KEGG_A_class	KEGG_B_class	Pathway	Cyc_20-vs-Cyc_0 (171)	All (6729)	Pvalue	Qvalue	Pathway ID	Genes	K_IDs
Metabolism	Lipid metabolism	Steroid biosynthesis	10	19	6.552355e-12	1.638089e-09	ko00100	ENSGALG00000006198(LSS);ENSGALG00000048205(-);ENSGALG00000004106(DHCR7);ENSGALG00000009560(MSMO1);ENSGALG00000036915(SQLE);ENSGALG00000010798(DHCR24);ENSGALG00000016665(FDFT1);ENSGALG00000007493(NSDHL);ENSGALG00000009365(CYP51A1);MSTRG.6502(CYP24A1)	K01852+K01824+K00213+K07750+K00511+K09828+K00801+K07748+K05917+K07436
Metabolism	Metabolism of terpenoids and polyketides	Terpenoid backbone biosynthesis	5	21	0.000146177	1.827213e-02	ko00900	ENSGALG00000014948(HMGCR);ENSGALG00000007267(MVD);ENSGALG00000028880(FDPS);ENSGALG00000006723(-);ENSGALG00000014862(HMGCS1)	K00021+K01597+K00787+K01823+K01641
Metabolism	Global and overview maps	Metabolic pathways	55	1406	0.0003219507	2.682923e-02	ko01100	ENSGALG00000006134(HOGA1);ENSGALG00000011805(-);ENSGALG00000000109(AFMID);ENSGALG00000030781(CA2);ENSGALG00000006482(FAH);ENSGALG00000054784(-);ENSGALG00000047947(-);ENSGALG00000016442(RRM2);ENSGALG00000033365(ALDH1A3);ENSGALG00000008930(B3GNT2);ENSGALG00000054319(ELOVL6);ENSGALG00000031652(AK5);ENSGALG00000002899(AACS);ENSGALG00000006198(LSS);ENSGALG00000027874(CHAC1);ENSGALG00000014948(HMGCR);ENSGALG00000048205(-);ENSGALG00000013094(DDC);ENSGALG00000030614(ADH1C);ENSGALG00000003475(ACLY);ENSGALG00000004106(DHCR7);ENSGALG00000007267(MVD);ENSGALG00000009560(MSMO1);ENSGALG00000000808(-);ENSGALG00000009538(-);ENSGALG00000052712(-);ENSGALG00000036915(SQLE);ENSGALG00000010798(DHCR24);ENSGALG00000034655(ALDH18A1);ENSGALG00000016665(FDFT1);ENSGALG00000028880(FDPS);ENSGALG00000006300(LDHA);ENSGALG00000039575(AMD1);ENSGALG00000010402(HPGDS);ENSGALG00000001130(GALNT17);ENSGALG00000015180(PSAT1);ENSGALG00000043734(LIPG);ENSGALG00000014897(TYMS);ENSGALG00000040504(GGT5);ENSGALG00000012612(FBP2);ENSGALG00000007178(FADS2);ENSGALG00000006723(-);ENSGALG00000033635(PTGS2);ENSGALG00000012312(GCAT);ENSGALG00000048035(GCNT2);ENSGALG00000007493(NSDHL);ENSGALG00000014862(HMGCS1);ENSGALG00000005857(ALOX5);ENSGALG00000009365(CYP51A1);ENSGALG00000004270(ALDH1A2);ENSGALG00000012377(HNMT);ENSGALG00000023435(GATM);MSTRG.1212(--);MSTRG.12900(PHGDH);MSTRG.6502(CYP24A1)	K18123+K00699+K01432+K18245+K01555+K00710+K00789+K10808+K00129+K00741+K10203+K00939+K01907+K01852+K07232+K00021+K01824+K01593+K13951+K01648+K00213+K01597+K07750+K12322+K11153+K00789+K00511+K09828+K12657+K00801+K00787+K00016+K01611+K04097+K00710+K00831+K22284+K00560+K18592+K03841+K10226+K01823+K11987+K00639+K00742+K07748+K01641+K00461+K05917+K07249+K00546+K00613+K16855+K00058+K07436
Metabolism	Amino acid metabolism	Cysteine and methionine metabolism	6	46	0.0009942466	6.214041e-02	ko00270	ENSGALG00000047947(-);ENSGALG00000052712(-);ENSGALG00000006300(LDHA);ENSGALG00000039575(AMD1);ENSGALG00000015180(PSAT1);MSTRG.12900(PHGDH)	K00789+K00789+K00016+K01611+K00831+K00058
Human Diseases	Infectious diseases	Malaria	6	55	0.002549135	1.274568e-01	ko05144	ENSGALG00000010915(IL6);ENSGALG00000014804(THBS4);ENSGALG00000009626(THBS1);ENSGALG00000031430(-);ENSGALG00000033974(HGF);ENSGALG00000005257(-)	K05405+K04659+K16857+K06494+K05460+K06527
Organismal Systems	Nervous system	Serotonergic synapse	8	101	0.004005851	1.669105e-01	ko04726	ENSGALG00000043775(RAPGEF3);ENSGALG00000013094(DDC);ENSGALG00000040360(DUSP1);ENSGALG00000033635(PTGS2);ENSGALG00000015895(HTR1B);ENSGALG00000004246(SLC6A4);ENSGALG00000005857(ALOX5);ENSGALG00000010986(GNG4)	K08014+K01593+K21278+K11987+K04153+K05037+K00461+K04541
Environmental Information Processing	Membrane transport	ABC transporters	5	47	0.006470144	2.211637e-01	ko02010	ENSGALG00000006795(ABCG4);ENSGALG00000021395(-);ENSGALG00000016164(ABCG1);ENSGALG00000015433(ABCA1);ENSGALG00000053916(ABCB1)	K05680+K05651+K05679+K05641+K05658
Human Diseases	Cancers	Chemical carcinogenesis	5	48	0.007077239	2.211637e-01	ko05204	ENSGALG00000011805(-);ENSGALG00000033365(ALDH1A3);ENSGALG00000030614(ADH1C);ENSGALG00000010402(HPGDS);ENSGALG00000033635(PTGS2)	K00699+K00129+K13951+K04097+K11987
Metabolism	Amino acid metabolism	Tyrosine metabolism	4	35	0.01140754	2.897594e-01	ko00350	ENSGALG00000006482(FAH);ENSGALG00000033365(ALDH1A3);ENSGALG00000013094(DDC);ENSGALG00000030614(ADH1C)	K01555+K00129+K01593+K13951
Metabolism	Xenobiotics biodegradation and metabolism	Drug metabolism - cytochrome P450	4	36	0.01258474	2.897594e-01	ko00982	ENSGALG00000011805(-);ENSGALG00000033365(ALDH1A3);ENSGALG00000030614(ADH1C);ENSGALG00000010402(HPGDS)	K00699+K00129+K13951+K04097
Metabolism	Xenobiotics biodegradation and metabolism	Metabolism of xenobiotics by cytochrome P450	4	37	0.01383692	2.897594e-01	ko00980	ENSGALG00000011805(-);ENSGALG00000033365(ALDH1A3);ENSGALG00000030614(ADH1C);ENSGALG00000010402(HPGDS)	K00699+K00129+K13951+K04097
Human Diseases	Cancers	MicroRNAs in cancer	9	150	0.01390845	2.897594e-01	ko05206	ENSGALG00000040794(CCNE2);ENSGALG00000040079(ZFPM2);ENSGALG00000009626(THBS1);ENSGALG00000013929(PDGFRA);ENSGALG00000041459(DDIT4);ENSGALG00000033635(PTGS2);ENSGALG00000000379(ITGB3);ENSGALG00000053916(ABCB1);MSTRG.6502(CYP24A1)	K06626+K17442+K16857+K04363+K08270+K11987+K06493+K05658+K07436
Human Diseases	Cancers	Bladder cancer	4	38	0.01516557	2.916456e-01	ko05219	ENSGALG00000019061(MMP1);ENSGALG00000026070(-);ENSGALG00000009626(THBS1);ENSGALG00000003580(MMP2)	K01388+K08803+K16857+K01398
Metabolism	Amino acid metabolism	Glycine, serine and threonine metabolism	4	41	0.01962388	3.270647e-01	ko00260	ENSGALG00000015180(PSAT1);ENSGALG00000012312(GCAT);ENSGALG00000023435(GATM);MSTRG.12900(PHGDH)	K00831+K00639+K00613+K00058
Metabolism	Metabolism of cofactors and vitamins	Retinol metabolism	4	41	0.01962388	3.270647e-01	ko00830	ENSGALG00000011805(-);ENSGALG00000030614(ADH1C);ENSGALG00000009538(-);ENSGALG00000004270(ALDH1A2)	K00699+K13951+K11153+K07249
Metabolism	Global and overview maps	Biosynthesis of amino acids	5	65	0.02421792	3.784050e-01	ko01230	ENSGALG00000047947(-);ENSGALG00000052712(-);ENSGALG00000034655(ALDH18A1);ENSGALG00000015180(PSAT1);MSTRG.12900(PHGDH)	K00789+K00789+K12657+K00831+K00058
Metabolism	Amino acid metabolism	Arginine and proline metabolism	4	46	0.0286939	3.985264e-01	ko00330	ENSGALG00000006134(HOGA1);ENSGALG00000034655(ALDH18A1);ENSGALG00000039575(AMD1);ENSGALG00000023435(GATM)	K18123+K12657+K01611+K00613
Metabolism	Metabolism of other amino acids	Glutathione metabolism	4	46	0.0286939	3.985264e-01	ko00480	ENSGALG00000016442(RRM2);ENSGALG00000027874(CHAC1);ENSGALG00000010402(HPGDS);ENSGALG00000040504(GGT5)	K10808+K07232+K04097+K18592
Environmental Information Processing	Signal transduction	TGF-beta signaling pathway	6	94	0.03195849	3.994811e-01	ko04350	ENSGALG00000026137(CDKN2B);ENSGALG00000052541(-);ENSGALG00000009626(THBS1);ENSGALG00000009724(GREM1);ENSGALG00000034616(INHBA);ENSGALG00000014908(FST)	K04685+K04672+K16857+K23318+K04667+K04661
Environmental Information Processing	Signal transduction	TNF signaling pathway	6	94	0.03195849	3.994811e-01	ko04668	ENSGALG00000010915(IL6);ENSGALG00000031430(-);ENSGALG00000004370(MAP2K6);ENSGALG00000033635(PTGS2);ENSGALG00000005257(-);MSTRG.3910(LIF)	K05405+K06494+K04433+K11987+K06527+K05419
Organismal Systems	Endocrine system	Insulin secretion	5	74	0.03944356	4.684978e-01	ko04911	ENSGALG00000040256(RIMS2);ENSGALG00000002118(KCNMB1);ENSGALG00000031929(-);ENSGALG00000011104(GCG);ENSGALG00000039659(PCLO)	K15297+K04937+K04938+K05259+K16882
Metabolism	Lipid metabolism	Arachidonic acid metabolism	4	52	0.04239025	4.684978e-01	ko00590	ENSGALG00000010402(HPGDS);ENSGALG00000040504(GGT5);ENSGALG00000033635(PTGS2);ENSGALG00000005857(ALOX5)	K04097+K18592+K11987+K00461
Human Diseases	Cardiovascular diseases	Fluid shear stress and atherosclerosis	7	128	0.04402251	4.684978e-01	ko05418	ENSGALG00000035804(SQSTM1);ENSGALG00000031430(-);ENSGALG00000040360(DUSP1);ENSGALG00000004370(MAP2K6);ENSGALG00000000379(ITGB3);ENSGALG00000005257(-);ENSGALG00000003580(MMP2)	K14381+K06494+K21278+K04433+K06493+K06527+K01398
Metabolism	Carbohydrate metabolism	Glycolysis / Gluconeogenesis	4	53	0.04497579	4.684978e-01	ko00010	ENSGALG00000033365(ALDH1A3);ENSGALG00000030614(ADH1C);ENSGALG00000006300(LDHA);ENSGALG00000012612(FBP2)	K00129+K13951+K00016+K03841
Environmental Information Processing	Signal transduction	PI3K-Akt signaling pathway	16	403	0.04970368	4.970368e-01	ko04151	ENSGALG00000010915(IL6);ENSGALG00000040794(CCNE2);ENSGALG00000014804(THBS4);ENSGALG00000005974(COL6A1);ENSGALG00000042351(PIK3R6);ENSGALG00000012163(BDNF);ENSGALG00000009626(THBS1);ENSGALG00000013929(PDGFRA);ENSGALG00000041459(DDIT4);ENSGALG00000053526(NTF3);ENSGALG00000028376(FGF19);ENSGALG00000000379(ITGB3);ENSGALG00000033974(HGF);ENSGALG00000014455(LPAR5);ENSGALG00000008193(RELN);ENSGALG00000010986(GNG4)	K05405+K06626+K04659+K06238+K21290+K04355+K16857+K04363+K08270+K04356+K22603+K06493+K05460+K08390+K06249+K04541
Metabolism	Amino acid metabolism	Phenylalanine metabolism	2	16	0.06102045	5.867351e-01	ko00360	ENSGALG00000033365(ALDH1A3);ENSGALG00000013094(DDC)	K00129+K01593
Cellular Processes	Cellular community - eukaryotes	Focal adhesion	9	203	0.07324394	6.781846e-01	ko04510	ENSGALG00000014804(THBS4);ENSGALG00000005974(COL6A1);ENSGALG00000009626(THBS1);ENSGALG00000013929(PDGFRA);ENSGALG00000001793(MYL10);ENSGALG00000000379(ITGB3);ENSGALG00000033974(HGF);ENSGALG00000008193(RELN);ENSGALG00000011708(MYLK)	K04659+K06238+K16857+K04363+K12756+K06493+K05460+K06249+K00907
Environmental Information Processing	Signaling molecules and interaction	ECM-receptor interaction	5	93	0.08733736	7.797979e-01	ko04512	ENSGALG00000014804(THBS4);ENSGALG00000005974(COL6A1);ENSGALG00000009626(THBS1);ENSGALG00000000379(ITGB3);ENSGALG00000008193(RELN)	K04659+K06238+K16857+K06493+K06249
Cellular Processes	Cell growth and death	p53 signaling pathway	4	68	0.09390855	7.956023e-01	ko04115	ENSGALG00000017204(SESN3);ENSGALG00000040794(CCNE2);ENSGALG00000016442(RRM2);ENSGALG00000009626(THBS1)	K10141+K06626+K10808+K16857
Environmental Information Processing	Signaling molecules and interaction	Cell adhesion molecules (CAMs)	7	156	0.1018371	7.956023e-01	ko04514	ENSGALG00000001621(CLDN5);ENSGALG00000001177(CD34);ENSGALG00000039196(NECTIN1);ENSGALG00000031430(-);ENSGALG00000000158(DMA);ENSGALG00000011350(NEGR1);ENSGALG00000005257(-)	K06087+K06474+K06081+K06494+K06752+K06775+K06527