2021-02-06 2021-04-04 2021-04-19 2021-05-10 2021-06-14 2021-06-28 2021-07-19 2021-08-02 2021-08-09 2021-08-16 2021-08-23 2021-08-30 2021-09-01 2021-09-08 2021-09-13 2021-09-20 2021-10-04 2021-10-18 2021-10-26 2021-11-08 2021-11-15 2021-11-22 2021-11-29 2021-12-13 2021-12-27 2021-12-36 2022-01-03 2022-01-12 2022-01-18 2022-01-25 2022-01-31 2022-02-07 2022-02-23 2022-02-28 Covariant Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance Abundance A1214C(D405A) T1355G(L452R) C1433A(T478K) 0.004 A1214G(D405G) T1355G(L452R) C1433A(T478K) 0.016 A1217-1217del(406fs) 0.002 A1217-1217del(406fs) A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.0015 A1217-1217del(406fs) A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.001 A1217-1217del(406fs) A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.003 A1217-1217del(406fs) A1501T(N501Y) C1709A(A570D) 0.004 A1217-1217del(406fs) G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) 0.0015 A1217-1217del(406fs) G1239T(G413G) T1355G(L452R) C1433A(T478K) 0.002 A1217-1217del(406fs) G1450A(E484K) 0.0005 A1217-1217del(406fs) T1355G(L452R) C1433A(T478K) 0.002 0.002 0.0014 0.004 0.003 0.002 0.002 A1217-1217del(406fs) T1355G(L452R) C1433A(T478K) T1542C(S514S) 0.004 A1217C(E406A) G1251T(K417N) T1263C(Y421Y) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1649N(G550?) 0.003 A1217C(E406A) G1251T(K417N) T1263C(Y421Y) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1649N(G550?) 0.003 A1217C(E406A) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1640A(T547K) 0.009 A1217G(E406G) G1251T(K417N) T1263C(Y421Y) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1649N(G550?) 0.004 A1217G(E406G) G1251T(K417N) T1263C(Y421Y) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1649N(G550?) 0.006 A1217G(E406G) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 A1218T(E406D) A1501T(N501Y) C1709A(A570D) 0.026 A1222-1222del(408fs) A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.0005 A1222-1222del(408fs) A1501T(N501Y) C1709A(A570D) 0.001 A1222-1222del(408fs) T1355G(L452R) C1433A(T478K) 0.001 0.0003333333333333333 A1224C(R408S) AAG1249-1251ATT(K417I) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.011 A1224C(R408S) C1230T(I410I) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.035 A1224C(R408S) C1230T(I410I) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) T1448C(V483A) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.052 A1224C(R408S) G1251T(K417N) C1313T(S438F) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.101 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1365A(L455L) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1738T(Q580*) 0.024 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) ACA1432-1434AAAAinsert(T478Kfsinsert) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.064 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1605G(K535K) C1640A(T547K) 0.017 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.029 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1717G(T573A) 0.015 A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) T1364C(L455S) G1430A(S477N) C1433A(T478K) T1448C(V483A) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.026 A1241T(Q414L) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1552T(L518L) C1640A(T547K) 0.025 A1242G(Q414Q) G1251T(K417N) T1257C(A419A) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.015 A1243C(T415P) T1355G(L452R) C1433A(T478K) G1504T(G502C) 0.005 A1243G(T415A) T1355G(L452R) C1433A(T478K) T1542C(S514S) 0.02 A1243T(T415S) T1355G(L452R) C1433A(T478K) G1504T(G502C) 0.025 A1250C(K417T) 0.008 A1250C(K417T) A1318G(N440D) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) T1480C(S494P) CAA1492-1494TAC(Q498Y) 0.002 A1250C(K417T) A1318G(N440D) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) 0.002 A1250C(K417T) A1331C(K444T) A1346C(Y449S) T1389-1389del(463fs) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.085 A1250C(K417T) A1331C(K444T) A1434C(T478T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.0005 A1250C(K417T) A1331C(K444T) A1451C(E484A) 0.018 A1250C(K417T) A1331C(K444T) A1451C(E484A) A1494C(Q498H) 0.0035 0.013 A1250C(K417T) A1331C(K444T) A1451C(E484A) A1494C(Q498H) A1712G(D571G) 0.007 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.159 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1518C(Q506H) A1712G(D571G) 0.0005 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.447 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) T1722C(D574D) 0.0005 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) T1751-1751del(584fs) 0.0005 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) T1754-1754del(585fs) 0.001 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1516A(Q506K) T1550A(L517H) A1712G(D571G) 0.007 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1520A(P507Q) A1712G(D571G) 0.001 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1524A(Y508*) A1712G(D571G) 0.0025 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1565A(A522E) A1712G(D571G) 0.001 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1709A(A570D) A1712G(D571G) 0.001 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1513G(Y505D) A1712G(D571G) 0.0005 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1543G(F515V) A1712G(D571G) 0.0005 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1550A(L517H) A1712G(D571G) 0.005 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1627G(F543V) A1712G(D571G) 0.0005 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1693G(F565V) A1712G(D571G) 0.001 A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1694G(F565C) A1712G(D571G) 0.001 A1250C(K417T) A1331C(K444T) G1430T(S477I) A1432T(T478S) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.007 A1250C(K417T) A1331C(K444T) G1430T(S477I) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.057 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) A1459T(N487Y) T1469A(F490Y) A1494C(Q498H) 0.001 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) A1494C(Q498H) 0.014 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) C1467T(Y489Y) T1469A(F490Y) A1494C(Q498H) 0.059 0.227 0.015333333333333332 0.002 0.081 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) C1467T(Y489Y) T1469A(F490Y) A1494C(Q498H) C1516A(Q506K) 0.004 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) C1467T(Y489Y) T1469A(F490Y) A1494C(Q498H) T1550A(L517H) 0.0085 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0045 0.421 0.031 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1515A(Y505*) 0.004 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1516A(Q506K) 0.004 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1524A(Y508*) 0.003 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1559A(A520E) 0.005 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1538G(L513R) 0.001 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1539G(L513L) 0.005 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1543G(F515V) 0.013 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1550G(L517R) 0.005 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1551G(L517L) 0.005 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1621G(F541V) 0.003 A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.004 A1250C(K417T) A1331C(K444T) T1345C(Y449H) C1433A(T478K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.002 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1355G(L452R) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.001 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) 0.002 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1407T(S469S) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1605C(K535N) 0.0016 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) A1494C(Q498H) 0.003 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.435 0.029333333333333333 0.0852 0.102 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1518C(Q506H) 0.014 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) C1519A(P507T) 0.005 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) G1587T(K529N) 0.0026666666666666666 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) GT1505-1506del(502fs) 0.002 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1522G(Y508D) 0.001 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1540G(S514A) 0.004 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1542G(S514S) 0.007 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1544G(F515C) 0.007 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) T1663C(S555P) 0.0018 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1501T(N501Y) 0.092 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494CCC(Q498P) 0.005 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) 0.001 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.209 0.005333333333333333 0.0368 0.091 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) A1517C(Q506P) 0.002 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) AG1533-1534del(511fs) C1629T(F543F) 0.001 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) C1520A(P507Q) 0.004 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) C1524A(Y508*) 0.006 0.012 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) C1629T(F543F) 0.0026666666666666666 0.008799999999999999 0.075 A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.0014 A1250C(K417T) A1331C(K444T) T1355G(L452R) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.001 A1250C(K417T) A1331C(K444T) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1501T(N501Y) 0.0032 A1250C(K417T) A1331C(K444T) T1389C(P463P) A1432T(T478S) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0085 A1250C(K417T) A1331C(K444T) T1389C(P463P) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.032 A1250C(K417T) A1331C(K444T) T1389C(P463P) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) G1587A(K529K) 0.0075 A1250C(K417T) A1331C(K444T) T1469A(F490Y) A1494C(Q498H) 0.003 A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.006 A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.116 A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.466 A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502T(N501I) 0.002 A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) 0.002 0.0025 A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) 0.08 0.2515 A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) C1559A(A520E) 0.0005 A1250C(K417T) A1494C(Q498H) 0.0035 A1250C(K417T) AAT1318-1320GAG(N440E) 0.0015 A1250C(K417T) AAT1318-1320GAG(N440E) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0515 0.002 A1250C(K417T) AAT1318-1320GAG(N440E) A1451C(E484A) T1469A(F490Y) TT1488-1489del(496fs) A1494C(Q498H) 0.051 A1250C(K417T) AAT1318-1320GAG(N440E) G1365T(L455F) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.048 A1250C(K417T) AAT1318-1320GAG(N440E) G1365T(L455F) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) G1587A(K529K) 0.0065 A1250C(K417T) AAT1318-1320GAG(N440E) T1345C(Y449H) A1348T(N450Y) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.0016 A1250C(K417T) AAT1318-1320GAG(N440E) T1345C(Y449H) A1348T(N450Y) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) G1732T(D578Y) 0.009600000000000001 A1250C(K417T) AAT1318-1320GAG(N440E) T1345C(Y449H) T1380G(N460K) A1451C(E484A) A1494C(Q498H) 0.137 A1250C(K417T) AAT1318-1320GAG(N440E) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.166 A1250C(K417T) AAT1318-1320GAG(N440E) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1516A(Q506K) 0.003 A1250C(K417T) AAT1318-1320GAG(N440E) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1480C(S494P) CAA1492-1494TAC(Q498Y) 0.136 A1250C(K417T) AAT1318-1320GAG(N440E) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.002 A1250C(K417T) AAT1318-1320GAG(N440E) T1380G(N460K) C1425T(A475A) A1451C(E484A) CAA1492-1494TAC(Q498Y) 0.1365 A1250C(K417T) AAT1318-1320GAG(N440E) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) 0.286 A1250C(K417T) AAT1318-1320GAG(N440E) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.0018 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) A1451C(E484A) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.003 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) G1463T(C488F) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.003 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) 0.002 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) C1492T(Q498*) A1502C(N501T) 0.003 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) 0.001 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.0028 0.403 0.205 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1527G(R509R) 0.004 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) A1548C(E516D) 0.002 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1516A(Q506K) 0.006 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1519A(P507T) 0.003 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1520A(P507Q) 0.014 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1524A(Y508*) 0.019 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1537A(L513I) 0.001 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1559A(A520E) 0.006 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) G1507T(V503F) 0.004 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) G1511T(G504V) 0.001 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) G1546T(E516*) 0.001 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) G1574T(C525F) 0.0029999999999999996 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1512G(G504G) 0.003 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1513G(Y505D) 0.005 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1522G(Y508D) 0.001 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1540G(S514A) 0.005 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1543G(F515V) 0.002 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1545G(F515L) 0.005 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1557G(H519Q) 0.005 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1569C(T523T) 0.001 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) T1569C(T523T) T1693C(F565L) 0.0029999999999999996 A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) C1497A(P499P) A1502C(N501T) 0.001 A1250C(K417T) AAT1318-1320GCT(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.002 A1250C(K417T) C1383T(L461L) G1450A(E484K) A1501T(N501Y) 0.0375 A1250C(K417T) G1282T(D428Y) A1331C(K444T) T1345C(Y449H) A1451C(E484A) C1467T(Y489Y) T1469A(F490Y) A1494C(Q498H) 0.0023333333333333335 A1250C(K417T) G1291A(G431S) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.0125 A1250C(K417T) G1291A(G431S) A1331C(K444T) T1345C(Y449H) A1451C(E484A) C1467T(Y489Y) T1469A(F490Y) A1494C(Q498H) 0.011 A1250C(K417T) G1365T(L455F) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.001 A1250C(K417T) G1450A(E484K) A1501T(N501Y) 0.0015 A1250C(K417T) T1284C(D428D) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0036666666666666666 A1250C(K417T) T1469A(F490Y) A1494C(Q498H) C1709A(A570D) 0.0005 A1283C(D428A) T1355G(L452R) C1433A(T478K) 0.0033333333333333335 A1283C(D428A) T1355G(L452R) C1433A(T478K) T1455A(G485G) 0.0029999999999999996 A1283G(D428G) T1355G(L452R) C1433A(T478K) 0.004666666666666667 A1283G(D428G) T1355G(L452R) C1433A(T478K) T1455C(G485G) 0.0033333333333333335 A1288C(T430P) T1355G(L452R) C1433A(T478K) 0.005 A1288G(T430A) T1355G(L452R) C1433A(T478K) 0.012000000000000002 A1310C(N437T) T1355G(L452R) C1433A(T478K) 0.003 A1310G(N437S) T1355G(L452R) C1433A(T478K) AG1525-1526del(509fs) 0.02 A1316G(N439S) T1355G(L452R) C1433A(T478K) 0.0026666666666666666 A1319T(N440I) T1355G(L452R) C1433A(T478K) 0.482 A1319T(N440I) T1355G(L452R) C1433A(T478K) C1524A(Y508*) 0.007 A1331C(K444T) A1346C(Y449S) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0029999999999999996 A1331C(K444T) T1345C(Y449H) A1451C(E484A) C1467T(Y489Y) T1469A(F490Y) A1494C(Q498H) 0.008 A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0023333333333333335 0.001 A1331C(K444T) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1501T(N501Y) 0.0038 A1331G(K444R) T1355G(L452R) C1433A(T478K) 0.0006666666666666666 0.0008 A1352G(Y451C) T1355G(L452R) C1433A(T478K) 0.0016 A1501T(N501Y) 0.012 A1501T(N501Y) A1585T(K529*) C1709A(A570D) 0.002 A1501T(N501Y) A1605G(K535K) C1709A(A570D) 0.068 A1501T(N501Y) C1519A(P507T) C1709A(A570D) 0.001 A1501T(N501Y) C1709A(A570D) 0.217 0.1905 0.943 A1501T(N501Y) C1709A(A570D) C1753-1753del(585fs) 0.001 A1501T(N501Y) C1709A(A570D) T1745-1745del(582fs) 0.001 A1501T(N501Y) C1709A(A570D) T1751-1751del(584fs) 0.002 A1501T(N501Y) C1709A(A570D) T1754-1754del(585fs) 0.002 A1501T(N501Y) G1576A(G526R) C1709A(A570D) 0.002 A1641C(T547T) 0.002 A1641G(T547T) 0.507 A1641T(T547T) 0.002 AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.0013333333333333333 C1221-1221del(407fs) A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.0005 C1221-1221del(407fs) A1501T(N501Y) C1709A(A570D) 0.001 C1221-1221del(407fs) T1355G(L452R) C1433A(T478K) 0.0002 0.001 0.0003333333333333333 C1221T(V407V) A1224C(R408S) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1670G(K557R) 0.021 C1221T(V407V) T1355G(L452R) C1433A(T478K) 0.021 C1225T(Q409*) A1250C(K417T) A1331C(K444T) T1345C(Y449H) A1451C(E484A) C1467T(Y489Y) T1469A(F490Y) A1494C(Q498H) 0.018 C1225T(Q409*) A1250C(K417T) AAT1318-1320GCG(N440A) T1345C(Y449H) T1380G(N460K) C1425T(A475A) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502C(N501T) 0.02 C1225T(Q409*) T1355G(L452R) C1433A(T478K) 0.004399999999999999 C1244T(T415I) T1355G(L452R) C1433A(T478K) 0.018 C1296T(C432C) T1355G(L452R) C1433A(T478K) 0.0026666666666666666 C1433A(T478K) 0.105 0.003 0.004 C1559A(A520E) 0.002 C1709A(A570D) 0.004 G1216-1216del(406fs) A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.001 G1216-1216del(406fs) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.001 G1216-1216del(406fs) A1501T(N501Y) C1709A(A570D) 0.003 G1216-1216del(406fs) G1239T(G413G) T1355G(L452R) C1433A(T478K) 0.002 G1216-1216del(406fs) T1355G(L452R) C1433A(T478K) 0.001 0.002 0.0004 0.003 0.0016666666666666668 G1216-1216del(406fs) T1355G(L452R) C1433A(T478K) T1542C(S514S) 0.002 G1219-1219del(407fs) A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.0005 G1219-1219del(407fs) A1501T(N501Y) C1709A(A570D) 0.001 G1219-1219del(407fs) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.002 0.002 G1219-1219del(407fs) T1355G(L452R) C1433A(T478K) 0.0002 0.001 0.0003333333333333333 G1237A(G413R) T1355G(L452R) C1433A(T478K) 0.016666666666666666 G1237T(G413W) A1250C(K417T) A1331C(K444T) A1346G(Y449C) T1380G(N460K) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) 0.0005 G1237T(G413W) A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.06533333333333334 G1237T(G413W) A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) T1543G(F515V) 0.017333333333333333 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) T1456C(F486L) T1469A(F490Y) A1501T(N501Y) 0.0085 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) T1457C(F486S) T1469A(F490Y) A1501T(N501Y) 0.003 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) 0.2195 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) A1548C(E516D) 0.0005 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) C1524A(Y508*) 0.0025 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) T1512G(G504G) 0.001 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) T1513G(Y505D) 0.0015 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) G1423T(A475S) G1444T(G482C) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) 0.003 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) T1410A(T470T) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) 0.002 G1237T(G413W) A1250C(K417T) A1331C(K444T) TAT1345-1347CGT(Y449R) T1380G(N460K) T1410G(T470T) G1423T(A475S) A1451C(E484A) TTT1456-1458CCT(F486P) T1469A(F490Y) A1501T(N501Y) 0.0015 G1237T(G413W) A1250C(K417T) G1292N(G431?) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.018 G1238A(G413E) A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0018 G1238T(G413V) A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0016 G1239T(G413G) C1244A(T415N) T1355G(L452R) C1433A(T478K) 0.001 G1239T(G413G) T1355G(L452R) C1433A(T478K) 0.641 0.0016 0.01 G1239T(G413G) T1355G(L452R) C1433A(T478K) C1519A(P507T) 0.002 G1239T(G413G) T1355G(L452R) C1433A(T478K) C1520A(P507Q) 0.001 G1239T(G413G) T1355G(L452R) C1433A(T478K) C1524A(Y508*) 0.002 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1512G(G504G) 0.002 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1522G(Y508D) 0.001 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1538G(L513R) 0.002 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1539G(L513L) 0.001 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1540G(S514A) 0.001 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1542C(S514S) 0.084 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1542G(S514S) 0.002 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1551G(L517L) 0.002 G1239T(G413G) T1355G(L452R) C1433A(T478K) T1652A(V551D) 0.023 G1246-1246del(416fs) A1250C(K417T) A1331C(K444T) T1345C(Y449H) T1380G(N460K) G1411A(E471K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0012000000000000001 G1247A(G416E) T1355G(L452R) 0.033 G1251T(K417N) A1275T(L425F) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.022 G1251T(K417N) A1290G(T430T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1552T(L518L) C1640A(T547K) 0.022 G1251T(K417N) A1316C(N439T) T1320G(N440K) G1336A(G446S) A1402T(I468F) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.007 G1251T(K417N) A1316C(N439T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.005 G1251T(K417N) A1316G(N439S) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.015 G1251T(K417N) A1316G(N439S) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.019 G1251T(K417N) AG1278-1279del(426fs) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.007 G1251T(K417N) C1256T(A419V) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1552T(L518L) C1640A(T547K) A1705G(I569V) 0.023 G1251T(K417N) C1296T(C432C) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.024 G1251T(K417N) C1296T(C432C) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.026 G1251T(K417N) C1317T(N439N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.009 G1251T(K417N) G1258A(D420N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.021 G1251T(K417N) T1253C(I418T) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.023 G1251T(K417N) T1257C(A419A) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1582G(K528E) C1640A(T547K) 0.003 G1251T(K417N) T1257C(A419A) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1668T(N556N) 0.025 G1251T(K417N) T1257C(A419A) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1735T(P579S) 0.026 G1251T(K417N) T1257C(A419A) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1652A(V551D) 0.025 G1251T(K417N) T1257C(A419A) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1665C(S555S) 0.018 G1251T(K417N) T1257C(A419A) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1665G(S555S) 0.008 G1251T(K417N) T1266C(N422N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) T1274C(L425S) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) T1298G(V433G) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.005 G1251T(K417N) T1299C(V433V) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.015 G1251T(K417N) T1299C(V433V) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) GGT1486-1488ACT(G496T) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.009 G1251T(K417N) T1320G(N440K) A1325T(D442V) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.018 G1251T(K417N) T1320G(N440K) A1325T(D442V) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) GGT1486-1488ACT(G496T) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.016 G1251T(K417N) T1320G(N440K) A1330C(K444Q) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1722A(D574E) 0.009 G1251T(K417N) T1320G(N440K) A1330G(K444E) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1722A(D574E) 0.014 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1343T(N448I) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1552T(L518L) C1640A(T547K) 0.019 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1414C(I472L) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1414G(I472V) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.015 G1251T(K417N) T1320G(N440K) G1336A(G446S) A1421G(Q474R) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1552T(L518L) C1640A(T547K) 0.026 G1251T(K417N) T1320G(N440K) G1336A(G446S) C1433A(T478K) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1459T(N487Y) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) G1510T(G504C) T1513C(Y505H) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1512G(G504G) T1513C(Y505H) C1640A(T547K) 0.001 0.002 0.002 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513A(Y505N) C1552T(L518L) C1640A(T547K) 0.009 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513A(Y505N) C1640A(T547K) 0.002 0.004 0.003 0.007 0.013 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1518C(Q506H) C1640A(T547K) 0.003 0.015 0.007 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1582-1582del(528fs) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1585G(K529E) C1640A(T547K) 0.022 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) A1582G(K528E) C1640A(T547K) 0.023 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1520A(P507Q) C1640A(T547K) 1669-insertA(557fs) 0.007 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1640A(T547K) 0.003 0.006 0.122 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1640A(T547K) 1669-insertA(557fs) 0.027 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1519A(P507T) C1640A(T547K) 0.002 0.002 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1520A(P507Q) C1640A(T547K) 0.002 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1524A(Y508*) C1640A(T547K) 0.003 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1552T(L518L) C1640A(T547K) T1676C(F559S) 0.012 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1552T(L518L) C1640A(T547K) T1676G(F559C) 0.01 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1559A(A520E) C1640A(T547K) 0.002 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1580T(P527L) C1640A(T547K) 0.027 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.345 0.789 0.614 0.777 0.839 0.739 0.569 0.854 0.876 0.746 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1669-1669del(557fs) 0.007 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1672T(K558*) 0.024 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1737G(P579P) 0.021 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1678T(L560L) 0.023 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) C1715T(T572I) 0.022 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1651T(V551F) 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1702A(D568N) C1753T(L585F) 0.022 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1650A(G550G) 0.022 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1656A(L552L) A1721G(D574G) 0.019 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1659C(T553T) 0.017 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1659G(T553T) 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1675C(F559L) 0.009 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1675G(F559V) 0.01 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1677C(F559F) 0.007 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1677G(F559L) 0.01 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1710C(A570A) 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1710G(A570A) 0.018 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1734C(D578D) 0.01 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) CAA1516-1518AAC(Q506N) C1640A(T547K) 0.001 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1528T(V510L) C1640A(T547K) 0.001 0.002 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1534T(V512L) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1599A(L533L) C1640A(T547K) 0.025 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) G1634A(G545D) C1640A(T547K) 0.019 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1522G(Y508D) C1640A(T547K) 0.003 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1529G(V510G) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1532G(V511G) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1538G(L513R) C1640A(T547K) 0.003 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1539G(L513L) C1640A(T547K) 0.004 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1540G(S514A) C1640A(T547K) 0.002 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1542G(S514S) C1640A(T547K) 0.005 0.001 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1543G(F515V) C1640A(T547K) 0.005 0.003 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1544G(F515C) C1640A(T547K) 0.003 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1551G(L517L) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1622G(F541C) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) TAC1513-1515CAA(Y505Q) C1640A(T547K) 0.003 0.002 0.003 0.003 0.009 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) GGT1486-1488AGTTinsert(G496Sfsinsert) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) C1640A(T547K) 0.003 0.005 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) CAA1477-1479CGG(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.003 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) GGT1486-1488ACT(G496T) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1518C(Q506H) C1640A(T547K) 0.02 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) GGT1486-1488ACT(G496T) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.464 G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451T(E484V) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1518C(Q506H) C1640A(T547K) 0.032 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1359A(Y453*) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.013 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1359A(Y453*) G1430A(S477N) C1433A(T478K) A1451C(E484A) GGT1486-1488ACT(G496T) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.008 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1359C(Y453Y) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513A(Y505N) C1640A(T547K) 0.005 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) C1640A(T547K) 0.004 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.211 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) A1672T(K558*) 0.023 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) G1702A(D568N) C1753T(L585F) 0.023 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1650A(G550G) 0.023 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1710C(A570A) 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1375C(S459P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) T1485C(Y495Y) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) T1710G(A570A) 0.019 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1389C(P463P) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.006 G1251T(K417N) T1320G(N440K) G1336A(G446S) T1392C(F464F) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.01 G1251T(K417N) T1320G(N440K) G1336C(G446R) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.001 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) T1513A(Y505N) A1645T(T549S) A1669-1669del(557fs) 0.013 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) A1645T(T549S) A1669-1669del(557fs) 0.298 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1516A(Q506K) A1645T(T549S) A1669-1669del(557fs) 0.155 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1519A(P507T) A1645T(T549S) A1669-1669del(557fs) 0.006 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1559A(A520E) A1645T(T549S) A1669-1669del(557fs) 0.004 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) T1543G(F515V) A1645T(T549S) A1669-1669del(557fs) 0.002 G1251T(K417N) T1320G(N440K) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) A1493G(Q498R) A1501T(N501Y) TAC1513-1515CAA(Y505Q) A1645T(T549S) A1669-1669del(557fs) 0.004 G1251T(K417N) T1320G(N440K) T1323C(L441L) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.024 G1291T(G431C) T1355G(L452R) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.0026666666666666666 G1291T(G431C) T1355G(L452R) C1433A(T478K) 0.09733333333333333 G1291T(G431C) T1355G(L452R) C1433A(T478K) A1459C(N487H) 0.0026666666666666666 G1292N(G431?) T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.008 G1297T(V433F) T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) G1430A(S477N) GAA1450-1452del(E484del) TTT1456-1458CCT(F486P) T1469A(F490Y) C1492A(Q498K) C1496A(P499H) A1501T(N501Y) T1513C(Y505H) C1555A(H519N) C1681T(P561S) 0.0012000000000000001 G1303T(A435S) T1355G(L452R) C1433A(T478K) 0.002 G1307-1307del(436fs) T1355G(L452R) C1433A(T478K) 0.006 G1324T(D442Y) T1355G(L452R) C1433A(T478K) C1565T(A522V) 0.0032 G1332T(K444N) T1355G(L452R) C1433A(T478K) 0.004 G1339A(G447S) T1355G(L452R) C1433A(T478K) 0.018 G1339T(G447C) T1355G(L452R) C1433A(T478K) 0.0004 G1430A(S477N) 0.114 G1445T(G482V) G1447T(V483F) G1450A(E484K) 0.1 G1450A(E484K) 0.098 0.209 GGC1291-1293TNC(G431?) T1355G(L452R) C1433A(T478K) 0.0033333333333333335 T1212G(G404G) A1501T(N501Y) C1709A(A570D) 0.001 T1212G(G404G) G1213T(D405Y) A1501T(N501Y) C1709A(A570D) 0.003 T1212G(G404G) GAT1213-1215TGT(D405C) A1501T(N501Y) C1709A(A570D) 0.002 T1215-1215del(405fs) A1250C(K417T) A1331C(K444T) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) A1712G(D571G) 0.001 T1215-1215del(405fs) G1239T(G413G) T1355G(L452R) C1433A(T478K) 0.001 T1215-1215del(405fs) T1355G(L452R) C1433A(T478K) 0.001 0.0004 0.002 0.0006666666666666666 T1215G(D405E) G1216-1216del(406fs) A1501T(N501Y) C1709A(A570D) 0.002 T1220-1220del(407fs) A1501T(N501Y) C1709A(A570D) 0.001 T1220-1220del(407fs) T1355G(L452R) C1433A(T478K) 0.0002 T1233C(A411A) G1251T(K417N) T1320G(N440K) G1336A(G446S) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.009 T1281C(D427D) G1450A(E484K) 0.098 T1284-1284del(428fs) T1355G(L452R) C1433A(T478K) 0.098 T1284-1284del(428fs) T1355G(L452R) C1433A(T478K) A1459T(N487Y) 0.002 T1284C(D428D) T1355G(L452R) C1433A(T478K) 0.0018 T1305C(A435A) C1433A(T478K) 0.058 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) C1433A(T478K) 0.0008 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0013333333333333333 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) C1433A(T478K) 0.0012000000000000001 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) G1430A(S477N) GAA1450-1452del(E484del) TTT1456-1458CCT(F486P) C1492A(Q498K) C1496A(P499H) A1501T(N501Y) T1513C(Y505H) 0.0004 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) G1430A(S477N) GAA1450-1452del(E484del) TTT1456-1458CCT(F486P) C1492A(Q498K) C1496A(P499H) A1501T(N501Y) T1513C(Y505H) C1555A(H519N) 0.004 0.0026000000000000003 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) G1430A(S477N) GAA1450-1452del(E484del) TTT1456-1458CCT(F486P) C1492A(Q498K) C1496A(P499H) A1501T(N501Y) T1513C(Y505H) C1555A(H519N) C1681T(P561S) 0.010333333333333333 0.009 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) G1430A(S477N) GAA1450-1452del(E484del) TTT1456-1458CCT(F486P) T1469A(F490Y) C1492A(Q498K) C1496A(P499H) A1501T(N501Y) T1506C(G502G) T1513C(Y505H) C1555A(H519N) C1681T(P561S) 0.012 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) G1430A(S477N) GAA1450-1452del(E484del) TTT1456-1458GCT(F486A) C1492A(Q498K) C1496A(P499H) A1501T(N501Y) T1513C(Y505H) C1555A(H519N) C1629T(F543F) 0.0013333333333333333 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355A(L452Q) A1358T(Y453F) T1380G(N460K) G1430A(S477N) GAA1450-1452del(E484del) TTT1456-1458GCT(F486A) C1492A(Q498K) C1496A(P499H) A1501T(N501Y) T1513C(Y505H) C1555A(H519N) C1629T(F543F) C1681T(P561S) C1738A(Q580K) 0.0016666666666666668 T1320G(N440K) AAGGTTGGT1330-1338AGTdel(KVG444-446Sdel) T1355G(L452R) C1433A(T478K) 0.0008 T1334C(V445A) T1355G(L452R) C1433A(T478K) 0.0026666666666666666 T1345C(Y449H) T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.0006666666666666666 T1355G(L452R) 0.089 0.0005 0.005 0.005 T1355G(L452R) 1366-insertT(456fs) C1433A(T478K) 0.0014 T1355G(L452R) 1389-insertT(463fs) C1433A(T478K) 0.121 T1355G(L452R) 1389-insertT(463fs) T1405G(S469A) C1433A(T478K) 0.002 T1355G(L452R) A1378G(N460D) C1433A(T478K) 0.002 T1355G(L452R) A1408C(T470P) C1433A(T478K) 0.0002 T1355G(L452R) A1413C(E471D) C1433A(T478K) 0.007 T1355G(L452R) A1413G(E471E) C1433A(T478K) 0.012 T1355G(L452R) C1409A(T470N) C1433A(T478K) 0.157 T1355G(L452R) C1431T(S477S) C1433A(T478K) 0.002 T1355G(L452R) C1433A(T478K) 0.502 0.374 0.243 0.531 0.6 0.35966666666666663 0.609 0.322 0.929 0.38 0.014 0.465 0.419 0.63 0.414 0.5626666666666666 0.6875 0.494 0.035 0.056 0.141 T1355G(L452R) C1433A(T478K) 1693-insertT(565fs) 0.036 T1355G(L452R) C1433A(T478K) A1451C(E484A) 0.007 T1355G(L452R) C1433A(T478K) A1451T(E484V) 0.004 T1355G(L452R) C1433A(T478K) A1451T(E484V) T1722C(D574D) 0.0021999999999999997 T1355G(L452R) C1433A(T478K) A1452C(E484D) T1542C(S514S) 0.002 T1355G(L452R) C1433A(T478K) A1452G(E484E) 0.0033333333333333335 T1355G(L452R) C1433A(T478K) A1459C(N487H) 0.002 T1355G(L452R) C1433A(T478K) A1459G(N487D) 0.0013333333333333333 0.0012000000000000001 T1355G(L452R) C1433A(T478K) A1479G(Q493Q) 0.001 T1355G(L452R) C1433A(T478K) A1479G(Q493Q) T1722C(D574D) G1732-1732del(578fs) 0.002 T1355G(L452R) C1433A(T478K) A1514C(Y505S) 0.0002 T1355G(L452R) C1433A(T478K) A1518C(Q506H) 0.006 T1355G(L452R) C1433A(T478K) A1525C(R509R) 0.001 0.0008 0.001 T1355G(L452R) C1433A(T478K) A1527C(R509S) 0.0006000000000000001 T1355G(L452R) C1433A(T478K) A1527G(R509R) 0.0012000000000000001 T1355G(L452R) C1433A(T478K) A1527T(R509S) 0.0002 T1355G(L452R) C1433A(T478K) A1548C(E516D) 0.0004 0.004 T1355G(L452R) C1433A(T478K) A1560C(A520A) 0.001 T1355G(L452R) C1433A(T478K) A1582G(K528E) 0.002 T1355G(L452R) C1433A(T478K) A1603-1603del(535fs) 0.002 T1355G(L452R) C1433A(T478K) A1607T(N536I) 0.008799999999999999 T1355G(L452R) C1433A(T478K) A1609T(K537*) 0.0006666666666666666 0.0004 T1355G(L452R) C1433A(T478K) A1609T(K537*) T1653A(V551V) 0.0006666666666666666 T1355G(L452R) C1433A(T478K) A1611G(K537K) 0.04 T1355G(L452R) C1433A(T478K) A1611G(K537K) G1720A(D574N) 0.027 T1355G(L452R) C1433A(T478K) A1619C(N540T) 0.003 T1355G(L452R) C1433A(T478K) A1619G(N540S) 0.018 T1355G(L452R) C1433A(T478K) A1689G(Q563Q) 0.009600000000000001 T1355G(L452R) C1433A(T478K) A1703G(D568G) T1722C(D574D) 0.16233333333333333 T1355G(L452R) C1433A(T478K) AG1525-1526del(509fs) 0.139 T1355G(L452R) C1433A(T478K) C1436A(P479H) 0.002 T1355G(L452R) C1433A(T478K) C1471-1471del(491fs) T1722C(D574D) 0.0018 T1355G(L452R) C1433A(T478K) C1495T(P499S) 0.002 T1355G(L452R) C1433A(T478K) C1497A(P499P) 0.0008 T1355G(L452R) C1433A(T478K) C1515A(Y505*) 0.0004 0.001 T1355G(L452R) C1433A(T478K) C1515A(Y505*) AG1525-1526del(509fs) 0.003 T1355G(L452R) C1433A(T478K) C1516A(Q506K) 0.016 0.004 0.0018 0.002 0.003 T1355G(L452R) C1433A(T478K) C1516A(Q506K) AG1525-1526del(509fs) 0.002 T1355G(L452R) C1433A(T478K) C1519A(P507T) 0.001 0.0006000000000000001 T1355G(L452R) C1433A(T478K) C1519A(P507T) AG1525-1526del(509fs) 0.002 T1355G(L452R) C1433A(T478K) C1520A(P507Q) 0.001 0.001 0.0018000000000000002 0.0005 T1355G(L452R) C1433A(T478K) C1520A(P507Q) 1693-insertT(565fs) 0.003 T1355G(L452R) C1433A(T478K) C1524A(Y508*) 0.003 0.0013333333333333333 0.0062 0.002 0.011 0.016 0.005 0.0030000000000000005 0.0025 T1355G(L452R) C1433A(T478K) C1524A(Y508*) T1542C(S514S) 0.002 T1355G(L452R) C1433A(T478K) C1537A(L513I) 0.001 0.0006000000000000001 T1355G(L452R) C1433A(T478K) C1549A(L517I) 0.0002 T1355G(L452R) C1433A(T478K) C1555T(H519Y) 0.005999999999999999 T1355G(L452R) C1433A(T478K) C1555T(H519Y) G1708T(A570S) 0.08133333333333333 T1355G(L452R) C1433A(T478K) C1559A(A520E) 0.003 0.001 0.002 0.002 0.003 T1355G(L452R) C1433A(T478K) C1565A(A522E) 0.0002 0.001 T1355G(L452R) C1433A(T478K) C1565T(A522V) 0.018 0.0021999999999999997 0.105 T1355G(L452R) C1433A(T478K) C1565T(A522V) G1708T(A570S) 0.0008 T1355G(L452R) C1433A(T478K) C1579A(P527T) 0.001 T1355G(L452R) C1433A(T478K) C1640A(T547K) 0.002 T1355G(L452R) C1433A(T478K) C1640T(T547I) 0.0014 T1355G(L452R) C1433A(T478K) C1687A(Q563K) 0.0006666666666666666 0.0004 T1355G(L452R) C1433A(T478K) C1742A(T581K) 0.0003333333333333333 T1355G(L452R) C1433A(T478K) C1753-1753del(585fs) 0.0002 0.001 T1355G(L452R) C1433A(T478K) CT1499-1500del(500fs) 0.0033333333333333335 T1355G(L452R) C1433A(T478K) G1439A(C480Y) A1451C(E484A) 0.004 T1355G(L452R) C1433A(T478K) G1439C(C480S) A1451C(E484A) 0.002 T1355G(L452R) C1433A(T478K) G1439T(C480F) A1451C(E484A) 0.003 T1355G(L452R) C1433A(T478K) G1444T(G482C) 0.006 T1355G(L452R) C1433A(T478K) G1445A(G482D) G1447T(V483F) 0.0016666666666666668 T1355G(L452R) C1433A(T478K) G1445T(G482V) 0.007 0.002 T1355G(L452R) C1433A(T478K) G1447T(V483F) 0.0004 T1355G(L452R) C1433A(T478K) G1450T(E484*) 0.002 T1355G(L452R) C1433A(T478K) G1463T(C488F) 0.001 0.001 T1355G(L452R) C1433A(T478K) G1486T(G496C) 0.07933333333333333 T1355G(L452R) C1433A(T478K) G1504T(G502C) 0.177 T1355G(L452R) C1433A(T478K) G1505T(G502V) 0.0002 T1355G(L452R) C1433A(T478K) G1507T(V503F) 0.0014 T1355G(L452R) C1433A(T478K) G1507T(V503F) T1542C(S514S) 0.004 T1355G(L452R) C1433A(T478K) G1511T(G504V) 0.0004 T1355G(L452R) C1433A(T478K) G1526T(R509I) T1542C(S514S) 0.002 T1355G(L452R) C1433A(T478K) G1528T(V510L) 0.0002 T1355G(L452R) C1433A(T478K) G1534T(V512L) 0.0004 T1355G(L452R) C1433A(T478K) G1534T(V512L) T1542C(S514S) 0.002 T1355G(L452R) C1433A(T478K) G1546T(E516*) 0.0004 0.001 T1355G(L452R) C1433A(T478K) G1564C(A522P) 0.0252 T1355G(L452R) C1433A(T478K) G1570T(V524F) 0.0033333333333333335 T1355G(L452R) C1433A(T478K) G1587T(K529N) 0.0008 T1355G(L452R) C1433A(T478K) G1599T(L533F) 0.059 0.1165 T1355G(L452R) C1433A(T478K) G1634A(G545D) 0.166 T1355G(L452R) C1433A(T478K) G1642A(G548S) 0.0004 T1355G(L452R) C1433A(T478K) G1651T(V551F) 0.0026666666666666666 T1355G(L452R) C1433A(T478K) T1448A(V483D) AG1525-1526del(509fs) 0.012 T1355G(L452R) C1433A(T478K) T1448C(V483A) 0.003 T1355G(L452R) C1433A(T478K) T1455A(G485G) 0.002 T1355G(L452R) C1433A(T478K) T1455C(G485G) 0.0023333333333333335 T1355G(L452R) C1433A(T478K) T1455G(G485G) 0.0033333333333333335 T1355G(L452R) C1433A(T478K) T1488G(G496G) 0.08800000000000001 T1355G(L452R) C1433A(T478K) T1506C(G502G) 0.0018 T1355G(L452R) C1433A(T478K) T1512A(G504G) 0.0002 T1355G(L452R) C1433A(T478K) T1512G(G504G) 0.001 0.002 0.0013333333333333333 0.004200000000000001 0.002 0.002 0.006 0.0005 T1355G(L452R) C1433A(T478K) T1512G(G504G) T1542C(S514S) 0.007 T1355G(L452R) C1433A(T478K) T1513A(Y505N) 0.0002 T1355G(L452R) C1433A(T478K) T1513G(Y505D) 0.0006666666666666666 0.0024000000000000002 0.002 0.004 0.0003333333333333333 0.0005 T1355G(L452R) C1433A(T478K) T1513G(Y505D) T1542C(S514S) 0.003 T1355G(L452R) C1433A(T478K) T1522G(Y508D) 0.001 0.0004 0.003 T1355G(L452R) C1433A(T478K) T1522G(Y508D) T1542C(S514S) 0.002 T1355G(L452R) C1433A(T478K) T1529G(V510G) 0.0008 T1355G(L452R) C1433A(T478K) T1529G(V510G) T1542C(S514S) 0.002 T1355G(L452R) C1433A(T478K) T1532G(V511G) 0.0002 T1355G(L452R) C1433A(T478K) T1532G(V511G) T1542C(S514S) 0.003 T1355G(L452R) C1433A(T478K) T1538G(L513R) 0.0002 T1355G(L452R) C1433A(T478K) T1539G(L513L) T1542C(S514S) 0.005 T1355G(L452R) C1433A(T478K) T1540G(S514A) 0.003 0.0013333333333333333 0.0018000000000000002 0.001 0.003 0.002 T1355G(L452R) C1433A(T478K) T1542C(S514S) 0.08 0.923 0.049 0.149 T1355G(L452R) C1433A(T478K) T1542C(S514S) A1548C(E516D) 0.002 T1355G(L452R) C1433A(T478K) T1542C(S514S) G1546T(E516*) 0.002 T1355G(L452R) C1433A(T478K) T1542C(S514S) G1558T(A520S) 0.003 T1355G(L452R) C1433A(T478K) T1542C(S514S) T1543G(F515V) 0.004 T1355G(L452R) C1433A(T478K) T1542C(S514S) T1545G(F515L) 0.003 T1355G(L452R) C1433A(T478K) T1542C(S514S) T1550G(L517R) 0.003 T1355G(L452R) C1433A(T478K) T1542C(S514S) T1722A(D574E) 0.025 T1355G(L452R) C1433A(T478K) T1542C(S514S) T1722C(D574D) 0.009600000000000001 T1355G(L452R) C1433A(T478K) T1542C(S514S) T1751-1751del(584fs) 0.002 T1355G(L452R) C1433A(T478K) T1542C(S514S) T1754-1754del(585fs) 0.002 T1355G(L452R) C1433A(T478K) T1543A(F515I) 0.0013333333333333333 0.0016 T1355G(L452R) C1433A(T478K) T1543G(F515V) 0.003 0.012 0.0008 0.003 0.0003333333333333333 0.001 T1355G(L452R) C1433A(T478K) T1543G(F515V) T1722C(D574D) 0.0068000000000000005 T1355G(L452R) C1433A(T478K) T1544G(F515C) 0.006 0.001 0.0005 T1355G(L452R) C1433A(T478K) T1545G(F515L) 0.0014 0.003 0.0005 T1355G(L452R) C1433A(T478K) T1550G(L517R) 0.0004 T1355G(L452R) C1433A(T478K) T1551G(L517L) 0.0002 T1355G(L452R) C1433A(T478K) T1557G(H519Q) 0.0014 0.0005 T1355G(L452R) C1433A(T478K) T1575-1575del(525fs) 0.0064 T1355G(L452R) C1433A(T478K) T1588A(S530T) 0.012 T1355G(L452R) C1433A(T478K) T1588G(S530A) 0.008 T1355G(L452R) C1433A(T478K) T1627C(F543L) 0.002 0.0012000000000000001 T1355G(L452R) C1433A(T478K) T1627G(F543V) 0.0016666666666666668 0.0012000000000000001 T1355G(L452R) C1433A(T478K) T1635-1635del(545fs) 0.002 T1355G(L452R) C1433A(T478K) T1693G(F565V) 0.0002 T1355G(L452R) C1433A(T478K) T1694G(F565C) 0.0002 T1355G(L452R) C1433A(T478K) T1722C(D574D) 0.006 0.005666666666666667 0.012399999999999998 T1355G(L452R) C1433A(T478K) T1731A(R577R) 0.025 T1355G(L452R) C1433A(T478K) T1751-1751del(584fs) 0.0002 0.001 T1355G(L452R) C1433A(T478K) T1754-1754del(585fs) 0.001 0.0004 0.002 T1355G(L452R) C1433A(T478K) TCT1540-1542GCC(S514A) 0.003 T1355G(L452R) C1433G(T478R) 0.003 T1355G(L452R) C1433T(T478I) 0.001 T1355G(L452R) C1580T(P527L) 0.117 T1355G(L452R) G1365T(L455F) C1433A(T478K) 0.0026666666666666666 T1355G(L452R) G1395T(E465D) C1433A(T478K) 0.0006000000000000001 T1355G(L452R) G1399T(D467Y) C1433A(T478K) 0.0029999999999999996 T1355G(L452R) G1411A(E471K) C1433A(T478K) 0.021 T1355G(L452R) G1422T(Q474H) C1433A(T478K) 0.0002 0.001 T1355G(L452R) G1422T(Q474H) C1433A(T478K) T1590C(S530S) 0.0021999999999999997 T1355G(L452R) G1423T(A475S) C1433A(T478K) 0.0013333333333333333 0.0008 T1355G(L452R) G1426-1426del(476fs) C1433A(T478K) 0.0048000000000000004 T1355G(L452R) G1426T(G476C) C1433A(T478K) 0.0012000000000000001 T1355G(L452R) G1427A(G476D) C1433A(T478K) 0.011600000000000001 T1355G(L452R) G1430A(S477N) C1433A(T478K) A1451C(E484A) A1478G(Q493R) G1486A(G496S) A1493G(Q498R) A1501T(N501Y) T1513C(Y505H) C1640A(T547K) 0.006 T1355G(L452R) T1357C(Y453H) C1433A(T478K) 0.0016666666666666668 T1355G(L452R) T1382C(L461P) C1433A(T478K) 0.026 T1355G(L452R) T1389C(P463P) C1433A(T478K) C1565T(A522V) 0.004 T1355G(L452R) T1404A(I468I) C1433A(T478K) 0.0004 T1355G(L452R) T1410A(T470T) C1433A(T478K) 0.0045 T1355G(L452R) T1419C(Y473Y) C1433A(T478K) 0.1825 T1355G(L452R) T1419C(Y473Y) C1433A(T478K) C1524A(Y508*) 0.0035 T1366C(F456L) A1451C(E484A) TTT1456-1458CCT(F486P) T1480C(S494P) CAA1492-1494TAC(Q498Y) C1555A(H519N) C1715A(T572N) 0.171 0.0025 T1380G(N460K) A1451C(E484A) T1469A(F490Y) A1494C(Q498H) 0.0003333333333333333 T1380G(N460K) A1451C(E484A) T1469A(F490Y) CAA1492-1494TAC(Q498Y) A1502G(N501S) 0.0033333333333333335 T1410G(T470T) 0.002 T1469A(F490Y) C1477A(Q493K) T1480C(S494P) CAA1492-1494TAC(Q498Y) A1502C(N501T) C1555A(H519N) A1583G(K528R) C1715A(T572N) T1719C(T573T) 0.0025 T1512A(G504G) A1641G(T547T) 0.001 T1512G(G504G) 0.0025 T1513G(Y505D) 0.002