 797,cys,21,TYR,19.018,nan,25.492,26.631,0.005581872,CTGCC 797,cys,21,VAL,19.018,nan,25.492,25.68,5.39053E-05,CTGCC 800,asp,21,ALA,19.06,19.165,25.212,25.295,9.95768E-05,GGACT 800,asp,21,ARG,19.06,19.178,25.212,25.461,2.02511E-05,GGACT 800,asp,21,ASN,19.06,19.179,25.212,25.327,0.006406449,GGACT 800,asp,21,CYS,19.06,19.183,25.212,25.354,0.00011265,GGACT 800,asp,21,GLN,19.06,19.194,25.212,25.325,0.000141623,GGACT 800,asp,21,GLU,19.06,19.15,25.212,25.304,0.012996163,GGACT 800,asp,21,GLY,19.06,19.135,25.212,nan,0.001532372,GGACT 800,asp,21,HID,19.06,19.248,25.212,25.347,0.00559826,GGACT 800,asp,21,HIE,19.06,19.219,25.212,25.38,0.00559826,GGACT 800,asp,21,HIP,19.06,19.203,25.212,25.378,0.00559826,GGACT 800,asp,21,ILE,19.06,19.296,25.212,25.684,2.26077E-05,GGACT 800,asp,21,LEU,19.06,19.227,25.212,25.398,3.56772E-05,GGACT 800,asp,21,LYS,19.06,19.192,25.212,25.318,0.000160498,GGACT 800,asp,21,MET,19.06,19.306,25.212,25.495,0,GGACT 800,asp,21,PHE,19.06,19.289,25.212,25.526,9.40816E-05,GGACT 800,asp,21,PRO,19.06,nan,25.212,nan,6.70937E-06,GGACT 800,asp,21,SER,19.06,19.165,25.212,25.308,2.72422E-05,GGACT 800,asp,21,THR,19.06,19.162,25.212,25.362,2.27465E-06,GGACT 800,asp,21,TRP,19.06,19.479,25.212,25.435,0,GGACT 800,asp,21,TYR,19.06,19.187,25.212,25.422,0.022384453,GGACT 800,asp,21,VAL,19.06,19.168,25.212,25.483,0.002455766,GGACT 842,asn,21,ALA,19.085,18.876,25.116,25.195,5.71617E-07,GAACG 842,asn,21,ARG,19.085,16.528,25.116,25.254,4.87474E-05,GAACG 842,asn,21,ASP,19.085,18.912,25.116,25.179,0.001637687,GAACG 842,asn,21,CYS,19.085,18.943,25.116,25.223,1.86124E-05,GAACG 842,asn,21,GLN,19.085,19.378,25.116,25.256,8.30453E-06,GAACG 842,asn,21,GLU,19.085,18.737,25.116,25.283,2.76535E-05,GAACG 842,asn,21,GLY,19.085,18.58,25.116,25.144,6.72335E-06,GAACG 842,asn,21,HID,19.085,18.597,25.116,25.231,0.000508247,GAACG 842,asn,21,HIE,19.085,18.608,25.116,25.254,0.000508247,GAACG 842,asn,21,HIP,19.085,18.571,25.116,25.237,0.000508247,GAACG 842,asn,21,ILE,19.085,19.09,25.116,25.215,0.002104308,GAACG 842,asn,21,LEU,19.085,19.385,25.116,25.246,3.02483E-06,GAACG 842,asn,21,LYS,19.085,18.433,25.116,25.269,0.008624731,GAACG 842,asn,21,MET,19.085,17.467,25.116,25.291,9.64617E-06,GAACG 842,asn,21,PHE,19.085,19.008,25.116,25.279,1.18577E-05,GAACG 842,asn,21,PRO,19.085,nan,25.116,nan,5.91554E-07,GAACG 842,asn,21,SER,19.085,19,25.116,25.204,0.002266541,GAACG 842,asn,21,THR,19.085,19.024,25.116,25.214,0.000326762,GAACG 842,asn,21,TRP,19.085,-813.75,25.116,25.269,0,GAACG 842,asn,21,TYR,19.085,17.592,25.116,25.3,0.002398907,GAACG 842,asn,21,VAL,19.085,19.012,25.116,25.243,7.48668E-06,GAACG 844,leu,21,ALA,18.991,nan,25.449,23.307,2.04039E-05,ACTGG 844,leu,21,ARG,18.991,17.271,25.449,24.476,0.002374248,ACTGG 844,leu,21,ASN,18.991,17.9,25.449,23.959,0,ACTGG 844,leu,21,ASP,18.991,nan,25.449,23.484,0,ACTGG 844,leu,21,CYS,18.991,17.722,25.449,23.813,0,ACTGG 844,leu,21,GLN,18.991,18.045,25.449,24.181,0.013844436,ACTGG 844,leu,21,GLU,18.991,17.837,25.449,23.974,7.60062E-05,ACTGG 844,leu,21,GLY,18.991,nan,25.449,23.112,6.18599E-06,ACTGG 844,leu,21,HID,18.991,18.8,25.449,22.649,0.000420078,ACTGG 844,leu,21,HIE,18.991,18.743,25.449,22.631,0.000420078,ACTGG 844,leu,21,HIP,18.991,18.57,25.449,22.416,0.000420078,ACTGG 844,leu,21,ILE,18.991,nan,25.449,24.485,0.000693942,ACTGG 844,leu,21,LYS,18.991,18.01,25.449,24.586,0.000256634,ACTGG 844,leu,21,MET,18.991,18.879,25.449,24.854,0.010105387,ACTGG 844,leu,21,PHE,18.991,nan,25.449,23.783,0.000189452,ACTGG 844,leu,21,PRO,18.991,nan,25.449,nan,0.005231454,ACTGG 844,leu,21,SER,18.991,17.355,25.449,23.384,3.02498E-05,ACTGG 844,leu,21,THR,18.991,17.709,25.449,23.779,0.0001143,ACTGG 844,leu,21,TRP,18.991,19.019,25.449,-17.343,1.89782E-05,ACTGG 844,leu,21,TYR,18.991,nan,25.449,23.886,0,ACTGG 844,leu,21,VAL,18.991,nan,25.449,23.924,0.003086691,ACTGG 854,thr,21,ALA,19.006,18.868,25.428,24.879,0.002700254,CACAG 854,thr,21,ARG,19.006,nan,25.428,nan,0.004503796,CACAG 854,thr,21,ASN,19.006,19.085,25.428,21.074,0.00026171,CACAG 854,thr,21,ASP,19.006,18.771,25.428,22.568,0,CACAG 854,thr,21,CYS,19.006,19.012,25.428,25.233,0,CACAG 854,thr,21,GLN,19.006,nan,25.428,nan,4.62028E-05,CACAG 854,thr,21,GLU,19.006,nan,25.428,nan,7.44671E-05,CACAG 854,thr,21,GLY,19.006,18.769,25.428,24.564,3.01306E-05,CACAG 854,thr,21,HID,19.006,19.633,25.428,12.945,0,CACAG 854,thr,21,HIE,19.006,19.579,25.428,11.672,0,CACAG 854,thr,21,HIP,19.006,19.545,25.428,12.041,0,CACAG 854,thr,21,ILE,19.006,nan,25.428,25.71,0.007196829,CACAG 854,thr,21,LEU,19.006,nan,25.428,nan,0.000103822,CACAG 854,thr,21,LYS,19.006,nan,25.428,nan,0.015492198,CACAG 854,thr,21,MET,19.006,nan,25.428,nan,4.98897E-05,CACAG 854,thr,21,PHE,19.006,20.082,25.428,nan,0,CACAG 854,thr,21,PRO,19.006,nan,25.428,nan,0.001234416,CACAG 854,thr,21,SER,19.006,18.944,25.428,24.869,0.005746237,CACAG 854,thr,21,TRP,19.006,nan,25.428,nan,0,CACAG 854,thr,21,TYR,19.006,19.808,25.428,nan,0,CACAG 854,thr,21,VAL,19.006,nan,25.428,nan,4.85103E-05,CACAG 855,asp,21,ALA,19.019,18.546,25.223,25.055,0.000207324,AGATT 855,asp,21,ARG,19.019,19.519,25.223,25.205,4.25743E-05,AGATT 855,asp,21,ASN,19.019,18.929,25.223,25.082,0.008358349,AGATT 855,asp,21,CYS,19.019,18.812,25.223,25.242,0.000133767,AGATT 855,asp,21,GLN,19.019,19.193,25.223,25.18,3.4406E-05,AGATT 855,asp,21,GLU,19.019,19.166,25.223,24.939,0.00249586,AGATT 855,asp,21,GLY,19.019,18.422,25.223,24.937,0.001864223,AGATT 855,asp,21,HID,19.019,19.47,25.223,25.145,0.007242187,AGATT 855,asp,21,HIE,19.019,19.578,25.223,25.155,0.007242187,AGATT 855,asp,21,HIP,19.019,19.435,25.223,25.11,0.007242187,AGATT 855,asp,21,ILE,19.019,nan,25.223,nan,2.64712E-05,AGATT 855,asp,21,LEU,19.019,19.164,25.223,25.296,4.02325E-05,AGATT 855,asp,21,LYS,19.019,19.151,25.223,25.139,3.96179E-05,AGATT 855,asp,21,MET,19.019,19.472,25.223,25.493,0,AGATT 855,asp,21,PHE,19.019,19.62,25.223,25.208,6.4085E-05,AGATT 855,asp,21,PRO,19.019,nan,25.223,nan,7.4627E-06,AGATT 855,asp,21,SER,19.019,18.702,25.223,25.087,5.61774E-05,AGATT 855,asp,21,THR,19.019,18.761,25.223,25.107,4.27586E-06,AGATT 855,asp,21,TRP,19.019,20.546,25.223,25.553,0,AGATT 855,asp,21,TYR,19.019,19.724,25.223,25.236,0.016541687,AGATT 855,asp,21,VAL,19.019,nan,25.223,nan,0.002556222,AGATT