2021-04-04 2021-04-19 2021-05-10 2021-05-26 2021-06-07 2021-06-28 2021-07-19 2021-08-02 2021-08-09 2021-08-16 2021-08-23 2021-08-30 2021-09-01 2021-09-08 2021-09-13 2021-09-20 2021-10-04 2021-10-18 2021-10-26 2021-11-08 2021-11-15 2021-11-22 2021-11-29 2021-12-06 2021-12-27 2021-12-35 2022-01-03 2022-01-12 2022-01-18 2022-01-25 2022-01-31 2022-02-07 2022-02-28 2022-03-14 Covariant Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance A1214C(D405A) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) CAT1555-1557AAG(H519K) C1715A(T572N) 0.007 A1214G(D405G) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) CAT1555-1557AAG(H519K) C1715A(T572N) 0.006 A1217-1217del(406fs) 0.024 A1217-1217del(406fs) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.001 A1217-1217del(406fs) T1320A(N440K) 0.0015 A1217-1217del(406fs) T1355G(L452R) C1433A(T478K) 0.001 0.002 0.001 0.003 0.0006666666666666666 A1217-1217del(406fs) T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) 0.0006666666666666666 A1217-1217del(406fs) T1355G(L452R) C1433A(T478K) T1695C(F565F) 0.0005 A1217-1217del(406fs) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.001 A1217-1217del(406fs) T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0015 A1217-1217del(406fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0005 A1217-1217del(406fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0015 A1217C(E406A) G1251T(K417N) T1263C(Y421Y) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1649N(G550?) 0.002 0.002 A1217C(E406A) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1640A(T547K) 0.011 A1217G(E406G) G1251T(K417N) T1263C(Y421Y) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1649N(G550?) 0.005 0.002 A1217G(E406G) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.005 A1218T(E406D) A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.025 A1218T(E406D) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1596C(N532N) C1715A(T572N) 0.019 A1222-1222del(408fs) 0.009 A1222-1222del(408fs) T1320A(N440K) 0.0005 A1222-1222del(408fs) T1355G(L452R) C1433A(T478K) 0.00016666666666666666 0.001 A1222-1222del(408fs) T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) 0.0003333333333333333 A1222-1222del(408fs) T1355G(L452R) C1433A(T478K) T1695C(F565F) 0.00016666666666666666 A1222-1222del(408fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 A1224C(R408S) AAG1249-1251ATT(K417I) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.015 A1224C(R408S) C1230T(I410I) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.05 0.049 A1224C(R408S) C1244T(T415I) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.024 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1365A(L455L) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1738T(Q580*) 0.025 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1518C(Q506H) C1640A(T547K) 0.016 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1605G(K535K) C1640A(T547K) 0.025 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1640A(T547K) 0.013 0.025 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.001 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1717G(T573A) 0.023 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1676A(F559Y) 0.022 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) T1364C(L455S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.027 A1236C(P412P) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.003 A1236G(P412P) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.071 A1241G(Q414R) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.045 0.035666666666666666 A1241T(Q414L) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.024 A1242C(Q414H) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.01 A1242G(Q414Q) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.014 A1243C(T415P) T1355G(L452R) C1433A(T478K) 0.003 A1243G(T415A) T1355G(L452R) C1433A(T478K) 0.018 A1243G(T415A) T1355G(L452R) C1433A(T478K) T1545C(F515F) 0.042 A1250C(K417T) C1317A(N439K) CTT1321-1323CGC(L441R) AAG1330-1332AGT(K444S) T1334C(V445A) TAT1345-1347CGT(Y449R) T1355A(L452Q) A1358T(Y453F) T1364G(L455W) T1368G(F456L) T1380G(N460K) T1401C(D467D) G1430A(S477N) A1451T(E484V) TTT1456-1458CCT(F486P) T1469C(F490S) G1487T(G496V) CAA1492-1494TAC(Q498Y) C1495T(P499S) A1502C(N501T) G1511A(G504D) T1513C(Y505H) T1557A(H519Q) 0.011 A1250C(K417T) G1450A(E484K) A1501T(N501Y) 0.001 0.023 A1250C(K417T) G1450A(E484K) A1501T(N501Y) C1704T(D568D) 0.0255 A1259G(D420G) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.014 A1280G(D427G) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.037 A1283C(D428A) T1355G(L452R) C1433A(T478K) 0.0033333333333333335 A1283C(D428A) T1355G(L452R) C1433A(T478K) T1455C(G485G) 0.002 A1283G(D428G) T1355G(L452R) C1433A(T478K) C1435T(P479S) 0.0013333333333333333 A1283G(D428G) T1355G(L452R) C1433A(T478K) T1455A(G485G) 0.0029999999999999996 A1283G(D428G) T1355G(L452R) C1433A(T478K) T1455C(G485G) 0.0036666666666666666 A1288C(T430P) T1355G(L452R) C1433A(T478K) 0.005 A1288G(T430A) T1355G(L452R) C1433A(T478K) C1435T(P479S) 0.006333333333333333 A1288G(T430A) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.005666666666666667 A1290G(T430T) 0.007 A1290G(T430T) T1355G(L452R) C1433A(T478K) 0.006 A1290T(T430T) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0015 A1300G(I434V) T1389C(P463P) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.039 A1310C(N437T) T1355G(L452R) C1433A(T478K) 0.003 A1310G(N437S) T1355G(L452R) C1433A(T478K) 0.011 A1331C(K444T) A1432T(T478S) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.005 A1331C(K444T) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.041 0.008 A1331C(K444T) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1587A(K529K) C1715A(T572N) 0.006 A1331C(K444T) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.022 A1343G(N448S) G1423T(A475S) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 A1362G(R454R) C1425T(A475A) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.082 A1432T(T478S) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0055 A1451C(E484A) C1477A(Q493K) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0015 A1451C(E484A) T1456C(F486L) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.003 A1451C(E484A) T1456C(F486L) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0005 0.002 0.0015 A1451C(E484A) T1457C(F486S) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.031 0.002 A1451C(E484A) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.059 0.027 0.06 0.014 0.051 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1520A(P507Q) C1555A(H519N) C1715A(T572N) 0.007 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.202 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) CAT1555-1557AAG(H519K) C1715A(T572N) 0.003 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502G(N501S) C1555A(H519N) C1715A(T572N) 0.013 0.075 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.07350000000000001 0.148 0.024 0.088 0.008 0.057 0.072 0.063 0.112 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1574A(C525Y) C1592A(T531N) C1715A(T572N) 0.0325 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1587A(K529K) C1715A(T572N) 0.0055 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1596C(N532N) C1715A(T572N) 0.053 0.0455 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1596C(N532N) T1679G(L560R) C1715A(T572N) 0.011 A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1679G(L560R) C1715A(T572N) 0.009 A1451T(E484V) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.019 A1452C(E484D) 0.009 A1501T(N501Y) 0.004 0.009 0.0005 0.014 A1501T(N501Y) C1709A(A570D) 0.383 0.159 0.0185 0.085 A1501T(N501Y) C1709G(A570G) 0.074 A1501T(N501Y) G1558T(A520S) C1709A(A570D) 0.242 A1521C(P507P) 0.012 A1523C(Y508S) 0.011 A1525C(R509R) 0.017 A1548C(E516D) 0.028 A1595C(N532T) 0.014 A1595G(N532S) 0.015 A1595T(N532I) 0.007 C1221-1221del(407fs) 0.009 C1221-1221del(407fs) T1320A(N440K) 0.0005 C1221-1221del(407fs) T1355G(L452R) C1433A(T478K) 0.00016666666666666666 0.001 C1221-1221del(407fs) T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) 0.0003333333333333333 C1221-1221del(407fs) T1355G(L452R) C1433A(T478K) T1695C(F565F) 0.00016666666666666666 C1221-1221del(407fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 C1221T(V407V) A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1670G(K557R) 0.022 C1221T(V407V) T1355G(L452R) C1433A(T478K) 0.017 C1225T(Q409*) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.018 C1225T(Q409*) T1355G(L452R) C1433A(T478K) 0.021 C1230T(I410I) T1355G(L452R) C1433A(T478K) 0.012 C1240A(Q414K) A1243T(T415S) T1355G(L452R) C1433A(T478K) 0.013 C1240A(Q414K) T1355G(L452R) C1433A(T478K) 0.125 C1240A(Q414K) T1355G(L452R) C1433A(T478K) 1669-insertA(557fs) 0.024 C1240A(Q414K) T1355G(L452R) C1433A(T478K) T1722A(D574E) 0.013 C1240A(Q414K) T1355G(L452R) T1375C(S459P) C1433A(T478K) 0.035 C1244T(T415I) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.024 C1244T(T415I) T1355G(L452R) C1433A(T478K) G1642T(G548C) 0.009333333333333334 C1244T(T415I) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.009 C1276T(P426S) T1355G(L452R) C1433A(T478K) 0.016 0.025 C1289T(T430I) T1355G(L452R) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.014 C1296T(C432C) T1355G(L452R) C1433A(T478K) AT1482-1483del(494fs) 0.11533333333333333 C1296T(C432C) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.016 C1425T(A475A) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.004 0.049 C1425T(A475A) A1451T(E484V) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.076 C1433A(T478K) 0.0025 0.003 0.003 0.007 0.01 0.0011666666666666668 0.005 0.011 0.005 0.008 0.001 0.04 0.0006666666666666666 C1433A(T478K) C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0005 C1433A(T478K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 C1477A(Q493K) A1482G(S494S) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.058 C1477A(Q493K) C1492T(Q498*) C1555A(H519N) C1715A(T572N) 0.001 0.008 C1477A(Q493K) CAA1492-1494TAC(Q498Y) 0.001 C1477A(Q493K) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) 0.0008333333333333334 C1477A(Q493K) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.008499999999999999 C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1519A(P507T) C1555A(H519N) C1715A(T572N) 0.001 C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) A1669-1669del(557fs) C1715A(T572N) 0.004 C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1709A(A570D) C1715A(T572N) 0.003 C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.059 0.177 0.2505 0.242 0.275 0.178 0.065 0.021333333333333333 0.026 0.035 0.062 C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1679C(L560P) C1715A(T572N) 0.06 0.002 C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1715A(T572N) 0.0005 0.005 0.001 C1477A(Q493K) CAA1492-1494TAC(Q498Y) T1542G(S514S) C1555A(H519N) C1715A(T572N) 0.001 C1477A(Q493K) CAA1492-1494TAC(Q498Y) T1544G(F515C) C1555A(H519N) C1715A(T572N) 0.001 C1477A(Q493K) T1480C(S494P) C1492T(Q498*) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) 0.004 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1715A(T572N) 0.0003333333333333333 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502G(N501S) C1555A(H519N) C1715A(T572N) 0.0325 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1516A(Q506K) C1555A(H519N) 1675-insertT(559fs) C1715A(T572N) 0.003 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1524A(Y508*) C1555A(H519N) C1715A(T572N) 0.002 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) 1675-insertT(559fs) C1715A(T572N) 0.029 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) A1563C(P521P) C1715A(T572N) 0.024 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) A1585G(K529E) C1715A(T572N) 0.01 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) A1669-1669del(557fs) C1715A(T572N) 0.035 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1623T(F541F) C1715A(T572N) 0.045 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.114 0.073 0.3875 0.0015 0.068 0.099 0.072 0.104 0.04650000000000001 0.058 0.123 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) A1733G(D578G) 0.025 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1574A(C525Y) C1715A(T572N) 0.002 C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1651A(V551I) C1715A(T572N) 0.01 0.151 C1477A(Q493K) T1480C(S494P) T1490C(F497S) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1651A(V551I) C1715A(T572N) 0.012 C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.074 0.005 C1492A(Q498K) 0.008 C1497A(P499P) 0.009 C1515A(Y505*) 0.01 C1516A(Q506K) 0.012 C1519A(P507T) 0.012 C1520A(P507Q) 0.014 C1524A(Y508*) 0.123 C1549A(L517I) 0.007 C1559A(A520E) 0.013 C1562A(P521Q) 0.008 C1580A(P527H) 0.012 C1629A(F543L) 0.008 C1709A(A570D) 0.003 C1715A(T572N) 0.019 0.017 0.009 0.005 0.011 0.017 0.0018333333333333333 0.047 0.041 C1738A(Q580K) 0.008 C1738T(Q580*) 0.007 C1742A(T581K) 0.007 CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.004 0.002 0.012 G1216-1216del(406fs) 0.015 G1216-1216del(406fs) T1320A(N440K) 0.0015 G1216-1216del(406fs) T1355G(L452R) C1433A(T478K) 0.001 0.0006666666666666666 0.002 0.0013333333333333333 G1216-1216del(406fs) T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) 0.0005 G1216-1216del(406fs) T1355G(L452R) C1433A(T478K) T1695C(F565F) 0.0003333333333333333 G1216-1216del(406fs) T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0015 G1216-1216del(406fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0005 G1216-1216del(406fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.001 G1219-1219del(407fs) 0.008 G1219-1219del(407fs) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1219-1219del(407fs) T1355G(L452R) C1433A(T478K) 0.00016666666666666666 0.001 G1219-1219del(407fs) T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) 0.00016666666666666666 G1219-1219del(407fs) T1355G(L452R) C1433A(T478K) T1695C(F565F) 0.00016666666666666666 G1219-1219del(407fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 G1237A(G413R) A1451C(E484A) C1477A(Q493K) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.02 0.073 G1237A(G413R) T1355G(L452R) C1433A(T478K) 0.008333333333333333 G1237A(G413R) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.008333333333333333 G1238A(G413E) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.005 G1239T(G413G) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.007 G1239T(G413G) T1355G(L452R) C1433A(T478K) 0.032 0.059 G1239T(G413G) T1355G(L452R) C1433A(T478K) G1720A(D574N) 0.025 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1731A(R577R) 0.024 G1239T(G413G) T1355G(L452R) G1411A(E471K) C1433A(T478K) 0.021 G1247A(G416E) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0115 G1247A(G416E) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1596C(N532N) C1715A(T572N) 0.0125 G1251A(K417K) T1366-1366del(456fs) 0.13 G1251T(K417N) A1259G(D420G) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.006 G1251T(K417N) A1290C(T430T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 G1251T(K417N) A1290G(T430T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.022 G1251T(K417N) A1316C(N439T) T1320G(N440K) G1336A(G446S) A1402T(I468F) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.004 G1251T(K417N) A1316C(N439T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.004 G1251T(K417N) A1316G(N439S) T1320G(N440K) G1336A(G446S) A1402T(I468F) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 G1251T(K417N) A1316G(N439S) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.012 0.007 G1251T(K417N) C1256T(A419V) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.014 G1251T(K417N) C1256T(A419V) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1705G(I569V) 0.024 G1251T(K417N) C1289A(T430K) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) C1296T(C432C) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.019 0.017 G1251T(K417N) C1317T(N439N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.016 G1251T(K417N) G1255C(A419P) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 G1251T(K417N) G1295A(C432Y) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 G1251T(K417N) G1303A(A435T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) G1307-1307del(436fs) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1253C(I418T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) T1299C(V433V) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.013 G1251T(K417N) T1320G(N440K) A1325T(D442V) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.017 G1251T(K417N) T1320G(N440K) A1330C(K444Q) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1722A(D574E) 0.008 G1251T(K417N) T1320G(N440K) A1330G(K444E) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1722A(D574E) 0.013 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1343T(N448I) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.02 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1414C(I472L) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.007 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1414G(I472V) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.016 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1421G(Q474R) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.025 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1421T(Q474L) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) C1424T(A475V) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) C1433A(T478K) C1640A(T547K) 0.016 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1411A(E471K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.009 0.007 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1423T(A475S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.017 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1442T(N481I) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1459T(N487Y) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1460T(N487I) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.001 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) G1507-1507del(503fs) T1513C(Y505H) C1640A(T547K) 0.009 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) G1510T(G504C) T1513C(Y505H) C1640A(T547K) 0.002 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) G1511T(G504V) T1513C(Y505H) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1506C(G502G) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1512G(G504G) T1513C(Y505H) C1640A(T547K) 0.002 0.002 0.002 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513A(Y505N) C1516A(Q506K) C1640A(T547K) 0.008 0.015 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513A(Y505N) C1640A(T547K) 0.003 0.002 0.003 0.01 0.011 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) 1582-insertA(528fs) C1640A(T547K) 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1517C(Q506P) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1518C(Q506H) C1640A(T547K) 0.003 0.016 0.002 0.03 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1521C(P507P) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1525C(R509R) C1640A(T547K) 0.002 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) A1582G(K528E) C1640A(T547K) 0.026 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1640A(T547K) 0.002 0.019 0.022 0.081 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1519A(P507T) C1640A(T547K) 0.002 0.002 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1520A(P507Q) C1640A(T547K) 0.002 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1524A(Y508*) C1640A(T547K) 0.001 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1524T(Y508Y) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1559A(A520E) C1640A(T547K) 0.002 0.002 0.003 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1580T(P527L) C1640A(T547K) 0.026 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.72 0.752 0.838 0.724 0.848 0.797 0.781 0.782 0.408 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1669-1669del(557fs) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1672T(K558*) 0.017 0.014 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1692G(Q564Q) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1668T(N556N) 0.025 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1686T(F562F) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1715T(T572I) 0.004 0.023 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1724G(A575G) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1735T(P579S) 0.025 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) CCA1735-1737CTC(P579L) 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1702A(D568N) C1753T(L585F) 0.017 0.015 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1650A(G550G) 0.019 0.017 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1650C(G550G) 0.005 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1656A(L552L) A1721G(D574G) 0.017 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1659C(T553T) 0.015 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1659G(T553T) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1665C(S555S) 0.018 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1665G(S555S) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1675C(F559L) 0.01 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1675G(F559V) 0.013 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1676C(F559S) 0.012 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1676G(F559C) 0.012 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1677C(F559F) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1710C(A570A) 0.005 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1710G(A570A) 0.015 0.012 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1722C(D574D) 0.013 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1727C(V576A) 0.007 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1668T(N556N) 0.014 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) CAA1516-1518AAC(Q506N) C1640A(T547K) 0.001 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1526T(R509I) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1528T(V510L) C1640A(T547K) 0.007 0.002 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1576-1576del(526fs) C1640A(T547K) 0.009 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1599A(L533L) C1640A(T547K) 0.024 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1600A(V534I) C1640A(T547K) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1633A(G545S) C1640A(T547K) 0.012 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1634A(G545D) C1640A(T547K) 0.002 0.021 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1522G(Y508D) C1640A(T547K) 0.001 0.002 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1529G(V510G) C1640A(T547K) 0.002 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1532G(V511G) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1538C(L513P) C1640A(T547K) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1538G(L513R) C1640A(T547K) 0.001 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1539G(L513L) C1640A(T547K) 0.002 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1542G(S514S) C1640A(T547K) 0.001 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1543G(F515V) C1640A(T547K) 0.003 0.003 0.005 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1544G(F515C) C1640A(T547K) 0.002 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1551G(L517L) C1640A(T547K) 0.001 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1597G(L533V) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1616G(V539G) C1640A(T547K) 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1622G(F541C) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) TAC1513-1515CAA(Y505Q) C1640A(T547K) 0.001 0.004 0.003 0.009 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493T(Q498L) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) T1455G(G485G) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) T1448C(V483A) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1614G(C538W) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) GA1393-1394del(465fs) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.011 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1341C(G447G) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1355C(L452P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1359A(Y453*) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.011 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1359C(Y453Y) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1389C(P463P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.009 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) 0.572 G1251T(K417N) T1320G(N440K) GGT1336-1338ATT(G446I) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) T1320G(N440K) T1322C(L441P) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) T1323C(L441L) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 0.024 G1297-1297del(433fs) T1355G(L452R) C1433A(T478K) A1451C(E484A) T1675-1675del(559fs) 0.006 G1297-1297del(433fs) T1355G(L452R) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 G1336A(G446S) T1366C(F456L) T1380G(N460K) GAA1450-1452ACA(E484T) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.057 G1339A(G447S) T1355G(L452R) C1433A(T478K) C1435T(P479S) 0.009333333333333334 G1339A(G447S) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.009333333333333334 G1339T(G447C) T1355G(L452R) C1433A(T478K) 0.002 G1340A(G447D) C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.006 G1340A(G447D) C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) TTCAATGG1627-1634del(543fs) C1715A(T572N) 0.055 G1365T(L455F) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 G1423T(A475S) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0016666666666666668 G1423T(A475S) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.002 G1430A(S477N) 0.04 0.163 G1430A(S477N) A1604C(K535T) C1718T(T573I) 0.075 G1430A(S477N) C1718T(T573I) 0.009 G1430A(S477N) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.012 0.043 G1445A(G482D) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.063 G1447T(V483F) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 G1450A(E484K) 0.078 0.034 0.032 G1450A(E484K) A1501T(N501Y) 0.034 0.005 G1450A(E484K) T1725C(A575A) 0.083 G1526T(R509I) 0.01 G1534T(V512L) 0.012 G1546T(E516*) 0.015 G1643T(G548V) 0.1 T1215-1215del(405fs) 0.009 T1215-1215del(405fs) T1320A(N440K) 0.001 T1215-1215del(405fs) T1355G(L452R) C1433A(T478K) 0.0005 0.002 0.0003333333333333333 T1215-1215del(405fs) T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) 0.0003333333333333333 T1215-1215del(405fs) T1355G(L452R) C1433A(T478K) T1695C(F565F) 0.0003333333333333333 T1215-1215del(405fs) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 T1253C(I418T) T1355G(L452R) C1433A(T478K) 0.021 T1274C(L425S) T1410G(T470T) 0.001 T1274C(L425S) T1410G(T470T) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1497A(P499P) C1555A(H519N) C1715A(T572N) 0.001 T1274C(L425S) T1410G(T470T) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1516A(Q506K) C1555A(H519N) C1715A(T572N) 0.005 T1274C(L425S) T1410G(T470T) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1524A(Y508*) C1555A(H519N) C1715A(T572N) 0.016 T1274C(L425S) T1410G(T470T) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.329 T1274C(L425S) T1410G(T470T) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1715A(T572N) 0.006 T1320A(N440K) 0.087 0.46 0.209 T1320A(N440K) A1501T(N501Y) 0.0005 T1320A(N440K) A1525C(R509R) 0.001 T1320A(N440K) A1548C(E516D) 0.0015 T1320A(N440K) A1609T(K537*) 0.0035 T1320A(N440K) A1733C(D578A) 0.0005 T1320A(N440K) C1516A(Q506K) 0.001 T1320A(N440K) C1519A(P507T) 0.001 T1320A(N440K) C1520A(P507Q) 0.001 T1320A(N440K) C1524A(Y508*) 0.0025 T1320A(N440K) C1559A(A520E) 0.0015 T1320A(N440K) C1565A(A522E) 0.0005 T1320A(N440K) C1629A(F543L) 0.0005 T1320A(N440K) C1644A(G548G) 0.0005 T1320A(N440K) C1668A(N556K) 0.002 T1320A(N440K) G1423T(A475S) 0.0025 T1320A(N440K) G1534T(V512L) 0.0005 T1320A(N440K) T1512G(G504G) 0.001 T1320A(N440K) T1513G(Y505D) 0.0005 T1320A(N440K) T1545G(F515L) 0.0005 T1320A(N440K) T1656G(L552L) 0.0005 T1320A(N440K) T1693G(F565V) 0.0005 T1320A(N440K) T1694G(F565C) 0.0005 T1320A(N440K) T1722C(D574D) 0.001 T1320A(N440K) T1751-1751del(584fs) 0.0005 T1320A(N440K) T1754-1754del(585fs) 0.001 T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.473 T1334-1334del(445fs) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.008 T1335G(V445V) G1430A(S477N) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.002 T1341C(G447G) T1355G(L452R) C1433A(T478K) 0.203 T1355G(L452R) 0.034 0.002 0.018 0.002 T1355G(L452R) A1407G(S469S) C1433A(T478K) 0.309 T1355G(L452R) A1407G(S469S) C1433A(T478K) C1524A(Y508*) 0.003 T1355G(L452R) A1408C(T470P) C1433A(T478K) 0.001 T1355G(L452R) A1413C(E471D) C1433A(T478K) 0.006 T1355G(L452R) A1413G(E471E) C1433A(T478K) 0.011 T1355G(L452R) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1355G(L452R) C1424A(A475D) C1433A(T478K) 0.001 T1355G(L452R) C1431T(S477S) C1433A(T478K) 0.009833333333333333 T1355G(L452R) C1433-1433del(478fs) A1459T(N487Y) T1734C(D578D) 0.0006666666666666666 T1355G(L452R) C1433-1433del(478fs) T1734C(D578D) 0.11599999999999999 T1355G(L452R) C1433A(T478K) 0.258 0.176 0.071 0.387 0.448 0.632 0.303 0.826 0.396 0.188 0.093 0.054 0.257 0.586 0.394 0.7806666666666667 0.6466666666666666 0.012 0.088 0.263 0.034 T1355G(L452R) C1433A(T478K) 1473-insertT(491fs) 0.027 T1355G(L452R) C1433A(T478K) A1451C(E484A) 0.001 T1355G(L452R) C1433A(T478K) A1451C(E484A) T1693-1693del(565fs) 0.001 T1355G(L452R) C1433A(T478K) A1451T(E484V) T1693-1693del(565fs) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) A1452C(E484D) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) A1452C(E484D) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) A1514C(Y505S) 0.001 T1355G(L452R) C1433A(T478K) A1514C(Y505S) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) A1518C(Q506H) T1693-1693del(565fs) 0.0005 T1355G(L452R) C1433A(T478K) A1525C(R509R) 0.002 0.0006666666666666666 0.002 T1355G(L452R) C1433A(T478K) A1525C(R509R) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) A1527C(R509S) 0.00016666666666666666 0.002 T1355G(L452R) C1433A(T478K) A1527C(R509S) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) A1527G(R509R) 0.0005 0.004 0.001 T1355G(L452R) C1433A(T478K) A1527G(R509R) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) A1527G(R509R) T1695C(F565F) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) A1527T(R509S) 0.001 T1355G(L452R) C1433A(T478K) A1548C(E516D) 0.0003333333333333333 0.0003333333333333333 T1355G(L452R) C1433A(T478K) A1548C(E516D) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) A1554C(L518L) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) A1609T(K537*) T1653A(V551V) 0.004 0.0006666666666666666 T1355G(L452R) C1433A(T478K) A1619G(N540S) 0.016 T1355G(L452R) C1433A(T478K) A1661G(E554G) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) A1669-1669del(557fs) 0.011000000000000001 T1355G(L452R) C1433A(T478K) AT1482-1483del(494fs) 0.002 T1355G(L452R) C1433A(T478K) C1435T(P479S) 0.030333333333333334 T1355G(L452R) C1433A(T478K) C1436T(P479L) 0.368 T1355G(L452R) C1433A(T478K) C1467T(Y489Y) 0.013 T1355G(L452R) C1433A(T478K) C1477A(Q493K) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0005 T1355G(L452R) C1433A(T478K) C1477A(Q493K) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) C1496T(P499L) 0.017666666666666667 T1355G(L452R) C1433A(T478K) C1497A(P499P) 0.003 T1355G(L452R) C1433A(T478K) C1497T(P499P) 0.016 T1355G(L452R) C1433A(T478K) C1515A(Y505*) 0.002 T1355G(L452R) C1433A(T478K) C1515A(Y505*) T1693-1693del(565fs) 0.0013333333333333333 T1355G(L452R) C1433A(T478K) C1516A(Q506K) 0.001 0.002 0.00016666666666666666 0.009 T1355G(L452R) C1433A(T478K) C1516A(Q506K) T1693-1693del(565fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) C1519A(P507T) 0.003 T1355G(L452R) C1433A(T478K) C1519A(P507T) T1693-1693del(565fs) 0.0031666666666666666 T1355G(L452R) C1433A(T478K) C1520A(P507Q) 0.0005 0.007 0.0003333333333333333 0.0003333333333333333 T1355G(L452R) C1433A(T478K) C1520A(P507Q) T1693-1693del(565fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) C1520A(P507Q) T1695C(F565F) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) C1524A(Y508*) 0.002 0.002 0.002 0.0013333333333333333 0.017 0.0015 0.003 0.0023333333333333335 0.0033333333333333335 T1355G(L452R) C1433A(T478K) C1524A(Y508*) T1693-1693del(565fs) 0.0005 T1355G(L452R) C1433A(T478K) C1524A(Y508*) T1695C(F565F) 0.001 T1355G(L452R) C1433A(T478K) C1524A(Y508*) T1722C(D574D) 0.0016666666666666668 T1355G(L452R) C1433A(T478K) C1537A(L513I) 0.003 T1355G(L452R) C1433A(T478K) C1541T(S514F) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) C1549A(L517I) 0.002 T1355G(L452R) C1433A(T478K) C1559A(A520E) 0.0008333333333333334 0.005 0.002 0.0003333333333333333 T1355G(L452R) C1433A(T478K) C1559A(A520E) T1693-1693del(565fs) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) C1559A(A520E) T1695C(F565F) 0.0008333333333333334 T1355G(L452R) C1433A(T478K) C1561A(P521T) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) C1561A(P521T) T1693-1693del(565fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) C1565A(A522E) 0.001 T1355G(L452R) C1433A(T478K) C1565A(A522E) T1693-1693del(565fs) 0.0008333333333333334 T1355G(L452R) C1433A(T478K) C1565T(A522V) 0.038 T1355G(L452R) C1433A(T478K) C1565T(A522V) A1692G(Q564Q) 0.007 T1355G(L452R) C1433A(T478K) C1565T(A522V) C1715A(T572N) 0.003 T1355G(L452R) C1433A(T478K) C1579A(P527T) T1693-1693del(565fs) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) C1617A(V539V) 0.027 T1355G(L452R) C1433A(T478K) C1617A(V539V) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) C1629A(F543L) T1693-1693del(565fs) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) C1629T(F543F) 0.002 T1355G(L452R) C1433A(T478K) C1629T(F543F) A1737G(P579P) 0.0795 T1355G(L452R) C1433A(T478K) C1640T(T547I) 0.039 T1355G(L452R) C1433A(T478K) C1644A(G548G) T1693-1693del(565fs) 0.001 T1355G(L452R) C1433A(T478K) C1686T(F562F) 0.037 T1355G(L452R) C1433A(T478K) C1687A(Q563K) 0.003 0.0005 T1355G(L452R) C1433A(T478K) C1715A(T572N) 0.008 0.013 T1355G(L452R) C1433A(T478K) C1742A(T581K) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.002 T1355G(L452R) C1433A(T478K) G1439A(C480Y) A1451C(E484A) T1693-1693del(565fs) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) G1439C(C480S) A1451C(E484A) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1445A(G482D) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1445T(G482V) T1693-1693del(565fs) 0.001 T1355G(L452R) C1433A(T478K) G1447T(V483F) 0.001 0.00016666666666666666 0.001 T1355G(L452R) C1433A(T478K) G1450T(E484*) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1453C(G485R) 0.058 T1355G(L452R) C1433A(T478K) G1463T(C488F) 0.005 T1355G(L452R) C1433A(T478K) G1505T(G502V) 0.002 T1355G(L452R) C1433A(T478K) G1507T(V503F) 0.0008333333333333334 0.004 T1355G(L452R) C1433A(T478K) G1507T(V503F) T1695C(F565F) 0.0008333333333333334 T1355G(L452R) C1433A(T478K) G1511T(G504V) 0.003 T1355G(L452R) C1433A(T478K) G1526T(R509I) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1526T(R509I) T1695C(F565F) 0.0005 T1355G(L452R) C1433A(T478K) G1528A(V510I) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1528A(V510I) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1528T(V510L) 0.0005 0.001 T1355G(L452R) C1433A(T478K) G1528T(V510L) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1528T(V510L) T1695C(F565F) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) G1531T(V511L) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1531T(V511L) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1534T(V512L) 0.0005 T1355G(L452R) C1433A(T478K) G1534T(V512L) T1695C(F565F) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) G1546A(E516K) T1693-1693del(565fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1546T(E516*) 0.0005 0.002 T1355G(L452R) C1433A(T478K) G1546T(E516*) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1558T(A520S) 0.0005 T1355G(L452R) C1433A(T478K) G1558T(A520S) T1695C(F565F) 0.0005 T1355G(L452R) C1433A(T478K) G1564T(A522S) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1564T(A522S) T1695C(F565F) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1570T(V524F) T1695C(F565F) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1576T(G526*) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1576T(G526*) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1576T(G526*) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1577A(G526E) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) G1642A(G548S) 0.002 0.0003333333333333333 T1355G(L452R) C1433A(T478K) G1642T(G548C) 0.030666666666666665 T1355G(L452R) C1433A(T478K) G1651T(V551F) 0.036 T1355G(L452R) C1433A(T478K) G1732C(D578H) 0.039 T1355G(L452R) C1433A(T478K) T1448A(V483D) 0.005 T1355G(L452R) C1433A(T478K) T1448C(V483A) 0.003 T1355G(L452R) C1433A(T478K) T1455A(G485G) 0.0016666666666666668 T1355G(L452R) C1433A(T478K) T1455G(G485G) 0.0030000000000000005 T1355G(L452R) C1433A(T478K) T1506C(G502G) 0.038 T1355G(L452R) C1433A(T478K) T1508-1508del(503fs) 0.026 T1355G(L452R) C1433A(T478K) T1512A(G504G) 0.0003333333333333333 0.001 T1355G(L452R) C1433A(T478K) T1512A(G504G) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1512G(G504G) 0.002 0.0025 0.008 0.002 0.0006666666666666666 0.0006666666666666666 T1355G(L452R) C1433A(T478K) T1512G(G504G) T1693-1693del(565fs) 0.0005 T1355G(L452R) C1433A(T478K) T1512G(G504G) T1695C(F565F) 0.0021666666666666666 T1355G(L452R) C1433A(T478K) T1513A(Y505N) 0.001 T1355G(L452R) C1433A(T478K) T1513A(Y505N) T1695C(F565F) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) T1513G(Y505D) 0.001 0.0011666666666666668 0.004 0.001 0.0006666666666666666 0.001 T1355G(L452R) C1433A(T478K) T1513G(Y505D) T1695C(F565F) 0.0008333333333333334 T1355G(L452R) C1433A(T478K) T1522G(Y508D) 0.0005 0.002 T1355G(L452R) C1433A(T478K) T1522G(Y508D) T1695C(F565F) 0.0005 T1355G(L452R) C1433A(T478K) T1529A(V510E) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) T1529A(V510E) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1529G(V510G) 0.0008333333333333334 0.002 T1355G(L452R) C1433A(T478K) T1529G(V510G) T1695C(F565F) 0.0008333333333333334 T1355G(L452R) C1433A(T478K) T1532G(V511G) 0.0003333333333333333 0.001 T1355G(L452R) C1433A(T478K) T1532G(V511G) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1535G(V512G) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) T1538G(L513R) 0.0003333333333333333 0.001 T1355G(L452R) C1433A(T478K) T1538G(L513R) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1539G(L513L) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1539G(L513L) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1540G(S514A) 0.001 0.0006666666666666666 0.003 0.0006666666666666666 T1355G(L452R) C1433A(T478K) T1540G(S514A) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1543G(F515V) 0.0008333333333333334 0.004 0.0003333333333333333 0.001 T1355G(L452R) C1433A(T478K) T1543G(F515V) T1695C(F565F) 0.0005 T1355G(L452R) C1433A(T478K) T1544G(F515C) 0.00016666666666666666 0.002 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1544G(F515C) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) T1544G(F515C) T1695C(F565F) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) T1545G(F515L) 0.001 0.0006666666666666666 0.002 0.001 T1355G(L452R) C1433A(T478K) T1545G(F515L) T1695C(F565F) 0.0005 T1355G(L452R) C1433A(T478K) T1550G(L517R) 0.0003333333333333333 0.001 T1355G(L452R) C1433A(T478K) T1550G(L517R) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1551G(L517L) 0.0003333333333333333 0.001 T1355G(L452R) C1433A(T478K) T1551G(L517L) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1553G(L518R) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1553G(L518R) T1695C(F565F) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1557G(H519Q) 0.0005 0.004 0.001 0.0006666666666666666 T1355G(L452R) C1433A(T478K) T1557G(H519Q) T1695C(F565F) 0.0005 T1355G(L452R) C1433A(T478K) T1572G(V524V) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) T1622G(F541C) T1693-1693del(565fs) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) T1627C(F543L) 0.0014999999999999998 T1355G(L452R) C1433A(T478K) T1627G(F543V) 0.0011666666666666668 0.007 T1355G(L452R) C1433A(T478K) T1650G(G550G) T1693-1693del(565fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1663C(S555P) 0.016 T1355G(L452R) C1433A(T478K) T1665G(S555S) T1693-1693del(565fs) 0.0013333333333333333 T1355G(L452R) C1433A(T478K) T1679G(L560R) T1693-1693del(565fs) 0.0011666666666666668 T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) 0.14116666666666666 T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) G1756-1756del(586fs) 0.00016666666666666666 T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) T1751-1751del(584fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1693-1693del(565fs) T1754-1754del(585fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1693G(F565V) 0.001 0.0006666666666666666 T1355G(L452R) C1433A(T478K) T1694G(F565C) 0.0003333333333333333 0.001 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1695C(F565F) 0.145 T1355G(L452R) C1433A(T478K) T1695C(F565F) T1751-1751del(584fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1695C(F565F) T1754-1754del(585fs) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) T1706G(I569S) 0.019 T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.023 0.00016666666666666666 0.057999999999999996 0.0016666666666666668 0.237 T1355G(L452R) C1433A(T478K) T1734C(D578D) 0.015666666666666666 T1355G(L452R) C1433A(T478K) T1751-1751del(584fs) 0.00016666666666666666 0.001 T1355G(L452R) C1433A(T478K) T1754-1754del(585fs) 0.001 0.0005 0.002 T1355G(L452R) C1433A(T478K) TTT1693-1695TGC(F565C) 0.00016666666666666666 T1355G(L452R) C1433G(T478R) T1693-1693del(565fs) 0.0005 T1355G(L452R) C1433T(T478I) T1693-1693del(565fs) 0.00016666666666666666 T1355G(L452R) G1374A(K458K) C1433A(T478K) 0.085 T1355G(L452R) G1395T(E465D) C1433A(T478K) 0.003 T1355G(L452R) G1423T(A475S) C1433A(T478K) 0.005 0.001 T1355G(L452R) G1430T(S477I) C1433A(T478K) 0.023 T1355G(L452R) GAA1450-1452ACA(E484T) TTT1456-1458CCT(F486P) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1355G(L452R) T1389-1389del(463fs) C1433A(T478K) 0.008 0.010333333333333333 T1355G(L452R) T1389C(P463P) C1433A(T478K) 0.032 0.003 T1355G(L452R) T1404A(I468I) C1433A(T478K) 0.002 0.0003333333333333333 T1355G(L452R) T1419C(Y473Y) C1433A(T478K) 0.095 T1355G(L452R) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1715A(T572N) 0.0008333333333333334 T1355G(L452R) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.001 T1355G(L452R) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0235 T1355G(L452R) T1693-1693del(565fs) 0.0008333333333333334 T1363A(L455M) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.085 T1366C(F456L) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.11 0.086 0.013 0.058 T1366C(F456L) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1653A(V551V) C1715A(T572N) 0.019 T1366C(F456L) T1380G(N460K) GAA1450-1452ACA(E484T) TTT1456-1458CCT(F486P) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.016666666666666666 T1366C(F456L) T1380G(N460K) GAA1450-1452ACA(E484T) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.03 0.087 T1375C(S459P) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1651A(V551I) C1715A(T572N) 0.021 T1380A(N460K) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.059 T1380G(N460K) A1451C(E484A) T1456C(F486L) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0045 T1380G(N460K) A1451C(E484A) T1456C(F486L) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) A1451C(E484A) T1456C(F486L) T1480C(S494P) CAA1492-1494TAC(Q498Y) CAT1555-1557AAG(H519K) C1715A(T572N) 0.002 T1380G(N460K) A1451C(E484A) T1457C(F486S) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0015 T1380G(N460K) A1451C(E484A) T1457C(F486S) T1480C(S494P) CAA1492-1494TAC(Q498Y) CAT1555-1557AAG(H519K) C1715A(T572N) 0.002 T1380G(N460K) A1451C(E484A) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1468C(F490L) C1471G(P491A) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.029 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) C1492T(Q498*) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) C1492T(Q498*) CAT1555-1557AAG(H519K) C1715A(T572N) 0.003 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1517C(Q506P) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1548C(E516D) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1626A(N542K) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.267 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) T1754-1754del(585fs) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) CAT1555-1557AAG(H519K) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1513G(Y505D) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1539G(L513L) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1540G(S514A) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1543G(F515V) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1545G(F515L) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1550G(L517R) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1518C(Q506H) CAT1555-1557AAG(H519K) C1715A(T572N) 0.002 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.046 0.038 0.042 0.011333333333333334 0.106 0.066 0.074 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1598C(L533S) C1715A(T572N) 0.024 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1715A(T572N) 0.002 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) CAT1555-1557AAG(H519K) C1715A(T572N) 0.201 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) CAT1555-1557AAG(H519K) T1652A(V551D) C1715A(T572N) 0.017 T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) T1543G(F515V) CAT1555-1557AAG(H519K) C1715A(T572N) 0.005 T1380G(N460K) A1451T(E484V) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1380G(N460K) A1451T(E484V) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.032 0.011 0.071 T1380G(N460K) C1383A(L461L) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.039 T1380G(N460K) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) T1500C(T500T) C1555A(H519N) G1651A(V551I) C1715A(T572N) 0.012 T1380G(N460K) G1411A(E471K) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) G1651A(V551I) C1715A(T572N) 0.01 T1380G(N460K) G1444T(G482C) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0025 T1380G(N460K) G1445T(G482V) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0006666666666666666 T1380G(N460K) GAA1450-1452ACA(E484T) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.011 T1380G(N460K) T1410A(T470T) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.002 T1380G(N460K) T1410G(T470T) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1514C(Y505S) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1518C(Q506H) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1515A(Y505*) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0015 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1516A(Q506K) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1519A(P507T) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0055 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1520A(P507Q) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.003 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1524A(Y508*) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.004 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1537A(L513I) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) G1546A(E516K) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1513A(Y505N) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1542G(S514S) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.001 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1544A(F515Y) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1544G(F515C) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0025 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.1845 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1497A(P499P) A1502C(N501T) T1550-1550del(517fs) C1555A(H519N) C1715A(T572N) 0.0005 T1380G(N460K) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.04466666666666667 T1380G(N460K) T1469A(F490Y) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.001 T1389C(P463P) C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.007 T1389C(P463P) C1477A(Q493K) TCA1480-1482CGA(S494R) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.013 T1404A(I468I) T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0006666666666666666 T1410C(T470T) A1451C(E484A) T1456C(F486L) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.002 T1410C(T470T) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.111 T1410C(T470T) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1627C(F543L) C1715A(T572N) 0.011 T1410C(T470T) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1627G(F543V) C1715A(T572N) 0.01 T1410C(T470T) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.02 T1456C(F486L) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.025 T1469A(F490Y) C1477A(Q493K) CAA1492-1494TAC(Q498Y) C1715A(T572N) 0.1215 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) C1492T(Q498*) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.0005 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) C1492T(Q498*) C1555A(H519N) C1715A(T572N) 0.0035 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1523C(Y508S) C1555A(H519N) C1715A(T572N) 0.0005 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1525C(R509R) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1515A(Y505*) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1516A(Q506K) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1520A(P507Q) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1524A(Y508*) C1555A(H519N) C1715A(T572N) 0.0005 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) A1609T(K537*) C1715A(T572N) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) A1609T(K537*) T1653A(V551V) C1715A(T572N) 0.001 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1687A(Q563K) C1715A(T572N) 0.0008333333333333334 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.073 0.123 0.15666666666666668 0.134 0.106 0.108 0.082 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) C1753-1753del(585fs) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) T1751-1751del(584fs) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) T1754-1754del(585fs) 0.0003333333333333333 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) G1642A(G548S) C1715A(T572N) 0.0006666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) T1601C(V534A) C1715A(T572N) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) T1627C(F543L) C1715A(T572N) 0.0021666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) T1627G(F543V) C1715A(T572N) 0.002 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1715A(T572N) 0.0008333333333333334 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) CAT1555-1557AAG(H519K) C1715A(T572N) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1512G(G504G) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1513G(Y505D) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1540G(S514A) C1555A(H519N) C1715A(T572N) 0.0005 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1543G(F515V) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1545G(F515L) C1555A(H519N) C1715A(T572N) 0.0003333333333333333 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1518C(Q506H) C1555A(H519N) C1715A(T572N) 0.005 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1497A(P499P) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.00016666666666666666 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1516A(Q506K) C1555A(H519N) C1715A(T572N) 0.006 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1520A(P507Q) C1555A(H519N) C1715A(T572N) 0.0015 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1524A(Y508*) C1555A(H519N) C1715A(T572N) 0.002 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) A1609T(K537*) C1715A(T572N) 0.003 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1668A(N556K) C1715A(T572N) 0.0015 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1709A(A570D) C1715A(T572N) 0.001 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0595 0.067 0.234 0.147 0.155 0.008 0.026 0.028 0.003 0.01 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) T1569C(T523T) C1715A(T572N) 0.049 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) T1543G(F515V) C1555A(H519N) C1715A(T572N) 0.005 T1480C(S494P) 0.169 T1480C(S494P) C1715A(T572N) 0.005 T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.0035 0.012 0.006 T1480C(S494P) CAA1492-1494TAC(Q498Y) C1715A(T572N) 0.0025 T1512A(G504G) 0.017 T1512G(G504G) 0.049 T1513A(Y505N) 0.01 T1513G(Y505D) 0.028 T1522G(Y508D) 0.017 T1529G(V510G) 0.008 T1532G(V511G) 0.012 T1538G(L513R) 0.015 T1539G(L513L) 0.015 T1540G(S514A) 0.024 T1543G(F515V) 0.016 T1544G(F515C) 0.01 T1545G(F515L) 0.021 T1550G(L517R) 0.01 T1551G(L517L) 0.009 T1557G(H519Q) 0.014 T1588A(S530T) 0.106 T1588C(S530P) 0.011 T1588G(S530A) 0.059 TTT1468-1470CAT(F490H) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) C1715A(T572N) 0.01